77 FR 14461 - Approval of Noise Compatibility Program for W.K. Airport, Battle Creek, MI

Science.gov (United States)

2012-03-09

....K. Kellogg Airport noise compatibility program. All of the recommendations of the program were... Noise Compatibility Program for W.K. Kellogg Airport is February 16, 2012. FOR FURTHER INFORMATION... the Noise Compatibility Program for W.K. Kellogg Airport, effective February 16, 2012. Under section...

A 2-wk reduction of ambulatory activity attenuates peripheral insulin sensitivity

DEFF Research Database (Denmark)

Krogh-Madsen, Rikke; Thyfault, John P; Broholm, Christa

2010-01-01

decreased after step reduction, with a post hoc analysis revealing the most pronounced effect after 4 h of insulin infusion. In addition, the 2-wk period induced a 7% decline in VO2 max (ml/min; cardiovascular fitness). Lean mass of legs, but not arms and trunk, decreased concurrently. Taken together, one...... possible biological cause for the public health problem of Type 2 diabetes has been identified. Reduced ambulatory activity for 2 wk in healthy, nonexercising young men significantly reduced peripheral insulin sensitivity, cardiovascular fitness, and lean leg mass........ A reduced number of daily steps induced a significant reduction of 17% in the glucose infusion rate (GIR) during the clamp. This reduction was due to a decline in peripheral insulin sensitivity with no effect on hepatic endogenous glucose production. The insulin-stimulated ratio of pAktthr308/total Akt...

“If You Don’t Bring No Grits, Don’t Come”: Critiquing a Critique of Patrick Kelly, Golliwogs, And Camp as A Technique of Black Queer Expression

Directory of Open Access Journals (Sweden)

Barnes Sequoia

2017-12-01

Full Text Available I have written this article in order to establish Patrick Kelly as a black forbearer of fashion. Kelly complicates our sense of fashion through his use of black memorabilia and camp to not only create something consumable but to comment on the black body as a consumable. Therefore, the role I play in acknowledging this black supernova, as Eric Darnell Pritchard calls him, is by critiquing Lewis and Fraley’s critique of Patrick Kelly and questioning why overtly expressing one’s queerness through camp has not been seen as a viable form of black expression in the mainstream narrative of black creativity. Lewis and Fraley’s complete dismissal of Kelly’s use of camp does not happen in a vacuum. Yet, I must remember that there is also the task of establishing a legacy of technique for Patrick Kelly. Who are his forbearers?

75 FR 28295 - Federal-Mogul, Including On-Site Leased Workers From Kelly Services, Summerton, SC; Amended...

Science.gov (United States)

2010-05-20

... workers were sufficiently under the control of the subject firm to be considered leased workers. Based on... On-Site Leased Workers From Kelly Services, Summerton, SC; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In accordance with Section 223 of the Trade Act of 1974...

Medical Movies on the Web Debuts with Gene Kelly's "Combat Fatigue Irritability" 1945 Film | NIH MedlinePlus the ...

Science.gov (United States)

... National Library of Medicine (NLM) is a World War II U.S. Navy training film directed by and starring Gene Kelly, who was then a rising Hollywood star. Combat Fatigue Irritability is a historically significant, yet ...

Preliminary factor analysis of the O’Kelly Women Beliefs Scale in a US sample

Directory of Open Access Journals (Sweden)

Arturo Heman Contreras

2012-06-01

Full Text Available Using a Rational Emotive Behavior Therapy framework, the O’Kelly Women Beliefs Scale (O’Kelly, in press was originally constructed in Australia to measure sex-role beliefs women may develop through sex-role stereotyping. Factor analysis of the 92 original items showed that 64 items loaded into a single component that accounted for 18.2% of the variance in a sample of 974 Australian women. The present exploratory study examined the psychometric properties of the OWBS in a sample of 202 women born and living in the US. A varimax rotation with cutoff eigenvalues of 3, showed that 37 items loaded into 3 components which accounted for 58.48% of the variance. The items were subsequently grouped into two factors: Ir- rationality, with a total of 27 items was created by merging component 1 and 3 (Pearson’s r = 0.8 between them, and Rationality, with the 10 items from component 2. Analyses indicated a Cronbach’s alpha of 0.91 for Fac- tor 1, and a Cronbach’s alpha 0.74 for Factor 2. Results indicate that this version of the instrument may be used to evaluate both the rational and irrational content of sex-role beliefs of women born in the US.

C. Walker-Said and J. D. Kelly (eds), Corporate Social Responsibility? Human Rights in the New Global Economy (Chicago, IL: The University of Chicago Press, 2015), 392 pp

DEFF Research Database (Denmark)

Whelan, Glen

2017-01-01

Book review of: Charlotte Walker-Said and John D. Kelly (eds), Corporate Social Responsibility? Human Rights in the New Global Economy (Chicago, IL: The University of Chicago Press, 2015), 392 pp.......Book review of: Charlotte Walker-Said and John D. Kelly (eds), Corporate Social Responsibility? Human Rights in the New Global Economy (Chicago, IL: The University of Chicago Press, 2015), 392 pp....

Should Community College Be Free? Forum. "Education Next" Talks with Sara Goldrick-Rab and Andrew P. Kelly

Science.gov (United States)

Goldrick-Rab, Sara; Kelly, Andrew P.

2016-01-01

In this article, "Education Next" talks with Sara Goldrick-Rab and Andrew Kelly. President Obama's proposal for tuition-free community college, seems to have laid down a marker for the Democratic Party. Vermont senator Bernie Sanders is touting his plan for free four-year public college on the primary trail; Massachusetts senator…

77 FR 9969 - Johnson Controls D/B/A Hoover Universal, Inc. Including On-Site Leased Workers from Kelly...

Science.gov (United States)

2012-02-21

... Johnson Controls, including on-site leased workers from Kelly Services, Sycamore, Illinois. The notice was... amended notice applicable to TA-W-73,074 is hereby issued as follows: ''All workers of Johnston Controls... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-73,074] Johnson Controls D/B/A...

STS-114: Crew Interviews: 1. Jim Kelly 2. Charlie Camarda

Science.gov (United States)

2005-01-01

1) STS-114 Pilot James Kelly mentions his primary job as the Pilot is to back up Commander Eileen Collins all through the flight. James discusses in detail his robotics operations for all of the extravehicular activities and spacewalk work, as well as moving the logistics module back and forth, onto the station and back in the payload bay. He shares his thoughts on the Columbia, the STS-114 mission as a new chapter in space exploration, and the International Space Station. 2) STS-114 Mission Specialist Charlie Camarda discusses his major role in the mission, his feelings for this being his first Space Shuttle flight; shares his thoughts on the Columbia; mentioned that STS-114 is a baby step to what is needed to do for the next step in space exploration, and gave some examples on how the International Space Station can help pave the path to future space exploration.

STS-103 Pilot Scott Kelly during TCDT activities

Science.gov (United States)

1999-01-01

STS-103 Pilot Scott J. Kelly is ready to take his turn at driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. Behind him (left) is Mission Specialist Jean-Frangois Clervoy of France, who is with the European Space Agency. At right is Mission Specialist Steven L. Smith. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr. and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland, who also is with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

Effect of vitamin A supplementation with BCG vaccine at birth on vitamin A status at 6 wk and 4 mo of age

DEFF Research Database (Denmark)

Fisker, Ane B; Lisse, Ida M; Aaby, Peter

2007-01-01

concentrations indicated vitamin A deficiency in 32% of the children at age 6 wk and in 16% at age 4 mo. VAS was not associated with higher RBP concentrations overall or in either sex. However, the effect of VAS varied with maternal education (P for interaction = 0.004): At age 6 wk, VAS was associated...... with higher (9%; 95% CI: 2, 17%) RBP concentrations in children of noneducated mothers but not in children of educated mothers. Overall, RBP concentrations increased between 6 wk and 4 mo of age. The increase correlated inversely with the number of diphtheria-tetanus-pertussis (DTP) vaccines received...... placebo-controlled trial of VAS, we obtained blood from 614 children at 6 wk of age and from 369 mother-infant pairs at 4 mo of age. We assessed vitamin A status on the basis of serum retinol-binding protein (RBP) and measured serum C-reactive protein to monitor for concurrent infections. RESULTS: RBP...

Cinema and the Great War - Andrew Kelly, 1997. History by Hollywood. The use and abuse of the American past - Robert Brant Toplin, 1996

NARCIS (Netherlands)

Kester, Bernadette

1998-01-01

textabstractReview of: Cinema and the Great War. Andrew Kelly, Londen, New York (Routledge), 1997, 219 p.History by Hollywood. The use and abuse of the American past. Robert Brant Toplin, Chicago (Urbana), 1996, 267 p.

Effects of 2 wk of GH administration on 24-h indirect calorimetry in young, healthy, lean men

DEFF Research Database (Denmark)

Hansen, Mette; Morthorst, Rikke; Larsson, Benny

2005-01-01

The present study was designed as a randomized, double-blind placebo (Plc)-controlled study to determine the effect of 2 wk of growth hormone administration (GH-adm.) on energy expenditure (EE) and substrate oxidation in healthy humans. Sixteen young healthy men were divided into two groups....... The study consisted of two 24-h measurements (indirect calorimetry), separated by 2 wk of either Plc or GH injections (6 IU/day). At baseline, no significant differences were observed between the two groups in any of the measured anthropometric, hormonal, or metabolic parameters, neither did the parameters...... change over time in the Plc group. GH-adm. resulted in a 4.4% increase in 24-h EE (P

Revisiting fracture gradient: Comments on “A new approaching method to estimate fracture gradient by correcting Matthew–Kelly and Eaton's stress ratio”

KAUST Repository

Hakiki, Farizal; Shidqi, Muizzuddin

2017-01-01

A study performed by Marbun et al. [1] claimed that “A new methodology to predict fracture pressure from former calculations, Matthew–Kelly and Eaton are proposed.” Also, Marbun et al.'s paper stated that “A new value of Poisson's and a stress ratio

Aculturación y diferencias en las creencias irracionales sobre el rol femenino tradicional (O'Kelly Women Beliefs Scale en mujeres colombianas residentes en su país de origen y en Estados Unidos

Directory of Open Access Journals (Sweden)

LEONOR LEGA

2009-01-01

Full Text Available La Escala de Creencias de las Mujeres de O'Kelly (O'Kelly Women Beliefs Scale., O'Kelly, en prensa; Ellis, 1958 fue aplicada a colombianas residentes en Cali, Colombia, colombianas residentes en el noreste de los Estados Unidos y sus contrapartes estadounidenses (20 madres y 20 hijas mayores de 17" años en cada grupo. Se encontró que existen diferencias transcultu- rales en los puntajes totales de los tres grupos. Comparaciones posthoc (LSD indicaron que las diferencias significativas seencuentran en las hijas colombianas residentes en Estados Unidos, comparadas con las madres colombianas residentes en Colombia y las madres e hijas estadounidenses. No existen diferencias entre madres e hijas colombianas residentes en Estados Unidos. Los resultados sugieren que el patrón de aculturación de los colombianos en los Estados Unidos es el de asimilación al país de adopción conservando aspectos de la tradición y la cultura del país de origen.

Concord grape juice, cognitive function, and driving performance: a 12-wk, placebo-controlled, randomized crossover trial in mothers of preteen children.

Science.gov (United States)

Lamport, Daniel J; Lawton, Clare L; Merat, Natasha; Jamson, Hamish; Myrissa, Kyriaki; Hofman, Denise; Chadwick, Helen K; Quadt, Frits; Wightman, JoLynne D; Dye, Louise

2016-03-01

Daily consumption of Concord grape juice (CGJ) over 3-4 mo has been shown to improve memory function in adults with mild cognitive impairment and reduce blood pressure in hypertensive adults. These benefits likely result from the high concentration of polyphenols in CGJ. Increased stress can impair cognitive function and elevate blood pressure. Thus, we examined the potential beneficial effect of CGJ in individuals with somewhat stressful and demanding lifestyles. We sought to examine the effects of the daily consumption of CGJ for 12 wk on cognitive function, driving performance, and blood pressure in healthy, middle-aged working mothers. Twenty-five healthy mothers (aged 40-50 y) of preteen children who were employed for ≥30 h/wk consumed 12 ounces (355 mL) of either CGJ (containing 777 mg total polyphenols) or an energy-, taste-, and appearance-matched placebo daily for 12 wk according to a randomized crossover design with a 4-wk washout. Verbal and spatial memory, executive function, attention, blood pressure, and mood were assessed at baseline and at 6 and 12 wk. Immediately after the cognitive battery, a subsample of 17 women completed a driving performance assessment at the University of Leeds Driving Simulator. The 25-min driving task required participants to match the speed and direction of a lead vehicle. Significant improvements in immediate spatial memory and driving performance were observed after CGJ relative to placebo. There was evidence of an enduring effect of CGJ such that participants who received CGJ in arm 1 maintained better performance in the placebo arm. Cognitive benefits associated with the long-term consumption of flavonoid-rich grape juice are not exclusive to adults with mild cognitive impairment. Moreover, these cognitive benefits are apparent in complex everyday tasks such as driving. Effects may persist beyond the cessation of flavonoid consumption, and future studies should carefully consider the length of washout within

Similar carbohydrate but enhanced lactate utilization during exercise after 9 wk of acclimatization to 5,620 m

DEFF Research Database (Denmark)

Van Hall, Gerrit; Calbet, J A L; Sondergaard, H

2002-01-01

We hypothesized that reliance on lactate as a means of energy distribution is higher after a prolonged period of acclimatization (9 wk) than it is at sea level due to a higher lactate Ra and disposal from active skeletal muscle. To evaluate this hypothesis, six Danish lowlanders (25 +/- 2 yr) were...... studied at rest and during 20 min of bicycle exercise at 146 W at sea level (SL) and after 9 wk of acclimatization to 5,260 m (Alt). Whole body glucose Ra was similar at SL and Alt at rest and during exercise. Lactate Ra was also similar for the two conditions at rest; however, during exercise, lactate Ra...... was substantially lower at SL (65 micro mol. min(-1). kg body wt(-1)) than it was at Alt (150 micro mol. min(-1). kg body wt(-1)) at the same exercise intensity. During exercise, net lactate release was approximately 6-fold at Alt compared with SL, and related to this, tracer-calculated leg lactate uptake...

Department of Clinical Investigation Annual Research Progress Report: Fiscal Year 1990

Science.gov (United States)

1990-09-30

Rawlings JS Hematol y Oncology 11(4): 395-401, 1989 Bower DJ Marlar RA Kelly PC Attention Deficit Disorders and Depression - Atkinson AW Reply. Pediatrics...Heparin 125 #90/35 Therapy in a Military Setting SOWRAY PC 0 Treatment of Thrombocytopenia, Hemolytic 126 #90/07 Anemia , or Neutropenia with Ascorbic...Induced Hypertension and Preeclampsia in Primigravida Women BRADY WK C Treatment of Bacterial Vaginosis in 151 #87/115 Pregnancy BROWNING JB 0

Effects on weight loss in adults of replacing diet beverages with water during a hypoenergetic diet: a randomized, 24-wk clinical trial.

Science.gov (United States)

Madjd, Ameneh; Taylor, Moira A; Delavari, Alireza; Malekzadeh, Reza; Macdonald, Ian A; Farshchi, Hamid R

2015-12-01

Obese people believe that drinking diet beverages (DBs) may be a simple strategy to achieve weight loss. However, nutritionists advise drinking water when attempting to lose weight. It is unclear how important drinking water instead of DBs is during a weight-loss program. In this study, we compared the effect on weight loss of either replacing DBs with water or continuing to consume DBs in adults during a 24-wk weight-loss program. Overweight and obese women [n = 89; body mass index (BMI; in kg/m(2)): 27-40; age: 18-50 y] who usually consumed DBs in their diet were asked to either substitute water for DBs (water group) or continue drinking DBs 5 times/wk after their lunch for 24 wk (DB group) while on a weight-loss program. Sixty-two participants (71%) completed the trial (32 in the DB group, 30 in the water group). Baseline variables were not statistically significantly different between groups. A statistically significant reduction in anthropometric measurements and statistically significant improvements in cardiometabolic risk characteristics were observed over 24 wk in both groups. Compared with the DB group, the water group had a greater decrease in weight (mean ± SD: water: -8.8 ± 1.9 kg; DBs: -7.6 ± 2.1 kg; P = 0.015, time × group), fasting insulin (mean ± SD: water: -2.84 ± 0.77 mU/L; DBs: -1.78 ± 1.25 mU/L, P water: -0.097 ± 0.049; DBs: -0.057 ± 0.042, P water: -1.02 ± 0.25 mmol/L; DBs: -0.72 ± 0.27 mmol/L; P fasting plasma glucose, and lipid profiles within both groups over 24 wk. Replacement of DBs with water after the main meal may lead to greater weight reduction during a weight-loss program. It may also offer clinical benefits to improve insulin resistance. This trial was registered at www.irct.ir/ as IRCT201402177754N5. © 2015 American Society for Nutrition.

The thermal regime and species composition of fish and invertebrates in Kelly Warm Spring, Grand Teton National Park, Wyoming

Science.gov (United States)

Harper, David; Farag, Aida

2017-01-01

We evaluated the thermal regime and relative abundance of native and nonnative fish and invertebrates within Kelly Warm Spring and Savage Ditch, Grand Teton National Park, Wyoming. Water temperatures within the system remained relatively warm year-round with mean temperatures >20 °C near the spring source and >5 °C approximately 2 km downstream of the source. A total of 7 nonnative species were collected: Convict/Zebra Cichlid (Cichlasoma nigrofasciatum), Green Swordtail (Xiphophorus hellerii), Tadpole Madtom (Noturus gyrinus), Guppy (Poecilia reticulata), Goldfish (Carassius auratus), red-rimmed melania snail (Melanoides tuberculata), and American bullfrog tadpoles (Lithobates catesbeianus). Nonnative fish (Zebra Cichlids and Green Swordtails), red-rimmed melania snails, and bullfrog tadpoles dominated the upper 2 km of the system. Abundance estimates of the Zebra Cichlid exceeded 12,000 fish/km immediately downstream of the spring source. Relative abundance of native species increased movingdownstream as water temperatures attenuated with distance from the thermally warmed spring source; however, nonnative species were captured 4 km downstream from the spring. Fish diseases were prevalent in both native and nonnative fish from the Kelly Warm Spring pond. Clinostomum marginatum, a trematode parasite, was found in native species samples, and the tapeworm Diphyllobothrium dendriticum was present in samples from nonnative species. Diphyllobothrium dendriticum is rare in Wyoming. Salmonella spp. were also found in some samples of nonnative species. These bacteria are associated with aquarium fish and aquaculture and are generally not found in the wild.

Developing a programmatic approach to investigating and remediating many unrelated comprehensive environmental response, compensation, and liability act sites at Kelly Air Force Base

International Nuclear Information System (INIS)

Kamp, G.; Regan, P.; Ninesteel, R.; Martin, R.

1988-01-01

Kelly Air Force Base (AFB), which was founded in 1917, is involved in logistics and maintenance activities supporting the Air Logistics Command. In addition, Kelly AFB hosts over 50 tenant organizations representing the Air Force, Department of Defense, and other government agencies. Over the years waste disposal from this complex was conducted in a manner that led to the identification of over 30 sites to be included in the Installation Restoration Program (IRP) after the Phase 1 investigation. A methodology was needed to prioritize the Remedial Investigations and Feasibility Study (RI/FS) activities for the sites. A Strategy Plan was developed that involved reviewing and interpreting existing data, identifying data voids relative to site specific RI/FS activities, and developing methodology to prioritize activities. Sites were prioritized, and a comprehensive IRP planning document was developed. One data deficiency was revealed -- the lack of understanding of the Basewide hydrogeologic conditions necessary to establish an effective restoration program. A Hydrogeologic Investigation was initiated to provide this data. This data will allow better interpretation of the interaction of the sites, particularly those in close proximity, and improved planning of remediation activities

The Effect of Divergent Selection on 4-wk BW on the Shape of Growth Curve in Japanese Quail

Directory of Open Access Journals (Sweden)

H Beyki

2011-12-01

Full Text Available The current study was conducted to investigate the effect of short-term divergent selection on the shape growth curve in different lines of Japanese quail. The Quail lines utilized in this study were two divergently selected for high (HW and low (LW 4-wk body weight during 7 generation and also a control line (C. The Richard function parameters were used to describe growth curves of different lines. The weight at hatch was approximately similar among lines (8.08 g, 7.55 g and 8.76 g for HW, LW and C line respectively. The results of current study indicated that the selected lines (HW & LW were immediately diverged from the C line after hatch. Sexes within each line had no difference in average growth rate, age and body weight at inflection point and adult body weight. However significant differences were found in the growth curve parameters among lines. The results of current study indicated that short term divergent selection for 4-wk BW in Japanese quail can change the growth pattern and the carcass compartments of the selected birds. Therefore to avoid undesirable side effects due to selection in Japanese quails it is recommended to consider the growth pattern changes of the selected birds in the breeding programs

ACULTURACIÓN Y DIFERENCIAS EN LAS CREENCIAS IRRACIONALES SOBRE EL ROL FEMENINO TRADICIONAL (O’ KELLY WOMEN BELIEFS SCALE EN MUJERES COLOMBIANAS RESIDENTES EN SU PAÍS DE ORIGEN Y EN ESTADOS UNIDOS

Directory of Open Access Journals (Sweden)

MARÍA TERESA PAREDES

2009-08-01

Full Text Available Normal 0 21 false false false MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} La Escala de Creencias de las Mujeres de O'Kelly (O'Kelly Women Beliefs Scale., O'Kelly, en prensa; Ellis, 1958 fue aplicada a colombianas residentes en Cali, Colombia, colombianas residentes en el noreste de los Estados Unidos y sus contrapartes estadounidenses (20 madres y 20 hijas mayores de 17 años en cada grupo. Se encontró que existen diferencias transculturales en los puntajes totales de los tres grupos. Comparaciones posthoc (LSD indicaron que las diferencias significativas se encuentran en las hijas colombianas residentes en Estados Unidos, comparadas con las madres colombianas residentes en Colombia y las madres e hijas estadounidenses. No existen diferencias entre madres e hijas colombianas residentes en Estados Unidos. Los resultados sugieren que el patrón de aculturación de los colombianos en los Estados Unidos es el de asimilación al país de adopción conservando aspectos de la tradición y la cultura del país de origen.

Pulmonary gas exchange at maximal exercise in Danish lowlanders during 8 wk of acclimatization to 4,100 m and in high-altitude Aymara natives

DEFF Research Database (Denmark)

Lundby, Carsten; Calbet, Jose A L; van Hall, Gerrit

2004-01-01

We aimed to test effects of altitude acclimatization on pulmonary gas exchange at maximal exercise. Six lowlanders were studied at sea level, in acute hypoxia (AH), and after 2 and 8 wk of acclimatization to 4,100 m (2W and 8W) and compared with Aymara high-altitude natives residing...... in AH but increased significantly with acclimatization (51 +/- 1.1, 58 +/- 1.7, and 62 +/- 1.6 mmHg in AH, 2W, and 8W, respectively). PaO2 in lowlanders reached levels that were not different from those in high-altitude natives (66 +/- 1.2 mmHg). Arterial O2 saturation (SaO2) decreased during maximum......, but even acclimatization for 8 wk is insufficient to achieve levels reached by high-altitude natives....

Broadband Photometry Of The Potentially Asteroid 277475 (2005 WK4) and Corrected 52762 (1998 MT24) Colors.

Science.gov (United States)

Hicks, M.; Buratt, B.; Carcione, A.; Borlase, R.

2013-08-01

The Near-Earth Object (NEO) 277475 (2005 WK4) was discovered by the Siding Spring Survey (MPEC 2005-W79) on November 27, 2005. With a Minimum Orbit Intersection Distance (MOID) of 0.004 AU and absolute magnitude H_V=20.1 mag, this object has been designated a Potentially Hazardous Asteroid (PHA) by the Minor Planet Center. The asteroid made an Earth close-approach of 0.021 AU on August 09.2, 2013 and was extensively imaged by the JPL Planetary Radar Team ( http://www.jpl.nasa.gov/news/news.php?release=2013-254 ).

Effect of vitamin A supplementation with BCG vaccine at birth on vitamin A status at 6 wk and 4 mo of age

DEFF Research Database (Denmark)

Fisker, Ane B; Lisse, Ida M; Aaby, Peter

2007-01-01

with higher (9%; 95% CI: 2, 17%) RBP concentrations in children of noneducated mothers but not in children of educated mothers. Overall, RBP concentrations increased between 6 wk and 4 mo of age. The increase correlated inversely with the number of diphtheria-tetanus-pertussis (DTP) vaccines received...

Effect of 2-wk intensified training and inactivity on muscle Na+-K+ pump expression, phospholemman (FXYD1) phosphorylation, and performance in soccer players.

Science.gov (United States)

Thomassen, Martin; Christensen, Peter M; Gunnarsson, Thomas P; Nybo, Lars; Bangsbo, Jens

2010-04-01

The present study examined muscle adaptations and alterations in performance of highly trained soccer players with intensified training or training cessation. Eighteen elite soccer players were, for a 2-wk period, assigned to either a group that performed high-intensity training with a reduction in the amount of training (HI, n = 7), or an inactivity group without training (IN, n = 11). HI improved (P Na(+)-K(+) pump alpha(2)-isoform was 15% higher (P Na(+)-K(+) pump expression was not changed. In HI, the FXYD1ser68-to-FXYD1 ratio was 27% higher (P Na(+)-K(+) pump alpha(2)-isoform expression, and that cessation of training for 2 wk does not affect the expression of Na(+)-K(+) pump isoforms. Resting phosphorylation status of the Na(+)-K(+) pump is changed by training and inactivity and may play a role in performance during repeated, intense exercise.

Revisiting fracture gradient: Comments on “A new approaching method to estimate fracture gradient by correcting Matthew–Kelly and Eaton's stress ratio”

KAUST Repository

Hakiki, Farizal

2017-07-25

A study performed by Marbun et al. [1] claimed that “A new methodology to predict fracture pressure from former calculations, Matthew–Kelly and Eaton are proposed.” Also, Marbun et al.\\'s paper stated that “A new value of Poisson\\'s and a stress ratio of the formation were generated and the accuracy of fracture gradient was improved.” We found those all statements are incorrect and some misleading concepts are revealed. An attempt to expose the method of fracture gradient determination from industry practice also appears to solidify that our arguments are acceptable to against improper Marbun et al.\\'s claims.

STS-103 Pilot Scott Kelly and MS John Grunsfeld try on oxygen masks

Science.gov (United States)

1999-01-01

In the bunker at Launch Pad 39B, STS-103 Pilot Scott J. Kelly (left) and Mission Specialist John M. Grunsfeld (Ph.D.) (right) try on oxygen masks during Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members taking part are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

Effects of a 6-wk intraduodenal supplementation with quercetin on energy metabolism and indicators of liver damage in periparturient dairy cows.

Science.gov (United States)

Stoldt, Ann-Kathrin; Derno, Michael; Nürnberg, Gerd; Weitzel, Joachim M; Otten, Winfried; Starke, Alexander; Wolffram, Siegfried; Metges, Cornelia C

2015-07-01

Periparturient dairy cows experience metabolic challenges that result in a negative energy balance (EB) and a range of postpartum health problems. To compensate for the negative EB, cows mobilize fatty acids from adipose tissues, which can lead to fatty liver disease, a periparturient metabolic disorder. Flavonoids, such as quercetin (Q), are polyphenolic substances found in all higher plants and have hepatoprotective potential and the ability to prevent or reduce lipid accumulation in the liver. In ruminants, few studies on the metabolic effects of Q are available, and thus this study was conducted to determine whether Q has beneficial effects on EB, lipid metabolism, and hepatoprotective effects in periparturient dairy cows. Quercetin was supplemented intraduodenally to circumvent Q degradation in the rumen. Cows (n=10) with duodenal fistulas were monitored for 7wk. Beginning 3wk before expected calving, 5 cows were treated with 100mg of quercetin dihydrate per kilogram of body weight daily in a 0.9% sodium chloride solution for a total period of 6wk, whereas the control cows received only the sodium chloride solution. The plasma flavonoid levels were higher in the Q-treated cows than in the control cows. A tendency for higher postpartum (pp) than antepartum (ap) plasma flavonoid levels was observed in the Q-treated cows than in the controls, which was potentially caused by a reduced capacity to metabolize Q. However, the metabolic status of the Q-treated cows did not differ from that of the control cows. The pp increases in plasma aspartate aminotransferase and glutamate dehydrogenase activities were less in the Q-treated cows than in the control cows. The Q had no effect on energy expenditures, but from ap to pp the cows had a slight decline in respiratory quotients. Irrespective of the treatment group, the oxidation of fat peaked after calving, suggesting that the increase occurred because of an increased supply of fatty acids from lipomobilization. In

"When does making detailed predictions make predictions worse?": Correction to Kelly and Simmons (2016).

Science.gov (United States)

2016-10-01

Reports an error in "When Does Making Detailed Predictions Make Predictions Worse" by Theresa F. Kelly and Joseph P. Simmons ( Journal of Experimental Psychology: General , Advanced Online Publication, Aug 8, 2016, np). In the article, the symbols in Figure 2 were inadvertently altered in production. All versions of this article have been corrected. (The following abstract of the original article appeared in record 2016-37952-001.) In this article, we investigate whether making detailed predictions about an event worsens other predictions of the event. Across 19 experiments, 10,896 participants, and 407,045 predictions about 724 professional sports games, we find that people who made detailed predictions about sporting events (e.g., how many hits each baseball team would get) made worse predictions about more general outcomes (e.g., which team would win). We rule out that this effect is caused by inattention or fatigue, thinking too hard, or a differential reliance on holistic information about the teams. Instead, we find that thinking about game-relevant details before predicting winning teams causes people to give less weight to predictive information, presumably because predicting details makes useless or redundant information more accessible and thus more likely to be incorporated into forecasts. Furthermore, we show that this differential use of information can be used to predict what kinds of events will and will not be susceptible to the negative effect of making detailed predictions. PsycINFO Database Record (c) 2016 APA, all rights reserved

Effects of pistachio nuts on body composition, metabolic, inflammatory and oxidative stress parameters in Asian Indians with metabolic syndrome: a 24-wk, randomized control trial.

Science.gov (United States)

Gulati, Seema; Misra, Anoop; Pandey, Ravindra Mohan; Bhatt, Surya Prakash; Saluja, Shelza

2014-02-01

The aim of this study was to evaluate the effects of pistachio nuts as an adjunct to diet and exercise on body composition, metabolic, inflammatory, and oxidative stress parameters in Asian Indians with metabolic syndrome. In this 24-wk randomized control trial, 60 individuals with the metabolic syndrome were randomized to either pistachio (intervention group) or control group (diet as per weight and physical activity profile, modulated according to dietary guidelines for Asian Indians) after 3 wk of a diet and exercise run in. In the first group, unsalted pistachios (20% energy) were given daily. A standard diet and exercise protocol was followed for both groups. Body weight, waist circumference (WC), magnetic resonance imaging estimation of intraabdominal adipose tissue and subcutaneous abdominal adipose tissue, fasting blood glucose (FBG), fasting serum insulin, glycosylated hemoglobin, lipid profile, high-sensitivity C-reactive protein (hs-CRP), adiponectin, free fatty acids (FFAs), tumor necrosis factor (TNF)-α, leptin, and thiobarbituric acid reactive substances (TBARS) were assessed before and after the intervention. Statistically significant improvement in mean values for various parameters in the intervention group compared with control group were as follows: WC (P pistachios leads to beneficial effects on the cardiometabolic profile of Asian Indians with metabolic syndrome. Copyright © 2014 Elsevier Inc. All rights reserved.

Effect of 2-wk intensified training and inactivity on muscle Na+/K+ pump expression, phospholemman (FXYD1) phosphorylation and performance in soccer players

DEFF Research Database (Denmark)

Thomassen, Martin; Christensen, Peter Møller; Gunnarsson, Thomas Gunnar Petursson

2010-01-01

The present study examined muscle adaptations and alterations in performance of highly trained soccer players with intensified training or training cessation. Eighteen elite soccer players were for a 2-wk period assigned to either a group which performed high intensity training with a reduction....... The present data suggest that short-term intensified training even for trained soccer players can increase muscle Na(+)/K(+) pump alpha2 isoform expression and that cessation of training for two weeks does not affect the expression of Na(+)/K(+) pump isoforms. Resting phosphorylation status of the Na...

Effects of 12-wk eccentric calf muscle training on muscle-tendon glucose uptake and SEMG in patients with chronic Achilles tendon pain

DEFF Research Database (Denmark)

Masood, Tahir; Kalliokoski, Kari; Magnusson, S Peter

2014-01-01

High-load eccentric exercises have been a key component in the conservative management of chronic Achilles tendinopathy. This study investigated the effects of a 12-wk progressive, home-based eccentric rehabilitation program on ankle plantar flexors' glucose uptake (GU) and myoelectric activity......, while the asymptomatic leg displayed higher uptake for medial gastrocnemius and flexor hallucis longus (P tendon GU than the controls (P effect on the tendon GU. Concerning SEMG, at baseline, soleus showed more relative...... within- or between-group differences. Eccentric rehabilitation was effective in decreasing subjective severity of Achilles tendinopathy. It also resulted in redistribution of relative electrical activity, but not metabolic activity, within the triceps surae muscle....

Circulating MicroRNA Responses between 'High' and 'Low' Responders to a 16-Wk Diet and Exercise Weight Loss Intervention.

Science.gov (United States)

Parr, Evelyn B; Camera, Donny M; Burke, Louise M; Phillips, Stuart M; Coffey, Vernon G; Hawley, John A

2016-01-01

Interactions between diet, physical activity and genetic predisposition contribute to variable body mass changes observed in response to weight loss interventions. Circulating microRNAs (c-miRNAs) may act as 'biomarkers' that are associated with the rate of change in weight loss, and/or play a role in regulating the biological variation, in response to energy restriction. To quantify targeted c-miRNAs with putative roles in energy metabolism and exercise adaptations following a 16 wk diet and exercise intervention in individuals with large (high responders; HiRes) versus small (low responders; LoRes) losses in body mass. From 89 male and female overweight/obese participants who completed the intervention (energy restriction from diet, 250 kcal/d, and exercise, 250 kcal/d), subgroups of HiRes (>10% body mass loss, n = 22) and LoRes (exercise and diet intervention suggests a putative role for these 'biomarkers' in the prediction or detection of individual variability to weight loss interventions.

Low Frequency Quasi-periodic Oscillations in the High-eccentric LMXB Cir X-1: Extending the WK Correlation for Z Sources

Energy Technology Data Exchange (ETDEWEB)

Bu, Qingcui; Chen, Li [Department of Astronomy, Beijing Normal University, Beijing 100875 (China); Belloni, T. M. [INAF-Osservatorio Astronomico di Brera, Via E, Bianchi 46, I-23807 Merate (Italy); Qu, Jinlu, E-mail: buqc@mail.bnu.edu.cn, E-mail: tomaso.belloni@brera.inaf.it, E-mail: chenli@bnu.edu.cn, E-mail: qujl@ihep.ac.cn [Laboratory for Particle Astrophysics, CAS, Beijing 100049 (China)

2017-06-01

Using archival Rossi X-ray Timing Explorer ( RXTE ) data, we studied the low-frequency quasi-periodic oscillations (LFQPOs) in the neutron star low-mass X-ray binary (LMXB) Cir X-1 and examined their contribution to frequency–frequency correlations for Z sources. We also studied the orbital phase effects on the LFQPO properties and found them to be phase independent. Comparing LFQPO frequencies in different classes of LMXBs, we found that systems that show both Z and atoll states form a common track with atoll/BH sources in the so-called WK correlation, while persistent Z systems are offset by a factor of about two. We found that neither source luminosity nor mass accretion rate is related to the shift of persistent Z systems. We discuss the possibility of a misidentification of fundamental frequency for horizontal branch oscillations from persistent Z systems and interpreted the oscillations in terms of models based on relativistic precession.

Dietary vitamin D dose-response in healthy children 2 to 8 y of age: a 12-wk randomized controlled trial using fortified foods.

Science.gov (United States)

Brett, Neil R; Lavery, Paula; Agellon, Sherry; Vanstone, Catherine A; Maguire, Jonathon L; Rauch, Frank; Weiler, Hope A

2016-01-01

Vitamin D is fundamental for bone health. A high proportion of Canadian 2- to 8-y-olds do not meet the Estimated Average Requirement (EAR) of 400 IU/d. The objective was to determine whether vitamin D intakes consistent with the EAR or Recommended Dietary Allowance (RDA), through fortification of additional dairy products, would result in higher vitamin D status in young children. Participants aged 2-8 y (n = 77; Montreal, Canada) were randomly assigned to 1 of 3 dietary vitamin D targets (control; EAR: 400 IU/d; or RDA: 600 IU/d) for 12 wk (January to April 2014). Anthropometric measurements, demographic characteristics, dietary intakes, fasting serum parathyroid hormone, 25-hydroxyvitamin D [25(OH)D], and ionized calcium were compared by using mixed-model ANOVA. Participants' mean ± SD age was 5.1 ± 1.9 y; 54.5% were boys with body mass index z scores of 0.50 ± 0.85. Compliance was 85% overall. No differences were observed in baseline dietary vitamin D intakes or serum 25(OH)D. At 12 wk, the EAR and RDA groups had significantly higher vitamin D intakes [median (IQR): control, 227 (184-305) IU/d; EAR, 410 (363-516) IU/d; and RDA, 554 (493-653) IU/d; P D concentrations (control: 55.8 ± 12.3 nmol/L; EAR: 64.1 ± 10.0 nmol/L; and RDA: 63.7 ± 12.4 nmol/L; P D concentrations ≥50 nmol/L. Increasing the vitamin D intakes of young children through fortification of alternative dairy products results in significantly higher serum concentrations of 25(OH)D and a significantly greater proportion of children with serum 25(OH)D ≥50 nmol/L during periods of minimal ultraviolet B radiation exposure. This trial was registered at clinicaltrials.gov as NCT02097160 and had Health Canada Temporary Marketing Authorization Letters for both products (TM-13-0432 and TM-13-0433). © 2016 American Society for Nutrition.

Circulating MicroRNA Responses between ‘High’ and ‘Low’ Responders to a 16-Wk Diet and Exercise Weight Loss Intervention

Science.gov (United States)

Parr, Evelyn B.; Camera, Donny M.; Burke, Louise M.; Phillips, Stuart M.; Coffey, Vernon G.; Hawley, John A.

2016-01-01

Background Interactions between diet, physical activity and genetic predisposition contribute to variable body mass changes observed in response to weight loss interventions. Circulating microRNAs (c-miRNAs) may act as ‘biomarkers’ that are associated with the rate of change in weight loss, and/or play a role in regulating the biological variation, in response to energy restriction. Objective To quantify targeted c-miRNAs with putative roles in energy metabolism and exercise adaptations following a 16 wk diet and exercise intervention in individuals with large (high responders; HiRes) versus small (low responders; LoRes) losses in body mass. Methods From 89 male and female overweight/obese participants who completed the intervention (energy restriction from diet, 250 kcal/d, and exercise, 250 kcal/d), subgroups of HiRes (>10% body mass loss, n = 22) and LoRes (exercise and diet intervention suggests a putative role for these ‘biomarkers’ in the prediction or detection of individual variability to weight loss interventions. PMID:27101373

Growth of the pectoral girdle in a sample of juveniles from the kellis 2 cemetery, Dakhleh Oasis, Egypt.

Science.gov (United States)

Bleuze, Michele M; Wheeler, Sandra M; Williams, Lana J; Dupras, Tosha L

2016-09-10

This study investigates growth patterns in the scapula and clavicle in a cross-sectional juvenile skeletal sample ranging from 20 weeks gestation to 8.5 years of age from the Kellis 2 cemetery, Dakhleh Oasis, Egypt. The primary goal is to quantify growth patterns and growth velocities in the scapula and clavicle to better understand the development of the pectoral girdle. A series of low-order polynomial regression models was used to examine growth curves in clavicle diaphyseal length, scapular height, and scapular width. Incremental growth and relative percent increase were examined among successive age groups as a proxy measure of growth velocity. Scapular body proportions were assessed with the scapular index and compared across age groups using a Kruskal-Wallis test with post-hoc tests. A third-order polynomial best describes growth in clavicle diaphyseal length and scapular height, and a second-order polynomial best describes growth in scapular width. Growth velocity patterns are similar among clavicle diaphyseal length, scapular height, and scapular width particularly from birth until the end of early childhood. Clavicle diaphyseal length decelerates during middle childhood while scapular height and width accelerate during this time. With increasing age, the scapular body proportionately increases more in height than in width. The relatively narrow scapular body characteristic of adult scapulae is first evident during early childhood. Changes in scapular body shape during ontogeny may be a reflection of the greater alterations taking place in the integrated morphology of the pectoral girdle during the biomechanical shift from crawling to bipedalism. Am. J. Hum. Biol. 28:636-645, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

A low-fat vegan diet and a conventional diabetes diet in the treatment of type 2 diabetes: a randomized, controlled, 74-wk clinical trial.

Science.gov (United States)

Barnard, Neal D; Cohen, Joshua; Jenkins, David J A; Turner-McGrievy, Gabrielle; Gloede, Lise; Green, Amber; Ferdowsian, Hope

2009-05-01

Low-fat vegetarian and vegan diets are associated with weight loss, increased insulin sensitivity, and improved cardiovascular health. We compared the effects of a low-fat vegan diet and conventional diabetes diet recommendations on glycemia, weight, and plasma lipids. Free-living individuals with type 2 diabetes were randomly assigned to a low-fat vegan diet (n = 49) or a diet following 2003 American Diabetes Association guidelines (conventional, n = 50) for 74 wk. Glycated hemoglobin (Hb A(1c)) and plasma lipids were assessed at weeks 0, 11, 22, 35, 48, 61, and 74. Weight was measured at weeks 0, 22, and 74. Weight loss was significant within each diet group but not significantly different between groups (-4.4 kg in the vegan group and -3.0 kg in the conventional diet group, P = 0.25) and related significantly to Hb A(1c) changes (r = 0.50, P = 0.001). Hb A(1c) changes from baseline to 74 wk or last available values were -0.34 and -0.14 for vegan and conventional diets, respectively (P = 0.43). Hb A(1c) changes from baseline to last available value or last value before any medication adjustment were -0.40 and 0.01 for vegan and conventional diets, respectively (P = 0.03). In analyses before alterations in lipid-lowering medications, total cholesterol decreased by 20.4 and 6.8 mg/dL in the vegan and conventional diet groups, respectively (P = 0.01); LDL cholesterol decreased by 13.5 and 3.4 mg/dL in the vegan and conventional groups, respectively (P = 0.03). Both diets were associated with sustained reductions in weight and plasma lipid concentrations. In an analysis controlling for medication changes, a low-fat vegan diet appeared to improve glycemia and plasma lipids more than did conventional diabetes diet recommendations. Whether the observed differences provide clinical benefit for the macro- or microvascular complications of diabetes remains to be established. This trial was registered at clinicaltrials.gov as NCT00276939.

Kelly review

African Journals Online (AJOL)

USER

evidence that vitamin A has benefits for morbidity complexing with cellular retinol .... and direct an antibody-mediated There has been very little work on gut lymphoid ... innate pattern recognition receptors Toll-Like weekly for 8 weeks) given to ...

Effect of a 9-wk. after-school multiskills club on fundamental movement skill proficiency in 8- to 9-yr.-old children: an exploratory trial.

Science.gov (United States)

Foweather, Lawrence; McWhannell, Nicola; Henaghan, Jayne; Lees, Adrian; Stratton, Gareth; Batterham, Alan M

2008-06-01

This exploratory study examined the effects of a 9-wk. after-school multiskills club on fundamental movement skill proficiency in 8- to 9-yr.-old children. Two schools were randomly assigned to either a control (n = 15 children) or multiskill club (n = 19 children) condition. The multiskill club received 18 coaching sessions designed to improve fundamental movement skills. The control group followed normal routines. 7 skills were assessed using process-oriented measures with video analysis. Participation in the multiskill club yielded significant improvements in proficiency at posttest only in static balance, while potentially practically important improvements were observed in performance of the catch, throw, and kick skills. The after-school multiskill club offered a viable opportunity for movement skill acquisition, but any such programme would need to run for a longer duration to assess whether this type of activity could benefit all skills.

Effects of 12-wk eccentric calf muscle training on muscle-tendon glucose uptake and SEMG in patients with chronic Achilles tendon pain.

Science.gov (United States)

Masood, Tahir; Kalliokoski, Kari; Magnusson, S Peter; Bojsen-Møller, Jens; Finni, Taija

2014-07-15

High-load eccentric exercises have been a key component in the conservative management of chronic Achilles tendinopathy. This study investigated the effects of a 12-wk progressive, home-based eccentric rehabilitation program on ankle plantar flexors' glucose uptake (GU) and myoelectric activity and Achilles tendon GU. A longitudinal study design with control (n = 10) and patient (n = 10) groups was used. Surface electromyography (SEMG) from four ankle plantar flexors and GU from the same muscles and the Achilles tendon were measured during submaximal intermittent isometric plantar flexion task. The results indicated that the symptomatic leg was weaker (P eccentric rehabilitation. Additionally, the rehabilitation resulted in greater GU in both soleus (P tendon GU than the controls (P effect on the tendon GU. Concerning SEMG, at baseline, soleus showed more relative activity in the symptomatic leg compared with both the asymptomatic and control legs (P Eccentric rehabilitation was effective in decreasing subjective severity of Achilles tendinopathy. It also resulted in redistribution of relative electrical activity, but not metabolic activity, within the triceps surae muscle. Copyright © 2014 the American Physiological Society.

A low-fat vegan diet and a conventional diabetes diet in the treatment of type 2 diabetes: a randomized, controlled, 74-wk clinical trial1234

Science.gov (United States)

Barnard, Neal D; Cohen, Joshua; Jenkins, David JA; Turner-McGrievy, Gabrielle; Gloede, Lise; Green, Amber; Ferdowsian, Hope

2009-01-01

Background: Low-fat vegetarian and vegan diets are associated with weight loss, increased insulin sensitivity, and improved cardiovascular health. Objective: We compared the effects of a low-fat vegan diet and conventional diabetes diet recommendations on glycemia, weight, and plasma lipids. Design: Free-living individuals with type 2 diabetes were randomly assigned to a low-fat vegan diet (n = 49) or a diet following 2003 American Diabetes Association guidelines (conventional, n = 50) for 74 wk. Glycated hemoglobin (Hb A1c) and plasma lipids were assessed at weeks 0, 11, 22, 35, 48, 61, and 74. Weight was measured at weeks 0, 22, and 74. Results: Weight loss was significant within each diet group but not significantly different between groups (−4.4 kg in the vegan group and −3.0 kg in the conventional diet group, P = 0.25) and related significantly to Hb A1c changes (r = 0.50, P = 0.001). Hb A1c changes from baseline to 74 wk or last available values were −0.34 and −0.14 for vegan and conventional diets, respectively (P = 0.43). Hb A1c changes from baseline to last available value or last value before any medication adjustment were −0.40 and 0.01 for vegan and conventional diets, respectively (P = 0.03). In analyses before alterations in lipid-lowering medications, total cholesterol decreased by 20.4 and 6.8 mg/dL in the vegan and conventional diet groups, respectively (P = 0.01); LDL cholesterol decreased by 13.5 and 3.4 mg/dL in the vegan and conventional groups, respectively (P = 0.03). Conclusions: Both diets were associated with sustained reductions in weight and plasma lipid concentrations. In an analysis controlling for medication changes, a low-fat vegan diet appeared to improve glycemia and plasma lipids more than did conventional diabetes diet recommendations. Whether the observed differences provide clinical benefit for the macro- or microvascular complications of diabetes remains to be established. This trial was registered at clinicaltrials

Does Mobile Care ('mCare') Improve Quality of Life and Treatment Satisfaction Among Service Members Rehabilitating in the Community? Results from a 36-Wk, Randomized Controlled Trial.

Science.gov (United States)

Little, Jeanette R; Pavliscsak, Holly H; Cooper, Mabel R; Goldstein, Lois A; Fonda, Stephanie J

2018-03-01

Research has shown that mobile phones can help with management of numerous health problems. As an adjunct to care management provided to injured service members rehabilitating in their communities, particularly those with mild traumatic brain injury (mTBI), post-traumatic stress (PTS), and/or behavioral health problems, the Army developed a mobile phone application called "mCare." This study examined whether service members who received mCare had higher well-being, were more satisfied with their care, and viewed mCare as a valuable part of their care management as compared with their counterparts who received standard care management alone, and whether those with mTBI, PTS, and/or behavioral health problems benefited differently from mCare. In-processing service members at four community-based warrior transition units were recruited for participation in a 36-wk, randomized, controlled trial and allocated to receive standard care management plus mCare (n = 95) or standard care management alone (n = 87). Participants in the mCare group received daily questionnaires, tips, and appointment reminders. All participants were asked to complete the General Well-being Schedule (GWS) at baseline, 12, 24, and 36 wk, and the Case Management Quality Questionnaire (CMQQ) at 12, 24, and 36 wk. All participants and care managers were approached to complete interviews about the usability/likeability of mCare or standard care management. The analyses tested for group differences in completion of the intervention, graphed means for the GWS and CMQQ by group/subgroup, and statistically compared the longitudinal trends in these outcomes using mixed models in which group, time, and group*time were included as regression variables. The analyses also tallied interview responses and identified thematic quotes. The study protocol was reviewed and approved by the Walter Reed National Military Medical Center's Institutional Review Board. Estimated rate of change in GWS scores was -2

PENGARUH KOMUNIKASI PEMASARAN MELALUI WORD OF MOUTH TERHADAP KEPUTUSAN NASABAH DALAM MENGAMBIL KREDIT PADA AL-GIFFARI FINANCE

OpenAIRE

GIFFARI, ABIZAR

2016-01-01

2015 Penelitian ini bertujuan untuk menganalisis pengaruh komunikasi pemasaran melalui word of mouth terhadap keputusan nasabah dalam mengambil kredit pada Al-Giffari Finance. Penelitian ini menggunakan sampel sebanyak 70 Responden yang merupakan sebagian dari populasi penelitian karena menggunakan teknik sampling Slovin. Metode pengumpulan data adalah dengan menyebarkan kuisioner yang kemudian diolah dengan menggunakan analisis regeresi berganda. Uji yang digunakan untuk me...

Pursuing a constructivist approach to mentoring in the higher ...

African Journals Online (AJOL)

In this article we argue that Kelly's construct psychology (Kelly 1955; 1966/2003) provides a useful framework for mentoring in the Higher Education sector in South Africa. Kelly's notion of constructive alternativism prompts practitioners to adopt a questioning attitude to life in HE; newly appointed academic staff members ...

78 FR 70027 - Senior Executive Service; Performance Review Board

Science.gov (United States)

2013-11-22

..., WILLIAM N. BURROWS, CHARLES W. BUTTRESS, LARRY D. CADIEUX, GENA E. CALBOS, PHILIP T. CALLAHAN, SAMUEL N..., LARRY N. BELL, MELODY C. BESTANI, ROBERT M. BIENIAWSKI, ANDREW J. BIERBOWER, WILLIAM J. BINKLEY, JOHN S..., STAN M. KEARNEY, JAMES H. KELLY, HENRY C. KELLY, JOHN E. KELLY, LARRY C. KENCHINGTON, HENRY S. KENDELL...

Pengaruh Kualitas Pelayanan, Kebijakan Harga terhadap Kepuasan dan Loyalitas Pelanggan pada Jasa Lapangan Internasional Futsal Pekanbaru

OpenAIRE

Wijayanto, Gatot; Sukpa, Wiwik Dwi

2015-01-01

This study aims to determine how the variables influence service quality, pricing policy towards customer satisfaction and loyalty simultaneously or partially on international futsal field services pekanbaru. This study uses the technique of accidental sampling method sampling conducted by coincidence. To determine the number of samples using Slovin formula, and obtained a sample of 96 people from a total population of 2268 people. This study uses primary data, where the data obtained through...

The Influence of Spiritual Intelligence,Leadership, and Organizational Culture on Organizational Citizenship Behavior: a Study to Islamic Bank in Makassar City

OpenAIRE

HM, Muhdar; Rahma, St

2015-01-01

The aims of this study are to find out and to analys: (1) the influence of spiritual intelligence on organizational  citizenship  behavior; (2) the influence of leadership on organizational  citizenship  behavior; (3) the influence of organizationan culture on organizational  citizenship  behaviorThe population included all employees of Islamic Bank in Makassar City. There were 178 samples determined by using Slovin formula.  The samples were selected in two...

Kinerja Balai Penyuluhan Pertanian (BPP) dan Dampaknya pada Perilaku Petani Padi di Sulawesi Selatan

OpenAIRE

Jamil, Muh Hatta; Jahi, Amri; Gani, Darwis S; Sarma, Ma'mun; Purnaba, I Gusti Putu

2012-01-01

This research was aimed to know factors related to the action programs as a representation of BPP performance and relationship between factors that potentially increase BPP performance and their impacts to the behavioral changes of ricefield farmers in South Sulawesi. Population of this research were all BPP located in 15 districts (regencies) in South Sulawesi (176 sub-districts/150 BPP). Determination of samples used Slovin method, number of samples was 109 BPP located within 109 sub-distri...

Pengaruh Hygiene Factors Dan Motivating Factors Terhadap Kepuasan Kerja Dan Dampaknya Terhadap Organizational Citizenship Behavior (Ocb)

OpenAIRE

Feizal, Raden

2015-01-01

OCB behaviors can be implemented when employees get job satisfaction while toget job satisfaction, the employee needs to be fulfilled both hygienes or motivating. The aimof research want to know the fulfillment of the needs of employees can directly influence theOCB without going through job satisfaction. A population of 184 people with a samplingtechnique using simple random technique, the sample in this research Informa store staff levelemployees with the formula Slovin MAG, so that found a...

Analisis Permintaan Produk Nutrisi Shake Mix dari Herbalife di Kota Pekanbaru

OpenAIRE

Ekwarso, Hendro; Silitonga, William

2015-01-01

This research was conducted to determine the factors that influence the demand of nutrition product Shake Mix from Herbalife among reproductive age consumers in Pekanbaru city. The data used in this research is primary and secondary data. Using descriptive data analysis methods. The population in this research is peoples on productive age who consume Shake Mix sampled 100 respondents using the Slovin formula. The result of this research showed that the factors that influence the demand of Sha...

Pengaruh Pengalaman dan Pelatihan Auditor terhadap Struktur Pengetahuan Tentang Kekeliruan Auditor

OpenAIRE

Sri Haryanti, Caecilia

2013-01-01

The purpose of this study was to analyze the influence of auditor experience on knowledge of the error that occurred and analyze training on knowledge about the error that occurred. The study sample comprised 60 auditors covering large auditors, smalla uditors and students who have taken courses auditing. Size of sample size was determined using the formula Slovin, sampling techniques using simple random sampling. Multiple regression analysis is used to examine the effect of experience and t...

Pengaruh Disiplin dan Lingkungan Kerja terhadap Kinerja Karyawan Pabrik pada PT. Inti Karya Plasma Perkasa Tapung

OpenAIRE

Kholil, Muhammad Abdul

2014-01-01

This study was conducted at Factory PT. Inti Karya Plasma Perkasa Tapung the aim to determine the effect of variables discipline on the performance of the employees, work environment on employees performance and both variables discipline and work environme simultaneously affect employee the performance factory at PT.Inti Karya Plasma Perkasa Tapung. The technique used in this study is the technique Slovin (Umar, 2008: 82) to obtain a sample amounted to 107 employees of population 139 employee...

Pengaruh Intensi Turnover Dan Ketidakhadiran Terhadap Kinerja Pegawai Dinas Pendidikan DKI Jakarta

OpenAIRE

Fitri, Mutiara Annisa

2017-01-01

The research was conducted to teachers education office of DKI Jakarta. By using  a survey method with  path analysis applied in testing hypothesis the number 52 employee as sample was selected by using Slovin formula. Based on the results of data analysis in this research it is concluded: (1) the turnover intention have negative direct effect to job performance; (2) the absenteeism have negative direct effect to job performance; (3) the turnover intention have positif direct effect...

Pengaruh Kepemimpinan Situasional terhadap Semangat Kerja Perawat Rumah Sakit Santa Maria Pekanbaru

OpenAIRE

Sutrisna, Endang; Anggrenni, Dian Prapty

2015-01-01

This research aims to find the implications of leadership on keep spirit of nurses in Santa Maria Hospital Pekanbaru. Leadership as an independent variable (X) consist of leadership telling, selling, participating, and delegating. And keep spirit as the dependent variable (Y) cosist pf salary, incentive and allowance and improvement of welfare.The research used sample of the nurses in Santa Maria Pekanbaru. The number of this sample is 67 persons with slovin. This research is also used Strati...

78 FR 1253 - Notice of Determinations Regarding Eligibility to Apply for Worker Adjustment Assistance

Science.gov (United States)

2013-01-08

..., 2011. Department, Kelly Services and Contemporary Personnel. 82,126 Covidien Plc, Cash Mansfield, MA......... November 1, 2011. Application and Invoice Adjustments Department, Kelly Services. The following...

PERAN STRES KERJA DAN KEPUASAN KERJA UNTUK MENGURANGI TURNOVER INTENTION

Directory of Open Access Journals (Sweden)

Syarifah Nazenin

2014-09-01

Full Text Available Tujuan penelitian ini untuk menguji pengaruh variabel stres kerja dan kepuasan kerja pada turnover intention karyawan tetap bagian produksi. Sampel penelitian ini adalah 86 responden, menggunakan metode Slovin dengan teknik probability sampling dengan jenis proportionate random sampling. Berdasarkan hasil penelitian, menunjukkan bahwa stres kerja berpengaruh positif signifikan pada turnover intention. Kemudian, kepuasan kerja berpengaruh negatif signifikan. Penelitian ini menyimpulkan, bahwa stres kerja berpengaruh positif dan signifikan pada turnover intention karyawan dan kepuasan kerja berpengaruh negatif dan signifikan terhadap turnover intention karyawan. Implikasi manajerial yang bisa dilakukan adalah dengan pengurangan tingkat stres karyawan dan membuat program untuk tujuan menekan turnover intention, seperti kesempatan promosi dan meningkatkan reward karyawan. The purpose of this study conducted to examine the effect of work stress and job satisfaction on turnover intention of employee in production department. The sample was 86 respondent, using Slovin method with proportionate random sampling technique. The result showed that job stress has a positive effect on turnover intention while job satisfaction has a negative effect on turnover intention. This study conclude that job stress has positive and significant impact on employee turnover intention and job satisfaction significantly and negatively related to turnover intention of employees. Therefore, it is recommended to managerial level people to reduce stress levels in employees and to create a program for pressing turnover intention, such as promotional opportunities and improve employee rewards.

PENGARUH WORK LIFE BALANCE DAN KETERIKATAN PEGAWAI TERHADAP KINERJA PEGAWAI FAKULTAS ILMU SOSIAL DAN ILMU POLITIK UNIVERSITAS INDONESIA

OpenAIRE

Sarikit, Maya

2017-01-01

The objective of the research is to obtain information about the influence of work life balance and employee engagementon employees job performance onFaculty of Social and Political Sciences of the University of Indonesia .The research was conducted to all of employees onFaculty of Social and Political Sciences of the University of Indonesia by using a survey method with path analysis applied in testing hypothesis. The number 67 employees as sample was selected by using Slovin formula. The re...

The Red Dress: Getting to the Heart of Women's Health

Science.gov (United States)

... Calvin Klein (second from left), Elaine Stritch for Charles Nolan (center left), Kelly Rowland for House of ... Kelly Rowland. This year, leading celebrities and designers will debut "Celebrated Women 2007," the fifth collection of ...

Otshen svojevremennoje samoubiistvo / Vladimir Abarinov

Index Scriptorium Estoniae

Abarinov, Vladimir

2003-01-01

Ilmunud ka: Den za Dnjom 25. juuli lk. 11. Suurbritannia kaitseministeeriumi relvaeksperdi David Kelly surma asjaolusid uurib lord Hutton. Peaminister Tony Blair'i ja kaitseminister Geoff Hoom'i osast Kelly nime esiletoomisel Iraagi luureskandaalis

Plummer-Vinson Syndrome with Improvement After Iron Repletion

African Journals Online (AJOL)

10.4314/aas.v13i2.11. Introduction. Plummer-Vinson syndrome (synonyms: Paterson-. Kelly Syndrome, Paterson-Brown Kelly syndrome,. Sideropenic dysphagia), is defined by the classic triad of dysphagia, iron deficiency anemia and esophageal.

Analisis Faktor-Faktor Yang Mempengaruhi Kesejahteraan Petani Padi di Kecamatan Babalan Kabupaten Langkat

OpenAIRE

Fadhillah, Warid

2016-01-01

The purpose of this study is to analyze the factors that affect the welfare of rice farmers in the district Babalan Langkat using primary data for 100 respondents was determined by the formula Slovin, represent the entire population of rice farmers in the district Babalan Langkat. The sampling technique using random sampling method, which means selecting a random sample by giving a same chance to all members of the population to be a member of the sample. The method used in this research i...

76 FR 4726 - General Motors Company Formerly Known as General Motors Corporation Technical Center Including On...

Science.gov (United States)

2011-01-26

... Technology Associates Limited, G-Tech Professional Staffing, Inc., Jefferson Wells, Kelly Services, Inc... Enterprise Services, Engineering Labs, Inc., Global Technology Associates Limited, G-Tech Professional...., Global Technology Associates Limited, G-Tech Professional Staffing, Inc., Jefferson Wells, Kelly Services...

76 FR 14691 - Delphi Steering, Including On-Site Leased Workers From Acro Service Corporation, Aerotek, Inc...

Science.gov (United States)

2011-03-17

... Contract Services, Integrated Partners Group LLC, Kelly Services, Manpower, Inc., Rapid Global Business Solutions, Inc., TAC Worldwide, Trialon Corp., Trison Business Solutions, Wright K. Technologies, Interim... Services, Integrated Partners Group LLC, Kelly Services, Manpower, Inc., Rapid Global Business Solutions...

