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Sample records for kernkraftwerk isar

  1. Coherent Multistatic ISAR Imaging

    Dorp, Ph. van; Otten, M.P.G.; Verzeilberg, J.M.M.

    2012-01-01

    This paper presents methods for Coherent Multistatic Radar Imaging for Non Cooperative Target Recognition (NCTR) with a network of radar sensors. Coherent Multistatic Radar Imaging is based on an extension of existing monostatic ISAR algorithms to the multistatic environment. The paper describes the

  2. Sports fishers against Kernkraftwerk Grohnde: No success

    1980-09-01

    With its decision of 18 July 1980, the Lueneburg Higher Administrative Court has dismissed the action of ten sport fishers' clubs against the decision of the Hanover Administrative Court of 2 June 1977 which had refused their application to re-establish the suspensive power of their actions against the enforceable first part-construction permit for Kernkraftwerk Grohnde on the Weser River. The Lueneburg Higher Administrative Court confirms the legality of the decision for immediate enforcement of nuclear construction permits as far as there is no irreparable damage to the rights of those concerned. The binding force of the decision concerning the site in the first part-construction permit is mentioned.

  3. Kernkraftwerk Brunsbuettel (KKB). Annual report 2001

    2002-04-01

    In the business year from 1 January through to 31 December 2001, Kernkraftwerk Brunsbuettel GmbH achieved a gross electric output of 6,010 GWh. The total net output transmitted to the two partner utilities Hamburger Electricitaets-Werke AG (HEW) and E.ON Kernkraft GmbH (E.ON KK) amounted to 5,764 GWh. Although the availability time ratio was 94.1 % (94.4 % previous year), the capacity factor was only 85.3 % (85.6 % previous year). This was due to postponement of the refuelling operation, spent fuel transports away from the reactor being delayed as a consequence of the political situation. The resulting considerable period of stretch-out operation with declining power output reduced the net output to 498 GWh. Otherwise, the capacity factor could have been 92.7 %. The short shutdown period of 23 days for power plant inspection inclusive of refuelling operation (20 days previous year) has had a positive impact on the operating data of the year 2001. The aggregate total gross electric output generated by the power station since it is operated by Kernkraftwerk Brunsbuettel GmbH amounts to 98,032 GWh. (orig./CB) [de

  4. Ship dynamics for maritime ISAR imaging.

    Doerry, Armin Walter

    2008-02-01

    Demand is increasing for imaging ships at sea. Conventional SAR fails because the ships are usually in motion, both with a forward velocity, and other linear and angular motions that accompany sea travel. Because the target itself is moving, this becomes an Inverse- SAR, or ISAR problem. Developing useful ISAR techniques and algorithms is considerably aided by first understanding the nature and characteristics of ship motion. Consequently, a brief study of some principles of naval architecture sheds useful light on this problem. We attempt to do so here. Ship motions are analyzed for their impact on range-Doppler imaging using Inverse Synthetic Aperture Radar (ISAR). A framework for analysis is developed, and limitations of simple ISAR systems are discussed.

  5. Sports fishers against Kernkraftwerk Grohnde: No success

    Anon.

    1980-01-01

    With its decision of 18 July 1980, the Lueneburg Higher Administrative Court has dismissed the action of ten sport fishers' clubs against the decision of the Hanover Administrative Court of June 2 June 1977 which had refused their application to re-establish the suspensive power of their actions against the enforceable first part-construction permit for Kernkraftwerk Grohnde on the Weser River. The Lueneburg Higher Administrative Court confirms the legality of the decision for immediate enforcement of nuclear construction permits as far as there is no irreparable damage to the rights of those concerned. The binding force of the decision concerning the site in the first part-construction permit is mentioned. (HSCH) [de

  6. ISAR imaging using the instantaneous range instantaneous Doppler method

    Wazna, TM

    2015-10-01

    Full Text Available In Inverse Synthetic Aperture Radar (ISAR) imaging, the Range Instantaneous Doppler (RID) method is used to compensate for the nonuniform rotational motion of the target that degrades the Doppler resolution of the ISAR image. The Instantaneous Range...

  7. Distributed MIMO-ISAR Sub-image Fusion Method

    Gu Wenkun

    2017-02-01

    Full Text Available The fast fluctuation associated with maneuvering a target’s radar cross-section often affects the imaging performance stability of traditional monostatic Inverse Synthetic Aperture Radar (ISAR. To address this problem, in this study, we propose an imaging method based on the fusion of sub-images of frequencydiversity-distributed multiple Input-Multiple Output-Inverse Synthetic Aperture Radar (MIMO-ISAR. First, we establish the analytic expression of a two-dimensional ISAR sub-image acquired by different channels of distributed MIMO-ISAR. Then, we derive the distance and azimuth distortion factors of the image acquired by the different channels. By compensating for the distortion of the ISAR image, we ultimately realize distributed MIMO-ISAR fusion imaging. Simulations verify the validity of this imaging method using distributed MIMO-ISAR.

  8. The NPP Isar comprehensive Aging Management Program

    Zander, Andre; Ertl, Stefan

    2012-01-01

    The majority of System, Structure and Components (SSC) in a nuclear power plants are designed to experience a service life, which is far above the intended design life. In most cases, only a small percentage of SSCs are subject to significant aging effects, which may affect the integrity or the function of the component. The process of aging management (AM) has the objective to monitor and control degradation effects which may compromise safety functions of the plant. And furthermore, to ensure, that testing and maintenance programs sufficiently provide preventive measures to control degradation effects. Safety-related aspects and the targeted high availability of the power plant as well as the requirements stipulated by German regulatory authorities prompted the operator of NPP ISAR to introduce an aging surveillance program. The NPP Isar as well as the German NPPs has to be following in the scope of aging management the KTA 1403 guideline. The NPP Isar surveillance program based on the KTA 1403 guideline covers the following aspects: - Scoping and screening of safety relevant Systems, Structures and Components (SSC); - Identification of possible degradation mechanisms for safety relevant SSC; - Ensure, that testing and maintenance programs sufficiently provide preventive measures to control degradation effects; - Transferability check of industry experience (internal and external events); - Annual preparation of an AM status report. (author)

  9. Towards Inverse Synthetic Aperture Radar (ISAR) for small sea vessels

    Abdul Gaffar, MY

    2006-12-01

    Full Text Available Aperture Radar (ISAR) for Small Sea Vessels M.Y. Abdul Gaffar Council for Scientific and Industrial Research University of Cape Town Slide 2 © CSIR 2006 www.csir.co.za What is ISAR? • Technique that produces cross range...

  10. Eco-audit at the site of the nuclear power plants Isar 1 and Isar 2

    Brosche, D.

    2000-01-01

    The voluntary eco-audits for the nuclear power plants Isar 1 and 2 were the first ones for a nuclear power plant in Germany under the Council Eco Regulation of the European Commission and have shown that the environmental protection is actively practiced in accordance with the environmental policy of Bayernwerk AG. With the early integration of all partners and a careful planning, such audits can be performed efficiently and at a reasonable expenditure. (orig.) [de

  11. A time domain phase-gradient based ISAR autofocus algorithm

    Nel, W

    2011-10-01

    Full Text Available . Results on simulated and measured data show that the algorithm performs well. Unlike many other ISAR autofocus techniques, the algorithm does not make use of several computationally intensive iterations between the data and image domains as part...

  12. Action of the city of Schweinfurt against Kernkraftwerk Grafenrheinfeld recognized

    Anon.

    1979-01-01

    In the appeal proceedings, the Bavarian Administrative Court with its interim decision of April 9, 1979 - No. 167 VI 74 - has recognized the action of the city of Schweinfurt against the state of Bavaria to set aside the 1st part license for the construction of Kernkraftwerk Grafenrheinfeld, although the right for action was limited to the city's legal position concerning planning authority, drinking water supply, and a city-owned lake used for swimming. Appeal was allowed. The city has lodged an appeal. The decision of the Administrative Court of Wuerzburg of March 25, 1977, which was contested by the appeal, had also recognized the city's rights but dismissed the action as being unfounded. Guidelines and reasons for the decision of the Bavarian Administrative Court are given in full wording. (orig./HP) 891 HP/orig.- 892 HIS [de

  13. Target Identification Using Harmonic Wavelet Based ISAR Imaging

    Shreyamsha Kumar, B. K.; Prabhakar, B.; Suryanarayana, K.; Thilagavathi, V.; Rajagopal, R.

    2006-12-01

    A new approach has been proposed to reduce the computations involved in the ISAR imaging, which uses harmonic wavelet-(HW) based time-frequency representation (TFR). Since the HW-based TFR falls into a category of nonparametric time-frequency (T-F) analysis tool, it is computationally efficient compared to parametric T-F analysis tools such as adaptive joint time-frequency transform (AJTFT), adaptive wavelet transform (AWT), and evolutionary AWT (EAWT). Further, the performance of the proposed method of ISAR imaging is compared with the ISAR imaging by other nonparametric T-F analysis tools such as short-time Fourier transform (STFT) and Choi-Williams distribution (CWD). In the ISAR imaging, the use of HW-based TFR provides similar/better results with significant (92%) computational advantage compared to that obtained by CWD. The ISAR images thus obtained are identified using a neural network-based classification scheme with feature set invariant to translation, rotation, and scaling.

  14. Performance limits for maritime Inverse Synthetic Aperture Radar (ISAR)

    Doerry, Armin Walter [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2013-11-01

    The performance of an Inverse Synthetic Aperture Radar (ISAR) system depends on a variety of factors, many which are interdependent in some manner. In this report we specifically examine ISAR as applied to maritime targets (e.g. ships). It is often difficult to get your arms around the problem of ascertaining achievable performance limits, and yet those limits exist and are dictated by physics. This report identifies and explores those limits, and how they depend on hardware system parameters and environmental conditions. Ultimately, this leads to a characterization of parameters that offer optimum performance for the overall ISAR system. While the information herein is not new to the literature, its collection into a single report hopes to offer some value in reducing the seek time.

  15. Quality measures for HRR alignment based ISAR imaging algorithms

    Janse van Rensburg, V

    2013-05-01

    Full Text Available Some Inverse Synthetic Aperture Radar (ISAR) algorithms form the image in a two-step process of range alignment and phase conjugation. This paper discusses a comprehensive set of measures used to quantify the quality of range alignment, with the aim...

  16. Kernkraftwerke Lippe-Ems (KLE). 1997 annual report

    1998-01-01

    The Kernkraftwerke Lippe-Ems GmbH (KLE) is the operator of the Emsland reactor station at Lingen (Ems), equipped with a 1300 MW PWR. The partners of KLE are VEW ENERGIE, PreussenElektra, and RWE Energie. The nuclear power station was used over the reporting period as a base-load power plant operating under full-load conditions. The total gross electricity output was 11235 million kWh, which is the highest annual total output ever since start-up. The net electricity generation over the reporting amounted to 10650 million kWh. The personnel employed with KLE at the end of the reporting year amounts to 287. The reduction of the nominal capital of the GmbH to 900 000 TDM, decided by the partners in 1996, became legally effective in April 1997. The dominant features of the structure of expenses of KLE are expenses for the fuel inventory and spent fuel management, for the legally required reserves for decommissioning, and writeoffs. The contractual electric power rates negotiated with the partners cover all load and capacity-dependent expenses; in addition, the partners receive their contractual shares of the profit resulting from interests paid on the nominal capital. (orig./CB) [de

  17. `Mountain Hut` promotion programme of Isar Amperwerke - interim project report; Foerderprogramm Berghuetten der Isar-Amperwerke - Projektstatus

    Pfeiffer, G.; Reiner, H. [Isar-Amperwerke AG, Abt. ETK, Muenchen (Germany)

    1997-12-31

    The purpose of the ``Mountain Hut`` promotion programme is to accelerate the conversion of mountain hut power supply systems to renewables. Under this programme, which exclusively promotes the installation of renewable energy systems (hydropower, solar energy, wind power, biomass), Isar Amperwerke contributes up to a maximum of 50% of the investment costs. The present article briefly reports on four projects that have already been realised. (HW) [Deutsch] Mit dem Foerderprogramm `Berghuetten` soll die Stromversorgung von Berghuetten staerker auf erneuerbare Energietraeger umgestellt werden. Die Zuschussrate der Isar-Amper-Werke betraegt dabei maximal 50%, wobei nur regenerative Energien (Wasserkraft, Solarenergie, Windkraft und Biomasse) gefoerdert werden. Der vorliegende Beitrag gibt einen Ueberblick ueber vier schon realisierte Projekte. (HW)

  18. Using image quality measures and features to choose good images for classification of ISAR imagery

    Steyn, JM

    2014-10-01

    Full Text Available the quality measures and to determine the minimum dwell-time for ISAR image formation. Keywords—ISAR (inverse synthetic aperture radar), Dwell-time, Quality Measure, Image Contrast, Image Entropy, SNR (signal-to-noise ratio), Maritime Vessels ...

  19. Isar-2 nuclear power station twenty-five years

    Fischer, Erwin; Luginger, Markus

    2013-01-01

    The Isar-2 nuclear power station (KKI 2) began commercial power operation on April 9, 1988. In these past 25 years the plant generated a total of approx. 285 billion kWh of electricity. The annual electricity production of KKI 2 of approx. 12 billion kWh corresponds to a share of approx. 15 % in the cumulated Bavarian electricity production. This amount of electricity, theoretically, could supply some 3 million three person households, or meet two thirds of the electricity requirement of the Bavarian industry, for one year. In its 25 years of power operation the Isar-2 nuclear power plant has recorded the highest annual gross electricity production of all nuclear power plants in the world nine times so far. A plant performance as impressive as this necessitates a plant availability far above the average. This, in turn, is based on short revision times and faultfree plant operation. However, high plant safety and availability must not be taken for granted, but are the result of responsible, safety-minded plant operation combined with continuous plant optimization and permanent execution of comprehensive checks, inspections, and maintenance measures. Besides plant technology also organization and administration were permanently advanced and adapted to changing requirements so as to safeguard reliable, safe, and non-polluting plant operation.

  20. Kernkraftwerke Lippe-Ems (KLE). Report on the business year 1994

    1995-01-01

    In the business year under report, Kernkraftwerk Emsland generated base load power and ran to capacity. Gross power generation was again enhanced as compared to the year previously, attaining the so far highest annual value with 11106 million kWh. Net power generation stood at 10526 million kWh in 1994. The expense structure of KLE is essentially determined by expenditure for fuel and fuel disposal, power plant decommissioning, and capital service. There were 287 staff. The report contains financial data. (orig./HP) [de

  1. Geometric shapes inversion method of space targets by ISAR image segmentation

    Huo, Chao-ying; Xing, Xiao-yu; Yin, Hong-cheng; Li, Chen-guang; Zeng, Xiang-yun; Xu, Gao-gui

    2017-11-01

    The geometric shape of target is an effective characteristic in the process of space targets recognition. This paper proposed a method of shape inversion of space target based on components segmentation from ISAR image. The Radon transformation, Hough transformation, K-means clustering, triangulation will be introduced into ISAR image processing. Firstly, we use Radon transformation and edge detection to extract space target's main body spindle and solar panel spindle from ISAR image. Then the targets' main body, solar panel, rectangular and circular antenna are segmented from ISAR image based on image detection theory. Finally, the sizes of every structural component are computed. The effectiveness of this method is verified using typical targets' simulation data.

  2. Quaternion-based transformation for extraction of image-generating Doppler for ISAR

    Abdul Gaffar, MY

    2008-10-01

    Full Text Available contributing motion that is useful to the ISAR imaging process; the contributing motion consists of the Doppler generating axis and the effective angle of rotation. This letter presents a quaternion-based transformation that converts measured attitude...

  3. ISAR Imaging of Maneuvering Targets Based on the Modified Discrete Polynomial-Phase Transform

    Yong Wang

    2015-09-01

    Full Text Available Inverse synthetic aperture radar (ISAR imaging of a maneuvering target is a challenging task in the field of radar signal processing. The azimuth echo can be characterized as a multi-component polynomial phase signal (PPS after the translational compensation, and the high quality ISAR images can be obtained by the parameters estimation of it combined with the Range-Instantaneous-Doppler (RID technique. In this paper, a novel parameters estimation algorithm of the multi-component PPS with order three (cubic phase signal-CPS based on the modified discrete polynomial-phase transform (MDPT is proposed, and the corresponding new ISAR imaging algorithm is presented consequently. This algorithm is efficient and accurate to generate a focused ISAR image, and the results of real data demonstrate the effectiveness of it.

  4. Resolution and Micro-Doppler Effect in Bi-ISAR System (in English

    Deng Dong-hu

    2013-06-01

    Full Text Available Compared to the monostatic radar, bistatic radar has many special characteristics because of its spatial complexity. Bistatic Inverse Synthetic Aperture Radar (Bi-ISAR can be employed as a radar imaging tool for obtaining non-cooperative target images. In this study, we first analyze the range and azimuth resolution of a Bi-ISAR system. To analyze this azimuth resolution and its spatial-variety characteristic, a definition called con-Doppler bandwidth is introduced, which helps overcome the difficulty of the target’s viewing angle diversity calculation. Then, a detailed investigation is conducted to study the micro-Doppler effect caused by the vibration and the rotation of the target in the Bi-ISAR system. By comparing the difference in the micro-Doppler effect between the Bi-ISAR system and the Mono-ISAR system, we modify the extended Hough transform to extract the real micro-motion features of the targets. Finally, we provide some simulation results to validate the theoretical derivation and to illustrate the effectiveness of the proposed method.

  5. ISAR Imaging of Ship Targets Based on an Integrated Cubic Phase Bilinear Autocorrelation Function

    Jibin Zheng

    2017-03-01

    Full Text Available For inverse synthetic aperture radar (ISAR imaging of a ship target moving with ocean waves, the image constructed with the standard range-Doppler (RD technique is blurred and the range-instantaneous-Doppler (RID technique has to be used to improve the image quality. In this paper, azimuth echoes in a range cell of the ship target are modeled as noisy multicomponent cubic phase signals (CPSs after the motion compensation and a RID ISAR imaging algorithm is proposed based on the integrated cubic phase bilinear autocorrelation function (ICPBAF. The ICPBAF is bilinear and based on the two-dimensionally coherent energy accumulation. Compared to five other estimation algorithms, the ICPBAF can acquire higher cross term suppression and anti-noise performance with a reasonable computational cost. Through simulations and analyses with the synthetic model and real radar data, we verify the effectiveness of the ICPBAF and corresponding RID ISAR imaging algorithm.

  6. A Novel Adaptive Joint Time Frequency Algorithm by the Neural Network for the ISAR Rotational Compensation

    Zisheng Wang

    2018-02-01

    Full Text Available We propose a novel adaptive joint time frequency algorithm combined with the neural network (AJTF-NN to focus the distorted inverse synthetic aperture radar (ISAR image. In this paper, a coefficient estimator based on the artificial neural network (ANN is firstly developed to solve the time-consuming rotational motion compensation (RMC polynomial phase coefficient estimation problem. The training method, the cost function and the structure of ANN are comprehensively discussed. In addition, we originally propose a method to generate training dataset sourcing from the ISAR signal models with randomly chosen motion characteristics. Then, prediction results of the ANN estimator is used to directly compensate the ISAR image, or to provide a more accurate initial searching range to the AJTF for possible low-performance scenarios. Finally, some simulation models including the ideal point scatterers and a realistic Airbus A380 are employed to comprehensively investigate properties of the AJTF-NN, such as the stability and the efficiency under different signal-to-noise ratios (SNRs. Results show that the proposed method is much faster than other prevalent improved searching methods, the acceleration ratio are even up to 424 times without the deterioration of compensated image quality. Therefore, the proposed method is potential to the real-time application in the RMC problem of the ISAR imaging.

  7. Adaptive ISAR Imaging of Maneuvering Targets Based on a Modified Fourier Transform.

    Wang, Binbin; Xu, Shiyou; Wu, Wenzhen; Hu, Pengjiang; Chen, Zengping

    2018-04-27

    Focusing on the inverse synthetic aperture radar (ISAR) imaging of maneuvering targets, this paper presents a new imaging method which works well when the target's maneuvering is not too severe. After translational motion compensation, we describe the equivalent rotation of maneuvering targets by two variables-the relative chirp rate of the linear frequency modulated (LFM) signal and the Doppler focus shift. The first variable indicates the target's motion status, and the second one represents the possible residual error of the translational motion compensation. With them, a modified Fourier transform matrix is constructed and then used for cross-range compression. Consequently, the imaging of maneuvering is converted into a two-dimensional parameter optimization problem in which a stable and clear ISAR image is guaranteed. A gradient descent optimization scheme is employed to obtain the accurate relative chirp rate and Doppler focus shift. Moreover, we designed an efficient and robust initialization process for the gradient descent method, thus, the well-focused ISAR images of maneuvering targets can be achieved adaptively. Human intervention is not needed, and it is quite convenient for practical ISAR imaging systems. Compared to precedent imaging methods, the new method achieves better imaging quality under reasonable computational cost. Simulation results are provided to validate the effectiveness and advantages of the proposed method.

  8. Investigation of 3-D RCS Image formation of ships using ISAR

    Lord, RT

    2006-05-01

    Full Text Available Conventional Inverse Synthetic Aperture Radar (ISAR) utilises the rotational motion of a target such as a ship or an aircraft to obtain a 2-D image of the target’s radar cross section (RCS) profile from a coherent radar system. This concept can...

  9. Application of radon transforms and time-frequency representations to ISAR imagery

    Steeghs, T.P.H.; Gelsema, S.J.

    2003-01-01

    The use of ISAR imagery for Automatic Target Recognition is seriously hampered by the difficulty of target motion compensation. Phase perturbations that result from target maneuvers during the processing interval need to be corrected for. In a previous paper, we demonstrated the use of the local

  10. Distributed ISAR Subimage Fusion of Nonuniform Rotating Target Based on Matching Fourier Transform.

    Li, Yuanyuan; Fu, Yaowen; Zhang, Wenpeng

    2018-06-04

    In real applications, the image quality of the conventional monostatic Inverse Synthetic Aperture Radar (ISAR) for the maneuvering target is subject to the strong fluctuation of Radar Cross Section (RCS), as the target aspect varies enormously. Meanwhile, the maneuvering target introduces nonuniform rotation after translation motion compensation which degrades the imaging performance of the conventional Fourier Transform (FT)-based method in the cross-range dimension. In this paper, a method which combines the distributed ISAR technique and the Matching Fourier Transform (MFT) is proposed to overcome these problems. Firstly, according to the characteristics of the distributed ISAR, the multiple channel echoes of the nonuniform rotation target from different observation angles can be acquired. Then, by applying the MFT to the echo of each channel, the defocused problem of nonuniform rotation target which is inevitable by using the FT-based imaging method can be avoided. Finally, after preprocessing, scaling and rotation of all subimages, the noncoherent fusion image containing all the RCS information in all channels can be obtained. The accumulation coefficients of all subimages are calculated adaptively according to the their image qualities. Simulation and experimental data are used to validate the effectiveness of the proposed approach, and fusion image with improved recognizability can be obtained. Therefore, by using the distributed ISAR technique and MFT, subimages of high-maneuvering target from different observation angles can be obtained. Meanwhile, by employing the adaptive subimage fusion method, the RCS fluctuation can be alleviated and more recognizable final image can be obtained.

  11. Focusing ISAR Images using Fast Adaptive Time-Frequency and 3D Motion Detection on Simulated and Experimental Radar Data

    Brinkman, Wade

    2005-01-01

    ...) and the Particle Swarm Optimization (PSO) algorithm were designed to rapidly traverse the solution space in order to find the parameters that would bring the ISAR image into focus in the cross-range...

  12. Sensitivity of Attitude Determination on the Model Assumed for ISAR Radar Mappings

    Lemmens, S.; Krag, H.

    2013-09-01

    Inverse synthetic aperture radars (ISAR) are valuable instrumentations for assessing the state of a large object in low Earth orbit. The images generated by these radars can reach a sufficient quality to be used during launch support or contingency operations, e.g. for confirming the deployment of structures, determining the structural integrity, or analysing the dynamic behaviour of an object. However, the direct interpretation of ISAR images can be a demanding task due to the nature of the range-Doppler space in which these images are produced. Recently, a tool has been developed by the European Space Agency's Space Debris Office to generate radar mappings of a target in orbit. Such mappings are a 3D-model based simulation of how an ideal ISAR image would be generated by a ground based radar under given processing conditions. These radar mappings can be used to support a data interpretation process. E.g. by processing predefined attitude scenarios during an observation sequence and comparing them with actual observations, one can detect non-nominal behaviour. Vice versa, one can also estimate the attitude states of the target by fitting the radar mappings to the observations. It has been demonstrated for the latter use case that a coarse approximation of the target through an 3D-model is already sufficient to derive the attitude information from the generated mappings. The level of detail required for the 3D-model is determined by the process of generating ISAR images, which is based on the theory of scattering bodies. Therefore, a complex surface can return an intrinsically noisy ISAR image. E.g. when many instruments on a satellite are visible to the observer, the ISAR image can suffer from multipath reflections. In this paper, we will further analyse the sensitivity of the attitude fitting algorithms to variations in the dimensions and the level of detail of the underlying 3D model. Moreover, we investigate the ability to estimate the orientations of different

  13. Kernkraftwerk Sued - the Wyhl decision of March 30, 1982/July 6, 1982

    1982-01-01

    This volume contains the complete Wyhl decision of the Higher Administrative Court of Baden-Wuerttemberg of March 30, 1982-X575/77, X578/77, X583/77 which cores 548 pages. According to the press release the complete decision has been delivered to the counsels of the parties to the lawsuit on July 7, 1983; on the appeal of the defendant Land and the attending Kernkraftwerk Sued GmbH the Higher Administrative Court has amended the decisions of the Administrative Court of Freiburg of March 14, 1977 and has rejected the actions of nine citizens against the first part construction permit. Moreover, the senate has sent to the parties to the lawsuit the decision of March 30, 1982, by which the value in dispute for these proceedings on appeal is fixed to DM 180,000. The time for the lodging of an appeal, which has been admitted by the senate in this process, begins with the delivery of the completely well-founded decision. Moreover, the volume contains a 10 pages summary of contents of the decision and a table of contents of the reasons for the decision. (orig./HSCH) [de

  14. Nuclear power plant Isar. Actualized environmental statement 2012 on the consolidated environmental statement 2010

    2012-01-01

    The actualized environmental statement 2012 for the NPP Isar covers the following issues: Direct environmental aspects: heat dissipation to the environment, water management, radioactive matter release onto the environment, environmental monitoring, waste management, operational materials supply, radioactive materials transport, safety of the nuclear facilities, remote monitoring and information system, environmental protection, communication; indirect environmental aspects; core indicators according EMAS III, development of the environmental targets and programs, reference to the valid environmental regulations, declaration of the environmental consultant.

  15. A Parasitic Array Receiver for ISAR Imaging of Ship Targets Using a Coastal Radar

    Fabrizio Santi

    2016-01-01

    Full Text Available The detection and identification of ship targets navigating in coastal areas are essential in order to prevent maritime accidents and to take countermeasures against illegal activities. Usually, coastal radar systems are employed for the detection of vessels, whereas noncooperative ship targets as well as ships not equipped with AIS transponders can be identified by means of dedicated active radar imaging system by means of ISAR processing. In this work, we define a parasitic array receiver for ISAR imaging purposes based on the signal transmitted by an opportunistic coastal radar over its successive scans. In order to obtain the proper cross-range resolution, the physical aperture provided by the array is combined with the synthetic aperture provided by the target motion. By properly designing the array of passive devices, the system is able to correctly observe the signal reflected from the ships over successive scans of the coastal radar. Specifically, the upper bounded interelement spacing provides a correct angular sampling accordingly to the Nyquist theorem and the lower bounded number of elements of the array ensures the continuity of the observation during multiple scans. An ad hoc focusing technique has been then proposed to provide the ISAR images of the ships. Simulated analysis proved the effectiveness of the proposed system to provide top-view images of ship targets suitable for ATR procedures.

  16. Use of Genetic Algorithms for Contrast and Entropy Optimization in ISAR Autofocusing

    Martorella Marco

    2006-01-01

    Full Text Available Image contrast maximization and entropy minimization are two commonly used techniques for ISAR image autofocusing. When the signal phase history due to the target radial motion has to be approximated with high order polynomial models, classic optimization techniques fail when attempting to either maximize the image contrast or minimize the image entropy. In this paper a solution of this problem is proposed by using genetic algorithms. The performances of the new algorithms that make use of genetic algorithms overcome the problem with previous implementations based on deterministic approaches. Tests on real data of airplanes and ships confirm the insight.

  17. Testing time for Siemens/KWU's PRINS/PRISCA at Isar II and Emsland

    Aleite, W.

    1988-01-01

    The culmination of work started in the early 1970s, the first PRINS/PRISCA process information system has recently been through commissioning tests at the new Isar II and Emsland convoy PWRS. PRINS/PRISCA is a human factor orientated, fully redundant, distributed, real time computer system with full graphic capabilities and standardized pictorial symbols. It also features elements of artificial intelligence and an innovative presentation of information, using banks of up to eight screens. KWU reports that reactions from operators have been increasingly positive. (author)

  18. Poolside fuel assembly inspection campaigns performed at Kernkraftwerk Leibstadt during summer 1997

    Zwicky, H.U.; Wiktor, C.G.; Schrire, D.

    1998-01-01

    In order to minimise fuel cycle costs, fuel assembly discharge burnup and average U-235 enrichment were increasing over past years in the Kernkraftwerk Leibstadt (KKL) plant. In parallel, high burnup verification programs were defined in collaboration with fuel suppliers. The aim of these programs is to demonstrate safe and reliable fuel performance up to the designed burnup limit and to identify any problems in due time. This is not only achieved by detailed poolside inspections of lead test assemblies, but also by hot cell post-irradiation examination of selected rods. In the frame of a hot cell examination campaign, enhanced localised corrosion in the vicinity of spacers on SVEA-96 fuel rods was identified in May 1997 as a potential problem. The average rod burnup of the investigated rods was around 50 MWd/kgU after 5 one year cycles of operation. As fuel operation up to six cycles is foreseen in KKLs fuel management plants, the risk of fuel failures caused by enhanced localised corrosion could not be excluded. An action plan was therefore developed in order to identify the root cause. Part of the action plan were two poolside inspection campaigns: 1. Visual inspection of 38 assemblies unloaded during refuelling outage 1996 after 5 cycles in operation. This campaign was performed in June 1997. It gave a broader data base to develop a concept for fuel management for the upcoming refuelling outage scheduled in August 1997. 2. Visual inspection, oxide layer thickness measurements, crud sampling and rod diameter measurements on 29 assemblies with different operation histories. This campaign was performed during the outage. A large portion of the inspected bundles was re-inserted for continued operation. The collected data confirmed that assumptions made for reload licensing and safety analyses were conservative. The inspection campaigns performed at KKL during summer 1997 by ABB Atom demonstrated that it is possible to address unexpected problems in a short time

  19. A signature correlation study of ground target VHF/UHF ISAR imagery

    Gatesman, Andrew J.; Beaudoin, Christopher J.; Giles, Robert H.; Kersey, William T.; Waldman, Jerry; Carter, Steve; Nixon, William E.

    2003-09-01

    VV and HH-polarized radar signatures of several ground targets were acquired in the VHF/UHF band (171-342 MHz) by using 1/35th scale models and an indoor radar range operating from 6 to 12 GHz. Data were processed into medianized radar cross sections as well as focused, ISAR imagery. Measurement validation was confirmed by comparing the radar cross section of a test object with a method of moments radar cross section prediction code. The signatures of several vehicles from three vehicle classes (tanks, trunks, and TELs) were measured and a signature cross-correlation study was performed. The VHF/UHF band is currently being exploited for its foliage penetration ability, however, the coarse image resolution which results from the relatively long radar wavelengths suggests a more challenging target recognition problem. One of the study's goals was to determine the amount of unique signature content in VHF/UHF ISAR imagery of military ground vehicles. Open-field signatures are compared with each other as well as with simplified shapes of similar size. Signatures were also acquired on one vehicle in a variety of configurations to determine the impact of monitor target variations on the signature content at these frequencies.

  20. Investigating the effect of a targets time-varying doppler generating axis of rotation on isar image distortion

    Abdul Gaffar, MY

    2007-10-01

    Full Text Available , contributes to ISAR image blurring. Quaternion algebra is used to aid the characterisation of a time-varying Doppler generating axis of rotation on the migration through cross-range cells. Real motion data of a sailing yacht is used to examine the effects of 3...

  1. Selecting suitable coherent processing time window lengths for ground-based ISAR imaging of cooperative sea vessels

    Abdul Gaffar, MY

    2009-09-01

    Full Text Available CPTWLs are needed for larger vessels in order to obtain ISAR images with the desired cross-range resolution. The effectiveness of the CPTWLs, suggested by the MACS algorithm, is shown using measured radar data. The suggested CPTWLs may also be used...

  2. The ring-stiffened shell of the ISAR II nuclear power plant natural-draught cooling tower

    Form, J.

    1986-01-01

    The natural-draught cooling tower of the ISAR II nuclear power plant is one of the largest in the world. The bid specifications provided for an unstiffened cooling tower shell. For the execution, however, it was decided to adopt a shell with three additional stiffening rings. The present contribution deals with the static and dynamic calculations of the execution and, in particular, with the working technique employed for the construction of the rings. (author)

  3. Tracking of Range and Azimuth for Continuous Imaging of Marine Target in Monopulse ISAR with Wideband Echoes

    Junhao Xie

    2016-01-01

    Full Text Available Real-time tracking of maneuvering targets is the prerequisite for continuous imaging of moving targets in inverse synthetic aperture radar (ISAR. In this paper, the range and azimuth tracking (RAT method with wideband radar echoes is first presented for a mechanical scanning monopulse ISAR, which is regarded as the simplest phased array unit due to the two antenna feeds. To relieve the estimation fluctuation and poor robustness of the RAT method with a single snapshot, a modified range and azimuth tracking approach based on centroid algorithm (RATCA with forgotten factor and multiple echoes is then proposed. The performances of different forgotten factors are investigated. Both theoretical analysis and experimental results demonstrate that RATCA is superior to RAT method. Particularly, when target echo is missing occasionally, RAT method fails while RATCA still keeps good performance. The potential of continuous imaging with shipborne ISAR is verified by experimental results. With minor modification, the method proposed in this paper can be potentially applied in the phased array radar.

  4. Probabilistic safety analysis for fire events for the NPP Isar 2

    Schmaltz, H.; Hristodulidis, A.

    2007-01-01

    The 'Probabilistic Safety Analysis for Fire Events' (Fire-PSA KKI2) for the NPP Isar 2 was performed in addition to the PSA for full power operation and considers all possible events which can be initiated due to a fire. The aim of the plant specific Fire-PSA was to perform a quantitative assessment of fire events during full power operation, which is state of the art. Based on simplistic assumptions referring to the fire induced failures, the influence of system- and component-failures on the frequency of the core damage states was analysed. The Fire-PSA considers events, which will result due to fire-induced failures of equipment on the one hand in a SCRAM and on the other hand in events, which will not have direct operational effects but because of the fire-induced failure of safety related installations the plant will be shut down as a precautionary measure. These events are considered because they may have a not negligible influence on the frequency of core damage states in case of failures during the plant shut down because of the reduced redundancy of safety related systems. (orig.)

  5. Supervised Self-Organizing Classification of Superresolution ISAR Images: An Anechoic Chamber Experiment

    Radoi Emanuel

    2006-01-01

    Full Text Available The problem of the automatic classification of superresolution ISAR images is addressed in the paper. We describe an anechoic chamber experiment involving ten-scale-reduced aircraft models. The radar images of these targets are reconstructed using MUSIC-2D (multiple signal classification method coupled with two additional processing steps: phase unwrapping and symmetry enhancement. A feature vector is then proposed including Fourier descriptors and moment invariants, which are calculated from the target shape and the scattering center distribution extracted from each reconstructed image. The classification is finally performed by a new self-organizing neural network called SART (supervised ART, which is compared to two standard classifiers, MLP (multilayer perceptron and fuzzy KNN ( nearest neighbors. While the classification accuracy is similar, SART is shown to outperform the two other classifiers in terms of training speed and classification speed, especially for large databases. It is also easier to use since it does not require any input parameter related to its structure.

  6. Micro-motion Recognition of Spatial Cone Target Based on ISAR Image Sequences

    Changyong Shu

    2016-04-01

    Full Text Available The accurate micro-motions recognition of spatial cone target is the foundation of the characteristic parameter acquisition. For this reason, a micro-motion recognition method based on the distinguishing characteristics extracted from the Inverse Synthetic Aperture Radar (ISAR sequences is proposed in this paper. The projection trajectory formula of cone node strong scattering source and cone bottom slip-type strong scattering sources, which are located on the spatial cone target, are deduced under three micro-motion types including nutation, precession, and spinning, and the correctness is verified by the electromagnetic simulation. By comparison, differences are found among the projection of the scattering sources with different micro-motions, the coordinate information of the scattering sources in the Inverse Synthetic Aperture Radar sequences is extracted by the CLEAN algorithm, and the spinning is recognized by setting the threshold value of Doppler. The double observation points Interacting Multiple Model Kalman Filter is used to separate the scattering sources projection of the nutation target or precession target, and the cross point number of each scattering source’s projection track is used to classify the nutation or precession. Finally, the electromagnetic simulation data are used to verify the effectiveness of the micro-motion recognition method.

  7. Research on spatial-variant property of bistatic ISAR imaging plane of space target

    Guo Bao-Feng; Wang Jun-Ling; Gao Mei-Guo

    2015-01-01

    The imaging plane of inverse synthetic aperture radar (ISAR) is the projection plane of the target. When taking an image using the range-Doppler theory, the imaging plane may have a spatial-variant property, which causes the change of scatter’s projection position and results in migration through resolution cells. In this study, we focus on the spatial-variant property of the imaging plane of a three-axis-stabilized space target. The innovative contributions are as follows. 1) The target motion model in orbit is provided based on a two-body model. 2) The instantaneous imaging plane is determined by the method of vector analysis. 3) Three Euler angles are introduced to describe the spatial-variant property of the imaging plane, and the image quality is analyzed. The simulation results confirm the analysis of the spatial-variant property. The research in this study is significant for the selection of the imaging segment, and provides the evidence for the following data processing and compensation algorithm. (paper)

  8. Joint Processing of Envelope Alignment and Phase Compensation for Isar Imaging

    Chen, Tao; Jin, Guanghu; Dong, Zhen

    2018-04-01

    Range envelope alignment and phase compensation are spilt into two isolated parts in the classical methods of translational motion compensation in Inverse Synthetic Aperture Radar (ISAR) imaging. In classic method of the rotating object imaging, the two reference points of the envelope alignment and the Phase Difference (PD) estimation are probably not the same point, making it difficult to uncouple the coupling term by conducting the correction of Migration Through Resolution Cell (MTRC). In this paper, an improved approach of joint processing which chooses certain scattering point as the sole reference point is proposed to perform with utilizing the Prominent Point Processing (PPP) method. With this end in view, we firstly get the initial image using classical methods from which a certain scattering point can be chose. The envelope alignment and phase compensation using the selected scattering point as the same reference point are subsequently conducted. The keystone transform is thus smoothly applied to further improve imaging quality. Both simulation experiments and real data processing are provided to demonstrate the performance of the proposed method compared with classical method.

  9. Decontamination of the reactor pressure vessel and further internals and auxiliary systems in the German boiling water reactor Isar-1; Dekontamination des RDB inkl. der Einbauten wie Dampftrockner und Wasserabscheider sowie der angeschlossenen Hilfssysteme im deutschen Siedewasserreaktor ISAR 1

    Fischer, Michael; Sempere Belda, Luis; Basu, Ashim; Topf, Christian [AREVA GmbH, Erlangen (Germany). Abt. Chemistry Services; Erbacher, Thomas; Hiermer, Thomas; Schnurr, Bernhard; Appeldorn, Thomas van [E.ON Kernkraft GmbH, Kernkraftwerk ISAR, Essenbach (Germany). Abt. Maschinentechnik; Volkmann, Christian [ESG Engineering Services GmbH, Greifswald (Germany)

    2015-12-15

    The German nuclear power plant ISAR 1 (KKI 1), a 878 MWe boiling water reactor of KWU design, was shut down on March 17{sup th}, 2011. With the objective to minimize the plants activity inventory accompanied by the reduction of contact dose rates of systems and components the project 'decontamination of the RPV incl. steam dryer and water separator and the connected auxiliary systems' was implemented in the first quarter of 2015. One major focus within the project was the specific in-situ decontamination of the steam dryer.

  10. Long-term prognostic value of risk scores after drug-eluting stent implantation for unprotected left main coronary artery: A pooled analysis of the ISAR-LEFT-MAIN and ISAR-LEFT-MAIN 2 randomized clinical trials.

    Xhepa, Erion; Tada, Tomohisa; Kufner, Sebastian; Ndrepepa, Gjin; Byrne, Robert A; Kreutzer, Johanna; Ibrahim, Tareq; Tiroch, Klaus; Valgimigli, Marco; Tölg, Ralf; Cassese, Salvatore; Fusaro, Massimiliano; Schunkert, Heribert; Laugwitz, Karl L; Mehilli, Julinda; Kastrati, Adnan

    2017-01-01

    To evaluate the long-term prognostic value of risk scores in the setting of drug-eluting stent (DES) implantation for uLMCA. Data on the prognostic value of novel risk scores developed to select the most appropriate revascularization strategy in patients undergoing DES implantation for uLMCA disease are relatively limited. The study represents a patient-level pooled analysis of the ISAR-LEFT-MAIN (607 patients randomized to paclitaxel-eluting or sirolimus-eluting stents) and the ISAR-LEFT-MAIN-2 (650 patients randomized to everolimus-eluting or zotarolimus-eluting stents) randomized trials. The Syntax Score (SxScore) as well the Syntax Score II (SS-II), the EuroSCORE and the Global Risk Classification (GRC) were calculated. The primary outcome was all-cause mortality. At a mean follow-up of 3 years there were 160 deaths (12.7%). The death-incidence was significantly higher in the upper tertiles than in the intermediate or lower ones for all risk scores (log-rank test P risk scores were able to stratify the mortality risk at long-term follow-up. EuroSCORE was the only risk score that significantly improved the discriminatory power of a multivariable model to predict long-term mortality. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  11. Synthetic range profiling, ISAR imaging of sea vessels and feature extraction, using a multimode radar to classify targets: initial results from field trials

    Abdul Gaffar, MY

    2011-04-01

    Full Text Available tanazi@kacst.edu.sa, aazamil@kacst.edu.sa Abstract?This paper describes the design and working principles of an experimental multimode radar with a stepped-frequency Synthetic Range Profiling (SRP) and Inverse Synthetic Aperture Radar (ISAR...

  12. Measures to assess and to assure the integrity of RPV-internals at Isar, Unit 1 Nuclear Power Plant

    Erve, M.; Bouecke, R.; Leibold, F.; Marschke, D.; Senski, G.; Maier, V.

    1998-01-01

    As visual examinations carried out in autumn 1994 detected cracks in a German BWR plant due to intergranular stress corrosion cracking in several core shroud components manufactured from 1.4550 steel, precautionary examinations and assessments were performed for all other plants. In accordance with these analyses, it can be stated for Isar, Unit 1 that the heat treatment to which the components in question were subjected in the course of manufacture cannot have caused sensitization of the material, and that crack formation due to the damage mechanism primarily identified in the reactor pressure vessel internals at Wuergassen Nuclear Power Station need not be feared. Although the material and corrosion-chemical assessments performed to date did not give any indications for the other crack formation mechanisms that are theoretically relevant for reactor pressure vessel internals (IGSCC due to weld sensitization, IASCC), visual examinations with a limited scope will be carried out with the independent expert's agreement during the scheduled inservice inspections. The fluid-dynamic and structure-mechanical analyses showed that the individual components are subjected only to low loadings, even in the event of accidents, and that the safety objectives shutdown and residual heat removal can be fulfilled even in the case of large postulated cracks. The fracture-mechanics analyses indicated critical through-wall crack lengths which, however, can be promptly and reliably detected during random inservice inspections even when assuming stress corrosion cracking and irradiation-induced low-toughness material conditions. In addition, both the VGB and the Isar, Unit 1 licensee are pursuing further prophylactic measures such as alternative water chemistry modes and an appropriate repair and replacement concept. (author)

  13. Emergency planning of the city of Munich with reference to nuclear facilities, especially the nuclear power stations Isar I and II, resp. the reactor in Garching

    1990-01-01

    During the hearing of Munich's city council of 13.7.1990 thirteen experts were heard on the following subjects: Hazard potential of Isar reactors and FRM reactor and appropriate radioactive waste transports; responsibilities in emergency planning. Some of the experts cannot visualize a major accident and propose not to cater for it. Shelters and evacuation are not planned for Munich, both solutions not being realizable for all inhabitants. Nuclear phaseout is seen by some as a measure of prevention. (HSCH) [de

  14. Investigation of sensors and instrument components in boiling water reactors. Results from Oskarshamn 2, Barsebaeck 2 in Sweden and Kernkraftwerk Muehleberg in Switzerland

    Bergdahl, B.G.

    1998-05-01

    The reactor monitoring instruments are important for the operation and safety of the plants. Static properties of the instruments are controlled annually, but the dynamic properties are rarely, if ever, examined. This study is the result of a project initiated by the Swedish Nuclear Power Inspectorate. The examinations are based on signal analysis and simultaneous measurement of multiple signals. Results from Oskarshamn 2 (O2), Barsebaeck 2 (B2) and Kernkraftwerk Muehleberg (KKM) are discussed in this report. The presentation is focused on reactor pressure and reactor level signals. the analysis of O2 revealed that the dynamics for 3 out of 14 sensors was 'filtered', meaning that a rapid level displacement is registered with delay. Inspection showed that a 1 sec filter was installed instead of 1.2 sec. The study also showed that old pressure-sensors in use both at O2 and B2 could not cope with high frequencies, and that some level-sensors were disturbed by mechanical oscillations at Bw. At KKM, a 2 Hz resonance was observed with 12 pressure and level sensors. The oscillation was created by an old pressure sensor and influenced the other sensors through the common impulse network

  15. Influence on components of EU directives; Einfluss von EG-Richtlinien auf Komponenten. Einfluss der EG-Druckgeraeterichtlinie (97/23/EG) auf die Komponenten eines Kernkraftwerks vom Typ Konvoi

    Kreckel, D. [Siemens AG, Bereich Energieerzeugung (KWU), Offenbach (Germany)

    1998-11-01

    Convoy-type nuclear power plant maintenance is subject to the specifications contained in the Technical Rules, as dated in the Annex, on the basis of the operating permits issued under Sec. 7 of the German Atomic Energy Act. The introduction of the Single European Market and the adoption of European directives in the field of equipment safety have influenced, and will continue to influence, the national legislative structure. Changes affecting convoy-type nuclear power plants can be found in the applicable laws and directives, such as the Atomic Energy Act, the Industrial Code, and in new regulations, such as the Equipment Safety Act with its associated ordinances, and the applicable engineered safeguards rules, such as KTA, AD, VdTUeV, VDI. Moreover, the generally recognized state of the art as laid down in DIN, SEL, SEW publications is subject to permanent European harmonization and, consequently, comprehensive national reorganization. These boundary conditions can be upheld only if the specifications about the advancing state of the art specified in the operating permits are put into effect painstakingly. The profile of requirements contained in these specifications must be aligned to the new situation in Germany (dominated by Europe) with the licensing authority and the competent expert consultant within the supervisory procedure for operation under the Atomic Energy Act. The situation described here for the modern convoy-type nuclear power plants must be extrapolated also to older nuclear power plants, albeit subject to a supplementary adaptation to the respective licensing situation. (orig.) [Deutsch] Fuer die Instanhaltung der Konvoi-Kernkraftwerke gelten die Spezifikationen mit dem in den Anhaengen datierten Stand der Technischen Regeln gemaess der auf Basis des AtG Paragraph 7 erteilten Betriebsgenehmigungen. Mit der Einfuehrung des Europaeischen Binnenmarktes und Verabschiedung Europaeischer Richtlinien auf dem Sektor der Geraetesicherheit wurde und wird

  16. Identification of seniors at risk (ISAR) screening tool in the emergency department: implementation using the plan-do-study-act model and validation results.

    Asomaning, Nana; Loftus, Carla

    2014-07-01

    To better meet the needs of older adults in the emergency department, Senior Friendly care processes, such as high-risk screening are recommended. The identification of Seniors at Risk (ISAR) tool is a 6-item validated screening tool for identifying elderly patients at risk of the adverse outcomes post-ED visit. This paper describes the implementation of the tool in the Mount Sinai Hospital emergency department using a Plan-Do-Study-Act model; and demonstrates whether the tool predicts adverse outcomes. An observational study tracked tool implementation. A retrospective chart audit was completed to collect data about elderly ED patients during 2 time periods in 2010 and 2011. Data analysis compared the characteristics of patients with positive and negative screening tool results. The identification of Seniors at Risk tool was completed for 51.6% of eligible patients, with 61.2% of patients having a positive result. Patients with positive screening results were more likely to be over age 79 (P = .003); be admitted to hospital (P Risk tool was challenged by problematic compliance with tool completion. Strategies to address this included tool adaptation; and providing staff with knowledge of ED and inpatient geriatric resources and feedback on completion rates. Positive screening results predicted adverse outcomes in elderly Mount Sinai Hospital ED patients. © 2014. Published by Elsevier Inc. All rights reserved.

  17. UMA ANÁLISE CRÍTICA ENTRE OS CURRÍCULOS DOS CURSOS DE CIÊNCIAS CONTÁBEIS NOS PAÍSES DO MERCOSUL E O PROPOSTO PELA ONU/UNCTAD/ISAR

    Giovanna Tonetto Segantini

    2013-07-01

    Full Text Available A harmonização das normas contábeis tornou-se uma necessidade dos usuários externos e in-ternos da informação contábil, uma vez que passaram a atuar em diversos mercados e a prestar contas aos usuários com necessidades variadas, pois o mercado cada vez mais globalizado exige profissionais preparados para atuar dentro e fora do seu país. Visando isso, a ONU/UNCTAD/ISAR desenvolveu um Currículo Mundial para servir de referência para os cursos de Ciências Contábeis, buscando prover conhecimentos internacionais de normas contábeis independentemente do país responsável pela formação do profissional. Assim, o objetivo geral do artigo foi analisar e comparar a adequação dos currículos dos cursos de ciências contá-beis de quatro universidades do MERCOSUL, sendo uma de cada país, com o currículo proposto pela ONU/UNCTAD/ISAR. As universidades selecionadas foram: Facultad de Ciencias Econômicas de la Universidad de Buenos Aires (Argentina; Faculdade de Economia, Administração e Con-tabilidade da Universidade de São Paulo (Brasil; Universidad Nacional de Asunción (Paraguai; e Facultad de Ciências Econômicas y de Administración de la Universidad de la República (Uruguai, e suas matrizes curriculares foram comparadas com o Currículo Mundial proposto pela ONU/UNCTAD/ISAR. Os resultados indicam que a similaridade entre os currículos das quatro universidades selecionadas com o proposto pela ONU/UNCTAD/ISAR é alta, existindo, em mé-dia, 76,71% de semelhança entre as matérias dos currículos. Por ser apenas uma recomendação, as universidades pesquisadas demonstraram possuir certa flexibilidade na elaboração de seus currículos.

  18. Uma Análise Crítica Entre os Currículos dos Cursos de Ciências Contábeis nos Países do Mercosul e o Proposto Pela ONU/UNCTAD/ISAR

    Giovanna Tonetto Segantini

    2013-07-01

    Full Text Available A harmonização das normas contábeis tornou-se uma necessidade dos usuários externos e internos da informação contábil, uma vez que passaram a atuar em diversos mercados e a prestar contas aos usuários com necessidades variadas, pois o mercado cada vez mais globalizado exige profissionais preparados para atuar dentro e fora do seu país. Visando isso, a ONU/UNCTAD/ISAR desenvolveu um Currículo Mundial para servir de referência para os cursos de Ciências Contábeis, buscando prover conhecimentos internacionais de normas contábeis independentemente do país responsável pela formação do profissional. Assim, o objetivo geral do artigo foi analisar e comparar a adequação dos currículos dos cursos de ciências contábeis de quatro universidades do MERCOSUL, sendo uma de cada país, com o currículo proposto pela ONU/UNCTAD/ISAR. As universidades selecionadas foram: Facultad de Ciencias Econômicas de la Universidad de Buenos Aires (Argentina; Faculdade de Economia, Administração e Contabilidade da Universidade de São Paulo (Brasil; Universidad Nacional de Asunción (Paraguai; e Facultad de Ciências Econômicas y de Administración de la Universidad de la República (Uruguai, e suas matrizes curriculares foram comparadas com o Currículo Mundial proposto pela ONU/UNCTAD/ISAR. Os resultados indicam que a similaridade entre os currículos das quatro universidades selecionadas com o proposto pela ONU/UNCTAD/ISAR é alta, existindo, em média, 76,71% de semelhança entre as matérias dos currículos. Por ser apenas uma recomendação, as universidades pesquisadas demonstraram possuir certa flexibilidade na elaboração de seus currículos.

  19. Temporary provision against Kernkraftwerk Biblis dismissed

    Anon.

    1980-01-01

    With its decision of November 19, 1979 - VIII IG 13/79 -, the Administrative Court of Hesse has refused the complaint of a Darmstadt resident whose application for a temporary provision interdicting further operation of the power plant units Biblis A and B had been refused by the Darmstadt Administrative Court. The costs of the procedure, including the extra-judicial costs of the witnesses heard, are to be paid by the plaintiff. The value in litigation was raised to DM 10 000,-. (orig./HP) 891 HP/orig.- 892 CKA [de

  20. Expert report of ENSI on the request of KKN AG for a general license - Project 'New nuclear power plant Niederamt'; Gutachten des ENSI zum Rahmenbewilligungsgesuch der KKN AG. Neubauprojekt Kernkraftwerk Niederamt

    NONE

    2010-09-15

    The 'Kernkraftwerk Niederamt AG' (KKN) Company submitted to the Swiss Federal Inspectorate of Nuclear Safety (ENSI) a request for a general license for a new power plant to be built near to the Goesgen power plant. According to the law, all damage risks with a probability higher than 10{sup -4}/a must be taken into account through protection measures. The considered risks concern the power plant itself as well as the population in the neighbourhood and the environment. The purpose of the general license is to demonstrate that the site chosen for the foreseen power plant is acceptable and that the risks can be counteracted through adequate measures. The buildings of the power plant and their partition over the two banks of the Aare River are briefly described. The reactor is a Light Water Reactor of third generation with a maximum thermal power of 5.8 GW{sub th}. The main cooling is provided by a hybrid system of water evaporation and air heating, what reduces the plume at the exit of the cooling tower. First, it is demonstrated that, in the case of a very unlikely severe accident in the power plant, the people in the neighbourhood can be evacuated quickly. Then, numerous types of possible accidents in the neighbourhood of the power plant are analyzed in order to settle their possible negative influence on the operation of the power plant: bursting of gas containers on the neighbouring roads and railways, fires of all types of hydrocarbons, air pollution through chloride gas, etc. The check by ENSI of the KKN studies on the potential danger for the power plant through neighbouring industrial plants, roads or railways demonstrated that none of the considered accidents presents an unacceptable risk for the power plant: on the one hand, these plants are located too far from the power plant, so that a sensible injury to the power plant safety can be excluded; on the other, the protection of the power plant can be guaranteed through appropriate technical

  1. Hochtemperatur-Kernkraftwerk GmbH (HKG). Annual report 1985

    1986-01-01

    The annual report presents the agenda of the general meeting of members, held on July 3, 1986 at Hamm-Uentrop, the report of the managing board, and the annual financial statement as of December 31, 1985, including the profit and loss account of the period January 1 to December 31, 1985. The object of the HKG GmbH is the planning, financing, installation, and operation of the Hamm-Uentrop nuclear power station equipped with a high-temperature reactor, as a joint enterprise of the European partners. (UA) [de

  2. Publication concerning licensing notices for the Kernkraftwerk Kruemmel

    1977-01-01

    The 3rd supplement to the 2nd partial licence sector concerns the change of concept regarding the scram system by going over from the scram collecting tank system to the individual tank system. The 7th partial licence notice refers to the construction of 1) the control rod drive and the scram system including the related operational controls; 2) the emergency power diesel aggregates; 3) the condensation pipe transverse system (transverse system in the condensation chamber). (orig./HP) [de

  3. Kernkraftwerk Obrigheim (KWO) GmbH. Annual report 1991

    Koerner, C.

