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Sample records for kato chast ot

  1. Rampant Lechers, Chaste Heroes

    Heimerl, Theresia

    2017-05-01

    Full Text Available Violence is a central element of comic book screen adaptations in both Hollywood (Marvel, DC and Japan. Yet while sexual violence is openly shown in film versions of manga, coded sexualised violence dominates Western productions. Positively connoted protagonists exercise violence, but no sexualised or sexual violence, in both groups. Conversely, villains are characterised by violence and some form of sexually grounded violence, but In Western films, they are ultimately repressed lechers, and only in Japanese productions do they rampantly lose their inhibitory control. Moreover, the heroes of Japanese films are noticeably less chaste than the almost asceticcelibate romantics of Marvel and DC.

  2. Kato's chaos in set-valued discrete systems

    Gu Rongbao

    2007-01-01

    In this paper, we investigate the relationships between Kato's chaoticity of a dynamical system (X,f) and Kato's chaoticity of the set-valued discrete system (K(X),f-bar ) associated to (X,f), where X is a compact metric space and f:X->X is a continuous map. We show that Kato's chaoticity of (K(X),f-bar ) implies the Kato's chaoticity of (X,f) in general and (X,f) is chaotic in the sense of Kato if and only if (K(X),f-bar ) is Kato chaotic in w e -topology. We also show that Ruelle-Takens' chaoticity implies Kato's chaoticity for a continuous map with a fixed point from a complete metric space without isolated point into itself

  3. Kato expansion in quantum canonical perturbation theory

    Nikolaev, Andrey, E-mail: Andrey.Nikolaev@rdtex.ru [Institute of Computing for Physics and Technology, Protvino, Moscow Region, Russia and RDTeX LTD, Moscow (Russian Federation)

    2016-06-15

    This work establishes a connection between canonical perturbation series in quantum mechanics and a Kato expansion for the resolvent of the Liouville superoperator. Our approach leads to an explicit expression for a generator of a block-diagonalizing Dyson’s ordered exponential in arbitrary perturbation order. Unitary intertwining of perturbed and unperturbed averaging superprojectors allows for a description of ambiguities in the generator and block-diagonalized Hamiltonian. We compare the efficiency of the corresponding computational algorithm with the efficiencies of the Van Vleck and Magnus methods for high perturbative orders.

  4. Kato expansion in quantum canonical perturbation theory

    Nikolaev, Andrey

    2016-01-01

    This work establishes a connection between canonical perturbation series in quantum mechanics and a Kato expansion for the resolvent of the Liouville superoperator. Our approach leads to an explicit expression for a generator of a block-diagonalizing Dyson’s ordered exponential in arbitrary perturbation order. Unitary intertwining of perturbed and unperturbed averaging superprojectors allows for a description of ambiguities in the generator and block-diagonalized Hamiltonian. We compare the efficiency of the corresponding computational algorithm with the efficiencies of the Van Vleck and Magnus methods for high perturbative orders.

  5. Chaste: A test-driven approach to software development for biological modelling

    Pitt-Francis, Joe; Pathmanathan, Pras; Bernabeu, Miguel O.; Bordas, Rafel; Cooper, Jonathan; Fletcher, Alexander G.; Mirams, Gary R.; Murray, Philip; Osborne, James M.; Walter, Alex; Chapman, S. Jon; Garny, Alan; van Leeuwen, Ingeborg M.M.; Maini, Philip K.; Rodrí guez, Blanca; Waters, Sarah L.; Whiteley, Jonathan P.; Byrne, Helen M.; Gavaghan, David J.

    2009-01-01

    Chaste ('Cancer, heart and soft-tissue environment') is a software library and a set of test suites for computational simulations in the domain of biology. Current functionality has arisen from modelling in the fields of cancer, cardiac physiology

  6. On-lattice agent-based simulation of populations of cells within the open-source Chaste framework

    Figueredo, G. P.; Joshi, T. V.; Osborne, J. M.; Byrne, H. M.; Owen, M. R.

    2013-01-01

    been implemented and are available for download as part of the latest public release of Chaste (Cancer, Heart and Soft Tissue Environment; http://www.cs.ox.ac.uk/chaste/), part of the VPH Toolkit (http://toolkit.vph-noe.eu/). The environment

  7. Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications.

    Wuttke, W; Jarry, H; Christoffel, V; Spengler, B; Seidlová-Wuttke, D

    2003-05-01

    Extracts of the fruits of chaste tree (Vitex agnus castus = AC) are widely used to treat premenstrual symptoms. Double-blind placebo-controlled studies indicate that one of the most common premenstrual symptoms, i.e. premenstrual mastodynia (mastalgia) is beneficially influenced by an AC extract. In addition, numerous less rigidly controlled studies indicate that AC extracts have also beneficial effects on other psychic and somatic symptoms of the PMS. Premenstrual mastodynia is most likely due to a latent hyperprolactinemia, i.e. patients release more than physiologic amounts of prolactin in response to stressful situations and during deep sleep phases which appear to stimulate the mammary gland. Premenstrually this unphysiological prolactin release is so high that the serum prolactin levels often approach heights which are misinterpreted as prolactinomas. Since AC extracts were shown to have beneficial effects on premenstrual mastodynia serum prolactin levels in such patients were also studied in one double-blind, placebo-controlled clinical study. Serum prolactin levels were indeed reduced in the patients treated with the extract. The search for the prolactin-suppressive principle(s) yielded a number of compounds with dopaminergic properties: they bound to recombinant DA2-receptor protein and suppressed prolactin release from cultivated lactotrophs as well as in animal experiments. The search for the chemical identity of the dopaminergic compounds resulted in isolation of a number of diterpenes of which some clerodadienols were most important for the prolactin-suppressive effects. They were almost identical in their prolactin-suppressive properties than dopamine itself. Hence, it is concluded that dopaminergic compounds present in Vitex agnus castus are clinically the important compounds which improve premenstrual mastodynia and possibly also other symptoms of the premenstrual syndrome.

  8. Chaste: an open source C++ library for computational physiology and biology.

    Mirams, Gary R; Arthurs, Christopher J; Bernabeu, Miguel O; Bordas, Rafel; Cooper, Jonathan; Corrias, Alberto; Davit, Yohan; Dunn, Sara-Jane; Fletcher, Alexander G; Harvey, Daniel G; Marsh, Megan E; Osborne, James M; Pathmanathan, Pras; Pitt-Francis, Joe; Southern, James; Zemzemi, Nejib; Gavaghan, David J

    2013-01-01

    Chaste - Cancer, Heart And Soft Tissue Environment - is an open source C++ library for the computational simulation of mathematical models developed for physiology and biology. Code development has been driven by two initial applications: cardiac electrophysiology and cancer development. A large number of cardiac electrophysiology studies have been enabled and performed, including high-performance computational investigations of defibrillation on realistic human cardiac geometries. New models for the initiation and growth of tumours have been developed. In particular, cell-based simulations have provided novel insight into the role of stem cells in the colorectal crypt. Chaste is constantly evolving and is now being applied to a far wider range of problems. The code provides modules for handling common scientific computing components, such as meshes and solvers for ordinary and partial differential equations (ODEs/PDEs). Re-use of these components avoids the need for researchers to 're-invent the wheel' with each new project, accelerating the rate of progress in new applications. Chaste is developed using industrially-derived techniques, in particular test-driven development, to ensure code quality, re-use and reliability. In this article we provide examples that illustrate the types of problems Chaste can be used to solve, which can be run on a desktop computer. We highlight some scientific studies that have used or are using Chaste, and the insights they have provided. The source code, both for specific releases and the development version, is available to download under an open source Berkeley Software Distribution (BSD) licence at http://www.cs.ox.ac.uk/chaste, together with details of a mailing list and links to documentation and tutorials.

  9. Chaste: an open source C++ library for computational physiology and biology.

    Gary R Mirams

    Full Text Available Chaste - Cancer, Heart And Soft Tissue Environment - is an open source C++ library for the computational simulation of mathematical models developed for physiology and biology. Code development has been driven by two initial applications: cardiac electrophysiology and cancer development. A large number of cardiac electrophysiology studies have been enabled and performed, including high-performance computational investigations of defibrillation on realistic human cardiac geometries. New models for the initiation and growth of tumours have been developed. In particular, cell-based simulations have provided novel insight into the role of stem cells in the colorectal crypt. Chaste is constantly evolving and is now being applied to a far wider range of problems. The code provides modules for handling common scientific computing components, such as meshes and solvers for ordinary and partial differential equations (ODEs/PDEs. Re-use of these components avoids the need for researchers to 're-invent the wheel' with each new project, accelerating the rate of progress in new applications. Chaste is developed using industrially-derived techniques, in particular test-driven development, to ensure code quality, re-use and reliability. In this article we provide examples that illustrate the types of problems Chaste can be used to solve, which can be run on a desktop computer. We highlight some scientific studies that have used or are using Chaste, and the insights they have provided. The source code, both for specific releases and the development version, is available to download under an open source Berkeley Software Distribution (BSD licence at http://www.cs.ox.ac.uk/chaste, together with details of a mailing list and links to documentation and tutorials.

  10. Chaste: an open source C++ library for computational physiology and biology.

    Mirams, Gary R

    2013-03-14

    Chaste - Cancer, Heart And Soft Tissue Environment - is an open source C++ library for the computational simulation of mathematical models developed for physiology and biology. Code development has been driven by two initial applications: cardiac electrophysiology and cancer development. A large number of cardiac electrophysiology studies have been enabled and performed, including high-performance computational investigations of defibrillation on realistic human cardiac geometries. New models for the initiation and growth of tumours have been developed. In particular, cell-based simulations have provided novel insight into the role of stem cells in the colorectal crypt. Chaste is constantly evolving and is now being applied to a far wider range of problems. The code provides modules for handling common scientific computing components, such as meshes and solvers for ordinary and partial differential equations (ODEs/PDEs). Re-use of these components avoids the need for researchers to \\'re-invent the wheel\\' with each new project, accelerating the rate of progress in new applications. Chaste is developed using industrially-derived techniques, in particular test-driven development, to ensure code quality, re-use and reliability. In this article we provide examples that illustrate the types of problems Chaste can be used to solve, which can be run on a desktop computer. We highlight some scientific studies that have used or are using Chaste, and the insights they have provided. The source code, both for specific releases and the development version, is available to download under an open source Berkeley Software Distribution (BSD) licence at http://www.cs.ox.ac.uk/chaste, together with details of a mailing list and links to documentation and tutorials.

  11. Identification of New Diterpenes as Putative Marker Compounds Distinguishing Agnus Castus Fruit (Chaste Tree) from Shrub Chaste Tree Fruit (Viticis Fructus).

    Oshima, Naohiro; Masada, Sayaka; Suzuki, Ryuta; Yagi, Kanae; Matsufuji, Hiroshi; Suenaga, Emi; Takahashi, Yutaka; Yahagi, Tadahiro; Watanabe, Masato; Yahara, Shoji; Iida, Osamu; Kawahara, Nobuo; Maruyama, Takuro; Goda, Yukihiro; Hakamatsuka, Takashi

    2016-01-01

    Agnus Castus Fruit is defined in the European Pharmacopoeia as the dried ripe fruit of Vitex agnus-castus. In Europe it is used as a medicine targeting premenstrual syndrome and climacteric disorder. In Japan, Agnus Castus Fruit is becoming popular as a raw material for over-the-counter drugs and health food products, though its congenic species, Vitex rotundifolia and Vitex trifolia, have been used as Shrub Chaste Tree Fruit in traditional medicines. Therefore, it is important to discriminate these Vitex plants from the viewpoint of regulatory science. Here we tried to identify putative marker compounds that distinguish between Agnus Castus Fruit and Shrub Chaste Tree Fruit. We analyzed extracts of each crude drug by liquid chromatography-mass spectrometry, and performed differential analysis by comparison of each chromatogram to find one or more peaks characteristic of Agnus Castus Fruit. A peak was isolated and identified as an equilibrium mixture of new compounds named chastol (1) and epichastol (1a). The planar structures of 1 and 1a were determined spectroscopically. Their relative configurations were revealed by nuclear Overhauser effect spectroscopy and differential nuclear Overhauser effect-NMR data. Since avoiding contamination from closely related species is needed for the quality control of natural pharmaceuticals, this information will be valuable to establish a method for the quality control of both, Agnus Castus Fruit and Shrub Chaste Tree Fruit products. Georg Thieme Verlag KG Stuttgart · New York.

  12. Chaste: A test-driven approach to software development for biological modelling

    Pitt-Francis, Joe

    2009-12-01

    Chaste (\\'Cancer, heart and soft-tissue environment\\') is a software library and a set of test suites for computational simulations in the domain of biology. Current functionality has arisen from modelling in the fields of cancer, cardiac physiology and soft-tissue mechanics. It is released under the LGPL 2.1 licence. Chaste has been developed using agile programming methods. The project began in 2005 when it was reasoned that the modelling of a variety of physiological phenomena required both a generic mathematical modelling framework, and a generic computational/simulation framework. The Chaste project evolved from the Integrative Biology (IB) e-Science Project, an inter-institutional project aimed at developing a suitable IT infrastructure to support physiome-level computational modelling, with a primary focus on cardiac and cancer modelling. Program summary: Program title: Chaste. Catalogue identifier: AEFD_v1_0. Program summary URL: http://cpc.cs.qub.ac.uk/summaries/AEFD_v1_0.html. Program obtainable from: CPC Program Library, Queen\\'s University, Belfast, N. Ireland. Licensing provisions: LGPL 2.1. No. of lines in distributed program, including test data, etc.: 5 407 321. No. of bytes in distributed program, including test data, etc.: 42 004 554. Distribution format: tar.gz. Programming language: C++. Operating system: Unix. Has the code been vectorised or parallelized?: Yes. Parallelized using MPI. RAM:< 90   Megabytes for two of the scenarios described in Section 6 of the manuscript (Monodomain re-entry on a slab or Cylindrical crypt simulation). Up to 16 Gigabytes (distributed across processors) for full resolution bidomain cardiac simulation. Classification: 3. External routines: Boost, CodeSynthesis XSD, CxxTest, HDF5, METIS, MPI, PETSc, Triangle, Xerces. Nature of problem: Chaste may be used for solving coupled ODE and PDE systems arising from modelling biological systems. Use of Chaste in two application areas are described in this paper: cardiac

  13. Superhump Period of MASTER OT

    Garnavich, Peter; McClelland, Colin

    2013-02-01

    We observed the optical transient MASTER OT J065608.28+744455.2 (ATEL #4783) with the Vatican Advanced Technology Telescope (VATT) and VATT4K CCD camera. V-band imaging began at 2013 Feb. 5.15 (UT) and continued for 3.3 hours with a time resolution of 22 seconds.

  14. Isotope hydrology study of Kato Nevrokopi of Dramas

    Leontiadis, I.L.; Payne, B.R.; Letsios, A.; Papagianni, N.; Kakarelis, D.; Chadjiagorakis, D.

    1984-01-01

    The isotopic composition of the water was used in order to define the mechanism of recharge of the high plateau of Kato Nevrokopi of Dramas. The results of this study indicate that there are two main sources of recharge to groundwater. One is infiltration of water from the network of irrigation canals which carry water from the Vathitopos stream. The other source of recharge originates in the mountains to the east of the plain. Infiltration from the Nevrokopi stream does occur, but is believed to be minor in this part of the plain. Recharge by infiltration of local precipitation is considered to be minor in comparison with the two main sources of recharge. An underground barrier prevents draining of the groundwater through the sinkhole, resulting in a very big reservoir under the whole central and southern parts of the high plateau. The exploitation of the groundwater of this reservoir very probably offers a low-cost solution to satisfy all needs of the area for irrigation water. (author)

  15. OT-Combiners Via Secure Computation

    Harnik, Danny; Ishai, Yuval; Kushilevitz, Eyal

    2008-01-01

    of faulty candidates (t = Ω(n)). Previous OT-combiners required either ω(n) or poly(k) calls to the n candidates, where k is a security parameter, and produced only a single secure OT. We demonstrate the usefulness of the latter result by presenting several applications that are of independent interest......An OT-combiner implements a secure oblivious transfer (OT) protocol using oracle access to n OT-candidates of which at most t may be faulty. We introduce a new general approach for combining OTs by making a simple and modular use of protocols for secure computation. Specifically, we obtain an OT......, strengthen the security, and improve the efficiency of previous OT-combiners. In particular, we obtain the first constant-rate OT-combiners in which the number of secure OTs being produced is a constant fraction of the total number of calls to the OT-candidates, while still tolerating a constant fraction...

  16. Comparing concentration methods: parasitrap® versus Kato-Katz for ...

    Comparing concentration methods: parasitrap® versus Kato-Katz for studying the prevalence of Helminths in Bengo province, Angola. Clara Mirante, Isabel Clemente, Graciette Zambu, Catarina Alexandre, Teresa Ganga, Carlos Mayer, Miguel Brito ...

  17. 75 FR 51169 - OTS Minority Depository Institutions Advisory Committee

    2010-08-18

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision [Docket ID: OTS-2010-0026] OTS Minority... (OTS). ACTION: Notice. SUMMARY: The Charter for the OTS Minority Depository Institutions Advisory... of the Treasury to announce the renewal of the OTS Minority Depository Institutions Advisory...

  18. LATERAL SURVIVAL: AN OT ACCOUNT

    Moira Yip

    2004-12-01

    Full Text Available When laterals are the targets of phonological processes, laterality may or may not survive. In a fixed feature geometry, [lateral] should be lost if its superordinate node is eliminated by either the spreading of a neighbouring node, or by coda neutralization. So if [lateral] is under Coronal (Blevins 1994, it should be lost under Place assimilation, and if [lateral] is under Sonorant Voicing (Rice & Avery 1991 it should be lost by rules that spread voicing. Yet in some languages lateral survives such spreading intact. Facts like these argue against a universal attachment of [lateral] under either Coronal or Sonorant Voicing, and in favour of an account in terms of markedness constraints on feature-co-occurrence (Padgett 2000. The core of an OT account is that IFIDENTLAT is ranked above whatever causes neutralization, such as SHARE-F or *CODAF. laterality will survive. If these rankings are reversed, we derive languages in which laterality is lost. The other significant factor is markedness. High-ranked feature co-occurrence constraints like *LATDORSAL can block spreading from affecting laterals at all.

  19. Oscillation estimates relative to p-homogeneous forms and Kato measures data

    Marco Biroli

    2006-11-01

    Full Text Available We state pointwise estimate for the positive subsolutions associated to a p-homogeneous form and nonnegative Radon measures data. As a by-product we establish an oscillation’s estimate for the solutions relative to Kato measures data.

  20. Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry).

    Liu, J; Burdette, J E; Sun, Y; Deng, S; Schlecht, S M; Zheng, W; Nikolic, D; Mahady, G; van Breemen, R B; Fong, H H S; Pezzuto, J M; Bolton, J L; Farnsworth, N R

    2004-01-01

    A methanol extract of chaste-tree berry (Vitex agnus-castus L.) was tested for its ability to displace radiolabeled estradiol from the binding site of estrogen receptors alpha (ERalpha) and beta (ERbeta). The extract at 46 +/- 3 microg/ml displaced 50% of estradiol from ERalpha and 64 +/- 4 microg/ml from ERbeta. Treatment of the ER+ hormone-dependent T47D:A18 breast cancer cell line with the extract induced up-regulation of ERbeta mRNA. Progesterone receptor (PR) mRNA was upregulated in the Ishikawa endometrial cancer cell line. However, chaste-tree berry extract did not induce estrogen-dependent alkaline phosphatase (AP) activity in Ishikawa cells. Bioassay-guided isolation, utilizing ER binding as a monitor, resulted in the isolation of linoleic acid as one possible estrogenic component of the extract. The use of pulsed ultrafiltration liquid chromatography-mass spectrometry, which is an affinity-based screening technique, also identified linoleic acid as an ER ligand based on its selective affinity, molecular weight, and retention time. Linoleic acid also stimulated mRNA ERbeta expression in T47D:A18 cells, PR expression in Ishikawa cells, but not AP activity in Ishikawa cells. These data suggest that linoleic acid from the fruits of Vitex agnus-castus can bind to estrogen receptors and induce certain estrogen inducible genes.

  1. Mini-FLOTAC and Kato-Katz: helminth eggs watching on the shore of Lake Victoria.

    Barda, Beatrice; Zepherine, Henry; Rinaldi, Laura; Cringoli, Giuseppe; Burioni, Roberto; Clementi, Massimo; Albonico, Marco

    2013-07-31

    One of the challenges for monitoring helminth control programmes based on preventive chemotherapy is the lack of a copro-parasitological gold-standard method that combines good sensitivity with quantitative performance, low cost, and easy-to-learn technique.The aim of our study was to evaluate and compare, the WHO recommended quantitative diagnostic technique (Kato-Katz) and the Mini-FLOTAC. Mini-FLOTAC is an innovative method based on floatation of helminths eggs with two different solutions (FS2 and FS7) using a close system (Fill-FLOTAC) with 5% fixative. Kato-Katz was performed following WHO recommendation. The study was carried out in a rural part of Tanzania, close to Lake Victoria, where the laboratory facilities are fairly scarce, and the basic technique used in the local laboratory (direct smear) was taken as reference standard. 201 children were screened for intestinal helminths and 91% of them were found to be positive. The agreement among the three techniques was calculated with k Cohen coefficient and was fairly good (k = 0.4), although the Mini-FLOTAC results were more sensitive for hookworm (98%) with FS2, and for S.mansoni (90%) with FS7 followed by Kato-Katz (91% and 60% respectively) and direct smear (30% and 10% respectively). A good agreement was found between Mini-FLOTAC and Kato-Katz (k = 0.81) with FS7 (k = 0.76) for hookworm diagnosis and a fairly good one for S.mansoni diagnosis (k = 0.5). For both infections we had a poor agreement between the two quantitative techniques and the direct smear (kMcMaster) and in different settings where other soil-transmitted helminths are also endemic.

  2. On-lattice agent-based simulation of populations of cells within the open-source Chaste framework.

    Figueredo, Grazziela P; Joshi, Tanvi V; Osborne, James M; Byrne, Helen M; Owen, Markus R

    2013-04-06

    Over the years, agent-based models have been developed that combine cell division and reinforced random walks of cells on a regular lattice, reaction-diffusion equations for nutrients and growth factors; and ordinary differential equations for the subcellular networks regulating the cell cycle. When linked to a vascular layer, this multiple scale model framework has been applied to tumour growth and therapy. Here, we report on the creation of an agent-based multi-scale environment amalgamating the characteristics of these models within a Virtual Physiological Human (VPH) Exemplar Project. This project enables reuse, integration, expansion and sharing of the model and relevant data. The agent-based and reaction-diffusion parts of the multi-scale model have been implemented and are available for download as part of the latest public release of Chaste (Cancer, Heart and Soft Tissue Environment; http://www.cs.ox.ac.uk/chaste/), part of the VPH Toolkit (http://toolkit.vph-noe.eu/). The environment functionalities are verified against the original models, in addition to extra validation of all aspects of the code. In this work, we present the details of the implementation of the agent-based environment, including the system description, the conceptual model, the development of the simulation model and the processes of verification and validation of the simulation results. We explore the potential use of the environment by presenting exemplar applications of the 'what if' scenarios that can easily be studied in the environment. These examples relate to tumour growth, cellular competition for resources and tumour responses to hypoxia (low oxygen levels). We conclude our work by summarizing the future steps for the expansion of the current system.

  3. On-lattice agent-based simulation of populations of cells within the open-source Chaste framework

    Figueredo, G. P.

    2013-02-21

    Over the years, agent-based models have been developed that combine cell division and reinforced random walks of cells on a regular lattice, reaction-diffusion equations for nutrients and growth factors; and ordinary differential equations for the subcellular networks regulating the cell cycle. When linked to a vascular layer, this multiple scale model framework has been applied to tumour growth and therapy. Here, we report on the creation of an agent-based multi-scale environment amalgamating the characteristics of these models within a Virtual Physiological Human (VPH) Exemplar Project. This project enables reuse, integration, expansion and sharing of the model and relevant data. The agent-based and reaction-diffusion parts of the multi-scale model have been implemented and are available for download as part of the latest public release of Chaste (Cancer, Heart and Soft Tissue Environment; http://www.cs.ox.ac.uk/chaste/), part of the VPH Toolkit (http://toolkit.vph-noe.eu/). The environment functionalities are verified against the original models, in addition to extra validation of all aspects of the code. In this work, we present the details of the implementation of the agent-based environment, including the system description, the conceptual model, the development of the simulation model and the processes of verification and validation of the simulation results. We explore the potential use of the environment by presenting exemplar applications of the \\'what if\\' scenarios that can easily be studied in the environment. These examples relate to tumour growth, cellular competition for resources and tumour responses to hypoxia (low oxygen levels). We conclude our work by summarizing the future steps for the expansion of the current system.

  4. Comparative cost assessment of the Kato-Katz and FLOTAC techniques for soil-transmitted helminth diagnosis in epidemiological surveys

    Speich Benjamin

    2010-08-01

    Full Text Available Abstract Background The Kato-Katz technique is widely used for the diagnosis of soil-transmitted helminthiasis in epidemiological surveys and is believed to be an inexpensive method. The FLOTAC technique shows a higher sensitivity for the diagnosis of light-intensity soil-transmitted helminth infections but is reported to be more complex and expensive. We assessed the costs related to the collection, processing and microscopic examination of stool samples using the Kato-Katz and FLOTAC techniques in an epidemiological survey carried out in Zanzibar, Tanzania. Methods We measured the time for the collection of a single stool specimen in the field, transfer to a laboratory, preparation and microscopic examination using standard protocols for the Kato-Katz and FLOTAC techniques. Salaries of health workers, life expectancy and asset costs of materials, and infrastructure costs were determined. The average cost for a single or duplicate Kato-Katz thick smears and the FLOTAC dual or double technique were calculated. Results The average time needed to collect a stool specimen and perform a single or duplicate Kato-Katz thick smears or the FLOTAC dual or double technique was 20 min and 34 sec (20:34 min, 27:21 min, 28:14 min and 36:44 min, respectively. The total costs for a single and duplicate Kato-Katz thick smears were US$ 1.73 and US$ 2.06, respectively, and for the FLOTAC double and dual technique US$ 2.35 and US$ 2.83, respectively. Salaries impacted most on the total costs of either method. Conclusions The time and cost for soil-transmitted helminth diagnosis using either the Kato-Katz or FLOTAC method in epidemiological surveys are considerable. Our results can help to guide healthcare decision makers and scientists in budget planning and funding for epidemiological surveys, anthelminthic drug efficacy trials and monitoring of control interventions.

  5. Trotter-Kato product formula and fractional powers of self-adjoint generators

    Ichinose, I; Zagrebnov, Z

    2002-01-01

    Let $A$ and $B$ be non-negative self-adjoint operators in a Hilbert space such that their densely defined form sum $H = A \\stackrel{\\cdot}{+} B$ obeys $\\dom(H^\\ga) \\subseteq \\dom(A^\\ga) \\cap \\dom(B^\\ga)$ for some $\\ga \\in (1/2,1)$. It is proved that if, in addition, $A$ and $B$ satisfy $\\dom(A^{1/2}) \\subseteq \\dom(B^{1/2})$, then the symmetric and non-symmetric Trotter-Kato product formula converges in the operator norm: % % \\bed \\ba{c} \\left\\|\\left(e^{-tB/2n}e^{-tA/n}e^{-tB/2n}\\right)^n - e^{-tH}\\right\\| = O(n^{-(2\\ga-1)}), \\\\[2mm] \\left\\|\\left(e^{-tA/n}e^{-tB/n}\\right)^n - e^{-tH}\\right\\| = O(n^{-(2\\ga-1)}) \\ea \\eed % % uniformly in $t \\in [0,T]$, $0 < T < \\infty$, as $n \\to \\infty$, both with the same optimal error bound. The same is valid if one replaces the exponential function in the product by functions of the Kato class, that is, by real-valued Borel measurable functions $f(\\cdot)$ defined on the non-negative real axis obeying $0 \\le f(x) \\le 1$, $f(0) = 1$ and $f'(+0) = -1$, with some addition...

  6. Investigation of the spatial generalization of Kato's theorem by a variational density-functional approach

    Csavinszky, P.

    1990-01-01

    In a recent work, March has considered the quantum-mechanical system of an arbitrary number of closed electronic shells around an atomic nucleus of charge Z a e. March has assumed that the shells are filled by noninteracting electrons, moving in the bare Coulomb potential energy of V(r) = -Z a e 2 /r. In this framework, the basic quantity is the total electron (number) density ρ(r), built by summing the (number) density ρ n (r) of the nth closed electronic shell over the principal quantum number n. March has shown that Kato's theorem, (∂ρ(r)/∂r) r=0 = -(2Z a /a 0 )ρ (r = 0), with a 0 = ℎ 2 /me 2 , is amenable to a spatially dependent generalization that can be expressed by ∂ρ(r)/∂r = -(2Z a /a 0 )ρ s (r), where ρ s (r) is the s-state contribution from the n closed electronic shells to ρ(r). The present work investigates the spatially dependent generalization of Kato's theorem for the Ne atom by making use of a variational density-functional approach and adopting several expressions for the kinetic-energy functional of the electrons. The intriguing question of identifying the best kinetic-energy functional is raised and discussed

  7. Quality evaluation of medicinal products and health foods containing chaste berry (Vitex agnus-castus) in Japanese, European and American markets.

    Fukahori, Masahiro; Kobayashi, Shojiro; Naraki, Yoko; Sasaki, Takahiro; Oka, Hideki; Seki, Masaharu; Masada-Atsumi, Sayaka; Hakamatsuka, Takashi; Goda, Yukihiro

    2014-01-01

    The aim of present study was to evaluate the qualities of chaste berry (fruit of Vitex agnus-castus L.) preparations using HPLC fingerprint analysis. Seven medicinal products 1 from Japan and 6 from Europe, and 17 health foods, 6 from Japan and 11 from the United States were analyzed. HPLC profile and 26 authentic peaks were compared medicinal products and health foods. Whereas medicinal products had similar HPLC profiles, health foods had various profiles and each peak was also greatly different. The measured amounts of two markers in 5 traditional medicinal products, agnuside and casticin specified in the European Pharmacopoeia (EP), the U.S. Pharmacopoeia (USP) or the WHO monographs of chaste berry, were much lower than those in 2 medicinal products defined as "well-established use" by the European Medicines Agency. The amounts of two markers for 17 health foods differed in a great deal from 14-5054% and 3-1272%, respectively. Furthermore the amount ratios of two markers, agnuside/casticin, in about half of the health foods were remarkably larger than the standard crude drug and the ratios were closer to one of the related Chinese herbs, Vitex negundo L. It is concluded that a combination of HPLC fingerprints and the amount ratios of the marker compounds of chaste berry preparations serves as a useful tool to evaluate the qualities of these preparations.

  8. Estudo comparativo dos métodos coprológicos de Lutz, Kato-Katz e Faust modificado A comparative study of the coprologic methods of Lutz, Kato-Katz and the Faust modified

    Adelú Chaves

    1979-12-01

    Full Text Available Foram estudados, comparativamente, em 500 pacientes, os métodos de exames de fezes de Lutz, Faust modificado e Kato-Katz para o diagnóstico parasitológico de fezes. O método de Kato-Katz proporcionou maiores índices de positividade do que as outras duas técnicas no diagnóstico de ancilostomideos, T. trichiurus e S. mansoni. Nenhuma diferença foi observada quanto ao diagnóstico de A. lumbricoides. Para o diagnóstico das protozooses não houve diferença significativa entre os métodos de Faust modificado e de Lutz. Baseado nos dados obtidos, eficiência, simplicidade e rapidez de execução recomenda-se a associação dos métodos de Kato-Katz e Faust modificado na rotina de diagnóstico parasitológico de fezes.A comparative study was of the Lutz, Faust (modified, and Kato-Katz stool examination methods for parasitological diagnosis using 500 patients. The Kato-Katz method provided higher rates of positivity than the other two techniques in the diagnosis of Ancylostomidae, T. trichiurus, and S. mansoni. No differences were observed in the diagnosis of A. lumbicoides. Nor was a statistically significant difference observed in the diagnosis of protozoosis when using the Lutz and modified Faust methods. The data obtained led to a recommendation for an association of Kato-Katz and modified Faust methods for routine parasitological diagnosis due to Us simplicity, rapidity, and efficiency.

  9. Comparing concentration methods: parasitrap® versus Kato-Katz for studying the prevalence of Helminths in Bengo province, Angola.

    Mirante, Clara; Clemente, Isabel; Zambu, Graciette; Alexandre, Catarina; Ganga, Teresa; Mayer, Carlos; Brito, Miguel

    2016-09-01

    Helminth intestinal parasitoses are responsible for high levels of child mortality and morbidity. Hence, the capacity to diagnose these parasitoses and consequently ensure due treatment represents a factor of great importance. The main objective of this study involves comparing two methods of concentration, parasitrap and Kato-Katz, for the diagnosis of intestinal parasitoses in faecal samples. Sample processing made recourse to two different concentration methods: the commercial parasitrap® method and the Kato-Katz method. We correspondingly collected a total of 610 stool samples from pre-school and school age children. The results demonstrate the incidence of helminth parasites in 32.8% or 32.3% of the sample collected depending on whether the concentration method applied was either the parasitrap method or the Kato-Katz method. We detected a relatively high percentage of samples testing positive for two or more species of helminth parasites. We would highlight that in searching for larvae the Kato-Katz method does not prove as appropriate as the parasitrap method. Both techniques prove easily applicable even in field working conditions and returning mutually agreeing results. This study concludes in favour of the need for deworming programs and greater public awareness among the rural populations of Angola.

  10. Fabrication of PEDOT-OTS-patterned ITO substrates

    Herzer, N.; Wienk, M.M.; Schmit, P.; Spoelstra, A.B.; Hendriks, C.E.; Oosterhout, S.D.; Höppener, S.; Schubert, U.S.

    2010-01-01

    The fabrication of a poly(3,4-ethylenedioxythiophene) (PEDOT) pattern is demonstrated. As template, an n-octadecyltrichlorosilane (OTS) monolayer self-assembled on indium tin oxide (ITO) was structured by UV–ozone photolithography, resulting in an ITO–OTS patterned surface. The conducting properties

  11. 12 CFR 510.5 - Release of unpublished OTS information.

    2010-01-01

    ... ORGANIZATIONAL REGULATIONS § 510.5 Release of unpublished OTS information. (a) Scope. (1) This section applies to... their official capacities. Examples of unpublished information include: (i) Information in the memory of...

  12. Changeover Inference: Estimating the Relationship Between DT and OT Data

    Dippery, Kevin

    1997-01-01

    ... which has undergone developmental testing. Using a re-sampling method called the Bootstrap, the sampling variance and standard error of the changeover factor are calculated, as are confidence intervals for the OT failure rate of a new system...

  13. 12 CFR 500.10 - The OTS or The Office.

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false The OTS or The Office. 500.10 Section 500.10 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY AGENCY ORGANIZATION AND FUNCTIONS General Organization § 500.10 The OTS or The Office. The Office of Thrift Supervision (referred to as “OTS” or “Office”) is an office of the...

  14. De Sébastien Roch à L’agneau chaste ou de la construction à la déconstruction de la matrice romanesque de la pédophilie

    Szczur Przemysław

    2015-12-01

    Full Text Available L’obiettivo del presente articolo è di paragonare l’immagine della pedofilia in due romanzi : Sébastien Roch di Octave Mirbeau e L’agneau chaste di Franck Varjac. Mentre il primo ha contribuito a costruire la matrice romanzesca della pedofilia, il secondo prova a decostruirla.

  15. Kato-Katz and Lumbreras rapid sedimentation test to evaluate helminth prevalence in the setting of a school-based deworming program

    Lopez, Martha; Morales, Maria Luisa; Konana, Monisha; Hoyer, Paige; Pineda-Reyes, Roberto; White, Arthur Clinton; Garcia, Hector Hugo; Lescano, Andres Guillermo; Gotuzzo, Eduardo; Cabada, Miguel Mauricio

    2016-01-01

    The sensitivity of the Kato-Katz test is suboptimal for the evaluation of intestinal helminth prevalence. Moreover, during mass deworming, as helminth egg burden decreases, the sensitivity is likely to decrease. The Lumbreras rapid sedimentation (Lumbreras) is a low-cost non-quantitative test, but may provide useful information in low burden areas. We compared the prevalence of intestinal helminth infections assessed by the Kato-Katz and the Lumbreras rapid sedimentation test on 3 stool speci...

  16. Castas estrelas! Chaste stars

    Regina Andrade

    1999-01-01

    Full Text Available Este trabalho é uma parte da pesquisa Processos de Adaptações Criativas - Cinema Literário e Psicanálise, cujo objetivo principal é a análise específica da linguagem e das transformações sofridas pelos textos literários quando da passagem para textos fílmicos. Apresento como exemplo o filme Quincas Borba (dirigido por Roberto Santos, baseado no livro homônimo de Machado de Assis.This paper is the abridgment of the research Processos de Adaptações Criativas - Cinema Literário e Psicanálise (Creative Adaptation Processes - Literary Cinema and Psychoanalysis, which main goal is the specific analysis of language as well as of the transformations undergone by literary texts in their translation to filmic texts. I present as an example the movie Quincas Borba (directed by Roberto Santos, based on the homonymous book by Machado de Assis.

  17. 12 CFR 502.50 - What fees does OTS charge?

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What fees does OTS charge? 502.50 Section 502.50 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES... consolidated with a savings association on the Consolidated Statement of Condition of the Thrift Financial...

  18. Recent optical activity of the blazar OT 355

    Bachev, R.; Kurtenkov, A.; Nikolov, Y.; Spassov, B.; Boeva, S.; Latev, G.; Dimitrova, R. V. Munoz

    2017-06-01

    The Flat Spectrum Radio Quasar OT 355 (also known as 7C 173240.70+385949.00, z=0.975) was typically observed to be in the optical between 16th and 21th magnitude (CRTS, http://nesssi.cacr.caltech.edu/catalina/20011332/113321380764100137p.html).

  19. 12 CFR 563b.115 - How will OTS review my business plan?

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How will OTS review my business plan? 563b.115... business plan? (a) OTS will review your business plan to determine that it demonstrates a safe and sound... will be determinative. OTS will review every case on its merits. (b) You must file your business plan...

  20. A categorization of customer concerns for an OT front-end of innovation process in an IT/OT convergence context

    Bonnetto , Emilie; YANNOU , Bernard; Bertoluci , Gwenola; Boly , Vincent; Alvarez , Jorge

    2016-01-01

    International audience; Operational Technologies (OT) are designed to monitor and control plants. OT are increasingly mixed with Information Technologies (IT) in global solutions. A conventional customer inquiry is no more sufficient to get enough data about Customer Concerns (CC). Indeed, an IT OT solution is the nervous system of a company; it intertwines people processes and functions. For specification step, one must now capture negative perceptions in the interrelationships with other ac...

  1. OT - Education for the health services of the future

    Hansen, Bodil Winther; Sørensen, Annette; Hove, Anne

    OT - Education for the health services of the future This presentation offers knowledge about which qualifications the health services and OT practice in general demand from Occupational Therapists. The study was developed in a wider context of the constant reflection within higher education...... as a result of the rapid pace of change in society. The Faculty of Occupational Therapy in Copenhagen wanted to enable the graduates in the best possible way to meet the employers’ demands as to qualifications. Furthermore, the aim was to develop and guarantee the quality of the educations offered...... by University College Oeresund. To express the level of education to be achieved in terms of competences and learning outcome, the study was inspired by the tuning process of educational structures in Europe, which is part of the Bologna process to integrate higher education area in Europe. The study is based...

  2. Optimization of OT-MACH Filter Generation for Target Recognition

    Johnson, Oliver C.; Edens, Weston; Lu, Thomas T.; Chao, Tien-Hsin

    2009-01-01

    An automatic Optimum Trade-off Maximum Average Correlation Height (OT-MACH) filter generator for use in a gray-scale optical correlator (GOC) has been developed for improved target detection at JPL. While the OT-MACH filter has been shown to be an optimal filter for target detection, actually solving for the optimum is too computationally intensive for multiple targets. Instead, an adaptive step gradient descent method was tested to iteratively optimize the three OT-MACH parameters, alpha, beta, and gamma. The feedback for the gradient descent method was a composite of the performance measures, correlation peak height and peak to side lobe ratio. The automated method generated and tested multiple filters in order to approach the optimal filter quicker and more reliably than the current manual method. Initial usage and testing has shown preliminary success at finding an approximation of the optimal filter, in terms of alpha, beta, gamma values. This corresponded to a substantial improvement in detection performance where the true positive rate increased for the same average false positives per image.

  3. A técnica de Kato para o diagnóstico coprológico de infecções parasitárias

    Jairo Gonçalves Molina

    1971-02-01

    Full Text Available Empregando-se 76 espécimenis de fezes examinados velo método de Kato modificiado por Martin e Beaver (4, fêz-se a comparação com a técnica da sedimentação pelo método de Hoffman, Pons e Janer. Excetuando o diagnóstico das infecções pelo T. trichurus, nas quais houve evidentes vantagens do método de Kato, não se pode confirmar a superioridade do método de Kato, pelo menos nas condições do laboratório clínico normal. O autor frisa porém, que por falta de espécimens adequados não foi possível testar o método nas infecções pelo S. mansoni, campo que se ressente da falta de técnicas adequadas para o diagnóstico de infecções discretas e no qual se antecipam maiores virtudes do método de Kato.

  4. Determination and Identification of a Specific Marker Compound for Discriminating Shrub Chaste Tree Fruit from Agnus Castus Fruit Based on LC/MS Metabolic Analysis.