76 FR 32227 - DST Systems, Inc., Including On-Site Leased Workers From Comsys Information Technology Services...

Science.gov (United States)

2011-06-03

..., Inc., Including On-Site Leased Workers From Comsys Information Technology Services, Megaforce, and Kelly Services Kansas City, MO; DST Technologies, a Wholly Owned Subsidiary of DST Systems, Inc., Boston... Information Technology Services, Megaforce, and Kelly Services, Kansas City, Missouri (subject firm). The...

Pärnu jätkab Europan-projektiga / Karin Paulus

Index Scriptorium Estoniae

Paulus, Karin, 1975-

2005-01-01

2003. aastal toimunud arhitektuurikonkursi Europan 7 võidutöö "Teine loodus" (arhitektid Oana-Maria Bogdan, Kelly Shannon jt.) põhjal valminud eskiisprojektist Pärnus mere ning Tammsaare puiestee vahelisele krundile. Triin Ojari selgitab võistluse olemust. Arhitekt Kelly Shannon külastas Pärnut

Spectroscopic Data for an Astronomy Data Base

Science.gov (United States)

Parkinson, W. H.; Smith, Peter L.

1997-01-01

When we began this work, very few of the atomic and molecular data used by astronomers in the analysis of astronomical spectra were available in on-line searchable databases. Our principal goal was to: make the most useful of the atomic data files of R.L. Kurucuz (1995a,b) available on the WWW; and also to make the atomic data of R.L. Kelly for ultraviolet lines (i.e., essentially the same as the data in Kelly (1979) and Kelly (1987)) similarly available. In addition, we proposed to improve access to parameters for simple molecules of interest to astronomers.

75 FR 3250 - Glaxosmithkline, Including On-Site Temporary and Leased Workers From Kelly Services, Kelly...

Science.gov (United States)

2010-01-20

... subject firm. The workers are engaged in the production of penicillin-based antibiotics for humans and animals. The company reports that on-site leased workers from Dream Clean, Inc. were employed on-site at...

76 FR 45600 - Columbia National Wildlife Refuge, Adams and Grant Counties, WA; Draft Comprehensive Conservation...

Science.gov (United States)

2011-07-29

... message. Fax: Attn: Kelly Chase, (509) 546-8303. U.S. Mail: Kelly Chase, Refuge Manager, Columbia National... The National Wildlife Refuge System Administration Act of 1966 (16 U.S.C. 668dd-668ee), (Refuge... National Wildlife Refuge System, consistent with sound principles of fish and wildlife management...

DAMPAK IMPLEMENTASI UNDANG-UNDANG AKUNTAN PUBLIK TERHADAP MINAT MENJADI AKUNTAN PUBLIK STUDI KASUS MAHASISWA AKUNTANSI UNIVERSITAS NEGERI SEMARANG

Directory of Open Access Journals (Sweden)

Sukardi Ikhsan

2014-07-01

Full Text Available Tujuan dari penelitian ini adalah untuk menemukan bukti empiris pengaruh implementasi UU Akuntan Publik terhadap minat menjadi akuntan publik. Penelitian dilakukan pada mahasiswa Akuntansi Universitas Negeri Semarang. Sampel dihitung dengan menggunakan rumus Slovin. Sebanyak 150 kuesionair disebarkan kepada responden secara acak (random. Dan terakhir diperoleh kuesionair yang dapat digunakan untuk diteliti sebanyak 70 buah atau dapat dikatakan respon rate sebesar 47%. Selanjutnya data primer yang telah dikumpulkan diolah dan dianalisis menggunakan analisis statistik deskriptif. Sedangkan hipotesis diuji dengan regresi. Hasil penelitian menunjukkan bukti empiris bahwa implementasi UU Akuntan Publik berpengaruh positif terhadap minat menjadi akuntan publik. Namun demikian pengaruh tersebut sangat kecil, hal tersebut ditengarahi oleh pemahaman responden terhadap UU Akuntan Publik yang masih minim. The purpose of this study was to find empirical evidence of the effect of implementation of the Law on Public Accountants into interests become public accounting. The study was conducted on Accounting students of Semarang State University. Sample size was calculated using the formula Slovin. Furthermore, as many as 150 questionnaire distributed to respondents in random order (random. Questionnaire obtained can be used to study many as 70 pieces or may be a response rate of 47%. Furthermore, primary data was collected were processed and analyzed using statistical analysis descriptive. While the hypothesis was tested by regression. The results showed empirical evidence that implementation of the Public Accounting Act positive influence into interests become public accounting. However, the effect is very small, it is because of the understanding of the respondents to the Public Accounting Act was minimal.

75 FR 69061 - Senior Executive Service; Performance Review Board

Science.gov (United States)

2010-11-10

..., Linda C Burrows, Charles W Buttress, Larry D Buzzard, Christine M Cadieux, Gena E Callahan, Samuel N... Bekkedahl, Larry N Bell, Melody C Berkowitz, Barry E Bieniawski, Andrew J Bishop, Clarence T Bishop, Tracey..., Douglas E Kane, Michael C Kaplan, Stan M Kearney, James H Kelly, Henry C Kelly, Larry C Kenchington, Henry...

77 FR 64967 - Senior Executive Service; Performance Review Board

Science.gov (United States)

2012-10-24

... BROWN, STEPHANIE H BRYAN, WILLIAM N BURROWS, CHARLES W BUTTRESS, LARRY D CADIEUX, GENA E CALBOS, PHILIP..., CAROL J BEAMON, JOSEPH A BEARD, JEANNE M BEARD, SUSAN F BEAUSOLEIL, GEOFFREY L BEKKEDAHL, LARRY N BELL..., HENRY C KELLY, JOHN E KELLY, LARRY C KENCHINGTON, HENRY S KENDELL, JAMES M KETCHAM, TIMOTHY E KHAN...

PENGARUH PEMAHAMAN, SANKSI PERPAJAKAN, TINGKAT KEPERCAYAAN PADA PEMERINTAH DAN HUKUM, SERTA NASIONALISME TERHADAP 22 KEPATUHAN WAJIB PAJAK DALAM MEMBAYAR PBB-P2 (Studi Pada Wajib Pajak PBB-P2 di Kota Banjar

Directory of Open Access Journals (Sweden)

Apriani Purnamasari

2018-03-01

Full Text Available The main purpose of this research is to examine the effect of perceived tax understanding, tax penalties, trust in government and law, and nationalism towards taxpayer compliance in paying property tax. Using Slovin formula, 100 respondents were selected as representative sample from the tax payers in Banjar, Indonesia. Data were collected using closed questionnaire and analyzed by multiple linear regression. The results showed that the understanding of tax regulation, tax penalties, and nationalism had significantly positive effect. However, trust in goverment and the law did not significantly affect taxpayer compliance in paying property tax.

Two Classification Methods for Grouping Common Environmental Sounds in Terms of Perceived Pleasantness

Science.gov (United States)

2016-02-01

NUMBER OF PAGES 24 19a. NAME OF RESPONSIBLE PERSON Kelly Dickerson a. REPORT Unclassified b. ABSTRACT Unclassified c . THIS...ARL-TR-7960 ● FEB 2016 US Army Research Laboratory Two Classification Methods for Grouping Common Environmental Sounds in Terms...of Perceived Pleasantness by Kelly Dickerson, Brandon S Perelman, Laura Sherry, and Jeremy R Gaston Approved for public

Convergence And Exploitation: Transnational Organized Crime, Terrorism And The Threat To America

Science.gov (United States)

2015-05-18

and avenues of approach that could enable a terrorist attack on U.S. soil . Background Since the fall of the Soviet Union, global stability as...2014. Revolutionary Armed Forces of Colombia (FARC). Communist terrorist organization established to overthrow the government of... Colombia . 4 John Kelly, “Testimony,” Senate, Posture Statement of General John F. Kelly, United States

Research from the NASA Twins Study and Omics in Support of Mars Missions

Science.gov (United States)

Kundrot, C.; Shelhamer, M.; Scott, G.

2015-01-01

The NASA Twins Study, NASA's first foray into integrated omic studies in humans, illustrates how an integrated omics approach can be brought to bear on the challenges to human health and performance on a Mars mission. The NASA Twins Study involves US Astronaut Scott Kelly and his identical twin brother, Mark Kelly, a retired US Astronaut. No other opportunity to study a twin pair for a prolonged period with one subject in space and one on the ground is available for the foreseeable future. A team of 10 principal investigators are conducting the Twins Study, examining a very broad range of biological functions including the genome, epigenome, transcriptome, proteome, metabolome, gut microbiome, immunological response to vaccinations, indicators of atherosclerosis, physiological fluid shifts, and cognition. A novel aspect of the study is the integrated study of molecular, physiological, cognitive, and microbiological properties. Major sample and data collection from both subjects for this study began approximately six months before Scott Kelly's one year mission on the ISS, continue while Scott Kelly is in flight and will conclude approximately six months after his return to Earth. Mark Kelly will remain on Earth during this study, in a lifestyle unconstrained by this study, thereby providing a measure of normal variation in the properties being studied. An overview of initial results and the future plans will be described as well as the technological and ethical issues raised for spaceflight studies involving omics.

ORGANIZATIONAL CITIZENSHIP BEHAVIOR DAN PEMBERDAYAAN TERHADAP KOMITMEN ORGANISASI SERTA DAMPAKNYA TERHADAP KINERJA KARYAWAN

Directory of Open Access Journals (Sweden)

Idayanti Nursyamsi

2017-03-01

Full Text Available The success of banking institutions in providing excellent service to the customer was inseparable from theperformance of employees. This research aimed to study the influence of organizational citizenship behaviorand empowerment to organizational commitment and the influence to employee performance. Primary datawas taken by using questionnaires given to 128 employees by using Slovin formula. Path analysis model wasused to test the research hypothesis. The results showed that the level of employee performance positivelyinfluenced by organizational citizenship behavior, and employee empowerment and also comitment organizationalhad significant influence to employee performance. Improving the performance of employees was achallenge for banking institutions because employees were the important assets for the company.

Program Visualization

Science.gov (United States)

1983-02-22

Scientific Computing Symposiumn an Han-Machine C om unication (1965) 57-71. 1353 Sutherland , l.3., SUICUPADs a man-machine graphical comunica- tie. systems...Institute and was held at the university’s Idylwild Campus. July 1982 Craig Fields and Clint Kelly of DARPA visited CCA on July 6. Christopher Herot and...on December 9. We gave him an extended PV slide presentation and a demonstration of the system. Clint Kelly of DARPA visited on January 13, and he

Produkce vybraných metabolitů karotenogenními kvasinkami kultivovanými na potravinářských odpadech

OpenAIRE

Turková, Lucie

2015-01-01

U použitých kmenů kvasinek (Cystofilobasidium capitatum, Rhodotorula glutinis, Sporobolomyces shibatanus a Sporobolomyces roseus) byla sledována produkce vybraných metabolitů - zejména karotenoidů, dále pak i ergosterolu a koenzymu Q. Kvasinky byly kultivovány na odpadních substrátech z vinařství - výliscích (slupkách) a třapinách. Odpadní substráty byly podrobeny analýze obsahu sacharidů, tuků, tříslovin, polyfenolů a dalších látek. Kultivace probíhaly též na chemicky a enzymově hydrolyzovan...

The Wk structure of the Zk(3/2) models

International Nuclear Information System (INIS)

Mathieu, P

2009-01-01

Generalized Z k (r/2) parafermionic theories-characterized by the dimension (r/2)(1 - 1/k) of the basic parafermionic field-provide potentially interesting quantum-Hall trial wavefunctions. Such wavefunctions reveal a W k structure. This suggests the equivalence of (a subclass of) the Z k (r/2) models and the W k (k+1,k+r) ones. This is demonstrated here for r = 3 (the Gaffnian series). The agreement of the parafermionic and the W spectra relies on the prior determination of the field identifications in the parafermionic case.

Response to: Brief Comments on “Siddhis and Psi Research: An Interdisciplinary Analysis”

Directory of Open Access Journals (Sweden)

SONALI BHATT MARWAHA

2017-06-01

Full Text Available In his brief comments on “Siddhis and Psi Research: An Interdisciplinary Analysis,” Ed Kelly expresses disappointment that the paper does not mirror his worldview, which includes questioning the reality of psi—especially precognition, accepting post-mortem survival and observational evidence for macro-PK including levitation. In this brief response to Kelly, I provide arguments in support of informational psi, particularly precognition, and in favor of a physicalist, signal-based approach to psi, with brief points against the validity of micro-PK (mind-over-matter and post-mortem survival.

THE INFLUENCE OF SPIRITUAL INTELLIGENCE,LEADERSHIP, AND ORGANIZATIONAL CULTURE ON ORGANIZATIONAL CITIZENSHIP BEHAVIOR: A STUDY TO ISLAMIC BANK IN MAKASSAR CITY

Directory of Open Access Journals (Sweden)

Muhdar. HM

2015-06-01

Full Text Available The aims of this study are to find out and to analys: (1 the influence of spiritual intelligence on organizational citizenship behavior; (2 the influence of leadership on organizational citizenship behavior; (3 the influence of organizationan culture on organizational citizenship behaviorThe population included all employees of Islamic Bank in Makassar City. There were 178 samples determined by using Slovin formula. The samples were selected in two stages: proportional and purposive sampling. The data were analyzed by using path analysis with the AMOS 21 program. The results show that: spiritual intelligence has a positive and significant influence on organizational citizenship behavior; leadership has a positive and significant influence on organizational citizenship behavior; organizational culture has a positive and significant influence on organizational citizenship behavior.

Changes in stress hormones and metabolism during a 105-day simulated Mars mission.

Science.gov (United States)

Strollo, Felice; Vassilieva, Galina; Ruscica, Massimiliano; Masini, Mariangela; Santucci, Daniela; Borgia, Luisa; Magni, Paolo; Celotti, Fabio; Nikiporuc, Igor

2014-08-01

The Mars-105 project was aimed at simulating crew's activities, workload, and communication during a mission to Mars, evaluating the homeostatic adaptations to prolonged confinement and cohabitation. Fasting plasma glucose (FPG) and insulin, C-peptide, leptin, cortisol, and NGF and BDNF plasma levels were monitored in six healthy nonsmoking male subjects taking part in a 105-d Mars mission simulation. Samples were collected from each subject before (0 wk), during (2.5 wk; 5 wk; 10 wk; 15 wk), and after confinement (+1 wk). Confinement resulted in impaired glucometabolic parameters, since FPG increased during the first 5 wk (baseline: 85.2 ± 10.8 mg · dl⁻¹; 2.5 wk: 98.4 ± 4.7 mg · dl⁻¹; 5 wk: 92.5 ± 6.0 mg · dl⁻¹) and insulin dropped at 2.5 wk (baseline: 14.4 ± 4.8 mU · L⁻¹; 2.5 wk: 7.7 ± 2.1 mU · L⁻¹), subsequently returning to baseline values. HOMA-IR paralleled plasma insulin, dropping to 1.8 ± 0.5 at 2.5 wk (baseline: 3.0 ± 1.2). At all time-points tested, plasma leptin levels were decreased (baseline: 4.4 ± 3.3 ng · dl⁻¹; 2.5 wk: 1.6 ± 1.2 ng · dl⁻¹; 5 wk: 1.3 ± 0.8 ng · dl⁻¹; 10 wk: 1.5 ± 1.1 ng · dl⁻¹; 15 wk:1.7 ± 0.8 ng · dl⁻¹), whereas cortisol levels were increased (baseline: 10.8 ± 4.9 ng · dl⁻¹; 2.5 wk: 16.8 ± 3.5 ng · dl⁻¹; 5 wk: 18.1 ± 7.6 ng · dl⁻¹; 10 wk: 18.1 ± 8.3 ng · dl⁻¹; 15 wk:14.2 ± 4.4 ng · dl⁻¹), resulting in a negative correlation between these hormones. BDNF levels increased only at 5 and 10 wk (baseline: 67.1 ± 36.0 pg · ml⁻¹; 5 wk: 164 ± 54 pg · ml⁻¹; and 10 wk: 110.2 ± 28.9 pg · ml⁻¹). The data obtained with the Mars-105 experiment suggest that environmental stress has a strong impact upon metabolic and stress response, indicating the need for further studies and the implementation of specific countermeasures.

Deicing System Protects General Aviation Aircraft

Science.gov (United States)

2007-01-01

Kelly Aerospace Thermal Systems LLC worked with researchers at Glenn Research Center on deicing technology with assistance from the Small Business Innovation Research (SBIR) program. Kelly Aerospace acquired Northcoast Technologies Ltd., a firm that had conducted work on a graphite foil heating element under a NASA SBIR contract and developed a lightweight, easy-to-install, reliable wing and tail deicing system. Kelly Aerospace engineers combined their experiences with those of the Northcoast engineers, leading to the certification and integration of a thermoelectric deicing system called Thermawing, a DC-powered air conditioner for single-engine aircraft called Thermacool, and high-output alternators to run them both. Thermawing, a reliable anti-icing and deicing system, allows pilots to safely fly through ice encounters and provides pilots of single-engine aircraft the heated wing technology usually reserved for larger, jet-powered craft. Thermacool, an innovative electric air conditioning system, uses a new compressor whose rotary pump design runs off an energy-efficient, brushless DC motor and allows pilots to use the air conditioner before the engine even starts

Artemether as adjuvant therapy to praziquantel in murine Egyptian schistosomiasis mansoni.

Science.gov (United States)

Mahmoud, M R; Botros, S S

2005-02-01

We investigated the activity of artemether (ART) against different developmental stages of schistosomes alone and in addition to praziquantel (PZQ). ART was administered orally (400 mg/kg) 4 and 6 wk postinfection (PI), 4 and 5 wk PI, or 4 or 6 wk PI alone and in addition to oral PZQ (500 x 2 mg/kg) 6 wk PI. Mice were killed in parallel to infected untreated controls 8 wk PI. Parasitological parameters and histological changes in the liver were studied. ART given 4 and 6 wk PI reduced worm burdens by 59 and 55% and tissue egg load by 96 and 90%, respectively. Moreover, eggs in different developmental stages were not found. The reduction in worm and egg burden (63 and 58%, and 96 and 99%, respectively) in mice treated with ART 4 and 5 wk or 4 and 6 wk PI was comparable with that in ART-treated mice at 4 or 6 wk PI. Compared with PZQ alone, combined treatment of PZQ and ART (4 and 5 wk or 4 and 6 wk PI) did not enhance worm eradication, but there was a complete absence of parasite eggs. Livers revealed no granulomata when ART was given 4 and 5 wk or 4 and 6 wk PI, with minimal central necrosis in those treated 4 and 6 wk PI. In conclusion, combined treatment of ART (4 and 6 wk PI) and PZQ resulted in >90% worm eradication and amelioration of Schistosoma mansoni eggs from the tissues, with minor histological changes in the liver.

Forecasting of heat capacity of molecular inorganic liquids

International Nuclear Information System (INIS)

Sladkov, I.B.; Neganov, O.S.

1992-01-01

On the basis of analysis of experimental material on heat capacity of liquids, covering 350 molecular inorganic compounds, atomic parts of heat capacity for 58 elements of the Periodic system were obtained. Data on the accuracy of heat capacity calculation by the Neumann-Kopp rule using the recommended atomic parts C p are presented. For the Kelli rule it is assertained that the factor of proportiomality between heat capacity and the number of atoms in compound molecule in the general case depends on the type of anion and compound coordination. The Neumann-Kopp-Kelli rules provide a satisfactory accuracy of prediction

PENGARUH TINGKAT PENDIDIKAN TERHADAP PRESTASI KERJA KARYAWAN MELALUI MOTIVASI KERJA SEBAGAI INTERVENING

Directory of Open Access Journals (Sweden)

Lis Tatin Hernidatiatin

2017-06-01

Full Text Available Abstract. This study is aimed to analyze the direct and indirect effect of educational level on employee performance through work motivation as an intervening variable at PT. Kereta Api (Persero Regional Operations (DAOP 3 Cirebon. The method used in this research is associative method and data collection technique used is the field research (observation, interview, questionnaire and literature study. To determine the size of the sample, the study used the Slovin formula while to analyse data the researchers performed validity, reliability and classical assumption test (normality, multicollinearity, heteroscedasticity and autocorrelation test, path analysis, t hypothesis testing. The results of path analysis showed that the level of education directly impacted to employee performance and indirectly to work motivation (an intervening variable and finally to employee performance. Due to the fact that the direct correlation coefficient is greater than the indirect correlation coefficient, it can be said that the true relationship is direct correlation. Keywords. Level of education; work motivation; job performance.   Abstrak. Penelitian ini bertujuan untuk menganalisis pengaruh langsung tingkat pendidikan terhadap prestasi kerja karyawan dan pengaruh tidak langsung tingkat pendidikan terhadap prestasi kerja karyawan melalui motivasi kerja sebagai variabel intervening pada PT. Kereta Api (Persero Daerah Operasi (DAOP 3 Cirebon. Metode yang akan digunakan dalam penelitian ini adalah metode Asosiatif. Tehnik pengumpulan data yang digunakan adalah Riset Lapangan (Observasi, Wawancara, Angket dan Riset Kepustakaan. Untuk menentukan ukuran sampel menggunakan rumus Slovin. Penelitian ini menggunakan metode analisis data yang terdiri dari Uji validitas, Uji reliabilitas, Uji Asumsi Klasik (Uji Normalitas, Uji Multikolonearitas, Uji Heteroskedastisitas, Uji Autokorelasi, Analisis Jalur, Uji  t Hipotesis. Hasil analisis jalur menunjukkan bahwa tingkat

Long-term effects of weight reduction on the severity of psoriasis in a cohort derived from a randomized trial

DEFF Research Database (Denmark)

Jensen, Peter; Christensen, Robin; Zachariae, Claus

2016-01-01

randomized phase with an LED for 8 wk and 8 wk of normal food intake combined with 2 LED products/d, followed by a 48-wk period of weight maintenance with the latter diet. After the randomization phase, the control group received the same 8 + 8-wk LED intervention, and all patients were then followed for 48...... who were allocated to a control group or a low-energy diet (LED) group. Here we followed the participants for an additional 48-wk period. In total, 56 patients with psoriasis [mean ± SD body mass index (in kg/m(2)): 34.4 ± 5.3] underwent a 64-wk weight-loss program consisting of an initial 16-wk...... wk while on the weight-loss maintenance diet. The main outcome was the Psoriasis Area and Severity Index (PASI), and secondary outcome was the Dermatology Life Quality Index (DLQI). RESULTS: For the present study, 56 patients were eligible, 38 agreed to participate, and 32 completed. After the 16-wk...

Effect of fenbendazole on three behavioral tests in male C57BL/6N mice.

Science.gov (United States)

Gadad, Bharathi S; Daher, João P L; Hutchinson, Eric K; Brayton, Cory F; Dawson, Ted M; Pletnikov, Mikhail V; Watson, Julie

2010-11-01

Pinworms are highly contagious parasites of laboratory rodents that often are treated with fenbendazole. To our knowledge, the effect of fenbendazole at therapeutic dosages on behavioral tests in mice has not been evaluated. Here we studied 6-wk-old male C57BL/6N mice. We compared the behavior of control mice (fed regular diet) with 3 groups of mice treated with dietary fenbendazole. Treatment groups were 4 wk of fenbendazole, 2 wk of fenbendazole followed by 2 wk of regular diet, and 2 wk of regular diet followed by 2 wk of fenbendazole. At the end of dietary treatment all groups were tested by open field for central, peripheral and vertical activity; elevated plus maze for anxiety; and rotarod for motor ability and then evaluated by clinical pathology and selected histopathology. Treated and control groups showed no differences in open field or elevated plus maze testing, histopathology, or clinical pathology. However mice treated for 4 wk with fenbendazole or 2 wk of fenbendazole followed by 2 wk regular diet stayed on the rotarod for shorter periods than did controls, and mice treated with 2 wk of regular diet followed by 2 wk fenbendazole showed a trend toward shorter rotarod times. In light of this study, we suggest that open field and elevated plus maze testing is unlikely to be affected by 4 wk fenbendazole treatment in male C57BL/6 mice; however, behavioral tests of motor ability such as rotarod tests may be affected during and for at least 2 wk after fenbendazole treatment.

Oral Metronomic Topotecan Sensitizes Crizotinib Antitumor Activity in ALKF1174L Drug-Resistant Neuroblastoma Preclinical Models

Directory of Open Access Journals (Sweden)

Libo Zhang

2017-08-01

Full Text Available BACKGROUND: Anaplastic lymphoma kinase (ALK inhibitor crizotinib has proven to be effective in the treatment of ALK-mutated neuroblastoma, but crizotinib resistance was commonly observed in patients. We aimed to overcome crizotinib resistance by combining with the MEK inhibitor trametinib or low-dose metronomic (LDM topotecan in preclinical neuroblastoma models. METHODS: We selected a panel of neuroblastoma cell lines carrying various ALK genetic aberrations to assess the therapeutic efficacy on cell proliferation in vitro. Downstream signals of ALK activation, including phosphorylation of ERK1/2, Akt as well as HIF-1α expression were evaluated under normoxic and hypoxic conditions. Tumor growth inhibition was further assessed in NOD/SCID xenograft mouse models. RESULTS: All NBL cell lines responded to crizotinib treatment but at variable ED50 levels, ranging from 0.25 to 5.58 μM. ALK-mutated cell lines SH-SY5Y, KELLY, LAN-5, and CHLA-20 are more sensitive than ALK wild-type cell lines. In addition, we demonstrated that under hypoxic conditions, all NBL cell lines showed marked decrease of ED50s when compared to normoxia except for KELLY cells. Taking into consideration the hypoxia sensitivity to crizotinib, combined treatment with crizotinib and LDM topotecan demonstrated a synergistic effect in ALKF1174L-mutated SH-SY5Y cells. In vivo, single-agent crizotinib showed limited antitumor activity in ALKF1174L-mutated SH-SY5Y and KELLY xenograft models; however, when combined with topotecan, significantly delayed tumor development was achieved in both SH-SY5Y and KELLY tumor models. CONCLUSIONS: Oral metronomic topotecan reversed crizotinib drug resistance in the ALKF1174L-mutated neuroblastoma preclinical model.

Kimono Fusion - ultratraditsioonilisest hüpermoodsaks / Kelly Kipper

Index Scriptorium Estoniae

Kipper, Kelly

2010-01-01

Näitus "Kimono Fusion - ultratraditsioonilisest hüpermoodsaks" Stockholmis Östasiatiska muuseumis 10. jaanuarini 2010. Eksponeeritakse kimonosid ja obisid (traditsioonilised kimonovööd) ning jaapani moekunstnike loomingut. Lähemalt Shin Tanaka, Shojono Tomo, duo Takuya Angel'i (Takuya Sawada koos abikaasa Akikoga), Kunihiko Morinaga, Suzuki Takayuki loomingust

Escrita científica de alunos de graduação em química: análise de relatórios de laboratório

Directory of Open Access Journals (Sweden)

Jane Raquel Silva de Oliveira

2010-01-01

Full Text Available The purpose of this study was to analyze written arguments found within laboratory reports by undergraduate students in a practical inorganic chemistry course. The quality of students' argumentation was analyzed based on the argumentation model developed by Kelly and Takao. Students presented scientific arguments grounded in data and building toward theoretical assertions. This indicates that students have some understanding of the rhetorical power of data in their explanations. The findings of this study also support the idea that Kelly and Takao's model is effective in other disciplines and in other rhetorical tasks distinct from those originally analyzed by them in their domain of oceanography.

KSC-03PD-2333

Science.gov (United States)

2003-01-01

KENNEDY SPACE CENTER, FLA. STS-114 Pilot James Kelly talks with Bren Wade, captain of the Liberty Star, one of the SRB Retrieval Ships docked at Hangar AF on the Banana River. Kelly and other crew members Commander Eileen Collins and Mission Specialists Soichi Noguchi and Stephen Robinson toured the ships. Noguchi is with the Japanese space agency NASDA. Mission STS-114 will carry the MultiPurpose Logistics Module (MPLM) Raffaello and External Stowage Platform 2 to the International Space Station. The MPLM will contain supplies and equipment. Another goal of the mission is to remove and replace a Control Moment Gyro. Launch date for mission STS-114 is under review.

Beta-hydroxy-beta-methyl-butyrate blunts negative age-related changes in body composition, functionality and myofiber dimensions in rats

Science.gov (United States)

2012-01-01

Purpose To determine the effects of 16 wk. of beta-hydroxy-beta-methylbutyrate (HMB) administration on age-related changes in functionality and diffusion tensor imaging (DTI) determined myofiber dimensions. Methods Twelve young (44 wk.), 6 middle-aged (60 wk.), 10 old (86 wk.), and 5 very old (102 wk.) male Fisher-344 rat's body composition and grip strength were assessed at baseline. Following, 6 young, 6 middle-aged, 5 old and 5 very old rats were sacrificed for baseline myofiber dimensions and gene transcript factor expression in the soleus (SOL) and gastrocnemius (GAS). The remaining 6 young and 5 old rats were given HMB for 16 wk. and then sacrificed. Results Fat mass increased in the middle-aged control condition (+49%) but not the middle-aged HMB condition. In addition, fat mass declined (-56%) in the old HMB condition but not the old control condition. Normalized strength declined and maintained respectively in the control and HMB conditions from 44 to 60 wk. and increased (+23%) (p HMB condition. Declines occurred in myofiber size in all muscles from 44 to 102 wk. in the control condition(-10 to -15%), but not HMB condition. Atrogin-1 mRNA expression in the SOL and GAS muscles was greater in the 102-wk control condition than all other conditions: SOL (+45%) and GAS (+100%). This elevation was blunted by HMB in the 102 wk. old SOL. There was a condition effect in the SOL for myogenin, which significantly increased (+40%) only in the 102-wk. HMB group relative to the 44-wk. group. Conclusions HMB may blunt age-related losses of strength and myofiber dimensions, possibly through attenuating the rise in protein breakdown. PMID:22512917

Effect of nickel chloride on hepatic lipid peroxidation and glutathione concentration in mice

DEFF Research Database (Denmark)

Andersen, H R; Andersen, O

1989-01-01

Intraperitoneal administration of nickel chloride enhanced hepatic lipid peroxidation (HLP) in 6-wk-old and 8-12-wk-old male CBA-mice but not in 3-wk-old mice. Nickel chloride administration depleted hepatic GSH in 8-12-wk-old mice but not in the younger age groups. After 300 mumol NiCl2/kg...

Complete Mitochondrial Genome Sequencing of a Burial from a Romano–Christian Cemetery in the Dakhleh Oasis, Egypt: Preliminary Indications

Directory of Open Access Journals (Sweden)

J. Eldon Molto

2017-10-01

Full Text Available The curse of ancient Egyptian DNA was lifted by a recent study which sequenced the mitochondrial genomes (mtGenome of 90 ancient Egyptians from the archaeological site of Abusir el-Meleq. Surprisingly, these ancient inhabitants were more closely related to those from the Near East than to contemporary Egyptians. It has been accepted that the timeless highway of the Nile River seeded Egypt with African genetic influence, well before pre-Dynastic times. Here we report on the successful recovery and analysis of the complete mtGenome from a burial recovered from a remote Romano–Christian cemetery, Kellis 2 (K2. K2 serviced the ancient municipality of Kellis, a village located in the Dakhleh Oasis in the southwest desert in Egypt. The data were obtained by high throughput sequencing (HTS performed independently at two ancient DNA facilities (Armed Forces DNA Identification Laboratory, Dover, DE, USA and Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA. These efforts produced concordant haplotypes representing a U1a1a haplogroup lineage. This result indicates that Near Eastern maternal influence previously identified at Abusir el-Meleq was also present further south, in ancient Kellis during the Romano–Christian period.

Diet-induced weight loss and exercise alone and in combination enhance the expression of adiponectin receptors in adipose tissue and skeletal muscle, but only diet-induced weight loss enhanced circulating adiponectin

DEFF Research Database (Denmark)

Christiansen, Tore; Paulsen, Søren K; Bruun, Jens M

2009-01-01

and adiponectin receptors (AdipoR) in adipose tissue (AT) and skeletal muscle (SM). Design and Methods: Seventy-nine obese males and females were randomized into the following: 1) exercise only (12 wk of exercise without diet restriction); 2) hypocaloric diet [8 wk of very low energy diet (600 kcal/d) followed...... by 4 wk with a weight maintenance diet]; and 3) hypocaloric diet and exercise (DEX; 8 wk very low energy diet 800 kcal/d followed by 4 wk weight maintenance diet combined with exercise throughout the 12 wk). Blood samples and biopsies from sc abdominal AT and SM were collected at baseline and after 12...... in all three groups (all P hypocaloric diet groups (both P

Effect of Fenbendazole on Three Behavioral Tests in Male C57BL/6N Mice

OpenAIRE

Gadad, Bharathi S; Daher, João P L; Hutchinson, Eric K; Brayton, Cory F; Dawson, Ted M; Pletnikov, Mikhail V; Watson, Julie

2010-01-01

Pinworms are highly contagious parasites of laboratory rodents that often are treated with fenbendazole. To our knowledge, the effect of fenbendazole at therapeutic dosages on behavioral tests in mice has not been evaluated. Here we studied 6-wk-old male C57BL/6N mice. We compared the behavior of control mice (fed regular diet) with 3 groups of mice treated with dietary fenbendazole. Treatment groups were 4 wk of fenbendazole, 2 wk of fenbendazole followed by 2 wk of regular diet, and 2 wk of...

Dynamic changes of photorecrptor layer in eyes with acute central serous chorioretinopathy after laser treatment by fourier-domain optical coherence tomography%应用 FD-OCT 动态观察急性 CSCR激光后光感受器层的变化

Institute of Scientific and Technical Information of China (English)

周丽琴; 王毅; 王晟; 孔琛柯

2014-01-01

AIM:To dynamically observe the feeling change of the photorecrptor layer in the eyes with acute central serous chorioretinopathy ( CSCR ) krypton laser treatment by fourier- domain optical coherence tomography ( FD -OCT ), and to study their correlation with the chang of vision. METHODS: This is a retrospective case series study. The clinical diagnosis of 52 patients with monocular initial onset of central serous chorioretinopathy, krypton laser photocoagulation before treatment, after 1,2,4,6,8wk,6mo, FD - OCT were performed to observe the morphological changes characteristic of photoreceptor layer and changes in vision. RESULTS: After 1wk treatment, all cases were improved;2wk,6 cases were cured;4wk,38 cases were cured;6wk,41 cases were cured;8wk,45 cases were cured, the OCT showed macular retinal neuroepithelial layer ( RNL ) from fully absorbed;6mo with the same 8wk. Before and after treatment in patients with best corrected visual acuity and from the height difference between the macular region of RNL was statistically significant (P CONCLUSION:FD-OCT can dynamicaly observed acute central serous chorioretinopathy krypton laser treatment of photoreceptor ultrastruture changes. Photoreceptor layer of complete and incomplete best corrected visual acuity difference was statistically significant (P METHODS: This is a retrospective case series study. The clinical diagnosis of 52 patients with monocular initial onset of central serous chorioretinopathy, krypton laser photocoagulation before treatment, after 1, 2, 4, 6, 8wk, 6mo, FD - OCT were performed to observe the morphological changes characteristic of photoreceptor layer and changes in vision. RESULTS: After 1wk treatment, all cases were improved; 2wk, 6 cases were cured; 4wk, 38 cases were cured; 6wk, 41 cases were cured; 8wk, 45 cases were cured, the OCT showed macular retinal neuroepithelial layer ( RNL ) from fully absorbed; 6mo with the same 8wk. Before and after treatment in patients with best corrected

Myocardial 99mTc-sestamibi extraction and washout in hypertensive heart failure using an isolated rat heart

International Nuclear Information System (INIS)

Fukushima, Kenji; Momose, Mitsuru; Kondo, Chisato; Higuchi, Takahiro; Kusakabe, Kiyoko; Hagiwara, Nobuhisa

2010-01-01

Purpose: Myocardial mitochondria are the primary part of energy production for healthy cardiac contraction. And mitochondrial dysfunction would play an important role in progressive heart failure. In the recent years, myocardial washout of 99m Tc-sestamibi [( 99m Tc-hexakis-2-methoxy-2-methylpropyl isonitrile (MIBI)] has been introduced to be a potential marker in patients with heart failure. The objective of this study was to clarify MIBI extraction and washout kinetics using isolated perfusion system in hypertension induced model of myocardial dysfunction. Methods: Six-week-old Dahl-salt sensitive rats, allotted to 4 groups; a 5-week high-salt group (5wk-HS), 12-week high-salt group (12wk-HS) and two age-matched, low-salt diet control groups (5wk-LS and 12wk-LS). The rats in 5wk-HS and 12wk-HS groups were fed a high-salt diet (containing 8% NaCl). Cardiac function was examined by echocardiography before removing heart. Hearts were perfused according to the Langendorff method at a constant flow rate, in which 20-min MIBI washin was conducted followed by 25-min MIBI washout. Whole heart radioactivity was collected every sec by an external gamma detector. The myocardial extraction, K 1 (ml/min) and washout rate, k 2 (min -1 ) were generated. Results: High-salt diet groups showed significant high-blood pressure. Echocardiography revealed thickened LV walls in 5wk-HS, and reduced cardiac function in 12wk-HS, compared to each age-matched control group. K 1 showed no significant difference among all groups (5wk-HS: 2.36±1.07, 5wk-control: 2.59±0.28, 12wk-HS: 1.91±0.90, and 12wk-control: 2.84±0.57). k 2 in 5wk-HS was comparable to that in the age matched control group (0.00030±0.00039 vs -0.000010±0.00044), but it was increased remarkably in 18wk-HS compared to the age matched control group (0.0025±0.0011 vs 0.000025±0.000041, P<.01), and 5wk-HS (P<.01). Conclusion: In the course of hypertensive heart disease, MIBI washout was increased in the transitional state

Myocardial {sup 99m}Tc-sestamibi extraction and washout in hypertensive heart failure using an isolated rat heart

Energy Technology Data Exchange (ETDEWEB)

Fukushima, Kenji [Department of Cardiology, Tokyo Women' s Medical University, Tokyo 162-8666 (Japan); Department of Radiology, Johns Hopkins University, Baltimore, MD (United States); Momose, Mitsuru, E-mail: mmomose@rad.twmu.ac.j [Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women' s Medical University, Tokyo 162-8666 (Japan); Kondo, Chisato [Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women' s Medical University, Tokyo 162-8666 (Japan); Higuchi, Takahiro [Department of Radiology, Johns Hopkins University, Baltimore, MD (United States); Kusakabe, Kiyoko [Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women' s Medical University, Tokyo 162-8666 (Japan); Hagiwara, Nobuhisa [Department of Cardiology, Tokyo Women' s Medical University, Tokyo 162-8666 (Japan)

2010-11-15

Purpose: Myocardial mitochondria are the primary part of energy production for healthy cardiac contraction. And mitochondrial dysfunction would play an important role in progressive heart failure. In the recent years, myocardial washout of {sup 99m}Tc-sestamibi [({sup 99m}Tc-hexakis-2-methoxy-2-methylpropyl isonitrile (MIBI)] has been introduced to be a potential marker in patients with heart failure. The objective of this study was to clarify MIBI extraction and washout kinetics using isolated perfusion system in hypertension induced model of myocardial dysfunction. Methods: Six-week-old Dahl-salt sensitive rats, allotted to 4 groups; a 5-week high-salt group (5wk-HS), 12-week high-salt group (12wk-HS) and two age-matched, low-salt diet control groups (5wk-LS and 12wk-LS). The rats in 5wk-HS and 12wk-HS groups were fed a high-salt diet (containing 8% NaCl). Cardiac function was examined by echocardiography before removing heart. Hearts were perfused according to the Langendorff method at a constant flow rate, in which 20-min MIBI washin was conducted followed by 25-min MIBI washout. Whole heart radioactivity was collected every sec by an external gamma detector. The myocardial extraction, K{sub 1} (ml/min) and washout rate, k{sub 2} (min{sup -1}) were generated. Results: High-salt diet groups showed significant high-blood pressure. Echocardiography revealed thickened LV walls in 5wk-HS, and reduced cardiac function in 12wk-HS, compared to each age-matched control group. K{sub 1} showed no significant difference among all groups (5wk-HS: 2.36{+-}1.07, 5wk-control: 2.59{+-}0.28, 12wk-HS: 1.91{+-}0.90, and 12wk-control: 2.84{+-}0.57). k{sub 2} in 5wk-HS was comparable to that in the age matched control group (0.00030{+-}0.00039 vs -0.000010{+-}0.00044), but it was increased remarkably in 18wk-HS compared to the age matched control group (0.0025{+-}0.0011 vs 0.000025{+-}0.000041, P<.01), and 5wk-HS (P<.01). Conclusion: In the course of hypertensive heart disease, MIBI

77 FR 14832 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2012-03-13

... workers from Kelly Services. 81,269 Cummins Filtration, A Cookeville, TN...... December 11, 2011...,302 American Technical Huntington Station, February 6, 2011. Ceramics New York Office, NY. AVX...

78 FR 25305 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2013-04-30

..., Onin Staffing, etc. 82,617 YP Southeast Advertising & Tucker, GA March 27, 2012. Publishing LLC, YP... Enterprise Services, Policy Processing Service, Kelly Services I hereby certify that the aforementioned...

Pühak Tony Blair ehk võit on võit / Maris Lillak

Index Scriptorium Estoniae

Lillak, Maris, 1970-

2004-01-01

Lord Huttoni raportist, mis selgitas Briti relvaeksperdi David Kelly enesetapu asjaolusid. Raporti mõjust peaminister Tony Blairile ja meediakompaniile BBC. Vt. samas: Süüdi tunnistatud BBCd raputavad tagasiastumised

75 FR 70294 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2010-11-17

...,240 Baker Hughes Oilfield Broussard, LA......... June 8, 2009. Operations, Leased Workers from Kelly... Center. 74,726 Weldco-Beales Manufacturing Tacoma, WA October 12, 2009. 74,740 Bekaert Corporation, Vista...

78 FR 34672 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2013-06-10

..., LLC, Automotive Electronics and Interiors, Johnson Controls, Kelly Services etc. 82,609 Tesoro Hawaii... Operating Unit. 82,707 Delphi Corporation, Electronics and Flint, MI May 6, 2012. Safety Division, Securitas...

Katherine Brooke'ist / Tiina Lepiste

Index Scriptorium Estoniae

Lepiste, Tiina

2007-01-01

Ameerika teleseriaali "Vaprad ja ilusad" ("The Bold and the Beautiful") osatäitja Katherine Kelly Lang (Brooke). Artikli aluseks on Soap Opera Weekly ajakirjaniku Linda Susmani vestlus näitlejannaga

CANINE DISTEMPER VIRUS ANTIBODY TITERS IN DOMESTIC CATS AFTER DELIVERY OF A LIVE ATTENUATED VIRUS VACCINE.

Science.gov (United States)

Ramsay, Edward; Sadler, Ryan; Rush, Robert; Seimon, Tracie; Tomaszewicz, Ania; Fleetwood, Ellen A; McAloose, Denise; Wilkes, Rebecca P

2016-06-01

Three methods for delivering a live attenuated canine distemper virus (CDV) vaccine to domestic cats ( Felis catus ) were investigated, as models for developing vaccination protocols for tigers (Panthera tigris). Twenty domestic cats were randomly divided into four treatment groups: saline injection (negative controls); and oral, intranasal, and subcutaneous vaccinates. Cats were injected with saline or a CDV vaccine (Nobivac DP, Merck) at wk 0 and 4. Blood and nasal swabs were collected at wk 0 (prior to the initial vaccination) and weekly thereafter for 9 wk. Urine samples were collected on wk 1 to 9 after initial vaccination. Forty-nine weeks following the initial vaccination series, three cats from the subcutaneous group and three cats from the intranasal group were revaccinated. Blood was collected immediately prior, and 7 and 21 days subsequent to revaccination. Nasal swabs and urine samples were collected from each cat prior to wk 49 revaccination and daily for 7 days thereafter. Nasal swabs and urine were analyzed by quantitative PCR for vaccine virus presence. Sera were tested for CDV antibodies by virus neutralization. All cats were sero-negative for CDV antibodies at the beginning of the study, and saline-injected cats remained sero-negative throughout the study. A dramatic anamnestic response was seen following wk 4 subcutaneous vaccinations, with titers peaking at wk 6 (geometric mean = 2,435.5). Following wk 49 revaccination, subcutaneous vaccinates again mounted impressive titers (wk 52 geometric mean = 2,048). Revaccination of the intranasal group cats at wk 49 produced a small increase in titers (wk 52 geometric mean = 203). CDV viral RNA was detected in six nasal swabs but no urine samples, demonstrating low viral shedding postvaccination. The strong antibody response to subcutaneous vaccination and the lack of adverse effects suggest this vaccine is safe and potentially protective against CDV infection in domestic cats.

Depressor effect of the young leaves of Polygonum hydropiper Linn. in high-salt induced hypertensive mice.

Science.gov (United States)

Devarajan, Sankar; Yahiro, Eiji; Uehara, Yoshinari; Kuroda, Rieko; Hirano, Yoshio; Nagata, Kaori; Miura, Shinichiro; Saku, Keijiro; Urata, Hidenori

2018-06-01

A novel chymase inhibitor has been reported to have depressor effect in salt-induced hypertension. Therefore, we examined the hypothesis that chymase inhibitory dried young leaves of Polygonum hydropiper (PPH) or young leaves extract of Polygonum hydropiper (PHE) could reduce salt-induced hypertension. In this study, 8-wk old wild-type mice were allocated into three experiments and experiment I included groups, I- normal water drinking, II- high salt (2% NaCl) water (HSW) drinking, and III- HSW plus PPH (500 mg kg -1 , orally) for 12-wk. Blood pressure (BP) and heart rate (HR) were measured at baseline and weekly up to wk-12. In experiment II, mice were given HSW for 12-wk followed by 8-wk treatment with PPH plus HSW (62.5, 125, 250 and 500 mg kg -1 for groups I, II, III and IV, respectively). BP and HR were measured at baseline and monthly until wk-12, following weekly for 8-wk. Experiment III comprised of four groups of mice for 12-wk HSW and 8-wk treatment with PHE plus HSW (2.5, 5, 10 and 20 mg kg -1 for groups I-IV, respectively). BP and HR were measured at baseline and monthly up to wk-12, following weekly for 8-wk. Significant reduction in BP and HR were observed in mice treated with PPH (500 mg kg -1 ) compared to HSW control. PPH reduced BP and HR dose dependently in hypertensive mice and the higher dose showed maximum reduction. PHE at its maximum dose (20 mg kg -1 ) significantly suppressed BP and HR. Over all, we found that the young leaves of Polygonum hydropiper suppressed salt-induced hypertension. Copyright © 2018. Published by Elsevier Masson SAS.

Effect of maca supplementation on bovine sperm quantity and quality followed over two spermatogenic cycles.

Science.gov (United States)

Clément, C; Kneubühler, J; Urwyler, A; Witschi, U; Kreuzer, M

2010-07-15

Maca (Lepidium meyenii Walpers), is an Andean crop that grows between 3,800 and 4,500 m a.s.l. The persistent interest in this plant is based on its assumed effects on fertility of male mammals due to the prevalence of certain, partially specific, secondary compounds. The present study aimed at evaluating the effect of maca supplementation on quality and quantity of semen, mating behavior, and clinical status of peripubertal breeding bulls. The experiment followed a cross-over design lasting for 23 wk with 3 wk of adaptation and baseline measurements, and 2 x 10 wk of treatment feeding thus covering two times the complete 8-wk spermatogenic cycle. Seventy-eight 55 wk to 84 wk old breeding bulls received either no maca (control) or maca (233 mg dried hypocotyls/kg body weight/day) for 10 wk followed by 10 wk without maca (maca early) or maca only in the last 10 wk (maca late). Measurements were always made in the last 2 wk of each period. Apart from standard analyses, ejaculates were analyzed by flow cytometry. Data was evaluated by analysis of variance considering the repeated measurement structure of the data. Significant treatment by measurement period indicated direct or carry-over effects of maca. Maca supplementation had no direct effect on body weight, testes circumference, rectal temperature, mating behavior, and ejaculate volume. However, supplementing maca in the first 10 wk period increased the number of sperms in the second 10 wk period, i.e., when the animals no longer received maca. The DNA fragmentation index and the visually assessed motility of the sperms of bulls, that initially showed a borderline sperm quality, were significantly improved with early maca supplementation, while no such effect was observed in the two other groups. No effects occurred in the proportion of intact sperm plasma membranes or acrosomes or both. In conclusion, maca supplementation seems to improve sperm quantity and quality of bulls to a certain degree, while mating

Maternal inactivity: 45-year trends in mothers' use of time.

Science.gov (United States)

Archer, Edward; Lavie, Carl J; McDonald, Samantha M; Thomas, Diana M; Hébert, James R; Taverno Ross, Sharon E; McIver, Kerry L; Malina, Robert M; Blair, Steven N

2013-12-01

To examine 45-year trends in time use and physical activity energy expenditure (PAEE) in a nationally representative sample of US mothers. We quantified time allocation to physical activity (PA), sedentary behaviors (SED), and PAEE from 1965 to 2010 in mothers with older children (MOC) (>5 to ≤18 years) and mothers with younger children (MYC) (≤5 years). Physical activity was the sum of time allocated to housework, child care, laundry, food preparation, postmeal cleanup, and exercise. Sedentary behavior was the sum of time spent in a vehicle and using screen-based media. Physical activity energy expenditure was calculated using body weights from national surveys and metabolic equivalents. From 1965 to 2010, the time allocated to PA decreased by 11.1 h/wk (from 32.0 to 20.9 h/wk) in MOC and by 13.9 h/wk (from 43.6 to 29.7 h/wk) in MYC. The time spent in SED increased by 7.0 h/wk in MOC (from 17.7 to 24.7 h/wk) and increased by 5.7 h/wk in MYC (from 17.0 to 22.7 h/wk). Physical activity energy expenditure decreased by 1237.6 kcal/wk (176.8 kcal/d) in MOC (from 5835.3 to 4597.7 kcal/wk), and in MYC, PAEE decreased by 1572.5 kcal/wk (224.6 kcal/d), from 7690.5 to 6118.0 kcal/wk. There was a significant reallocation of time by mothers from PA (eg, housework) to SED (eg, watching television) between 1965 and 2010. Given the essential role of PA for health and the potential for the intergenerational transmission of obesity and obesogenic behaviors, these results suggest that maternal inactivity may be an important target for the primary prevention of chronic noncommunicable diseases and obesity. Copyright © 2013 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

Downregulation of transient receptor potential M6 channels as a cause of hypermagnesiuric hypomagnesemia in obese type 2 diabetic rats.

Science.gov (United States)

Takayanagi, Kaori; Shimizu, Taisuke; Tayama, Yosuke; Ikari, Akira; Anzai, Naohiko; Iwashita, Takatsugu; Asakura, Juko; Hayashi, Keitaro; Mitarai, Tetsuya; Hasegawa, Hajime

2015-06-15

We assessed the expression profile of Mg(2+)-transporting molecules in obese diabetic rats as a cause of hypermagnesiuric hypomagnesemia, which is involved in the development of insulin resistance, hypertension, and coronary diseases. Kidneys were obtained from male Otsuka Long-Evans Tokushima fatty (OLETF) and Long-Evans Tokushima Otsuka (LETO) obese diabetic rats at the ages of 16, 24, and 34 wk. Expression profiles were studied by real-time PCR and immunohistochemistry together with measurements of urine Mg(2+) excretion. Urine Mg(2+) excretion was increased in 24-wk-old OLETF rats and hypomagnesemia was apparent in 34-wk-old OLETF rats but not in LETO rats (urine Mg(2+) excretion: 0.16 ± 0.01 μg·min(-1)·g body wt(-1) in 24-wk-old LETO rats and 0.28 ± 0.01 μg·min(-1)·g body wt(-1) in 24-wk-old OLETF rats). Gene expression of transient receptor potential (TRP)M6 was downregulated (85.5 ± 5.6% in 34-wk-old LETO rats and 63.0 ± 3.5% in 34-wk-old OLETF rats) concomitant with Na(+)-Cl(-) cotransporter downregulation, whereas the expression of claudin-16 in tight junctions of the thick ascending limb of Henle was not different. The results of the semiquantitative analysis of immunohistochemistry were consistent with these findings (TRPM6: 0.49 ± 0.04% in 16-wk-old LETO rats, 0.10 ± 0.01% in 16-wk-old OLETF rats, 0.52 ± 0.03% in 24-wk-old LETO rats, 0.10 ± 0.01% in 24-wk-old OLETF rats, 0.48 ± 0.02% in 34-wk-old LETO rats, and 0.12 ± 0.02% in 34-wk-old OLETF rats). Gene expression of fibrosis-related proinflammatory cytokines as well as histological changes showed that the hypermagnesiuria-related molecular changes and tubulointerstitial nephropathy developed independently. TRPM6, located principally in distal convoluted tubules, appears to be a susceptible molecule that causes hypermagnesiuric hypomagnesemia as a tubulointerstitial nephropathy-independent altered tubular function in diabetic nephropathy. Copyright © 2015 the American Physiological

PENGARUH PENDIDIKAN KEWIRAUSAHAAN DAN LINGKUNGAN KELUARGA TERHADAP JIWA KEWIRAUSAHAAN SISWA AKUNTANSI SMKN 1 DEMAK TAHUN 2016

Directory of Open Access Journals (Sweden)

Rokhimah Rokhimah

2017-06-01

Full Text Available Berdasarkan hasil observasi dan penelusuran lulusan menunjukan tingkat jiwa kewirausahaan siswa Akuntansi SMKN 1 Demak masih rendah. Hal ini belum sesuai dengan visi misi SMKN 1 Demak menyiapkan tamatan bertakwa berbudi luhur mempunyai etos kerja dan berjiwa wirausaha. Tujuan dari penelitian ini adalah untuk mengetahui bukti empiris pengaruh pendidikan kewirausahaan dan lingkungan keluarga terhadap jiwa kewirausahaan siswa Akuntansi SMKN 1 Demak tahun 2016. Populasi dalam penelitian ini adalah seluruh siswa Akuntansi SMKN 1 Demak tahun 2016 yang berjumlah 296 siswa. Jumlah sampel 173 siswa yang diambil menggunakan rumus Slovin. Pengambilan sampel dengan menggunakan proportional random sampling. Penelitian ini menggunakan angket sebagai alat pengumpulan data. Metode analisis yang digunakan adalah deskriptif persentase dan statistik inferensial. Hasil penelitian menunjukan pengaruh positif pendidikan kewirausahaan dan lingkungan keluarga terhadapa jiwa kewirausahaan siswa Akuntansi SMKN 1 Demak tahun 2016 secara simultan sebesar 57,8%. Terdapat pengaruh positif pendidikan kewirausahaan terhadap jiwa kewirausahaan siswa Akuntansi SMKN 1 Demak tahun 2016 secara parsial sebesar 25,1%. Terdapat pengaruh positif secara parsial lingkungan keluarga terhadap jiwa kewirausahaan siswa Akuntansi SMKN 1 Demak tahun 2016 sebesar 17,3%. Based obseravtion and graduation data show entrepreneurship spirit Accounting students SMKN 1 Demak are low, there not in line with vision and mission SMKN 1 Demak those are students have religious behavioristic, work spirit, and entrepreneurship spirit. The purpose this research is empirically to know the influence of entrepreneurship education and family environment on the entrepreneurial spirit Accounting students in SMKN 1 Demak. The populations all students of Accounting SMKN 1 Demak in 2016 , total 296 students. Total sample in this research are 173 students, there are from slovin formula. This study used a questionnaire

PENGARUH GITA GUTAWA SEBAGAI BRAND AMBASSADOR POND’S DALAM MEMPENGARUHI KEPUTUSAN PEMBELIAN (STUDI KASUS PADA MAHASISWI UNIVERSITAS TELKOM JURUSAN D3 MANAJEMEN PEMASARAN

Directory of Open Access Journals (Sweden)

Rennyta Yusiana

2016-03-01

Full Text Available Abstract - Promotion is one aspect that is important in marketing. Consumers are currently viewing a video or advertisement before buying a product. Apart from the functional or realistic appeal is also expected to attract emotionally advertising by using brand ambassadors. The purpose of this study was to determine whether there is a relationship characteristics Pond's brand ambassador (Gita Gutawa with consumer purchasing decisions. The population of this research is a student D3 Marketing Management totaling 178 Telkom University student. By using Slovin formula is obtained as a sample of 123 female students. Engineering samples are used are non-probability sampling technique purposive sampling types. The method used is a simple linear regression. Data collection techniques were performed using questionnaires distributed to the respondents. The results showed that the variable Gita Gutawa as brand ambassador and variable consumer purchasing decisions can be approved by the continuum line of 88.27% and 86.93% . Influence Gita Gutawa as brand ambassador in influencing purchasing decisions amounted to 32%.   Keywords: Advertising, Brand Ambassador, Purchase Decision.   Abstrak - Promosi merupakan salah satu aspek yang penting dalam sebuah pemasaran. Para konsumen saat ini melihat sebuah video atau iklan sebelum membeli suatu produk. Selain dari daya tarik fungsional atau realistik diharapkan pula iklan dapat menarik secara emosional dengan menggunakan brand ambassador. Tujuan dari penelitian ini adalah untuk mengetahui apakah ada hubungan karakteristik brand ambassador Pond’s (Gita Gutawa dengan keputusan pembelian konsumen. Populasi penelitian ini adalah mahasiswi D3 Manajemen Pemasaran Universitas Telkom yang berumlah 178 mahasiswi. Dengan menggunakan rumus Slovin didapatkan sebanyak 123 mahasiswi yang menjadi sampel. Teknik sampel yang digunakan adalah teknik non probability sampling jenis purposive sampling. Metode penelitian yang

Anatomy of a Cancer Treatment Scam

Medline Plus

Full Text Available ... Joshua Phillips Rohit Chopra Rebecca Kelly Slaughter Bureaus & Offices Bureau of Competition Bureau of Consumer Protection Bureau of Economics Office of Congressional Relations Office of Equal Employment Opportunity ...

Composite materials for aircraft structures

National Research Council Canada - National Science Library

Baker, A. A; Dutton, Stuart; Kelly, Donald

2004-01-01

... materials for aircraft structures / Alan Baker, Stuart Dutton, and Donald Kelly- 2nd ed. p. cm. - (Education series) Rev. ed. of: Composite materials for aircraft structures / edited by B. C. Hos...

Plaadid / Mart Normet

Index Scriptorium Estoniae

Normet, Mart, 1979-

2005-01-01

Uutest heliplaatidest Kelly Osbourne "Sleeping in the Nothing", The Black Eyed Peas "Monkey Business", Faith Evans "The First Lady", Joni Mitchell "Songs of a Prairie Girl", Mylene Farmer "Que L'ombre"

Graafika Filharmoonias : Harry Liivrand soovitab / Harry Liivrand

Index Scriptorium Estoniae

Liivrand, Harry, 1961-

2004-01-01

Alustatakse regulaarse kunstinäituse programmiga Estonia Kontserdisaalis. Avatakse graafikanäitus "Lähenemised" (koostaja Vappu Vabar). Osalevad Marje Üksine, Reti Saks, Maria-Kristiina Ulas, Kelli Kagovere, Naima Neidre jt

A Proposal for Kelly CriterionBased Lossy Network Compression

Science.gov (United States)

2016-03-01

detection applications. Most of these applications only send alerts to the central analysis servers. These alerts do not provide the forensic capability...based intrusion detection systems. These systems tend to examine the indi- vidual system’s audit logs looking for intrusive activity. The notable

Duell diktaatoriga / Juri Hashtshevatski ; interv. Kelly Grossthal, Maari Ross

Index Scriptorium Estoniae

Hashtshevatski, Juri

2007-01-01

Tallinnas linastub esimene Eesti-Valgevene ühistöö "Kalinovski väljak", dokumentaalfilm Valgevene kuulsaima režissööri pikalt kestnud ja ohtlikust konfliktist diktaator Lukashenkaga. Poliitilisest olukorrast Valgevenes, president Aleksandr Lukashenkast

Elav kunstiteos : sõna otseses mõttes / Kelly Kipper

Index Scriptorium Estoniae

Kipper, Kelly

2011-01-01

Serbia kunstniku Marina Abramovići (sünd. 1946) elust ja loomingust. Performance'itest "Rütm 10", "Rütm 5", "Rütm 0", "The Artist is Present", "The Life and Death of Marina Abramović". Koostööst saksa kunstniku Ulayga (Uwe Laysiepen)

Patendiinfo kasutamine teadustegevuse indikaatorina Eestis / Aleksei Kelli, Tõnis Mets

Index Scriptorium Estoniae

Kelli, Aleksei, 1977-

2017-01-01

Patendiinfo kasutamisest teadustegevuse indikaatorina Eestis. Patendiinfo teadusindikaatoritest, teadustöö kvaliteeti iseloomustavast patendiinfost ja patendiinfo kasutamise regulatiivsest raamistikust

Wild kernels for higher K-theory of division and semi-simple algebras

International Nuclear Information System (INIS)

Quo Xuejun; Kuku, Aderemi

2003-06-01

Let Σ be a semi-simple algebra over a number field F. In this paper, we prove that for all n ≥ 0, the wild kernel WK n (Σ):Ker(K n (Σ) → Π finiteυ K n (Σ υ )) is contained in the torsion part of the image of the natural homomorphism K n (Λ) → K n (Σ), where Λ is a maximal order in Σ. In particular, WK n (Σ) is finite. In the process, we prove that if Λ is a maximal order in a central division algebra D over F, then the kernel of the reduction map K 2n-1 (Λ) → π υ Π finiteυ K 2n-1 (d υ ) is finite. In paragraph 3 we investigate the connections between WK n (D) and div(K n (D)) and prove that divK 2 (Σ) is a subset of WK 2 (Σ); if the index of D is square free, then div(K 2 (D)) ≅ div(K 2 (F)), WK 2 (F) ≅ WK 2 (D) and vertical bar WK 2 (D)/div(K 2 (D)) vertical bar ≤ 2. Finally we prove that if D is a central division algebra over F with [D : F] = m 2 , then (1) div(K n (D)) l = WK n (D) l for all odd primes I and n ≤ 2; (2) if I does not divide m, then div(K 3 (D)) l = WK 3 (D) l = 0; (3) if F = Q and I does not divide m, then div(K n (D)) l is a subset of WK n (D) l for all n. (author)

Plaadid / Immo Mihkelson

Index Scriptorium Estoniae

Mihkelson, Immo, 1959-

2003-01-01

Uutest plaatidest "Chicago", "1 Love", Therese "Acapulco", Soriba Kouyate "Live in Montreux", Jimi Hendrix "Blue Wild Angel", Asian Dub Foundation "Enemy Of The Enemy", Abdullah Ibrahim "African Magic", Kelly Osbourne "Shut Up"

Effects of the tricothecene mycotoxin diacetoxyscirpenol on egg production of broiler breeders.

