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Sample records for keerberg hiie ivanova

  1. Mida huvitavat koolivaheajal tegite? / Hiie Asser, Aires Põder, Kirke Algma ... [jt.

    Index Scriptorium Estoniae

    2009-01-01

    Küsimusele vastavad Annelinna gümnaasiumi direktor Hiie Asser, Sürgavere kooli direktor Aires Põder, Tallinna 32. keskkooli 10. klassi õpilane Kirke Algma, Unipiha algkooli õpetaja Lembit Jakobson ja Kirivere põhikooli direktor Mare Kolk

  2. Lapsed väärivad head teatrit, mitte haltuurapalagani / Toomas Tross, Hiie Fluss ; intervjueerinud Meeli Parijõgi

    Index Scriptorium Estoniae

    Tross, Toomas, 1966-

    2014-01-01

    Tallinnas Vaba Lava teatrimajas toimub 28.-30. oktoobrini festival „Teater noorele vaatajale”. ASSITEJ (Association Internationale du Theatre pour l'Enfance et la Jeunesse) Eesti keskuse juhatuse esimees Toomas Tross ja juhatuse liige Hiie Fluss arutlevad lastele suunatud teatri kvaliteedi üle

  3. Triumf gruzinskogo kino / Irina Ivanova

    Index Scriptorium Estoniae

    Ivanova, Irina

    2005-01-01

    Anapas lõppes SRÜ ja Baltimaade XIV avatud filmifestival "Kinoshokk 2005". Žürii andis parima näitlejanna preemia Maarja Jakobsonile tema rolli eest P. Urbla filmis "Stiilipidu". Parima filmi auhinna sai grusiin Levan Tutberidze "Jalutuskäik Mägi-Karabahhis" ja parima režii auhinna samuti grusiin Levan Zakareishvili filmi eest "Thbilisi-Thbilisi"

  4. Eto otshen strashno! / Irina Ivanova

    Index Scriptorium Estoniae

    Ivanova, Irina

    2005-01-01

    Walden Media tootis koos Walt Disney Pictures'iga ekraniseeringu C.S. Lewise 1950.a. ilmunud romaanist "Narnia lood : Lõvi, nõid ja riidekapp" (Chronicles of Narnia : The Lion, the Witch and the Wardrobe")

  5. Haridustehnoloogiaalane mess / Ija Ivanova, Kristiina Klaas

    Index Scriptorium Estoniae

    Ivanova, Ija

    2007-01-01

    Muljeid Londonis toimunud haridustehnoloogiaalaselt messilt BETT, mis toob kokku ülemaailmse õpetamise ja õppimise kogukonna liikmed, kes saavad nelja päeva jooksul osa rikkalikust uue tehnoloogia valikust, innovaatilistest ideedest ja ajakohastest nõuannetest

  6. Kas maksurevolutsioon tuleb ka Eestis? / Hiie Marrandi

    Index Scriptorium Estoniae

    Marrandi, Hiie

    2016-01-01

    Majanduskoostöö ja Arengu Organisatsiooni (OECD) välja töötatud maksubaasi kahanemise ja kasumi ümberpaigutamise vastasest BEPS nimelisest meetmete paketist ning Euroopa Liidu uuest maksude vältimise vastasest direktiivist (ATAD) ning nende mõjust Eesti, Läti ja Leedu maksusüsteemidele

  7. Sobstvennost nuzhna ne avtomobilju, a jego vladeltsu / Gortenzija Ivanova

    Index Scriptorium Estoniae

    Ivanova, Gortenzija

    2007-01-01

    Garaažiühistute ümberregistreerimisest. Lisatud kommentaar: Järv. Maris. Iz garazhei mozhno sozdat kvartirnoje tovarishtshestvo. - Vastukaja artiklile: Suhnjova, Marina. Nuzhna li avtomobilju kvartirnaja sobstvennost // Delovõje Vedomosti, 13. juuni 2007, lk. 15

  8. Arusaamatused eluasemelaenu intressi tulumaksusoodustusega / Hiie Õunpuu

    Index Scriptorium Estoniae

    Õunpuu, Hiie

    2005-01-01

    Eluasemelaenu intresside tulust mahaarvamise kohta. Lisatud: Kask, Evelyn. Maksusoodustuse mõte on toetada eluaseme soetamist, lk. 34 ; Lehis, Lasse. MTA teeb liiga suuri üldistusi, lk. 34. Vt. ka Maksumaksja 2005, nr 2, lk 21-24. - Vt. ka: http://www.maksumaksjad.ee/modules/smartsection/item.php?itemid=78 ; http://www.maksumaksjad.ee/modules/smartsection/item.php?itemid=79.

  9. Parkimistasu ja viivistasu - sigakoer Eesti maksumaastikul / Hiie Marrandi, Martin Huberg

    Index Scriptorium Estoniae

    Marrandi, Hiie

    2008-01-01

    Parkimistasu aegumisest, viivistasu olemusest ja maksustamisest. Lisatud: Maksumaksja soovitab veel sõiduautode kohta lugeda ; EML selgitustaotlus Maksu- ja Tolliametile ; Kindsigo, Aule. MTA vastus selgitustaotlusele ; Huvitav kokkusattumus ; Lehis, Lasse. Mulle meeldib see! - Vt.: http://www.maksumaksjad.ee/modules/smartsection/item.php?itemid=575.

  10. Rahvusvahelise lugemisühingu konverents Edinburghis / Hiie Asser

    Index Scriptorium Estoniae

    Asser, Hiie

    2003-01-01

    29.07.-1.08.2002 toimus Šotimaa pealinnas Edinburghis lugemisühingu maailmakonverents, peakorraldajaks Ühendatud Kuningriigi Lugemisühing (UKRA). Konverentsi üldteemaks oli "International Literacy Links" ("Rahvusvaheline kirjaoskus ühendab")

  11. Maksutõusu maavõistlus: Hispaania vs Eesti / Hiie Marrandi

    Index Scriptorium Estoniae

    Marrandi, Hiie

    2009-01-01

    Hispaanias kaotati 2008. aasta lõpus tagasiulatuvalt senikehtinud progresseeruv varandusemaks. Eesti maksupoliitikast. Vastukaja artiklile: Colldefors, Ana. Abolition of Spanish net wealth tax and its effects // European Taxation (2009) no. 4, p. 230-231

  12. 11.11.11 - päev, mis jääb kauaks meelde / Hiie Marrandi

    Index Scriptorium Estoniae

    Marrandi, Hiie

    2011-01-01

    Ülevaade maksukonverentsist, mille põhiteemadeks olid ariühingute tulumaksu ühtsest konsolideeritud maksubaas (common consolidated corporate tax base - CCCTB) ja finantsteenuste maks (financial transaction tax - FTT)

  13. Loojatega/loojate loomingust : Tartu Forseliuse gümnaasiumi 31. kirjanduspäeval / Hiie Saumaa

    Index Scriptorium Estoniae

    Saumaa, Hiie

    2002-01-01

    Tartu Forseliuse Gümnaasiumi 31. kirjanduspäev toimus 28. märtsil 2002.a. kandes nime "Üle kõige on maailmal vaja ...". Esinesid Paul-Eerik Rummo, Kauksi Ülle, Jürgen Rooste, Priit Kruus ja Hedda Maurer

  14. Ülevaade tolli ja käibemaksu teabepäevast / Rait Kaarma, Mariliis Kannukene, Hiie Õunpuu

    Index Scriptorium Estoniae

    Kaarma, Rait

    2004-01-01

    30. märtsil toimunud teabepäevast tolli ja käibemaksu teemal. Ülevaade Heli Tariku, Ruth Paade, Lembar Kivistiku, Martin Hubergi ja Kaia Loobi sõnavõttudest. Lisad: kirjalik tollideklaratsioon (SAD) esitatakse, kui ; tollimaksumäärade, keeldude ja piirangutega saab tutvuda

  15. Hiljutine maksulahend Euroopa Kohtus - ettevõtja kasuks! : Cadbury Schweppes vs. Ühendkuningriigi maksuhaldur, C-196/04 / Hiie Marrandi

    Index Scriptorium Estoniae

    Marrandi, Hiie

    2006-01-01

    Euroopa Kohtu eelotsusetaotluse alusel tehtud lahendist (12. 09. 2006 C-196/04) Cadbury Schweppes´i ja Suurbritannia maksuhalduri vaidluse kohta, mis puudutas madala maksumääraga territooriumil asuva tütarühingu tulu omistamist Suurbritannia emaühingule

  16. 30. XI avati Y-galeriis...

    Index Scriptorium Estoniae

    2005-01-01

    Projekt "Mina, uurija". Mardus K, Martini ja Liis Keerberg esitavad fotodokumente, videosid jms, mille abil tõstatavad ning püüavad lahendada uurijatöös ettetulevaid küsimusi. P- ja T-saalis saab vaadata Liina Veedleri installatsioone

  17. High-Intensity Intermittent Exercise and Fat Loss

    Directory of Open Access Journals (Sweden)

    Stephen H. Boutcher

    2011-01-01

    Full Text Available The effect of regular aerobic exercise on body fat is negligible; however, other forms of exercise may have a greater impact on body composition. For example, emerging research examining high-intensity intermittent exercise (HIIE indicates that it may be more effective at reducing subcutaneous and abdominal body fat than other types of exercise. The mechanisms underlying the fat reduction induced by HIIE, however, are undetermined. Regular HIIE has been shown to significantly increase both aerobic and anaerobic fitness. HIIE also significantly lowers insulin resistance and results in a number of skeletal muscle adaptations that result in enhanced skeletal muscle fat oxidation and improved glucose tolerance. This review summarizes the results of HIIE studies on fat loss, fitness, insulin resistance, and skeletal muscle. Possible mechanisms underlying HIIE-induced fat loss and implications for the use of HIIE in the treatment and prevention of obesity are also discussed.

  18. High-intensity interval exercise and glycemic control in adolescents with type one diabetes mellitus: a case study.

    Science.gov (United States)

    Cockcroft, Emma J; Moudiotis, Christopher; Kitchen, Julie; Bond, Bert; Williams, Craig A; Barker, Alan R

    2017-07-01

    Current physical activity guidelines for youth with type 1 diabetes (T1D) are poorly supported by empirical evidence and the optimal dose of physical activity to improve glycemic control is unknown. This case report documents the effect of acute high-intensity interval exercise (HIIE) and moderate-intensity exercise (MIE) on 24-h glycemic control in three adolescents with T1D using continuous glucose monitoring. Results highlight varied individual response to exercise across the participants. In two participants both MIE and HIIE resulted in a drop in blood glucose during exercise (-38 to -42% for MIE and -21-46% in HIIE) and in one participant both MIE and HIIE resulted in increased blood glucose (+19% and + 36%, respectively). Over the 24-h period average blood glucose was lower for all participants in the HIIE condition, and for two for the MIE condition, compared to no exercise. All three participants reported HIIE to be more enjoyable than MIE These data show both HIIE and MIE have the potential to improve short-term glycemic control in youth with T1D but HIIE was more enjoyable. Future work with a larger sample size is required to explore the potential for HIIE to improve health markers in youth with T1D. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

  19. High-intensity interval exercise attenuates but does not eliminate endothelial dysfunction after a fast food meal.

    Science.gov (United States)

    Tucker, Wesley J; Sawyer, Brandon J; Jarrett, Catherine L; Bhammar, Dharini M; Ryder, Justin R; Angadi, Siddhartha S; Gaesser, Glenn A

    2018-02-01

    We investigated whether two different bouts of high-intensity interval exercise (HIIE) could attenuate postprandial endothelial dysfunction. Thirteen young (27 ± 1 yr), nonexercise-trained men underwent three randomized conditions: 1) four 4-min intervals at 85-95% of maximum heart rate separated by 3 min of active recovery (HIIE 4 × 4), 2) 16 1-min intervals at 85-95% of maximum heart rate separated by 1 min of active recovery (HIIE 16 × 1), and 3) sedentary control. HIIE was performed in the afternoon, ~18 h before the morning fast food meal (1,250 kcal, 63g of fat). Brachial artery flow-mediated dilation (FMD) was performed before HIIE ( baseline 1), during fasting before meal ingestion ( baseline 2), and 30 min, 2 h, and 4 h postprandial. Capillary glucose and triglycerides were assessed at fasting, 30 min, 1 h, 2 h, and 4 h (triglycerides only). Both HIIE protocols increased fasting FMD compared with control (HIIE 4 × 4: 6.1 ± 0.4%, HIIE 16 × 1: 6.3 ± 0.5%, and control: 5.1 ± 0.4%, P fast food meal can attenuate but not entirely eliminate postprandial decreases in FMD. This effect is not dependent on reductions in postprandial lipemia or glycemia. NEW & NOTEWORTHY Two similar high-intensity interval exercise (HIIE) protocols performed ∼18 h before ingestion of a high-energy fast food meal attenuated but did not entirely eliminate postprandial endothelial dysfunction in young men largely by improving fasting endothelial function. Both HIIE protocols produced essentially identical results, suggesting high reproducibility of HIIE effects.

  20. Maintained exercise-enhanced brain executive function related to cerebral lactate metabolism in men

    DEFF Research Database (Denmark)

    Hashimoto, Takeshi; Tsukamoto, Hayato; Takenaka, Saki

    2018-01-01

    . Fourteen healthy, male subjects performed 2 HIIE protocols separated by 60 min of rest. Blood samples were obtained from the right internal jugular venous bulb and from the brachial artery to determine differences across the brain for lactate (a-v difflactate), glucose (diffglucose), oxygen (diffoxygen......High-intensity interval exercise (HIIE) improves cerebral executive function (EF), but the improvement in EF is attenuated after repeated HIIE, perhaps because of lower lactate availability for the brain. This investigation examined whether improved EF after exercise relates to brain lactate uptake......), and brain-derived neurotrophic factor (BDNF; diffBDNF). EF was evaluated by the color-word Stroop task. The first HIIE improved EF for 40 min, whereas the second HIIE improved EF only immediately after exercise. The a-v diffglucose was unchanged, whereas the a-v diffBDNF increased similarly after both HIIEs...

  1. Maailmamainega baleriinid Vanemuises

    Index Scriptorium Estoniae

    1999-01-01

    Vanemuisesse tulevad esinema balletitähed Sankt Peterburgist : V. Medvedev, Bae Joo Yoon, V. Ivanova, N. Bashkirtseva, J. Gludzhidze-Tukanova, E. Habibulina, S. Fecho, F. Miozzi, N. Sheglov, V. Samodurov

  2. the civil society and the regulation of the extractive industry in nigeria

    African Journals Online (AJOL)

    RAYAN_

    in Global Environmental Governance” in Daniel Esty & Maria Ivanova (eds.) ... 7 Bridget Hutter & Joan O'Mahony, “Business Regulation: Reviewing the Regulatory. Potential of ... Institutions in oil Communities” (2008) 55 (1) Africa Today, p. 89.

  3. Mida arvasid väliskülalised ?

    Index Scriptorium Estoniae

    2006-01-01

    Saksa teatrikriitik ja teatripedagoog Manfred Jahnke, Turu Rakenduskõrgkooli Kunstiakadeemia nukukunsti õppetooli juhataja Anna Ivanova-Brashinskaya ja Praha teatri Minor stsenarist ja dramaturg Petra Zamecnikova Eesti laste- ja noorteteatri festivalist "Draamake"

  4. The happy Bulgarian family

    CERN Multimedia

    2000-01-01

    From left to right, last row to first row: Ilka Antcheva, Georgi Antchev, Dimitri Borilkov, Ivana Hristova, Petiu Petev, Peicho Petkov, Borislav Pavlov, Peter Hristov, Mihail Tchijov, Stefan Piperov, Ekaterina Ivanova, Dimitar Kolev, Roumen Tzenov.