    Yahagi, Tadahiro; Masada, Sayaka; Oshima, Naohiro; Suzuki, Ryuta; Matsufuji, Hiroshi; Takahashi, Yutaka; Watanabe, Masato; Yahara, Shoji; Iida, Osamu; Kawahara, Nobuo; Maruyama, Takuro; Goda, Yukihiro; Hakamatsuka, Takashi

    2016-01-01

    Shrub Chaste Tree Fruit (SCTF) is defined as the fruits of Vitex rotundifolia L. f. and V. trifolia L. and has been used as a component of some traditional Japanese medicines (Kampo formulations). Agnus Castus Fruit (ACF) is defined as the dried ripe fruits of V. agnus-castus L.; it is used in traditional European medicines, but is becoming popular in Japan as both an over-the-counter drug and as an ingredient in health foods for treating premenstrual syndrome (PMS). To ensure the efficacy and safety of both SCTF and ACF products, it is important to precisely authenticate their botanical origins and to clearly distinguish between SCTF and ACF. Therefore, we tried to identify SCTF-specific marker compounds based on LC/MS metabolic analysis. The multivariate analysis of LC/MS data from SCTF and ACF samples furnished candidate marker compounds of SCTF. An SCTF-specific marker was isolated from SCTF crude drugs and identified as 3-O-trans-feruloyl tormentic acid on the basis of spectroscopic data from NMR and MS. Since avoiding contamination from closely related species is a significant requirement for pharmaceuticals of natural origin, this information will be valuable for the quality control of both SCTF and ACF products from the viewpoint of regulatory science.

  5. MASTER-SAAO: contradictory SN and flaring OT

    Balanutsa, P.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Kornilov, V.; Gress, O.; Pogrosheva, T.; Shumkov, V.; Vladimirov, V.; Vlasenko, D.; Kuvshinov, D.; Gabovich, A.

    2017-07-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 03h 42m 50.70s , -01d 52m 28s.7 on 2017-07-01.1753UT with unfiltered (6 images), that contradicts to Ia type detected in ATEL #10240 , ATEL #10225 for ATLAS17dcl ( http://www.supernova.thistlethwaites.com/sn2017/sndate.html ). It is in 8.4"W,20"S of PGC135685 with Btc=15.13, Vgsr=2773 http://leda.univ-lyon1.fr/ledacat.cgi?PGC135685 Spectral observations are required.

  6. Evaluation and selection of CASE tool for SMART OTS development

    Park, K. O; Seo, S. M.; Seo, Y. S.; Koo, I. S.; Jang, M. H.

    1999-01-01

    CASE(Computer-Aided Software Engineering) tool is a software that aids in software engineering activities such as requirement analysis, design, testing, configuration management, and project management. The evaluation and selection of commercial CASE tools for the specific software development project is not a easy work because the technical ability of an evaluator and the maturity of a software development organization are required. In this paper, we discuss selection strategies, characteristic survey, evaluation criteria, and the result of CASE tool selection for the development of SMART(System-integrated Modular Advanced ReacTor) OTS(Operator Training Simulator)

  7. Coastline changes in relation to longshore sediment transport and human impact, along the shoreline of Kato Achaia (NW Peloponnese, Greece

    S. POULOS

    2001-06-01

    Full Text Available Coastal configuration depends upon the equilibrium between available sediment budget and prevailing nearshore wave and current conditions. Human activities often disturb this natural equilibrium by altering the sources of beach material and littoral drift pattern. In the coastal zone of NW Peloponnese, an essentially tideless environment, the oblique approach of wind-induced waves implies an overall longshore drift from east to west. On an annual basis, the potential longshore sediment transport rates at the different sections of the study area (Kato Achaia is estimated to vary between 0.02 10-3 m3/s and 5 103 m3/s and to fluctuate seasonally. The construction of a port and the extraction of aggregates from the R. Peiros have changed significantly the pattern of sediment transport inducing dramatic changes on coastline configuration; thus, the part of the coastline west to the port had retreated as much as 70 m eliminating a touristic beach, while the entrance of the port was silted inhibiting navigation. Coastal engineering measures, such as modification of port-breakwaters and construction of groins have had only minimal contribution in beach recovery. Hence, coastal management plans should consider this dynamic equilibrium and protect the natural coastal system from the arbitrary human activities.

  8. Estudo sobre o diagnóstico da giardíase por meio do método Kato-Katz

    Vera Lucia Pagliusi Castilho

    1983-06-01

    Full Text Available Foi verificado que é possível diagnosticar a giardíase através de exame de fezes realizado pelo método de Kato-Katz, hoje bastante utilizado no Brasil. Todavia, para reconhecimento da protozoose em questão, a eficácia do processo da centrífugo-fiutuação em sulfato de zinco mostrou-se maior. As sensibilidades das técnicas de Kato-Katz e da sedimentação espontânea em água foram equiparáveis, afigurando-se mais produtivas, a propósito do emprego da primeira, as análises efetuadas imediatamente ou após 24 horas em relação à ocasião do preparo.

  9. Kato-Katz and Lumbreras rapid sedimentation test to evaluate helminth prevalence in the setting of a school-based deworming program

    Lopez, Martha; Morales, Maria Luisa; Konana, Monisha; Hoyer, Paige; Pineda-Reyes, Roberto; White, Arthur Clinton; Garcia, Hector Hugo; Lescano, Andres Guillermo; Gotuzzo, Eduardo; Cabada, Miguel Mauricio

    2016-01-01

    The sensitivity of the Kato-Katz test is suboptimal for the evaluation of intestinal helminth prevalence. Moreover, during mass deworming, as helminth egg burden decreases, the sensitivity is likely to decrease. The Lumbreras rapid sedimentation (Lumbreras) is a low-cost non-quantitative test, but may provide useful information in low burden areas. We compared the prevalence of intestinal helminth infections assessed by the Kato-Katz and the Lumbreras rapid sedimentation test on 3 stool specimens from each of 1083 children. The sensitivities were compared using the McNemar paired test. Using the combined outcome of the 3 different stool tests as the standard, Kato-Katz had lower sensitivity than Lumbreras rapid sedimentation tests for Ascaris lumbricoides (85.1% vs. 95.1%, p = 0.03), Hymenolepis nana (77.7% vs. 97.9%, p Lumbreras rapid sedimentation tests enables the detection of more intestinal helminths infections in post-deworming low prevalence areas. PMID:27376503

  10. 12 CFR 502.55 - Where can I find OTS's fee schedule?

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Where can I find OTS's fee schedule? 502.55 Section 502.55 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND... fees in a Thrift Bulletin. OTS will publish these fees at least 30 days before they are effective. ...

  11. 12 CFR 502.60 - When will OTS adjust, add, waive, or eliminate a fee?

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false When will OTS adjust, add, waive, or eliminate a fee? 502.60 Section 502.60 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES Fees § 502.60 When will OTS adjust, add, waive, or eliminate a fee? Under...

  12. 12 CFR 516.10 - How does OTS compute time periods under this part?

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How does OTS compute time periods under this part? 516.10 Section 516.10 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES § 516.10 How does OTS compute time periods under this part? In computing...

  13. 12 CFR 516.170 - When will OTS conduct a meeting on an application?

    2010-01-01

    ... application, or otherwise determines that a meeting will benefit the decision-making process. OTS may limit... inform the applicant and all commenters requesting a meeting of its decision to grant or deny a meeting request, or of its decision to conduct a meeting on its own initiative. (c) If OTS decides to conduct a...

  14. 12 CFR 563.146 - Will the OTS permit my capital distribution?

    2010-01-01

    ... under 12 U.S.C. 1831o(d)(1)(B). (b) Your proposed capital distribution raises safety or soundness... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Will the OTS permit my capital distribution... SAVINGS ASSOCIATIONS-OPERATIONS Capital Distributions § 563.146 Will the OTS permit my capital...

  15. Estimating sensitivity of the Kato-Katz technique for the diagnosis of Schistosoma mansoni and hookworm in relation to infection intensity.

    Oliver Bärenbold

    2017-10-01

    Full Text Available The Kato-Katz technique is the most widely used diagnostic method in epidemiologic surveys and drug efficacy trials pertaining to intestinal schistosomiasis and soil-transmitted helminthiasis. However, the sensitivity of the technique is low, particularly for the detection of light-intensity helminth infections. Examination of multiple stool samples reduces the diagnostic error; yet, most studies rely on a single Kato-Katz thick smear, thus underestimating infection prevalence. We present a model which estimates the sensitivity of the Kato-Katz technique in Schistosoma mansoni and hookworm, as a function of infection intensity for repeated stool sampling and provide estimates of the age-dependent 'true' prevalence. We find that the sensitivity for S. mansoni diagnosis is dominated by missed light infections, which have a low probability to be diagnosed correctly even through repeated sampling. The overall sensitivity strongly depends on the mean infection intensity. In particular at an intensity of 100 eggs per gram of stool (EPG, we estimate a sensitivity of 50% and 80% for one and two samples, respectively. At an infection intensity of 300 EPG, we estimate a sensitivity of 62% for one sample and 90% for two samples. The sensitivity for hookworm diagnosis is dominated by day-to-day variation with typical values for one, two, three, and four samples equal to 50%, 75%, 85%, and 95%, respectively, while it is only weakly dependent on the mean infection intensity in the population. We recommend taking at least two samples and estimate the 'true' prevalence of S. mansoni considering the dependence of the sensitivity on the mean infection intensity and the 'true' hookworm prevalence by taking into account the sensitivity given in the current study.

  16. More Poop, More Precision: Improving Epidemiologic Surveillance of Soil-Transmitted Helminths with Multiple Fecal Sampling using the Kato-Katz Technique.

    Liu, Chengfang; Lu, Louise; Zhang, Linxiu; Bai, Yu; Medina, Alexis; Rozelle, Scott; Smith, Darvin Scott; Zhou, Changhai; Zang, Wei

    2017-09-01

    Soil-transmitted helminths, or parasitic intestinal worms, are among the most prevalent and geographically widespread parasitic infections in the world. Accurate diagnosis and quantification of helminth infection are critical for informing and assessing deworming interventions. The Kato-Katz thick smear technique, the most widely used laboratory method to quantitatively assess infection prevalence and infection intensity of helminths, has often been compared with other methods. Only a few small-scale studies, however, have considered ways to improve its diagnostic sensitivity. This study, conducted among 4,985 school-age children in an area of rural China with moderate prevalence of helminth infection, examines the effect on diagnostic sensitivity of the Kato-Katz technique when two fecal samples collected over consecutive days are examined and compared with a single sample. A secondary aim was to consider cost-effectiveness by calculating an estimate of the marginal costs of obtaining an additional fecal sample. Our findings show that analysis of an additional fecal sample led to increases of 23%, 26%, and 100% for Ascaris lumbricoides, Trichuris trichiura , and hookworm prevalence, respectively. The cost of collecting a second fecal sample for our study population was approximately USD4.60 per fecal sample. Overall, the findings suggest that investing 31% more capital in fecal sample collection prevents an underestimation of prevalence by about 21%, and hence improves the diagnostic sensitivity of the Kato-Katz method. Especially in areas with light-intensity infections of soil-transmitted helminths and limited public health resources, more accurate epidemiological surveillance using multiple fecal samples will critically inform decisions regarding infection control and prevention.

  17. Consonant harmony in Nilotic: contrastive specifications and Stratal OT

    Sara Mackenzie

    2016-07-01

    Full Text Available Through analyses of dental harmony in four Nilotic languages, this paper argues both for contrastive representations and for a stratal version of Optimality Theory. Dholuo, Päri, Shilluk and Anywa all have dental harmony patterns which bar the co-occurrence of dental and alveolar segments. Details of the dental harmony patterning vary between languages and are tied to contrasts in the inventory. In Anywa, harmony is non-structure-preserving and an allophonic dental nasal surfaces in harmonic forms. This pattern can be analyzed in a stratal model of OT but leads to a ranking paradox if only a single level of evaluation is used. Further support for a stratal analysis can be found in the interaction between harmony and consonant mutation processes in the four languages. In Dholuo, harmony applies at the stem level and consonant mutation results in disharmonic surface forms in morphologically complex words. In Anywa, harmony applies later, at the word level, and words formed through consonant mutation must obey the dental harmony restrictions.

  18. Agreement of the Kato-Katz test established by the WHO with samples fixed with sodium acetate analyzed at 6 months to diagnose intestinal geohelminthes.

    Alfredo Fernández-Niño, Julián; David Ramírez, Juan; Consuelo López, Myriam; Inés Moncada, Ligia; Reyes, Patricia; Darío Heredia, Rubén

    2015-06-01

    The aim of this study was to evaluate the performance of the Kato-Katz test (WHO version) with stool samples from a rural area, fixed with sodium acetate (SAF). The Kato-Katz test was used to compare unfixed samples (conventional test) with the same samples containing SAF fixative at time 0 and at 6 months. The study included stools from 154 subjects. A marginally statistically significant decrease in prevalence was estimated only for hookworm, when comparing unfixed samples versus the SAF fixed samples read at 6 months (p=0.06). A significant reduction in parasite load was found for hookworm (p<0.01) and Trichuris trichiura (p<0.01) between the unfixed and the fixed sample read at 6 months, but not for Ascaris lumbricoides (p=0.10). This research suggests that the SAF fixative solution is a good option for transporting samples for diagnosis, especially in rural areas in developing countries. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. 78 FR 76768 - Removal of Transferred OTS Regulations Regarding Disclosure and Reporting of CRA-Related...

    2013-12-19

    ... of competent jurisdiction, or by operation of law. \\1\\ Dodd-Frank Wall Street Reform and Consumer... the OTS was abolished by Title III of the Dodd-Frank Act. Part 390, subpart H is largely redundant of...

  20. Inflatable capsule recovery raft using OTS pontoons and other components, Phase I

    National Aeronautics and Space Administration — The objective of the proposed innovation is to research and study the feasibility of using pontoons (based on Off the Shelf (OTS) equipment) to make an inflatable...

  1. OT2_smalhotr_3: Herschel Extreme Lensing Line Observations (HELLO)

    Malhotra, S.

    2011-09-01

    We request 59.8 hours of Herschel time to observe 20 normal star-forming galaxies in the [CII] 158 micron and [OI] 63 micron lines. These galaxies lie at high redshift (1OT1, 49 high redshift IR luminous galaxies were approved for spectroscopy, but only two so-called normal galaxies were included. This is an imbalance that should be corrected, to balance Herschel's legacy.

  2. Oxytocin (OT) and arginine-vasopressin (AVP) act on OT receptors and not AVP V1a receptors to enhance social recognition in adult Syrian hamsters (Mesocricetus auratus).

    Song, Zhimin; Larkin, Tony E; Malley, Maureen O'; Albers, H Elliott

    2016-05-01

    Social recognition is a fundamental requirement for all forms of social relationships. A majority of studies investigating the neural mechanisms underlying social recognition in rodents have investigated relatively neutral social stimuli such as juveniles or ovariectomized females over short time intervals (e.g., 2h). The present study developed a new testing model to study social recognition among adult males using a potent social stimulus. Flank gland odors are used extensively in social communication in Syrian hamsters and convey important information such as dominance status. We found that the recognition of flank gland odors after a 3min exposure lasted for at least 24h, substantially longer than the recognition of other social cues in rats and mice. Intracerebroventricular injections of OT and AVP prolonged the recognition of flank gland odor for up to 48h. Selective OTR but not V1aR agonists, mimicked these enhancing effects of OT and AVP. Similarly, selective OTR but not V1aR antagonists blocked recognition of the odors after 20min. In contrast, the recognition of non-social stimuli was not blocked by either the OTR or the V1aR antagonists. Our findings suggest both OT and AVP enhance social recognition via acting on OTRs and not V1aRs and that the recognition enhancing effects of OT and AVP are limited to social stimuli. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Comparison of individual and pooled stool samples for the assessment of intensity of Schistosoma mansoni and soil-transmitted helminth infections using the Kato-Katz technique.

    Kure, Ashenafi; Mekonnen, Zeleke; Dana, Daniel; Bajiro, Mitiku; Ayana, Mio; Vercruysse, Jozef; Levecke, Bruno

    2015-09-24

    Our group has recently provided a proof-of-principle for the examination of pooled stool samples using McMaster technique as a strategy for the rapid assessment of intensity of soil-transmitted helminth infections (STH, Ascaris lumbricoides, Trichuris trichiura and hookworm). In the present study we evaluated this pooling strategy for the assessment of intensity of both STH and Schistosoma mansoni infections using the Kato-Katz technique. A cross-sectional survey was conducted in 360 children aged 5-18 years from six schools in Jimma Zone (southwest Ethiopia). We performed faecal egg counts (FECs) in both individual and pooled samples (pools sizes of 5, 10 and 20) to estimate the number of eggs per gram of stool (EPG) using the Kato-Katz technique. We also assessed the time to screen both individual and pooled samples. Except for hookworms, there was a significant correlation (correlation coefficient = 0.53-0.95) between the mean of individual FECs and the FECs of pooled samples for A. lumbricoides, T. trichiura and S. mansoni, regardless of the pool size. Mean FEC were 2,596 EPG, 125 EPG, 47 EPG, and 41 EPG for A. lumbricoides, T. trichiura, S. mansoni and hookworm, respectively. There was no significant difference in FECs between the examination of individual and pooled stool samples, except for hookworms. For this STH, pools of 10 resulted in a significant underestimation of infection intensity. The total time to obtain individual FECs was 65 h 5 min. For pooled FECs, this was 19 h 12 min for pools of 5, 14 h 39 min for pools of 10 and 12 h 42 min for pools of 20. The results indicate that pooling of stool sample holds also promise as a rapid assessment of infections intensity for STH and S. mansoni using the Kato-Katz technique. In this setting, the time in the laboratory was reduced by 70 % when pools of 5 instead of individual stool samples were screened.

  4. Comparing the performance of circulating cathodic antigen and Kato-Katz techniques in evaluating Schistosoma mansoni infection in areas with low prevalence in selected counties of Kenya: a cross-sectional study.

    Okoyo, Collins; Simiyu, Elses; Njenga, Sammy M; Mwandawiro, Charles

    2018-04-11

    Kato-Katz technique has been the mainstay test in Schistosoma mansoni diagnosis in endemic areas. However, recent studies have documented its poor sensitivity in evaluating Schistosoma mansoni infection especially in areas with lower rates of transmission. It's the primary diagnostic tool in monitoring impact of the Kenya national school based deworming program on infection transmission, but there is need to consider a more sensitive technique as the prevalence reduces. Therefore, this study explored the relationship between results of the stool-based Kato-Katz technique with urine-based point-of-care circulating cathodic antigen (POC-CCA) test in view to inform decision-making by the program in changing from Kato-Katz to POC-CCA test. We used two cross-sectional surveys conducted pre- and post- mass drug administration (MDA) using praziquantel in a representative random sample of children from 18 schools across 11 counties. A total of 1944 children were randomly sampled for the study. Stool and urine samples were tested for S. mansoni infection using Kato-Katz and POC-CCA methods, respectively. S. mansoni prevalence using each technique was calculated and 95% confidence intervals obtained using binomial regression model. Specificity (Sp) and sensitivity (Sn) were determined using 2 × 2 contingency tables and compared using the McNemar's chi-square test. A total of 1899 and 1878 children were surveyed at pre- and post-treatment respectively. S. mansoni infection prevalence was 26.5 and 21.4% during pre- and post-treatment respectively using POC-CCA test, and 4.9 and 1.5% for pre- and post-treatment respectively using Kato-Katz technique. Taking POC-CCA as the gold standard, Kato-Katz was found to have significantly lower sensitivity both at pre- and post-treatment, Sn = 12.5% and Sn = 5.2% respectively, McNemar test χ 2 m  = 782.0, p < 0.001. In overall, the results showed a slight/poor agreement between the two methods, kappa index (k

  5. The potential for oxytocin (OT) to prevent breast cancer: a hypothesis.

    Murrell, T G

    1995-08-01

    This hypothesis proposes that carcinogens in the breast are generated by the action of superoxide free radicals released when acinal gland distension, under the influence of unopposed prolactin, causes microvessel ischaemia. Inadequate nipple care in the at-risk years leads to ductal obstruction preventing the elimination of carcinogens from the breast. The regular production of oxytocin (OT) from nipple stimulation would cause contraction of the myoepithelial cells, relieving acinal gland distension and aiding the active elimination of carcinogenic fluid from the breast. Mechanical breast pump stimulation causes an increase in plasma OT levels in the luteal but not in the follicular phase of the menstrual cycle. OT production upon nipple stimulation in the luteal phase of premenopausal, non-lactating women may be protective against the high rates of mitotic breast cell division noted at this time via the potential to block the effect of oestrogen. The epidemiology of breast cancer suggests that lengthy lactation time is beneficial. Sexual activity in nulliparous women also protects and OT levels have been shown to rise with orgasm in women and in men. OT systems in the brain are intricately linked to oestrogen and progesterone levels, and it is possible that these hormones may modify the OT secretory response both centrally and through an effect on the sensitivity of the breast. OT production with nipple care and in sex and lactation, and the reduction in cycling ovarian hormones that occurs with pregnancy, may all be important preventative factors in the development of breast cancer both pre- and post-menopausally.

  6. Performance evaluation of direct saline stool microscopy, Formol ether concentration and Kato Katz diagnostic methods for intestinal parasitosis in the absence of gold standard methods.

    Hailu, Tadesse; Abera, Bayeh

    2015-07-01

    The parasite load within the sample and the amount of sample taken during examination greatly compromise the sensitivity of direct saline stool microscopy. A cross-sectional study was conducted in March 2011 in Bahir Dar city among 778 fresh single stool samples to evaluate the performance of direct saline (DS), Kato Katz (KK) and Formol ether concentration (FEC) methods against the 'Gold' standard. Among 778 stool samples from school age children, the highest prevalence of intestinal parasites was recorded by FEC (55.1%). The sensitivity of DS, FEC and KK were 61.1%, 92.3% and 58.7%, respectively. FEC is more sensitive than DS and KK. Hence, use of the latter is preferred. © The Author(s) 2015.

  7. Comparing Diagnostic Accuracy of Kato-Katz, Koga Agar Plate, Ether-Concentration, and FLOTAC for Schistosoma mansoni and Soil-Transmitted Helminths

    Glinz, Dominik; Silué, Kigbafori D.; Knopp, Stefanie; Lohourignon, Laurent K.; Yao, Kouassi P.; Steinmann, Peter; Rinaldi, Laura; Cringoli, Giuseppe; N'Goran, Eliézer K.; Utzinger, Jürg

    2010-01-01

    Background Infections with schistosomes and soil-transmitted helminths exert a considerable yet underappreciated economic and public health burden on afflicted populations. Accurate diagnosis is crucial for patient management, drug efficacy evaluations, and monitoring of large-scale community-based control programs. Methods/Principal Findings The diagnostic accuracy of four copromicroscopic techniques (i.e., Kato-Katz, Koga agar plate, ether-concentration, and FLOTAC) for the detection of Schistosoma mansoni and soil-transmitted helminth eggs was compared using stool samples from 112 school children in Côte d'Ivoire. Combined results of all four methods served as a diagnostic ‘gold’ standard and revealed prevalences of S. mansoni, hookworm, Trichuris trichiura, Strongyloides stercoralis and Ascaris lumbricoides of 83.0%, 55.4%, 40.2%, 33.9% and 28.6%, respectively. A single FLOTAC from stool samples preserved in sodium acetate-acetic acid-formalin for 30 or 83 days showed a higher sensitivity for S. mansoni diagnosis (91.4%) than the ether-concentration method on stool samples preserved for 40 days (85.0%) or triplicate Kato-Katz using fresh stool samples (77.4%). Moreover, a single FLOTAC detected hookworm, A. lumbricoides and T. trichiura infections with a higher sensitivity than any of the other methods used, but resulted in lower egg counts. The Koga agar plate method was the most accurate diagnostic assay for S. stercoralis. Conclusion/Significance We have shown that the FLOTAC method holds promise for the diagnosis of S. mansoni. Moreover, our study confirms that FLOTAC is a sensitive technique for detection of common soil-transmitted helminths. For the diagnosis of S. stercoralis, the Koga agar plate method remains the method of choice. PMID:20651931

  8. Human gastric signet ring carcinoma (KATO-III) cell apoptosis induced by Vitex agnus-castus fruit extract through intracellular oxidative stress.

    Ohyama, Kunio; Akaike, Takenori; Imai, Masahiko; Toyoda, Hiroo; Hirobe, Chieko; Bessho, Toshio

    2005-07-01

    We have previously reported that an ethanol extract of the dried ripe fruit of Vitex agnus-castus (Vitex) displays cytotoxic activity against certain kinds of human cancer cell line resulting in the induction of apoptosis. In this paper, we investigate the molecular mechanism of apoptosis induced by Vitex using a human gastric signet ring carcinoma cell line, KATO-III. DNA fragmentation was observed in Vitex-treated KATO-III cells in a time- and dose-dependent manner. DNA fragmentation was accompanied by the following phenomena: elevation in the level of hemeoxygenase-1 protein and thioredoxin reductase mRNA; repression of Mn-superoxide dismutase and catalase mRNAs; release of cytochrome c from mitochondria into the cytosol; activation of caspases-8, -9 and -3; decrease in the level of Bcl-2, Bcl-XL and Bid protein; increase in the level of Bad protein. The intracellular oxidized state, measured using 2',7'-dichlorofluorescin diacetate, increased after Vitex treatment. While the amount of intracellular GSH decreased significantly after treatment with Vitex, the level of GSSG was unaffected. Furthermore, no significant perturbation in the amount of proteins/mRNAs related to glutathione metabolism could be detected. These apoptotic alterations induced by exposure to Vitex were blocked by the presence of an anti-oxidative reagent, N-acetyl-l-cysteine, or the addition of exogenous GSH. Our results demonstrate that intracellular oxidative stress and mitochondrial membrane damage is responsible for Vitex-induced apoptosis, which may be mediated by a diminution of reduced type glutathione within the cell.

  9. Quantitative toxoplasma gondii oocyst detection by a modified Kato Katz test using Kinyoun staining (KKK in ME49 strain experimentally infected cats Detecção quantitativa de oocistos de Toxoplasma gondii, por um teste modificado de Kato Katz usando coloração de Kinyoun (KKK, em gatos infectados experimentalmente com a cepa ME49

    Luciana Regina Meireles

    2008-06-01

    Full Text Available We detected Toxoplasma gondii oocysts in feces of experimentally infected cats, using a Kato Katz approach with subsequent Kinyoun staining. Animals serologically negative to T. gondii were infected orally with 5x10² mice brain cysts of ME49 strain. Feces were collected daily from the 3rd to the 30th day after challenge. Oocysts were detected by qualitative sugar flotation and the quantitative modified Kato Katz stained by Kinyoun (KKK. In the experimentally infected cats, oocysts were detected from the 7th to 15th day through sugar flotation technique, but oocysts were found in KKK from the 6th to 16th day, being sensitive for a larger period, with permanent documentation. The peak of oocysts excretion occurred between the 8th to 11th days after challenge, before any serological positive result. KKK could be used in the screening and quantification of oocysts excretion in feces of suspected animals, with reduced handling of infective material, decreasing the possibility of environmental and operator contamination.Detectamos oocistos de Toxoplasma gondii em fezes de gatos experimentalmente infectados, usando a abordagem de Kato Katz, com subseqüente coloração pelo método de Kinyoun. Animais sorologicamente negativos ao T. gondii foram infectados por via oral com 5x10² cistos da cepa ME49 de cérebros de camundongos. Fezes foram colhidas diariamente a partir do 3º até o 30º dia pós-infecção. Oocistos foram detectados por centrífugo-flutuação em sacarose qualitativa e pelo método quantitativo de Kato Katz modificado corado pela técnica de Kinyoun (KKK. Em gatos experimentalmente infectados, oocistos foram detectados do 7º ao 15º dia pela técnica de centrífugo-flutuação em sacarose, mas oocistos foram detectados do 6º ao 16º dia pelo KKK, sendo sensível por um período maior, com documentação permanente. O pico da excreção de oocistos ocorreu entre 8º a 11º dia pós-infecção, antes de resultado sorológico positivo

  10. Performance of non-ideal OT-MRC with co-channel interference

    Radaydeh, Redha Mahmoud Mesleh

    2010-12-01

    This paper studies the effect of non-ideal estimation of channel state information (CSI) on the performance of output-threshold maximal-ratio combining (OT-MRC) diversity scheme in the presence of co-channel interference as well as white noise. The channel fading envelopes are assumed to follow slowly varying flat Rayleigh model. New closed-form expressions for the combined signal-to-interference-plus-noise ratio (SINR) distribution and outage probability performance are presented. Performance comparisons between the conventional MRC and OT-MRC for the system model described above are provided. © 2010 IEEE.

  11. MASTER OT J072007.30+451611.6: Cataclysmic Variable with an Extreme Hot Spot

    Denisenko, D.

    2018-05-01

    MASTER team has reported an unusual object MASTER OT J072007.30+451611.6 in ATel #11620 (T. Pogrosheva et al.). The object was observed at 17.0-17.2m during 9 minutes from 22:15:26 to 22:24:30 UT on 2018-04-26, but was below the detection limit (18.8m) 45 minutes before the first positive observation and 43 minutes after the last one. As noted by S. Otero in AAVSO VSX entry, MASTER OT J072007.30+451611.6 has an X-ray counterpart XMMSL2 J072007.4+451615.

  12. 12 CFR 502.28 - How does OTS determine the organizational form component for a savings and loan holding company?

    2010-01-01

    ... component for a savings and loan holding company? 502.28 Section 502.28 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES Assessments Savings and Loan Holding Companies... savings and loan holding company that OTS regulates under section 10(l) of the HOLA. OTS will compute your...

  13. Optimal Diphthongs: An OT Analysis of the Acquisition of Spanish Diphthongs

    Krause, Alice

    2013-01-01

    This dissertation investigates the acquisition of Spanish diphthongs by adult native speakers of English. The following research questions will be addressed: 1) How do adult native speakers of English pronounce sequences of two vowels in their L2 Spanish at different levels of acquisition? 2) Can OT learnability models, specifically the GLA,…

  14. 12 CFR 563b.200 - What actions may OTS take on my application?

    2010-01-01

    ... appraiser may serve as an underwriter or selling agent, if you ensure that the appraiser is separate from the underwriter or selling agent affiliate and the underwriter or selling agent affiliate does not... convenience and needs of your communities after the conversion. (1) Based on this review, OTS may approve your...

  15. Use of thermal cycling to reduce adhesion of OTS coated coated MEMS cantilevers

    Ali, Shaikh M.; Phinney, Leslie M.

    2003-01-01

    °Microelectromechanical systems (MEMS) have enormous potential to contribute in diverse fields such as automotive, health care, aerospace, consumer products, and biotechnology, but successful commercial applications of MEMS are still small in number. Reliability of MEMS is a major impediment to the commercialization of laboratory prototypes. Due to the multitude of MEMS applications and the numerous processing and packaging steps, MEMS are exposed to a variety of environmental conditions, making the prediction of operational reliability difficult. In this paper, we investigate the effects of operating temperature on the in-use adhesive failure of electrostatically actuated MEMS microcantilevers coated with octadecyltrichlorosilane (OTS) films. The cantilevers are subjected to repeated temperature cycles and electrostatically actuated at temperatures between 25°C and 300°C in ambient air. The experimental results indicate that temperature cycling of the OTS coated cantilevers in air reduces the sticking probability of the microcantilevers. The sticking probability of OTS coated cantilevers was highest during heating, which decreased during cooling, and was lowest during reheating. Modifications to the OTS release method to increase its yield are also discussed.

  16. Spectroscopic Classification of MASTER OT J110707.62-052244.0 as a Type Ia Supernova

    Zheng, W.; Kim, M.; Shivvers, I.; Yuk, H.; Filippenko, A. V.

    2015-11-01

    We report that inspection of a CCD spectrum (range 350-1050 nm) of MASTER OT J110707.62-052244.0 (ATel #8236), obtained on Nov. 11.57 UT with the Shane 3-m reflector (+ Kast spectrograph) at Lick Observatory, shows that the object is a normal Type Ia supernova roughly 1 week past maximum brightness.

  17. Spectroscopic Classification of MASTER OT J044212.20+230616.7

    Shivvers, I.; Kelly, P. L.; Clubb, K. I.; Filippenko, A. V.

    2014-09-01

    We report that inspection of a CCD spectrum (range 330-1000 nm), obtained on September 22 UT with the 3-m Shane reflector (+ Kast) at Lick Observatory, shows that MASTER OT J044212.20+230616.7 (ATel #6484) is a Type IIn supernova.

  18. 78 FR 54401 - Removal of Transferred OTS Regulations Regarding Post-Employment Activities of Senior Examiners

    2013-09-04

    ... F Street) on business days between 7 a.m. and 5 p.m. Please include your name, affiliation, address... section 6303(b) of the Intelligence Reform and Terrorism Prevention Act of 2004.\\4\\ This Act added a new... showing of good cause. After comparing the FDIC's rules with the transferred OTS rule relating to post...

  19. Nedožité devadesátiny Milana Otáhala

    Tůma, Oldřich

    2017-01-01

    Roč. 24, 1/2 (2017), s. 247-251 ISSN 1210-7050 Institutional support: RVO:68378114 Keywords : Milan Otáhal * obituary * historiography Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  20. Doktoritööd : [2007, Janis Ešots, Signe Dobelniece

    2007-01-01

    29. mail kaitseb Janis Ešots doktoritööd "Mullā Sadrā wujūd õpetus: müstitsismi ja filosoofia süntees"; 11. juunil kaitseb Signe Dobelniece doktoritööd "Kodutus Lätis: põhjused ja lahendused"

  1. "Merging Yoga and Occupational Therapy (MY-OT): A feasibility and pilot study".

    Schmid, Arlene A; Puymbroeck, Marieke Van; Portz, Jennifer D; Atler, Karen E; Fruhauf, Christine A

    2016-10-01

    To examine the feasibility and benefits of the Merging Yoga and Occupational Therapy (MY-OT) intervention. This is the primary analysis of a non-controlled pretest-posttest pilot study to understand the feasibility and impact of MY-OT on balance, balance self-efficacy, and fall risk factor management in people with chronic stroke. University research laboratory. People with chronic stroke were included in the study if they: had sustained a fall or had fear of falling, were able to stand, and hand impaired balance and were at risk for falls (≤46 on the Berg Balance Scale (BBS)). Individuals completed an 8 week intervention that included 16 sessions of both yoga and group occupational therapy (OT). Yoga included physical postures, breathing exercises, and meditation. OT focused on post-stroke fall risk factor management. The BBS was used to assess balance, the Activities-specific Balance Confidence Scale (ABC) was used to measure balance self-efficacy. Five fall risk factor management scales were used. Overall, the intervention was considered feasible, as individuals were able to safely complete the intervention with little attrition and high attendance. Balance improved by 30% (p=0.002). Balance self-efficacy improved by 15% (p=0.034). Each of the five fall risk factor management scales improved, but only two significantly improved (Fall Prevention and Management Questionnaire, 29%, p=0.004 and Fall Prevention Strategy Survey, 42%, p=0.032). The results demonstrate that MY-OT is a potential intervention to improve multiple fall related outcomes for people with stroke. Therapists may consider these interventions for people with stroke, but additional research is warranted. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Increased detection of schistosomiasis with Kato-Katz and SWAP-IgG-ELISA in a Northeastern Brazil low-intensity transmission area

    Teiliane Rodrigues Carneiro

    2012-08-01

    Full Text Available INTRODUCTION: The laboratory diagnosis of schistosomiasis is based mainly on the detection of parasite eggs in stool samples through the Kato-Katz (KK technique, reading one slide by test. However, a widely known limitation of parasitological methods is reduced sensitivity, particularly in low endemic areas. METHODS: To increase sensitivity, we conducted further slide readings from the same stool sample using the parasitological method associated with a serological test. We used the KK method (three slides and the IgG anti-Schistosoma mansoni-enzyme-linked immunosorbent assay (ELISA technique to diagnose schistosomiasis in low endemic areas in the Brazilian State of Ceará. Fecal samples and sera from 250 individuals were analyzed. RESULTS: Sixteen percent and 47.2% of samples were positive in parasitological tests and serological tests, respectively. Parasitological methods showed that 32 (80% individuals tested positive on the first slide, 6 (15% on the second slide, and 2 (5% on the third. The performance of the ELISA test in the diagnosis, using the KK method as diagnostic reference, showed a negative predictive value of 100%, with specificity and positive predictive values of 62.8% and 33.9%, respectively. CONCLUSIONS: In this study, the increase from one to three slides analyzed per sample using the KK technique was shown to be a useful procedure for increasing the diagnostic sensitivity of this technique.

  3. PREDICTING PROGNOSTIC VALUE OF OCULAR TRAUMA SCORE (OTS IN AN OPEN GLOBE INJURY IN TERTIARY EYE CARE HOSPITAL

    Rahul

    2015-10-01

    Full Text Available AIM : To evaluate the prognostic value of OTS in open globe injuries. MATERIAL METHOD : Retrospective analysis of 77 eyes with open globe injuries was done from 01/07/2013 to 31/12/2014. Patients were assigned raw score sum based on initial V/A, and ocular findings then classified into 5 categories for predicting final visual outcome based on ocular Trauma score (OTS. RESULT : We estimated final V/A in 77 cases of open globe injuries (64.93% had raw sc ore between 65.91 (category 3, 4 Six months after the injury, 42.85% patients of categories 1 (raw score 0 - 44 achieved V/A of PL/HM as compared to 17% in OTS study. 16 patients with raw compared to OTS study. We reported comparable visual outcome with OT S study except in category 1 & 2. CONCLUSION: OTS score is valuable in triage, patient counseling and decision making for the management of ocular trauma. We recommend that OTS should be used routinely for open globe injuries as it is a simple guide

  4. MASTER OT J014638.27+041324.4 is a Young Type IIP Supernova

    Zheng, W.; Kelly, P. L.; Clubb, K. I.; Filippenko, A. V.

    2013-12-01

    We report that a CCD spectrum (range 350-1000 nm) of MASTER OT J014638.27+041324.4 (Shurpakov et al., ATel #5630) was obtained on Dec 6.5 UT with the Shane 3-m reflector (+Kast spectrograph) at Lick Observatory. The spectrum shows a blue continuum and weak, broad hydrogen Balmer lines having P-Cyg profiles, indicating that the object is a young Type IIP supernova. Weak He I 587.6 nm is also present.

  5. Mis mõtteid tekitab õpetaja kutsestandardi projekt? / Kerli Prass, Kalle Kalda, Loone Ots, Külli Arand

    2013-01-01

    Vastasid SA Noored Kooli tuutor ja õpetajakoolituse koordinaator Kerli Prass, lastekaitse liidu president Loone Ots, Tartu haridustöötajate liidu esimees Kalle Kalda, Tallinna Saksa Gümnaasiumi klassiõpetaja Külli Arand

  6. Computer software design description for the Treated Effluent Disposal Facility (TEDF), Project L-045H, Operator Training Station (OTS)

    Carter, R.L. Jr.

    1994-01-01

    The Treated Effluent Disposal Facility (TEDF) Operator Training Station (OTS) is a computer-based training tool designed to aid plant operations and engineering staff in familiarizing themselves with the TEDF Central Control System (CCS)

  7. Placental Expressions of CDKN1C and KCNQ1OT1 in Monozygotic Twins with Selective Intrauterine Growth Restriction.

    Gou, Chenyu; Liu, Xiangzhen; Shi, Xiaomei; Chai, Hanjing; He, Zhi-Ming; Huang, Xuan; Fang, Qun

    2017-10-01

    CDKN1C and KCNQ1OT1 are imprinted genes that might be potential regulators of placental development. This study investigated placental expressions of CDKN1C and KCNQ1OT1 in monozygotic twins with and without selective intrauterine growth restriction (sIUGR). Seventeen sIUGR and fifteen normal monozygotic(MZ) twin pairs were examined. Placental mRNA expressions of CDKN1C and KCNQ1OT1 were detected by real-time fluorescent quantitative PCR. CDKN1C protein expression was detected by immunohistochemical assay and Western-blotting. In the sIUGR group, smaller fetuses had a smaller share of the placenta, and CDKN1C protein expression was significantly increased while KCNQ1OT1 mRNA expression was significantly decreased. The CDKN1C/KCNQ1OT1 mRNA ratio was lower in the larger fetus than in the smaller fetus (p < .05). In the control group, CDKN1C protein expression showed no difference between larger and smaller fetuses, while KCNQ1OT1 mRNA expression was significantly lower in the larger fetus, and the CDKN1C/KCNQ1OT1 mRNA ratio was higher in the larger fetus than in the smaller fetus (p < .05). Our findings showed that pathogenesis of sIUGR may be related to the co-effect of the up-regulated protein expression of CDKN1C and down-regulated mRNA expression of KCNQ1OT1 in the placenta.

  8. Gene expression profiles of prohibitin in testes of Octopus tankahkeei (ot-phb) revealing its possible role during spermiogenesis.

    Mao, Hai-Tao; Wang, Da-Hui; Lan, Zhou; Zhou, Hong; Yang, Wan-Xi

    2012-05-01

    Prohibitin is essential for intracellular homeostasis and stabilization of mitochondrial respiratory chain complexes. To explore its functions during spermiogenesis of Octopus tankahkeei (O. tankahkeei), we have cloned and sequenced the cDNA of this mammalian PHB homologue (termed ot-PHB) from the testes of O. tankahkeei. The 1165 bp ot-phb cDNA contains a 100 bp 5' UTR, a 882 bp open reading frame and a 183 bp 3' UTR. The putative ot-PHB protein owns a transmembrane domain from 6 to 31 amino acid (aa) and a putative PHB domain from 26 to 178 aa. Protein alignment demonstrated that ot-PHB had 73.3, 73.6, 74.0, 75.1, and 45.4% identity with its homologues in Homo sapiens, Mus muculus, Danio rerio, Xenopus tropicalis and Trypanosoma brucei, respectively. Tissue distribution profile analysis revealed its presence in all the tissues examined. In situ hybridization in spermiogenic cells demonstrated that ot-phb was expressed moderately at the beginning of the spermiogenesis. The abundance of transcripts increased in intermediate spermatids and in drastically remodeling final spermatids. In mature spermatozoa, the residuary transcripts concentrated around the chondriosomal mantle where mitochondria assemble around. In summary, the expression of ot-phb during spermiogenesis implicates a potential function of this protein during mitochondrial ubiquitination. It is the first time to implicate the role of prohibitin in cephalopod spermiogenesis.