Science.gov (United States)

Brake, J; Hamilton, P B; Kittrell, R S

2002-12-01

Three experiments were conducted to determine the effects of 4,15-diacetoxyscirpenol (DAS) on egg quality and egg production of broiler breeders. In Experiment 1, feed containing 0, 1.25, 2.5, or 5.0 mg DAS/ kg was fed from 67 to 69 wk of age followed by a 3-wk recovery period on a slat-litter floor. In Experiment 2, individually caged broiler breeder females were studied from 23 to 31 wk of age. The basal diet containing 0, 5, 10, or 20 mg DAS/kg was fed from 25 to 27 wk of age. In Experiment 3, individually caged broiler breeder hens were studied from 23 to 32 wk of age. DAS was fed at levels of 0 (basal), 5, 10, and 20 mg DAS/kg for 2 wk beginning at Week 24, followed by the basal breeder diet for 7 wk. Egg production was not affected by levels of up to 5 mg DAS/kg in the older hens of Experiment 1. When fed from 25 to 27 wk of age in Experiment 2, DAS decreased egg production at the 20 mg/kg level only. When fed from 24 to 25 wk of age in Experiment 3, DAS had no significant effect on egg production or egg quality. Short-term consumption of DAS at levels that might naturally occur appears to have little effect on broiler breeder egg production.

Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats.

Science.gov (United States)

Linden, Melissa A; Meers, Grace M; Ruebel, Meghan L; Jenkins, Nathan T; Booth, Frank W; Laughlin, M Harold; Ibdah, Jamal A; Thyfault, John P; Rector, R Scott

2013-05-01

Physical activity-induced prevention of hepatic steatosis is maintained during short-term (7-day) transitions to an inactive state; however, whether these protective effects are present under a longer duration of physical inactivity is largely unknown. Here, we sought to determine whether previous physical activity had protective effects on hepatic steatosis and metabolic health following 4 wk of physical inactivity. Four-week old, hyperphagic, male Otsuka Long-Evans Tokushima fatty (OLETF) rats were randomly assigned to either a sedentary group for 16 wk (OLETF-SED), given access to running wheels for 16 wk with wheels locked 5 h (OLETF-WL5hr) or given access to running wheels for 12 wk with wheels locked 4 wk (OLETF-WL4wk) prior to death. Four weeks of physical inactivity caused hepatic steatosis development, but liver triglycerides remained 60% lower than OLETF-SED (P inactivity, whereas markers of fatty acid uptake and lipogenesis remained relatively suppressed following 4 wk of inactivity. In addition, 4 wk of inactivity caused a complete loss of activity-induced increases in serum IL-6 and reductions in regulated upon activation, normal T-cell expressed, and secreted (RANTES), and a partial loss in reductions in leptin, monocyte chemoattractant protein-1, and TNF-α. In conclusion, 4 wk of physical inactivity does not result in a complete loss in physical activity-induced benefits but does cause deterioration in the liver phenotype and overall metabolic health in hyperphagic OLETF rats.

Uji Ketergunaan Layanan Antarmuka Magister Management Digital Library (MM-Digilib Perpustakaan Magister Manajemen Fakultas Ekonomi Universitas Indonesia

Directory of Open Access Journals (Sweden)

Sri Sugianti

2016-01-01

Full Text Available A digital library is an advancement of a conventional library. Wider role of a digital library lies in its ability to give support for service via virtual/electronic/digital network. Through its revolutionary presence, a digital library needs a testfor development. One of the tests that can be used is usqge test of interface service of magister management Digital Library (MM-Digilib at Magister Management of Faculty of Economics, University of Indonesia. Based on theformula of Slovin and Nomogram Henry King, there are 8I valid samples out of 651 of master students accessing digital theses at Magister Management Library, Faculty of Economics, University of Indonesia. Out of indicators of usage test - efficiency, effictiveness, ease ofuse and ease ofinteraction of MM-Digilib is in general relatively good. Yet it needs to improve thefunction of Advanced Search in order to assist and shorten time in searching.

PENGARUH PERSEPSI TENTANG PRAKTIK KERJA LAPANGAN, INFORMASI DUNIA KERJA DAN MOTIVASI MEMASUKI DUNIA KERJA TERHADAP KESIAPAN KERJA SISWA SMK

Directory of Open Access Journals (Sweden)

Yuyun Kusnaeni

2016-02-01

Full Text Available Tujuan penelitian ini yaitu, untuk mengetahui pengaruh persepsi tentang praktik kerja lapangan, informasi dunia kerja dan motivasi memasuki dunia kerja terhadap kesiapan kerja siswa SMK Bhakti Persada Kendal. Populasi dalam penelitian ini adalah seluruh siswa kelas XII SMK Bhakti Persada Kendal yang berjumlah 202 siswa. Jumlah sampel yang digunakan dalam penelitian ini adalah 134 siswa, yang diperoleh dengan menggunakan rumus slovin.Metode pengumpulan data dengan menggunakan kuesioner. Analisis data menggunakan analisis deskriptif persentase dan analisis regresi berganda dengan menggunakanSPSS for Windows versi 16. Berdasarkan hasil penelitian, menunjukkan bahwa ada pengaruh positif praktik kerja lapangan terhadap kesiapan kerja siswa0.000 0.05, there was the effect ofjobs information on students' job readiness 0.013 <0.05, there was the influence of motivation to enter the workforce to the job readiness of students 0,000 <0,05 so Ha1, Ha2 and Ha3 accepted.

Efficacy of alpha-cypermethrin and lambda-cyhalothrin applications to prevent Aedes breeding in tires.

Science.gov (United States)

Pettit, William J; Whelan, Peter I; McDonnell, Joseph; Jacups, Susan P

2010-12-01

The efficacy of alpha-cypermethrin (Cyperthor) and lambda-cyhalothrin (Demand) to prevent mosquito larval colonization of water-containing receptacles was investigated using 2 differing applications in disused car tires in Darwin, Australia. Insecticide treatments were applied uniformly to the inside surfaces of 2 categories of tires: 1) dry tires that were partially filled with water 24 h after spraying and 2) wet tires partially filled with water prior to spraying. All mosquito larvae, pupae, and dead adults were collected from the treatment and control tires weekly over the 24-wk study period and were later identified to species in the laboratory. Control tires were colonized by Aedes notoscriptus in wk 2 and by Culex quinquefasciatus in wk 4. Aedes notoscriptus failed to colonize any alpha-cypermethrin-treated tires until wk 22 and did not colonize any lambda-cyhalothrin-treated tires during the 24-wk trial. Culex quinquefasciatus colonized alpha-cypermethrin and lambda-cyhalothrin-treated tires from wk 11 and wk 15, respectively. These results indicate both insecticides using either application method can prevent colonization of Ae. notoscriptus for at least 20 wk and demonstrate great potential for the prevention of breeding in receptacles for other receptacle-breeding Aedes species, such as the dengue vectors, Ae. aegypti and Ae. albopictus.

Effect of dry period length on milk production in subsequent lactation

DEFF Research Database (Denmark)

Sørensen, J.T.; Enevoldsen, Carsten

1991-01-01

, two treatments were compared within herd. Compared with a 7-wk planned dry period, a 3-wk decrease lowered the level of milk production by 2.8 kg of 4% FCM/d in the first 84 d of the subsequent lactation, whereas a 3-wk increase raised the level of milk production by .5 kg/d. In the first 168 d......The effect of planned dry period lengths of 4, 7, and 10 wk on subsequent lactational yield was estimated with 366 cows in an experiment in which dry period was manipulated independently of milk yield prior to drying off. In two herds, all three treatments were compared within herd; in six herds...... of the subsequent lactation, the difference between 4-wk and 7-wk planned dry periods was 2.7 kg/d, and the difference between 7- and 10-wk periods was .4 kg/d. There was no indication of interaction among planned dry period length and lactation number, days open in previous lactation, previous milk yield, breed...

The formation of rats' choroidal neovascularization induced by acrolein

Directory of Open Access Journals (Sweden)

Guan-Feng Wang

2016-04-01

Full Text Available AIM:To investigate the formation of rats' choroidal neovascularization(CNVinduced by acrolein. METHODS:Twelve Sprague-Dawley rats were randomly divided into three groups. Acrolein 200μL(2.5 mg/kg/dwas poured into the rats' stomach for 4wk as acrolein 4wk and for 8wk as acrolein 8wk group. The same volume of fresh water was also done to the rats as the control group. Remove all eye balls and embed into paraffin with HE staining.RESLUTS:The RPE-Bruch membrane was intact with no obvious abnormality in the control group and acrolein 4wk group. Lost in the continuity of RPE and the movement of choroidal neovascularization were found in the acrolein 8wk. CONCLUSION:The long time use of acrolein can induce the formation of choroial neovascularization in rats.

76 FR 19468 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2011-04-07

... Services and Kelly Services. 75,274 Abbott Laboratories, Abbott Park, IL....... February 14, 2010... Moines, IA........ January 28, 2010. Inc., D/B/A UPS; Des Moines Billing Site. 75,156 Abbott Point of...

Exposure to biomass smoke as a risk factor for oesophageal and ...

African Journals Online (AJOL)

Exposure to biomass smoke as a risk factor for oesophageal and gastric cancer in low-income populations: A systematic review. Violet Kayamba, Douglas C. Heimburger, Douglas R. Morgan, Masharip Atadzhanov, Paul Kelly ...

Heavy Metals in Soils and Tomatoes Grown in Urban Fringe ...

African Journals Online (AJOL)

user

4Dept. of Industrial Safety and Environmental Management, Delta State School of Marine Technology, Warri, Nigeria. ... nutrients, which are usually in short supply (Thompson and Kelly, 1990). ..... Health risk assessment of ... food chains.

Pop / Mart Juur

Index Scriptorium Estoniae

Juur, Mart, 1964-

2003-01-01

Heliplaatidest: The Donnas "Spend The Night", RZA "The World According To RZA", Mew "Frengers", Blur "Think Tank", Coloma "Finery", Styrofoam "I'm What's There To Show That Something's Missing", R. Kelly "Chocolate Factory"

SHORT AND LONG TERM EFFECTS OF HIGH-INTENSITY INTERVAL TRAINING ON HORMONES, METABOLITES, ANTIOXIDANT SYSTEM, GLYCOGEN CONCENTRATION AND AEROBIC PERFORMANCE ADAPTATIONS IN RATS

Directory of Open Access Journals (Sweden)

Gustavo Gomes De Araujo

2016-10-01

Full Text Available The purpose of the study was to investigate the effects of short and long term High-Intensity Interval Training (HIIT on anaerobic and aerobic performance, creatinine, uric acid, urea, creatine kinase, lactate dehydrogenase, catalase, superoxide dismutase, testosterone, corticosterone and glycogen concentration (liver, soleus and gastrocnemius. The Wistar were separated in two groups: HIIT and sedentary/control (CT. The lactate minimum (LM was used to evaluate the aerobic and anaerobic performance (AP (baseline, 6 and 12 wk. The lactate peak determination consisted of two swim bouts at 13% of body weight (bw: 1 30 s of effort; 2 30 s of passive recovery; 3 exercise until exhaustion (AP. Tethered loads equivalent to 3.5, 4.0, 4.5, 5.0, 5.5 and 6.5% bw were performed in incremental phase. The aerobic capacity in HIIT group increased after 12 wk (5.2±0.2 % bw in relation to baseline (4.4±0.2 % bw, but not after 6 wk (4.5±0.3 % bw. The exhaustion time in HIIT group showed higher values than CT after 6 (HIIT= 58±5 s; CT=40±7 s and 12 wk (HIIT=62±7 s; CT=49±3 s. Glycogen (mg/100mg increased in gastrocnemius for HIIT group after 6 wk (0.757±0.076 and 12 wk (1.014±0.157 in comparison to baseline (0.358±0.024. In soleus, the HIIT increased glycogen after 6 wk (0.738±0.057 and 12 wk (0.709±0.085 in comparison to baseline (0.417±0.035. The glycogen in liver increased after HIIT 12 wk (4.079±0.319 in relation to baseline (2.400±0.416. The corticosterone (ng/mL in HIIT increased after 6 wk (529.0±30.5 and reduced after 12 wk (153.6±14.5 in comparison to baseline (370.0±18.3. In conclusion, long term HIIT enhanced the aerobic capacity, but short term (6wk was not enough to cause aerobic adaptations. The anaerobic performance increased in HIIT short and long term compared with CT, without differences between HIIT short and long term. Furthermore, the glycogen super-compensantion increased after short and long term HIIT in comparison to

Short communication: Effect of straw inclusion rate in a dry total mixed ration on the behavior of weaned dairy calves.

Science.gov (United States)

Groen, M J; Steele, M A; DeVries, T J

2015-04-01

The primary objective of this study was to determine the effect of straw inclusion levels on the feeding behavior of young, weaned calves adapted to a dry total mixed ration (TMR) composed of a multitextured concentrate and chopped straw. A secondary objective was to determine how developed feeding patterns persist after calves were switched to a conventional silage-based diet. Ten Holstein bull calves (91 ± 2.4d of age, weighing 136 ± 12.3 kg) were assigned to 1 of 2 treatments: a TMR containing [dry matter (DM) basis] either (1) 85% concentrate and 15% chopped straw for 10 wk (wk 1 to 10) or (2) 85% concentrate and 15% chopped straw for 5 wk (wk 1 to 5), then 70% concentrate and 30% chopped straw for 5 wk (wk 6 to 10). After 10 wk, all animals were transitioned to a TMR containing (DM basis) 42.3% corn silage and 57.7% haylage for 2 wk (wk 11 to 12). During wk 1 to 5, all calves had similar DMI (5.5 kg/d), average daily gain (1.7 kg/d), feed efficiency (3.5 kg of DM/kg of gain), and eating time (151.9 min/d). During wk 6 to 10, calves transitioned to the 70% diet ate less DM (5.5 vs. 7.4 kg/d), grew more slowly (1.3 vs. 1.6 kg/d), sorted more against long forage particles (62.8 vs. 103.8%), and had greater feeding times (194.9 vs. 102.6 min/d). The difference in feeding time occurred only during the first 8 h after feed delivery. Despite similar DMI (5.2 kg/d) and average daily gain (1.1 kg/d) in wk 11 to 12, differences in behavior were observed resulting from previous diets. In wk 11 to 12, calves previously fed the 70% diet continued to have a longer meal immediately after feed delivery. Overall, the results indicate that diluting a dry TMR containing a multitextured concentrate and chopped straw with more straw resulted in calves spending more time feeding and having longer meals immediately after feed delivery; this feeding pattern carried over after calves were transitioned to a silage-based ration. Copyright © 2015 American Dairy Science Association

Maternal weight gain and associations with longitudinal fetal growth in dichorionic twin pregnancies: a prospective cohort study.

Science.gov (United States)

Hinkle, Stefanie N; Hediger, Mary L; Kim, Sungduk; Albert, Paul S; Grobman, William; Newman, Roger B; Wing, Deborah A; Grewal, Jagteshwar; Zhang, Cuilin; Buck Louis, Germaine M; Grantz, Katherine L

2017-12-01

Background: Maternal metabolic demands are much greater with twin gestations; however, there are no accepted recommendations for maternal weight gain in twin pregnancies. Objective: We assessed the association of maternal weight gain and fetal growth in dichorionic twins throughout pregnancy. Design: This was a prospective US cohort study ( n = 143, 2012-2013) of dichorionic twin pregnancies with known birth outcomes followed from enrollment (11-13 wk) and for ≤6 research visits throughout gestation. Maternal prepregnancy weight was self-reported, and current weight was measured at each research visit and abstracted from prenatal records. Fetal biometry was assessed by ultrasound at each research visit. Maternal weight and twin-pair fetal size trajectories across gestation were modeled. The adjusted associations between maternal weight gain from 0 to 13, 14 to 20, 21 to 27, and 28 to 34 wk and fetal growth at the subsequent week (i.e., 14, 21, 28, and 35 wk, respectively) were estimated with the use of linear regression. Results: The mean ± SD maternal weight gain from 0 to 13, 14 to 20, 21 to 27, and 28 to 34 wk was 2.8 ± 3.0 kg, 3.9 ± 1.2 kg, 3.8 ± 1.4 kg, and 4.4 ± 2.2 kg, respectively, with a total gain of 17.7 ± 7.4 kg. Maternal weight gain from 0 to 13 wk (first trimester) was not associated with fetal size at 14 wk. Maternal weight gain from 14 to 20 and 21 to 27 wk (second trimester) was significantly associated with increased fetal weight at 21 wk [increase of 10.5 g/kg maternal weight gain (95% CI: 1.2, 19.8 g)] and 28 wk [increase of 21.3 g/kg maternal weight gain (95% CI: 0.6, 42.0 g)]. Maternal weight gain from 14 to 20 wk was associated with increased twin abdominal circumference (AC) and biparietal diameter at 21 wk. Maternal weight gain from 21 to 27 wk was associated with increased femur and humerus lengths at 28 wk. Conclusion: Maternal weight gain was associated with dichorionic twin fetal growth in the second trimester only, driven by an

Matching the reaction-diffusion simulation to dynamic [18F]FMISO PET measurements in tumors: extension to a flow-limited oxygen-dependent model.

Science.gov (United States)

Shi, Kuangyu; Bayer, Christine; Gaertner, Florian C; Astner, Sabrina T; Wilkens, Jan J; Nüsslin, Fridtjof; Vaupel, Peter; Ziegler, Sibylle I

2017-02-01

Positron-emission tomography (PET) with hypoxia specific tracers provides a noninvasive method to assess the tumor oxygenation status. Reaction-diffusion models have advantages in revealing the quantitative relation between in vivo imaging and the tumor microenvironment. However, there is no quantitative comparison of the simulation results with the real PET measurements yet. The lack of experimental support hampers further applications of computational simulation models. This study aims to compare the simulation results with a preclinical [ 18 F]FMISO PET study and to optimize the reaction-diffusion model accordingly. Nude mice with xenografted human squamous cell carcinomas (CAL33) were investigated with a 2 h dynamic [ 18 F]FMISO PET followed by immunofluorescence staining using the hypoxia marker pimonidazole and the endothelium marker CD 31. A large data pool of tumor time-activity curves (TAC) was simulated for each mouse by feeding the arterial input function (AIF) extracted from experiments into the model with different configurations of the tumor microenvironment. A measured TAC was considered to match a simulated TAC when the difference metric was below a certain, noise-dependent threshold. As an extension to the well-established Kelly model, a flow-limited oxygen-dependent (FLOD) model was developed to improve the matching between measurements and simulations. The matching rate between the simulated TACs of the Kelly model and the mouse PET data ranged from 0 to 28.1% (on average 9.8%). By modifying the Kelly model to an FLOD model, the matching rate between the simulation and the PET measurements could be improved to 41.2-84.8% (on average 64.4%). Using a simulation data pool and a matching strategy, we were able to compare the simulated temporal course of dynamic PET with in vivo measurements. By modifying the Kelly model to a FLOD model, the computational simulation was able to approach the dynamic [ 18 F]FMISO measurements in the investigated

Influence of initial insulin dosage on blood glucose dynamics of children and adolescents with newly diagnosed type 1 diabetes mellitus.

Science.gov (United States)

Wang, Yi; Gong, Chunxiu; Cao, Bingyan; Meng, Xi; Wei, Liya; Wu, Di; Liang, Xuejun; Li, Wenjing; Liu, Min; Gu, Yi; Su, Chang

2017-05-01

To investigate the effect of initial insulin dosage on blood glucose (BG) dynamics, β-cell protection, and oxidative stress in type 1 diabetes mellitus. Sixty newly diagnosed type 1 diabetes mellitus patients were randomly assigned to continuous subcutaneous insulin infusions of 0.6 ± 0.2 IU/kg/d (group 1), 1.0 ± 0.2 IU/kg/d (group 2), or 1.4 ± 0.2 IU/kg/d (group 3) for 3 wk. BG was monitored continuously for the first 10 d and the last 2 d of wk 2 and 3. A total of 24-hour urinary 8-iso-PGF2α was assayed on days 8, 9, and 10. The occurrence and duration of the honeymoon period were recorded. Fasting C-peptide and glycosylated hemoglobin (HbA1c) were assayed after 1, 6, and 12 months of insulin treatment. BG decreased to the target range by the end of wk 3 (group 1), wk 2 (group 2), or wk 1 (group 3). The actual insulin dosage over the 3 wk, frequency of hypoglycemia on wk 1 and 2, and median BG at the end of wk 1 differed significantly, but not 8-iso-PGF2α and the honeymoon period in the three groups. No severe hypoglycemia event was observed in any patient, but there was significant difference in the first occurrence of hypoglycemia. Differences in initial insulin dosage produced different BG dynamics in wk 1, equivalent BG dynamics on wk 2 and 3, but had no influence on short- and long-term BG control and honeymoon phase. The wide range of initial insulin dosage could be chosen if guided by BG monitoring. © 2016 The Authors. Pediatric Diabetes published by John Wiley & Sons Ltd.

Survey of Wastewater Discharge, Eielson AFB, Alaska, EHL(K) 73-24

National Research Council Canada - National Science Library

Thomas, Jerry F; Pauls, Chester F

1973-01-01

This report contains the results of a wastewater survey at Eielson AFB, Alaska, conducted by the USAF Environmental Health Laboratories, Kelly AFB, Texas and McClellan AFB, CA, between 22 and 27 June 1973...

Synovial fluid analysis

Science.gov (United States)

Joint fluid analysis; Joint fluid aspiration ... El-Gabalawy HS. Synovial fluid analysis, synovial biopsy, and synovial pathology. In: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Kelly's Textbook of ...

Kui kapital veab alt, siis turvaliselt / Aleksander Tsapov

Index Scriptorium Estoniae

Tsapov, Aleksander

2006-01-01

Kuraatorinäitus "Kapital (see veab meid alt)" Tallinna Kunstihoones. Kuraator Simon Sheikh. Fia-Stina Sandlundi, Katya Sanderi, Oliver Ressleri, Ashley Hunti ja Susan Kelly&Stephen Mortoni töödest näitusel

Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on performance and metabolism of laying hens.

Science.gov (United States)

Chowdhury, S R; Smith, T K

2004-11-01

An experiment was conducted to evaluate the effects of feeding laying hens grains naturally contaminated with a combination of Fusarium mycotoxins. Parameters measured included performance, organ weights, and plasma chemistry. One hundred and forty-four, 45-wk-old laying hens were fed diets including: (1) control, (2) contaminated grains, and (3) contaminated grains + 0.2% polymeric glucomannan mycotoxin adsorbent (GMA) for a 12-wk period. The feeding of contaminated grains decreased feed consumption compared with controls in the first 4 wk. Feed consumption increased, however, from 4 to 8 wk and from 8 to 12 wk. The efficiency of feed utilization (feed consumption/egg mass) decreased compared with controls in the periods from 4 to 8 and from 8 to 12 wk when birds were fed contaminated grains. Supplementation with GMA decreased feed consumption and increased the efficiency of feed utilization in the period from 8 to 12 wk. Egg production and egg mass decreased in wk 4 and 8 compared with controls when contaminated grains were fed, whereas egg and eggshell weights decreased in the fourth wk. Plasma uric acid concentrations increased throughout the experiment and relative kidney weights increased at the end of the experiment compared with controls when birds were fed contaminated grains. The feeding of GMA prevented the elevation in uric acid concentrations and relative kidney weights. It was concluded that layer performance and metabolism were adversely affected by chronic feeding of a combination of Fusarium mycotoxins, and that GMA prevented many of these effects.

Wairakei tracer tests 1983

International Nuclear Information System (INIS)

McCabe, W.J.; Barry, B.J.

1984-05-01

Tracer tests, with and without, hot water reinjection into WK213 showed returns of tracer iodine-131; in wells in both the Waiora Valley and the eastern end of the field. The effect of reinjection at a rate of 200 cu. m/h was to reduce the arrived time from 15 to 7 days. Increasing the rate of reinjection into WK62 from 30 cu. m/h to 200 cu. m/h seemed to increase the initial velocity of the tracer wave and the distance it moved. However, returns were recorded only in the adjacent wells WK61 and WK63 with a very small, and three days delayed, response in WK43

Biological alterations resulting from chronic lung irradiation. III. Effect of partial 60Co thoracic irradiation upon pulmonary collagen metabolism and fractionation in syrian hamsters

International Nuclear Information System (INIS)

Pickrell, J.A.; Harris, D.V.; Hahn, F.F.; Belasich, J.J.; Jones, R.K.

1975-01-01

Radiation-induced changes in pulmonary collagen metabolism were studied in Syrian hamsters given multiple thoracic doses of 60 Co radiation to achieve cumulative exposures of 6000, 4000, and 2000 R. At 13 to 14 wk after initial exposure, 6000- and 4000-R exposures had increased incorporation of injected [ 14 C]proline into pulmonary collagenous protein which suggested an increased collagen synthesis. By 21 to 22 wk after exposure, increased pulmonary soluble collagen was noted. Increased pulmonary scarring was indicated by a variable increase in native collagen at 13 to 36 wk. A collection of alveolar macrophages at 7 to 8 wk followed by inflammation at 13 to 14 wk and a beginning of pulmonary fibrosis at 13 to 19 wk were noted. At 21 to 22 wk after exposure a somewhat more marked pulmonary fibrosis and some epithelialization were observed. Hemosiderin deposits were also observed at 35 to 36 wk after exposure, but pathologic processes were lessened by this time. The early activation of collagen synthesis presumably caused the radiation-induced fibrosis. Later, when collagen tended to accumulate, the synthetic rate was normal. The activation of collagen synthesis caused by external thoracic irradiation resembles that caused by thoracic irradiation from the internal emitter, 144 Ce. Moreover, it demonstrates the usefulness of monitoring collagen biosynthesis by [ 14 C]proline incorporation into the lung. (U.S.)

Relationship of adipocyte size to hyperphagia in developing male obese Zucker rats.

Science.gov (United States)

Vasselli, J R; Fiene, J A; Maggio, C A

1992-01-01

In growing male obese Zucker rats, hyperphagia reaches a maximum or "breakpoint" and declines at an earlier age with high fat than with chow-type diets. A serial adipose tissue biopsy technique was used to correlate changes of retroperitoneal adipocyte size and feeding behavior in 5- to 7-wk-old male lean and obese rats fed laboratory chow or a 35% fat diet until 30 wk of age. Although chow-fed groups had significantly greater cumulative intake, fat-fed groups had significantly greater body weight gain, retroperitoneal depot weight, and adipocyte number. Mean adipocyte size increased continuously in chow-fed groups but decreased over weeks 20-30 in fat-fed groups, reflecting increased adipocyte number. In fat-fed obese rats, hyperphagia reached a breakpoint at 11 wk and disappeared by 13 wk. In chow-fed obese rats, hyperphagia reached a breakpoint at 15-16 wk and disappeared by 19 wk. Biopsy samples revealed that adipocyte size of fat-fed obese rats was already close to maximal at 10 wk (1.12 micrograms lipid), while that of chow-fed obese rats only approached maximal at 20 wk (0.81 microgram lipid). At these time points, lipoprotein lipase activity paralleled adipocyte size. These data indicate that the duration of the growing obese rat's hyperphagia coincides with adipocyte filling and suggest the existence of feeding stimulatory and inhibitory signals from adipose tissue.

Plaadid / Mart Normet

Index Scriptorium Estoniae

Normet, Mart, 1979-

2005-01-01

Uute heliplaatide Depeche Mode "Playing The Angel", King, B. B. "80", Ray Charles"Genius & Friends", /Queen, PaulRodgers "Return Of The Champions", Sugababes "Taller in More Ways", Kelly Clarkson ""Breakaway, Mike Oldfield "Light and Shade"

Yield Interactions of Wheat Genotypes to Dates of Seeding in Eastern Mid Hills of Nepal

Directory of Open Access Journals (Sweden)

Rudra Bhattarai

2015-12-01

Full Text Available Wheat (Triticum aestivum L. is one of the major cereal crops and staple food sources in Nepal. Wheat varieties being popular in mid hill regions are still in the early stages of adoption. Identification of appropriate date of seeding plays important role in enhancing the adoption rate ensuring the sustainable production. Therefore, three dates viz 15th November, 1st and 15th December for seeding and twenty eight wheat genotypes were evaluated in a split plot design with two replications for two consecutive seasons in 2011/12 and 2012/13 at an altitude of 2200 masl of eastern Nepal. The results showed genetic differences and interaction effect of genotypes with the dates of sowing on grain yield, panicle length and effective tillers per square meter. The wheat sown on 1st December showed the highest yield as compared to other sown dates. Similarly, WK1907, WK1911, WK1803, WK1915, WK1909, WK1714 and WK1803 produced highest yield among the tested genotypes with retaining maximum number of effective tillers and posed suitable maturity across all sowing date.

Weaning age affects growth, feed intake, gastrointestinal development, and behavior in Holstein calves fed an elevated plane of nutrition during the preweaning stage.

Science.gov (United States)

Eckert, E; Brown, H E; Leslie, K E; DeVries, T J; Steele, M A

2015-09-01

Recent research has revealed potential advantages of feeding an elevated plane of nutrition to calves during the preweaning period. However, calves fed more nutrients preweaning may be more susceptible to depressed growth and weaning stress during the transition from liquid to solid feed. The objective of this study was to investigate the relationship between the age of weaning and feed intake, and its influence on growth, gastrointestinal development, and behavioral indicators in dairy calves fed an elevated plane of nutrition during the preweaning period. To meet this objective, 20 female Holstein calves were randomly assigned at birth to be weaned at 6 or 8 wk. Milk replacer (mixed at 150 g/L) was offered at 1.2 kg/calf per day in 2 meals until a 1-wk step-down, when meals were reduced by 50% 1 wk before weaning. Daily starter, chopped oat straw, water intake, and weekly body weights were measured until d 70 of life. To assess digestive tract development, rumen fluid, fecal, and blood samples were taken before and after weaning (d 35, 49, and 63) and analyzed for ruminal short-chain fatty acids, blood β-hydroxybutyrate, and fecal starch, respectively. Behavioral indicators of weaning stress, including vocalizing and non-nutritive oral behavior, were measured by visual observation for 1 h, 3 times per week, before the second feeding of the day during the period from 2 wk before weaning to 2 wk after weaning. The calves weaned at 8 wk compared with 6 wk had higher average daily gain for the week preweaning (0.79±0.09 vs. 0.34±0.10 kg/d) and postweaning (1.05±0.09 vs. 0.35±0.11 kg/d), and were heavier at d 70 (99.9±1.81 vs. 91.0±2.26 kg). From 5 to 8 wk of age, starter and water intakes were lower in calves weaned at 8 wk of age. However, overall starter intake did not differ during the last week of the experiment. Furthermore, calves weaned at 8 wk compared with 6 wk had higher starter intake for 1 wk preweaning (1.36±0.13 vs. 0.40±0.08 kg/d) and

The idea factory: Bell Labs and the great age of American innovation

National Research Council Canada - National Science Library

Gertner, Jon

2012-01-01

.... And at its heart this is a story about a small group of brilliant and eccentric men including Mervin Kelly, Bill Shockley, Claude Shannon, John Pierce, and Bill Baker who spent their careers at Bell Labs...

Research

African Journals Online (AJOL)

ebutamanya

2016-02-18

, Paul Kelly1,4. 1Tropical Gastroenterology & Nutrition Group, University of Zambia ..... 22. Valeska Portela Lima, Marcos Antonio Pereira de Lima, Angela. Rosa André, Márcia Valéria Pitombeira Ferreira, Marcos Aurélio.

ÿþE k a m e n S e p t 2 0 1 0 4 A j o l . c d r

African Journals Online (AJOL)

ÿþU s e r

1890), Kelly. (1893),Latzko (1942) .... General Five point occupational classification modified to suit our environment. A total of 4520 deliveries ... Vulval dermatitis/Vaginal Stenosis. 6. (16.2). Abdominalpains/swelling. 3. (8.1). Others. 4. (10.8).

Operational research(ers) in development: Growing a new ...

African Journals Online (AJOL)

working with individual stakeholders to capture their individual cognitive ..... [14] Kelly GA, 1955, The psychology of personal constructs, Norton, New York (NY). ... [26] Scavarda A, Bouzdine-Chameeva T, Goldstein S, Hays J & Hill A, 2006, ...

75 FR 44050 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2010-07-27

..., Mitchell L. Carmen, Christopher R. Cone, Walter O. Connelly, Stephen B. Copeland, Armando P. D'Angeli..., Andrew C. Kelly, Jason W. King, James T. Leek, Billy J. Lewis, Velmer L. McClelland, Larry McCoy, Sr...

77 FR 46283 - Amendment of Class E Airspace; Battle Creek, MI

Science.gov (United States)

2012-08-03

...) Standard Instrument Approach Procedures at W.K. Kellogg Airport. The airport's geographic coordinates also... controlled airspace at W.K. Kellogg Airport (77 FR 29918) Docket No. FAA-2011-1110. Interested parties were... instrument approach procedures at W.K. Kellogg Airport, Battle Creek, MI. This action is necessary for the...

Effect of feed presentation on feeding patterns of dairy calves.

Science.gov (United States)

Miller-Cushon, E K; Bergeron, R; Leslie, K E; Mason, G J; DeVries, T J

2013-01-01

The objectives of this study were to determine the effect of feed presentation on meal frequency and duration, as well as diurnal feeding patterns of dairy calves, and to assess any longer-term differences in feeding patterns resulting from previous experience. Twenty Holstein bull calves were exposed from wk 1 to 8 of life to 1 of 2 feed presentation treatments: concentrate and chopped grass hay (Feed was provided ad libitum. Calves received 8L/d of milk replacer (1.2 kg of dry matter), with the amount progressively reduced after 5 wk to facilitate weaning by the end of wk 7. At the beginning of wk 9, all calves received the MIX diet and remained on trial for an additional 3 wk. Feeding behavior was recorded from video for 4d during wk 6, 8, 9, and 11. In wk 6, calves fed MIX spent more time feeding than calves fed COM (56.7 vs. 46.8 min/d). In wk 8, calves fed MIX spent more time feeding (174.0 vs. 139.1 min/d) and had a lower rate of intake (11.5 vs. 14.7 g/min) compared with calves fed COM. Meal frequency was similar between treatments (12.2 meals/d). Diurnal feeding patterns in wk 8 were also affected by feed presentation, with calves fed MIX spending less time feeding at time of feed delivery and more time feeding throughout the rest of the daylight hours than calves fed COM. Diurnal feeding patterns of hay and concentrate in wk 8 differed for calves fed COM, with more time spent consuming hay at time of feed delivery and less time spent consuming hay throughout the rest of the day. Once calves previously fed COM were transitioned to the MIX diet in wk 9, meal frequency, meal duration, and diurnal feeding patterns were similar between treatments: both treatments spent similar amounts of time feeding (173.9 min/d) and had similar peaks in feeding activity at time of feed delivery, sunrise, and sunset. Provision of hay and concentrate to young calves as a mixed ration, compared with separate components, increases time spent feeding and results in more evenly

75 FR 60861 - Qualification of Drivers; Exemption Renewals; Vision

Science.gov (United States)

2010-10-01

.... Connelly, Stephen B. Copeland, Armando P. D'Angeli, Donald R. Davis, Ivory Davis, Louis A. DiPasqua, Jr..., Jesse P. Jamison, James A. Jones, Ronnie M. Jones, Andrew C. Kelly, Jason W. King, James T. Leek, Billy...

75 FR 11917 - Chrysler LLC, Technology Center, Including On-Site Leased Workers from Aerotek, Ajilon, Altair...

Science.gov (United States)

2010-03-12

... Services, Magnasteyr, Meda Technical Services, Modern Professional Services, MSX International, Optimal, Q..., Meda Technical Services, Modern Professional Services, MSX International, Optical Q Quest Corp... Consultants, Kelly Services, Meda Technical Services, Modern Professional Services, MSX International, O/E...

Risk factors that affect reproductive target achievement in fertile dairy cows.

Science.gov (United States)

Aungier, S P M; Roche, J F; Diskin, M G; Crowe, M A

2014-01-01

The aims of the present study were to investigate (1) the risk factors that influence the achievement of reproductive targets postpartum (pp) and (2) the key factors that influence pregnancy rate following first artificial insemination (AI) in dairy cows. Ninety-eight Holstein-Friesian pp cows were blood sampled from wk 1 to 4 pp for hematology and biochemistry. Reproductive tract health was assessed weekly by ultrasonography and vaginal mucus scoring. Body condition score (BCS), lameness score, and milk yield were assessed every 2 wk. Milk samples for progesterone assay were collected twice weekly and on d 4, 5, and 7 after AI. Risk factors associated with achieving reproductive targets depended on (1) increased metabolic activity of the liver (increased glutamate dehydrogenase at calving and increased γ-glutamyl transpeptidase in wk 4), (2) a competent immune system (increased neutrophils in wk 1; decreased α1-acid glycoprotein in wk 1, 2, and 3), (3) an endocrine system that was capable of responding by producing sufficient triiodothyronine in wk 2 and increased insulin-like growth factor I in wk 3 and 4, (4) a lower negative energy balance status (decreased nonesterified fatty acid concentration in wk 1; decreased β-hydroxybutyrate concentration in wk 2; BCS loss between calving and d 28 pp mucus discharge at first ovulation and at d 45 pp; resumed ovarian cyclicity by the end of the voluntary waiting period (≥ d 35 pp)], and (6) adequate diet (to ensure increased glutathione peroxidase in wk 2 and 3 and increased magnesium in wk 4). Risk factors that increased the odds of a successful first AI were previous ovulation(s) (odds ratio=3.17 per ovulation), BCS >2.5 at AI (odds ratio=3.01), and clear vaginal mucus (score=0) compared with purulent mucus (score >0) 4 d after first AI (odds ratio=2.99). In conclusion, this study identified key risk factors in the early pp period that give a higher probability of cows achieving their reproductive targets and of

Commercial Hy-Line W-36 pullet and laying hen venous blood gas and chemistry profiles utilizing the portable i-STAT?1 analyzer

OpenAIRE

Schaal, T. P.; Arango, J.; Wolc, A.; Brady, J. V.; Fulton, J. E.; Rubinoff, I.; Ehr, I. J.; Persia, M. E.; O'Sullivan, N. P.

2015-01-01

Venous blood gas and chemistry reference ranges were determined for commercial Hy-Line W-36 pullets and laying hens utilizing the portable i-STAT?1 analyzer and CG8+ cartridges. A total of 632 samples were analyzed from birds between 4 and 110 wk of age. Reference ranges were established for pullets (4 to 15 wk), first cycle laying hens (20 to 68 wk), and second cycle (post molt) laying hens (70 to 110 wk) for the following traits: sodium (Na mmol/L), potassium (K mmol/L), ionized calcium (iC...

Determinan Nilai Pelanggan dan Implikasinya pada Dependensi Pelanggan Bengkel Suv Premium

Directory of Open Access Journals (Sweden)

Aditya Wardhana

2015-06-01

Full Text Available he implementation of ASEAN Economic Community (AEC for Indonesia making its big market more capitalized and and grow rapidly. The Indonesian automotive industrial market has become ASEAN’s biggest auto market. Automotive products in Indonesia is divided into two is a variant of commercial vehicles and passenger vehicle. Passenger vehicle is divided into three types namely: sedan, multi purpose vehicle (MPV, sport utility vehicle (SUV. The aim of this study is to investigate the determinants of customer value such as service quality and customer relationship management (CRM and its implications on customer dependence. This research using a method of survey with a number of population 63.015 customers and 400 respondents as customers at premium SUV authorized service station in urban areas in West Java with using slovin formula. Analysis of data using path analysis. The result of this research concluded that the service quality and customer relationship management influenced partially significant on the perceived value of customers of car workshop premium SUV.

PENGARUH EFIKASI DIRI, LINGKUNGAN SOSIAL, AKSES KEPADA MODAL, DAN KEPEMILIKAN JARINGAN SOSIAL TERHADAP SIKAP KEWIRAUSAHAAN MAHASISWA PROGRAM STUDI PENDIDIKAN AKUNTANSI ANGKATAN 2013 UNIVERSITAS NEGERI SEMARANG

Directory of Open Access Journals (Sweden)

Retno Ariyani Puji Lestari

2017-10-01

Full Text Available This study aims to find out the influence of self efficacy, social environment, access to capital, and ownership of social networks on student entrepreneurship attitude of Accounting Education Program year 2013 UNNES either simultaneously or partially. The population in this study were students of Accounting Education class of 2013 amounting to 190 students and 129 students sample after treatment with the standard formula Slovin error of 5% then using Random Propotional Sampling as the sampling technique. This study used a questionnaire as a data collection tool. Data were analyzed using descriptive statistical analysis and regression analysis. The results showed that self-efficacy, social environment, access to capital, and the ownership of social network influence simultaneously to accounting education student entrepreneurship attitude (70%. Partially self efficacy affected student entrepreneurship attitude (44,09%, social environment does not affected students entrepreneurship attitude (0,19%, access to capital does not affected student entrepreneurship attitude (0,05%, and ownership of social networks affected student entrepreneurship attitude (13,76%.

Peran Sistem Akuntansi Instansi Berbasis Akrual dalam Meningkatkan Kualitas Laporan Keuangan

Directory of Open Access Journals (Sweden)

Ida Najati

2017-02-01

Full Text Available The study objectives are to empirically examine the influence of usage of SAIBA as relationship between accrual accounting implementation and quality of Ministry/Board financial accounting report (LKKL. The research population are 464 SAIBA operators of KPPN Makassar I and II stakeholders. Samples quantity which determined by Slovin technique and cluster sampling are 82 respondents, consist of 33 respondents on KPPN Makassar I and 49 respondents on KPPN Makassar II. Data analysis tool used is PLS with second order confirmatory factor analysis. The finding shows that accrual accounting implementation has a significant effect on usage of SAIBA and the usage of SAIBA has a significant effect to quality of Ministry/Board financial accounting report (LKKL. The other finding indicated that accrual accounting implementation has significant effect on quality of Ministry/Board financial accounting report (LKKL. The maximum implementor use SAIBA in the preparation of accrual-based financial accounting report, the more it will improve the quality of Ministry/Board financial accounting report (LKKL.

Gaya Hidup dan Hipertensi Pada Lanjut Usia di Kecamatan Kasihan Bantul Yogyakarta

Directory of Open Access Journals (Sweden)

Edi Sampurno Ridwan

2016-03-01

Full Text Available Life style plays important role toward emerging chronic diseases including hypertension. This is an observationanalytical research using cross-sectional design. It was 100 respondents in the research obtained using Slovin formula from 9887 population. Stratified random sampling and simple random sampling were assigned to select sample. Variables were measured with FFQ (food frequency questionnaire, International Physical Activity Questionnaire, and Smoking Questioner. Data was analyzed using Chi-Square and the result was junk food consumption leading to 4 times risk for hypertension (OR, 4,083. In addition, sedentary behavior (p 0.004 and smoking (p 0.001 were significant factors to lead hypertension for older people. Conclusion, junk food, sedentary behavior, and smoking habits can be the risk factors of hypertension. Thus, it is imperative to develop health promotion program focusing on the changing life style for aged group.

Characteristics and Generation of Household Hazardous Waste (HHW in Semarang City Indonesia

Directory of Open Access Journals (Sweden)

Fikri Elanda

2018-01-01

Full Text Available Most of Household Hazardous Waste (HHW is currently mixed with domestics waste. So that, it can impact human health and environmental quality. One important aspect in the management strategy is to determine the quantity generated and characteristics of HHW. The method used to determine the characteristics HHW refers to SNI 19-2454-2002, while the HHW generation refers to the SNI 19-3694-1994 calculated based on weight and volume. Research was conducted in four districts of Semarang. The samples used in this study were 400 families calculated based on the proportion of Slovin Formula. The characteristic of HHW in Semarang City is mainly infectious (79%, then poisonous (13%, combustible (6% and corrosive materials (2%. The quantity HHW generated is 0.01 kg/person/day equivalent with 5.1% of municipal solid waste (MSW in Semarang (linear equations : y=1,278x+82,00 (volume, y=0,216x+13,89 (weight.

EVALUASI PENGEMBANGAN DESA BUDAYA KERTALANGU DENPASAR SEBAGAI DAYA TARIK WISATA

Directory of Open Access Journals (Sweden)

I Made Agus Asta Panca

2016-01-01

Full Text Available The Kertalangu Cultural Village, located just north of Sanur beach, was established in 2007 and meant to be an alternative tourist attraction in Denpasar. Initially, this cultural village had developed as planned, but later on it faced a phase of decline. This article evaluates the  implementation of Kertalangu Cultural Village development program seen from the aspect of context, input, process and product. Data were collected by interviewing and distributing questionnaires. The total number of respondents was 97, determined using the Slovin formula, with the disproportionate stratified random sampling technique. Data were analyzed by Evaluation Theory, Theory of Sustainable Tourism Development and Tourism Regional Development Theory. The results show that the implementation of Kertalangu Cultural Village development programs is still not running optimally. The constraints that faced are the management is not optimal, the limited budget allocated to the development of tourism potential and the lack of good coordination between the manager and the manager at the Kesiman Kertalangu Village.

Characteristics and Generation of Household Hazardous Waste (HHW) in Semarang City Indonesia

Science.gov (United States)

Fikri, Elanda; Purwanto; Sunoko, Henna Rya

2018-02-01

Most of Household Hazardous Waste (HHW) is currently mixed with domestics waste. So that, it can impact human health and environmental quality. One important aspect in the management strategy is to determine the quantity generated and characteristics of HHW. The method used to determine the characteristics HHW refers to SNI 19-2454-2002, while the HHW generation refers to the SNI 19-3694-1994 calculated based on weight and volume. Research was conducted in four districts of Semarang. The samples used in this study were 400 families calculated based on the proportion of Slovin Formula. The characteristic of HHW in Semarang City is mainly infectious (79%), then poisonous (13%), combustible (6%) and corrosive materials (2%). The quantity HHW generated is 0.01 kg/person/day equivalent with 5.1% of municipal solid waste (MSW) in Semarang (linear equations : y=1,278x+82,00 (volume), y=0,216x+13,89 (weight).

Viral Marketing Determinants of Top Online Shop Brands in Indonesia

Directory of Open Access Journals (Sweden)

Aditya Wardhana

2016-06-01

Full Text Available The existence of the internet starts to shifting the purchase as a conventional to online. One of marketing strategies used by online store is viral marketing.The purpose of this study is to find determinant that forms viral marketing based on perceived customers in top brand online store such as lazada.com, olx.com, tokopedia.com, zalora.com, blibli.com, and bhinneka.com. The Research methodology used is the quantitative method with descriptive analysis using factor analysis by a population as 3.271.147 people and the number of sample uses Slovin formulas with confidency level at 95 % obtained as 400 respondents. Based on the result of research, there are twelve factors formed a new factor called viral marketing online store. Based on its priority, those dimensions of viral marketing online store can be sorted as follows: customer recommendation, newsletter, linking strategies, communities, free offer, sweepstakes, list of prospective buyers, chatrooms, reference list, product texts, affiliate programs, dan search engine.

Dynamic changes of photorecrptor layer in eyes with acute central serous chorioretinopathy after laser treatment by fourier-domain optical coherence tomography

Directory of Open Access Journals (Sweden)

Li-Qin Zhou

2014-10-01

Full Text Available AIM: To dynamically observe the feeling change of the photorecrptor layer in the eyes with acute central serous chorioretinopathy(CSCRkrypton laser treatment by fourier-domain optical coherence tomography(FD-OCT, and to study their correlation with the chang of vision.METHODS: This is a retrospective case series study. The clinical diagnosis of 52 patients with monocular initial onset of central serous chorioretinopathy, krypton laser photocoagulation before treatment, after 1, 2, 4, 6, 8wk, 6mo, FD-OCT were performed to observe the morphological changes characteristic of photoreceptor layer and changes in vision. RESULTS: After 1wk treatment, all cases were improved; 2wk, 6 cases were cured; 4wk, 38 cases were cured; 6wk, 41 cases were cured; 8wk, 45 cases were cured, the OCT showed macular retinal neuroepithelial layer(RNLfrom fully absorbed; 6mo with the same 8wk. Before and after treatment in patients with best corrected visual acuity and from the height difference between the macular region of RNL was statistically significant(PPPCONCLUSION: FD-OCT can dynamicaly observed acute central serous chorioretinopathy krypton laser treatment of photoreceptor ultrastruture changes. Photoreceptor layer of complete and incomplete best corrected visual acuity difference was statistically significant(P<0.01.

Study on the mechanism of retinal ganglion cell apoptosis in early stage of diabetic rats

Directory of Open Access Journals (Sweden)

Rui-Dong Gu

2014-03-01

Full Text Available AIM: To investigate the mechanism of retinal ganglion cell apoptosis in early stage of streptozotocin(STZ-induced diabetic rats. METHODS: Sixty SD rats were randomly divided into two groups: control group(CONand diabetes mellitus group(DM. Diabetic rat model was produced by intraperitoneal injection of 1% STZ in 30 adult male SD rats. At 4, 8, 12wk,the rats were killed and eyeballs were enucleated for the HE staining, TUNEL staining, transmission electron microscopy detection respectively, and laser confocal microscope detection was used to detect the calcium ion concentration.RESULTS:At 8wk RGCs decreased gradually and appeared disordered arrangement and got worse at 12wk in DM group. In DM group, mitochondrial swelling was detected at 4wk., and became more obvious, more in number at 8wk with reduction in some cells' volume and the number of organelles decreased. In DM group, few TUNEL positive RGCs were seen at 4wk, and became more and more at 8 and 12wk. The apoptosis index was significantly higher in DM group compared with CON group in different time points(PPPCONCLUSION: The study suggested that RGCs apoptosis occurs in early stage of diabetes, the mechanism might be associated with increased intracellular calcium ion concentration.

Pathological studies on lachrymal dilated drainage tube implantation in rabbits

Directory of Open Access Journals (Sweden)

Yun Peng

2014-06-01

Full Text Available AIM: To observe the pathological changes of the lower segment of nasolacrimal duct mucosa in rabbits at different stages after retrograde lachrymal dilated drainage tube implantation. METHODS: Totally 14 New Zealand rabbits were used in the present study. One side of nasolacrimal duct was obstructed to produce an experimental model and operated the reverse implantation of nasolacrimal duct intubation. Histological changes of the lower segment of nasolacrimal duct mucosa were observed by routine light microscope at 2, 4, 6, 8, 10, 12 and 14wk after the operation. RESULTS: Compared with the control side, the group of 2 and 4wk after surgery presented the inflammatory cytokine. The group of 12wk after the operation presented isolated granuloma. Group 12 and 14wk presented scattered granuloma. The size of the granulomas was smaller and the density of epithelioid cell and fibroblast were lower in group 12wk than those in group 14wk by HE and Masson trichrome stain.CONCLUSION: Recurrent Silicone Tube is used to treat nasolacrymal duct obstruction. Nasolacrimal duct can be narrowed and blocked again by granuloma, progressive fibrosis and adhesion of surrounding tissues when tube is in the duct more than 12wk.

Disease: H00481 [KEGG MEDICUS

Lifescience Database Archive (English)

Full Text Available -1172-2-7 ... PMID:21552474 ... AUTHORS ... Garcia-Hoyos M, Auz-Alexandre CL, Almoguera B, Cantalapiedra D, Riveiro...-Alvarez R, Lopez-Martinez MA, Gimenez A, Blanco-Kelly F, Avila-Fernandez A, Trujillo-Tiebas MJ, Garcia-Sand

Pühapäev kunsti ja muusikaga / Mari Hiiemäe

Index Scriptorium Estoniae

Hiiemäe, Mari

2008-01-01

Jazzkaare 20. aprillil korraldatavast kunsti ja muusika pühapäevast Niguliste muuseumis (esineb East-West Quartet), Tallinna Kunstihoones (Estonian Guitar Octet), Rotermanni soolalaos (Raivo Tafenau ja Meelis Vindi duo) ja Kumu auditooriumis (laulja Kelli Uustani plaadiesitlus)

Pingelised suhted / Einar Ellermaa

Index Scriptorium Estoniae

Ellermaa, Einar, 1960-

2007-01-01

Ameerika teleseriaali "Vaprad ja ilusad" TV 3s näidatavate osade ja tegelaste kohta. Lisatud Brooke'i osatäitja Katherine Kelly Langi intervjuu Soap Opera Weekly'st. Sama ka Teleleht nr. 36, lk. 6-7 : ill

77 FR 46153 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2012-08-02

.... Carman (OH) Christopher R. Cone (GA) Walter O. Connelly (WA) Stephen B. Copeland (GA) Armando P. D'Angeli... (PA) Jesse P. Jamison (TN) Ronnie M. Jones (ID) Andrew C. Kelly (WV) Jason W. King (MT) James T. Leek...

Effects of Different Exercise Modes on Arterial Stiffness and Nitric Oxide Synthesis.

Science.gov (United States)

Hasegawa, Natsuki; Fujie, Shumpei; Horii, Naoki; Miyamoto-Mikami, Eri; Tsuji, Katsunori; Uchida, Masataka; Hamaoka, Takafumi; Tabata, Izumi; Iemitsu, Motoyuki

2018-06-01

Aerobic training (AT) and high-intensity intermittent training (HIIT) reduce arterial stiffness, whereas resistance training (RT) induces deterioration of or no change in arterial stiffness. However, the molecular mechanism of these effects of different exercise modes remains unclear. This study aimed to clarify the difference of different exercise effects on endothelial nitric oxide synthase (eNOS) signaling pathway and arterial stiffness in rats and humans. In the animal study, forty 10-wk-old male Sprague-Dawley rats were randomly divided into four groups: sedentary control (CON), AT (treadmill running, 60 min at 30 m·min, 5 d·wk for 8 wk), RT (ladder climbing, 8-10 sets per day, 3 d·wk for 8 wk), and HIIT (14 repeats of 20-s swimming session with 10-s pause between sessions, 4 d·wk for 6 wk from 12-wk-old) groups (n = 10 in each group). In the human study, we confirmed the effects of 6-wk HIIT and 8-wk AT interventions on central arterial stiffness and plasma nitrite/nitrate level in untrained healthy young men in randomized controlled trial (HIIT, AT, and CON; n = 7 in each group). In the animal study, the effect on aortic pulse wave velocity (PWV), as an index of central arterial stiffness, after HIIT was the same as the decrease in aortic PWV and increase in arterial eNOS/Akt phosphorylation after AT, which was not changed by RT. A negative correlation between aortic PWV and eNOS phosphorylation was observed (r = -0.38, P HIIT- and AT-induced changes in carotid-femoral PWV (HIIT -115.3 ± 63.4 and AT -157.7 ± 45.7 vs CON 71.3 ± 61.1 m·s, each P HIIT may reduce central arterial stiffness via the increase in aortic nitric oxide bioavailability despite it being done in a short time and short term and has the same effects as AT.

Effects of paternal obesity on growth and adiposity of male rat offspring.

Science.gov (United States)

Lecomte, Virginie; Maloney, Christopher A; Wang, Kristy W; Morris, Margaret J

2017-02-01

Emerging evidence suggests that paternal obesity plays an important role in offspring health. Our previous work using a rodent model of diet-induced paternal obesity showed that female offspring from high-fat diet (HFD)-fed fathers develop glucose intolerance due to impairment of pancreatic insulin secretion. Here, we focused on the health outcomes of male offspring from HFD-fed fathers. Male Sprague-Dawley rats (3 wk old) were fed control (CD-F0) or HFD (HFD-F0) for 12 wk before mating with control-fed females. Male offspring were fed control diets for up to 8 wk or 6 mo. Although male offspring from HFD-F0 did not develop any obvious glucose metabolism defects in this study, surprisingly, a growth deficit phenotype was observed from birth to 6 mo of age. Male offspring from HFD-F0 had reduced birth weight compared with CD-F0, followed by reduced postweaning growth from 9 wk of age. This resulted in 10% reduction in body weight at 6 mo with significantly smaller fat pads and skeletal muscles. Reduced circulating levels of growth hormone (GH) and IGF-I were detected at 8 wk and 6 mo, respectively. Expression of adipogenesis markers was decreased in adipose tissue of HFD-F0 offspring at 8 wk and 6 mo, and expression of growth markers was decreased in muscle of HFD-F0 offspring at 8 wk. We propose that the reduced GH secretion at 8 wk of age altered the growth of male offspring from HFD-F0, resulting in smaller animals from 9 wk to 6 mo of age. Furthermore, increased muscle triglyceride content and expression of lipogenic genes were observed in HFD-F0 offspring, potentially increasing their metabolic risk. Copyright © 2017 the American Physiological Society.

Efficacy of intravitreal ranibizumab injection combined with macular grid photocoagulation for diabetic macular edema

Directory of Open Access Journals (Sweden)

Hu-Lin Jiang

2014-07-01

Full Text Available AIM:To evaluate the clinical efficacy of intravitreal injection of ranibizumab combined with macular grid photocoagulation for diabetic macular edema(DME.METHODS:Totally 60 eyes(60 patientswith DME were randomly divided into 2 groups: 30 eyes of simple injection group underwent intravitreal injection of ranibizumab, and 30 eyes of combined treatment group underwent intravitreal injection of ranibizumab and macular grid photocoagulation 1wk later. The best corrected visual acuity(BCVA, central macular thickness(CMTmeasured by optical coherence tomography(OCTand postoperative complications were observed.RESULTS:In simple injection group, the BCVA after operation were separately 0.390±0.075(4wk, 0.367±0.088(8wkand 0.319±0.064(12wk,the CMT after operation were separately 221.63±112.34μm(4wk, 337.73±99.56μm(8wkand 432.92±100.46μm(12wk, which were much better than pre-operation. But during follow-up, the BCVA presented down trend and the CMT was on the rise slowly. In combined treatment group, the BCVA after operation were separately 0.385±0.036(4wk, 0.382±0.079(8wkand 0.377±0.097(12wk,the CMT after operation were separately 249.77±106.55μm(4wk, 270.40±92.88μm(8wkand 275.84±97.34μm(12wk, which were satisfactory and steady during follow-up, better than simple injection group(PCONCLUSION:Intravitreal injection of ranibizumab can effectively improve visual acuity and decrease central foveal thickness for patients with DME, combining with macular grid photocoagulation can ensure therapeutic effects steady and permanent.

AMPK agonist AICAR delays the initial decline in lifetime-apex V̇o2 peak, while voluntary wheel running fails to delay its initial decline in female rats.

Science.gov (United States)

Toedebusch, Ryan G; Ruegsegger, Gregory N; Braselton, Joshua F; Heese, Alexander J; Hofheins, John C; Childs, Tom E; Thyfault, John P; Booth, Frank W

2016-02-01

There has never been an outcome measure for human health more important than peak oxygen consumption (V̇o2 peak), yet little is known regarding the molecular triggers for its lifetime decline with aging. We examined the ability of physical activity or 5 wk of 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) administration to delay the initial aging-induced decline in lifetime-apex V̇o2 peak and potential underlying molecular mechanisms. Experiment 1 consisted of female rats with (RUN) and without (NO RUN) running wheels, while experiment 2 consisted of female nonrunning rats getting the AMPK agonist AICAR (0.5 mg/g/day) subcutaneously for 5 wk beginning at 17 wk of age. All rats underwent frequent, weekly or biweekly V̇o2 peak tests beginning at 10 wk of age. In experiment 1, lifetime-apex V̇o2 peak occurred at 19 wk of age in both RUN and NO RUN and decreased thereafter. V̇o2 peak measured across experiment 1 was ∼25% higher in RUN than in NO RUN. In experiment 2, AICAR delayed the chronological age observed in experiment 1 by 1 wk, from 19 wk to 20 wk of age. RUN and NO RUN showed different skeletal muscle transcriptomic profiles both pre- and postapex. Additionally, growth and development pathways are differentially regulated between RUN and NO RUN. Angiomotin mRNA was downregulated postapex in RUN and NO RUN. Furthermore, strong significant correlations to V̇o2 peak and trends for decreased protein concentration supports angiomotin's potential importance in our model. Contrary to our primary hypothesis, wheel running was not sufficient to delay the chronological age of lifetime-apex V̇o2 peak decline, whereas AICAR delayed it 1 wk. Copyright © 2016 the American Physiological Society.

The Effect of Double Buffer Management in Packet Analysis of ...

African Journals Online (AJOL)

Software Development ... Kelly's Scalable TCP on real networks with a set of systematic tests using ... which is widely used for Wireless LANs today, ·a 'Single queue is used in best-effort ...... support and resource allocation with timely support.

75 FR 77666 - General Motors Company, Formerly Known as General Motors Corporation, Technical Center, Including...

Science.gov (United States)

2010-12-13

...., Global Technology Associates Limited, G-Tech Professional Staffing, Inc., Jefferson Wells, Kelly Services... Enterprise Services, Engineering Labs, Inc., Global Technology Associates Limited, G-Tech Professional... company reports that workers leased from Modern Engineering/ Professional Services were employed on-site...