  5. The Effect of High-Intensity Intermittent Exercise on Body Composition of Overweight Young Males

    Directory of Open Access Journals (Sweden)

    M. Heydari

    2012-01-01

    Full Text Available To determine the effect of a 12-week high intensity intermittent exercise (HIIE intervention on total body, abdominal, trunk, visceral fat mass, and fat free mass of young overweight males. Participants were randomly assigned to either exercise or control group. The intervention group received HIIE three times per week, 20 min per session, for 12 weeks. Aerobic power improved significantly (P0.05 occurred in levels of insulin, HOMA-IR, and blood lipids. Twelve weeks of HIIE resulted in significant reductions in total, abdominal, trunk, and visceral fat and significant increases in fat free mass and aerobic power.

  6. High intensity interval exercise is an effective alternative to moderate intensity exercise for improving glucose tolerance and insulin sensitivity in adolescent boys.

    Science.gov (United States)

    Cockcroft, Emma J; Williams, Craig A; Tomlinson, Owen W; Vlachopoulos, Dimitris; Jackman, Sarah R; Armstrong, Neil; Barker, Alan R

    2015-11-01

    High-intensity interval exercise (HIIE) may offer a time efficient means to improve health outcomes compared to moderate-intensity exercise (MIE). This study examined the acute effect of HIIE compared to a work-matched bout of MIE on glucose tolerance, insulin sensitivity (IS), resting fat oxidation and exercise enjoyment in adolescent boys. Within-measures design with counterbalanced experimental conditions. Nine boys (14.2 ± 0.4 years) completed three conditions on separate days in a counterbalanced order: (1) HIIE; (2) work matched MIE, both on a cycle ergometer; and (3) rest (CON). An oral glucose tolerance test (OGTT) was performed after exercise or rest and the area under curve (AUC) responses for plasma [glucose] and [insulin] were calculated, and IS estimated (Cederholm index). Energy expenditure and fat oxidation were measured following the OGTT using indirect calorimetry. Exercise enjoyment was assessed using the Physical Activity Enjoyment Scale. The incremental AUC (iAUC) for plasma [glucose] was reduced following both MIE (-23.9%, P = 0.013, effect size [ES] = -0.64) and HIIE (-28.9%, P=0.008, ES = -0.84) compared to CON. The iAUC for plasma [insulin] was lower for HIIE (-24.2%, P = 0.021, ES = -0.71) and MIE (-29.1%, P = 0.012, ES = -0.79) compared to CON. IS increased by 11.2% after HIIE (P = 0.03, ES = 0.76) and 8.4% after MIE (P = 0.10, ES = 0.58). There was a trend for an increase in fat oxidation following HIIE (P = 0.097, ES = 0.70). Both HIIE and MIE were rated as equally enjoyable (P > 0.05, ES effective alternative to MIE for improving glucose tolerance and IS in adolescent boys immediately after exercise. Copyright © 2014 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  7. High intensity interval and moderate continuous cycle training in a physical education programme improves health-related fitness in young females.

    Science.gov (United States)

    Mazurek, K; Zmijewski, P; Krawczyk, K; Czajkowska, A; Kęska, A; Kapuściński, P; Mazurek, T

    2016-06-01

    The aim of the study was to investigate the effects of eight weeks of regular physical education classes supplemented with high intensity interval cycle exercise (HIIE) or continuous cycle exercises of moderate intensity (CME). Forty-eight collegiate females exercising in two regular physical education classes per week were randomly assigned to two programmes (HIIE; n = 24 or CME; n = 24) of additional (one session of 63 minutes per week) physical activity for 8 weeks. Participants performed HIIE comprising 2 series of 6x10 s sprinting with maximal pedalling cadence and active recovery pedalling with intensity 65%-75% HRmax or performed CME corresponding to 65%-75% HRmax. Before and after the 8-week programmes, anthropometric data and aero- and anaerobic capacity were measured. Two-way ANOVA revealed a significant time main effect for VO2max (p body mass not changing significantly (p = 0.59; +0.4% in HIIE and -0.1% in CME). A significant main time effect was found for relative fat mass (FM) and fat-free mass (FFM) (p body composition than physical education classes supplemented with HIIE sessions. In contrast to earlier, smaller trials, similar improvements in aerobic capacity were observed following physical activity with additional HIIE or CME sessions.

  8. Cardiorespiratory Fitness and Body Composition Responses to Different Intensities and Frequencies of Exercise Training in Colorectal Cancer Survivors.

    Science.gov (United States)

    Devin, James L; Jenkins, David G; Sax, Andrew T; Hughes, Gareth I; Aitken, Joanne F; Chambers, Suzanne K; Dunn, Jeffrey C; Bolam, Kate A; Skinner, Tina L

    2018-06-01

    Deteriorations in cardiorespiratory fitness (V˙o 2peak ) and body composition are associated with poor prognosis after colorectal cancer treatment. However, the optimal intensity and frequency of aerobic exercise training to improve these outcomes in colorectal cancer survivors is unknown. This trial compared 8 weeks of moderate-intensity continuous exercise (MICE; 50 minutes; 70% peak heart rate [HR peak ]; 24 sessions), with high-intensity interval exercise (HIIE; 4 × 4 minutes; 85%-95% HR peak ) at an equivalent (HIIE; 24 sessions) and tapered frequency (HIIE-T; 16 sessions) on V˙o 2peak and on lean and fat mass, measured at baseline, 4, 8, and 12 weeks. Increases in V˙o 2peak were significantly greater after both 4 (+3.0 mL·kg -1 ·min -1 , P = .008) and 8 (+2.3 mL·kg -1 ·min -1 , P = .049) weeks of HIIE compared to MICE. After 8 weeks, there was a significantly greater reduction in fat mass after HIIE compared to MICE (-0.7 kg, P = .038). Four weeks after training, the HIIE group maintained elevated V˙o 2peak (+3.3 mL·kg -1 ·min -1 , P = .006) and reduced fat mass (-0.7 kg, P = .045) compared to the MICE group, with V˙o 2peak in the HIIE-T also being superior to the MICE group (+2.8 mL·kg -1 ·min -1 , P = .013). Compared to MICE, HIIE promotes superior improvements and short-term maintenance of V˙o 2peak and fat mass improvements. HIIE training at a reduced frequency also promotes maintainable cardiorespiratory fitness improvements. In addition to promoting accelerated and superior benefits to the current aerobic exercise guidelines, HIIE promotes clinically relevant improvements even with a substantial reduction in exercise training and for a period after withdrawal. Copyright © 2018 Elsevier Inc. All rights reserved.

  9. Acute high-intensity interval exercise induces comparable levels of circulating cell-free DNA and Interleukin-6 in obese and normal-weight individuals.

    Science.gov (United States)

    Ferrandi, Peter J; Fico, Brandon G; Whitehurst, Michael; Zourdos, Michael C; Bao, Fanchen; Dodge, Katelyn M; Rodriguez, Alexandra L; Pena, Gabriel; Huang, Chun-Jung

    2018-06-01

    Obesity is associated with lipid aggregation in adipocytes and macrophage infiltration, leading to increased oxidative stress and inflammation. Increased cell-free DNA (cfDNA) concentrations have been observed in clinical conditions of systemic inflammation. While the beneficial effects of regular physical activity on the release of circulating cfDNA still remain unknown, acute intense exercise has been shown to increase inflammatory cytokines and cfDNA concentrations in normal-weight individuals. Therefore, the primary purpose of this study was to examine the effect of acute high-intensity interval Exercise (HIIE) on plasma cfDNA and interleukin-6 (IL-6) responses in obese and normal-weight subjects. Fourteen male subjects (7 obese and 7 normal-weight) participated in an acute HIIE protocol (30 min, 4x4min @ 80% - 90% of VO 2max ) on a treadmill. Between HIIE intervals, subjects performed 3 min of active recovery at 50-60% VO 2max . Blood samples were collected prior to, immediately following exercise, and one hour into recovery for measurements of plasma cfDNA and IL-6. Our results demonstrated a significant elevation in plasma cfDNA immediately following acute HIIE in both obese and normal-weight subjects. A comparable elevation in the concentration of plasma IL-6 was also found between two groups in response to acute HIIE. Furthermore, the level of plasma cfDNA was not correlated with IL-6 either at baseline or in response to acute HIIE. These findings may support the utilization of HIIE as a time-efficient exercise protocol to understand the obesity-associated cfDNA and inflammatory responses. Published by Elsevier Inc.

  10. Spicules of Litistidic sponges from the upper Eocene Verhivtsevska depression (Miiddle Dniprean

    Directory of Open Access Journals (Sweden)

    Ivanova T.A.

    2014-12-01

    Full Text Available For the first time a taxonomic composition of lithistid sponges which are lived in the Late Eocene basin of Verchovtzev depression Ukrainian Shield is supposed by the spicules morphological analysis. There are sponges of ten geneses and seven families presented in paleocoenosis, but families Theonellidae (geneses Lerouxia, Rhagadinia andPlinthosellidae (genusPlinthosella are dominated. Threenewmorphospeciesof spicules aredescribed: Phyllotriaenapartita T.A.Ivanova morphosp.n., Ph. araneola T.A.Ivanova, morphosp.n., Tetracrepides semiornatus T.A.Ivanova, morphosp.n. Their stratigraphical meaning is determined. These spicules are characteristic for the Obuchovian Suite and would be used as the paleontological criterion of the Obuchovian Suite determination in geological sections of the Middle Dnieper region.

  11. Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin.

    Science.gov (United States)

    Moser, Othmar; Tschakert, Gerhard; Mueller, Alexander; Groeschl, Werner; Pieber, Thomas R; Obermayer-Pietsch, Barbara; Koehler, Gerd; Hofmann, Peter

    2015-01-01

    We investigated blood glucose (BG) and hormone response to aerobic high-intensity interval exercise (HIIE) and moderate continuous exercise (CON) matched for mean load and duration in type 1 diabetes mellitus (T1DM). Seven trained male subjects with T1DM performed a maximal incremental exercise test and HIIE and CON at 3 different mean intensities below (A) and above (B) the first lactate turn point and below the second lactate turn point (C) on a cycle ergometer. Subjects were adjusted to ultra-long-acting insulin Degludec (Tresiba/ Novo Nordisk, Denmark). Before exercise, standardized meals were administered, and short-acting insulin dose was reduced by 25% (A), 50% (B), and 75% (C) dependent on mean exercise intensity. During exercise, BG, adrenaline, noradrenaline, dopamine, cortisol, glucagon, and insulin-like growth factor-1, blood lactate, heart rate, and gas exchange variables were measured. For 24 h after exercise, interstitial glucose was measured by continuous glucose monitoring system. BG decrease during HIIE was significantly smaller for B (p = 0.024) and tended to be smaller for A and C compared to CON. No differences were found for post-exercise interstitial glucose, acute hormone response, and carbohydrate utilization between HIIE and CON for A, B, and C. In HIIE, blood lactate for A (p = 0.006) and B (p = 0.004) and respiratory exchange ratio for A (p = 0.003) and B (p = 0.003) were significantly higher compared to CON but not for C. Hypoglycemia did not occur during or after HIIE and CON when using ultra-long-acting insulin and applying our methodological approach for exercise prescription. HIIE led to a smaller BG decrease compared to CON, although both exercises modes were matched for mean load and duration, even despite markedly higher peak workloads applied in HIIE. Therefore, HIIE and CON could be safely performed in T1DM. ClinicalTrials.gov NCT02075567 http://www.clinicaltrials.gov/ct2/show/NCT02075567.

  12. Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin.

    Directory of Open Access Journals (Sweden)

    Othmar Moser

    Full Text Available We investigated blood glucose (BG and hormone response to aerobic high-intensity interval exercise (HIIE and moderate continuous exercise (CON matched for mean load and duration in type 1 diabetes mellitus (T1DM.Seven trained male subjects with T1DM performed a maximal incremental exercise test and HIIE and CON at 3 different mean intensities below (A and above (B the first lactate turn point and below the second lactate turn point (C on a cycle ergometer. Subjects were adjusted to ultra-long-acting insulin Degludec (Tresiba/ Novo Nordisk, Denmark. Before exercise, standardized meals were administered, and short-acting insulin dose was reduced by 25% (A, 50% (B, and 75% (C dependent on mean exercise intensity. During exercise, BG, adrenaline, noradrenaline, dopamine, cortisol, glucagon, and insulin-like growth factor-1, blood lactate, heart rate, and gas exchange variables were measured. For 24 h after exercise, interstitial glucose was measured by continuous glucose monitoring system.BG decrease during HIIE was significantly smaller for B (p = 0.024 and tended to be smaller for A and C compared to CON. No differences were found for post-exercise interstitial glucose, acute hormone response, and carbohydrate utilization between HIIE and CON for A, B, and C. In HIIE, blood lactate for A (p = 0.006 and B (p = 0.004 and respiratory exchange ratio for A (p = 0.003 and B (p = 0.003 were significantly higher compared to CON but not for C.Hypoglycemia did not occur during or after HIIE and CON when using ultra-long-acting insulin and applying our methodological approach for exercise prescription. HIIE led to a smaller BG decrease compared to CON, although both exercises modes were matched for mean load and duration, even despite markedly higher peak workloads applied in HIIE. Therefore, HIIE and CON could be safely performed in T1DM.ClinicalTrials.gov NCT02075567 http://www.clinicaltrials.gov/ct2/show/NCT02075567.

  13. High intensity interval and moderate continuous cycle training in a physical education programme improves health-related fitness in young females

    Directory of Open Access Journals (Sweden)

    K Mazurek

    2016-04-01

    Full Text Available The aim of the study was to investigate the effects of eight weeks of regular physical education classes supplemented with high intensity interval cycle exercise (HIIE or continuous cycle exercises of moderate intensity (CME. Forty-eight collegiate females exercising in two regular physical education classes per week were randomly assigned to two programmes (HIIE; n=24 or CME; n=24 of additional (one session of 63 minutes per week physical activity for 8 weeks. Participants performed HIIE comprising 2 series of 6x10 s sprinting with maximal pedalling cadence and active recovery pedalling with intensity 65%–75% HRmax or performed CME corresponding to 65%-75% HRmax. Before and after the 8-week programmes, anthropometric data and aero- and anaerobic capacity were measured. Two-way ANOVA revealed a significant time main effect for VO2max (p<0.001, similar improvements being found in both groups (+12% in HIIE and +11% in CME, despite body mass not changing significantly (p=0.59; +0.4% in HIIE and -0.1% in CME. A significant main time effect was found for relative fat mass (FM and fat-free mass (FFM (p<0.001 and p<0.001, respectively. A group x time interaction effect was found for relative FM and FFM (p=0.018 and p=0.018; a greater reduction in FM and greater increase in FFM were noted in the CME than the HIIE group. Improvements in anaerobic power were observed in both groups (p<0.001, but it was greater in the HIIE group (interaction effect, p=0.022. Weight loss is not mandatory for exercise-induced effects on improving aerobic and anaerobic capacity in collegiate females. Eight weeks of regular physical education classes supplemented with CME sessions are more effective in improving body composition than physical education classes supplemented with HIIE sessions. In contrast to earlier, smaller trials, similar improvements in aerobic capacity were observed following physical activity with additional HIIE or CME sessions.

  14. Accuracy of Continuous Glucose Monitoring (CGM) during Continuous and High-Intensity Interval Exercise in Patients with Type 1 Diabetes Mellitus.