  9. The reactivity of anion-exchange resins by applying OT-for-OH exchange reaction in the equilibrium state

    Kano, Naoki; Nihei, Makoto; Imaizumi, Hiroshi

    1996-01-01

    In order to reveal the behavior of hydroxyl group in isotope exchange reaction, OT-for-OH exchange reaction between each anion-exchange resin (OH - form) and tritiated water (abbreviated as HTO water below) was observed at 80degC under the equilibrium. Anion-exchange resins used were Amberlite IRA-400, IRA-410 (both strongly basic), and IRA-94S (weakly basic). It can be thought that an HTO molecule dissociates into H + +OT - (or T + +OH - ). The activity of each resin based on OT-for-OH exchange reaction was measured with a liquid scintillation counter. From the above-mentioned, the following five were found. Isotope exchange reaction as 'atomic group' occurred between the OH group in each anion-exchange resin and the OT group in HTO water. The reactivity of strongly basic anion-exchange resin is larger than that of weakly basic one. The ratio of the reactivity of these resins can roughly be expressed as follows: (IRA-410): (IRA-400): (IRA-94S)=42: 7: 1. The degree of OT-for-OH exchange reaction may be smaller than that of T-for-H exchange reaction. The method used and results obtained in this work may be helpful to obtain the data for the prevention of T-contamination, especially to obtain the data from certain atomic groups including T. (author)

  10. Solar-energy-system performance evaluation: Honeywell OTS 44, Ocmulgee, Georgia

    Mathur, A. K.; Pederson, S.

    1982-01-01

    The operation and technical performance of the solar operational test site (OTS 44) are described, based on data collected between April, 1981 and August, 1981. The following topics are discussed: system description, performance assessment, operating energy, energy savings, system maintenance, and conclusions. The solar energy system at OTS 44 is a hydronic heating and cooling system consisting of 5040 square feet of liquid cooled flat plate collectors; a 4000 gallon thermal storage tank; one 25 ton capacity organic Rankine cycle engine assisted water chillers; a forced draft cooling tower; and associated piping, pumps, valves, controls and heat rejection equipment. The solar system has eight basic modes of operation and several combination modes for providing space conditioning and hot water to the building. Data monitored during the 4 months of the operational test period found that the solar system collected 285 MMBtu of thermal energy of the total incident solar energy of 1040 MMBtu and provided 210 MMBtu for cooling and 10 MMBtu for heating and hot water. The net electrical energy saving due to the solar system was approximately 2600 kWh(e), and fossil energy saving was about 20 million Btu (MMBtu).

  11. Solar energy system performance evaluation: Honeywell OTS 41, Shenandoah (Newman), Georgia

    Mathur, A. K.; Pederson, S.

    1982-08-01

    The operation and technical performance of the Solar Operational Test Site (OTS 41) located at Shenandoah, Georgia, are described, based on the analysis of the data collected between January and August 1981. The following topics are discussed: system description, performance assessment, operating energy, energy savings, system maintenance, and conclusions. The solar energy system at OTS 41 is a hydronic heating and cooling system consisting of 702 square feet of liquid-cooled flat-plate collectors; a 1000-gallon thermal storage tank; a 3-ton capacity organic Rankine-cycle-engine-assisted air conditioner; a water-to-are heat exchanger for solar space heating; a finned-tube coil immersed in the storage tank to preheat water for a gas-fired hot water heater; and associated piping, pumps, valves, and controls. The solar system has six basic modes of operation and several combination modes. The system operation is controlled automatically by a Honeywell-designed microprocessor-based control system, which also provides diagnostics.

  12. In a changing society which elements and competencies is needed and demanded in the future OT education?

    Hansen, Bodil Winther; Sørensen, Annette

    to plan a curriculum, in order to enable OT graduates to meet employers’ demands in a rapidly changing society •The future OT profession. After 12 years of practising Problem Based Learning (PBL), the Faculty of Occupational Therapy wanted to develop the quality of the OT education offered by Metropolitan...... University College, Copenhagen. The object was to evaluate and develop the pedagogical practice, and to examine if the pedagogical concept prepares the students for the future in the best way possible. To describe the level of education to be achieved in terms of competences and learning outcome, the study...... was inspired by the Tuning Process of educational structures in Europe, which is part of the Bologna process to integrate higher education in Europe. The study is based on literature studies, quantitative and qualitative methods. All of these methods are suitable for uncovering competences demanded by practice...

  13. High-Amplitude, Rapid Photometric Variation of the New Polar Master OT J132104.0+560957.8

    2015-02-05

    HIGH-AMPLITUDE, RAPID PHOTOMETRIC VARIATION OF THE NEW POLAR MASTER OT J132104.04+560957.8 LITTLEFIELD, COLIN;1,2 GARNAVICH, PETER;1 MAGNO, KATRINA;1...18.5 during each photometric cycle, becoming so faint that we could no longer detect it. The data showed a period of roughly 91 minutes with each...TYPE 3. DATES COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE High-Amplitude, Rapid Photometric Variation Of The New Polar Master OT

  14. Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.

    Jan Korte

    2016-12-01

    Full Text Available Trehalose biosynthesis is considered an attractive target for the development of antimicrobials against fungal, helminthic and bacterial pathogens including Mycobacterium tuberculosis. The most common biosynthetic route involves trehalose-6-phosphate (T6P synthase OtsA and T6P phosphatase OtsB that generate trehalose from ADP/UDP-glucose and glucose-6-phosphate. In order to assess the drug target potential of T6P phosphatase, we generated a conditional mutant of M. tuberculosis allowing the regulated gene silencing of the T6P phosphatase gene otsB2. We found that otsB2 is essential for growth of M. tuberculosis in vitro as well as for the acute infection phase in mice following aerosol infection. By contrast, otsB2 is not essential for the chronic infection phase in mice, highlighting the substantial remodelling of trehalose metabolism during infection by M. tuberculosis. Blocking OtsB2 resulted in the accumulation of its substrate T6P, which appears to be toxic, leading to the self-poisoning of cells. Accordingly, blocking T6P production in a ΔotsA mutant abrogated otsB2 essentiality. T6P accumulation elicited a global upregulation of more than 800 genes, which might result from an increase in RNA stability implied by the enhanced neutralization of toxins exhibiting ribonuclease activity. Surprisingly, overlap with the stress response caused by the accumulation of another toxic sugar phosphate molecule, maltose-1-phosphate, was minimal. A genome-wide screen for synthetic lethal interactions with otsA identified numerous genes, revealing additional potential drug targets synergistic with OtsB2 suitable for combination therapies that would minimize the emergence of resistance to OtsB2 inhibitors.

  15. Characterization of an immunodominant cancer-specific O-glycopeptide epitope in murine podoplanin (OTS8)

    Steentoft, Catharina; Schjoldager, Katrine T; Cló, Emiliano

    2010-01-01

    antibody 237, developed to a spontaneous murine fibrosarcoma, was shown to be directed to murine podoplanin (OTS8) with truncated Tn O-glycans. Our understanding of such cancer-specific auto-antibodies to truncated glycoforms of glycoproteins is limited. Here we have investigated immunogenicity...... of a chemoenzymatically produced Tn-glycopeptide derived from the putative murine podoplanin O-glycopeptide epitope. We found that the Tn O-glycopeptide was highly immunogenic in mice and produced a Tn-glycoform specific response with no reactivity against unglycosylated peptides or the O-glycopeptide with extended O......-glycan (STn and T glycoforms). The immunodominant epitope was strictly dependent on the peptide sequence, required Tn at a specific single Thr residue (Thr(77)), and antibodies to the epitope were not found in naive mice. We further tested a Tn O-glycopeptide library derived from human podoplanin...

  16. Entraining IDyOT: timing in the information dynamics of thinking

    Jamie Forth

    2016-10-01

    Full Text Available We present a novel hypothetical account of entrainment in music and language, in context of the Information Dynamics of Thinking model, IDyOT. The extended model affords an alternative view of entrainment, and its companion term, pulse, from earlier accounts. The model is based on hiearchical, statistical prediction, modeling expectations of both what an event will be and when it will happen. As such,it constitutes a kind of predictive coding, with a particular novel hypothetical implementation. Here, we focus on the model’s mechanism for predicting when a perceptual event will happen, given an existing sequence of past events, which maybe musical or linguistic. We propose a range of tests to validate or falsify the model, at various different levels of abstraction, and argue that computational modelling in particular, and this model in particular, can offer a means of providing limited but useful evidence for evolutionary hypotheses.

  17. 75 FR 181 - Application for Conversion From: (a) OTS-Regulated, State-Chartered Savings Association to...

    2010-01-04

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Application for Conversion From: (a) OTS-Regulated, State- Chartered Savings Association to Federal Savings Association; (b) National Bank, Commercial Bank, State Savings Bank, or Credit Union to Federal Savings Association; (c) State Mutual Holding...

  18. 75 FR 10560 - Application for Conversion From: (a) OTS-Regulated, State-Chartered Savings Association to...

    2010-03-08

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Application for Conversion From: (a) OTS-Regulated, State- Chartered Savings Association to Federal Savings Association; (b) National Bank, Commercial Bank, State Savings Bank, or Credit Union to Federal Savings Association; (c) State Mutual Holding...

  19. 12 CFR 502.29 - How does OTS determine the condition component for a savings and loan holding company?

    2010-01-01

    ... for a savings and loan holding company? 502.29 Section 502.29 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES Assessments Savings and Loan Holding Companies-Calculation of Assessments § 502.29 How does OTS determine the condition component for a savings and loan...

  20. 12 CFR 502.26 - How does OTS calculate the semi-annual assessment for savings and loan holding companies?

    2010-01-01

    ... assessment for savings and loan holding companies? 502.26 Section 502.26 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES Assessments Savings and Loan Holding Companies-Calculation of Assessments § 502.26 How does OTS calculate the semi-annual assessment for savings and loan...

  1. Comparison of Kato-Katz thick-smear and McMaster egg counting method for the assessment of drug efficacy against soil-transmitted helminthiasis in school children in Jimma Town, Ethiopia.

    Bekana, Teshome; Mekonnen, Zeleke; Zeynudin, Ahmed; Ayana, Mio; Getachew, Mestawet; Vercruysse, Jozef; Levecke, Bruno

    2015-10-01

    There is a paucity of studies that compare efficacy of drugs obtained by different diagnostic methods. We compared the efficacy of a single oral dose albendazole (400 mg), measured as egg reduction rate, against soil-transmitted helminth infections in 210 school children (Jimma Town, Ethiopia) using both Kato-Katz thick smear and McMaster egg counting method. Our results indicate that differences in sensitivity and faecal egg counts did not imply a significant difference in egg reduction rate estimates. The choice of a diagnostic method to assess drug efficacy should not be based on sensitivity and faecal egg counts only. © The Author 2015. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  2. Effect of Ozone Therapy (OT on Healing of Colonic Anastomosis in a Rat Model of Peritonitis

    Başak Erginel

    2014-09-01

    Full Text Available Background: Ozone is a three-oxygen molecule (O3. Ozone therapy (OT is systematically effective when pathological inflammatory and immunologic processes are activated. Among of these conditions are wound healing, macular degeneration related to aging, and conditions that are ischemic or infectious. Aims: The aim of this study was to determine the effects of OT on wound healing of intestinal anastomosis in the presence of peritonitis in a rat model. Study Design: Animal experimentation. Methods: A total of 40 Wistar albino rats were randomized into four groups (n=10 including: sham (S, peritonitis (P, ozone 0 (O0, and ozone 24 (O24. In group S, only cecal dissection was carried out. The S group had only a cecal dissection and intestinal anastomosis performed, but no peritonitis. In all other groups, cecal ligation and puncture (CLP followed the cecal dissection to induce bacterial peritonitis. 24 h after puncture, a cecal resection and ileocolic anastomosis were performed. In group P, 24 h after CLP, a cecal resection and ileocolic anastomosis were performed and no ozone was administered. In group O0, immediately after the anastomosis, and in group O24, starting 24 hours after the anastomosis, an intraperitoneal 1 mg/kg/day ozone administration was applied for seven days. On the seventh day the animals were sacrificed, the anastomotic bursting pressures (BP and the hydroxyproline values of the anastomotic tissues were measured, and histopathologic examination of the anastomotic segment was carried out. Results: The highest BP was in group S, with 211±23.13 mmHg. The mean BP of group P was 141±56.25 mmHg, which was significantly lower than in the other two peritonitis groups that received ozone therapy, group O0 and O24, where it was 192±22 and 166±45 mmHg, respectively (p0.05. Histopathologic analyses of the anastomotic segments determined there was significantly more oedema and necrosis in the control group rats, and collagen deposition in

  3. Over-expression of the mycobacterial trehalose-phosphate phosphatase OtsB2 results in a defect in macrophage phagocytosis associated with increased mycobacterial-macrophage adhesion

    Hao Li

    2016-11-01

    Full Text Available Trehalose-6-phosphate phosphatase (OtsB2 is involved in the OtsAB trehalose synthesis pathway to produce free trehalose and is strictly essential for mycobacterial growth. We wished to determine the effects of OtsB2 expression on mycobacterial phenotypes such as growth, phagocytosis and survival in macrophages. Mycobacterium bovis-BCG (BCG over-expressing OtsB2 were able to better survive in stationary phase. Over-expression of OtsB2 led to a decrease in phagocytosis but not survival in THP-1 macrophage-like cells, and this was not due to a decrease in general macrophage phagocytic activity. Surprisingly, when we investigated macrophage-mycobacterial interactions by flow cytometry and atomic force microscopy, we discovered that BCG over-expressing OtsB2 have stronger binding to THP-1 cells than wild-type BCG. These results suggest that altering OtsB2 expression has implications for mycobacterial host-pathogen interactions. Macrophage-mycobacteria phagocytic interactions are complex and merit further study.

  4. Isolation and Pharmacological Characterization of α-Elapitoxin-Ot1a, a Short-Chain Postsynaptic Neurotoxin from the Venom of the Western Desert Taipan, Oxyuranus temporalis

    Carmel M. Barber

    2016-02-01

    Full Text Available Taipans (Oxyuranus spp. are elapids with highly potent venoms containing presynaptic (β and postsynaptic (α neurotoxins. O. temporalis (Western Desert taipan, a newly discovered member of this genus, has been shown to possess venom which displays marked in vitro neurotoxicity. No components have been isolated from this venom. We describe the characterization of α-elapitoxin-Ot1a (α-EPTX-Ot1a; 6712 Da, a short-chain postsynaptic neurotoxin, which accounts for approximately 30% of O. temporalis venom. α-Elapitoxin-Ot1a (0.1–1 µM produced concentration-dependent inhibition of indirect-twitches, and abolished contractile responses to exogenous acetylcholine and carbachol, in the chick biventer cervicis nerve-muscle preparation. The inhibition of indirect twitches by α-elapitoxin-Ot1a (1 µM was not reversed by washing the tissue. Prior addition of taipan antivenom (10 U/mL delayed the neurotoxic effects of α-elapitoxin-Ot1a (1 µM and markedly attenuated the neurotoxic effects of α-elapitoxin-Ot1a (0.1 µM. α-Elapitoxin-Ot1a displayed pseudo-irreversible antagonism of concentration-response curves to carbachol with a pA2 value of 8.02 ± 0.05. De novo sequencing revealed the main sequence of the short-chain postsynaptic neurotoxin (i.e., α-elapitoxin-Ot1a as well as three other isoforms found in O. temporalis venom. α-Elapitoxin-Ot1a shows high sequence similarity (i.e., >87% with other taipan short-chain postsynaptic neurotoxins.

  5. A global outer-rise/outer-trench-slope (OR/OTS) earthquake study

    Wartman, J. M.; Kita, S.; Kirby, S. H.; Choy, G. L.

    2009-12-01

    Using improved seismic, bathymetric, satellite gravity and other geophysical data, we investigated the seismicity patterns and focal mechanisms of earthquakes in oceanic lithosphere off the trenches of the world that are large enough to be well recorded at teleseismic distances. A number of prominent trends are apparent, some of which have been previously recognized based on more limited data [1], and some of which are largely new [2-5]: (1) The largest events and the highest seismicity rates tend to occur where Mesozoic incoming plates are subducting at high rates (e.g., those in the western Pacific and the Banda segment of Indonesia). The largest events are predominantly shallow normal faulting (SNF) earthquakes. Less common are reverse-faulting (RF) events that tend to be deeper and to be present along with SNF events where nearby seamounts, seamount chains and other volcanic features are subducting [Seno and Yamanaka, 1996]. Blooms of SNF OR/OTS events usually occur just after and seaward of great interplate thrust (IPT) earthquakes but are far less common after smaller IPT events. (2) Plates subducting at slow rates (Chile, the Ninety East Ridge in Sumatra, and the D’Entrecastaux Ridge in Vanuatu).

  6. Evaluation of a Coaching Experiential Learning Project on OT Student Abilities and Perceptions

    Erin A. Phillips

    2017-01-01

    Full Text Available Innovative teaching methods to address emerging practice needs are critical components of effective occupational therapy education. Experiential learning strategies can enhance skill development and translation of knowledge into OT clinical practice. In addition, skills such as coaching may provide important links to health promotion practices. Thirty-two occupational therapy students took part in an experiential project to connect occupational engagement and health for a community of older adults. A pretest/posttest design was used to evaluate program outcomes in student perceived abilities, and narrative reflection papers provided postexperience qualitative information. The students improved in all 10 areas of abilities selfassessment with mean total scores from pretest (M = 42 improving significantly at posttest (M = 58. Themes from reflection papers indicated a positive response to experiential learning and a desire for more opportunities to prepare for clinical practice, including the use of interprofessional training. The students improved in their abilities to use coaching and health promotion strategies through the use of experiential learning methods. Outcomes suggest that experiential learning opportunities are an effective way to enhance student competencies in coaching, improve readiness for wellness programming, and increase student confidence in application of skills in future clinical practice.

  7. Secondary Metabolite Profiling of Species of the Genus Usnea by UHPLC-ESI-OT-MS-MS

    Francisco Salgado

    2017-12-01

    Full Text Available Lichens are symbiotic associations of fungi with microalgae and/or cyanobacteria, which are considered among the slowest growing organisms, with strong tolerance to adverse environmental conditions. There are about 400 genera and 1600 species of lichens and those belonging to the Usnea genus comprise about 360 of these species. Usnea lichens have been used since ancient times as dyes, cosmetics, preservatives, deodorants and folk medicines. The phytochemistry of the Usnea genus includes more than 60 compounds which belong to the following classes: depsides, depsidones, depsones, lactones, quinones, phenolics, polysaccharides, fatty acids and dibenzofurans. Due to scarce knowledge of metabolomic profiles of Usnea species (U. barbata, U. antarctica, U. rubicunda and U. subfloridana, a study based on UHPLC-ESI-OT-MS-MS was performed for a comprehensive characterization of their secondary metabolites. From the methanolic extracts of these species a total of 73 metabolites were identified for the first time using this hyphenated technique, including 34 compounds in U. barbata, 21 in U. antarctica, 38 in U. rubicunda and 37 in U. subfloridana. Besides, a total of 13 metabolites were not identified and reported so far, and could be new according to our data analysis. This study showed that this hyphenated technique is rapid, effective and accurate for phytochemical identification of lichen metabolites and the data collected could be useful for chemotaxonomic studies.

  8. {sigma}{sup t}ot{sub e}eyy at e{sup +}e{sup -} colliders

    Godbole, R.M. [Indian Institute of Science, Centre for Theoretical Studies, Bangalore (India); Pancheri, G. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati, Rome (Italy)

    2001-02-01

    In this talk are briefly summarized different models for {sigma}{sup t}ot{sub 2}y (e{sup +}e{sup -} {yields}yy{yields} hadrons) and contrast model predictions with the data. It will be then discussed the capability of the future e{sup +}e{sup -} and yy colliders to distinguish between various models and end with an outlook for future work.

  9. Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial.

    Wong, Wai T; Kam, Waynekid; Cunningham, Denise; Harrington, Molly; Hammel, Keri; Meyerle, Catherine B; Cukras, Catherine; Chew, Emily Y; Sadda, Srinivas R; Ferris, Frederick L

    2010-12-01

    To investigate the safety and preliminary efficacy of OT-551, a disubstituted hydroxylamine with antioxidant properties, for the treatment of geographic atrophy (GA), the advanced atrophic form of age-related macular degeneration (AMD). The study was a single-center, open-label phase II trial, enrolling 10 participants with bilateral GA. Topical 0.45% OT-551 was administered in one randomly assigned eye three times daily for 2 years. Safety measures were assessed by complete ophthalmic examination, fundus photography, and review of symptoms. The primary efficacy outcome measure was the change in best corrected visual acuity at 24 months. Secondary efficacy measures included changes in area of GA, contrast sensitivity, microperimetry measurements, and total drusen area from baseline. Study drug was well tolerated and was associated with few adverse events. The mean change in BCVA at 2 years was +0.2 ± 13.3 letters in the study eyes and -11.3 ± 7.6 letters in fellow eyes (P = 0.0259). However, no statistically significant differences were found between the study and fellow eyes for all other secondary outcome measures. OT-551 was well tolerated by study participants and was not associated with any serious adverse effects. Efficacy measurements in this small study indicate a possible effect in maintaining visual acuity. However, the absence of significant effects on other outcomes measures in this study suggests that OT-551, in the current concentration and mode of delivery, may have limited or no benefit as a treatment for GA (ClinicalTrials.gov number, NCT00306488).

  10. The R package otu2ot for implementing the entropy decomposition of nucleotide variation in sequence data

    Alban eRamette

    2014-11-01

    Full Text Available Oligotyping is a novel, supervised computational method that classifies closely related sequences into oligotypes (OTs based on subtle nucleotide variations (Eren et al. 2013. Its application to microbial datasets has helped reveal ecological patterns which are often hidden by the way sequence data are currently clustered to define operational taxonomic units (OTUs. Here, we implemented the OT entropy decomposition procedure and its unsupervised version, Minimal Entropy Decomposition (MED; Eren et al. 2014, in the statistical programming language and environment, R. The aims are to facilitate the integration of computational routines, interactive statistical analyses, and visualization into a single framework. In addition, two complementary approaches are implemented: 1 An analytical method (the broken stick model is proposed to help identify oligotypes of low abundance that could be generated by chance alone and 2 a one-pass profiling (OP method, to efficiently identify those OTUs whose subsequent oligotyping would be most promising. These enhancements are especially useful for large datasets, where a manual screening of entropy analysis results and the creation of a full set of OTs may not be feasible. The package and procedures are illustrated by several tutorials and examples.

  11. Transcriptional role of androgen receptor in the expression of long non-coding RNA Sox2OT in neurogenesis.

    Valentina Tosetti

    Full Text Available The complex architecture of adult brain derives from tightly regulated migration and differentiation of precursor cells generated during embryonic neurogenesis. Changes at transcriptional level of genes that regulate migration and differentiation may lead to neurodevelopmental disorders. Androgen receptor (AR is a transcription factor that is already expressed during early embryonic days. However, AR role in the regulation of gene expression at early embryonic stage is yet to be determinate. Long non-coding RNA (lncRNA Sox2 overlapping transcript (Sox2OT plays a crucial role in gene expression control during development but its transcriptional regulation is still to be clearly defined. Here, using Bicalutamide in order to pharmacologically inactivated AR, we investigated whether AR participates in the regulation of the transcription of the lncRNASox2OTat early embryonic stage. We identified a new DNA binding region upstream of Sox2 locus containing three androgen response elements (ARE, and found that AR binds such a sequence in embryonic neural stem cells and in mouse embryonic brain. Our data suggest that through this binding, AR can promote the RNA polymerase II dependent transcription of Sox2OT. Our findings also suggest that AR participates in embryonic neurogenesis through transcriptional control of the long non-coding RNA Sox2OT.

  12. VizieR Online Data Catalog: Follow-up photometry of M101 OT2015-1 (Blagorodnova+, 2017)

    Blagorodnova, N.; Kotak, R.; Polshaw, J.; Kasliwal, M. M.; Cao, Y.; Cody, A. M.; Doran, G. B.; Elias-Rosa, N.; Fraser, M.; Fremling, C.; Gonzalez-Fernandez, C.; Harmanen, J.; Jencson, J.; Kankare, E.; Kudritzki, R.-P.; Kulkarni, S. R.; Magnier, E.; Manulis, I.; Masci, F. J.; Mattila, S.; Nugent, P.; Ochner, P.; Pastorello, A.; Reynolds, T.; Smith, K.; Sollerman, J.; Taddia, F.; Terreran, G.; Tomasella, L.; Turatto, M.; Vreeswijk, P. M.; Wozniak, P.; Zaggia, S.

    2017-07-01

    The location of M101-OT2015-1 has been serendipitously imaged by numerous telescopes and instruments over the last 15 years (from 2000 to 2015). Our best quality pre-discovery image (seeing of 0.55") is an r-band exposure at -3625 days pre-peak from the Canada-France-Hawaii Telescope (CFHT). The historical optical data for M101-OT was retrieved from the CFHT MegaPrime and CFHT12K/Mosaic, using single and combined exposures, Pan-STARRS-1/GPC1 (PS1), Isaac Newton Telescope/Wide Field Camera (INT/WFC), and Sloan Digital Sky Survey (SDSS) DR 10 (Ahn+ 2014, see V/147). Unfortunately, there are no HST images covering the location of the source. Post-discovery optical magnitudes were obtained from the reported followup astronomer's telegrams (ATels), Liverpool Telescope (LT), the Nordic Optical Telescope (NOT), and the Palomar P48 and P60 telescopes. The infrared data were retrieved from CFHT/WIRCam, UKIRT/WFCAM, and the Spitzer Infrared Array Camera in 3.6 and 4.5um as part of the SPitzer InfraRed Intensive Transients Survey (SPIRITS) (Kasliwal+, 2017ApJ...839...88K). Details of pre-discovery photometry and post-discovery optical photometry may be found in the Appendices Tables 1 and 2, respectively. We obtained spectra of M101-OT using a range of facilities in 2015 Feb-Jul. (3 data files).

  13. Transcriptional analysis and molecular dynamics simulations reveal the mechanism of toxic metals removal and efflux pumps in Lysinibacillus sphaericus OT4b.31

    Shaw, Dario Rangel; Dussan, Jenny

    2017-01-01

    Lysinibacillus sphaericus strain OT4b.31 is a bacterium widely applied in bioremediation processes of hydrocarbon and metal polluted environments. In this study, we identified the molecular mechanism underlying the Pb2+ and Cr6+ resistance. Metal

  14. Multiseasonal Tree Crown Structure Mapping with Point Clouds from OTS Quadrocopter Systems

    Hese, S.; Behrendt, F.

    2017-08-01

    OTF (Off The Shelf) quadro copter systems provide a cost effective (below 2000 Euro), flexible and mobile platform for high resolution point cloud mapping. Various studies showed the full potential of these small and flexible platforms. Especially in very tight and complex 3D environments the automatic obstacle avoidance, low copter weight, long flight times and precise maneuvering are important advantages of these small OTS systems in comparison with larger octocopter systems. This study examines the potential of the DJI Phantom 4 pro series and the Phantom 3A series for within-stand and forest tree crown 3D point cloud mapping using both within stand oblique imaging in different altitude levels and data captured from a nadir perspective. On a test site in Brandenburg/Germany a beach crown was selected and measured with 3 different altitude levels in Point Of Interest (POI) mode with oblique data capturing and deriving one nadir mosaic created with 85/85 % overlap using Drone Deploy automatic mapping software. Three different flight campaigns were performed, one in September 2016 (leaf-on), one in March 2017 (leaf-off) and one in May 2017 (leaf-on) to derive point clouds from different crown structure and phenological situations - covering the leaf-on and leafoff status of the tree crown. After height correction, the point clouds where used with GPS geo referencing to calculate voxel based densities on 50 × 10 × 10 cm voxel definitions using a topological network of chessboard image objects in 0,5 m height steps in an object based image processing environment. Comparison between leaf-off and leaf-on status was done on volume pixel definitions comparing the attributed point densities per volume and plotting the resulting values as a function of distance to the crown center. In the leaf-off status SFM (structure from motion) algorithms clearly identified the central stem and also secondary branch systems. While the penetration into the crown

  15. MULTISEASONAL TREE CROWN STRUCTURE MAPPING WITH POINT CLOUDS FROM OTS QUADROCOPTER SYSTEMS

    S. Hese

    2017-08-01

    Full Text Available OTF (Off The Shelf quadro copter systems provide a cost effective (below 2000 Euro, flexible and mobile platform for high resolution point cloud mapping. Various studies showed the full potential of these small and flexible platforms. Especially in very tight and complex 3D environments the automatic obstacle avoidance, low copter weight, long flight times and precise maneuvering are important advantages of these small OTS systems in comparison with larger octocopter systems. This study examines the potential of the DJI Phantom 4 pro series and the Phantom 3A series for within-stand and forest tree crown 3D point cloud mapping using both within stand oblique imaging in different altitude levels and data captured from a nadir perspective. On a test site in Brandenburg/Germany a beach crown was selected and measured with 3 different altitude levels in Point Of Interest (POI mode with oblique data capturing and deriving one nadir mosaic created with 85/85 % overlap using Drone Deploy automatic mapping software. Three different flight campaigns were performed, one in September 2016 (leaf-on, one in March 2017 (leaf-off and one in May 2017 (leaf-on to derive point clouds from different crown structure and phenological situations – covering the leaf-on and leafoff status of the tree crown. After height correction, the point clouds where used with GPS geo referencing to calculate voxel based densities on 50 × 10 × 10 cm voxel definitions using a topological network of chessboard image objects in 0,5 m height steps in an object based image processing environment. Comparison between leaf-off and leaf-on status was done on volume pixel definitions comparing the attributed point densities per volume and plotting the resulting values as a function of distance to the crown center. In the leaf-off status SFM (structure from motion algorithms clearly identified the central stem and also secondary branch systems. While the penetration into the

  16. Farmakoterapia zaburzeń behawioralnych towarzyszących otępieniu

    Tomasz Sobów

    2013-12-01

    Full Text Available Farmakoterapia zaburzeń zachowania i objawów neuropsychiatrycznych u chorych otępiałych (behavioural and psychological symptoms of dementia, BPSD była przedmiotem wielu badań klinicznych. Ich wyniki nie pozwalają niestety na sformułowanie prostych zaleceń. Leki przeciwpsychotyczne (zwłaszcza II generacji okazały się względnie skuteczne w zwalczaniu pobudzenia i agresji, ale ich działanie na objawy psychotyczne jest wątpliwe. Poważne obawy dotyczące bezpieczeństwa stosowania leków przeciwpsychotycznych (zwłaszcza ryzyko ostrych zdarzeń sercowo-mózgowych i związanej z nimi śmiertelności w znaczący sposób ograniczają ich wykorzystanie. Leki przeciwdepresyjne, szczególnie z grupy selektywnych inhibitorów zwrotnego wychwytu serotoniny (selective serotonin reuptake inhibitor, SSRI, wykazują podobną skuteczność w zwalczaniu pobudzenia i objawów psychotycznych jak leki przeciwpsychotyczne, co wobec lepszej tolerancji zachęca do ich szerszego stosowania. Inne grupy leków (w tym przeciwdrgawkowe i benzodiazepiny, pomimo teoretycznych przesłanek sugerujących możliwą skuteczność, w randomizowanych badaniach nie zostały ocenione jako wystarczająco efektywne (i bezpieczne, aby rekomendować ich szersze wykorzystanie. Rutynowe stosowanie zasady hierarchicznego postępowania w BPSD (najpierw staranna diagnostyka, w tym wykluczenie majaczenia, następnie interwencje niefarmakologiczne i optymalizacja leczenia inhibitorami cholinesterazy i/lub memantyną, a dopiero w trzeciej kolejności zastosowanie leków psychotropowych pozwala na ograniczenie farmakoterapii w tej szczególnie wrażliwej grupie pacjentów.

  17. Emprego da azida sódica, como conservador de fezes, para a pesquisa de ovos de Schistosoma mansoni e de outros helmintos, pelo método de Kato-Katz: estudo em área endêmica

    Vicente Amato Neto

    1992-09-01

    Full Text Available Em duas alíquotas de 208 amostras de fezes foram feitos exames pelo método de Kato-Katz, sendo uma após o emprego de 0,2mg de azida sódica para 200mg e em outra sem o referido conservador. Os resultados percentuais com e sem conservador foram, respectivamente, para os Ancilostomídeos 12,5 e 25,9, para Ascaris lumbricoides 71,6 e 72,5, para Schistosoma mansoni 7,6 e 17,7 e para Trichuris trichiura 86 e 85. A contagem dos ovos com e sem o conservador foi, respectivamente, 264 e 539 para os Ancilostomídeos, 13816 e 33751 para A. lumbricoides, 55,5 e 63,5 para S. mansoni e 1345 e 2068 para T. trichiura. Os autores não confirmaram a vantagem do uso de azida sódica para estudo em áreas endêmicas. Sugerem que o ressecamento das fezes e a baixa intensidade das infecções possam explicar os resultados desfavoráveis do presente ensaio clínico.In two aliquots of 208 samples of stool, tests have been made by the Kato-Katz method, one being made after the use of 0.2mg of sodic azide for 200mg, and the other without the aforesaid conservant. The resulted percentages with or without the conservant were, respectively, for Ancylostomideos: 12.5 and 25.9; for Ascaris lumbrieoides; 71.6 and 72.5; for Schistosoma mansoni: 7.6 and 17.7, and for Trichuris trichiura: 86 and 85. The count of the eggs with and without the conservant was, respectively, 264 and 539 for Ancylostomideos, 13186 and 33751 for A. lumbricoides, 55.5 and 63.5 for S. mansoni, and 1345 and 2068 for T. trichiura. The authors did not confirm the advantage of using sodic azide for study in endemic areas. They suggest that the exsiccation of the stool and the low intensity of infections can explain the unfavourable results of the present clinical trial.

  18. Comparación de las técnicas Kato-Katz, TSET y TSR en el diagnóstico de infección por Fasciola hepatica en humanos

    Nelson Uribe Delgado

    2012-12-01

    Full Text Available Introducción: La Fasciolosis es una enfermedad causada por el parásito Fasciola hepatica, que afecta primordialmente a bovinos, ovinos, caprinos y en algunas zonas de forma endémica a los humanos. En la investigación clínica y epidemiológica de fasciolosis humana es importante contar con técnicas coprológicas de diagnóstico de alta sensibilidad y especificidad. Objetivo: realizar la comparación de tres técnicas coprológicas para el diagnóstico de infección por Fasciola hepatica en humanos. Metodología: se procesaron 200 gramos de materia fecal de humanos contaminada experimentalmente con huevos de F. hepatica que se obtuvieron de análisis anteriores con muestras de ganado bovino y ovino. La muestra se dividió en 10 partes iguales; a cada una de estas muestras se les realizó la técnicas de Kato-Katz, técnica de sedimentación espontánea en tubo (TSET y técnica de sedimentación rápida (TSR. Finalmente, la lectura de las muestras se basó en el diseño metodológico del doble ciego. Resultados: se encontró que la técnica de sedimentación rápida fue la más sensible de las tres evaluadas, detectándose positividad en 7,5 muestras de 10 analizadas; seguida por la técnica de Kato-Katz con 4,5 muestras y en último lugar la técnica de sedimentación espontánea en Tubo que mostró solo un resultado positivo. Conclusión: en este trabajo se encontró que la técnica de sedimentación rápida constituye la herramienta de elección para el profesional porque es la más sensible de las tres; además de ser sencilla, económica y de fácil aplicación en laboratorios de niveles uno y dos de complejidad para realizar un diagnóstico satisfactorio de fasciolosis humana. Salud UIS 2012; 44 (3: 7-12

  19. Characterization of the archaeal ribonuclease P proteins from Pyrococcus horikoshii OT3.

    Terada, Atsushi; Honda, Takashi; Fukuhara, Hideo; Hada, Kazumasa; Kimura, Makoto

    2006-08-01

    Ribonuclease P (RNase P) is a ribonucleoprotein complex involved in the processing of the 5'-leader sequence of precursor tRNA (pre-tRNA). Our earlier study revealed that RNase P RNA (pRNA) and five proteins (PhoPop5, PhoRpp38, PhoRpp21, PhoRpp29, and PhoRpp30) in the hyperthermophilic archaeon Pyrococcus horikoshii OT3 reconstituted RNase P activity that exhibits enzymatic properties like those of the authentic enzyme. In present study, we investigated involvement of the individual proteins in RNase P activity. Two particles (R-3Ps), in which pRNA was mixed with three proteins, PhoPop5, PhoRpp30, and PhoRpp38 or PhoPop5, PhoRpp30, and PhoRpp21 showed a detectable RNase P activity, and five reconstituted particles (R-4Ps) composed of pRNA and four proteins exhibited RNase P activity, albeit at reduced level compared to that of the reconstituted particle (R-5P) composed of pRNA and five proteins. Time-course analysis of the RNase P activities of R-4Ps indicated that the R-4Ps lacking PhoPop5, PhoRpp21, or PhoRpp30 had virtually reduced activity, while omission of PhoRpp29 or PhoRpp38 had a slight effect on the activity. The results indicate that the proteins contribute to RNase P activity in order of PhoPop5 > PhoRpp30 > PhoRpp21 > PhoRpp29 > PhoRpp38. It was further found that R-4Ps showed a characteristic Mg2+ ion dependency approximately identical to that of R-5P. However, R-4Ps had optimum temperature of around at 55 degrees C which is lower than 70 degrees C for R-5P. Together, it is suggested that the P. horikoshii RNase P proteins are predominantly involved in optimization of the pRNA conformation, though they are individually dispensable for RNase P activity in vitro.

  20. Leczenie otępienia przy współistniejących schorzeniach internistycznych – wybrane zagadnienia

    Alicja Klich-Rączka

    2012-12-01

    Full Text Available Celem poniższej pracy było przedstawienie dylematów związanych ze stosowaniem leków poprawiających funkcje poznawcze przy obecności innych schorzeń u ludzi starszych. Ze względu na powszechną w starości polipatologię otępienie, będące jednym z najistotniejszych problemów medycznych w tym okresie życia, rzadko występuje jako pojedyncze schorzenie – zwykle współistnieje z innymi chorobami. Leczenie otępienia jest zwykle połączone z terapią innych jednostek chorobowych, co wiąże się ze zwiększonym ryzykiem interakcji lekowych oraz działań niepożądanych. Dodatkowo ryzyko tych działań wzrasta z powodu zmian w farmakokinetyce wynikających z gorszej dystrybucji leków w organizmie oraz pogarszającej się z wiekiem wydolności wielonarządowej, czego konsekwencją może być upośledzony metabolizm i wydalanie leków. Spośród stosowanych w leczeniu otępienia inhibitorów acetylocholinesterazy interakcje najczęściej dotyczą donepezilu, co spowodowane jest jego metabolizmem w wątrobie przy udziale cytochromu P450, który równocześnie uczestniczy w metabolizmie wielu innych leków wykorzystywanych w terapii różnych schorzeń wieku starczego. Przeciwwskazaniami do stosowania inhibitorów acetylocholinesterazy są przede wszystkim: ciężka niewydolność wątroby, zespół chorego węzła zatokowego, zaburzenia rytmu i przewodnictwa, czynna choroba wrzodowa żołądka lub dwunastnicy, choroby powodujące utrudnienie odpływu moczu, napady drgawkowe, astma oskrzelowa/przewlekła obturacyjna choroba płuc. Działania niepożądane leków występują u kilku do kilkudziesięciu procent pacjentów, a u części z nich stanowią przeciwwskazania do kontynuowania terapii. Problem interakcji lekowych i działań niepożądanych jest często marginalizowany w leczeniu starszych pacjentów z otępieniem.

  1. Návrh systému regulace vrtule stálých otáček

    Líška, Lukáš

    2014-01-01

    Diplomová práca sa zaoberá problematikou návrhu elektrickej regulácie vrtule konštantných otáčok. Cieľom práce je ukázať postup návrhu regulátora na príklade vrtule DMP-3 pracujúcej s motorom Rotax 912 ULS, využitím vedomostí z mechaniky letu, elektrotechniky a automatizácie. V rámci práce bude poukázané na problematiku riadenia uhla nastavenia vrtule za použitia elektricky riadeného lineárneho aktuátora. Záver práce tvorí porovnanie výhod vrtule konštantných otáčok DMP-3 uvážením jej použiti...

  2. Overexpression, purification, crystallization and preliminary crystallographic studies of a hyperthermophilic adenylosuccinate synthetase from Pyrococcus horikoshii OT3

    Wang, Xiaoying; Akasaka, Ryogo; Takemoto, Chie; Morita, Satoshi; Yamaguchi, Machiko; Terada, Takaho; Shirozu, Mikako; Yokoyama, Shigeyuki; Chen, Shilin; Si, Shuyi; Xie, Yong

    2011-01-01

    A hyperthermophilic adenylosuccinate synthetase from P. horikoshii OT3, which is 90–120 amino acids shorter than those from the vast majority of organisms, was expressed, purified and crystallized and X-ray diffraction data were collected to 2.5 Å resolution. Adenylosuccinate synthetase (AdSS) is a ubiquitous enzyme that catalyzes the first committed step in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP) in the purine-biosynthetic pathway. Although AdSS from the vast majority of organisms is 430–457 amino acids in length, AdSS sequences isolated from thermophilic archaea are 90–120 amino acids shorter. In this study, crystallographic studies of a short AdSS sequence from Pyrococcus horikoshii OT3 (PhAdSS) were performed in order to reveal the unusual structure of AdSS from thermophilic archaea. Crystals of PhAdSS were obtained by the microbatch-under-oil method and X-ray diffraction data were collected to 2.50 Å resolution. The crystal belonged to the trigonal space group P3 2 12, with unit-cell parameters a = b = 57.2, c = 107.9 Å. There was one molecule per asymmetric unit, giving a Matthews coefficient of 2.17 Å 3 Da −1 and an approximate solvent content of 43%. In contrast, the results of native polyacrylamide gel electrophoresis and analytical ultracentrifugation showed that the recombinant PhAdSS formed a dimer in solution

  3. Caracterización de la comunidad de macroinvertebrados de la Quebrada Paloblanco de la Cuenca del Río Otún (Risaralda, Colombia)

    Eleonora Bernal Pinilla; Duberney García García; Miguel Adriano Novoa Bravo; Atticus Pinzón Rodríguez

    2006-01-01

    Se realizó un estudio de las comunidades de macroinvertebrados presentes en la quebrada Paloblanco, ubicada en la cuenca del río Otún (Risaralda, Colombia). Los puntos de muestreo seleccionados corresponden a la cabecera y la zona cercana a la desembocadura en el río Otún, ambos con características geomorfológicas de corrientes de primer orden. En cada punto se colectaron los macroinvertebrados de las unidades funcionales hojarasca, epiliton, musgo y grava, junto con una muestra de deriva y f...