30. IX kuni 31. XII 2000 toimus Makedoonia Vabariigis...

Index Scriptorium Estoniae

2001-01-01

III rahvusvaheline graafikatriennaal "Bitola 2000" teemadel "2000 aastat kristlust" ja "Metamorfoos". Eestist osalesid Peeter Allik, Sirje Eelma, Kelli Kagovere, Avo Keerend, Ilmar Kruusamäe, Raul Meel, Benjamin Vasserman. Peapreemia - poola graafiku Mira Boczniowiczi töö "Empire Sign".

Intellektuaalne emotsionaalsus / Reet Varblane

Index Scriptorium Estoniae

Varblane, Reet, 1952-

2010-01-01

Mary Kelly näitus "Neli tööd dialoogis" Stockholmis Moderna Museetis 23. jaanuarini 2011. Eksponeeritud installatsioonid "Post-Partum'i dokument" (1973-1079), "Kastriot Rexhepi ballaad" (2001), "Mitmekorruseline maja" (2007) ja "Habitus" (2010) ning fotoseeria "Primapara" (1974)

76 FR 44948 - Status Report of Water Service, Repayment, and Other Water-Related Contract Actions

Science.gov (United States)

2011-07-27

... DEPARTMENT OF THE INTERIOR Bureau of Reclamation Status Report of Water Service, Repayment, and Other Water- Related Contract Actions AGENCY: Bureau of Reclamation, Interior. ACTION: Notice. SUMMARY... SUPPLEMENTARY INFORMATION section. FOR FURTHER INFORMATION CONTACT: Michelle Kelly, Water and Environmental...

Elevated corticotropin releasing hormone (CRH) during pregnancy and risk of postpartum depression (PPD).

Science.gov (United States)

Meltzer-Brody, Samantha; Stuebe, Alison; Dole, Nancy; Savitz, David; Rubinow, David; Thorp, John

2011-01-01

Perinatal depression has a prevalence of 10% with devastating consequences for mother and baby. The prospective identification of those at risk for postpartum (PPD) or prenatal (PND) depression has led to biomarker searches in pregnancy. There are conflicting reports of associations between midpregnancy placental CRH (pCRH) and PPD or PND. The objective of the study was to quantify the association of maternal pCRH with PPD and PND. This was a prospective cohort study (the Pregnancy, Infection, and Nutrition Study). The study was conducted at a prenatal clinics at the University of North Carolina at Chapel Hill. Patients included 1230 pregnant women. The relationship between pCRH at less than 20 wk and 24-29 wk and maternal depression assessed in pregnancy [Center for Epidemiologic Studies Depression Scale (CES-D)] and postpartum (12 wk and 1 yr) with the Edinburgh Postnatal Depression Scale (EPDS). At 24-29 wk, 24.8% of women had CES-D score of 17 or greater, and 9.7% had a CES-D score of 25 or greater. At 12 wk postpartum, 18.2% of women had an EPDS score of 10 or greater and 7.6% had an EPDS score of 13 or greater. CRH measures at less than 20 wk and 24-29 wk were inversely correlated with a CES-D score at 24-29 wk (n = 1080, P PPD (covariate-adjusted odds ratio per sd 0.99, 95% confidence interval 0.69-1.42). Higher midpregnancy pCRH was not associated with an increased risk of PND or PPD.

Changes in the content of edible and non-edible components and distribution of tissue components in cockerels and capons

Directory of Open Access Journals (Sweden)

Magdalena Zawacka

2018-04-01

Full Text Available The aim of this study was to determine the effects of castration and age on the content of edible and non-edible components, and the distribution of tissue components in the carcasses of cockerels and capons. The study was conducted on 200 birds (Green-legged Partridge, divided into two sex categories (with 5 replications per group and 20 birds per replication, raised to 28 wk of age. At 8 wk of age, 100 birds were surgically castrated and afterwards at 12 wk of age and at four-wk intervals, 10 intact cockerels and 10 capons were selected randomly and slaughtered. Cockerels, compared with capons, were characterized by a higher proportion of edible components at 24 and 28 wk of age, and a more desirable carcass tissue composition due to a higher content of lean meat in total body weight (BW. Capons had higher abdominal fat content than cockerels, which resulted in a higher percentage of non-edible components in their BW at 24 and 28 wk of age. Differences in the distribution of lean meat in the carcass were noted from 20 wk of age in both castrated and intact birds. The content of breast muscles increased in capons, and the content of leg muscles (thigh and drumstick increased in cockerels. The results of this study indicate that in view of the optimal lean meat content of the carcass and the optimal distribution of major tissue components, Green-legged Partridge capons should be fattened for a maximum period of 24 wk.

Changes in the content of edible and non-edible components and distribution of tissue components in cockerels and capons

International Nuclear Information System (INIS)

Zawacka, M.; Gesek, M.; Michalik, D.; Murawska, D.

2018-01-01

The aim of this study was to determine the effects of castration and age on the content of edible and non-edible components, and the distribution of tissue components in the carcasses of cockerels and capons. The study was conducted on 200 birds (Green-legged Partridge), divided into two sex categories (with 5 replications per group and 20 birds per replication), raised to 28 wk of age. At 8 wk of age, 100 birds were surgically castrated and afterwards at 12 wk of age and at four-wk intervals, 10 intact cockerels and 10 capons were selected randomly and slaughtered. Cockerels, compared with capons, were characterized by a higher proportion of edible components at 24 and 28 wk of age, and a more desirable carcass tissue composition due to a higher content of lean meat in total body weight (BW). Capons had higher abdominal fat content than cockerels, which resulted in a higher percentage of non-edible components in their BW at 24 and 28 wk of age. Differences in the distribution of lean meat in the carcass were noted from 20 wk of age in both castrated and intact birds. The content of breast muscles increased in capons, and the content of leg muscles (thigh and drumstick) increased in cockerels. The results of this study indicate that in view of the optimal lean meat content of the carcass and the optimal distribution of major tissue components, Green-legged Partridge capons should be fattened for a maximum period of 24 wk.

YouTube onder de loep: is er plaats voor UGC platforms in de veilige havens van de e-commerce richtlijn?

NARCIS (Netherlands)

Breemen, V.; Breemen, K.

2013-01-01

In ‘YouTube onder de loep’ onderzoeken Vicky Breemen en Kelly Breemen de positie van platformbeheerders onder de E-Commerce Richtlijn met betrekking tot auteursrechtschendende user-generated content. In het onderzoek, dat een functiegerichte benadering voorstelt, wordt het immuniteitsregime

Discussing the transformative functioning of occupation

DEFF Research Database (Denmark)

Josephsson, Staffan; Madsen, Jacob Østergaard; Aldrich,, Rebecca M.

), Narrative - in – action (Ricoeur, Bruner and Mattingly) Personal construct theory (eg Kelly, Sarbin, Little and Baumeister) Intrinsic motivation theory (e g,White, Bandura, Deci & Ryan, etc), and Developmental theory (Piaget, Erikson, Baltes, etc), Importance to occupational science: Occupation is used...

OYSTER POPULATUION ESTIMATION IN SUPPORT OF THE TEN-YEAR GOAL FOR OYSTER RESOTRATION IN THE CHESAPEAKE BAY: DEVELOPING STRATEGIES FOR RESTORING AND MANAGING THE EASTERN OYSTER

Science.gov (United States)

Mann, Roger, Steve Jordan, Gary Smith, Kennedy Paynter, James Wesson, Mary Christman, Jessica Vanisko, Juliana Harding, Kelly Greenhawk and Melissa Southworth. 2003. Oyster Population Estimation in Support of the Ten-Year Goal for Oyster Restoration in the Chesapeake Bay: Develop...

Lakk-kilpkellad Eesti Rahva Muuseumis - säilitamine ja konserveerimine / Pille Vilgota

Index Scriptorium Estoniae

Vilgota, Pille

2011-01-01

Käsitletakse lakk-kilpkellade ajalugu, nende säilitamist ja konserveerimist ning see on eeltööks kellade konserveerimise metoodika väljaarendamisel. Uurimise tulemusena täpsustus eestikeelne terminoloogia, mis võimaldab kelli täpsemalt kirjeldada ja eristada

On the method of calibration of the energy dispersive EXAFS ...

Indian Academy of Sciences (India)

samples, whose absorption edge energies are well-established. .... bend the crystal to take shape of an ellipse (Lee et al 1994). ..... Kelly S D, Hesterberg D and Ravel B 2008 Methods of Soil Analysis, Part 5, Mineralogical Methods,. Chapter ...

75 FR 14606 - Medicare Program; Request for Nominations to the Advisory Panel on Ambulatory Payment...

Science.gov (United States)

2010-03-26

..., CPHQ Patrick A. Grusenmeyer, Sc.D., FACHE David Halsey, M.D. Judith T. Kelly, B.S.H.A., RHIT, RHIA, CCS....D.* Daniel Pothen, M.S., RHIA, CPHIMS, CCS, CCS-P, CHC Gregory J. Przbylski, M.D. Russ Ranallo, M.S...

77 FR 51542 - Medicare Program; Solicitation of Two Nominations to the Advisory Panel on Hospital Outpatient...

Science.gov (United States)

2012-08-24

... T. Kelly, B.S.H.A., RHIT, RHIA, CCS* Scott Manaker, M.D., Ph.D. John Marshall, CRA, RCC, RT Jim..., CHPS, CPHIMS, CCS, CCS-P, CHC Gregory J. Przbylski, M.D. Traci Rabine Marianna V. Spanki-Varelas M.D...

Poorly Responsive Celiac Disease

Science.gov (United States)

... Close Celiac Disease Understanding Celiac Disease What is Celiac Disease? Symptoms Screening and Diagnosis Treatment and Follow-Up Dermatitis ... Schuppan D, Kelly CP. Etiologies and predictors of diagnosis in nonresponsive celiac disease. Clin Gastroenterol Hepatol 2007; 5 : 445–50. Finding ...

76 FR 10395 - BreconRidge Manufacturing Solutions, Now Known as Sanmina-SCI Corporation, Division...

Science.gov (United States)

2011-02-24

... Solutions, Now Known as Sanmina-SCI Corporation, Division Optoelectronic and Microelectronic Design and Manufacturing, a Subsidiary of Sanmina-SCI Corporation, Including On- Site Leased Workers From Kelly Services... Manufacturing Solutions, now known as Sanmina-SCI Corporation, Division Optoelectronic and Microelectronic...

76 FR 81554 - Notice of Information Collection Under Emergency Review: 60-Day Notice of Proposed Information...

Science.gov (United States)

2011-12-28

... of Population, Refugees, and Migration, Office of Admissions (PRM/A) AGENCY: Department of State... Request: Emergency Review. Originating Office: Bureau of Population, Refugees, and Migration, Office of..., Refugees and Migration. Additional Information: Dated: December 21, 2011. Kelly A. Gauger, Deputy Director...

75 FR 42774 - Status Report of Water Service, Repayment, and Other Water-Related Contract Actions

Science.gov (United States)

2010-07-22

... DEPARTMENT OF THE INTERIOR Bureau of Reclamation Status Report of Water Service, Repayment, and Other Water- Related Contract Actions AGENCY: Bureau of Reclamation, Interior. ACTION: Notice. SUMMARY... region in the SUPPLEMENTARY INFORMATION section. FOR FURTHER INFORMATION CONTACT: Michelle Kelly, Water...

76 FR 73674 - Status Report of Water Service, Repayment, and Other Water-Related Contract Actions

Science.gov (United States)

2011-11-29

... DEPARTMENT OF THE INTERIOR Bureau of Reclamation Status Report of Water Service, Repayment, and Other Water- Related Contract Actions AGENCY: Bureau of Reclamation, Interior. ACTION: Notice. SUMMARY... INFORMATION CONTACT: Michelle Kelly, Water and Environmental Resources Division, Bureau of Reclamation, P.O...

Supplementing goat kids with coconut medium chain fatty acids in early life influences growth and rumen papillae development until 4 months after supplementation but effects on in vitro methane emissions and the rumen microbiota are transient.

Science.gov (United States)

Debruyne, Sieglinde; Ruiz-González, Alexis; Artiles-Ortega, Einar; Ampe, Bart; Van Den Broeck, Wim; De Keyser, Ellen; Vandaele, Leen; Goossens, Karen; Fievez, Veerle

2018-05-04

The aim of this study was to investigate the methane (CH4) reducing potential of a combination of prenatal and/or postnatal treatment with coconut oil medium chain fatty acids (CO MCFA) in goat kids. The hypothesis is that influencing rumen function during early life has more chances for success than in the adult life, related to the resilience of the mature rumen microbiota. Forty-eight pregnant does were split into two experimental groups: treated does (D+) received 40 g/d of CO MCFA in a test compound feed, while control does (D-) received a control compound feed, during the last 3 wk of gestation. Twin kids from 10 does of each group were split up into a treated (K+) and nontreated (K-) group, resulting in four experimental groups: D+K+, D+K-, D-K+, and D-K-. The K+ kids received 1.8 mL/d of CO MCFA from birth until 2-wk postweaning (11 wk). Irrespective of treatment, the experimental rearing conditions resulted in absence of rumen protozoa at all sampling times, assessed by quantitative PCR (qPCR). In vitro incubations with rumen fluid at 4 wk old showed 82% lower CH4 production of inoculum from D+K+ kids compared to D-K- kids (P = 0.01). However, this was accompanied by lower total volatile fatty acids (tVFA) production (P = 0.006) and higher hydrogen accumulation (P = 0.008). QPCR targeting the mcrA and rrs genes confirmed a lower abundance of total methanogens (P kids at 4 wk old. Methanogenic activity, as assessed by mcrA expression by RT-qPCR, was also lower in these kids. However, activity did not always reflect methanogen abundance. At 11 and 28 wk old, prenatal and postnatal effects on in vitro fermentation and rumen microbiota disappeared. Nevertheless, lower milk replacer intake in the first 4 wk resulted in reduced BW in K+ kids, persisting until 28 wk of age. Additionally, differences assigned to postnatal treatment were found in papillae density, width, and length in different areas of the rumen, recorded at 28 wk old. prenatal and postnatal

Effects of low energy helium plasma irradiation on potassium doped tungsten

Energy Technology Data Exchange (ETDEWEB)

Shu, Xiaoyan [Key Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu (China); Key Subject Laboratory of National Defense for Radioactive Waste and Environmental Security, Southwest University of Science and Technology, Mianyang (China); Huang, Bo [Key Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu (China); Liu, Dongping; Fan, Hongyu [School of Physics and Materials Engineering, Dalian Nationalities University, Dalian (China); Liu, Ning [Key Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu (China); Tang, Jun, E-mail: tangjun@scu.edu.cn [Key Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu (China)

2017-04-15

Effects of helium plasma irradiation on spark plasma sintering (SPS) W-K, pure W and traditionally sintered commercial W-K have been studied, concerning the density, grain size and potassium content as the influence factors. Pinholes are formed under 120 eV He ions at 600 °C and 1 × 10{sup 23} m{sup −2} fluence on the surface of all samples. It is found that SPS-sintered W-K shows the best irradiation resistance among the present samples, and SPS-sintered pure W exhibits higher irradiation tolerance than commercial W-K. Different He-plasma tolerance was observed among the SPS-sintered W-K samples due to varied potassium content and grain size. In addition, the microstructure evolution under helium irradiation, the growth-migration of helium bubbles and their interactions of potassium bubbles have also been discussed.

Mindfulness training attenuates the increase in salivary cortisol concentration associated with competition in highly trained wheelchair-basketball players.

Science.gov (United States)

MacDonald, Luke A; Minahan, Clare L

2018-02-01

This study determined the effect of 8 wk of mindfulness training (MT) on salivary cortisol (sCort) and rate of salivary Immunoglobulin-A (sIgA) secretion in wheelchair-basketball players during a competition period. The mindful group completed 8 weeks of MT in addition to training and competition. sCort and rate of sIgA secretion were measured at baseline, at 2-week intervals, the end and 2 weeks following the intervention. A significant time and group interaction was observed for sCort (F = 3.297, P = 0.040, ES = 0.191); sCort increased in the control group from MT-BL to MT-2wk (P = 0.001) and remained significantly elevated at MT-4wk (P = 0.013) and MT-6wk (P = 0.002). sCort decreased from MT-6wk to MT-8wk (P  0.05). Mindful group sCort increased from MT-BL to MT-2wk (P = 0.042) but decreased to concentrations no different to MT-BL for the rest of the intervention period (P > 0.05). There were no group differences in rate of sIgA secretion during the intervention (P = 0.810). It was concluded that 8 weeks of MT attenuated the increase in sCort associated with the competition period.

A longitudinal study of whole body, tissue, and cellular physiology in a mouse model of fibrosing NASH with high fidelity to the human condition.

Science.gov (United States)

Krishnan, Anuradha; Abdullah, Tasduq Sheikh; Mounajjed, Taofic; Hartono, Stella; McConico, Andrea; White, Thomas; LeBrasseur, Nathan; Lanza, Ian; Nair, Sreekumaran; Gores, Gregory; Charlton, Michael

2017-06-01

The sequence of events that lead to inflammation and fibrosing nonalcoholic steatohepatitis (NASH) is incompletely understood. Hence, we investigated the chronology of whole body, tissue, and cellular events that occur during the evolution of diet-induced NASH. Male C57Bl/6 mice were assigned to a fast-food (FF; high calorie, high cholesterol, high fructose) or standard-chow (SC) diet over a period of 36 wk. Liver histology, body composition, mitochondrial respiration, metabolic rate, gene expression, and hepatic lipid content were analyzed. Insulin resistance [homeostasis model assessment-insulin resistance (HOMA-IR)] increased 10-fold after 4 wk. Fibrosing NASH was fully established by 16 wk. Total hepatic lipids increased by 4 wk and remained two- to threefold increased throughout. Hepatic triglycerides declined from sixfold increase at 8 wk to threefold increase by 36 wk. In contrast, hepatic cholesterol levels steadily increased from baseline at 8 wk to twofold by 36 wk. The hepatic immune cell population altered over time with macrophages persisting beyond 16 wk. Mitochondrial oxygen flux rates of FF mice diet were uniformly lower with all the tested substrates (13-276 pmol·s -1 ·ml -1 per unit citrate synthase) than SC mice (17-394 pmol·s -1 ·ml -1 per unit citrate synthase) and was accompanied by decreased mitochondrial:nuclear gene copy number ratios after 4 wk. Metabolic rate was lower in FF mice. Mitochondrial glutathione was significantly decreased at 24 wk in FF mice. Expression of dismutases and catalase was also decreased in FF mice. The evolution of NASH in the FF diet-induced model is multiphasic, particularly in terms of hepatic lipid composition. Insulin resistance precedes hepatic inflammation and fibrosis. Mitochondrial dysfunction and depletion occur after the histological features of NASH are apparent. Collectively, these observations provide a unique overview of the sequence of changes that coevolve with the histological evolution of

Cross-sectional relationships of exercise and age to adiposity in60,617 male runners

Energy Technology Data Exchange (ETDEWEB)

Williams, Paul T.; Pate, Russell R.

2004-06-01

The objective of this report is to assess in men whether exercise affects the estimated age-related increase in adiposity, and contrariwise, whether age affects the estimated exercise-related decrease in adiposity. Cross-sectional analyses of 64,911 male runners who provided data on their body mass index (97.6 percent), waist (91.1 percent), hip (47.1 percent), and chest circumferences (77.9 percent). Between 18 to 55 years old, the decline in BMI with weekly distance run (slope+-SE) was significantly greater in men 25-55 years old (slope+-:-0.036+-0.001 kg/m2 per km/wk) than in younger men (-0.020+-0.002 kg/m 2 per km/wk). Declines in waist circumference with running distance were also significantly greater in older than younger men (P<10-9 for trend),i.e., the slopes decreased progressively from -0.035+-0.004 cm per km/wk in 18-25 year old men to -0.097+-0.003 cm per km/wk in 50-55 year old men. Increases in BMI with age were greater for men who ran under 16km/wk than for longer distance runners. Waist circumference increased with age at all running levels, but the increase appeared to diminish by running further (0.259+-0.015 cm per year if running<8 km/wk and 0.154+-0.003 cm per year for>16 km/wk). In men over 50 years old, BMI declined -0.038+-0.001 kg/m2 per km/wk run when adjusted for age and declined -0.054+-0.003 kg/m2 (increased 0.021+-0.007 cm) per year of age when adjusted for running distance. Their waist circumference declined-0.096+-0.002 cm per km/wk run when adjusted for age and increased 0.021+-0.007 cm per year of age when adjusted for running distance. These cross-sectional data suggest that age and vigorous exercise interact with each other in affecting mens adiposity, and support the proposition that vigorous physical activity must increase with age to prevent middle-age weight gain. We estimate that a man who ran 16 km/wk at age 25 would need to increase their weekly running distance by 65.7 km/wk by age 50 in order to maintain his same waist

Jane f. Kelly and catherine l. Ward Department of Psychology ...

African Journals Online (AJOL)

Department of Psychology, University of Cape Town, Cape Town, South Africa ... Substance abuse and criminality are critical problems in South Africa, yet ... cial behaviour can be divided into two groups ..... Primary Prevention, 23, 483-514.

77 FR 19719 - Whirlpool Corporation Including On-Site Leased Workers From Career Solutions TEC Staffing, IBM...

Science.gov (United States)

2012-04-02

... Logistics, Eurest, Canteen, Kelly Services, Inc., Prodriver, Arkansas Warehouse, Inc., Andrews International... information shows that workers leased from Andrews International employed on-site at the Fort Smith, Arkansas...) tax account under the name U.S. Security. Accordingly, the Department is amending this certification...

Economic values for dairy production traits under different milk ...

African Journals Online (AJOL)

Cuthbert

A well-defined breeding objective forms the basis of a sound breeding programme. .... (ZAR per unit) by breed under different milk payment systems. Milk Buyer. Breed. Trait. A. B. C .... Veerkamp, R.F., Dillon, P., Kelly, A.R. & Groen, A.F., 2002.

Analysis of Whole-Genome Data in a Public Health Lab

Centers for Disease Control (CDC) Podcasts

2017-10-17

Dr. Kelly Oakeson, a bioinformatics and genomics research analyst with the Utah Department of Health, discusses bioinformatics and genomics research.  Created: 10/17/2017 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 10/17/2017.

In Praise of Progress

Science.gov (United States)

... singer Randy Owen, formerly lead singer of the band Alabama, (with his wife Kelly). Photo courtesy of NIH NIH Director Elias Zerhouni, M.D., comments at the awards dinner focused on the vital role medical research plays in improving health care for all ...

Kaupuni Village: A Closer Look at the First Net-Zero Energy Affordable Housing Community in Hawai'i (Brochure)

Energy Technology Data Exchange (ETDEWEB)

2012-05-01

This is the first of four Hawaii Clean Energy Initiative community brochures focused on HCEI success stories. This brochure focuses on the first LEED Platinum net-zero energy affordable housing community in Hawaii. Our lead NREL contact for HCEI is Ken Kelly.

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African Journals Online (AJOL)

Adams Chaskda

Lal and Stewart 1990;. Van der Warf, and Petit, 2002; Kyba et al., 2014). Also, to ..... Farris Z.J.; Golden, C.D.; Karpanty, S.; Murphy,. A.; Stauffer, D.; Ratelolahy, F. Andrianjakarivelo, V.; Holmes, C.M. and. Kelly M.J. (2015). Hunting, Exotic.

78 FR 51727 - Announcement of the Second 2015 Dietary Guidelines Advisory Committee Meeting and Invitation for...

Science.gov (United States)

2013-08-21

... current scientific knowledge in the field of human nutrition and chronic disease. Appointed Committee.... Department of Agriculture, Food, Nutrition and Consumer Services and Research, Education, and Economics... DFO, 2015 DGAC, Kellie (O'Connell) Casavale, Ph.D., R.D., Nutrition Advisor; Office of Disease...

Browse Title Index

African Journals Online (AJOL)

Items 501 - 550 of 3286 ... C Opoku-Okrah, BKS Acquah, EE Dogbe ... Nancy Weathers, Jenna Ladd, Iretiola Fajolu, Christopher Esezobor, Christian Makwe, Bukola Odusanya, Rose Anorlu, Wasiu Adeyemo, Edna Iroha, Mathias Egri-Okwaji, Prisca Adejumo, Lawal Oyeneyin, Moses Abiodun, Bolaji Badejoko, Kelli Ryckman.

75 FR 51827 - Notice of a Meeting of a Working Group of the NIH Advisory Committee to the Director

Science.gov (United States)

2010-08-23

... Emerging Infectious Diseases Laboratories (NEIDL) at Boston University Medical Campus. The meeting will be... between the Blue Ribbon Panel and the National Research Council Committee on Technical Input (NRC... concerning this meeting, contact Ms. Kelly Fennington, Senior Health Policy Analyst, Office of Biotechnology...

76 FR 72708 - Medicare Program; Renaming and Other Changes to the Advisory Panel on Hospital Outpatient Payment...

Science.gov (United States)

2011-11-25

.... Brian D. Kavanagh, M.D., M.P.H. Judith T. Kelly, B.S.H.A., RHIT, RHIA, CCS. Scott Manaker, M.D., Ph.D.... Pothen, M.S., RHIA, CHPS, CPHIMS, CCS, CCS-P, CHC. Gregory J. Przbylski, M.D. Marianna V. Spanaki-Varela...

Plaadid / Villu Päärt

Index Scriptorium Estoniae

Päärt, Villu, 1972-

2003-01-01

Uutest heliplaatidest "The Very Best of MTV Unplugged", Der Rote Bereich "Risky Business", Jeanette "Rock My Life", Jean-Michel Jarre "Sessions 2000", Zwan "Mary Star Of The Sea", Stevie Wonder "The Definitive Collection", Vince Gill "Next Big Thing", R. Kelly "Chocolate Factory"

Mani, Augustine and the vision of God

African Journals Online (AJOL)

2013-04-10

Apr 10, 2013 ... that is addressed, the sun by day or moon by night. It is specified that the ..... We can continue this 'Manichaean reading' of Augustine's great work with the .... 1999, Copfic documentary texts from Kellis, vol. 1, Oxbow Books ...

75 FR 82066 - Status Report of Water Service, Repayment, and Other Water-Related Contract Actions

Science.gov (United States)

2010-12-29

... DEPARTMENT OF THE INTERIOR Bureau of Reclamation Status Report of Water Service, Repayment, and Other Water- Related Contract Actions AGENCY: Bureau of Reclamation, Interior. ACTION: Notice. SUMMARY... CONTACT: Michelle Kelly, Water and Environmental Services Division, Bureau of Reclamation, P.O. Box 25007...

76 FR 60527 - Status Report of Water Service, Repayment, and Other Water-Related Contract Actions

Science.gov (United States)

2011-09-29

... DEPARTMENT OF THE INTERIOR Bureau of Reclamation Status Report of Water Service, Repayment, and Other Water- Related Contract Actions AGENCY: Bureau of Reclamation, Interior. ACTION: Notice. SUMMARY... CONTACT: Michelle Kelly, Water and Environmental Resources Division, Bureau of Reclamation, P.O. Box 25007...

Why even active people get fatter--the asymmetric effects ofincreasing and decreasing exercise

Energy Technology Data Exchange (ETDEWEB)

Williams, Paul T.

2006-01-06

Background: Public health policies for preventing obesityneed guidelines for active individuals who are at risk due to exerciserecidivism. Methods: Changes in adiposity were compared to the runningdistances at baseline and follow-up in men and women whose reportedexercise increased (N=4,632 and 1,953, respectively) or decreased (17,280and 5,970, respectively) during 7.7 years of follow-up. Results: PerDelta km/wk, decreases in running distance caused over four-fold greaterweight gain between 0-8 km/wk (slope+-SE, males: -0.068+ -0.005 kg/m2,females: -0.080+-0.01 kg/m2) than between 32-48 km/wk (-0.017+-0.002 and-0.010+-0.005 kg/m2, respectively). In contrast, increases in runningdistance produced the smallest weight losses between 0-8 km/wk andstatistically significant weight loss only above 16 km/wk in males and 32km/wk in females. Above 32 km/wk (30 kcal/kg) in men and 16 km/wk (15kcal/kg) in women, weight loss from increasing exercise was equal to orgreater than weight gained with decreasing exercise, otherwise weightgain exceeded weight loss. Substantial weight gain occurred in runnerswho quit running, which would be mostly retained with resumed activity.Conclusion: Public health recommendations should warn against the risksof irreversible weight gain with exercise cessation. Weight gained due toreductions in exercise below 30 kcal/kg in men and 15 kcal/kg in womenmay not be reversed by resuming prior activity. Current IOM guidelines(i.e., maintain total energy expenditure at 160 percent of basal) agreewith the men s exercise threshold for symmetric weight change withchanging exercise levels.

Multivariate analysis of diagnostic parameters derived from whole-kidney and parenchymal time-activity curves

International Nuclear Information System (INIS)

Bergmann, H.; Mostbeck, A.; Samal, M.; Nimmon, C.C.; Staudenherz, A.; Dudczak, R.

2002-01-01

Aim: In a previous work, we have confirmed earlier reports that time-activity curves of renal cortex provide additional useful diagnostic information. The aim of this experiment was to support the finding quantitatively using multiple regression. Materials and Methods: In a retrospective study, we have analyzed MAG3 renal data (90 kidneys in 57 children). Whole-kidney (WK) and parenchymal (PA) time-activity curves were extracted from 20 min pre-diuretic phase using standard WK and parenchymal fuzzy ROIs. Using multiple regression analysis, peak time, mean transit time, output efficiency, and four additional indices of residual activity in WK and PA ROIs were related to the maximum elimination rate (EM) of urine after the diuretic. The kidneys were divided into four groups according to the WK peak time (WKPT): WKPT longer than 0 (all kidneys), 5, 10, and 15 min. Results: Multiple correlation coefficients between the set of WK, PA, and WK+PA curve parameters (independent variables) and the log EM (dependent variable) for each group are summarized. Conclusions: Using pre-diuretic time-activity curves, it is possible to predict diuretic response. This can be useful when interpreting dubious results. Parenchymal curves predict diuretic response better than the whole-kidney curves. With increasing WKPT the whole-kidney curves become useless, while the parenchymal curves are still useful. Using both WK and PA curves produces the best results. This demonstrates that both WK and PA curves carry independent diagnostic information. The contribution obtained from the parenchymal curves certainly worth the difficulties and time required to draw additional ROIs. However, substantial efforts have to be given to the accurate and reproducible definition of parenchymal ROIs

Endocrine studies in ivermectin-treated heifers from birth to puberty.

Science.gov (United States)

Lacau-Mengido, I M; Mejía, M E; Díaz-Torga, G S; Gonzalez Iglesias, A; Formía, N; Libertun, C; Becú-Villalobos, D

2000-04-01

Continuous treatment with ivermectin from birth to puberty advanced sexual maturation by 3.7 wk in Holstein heifers grazing pastures naturally infected with nematodes. Every 14 d jugular blood samples were taken from birth to 45 wk of age from all heifers. No differences in serum FSH, estradiol, or thyroxine levels were observed during the trial between the treated and untreated group. Mean LH levels were diminished in untreated heifers 4 wk before the first estrus and the amplitude of LH pulses was augmented in treated heifers when puberty was reached. Serum IGF-I levels increased from birth to 22 wk of age and then reached a plateau in both groups, but levels were consistently higher in treated heifers from 26 wk of age onward. Body weight gain was retarded in parasitized heifers and IGF-I values were positively correlated with body weight only during the first 20 wk of life. We suggest that enhanced prepubertal IGF-I levels in conjunction with increased prepubertal LH levels and pubertal LH pulse amplitude might be involved in the accelerated somatic maturation and in puberty advancement observed in ivermectin-treated heifers.

Some effects of sarcoptic mange on dogs.

Science.gov (United States)

Arlian, L G; Morgan, M S; Rapp, C M; Vyszenski-Moher, D L

1995-10-01

Sequential changes in pathology were examined for scabies-infested dogs to determine the effects of infestation with Sarcoptes scabiei var. canis. During 8 wk of infestation with S. scabiei, the progression of the disease was evaluated weekly by skin scrape, clinical examination, and blood analyses. At 8 wk, selected organs were microscopically examined for histopathology. All infested dogs developed an advanced level of scabies infestation by 8 wk. Of the 36 blood parameters evaluated, only values for erythrocyte sedimentation rate (ESR) deviated significantly from the normal ranges for dogs. However, infested dogs had significantly (P dogs. Red blood cell levels for infested dogs dropped significantly (P dogs compared to controls, some individual infested dogs exhibited eosinophilia at 4-8 wk of infestation. The ESRs for infested dogs were significantly (P dogs prior to infestation or control dogs. All parameters except neutrophils had returned to preinfestation levels by 2 wk after treatment for scabies. Neutrophil concentrations were no longer significantly different by 4 wk posttreatment. There were no significant differences in serum enzyme, biochemical and electrolyte concentrations between infested and control dogs.(ABSTRACT TRUNCATED AT 250 WORDS)

ANALISIS KOMPETENSI PROFESIONAL GURU ADMINISTRASI PERKANTORAN DALAM PROSES PEMBELAJARAN DI SMK TAMTAMA PREMBUN KABUPATEN KEBUMEN

Directory of Open Access Journals (Sweden)

Diah Ayu

2016-03-01

Full Text Available Tujuan dalam penelitian ini untuk menganalisis dan mendeskripsikan: 1 Kompetensi profesional guru administrasi perkantoran dalam proses pembelajaran, 2 Penerapan kompetensi profesional guru administrasi perkantoran dalam proses pembelajaran. Penelitian ini menggunakan metode penelitian deskriptif persentase. Populasi dalam penelitian ini adalah siswa X, XI, XII program keahlian Administrasi Perkantoran. Pengambilan sampel menggunakan rumus Slovin diperoleh sampel sejumlah 60 siswa. Metode pengumpulan data menggunakan angket dan dokumentasi. Teknik analisis data yang digunakan adalah analisis deskriptif persentase. Hasil penelitian menunjukkan bahwa kompetensi profesional guru administrasi perkantoran dalam proses pembelajaran menunjukkan bahwa 76% dalam kriteria baik. Guru sudah menerapkan kompetensi profesional dalam proses pembelajaran dari indikator keterampilan membuka dan menutup pelajaran sebesar 73% dalam kriteria baik. Indikator keterampilan menjelaskan sebesar 83% dalam kriteria sangat baik. Indikator keterampilan bertanya sebesar 78% dalam kriteria baik. Indikator keterampilan memberi penguatan sebesar 70% dalam kriteria baik. Indikator keterampilan menggunakan media pembelajaran sebesar 63% dalam kriteria baik. Indikator membimbing diskusi kelompok sebesar 81% dalam kriteria baik. Indikator keterampilan mengelola kelas sebesar 85% dalam kriteria sangat baik. Indikator keterampilan mengadakan variasi sebesar 80% dalam kriteria baik. Indikator keterampilan mengajar perorangan dan kelompok kecil sebesar 75% dalam kriteria baik. The purpose of this research is to analyze and describe: 1 teacher's professional competence of the administrative offices in the learning process in vocational Enlisted Prembun Kebumen, (2 Is the professional competence of teachers office administration already applied in the process of learning in vocational Enlisted Prembun Kebumen. The population is students of class X, XI, XII Administrative skills program

ANALISIS PENJUALAN LEMARI ES MEREK LG PADA PT. LG ELECTRONICS INDONESIA CABANG PEKANBARU

Directory of Open Access Journals (Sweden)

Hadiyati Hadiyati

2015-04-01

Full Text Available Abstrak: PT. LG Electronics Indonesia Cabang Pekanbaru merupakan salah satu perusahaan perdagangan yang menjual berbagai macam produk elektronik termasuk  Lemari Es. Penelitian ini bertujuan untuk: (1. Mengetahui penjualan yang dilakukan oleh manajemen PT. LG Electronics Indonesia Cabang Pekanbaru. (2. Mengetahui faktor-faktor yang menyebabkan tidak tercapainya target penjualan Lemari Es Merek LG Pada PT. LG Electronics Indonesia Cabang Pekanbaru. Populasi dalam penelitian ini adalah keseluruhan dari objek yaitu seluruh konsumen Lemari Es merek LG pada PT. LG Electronics Indonesia Cabang Pekanbaru pada tahun 2013 yaitu sebanyak 8.563 orang. Karena keterbatasan penulis, maka diambil sampel yang dianggap mewakili pelanggan yaitu sebanyak 100 orang dengan rumus slovin. Analisis data dilakukan dengan menggunakan metode Analisis Deskriptif. Variabel yang digunakan adalah produk, harga, dan promosi. Berdasarkan hasil penelitian diperoleh, tidak tercapainya target penjualan Lemari Es merek LG pada PT. LG Electronics Indonesia Cabang Pekanbaru karena produk yang ditawarkan belum sepenuhnya sesuai dengan keinginan dan harapan konsumen, harga yang ditawarkan belum sepenuhnya sesuai dengan kondisi ekonomi masyarakat secara umum, serta promosi yang belum maksimal. Abstract: PT. LG Electronics Indonesia Branch of Pekanbaru is one trading company that sells a wide range of electronic products including Refrigerator. This study aims to: (1. Knowing the sales made by the management of PT. LG Electronics Indonesia Branch of Pekanbaru. (2. Knowing the factors that leads failure to achieve sales targets Refrigerator Brand LG At PT. LG Electronics Indonesia Branch of Pekanbaru. The population in this study is the whole of the object that is the entire consumer Refrigerator LG brand in the PT. LG Electronics Indonesia Pekanbaru Branch in 2013 as many as 8563 people. Because of the limitations of the author, then a swab which is considered to represent the customer

PENGARUH KEPRIBADIAN, PENDIDIKAN KEWIRAUSAHAAN, DAN LINGKUNGAN KELUARGA TERHADAP AKTIVITAS BERWIRAUSAHA MAHASISWA UNIVERSITAS NEGERI SEMARANG

Directory of Open Access Journals (Sweden)

Adelina Citradewi

2016-06-01

Full Text Available Berdasarkan data awal penelitian berupa dokumentasi dari Pusbang LKBK Unnes melalui tracer study yang dilakukan terakhir kali pada tahun 2012 diketahui bahwa hanya terdapat 9,3% alumni yang menyatakan bahwa bisnis yang dimilikinya merupakan kelanjutan usaha dari masa kuliah. Penelitian ini bertujuan untuk mengetahui sejauh mana kepribadian, pendidikan kewirausahaan, dan lingkungan keluarga berpengaruh terhadap aktivitas berwirausaha mahasiswa Universitas Negeri Semarang baik secara simultan maupun parsial. Populasi dalam penelitian ini adalah ketua penerima dana Program Kreativitas Mahasiswa Kewirausahaan (PKM-K dan Program Mahasiswa Wirausaha (PMW yang didanai pada tahun 2015 sebanyak 136 mahasiswa dan sampel sebanyak 60 mahasiswa setelah diolah dengan rumus Slovin dengan standar error 10%. Penelitian ini menggunakan angket sebagai alat pengumpulan data. Teknik analisis data menggunakan analisis statistik deskriptif dan analisis regresi berganda. Hasil penelitian menunjukkan bahwa kepribadian, pendidikan kewirausahaan, dan lingkungan keluarga secara simultan berpengaruh positif dan signifikan terhadap aktivitas berwirausaha mahasiswa Universitas Negeri Semarang (26,5%. Secara parsial kepribadian berpengaruh positif dan signifikan (8,24%. Pendidikan kewirausahaan berpengaruh positif namun tidak signifikan (5,34%. Serta lingkungan keluarga berpengaruh positif namun tidak signifikan (4,28%. Based on preliminary data from Pusbang LKBK Semarang State University true tracer study which was done lastly in 2012 knowing that there are only 9,3% of alumni state that his business is the continuation from the effort at collage. This study aims to determine the extent to which personality, entrepreneurship education, and family environment effect on student entrepreneurship activity Semarang State University either simultaneously or partially. The population in this study are the chairmans of fund receiver from Program Kreativitas Mahasiswa Kewirausahaan

FAKTOR-FAKTOR YANG MEMPENGARUHI MINAT SISWA KELAS XI IPS MENGIKUTI EKSTRAKURIKULER EKONOMI AKUNTANSI DI SMA N 4 MAGELANG TAHUN 2015/2016

Directory of Open Access Journals (Sweden)

Laeli Ismiati

2017-06-01

Full Text Available Ekstrakurikuler merupakan kegiatan yang dilakukan diluar jam tatap muka, baik didalam ataupun diluar sekolah dengan tujuan menambah wawasan siswa. Dengan adanya ekstrakurikuler ekonomi akuntansi dalam program sekolah harapannya siswa mempunyai tempat untuk berlatih akuntansi diluar jam mata pelajaran yang terbatas. Namun kenyataannya minat siswa terhadap ekstrakurikuler ekonomi akuntansi di SMA N 4 Magelang masih rendah. Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor yang mempengaruhi minat siswa mengikuti ekstrakurikuler ekonomi akuntansi . Populasi dalam penelitian ini adalah siswa kelas XI IPS SMA N 4 Magelang tahun 2015/2016 yang berjumlah 126. Teknik pengambilan sampel pada penelitian ini menggunakan, proportionate random sampling. Perhitungan jumlah sampel menggunakan rumus slovin dan diketahui jumlah sampel sebesar 96 orang.Metode pengumpulan data menggunakan kuesioner dan metode analisis data menggunakan analisis faktor dengan menggunakan bantuan SPSS v16. Hasil penelitian menunjukkan bahwa terdapat dua faktor yang mempengaruhi siswa mengikuti ekstrakurikuler, yaitu faktor internal dan faktor eksternal. Yang merupakan faktor internal antara lain jasmani, intelegensi, bakat, dan motivasi. Yang merupakan faktor eksternal antara lain pemusatan perhatian, kematangan, lingkungan keluarga, lingkungan sekolah dan lingkungan masyarakat. Variabel yang mempunyai korelasi paling kuat dalam faktor internal adalah intelegensi dengan factor loading sebesar 0,811. Sedangkan dalam faktor eksternal variabel yang mempunyai korelasi paling kuat adalah variabel lingkungan sekolah dengan factor loading sebesar 0,783. Extracurricular is activiti that carried out outside of the classroom, which purpose to improve the student’s knowledge. Economic-Accounting extracurricular in school programs hopes students to get a place to practice accounting outside of the classroom. In fact student’s interest on to Economic-Accounting extracurricular

Dietary guanidinoacetic acid increases brain creatine levels in healthy men

DEFF Research Database (Denmark)

Ostojic, Sergej M; Ostojic, Jelena; Drid, Patrik

2017-01-01

OBJECTIVE: Guanidinoacetic acid (GAA) is an experimental dietary additive that might act as a creatine source in tissues with high-energy requirements. In this case study, we evaluated brain levels of creatine in white matter, gray matter, cerebellum, and thalamus during 8 wk oral GAA......, and 8 wk, the participants underwent brain magnetic resonance spectroscopy, clinical chemistry studies, and open-ended questionnaire for side-effect prevalence and severity. RESULTS: Brain creatine levels increased in similar fashion in cerebellum, and white and gray matter after GAA supplementation......, with an initial increase of 10.7% reported after 4 wk, and additional upsurge (7.7%) from the weeks 4 to 8 follow-up (P creatine levels decreased after 4 wk for 6.5% (P = 0.02), and increased nonsignificantly after 8 wk for 8% (P = 0.09). GAA induced an increase in N-acetylaspartate levels at 8...

Cobalamin status during normal pregnancy and postpartum: a longitudinal study comprising 406 danish women

DEFF Research Database (Denmark)

Milman, N; Byg, KE; Bergholt, T

2006-01-01

-) cobalamin, P-methylmalonic acid and P-homocysteine was measured at 18, 32 and 39 wk gestation and 8 wk postpartum during lactation. RESULTS: P-cobalamin showed a gradual, significant decline during pregnancy (P ... and 8 wk postpartum median values were 225, 172, 161 and 319 pmol/L, respectively. P-methylmalonic displayed a gradual, significant increase during pregnancy as well as postpartum (P homocysteine demonstrated...

Elite synchronized swimmers display decreased energy availability during intensified training.

Science.gov (United States)

Schaal, K; Tiollier, E; Le Meur, Y; Casazza, G; Hausswirth, C

2017-09-01

Elite synchronized swimmers follow high-volume training regimen that result in elevated rates of exercise energy expenditure (ExEE). While adequate energy intake (EI) is important to optimize recovery, a number of sport-specific constraints may lead to chronically low energy availability (EA = EI-ExEE). This study aimed to quantify changes in EA, endocrine markers of energy conservation, and perceived fatigue in synchronized swimmers, during a week of baseline training followed by 4 weeks of intensified training (IT). EI, ExEE, and body composition were measured in nine swimmers at Baseline, midpoint (IT WK 2 ), and end of IT (IT WK 4 ). Waking saliva samples were obtained to measure [leptin] s , [ghrelin] s , and [cortisol] s . Fatigue ratings were provided daily. ExEE increased by 27% during IT. Swimmers increased EI from Baseline to IT WK 2 , but decreased it significantly from IT WK 2 to IT WK 4 . EA, fat mass, and [leptin] s decreased from Baseline to IT WK 4 , while [ghrelin] s increased significantly. Fatigue at IT WK 4 was inversely correlated with Baseline EI and EA. The significant decrease in EA was accompanied by endocrine signs of energy conservation in elite swimmers. As perceived fatigue was associated with low EA, particular attention should be paid to these athletes' energy intake during phases of heavy training. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Efficacy of highly hydrophilic soft contact lenses for persistent corneal epithelial defects after anterior segment surgery

Directory of Open Access Journals (Sweden)

Zhi-Wei Peng

2015-02-01

Full Text Available AIM:To investigate the efficacy of highly hydrophilic soft contact lenses for persistent corneal epithelial defects.METHODS:In this retrospective case analysis, 28 patients(28 eyeswith persistent corneal epithelial defects after anterior segment surgery from January 2011 to June 2013 in our hospital were reviewed. After regular treatment for at least 2wk, the persistent corneal epithelial defects were treated with highly hydrophilic soft contact lenses, until the corneal epithelial healing. Continued to wear the same lens no more than 3wk, or in need of replacement the new one. All cases were followed up for 6mo. Key indicators of corneal epithelial healling, corneal fluorescein staining and ocular symptoms improvement were observed.RESULTS: Twenty-one eyes were cured(75.00%, markedly effective in 5 eyes(17.86%, effective in 2 eyes(7.14%, no invalid cases, the total efficiency of 100.00%. Ocular symptoms of 25 cases(89.29%relieved within 2d, the rest 3 cases(10.71%relieved within 1wk. The corneal epithelial of 6 cases(21.43%repaired in 3wk, 13 cases(46.43%in 6wk, 7 cases(25.00%in 9wk, 2 cases(7.14%over 12wk. There were no signs of secondary infection. And no evidence of recurrence in 6mo. CONCLUSION: Highly hydrophilic soft contact lenses could repair persistent corneal epithelial defects after anterior segment surgery significantly, while quickly and effectively relieve a variety of ocular irritation.

Dose dependent effects of exercise training and detraining ontotal and regional adiposity in 4,663 men and 1,743

Energy Technology Data Exchange (ETDEWEB)

Williams, Paul T.; Thompson, Paul D.

2006-01-06

Objective: To determine if exercise reduces body weight andto examine the dose-response relationships between changes in exerciseand changes in total and regional adiposity. Methods and Results:Questionnaires on weekly running distance and adiposity from a largeprospective study of 3,973 men and 1,444 women who quit running(detraining), 270 men and 146 women who started running (training) and420 men and 153 women who remained sedentary during 7.4 years offollow-up. There were significant inverse relationships between change inthe amount of vigorous exercise (km/wk run) and changes in weight and BMIin men (slope+-SE:-0.039+-0.005 kg and -0.012+-0.002 kg/m2 per km/wk,respectively) and older women (-0.060+-0.018 kg and -0.022+-0.007 kg/m2per km/wk) who quit running, and in initially sedentary men(-0.098+-0.017 kg and -0.032+-0.005 kg/m2 per km/wk) and women(-0.062+-0.023 kg and -0.021+-0.008 kg/m2 per km/wk) who started running.Changes in waist circumference were also inversely related to changes inrunning distance in men who quit (-0.026+-0.005 cm per km/wk) or startedrunning (-0.078+-0.017 cm per km/wk). Conclusions. The initiation andcessation of vigorous exercise decrease and increase body weight andintra-abdominal fat, respectively, and these changes are proportional tothe change in exercise dose.

The effects of a ration change from a total mixed ration to pasture on rumen fermentation, volatile fatty acid absorption characteristics, and morphology of dairy cows.

Science.gov (United States)

Schären, M; Seyfang, G M; Steingass, H; Dieho, K; Dijkstra, J; Hüther, L; Frahm, J; Beineke, A; von Soosten, D; Meyer, U; Breves, G; Dänicke, S

2016-05-01

To investigate the effect of the change from a concentrate and silage-based ration (total mixed ration, TMR) to a pasture-based ration, a 10-wk trial (wk 1-10) was performed, including 10 rumen- and duodenum-fistulated German Holstein dairy cows (182±24 d in milk, 23.5±3.5kg of milk/d; mean ± standard deviation). The cows were divided in either a pasture group (PG, n=5) or a confinement group (CG, n=5). The CG stayed on a TMR-based ration (35% corn silage, 35% grass silage, 30% concentrate; dry matter basis), whereas the PG was gradually transitioned from a TMR to a pasture-based ration (wk 1: TMR only; wk 2: 3 h/d on pasture wk 3 and 4: 12 h/d on pasture wk 5-10: pasture only). Ruminal pH, volatile fatty acids (VFA), NH3-N, and lipopolysaccharide (LPS) concentrations were measured in rumen fluid samples collected medially and ventrally on a weekly basis. Ruminal pH was continuously recorded during 1 to 4 consecutive days each week using ruminal pH measuring devices. In wk 1, 5, and 10, rumen contents were evacuated and weighed, papillae were collected from 3 locations in the rumen, and subsequently a VFA absorption test was performed. In the PG, mean rumen pH and molar acetate proportions decreased, and molar butyrate proportions increased continuously over the course of the trial, which can most likely be ascribed to an increased intake of rapidly fermentable carbohydrates. During the first weeks on a full grazing ration (wk 5-7), variation of rumen pH decreased, and in wk 5 a lower rumen content, papillae surface area, and potential for VFA absorption were observed. In wk 8 to 10, variation of rumen pH and total VFA concentrations increased again, and acetate/propionate ratio decreased. In wk-10 rumen content, papillae area and VFA absorption characteristics similar to initial levels were observed. Although continuous rumen pH assessments and LPS concentrations did not reveal an increased risk for subacute rumen acidosis (SARA) during the adaption period

Association of rumination time with subclinical ketosis in transition dairy cows.

Science.gov (United States)

Kaufman, E I; LeBlanc, S J; McBride, B W; Duffield, T F; DeVries, T J

2016-07-01

The objective of this study was to characterize the relationship between rumination and subclinical ketosis (SCK) in transition dairy cows. A study was conducted on 4 commercial dairy farms in eastern Ontario, Canada. A total of 339 Holstein dairy cows (107 primiparous and 232 multiparous) were monitored for rumination activity and SCK from 14 d before calving until 28 d after calving. Rumination was recorded daily using an automated monitoring system. A blood sample was taken from the coccygeal vein of each cow for measurement of β-hydroxybutyrate (BHB) once weekly throughout the 6-wk observation period. Cows with BHB ≥1.2mmol/L in any of the 4 postpartum samples were considered to have SCK. Cases of retained placenta, metritis, milk fever, or mastitis during the study period were also recorded. Cows were categorized into 1 of 4 groups: healthy cows (HLT) that had no SCK or any other recorded health problem (n=139); cows treated for at least one health issue other than SCK (HLT+; n=50); cows with SCK (hyperketonemia; HYK) with no other health problems during transition (n=97); or cows (HYK+) that had SCK and one or more other health problems (n=53). Daily rumination time was summarized by week and comparisons were made between HLT and HYK and HYK+. From 2 wk before calving (wk -2) to 4 wk after calving (wk +4), there was no difference in rumination time (409±9.8min/d) among HLT, HYK, and HYK+ cows in their first lactation. Multiparous cows in HLT spent an average of 459±11.3min/d ruminating from wk -2 to wk +4. Multiparous HYK cows ruminated 25±12.8min/d less than HLT cows, whereas HYK+ cows ruminated 44±15.6min/d less than HLT cows. The largest differences in rumination time between HLT and HYK+ cows were seen during wk -1, +1, and +2, when HYK+ cows ruminated 48±17.2, 73±16.0, and 65±19.4min/d less than HLT cows, respectively. In multiparous cows, increased odds of HYK were associated with greater milk yield in the previous lactation, greater loss of

77 FR 2992 - Columbia National Wildlife Refuge, Adams and Grant Counties, WA; Final Comprehensive Conservation...

Science.gov (United States)

2012-01-20

...: Kelly Chase, Refuge Manager, (509) 488-2668 (phone); [email protected] (email). SUPPLEMENTARY INFORMATION... Columbia NWR in accordance with the National Wildlife Refuge System Administration Act of 1966 (16 U.S.C... National Wildlife Refuge System, consistent with sound principles of fish and wildlife management...

Knots and Links

Indian Academy of Sciences (India)

in a fashion similar to sound waves, whose medium is air. Ether was believed ..... [3] Colin C Adams, The Knot Book, W H Freeman and Company, New. York. ... [5] Kelly S Chichak, Stuart j CantriU, Antony R Pease, Sheng-Hsien. Chiu, Gareth ...

75 FR 49529 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2010-08-13

... Workers from Express Services and Staffmark. 74,081 General Motors Vehicle Shreveport, LA....... August 28, 2010. Manufacturing, General Motors Corp., Leased Workers Aerotek and Kelly Services. The following... Imaging El Paso, TX January 12, 2009. 73,376 Wacker Neuson Corporation, Menomonee Falls, WI.. January 27...

76 FR 60934 - Proposal Review Panel for Human Resource Development; Notice of Meeting

Science.gov (United States)

2011-09-30

... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Human Resource Development; Notice of...; Proposal Review Panel Human Resource Development ( 1199). Date/Time: November 1, 2011; 5 p.m. to 10 p.m...: Part-Open. Contact Person: Kelly Mack, Division of Human Resource Development, Room 815, National...

75 FR 56141 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2010-09-15

... Electronics Lynchburg, VA May 27, 2009. Corporation, Leased Workers from Alpha Omega, Kelly Services, and Man...,531 Anthem Insurance Companies, Mason, OH August 13, 2009. Inc., Wellpoint, Finance Accounting, Leased Workers from Rogert Half/Accounting etc. The following certifications have been issued. The requirements...

Катриона Келли, Павлик Морозов и Любянка / Юрий Дружников

Index Scriptorium Estoniae

Дружников, Юрий, 1933-2008

2005-01-01

Catriona Kelly uurimusest "Comrade Pavlik. The rise and fall of a soviet boy hero" (2005). J. Družnikov süüdistab C. Kellyt oma raamatu "Pealekaebaja 001" ("Доносчик 001", esitrükk Londonis 1988) plagieerimises

The effect of fermented milk with Bifidobacterium infantis on ...

African Journals Online (AJOL)

STORAGESEVER

2008-11-19

Nov 19, 2008 ... antibiotherapy with amoxicillin and contamination with ... analysis of the stools of 120 infants who were the most affected by ..... competitiveness for sites of adherence (Kelly et al.,. 2006). .... Fingerprinting demonstrates the survival of ... precursor cell increased traffic in allergic subjects an immunology.

"I work all the time- he just waits for the animals to come back": social impacts of climate changes: a Greenlandic case study

NARCIS (Netherlands)

van Voorst, R.

2009-01-01

Understanding human adaptation to climate changes is one of the most important research issues within the area of global environmental change, accounting for the fact that people worldwide are currently adapting to their changing environment (Adger and Kelly 2000: 253; Smit et al. 2008). The

Single-stage repair versus traditional repair of high anorectal ...

African Journals Online (AJOL)

studied and were divided into two groups on the basis of a random number table. ... After clinical evaluation using the Kelly score, patients were divided into three ... All patients were subjected to MRI at the age of 3 years and the findings were ...

77 FR 65384 - Announcement of Intent To Establish the 2015 Dietary Guidelines Advisory Committee and...

Science.gov (United States)

2012-10-26

.../or HHS Co-Executive Secretary, 2015 DGAC: Kellie (O'Connell) Casavale, Ph.D., RD; Office of Disease...; Telephone: (703) 305-7600; Fax: (703) 305-3300. USDA Co-Executive Secretary, Shanthy A. Bowman, Ph.D..., which includes physical activity; nutrient bioavailability; nutrition biochemistry and physiology; food...

78 FR 8147 - Establishment of the 2015 Dietary Guidelines Advisory Committee

Science.gov (United States)

2013-02-05

... Alternate Designated Federal Officer, 2015 DGAC: Kellie (O'Connell) Casavale, Ph.D., RD; Office of Disease...; Telephone: (703) 305-7600; Fax: (703) 305-3300. USDA Co-Executive Secretary, Shanthy A. Bowman, Ph.D...; nutrient bioavailability; nutrition biochemistry and physiology; food processing science, safety and...

76 FR 27669 - Penske Logistics LLC, a Subsidiary of General Electric/Penske Corporation Including On-Site...

Science.gov (United States)

2011-05-12

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,897] Penske Logistics LLC, a Subsidiary of General Electric/Penske Corporation Including On-Site Leased Workers From Kelly Temporary... workers and former workers of Penske Logistics LLC, a subsidiary of General Electric/Penske Corporation...

76 FR 17447 - Penske Logistics LLC a Subsidiary of General Electric/Penske Corporation Including On-Site Leased...

Science.gov (United States)

2011-03-29

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,897] Penske Logistics LLC a Subsidiary of General Electric/Penske Corporation Including On-Site Leased Workers From Kelly Temporary... (TAA) applicable to workers and former workers of Penske Logistics LLC, a subsidiary of General...

78 FR 42805 - HarperCollins Publishers Distribution Operations Including On-Site Leased Workers From Action...

Science.gov (United States)

2013-07-17

... Distribution Operations Including On- Site Leased Workers From Action Personnel, CGA Staffing Services, Dynamic... from Action Personnel, CGA Staffing Services, Dynamic Staffing, Kelly Services, and Manpower, Scranton... (Volume 78 FR Pages 28628-28630). At the request of the State Workforce Office, the Department reviewed...

Muusika DVD-d / Juhan Ulfsak

Index Scriptorium Estoniae

Ulfsak, Juhan, 1973-

2006-01-01

Uute DVD-de Eppu Normaali "Video jää pystyyn", Taraf de Haidouks "The Continuing Adventures Of Taraf de Haidouks, "Kraftwerk "Minimum/Maximum", Judas Priest "Rising In The East", R. Kelly "Trapped In The Closet", Deep Purple "Perihelion", Ray Charles "50 Years In Music"

76 FR 61719 - Notice of a meeting of a working group of the NIH Blue Ribbon Panel

Science.gov (United States)

2011-10-05

... Diseases Laboratories at Boston University Medical Center. The meeting will be held Wednesday, November 2... National Research Council Committee on Technical Input will participate in this discussion and provide its... concerning this meeting, contact Ms. Kelly Fennington, Senior Health Policy Analyst, Office of Biotechnology...

Blast Mitigation Sea Analysis - Evaluation of Lumbar Compression Data Trends in 5th Percentile Female Anthropomorphic Test Device Performance Compared to 50th Percentile Male Anthropomorphic Test Device in Drop Tower Testing

Science.gov (United States)

2016-08-21

Kelly Bosch, PE Proceedings of the ASME 2016 International Design Engineering Technical Conferences & Computers and Information in Engineering...imparted on the occupant • Ideal EA device would reduce peak load and duration to reduce injury probability 5th Percentile Female – 200 g Pulse

Second Chance or No Chance? A Case Study of One Urban Alternative Middle School

Science.gov (United States)

Kennedy-Lewis, Brianna L.

2015-01-01

This qualitative case study focuses on a school created to educate expelled students, specifically examining the relationships between educators' beliefs and philosophies and daily school life. At this school, Kelly's ("Last chance high." Yale University Press, New Haven, 1993) competing philosophies of "traditionalism" and…

76 FR 22923 - Wellpoint, Inc. D/B/A/Anthem Blue Cross & Blue Shield Enterprise Provider Data Management Team...

Science.gov (United States)

2011-04-25

.../B/A/Anthem Blue Cross & Blue Shield Enterprise Provider Data Management Team Including On-Site... & Blue Shield, Enterprise Provider Data Management Team, Including On-Site Leased Workers From Kelly... Of Kentucky, Enterprise Provider Data Management Team, Louisville, Kentucky TA-W-74,895B Wellpoint...

Effect of immunological castration management strategy on lipid oxidation and sensory characteristics of bacon stored under simulated food service conditions.

Science.gov (United States)

Herrick, R T; Tavárez, M A; Harsh, B N; Mellencamp, M A; Boler, D D; Dilger, A C

2016-07-01

The objectives of this study were to determine the effect of 1) immunological castration (Improvest, a gonadotropin releasing factor analog-diphtheria toxoid conjugate) management strategy (age at slaughter and time of slaughter after second dose) and 2) sex on lipid oxidation and sensory characteristics of bacon stored under simulated food service conditions. For Objective 1, immunological castration management strategies included 24-wk-old immunologically castrated (IC) barrows 4, 6, 8, or 10 wk after the second Improvest dose (ASD); 26-wk-old IC barrows 6 wk ASD; and 28-wk-old IC barrows 8 wk ASD ( = 63). Objective 2 ( = 97) included IC barrows, physically castrated (PC) barrows, and gilts slaughtered at 24, 26, and 28 wks of age. Bellies from 2 slaughter dates were manufactured into bacon under commercial conditions. Bacon slices were laid out on parchment paper, packaged in oxygen-permeable poly-vinyl-lined boxes, and frozen (-33°C) for 1, 4, 8, or 12 wk to simulate food service conditions. At the end of each storage period, bacon was evaluated for lipid oxidation, moisture and lipid content, and sensory characteristics. Data from both objectives were analyzed using the MIXED procedure in SAS with belly as the experimental unit. For both objectives, as storage time increased, lipid oxidation of bacon increased ( 0.05). After 12 wk of frozen storage, lipid oxidation values for IC barrows, PC barrows, and gilts were still below 0.5 mg malondialdehyde/kg of meat, the threshold at which trained panelists may deem a food to be rancid. In conclusion, bacon shelf life characteristics were not altered by the immunological castration management strategy and bacon from IC barrows was similar to bacon from gilts. Therefore, bacon from IC barrows would result in shelf life and sensory quality similar to PC barrows and gilts.