    Science.gov (United States)

    Moser, Othmar; Mader, Julia K; Tschakert, Gerhard; Mueller, Alexander; Groeschl, Werner; Pieber, Thomas R; Koehler, Gerd; Messerschmidt, Janin; Hofmann, Peter

    2016-08-10

    Continuous exercise (CON) and high-intensity interval exercise (HIIE) can be safely performed with type 1 diabetes mellitus (T1DM). Additionally, continuous glucose monitoring (CGM) systems may serve as a tool to reduce the risk of exercise-induced hypoglycemia. It is unclear if CGM is accurate during CON and HIIE at different mean workloads. Seven T1DM patients performed CON and HIIE at 5% below (L) and above (M) the first lactate turn point (LTP₁), and 5% below the second lactate turn point (LTP₂) (H) on a cycle ergometer. Glucose was measured via CGM and in capillary blood (BG). Differences were found in comparison of CGM vs. BG in three out of the six tests (p exercise-induced hypoglycemia, but usual BG control should be performed during intense exercise.

  15. Acute High-intensity Interval Exercise-induced Redox Signaling is Associated with Enhanced Insulin Sensitivity in Obese Middle-aged Men.

    Directory of Open Access Journals (Sweden)

    Lewan Parker

    2016-09-01

    Full Text Available Background. Obesity and ageing are associated with increased oxidative stress, activation of stress and mitogen activated protein kinases (SAPK, and the development of insulin resistance and metabolic disease. In contrast, acute exercise also increases oxidative stress and SAPK signaling, yet is reported to enhance insulin sensitivity and reduce the risk of metabolic disease. This study explored this paradox by investigating the effect of a single session of high-intensity interval-exercise (HIIE on redox status, muscle SAPK and insulin protein signaling in eleven middle-aged obese men. Methods. Participants completed a 2 hour hyperinsulinaemic-euglycaemic clamp at rest, and 60 minutes after HIIE (4x4 mins at 95% HRpeak; 2 min recovery periods, separated by 1-3 weeks. Results. Irrespective of exercise-induced changes to redox status, insulin stimulation both at rest and after HIIE similarly increased plasma superoxide dismutase activity, plasma catalase activity, and skeletal muscle 4-HNE; and significantly decreased plasma TBARS and hydrogen peroxide. The SAPK signaling pathways of p38 MAPK, NF-κB p65, and JNK, and the distal insulin signaling protein AS160Ser588, were activated with insulin stimulation at rest and to a greater extent with insulin stimulation after a prior bout of HIIE. Higher insulin sensitivity after HIIE was associated with higher insulin-stimulated SAPK phosphorylation (JNK, p38 MAPK and NF-κB and SOD activity (p<0.05. Conclusion. These findings support a role for redox homeostasis and SAPK signaling in insulin-stimulated glucose uptake which may contribute to the enhancement of insulin sensitivity in obese men 3 hours after HIIE.

  16. Comparison of Psychological and Physiological Responses to Imposed vs. Self-selected High-Intensity Interval Training.

    Science.gov (United States)

    Kellogg, Erin; Cantacessi, Cheyann; McNamer, Olivia; Holmes, Heather; von Bargen, Robert; Ramirez, Richard; Gallagher, Daren; Vargas, Stacy; Santia, Ben; Rodriguez, Karen; Astorino, Todd A

    2018-05-08

    Kellogg, E, Cantacessi, C, McNamer, O, Holmes, H, von Bargen, R, Ramirez, R, Gallagher, D, Vargas, S, Santia, B, Rodriguez, K, and Astorino, TA. Comparison of psychological and physiological responses to imposed vs. self-selected high-intensity interval training. J Strength Cond Res XX(X): 000-000, 2018-High-intensity interval training elicits similar physiological adaptations as moderate intensity continuous training (MICT). Some studies report greater enjoyment to a bout of high-intensity interval exercise (HIIE) vs. MICT, which is surprising considering that HIIE is more intense and typically imposed on the participant. This study compared physiological and perceptual responses between imposed and self-selected HIIE. Fourteen adults (age = 24 ± 3 years) unfamiliar with HIIE initially performed ramp exercise to exhaustion to measure maximal oxygen uptake (V[Combining Dot Above]O2max) followed by 2 subsequent sessions whose order was randomized. Imposed HIIE consisted of eight 60 seconds bouts at 80 percent peak power output (%PPO) separated by 60 seconds recovery at 10 %PPO. Self-selected HIIE (HIIESS) followed the same structure, but participants freely selected intensity in increments of 10 %PPO to achieve a rating of perceived exertion (RPE) ≥7. During exercise, heart rate, V[Combining Dot Above]O2, blood lactate concentration (BLa), affect (+5 to -5), and RPE were assessed. Physical Activity Enjoyment Scale was measured after exercise. Results showed higher V[Combining Dot Above]O2 (+10%, p = 0.013), BLa (p = 0.001), and RPE (p = 0.001) in HIIESS vs. HIIEIMP, and lower affect (p = 0.01), and enjoyment (87.6 ± 15.7 vs. 95.7 ± 11.7, p = 0.04). There was a significantly higher power output in self-selected vs. imposed HIIE (263.9 ± 81.4 W vs. 225.2 ± 59.6 W, p < 0.001). Data suggest that intensity mediates affective responses rather than the mode of HIIE performed by the participant.

  17. Algas vene kirjanduse nädal / Raimu Hanson

    Index Scriptorium Estoniae

    Hanson, Raimu, 1957-

    2008-01-01

    22. septembril algas Tartu Linnaraamatukogus vene kirjanduse nädal Inga Ivanova raamatu "Kadunud koerte saladus" esitlusega; 24. sept. toimub Igor Kotjuhi autoriõhtu; 26.-28. toimub Tartu Ülikoolis vene kirjandusele pühendatud rahvusvaheline teaduskonverents. Raamatukogust saab osta ka venekeelseid raamatuid

  18. Millele pöörate eluaseme ostmisel ja üürimisel tähelepanu?

    Index Scriptorium Estoniae

    2005-01-01

    Küsimusele vastavad Brüsselis tööd otsiv Kadri Kuusk, Sampo Panga koolitusosakonna juhataja Külli Meier, finantsinspektsiooni osakonnajuhataja Andre Nõmm, Riigikogu liige Meelis Atonen, Palivere lastekodu juhataja Külle Saar, Helsingis töötav arst Jaak Kiviloog, Narva kooliõpetaja Julia Ivanova, maksu- ja tolliameti peaspetsialist Tiiu Kilk

  19. International Epidemiology of Child and Adolescent Psychopathology II: Integration and Applications of Dimensional Findings from 44 Societies

    Science.gov (United States)

    Rescorla, Leslie; Ivanova, Masha Y.; Achenbach, Thomas M.; Begovac, Ivan; Chahed, Myriam; Drugli, May Britt; Emerich, Deisy Ribas; Fung, Daniel S. S.; Haider, Mariam; Hansson, Kjell; Hewitt, Nohelia; Jaimes, Stefanny; Larsson, Bo; Maggiolini, Alfio; Markovic, Jasminka; Mitrovic, Dragan; Moreira, Paulo; Oliveira, Joao Tiago; Olsson, Martin; Ooi, Yoon Phaik; Petot, Djaouida; Pisa, Cecilia; Pomalima, Rolando; da Rocha; Marina Monzani; Rudan, Vlasta; Sekulic, Slobodan; Shahini, Mimoza; de Mattos Silvares, Edwiges Ferreira; Szirovicza, Lajos; Valverde, Jose; Vera, Luis Anderssen; Villa, Maria Clara; Viola, Laura; Woo, Bernadine S. C.; Zhang, Eugene Yuqing

    2012-01-01

    Objective: To build on Achenbach, Rescorla, and Ivanova (2012) by (a) reporting new international findings for parent, teacher, and self-ratings on the Child Behavior Checklist, Youth Self-Report, and Teacher's Report Form; (b) testing the fit of syndrome models to new data from 17 societies, including previously underrepresented regions; (c)…

  20. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. Arvid Naess. Articles written in Sadhana. Volume 31 Issue 4 August 2006 pp 429-443. Estimation of failure probabilities of linear dynamic systems by importance sampling · Anna Ivanova Olsen Arvid Naess · More Details Abstract Fulltext PDF. An iterative method for estimating the failure ...

  1. Dopamine receptors genes polymorphisms in Parkinson patients with levodopa-induced dyskinesia

    NARCIS (Netherlands)

    Pozhidaev, Ivan V; Alifirova, V. M.; Freidin, Maxim B.; Zhukova, I.A.; Fedorenko, Olga Yu; Osmanova, Diana Z; Mironova, Y.S.; Wilffert, Berend; Ivanova, Svetlana A.; Loonen, Antonius

    2017-01-01

    Dopamine receptors genes polymorphisms in Parkinson patients with levodopa-induced dyskinesia I. Pozhidaev(1), V.M. Alifirova(2), M.B. Freidin(3), I.A. Zhukova(2), O.Y. Fedorenko(1), D.Z. Osmanova(1), Y.S. Mironova(2), B. Wilffert(4), S.A. Ivanova(1), A.J.M. Loonen(5) (1)Mental Health Research

  2. Structure of the Anthrax Research Literature

    Science.gov (United States)

    2006-01-01

    46 BARAKAT LA 2002 JAMA-J AM MED ASSOC 287 863 31 READ TD 2003 NATURE 423 81 96 IVANOVA N 2003 NATURE 423 87 73 SCOBIE HM 2003 P NATL ACAD SCI USA...Authors collier, rj 9; leppla, sh 7; young, jat 5; wigelsworth, dj 3; scobie , hm 3; mogridge, j 3; liu, sh 3; liddington, rc 3; lacy, db 3

  3. Effects of Different Exercise Modes on the Urinary Metabolic Fingerprint of Men with and without Metabolic Syndrome.

    Science.gov (United States)

    Siopi, Aikaterina; Deda, Olga; Manou, Vasiliki; Kellis, Spyros; Kosmidis, Ioannis; Komninou, Despina; Raikos, Nikolaos; Christoulas, Kosmas; Theodoridis, Georgios A; Mougios, Vassilis

    2017-01-26

    Exercise is important in the prevention and treatment of the metabolic syndrome (MetS), a cluster of risk factors that raises morbidity. Metabolomics can facilitate the optimization of exercise prescription. This study aimed to investigate whether the response of the human urinary metabolic fingerprint to exercise depends on the presence of MetS or exercise mode. Twenty-three sedentary men (MetS, n = 9, and Healthy, n = 14) completed four trials: resting, high-intensity interval exercise (HIIE), continuous moderate-intensity exercise (CME), and resistance exercise (RE). Urine samples were collected pre-exercise and at 2, 4, and 24 h for targeted analysis by liquid chromatography-mass spectrometry. Time exerted the strongest differentiating effect, followed by exercise mode and health status. The greatest changes were observed in the first post-exercise samples, with a gradual return to baseline at 24 h. RE caused the greatest responses overall, followed by HIIE, while CME had minimal effect. The metabolic fingerprints of the two groups were separated at 2 h, after HIIE and RE; and at 4 h, after HIIE, with evidence of blunted response to exercise in MetS. Our findings show diverse responses of the urinary metabolic fingerprint to different exercise modes in men with and without metabolic syndrome.

  4. Estimated Aerobic Capacity Changes in Adolescents with Obesity Following High Intensity Interval Exercise

    Directory of Open Access Journals (Sweden)

    Brooke E. Starkoff

    2014-07-01

    Full Text Available Vigorous aerobic exercise may improve aerobic capacity (VO2max and cardiometabolic profiles in adolescents with obesity, independent of changes to weight. Our aim was to assess changes in estimated VO2max in obese adolescents following a 6-week exercise program of varying intensities. Adolescents with obesity were recruited from an American mid-west children’s hospital and randomized into moderate exercise (MOD or high intensity interval exercise (HIIE groups for a 6-week exercise intervention, consisting of cycle ergometry for 40 minutes, 3 days per week. Heart rate was measured every two minutes during each exercise session.  Estimated VO2max measured via Åstrand cycle test, body composition, and physical activity (PA enjoyment evaluated via questionnaire were assessed pre/post-intervention. Twenty-seven adolescents (age 14.7±1.5; 17 female, 10 male completed the intervention. Estimated VO2max increased only in the HIIE group (20.0±5.7 to 22.7±6.5 ml/kg/min, p=0.015. The HIIE group also demonstrated increased PA enjoyment, which was correlated with average heart rate achieved during the intervention (r=0.55; p=0.043. Six weeks of HIIE elicited improvements to estimated VO2max in adolescents with obesity. Furthermore, those exercising at higher heart rates demonstrated greater PA enjoyment, implicating enjoyment as an important determinant of VO2max, specifically following higher intensity activities.

  5. Effects of Different Exercise Modes on the Urinary Metabolic Fingerprint of Men with and without Metabolic Syndrome

    Directory of Open Access Journals (Sweden)

    Aikaterina Siopi

    2017-01-01

    Full Text Available Exercise is important in the prevention and treatment of the metabolic syndrome (MetS, a cluster of risk factors that raises morbidity. Metabolomics can facilitate the optimization of exercise prescription. This study aimed to investigate whether the response of the human urinary metabolic fingerprint to exercise depends on the presence of MetS or exercise mode. Twenty-three sedentary men (MetS, n = 9, and Healthy, n = 14 completed four trials: resting, high-intensity interval exercise (HIIE, continuous moderate-intensity exercise (CME, and resistance exercise (RE. Urine samples were collected pre-exercise and at 2, 4, and 24 h for targeted analysis by liquid chromatography-mass spectrometry. Time exerted the strongest differentiating effect, followed by exercise mode and health status. The greatest changes were observed in the first post-exercise samples, with a gradual return to baseline at 24 h. RE caused the greatest responses overall, followed by HIIE, while CME had minimal effect. The metabolic fingerprints of the two groups were separated at 2 h, after HIIE and RE; and at 4 h, after HIIE, with evidence of blunted response to exercise in MetS. Our findings show diverse responses of the urinary metabolic fingerprint to different exercise modes in men with and without metabolic syndrome.