  4. Conservation of Repeats at the Mammalian KCNQ1OT1-CDKN1C Region Suggests a Role in Genomic Imprinting

    Marcos De Donato

    2017-06-01

    Full Text Available KCNQ1OT1 is located in the region with the highest number of genes showing genomic imprinting, but the mechanisms controlling the genes under its influence have not been fully elucidated. Therefore, we conducted a comparative analysis of the KCNQ1/KCNQ1OT1-CDKN1C region to study its conservation across the best assembled eutherian mammalian genomes sequenced to date and analyzed potential elements that may be implicated in the control of genomic imprinting in this region. The genomic features in these regions from human, mouse, cattle, and dog show a higher number of genes and CpG islands (detected using cpgplot from EMBOSS, but lower number of repetitive elements (including short interspersed nuclear elements and long interspersed nuclear elements, compared with their whole chromosomes (detected by RepeatMasker. The KCNQ1OT1-CDKN1C region contains the highest number of conserved noncoding sequences (CNS among mammals, where we found 16 regions containing about 38 different highly conserved repetitive elements (using mVista, such as LINE1 elements: L1M4, L1MB7, HAL1, L1M4a, L1Med, and an LTR element: MLT1H. From these elements, we found 74 CNS showing high sequence identity (>70% between human, cattle, and mouse, from which we identified 13 motifs (using Multiple Em for Motif Elicitation/Motif Alignment and Search Tool with a significant probability of occurrence, 3 of which were the most frequent and were used to find transcription factor–binding sites. We detected several transcription factors (using JASPAR suite from the families SOX, FOX, and GATA. A phylogenetic analysis of these CNS from human, marmoset, mouse, rat, cattle, dog, horse, and elephant shows branches with high levels of support and very similar phylogenetic relationships among these groups, confirming previous reports. Our results suggest that functional DNA elements identified by comparative genomics in a region densely populated with imprinted mammalian genes may be

  5. Pressure effects on enzyme reactions in mainly organic media: alpha-chymotrypsin in reversed micelles of Aerosol OT in octane.

    Mozhaev, V V; Bec, N; Balny, C

    1994-08-01

    Biocatalytic transformations in reversed micelles formed by anionic surfactant Aerosol OT in octane have been studied at high pressures by an example of alpha-chymotrypsin-catalyzed hydrolysis of N-carbobenzoxy-L-tyrosine p-nitrophenyl ester and N-succinyl-L-phenylalanine p-nitroanilide. For the first time it has been found that the enzyme retains high activity in these water-in-oil microemulsions up to a pressure of 2 kbar. The value of the activation volume (delta V*) for the enzyme reactions shows a dependence on the water content in the system. When the size of the micellar aqueous inner cavity (as evaluated at 1 atm) approaches the molecular size of alpha-chymotrypsin, delta V* becomes significantly different from the value in aqueous solution and in the micelles with a larger size. Possibilities of regulating the enzyme activity by pressure in systems with a low content of water are discussed.

  6. A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region.

    Liu, Xiaohua; Kelsoe, John R; Greenwood, Tiffany A

    2016-01-01

    Bipolar disorder is a heterogeneous mood disorder associated with several important clinical comorbidities, such as eating disorders. This clinical heterogeneity complicates the identification of genetic variants contributing to bipolar susceptibility. Here we investigate comorbidity of eating disorders as a subphenotype of bipolar disorder to identify genetic variation that is common and unique to both disorders. We performed a genome-wide association analysis contrasting 184 bipolar subjects with eating disorder comorbidity against both 1370 controls and 2006 subjects with bipolar disorder only from the Bipolar Genome Study (BiGS). The most significant genome-wide finding was observed bipolar with comorbid eating disorder vs. controls within SOX2-OT (p=8.9×10(-8) for rs4854912) with a secondary peak in the adjacent FXR1 gene (p=1.2×10(-6) for rs1805576) on chromosome 3q26.33. This region was also the most prominent finding in the case-only analysis (p=3.5×10(-7) and 4.3×10(-6), respectively). Several regions of interest containing genes involved in neurodevelopment and neuroprotection processes were also identified. While our primary finding did not quite reach genome-wide significance, likely due to the relatively limited sample size, these results can be viewed as a replication of a recent study of eating disorders in a large cohort. These findings replicate the prior association of SOX2-OT with eating disorders and broadly support the involvement of neurodevelopmental/neuroprotective mechanisms in the pathophysiology of both disorders. They further suggest that different clinical manifestations of bipolar disorder may reflect differential genetic contributions and argue for the utility of clinical subphenotypes in identifying additional molecular pathways leading to illness. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Kas ülikoolis õppimine on õige aeg lapse sünnitamiseks? / Ilona Opaal, Liis-Erliken Vinne, Tõnu Ots ... [jt.

    2008-01-01

    Küsimusele vastavad TLÜ anglistikaüliõpilane Ilona Opaal, TLÜ bioloogiaüliõpilane Liis-Erliken Vimme, psühholoog Tõnu Ots, filosoof Valdar Parve, Soome Instituudi direktor Jaana Vasama, psühholoog Tiia Lister, Treffneri Gümnaasiumi usu- ja filosoofiaõpetaja Toomas Jürgenstein

  8. Excretion of radium in relation to dietary intake; Excretion de radium en fonction de l'ingestion alimentaire; Vydelenie radiya v zavisimosti ot priema ego s pishchej; Excrecion de radio en relacion con su absorcion con los alimentos y el agua

    Turner, R. C. [Institute of Cancer Research, Royal Cancer Hospital, London (United Kingdom)

    1963-02-15

    srednej velichiny potrebleniya radiya odnim chelovekom iz ehtikh istochnikov sredi ryada professional'nykh grupp, ravno kak sredi grupp naseleniya razlichnykh rajonov strany. Nesmotrya na shirokij interval velichin aktivnosti produktov pitaniya, srednie velichiny priema malo otlichayutsya drug ot druga u raznykh grupp, pri ehtom oni koleblyutsya mezhdu 2 i 3 mmkkyuri na cheloveka v den'. Soderkhanie radiya v pit'evoj vode v Anglii menyaetsya v diapazone koehffitsientov ot 250 do 1, no v bol'shinstve sluchaev absolyutnye urovni nastol'ko nizki po sravneniyu s urovnem v osnovnykh produktakh pitaniya, chto srednie velichiny potrebleniya radiya s vodoj sostavlyayut lish' 5 - 6% ot srednikh obshchikh kolichestv radiya, pogloshchaemogo kazhdym individuumom. Lish' v odnom rajone strany, v kotorom -prozhivaet men'she odnogo protsenta vsego naseleniya, dnevnoe potreblenie radiya s vodoj prevyshaet potreblenie ego s pishchej. Izmereniya vydelenij s isprazhneniyami v rezul'tate normal'nogo priema pishchi pokazyvaet, chto u vzroslykh molodykh lyudej srednee kolichestvo radiya-226, vydelyaemogo takim putem, sostavlyaet 2-2,5 mmkkyuri v den'. Ehta tsifra soglasuetsya s vychislennymi dannymi srednego dnevnogo priema. Issledovaniya metabolizma u lyudej pokazyvayut, chto bol'shaya chast' sutochnogo kolichestva radiya, prinyatogo s pishchej, vydelyaetsya v techenie 24 - 48 chasov, no popytki opredelit' fraktsionnoe uderzhanie radiya u vzroslykh privodyat k neodinakovym rezul'tatam. Izmereniya velichin dnevnogo priema i vydeleniya s isprazhneniyami u malen'kikh detej v techenie 33 dnej ukazyvayut na to, chto uderzhanie radiya v periody aktivnogo rosta kostej mozhet sostavlyat' do 10% ili bolee ot obshchego kolichestva radiya, prinyatogo vnutr'. (author)

  9. Comparison of a new multiplex real-time PCR with the Kato Katz thick smear and copro-antigen ELISA for the detection and differentiation of Taenia spp. in human stools.

    Ng-Nguyen, Dinh; Stevenson, Mark A; Dorny, Pierre; Gabriël, Sarah; Vo, Tinh Van; Nguyen, Van-Anh Thi; Phan, Trong Van; Hii, Sze Fui; Traub, Rebecca J

    2017-07-01

    Taenia solium, the cause of neurocysticercosis (NCC), has significant socioeconomic impacts on communities in developing countries. This disease, along with taeniasis is estimated to infect 2.5 to 5 million people globally. Control of T. solium NCC necessitates accurate diagnosis and treatment of T. solium taeniasis carriers. In areas where all three species of Taenia tapeworms (T. solium, Taenia saginata and Taenia asiatica) occur sympatrically, conventional microscope- and copro-antigen based diagnostic methods are unable to distinguish between these three Taenia species. Molecular diagnostic tools have been developed to overcome this limitation; however, conventional PCR-based techniques remain unsuitable for large-scale deployment in community-based surveys. Moreover, a real-time PCR (qPCR) for the discrimination of all three species of Taenia in human stool does not exist. This study describes the development and validation of a new triplex Taq-Man probe-based qPCR for the detection and discrimination of all three Taenia human tapeworms in human stools collected from communities in the Central Highlands of Vietnam. The diagnostic characteristics of the test are compared with conventional Kato Katz (KK) thick smear and copro-antigen ELISA (cAgELISA) method utilizing fecal samples from a community based cross-sectional study. Using this new multiplex real-time PCR we provide an estimate of the true prevalence of taeniasis in the source population for the community based cross-sectional study. Primers and TaqMan probes for the specific amplification of T. solium, T. saginata and T. asiatica were designed and successfully optimized to target the internal transcribed spacer I (ITS-1) gene of T. solium and the cytochrome oxidase subunit I (COX-1) gene of T. saginata and T. asiatica. The newly designed triplex qPCR (T3qPCR) was compared to KK and cAgELISA for the detection of Taenia eggs in stool samples collected from 342 individuals in Dak Lak province, Central

  10. Comparison of a new multiplex real-time PCR with the Kato Katz thick smear and copro-antigen ELISA for the detection and differentiation of Taenia spp. in human stools.

    Dinh Ng-Nguyen

    2017-07-01

    Full Text Available Taenia solium, the cause of neurocysticercosis (NCC, has significant socioeconomic impacts on communities in developing countries. This disease, along with taeniasis is estimated to infect 2.5 to 5 million people globally. Control of T. solium NCC necessitates accurate diagnosis and treatment of T. solium taeniasis carriers. In areas where all three species of Taenia tapeworms (T. solium, Taenia saginata and Taenia asiatica occur sympatrically, conventional microscope- and copro-antigen based diagnostic methods are unable to distinguish between these three Taenia species. Molecular diagnostic tools have been developed to overcome this limitation; however, conventional PCR-based techniques remain unsuitable for large-scale deployment in community-based surveys. Moreover, a real-time PCR (qPCR for the discrimination of all three species of Taenia in human stool does not exist. This study describes the development and validation of a new triplex Taq-Man probe-based qPCR for the detection and discrimination of all three Taenia human tapeworms in human stools collected from communities in the Central Highlands of Vietnam. The diagnostic characteristics of the test are compared with conventional Kato Katz (KK thick smear and copro-antigen ELISA (cAgELISA method utilizing fecal samples from a community based cross-sectional study. Using this new multiplex real-time PCR we provide an estimate of the true prevalence of taeniasis in the source population for the community based cross-sectional study.Primers and TaqMan probes for the specific amplification of T. solium, T. saginata and T. asiatica were designed and successfully optimized to target the internal transcribed spacer I (ITS-1 gene of T. solium and the cytochrome oxidase subunit I (COX-1 gene of T. saginata and T. asiatica. The newly designed triplex qPCR (T3qPCR was compared to KK and cAgELISA for the detection of Taenia eggs in stool samples collected from 342 individuals in Dak Lak province

  11. Comparison of a new multiplex real-time PCR with the Kato Katz thick smear and copro-antigen ELISA for the detection and differentiation of Taenia spp. in human stools

    Stevenson, Mark A.; Dorny, Pierre; Gabriël, Sarah; Vo, Tinh Van; Nguyen, Van-Anh Thi; Phan, Trong Van; Hii, Sze Fui; Traub, Rebecca J.

    2017-01-01

    Background Taenia solium, the cause of neurocysticercosis (NCC), has significant socioeconomic impacts on communities in developing countries. This disease, along with taeniasis is estimated to infect 2.5 to 5 million people globally. Control of T. solium NCC necessitates accurate diagnosis and treatment of T. solium taeniasis carriers. In areas where all three species of Taenia tapeworms (T. solium, Taenia saginata and Taenia asiatica) occur sympatrically, conventional microscope- and copro-antigen based diagnostic methods are unable to distinguish between these three Taenia species. Molecular diagnostic tools have been developed to overcome this limitation; however, conventional PCR-based techniques remain unsuitable for large-scale deployment in community-based surveys. Moreover, a real-time PCR (qPCR) for the discrimination of all three species of Taenia in human stool does not exist. This study describes the development and validation of a new triplex Taq-Man probe-based qPCR for the detection and discrimination of all three Taenia human tapeworms in human stools collected from communities in the Central Highlands of Vietnam. The diagnostic characteristics of the test are compared with conventional Kato Katz (KK) thick smear and copro-antigen ELISA (cAgELISA) method utilizing fecal samples from a community based cross-sectional study. Using this new multiplex real-time PCR we provide an estimate of the true prevalence of taeniasis in the source population for the community based cross-sectional study. Methodology/Principal findings Primers and TaqMan probes for the specific amplification of T. solium, T. saginata and T. asiatica were designed and successfully optimized to target the internal transcribed spacer I (ITS-1) gene of T. solium and the cytochrome oxidase subunit I (COX-1) gene of T. saginata and T. asiatica. The newly designed triplex qPCR (T3qPCR) was compared to KK and cAgELISA for the detection of Taenia eggs in stool samples collected from 342

  12. Databáze a generování testovacích otázek

    Rejko, Peter

    2008-01-01

    Cílem bakalářské práce je vytvoření databáze testovacích otázek a jejich generování. Je rozdělená na teoretickou a praktickou část. V teoretické jsou popsané nástroje se zaměřením na tvorbu databází jazyku HTML, PHP a databázový server MySQL. Praktická část obsahuje vytvořenou aplikaci a zpracování. Jazyk PHP podporuje programování na základě modulárního paradigmatu - to znamená, že každý vytvořený modul má svoji úlohu. Aplikace obsahuje modul zabezpečující přihlášení a výběr dalšího modulu n...

  13. Crystallization and preliminary X-ray analysis of PH1010 from Pyrococcus horikoshii OT3, a member of the archaeal DUF54 family of proteins

    Shirokane, Michio; Sawano, Yoriko; Miyazono, Ken-ichi; Nagata, Koji; Tanokura, Masaru

    2007-01-01

    PH1010, a DUF54-family protein from the hyperthermophilic archaeon P. horikoshii OT3, was crystallized and X-ray diffraction data were collected to 1.90 Å resolution. PH1010 from Pyrococcus horikoshii OT3, a member of the archaeal DUF54 family of proteins, was expressed, purified and crystallized. Crystallization was performed by the sitting-drop vapour-diffusion method using PEG 3350 as the precipitant. The crystal diffracted X-rays to 1.90 Å resolution using a synchrotron-radiation source. The space group of the crystal was determined to be P2 1 2 1 2 1 , with unit-cell parameters a = 46.9, b = 49.5, c = 132.7 Å. The crystal contained two PH1010 molecules in the asymmetric unit (V M = 2.4 Å 3 Da −1 ) and had a solvent content of 48%

  14. Crystallization and preliminary X-ray analysis of PH1010 from Pyrococcus horikoshii OT3, a member of the archaeal DUF54 family of proteins

    Shirokane, Michio; Sawano, Yoriko; Miyazono, Ken-ichi; Nagata, Koji; Tanokura, Masaru, E-mail: amtanok@mail.ecc.u-tokyo.ac.jp [Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657 (Japan)

    2007-06-01

    PH1010, a DUF54-family protein from the hyperthermophilic archaeon P. horikoshii OT3, was crystallized and X-ray diffraction data were collected to 1.90 Å resolution. PH1010 from Pyrococcus horikoshii OT3, a member of the archaeal DUF54 family of proteins, was expressed, purified and crystallized. Crystallization was performed by the sitting-drop vapour-diffusion method using PEG 3350 as the precipitant. The crystal diffracted X-rays to 1.90 Å resolution using a synchrotron-radiation source. The space group of the crystal was determined to be P2{sub 1}2{sub 1}2{sub 1}, with unit-cell parameters a = 46.9, b = 49.5, c = 132.7 Å. The crystal contained two PH1010 molecules in the asymmetric unit (V{sub M} = 2.4 Å{sup 3} Da{sup −1}) and had a solvent content of 48%.

  15. DNA methylation patterns of imprinting centers for H19, SNRPN, and KCNQ1OT1 in single-cell clones of human amniotic fluid mesenchymal stem cell

    Hsiu-Huei Peng

    2012-09-01

    Conclusion: In conclusion, human amniotic fluid mesenchymal stem cells contain a unique epigenetic signature during in vitro cell culture. H19 and KCNQ1OT1 possessed a substantial degree of hypermethylation status, and variable DNA methylation patterns of SNRPN was observed during in vitro cell culture of human amniotic fluid mesenchymal stem cells. Our results urge further understanding of epigenetic status of human amniotic fluid mesenchymal stem cells before it is applied in cell replacement therapy.

  16. Geología de la zona de influencia de la falla otú en el distrito minero segovia-remedios

    MILTON ÁLVAREZ GALINDEZ

    2007-01-01

    Full Text Available Se presenta la caracterización geológica y estructural de la zona de influencia de la falla Otú en jurisdicción del distrito minero Segovia-Remedios. Además, se proponen controles mecánicos para las mineralizaciones auríferas, que si bien son compatibles, en parte, con un modelo de depósitos de oro orogénico, dejan abiertas otras posibles interpretaciones

  17. Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.

    Evelyne Derelle

    Full Text Available Large DNA viruses are ubiquitous, infecting diverse organisms ranging from algae to man, and have probably evolved from an ancient common ancestor. In aquatic environments, such algal viruses control blooms and shape the evolution of biodiversity in phytoplankton, but little is known about their biological functions. We show that Ostreococcus tauri, the smallest known marine photosynthetic eukaryote, whose genome is completely characterized, is a host for large DNA viruses, and present an analysis of the life-cycle and 186,234 bp long linear genome of OtV5. OtV5 is a lytic phycodnavirus which unexpectedly does not degrade its host chromosomes before the host cell bursts. Analysis of its complete genome sequence confirmed that it lacks expected site-specific endonucleases, and revealed the presence of 16 genes whose predicted functions are novel to this group of viruses. OtV5 carries at least one predicted gene whose protein closely resembles its host counterpart and several other host-like sequences, suggesting that horizontal gene transfers between host and viral genomes may occur frequently on an evolutionary scale. Fifty seven percent of the 268 predicted proteins present no similarities with any known protein in Genbank, underlining the wealth of undiscovered biological diversity present in oceanic viruses, which are estimated to harbour 200Mt of carbon.

  18. Choosy but not chaste: multiple mating in human females.

    Scelza, Brooke A

    2013-01-01

    When Charles Darwin set out to relate his theory of evolution by natural selection to humans he discovered that a complementary explanation was needed to properly understand the great variation seen in human behavior. The resulting work, The Descent of Man and Selection in Relation to Sex, laid out the defining principles and evidence of sexual selection. In brief, this work is best known for illuminating the typically male strategy of intrasexual competition and the typically female response of intersexual choice. While these sexual stereotypes were first laid out by Darwin, they grew in importance when, years later, A. J. Bateman, in a careful study of Drosophila mating strategies, noted that multiple mating appeared to provide great benefit to male reproductive success, but to have no such effect on females. As a result, female choice soon became synonymous with being coy, and only males were thought to gain from promiscuous behavior. However, the last thirty years of research have served to question much of the traditional wisdom about sex differences proposed by Darwin and Bateman, illuminating the many ways that women (and females more generally) can and do engage in multiple mating. Copyright © 2013 Wiley Periodicals, Inc.

  19. No Time for Love: Plutarch’s Chaste Caesar

    Jeffrey Beneker

    2006-03-01

    Full Text Available Plutarch’s biography of Julius Caesar, compared with other accounts, deliberately plays down sexuality as a motive in Caesar's life, in order to stress his single-minded political ambition.

  20. Matrjoshki ot kutjur

    2008-01-01

    Vene moeajakirja Vogue kümnendaks juubeliks joonistasid tuntud moekunstnikud kogu maailmast matrjoshkade eskiise. Eskiiside järgi maalisid vene meistrid poolemeetrised nukud. Nii sai ajakiri kingituseks Yves Saint Laurent'i, Versace, Prada, Dolce&Gabbana, Oscar de la Renta, Judashkini, Simatshovi ja paljude teiste matrjoshkad

  1. Purification, crystallization and preliminary X-ray crystallographic analysis of the archaeal phosphoglycerate mutase PH0037 from Pyrococcus horikoshii OT3

    Lokanath, Neratur K.; Kunishima, Naoki, E-mail: kunisima@spring8.or.jp [Advanced Protein Crystallography Research Group, RIKEN SPring-8 Center, Harima Institute, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan)

    2006-08-01

    The archaeal phosphoglycerate mutase PH0037 from P. horikoshii OT3 has been crystallized in space group R32, with unit-cell parameters a = 155.62, c = 230.35 Å. A 2.2 Å resolution data was collected at SPring-8 beamline BL26B1. Phosphoglycerate mutases catalyze the interconversion of 2-phosphoglycerate and 3-phosphoglycerate in glycolysis and gluconeogenesis pathways. The archaeal phosphoglycerate mutase PH0037 from Pyrococcus horikoshii OT3 has been overexpressed in Escherichia coli and purified. Crystals were obtained using the oil-microbatch method at 291 K. A native data set extending to a resolution of 2.2 Å has been collected and processed in space group R32. Assuming the presence of a dimer in the asymmetric unit, the V{sub M} value is calculated to be 3.0 Å{sup 3} Da{sup −1}, consistent with the dynamic light-scattering experiment result, which shows a dimeric state of the protein in solution. Molecular-replacement trials using the crystal structure of Bacilllus stearothermophilus phosphoglycerate mutase as a search model did not provide a satisfactory solution, indicating substantially different structures of these two phophoglycerate mutases.

  2. Purification, crystallization and preliminary X-ray diffraction studies of a putative UDP-N-acetyl-d-mannosamine dehydrogenase from Pyrococcus horikoshii OT3

    Lokanath, Neratur K.; Pampa, Kudigana J.; Kamiya, Toshimi; Kunishima, Naoki, E-mail: kunisima@spring8.or.jp [Advanced Protein Crystallography Research Group, RIKEN SPring-8 Center, Harima Institute, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan)

    2007-05-01

    A putative UDP-N-acetyl-d-mannosamine dehydrogenase from P. horikoshii OT3 has been crystallized in space group P2{sub 1}, with unit-cell parameters a = 80.28, b = 69.24, c = 83.10 Å, β = 114.4°. X-ray diffraction data have been collected to 1.80 Å resolution. A putative UDP-N-acetyl-d-mannosamine dehydrogenase from Pyrococcus horikoshii OT3, an essential enzyme for polysaccharide biosynthesis, has been overexpressed in Escherichia coli and purified. Crystals were obtained using the oil-microbatch method at 291 K. A native data set extending to 1.8 Å resolution has been collected and processed in space group P2{sub 1}. Assuming the presence of a dimer in the asymmetric unit, the V{sub M} value is calculated to be 2.3 Å{sup 3} Da{sup −1}, which is consistent with the result of a dynamic light-scattering experiment that shows a dimeric state of the protein in solution.

  3. Transcriptional analysis and molecular dynamics simulations reveal the mechanism of toxic metals removal and efflux pumps in Lysinibacillus sphaericus OT4b.31

    Shaw, Dario Rangel

    2017-11-23

    Lysinibacillus sphaericus strain OT4b.31 is a bacterium widely applied in bioremediation processes of hydrocarbon and metal polluted environments. In this study, we identified the molecular mechanism underlying the Pb2+ and Cr6+ resistance. Metal uptake and temporal transcription patterns of metal resistance operons were evaluated using reverse-transcribed quantitative PCR amplification. The function of the resistance determinants was studied applying docking and in silico mutagenesis methods. The results revealed that the adaptation of Lysinibacillus sphaericus OT4b.31 to elevated levels of lead and chromium involves the pbr and chr operons which comprise a transcriptional regulatory component (pbrR and chrB) and efflux ATPases (pbrA and chrA) to expel ions from the cytoplasm. Expression of metal resistance genes was constitutive and specifically inducible to the exposure of Pb2+ and Cr6+. The simultaneous presence of cations didn\\'t affect the bioaccumulation of metals, evidencing the multimetal resistance of L. sphaericus. Docking analysis revealed the key metal-protein interactions and the conformational changes after metal or ATP binding. Results showed that residues with aromatic rings or imidazole in the catalytic domain are crucial for metal binding and achievement of the function. To our knowledge, this is the first report of a specific mechanism for lead and chromium resistance in Lysinibacillus genus. From the findings of this study, it is possible to suggest the bacterium as a suitable candidate for rapid toxic metals bioremediation processes.

  4. A Otávia do Pseudo-Sêneca: tradução, estudo introdutório e notas

    Fernanda Vieira Gôzo

    2016-01-01

    Esta pesquisa de mestrado objetivou o estudo da peça latina Otávia do Pseudo-Sêneca, que inclui uma tradução para o português, acompanhada de notas e de um estudo introdutório. Este trabalho centrou-se em apontar o que se têm discutido entre os estudiosos de literatura clássica em relação à peça. Foi pertinente para esse expediente uma análise do gênero praetexta, do qual faz parte esta peça, considerando as divergências entre praetexta republicana e imperial, bem como a observação de como a ...

  5. Caracterización de la comunidad de macroinvertebrados de la Quebrada Paloblanco de la Cuenca del Río Otún (Risaralda, Colombia

    Eleonora Bernal Pinilla

    2006-07-01

    Full Text Available Se realizó un estudio de las comunidades de macroinvertebrados presentes en la quebrada Paloblanco, ubicada en la cuenca del río Otún (Risaralda, Colombia. Los puntos de muestreo seleccionados corresponden a la cabecera y la zona cercana a la desembocadura en el río Otún, ambos con características geomorfológicas de corrientes de primer orden. En cada punto se colectaron los macroinvertebrados de las unidades funcionales hojarasca, epiliton, musgo y grava, junto con una muestra de deriva y fauna general (sin discriminar unidad funcional. Se encontraron 42 familias de Insecta, además de Acari, Annelida, Crustacea e Hirudinea. Igualmente se encontraron familias de presencia exclusiva en cada punto, mostrando diferencias en la composición de las comunidades. Los índices ecológicos empleados mostraron una mayor diversidad en punto bajo y diferencias entre algunas de las unidades funcionales, relacionados con el medio y los hábitos presentes. Para el análisis se tuvieron en cuenta los conceptos de continuo y zonación de los ríos. A pesar de tener condiciones de primer orden, existen variaciones a pequeña escala entre los puntos de muestreo, que están relacionadas con la intervención antrópica en la zona aledaña a punto bajo.

  6. Evaluación de la diversidad de bacterias degradadoras de hidrocarburos aisladas de suelos de las cuencas de los ríos Otún y La Vieja / Evaluation of hydrocarbon degrading bacteria diversity isolated from soils of Otún and La Vieja river basins

    Yanine Suárez, Habib Fernando

    2010-01-01

    Se evaluó el efecto del uso del suelo, sobre la densidad y diversidad de bacterias degradadoras de hidrocarburos (HC). Se seleccionaron los usos: bosque, pastizal y cafetal en la cuenca del río La Vieja (Valle del Cauca y Quindío), y bosque, cebollar y plantación forestal en la cuenca del río Otún (Risaralda) y se realizaron dos eventos de muestreo. La densidad se evaluó mediante la técnica de NMP en medio Bushnell-Hass, suplementado con diesel y usando XTT como indicador de actividad. Las ba...

  7. Resenha de 1976: Movimento Black Rio, de Luiz Felipe de Lima Peixoto e Zé Otávio Sabadelhe (Rio de Janeiro: José Olympio, 2016

    Carlos Palombini

    2017-08-01

    Full Text Available Lançado em 10 de novembro de 2016, o livro 1976: Movimento Black Rio, dos jornalistas Luiz Felipe de Lima Peixoto e Zé Otávio Sabadelhe, celebra os quarenta anos da manchete de Lena Frias, Black Rio: o orgulho (importado de ser negro no Brasil, publicada em 17 de julho de 1976 no Caderno B do Jornal do Brasil. Em 28 reportagens, os autores recorrem a entrevistas e material previamente publicado para contar a história da cultura de bailes que, alimentados por soul, funk e disco afro-norte-americanos, espalharam-se pela Zona Norte carioca nos anos 1970, bem como a história do conjunto das apropriações desses gêneros por Tim Maia, Toni Tornado, Hyldon, Carlos Dafé, Cassiano, Gerson King Combo, Dom Salvador e Abolição, União Black, e Banda Black Rio. O livro tenciona constituir “uma contribuição à construção discursiva de uma memória social positiva da população negra brasileira” e oferece elementos para um trabalho necessário de revisão historiográfica que transcende o âmbito do tema tratado, apesar de erros fatuais que poderiam ter sido corrigidos por cruzamento de dados.

  8. Reversal of hepatorenal syndrome type 1 with terlipressin plus albumin vs. placebo plus albumin in a pooled analysis of the OT-0401 and REVERSE randomised clinical studies.

    Sanyal, A J; Boyer, T D; Frederick, R T; Wong, F; Rossaro, L; Araya, V; Vargas, H E; Reddy, K R; Pappas, S C; Teuber, P; Escalante, S; Jamil, K

    2017-06-01

    The goal of hepatorenal syndrome type 1 (HRS-1) treatment is to improve renal function. Terlipressin, a synthetic vasopressin analogue, is a systemic vasoconstrictor used for the treatment of HRS-1, where it is available. To compare the efficacy of terlipressin plus albumin vs. placebo plus albumin in patients with HRS-1. Pooled patient-level data from two large phase 3, randomised, placebo-controlled studies were analysed for HRS reversal [serum creatinine (SCr) value ≤133 μmol/L], 90-day survival, need for renal replacement therapy and predictors of HRS reversal. Patients received intravenous terlipressin 1-2 mg every 6 hours plus albumin or placebo plus albumin up to 14 days. The pooled analysis comprised 308 patients (terlipressin: n = 153; placebo: n = 155). HRS reversal was significantly more frequent with terlipressin vs. placebo (27% vs. 14%; P = 0.004). Terlipressin was associated with a more significant improvement in renal function from baseline until end of treatment, with a mean between-group difference in SCr concentration of -53.0 μmol/L (P albumin resulted in a significantly higher rate of HRS reversal vs. albumin alone in patients with HRS-1. Terlipressin treatment is associated with improved renal function. (ClinicalTrials.gov identifier: OT-0401, NCT00089570; REVERSE, NCT01143246). © 2017 The Authors. Alimentary Pharmacology and Therapeutics published by John Wiley & Sons Ltd.

  9. Amphibians and Reptiles from Paramakatoi and Kato, Guyana

    MacCulloch, Ross D.; Reynolds, Robert P.

    2012-01-01

    We report the herpetofauna of two neighboring upland locations in west-central Guyana. Twenty amphibian and 24 reptile species were collected. Only 40% of amphibians and 12.5% of reptiles were collected in both locations. This is one of the few collections made at upland (750–800 m) locations in the Guiana Shield.

  10. Hıyarda (Cucumis sativus L. yabancı ot çıkış zamanın tahminine yönelik araştırmalar

    Nihat Tursun

    2015-01-01

    Full Text Available İstatistiki modellerin geliştirilmesi için hıyar bitkisinde on bir önemli yabancı otun çıkış zamanın belirlenmesinde modellemeler yapılmıştır. Hıyar deneme arazisinde bulunan önemli yabancı otlar çıkış zamanlarına göre gruplara ayrılmıştır. Bu yabancı otlardan; Amaranthus retroflexus, Chenopodium album, Heliotropium europaeum, Polygonum aviculare ve Solanum nigrum erken, Convolvulus arvensis, Cyperus rotundus, Cynodon dactylon, Portulaca oleracea ve Sorghum halepense bütün vejetasyon boyunca ve Tribulus terrestris ise geç çimlenen yabancı ot türü olarak belirlenmiştir. Farklı doğrusal olmayan büyüme eğrileri (Chapman-Richard, Weibull, logistic, Gompertz ve cubic spline farklı yabancı ot türleri ve yıllar için çıkış yüzdeleri verileri esas alınarak uyarlanmıştır. Cubic splin model birçok yabancı ot türü için en iyi model olarak saptanmıştır.

  11. Identification of a novel amino acid racemase from a hyperthermophilic archaeon Pyrococcus horikoshii OT-3 induced by D-amino acids.

    Kawakami, Ryushi; Ohmori, Taketo; Sakuraba, Haruhiko; Ohshima, Toshihisa

    2015-08-01

    To date, there have been few reports analyzing the amino acid requirement for growth of hyperthermophilic archaea. We here found that the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 requires Thr, Leu, Val, Phe, Tyr, Trp, His and Arg in the medium for growth, and shows slow growth in medium lacking Met or Ile. This largely corresponds to the presence, or absence, of genes related to amino acid biosynthesis in its genome, though there are exceptions. The amino acid requirements were dramatically lost by addition of D-isomers of Met, Leu, Val, allo-Ile, Phe, Tyr, Trp and Arg. Tracer analysis using (14)C-labeled D-Trp showed that D-Trp in the medium was used as a protein component in the cells, suggesting the presence of D-amino acid metabolic enzymes. Pyridoxal 5'-phosphate (PLP)-dependent racemase activity toward Met, Leu and Phe was detected in crude extract of P. horikoshii and was enhanced in cells grown in the medium supplemented with D-amino acids, especially D-allo-Ile. The gene encoding the racemase was narrowed down to one open reading frame on the basis of enzyme purification from P. horikoshii cells, and the recombinant enzyme exhibited PLP-dependent racemase activity toward several amino acids, including Met, Leu and Phe, but not Pro, Asp or Glu. This is the first report showing the presence in a hyperthermophilic archaeon of a PLP-dependent amino acid racemase with broad substrate specificity that is likely responsible for utilization of D-amino acids for growth.

  12. Crystallization and preliminary X-ray crystallographic studies of the biotin carboxyl carrier protein and biotin protein ligase complex from Pyrococcus horikoshii OT3

    Bagautdinov, Bagautdin; Matsuura, Yoshinori; Bagautdinova, Svetlana; Kunishima, Naoki

    2007-01-01

    A truncated form of biotin carboxyl carrier protein containing the C-terminal half fragment (BCCPΔN76) and the biotin protein ligase (BPL) with the mutation R48A (BPL*) or the double mutation R48A K111A (BPL**) were successfully cocrystallized in the presence of ATP and biotin. The BPL*–BCCPΔN76 and BPL**–BCCPΔN76 crystals belong to space group P2 1 and diffract X-rays to 2.7 and 2.0 Å resolution, respectively. Biotin protein ligase (BPL) catalyses the biotinylation of the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase. To elucidate the exact details of the protein–protein interactions in the biotinylation function, the C-terminal half fragment of BCCP (BCCPΔN76), the R48A mutant of BPL (BPL*) and the R48A K111A double mutant of BPL (BPL**), all of which are from Pyrococcus horikoshii OT3, have been expressed, purified and successfully cocrystallized. Cocrystals of the BPL*–BCCPΔN76 and BPL**–BCCPΔN76 complexes as well as crystals of BPL*, BPL** and BCCPΔN76 were obtained by the oil-microbatch method using PEG 20 000 as a precipitant at 295 K. Complete X-ray diffraction data sets for BPL*–BCCPΔN76 and BPL**–BCCPΔN76 crystals were collected at 100 K to 2.7 and 2.0 Å resolution, respectively, using synchrotron radiation. They belong to the monoclinic space group P2 1 , with similar unit-cell parameters a = 69.85, b = 63.12, c = 75.64 Å, β = 95.9°. Assuming two subunits of the complex per asymmetric unit gives a V M value of 2.45 Å 3 Da −1 and a solvent content of 50%

  13. Samozashtshita ot oruzhija / Ljubov Semjonova

    Semjonova, Ljubov

    2002-01-01

    Andrei Dikarev, Föderatsiooni Aikido president Eestis, leiab, et Eestis on vaja rohkem teadvustada inimestele, mida tähendab isiklik julgeolek. Vt. samas interv. Politseiameti korrakaitseinspektori Vambo Olbergiga eraisikute valduses olevate relvade teemal

  14. Dokazatelstvo ot obratnogo / Lev Livshits

    Лившиц, Лев, 1924-2013

    2008-01-01

    UNESCO maailmapärandi nimekirja kuuluva Tallinna vanalinna kaitsetsooni loomisest ja kõrghoonete ehitamisest vanalinna läheduses. UNESCO komitee nõuab vanalinna puhvertsooni loomise kava ja ülevaadet Tallinna kõrghoonete teemaplaneeringust

  15. 59 Cyg and OT Gem

    2009-07-23

    Jul 23, 2009 ... of the circumstellar disk using the Hα line and also ... the time interval 1978–1987 and saw the V /R variabil- ..... Time series of 59 Cyg Hα line observed in July 2009; (Spectra are offset and labelled with the observation date,.

  16. Zastosowanie jakościowej analizy profilu wykonania skali ACE-III w diagnostyce różnicowej chorób otępiennych

    Emilia J. Sitek

    2017-03-01

    Full Text Available Skala Addenbrooke’s Cognitive Examination III (ACE-III jest poszerzonym narzędziem przesiewowej oceny funkcji poznawczych, użytecznym we wczesnym wykrywaniu zaburzeń poznawczych, wstępnej diagnostyce różnicowej zespołów otępiennych oraz monitorowaniu postępu choroby. ACE-III ocenia uwagę i orientację, pamięć, fluencję słowną, funkcje językowe i wzrokowo-przestrzenne. Skala może być używana przez lekarzy i psychologów, zarówno jako narzędzie przesiewowe, jak i jako wstęp do kompleksowej oceny neuropsychologicznej. ACE-III zawiera również krótsze narzędzie, Mini-ACE, które w razie potrzeby może być stosowane niezależnie. W niniejszej pracy ACE-III porównano z innymi najbardziej popularnymi skalami przesiewowej oceny funkcji poznawczych: Mini-Mental State Examination (MMSE oraz Montrealską Skalą Oceny Funkcji Poznawczych (Montreal Cognitive Assessment, MoCA. Następnie omówiono przydatność kliniczną analizy profilu wykonania ACE-III w  diagnostyce różnicowej wybranych chorób neurozwyrodnieniowych. Zaprezentowano profile wykonania ACE-III typowe dla choroby Alzheimera (zarówno o wczesnym, jak i o późnym początku, zwyrodnienia czołowo-skroniowego, choroby Parkinsona, atypowych zespołów parkinsonowskich oraz otępienia naczyniopochodnego. Spośród atypowych wariantów choroby Alzheimera uwzględniono zanik korowy tylny, wariant logopeniczny afazji pierwotnej postępującej i wariant czołowy. Spośród podstawowych wariantów zwyrodnienia czołowo-skroniowego przedstawiono wariant behawioralny otępienia czołowo- -skroniowego oraz niepłynny i semantyczny wariant afazji pierwotnej postępującej. Wreszcie spośród zespołów parkinsonizm plus omówiono otępienie z ciałami Lewy’ego, zanik wieloukładowy, postępujące porażenie ponadjądrowe i zwyrodnienie korowo-podstawne.

  17. Muusika : Hortus Musicus Moskvas. Eesti Rahvusmeeskoor Toulouse'is. Joaquín Rodrigo 100. Georg Ots kuuel plaadil. "Kiriku laulu- ja palveraamat" ئ 10. "Vikerraadio" heategevuskontsert. Artur Kapi ühingu esimees on Andres Uibo / Vello Mäeots

    Mäeots, Vello, 1940-2015

    2001-01-01

    20. XI esines Hortus Musicus Moskvas Eesti saatkonnas. Eesti Rahvusmeeskoor kandis 15.XI Toulouse'is koos Toulouse'i Rahvusliku Linnaorkestriga ette Jean Sibeliuse "Kullervo". 22.XI tähistatakse hispaania helilooja Joaquín Rodrigo 100. sünniaastapäeva. Estonia teatri Valges saalis esitleti kogumik-CD-d "Georg Ots ئ Anthology". "Kiriku laulu- ja palveraamat" sai 30.XI 10. aastaseks. 3.XII toimub Tallinnas Kaarli kirikus "Vikerraadio" heategevuskontsert "Aita alustada elu". 26.X asutati Suure-Jaanis Rahvusvaheline Artur Kapi Ühing, mille esimeheks valiti organist Andres Uibo

  18. Dinámica de construcción territorial en los asentamientos del río Otún en Pereira (1950- 2000: fenomenología a la territorialidad del sujeto habitante

    Julio César Murillo García

    2016-06-01

    Full Text Available El presente artículo surge como resultado del análisis- interpretación a la dinámica territorial en los asentamientos informales ubicados sobre las márgenes del río Otún a su paso por la comuna Otún en la ciudad de Pereira, desde dos momentos nodales de su construcción: momento fundacional (1950 y momento de toma y apropiación de predios (2000. Como metodología se asume la fenomenología a la territorialidad cotidiana del habitante, explícitamente desde dos variables: contexto socioeconómico y vínculos territoriales. A partir de allí se consolidaron universos de análisis e interpretación sobre la territorialidad del sujeto que dan cuenta de fricciones y/o conflictos espaciales con respecto a la política pública territorial del municipio de Pereira, en medio de la ejecución de programas y proyectos de gestión y planificación territorial con un denotado carácter hegemónico. Con ello se despeja un panorama crítico reflexivo alrededor de la implementación de estas políticas y al desarrollo sostenible territorial.