Hockey Fans in Training: A Pilot Pragmatic Randomized Controlled Trial.

Science.gov (United States)

Petrella, Robert J; Gill, Dawn P; Zou, Guangyong; DE Cruz, Ashleigh; Riggin, Brendan; Bartol, Cassandra; Danylchuk, Karen; Hunt, Kate; Wyke, Sally; Gray, Cindy M; Bunn, Christopher; Zwarenstein, Merrick

2017-12-01

Hockey Fans in Training (Hockey FIT) is a gender-sensitized weight loss and healthy lifestyle program. We investigated 1) feasibility of recruiting and retaining overweight and obese men into a pilot pragmatic randomized controlled trial and 2) potential for Hockey FIT to lead to weight loss and improvements in other outcomes at 12 wk and 12 months. Male fans of two ice hockey teams (35-65 yr; body mass index ≥28 kg·m) located in Ontario (Canada) were randomized to intervention (Hockey FIT) or comparator (wait-list control). Hockey FIT includes a 12-wk active phase (weekly, coach-led group meetings including provision of dietary information, practice of behavior change techniques, and safe exercise sessions plus incremental pedometer walking) and a 40-wk minimally supported phase (smartphone app for sustaining physical activity, private online social network, standardized e-mails, booster session/reunion). Measurement at baseline and 12 wk (both groups) and 12 months (intervention group only) included clinical outcomes (e.g., weight) and self-reported physical activity, diet, and self-rated health. Eighty men were recruited in 4 wk; trial retention was >80% at 12 wk and >75% at 12 months. At 12 wk, the intervention group lost 3.6 kg (95% confidence interval, -5.26 to -1.90 kg) more than the comparator group (P < 0.001) and maintained this weight loss to 12 months. The intervention group also demonstrated greater improvements in other clinical measures, physical activity, diet, and self-rated health at 12 wk; most sustained to 12 months. Results suggest feasible recruitment/retention of overweight and obese men in the Hockey FIT program. Results provide evidence for the potential effectiveness of Hockey FIT for weight loss and improved health in at-risk men and, thus, evidence to proceed with a definitive trial.

Acute radiation oesophagitis associated with 2-deoxy-2-[18F]fluoro-d-glucose uptake on positron emission tomography/CT during chemo-radiation therapy in patients with non-small-cell lung cancer

International Nuclear Information System (INIS)

Everitt, Sarah; Callahan, Jason; Obeid, Eman; Hicks, Rodney J.; MacManus, Michael; Ball, David

2017-01-01

Acute radiation oesophagitis (ARO) is frequently experienced by patients receiving concurrent chemo-radiation therapy (cCRT) for non-small-cell lung cancer (NSCLC). We investigated ARO symptoms (CTCAE v3.0), radiation dose and oesophageal FDG PET/CT uptake. Candidates received cCRT (60 Gy, 2 Gy/fx) and sequential FDG PET/CT (baseline FDG 0 , FDG wk2 and FDG wk4 ). Mean and maximum standardized uptake value (SUV mean and SUV max ) and radiation dose (O mean and O max ) were calculated within the whole oesophagus and seven sub-regions (5–60 Gy). Forty-four patients underwent FDG 0 and FDG wk2 , and 41 (93%) received FDG wk4 , resulting in 129 PET/CT scans for analysis. Of 29 (66%) patients with ≥ grade 2 ARO, SUVmax (mean ± SD) increased from FDG 0 to FDG wk4 (3.06 ± 0.69 to 3.83 ± 1.27, P = 0.0019) and FDG wk2 to FDG wk4 (3.10 ± 0.75 to 3.83 ± 1.27, P = 0.0046). Radiation dose (mean ± SD) was higher in grade ≥2 patients; O mean (47.5 ± 20 vs 53.9 ± 10.2, P = 0.0061), O max (13.7 ± 9.6 vs 20.1 ± 10.6, P = 0.0009) and V40 Gy (8.0 ± 8.2 vs 11.9 ± 7.3, P = 0.0185). FDG wk4 SUVmax and radiation dose were associated with ≥ grade 2 ARO. Compared to subjective assessments, future interim FDG PET/CT acquired for disease response assessment may also be utilized to objectively characterize ARO severity and image-guided oesophageal dose constraints.

The addition of charcoals to broiler diets did not alter the recovery of Salmonella Typhimurium during grow-out.

Science.gov (United States)

Wilson, K M; Bourassa, D V; Davis, A J; Freeman, M E; Buhr, R J

2016-03-01

Two experiments evaluated prebiotics added to feed on the recovery of Salmonella in broilers during grow-out and processing. In Experiment 1, "seeder" chicks were inoculated with Salmonella Typhimurium and placed with penmates. Treatments were: basal control diet, added 0.3% bamboo charcoal, 0.6% bamboo charcoal, or 0.12% Aromabiotic (medium chain fatty acids). The ceca from seeders and penmates were sampled to confirm Salmonella colonization at 3, 4, and 6 wk, and pen litter was sampled weekly. At 3 wk, charcoal fed chicks had significantly lower cecal recovery (37% lower) of Salmonella via direct plating but no differences at wk 4 or 6. At 6 wk, broilers fed Aromabiotic had no recovery of Salmonella from ceca with direct plating and significantly, 18%, lower recovery with enrichment. In Experiment 2, the treatments were: basal control diet, added 0.3% bamboo charcoal, 0.3% activated bamboo charcoal, or 0.3% pine charcoal. At placement, 2 seeders were challenged with Salmonella and commingled with penmates and ceca sampled at 1 and 2 wk, and ceca from 5 penmates/pen at 3 to 6 wk. Weekly, the pH of the crop and duodenum was measured from 1 penmate/pen and the litter surface sampled. At the end of grow-out broilers were processed. Results showed that penmates had colonized at 1 and 2 wk. Cecal Salmonella showed no differences except at 4 wk, when activated bamboo charcoal had a 18% lower recovery of Salmonella (enrichment) compared to the control (88%). Similar to Experiment 1, the recovery of Salmonella from the litter was not significantly different among treatments, however an overall decrease in recovery by 4 wk with direct plating reoccurred. The pH of the duodenum and the crop were not different among treatments. Crop pH (6.0) for all treatments were significantly higher at wk 1 compared to wk 2 to 6. Charcoals had minimal effect on Salmonella recovery in the ceca, but following defeathering, broilers fed charcoals had significantly lower Salmonella

Six months training alone or combined with diet alters HOMA-AD, HOMA-IR and plasma and adipose tissue adiponectin in obese women.

Science.gov (United States)

Lakhdar, Nadia; Denguezli, Myriam; Zaouali, Monia; Zbidi, Abdelkrim; Tabka, Zouhair; Bouassida, Anissa

2014-01-01

We investigate the effect of 6 months aerobic training alone or in combination with diet on adiponectin in circulation and in adipose abdominal tissue (AT) in obese women. Twenty obese subjects were randomized into a 24 weeks intervention: 1) training (TR) and 2) training and diet (TRD). Blood samples were collected at baseline, after 12 wk and 24 wk. AT biopsies were obtained only at baseline and after 24 wk. In the TRD group the fat loss was after 12 wk -13.74% (pHOMA-IR and HOMA-AD for assessing insulin resistance were strongly affected by protocols. HOMA-IR decreased (pHOMA-AD increased in both groups after 12 (pHOMA-IR.

approximate method for the determination of natural frequencies

African Journals Online (AJOL)

ES Obe

c = √. Gg γ. (3). The vibration of a uniform simply supported beam (Figure 1) generates a ... c fi. (i = 1, 2, 3). (4) where fi = natural frequency of vibration of the bar in the ith mode; ..... Journal sound vibration, 96(4), 437- ... Kelly, S.G. (1993).

77 FR 25199 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2012-04-27

... and Kelly Services. 81,293 NCO Financial Systems, Canonsburg, PA....... February 2, 2011. Inc............ October 1, 2011. Incorporated, On Site: E- Technical, Apple One, Ware Technology Services and Staffing. 81............ April 29, 2011. Shield, Wellpoint, Inc., Service Operations, Blue Cross and Blue Shield in Georgia. 81...

76 FR 57944 - Fisheries of the Northeastern United States; Northeast Multispecies Fisheries, Small-Mesh...

Science.gov (United States)

2011-09-19

... FURTHER INFORMATION CONTACT: Moira Kelly, Fishery Policy Analyst, (978) 281-9218, [email protected] catch (ABC) limits based on recommendations from its Scientific and Statistical Committee (SSC), at its September 2011 meeting. The SSC has recommended separate ABCs by stock or stock group: Northern red hake...

76 FR 60933 - Proposal Review Panel for Human Resource Development; Notice of Meeting

Science.gov (United States)

2011-09-30

... NATIONAL SCIENCE FOUNDATION Proposal Review Panel for Human Resource Development; Notice of..., Proposal Review Panel Human Resource Development ( 1199). Date/Time: October 17, 2011; 5 p.m. to 10 p.m... Meeting: Part-Open. Contact Person: Kelly Mack, Division of Human Resource Development, Room 815, National...

Cannes : türgi eksistentsialism ja ameerika kiirtoit / Annika Koppel

Index Scriptorium Estoniae

Koppel, Annika

2006-01-01

Cannes'i filmifestival. Nähtud filmidest : türklase Nuri Bilge Ceylani "Kliima", soomlase Aki Kaurismäki "Äärelinna tuled", inglase Andrea Arnoldi "Punane tänav" ("Red Road"), ameeriklase Richard Linklateri "Kiirtoidurahvas" ("Fast Food Naton") ja samuti ameeriklase Richard Kelly "Lõuna jutud" ("Southland Tales")

Rescuing Dogs in the Frederick Community | Poster

Science.gov (United States)

Many Frederick National Lab employees have a favorite cause to which they volunteer a significant amount of time. For Dianna Kelly, IT program manager/scientific program analyst, Office of Scientific Operations, and Courtney Kennedy, associate technical project manager, Business Enterprise Systems, that cause is dog rescue.

Thumbnail Images

DEFF Research Database (Denmark)

Thylstrup, Nanna; Teilmann, Stina

2017-01-01

and strategic terms; and a cultural question of how human-computer interaction design works with navigational uncertainty, both as an experience to be managed and a resource to be exploited. This paper considers two copyright infringement cases that involved search engines as defendants, Kelly v. Arriba Soft...

77 FR 51064 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2012-08-23

... Impact date 81,646 CalAmp Wireless Waseca, MN Networks Corporation, Spherion Staffing. 81,697 Global...., Patentes Milwaukee, WI....... Talgo, S.L., Kelly Services, Triada Employment Services & Manpower. 81,791...--search--form.cfm under the searchable listing of determinations or by calling the Office of Trade...

75 FR 75699 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2010-12-06

... Workers College Station, TX.. May 19, 2009. from Kelly Services. 74,286 Pearson Education, Glenview, IL......... June 8, 2009. Curriculum Group Division; Pearson, Inc.; Leased Workers from Corestaff. 74,675... Department. 74,722 Allied Marketing Group....... Dallas, TX. 74,739 Chapman Data Services, Inc... Dallas, TX...

75 FR 45161 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2010-08-02

... 202(b)(1); (B) An affirmative determination of market disruption or threat thereof under section 421(b..., Indotronix and Connexion. 73,966 Nortel Networks, CVAS Test Research Triangle April 19, 2009. Organization... Gretna, VA February 3, 2009. Workers from Kelly Temporary Services. 73,680 Hirschmann Automation and...

Emotional and Personality-Related Aspects of Persistent Career Decision-Making Difficulties

Science.gov (United States)

Saka, Noa; Gati, Itamar

2007-01-01

This study focused on examining the persistent aspects of career decision-making difficulties, using the Emotional and Personality-related Career decision-making Difficulties scale ("EPCD"; [Saka, N., Gati, I., & Kelly, K.R. (in press). Emotional and personality-related aspects of career decision-making difficulties. "Journal of Career…

77 FR 32711 - 30-Day Notice of Proposed Information Collection: DS-234, Special Immigrant Visa Biodata Form...

Science.gov (United States)

2012-06-01

..., Refugees, and Migration, Office of Admissions (PRM/A). Form Number: DS-234. Respondents: Iraqi and Afghan... Population, Refugees and Migration. Dated: May 14, 2012. Kelly A. Gauger, Deputy Director, Office of Admissions, Bureau of Population, Refugees, and Migration, Department of State. [FR Doc. 2012-13343 Filed 5...

77 FR 47669 - Employment and Training Administration

Science.gov (United States)

2012-08-09

... DEPARTMENT OF LABOR Employment and Training Administration TA-W-81,446, Wellpoint, Inc., NE Enrollment and Billing Division, Including On-Site Leased Workers From Aerotek, Kelly Services and Populus Group, North Haven, CT; TA-W-81,446A, Wellpoint, Inc., NE Enrollment and Billing Division, Including On...

76 FR 66931 - Medicare Program: Notice of Two Membership Appointments to the Advisory Panel on Ambulatory...

Science.gov (United States)

2011-10-28

...., FACHE.* David A. Halsey, M.D. Brian D. Kavanagh, M.D., MPH. Judith T. Kelly, R.H.I.T., R.H.I.A., C.C.S. Scott Manaker, M.D., Ph.D. John Marshall, CRA, RCC, CIRCC, RT(R), FAHRA. Agatha Nolan, D.Ph., M.S...

78 FR 75345 - Ocean Transportation Intermediary License Applicants

Science.gov (United States)

2013-12-11

.... Romero, President (QI). Application Type: New NVO & OFF License. F.H.L. Logistics, Inc. (NVO & OFF), 1354.... Officers: Arif H. Butt, General Manager (QI), Unni Krishnan Nair, President. Application Type: New NVO...: Stephen F. Crooks, Vice President (QI), Scott Kelly, President. Application Type: Adding NVO Service...

A Commentary by Chinese Hotel Workers on the Value of Vocational Education.

Science.gov (United States)

Huyton, Jeremy R.; Ingold, Anthony

1999-01-01

An adaptation of Kelly's Repertory Grid was completed by Chinese hotel staff. Results showed they revered higher education qualifications for the prestige and respect they commanded; secondary vocational-technical education was viewed very negatively. However, higher education is typically better funded and staffed than vocational education. (SK)

An Examination of Attitudes towards Women in Leadership Positions in Public Universities in Saudi Arabia

Science.gov (United States)

Alfawzan, Norah Saad

2017-01-01

Despite opportunities for female leadership in the field of higher education made available through gender-segregation policies, women leaders are underrepresented in Saudi Arabia (Jamjoom & Kelly, 2013). There are obstacles that Saudi women face when seeking leadership positions in higher education, including societal attitudes on gender. Due…

75 FR 65431 - Change in Disease Status of Japan Because of Foot-and-Mouth Disease

Science.gov (United States)

2010-10-25

.... Kelly Rhodes, Senior Staff Veterinarian, Regionalization Evaluation Services--Import, National Center... specialty market. Although entities that purchase beef from Japan will be affected by this rule, farms in... the list of FMD-free regions that are subject to certain import restrictions on meat and meat products...

Germination patterns of a suite of semiarid grassland forbs from central New Mexico

Science.gov (United States)

Rosemary L. Pendleton; Burton K. Pendleton

2014-01-01

We examined the germination response of 21 forb species collected from semiarid grasslands of central New Mexico. After-ripened seeds were subjected to 1 of 3 treatments: 1) no treatment; 2) a 3-wk stratification at 5 °C (cold-moist treatment); or 3) a 3-wk warm-moist treatment at 30 °C. All seeds were incubated under an alternating 10/20 °C temperature regime for 6 wk...

Environmental and economic benefits of sustainable development

International Nuclear Information System (INIS)

McKay, P.; Kelly, B.; Passmore, J.

1997-01-01

The panel on sustainable development was moderated by Paul McKay of the Wildside Foundation. Bryan Kelly, Director of Environment and Sustainable Development at Ontario Hydro, and Jeffrey Passmore of Passmore Associates International were the panel members. Bryan Kelly described the objectives of his group's program as reducing market barriers, and get renewables on a level playing field through technological advances to ensure that ' when Ontario Hydro or its successors make decisions about new capacity, renewables will be a viable option and will not be dismissed out of hand'. To illustrate the approach, he described several ongoing research and development projects. Jeffrey Passmore reported on a study he conducted for the Canadian Wind Energy Association and Environment Canada to determine the environmental and economic benefits of wind energy in Canada. He estimated achievable wind energy potential in Canada at around 6400 MW by 2010. He stressed wind energy's potential for job creation and CO 2 reduction as the principal economic and environmental benefits

A “New Irish Woman” Emerges: Subverting Femininity in Maeve Kelly’s A Life of Her Own

Directory of Open Access Journals (Sweden)

Ángela Rivera Izquierdo

2017-03-01

Full Text Available Women in Irish fiction have been largely the creation of male writers, and the embodiment of religious virtues such as purity and passivity, conventionally regarded as “feminine.” Not only the Roman Catholic Church but also the State progressively contributed to the social construct of Irish womanhood as inferior and, above all, domestic. From the 1960s onwards many women writers have tried relentlessly to reimage women in their fiction. Feminist activist Maeve Kelly is an outstanding example of such writers whose work remains virtually unexplored. Very often Kelly’s protagonists are women in their conventional roles as wives and mothers who struggle for happiness and independence. This essay focuses on her collected stories A Life of Her Own (1976, and particularly on her short story “The vain woman,” in which Kelly presents us with a “new Irish woman” who is no longer the personification of the Virgin Mary, and who actively rebels against her environment.

Space shuttle crew training at CERN

CERN Multimedia

Paola Catapano

From 13 to 16 October, the crew of NASA Space Shuttle mission STS-134 came to CERN for a special physics training programme. Invited here by Samuel Ting, they will deliver the Alpha Magnetic Spectrometer (AMS) detector to the International Space Station (ISS).   The STS134 crew in the Lodge at the Aiguille du Midi wearing CERN fleeces. From left to right: Captain Mark Kelly, US Navy; Pilot Gregory Johnson, USAF ret.; Mission Specialist Andrew Feustel; Mission Specialist Mike Fincke, USAF, Mission Specialist Gregory Chamitoff and Mission Specialist Roberto Vittori, ESA and Italian Air Force. Headed by Commander Mark Kelly, a US Navy captain, the crew included pilot Gregory Johnson, a US Air Force (USAF) colonel, and mission specialists Mike Fincke (also a USAF Colonel), Andrew Feustel, and Gregory Chamitoff of NASA, as well as Colonel Roberto Vittori of the European Space Agency (ESA). Two flight directors, Gary Horlache and Derek Hassmann of NASA, and the engineer responsible for the Ext...

Hepatitis C virus therapy with peg-interferon and ribavirin in Myanmar: A resource-constrained country.

Science.gov (United States)

Hlaing, Naomi Khaing Than; Banerjee, Debolina; Mitrani, Robert; Arker, Soe Htet; Win, Kyaw San; Tun, Nyan Lin; Thant, Zaw; Win, Khin Maung; Reddy, K Rajender

2016-11-21

To investigate peg-interferon (peg-IFN) and ribavirin (RBV) therapy in Myanmar and to predict sustained virologic response (SVR). This single-center, open-label, study was conducted in Myanmar between 2009 and 2014. A total of 288 patients infected with HCV genotypes 1, 2, 3 and 6 were treated with peg-IFN alpha-2a (180 μg/wk) or alpha-2b (50 to 100 μg as a weight-based dose) and RBV as a weight-based dose (15 mg/kg/d). Treatment duration was 48 wk for genotypes 1 and 6, 24 wk for genotype 2, and 24 or 48 wk for genotype 3 based on rapid virologic response (RVR). Those co-infected with hepatitis B received 48 wk of therapy. Overall, SVR was achieved for 82% of patients and the therapy was well tolerated. All patients achieved SVR at equivalent rates regardless of HCV genotype ( P = 0.314). Low fibrosis scores ( P 96% positive predictive value for achieving SVR. Treatment duration did not significantly impact the likelihood of achieving SVR for patients infected with genotype 3 HCV ( P = 0.371). The most common adverse events were fatigue (71%) and poor appetite (60%). Among patients with genotype 3 HCV, more patients in the 48-wk treatment group required erythropoietin than in the 24-wk treatment group (61.1% vs 49.2%). SVR rates were high with peg-IFN and RBV therapy in Myanmar. Fibrosis scores, baseline albumin, HCV RNA levels and RVR independently predicted SVR.

Cardiac atrophy after bed rest and spaceflight

Science.gov (United States)

Perhonen, M. A.; Franco, F.; Lane, L. D.; Buckey, J. C.; Blomqvist, C. G.; Zerwekh, J. E.; Peshock, R. M.; Weatherall, P. T.; Levine, B. D.

2001-01-01

Cardiac muscle adapts well to changes in loading conditions. For example, left ventricular (LV) hypertrophy may be induced physiologically (via exercise training) or pathologically (via hypertension or valvular heart disease). If hypertension is treated, LV hypertrophy regresses, suggesting a sensitivity to LV work. However, whether physical inactivity in nonathletic populations causes adaptive changes in LV mass or even frank atrophy is not clear. We exposed previously sedentary men to 6 (n = 5) and 12 (n = 3) wk of horizontal bed rest. LV and right ventricular (RV) mass and end-diastolic volume were measured using cine magnetic resonance imaging (MRI) at 2, 6, and 12 wk of bed rest; five healthy men were also studied before and after at least 6 wk of routine daily activities as controls. In addition, four astronauts were exposed to the complete elimination of hydrostatic gradients during a spaceflight of 10 days. During bed rest, LV mass decreased by 8.0 +/- 2.2% (P = 0.005) after 6 wk with an additional atrophy of 7.6 +/- 2.3% in the subjects who remained in bed for 12 wk; there was no change in LV mass for the control subjects (153.0 +/- 12.2 vs. 153.4 +/- 12.1 g, P = 0.81). Mean wall thickness decreased (4 +/- 2.5%, P = 0.01) after 6 wk of bed rest associated with the decrease in LV mass, suggesting a physiological remodeling with respect to altered load. LV end-diastolic volume decreased by 14 +/- 1.7% (P = 0.002) after 2 wk of bed rest and changed minimally thereafter. After 6 wk of bed rest, RV free wall mass decreased by 10 +/- 2.7% (P = 0.06) and RV end-diastolic volume by 16 +/- 7.9% (P = 0.06). After spaceflight, LV mass decreased by 12 +/- 6.9% (P = 0.07). In conclusion, cardiac atrophy occurs during prolonged (6 wk) horizontal bed rest and may also occur after short-term spaceflight. We suggest that cardiac atrophy is due to a physiological adaptation to reduced myocardial load and work in real or simulated microgravity and demonstrates the plasticity

Wkład Vladislava Vančury w rozwój czeskiej kinematografii

OpenAIRE

WALCZAK, Małgorzata

2011-01-01

Autorka opisuje znaczenie Vladislav Vančura dla rozwoju kinematografii czeskiej, która została uznana przez niego za nową sztukę. Przedstawia ona wypowiedzi pisarza na temat filmu i kina zawartego w zbiorze pt. Řád nové tvorby. Autorka podkreśla nowość w podejściu do kinematografii, która opiera się głównie na artystycznym eksperymencie. Wskazuje na fakt, że w opinii pisarza, film jest utworzony przez wielu specjalistów. Vančura bowiem postulował wprowadzenie szkolnictwa filmowego, co korespo...

Suitability of groundwater and surface water for drinking and ...

African Journals Online (AJOL)

Water quality for irrigation purpose were determined by sodium absorption ratio, soluble sodium percentage (SSP), magnesium adsorption ratio (MAR), Kelly's ratio (KR), permeability index (PI), residual sodium bicarbonate (RSC) to investigate an eventual ionic toxicity of water on soil and plants. In this study, HCO3- is ...

Enriching Critical Thinking and Language Learning with Educational Digital Libraries

Science.gov (United States)

Lu, Hsin-lin

2012-01-01

As the amount of information available in online digital libraries increases exponentially, questions arise concerning the most productive way to use that information to advance learning. Applying the earlier information seeking theories advocated by Kelly (1963), Taylor (1968), and Belkin (1980) to the digital libraries experience, Carol Kuhlthau…

Operational art in the Defense: The German Abwehrschlachten in 1918

Science.gov (United States)

2012-05-17

Siegismund, 1937), 74. 21 Jacob Jung, Max von Gallwitz (1852-1937) (Osnabrück: Biblio -Verlag, 1995), 93 & 97. 22 Erich Ludendorff, Meine...Goerre-Verlag, 2003. 44 Jung, Jakob. Max von Gallwitz (1852-1937). Osnabrück: Biblio -Verlag, 1995. Kelly, Justin, and Michael J. Brennan. "The

What do Polish and Dutch consumers think about dried fruit and products with them - creaiwe group discussions as a means of recognittion consumers'perception

NARCIS (Netherlands)

Jesionkowska, K.; Konopacka, D.; P¿ocharski, W.; Sijtsema, S.J.; Zimmermann, K.L.

2007-01-01

The main aim of the study was to get insight into consumers' perception towards dried fruit and products with them, thus the exploratory study designed as a group discussion took place. While group discussions association (as one of the projective technique) and Kelly repertory grid were used to

Molecular Imaging with Quantum Dots Probing EMT and Prostate Cancer Metastasis in Live Animals

Science.gov (United States)

2006-10-01

ACKNOWLEDGMENTS We thank Yuanyuan Cui, Shari Kelly and Carol Phillips for technical supports and Gary Mawyer for editing. The study was supported by R01...589-596. 47. Mendez O, Fernandez Y, Peinado MA, et al. Anti-apoptotic proteins induce non- random genetic alterations that result in selecting breast

78 FR 54643 - KC Scoby Hydro, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

Science.gov (United States)

2013-09-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14526-000] KC Scoby Hydro... Intervene, and Competing Applications On May 28, 2013, KC Scoby Hydro, LLC, filed an application for a... Contact: Kelly Sackheim, KC Scoby Hydro, LLC, 5096 Cocoa Palm Way, Fair Oaks, CA 95628; phone: (301) 401...

Trefoil factors in human milk

DEFF Research Database (Denmark)

Vestergaard, Else Marie; Nexø, Ebba; Wendt, A

2008-01-01

We measured concentrations of the gastrointestinal protective peptides Trefoil factors in human milk. By the use of in-house ELISA we detected high amounts of TFF3, less TFF1 and virtually no TFF2 in human breast milk obtained from 46 mothers with infants born extremely preterm (24-27 wk gestation......), preterm (28-37 wk gestation), and full term (38-42 wk gestation). Samples were collected during the first, second, third to fourth weeks and more than 4 wks postpartum. Median (range) TFF1 [TFF3] concentrations in human milk were 320 (30-34000) [1500 (150-27,000)] pmol/L in wk 1, 120 (30-720) [310 (50......-7100)] pmol/L in wk 2, 70 (20-670) [120 (20-650)] pmol/L in wks 3 to 4, and 60 (30-2500) [80 (20-540)] pmol/L in > 4 wks after delivery. The lowest concentrations of TFF1 and TFF3 were found later than 2 wks after birth. In conclusion, TFF was present in term and preterm human milk with rapidly declining...

Growth of juvenile green iguanas (Iguana iguana) fed four diets.

Science.gov (United States)

Donoghue, S

1994-12-01

Wild green iguanas consume a primarily folivorous diet. As pets in captivity, they suffer high mortality and malnutrition. Nutrient requirements are not established. The purpose of this study was to compare growth in juvenile iguanas fed three commercial diets and a romaine-based diet. Twelve nominally 4-wk-old iguanas were fed in a latin square design each of four diets for 8 wk, consisting of a 2-wk accommodation period and a 6-wk collection period. Diets were analyzed at the beginning and end of the study. Food consumption was measured daily; body weights and lengths were measured weekly. For Diets A, B, C and D mean body weight gains were--3, 6, 31 and 60% in 6 wk, respectively. Gain in body weight and snout-vent length increased linearly with dietary protein and fiber and with dry matter intake. The data suggest that growth in pet green iguanas may achieve rates for farmed and wild green iguanas when diets are palatable and contain adequate protein and fiber.

Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women.

Science.gov (United States)

Heinrich, Ulrike; Moore, Carolyn E; De Spirt, Silke; Tronnier, Hagen; Stahl, Wilhelm

2011-06-01

Dietary constituents including polyphenols and carotenoids contribute to endogenous photoprotection and modulate skin characteristics related to structure and function of the tissue. Animal and in-vitro studies indicate that green tea polyphenols affect skin properties. In a 12-wk, double-blind, placebo-controlled study, 60 female volunteers were randomized to an intervention or control group. Participants consumed either a beverage with green tea polyphenols providing 1402 mg total catechins/d or a control beverage. Skin photoprotection, structure, and function were measured at baseline (wk 0), wk 6, and wk 12. Following exposure of the skin areas to 1.25 minimal erythemal dose of radiation from a solar simulator, UV-induced erythema decreased significantly in the intervention group by 16 and 25% after 6 and 12 wk, respectively. Skin structural characteristics that were positively affected included elasticity, roughness, scaling, density, and water homeostasis. Intake of the green tea polyphenol beverage for 12 wk increased blood flow and oxygen delivery to the skin. Likewise, in a separate, randomized, double-blind, single-dose (0.5, 1.0, and 2.0 g) study of green tea polyphenols, blood flow was maximized at 30 min after ingestion. In summary, green tea polyphenols delivered in a beverage were shown to protect skin against harmful UV radiation and helped to improve overall skin quality of women.

A comparative study on the transplantation of different concentrations of human umbilical mesenchymal cells into diabetic rats

Institute of Scientific and Technical Information of China (English)

Jia-Hui; Kong; Dan; Zheng; Song; Chen; Hong-Tao; Duan; Yue-Xin; Wang; Meng; Dong; Jian; Song

2015-01-01

AIM: To observe the effects of intravitreal injections of different concentrations of human umbilical mesenchymal stem cells on retinopathy in rats with diabetes mellitus.METHODS: Healthy and adult male Sprague-Dawley(SD) rats were randomly assigned to a normal control group(group A), a diabetic retinopathy(DR) blank control group(group B), a high-concentration transplantation group(group C), a low-concentration transplantation group(group D) and a placebo transplantation group(group E). The expression of nerve growth factor(NGF)protein in the retinal layers was detected by immunohistochemical staining at 2, 4, 6 and 8wk.RESULTS: The expression of NGF was positive in group A and most positive in the retinal ganglion cell layer. In groups B and E, the expression of NGF was positive 2wk after transplantation and showed an increase in all layers. However, the level of expression had decreased in all layers at 4wk and was significantly reduced at 8wk. In groups C and D, the expression of NGF had increased at 2wk and continued to increase up to 8wk. The level of expression in group C was much higher than that in group D.CONCLUSION: DR can be improved by intravitreal injection of human umbilical mesenchymal stem cells.High concentrations of human umbilical mesenchymal stem cells confer a better protective effect on DR than low concentrations.

Structural modifications in the arterial wall during physiological aging and as a result of diabetes mellitus in a mouse model: are the changes comparable?

Science.gov (United States)

Prévost, G; Bulckaen, H; Gaxatte, C; Boulanger, E; Béraud, G; Creusy, C; Puisieux, F; Fontaine, P

2011-04-01

Vascular accelerated aging represents the major cause of morbidity and mortality in subjects with diabetes mellitus. In the present study, our aim was to compare premature functional and morphological changes in the arterial wall resulting from streptozotocin (STZ)-induced diabetes mellitus in mice over a short-term period with those that develop during physiological aging. The effect of aminoguanidine (AG) on the prevention of these alterations in the diabetic group was also analyzed. The vascular relaxation response to acetylcholine (ACh) in the mouse was tested in isolated segments of phenylephrine (Phe)-precontracted aorta at 2, 4 and 8 weeks (wk) of STZ-induced diabetes and compare to 12- and 84-wk-old mice. Aortic structural changes were investigated, and receptor for AGE (RAGE) aortic expression was quantified by western blot. Compared to the 12-wk control group (76 ± 5%), significant endothelium-dependant relaxation (EDR) impairment was found in the group of 12-wk-old mice, which underwent a 4-wk diabetes-inducing STZ treatment (12wk-4WD) (52 ± 4%; P aging preventive effect on the structural changes of the arterial wall. Our study compared EDR linked to physiological aging with that observed in the case of STZ-induced diabetes over a short-term period, and demonstrated the beneficial effect of AG. Copyright © 2010 Elsevier Masson SAS. All rights reserved.

PENGARUH ATMOSFER GERAI DAN PELAYANAN RITEL TERHADAP NILAI HEDONIK DAN PEMBELIAN IMPULSIF PELANGGAN MATAHARI DEPARTMENT STOREDUTA PLAZA DI DENPASAR

Directory of Open Access Journals (Sweden)

Ni Nyoman Manik Yistiani

2012-11-01

Full Text Available The purpose of this research to determine the effect of atmospheric outlet and retail services toward impulsive buying through hedonic value. In this research examined four variables, namely atmospheric outlet, retail services, hedonic value as well as impulsive buying. The location of this research is at Matahari Departement Store Duta Plaza, in Denpasar with the target of population who purchase more than two times. The sample is taken by purposive sampling method.Based on Slovin formula, the number of sample about 168 consumer.Statistical Analysis was used to the test the hypothesis is Equation Model Structure (SEM. The main finding showed that the better atmospheric outlet will increase hedonic value and impulsive buying.  Similarly,the better retail service will increase hedonic value and impulsive buying, but hedonic value not able to act as pemediasi of the relationship between atmospheric outlet and retail services toward impulsive buying. Therefore from the side of Matahari Departement Store Duta Plaza, Denpasar is expected to pay more attention to its atmospheric outlet and retail service in order to increase hedonic value and impulsivebuying

Kecenderungan Sivitas Akademika dalam Memilih Sumber Referensi untuk Penyusunan Karya Tulis Ilmiah di Perguruan Tinggi

Directory of Open Access Journals (Sweden)

Wahyu Supriyanto

2017-06-01

Full Text Available Libraries are many stores various reference sources. Library became one of the places to study science. UGM Library has a data includes printed books, electronic books, print journals, online journals, scientific papers lecturer repository. One of the users of the library are Gadjah Mada University academic community who come to the library to look for references to make scientific papers. This study aims to determine the level of user visits a library in one week and knowing the tendency of academics looking for the source of reference in the manufacture of scientific papers. This research using quantitative descriptive method with a sample of 982 based on the formula Slovin. The results showed that; 1. Academics often visit both physical and virtual library by 53% with the intensity of visits 1-2 times a week 2. UGM academic community were divided into 4 groups (Agrokomplek, Health, Saintek, SocioHumanities shows that most online journal as a reference as a source of scientific reference of 22.65%.

Computed tomographic analysis of tibiotarsal bone mineral density and content in turkeys as influenced by age and sex

International Nuclear Information System (INIS)

Charuta, A.; Cooper, R.G.; Pierzchala, M.; Horbanczuk, J.O.

2012-01-01

Changes in the volumetric bone mineral density (vBMD) and bone mineral content (BMC) of tibiotarsal bones of growing turkeys as affected by birds' age, sex, and within-the-bone location, respectively, were determined by computed tomography. The research was performed on 165 heavy-type BIG 6 turkeys reared between weeks (wk) 3-16 of age. The computed tomography measurement, conducted at 18 and 50% of the bone length, comprised a bone fragment which was 0.07 mm thick for the compact and the spongious substance collectively. It should be noted that the diaphyses of the tibiotarsal bones in turkeys (580 mg/cubic cm) had significantly greater vBMD than the proximal metaphyses (300 mg/cubic cm). BMC was higher in metaphyses for both sexes. Significant differences between the BMC of the metaphyses and the diaphyses were observed in males and females at wk 3, 6 and 9, and at wk 3 and 12, respectively. vBMD in the diaphyses gradually attenuated with age for both sexes, from 688 mg/cubic cm (wk 3) to 532 mg/cubic cm (wk 16). vBMD of the metaphyses was constant in females, but in males it achieved maximum values of 350 mg/cubic cm at wk 6 and 12 and minimum of 260 mg/cubic cm at wk 9 and 16. Correlations between body weight and vBMD of the diaphyses were observed in males (r = -0.85, P less than 0.001) and females (r = -0.52, P less than 0.01). It can be concluded that vBMD loss in diaphyses diminished bone-breaking strength leading in investigated turkeys to deformities and bone fractures

Multidisciplinary approach to evaluating welfare of veal calves in commercial facilities.

Science.gov (United States)

Stull, C L; McDonough, S P

1994-09-01

Due to pending legislation and public concerns, a multidisciplinary approach was designed to investigate the welfare of special-fed veal calves in commercial veal facilities. Concerns included housing conditions, dietary regimens, management practices, and behavioral aspects imposed on special-fed calves. Four categories of parameters including environment and housing, nutrition, health and stress, and behavior provided a broad base of evaluating veal systems. Observations and samples were collected on 550 Holstein bull calves located in 10 commercial veal facilities. Each facility was visited to collect data during wk 0 (week of arrival of the calves), 2, 4, 8, 12, and 16. Nine facilities used individual stalls 48 to 55 cm in width with tethers attached to the front of the stalls. One facility housed 30 calves in group pens after obtaining calves at 8 wk of age. Ammonia, carbon monoxide, and hydrogen sulfide gas did not exceed the permissible limit for humans in any facility. All facilities exceeded the 2-foot-candle recommendation for lighting. The average daily gain of calves was .85 kg during wk 0 to 8 and 1.18 kg during wk 8 to 16. Dietary iron levels decreased from 209 ppm at wk 0 to 32 ppm at wk 16. At 16 wk, 25% of calves were marginally anemic and 10% clinically anemic. Overall mortality was 4.2%. Stress indices such as plasma cortisol concentrations or neutrophil to lymphocyte ratios declined as calves approached market weight. In either pens or stalls, calves spent approximately 25 and 75% of time in standing and lying positions, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

Oral toxicity study of tragacanth gum in B6C3F1 mice: development of squamous-cell hyperplasia in the forestomach and its reversibility.

Science.gov (United States)

Hagiwara, A; Tanaka, H; Tiwawech, D; Shirai, T; Ito, N

1991-10-01

Tragacanth gum was administered at dietary levels of 0 (control), 0.625, 1.25, 2.5, and 5.0% to groups of 10 male and 10 female B6C3F1 mice for 13 wk. There were no treatment-associated effects regarding clinical signs, body or organ weights, and urinalysis or hematology data. Significant dose-related, but slight, elevations of plasma gamma-glutamyl transpeptidase (GGT) level were observed in all treated animals except the 0.625% females. Single or small numbers of tiny nodules were observed on the luminal surface of the forestomach in 4 males of the 5.0% group, 2 males of the 2.5% group, and 1 male each from the 1.25 and 0.625% groups. Histopathologically, they were diagnosed as squamous-cell hyperplasia. To investigate the nature of these gross lesions, tragacanth gum was fed to groups of 30 male mice at the dietary level of 5.0% for periods of up to 48 wk; 20 males served as controls. There were no treatment-related increases of plasma GGT levels at wk 24 and 48. Although squamous-cell hyperplasias were seen in 2 out of 10 mice at wk 24, none of these proliferative lesions were apparent at wk 48, after either chronic exposure or 24 wk on basal diet. Furthermore, the levels of DNA synthesis in forestomach epithelium as measured by 5-bromo-2-deoxyuridine (BrdU) immunohistochemistry were comparable to control values at wk 24 and 48. Thus, the oral toxicity of tragacanth gum to B6C3F1 mice was concluded to be negligible.

Vision Restoration with a Collagen Cross-linked Boston Keratoprosthesis Unit

Science.gov (United States)

2017-09-01

Esen Akpek 4 W.K. Kellogg Eye Center Dr. Shahzad Mian 5 The Jules Stein Eye Institute Dr. Anthony Aldave 6 Illinois Eye and Ear Infirmary Dr. Jose...Principal Investigator 1 Mass Eye and Ear Infirmary Dr. Joseph Ciolino 3 The Willmer Eye Institute Dr. Esen Akpek 4 W.K. Kellogg Eye Center Dr...Dr. Esen Akpek 4 W.K. Kellogg Eye Center Dr. Shahzad Mian 5 The Jules Stein Eye Institute Dr. Anthony Aldave 7 Cincinnati Eye Institute Dr. Edward

Impact of Skip-a-Day and Every-Day Feeding Programs for Broiler Breeder Pullets on the Recovery of Salmonella and Campylobacter following challenge.

Science.gov (United States)

Wilson, K M; Bourassa, D V; McLendon, B L; Wilson, J L; Buhr, R J

2018-06-08

The impact of restrictive feeding programs on Salmonella and Campylobacter colonization and persistence after challenge was investigated for broiler breeder pullets housed in an experimental rearing facility. Pullet-chicks were placed on litter in 3 feeding program rooms and each room contained 2 replicate pens. The feeding programs were: (1) Skip-a-day in trough feeders (SAD); (2) Every-day in trough feeders (EDT); (3) Every-day on the pen litter (EDL). On d 1, an additional group of hatchmate chicks were housed in a separate room and gavaged with Salmonella Typhimurium, to later serve as seeder chicks. After seeders were confirmed Salmonella-positive at wk 4, at wk 5 seeders were placed into each feeding program pen to commingle with 135 penmates. At 7, 9, 11, 17, 18, and 20 wk the litter surface in each pen was sampled using intermittently stepped-on drag-swabs. At 8, 12, 16, and 20 wk of age the ceca were sampled from 10 penmates/pen and 2 pooled spleen samples/pen were collected. SAD litter remained Salmonella-positive through 20 wk of age while EDL and EDT pens had no detectible litter Salmonella recovery by 18 and 20 wk. EDL fed pens had no direct (days had significantly higher Salmonella recovery (40%), compared to EDT and EDL (both at 5% recovery). By 16 and 20 wk, only the SAD pullets on the on-feed day (48 h without feed) had recovery of Salmonella at 20%. Salmonella recovery in pooled spleen samples did not appear associated with feeding treatments (22% positive). The remaining pullets challenged with Campylobacter at 21 wk produced similar trends as was seen for Salmonella. SAD program pullets had significantly higher Campylobacter from ceca (80 to 100%) compared to pullets on EDL (30 to 60%) or EDT (40 to 95%). These results suggest that using a Skip-a-Day feeding program for broiler breeder pullets contributes to persistently higher Salmonella and Campylobacter ceca colonization and litter prevalence.

Energy partitioning and thyroid hormone levels during Salmonella enteritidis infections in pullets with high or low residual feed intake.

Science.gov (United States)

Van Eerden, E; Van Den Brand, H; Heetkamp, M J W; Decuypere, E; Kemp, B

2006-10-01

This experiment was conducted to investigate whether feed efficiency, as measured by residual feed intake as a phenotypic trait, affects energy partitioning in pullets that have received Salmonella inoculation as an immune challenge. In each of 8 trials, energy partitioning was measured during 5 wk in 15-wk-old efficient (R-) and nonefficient (R+) pullets, which were housed per efficiency group in 2 identical climate respiration chambers. After 1 wk of adaptation, the pullets in 4 trials were orally inoculated with 10(8) cfu of Salmonella enteritidis; pullets in the remaining trials were not inoculated and served as controls. Heat production was calculated from continuous recordings of O(2) consumption and CO(2) production. Energy and N partitioning were recorded on a weekly basis. Blood samples for analyses on thyroid hormones were taken at 16, 17, and 19 wk of age. There were no interactions between efficiency type and Salmonella treatment or Salmonella treatment effects in energy partitioning, except for a short-term increase in heat production in inoculated pullets. Nonefficient pullets had higher gross energy and ME intake, higher estimated ME for maintenance, lower ME:gross energy ratio, and higher total heat production and nonactivity-related heat production compared with R- pullets. Triiodothyronine levels in R+ pullets were higher at 16 and 17 wk but were lower at 19 wk of age compared with R- pullets. Thyroxine levels were higher in R- at 16 wk and showed interactions between efficiency type and Salmonella treatment at 17 and 19 wk of age. Body weights and spleen weights did not differ between efficiency groups. Nonefficient pullets had higher heart, liver, and ovary weights and more large yellow follicles than R- pullets. There were no Salmonella effects on body and organ weights. We conclude that R+ pullets have a faster running energy metabolism and that they put more resources into organ development than R- pullets. Inoculation with Salmonella has a

Altitude Training in Elite Swimmers for Sea Level Performance (Altitude Project).

Science.gov (United States)

Rodríguez, Ferran A; Iglesias, Xavier; Feriche, Belén; Calderón-Soto, Carmen; Chaverri, Diego; Wachsmuth, Nadine B; Schmidt, Walter; Levine, Benjamin D

2015-09-01

This controlled, nonrandomized, parallel-groups trial investigated the effects on performance, V˙O2 and hemoglobin mass (tHbmass) of four preparatory in-season training interventions: living and training at moderate altitude for 3 and 4 wk (Hi-Hi3, Hi-Hi), living high and training high and low (Hi-HiLo, 4 wk), and living and training at sea level (SL) (Lo-Lo, 4 wk). From 61 elite swimmers, 54 met all inclusion criteria and completed time trials over 50- and 400-m crawl (TT50, TT400), and 100 (sprinters) or 200 m (nonsprinters) at best stroke (TT100/TT200). Maximal oxygen uptake (V˙O2max) and HR were measured with an incremental 4 × 200 m test. Training load was estimated using cumulative training impulse method and session RPE. Initial measures (PRE) were repeated immediately (POST) and once weekly on return to SL (PostW1 to PostW4). tHbmass was measured in duplicate at PRE and once weekly during the camp with CO rebreathing. Effects were analyzed using mixed linear modeling. TT100 or TT200 was worse or unchanged immediately at POST, but improved by approximately 3.5% regardless of living or training at SL or altitude after at least 1 wk of SL recovery. Hi-HiLo achieved greater improvement 2 (5.3%) and 4 wk (6.3%) after the camp. Hi-HiLo also improved more in TT400 and TT50 2 (4.2% and 5.2%, respectively) and 4 wk (4.7% and 5.5%) from return. This performance improvement was not linked linearly to changes in V˙O2max or tHbmass. A well-implemented 3- or 4-wk training camp may impair performance immediately but clearly improves performance even in elite swimmers after a period of SL recovery. Hi-HiLo for 4 wk improves performance in swimming above and beyond altitude and SL controls through complex mechanisms involving altitude living and SL training effects.

[Changes of CD(4)(+) Foxp3+ regulatory T cells and CD(4)(+)IL-17+T cells in acrolein exposure rats].

Science.gov (United States)

Wei, Ming; Tu, Ling; Liang, Yinghong; Li, Jia; Gong, Yanjie; Zhang, Yihua; Yang, Lu

2015-09-01

To evaluate the changes of CD(4)(+) IL-17+T (Th17) and CD(4)(+)Foxp3+regulatory T (Treg) cells in peripheral blood and bronchoalveolar lavage fluid (BALF) , and therefore to explore the role of Th17 and Treg in acrolein exposure airway inflammation in rats. Forty male Wistar rats were randomly divided into 4 groups: a 2 wk acrolein exposure group, a 4 wk acrolein exposure group, a 2 wk control group and a 4 wk control group (n=10 each). Cells in BALF were collected and analyzed by absolute and differential cell counts.IL-17 and IL-6 levels in serum and BALF were tested by enzyme linked immunosorbent assay (ELISA). The proportion of CD(4)(+)IL-17+T and CD(4)(+) Foxp3+Treg in peripheral blood and BALF were determined by flow cytometry.The mRNA expressions of IL-17 and Foxp3 were measured by real-time PCR. Comparisons of the data between different groups were performed using one-way ANOVA, and SNK and Games-Howell test were used for comparison between 2 groups. Levels of IL-17 were remarkable increased in the 2 wk acrolein exposure group and the 4 wk acrolein exposure group in serum [(52.64 ± 1.89) ng/L, (76.73 ± 5.57) ng/L], and BALF [(79.07 ± 5.67) ng/L, (96.61 ± 6.44) ng/L] compared with the 2 wk control group [(40.05 ± 3.12) ng/L, (56.75 ± 4.37) ng/L] and the 4 wk control group [(38.75 ± 3.23) ng/L, (53.27 ± 4.48) ng/L], all Pcells and macrophages (r=0.5126, 0.5437, all Pcells and an vary of inflammatory cytokines were evident in airway inflammation of acrolein exposed rats, suggesting that Treg was involved in the immunological regulation and Th17 was associated with the persistent inflammation in acrolein induced airway inflammation in rats.

[Changes of CD(4)(+)Foxp3(+) regulatory T cells and CD(4)(+)IL-17(+)T cells in cigarette smoke-exposed rats].

Science.gov (United States)

Meng, Jing-jing; Zhong, Xiao-ning; Bai, Jing; He, Zhi-yi; Zhang, Jian-quan; Huang, Qiu-pin

2012-01-01

To evaluate the changes of CD(4)(+)IL-17(+) T (Th17) and CD(4)(+)Foxp3(+) regulatory T (Treg) cells in peripheral blood and bronchoalveolar lavage fluid (BALF), and therefore to explore the role of Th17 and Treg in cigarette smoke-induced airway inflammation/COPD in rats. Forty male Wistar rats were randomly divided into 4 groups: a 12 wk smoke-exposure group, a 24 wk smoke-exposure group, a 12 wk control group and a 24 wk control group (n = 10 each). Cells in BALF were collected and analyzed by absolute and differential cell counts. IL-17 and IL-6 levels in serum and BALF were tested by enzyme linked immunosorbent assay (ELISA). The proportion of CD(4)(+)IL-17(+) T and CD(4)(+)Foxp3(+) Treg in peripheral blood and BALF were determined by flow cytometry. The mRNA expressions of IL-17 and Foxp3 were measured by real-time PCR. Comparisons of the data between different groups were performed using one-way ANOVA, and SNK and Games-Howell test were used for comparison between 2 groups. Levels of IL-17 were remarkable increased in the 12 wk smoke-exposure group and the 24 wk smoke-exposure group in serum [(52.6 ± 1.8) ng/L, (75.4 ± 6.0) ng/L] and BALF [(78.1 ± 5.8) ng/L, (95.0 ± 6.8) ng/L] compared with the 12 wk control group [(40.0 ± 3.2)ng/L, (54.5 ± 4.6) ng/L] and the 24 wk control group [(36.7 ± 3.2) ng/L, (53.9 ± 3.7) ng/L], all P cells and macrophages (r = 0.512, 0.543, all P cells and an increase of inflammatory cytokines were evident in airway inflammation of cigarette smoke-exposed rats, suggesting that Treg was involved in the immunological regulation and Th17 was associated with the persistent inflammation in cigarette smoke-induced airway inflammation in rats.

Benjamin Vassermanile preemiad

Index Scriptorium Estoniae

2007-01-01

Graafik Benjamin Vasserman pälvis kolme digitaalse graafilise lehe eest žürii kiituse Ungaris Györis toimunud biennaalil "The Master of Drawing and Graphic Arts" ning II preemia nelja lehe eest Leedus Vilniuses toimunud VI rahvusvahelisel väikegraafika triennaalil. Eestist osalesid veel Reti Saks ja Kelli Valk

78 FR 58534 - Warm Springs Irrigation District; Notice of Technical Meeting

Science.gov (United States)

2013-09-24

... confertiflora requested by the U.S. Bureau of Land Management on June 7, 2013; the coordination of the National... Agenda: 1. Introduction. 2. Meeting objectives. 3. Plant survey discussion. 4. NEPA coordination. 5... phone. Please contact Kelly Wolcott at [email protected] or (202) 502-6480 by close of business...

77 FR 63714 - Airworthiness Directives; The Boeing Company Airplanes

Science.gov (United States)

2012-10-17

.... ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for certain The Boeing... instructions and doing the work specified in those instructions. We are issuing this AD to detect and correct..., Room W12-140, 1200 New Jersey Avenue SE., Washington, DC 20590. FOR FURTHER INFORMATION CONTACT: Kelly...

76 FR 20034 - Calvin Ramsey, M.D.; Revocation of Registration

Science.gov (United States)

2011-04-11

... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-25] Calvin Ramsey, M.D.; Revocation of Registration On December 18, 2009, the Deputy Assistant Administrator, Office of Diversion... constitutional right to appointed counsel in a proceeding under 21 U.S.C. 824(a). See Goldberg v. Kelly, 397 U.S...

78 FR 78786 - Fisheries of the Northeastern United States; 2014 Commercial Summer Flounder Quota Adjustments

Science.gov (United States)

2013-12-27

... 31, 2014. FOR FURTHER INFORMATION CONTACT: Moira Kelly, Fishery Policy Analyst, (978) 281-9218... fisheries. Specifications in these fisheries include the acceptable biological catch (ABC) limit, various... 2014 specifications million lb mt million lb mt ABC 22.24 10,088 21.94 9,950 Commercial ACL 12.05 5,467...

identification of common bean genotypes with dual leaf and pod ...

African Journals Online (AJOL)

ACSS

2018-02-08

Feb 8, 2018 ... IDENTIFICATION OF COMMON BEAN GENOTYPES WITH DUAL LEAF AND. POD RESISTANCE TO COMMON BACTERIAL BLIGHT DISEASE IN UGANDA. B.M.E. ALLADASSI, S.T. NKALUBO1, C. MUKANKUSI2, H.N. KAYAGA, P. GIBSON, R. EDEMA,. C.A. URREA3, J.D. KELLY4 and P.R. RUBAIHAYO.

Disarming the Threat to Feminist Identification: An Application of Personal Construct Theory to Measurement and Intervention

Science.gov (United States)

Moradi, Bonnie; Martin, Annelise; Brewster, Melanie E.

2012-01-01

Many individuals endorse feminist values but do not identify as feminist. The present set of studies tests the concept of threat, grounded in G. A. Kelly's personal construct theory of personality, as a potential factor in feminist nonidentification. Study 1 introduces the theoretically grounded "Feminist Threat Index" and evaluates its…

Effect of 2 Bedding Materials on Ammonia Levels in Individually Ventilated Cages

Science.gov (United States)

2016-01-01

Koontz,1* David M Kumsher,2 Richard Kelly III,3 and Jonathan D Stallings1 This study sought to identify an optimal rodent bedding and cage-change...March 2015]. Available at: http://www.ssponline.com/. 15. Silverman J, Bays DW, Cooper SF, Baker SP. 2008. Ammonia and carbon dioxide concentrations

History of the software industry: the challenge

NARCIS (Netherlands)

G. Alberts (Gerard); A. van den Bogaard; M. Campbell-Kelly; F. Veraart

2005-01-01

textabstractMartin Campbell-Kelly opened a new field in the history of computing in his groundbreaking From airline reservation to Sonic the Hedgehog; a history of the software industry. The book is discussed by Adrienne van den Bogaard and Frank Veraart and by Gerard Alberts, followed by a reply by

Threat and Guilt Aspects of Internalized Antilesbian and Gay Prejudice: An Application of Personal Construct Theory

Science.gov (United States)

Moradi, Bonnie; van den Berg, Jacob J.; Epting, Franz R.

2009-01-01

Building on G. A. Kelly's (1991a, 1991b) personal construct theory, this study introduced concepts of threat and guilt as different manifestations of internalized antilesbian and gay prejudice. Results with 102 lesbian and gay participants indicated that internalized threat and guilt each accounted for unique variance in global internalized…

Further Food for Thought on the "ABS Guide"

Science.gov (United States)

Hussain, Simon

2012-01-01

This paper replies to points raised by the editors of the "ABS Guide", Huw Morris, Charles Harvey, Aidan Kelly and Michael Rowlinson (2011) "Accounting Education: an international journal", 20(6), pp. 561-573) in response to a paper published in a previous issue of "Accounting Education" (Hussain, S. (2011)…

75 FR 54957 - Qualification of Drivers; Exemption Applications; Vision

Science.gov (United States)

2010-09-09

... highway operating conditions: Rick A. Ervin, Stephen P. Goodall, John R. Kelly, Osvaldo R. Maldonado, Frank G. Merrill, Alberto Mireles, Jr., Montie Price, Daniel R. Rosas, David M. Sims, Stephen W... pounds for all or part of the 3-year period: Adam O. Carson, Joe H. Saine, Joseph W. Schmit. One...

Enhancing Authentic Leadership-Followership: Strengthening School Relationships

Science.gov (United States)

Crippen, Carolyn

2012-01-01

Much has been written about leadership in schools, but little mention has been made of followership. The article provides an awareness and foundation for future discussions about school followership. In 1992, Robert Kelly wrote "The Power of Followership," which explains and analyses the world of followers and their relationship to…

Improving Cultural Competency and Disease Awareness among Oncology Nurses Caring for Adult T-Cell Leukemia and Lymphoma Patients

Science.gov (United States)

Cortese-Peske, Marisa A.

2013-01-01

Foreign-born residents face significant challenges accessing and receiving quality healthcare in the U.S. These obstacles include a lack of information on how to access care, fear, as well as communication and cultural barriers (Portes, Fernandez-Kelly & Light, 2012). Increasing healthcare providers' knowledge regarding a patient's…

Effects of positive relative accommodation on adolescent pseudomyopia with visual training

Directory of Open Access Journals (Sweden)

Jiang Yue

2014-04-01

Full Text Available AIM:To investigate the changes of the positive relative accommodation in adolescent pseudomyopia with visual training.METHODS: A total of 42 cases(84 eyeswere randomly divided into the visual training group and the control group. Visual acuity, average refraction of two groups 4wk after the training were measured, as well as positive relative accommodation(5mwere checked before the training and repeated 1, 2, 4wk after the training. Correlation analysis were given.RESULTS: There was statistically significant difference in visual acuity 4wk after the training between the two groups(PP>0.05. There was statistically significant difference in positive relative accommodation(5m1, 2, 4wk after the training between the two groups(PPCONCLUSION: Visual training has significant effect on the positive relative accommodation on adolescent pseudomyopia.

20. september 2008 - tähtis päev / Kelly Kipper

Index Scriptorium Estoniae

Kipper, Kelly

2008-01-01

Ilmunud ka: Eesti Eest = Za Estoniju : Izdanije objedinenija "Sojuz Otetshestva i Res Publica" 18. sept. lk. 7. Autor räägib Noorte Konservatiivide ja Noor-Isamaa ühinemisest ja sellest, miks seda varem pole tehtud

Determinism and Underdetermination in Genetics: Implications for Students' Engagement in Argumentation and Epistemic Practices

Science.gov (United States)

Jiménez-Aleixandre, María Pilar

2014-01-01

In the last two decades science studies and science education research have shifted from an interest in products (of science or of learning), to an interest in processes and practices. The focus of this paper is on students' engagement in epistemic practices (Kelly in "Teaching scientific inquiry: Recommendations for research and…

Philanthropy and Educational Reform during the Great Depression

Science.gov (United States)

Watras, Joseph

2005-01-01

The author discusses philanthropy and educational reform from the Great Depression to the present, contrasting the views of that time to "Making It Count" (Chester E. Finn, Jr. and Kelly Amis, 2001.) Although Finn and Amis presented their suggestions as advancing democracy, they thought that educational reform took place best when elite groups…

Kontserdisari kutsub "Klavessiinisalongi"

Index Scriptorium Estoniae

2008-01-01

Rakvere Kaurikooli saalis toimuvatest kontsertidest: 7. dets."iViva Espagna!" (esinevad klavessiiniduo Ene Nael - Kristiina Are ja näitleja Tarmo Song), 15. veebr. "Häälemeelne" (laulja Kelli Pärnaste ja kitarrist Tiit Korsar, klavessinist Ene Nael) ja 26. apr. "Fiori musicali" (Tallinna Vanalinna Hariduskolleegiumi, Tallinna Muusikakeskkooli ja Rakvere Kaurikooli klavessiiniõpilased)

The Department of Defense and Climate Change: Initiating the Dialogue

Science.gov (United States)

2012-01-01

Edward Franchi NRL 202.404.8690 edward.franchi@nrl.navy.mil David Kriebel USNA 410.293.6432 kriebel@usna.edu Kelly Burks-Copes USACE... rule , the area of numerical modeling/simulations do not work well in these “tail” areas—these are the events that really “bite you.” The current

Workplace Flexibility: From Research to Action

Science.gov (United States)

Galinsky, Ellen; Sakai, Kelly; Wigton, Tyler

2011-01-01

Ellen Galinsky, Kelly Sakai, and Tyler Wigton explore the "time famine" among American workers--the continuing sense among employees of not having enough time to manage the multiple responsibilities of work and personal and family life. Noting that large shares of U.S. employees report feeling the need for greater workplace flexibility…

Let Peter Rabbit Play in the Garden: Using Beatrix Potter's Work to Integrate Ecological Literacy into Montessori Classrooms

Science.gov (United States)

Johnson, Kelly

2015-01-01

Kelly Johnson introduces a series of lessons that incorporate literacy, observation, botany, history, place studies, writing, and art, with a long-term eco-literacy goal of connectedness and a conservation ethic. Johnson's initial idea to use Beatrix Potter as a model in the Lower Elementary classroom came after extensively researching…

Effective State, Local, and Tribal Police Intelligence: The New York City Police Department’s Intelligence Enterprise -- A Smart Practice

Science.gov (United States)

2010-03-01

2008d; Kelly, 2009a, 2009b, and 2009c). (2) Jakarta, Hotel Bombings, July 17, 2009. • Synchronized bombings of JW Marriott and Ritz - Carlton ...critical response vehicles—police cars and officers—to Marriott, Ritz - Carlton , and other hotels in NYC “within 30 minutes of the attacks.” • NYPD ILU

Phenotypic and genetic analysis of Lymantria dispar nucleopolyhedrovirus few polyhedra mutants: Mutations in the 25K FP gene may be caused by DNA replication errors

Science.gov (United States)

David S. Bischoff; James M. Slavicek

1997-01-01

We previously demonstrated that polyhedron formation (PF) mutants arise at a high frequency during serial passage of the Lymantria dispar nucleopolyhedrovirus (LdMNPV) in the L. dispar 652Y cell line (J.M. Slavicek, N. Hayes-Plazolles, and M.E. Kelly, Biol. Control 5:251-261, 1995). Most of these PF mutants...