  6. Kakskeelse ja oraalse õppemeetodi mõju kurtide laste keelekasutusele / Kadri Hein

    Index Scriptorium Estoniae

    Hein, Kadri

    2009-01-01

    Artiklis vaadeldakse, kuidas mõjutavad kakskeelne ja oraalne õppemeetod kurtide keelekasutust. Küsitletud on Tallinna Heleni Kooli ja Tartu Hiie Kooli õpilasi. Uuriti, kuidas lapsed suhtlevad pereliikmete ja sõpradega, kuidas suheldakse väljaspool kodu, mis keelt peavad õpilased oma emakeeleks ning mis tasemel nad viipekeelt ja eesti keelt oskavad

  7. Eripedagoogid ootavad poliitilisi otsuseid / Plado, Kaja; Karlep, Karl; Ostrat, Ain; Maila, Meelika; Binsol, Hene; Kontor, Ana; küsitlenud Martin Krõlov

    Index Scriptorium Estoniae

    2007-01-01

    Eripedagoogide vestlusringis osalevad: Tartu Ülikooli eripedagoogika osakonna juhataja Kaja Plado, emeriitdotsent pedagoogikadoktor Karl Karlep, Tartu Kroonuaia Kooli direktor Ain Ostrat ja õppealajuhataja Meelike Maila, Tartu Hiie Kooli õppealajuhataja Hene Binsol ning Tartu Nõustamis- ja õpiabi keskuse juhataja Ana Kontor

  8. Ratings of Perceived Exertion and Self-reported Mood State in Response to High Intensity Interval Training. A Crossover Study on the Effect of Chronotype

    Directory of Open Access Journals (Sweden)

    Jacopo A. Vitale

    2017-07-01

    Full Text Available The aim of this study was to investigate the influence of chronotype on mood state and ratings of perceived exertion (RPE before and in response to acute high intensity interval exercise (HIIE performed at different times of the day. Based on the morningness–eveningness questionnaire, 12 morning-types (M-types; N = 12; age 21 ± 2 years; height 179 ± 5 cm; body mass 74 ± 12 kg and 11 evening-types (E-types; N = 11; age 21 ± 2 years; height 181 ± 11 cm; body mass 76 ± 11 kg were enrolled in a randomized crossover study. All subjects underwent measurements of Profile of Mood States (POMS, before (PRE, after 12 (POST12 and 24 h (POST24 the completion of both morning (08.00 am and evening (08.00 p.m. training. Additionally, Global Mood Disturbance and Energy Index (EI were calculated. RPE was obtained PRE and 30 min POST HIIE. Two-way ANOVA with Tukey’s multiple comparisons test of POMS parameters during morning training showed significant differences in fatigue, vigor and EI at PRE and POST24 between M-types and E-types. In addition, significant chronotype differences were found only in POST12 after the evening HIIE for fatigue, vigor and EI. For what concerns Borg perceived exertion, comparing morning versus evening values in PRE condition, a higher RPE was observed in relation to evening training for M-types (P = 0.0107 while E-types showed higher RPE values in the morning (P = 0.008. Finally, intragroup differences showed that E-types had a higher RPE respect to M-types before (P = 0.002 and after 30 min (P = 0.042 the morning session of HIIE. No significant changes during the evening training session were found. In conclusion, chronotype seems to significantly influence fatigue values, perceived exertions and vigor in relation to HIIE performed at different times of the day. Specifically, E-types will meet more of a burden when undertaking a physical task early in the day. Practical results suggest that performing a HIIE at those times

  9. Comparison of affective responses during and after low volume high-intensity interval exercise, continuous moderate- and continuous high-intensity exercise in active, untrained, healthy males.

    Science.gov (United States)

    Niven, Ailsa; Thow, Jacqueline; Holroyd, Jack; Turner, Anthony P; Phillips, Shaun M

    2018-09-01

    This study compared affective responses to low volume high-intensity interval exercise (HIIE), moderate-intensity continuous exercise (MICE) and high-intensity continuous exercise (HICE). Twelve untrained males ([Formula: see text] 48.2 ± 6.7 ml·kg -1 ·min -1 ) completed MICE (30 min cycle at 85% of ventilatory threshold (VT)), HICE (cycle at 105% of VT matched with MICE for total work), and HIIE (10 x 6 s cycle sprints with 60 s recovery). Affective valence and perceived activation were measured before exercise, post warm-up, every 20% of exercise time, and 1, 5, 10, and 15 min post-exercise. Affective valence during exercise declined by 1.75 ± 2.42, 1.17 ± 1.99, and 0.42 ± 1.38 units in HICE, HIIE, and MICE, respectively, but was not statistically influenced by trial (P = 0.35), time (P = 0.06), or interaction effect (P = 0.08). Affective valence during HICE and HIIE was consistently less positive than MICE. Affective valence post-exercise was not statistically influenced by trial (P = 0.10) and at 5 min post-exercise exceeded end-exercise values (P = 0.048). Circumplex profiles showed no negative affect in any trial. Affective responses to low volume HIIE are similar to HICE but remain positive and rebound rapidly, suggesting it may be a potential alternative exercise prescription.

  10. Differential Impact of Acute High-Intensity Exercise on Circulating Endothelial Microparticles and Insulin Resistance between Overweight/Obese Males and Females

    Science.gov (United States)

    Durrer, Cody; Robinson, Emily; Wan, Zhongxiao; Martinez, Nic; Hummel, Michelle L.; Jenkins, Nathan T.; Kilpatrick, Marcus W.; Little, Jonathan P.

    2015-01-01

    Background An acute bout of exercise can improve endothelial function and insulin sensitivity when measured on the day following exercise. Our aim was to compare acute high-intensity continuous exercise (HICE) to high-intensity interval exercise (HIIE) on circulating endothelial microparticles (EMPs) and insulin sensitivity in overweight/obese men and women. Methods Inactive males (BMI = 30 ± 3, 25 ± 6 yr, n = 6) and females (BMI = 28 ± 2, 21 ± 3 yr, n = 7) participated in three experimental trials in a randomized counterbalanced crossover design: 1) No exercise control (Control); 2) HICE (20 min cycling @ just above ventilatory threshold); 3) HIIE (10 X 1-min @ ∼90% peak aerobic power). Exercise conditions were matched for external work and diet was controlled post-exercise. Fasting blood samples were obtained ∼18 hr after each condition. CD62E+ and CD31+/CD42b- EMPs were assessed by flow cytometry and insulin resistance (IR) was estimated by homeostasis model assessment (HOMA-IR). Results There was a significant sex X exercise interaction for CD62E+ EMPs, CD31+/CD42b- EMPs, and HOMA-IR (all Pexercise type. There was a significant increase in HOMA-IR in males but a decrease in females following HIIE compared to Control (Pobese males and females appear to respond differently to acute bouts of high-intensity exercise. A single session of HICE and HIIE reduced circulating EMPs measured on the morning following exercise in males but in females CD62E+ EMPs were increased following HICE. Next day HOMA-IR paradoxically increased in males but was reduced in females following HIIE. Future research is needed to investigate mechanisms responsible for potential differential responses between males and females. PMID:25710559

  11. Effects of ovariectomy and exercise training intensity on energy substrate and hepatic lipid metabolism, and spontaneous physical activity in mice.

    Science.gov (United States)

    Tuazon, Marc A; Campbell, Sara C; Klein, Dylan J; Shapses, Sue A; Anacker, Keith R; Anthony, Tracy G; Uzumcu, Mehmet; Henderson, Gregory C

    2018-06-01

    Menopause is associated with fatty liver, glucose dysregulation, increased body fat, and impaired bone quality. Previously, it was demonstrated that single sessions of high-intensity interval exercise (HIIE) are more effective than distance- and duration-matched continuous exercise (CE) on altering hepatic triglyceride (TG) metabolism and very-low density lipoprotein-TG (VLDL-TG) secretion. Six weeks training using these modalities was examined for effects on hepatic TG metabolism/secretion, glucose tolerance, body composition, and bone mineral density (BMD) in ovariectomized (OVX) and sham-operated (SHAM) mice. OVX and SHAM were assigned to distance- and duration-matched CE and HIIE, or sedentary control. Energy expenditure during exercise was confirmed to be identical between CE and HIIE and both similarly reduced post-exercise absolute carbohydrate oxidation and spontaneous physical activity (SPA). OVX vs. SHAM displayed impaired glucose tolerance and greater body fat despite lower hepatic TG, and these outcomes were not affected by training. Only HIIE increased hepatic AMPK in OVX and SHAM, but neither training type impacted VLDL-TG secretion. As expected, BMD was lower in OVX, and training did not affect long bones. The results reveal intensity-dependent effects on hepatic AMPK expression and general exercise effects on subsequent SPA and substrate oxidation that is independent of estrogen status. These findings support the notion that HIIE can impact aspects of liver physiology in females while the effects of exercise on whole body substrate selection appear to be independent of training intensity. However, neither exercise approach mitigated the impairment in glucose tolerance and elevated body fat occurring in OVX mice. Copyright © 2018 Elsevier Inc. All rights reserved.

  12. Are pound and euro the same currency?

    International Nuclear Information System (INIS)

    Matsushita, Raul; Gleria, Iram; Figueiredo, Annibal; Silva, Sergio da

    2007-01-01

    Based on long-range dependence, some analysts claim that the exchange rate time series of the pound sterling and of an artificially extended euro have been locked together for years despite daily changes [M. Ausloos, K. Ivanova, Physica A 286 (2000) 353; K. Ivanova, M. Ausloos, False EUR exchange rates vs DKK, CHF, JPY and USD. What is a strong currency? in: H. Takayasu (Ed.), Empirical Sciences in Financial Fluctuations: The Advent of Econophysics, Springer-Verlag, Berlin, 2002, pp. 62-76]. They conclude that pound and euro are in practice the same currency. We assess the long-range dependence over time through Hurst exponents of pound-dollar and extended euro-dollar exchange rates employing three alternative techniques, namely rescaled range analysis, detrended fluctuation analysis, and detrended moving average. We find the result above (which is based on detrended fluctuation analysis) not to be robust to the changing techniques and parameterizing

  13. Stabilization of Lipid Membranes With Dendritic Polymers

    Science.gov (United States)

    2004-12-01

    Langmuir - Blodgett (Takamato, et al., 2001) and solution techniques (Johnson, et al., 2002). However, BLMs are too unstable to be used to make effective...J.A., Ivanova, A.T., Schwartz, D.K., Yang, T., and Cremer, P.S., 2001: Stable Ordering in Langmuir - Blodgett Films, Science, 293, 1292-1295. Tully...Various dendrimers and hyperbranched polymers were evaluated. In addition, lipids with different head groups were used to probe the underlying

  14. Genomic Analysis of Caldithrix abyssi, the Thermophilic Anaerobic Bacterium of the Novel Bacterial Phylum Calditrichaeota

    OpenAIRE

    Kublanov, Ilya V.; Sigalova, Olga M.; Gavrilov, Sergey N.; Lebedinsky, Alexander V.; Rinke, Christian; Kovaleva, Olga; Chernyh, Nikolai A.; Ivanova, Natalia; Daum, Chris; Reddy, T.B.K.; Klenk, Hans-Peter; Spring, Stefan; G?ker, Markus; Reva, Oleg N.; Miroshnichenko, Margarita L.

    2017-01-01

    © 2017 Kublanov, Sigalova, Gavrilov, Lebedinsky, Rinke, Kovaleva, Chernyh, Ivanova, Daum, Reddy, Klenk, Spring, Göker, Reva, Miroshnichenko, Kyrpides, Woyke, Gelfand, Bonch-Osmolovskaya. The genome of Caldithrix abyssi, the first cultivated representative of a phylum-level bacterial lineage, was sequenced within the framework of Genomic Encyclopedia of Bacteria and Archaea (GEBA) project. The genomic analysis revealed mechanisms allowing this anaerobic bacterium to ferment peptides or to impl...

  15. Potential biomarkers of tardive dyskinesia: A multiplex analysis of blood serum

    OpenAIRE

    Boiko, Anastasia S; Kornetova, Elena G; Ivanova, Svetlana A.; Loonen, Antonius

    2017-01-01

    Potential biomarkers of tardive dyskinesia: a multiplex analysis of blood serum A.S. Boiko(1), E.G. Kornetova(2), S.A. Ivanova(1), A.J.M. Loonen(3) (1)Mental Health Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, Laboratory of Molecular Genetics and Biochemistry, Tomsk, Russia (2)Mental Health Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, Department of Endogenous Disorders, Tomsk, Russia (3)Univers...

  16. Jazzikuu trummari joonistas 8-aastane Erik Jelle

    Index Scriptorium Estoniae

    2009-01-01

    Jazzikuu 2009 kooliõpilaste plakatikonkursist, žürii koosseis. Konkursi tulemused: 1. koht - Erik Jelle, 2. koht - Liis Hiie (Sally Stuudio Kunstikool), 3.-4. koht - Ave Auser (Tartu Kunstigümnaasium), Anett Seliin Hunt (Tallinna 21. keskkool). Sally Stuudio eripreemia - Liis Pajanen (Tallinna Pääsküla Gümnaasium). Parim töö kaunistab Jazzikuu meeneid. Näitus konkursi töödest on avatud Kristiine keskuse 2. korrusel

  17. Accuracy of Continuous Glucose Monitoring (CGM during Continuous and High-Intensity Interval Exercise in Patients with Type 1 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Othmar Moser

    2016-08-01

    Full Text Available Continuous exercise (CON and high-intensity interval exercise (HIIE can be safely performed with type 1 diabetes mellitus (T1DM. Additionally, continuous glucose monitoring (CGM systems may serve as a tool to reduce the risk of exercise-induced hypoglycemia. It is unclear if CGM is accurate during CON and HIIE at different mean workloads. Seven T1DM patients performed CON and HIIE at 5% below (L and above (M the first lactate turn point (LTP1, and 5% below the second lactate turn point (LTP2 (H on a cycle ergometer. Glucose was measured via CGM and in capillary blood (BG. Differences were found in comparison of CGM vs. BG in three out of the six tests (p < 0.05. In CON, bias and levels of agreement for L, M, and H were found at: 0.85 (−3.44, 5.15 mmol·L−1, −0.45 (−3.95, 3.05 mmol·L−1, −0.31 (−8.83, 8.20 mmol·L−1 and at 1.17 (−2.06, 4.40 mmol·L−1, 0.11 (−5.79, 6.01 mmol·L−1, 1.48 (−2.60, 5.57 mmol·L−1 in HIIE for the same intensities. Clinically-acceptable results (except for CON H were found. CGM estimated BG to be clinically acceptable, except for CON H. Additionally, using CGM may increase avoidance of exercise-induced hypoglycemia, but usual BG control should be performed during intense exercise.

  18. Exercise-intensity dependent alterations in plasma redox status do not reflect skeletal muscle redox-sensitive protein signaling.