  19. CD80 and CD86 Costimulatory Molecules Differentially Regulate OT-II CD4+ T Lymphocyte Proliferation and Cytokine Response in Cocultures with Antigen-Presenting Cells Derived from Pregnant and Pseudopregnant Mice

    Tomasz Maj

    2014-01-01

    Full Text Available Immune phenomena during the preimplantation period of pregnancy are poorly understood. The aim of our study was to assess the capacity for antigen presentation of splenic antigen-presenting cells (APCs derived from pregnant and pseudopregnant mice in in vitro conditions. Therefore, sorted CD11c+ dendritic cells and macrophages F4/80+ and CD11b+ presenting ovalbumin (OVA were cocultured with CD4+ T cells derived from OT-II mice’s (C57BL6/J-Tg(TcraTcrb1100Mjb/J spleen. After 132 hours of cell culture, proliferation of lymphocytes (ELISA-BrdU, activation of these cells (flow cytometry, cytokine profile (ELISA, and influence of costimulatory molecules blocking on these parameters were measured. We did not detect any differences in regulation of Th1/Th2 cytokine balance. CD86 seems to be the main costimulatory molecule involved in the proliferation response but CD80 is the main costimulatory molecule influencing cytokine secretion in pregnant mice. In conclusion, this study showed that CD80 and CD86 costimulatory molecules regulate OT-II CD4+ T lymphocyte proliferation and cytokine response in cocultures with antigen-presenting cells derived from pregnant and pseudopregnant mice. The implications of these changes still remain unclear.

  20. Erodabilidad y erosión hídrica potencial en un sector de la cuenca del rio Otún - Colombia

    Madero Morales Edgar Enrique

    1996-12-01

    Full Text Available

    The present research seeks to determine the applicability of simple, rapid and economic methods tor comparing the soil erodability under twelve cultivation systems, and besides to record the features of rill erosion under ale crops in the watershed area of the Otún river. Here the denudation processes are common and affect a large portion of the area. The erodability tests considered (crumb, pinhole, manipulation, rain acceptance, soil loss, shear strenght are related to soil toss with reference to erodable material and the volume of surface flow. These do not seek to quantify the actual or potential soil loss of a place, but can help in the estimation of the variability of soil erodability with the content of surface gravel, the state soil moisture content and time. To predict the advance of rill and interril erosion in bare soil, Bergsma (1989 developed a semicuantitative system with this purpose, and what is related to the presence and frequency of six microtopography soil surface features after each rain and at the end of tillage: original clods, eroding clods, depressional areas, linear flow pattern of shallow channels and deeper rills, and coverage (vegetation, gravel, etc.; each feature has a length less than 25 cm. The erodability tests demonstrate their practical value with no more than three repetitions per unit of management. There was more soils (8/12 with low erodability. The evolution of microtopograhy soil surface features showed that corn, bean and grass increased depressional areas and shallow channels; the tendency in onion was similar but with a relatibility increase in deeper rills. Bean and grass crops were the less erosion hazard uses because they let a few loss of soil at the more inestable terrains. Contrary, corn and onion are not the most recomendable uses because they allowed the biggest advance of erosion in the most stable soils.

    Las pruebas de erodabilidad consideradas (terrón, agujero, manipulación o

  1. Investigación y práctica urbanística desde la Escuela de Arquitectura de Madrid : 20 años de actividad del Instituto Juan de Herrera (SPyOT, 1977-1997

    Ramón López de Lucio

    1997-11-01

    For two decades now, research and urban practice at Escuela Técnica Superior de Arquitectura de Madrid has notably come apart from dominant planning ideology, in which "urban project" has been considered from a quite reductionist approach, so embedded in the paradigmatic tautology of "urban urbanism", as the only way of working and teaching. In 1977 a group of professors of what latter became the Departamento de Urbanística y Ordenación del Territorio de la E.T.S. de Arquitectura de Madrid decided to organize themselves as a working group with the objective of developing research projects and eventually professional work of particular interest in the fields of city and regional planning. Under the name of Seminario de Planeamiento y Ordenación del Territorio (SPyOT this group started a series of research projects focusing initially in Madrid -as central object of study and laboratory of new planning initiatives- and in the comprehensive plans of the main Spanish cities. After 20 years of uninterrupted activity the initial group has grown and consolidated, and its fields of activity have expanded. More than one hundred projects coordinated by two dozens of professors have been completed in which about 200 hundred students have cooperated. A permanent platform for research within the university has developed and an alternative for professional work for full-time professors has been created, following the guidelines of the University Reform Law (LRU. A considerable number of outstanding students have started careers in the planning field, both in the public and private sectors. After 20 years it can be said that the always difficult relationship between academia and the professional world, both for students and professors, has been facilitated by the existence of the SPyOT. Today the SPyOT has become the Sección de Urbanismo del Instituto Juan de Herrera. This publication includes, after some introductory remarks by the Directors of the Planning Department of the

  2. Modifications to the restriction method of Gentry and Casanas for otariid pups Modificaciones al método de restricción de Gentry y Casanas para crías de otáridos

    Janitzio Égido-Villarreal

    2007-06-01

    Full Text Available To avoid risky and expensive chemical immobilization of otariid pups, physical restriction is a better option. For this reason we constructed a stretcher that permits wide liberty to interact with the pup and take a variety of samples in a safe, comfortable and easy way, for both the pup and the researcher.Para evitar el uso de la riesgosa y cara restricción química en crías de otáridos la mejor opción es la restricción física. Por lo anterior construimos una camilla que permite amplia libertad para la toma de diferentes tipos de muestras de manera segura, cómoda y fácil tanto para la cría como para el investigador.

  3. Patrones de relación entre información biológica e información física y socioeconómica : cuenca alta del Río Otún, Risaralda Colombia

    Coronel Picón, Yulieth Rossio

    2009-01-01

    En este trabajo se realizó un análisis de información física, socioeconómica y biológica de la cuenca del río Otún. Se presenta la metodología utilizada para la identificación de patrones de relación entre la información física y socioeconómica de la cuenca y la presencia de algunos mamíferos identificados en esta zona, y los resultados obtenidos. La identificación de patrones se llevó a cabo mediante la aplicación de árboles de decisión, utilizando el algoritmo j-48 desarrollado en el entorn...

  4. Investigations of the 0.020-scale 88-OTS Integrated Space Shuttle Vehicle Jet-Plume Model in the NASA/Ames Research Center 11 by11-Foot Unitary Plan Wind Tunnel (IA80). Volume 1

    Nichols, M. E.

    1976-01-01

    The results are documented of jet plume effects wind tunnel test of the 0.020-scale 88-OTS launch configuration space shuttle vehicle model in the 11 x 11 foot leg of the NASA/Ames Research Center Unitary Plan Wind Tunnel. This test involved cold gas main propulsion system (MPS) and solid rocket motor (SRB) plume simulations at Mach numbers from 0.6 to 1.4. Integrated vehicle surface pressure distributions, elevon and rudder hinge moments, and wing and vertical tail root bending and torsional moments due to MPS and SRB plume interactions were determined. Nozzle power conditions were controlled per pretest nozzle calibrations. Model angle of attack was varied from -4 deg to +4 deg; model angle of sideslip was varied from -4 deg to +4 deg. Reynolds number was varied for certain test conditions and configurations, with the nominal freestream total pressure being 14.69 psia. Plotted force and pressure data are presented.

  5. Results of investigations conducted in the LaRC 4-foot unitary plan wind tunnel leg no. 1 using the 0.010-scale 72-OTS model of the space shuttle integrated vehicle (IA94A)

    Nichols, M. E.

    1976-01-01

    Aero-loads investigations were conducted on the updated configuration-5 space shuttle launch vehicle at Mach numbers 2.50, 3.50, and 4.50. Six-component vehicle forces and moments, base and sting-cavity pressures, elevon hinge moments, wing-root bending and torsion moments, and normal shear force data were obtained. Full simulation of updated vehicle protuberances and attach hardware was employed. Various elevon deflection angles were tested, with two different forward orbiter-to-external-tank attach-strut configurations. The entire vehicle model 72-OTS was supported by means of a balance mounted in the orbiter through its base and suspended from an appropriate sting for the specific tunnel.

  6. Testimonios arqueológicos del Oriente Próximo reflejados en el Séfer–Masa`ot de Benjamín de Tudela (Siria-Palestina, Mesopotamia y Egipto

    Magdalena Nom de Déu, José Ramón

    2005-04-01

    Full Text Available Benjamín de Tudela (en hebreo Biniamín ben rabbí Yonah mi- Tudela es, sin duda, un navarro universal. Judío de la aljama tudelana, se ignora la fecha de su nacimiento (acaso hacia 1130. Hijo de rabino y viajero infatigable, sólo sabemos de este personaje lo poco que de él se menciona en su famoso Libro de Viajes o Séfer-masa`ot, fruto de sus vivas experiencias —las más de las veces directas— exquisitamente plasmadas en su relación de viaje, redactadas en hebreo. Conocedor del romance navarro vernáculo de la época, sabía hebreo - su lengua de instrucción y cultivo literario- y árabe, entendiendo acaso el griego y el latín.…

  7. Vy jste mi z té otázky utekl (analýza jednoho způsobu vymáhání odpovědi s využitím korpusových dokladů)

    Jílková, Lucie

    2015-01-01

    Roč. 97, č. 1 (2015), s. 31-11 ISSN 0008-7386 R&D Projects: GA ČR GAP406/12/1829 Institutional support: RVO:68378092 Keywords : the expression vy mi utíkáte z otázky * the SYN2013PUB corpus * the DIALOG corpus, metaphor Subject RIV: AI - Linguistics

  8. "Courageous, Zealous, Learned, Wise, and Chaste" - Queen Elizabeth I's Biblical Analogies After Her Death

    Aidan Norrie

    2015-11-01

    Full Text Available During her reign, Queen Elizabeth I of England was the subject of various biblical analogies. Much of the current historiography, however, does not continue analysis of these literary devices after the Queen's death in 1603. Primary source documents show that their use did not cease with the Queen's death. These analogies appear to have continued for two primary purposes. Analogies legitimised a questionable event that had occurred during Elizabeth's reign, and portrayed these decisions as an example for the current Protestant monarch to imitate. Also, in the years after the Queen's death, analogies reinforced England's Protestantism (and its divine sanction, and gave the Stuart monarchs an example to emulate in religio-political matters.

  9. Vitex agnus-castus (Chaste-Tree/Berry) in the treatment of menopause-related complaints.

    van Die, Margaret Diana; Burger, Henry G; Teede, Helena J; Bone, Kerry M

    2009-08-01

    The origin of the current practice of administering Vitex agnus-castus in menopause-related complaints is uncertain, but appears to be relatively recent. Here we review the evidence for this application of Vitex based on evidence from pharmacological studies and clinical research. The mechanisms of potential relevance in the context of menopause are explored with reference to the current understanding of the endocrinology and neuroendocrinology of menopause and associated symptoms. We conclude that, while evidence from rigorous randomized controlled trials is lacking for the individual herb in this context, emerging pharmacological evidence supports a role for V. agnus-castus in the alleviation of menopausal symptoms and suggests that further investigation may be appropriate.

  10. Bērnu mārketinga attīstība Latvijas lielāko pārtikas produktu ražotāju tirgus darbībās

    Lūse, Ieva

    2010-01-01

    Uzņēmumi visā pasaulē arvien vairāk sāka apzināties bērnu potenciālu tirgū un aktivizē savu komunikāciju ar bērnu auditoriju. Bērni vienlaicīgi tirgū pilda vairākas lomas kā patērētāji, iniciatori, ietekmētāji un lēmēji par pirkumu un pircēji šodien un nākotnē, kļūstot par daudzu uzņēmumu produkcijas pamata patērētājiem. Ņemot vērā tēmas aktualitāti autore par maģistra darba mērķi izvirza apzināt un analizēt lielāko Latvijas pārtikas produktu ražotāju aktivitāti bērnu mārketing...

  11. Opryszczkowe zapalenie mózgu przebiegające w postaci szybko narastającego zespołu otępiennego u chorej na reumatoidalne zapalenie stawów, leczonej infliksymabem

    Justyna Swarowska-Knap

    2011-06-01

    Full Text Available Przedstawiono przypadek 53-letniej chorej na reumatoidalnezapalenie stawów (RZS o ciężkim, opornym na standardoweleczenie przebiegu, leczonej wieloma lekami modyfikującymi przebiegchoroby (LMPCh oraz glikokortykosteroidami, u którejw trakcie leczenia antycytokinowego (infliksymabem wystąpiłyobjawy szybko narastającego zespołu otępiennego. Ze względu nacoraz powszechniejsze zastosowanie leków antycytokinowych nietylko w dziedzinie reumatologii, coraz częściej w literaturze światowejpojawiają się doniesienia o związanych z ich stosowaniemdziałaniach niepożądanych, w tym powikłaniach infekcyjnychi zaburzeniach ze strony ośrodkowego układu nerwowego. Zaburzenianeurologiczne obserwowano w trakcie leczenia wszystkimiinhibitorami czynnika martwicy nowotworów α (tumour necrosisfactor α – TNF-α. Wśród nich występowały: parestezje (65% chorych,zaburzenia widzenia związane z zapaleniem nerwu wzrokowego(40% chorych i splątanie (25% chorych. Ponadto, wgdanych literaturowych, u chorych na RZS leczonych immunosupresyjnieistnieje większe niż w populacji ogólnej ryzyko poważnychinfekcji oraz reaktywacji latentnych infekcji wirusowych,w tym infekcji wirusami z rodziny Herpesviridae i wirusem JC. Ze względu na możliwy związek szybko ujawniających się zaburzeńneurologicznych z leczeniem infliksymabem wysunięto u pacjentkipodejrzenie postępującej wieloogniskowej leukoencefalopatii(progressive multifocal leukoencephalopathy – PML, będącej wynikiemaktywacji utajonej infekcji wirusem JC. W wykonanym badaniuMRI mózgowia stwierdzono obecność hiperintensywnychzmian zlokalizowanych w istocie białej oraz szarej płatów czołowychi skroniowych, które nie dawały efektu masy (ryc. 1. Lokalizacjazmian w płatach skroniowych była typowa dla opryszczkowegozapalenia mózgu (herpes simplex encephalitis – HSE, aleobecnie wiadomo, że podobne zmiany mogą także występowaćw PML. Obie neuroinfekcje mogą przebiega

  12. Crystal structure of the regulatory subunit of archaeal initiation factor 2B (aIF2B) from hyperthermophilic archaeon Pyrococcus horikoshii OT3: a proposed structure of the regulatory subcomplex of eukaryotic IF2B

    Kakuta, Yoshimitsu; Tahara, Maino; Maetani, Shigehiro; Yao, Min; Tanaka, Isao; Kimura, Makoto

    2004-01-01

    Eukaryotic translation initiation factor 2B (eIF2B) is the guanine-nucleotide exchange factor for eukaryotic initiation factor 2 (eIF2). eIF2B is a heteropentameric protein composed of α-ε subunits. The α, β, and δ subunits form a regulatory subcomplex, while the γ and ε form a catalytic subcomplex. Archaea possess homologues of α, β, and δ subunits of eIF2B. Here, we report the three-dimensional structure of an archaeal regulatory subunit (aIF2Bα) from the hyperthermophilic archaeon Pyrococcus horikoshii OT3 determined by X-ray crystallography at 2.2 A resolution. aIF2Bα consists of two subdomains, an N-domain (residues 1-95) and a C-domain (residues 96-276), connected by a long α-helix (α5: 78-106). The N-domain contains a five helix bundle structure, while the C-domain folds into the α/β structure, thus showing similarity to D-ribose-5-phosphate isomerase structure. The presence of two molecules in the crystallographic asymmetric unit and the gel filtration analysis suggest a dimeric structure of aIF2Bα in solution, interacting with each other by C-domains. Furthermore, the crystallographic 3-fold symmetry generates a homohexameric structure of aIF2Bα; the interaction is primarily mediated by the long α-helix at the N-domains. This structure suggests an architecture of the three subunits, α, β, and δ, in the regulatory subcomplex within eIF2B

  13. Ot porolona k iskusstvu / Kristiina Verbitskaja

    Verbitskaja, Kristiina

    2004-01-01

    Tallinna endise tehase "Polümeer" ruumides tegutsevad juba kaks aastat muusikud, kunstnikud ja teised kultuuriinimesed. 10. -20. augustini toimuvad kultuuritehase Polymer avamisüritused: teatrietendused, kunstinäitused, kontserdid, filmiseansid. Korraldab Madis Mikkor

  14. Poslanije ot propavshih ekspeditsi / Aleksandra Manukjan

    Manukjan, Aleksandra

    2001-01-01

    Kadunud ekspeditsioonidele pühendatud näitusest (mereteemalised pildid ja paberist jäämäed peidetud proviandiga) Tallinna Meremuuseumis, autoriteks Roman Matkiewicz ja Aleksandr Belanov (Moskva, rühmitus MEKVA). Lühidalt rühmitusest Mekva.

  15. Loomakujukesed Valma keskneoliitilises kaksikmatuses / Mirja Ots

    Ots, Mirja

    2010-01-01

    Artiklis käsitletakse Valma keskneoliitilisest asulakohast avastatud mehe ja naise ühishauast leitud sarvest ja merevaigust loomakujukesi. Ülevaade haua avastamisest, hauapanuste leiust, kujukeste võimalikust päritolust, funktsioonist ja tähendusest

  16. God ot goda populjarneje / Aadu Kana

    Kana, Aadu

    2005-01-01

    Parima betoonehitise konkursist. Aasta betoonehitis 2004 - Ülemiste hotell, arhitekt Martin Aunin, projekteerija AS EA Reng, konstruktsioonid: IB Pike, ehitaja AS FKSM, betoon: AS HC Betoon. Eeriauhinnad: Rakvere spordihalli ja Veskimöldre lasteaia betoonelementide tootja E-Betoonelement, IB Pike ja Tiit Masso City Plaza konstruktsioonide eest, Kakumäel asuva eramu tellija ja sisekujundaja Raina Lillepõld

  17. Sedamoodi 2005 : moda ot shkolnikov / Marina Poltavtseva

    Poltavtseva, Marina

    2005-01-01

    Tallinna koolide õpilaste moekonkursist "Sedamoodi" räägib konkursi organisaator Tallinna Kanutiaia Noortemaja direktor Mari Velleste. Sedamoodi 2005 eri vanusegruppide võitjad. Rändauhinnaks on Tauno Kangro skulptuur

  18. Ot rokoko do romantizma / Jevgeni Ashihmin

    Ashihmin, Jevgeni

    2006-01-01

    Suveekskursioonide tsüklist "Eesti kunsti ajaloost" Kumus. Ekskursioonid teemadel "Rokokoost romantismini","Modernism. II Maailmasõja eelne eesti kunst" ja "Eesti kunst nõukogude perioodil". Ekskursioone juhivad kunstiteadlased Helena Risthein ja Karin Taidre

  19. Ot Kannskogo festivalja kruzhitsja golova / Jaak Lõhmus

    Lõhmus, Jaak

    2008-01-01

    Cannes'i 61. filmifestivalist, lähemalt Woody Alleni filmist "Vicky, Cristina, barcelona ja võistlusprogrammi avafilmist "Pimedus" (režissöör Fernando Meirelles). Ka Veiko Õunpuust, kes on saabunud Euroopa talendi auhinda vastu võtma

  20. Ofitserski mundir ot Hugo Boss / Mark Ostanin

    Ostanin, Mark

    2003-01-01

    Antikvaarsete esemete laat Kurtnas. Müügil olevatest ajaloolistest rekonstruktsioonidest. Saksa armee ohvitserimundri taastamise keerulisusest rohkete vigur-detailide tõttu. Mundri disainerina mainitakse Hugo Bossi

  1. Exploring Cultural Competence amongst OT Students.

    Govender, Pragashnie; Mpanza, December M; Carey, Tarryn; Jiyane, Kwenzile; Andrews, Bicolé; Mashele, Sam

    2017-01-01

    Occupational therapy relies primarily on communication between the therapist and client for effective intervention. Adequate communication may be influenced by language and cultural differences between the therapist and client. Cultural competence in relation to language and culture is thus a vital part in practice. Limited research exists on cultural competence in occupational therapy students. This study thus aimed to explore the cultural competence of final year students and their perceptions of their own cultural competence, with respect to language and culture in their practice as students. An explorative qualitative study design was utilised with a nonprobability purposeful sample of 21 final year undergraduate students at a tertiary institute in South Africa. Three focus groups were conducted, comprising between 6 and 8 students in each group. Thematic analysis using inductive reasoning was undertaken in order to analyse the students' experiences and understanding of cultural competence. Findings of the study suggest that cultural competence, in relation to language and culture, influences the occupational therapy intervention process. It was shown to both positively and negatively influence intervention through supporting or hindering rapport building, client centeredness, and effective intervention.

  2. Tõsielust midagi jaburamat ei ole / Kristjan Ots

    Ots, Kristjan

    2004-01-01

    PÖFFi filme - mängufilmid "Kadudega tuleb arvestada" ("Mit Verlust ist zu Rechnen") : režissöör Ulrich Seidl : Austria 1992 ja "Tş̌ehhi unelm" ("Česky sen") : režissöörid Vit Klusak ja Filip Remunda : Tšehhi 2004

  3. Exploring Cultural Competence amongst OT Students

    Pragashnie Govender

    2017-01-01

    Full Text Available Occupational therapy relies primarily on communication between the therapist and client for effective intervention. Adequate communication may be influenced by language and cultural differences between the therapist and client. Cultural competence in relation to language and culture is thus a vital part in practice. Limited research exists on cultural competence in occupational therapy students. This study thus aimed to explore the cultural competence of final year students and their perceptions of their own cultural competence, with respect to language and culture in their practice as students. An explorative qualitative study design was utilised with a nonprobability purposeful sample of 21 final year undergraduate students at a tertiary institute in South Africa. Three focus groups were conducted, comprising between 6 and 8 students in each group. Thematic analysis using inductive reasoning was undertaken in order to analyse the students’ experiences and understanding of cultural competence. Findings of the study suggest that cultural competence, in relation to language and culture, influences the occupational therapy intervention process. It was shown to both positively and negatively influence intervention through supporting or hindering rapport building, client centeredness, and effective intervention.

  4. Results of a M = 5.3 heat transfer test of the integrated vehicle using phase-change paint techniques on the 0.0175-scale model 56-OTS in the NASA/Ames Research Center 3.5-foot hypersonic wind tunnel

    Marroquin, J.

    1985-01-01

    An experimental investigation was performed in the NASA/Ames Research Center 3.5-foot Hypersonic Wind Tunnel to obtain supersonic heat-distribution data in areas between the orbiter and external tank using phase-change paint techniques. The tests used Novamide SSV Model 56-OTS in the first and second-stage ascent configurations. Data were obtained at a nominal Mach number of 5.3 and a Reynolds number per foot of 5 x 10 to the 6th power with angles of attack of 0 deg, +/- 5 deg, and sideslip angles of 0 deg and +/- 5 deg.

  5. diag ostic efficacy of i direct hemaggluti atio test i relatio to kato ...

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    ... of Veterinary Medicine,. Addis Ababa University, P. O. Box 34, Debre Zeit, Ethiopia ... certified technicians using disposable syringes. The blood was allowed to ... school teachers and the study participants/school children. Then, about 2 ml ...

  6. Comparing concentration methods: parasitrap® versus Kato-Katz for ...

    haran Africa, afflicting both children and adults with their level of prevalence depending ... host and infected whether by oral or by dermal channels. (in the case of .... Discussion. The pathologies caused by parasites are, in the majority of cases ...

  7. Identity of Innovative Multifunctional Material Manufacturing Business in Latvia / Inovatīvu Daudzfunkcionālo Materiālu Ražotāju Identitāte Latvijā

    Geipele, I.; Staube, T.; Ciemleja, G.; Zeltins, N.; Ekmanis, Yu.

    2015-08-01

    The publication comprises the results from the practical scientific investigation to define the profile and distinctions of the Latvian innovative multifunctional material manufacturing industry. The research is carried out by a holistic approach, including expert interviews, qualitative analysis of the official register data, practical survey, and financial data analysis. The paper seeks to give the detailed data on a technological profile of the mentioned representative companies, if there is a synergy or tough competition in the Latvian market. The current research is topical, because it is unique and does not have analogues in Latvia, and the research is timely due to correspondence with recently stated Research and Innovation Strategies for Smart Specialisation in Latvia. The main findings are associated with recognition of the factors that make impact on commercialisation of the finished goods, obtained financial results and planned directions of development of the respondent companies. Publikācija sniedz veiktā zinātniski praktiskā pētījuma rezultātus, kura ietvaros tika noteikts Latvijas inovatīvu daudzfunkcionālo materiālu ražotāju darbības profils un identitāte. Pētījumā tika izmantota kompleksās analīzes metode, kas ietvēra ekspertu intervijas, uzņēmumu oficiāli reģistrēto datu kvalitatīvo analīzi, zinātniski praktisko aptauju, kā arī pētāmo uzņēmumu finanšu darbības rezultātu analīzi. Zinātniskais darbs sniedz izsmeļošu informāciju par mērķa uzņēmumu tehnoloģisko profilu un pēta, vai Latvijas mērķa ražošanas nozarē ir sinerģijas vai sīvās konkurences pazīmes. Šim zinātniskajam pētījumam ir noteikta aktualitāte saskaņā ar tā unikalitāti Latvijas valsts mērogā un atbilstība Viedās specializācijas stratēģijai. Pētījuma galvenie secinājumi ir saistīti ar uzņēmumu produkcijas komercializācijas ietekmējošo faktoru apzināšanu, sasniegtajiem finansiālajiem rezultātiem un pl

  8. Radiation physics of non-metallic crystals. Volume III, No. 3. Radiatsionnaya fizika nemetallicheskikh kristallov. Tom III, Chast 3

    Konozenko, I D [ed.

    1971-01-01

    Separate articles are presented on studies concerned with radiation phenomena in ionic crystals and dielectrics. Topics include energy losses and electron escape in monocrystals, non-stationary acoustic absorption in monocrystals, charge behavior in radioactive dielectrics, the effects of electron radiation on the electroconductivity of organic dielectrics, adsorption of polyatomic gases in adsorbents, catalysis and inhibition of solid inorganic salt radiolysis, and the formation of additive paramagnetic centers in gamma radiated salts of alkaline earth metals. 253 references.

  9. Fluktuacja dynamiki i dymorfizm płciowy cech somatycznych, typu budowy i otłuszczenia ciała dzieci i młodzieży w wieku od 4 do 18 lat środowiska wiejskiego regionu warmińsko-mazurskiego

    Mirosław Mrozkowiak

    2015-07-01

    Mirosław Mrozkowiak   Mirosław Mrozkowiak Bioergonsport, Nowa Biała. Polska e-mail: magmar54@interia.pl strona: http://wadypostawy.republika.pl   Słowa kluczowe: wysokość i masa ciała, wskaźnik BMI, IR.   Streszczenie Wstęp. Mimo sekularnego zwiększenia wysokości ciała we wszystkich grupach i płciach, dystanse międzyśrodowiskowe nie wykazywały tendencji malejących, jednak wszystkie populacje dążą do pewnej stabilizacji. Powszechnie stosowany wskaźnik wagowo-wzrostowym BMI umożliwił diagnostykę otyłości i nadwagi, a wskaźnik IR określenie typu budowy ciała. Celem badań jest określenie dynamiki zmian i dymorfizmu płciowego cech somatycznych, typu budowy i otłuszczenia ciała dzieci i młodzieży w wieku od 4 do 18 lat środowiska wiejskiego, regionu warmińsko-mazurskiego Polski. Metoda i materiał. Z badań uzyskano 8270 obserwacji w tym 3384 wśród dziewcząt i 3786 chłopców. Pomiarów dokonano na wadze lekarskiej z dokładnością do 0,5 cm i 100 g. Wyniki. Statystykę opisową wskaźnika BMI przedstawiono w tab. 2 oraz ryc. 1. Dynamikę zmian i istotność różnic między płciami w kategoriach wiekowych w tab. 3 i 4 oraz ryc. 2. Statystykę opisową wskaźnika IR przedstawiono w tab. 5 i ryc. 3. Dynamikę zmian i istotność różnic między płciami w kategoriach wiekowych w tab. 6 i 7 oraz ryc. 4. W tab. 8 przedstawiono przyjętą interpretację wskaźnika IR, w 9 wskaźnika BMI, w tab. 10, 11 i 12 oraz ryc. od 5 do 9 przedstawiony jest odsetek typów budowy i otłuszczenia występujący w badanej kohorcie. Wnioski. 1. Średnia wysokość i masa ciała chłopców w wieku od 4 do 18 r.ż. jest większa niż dziewcząt w tym samym wieku. 2. Wśród dziewcząt i chłopców dominuje smukły typ budowy ciała. Wśród chłopców w wieku 17 lat występuje tylko typ smukły, a w 18 r.ż. średni. 3. Odsetek z niedowagą utrzymuje się na wysokim poziomie wśród dziewcząt i chłopców do 8 r.ż., później sukcesywnie obni

  10. Parity-Time Symmetry and the Toy Models of Gain-Loss Dynamics near the Real Kato's Exceptional Points

    Znojil, Miloslav

    2016-01-01

    Roč. 8, č. 6 (2016), s. 52 ISSN 2073-8994 R&D Projects: GA ČR GA16-22945S Institutional support: RVO:61389005 Keywords : parity-time symmetry * Schrodinger equation * physical Hilbert space * inner-product metric operator * real exceptional points * solvable models * quantum Big Bang * quantum Inflation period Subject RIV: BE - Theoretical Physics Impact factor: 1.457, year: 2016

  11. Surface potential domains on lamellar P3OT structures

    Perez-GarcIa, B [Departamento Fisica, Facultad de Quimica (Campus Espinardo), Universidad de Murcia, E-30100 Murcia (Spain); Abad, J [Departamento Fisica, Facultad de Quimica (Campus Espinardo), Universidad de Murcia, E-30100 Murcia (Spain); Urbina, A [Departamento Electronica, TecnologIa de Computadoras y Proyectos, Universidad Politecnica de Cartagena, E-30202 Cartagena (Spain); Colchero, J [Departamento Fisica, Facultad de Quimica (Campus Espinardo), Universidad de Murcia, E-30100 Murcia (Spain); Palacios-Lidon, E [Departamento Fisica, Facultad de Quimica (Campus Espinardo), Universidad de Murcia, E-30100 Murcia (Spain)

    2008-02-13

    In this work the electrostatic properties of poly(3-octylthiophene) thin films have been studied on a nanometer scale by means of electrostatic force microscopy and Kelvin probe microscopy (KPM). The KPM images reveal that different surface contact potential domains coexist on the polymer surface. This result, together with additional capacitance measurements, indicates that the potential domains are related to the existence of dipoles due to different molecular arrangements. Finally, capacitance measurements as a function of the tip-sample bias voltage show that in all regions large band bending effects take place.

  12. ater hy ater uota Systems In hina are ot orkin

    commerce and urban communities compete for ... China's Heihe River Basin by Junlian Zhang, College of Resource and Environment,. China Agricultural ... Adherence to water quotas in five irrigation areas in Zhangye City. Hongshuihe. 4.1.

  13. Treatability study Number PDC-1-O-T. Final report

    1998-01-01

    Los Alamos National Laboratory provided treatability study samples from four waste streams, designated Stream number-sign 1, Stream number-sign 3, Stream number-sign 6, and Stream number-sign 7. Stream number-sign 1 consisted of one 55-gallon drum of personal protective equipment (PPE), rags, and neutralizing agent (bicarbonate) generated during the cleanup of a sodium dichromate solution spill. Stream number-sign 3 was one 55-gallon drum of paper, rags, lab utensils, tools, and tape from the decontamination of a glovebox. The sample of Stream number-sign 6 was packaged in three 30-gallon drums and a 100 ft 3 wooden box. It consisted of plastic sheeting, PPE, and paper generated from the cleanup of mock explosive (barium nitrate) from depleted uranium parts. Stream number-sign 7 was scrap metal (copper, stainless and carbon steel joined with silver solder) from the disassembly of gas manifolds. The objective of the treatability study is to determine: (1) whether the Perma-Fix stabilization/solidification process can treat the waste sample to meet Land Disposal Restrictions and the Waste Acceptance Criteria for LANL Technical Area 54, Area G, and (2) optimum loading and resulting weight and volume of finished waste form. The stabilized waste was mixed into grout that had been poured into a lined drum. After each original container of waste was processed, the liner was closed and a new liner was placed in the same drum on top of the previous closed liner. This allowed an overall reduction in waste volume but kept waste segregated to minimize the amount of rework in case analytical results indicated any batch did not meet treatment standards. Samples of treated waste from each waste stream were analyzed by Perma-Fix Analytical Services to get a preliminary approximation of TCLP metals. Splits of these samples were sent to American Environmental Network's mixed waste analytical lab in Cary, NC for confirmation analysis. Results were all below applicable limits

  14. Kontrastõ ot Baltika Grupp / Jana Kuvaitseva

    Kuvaitseva, Jana

    2007-01-01

    Eesti rõivatootja Baltika Grupp uutest sügis-talvistest kollektsioonidest räägivad Montoni kaubamärgi disainerid Jaanika Sootna ja Evelin Lill ning Ivo Nikkolo kaubamärgi disainer Eve Hanson. Baltika kaubamärgid on Monton, Mosaic, Baltman ja Ivo Nikkolo

  15. Surface potential domains on lamellar P3OT structures

    Perez-GarcIa, B; Abad, J; Urbina, A; Colchero, J; Palacios-Lidon, E

    2008-01-01

    In this work the electrostatic properties of poly(3-octylthiophene) thin films have been studied on a nanometer scale by means of electrostatic force microscopy and Kelvin probe microscopy (KPM). The KPM images reveal that different surface contact potential domains coexist on the polymer surface. This result, together with additional capacitance measurements, indicates that the potential domains are related to the existence of dipoles due to different molecular arrangements. Finally, capacitance measurements as a function of the tip-sample bias voltage show that in all regions large band bending effects take place

  16. Polnõi shabash ot Emira Kusturitsõ

    2001-01-01

    Emir Kusturica esines orkestri No Smoking Orchestra koosseisus Moskvas ja Peterburis. Sellest juba 1980. aastal Sarajevos loodud orkestrist on ta teinud dokumentaalfilmi "Super 8 Stories by Emir Kusturica"

  17. Elaboration d'entrep\\^ots de donn\\'ees complexes

    Teste, Olivier

    2010-01-01

    In this paper, we study the data warehouse modelling used in decision support systems. We provide an object-oriented data warehouse model allowing data warehouse description as a central repository of relevant, complex and temporal data. Our model integrates three concepts such as warehouse object, environment and warehouse class. Each warehouse object is composed of one current state, several past states (modelling its detailed evolutions) and several archive states (modelling its evolutions...

  18. Film o katastrofje "Estonii" budjet javno daljok ot deistvitelnosti

    2001-01-01

    Kavandatavast katastrooffilmist "Baltic Storm", mis on ajendatud väidetest, et parvlaev "Estonia" uputati. Stsenaristiks on saksa teleajakirjanik Jutta Rabe, kes koos advokaat Kaj Holmbergiga lõi selleks puhuks stuudio Top Story. Peaosalisi mängivad Greta Scacchi (41) ja Jürgen Prochnow (60)

  19. Intercomparison ot the PTB and LMRI standards in beta dosimetry

    Hillion, P.; Simoen, J.P.; Boehm, J.

    1976-12-01

    To set up national standard measuring devices for verifying the unit of the quantity 'absorbed dose rate in soft tissue' at different depths for β-radiation, extrapolation chambers have been developed at the PTB and LMRI. They are constructed of nearly tissue equivalent materials and connected to measuring devices of highest metrological quality. A comparison of these standards has been carried out using two β-ray sources of 90 Sr + 90 Y, one from each laboratory. Absorbed dose rates between 0,5 Gy h -1 and 1.3 Gy -1 have been determined. The overall uncertainties of the absorbed dose rates in tissue are 1.8%. The part of the uncertainty due to systematic uncertainties of corrections unique for each laboratory amounts to 0.8% for the LMRI and 0.7% for the PTB. The ratios of the corresponding absorbed dose rates measured at the PTB and at the LMRI differ by 0.2% to 0.7%. On the average, the LMRI values are 0.4% samller than the PTB values. The agreement is felt to be very satisfactory. (orig.) [de

  20. Pirozhki s izjuminkoi ot Suini i Ko / Boris Tuch

    Tuch, Boris, 1946-

    2008-01-01

    Õudusmuusikal "Sweeney Todd : Fleet Streeti deemonlik habemeajaja" Stephen Sondheimi muusikali alusel : režissöör Tim Burton : peaosades Johnny Depp, Helena Bonham Carter : Ameerika Ühendriigid - Suurbritannia 2007

  1. JeS zhdjot ot Rossii podtverzhdenija / Marko Saaret

    Saaret, Marko

    2004-01-01

    Euroopa Komisjoni president Romano Prodi, välisasjade komissar Chris Patten ja kaubandusvolinik Pascal Lamy alustavad visiiti Moskvasse. Venemaalt oodatakse lõplikku kinnitust kirjutamaks alla partnerluse ja koostöö lepingu laienemisele uute EL-i riikidega enne 1. maid

  2. "Kalev" izbavilsja ot pishtshevõhh "dobavok" / Hilda Vall

    Vall, Hilda

    2007-01-01

    Ärimees Oliver Kruuda teatas oma piimatööstuse Tere ja kondiitritööstuse Kalev müügist Eesti investeerimisfirmale Alta Capital Partners, põhjendades oma otsust sooviga edaspidi tegutseda kinnisvara ja meedia vallas

  3. 12 CFR 574.7 - Determination by the OTS.

    2010-01-01

    ... days of such request on the competitive factors involved. Acquisitions involving mergers (including...) [Reserved] (g) Presumptive disqualifiers—(1) Integrity factors. The following factors shall give rise to a...) Violation of the rules, regulations, codes of conduct or ethics of a self-regulatory trade or professional...

  4. Tshto nuzhno amerikantsam ot rossiskoi zhivopisi / Natalia Kolodzei

    Kolodzei, Natalia

    2004-01-01

    Intervjuu Washington ProFile'ilt vene- ja nõukogude kunsti erakogu baasil loodud fondi "Kolodzei Art Foundation" (1991) ühe rajaja, tegevdirektori ja kuraatoriga nõukogude ja vene kunsti propageerimisest ja näituste korraldamisest USA-s

  5. Kunstniku nimi paanidena seinal / Ille Grün-Ots

    Grün-Ots, Ille, 1960-2016

    2006-01-01

    Luksuslikest disaintapeetidest, mis kannavad kunstniku nime. Inglise kunstniku William Morrise (1834-1896) kujundatud tapeete müüakse Morris&Co nime all. Huvitavaid disaintapeete pakub firma Disain Digest, kust leiab Sahco Hessleini, Ulf Moritza jt. kujundatud tapeete

  6. Mozhet li natsija zashtshitit ot natsionaliszma? / Sergei Ivanov

    Ivanov, Sergei, 1958-

    2006-01-01

    Euroopa Nõukogu Parlamentaarne Assamblee (ENPA) käsitleb küsimust, kas rahvuse mõiste täpsustamine võib aidata tagada rahvusvähemuste õigusi 21. sajandi Euroopas. Rahvuse mõiste muutumisest läbi ajaloo, ENPA seisukohtadest, mis puudutavad rahvusvähemusi

  7. Letni sezon : ot avangardista do "Sjurrealistov" / Boris Tuch

    Tuch, Boris, 1946-

    2006-01-01

    Suvelavastustest: Andrus Kivirähk "Sürrealistid" Viinistus (lavastaja Hendrik Toompere jun), Mart Kivastik "Kits viiuli ja õngega" Viinistus (lavastaja Raimo Pass), Alfred Jarry "Kuningas Ubu" Teater NO99 Haapsalu Kiltsi lennuvälja angaarides (lavastajad Ene-Liis Semper ja Tiit Ojasoo), Jaan Tätte "Kaev" Tallinna Linnateatri siseõues (lavastaja Indrek Sammul)

  8. JUNESKO v uzhase ot tsentra "Viru" / Jekaterina Rodina

    Rodina, Jekaterina

    2005-01-01

    UNESCO maailmapärandi komitee ekspert arutas Tallinna linnavõimudega bastionide ja linnamüüri kasutamise ning linna merele avamise küsimusi. Ekspert kritiseeris Tallinna linnaplaneerimist, näitena tõi Viru Keskuse vanalinna läheduses

  9. An OT Account of Laryngealization in Cuzco Quechua.

    Parker, Steve

    Classical phonemic accounts of Cuzco (Peru) Quechua posit three distinct types of stops: plain, aspirated, and glottalized. A later analysis argued instead for a root-level feature of laryngealization governed by a small number of formal mechanisms. This latter analysis is taken one step further, showing that even greater explanatory power may be…

  10. Speed ot travelling waves in reaction-diffusion equations

    Benguria, R.D.; Depassier, M.C.; Mendez, V.

    2002-01-01

    Reaction diffusion equations arise in several problems of population dynamics, flame propagation and others. In one dimensional cases the systems may evolve into travelling fronts. Here we concentrate on a reaction diffusion equation which arises as a simple model for chemotaxis and present results for the speed of the travelling fronts. (Author)

  11. Analysis of the On the Spot (OTS) Road Accident Database

    Mansfield, H.; Bunting, A.; Martens, M.; Horst, A.R.A. van der

    2008-01-01

    The UK Government is seeking to substantially reduce the number of road traffic accidents (RTAs) leading to injury or loss of life. Specifically, relative to the average figures for 1994–98, the Government would like to meet the following road casualty reduction targets by 2010: • a 40% reduction in

  12. EFFECT OT KUNNU-ZAKI ON CLINICAL BACTERIAL ISOLATES

    omidiji

    2012-03-08

    Mar 8, 2012 ... S. aureus. 14. -. -. -. 12.5 ... S. paratyphi. 13.5. 11.5 ... Wells were then cut with flame-sterilized size 3 cork-borer, followed .... Prevalence of S. aureus in meat samples ... drink (Kunnu-zaki): Effect of spices pH and temperature.