    1992-01-01

    The Obrigheim nuclear power station was operated at full load from August 21 through Dec. 31, 1991, generating 1.108 GWh of electrical energy in 3.186 operating hours. The Obrigheim nuclear power station thus achieved during this period of 133 days in 1991 an operating availability of 100%. Since its commissioning in October 1968, the Obrigheim reactor station has been operating for 161.527 hours, generating 54.409 GWh (gross), and from test operation started in March 1969 up to the end of 1991, all in all 54.284 GWh have been generated in 160.747 operating hours, which means an availability time ratio of 78.2%, and a capacity factor of 80.4%. The plant was shut down in 1991 for the 21st refuelling operation including inspection and repair work, for a fictitious period of 1783 hours. In addition, power operation was stopped by an order of the supervisory authority for another 3.791 hours, so that the plant remained disconnected from the grid between Januar 1 and August 8, 1991. In the last part of the year 1991, until May 26, the plant had an excellent availability time ratio and thus contributed about 2.5% of the safe, economic and environmentally sound electricity supplies in Baden-Wuerttemberg. (orig.) [de

  4. Kernkraftwerk Obrigheim GmbH. Annual report 1989

    Koerner, C.

    1990-01-01

    The Obrigheim nuclear power station was operated at full load during the year 1989: 7.756 operating hours produced electrical energy of 2.689 GWh. This is the fifth best annual result during Obrigheim's operating period. Since commissioning in October 1968, 154.866 hours of operation have generated 52.125 GWh (gross) and from test operation in March 1969 until the end of 1989, 154.086 hours of operation have generated 52.013 GWh. This is an availability of power of 82.1% in this period and a time availability of 84.4%. In 1988, the plant was shut down for 927 hours for the 20th refueling including testing, inspection and repair work. Apart from refueling, the plant had a good time availability and therefore contributed 5% to the safe, economical and environmentally acceptable electricity supply of the Land Baden-Wuerttemberg. The power station is of great significance to the region, both in terms of power supply and the economy. (orig.) [de

  5. Annual report 1988 of the Kernkraftwerk Obrigheim GmbH

    Koerner, C.

    1989-01-01

    The Obrigheim nuclear power station was operated at full load during the year 1988; 7.800 operating hours produced electrical energy of 2.755 GWh. This is the second best annual result during Obrigheim's operating period. Since commissioning in October 1968, 147.110 hours of operation have generated 49.436 GWh (gross) and from test operation in March 1969 until the end of 1988, 146.330 hours of operation have generated 49.324 GWh. This is an availability of power of 81.9% in this period and a time availability of 84.1%. In 1988, the plant was shut down for 927 hours for the 18th refueling including testing, inspection and repair work. Apart from refueling, the plant had a good time availability and therefore contributed 5% to the safe, economical and environmentally acceptable electricity supply of the Land Baden-Wuerttemberg. The power station is of great significance to the region, both in terms of power supply and the economy. (orig./HP) [de

  6. Kernkraftwerk Obrigheim GmbH. Annual report 1990

    Koerner, C.

    1991-01-01

    The Obrigheim nuclear power station was operated at full load from January 1 through May 25, 1990, generating 1.236 GWh of electrical energy in 3.475 operating hours. The Obrigheim nuclear power station thus achieved during this period of 145 days in 1990 an operating availability of 100%. Since its commissioning in October 1968, the Obrigheim reactor station has been operating for 158.341 hours, generating 53.361 GWh (gross), and from test operation started in March 1969 up to the end of 1990, all in all 53.249 GWh have been generated in 157.561 operating hours, which means an availability time ratio of 82.3 %, and a capacity factor of 80.1%. The plant was shut down in 1990 for the 21st refuelling operation including inspection and repair work, for a fictitious period of 942 hours. In addition, power operation was stopped by an order of the supervisory authority for another 4.343 hours, so that the plant remained disconnected from the grid between May 26 and December 31, 1990. In the first part of the year 1990, until May 26, the plant had an excellent availability time ratio and thus contributed about 2.5% of the safe, economic and environmentally sound electricity supplies in Baden-Wuerttemberg. (orig./HP) [de

  7. Exploitation of ISAR Imagery in Euler Parameter Space

    Baird, Christopher; Kersey, W. T; Giles, R; Nixon, W. E

    2005-01-01

    .... The Euler parameters have potential value in target classification but have historically met with limited success due to ambiguities that arise in decomposition as well as the parameters' sensitivity...

  8. Safety culture in nuclear power plants. Proceedings; Sicherheitskultur im Kernkraftwerk. Seminarbericht

    NONE

    1994-12-01

    As a consequence of the INSAG-4 report on `safety culture`, published by the IAEA in 1991, the Federal Commission for the Safety of Nuclear Power Plants (KSA) decided to hold a one-day seminar as a first step in this field. The KSA is an advisory body of the Federal Government and the Federal Department of Transport and Energy (EVED). It comments on applications for licenses, observes the operation of nuclear power plants, assists with the preparation of regulations, monitors the progress of research in the field of nuclear safety, and makes proposals for research tasks. The objective of this seminar was to familiarise the participants with the principles of `safety culture`, with the experiences made in Switzerland and abroad with existing concepts, as well as to eliminate existing prejudices. The main points dealt with at this seminar were: - safety culture from the point of view of operators, - safety culture from the point of view of the authorities, - safety culture: collaboration between power plants, the authorities and research organisations, - trends and developments in the field of safety culture. Invitations to attend this seminar were extended to the management boards of companies operating Swiss nuclear power plants, and to representatives of the Swiss authorities responsible for the safety of nuclear power plants. All these organisations were represented by a large number of executive and specialist staff. We would like to express our sincerest thanks to the Head of the Federal Department of Transport and Energy for his kind patronage of this seminar. (author) figs., tabs., refs.

  9. Kernkraftwerke Lippe-Ems GmbH (KLE). 1995 annual report

    1996-01-01

    The tasks and activities of the operators of the Emsland reactor station (KKE) are reported. The year-end statement of 1995 includes many details about the financial situation, (such as the balance sheet, profit and loss account, etc.). (UA) [de

  10. KWL Lingen nuclear plant. Technical annual report 2016; KWL Kernkraftwerk Lingen. Technischer Jahresbericht 2016

    NONE

    2017-07-01

    The technical annual report 2016 for KWL (Lingen nuclear plant) covers the following sections: dismantling project management and operation, monitoring and clearance; waste management, technical qualification, security and safety, central tasks; licensing and supervision procedures, operational data, radiation monitoring, radioactive materials, in-service inspections.

  11. Impact of external grid disturbances on nuclear power plants; Rueckwirkungen von Netzstoerungen auf Kernkraftwerke

    Arains, Robert; Arnold, Simone; Brueck, Benjamin; Mueller, Christian; Quester, Claudia; Sommer, Dagmar

    2017-06-15

    The electrical design of nuclear power plants and the reliability of their electrical power supply including the offsite power supply are of high importance for the safe operation of the plants. The operating experience of recent years has shown that disturbances in the external grid can have impact on the electrical equipment of nuclear power plants. In the course of this project, possible causes and types of grid disturbances were identified. Based on these, scenarios of grid disturbances were developed. In order to investigate the impact of the developed scenarios of grid disturbances on the electrical equipment of nuclear power plants, the auxiliary power supply of a German pressurized water reactor of type Konvoi was simulated using the simulation tool NEPLAN. On the basis of the results of the analyses, it was identified whether there are possible measures to prevent the spread of grid disturbances in the plants which have not been implemented in the nuclear power plants today.

  12. On the safety of French nuclear power plants. Zur Sicherheit der franzoesischen Kernkraftwerke

    Anon,

    1990-04-01

    An allegedly secret report by the inspector general for nuclear safety, of EDF, has recently been unearthed and published by the French weekly 'Le Canard Enchaine, and the response in France, and very soon after also in West Germany, has been a number of alarming reports and articles in the press. Readers in West Germany have been stirred up by press reports that made French nuclear power plants appear to be a herd of hazards, which of course again added fuel to the feeling of fear of nuclear power already existing in the population. A copy of the internal report in question was sent without any fuss upon request by the atw editorial office who was preparing the interview. The report is a sober account of the state and operating behaviour of French nuclear power plants, also stating weak points seen by the safety expert that need particular attention. Materials are a main aspect in this context, particularly the materials behaviour in steam raising units. The problems have been spotted, and are given due attention. (orig./HP).

  13. Terahertz Inverse Synthetic Aperture Radar (ISAR) Imaging With a Quantum Cascade Laser Transmitter

    2010-01-01

    shown in Fig. 3 as compared to the frequency stability of the locked THz QCL, reported in Ref. 13. However, phase noise is not only a consequence of...a) photograph of a Boston Marathon medal, (b) 2.4 THz az/el image of the medal. The words “Boston Athletic Association” and the unicorn are well

  14. Coherent change detection and interferometric ISAR measurements in the folded compact range

    Sorensen, K.W.

    1996-08-01

    A folded compact range configuration has been developed ant the Sandia National Laboratories` compact range antenna and radar-cross- section measurement facility as a means of performing indoor, environmentally-controlled, far-field simulations of synthetic aperture radar (SAR) measurements of distributed target samples (i.e. gravel, sand, etc.). The folded compact range configuration has previously been used to perform coherent-change-detection (CCD) measurements, which allow disturbances to distributed targets on the order of fractions of a wavelength to be detected. This report describes follow-on CCD measurements of other distributed target samples, and also investigates the sensitivity of the CCD measurement process to changes in the relative spatial location of the SAR sensor between observations of the target. Additionally, this report describes the theoretical and practical aspects of performing interferometric inverse-synthetic-aperture-radar (IFISAR) measurements in the folded compact range environment. IFISAR measurements provide resolution of the relative heights of targets with accuracies on the order of a wavelength. Several examples are given of digital height maps that have been generated from measurements performed at the folded compact range facility.

  15. Bistatic SAR/ISAR/FSR geometry, signal models and imaging algorithms

    Lazarov, Andon Dimitrov

    2013-01-01

    Bistatic radar consists of a radar system which comprises a transmitter and receiver which are separated by a distance comparable to the expected target distance. This book provides a general theoretical description of such bistatic technology in the context of synthetic aperture, inverse synthetic aperture and forward scattering radars from the point of view of analytical geometrical and signal formation as well as processing theory. Signal formation and image reconstruction algorithms are developed with the application of high informative linear frequency and phase code modulating techniques

  16. Marine ARM GPCI Investigation of Clouds Infrared Sea Surface Temperature Autonomous Radiometer (ISAR) Field Campaign Report

    Reynolds, R. Michael [Remote Measurements & Research Company, Seattle, WA (United States); Long, Charles N. [National Oceanic and Atmospheric Administration (NOAA), Boulder, CO (United States). Earth System Research Lab.

    2016-01-10

    Sea surface temperature (SST) is one of the most appropriate and important climate parameters: a widespread increase is an indicator of global warming and modifications of the geographical distribution of SST are an extremely sensitive indicator of climate change. There is high demand for accurate, reliable, high-spatial-and-temporal-resolution SST measurements for the parameterization of ocean-atmosphere heat, momentum, and gas (SST is therefore critical to understanding the processes controlling the global carbon dioxide budget) fluxes, for detailed diagnostic and process-orientated studies to better understand the behavior of the climate system, as model boundary conditions, for assimilation into climate models, and for the rigorous validation of climate model output. In order to achieve an overall net flux uncertainty < 10 W/m2 (Bradley and Fairall, 2006), the sea surface (skin) temperature (SSST) must be measured to an error < 0.1 C and a precision of 0.05 C. Anyone experienced in shipboard meteorological measurements will recognize this is a tough specification. These demands require complete confidence in the content, interpretation, accuracy, reliability, and continuity of observational SST data—criteria that can only be fulfilled by the successful implementation of an ongoing data product validation strategy.

  17. Materials for the field test - students' attitudes to nuclear power stations. Materialien zum Unterrichtsversuch: Kernkraftwerke in der Einstellung von Jugendlichen

    Hoffmann, L; Kattmann, U; Lucht, H; Spada, H [Kiel Univ. (Germany, F.R.). Inst. fuer die Paedagogik der Naturwissenschaften (IPN)

    1975-01-01

    This working paper contains all the materials developed for and used in the field test of 'Student Attitudes toward Atomic Power Stations'. This research is a component of a larger project called 'Attitudes and Attitudes Change with Regard to Problems of Energy Supply and their Consequences for our Environment'. A central aim of this project is the development of instrumental strategies enabling the student to build up in this field a critically reflective and active behavior and attitudes based on sound problem consciousness. These instrumental strategies are derived from theories of social, learning and environmental psychology. A concrete result of these efforts are the materials of the field test mentioned above. They include: a) The draft of an instructional unit 'Atomic Power Stations - Prosperity or Disaster' with - a booklet on the subject matter for students and teachers - a paper on the contents of the instructional unit and their sequence - information for the students concerning the aims of the investigation - working materials for the students - reading materials for the teachers informing them about the proposed instructional strategies based on the psychological theories: (1) model-learning and the structuring of knowledge, (2) how to activate and motivate students, (3) the stabilization of attitudes and (4) small group work. b) Instruments for testing and observation. These instruments were used within a criterion-oriented evaluation and for a test of the effects of the different proposed items used in the instruction.

  18. Source Term Analysis for the Nuclear Power Station Goesgen-Daeniken; Quelltermanalysen fuer das Kernkraftwerk Goesgen-Daeniken

    Hosemann, J.P.; Megaritis, G.; Guentay, S.; Hirschmann, H.; Luebbesmeyer, D.; Lieber, K.; Jaeckel, B.; Birchley, J.; Duijvestijn, G

    2001-08-01

    Analyses are performed for three accident scenarios postulated to occur in the Goesgen Nuclear Power Plant, a 900 MWe Pressurised Water Reactor of Siemens design. The scenarios investigated comprise a Station Blackout and two separate cases of small break loss-of-coolant accident which lead, respectively, to high, intermediate and low pressure conditions in the reactor system. In each case the accident assumptions are highly pessimistic, so that the sequences span a large range of plant states and a damage phenomena. Thus the plant is evaluated for a diversity of potential safety challenges. A suite of analysis tools are used to examine the reactor coolant system response, the core heat-up, melting, fission product release from the reactor system, the transport and chemical behaviour of those fission products in the containment building, and the release of radioactivity (source term) to the environment. Comparison with reference values used by the licensing authority shows that the use of modern analysis tools and current knowledge can provide substantial reduction in the estimated source term. Of particular interest are insights gained from the analyses which indicate opportunities for operators to reduce or forestall the release. (author)

  19. German risk study on nuclear power plants. Appendix 2. Reliability analysis. Deutsche Risikostudie Kernkraftwerke. Fachband 2: Zuverlaessigkeitsanalyse

    Dietlmeier, W.; Gossner, S.; Gueldner, W.; Hoertner, H.; von Linden, J.; Preischl, W.; Reichart, G.; Spindler, H.; Volmer, G.; Zipf, G.

    1981-01-01

    Based on the event tree analysis as documented in the Appendix 1, the failure probabilities of the system functions required to control the initiating events are evaluated in this Appendix 2. The reliability investigations necessary for the evaluation of the event sequences are performed mostly by means of the fault tree analysis. The methods of the reliability analysis, the composition and function of the systems important to safety and the functional tests performed on these systems are dealt with in detail. The comprehensive documentation of the reliability analyses as performed for the internal events necessitated a division of this Appendix 2 into two volumes.

  20. Advanced handbook for accident analyses of German nuclear power plants; Weiterentwicklung eines Handbuches fuer Stoerfallanalysen deutscher Kernkraftwerke

    Kerner, Alexander; Broecker, Annette; Hartung, Juergen; Mayer, Gerhard; Pallas Moner, Guim

    2014-09-15

    The advanced handbook of safety analyses (HSA) comprises a comprehensive electronic collection of knowledge for the compilation and conduction of safety analyses in the area of reactor, plant and containment behaviour as well as results of existing safety analyses (performed by GRS in the past) with characteristic specifications and further background information. In addition, know-how from the analysis software development and validation process is presented and relevant rules and regulations with regard to safety demonstration are provided. The HSA comprehensively covers the topic thermo-hydraulic safety analyses (except natural hazards, man-made hazards and malicious acts) for German pressurized and boiling water reactors for power and non-power operational states. In principle, the structure of the HSA-content represents the analytical approach utilized by safety analyses and applying the knowledge from safety analyses to technical support services. On the basis of a multilevel preparation of information to the topics ''compilation of safety analyses'', ''compilation of data bases'', ''assessment of safety analyses'', ''performed safety analyses'', ''rules and regulation'' and ''ATHLET-validation'' the HSA addresses users with different background, allowing them to enter the HSA at different levels. Moreover, the HSA serves as a reference book, which is designed future-oriented, freely configurable related to the content, completely integrated into the GRS internal portal and prepared to be used by a growing user group.

  1. Dismantling the activated annular water tank of the Rheinsberg nuclear power plant; Zerlegung des aktivierten Ringwasserbehaelters des Kernkraftwerks Rheinsberg

    Klietz, Maik; Konitzer, Arnold; Luedeke, Michael [Anlagen- und Kraftwerksrohrleitungsbau GmbH, Greifswald (Germany)

    2010-10-15

    Acting on behalf of Energiewerke Nord GmbH Lubmin, Anlagen- und Kraftwerksrohrleitungsbau Greifswald GmbH (AKB) planned and built a station for disassembly of the activated annular water tank (RWB) of the decommissioned Rheinsberg nuclear power plant. As part of this demolition step, the annular water tank must be conditioned and disposed of as a component of the reactor facility. This required planning, manufacturing, testing and construction on site of suitable disassembly and handling techniques and the necessary plant and equipment. The client opted for disassembly by means of a diamond cable saw for conditioning the annular water tank into segments fit for shipping, and defined the basic components for the disassembly station in a specification of deliveries and services. The disassembly station serves to divide the annular water tank by means of diamond cable saws into 2 sections in such a way that segment pieces for transport are produced. The existing activation of the annular water tank also entailed the need to plan for the shortest possible time to be spent on handling near the annular water tank, providing radiological protection to the personnel, and performing the sawing steps from a separate operating console assisted by camera surveillance. After works acceptance tests at the manufacturer's, AKB, in October 2009 and February 2010, the disassembly station was delivered to the customer at Rheinsberg KKR free from defects in June 2010. (orig.)

  2. Harmonisation of licensing processes for decommissioning. Options and limitations; Genehmigungsverfahren fuer die Stilllegung der deutschen Kernkraftwerke. Konvoi oder Kakophonie?

    Raetzke, Christian

    2016-03-15

    The shutdown of eight reactors in Germany in the wake of Fukushima 2011 and the scheduled phase-out of the remaining units in several steps ending 2022 has obviously triggered a wave of applications for decommissioning and dismantling licences. It would seem natural to strive for a harmonised handling of these processes, analogous to the 'convoi' concept which was successfully employed for licensing and construction of the three most recent German NPPs in the 1980s. However, a comparative analysis shows that the motivation of all players is much different from that of earlier times and that harmonisation of licensing processes for dismantling is not as crucial for operators, authorities and technical support organisations as it was for construction.

  3. VGH Mannheim: legitimacy of the decommissioning license for a nuclear power plant; VGH Mannheim: Rechtmaessigkeit der Stilllegungsgenehmigung fuer ein Kernkraftwerk

    Anon.

    2015-03-16

    The contribution describes the details of the court (VGH) decision on the legitimacy of the decommissioning license for the NPP Obrigheim. Inhabitants of the neighborhood (3 to 4.5 km distance from the NPP) are suspect hazards for life, health and property due to the dismantling of the nuclear power plant in case of an accident during the licensed measures or a terroristic attack with radioactive matter release.

  4. Fifty years of Erlangen radiochemistry

    Morell, W.

    2007-01-01

    On June 29, 2006, the Radiochemical Laboratory of AREVA NP GmbH (formerly Siemens AG) in Erlangen celebrated its fiftieth anniversary. The occasion was marked by an event attended by more than 1,000 guests, among them Werner Gebauhr, the 85-year-old founder and first head of the Laboratory; the Managing Directors of AREVA NP GmbH, Ralf Gueldner and Ruediger Steuerlein; representatives of universities, research institutions, power utilities, and public authorities. The present head of the Radiochemical Laboratory, Wilfred Morell, sketched the highlights of the work performed over the past fifty years, which ranged from solid-state and very-high-purity materials technologies to development and service activities for nuclear technology. Manfred Erve, head of the Technical Center of AREVA NP GmbH, of which the Radiochemical Laboratory is a part, emphasized the changes in priorities over the past fifty years, which had always been met successfully by Radiochemistry. In the scientific part of the event, Wolfgang Schwarz (E.ON Kernkraftwerk GmbH, KKW Isar), Ulf Ilg (EnBW Kraftwerk AG, KKW Philippsburg), and Hans-Josef Allelein (Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH) explained 3 major subject areas in which Erlangen Radio-chemistry over many years has contributed basic findings (see other articles in this atw issue). On the occasion of the anniversary, a comprehensive booklet was published under the title of '50 Jahre Radiochemie Erlangen - 1956-2006'. (orig.)

  5. Hypofractionated stereotactic body radiotherapy (SBRT) for liver metastases. A retrospective analysis of 74 patients treated in the Klinikum rechts der Isar Munich; Die hypofraktionierte, stereotaktische Strahlentherapie von Lebermetastasen. Eine retrospektive Analyse von 74 Patienten des Klinikums rechts der Isar Muenchen

    Heppt, Franz Johannes

    2013-06-12

    Purpose of this study was to evaluate the outcome of stereotactic body radiotherapy (SBRT) of liver metastases and prognostic factors for local control and overall survival. From 2000 to 2009 74 patients with 91 metastases were treated at the Department for Radiation Therapy and Oncology (TU Muenchen). With an observed local control rate of 75% after 1 year, SBRT proved as an effective local treatment option. Unfortunately, systemic tumor progression still dominates long term survival in many patients.

  6. identification of banana varieties with resistance to nematodes in ...

    jen

    Institut des Sciences Agronomiques du Rwanda (ISAR), ISAR-Kibungo, Ngoma district, Rwanda ... for sustainable nematode management. Previous studies ..... Technology Development and Transfer project. ... INIBAP, Montpellier, France.

  7. Nuclear power plants in Germany. Recent developments in off-site nuclear emergency preparedness and response; Kernkraftwerke in Deutschland. Neue Entwicklungen im anlagenexternen Notfallschutz

    Gering, Florian [Bundesamt fuer Strahlenschutz, Oberschleissheim/Neuherberg (Germany). Abt. SW 2.2 Entscheidungshilfesysteme, Lageermittlung und Kommunikation

    2014-10-15

    The reactor accident in Fukushima, Japan, in 2011 triggered a thorough review of the off-site emergency preparedness and response for nuclear power plants in Germany. ''Off-site emergency preparedness and response'' includes all actions to protect the public outside the fence of a nuclear power plant. This review resulted in several changes in off-site emergency preparedness and response, which are briefly described in this article. Additionally, several recent activities are described which may influence emergency preparedness and response in the future.

  8. New multi-purpose lifting devices for the Grafenrheinfeld and Unterweser nuclear power plants; Neue Kombihebetraversen fuer die Kernkraftwerke Grafenrheinfeld und Unterweser

    Aiglsdorfer, Christoph [Siempelkamp Nukleartechnik GmbH, Linz (Austria)

    2011-03-15

    After the extremely successful use of the multi-purpose lifting device and the reactor pressure vessel sealing head for the Brokdorf nuclear power plant, supplied by Siempelkamp Nukleartechnik in 2008 and 2009, a further contract was received in early 2010. E.ON Kernkraft decided to also order a multi-purpose lifting device each for the power plants at Grafenrheinfeld and Unterweser from Siempelkamp. The important innovation of the Siempelkamp multi-purpose lifting device is that it is manufactured entirely from austenitic steel. This allows it to remain in its storage location on the retracted upper core grid (UCG) in the flooded reactor pool during the unloading of the fuel elements, while the fuel elements are being changed. The advantage here for the operator is that the fuel elements change is shortened even further, and this reduces costs. Saving time is also an important requirement for the RPV sealing head. For the Brokdorf nuclear power plant, Siempelkamp manufactured and supplied the RPV sealing head. A precondition of this order was a total realisation time of seven months and to save valuable time during the outage for the operating company. With a new sealing concept, a further innovation from Siempelkamp came to bear on this contract. It makes it possible to safely handle the RPV sealing head using the multi-purpose lifting device. (orig.)

  9. Implementation of a radiological emergency monitoring system for Bruce Power nuclear power plant (Canada); Implementierung eines radiologischen Umgebungsueberwachungsmesssystems fuer das Kernkraftwerk Bruce Power (Kanada)

    Madaric, M. [Saphymo GmbH, Frankfurt (Germany)

    2016-07-01

    The Bruce Power nuclear power plant (BP NPP) in Ontario, Canada, is the largest nuclear generating station in the world, operating 8 nuclear reactors producing 6300 MW. In correlation with Bruce Power's safety culture, ''Safety first'' and continuous improvements are essential and substantial parts of the Bruce Power philosophy and management system. After the Fukushima nuclear accident the existing radiological emergency monitoring was analyzed and improved.

  10. Consequences of changed nuclear power plant lifetimes in Germany. Scenario analyses until 2035; Auswirkungen veraenderter Laufzeiten fuer Kernkraftwerke in Deutschland. Szenarioanalysen bis zum Jahre 2035

    Blesl, Markus; Bruchof, David; Fahl, Ulrich; Kober, Tom; Kuder, Ralf; Beestermoeller, Robert; Goetz, Birgit; Voss, Alfred

    2011-06-01

    The report is aimed to discuss the implications of changed NPP lifetimes in Germany on energy policy, environment, energy cost and macroeconomics. An extensive scenario analysis is used considering the effects on the German energy system in the frame of the European context. It is shown that a nuclear phase-out until 2017 is technically feasible, but needs adequate replacement options that will change the German energy system in the medium term. The study shows that the time of nuclear phase-out has no significant influence on the use of renewable energies.

  11. Aspects of reactor dismantling planning following the safe entombment in the NPP Lingen (KWL); Aspekte der Abbauplanung nach dem Sicheren Einschluss im Kernkraftwerk Lingen (KWL)

    Priesmeyer, U.; Rojahn, T.; Fries, B. [Kernkraftwerk Lingen GmbH (Germany)

    2009-07-01

    The NPP Lingen (KWL) was shut-down in 1977. Due to the fact that no final repository was available the safe entombment for 25 years was chosen following the decommissioning. The conventional plant components were dismantled and removed from the plant site. The licensing procedure for reactor dismantling with final disposal in Schacht Konrad has been started. The beginning of dismantling operation is scheduled for 2013. The authors describe the preparatory work, the boundary conditions for the dismantling, radiation protection considerations with respect to manual demolition work after the rather long decay time.

  12. Ultrasonic findings in the NPP Beznau. Report on the planned further procedure of the licensee; Ultraschallbefunde des Kernkraftwerks Beznau. Stellungnahme zum geplanten weiteren Vorgehen des Betreibers

    Mohr, Simone; Pistner, Christoph

    2016-03-15

    Due to the ultrasonic findings in the reactor pressure vessel of NPP Beznau-1 in 2015 the licensee had to provide a new structural integrity analysis based on the changed material properties. The authors discuss the interpretation of the findings in Beznau with in relation to similar findings in the Belgian NPPS Doel-3 and Tihange-2. A doubtless metallurgical characterization of the irregularities in the RPV wall as not possible based on ultrasonic testing only. Destructive testing of samples from the reactor pressure vessel is also not possible since no original material bearing irregularities is available.

  13. Methods and data of probabilistic safety analysis for nuclear power plants. Status May 2015; Methoden und Daten zur probabilistischen Sicherheitsanalyse fuer Kernkraftwerke. Stand: Mai 2015

    NONE

    2016-09-15

    The supplement for the methodology of probabilistic safety analyses includes modifications, extensions and actualizations based on recent experiences. The chapter on personnel actions has been reorganized and adapted to the status of science and technology. Especially the possibility of decision fault identification and evaluation has been included. The chapters on floods and earthquakes are revised with respect to the actual regulatory developments and the new safety requirements. An extension of the spectra of PSA methods and data for the non-power operation has not been revised with respect to the Fukushima experiences. Based on fire experiences during power operation a new section on fire during non-power operation was included.

  14. Replacement of the feedwater pipe system in reactor building outside containment at the nuclear power plant Philippsburg; Austausch der Speisewasserleitung im Reaktorgebaeude ausserhalb SHB im Kernkraftwerk Philippsburg I

    Kessler, A. [Energie-Versorgung Schwaben AG, Stuttgart (Germany); Labes, M. [Siemens AG Unternehmensbereich KWU, Offenbach am Main (Germany); Schwenk, B. [Kernkraftwerk Philippsburg GmbH (Germany)

    1998-11-01

    After full replacement of the feedwater pipe system during the inspection period in 1997, combined with a modern materials, manufacturing and analysis concept, the entire pipe system of the water/steam cycle in the reactor building of KKP 1 now consists of high-toughness materials. The safety level of the entire plant has been increased by leaving aside postulation of F2 breaks in the reactor building and providing for protection against 0.1 leaks. Based on fluid-dynamic calculations for the cases of pump failure and pipe break, as well as pipe system calculations in 5 extensive calculation cycles, about 130 documents were filed for inspection and approval (excluding preliminary test documents on restraints). Points of main interest for safety analysis in this context were the optimised closing performance of the 3rd check valves and the integrity of the nozzle region at the RPV. (oirg./CB) [Deutsch] Durch den Restaustausch der Speisewasserleitungen in der Revision 1997, verbunden mit einem modernen Werkstoff-, Fertigungs- und Nachweiskonzept, sind im Reaktorgebaeude von KKP 1 in den Hauptleitungen des Wasser-Dampf-Kreislaufes nur noch hochzaehe Werkstoffe eingesetzt. Durch den Verzicht auf das Postulat von 2F-Bruechen im Reaktorgebaeude und durch die Auslegung gegen 0,1F-Lecks wird das Sicherheitsniveau der Anlage insgesamt gesteigert. Ausgehend von fluiddynamischen Berechnungen fuer Pumpenausfall und Rohrbruch sowie Rohrsystem-Berechnungen in 5 umfangreichen Berechnungskreisen wurden fuer die Genehmigung und Begutachtung ca. 130 Unterlagen (ohne Halterungs-Vorpruefunterlagen) eingereicht und vom Gutachter geprueft. Schwerpunkte der Nachweisfuehrung waren die Optimierung des Schliessverhaltens der 3. Rueckschlagarmaturen sowie der Integritaetsnachweis des RDB-Anschlusses. (orig./MM)

  15. Successful implementation of ageing management exemplified at the cooling tower of the Emsland nuclear power plant; Erfolgreiche Umsetzung von Alterungsmanagement am Beispiel Kuehlturm des Kernkraftwerks Emsland

    Fischer, Alexander [Hochtief Solutions AG, Consult IKS Energy, Frankfurt am Main (Germany). Design Kraftwerke; Dueweling, Carsten [Kernkraftwerke Lippe-Ems GmbH, Lingen (Germany). Abschnitt Bautechnik

    2013-09-01

    The paper describes the successful implementation of the restoration of water distribution channels at the cooling tower of the Emsland nuclear power plant under the aspect of ageing management. The main challenge of ageing management is the determination of potential ageing mechanism and to avoid systematically and effectively their damaging influences. In the course of the annual site inspections, abnormalities at the lower side of the water-distribution channels of the cooling tower were detected, analysed, and repaired. The procedures conserve the load bearing reinforcement only for a certain period. Therefore permanent structural monitoring is needed. (orig.)

  16. Successful implementation of ageing management exemplified at the cooling tower of Emsland nuclear power plant; Erfolgreiche Umsetzung von Alterungsmanagement am Beispiel Kuehlturm des Kernkraftwerkes Emsland

    Fischer, Alexander [Hochtief Solutions AG, Consult IKS Energy, Frankfurt am Main (Germany). Design Kraftwerke; Dueweling, Carsten [Kernkraftwerke Lippe-Ems GmbH, Lingen (Germany). Abschnitt Bautechnik

    2013-07-15

    The present paper describes the successful implementation of the restoration of water-distribution channels at the cooling tower of the Emsland nuclear power plant under the aspect of ageing management. The main challenge of aging management is the determination of potential aging mechanism and to avoid systematically and effectively their damaging influences. In the course of the annual site inspections abnormalities at the lower side of the water-distribution channels of the cooling tower were detected, analysed, and repaired. The extraordinary high chlorine equivalent of the cooling water was identified as main reason of the damages located. Due to extensive infiltration into the concrete structure, chloride-induced corrosion generates a volume expansion of the reinforcement and thereby to a blast off of the concrete covering. According to the restoration concept, the damaged concrete was removed by maximum pressure water jet blasting; where necessary the reinforcement was retrofitted and a layered concrete substitution was applied by synthetic cement mortar. The realised procedures conserve the load bearing reinforcement only for a certain period, because the permanent chloride infiltration could not be stopped. Therefore, the structure has to be monitored permanently. (orig.)

  17. Replacement of the cooling tower packing at the Goesgen-Daeniken AG nuclear power plant; Ersatz der Kuehlturmeinbauten im Kernkraftwerk Goesgen-Daeniken

    Rich, Hans Walter [Kernkraftwerk Goesgen-Daeniken AG, Daeniken (Switzerland)

    2012-07-01

    In 2005 the asbestos cement cooling tower packing was replaced by plastic material. Two years later, the packing showed strong deformations, deposits of solids and weight gain. At the end of 2007 parts of the packing collapsed into the cooling tower basin. Investigations were made, revealing that the thickness of the packing foil was too low and that packing geometry and biofilms on the surface of the packing favoured deposition of solids. Successful measures were taken to solve the problems. (orig.)

  18. Periodical safety review of the Goesgen-Daeniken nuclear power plant. Summary, results and evaluation; Periodische Sicherheitsueberpruefung fuer das Kernkraftwerk Goesgen-Daeniken. Zusammenfassung, Ergebnisse und Bewertung

    NONE

    1999-11-15

    The Goesgen nuclear power plant (KKG) received its operational licence on September 9, 1978. The operational start-up of the plant went on into the year 1979, but there was a short interruption because of the accident in the Three Mile Island reactor on March 28, 1979. In May 1985 KKG submitted a request for raising the thermal reactor power from the then 2808 MW to 3002 MW. Based on the examination by the Federal Agency for the Safety of Nuclear Installations (HSK), the Swiss Federal Council granted the licence in two steps: in December 1985 for raising the thermal power to 2900 MW, and, in April 1992, to 3002 MW. The licence for the second step was given under the condition that some more experience was to be gained concerning the fuel rod cladding under higher loading. As part of the yearly re-licensing on restart after fuel assembly reloading, HSK confirmed that the plant status conformed to the legal requirements. In November 1986, HSK asked all Swiss nuclear power plant managers to state their opinions on proposed measures concerning severe accidents. Some of the measures were already in discussion; the Chernobyl accident on April 26, 1986, accelerated their implementation and was also a reason for the introduction of the measures against severe accidents. In this context, KKG carried out a risk study which led to the installation of a filtered pressure release system for the containment. Another consequence of the Chernobyl accident was the introduction of technical Periodical Safety Reviews (PSR) for all operating nuclear power plants. Central points of the PSR are: a) comparison with the continuously improving state-of-the-art of science and technology concerning safety precautions; b) a systematic evaluation of operating experience and plant status; c) the taking into account of probabilistic safety analyses in the overall evaluation of the plant. Within the framework of the examination of the overall plant, HSK also checks how its requirements concerning plant safety and radiation protection are taken into account. Even if the plant manager considers the guarantee of plant safety as his duty, an overall investigation by the authorities makes sense because it also looks into rare accident scenarios for which there are, of course, no actual working experience and which can only be considered within the framework of extended plant examinations. The PSRs on the Swiss nuclear power plants therefore complement the continuous control activities of the HSK; they are carried out about every 10 years. For KKG the PSR process was initiated by a letter from the HSK in February 1994. The areas to be considered were: a) examination of design and fulfilment of technical safety systems and comparison with the actual state-of-the-art of science and technology; b) evaluation of operational experience; c) review of the technical precautions against severe accidents including the preparation of emergency measures; d) review of the emergency organisation; e) examination of the plant protection against radioactivity; f) future dismantling at the end of operational life and disposal of the radioactive wastes; g) evaluation of accident analyses and of the KKG probabilistic safety analysis; h) review of plant organisation and plant management. The examination confirmed that, at KKG, there are very many technical safety precautions. KKG operational experience is good, the results show a high degree of operational availability and a very low number of incidental shut-downs. In international comparison the collective doses of the staff are low and the release of radioactive materials to the environment is negligible; on this account KKG is one of the world's best plants operating pressurised water reactors. Up to now the examinations have not brought any ageing deterioration to light concerning the status of safety-relevant components or ducts

  19. Hypofractionated stereotactic body radiotherapy (SBRT) for liver metastases. A retrospective analysis of 74 patients treated in the Klinikum rechts der Isar Munich

    Heppt, Franz Johannes

    2013-01-01

    Purpose of this study was to evaluate the outcome of stereotactic body radiotherapy (SBRT) of liver metastases and prognostic factors for local control and overall survival. From 2000 to 2009 74 patients with 91 metastases were treated at the Department for Radiation Therapy and Oncology (TU Muenchen). With an observed local control rate of 75% after 1 year, SBRT proved as an effective local treatment option. Unfortunately, systemic tumor progression still dominates long term survival in many patients.

  20. Randomized Comparison of Paclitaxel-Eluting Balloon and Stenting Versus Plain Balloon Plus Stenting Versus Directional Atherectomy for Femoral Artery Disease (ISAR-STATH).

    Ott, Ilka; Cassese, Salvatore; Groha, Philipp; Steppich, Birgit; Hadamitzky, Martin; Ibrahim, Tareq; Kufner, Sebastian; Dewitz, Karl; Hiendlmayer, Regina; Laugwitz, Karl-Ludwig; Schunkert, Heribert; Kastrati, Adnan; Fusaro, Massimiliano

    2017-06-06

    Atherosclerosis in the superficial femoral artery is common in patients suffering from peripheral artery disease. Paclitaxel-eluting balloon (PEB) angioplasty, stenting, and directional atherectomy (DA) have provided new options for the treatment of superficial femoral artery disease; however, the comparative efficacy of these interventional strategies remains uncertain. One hundred and fifty-five patients with symptomatic peripheral artery disease due to de novo superficial femoral artery stenotic or occlusive lesions were randomized to treatment with plain balloon angioplasty (BA) followed by PEB angioplasty and stenting (n=48), BA and stenting (n=52), or DA with distal protection and bailout stenting (n=55). The primary end point of the study was percentage diameter stenosis after 6 months measured by angiography. Other end points included target lesion revascularization, thrombosis, ipsilateral amputation, binary restenosis, and all-cause mortality at 6 and 24 months. Baseline and lesion characteristics were comparable in all groups with a mean lesion length of 65.9±46.8 mm and 56% total occlusions. At 6 months angiography, the percent diameter stenosis was significantly lower in patients treated by PEB angioplasty and stenting (34±31%) as compared with BA angioplasty and stenting (56±29%, P =0.009) or DA (55±29%, P =0.007). Similarly, binary restenosis was significantly lower after treatment with PEB and stenting as compared with BA and stenting or DA. Clinical follow-up at 24 months revealed a lower risk for target lesion revascularization after PEB angioplasty and stenting as compared with BA and stenting or DA. We found no difference in terms of target lesion thrombosis and mortality among groups, and no patient underwent amputation. Treatment of de novo superficial femoral artery lesions with PEB angioplasty and stenting is superior to BA angioplasty and stenting or DA in terms of angiographic diameter stenosis at 6 months and target lesion revascularization at 24 months. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00986752. © 2017 American Heart Association, Inc.

  1. Occupational safety in the nuclear power plant. The contribution of sociology to the development of a communication tool for the elimination of hazardous situations; Arbeitssicherheit im Kernkraftwerk. Der Beitrag der Sozialpsychologie zur Entwicklung eines Kommunikationsinstrumentes fuer die Behebung von Gefaehrdungssituationen

    Zedler, Christien [IAOP - Institut fuer Arbeitspsychologie, Organisation und Prozessgestaltung, Berlin (Germany); Huber, Veit [E.ON Kernkraft GmbH (Germany)

    2012-11-01

    Nuclear power plant companies make efforts to enhance the operational safety in the plant. Despite a variety of measures the number of accidents at work is still too high, esp. for external personnel. Social psychological considerations were used to develop communication tools for the elimination of hazardous situations, for instance by safety dialogues between employees. The observation of hazardous situations should trigger communication and discussion on the risk of the specific situation. In the contribution practical experiences and recommendations for the realization of a safety dialogue culture in the NPP Grafenrheinfeld are summarized and illustrated by examples.

  2. Project 'WINDBANK mittleres Aaretal' - Analysis, Diagnosis and Forecast of Wind Fields around the Nuclear Power Plant Goesgen; Projekt 'WINDBANK mittleres Aaretal' - Analyse, Diagnose und Prognose der Windverhaeltnisse um das Kernkraftwerk Goesgen

    Graber, W.K.; Tinguely, M

    2002-07-01

    An emergency decision support system for accidental releases of radioactivity into the atmosphere providing regional wind field information is presented. This system is based on intensive meteorological field campaigns each lasting 3-4 months in the regions around the Swiss nuclear power plants. The wind data from temporary and permanent stations are analysed to evaluate the typical wind field patterns occurring in these regions. A cluster analysis for these data-sets lead to 12 different wind field classes with a high separation quality. In the present report, it is demonstrated that an on-line acquisition of meteorological data from existing permanent stations is enough to diagnose the recent wind field class in a region with a radius of 25 km around the nuclear power station of Goesgen with a probability of 95% to hit the correct class. Furthermore, a method is presented to use a high resolution weather prediction model to forecast the future wind field classes. An average probability of 76% to hit the correct class for a forecast time of 24 hours is evaluated. Finally, a method for parameterization of turbulence providing input for dispersion models from standard meteorological online data is presented. (author)

  3. Safety technical considerations on the 2012 periodic safety verification of the Beznau nuclear power plant; Sicherheitstechnische Stellungnahme zur Periodischen Sicherheitsüberprüfung 2012 des Kernkraftwerks Beznau

    NONE

    2016-12-15

    According to nuclear legislation, the owner of an operational license for a nuclear power plant has to provide a periodic safety verification (PSU) every 10 years. The 'North Eastern Power Plants' company (NOK), today AXPO Power AG already performed such a PSU for the Beznau-2 nuclear reactor block (KKB2) in 2002. The Beznau-1 nuclear reactor block (KKB1) received its definitive operational license in October 1970, after test operation during 7 months. After the license for test operation received on July 16{sup th}, 1971, the operational license of KKB2 was renewed several times, each time for a certain period of validity. In 1991, NOK requested a definitive operational license for KKB2, but in 1994 the Swiss Federal Council lengthened the license for only 10 years. Moreover, it laid down that NOK has to periodically report on the safety of the facility. With its letter of August 23{sup rd}, 1998, the Federal Office of Energy defined the documents to be produced for the PSU. The extent of the PSU was defined in such a way that many documents concern the whole power plant, i.e. both nuclear reactor blocks. On December 3{sup rd}, 2004, the Swiss Federal Council granted KKB2 an operational license of limited validity. The present report reviews the 2012 PSU, which covers the time interval from January 1{sup st}, 2002, to December 31{sup st}, 2011, from the point of view of safety. It contains documents for the evaluation of both reactor blocks at KKB. The Beznau interim storage pool was also taken into consideration; it is situated on the KKB site, but, according to a decision of the Swiss Federal Council of May 23{sup rd}, 1991, it has an independent operational license. The evaluation of ageing surveillance takes the whole operational period of the facility into account, i.e. the ageing mechanisms acting as from the beginning of the operation. Moreover, important developments that occurred after the surveillance time interval have been taken into account, especially the status of the examination of the defects discovered during the revision shutdown in 2015 concerning the material of the reactor pressure vessel of block 1. As far as the NOK’s request for an unlimited operational license is concerned, NOK has to prove in time, before the 40-year license limit is up, that the design boundaries of safety-relevant components will not be reached during the duration of extended operation. Otherwise, the necessary refit works have to be performed in time. KKB has produced the requested proof for the long-term operation of both blocks. The results of the supervisory work carried out by the Swiss Federal Nuclear Safety Inspectorate (ENSI) were published in the safety technical review for KKB1 and KKB2. ENSI concludes that there are no safety technical objections against the operation of both blocks beyond the limit of 40 years. On the basis of the state of knowledge when the considerations were made, the criteria for shutting down will not be reached in the 10 following operational years, neither by KKB1 nor by KKB2.

  4. Recurrent safety inspection of German nuclear power plant - performance, schedule and goals. As of 11 August 1995; Periodische Sicherheitsueberpruefung (PSUe) fuer deutsche Kernkraftwerke - Durchfuehrung der PSUe. Vom 11. August 1995

    NONE

    1995-08-23

    The recurrent safety inspection is intended as an inspection supplementing the continuous operation monitoring activities within the framework given by the supervisory activities of the supervisory authority. The first recurrent safety inspection is scheduled to be performed about ten years after start-up of the plant, with subsequent inspection intervals to cover ten-year periods, and recorded operating and monitoring results to be taken into account at each recurrent inspection. The purpose of the recurrent safety inspections is to ascertain that post-inspection operation of the plant meets the then required safety standards. Significant testing results of the latest inspection are to be analysed and compared with regard to the current state of the art and operating results accumulated since the previous inspection, for subsequent definition of enhancements if required. (orig./HP) [Deutsch] Die PSUesoll eine Ergaenzung der staendigen Ueberpruefung im Rahmen der atomrechtlichen Aufsicht ueber den Betrieb sein. Eine erstmalige PSUesoll etwa zehn Jahre nach Inbetriebnahme erfolgen. Die weiteren Ueberpruefungen sollen danach jeweils im Abstand von etwa zehn Jahren stattfinden. Die zwischenzeitlichen Erfahrungen aus Betrieb und Aufsicht sind einzubeziehen. Ziel der PSUemuss sein, festzustellen, ob die Anlage auch im Hinblick auf den kuenftigen Betrieb ein ausreichendes Sicherheitsniveau besitzt. Zu diesem Zweck muessen repraesentative Ereignisse dann detailliert untersucht werden, wenn neue Erkenntnisse aus Forschung und Entwicklung sowie aus der Betriebserfahrung seit der letzten Periodischen Sicherheitsueberpruefung dies erfordern. (orig./HP)

  5. Target: The green meadow. How much knowledge is needed for the dismantling of nuclear power plants?; Ziel: die Gruene Wiese. Wieviel Know-how man braucht, um ein Kernkraftwerk zurueckzubauen

    Bach, Friedrich-Wilhelm; Hassel, Thomas [Unterwassertechnikum Hannover (UWTH), Hannover (Germany). Inst. fuer Werkstoffkunde

    2013-07-01

    As from the year 2022, there will no nuclear power plant exist in Germany. In the contribution under consideration two scientists from the Institute of Materials Science (Hanover, Federal Republic of Germany) report on the preparations and the necessary technical knowledge in order to dismantle the highly complex nuclear facilities and to recultivate former nuclear power plant sites.

  6. Transfer of financial obligations for the disposal of nuclear waste and decommissioning of German NPP's. Legal aspects of a trust model; Sicherstellung der finanziellen Entsorgungsvorsorge fuer die Stilllegungs- und Rueckbaukosten der deutschen Kernkraftwerke. Rechtliche Randbedingungen eines Stiftungsmodells

    Schewe, Markus; Wiesendahl, Stefan [Kuemmerlein Rechtsanwaelte und Notare, Essen (Germany)

    2015-04-15

    The nuclear power plant operators have to bear the costs associated with the closure and the decommissioning of the German nuclear power plants as well as the costs for the disposal of nuclear waste. For that purpose, the operators have to build up sufficient reserves for the decommissioning phase. These reserves at the end of 2013 amounted to approximately 36 billion Euro. Changing this system is discussed very so often. Last in May 2014, a public debate started dealing with the so called trust model (''Stiftungsmodell''). The press published deliberations of several operators to transfer their entire nuclear business to the Federal Republic of Germany. Under this deliberation the current nuclear power plant operations, as well as closure obligations would be contributed to trust. Further, also the reserves should be ''transferred'' to the trust. RAG-Foundation (RAG-Stiftung) - which will assume the financial obligations in connection with Germany's closure of underground coal mining activities - sometimes is cited as a role model. The article covers elements of German trust law and atomic energy law regarding such deliberations. In trust law e.g. it can be debated whether the trust should be established under public or - as in the case of RAG-Foundation - under private law. In this context we will set out the major differences between those two options. In the public law part we will notably address issues arising from individual licensing requirements for nuclear power plants and focus on questions concerning reliability, requisite qualification and organizational structures.

  7. Expertise about the request of the nuclear power plant Leibstadt for increasing the power to 3600 MW{sub th}; Gutachten zum Gesuch des Kernkraftwerks Leibstadt um Leistungserhoehung auf 3600 MW{sub th}

    NONE

    1996-03-15

    On July 31, 1992, the nuclear power plant Leibstadt AG (KKL) submitted a request for a modification of its operation license for increasing the reactor thermal power to 3600 MW. In its examination, the Federal Agency for the Safety of Nuclear Installations (HSK) investigated the effects of the power increase on reactor safety, especially on the safety criteria which can limit the power. In doing this, a distinction has to be made between normal operation, design incidents and out-of-design accidents. KKL is a boiling water reactor (BWR) with a current maximum thermal power of 3,138 MW with 648 fuel assemblies in the core. Since the start of operation in February 1984, the reactor has been continuously improved and now almost fulfils the present state-of-the-art of science and technology for BWRs. After some incidents during the early years, the plant shows a high level of availability. During the past 6 years some fuel assembly damage has cast a shadow on good operational experience, but until now the collective irradiation dose of the plant staff and the environment has remained mostly below legal limits, as well as for the release of radioactive materials to the atmosphere and to the Rhine River. Calculations of core loading with the fuel assemblies presently used at KKL have shown that the operation and safety limits of the reactor core can still be preserved with a thermal power of 3600 MW. For normal operation, no objection can be raised against the power increase. This increase, however, has to be carried out step-by-step in order to gain experience concerning plant behaviour. With the higher power rating, increased dose rates are expected on systems and components, in plant rooms and in the plant area, which also leads to increased dose rates to the staff and environment. This increase has to be estimated and, possibly, correction measures will have to be taken in order to reduce them. Especially to be monitored is the dose rate increase in the machine hall. In the case of design incidents too, all safety-relevant limits and the maximal tolerable dose rates in the environment must be respected. In the context of design incidents, the 'transitory' group also constitutes the limiting case with the higher power. For the complete judgement of the safety of a nuclear power plant it is not sufficient to estimate the effects of a design incident through deterministic methods. The evaluation of the effects of out-of-design accidents needs a probabilistic safety analysis which determines the frequency as well as the consequences of an accident. The results show that KKL represents a very small risk for the environment. In KKL the measures necessary for safe operation and protection of mankind and environment at a thermal power of 3600 MW have already been taken or will be taken shortly. According to its examination, HSK concludes that there are no safety-relevant reasons speaking against an operational license for the increased thermal power. The increase will, however, have to be carried out in 4 steps of 1 year each in order to gain operational experience

  8. How does react power price on a possible lifetime extension for power plants? Nuclear power, power prices and power market models; Wie reagiert der Strompreis auf eine moegliche Verlaengerung der Laufzeiten fuer Kernkraftwerke? Kernkraft, Strompreis und Strommarktmodelle

    Nestle, Uwe [Buendnis 90/Die Gruenen, Berlin (Germany). Bundesarbeitsgemeinschaft Energie

    2010-08-23

    Extending the life of the nuclear power plants currently operated in Germany is being discussed in the light of a more likely change in government for a Christian Democrat/Liberal coalition. The reason cited most frequently is the impossibility to meet the objectives of climate protection without raising further the price of electricity if the life of nuclear power plants cannot be extended. The question to be looked into is that of the legal pre-requisites to be established in Germany in order for the existing nuclear power plants to be operated for longer periods of time. So in this contribution some discussion is done wether a possible lifetime extension of nuclear power plants will react on power prices.(GL)

  9. Catalogue of requirements for a plant-specific safety inspection of German nuclear power plants taking into account the Fukushima-I (Japan) events; Anforderungskatalog fuer anlagenbezogene Ueberpruefungen deutscher Kernkraftwerke unter Beruecksichtigung der Ereignisse in Fukushima-I (Japan)

    NONE

    2011-03-30

    The catalogue of requirements for a plant-specific safety inspection of German nuclear power plants taking into account the Fukushima-I (Japan) events worked out by the German RSK (reactor safety commission) includes the following inspection topics: natural events like earth quakes, floods, weather-based consequences and possible superposition; civilization-based events like airplane crash, gas release, reactor accident consequences for neighboring units, terroristic impacts, external attacks on computer-based control systems. Further event-independent assumptions have to be considered: station blackout, long-term emergency power supply requirement, failure of auxiliary cooling water supply, efficacy of preventive measures, aggravating boundary conditions for the performance of emergency measures.