    Science.gov (United States)

    Parker, Lewan; Trewin, Adam; Levinger, Itamar; Shaw, Christopher S; Stepto, Nigel K

    2018-04-01

    Redox homeostasis and redox-sensitive protein signaling play a role in exercise-induced adaptation. The effects of sprint-interval exercise (SIE), high-intensity interval exercise (HIIE) and continuous moderate-intensity exercise (CMIE), on post-exercise plasma redox status are unclear. Furthermore, whether post-exercise plasma redox status reflects skeletal muscle redox-sensitive protein signaling is unknown. In a randomized crossover design, eight healthy adults performed a cycling session of HIIE (5×4min at 75% W max ), SIE (4×30s Wingate's), and CMIE work-matched to HIIE (30min at 50% of W max ). Plasma hydrogen peroxide (H 2 O 2 ), thiobarbituric acid reactive substances (TBARS), superoxide dismutase (SOD) activity, and catalase activity were measured immediately post, 1h, 2h and 3h post-exercise. Plasma redox status biomarkers were correlated with phosphorylation of skeletal muscle p38-MAPK, JNK, NF-κB, and IκBα protein content immediately and 3h post-exercise. Plasma catalase activity was greater with SIE (56.6±3.8Uml -1 ) compared to CMIE (42.7±3.2, pexercise plasma TBARS and SOD activity significantly (pexercise protocol. A significant positive correlation was detected between plasma catalase activity and skeletal muscle p38-MAPK phosphorylation 3h post-exercise (r=0.40, p=0.04). No other correlations were detected (all p>0.05). Low-volume SIE elicited greater post-exercise plasma catalase activity compared to HIIE and CMIE, and greater H 2 O 2 compared to CMIE. Plasma redox status did not, however, adequately reflect skeletal muscle redox-sensitive protein signaling. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  19. Loengud seaduseelnõude koostajaile / Margit Kikas

    Index Scriptorium Estoniae

    Kikas, Margit

    2004-01-01

    Eesti Juristide Liidu poolt koostöös Riigikantselei ja Justiitsministeeriumiga korraldatud loengusarjast: Õigusloome ja normitehnika: areng ja probleemid. Sõnavõtjad loengutel: Raul Narits, Katre Kont-Kontson, Lauri Mälksoo, Raigo Sõlg, Jüri Heinla, Anno Aedmaa, Aare Kasemets, Juhani Lemmik, Ülo Siivelt, Külli Koit, Aare Reenumägi, Mall Gramberg, Toomas Sepp, Julia Laffranque, Kristel Aguraiuja, Aime Vettik, Hille Saluäär, Hiie Tamm, Kristina Nõgols, Eve Randvere

  20. Similar Anti-Inflammatory Acute Responses from Moderate-Intensity Continuous and High-Intensity Intermittent Exercise

    Directory of Open Access Journals (Sweden)

    Carolina Cabral-Santos, José Gerosa-Neto, Daniela Sayuri Inoue, Valéria Leme Gonçalves Panissa, Luís Alberto Gobbo, Alessandro Moura Zagatto, Eduardo Zapaterra Campos, Fábio Santos Lira

    2015-12-01

    Full Text Available The purpose of this study was to compare the effect of high-intensity intermittent exercise (HIIE versus volume matched steady state exercise (SSE on inflammatory and metabolic responses. Eight physically active male subjects completed two experimental sessions, a 5-km run on a treadmill either continuously (70% vVO2max or intermittently (1:1 min at vVO2max. Blood samples were collected at rest, immediately, 30 and 60 minutes after the exercise session. Blood was analyzed for glucose, non-ester fatty acid (NEFA, uric acid, lactate, cortisol, and cytokines (IL-6, IL-10 and TNF-α levels. The lactate levels exhibited higher values immediately post-exercise than at rest (HIIE 1.34 ± 0.24 to 7.11 ± 2.85, and SSE 1.35 ± 0.14 to 4.06±1.60 mmol·L-1, p 0.05. Cortisol, IL-6, IL-10 and TNF-α levels showed time-dependent changes under the different conditions (p < 0.05, however, the area under the curve of TNF-α in the SSE were higher than HIIE (p < 0.05, and the area under the curve of IL-6 in the HIIE showed higher values than SSE (p < 0.05. In addition, both exercise conditions promote increased IL-10 levels and IL-10/TNF-α ratio (p < 0.05. In conclusion, our results demonstrated that both exercise protocols, when volume is matched, promote similar inflammatory responses, leading to an anti-inflammatory status; however, the metabolic responses are different.

  1. Appetite and gut hormone responses to moderate-intensity continuous exercise versus high-intensity interval exercise, in normoxic and hypoxic conditions.

    Science.gov (United States)

    Bailey, Daniel P; Smith, Lindsey R; Chrismas, Bryna C; Taylor, Lee; Stensel, David J; Deighton, Kevin; Douglas, Jessica A; Kerr, Catherine J

    2015-06-01

    This study investigated the effects of continuous moderate-intensity exercise (MIE) and high-intensity interval exercise (HIIE) in combination with short exposure to hypoxia on appetite and plasma concentrations of acylated ghrelin, peptide YY (PYY), and glucagon-like peptide-1 (GLP-1). Twelve healthy males completed four, 2.6 h trials in a random order: (1) MIE-normoxia, (2) MIE-hypoxia, (3) HIIE-normoxia, and (4) HIIE-hypoxia. Exercise took place in an environmental chamber. During MIE, participants ran for 50 min at 70% of altitude-specific maximal oxygen uptake (V˙O2max) and during HIIE performed 6 × 3 min running at 90% V˙O2max interspersed with 6 × 3 min active recovery at 50% V˙O2max with a 7 min warm-up and cool-down at 70% V˙O2max (50 min total). In hypoxic trials, exercise was performed at a simulated altitude of 2980 m (14.5% O2). Exercise was completed after a standardised breakfast. A second meal standardised to 30% of participants' daily energy requirements was provided 45 min after exercise. Appetite was suppressed more in hypoxia than normoxia during exercise, post-exercise, and for the full 2.6 h trial period (linear mixed modelling, p  0.05). These findings demonstrate that short exposure to hypoxia causes suppressions in appetite and plasma acylated ghrelin concentrations. Furthermore, appetite responses to exercise do not appear to be influenced by exercise modality. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Endothelin-1 and Exercise Intensity in Sedentary Adolescents with Obesity

    Directory of Open Access Journals (Sweden)

    Brooke E. Starkoff

    2015-01-01

    Full Text Available Inactivity combined with obesity during adolescence increases the risk of future cardiovascular disease. The study purpose was to compare the influence of differing intensities of exercise on endothelial function in sedentary adolescents with obesity. Participants were randomized to one of two groups in a 6-week exercise intervention: moderate intensity (MOD or high intensity interval exercise (HIIE. Endothelial function was assessed pre- and post-intervention via fasted serum levels of endothelin-1 (ET-1. Pre-measures of ET-1 concentrations were elevated at baseline. No significant differences in ET-1 were found between or within exercise groups. However, in the HIIE group, ET-1 was inversely associated with percentages of age predicted maximal heart rate achieved during the intervention (p=0.035, r=-0.567. The exercise interventions did not positively change ET-1 levels, yet participants who exercised at higher intensities in the HIIE group experienced greater decreases in ET-1. Keywords: childhood obesity, endothelial function, high intensity interval exercise

  3. Impact of a single bout of high-intensity interval exercise and short-term interval training on interleukin-6, FNDC5, and METRNL mRNA expression in human skeletal muscle

    Directory of Open Access Journals (Sweden)

    Malcolm Eaton

    2018-04-01

    Full Text Available Background: Exercise promotes numerous phenotypic adaptations in skeletal muscle that contribute to improved function and metabolic capacity. An emerging body of evidence suggests that skeletal muscle also releases a myriad of factors during exercise, termed “myokines”. The purpose of this study was to examine the effects of high-intensity interval training (HIIT on the acute regulation of the mRNA expression of several myokines, including the prototypical myokine interleukin-6 (IL-6, and recently identified myokines fibronectin type III domain-containing protein 5 (FNDC5 (irisin and meteorin-like protein (METRNL. Methods: Both before and after a 20-day period of twice-daily high-volume HIIT, 9 healthy males (20.5 ± 1.5 years performed a standardized bout of high-intensity interval exercise (HIIE; 5 × 4 min at ~80% pretraining peak power output with skeletal muscle biopsy samples (vastus lateralis obtained at rest, immediately following exercise, and at 3 h recovery. Results: Before training, a single bout of HIIE increased IL-6 (p < 0.05 and METRNL (p < 0.05 mRNA expression measured at 3 h recovery when compared to rest. Following 20 days of HIIT, IL-6 and FNDC5 mRNA were increased at 3 h recovery from the standardized HIIE bout when compared to rest (both p < 0.05. Resting METRNL and FNDC5 mRNA expression were higher following training (p < 0.05, and there was an overall increase in FNDC5 mRNA post-training (main effect of training, p < 0.05. Conclusion: In human skeletal muscle (1 an acute bout of HIIE can induce upregulation of skeletal muscle IL-6 mRNA both before and after a period of intensified HIIT; (2 Resting and overall FNDC5 mRNA expression is increased by 20 days of HIIT; and (3 METRNL mRNA expression is responsive to both acute HIIE and short-term intense HIIT. Future studies are needed to confirm these findings at the protein and secretion level in humans. Keywords: Brown adipose tissue

  4. Cardiorespiratory fitness modulates the acute flow-mediated dilation response following high-intensity but not moderate-intensity exercise in elderly men.

    Science.gov (United States)

    Bailey, Tom G; Perissiou, Maria; Windsor, Mark; Russell, Fraser; Golledge, Jonathan; Green, Daniel J; Askew, Christopher D

    2017-05-01

    Impaired endothelial function is observed with aging and in those with low cardiorespiratory fitness (V̇o 2peak ). Improvements in endothelial function with exercise training are somewhat dependent on the intensity of exercise. While the acute stimulus for this improvement is not completely understood, it may, in part, be due to the flow-mediated dilation (FMD) response to acute exercise. We examined the hypothesis that exercise intensity alters the brachial (systemic) FMD response in elderly men and is modulated by V̇o 2peak Forty-seven elderly men were stratified into lower (V̇o 2peak = 24.3 ± 2.9 ml·kg -1 ·min -1 ; n = 27) and higher fit groups (V̇o 2peak = 35.4 ± 5.5 ml·kg -1 ·min -1 ; n = 20) after a test of cycling peak power output (PPO). In randomized order, participants undertook moderate-intensity continuous exercise (MICE; 40% PPO) or high-intensity interval cycling exercise (HIIE; 70% PPO) or no-exercise control. Brachial FMD was assessed at rest and 10 and 60 min after exercise. FMD increased after MICE in both groups {increase of 0.86% [95% confidence interval (CI), 0.17-1.56], P = 0.01} and normalized after 60 min. In the lower fit group, FMD was reduced after HIIE [reduction of 0.85% (95% CI, 0.12-1.58), P = 0.02] and remained decreased at 60 min. In the higher fit group, FMD was unchanged immediately after HIIE and increased after 60 min [increase of 1.52% (95% CI, 0.41-2.62), P exercise control, FMD was reduced in both groups after 60 min ( P = 0.05). Exercise intensity alters the acute FMD response in elderly men and V̇o 2peak modulates the FMD response following HIIE but not MICE. The sustained decrease in FMD in the lower fit group following HIIE may represent a signal for vascular adaptation or endothelial fatigue. NEW & NOTEWORTHY This study is the first to show that moderate-intensity continuous cycling exercise increased flow-mediated dilation (FMD) transiently before normalization of FMD after 1 h, irrespective of

  5. Computational code in atomic and nuclear quantum optics: Advanced computing multiphoton resonance parameters for atoms in a strong laser field

    Science.gov (United States)

    Glushkov, A. V.; Gurskaya, M. Yu; Ignatenko, A. V.; Smirnov, A. V.; Serga, I. N.; Svinarenko, A. A.; Ternovsky, E. V.

    2017-10-01

    The consistent relativistic energy approach to the finite Fermi-systems (atoms and nuclei) in a strong realistic laser field is presented and applied to computing the multiphoton resonances parameters in some atoms and nuclei. The approach is based on the Gell-Mann and Low S-matrix formalism, multiphoton resonance lines moments technique and advanced Ivanov-Ivanova algorithm of calculating the Green’s function of the Dirac equation. The data for multiphoton resonance width and shift for the Cs atom and the 57Fe nucleus in dependence upon the laser intensity are listed.

  6. ニヴフ語東サハリン方言の昔話テキスト : チハロシュとウサギ

    OpenAIRE

    蔡, 熙鏡

    2013-01-01

    This folktale was told by Mrs. Valentina Nikolaevna Sachgun who was born in the village Ygbo (Nogliki District) in 1935. The folktale was recorded in February 27, 2011 during my fieldwork in the village of Nogliki. Then I transcribed the folktale with the help of Mrs. Galina Ivanova Paklina, another speaker of the East-Sakhalin Dialect of Nivkh, in September 14, 2012. Caror and Rabbit In the old days, People took some of rabbit skins and brought it with them when they go to Pot...

  7. High-intensity intermittent exercise and its effects on heart rate variability and subsequent strength performance

    Directory of Open Access Journals (Sweden)

    Valéria Leme Gonçalves Panissa

    2016-03-01

    Full Text Available PRUPOSE: To investigate the effects of a 5-km high-intensity interval exercise (HIIE on heart rate variability (HRV and subsequent strength performance. METHODS: nine trained males performed a control session composed of a half-squat strength exercise (4 x 80% of one repetition maximum – 1RM in isolation and 30-min, 1-, 4-, 8- and 24-h after an HIIE (1-min at the velocity peak:1-min passive recovery. All experimental sessions were performed on different days. The maximum number of repetitions and total weight lifted during the strength exercise were registered in all conditions; in addition, prior to each session, HRV were assessed [beat-to-beat intervals (RR and log-transformed of root means square of successive differences in the normal-to-normal intervals (lnRMSSD]. RESULTS: Performance in the strength exercise dropped at 30-min (31% and 1-h (19% post-HIIE concomitantly with lower values of RR (781±79 ms; 799±134 ms, respectively in the same recovery intervals compared to the control (1015±197 ms. Inferential analysis did not detect any effect of condition on lnRMSSD, however, values were lower after 30-min (3.5±0.4 ms and 1-h (3.3±0.5 ms with moderate and large effect sizes (0.9 and 1.2, respectively compared with the control condition (3.9±0.4 ms. CONCLUSION: Both RR and lnRMSSD seem to be associated with deleterious effects on strength performance, although further studies should be conducted to clarify this association.

  8. The effect of a lifestyle intervention on metabolic health in young women

    Directory of Open Access Journals (Sweden)

    Dunn SL

    2014-09-01

    Full Text Available Sarah L Dunn,1 Winnie Siu,2 Judith Freund,2,3 Stephen H Boutcher2 1Department of Kinesiology, University of La Verne, CA, USA; 2School of Medical Sciences, Faculty of Medicine, University of New South Wales, NSW, Australia; 3St Vincent's Hospital, NSW, Australia Abstract: With the increasing obesity rates in Western countries, an effective lifestyle intervention for fat reduction and metabolic benefits is needed. High-intensity intermittent exercise (HIIE, Mediterranean eating habits (Mediet, and fish oil (ω-3 consumption positively impact metabolic health and adiposity, although the combined effect has yet to be determined. A 12-week lifestyle intervention on adiposity, insulin resistance, and interleukin-6 (IL-6 levels of young overweight women was administered. Thirty women with a body mass index of 26.6±0.5 kg/m2, blood pressure of 114/66±1.9/1.5 mmHg, and age of 22±0.8 years were randomly assigned to either an intervention group receiving Mediet advice, daily ω-3 supplementation, and HIIE 3 days/week for 12 weeks or a control group. The group receiving Mediet advice, daily ω-3 supplementation, and HIIE experienced a significant reduction in total body fat mass (P<0.001, abdominal adiposity (P<0.05, waist circumference (P<0.001, systolic blood pressure (P<0.05, fasting plasma insulin (P<0.05, IL-6 (P<0.001, and triglycerides (P<0.05. The greatest decreases in fasting plasma insulin (P<0.05 and IL-6 (P<0.001 occurred by week 6 of the intervention. Significant improvements in eating habits (P<0.05 and aerobic fitness (P<0.001 were also found following the intervention. A multifaceted 12-week lifestyle program comprising a Mediet, ω-3 supplementation, and HIIE induced significant improvements in fat loss, aerobic fitness, and insulin and IL-6 levels, positively influencing metabolic health. Keywords: metabolic syndrome, overweight, exercise, diet

  9. Irisin in response to exercise in humans with and without metabolic syndrome.

    Science.gov (United States)

    Huh, Joo Young; Siopi, Aikaterina; Mougios, Vassilis; Park, Kyung Hee; Mantzoros, Christos S

    2015-03-01

    Irisin is a recently identified exercise-induced myokine. However, the circulating levels of irisin in response to different types of exercise in subjects with metabolic syndrome are unknown. This study aimed to study the levels of irisin in healthy males and subjects with metabolic syndrome at baseline and in response to exercise. Each individual completed high-intensity interval exercise (HIIE), continuous moderate-intensity exercise (CME), and resistance exercise (RE) sessions in a random, crossover design. Percentage change in circulating irisin levels was examined. Two different irisin assays were used to compare the results of the RE study. Circulating irisin increased immediately after HIIE, CME, and RE and declined 1 hour later. The increase was greater in response to resistance compared with either high-intensity intermittent exercise or CME. Change in irisin in response to exercise did not differ between individuals with and without metabolic syndrome. Exercise is able to increase circulating irisin levels in individuals with the metabolic syndrome as well as healthy individuals. Whether this increase may contribute to the beneficial effects of exercise on patients with the metabolic syndrome remains to be studied further.