Rühmanäitus võib olla ka kunstnike mesallianss / Anne Lõugas

Index Scriptorium Estoniae

Lõugas, Anne, 1951-

2002-01-01

1.-23. III Kastellaanimajas avatud taani ja eesti graafikute ühisnäitusest "Hjorring - Tallinn". Evi Tihemets, Kelli Kagovere ja Urmas Viik eksponeerivad Taanis Hjorringis ning taanlased Maegens Larsen Stenderup, Per Borge Maltesen ja Lars Pedersen Tallinnas sügisel 2001 valminud töid. Pikemalt U. Viigi ofsettlitost "Vigala, 26. 07. 1939"

78 FR 5385 - Endangered and Threatened Wildlife and Plants; Endangered Status for Four Central Texas...

Science.gov (United States)

2013-01-25

...... 68 (28) 6. Hogg Hollow Spring Unit...... Private, Federal.. 68 (28) 7. Cedar Hollow Spring Unit............ Private 68 (28) 10. Avant Spring Unit Private 68 (28) 11. Buford Hollow Spring Unit... Federal, Private.... Blizzard R-Bar-B Spring Unit Private 88 (36) 11. House Spring Unit Private 68 (28) 12. Kelly Hollow Spring...

Effect of early exposure to mixed rations differing in forage particle size on feed sorting of dairy calves.

Science.gov (United States)

Miller-Cushon, E K; Montoro, C; Bach, A; DeVries, T J

2013-05-01

Feed sorting of dairy cattle is influenced by dietary forage particle size. The objective of this study was to determine the effect of early exposure to rations differing in forage particle size on development of feed sorting in dairy calves. Twenty Holstein bull calves were exposed for 8 wk to 1 of 2 mixed rations containing (on a dry-matter basis) 90% crumb starter concentrate and either (1) 10% coarsely chopped (3- to 4-cm) grass hay (CRS; n=10) or (2) 10% finely ground (2-mm) grass hay (FN; n=10), both offered ad libitum. Calves received 8L of milk replacer/d (1.2 kg of dry matter/d), with the amount progressively reduced after 5 wk, to facilitate weaning by the end of wk 7. At the beginning of wk 9, all calves received the CRS diet and were followed for 3 wk. Intake was recorded daily and calves were weighed twice per week. Samples of fresh feed and orts were taken on d 1 to 4 of wk 9 and 11 for analysis of feed sorting. Sorting of the ration was assessed through analysis of nutrient intake. Actual intake of each nutrient was expressed as a percentage of predicted intake of that nutrient, based on the concentration in the fresh sample. Daily dry matter intake (DMI) was similar between treatments after transition to the common CRS ration (3.20 kg/d, standard error=0.25 kg/d). However, feed efficiency was subject to a treatment-by-week interaction, with calves previously fed the FN diet having an initially greater gain-to-feed ratio than those fed the CRS diet [in wk 9, 0.60 vs. 0.47 kg of average daily gain (ADG)/kg of DMI] and similar feed efficiency in the following weeks (in wk 10, 0.43 vs. 0.43 kg of ADG/kg of DMI). A corresponding tendency was observed for ADG and body weight to evolve differently, depending on treatment, with calves previously fed the FN diet having greater ADG initially (in wk 9, 1.60 vs. 1.32 kg/d) but similar ADG to those fed the CRS diet in the following weeks (in wk 10, 1.39 vs. 1.33 kg/d and in wk 11, 1.32 vs. 1.31 kg/d). Calves

Frequency of Intake and Type of Away-from- Home Foods Consumed Are Associated with Diet Quality in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Science.gov (United States)

McClain, Amanda C; Ayala, Guadalupe X; Sotres-Alvarez, Daniela; Siega-Riz, Anna Maria; Kaplan, Robert C; Gellman, Marc D; Gallo, Linda C; Van Horn, Linda; Daviglus, Martha L; Perera, Marisa J; Mattei, Josiemer

2018-03-01

Away-from-home foods (AFHFs) influence diet quality, a modifiable obesity risk factor, with limited generalizable evidence in Hispanic/Latino adults. We investigated associations between AFHF intake with diet quality and overweight or obesity among US Hispanic/Latino adults. Cross-sectional baseline (2008-2011) analyses included adults (n = 16,045) aged 18-74 y in the national Hispanic Community Health Study/Study of Latinos. Participants self-reported AFHF consumption frequency from 10 different settings and dietary intake (2-d 24-h recall). The Alternate Healthy Eating Index-2010 (AHEI-2010) was used to measure diet quality; higher scores indicated a healthier diet and scores were categorized into tertiles. WHO classifications categorized overweight [body mass index (BMI; kg/m2): 25.0-29.9] and obesity (BMI ≥30). Multivariate-adjusted associations of AFHF frequency or type with AHEI-2010, overweight, or obesity were assessed by using complex survey logistic regression (ORs and 95% CIs). Almost half of participants (47.1%) reported eating AFHFs ≥5 times/wk. The mean ± SE AHEI-2010 score was 47.5 ± 0.2. More than one-third (37.2%) were classified as overweight and 39.6% classified as obese. Compared with consuming AFHFs ≥5 times/wk, consuming AFHFs <1 time/wk or 1-2 times/wk was associated with greater odds of being in higher AHEI-2010 tertiles, indicating a healthier diet [<1 time/wk-tertile 2: OR (95% CI): 1.6 (1.4, 1.9); tertile 3: 2.5 (2.1, 3.1); 1-2 times/wk-tertile 2: OR (95% CI): 1.4 (1.2, 1.6); tertile 3: 1.5 (1.2, 1.8)]. Consumption of AFHFs ≥1 time/wk from each AFHF setting, compared with consumption of any AFHFs <1 time/wk was associated with lower odds of being in higher AHEI-2010 tertiles. Increasing AFHF intake frequency was not associated with odds of overweight or obesity. Eating from on-street vendors ≥1 time/wk was associated with obesity (OR: 1.5; 95% CI: 1.1, 2.0). Consumption of AFHFs was prevalent among Hispanic/Latino adults and

Greater early and mid-pregnancy gestational weight gain are associated with increased risk of gestational diabetes mellitus: A prospective cohort study.

Science.gov (United States)

Zhong, Chunrong; Li, Xiating; Chen, Renjuan; Zhou, Xuezhen; Liu, Chaoqun; Wu, Jiangyue; Xu, Shangzhi; Wang, Weiye; Xiao, Mei; Xiong, Guoping; Wang, Jing; Yang, Xuefeng; Hao, Liping; Yang, Nianhong

2017-12-01

Gestational diabetes mellitus is associated with adverse short- and long-term consequences for both the mother and the offspring. To examine the relationship between the rates of gestational weight gain (RGWG) during early and mid-pregnancy and the risk of gestational diabetes mellitus (GDM). 2090 singleton pregnant women from the Tongji Maternal and Child Health Cohort (TMCHC) without overt diabetes before pregnancy were analyzed in our study. Gestational weight were measured regularly in every antenatal visit. Gestational diabetes mellitus was assessed with the 75-g, 2-h oral glucose tolerance test at 24-28 weeks of gestation. Multivariable logistic regression was performed to estimate effect of RGWG on GDM. A total of 8.3% (n = 173) of pregnant women were diagnosed with GDM. Women with elevated rate of gestational weight gain prior to glucose screening test (RGWG-PG) increased the risk of GDM (adjusted p-trend = 0.004; odds ratios (OR) 1.64, 95% confidence intervals (CI) 1.01-2.68 and OR 2.30,95% CI 1.44-3.66 for 0.297-0.384 kg/wk and 0.385 kg/wk or more vs. 0.213 kg/wk or less, respectively). Women with greater rate of gestational weight gain in the first trimester (RGWG-F) increased the risk of GDM (adjusted p-trend = 0.048; OR 1.83, 95% CI 1.14-2.94 and OR 1.76, 95% CI 1.10-2.83 for 0.086-0.200 kg/wk and 0.201 kg/wk or more vs. -0.025 kg/wk or less, respectively). The rate of gestational weight gain in the second trimester (RGWG-S) was significantly associated with GDM only among women with RGWG-F more than 0.086 kg/wk (adjusted p-trend = 0.035; OR 2.04, 95% CI 1.16-3.59 for 0.658 kg/wk or more vs. 0.418 kg/wk or less). Greater early pregnancy weight gain are associated with increased risk of GDM. Elevated weight gain in mid-pregnancy increased the risk of GDM only among pregnant women with greater weight gain in the first trimester. Copyright © 2017 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All

Effect of plane of milk replacer intake and age on glucose and insulin kinetics and abomasal emptying in female Holstein Friesian dairy calves fed twice daily.

Science.gov (United States)

MacPherson, J A R; Berends, H; Leal, L N; Cant, J P; Martín-Tereso, J; Steele, M A

2016-10-01

The objective of this study was to investigate how preweaning plane of milk replacer intake and age can affect insulin and glucose kinetics as well as abomasal emptying rate in dairy calves fed twice a day. A total of 12 female Holstein Friesian calves were blocked by cow parity, paired by colostrum origin, and were randomly assigned to a high plane of milk replacer intake (8 L/d, 1.2kg of milk replacer/d; n=6) or a low plane of nutrition (4 L/d, 0.6kg of milk replacer/d; n=6). All calves received 4 L of colostrum over 2 meals (1 and 6h after birth) and were then directly transferred to their assigned feeding plans until they were stepped-down from milk by 50% during wk 7 and weaned on wk 8. Milk replacer (24% crude protein, 18% crude fat) was fed at 150g/L twice daily (0700 and 1700h) and all calves had ad libitum access to pelleted calf starter, chopped wheat straw, and water. Jugular catheters were placed in all calves at 4, 7, and 10wk of age. Then, postprandial response to plasma glucose, insulin, and acetaminophen (supplied with the meal) were determined to measure abomasal emptying. The next day, a glucose tolerance test was conducted by infusing glucose via the jugular catheter. At 4 and 7wk of age, the rate constant (%/h) for abomasal emptying of the meal was lower in high calves (0.21±0.02 in wk 4; 0.27±0.02 in wk 7) compared with low (0.34±0.02 in wk 4; 0.47±0.02 in wk 7). The postprandial plasma insulin area under the curve over 420min was greater in high calves (18,443±7,329; low=5,834±739 µU/mL) compared with low. We found no differences in glucose tolerance test kinetics between the high and low dairy calves at 4, 7, or 10wk of age. The findings from this study suggest that feeding dairy calves an elevated plane of nutrition in 2 meals of milk replacer per day does not decrease insulin sensitivity. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Predictive value of symptoms and demographics in diagnosing malignancy or peptic stricture

Science.gov (United States)

Murray, Iain A; Palmer, Joanne; Waters, Carolyn; Dalton, Harry R

2012-01-01

AIM: To determine which features of history and demographics predict a diagnosis of malignancy or peptic stricture in patients presenting with dysphagia. METHODS: A prospective case-control study of 2000 consecutive referrals (1031 female, age range: 17-103 years) to a rapid access service for dysphagia, based in a teaching hospital within the United Kingdom, over 7 years. The service consists of a nurse-led telephone triage followed by investigation (barium swallow or gastroscopy), if appropriate, within 2 wk. Logistic regression analysis of demographic and clinical variables was performed. This includes age, sex, duration of dysphagia, whether to liquids or solids, and whether there are associated features (reflux, odynophagia, weight loss, regurgitation). We determined odds ratio (OR) for these variables for the diagnoses of malignancy and peptic stricture. We determined the value of the Edinburgh Dysphagia Score (EDS) in predicting cancer in our cohort. Multivariate logistic regression was performed and P 73 years, OR 1.1-3.3, age 73 years 11.8%, P dysphagia (≤ 8 wk, OR 4.5-20.7, 16.6%, 8-26 wk 14.5%, > 26 wk 2.5%, P dysphagia (food or drink sticking within 5 s of swallowing than those who did not (15.1% vs 5.2% respectively, P dysphagia (pharyngeal level dysphagia 11.9% vs mid sternal or lower sternal dysphagia 12.4%). Peptic stricture was statistically more frequent in those with longer duration of symptoms (> 6 mo, OR 1.2-2.9, ≤ 8 wk 9.8%, 8-26 wk 10.6%, > 26 wk 15.7%, P 73 years 10.6%, P dysphagia. The predictive value for associated features could help determine need for fast track investigation whilst reducing service pressures. PMID:22969199

CHANGES IN RESTING SALIVARY TESTOSTERONE, CORTISOL AND INTERLEUKIN-6 AS BIOMARKERS OF OVERTRAINING.

Science.gov (United States)

Anderson, Travis; Haake, Simon; Lane, Amy R; Hackney, Anthony C

2016-01-01

Overtraining (OVT) is a concern for many athletes. Immunological (increased interleukin-6 [IL-6]) and hormonal (increased cortisol [C], decreased free testosterone [fT]) biomarkers have been analyzed during training to detect OVT development. This study determined if resting levels of salivary IL-6, T, and C change during a pre-season resistance training (RT) program in 20 Division I American football players (mean ± SD: age = 19.1 ± 1.1 years; height = 185.4 ± 6.7 cm; mass = 102.0 ± 22.2 kg; body fat = 14.7 ± 7.6%). 1RM squat, bench press and Olympic-style clean, IL-6, C and T were assessed at baseline (WK1), week 4 (WK4), week 6 (WK6) along with psychological status (PS) to determine affective state. 1RM (bench press: 121.6 ± 36.3 kg vs. 127.4 ± 35.9 kg, squat: 187.2 ± 30.2 kg, 190.9 ± 28.1 kg, clean: 116.8 ± 14.6 kg, vs. 119.2 ± 14.5 kg), IL-6 (1.42 ± 1.77 pg/mL vs. 5.60 ± 12.57 pg/mL) and C (2.57 ± 2.46 nmol/L vs. 5.33 ± 4.94) increased signihcantly from WK1 to WK6 ( p < .05), fT decreased signihcantly (417.44 ± 83.63 pmol/Lvs. 341.10 ± 87.79 pmol/L) from WK1 to WK6 ( p < .05). PS was minimally affected during the study. Signihcant biomarker changes were detected, but no OVT was induced (i.e. performance improved). Therefore, directional changes in these biomarkers may not be sufficiently reflective of OVT in RT programs.

Efficacy of Bistrifluron Termite Bait on Coptotermes lacteus (Isoptera: Rhinotermitidae) in Southern Australia.

Science.gov (United States)

Webb, Garry A

2017-08-01

Bistrifluron, a benzoylphenyl urea compound, was evaluated for efficacy against Coptotermes lacteus (Froggatt), a mound-building species in southern Australia. Bistrifluron bait (tradename Xterm) was delivered as containerized pellets inserted into plastic in-ground feeding stations implanted in the sides of mounds. Termites actively tunneled in the gaps between pellets and removed bait from the canisters. Two separate trials were conducted, one commencing on 22 September 2011 and the second commencing on 30 November 2011. In trial 1, all 13 treated colonies (seven single and six double treatments) were eliminated within 19 wk, while all five untreated colonies remained healthy. In trial 2, all four treated colonies were eliminated within 14 wk. In trial 1, bait consumed or removed in treated mounds averaged 105 g for single treatments and 147 g for dual treatments, and overall ranged from 7 to 309 g (70-3,090 mg bistrifluron). In trial 2, the four treated colonies removed an average of 85 g of bait. At the time mounds were dismantled, all showed signs of inattention: external cracking, delamination, and general external weathering. Mound repair and temperature profile data indicate that colony decline commenced much earlier than 19 wk and 14 wk, respectively, for trials 1 and 2, from as early as 4 wk onward. The ability of colonies to repair mound damage was impaired as early as 4 wk in some colonies, and mean internal mound temperatures in treated mounds began declining from 8 wk onward and clearly diverged from mean temperatures of untreated mounds thereafter. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

An experimental study on acute brain radiation injury: Dynamic changes in proton magnetic resonance spectroscopy and the correlation with histopathology

Energy Technology Data Exchange (ETDEWEB)

Li, Hui, E-mail: lihui@sysucc.org.cn [State Key Laboratory of Oncology in Southern China, Guangzhou (China); Medical Imaging and Minimally Invasive Interventional Center, Cancer Center, Sun Yat-sen University, Guangzhou (China); Li, Jian-peng, E-mail: lijp@sysucc.org.cn [Department of Radiology, Dongguan People' s Hospital, Dongguan City (China); Lin, Cheng-guang, E-mail: linchg@sysucc.org.cn [State Key Laboratory of Oncology in Southern China, Guangzhou (China); Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, Guangzhou (China); Liu, Xue-wen, E-mail: liuxw@sysucc.org.cn [State Key Laboratory of Oncology in Southern China, Guangzhou (China); Medical Imaging and Minimally Invasive Interventional Center, Cancer Center, Sun Yat-sen University, Guangzhou (China); Geng, Zhi-jun, E-mail: gengzhj@sysucc.org.cn [State Key Laboratory of Oncology in Southern China, Guangzhou (China); Medical Imaging and Minimally Invasive Interventional Center, Cancer Center, Sun Yat-sen University, Guangzhou (China); Mo, Yun-xian, E-mail: moyx@sysucc.org.cn [State Key Laboratory of Oncology in Southern China, Guangzhou (China); Medical Imaging and Minimally Invasive Interventional Center, Cancer Center, Sun Yat-sen University, Guangzhou (China); Zhang, Rong, E-mail: zhangr@sysucc.org.cn [State Key Laboratory of Oncology in Southern China, Guangzhou (China); Medical Imaging and Minimally Invasive Interventional Center, Cancer Center, Sun Yat-sen University, Guangzhou (China); Xie, Chuan-miao, E-mail: xchuanm@sysucc.org.cn [State Key Laboratory of Oncology in Southern China, Guangzhou (China); Medical Imaging and Minimally Invasive Interventional Center, Cancer Center, Sun Yat-sen University, Guangzhou (China)

2012-11-15

Purpose: To investigate the correlation between the alterations of single-voxel {sup 1}H MRS and the histopathological characteristics of radiation brain injury following radiation. Materials and methods: Twenty-seven rabbits were randomized into nine groups to receive radiation with a single dose of 25 Gy. The observation time points included a pre-radiation and 1, 2, 3, 4, 5, 6, 7, and 8 wk following radiation. Each treatment group underwent conventional MRI and single-voxel {sup 1}H MRS, N-acetyl aspartate (NAA), choline (Cho), and creatine (Cr) were observed over the region of interest, and the presence or absence of lactate (Lac) and lipid (Lip) was detected. Histological specimens of each group were obtained after image acquisition. Results: The values of Cho were significantly increased in the first 3 wk, and decreased over the following 5 wk after radiation. Levels of NAA showed a trend toward a decrease 5 wk after radiation. The levels of Cr were not changed between before and after radiation. The Cho/NAA metabolic ratio was significantly increased in weeks 6, 7, and 8 following irradiation, compared to pre-radiation values. Vascular and glial injury appeared on 2 wk after RT in the histology samples, until 4 wk after RT, necrosis of the oligodendrocytes, neuronal degeneration and demyelination could be observed. Conclusions: MRS is sensitive to detect metabolic changes following radiation, and can be used in the early diagnosis of radiation brain injury.

Neonatal changes in renal blood flow distribution in puppies

International Nuclear Information System (INIS)

Aschinberg, L.C.; Goldsmith, D.I.; Olbing, H.; Spitzer, A.; Edelmann, C.M. Jr.; Blaufox, M.D.

1975-01-01

The intrarenal distribution of blood flow was studied in 31 newborn mongrel puppies from 18 h to 70 days using xenon washout and krypton autoradiography. Mean renal blood flow increased from 0.39 +- 0.05 ml/g per min (SE) the 1st wk to 2.06 +- 0.12 ml/g per min at 6 wk. During the 1st wk of life the renal cortex was perfused homogeneously at 0.88 +- 0.19 ml/g min (SE) and accounted for 35 +- 4 percent of the renal blood flow. During the 2nd wk a narrow, rapidly perfused zone of outer cortex was identified which was perfused at 3.35 +- 0.26 ml/g per min, received 19.53 +- 5.05 percent of the total renal blood flow, and represented 15 +- 4 percent of the mass of the total cortex. The inner cortex and outer medulla at this time received 53.40 +- 4.12 percent of the flow at 1.07 +- 0.08 ml/g per min. Outer cortical flow increased with age reaching adult values by about 6 to 10 wk when the rapidly perfused area represented 40 +- 8 percent of the cortex. These changes are parallel to the results of previously reported studies with microspheres in newborn puppies and are compatible with the well-established maturational changes noted in neonates of several species. They represent the first gas-washout studies in animals during the first 6 wk of life

Generating Chimeric Mice by Using Embryos from Nonsuperovulated BALB/c Mice Compared with Superovulated BALB/c and Albino C57BL/6 Mice.

Science.gov (United States)

Esmail, Michael Y; Qi, Peimin; Connor, Aurora Burds; Fox, James G; García, Alexis

2016-01-01

The reliable generation of high-percentage chimeras from gene-targeted C57BL/6 embryonic stem cells has proven challenging, despite optimization of cell culture and microinjection techniques. To improve the efficiency of this procedure, we compared the generation of chimeras by using 3 different inbred, albino host, embryo-generating protocols: BALB/cAnNTac (BALB/c) donor mice superovulated at 4 wk of age, 12-wk-old BALB/c donor mice without superovulation, and C57BL/6NTac-Tyr(tm1Arte) (albino B6) mice superovulated at 4 wk of age. Key parameters measured included the average number of injectable embryos per donor, the percentage of live pups born from the total number of embryos transferred to recipients, and the number of chimeric pups with high embryonic-stem-cell contribution by coat color. Although albino B6 donors produced significantly more injectable embryos than did BALB/c donors, 12-wk-old BALB/c donor produced high-percentage (at least 70%) chimeras more than 2.5 times as often as did albino B6 mice and 20 times more efficiently than did 4-wk-old BALB/c donors. These findings clearly suggest that 12-wk-old BALB/c mice be used as blastocyst donors to reduce the number of mice used to generate each chimera, reduce the production of low-percentage chimeras, and maximize the generation of high-percentage chimeras from C57BL/6 embryonic stem cells.

Cardiovascular response to prescribed detraining among recreational athletes.

Science.gov (United States)

Pedlar, Charles R; Brown, Marcel G; Shave, Robert E; Otto, James M; Drane, Aimee; Michaud-Finch, Jennifer; Contursi, Miranda; Wasfy, Meagan M; Hutter, Adolph; Picard, Michael H; Lewis, Gregory D; Baggish, Aaron L

2018-04-01

Exercise-induced cardiac remodeling (EICR) and the attendant myocardial adaptations characteristic of the athlete's heart may regress during periods of exercise reduction or abstinence. The time course and mechanisms underlying this reverse remodeling, specifically the impact of concomitant plasma volume (PV) contraction on cardiac chamber size, remain incompletely understood. We therefore studied recreational runners ( n = 21, age 34 ± 7 yr; 48% male) who completed an 18-wk training program (~7 h/wk) culminating in the 2016 Boston Marathon after which total exercise exposure was confined to 1 h) for 8 wk. Cardiac structure and function, exercise capacity, and PV were assessed at peak fitness (10-14 days before) and at 4 wk and 8 wk postmarathon. Mixed linear modeling adjusting for age, sex, V̇o 2peak , and marathon finish time was used to compare data across time points. Physiological detraining was evidenced by serial reductions in treadmill performance. Two distinct phases of myocardial remodeling and hematological adaptation were observed. After 4 wk of detraining, there were significant reductions in PV (Δ -6.0%, P recreational runners and occurs with a distinct time course. Initial reductions in plasma volume and left ventricular (LV) mass, driven by reductions in wall thickness, are followed by contraction of the right ventricle. Consistent with data from competitive athletes, LV chamber volumes appear less responsive to detraining and may be a more permanent adaptation to sport.

Interactions between sire family and production environment (temperate vs. tropical) on performance and thermoregulation responses in growing pigs.

Science.gov (United States)

Rosé, R; Gilbert, H; Loyau, T; Giorgi, M; Billon, Y; Riquet, J; Renaudeau, D; Gourdine, J-L

2017-11-01

The aim of this study was to evaluate the effect of 2 climatic environments (temperate [TEMP] vs. tropical humid [TROP]) on production and thermoregulation traits in growing pigs. A backcross design involving Large White (LW; heat sensitive) and Creole (CR; heat tolerant) pigs was studied. The same 10 F LW × CR boars were mated with related LW sows in each environment. A total of 1,298 backcross pigs ( = 634 pigs from 11 batches for the TEMP environment and = 664 pigs from 12 batches for the TROP environment) were phenotyped on BW (every 15 d from wk 11 to 23 of age), voluntary feed intake (ADFI, from wk 11 to 23), backfat thickness (BFT; at wk 19 and 23), skin temperature (ST; at wk 19 and 23), and rectal temperature (RT; at wk 19, 21, and 23). The feed conversion ratio was computed for the whole test period (11 to 23 wk). The calculation of the temperature-humidity index showed an average difference of 2.4°C between the TEMP and TROP environments. The ADG and ADFI were higher in the TEMP environment than in the TROP environment (834 vs. 754 g/d and 2.20 vs. 1.80 kg/d, respectively; environment than in the TEMP environment (35.9 vs. 34.8°C for ST and 39.5 vs. 39.3°C for RT, respectively; environment interactions ( environment interaction and to detect QTL related to heat tolerance.

Age-related macular degeneration: Effects of a short-term intervention with an oleaginous kale extract--a pilot study.

Science.gov (United States)

Arnold, Christin; Jentsch, Susanne; Dawczynski, Jens; Böhm, Volker

2013-01-01

Age-related macular degeneration (AMD) is a multifactorial degenerative disease of the retina, which accounts for slowly progressive visual impairment in the elderly. An increased dietary intake of xanthophylls is suggested to be inversely related to the risk of macular disease. The present study was designed as a randomized, double-blind, placebo-controlled, parallel trial examining the influence of a short-term intervention with an oleaginous extract of Brassica oleracea var. sabellica L. (kale) on plasma xanthophyll concentrations and the optical density of the macular pigment xanthophylls (MPOD). Twenty patients with non-exudative AMD were recruited for a 10-wk study period (2-wk run-in, 4-wk intervention, 4-wk washout). All participants received 50 mL of a beverage containing either an oleaginous extract of kale (kale) or refined rapeseed oil (placebo). The verum product provides 10 mg lutein and 3 mg zeaxanthin per day. The concentrations of the xanthophylls in plasma and the MPOD increased significantly in the kale group after 4 wk of intervention. The successive washout period resulted in a significant decline of the values in plasma and macula. The values at the end of the study were still significantly higher than the initial values. Nevertheless, the improvements did not persist over 4 wk of washout. The distribution of the xanthophylls in the macula seems to be more dynamic than originally assumed. Copyright © 2013 Elsevier Inc. All rights reserved.

Effects of Intermittent Altitude Exposures on Acclimatization of 4,300 M

National Research Council Canada - National Science Library

Beidleman, Beth

2001-01-01

This study examined the effects of 3 wk of intermittent exposures (4 h/d, 5 d/wk) to 4,300 m altitude-equivalent, in combination with either passive sitting or exercise training, on the process of altitude acclimatization...

Effects of continuous ivermectin treatment from birth to puberty on growth and reproduction in dairy heifers.

Science.gov (United States)

Mejía, M; Gonzalez-Iglesias, A; Díaz-Torga, G S; Villafañe, P; Formía, N; Libertun, C; Becú-Villalobos, D; Lacau-Mengido, I M

1999-06-01

The effect of continuous ivermectin treatment from birth to puberty on growth and reproductive performance was studied in Holstein heifer calves grown on pastures in comparison to naturally nematode-infected, untreated animals. Ivermectin effectively abated the presence of nematode eggs in feces. Eggs per gram (EPG) in parasitized animals increased rapidly from wk 12 to 18 of age and then decreased. Animals treated with ivermectin grew faster than untreated ones, and differences in body weight became significant at 6 wk of life, even before eggs appeared in the feces of either treatment group. Ivermectin-treated heifers reached puberty 3 wk earlier than infected ones as assessed with serum progesterone concentrations (ivermectin, 30.4 +/- .8 vs untreated, 33.7 +/- 1.3 wk of age). This delay was not directly related to body weight. In addition, pelvic area at 39 wk and at 15 mo of age was increased in treated heifers (8 and 11%, respectively) compared with parasitized animals. No differences in the wither heights were observed. We conclude that ivermectin treatment in dairy heifers may increase growth rate during development, advance the onset of ovarian function, and positively affect yearling pelvic area.

Effect of fenbendazole on an autoimmune mouse model.

Science.gov (United States)

Cray, Carolyn; Watson, Toshiba; Zaias, Julia; Altman, Norman H

2013-01-01

Fenbendazole is an anthelmintic drug widely used to treat and prevent pinworm infection in laboratory rodents. Data regarding possible side effects of fenbendazole on the immune system are conflicting, potentially due to the design of treatment protocols. The purpose of the current study was to determine the effects of 2 fenbendazole therapeutic regimens (continuous for 5 wk and alternating weeks [that is, 1 wk on, 1 wk off] for 9 wk) on the development of autoimmune disease in (NZB × NZW)F1 mice. No significant differences in survival curves or weight were observed between the treatment groups and cohort mice receiving nonmedicated feed. At the termination of the experiment, there were no differences in tissue pathology. Hematocrit decreased and BUN increased over time in all groups, but no significant differences were present between groups. After the cessation of treatment, mice fed the medicated diet continuously for 5 wk showed an increase in antiDNA antibody. Although this difference was significant, it did not affect survival curves or disease-related tissue or blood changes. These data indicate that common protocols of fenbendazole treatment do not alter the progression of autoimmune disease in (NZB × NZW)F1 mice.

Body morphometric development during growth and maturity of coloured dwarf rabbits available in the Italian market

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Antonella Dalle Zotte

2013-12-01

Full Text Available This study was designed to measure the live performance of “coloured dwarf” rabbits available in the Italian market during both the growing and adult maintenance periods to provide new insights on this breed, with specific regard to the gender effect. A further objective was to identify the morphometric characteristics of the selected population and compare them to the standard breeding requirements. Body weight (BW and body morphometric development were monitored in 145 “coloured dwarf” rabbits (80 males and 65 females during 2 different periods: 7-21 wk of age (growth and 28-45 wk of age (adultmaintenance. The animals were housed in individual cages and fed ad libitum with a commercial pelleted diet. Individual BW and feed consumption were measured twice a week to determine weight gain, feed intake and feed conversion index, whereas the health status was monitored daily. At 20 and 45 wk of age, the skin fold width and body measurements were taken on each rabbit at predefined anatomical points. The body measurements included: body length (BL, ear length (EL, head height (HH, shoulder width (SW, rump width (RW, forehead width (FHW, head width (HW, tibia width (TW, thoracic circumference (TC, abdominal circumference (AC and 3 body indices: RW/BL, TC/BL, AC/BL. At 20 wk of age, the body weight of females (F was heavier than that of males (M (F: 1.630 vs. M: 1.542 g, P<0.001 and this significant difference was also maintained during the maintenance phase of the study (F: 1.953 vs. M: 1.850 g; P<0.001 at 45 wk. Interestingly, up to 20 wk of age average feed intake was higher and weight gain more rapid in F than M, whereas from 40 wk of age onwards the situation was reversed, as M registered a higher average feed intake (P<0.05. At 45 wk of age, the skin fold width was thicker in M than in F (M: 4.28 vs. F: 3.56 mm; P<0.001. All body measurements were affected by age and almost all of them also by gender, with the exception of BL, EL, FHW and

Competition during the milk-feeding stage influences the development of feeding behavior of pair-housed dairy calves.

Science.gov (United States)

Miller-Cushon, E K; Bergeron, R; Leslie, K E; Mason, G J; DeVries, T J

2014-10-01

This study investigated how the feeding behavior of pair-housed calves develops in response to reduced teat and feed place availability. Twenty Holstein bull calves were pair housed and provided with milk replacer (MR) and grain concentrate ad libitum via either (1) 1 teat and feed bucket/pen, such that calves could not feed simultaneously [competitive feeding (CF)] or (2) 2 teats and feed buckets/pen [noncompetitive feeding (NCF)]. The calves were weaned during wk 7 of life by incrementally diluting the MR. Postweaning, all pens were managed identically and offered a complete pelleted diet ad libitum via 2 feed buckets/pen (NCF) in period 1 (wk 8 and 9) and period 3 (wk 12 and 13) and exposed to a competitive challenge with CF in period 2 (wk 10 and 11). Feeding times and competitive interactions were recorded from video for 3 d/wk in wk 2, 4, and 6 and 2 d/wk in wk 8 to 13. Meal criteria were used to calculate daily meal frequency, meal time, and synchronized meal time (the percentage of meal time when calves within the pen were engaged in simultaneous meals). Milk replacer intake was subject to a treatment × week interaction, with calves in CF pens having lower MR intake (wk 2: 8.3 vs. 10.0 L/calf per day for CF vs. NCF), but compensating by increasing intake to a greater extent over time (wk 4-5: 13.3 vs. 11.7 L/d for CF vs. NCF). Corresponding to MR intake, meal frequencies and feeding times evolved differently over this period, increasing in CF pens and decreasing in NCF pens (wk 2: 5.8 vs. 11.1 and wk 4-6: 6.2 vs. 5.1 meals/d for CF vs. NCF). Calves in CF pens also spent less time engaged in synchronized meals (28 vs. 51% of meal time; standard error=7.1) and displaced each other 5 times more frequently during synchronized eating. Postweaning, calves in previously CF pens maintained 5 times greater displacement frequencies and had fewer overlapping meals than calves in previously NCF pens (34.5 vs. 40.7% of meals, respectively). Postweaning, when calves

Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems

Science.gov (United States)

More, Swati S.; Itsara, Melissa; Yang, Xiaodong; Geier, Ethan G.; Tadano, Michelle K.; Seo, Youngho; VanBrocklin, Henry F.; Weiss, William A.; Mueller, Sabine; Haas-Kogan, Daphne A.; DuBois, Steven G.; Matthay, Katherine K.; Giacomini, Kathleen M.

2011-01-01

Purpose Histone deacetylase (HDAC) inhibition causes transcriptional activation or repression of several genes that in turn can influence the biodistribution of other chemotherapeutic agents. Here, we hypothesize that the combination of vorinostat, a HDAC inhibitor, with 131I-metaiodobenzylguanidine (MIBG) would lead to preferential accumulation of the latter in neuroblastoma (NB) tumors via increased expression of the human norepinephrine transporter (NET). Experimental Design In vitro and in vivo experiments examined the effect of vorinostat on the expression of NET, an uptake transporter for 131I-MIBG. Human NB cell lines (Kelly and SH-SY-5Y) and NB1691luc mouse xenografts were employed. The upregulated NET protein was characterized for its effect on 123I-MIBG biodistribution. Results Preincubation of NB cell lines, Kelly and SH-SY-5Y, with vorinostat caused dose-dependent increases in NET mRNA and protein levels. Accompanying this was a corresponding dose-dependent increase in MIBG uptake in NB cell lines. Four-fold and 2.5 fold increases were observed in Kelly and SH-SY-5Y cells, respectively, pre-treated with vorinostat in comparison to untreated cells. Similarly, NB xenografts, created by intravenous tail vein injection of NB1691-luc, and harvested from nude mice livers treated with vorinostat (150 mg/kg i.p.) showed substantial increases in NET protein expression. Maximal effect of vorinostat pretreatment in NB xenografts on 123I-MIBG biodistribution was observed in tumors that exhibited enhanced uptake in vorinostat treated (0.062 ± 0.011 μCi/(mg tissue-dose injected)) versus untreated mice (0.022 ± 0.003 μCi/(mg tissue-dose injected); p vorinostat treatment can enhance NB therapy with 131I-MIBG. PMID:21421857

PENGARUH SUKU BUNGA DEPOSITO DAN LAYANAN ATM TERHADAP EKUITAS MEREK SERTA DAMPAKNYA TERHADAP KEPUTUSAN KONSUMEN UNTUK MENJADI NASABAH DI KANTOR CABANG UTAMA PT BANK JABAR DAN BANTEN TBK

Directory of Open Access Journals (Sweden)

Donni Juni Priansa

2016-03-01

Full Text Available Abstract - Banks are business entities that raise funds from the public and channel them to the public in the form of credit or other forms. Associated with the function of the banking, deposit and ATM services are two important things that are often considered by consumers. This study aims to analyze the influence of deposits interest rates and ATM services to brand equity, as well as the influence of deposits interest rates, ATM services, and brand equity on consumer's decision to become a customer. This study uses descriptive and explanatory survey, with primary data obtained from questionnaires. The population of this research is consumers that’s become customers at PT Bank Jabar Banten Tbk Branch Office and utilizing deposits and ATM services. The unit of analysis in the study were 40 samples were obtained by using the formula Slovin, while sampling technique used was simple random sampling. Data were analyzed using path analysis with SPSS 20.00. The results showed that the deposits interest rates and ATM services has positive dan significant effect on brand equity. The study also found that deposits interest rates, ATM services, and brand equity has a positive and significant effect on the consumer's decision to become a customer at PT Bank Jabar Banten Tbk Main Branches.   Keyword: Deposits Interest Rates, ATM Services, and Consumer's Decision     Abstrak - Bank adalah badan usaha yang menghimpun dana dari masyarakat dan menyalurkannya kembali dalam bentuk kredit dan atau bentuk-bentuk lainnya. Terkait dengan fungsi perbankan tersebut, suku bunga deposito dan layanan ATM merupakan dua hal penting yang sering dipertimbangkan oleh konsumen untuk menjadi nasabah bank. Penelitian ini bertujuan untuk menganalisis pengaruh suku bunga deposito dan layanan ATM terhadap ekuitas merek, juga pengaruh suku bunga deposito, layanan ATM, dan ekuitas merek terhadap keputusan konsumen untuk menjadi nasabah. Penelitian ini menggunakan metode

The Critical Role of Stewardship in Fund Raising: The Coaches vs. Cancer Campaign.

Science.gov (United States)

Worley, Debra A.; Little, Jennifer K.

2002-01-01

Examines the critical role of stewardship in the process of fund raising. Uses the Coaches vs. Cancer campaign to illustrate the limitations of the public relations ROPE (research, objectives, planning, and evaluation) model in explaining fund raising success, and supports K.S. Kelly's contention that addition of a fifth step to the model, the…

Jordanian Social Studies Teachers' Perceptions of Competency Needed for Implementing Technology in the Classroom

Science.gov (United States)

Al Bataineh, Mohammad; Anderson, Sharon

2015-01-01

This study used a cross-sectional, ten-point Likert-type scale survey design, to examine the perception of Jordanian seventh to twelfth-grade social studies teachers of the competency needed for technology implementation in their classrooms. The instrument for this study was a modified version of a survey developed by Kelly (2003) called the…

15. juunini on tarbekunstimuuseumi galeriis...

Index Scriptorium Estoniae

2003-01-01

Ühisnäitusel "Ruum ei ole tühi" osalevad tekstiilikunstnikud Eva-Liisa Kriis, Monika Järg, Liisa Kallam, Liisa Tomasberg, Tarmo Mäesalu, Keret Altpere, Ülle Saatmäe, Annike Laigo, tootedisainerid Raul Erdel, Kelly Kert, arhitekt Urmas Luure, sisearhitekt Terje Kallast, fotograaf Pelle Kalmo, graafik Mari-Liis Laanemaa, muusik Taavi Laatsit

analysis of the probability of channel satisfactory state in p2p live

African Journals Online (AJOL)

userpc

churn and bits flow was modelled as fluid flow. The applicability of the theory of probability was deduced from Kelly (1991). Section II of the paper provides the model of. P2P live streaming systems taking into account peer behaviour and expression was obtained for the computation of the probability of channel- satisfactory ...

The Growing Racial and Ethnic Divide in U.S. Marriage Patterns

Science.gov (United States)

Raley, R. Kelly; Sweeney, Megan M.; Wondra, Danielle

2015-01-01

The United States shows striking racial and ethnic differences in marriage patterns. Compared to both white and Hispanic women, black women marry later in life, are less likely to marry at all, and have higher rates of marital instability. Kelly Raley, Megan Sweeney, and Danielle Wondra begin by reviewing common explanations for these differences,…

77 FR 49384 - FMCSA Policy on the Timeliness of New Entrant Corrective Action Submissions

Science.gov (United States)

2012-08-16

... 15 days of the date of a new entrant safety audit failure notice or within 10 days of the date of an... 20, 2012 for safety audit failure notices. FOR FURTHER INFORMATION CONTACT: Thomas Kelly, Office of... FMCSA's New Entrant Safety Assurance Program, 49 CFR Part 385, subpart D, applies to new entrant motor...

Hydrological principles for sustainable management of forest ecosystems

Science.gov (United States)

Irena F. Creed; Gabor Z. Sass; Jim M. Buttle; Julia A. Jones

2011-01-01

Forested landscapes around the world are changing as a result of human activities, including forest management, fire suppression, mountaintop mining, conversion of natural forests to plantations, and climate change (Brockerhoff et al., 2008; Cyr et al., 2009; Johnston et al., 2010; Miller et al., 2009; Kelly et al., 2010; Palmer et al., 2010). Forests...

Emblem for the first manned Skylab mission

Science.gov (United States)

1972-01-01

This is the emblem for the first manned Skylab mission. It wil be a mission of up to 28 days. The patch, designed by artist Kelly Freas, shows the Skylab silhouetted against the earth's globe, which in turn is eclipsing the Sun - showing the brilliant signet-ring pattern of the instant before total eclipse.

Effects of dry period length and concentrate protein content in late lactation on body condition score change and subsequent lactation performance of thin high genetic merit dairy cows.

Science.gov (United States)

Dale, A J; Purcell, P J; Wylie, A R G; Gordon, A W; Ferris, C P

2017-03-01

Improving body condition score of thin cows in late lactation is necessary, because cows that are thin at drying off exhibit decreased fertility postpartum and are at increased risk of disease and of being culled in the subsequent lactation. Offering a diet low in crude protein (CP) content in late lactation may help to improve body condition score (BCS) at drying off, whereas imposing an extended dry period (EDP) has been advocated as another way to increase BCS at calving. To test these hypotheses, 65 thin cows (mean BCS 2.25 at 14 wk precalving) were managed on 1 of 3 treatments between 13 and 9 wk prepartum: normal protein control {NP; grass silage + 5 kg/d of a normal protein concentrate [228 g of CP/kg of dry matter (DM)]}, low protein [LP; grass silage + 5 kg/d of a low-protein concentrate (153 g of CP/kg of DM)], or EDP (cows dried off at 13 wk precalving and offered a grass silage-only diet). Both NP and LP cows were dried off at wk 8 prepartum, after which all cows were offered a grass silage-only diet until calving. After calving, all cows were offered a common diet (supplying 11.1 kg of concentrate DM/cow per day) for 19 wk. Between 13 and 9 wk prepartum, LP cows had lower DM intake, milk yield, and body weight than NP cows. Whereas EDP cows had lower serum β-hydroxybutyrate and fatty acid concentrations than those of NP cows, BCS at wk 9 prepartum did not differ between treatments. Cows on the LP treatment continued to have lower DMI and BW than those of NP and EDP cows between 8 wk prepartum and calving, but only EDP cows had a higher BCS at calving. Treatment did not affect calving difficulty score or calf birth weight. Although all cows were offered a common diet postpartum, cows on the LP treatment had lower DM intake and milk fat + plus protein yield than cows on any other treatment during the 19-wk period postpartum, but we found no differences in any postpartum indicator of body tissue reserves. The treatments imposed from wk 13 to 9 prepartum

Parametric Adaptive Radar Detector with Enhanced Mismatched Signals Rejection Capabilities

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Liu Bin

2010-01-01

Full Text Available We consider the problem of adaptive signal detection in the presence of Gaussian noise with unknown covariance matrix. We propose a parametric radar detector by introducing a design parameter to trade off the target sensitivity with sidelobes energy rejection. The resulting detector merges the statistics of Kelly's GLRT and of the Rao test and so covers Kelly's GLRT and the Rao test as special cases. Both invariance properties and constant false alarm rate (CFAR behavior for this detector are studied. At the analysis stage, the performance of the new receiver is assessed and compared with several traditional adaptive detectors. The results highlight better rejection capabilities of this proposed detector for mismatched signals. Further, we develop two two-stage detectors, one of which consists of an adaptive matched filter (AMF followed by the aforementioned detector, and the other is obtained by cascading a GLRT-based Subspace Detector (SD and the proposed adaptive detector. We show that the former two-stage detector outperforms traditional two-stage detectors in terms of selectivity, and the latter yields more robustness.

The study of topics of Astronomy in Physics teaching that addresses the significant learning

Science.gov (United States)

Santos Neta, M. L.; Voelzke, M. R.

2017-12-01

In this work are discussed the results of the case study on the oceanic tides for which it was used didactic sequences, based on the Cycle of Experience of George Kelly (Kelly 1963), applied in four groups of the first year of the integral medium teaching. The data obtained in two same tests - Pre and Post-Test - before and after the application of the didactic sequences, as well as the verification of the significant learning analysed as for the conditions of the previous knowledge considering authors Boczko (1984), Horvath (2008) and Kepler & Saraiva (2013). Also the values were analysed obtained the Post-Test II applied to the long period. The results reveal that the worked groups presented previous knowledge in conditions adapted for the understanding of the event, as well as, for they be used in the situation-problem resolution that demands the understanding. Verify also that the idea of the didactic sequence can be used as tool in the relationship teaching-learning addressed to the significant learning.

The evolution model of Uppsala in light of the complex adaptive systems approach

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Rennaly Alves da Silva

2013-11-01

Full Text Available The behavioral approach to the internationalization of companies explains that the movements toward external markets occur in accordance with the increasing commitment of resources to mitigate the effects of uncertainty and reduce the perception of risk. Evidence indicates that the theories and practices developed in the domestic market may not be able to explain the reality of companies that operate in international markets. Thus, the Paradigm of Complexity presents itself as a comprehensive alternative to realize the relationships within organizations and markets. Accordingly, the aim of this theoretical paper is to analyze the evolution of the Uppsala Model between years 1975 and 2010 with the understanding of the companies in the process of internationalization as Complex Adaptive Systems, in accordance with the Model Kelly and Allison (1998. Four propositions are presented that show the links between the approaches. The most surprising is the perception that the conceptual evolution of the Uppsala Model seems to accompany the evolution of complexity levels, presented in Model Kelly and Allison.

Evaluation of the addition of organic acids in the feed and/or water for broilers and the subsequent recovery of Salmonella Typhimurium from litter and ceca.

Science.gov (United States)

Bourassa, D V; Wilson, K M; Ritz, C R; Kiepper, B K; Buhr, R J

2018-01-01

Three separate broiler Salmonella Typhimurium challenge experiments were conducted evaluating efficacy of formic and propionic acid feed supplements to suppress environmental and cecal Salmonella Typhimurium prevalence. In experiment 1, broilers were provided feed with 1 kg/ton formic acid or 5 kg/ton propionic acid feed additives or a basal control diet. At the day of placement, half of the pens were inoculated with seeder chicks orally challenged with a marker strain of Salmonella Typhimurium and to yield challenged and adjacent nonchallenged pens. No differences in weekly litter samples or cecal Salmonella prevalence at 3 or 6 wk among feeding treatments were detected. In experiment 2, treatments were: 2 kg/ton propionic acid in feed, 1.0 mL/L formic acid in water, both propionic acid in feed and formic acid in water, and a basal control. Every pen was challenged with seeder chicks inoculated with Salmonella Typhimurium. By 6 wk all pens maintained detectable litter Salmonella, and broilers provided both propionic acid in feed and formic acid in water had the lowest cecal recovery (35%), compared to the control (60%). In experiment 3, treatments were: formic acid at 4 or 6 kg/ton from wk 0 to 6 or for only the last wk, propionic acid at 5 or 10 kg/ton for only the last wk, and a basal control. Each pen was challenged with Salmonella Typhimurium inoculated seeder chicks. By 6 wk, broilers fed formic acid (4 kg/ton) for the entire growout had no Salmonella-positive ceca (0/30). All treatments that provided acid supplemented feed for only the last wk had 3-13% Salmonella-positive ceca. These experiments indicate that adding formic acid to broiler feed appears to prevent Salmonella colonization from challenge pens entering into the adjacent nonchallenge pens. Feeding formic acid (4 kg/ton) for 6 wk resulted in no recovery of Salmonella from ceca compared to the control prevalence of 17%. Published by Oxford University Press on behalf of Poultry Science

Transmission of Salmonella to broilers by contaminated larval and adult lesser mealworms, Alphitobius diaperinus (Coleoptera: Tenebrionidae).

Science.gov (United States)

Roche, A J; Cox, N A; Richardson, L J; Buhr, R J; Cason, J A; Fairchild, B D; Hinkle, N C

2009-01-01

The ability of the lesser mealworm, Alphitobius diaperinus (Panzer), commonly known as the darkling beetle, to transmit marker Salmonella Typhimurium to day-of-hatch broiler chicks was evaluated, as well as the spread to nonchallenged pen mates. In trial 1, day-of-hatch chicks were orally gavaged with 4 larval or 4 adult beetles that had been exposed to marker Salmonella-inoculated feed for 72 h. In addition, chicks were gavaged with the marker Salmonella in saline solution. These chicks were then placed into pens to serve as challenged broilers. In trial 2, all pens received 2 challenged chicks that were gavaged with larvae or beetles that had been exposed to marker Salmonella-inoculated feed for 24 h and then removed from the inoculated feed for a period of 7 d. At 3 wk of age, cecal samples from the marker Salmonella-challenged broilers and from 5 pen mates in trial 1, or 10 pen mates in trial 2, were evaluated for the presence of the marker Salmonella in their ceca, and at 6 wk of age, all remaining pen mates were sampled. To monitor the presence of the marker Salmonella within pens, stepped-on drag swab litter samples were taken weekly. For the Salmonella-saline pens, 29 to 33% of the broilers that had been challenged and 10 to 55% of the pen mates were positive at 3 wk of age, and only 2 to 6% had positive ceca at 6 wk. For the pens challenged with adult beetles, 0 to 57% of the challenged broilers and 20 to 40% of the pen mates had positive ceca at 3 wk, and 4 to 7% were positive at 6 wk. The pens challenged with larvae had the greatest percentage of marker Salmonella-positive broilers; 25 to 33% of the challenged broilers and 45 to 58% of pen mates were positive at 3 wk, and 11 to 27% were positive at 6 wk. These results demonstrated that ingestion of larval or adult beetles contaminated with a marker Salmonella could be a significant vector for transmission to broilers.

Posterior Thalamic Nucleus Modulation of Tactile Stimuli Processing in Rat Motor and Primary Somatosensory Cortices

Directory of Open Access Journals (Sweden)

Diana Casas-Torremocha

2017-09-01

Full Text Available Rodents move rhythmically their facial whiskers and compute differences between signals predicted and those resulting from the movement to infer information about objects near their head. These computations are carried out by a large network of forebrain structures that includes the thalamus and the primary somatosensory (S1BF and motor (M1wk cortices. Spatially and temporally precise mechanorreceptive whisker information reaches the S1BF cortex via the ventroposterior medial thalamic nucleus (VPM. Other whisker-related information may reach both M1wk and S1BF via the axons from the posterior thalamic nucleus (Po. However, Po axons may convey, in addition to direct sensory signals, the dynamic output of computations between whisker signals and descending motor commands. It has been proposed that this input may be relevant for adjusting cortical responses to predicted vs. unpredicted whisker signals, but the effects of Po input on M1wk and S1BF function have not been directly tested or compared in vivo. Here, using electrophysiology, optogenetics and pharmacological tools, we compared in adult rats M1wk and S1BF in vivo responses in the whisker areas of the motor and primary somatosensory cortices to passive multi-whisker deflection, their dependence on Po activity, and their changes after a brief intense activation of Po axons. We report that the latencies of the first component of tactile-evoked local field potentials in M1wk and S1BF are similar. The evoked potentials decrease markedly in M1wk, but not in S1BF, by injection in Po of the GABAA agonist muscimol. A brief high-frequency electrical stimulation of Po decreases the responsivity of M1wk and S1BF cells to subsequent whisker stimulation. This effect is prevented by the local application of omega-agatoxin, suggesting that it may in part depend on GABA release by fast-spiking parvalbumin (PV-expressing cortical interneurons. Local optogenetic activation of Po synapses in different

Prevention of post weaning diarrhoea by a Saccharomyces cerevisiae-derived product based on whole yeast

DEFF Research Database (Denmark)

Jensen, K. H.; Damgaard, B. M.; Andresen, Lars Ole

2013-01-01

and their litters were randomly allocated to three treatment groups: PSP (1.5 g/kg of YD to the sows’ feed from 1 wk before expected farrowing to weaning; 3 g/kg or 2 g/kg of YD added to the piglets’ creep feed from 2 wk of age until 2 wk post weaning (PW) and from wk 2 to 5 PW, respectively); PP (YD added......-challenged piglets (P=0.030). In E. coli-challenged piglets faecal shedding of haemolytic E. coli was lower in PP than in C piglets (P=0.026). In placebo piglets the latency time to first observation of PWD was longer in PP than in PSP and C piglets (P=0.048 and P=0.017, respectively). The specific antibody titre...... to 5 PW (Plow pathogenic E. coli load, but may improve the G:F compared to no YD supplementation....

Inducible protein-10 as a predictive marker of antiviral hepatitis C treatment

DEFF Research Database (Denmark)

Neesgaard, Bastian; Ruhwald, Morten; Weis, Nina

2017-01-01

AIM: To investigate interferon-γ-inducible protein-10's (IP-10) potential to anticipate rapid (RVR)- and sustained virological responses (SVR) to chronic hepatitis C (CHC) treatment. METHODS: We included case series examining RVR or SVR in relation to 24 or 48 wk treatment for CHC, in patients...... treatment free for at least six months, with genotype 1 or 4, and in relation to 24 wk treatment for genotype 2 and 3, with pegylated interferon in combination with ribavirin. Patients had to have both a baseline IP-10 level as well as a hepatitis C virus (HCV)-RNA determination 4 wk after treatment...... initiation or 24 wk after end of treatment. Studies including patients with liver diseases other than CHC, human immunodeficiency virus-infection, treatment with immunosuppresents or cytostatica, alcohol dependency or active intravenous drug-use were excluded. We found 81 articles by searching the MEDLINE...

Oxidative stress induced in PCB 126-exposed northern leopard frogs, Rana pipiens

Science.gov (United States)

Huang, Y.-W.; Hoffman, D.J.; Karasov, W.H.

2007-01-01

Northern leopard frogs Rana pipiens exposed to PCB 126 (3,3',4,4',5-pentachlorobiphenyl) were examined for hepatic oxidative stress. In a dose-response study, northern leopard frogs were injected intraperitoneally with either PCB 126 in corn oil (0.2, 0.7, 2.3, or 7.8 mg/kg body weight) or corn oil alone. In a time-course study, frogs received 7.8 mg/kg or corn oil alone, and were examined at 1, 2, 3, and 4 wk after dosing. Hepatic concentrations of reduced glutathione (GSH), thiobarbituric acid-reactive substances (TBARS), and total sulfhydryls (total SH), as well as activities of glutathione peroxidase (GSH-P), GSSG reductase (GSSG-R), glucose-6-phosphate dehydrogenase (G-6-PDH), and glutathione S-transferase (GSH-S-T) were measured. In the dose-response experiment, few effects were apparent 1 wk after dosing. In the time-course experiment, significant changes were observed in the 7.8-mg/kg group at 2 wk or more posttreatment. Hepatic concentrations of GSH and TBARS were higher than in corresponding controls at wk 3 and 4; the activities of GSSG-R and GSH-S-T were higher than in controls at wk 2 and 4; and the activity of G-6-PDH was increased at wk 2 and 4. These data collectively indicate that altered glutathione metabolism and oxidative stress occurred and were indicative of both toxicity and induction of protective mechanisms in frogs exposed to PCB. A similar delay in response was reported in fish and may relate to lower metabolic rate and physiological reactions in ectothermic vertebrates

Oxidative stress induced in PCB 126-exposed northern leopard frogs, Rana pipiens.

Science.gov (United States)

Huang, Yue-wern; Hoffman, David J; Karasov, William H

2007-04-15

Northern leopard frogs Rana pipiens exposed to PCB 126 (3,3',4,4',5-pentachlorobiphenyl) were examined for hepatic oxidative stress. In a dose-response study, northern leopard frogs were injected intraperitoneally with either PCB 126 in corn oil (0.2, 0.7, 2.3, or 7.8 mg/kg body weight) or corn oil alone. In a time-course study, frogs received 7.8 mg/kg or corn oil alone, and were examined at 1, 2, 3, and 4 wk after dosing. Hepatic concentrations of reduced glutathione (GSH), thiobarbituric acid-reactive substances (TBARS), and total sulfhydryls (total SH), as well as activities of glutathione peroxidase (GSH-P), GSSG reductase (GSSG-R), glucose-6-phosphate dehydrogenase (G-6-PDH), and glutathione S-transferase (GSH-S-T) were measured. In the dose-response experiment, few effects were apparent 1 wk after dosing. In the time-course experiment, significant changes were observed in the 7.8-mg/kg group at 2 wk or more posttreatment. Hepatic concentrations of GSH and TBARS were higher than in corresponding controls at wk 3 and 4; the activities of GSSG-R and GSH-S-T were higher than in controls at wk 2 and 4; and the activity of G-6-PDH was increased at wk 2 and 4. These data collectively indicate that altered glutathione metabolism and oxidative stress occurred and were indicative of both toxicity and induction of protective mechanisms in frogs exposed to PCB. A similar delay in response was reported in fish and may relate to lower metabolic rate and physiological reactions in ectothermic vertebrates.

Genetic merit for fertility traits in Holstein cows: IV. Transition period, uterine health, and resumption of cyclicity.

Science.gov (United States)

Moore, S G; Fair, T; Lonergan, P; Butler, S T

2014-05-01

The objective of this study was to monitor the dry matter intake (DMI), metabolic status, uterine health, and resumption of cyclicity in cows with similar genetic merit for milk production traits but with either good (Fert+) or poor genetic merit (Fert-) for fertility traits. Twenty-six cows were enrolled in the study and data are reported for 15 Fert+ and 10 Fert- cows that completed the study. All cows received a total mixed ration diet during early lactation and were turned out to pasture in late spring. Dry matter intake was recorded daily from wk -2 to 5 relative to parturition. Blood metabolites and metabolic hormones were measured from wk -2 to 8 relative to parturition. Milk production, body condition score, and body weight until wk 35 of lactation are reported. To monitor uterine health, vaginal mucus was scored weekly on a scale of 0 (no pus) to 3 (≥ 50% pus) from parturition to wk 8 and uterine polymorphonuclear neutrophil count was measured at wk 3 and 6 postpartum. Prepartum DMI was similar between genotypes, but Fert+ cows had significantly greater DMI than Fert- cows (19.7 vs. 16.8 kg of dry matter/d) during the postpartum period. Energy balance at wk 1 was significantly greater in Fert+ cows than in Fert- cows [2.3 vs. -1.12 unité fourragère lait (UFL)/d]. The Fert+ cows had significantly greater daily milk solids production (1.89 vs. 1.74 kg/d) and tended to have greater daily milk yield (24.2 vs. 22.3 kg/d). The Fert+ cows had significantly greater mean circulating insulin-like growth factor-I (102.62 vs. 56.85 ng/mL) and tended to have greater mean circulating insulin (3.25 vs. 2.62 μIU/mL) compared with Fert- cows from wk -2 to 8 relative to parturition. Mean circulating glucose (3.40 vs. 3.01 mmol/L) concentrations were significantly greater in Fert+ cows compared with Fert- cows from wk -2 to 3 relative to parturition. The Fert+ cows maintained significantly greater mean body condition score throughout lactation compared with Fert- cows

Cooperative advanced-generation breeding and testing of coastal Douglas-fir and western hemlock—strategy and implementation.

Science.gov (United States)

K. J.S. Jayawickrama; G.R. Johnson; T. Ye

2005-01-01

As in many temperate regions of the world, forest tree improvement got underway in the Pacific Northwest of the USA in the 1950s, with a number of companies and agencies starting independent tree improvement programs. Booth-Kelly Lumber Co., Crown Zellerbach Corp., the Industrial Forestry Association, Port Blakely Mill Co., Simpson Timber Co., Timber Service Co., the...

Visual Sharpness Contingency in Recognition Memory for Orientation: Mnemonic Illusion Suppressed by Sensory Signature

Science.gov (United States)

Martin, Maryanne; Jones, Gregory V.

2006-01-01

A striking finding about human memory is that people's level of accuracy in remembering the orientation of heads on coins is often not simply at the chance level but significantly below it. However, S. W. Kelly, A. M. Burton, T. Kato, and S. Akamatsu (2001) reported that this is not so when two-alternative forced-choice visual recognition is…

Carrots, Sticks, and the Bully Pulpit: Lessons from a Half-Century of Federal Efforts to Improve America's Schools

Science.gov (United States)

Hess, Frederick M., Ed.; Kelly, Andrew P., Ed.

2012-01-01

This timely book brings together a remarkable group of authors who examine the federal role in education policy and reform during the past fifty years. As Frederick M. Hess and Andrew P. Kelly note in their introduction, the book represents a determined effort to move beyond familiar and predictable debates and instead to focus on a number of…

Browse Title Index

African Journals Online (AJOL)

Items 1 - 50 of 59 ... Vol 62 (2013), Cape Town's central city development: A strategy of partnership and inclusion, Abstract PDF. A Fleming, B Makalima-Ngewana. Vol 66 (2015), Compiling a land audit in ... C Green, G Mans, P Schmitz, D McKelly, M te Water. Vol 60 (2012), Planning innovation for better urban communities in ...