  13. Physical environment at school : treatments and perspectives / Loone Ots

    Ots, Loone

    2008-01-01

    Artiklis vaadeldakse füüsilise keskkonna määratlust nüüdisaja hariduse paradigmas. 20. sajandi mõtlejate seisukohti ja rakendusuuringute tulemusi füüsilise keskkonna üksikute elementide mõju kohta õpitulemustele. Kas virtuaalne õpikeskkond võib välja vahetada füüsilise

  14. Mozarti mõõtmed ehk lavastajate kool / Loone Ots

    Ots, Loone, 1965-

    2010-01-01

    17. oktoobril Rahvusooperis Estonia esietendunud Mozarti koomilisest ooperist "Cosi fan tutte ossia La scuola degli amanti", lavastaja Walter Sutcliffe, etenduse muusikaline juht ja dirigent Arvo Volmer

  15. Ot Gannibala do "Russkogo bunta" / Tatjana Mühlbeier

    Mühlbeier, Tatjana

    2000-01-01

    Eestis elanud legendaarsest A. Pushkini vaarisast Abram Hannibalist ja temaga seoses ka sama ajastut kujutavast vene režissööri Aleksandr Proshkini uuest ajaloolisest mängufilmist "Vene mäss" ("Russki bunt")

  16. Ot Tallsinki do Hellinna 80 km / Aleksandr Kulakov

    Kulakov, Aleksandr

    2005-01-01

    23. kuni 25. septembrini toimus Helsingis Soome noorteühenduse TOK poolt korraldatud meediaseminar, kus osalesid vene keelt kõnelevad noored Eestist ja Soomest, ajakirjanikud ja noortega töötavad spetsialistid. Seminari eesmärgiks oli luua kontakte noorte ja vanemate loomeinimeste vahel ning leida võimalusi informatsiooni vahetamiseks ja koostöö arendamiseks erinevates riikides elavate venekeelsete noorte vahel

  17. COGORT METHOD AND OTS APPLICATIONS TO INSURANCE STATICTICS

    Yu. F. Kasimov

    2014-01-01

    Full Text Available The paper considers the so-called cohort method of accounting aggregates insurance portfolios. In insurance statistics systematization and processing of aggregate data on the issued policies, premiums and insurance payments are often made with gross errors, because ones don't set the criteria written policies and related payments to the analyzed statistical universe. Besides, it is often not clearly specify the scheme of calculation of aggregate statistical associated with these policies. The study gives a detailed and rigorous presentation as a method of formation of different cohorts data for a specified period of assessment the aggregated characteristics and methods of calculation of interest to insurance of indicators (absolute and relative for these cohorts. The knowledge of these methods is necessary for a correct assessment of insurance premiums and reserves.

  18. Veiko Õunpuu polutshit premiju ot ES

    2008-01-01

    Cannes'i filmifestivali raames toimuval Euroopa päeval antakse filmirežissöör Veiko Õunpuule üle Euroopa Talendi auhind (European Talent Prize) mängufilmiprojekti "Püha Tõnu Kiusamine" eest (produtsent Katrin Kissa)

  19. Report: Ozone Transport Commission Incurred Costs Under EPA Assistance Agreements XA98379901, OT83098301, XA97318101, and OT83264901

    Report #2007-4-00068, July 31, 2007. We questioned $2,723,706 of the $9,042,706 in reported outlays because the recipient claimed unallowable outlays for contractual services, indirect costs, and in-kind costs.

  20. Regularities in the Changes of Absorber Material Properties as a Function of Absorber Concentration; Regularite des Variations des Proprietes des Substances Absorbantes en Fonction de la Concentration de l'Absorbant; Zakonomernosti izmeneniya svojstv poglashchayushchikh materialov v zavisimosti ot kontsentratsii poglotitelya; Leyes de Variacion de las Propiedades de los Materiales Absorbentes en Funcion de la Concentracion del Absorbente

    Portnoj, K. I.

    1964-06-15

    pouvoir absorbant, en tant que fonction de la concentration de l'absorbant, varie d'apres une courbe caracteristique d'un phenomene de saturation et depend du spectre de neutrons. L'auteur formule une hypothese sur l'obtention du pouvoir absorbant maximum grace a la combinaison de plusieurs absorbants. Cette hypothese a ete largement confirmee par des experiences effectuees, dans des reacteurs a neutrons thermiques et intermediaires, sur de nombreuses combinaisons d'absorbants metalliques ou non. (author) [Spanish] En esta memoria se exponen las leyes que rigen las variaciones de las propiedades mecanicas y termofisicas y del poder de absorcion, en funcion de la concentracion del absorbente, en aleaciones destinadas a los reactores de neutrones termicos e intermedios. La conductividad y el coeficiente de dilatacion termica de las aleaciones absorbentes a base de boro y oxidos de las tierras raras se reducen al aumentar dicha concentracion. En el caso de las aleaciones con oxidos de las tierras raras, la variacion del coeficiente de dilatacion es lineal, mientras que para las alea,- ciones de boro esa caracteristica aditiva se altera. Ello se debe a que a temperaturas elevadas se forman fases de boruro con distintas redes cristalinas. En cuanto al poder absorbente, varia segun una curva de saturacion y depende tambien del espectro neutronico. El autor propone una hipotesis para explicar la aparicion de un maximo en la curva del poder absorbente, que atribuye a un fenomeno de interaleacion de los absorbentes. Esta hipotesis ha sido confirmada ampliamente por los resultados de experimentos efectuados con muchos sistemas absorbentes metalicos y no metalicos, de variada composicion, en reactores de neutrones termicos e intermedios. (author) [Russian] Doklad stavit cel'ju izlozhit' poluchennye zakonomernosti izmenenija mehanicheskih i teplofizicheskih svojstv, a takzhe pogloshhajushhej sposobnosti v zavisimosti ot koncentracii poglotitelej v sp lav a h , prednaznachennyh dlja

  1. Negotiating the rules of chaste behaviour : re-interpretations of the symbolic complex of virginity by young women of Moroccan descent in The Netherlands

    Buitelaar, M.W.

    This article investigates what narrations on the symbolic complex of virginity in the life-stories of second-generation women of Moroccan descent in The Netherlands can tell us about the ways these women construct, maintain and combine their various social identifications. It is demonstrated that

  2. "Moor, she was chaste, she loved thee, cruel Moor". 'Othello' as a starting point for alternative dramatic representations of the female voice

    Coporaal, M

    2002-01-01

    The common association between woman's speech and wantonness which dominated cultural discourses in Renaissance England, marked the representation of female characters in most Jacobean tragedies. As will be shown in this paper, William Shakespeare's "Othello" marks an important breach with the

  3. Geographic Information Systems in Developing Countries – What are the Ethical Issues we need to be aware of ? / Geografické Informační Systémy A Jejich Využití V Rozvojových Zemích - Jakým Etickým Otázkám Musíme Čelit?

    Pánek Jiří

    2013-06-01

    Full Text Available Využití geografických informačních systémů (GIS v rozvojových zemích se musí potýkat s historickou skepsí, kterou mapy, jako nástroj moci, mají mezi původními obyvateli. Participativní přístupy v mapování a GIS se snaží přistupovat k místním prostorovým znalostem s větší mírou společenské a etické zodpovědnosti. Článek se soustředí na popis vybraných důvodů, které vedly ke skeptickému postoji vůči GIS, a na identifikaci základních etických otázek sběru a interpretace prostorových informací v rozvojových zemích na příkladu mapování vodních zdrojů ve vesnici Koffiekraal v Jihoafrické republice.

  4. Strain Dependence of the Frequencies and the Thermal Expansion of the Hexagonal Close-Packed Lattice; Variations, en Fonction de la Deformation, des Frequences et de la Dilatation Thermique du Reseau a Structure Hexagonale Compacte; Zavisimost' chastot i teplovogo rasshireniya geksagonal'noj reshetki s plotnoj upakovkoj ot napryazheniya; Variacion de las Frecuencias y de la Dilatacion Termica de la Red Hexagonal Compacta en Funcion de la Deformacion

    Srinivasan, R.; Ramji Rao, R. [Physics Department, Indian Institute of Technology, Madras (India)

    1965-04-15

    {gamma}'' Para tres pares de valores de m y n. Se ha comprobado que {gamma}' = {gamma}'' y que el limite superior de temperatura {gamma}{sub {infinity}} mayor en 0,3, aproximadamente, que el limite inferior de temperatura{sup .} Esta diferencia cuya magnitud parece ser independiente de los valores de m y n, disminuira probablemente al tener en cuenta la interaccion de atomos vecinos mas alejados. Los datos teoricos se comparan con los resultados experimentales obtenidos en el caso del magnesio. (author) [Russian] Nedavno bylo izmereno anizotropnoe teplo voe rasshirenie nekotoryh geksagonal'nyh metallov. Dlja razrabotki teorii anizotropnogo teplovogo rasshirenija geksagonal'noj reshetki s plotnoj upakovkoj neobhodimo issledovat' zavisimost' chastot geksagonal'noj reshetki s plotnoj upakovkoj ot naprjazhenija. Rassmatrivalas' geksagonal'naja reshetka s plotnoj upakovkoj s central'nym vzaimodejstviem s bli- a b zhajshim sosednim atomom v vide Empty-Set = -a/{gamma}{sup m} + b/{gamma}{sup n} Ispol'zuemymi naprjazhenijami javljajutsja 1) prodol'noe rasshirenie #Greek Lunate Epsilon Symbol#' vdol' osi z; i 2) ravnomernoe vozdushnoe rasshirenie {zeta} vdol' osnovnoj ploskosti. Oni javljajutsja sootvetstvujushhimi naprjazhenijami v teorii teplovogo rasshirenija,i ih preimushhestvom javljaetsja to, chto oni ne vyzyvajut smeshhenij mezhdu reshetkami. Byli razrabotany parametry Grjunajzena {gamma}'{sub i} = - Partial-Differential log{omega}{sub i}/ Partial-Differential #Greek Lunate Epsilon Symbol#' and {gamma}'{sub i}' = - Partial-Differential log{omega}{sub i}/ Partial-Differential {zeta} Dlja volnovyh vekto- J rov, idushhih vdol' opredelennyh simmetrichnyh napravlenij. Bylo ustanovleno, chto jeti parametry dlja akusticheskih vetvej sil'no zavisjat ot napravlenija i sil'no kolebljutsja. Odna iz poperechnyh akusticheskih vetvej v osnovnoj ploskosti imeet otricatel'noe znachenie {gamma}' dlja ljubyh znachenij ship. Byla opredelena zavisimost' momentov {mu}{sub 2}, {mu}{sub 4} i {mu

  5. [Epidemiological study of intestinal helminthiasis in the island of Tortuga (Haiti). II. Evaluation of the parasite count by means of the Kato method].

    Raccurt, C; Vial, P; Pierre-Louis, J M

    1977-01-01

    Results of the numbering of T. trichiura, A. lumbricoides et N. americanus eggs found in the stool, taken from a representative sample of the population of Tortuga island, shows the importance of parasital load borne by people attacked by the parasites. Those who produce the greatest number of eggs for a gram of faeces are young children. For adults, the evolution of the parasital load follow that of the prevalence, for each Nematodes, with an increase of the average number of eggs of A. lumbricoides per gram of faeces for adults aged 30 to 44, and of the average number of N. amercanus per gram of faeces for adults aged 45 to 59. Moreover women adults show a higher number of parasites than men. Farmers from villages within the interior of the island who are more often attacked than those from the coast, also bear a parasital load which is twice as high. Victims less than 5 years old and more than 30, particularly women, whose faeces are richest in eggs, seem to present the greatest danger for the transmission of ascaridiosis and necatorosis in Toruga Island.

  6. Zodpovídání otázek dotazníkového průzkumu: interpretace otázky

    Vinopal, Jiří

    2007-01-01

    Roč. 5, č. 1 (2007), s. 10-14 ISSN 1214-438X R&D Projects: GA AV ČR IAA700280702 Institutional research plan: CEZ:AV0Z70280505 Keywords : Public Opinion * Question Interpretation * Poll Survey Methodology Subject RIV: AO - Sociology, Demography

  7. Ot ritualnite žertvi kăm răčenicata v minižupi (Etnomuzikovedski impresii ot Bălgarija)

    Tyllner, Lubomír

    2015-01-01

    Roč. 41, č. 4 (2015), s. 523-536 ISSN 0323-9861 Institutional support: RVO:68378076 Keywords : ethnomusicology * bulgarian folklore tradition * folk dance * traditional music * music al instruments Subject RIV: AC - Archeology, Anthropology, Ethnology

  8. Investigations of the chemical states of carrier-free phosphorus-32 as extracted into water from pile-irradiated sulphur; Recherches sur les etats chimiques du phosphore-32 sans entraineur obtenu par extraction aqueuse a partir de soufre irradie dans un reacteur; Issledovanie khimicheskogo sostoyaniya svobodnogo ot nositelya fosfora-32 pri izvlechenii ego v vodu iz obluchennoj v yadernom reaktore sery; Estudio de los estados quimicos del fosforo-32 libre de portador que se obtiene por extraccion acuosa del azufre irradiado en un reactor

    Dahl, J B; Birkelund, O R [Institutt for Atomenergi, Kjeller, Lillestrom (Norway)

    1962-01-15

    {>=} 5). Aucun metaphosphate (cyclique) n'a ete decele dans la solution lors de la production et du stockage. Les resultats indiquent que les composes de polyphosphore ont ete formes dans le materiau de cible au cours de l'irradiation. On a etudie plus particulierement l'adsorption des composes du phosphore-32 sans entraineur par le verre dans les conditions de l'experience. (author) [Spanish] Uno de los metodos que se emplean para obtener fosforo-32 libre de portador consiste en irradiar azufre en un reactor y extraer con agua el fosforo formado. La presente memoria informa sobre los estados quimicos del fosforo-32 en soluciones acuosas durante las diversas fases del proceso normal de obtencion. Los autores han estudiado tambien las modificaciones que el estado quimico de los compuestos de fosforo-32 experimenta en el producto final, en funcion del tiempo de almacenamiento. Han encontrado que el fosforo-32 aparece principalmente en forma de orto-fosfato. La proporcion de ortofosfato aumenta durante el tratamiento quimico; al comenzar la extraccion, es del orden del 70 por ciento, en tanto que alrededor del 98 por ciento del fosforo-32 libre de portador obtenido como producto final se encuentra bajo forma de ortofosfato. Los componentes restantes de la mezcla consisten en piro-, tri-, tetra- y polifosfatos de cadena larga (con un numero de atomos de fosforo {>=} 5). Durante la elaboracion y almacenamiento los autores no han encontrado metafosfatos (ciclicos) en ninguna de las soluciones. Los resultados obtenidos indican que los compuestos polifosforicos se formaron en el material del blanco durante la irradiacion. Los autores han prestado especial atencion al estudio de la adsorcion de compuestos de fosforo-32 libre de portador por el material de vidrio en las condiciones experimentales. (author) [Russian] Odnim iz sovremennykh metodov polucheniya svobodnogo ot nositelya fosfora-32 yavlyaetsya izvlechenie ego v vodu iz obluchennoj v yader- nom reaktore sery. V

  9. Chapter VII. The oxidation of ethylene line glycerin and of dihydro pyranol. A. General part(theoretical); Glava VII. Okislenie glitserinov etilenovogo ryada i digidropiranolov. A. Obshaya chast'(teoreticheskaya)

    Nikitin, V I

    1961-07-01

    In this chapter of book author made conclusion that off-peak compounds obligatory will oxidize above all with breach on place of off-peak connection are incorrect against to off-peak compounds, in which unsaturated carbons connected with oxygen containing carbons.

  10. Inglihääled vaiksel ööl / Loone Ots

    Ots, Loone, 1965-

    2015-01-01

    Jõululaulust "Püha öö" ("Vaikne öö"), sõnade autor Joseph Franz Mohr, viisi autor Franz Xaver Gruber. Jõulukoraalist "Hõisake, taevad", autor Joachim Neander. Jõulukoraalist "Ma tulen taevast ülevalt", autor Martin Luther

  11. Ajakirja Siluett kasvatuslikust rollist ilmumise esimesel viisaastakul (1958-1963) / Loone Ots

    Ots, Loone, 1965-

    2003-01-01

    Analüüsitakse kasvatuslikku rolli pealtnäha moeajakirjas, kuid väljaanne võttis ette moe kõrval ka naiseliku naise taasloomise, vahepeal põluall olnud käitumisnormide, hügieeniharjumuste, maitseka riietumisstiili jt. juba unustatud tarkuste õpetamise, mille abil naine kujuneb harmooniliseks isiksuseks

  12. Tants ei küsi vanust / Ille Grün-Ots, Siiri Rebane

    Grün-Ots, Ille, 1960-2016

    2007-01-01

    Kanal 2 menusaate "Tantsud tähtedega" järellainetuses vesteldakse artiklis seltskonnatantsust Revalia tantsukooli juhataja Merle Klandorfiga, bailatinost Dance Act direktori Georg Kodusaarega, kõhutantsust tantsuõpetaja Diana Otsinguga ja flamenkost Claudia Shevsthenkoga

  13. OT2_tvelusam_4: Probing Galactic Spiral Arm Tangencies with [CII

    Velusamy, T.

    2011-09-01

    We propose to use the unique viewing geometry of the Galactic spiral arm tangents , which provide an ideal environment for studying the effects of density waves on spiral structure. We propose a well-sampled map of the[C II] 1.9 THz line emission along a 15-degree longitude region across the Norma-3kpc arm tangential, which includes the edge of the Perseus Arm. The COBE-FIRAS instrument observed the strongest [C II] and [N II] emission along these spiral arm tangencies.. The Herschel Open Time Key Project Galactic Observations of Terahertz C+ (GOT C+), also detects the strongest [CII] emission near these spiral arm tangential directions in its sparsely sampled HIFI survey of [CII] in the Galactic plane survey. The [C II] 158-micron line is the strongest infrared line emitted by the ISM and is an excellent tracer and probe of both the diffuse gases in the cold neutral medium (CNM) and the warm ionized medium (WIM). Furthermore, as demonstrated in the GOTC+ results, [C II] is an efficient tracer of the dark H2 gas in the ISM that is not traced by CO or HI observations. Thus, taking advantage of the long path lengths through the spiral arm across the tangencies, we can use the [C II] emission to trace and characterize the diffuse atomic and ionized gas as well as the diffuse H2 molecular gas in cloud transitions from HI to H2 and C+ to C and CO, throughout the ISM. The main goal of our proposal is to use the well sampled (at arcmin scale) [C II] to study these gas components of the ISM in the spiral-arm, and inter-arm regions, to constrain models of the spiral structure and to understand the influence of spiral density waves on the Galactic gas and the dynamical interaction between the different components. The proposed HIFI observations will consist of OTF 15 degree longitude scans and one 2-degree latitude scan sampled every 40arcsec across the Norma- 3kpc Perseus Spiral tangency.

  14. Kolmas Nobeli füüsikapreemia elektronõrga vastastikmõju uurijatele / Ilmar Ots

    Ots, Ilmar

    2001-01-01

    1999. a. füüsikapreemia pälvisid hollandi teadlased Gerardus 't Hooft ja Martinus J. G. Veltman tööde eest elektronõrga vastastikmõju valdkonnas. Ettekanne 30. Eesti füüsikapäevadel : Tartu, 2000

  15. Füüsiline keskkond koolis : käsitlusi ja perspektiive / Loone Ots

    Ots, Loone

    2007-01-01

    Artiklis vaadeldakse füüsilise keskkonna määratlust nüüdisaja hariduse paradigmas. 20. sajandi mõtlejate seisukohti ja rakendusuuringute tulemusi füüsilise keskkonna üksikute elementide mõju kohta õpitulemustele. Kas virtuaalne õpikeskkond võib välja vahetada füüsilise

  16. Ot "Printsessõ Alissii" k "Hrabromu Rikki-Tikki-Tavi" / Eteri Kekelidze

    Kekelidze, Eteri, 1944-

    2000-01-01

    Tallinna muusikateater Väike Ooper jõudis tagasi Moskva külalisetendustelt, kus Eesti Saatkonnas esitati Boriss Kisseljovi lasteooper ""Printsess Alicia". Sügisel valmistub lasteteater lavale tooma helilooja uut ooperit "Julge Rikki-Tikki- Taavi"

  17. Husserl a otázka tělesnosti jako jádra subjektivity

    Novotný, Karel

    2015-01-01

    Roč. 63, mimořádné číslo 1 (2015), s. 51-60 ISSN 0015-1831 R&D Projects: GA ČR(CZ) GAP401/10/1164 Institutional support: RVO:67985955 Keywords : Inner Consciousness * Kinesthesis * Pure I * Self * Body * Lived Experience Subject RIV: AA - Philosophy ; Religion

  18. Hanna-Liina ja Dave Benton laulavad koos armastuslaule / Ille Grün-Ots

    Grün-Ots, Ille, 1960-2016

    2005-01-01

    Vanemuises L. Bernsteini muusikalis "West Side Story" laulvast Hanna-Liina Võsast, heliplaadist "Premi'ere", kontsertidest koos Dave Bentoniga 4. märtsil Saku mõisas, 6. märtsil Sangaste lossis ja 25. veebr. Ammende villas Pärnus

  19. Dave Bentoni jõulud lauluga / Ille Grün-Ots

    Grün-Ots, Ille, 1960-2016

    2004-01-01

    Poplaulja Dave Bentoni arvamusi jõulutraditsioonidest. Jõulutuurist Tallinnas Viimsi kultuurimajas 10. dets.ja Kaarli kirikus 11. dets., Pärnu Eliisabeti kirikus 15. dets., Kuressaare Laurentiuse kirikus 16. dets, Rapla Maarja-Magdaleena kirikus 19. dets., Tartu Peetri kirikus 20. dets., Oleviste kirikus Tallinnas 21. dets., Haapsalu Toomkirikus 22. dets., Jõelähtme kirikus 23. detsembril

  20. 3ot;kbt;sp•.t;kings , Eook Rt;~it;ws

    As 'n oud-militere het 'Noggs.' in 1879 die. Anglo-Zoeloeoorlog as 'n spesiale korespon- dent van die Londense Standard beskryf, ter- wyl hy in 1880-1881 iets dergeliks beoog het. Aan sy oorspronklike gedagte om die verloop van die eerste Anglo-Boereoorlog aan Boere- kant waar te neem en te beskryf, kon hy as.

  1. Increased radiosensitivity of a subpopulation ot T-lymphocyte progenitors from patients with Fanconi's anemia

    Knox, S.J.; Wilson, F.D.; Greenberg, B.R.; Shifrine, M.; Rosenblatt, L.S.; Reeves, J.D.; Misra, H.

    1981-01-01

    In vitro radiation survival of peripheral blood T lymphocytes was studied in 15 clinically normal adults and 4 patients with Fanconi's anemia. Tritiated thymidine incorporation in a whole blood lymphocyte stimulation test (LST) and a newly developed whole blood T-lymphocyte colony assay were used to measure lymphocyte blastogenesis and colony formation in response to phytohemagglutinin (PHA) or concanavalin-A (Con-A) stimulation. Lymphocyte colony formation was found to be consistently more sensitive than the LST for detection of low-level radiation effects using both normal cells and lymphocytes from Fanconi's anemia patients. Lymphocytes from patients with Fanconi's anemia were significantly more sensitive to in vitro x-irradiation than lymphocytes from clinically normal individuals as measured by their ability to divide when stimulated by PHA in the LST (patients, D37 . 198 R; normals, D37 . 309 R, p . 0.057) and colony formation assay (patients, D37 . 53 R; normals, D37 . 109 R, p . 0.016). No significant difference in the radiosensitivity of the Con-A response was observed between the two groups. The PHA-responsive T-lymphocyte subpopulation in Fanconi's anemia patients appears to be intrinsically defective. The nature of this defect, significance in the disease process, and relevancy of these findings to the establishment of radiation protection standards are discussed

  2. Lateral sellar compartment O.T. (cavernous sinus): history, anatomy, terminology.

    Parkinson, D

    1998-08-01

    Claudios Galen (119-199 a.d.) dissected lower animals with parasellar carotid retia bathed in venous blood and transposed his findings to human anatomy. Andreas Vesalius (1514-1564) corrected most of Galen's errors but apparently never looked into this small, extradural compartment, nor, apparently, did Winslow (Exposition Anatomique de la Structure du Corps Humain. London: N. Prevast, 1734), who christened it the "cavernous sinus," (CS) presumably thinking that it would resemble the corpora cavernosa of the penis. Multiple surgical explorations, gross dissections, microscopic views, and vascular casts from early fetuses to an 81 year old have been examined and reviewed. The CS is not a dural sinus nor is it cavernous. The compartment is extradural, and the venous structures contained within consist of a greatly variable plexus of extremely thin-walled veins. The name, CS, is a barrier to the understanding of the structure and function of this extradural anatomical jewel box, which contains fat, myelinated and nonmyelinated nerves, arteries, and a plexus of veins. It is proposed that this name be changed, because it is inaccurate and misleading. The replacement should leave no doubt about its meaning. The lateral sellar compartment is descriptive and accurate. The veins within are a parasellar plexus.

  3. The occurrence of pesticides in groundwater under consideration of diffuse inputs ot total herbicides

    Skark, C.; Zullei-Seibert, N.

    1994-01-01

    In a research project supported by the Environmental protection Agency (Umweltbundesamt) of the FRG we studied the connection between pesticide utilization and pesticide occurrence in groundwater in 58 examples of waterworks. Two thirds of all water sampling points considered were dominated by groundwater and most of these wells were built in porous aquifers. In other sampling points surface water or water which was dominated by artificial recharge of surfacewater of bankfiltration was analysed for pesticides. Independent of the sampling point character 5% of all single substance tests showed the occurrence of pesticides. Atrazine, desethylatrazine and simazine were detected with a frequency exceeding the average occurrence. The herbicides diuron and bromacil could be measured at least with an average frequency, indicating that the application of both substances in water protection areas may cause water quality problems. (orig.) [de

  4. Start-up ettevõtja kapitali kaasamist lihtsustavad äriseadustiku muudatused / Maivi Ots

    Ots, Maivi, 1974-

    2015-01-01

    20. novembril 2014 Vabariigi Valitsuse poolt Riigikogule menetlemiseks saadetud äriseadustiku muutmise seaduse eelnõust, mille kavandatavad muudatused võimaldavad osaühingutel kapitali lihtsamalt kaasata

  5. Royal Policy and the Transfer ot the Consulado under the Old Regime

    Allan J. KUETHE

    2017-11-01

    Full Text Available The abrupt transfer of the Casa de la Contratación and the Consulado de Cargadores a Indias from Seville to Cádiz in 1717 opened a political struggle between the two cities that would not be completely resolved until the enlightened absolutism of the Marqués de la Ensenada imposed its will. This struggle witnessed old regime politics at both their best and their worst. The present work seeks to analyze the several manifestations of this competition as well as the broader settings in which they occurred. While the new absolutism first appeared through the abad Alberoni in the original transfer and again through its affirmation by the duque de Ripperdá, with the hand of Queen Isabel not far beneath the surface, the traditional culture of consultation and compromise would eventually emerge and permit Seville to retain important powers until much later. Then, in a new era with much different priorities, which were heavily influenced by the coming of the War of the Asiento, royal absolutism as personified by Ensenada and his immediate predecessors would strip Sevilla of its remaining rights and at long last complete the transfer that had begun over twenty-six years before. 

  6. WHY DO THE ACUTE BEHAVIORAL EFFECTS OT TOLUENE IN RATS DEPEND ON THE ROUTE OF EXPOSURE?

    Despite evidence suggesting that the acute effects of organic solvents are related to their concentration in the brain, we have observed route-dependent differences in the acute behavioral effects of toluene. Whereas inhaled toluene disrupts the performance of rats on a visual si...

  7. 12 CFR 585.120 - What factors will OTS consider in reviewing my application?

    2010-01-01

    ... TREASURY PROHIBITED SERVICE AT SAVINGS AND LOAN HOLDING COMPANIES Exemptions § 585.120 What factors will... the savings and loan holding company; or (ii) Threaten the safety and soundness of any insured depository institution that is controlled by the savings and loan holding company, the interests of its...

  8. 3-Loop massive O(T2F) contributions to the DIS operator matrix element Agg

    Ablinger, J.; Schneider, C.; Bluemlein, J.; Freitas, A. de; Hasselhuhn, A.; Round, M.; Manteuffel, A. von

    2014-09-01

    Contributions to heavy flavour transition matrix elements in the variable flavour number scheme are considered at 3-loop order. In particular a calculation of the diagrams with two equal masses that contribute to the massive operator matrix element A (3) gg,Q is performed. In the Mellin space result one finds finite nested binomial sums. In x-space these sums correspond to iterated integrals over an alphabet containing also square-root valued letters.

  9. Logický čtverec a otázka existence

    Vlasáková, Marta

    2015-01-01

    Roč. 63, č. 1 (2015), s. 77-93 ISSN 0015-1831 R&D Projects: GA ČR(CZ) GA13-21076S Institutional support: RVO:67985955 Keywords : Aristotelian logic * square of opposition * existential import * existence as a second-order property Subject RIV: AA - Philosophy ; Religion

  10. 78 FR 76721 - Removal of Transferred OTS Regulations Regarding Recordkeeping and Confirmation Requirements for...

    2013-12-19

    ... in the preamble, the Board of Directors of the Federal Deposit Insurance Corporation revises part 344...; and (2) If the FDIC-supervised institution is to receive remuneration from the customer or any other source in connection with the transaction, a statement of the source and amount of any remuneration to be...

  11. Portrait of an OT artist: Using Mindfulness to find Life Balance

    Lydia Royeen

    2016-01-01

    Full Text Available Lynn Davies, a Canadian-based occupational therapist, understands the skill set and practice required to employ a balanced work/play/leisure routine, even for an occupational therapist. Occupational therapists can easily foster this balanced routine for clients; however, they may fall short of adopting this balanced routine in their own lives. Lynn uses art and mindfulness strategies to strive for a meaningful routine. Balancing her work as a therapist and her engagement in art is an ever-evolving orchestra, as she has a passion for both.

  12. Maaelu Eestis 1940.-1950. aastatel ajakirja Pilt ja Sõna materjalide põhjal / Loone Ots

    Ots, Loone, 1965-

    2007-01-01

    Maaelu kujutamisest ajakirja Pilt ja Sõna 1946., 1950. ja 1956. aasta numbrites. Erinevustest varanõukoguliku, tippstalinistliku ja poststalinistliku põllumajanduse käsitluste vahel, propaganda lõimumisest ajakirjas ilmunud materjalidega

  13. Development of a curriculum for OT students Learning about Intervention for Patients with COPD

    Larsen, Stina Meyer; Petersen, Anne Karin

    Et projekt med kobling af teori og praksis i perioden 2007-2009 med udvikling af konkret undervisningsforløb til ergoterapeutstuderende. Faserne i projektperioden var søgning af litteratur om kroniske lidelser, KOL og ergoterapi, dialog med ergoterapeuter i lokalmiljøet, udarbejdelse af studiefor...

  14. Zhenihh Balzaminov, skrõvajas ot svahh, zanimalsja jogoi / Oleg Peranov

    Peranov, Oleg

    2004-01-01

    Mängufilm Aleksandr Ostrovski teoste alusel "Balsaminovi abiellumine" ("Zhenitba Balzaminova") : stsenarist ja režissöör Konstantin Voinov : Nõukogude Liit 1964. Osavõtjate mälestusi filmi võtetelt

  15. Myths and the evolution ot science | Otu | Sophia: An African Journal ...

    The paper used the hermeneutic and analytical methods to x-ray the views of Claude Levi-Straus, Karl Popper, including the extremely complex knowledge of astronomy of the Dogon people of Mali to arrive at the conclusion that myths remain pivotal categories for the development of science especially for developing ...

  16. Ants Paju - philosopher in action / llle Grün-Ots

    Grün-Ots, Ille, 1960-2016

    2006-01-01

    Ants Paju on olnud Eesti Ülemnõukogu ja Riigikogu liige, Jõgeva linnapea ning aktiivne sportlane. Tema eestvõtmisel on Tallinn-Tartu maantee äärde rajatud Sõpruse park. Lisa: Park of Friendship

  17. Brand positioning strategies : an expiremental test ot two types of benefit differentiation

    Hem, Alexander Farestvedt; Teslo, Per Christian Strand

    2012-01-01

    The purpose of this study is to examine associative- and instrumental benefit differentiation based on secondary associations as part of brand positioning. The field of brand positioning has been subject to extensive research, however, differentiation based on secondary associations and differences between instrumental- and associative benefit differentiation has received less attention. Instrumental benefit differentiation relates to benefits that are linked directly to product performance, ...

  18. A re-examination of symmetry/Group relationships as applied ot the elementary particles

    Byrd, K.; Cole R.

    1993-01-01

    The purpose of this investigation is to apply Group Theory to the elementary particles. Group Theory is a mathematical discipline used to predict the existence of elementary particles by physicists. Perhaps, the most famous application of Group Theory to the elementary particles was by Murray Gell-Mann in 1964. Gell-Mann used the theory to predict the existence and characteristics of the then undiscovered Omega Minus Particle. Group Theory relies heavily on symmetry relationships and expresses them in terms of geometry. Existence and the characteristics of a logical intuitable, but unobserved member of a group are given by extrapolation of the geometric relationships and characteristics of the known members of the group. In this study, the Delta, Sigma, Chi and Omega baryons are used to illustrate how physicists apply geometry and symmetrical relationships to predict new particles. The author's hypothesis is that by using the D3 crystal symmetry group and Gell-Mann's baryons, three new particles will be predicted. The results of my new symmetry predicts the Omega 2, Omega 3, and Chi 3. However, the Chi 3 does not have characteristics consistent with those of the other known group members

  19. 78 FR 54403 - Removal of Transferred OTS Regulations Regarding Recordkeeping and Confirmation Requirements for...

    2013-09-04

    ...\\ The purpose of part 344 was two-fold: (1) To ensure that bank customers purchasing securities received... deposit account to purchase a security or securities, or any prearranged, automatic redemption or sale of..., administrator, guardian, or custodian under the Uniform Gifts to Minors Act; or (2) In a fund consisting solely...

  20. Deniel Kreig : Polutshiv rol Dzheimsa Bonda, ja napilsja ot stshastja! / Daniel Craig ; interv. Stass Tõrkin

    Craig, Daniel

    2006-01-01

    Ajakirjanikud Londonis uue Bondi-filmi "007: Casino Royale" esilinastusel ja pressikonverentsil. Näitleja Daniel Craig räägib endast, oma Bondi karakterist. Lisaks kõigi Bondi osatäitjate lühiandmed "Vse sekretnõje agentõ", kuulsaimad Bondi tüdrukud "7 samõh seksualnõh devushek agenta 007"

  1. Induction o.t labour with intravaginal misoprostol in the second and ...

    the discretion of the labour ward staff, oxytocin was used to augment labour. Otherwise, an intravenous drip was not routinely inserted. If the patient was not in labour within 12 hours of receiving the last dose of misoprostol, the treatment was considered a failure. Objective. To confirm the effectiveness of misoprostol as a.

  2. Routine evaluation ot arteriopathies of the lower extremities by digital subtraction angiography

    Stacul, F; Pozzi-Mucelli, R; Predonzan, F; Magnaldi, S; Abbona, M; Pozzi-Mucelli, R S; Dalla Palma, L

    1985-11-01

    Intravenous digital subtraction angiography (DSA) was performed in 119 patients with lower extremity ischemia using a 14'' amplifier. Four injections of contrast medium were usually necessary for a complete evaluation of this vascular region. Images of good quality were obtained in most cases; movement artifacts and a faint opacification accounted for any poor results, which occured mainly under the knee. The technique of pixel shifting turned out to be very useful to remove movement artifacts. The 'measuring field' allowed us to minimize the problem of the inhomogeneous saturation of the amplifier. In 8% of the cases an intra-arterial DSA has been performed after an unsatisfactory intravenous examination. Conventional angiography appears to be no longer necessary.

  3. Ursa Major: ot losya do medvedya %t Ursa Major: from elk to bear

    Lushnikova, A. V.

    In the article material from various cultural and linguistic sources (Indo-European - Slavic, Indo-Iranian; Uralo-Altaic, Tungus, Ancient Egyptian, Babylonian) is used in order to trace up the chronology of the designation of Ursa Majopr, a constellation which has been playing an important role for people different regions since ancient times. It was used for observing of the visible yearly motion of the Sun, for working out seasonal changes; being a circumpolar and non-hiding behind the horizon it has been perceived as a symbol of immortality, its peculiar positional change during a year lay down in plot of the Uralo-Siberian myths about a cosmic hunt for the Elk, myths about deluge. Data from Uralo-Siberian mythology are analyzed. Designations of Ursa Major in the form of a horned hoofed animal such as elk, deer, cow (Uralo-Altaic, Tungus, Slavic, Indo-Iranian languages; Ancient Greece, Crete, Ancient Egypt) and connected with it (or derived from it) denominations and images of "enclosed space" - "vehicle for travelling and carrying goods" (a wagon, a boat) - "instrument for hunting-fishing, a ritual thing" - "household construction" are taken in consideration. The conclusion is made that the transition of the Ursa Major designation from elk to bear could follow the general tendency to shift from so-called matriarchy to patriarchy, to substitute female deities with male ones, which was reflected "in the rise" of the predatory animal cults (not earlier than II mil. B.C.). To prove this, lexical examples of resemblance and coincidences in designation of homed hoofed (elk, deer) and predatory (bear, wolf) animals should be analyzed. Such a goal-directed investigation of the chronology of Ursa Major designations has never been carried out.

  4. Mõistetüübi ja informatsiooni organiseerimise viisi seotus probleemlahenduse edukusega / Aivar Ots

    Ots, Aivar

    2003-01-01

    Võimalike seoste analüüs erinevate mõistetüüpide kasutamise eelistamise ja informatsiooni organiseerimise viisi vahel. KVÜÕA-s välja töötatud õpikatse ja selle tulemuste tutvustamine. Graafikud

  5. OT2_amoor_4: A census of debris disks in nearby young moving groups with Herschel.

    Moór, A.

    2011-09-01

    Nearly all young stars harbour circumstellar disks, that serve as the reservoir for mass accretion onto the star, and later become the birthplace of planetary systems. After the disappearance of the gas component from the disk a dusty debris disk is formed that is believed to mark the location of the planetesimal belt as well. For outlining the evolution of such debris disks traditionally open clusters and field stars were studied, however we argue that the recently discovered young moving groups are more suitable objects for such analyses, due to their proximity and good coverage of the first 50 Myr period of the planetary system evolution. In this proposal we request 70/160 um Herschel/PACS photometric observations for so-far unobserved moving group members. These observations will provide a complete coverage of all known members within 80 pc of five nearby young moving groups (beta Pic Moving Group, Tucana-Horologium, Carina, Columba, and Argus), in the A to K spectral range. Based on the new observations we will identify new debris disks, characterize the disk population within individual moving groups, and study disk evolution by comparing the groups of different ages. The results will be used to verify predictions of the self-stirring model of the evolution of planetesimal disks. We will also compare the properties of debris disks in groups of the same age, looking for additional 'environmental' parameters that affect disk structure over a whole moving group. Our study will be a significant contribution to the census of debris disks in young moving groups, increasing the number of observed sources by a factor of 1.5. Since Spitzer could perform only a limited census and the so-far approved Herschel programs added very few additional moving group obervations, our programme is expected to have a high legacy value.

  6. Report on the Audit ot the Acquisition of the Tacit Rainbow Anti-Radiation Missile System

    1991-06-24

    This is our final report on the audit of the Tacit Rainbow Anti-Radiation Missile System (Tacit Rainbow) for your information and use. We performed... the audit from March through December 1990. The audit objective was to evaluate the acquisition management of the air-launched Tacit Rainbow system to...contains no recommendations because DoD took action to cancel the Tacit Rainbow system in FY 1992. We are bringing the issues identified during the audit to

  7. High-power extended cavity laser optimized for optical pumping ot Rb

    Buchta, Zdeněk; Číp, Ondřej; Lazar, Josef

    2007-01-01

    Roč. 18, č. 9 (2007), N77-N80 ISSN 0957-0233 R&D Pro jects: GA ČR GA102/04/2109; GA MŠk(CZ) LC06007; GA AV ČR IAA200650504; GA AV ČR IAA1065303 Institutional research plan: CEZ:AV0Z20650511 Keywords : laser diode * emission linewidth * diffraction grating * optical pumping * spectroscopy Subject RIV: BH - Optics, Masers, Lasers Impact factor: 1.297, year: 2007

  8. Kas Eesti muusikaõpetus vaevleb rahapuuduses? / Elin Ots ; interv. Kristel Kossar

    Ots, Elin

    2006-01-01

    Vestlusringis arutavad muusikaõpetajad ja haridusametnikud millised probleemid musikaharidust kimbutavad ja milliseid reforme see vajab. 17. novembril toimunud Eesti Muusikaõpetajate Liidu koolimuusika-alase konverentsi kaks väliskülalist prof. Franz Niermann ja Soili Perkiö avaldavad oma arvamust

  9. Portrait of an OT artist: Using Mindfulness to find Life Balance

    Lydia Royeen

    2016-01-01

    Lynn Davies, a Canadian-based occupational therapist, understands the skill set and practice required to employ a balanced work/play/leisure routine, even for an occupational therapist. Occupational therapists can easily foster this balanced routine for clients; however, they may fall short of adopting this balanced routine in their own lives. Lynn uses art and mindfulness strategies to strive for a meaningful routine. Balancing her work as a therapist and her engagement in art is an ever-evo...

  10. ICT and OTs: a model of information and communication technology acceptance and utilisation by occupational therapists.

    Schaper, Louise K; Pervan, Graham P

    2007-06-01

    There is evidence to suggest that health professionals are reluctant to accept and utilise information and communication technologies (ICT) and concern is growing within health informatics research that this is contributing to the lag in adoption and utilisation of ICT across the health sector. Technology acceptance research within the field of information systems has been limited in its application to health and there is a concurrent need to develop and gain empirical support for models of technology acceptance within health and to examine acceptance and utilisation issues amongst health professionals to improve the success of information system implementation in this arena. This paper outlines a project that examines ICT acceptance and utilisation by Australian occupational therapists. It describes the theoretical basis behind the development of a research model and the methodology being employed to empirically validate the model using substantial quantitative, qualitative and longitudinal data. Preliminary results from Phase II of the study are presented. The theoretical significance of this work is that it uses a thoroughly constructed research model, with potentially the largest sample size ever tested, to extend technology acceptance research into the health sector.