  10. Acute Low-Volume High-Intensity Interval Exercise and Continuous Moderate-Intensity Exercise Elicit a Similar Improvement in 24-h Glycemic Control in Overweight and Obese Adults.

    Science.gov (United States)

    Parker, Lewan; Shaw, Christopher S; Banting, Lauren; Levinger, Itamar; Hill, Karen M; McAinch, Andrew J; Stepto, Nigel K

    2016-01-01

    Background: Acute exercise reduces postprandial oxidative stress and glycemia; however, the effects of exercise intensity are unclear. We investigated the effect of acute low-volume high-intensity interval-exercise (LV-HIIE) and continuous moderate-intensity exercise (CMIE) on glycemic control and oxidative stress in overweight and obese, inactive adults. Methods: Twenty-seven adults were randomly allocated to perform a single session of LV-HIIE (9 females, 5 males; age: 30 ± 1 years; BMI: 29 ± 1 kg·m -2 ; mean ± SEM) or CMIE (8 females, 5 males; age: 30 ± 2.0; BMI: 30 ± 2.0) 1 h after consumption of a standard breakfast. Plasma redox status, glucose and insulin were measured. Continuous glucose monitoring (CGM) was conducted during the 24-h period before (rest day) and after exercise (exercise day). Results: Plasma thiobarbituric acid reactive substances (TBARS; 29 ±13%, p improvement in 24-h average glucose levels (-5 ± 2%, p improving 24-h glycemic control in overweight and obese adults.

  11. Global Metabolic Stress of Isoeffort Continuous and High Intensity Interval Aerobic Exercise: A Comparative 1H NMR Metabonomic Study.

    Science.gov (United States)

    Zafeiridis, Andreas; Chatziioannou, Anastasia Chrysovalantou; Sarivasiliou, Haralambos; Kyparos, Antonios; Nikolaidis, Michalis G; Vrabas, Ioannis S; Pechlivanis, Alexandros; Zoumpoulakis, Panagiotis; Baskakis, Constantinos; Dipla, Konstantina; Theodoridis, Georgios A

    2016-12-02

    The overall metabolic/energetic stress that occurs during an acute bout of exercise is proposed to be the main driving force for long-term training adaptations. Continuous and high-intensity interval exercise protocols (HIIE) are currently prescribed to acquire the muscular and metabolic benefits of aerobic training. We applied 1 H NMR-based metabonomics to compare the overall metabolic perturbation and activation of individual bioenergetic pathways of three popular aerobic exercises matched for effort/strain. Nine men performed continuous, long-interval (3 min), and short-interval (30 s) bouts of exercise under isoeffort conditions. Blood was collected before and after exercise. The multivariate PCA and OPLS-DA models showed a distinct separation of pre- and postexercise samples in three protocols. The two models did not discriminate the postexercise overall metabolic profiles of the three exercise types. Analysis focused on muscle bioenergetic pathways revealed an extensive upregulation of carbohydrate-lipid metabolism and the TCA cycle in all three protocols; there were only a few differences among protocols in the postexercise abundance of molecules when long-interval bouts were performed. In conclusion, continuous and HIIE exercise protocols, when performed with similar effort/strain, induce comparable global metabolic response/stress despite their marked differences in work-bout intensities. This study highlights the importance of NMR metabonomics in comprehensive monitoring of metabolic consequences of exercise training in the blood of athletes and exercising individuals.

  12. Glucose response to exercise in the post-prandial period is independent of exercise intensity.

    Science.gov (United States)

    Shambrook, P; Kingsley, M I; Wundersitz, D W; Xanthos, P D; Wyckelsma, V L; Gordon, B A

    2018-03-01

    This study investigated the acute glucose response to low-intensity, moderate-intensity, and high-intensity interval exercise compared to no-exercise in healthy insufficiently active males using a four-arm, randomized, crossover design. Ten males (age: 37.3 ± 7.3 years, BMI: 29.3 ± 6.5 kg·m -2 ) completed four 30-minute interventions at weekly intervals comprising low-intensity exercise (LIE) at ~35% V˙O 2 R, moderate-intensity exercise (MIE) at ~50% V˙O 2 R, high-intensity interval exercise (HIIE) at ~80% V˙O 2 R, and a no-exercise control. Participants performed cycle ergometer exercise 30 minutes after finishing breakfast. Glucose response was assessed using a continuous glucose monitor under free-living conditions with dietary intake replicated. A significant effect for intensity on energy expenditure was identified (P exercise trial. Glucose response was not different between exercise intensities (P > .05). Twenty-four-hour AUC was not affected by exercise intensity (P = .75). There was a significant effect for exercise enjoyment (P = .02), with LIE (69 ± 4) preferred less than HIIE (mean ± SD: 84 ± 14; P = .02), MIE (73 ± 5; P = .03), and no-exercise (75 ± 4; P = .03). Exercise at any intensity 30 minutes after a meal affects glycemic regulation equally in insufficiently active males. Moderate to vigorous exercise intensities were preferred, and therefore, the exercise guidelines appear appropriate for the prevention of cardiometabolic disease. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. PREFACE: INERA Workshop: Transition Metal Oxide Thin Films-functional Layers in "Smart windows" and Water Splitting Devices. Parallel session of the 18th International School on Condensed Matter Physics

    Science.gov (United States)

    2014-11-01

    The Special issue presents the papers for the INERA Workshop entitled "Transition Metal Oxides as Functional Layers in Smart windows and Water Splitting Devices", which was held in Varna, St. Konstantin and Elena, Bulgaria, from the 4th-6th September 2014. The Workshop is organized within the context of the INERA "Research and Innovation Capacity Strengthening of ISSP-BAS in Multifunctional Nanostructures", FP7 Project REGPOT 316309 program, European project of the Institute of Solid State Physics at the Bulgarian Academy of Sciences. There were 42 participants at the workshop, 16 from Sweden, Germany, Romania and Hungary, 11 invited lecturers, and 28 young participants. There were researchers present from prestigious European laboratories which are leaders in the field of transition metal oxide thin film technologies. The event contributed to training young researchers in innovative thin film technologies, as well as thin films characterization techniques. The topics of the Workshop cover the field of technology and investigation of thin oxide films as functional layers in "Smart windows" and "Water splitting" devices. The topics are related to the application of novel technologies for the preparation of transition metal oxide films and the modification of chromogenic properties towards the improvement of electrochromic and termochromic device parameters for possible industrial deployment. The Workshop addressed the following topics: Metal oxide films-functional layers in energy efficient devices; Photocatalysts and chemical sensing; Novel thin film technologies and applications; Methods of thin films characterizations; From the 37 abstracts sent, 21 manuscripts were written and later refereed. We appreciate the comments from all the referees, and we are grateful for their valuable contributions. Guest Editors: Assoc. Prof. Dr.Tatyana Ivanova Prof. DSc Kostadinka Gesheva Prof. DSc Hassan Chamatti Assoc. Prof. Dr. Georgi Popkirov Workshop Organizing Committee Prof

  14. Bulgarians@cern.ch

    CERN Multimedia

    2000-01-01

    The happy Bulgarian family. From left to right, last row to first row: Ilka Antcheva, Georgi Antchev, Dimitri Borilkov, Ivana Hristova, Petiu Petev, Peicho Petkov, Borislav Pavlov, Peter Hristov, Mihail Tchijov, Stefan Piperov, Ekaterina Ivanova, Dimitar Kolev, Roumen Tzenov. Bobby is striding along with his white sneakers, black trousers belted high at the waist and a blue shirt buttoned up to the top. He comes to the coffee table and sits down on the chair crossing his legs. While speaking he fiddles with his glasses and his black curly hair dangles on the sides of his head. Borislav Pavlov or Bobby is a 22 year old Bulgarian summer Physics student at Sofia University and came to CERN to work on ORCA reconstruction software for the CMS experiment. “I will do my thesis on ORCA and it is so good that I can be here, work here where the projects actually happen and exchange experience with the people working here,” he says. “It is an honor for me.” Bulgaria joined CERN as a member state in 1999 but Bulgar...

  15. ANTISTAPHYLOCOCCAL ACTIVITY OF LIPOSOMAL FORMS OF LINCOMYCIN

    Directory of Open Access Journals (Sweden)

    Derkach SA

    2015-04-01

    Full Text Available Nowadays the vital problem of modern medicine is a tendency to emerging of both nosocomial and community-acquired strains before antibiotic resistance forming. The complexity of antibiotic therapy of diseases caused by methicillin resistant staphylococci having high poly resistance almost to every classes of antibacterial agents is of prime importance. One of the ways to improve antibacterial preparations still remains the development of their liposomal forms. This work studies antistaphylococcal activity (according to MIC of the liposomal form of lincomycin developed in the Institute of Dermatology and Venereology of Ukraine by Ivanova N. N., the Candidate of Сhemical Sciences.The purpose of this research work was to study liposomal inhibiting concentration of the liposomalny form of lincomycin and a commercial preparation lincomycin (produced by CJSC “Pharmaceutical firm "Darnitsa". Determination of the minimum inhibiting concentration was carried out by a tablet micromethod by consecutive cultivations of the samples under study.It is shown that MIC of liposomal lincomycin is eight times as low as usual lincomycin (0,23mkg/ml to 1,87 mkg/ml. Antibacterial activity of the liposomal form of lincomycin is studied concerning the patients selected from the different biotopes with pyo inflammatory diseases of staphylococcus strains (15 strains – methicillin sensitive, 12 strains - methicillin resistant.It is shown authentically the higher sensitivity of S. aureus strains to the liposomal form of lincomycin in comparison with usual lincomycin . Also 50.0% of MRSA strains were sensitive to the liposomalny form of lincomycin that shows the perspective for the development of the liposomal forms of antibiotics to cure staphylococcal infections.

  16. Policies and Processes for Social Inclusion: Using EquiFrame and EquIPP for Policy Dialogue Comment on "Are Sexual and Reproductive Health Policies Designed for All? Vulnerable Groups in Policy Documents of Four European Countries and Their Involvement in Policy Development".

    Science.gov (United States)

    MacLachlan, Malcolm; Mannan, Hasheem; Huss, Tessy; Munthali, Alister; Amin, Mutamad

    2015-11-16

    The application of EquiFrame in the analysis of sexual and reproductive health policies by Ivanova et al to a new thematic area, their selection of only some of the Core Concepts of human rights in health service provision and the addition of new vulnerable groups relevant to the purpose of their analysis, are all very welcome developments. We also applaud their application of EquiFrame to policies in countries where it has not previously been used, along with their use of interviews with policy-makers to produce a deeper understanding of policy processes. We argue that clear justification for the inclusion of additional, or replacement of some exiting vulnerable groups within EquiFrame should be accompanied by clear definitions of such groups, along with the evidence-base that justifies their classification as a vulnerable or marginalised group. To illustrate the versatility of EquiFrame, we summarise a range of ways in which it has been used across a number of regions; including a brief Case Study of its use to develop the National Health Policy of Malawi. While EquiFrame focuses on policy content, we preview a new policy analysis tool - Equity and Inclusion in Policy Processes (EquIPP) - which assesses the extent of equity and inclusion in broader policy processes. Together, EquiFrame and EquIPP can be used to help governments and civil society ensure that policies are addressing the much stronger emphasis on social inclusion, now apparent in the Sustainable Development Goals (SDGs). © 2016 by Kerman University of Medical Sciences.

  17. Association of preoperative levels of selected blood inflammatory markers with prognosis in gliomas

    Directory of Open Access Journals (Sweden)

    Auezova R

    2016-10-01

    Full Text Available Raushan Auezova,1 Nurzhan Ryskeldiev,1 Aidos Doskaliyev,1 Yerbol Kuanyshev,1 Berik Zhetpisbaev,1 Nurgul Aldiyarova,1 Natalia Ivanova,2 Serik Akshulakov,1 Lizette Auezova3 1Department of Pathology of the Central Nervous System, National Centre for Neurosurgery, Astana, Kazakhstan; 2Polenov Russian Scientific Research Institute of Neurosurgery (a branch of Federal Almazov North-West Medical Research Centre, Ministry of Health of the Russian Federation, Saint-Petersburg, Russia; 3Bioactive Molecules Research Group, Department of Chemistry and Biochemistry, Faculty of Sciences-II, Lebanese University, Beirut, Lebanon Background: Red cell distribution width (RDW, neutrophil–lymphocyte ratio (NLR, and platelet count (PLT routinely tested as part of the complete blood count are indicative of systemic inflammation. The prognostic significance of NLR and PLT in cancer was demonstrated in many studies while the role of RDW has been hardly investigated. The present study aimed to assess the association of RDW, NLR, and PLT with survival and tumor grade in glioma patients. Methods: Clinical data from 178 patients with primary gliomas treated in a single institution were retrospectively analyzed. Receiver operating characteristic curves for cutoff value determination, Kaplan–Meier survival analysis, various bivariate tests, and univariate and multivariate Cox regression analyses were performed. Results: Patients with high RDW (≥13.95 and NLR (≥4 levels had worse overall survival (OS (Wilcoxon test, P<0.026 and P<0.003, respectively while the effect of thrombocytosis (≥400×109/L on prognosis was not significant. Besides, a strong association between RDW and NLR was found (Spearman’s rho =0.230, P<0.02; χ2=8.887, P<0.03; Mann–Whitney U-test, P<0.017. Moreover, RDW and NLR were significantly associated with tumor grade. In univariate Cox analysis, elevated NLR (hazard ratio, HR 1.385; confidence interval, CI 1.020–1.881, P<0.037, older age

  18. Basic Principles and Practices of Integrated Dosimetric Passportization of the Settlements in Ukraine.

    Science.gov (United States)

    Likhtarov, I A; Kovgan, L M; Masiuk, S V; Ivanova, O M; Chepurny, M I; Boyko, Z N; Gerasymenko, V B

    2015-12-01

    of important radiological parameters, namely over 500 thousands of measurements of concentration of 137Cs and 90Sr in the local foodstuff (milk and potatoes); there are more than 1.3 million of measurements of the cesium content in the body of residents of the settlements of Ukraine; there are 100 thousands of dose estimates (both internal and external ones were measured separately) of inhabitants living on the radioactively contaminated areas. The results of the dosimetric passportization served as one of the main exposure criteria for generalized aftermath of the Chornobyl accident represented in the National reports for the first 15, 20 and 25 years after the accident. I. A. Likhtarov, L. M. Kovgan, S. V. Masiuk, O. M. Ivanova, M. I. Chepurny.