77 FR 36041 - San Antonio Central Railroad, L.L.C.-Lease Exemption-Port Authority of San Antonio

Science.gov (United States)

2012-06-15

... control of SAC upon SAC becoming a Class III rail carrier. As a result of this transaction, SAC will provide common carrier rail service over the rail lines owned by the Port in the East Kelly Railport (the... and operate approximately four miles of rail line owned by the Port Authority of San Antonio (the Port...

The Future Online: Instructional Communication Scholars Taking the Lead. Forum: The Future of Instructional Communication

Science.gov (United States)

Chatham-Carpenter, April

2017-01-01

As students begin using more virtual and augmented reality tools for education and entertainment, they may come to expect instructors to use similar types of technology in their teaching (Kelly, 2016). Instructors may choose to employ this type of technology in the future, to create more of a real-life feel in the online classroom. The effects of…

Responses of Forest Ecosystems to Changing Sulfur Inputs

Science.gov (United States)

Dale W. Johnson; Myron J. Mitchell

1998-01-01

There was little information on sulfur (S) cycling in forests compared with that of other nutrients (especially N) until the past two decades. Interest in S nutrition and cycling in forests was heightened with the discovery of deficiencies in some unpolluted regions (Kelly and Lambert, 1972; Humphreys et al., 1975; Turner et al., 1977, 1980) and excesses associated...

CERN celebrated the first year in space for the Alpha Magnetic Spectrometer (AMS) with a visit from the crew of the shuttle mission, STS-134, who successfully delivered AMS to the International Space Station (ISS) last year.

CERN Multimedia

Laurent Egli

2012-01-01

During the celebrations at CERN, the astronauts unveiled a commemorative plaque on the lawn outside the POCC to mark the occasion and later gave a public lecture at CERN. Picture 28 : STS-134 astronauts (left to right) Andrew Feustel, Gregory Chamitoff, Gregory Johnson, Michael Fincke and Mark Kelly in the AMS Payload Operations Centre at CERN.

A Chance at Life: The Value of Legislative Action and Institutional Leadership for DACA Students

Science.gov (United States)

Patel, Pooja

2017-01-01

Signed under the Obama administration, Deferred Action for Childhood Arrivals (DACA) grants a working permit to those who entered the U.S. before age 16, allowing students to enroll at institutions of higher education and join the military. In June 2017, the head of the Department of Homeland Security, John Kelly said that the DACA program would…

A School Shooting Plot Foiled

Science.gov (United States)

Swezey, James A.; Thorp, Kimberly A.

2010-01-01

Dinkes, Cataldi, and Lin-Kelly (2007) claims that 78% of public schools reported one or more violent incidents during the 2005/2006 school year. School shootings are a rare but real threat on school campuses. Shootings at private schools are even less frequent with only a few recorded examples in the United States. This case study examines how a…

Effect of a Metal Deactivator Fuel Additive on Fuel Deposition in Fuel Atomizers at High Temperature

Science.gov (United States)

1992-08-01

ARMY NATICK RD&E CENTER DEVELOPMENT AND ENGINEERING CTR ATTN: SATNC-U ATUN : SATBE-F I NATICK MA 01760-5020 SATBE-FL 10 SATBE-BT 2 DIRECTOR SATBE-TQ 1...SFT (MR MAKRIS) I WASHINGTON DC 20330 SAALC/LDPE (MR ELLIOT) 1 KELLY AIR FORCE BASE TX 78241 CDR US AIR FORCE WRIGHT AERO LAB CDR ATUN : POSF (MR

Thoughts on Improvable Objects, Contradiction and Object/Tool Reciprocity in a Study of Zoo Educator Professional Development

Science.gov (United States)

Ash, Doris B.; Kelly, Lisa-Anne DeGregoria

2013-01-01

In this forum we discuss three aspects designed to clarify and extend Kelly and Kassing's paper. These are the roles of improvable objects, contradiction and object/tool reciprocity. In each case we cite relevant literature and pose questions to the field. Our goal is to seed ideas for future discussions concerning the role of activity theory…

A Response to Reviewer Comments Regarding the Manuscript, "Rule-Governed Behavior and Self-Control in Children with ADHD: A Theoretical Interpretation"

Science.gov (United States)

Barry, Leasha M.; Kelly, Melissa A.

2006-01-01

The authors appreciate the opportunity to respond to the issues raised in a review of the manuscript, "Rule-Governed Behavior and Self-Control in Children with ADHD: A Theoretical Interpretation" submitted by Leasha M. Barry and Melissa A. Kelly. Many of the points brought to light in the review are indeed useful for discussion and provide…

Feasibility of progressive strength training shortly after hip fracture surgery

DEFF Research Database (Denmark)

Overgaard, Jan; Kristensen, Morten T

2013-01-01

To investigate the feasibility of a 6-wk progressive strength-training programme commenced shortly after hip fracture surgery in community-dwelling patients.......To investigate the feasibility of a 6-wk progressive strength-training programme commenced shortly after hip fracture surgery in community-dwelling patients....

Brain connectivity during verbal working memory in children and adolescents

NARCIS (Netherlands)

G.E. van den Bosch (Gerbrich); H.E. Marroun (Hanan); M. Schmidt (Marcus); D. Tibboel (Dick); D.S. Manoach (Dara); V.D. Calhoun (Vince); T.J.H. White (Tonya)

2014-01-01

textabstractWorking memory (WkM) is a fundamental cognitive process that serves as a building block for higher order cognitive functions. While studies have shown that children and adolescents utilize similar brain regions during verbal WkM, there have been few studies that evaluate the

Response of male turkeys hatched from first-cycle and force-molted breeder hens to a regimen providing progressive feeds by weight and the value of increased lysine prior to marketing.

Science.gov (United States)

Moran, E T; Krueger, K K; Acar, N

1992-11-01

Male poults originating from 41- and 85-wk-old Nicholas Large White breeder turkey hens were compared using a six-feed system provided on the basis of weight. Each source of poult was compared further in its response to lysine at .65 and .80% in the final feed (14.5% CP and 3.40 kcal AMEn/g) before marketing at 18 wk of age. Poults from 85-wk-old hens were heavier at placement than those from 41-wk-old hens. Equalization of body weights occurred once the allotment of starting feed had been consumed and for the most part remained similar thereafter. Increasing lysine content of the final feed did not improve body weight of both sources of birds at marketing (P < .13). Feed conversions included accrued mortality, and treatment differences were not apparent. Commercial processing of the flock and measurements on sample birds indicated no ready differences in chilled carcass yield nor proportions of parts occurred among treatments. The overall effects of breeder age with the progeny were negligible, and the .65% level of lysine that presently serves as the 1984 National Research Council minimum requirement when associated with 14% CP and 3.30 kcal/g appears to be adequate for the Nicholas strain of turkey from 16 to 18 wk of age.

Restoration of strength despite low stress and abnormal imaging after Achilles injury.

Science.gov (United States)

Trudel, Guy; Doherty, Geoffrey P; Koike, Yoichi; Ramachandran, Nanthan; Lecompte, Martin; Dinh, Laurent; Uhthoff, Hans K

2009-11-01

To determine the usefulness of clinical imaging in predicting the mechanical properties of rabbit Achilles tendons after acute injury. We created a 2 x 7-mm full-thickness central tendon defect in one Achilles tendon of healthy rabbits. Rabbits in groups of 10 were killed immediately and 4 and 8 wk after surgery (n = 30). We then performed magnetic resonance (MR) imaging, ultrasonography (US), bone mineral densitometry (BMD), and mechanical testing to failure using a dual-cryofixation assembly on experimental and contralateral tendons. The main outcome measures included tendon dimensions, optical density (OD) of T1-weighted, proton density (PD), and T2-weighted MR sequences, US focal abnormalities, BMD of the calcaneus, and stress and peak load to failure. On MR imaging and US, all dimensions of the injured tendons after 2 wk and more were greater than those of the contralateral tendons (P tendons at both 4 wk (39 +/- 9 vs 77 +/- 16 N x mm(-2)) and 8 wk (58 +/- 6 vs 94 +/- 26 N x mm(-2); P tendons, higher T1-weighted OD correlated with lower peak load (r = -0.46; P tendon of lower stress. These findings support progressive physical loading 4 wk after an Achilles tendon injury. T1-weighted OD constituted a marker of tendon mechanical recovery.

Expression Profiles of Cellular Retinol-binding Protein, Type II (CRBP II in Erlang Mountainous Chickens

Directory of Open Access Journals (Sweden)

H. D. Yin

2014-03-01

Full Text Available Cellular retinol-binding protein II (CRBP II belongs to the family of cellular retinol-binding proteins and plays a major role in absorption, transport, and metabolism of vitamin A. In addition, because vitamin A is correlated with reproductive performance, we measured CRBP II mRNA abundance in erlang mountainous chickens by real-time PCR using the relative quantification method. The expression of CRBP II showed a tissue-specific pattern and egg production rate-dependent changes. The expression was very high (p<0.05 in jejunum and liver, intermediate in kidney, ovary, and oviduct, and lowest (p<0.05 in heart, hypothalamus, and pituitary. In the hypothalamus, oviduct, ovary, and pituitary, CRBP II mRNA abundance were correlated to egg production rate, which increased from 12 wk to 32 wk, peaked at 32 wk relative to the other time points, and then decreased from 32 wk to 45 wk. In contrast, the expression of CRBP II mRNA in heart, jejunum, kidney, and liver was not different at any of the ages evaluated in this study. These data may help to understand the genetic basis of vitamin A metabolism, and suggest that CRBP II may be a candidate gene to affect egg production traits in chickens.

Outrunning major weight gain: a prospective study of 8,340consistent runners during 7 years of follow-up

Energy Technology Data Exchange (ETDEWEB)

Williams, Paul T.

2006-01-06

Background: Body weight increases with aging. Short-term,longitudinal exercise training studies suggest that increasing exerciseproduces acute weight loss, but it is not clear if the maintenance oflong-term, vigorous exercise attenuates age-related weight gain inproportion to the exercise dose. Methods: Prospective study of 6,119 maleand 2,221 female runners whose running distance changed less than 5 km/wkbetween their baseline and follow-up survey 7 years later. Results: Onaverage, men who ran modest (0-24 km/wk), intermediate (24-48 km/wk) orprolonged distances (>_48 km/wk) all gained weight throughage 64,however, those who ran ?48 km/wk had one-half the average annual weightgain of those who ran<24 km/wk. Age-related weight gain, and itsreduction by running, were both greater in younger than older men. Incontrast, men s gain in waist circumference with age, and its reductionby running, were the same in older and younger men. Women increased theirbody weight and waist and hip circumferences over time, regardless ofage, which was also reduced in proportion to running distance. In bothsexes, running did not attenuate weight gain uniformly, but ratherdisproportionately prevented more extreme increases. Conclusion: Men andwomen who remain vigorously active gain less weight as they age and thereduction is in proportion to the exercise dose.

Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans

Directory of Open Access Journals (Sweden)

Line Larry L

2010-03-01

Full Text Available Abstract Background Astaxanthin modulates immune response, inhibits cancer cell growth, reduces bacterial load and gastric inflammation, and protects against UVA-induced oxidative stress in in vitro and rodent models. Similar clinical studies in humans are unavailable. Our objective is to study the action of dietary astaxanthin in modulating immune response, oxidative status and inflammation in young healthy adult female human subjects. Methods Participants (averaged 21.5 yr received 0, 2, or 8 mg astaxanthin (n = 14/diet daily for 8 wk in a randomized double-blind, placebo-controlled study. Immune response was assessed on wk 0, 4 and 8, and tuberculin test performed on wk 8. Results Plasma astaxanthin increased (P helper, Tcytotoxic or natural killer cells. A higher percentage of leukocytes expressed the LFA-1 marker in subjects given 2 mg astaxanthin on wk 8. Subjects fed 2 mg astaxanthin had a higher tuberculin response than unsupplemented subjects. There was no difference in TNF and IL-2 concentrations, but plasma IFN-γ and IL-6 increased on wk 8 in subjects given 8 mg astaxanthin. Conclusion Therefore, dietary astaxanthin decreases a DNA damage biomarker and acute phase protein, and enhances immune response in young healthy females.

Effects of feeding unlimited amounts of milk replacer for the first 5 weeks of age on rumen and small intestinal growth and development in dairy calves.

Science.gov (United States)

Schäff, C T; Gruse, J; Maciej, J; Pfuhl, R; Zitnan, R; Rajsky, M; Hammon, H M

2018-01-01

The development of the gastrointestinal tract in newborn calves is essential for sufficient nutrient uptake. An intensive milk feeding during the neonatal period may impair the rumen development in calves. The aim of this study was to investigate effects of milk replacer (MR) feeding in unlimited amounts for the first 5 wk of age on the gastrointestinal growth and development in preruminant calves at wk 9 of age. Twenty-eight newborn Holstein and Holstein × Charolais crossbred calves (19 male and 9 female) were fed MR ad libitum (ADLIB) or in restricted amounts (6 L per day; RES) until wk 5 of age. Thereafter, the MR intake of ADLIB was gradually reduced at wk 6 and 7, and all calves received 6 L of MR per day until wk 9 of age. In wk 9, calves were slaughtered and carcass and organ weight as well as rumen papilla size in the atrium, ventral sac, and ventral blind sac, and villus size of the mucosa in the small intestine (duodenum; proximal, mid, and distal jejunum; and ileum) were determined. The expression of mRNA associated with the local insulin-like growth factor (IGF) system was measured in the rumen epithelium. Ad libitum MR feeding increased MR intake and growth in ADLIB without influencing concentrate intake compared with RES. Carcass weight in wk 9 was greater in ADLIB than in RES. The density of the rumen papillae in the atrium and ventral blind sac was greater in RES than in ADLIB calves, but surface area of the epithelium was not different between groups in the investigated regions of the rumen. The mRNA abundance of IGF1 in the atrium tended to be greater and the IGFR1 mRNA abundance in the ventral sac tended to be lower in the ADLIB than in the RES feeding group. The rumen pH and volatile fatty acid concentrations were not affected by MR feeding intensity. In mid-jejunum, villus circumference was greater in ADLIB than in RES calves. In the distal jejunum, villus surface area and the villus height/crypt depth ratio were greater and the villus

Multi-proxy monitoring approaches at Kangaroo Island, South Australia

Science.gov (United States)

Dixon, Bronwyn; Drysdale, Russell; Tyler, Jonathan; Goodwin, Ian

2017-04-01

Interpretations of geochemical signals preserved in young speleothems are greatly enhanced by comprehensive cave-site monitoring. In the light of this, a cave monitoring project is being conducted concurrently with the development of a new palaeoclimate record from Kelly Hill Cave (Kangaroo Island, South Australia). The site is strategically located because it is situated between longer-lived monitoring sites in southeastern and southwestern Australia, as well as being climatically 'upstream' from major population and agricultural centres. This study aims to understand possible controls on speleothem δ18O in Kelly Hill Cave through i. identification of local and regional δ18O drivers in precipitation; and ii. preservation and modification of climatic signals within the epikarst as indicated by dripwater δ18O. These aims are achieved through analysis of a five-year daily rainfall (amount and δ18O) dataset in conjunction with in-cave drip monitoring. Drivers of precipitation δ18O were identified through linear regression between δ18O values and local meteorological variables, air-parcel back trajectories, and synoptic-typing. Synoptically driven moisture sources were identified through the use of NCEP/NCAR climate reanalysis sea-level pressure, precipitable moisture, and outgoing longwave radiation data in order to trace moisture sources and travel mechanisms from surrounding ocean basins. Local controls on δ18O at Kelly Hill Cave are consistent with published interpretations of southern Australia sites, with oxygen isotopes primarily controlled by rainfall amount on both daily and monthly time scales. Back-trajectory analysis also supports previous observations that the Southern Ocean is the major source for moisture-bearing cold-front systems. However, synoptic typing of daily rainfall δ18O and amount extremes reveals a previously unreported tropical connection and moisture source. This tropical connection appears to be strongest in summer and autumn, but

Locomotor activity and catecholamine receptor binding in adult normotensive and spontaneously hypertensive rats

International Nuclear Information System (INIS)

Hellstrand, K.; Engel, J.

1980-01-01

The binding of 3 H-WB 4101, an α 1 -adrenoceptor antagonist, the membranes of the cerebral cortex, the hypothalamus, and the lower brainstem was examined in adult spontaneously hypertensive (SH) rats and in normotensive Wistar Kyoto (WK) controls. The specific binding of 3 H-WB 4101 (0.33 nM) was significantly higher in homogenates from the cerebral cortex of SH rats as compared to WK rats. No differences were detected between SH and WK rats in the specific binding of 3 H-spiroperidol (0.25 nM), a dopamine receptor antagonist, to membranes from the corpus striatum and the limbic forebrain. The locomotor activity was significantly higher in SH rats as compared to WK controls, in all probability due to a lack of habituation to environmental change. It is suggested that the high reactivity of SH rats is related to a disfunction in the noradrenergic neurons in the central nervous system. (author)

Early release of neonatal ureteral obstruction preserves renal function

DEFF Research Database (Denmark)

Shi, Yimin; Pedersen, Michael; Li, Chunling

2004-01-01

was left in place or released after 1 or 4 wk. Renal blood flow (RBF) and kidney size were measured sequentially over 24 wk using MRI. In rats in which the obstruction was left in place, RBF of the obstructed kidney was progressively reduced to 0.92 ± 0.17 vs. 1.79 ± 0.12 ml·min−1·100 g body wt−1 (P ...The incidence of congenital hydronephrosis is ∼1% and is often associated with renal insufficiency. It is unknown whether early release is essential to prevent deterioration of renal function. Rats were subjected to partial unilateral ureteral obstruction (PUUO) on postnatal day 2. The obstruction...... downregulation of Na-K-ATPase to 62 ± 7%, aquaporin-1 to 53 ± 3%, and aquaporin-3 to 53 ± 7% of sham levels. Release after 1 wk completely prevented development of hydronephrosis, reduction in RBF and glomerular filtration rate, and downregulation of renal transport proteins, whereas release after 4 wk had...

Programming of intermediate metabolism in young lambs affected by late gestational maternal undernourishment

DEFF Research Database (Denmark)

Husted, Sanne; Nielsen, Mette Olaf; Tygesen, Malin Plumhoff

2007-01-01

Effects of moderate maternal undernourishment during late gestation on the intermediary metabolism and maturational changes in young lambs were investigated. 20 twin-bearing sheep, bred to two different rams, were randomly allocated the last 6 wk of gestation to either a NORM diet [barley, protein...... supplement, and silage ad libitum ˜ 15 MJ metabolizable energy (ME/day] or a LOW diet (50% of ME intake in NORM, offered exclusively as silage ¨7 MJ ME/day). Post partum, ewes were fed to requirement. After weaning, lambs were fed concentrate and hay ad libitum. At 10 and 19 wk of age, lambs wee subjected...... to an intravenous glucose tolerance test (IGTT) followed by 24 h of fasting. Heat energy (HE) was determined in a respiration chamber at 9 or 20 wk of age. LOW lambs had a lower birth weight and continued to be lighter throughout the experiment. Glucose tolerance did not differ between groups. However, 19-wk...

The dose-response relationship of balance training in physically active older adults.

Science.gov (United States)

Maughan, Kristen K; Lowry, Kristin A; Franke, Warren D; Smiley-Oyen, Ann L

2012-10-01

A 6-wk group balance-training program was conducted with physically active older adults (based on American College of Sports Medicine requirements) to investigate the effect of dose-related static and dynamic balance-specific training. All participants, age 60-87 yr, continued their regular exercise program while adding balance training in 1 of 3 doses: three 20-min sessions/wk (n = 20), one 20-min session/wk (n = 21), or no balance training (n = 19). Static balance (single-leg-stance, tandem), dynamic balance (alternate stepping, limits of stability), and balance confidence (ABC) were assessed pre- and posttraining. Significant interactions were observed for time in single-leg stance, excursion in limits of stability, and balance confidence, with the greatest increase observed in the group that completed 3 training sessions/wk. The results demonstrate a dose-response relationship indicating that those who are already physically active can improve balance performance with the addition of balance-specific training.

Inverse spectral results for Schrödinger operators on the unit interval with partial information given on the potentials

Science.gov (United States)

Amour, L.; Faupin, J.; Raoux, T.

2009-03-01

We pursue the analysis of the Schrödinger operator on the unit interval in inverse spectral theory initiated in the work of Amour and Raoux ["Inverse spectral results for Schrödinger operators on the unit interval with potentials in Lp spaces," Inverse Probl. 23, 2367 (2007)]. While the potentials in the work of Amour and Raoux belong to L1 with their difference in Lp (1≤p<∞), we consider here potentials in Wk,1 spaces having their difference in Wk,p, where 1≤p≤+∞, k ɛ{0,1,2}. It is proved that two potentials in Wk,1([0,1]) being equal on [a,1] are also equal on [0,1] if their difference belongs to Wk,p([0,a]) and if the number of their common eigenvalues is sufficiently high. Naturally, this number decreases as the parameter a decreases and as the parameters k and p increase.

Effects of prenatal exposure to ionizing radiation

International Nuclear Information System (INIS)

Miller, R.W.

1990-01-01

Prenatal exposure to ionizing radiation induces some effects that are seen at birth and others that cannot be detected until later in life. Data from A-bomb survivors in Hiroshima and Nagasaki show a diminished number of births after exposure under 4 wk of gestational age. Although a wide array of congenital malformations has been found in animal experimentation after such exposure to x rays, in humans only small head size (exposure at 4-17 wk) and mental retardation (exposure primarily at 8-15 wk) have been observed. In Hiroshima, small head size occurred after doses of 0.10-0.19 Gy or more, and an excess of mental retardation at 0.2-0.4 Gy or more. Intelligence test scores were reduced among A-bomb survivors exposed at 8-15 wk of gestational age by 21-29 IQ points per Gy. Other effects of in-utero exposure to atomic radiation include long-lasting complex chromosome abnormalities

Effects of prenatal exposure to ionizing radiation

Energy Technology Data Exchange (ETDEWEB)

Miller, R.W. (National Cancer Institute, Bethesda, MD (USA))

1990-07-01

Prenatal exposure to ionizing radiation induces some effects that are seen at birth and others that cannot be detected until later in life. Data from A-bomb survivors in Hiroshima and Nagasaki show a diminished number of births after exposure under 4 wk of gestational age. Although a wide array of congenital malformations has been found in animal experimentation after such exposure to x rays, in humans only small head size (exposure at 4-17 wk) and mental retardation (exposure primarily at 8-15 wk) have been observed. In Hiroshima, small head size occurred after doses of 0.10-0.19 Gy or more, and an excess of mental retardation at 0.2-0.4 Gy or more. Intelligence test scores were reduced among A-bomb survivors exposed at 8-15 wk of gestational age by 21-29 IQ points per Gy. Other effects of in-utero exposure to atomic radiation include long-lasting complex chromosome abnormalities.

Different kinetic in incorporation and depletion of n-3 fatty acids in erythrocytes and leukocytes of mice

DEFF Research Database (Denmark)

Mu, Huiling; Thogersen, Regitze Louise; Maaetoft-Udsen, Kristina

2006-01-01

during a 6-wk feeding period. Over the first 3-wk period (the incorporation period) the mice were fed a special diet with a high n-3/n-6 PUFA ratio. In the following 3-wk period (the depletion period) the mice were fed a standard chow diet. A linear increase of the concentration of EPA and DHA...... in erythrocyte membranes was observed during the incorporation period, whereas a stagnation was observed after the second week for leukocytes. The level of EPA did not fall to the background level after the depletion period, and the level of DHA was kept almost constant during the depletion period...... in the erythrocyte membranes. In leukocytes the concentration of both EPA and DHA decreased during the depletion period, but did not reach the background level after the 3-wk depletion. In conclusion, the kinetics of EPA and DHA in the different cells are different. The rate of incorporation is faster than...

Micronutrient quality of weight-loss diets that focus on macronutrients: results from the A TO Z study123

Science.gov (United States)

Gardner, Christopher D; Kim, Soowon; Bersamin, Andrea; Dopler-Nelson, Mindy; Otten, Jennifer; Oelrich, Beibei; Cherin, Rise

2010-01-01

Background: Information on the micronutrient quality of alternative weight-loss diets is limited, despite the significant public health relevance. Objective: Micronutrient intake was compared between overweight or obese women randomly assigned to 4 popular diets that varied primarily in macronutrient distribution. Design: Dietary data were collected from women in the Atkins (n = 73), Zone (n = 73), LEARN (Lifestyle, Exercise, Attitudes, Relationships, Nutrition) (n = 73), and Ornish (n = 72) diet groups by using 3-d, unannounced 24-h recalls at baseline and after 8 wk of instruction. Nutrient intakes were compared between groups at 8 wk and within groups for 8-wk changes in risk of micronutrient inadequacy. Results: At 8 wk, significant differences were observed between groups for all macronutrients and for many micronutrients (P macronutrient composition should attend to the overall quality of the diet, including the adequacy of micronutrient intakes. Concerning calorie-restricted diets, there may be a micronutrient advantage to diets providing moderately low carbohydrate amounts and that contain nutrient-dense foods. PMID:20573800

Systemic metabolic derangement, pulmonary effects, and insulin insufficiency following subchronic ozone exposure in rats

International Nuclear Information System (INIS)

Miller, Desinia B.; Snow, Samantha J.; Henriquez, Andres; Schladweiler, Mette C.; Ledbetter, Allen D.; Richards, Judy E.; Andrews, Debora L.; Kodavanti, Urmila P.

2016-01-01

Acute ozone exposure induces a classical stress response with elevated circulating stress hormones along with changes in glucose, protein and lipid metabolism in rats, with similar alterations in ozone-exposed humans. These stress-mediated changes over time have been linked to insulin resistance. We hypothesized that acute ozone-induced stress response and metabolic impairment would persist during subchronic episodic exposure and induce peripheral insulin resistance. Male Wistar Kyoto rats were exposed to air or 0.25 ppm or 1.00 ppm ozone, 5 h/day, 3 consecutive days/week (wk) for 13 wks. Pulmonary, metabolic, insulin signaling and stress endpoints were determined immediately after 13 wk or following a 1 wk recovery period (13 wk + 1 wk recovery). We show that episodic ozone exposure is associated with persistent pulmonary injury and inflammation, fasting hyperglycemia, glucose intolerance, as well as, elevated circulating adrenaline and cholesterol when measured at 13 wk, however, these responses were largely reversible following a 1 wk recovery. Moreover, the increases noted acutely after ozone exposure in non-esterified fatty acids and branched chain amino acid levels were not apparent following a subchronic exposure. Neither peripheral or tissue specific insulin resistance nor increased hepatic gluconeogenesis were present after subchronic ozone exposure. Instead, long-term ozone exposure lowered circulating insulin and severely impaired glucose-stimulated beta-cell insulin secretion. Thus, our findings in young-adult rats provide potential insights into epidemiological studies that show a positive association between ozone exposures and type 1 diabetes. Ozone-induced beta-cell dysfunction may secondarily contribute to other tissue-specific metabolic alterations following chronic exposure due to impaired regulation of glucose, lipid, and protein metabolism. - Highlights: • Subchronic episodic ozone exposure caused pulmonary and metabolic effects. • These

Constant and changing photoperiods in the laying period for broiler breeders allowed [corrected] normal or accelerated growth during the rearing period.

Science.gov (United States)

Lewis, P D; Gous, R M

2006-02-01

Broiler breeder pullets were grown on 8-h photoperiods to 2.23 or 2.42 kg of BW at 20 wk, and then transferred abruptly to 11- or 16-h photoperiods. Subsequently, some of the 11-h photoperiod birds were given 15-min increases in day length weekly or a 1-h increase every 4 wk to reach 16 h of light at 54 wk. The birds transferred abruptly to a 16-h photoperiod at 20 wk matured 4 d earlier than 11-h photoperiod birds, required 500 g less feed to reach 50% lay, but, because of a 3% lower rate of lay after peak, produced 5 fewer eggs to 60 wk. However, the number of settable eggs was similar for the 2 groups because the 11-h photoperiod birds laid more eggs on the floor, resulting in more cracked and dirty eggs. The 11-h photoperiod birds converted feed into egg more efficiently, and were 100 g heavier at end of lay. Increasing the photoperiod in 15-min or 1-h increments from 11 to 16 h during the laying cycle depressed egg production. Mean egg weight and mortality were similar for all lighting groups. The heavier BW birds at 20 wk reached maturity 1 d earlier, but used 1 kg more feed to reach maturity, laid 5 fewer total eggs (because of a 3% lower rate of lay after peak), produced 7 more unsettable eggs (because more eggs were laid on the floor), and converted feed into egg less efficiently than did the lighter BW birds. Mean egg weight, BW at 57 wk, and mortality were similar for both groups. There was no significant light x growth interaction for any performance parameter. It is concluded that there is no benefit to egg production from extending the photoperiod to 16 h when broiler breeders are kept in light-proofed housing, especially if they have access to illuminated nest boxes.

Chicks change their pecking behaviour towards stationary and mobile food sources over the first 12 weeks of life: improvement and discontinuities

Directory of Open Access Journals (Sweden)

Kenneth J. Murphy

2014-10-01

Full Text Available Chicks (Gallus gallus domesticus learn to peck soon after hatching and then peck in rapid bursts or bouts with intervals of non-pecking activity. The food sources may be static such as seeds and chick crumb, or mobile such as a mealworm. Here, changes with age in pecking toward chick crumb and a mealworm were measured.Chicks were reared in pairs and their pecking of crumb food was video recorded in their pair housed environment, from food presentation, every third day from day 8 (wk 2 to day 65 (wk 10. Peck rate at crumb food reached maximum levels at day 32 (wk 5, and then declined, fitting a quadratic model, with no sex, sex of cagemate, or box order effects. Within bouts the peck rate was higher and it increased to day 41 (wk 6 and then declined, and here males pecked faster than females. A change in dietary protein concentration from 22% to 18% at day 28 (wk 4 had no effect on subsequent peck rate.Pecking at and consumption of a mealworm in pair housed chicks were measured weekly from wks [5 to 12]. The latency to first worm peck and latency to swallow decreased to wk 8 and increased thereafter. The peck rate to first wormpeck and number of pecks to swallow increased to wk 8 and then declined paralleling the changes with crumb food. The increase in peck rate is coupled with an increase in efficiency in worm catching.The results are consistent with the view that the improvement in pecking ability and accuracy compliments change in nutritional requirement best served by an invertebrate food (IF source requiring speed to achieve feeding success, especially with live prey. When this food source is no longer crucial these associated skill levels decline. An appreciation of the role of domestic fowl in controlling insect populations, at farm level, that are often vectors in disease spread is lacking.

Chicks change their pecking behaviour towards stationary and mobile food sources over the first 12 weeks of life: improvement and discontinuities.

Science.gov (United States)

Murphy, Kenneth J; Hayden, Thomas J; Kent, John P

2014-01-01

Chicks (Gallus gallus domesticus) learn to peck soon after hatching and then peck in rapid bursts or bouts with intervals of non-pecking activity. The food sources may be static such as seeds and chick crumb, or mobile such as a mealworm. Here, changes with age in pecking toward chick crumb and a mealworm were measured. Chicks were reared in pairs and their pecking of crumb food was video recorded in their pair housed environment, from food presentation, every third day from day 8 (wk 2) to day 65 (wk 10). Peck rate at crumb food reached maximum levels at day 32 (wk 5), and then declined, fitting a quadratic model, with no sex, sex of cagemate, or box order effects. Within bouts the peck rate was higher and it increased to day 41 (wk 6) and then declined, and here males pecked faster than females. A change in dietary protein concentration from 22% to 18% at day 28 (wk 4) had no effect on subsequent peck rate. Pecking at and consumption of a mealworm in pair housed chicks were measured weekly from wks [5 to 12]. The latency to first worm peck and latency to swallow decreased to wk 8 and increased thereafter. The peck rate to first wormpeck and number of pecks to swallow increased to wk 8 and then declined paralleling the changes with crumb food. The increase in peck rate is coupled with an increase in efficiency in worm catching. The results are consistent with the view that the improvement in pecking ability and accuracy compliments change in nutritional requirement best served by an invertebrate food (IF) source requiring speed to achieve feeding success, especially with live prey. When this food source is no longer crucial these associated skill levels decline. An appreciation of the role of domestic fowl in controlling insect populations, at farm level, that are often vectors in disease spread is lacking.

Evidence of In Vivo Absorption of Lactate and Modulation of Short Chain Fatty Acid Absorption from the Reticulorumen of Non-Lactating Cattle Fed High Concentrate Diets.

Directory of Open Access Journals (Sweden)

Muhammad Qumar

Full Text Available Short-chain fatty acids (SCFAs and lactate are endproducts of rumen fermentation and important energy sources for the host ruminant. Because their rapid accumulation results in ruminal acidosis, enhancement of the absorption of SCFA and lactate across reticuloruminal wall is instrumental in increasing energy supply and preventing ruminal acidosis in cattle. This study investigated whether the reticuloruminal absorption of SCFAs and lactate was altered by different strategies of high concentrate feeding. Eight rumen-cannulated, non-lactating Holstein cows were fed a forage-only diet (baseline and then gradually adapted over 6 d to a 60% concentrate level. Thereafter, this concentrate-rich diet was fed for 4 wk either continuously (Con; n = 8 or interruptedly (Int; n = 8. Absorption of SCFAs and lactate was determined in vivo from the experimental buffer introduced into the washed reticulorumen. The buffer contained acetate, propionate, butyrate and lactate at a concentration of 60, 30, 10 and 5 mmol/L, respectively and Cr-EDTA as a marker for correcting ruminal water fluxes. The reticuloruminal absorption after 35 and 65 min of buffer incubation was measured at the baseline, after 1 wk of 60% concentrate feeding in the interrupted model (Int-1 and after 4 wk of concentrate feeding in both feeding models (Int-4 and Con-4. Data showed that the absorption rates of individual and total SCFAs during the first 35 min of incubation of Con-4 were highest (~1.7 times compared to baseline, while Int-1 and Int-4 were similar to respective baseline. Lactate was not absorbed during forage-only baseline and 1-wk concentrate feeding, but after 4-wk feeding of concentrates in both models. In conclusion, SCFAs absorption across the reticulorumen of non-lactating cattle was enhanced by the 4-wk continuous concentrate feeding, which seems to be more advantageous in terms of rumen acidosis prevention compared to the interrupted feeding model. The study provides

Fibrolytic enzyme and ammonia application effects on the nutritive value, intake, and digestion kinetics of bermudagrass hay in beef cattle.

Science.gov (United States)

Romero, J J; Zarate, M A; Queiroz, O C M; Han, J H; Shin, J H; Staples, C R; Brown, W F; Adesogan, A T

2013-09-01

The objectives were to compare the effect of exogenous fibrolytic enzyme (Biocellulase A20) or anhydrous ammonia (4% DM) treatment on the nutritive value, voluntary intake, and digestion kinetics of bermudagrass (Cynodon dactylon cultivar Coastal) hay harvested after 2 maturities (5- and 13-wk regrowths). Six individually housed, ruminally cannulated Brangus steers (BW 325 ± 10 kg) were used in an experiment with a 6 × 6 Latin square design with a 3 (additives) × 2 (maturities) factorial arrangement of treatments. Each period consisted of 14 d of adaptation and 7, 4, 1, 1, and 4 d for measuring in vivo digestibility, in situ degradability, no measurements, rumen liquid fermentation and passage indices, and rate of solid passage, respectively. Steers were fed hay for ad libitum intake and supplemented with sugarcane molasses and distillers grain (supplement total of 2.88 kg DM/d). Enzyme did not affect the nutritional composition of hay but ammonia treatment decreased hay NDF, hemicellulose, and ADL concentrations and increased the CP concentration particularly for the mature lignified 13-wk hay. The enzyme increased NDF and hemicellulose digestibility of the 5-wk hay but decreased those of the 13-wk hay. Ammoniation decreased intake of hay but increased digestibility of DM, OM, NDF, hemicellulose, ADF, and cellulose and increased the ruminal in situ soluble and potentially digestible fractions and the rate of DM degradation of the 13-wk hay. Also, ammoniation increased the concentrations of ruminal NH3, total VFA, acetate, and butyrate but enzyme treatment did not. Neither enzyme addition nor ammoniation affected rate of liquid and solid passage. In conclusion, ammoniation decreased the concentration of most fiber fractions, decreased the intake of hays, and increased their CP concentration, in vivo digestibility, and in situ degradability at both maturities whereas enzyme application increased fiber digestibility of the 5-wk hay but decreased it in the case of

Systemic metabolic derangement, pulmonary effects, and insulin insufficiency following subchronic ozone exposure in rats

Energy Technology Data Exchange (ETDEWEB)

Miller, Desinia B. [Curriculum in Toxicology, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina (United States); Snow, Samantha J. [Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC (United States); Henriquez, Andres [Curriculum in Toxicology, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina (United States); Schladweiler, Mette C.; Ledbetter, Allen D.; Richards, Judy E.; Andrews, Debora L. [Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC (United States); Kodavanti, Urmila P., E-mail: kodavanti.urmila@epa.gov [Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC (United States)

2016-09-01

Acute ozone exposure induces a classical stress response with elevated circulating stress hormones along with changes in glucose, protein and lipid metabolism in rats, with similar alterations in ozone-exposed humans. These stress-mediated changes over time have been linked to insulin resistance. We hypothesized that acute ozone-induced stress response and metabolic impairment would persist during subchronic episodic exposure and induce peripheral insulin resistance. Male Wistar Kyoto rats were exposed to air or 0.25 ppm or 1.00 ppm ozone, 5 h/day, 3 consecutive days/week (wk) for 13 wks. Pulmonary, metabolic, insulin signaling and stress endpoints were determined immediately after 13 wk or following a 1 wk recovery period (13 wk + 1 wk recovery). We show that episodic ozone exposure is associated with persistent pulmonary injury and inflammation, fasting hyperglycemia, glucose intolerance, as well as, elevated circulating adrenaline and cholesterol when measured at 13 wk, however, these responses were largely reversible following a 1 wk recovery. Moreover, the increases noted acutely after ozone exposure in non-esterified fatty acids and branched chain amino acid levels were not apparent following a subchronic exposure. Neither peripheral or tissue specific insulin resistance nor increased hepatic gluconeogenesis were present after subchronic ozone exposure. Instead, long-term ozone exposure lowered circulating insulin and severely impaired glucose-stimulated beta-cell insulin secretion. Thus, our findings in young-adult rats provide potential insights into epidemiological studies that show a positive association between ozone exposures and type 1 diabetes. Ozone-induced beta-cell dysfunction may secondarily contribute to other tissue-specific metabolic alterations following chronic exposure due to impaired regulation of glucose, lipid, and protein metabolism. - Highlights: • Subchronic episodic ozone exposure caused pulmonary and metabolic effects. • These

Desmin loss and mitochondrial damage precede left ventricular systolic failure in volume overload heart failure.

Science.gov (United States)

Guichard, Jason L; Rogowski, Michael; Agnetti, Giulio; Fu, Lianwu; Powell, Pamela; Wei, Chih-Chang; Collawn, James; Dell'Italia, Louis J

2017-07-01

Heart failure due to chronic volume overload (VO) in rats and humans is characterized by disorganization of the cardiomyocyte desmin/mitochondrial network. Here, we tested the hypothesis that desmin breakdown is an early and continuous process throughout VO. Male Sprague-Dawley rats had aortocaval fistula (ACF) or sham surgery and were examined 24 h and 4 and 12 wk later. Desmin/mitochondrial ultrastructure was examined by transmission electron microscopy (TEM) and immunohistochemistry (IHC). Protein and kinome analysis were performed in isolated cardiomyocytes, and desmin cleavage was assessed by mass spectrometry in left ventricular (LV) tissue. Echocardiography demonstrated a 40% decrease in the LV mass-to-volume ratio with spherical remodeling at 4 wk with ACF and LV systolic dysfunction at 12 wk. Starting at 24 h and continuing to 4 and 12 wk, with ACF there is TEM evidence of extensive mitochondrial clustering, IHC evidence of disorganization associated with desmin breakdown, and desmin protein cleavage verified by Western blot analysis and mass spectrometry. IHC results revealed that ACF cardiomyocytes at 4 and 12 wk had perinuclear translocation of αB-crystallin from the Z disk with increased α, β-unsaturated aldehyde 4-hydroxynonelal. Use of protein markers with verification by TUNEL staining and kinome analysis revealed an absence of cardiomyocyte apoptosis at 4 and 12 wk of ACF. Significant increases in protein indicators of mitophagy were countered by a sixfold increase in p62/sequestosome-1, which is indicative of an inability to complete autophagy. An early and continuous disruption of the desmin/mitochondrial architecture, accompanied by oxidative stress and inhibition of apoptosis and mitophagy, suggests its causal role in LV dilatation and systolic dysfunction in VO. NEW & NOTEWORTHY This study provides new evidence of early onset (24 h) and continuous (4-12 wk) desmin misarrangement and disruption of the normal sarcomeric and mitochondrial

Crystallization and demineralization phenomena in washed-rind cheese.

Science.gov (United States)

Tansman, Gil F; Kindstedt, Paul S; Hughes, John M

2017-11-01

This report documents an observational study of a high-moisture washed-rind cheese. Three batches of cheese were sampled on a weekly basis for 6 wk and again at wk 10. Center, under-rind, rind, and smear samples were tested for pH, moisture, and selected mineral elements. Powder x-ray diffractometry and petrographic microscopy were applied to identify and image the crystal phases. The pH of the rind increased by over 2 pH units by wk 10. The pH of the under-rind increased but remained below the rind pH, whereas the center pH decreased for most of aging and only began to rise after wk 5. Diffractograms of smear material revealed the presence of 4 crystal phases: brushite, calcite, ikaite, and struvite. The phases nucleated in succession over the course of aging, with calcite and ikaite appearing around the same time. A very small amount of brushite appeared sporadically in center and under-rind samples, but otherwise no other crystallization was observed beneath the rind. Micrographs revealed that crystals in the smear grew to over 250 μm in length by wk 10, and at least 2 different crystal phases, probably ikaite and struvite, could be differentiated by their different optical properties. The surface crystallization was accompanied by a mineral diffusion phenomenon that resulted, on average, in a 217, 95.7, and 149% increase in calcium, phosphorus, and magnesium, respectively, in the rind by wk 10. The diffusion phenomenon caused calcium, phosphorus, and magnesium to decrease, on average, by 55.0, 21.5, and 36.3%, respectively, in the center by wk 10. The present study represents the first observation of crystallization and demineralization phenomena in washed-rind cheese. The Authors. Published by the Federation of Animal Science Societies and Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

The effect of palatability of protein source on dietary selection in dairy calves.

Science.gov (United States)

Miller-Cushon, E K; Terré, M; DeVries, T J; Bach, A

2014-07-01

Evidence has shown that soybean meal is perceived as more palatable than canola meal by dairy calves in short-term preference tests. This study evaluated the effect of protein source on longer-term dietary selection of dairy calves. In experiment 1, 40 Holstein bull calves (11.4 ± 4.3 d of age) were randomly assigned to 1 of 2 choice diets for 6 wk: base starter pellet (S; 12% crude protein; CP) and high-protein pellet (40% CP) containing either (1) soybean meal (SB) or (2) canola meal (CM). In wk 7 to 8, all calves were offered a single pelleted diet containing the protein source to which they were previously exposed. In experiment 2, 22 Holstein bull calves (9.9 ± 4.6d of age) were offered, for 6 wk, a choice of 2 mixed pelleted diets: (1) 70% S and 30% SB (SB mix), or (2) 70% S and 30% CM (CM mix). In wk 7 to 8, calves were randomly assigned to 1 of 2 choice diets, as in experiment 1: (1) SB + S, or (2) CM + S. All feeds were provided ad libitum. Calves received 6 L/d of milk replacer [0.75 kg/d of dry matter (DM)] for the duration of both experiments. Feed intake was recorded daily and calves were weighed every 14 d. Feeds were sampled weekly to analyze DM and nutrient intake. Mixed diets in experiment 2 were analyzed for CP in wk 4 and 6 to assess feed sorting (calculated as actual CP intake as a percentage of predicted intake). In experiment 1, calves offered SB + S in wk 1 to 6 consumed more high-protein pellet than calves offered CM + S [73 vs. 42% of DM intake (DMI)] and, consequently, more CP (168 vs. 117 g/d). Solid feed DMI and average daily gain were similar between treatments. When offered a single diet in wk 7 to 8, calves offered starter containing soybean meal increased intake to a greater extent than calves offered the starter containing canola meal. In experiment 2, calves preferred the SB mix to CM mix (preference ratio: 0.7). Calves consumed more CP than predicted from SB mix in wk 4 and 6 (108 ± 2.0%), indicating that they were sorting in

76 FR 72025 - Noise Compatibility Program Notice for W.M. Kellogg Airport, Battle Creek, MI

Science.gov (United States)

2011-11-21

... for W.M. Kellogg Airport, Battle Creek, MI AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... exposure maps submitted by the City of Battle Creek, Michigan for W.K. Kellogg Airport under the provisions... noise compatibility program that was submitted for W.K. Kellogg Airport under part 150 in conjunction...

A randomized, masked study of triiodothyronine plus thyroxine administration in preterm infants less than 28 weeks of gestational age: Hormonal and clinical effects

NARCIS (Netherlands)

Valerio, Paolo G.; van Wassenaer, Aleid G.; de Vijlder, Jan J. M.; Kok, Joke H.

2004-01-01

A randomized, placebo-controlled, masked study was conducted of the responses of thyroid parameters, cortisol, and the cardiovascular system to a single dose of triiodothyronine (T-3) 24 h after birth, followed by a daily dose of thyroxine (T-4) during 6 wk to infants <28 wk gestational age.

Effectiveness of nutrition education, iron supplementation or both on iron status in children.

Science.gov (United States)

Kapur, D; Sharma, S; Agarwal, K N

2003-12-01

A community-based, randomized trial was designed to compare the effect of nutrition education and/or iron supplementation (weekly) on iron status of children in an urban slum in Delhi. Four hundred and fifty one children, 9-36 months of age and their caretakers (mothers), assigned to one of the following groups were included in the cohort. Group 1, nutrition education. Group 2, supplementation (with 20 mg elemental iron). Group 3, nutrition education with supplementation (with 20 mg elemental iron) and Group 4, control given placebo. The intervention program was of four months duration, with a treatment phase of 8 wk followed by 8 wk of no treatment. Post intervention, at 8 wk and at 16 wk, the hemoglobin change in the nutrition education, supplementation, nutrition education with supplementation and control groups was 2.9, 1.9, 3.8 and -5.9%, respectively and 2.1, -1.9, 0 and -9.3%, respectively (as compared to initial values). There was no significant effect of any of the intervention at 8 weeks. At 16 wk, there was significant positive effect of nutrition education group (p less than 0.05). The percent change in serum ferritin value at 16 wk in the nutrition education, supplementation, nutrition education with supplementation and control groups was 5.7, -2.3, -3.4 and -40%, respectively. Serum ferritin values were significantly higher for the nutrition education group (p nutrition education group mothers showed significantly higher nutrition knowledge and the dietary iron intake of children was significantly higher than their control group counterparts (p nutrition education did have a positive effect on the iron status possibly by improving the dietary iron intake.

Rapid suppression of growth hormone concentration by overeating: potential mediation by hyperinsulinemia.

Science.gov (United States)

Cornford, Andrea S; Barkan, Ariel L; Horowitz, Jeffrey F

2011-03-01

The very low GH concentration in obesity is commonly attributed to high body fat mass; however, the influence of overeating on GH secretion is not clear. The aim of the study was to examine the effects of 2 wk of overeating on changes in GH secretion. Subjects were admitted to the hospital and stayed within the Michigan Clinical Research Unit throughout the entire 2-wk overeating period. We studied seven healthy, nonobese men (body mass index, 24 ± 1 kg/m(2); age, 25 ± 1 yr). Subjects ate standardized meals containing 70 kcal/kg fat free mass/d (∼4000 kcal/d) for 2 wk. Twenty-four-hour plasma concentrations of GH (every 20 min) and insulin (every 2 h) were measured before overeating (baseline), on d 3, and after 2 wk of overeating. Compared with baseline, average 24-h plasma GH concentration declined nearly 80% by d 3 of overeating (1.30 ± 0.18 vs. 0.36 ± 0.09 ng/ml; P = 0.01). This marked suppression of GH secretion occurred in the absence of an increase in body weight (77.0 ± 2.2 vs. 76.4 ± 2.4 kg). At the same time, average 24-h insulin concentration doubled (16.6 ± 2.1 vs. 31.7 ± 5.8 μU/ml; P = 0.009). After 2 wk, body weight significantly increased (79.0 ± 2.1 kg; P overeating markedly suppressed GH secretion before any measurable weight gain and was accompanied by chronic hyperinsulinemia. Increased body weight and body fat by 2 wk of overeating did not further suppress GH secretion.

Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus.

Science.gov (United States)

Norris, Leigh E; Collene, Angela L; Asp, Michelle L; Hsu, Jason C; Liu, Li-Fen; Richardson, Julia R; Li, Dongmei; Bell, Doris; Osei, Kwame; Jackson, Rebecca D; Belury, Martha A

2009-09-01

Weight loss may improve glucose control in persons with type 2 diabetes. The effects of fat quality, as opposed to quantity, on weight loss are not well understood. We compared the effects of 2 dietary oils, conjugated linoleic acid (CLA) and safflower oil (SAF), on body weight and composition in obese postmenopausal women with type 2 diabetes. This was a 36-wk randomized, double-masked, crossover study. Fifty-five obese postmenopausal women with type 2 diabetes received SAF or CLA (8 g oil/d) during two 16-wk diet periods separated by a 4-wk washout period. Subjects met monthly with the study coordinator to receive new supplements and for assessment of energy balance, biochemical endpoints, or anthropometric variables. Thirty-five women completed the 36-wk intervention. Supplementation with CLA reduced body mass index (BMI) (P = 0.0022) and total adipose mass (P = 0.0187) without altering lean mass. The effect of CLA in lowering BMI was detected during the last 8 wk of each 16-wk diet period. In contrast, SAF had no effect on BMI or total adipose mass but reduced trunk adipose mass (P = 0.0422) and increased lean mass (P = 0.0432). SAF also significantly lowered fasting glucose (P = 0.0343) and increased adiponectin (P = 0.0051). No differences were observed in dietary energy intake, total fat intake, and fat quality in either diet period for either intervention. Supplementation with CLA and SAF exerted different effects on BMI, total and trunk adipose mass, and lean tissue mass in obese postmenopausal women with type 2 diabetes. Supplementation with these dietary oils may be beneficial for weight loss, glycemic control, or both.

Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on performance, hematology, metabolism, and immunocompetence of turkeys.

Science.gov (United States)

Girish, C K; Smith, T K; Boermans, H J; Karrow, N A

2008-03-01

An experiment was conducted to investigate the effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on performance, hematology, metabolism, and immunological parameters of turkeys. The efficacy of polymeric glucomannan mycotoxin adsorbent (GMA) in preventing these adverse effects was also evaluated. Three hundred 1-d-old male turkey poults were fed wheat-, corn-, and soybean meal-based starter (0 to 3 wk), grower (4 to 6 wk), developer (7 to 9 wk), and finisher (10 to 12 wk) diets formulated with uncontaminated grains, contaminated grains, and contaminated grains + 0.2% GMA. Feeding contaminated grains significantly decreased BW gains during the grower and developer phases, and GMA supplementation prevented these effects. There was no effect of diet, however, on feed intake or feed efficiency. The feeding of contaminated grains reduced total lymphocyte counts at wk 3 (P effect. Feeding contaminated grains significantly increased the percentage of CD4(+) lymphocyte populations during wk 6; however, there was no change in the percentage of CD8(+) and B-lymphocyte populations. Contact hypersensitivity to dinitrochlorobenzene, which is a CD8(+) T cell-mediated delayed-type hypersensitivity response, was significantly decreased after 24 and 72 h by feedborne mycotoxins compared with controls. Supplementation of the contaminated diet with GMA prevented the decrease in response after 24 h. Secondary antibody (IgG titer) response against SRBC antigens (CD4(+) T cell-dependent) was significantly decreased after feeding contaminated grains compared with controls. It was concluded that turkey performance and some blood and immunological parameters were adversely affected by feedborne Fusarium mycotoxins, and GMA prevented many of these effects.

Dietary Mung Bean Protein Reduces Hepatic Steatosis, Fibrosis, and Inflammation in Male Mice with Diet-Induced, Nonalcoholic Fatty Liver Disease.

Science.gov (United States)

Watanabe, Hitoshi; Inaba, Yuka; Kimura, Kumi; Asahara, Shun-Ichiro; Kido, Yoshiaki; Matsumoto, Michihiro; Motoyama, Takayasu; Tachibana, Nobuhiko; Kaneko, Shuichi; Kohno, Mitsutaka; Inoue, Hiroshi

2017-01-01

As the prevalence of nonalcoholic fatty liver disease (NAFLD), including steatosis and nonalcoholic steatohepatitis, is increasing, novel dietary approaches are required for the prevention and treatment of NAFLD. We evaluated the potential of mung bean protein isolate (MuPI) to prevent NAFLD progression. In Expts. 1 and 2, the hepatic triglyceride (TG) concentration was compared between 8-wk-old male mice fed a high-fat diet (61% of energy from fat) containing casein, MuPI, and soy protein isolate and an MuPI-constituent amino acid mixture as a source of amino acids (18% of energy) for 4 wk. In Expt. 3, hepatic fatty acid synthase (Fasn) expression was evaluated in 8-wk-old male Fasn-promoter-reporter mice fed a casein- or MuPI-containing high-fat diet for 20 wk. In Expt. 4, hepatic fibrosis was examined in 8-wk-old male mice fed an atherogenic diet (61% of energy from fat, containing 1.3 g cholesterol/100 g diet) containing casein or MuPI (18% of energy) as a protein source for 20 wk. In the high fat-diet mice, the hepatic TG concentration in the MuPI group decreased by 66% and 47% in Expt. 1 compared with the casein group (P hepatic TG concentration were lower in the MuPI group than in those fed casein (P hepatic fibrosis was not induced in the MuPI group, whereas it developed overtly in the casein group. MuPI potently reduced hepatic lipid accumulation in mice and may be a potential foodstuff to prevent NAFLD onset and progression. © 2017 American Society for Nutrition.

Clinical experience with infliximab therapy in 100 patients with Crohn's disease.

Science.gov (United States)

Farrell, R J; Shah, S A; Lodhavia, P J; Alsahli, M; Falchuk, K R; Michetti, P; Peppercorn, M A

2000-12-01

The aim of this study was to assess our clinical experience with infliximab, a monoclonal antitumor necrosis factor antibody, following its approval for treatment of refractory Crohn's disease (CD). We followed 100 consecutive patients with CD (53 women and 47 men; mean age, 41 yr) who received a total of 233 infliximab (5 mg/kg) infusions. Adverse events were noted and clinical response assessed every 2 wk for 6 months after each infusion using the Harvey Bradshaw Index (HBI) for active disease, the Perianal Disease Activity Index (PDAI) for fistulous disease, and steroid withdrawal rates for steroid-sparing efficacy. Indications for therapy were active disease (n = 57), perianal fistulous disease (n = 33), and steroid dependency (n = 10). Significant infusion reactions occurred in 16 patients (6.9% of infusions) including anaphylactic shock in one patient. Fourteen patients experienced infectious adverse events, 13 of whom were on concurrent steroids. Sixty percent of patients with active disease experienced > or = 50% HBI reduction at 2 wk; mean duration of response, 8.2 wk. Three of 26 first-time nonresponders with active disease (12%) responded to a second infusion. Sixty-nine percent of patients with fistulous disease experienced >50% reduction in their PDAI at 2 wk; mean duration of response, 10.9 wk. Four of 10 steroid-dependent patients (40%) discontinued steroid therapy, one of whom recommenced steroid therapy at 24 wk. Our clinical response rates mirror the efficacy reported in the controlled trials for active and fistulous disease. Steroid-sparing efficacy was seen in 40% of steroid-dependent patients. Concurrent steroids did not reduce the risk of significant infusion reactions (6.9%), but did increase the risk of infections.

Beneficial effects of benzodiazepine diazepam on chronic stress-induced impairment of hippocampal structural plasticity and depression-like behavior in mice.

Science.gov (United States)

Zhao, Yunan; Wang, Zhongli; Dai, Jianguo; Chen, Lin; Huang, Yufang; Zhan, Zhen

2012-03-17

Whether benzodiazepines (BZDs) have beneficial effects on the progress of chronic stress-induced impairment of hippocampal structural plasticity and major depression is uncertain. The present study designed four preclinical experiments to determine the effects of BZDs using chronic unpredictable stress model. In Experiment 1, several time course studies on behavior and hippocampus response to stress were conducted using the forced swim and tail suspension tests (FST and TST) as well as hippocampal structural plasticity markers. Chronic stress induced depression-like behavior in the FST and TST as well as decreased hippocampal structural plasticity that returned to normal within 3 wk. In Experiment 2, mice received p.o. administration of three diazepam dosages prior to each variate stress session for 4 wk. This treatment significantly antagonized the elevation of stress-induced corticosterone levels. Only low- (0.5mg/kg) and medium-dose (1mg/kg) diazepam blocked the detrimental effects of chronic stress. In Experiment 3, after 7 wk of stress sessions, daily p.o. diazepam administration during 1 wk recovery phase dose-dependently accelerated the recovery of stressed mice. In Experiment 4, 1 wk diazepam administration to control mice enhanced significantly hippocampal structural plasticity and induced an antidepressant-like behavioral effect, whereas 4 wk diazepam administration produced opposite effects. Hence, diazepam can slow the progress of chronic stress-induced detrimental consequences by normalizing glucocorticoid hormones. Considering the adverse effect of long-term diazepam administration on hippocampal plasticity, the preventive effects of diazepam may depend on the proper dose. Short-term diazepam treatment enhances hippocampal structural plasticity and is beneficial to recovery following chronic stress. Copyright © 2011 Elsevier B.V. All rights reserved.

A unique rodent model of cardiometabolic risk associated with the metabolic syndrome and polycystic ovary syndrome.

Science.gov (United States)

Shi, Danni; Dyck, Michael K; Uwiera, Richard R E; Russell, Jim C; Proctor, Spencer D; Vine, Donna F

2009-09-01

Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, oligo-/anovulation, and polycystic ovarian morphology and is a complex endocrine disorder that also presents with features of the metabolic syndrome, including obesity, insulin resistance, and dyslipidemia. These latter symptoms form cardiometabolic risk factors predisposing individuals to the development of type 2 diabetes and cardiovascular disease (CVD). To date, animal models to study PCOS in the context of the metabolic syndrome and CVD risk have been lacking. The aim of this study was to investigate the JCR:LA-cp rodent as an animal model of PCOS associated with the metabolic syndrome. Metabolic indices were measured at 6 and 12 wk, and reproductive parameters including ovarian morphology and estrous cyclicity were assessed at 12 wk or adulthood. At 6 wk of age, the cp/cp genotype of the JCR:LA-cp strain developed visceral obesity, insulin resistance, and dyslipidemia (hypertriglyceridemia and hypercholesterolemia) compared with control animals. Serum testosterone concentrations were not significantly different between groups at 6 wk of age. However, at 12 wk, the cp/cp genotype had higher serum testosterone concentrations, compared with control animals, and presented with oligoovulation, a decreased number of corpora lutea, and an increased number of total follicles, in particular atretic and cystic follicles. The cardiometabolic risk factors in the cp/cp animals were exacerbated at 12 wk including obesity, insulin resistance, and dyslipidemia. The results of this study demonstrate that the JCR:LA-cp rodent may be a useful PCOS-like model to study early mechanisms involved in the etiology of cardiometabolic risk factors in the context of both PCOS and the metabolic syndrome.

Tendon collagen synthesis declines with immobilization in elderly humans

DEFF Research Database (Denmark)

Dideriksen, Kasper; Boesen, Anders P; Reitelseder, Søren

2017-01-01

-80 yr) were randomly assigned to NSAIDs (ibuprofen 1,200 mg/day; Ibu) or placebo (Plc). One lower limb was immobilized in a cast for 2 wk and retrained for 6 wk. Tendon collagen protein synthesis, mechanical properties, size, expression of genes related to collagen turnover and remodeling, and signal...... intensity (from magnetic resonance imaging) were investigated. Tendon collagen synthesis decreased (P ... immobilization in both groups, whereas scleraxis mRNA decreased with inactivity in the Plc group only (P collagen protein synthesis decreased after 2 wk of immobilization, whereas tendon stiffness and modulus were only marginally reduced, and NSAIDs had no influence upon this...

Interactive effects of age and exercise on adiposity measures of41,582 physically active women

Energy Technology Data Exchange (ETDEWEB)

Williams, Paul T.; Satariano William A.