  10. The German-German history of the nuclear power plant Greifswald. Nuclear power between east and west. 2. ed.; Die deutsch-deutsche Geschichte des Kernkraftwerkes Greifswald. Atomenergie zwischen Ost und West

    Hoegselius, Per [Technische Hochschule Stockholm (Sweden). Bereich Gesellschaft, Wissenschaft und Technik

    2015-07-01

    The historical study covers the chapters The nuclear power plant Greifswald; Lubmin shortly before the ''Wende'' 1989; the German ''Wende''; from the last vote for the ''Volkskammer (parliament of the German Democratic Republic) to the German reunification; Lubmin in reunified Germany; conclusions and perspectives. In the attachment technical data about the reactors WWER-440/W-230 are summarized, including a list of WWERs in the former eastern bloc countries.

  11. Comparison of the Absorbable Polymer Sirolimus-Eluting Stent (MiStent) to the Durable Polymer Everolimus-Eluting Stent (Xience) (from the DESSOLVE I/II and ISAR-TEST-4 Studies).

    Lansky, Alexandra J; Kastrati, Adnan; Edelman, Elazer R; Parise, Helen; Ng, Vivian G; Ormiston, John; Wijns, William; Byrne, Robert A

    2016-02-15

    We compared the outcomes of a novel, thin-strut, cobalt-chromium, absorbable, polymer sirolimus-eluting stent (APSES; MiStent) to the durable polymer cobalt-chromium everolimus-eluting stent (EES; Xience). A propensity-matched analysis was performed comparing data from the DES With Sirolimus and a Bioabsorbable Polymer for the Treatment of Patients With De Novo Lesions in the Native Coronary Arteries (DESSOLVE) I and II studies, evaluating the APSES to the EES arm of the Intracoronary Stenting and Angiographic Results: Test Efficacy of 3 Limus-Eluting Stents-4 study. Target lesion failure (TLF) and its components were evaluated at 12 months and annually to 3 years; 805 patients (APSES = 153; EES = 652) were included with propensity matching in 204 patients (APSES = 102; EES = 102). APSES compared with EES had lower TLF at 1 year (3.0% vs 8.0%, p = 0.12) driven by a difference in target lesion revascularization (TLR; 1% vs 6%, p = 0.05), with no difference in target vessel myocardial infarction (p = 0.56) or stent thrombosis (p = 0.31). At 3 years, TLF (5.0% vs 12.5%, p = 0.07) and TLR (2.0% vs 8.4%, p = 0.04) remained lower with APSES. By landmark analysis, there was no significant difference in TLF between 1 and 3 years (p = 0.36). In conclusion, in a propensity-matched analysis, the APSES demonstrated reduced clinically indicated TLR rates at 1 and 3 years compared with the durable polymer EES, with minimal accrual of events between 1 and 3 years. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Inverse synthetic aperture radar imaging principles, algorithms and applications

    Chen , Victor C

    2014-01-01

    Inverse Synthetic Aperture Radar Imaging: Principles, Algorithms and Applications is based on the latest research on ISAR imaging of moving targets and non-cooperative target recognition (NCTR). With a focus on the advances and applications, this book will provide readers with a working knowledge on various algorithms of ISAR imaging of targets and implementation with MATLAB. These MATLAB algorithms will prove useful in order to visualize and manipulate some simulated ISAR images.

  13. Joint inference of dominant scatterer locations and motion parameters of an extended target in high range-resolution radar

    De Freitas, A

    2015-06-01

    Full Text Available of scatterers using the PF method are compared with those obtained using standard range-Doppler inverse synthetic aperture radar (ISAR) imaging when using the same radar returns for both cases. The PF infers the location of scatterers more accurately than ISAR...

  14. Grohnde. Documentation of the police operation during the demonstration against the NPP Grohnde on 19.03.1977 and the evacuation of the occupied cooling tower site on 23.08.1977; Grohnde. Dokumentation der Polizeieinsaetze anlaesslich der Demonstration gegen das Kernkraftwerk Grohnde am 19.03.1977 und der Raeumung des besetzten Kuehlturmgelaendes am 23.08.1977

    Stricker, Michael

    2014-07-01

    The documentation of the police operation during the demonstration against the NPP Grohnde on 16.03.1977 and the evacuation of the occupied cooling tower site on 23.08.1977 covers the following issues: involved action forces: police Niedersachsen, police Nordrhein-Westfalen, police Schleswig-Holstein, police Bremen and the Bundesgrenzschutz; concept of the police operation, provisions (lodging and board) for the police, operating resources, details of the operation sequence; post-processing of the operation; the Grohnde trials.

  15. CASTOR {sup registered} 1000/19. Transport and storage cask for the disposal of spent fuel from the nuclear power plant Temelin (Czech Republic); CASTOR {sup registered} 1000/19. Transport- und Lagerbehaelter zur Entsorgung abgebrannter Brennelemente aus dem Kernkraftwerk Temelin in Tschechien

    Fopp, Stefan; Kuehne, Bernhard; Schroeder, Jens [GNS Gesellschaft fuer Nuklear-Service mbH, Essen (Germany)

    2011-07-01

    The transport and storage cask CASTOR {sup registered} 1000/19 was designed for a dry interim storage of 19 spent fuel elements of WWER-1000 reactors. The project performed by GNS mbH included design, manufacture, licensing and delivery of 36 casks. The specific requirements for NPP Temelin concern loading and dispatch of the casks to be performed during the outage period of the reactor, thus high reliability and functionality of the casks and the manipulation equipment. The paper describes the mechanical design of the cask, stress analyses for a hypothetical fall accident from 9 m height, performed using the FEM program ANSYS and LS-DYNA. The 3D simulation models are based on conservative material characteristics and upper-bound boundary conditions. The safety analysis was performed using qualified software programs validated by the Czech authorities.

  16. Studies on the 'air-grass-cow-milk' exposure pathway of airborne /sup 131/I from Wuergassen nuclear power plant in the 1980 grazing season. Untersuchungen zum Expositionspfad 'Luft-Gas-Kuh-Milch' fuer Jod 131 in der Abluft des Kernkraftwerkes Wuergassen waehrend der Weidezeit 1980

    Haubelt, R; Burkhardt, J

    1983-12-01

    The measurements and statistics, which were much more detailed than the annual routine measurements, included /sup 131/I emission measurements on the stack, the registration of meteorological parameters, measurements of /sup 131/I concentrations in air, grass, and milk, and supplementary statistics on the farmers' animal keeping habits. The infant thyroid dose resulting from /sup 131/I in milk was found to be lower by at least one order of magnitude than the value calculated from the emission data for the point of maximum exposure according to the Guideline to Explain Sect. 45 StrlSchV. This result confirms the results of earlier investigations. The model calculation according to the Guideline yields a value of 30 mrem for incorporation of /sup 131/I into the infant thyroid via the ingestion pathway for the year 1980, i.e. 25 times the measured value. The possible reasons for this are discussed.

  17. The development of engineered safeguards for nuclear power plants in the political and technical environment in the Federal Republic of Germany since 1955; Die Entwicklung der Sicherheitstechnik fuer Kernkraftwerke im politischen und technischen Umfeld der Bundesrepublik Deutschland seit dem Jahr 1955

    Laufs, P. [Stuttgart Univ. (Germany). Philosophische-Historische Fakultaet

    2007-01-15

    The safety of nuclear power plants is determined largely by the integrity of the internally pressurized coolant containment system. The highly radioactive materials (fission products) generated within this pressurized containment (primary system) in the reactor core during nuclear power plant operation constitute an extremely great potential hazard. Catastrophic failure of the primary system, and the release into the environment of the radioactive inventory, must be avoided at all costs. Because of the high coolant pressure and the high power density, pressurized water reactors (PWR) impose particularly strict requirements with respect to reactor safety. German nuclear power plants equipped with light water reactors enjoy the reputation of being among the safest plants in the world. This frequent statement is justified in the light of the research and development work performed jointly by industry, government agencies, science, and expert bodies between the 1960s and the 1990s. The research projects, which implied considerable financial expenditures, their internationally acknowledged results, and the resultant additional backfitting measures conducted in German nuclear power plants at many billions of expenditures, were hardly noticed by the German body politic. (orig.)

  18. Exercise ''contact point for persons from the neighborhood of a nuclear power station after a severe accident''; Uebung ''Kontaktstelle fuer Personen aus der Umgebung eines Kernkraftwerkes nach einem schweren Unfall''

    Stuerm, R.P. [SafPro AG, Ausbildung und Beratung in Strahlenschutz, Basel (Switzerland); Schubiger, V.; Voegtli, M. [Abt. Militaer und Bevoelkerungsschutz des Kantons Aargau (Switzerland)

    2001-07-01

    After a severe nuclear power station accident with release of radioactivity, some few persons in the neighbourhood of the station may accumulate a dose of more than 1 Sv. A lot of other people may be in doubt, whether they have received a radiation dose. Hospitals and practitioners may break down under the run on them by terrified persons, who have no or only small doses. In order to prevent this, 'assembly centers' should be run at the outer limit of the irradiated area. About 1'000 persons per day from the INNER, MIDDEL and OUTER irradiated regions should be informed and psychologically attended. A concept for such a 'assembly center' has been elaborated by members of the National Commission for AC-Protection, the Office for Protection of the Population, the National Alarm Center, the Swiss Inspectorate for the Safety of Nuclear Power Stations as well as public health officers. The concept has been tested in an exercise with 185 persons. (orig.) [German] Wenn bei einem schweren KKW-Unfall mit Austritt von Radioaktivitaet die alarmierte Bevoelkerung die angeordneten Schutzmassnahmen nicht ergreifen wuerde, koennten in der allernaechsten Umgebung des KKW einige wenige Personen Strahlendosen von mehr als 1 Sv akkumulieren und in der weiteren Umgebung viele Personen mittlere und kleine Dosen erhalten. Um eine moegliche Strahlendosis bei diesen Personen (aber auch bei solchen, die im Zweifel sind) zu ermitteln, sollen am Rande der betroffenen Region Informationsstellen mit orts- und ereignisbezogener (individueller) Personenbeurteilung sowie psychologischer Betreuung errichtet werden; denn die Einrichtungen des oeffentlichen Gesundheitswesens (Spitaeler) und die privaten Arztpraxen waeren nicht in der Lage, einen groesseren Ansturm von zu beratenden Personen zu bewaeltigen, die groesstenteils gar nicht gefaehrdet sein duerften. Diese sog. Kontakstellen sind keine generellen Dekontaminationsstellen, bieten keine generellen medizinische Dienste an und sind auch keine Auskunftszentren fuer die Medien. Rund 1'000 Personen sollen pro 24 Stunden auf einer Kontaktstelle betreut werden, wobei rund 500 Personen mit Dosen von weniger als 50 mSv (Gruppe D), rund 300 Personen mit Dosen zwischen 50 und 500 mSv (Gruppen C und B) und knapp 200 Personen mit Dosen ueber 500 mSv (Gruppe A) erwartet werden. Unter diesen 1'000 Personen duerfte es 30 schwangere Frauen (Gruppe E) haben. Mittels eines einfachen Leitsystems sollen die Ratsuchenden in die Gruppen A bis E eingeteilt werden. Diese Einteilung erfolgt durch Selbstdeklaration (Aufenthaltsort waehrend der Wolkenphase), die bei der Gruppe A durch geschultes Personal mittels Integrationsberechnungen der Ortsdosisleistung individuell verifiziert wird. Die uebrigen Besucher der Kontaktstellen werden in Gruppen durch Aerzte und Strahlenphysiker informiert und psychologisch betreut. Mitglieder der Eidgenoessischen Kommission fuer AC-Schutz, der Abteilung Militaer und Bevoelkerungsschutz, der Nationalen Alarmzentrale, der Hauptabteilung fuer die Sicherheit von Kernanlagen sowie Kantonsaerzte (Leiter des Aerztlichen Dienstes der Landesgesundheitsbehoerde) hatten ein Konzept fuer solche Kontaktstellen ausgearbeitet. Am 26.10.00 fand eine Uebung im Massstab 1:10 mit 85 Figuranten und knapp 100 Beuebten statt, um dieses Konzept auf seine Machbarkeit zu pruefen. (orig.)

  19. Comments on conceptual questions concerning the clearance of wastes for disposal on a dump site during the decommissioning and dismantling of the nuclear power plant Obrigheim (KWO); Stellungnahme zu konzeptionellen Fragen der Freigabe zur Beseitigung auf einer Deponie bei Stilllegung und Abbau des Kernkraftwerks Obrigheim (KWO)

    Kueppers, Christian

    2015-08-03

    The comments on conceptual questions concerning the clearance of wastes for disposal on a dump site during the decommissioning and dismantling of the nuclear power plant Obrigheim (KWO) cover the following issues: fundamentals of the 10 micro-Sv concept for clearance; specific regulations for the clearance of wastes from the dismantling of KWO for disposal on a dump site; disposal concept at shutdown and dismantling of KWO; measurements and control during clearance for disposal during shutdown and dismantling of KWO; documentation and reports.

  20. The 500 billion euro market. Dismantling of nuclear power plants; Der 500-Milliarden-Euro-Markt. Rueckbau von Kernkraftwerken

    Trueck, Peter [Rochus Mummert Clean Energy, Hamburg (Germany); Oberle, Berthold [Rochus Mummert Clean Energy, Hamburg (Germany). Technologieberatung und Interim Management

    2013-10-01

    The decommissioning of the shut-down nuclear power plants is an enormous market potential. In order to develop this strategic business segment, different strategies offer for companies. [German] Der Rueckbau der abgeschalteten Kernkraftwerke bildet ein enormes Marktpotential. Um dieses strategische Geschaeftsfeld zu erschliessen, bieten sich fuer Unternehmen unterschiedliche Strategien an.

  1. A phylogenetic perspective on the individual species-area relationship in temperate and tropical tree communities.

    Yang, Jie; Swenson, Nathan G; Cao, Min; Chuyong, George B; Ewango, Corneille E N; Howe, Robert; Kenfack, David; Thomas, Duncan; Wolf, Amy; Lin, Luxiang

    2013-01-01

    Ecologists have historically used species-area relationships (SARs) as a tool to understand the spatial distribution of species. Recent work has extended SARs to focus on individual-level distributions to generate individual species area relationships (ISARs). The ISAR approach quantifies whether individuals of a species tend have more or less species richness surrounding them than expected by chance. By identifying richness 'accumulators' and 'repellers', respectively, the ISAR approach has been used to infer the relative importance of abiotic and biotic interactions and neutrality. A clear limitation of the SAR and ISAR approaches is that all species are treated as evolutionarily independent and that a large amount of work has now shown that local tree neighborhoods exhibit non-random phylogenetic structure given the species richness. Here, we use nine tropical and temperate forest dynamics plots to ask: (i) do ISARs change predictably across latitude?; (ii) is the phylogenetic diversity in the neighborhood of species accumulators and repellers higher or lower than that expected given the observed species richness?; and (iii) do species accumulators, repellers distributed non-randomly on the community phylogenetic tree? The results indicate no clear trend in ISARs from the temperate zone to the tropics and that the phylogenetic diversity surrounding the individuals of species is generally only non-random on very local scales. Interestingly the distribution of species accumulators and repellers was non-random on the community phylogenies suggesting the presence of phylogenetic signal in the ISAR across latitude.

  2. Logarithmic Laplacian Prior Based Bayesian Inverse Synthetic Aperture Radar Imaging.

    Zhang, Shuanghui; Liu, Yongxiang; Li, Xiang; Bi, Guoan

    2016-04-28

    This paper presents a novel Inverse Synthetic Aperture Radar Imaging (ISAR) algorithm based on a new sparse prior, known as the logarithmic Laplacian prior. The newly proposed logarithmic Laplacian prior has a narrower main lobe with higher tail values than the Laplacian prior, which helps to achieve performance improvement on sparse representation. The logarithmic Laplacian prior is used for ISAR imaging within the Bayesian framework to achieve better focused radar image. In the proposed method of ISAR imaging, the phase errors are jointly estimated based on the minimum entropy criterion to accomplish autofocusing. The maximum a posterior (MAP) estimation and the maximum likelihood estimation (MLE) are utilized to estimate the model parameters to avoid manually tuning process. Additionally, the fast Fourier Transform (FFT) and Hadamard product are used to minimize the required computational efficiency. Experimental results based on both simulated and measured data validate that the proposed algorithm outperforms the traditional sparse ISAR imaging algorithms in terms of resolution improvement and noise suppression.

  3. Identification of hospitalized elderly patients at risk for adverse in-hospital outcomes in a university orthopedics and trauma surgery environment.

    Janine Gronewold

    Full Text Available As a consequence of demographic changes, hospitals are confronted with increasing numbers of elderly patients, who are at high risk of adverse events during hospitalization. Geriatric risk screening followed by comprehensive geriatric assessment (CGA and treatment has been requested by geriatric societies and task forces to identify patients at risk. Since empirical evidence on factors predisposing to adverse hospital events is scarce, we now prospectively evaluated implications of geriatric risk screening followed by CGA in a university hospital department of orthopedics and trauma surgery.Three hundred and eighty-one patients ≥75 years admitted to the Department of Orthopedics and Trauma Surgery of the University Hospital Essen received Identification of Seniors at Risk (ISAR Screening followed by CGA via a geriatric liaison service in case of positive screening results. Associations between ISAR, CGA, comorbid risk factors and diseases, length of hospital stay, number of nursing and physiotherapy hours, and falls during hospital stay were analyzed.Of 381 ISAR screenings, 327 (85.8% were positive, confirming a high percentage of patients at risk of adverse events. Of these, 300 CGAs revealed 82.7% abnormal results, indicating activities of daily living impairment combined with cognitive, emotional or mobility disturbances. Abnormal CGA resulted in a longer hospital stay (14.0±10.3 days in ISAR+/CGA abnormal compared with 7.6±7.0 days in ISAR+/CGA normal and 8.1±5.4 days in ISAR-, both p<0.001, increased nursing hours (3.4±1.1 hours/day in ISAR+/CGA abnormal compared with 2.5±1.0 hours/day in ISAR+/CGA normal and 2.2±0.8 hours/day in ISAR-, both p<0.001, and increased falls (7.3% in ISAR+/CGA abnormal, 0% in ISAR+/CGA normal, 1.9% in ISAR-. Physiotherapy hours were only significantly increased in ISAR+/CGA abnormal (3.0±2.7 hours compared with in ISAR+/CGA normal (1.6±1.4 hours, p<0.001 whereas the comparison with ISAR- (2.4±2

  4. Cancellation of the Kaiseraugst nuclear power plant project

    Blocher, C.; Schoenenberger, J.; Stucky, G.

    1988-01-01

    The nuclear power plant project at Kaiseraugst has been worked on for over 20 years. In 1985 the Swiss Parliament decided to license the plant. The cost of the work to date is about 1.2 x10 6 Swiss Franks. Continuation of the project is only sensible if it can be realized within a foreseeable space of time. It is probable that the discussions concerning future energy, environment and safety will continue for a long time. If this is clear that the Kaiseraugst project will not be realized during the next five to ten years for social, civic and political reasons. A continuation of the project is not justifiable. Kernkraftwerk Kaiseraugst AG must be adequately compensated. A motion has been presented to Parliament which charges the Government to negotiate with Kernkraftwerk Kaiseraugst AG for cancellation of the project

  5. Nursing Assessment and Intevention for Older People after Acute Medical Admission

    Rosted, Elizabeth Emilie

    and intervention, ISAR II, developed by McCusker et al.. ISAR II comprises a checklist of physical, mental, medical and social problems. Focus was on unresolved problems that required medical intervention, new/different community assistant services, or comprehensive geriatric assessment. After assessment the nurse...... stay. Thus, we must keep in mind that when older persons state that they are “too ill” to participate in studies, they are credible and we must listen and assist them....

  6. Scientific-technical cooperation with foreign (esp. Europe and INSC partner countries) nuclear regulatory authorities and their technical support organizations in the fields of nuclear safety of operating nuclear power plants and on the concept evaluation of generation 3+ plants. Final report; Wissenschaftlich-Technische Zusammenarbeit (WTZ) mit auslaendischen (insbesondere in Europa und INSC-Partnerstaaten) atomrechtlichen Behoerden und deren Sachverstaendigenorganisationen zur nuklearen Sicherheit in Betrieb befindlicher Kernkraftwerke und zur Konzeptbewertung von Generation-3+-Anlagen. Abschlussbericht

    Wolff, Holger

    2016-09-15

    The BMUB/BfS-Project 3614I01512 forms the frame of the GRS for the scientific-technical cooperation with Technical Support Organisations and Nuclear Regulatory Authorities in the field of nuclear safety in operating NPPs and for the concept evaluation of generation 3{sup +} plants in Europe and INSC Partner Countries. In the present final project report results are described which were gained within the project duration 15.10.2014 up to the 30.09.2016 in the following working packages: Investigations following the catastrophe of Fukushima Daiichi, Evaluation of selected National Action Plans, DBA and severe accident analyses for NPP with PWR (WWER-440, WWER-1000), cooperation with INSC partner countries on DBA, BDBA and severe accident analyses for WWER plants of generation 3{sup +} and building NRA and safety evaluation capacities and decommissioning of nuclear facilities and disposal of radioactive waste. The results are preceded by an outline on the activities related to the project management and to the planning of the bilateral work.

  7. Studies on the deterministic and probabilistic assessment of external effects. Deterministic investigation of the robustness of German nuclear power plants against external effects under consideration of actual findings on the events to be assumed; Untersuchungen zur deterministischen und probabilistischen Bewertung von Einwirkungen von aussen (EVA-Ereignisse). Deterministische Untersuchung der Widerstandsfaehigkeit deutscher Kernkraftwerke gegen Einwirkungen von aussen, unter Beruecksichtigung aktueller Erkenntnisse hinsichtlich der anzusetzenden Einwirkungen

    Sperbeck, Silvio; Strack, Christian; Thuma, Gernot

    2013-11-15

    The aim of the analyses on natural hazards described in this report was to evaluate the advantages of innovative hazard assessment methods available today over the hazard assessment methods commonly applied for German nuclear power plant sites in the past. For each hazard under consideration (earthquake, flooding, and wind loads) it has been assessed whether the new methods provide additional insights that could call for their mandatory application in future site specific hazard assessments. If no additional insights are gained, the hitherto applied methods can be considered adequate according to today's standards. In the context of this work, no areas could be identified where the hazard assessment methods stipulated in German (nuclear) regulations are generally inadequate. These methods that are commonly applied in practice do not seem to be prone to significantly underestimate the site specific hazard. Nevertheless, some newer methods allow for more precise (reduction of uncertainties) and more comprehensive (consideration of additional hazard characteristics) hazard assessments. Therefore, depending on the hazard under consideration, it could be advisable to supplement future site specific hazard assessments by some additional analyses. As the methods for some of these additional analyses are not yet fully developed, further research will be necessary to enable these amendments.

  8. Fotografie und atomare Katastrophe

    Bürkner, Daniel

    2015-01-01

    Die Dissertation setzt sich mit den fotografischen Repräsentationen der Atombombenabwürfe auf Hiroshima und Nagasaki sowie der Havarie des Kernkraftwerks Tschernobyl auseinander. Dabei werden künstlerische, dokumentarische und touristische Bilder analysiert, die sich der jeweiligen Strahlenkatastrophe oftmals erst Jahre nach dem Ereignis annehmen und ikonografische oder medial-materielle Bezüge zu ihr aufweisen. Es zeigen sich zentrale Strategien, atomare Katastrophen, seien sie militäri...

  9. Tasks of radiation protection in the centralized collection and ultimate disposal of radioactive waste

    Boerst, F.M.; Fasten, C.; Koerner, W.; Oppermann, U.; Werner, H.J.; Zappe, D.

    1988-01-01

    In the GDR, the ERAM (Endlager fuer radioaktive Abfaelle, Morsleben), an operating unit of Volkseigenes Kombinat Kernkraftwerke 'Bruno Leuschner' in Greifswald, is responsible for the central collection and ultimate disposal of radioactive waste. From the licensing body's point of view an assessment is given of the legislation for radioactive wastes, especially as to their collection, transport to and handling in the final repository. As a result, some conclusions are drawn concerning future work in this field. 9 tabs., 34 refs. (author)

  10. A licence to discharge cooling waters in tidal rivers, examplified by the 'Nuclear Power Station Unterweser'

    Kunz, H.

    1976-01-01

    Illustrated by the example of the lower Weser, aspects for automatic control, supervision measurements, and measurements for the securing of evidence, all in connection with cooling water discharges, are presented. The particularities of tidal rivers and the conditions for measuring systems resulting therefrom are explained. The cooling water discharge of the Kernkraftwerk Unterweser has been assigned an extensive measurement system for the automatic compilation of hydrologic data. The measurement systems design, the measurement stations, and the central station are described. (orig.) [de

  11. High resolution inverse synthetic aperture radar imaging of three-axis-stabilized space target by exploiting orbital and sparse priors

    Ma Jun-Tao; Gao Mei-Guo; Xiong Di; Feng Qi; Guo Bao-Feng; Dong Jian

    2017-01-01

    The development of inverse synthetic aperture radar (ISAR) imaging techniques is of notable significance for monitoring, tracking and identifying space targets in orbit. Usually, a well-focused ISAR image of a space target can be obtained in a deliberately selected imaging segment in which the target moves with only uniform planar rotation. However, in some imaging segments, the nonlinear range migration through resolution cells (MTRCs) and time-varying Doppler caused by the three-dimensional rotation of the target would degrade the ISAR imaging performance, and it is troublesome to realize accurate motion compensation with conventional methods. Especially in the case of low signal-to-noise ratio (SNR), the estimation of motion parameters is more difficult. In this paper, a novel algorithm for high-resolution ISAR imaging of a space target by using its precise ephemeris and orbital motion model is proposed. The innovative contributions are as follows. 1) The change of a scatterer projection position is described with the spatial-variant angles of imaging plane calculated based on the orbital motion model of the three-axis-stabilized space target. 2) A correction method of MTRC in slant- and cross-range dimensions for arbitrarily imaging segment is proposed. 3) Coarse compensation for translational motion using the precise ephemeris and the fine compensation for residual phase errors by using sparsity-driven autofocus method are introduced to achieve a high-resolution ISAR image. Simulation results confirm the effectiveness of the proposed method. (paper)

  12. Generation and assessment of turntable SAR data for the support of ATR development

    Cohen, Marvin N.; Showman, Gregory A.; Sangston, K. James; Sylvester, Vincent B.; Gostin, Lamar; Scheer, C. Ruby

    1998-10-01

    Inverse synthetic aperture radar (ISAR) imaging on a turntable-tower test range permits convenient generation of high resolution two-dimensional images of radar targets under controlled conditions for testing SAR image processing and for supporting automatic target recognition (ATR) algorithm development. However, turntable ISAR images are often obtained under near-field geometries and hence may suffer geometric distortions not present in airborne SAR images. In this paper, turntable data collected at Georgia Tech's Electromagnetic Test Facility are used to begin to assess the utility of two- dimensional ISAR imaging algorithms in forming images to support ATR development. The imaging algorithms considered include a simple 2D discrete Fourier transform (DFT), a 2-D DFT with geometric correction based on image domain resampling, and a computationally-intensive geometric matched filter solution. Images formed with the various algorithms are used to develop ATR templates, which are then compared with an eye toward utilization in an ATR algorithm.

  13. Frailty is associated with a history with more falls in elderly hospitalised patients

    Schultz, Martin; Rosted, Elizabeth; Sanders, Suzanne

    2015-01-01

    INTRODUCTION: When elderly people are admitted to hospital, their risk of falling may often not be recognised. The risk of falling in the elderly is linked to frailty. In a Danish study, it was found that the "Identification of Seniors at Risk" screen (ISAR) predicted the patients' amount of health...... problems, days in hospital and readmission. It may therefore also be a predictor of frailty. This study aimed to evaluate how many elderly patients were admitted to an emergency department (ED) because of a fall and to examine if there was a correlation between these patients and their ISAR score. METHODS......: A descriptive cohort study was conducted including patients aged 65 years or older admitted to the ED, n = 198. The following data were collected: ISAR screen, cause of admittance. Furthermore, a retrospective journal review was performed by a specialist in geriatrics. RESULTS: Prior to admission, 31% had...

  14. New inverse synthetic aperture radar algorithm for translational motion compensation

    Bocker, Richard P.; Henderson, Thomas B.; Jones, Scott A.; Frieden, B. R.

    1991-10-01

    Inverse synthetic aperture radar (ISAR) is an imaging technique that shows real promise in classifying airborne targets in real time under all weather conditions. Over the past few years a large body of ISAR data has been collected and considerable effort has been expended to develop algorithms to form high-resolution images from this data. One important goal of workers in this field is to develop software that will do the best job of imaging under the widest range of conditions. The success of classifying targets using ISAR is predicated upon forming highly focused radar images of these targets. Efforts to develop highly focused imaging computer software have been challenging, mainly because the imaging depends on and is affected by the motion of the target, which in general is not precisely known. Specifically, the target generally has both rotational motion about some axis and translational motion as a whole with respect to the radar. The slant-range translational motion kinematic quantities must be first accurately estimated from the data and compensated before the image can be focused. Following slant-range motion compensation, the image is further focused by determining and correcting for target rotation. The use of the burst derivative measure is proposed as a means to improve the computational efficiency of currently used ISAR algorithms. The use of this measure in motion compensation ISAR algorithms for estimating the slant-range translational motion kinematic quantities of an uncooperative target is described. Preliminary tests have been performed on simulated as well as actual ISAR data using both a Sun 4 workstation and a parallel processing transputer array. Results indicate that the burst derivative measure gives significant improvement in processing speed over the traditional entropy measure now employed.

  15. A method for manufacturing a hollow mems structure

    2017-01-01

    The present invention relates to a method for manufacturing an at least partly hollow MEMS structure. In a first step one or more through-going openings is/are provided in core material. The one or more through-going openings is/are then covered by an etch-stop layer. After this step, a bottom...... further comprises the step of creating bottom and top conductors in the respective bottom and top layers. Finally, excess core material is removed in order to create the at least partly hollow MEMS structure which may include a MEMS inductor....

  16. Development of a Near-Field Bistatic Synthetic Aperture Radar for Complex Target Reconstruction

    David G. Johnson

    2012-01-01

    Full Text Available This paper begins with a description of the design, construction, and characterization of a small electromagnetic anechoic chamber, developed specifically to house a bistatic ISAR system for the analysis of rock samples. Particular emphasis is given to the practicalities of construction, with the intention of assisting those in a similar position, wishing to build an anechoic chamber on a tight budget. The second part of the paper outlines efficient algorithms that may be applied to the tomographic and topographic reconstruction of complex targets within the viewing geometry of this ISAR system.

  17. Hamor-2: a computer code for LWR inventory calculation

    Guimaraes, L.N.F.; Marzo, M.A.S.

    1985-01-01

    A method for calculating the accuracy inventory of LWR reactors is presented. This method uses the Hamor-2 computer code. Hamor-2 is obtained from the coupling of two other computer codes Hammer-Techion and Origen-2 for testing Hamor-2, its results were compared to concentration values measured from activides of two PWR reactors; Kernkraftwerk Obrighein (KWO) and H.B. Robinson (HBR). These actinides are U 235 , U 236 , U 238 , Pu 239 , Pu 241 and PU 242 . The computer code Hammor-2 shows better results than the computer code Origem-2, when both are compared with experimental results. (E.G.) [pt

  18. Objectives and present status of the German risk evaluation study

    Birkhofer, A.; Koeberlein, K.; Heuser, F.W.

    1977-01-01

    For the German risk evaluation study, analogous to the Rasmussen report (WASH--1400), embarked upon in June 1976, the Kernkraftwerk Biblis B serves as the plant of reference. The first interim results are available for various sub-headings of the study. The main finding seems to be the decisive importance of the containment in limiting the accident consequences even in those cases where, on account of postulated failure of safety systems, the melt down of the reactor core is to be expected. (orig./HP) [de

  19. In-situ, real-time, studies of film growth processes using ion scattering and direct recoil spectroscopy techniques.

    Smentkowski, V. S.

    1999-04-22

    Time-of-flight ion scattering and recoil spectroscopy (TOF-ISARS) enables the characterization of the composition and structure of surfaces with 1-2 monolayer specificity. It will be shown that surface analysis is possible at ambient pressures greater than 3 mTorr using TOF-ISARS techniques; allowing for real-time, in situ studies of film growth processes. TOF-ISARS comprises three analytical techniques: ion scattering spectroscopy (ISS), which detects the backscattered primary ion beam; direct recoil spectroscopy (DRS), which detects the surface species recoiled into the forward scattering direction; and mass spectroscopy of recoiled ions (MSRI), which is 3 variant of DRS capable of isotopic resolution for all surface species--including H and He. The advantages and limitations of each of these techniques will be discussed. The use of the three TOF-ISARS methods for real-time, in situ film growth studies at high ambient pressures will be illustrated. It will be shown that MSRI analysis is possible during sputter deposition. It will be also be demonstrated that the analyzer used for MSRI can also be used for time of flight secondary ion mass spectroscopy (TOF-SIMS) under high vacuum conditions. The use of a single analyzer to perform the complimentary surface analytical techniques of MSRI and SIMS is unique. The dwd functionality of the MSRI analyzer provides surface information not obtained when either MSRI or SIMS is used independently.

  20. The Identification of Seniors at Risk screening tool is useful for predicting acute readmissions

    Rosted, Elizabeth; Schultz, Martin; Dynesen, Helle

    2014-01-01

    . Patients ≥ 65 years treated during a 14-day period were included. Their mean age was 78 years. Screening with the Identification of Seniors at Risk (ISAR) was performed (n = 198) by the Mobile Geriatric Team (MGT). The patients' medical journals were assessed retrospectively by the SG to determine any need...

  1. A clarion call for aeolian research to engage with global land degradation and climate change

    Chappell, Adrian; Lee, Jeffrey A.; Baddock, Matthew; Gill, Thomas E.; Herrick, Jeffrey E.; Leys, John F.; Marticorena, Beatrice; Petherick, Lynda; Schepanski, Kerstin; Tatarko, John; Telfer, Matt; Webb, Nicholas P.

    2018-06-01

    This editorial represents a clarion call for the aeolian research community to provide increased scientific input to the Intergovernmental Panel on Climate Change (IPCC) and the United Nations Convention to Combat Desertification (UNCCD) and an invitation to apply for ISAR funding to organize a working group to support this engagement.

  2. Logarithmic Laplacian Prior Based Bayesian Inverse Synthetic Aperture Radar Imaging

    Shuanghui Zhang

    2016-04-01

    Full Text Available This paper presents a novel Inverse Synthetic Aperture Radar Imaging (ISAR algorithm based on a new sparse prior, known as the logarithmic Laplacian prior. The newly proposed logarithmic Laplacian prior has a narrower main lobe with higher tail values than the Laplacian prior, which helps to achieve performance improvement on sparse representation. The logarithmic Laplacian prior is used for ISAR imaging within the Bayesian framework to achieve better focused radar image. In the proposed method of ISAR imaging, the phase errors are jointly estimated based on the minimum entropy criterion to accomplish autofocusing. The maximum a posterior (MAP estimation and the maximum likelihood estimation (MLE are utilized to estimate the model parameters to avoid manually tuning process. Additionally, the fast Fourier Transform (FFT and Hadamard product are used to minimize the required computational efficiency. Experimental results based on both simulated and measured data validate that the proposed algorithm outperforms the traditional sparse ISAR imaging algorithms in terms of resolution improvement and noise suppression.

  3. Dehumanization and Education.

    Pekarsky, Daniel

    1982-01-01

    Two types of dehumanization are defined, and modern instances of dehumanization--failure to regard a person as if s/he were the human being that s/he is--are analyzed. Philosophical insights of Immanuel Kant and Martin Buber concerning human dignity are given, and examples of dehumanization in education are cited. (PP)

  4. The island species–area relationship

    Triantis, Kostas A.; Guilhaumon, François; Whittaker, Robert J.

    2012-01-01

    , and shape, and for the presence/absence of an asymptote. Two main criteria were applied: generality (the proportion of cases for which the model provided an adequate fit) and efficiency (the overall probability of a model, when adequate, being the best at explaining ISARs; evaluated using the mean overall...

  5. Fermat and the Minimum Principle

    Arguably, least action and minimum principles were offered or applied much earlier. This (or these) principle(s) is/are among the fundamental, basic, unifying or organizing ones used to describe a variety of natural phenomena. It considers the amount of energy expended in performing a given action to be the least required ...

  6. The use of specialised enteral formulae for patients with diabetes ...

    Does this have short- and long-term benefits and which component(s) is/are ... an enhanced fibre intake in the diet, it should be remembered that modified fibres are ... Studies comparing diabetes-specific formulae with standard formulae have ... most commonly encountered complications in these cases. Fibre containing ...

  7. Site suitability analysis and route optimization for solid waste ...

    Solid waste management system is a tedious task that is facing both developing and developed countries. Site Suitability analysis and route optimization for solid waste disposal can make waste management cheap and can be used for sustainable development. However, if the disposal site(s) is/are not sited and handle ...

  8. Prostate Cancer Disparities in an Incarcerated Community

    2013-09-01

    diseases, Liver diseases, Cerebrovascular accident , non-Illnesses, and finally AIDS. 30% of inmates incarcerated in the WDOC die from Cancer while it is...are higher among WDOC inmates than the general U.S. population; while Cerebrovascular Accidents (CVA) are lower among WDOC inmates than the general

  9. The Role of Relational and Instructional Classroom Supports in the Language Development of At-Risk Preschoolers

    Gosse, Carolyn S.; McGinty, Anita S.; Mashburn, Andrew J.; Hoffman, LaVae M.; Pianta, Robert C.

    2014-01-01

    The present study examined the extent to which preschool classroom supports--relational support (RS) and instructional support (IS)--are associated with children's language development and whether these associations vary as a function of children's language ability. The language skills of 360 children within 95 classrooms were assessed using an…

  10. Investigation of hopped frequency waveforms for range and velocity measurements of radar targets

    Kathree, U

    2015-10-01

    Full Text Available In the field of radar, High Range Resolution (HRR) profiles are often used to improve target tracking accuracy in range and to allow the radar system to produce an image of an object using techniques such as inverse synthetic aperture radar (ISAR...

  11. Research on the development of space target detecting system and three-dimensional reconstruction technology

    Li, Dong; Wei, Zhen; Song, Dawei; Sun, Wenfeng; Fan, Xiaoyan

    2016-11-01

    With the development of space technology, the number of spacecrafts and debris are increasing year by year. The demand for detecting and identification of spacecraft is growing strongly, which provides support to the cataloguing, crash warning and protection of aerospace vehicles. The majority of existing approaches for three-dimensional reconstruction is scattering centres correlation, which is based on the radar high resolution range profile (HRRP). This paper proposes a novel method to reconstruct the threedimensional scattering centre structure of target from a sequence of radar ISAR images, which mainly consists of three steps. First is the azimuth scaling of consecutive ISAR images based on fractional Fourier transform (FrFT). The later is the extraction of scattering centres and matching between adjacent ISAR images using grid method. Finally, according to the coordinate matrix of scattering centres, the three-dimensional scattering centre structure is reconstructed using improved factorization method. The three-dimensional structure is featured with stable and intuitive characteristic, which provides a new way to improve the identification probability and reduce the complexity of the model matching library. A satellite model is reconstructed using the proposed method from four consecutive ISAR images. The simulation results prove that the method has gotten a satisfied consistency and accuracy.

  12. Unconsummated Marriage in Sub-Saharan Africa: Case Reports ...

    Unconsummated marriage is a condition where newly married couples are unable to achieve penile-vaginal intercourse for variable periods despite desire and several attempts to do so. Its exact cause(s) is/are unknown, but performance anxiety resulting from or leading to other conditions is reportedly the major etiological ...

  13. Integrating Mobile Technologies into Very Young Second Language Learners' Curriculum

    Sadykova, Gulnara; Gimaletdinova, Gulnara; Khalitova, Liliia; Kayumova, Albina

    2016-01-01

    This report is based on an exploratory case study of a private multilingual preschool language program that integrated a Mobile-Assisted Language Learning (MALL) project into the curriculum of five/six year-old children whose native language(s) is/are Russian and/or Tatar. The purpose of the study was to reveal teachers' and parents' perceptions…

  14. D1+ Simulator: A cost and risk optimized approach to nuclear power plant simulator modernization

    Wischert, W.

    2006-01-01

    D1-Simulator is operated by Kraftwerks-Simulator-Gesellschaft (KSG) and Gesellschaft f?r Simulatorschulung (GfS) at the Simulator Centre in Essen since 1977. The full-scope control room training simulator, used for Kernkraftwerk Biblis (KWB) is based on a PDP-11 hardware platform and is mainly programmed in ASSEMBLER language. The Simulator has reached a continuous high availability of operation throughout the years due to specialized hardware and software support from KSG maintenance team. Nevertheless, D1-Simulator largely reveals limitations with respect to computer capacity and spares and suffers progressively from the non-availability of hardware replacement materials. In order to ensure long term maintainability within the framework of the consensus on nuclear energy, a 2-years refurbishing program has been launched by KWB focusing on quality and budgetary aspects. The so-called D1+ Simulator project is based on the re-use of validated data from existing simulators. Allowing for flexible project management methods, the project outlines a cost and risk optimized approach to Nuclear Power Plant (NPP) Simulator modernization. D1+ Simulator is being built by KSG/GfS in close collaboration with KWB and the simulator vendor THALES by re-using a modern hardware and software development environment from D56-Simulator, used by Kernkraftwerk Obrigheim (KWO) before its decommissioning in 2005. The Simulator project, launched in 2004, is expected to be completed by end of 2006. (author)

  15. Evaluation of load case ``switch-off of the high pressure pump of the emergency core cooling system``, measures of verification and in situ-test; Einstufung des Lastfalls ``Ausfall der TH-Hochdruckeinspeisepumpe``, Massnahmen zur Verifikation bis hin zum Grossversuch

    Trobitz, M.; Mattheis, A. [Kernkraftwerke Gundremmingen Betriebsgesellschaft m.b.H. (Germany); Kerkhof, K.; Hippelein, K. [Stuttgart Univ. (Germany). Staatliche Materialpruefungsanstalt; Gurr-Beyer, C. [Buero fuer Baudynamik, Stuttgart (Germany); Hofstoetter, P. [Technischer Ueberwachungs-Verein Rheinland e.V., Koeln (Germany)

    1998-11-01

    Within the framework of periodic safety inspection of the Gundremmingen power station (RWE-Bayernwerk - KRB II), the load collectives used for the design of safety-relevant systems and components were checked for their consistency with latest updates of the design basis. It was found that there was no analytical information or study available describing a particular process and its effects, namely switch-off of the high-pressure feedwater pump of the emergency core cooling system. The paper reports the work performed for closing the gap, including preparatory analyses, accompanying measures such as vibration measurements during plant shut-down, as well as the preparation and performance of the in-situ test. The experimental results and the comparative evaluation of calculated and experimental data are presented. (orig./CB) [Deutsch] Im Rahmen der periodischen Sicherheitsueberpruefung des Kernkraftwerkes Gundremmingen (Kernkraftwerke RWE-Bayernwerk - KRB II) wurden u.a. die Lastkollektive, die zur Auslegung sicherheitstechnisch relevanter Systeme und Komponenten herangezogen wurden, auf Aktualitaet ueberprueft. Dabei zeigte sich, dass bislang fuer eine Betriebsweise - naemlich das Abschalten der Hochdruckeinspeisepumpe des nuklearen Not- und Nachkuehlsystems (TH-HD-Pumpe) - keine analytischen Untersuchungen vorliegen. Vorbetrachtungen fuer analytische Untersuchungen, begleitende Massnahmen wie Schwingungsmessungen waehrend des Anlagenstillstandes, sowie der Versuchsaufbau und die Versuchsdurchfuehrung des Anlagenversuches werden hier dargestellt. Die Ergebnisse und der Vergleich Rechnung-Messung zum Grossversuch werden in diesem Beitrag vorgestellt. (orig.)

  16. [Screening of the risk of functional decline performed by an inpatient geriatric consultation team in a general hospital].

    Benoît, F; Bertiaux, M; Schouterden, R; Huard, E; Segers, K; Decorte, L; Robberecht, J; Simonetti, C; Surquin, M

    2013-01-01

    The Mobile Geriatric Team (MGT) is part of the Geriatric Care Program and aims to provide interdisciplinary geriatric expertise to other professionals for old patients hospitalized outside geriatric department. Our hospital has a MGT since 2008. Our objective is to retrospectively describe the population of patients of 75 years and older hospitalized outside the geriatric ward and screened for the risk of functional decline by the MGT between 1 October 2009 and 30 September 2011. We recorded the risk of functional decline, as indicated by the Identification of Senior At Risk score (ISAR) performed within 48 h after admission, place of living, discharge destination, Mini Mental State Examination (MMSE) and Geriatric Depression Scale (GDS) scores. In two years, 1.568 patients > or = 75 Y were screened with the ISAR score (mean age 82.5 Y, 60.7% of women). We identified 833 patients with a high-risk of functional decline (ISAR > or = 3). The majority of high-risk subjects (78%) were living at home before hospitalization and 58.7% returned home after discharge. Depression and cognitive impairment were identified among respectively 41% and 59% of high-risk subjects. Only 128 patients were admitted for fall. Most of the faller patients were living at home prior hospitalization and had an ISAR score > or = 3. The MGT allowed identifying many patients > or = 75 Y living at home and presenting with high-risk of functional decline and geriatric syndromes, confirming that good screening procedures are necessary to optimize management of hospitalized olders. Most of faller patients have an ISAR score > or = 3 and should benefit a comprehensive geriatric assessment.

  17. Frailty is associated with a history with more falls in elderly hospitalised patients.

    Schultz, Martin; Rosted, Elizabeth; Sanders, Suzanne

    2015-06-01

    When elderly people are admitted to hospital, their risk of falling may often not be recognised. The risk of falling in the elderly is linked to frailty. In a Danish study, it was found that the "Identification of Seniors at Risk" screen (ISAR) predicted the patients' amount of health problems, days in hospital and readmission. It may therefore also be a predictor of frailty. This study aimed to evaluate how many elderly patients were admitted to an emergency department (ED) because of a fall and to examine if there was a correlation between these patients and their ISAR score. A descriptive cohort study was conducted including patients aged 65 years or older admitted to the ED, n = 198. The following data were collected: ISAR screen, cause of admittance. Furthermore, a retrospective journal review was performed by a specialist in geriatrics. Prior to admission, 31% had experienced a fall. Of those, 67% were not referred for further fall assessment. Patients who had experienced falls had more health problems than patients without falls (mean 5.7 versus mean 4.4 (p = 0.00)) and more had cognitive impairment (31% versus 14% (p = 0.00)). A positive correlation was found between patients' ISAR score and falls (p = 0.03). To prevent further falls and readmissions, it is crucial not only to focus on elderly people's presenting problems, but also on their dizziness and falls, especially in cognitively impaired elderly patients, and to make a plan for further assessment and follow-up. We suggest the ISAR screen as a supplement to measurement of vital signs as it may predict frailty and falls. not relevant.

  18. Predictive validity of the identification of seniors at risk screening tool in a German emergency department setting.

    Singler, Katrin; Heppner, Hans Jürgen; Skutetzky, Andreas; Sieber, Cornel; Christ, Michael; Thiem, Ulrich

    2014-01-01

    The identification of patients at high risk for adverse outcomes [death, unplanned readmission to emergency department (ED)/hospital, functional decline] plays an important role in emergency medicine. The Identification of Seniors at Risk (ISAR) instrument is one of the most commonly used and best-validated screening tools. As to the authors' knowledge so far there are no data on any screening tool for the identification of older patients at risk for a negative outcome in Germany. To evaluate the validity of the ISAR screening tool in a German ED. This was a prospective single-center observational cohort study in an ED of an urban university-affiliated hospital. Participants were 520 patients aged ≥75 years consecutively admitted to the ED. The German version of the ISAR screening tool was administered directly after triage of the patients. Follow-up telephone interviews to assess outcome variables were conducted 28 and 180 days after the index visit in the ED. The primary end point was death from any cause or hospitalization or recurrent ED visit or change of residency into a long-term care facility on day 28 after the index ED visit. The mean age ± SD was 82.8 ± 5.0 years. According to ISAR, 425 patients (81.7%) scored ≥2 points, and 315 patients (60.5%) scored ≥3 points. The combined primary end point was observed in 250 of 520 patients (48.1%) on day 28 and in 260 patients (50.0%) on day 180. Using a continuous ISAR score the area under the curve on day 28 was 0.621 (95% confidence interval, CI 0.573-0.669) and 0.661 (95% CI 0.615-0.708) on day 180, respectively. The German version of the ISAR screening tool acceptably identified elderly patients in the ED with an increased risk of a negative outcome. Using the cutoff ≥3 points instead of ≥2 points yielded better overall results.

  19. Flood-proof motors

    Schmitt, Marcus [AREVA NP GmbH, Erlangen (Germany)

    2013-07-01

    Even before the Fukushima event occurred some German nuclear power plants (NPP) have considered flooding scenarios. As a result of one of these studies, AREVA performed an upgrade project in NPP Isar 1 with flood-proof motors as a replacement of existing air-cooled low-voltage and high-voltage motors of the emergency cooling chain. After the Fukushima event, in which the cooling chains failed, the topic flood-proof equipment gets more and more into focus. This compact will introduce different kinds of flood-proof electrical motors which are currently installed or planned for installation into NPPs over the world. Moreover the process of qualification, as it was performed during the project in NPP Isar 1, will be shown. (orig.)

  20. Decontamination by water jet, chemical and electrochemical methods

    Gauchon, J.P.; Mordenti, P.; Bezia, C.; Fuentes, P.; Kervegant, Y.; Munoz, C.; Pierlas, C.

    1986-01-01

    The decontamination tests have been carried out on samples coming from representative specimens from primary circuit of the PWR and on samples coming from the emergency feed water piping of the German BWR (Isar). The oxide found in PWR primary loops can only be removed by a two steps process. The initial embrittling step is particularly effective in hot alkaline permanganate medium. Oxidation by ozone treatment is less effective. The second step involves chemical erosion of the metal in nitrofluoric acid in conjonction with ultrasonic agitation. Among the reagents used, only oxalic acid is suitable for electrolytic decontamination. Among the reagents possible for decontamination of the Isar specimens (ferritic steel lined with hematite) halogenous acid in mixture without or with oxygenated water, sulfuric acid, the formic acid/formaldehyde mixture are chosen. Metal erosion with high pressure jet as well as the decontamination efficiency on parts lined with hematite have made possible to determine the best conditions. 33 figs, 29 refs

  1. Radiation hygienic annual report 2012. General environmental radioactivity and radiation surveillance in the vicinity of nuclear facilities in Bavaria

    Pfau, T.; Bernkopf, J.; Klement, R.; Bayerisches Landesamt fuer Umwelt, Augsburg

    2013-01-01

    The radiation hygienic annual report 2012 includes the following issues: (1) Introduction: Legal aspects of the surveillance, implementation of the radiation protection law, nuclear facility sites in Bavaria, interim storage facilities in Bavaria. (2) Natural radioactivity surveillance: measured data for the exposure paths air, water, food chain land, food chain water, residuals and waste. (3) Radiation surveillance in the vicinity of nuclear facilities in Bavaria: measures for air, precipitation, soils, plants, food chain land, milk and milk products, surface water, food chain water, drinking and ground water; measured data in the vicinity of NNP Isar 1 bd Isar 2 (KKI1/KKI2), NPP Gundremmingen (KGG), NPP Grafenrheinfeld (KKG), research neutron source Muenchen FRM II; emissions, meteorological conditions, spreading calculations.

  2. Higher Education Language Policy

    Lauridsen, Karen M.

    2013-01-01

    Summary of recommendations HEIs are encouraged, within the framework of their own societal context, mission, vision and strategies, to develop the aims and objectives of a Higher Education Language Policy (HELP) that allows them to implement these strategies. In this process, they may want......: As the first step in a Higher Education Language Policy, HEIs should determine the relative status and use of the languages employed in the institution, taking into consideration the answers to the following questions:  What is/are the official language(s) of the HEI?  What is/are the language...... and the level of internationalisation the HEI has or wants to have, and as a direct implication of that, what are the language proficiency levels expected from the graduates of these programme?  Given the profile of the HEI and its educational strategies, which language components are to be offered within...

  3. Efficient moving target analysis for inverse synthetic aperture radar images via joint speeded-up robust features and regular moment

    Yang, Hongxin; Su, Fulin

    2018-01-01

    We propose a moving target analysis algorithm using speeded-up robust features (SURF) and regular moment in inverse synthetic aperture radar (ISAR) image sequences. In our study, we first extract interest points from ISAR image sequences by SURF. Different from traditional feature point extraction methods, SURF-based feature points are invariant to scattering intensity, target rotation, and image size. Then, we employ a bilateral feature registering model to match these feature points. The feature registering scheme can not only search the isotropic feature points to link the image sequences but also reduce the error matching pairs. After that, the target centroid is detected by regular moment. Consequently, a cost function based on correlation coefficient is adopted to analyze the motion information. Experimental results based on simulated and real data validate the effectiveness and practicability of the proposed method.

  4. High-resolution imaging using a wideband MIMO radar system with two distributed arrays.

    Wang, Dang-wei; Ma, Xiao-yan; Chen, A-Lei; Su, Yi

    2010-05-01

    Imaging a fast maneuvering target has been an active research area in past decades. Usually, an array antenna with multiple elements is implemented to avoid the motion compensations involved in the inverse synthetic aperture radar (ISAR) imaging. Nevertheless, there is a price dilemma due to the high level of hardware complexity compared to complex algorithm implemented in the ISAR imaging system with only one antenna. In this paper, a wideband multiple-input multiple-output (MIMO) radar system with two distributed arrays is proposed to reduce the hardware complexity of the system. Furthermore, the system model, the equivalent array production method and the imaging procedure are presented. As compared with the classical real aperture radar (RAR) imaging system, there is a very important contribution in our method that the lower hardware complexity can be involved in the imaging system since many additive virtual array elements can be obtained. Numerical simulations are provided for testing our system and imaging method.

  5. Receptor binding radiotracers for the angiotensin II receptor: radioiodinated [Sar1, Ile8]angiotensin II

    Gibson, R.E.; Beauchamp, H.T.; Fioravanti, C.; Brenner, N.; Burns, H.D.

    1994-01-01

    The potential for imaging the angiotensin II receptor was evaluated using the radioiodinated peptide antagonist [ 125 I][Sar 1 , Ile 8 ]angiotensin II. The radioligand provides a receptor-mediated signal in several tissues in rat (kidneys, adrenal and liver). The receptor-mediated signal of 3% ID/g kidney cortex should be sufficient to permit imaging, at least via SPECT. The radiotracer is sensitive to reductions in receptor concentration and can be used to define in vivo dose-occupancy curves of angiotensin II receptor ligands. Receptor-mediated images of [ 123 I][Sar 1 , Ile 8 ]angiotensin II were obtained in the rat kidney and Rhesus monkey liver. (author)

  6. Flood-proof motors

    Schmitt, Marcus

    2013-01-01

    Even before the Fukushima event occurred some German nuclear power plants (NPP) have considered flooding scenarios. As a result of one of these studies, AREVA performed an upgrade project in NPP Isar 1 with flood-proof motors as a replacement of existing air-cooled low-voltage and high-voltage motors of the emergency cooling chain. After the Fukushima event, in which the cooling chains failed, the topic flood-proof equipment gets more and more into focus. This compact will introduce different kinds of flood-proof electrical motors which are currently installed or planned for installation into NPPs over the world. Moreover the process of qualification, as it was performed during the project in NPP Isar 1, will be shown. (orig.)