  19. Analytical chemistry in nuclear science and technology: a scientometric mapping

    International Nuclear Information System (INIS)

    Kademani, B.S.; Kumar, Anil; Kumar, Vijai

    2007-01-01

    This paper attempts to analyse quantitatively the growth and development of Analytical Chemistry research in Nuclear Science and Technology in terms of publication output as reflected in International Nuclear Information System (INIS) database (1970-2005). During 1970-2005 a total of 8224 papers were published. There were only seven papers published in 1970. Thereafter, a tremendous explosion of literature was observed in this area. The highest number of papers (636) were published in 1985. The average number of publications published per year was 228.44. United States topped the list with 1811 publications followed by USSR with 1688 publications, Germany with 777 publications, India with 730 publications and Hungary with 519 publications. Authorship and collaboration trend was towards multi-authored papers as 80.3 percent of the papers were collaborative is indicative of the multidisciplinary nature of research activity. The most prolific authors were: B. F. Myasoedov, AN SSSR Moscow Inst. Geokhimii I Analitisheskoi Khimii, Russian Federation with 84 publications, M. Sudersanan, Bhabha Atomic Research Centre, Mumbai, India with 67 publications, P.Vanura and V. Jedinakova Krizova both from Institute of Chemical Technology, Prague, Czech Republic with 54 publications each, S. Gangadharan, Bhabha Atomic Research Centre, Mumbai, India with 47 publications, V.M. Ivanova , M.V. Lomonosov Moscow State University, Russian Federation with 45 publications and Yu. A Zolotov Lomonosov Moscow State University, Russian Federation with 40 publications. The journals most preferred by the scientists for publication of papers were : Zhurnal Analiticheskoj Khimii with 713 papers, Journal of Radioanalytical and Nuclear Chemistry with 409 papers, Analytical Chemistry Washington with 364 papers, Fresenius' Journal of Analytical Chemistry with 324 papers, Indian Journal of Chemistry, Section A with 251 papers, and Journal of Analytical Chemistry of the USSR with 145 papers. The high

  20. 8-isorpostanes – markers for oxidative stress in obstructive sleep apnea patients with systolic dysfunction

    Directory of Open Access Journals (Sweden)

    Cherneva RV

    2013-06-01

    Full Text Available Radostina Vlaeva Cherneva,1 Ognian Borisov Georgiev,1 Daniela Stoichkova Petrova,1 Emil Ivanov Manov,2 Sylvia Rumenova Ruseva,3 Vanio Ivanov Mitev,3 Julia Ivanova Petrova4 1Department of Internal Medicine, Division of Pulmonary Medicine, Medical University of Sofia, Sofia, Bulgaria; 2Department of Internal Medicine, Division of Cardiology, Medical University of Sofia, Sofia, Bulgaria; 3Department of Medical Chemistry and Biochemistry, Laboratory of Synthesis and Analysis of Bioactive Substances, Medical University of Sofia, Sofia, Bulgaria; 4Department of Neurology, Medical University of Sofia, Sofia, Bulgaria Objective: Increased oxidative stress is considered to be an independent risk factor for cardiovascular diseases, but remains disputed in obstructive sleep apnea (OSA. Among oxidative stress markers, isorpostanes are considered to be the most sensitive and specific. Aims: The aim of the study was to compare urinary isorpostanes in patients with OSA and systolic dysfunction to patients with OSA and preserved ejection fraction (EF and determine their role as markers for increased oxidative stress and early cardiac damage. Materials and methods: Urinary 8F2-isorpostanes were measured in 30 patients with OSA and mild systolic dysfunction (EF = 45.7% ± 6.17% and compared to 15 patients with OSA and normal EF (EF = 60.3% ± 6.3%. Univariate regression analysis was performed to find predictors of left systolic dysfunction. Correlations between 8-isorpostanes, anthropometric, metabolic, and sleep study characteristics were explored. In addition, in 19 patients the effect of bilevel positive airway pressure (BiPAP therapy was evaluated during a 3 month follow-up. Markers of hemodynamic stress, N-terminal prohormone of brain natriuretic peptide and oxidative stress, measured by 8-isorpostanes were compared before and after the follow-up. Results: Urinary levels of 8-isorpostanes were significantly higher in the group with mild systolic dysfunction

  1. Overview of Experiments for Physics of Fast Reactors from the International Handbooks of Evaluated Criticality Safety Benchmark Experiments and Evaluated Reactor Physics Benchmark Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Bess, J. D.; Briggs, J. B.; Gulliford, J.; Ivanova, T.; Rozhikhin, E. V.; Semenov, M. Yu.; Tsibulya, A. M.; Koscheev, V. N.

    2017-07-01

    Overview of Experiments to Study the Physics of Fast Reactors Represented in the International Directories of Critical and Reactor Experiments John D. Bess Idaho National Laboratory Jim Gulliford, Tatiana Ivanova Nuclear Energy Agency of the Organisation for Economic Cooperation and Development E.V.Rozhikhin, M.Yu.Sem?nov, A.M.Tsibulya Institute of Physics and Power Engineering The study the physics of fast reactors traditionally used the experiments presented in the manual labor of the Working Group on Evaluation of sections CSEWG (ENDF-202) issued by the Brookhaven National Laboratory in 1974. This handbook presents simplified homogeneous model experiments with relevant experimental data, as amended. The Nuclear Energy Agency of the Organization for Economic Cooperation and Development coordinates the activities of two international projects on the collection, evaluation and documentation of experimental data - the International Project on the assessment of critical experiments (1994) and the International Project on the assessment of reactor experiments (since 2005). The result of the activities of these projects are replenished every year, an international directory of critical (ICSBEP Handbook) and reactor (IRPhEP Handbook) experiments. The handbooks present detailed models of experiments with minimal amendments. Such models are of particular interest in terms of the settlements modern programs. The directories contain a large number of experiments which are suitable for the study of physics of fast reactors. Many of these experiments were performed at specialized critical stands, such as BFS (Russia), ZPR and ZPPR (USA), the ZEBRA (UK) and the experimental reactor JOYO (Japan), FFTF (USA). Other experiments, such as compact metal assembly, is also of interest in terms of the physics of fast reactors, they have been carried out on the universal critical stands in Russian institutes (VNIITF and VNIIEF) and the US (LANL, LLNL, and others.). Also worth mentioning

  2. CYTOKINES AND HERPESVIRUSES IN CHILDREN WITH MULTIPLE SCLEROSIS

    Directory of Open Access Journals (Sweden)

    G. F. Zheleznikova

    2015-01-01

    Full Text Available It was determined earlier (G.P. Ivanova, 2012 that a chronic course of leukoencephalitis in teenagers caused by inadequate response of cytokine system to the combination of two herpesviruses (HV — EBV and HHV-6, leads to the development of multiple sclerosis (MS in 44% of cases. The research objective was to characterize the cytokine response in children with MS with simultaneous screening of the presence of active HV infections. 39 children with the diagnosis “MS” were under observation, 34 of them had relapsing-remitting (RR MS, and 5 children had a progressing course of MS (PMS. Concentration of cytokines IL-1β, IL-6, IL-8, IL-10, IFNα, IFNγ, and IL-4 was identified in blood serum and cerebrospinal liquid (CSF by enzyme-linked immunosorbent assay, HV DNA was revealed by PCR. Cytokine status in children with MS had some differences depending on the phase of the disease, clinical severity of the relapse and the course of MS. The relapse phase of RRMS was associated with the accumulation of IL-8, IL-10, and IL-6 in the blood, and index IFNγ/IL-4 modulations in accordance with the clinical severity of the relapse. A severe aggravation of the disease in children with PMS was accompanied by the increase of IL-8 system response. HV DNA was revealed in 27 patients from 39 ones (69% in blood and in 17 patients (44% in CSF with the predominance of EBV (93%, frequently in combination with HHV-6. During an acute period the frequency of HV DNA identification increased 2–3 times to compare with the remission period. Unlike children with RRMS, a mixed-infection of 3–4 herpes viruses was revealed in all 5 patients with PMS. According to the results summary it is possible to make a conclusion that HV-infection has an important role in MS pathogenesis in teenagers, taking part in the aggravation and progression of the disease by its effect on the cytokine system response. EBV-infection dominates among HV, however the risk of MS development

  3. Methods and approaches to provide feedback from nuclear and covariance data adjustment for improvement of nuclear data files. SG39 meeting, November 2014

    International Nuclear Information System (INIS)

    Aufiero, Manuele; Ivanov, Evgeny; Hoefer, Axel; Yokoyama, Kenji; Da Cruz, Dirceu Ferreira; KODELI, Ivan-Alexander; Hursin, Mathieu; Pelloni, Sandro; Palmiotti, Giuseppe; Salvatores, Massimo; Barnes, Andrew; Cabellos De Francisco, Oscar; ); Ivanova, Tatiana; )

    2014-11-01

    The aim of WPEC subgroup 39 'Methods and approaches to provide feedback from nuclear and covariance data adjustment for improvement of nuclear data files' is to provide criteria and practical approaches to use effectively the results of sensitivity analyses and cross section adjustments for feedback to evaluators and differential measurement experimentalists in order to improve the knowledge of neutron cross sections, uncertainties, and correlations to be used in a wide range of applications. This document is the proceedings of the third formal Subgroup meeting held at the NEA, Issy-les-Moulineaux, France, on 27-28 November 2014. It comprises a Summary Record of the meeting and all the available presentations (slides) given by the participants: A - Sensitivity methods: 1 - Perturbation/sensitivity calculations with Serpent (M. Aufiero); 2 - Comparison of deterministic and Monte Carlo sensitivity analysis of SNEAK-7A and FLATTOP-Pu Benchmarks (I. Kodeli); B - Integral experiments: 1 - PROTEUS experiments: selected experiments sensitivity profiles and availability, (M. Hursin, M. Salvatores - PROTEUS Experiments, HCLWR configurations); 2 - SINBAD Benchmark Database and FNS/JAEA Liquid Oxygen TOF Experiment Analysis (I. Kodeli); 3 - STEK experiment Opportunity for Validation of Fission Products Nuclear Data (D. Da Cruz); 4 - SEG (tailored adjoint flux shapes) (M. Savatores - comments) 5 - IPPE transmission experiments (Fe, 238 U) (T. Ivanova); 6 - RPI semi-integral (Fe, 238 U) (G. Palmiotti - comments); 7 - New experiments, e.g. in connection with the new NSC Expert Group on 'Improvement of Integral Experiments Data for Minor Actinide Management' (G. Palmiotti - Some comments from the Expert Group) 8 - Additional PSI adjustment studies accounting for nonlinearity (S. Pelloni); 9 - Adjustment methodology issues (G. Palmiotti); C - Am-241 and fission product issues: 1 - Am-241 validation for criticality-safety calculations (A. Barnes - Visio

  4. Methods and approaches to provide feedback from nuclear and covariance data adjustment for improvement of nuclear data files. SG39 meeting, May 2014

    International Nuclear Information System (INIS)

    Aliberti, G.; Archier, P.; Dunn, M.; Dupont, E.; Hill, I.; ); Garcia, A.; Hursin, M.; Pelloni, S.; Ivanova, T.; Kodeli, I.; Palmiotti, G.; Salvatores, M.; Touran, N.; Wenming, Wang; Yokoyama, K.

    2014-05-01

    The aim of WPEC subgroup 39 'Methods and approaches to provide feedback from nuclear and covariance data adjustment for improvement of nuclear data files' is to provide criteria and practical approaches to use effectively the results of sensitivity analyses and cross section adjustments for feedback to evaluators and differential measurement experimentalists in order to improve the knowledge of neutron cross sections, uncertainties, and correlations to be used in a wide range of applications. This document is the proceedings of the second Subgroup meeting, held at the NEA, Issy-les-Moulineaux, France, on 13 May 2014. It comprises a Summary Record of the meeting and all the available presentations (slides) given by the participants: A - Welcome: Review of actions (M. Salvatores); B - Inter-comparison of sensitivity coefficients: 1 - Sensitivity Computation with Monte Carlo Methods (T. Ivanova); 2 - Sensitivity analysis of FLATTOP-Pu (I. Kodeli); 3 - Sensitivity coefficients by means of SERPENT-2 (S. Pelloni); 4 - Demonstration - Database for ICSBEP (DICE) and Database and Analysis Tool for IRPhE (IDAT) (I. Hill); C - Specific new experiments: 1 - PROTEUS FDWR-II (HCLWR) program summary (M. Hursin); 2 - STEK and SEG Experiments, M. Salvatores 3 - Experiments related to "2"3"5U, "2"3"8U, "5"6Fe and "2"3Na, G. Palmiotti); 4 - Validation of Iron Cross Sections against ASPIS Experiments (JEF/DOC-420) (I. Kodeli); 5 - Benchmark analysis of Iron Cross-sections (EFFDOC-1221) (I. Kodeli 6 - Integral Beta-effective Measurements (K. Yokoyama on behalf of M. Ishikawa); D - Adjustment results: 1 - Impacts of Covariance Data and Interpretation of Adjustment Trends of ADJ2010, (K. Yokoyama); 2 - Revised Recommendations from ADJ2010 Adjustment (K. Yokoyama); 3 - Comparisons and Discussions on Adjustment trends from JEFF (CEA) (P. Archier); 4 - Feedback on CIELO Isotopes from ENDF/B-VII.0 Adjustment (G. Palmiotti); 5 - Demonstration - Plot comparisons of participants' results (E

  5. Unified Access Architecture for Large-Scale Scientific Datasets

    Science.gov (United States)

    Karna, Risav

    2014-05-01

    data formats have been anticipated and considered during the design of the unified architecture. The research focuses on the feasibility of the designed coupling mechanism and the evaluation of the efficiency and benefits of our proposed unified access architecture. Zhang 2011: Zhang, Ying and Kersten, Martin and Ivanova, Milena and Nes, Niels, SciQL: Bridging the Gap Between Science and Relational DBMS, Proceedings of the 15th Symposium on International Database Engineering Applications, 2011. Baumann 98: Baumann, P., Dehmel, A., Furtado, P., Ritsch, R., Widmann, N., "The Multidimensional Database System RasDaMan", SIGMOD 1998, Proceedings ACM SIGMOD International Conference on Management of Data, June 2-4, 1998, Seattle, Washington, 1998. hadoop1: hadoop.apache.org, "Hadoop", http://hadoop.apache.org/, [Online; accessed 12-Jan-2014]. scalapack1: netlib.org/scalapack, "ScaLAPACK", http://www.netlib.org/scalapack,[Online; accessed 12-Jan-2014]. r1: r-project.org, "R", http://www.r-project.org/,[Online; accessed 12-Jan-2014]. matlab1: mathworks.com, "Matlab Documentation", http://www.mathworks.de/de/help/matlab/,[Online; accessed 12-Jan-2014]. scidbusr1: scidb.org, "SciDB User's Guide", http://scidb.org/HTMLmanual/13.6/scidb_ug,[Online; accessed 01-Dec-2013].

  6. Rolled lawn as tool for industrial barren remediation

    Science.gov (United States)

    Gorbacheva, T. T.; Ivanova, L. A.; Kikuchi, R.; Gerardo, R.