2004-06-01

The objective of this report is to assess in women whether exercise affects the estimated age-related increase in adiposity, and contrariwise, whether age affects the estimated exercise-related decrease in adiposity. Cross-sectional analyses of 64,911 female runners who provided data on their body mass index (97.6 percent), waist (91.1percent), and chest circumferences (77.9 percent). Age affected the relationships between vigorous exercise and adiposity. The decline in BMI per km/wk run was linear in 18-25 year olds (-0.023+-0.002 kg/m2 perkm run) and became increasingly nonlinear (convex or upwardly concave) with age. The waist, hip and chest circumferences declined significantly with running distance across all age groups, but the declines were 52-58 percent greater in older than younger women (P<10-5). The relationships between body circumferences and running distance became increasingly convexity (upward concavity) in older women. Conversely, vigorous exercise diminished the apparent increase in adiposity with age. The rise in average BMI with age was greatest in women who ran less than 8 km/week (0.065+-0.005 kg/m2 per y), intermediate of women who ran 8-16km/wk (0.025+-0.004kg/m2 per y) or 16-32 km/wk (0.022+-0.003 kg/m2 pery), and least in those who averaged over 32 km/wk (0.017+-0.001 kg/m2 pery). Before age 45, waist circumference rose 0.055+-0.026 cm in for those who ran 0-8 km/wk, showed no significant change for those who ran 8-40km./wk, and declined -0.057+-0.012 and -0.069+-0.014 cm per year in those who ran 40 -56 and over 56 km/wk. The rise in hip and chest circumferences with age were significantly greater in women who ran under eight km/wk than longer distance runners for hip (0.231+-0.018 vs0.136+-0.004 cm/year) and chest circumferences (0.137+-0.013 vs0.053+-0.003 cm/year). These cross-sectional associations suggest that in women, age and vigorous exercise interact with each other in affecting adiposity. The extent that these cross

Whole Grain Compared with Refined Wheat Decreases the Percentage of Body Fat Following a 12-Week, Energy-Restricted Dietary Intervention in Postmenopausal Women

DEFF Research Database (Denmark)

Kristensen, Mette; Toubro, Søren; Jensen, Morten Georg

2012-01-01

) with whole-grain wheat (WW) for 12 wk on body weight and composition after a 2-wk run-in period of consumption of RW-containing food intake. In this open-label randomized trial, 79 overweight or obese postmenopausal women were randomized to an energy-restricted diet (deficit of approximately 1250 k...

Ambush marketing grote bedreiging voor sportevents

NARCIS (Netherlands)

Slender, Hans

2010-01-01

De marketeers van Bavaria hebben natuurlijk goud in handen. Het begon met een flashmob op de tribune tijdens de voorbereiding van het Nederlands elftal, maar tijdens het WK groeide de ‘Dutch Dress’ uit tot de meest geslaagde marketingactie van het afgelopen WK. Het zal dan ook niemand verbazen dat

La bandera de la cienc;a y del arte

Directory of Open Access Journals (Sweden)

Manuel José Luque

1947-01-01

Full Text Available El Dr. Miguel Becerro de Bengoa, prestigioso cancerólogo y Director del "Boletín de lucha contra el cáncer", de Montevideo, a poco de fallecer el profesor americano Howard Kelly publicó estas palabras : "Nos inclinamos reverentes ante su desaparición y ponemos en nuestra casa, a media asta, la bandera universal de la ciencia".

76 FR 13130 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

Science.gov (United States)

2011-03-10

.... SUPPLEMENTARY INFORMATION: Background Sections 101(a)(5)(A) and (D) of the MMPA (16 U.S.C. 1361 et seq.) direct... , respectively. The ringed seal status review report by Kelly et al. (2010) can be found on the Internet at: http... acoustic and non-acoustic effects. It is uncertain if the seals react to the sound of the helicopter or to...

Passage Key Inlet, Florida; CMS Modeling and Borrow Site Impact Analysis

Science.gov (United States)

2016-06-01

Impact Analysis by Kelly R. Legault and Sirisha Rayaprolu PURPOSE: This Coastal and Hydraulics Engineering Technical Note (CHETN) describes the...driven sediment transport at Passage Key Inlet. This analysis resulted in issuing a new Florida Department of Environmental Protection (FDEP) permit to...Funding for this study was provided by the USACE Regional Sediment Management (RSM) Program, a Navigation Research, Development, and Technology Portfolio

Community Colleges Mobilize to Train Cybersecurity Workers

Science.gov (United States)

Parry, Marc

2009-01-01

If you work at a community college that teaches cybersecurity, it pays to be located in the backyard of a spy agency. Just don't ask Kelly A. Koermer, administrator of the Anne Arundel Community College, what's inside those dark towers at Fort Meade. She points out other highlights of the restricted region: an employees-only exit off the highway,…

From third degree to third generation interrogation strategies: putting science into the art of criminal interviewing

Science.gov (United States)

2017-03-01

tacitly suggest that a confession is the fastest and best way to end the interrogation .73 71 Ibid...Kelly, and Miller found approximately 45 percent of civilian interrogators use it as well.292 Because this percentage suggests the technique is...TO THIRD-GENERATION INTERROGATION STRATEGIES: PUTTING SCIENCE INTO THE ART OF CRIMINAL INTERVIEWING by Desmond S. O’Neill March 2017

System Architecture of Small Unmanned Aerial System for Flight Beyond Visual Line-of-Sight

Science.gov (United States)

2015-09-17

International Conference on Mechatronic and Embedded Systems and Applications (MESA 2011), 28-31 (August 2011) Maddalon Jeffrey M., Kelly J... SYSTEM ARCHITECTURE OF SMALL UNMANNED AERIAL SYSTEM FOR FLIGHT BEYOND VISUAL LINE-OF-SIGHT THESIS...is declared a work of the U.S. Government and is not subject to copyright protection in the United States. AFIT-ENV-MS-15-S-047 SYSTEM

Conference on Stochastic Processes and their Applications (16th) Held in Stanford, California on August 17-21, 1987.

Science.gov (United States)

1987-08-01

ESTIMATION FOR STOCHASTIC PROCESSES by C. C. Heyde Australian National University Canberra, Australia ABSTRACT Optimality is a widely and loosely used...Case 240 S. Australia 1211 Geneva 24 Switzerland Christopher C. Heyde Dept. of Statistics, IAS Patricia Jacobs . Australian National University...Universitat Regensburg USA Postfach D-8400 Regensburg Anatole Joffe W. Germany Dept. of Mathematics & Statatistics Frank Kelly Universite de Montreal

ISSN 2073-9990 East Cent. Afr. J. surg

African Journals Online (AJOL)

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especially between 5 and 7years because fusion of the distal humeral physis peaks at age six.3 There are two major types of supracondylar humerus fractures extension (95% of cases) and flexion (5% of cases)1,2. While different ..... P.J. Walmsley, H.B. Kelly, J.E. Robb, I.H. Annan, D.E. Porter. Delay increases the need for.

La bandera de la cienc;a y del arte

OpenAIRE

Luque, Manuel José

2012-01-01

El Dr. Miguel Becerro de Bengoa, prestigioso cancerólogo y Director del "Boletín de lucha contra el cáncer", de Montevideo, a poco de fallecer el profesor americano Howard Kelly publicó estas palabras : "Nos inclinamos reverentes ante su desaparición y ponemos en nuestra casa, a media asta, la bandera universal de la ciencia".

Changes of tear film after LASIK with corneal flap created by femtosecond laser and microkeratome

Directory of Open Access Journals (Sweden)

Yuan Zhang

2014-09-01

Full Text Available AIM: To observe the changes of tear film on the patients after laser in situ keratomileusis(LASIKwith corneal flap created by femtosecond laser and microkeratome.METHODS: Totally 150 patients(300 eyeswith myopia received operation of LASIK. Patients were divided into two groups according to the methods of making corneal flap. The patients of group one were assigned to receiving LASIK with corneal flap creation by Intralase femtosecond laser(190 eyes of 95 patients, group two were assigned to receiving LASIK with corneal flap creation by microkeratome(110 eyes of 55 patients. Dry eye symptom score, tear break-up time(BUT, Schirmer Ⅰ test(S I t, corneal fluorescein staining(FLwere recorded preoperatively and postoperatively at 1wk; 1, 3 and 6mo. RESULTS: Dry eye symptom score: there existed obvious differences at 1wk; 1, 3mo between two groups(PP>0.05. BUT: there existed obvious differences at 1wk, 1, 3mo between two groups(PP>0.05. SchirmerⅠ test: there existed obvious differences in the 1wk, 1, 3mo between two groups(PP>0.05. FL: there existed obvious differences in the 1wk, 1, 3mo between two groups(PP>0.05.CONCLUSION: The early stability of tear film decrease after operation in both of the two groups. The dry eye symptoms are lighter and recover faster.

Efficacy of antimicrobial pullulan-based coating to improve internal quality and shelf-life of chicken eggs during storage.

Science.gov (United States)

Morsy, Mohamed K; Sharoba, Ashraf M; Khalaf, Hassan H; El-Tanahy, Hassan H; Cutter, Catherine N

2015-05-01

There has been a growing interest in the use of natural materials as a delivery mechanism for antimicrobials and coatings in foods. The aim of the present study was to evaluate the effectiveness of pullulan coatings to improve internal quality and shelf-life of fresh eggs during 10 wk of storage at 25 and 4 °C. Three treatments of eggs were evaluated as follows; non-coated (control; C), coated with pullulan (P), and coated with pullulan containing nisin (N). The effects of the pullulan coatings on microbiological qualities, physical properties, and freshness parameters were investigated and compared with non-coated eggs. For non-coated eggs, as storage time increased, yolk index, albumen index, and Haugh unit value decreased and weight loss increased. However, pullulan coatings (P or N) minimized weight loss (eggs (with a final B grade) 3 wk longer than non-coated eggs at 25 °C. At 4 °C, both P- and N-coated eggs went from AA to A grade after 9 wk and maintained the grade for 10 wk (4 wk longer than that of non-coated eggs). This study is the first to demonstrate that pullulan coatings can preserve the internal quality, prolong the shelf-life, and minimize weight loss of fresh eggs. © 2015 Institute of Food Technologists®

High dietary fat intake during lactation promotes development of diet-induced obesity in male offspring of mice.

Science.gov (United States)

Tsuduki, Tsuyoshi; Kitano, Yasuna; Honma, Taro; Kijima, Ryo; Ikeda, Ikuo

2013-01-01

The maternal nutritional status during pregnancy and lactation influences the risk of obesity in offspring, but the details of this phenomenon are unclear. In particular, there is little information on the influence on the offspring of the maternal nutritional status during lactation only. Therefore, in this study, we examined the influence of high dietary fat intake in dams during lactation on the risk of obesity in offspring, using C57BL/6J mice. The mice were fed a control diet (CD) during pregnancy. After birth, dams were fed a CD or a high-fat diet (HD) during lactation (3 wk). Fat and energy were significantly increased in milk from dams fed a HD during lactation. Male offspring were weaned at 3 wk old and fed a CD for 4 wk, which resulted in no significant difference in their physique. Four weeks after weaning, the offspring (7 wk old) were fed a CD or HD for 4 wk to induce obesity. High dietary fat intake in dams and offspring promoted lipid accumulation in white adipose tissue and adipocyte hypertrophy in male offspring. The underlying mechanism may involve an increase in expression of Lpl and a decrease in expression of Hsl in white adipose tissue of offspring. In conclusion, our results show that high dietary fat intake during lactation promotes development of diet-induced obesity in male offspring.

Rapid elimination of field colonies of subterranean termites (Isoptera: Rhinotermitidae) using bistrifluron solid bait pellets.

Science.gov (United States)

Evans, Theodore A

2010-04-01

The efficacy of bistrifluron, a chitin synthesis inhibitor, in cellulose bait pellets was evaluated on the mound-building subterranean termite, Coptotermes acinaciformis (Froggatt). Three concentrations of the bistrifluron were used: 0 (untreated control), 0.5, and 1.0% over an 8 wk period. Both doses of bistrifluron bait eliminated (viz. termites absent from nest or mound) termite colonies: 83% of colonies (10 of 12) were either eliminated or moribund (viz. colony had no reproductive capacity and decreased workforce) after 8 wk, compared with none of the control colonies. The remaining two treated colonies were deemed to be in decline. Early signs that bistrifluron was affecting the colonies included: 3 wk after baiting mound temperatures showed a loss of metabolic heat, 4 wk after baiting foraging activity in feeding stations was reduced or absent, and dissection of two mounds at 4 wk showed they were moribund. Colony elimination was achieved in around half or less the time, and with less bait toxicant, than other bait products tested under similar conditions in the field, because of either the active ingredient, the high surface area of the pellets, or a combination of both. This suggests the sometimes long times reported for control using baits may be reduced significantly. The use of a mound building species demonstrated clearly colony level effects before and after termites stopped foraging in bait stations.

Wasabia japonica is a potential functional food to prevent colitis via inhibiting the NF-κB signaling pathway.

Science.gov (United States)

Kang, Ju-Hee; Choi, Seungho; Jang, Jeong-Eun; Ramalingam, Prakash; Ko, Young Tag; Kim, Sun Yeou; Oh, Seung Hyun

2017-08-01

Inflammatory bowel diseases (IBDs), including Crohn's disease (CD) and ulcerative colitis (UC), are prevalent and debilitating health problems worldwide. Many types of drugs are used to treat IBDs, but they exhibit adverse effects such as vomiting, nausea, abdominal pain, diarrhea, etc. In order to overcome the limitations of current therapeutic drugs, scientists have searched for functional foods from natural resources. In this study, we investigated the anti-colitic effects of Wasabia japonica extract in a DSS-induced colitis model. Wasabi japonica is a plant of the Brassicaceae family that has recently been reported to exhibit properties of detoxification, anti-inflammation, and induction of apoptosis in cancer cells. In this study, we generated wasabi ethanol extract (WK) and assessed its anti-colitic effect. In addition, in order to improve delivery of the extract to the colon, WK was coated with 5% Eudragit S100 (WKE), after which the anti-colitic effects of WKE were assessed. In conclusion, WK prevented development of colitis through inhibition of the NF-kB signaling pathway and recovery of epithelial tight junctions. In addition, the anti-colitic effect of WK was enhanced by improving its delivery to the colon by coating the WK with Eudragit S100. Therefore, we suggest that wasabi can be used as a new functional food to prevent IBDs due to its anti-colitic effect.

Comparison of percutaneous electrical nerve stimulation with transcutaneous electrical nerve stimulation for long-term pain relief in patients with chronic low back pain.

Science.gov (United States)

Yokoyama, Masataka; Sun, Xiaohui; Oku, Satoru; Taga, Naoyuki; Sato, Kenji; Mizobuchi, Satoshi; Takahashi, Toru; Morita, Kiyoshi

2004-06-01

The long-term effect of percutaneous electrical nerve stimulation (PENS) on chronic low back pain (LBP) is unclear. We evaluated the number of sessions for which PENS should be performed to alleviate chronic LBP and how long analgesia is sustained. Patients underwent treatment on a twice-weekly schedule for 8 wk. Group A (n = 18) received PENS for 8 wk, group B (n = 17) received PENS for the first 4 wk and transcutaneous electrical nerve stimulation (TENS) for the second 4 wk, and group C (n = 18) received TENS for 8 wk. Pain level, degree of physical impairment, and the daily intake of nonsteroidal antiinflammatory drugs (NSAIDs) were assessed before the first treatment, 3 days after Week 2, Week 4, and Week 8 treatments, and at 1 and 2 mo after the sessions. During PENS therapy, the pain level decreased significantly from Week 2 in Groups A and B (P pain level decreased significantly only at Week 8 (P TENS for chronic LBP but must be continued to sustain the analgesic effect. A cumulative analgesic effect was observed in patients with chronic low back pain (LBP) after repeated percutaneous electrical nerve stimulation (PENS), but this effect gradually faded after the treatment was terminated. Results indicate that although PENS is effective for chronic LBP, treatments need to be continued to sustain analgesia.

Implementasi Ruhul Islam terhadap Pembentukan Karakter Mahasiswa di Perguruan Tinggi Berbasis Islam dan Teknologi Informasi

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Mochamad Malik Akbar Rohandi

2017-11-01

Full Text Available Ruhul Islam is the core spirit of Islam that is the identity or characteristic of an individual or Islamic institution that has a mental attitude. It always guided by morals, according to the guidance of Islamic teachings so that can create a brotherhood of fellow Muslims in bringing people to a better state. The objective of this research is to know the comparison of Ruhul Islam application level to the embedded character in college student based on Islam and technology. Explanatory research method used primary data of field observation and questionnaire and secondary data, sample using Slovin formula and purposive sampling method with error rate of 10%, interconnection between variables using path analysis. Characteristics of respondents majority of women, active age 18-21 year students, high school graduates and the origin of UNISBA students 67% of Bandung while Telkom 82% outside Bandung. Implementation of Islamic values ​​with character formation in Islamic universities has a stronger relationship than information technology-based colleges with a R2 level of 37% versus 32.8%, more than 60% character formation can be influenced by other factors or variables.

Pengaruh strategi pemasaran terhadap kepuasan konsumen pada jasa persewaan buku kotaro Kota Madiun

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Ryan Aikas Priono Arianto

2017-01-01

Full Text Available This study aims to determine the marketing strategy to customer satisfaction in the town of Madiun, to determine customer satisfaction in the book rental services Kotaro Madiun, to determine customer satisfaction in the book rental services Kotarodi Madiun. The samples in this study using a random sampling of 100 consumers renting libraries Slovin Kotaro formula obtained 46 samples. Collecting data using the method of documentation and questionnaires. To test the validity of data to test the validity and reliability. The questionnaire that has been deployed processed using IJI correlations and Cronbach alpha, while the hypothesis using simple linear regression and processed using SPSS 1.6. for windows. The results showed that marketing strategies have relationships and a positive effect on customer satisfaction in the book rental services Kotaro Madiun. T test obtained t value of 6.853 with sig 0,000 while ttab at the level of 0.05 at 1.684. It can be said thit > ttab (6.853 > 1.684 or Sighit < Sigprob (0.000 < 0.05 this situation is no different do can influence marketing strategies to customer satisfaction in the book rental services Kotaro Madiun.

Analisis Dampak Penerapan IT Service Desk pada Bank XYZ

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Ario Adi Prasetyo

2010-12-01

Full Text Available The purpose of this study is to identify the determinants of IT operational performance related to IT Service Desk. And to determine the consideration of implementing IT Service Desk in the company business processes. The population in this study is 1500 employees or users of the IT Service Desk service. By using the Slovin, 100 users were obtained in the sample. The variables in this study include success factors of IT Service Desk and Problem Management. Methods of data collection include using questionnaire s. Analysis of data is conducted using multivariate analysis of the factor analysis. The conclusions of this research is obtained from, among others, the factors of success of the IT Service Desk and Problem Management. There are 9 to 37 variables and indicators. From the research, it is found that there is a relationship between factors. And after the reduction process of 37 indicators four new factors was formed which consist of a quick solution factor, excellent IT Service Desk factor, focus support factor, and excellent staff factor. From all the new factors, quick solution is the most dominant factor. 

THE INFLUENCE OF PARTICIPATIVE LEADERSHIP STYLE OF COMMUNITY RELATIONS OFFICER PT. HOLCIM INDONESIA TBK. CILACAP-PLANT ON THE PERFORMANCE OF POSDAYA COMMUNITIES IN SUB-DISTRIC OF NORTH CILACAP

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Riyas Anggun Putri Cahyani

2016-09-01

form empowerment of local communities, that is Posdaya (Family Empowerment Program. This study aims to examine and analyze the influence of participative leadership style of the Community Relations Officer (CRO PT. Holcim Indonesia Tbk Cilacap - Plant toward Posdaya (Family Empowerment Centre in North Cilacap. This study uses quantitative methods and the data collected by the distribution of questionnaires which consist as 96 samples. It was measured by using slovin formulate with a degree of error is 5 % for 126 communities. The research was used proportional sampling as a sampling technique and analyzed by SPSS for windows 16.00, include validity and reliability tests to examine the questionnaires. t-test, F-test and coefficient of determination (R2 were the part of a simple regression analysis to prove the hypothesis of the research. Based on the data analysis, the simple linear regression equation is Y = 11.370 + 0,423X, its means that there was a linearly and positively influence of participative leadership style on the performance of Posdaya communities. The conclusion is if participative leadership style of the CRO is increased, the performance of Posdaya will also increase.

Effects of lighting pattern and photoperiod on egg production and egg quality of a native chicken under free-range condition.

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Geng, A L; Zhang, Y; Zhang, J; Wang, H H; Chu, Q; Liu, H G

2018-04-14

The paper aimed to study the effects of lighting pattern and photoperiod alone and in combination on egg production, egg quality in Beijing You Chicken (BYC). A total of 630 19-wk-old BYC laying hens were randomly allocated to 6 groups with 105 birds each, 3 replicates per group, reared in individually lit floor pens with separate outdoor areas. A 2 × 3 factorial experiment (2 lighting patterns: continuous and intermittent lighting; 3 photoperiods: 16, 14, 12 h) was arranged, including 16L:8D (6:00 to 22:00) for group 1; 12L:2D:4L:6D (6:00 to 18:00, 20:00 to 24:00) for group 2; 14L:10D (6:00 to 20:00) for group 3; 10L:2D:4L:8D (6:00 to 16:00, 18:00 to 22:00) for group 4; 12L:12D (6:00 to 18:00) for group 5, and 8L:4D:4L:8D (6:00 to 14:00, 18:00 to 22:00) for group 6, respectively. Egg production parameters were calculated for 22 to 43, 44 to 57, and 22 to 57 wk, and egg quality parameters were measured at the end of 37 and 57 wk. The results showed that the egg production of BYC was not significantly affected by lighting pattern, photoperiod alone, or in combination during 22 to 43 and 22 to 57 wk (P > 0.05), but average feed intake in 12 h groups was significantly higher than those in 14 and 16 h groups during 22 to 43 and 22 to 57 wk (P Egg mass and feed egg ratio were significantly affected by lighting pattern, photoperiod alone, and in combination during 44 to 57 wk (P Egg mass was significantly higher (P = 0.05) and feed egg ratio was significantly lower (P = 0.03) in continuous groups than in intermittent groups. There were significant effects for eggshell thickness, albumen height, haugh unit, and egg grade by lighting pattern alone (P egg production was not significantly affected by lighting pattern alone during 22 to 57 wk (P > 0.05), but the photoperiod significantly affected average feed intake (P egg production during 44 to 57 wk, and intermittent lighting is better for egg quality of the native bird at 37 wk; 3) 12 h lighting is enough for meeting

Ministeeriumi kantslerid tegid kohtumisel 25 000-eurose mürtsu / Kelli Seiton

Index Scriptorium Estoniae

Seiton, Kelli

2013-01-01

Kaitseministeeriumi korraldatud erinevate ministeeriumite kantslerite kokkusaamisest, mille käigus viidi kaitseväe keskpolügoonil läbi näidislaskmine ning lasti õhku tankitõrjerakett Milan 2, mille maksumus on väidetavalt 25 000 eurot

Change in Neutrophil-to-lymphocyte Ratio in Response to Targeted Therapy for Metastatic Renal Cell Carcinoma as a Prognosticator and Biomarker of Efficacy

DEFF Research Database (Denmark)

Templeton, Arnoud J; Knox, Jennifer J; Lin, Xun

2016-01-01

at baseline and 6 (± 2) wk later. A landmark analysis at 8 wk was conducted to explore the prognostic value of relative NLR change on overall survival (OS), progression-free survival (PFS), and objective response rate using Cox or logistic regression models, adjusted for variables in IMDC score and NLR values...

Nitrate but not tea saponin feed additives decreased enteric methane emissions in nonlactating cows.

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Guyader, J; Eugène, M; Doreau, M; Morgavi, D P; Gérard, C; Loncke, C; Martin, C

2015-11-01

Tea saponin is considered a promising natural compound for reducing enteric methane emissions in ruminants. A trial was conducted to study the effect of this plant extract fed alone or in combination with nitrate on methane emissions, total tract digestive processes, and ruminal characteristics in cattle. The experiment was conducted as a 2 × 2 factorial design with 4 ruminally cannulated nonlactating dairy cows. Feed offer was restricted to 90% of voluntary intake and diets consisted of (DM basis): 1) control (CON; 50% hay and 50% pelleted concentrates), 2) CON with 0.5% tea saponin (TEA), 3) CON with 2.3% nitrate (NIT), and 4) CON with 0.5% tea saponin and 2.3% nitrate (TEA+NIT). Tea saponin and nitrate were included in pelleted concentrates. Diets contained similar amounts of CP (12.2%), starch (26.0%), and NDF (40.1%). Experimental periods lasted 5 wk including 2 wk of measurement (wk 4 and 5), during which intake was measured daily. In wk 4, daily methane emissions were quantified for 4 d using open circuit respiratory chambers. In wk 5, total tract digestibility, N balance, and urinary excretion of purine derivatives were determined from total feces and urine collected separately for 6 d. Ruminal fermentation products and protozoa concentration were analyzed from samples taken after morning feeding for 2 nonconsecutive days in wk 5. Tea saponin and nitrate supplementation decreased feed intake ( saponin did not modify methane emissions (g/kg DMI; > 0.05), whereas nitrate-containing diets (NIT and TEA+NIT) decreased methanogenesis by 28%, on average ( saponin, whereas nitrate-containing diets increased acetate proportion and decreased butyrate proportion and ammonia concentration ( saponin alone included in pelleted concentrates failed to decrease enteric methane emissions in nonlactating dairy cows.

Asymptomatic bacteriuria & obstetric outcome following treatment in early versus late pregnancy in north Indian women.

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Jain, Vaishali; Das, Vinita; Agarwal, Anjoo; Pandey, Amita

2013-04-01

Asymptomatic bacteriuria during pregnancy if left untreated, may lead to acute pyelonephritis, preterm labour, low birth weight foetus, etc. Adequate and early treatment reduces the incidence of these obstetric complications. The present study was done to determine presence of asymptomatic bacteriuria (ASB) and obstetric outcome following treatment in early versus late pregnancy. A prospective cohort study was conducted at a tertiary care teaching hospital of north India. Pregnant women till 20 wk (n=371) and between 32 to 34 wk gestation (n=274) having no urinary complaints were included. Their mid stream urine sample was sent for culture and sensitivity. Women having > 10 [5] colony forming units/ml of single organism were diagnosed positive for ASB and treated. They were followed till delivery for obstetric outcome. Relative risk with 95% confidence interval was used to describe association between ASB and outcome of interest. ASB was found in 17 per cent pregnant women till 20 wk and in 16 per cent between 32 to 34 wk gestation. Increased incidence of preeclamptic toxaemia (PET) [RR 3.79, 95% CI 1.80-7.97], preterm premature rupture of membrane (PPROM)[RR 3.63, 45% CI 1.63-8.07], preterm labour (PTL) [RR 3.27, 95% CI 1.38-7.72], intrauterine growth restriction (IUGR)[RR 3.79, 95% CI 1.80-79], low birth weight (LBW) [RR1.37, 95% CI 0.71-2.61] was seen in late detected women (32-34 wk) as compared to ASB negative women, whereas no significant difference was seen in early detected women (till 20 wk) as compared to ASB negative women. Early detection and treatment of ASB during pregnancy prevents complications like PET, IUGR, PTL, PPROM and LBW. Therefore, screening and treatment of ASB may be incorporated as routine antenatal care for safe motherhood and healthy newborn.

Asymptomatic bacteriuria & obstetric outcome following treatment in early versus late pregnancy in north Indian women

Science.gov (United States)

Jain, Vaishali; Das, Vinita; Agarwal, Anjoo; Pandey, Amita

2013-01-01

Background & objectives: Asymptomatic bacteriuria during pregnancy if left untreated, may lead to acute pyelonephritis, preterm labour, low birth weight foetus, etc. Adequate and early treatment reduces the incidence of these obstetric complications. The present study was done to determine presence of asymptomatic bacteriuria (ASB) and obstetric outcome following treatment in early versus late pregnancy. Methods: A prospective cohort study was conducted at a tertiary care teaching hospital of north India. Pregnant women till 20 wk (n=371) and between 32 to 34 wk gestation (n=274) having no urinary complaints were included. Their mid stream urine sample was sent for culture and sensitivity. Women having > 105 colony forming units/ml of single organism were diagnosed positive for ASB and treated. They were followed till delivery for obstetric outcome. Relative risk with 95% confidence interval was used to describe association between ASB and outcome of interest. Results: ASB was found in 17 per cent pregnant women till 20 wk and in 16 per cent between 32 to 34 wk gestation. Increased incidence of preeclamptic toxaemia (PET) [RR 3.79, 95% CI 1.80-7.97], preterm premature rupture of membrane (PPROM)[RR 3.63, 45% CI 1.63-8.07], preterm labour (PTL) [RR 3.27, 95% CI 1.38-7.72], intrauterine growth restriction (IUGR)[RR 3.79, 95% CI 1.80-79], low birth weight (LBW) [RR1.37, 95% CI 0.71-2.61] was seen in late detected women (32-34 wk) as compared to ASB negative women, whereas no significant difference was seen in early detected women (till 20 wk) as compared to ASB negative women. Interpretation & conclusions: Early detection and treatment of ASB during pregnancy prevents complications like PET, IUGR, PTL, PPROM and LBW. Therefore, screening and treatment of ASB may be incorporated as routine antenatal care for safe motherhood and healthy newborn. PMID:23703344

Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus1234

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Norris, Leigh E; Collene, Angela L; Asp, Michelle L; Hsu, Jason C; Liu, Li-Fen; Richardson, Julia R; Li, Dongmei; Bell, Doris; Osei, Kwame; Jackson, Rebecca D

2009-01-01

Background: Weight loss may improve glucose control in persons with type 2 diabetes. The effects of fat quality, as opposed to quantity, on weight loss are not well understood. Objective: We compared the effects of 2 dietary oils, conjugated linoleic acid (CLA) and safflower oil (SAF), on body weight and composition in obese postmenopausal women with type 2 diabetes. Design: This was a 36-wk randomized, double-masked, crossover study. Fifty-five obese postmenopausal women with type 2 diabetes received SAF or CLA (8 g oil/d) during two 16-wk diet periods separated by a 4-wk washout period. Subjects met monthly with the study coordinator to receive new supplements and for assessment of energy balance, biochemical endpoints, or anthropometric variables. Results: Thirty-five women completed the 36-wk intervention. Supplementation with CLA reduced body mass index (BMI) (P = 0.0022) and total adipose mass (P = 0.0187) without altering lean mass. The effect of CLA in lowering BMI was detected during the last 8 wk of each 16-wk diet period. In contrast, SAF had no effect on BMI or total adipose mass but reduced trunk adipose mass (P = 0.0422) and increased lean mass (P = 0.0432). SAF also significantly lowered fasting glucose (P = 0.0343) and increased adiponectin (P = 0.0051). No differences were observed in dietary energy intake, total fat intake, and fat quality in either diet period for either intervention. Conclusions: Supplementation with CLA and SAF exerted different effects on BMI, total and trunk adipose mass, and lean tissue mass in obese postmenopausal women with type 2 diabetes. Supplementation with these dietary oils may be beneficial for weight loss, glycemic control, or both. PMID:19535429

DBA2J db/db mice are susceptible to early albuminuria and glomerulosclerosis that correlate with systemic insulin resistance.

Science.gov (United States)

Østergaard, Mette V; Pinto, Vanda; Stevenson, Kirsty; Worm, Jesper; Fink, Lisbeth N; Coward, Richard J M

2017-02-01

Diabetic nephropathy (DN) is the leading cause of kidney failure in the world. To understand important mechanisms underlying this condition, and to develop new therapies, good animal models are required. In mouse models of type 1 diabetes, the DBA/2J strain has been shown to be more susceptible to develop kidney disease than other common strains. We hypothesized this would also be the case in type 2 diabetes. We studied db/db and wild-type (wt) DBA/2J mice and compared these with the db/db BLKS/J mouse, which is currently the most widely used type 2 DN model. Mice were analyzed from age 6 to 12 wk for systemic insulin resistance, albuminuria, and glomerular histopathological and ultrastructural changes. Body weight and nonfasted blood glucose were increased by 8 wk in both genders, while systemic insulin resistance commenced by 6 wk in female and 8 wk in male db/db DBA/2J mice. The urinary albumin-to-creatinine ratio (ACR) was closely linked to systemic insulin resistance in both sexes and was increased ~50-fold by 12 wk of age in the db/db DBA/2J cohort. Glomerulosclerosis, foot process effacement, and glomerular basement membrane thickening were observed at 12 wk of age in db/db DBA/2J mice. Compared with db/db BLKS/J mice, db/db DBA/2J mice had significantly increased levels of urinary ACR, but similar glomerular histopathological and ultrastructural changes. The db/db DBA/2J mouse is a robust model of early-stage albuminuric DN, and its levels of albuminuria correlate closely with systemic insulin resistance. This mouse model will be helpful in defining early mechanisms of DN and ultimately the development of novel therapies. Copyright © 2017 the American Physiological Society.

Influence of host age on critical fitness parameters of Spathius galinae (Hymenoptera: Braconidae), a new parasitoid of the emerald ash borer (Coleoptera: Buprestidae).

Science.gov (United States)

Watt, Timothy J; Duan, Jian J

2014-08-01

Spathius galinae Belokobylskij and Strazenac (Hymenoptera: Braconidae) is a recently discovered gregarious idiobiont larval ectoparasitoid currently being evaluated for biological control against the invasive emerald ash borer, Agrilus planipennis Fairmaire (Coleoptera: Buprestidae) in the United States. To aid in the development of laboratory rearing protocols, we assessed the influence of various emerald ash borer stages on critical fitness parameters of S. galinae. We exposed gravid S. galinae females to emerald ash borer host larvae of various ages (3.5, 5, 7, and 10 wk post egg oviposition) that were reared naturally in tropical (evergreen) ash (Fraxinus uhdei (Wenzig) Lingelsh) logs, or to field-collected, late-stage emerald ash borers (nonfeeding J-shaped larvae termed "J-larvae," prepupae, and pupae) that were artificially inserted into green ash logs. When exposed to larvae in tropical ash logs, S. galinae attacked 5 and 7 wk hosts more frequently (68-76%) than 3.5 wk (23%) and 10 wk (12%) hosts. Subsample dissections of the these logs revealed that 3.5, 5, 7 and 10 wk host logs contained mostly second, third, fourth, and J-larvae, respectively, that had already bored into the sapwood for diapause. No J-larvae were attacked by S. galinae when naturally reared in tropical ash logs. When parasitized by S. galinae, 7 and 10 wk hosts produced the largest broods (approximately 6.7 offspring per parasitized host), and the progenies that emerged from these logs had larger anatomical measurements and more female-biased sex ratios. When exposed to emerald ash borer J-larvae, prepupae, or pupae artificially inserted into green ash logs, S. galinae attacked 53% ofJ-larvae, but did not attack any prepupae or pupae. We conclude that large (fourth instar) emerald ash borer larvae should be used to rear S. galinae.

Sex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood

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Conforto Tara L

2012-04-01

Full Text Available Abstract Background Early liver development and the transcriptional transitions during hepatogenesis are well characterized. However, gene expression changes during the late postnatal/pre-pubertal to young adulthood period are less well understood, especially with regards to sex-specific gene expression. Methods Microarray analysis of male and female mouse liver was carried out at 3, 4, and 8 wk of age to elucidate developmental changes in gene expression from the late postnatal/pre-pubertal period to young adulthood. Results A large number of sex-biased and sex-independent genes showed significant changes during this developmental period. Notably, sex-independent genes involved in cell cycle, chromosome condensation, and DNA replication were down regulated from 3 wk to 8 wk, while genes associated with metal ion binding, ion transport and kinase activity were up regulated. A majority of genes showing sex differential expression in adult liver did not display sex differences prior to puberty, at which time extensive changes in sex-specific gene expression were seen, primarily in males. Thus, in male liver, 76% of male-specific genes were up regulated and 47% of female-specific genes were down regulated from 3 to 8 wk of age, whereas in female liver 67% of sex-specific genes showed no significant change in expression. In both sexes, genes up regulated from 3 to 8 wk were significantly enriched (p p Ihh; female-specific Cdx4, Cux2, Tox, and Trim24 and may contribute to the developmental changes that lead to global acquisition of liver sex-specificity by 8 wk of age. Conclusions Overall, the observed changes in gene expression during postnatal liver development reflect the deceleration of liver growth and the induction of specialized liver functions, with widespread changes in sex-specific gene expression primarily occurring in male liver.

Utility of the whole-kidney and parenchymal time-activity curves for a prediction of diuretic response

International Nuclear Information System (INIS)

Samal, M.; Mostbeck, A.; Bergmann, H.; Nimmon, C.C.; Staudenherz, A.; Dudczak, R.

2002-01-01

Full text: In a retrospective study, MAG3 dynamic renal data (90 kidneys in 57 children) have been analyzed with the aim to test a prediction of diuretic response. Whole-kidney (WK) and parenchymal (PA) curves were extracted from 20 min pre-diuretic phase using standard and fuzzy ROIs. Peak time (PT), half time (HT), ratio of the curve value in 20th min to the curve maximum (RM), mean transit time (TT), and output efficiency (OE) were calculated for each curve. With PA curves, also the transit time index (PI) was calculated. The curve parameters were compared with the maximum elimination rate of urine after diuretic (EM) using paired correlation and Fisher's linear discriminate function. The highest correlation was found between ln EM and OE-PA (0.61), RM-PA (-0.58), TT-PA (-0.57), and PI (-0.57). Best diagnostic accuracy in prediction of EM ≤ 7 % (a sign of obstruction) was obtained with OE-PA (87 %), PI (87 %), and both PT-PA and RM-PA (83 %). Parameters of WK curves had higher sensitivity, those of PA curves higher specificity. Most parameters had a high predictive value of negative result (NPV > 90 %) but low predictive value of positive result (PPV < 50 %). Best discrimination of low EM was obtained with a combination of both WK and PA parameters (diagnostic accuracy of 90 %). Using PA curves in kidneys with late PT-WK made possible to increase the diagnostic accuracy from 70 - 80 % (with WK parameters only) to 95 %. Our results demonstrate that PA curves carry additional clinical information and may help to predict and Interpret a diuretic response especially in kidneys with late peak of the WK curves. (author)

Feeding broiler breeder males. 4. Deficient feed allocation reduces fertility and broiler progeny body weight.

Science.gov (United States)

Romero-Sanchez, H; Plumstead, P W; Leksrisompong, N; Brannan, K E; Brake, J

2008-04-01

Two experiments were conducted to evaluate the effects of male broiler breeder feed intake on broiler progeny performance. In experiment 1, a low cumulative nutrition program supplied 29,580 kcal of ME and 1,470 g of CP, whereas a high cumulative nutrition program supplied 33,500 kcal of ME and 1,730 g of CP to photostimulation at 21 wk of age. Two diets (HiDiet and LoDiet) were formulated, and a single feeding program was used to achieve the selected nutrient intakes. The HiDiet group of males in experiment 1 achieved greater BW and exhibited lower fertility when fed as the LoDiet males from the onset of egg production. The HiDiet breeder males subsequently produced male broilers from eggs laid at 29 wk of age that exhibited lower BW at 42 d. This was due to the heaviest 50% of the breeder males in this treatment not gaining BW consistently due to less-than-adequate ME intake relative to their greater BW requirements. Two feeding programs during the production period (constant or increasing) were compared in experiment 2. Broilers were hatched from eggs laid at 32 and 48 wk of age to evaluate the vertical effect of male treatments on progeny performance. No difference in fertility or broiler performance was found at 32 wk. However, the constant feeding program produced lower fertility from 36 to 55 wk of age, and this resulted in a lower male and female broiler progeny BW at 42 d of age from eggs collected at 48 wk of age. Adequate breeder male feed allocation during the production period improved fertility and favorably affected broiler progeny performance in both experiments. However, broiler progeny effects were observed only when there were differences in fertility, which suggests that the males with the greatest genetic potential were not mating at these times.

Exercise restores decreased physical activity levels and increases markers of autophagy and oxidative capacity in myostatin/activin-blocked mdx mice.

Science.gov (United States)

Hulmi, Juha J; Oliveira, Bernardo M; Silvennoinen, Mika; Hoogaars, Willem M H; Pasternack, Arja; Kainulainen, Heikki; Ritvos, Olli

2013-07-15

The importance of adequate levels of muscle size and function and physical activity is widely recognized. Myostatin/activin blocking increases skeletal muscle mass but may decrease muscle oxidative capacity and can thus be hypothesized to affect voluntary physical activity. Soluble activin receptor IIB (sActRIIB-Fc) was produced to block myostatin/activins. Modestly dystrophic mdx mice were injected with sActRIIB-Fc or PBS with or without voluntary wheel running exercise for 7 wk. Healthy mice served as controls. Running for 7 wk attenuated the sActRIIB-Fc-induced increase in body mass by decreasing fat mass. Running also enhanced/restored the markers of muscle oxidative capacity and autophagy in mdx mice to or above the levels of healthy mice. Voluntary running activity was decreased by sActRIIB-Fc during the first 3-4 wk correlating with increased body mass. Home cage physical activity of mice, quantified from the force plate signal, was decreased by sActRIIB-Fc the whole 7-wk treatment in sedentary mice. To understand what happens during the first weeks after sActRIIB-Fc administration, when mice are less active, healthy mice were injected with sActRIIB-Fc or PBS for 2 wk. During the sActRIIB-Fc-induced rapid 2-wk muscle growth period, oxidative capacity and autophagy were reduced, which may possibly explain the decreased running activity. These results show that increased muscle size and decreased markers of oxidative capacity and autophagy during the first weeks of myostatin/activin blocking are associated with decreased voluntary activity levels. Voluntary exercise in dystrophic mice enhances the markers of oxidative capacity and autophagy to or above the levels of healthy mice.

Kinematic vorticity number – a tool for estimating vortex sizes and circulations

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Lisa Schielicke

2016-02-01

Full Text Available The influence of extratropical vortices on a global scale is mainly characterised by their size and by the magnitude of their circulation. However, the determination of these properties is still a great challenge since a vortex has no clear delimitations but is part of the flow field itself. In this work, we introduce a kinematic vortex size determination method based on the kinematic vorticity number Wk to atmospheric flows. Wk relates the local rate-of-rotation to the local rate-of-deformation at every point in the field and a vortex core is identified as a simply connected region where the rotation prevails over the deformation. Additionally, considering the sign of vorticity in the extended Wk-method allows to identify highs and lows in different vertical layers of the atmosphere and to study vertical as well as horizontal vortex interactions. We will test the Wk-method in different idealised -D (superposition of two lows/low and jet and real -D flow situations (winter storm affecting Europe and compare the results with traditional methods based on the pressure and the vorticity fields. In comparison to these traditional methods, the Wk-method is able to extract vortex core sizes even in shear-dominated regions that occur frequently in the upper troposphere. Furthermore, statistics of the size and circulation distributions of cyclones will be given. Since the Wk-method identifies vortex cores, the identified radii are subsynoptic with a broad peak around 300–500 km at the 1000 hPa level. However, the total circulating area is not only restricted to the core. In general, circulations are in the order of 107 m2/s with only a few cyclones in the order of 108 m2/s.

Association between leisure time physical activity and depressive symptoms in men.

Science.gov (United States)

Sieverdes, John C; Ray, Billy M; Sui, Xuemei; Lee, Duck-Chul; Hand, Gregory A; Baruth, Meghan; Blair, Steven N

2012-02-01

We examined the association between depressive symptoms and physical activity (PA) in a sample of men from the Aerobics Center Longitudinal Study. Secondary analysis included stratification by age and body mass index (BMI). Our cross-sectional analysis included 9580 men, age 20-87 yr, who completed the 10-item Center for Epidemiological Studies Depression Scale during 1996-2006. A score of 10 or higher defined depressive symptoms. Four PA categories based on the 2008 PA guidelines were created from a self-report leisure time PA questionnaire: inactive (0 MET·min·wk(-1)), low (1-499 MET·min·wk(-1)), medium (500-999 MET·min·wk(-1)), and high (≥1000 MET·min·wk(-1)). There were 727 men with depressive symptoms. Cross-sectional analyses showed a significant inverse relationship between PA categories and depressive symptoms (P for trend leisure time activities (odds ratios = 0.36-0.58). Compared with the inactive group, the light, medium, and high PA categories were 24%, 51%, and 51% less likely to exhibit depressive symptoms, respectively. The inverse relationship was maintained for age and BMI groups except for those 60 yr or older, who exhibited fewer depressive symptoms than other ages. Men with a BMI of 30 kg·m(-2) or higher lowered their odds of depressive symptoms for all PA categories, whereas those with a BMI less than 30 kg·m(-2) needed at least 500 MET·min·wk(-1) to show a similar association. Overall, our analyses found an inverse association between PA and depressive symptoms. Most of this benefit was seen in the medium PA category, which seemed to plateau around 500 MET·min·wk(-1). This indicates that men meeting the 2008 PA Guidelines may not only experience physical health benefits but also reduce the likelihood of depressive symptoms.

The Twins Study: NASA's First Foray into 21st Century Omics Research

Science.gov (United States)

Kundrot, C. E.; Shelhamer, M.; Scott, G. B. I.

2015-01-01

The full array of 21st century omics-based research methods should be intelligently employed to reduce the health and performance risks that astronauts will be exposed to during exploration missions beyond low Earth Orbit. In March of 2015, US Astronaut Scott Kelly will launch to the International Space Station for a one year mission while his twin brother, Mark Kelly, a retired US Astronaut, remains on the ground. This situation presents an extremely rare flight opportunity to perform an integrated omics-based demonstration pilot study involving identical twin astronauts. A group of 10 principal investigators has been competitively selected, funded, and teamed together to form the Twins Study. A very broad range of biological function are being examined including the genome, epigenome, transcriptome, proteome, metabolome, gut microbiome, immunological response to vaccinations, indicators of atherosclerosis, physiological fluid shifts, and cognition. The plans for the Twins Study and an overview of initial results will be described as well as the technological and ethical issues raised for such spaceflight studies. An anticipated outcome of the Twins Study is that it will place NASA on a trajectory of using omics-based information to develop precision countermeasures for individual astronauts.

High intake of regular-fat cheese compared with reduced-fat cheese does not affect LDL cholesterol or risk markers of the metabolic syndrome

DEFF Research Database (Denmark)

Raziani, Farinaz; Tholstrup, Tine; Kristensen, Marlene Dahlwad

2016-01-01

was to compare the effects of regular-fat cheese with an equal amount of reduced-fat cheese and an isocaloric amount of carbohydrate-rich foods on LDL cholesterol and risk factors for the metabolic syndrome (MetS). DESIGN: The study was a 12-wk randomized parallel intervention preceded by a 2-wk run-in period...

Usefulness of cardiac 125I-metaiodobenzylguanidine uptake for evaluation of cardiac sympathetic nerve abnormalities in diabetic rats

International Nuclear Information System (INIS)

Abe, Nanami; Kashiwagi, Atsunori; Shigeta, Yukio

1992-01-01

We investigated cardiac sympathetic nerve abnormalities in streptozocin-induced diabetic rats using 125 I-metaiodobenzylguanidine (MIBG). The radioactivity ratio of cardiac tissue to 1 ml blood (H/B) was used as an index of cardiac MIBG uptake. Cardiac 125 I-MIBG uptake (H/B) in 4-, 8- and 20-wk diabetic rats was 48% lower than that in control rats. Similar results were obtained even when the data were corrected for g wet tissue weight. Although there was no improvement in H/B following 2-wk insulin treatment, the H/B ratio increased significantly, to 85% of control levels, following 4 wk insulin treatment indicating the reversibility of impaired MIBG uptake in diabetic rats. In vivo reserpine treatment resulted in a 50% reduction in the H/B value in control rats. However, the treatment did not significantly suppress uptake in diabetic rats. Cardiac norepinephrine content in both * 4- and ** 8-wk diabetic rats was significantly ( * p ** p 125 I-MIBG in diabetic rats is significantly impaired due to cardiac sympathetic nerve abnormalities. These abnormalities are reversible, however, dependent on the diabetic state. (author)

Effects of 1 versus 2 games a week on physical and subjective scores of subelite soccer players.

Science.gov (United States)

Rollo, Ian; Impellizzeri, Franco M; Zago, Matteo; Iaia, F Marcello

2014-05-01

The physical-performance profiles of subelite male footballers were monitored during 6 wk of a competitive season. The same squad of players played either 1 (1G, n = 15) or 2 (2G, n = 15) competitive matches per week. On weeks 0, 3, and 6, 48 h postmatch, players completed countermovement jump (CMJ), 10- and 20-m sprints, the Yo-Yo Intermittent Recovery Test (YYIRT), and the Recovery-Stress Questionnaire. Both groups undertook 2 weekly training sessions. The 2G showed after 6 wk lower YYIRT (-11% to 3%, 90% CI -15.8% to -6.8%; P m (4.4%, 1.8-6.9%; P = .007) and 20-m sprints values (4.7%, 2.9% to 6.4%; P < .001). No differences were found at 3 wk (.06 < P < .99). No changes over time (.169 < P < .611) and no differences time × group interactions (.370 < P < .550) were found for stress, recovery, and the Stress Recovery Index. In conclusion players' ability to sprint, jump, and perform repeated intense exercise was impaired when playing 2 competitive matches a week over 6 wk.

Gestational Age and Manifest Cardiovascular Risk Factors in ...

African Journals Online (AJOL)

Thus manifestation of known CAD risk factors was evaluated in 75 human females, randomly assigned to 3 groups each of 25 subjects of different GA. Group1 served as Control (NO PREG), Groups 2 and 3 were PREG at GA of less than 20weeks (PREG<20wk) and of 20weeks or more (PREG ≥ 20wk) respectively.

Predicted high-performing piglets exhibit more and larger skeletal muscle fibers

NARCIS (Netherlands)

Paredes Escobar, S.P.; Kalbe, C.; Jansman, A.J.M.; Verstegen, M.W.A.; Hees, van H.M.J.; Lösel, D.; Gerrits, W.J.J.; Rehfeldt, C.

2013-01-01

Postnatal (muscle) growth potential in pigs depends on the total number and hypertrophy of myofibers in skeletal muscle tissue. In a previous study an algorithm was developed to predict piglet BW at the end of the nursery period (10 wk of age) on the basis of BW at birth, at weaning, and at 6 wk of

Synchronization of the seminiferous epithelium after vitamin A replacement in vitamin A-deficient mice

NARCIS (Netherlands)

van Pelt, A. M.; de rooij, D. G.

1990-01-01

The effect of vitamin A deficiency and vitamin A replacement on spermatogenesis was studied in mice. Breeding pairs of Cpb-N mice were given a vitamin A-deficient diet for at least 4 wk. The born male mice received the same diet and developed signs of vitamin A deficiency at the age of 14-16 wk. At

The effects of a ration change from a total mixed ration to pasture on rumen fermentation, volatile fatty acid absorption characteristics, and morphology of dairy cows

NARCIS (Netherlands)

Schären, M.; Seyfang, G.M.; Steingass, H.; Dieho, K.; Dijkstra, J.; Hüther, L.; Frahm, J.; Beineke, A.; Soosten, von D.; Meyer, U.; Breves, G.; Dänicke, S.

2016-01-01

To investigate the effect of the change from a concentrate and silage-based ration (total mixed ration, TMR) to a pasture-based ration, a 10-wk trial (wk 1-10) was performed, including 10 rumen- and duodenum-fistulated German Holstein dairy cows (182 ± 24 d in milk, 23.5 ± 3.5 kg of milk/d; mean

Experimental study of hypersecretion of mucus in the bronchial tree

Energy Technology Data Exchange (ETDEWEB)

Reid, L

1963-01-01

Rats were exposed to 40 or 300 to 400 ppm SO/sub 2/ for 5 hr/day, 5 day/wk. Three-mo exposure to 40 ppm yielded no great change. At 300 to 400 ppm, considerable mucus was observed in many animals by the 4th wk. There was accompanying hypertrophy and hyperplasia of mucus-secreting goblet cells.

A Novel WRKY transcription factor is required for induction of PR-1a gene expression by salicylic acid and bacterial elicitors

NARCIS (Netherlands)

van Verk, Marcel C|info:eu-repo/dai/nl/327618671; Pappaioannou, Dimitri; Neeleman, Lyda; Bol, John F; Linthorst, Huub J M

PR-1a is a salicylic acid-inducible defense gene of tobacco (Nicotiana tabacum). One-hybrid screens identified a novel tobacco WRKY transcription factor (NtWRKY12) with specific binding sites in the PR-1a promoter at positions -564 (box WK(1)) and -859 (box WK(2)). NtWRKY12 belongs to the class of

The influence of postnatal nutrition on reproductive tract and endometrial gland development in dairy calves.

Science.gov (United States)

Wilson, Meghan L; McCoski, Sarah R; Geiger, Adam J; Akers, R Michael; Johnson, Sally E; Ealy, Alan D

2017-04-01

Uterine gland development occurs after birth in cattle and other mammals. The timeline of gland development has been described in various species, but little is known about how postnatal diet influences uterine gland development. This is especially concerning in dairy heifers, where a variety of milk replacer and whole milk nutrition options exist. Little work also exists in cattle to describe how early exposure to steroids influences reproductive tract and uterine gland development. The objective of this work was to determine the effects of early postnatal plane of nutrition and estrogen supplementation on uterine gland development in calves. In both studies, Holstein heifer calves were assigned to restricted milk replacer (R-MR) or enhanced milk replacer (EH-MR) diets. In study 1, calves (R-MR, n = 6; EH-MR, n = 5) were euthanized at 8 wk. In study 2, calves were weaned at 8 wk and administered estradiol (R-MR, n = 6; EH-MR, n = 6) or placebo (R-MR, n = 6; EH-MR, n = 5) for an additional 14 d before euthanasia. Average daily gain and final body weight was greater in both studies in heifers fed the enhanced diet. At 8 wk, EH-MR calves had a greater number of glands and a smaller average gland size, but total gland area was not different from the R-MR group. At 10 wk, uterine gland number and size were not affected by diet or estrogen. Expression profiles of several paracrine mediators of gland development were examined. Increases in transcript abundance for IGF1 and IGFBP3 and a decrease in abundance of WNT7A were detected in calves fed the enhanced diet at 8 wk of age. Plane of nutrition did not affect transcript profiles at 10 wk of age, but estradiol supplementation decreased MET and WNT7A transcript abundance. To conclude, heifer calves on a restricted diet exhibited a uterine morphology and transcript profile suggestive of delayed uterine gland development. These changes appear to be corrected by wk 10 of life. Also, this work provides evidence supporting the

Experimental infection of nontarget species of rodents and birds with Brucella abortus strain RB51 vaccine

Science.gov (United States)

Januszewski, M.C.; Olsen, S.C.; McLean, R.G.; Clark, L.; Rhyan, Jack C.

2001-01-01

The Brucella abortus vaccine strain RB51 (SRB51) is being considered for use in the management of bnucellosis in wild bison (Bison bison) and elk (Cervus elaphus) populations in the Greater Yellowstone Area (USA). Evaluation of the vaccines safety in non-target species was considered necessary prior to field use. Between June 1998 and December 1999, ground squirrels (Spermophilus richardsonii, n = 21), deer mice (Peromyscus maniculatus, n = 14), prairie voles (Microtus ochrogaster, n = 21), and ravens (Corvus corax, n = 13) were orally inoculated with SRB51 or physiologic saline. Oral and rectal swabs and blood samples were collected for bacteriologic evaluation. Rodents were necropsied at 8 to 10 wk and 12 to 21 wk post inoculation (PI), and ravens at 7 and 11 wk PI. Spleen, liver and reproductive tissues were collected for bacteriologic and histopathologic evaluation. No differences in clinical signs, appetite, weight loss or gain, or activity were observed between saline- and SRB51-inoculated animals in all four species. Oral and rectal swabs from all species were negative throughout the study. In tissues obtained from SRB51-inoculated animals, the organism was isolated from six of seven (86%) ground squirrels, one of six (17%) deer mice, none of seven voles, and one of five (20%) ravens necropsied at 8, 8, 10, and 7 wk PI, respectively. Tissues from four of seven (57%) SRB51-inoculated ground squirrels were culture positive for the organism 12 wk PI; SRB51 was not recovered from deer mice, voles. or ravens necropsied 12, 21, or 11 wk, respectively, PI. SRB51 was not recovered from saline-inoculated ground squirrels, deer mice, or voles at any time but was recovered from one saline-inoculated raven at necropsy, 7 wk PI, likely attributable to contact with SRB51-inoculated ravens in an adjacent aviary room. Spleen was time primary tissue site of colonization in ground squirrels, followed by the liver and reproductive organs. The results indicate oral exposure to

Evaluation of conjugated linoleic acid and dietary antibiotics as growth promotants in weanling pigs.

Science.gov (United States)

Weber, T E; Schinckel, A P; Houseknecht, K L; Richert, B T

2001-10-01

An experiment was conducted to determine the efficacy of dietary conjugated linoleic acid (CLA) as a growth promotant in weanling swine. Weanling pigs (n = 192; 7.6 kg and 29 d of age) were randomly assigned to four treatments that were arranged as a 2 x 2 factorial. Concentrations of dietary CLA (0 or 0.6%) and antibiotics (+/-) constituted the main effect variables. Dietary CLA treatments consisted of a 1% addition of an oil containing 60% CLA isomers or 1% soybean oil, and dietary antibiotic treatments were antibiotics or no antibiotics. The experimental diets were fed for 9 wk in four phases (1, wk 1; 2, wk 2 and 3; 3, wk 4 through 6; and 4, wk 7 through 9), after which all pigs were fed identical medicated diets for the duration of the finishing phase. Live weights were recorded at wk 17 postweaning and at marketing to determine any residual effects of dietary treatments on finisher ADG and days to market. Medicated diets fed during phases 1 and 2 contained 55 mg carbadox/kg; during phase 3 contained 299 mg tilmicosin/kg; and during phase 4 contained 110 mg tylosin and 110 mg sulfamethazine/kg. Pigs fed medicated diets had higher overall ADG than pigs fed unmedicated diets for wk 0 through 9 (P pigs fed medicated diets than for pigs fed unmedicated diets during phase 1 (P residual effects of nursery CLA or antibiotics on finisher ADG and days to market. Blood samples collected from a subset of pigs (n = 72) at the completion of phases 2, 3, and 4 were assayed for serum IGF-I and antibody concentrations to porcine reproductive and respiratory syndrome virus (PRRSV) and Mycoplasma hyopneumoniae. There was a tendency for pigs fed medicated diets to have greater IGF-I concentrations than pigs fed unmedicated diets at the completion of phase 4 (P Pigs fed CLA had greater antibody titers (P pigs fed diets without CLA. These results indicate that feeding 0.6% dietary CLA did not enhance growth performance in weanling swine and that the use of dietary antibiotics can

Effects of preincubation heating of broiler hatching eggs during storage, flock age, and length of storage period on hatchability.

Science.gov (United States)

Gucbilmez, M; Ozlü, S; Shiranjang, R; Elibol, O; Brake, J

2013-12-01

The effects of heating of eggs during storage, broiler breeder age, and length of egg storage on hatchability of fertile eggs were examined in this study. Eggs were collected from Ross 344 male × Ross 308 broiler breeders on paper flats, held overnight (1 d) at 18°C and 75% RH, and then transferred to plastic trays. In experiment 1, eggs were obtained at 28, 38, and 53 wk of flock age. During a further 10 d of storage, eggs either remained in the storage room (control) or were subjected to a heat treatment regimen of 26°C for 2 h, 37.8°C for 3 h, and 26°C for 2 h in a setter at d 5 of storage. In experiment 2, eggs from a flock at 28 wk of age were heated for 1 d of a 6-d storage period. Eggs from a 29-wk-old flock were either heated at d 1 or 5 of an 11-d storage period in experiment 3. In experiment 4, 27-wk-old flock eggs were heated twice at d 1 and 5 of an 11-d storage period. Control eggs stored for 6 or 11 d were coincubated as appropriate in each experiment. Heating eggs at d 5 of an 11-d storage period increased hatchability in experiment 1. Although no benefit of heating 28-wk-old flock eggs during 6 d of storage in experiment 2 was observed, heating eggs from a 29-wk-old flock at d 1 or 5 of an 11-d storage period increased hatchability in experiment 3. Further, heating eggs from a 27-wk-old flock twice during 11 d of storage increased hatchability in experiment 4. These effects were probably due to the fact that eggs from younger flocks had been reported to have many embryos at a stage of development where the hypoblast had not yet fully developed (less than EG-K12 to EG-K13), such that heating during extended storage advanced these embryos to a more resistant stage.

Assessment of frequent litter amendment application on ammonia emission from broilers operations.

Science.gov (United States)

Li, Hong; Lin, Chongyang; Collier, Stephen; Brown, William; White-Hansen, Susan

2013-04-01

Litter amendments have been used to control the ammonia (NH3) emission from the broiler litter during the brooding period. One of the commercially available litter amendments, sodium bisulfate, was frequently applied on the litter with two different rates on weekly basis in a laboratory setup and with a single rate on biweekly basis under field conditions. Repeated application ofsodium bisulfate led to significant reduction in NH3 emissions from broilers. The magnitude of NH3 emission reduction increases with the application rate of sodium bisulfate. The reduction rates of cumulative emissions with 366 g/wk-m2 (75 lb/wk-1000 ft) rate (from 14% to 64.5%) were higher than the reduction rate of 183 g/wk-m2 (37.5 lb/wk-1000 ft2) rate (from 0% to 55%) from 28 to 61 days of age. The cumulative NH3 emission was reduced by 51.7% with 244 g/2 wk-m2 (50 lb/2 wk-1000 ft2) rate over a three-flockperiod (8-wk average grow-out per flock) under field production conditions. Sodium bisulfate application showed no significant difference on body weight and feed conversion efficiency. However, footpad quality was significantly improved by sodium bisulfate application. Litter pH and ammonia nitrogen level of the litter were decreased by sodium bisulfate application with both rates. Organic and total nitrogen contents in the litter were higher, whereas less nitrogen was emitted as NH3. The laboratory-scale findings of emission reduction by the additives should be considered to be preliminary if the additives are to be applied under commercial production settings. This work demonstrated that frequent litter amendment application can be used to reduce NH3 emissions from broiler houses, with no adverse effect on the animal production performances. The NH3 reduction rates could vary with different application frequencies and rates. Using litter amendment during broiler grow-out to lower NH3 emissions should be applicable to boiler production systems. The results of this study also

40 aastat vanglat arvutivõhikluse eest / Elver Loho

Index Scriptorium Estoniae

Loho, Elver

2007-01-01

USA-s Connecticuti osariigis Norwichi linna Kelly Põhikoolis juhtus 2004. aastal sündmus, mille tagajärjel mõisteti õpetaja Julie Amero süüdi maksimaalse karistusajaga 40 aastat. Õpetaja oli väljunud korraks klassist ja võimaldanud lastel klikata tema arviti lingile, mis käivitas pahatahtliku programmi pornograafiliste piltidega, mida võhiklik õpetaja ei osanud tagasi tulles kohe sulgeda