  7. Hybrid cooling tower Neckarwestheim 2 cooling function, emission, plume dispersion

    Braeuning, G.; Ernst, G.; Maeule, R.; Necker, P.

    1990-01-01

    The fan-assisted hybrid cooling tower of the 1300 MW power plant Gemeinschafts-Kernkraftwerk Neckarwestheim 2 was designed and constructed based on results from theoretical and experimental studies and experiences from a smaller prototype. The wet part acts in counterflow. The dry part is arranged above the wet part. Each part contains 44 fans. Special attention was payed to the ducts which mix the dry into the wet plume. The cooling function and state, mass flow and contents of the emission were measured. The dispersion of the plume in the atmosphere was observed. The central results are presented in this paper. The cooling function corresponds to the predictions. The content of drifted cooling water in the plume is extremely low. The high velocity of the plume in the exit causes an undisturbed flow into the atmosphere. The hybrid operation reduces visible plumes strongly, especially in warmer and drier ambient air

  8. The Chernobyl reactor accident, ten years on. Teaching projects for mathematics instruction in interdisciplinary working groups; 10 Jahre nach Tschernobyl. Unterrichtsprojekte fuer den Mathematikunterricht in faecheruebergreifenden Kooperationen

    Boer, H. [comp.; Delle, E. [comp.; Mies, K. [comp.; Warmeling, A. [comp.

    1996-10-01

    The booklet presents background information and addresses the following aspects: ionizing radiation and radiation effects; safety of German nuclear power plants; statistical evidence of radiation injuries; short-lived and long-lived ionizing radiation; radioactive waste; CO{sub 2} emissions as an argument in favour of nuclear power generation. The material presented is intended for use by a school project team interested in the subjects, or as a basis for collaborative, interdisciplinary teaching in working groups, and it offers information and problems for mathematics teaching. (HP) [Deutsch] Neben vielen Informationen behandelt die Broschuere: Strahlen und Strahlenwirkungen; Sicherheit deutscher Kernkraftwerke; statistischer Nachweis von Strahlenschaeden; Kurz- und Langfestigkeit der Strahlenbelastung; radioaktiver Abfall; CO{sub 2}-Problematik als Argument fuer die Kernenergie. Die Broschuere ist gedacht z.B. fuer eine Projektgruppe, einen Projekttag, fuer eine Lerngruppe in faecheruebergreifender Kooperation. Die Materialien sind ausgearbeitet fuer die Themembearbeitung im Mathematikunterricht mit Uebungsaufgaben. (HP)

  9. Contributions to economical and safe operation of nuclear power plants

    Ackermann, G.; Meyer, K.

    1989-01-01

    Selected results of scientific and technical research works in the Department 'Nuclear Power' of the Zittau Technical University are summarized which have been obtained on behalf of the Kombinat Kernkraftwerke 'Bruno Leuschner' and in conjunction with the education of scientific successors and have been partly adopted in textbooks. Works on improved utilization of nuclear fuel in pressurized water reactors are mentioned which, among other things, are related with the use of stretch-out mode of operation and optimization of nuclear fuel loading sequence. Results of experimental and theoretical investigations on coolant mixing in the reactor core are presented. A complex modelling of the dynamical long-term behaviour of nuclear power plants with pressurized water reactors due to xenon poisoning are briefly described. Finally, some results on noise diagnostics theory of power reactors are summarized. (author)

  10. Federal Administrative Court on priorities between water law and nuclear law procedures

    Anon.

    1980-01-01

    With its decision of November 22, 1979 - BVerwG 4 B 162/79 -, the Federal Administration Court, at the expense of the plaintiff, has judged against a Bremen resident who had lodged a complained against the non-admission of an appeal in a partial verdict by the Lueneburg Higher Administrative Court concerning licenses under water law for Kernkraftwerk Unterweser. The value in litigation for the complaint procedure was set at DM 5000,-. In its partial verdict of February 12, 1979 - VII OVG A 113/77 - the Lueneburg Higher Administrative Court had decided that the plaintiff's rights are not infringed by the administrative steps under water law taken by the defendant district, and that pleas under nuclear law cannot be entered in the present procedure. The Federal Administrative Court was of the same opinion. The reasons for its decision are given in full wording. (orig./HP) 891 HP/orig.- 892 CKA [de

  11. German study on the risks of nuclear power plants

    Wollny, V.

    1987-01-01

    The 'Deutsche Risikostudie Kernkraftwerke', DRS, (German study on the risks of nuclear plants) calculates a frequency of 1/10000 years (i.e. once in 10000 years of reactor operation) for the event of insufficient cooling of the reactor core occurring. The resulting collective risk is put at approximately 10 deaths per year for 25 plants. As the explanations show, the error margin of such a risk statement is enormous. Moreover, much seems to indicate that the risk was underrated. Apart from this, risk analyses are of doubtful value in the decision process for or against the introduction of large-scale technologies. They cannot replace the individual decision of all concerned. (orig./HSCH) [de

  12. Evidos: optimisation of individual monitoring in mixed neutron/photon fields at workplaces of the nuclear fuel cycle

    Luszik-Bhadra, M.; Reginatto, M.; Schuhmacher, H.; Lacoste, V.; Muller, M.; Boschung, M.; Fiechtner, A.; Coeck, M.; Vanhavere, F.; Curzio, G.; D'errico, F.; Kyllonen, J.E.; Lindborg, L.; Molinos, C.; Tanner, R.; Derdau, D.; Lahaye, Th.

    2005-01-01

    Within its 5. Framework Programme, the EC is funding the project EVIDOS ('Evaluation of Individual Dosimetry in Mixed Neutron and Photon Radiation Fields'). The aim of this project is the optimisation of individual monitoring at workplaces of the nuclear fuel cycle with special regard to neutrons. Various dosemeters for mixed field application - passive and new electronic devices - are tested in selected workplace fields in nuclear installations in Europe. The fields are characterised using a series of spectrometers that provide the energy distribution of neutron fluence (Bonner spheres) and newly developed devices that provide the energy and directional distribution of the neutron fluence. Results from the first measurement campaign, carried out in simulated workplace fields (IRSN, Cadarache. France), and those of a second measurement campaign, carried out at workplaces at a boiling water reactor and at a storage cask with used fuel elements (Kernkraftwerk Kriimmel, Germany), are described. (authors)

  13. Comparison of plant-specific probabilistic safety assessments and lessons learned

    Balfanz, H.P. [TUeV Nord, Hamburg (Germany); Berg, H.P. [Bundesamt fuer Strahlenschutz, Salzgitter (Germany); Steininger, U. [TUeV Energie- und Systemtechnik GmbH, Unternehmensgruppe TUeV Sueddeutschland, Muenchen (Germany)

    2001-11-01

    Probabilistic safety assessments (PSA) have been performed for all German nuclear power plants in operation. These assessments are mainly based on the recent German PSA guide and an earlier draft, respectively. However, comparison of these PSA show differences in the results which are discussed in this paper. Lessons learned from this comparison and further development of the PSA methodology are described. (orig.) [German] Probabilistische Sicherheitsanalysen (PSA) sind fuer alle in Betrieb befindlichen deutschen Kernkraftwerke durchgefuehrt worden. Diese Analysen basierten in der Regel auf dem aktuellen deutschen PSA-Leitfaden bzw. einem frueheren Entwurf. Ein Vergleich dieser PSA zeigt Unterschiede in den Ergebnissen, die in diesem Beitrag diskutiert werden. Erfahrungen und Erkenntnisse, die aus diesem Vergleich abgeleitet werden koennen, und weitere Entwicklungen der PSA-Methoden werden beschrieben. (orig.)

  14. A current perspective on the risk significance of steam explosions

    Snyder, A.W.

    1982-01-01

    The view currently held in the Sandia National Laboratory is that, in the case of a meltdown in the reactor core, the probability of a steam explosion is greater than was estimated in WASH-1400, but that the extent and effect of an explosion will be very much smaller than assumed in WASH-1400. This results in a far smaller total risk with regard to containment. In WASH-1400, a nominal conditional probability of 1% was assumed for a containment rupture in a PWR-type reactor, should a large part of the reactor fuel be subject to meltdown during the course of the accident. The German risk analysis study 'Deutsche Risikostudie Kernkraftwerke' dated 1979 considers an explosion of a size sufficient to represent a threat to containment to be considerably more improbable than was assumed in WASH-1400. (orig./DG) [de

  15. Rotation Estimation for Wide-Angle Inverse Synthetic Aperture Radar Imaging

    Wei Zhou

    2016-01-01

    Full Text Available To present focused ISAR imaging results in the homogenous range and cross-range domain, an integrated scheme is proposed to estimate both the targets equivalent rotational velocity (RV and rotational center (RC. The RV estimation is improved by radial projection combined with keystone processing, and then the RC is estimated through image entropy minimization. Finally, delicate imaging results may be obtained for wide-angle scenarios. Experiment results are provided to demonstrate the effectiveness of the proposed method.

  16. Determination of the Minimum Use Level of Fuel System Icing Inhibitor (FSII) in JP-8 That Will Provide Adquate Icing Inhibition and Biostatic Protection for Air Force Aircraft

    2013-12-01

    filter element or specific component when subjected to ice blockage . This condition was referred to as “Component Testing” in the previous version...of the ARP (SAE ARP 1401A). For evaluation of a FSII effectiveness to prevent blockage due to icing, the Filter Bypass Function Operation regime is...are well- maintained. Once the fuel is on-board the aircraft, the only viable mechanism for water to enter the aircraft is by condensation of water

  17. Geospatial Authentication

    Lyle, Stacey D.

    2009-01-01

    A software package that has been designed to allow authentication for determining if the rover(s) is/are within a set of boundaries or a specific area to access critical geospatial information by using GPS signal structures as a means to authenticate mobile devices into a network wirelessly and in real-time. The advantage lies in that the system only allows those with designated geospatial boundaries or areas into the server.

  18. Nuclear energy demon

    Ruckdeschel, W.

    1980-01-01

    The German nuclear power plants (here Grafenrheinfeld, Isar) dispose of large-scale provisions echeloned in depth against release of activity due to incidents. According to human judgement environmental risks can be excluded. The direct risk is explained in the Rasmussen-study and in the German Risk Study Nuclear Power Plants. The Inhaber-study represents an important contribution to the risk assessment. (DG) [de

  19. Biological detector and method

    Sillerud, Laurel; Alam, Todd M; McDowell, Andrew F

    2013-02-26

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  20. ANTIMICROBIALS USED IN ACTIVE PACKAGING FILMS

    Dıblan, Sevgin; Kaya, Sevim

    2017-01-01

    Active packaging technology is one of the innovativemethods for preserving of food products, and antimicrobial packaging films is amajor branch and promising application of this technology. In order to controlmicrobial spoilage and also contamination of pathogen onto processed or fresh food,antimicrobial agent(s) is/are incorporated into food packaging structure.Polymer type as a carrier of antimicrobial can be petroleum-based plastic orbiopolymer: because of environmental concerns researcher...

  1. The use of specialised enteral formulae for patients with diabetes ...

    The majority of enteral nutrition products for diabetes mellitus have a carbohydrate content of 30–45% and fat between 40–49%, mainly monounsaturated fat, with a mix of soluble and insoluble fibre (total of 14–24 g/l). Does this have short- and long-term benefits and which component(s) is/are crucial for the outcome or is it ...

  2. Spatial patterns of tree species distribution in New Guinea primary and secondary lowland rain forest

    Fibich, P.; Lepš, Jan; Novotný, Vojtěch; Klimeš, Petr; Těšitel, J.; Molem, K.; Damas, K.; Weiblen, G. D.

    2016-01-01

    Roč. 27, č. 2 (2016), s. 328-339 ISSN 1100-9233 R&D Projects: GA ČR(CZ) GA14-04258S Grant - others:European Social Fund(CZ) CZ.1.07/2.3.00/20.0064 Institutional support: RVO:60077344 Keywords : ISAR * null model * Papua New Guinea Subject RIV: EH - Ecology, Behaviour Impact factor: 2.924, year: 2016 http://onlinelibrary.wiley.com/doi/10.1111/jvs.12363/abstract

  3. Safety assessment of the BELENE NPP

    Bruna, G.B.

    2010-01-01

    The most important outcome of the RISKAUDIT’s review of the BELENE’s ISAR was that the design of the plant is in general conformity with the applied requirements, the Bulgarian regulation and the international practice.No substantial design flaws have been identified and no major issues are found as missing. However, the ISAR should be significantly improved before issuing the construction permit. RISKAUDIT asked for elaboration of a revised version of the ISAR, in which all the recommendations, the requests for information as well the questions should be comprehensively addressed, and explicitly referenced to facilitate their assessment. The satisfactory accomplishment of this duty has been considered. The considered as a as prerequisite for the issuance of the construction permit, 2.The REV 2 of the ISAR have been issued at the beginning of this year, BNRA and RISKAUDIT signed on a new collaboration under the above-mentioned Contract, which has the following main objectives:a. Assessing the implementation of the above-mentioned recommendations, b.Verifying and integrating the answers provided to the questions,c.Performing additional in-depth analysis aimed at completing and finalizing the previous investigations as well as addressing some complementary relevant safety issues.3.The inception meeting of this Contract is planed June 17 –18 in Sofia. Details on the planning have to be defined, but, tentatively, the assessment activity should be completed by the end of current year and the accompanying in-depth analysis at the latest at the beginnings of 2011. 4.4.The issuance of those Reports is an important technical support., The support to to the process for granting the construction permit

  4. Superresolution radar imaging based on fast inverse-free sparse Bayesian learning for multiple measurement vectors

    He, Xingyu; Tong, Ningning; Hu, Xiaowei

    2018-01-01

    Compressive sensing has been successfully applied to inverse synthetic aperture radar (ISAR) imaging of moving targets. By exploiting the block sparse structure of the target image, sparse solution for multiple measurement vectors (MMV) can be applied in ISAR imaging and a substantial performance improvement can be achieved. As an effective sparse recovery method, sparse Bayesian learning (SBL) for MMV involves a matrix inverse at each iteration. Its associated computational complexity grows significantly with the problem size. To address this problem, we develop a fast inverse-free (IF) SBL method for MMV. A relaxed evidence lower bound (ELBO), which is computationally more amiable than the traditional ELBO used by SBL, is obtained by invoking fundamental property for smooth functions. A variational expectation-maximization scheme is then employed to maximize the relaxed ELBO, and a computationally efficient IF-MSBL algorithm is proposed. Numerical results based on simulated and real data show that the proposed method can reconstruct row sparse signal accurately and obtain clear superresolution ISAR images. Moreover, the running time and computational complexity are reduced to a great extent compared with traditional SBL methods.

  5. Comparing data of terrestrial LiDAR and UAV (photogrammetric) in the context of the project "SedAlp"

    Abel, Judith; Wegner, Kerstin; Haas, Florian; Heckmann, Tobias; Becht, Michael

    2014-05-01

    The project "SedAlp" (Sediment management in Alpine basins: integrating sediment continuum, risk mitigation and hydropower) concentrates on problems and approaches related to sediment transfer in the alpine region and is embedded in the European transnational cooperation program "Alpine Space". The catholic University Eichstätt-Ingolstadt contributes the German part to this project on behalf of the Bavarian Environment Agency and in collaboration with the Authority of Water Resources Weilheim. The area of interest is the river Isar between the Sylvenstein reservoir and the city of Bad Tölz, Bavaria, Germany. The main aim of the activities is to quantify the transfer of sediments from the tributary catchments to the river Isar, specifically in light of the fact that the construction of the Sylvenstein reservoir in the mid 1950ies has created a barrier to longitudinal sediment transfer, thus heavily impacting the sediment budget and morphodynamics of the Isar reaches downstream. Moreover, the further development of artificially inserted gravel deposits and the effect of dismantling reinforcement structures at the river banks need investigation. Therefore, the dynamics of alluvial fans and gravel bars in the areas of confluence of tributary torrents are monitored using multitemporal surveys with terrestrial laserscanners and drone-based imagery. The latter is used both for the generation of high-resolution digital elevation models and for the mapping of changes in comparison to historical aerial photos. This study focuses on a comparison of TLS and UAV-based photogrammetric digital elevation models in order to highlight advantages and disadvantages of the two methods in relation to the SedAlp-specific research problems. It is shown that UAV-based elevation models are highly accurate alternatives to TLS-based models; due to their favourable acquisition geometry with respect to the topography in floodplain areas, and their large areal coverage, their use is seen as

  6. AVARIS - AREVA Valve Repair in-Situ. Innovative technology and processes

    Schultz, Ch.

    2012-01-01

    Concept of in-situ welding and turning machine is explained. The AVARIS processes are: Disassembly Evaluation Turning Welding Finish turning Penetration test Grinding Reassembly Result - The seats are within the dimensional and hardness tolerances. The repaired valves with AVARIS as in the case of Isar 2 in 2010 did not show any indications after one year in operation Advantages: Development based on an approved and safe technology; Capability for improving and/or modification of the hardfacing material according to specific system conditions; Minimization of dose exposure (ALARA)

  7. Doubts about hybrids

    Anon.

    1982-01-01

    The natural draught wet cooling tower with a height of 160 m is considerably taller than the 80 m high hybrid cooling tower, but the latter has a considerably larger diameter. Spray losses for both types are about 4.5 kg/sec for a thermal output of 2500 MW. Apart from the pump load, the natural cooling tower requires no power. Apart from higher pump loads, the hybrid cooling tower requires power for the fans. The energy demand for this purpose is 1.5 to 3% of the nett powerstation output. For the Isar 2 nuclear powerstation this would mean a reduction in puput of about 35 MW. (orig.) [de

  8. Beyond the apparent banality of the mathematics classroom

    Laborde, Colette; Sierpinska, Anna

    2005-01-01

    The book presents nine research works within the chosen theme and focus in a coherent theoretical perspective. The other two are commentary papers offering a reflection on studies of classroom situations from the point of view of other theoretical viewpointsFor the time being, only a small number of publications on this topic (and with this approach isare available in English. Taking classroom situation and teacher's work as central often gives rise to long term studies. A book offering results coming from such studies could be valuable for the community of researchers and mathematics educators.

  9. A field- and laboratory-based quantitative analysis of alluvium: Relating analytical results to TIMS data

    Wenrich, Melissa L.; Hamilton, Victoria E.; Christensen, Philip R.

    1995-01-01

    Thermal Infrared Multispectral Scanner (TIMS) data were acquired over the McDowell Mountains northeast of Scottsdale, Arizona during August 1994. The raw data were processed to emphasize lithologic differences using a decorrelation stretch and assigning bands 5, 3, and 1 to red, green, and blue, respectively. Processed data of alluvium flanking the mountains exhibit moderate color variation. The objective of this study was to determine, using a quantitative approach, what environmental variable(s), in the absence of bedrock, is/are responsible for influencing the spectral properties of the desert alluvial surface.

  10. Remote sensing for oil spill detection and response

    Engelhardt, F.R.

    1999-01-01

    This paper focuses on the use of remote sensing for marine oil spill detection and response. The surveillance and monitoring of discharges, and the main elements of effective surveillance are discussed. Tactical emergency response and the requirements for selecting a suitable remote sensing approach, airborne remote sensing systems, and the integration of satellite and airborne imaging are examined. Specifications of satellite surveillance systems potentially usable for oil spill detection, and specifications of airborne remote sensing systems suitable for oil spill detection, monitoring and supplemental actions are tabulated, and a schema of integrated satellite-airborne remote sensing (ISARS) is presented. (UK)

  11. PPP in Denmark

    Kristiansen, Kristian

    2009-01-01

    It is the aim of the paper to contribute to the discussion on restating the PPP principles. The paper is based on an ongoing research project: ”Procuring Facilities Management through PPP´s”. A review of litterature with a critical, but positive attitude towards PPP is given. An overview of PPP...... in Denmark is presented. Only a few PPP´s have been initiated and though more might be in the pipeline, it is likely that the market for PPP is too small. Government policy is positive toward PPP. Private financing is not seen as an essential part of PPP. Attitudes among participants in PPP isare described...

  12. Theatre of Presence - Antero Alli's Paratheatrical ReSearch Lab

    Isar, Nicoletta

    the oppression, decadence and corruption that has crucified and buried the poetic Imagination" (Antero Alli) This paper will try to unveil one of Antero Alli's paratheatrical experiments in overcoming the death of ritual in theatre. Orphans of Delirium is an intense, living ritual experience, "fluid" in its...... do not repeat ritual patterns but create them, bringing shots of presence into theatre by a dynamic and constant process of opening toward the vertical "sources." Nicoletta Isar is Associate professor at the Institute of Art History of Copenhagen University. Her main research is focused...

  13. Editorial - Special Issue on the Ninth International Conference on Aeolian Research - ICAR IX (Coastal Dune Processes and Aeolian Transport)

    da Silva, Graziela Miot

    2018-04-01

    This special issue combines some of the papers related to coastal dune processes and aeolian sediment transport that were presented at the Ninth International Conference on Aeolian Research - ICAR IX. The conference was held between 4 and 8 of July 2016 in Mildura, Australia, organized by the International Society for Aeolian Research (ISAR) and convened by Adrian Chappell (Cardiff University), Craig Strong (Australian National University), Stephen Cattle (University of Sydney), Patrick Hesp (Flinders University), John Leys (New South Wales Office of Environment and Heritage), Lynda Petherick (University of Wellington) and Nick Webb (USDA-ARS Jornada Experimental Range).

  14. Quadratic Frequency Modulation Signals Parameter Estimation Based on Two-Dimensional Product Modified Parameterized Chirp Rate-Quadratic Chirp Rate Distribution.

    Qu, Zhiyu; Qu, Fuxin; Hou, Changbo; Jing, Fulong

    2018-05-19

    In an inverse synthetic aperture radar (ISAR) imaging system for targets with complex motion, the azimuth echo signals of the target are always modeled as multicomponent quadratic frequency modulation (QFM) signals. The chirp rate (CR) and quadratic chirp rate (QCR) estimation of QFM signals is very important to solve the ISAR image defocus problem. For multicomponent QFM (multi-QFM) signals, the conventional QR and QCR estimation algorithms suffer from the cross-term and poor anti-noise ability. This paper proposes a novel estimation algorithm called a two-dimensional product modified parameterized chirp rate-quadratic chirp rate distribution (2D-PMPCRD) for QFM signals parameter estimation. The 2D-PMPCRD employs a multi-scale parametric symmetric self-correlation function and modified nonuniform fast Fourier transform-Fast Fourier transform to transform the signals into the chirp rate-quadratic chirp rate (CR-QCR) domains. It can greatly suppress the cross-terms while strengthening the auto-terms by multiplying different CR-QCR domains with different scale factors. Compared with high order ambiguity function-integrated cubic phase function and modified Lv's distribution, the simulation results verify that the 2D-PMPCRD acquires higher anti-noise performance and obtains better cross-terms suppression performance for multi-QFM signals with reasonable computation cost.

  15. Angular glint effects generation for false naval target verisimility requirements

    Kostis, Theodoros G; Galanis, Konstantinos G; Katsikas, Sokratis K

    2009-01-01

    A stimulating problem in the generation of coherent countermeasures for high range resolution radar systems is the inclusion of angular glint effects in the preparation of the false target mask. Since angular glint is representative of extended naval targets, this inclusion increases the credibility factor of the decoy playback signal at the adversary radar-operator station. In this paper, the ability of an interferometric inverse synthetic aperture radar (InISAR) simulator to provide a proof of concept towards the clarification of this challenging task is ascertained. The solution consists of three novel vector representations of the generated data, which are proven to behave according to the laws of physics governing the glint phenomenon. The first depiction is the angular glint injection at the target which is followed by the representation of the wavefront distortion at the radar. A value-added time procession integration of the target in pure roll motion provides an expected by ISAR theory side-view image of the naval extended false target. The effectiveness of the proposed approach through verification and validation of the results by using the method of pictorial evidence is established. A final argument is raised on the usage of this software tool for actual obfuscation and deception actions for air defence at sea applications

  16. High resolution through-the-wall radar image based on beamspace eigenstructure subspace methods

    Yoon, Yeo-Sun; Amin, Moeness G.

    2008-04-01

    Through-the-wall imaging (TWI) is a challenging problem, even if the wall parameters and characteristics are known to the system operator. Proper target classification and correct imaging interpretation require the application of high resolution techniques using limited array size. In inverse synthetic aperture radar (ISAR), signal subspace methods such as Multiple Signal Classification (MUSIC) are used to obtain high resolution imaging. In this paper, we adopt signal subspace methods and apply them to the 2-D spectrum obtained from the delay-andsum beamforming image. This is in contrast to ISAR, where raw data, in frequency and angle, is directly used to form the estimate of the covariance matrix and array response vector. Using beams rather than raw data has two main advantages, namely, it improves the signal-to-noise ratio (SNR) and can correctly image typical indoor extended targets, such as tables and cabinets, as well as point targets. The paper presents both simulated and experimental results using synthesized and real data. It compares the performance of beam-space MUSIC and Capon beamformer. The experimental data is collected at the test facility in the Radar Imaging Laboratory, Villanova University.

  17. Mechanized radiation testing of austenitic pipe welds. Testing of media filled pipes and determination of the flaw depth by tomosynthesis; Mechanisierte Durchstrahlungspruefung von Rundschweissnaehten. Pruefung mediengefuellter Rohrleitungen und Tiefenlagenbestimmung durch Tomosynthese

    Ewert, U.; Redmer, B. [Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin (Germany); Mueller, J. [COMPRA GmbH, Frechen (Germany); Trobitz, M. [Kernkraftwerke Gundremmingen Betriebsgesellschaft mbH, Gundremmingen (Germany); Baranov, V.A. [Institute for Introscopy, Tomsk (Russian Federation)

    1999-08-01

    A compact detection system was built for multi-angle inspection of pipes, consisting of a high-sensitivity radiometric line scanner and an ultrasonic manipulator. Improved flaw imaging quality is achieved with this system as compared to film radiography. Measurements have been carried out on site in a nuclear power plant and in a laboratory. Better flaw imaging quality was also achieved in the testing of water-filled pipes. Non-linear tomosynthesis was applied for processing and interpretation of measured data. The system delivers considerably better images of planary materials inhomogeneitites, (such as cracks and lack-of-bond defects). (orig./CB) [Deutsch] Eine hoch empfindliche radiometrische Zeilenkamera wurde mit einem Ultraschall-Manipulator zu einem Gesamtsystem aufgebaut und fuer Mehrwinkel-Inspektionen von Rohrleitungen angewandt. Bei der Inspektion von Rundschweissnaehten an Rohren mit ca. 8... 20 mm Wanddicke wurde eine Verbesserung der Bildqualitaet im Vergleich zur Filmradiographie erreicht. Diese Messungen wurden in einem Kernkraftwerk unter Vor-Ort-Bedingungen sowie im Labor ausgefuehrt. Ein signifikantes Ansteigen der Bildqualitaet wurde auch bei der Pruefung von wassergefuellten Rohren erzielt. Methoden der nicht-linearen Tomosynthese wurden fuer die Verarbeitung und Interpretation der gemessenen Projektionsdaten genutzt. Das entwickelte System gestattet eine erhebliche Verbesserung der Anzeige von planaren Materialinhomogenitaeten (z.B. Risse und Bindefehler). (orig./DGE)

  18. Compact sodium cooled nuclear power plant with fast core (KNK II- Karlsruhe), Safety Report

    1977-09-01

    After the operation of the KNK plant with a thermal core (KNK I), the installation of a fast core (KNK II) had been realized. The planning of the core and the necessary reconstruction work was done by INTERATOM. Owner and customer was the Nuclear Research Center Karlsruhe (KfK), while the operating company was the Kernkraftwerk-Betriebsgesellschaft mbH (KBG) Karlsruhe. The main goals of the KNK II project and its special experimental test program were to gather experience for the construction, the licensing and operation of future larger plants, to develop and to test fuel and absorber assemblies and to further develop the sodium technology and the associated components. The present safety report consists of three parts. Part 1 contains the description of the nuclear plant. Hereby, the reactor and its components, the handling facilities, the instrumentation with the plant protection, the design of the plant including the reactor core and the nominal operation processes are described. Part 2 contains the safety related investigation and measures. This concerns the reactivity accidents, local cooling perturbations, radiological consequences with the surveillance measures and the justification of the choice of structural materials. Part three finally is the appendix with the figures, showing the different buildings, the reactor and its components, the heat transfer systems and the different auxiliary facilities [de

  19. Practical event analysis; Durchfuehrung von Ereignisanalysen in der Praxis

    Scheuring, R. [Bayernwerk Kernenergie GmbH - Kernkraftwerk Grafenrheinfeld (Germany)

    1999-04-01

    The paper explains the systematic approaches and practical aspects of evaluation of NPP operating reports and implementation of identified remedial action for enhancing the safety in terms of human, organisational, and technology factors. The procedures adopted for the Grafenrheinfeld nuclear power station (KKG) serve as an example. (orig./CB) [German] Ein wichtiger Bestandteil zur Erhaltung und Fortentwicklung des Sicherheitsniveaus ist das Lernen aus der Erfahrung. Hierzu wiederum ist ein systematisches Vorgehen zur Vermeidung von Fehlern und Behebung von Schwachstellen menschlicher, technischer und organisatorischer Natur unabdingbare Voraussetzung. Die Anwendung einer umfassenden Auswertemethodik beinhaltet - die Erfassung und Informationsweitergabe externer und interner Vorkommnisse und Erfahrungen - eine systematische Analyse/Auswertung - eine konsequente Umsetzung der Abhilfemassnahmen unter Einbeziehen aller betroffenen Organisationseinheiten. Wie erfolgt die Umsetzung dieser Vorgaben in die Praxis? Im Kernkraftwerk Grafenrheinfeld (KKG) ist die Auswertung von externen und internen Betriebserfahrungen als Aufgabe im Betriebshandbuch (BHB) 'Personelle Betriebsorganisation' vorgegeben und im Detail im Sinne der Ablauforganisation im Qualitaetssicherungshandbuch in Qualitaetssicherungsanweisungen (QSA) beschrieben. (orig.)

  20. Comparison calculation/experiment on the load case ``shutdown of TH high pressure pumps under consideration of fluid structure interaction``; Vergleich Rechnung/Messung zum Lastfall ``Abschaltung der TH-Hochdruckpumpen unter Beruecksichtigung der Fluid-Struktur-Wechselwirkung``

    Erath, W.; Nowotny, B.; Maetz, J. [KED, Rodenbach (Germany)

    1998-11-01

    Measurements of an experiment in a pipe system with pump shutdown and valve closing have been performed in the nuclear power plant KRB II. Comparative calculations of fluid and structure including interaction show an excellent agreement with the measured results. Theory and implementation of the fluid/structure interaction and the results of the comparison are described. It turns out that the consideration of the fluid/structure interaction is mostly a significant increase of the effective structural damping. (orig.) [Deutsch] Es wurden Messungen am nuklearen Nachkuehlsystem des Kernkraftwerks Gundremmingen (KRB II) bei einem Versuche mit Pumpenabschalten und Ventilschliessen durchgefuehrt. Vergleichsrechnungen der Fluid-Strukturdynamik unter echter Beruecksichtigung der Wechselwirkung ergaben eine ausgezeichnete Uebereinstimmung der Rechnung mit den Messungen. Es werden Theorie und Implementierung der Koppelung der Fluid- und Struktur-Berechnungen sowie die Vergleiche von Messung und Rechnung beschrieben. Es ergibt sich, dass die Beruecksichtigung der Wechselwirkung notwendig ist zur genaueren Berechnung von `weichen` Rohrleitungsystemen. Eine wichtige Folge der Wechselwirkung ist meist eine deutliche Erhoehung der effektiven Strukturdaempfung. (orig.)

  1. High-resolution gamma spectroscopy with whole-body and partial-body counters. Experience, recommendations. Report; Hochaufloesende Gamma-Spektrometrie an Ganz- und Teilkoerperzaehlern. Erfahrungen, Empfehlungen. Bericht

    Sahre, P. [comp.

    1997-12-01

    The application of high-resolution gamma spectroscopy with whole-body and partial-body counters shows a steadily rising upward trend over the last few years. This induced the ``Arbeitskreis Inkorporationsueberwachung`` of the association ``Fachverband fuer Strahlenschutz e.V.`` to organise a meeting for joint elaboration of a guide on recommended applications of this measuring technique, based on a review of existing experience and results. A key item on the agenda of the meeting was the comparative evaluation of the Ge semiconductor detector and the NaI solid scintillation detector. (orig./CB) [Deutsch] Der Einsatz der hochaufloesenden Gammaspektroskopie in Ganz- und Teilkoerperzaehlern hat in den letzten Jahren stetig zugenommen. Der ``Arbeitskreis Inkorporationsueberwachung`` des Fachverbandes fuer Strahlenschutz e.V. hat darum bisherige Erfahrungen zusammengetragen und Empfehlungen fuer den Einsatz dieser Messtechnik erarbeitet. Der Schwerpunkt der Tagung lag beim Vergleich von Germaniumhalbleiter- mit Natriumjodid-Festszintillationsdetektoren.Tl-Detektoren eignen sich v.a. beim Vorhandensein bekannter und zeitlich konstanter Nuklidvektoren (Kernkraftwerke, Nuklearmedizin). Bei unbekanntem bzw. variablem Nuklidvektor (Stoerfall, Unfall, Forschung) sollen Ge-Detektoren benutzt werden (orig./ABI)

  2. The EPR (European Pressurized Water Reactor) containment - concept, testing of leakage behaviour, FRP liner

    Touret, J.P. [EDF SEPTEN, Villeurbanne (France); Liersch, G. [Bayernwerk Kerenergie GmbH, Muenchen (Germany); Danisch, R. [Siemens AG, KWU NAD, Erlangen (Germany)

    2001-07-01

    The Basic Design of the EPR has now been completed. The containment plays a major safety-related role with respect to protection of the environment against radioactive releases. The EPR features a double (steel-reinforced concrete/prestressed concrete) containment design, with the inner containment coated additionally with a fibreglass-reinforced plastic (FRP) liner in certain areas. This means that containment leaktightness is provided mainly by the prestressed concrete and the FRP liner in the event of a postulated accident. The numerous findings of the tests carried out so far in both France and Germany are summarized. (orig.) [German] Das Basic Design fuer den EPR ist fertiggestellt. Entscheidend fuer eine Realisierung wird neben der politischen Akzeptanz vor allem die Wettbewerbsfaehigkeit mit anderen Energietraegern sein. Im EPR-Projekt wird der hohe Sicherheitsstandard der heutigen Kernkraftwerke in Deutschland und Frankreich ergaenzt, indem zusaetzlich technische Massnahmen ergriffen werden, um die Konsequenzen beim unterstellten Versagen aller sicherheitstechnischen Einrichtungen mit der Folge eines postulierten Niederschmelzen des Kerns technisch zu beherrschen. (orig.)

  3. Risk reduction category (RRC-A) accident studies in the safety analysis report of the EPR trademark reactor

    Poehlmann, M.; Bleher, G.; Ismaier, A.; Knoll, A.; Levi, P.; Garcia, E. Vera; Schels, A.; Seitz, H.; Lima Campos, L.

    2013-01-01

    The Risk Reduction Category (RRC-A) is considered in the safety demonstration of nuclear reactors in addition to design basis operating conditions (Plant Condition Category, PCC), in order to analyze with a risk reduction approach any operating conditions with multiple failures. As extending the operating conditions of the plant 'beyond design basis', the Risk Reduction Category (RRC-A) is also denoted as Design Extension Condition (DEC-A). In the German licensing framework, the RRCA (or DEC-A) transients correspond to safety assessment level '4b' of the 'Sicherheitsanforderungen an Kernkraftwerke' (Safety Requirements for Nuclear Power Plants), Az. RS I 5 - 13303/01 of the German Federal Ministry for the Environment, Nature Conservation and Nuclear Safety. These RRC-A (or DEC-A) operating conditions require specific design provisions (implemented by manual or automatic action), known as RRC-A measures, intended to render consequences of accumulated failures admissible. In contrast, RRC-B constitute severe accidents that lead to core melt. Identification of RRC-A operating conditions and corresponding RRC-A measures is based on the use of results of probabilistic safety assessments. After the Fukushima accident the RRC-A accidents like Station Black Out (SBO) or Loss of Ultimate Heat Sink (LUHS) are of particular interest in the safety assessment of nuclear new builds. In several chapters of the Safety Analysis Report it is demonstrated that the AREVA EPRTM design is resistant at RRC-A accident conditions. (orig.)

  4. Nuclear power: Hour of fog producers; Atomkraft: Stunde der Nebelwerfer

    Rauner, M.; Schuh, H.

    2004-03-04

    Seven advanced nuclear power plants in Germany can withstand a frontal crash by a full-tanked Jumbo-Jet. But for five older plants even smaller planes can cause an hazard impossible to control. A fog generation around the power plants, favorized by operators and politicians, to camouflage this plants against terroristic flights is absurd because of the possibility of flight automation. However terrorists may attack reactors also from the ground, but how they can do is top secret. (GL) [German] Einem frontalen Aufprall eines voll getankten Jumbo-Jets mit hoher Geschwindigkeit koennen in Deutschland sieben moderne Kernkraftwerke standhalten. Bei fuenf aelteren Modellen kann dagegen selbst ein kleineres Flugzeug ein schwer beherrschbares Unglueck ausloesen. Obwohl Experten eine vorzeitige Schliessung solch alter Meiler fuer realistisch halten, ist die Verhandlungslage aufgrund ideologischer Einfluesse verfahren. Die von Betreibern und Politikern gern gepriesenen Nebelwerfer zur Tarnung der Kraftwerke sind wegen der Moeglichkeit des Instrumentenfluges sinnlos. Die beste Abwehr bieten vorgelagerte Schutzbauten aus Beton. Jedoch koennen Terroristen Reaktoren auch vom Boden aus gefaehrden, wie, ist natuerlich geheim.

  5. Commentary on: "Randomized, controlled, double-blind, cross-over trial assessing treatment preference for pazopanib versus sunitinib in patients with metastatic renal cell carcinoma: PISCES study." Escudier B, Porta C, Bono P, Powles T, Eisen T, Sternberg CN, Gschwend JE, De Giorgi U, Parikh O, Hawkins R, Sevin E, Négrier S, Khan S, Diaz J, Redhu S, Mehmud F, Cella D. Bernard Escudier, Institut Gustave Roussy, Villejuif; Emmanuel Sevin, Centre François Baclesse, Caen; Sylvie Négrier, Leon Berard Cancer Center, Lyon, France; Camillo Porta, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico S. Matteo, Pavia; Cora N Sternberg, San Camillo Forlanini Hospital, Rome; Ugo De Giorgi, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Italy; Petri Bono, Helsinki University Central Hospital, Helsinki, Finland; Thomas Powles, Barts Experimental Cancer Medicine Centre, Barts Cancer Institute, Queen Mary University of London, London; Tim Eisen, Cambridge University Health Partners, Cambridge; Omi Parikh, Royal Preston Hospital, Lancashire; Robert Hawkins, Christie Cancer Research UK, Manchester; Sadya Khan, Jose Diaz, and Faisal Mehmud, GlaxoSmithKline, Uxbridge, United Kingdom; Jürgen E Gschwend, Klinikum Rechts der Isar der Technischen Universität München, Munich, Germany; Suman Redhu, GlaxoSmithKline, Collegeville, PA; David Cella, Northwestern University Feinberg School of Medicine, Chicago, IL.: J Clin Oncol. 2014 May 10;32(14):1412-1418; doi: 10.1200/JCO.2013.50.8267. [Epub 2014 Mar 31].

    Trump, Donald

    2016-05-01

    Patient-reported outcomes may help inform treatment choice in advanced/metastatic renal cell carcinoma (RCC), particularly between approved targeted therapies with similar efficacy. This double-blind crossover study evaluated patient preference for pazopanib or sunitinib and the influence of health-related quality of life (HRQoL) and safety factors on their stated preference. Patients with metastatic renal cell carcinoma were randomly assigned to pazopanib 800mg per day for 10 weeks, a 2-week washout, and then sunitinib 50mg per day (4 weeks on, 2 weeks off, 4weeks on) for 10 weeks, or the reverse sequence. The primary end point, patient preference for a specific treatment, was assessed by questionnaire at the end of the two treatment periods. Other end points and analyses included reasons for preference, physician preference, safety, and HRQoL. Of 169 randomly assigned patients, 114 met the following prespecified modified intent-to-treat criteria for the primary analysis: exposure to both treatments, no disease progression before cross over, and completion of the preference questionnaire. Significantly more patients preferred pazopanib (70%) over sunitinib (22%); 8% expressed no preference (P<.001). All preplanned sensitivity analyses, including the intent-to-treat population, statistically favored pazopanib. Less fatigue and better overall quality of life were the main reasons for preferring pazopanib, with less diarrhea being the most cited reason for preferring sunitinib. Physicians also preferred pazopanib (61%) over sunitinib (22%); 17% expressed no preference. Adverse events were consistent with each drug׳s known profile. Pazopanib was superior to sunitinib in HRQoL measures evaluating fatigue, hand/foot soreness, and mouth/throat soreness. This innovative crossover trial demonstrated a significant patient preference for pazopanib over sunitinib, with HRQoL and safety as key influencing factors. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Optical image security using Stokes polarimetry of spatially variant polarized beam

    Fatima, Areeba; Nishchal, Naveen K.

    2018-06-01

    We propose a novel security scheme that uses vector beam characterized by the spatially variant polarization distribution. A vector beam is so generated that its helical components carry tailored phases corresponding to the image/images that is/are to be encrypted. The tailoring of phase has been done by employing the modified Gerchberg-Saxton algorithm for phase retrieval. Stokes parameters for the final vector beam is evaluated and is used to construct the ciphertext and one of the keys. The advantage of the proposed scheme is that it generates real ciphertext and keys which are easier to transmit and store than complex quantities. Moreover, the known plaintext attack is not applicable to this system. As a proof-of-concept, simulation results have been presented for securing single and double gray-scale images.

  7. Unconsummated marriage in sub-Saharan Africa: case reports.

    Lema, Valentino M

    2014-09-01

    Unconsummated marriage is a condition where newly married couples are unable to achieve penile-vaginal intercourse for variable periods despite desire and several attempts to do so. Its exact cause(s) is/are unknown, but performance anxiety resulting from or leading to other conditions is reportedly the major etiological factor. It is thought to be more prevalent in traditional and conservative religious communities where premarital sexual exposure is strictly prohibited. Most publications on unconsummated marriage have originated from North America, European and Middle Eastern countries. There have not been any such reports from sub-Saharan Africa, which is home to diverse cultures and traditions regarding premarital sex and marriage. This paper presents a sample of four cases with unconsummated marriage managed by the author in his private clinic based in the city of Nairobi Kenya, over the past five years. Possible etiological factors and management approaches are discussed, with a review of relevant literature.

  8. Phantom Tumor of the Lung: Localized Interlobar Effusion in Congestive Heart Failure

    Mislav Lozo

    2014-01-01

    Full Text Available Localized interlobar effusions in congestive heart failure (phantom or vanishing lung tumor/s is/are uncommon but well known entities. An 83-year-old man presented with shortness of breath, swollen legs, and dry cough enduring five days. Chest-X-ray (CXR revealed massive sharply demarked round/oval homogeneous dense shadow 10 × 7 cm in size in the right inferior lobe. The treatment with the loop diuretics and fluid intake reduction resulted in complete resolution of the observed round/oval tumor-like image on the control CXR three days later. Radiologic appearance of such a mass-like configuration in patients with congestive heart failure demands correction of the underlying heart condition before further diagnostic investigation is performed to avoid unnecessary, expensive, and possibly harmful diagnostic and treatment errors.

  9. On results using automated wideband instrumentation for radar measurements and characterization

    Govoni, Mark A.; Dogaru, Traian; Le, Calvin; Sobczak, Kevin

    2017-05-01

    Experiences are shared from a recent radar measurement and characterization effort. A regimented data collection procedure ensures repeatability and provides an expedited alternative to typical narrowband capabilities. Commercially-available instrumentation is repurposed to support wideband data collections spanning a contiguous range of frequencies from 700 MHz to 40 GHz. Utilizing a 4-port network analyzer, both monostatic and quasi-monostatic measurements are achievable. Polarization is varied by way of a custom-designed antenna mount that allows for the mechanical reorientation of the antennas. Computational electromagnetic modeling is briefly introduced and serves in validating the legitimacy of the collection capability. Data products presented will include high-range resolution profiles and inverse synthetic aperture radar (ISAR) imagery.

  10. VICTOR HAGEA AMAZING!

    Isar, Nicoletta

    VICTOR HAGEA's "Amazing!" includes 28 amazing artworks of Victor Hagea (lives and works in Munchen /Germany) and 14 critical essays and work reviews by Nicoletta Isar ((lives and works in Copenhagen /Denmark).  Size 12¼ x 10 in / 31,5 x 25 cm,  66 color pages, hardcover and  Busines Replay Card......, quality printed in Europe. Marketing and distribution through large book wholesalers and ecommerce channels in US bookstores and eCommerce internationally including Barnes and Noble, Borders, Amazon in USA, Amazon Canada, Amazon France, Amazon Germany, Amazon UK, Amazon Australia and others. The book...... is created by Petru A. RUSSU, editor and publisher of World of Art (WOA), fine artist (lives and works in London and Stockholm)....

  11. RNA and protein synthesis of irradiated Ehrlich ascites tumour cells. Pt. 2

    Skog, S.; Tribukait, B.; Nygard, O.; Wenner-Gren-Center foer Vetenskaplig Forskning, Stockholm

    1985-01-01

    Poly(A)-containing RNA (m-RNA) was studied in in vivo growing Ehrlich ascites tumour cells following a roentgen irradiation dose of 5 Gy. m-RNA increased significantly during the first 12 hours after irradiation. Thus, the observed decrease in protein synthesis rate during this time seems not to be due to radiation induced changes at the transcriptional level. The protein synthesis rate of in vivo irradiated cells incubated in vitro in culture medium was unchanged. On the other hand, the protein synthesis rate of non-irradiated cells incubated in vitro in ascites fluid from irradiated animals was decreased. We concluded that factor(s) inhibiting protein synthesis or the lack of factor(s) promoting protein synthesis in the ascites fluid is(are) of significance for the reduced protein synthesis of tumour cells found in irradiated in vivo growing cells. (orig.)

  12. Post-infarctus, ischémie myocardique: importance clinique et facteur de risque

    Jespersen, C

    1995-01-01

    disease surviving out of hospital cardiac arrest - improves the prognosis, indicates that transient ischaemic attacks might be the trigger of malignant ventricular arrhythmias in patients with prior myocardial infarction. Patients with large infarct scars (heart failure) have an increased incidence...... and the release of abnormal automatic responses of the partially repolarised cells. The mechanism(s) by which complex ventricular arrhythmias is/are transformed into malignant arrhythmias has/have not yet been definitely proven. The observation that coronary revascularization - in patients with ischaemic heart......, indicating that residual ischaemia might be the major risk variable in patients with heart failure. Ischaemia is one of several risk markers for transient supraventricular arrhythmias in patients recovering from an acute myocardial infarction (AMI). In addition, anti-ischaemic intervention in patients...

  13. Reduction of construction periods of PWRs by optimization of detailed sequence planning

    Stocker, W.; Leverenz, R.

    1991-01-01

    The construction of PWR's is an enterprise with high investment costs, in total up to three billion US$ and with long construction periods of five years and more. Besides the results reached by the intensive standardization, a further reduction of the construction period is possible by optimization of detailed sequence planning and interfaces of work units. During the execution of the three German Convoy plants ISAR 2, EMSLAND and NECKARWESTHEIM 2, the contractual construction periods were shortened between 4 and 8 months. These reductions were reached after individual investigations by measures like advanced finishing work activities; erection of an increased amount of prefabricated pipings; rearrangement of erection sequences; overlapping of piping erection and electrical installation; reduction of plant commissioning period. All these measures support directly the reduction of the total investment cost of a plant, as already demonstrated by the Convoy plants. (author). 8 figs

  14. Implementation of an aging management concept using COMSY; Umsetzung eines Alterungsmanagementkonzeptes mit COMSY

    Ulmer, Maximilian [E.ON Kernkraft AG, Essenbach (Germany). Isar 2; Wildner, Udo; Nopper, Helmut [AREVA NP GmbH, Erlangen (Germany)

    2011-07-01

    For the systematic monitoring of physical aging processes in reactor components the German standards KTA 1403 prescribe a systematic aging management, i.e. an integrated concept for the continuous conservation of the required quality. Central point is the PDCA (plan-do-check-act) cycle that allows a systematic process-oriented monitoring of the plant status. In the NPP Isar 2 the adapted knowledge-based software package COMSY is used, that includes the evaluation of the current status of the plant, calculation tools for the determination of the relevant damage mechanisms and their consequences, an integrated module to evaluate inspection results and an integrated module to manage and evaluate incidents. Using transferability tests special test can be recommended in order to avoid common mode failures. The annual analysis includes an automatic documentation of results and evaluations.

  15. Time varying voltage combustion control and diagnostics sensor

    Chorpening, Benjamin T [Morgantown, WV; Thornton, Jimmy D [Morgantown, WV; Huckaby, E David [Morgantown, WV; Fincham, William [Fairmont, WV

    2011-04-19

    A time-varying voltage is applied to an electrode, or a pair of electrodes, of a sensor installed in a fuel nozzle disposed adjacent the combustion zone of a continuous combustion system, such as of the gas turbine engine type. The time-varying voltage induces a time-varying current in the flame which is measured and used to determine flame capacitance using AC electrical circuit analysis. Flame capacitance is used to accurately determine the position of the flame from the sensor and the fuel/air ratio. The fuel and/or air flow rate (s) is/are then adjusted to provide reduced flame instability problems such as flashback, combustion dynamics and lean blowout, as well as reduced emissions. The time-varying voltage may be an alternating voltage and the time-varying current may be an alternating current.

  16. Research on the range side lobe suppression method for modulated stepped frequency radar signals

    Liu, Yinkai; Shan, Tao; Feng, Yuan

    2018-05-01

    The magnitude of time-domain range sidelobe of modulated stepped frequency radar affects the imaging quality of inverse synthetic aperture radar (ISAR). In this paper, the cause of high sidelobe in modulated stepped frequency radar imaging is analyzed first in real environment. Then, the chaos particle swarm optimization (CPSO) is used to select the amplitude and phase compensation factors according to the minimum sidelobe criterion. Finally, the compensated one-dimensional range images are obtained. Experimental results show that the amplitude-phase compensation method based on CPSO algorithm can effectively reduce the sidelobe peak value of one-dimensional range images, which outperforms the common sidelobe suppression methods and avoids the coverage of weak scattering points by strong scattering points due to the high sidelobes.

  17. On the form of species–area relationships in habitat islands and true islands

    Matthews, Thomas J.; Guilhaumon, François; Triantis, Kostas A.

    2016-01-01

    and c vary between different island types. Location: Global. Methods: We used an information theoretic approach to compare the fit of 20 ISAR models to 207 habitat island datasets. Model performance was ranked according to pre-set criteria, including metrics of generality and efficiency. We also fitted......, and was the highest ranked model overall. In general, the more complex models performed badly. Average z-values were significantly lower for habitat island datasets than for true islands, and were higher for mountaintop and urban habitat islands than for other habitat island types. Average c-values were significantly...... multimodel comparisons demonstrated the nonlinear implementation of the power model to be the best overall model and thus to be a sensible choice for general use. As the z-value of the log–log power model varied in relation to ecological and geographical properties of the study systems, caution should...

  18. Comparison of Efficacy of Eye Movement, Desensitization and Reprocessing and Cognitive Behavioral Therapy Therapeutic Methods for Reducing Anxiety and Depression of Iranian Combatant Afflicted by Post Traumatic Stress Disorder

    Narimani, M.; Sadeghieh Ahari, S.; Rajabi, S.

    This research aims to determine efficacy of two therapeutic methods and compare them; Eye Movement, Desensitization and Reprocessing (EMDR) and Cognitive Behavioral Therapy (CBT) for reduction of anxiety and depression of Iranian combatant afflicted with Post traumatic Stress Disorder (PTSD) after imposed war. Statistical population of current study includes combatants afflicted with PTSD that were hospitalized in Isar Hospital of Ardabil province or were inhabited in Ardabil. These persons were selected through simple random sampling and were randomly located in three groups. The method was extended test method and study design was multi-group test-retest. Used tools include hospital anxiety and depression scale. This survey showed that exercise of EMDR and CBT has caused significant reduction of anxiety and depression.

  19. Micro-Doppler Signal Time-Frequency Algorithm Based on STFRFT

    Cunsuo Pang

    2016-09-01

    Full Text Available This paper proposes a time-frequency algorithm based on short-time fractional order Fourier transformation (STFRFT for identification of a complicated movement targets. This algorithm, consisting of a STFRFT order-changing and quick selection method, is effective in reducing the computation load. A multi-order STFRFT time-frequency algorithm is also developed that makes use of the time-frequency feature of each micro-Doppler component signal. This algorithm improves the estimation accuracy of time-frequency curve fitting through multi-order matching. Finally, experiment data were used to demonstrate STFRFT’s performance in micro-Doppler time-frequency analysis. The results validated the higher estimate accuracy of the proposed algorithm. It may be applied to an LFM (Linear frequency modulated pulse radar, SAR (Synthetic aperture radar, or ISAR (Inverse synthetic aperture radar, for improving the probability of target recognition.

  20. Micro-Doppler Signal Time-Frequency Algorithm Based on STFRFT.

    Pang, Cunsuo; Han, Yan; Hou, Huiling; Liu, Shengheng; Zhang, Nan

    2016-09-24

    This paper proposes a time-frequency algorithm based on short-time fractional order Fourier transformation (STFRFT) for identification of a complicated movement targets. This algorithm, consisting of a STFRFT order-changing and quick selection method, is effective in reducing the computation load. A multi-order STFRFT time-frequency algorithm is also developed that makes use of the time-frequency feature of each micro-Doppler component signal. This algorithm improves the estimation accuracy of time-frequency curve fitting through multi-order matching. Finally, experiment data were used to demonstrate STFRFT's performance in micro-Doppler time-frequency analysis. The results validated the higher estimate accuracy of the proposed algorithm. It may be applied to an LFM (Linear frequency modulated) pulse radar, SAR (Synthetic aperture radar), or ISAR (Inverse synthetic aperture radar), for improving the probability of target recognition.