    2009-04-01

    Fast development of the industrial and urban territories during last century has led to great disturbance of natural ecosystems in a lot of regions of the world. In the Far North the risk resulted from technogenic influence involves essentially more expressed negative consequences for the nature comparing to a regions of averages and southern latitudes due to higher sensitivity of northern ecosystems. Since thirtieth years of last century industrial complexes on extraction and processing of nonferrous metals ores are functioned on Kola peninsula territory. They are powerful sources of emissions of acidifying substances and heavy metals. Long term influence of these emissions resulted in deep degradation of terrestrial ecosystems up to industrial barren arising in immediate proximity to industrial centre Monchegorsk. The most radical way of disturbed territories rehabilitation is biological remediation. In 2006-2008 innovative methods of high-quality grass cover performance was developed in local enterprise «VIPON» in Apatity. Vermiculite trademark «VIPON» is characterized by not broken structure of minerals combined with week reactance, high mechanical durability, favorable рН equal 6.5-7.0, valuable absorptive and ion exchange properties. Final product of proposed technology was rolled lawn which successfully applied for remediation of disturbed sites in urban territories as such as industrial plots with low contamination. One of abstract authors namely L.Ivanova is one of technology implementators. During 2008 the field test was performed near the smelter complex (67°51'N, 32°48'E) to estimate suitability of proposed method for site remediation in more severe conditions such as in industrial barren. The method is based on cultivation of perennial grasses using hydroponics with thermally inflated vermiculite from local deposit (Kovdor) followed by rolled lawn placement on very contaminated sites near Monchegorsk. Great advantage of rolled lawn is short

  7. An estimate of the cost of administering intravenous biological agents in Spanish day hospitals

    Directory of Open Access Journals (Sweden)

    Nolla JM

    2017-03-01

    Full Text Available Joan Miquel Nolla,1 Esperanza Martín,2 Pilar Llamas,3 Javier Manero,4 Arturo Rodríguez de la Serna,5 Manuel Francisco Fernández-Miera,6 Mercedes Rodríguez,6 José Manuel López,7 Alexandra Ivanova,8 Belén Aragón9 1Rheumatology Department, IDIBELL-Hospital Universitari de Bellvitge, Barcelona, 2Hospital Universitario de Getafe, Madrid, 3Hospital Universitario Fundación Jiménez Díaz, Madrid, 4Hospital Universitario Miguel Servet, Zaragoza, 5Hospital de la Santa Creu i Sant Pau, Barcelona, 6Hospital Universitario Marqués de Valdecilla, Santander, 7Hospital Universitario Virgen del Rocío, Sevilla, 8Max Weber Institute, Madrid, 9MSD, Madrid, Spain Objective: To estimate the unit costs of administering intravenous (IV biological agents in day hospitals (DHs in the Spanish National Health System.Patients and methods: Data were obtained from 188 patients with rheumatoid arthritis, collected from nine DHs, receiving one of the following IV therapies: infliximab (n=48, rituximab (n=38, abatacept (n=41, or tocilizumab (n=61. The fieldwork was carried out between March 2013 and March 2014. The following three groups of costs were considered: 1 structural costs, 2 material costs, and 3 staff costs. Staff costs were considered a fixed cost and were estimated according to the DH theoretical level of activity, which includes, as well as personal care of each patient, the DH general activities (complete imputation method, CIM. In addition, an alternative calculation was performed, in which the staff costs were considered a variable cost imputed according to the time spent on direct care (partial imputation method, PIM. All costs were expressed in euros for the reference year 2014.Results: The average total cost was €146.12 per infusion (standard deviation [SD] ±87.11; CIM and €29.70 per infusion (SD ±11.42; PIM. The structure-related costs per infusion varied between €2.23 and €62.35 per patient and DH; the cost of consumables oscillated

  8. Computer simulating observations of the Lunar physical libration for the Japanese Lunar project ILOM

    Science.gov (United States)

    Petrova, Natalia; Hanada, Hideo

    2010-05-01

    are calculated using the analytical theory of physical libration Petrova et al. (2008; 2009). We cannot use Newton's method for solution of the equation, because the Jacobian | | || δδfx11 δδfx12 δδf1x3-|| || δδfx2 δδfx2 δδf2x-|| J(X ) = || δf13 δf23 δ3f3-|| = 0. || δx1 δx2 δx3 || We transformed equations to the iteration form xi = φi(X). Used iteration methods have unsatisfactory convergence: inaccuracy in polar distance of 1 milliseconds of arc causes inaccuracy of 0.01arcsec in ρ and in Iσ, and 0.1 arcsec in ?. Results of our computer simulating showed It's necessary to carry out measuring of polar distances of stars in several meridians simultaneously to increase sample of stars. It's necessary to find additional links (relations) between observed parameters and libration angles to have stable mathematical methods to receive solutions for lunar rotation with high accuracy. The research was supported by the Russian-Japanese grant RFFI-JSPS 09-02-92113, (2009-2010) References: Hanada H., Noda H., Kikuchi F. et al., 2009. Different kind of observations of lunar rotation and gravity for SELENE-2. Proc of conf. Astrokazan-2009, August 19 - 26, Kazan, Russia. p. 172-175 Petrova N., Gusev A., Kawano N., Hanada H., 2008. Free librations of the two-layer Moon and the possibilities of their detection. Advances in Space Res., v 42, p. 1398-1404 Petrova N., Gusev A., Hanada H., Ivanova T., Akutina V., 2009. Application of the analytical theory of Lunar physical libration for simulating observations of stars for the future Japanese project ILOM. Proc of conf. Astrokazan-2009, August 19 - 26, Kazan, Russia. p.197 - 201.

  9. EDITORIAL: The Fifth International Workshop and Summer School on Plasma Physics

    Science.gov (United States)

    2006-04-01

    we had an unforgettable experience producing paper sheets ourselves in an old but still operational paper mill in the green enchanting spa of Duszniki Zdrój. A short intensive course in pottery handcraft was also offered to us in the Skansen. Hiking in the rocky labyrinth of Szczeliniec (please try to pronounce this name describing a magnificent cliffed hill with creviced rocks) was also a great adventure. This was followed by a ride on the serpentine Road of a Hundred Turns. And there was another event strongly supported by the local authorities. Two special tutorials on energy research and fusion for young scholars and the general public attracted nearly 200 people. The School was financially supported by the International Centre for Dense Magnetised Plasmas at IPPLM, European Commission, International Atomic Energy Agency, Vienna (Austria), the Abdus Salam International Centre for Theoretical Physics, Trieste (Italy) and the US Department of Energy. We would like to thank cordially our sponsors. Their financial support made it possible for a number of students and teachers to come to Kudowa Zdrój. We are very grateful to Dr Adam Ziembinski, the director of the spa in Kudowa, and his staff for the immense hospitality during our stay. We wish to thank Mr Czeslaw Krecichwost, the mayor of Kudowa Zdrój, for his strong support and interest in the School and help in organizing the lectures for scholars and residents of the region. And our most cordial thanks and gratitude go to Mr Ryszard Panfil for his great kindness, inexhaustible energy and organizational efficiency that helped all of us to enjoy the meeting. We thank all the participants for their contributions and we thank the reviewers of all submitted papers. Thank you for your hard work and co-operation. We are looking forward to the next school and all hope to meet again in Kudowa. Marek Rubel, Royal Institute of Technology, Sweden Irena Ivanova-Stanik, Institute of Plasma Physics and Laser Microfusion

  10. EDITORIAL: Ongoing climatic change in Northern Eurasia: justification for expedient research

    Science.gov (United States)

    Groisman, Pavel; Soja, Amber J.

    2009-12-01

    Russia A Olchev, E Novenko, O Desherevskaya, K Krasnorutskaya and J Kurbatova The effects of climate, permafrost and fire on vegetation change in Siberia in a changing climate N M Tchebakova, E Parfenova and A J Soja An image-based inventory of the spatial structure of West Siberian wetlands A Peregon, S Maksyutov and Y Yamagata Modeling of the carbon dioxide fluxes in European Russia peat bogs J Kurbatova, C Li, F Tatarinov, A Varlagin, N Shalukhina and A Olchev Feedbacks of windthrow for Norway spruce and Scots pine stands under changing climate O Panferov, C Doering, E Rauch, A Sogachev and B Ahrends Reconstruction and prediction of climate and vegetation change in the Holocene in the Altai-Sayan mountains, Central Asia N M Tchebakova, T A Blyakharchuk and E I Parfenova Simulating the effects of soil organic nitrogen and grazing on arctic tundra vegetation dynamics on the Yamal Peninsula, Russia Qin Yu, Howard Epstein and Donald Walker Possible decline of the carbon sink in the Mongolian Plateau during the 21st century Y Lu, Q Zhuang, G Zhou, A Sirin, J Melillo and D Kicklighter The frequency of forest fires in Scots pine stands of Tuva, Russia G A Ivanova, V A Ivanov, E A Kukavskaya and A J Soja Lateral extension in Sphagnum mires along the southern margin of the boreal region, Western Siberia A Peregon, M Uchida and Y Yamagata Evaluating the sensitivity of Eurasian forest biomass to climate change using a dynamic vegetation model J K Shuman and H H Shugart Studies of socioeconomic processes in Northern Eurasia Comparing patterns of ecosystem service consumption and perceptions of range management between ethnic herders in Inner Mongolia and Mongolia L Zhen, B Ochirbat, Y Lv, Y J Wei, X L Liu, J Q Chen, Z J Yao and F Li Land cover/land use change in semi-arid Inner Mongolia: 1992-2004 Ranjeet John, Jiquan Chen, Nan Lu and Burkhard Wilske Spatial and temporal patterns of greenness on the Yamal Peninsula, Russia: interactions of ecological and social factors affecting

  11. PREFACE: XVIII International Scientific Symposium in Honour of Academician M. A. Usov: Problems of Geology and Subsurface Development

    Science.gov (United States)

    2014-08-01

    presented by participants from Uzbekistan (Tashkent), Tajikistan (Dushanbe), Azerbaijan (Baku), Kazakhstan (Almaty, Semipalatinsk, Karaganda, Pavlodar), Belarus (Minsk, Gomel), Armenia (Yerevan, Gyumri), Ukraine (Kiev, Odessa, Ivano-Frankovsk, Dnepropetrovsk, Donetsk, etc.), Kyrgyzstan (Bishkek), Moldova (Chisinau). The students and young scientists from Tomsk representing Tomsk Polytechnic University, Tomsk State University, the Institute of Petroleum Geology and Geophysics (SB RAS) and other organizations and institutions took an active part in the symposium. The scientific results of the symposium were reflected in a special edition consisting of two volumes and available at (www.portal.tpu.ru/science/konf/pgon) The editorial board of the symposium and this volume of IOP Conference Series: Earth and Environmental Science consider the materials of the symposium to be interesting for researchers and young scientists of universities, research and academic institutes, academies of sciences and their branches, engineering and technical staff of ministries and government departments - for anyone who explores and develops the Earth subsurface. The editors of this volume acknowledge the administration of the Institute of Physics and its publishing house for the publication of the issue and administration of National Research Tomsk Polytechnic University, represented by the rector, professor P.S. Chubik. Executive Editor XVIII International Symposium ''Problems of Geology and Subsurface Development'' - 2014, PhD in Geology and Mineralogy, Associate Professor G.M. Ivanova

  12. ОБРАЗ ТАРАСА ШЕВЧЕНКА ЯК КОНСОЛІДУЮЧИЙ ЧИННИК ФОРМУВАННЯ УКРАЇНСЬКОЇ НАЦІОНАЛЬНОЇ ІДЕЇ У ДРУГІЙ ПОЛОВИНІ ХІХ – НА ПОЧАТКУ ХХ СТОЛІТТЯ / Taras Shevchenko figure as a unifying force in the Ukrainian national idea of the late 19th – early 20th cc.

    Directory of Open Access Journals (Sweden)

    Казакевич Ольга

    2015-12-01

    in the Ukrainian national idea of the late 19th– early 20th cc. The article is devoted to the symbolic role of the Taras Shevchenko’s representation in the Ukrainian national idea of the late 19th – early 20th cc. It is stated that Taras Shevchenko’s poetry, paintings as well as his life full of struggle for freedom, were used by the Ukrainian intellectual elite as a sign of the social and national liberation. In time when the territory of Ukraine was divided between the Russian and Habsburg empires, the Ukrainian educated class had been rather segmented. In such circumstances Taras Shevchenko even after his death played a role of the important unifying force in the Ukrainian nationalism. In the beginning of the article the scholarly views on the Taras Shevchenko’s significance are analyzed. In late 19th – early 20th cc. those scholars and publicists (V. Antonovych, E. Chykalenko, P. Zhytetsky etc. who were involved themselves in the Ukrainian national movement had stressed the great role of the Taras Shevchenko’s figure. Modern researches such as V. Sarbey, L. Ivanova, P. Magocsi, A. Wilson, A. Kapeller and others share this opinion. The author puts forward a message that Taras Shevchenko’s ideas incarnated in his works had been unifying the lower and upper classes of the Ukrainian society. Shevchenko’s poems were distributed among the lesser-educated Ukrainians through the theatrical performances and publishing activity of the Kyiv Hromada members. The role of the “Kievskaya Starina” journal where 168 articles devoted to Taras Shevchenko were published from 1882 to 1906 should be regarded. The Taras Shevchenko’s anniversary, which had been taking its place in SaintPetersburg, Kyiv, Kharkiv, Lviv, Chernivtsi and many other cities in Ukraine, Russia, Kazakhstan, Poland, Austria, Great Britain and the USA, had become the most important public demonstration of the Ukrainian patriotism. In the Russian empire it was commemorated notwithstanding

  13. Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017; Venice (Italy; October 31-November 4, 2017; Session "Neonatal Pulmonology, Neonatal Respiratory Support, Resuscitation"

    Directory of Open Access Journals (Sweden)

    --- Various Authors

    2017-10-01

    FACTANTS ON MORTALITY AND RESPIRA­TORY OUTCOMES IN PRETERM NEONATES WITH RDS: SYSTEMATIC REVIEWS AND META-ANALYSIS • L. De Martino, D. De LucaABS 18. A CLINICAL CASE OF A CHILD WITH CON­GENITAL CENTRAL HYPOVENTILATION SYN­DROME (CCHS IN THE EARLY NEONATAL PERIOD • R. Maslarska, M. Kalaydzhieva, S. Deneva, V. Konstantinova, S. Kontilska, I. Ilieva, J. Ivanova, V. Ivanova, E. Kerinova, R. Georgieva, T. TodorovABS 19. HEALTHCARE BURDEN OF BRONCHO­PUL­MO­NARY DYSPLASIA AMONG EXTREMELY PRETERM INFANTS IN THE UNITED STATES • M. Mowitz, S. Sarda, A. Mangili, R. Ayyagari, W. Gao, J. ZhaoABS 20. NCPAP PRESSURE AT INITIATION: IS HIGHER PRESSURE BETTER? • S. Bhisikar, S. Goel, S. Manerkar, J. MondkarABS 21. TRANSPORT OF HIGH-RISK NEONATES WITH RESPIRATORY FAILURE: A SINGLE CENTER COHORT ANALYSIS BASED ON THE TRANSPORT RISK INDEX OF PHYSIOLOGIC STABILITY VERSION II (TRIPS-II • M. Klemme, A. Staffler, K.M. Förster, A. Schulze, S. Herber-Jonat, J. Kappeler, A.W. FlemmerABS 22. RETROSPECTIVE AUDIT OF POSTNATAL OUTCOME OF ANTENATALLY DIAGNOSED RENAL PELVIS DILATATION • S. Vora, N. Kavalloor, T.L. Yap, P.C. Khoo, V. RajaduraiABS 23. CONTINUOUS POSITIVE AIRWAY PRESSURE IS NOT WELL TRANSMITTED DURING LESS INVASIVE SURFACTANT ADMINISTRATION: A PHYSIOLOGIC STUDY • G. Jourdain, M. De Tersant, V. Dell’Orto, G. Conti, D. De LucaABS 24. TGFβ SIGNALING IS CRITICAL FOR REGULATING A PROXIMAL DIFFERENTIATION PROGRAM AND LUNG BRANCHING MORPHOGENESIS THROUGH ACTIVATING NOTCH SIGNALING • P.N. Tsao, H.K. Chen, T.Y. Ling, W.V. CardosoABS 25. CHANGES IN EXPRESSION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF IN NEW­BORN RAT LUNGS AFTER VENTILATION • A. Remesal, E. Gutierrez, L. San Feliciano, M. Mateos, A. García-Sánchez, M. Isidoro-García, D. LudeñaABS 26. ANTENATAL GLUCOCORTICOIDS ATTENUATE CHANGES BY VENTILATION IN EXPRESSION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF IN NEWBORN RAT LUNG • M. Mateos, E. Gutierrez, L. San Feliciano, A. Remesal, M. Isidoro-García, A. Garc