  11. Baltijskaja Evropa: ot idei k strategii [From the idea to the strategy of Baltic Europe

    Palmowski Tadeusz

    2009-01-01

    Full Text Available This article focuses on the historic prerequisites and forms of international cooperation in the Baltic region (“Baltic cooperation”. According to the author, Baltic Europe is being formed as a single administrative, economic, cultural and infrastructural area, which could become a new economic and cultural center of Europe. Special emphasis is given to policies and strategies of the EU in the Baltic Sea region.

  12. Scho d chara ots of ott) infe acteriz cocoy ected w zation yam

    SAM

    defen eins extracted fr. 1054 (Wi) and blotted on PVD specific for PR-3 extracted from th ose of their res s following SDS ased resistan. ,3-glucanase activity was ction. Я-1,3- essed in RO1 w accumulati. The low leve e tolerant c me may not h defense agai itinase in the yam at 8 dp nse-related in. Nyoche rom the roots of.

  13. OT1_ipascucc_1: Understanding the Origin of Transition Disks via Disk Mass Measurements

    Pascucci, I.

    2010-07-01

    Transition disks are a distinguished group of few Myr-old systems caught in the phase of dispersing their inner dust disk. Three different processes have been proposed to explain this inside-out clearing: grain growth, photoevaporation driven by the central star, and dynamical clearing by a forming giant planet. Which of these processes lead to a transition disk? Distinguishing between them requires the combined knowledge of stellar accretion rates and disk masses. We propose here to use 43.8 hours of PACS spectroscopy to detect the [OI] 63 micron emission line from a sample of 21 well-known transition disks with measured mass accretion rates. We will use this line, in combination with ancillary CO millimeter lines, to measure their gas disk mass. Because gas dominates the mass of protoplanetary disks our approach and choice of lines will enable us to trace the bulk of the disk mass that resides beyond tens of AU from young stars. Our program will quadruple the number of transition disks currently observed with Herschel in this setting and for which disk masses can be measured. We will then place the transition and the ~100 classical/non-transition disks of similar age (from the Herschel KP "Gas in Protoplanetary Systems") in the mass accretion rate-disk mass diagram with two main goals: 1) reveal which gaps have been created by grain growth, photoevaporation, or giant planet formation and 2) from the statistics, determine the main disk dispersal mechanism leading to a transition disk.

  14. The Transition from Spacecraft Development Ot Flight Operation: Human Factor Considerations

    Basilio, Ralph R.

    2000-01-01

    In the field of aeronautics and astronautics, a paradigm shift has been witnessed by those in academia, research and development, and private industry. Long development life cycles and the budgets to support such programs and projects has given way to aggressive task schedules and leaner resources to draw from all the while challenging assigned individuals to create and produce improved products of processes. however, this "faster, better, cheaper" concept cannot merely be applied to the design, development, and test of complex systems such as earth-orbiting of interplanetary robotic spacecraft. Full advantage is not possible without due consideration and application to mission operations planning and flight operations, Equally as important as the flight system, the mission operations system consisting of qualified personnel, ground hardware and software tools, and verified and validated operational processes, should also be regarded as a complex system requiring personnel to draw upon formal education, training, related experiences, and heuristic reasoning in engineering an effective and efficient system. Unquestionably, qualified personnel are the most important elements of a mission operations system. This paper examines the experiences of the Deep Space I Project, the first in a series of new technology in-flight validation missions sponsored by the United States National Aeronautics and Space Administration (NASA), specifically, in developing a subsystems analysis and technology validation team comprised of former spacecraft development personnel. Human factor considerations are investigated from initial concept/vision formulation; through operational process development; personnel test and training; to initial uplink product development and test support. Emphasis has been placed on challenges and applied or recommended solutions, so as to provide opportunities for future programs and projects to address and disposition potential issues and concerns as early as possible to reap the benefits associated with learning from other's past experiences.

  15. A parametric study ot protease production in batch and fed-batch cultures of Bacillus firmus.

    Moon, S H; Parulekar, S J

    1991-03-05

    Proteolytic enzymes produced by Bacillus species find a wide variety of applications in brewing, detergent, food, and leather industries. Owing to significant differences normally observed in culture conditions promoting cell growth and those promoting production of metabolites such as enzymes, for increased efficacy of bioreactor operations it is essential to identify these sets of conditions (including medium formulation). This study is focused on formulation of a semidefined medium that substantially enhances synthesis and secretion of an alkaline protease in batch cultures of Bacillus firmus NRS 783, a known superior producer of this enzyme. The series of experiments conducted to identify culture conditions that lead to improved protease production also enables investigation of the regulatory effects of important culture parameters including pH, dissolved oxygen, and concentrations of nitrogen and phosphorous sources and yeast extract in the medium on cell growth, synthesis and secretion of protease, and production of two major nonbiomass products, viz., acetic acid and ethanol. Cell growth and formation of the three nonbiomass products are hampered significantly under nitrogen, phosphorous, or oxygen limitation, with the cells being unable to grow in an oxygen-free environment. Improvement in protease production is achieved with respect to each culture parameter, leading in the process to 80% enhancement in protease activity over that attained using media reported in the literature. Results of a few fed-batch experiments with constant feed rate, conducted to examine possible enhancement in protease production and to further investigate repression of protease synthesis by excess of the principal carbon and nitrogen sources, are also discussed. The detailed investigation of stimulatory and repressory effects of simple and complex nutrients on protease production and metabolism of Bacillus firmus conducted in this study will provide useful guidelines for design of bioreactors for production of protease and bulk chemicals by this bacterium.

  16. Ot Karla Poppera do Karla Rouva i obratno / George Soros ; tõlk. Nikolai Zhdanovitsh

    Soros, George, 1930-

    2007-01-01

    USA on endiselt demokraatlik riik, kus juhindutakse põhiseadusest ja seaduse ülimuslikkuse printsiibist ning kus valitseb massiteabevahendite pluralism. Samas on ka ärevaid märke, mis viitavad totalitaalse režiimi propagandameetoditele

  17. Analysis of transient thermal behaviors during the charging process in stratified heat storage tanks. 2nd Report. Effects of characteristic parameters; Seiso chikunetsu sonai deno juten katei no kato netsuteki kyodo ni kansuru kaiseki. 2. Tokusei inshi no eikyo

    Yoo, H; Hong, H; Pak, E

    1997-11-25

    The mixing effect deteriorates performance in a stratified heat storage tank. In the present study, the effect of characteristic factors during the charging process was analyzed, based on the analytical solution in the previous study in which a strict boundary condition was applied and a mixing effect was included. Also, the usefulness of the solution was verified and the method of application to a real system was examined by comparing it to other experimental results. It was concluded that the depth of the perfectly mixed region is dominant unless the Peclet number is very small. 10 refs., 8 figs.

  18. Hot-wire air flow meter for gasoline fuel-injection system. Calculation of air mass in cylinder during transient condition; Gasoline funsha system yo no netsusenshiki kuki ryuryokei. Kato untenji no cylinder juten kukiryo no keisan

    Oyama, Y [Hitachi Car Engineering, Ltd., Tokyo (Japan); Nishimura, Y; Osuga, M; Yamauchi, T [Hitachi, Ltd., Tokyo (Japan)

    1997-10-01

    Air flow characteristics of hot-wire air flow meters for gasoline fuel-injection systems with supercharging and exhaust gas recycle during transient conditions were investigated to analyze a simple method for calculating air mass in cylinder. It was clarified that the air mass in cylinder could be calculated by compensating for the change of air mass in intake system by using aerodynamic models of intake system. 3 refs., 6 figs., 1 tab.

  19. Comparación de las técnicas Kato-Katz, TSET y TSR en el diagnóstico de infección por Fasciola hepatica en humanos

    Nelson Uribe Delgado; Raúl Fernando Sierra Balcárcel; Cindy Tatiana Espinosa González

    2012-01-01

    Introducción: La Fasciolosis es una enfermedad causada por el parásito Fasciola hepatica, que afecta primordialmente a bovinos, ovinos, caprinos y en algunas zonas de forma endémica a los humanos. En la investigación clínica y epidemiológica de fasciolosis humana es importante contar con técnicas coprológicas de diagnóstico de alta sensibilidad y especificidad. Objetivo: realizar la comparación de tres técnicas coprológicas para el diagnóstico de infección por Fasciola hepatica en humanos. Me...

  20. A radiation condition in some regions with more pronounced effect of the Chernobyl accident. Otnosno radiatsionnoto systoyanie v nyakoi rajoni s po-izrazeno vliyanie ot avariyata v Chernobil i ot AETS 'Kozloduj'

    Ivanov, I V; Ivanov, I M

    1993-01-01

    The radioecological condition of the Devin region situated in the Rodopes mountain (Bulgaria) has been investigated for the period October 1992 - March 1993. It is believed that the Rodopes were more significantly affected by the Chernobyl accident in comparison with other regions of Bulgaria. Some regions near Kozloduy NPP have been chosen for comparing, for which there are more detailed investigations of the anthropogenic radiation effects. Analysis of the background radiation is made, specific soil and water samples are tested. The alterations in the radiation conditions of the Devin region are analysed. Some conclusions and predictions for the trends in further alterations of the background radiation are made. As a result a draft regional program for environment protection reclamation is prepared. (V.K.).

  1. Kuppelkasvuhoonete disainer üllatab omapärase kunstnikukäega / Ille Grün-Ots

    Grün-Ots, Ille, 1960-2016

    2015-01-01

    Kanadas sündinud ja Pärnumaal Lindil elav eestlane Robert Mart Sermat ehitab erilisi kuppelkasvuhooneid ja teeb veel originaalsemat kunsti, mida sai näha näitusel „Heavy Metal” Endla teatri Sammassaalis 27. märtsist kuni 19. aprillini

  2. The first N-terminal unprotected (Gly-Aib)n peptide: H-Gly-Aib-Gly-Aib-OtBu.

    Gessmann, Renate; Brückner, Hans; Petratos, Kyriacos

    2015-12-01

    Glycine (Gly) is incorporated in roughly half of all known peptaibiotic (nonribosomally biosynthesized antibiotic peptides of fungal origin) sequences and is the residue with the greatest conformational flexibility. The conformational space of Aib (α-aminoisobutyric acid) is severely restricted by the second methyl group attached to the Cα atom. Most of the crystal structures containing Aib are N-terminal protected. Deprotection of the N- or C-terminus of peptides may alter the hydrogen-bonding scheme and/or the structure and may facilitate crystallization. The structure reported here for glycyl-α-aminoisobutyrylglycyl-α-aminoisobutyric acid tert-butyl ester, C16H30N4O5, describes the first N-terminal-unprotected (Gly-Aib)n peptide. The achiral peptide could form an intramolecular hydrogen bond between the C=O group of Gly1 and the N-H group of Aib4. This hydrogen bond is found in all tetrapeptides and N-terminal-protected tripeptides containing Aib, apart from one exception. In the present work, this hydrogen bond is not observed (N...O = 5.88 Å). Instead, every molecule is hydrogen bonded to six other symmetry-related molecules with a total of eight hydrogen bonds per molecule. The backbone conformation starts in the right-handed helical region (and the left-handed helical region for the inverted molecule) and reverses the screw sense in the last two residues.

  3. OT1_ebergin_5: A Systematic Survery of the Water D to H Ratio in Hot Molecular Cores

    Bergin, E.

    2010-07-01

    The D/H ratio of water and the enrichment of HDO relative to H2O in comets, oceans, and interstellar water vapor, has been posited as one of the primary links between chemistry in the cold (T = 10-20 K) dense interstellar medium (ISM) and chemistry in the Solar Nebula. However, there are only ~10 measurements of HDO/H2O, even in hot (T > 100 K) molecular cores, which have the most favorable chemistry (due to fossil evaporation of D-enriched ices) and excitation. In addition the existing measurements have a wide range of uncertainty, making it impossible to discern the presence of source-to-source variations, which could hint at the origin of deuterium enrichments in the dense ISM. We propose here to change this statistic with a systematic survey of HDO and H2O in a sample of 20 hot molecular cores spanning a two order of magnitude range in mass and luminosity. This will increase the number of known water D/H ratios by ~200%. This program is unique in scope for Herschel and requires the uniformity in calibration and high spectral resolution offered by the HIFI instrument. With the stability of HIFI we will be able to derive D/H ratios with significantly less uncertainty. Our observations will be combined with theoretical chemical models to explore the statistics offered by this sample. By looking at a large number of objects with a range of conditions we aim to unlock the secrets of water deuteration in the interstellar space.

  4. The jubilee year of the Estonian protocol was filled with extraordinary events / Ille Grün-Ots

    Grün-Ots, Ille, 1960-2016

    2006-01-01

    Eesti välisministeeriumi protokolliosakonna peadirektor Tiia Miller räägib organisatsioonilisest tööst tseremooniate ja riiklike visiitide korraldamisel, sealhulgas USA presidendi George W. Bushi ja Suurbritannia kuninganna Elizabeth II vastuvõtmisest. Juuresolevatel fotodel president Toomas Hendrik Ilves kõrgeid külalisi vastu võtmas

  5. Alkylation of gold surface by treatment with C18H37HgOTs and anodic Hg stripping

    Mucha, Malgorzata; Kaletová, Eva; Kohutová, Anna; Scholz, F.; Stensrud, Elizabeth; Stibor, Ivan; Pospíšil, Lubomír; Wrochem von, F.; Michl, Josef

    2013-01-01

    Roč. 135, č. 15 (2013), s. 5669-5677 ISSN 0002-7863 R&D Projects: GA ČR GA203/07/1619; GA ČR GA203/09/0705 EU Projects: European Commission(XE) 213382 - FUNMOL; European Commission(XE) 227756 - DIPOLAR ROTOR ARRAY Institutional support: RVO:61388963 ; RVO:61388955 Keywords : self-assembled monolayers * altitudinal molecular rotors * AU(111) * mercury Subject RIV: CC - Organic Chemistry Impact factor: 11.444, year: 2013

  6. Modeling the Operation of a Platoon of Amphibious Vehicles for Support of Operational Test and Evaluation (OT&E)

    Gaver, Donald

    2001-01-01

    ...) of the Marine Corps' prospective Advanced Amphibious Assault Vehicle (AAAV). The model's emphasis is on suitability issues such as Operational Availability in an on-land (after ocean transit) mission region...

  7. 75 FR 63107 - Alternatives to the Use of External Credit Ratings in the Regulations of the OTS

    2010-10-14

    ..., savings associations must consider the interest rate, credit, liquidity, price and other risks presented... subject only to moderate credit risk, and for whom expectations of default risk over the term of the... securities activities based on the levels and types of risks in its portfolio. As with the credit quality...

  8. Solar and artificial radiation: health effects and protective measures -- position statement and overview. (RSU 118/OT0799)

    NONE

    1999-08-16

    Sunburn is the skin's visible reaction to acute overexposure to ultraviolet radiation (UVR). It is estimated that in any given year there are about 3,150 new cases of malignant melanoma, the deadliest kind of skin cancer, and 64,000 new cases of non-melanoma skin cancers in Canada. Between 1986 and 1995 the age-standardized mortality of malignant melanoma increased by an annual average of 2.7 per cent among men and 1.7 per cent among women, the largest increase in mortality of all cancers in men and the second largest among women. This report provides a brief overview of the main characteristics, sources and health effects of ultraviolet radiation, along with a description of general protective measures and recommendations for specific settings. The expectation is that the document will help to promote sound UVR exposure reduction practices, and by so doing, help to reduce the negative health effects of overexposure to UVR among Canadians. The recommended protective measures include minimizing sun exposure (including exposure to sunlamps which are not considered a safe way to get a tan); seeking shade, especially from 11.00 AM to 4.00 PM; covering up; using a sunscreen with SPF 15 or higher that has both UV and UVB protection; and using lip and eye protection. Practising regular skin self-examination is also recommended.

  9. Crystal structure of product-bound complex of UDP-N-acetyl-D-mannosamine dehydrogenase from Pyrococcus horikoshii OT3

    Pampa, K.J., E-mail: sagarikakj@gmail.com [Department of Studies in Microbiology, University of Mysore, Mysore 570 006 (India); Lokanath, N.K. [Department of Studies in Physics, University of Mysore, Mysore 570 006 (India); Girish, T.U. [Department of General Surgery, JSS Medical College and Hospital, JSS University, Mysore 570 015 (India); Kunishima, N. [Advanced Protein Crystallography Research Group, RIKEN SPring-8 Center, Harima Institute, Hyogo 679-5148 (Japan); Rai, V.R. [Department of Studies in Microbiology, University of Mysore, Mysore 570 006 (India)

    2014-10-24

    Highlights: • Determined the structure of UDP-D-ManNAcADH to a resolution of 1.55 Å. • First complex structure of PhUDP-D-ManNAcADH with UDP-D-ManMAcA. • The monomeric structure consists of three distinct domains. • Cys258 acting as catalytic nucleophilic and Lys204 acts as acid/base catalyst. • Oligomeric state plays an important role for the catalytic function. - Abstract: UDP-N-acetyl-D-mannosamine dehydrogenase (UDP-D-ManNAcDH) belongs to UDP-glucose/GDP-mannose dehydrogenase family and catalyzes Uridine-diphospho-N-acetyl-D-mannosamine (UDP-D-ManNAc) to Uridine-diphospho-N-acetyl-D-mannosaminuronic acid (UDP-D-ManNAcA) through twofold oxidation of NAD{sup +}. In order to reveal the structural features of the Pyrococcus horikoshii UDP-D-ManNAcADH, we have determined the crystal structure of the product-bound enzyme by X-ray diffraction to resolution of 1.55 Å. The protomer folds into three distinct domains; nucleotide binding domain (NBD), substrate binding domain (SBD) and oligomerization domain (OD, involved in the dimerization). The clear electron density of the UDP-D-ManNAcA is observed and the residues binding are identified for the first time. Crystal structures reveal a tight dimeric polymer chains with product-bound in all the structures. The catalytic residues Cys258 and Lys204 are conserved. The Cys258 acts as catalytic nucleophile and Lys204 as acid/base catalyst. The product is directly interacts with residues Arg211, Thr249, Arg244, Gly255, Arg289, Lys319 and Arg398. In addition, the structural parameters responsible for thermostability and oligomerization of the three dimensional structure are analyzed.

  10. Quality of life of nursing-home residents with dementia subject ot surveillance technology versus physical restraints: an explorative study

    te Boekhorst, S.; Depla, M.F.I.A.; Francke, A.L.; Twisk, J.W.R.; Zwijsen, S.A.; Hertogh, C.M.P.M.

    2013-01-01

    Objective As physical restraints should only be used in exceptional cases, there is an urgent need for alternatives to restraint use. Surveillance technology could be such an alternative. This study explored whether nursing-home residents with dementia subjected to surveillance technology had better

  11. Multilocus phylogenetic analysis of true morels (Morchella) reveals high levels of endemics in Turkey relative ot other regions of Europe

    The present study was conducted to better understand how the phylogenetic diversity of true morels (Morchella) in Turkey compares with species found in other regions of the world. The current research builds on our recently published survey of 10 Turkish provinces and another of the world in which D...

  12. Od lovců k pastevcům: otázka neolitizace severovýchodní Afriky

    Suková, L.; Varadzin, Ladislav

    2013-01-01

    Roč. 15, č. 1 (2013), s. 25-31 ISSN 1213-1628 Institutional support: RVO:67985912 Keywords : Sudan * archaeology * Mesolithic * Neolithic * transition Subject RIV: AC - Archeology, Anthropology, Ethnology

  13. ICT & OTs: a model of information and communications technology acceptance and utilisation by occupational therapists (part 2).

    Schaper, Louise; Pervan, Graham

    2007-01-01

    The research reported in this paper describes the development, empirical validation and analysis of a model of technology acceptance by Australian occupational therapists. The study described involved the collection of quantitative data through a national survey. The theoretical significance of this work is that it uses a thoroughly constructed research model, with one of the largest sample sizes ever tested (n=1605), to extend technology acceptance research into the health sector. Results provide strong support for the model. This work reveals the complexity of the constructs and relationships that influence technology acceptance and highlights the need to include sociotechnical and system issues in studies of technology acceptance in healthcare to improve information system implementation success in this arena. The results of this study have practical and theoretical implications for health informaticians and researchers in the field of health informatics and information systems, tertiary educators, Commonwealth and State Governments and the allied health professions.

  14. A inesperada descoberta de Otávio Ianni sobre preconceito contra descendentes de imigrantes poloneses em Curitiba

    Márcio de Oliveira

    2015-12-01

    Full Text Available Resumo Após a pesquisa da Unesco sobre relações raciais no Brasil, Florestan Fernandes organizou e liderou uma jovem equipe para tratar do mesmo tema. A preferência recaiu então sobre os estados da Região Sul do Brasil, que não tinham feito parte da pesquisa original. Escolhidos por Florestan Fernandes, Fernando Henrique Cardoso, Roberto Jardim Moreira e Octávio Ianni fizeram parte dessa equipe. Na distribuição dos estados, coube a Ianni o Paraná e Santa Catarina, esse último conjuntamente com Fernando Henrique. Embora o objetivo da pesquisa fosse demonstrar a existência de preconceito nas relações raciais naqueles estados, Ianni ficou surpreso em descobrir também um novo preconceito, dessa feita contra imigrantes poloneses e seus descendentes, na cidade de Curitiba, capital do Paraná. Ianni investigou inicialmente a questão e publicou alguns artigos a respeito, nos quais tentou explicar o inesperado preconceito. No intuito de dar continuidade e investigar mais a fundo o fenômeno, elaborou e publicou um projeto de pesquisa sobre o tema que, contudo, nunca veio à luz.

  15. Informovanost dospívajících v otázce HIV/AIDS

    SOMPEKOVÁ, Zuzana

    2008-01-01

    Summary My bachelor work "The Knowing of Adolescents about HIV/AIDS" wants to find out how our adolescents are informed about HIV/AIDS and protection against sexual diseases, how they behave sexually, if they observe rules of safe sex and what they know about handling with potentially contaminated hypos. The theoretical part considers the role of family in sexual education and the role of parents in relation to sexual education. The next question is when and how to start with such education w...

  16. Projekt nastolující otázky : Dolf Seilacher a výstava Fossil Art. [Rozhovor

    Mikuláš, Radek; Seilacher, D. (A.)

    2008-01-01

    Roč. 4, č. 39 (2008), s. 8-8 ISSN 1801-4542. [Fossil Art. Krakow, 01.09.2008-01.11.2008] Institutional research plan: CEZ:AV0Z30130516 Keywords : fossils exhibition * Fossil Art, Krakow * science and art Subject RIV: DB - Geology ; Mineralogy

  17. K otázce etnické identity Rusínů v České republice

    Sulitka, Andrej

    2016-01-01

    Roč. 103, č. 3 (2016), s. 451-471 ISSN 0009-0794 Institutional support: RVO:68378076 Keywords : Ruthenian national minority in the Czech Republic * minoritarian associations in Prague * Ruthenian associations * minoritarian activities of the Ruthenians * self-identification of Ruthenians against Ukrainians * sources of Ruthenian identity Subject RIV: AC - Archeology, Anthropology, Ethnology

  18. Avtograf na Teodor Hagiopetrit ot C''rkovnija istoriko-arheologičeski Institut v Sofija, CIAI 949

    Džurova Aksinija

    2013-01-01

    Full Text Available Subject of this article is the copy of Four Gospels preserved at the Church Institute in Sofia (gr. 949, which was displayed in the Brilliance of Byzantium Exhibition organized during the 22nd International Congress of Byzantine Studies (August 22 - 27, 2011 and which we assumed to have been produced by the hand of one of the most famous scribes at the end of the 13th and the beginning of the 14th century, i.e. Theodore Hagiopetrites. The type of the script employed in the Four Gospels at the Church Institute (CHAI gr. 949 is in the so-called by L. Politis unique ‘Hagiopetrites Style’. Although the manuscript does not contain a colophon, comparison to the manuscripts of Theodore Hagiopetrites known to us and especially to Cod. D. gr. 29 (Olim. Kos. 35 at the Ivan Dujčev Centre - an autograph of the scribe of 1307, as well as to another manuscript from Saint Petersburg, Cod. gr. of ASUSSR, No 10/667 of the 14th century, provides good reasons to assume that the Four Gospels manuscript (CHAI gr. 949 was also produced by Theodore Hagiopetrites. Our certainty was further substantiated after we had studied in situ the Four Gospels from Academician N. P. Likhachev’s archive published by Igor Medvedev in the collection ‘ In Memoriam Ivan Dujčev’ of 1988 which is currently kept under No 10/667 in the Archive of the Leningrad Section of the Institute of History at the Russian Academy of Science. Having compared the illumination and the specifics of motif stylization, as well as the specific colouring, we could assert that the two manuscripts manifest pronounced similarities. Thereby, the 27 manuscripts by T. Hagiopetrites published by R. Nelson should also be supplemented by the Four Gospels at the Church Institute (CHAI gr. 949 in addition to the Apostle Lectionary of 1307, autograph of Theodore Hagiopetrites at the Dujčev Centre, Cod. D. gr. 29 (Olim. Kos. 35, which R. Nelson briefly mentioned in his preface, and the Saint Petersburg Four Gospels, published by I. Medvedev.

  19. Crystal structure of product-bound complex of UDP-N-acetyl-d-mannosamine dehydrogenase from Pyrococcus horikoshii OT3.

    Pampa, K J; Lokanath, N K; Girish, T U; Kunishima, N; Rai, V R

    2014-10-24

    UDP-N-acetyl-d-mannosamine dehydrogenase (UDP-d-ManNAcDH) belongs to UDP-glucose/GDP-mannose dehydrogenase family and catalyzes Uridine-diphospho-N-acetyl-d-mannosamine (UDP-d-ManNAc) to Uridine-diphospho-N-acetyl-d-mannosaminuronic acid (UDP-d-ManNAcA) through twofold oxidation of NAD(+). In order to reveal the structural features of the Pyrococcus horikoshii UDP-d-ManNAcADH, we have determined the crystal structure of the product-bound enzyme by X-ray diffraction to resolution of 1.55Å. The protomer folds into three distinct domains; nucleotide binding domain (NBD), substrate binding domain (SBD) and oligomerization domain (OD, involved in the dimerization). The clear electron density of the UDP-d-ManNAcA is observed and the residues binding are identified for the first time. Crystal structures reveal a tight dimeric polymer chains with product-bound in all the structures. The catalytic residues Cys258 and Lys204 are conserved. The Cys258 acts as catalytic nucleophile and Lys204 as acid/base catalyst. The product is directly interacts with residues Arg211, Thr249, Arg244, Gly255, Arg289, Lys319 and Arg398. In addition, the structural parameters responsible for thermostability and oligomerization of the three dimensional structure are analyzed. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Descartova ontologie mentální representace a otázka Suárezova vlivu

    Palkoska, Jan

    2010-01-01

    Roč. 7, č. 1 (2010), s. 28-48 ISSN 1214-8407 Institutional research plan: CEZ:AV0Z90090514 Keywords : Descartes * Suárez * mental representation * ontology * idea Subject RIV: AA - Philosophy ; Religion

  1. Learning in a Simulation-OT in Heart Surgery and the Challenges of the Scientification of Work

    Langemeyer, Ines

    2014-01-01

    Enhancing competency and collaboration has become a salient topic of the professional debate on medical safety issues. The advantages of simulation-based training scenarios for team communication, routines and critical work procedures especially in operation theatres have been vigorously discussed. However, the literature on simulation-based…

  2. Evropejskaja ideja v Central'noj Evrope i Skandinavii kak chast' politiki bezopasnosti i mirnogo sosushhestvovanija v ramkah poslevoennogo planirovanija [The European idea in Central Europe and Scandinavia as a part of the security and peaceful co-existence policy in the framework of the postwar planning

    Chernyshev Yevgeny

    2011-01-01

    Full Text Available This article is dedicated to the development of European unity in Central Europe and Scandinavia as a mechanism of collective security and intergovernmental cooperation development. The cultural and historical features of Central Europe and Scandinavia emphasize the need for a comparative study into the European idea. This article considers the tendencies and factors which affected the development of the European idea in the framework of the post-war planning. This research sets out to compare and identify similar or analogous features and elements of the theoretical bases of movements for European unity in Central and Northern Europe. The author comes to the conclusion about the correlation between the “Europe of regions” model and the European unity concept. The ideas of Scandinavian and Central European integration rested on national, cultural and historical connections of the neighbouring countries were expected to constitute such formations, which contradicted and were opposed to by the theoretical framework of Western European integration. On the other hand, regional integration implied that a federation or union of the neighbouring states could be considered a step towards a more universal organisation, which would not mean the isolation of Scandinavia and Central Europe from the rest of the world. The theoretical and practical significance of this work lies in the comparative approach to the analysis of the phenomena which have been considered individually in the framework of historiography. It is the major contribution of the article to the research on history of ideas and European diplomacy. Moreover, the subject of research is immediately connected to the problem of security in the Baltic region and the Soviet factor, as well as political stereotypes produced in this field. The author employed historical comparative and inductive types of the historical typological method.

  3. Legal and Administrative Problems of Controlling the Disposal of Nuclear Wastes in the Sea; Problemes Juridiques et Administratifs Poses par le Controle de l'Elimination des Dechets Nucleaires dans la Mer; 041f 0420 041e 0414 ; Problemas Juridicos y Administrativos que Plantea el Control de la Evacuacion de Desechos Nucleares En El Mar

    Hydeman, Lee M.; Berman, William H. [Atomic Energy Research Project, University of Michigan Law School (United States)

    1960-07-01

    control sobre una base tanto unilateral como multilateral. La ultima parte consiste en el examen de las diversas maneras de establecer un control internacional de la evacuacion en el mar de los desechos nucleares. La memoria hace referencia al papel de los organos internacionales existentes por lo que se refiere al ejercicio de un control administrativo permanente en el plano internacional. (author) [Russian] Osnovnoj cel'ju doklada javljaetsja predstavlenie nekotoryh podhodov k mezhgosudarstvennomu kontrolju za udaleniem radioaktivnyh othodov v morja kak s tochki zrenija primenenija samogo vida mezhdunarodnogo kontrolja, tak i s tochki zrenija sredstv po vypolneniju takogo kontrolja. Pervaja chast' predstavljaet soboj kratkoe opisanie kontrolja, neobhodimogo dlja ohrany zdorov'ja naselenija ot vlijanija radioaktivnyh othodov pri udalenii ih v morja. Vtoraja chast' sostoit iz obshhego analiza juridicheskih problem, voznikajushhih s osushhestvleniem udalenija radioaktivnyh othodov. Osobaja otvetstvennost' vozlagaetsja na gosudarstva, imejushhie morskuju granicu i osushhestvljajushhie odnostoronnij kontrol' po udaleniju othodov drugimi gosudarstvami, kotorye mogut nanosit' ushherb ih interesam. My issleduem sootvetstvie juridicheskih vozmeshhenij ubytkov ravno kak i vozmozhnogo zakona po predotvrashheniju ushherba, nanosimogo udaleniem radioaktivnyh othodov, i otvetstvennosti v sluchae nanesenija takogo ushherba. Tret'ja chast' doklada vkljuchaet analiz reshenija drugih problem kontrolja po odnostoronnemu i mnogostoronnemu soglashenijam. Poslednjaja chast' vkljuchaet issledovanie razlichnyh metodov mezhdunarodnogo kontrolja po udaleniju radioaktivnyh othodov v morja. V doklade upominaetsja rol' sushhestvujushhih mezhdunarodnyh organov po osushhestvleniju postojannogo administrativnogo kontrolja na mezhdunarodnom urovne. (author)

  4. Difference in Injury Mode, Dose-Rate Dependence and RBE of 730-Mev Protons, 100-KVp X-Rays and 250-KVp X-Rays; Differences dans le Type de Lesion, l'Importance du Debit de Dose et l'EBR entre les Protons de 730 Mev, les Rayons X de 100 Kv-Crete et les Rayons X de 250 Kv-Crete; Razlichiya kharaktera porazheniya, zavisimosti ot moshchnosti dozy i obeh protonov s ehnergiej 730 mehv i rentgenovskikh luchej s pikovym napryazheniem 100 i 250 kv; Diferencias en la Modalidad de La Lesion, la Relacion con la Intensidad de Dosis y la EBR de los Protones de 730 Mev, y los Rayos X de 100 Kvp Y de 250 Kvp

    Sondhaus, C. A.; Wallace, R. W.; Lyman, J. T.; Kase, K. W.; Steward, P. G. [University of California Lawrence Radiation Laboratory Berkeley (United States)

    1964-03-15

    pogibali na 12 -14-j den' v rezul'tate gemopojeticheskih narushenij, prichem obnaruzhena takaja zhe zavisimost' ot moshhnosti dozy. OBJe protonov po sravneniju s rentgenovskimi luchami s pikovym naprjazheniem 250 kv dlja LD{sub 50} k 30-mu dnju ravnjalas' 0,8; OBJe dlja LD{sub 50} k shestomu dnju ravnjalas' 1,2 pri toj zhe moshhnosti dozy 100 rad/min. Predpolagaetsja, chto razlichija v haraktere porazhenija mogu t byt' svjazany s neodinakovym raspredeleniem tkanevoj dozy. Bolee vysokaja, no izmenjajushhajasja OBJe protonov v otnoshenii kishechnoj smerti na shestoj den', ochevidno, javljaetsja projavleniem jeffekta moshhnosti dozy. Obsuzhdaetsja prakticheskoe znachenie faktorov raspredelenija dozy i ee moshhnosti. (author)

  5. Rwanda Journal - Vol 4, No 1 (2017)

    Julienne Murererehe, Peace Uwambaye, Moses Isyagi, Theogene Nyandwi, Kato Njunwa, 39-47 ... Peace Uwambaye, Kato Njunwa, Assouman Nuhu, Anne Kumurenzi, Moses Isyagi, Julienne Murererehe, Donart ... Current Issue Atom logo

  6. Diplomatický protokol a praktické otázky obchodní etikety v USA

    Vojtíšková, Aneta

    2010-01-01

    This thesis focuses on issues of business etiquette and diplomatic protocol of the United States of America. The aim is to provide deeper information in the field of business protocol and social contact. The first chapter describes specific characteristics of American culture and its influences on business negotiation. The second chapter defines selected issues of social and business etiquette. The third chapter is devoted to diplomatic protocol and diplomatic practice of the United States of...

  7. Raně scholastické univerzálie formulace a transformace otázky v 11. století (tzv. vokalismus a Anselm z Canterbury)

    Otisk, Marek

    2012-01-01

    Roč. 9, Supp.1 (2012), s. 32-47 ISSN 1214-8407 Institutional support: RVO:67985955 Keywords : vocalismus * John Roscellinus of Compiègne * Anselm of Canterbury Subject RIV: AA - Philosophy ; Religion

  8. K některým otázkám etnochoreologického studia: tanec, gender a politika

    Stavělová, Daniela

    2010-01-01

    Roč. 20, č. 4 (2010), s. 239-243 ISSN 0862-8351 Institutional research plan: CEZ:AV0Z90580513 Keywords : dance * gender * politics * national movement * identity Subject RIV: AC - Archeology, Anthropology, Ethnology

  9. Regeneración de palmas en plantaciones y bosques nativos en el santuario de fauna y flora Otún, Quimbaya (Risaralda, Colombia

    Diego Felipe Correa Gómez

    2006-01-01

    undata, Ch. pinnatifron y P. acuminata. En general, las clases plántulas y juveniles 1 contuvieron la mayor cantidad de individuos, con un máximo del 92% de total de individuos de G. undata encontrados en las urapaneras.

  10. Etika vědy a otázky národa v kontextu působení H. G. Schauera

    Drozenová, Wendy; Kučírek, Jiří

    2009-01-01

    Roč. 80, 3-4 (2009), s. 435-450 ISSN 1211-7617 R&D Projects: GA AV ČR(CZ) IAA900090803 Institutional research plan: CEZ:AV0Z90090514 Keywords : Czech traditions of ethics of science * H. G. Schauer * T. G. Masaryk Subject RIV: AA - Philosophy ; Religion

  11. Biblické citáty v apokryfních Otázkách Bartolomějových

    Chromá, Martina

    2016-01-01

    Roč. 85, 3-4 (2016), s. 287-302 ISSN 0037-6736 R&D Projects: GA MK DG16P02H024 Keywords : Questions of Bartholomew * Apocrypha * Old Church Slavonic Subject RIV: AI - Linguistics OBOR OECD: Specific languages

  12. A new determination of cross sections in methane and silane by using an exact method of solution ot the Boltzmann equation

    Segur, P.; Balaguer, J.P.

    1984-01-01

    We use a modified form of the SN method to solve the Boltzmann equation. We are then able to take into account the strong anisotropy of the distribution function which is known to occur in methane and silane. For a given set of cross-sections, the swarm parameters calculated with this method are very different from these published by previous authors (obtained with the standard two term Legendre expansion of the distribution function). The cross sections which we deduce by comparing experimental and calculated values for drift velocity and transversal diffusion coefficient are very different from these of Pollock or Duncan and Walker. With these two new sets of cross sections we make some calculations in mixtures of methane and silane, methane and argon, silane and argon. We note that our results for swarm parameters (at low E/N) are in good agreement with experimental values when they are available

  13. The marine cyanobacterium Crocosphaera watsonii WH8501 synthesizes the compatible solute trehalose by a laterally acquired OtsAB fusion protein

    Pade, N.; Compaoré, J.; Klähn, S.; Stal, L.J.; Hagemann, M.

    2012-01-01

    Compatible solutes are small organic molecules that are involved in the acclimation to various stresses such as temperature and salinity. Marine or moderate halotolerant cyanobacteria accumulate glucosylglycerol, while cyanobacteria with low salt tolerance (freshwater strains) usually accumulate

  14. Dependence of ferrocyanide preparation Bifezh efficiency on age peculiarities of cattle.; Zavisimost` ehffektivnosti ferrotsianidnogo preparata Bifezh ot vozrastnykh osobennostej krupnogo rogatogo skota.

    Gashchak, S P; Burov, N I; Arkhipov, N P [Nauchno-Proizvodstvennoe Ob` ` edinenie Pripyat` , Chernobyl (Ukraine)

    1994-12-31

    The aim of the experiment on cattle feeding a ration with high contents of {sup 137} Cs was to estimate an influence of age peculiarities on efficiency of ferrocyanide preparation Bifezh (a food additive). Data testifying to a decrease of the preparation efficiency with the age of calves are obtained. A sum of factors determining this regularity is analyzed.

  15. EPL-i ümarlaud : kõige olulisem on vähi varajane avastamine / Ille Grün-Ots

    Grün-Ots, Ille, 1960-2016

    2007-01-01

    Ümarlaual osalesid TÜ kliinikumi hematoloogia-onkoloogiakliiniku professor Hele Everaus, ravimifirma Roche Eesti OÜ tegevjuht Kadri Mägi, ravifirma GlaxoSmithKline Eesti filiaali juhataja Akshay Mody ja PERH-i keemiaravispetsialist Helis Pokker

  16. Tancova muzika v răkopisite na učitelja Irži Chartăl (1781–1849) ot Stara Paka

    Vejvoda, Zdeněk

    2015-01-01

    Roč. 41, č. 4 (2015), s. 491-512 ISSN 0323-9861 Institutional support: RVO:68378076 Keywords : folk dance * ethnomusicology * ethnochoreology * Jiří Hartl * music collections Subject RIV: AC - Archeology, Anthropology, Ethnology

  17. Subject and authorship of records related to the Organization for Tropical Studies (OTS) in BINABITROP, a comprehensive database about Costa Rican biology.

    Monge-Nájera, Julián; Nielsen-Muñoz, Vanessa; Azofeifa-Mora, Ana Beatriz

    2013-06-01

    BINABITROP is a bibliographical database of more than 38000 records about the ecosystems and organisms of Costa Rica. In contrast with commercial databases, such as Web of Knowledge and Scopus, which exclude most of the scientific journals published in tropical countries, BINABITROP is a comprehensive record of knowledge on the tropical ecosystems and organisms of Costa Rica. We analyzed its contents in three sites (La Selva, Palo Verde and Las Cruces) and recorded scientific field, taxonomic group and authorship. We found that most records dealt with ecology and systematics, and that most authors published only one article in the study period (1963-2011). Most research was published in four journals: Biotropica, Revista de Biología Tropical/ International Journal of Tropical Biology and Conservation, Zootaxa and Brenesia. This may be the first study of a such a comprehensive database for any case of tropical biology literature.

  18. Subject and authorship of records related to the Organization for Tropical Studies (OTS in BINABITROP, a comprehensive database about Costa Rican biology

    Julián Monge-Nájera

    2013-06-01

    Full Text Available BINABITROP is a bibliographical database of more than 38 000 records about the ecosystems and organisms of Costa Rica. In contrast with commercial databases, such as Web of Knowledge and Scopus, which exclude most of the scientific journals published in tropical countries, BINABITROP is a comprehensive record of knowledge on the tropical ecosystems and organisms of Costa Rica. We analyzed its contents in three sites (La Selva, Palo Verde and Las Cruces and recorded scientific field, taxonomic group and authorship. We found that most records dealt with ecology and systematics, and that most authors published only one article in the study period (1963-2011. Most research was published in four journals: Biotropica, Revista de Biología Tropical/ International Journal of Tropical Biology and Conservation, Zootaxa and Brenesia. This may be the first study of a such a comprehensive database for any case of tropical biology literature.