  1. Patient-reported outcome measures in arthroplasty registries

    Rolfson, Ola; Bohm, Eric; Franklin, Patricia

    2016-01-01

    The International Society of Arthroplasty Registries (ISAR) Patient-Reported Outcome Measures (PROMs) Working Group have evaluated and recommended best practices in the selection, administration, and interpretation of PROMs for hip and knee arthroplasty registries. The 2 generic PROMs in common use...... are the Short Form health surveys (SF-36 or SF-12) and EuroQol 5-dimension (EQ-5D). The Working Group recommends that registries should choose specific PROMs that have been appropriately developed with good measurement properties for arthroplasty patients. The Working Group recommend the use of a 1-item pain...... should consider the absolute level of pain, function, and general health status as well as improvement, missing data, approaches to analysis and case-mix adjustment, minimal clinically important difference, and minimal detectable change. The Working Group recommends data collection immediately before...

  2. A control system for and a method of controlling a superconductive rotating electrical machine

    2014-01-01

    This invention relates to a method of controlling and a control system (100) for a superconductive rotating electric machine (200) comprising at least one superconductive winding (102; 103), where the control system (100) is adapted to control a power unit (101) supplying during use the at least...... or more actual values (110, 111)of one or more parameters for a given superconductive winding (102; 103), each parameter representing a physical condition of the given superconductive winding (102; 103), and to dynamically derive one or more electrical current values to be maintained in the given...... superconductive winding (102; 103) by the power unit (101) where the one or more electrical current values is/are derived taking into account the received one or more actual values (110, 111). In this way,greater flexibility and more precise control of the performance of the superconducting rotating electrical...

  3. An advanced configuration management system for full scope power plant simulators

    Storm, J.; Goemann, A.

    1996-01-01

    In August 1993 KSG Kraftwerks-Simulator-Gesellschaft, Germany, awarded a contract to STN ATLAS Elektronik for the delivery of two full scope replica training simulators for the German BWR plants Isar 1 and Philipsburg 1, known as the double simulator project S30 (S31/S32). For both projects a computer based Configuration Management System (CMS) was required to overcome deficiencies of older simulator systems in terms of limited upgrade and maintenance capabilities and incomplete documentation. The CMS allows complete control over the entire simulator system covering all software- and hardware-items and therewith exceed quality assurance requirements as defined in ISO 9000-3 which gives recommendations for software configuration management only. The system is realized under the project using the UNIX based relational database system EMPRESS and is in use as a development- and maintenance-tool to improve simulator quality and ensure simulator configuration integrity

  4. Safety parameter display system functions are integrated parts of the KWU KONVOI process information system (SPDS functions are parts of the KWU-PRINS)

    Aleite, W.; Geyer, K.H.

    1984-01-01

    The desirability of having flexible overview as well as extended detail information with pictorial and abstraction features and easy and quick access throughout the large-size control rooms in German plants has been recognized. Developments over the last years now make it possible to add on extensive computer driven VDU-systems to the three German KONVOI NPPs (Isar II, Emsland and Neckarwestheim II) thereby creating the Process Information System ''PRINS''. The new system is driven by multiple computers at different locations controlling about 30 full-graphic, high resolution Video Display Units. They are arranged singly and in three ''mxn - Information Panels'' distributed about the control room and present all thinkable kinds of display formats with more than 1000 separate pictures. The display of only single ''Safety Parameters'' or even complete ''Safety Goal Information'' on single or multiple VDUs in parallel is only one aspect of this computerized part of the entire integrated Information System. (orig./HP)

  5. Der Stellenwert des Lebenszyklus für das Überleben der uferbewohnenden Wolfspinnenarten Pardosa wagleri (Hahn, 1822 und Pirata knorri (Scopoli, 1763

    Manderbach, Randolf

    2001-04-01

    Full Text Available Quantitative, time-limited samplings in monthly intervals from June 1995 to August 1996, in combination with the measurement of carapace width of juvenile and adult spiders has revealed the life cycle patterns of the riparian wolf spiders Pardosa wagleri and Pirata knorri and showed the effect of floods on their abundance at the Isar River (Germany, Bavaria. Adults and juvenile spiders are heavily affected by floods but the populations of both species are able to recover quickly. The life cycles of both species are synchronized with the season and display a spring/summer stenochrony. P. wagleri shows a second reproductive phase in early summer. This reproductive behaviour supports the persistence of populations in this disturbed environment.

  6. Wildfire monitoring via the integration of remote sensing with innovative information technologies

    Kontoes, C.; Papoutsis, I.; Michail, D.; Herekakis, Th.; Koubarakis, M.; Kyzirakos, K.; Karpathiotakis, M.; Nikolaou, C.; Sioutis, M.; Garbis, G.; Vassos, S.; Keramitsoglou, I.; Kersten, M.; Manegold, S.; Pirk, H.

    2012-04-01

    In the Institute for Space Applications and Remote Sensing of the National Observatory of Athens (ISARS/NOA) volumes of Earth Observation images of different spectral and spatial resolutions are being processed on a systematic basis to derive thematic products that cover a wide spectrum of applications during and after wildfire crisis, from fire detection and fire-front propagation monitoring, to damage assessment in the inflicted areas. The processed satellite imagery is combined with auxiliary geo-information layers, including land use/land cover, administrative boundaries, road and rail network, points of interest, and meteorological data to generate and validate added-value fire-related products. The service portfolio has become available to institutional End Users with a mandate to act on natural disasters and that have activated Emergency Support Services at a European level in the framework of the operational GMES projects SAFER and LinkER. Towards the goal of delivering integrated services for fire monitoring and management, ISARS/NOA employs observational capacities which include the operation of MSG/SEVIRI and NOAA/AVHRR receiving stations, NOA's in-situ monitoring networks for capturing meteorological parameters to generate weather forecasts, and datasets originating from the European Space Agency and third party satellite operators. The qualified operational activity of ISARS/NOA in the domain of wildfires management is highly enhanced by the integration of state-of-the-art Information Technologies that have become available in the framework of the TELEIOS (EC/ICT) project. TELEIOS aims at the development of fully automatic processing chains reliant on a) the effective storing and management of the large amount of EO and GIS data, b) the post-processing refinement of the fire products using semantics, and c) the creation of thematic maps and added-value services. The first objective is achieved with the use of advanced Array Database technologies, such

  7. From whole body to cellular models of hepatic triglyceride metabolism: man has got to know his limitations.

    Green, Charlotte J; Pramfalk, Camilla; Morten, Karl J; Hodson, Leanne

    2015-01-01

    The liver is a main metabolic organ in the human body and carries out a vital role in lipid metabolism. Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases, encompassing a spectrum of conditions from simple fatty liver (hepatic steatosis) through to cirrhosis. Although obesity is a known risk factor for hepatic steatosis, it remains unclear what factor(s) is/are responsible for the primary event leading to retention of intrahepatocellular fat. Studying hepatic processes and the etiology and progression of disease in vivo in humans is challenging, not least as NAFLD may take years to develop. We present here a review of experimental models and approaches that have been used to assess liver triglyceride metabolism and discuss their usefulness in helping to understand the aetiology and development of NAFLD. Copyright © 2015 the American Physiological Society.

  8. Precision Near-Field Reconstruction in the Time Domain via Minimum Entropy for Ultra-High Resolution Radar Imaging

    Jiwoong Yu

    2017-05-01

    Full Text Available Ultra-high resolution (UHR radar imaging is used to analyze the internal structure of objects and to identify and classify their shapes based on ultra-wideband (UWB signals using a vector network analyzer (VNA. However, radar-based imaging is limited by microwave propagation effects, wave scattering, and transmit power, thus the received signals are inevitably weak and noisy. To overcome this problem, the radar may be operated in the near-field. The focusing of UHR radar signals over a close distance requires precise geometry in order to accommodate the spherical waves. In this paper, a geometric estimation and compensation method that is based on the minimum entropy of radar images with sub-centimeter resolution is proposed and implemented. Inverse synthetic aperture radar (ISAR imaging is used because it is applicable to several fields, including medical- and security-related applications, and high quality images of various targets have been produced to verify the proposed method. For ISAR in the near-field, the compensation for the time delay depends on the distance from the center of rotation and the internal RF circuits and cables. Required parameters for the delay compensation algorithm that can be used to minimize the entropy of the radar images are determined so that acceptable results can be achieved. The processing speed can be enhanced by performing the calculations in the time domain without the phase values, which are removed after upsampling. For comparison, the parameters are also estimated by performing random sampling in the data set. Although the reduced data set contained only 5% of the observed angles, the parameter optimization method is shown to operate correctly.

  9. Effects of abciximab on key pattern of human coronary restenosis in vitro: impact of the SI/MPL-ratio

    Baur Regine

    2006-04-01

    Full Text Available Abstract Background The significant reduction of angiographic restenosis rates in the ISAR-SWEET study (intracoronary stenting and antithrombotic regimen: is abciximab a superior way to eliminate elevated thrombotic risk in diabetes raises the question of whether abciximab acts on clopidogrel-independent mechanisms in suppressing neointimal hyperplasia. The current study investigates the direct effect of abciximab on ICAM-1 expression, migration and proliferation. Methods ICAM-1: Part I of the study investigates in cytoflow studies the effect of abciximab (0.0002, 0.002, 0.02, 0.2, 2.0, and 20.0 μg/ml on TNF-α induced expression of intercellular adhesion molecule 1 (ICAM-1. Migration: Part II of the study explored the effect of abciximab (0.0002, 0.002, 0.02, 0.2, 2.0, and 20.0 μg/ml on migration of HCMSMC over a period of 24 h. Proliferation: Part III of the study investigated the effect of abciximab (0.0002, 0.002, 0.02, 0.2, 2.0, and 20.0 μg/ml on proliferation of HUVEC, HCAEC, and HCMSMC after an incubation period of 5 days. Results ICAM-1: In human venous endothelial cells (HUVEC, human coronary endothelial cells (HCAEC and human coronary medial smooth muscle cells (HCMSMC no inhibitory or stimulatory effect on expression of ICAM-1 was detected. Migration: After incubation of HCMSMC with abciximab in concentrations of 0.0002 – 2 μg/ml a stimulatory effect on cell migration was detected, statistical significance was achieved after incubation with 0.002 μg/ml (p 1. Conclusion Thus, the anti-restenotic effects of systemically administered abciximab reported in the ISAR-SWEET-study were not caused by a direct inhibitory effect on ICAM-1 expression, migration or proliferation.

  10. Transparency and efficiency through plant operations management systems; Transparenz und Effizienz durch Betriebsfuehrungssysteme

    Ladage, L. [RWE Power AG, Essen (Germany). Informationsmanagement

    2001-04-01

    Plant operations management systems, being IT application systems, provide integral support of the business processes making up plant operations management. The use of plant operations management systems improves mutually interdependent factors, such as high economic performance, high availability, and maximum safety. Since its commissioning in 1988, the Emsland nuclear power station (KKE) has been run with the IBFS plant operations management system. The work flow management system (WfMS), a module of IBFS, is described as an example of job order processing. IBFS-WfMS is to optimize all processes, thus cutting costs and ensuring that processes are run and documented reliably. Assessing the savings effect achieved through the use of IBFS-WfMS clearly reveals the savings in work/time achieved by the system. These savings are quoted as approx. 4 minutes and DM 10, respectively, per working step, which corresponds to several dozens of manyears or several million DM per annum in the KKE plant under consideration. This result can be extrapolated to other plants. (orig.) [German] Betriebsfuehrungssysteme stuetzen als EDV-Anwendungssystem integral die Geschaeftsprozesse der Kraftwerksbetriebsfuehrung. Durch den Einsatz von Betriebsfuehrungssystemen werden die in gegenseitiger Abhaengigkeit befindlichen Faktoren hohe Wirtschaftlichkeit, hohe Verfuegbarkeit und groesstmoegliche Sicherheit im Verbund gefoerdert. Im Kernkraftwerk Emsland (KKE) wird seit Inbetriebnahme der Anlage im Jahr 1988 das Betriebsfuehrungssystem IBFS eingesetzt. Am Beispiel des Workflowmanagementsystems (WfMS), einem Modul des IBFS, wird die Abwicklung von Arbeitsauftraegen dargestellt. Das IBFS-WfMS soll dabei durch Optimierung aller Prozesse sowohl kostensenkend wirken als auch sicherstellen, dass die Prozesse verlaesslich abgewickelt und dokumentiert werden. Eine Abschaetzung des Einspareffektes des IBFS-WfMS zeigt deutlich die durch das System erzielten Ersparnisse an Arbeits-/Zeitaufwand auf

  11. Power engineering. Systems for energy conversion. Compact knowledge for study and profession. 4. upd. and enl. ed.; Energietechnik. Systeme zur Energieumwandlung. Kompaktwissen fuer Studium und Beruf

    Zahoransky, Richard A.

    2009-07-01

    This textbook imparts to the reader a fundamental understanding for relations of energy conversion processes. It comprises the total spectra of energy engineering, starting with fundamentals of energy process engineering via description of operating power plants (all types) to energy distribution and - storage. Main topics are sustainable energy systems from renewable energy sources. combined systems (e.g. Gas/steam turbine power plants) and plants with cogeneration (e.g. modular cogeneration plants). A new chapter Kyoto-Protocol was created as a concept of emissions-free coal-fired power plants. A new wording for deregulation of energy markets was received. Numerous texts and graphs were been revised. Chapter 18 ''Deregulation of Energy Markets'' is newly revised. Due to its didactic concepts the book directs not only to students but also everybody, who is inerested into actual questions of energy engineering. (org./GL) [German] Dieses Lehrbuch vermittelt dem Leser ein grundlegendes Verstaendnis fuer die Zusammenhaenge der Energieumwandlungsprozesse. Es umfasst die gesamte Bandbreite der Energietechnik. Die Schwerpunkte reichen von nachhaltigen, erneuerbaren Energietechniken, Kombianlagen (z.B. Gas- und Dampfturbinen-Kraftwerke) ueber Anlagen mit Kraft-Waerme-Kaelte-Kopplung bis hin zum Kyoto-Protokoll. Die 4. Auflage beinhaltet erstmals Uebungsaufgaben mit ausfuehrlichen Loesungen zu den einzelnen Kapiteln. Mehrere Kapitel sind aktualisiert. Das Kapitel 18 ''Liberalisierung der Energiemaerkte'' ist neu gefasst. Aus dem Inhalt Energietechnische Grundlagen - Dampfkraftwerke - Kernkraftwerke - Gasturbinen - Kombinationskraftwerke - Stationaere Kolbenmotoren - Brennstoffzellen - Kraft-Waerme-Kaelte-Kopplung - Wasserkraft - Solartechnik - Windenergie - Biomasse - Geothermie - Energetische Muellverwertung - Energieverteilung und -speicherung - Liberalisierung der Energiemaerkte - Kyoto-Protokoll. (orig.)

  12. The year 2000 problem as seen by manufacturers; Das Jahr-2000-Problem in deutschen Kernkraftwerken. Aus der Sicht der Hersteller

    Graf, A. [Siemens AG, Erlangen (Germany). Bereich KWU

    1999-11-01

    The Y2K problem has many facets due mainly to two reasons: The extremely wide use of microcomputers, and the complexity of automation in modern industrial plants. For the past two years, Siemens AG has been checking the Y2K conformity of its products. The result of these investigations is this: All automation equipment, almost without exception, is in conformity with the year 2000 requirements as it works without the date function causing the errors. A few occasional malfunctions were discovered in older computer-supported operating and monitoring stations and in process computer applications. However, malfunctions are not going to cause failures of the system but only make its use more difficult. (orig.) [German] Ursache des Jahr-2000-Problems ist die Unfaehigkeit gewisser aelterer Software, das Jahresdatum 2000 beim Uebergang der letzten beiden Ziffern von '99' auf '00' richtig zu verarbeiten. Potenziell betroffen sind alle Geraete und Systeme, die in irgendeiner Form Rechner oder Mikrorechner enthalten. Das Jahr-2000-Problem ist sehr vielschichtig. Dies resultiert im Wesentlichen aus zwei Gruenden: Der extrem weiten Verbreitung von Mikrorechnern und der Komplexitaet der Automatisierung moderner Industrieanlagen. Die Siemens AG ueberprueft seit zwei Jahren die 2000-Jahr-Konformitaet ihrer Produkte. Ergebnis der Untersuchungen ist: Automatisierungsgeraete sind fast ausnahmslos Jahr-2000 konform, da sie ohne die fehlerverursachenden Datumsfunktionen auskommen. Vereinzelte Fehlfunktionen wurden in aelteren rechnergestuetzten Bedien- und Beobachtungssystemen sowie in Prozessrechneranwendungen gefunden. Fehlfunktionen fuehren jedoch meist nicht zum Versagen des Systems, sondern erschweren nur dessen Nutzung. In den sicherheitsrelevanten Bereichen der Kernkraftwerke werden ausschliesslich die vom Jahr-2000-Problem nicht betroffenen Automatisierungsgeraete eingesetzt. (orig.)

  13. Strategy for decommissioning of NPP's in Germany

    Rittscher, D.; Sterner, H.

    2003-01-01

    According to German Atomic Law, two different strategies are possible, i.e. direct dismantling and safe enclosure before dismantling. Both approaches have their advantages and disadvantages. Taking into account the site and plant specific conditions the optimal strategy can be evaluated. Both approaches have been applied in Germany in the past. The German Atomic Law and the Radiation Protection Ordinance (June 2002) were adapted recently (July 2002). Additionally, the life operation time of the German NPP's was fixed in a new law (April 2002): Orderly Termination of the Commercial Production of Nuclear Electricity. These issues have made it necessary for the power utilities to review the strategies applied. As long as the final disposal in Germany is still an open issue, the construction of local Interim Stores is necessary to be able to dismantle a NPP. The basic strategies are not excluding each other and it seems clear today, that the optimal approach is a combination of these strategies, e.g. dismantling of all auxiliary systems and leaving activated parts for a longer SE period. Within this approach the advantages of both basic strategies have been integrated in one. The EWN GmbH has developed such integrated but still different approaches for the decommissioning projects of the Kernkraftwerke Greifswald (KGR) and the Arbeitsgemeinschaft Versuchsreaktor (AVR) Juelich. It can be stated that the decommissioning of a NPP does not present technical issues of concern, but is more a project management issue, although surrounded by sometime intricate political and juridical boundary conditions. A major strategy change is to be expected only when final disposal capacities are available in the future. (authors)

  14. TomoWELD. Precise detection of weld defects; TomoWELD. Defekte in Schweissnaehten praezise erkennen

    Walter, David [Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin (Germany)

    2016-06-15

    Nuclear power plants are complex and technically elaborate systems whose aim is to produce electricity. They must meet the highest safety requirements. Within the reactors, nuclear reactions and radioactive transformations release energy which is used to evaporate water. The steam generated drives turbines that in turn are coupled with generators which convert the kinetic energy provided by the turbines into electrical energy. The process is easy to illustrate but difficult to control and requires technical equipment such as kilometre-long pipe systems. Austenitic steel is frequently used for this purpose because of its high strength and corrosion resistance. The individual pipe components are joined by welding. However, welds may contain hidden defects. Cracks, lack of fusion or pore nests that can remain undetected may have catastrophic consequences. Therefore, all welds in a nuclear power plant, without exception, must be checked. Approved non-destructive methods use ultrasound and X-ray. The technology developed at BAM is called TomoWELD. [German] Kernkraftwerke sind komplexe und technisch aufwendige Anlagen zur Gewinnung von Elektrizitaet. Sie muessen allerhoechsten Sicherheitsanspruechen genuegen. Die bei Kernreaktionen und radioaktiven Umwandlungen freiwerdende Energie wird genutzt, um Wasser zu verdampfen. Der Dampf treibt Turbinen an und die wiederum sind mit Generatoren gekoppelt, welche die durch die Turbinen bereitgestellte kinetische Energie in elektrische Energie umwandeln. Der Prozess laesst sich einfach darstellen, ihn zu steuern ist allerdings kompliziert und erfordert weitere technische Komponenten, wie beispielsweise kilometerlange Rohrleitungssysteme. Wegen seiner hohen Festigkeit sowie Korrosionsbestaendigkeit wird oft austenitischer Stahl dafuer verwendet. Gefuegt werden die einzelnen Rohrteile durch Schweissen. Doch Schweissnaehte koennen viele verborgene Defekte enthalten. Bleiben Risse, Bindefehler oder Porennester unentdeckt, kann das

  15. Core supervision methods and future improvements of the core master/presto system at KKB

    Lundberg, S.; Wenisch, J.; Teeffelen, W.V.

    2000-01-01

    Kernkraftwerk Brunsbuettel (KKB) is a KWU 806 MW e BWR located at the lower river Elbe, in Germany. The reactor has been in operation since 1976 and is now operating in its 14. cycle. The core supervision at KKB is performed with the ABB CORE MASTER system. This system mainly contains the 3-D simulator PRESTO supplied by Studsvik Scandpower A/S. The core supervision is performed by periodic PRESTO 3-D evaluations of the reactor operation state. The power distribution calculated by PRESTO is adapted with the ABB UPDAT program using the on-line LPRM readings. The thermal margins are based on this adapted power distribution. Related to core supervision, the function of the PRESTO/UPDAT codes is presented. The UPDAT method is working well and is capable of reproducing the true core power distribution. The quality of the 3-D calculation is, however, an important ingredient of the quality of the adapted power distribution. The adaptation method as such is also important for this quality. The data quality of this system during steady state and off-rate states (reactor manoeuvres) are discussed by presenting comparisons between PRESTO and UPDAT thermal margin utilisation from Cycle 13. Recently analysed asymmetries in the UPDAT evaluated MCPR values are also presented and discussed. Improvements in the core supervision such as the introduction of advanced modern nodal methods (PRESTO-2) are presented and an alternative core supervision philosophy is discussed. An ongoing project with the goal to update the data and result presentation interface (GUI) is also presented. (authors)

  16. The term 'danger' according to the act on protection against nuisances - assessment of incidents on account of external effects

    Rehbinder, E.

    1976-01-01

    The author deliberates critically on the opinion taken up in the judgments of the Higher Administrative Court at Lueneburg dated February 25th, 1975 and June 27th, 1975 in the case of Dow Chemical, according to which the facilities subject to a licence under the Federal act on protection against nuisances have to be erected in such a way that dangers for the general public and the neighbourhood (in this case danger through gas cloud explosions from a chlorine plant of the Kernkraftwerk Stade) are excluded. If this view, hitherto only expressed by the OVG Lueneburg in summary proceedings according to section 80 paragraph 5 VwGO, gains acceptance, then, in the opinion of the author, the open air construction of the big chemical industry's plants would be illegal to a large extent. While defining the term of danger in police law, Rehbinder applies the term of probability and proportionateness to the term of danger in section 3 BImSchG. On the other hand, the term of danger would have to be taken in a wider sense in section 1 No. 2 and section 7 sub-section No. 2 and 4 Atomic Energy Act, because of the danger potential being here bigger in the long run. In a final conclusion with a view to politics and law, the author states, amongst other things, the following: an exaggerated safety philosophy hides the danger of a political discrediting of the whole environment protection idea, a danger which ought to weigh in the end more heavily than the minute remaining risk for the life and the health of people if a facility which has to have a licence is not protected against absolutely unlikely external incidents. (orig./HP) [de

  17. Practical decommissioning experience with nuclear installations in the European Community

    Skupinski, E.

    1993-01-01

    Initiated by the Commission of the European Communities (CEC), this seminar was jointly organized by Kernkraftwerke RWE Bayernwerk GmbH (KRB) and the CEC at Gundremmingen-Guenzburg (D), where the former KRB-A BWR is presently being dismantled. The meeting aimed at gathering a limited number of European experts for the presentation and discussion of operations, the results and conclusions on techniques and procedures presently applied in the dismantling of large-scale nuclear installations in the European Community. Besides the four pilot dismantling projects of the presently running third R and D programme (1989-93) of the European Community on decommissioning of nuclear installations (WAGR, BR-3 PWR, KRB-A BWR and AT-1 FBR fuel reprocessing), the organizers selected the presentation of topics on the following facilities which have a significant scale and/or representative features and are presently being dismantled: the Magnox reprocessing pilot plant at Sellafield, the HWGCR EL4 at Monts d'Arree, the operation of an on-site melting furnace for G2/G3 GCR dismantling waste at Marcoule, an EdF confinement conception of shut-down LWRs for deferred dismantling, and the technical aspects of the Greifswald WWER type NPPs decommissioning. This was completed by a presentation on the decommissioning of material testing reactors in the United Kingdom and by an overview on the conception and implementation of two EC databases on tools, costs and job doses. The seminar concluded with a guided visit of the KRB-A dismantling site. This meeting was attended by managers concerned by the decommissioning of nuclear installations within the European Community, either by practical dismantling work or by decision-making functions. Thereby, the organizers expect to have contributed to the achievement of decommissioning tasks under optimal conditions - with respect to safety and economics - by making available a complete and updated insight into on-going dismantling projects and by

  18. Monitoring solar energetic particles with an armada of European spacecraft and the new automated SEPF (Solar Energetic Proton Fluxes) Tool

    Sandberg, I.; Daglis, I. A.; Anastasiadis, A.; Balasis, G.; Georgoulis, M.; Nieminen, P.; Evans, H.; Daly, E.

    2012-01-01

    Solar energetic particles (SEPs) observed in interplanetary medium consist of electrons, protons, alpha particles and heavier ions (up to Fe), with energies from dozens of keVs to a few GeVs. SEP events, or SEPEs, are particle flux enhancements from background level ( 30 MeV. The main part of SEPEs results from the acceleration of particles either by solar flares and/or by interplanetary shocks driven by Coronal Mass Ejections (CMEs); these accelerated particles propagate through the heliosphere, traveling along the interplanetary magnetic field (IMF). SEPEs show significant variability from one event to another and are an important part of space weather, because they pose a serious health risk to humans in space and a serious radiation hazard for the spacecraft hardware which may lead to severe damages. As a consequence, engineering models, observations and theoretical investigations related to the high energy particle environment is a priority issue for both robotic and manned space missions. The European Space Agency operates the Standard Radiation Environment Monitor (SREM) on-board six spacecraft: Proba-1, INTEGRAL, Rosetta, Giove-B, Herschel and Planck, which measures high-energy protons and electrons with a fair angular and spectral resolution. The fact that several SREM units operate in different orbits provides a unique chance for comparative studies of the radiation environment based on multiple data gathered by identical detectors. Furthermore, the radiation environment monitoring by the SREM unit onboard Rosetta may reveal unknown characteristics of SEPEs properties given the fact that the majority of the available radiation data and models only refer to 1AU solar distances. The Institute for Space Applications and Remote Sensing of the National Observatory of Athens (ISARS/NOA) has developed and validated a novel method to obtain flux spectra from SREM count rates. Using this method and by conducting detailed scientific studies we have showed in

  19. Comparison of 10 single and stepped methods to identify frail older persons in primary care: diagnostic and prognostic accuracy.

    Sutorius, Fleur L; Hoogendijk, Emiel O; Prins, Bernard A H; van Hout, Hein P J

    2016-08-03

    Many instruments have been developed to identify frail older adults in primary care. A direct comparison of the accuracy and prevalence of identification methods is rare and most studies ignore the stepped selection typically employed in routine care practice. Also it is unclear whether the various methods select persons with different characteristics. We aimed to estimate the accuracy of 10 single and stepped methods to identify frailty in older adults and to predict adverse health outcomes. In addition, the methods were compared on their prevalence of the identified frail persons and on the characteristics of persons identified. The Groningen Frailty Indicator (GFI), the PRISMA-7, polypharmacy, the clinical judgment of the general practitioner (GP), the self-rated health of the older adult, the Edmonton Frail Scale (EFS), the Identification Seniors At Risk Primary Care (ISAR PC), the Frailty Index (FI), the InterRAI screener and gait speed were compared to three measures: two reference standards (the clinical judgment of a multidisciplinary expert panel and Fried's frailty criteria) and 6-years mortality or long term care admission. Data were used from the Dutch Identification of Frail Elderly Study, consisting of 102 people aged 65 and over from a primary care practice in Amsterdam. Frail older adults were oversampled. The accuracy of each instrument and several stepped strategies was estimated by calculating the area under the ROC-curve. Prevalence rates of frailty ranged from 14.8 to 52.9 %. The accuracy for recommended cut off values ranged from poor (AUC = 0.556 ISAR-PC) to good (AUC = 0.865 gait speed). PRISMA-7 performed best over two reference standards, GP predicted adversities best. Stepped strategies resulted in lower prevalence rates and accuracy. Persons selected by the different instruments varied greatly in age, IADL dependency, receiving homecare and mood. We found huge differences between methods to identify frail persons in prevalence

  20. Dealing with Non-stationarity in Intensity-Frequency-Duration Curve

    Rengaraju, S.; Rajendran, V.; C T, D.

    2017-12-01

    Extremes like flood and drought are becoming frequent and more vulnerable in recent times, generally attributed to the recent revelation of climate change. One of the main concerns is that whether the present infrastructures like dams, storm water drainage networks, etc., which were designed following the so called `stationary' assumption, are capable of withstanding the expected severe extremes. Stationary assumption considers that extremes are not changing with respect to time. However, recent studies proved that climate change has altered the climate extremes both temporally and spatially. Traditionally, the observed non-stationary in the extreme precipitation is incorporated in the extreme value distributions in terms of changing parameters. Nevertheless, this raises a question which parameter needs to be changed, i.e. location or scale or shape, since either one or more of these parameters vary at a given location. Hence, this study aims to detect the changing parameters to reduce the complexity involved in the development of non-stationary IDF curve and to provide the uncertainty bound of estimated return level using Bayesian Differential Evolutionary Monte Carlo (DE-MC) algorithm. Firstly, the extreme precipitation series is extracted using Peak Over Threshold. Then, the time varying parameter(s) is(are) detected for the extracted series using Generalized Additive Models for Location Scale and Shape (GAMLSS). Then, the IDF curve is constructed using Generalized Pareto Distribution incorporating non-stationarity only if the parameter(s) is(are) changing with respect to time, otherwise IDF curve will follow stationary assumption. Finally, the posterior probability intervals of estimated return revel are computed through Bayesian DE-MC approach and the non-stationary based IDF curve is compared with the stationary based IDF curve. The results of this study emphasize that the time varying parameters also change spatially and the IDF curves should incorporate non

  1. Neighborhood diversity of large trees shows independent species patterns in a mixed dipterocarp forest in Sri Lanka.

    Punchi-Manage, Ruwan; Wiegand, Thorsten; Wiegand, Kerstin; Getzin, Stephan; Huth, Andreas; Gunatilleke, C V Savitri; Gunatilleke, I A U Nimal

    2015-07-01

    Interactions among neighboring individuals influence plant performance and should create spatial patterns in local community structure. In order to assess the role of large trees in generating spatial patterns in local species richness, we used the individual species-area relationship (ISAR) to evaluate the species richness of trees of different size classes (and dead trees) in circular neighborhoods with varying radius around large trees of different focal species. To reveal signals of species interactions, we compared the ISAR function of the individuals of focal species with that of randomly selected nearby locations. We expected that large trees should strongly affect the community structure of smaller trees in their neighborhood, but that these effects should fade away with increasing size class. Unexpectedly, we found that only few focal species showed signals of species interactions with trees of the different size classes and that this was less likely for less abundant focal species. However, the few and relatively weak departures from independence were consistent with expectations of the effect of competition for space and the dispersal syndrome on spatial patterns. A noisy signal of competition for space found for large trees built up gradually with increasing life stage; it was not yet present for large saplings but detectable for intermediates. Additionally, focal species with animal-dispersed seeds showed higher species richness in their neighborhood than those with gravity- and gyration-dispersed seeds. Our analysis across the entire ontogeny from recruits to large trees supports the hypothesis that stochastic effects dilute deterministic species interactions in highly diverse communities. Stochastic dilution is a consequence of the stochastic geometry of biodiversity in species-rich communities where the identities of the nearest neighbors of a given plant are largely unpredictable. While the outcome of local species interactions is governed for each

  2. Russia's nuclear industry - an overview; Russlands Kernenergiewirtschaft: Zustand, Probleme, Perspektiven

    Tscherkassov, V. [Konzern ROSENERGOATOM, Moskau (Russian Federation)

    2000-04-01

    After the Chernobyl disaster, improvements in materials and in training were made everywhere. As a result, the quality of operation of Russian reactors now is in third place after Germany and Japan. At the present time, it is becoming more and more evident that Russia will have no future in the absence of a nuclear power industry. This is due not only to the country's geographic and socio-economic features, its large territory, and the mismatch between the major energy resources in Siberia and the centers of energy consumption in the European part of Russia, but also to the fact that there is no technology other than nuclear at present which would be able to generate the volume of electricity required after the end of the 'natural gas break'. The generation of electricity in nuclear power plants contributed from 1999 on amounted to a share of approx. 15 per cent in all of Russia; 30 per cent in the European part of Russia and in the central supply region; of this share, 60 per cent in the central Chernozem region; 41 per cent in the northwestern supply region; 70 per cent in the northwest of the autonomous Chukchen region; 40 per cent in the FOREM single electricity market. The same percentages apply to electricity exports. (orig.) [German] Nach der Katastrophe von Tschernobyl wurden ueberall Verbesserungen bei Material und Ausbildung umgesetzt. Die Folge ist, dass heute die Betriebsqualitaet der russischen Reaktoren direkt hinter Deutschland und Japan rangiert. Kernkraftwerke spielen in der Wirtschaft des Landes eine wesentliche Rolle. Rentabel wirtschaftende KKW grosser Leistung werden an den Knotenpunkten des Versorgungsnetzes im Grundlastbereich betrieben und sichern einen stabilen Betrieb des gesamten Energieverbundsystems Russlands. Aus diesem Grund ist Russland an einem stabilen und sicheren Betrieb seiner KKW interessiert. Gegenwaertig zeigt sich immer deutlicher, dass Russland ohne Kernenergiewirtschaft keine entsprechende Zukunft hat. Dies

  3. Optimization potential in maintenance; Optimierungspotenzial in der Instandhaltung

    Janisch, H. [EnBW Kraftwerke AG, Kernkraftwerk Philippsburg (Germany)

    2001-04-01

    hohen Zuverlaessigkeit der Anlagen sind diese kapazitaetsbestimmenden Einfluesse auf die Erzeugungskosten aber praktisch ausgeschoepft. Somit steht der Kostenterm im Blickpunkt von Optimierungsansaetzen, d.h. bei den bestehenden Kernkraftwerken insbesondere die Instandhaltungskosten. Bei einem hohen und sich weiter entwickelnden Sicherheitsniveau kann dabei mit den zunehmenden Betriebserfahrungen von der vorbeugenden Instandhaltung auf die kostenoptimierte zustandsorientierte Instandhaltung uebergegangen werden. Weitere Massnahmen fuer fortgeschrittene Instandhaltungsstrategien betreffen die Arbeitsorganisation, das Personalmanagement sowie standortuebergreifende Planungen fuer den Personal- und Anlageneinsatz. Wichtige Komponenten sind EDV-gestuetzte Betriebsfuehrungssysteme, mit denen die komplexen Aufgaben geplant, durchgefuehrt, kontrolliert und analysiert werden koennen. Ziel dieser Massnahmen ist ein weiter optimierter Betrieb der Kernkraftwerke mit hoechster, dem technischen Fortschritt folgender, Sicherheit, bei demonstrierten wettbewerbsfaehigen Stromerzeugungskosten. (orig.)

  4. Breeder development and breeder strategies worldwide; Brueterentwicklung und Brueterstrategien weltweit

    Marth, W. [Stabsabteilung Finanzen/Controlling, Bereich Stillegung Nuklearer Anlagen, Forschungszentrum Karlsruhe GmbH (Germany)

    1997-05-01

    indische Versuchsbrueter FBTR ist in der Inbetriebnahmephase von mancherlei technischen Problemen geplagt. Der amerikanische Schnelle Reaktor FFT wird seit Jahren im heissen, aber nichtnuklearen Zustand gehalten, da sich die Politiker ueber seine Bestimmung nicht einigen koennen. Das Schicksal des deutschen Brueterprototyps SNR-300 ist bekannt: Dem Kernkraftwerk Kalkar wurde sechs Jahre lang die Betriebsgenehmigung versagt. Nach seiner politisch erzwungenen Stillegung im Jahre 1991 wurde es teilweise demontiert und in einen Freizeitpark umgewandelt. (orig.)

  5. Real and mythical consequences of Chernobyl accident

    Osmachkin, V.S.

    1999-01-01

    This presentation describes the public Unacceptance of Nuclear Power as a consequence of Chernobyl Accident, an accident which was a severest event in the history of the nuclear industry. It was a shock for everybody, who has been involved in nuclear power programs. But nobody could expect that it was also the end romantic page in the nuclear story. The scale of the detriment was a great, and it could be compared with other big technological man-made catastrophes. But immediately after an accident mass media and news agencies started to transmit an information with a great exaggerations of the consequences of the event. In a report on the Seminar T he lessons of the Chernobyl - 1' in 1996 examples of such incorrect information, were cited. Particularly, in the mass media it was declared that consequences of the accident could be compared with a results of the second world war, the number of victims were more than hundred thousand people, more than million of children have the serious health detriments. Such and other cases of the misconstruction have been called as myths. The real consequences of Chernobyl disaster have been summed on the International Conference 'One decade after Chernobyl' - 2, in April 1996. A very important result of the Chernobyl accident was a dissemination of stable unacceptance of the everything connected with 'the atom'. A mystic horror from invisible mortal radiation has been inspired in the masses. And from such public attitude the Nuclear Power Programs in many countries have changed dramatically. A new more pragmatic and more careful atomic era started with a slogan: 'Kernkraftwerk ? Nein, danke'. No doubt, a Chernobyl accident was a serious technical catastrophe in atomic industry. The scale of detriment is connected with a number of involved peoples, not with a number of real victims. In comparison with Bhopal case, earthquakes, crashes of the airplanes, floods, traffic accidents and other risky events of our life - the Chernobyl is

  6. Piercing of corporate veil of nuclear companies; Durchgriffshaftung der Atomkonzerne

    Frenz, Walter [RWTH Aachen Univ. (Germany). Lehr- und Forschungsgebiet Berg-, Umwelt- und Europarecht

    2015-11-15

    Belreibergesellschaften im Fall der Beendigung der Beherrschungs- und Ergebnisabfuehrungsvertraege fuer die Nuklearverbindlichkeiten nur sehr eingeschraenkt, und zwar in zweifacher Hinsicht: Der Anspruch ist lediglich auf Sicherungsleistung gerichtet und nicht auf Kostenuebernahme und zudem entsprechend der Judikatur auf fuenf Jahre nach seiner Begruendung begrenzt; fuer den Bereich des Umwandlungsrechts gelten vergleichbare Regelungen. Dabei dauert der Rueckbau eines Kernkraftwerks allein schon 20 Jahre und ein Endlager duerfte vor 2050 nicht verfuegbar sein.

  7. Analysis of effects of pellet-cladding bonding on trapping of the released fission gases in high burnup KKL BWR fuels

    Brankov, Vladimir [Laboratory for Reactor Physics and Systems Behaviour at the Paul Scherrer Institute, 5232 Villigen-PSI (Switzerland); Swiss Federal Institute of Technology Lausanne (EPFL), Route Cantonale, 1015 Lausanne (Switzerland); Khvostov, Grigori; Mikityuk, Konstantin [Laboratory for Reactor Physics and Systems Behaviour at the Paul Scherrer Institute, 5232 Villigen-PSI (Switzerland); Pautz, Andreas [Laboratory for Reactor Physics and Systems Behaviour at the Paul Scherrer Institute, 5232 Villigen-PSI (Switzerland); Swiss Federal Institute of Technology Lausanne (EPFL), Route Cantonale, 1015 Lausanne (Switzerland); Restani, Renato; Abolhassani, Sousan [Laboratory for Nuclear Materials at the Paul Scherrer Institute, 5232 Villigen-PSI (Switzerland); Ledergerber, Guido [Kernkraftwerk Leibstadt, 5325 Leibstadt (Switzerland); Wiesenack, Wolfgang [Institutt for Energiteknikk - OECD Halden Reactor Project, Os Allé 5, 1777 Halden (Norway)

    2016-08-15

    Highlights: • Explanation for the scatter in measured fission gas release in high-BU BWR fuel rods. • Partial fuel-clad bond layer formation in high-BU BWR fuel. • Hypothesis for fission gas trapping facilitated by the pellet-cladding bond layer. • Correlation between burnup asymmetry and the quantity of trapped fission gas. • Implications of the trapped FG in LOCA transient. - Abstract: The first part of the paper presents results of a numerical analysis of the fuel behavior during base irradiation in the Kernkraftwerk Leibstadt Boiling Water Reactor (KKL BWR) using EPRI’s FALCON code coupled to GRSW-A – an advanced model for fuel swelling and fission gas release. Post-irradiation examinations conducted at the Paul Scherrer Institute’s (PSI) hot laboratory gave evidence of a distinct circumferential non-uniformity of local burnup at pellet surfaces. For several fuel samples, intact pellet-cladding bonding areas on the high burnup sides of the pellets at high burnup above ∼70 MWd/kgU were observed. It is hypothesized that a part of the fission gases, which are expected to be released by those areas, can be trapped and do not reach the rod plenum. In this paper, a simple approach to modeling of fission gas trapping is employed which reveals a potential correlation between the position of the rod within the fuel assembly (and therefore the degree of circumferential burnup non-uniformity) and the degree of fission gas trapping. A model is suggested to correlate the amount of locally trapped gas with the integral of the local contact pressure and the degree of circumferential burnup non-uniformity. The model is calibrated with available measurements of FGR from rod puncturing at the level of the plenums. In future work, the hypothesis about the axial distribution of trapped fission gas will be extrapolated to the Loss-Of-Coolant Accident (LOCA) analysis as an attempt to explain the fission gas release observed in some samples fabricated from

  8. Mediterranean diet and inflammaging within the hormesis paradigm.

    Martucci, Morena; Ostan, Rita; Biondi, Fiammetta; Bellavista, Elena; Fabbri, Cristina; Bertarelli, Claudia; Salvioli, Stefano; Capri, Miriam; Franceschi, Claudio; Santoro, Aurelia

    2017-06-01

    A coherent set of epidemiological data shows that the Mediterranean diet has beneficial effects capable of preventing a variety of age-related diseases in which low-grade, chronic inflammation/inflammaging plays a major role, but the underpinning mechanism(s) is/are still unclear. It is suggested here that the Mediterranean diet can be conceptualized as a form of chronic hormetic stress, similar to what has been proposed regarding calorie restriction, the most thoroughly studied nutritional intervention. Data on the presence in key Mediterranean foods of a variety of compounds capable of exerting hormetic effects are summarized, and the mechanistic role of the nuclear factor erythroid 2 pathway is highlighted. Within this conceptual framework, particular attention has been devoted to the neurohormetic and neuroprotective properties of the Mediterranean diet, as well as to its ability to maintain an optimal balance between pro- and anti-inflammaging. Finally, the European Commission-funded project NU-AGE is discussed because it addresses a number of variables not commonly taken into consideration, such as age, sex, and ethnicity/genetics, that can modulate the hormetic effect of the Mediterranean diet. © The Author(s) 2017. Published by Oxford University Press on behalf of the International Life Sciences Institute.

  9. Engineered coryneform bacteria as a bio-tool for arsenic remediation.

    Villadangos, Almudena F; Ordóñez, Efrén; Pedre, Brandán; Messens, Joris; Gil, Jose A; Mateos, Luis M

    2014-12-01

    Despite current remediation efforts, arsenic contamination in water sources is still a major health problem, highlighting the need for new approaches. In this work, strains of the nonpathogenic and highly arsenic-resistant bacterium Corynebacterium glutamicum were used as inexpensive tools to accumulate inorganic arsenic, either as arsenate (As(V)) or arsenite (As(III)) species. The assays made use of "resting cells" from these strains, which were assessed under well-established conditions and compared with C. glutamicum background controls. The two mutant As(V)-accumulating strains were those used in a previously published study: (i) ArsC1/C2, in which the gene/s encoding the mycothiol-dependent arsenate reductases is/are disrupted, and (ii) MshA/C mutants unable to produce mycothiol, the low molecular weight thiol essential for arsenate reduction. The As(III)-accumulating strains were either those lacking the arsenite permease activities (Acr3-1 and Acr3-2) needed in As(III) release or recombinant strains overexpressing the aquaglyceroporin genes (glpF) from Corynebacterium diphtheriae or Streptomyces coelicolor, to improve As(III) uptake. Both genetically modified strains accumulated 30-fold more As(V) and 15-fold more As(III) than the controls. The arsenic resistance of the modified strains was inversely proportional to their metal accumulation ability. Our results provide the basis for investigations into the use of these modified C. glutamicum strains as a new bio-tool in arsenic remediation efforts.

  10. Riboflavin content of coelomocytes in earthworm (Dendrodrilus rubidus) field populations as a molecular biomarker of soil metal pollution

    Plytycz, Barbara; Lis-Molenda, Urszula; Cygal, Malgorzata; Kielbasa, Edyta; Grebosz, Anna; Duchnowski, Michal; Andre, Jane; Morgan, A. John

    2009-01-01

    The effect of Pb + Zn on coelomocyte riboflavin content in the epigeic earthworm Dendrodrilus rubidus inhabiting three metalliferous soils and one reference soil was measured by flow cytometry and spectrofluorimetry. A reciprocal polluted↔unpolluted worm transfer experiment (4-week exposure) was also performed. High proportions of autofluorescent eleocytes were counted in worms from all localities, but intense riboflavin-derived autofluorescence was detectable only in reference worm eleocytes. Other findings were: (i) fluorophore(s) other than riboflavin is/are responsible for eleocyte autofluorescence in residents of metalliferous soils; (ii) riboflavin content was reduced in the eleocytes of worms transferred from unpolluted to metal-polluted soil; (iii) the riboflavin content of D. rubidus eleocytes is a promising biomarker of exposure; (iv) COII mitochondrial genotyping revealed that the reference population is genetically distinct from the three mine populations; (v) metal exposure rather than genotype is probably the main determinant of inter-population differences in eleocyte riboflavin status. - Soil metal pollution reduces riboflavin content of earthworm eleocytes.

  11. The Inflammation Response to DEHP through PPARγ in Endometrial Cells

    Qiansheng Huang

    2016-03-01

    Full Text Available Epidemiological studies have shown the possible link between phthalates and endometrium-related gynecological diseases, however the molecular mechanism(s behind this is/are still unclear. In the study, both primary cultured endometrial cells and an endometrial adenocarcinoma cell line (Ishikawa were recruited to investigate the effects of di-(2-ethylhexyl phthalate (DEHP at human-relevant concentrations. The results showed that DEHP did not affect the viability of either type of cell, which showed different responses to inflammation. Primary cultured cells showed stronger inflammatory reactions than the Ishikawa cell line. The expression of inflammatory factors was induced both at the mRNA and protein levels, however the inflammation did not induce the progress of epithelial-mesenchymal transition (EMT as the protein levels of EMT markers were not affected after exposure to either cell type. Further study showed that the mRNA levels of peroxisome proliferator-activated receptor gamma (PPARγ wereup-regulated after exposure. In all, our study showed that human-relevant concentrations of DEHP could elicit the inflammatory response in primary cultured endometrial cells rather than in Ishikawa cell line. PPARγ may act as the mediating receptor in the inflammation reaction.

  12. Quousque tandem

    Eyermann, E.

    1984-01-01

    The author critically comments the decisions of the Regensburg Administrative Court concerning the construction of the Isar-2 reactor, judgments which have met with astonishment. The author's criticism concentrates on the following: The fact that the administrative procedure for the licensing of nuclear power plants from design up to commissioning has - for a variety of plausible reasons - been split up into several stages consistent in themselves through interconnected with each other, inevitably defines - and restricts - the legal framework governing the decisions to be taken in every particular stage, both with regard to the rights of the owner or operator of the plant, any third parties, and the duties of the courts. Hence courts are restricted to examine the conditions in a particular stage of development of the project. This is why the considerations of the Regensburg court concerning future developments of energy demand and supply in the FRG and in Bavaria in particular are inappropriate, and incorrect, too. It is generally acknowledged by now that issues of this kind do not fall under the competence of our courts. When reading the judgments, the author says, one gets the impression that the decisions of the court have been taken on the basis of considerations which have been overshadowed by the fear of nuclear hazards emanating from nuclear power plants. (orig./HSCH) [de

  13. Localization and characterization of angiotensin II receptor binding and angiotensin converting enzyme in the human medulla oblongata.

    Allen, A M; Chai, S Y; Clevers, J; McKinley, M J; Paxinos, G; Mendelsohn, F A

    1988-03-08

    Angiotensin II receptor and angiotensin converting enzyme distributions in the human medulla oblongata were localised by quantitative in vitro autoradiography. Angiotensin II receptors were labelled with the antagonist analogue 125I-[Sar1, Ile8] AII while angiotensin converting enzyme was labelled with 125I-351A, a derivative of the specific converting enzyme inhibitor, lisinopril. Angiotensin II receptor binding and angiotensin converting enzyme are present in high concentrations in the nucleus of the solitary tract, the dorsal motor nucleus of vagus, the rostral and caudal ventrolateral reticular nucleus, and in a band connecting the dorsal and ventral regions. In the rostral and caudal ventrolateral reticular nucleus, angiotensin II receptors are distributed in a punctate pattern that registers with neuronal cell bodies. The distribution and density of these cell bodies closely resemble those of catecholamine-containing neurones mapped by others. In view of the known interactions of angiotensin II with both central and peripheral catecholamine-containing neurons of laboratory animals, the current anatomical findings suggest similar interactions between these neuroactive compounds in the human central nervous system. The presence of angiotensin II receptors and angiotensin converting enzyme in the nucleus of the solitary tract, dorsal motor nucleus of vagus, and rostral and caudal ventrolateral reticular nucleus demonstrates sites for central angiotensin II to exert its known actions on vasopressin release and autonomic functions including blood pressure control. These data also suggest a possible interaction between angiotensin II and central catecholeminergic systems.

  14. Potential of Carbon Nanotube Reinforced Cement Composites as Concrete Repair Material

    Tanvir Manzur

    2016-01-01

    Full Text Available Carbon nanotubes (CNTs are a virtually ideal reinforcing agent due to extremely high aspect ratios and ultra high strengths. It is evident from contemporary research that utilization of CNT in producing new cement-based composite materials has a great potential. Consequently, possible practical application of CNT reinforced cementitious composites has immense prospect in the field of applied nanotechnology within construction industry. Several repair, retrofit, and strengthening techniques are currently available to enhance the integrity and durability of concrete structures with cracks and spalling, but applicability and/or reliability is/are often limited. Therefore, there is always a need for innovative high performing concrete repair materials with good mechanical, rheological, and durability properties. Considering the mechanical properties of carbon nanotubes (CNTs and the test results of CNT reinforced cement composites, it is apparent that such composites could be used conveniently as concrete repair material. With this end in view, the applicability of multiwalled carbon nanotube (MWNT reinforced cement composites as concrete repair material has been evaluated in this study in terms of setting time, bleeding, and bonding strength (slant shear tests. It has been found that MWNT reinforced cement mortar has good prospective as concrete repair material since such composites exhibited desirable behavior in setting time, bleeding, and slant shear.

  15. Could Some Geriatric Characteristics Hinder the Prescription of Anticoagulants in Atrial Fibrillation in the Elderly?

    Paule Denoël

    2014-01-01

    Full Text Available Several studies have reported underprescription of anticoagulants in atrial fibrillation (AF. We conducted an observational study on 142 out of a total of 995 consecutive ≥75 years old patients presenting AF (14% when admitted in an emergency unit of a general hospital, in search of geriatric characteristics that might be associated with the underprescription of anticoagulation therapy (mostly antivitamin K at the time of the study. The following data was collected from patients presenting AF: medical history including treatment and comorbidities, CHADS2 score, ISAR scale (frailty, Lawton’s scale (ADL, GDS scale (mood status, MUST (nutrition, and blood analysis (INR, kidney function, and albumin. Among those patients for who anticoagulation treatment was recommended (73%, only 61% were treated with it. In the group with anticoagulation therapy, the following characteristics were observed more often than in the group without such therapy: a recent (≤6 months hospitalization and medical treatment including digoxin or based on >3 different drugs. Neither the value of the CHADS2 score, nor the geriatric characteristics could be correlated with the presence or the absence of an anticoagulation therapy. More research is thus required to identify and clarify the relative importance of patient-, physician-, and health care system-related hurdles for the prescription of oral anticoagulation therapy in older patients with AF.

  16. Effectiveness of Tuned Mass Dampers in Seismic Response Control of Isolated Bridges Including Soil-Structure Interaction

    Said Elias

    Full Text Available Abstract The effect of soil-structure interaction (SSI on the dynamic responses of seismically isolated three-span continuous reinforced concrete (RC bridge is investigated. Also, tuned mass damper(s (TMD/s is/are installed to control undesirable bearing displacement, even under the SSI effect. The TMDs are placed at the mid-span of the bridge and each tuned with a modal frequency, while controlling up to first few modes as desirable. The soil surrounding the foundation of pier is modeled by frequency independent coefficients. Dynamic analysis is carried out in time domain using direct integration method. In order to specify the effects of the SSI, the responses of the non-isolated, isolated, and controlled isolated bridge are compared. It is observed that the soil surrounding the pier has significant effects on the bearing displacement of the isolated RC bridges. In addition, it is observed that the seismic responses of isolated RC bridge reduced significantly with installation of the TMDs.

  17. Joint sub-carrier pairing and resource allocation for cognitive networks with adaptive relaying

    Soury, Hamza; Bader, F.; Shaat, M.; Alouini, Mohamed-Slim

    2013-01-01

    Relayed transmission in a cognitive radio (CR) environment could be used to increase the coverage and capacity of communication system that benefits already from the efficient management of the spectrum developed by CR. Furthermore, there are many types of cooperative communications, including decode-and-forward (DAF) and amplify-and-forward (AAF). In this paper, these techniques are combined in an adaptive mode to benefit from its forwarding advantages; this mode is called adaptive relaying protocol (ARP). Moreover, this work focuses on the joint power allocation in a cognitive radio system in a cooperative mode that operates ARP in multi-carrier mode. The multi-carrier scenario is used in an orthogonal frequency division multiplexing (OFDM) mode, and the problem is formulated to maximize the end-to-end rate by searching the best power allocation at the transmitters. This work includes, besides the ARP model, a sub-carrier pairing strategy that allows the relays to switch to the best sub-carrier pairs to increase the throughput. The optimization problem is formulated and solved under the interference and power budget constraints using the sub-gradient algorithm. The simulation results confirm the efficiency of the proposed adaptive relaying protocol in comparison to other relaying techniques. The results show also the consequence of the choice of the pairing strategy. 2013 Stolojescu-Crisan and Isar; licensee Springer.

  18. Clonal Re-Introduction of Endangered Plant Species: The Case of German False Tamarisk in Pre-Alpine Rivers

    Koch, Christiane; Kollmann, Johannes

    2012-08-01

    The scope of re-introduction as a measure for plant species protection is increasing, but as long as no standardized methods are available, species-specific assessments are necessary to determine whether seeds, adult plants or plant fragments should be used. The endangered German False Tamarisk ( Myricaria germanica), which occurs on gravel bars along pre-alpine rivers, is difficult to grow from seeds. Thus, propagation of stem cuttings was investigated as an alternative method. Experiments were conducted in a greenhouse and a field site with three treatments: cutting length 5 or 10 cm, vertical burial 5 or 10 cm, and water level low or high. Plants grown in the greenhouse were transplanted to the River Isar to test establishment of rooted cuttings on gravel bars. The cuttings in the greenhouse showed high survival (34-96 %). Survival and biomass production were greatest for 10-cm cuttings buried at 10-cm depth, while only one of the 5-cm cuttings survived at this depth, and no significant effect of variation in water level was observed. None of the cuttings transplanted to field sites survived, most likely because of drought stress and competition. We conclude that for re-introduction of Myricaria germanica rooted cuttings can be easily produced in large quantities, while transplantation to near-natural environments has to be improved to reduce mortality.

  19. Joint sub-carrier pairing and resource allocation for cognitive networks with adaptive relaying

    Soury, Hamza

    2013-11-09

    Relayed transmission in a cognitive radio (CR) environment could be used to increase the coverage and capacity of communication system that benefits already from the efficient management of the spectrum developed by CR. Furthermore, there are many types of cooperative communications, including decode-and-forward (DAF) and amplify-and-forward (AAF). In this paper, these techniques are combined in an adaptive mode to benefit from its forwarding advantages; this mode is called adaptive relaying protocol (ARP). Moreover, this work focuses on the joint power allocation in a cognitive radio system in a cooperative mode that operates ARP in multi-carrier mode. The multi-carrier scenario is used in an orthogonal frequency division multiplexing (OFDM) mode, and the problem is formulated to maximize the end-to-end rate by searching the best power allocation at the transmitters. This work includes, besides the ARP model, a sub-carrier pairing strategy that allows the relays to switch to the best sub-carrier pairs to increase the throughput. The optimization problem is formulated and solved under the interference and power budget constraints using the sub-gradient algorithm. The simulation results confirm the efficiency of the proposed adaptive relaying protocol in comparison to other relaying techniques. The results show also the consequence of the choice of the pairing strategy. 2013 Stolojescu-Crisan and Isar; licensee Springer.

  20. Bayesian Islamic medication expert system (B-IMES)

    Daud, Hanita; Razali, Radzuan; Jung, Low Tan; Zaida, Shahnaz

    2015-12-01

    This paper discusses on the development of an expert system (ES) that applies Bayesian Probability concept for Islamic Medication practice that is made available on web platform. This ES allows user to choose sickness such as headache, stomachache, toothache and etc that he/she may have and list of symptoms related to the sickness will appear for the user to choose. Once symptom(s) is/are chosen the diagnosis is being carried out to suggest percentage of possible specific sickness such as classic migraine, common migraine, tension headache and etc if headache was chosen. This diagnosis is being carried out using Bayes' Theorem and the ES will suggest the treatments or therapy that he/she needs to perform in reference to Muslim Holy Quran and Hadith. This ES was developed to preserve Islamic medication and to create awareness among the young generation and make it accessible at anytime and anywhere and to save users time to meet Islamic Medication practitioners who are not easily available in Malaysia and other parts of the world.

  1. Riboflavin content of coelomocytes in earthworm (Dendrodrilus rubidus) field populations as a molecular biomarker of soil metal pollution

    Plytycz, Barbara, E-mail: barbara.plytycz@uj.edu.p [Institute of Zoology, Jagiellonian University, Ingardena 6, PL 30-060 Krakow (Poland); Lis-Molenda, Urszula; Cygal, Malgorzata; Kielbasa, Edyta; Grebosz, Anna [Institute of Zoology, Jagiellonian University, Ingardena 6, PL 30-060 Krakow (Poland); Duchnowski, Michal [Institute of Environmental Sciences, Jagiellonian University, Krakow (Poland); Andre, Jane; Morgan, A. John [Cardiff School of Biosciences, Main Building, Cardiff University, Cardiff CF10 3TL, Wales (United Kingdom)

    2009-11-15

    The effect of Pb + Zn on coelomocyte riboflavin content in the epigeic earthworm Dendrodrilus rubidus inhabiting three metalliferous soils and one reference soil was measured by flow cytometry and spectrofluorimetry. A reciprocal pollutedreversibleunpolluted worm transfer experiment (4-week exposure) was also performed. High proportions of autofluorescent eleocytes were counted in worms from all localities, but intense riboflavin-derived autofluorescence was detectable only in reference worm eleocytes. Other findings were: (i) fluorophore(s) other than riboflavin is/are responsible for eleocyte autofluorescence in residents of metalliferous soils; (ii) riboflavin content was reduced in the eleocytes of worms transferred from unpolluted to metal-polluted soil; (iii) the riboflavin content of D. rubidus eleocytes is a promising biomarker of exposure; (iv) COII mitochondrial genotyping revealed that the reference population is genetically distinct from the three mine populations; (v) metal exposure rather than genotype is probably the main determinant of inter-population differences in eleocyte riboflavin status. - Soil metal pollution reduces riboflavin content of earthworm eleocytes.

  2. Role of MicroRNAs in Renin-Angiotensin-Aldosterone System-Mediated Cardiovascular Inflammation and Remodeling

    Maricica Pacurari

    2015-01-01

    Full Text Available MicroRNAs are endogenous regulators of gene expression either by inhibiting translation or protein degradation. Recent studies indicate that microRNAs play a role in cardiovascular disease and renin-angiotensin-aldosterone system- (RAAS- mediated cardiovascular inflammation, either as mediators or being targeted by RAAS pharmacological inhibitors. The exact role(s of microRNAs in RAAS-mediated cardiovascular inflammation and remodeling is/are still in early stage of investigation. However, few microRNAs have been shown to play a role in RAAS signaling, particularly miR-155, miR-146a/b, miR-132/122, and miR-483-3p. Identification of specific microRNAs and their targets and elucidating microRNA-regulated mechanisms associated RAS-mediated cardiovascular inflammation and remodeling might lead to the development of novel pharmacological strategies to target RAAS-mediated vascular pathologies. This paper reviews microRNAs role in inflammatory factors mediating cardiovascular inflammation and RAAS genes and the effect of RAAS pharmacological inhibition on microRNAs and the resolution of RAAS-mediated cardiovascular inflammation and remodeling. Also, this paper discusses the advances on microRNAs-based therapeutic approaches that may be important in targeting RAAS signaling.

  3. Analysis of angiotensin II binding to human platelets: Differences in young and old subjects

    Siebers, M.J.; Goodfriend, T.L.; Ball, D.; Elliott, M.E.

    1990-01-01

    We examined the binding of radiolabeled angiotensin II (AII) to human platelets to characterize the apparent increase in AII receptors observed in older subjects. At 22 degrees C, the amount of radioactivity associated with platelets from older subjects increased continuously for more than 2 hours. The same amount of radioactivity was displaced by addition of unlabeled AII at 30 min and 60 min. In the presence of phenylarsine oxide, in the cold, or when labeled antagonist was the ligand, binding came to equilibrium by 30 min. High pressure liquid chromatography demonstrated that 125 I-AII was the major radioactive compound in the supernatant and platelets after incubation, but the platelets also contained radiolabeled AII fragments. Thus, some degradation accompanied interaction of AII and platelets. Phenylarsine oxide did not prevent degradation of bound AII, suggesting that degradation precedes internalization. On average, maximum binding was greater in older subjects whether platelets were incubated with 125 I-AII alone, with 125 I-AII and phenylarsine oxide to prevent internalization, or when the competitive inhibitor 125 I-sar1,ile8-AII was the radioligand. Variability of binding among subjects also increased with age. Thus, platelets bind, degrade, and internalize AII, and the three processes occur to a greater extent in platelets from some, but not all older subjects

  4. Hyperthyroidism in cats: what's causing this epidemic of thyroid disease and can we prevent it?

    Peterson, Mark

    2012-11-01

    Since first being reported in the late 1970s, there has been a dramatic increase in the prevalence of hyperthyroidism in cats. It is now recognized worldwide as the most common feline endocrine disorder. Hyperthyroidism is an important cause of morbidity in cats older than 10 years of age. It is estimated that over 10% of all senior cats will develop the disorder. Despite its frequency, the underlying cause(s) of this common disease is/are not known, and no one has suggested a means to prevent the disorder. Because of the multiple risk factors that have been described for feline hyperthyroidism, it is likely that more than one factor is involved in its pathogenesis. Continuous, lifelong exposure to environmental thyroid disruptor chemicals or goitrogens in food or water, acting together in an additive or synergistic manner, may first lead to euthyroid goiter and then to autonomous adenomatous hyperplasia, thyroid adenoma and hyperthyroidism. This review draws on published research studies to summarize the available evidence about the risk factors for feline hyperthyroidism. Based on the known goitrogens that may be present in the cat's food, drinking water or environment, it proposes measures that cat owners can implement that might prevent, or reduce the prevalence of, thyroid tumors and hyperthyroidism in their cats.

  5. Aggregation and pH-temperature phase behavior for aggregates of an IgG2 antibody.

    Sahin, Erinc; Weiss, William F; Kroetsch, Andrew M; King, Kevin R; Kessler, R Kendall; Das, Tapan K; Roberts, Christopher J

    2012-05-01

    Monomer unfolding and thermally accelerated aggregation kinetics to produce soluble oligomers or insoluble macroscopic aggregates were characterized as a function of pH for an IgG2 antibody using differential scanning calorimetry (DSC) and size-exclusion chromatography (SEC). Aggregate size was quantified via laser light scattering, and aggregate solubility via turbidity and visual inspection. Interestingly, nonnative oligomers were soluble at pH 5.5 above approximately 15°C, but converted reversibly to visible/insoluble particles at lower temperatures. Lower pH values yielded only soluble aggregates, whereas higher pH resulted in insoluble aggregates, regardless of the solution temperature. Unlike the growing body of literature that supports the three-endotherm model of IgG1 unfolding in DSC, the results here also illustrate limitations of that model for other monoclonal antibodies. Comparison of DSC with monomer loss (via SEC) from samples during thermal scanning indicates that the least conformationally stable domain is not the most aggregation prone, and that a number of the domains remain intact within the constituent monomers of the resulting aggregates. This highlights continued challenges with predicting a priori which domain(s) or thermal transition(s) is(are) most relevant for product stability with respect to aggregation. Copyright © 2012 Wiley Periodicals, Inc.

  6. New decontamination techniques: chemical gels, electropolishing and abrasives

    Brunel, G.; Gauchon, J.P.; Kervegant, Y.; Josso, F.

    1991-01-01

    The decommissioning of nuclear installations requires decontamination techniques that are efficient, simple to apply and producing a small amount of wastes, which are easy to process. With a view to this, three decontamination methods, which appear to be particularly suited to decommissioning, have been studied. These three methods are: - spraying of gels carrying chemical decontaminating agents, - electropolishing with a swab device, - abrasives blasting. After parametric tests on non-radioactive and active samples, the industrial application of these methods in the dismantling of installations was studied. These industrial applications concern: - decontamination of pieces coming from the German BWR ISAR by immersion and gel spraying, - decontamination, mainly by gel spraying, and dismantling of the BRENNILIS bituminisation plant, - decontamination of part of the cooling circuit of the graphite gas reactor G2 by gel spraying, - decontamination of a component of the FBR SuperPhenix, using dry abrasives blasting. During the first three applications, generated secondary wastes volume and form were determined. 33 tabs., 16 figs., 12 refs

  7. Regulatory approaches to, and practice of, PSA in Finland, France, Spain, Sweden, Switzerland, the United Kingdom, and the United States of America

    Baier, M.; Schaefer, A.

    2005-01-01

    Performing level-1 probabilistic safety analyses (PSA) is the established standard in most countries using nuclear power. In addition, level-2 PSA has become more and more widespread over the past few years. However, regulatory requirements and practice differ from country to country, especially with respect to level-2 analyses. In an effort to determine these differences more precisely, the ISaR Institute for Safety and Reliability, on behalf of VGB PowerTech Service GmbH, conducted a study of these seven countries: Finland, France, Spain, Sweden, Switzerland, the United Kingdom, and the United States. The study focused on level-2 PSA carried out by plant operators within the framework of periodic safety reviews. The findings of the study are based on extensive interviews of at least one expert each on the operators' and the authorities' side for each of the seven countries. Points taken into account in particular included the criteria imposed by regulators on PSA carried out by operators; the rank of PSA within the regulatory framework; the required versus the actual scopes of analysis; the objectives and uses of PSA; reviews of the analyses; the methods employed. (orig.)

  8. VHF/UHF imagery and RCS measurements of ground targets in forested terrain

    Gatesman, Andrew J.; Beaudoin, Christopher J.; Giles, Robert H.; Waldman, Jerry; Nixon, William E.

    2002-08-01

    The monostatic VV and HH-polarized radar signatures of several targets and trees have been measured at foliage penetration frequencies (VHF/UHF) by using 1/35th scale models and an indoor radar range operating at X-band. An array of high-fidelity scale model ground vehicles and test objects as well as scaled ground terrain and trees have been fabricated for the study. Radar measurement accuracy has been confirmed by comparing the signature of a test object with a method of moments radar cross section prediction code. In addition to acquiring signatures of targets located on a smooth, dielectric ground plane, data have also been acquired with targets located in simulated wooded terrain that included scaled tree trunks and tree branches. In order to assure the correct backscattering behavior, all dielectric properties of live tree wood and moist soil were scaled properly to match the complex dielectric constant of the full-scale materials. The impact of the surrounding tree clutter on the VHF/UHF radar signatures of ground vehicles was accessed. Data were processed into high-resolution, polar-formatted ISAR imagery and signature comparisons are made between targets in open-field and forested scenarios.

  9. The Role of Information Systems and Technology Competencies for Accounting Education from the Gender Perspective

    Liege Moraes do Carmo

    2015-12-01

    Full Text Available This study aims to examine the importance of obtaining skills in Information Systems (IS and Information Technology (IT for undergraduate students in Accounting from the gender perspective. The sample consisted of undergraduate students in Accounting of six Higher Education Institutions (HEIs located in the state of Rio de Janeiro, divided by gender (male and female. The data collection instrument chosen was the questionnaire, which was distributed between November and December 2014 and was based on the Model Accounting Curriculum Revised (MACR proposed for accountants UN / UNCTAD / ISAR. The data were analyzed using descriptive statistics and the Mann-Whitney test. It has been found that the students from the HEIs surveyed realize the high importance that the possession of skills related to SI and IT has to his academic training regardless of gender issues. In contrast, it appears that female respondents attributed higher levels of importance to obtain knowledge about communications softwares and about softwares that are for generally use while the males turn to more specific softwares applied to business solutions.

  10. Human-Automation Interaction Design for Adaptive Cruise Control Systems of Ground Vehicles

    Hwisoo Eom

    2015-06-01

    Full Text Available A majority of recently developed advanced vehicles have been equipped with various automated driver assistance systems, such as adaptive cruise control (ACC and lane keeping assistance systems. ACC systems have several operational modes, and drivers can be unaware of the mode in which they are operating. Because mode confusion is a significant human error factor that contributes to traffic accidents, it is necessary to develop user interfaces for ACC systems that can reduce mode confusion. To meet this requirement, this paper presents a new human-automation interaction design methodology in which the compatibility of the machine and interface models is determined using the proposed criteria, and if the models are incompatible, one or both of the models is/are modified to make them compatible. To investigate the effectiveness of our methodology, we designed two new interfaces by separately modifying the machine model and the interface model and then performed driver-in-the-loop experiments. The results showed that modifying the machine model provides a more compact, acceptable, effective, and safe interface than modifying the interface model.

  11. Human-Automation Interaction Design for Adaptive Cruise Control Systems of Ground Vehicles.

    Eom, Hwisoo; Lee, Sang Hun

    2015-06-12

    A majority of recently developed advanced vehicles have been equipped with various automated driver assistance systems, such as adaptive cruise control (ACC) and lane keeping assistance systems. ACC systems have several operational modes, and drivers can be unaware of the mode in which they are operating. Because mode confusion is a significant human error factor that contributes to traffic accidents, it is necessary to develop user interfaces for ACC systems that can reduce mode confusion. To meet this requirement, this paper presents a new human-automation interaction design methodology in which the compatibility of the machine and interface models is determined using the proposed criteria, and if the models are incompatible, one or both of the models is/are modified to make them compatible. To investigate the effectiveness of our methodology, we designed two new interfaces by separately modifying the machine model and the interface model and then performed driver-in-the-loop experiments. The results showed that modifying the machine model provides a more compact, acceptable, effective, and safe interface than modifying the interface model.

  12. Appeal in nuclear power proceedings dismissed on the grounds of expiration of the period for lodging an appeal

    Anon.

    1981-01-01

    In its decision of November 18, 1980 - No. 22 B 80 a 796 - the Administrative Court of Bavaria dismissed the appeal lodged against the dismissal of the Administrative Court of Regensburg handed down on March 19, 1980. The complainants had filed a declaratory action concerning the nullity of the licence granted for the Niederaischbach reactor, and for the Isar reactor at Ohu. Their actions were dismissed with costs on the grounds of lacking interest in the declaration - the complainants live a few hundred kilometers away from the sites of the nuclear power plants. The decision of the Administrative Court of Bavaria is based on the fact that the period for lodging appeals had expired. (Exept for the changed decision on costs) the decision of the Administrative Court of Regensburg has become final. The value in litigation of a declaratory action of nullity filed by a private person who denounces the violation of his basic right to life and to inviolability of his person is generally to be assessed at DM 10.000. In case of several complaints filed by different complainants, the subject value of the individual complaints are to be added according to Sect. 5 of the Code of Civil Procedure (ZPO). (orig./HSCH) [de

  13. O ensino da Contabilidade Internacional em cursos de graduação no Brasil: uma pesquisa empírica sobre o perfil dos docentes e recursos didáticos e metodológicos adotados

    Tiago Henrique de Souza Echternacht

    2009-12-01

    Full Text Available A contabilidade é cada vez mais exigida a fornecer informações legíveis e transparentes em qualquer parte do mundo, como resultado do mercado de capitais globalizado. Organizações internacionais de contabilidade tais como a IFAC – Federação Internacional de Contadores, ISAR – Grupo de Trabalho Intergovernamental de Padrões Internacionais de Contabilidade e Relatórios, IASB – Junta de Padrões Internacionais de Contabilidade estão desenvolvendo esforços no sentido de promover o desenvolvimento do conhecimento e habilidades que permitam a profissão contábil ter condições adequadas para atender aos usuários, fornecendo informações úteis sobre a apresentação das demonstrações contábeis seguindo princípios, métodos e padrões internacionais de contabilidade. É compreensível que quanto mais forte a similaridade entre o curriculum internacional e o local, mais forte a evidência da harmonização da educação contábil nesse país. A principal proposta deste trabalho é analisar os recursos didáticos e metodológicos adotados pelos professores da disciplina Contabilidade Internacional nas instituições de ensino superior brasileiras.

  14. Monitoring the Microgravity Environment Quality On-Board the International Space Station Using Soft Computing Techniques

    Jules, Kenol; Lin, Paul P.

    2001-01-01

    This paper presents an artificial intelligence monitoring system developed by the NASA Glenn Principal Investigator Microgravity Services project to help the principal investigator teams identify the primary vibratory disturbance sources that are active, at any moment in time, on-board the International Space Station, which might impact the microgravity environment their experiments are exposed to. From the Principal Investigator Microgravity Services' web site, the principal investigator teams can monitor via a graphical display, in near real time, which event(s) is/are on, such as crew activities, pumps, fans, centrifuges, compressor, crew exercise, platform structural modes, etc., and decide whether or not to run their experiments based on the acceleration environment associated with a specific event. This monitoring system is focused primarily on detecting the vibratory disturbance sources, but could be used as well to detect some of the transient disturbance sources, depending on the events duration. The system has built-in capability to detect both known and unknown vibratory disturbance sources. Several soft computing techniques such as Kohonen's Self-Organizing Feature Map, Learning Vector Quantization, Back-Propagation Neural Networks, and Fuzzy Logic were used to design the system.

  15. Model-Based Evaluation of Urban River Restoration: Conflicts between Sensitive Fish Species and Recreational Users

    Aude Zingraff-Hamed

    2018-05-01

    Full Text Available Urban rivers are socioecological systems, and restored habitats may be attractive to both sensitive species and recreationists. Understanding the potential conflicts between ecological and recreational values is a critical issue for the development of a sustainable river-management plan. Habitat models are very promising tools for the ecological evaluation of river restoration projects that are already concluded, ongoing, or even to be planned. With our paper, we make a first attempt at integrating recreational user pressure into habitat modeling. The objective of this study was to analyze whether human impact is likely to hinder the re-establishment of a target species despite the successful restoration of physical habitat structures in the case of the restoration of the Isar River in Munich (Germany and the target fish species Chondostroma nasus L. Our analysis combined high-resolution 2D hydrodynamic modeling with mapping of recreational pressure and used an expert-based procedure for modeling habitat suitability. The results are twofold: (1 the restored river contains suitable physical habitats for population conservation but has low suitability for recruitment; (2 densely used areas match highly suitable habitats for C. nasus. In the future, the integrated modeling procedure presented here may allow ecological refuge for sensitive target species to be included in the design of restoration and may help in the development of visitor-management plans to safeguard biodiversity and recreational ecosystem services.

  16. Visual Impairment/Increased Intracranial Pressure (VIIP): Layman's Summary

    Fogarty, Jennifer

    2011-01-01

    To date NASA has documented that seven long duration astronauts have experienced in-flight and post-flight changes in vision and eye anatomy including degraded distant vision, swelling of the back of the eye, and changes in the shape of the globe. We have also documented in a few of these astronauts post-flight, increases in the pressure of the fluid that surrounds the brain and spinal cord. This is referred to as increased intracranial pressure (ICP). The functional and anatomical changes have varied in severity and duration. In the post-flight time period, some individuals have experienced a return to a pre-flight level of visual function while others have experienced changes that remain significantly altered compared to pre-flight. In addition, the increased ICP also persists in the post-flight time period. Currently, the underlying cause or causes of these changes is/are unknown but the spaceflight community at NASA suspects that the shift of blood toward the head and the changes in physiology that accompany it, such as increased intracranial pressure, play a significant role.

  17. Mode switching control of dual-evaporator air-conditioning systems

    Lin, J.-L.; Yeh, T.-J.

    2009-01-01

    Modern air-conditioners incorporate variable-speed compressors and variable-opening expansion valves as the actuators for improving cooling performance and energy efficiency. These actuators have to be properly feedback-controlled; otherwise the systems may exhibit even poorer performance than the conventional machines which use fixed-speed compressors and mechanical expansion valves. Particularly for an air-conditioner with multiple evaporators, there are occasions that the machine is operated in a mode that only selected evaporator(s) is(are) turned on, and switching(s) between modes occurs(occur) during the control process. In this case, one needs to have more carefully designed control and switching strategies to ensure the system performance. In this paper, a framework for mode switching control of the dual-evaporator air-conditioning (DEAC) system is proposed. The framework is basically an integration of a controller and a dynamic compensator. The controller, which possesses the flow-distribution capability and assumes both evaporators are on throughout the control process, is intended to provide nominal performance. While mode switching is achieved by varying the reference settings in the controller, the dynamic compensator is used to improve the transient responses immediately after the switching. Experiments indicate that the proposed framework can achieve satisfactory indoor temperature regulation and provide bumpless switching between different modes of operation.

  18. Interaction of a non-peptide agonist with angiotensin II AT1 receptor mutants

    Costa-Neto, Claudio M; Miyakawa, Ayumi A; Pesquero, João B

    2002-01-01

    and inositol phosphate turnover assays in COS-7 cells transiently transfected with the wild-type and mutant forms of the receptor. Mutant receptors bore modifications in the extracellular region: T88H, Y92H, G1961, G196W, and D278E. Compound L-162,313 displaced [125I]-Sar1,Leu8-AngII from the mutants G196I...... and G196W with IC50 values similar to that of the wild-type. The affinity was, however, slightly affected by the D278E mutation and more significantly by the T88H and Y92H mutations. In inositol phosphate turnover assays, the ability of L-162,313 to trigger the activation cascade was compared...... with that of angiotensin II. These assays showed that the G196W mutant reached a relative maximum activation exceeding that of the wild-type receptor; the efficacy was slightly reduced in the G1961 mutant and further reduced in the T88H, Y92H, and D278E mutants. Our data suggest that residues of the extracellular domain...

  19. Organizing of public movement for radiation safety of the population

    Mustafaev, I.

    2003-01-01

    Full text: The possibilities of organizing of public anti nuclear movement in the Caspian region are discussed. The potential of public organizations in the regional countries and international programs and projects supporting this movement is considered. The activity of the following organizations is mentioned: Public movement Semipalatinsk-Nevada (Kazakhstan); Antinuclear movement 'Narin'(Kazakhstan); 'Social - ecological union'(Russia); Association 'Fovgal', scientific-ecological society 'Ekoil'; 'Radioecological society (Azerbaijan); 'Anti-Radiation Movement'(Georgia); 'Radioecology-21'(Georgia). International organizations - Caspian Program ISAR, Scientific Program NATO, IAEA and others play an important role in maintenance of radiation safety of the region. Especially it is necessary to mention the project on Export control of the nuclear materials of double destination (USA). The necessity of support of this movement from public of region is mentioned and an important role in this plays public organizations. The contribution of 'Ruzgar'in organizing of public anti-nuclear movement during the implementation of joint projects 'Along the Caspian', creation of the movement 'For clean Caspian', 'The impact of Gabala radiolocation station on the environment'and others. The following issues are stressed: 1.Lobbying the adoption of legislative and normative acts and their harmonization in a scale of the Caspian region; 2.Creating the cooperation between regional countries for joint solution of regional problems of radiation safety; 3.Increasing of a level of public awareness about this issue and providing public participation in decision-making; 4.Organizing a struggle against 'radiophobia'

  20. Therapeutic efficacy of different brands of albendazole against soil transmitted helminths among students of Mendera Elementary School, Jimma, Southwest Ethiopia.

    Tefera, Ephrem; Belay, Tariku; Mekonnen, Seleshi Kebede; Zeynudin, Ahmed; Belachew, Tefera

    2015-01-01

    Different brands Albendazole are commercially available and the efficacious brand/s is/are required for effective control of STHs infection. Thus, this study is aimed at determining the therapeutic efficacy of different brands of albendazole against soil transmitted helminths among school children of Jimma town. A cross sectional survey for prevalence of geohelminths and a randomized trial for efficacy study of different brands of albendazole was conducted among students Mendera Elementary School from March 29 to April 29, 2010. Positive subjects were randomized into three treatment arms using lottery method. The collected stool samples were examined by the McMaster method. CRs were calculated using SPSS windows version 16 and ERRs were calculated using appropriate formula. Of the 715 school children who had their stools examined, 326 were positive for STHs with a prevalence rate of 45.6%. The cure rates (CR) for A. lumbricoides, T. trichiura and Hookworm were 99.4, 59.9 and 93.7%, respectively. Similarly, the egg reduction rates (ERR) were 97, 99.9 and 99.9% respectively. A statistical significant mean STH egg count difference were observed between pre and post-intervention study (p 0.05). All the three brands of Albendazole tested regardless of the brand type were therapeutically efficacious for Ascariasis, Trichuriasis and Hookworm infections irrespective of the infection status whether it was single or multiple.

  1. Status report on the use of nuclear energy in the Federal Republic of Germany 2016; Statusbericht zur Kernenergienutzung in der Bundesrepublik Deutschland 2016

    Bredberg, Ines; Hutter, Johann; Kuehn, Kerstin; Niedzwiedz, Katarzyna; Philippczyk, Frank [Bundesamt fuer kerntechnische Entsorgungssicherheit (BFE), Salzgitter (Germany); Thoemmes, Achim [Bundesamt fuer Strahlenschutz, Salzgitter (Germany)

    2017-08-15

    . Information is provided on the purpose and capacity of nuclear fuel supply and disposal facilities. The approval history and the current operating and approval status are also displayed. In the field of final disposal, the new legal structures, supervision and ongoing projects are described. The information is summarized at the end of the report in tabular form. The report is issued annually in updated form. [German] Am 30.07.2016 ist das ''Gesetz zur Neuordnung der Organisationsstruktur im Bereich der Endlagerung'' in Kraft getreten. Es sieht vor, die staatlichen Aufgaben der Genehmigung und Aufsicht im Bereich der Kerntechnik, der Zwischenlagerung, der Standortauswahl und der Endlagerueberwachung mehrheitlich in einer neuen Behoerde zu buendeln, dem Bundesamt fuer kerntechnische Entsorgungssicherheit (BfE). Mit Inkrafttreten des Gesetzes wurden die entsprechenden Fachaufgaben des Bundesamtes fuer Strahlenschutz (BfS) auf das BfE uebertragen. Die Aufgabe zur Erstellung des jaehrlichen Statusberichtes zur Kernenergienutzung ist nunmehr Aufgabe des BfE. Fuer die operativen Aufgaben der Standortsuche, der Errichtung und des Betriebs der Endlager sowie der Schachtanlage Asse II und des Bergwerks Gorleben wird eine staatseigene Gesellschaft, die Bundesgesellschaft fuer Endlagerung (BGE), die Verantwortung uebernehmen. Der vorliegende Bericht mit dem Stand 31.12.2016 gibt einen Ueberblick ueber die Nutzung der Kernenergie in der Bundesrepublik Deutschland. Im Bericht aufgefuehrt sind die wesentlichen Daten aller Kernkraftwerke, Forschungsreaktoren und der Anlagen der Kernbrennstoffver- und -entsorgung. Zum Berichtszeitpunkt 31.12.2016 waren acht Kernkraftwerksbloecke in Betrieb. Die Stromerzeugung durch Kernenergie im Jahr 2016 betrug insgesamt ca. 84,6 TWh (2015: 91,8 TWh). Der Anteil der Kernenergie an der Gesamt-Brutto-Stromerzeugung betrug 13,0 % (2015: 14,2 %). Fuer die Kernkraftwerke enthaelt der Bericht in zusammengefasster Form die wesentlichen

  2. Corrosion product deposition on fuel element surfaces of a boiling water reactor

    Orlov, A.

    2011-01-01

    Over the last decade the problem of corrosion products deposition on light water reactor fuel elements has been extensively investigated in relation to the possibility of failures caused by them. The goal of the present study is to understand in a quantitative way the formation of such kind of deposits and to analytically understand the mechanism of formation and deposition with help of the quasi-steady state concentrations of a number of 3d metals in reactor water. Recent investigations on the complex corrosion product deposits on a Boiling Water Reactor (BWR) fuel cladding have shown that the observed layer locally presents unexpected magnetic properties. The buildup of magnetic corrosion product deposits (crud) on the fuel cladding of the BWR, Kernkraftwerk Leibstadt (KKL) Switzerland has hampered the Eddy-current based measurements of ZrO 2 layer thickness. The magnetic behavior of this layer and its axial variation on BWR fuel cladding is of interest with respect to non-destructive cladding characterization. Consequently, a cladding from a BWR was cut at elevations of 810 mm, where the layer was observed to be magnetic, and of 1810 mm where it was less magnetic. The samples were subsequently analyzed using electron probe microanalysis (EPMA), magnetic analysis and X-ray techniques (μXRF, μXRD and μXAFS). Both EPMA and μXRF have shown that the observed corrosion deposit layer which is situated on the Zircaloy corrosion layer consists mostly of 3-d elements’ oxides (Fe, Zn, Ni and Mn). The distribution of these elements within the investigated layer is rather complex and not homogeneous. The main components identified by 2D μXRD mapping inside the layer were hematite and spinel phases with the common formula (M x Fe y )[M (1-x) Fe (2-y) ]O 4 , where M = Zn, Ni, Mn. With μXRD it was clearly shown that the cell parameter of analyzed spinel is different from the one of the pure endmembers (ZnFe 2 O 4 , NiFe 2 O 4 and MnFe 2 O 4 ) proving the existence of

  3. Highly specific reasons for nonadherence to antiretroviral therapy: results from the German adherence study

    Boretzki J

    2017-11-01

    Full Text Available Johanna Boretzki,1,2 Eva Wolf,3 Carmen Wiese,4 Sebastian Noe,4 Annamaria Balogh,3 Anja Meurer,5 Ivanka Krznaric,6 Alexander Zink,7 Christian Lersch,1 Christoph D Spinner1,2 1Department of Medicine II, University Hospital Klinikum rechts der Isar, Munich, 2German Center for Infection Research, Partner Site Munich, 3MUC Research, Munich, 4MVZ Karlsplatz, HIV Clinical Care Center, Munich, 5Center for Infectiology and Internal Medicine, Munich, 6Center for Infectiology Prenzlauer Berg, Berlin, 7Department of Dermatology and Allergology, University Hospital Klinikum rechts der Isar, Munich, Germany Background: Reasons for and frequency of nonadherence to antiretroviral therapy (ART may have changed due to pharmacological improvements. In addition, the importance of known non-pharmacologic reasons for nonadherence is unclear.Methods: We performed a cross-sectional, noninterventional, multicenter study to identify current reasons for nonadherence. Patients were categorized by physicians into the following adherence groups: good, unstable, or poor adherence. Co-variables of interest included age, sex, time since HIV diagnosis, ART duration, current ART regimen, HIV transmission route, comorbidity, HIV-1 RNA viral load (VL, and CD4 cell count. Patients self-reported the number of missed doses and provided their specific reasons for nonadherent behavior. Statistical analyses were performed using Fisher’s extended exact test, Kruskal–Wallis test, and logistic regression models.Results: Our study assessed 215 participants with good (n=162, unstable (n=36, and poor adherence (n=17. Compared to patients with good adherence, patients with unstable and poor adherence reported more often to have missed at least one dose during the last week (good 11% vs unstable 47% vs poor 63%, p<0.001. Physicians’ adherence assessment was concordant with patients’ self-reports of missed doses during the last week (no vs one or more in 81% cases. Similarly, we found a

  4. Causes, consequences, and therapy of the Radiophobia syndrome; Ursachen, Folgen und Therapie des Radiophobie-Syndroms

    Becker, K.

    2004-03-01

    The final storage of high-level radioactive waste, which is said to be still open while, in fact, it was solved technically a long time ago and is only being blocked for political reasons, as well as alleged technical risks of German nuclear power plants which have never been demonstrated or proven, are listed again and again as grounds for opting out of the use of nuclear power. There is hardly any doubt that one of the main causes underlying also these arguments, and thus the main reason for the insufficient public acceptance of nuclear power in Germany at the present time as a safe, inexpensive, and non-polluting source of primary energy, is the widespread fear of radiation (radiophobia). Consequently, solutions proposed for successfully managing this radiophobia must be examined. Continued scientific studies of the subject do not seem to be promising, as funds are available at present only for continuing the search for negative biological effects. Important preconditions for a change in attitude are the appropriate initiatives to be taken by the relatively small number of sufficiently independent experts of proven scientific repute. Initiatives of this kind can now be observed in numerous countries and regions in the world. It must be pointed out in this connection, as is underlined again and again by experienced experts, that risk acceptance is not a matter of factual arguments, but of emotions. Psychological and pedagogic sensitivity certainly are important elements in changing public opinion in the interest of a more realistic assessment of the radiation risk and the acceptance of nuclear power. (orig.) [German] Die angeblich noch offene, tatsaechlich aber laengst technisch geloeste und nur politisch blockierte Frage der Endlagerung hochradioaktiver Abfaelle, ebenso wie vorgebliche, tatsaechlich aber nie nachgewiesene technische Risiken der deutschen Kernkraftwerke werden immer wieder als Ausstiegsgruende fuer die Kernenergie genannt. Es bestehen kaum

  5. Environmental effects on fatigue of steels for structural parts in water-steam-circuits of light water reactors. Considerations concerning the question of transferability of results from laboratory tests to real operating conditions; Der Einfluss des Mediums auf Ermuedungsvorgaenge in Staehlen fuer Strukturbauteile in Wasser-Dampf-Kreislaeufen von Leichtwasserreaktoren. Ueberlegungen zur Frage der Uebertragbarkeit von Ergebnissen aus Laborversuchen auf den realen Anlagenbetrieb

    Roth, Armin [AREVA NP GmbH, Erlangen (Germany)

    2008-07-01

    .B. von Staehlen, beeinflussen kann. Schon vor einigen Jahrzehnten wurde experimentell nachgewiesen, dass z.B. Hochtemperaturwasser in Laborversuchen zur Untersuchung des Ermuedungsverhaltens von Staehlen zu deutlichen Effekten fuehrt. Dabei wird je nach Versuchsfuehrung entweder die Zeit bis zur Initiierung von Anrissen verkuerzt oder die Wachstumsgeschwindigkeit vorhandener Risse erhoeht. Dieser zu erwartende Einfluss des Mediums auf den Ermuedungsprozess wurde in den Anfaengen der Regulierung von Konstruktion und Auslegung von Bauteilen und Komponenten fuer Kernkraftwerke in den relevanten Regelwerken (z.B. ASME Boiler and Pressure Vessel Code, Section III) weltweit nicht explizit beruecksichtigt. Pauschal beruecksichtigt werden Umgebungseffekte dagegen in den entsprechenden da/dN-Risswachstumskurven des ASME Code, Section XI zur Bewertung des betrieblichen Verhaltens von Oberflaechenfehlern. Historisch betrachtet erfolgte in den Regelwerken die Festlegung der Vorgehensweise zur Komponentenauslegung allerdings lange vor dem gezielten experimentellen Nachweis der Umgebungseffekte auf Rissinitiierung und Risswachstum durch Ermuedung von Staehlen in Hochtemperaturwasser. Trotz dieser Erkenntnis ist es weltweit nicht zu generischen, systematischen Schaeden in Medium fuehrenden Systemen von Leichtwasserreaktoren (LWR) durch Korrosionsermuedung infolge von Fehlauslegung gekommen. Vereinzelt aufgetretene Schaeden mit deutlichen Merkmalen umgebungsbeeinflusster Ermuedungsvorgaenge konnten immer eindeutig auf das Vorkommen von unerwarteten, nicht im spezifizierten Belastungskollektiv enthaltenen Betriebstransienten zurueckgefuehrt werden. Zu diesen Ursachen zaehlen z.B. das Auftreten von thermischer Schichtung oder lokale, stroemungsinduzierte Vibrationen. In diesem Beitrag werden Ueberlegungen vorgestellt, welche die zu beobachtende Diskrepanz zwischen der diesbezueglich weltweit ueberwiegend positiven Betriebserfahrung und den Ergebnissen aus Laborversuchen mit dem

  6. Final storage of radioactive waste in Germany. Waste arisings and availability of a repository as seen by an electricity utility; Endlagerung radioaktiver Abfaelle in Deutschland. Abfallaufkommen und Endlagerverfuegbarkeit aus EVU-Sicht

    Broeskamp, H.; Brammer, K.J.; Graf, R. [Gesellschaft fuer Nuklearservice, Essen (Germany)

    2004-04-01

    The management of waste arising in the operation of nuclear power plants has been taken into account since the beginnings of the peaceful uses of nuclear power in Germany. As early as in 1957, a memorandum of the German Advisory Committee on Atomic Energy contains a reference to the need for safe disposal of radioactive waste. Legislation adopted the suggestion and laid down some provisions on the safe utilization of radioactive materials as early as in the Atomic Energy Act of December 23, 1959. In connection with the nuclear waste management center, the Federal Republic also looked for a suitable site for a repository. After thorough site selection proceedings by the federal government and the state of Lower Saxony, the Lower Saxony state government in 1977 defined Gorleben as the site. The decision has been preceded by a three-stage selection process in which more than 140 sites had been investigated. Exploration of the Gorleben site began in 1979 and was interrupted on October 1, 2000 to clarify conceptual and safety-related doubts of the federal government. The German Federal Ministry for the Environment (BMU) seeks to make a repository (for high-level waste) available in 2030. Technically, it is still possible to commission a repository for waste generating heat at Gorleben after 2025 if the salt dome is found to be suitable after speedy conclusion of the exploration work. Reference is made to foreseeable problem areas. Another project pursued by the federal government is the use of the Konrad mine as a repository for low and medium-level radioactive waste. After well over twenty years, the plans approval decision was made in May 2002 and is at present the subject of litigation. On the basis of the data presented about the expected arisings of waste generating no heat in combination with the possible start of emplacement in Konrad in 2013, detailed results are presented. (orig.) [German] Die Frage der Entsorgung der Kernkraftwerke wurde von Anfang der

  7. Foreseeable cost and economic impacts of the approach proposed; Absehbare Kosten und volkswirtschaftliche Effekte des vom AkEnd vorgeschlagenen Vorgehens

    Broeskamp, H.; Brammer, K.-J. [GNS Gesellschaft fuer Nuclear-Service mbH, Essen (Germany); Schlombs, H. [E.ON Kernkraft GmbH, Hannover (Germany)

    2003-05-01

    radioaktive Abfaelle verantwortlich. Fruehzeitig mit der Inbetriebnahme der ersten Kernkraftwerke wurden in den 1960er Jahren entsprechende Schritte eingeleitet. Diese resultierten u.a. in den Beschluessen und Auswahlverfahren der 1970er und 1980er Jahre zum Salzstock Gorleben sowie zum ehemaligen Eisenerzbergwerk Konrad als potenzielle Endlagerstandorte. Die Bundesregierung hat im Jahr 2000 fuer Gorleben ein drei- bis maximal zehnjaehriges Moratorium fuer die weiteren Erkundungsarbeiten festgelegt, um aus Sicht des Bundesministeriums fuer Umwelt, Naturschutz und Reaktorsicherheit (BMU) bestehende Zweifel abzuarbeiten. Fuer Konrad wurde im Mai 2002 ein positiver Planfeststellungsbeschluss erteilt. Nach Erlangung der Rechtssicherheit koennte ab etwa 2010-2012 die Einlagerung beginnen. Im Februar 1999 wurde der Arbeitskreis Auswahlverfahren Endlagerstandorte (AkEnd) durch das BMU berufen. Der Auftrag bestand in der Entwicklung eines nachvollziehbaren Verfahrens fuer die Suche und die Auswahl von Standorten zur Endlagerung aller Arten radioaktiver Abfaelle in Deutschland. Das vom AkEnd abschliessende vorgestellte Verfahren birgt erhebliche Unsicherheiten, u.a. bezueglich der rechtlichen Umsetzbarkeit, des erforderlichen Zeitbedarfs und der Finanzierung. Es koennen sich mit Blick auf den Salzstock Gorleben allein durch zusaetzliche Erkundungen und Verfahren Mehrkosten gegenueber der Weiterfuehrung der Projekttaetigkeiten in Hoehe von 3 bis 5 Mrd. Euro ergeben. Aehnlich hohe Mehrbelastungen - insbesondere fuer die oeffentliche Hand - sind bei einer Verzoegerung der Einlagerung in Konrad zu erwarten. Eine moeglichst zuegige Endlagerung aller Abfallarten in tiefen geologischen Formationen ist unter sicherheitstechnischen Aspekten anderen Alternativen vorzuziehen. Daher sollte unter Beruecksichtigung aller Faktoren eine weitere Erkundung von Gorleben zuegig abgeschlossen und das Projekt Konrad realisiert werden. (orig.)

  8. Single or multi-repository concept? A personal contribution to the discussion of pros and cons; Ein- oder Mehr-Endlager-Konzept? Ein persoenlicher Beitrag zur Diskussion der Vor- und Nachteile

    Closs, K.-D. [Projektraeger fuer Wassertechnologie und Entsorgung, Forschungszentrum Karlsruhe GmbH (Germany); Duphorn, K. [Christian-Albrechts-Universitaet zu Kiel (Germany); Kuehn, K. [Institut fuer Bergbau, TU Clausthal-Zellerfeld (Germany)

    2002-05-01

    Gruenen nach der Bundestagswahl von 1998 wurde zur Entsorgung der deutschen Kernkraftwerke ein von der bis dahin angestrebten Praxis abweichender Weg vereinbart. Unter anderem soll nur ein einziges Endlager in tiefen geologischen Formationen etwa ab dem Jahr 2030 zur Verfuegung stehen. Die Erkundung des Salzstockes Gorleben soll aufgrund bestehender Zweifel unterbrochen werden bei paralleler grundsaetzlicher Diskussion zu potenziell geeigneten Wirtsgesteinen und Standorten. Der von der Bundesregierung einberufene 'Arbeitskreis Auswahlverfahren Endlagerstandorte (AkEnd)' soll mit diesen Vorgaben wissenschaftliche Standortkriterien erarbeiten. Die Autoren, Mitglieder des AkEnd, kommen aufgrund von fachlichen Erkenntnissen sowie der historisch gewachsenen Entsorgungs- und Standortsituation in Deutschland zu dem Schluss, dass ein Mehr-Endlager-Konzept substanzielle Vorteile aufweist. Folgende Aspekte werden dafuer genannt: - Entsorgungskonzeption: Das Mehr-Endlager-Konzept bietet mit dem weit fortgeschrittenen Endlagerprojekt Konrad eindeutige Vorteile. Dies auch vor dem Hintergrund der von der oeffentlichen Hand zu bewaeltigenden Menge an Abfaellen mit vernachlaessigbarer Waermeentwicklung. - Langzeitsicherheit: Vorteile, u.a. im Hinblick auf sicherheitstechnische Aspekte bezueglich der moeglichen Kompromisse bei einem Ein-Endlager-Konzept und der moeglichen Einschraenkung der Anzahl potenzieller Standorte, liegen vor. - Nachweisverfahren: Es liegen nachweistechnische Vorteile bei Aufteilung der Abfaelle auf zwei oder mehr Endlager vor. - Kosten: Eine differenzierte Betrachtung der Kosten fuer alle endzulagernden Abfaelle deutet auf Vorteile - insbesondere fuer die oeffentliche Hand - bei einem Mehr-Endlager-Konzept hin. (orig.)

  9. Risk of bias and confounding of observational studies of Zika virus infection: A scoping review of research protocols.

    Reveiz, Ludovic; Haby, Michelle M; Martínez-Vega, Ruth; Pinzón-Flores, Carlos E; Elias, Vanessa; Smith, Emma; Pinart, Mariona; Broutet, Nathalie; Becerra-Posada, Francisco; Aldighieri, Sylvain; Van Kerkhove, Maria D

    2017-01-01

    Given the severity and impact of the current Zika virus (ZIKV) outbreak in the Americas, numerous countries have rushed to develop research studies to assess ZIKV and its potential health consequences. In an effort to ensure that studies are comprehensive, both internally and externally valid, and with reliable results, the World Health Organization, the Pan American Health Organization, Institut Pasteur, the networks of Fiocruz, the Consortia for the Standardization of Influenza Seroepidemiology (CONSISE) and the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) have generated six standardized clinical and epidemiological research protocols and questionnaires to address key public health questions on ZIKV. We conducted a systematic search of ongoing study protocols related to ZIKV research. We analyzed the content of protocols of 32 cohort studies and 13 case control studies for systematic bias that could produce erroneous results. Additionally we aimed to characterize the risks of bias and confounding in observational studies related to ZIKV and to propose ways to minimize them, including the use of six newly standardized research protocols. Observational studies of ZIKV face an array of challenges, including measurement of exposure and outcomes (microcephaly and Guillain-Barré Syndrome). Potential confounders need to be measured where known and controlled for in the analysis. Selection bias due to non-random selection is a significant issue, particularly in the case-control design, and losses to follow-up is equally important for the cohort design. Observational research seeking to answer key questions on the ZIKV should consider these restrictions and take precautions to minimize bias in an effort to provide reliable and valid results. Utilization of the standardized research protocols developed by the WHO, PAHO, Institut Pasteur, and CONSISE will harmonize the key methodological aspects of each study design to minimize bias at

  10. Understanding the decline and resilience loss of a long-lived social-ecological system: insights from system dynamics

    Alicia Tenza

    2017-06-01

    Full Text Available Collapse of social-ecological systems (SESs is a common process in human history. Depletion of natural resources, scarcity of human capital, or both, is/are common pathways toward collapse. We use the system dynamics approach to better understand specific problems of small-scale, long-lived SESs. We present a qualitative (or conceptual model using the conceptualization process of the system dynamics approach to study the dynamics of an oasis in Mexico that has witnessed a dramatic transition to decline in recent decades. We used indepth interviews, participant observation, expert opinions, and official statistical data sets to define the boundaries, and structure in a causal loop diagram of our studied system. We described historical trends and showed the reference mode for the main system variables (observed data, and analyzed the expected system behavior according to the system structure. We identified the main drivers that changed the system structure, as well as structural changes, and the effects of these changes on the dynamics, resilience, and vulnerability of this SES. We found that the tendency of this SES toward collapse was triggered by exogenous factors (growth of modern agriculture in nearby valleys, and socio-political relocation, and was maintained by an endogenous structure. These structural changes weakened the resilience of this SES. One of these changes resulted in a long-term maladaptation of the SES, which increased its vulnerability to frequent system disturbances (hurricanes and droughts. The conceptual model developed provides an in-depth qualitative description of the system, with an important amount of qualitative and quantitative information, to establish the structural hypothesis of the observed behavior. Using this qualitative model, the next research steps are to develop a quantitative model to test the qualitative theories, and to explore future scenarios of system resilience for decision-making processes to

  11. THE RELATION BETWEEN DRIVER BEHAVIOR AND INTELLIGENT TRANSPORT SYSTEM

    Alica Kalašová

    2017-12-01

    Full Text Available The main objective of Slovakia’s transport policy is to reduce the number of traffic accidents and increase safety on our roads. Implementation of intelligent transport systems presents one of the possibilities how to meet this goal. Acceptance of these systems by motor vehicle drivers and other road traffic participants is necessary in order for them to fulfill their purpose. Only if the drivers will accept intelligent transport systems, it is possible to flexibly and effectively manage road traffic flexibly and effectively. From the perspective of a driver it concerns, in particular, the possibility of using alternative routes when traffic accidents or other obstacles occurs on the route that would significantly affect the continuity and safety of road traffic. Thanks to these technologies, it is possible to choose the appropriate route while driving, of course based on the criterion, which the driver considers the most important during the transport from origin to destination (driving time, distance from origin to destination, fuel consumption, quality of infrastructure. Information isare provided to the driver through variable message signs or directly in the vehicle (RDS-TMC. Another advantage of intelligent transport systems is a positive impact on psychological well-being of the driver while driving. Additional information about the possible obstacles, weather conditions and dangerous situations that occur on the roads as well as alternative routes are provided to the driver well in advance. This paper is mainly focused on how the drivers perceive the influence of intelligent transport systems in Žilina region.

  12. Pharmacological characterization of BR-A-657, a highly potent nonpeptide angiotensin II receptor antagonist.

    Chi, Yong Ha; Lee, Joo Han; Kim, Je Hak; Tan, Hyun Kwang; Kim, Sang Lin; Lee, Jae Yeol; Rim, Hong-Kun; Paik, Soo Heui; Lee, Kyung-Tae

    2013-01-01

    The pharmacological profile of BR-A-657, 2-n-butyl-5-dimethylamino-thiocarbonyl-methyl-6-methyl-3-{[2-(1H-tetrazole-5-yl)biphenyl-4-yl]methyl}-pyrimidin-4(3H)-one, a new nonpeptide AT1-selective angiotensin receptor antagonist, has been investigated in a variety of in vitro and in vivo experimental models. In the present study, BR-A-657 displaced [(125)I][Sar(1)-Ile(8)]angiotensin II (Ang II) from its specific binding sites to AT1 subtype receptors in membrane fractions of HEK-293 cells with an IC50 of 0.16 nM. In a functional assay using isolated rabbit thoracic aorta, BR-A-657 inhibited the contractile response to Ang II (pD'2: 9.15) with a significant reduction in the maximum. In conscious rats, BR-A-657 (0.01, 0.1, 1 mg/kg; intravenously (i.v.)) dose-dependently antagonized Ang II-induced pressor responses. In addition, BR-A-657 dose-dependently decreased mean arterial pressure in furosemide-treated rats and renal hypertensive rats. Moreover, BR-A-657 given orally at 1 and 3 mg/kg reduced blood pressure in conscious renal hypertensive rats. Taken together, these findings indicate that BR-A-657 is a potent and specific antagonist of Ang II at the AT1 receptor subtype, and reveal the molecular basis responsible for the marked lowering of blood pressure in conscious rats.

  13. ON THE FORMATION AND ISOMER SPECIFIC DETECTION OF PROPENAL (C{sub 2}H{sub 3}CHO) AND CYCLOPROPANONE (c-C{sub 3}H{sub 4}O) IN INTERSTELLAR MODEL ICES—A COMBINED FTIR AND REFLECTRON TIME-OF-FLIGHT MASS SPECTROSCOPIC STUDY

    Abplanalp, Matthew J.; Borsuk, Aleca; Jones, Brant M.; Kaiser, Ralf I., E-mail: ralfk@hawaii.edu [W. M. Keck Research Laboratory in Astrochemistry, University of Hawaii at Manoa, Honolulu, Hawaii, HI, 96822 (United States)

    2015-11-20

    The formation routes of two structural isomers—propenal (C{sub 2}H{sub 3}CHO) and cyclopropanone (c-C{sub 3}H{sub 4}O)—were investigated experimentally by exposing ices of astrophysical interest to energetic electrons at 5.5 K thus mimicking the interaction of ionizing radiation with interstellar ices in cold molecular clouds. The radiation-induced processing of these ices was monitored online and in situ via Fourier Transform Infrared spectroscopy and via temperature programmed desorption exploiting highly sensitive reflectron time-of-flight mass spectrometry coupled with single photon ionization in the post irradiation phase. To selectively probe which isomer(s) is/are formed, the photoionization experiments were conducted with 10.49 and 9.60 eV photons. Our studies provided compelling evidence on the formation of both isomers—propenal (C{sub 2}H{sub 3}CHO) and cyclopropanone (c-C{sub 3}H{sub 4}O)—in ethylene (C{sub 2}H{sub 4})—carbon monoxide (CO) ices forming propenal and cyclopropanone at a ratio of (4.5 ± 0.9):1. Based on the extracted reaction pathways, the cyclopropanone molecule can be classified as a tracer of a low temperature non-equilibrium chemistry within interstellar ices involving most likely excited triplet states, whereas propenal can be formed at ultralow temperatures, but also during the annealing phase via non-equilibrium as well as thermal chemistry (radical recombination). Since propenal has been detected in the interstellar medium and our laboratory experiments demonstrate that both isomers originated from identical precursor molecules our study predicts that the hitherto elusive second isomer—cyclopropanone—should also be observable toward those astronomical sources such as Sgr B2(N) in which propenal has been detected.

  14. The osteo-inductive activity of bone-marrow-derived mononuclear cells resides within the CD14+ population and is independent of the CD34+ population.

    Henrich, D; Seebach, C; Verboket, R; Schaible, A; Marzi, I; Bonig, H

    2018-03-06

    Bone marrow mononuclear cells (BMC) seeded on a scaffold of β-tricalcium phosphate (β-TCP) promote bone healing in a critical-size femur defect model. Being BMC a mixed population of predominantly mature haematopoietic cells, which cell type(s) is(are) instrumental for healing remains elusive. Although clinical therapies using BMC are often dubbed as stem cell therapies, whether stem cells are relevant for the therapeutic effects is unclear and, at least in the context of bone repair, seems dubious. Instead, in light of the critical contribution of monocytes and macrophages to tissue development, homeostasis and injury repair, in the current study it was hypothesised that BMC-mediated bone healing derived from the stem cell population. To test this hypothesis, bone remodelling studies were performed in an established athymic rats critical-size femoral defect model, with β-TCP scaffolds augmented with complete BMC or BMC immunomagnetically depleted of stem cells (CD34+) or monocytes/macrophages (CD14+). Bone healing was assessed 8 weeks after transplantation. Compared to BMC-augmented controls, when CD14- BMC, but not CD34- BMC were transplanted into the bone defect, femora possessed dramatically decreased biomechanical stability and new bone formation was markedly reduced, as measured by histology. The degree of vascularisation did not differ between the two groups. It was concluded that the monocyte fraction within the BMC provided critical osteo-inductive cues during fracture healing. Which factors were responsible at the molecular levels remained elusive. However, this study marked a significant progress towards elucidating the mechanisms by which BMC elicit their therapeutic effects, at least in bone regeneration.

  15. Introduce of Viable But Nonculturable Bacteria

    Mehdi Hassanshahian

    2008-03-01

    Full Text Available Viable-But-Nonculturable-State (VBNC is the condition in which bacteria fail to grow on their routine bacteriological media where they would normally grow and develop into colonies, but are still alive and capable of renewed metabolic activity. VBNC state is useful for evaluating public health and for ascertaining the sterility of drinking water, pharmaceuticals, and foodstuff. A number of bacteria, mostly pathogenic to humans, have been proved to enter into this state in response to natural stresses such as starvation, incubation out of optimum growth temperature, increased osmotic pressure, etc. Once in the VBNC state, they undergo various physiological, structural, and genetic alterations. These alterations result in reduced cell size, conversion from bacilli to coccid, thickened cell walls, and peptidoglycan gaining many cross links. Metabolic changes also occur that include reductions in growth, nutrient transport, and respiratory rate; biosynthesis of new protein, and ATP remaining at a constant level. It has been shown that in the VBNC state, some pathogens conserve their virulence properties. Gene expression continues in the VBNC cell. Nucleic acids remain intact in the early VBNC phase but they gradually undergo degradation with prolonged VBNC. Cytological methods such as direct viable count and reduction of tetrazolium salts, and molecular methods such as reverse transcription polymerase chain reaction and green fluorescent protein have been used for the study of VBNC. Resuscitation from VBNC state starts when the inducing factor(s is/are lifted. Factors that help the resuscitation of VBNC bacteria include addition of certain nutrients and chemicals, introduction of a few culturable cells into the VBNC cell population, and passage through the animal host. As virulence properties are sustained during the VBNC phase, special care must be paid when evaluating sterility of drinking water.

  16. Annual meeting on nuclear technology. Opening address

    Gueldner, Ralf [DAtF, Berlin (Germany)

    2014-07-15

    The operators of Germany's nuclear power plants continue to make their contribution to the security of supply with the safe and reliable operation of their plants, thus ensuring the success of the energy transition. Despite increased load following operation due to a further increase in feed-in especially of volatile renewable energies, three German nuclear power plants were in the Top Ten global producers of electricity from nuclear energy in 2013. In spite of not producing an equivalent of seven full-load days due to load following operation, the Isar 2 nuclear power plant once again bears the proud title of 'world champion producer'. This balance is also an impressive performance record for nuclear power made in Germany. Despite the accelerated nuclear phase-out, German plants with German operators, and suppliers and service providers based mainly in Germany, are in the top category worldwide once more. Since the end of last year Germany has a new Federal Government as a new version of the grand coalition of 2005 to 2009. The government has set new priorities in the energy sector. However, on many questions concerning nuclear energy, particularly the complex topics of decommissioning and waste management, we are still seeing far too little movement at present. Main topics are: - New site selection process for final repository for high active waste, - Alternative interim storage - just not Gorleben, - Decommissioning, dismantling and administrative bottlenecks, - Lack of predictability for low and medium active waste, - Nuclear fuel tax, electricity market and security of supply, - Electricity market, security of supply and regulation. (orig.)

  17. Meniscectomy: indications, procedure, outcomes, and rehabilitation

    Anetzberger H

    2013-12-01

    Full Text Available Hermann Anetzberger,1 Christof Birkenmaier,2 Stephan Lorenz3 1Orthopädische Gemeinschaftspraxis am OEZ, Munich, Germany; 2Department of Orthopedics, Ludwig-Maximilian-University Munich, Munich, Germany; 3Department of Orthopedic Sports Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany Abstract: Meniscal injuries are among the most frequent reasons for knee problems. The goal of this manuscript is to review the biomechanical relevance of the human knee's menisci in relation to surgical indications, surgical techniques, rehabilitation, and outcomes. In order to identify the relevant literature, we performed a PubMed search for the years ranging from 1980–2013 using the following search terms: meniscus; biomechanical function; meniscectomy; meniscal repair; and clinical outcome. The meniscus helps to distribute the forces between the tibial and femoral articular cartilage layers in a load-sharing capacity. Meniscus damage or meniscectomy intuitively leads to an overloading of the cartilage and, hence, to the development of osteoarthrosis. Precise knowledge of meniscal shape and function, of the type of injury, of surgical techniques, as well as of postsurgical rehabilitative care are of decisive importance for an individually-adjusted treatment strategy. Other underlying coexisting knee pathologies also need to be considered. The diagnosis of a meniscal injury is based upon clinical history, physical examination, and imaging studies. The treatment of a meniscal lesion includes conservative, as well as operative, procedures. The goals of surgery are to reduce pain and disability, as well as to preserve meniscal function without causing additional cartilage damage. The resection of meniscal tissue should be restricted to as much as is necessary, and as little as is reasonably possible. Postoperative rehabilitation serves the purpose of improving functional deficits and pain, as well as of restoring a good range of

  18. Experimental Research on Dreaming: State of the Art and Neuropsychoanalytic Perspectives

    Ruby, Perrine M.

    2011-01-01

    Dreaming is still a mystery of human cognition, although it has been studied experimentally for more than a century. Experimental psychology first investigated dream content and frequency. The neuroscientific approach to dreaming arose at the end of the 1950s and soon proposed a physiological substrate of dreaming: rapid eye movement sleep. Fifty years later, this hypothesis was challenged because it could not explain all of the characteristics of dream reports. Therefore, the neurophysiological correlates of dreaming are still unclear, and many questions remain unresolved. Do the representations that constitute the dream emerge randomly from the brain, or do they surface according to certain parameters? Is the organization of the dream’s representations chaotic or is it determined by rules? Does dreaming have a meaning? What is/are the function(s) of dreaming? Psychoanalysis provides hypotheses to address these questions. Until now, these hypotheses have received minimal attention in cognitive neuroscience, but the recent development of neuropsychoanalysis brings new hopes of interaction between the two fields. Considering the psychoanalytical perspective in cognitive neuroscience would provide new directions and leads for dream research and would help to achieve a comprehensive understanding of dreaming. Notably, several subjective issues at the core of the psychoanalytic approach, such as the concept of personal meaning, the concept of unconscious episodic memory and the subject’s history, are not addressed or considered in cognitive neuroscience. This paper argues that the focus on singularity and personal meaning in psychoanalysis is needed to successfully address these issues in cognitive neuroscience and to progress in the understanding of dreaming and the psyche. PMID:22121353

  19. TCDD and a putative endogenous AhR ligand, ITE, elicit the same immediate changes in gene expression in mouse lung fibroblasts.

    Henry, Ellen C; Welle, Stephen L; Gasiewicz, Thomas A

    2010-03-01

    The aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor, mediates toxicity of several classes of xenobiotics and also has important physiological roles in differentiation, reproduction, and immunity, although the endogenous ligand(s) mediating these functions is/are as yet unidentified. One candidate endogenous ligand, 2-(1'H-indolo-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE), is a potent AhR agonist in vitro, activates the murine AhR in vivo, but does not induce toxicity. We hypothesized that ITE and the toxic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), may modify transcription of different sets of genes to account for their different toxicity. To test this hypothesis, primary mouse lung fibroblasts were exposed to 0.5muM ITE, 0.2nM TCDD, or vehicle for 4 h, and total gene expression was evaluated using microarrays. After this short-term and low-dose treatment, several hundred genes were changed significantly, and the response to ITE and TCDD was remarkably similar, both qualitatively and quantitatively. Induced gene sets included the expected battery of AhR-dependent xenobiotic-metabolizing enzymes, as well as several sets that reflect the inflammatory role of lung fibroblasts. Real time quantitative RT-qPCR assay of several selected genes confirmed these microarray data and further suggested that there may be kinetic differences in expression between ligands. These data suggest that ITE and TCDD elicit an analogous change in AhR conformation such that the initial transcription response is the same. Furthermore, if the difference in toxicity between TCDD and ITE is mediated by differences in gene expression, then it is likely that secondary changes enabled by the persistent TCDD, but not by the shorter lived ITE, are responsible.

  20. Macro-localization study of a commercial CAREM nuclear power plant in the province of Formosa : state of progress

    Torino Araoz, Ines

    2011-01-01

    The framework agreement signed between Formosa Province and the National Atomic Energy Commission (CNEA) in order to establish formal relations of cooperation with regard to projects of common interest, research and development, technology services, human resource training in the areas inherent to CNEA functions, resulted in a specific agreement in order to analyze the potential location of a CAREM commercial nuclear power plant in the Province. Thus, the site survey study which is under development aims at the determination of one or more sites, which meet the criteria set - security related and not related - and is/are eligible for the installation of the plant. The site selection methodology used to develop the study was based on documentation and bibliography of the International Atomic Energy Agency and CNEA. Taking into account these references, the study began divided into 3 levels; currently, Level I is approved and the analysis of Level II is completed. Each of these levels covers different aspects that must be evaluated during the selection process. That one is a complex analysis, which was carried out through the participation and joint efforts of a multidisciplinary team consisting of CNEA’s staff and the Province of Formosa, which in turn had the cooperation of various institutions. Partial results of the Level II document, determine the pre selection of three potential areas in the province. In turn, it is important to remember that the site survey (regional) study is the first stage in the selection process. Then, the site evaluation stage (micro siting study) and the preparation of the Preliminary Safety Report have to be implemented, in order to establish the definitive site for the plant installation. (author) [es

  1. A LAST LOOK AT THE MICROWAVE HAZE/BUBBLES WITH WMAP

    Dobler, Gregory, E-mail: dobler@kitp.ucsb.edu [Kavli Institute for Theoretical Physics, University of California, Santa Barbara Kohn Hall, Santa Barbara, CA 93106 (United States)

    2012-05-01

    The microwave 'haze' was first discovered with the initial release of the full sky data from the Wilkinson Microwave Anisotropy Probe (WMAP). It is diffuse emission toward the center of our Galaxy with spectral behavior that makes it difficult to categorize as any of the previously known emission mechanisms at those wavelengths. With now seven years of WMAP data publicly available, we have learned much about the nature of the haze, and with the release of data from the Fermi Gamma-Ray Space Telescope and the discovery of the gamma-ray haze/bubbles, we have had a spectacular confirmation of its existence at other wavelengths. As the WMAP mission winds down and the Planck mission prepares to release data, I take a last look at what WMAP has to tell us about the origin of this unique Galactic feature. Much like the gamma rays, the microwave haze/bubbles is/are elongated in latitude with respect to longitude by a factor of roughly two, and at high latitudes, the microwave emission cuts off sharply above {approx}35 Degree-Sign (compared to {approx}50 Degree-Sign in the gammas). The hard spectrum of electrons required to generate the microwave synchrotron is consistent with that required to generate gamma-ray emission via inverse Compton scattering, though it is likely that these signals result from distinct regions of the spectrum ({approx}10 GeV for the microwaves and {approx}1 TeV for the gammas). While there is no evidence for significant haze polarization in the seven-year WMAP data, I demonstrate explicitly that it is unlikely such a signal would be detectable above the noise.

  2. Improved measurements of mean sea surface velocity in the Nordic Seas from synthetic aperture radar

    Wergeland Hansen, Morten; Johnsen, Harald; Engen, Geir; Øie Nilsen, Jan Even

    2017-04-01

    The warm and saline surface Atlantic Water (AW) flowing into the Nordic Seas across the Greenland-Scotland ridge transports heat into the Arctic, maintaining the ice-free oceans and regulating sea-ice extent. The AW influences the region's relatively mild climate and is the northern branch of the global thermohaline overturning circulation. Heat loss in the Norwegian Sea is key for both heat transport and deep water formation. In general, the ocean currents in the Nordic Seas and the North Atlantic Ocean is a complex system of topographically steered barotropic and baroclinic currents of which the wind stress and its variability is a driver of major importance. The synthetic aperture radar (SAR) Doppler centroid shift has been demonstrated to contain geophysical information about sea surface wind, waves and current at an accuracy of 5 Hz and pixel spacing of 3.5 - 9 × 8 km2. This corresponds to a horizontal surface velocity of about 20 cm/s at 35° incidence angle. The ESA Prodex ISAR project aims to implement new and improved SAR Doppler shift processing routines to enable reprocessing of the wide swath acquisitions available from the Envisat ASAR archive (2002-2012) at higher resolution and better accuracy than previously obtained, allowing combined use with Sentinel-1 and Radarsat-2 retrievals to build timeseries of the sea surface velocity in the Nordic Seas. Estimation of the geophysical Doppler shift from new SAR Doppler centroid shift retrievals will be demonstrated, addressing key issues relating to geometric (satellite orbit and attitude) and electronic (antenna mis-pointing) contributions and corrections. Geophysical Doppler shift retrievals from one month of data in January 2010 and the inverted surface velocity in the Nordic Seas are then addressed and compared to other direct and indirect estimates of the upper ocean current, in particular those obtained in the ESA GlobCurrent project.

  3. Underuse of Anticoagulation in Older Patients with Atrial Fibrillation and CHADS2 Score ≥ 2: Are We Doing Better Since the Marketing of Direct Oral Anticoagulants?

    Henrard, Séverine; Vandenabeele, Caroline; Marien, Sophie; Boland, Benoit; Dalleur, Olivia

    2017-11-01

    Our objectives were to (1) describe the evolution of the underuse of anticoagulants in older people with atrial fibrillation (AF) and a CHADS 2 score ≥ 2 since direct oral anticoagulants (DOACs) were introduced to the market and (2) describe factors associated with this underuse. We conducted a retrospective cross-sectional study including geriatric patients admitted during the pre-DOAC (2008-2011) and post-DOAC (2013-2015) periods in an academic hospital in Belgium. Five inclusion criteria were met: age ≥ 75 years, diagnosis of AF, indication for anticoagulation (CHADS 2 score ≥ 2), risk of functional decline (Identification of Seniors At Risk [ISAR] score ≥ 2), and comprehensive geriatric assessment. The use of anticoagulants and antiplatelets at home before admission was recorded. Risks of stroke and bleeding were calculated using CHADS 2 and HEMORR 2 HAGES scores, respectively. Three different logistic regression models were performed to describe the evolution of and factors associated with the underuse of anticoagulants after DOAC marketing. Anticoagulant underuse, present in 209 of 614 (34%) geriatric patients with AF, was lower in patients with a history of stroke (28.5%) or congestive heart failure (26.9%) but higher in those receiving antiplatelets (56.2%) and in older individuals. Anticoagulant underuse decreased significantly from the pre-DOAC (37.3%) to the post-DOAC (29.7%) era, as shown by two analyses using propensity scores. In older patients with AF, anticoagulant underuse was mainly associated with antiplatelet use. Anticoagulant underuse and antiplatelet use have both decreased since DOAC marketing. Underuse of anticoagulants was still a concern for three in ten geriatric patients with AF at high risk of stroke (CHADS 2 score ≥ 2).

  4. Risk of bias and confounding of observational studies of Zika virus infection: A scoping review of research protocols.

    Ludovic Reveiz

    Full Text Available Given the severity and impact of the current Zika virus (ZIKV outbreak in the Americas, numerous countries have rushed to develop research studies to assess ZIKV and its potential health consequences. In an effort to ensure that studies are comprehensive, both internally and externally valid, and with reliable results, the World Health Organization, the Pan American Health Organization, Institut Pasteur, the networks of Fiocruz, the Consortia for the Standardization of Influenza Seroepidemiology (CONSISE and the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC have generated six standardized clinical and epidemiological research protocols and questionnaires to address key public health questions on ZIKV.We conducted a systematic search of ongoing study protocols related to ZIKV research. We analyzed the content of protocols of 32 cohort studies and 13 case control studies for systematic bias that could produce erroneous results. Additionally we aimed to characterize the risks of bias and confounding in observational studies related to ZIKV and to propose ways to minimize them, including the use of six newly standardized research protocols.Observational studies of ZIKV face an array of challenges, including measurement of exposure and outcomes (microcephaly and Guillain-Barré Syndrome. Potential confounders need to be measured where known and controlled for in the analysis. Selection bias due to non-random selection is a significant issue, particularly in the case-control design, and losses to follow-up is equally important for the cohort design.Observational research seeking to answer key questions on the ZIKV should consider these restrictions and take precautions to minimize bias in an effort to provide reliable and valid results. Utilization of the standardized research protocols developed by the WHO, PAHO, Institut Pasteur, and CONSISE will harmonize the key methodological aspects of each study design to

  5. Demand for integrative medicine among women in pregnancy and childbed: a German survey on patients' needs.

    Schürger, Nikolas; Klein, Evelyn; Hapfelmeier, Alexander; Kiechle, Marion; Paepke, Daniela

    2018-06-15

    Although integrative medicine is gaining increasing attention and is claiming more and more its place in modern health care, it still plays a marginal role in conventional maternity care. The present study aims to examine the patterns of Complementary and Alternative Medicine (CAM) use and the demand for integrative therapies, including CAM, relaxation therapies, nutritional counseling, and psychological assistance, among women in pregnancy and childbed. The survey was conducted from April 2017 to July 2017 by means of a pseudo-anonymous 38-item questionnaire at the Department of Gynecology and Obstetrics, Klinikum rechts der Isar, Technical University of Munich. Eligible participants were women hospitalized due to pregnancy related complications and women in childbed. Descriptive statistics were generated to determine patterns of CAM use and demand for integrative therapeutic approaches. Univariate analysis was used to detect associations between patients' characteristics and their interest in the different integrative therapies. Furthermore, binary logistic regression was used to estimate the odds ratio of demand for CAM. A total of 394 out of 503 patients participated in the survey (78%). 60% declared using CAM in general, 45% specifically in relation to their pregnancy or childbed. Most commonly used modalities were vitamins (31% of all patients), yoga (24%), and herbal supplements (23%). Most popular sources of recommendation of CAM use were midwives and gynecologists. Integrative therapy options patients would have wanted alongside conventional maternity care were CAM (64%), relaxation therapies (44%), dietary counseling (28%), and psychological counseling (15%). Furthermore, associations between patients' sociodemographic characteristics and their demand for integrative therapies were identified. The results of this study demonstrate that there is a considerable demand for integrative medicine and widespread use of CAM among women during pregnancy and

  6. SAR image dataset of military ground targets with multiple poses for ATR

    Belloni, Carole; Balleri, Alessio; Aouf, Nabil; Merlet, Thomas; Le Caillec, Jean-Marc

    2017-10-01

    Automatic Target Recognition (ATR) is the task of automatically detecting and classifying targets. Recognition using Synthetic Aperture Radar (SAR) images is interesting because SAR images can be acquired at night and under any weather conditions, whereas optical sensors operating in the visible band do not have this capability. Existing SAR ATR algorithms have mostly been evaluated using the MSTAR dataset.1 The problem with the MSTAR is that some of the proposed ATR methods have shown good classification performance even when targets were hidden,2 suggesting the presence of a bias in the dataset. Evaluations of SAR ATR techniques are currently challenging due to the lack of publicly available data in the SAR domain. In this paper, we present a high resolution SAR dataset consisting of images of a set of ground military target models taken at various aspect angles, The dataset can be used for a fair evaluation and comparison of SAR ATR algorithms. We applied the Inverse Synthetic Aperture Radar (ISAR) technique to echoes from targets rotating on a turntable and illuminated with a stepped frequency waveform. The targets in the database consist of four variants of two 1.7m-long models of T-64 and T-72 tanks. The gun, the turret position and the depression angle are varied to form 26 different sequences of images. The emitted signal spanned the frequency range from 13 GHz to 18 GHz to achieve a bandwidth of 5 GHz sampled with 4001 frequency points. The resolution obtained with respect to the size of the model targets is comparable to typical values obtained using SAR airborne systems. Single polarized images (Horizontal-Horizontal) are generated using the backprojection algorithm.3 A total of 1480 images are produced using a 20° integration angle. The images in the dataset are organized in a suggested training and testing set to facilitate a standard evaluation of SAR ATR algorithms.

  7. Piano training in youths with hand motor impairments after damage to the developing brain

    Lampe R

    2015-08-01

    Full Text Available Renée Lampe,1,* Anna Thienel,2 Jürgen Mitternacht,1 Tobias Blumenstein,1 Varvara Turova,1 Ana Alves-Pinto1,* 1Research Unit for Paediatric Neuroorthopaedics and Cerebral Palsy, Orthopaedics Department, Klinikum Rechts der Isar, Technische Universität München, 2Department Sonderpädagogik, Ludwig Maximilians-Universität München, Munich, Germany *These authors contributed equally to this work Abstract: Damage to the developing brain may lead to impairment of the hand motor function and negatively impact on patients’ quality of life. Development of manual dexterity and finger and hand motor function may be promoted by learning to play the piano. The latter brings together music with the intensive training of hand coordination and fine finger mobility. We investigated if learning to play the piano helped to improve hand motor skills in 18 youths with hand motor disorders resulting from damage during early brain development. Participants trained 35–40 minutes twice a week for 18 months with a professional piano teacher. With the use of a Musical Instrument Digital Interface piano, the uniformity of finger strokes could be objectively assessed from the timing of keystrokes. The analysis showed a significant improvement in the uniformity of keystrokes during the training. Furthermore, the youths showed strong motivation and engagement during the study. This is nevertheless an open study, and further studies remain needed to exclude effects of growth and concomitant therapies on the improvements observed and clarify which patients will more likely benefit from learning to play the piano. Keywords: manual skill, cerebral palsy, neurodevelopmental disorder, music, rehabilitation

  8. The clinical picture of cachexia: a mosaic of different parameters (experience of 503 patients).

    Schwarz, S; Prokopchuk, O; Esefeld, K; Gröschel, S; Bachmann, J; Lorenzen, S; Friess, H; Halle, M; Martignoni, M E

    2017-02-14

    Despite our growing knowledge about the pathomechanisms of cancer cachexia, a whole clinical picture of the cachectic patient is still missing. Our objective was to evaluate the clinical characteristics in cancer patients with and without cachexia to get the whole picture of a cachectic patient. Cancer patients of the University Clinic "Klinikum rechts der Isar" with gastrointestinal, gynecological, hematopoietic, lung and some other tumors were offered the possibility to take part in the treatment concept including a nutrition intervention and an individual training program according to their capability. We now report on the first 503 patients at the time of inclusion in the program between March 2011 and October 2015. We described clinical characteristics such as physical activity, quality of life, clinical dates and food intake. Of 503 patients with cancer, 131 patients (26.0%) were identified as cachectic, 369 (73.4%) as non-cachectic. The change in cachexia were 23% reduced capacity performance (108 Watt for non-cachectic-patients and 83 Watt for cachectic patients) and 12% reduced relative performance (1.53 Watt/kg for non-cachectic and 1.34 Watt/kg for cachectic patients) in ergometry test. 75.6% of non-cachectic and 54.3% of cachectic patients still received curative treatment. Cancer cachectic patients have multiple symptoms such as anemia, impaired kidney function and impaired liver function with elements of mild cholestasis, lower performance and a poorer quality of life in the EORTC questionnaire. Our study reveals biochemical and clinical specific features of cancer cachectic patients.

  9. In situ analysis of thin film deposition processes using time-of-flight (TOF) ion beam analysis methods

    Im, J.; Lin, Y.; Schultz, J.A.; Auciello, O.H.; Chang, R.P.H.

    1995-05-01

    Non-destructive, in situ methods for characterization of thin film growth phenomena is key to understand thin film growth processes and to develop more reliable deposition procedures, especially for complex layered structures involving multi-phase materials. However, surface characterization methods that use either electrons (e.g. AES or XPS) or low energy ions (SIMS) require an UHV environment and utilize instrumentation which obstructs line of sight access to the substrate and are therefore incompatible with line of sight deposition methods and thin film deposition processes which introduce gas, either part of the deposition or in order to produce the desired phase. We have developed a means of differentially pumping both the ion beam source and detectors of a TOF ion beam surface analysis spectrometer that does not interfere with the deposition process and permits compositional and structural analysis of the growing film in the present system, at pressures up to several mTorr. Higher pressures are feasible with modified source-detector geometry. In order to quantify the sensitivity of Ion Scattering Spectroscopy (ISS) and Direct Recoil Spectroscopy (DRS), we have measured the signal intensity for stabilized clean metals in a variety of gas environments as a function of the ambient gas species and pressure, and ion beam species and kinetic energy. Results are interpreted in terms of collision cross sections which are compared with known gas phase scattering data and provide an apriori basis for the evaluation of time-of-flight ion scattering and recoil spectroscopies (ToF-ISARS) for various industrial processing environments which involve both inert and reactive cases. The cross section data for primary ion-gas molecule and recoiled atom-gas molecule interactions are also provided. from which the maximum operating pressure in any experimental configuration can be obtained

  10. Comprehensive geriatric assessment, multifactorial interventions and nurse-led care coordination to prevent functional decline in community-dwelling older persons: protocol of a cluster randomized trial

    Suijker Jacqueline J

    2012-04-01

    Full Text Available Abstract Background Functional decline in community-dwelling older persons is associated with the loss of independence, the need for hospital and nursing-home care and premature death. The effectiveness of multifactorial interventions in preventing functional decline remains controversial. The aim of this study is to investigate whether functional decline in community-dwelling older persons can be delayed or prevented by a comprehensive geriatric assessment, multifactorial interventions and nurse-led care coordination. Methods/Design In a cluster randomized controlled trial, with the general practice as the unit of randomization, 1281 participants from 25 general practices will be enrolled in each condition to compare the intervention with usual care. The intervention will focus on older persons who are at increased risk for functional decline, identified by an Identification of Seniors at Risk Primary Care (ISAR-PC score (≥ 2. These older persons will receive a comprehensive geriatric assessment, an individually tailored care and treatment plan, consisting of multifactorial, evidence-based interventions and subsequent nurse-led care coordination. The control group will receive 'care as usual' by the general practitioner (GP. The main outcome after 12 months is the level of physical functioning on the modified Katz-15 index score. The secondary outcomes are health-related quality of life, psychological and social functioning, healthcare utilization and institutionalization. Furthermore, a process evaluation and cost-effectiveness analysis will be performed. Discussion This study will provide new knowledge regarding the effectiveness and feasibility of a comprehensive geriatric assessment, multifactorial interventions and nurse-led elderly care in general practice. Trial registration NTR2653 Grant Unrestricted grant 'The Netherlands Organisation for Health Research and development' no 313020201

  11. Imaging of Hsp70-positive tumors with cmHsp70.1 antibody-conjugated gold nanoparticles

    Gehrmann MK

    2015-09-01

    Full Text Available Mathias K Gehrmann,1 Melanie A Kimm,2 Stefan Stangl,1 Thomas E Schmid,1 Peter B Noël,2 Ernst J Rummeny,2 Gabriele Multhoff11Department of Radiation Oncology, 2Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Munich, GermanyAbstract: Real-time imaging of small tumors is still one of the challenges in cancer diagnosis, prognosis, and monitoring of clinical outcome. Targeting novel biomarkers that are selectively expressed on a large variety of different tumors but not normal cells has the potential to improve the imaging capacity of existing methods such as computed tomography. Herein, we present a novel technique using cmHsp70.1 monoclonal antibody-conjugated spherical gold nanoparticles for quantification of the targeted uptake of gold nanoparticles into membrane Hsp70-positive tumor cells. Upon binding, cmHsp70.1-conjugated gold nanoparticles but not nanoparticles coupled to an isotype-matched IgG1 antibody or empty nanoparticles are rapidly taken up by highly malignant Hsp70 membrane-positive mouse tumor cells. After 24 hours, the cmHsp70.1-conjugated gold nanoparticles are found to be enriched in the perinuclear region. Specificity for membrane Hsp70 was shown by using an Hsp70 knockout tumor cell system. Toxic side effects of the cmHsp70.1-conjugated nanoparticles are not observed at a concentration of 1–10 µg/mL. Experiments are ongoing to evaluate whether cmHsp70.1 antibody-conjugated gold nanoparticles are suitable for the detection of membrane-Hsp70-positive tumors in vivo.Keywords: heat shock protein 70, tumor biomarker, theranostics, multimodal CT, multispectral CT, k-edge

  12. Minding the Gap: Marxian Reflections on the Transition from Capitalism to Postcapitalism

    Bryant William Sculos

    2018-05-01

    postcapitalist transformation? (3 What is/are the role(s of revolutionaries in dealing with the first two questions?

  13. Imaging of concrete specimens using inverse synthetic aperture radar

    Rhim, Hong C.; Buyukozturk, Oral

    2000-01-01

    Radar Measurement results of laboratory size concrete specimens are presented in this paper. The purpose of this research work is to study various aspects of the radar method in an effort to develop an improved radar system for nondestructive testing of concrete structures. The radar system used for the study is an Inverse Synthetic Aperture Radar (ISAR), which is capable of transmitting microwaves at three different frequency ranges of 2-3.4, 3.4-5.8, and 8-12 GHz. Radar measurement setup is such that the radar is locates 14.4 m away from a concrete target to satisfy a far-field criterion. The concrete target is rotated for 20 degrees during the measurements for the generation of two-dimensional (cross-range) imagery. Concrete targets used for the measurements have the dimensions of 305 mm (width)x305 mm (height)x92 mm (thickness) with different inside configurations. Comparisons are made for dry and wet specimens, specimens with and without inclusions. Each specimen is made to model various situations that a concrete structure can have in reality. Results show that center frequency, frequency bandwidth, and polarization of the incident wave have different effects on identifying the thickness or inclusions inside concrete specimens. Results also suggest that a certain combination of measurement parameters is suitable for a specific application area. Thus, measurement parameters can be optimized for a specific problem. The findings are presented and discussed in details in the paper. Signal processing schemes implemented for imaging of the specimens are also discussed

  14. XIAP reverses various functional activities of FRNK in endothelial cells

    Ahn, Sunyoung; Kim, Hyun Jeong; Chi, Sung-Gil; Park, Heonyong

    2012-01-01

    Highlights: ► FRNK domain is recruited into focal adhesion (FA), controlling endothelial cell adhesion. ► XIAP binds the FRNK domain of FAK. ► XIAP inhibits recruitment of FRNK into Fas and FRNK-promoted cell adhesion. ► XIAP plays a key role in vascular functions of FRNK or FRNK domain-mediated vascular functions of FAK. -- Abstract: In endothelial cells, focal adhesion kinase (FAK) regulates cell proliferation, migration, adhesion, and shear-stimulated activation of MAPK. We recently found that FAK is recruited into focal adhesion (FA) sites through interactions with XIAP (X-chromosome linked inhibitor of apoptosis protein) and activated by Src kinase in response to shear stress. In this study, we examined which domain(s) of FAK is(are) important for various vascular functions such as FA recruiting, XIAP-binding and shear stress-stimulated ERK activation. Through a series of experiments, we determined that the FRNK domain is recruited into FA sites and promotes endothelial cell adhesion. Interestingly, XIAP knockdown was shown to reduce FA recruitment of FRNK and the cell adhesive effect of FRNK. In addition, we found that XIAP interacts with FRNK, suggesting cross-talk between XIAP and FRNK. We also demonstrated that FRNK inhibits endothelial cell migration and shear-stimulated ERK activation. These inhibitory effects of FRNK were reversed by XIAP knockdown. Taken together, we can conclude that XIAP plays a key role in vascular functions of FRNK or FRNK domain-mediated vascular functions of FAK.

  15. Principal Component Analysis to Explore Climatic Variability and Dengue Outbreak in Lahore

    Syed Afrozuddin Ahmed

    2014-08-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE Various studies have reported that global warming causes unstable climate and many serious impact to physical environment and public health. The increasing incidence of dengue incidence is now a priority health issue and become a health burden of Pakistan.  In this study it has been investigated that spatial pattern of environment causes the emergence or increasing rate of dengue fever incidence that effects the population and its health. Principal component analysis is performed for the purpose of finding if there is/are any general environmental factor/structure which could be affected in the emergence of dengue fever cases in Pakistani climate. Principal component is applied to find structure in data for all four periods i.e. 1980 to 2012, 1980 to 1995 and 1996 to 2012.  The first three PCs for the period (1980-2012, 1980-1994, 1995-2012 are almost the same and it represent hot and windy weather. The PC1s of all dengue periods are different to each other. PC2 for all period are same and it is wetness in weather. PC3s are different and it is the combination of wetness and windy weather. PC4s for all period show humid but no rain in weather. For climatic variable only minimum temperature and maximum temperature are significantly correlated with daily dengue cases.  PC1, PC3 and PC4 are highly significantly correlated with daily dengue cases 

  16. Functional and biochemical responses of cultured heart cells to angiotensin II

    Allen, I.; Gaa, S.; Rogers, T.B.

    1986-01-01

    The authors have utilized a cultured neonatal rat heart myocyte system to study the molecular mechanisms involved in the stimulation of heart cells by angiotensin II (AII). The intact cultured cells, and membranes from these cells, have specific, high affinity receptors for 125 I-AII and for an AII antagonist, 125 I-Sar 1 ,Leu 8 -AII. Binding affinity was in the nanomolar range and was inhibited by guanine nucleotides. Functional studies on intact, beating cells revealed a maximal increase in contractile frequency of 50%, observed at 5 nM AII, with half maximal effects noted at around 1 nM. These responses were reversible and specific as the antagonist, Sar 1 , Ala 8 -AII, inhibited AII-induced chronotropic stimulation. AII (100 nM) had no effect on basal adenylate cyclase activity (20 pmoles cAMP/mg prot/min at 2.5mM Mg 2+ ) in cell membranes. Further, in membranes where cyclase activity was stimulated with isoproterenol (290 pmoles cAMP/mg prot/min at 2.5mM Mg 2+ ), addition of AII had no effect. The cyclase-inhibitory muscarinic agonist, carbachol, also failed to reduce isoproterenol-stimulated activity. In preliminary work with the intact cells, AII again did not alter basal cAMP levels (3-10 pmoles cAMP/mg prot). However, the hormone increased isoproterenol-stimulated cAMP levels by almost 50%. These cells are an excellent system for correlating AII receptor binding with functional and biochemical responses

  17. Program management: The keys to a successful ERWM contract

    Lenyk, R.G.; Cusack, J.G.

    1995-01-01

    Program management for a large Environmental Restoration and Waste Management (ERWM) task order contract is both a skill and an art. Unlike project management, program management deals with global and political issues, with both client and home organizations, as well as with day-to-day operations. Program management requires up-front planning and nurturing, for no contract matures successfully by itself. This paper identifies the many opportunities presented in the planning and initial implementation of the contract. Potential traps are identified so that they can be recognized and avoided or mitigated. Teaming and subcontracting are also addressed. The authors rely on years of program management experience to explore such questions as the following: Can you have an integrated team? What needs to be done before you sign Your contract? Do you know who your client(s) is(are)? Have you incorporated the relevant, especially any new, procurement strategies? The US Department of Energy-Oak Ridge Operations (DOE-ORO) ERWM Remedial Design Contract with Foster Wheeler Environmental Corporation is used as a model for exploring these topics. This ERWM Program-which focuses on the Oak Ridge National Laboratory, the Y-12 Weapons Plant, and the K-25 Site in Oak Ridge, Tennessee; the Paducah Gaseous Diffusion Plant in Paducah, Kentucky; and the Portsmouth Gaseous Diffusion Plant in Portsmouth, Ohio-is in its fifth year with over 225 task orders. The program has been highly successful and has obtained from DOE outstanding marks for achieving quality, responsiveness, timeliness, and subcontracting goals

  18. Twitter Analytics: Are the U.S. Coastal Regions Prepared for Climate Change in 2017?

    Singleton, S. L.; Kumar, S.

    2017-12-01

    According to the U.S. National Climate Assessment, the Southeast Coast and Gulf Coast of the United States are particularly susceptible to sea level rise, heat waves, hurricanes and less accessibility to clean water due to climate change. This is because of the extreme variation of topography in these two regions. Preparation for climate change consequences can only occur with conversation, which is a method of bringing awareness to the issue. Over the past decade, social media has taken over the spectrum of information exchange in the United States. Social Network Analysis (SNA) is a field that is emerging with the growth in popularity of social media. SNA is the practice of analyzing trends in volume and opinion of a population of social media users. Twitter, one popular social media platform, is one of the largest microblogging sites in the world, and it provides an abundance of data related to the trending topics such as climate change. Twitter analytics is a type of SNA performed on data from the tweets of Twitter users. In this work, Twitter analytics is performed on the data generated from the Twitter users in the United States, who were talking about climate change, global warming and/or CO2, over the course of one year (July 2016 - June 2017). Specifically, a regional comparative analysis on the coastal U.S. regions was conducted to recognize which region(s) is/are falling behind on the conversation about climate change. Sentiment analysis was also performed to understand the trends in opinion about climate change that vary over time. Experimental results determined that the southeast coast of the United States is deficient in their discussion about climate change compared to the other coastal regions. Igniting the conversation about this issue in these regions will mitigate the disasters due to climate change by increasing awareness in the people of these regions so they can properly prepare.

  19. Oxygen sensitivity of potassium- and angiotensin II-stimulated aldosterone release by bovine adrenal cells.

    Brickner, R C; Raff, H

    1991-04-01

    Angiotensin II (AII) and extracellular K+, acting through different intracellular mechanisms, stimulate aldosterone release in a synergistic fashion. We have previously shown that decreases in oxygen (O2) within the physiological range inhibit AII, cyclic AMP (cAMP) and ACTH-stimulated aldosterone release. The present experiment evaluated the effect of various concentrations of O2 on K+-stimulated aldosterone release in the presence and absence of AII. Dispersed bovine adrenal glomerulosa cells were incubated with different concentrations of K+ (0.9-5.4 mmol/l) without and with AII (10 nmol/l) under different concentrations of O2 (0, 5 or 50%); 21% O2 (pO2 = 19.9 +/- 0.5 kPa,n = 9) was used as reference control for comparison. In all cases, increases in K+ stimulated aldosterone release, an effect augmented by AII. Under 0% O2 (pO2 = 8.1 +/- 0.3 kPa, n = 3) and 5% O2 (pO2 = 12.8 +/- 0.5 kPa, n = 3), aldosterone release stimulated by K+ or K+/AII was significantly inhibited compared with that under 21% O2. Conversely, under 50% O2 (pO2 = 36.3 +/- 2.5 kPa, n = 3), aldosterone release stimulated by K+ or K+/AII was significantly augmented. Cortisol secretion was not significantly affected by 5% or 50% O2 but was significantly decreased under 0% O2. The effect of O2 on K+/AII stimulation of aldosterone release, as well as previous experiments with cAMP, progesterone and ACTH, suggest a final common post-receptor oxygen-sensitive component of the aldosterone synthetic pathway. It is suggested that one or more enzymes in the aldosterone synthetic pathway is/are exquisitely sensitive to small changes in O2 within the physiological range.

  20. The uptake of Continuing Professional Development (CPD) by Ghanaian radiographers

    Gawugah, James N.K.; Jadva-Patel, Hansa; Jackson, Marcus T.

    2011-01-01

    Continuing professional development (CPD) currently gains a priority within healthcare professions all over the globe. It is playing important roles in achieving improved quality care delivery. Healthcare practitioners are expected to continuously undertake CPD to maintain, enhance and improve quality of service delivery to meet the consumers' expectations. CPD offers practitioners the opportunity to retain and enhance the basic knowledge and skills through their working life; thus enhancing competency within one's professional range of practice. In Ghana, awareness of CPD participation has not been created among healthcare practitioners to enable them engage in effective CPD activities in order to improve their knowledge and skills. Purpose: To examine the level of radiographers' participation in CPD activities in Ghana. Method: A 21-item questionnaire was constructed to collect data from 80 participants drawn from among radiographers currently practising in the radiology/X-ray departments of the ten regional hospitals in Ghana. The questionnaire comprised of 3 sections: demographics, CPD and education specific sections. Out of 80 questionnaires administered, 42 were completed and returned representing 52.5%. Out of the percentage, 74% were males and 26% females. The findings highlight that majority (44%) of the participants are currently within the age group of 31-40 years, while 2% is/are 60 or more years. The article also reveals that the radiographers have access to few peer review journals which serve as sources of information on contemporary issues in radiography and CPD learning activities. Again, a generally poor level of CPD awareness among the Ghanaian radiographers has been established. Lack of effective recording of learning and CPD activities have also been revealed. Conclusion: The article concludes by recommending CPD policy guidelines; a regulatory body to register all healthcare professionals under one body to ensure effective CPD participation by

  1. Monitoring the Microgravity Environment Quality On-board the International Space Station Using Soft Computing Techniques. Part 2; Preliminary System Performance Results

    Jules, Kenol; Lin, Paul P.; Weiss, Daniel S.

    2002-01-01

    This paper presents the preliminary performance results of the artificial intelligence monitoring system in full operational mode using near real time acceleration data downlinked from the International Space Station. Preliminary microgravity environment characterization analysis result for the International Space Station (Increment-2), using the monitoring system is presented. Also, comparison between the system predicted performance based on ground test data for the US laboratory "Destiny" module and actual on-orbit performance, using measured acceleration data from the U.S. laboratory module of the International Space Station is presented. Finally, preliminary on-orbit disturbance magnitude levels are presented for the Experiment of Physics of Colloids in Space, which are compared with on ground test data. The ground test data for the Experiment of Physics of Colloids in Space were acquired from the Microgravity Emission Laboratory, located at the NASA Glenn Research Center, Cleveland, Ohio. The artificial intelligence was developed by the NASA Glenn Principal Investigator Microgravity Services Project to help the principal investigator teams identify the primary vibratory disturbance sources that are active, at any moment of time, on-board the International Space Station, which might impact the microgravity environment their experiments are exposed to. From the Principal Investigator Microgravity Services' web site, the principal investigator teams can monitor via a dynamic graphical display, implemented in Java, in near real time, which event(s) is/are on, such as crew activities, pumps, fans, centrifuges, compressor, crew exercise, structural modes, etc., and decide whether or not to run their experiments, whenever that is an option, based on the acceleration magnitude and frequency sensitivity associated with that experiment. This monitoring system detects primarily the vibratory disturbance sources. The system has built-in capability to detect both known

  2. Adapting regional watershed management to climate change in Bavaria and Québec

    Ludwig, Ralf; Muerth, Markus; Schmid, Josef; Jobst, Andreas; Caya, Daniel; Gauvin St-Denis, Blaise; Chaumont, Diane; Velazquez, Juan-Alberto; Turcotte, Richard; Ricard, Simon

    2013-04-01

    The international research project QBic3 (Quebec-Bavarian Collaboration on Climate Change) aims at investigating the potential impacts of climate change on the hydrology of regional scale catchments in Southern Quebec (Canada) and Bavaria (Germany). For this purpose, a hydro-meteorological modeling chain has been established, applying climatic forcing from both dynamical and statistical climate model data to an ensemble of hydrological models of varying complexity. The selection of input data, process descriptions and scenarios allows for the inter-comparison of the uncertainty ranges on selected runoff indicators; a methodology to display the relative importance of each source of uncertainty is developed and results for past runoff (1971-2000) and potential future changes (2041-2070) are obtained. Finally, the impact of hydrological changes on the operational management of dams, reservoirs and transfer systems is investigated and shown for the Bavarian case studies, namely the potential change in i) hydro-power production for the Upper Isar watershed and ii) low flow augmentation and water transfer rates at the Donau-Main transfer system in Central Franconia. Two overall findings will be presented and discussed in detail: a) the climate change response of selected hydrological indicators, especially those related to low flows, is strongly affected by the choice of the hydrological model. It can be shown that an assessment of the changes in the hydrological cycle is best represented by a complex physically based hydrological model, computationally less demanding models (usually simple, lumped and conceptual) can give a significant level of trust for selected indicators. b) the major differences in the projected climate forcing stemming from the ensemble of dynamic climate models (GCM/RCM) versus the statistical-stochastical WETTREG2010 approach. While the dynamic ensemble reveals a moderate modification of the hydrological processes in the investigated catchments

  3. IoSiS: a radar system for imaging of satellites in space

    Jirousek, M.; Anger, S.; Dill, S.; Schreiber, E.; Peichl, M.

    2017-05-01

    Space debris nowadays is one of the main threats for satellite systems especially in low earth orbit (LEO). More than 700,000 debris objects with potential to destroy or damage a satellite are estimated. The effects of an impact often are not identifiable directly from ground. High-resolution radar images are helpful in analyzing a possible damage. Therefor DLR is currently developing a radar system called IoSiS (Imaging of Satellites in Space), being based on an existing steering antenna structure and our multi-purpose high-performance radar system GigaRad for experimental investigations. GigaRad is a multi-channel system operating at X band and using a bandwidth of up to 4.4 GHz in the IoSiS configuration, providing fully separated transmit (TX) and receive (RX) channels, and separated antennas. For the observation of small satellites or space debris a highpower traveling-wave-tube amplifier (TWTA) is mounted close to the TX antenna feed. For the experimental phase IoSiS uses a 9 m TX and a 1 m RX antenna mounted on a common steerable positioner. High-resolution radar images are obtained by using Inverse Synthetic Aperture Radar (ISAR) techniques. The guided tracking of known objects during overpass allows here wide azimuth observation angles. Thus high azimuth resolution comparable to the range resolution can be achieved. This paper outlines technical main characteristics of the IoSiS radar system including the basic setup of the antenna, the radar instrument with the RF error correction, and the measurement strategy. Also a short description about a simulation tool for the whole instrument and expected images is shown.

  4. Flow measurements in biological systems using Xe-127 and Xe-133

    Tripathi, R.R.

    1981-01-01

    Xe-133 and Xe-127 are widely used for quantitative evaluation of ventilation in human subjects. Owing to differences in scattering in the biological system as well as differences in the detector response to photons of selected energies, clinical Xe-133 images are much more distorted than the corresponding Xe-127 images. This thesis concerns itself with the evaluation of Xe-133 and Xe-127 as potential tracers for pulmonary function studies. Through the simulation of clinical images it is shown that such smaller abnormalities are able to be detected with Xe-127 than with Xe-133. It is also found that even for poorly ventilated regions, the measured lesion size in the simulated image is comparable to the known lesion size when studied with Xe-127. With Xe-133, however, the measured size of the lesion is smaller than its known size. By fitting the washout portion of the clinical data to a linear sum of two exponentials, a weighted average clearance constant for the tracer - which relates to the reciprocal of the mean flow through the system - can be calculated and used as an index for comparison of the two Xenon isotopes. When an appropriate model is used for data interpretation, more accurate clinical information can be derived from the Xe-127 data. Unlike Xe-133, ventilation study with Xe-127 can be performed immediately after the perfusion study with Tc-99m. Lower radiation dose and longer shelf-life of Xe-127 are added advantages over Xe-133. Various compartmental and non-compartmental models are examined and appropriate technique(s) for clinical data interpretation is(are) recommended

  5. Clinical utility of 18-FDG-PET with a modified SPECT-camera using molecular coincidence detection in oncology

    Gabriel, M. F.

    1998-09-01

    Malignant diseases are belonging to one of the most frequent reasons for mortality and morbidity of people in industrialized countries. In order to avoid inadequate therapy such as unnecessary operations etc. accurate diagnostic techniques are needed to assess malignancy of proven lesions, for staging of cancer or to assess success of therapy. Many studies have reported the value of PET in such cases. Because of limited financial resources we started PET with a Dual-head-SPECT-camera modified with a MCD-module in February 1997 in order to obtain quick access to clinical 18-FDG studies. The aim of this work was to compare the results of our system with reports of the so called 'state of the art'-PET and with other diagnostic techniques used in clinical oncology. So far 124 studies were performed with the MCD-mode using a standardized investigation protocol between February 1997 and May 1998. The applied dose of 18-FDG for oncological studies was about 185 MBq. The tracer was supplied from the radio-pharmaceutical unit of the Department of Nuclear Medicine, Klinikum Rechts der Isar, Technische Universitaet Muenchen. The obtained results were carefully compared with CT, MRI and conventional radiology. In addition, the final diagnosis (based on histology, surgical reports, autopsy and follow up) was also considered. Oncological studies were done either to assess malignancy in certain lesions (n = 25), for staging cancer (n = 77), or to assess success of therapy (n = 22). Sensitivity and specificity for all oncological cases were 99 % and 89 % respectively. One false negative scan was a pretreated CNS-lymphoma, where false positive studies were due to inflammation. (author)

  6. Effects of short-term piano training on measures of finger tapping, somatosensory perception and motor-related brain activity in patients with cerebral palsy

    Alves-Pinto A

    2017-10-01

    Full Text Available Ana Alves-Pinto,1 Stefan Ehrlich,2 Gordon Cheng,2 Varvara Turova,1 Tobias Blumenstein,1 Renée Lampe1 1Research Unit of the Buhl-Strohmaier Foundation for Paediatric Neuroorthopaedics and Cerebral Palsy, Department of Orthopaedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; 2Chair for Cognitive Systems, Department of Electrical and Computer Engineering, Technical University of Munich, Munich, Germany Abstract: Playing a musical instrument demands the integration of sensory and perceptual information with motor processes in order to produce a harmonic musical piece. The diversity of brain mechanisms involved and the joyful character of playing an instrument make musical instrument training a potential vehicle for neurorehabilitation of motor skills in patients with cerebral palsy (CP. This clinical condition is characterized by motor impairments that can affect, among others, manual function, and limit severely the execution of basic daily activities. In this study, adolescents and adult patients with CP, as well as a group of typically developing children learned to play piano for 4 consecutive weeks, having completed a total of 8 hours of training. For ten of the participants, learning was supported by a special technical system aimed at helping people with sensorimotor deficits to better discriminate fingers and orient themselves along the piano keyboard. Potential effects of piano training were assessed with tests of finger tapping at the piano and tests of perception of vibratory stimulation of fingers, and by measuring neuronal correlates of motor learning in the absence of and after piano training. Results were highly variable especially among participants with CP. Nevertheless, a significant effect of training on the ability to perceive the localization of vibrations over fingers was found. No effects of training on the performance of simple finger tapping sequences at the piano or on motor

  7. Worsening calcification propensity precedes all-cause and cardiovascular mortality in haemodialyzed patients.

    Lorenz, Georg; Steubl, Dominik; Kemmner, Stephan; Pasch, Andreas; Koch-Sembdner, Wilhelm; Pham, Dang; Haller, Bernhard; Bachmann, Quirin; Mayer, Christopher C; Wassertheurer, Siegfried; Angermann, Susanne; Lech, Maciej; Moog, Philipp; Bauer, Axel; Heemann, Uwe; Schmaderer, Christoph

    2017-10-17

    A novel in-vitro test (T 50 -test) assesses ex-vivo serum calcification propensity which predicts mortality in HD patients. The association of longitudinal changes of T 50 with all-cause and cardiovascular mortality has not been investigated. We assessed T 50 in paired sera collected at baseline and at 24 months in 188 prevalent European HD patients from the ISAR cohort, most of whom were Caucasians. Patients were followed for another 19 [interquartile range: 11-37] months. Serum T 50 exhibited a significant decline between baseline and 24 months (246 ± 64 to 190 ± 68 minutes; p < 0.001). With serum Δ-phosphate showing the strongest independent association with declining T 50 (r = -0.39; p < 0.001) in multivariable linear regression. The rate of decline of T 50 over 24 months was a significant predictor of all-cause (HR = 1.51 per 1SD decline, 95% CI: 1.04 to 2.2; p = 0.03) and cardiovascular mortality (HR = 2.15; 95% CI: 1.15 to 3.97; p = 0.02) in Kaplan Meier and multivariable Cox-regression analysis, while cross-sectional T 50 at inclusion and 24 months were not. Worsening serum calcification propensity was an independent predictor of mortality in this small cohort of prevalent HD patients. Prospective larger scaled studies are needed to assess the value of calcification propensity as a longitudinal parameter for risk stratification and monitoring of therapeutic interventions.

  8. Protection of quality and innovation in radiation oncology: The prospective multicenter trial the German Society of Radiation Oncology (DEGRO-QUIRO study). Evaluation of time, attendance of medical staff, and resources during radiotherapy with IMRT

    Vorwerk, H.; Schiller, R.; Zink, K.; Engenhart-Cabillic, R.; Budach, V.; Boehmer, D.; Kampfer, S.; Popp, W.; Sack, H.

    2014-01-01

    A number of national and international societies published recommendations regarding the required equipment and manpower assumed to be necessary to treat a number of patients with radiotherapy. None of these recommendations were based on actual time measurements needed for specific radiotherapy procedures. The German Society of Radiation Oncology (DEGRO) was interested in substantiating these recommendations by prospective evaluations of all important core procedures of radiotherapy in the most frequent cancers treated by radiotherapy. The results of the examinations of radiotherapy with intensity-modulated radiation therapy (IMRT) in patients with different tumor entities are presented in this manuscript. Four radiation therapy centers [University Hospital of Marburg, University Hospital of Giessen, University Hospital of Berlin (Charite), Klinikum rechts der Isar der Technischen Universitaet Muenchen] participated in this prospective study. The workload of the different occupational groups and room occupancies for the core procedures of radiotherapy were prospectively documented during a 2-month period per center and subsequently statistically analyzed. The time needed per patient varied considerably between individual patients and between centers for all the evaluated procedures. The technical preparation (contouring of target volume and organs at risk, treatment planning, and approval of treatment plan) was the most time-consuming process taking 3 h 54 min on average. The time taken by the medical physicists for this procedure amounted to about 57 %. The training part of the preparation time was 87 % of the measured time for the senior physician and resident. The total workload for all involved personnel comprised 74.9 min of manpower for the first treatment, 39.7 min for a routine treatment with image guidance, and 22.8 min without image guidance. The mean room occupancy varied between 10.6 min (routine treatment without image guidance) and 23.7 min (first

  9. Differences between state entropy and bispectral index during analysis of identical electroencephalogram signals: a comparison with two randomised anaesthetic techniques.

    Pilge, Stefanie; Kreuzer, Matthias; Karatchiviev, Veliko; Kochs, Eberhard F; Malcharek, Michael; Schneider, Gerhard

    2015-05-01

    It is claimed that bispectral index (BIS) and state entropy reflect an identical clinical spectrum, the hypnotic component of anaesthesia. So far, it is not known to what extent different devices display similar index values while processing identical electroencephalogram (EEG) signals. To compare BIS and state entropy during analysis of identical EEG data. Inspection of raw EEG input to detect potential causes of erroneous index calculation. Offline re-analysis of EEG data from a randomised, single-centre controlled trial using the Entropy Module and an Aspect A-2000 monitor. Klinikum rechts der Isar, Technische Universität München, Munich. Forty adult patients undergoing elective surgery under general anaesthesia. Blocked randomisation of 20 patients per anaesthetic group (sevoflurane/remifentanil or propofol/remifentanil). Isolated forearm technique for differentiation between consciousness and unconsciousness. Prediction probability (PK) of state entropy to discriminate consciousness from unconsciousness. Correlation and agreement between state entropy and BIS from deep to light hypnosis. Analysis of raw EEG compared with index values that are in conflict with clinical examination, with frequency measures (frequency bands/Spectral Edge Frequency 95) and visual inspection for physiological EEG patterns (e.g. beta or delta arousal), pathophysiological features such as high-frequency signals (electromyogram/high-frequency EEG or eye fluttering/saccades), different types of electro-oculogram or epileptiform EEG and technical artefacts. PK of state entropy was 0.80 and of BIS 0.84; correlation coefficient of state entropy with BIS 0.78. Nine percent BIS and 14% state entropy values disagreed with clinical examination. Highest incidence of disagreement occurred after state transitions, in particular for state entropy after loss of consciousness during sevoflurane anaesthesia. EEG sequences which led to false 'conscious' index values often showed high

  10. Experiments on a Toroidal Screw Pinch with Various Field Programming

    Zwicker, H.; Wilhelm, R.; Krause, H. [Max-Planck-Institut Fuer Plasmaphysik, EURATOM-Association, Garching, Munich, Federal Republic of Germany (Germany)

    1971-10-15

    In the toroidal screw pinch ISAR-IV (large diameter 60 cm, aspect ratio 5, maximum storage, energy 140 kj) attempts were made to get an improved stability of the plasma by different kinds of field programming. The best results were obtained with positive trapped B{sub z}-fields and simultaneous switching of main B{sub z}-field and I{sub z}-current. In this case the dense plasma column (n{sub e} Almost-Equal-To 2-3 x 10{sup 16} , kT Almost-Equal-To 50-100 eV, {beta} Almost-Equal-To 15-20%) is surrounded by a force-free plasma ({beta} = 1%) with weak shear and it behaves stably for, at least, 25 {mu}s. The resulting containment time nr of near 10{sup 12} s cm{sup -3} remains a factor of 2-3 below the upper limit given by the classical diffusion. The following loss of the equilibrium position near the coil axis ({Delta} Almost-Equal-To 1-2 cm) is connected to a strong damping of the axial plasma current which starts near the end of the containment. It may be assumed that the increase of the effective plasma resistance mainly results from a contact of the force-free regions with the tube wall. Attempts were made to improve the containment by suitable programming of a plasma z-current. The results are presented. Experiments with one quartz limiter inside the torus improved the equilibrium but introduced instabilities at the new surface of the dilute plasma. To obtain more information about the outer region, the dilute plasma was produced without a dense core and separated from the tube walls by weak adiabatic compression. Under these Tokamak-like conditions the q-value was varied. In the region of q Almost-Equal-To 1 there appeared instabilities which seem to haver higher m-modes and rather short wavelengths. In a different kind of field programming the field distribution of the ''diffuse pinch'' was realized within an accuracy of 5-10% (kT Almost-Equal-To 100 eV, {beta} Almost-Equal-To 30%). In contrast to the predictions of MHD-theory, stability was observed only for

  11. Accountability studies of air pollution and health effects: lessons learned and recommendations for future natural experiment opportunities

    Rich, David Q.

    2017-01-01

    To address limitations of observational epidemiology studies of air pollution and health effects, including residual confounding by temporal and spatial factors, several studies have taken advantage of ‘natural experiments’, where an environmental policy or air quality intervention has resulted in reductions in ambient air pollution concentrations. Researchers have examined whether the population impacted by these air quality improvements, also experienced improvements in various health indices (e.g. reduced morbidity/mortality). In this paper, I review key accountability studies done previously and new studies done over the past several years in Beijing, Atlanta, London, Ireland, and other locations, describing study design and analysis strengths and limitations of each. As new ‘natural experiment’ opportunities arise, several lessons learned from these studies should be applied when planning a new accountability study. Comparison of health outcomes during the intervention to both before and after the intervention in the population of interest, as well as use of a control population to assess whether any temporal changes in the population of interest were also seen in populations not impacted by air quality improvements, should aid in minimizing residual confounding by these long term time trends. Use of either detailed health records for a population, or prospectively collected data on relevant mechanistic biomarkers coupled with such morbidity/mortality data may provide a more thorough assessment of if the intervention beneficially impacted the health of the community, and if so by what mechanism(s). Further, prospective measurement of a large suite of air pollutants may allow a more thorough understanding of what pollutant source(s) is/are responsible for any health benefit observed. The importance of using multiple statistical analysis methods in each paper and the difference in how the timing of the air pollution/outcome association may impact which

  12. Frontotemporal lobar degeneration: current perspectives

    Riedl L

    2014-02-01

    Full Text Available Lina Riedl,1 Ian R Mackenzie,2 Hans Förstl,1 Alexander Kurz,1 Janine Diehl-Schmid1 1Center for Cognitive Disorders, Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Munich, Germany; 2Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada Abstract: The term frontotemporal lobar degeneration (FTLD refers to a group of progressive brain diseases, which preferentially involve the frontal and temporal lobes. Depending on the primary site of atrophy, the clinical manifestation is dominated by behavior alterations or impairment of language. The onset of symptoms usually occurs before the age of 60 years, and the mean survival from diagnosis varies between 3 and 10 years. The prevalence is estimated at 15 per 100,000 in the population aged between 45 and 65 years, which is similar to the prevalence of Alzheimer's disease in this age group. There are two major clinical subtypes, behavioral-variant frontotemporal dementia and primary progressive aphasia. The neuropathology underlying the clinical syndromes is also heterogeneous. A common feature is the accumulation of certain neuronal proteins. Of these, the microtubule-associated protein tau (MAPT, the transactive response DNA-binding protein, and the fused in sarcoma protein are most important. Approximately 10% to 30% of FTLD shows an autosomal dominant pattern of inheritance, with mutations in the genes for MAPT, progranulin (GRN, and in the chromosome 9 open reading frame 72 (C9orf72 accounting for more than 80% of familial cases. Although significant advances have been made in recent years regarding diagnostic criteria, clinical assessment instruments, neuropsychological tests, cerebrospinal fluid biomarkers, and brain imaging techniques, the clinical diagnosis remains a challenge. To date, there is no specific pharmacological treatment for FTLD. Some evidence has been provided for serotonin reuptake

  13. Advocating neuroimaging studies of transmitter release in human physical exercise challenges studies

    Henning Boecker

    2010-09-01

    Full Text Available Henning Boecker1, Ahmed Othman1, Sarah Mueckter1, Lukas Scheef1, Max Pensel1, Marcel Daamen1, Jakob Jankowski1, HH Schild2, TR Tölle3, M Schreckenberger41FE Klinische Funktionelle Neurobildgebung, Radiologische Universitätsklinik, Friedrich-Wilhelms–Universität Bonn, Germany; 2Radiologische Universitätsklinik, Friedrich-Wilhelms-Universität Bonn, Germany; 3TUM Neurologische Klinik und Poliklinik im Neuro-Kopf-Zentrum, Klinikum rechts der Isar der Technischen Universität München, München, Germany; 4Klinik und Poliklinik für Nuklearmedizin am Mainzer Universitätsklinikum, Johannes Gutenberg-Universität, Mainz, GermanyAbstract: This perspective attempts to outline the emerging role of positron emission tomography (PET ligand activation studies in human exercise research. By focusing on the endorphinergic system and its acclaimed role for exercise-induced antinociception and mood enhancement, we like to emphasize the unique potential of ligand PET applied to human athletes for uncovering the neurochemistry of exercise-induced psychophysiological phenomena. Compared with conventional approaches, in particular quantification of plasma beta-endorphin levels under exercise challenges, which are reviewed in this article, studying opioidergic effects directly in the central nervous system (CNS with PET and relating opioidergic binding changes to neuropsychological assessments, provides a more refined and promising experimental strategy. Although a vast literature dating back to the 1980s of the last century has been able to reproducibly demonstrate peripheral increases of beta-endorphin levels after various exercise challenges, so far, these studies have failed to establish robust links between peripheral beta-endorphin levels and centrally mediated behavioral effects, ie, modulation of mood and/or pain perception. As the quantitative relation between endorphins in the peripheral blood and the CNS remains unknown, the question arises, to what

  14. Increased Concentrations of Short-Lived Decay-Series Radionuclides in Groundwaters Underneath the Nopal I Uranium Deposit at Pena Blanca, Mexico

    Luo, S.; Ku, T.; Todd, V.; Murrell, M. T.; Dinsmoor, J. C.

    2007-05-01

    The Nopal I uranium ore deposit at Pena Blanca, Mexico, located at > 200 meters above the groundwater table, provides an ideal natural analog for quantifying the effectiveness of geological barrier for isolation of radioactive waste nuclides from reaching the human environments through ground water transport. To fulfill such natural analog studies, three wells (PB1, PB2, and PB3 respectively) were drilled at the site from the land surface down to the saturated groundwater zone and ground waters were collected from each of these wells through large- volume sampling/in-situ Mn-filter filtration for analyses of short-lived uranium/thorium-series radionuclides. Our measurements from PB1 show that the groundwater standing in the hole has much lower 222Rn activity than the freshly pumped groundwater. From this change in 222Rn activity, we estimate the residence time of groundwater in PB1 to be about 20 days. Our measurements also show that the activities of short-lived radioisotopes of Th (234Th), Ra (228Ra, 224Ra, 223Ra), Rn (222Rn), Pb (210Pb), and Po (210Po) in PB1, PB2, and PB3 are all significantly higher than those from the other wells near the Nopal I site. These high activities provide evidence for the enrichment of long-lived U and Ra isotopes in the groundwater as well as in the associated adsorbed phases on the fractured aquifer rocks underneath the ore deposit. Such enrichment suggests a rapid dissolution of U and Ra isotopes from the uranium ore deposit in the vadose zone and the subsequent migration to the groundwater underneath. A reactive transport model can be established to characterize the in-situ transport of radionuclides at the site. The observed change of 222Rn activity at PB1 also suggests that the measured high radioactivityies in ground waters from the site isare not an artifact of drilling operations. However, further studies are needed to assess if or to what extent the radionuclide migration is affected by the previous mining activities at

  15. The Federal Administrative Court confirms unlawfulness of nuclear power moratorium. Political primacy is only valid in the bounds of justice; Bundesverwaltungsgericht bestaetigt Rechtswidrigkeit des Kernkraftmoratoriums. Primat der Politik gilt nur in den Schranken des Rechts

    Leidinger, Tobias [Gleiss-Lutz Rechtsanwaelte, Duesseldorf (Germany)

    2014-03-15

    With its decision on December 20{sup th}, the Federal Administrative Court (BVwerfG) came to the legally valid conclusion that after the Fukushima nuclear power plant accident, the supervision court order related to the law on nuclear installation by the Hessian Ministry for the Environment, in order to stop operating nuclear power plants Biblis A and B for 3 months or rather not to put in operation again, was unlawful (BVwerfG 7 B 18.13 und 7 B 19.13). Beforehand, the Hessian Administrative Court (Hess. VGH) had already pronounced its judgement on February 27{sup th} 2013. The supervising orders were part of the so-called nuclear power moratorium. They were issued after the resolution of the federal government, at demand of the Federal Ministry for the Environment, Nature Conservation and Nuclear Safety (BMU) towards their nearby countries, and were identically executed by the supervisory authority of the other site-countries. Besides Biblis in Hesse, nuclear power plants in Neckarwestheim I and Philippsburg 1, Baden-Wurttemberg, Isar 1 in Bavaria, Unterweser in Lower Saxony, as well as Brunsbuettel in Schleswig-Holstein, were affected. However only RWE took legal action and was now affirmed - after the Hessian VGH verdict- by the highest German administrative court: The nuclear power moratorium - the first step to withdrawal of nuclear power in Germany - was unlawful. The decision taken by the BVerwG - as well as the one by the Hessian VGH - indicates a juridical clear and precise argumentation. The partially polemic and unobjective critic, which the VHG-verdict experienced, did not disguise, just as little as the political conflict concerning the withdrawal from nuclear energy, the view of federal judges, regarding the decision-relevant questions nor did they influence their reply. The political primacy finds its limits in the bounds of justice. Existing rights do not become thus a paper waste because there is a fundamental decision. This takes effectiveness for

  16. Spotlight on rituximab in the treatment of antineutrophil cytoplasmic antibody-associated vasculitis: current perspectives

    Moog P

    2015-11-01

    Full Text Available Philipp Moog, Klaus Thuermel Abteilung für Nephrologie, Klinikum rechts der Isar, Technische Universität München, Munich, Germany Abstract: A 54-year-old patient presented to his general practitioner because of strong muscle pain in both thighs. Inflammatory parameters (CRP 16.3 mg/dL and white blood cells (15 g/L were elevated. The patient reported a weight loss of 10 kg in 4 weeks. There was no fever or any other specific symptoms. Urine dipstick examination and computed tomography of the chest were unremarkable. Because of increasing symptoms, the patient was referred to our department. Magnetic resonance tomography showed diffuse inflammatory changes of the muscles of both thighs. Neurological examination and electrophysiology revealed axonal sensorimotor neuropathy and ground-glass opacities of both lungs had occurred. Serum creatinine increased to 229 µmol/L within a few days, with proteinuria of 3.3 g/g creatinine. Kidney biopsy showed diffuse pauci-immune proliferative glomerulonephritis. Proteinase 3-specific antineutrophil cytoplasmic antibodies were markedly increased. Birmingham Vasculitis Activity Score was 35. Within 2 days, serum creatinine further increased to 495 µmol/L. Plasma exchange, high-dose glucocorticosteroids, and hemodialysis were started. The patient received cyclophosphamide 1 g twice and rituximab 375 mg/m2 four times according to the RITUXVAS protocol. Despite ongoing therapy, hemodialysis could not be withdrawn and had to be continued over 3 weeks until diuresis normalized. Glucocorticosteroids were tapered to 20 mg after 2 months, and serum creatinine was 133 µmol/L. However, nephritic urinary sediment reappeared. Another dose of 1 g cyclophosphamide was given, and glucocorticosteroids were raised for another 4 weeks. After 6 months, the daily prednisolone dose was able to be tapered to 5 mg. Serum creatinine was 124 µmol/L, proteinuria further decreased to 382 mg/g creatinine, and the Birmingham

  17. Advances in Small Remotely Piloted Aircraft Communications and Remote Sensing in Maritime Environments including the Arctic

    McGillivary, P. A.; Borges de Sousa, J.; Wackowski, S.; Walker, G.

    2011-12-01

    Small remotely piloted aircraft have recently been used for maritime remote sensing, including launch and retrieval operations from land, ships and sea ice. Such aircraft can also function to collect and communicate data from other ocean observing system platforms including moorings, tagged animals, drifters, autonomous surface vessels (ASVs), and autonomous underwater vessels (AUVs). The use of small remotely piloted aircraft (or UASs, unmanned aerial systems) with a combination of these capabilities will be required to monitor the vast areas of the open ocean, as well as in harsh high-latitude ecosystems. Indeed, these aircraft are a key component of planned high latitude maritime domain awareness environmental data collection capabilities, including use of visible, IR and hyperspectral sensors, as well as lidar, meteorological sensors, and interferometric synthetic aperture radars (ISARs). We here first describe at-sea demonstrations of improved reliability and bandwidth of communications from ocean sensors on autonomous underwater vehicles to autonomous surface vessels, and then via remotely piloted aircraft to shore, ships and manned aircraft using Delay and Disruption Tolerant (DTN) communication protocols. DTN enables data exchange in communications-challenged environments, such as remote regions of the ocean including high latitudes where low satellite angles and auroral disturbances can be problematic. DTN provides a network architecture and application interface structured around optionally-reliable asynchronous message forwarding, with limited expectations of end-to-end connectivity and node resources. This communications method enables aircraft and surface vessels to function as data mules to move data between physically disparate nodes. We provide examples of the uses of this communication protocol for environmental data collection and data distribution with a variety of different remotely piloted aircraft in a coastal ocean environment. Next, we

  18. Indole-3-butyric acid promotes adventitious rooting in Arabidopsis thaliana thin cell layers by conversion into indole-3-acetic acid and stimulation of anthranilate synthase activity.

    Fattorini, L; Veloccia, A; Della Rovere, F; D'Angeli, S; Falasca, G; Altamura, M M

    2017-07-11

    Indole-3-acetic acid (IAA), and its precursor indole-3-butyric acid (IBA), control adventitious root (AR) formation in planta. Adventitious roots are also crucial for propagation via cuttings. However, IBA role(s) is/are still far to be elucidated. In Arabidopsis thaliana stem cuttings, 10 μM IBA is more AR-inductive than 10 μM IAA, and, in thin cell layers (TCLs), IBA induces ARs when combined with 0.1 μM kinetin (Kin). It is unknown whether arabidopsis TCLs produce ARs under IBA alone (10 μM) or IAA alone (10 μM), and whether they contain endogenous IAA/IBA at culture onset, possibly interfering with the exogenous IBA/IAA input. Moreover, it is unknown whether an IBA-to-IAA conversion is active in TCLs, and positively affects AR formation, possibly through the activity of the nitric oxide (NO) deriving from the conversion process. Revealed undetectable levels of both auxins at culture onset, showing that arabidopsis TCLs were optimal for investigating AR-formation under the total control of exogenous auxins. The AR-response of TCLs from various ecotypes, transgenic lines and knockout mutants was analyzed under different treatments. It was shown that ARs are better induced by IBA than IAA and IBA + Kin. IBA induced IAA-efflux (PIN1) and IAA-influx (AUX1/LAX3) genes, IAA-influx carriers activities, and expression of ANTHRANILATE SYNTHASE -alpha1 (ASA1), a gene involved in IAA-biosynthesis. ASA1 and ANTHRANILATE SYNTHASE -beta1 (ASB1), the other subunit of the same enzyme, positively affected AR-formation in the presence of exogenous IBA, because the AR-response in the TCLs of their mutant wei2wei7 was highly reduced. The AR-response of IBA-treated TCLs from ech2ibr10 mutant, blocked into IBA-to-IAA-conversion, was also strongly reduced. Nitric oxide, an IAA downstream signal and a by-product of IBA-to-IAA conversion, was early detected in IAA- and IBA-treated TCLs, but at higher levels in the latter explants. Altogether, results showed that IBA induced

  19. Accountability studies of air pollution and health effects: lessons learned and recommendations for future natural experiment opportunities.

    Rich, David Q

    2017-03-01

    To address limitations of observational epidemiology studies of air pollution and health effects, including residual confounding by temporal and spatial factors, several studies have taken advantage of 'natural experiments', where an environmental policy or air quality intervention has resulted in reductions in ambient air pollution concentrations. Researchers have examined whether the population impacted by these air quality improvements, also experienced improvements in various health indices (e.g. reduced morbidity/mortality). In this paper, I review key accountability studies done previously and new studies done over the past several years in Beijing, Atlanta, London, Ireland, and other locations, describing study design and analysis strengths and limitations of each. As new 'natural experiment' opportunities arise, several lessons learned from these studies should be applied when planning a new accountability study. Comparison of health outcomes during the intervention to both before and after the intervention in the population of interest, as well as use of a control population to assess whether any temporal changes in the population of interest were also seen in populations not impacted by air quality improvements, should aid in minimizing residual confounding by these long term time trends. Use of either detailed health records for a population, or prospectively collected data on relevant mechanistic biomarkers coupled with such morbidity/mortality data may provide a more thorough assessment of if the intervention beneficially impacted the health of the community, and if so by what mechanism(s). Further, prospective measurement of a large suite of air pollutants may allow a more thorough understanding of what pollutant source(s) is/are responsible for any health benefit observed. The importance of using multiple statistical analysis methods in each paper and the difference in how the timing of the air pollution/outcome association may impact which of these

  20. The Federal Administrative Court confirms unlawfulness of nuclear power moratorium. Political primacy is only valid in the bounds of justice

    Leidinger, Tobias

    2014-01-01

    With its decision on December 20 th , the Federal Administrative Court (BVwerfG) came to the legally valid conclusion that after the Fukushima nuclear power plant accident, the supervision court order related to the law on nuclear installation by the Hessian Ministry for the Environment, in order to stop operating nuclear power plants Biblis A and B for 3 months or rather not to put in operation again, was unlawful (BVwerfG 7 B 18.13 und 7 B 19.13). Beforehand, the Hessian Administrative Court (Hess. VGH) had already pronounced its judgement on February 27 th 2013. The supervising orders were part of the so-called nuclear power moratorium. They were issued after the resolution of the federal government, at demand of the Federal Ministry for the Environment, Nature Conservation and Nuclear Safety (BMU) towards their nearby countries, and were identically executed by the supervisory authority of the other site-countries. Besides Biblis in Hesse, nuclear power plants in Neckarwestheim I and Philippsburg 1, Baden-Wurttemberg, Isar 1 in Bavaria, Unterweser in Lower Saxony, as well as Brunsbuettel in Schleswig-Holstein, were affected. However only RWE took legal action and was now affirmed - after the Hessian VGH verdict- by the highest German administrative court: The nuclear power moratorium - the first step to withdrawal of nuclear power in Germany - was unlawful. The decision taken by the BVerwG - as well as the one by the Hessian VGH - indicates a juridical clear and precise argumentation. The partially polemic and unobjective critic, which the VHG-verdict experienced, did not disguise, just as little as the political conflict concerning the withdrawal from nuclear energy, the view of federal judges, regarding the decision-relevant questions nor did they influence their reply. The political primacy finds its limits in the bounds of justice. Existing rights do not become thus a paper waste because there is a fundamental decision. This takes effectiveness for

  1. Pegaptanib sodium treatment in neovascular age-related macular degeneration: clinical experience in Germany

    Nikolaus Feucht

    2008-06-01

    Full Text Available Nikolaus Feucht, Huebner Matthias, Chris P Lohmann, Mathias MaierAugenklinik rechts der Isar, Technical University Munich, GermanyBackground: The VEGF Inhibition Study In Ocular Neovascularisation (VISION reported the efficacy of intravitreal (ITV vascular endothelial growth factor (VEGF inhibition with pegaptanib sodium (Macugen® for the treatment of neovascular age-related macular degeneration (AMD. This paper reports clinical experience with pegaptanib sodium for the treatment of occult or minimally classic choroidal neovascularization (CNV due to AMD.Material and methods: The study included 50 eyes (in 49 patients with either occult CNV or minimally classic CNV secondary to neovascular AMD who were not eligible for photodynamic therapy (PDT. Study data were analyzed retrospectively. During the 6-month study, patients were administered an average 2.74 injections of 0.3 mg ITV pegaptanib sodium. Angiography and optical coherence tomography (OCT examinations were carried out and intraocular pressure (IOP and visual acuity (VA were measured at baseline, at 3 months and at 6 months. An eye examination was performed and VA was measured the 2 days following treatment and then again at weeks 4–6, and at 3 and 6 months. OCT, VA, and IOP were also assessed at 1 month.Results: ITV pegaptanib sodium was well tolerated and no treatment complications arose. Mean VA was measured as: 0.37 ± 0.24 at baseline; 0.37 ± 0.25 at 1 month; 0.37 ± 0.25 at 3 months and 0.40 ± 0.26 at 6 months. VA was stabilized in approximately 90% of eyes treated with pegaptanib sodium. OCT examination showed a minimal change in central retinal thickness (CRT during the course of the study, from 251.19 µm at baseline to 251.63 µm at 6 months. No elevation in IOP was measured during treatment at 4–6 months in patients receiving pegaptanib sodium.Conclusions: ITV therapy with pegaptanib sodium for occult and minimally classic CNV secondary to neovascular AMD offered good

  2. Which Obstacles Prevent Us from Recruiting into Clinical Trials: A Survey about the Environment for Clinical Studies at a German University Hospital in a Comprehensive Cancer Center

    Christoph Straube

    2017-08-01

    Full Text Available BackgroundProspective clinical studies are the most important tool in modern medicine. The standard in good clinical practice in clinical trials has constantly improved leading to more sophisticated protocols. Moreover, translational questions are increasingly addressed in clinical trials. Such trials must follow elaborate rules and regulations. This is accompanied by a significant increase in documentation issues which require substantial manpower. Furthermore, university-based clinical centers are interested in increasing the amount of patients treated within clinical trials, and this number has evolved to be a key quality criterion. The present study was initiated to elucidate the obstacles that limit clinical scientists in screening and recruiting for clinical trials.MethodsA specific questionnaire with 28 questions was developed focusing on all aspects of clinical trial design as well as trial management. This included questions on organizational issues, medical topics as well as potential patients’ preferences and physician’s goals. The questionnaire was established to collect data anonymously on a web-based platform. The survey was conducted within the Klinikum rechts der Isar, Faculty of Medicine, Technical University of Munich; physicians of all levels (Department Chairs, attending physicians, residents, as well as study nurses, and other study-related staff were addressed. The answers were analyzed using the Survio analyzing tool (http://www.survio.com/de/.ResultsWe collected 42 complete sets of answers; in total 28 physicians, 11 study nurses, and 3 persons with positions in administration answered our survey. The study centers reported to participate in a range of 3–160 clinical trials with a recruitment rate of 1–80%. Main obstacles were determined: 31/42 (74% complained about limited human resources and 22/42 (52% reported to have a lack on technical resources, too. 30/42 (71% consented to the answer, that the documentation

  3. German (GRS) approach to accident analysis (part I). German licensing basis for accident analyses. Applicants accident analyses in second part license for Konvoi-plants. Appendix 1. Assessor accident analyses in second part license for Konvoi-plants. Appendix 2. Reference list of DBA to be considered in the safety status analysis of a PSR. Appendix 3a. Reference list of special very rare and BDB plant conditions to be considered in the safety status analysis of a PSE. Appendix 3b

    Velkov, K.

    2002-01-01

    Appendix 1: The Safety Analysis Report (S.A.R.) is presented from 3 Handbooks - ECC Handbook (LOCA), Plant Dynamics Handbook (Transients incl. ATWS), and Core Design Handbook. The first one Conceived as Living handbook, Basis for design, catalogue of transients, specifications and licensing. Handbook contains LOCA in primary system, it contains also core damage analysis, and description of codes, description of essential plant data and code input data. The second one consists of Basis for design, commissioning, operation, and catalogue of transients, specifications and licensing, as well as specified operation, disturbed operation, incidents, non-LOCA, SS-procedures and Code description. The third book consists of Reactivity balance and reactivity coefficients, efficiency of shutdown systems. Calculation of burn up cycle, power density distribution, and critical boron concentration. Also Codes used, as SAV79A standard analysis methodology including FASER for nuclear data generation, MEDIUM and PANBOX for static and transient core calculations. Appendix 2: The three TUEV (Technical Inspection Agencies) responsible for the three individual plants of type KONVOI: TUEV Bayern for ISAR-2, TUV-Hanover for KKE, TUEV-Stuttgart for GKN-2 and GRS performed the safety assessment. TUV-Bayern for disturbance and failure of secondary heat sink without loss of coolant (failure of main heat sink, erroneous operation of valves in MS and in FW system, failure of MFW supply), long term LONOP, performance of selected SBLOCA analyses. TUV Hanover for disturbances due to failure of MCPs, short term LONOP, damages of SG tubes incl. SGTR, performance of selected LOCA analyses (blowdown phase of LBLOCA). TUV-Stuttgart for breaks and leaks in MS and FW system with and without leaks in SG tubes. GRS for ATWS, sub-cooling transients due to disturbances on secondary side, initial and boundary conditions for transients with opening of pressurizer valves with and without stuck-open, most of the

  4. 1999 Nuclear power world report

    Wesselmann, C.

    2000-01-01

    annual electricity generation by individual plants is concerned, the German Isar-2 nuclear power station was world champion in 1999 with an output of 12.268.287 Mwh. (orig.)

  5. Protection of quality and innovation in radiation oncology: The prospective multicenter trial the German Society of Radiation Oncology (DEGRO-QUIRO study). Evaluation of time, attendance of medical staff, and resources during radiotherapy with IMRT

    Vorwerk, H.; Schiller, R. [University of Marburg, Department of Radiotherapy and Radiooncology, Marburg (Germany); Zink, K.; Engenhart-Cabillic, R. [University of Marburg, Department of Radiotherapy and Radiooncology, Marburg (Germany); University of Giessen, Department of Radiotherapy and Radiooncology, Giessen (Germany); Budach, V.; Boehmer, D. [Charite, University of Berlin, Department of Radiotherapy and Radiooncology, Berlin (Germany); Kampfer, S. [Technische Universitaet Muenchen, Department of Radiation-Oncology, Muenchen (Germany); Popp, W. [Prime Networks AG, Basel (Switzerland); Sack, H. [University of Essen, Department of Radiotherapy and Radiooncology, Essen (Germany)

    2014-05-15

    A number of national and international societies published recommendations regarding the required equipment and manpower assumed to be necessary to treat a number of patients with radiotherapy. None of these recommendations were based on actual time measurements needed for specific radiotherapy procedures. The German Society of Radiation Oncology (DEGRO) was interested in substantiating these recommendations by prospective evaluations of all important core procedures of radiotherapy in the most frequent cancers treated by radiotherapy. The results of the examinations of radiotherapy with intensity-modulated radiation therapy (IMRT) in patients with different tumor entities are presented in this manuscript. Four radiation therapy centers [University Hospital of Marburg, University Hospital of Giessen, University Hospital of Berlin (Charite), Klinikum rechts der Isar der Technischen Universitaet Muenchen] participated in this prospective study. The workload of the different occupational groups and room occupancies for the core procedures of radiotherapy were prospectively documented during a 2-month period per center and subsequently statistically analyzed. The time needed per patient varied considerably between individual patients and between centers for all the evaluated procedures. The technical preparation (contouring of target volume and organs at risk, treatment planning, and approval of treatment plan) was the most time-consuming process taking 3 h 54 min on average. The time taken by the medical physicists for this procedure amounted to about 57 %. The training part of the preparation time was 87 % of the measured time for the senior physician and resident. The total workload for all involved personnel comprised 74.9 min of manpower for the first treatment, 39.7 min for a routine treatment with image guidance, and 22.8 min without image guidance. The mean room occupancy varied between 10.6 min (routine treatment without image guidance) and 23.7 min (first

  6. Radio(chemo)therapy for locally advanced squamous cell carcinoma of the esophagus. Long-term outcome

    Ordu, Arif Deniz; Deymann, Lisa Felicia; Scherer, Vera; Combs, Stephanie E. [Technische Universitaet Muenchen, Department of Radiation Oncology, Klinikum rechts der Isar, Muenchen (Germany); Nieder, Carsten [University of Tromsoe, Department of Oncology and Palliative Medicine, Nordland Hospital Trust, Bodoe (Norway); Institute of Clinical Medicine, Faculty of Health Sciences, Tromsoe (Norway); Geinitz, Hans [Technische Universitaet Muenchen, Department of Radiation Oncology, Klinikum rechts der Isar, Muenchen (Germany); Krankenhaus der Barmherzigen Schwestern Linz, Department of Radiation Oncology, Linz (Austria); Kup, Philipp Guenther [Marien Hospital Herne, Universitaetsklinikum der Ruhr-Universitaet Bochum, Department of Radiation Oncology, Herne (Germany); Fakhrian, Khashayar [Technische Universitaet Muenchen, Department of Radiation Oncology, Klinikum rechts der Isar, Muenchen (Germany); Marien Hospital Herne, Universitaetsklinikum der Ruhr-Universitaet Bochum, Department of Radiation Oncology, Herne (Germany); Universitaetsklinikum der Ruhr-Universitaet Bochum, Department of Radiation Oncology, Sankt Josef Hospital Bochum, Bochum (Germany)

    2014-11-18

    The purpose of this work is to report the long-term outcomes of three-dimensional conformal radio(chemo)therapy in the curative management of esophageal squamous cell carcinoma (ESCC). A retrospective analysis of patients treated with radio(chemo)therapy between 1988 and 2011 at Klinikum rechts der Isar, Technische Universitaet Muenchen was performed. In all, 168 patients received radio(chemo)therapy for ESCC in curative intention. The median follow-up time was 91 months (range 1-212 months). There were 128 men and 40 women with a median age of 63 years. Selection criteria for radio(chemo)therapy were unfit for surgery and/or unresectable primary tumor (n = 146, 87 %) or patients' choice (n = 22, 13 %). The majority of the patients received a combination of cisplatin and 5-fluorouracil chemotherapy with 54 Gy in 30 fractions of radiotherapy. The median overall survival (OS) was 20 months (95 % confidence interval 17-23 months). The OS at 2 and 5 years for the whole cohort was 41 ± 4 % and 22 ± 3 %, respectively. Forty patients (24 %) suffered an in-field recurrence. The most common acute nonhematologic toxicity >grade 2 was dysphagia in 35 % of the patients. Acute hematologic toxicity > grade 2 was recorded in 14 % of the patients. There was no grade 5 toxicity observed during the study. Poor ECOG performance status (0-1 vs. 2-3, HR = 1.70, p = 0.002) and weight loss ≥ 10 % before the start of therapy (HR = 1.99, p = 0.001) were among the factors significantly associated with poor OS in multivariate analysis. Three-dimensional conformal definitive radio(chemo)therapy is well tolerated and leads to long-term survival in more than 20 % of patients with advanced disease and/or contraindication to surgery. However, 24 % in-field recurrence remains a major concern. Prospective trials are warranted to assess if a well-tailored conformal radiochemotherapy can improve the local control and obviate the need for surgical resection in patients with good general

  7. Expert report of ENSI on the request of EKKB AG for a general license - Project 'New nuclear power plant to replace the Beznau plant'

    2010-09-01

    The 'Ersatz Kernkraftwerk Beznau AG' (EKKB) Company submitted to the Swiss Federal Inspectorate of Nuclear Safety (ENSI) a request for a general license for a new power plant to be built near to the Beznau power plants. According to the law, all damage risks with a probability higher than 10 -4 /a must be taken into account through protection measures. The considered risks concern the power plant itself as well as the population in the neighbourhood and the environment. The purpose of the general license is to demonstrate that the site chosen for the foreseen power plant is acceptable and that the risks can be counteracted through adequate measures. The buildings of the power plant and their partition on the Beznau Island in the Aare River are briefly described. The reactor is a Light Water Reactor of third generation with a maximum electrical power of 1450 MW el ±20%. The main cooling is provided by a hybrid system of water evaporation and air heating, what reduces the plume at the exit of the cooling tower. First, it is demonstrated that, in the case of a very unlikely severe accident in the power plant, the people in the neighbourhood can be evacuated quickly. Then, numerous types of possible accidents in the neighbourhood of the power plant are analyzed in order to settle their possible negative influence on the operation of the power plant: bursting of gas containers on the neighbouring roads and railways, fires of all types of hydrocarbons, air pollution through chloride gas, etc. The check by ENSI of the EKKB studies on the potential danger for the power plant through neighbouring industrial plants, roads or railways demonstrated that none of the considered accidents presents an unacceptable risk for the power plant: on the one hand, these plants are located too far from the power plant, so that a sensible injury to the power plant safety can be excluded; on the other, the protection of the power plant can be guaranteed through appropriate technical

  8. Expert report of ENSI on the request of KKN AG for a general license - Project 'New nuclear power plant Niederamt'

    2010-09-01

    The 'Kernkraftwerk Niederamt AG' (KKN) Company submitted to the Swiss Federal Inspectorate of Nuclear Safety (ENSI) a request for a general license for a new power plant to be built near to the Goesgen power plant. According to the law, all damage risks with a probability higher than 10 -4 /a must be taken into account through protection measures. The considered risks concern the power plant itself as well as the population in the neighbourhood and the environment. The purpose of the general license is to demonstrate that the site chosen for the foreseen power plant is acceptable and that the risks can be counteracted through adequate measures. The buildings of the power plant and their partition over the two banks of the Aare River are briefly described. The reactor is a Light Water Reactor of third generation with a maximum thermal power of 5.8 GW th . The main cooling is provided by a hybrid system of water evaporation and air heating, what reduces the plume at the exit of the cooling tower. First, it is demonstrated that, in the case of a very unlikely severe accident in the power plant, the people in the neighbourhood can be evacuated quickly. Then, numerous types of possible accidents in the neighbourhood of the power plant are analyzed in order to settle their possible negative influence on the operation of the power plant: bursting of gas containers on the neighbouring roads and railways, fires of all types of hydrocarbons, air pollution through chloride gas, etc. The check by ENSI of the KKN studies on the potential danger for the power plant through neighbouring industrial plants, roads or railways demonstrated that none of the considered accidents presents an unacceptable risk for the power plant: on the one hand, these plants are located too far from the power plant, so that a sensible injury to the power plant safety can be excluded; on the other, the protection of the power plant can be guaranteed through appropriate technical measures. The power

  9. Expert report of ENSI on the request of EKKM AG for a general license - Project 'New nuclear power plant to replace the Muehleberg plant'; Gutachten des ENSI zum Rahmenbewilligungsgesuch der EKKM AG. Neubauprojekt Ersatzkernkraftwerk Muehleberg

    NONE

    2010-09-15

    The 'Ersatz Kernkraftwerk Muehleberg AG' (EKKM) Company submitted to the Swiss Federal Inspectorate of Nuclear Safety (ENSI) a request for a general license for a new power plant to be built near to the Muehleberg power plant. According to the law, all damage risks with a probability higher than 10{sup -4}/a must be taken into account through protection measures. The considered risks concern the power plant itself as well as the population in the neighbourhood and the environment. The purpose of the general license is to demonstrate that the site chosen for the foreseen power plant is acceptable and that the risks can be counteracted through adequate measures. The buildings of the power plant and their partition on the left side of the Aare River are briefly described. The reactor is a Light Water Reactor of third generation with a maximum electrical power of 1.6 GW{sub el}. The European Pressurized water Reactor, which is of the same power class, can be taken as an example for planning that will follow. The main cooling is provided by one or, if needed, two cooling towers using a hybrid system of water evaporation and air heating, what reduces the plume at the exit of the cooling towers. The population density in the neighbourhood of the power plant is low; it is demonstrated that, in the case of a very unlikely severe accident in the power plant, the people in the neighbourhood can be evacuated quickly. Then, numerous types of possible accidents in the neighbourhood of the power plant are analyzed in order to settle their possible negative influence on the operation of the power plant: bursting of gas containers on the neighbouring roads and railways, fires of all types of hydrocarbons, air pollution through chloride gas, etc. The check by ENSI of the EKKM studies on the potential danger for the power plant through neighbouring industrial plants, roads or railways demonstrated that none of the considered accidents presents an unacceptable risk for the

  10. Expert report of ENSI on the request of EKKB AG for a general license - Project 'New nuclear power plant to replace the Beznau plant'; Gutachten des ENSI zum Rahmenbewilligungsgesuch der EKKB AG. Neubauprojekt Ersatzkernkraftwerk Beznau

    NONE

    2010-09-15

    The 'Ersatz Kernkraftwerk Beznau AG' (EKKB) Company submitted to the Swiss Federal Inspectorate of Nuclear Safety (ENSI) a request for a general license for a new power plant to be built near to the Beznau power plants. According to the law, all damage risks with a probability higher than 10{sup -4}/a must be taken into account through protection measures. The considered risks concern the power plant itself as well as the population in the neighbourhood and the environment. The purpose of the general license is to demonstrate that the site chosen for the foreseen power plant is acceptable and that the risks can be counteracted through adequate measures. The buildings of the power plant and their partition on the Beznau Island in the Aare River are briefly described. The reactor is a Light Water Reactor of third generation with a maximum electrical power of 1450 MW{sub el} {+-}20%. The main cooling is provided by a hybrid system of water evaporation and air heating, what reduces the plume at the exit of the cooling tower. First, it is demonstrated that, in the case of a very unlikely severe accident in the power plant, the people in the neighbourhood can be evacuated quickly. Then, numerous types of possible accidents in the neighbourhood of the power plant are analyzed in order to settle their possible negative influence on the operation of the power plant: bursting of gas containers on the neighbouring roads and railways, fires of all types of hydrocarbons, air pollution through chloride gas, etc. The check by ENSI of the EKKB studies on the potential danger for the power plant through neighbouring industrial plants, roads or railways demonstrated that none of the considered accidents presents an unacceptable risk for the power plant: on the one hand, these plants are located too far from the power plant, so that a sensible injury to the power plant safety can be excluded; on the other, the protection of the power plant can be guaranteed through

  11. Complementary and alternative medicine in radiation oncology. Survey of patients' attitudes

    Lettner, Sabrina [Technische Universitaet Muenchen (TUM), Department of Radiation Oncology, Muenchen (Germany); Kessel, Kerstin A.; Combs, Stephanie E. [Technische Universitaet Muenchen (TUM), Department of Radiation Oncology, Muenchen (Germany); Helmholtz Zentrum Muenchen, Institute of Innovative Radiotherapy (iRT), Neuherberg (Germany)

    2017-05-15

    bereits einen Vorteil gegenueber Standardtherapien. Ziel war die Erfassung der meist gewaehlten CAM, ihr Stellenwert sowie die generelle Akzeptanz bei radioonkologischen Patienten. Ein Fragebogen mit 18 Fragen, basierend auf der kategorischen Einteilung des National Center for Complementary and Integrative Health, wurde entwickelt. Alle Patienten, die zwischen April und September 2015 an der Klinik fuer RadioOnkologie und Strahlentherapie des Klinikums rechts der Isar eine Strahlentherapie (RT) erhalten hatten, wurden evaluiert. Akzeptanzaenderungen der Patienten hinsichtlich CAM wurden mit einem weiteren Fragebogen nach RT bei der ersten Nachsorgeuntersuchung ermittelt (n = 31). Von 634 Patienten beantworteten 333 (52,5 %) den Fragebogen. Von allen Befragten nutzten 39,3 % CAM vor RT und 26,4 % waehrend RT. Die haeufigsten Methoden waren Vitamine/Mineralstoffe, Nahrungsergaenzungsmittel, Physiotherapie/Manuelle Medizin und Homoeopathie. Die Mehrheit (71,5 %) verneinte eine parallel laufende CAM. Grund dafuer war bei 73,5 % aller Befragten das fehlende Angebot seitens der Aerzte. Beweggruende fuer den CAM-Gebrauch waren das Immunsystem zu verbessern (43,8 %), Therapienebenwirkungen zu verringern (43,8 %) und keine Chance auszulassen (37,8 %). Eine in das Therapiekonzept integrierte Behandlung wie z. B. Akupunktur wuerden 63,7 % (212/333) der RT-Patienten in Anspruch nehmen. Im Studienvergleich zeigte sich, dass der CAM-Einsatz parallel zur RT an unserer Klinik gering ist. Eine Patientenakzeptanz ist vorhanden, da etwa zwei Drittel eine in das individuelle Therapiekonzept integrierte CAM nutzen wuerden. (orig.)

  12. Avaliação de contratos: uma abordagem utilizando a Análise Fatorial de Correspondência

    Weimar Freire da Rocha Junior

    2008-06-01

    statistic multivariate method, which is going to assess nine contracts mostly consonant with the agribusiness (five contracts on sales, three on franchising and one on agriculture joint venture. These relationships facilitate to emphasize which are the main fears of the economic agents when they not only make contractual relationship among them but also what is/are the transaction attribute(s implicit in the established contracts. As a result, it was also observed the purchase and sale contracts of sugar cane (two, franchising of beverages, concrete made products, language schools and agriculture joint venture which are more linked to the specific commodities. Purchase and sale contract of sugar cane (one, manioc and sugar cane (three direct to a frequency. Purchase and sale contracts of soybean are inclined to be more uncertain.

  13. The Normality of EU Sport Policy Studies: Disciplinary Locus in Political Science, Sport Science or Elsewhere?

    Jacob Kornbeck

    2014-05-01

    Full Text Available The Normality of EU Sport Policy Studies: Disciplinary Locus in Political Science, Sport Science or Elsewhere? Mainstream European integration research has shown that research on the EU tends to follow the conjunctures of European integration itself. This realisation has led to some debate on which branch of political science – international relations or government – or indeed other academic disciplines is/are the most appropriate locus for such research. The paper takes these debates one step further by looking at the occurrence of ‘EU & sport’ studies within the wider field of EU studies. The main material used comes from the ECLAS database. Findings lead to a discussion of whether ‘EU & sport’ studies should rather be for EU specialists or for sport specialists and a plea for disciplinary normalisation whereby sport science would need to get more directly involved (without necessarily overwriting political science. Some ideas are added regarding the need for a mapping of Central & Eastern European scholarship. Normalita politických studií EU v oblasti sportu: místo v oborech politologie, sportovních vědách či jinde? Hlavní integrační proudy v evropském výzkumu dokumentují, že výzkum v EU má tendenci zkoumat evropskou integraci jako takovou. Toto poznání vedlo k diskusi, v kterém oboru politologie – mezinárodní vztahy či vláda – nebo i v jiných akademických disciplínách je nejvhodnější místo pro takový výzkum. Stať se pokouší posunout tyto diskuse o krok dále tím, že studie o „EU a sportu“ se posuzují v širším záběru EU studií. Hlavní informační zdroje pocházejí z databáze ECLAS. Naše zjištění vedou k diskusi o problematice „EU a sportu“ v tom smyslu, zda by tyto studie měly být spíše určeny odborníkům EU, nebo sportovním specialistům. Důležitá je otázka disciplinární začlenění této problematiky, s širším zapojením sportovních věd (aniž by

  14. Assessing gains in teacher knowledge and confidence in a long-duration climate literacy initiative

    Haine, D. B.; Kendall, L.; Yelton, S.

    2013-12-01

    Climate Literacy: Integrating Modeling & Technology Experiences (CLIMATE) in NC Classrooms, an interdisciplinary, global climate change program for NC high school science teachers is administered by UNC Chapel Hill's Institute for the Environment (IE) with funding from NASA's Innovations in Climate Education (NICE) Program. Currently in its third year, this year-long program serves 24 teaching fellows annually and combines hands-on climate science investigations with experiential learning in fragile ecosystem environments to achieve the following program goals: increased teacher knowledge of climate change science and predicted impacts; increased teacher knowledge of modeling and technology resources, with an emphasis on those provided by NASA; and increased teacher confidence in using technology to address climate change education. A mixed-methods evaluation approach that includes external evaluation is providing quantitative and qualitative data about the extent to which program goals are being achieved. With regard to increases in teacher knowledge, teachers often self-report an increase in knowledge as a result of a program activity; this session will describe our strategies for assessing actual gains in teacher knowledge which include pre- and post-collaborative concept mapping and pre- and post-open response questionnaires. For each evaluation approach utilized, the process of analyzing these qualitative data will be discussed and results shared. For example, a collaborative concept mapping activity for assessment of learning as a result of the summer institute was utilized to assess gains in content knowledge. Working in small groups, teachers were asked to identify key vocabulary terms and show their relationship to one another via a concept map to answer these questions: What is global climate change? What is/are the: evidence? mechanisms? causes? consequences? Concept maps were constructed at the beginning (pre) and again at the end (post) of the Summer

  15. EDITORIAL: The 18th Central European Workshop on Quantum Optics The 18th Central European Workshop on Quantum Optics

    Sánchez-Soto, Luis L.; Man'ko, Margarita A.

    2012-02-01

    decided that Physica Scripta could offer a poster prize (200 euros + certificate) for young scientists (less than 30 years old) at the annual CEWQO conference. A panel of experts was formed to judge the posters which included Apostol Vourdas, University of Bradford, UK (Chairman), Alberto Ibort, University Carlos III of Madrid, Spain, Andrei Klimov, University of Guadalajara, Mexico, Margarita A Man'ko, P N Lebedev Physical Institute, Moscow, Russia and Antonino Messina, University of Palermo, Italy. The poster ''How can we check the uncertainty relation?'' by Vladimir Chernega, PhD student of the P N Lebedev Physical Institute, won the prize. The 19th Central European Workshop on Quantum Optics will be held in Sinaia, Romania on 2-6 July 2012. It will be chaired by Professor Aurelian Isar from the Horia Hulubei National Institute for Research and Development in Physics and Nuclear Engineering, Bucharest.

  16. EDITORIAL The 17th Central European Workshop on Quantum Optics

    Man'ko, Margarita A.

    2011-02-01

    ), held at the University of Turku, are also available (2010 Phys. Scr. T140). The 18th Central European Workshop on Quantum Optics (CEWQO11) will be held in Madrid, Spain on 30 May--3 June 2011. It will be chaired by Professor Luis Lorenzo Sanchez Soto from the Complutense University of Madrid. List of Papers The 17th Central European Workshop on Quantum Optics in St Andrews, Scotland Ulf Leonhardt and Natalia Korolkova Double self-Kerr scheme for optical Schrödinger-cat state preparation P Adam, Z Darázs, T Kiss and M Mechler Relations between scaling transformed Husimi functions, Wigner functions and symplectic tomograms describing corresponding physical states V A Andreev, D M Davidović, L D Davidović and M D Davidović Entanglement dynamics of two independent cavity-embedded quantum dots B Bellomo, G Compagno, R Lo Franco, A Ridolfo and S Savasta Dynamical stabilization of spin systems in time-dependent magnetic fields Yu V Bezvershenko, P I Holod and A Messina Entanglement dynamics of a bipartite system in squeezed vacuum reservoirs Smail Bougouffa and Awatif Hindi On Wheeler's delayed-choice Gedankenexperiment and its laboratory realization M Božić, L Vušković, M Davidović and Á S Sanz A smooth, holographically generated ring trap for the investigation of superfluidity in ultracold atoms Graham D Bruce, James Mayoh, Giuseppe Smirne, Lara Torralbo-Campo and Donatella Cassettari Parametric amplification of the classical field in cavities with photoexcited semiconductors V V Dodonov Mutually unbiased bases: tomography of spin states and the star-product scheme S N Filippov and V I Man'ko Quantum trajectory model for photon detectors and optoelectronic devices Teppo Häyrynen, Jani Oksanen and Jukka Tulkki Entanglement in two-mode continuous variable open quantum systems Aurelian Isar A classical field comeback? The classical field viewpoint on triparticle entanglement Andrei Khrennikov Experimental investigation of the enhancement factor and the cross

  17. 2002年召开的部分国际地学会议

    黎明

    2002-01-01

    地震工程国际会议 波斯顿 (美国) eeri@ai.org 7月21~25日 第9届铂国际会议 蒙大拿 (美国) www.platinumsymposium.org/ 7月21~26日 第65届气象学会会议 洛杉矶 (美国) www.lpi.usra.edu/meetings/upcoming meetings.htm 7月22~26日 第3届水资源与环境研究国际会议--模拟与 生态系统管理中的水质量和质量影响 德累斯顿 (德国) www.tudresden.de/fghhihm/hydrologie.gie.html 7月22~26日 第11届国际矿床成因协会与2002年地质会议 温得和克 (纳米尼亚) www.geoconference2002.com/ 8月11~15日 第4届环境岩土力学国际会议 里约热内卢 (巴西) 4iceg.ufrij.br 8月18~23日 第12届戈尔德施密特年会 达沃斯 (瑞士) www.goldchmidt-conference.com/gold 2002/ 8月25~30日 冈瓦纳11:对比与连接国际会议 克赖斯特彻奇 (新西兰) www.anta.canterbury.acn2 8月26~31日 第6届特提斯海国际研讨会 布达佩斯 (匈牙利) pangea.elte.hu/padeo/tethys/index.htm 8月29~9月2日 第6届欧洲古植物学-孢粉学会议 雅典 (希腊) www.geol.uoa.gr/conference/ 9月1~6日 新千年矿物学会议 爱丁堡 (苏梅兰) www.minersoc.org/IMA2002 9月9~13日 第12届欧洲地震工程会议 伦敦 (英国) www.12ecee.org.uk 9月10~11日 铀矿床成因及其对环境的影响国际会议 布拉格 (捷克) jzeman@sci.muni.cz 9月12~22日 第6届侏罗系国际研讨会 巴勒莫 (意大利) martire@dst.unito.it 9月14~18日 AESE与EASE联合会议与第36届AESE年会 哈利法克斯 (加拿大) www.aese.org 9月15~19日 铀矿与水文学会议 弗赖贝格 (德国) www.geotufreiberg.de/umh 9月16~20日 第9届国际工程地质学与环境协会(IAEG)--发展中国家的工程地质学会议 德班 (南非) home.geoscience.org.za/saieg/2002.htm 9月22~26日 第4届人工补给、可持续含水层补给国际研讨会 阿德莱德 (澳大利亚) www.groundwater.com.au/conf/ISAR4.htm 9月22~27日 第7届地质综合国际会议 尼斯 (法国) www.78icg-nice 2002

  18. PREFACE: CEWQO Topical Issue CEWQO Topical Issue

    Bozic, Mirjana; Man'ko, Margarita

    2009-09-01

    vacuum may generate atom-atom entanglement. Dömötör et al elucidate a connection between entanglement and coherent states. Earlier they proved that in the symmetric subspace of a system of N qubits a pure state is not globally entangled, if and only if, it is a coherent state. Here they extend this proof to a system of N 'quKits' (subsystems of arbitrary finite dimension K). Napoli et al compute exactly localizable entanglement as a function of temperature for the system of three interacting spins in a thermal state. Isar considers entanglement in open quantum dynamics by studying the system of two independent oscillators interacting with the general environment. He proposes some special parameters of the environment that manifest interesting properties (e.g., the environment is entangling initially separable states). Lindén et al study the decay of entanglement in rings of qubits that live in the Markov environment. They use the entanglement of formation as the measure whose time evolution announces (or not) the decay. Jivulescu et al consider the time evolution of a spin-1/2 particle nonuniformly coupled through the Heisenberg interaction to the environment composed of N spins. Considering arbitrary initial conditions the authors determine a numerically manipulative general solution from which information on full dynamics may be extracted. Ferraro et al investigate the entanglement evolution of two qubits interacting with a common environment through a Heisenberg XX mechanism and show that the phenomena of entanglement hidden death and entanglement hidden revival take place. Stochastic processes have been very important in quantum optics. Pascazio et al review and compare three algorithms for the generation of sequences of symmetric stable Levy random variables. They draw conclusions on the efficiency of the algorithms used and on some applications in quantum optics. Hul et al report on the possibilities of explaining the statistical properties of the spectra of