  19. Subject and authorship of records related to the Organization for Tropical Studies (OTS in BINABITROP, a comprehensive database about Costa Rican biology

    Julián Monge-Nájera

    2013-06-01

    Full Text Available BINABITROP is a bibliographical database of more than 38 000 records about the ecosystems and organisms of Costa Rica. In contrast with commercial databases, such as Web of Knowledge and Scopus, which exclude most of the scientific journals published in tropical countries, BINABITROP is a comprehensive record of knowledge on the tropical ecosystems and organisms of Costa Rica. We analyzed its contents in three sites (La Selva, Palo Verde and Las Cruces and recorded scientific field, taxonomic group and authorship. We found that most records dealt with ecology and systematics, and that most authors published only one article in the study period (1963-2011. Most research was published in four journals: Biotropica, Revista de Biología Tropical/ International Journal of Tropical Biology and Conservation, Zootaxa and Brenesia. This may be the first study of a such a comprehensive database for any case of tropical biology literature.BINABITROP es una base de datos bibliográfica con más de 38 000 registros sobre los ecosistemas y organismos de Costa Rica. En contraste con bases de datos comerciales como Web of Knowledge y Scopus, que excluyen a la mayoría de las revistas científicas publicadas en los países tropicales, BINABITROP registra casi por completo la literatura biológica sobre Costa Rica. Analizamos los registros de La Selva, Palo Verde y Las Cruces. Hallamos que la mayoría de los registros corresponden a estudios sobre ecología y sistemática; que la mayoría de los autores sólo registraron un artículo en el período de estudio (1963-2011 y que la mayoría de la investigación formalmente publicada apareció en cuatro revistas: Biotropica, Revista de Biología Tropical/International Journal of Tropical Biology, Zootaxa y Brenesia. Este parece ser el primer estudio de una base de datos integral sobre literatura de biología tropical.

  20. THOMAS STEARNS ELIOT AND OTTOMAN POETS IDEA UNION OTTOMAN POEM / THOMAS STEARNS ELİOT VE DİVAN SAİRİNİN ORTAK DÜNYASI

    Dr. Metin HAKVERDİOĞLU

    2009-04-01

    Full Text Available There is an idea and a method union betweenOttoman Poets and Thomas Stearn Eliot. Two differentworld man who contemplating unite a point for humanitythat is genostic human. Ottoman poets support Eliot’sspeech, Eliot says the world that Ottoman poets intimate before century. Our nation who has E. U. idealswill interest us to know these similar points. Becausethere are many thinker people there as us and ancetor.For these people, Eliot is a model both idea father andalso acknowledged man. The writer who was given Nobelreward is saying similar words as Ottoman poets’philosophy. In our duty, we know the past and researchseriously Eliot. It isnt’t possible astonish paralel opinionsabout culture, tradition, religion, philophy, literature.Having been pagan modern world against, it is a supportto Eliot from Ottoman poets before century.

  1. Otázky rukopisu Máchova Máje: K chystané kritické edici básně

    Charypar, Michal

    2017-01-01

    Roč. 65, č. 4 (2017), s. 540-564 ISSN 0009-0468 R&D Projects: GA ČR(CZ) GA16-02328S Institutional support: RVO:68378068 Keywords : textual criticism * Czech romantic poetry * 19th century * Mácha, Karel Hynek * critical hybrid edition * manuscript Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures

  2. Na jaké otázky odpovídali sociologičtí klasikové? - 1. část

    Simonová, Natalie

    2003-01-01

    Roč. 1, č. 4 (2003), s. 1 ISSN 1214-1720 Institutional research plan: CEZ:AV0Z7028912 Keywords : August Comte * Max Weber * beginning of sociology Subject RIV: AO - Sociology, Demography http://www.socioweb.cz

  3. Dependence of radiation effects in organic materials on absorbed dose rate; Zavisimost` radiatsionnykh ehffektov v organicheskikh materialakh ot moshchn osti pogloshchennoj dozy

    B` riksman, B A; Kras` ko, L B; Milinchuk, V K; Sichkar` , V P

    1994-12-31

    Analysis of experimental data on the dose rate effect on the operational properties of organic polymers is conducted. Methods of radiation effects forecasting under utilization of these materials are compared according to the results of the accelerated testing.

  4. [Characteristics of floor litter and soil arthropod community in different types ot subtropical forest in Ailao Mountain of Yunnan, Southwest China].

    Yang, Zhao; Yang, Xiao-Dong

    2011-11-01

    By using line transect method, an investigation was conducted on the floor litter and soil arthropod community in a mid mountain wet evergreen broad-leaved forest, a mossy dwarf forest, and a Populus bonatii forest in Ailao Mountain of Yunnan in April (dry and hot season), June (rainy season), and December (dry and cold season), 2005. In both dry and rainy seasons, the existing floor litter mass, C storage, and C/N ratio in the three forests all increased in the order of mossy dwarf forest > P. bonatii forest > evergreen broad-leaved forest, but the N storage had less difference. In the floor litter layer of the forests, Acari and Collembola were the dominant groups of soil arthropod community, while Diptera larvae, Coleoptera, ants, and Homoptera were the common groups. The Sorenson coefficients of soil arthropod community in the three forests were extremely great. No significant differences were observed in the soil arthropod density (ind x m(-2)) in the floor litter layer among the three forests, but the relative density (ind x g(-1)) of soil arthropods was higher in the evergreen broad-leaved forest and P. bonatii forest than in the mossy dwarf forest. In the three forests, the density of soil arthropods was significantly higher in dry season than in rainy season, but the Shannon diversity index had less difference. There were significant positive correlations between the existing floor litter mass and the individual density (ind x m(-2)) and dominant groups of soil arthropod communities in dry and hot season (April), but negative correlations between the existing floor litter mass and the relative density (ind x g(-1)) of soil arthropod communities and Acari in dry and cold season (December). The individual densities of Collembola and Coleoptera also had positive correlations with the N storage of the existing floor litter mass in the three forests. It was considered that the floor litter and the development of soil arthropod community in the litter layer of the subtropical forests in Ailao Mountain had a close relation with the vegetation structure of the forests, and the individual density and the diversity of the soil arthropod community were controlled by the floor litter, whereas the environmental factors such as temperature and moisture in the forests also had obvious effects on the seasonal dynamics of the individual density of the soil arthropods.

  5. Nová metoda kvantifikace otěrových částic UHMWPE v okolí kloubních náhrad

    Pokorný, D.; Šlouf, Miroslav; Dybal, Jiří; Zolotarevova, E.; Veselý, F.; Jahoda, D.; Vavřík, P.; Landor, I.; Entlicher, G.; Sosna, A.

    2009-01-01

    Roč. 76, č. 5 (2009), s. 374-381 ISSN 0001-5415 R&D Projects: GA MŠk 2B06096 Institutional research plan: CEZ:AV0Z40500505 Keywords : ultra high-molecular weight polyethylene * total hip arthroplasty * wear Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.628, year: 2009

  6. Metabolomic Analysis of Two Parmotrema Lichens: P. robustum (Degel. Hale and P. andinum (Mull. Arg. Hale Using UHPLC-ESI-OT-MS-MS

    Alfredo Torres-Benítez

    2017-10-01

    Full Text Available Lichens are symbiotic associations of fungi with microalgae and/or cyanobacteria. Lichens belonging to the Parmeliaceae family comprise 2700 species of lichens, including the Parmotrema genus which is composed of 300 species. The metabolites of this genus include depsides, depsidones, phenolics, polysaccharides, lipids, diphenylethers and dibenzofurans, which are responsible for the biological activities reported including antidiabetic, antihelmintic, anticancer, antioxidant, antibacterial, anti-inflammatory, antimitotic, antitumoral, antifungal, and antioxidant enzyme inhibitory. Due to scarce knowledge of metabolomic profiles of Parmotrema species (P. andinum and P. robustum, a full metabolome study based on ultra-high performance liquid chromatography- diode array detector-electrospray ionization-quadrupole-orbitrap-mass-spectrometry (UHPLC-DAD-ESI-Q-orbitrap MS was performed for a comprehensive characterization of their substances. From the methanolic extracts of these species, a total of 54 metabolites were identified for the first time using this hyphenated technique, including thirty compounds in P. andinum, and thirty-seven in P. robustum. Moreover, two compounds were not identified as known compounds, and could be new structures, according to our data. This report shows that this technique is effective and accurate for rapid chemical identification of lichen substances and the compounds identified could serve as chemotaxonomic markers to differentiate these ruffle lichens.

  7. Vanemliku hoolitsuseta jäänud laste perehoolde korraldamise õiguslikke probleeme : [bakalaureusetöö] / Ingrid Ots-Vaik ; Tartu Ülikool, õigusteaduskond ; juhendaja: Edgar Salumaa

    Ots-Vaik, Ingrid

    2000-01-01

    Lapse õigused ja lastekaitse süsteem Eestis, vanemliku hoolitsuseta jäänud lapse hoolekande korraldamise põhimõtted ja vormid, hoolduspere mõiste, leping lapse hooldamiseks ja kasvatamiseks, Eesti, Venemaa ja Soome hoolduslepingute võrdlev analüüs

  8. Cineradiography of the liquid bolus swallow. A study of the speed ot the bolus and peristaltic wave and of movement of the hyoid bone, larynx, and epiglottis

    Sundgren, P.

    1991-01-01

    In the evaluation of the dysphagic patient, radiology is crucial as a technique for monitoring morphology and function. In particular, high-speed cineradiography can reveal a variety of pharyngeal dysfunctions. However, in the literature and in practice the difference between normal and abnormal function is not always clear. This monography is based on high-speed cineradiographies of swallowing in 75 non-dysphagic volunteers and in 189 dysphagic patients. The purpose was to study whether differences in bolus volumes, patient position, age and gender had any effects on the following parameters: the speed of the peristaltic wave and apex of the liquid barium bolus, the length of movement and the movement pattern of the hyoid bone and larynx, and epiglottic function. The study disclosed that the speed of the bolus, the anterior-superior movement and net movement of the hyoid bone increased significantly with larger bolus volumes. The position of the individual in relation to gravity significantly influenced the speed of peristalsis. In most of the measured parameters there were no differences between non-dysphagic and dysphagic individuals expect for differences in the intrapersonal variations and in the anterior-superior movement of the hyoid bone. In patients with pharyngeal dysfunction the initial stage of the elevation of the larynx was significantly lower than in patients without dysfunction. The approximation of the thyroid cartilage to the hyoid bone was significantly greater in individuals with normal epiglottic function than in those with epiglottic dysmobility. It is suggested that abnormal speed of peristalsis may be a mild form of dysfunction. Measurements of the aforementioned speed and movements can be done if bolus volume, age and position of the patient, film speed and magnifications factors are known. Hypotheses concerning epiglottic function and central control of swallowing are proposed. (au)

  9. Meediavabaduse reguleerimine - allikakaitse ja vastulause õigus : [teadusmagistritöö] / Kristjan Ots ; Tartu Ülikool, sotsiaalteaduskond ; juhendaja: Halliki Harro-Loit

    Ots, Kristjan, 1976-

    2009-01-01

    Sisaldab ka varem ilmunud artikleid: Ajakirjandusvabadus ja allikakaitse. Juridica, 2005, nr. 8, lk. 571-583 ; Üksikisiku seisund meedia suhtes ning vastulause esitamise õigus. Juridica, 2008, nr. 2, lk. 102-118

  10. Otěr minerálních katalyzátorů ve fluidním zplyňovacím reaktoru

    Hartman, Miloslav; Svoboda, Karel; Pohořelý, Michael; Šyc, Michal

    2012-01-01

    Roč. 106, č. 9 (2012), s. 844-846 ISSN 0009-2770 R&D Projects: GA AV ČR IAA400720701 Grant - others:RFCR(XE) CT2010-00009 Institutional support: RVO:67985858 Keywords : gasification of biomass * catalyst attrition * dolomites and limestones Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 0.453, year: 2012

  11. Õpetaja professionaalse rolli internaliseerimise hindamine õpetajakoolituse esmaõppe üliõpilaste hulgas / Äli Leijen, Katrin Kullasepp, Aivar Ots

    Leijen, Äli, 1979-

    2013-01-01

    Aineõpetaja magistriõppe üliõpilaste seas läbi viidud uurimusest, milles vaadeldakse, kuidas üliõpilased koordineerivad personaalset ja professionaalset mina-positsiooni erialaste ambivalentsete olukordade kontekstis

  12. [Comparison of the cleansing effect of two micromotor-driven endodontic hand pieces. I. Comparison ot the cleansing effect of the two handpieces].

    Bartha, K; Rocca, J P

    1993-11-01

    The aim of the study was to assess the cleansing-effect of two endodontic handpieces (Excalibur, W & H; MM 1400 Micro Méga) in root canals that were previously manually prepared, and treated with chlor-(Neomagnol) and citric acid containing solutions. The analyses were performed by scanning electron microscope (SEM). The elimination of the Smear Layer (SL) with Neomagnol was not successful with either of the two handpieces. The cleansing of the Superficial Debris (SD) with Neomagnol activated by MM 1400 was significantly more effective in the apical (p < 0.05) and in the middle (p < 0.01) third of the root-canal, than by Excalibur. In contrast, SL was better eliminated by Excalibur using citric acid, significant differences--when compared with MM 1400--could be seen in the middle third (p < 0.05) of the root-canal. The handpieces seem to have their own specific characteristics: thus MM 1400 was better in eliminating the SD (used with Neomagnol), while Excalibur was superior in eliminating the SL (used with citric acid).

  13. ATTRIBUTION OF CONDUCT TO A STATE-THE SUBJECTIVE ELEMENT OF THE INTERNATIONAL RESPONSIBILITY OT THE STATE FOR INTERNATIONALLY WRONGFUL ACTS

    FELICIA MAXIM

    2012-05-01

    Full Text Available In order to establish responsibility of states for internationally wrongful act, two elements are identified. First, the conduct in question must be attributable to the State under international law. Secondly, for responsibility to attach to the act of the State, the conduct must constitute a breach of an international legal obligation in force for that State at that time. For particular conduct to be characterized as an internationally wrongful act, it must first be attributable to the State. The State is a real organized entity, a legal person with full authority to act under international law. But to recognize this is not to deny the elementary fact that the State cannot act of itself. States can act only by and through their agents and representatives. In determining what constitutes an organ of a State for the purposes of responsibility, the internal law and practice of each State are of prime importance. The structure of the State and the functions of its organs are not, in general, governed by international law. It is a matter for each State to decide how its administration is to be structured and which functions are to be assumed by government. But while the State remains free to determine its internal structure and functions through its own law and practice, international law has a distinct role. Conduct is thereby attributed to the State as a subject of international law and not as a subject of internal law. The State as a subject of international law is held responsible for the conduct of all the organs, instrumentalities and officials which form part of its organization and act in that capacity, whether or not they have separate legal personality under its internal law.

  14. K otázce tzv. akuzativního se v češtině: pohled (nejen) diachronní

    Pergler, Jiří

    2016-01-01

    Roč. 77, č. 2 (2016), s. 102-122 ISSN 0037-7031 R&D Projects: GA ČR(CZ) GA15-00987S Institutional support: RVO:68378092 Keywords : reflexive form * pronoun * morpheme * particle * categorization * diachrony * grammaticalization * Old Czech Subject RIV: AI - Linguistics Impact factor: 0.625, year: 2016

  15. A contribution ot the continued development of dry magnetic powder method for surface transverse crack testing of continuously casted semi-finished products

    Jaschke, D.H.

    1982-01-01

    The manifold of complex quality parameters is represented for the further development of a testing system. Selections and criteria for the industrial application and final testing are given and the process conditions are compared with plant possibilities by means of some examples. (orig.) [de

  16. 12 CFR 502.27 - How does OTS determine the risk/complexity component for a savings and loan holding company?

    2010-01-01

    ... holding company's financial condition, financial independence of the savings association and other affiliates that are regulated financial entities, operational independence of the savings association and other affiliates that are regulated financial entities, reputational risks raised by affiliation with...

  17. On the nature of anomalies in temperature dependence of the OKh18N1OT steel yield strength after thermal cycling in the low temperature range

    Medvedev, E.M.; Lavrent'ev, F.F.; Kurmanova, T.N.

    1978-01-01

    Investigated were structural transformations in 0Kh18N10T steel as a result of heating and cooling and of deformation within the range of temperatures between 300 and 77 K, the quantity relationships between the said transformations and the variation of the yield limit with the temperature. The studies were conducted by metallography and mechanical test methods. It was shown that an increase in the number of heating and cooling cycles correlates with a loss in strength of the steel while deformation at 77 K. This anomaly in the temperature relationship of the yield limit is related to the appearance in the course of deformation of α-martensite with a BCC lattice. Deformation at 300 K increases the amount ea of epsilon-martensite, a decrses the effectve size of grain and, in consequence, increases the yield limit. The relationship between the yield limit and the grain size at the temperature of 300 K is described adequately by the Hall-Petch equation

  18. György Lukács, otázky marxistické ortodoxie a český marxismus

    Landa, Ivan

    2017-01-01

    Roč. 1, č. 1 (2017), s. 39-48 ISSN 2570-7485 Institutional support: RVO:67985955 Keywords : Lukács * Dialetical Method * Totality * Kosík * Sochor * Dubský Subject RIV: AA - Philosophy ; Religion OBOR OECD: Philosophy, History and Philosophy of science and technology

  19. Joseph Knabenbauer SJ (1839–1911 a otázka evolučního vzniku člověka

    Ctirad V. Pospíšil

    2017-08-01

    Full Text Available The paper is a part of the research that focuses on the Catholic theologians and biologists between 1871 and 1910 who accepted Mivart’s thesis of the evolutionary origin of the human body, or who, on the contrary, tended to reject it. The paper presents J. Knabenbauer SJ (1839–1911. In the 1930s, Czech theologian J. Miklik asserted that Knabenauer accepted Mivart’s position. Knabenbauer’s study on evolution is analysed. Already in 1877, Knabenbauer shows, in the first two parts of his work, an openness to the reality of evolutionary origin of species in the fauna and flora. In the third part, he deals with Mivart’s thesis. From the philosophical point of view, Knabenbauer admits the possibility of the creation of human body by way of evolution. From the exegetical point of view, he refuses the reading of Gen 2:7 that considered this verse to be an allusion of the origin of the human body from the animal base. Because of this later view, Miklik’s information is to be considered imprecise. Knnabenbauer’s study contains, though, much relevant information that testifies to the Catholic theology and exegesis of his era.

  20. Právní otázky direct marketingových sdělení v České republice

    Demuthová, Martina

    2014-01-01

    The thesis deals with the issue of direct marketing, its instruments and related legislation. Direct marketing is a form of marketing communication which allows businesses to communicate directly with their customers. Its value in marketing is increasing, as well as spam, which is also defined in this thesis. First explained is the term direct marketing, its advantages and disadvantages, its tools and current role in the industry. Furthermore, a summary of the present legal and ethical regula...

  1. Zaniklé Otěchleby u Velké Bíteše (okr. Žďár nad Sázavou)

    Burešová, M.; Kirchner, Karel; Unger, J.; Roštínský, Pavel; Šedo, Ondrej; Velek, J.

    2013-01-01

    Roč. 65, č. 3 (2013), s. 301-305 ISSN 0323-2581 Institutional support: RVO:68145535 ; RVO:68081758 Keywords : defunct village * Middle Ages * Velká Bíteš Subject RIV: AC - Archeology, Anthropology, Ethnology

  2. K aktuálním otázkám správní vědy

    Grospič, Jiří

    -, č. 1 (2010), s. 23-35 ISSN 0323-0619 Institutional research plan: CEZ:AV0Z70680506 Keywords : public private partnership * administrative law * eGovernment * eGovernance Subject RIV: AG - Legal Sciences

  3. Õpilaste heaolu resilientsus ja mõistestruktuuri areng: erinevused kooliga rahulolu säilitamisel ebameeldivate koolikogemuste ja klassiõpetaja kasvatusstiili taustal / Aivar Ots

    Ots, Aivar

    2014-01-01

    Üle-eestilisest põhikooli õpilaste heaolu uuringust, mille eesmärgiks oli selgitada, kuidas erineb õpilaste võime säilitada koolis kogetavat heaolu, võttes arvesse nende kooliga seotud ebameeldivaid kogemusi ja kognitiivset arengut

  4. K otázce (ne)existence akuzativního se v současné češtině

    Veselý, Luboš

    2013-01-01

    Roč. 5, č. 4 (2013), s. 308-317 ISSN 1803-876X R&D Projects: GA ČR GA13-07138S Institutional support: RVO:68378092 Keywords : reflexive * word form se * accusative case * enclitics * pronoun Subject RIV: AI - Linguistics

  5. O vidu slovesa soustředit se (Příspěvek k otázce jazykové správnosti)

    Veselý, Luboš

    2011-01-01

    Roč. 94, č. 3 (2011), s. 134-141 ISSN 0027-8203 R&D Pro jects: GA ČR GAP406/11/2021 Institutional research plan: CEZ:AV0Z90610518 Keywords : linguistic correctness * prefixation * verbs * verbal aspect Subject RIV: AI - Linguistics

  6. „Čelakovský - ausserordentlich ruhig“. Otázka generací a loajalit v české politice

    Pavlíček, Tomáš W.

    2015-01-01

    Roč. 45, č. 1 (2015), s. 127-137 ISSN 0079-4929. [Formování vědního oboru národních právních dějin ve střední Evropě. Pocta prof. Jaromíru Čelakovskému (1846–1914). Praha, 04.11.2014-06.11.2014] Institutional support: RVO:67985921 Keywords : Čelakovský, Jaromír * political culture Subject RIV: AB - History

  7. Molitva o izbavlenii ot bluda v církevněslovanských rukopisech Trojicko-sergijevské lávry

    Čajka, František

    2013-01-01

    Roč. 82, 1-2 (2013), s. 43-52 ISSN 0037-6736 R&D Projects: GA ČR(CZ) GAP406/12/1790 Institutional support: RVO:68378017 Keywords : Old Church Slavonic * Church Slavonic * prayer * the Trinity Lavra of St. Sergius * manuscripts * Forty Gospel Homilies by Pope Gregory the Great Subject RIV: AI - Linguistics

  8. Uudised : Georg Ots 80. "Pärt in Profile" Londonis. Kaljuste taas esile tõstetud. Paavo Järvi eesti muusikaga La Scalas / Priit Kuusk

    Kuusk, Priit, 1938-

    2000-01-01

    G. Otsa 80. sünniaastapäeva tähistamisest G. Otsa nim. Tallinna Muusikakoolis ئ avati G. Otsa muuseum. 28.-31. märtsini Londonis toimuvast muusikafestivalist "Pärt in Profile", kus tutvustatakse A. Pärdi jt. eesti heliloojate loomingut. T. Kaljuste on Edison Classical Music Awards 2000 nominentide seas koorimuusika kategoorias kahel korral. P. Järvi juhatas 28. veebr. Milano La Scala orkestrit, kavas A. Pärdi "Cantus in memoriam Benjamin Britten", dirigendi tegemistest märtsis

  9. Provencance of the late Proterozoic to early Cambrian metaclastic sediments ot the Sierra de San Luis (Eastern Sierras Pampeanas) and Cordillera Oriental, Argentina

    Drobe, M.; López de Luchi, M.; Steenken, A.

    2009-01-01

    Provenance studies have been performed utilising major and trace elements, Nd systematics, whole rock Pb-Pb isotopes and zircon U/Pb SHRIMP data on metasedimentary rocks of the Sierra de San Luis (Nogolí Metamorphic Complex, Pringles Metamorphic Complex, Conlara Metamorphic Complex and San Luis...... is depicted for all the complexes using major and trace elements. The Pringles Metamorphic Complex shows indications for crustal recycling, pointing to a bimodal provenance. Major volcanic input has to be rejected due to Th/Sc, Y/Ni and Cr/V ratios for all units. The eNd(540 Ma) data is lower for the San Luis...... Formation and higher for the Conlara Metamorphic Complex, as compared to the other units, in which a good consistency is given. This is similar to the TDM ages, where the metapsammitic samples of the San Luis Formation are slightly older. The spread of data is largest for the Pringles Metamorphic Complex...

  10. Njakoi ot po-novite publikacii na Instituta za Češki nacionalen korpus za perioda 2010-2011 godina

    Uhlířová, L.; Nisheva, Bozhana

    2013-01-01

    Roč. 38, č. 1 (2013), s. 42-51 ISSN 0204-8701 Institutional support: RVO:68378017 Keywords : Institute of the Czech National Corpus * Czech and Bulgarian language of propaganda * totalitarian age Subject RIV: AI - Linguistics

  11. Design, synthesis and biological activity of new neurohypophyseal hormones analogues conformationally restricted in the N-terminal part of the molecule. Highly potent OT receptor antagonists

    Kwiatkowska, A.; Ptach, M.; Borovičková, Lenka; Slaninová, Jiřina; Lammek, B.; Prahl, A.

    2012-01-01

    Roč. 43, č. 2 (2012), s. 617-627 ISSN 0939-4451 Institutional research plan: CEZ:AV0Z40550506 Keywords : oxitocin antagonists * Atosiban * neurohypophyseal hormones analogues * arginine vasopressin (AVP) * antidiuretic hormone * binding affinity Subject RIV: CE - Biochemistry Impact factor: 3.914, year: 2012

  12. Horké vlny v měnícím se klimatu: otázky zůstávají

    Kyselý, Jan; Pecho, Jozef

    2012-01-01

    Roč. 91, - (2012), s. 28-34 ISSN 0042-4544 Institutional support: RVO:68378289 Keywords : heat waves * climate change * global warming * European heat waves 2003 * Czech Republic. Subject RIV: DG - Athmosphere Sciences, Meteorology http://www.vesmir.cz/obor/klimatologie

  13. Maret Maripuu : HIV-haigete raviks jätkub raha ka järgmisel aastal / Maret Maripuu ; interv. Ille Grün-Ots

    Maripuu, Maret, 1974-

    2008-01-01

    Sotsiaalministri Maret Maripuu sõnul leiab HIV-i vältimise vajalikkus üha rohkem kõlapinda kogu ühiskonnas ja poolele teele seisma jääda ei tohi. Kommenteerib Lääne-Tallinna Keskhaigla nakkuskeskuse juhataja Kai Zilmer

  14. NVGClient - Programový systém pro vizualizaci taktických dat ve 3D pro OTS VŘ PozS

    Přenosil Václav; Františ Petr; Hodický Jan; Havelka Ladislav

    2012-01-01

    Program NVGClient je určený k přenosu taktických průsvitek z webové služby dle standardu NATO NVG do použitého vizualizačního programu. Při přenosu taktických průsvitek dochází k rozdělení jednotlivých grafických elementů (taktických značek) do určených kategorií a rovněž dochází k převodu symbolů (taktických značek) v přenášených průsvitkách dle kódu APP6B do jeho grafické podoby. Zároveň jsou taktické značky jednotek doplněny informacemi z příslušné databáze o jejich stavu (množství pohonný...

  15. Sociální dimenze optimálního vývoje: Otázky a výzvy

    Millová, Katarína

    2016-01-01

    Roč. 60, Supplement 1 (2016), s. 76-85 ISSN 0009-062X R&D Projects: GA ČR GA15-22474S Institutional support: RVO:68081740 Keywords : optimal development * adaptive social functioning * longitudinal research Subject RIV: AN - Psychology Impact factor: 0.242, year: 2016

  16. Kulturismus a revoluce: K otázce sociálních dějin tělesnosti v Československu

    Šabek, Jiří

    2016-01-01

    The thesis tries to process a topic of bodybuilding phenomenon in the wider context of the ideal body formation in modern age. Bodybuilding is understood as a specific socio-cultural phenomenon closely tied to a modern society and its historical development. Beyond the bodybuilding the work also deals with an analysis of the contemporary social body theory with focus on the domestic discourse and subsequently also with an analysis of discursive formation modern physicality from the Enlightenm...

  17. K otázce provenience svrchnokarbonských slepenců v severovýchodních Čechách

    Mikuláš, Radek; Prouza, V.

    2008-01-01

    Roč. 2007, - (2008), s. 27-29 ISSN 0514-8057 R&D Projects: GA AV ČR IAA304130601 Institutional research plan: CEZ:AV0Z30130516 Keywords : Krkonoše Piedmont Basin * Intrasudetic Basin * Upper Carboniferous * Ordovician * Skolithos ichnofabric * conglomerates Subject RIV: DB - Geology ; Mineralogy http://www.geology.cz/zpravy/obsah/2007/2007-8.pdf

  18. Serbest Gezinmeli Sistemde Yem Formu ve Ot Varlığının Etlik Piliçlerde Performans Üzerine Etkileri

    Bahattin Koçer

    2017-09-01

    Full Text Available This study was designed to investigate the effect of feed form (mesh or pellet and vegetation cover (available or unavailable on the growth performance, some organ weights and carcass characteristics of slow growing broiler chickens reared in the free range system in a 2x2 factorial design. A total of 800, day-old slow-growing broiler chickens (Hubbard Isa Red-JA 87 were randomly allotted into 4 dietary treatments, and 4 replicates of 50 birds. The effect of feed form was much more pronounced than forage intake in terms of body weight gain and feed conversion ratio with significant improvements in favour of pellet feed form. Throughout the experimental periods of 25 to 48 and 49 to 72, chicks fed on pellet feed gained more body weight which accompanied to lower feed conversion ratio compared to those receiving mesh feed. Pellet feed decreased feed consumption of birds from 25 to 48 days as compared to birds fed with mesh feed. However, this tendency disappeared thereafter and no significant difference was found between treatments throughout the experimental periods. Carcass yield of broiler chicks slaughtered at 72 days of age was not significantly affected by either feed form or green grass intake during the outdoor access.

  19. Ludický princip v kontextu otázky po zdařilém životě

    Koubová, Alice

    2016-01-01

    Roč. 60, Suppl. 1 (2016), s. 31-40 ISSN 0009-062X R&D Projects: GA ČR(CZ) GJ16-00994Y Institutional support: RVO:67985955 Keywords : well-being * eudaimonia * ludic principle * play * game * ethics of virtues Subject RIV: AA - Philosophy ; Religion Impact factor: 0.242, year: 2016

  20. Measurement ot the switching over-voltages at the disconnection of the high voltage shunt reactors in the Romanian power system

    Stroica, Paul Constantin; Merfu, Ion; Stroica, Mihail; Merfu, Marius; Cojocaru, Florian; Stefan, Dinu; Cojocaru, Mihai

    2010-09-15

    The paper presents the measurements of the switching over-voltages made in the Romanian Power System, at the 400/220/110 kV Urechesti substation at the disconnection of a 400 kV, 100 MVAr shunt reactor type DFAL, Siemens, Germany, in 3 consecutive versions. The first one is for shunt reactor controlled by live-tank oil circuit breaker, the second one is for shunt reactor controlled by SF6 circuit breaker, and the third one is for shunt reactor controlled by SF6 circuit breaker and synchronize device.

  1. Herxheim - odpověď na otázku krizového vývoje na konci kultury s lineární keramikou?

    Končelová, Markéta

    Roč. 8, - ( 2007 ), s. 11-13 ISSN 1213-1628 Institutional research plan: CEZ:AV0Z80020508 Keywords : Herxheim * Linear Pottery culture * elliptical system of elongated pits * ritual practices Subject RIV: AC - Archeology, Anthropology, Ethnology

  2. 75 FR 42833 - Prohibited Service at Savings and Loan Holding Companies

    2010-07-22

    ....treas.gov . OTS will post comments and the related index on the OTS Internet Site at http://www.ots... regulations applicable to savings associations under Regulation DD. Regulation DD implements the Truth in...

  3. A New Population of Parvocellular Oxytocin Neurons Controlling Magnocellular Neuron Activity and Inflammatory Pain Processing.

    Eliava, Marina; Melchior, Meggane; Knobloch-Bollmann, H Sophie; Wahis, Jérôme; da Silva Gouveia, Miriam; Tang, Yan; Ciobanu, Alexandru Cristian; Triana Del Rio, Rodrigo; Roth, Lena C; Althammer, Ferdinand; Chavant, Virginie; Goumon, Yannick; Gruber, Tim; Petit-Demoulière, Nathalie; Busnelli, Marta; Chini, Bice; Tan, Linette L; Mitre, Mariela; Froemke, Robert C; Chao, Moses V; Giese, Günter; Sprengel, Rolf; Kuner, Rohini; Poisbeau, Pierrick; Seeburg, Peter H; Stoop, Ron; Charlet, Alexandre; Grinevich, Valery

    2016-03-16

    Oxytocin (OT) is a neuropeptide elaborated by the hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei. Magnocellular OT neurons of these nuclei innervate numerous forebrain regions and release OT into the blood from the posterior pituitary. The PVN also harbors parvocellular OT cells that project to the brainstem and spinal cord, but their function has not been directly assessed. Here, we identified a subset of approximately 30 parvocellular OT neurons, with collateral projections onto magnocellular OT neurons and neurons of deep layers of the spinal cord. Evoked OT release from these OT neurons suppresses nociception and promotes analgesia in an animal model of inflammatory pain. Our findings identify a new population of OT neurons that modulates nociception in a two tier process: (1) directly by release of OT from axons onto sensory spinal cord neurons and inhibiting their activity and (2) indirectly by stimulating OT release from SON neurons into the periphery. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Some factors influencing the absorption, retention and elimination of ruthenium; Facteurs agissant sur l'absorption, la retention et l'elimination du ruthenium; Nekotorye faktory, vliyakshchie na vsasyvanie, zaderzhku i vydelenie ruteniya; Factores que influyen sobre la absorcion, retencion y eliminacion de rutenio

    Bruce, R. S. [Radiobiological Research Council, Medical Research Council, Harwell (United Kingdom)

    1963-02-15

    'yu oporozhneniya zheludka i soedineniem' ruteniya s soderzhimym kishechnika. Vsasyvanie uvelichivaetsya v tri raza i prodolzhaetsya znachitel'no dol'she, esli rutenij vvoditsya krysam posle nochnogo golodaniya. Nitratoproizvodnye nitroehila ruteniya v protivopolozhnost' drugim issledovannym soedineniyam vstupayut v reaktsiyu so stenkoj verkhnego otdela tonkogo kishechnika, gde na neskol'ko chasov mozhet zaderzhivat'sya okolo 20% prinyatoj vnutr' dozy. Khotya stepen' vsasyvaniya zavisit ot khimicheskogo sostoyaniya ruteniya, ono ne vliyaet v zametnoj stepeni na posledukhiee raspredelenie ehlementa. Priblizitel'no polovina vsosavshegosya ruteniya vydelyaetsya s mochoj v techenie pervykh 24 chasov. Po istechenii mesyatsa zaderzhivaetsya ot 5 do 20% vsosav-shikhsya fraktsij s dlinnyj biologicheskim periodom poluraspada. Faktor raspredeleniya kontsentratsij ruteniya v razlichnykh organakh redko prevyshaet 5, khotya raspredelenie v odnoj i toj zhe tkani ne vsegda odinakovo. Naibolee vysoka kontsentratsiya v pochkakh, yavlyayuiikhsya glaznym putem vyvedeniya. Rassmotrenie povedeniya ruteniya v syvorotke krovi pomogaet ob{sup y}asnyat' protsessy ego raspredeleniya i zaderzhki. Esli smeshat' rutenij s syvorotkoj In vitro, to chast' ego prochno svyazyvaetsya s belkami; a chast' ostaetsya svobodnoj. Svobodnyj rutenij mozhet byt' obnaruzhen v syvorotke neposredstvenno posle vnutrivennogo vvedeniya ili prinyatiya vnutr', no bystro ischezaet. Vozmozhno, chto posle togo, kak rutenij vsasyvaetsya v svobodno diffundiruyushchej forme, chast' ego reagiruet s belkami syvorotki i pervonachal'no ostaetsya v sosudistom prostranstve, chast' nemedlenno vyvoditsya cherez pochki, a chast' bystro diffundiruet vo vnesosudietoe prostranstvo i tkani. Poslednyaya fraktsiya mozhet libo reagirovat' s tkan'yu i zaderzhivat'sya ili diffundirovat' obratno v krov' i vydelit'sya. CHerez neskol'ko dnej kontsentratsiya ruteniya v syvorotke snizhaetsya so skorost'yu, sootvetstvuyushchej skorosti degradatsii belkov

  5. Fulltext PDF

    him the gift to perform this task with ease. In one of his articles he speaks of his school science teacher Thirumalai Kozhunthu PiJJai, who en- thused the students by teaching science in an understandable way in chaste Tamil. Listening to him he got the conviction that difficult scientific concepts could be conveyed in Tamil.

  6. Learning Curves: Body Image and Female Sexuality in Young Adult Literature. Scarecrow Studies in Young Adult Literature #35

    Younger, Beth

    2009-01-01

    Adolescence is a time of growth, change, and confusion for young women. During this transition from childhood to adulthood, sex and gender roles become more important. Meanwhile, depictions of females--from the hyper-sexualized girls of music videos to the chaste repression of Purity Balls--send mixed messages to young women about their bodies…

  7. Potentials for Use of Medicinal Plants in Female Reproductive ...

    USER

    canadensis L.), and Chaste tree fruits (Vitex agnus- castus L.) are listed in the U. S. Pharmacopoeia and are available as dietary supplements to be used for premenstrual stress syndrome, as emmenagogue agents, and for gynaecological problems. Castor oil (Ricinus communis L.)18 and cotton bark root (Gossypium.

  8. Composition of the essential fruit oil of Vitex agnus-castus

    Zwaving, J.H; Bos, R.

    Vitex agnus-castus, the chaste tree, is used against disorders of the female sexual organs and as an anaphrodisiac. Active constituents are not known. In this study the essential oil of the fruits was investigated by GC and GC-MS.

  9. Bibliography of Soviet Laser Developments, Number 73, September - October 1984.

    1986-01-01

    construction of optical systems. Teoria si constructia sistemelor optice [in Romanian]. Bucuresti, Tehnica, 1982, 451 p. (RZFZA, 84/9L468). 850. Donchenko...Chast’ 2 . Sistema chastits. Tomsk, 1983, 184 p. (RZFZA, 84/10L78). 851. Galeyev, A.A.; Sudan, R.M. (eds). (. Fundamentals of plasma physics. Supplement

  10. Etické otázky vědy v reflexi Církve československé (husitské) od jejího vzniku v r.1920 do současnosti

    Lášek, Jan Blahoslav; Hrdlička, J.

    2008-01-01

    Roč. 79, 3-4 (2008), s. 440-478 ISSN 1211-7617 R&D Projects: GA AV ČR(CZ) IAA900090803 Institutional research plan: CEZ:AV0Z90090514 Keywords : Czechoslovak church * ethics Subject RIV: AA - Philosophy ; Religion

  11. Aktuální otázky adopce a výchovy dětí v homoparentálních rodinách

    Lásková, Hana

    2012-01-01

    Bachelor thesis, "Current issues of adoption and education of children in homoparenting families" deals with the issue of homosexuality, a registered partnership, the possibilities of parenthood homosexual couples and the education of children in homoparenting families. In the beginning of my work I deal with the definition of homosexuality, causes of its origin, history and contemporary perspective on homosexuality and gay live opinions. Next there is a chapter about registered partnership, ...

  12. Turkey's Struggle with Internet in its 3rd year: Don Quixote, Ostrich, Harakiri 3. Yılında Türkiye'nin İnternetle Savaşı: Donkişot, Devekuşu, Harakiri

    Mustafa Akgül

    2010-06-01

    Full Text Available The Code 5651 which sets Internet censhorship in Turkey has been active for 3 years. With this lawr, our country twanted to be a leader among democratic countries and challenged giant companies like Youtube and Google and fined them with tax penalty. Our country t is trying to set İnternational Law on Internet via code 5651 and decisions of its courts. But it doesn't do this by defending or negotiating the issue on international forums or United Nations. It considers Internet as media and it punishes and bans similar to printing press.. A serious number of people, including the Prime Minister, break the ban. The President of the Republic, State Minister for EU, Minister of Transportation and chairman of Information and Communication Technologies Authority give statements against these bans. In the meantime, rule of law, separation of powers, fair trial, and basic human rights such as freedom of expression are ignored. In other words, a Legal Tradegy occurs in front of lawyers and intellectuals. And our country commits hara-kiri by not understanding Internet, just like the situation in printing machine. In this article, various dimensions of the 3-year struggle of Turkey with Internet are discussed. Türkiye'de İnternet yasaklarını düzenleyen 5651 numaralı kanun çıkalı 3 yılı aştı. Bu kanunun çıkış sürecinde ve bugüne kadar uygulamasında, ülkemiz bir yandan dünyaya önderlik etmeye çalıştı, bir yandan Youtube/ Google gibi devlere meydan okudu; onlara büyük vergi cezaları kesti. Ülkemiz, kendi internet algılaması ve değerlendirmesini dünyaya empoze etmeye çalışıyor. Böylece, bu konuda, uluslararası hukuku tesis etmeye çalışıyor. Bunu, uluslararası forumlarda, Birleşmiş Milletlerde önererek, savunarak, müzakere ederek yapmıyor. İnterneti, basın gibi algılayarak, basına uygulanan yasaklama alışkanlıkları ile yasaklıyor. Başbakan dahil internet yasaklarını önemli bir çoğunluk deliyor. Bu yasaklara Cumhurbaşkanı, Avrupa Birliği’nden sorumlu Devlet Bakanı, hatta Ulaştırma Bakanı ve BTK (Bilgi Teknolojileri ve İletişim Kurumu Başkanı da karşı beyanlar veriyor. Bu arada Hukuk'un temel ilkeleri, kuvvetler ayrılığı, adil yargılama, özgürlüklerin özüne dokunulmaz ilkesi gözardı ediliyor. Bir başka deyişle, ülkenin hukukçuları ve düşünen insanların gözü önünde bir Hukuk Faciası yaşanıyor. Ve ülkemiz, matbaada olduğu gibi, interneti anlamayarak, harakiri yapıyor Bu yazıda, Türkiye'nin internetle savaşının 3 yıllık macerasının boyutları değerlendirecektir

  13. JETCAL 2000R Analyzer H337PA-603 Operational Test and Evaluation (OT&E) on H-53 E/J Aircraft and H46 D/E Aircraft

    2003-01-28

    Proposal Title PORTABLE TEST CELL - JETCAL 2000(R) Lead Proposer HOWELL INSTRUMENTS Military Customer NAVY/MARINE H53...B-4 Proposal Title PORTABLE TEST CELL - JETCAL 2000(R) Lead Proposer HOWELL INSTRUMENTS Military Customer...TEST CELL - JETCAL 2000(R) Lead Proposer HOWELL INSTRUMENTS Military Customer NAVY/MARINE H53 AIRCRAFT Baseline Costs -- DoD’s Costs When COSSI is NOT

  14. "Slušný" Bursík a "neslušný" Železný v Otázkách Václava Moravce

    Havlík, Martin

    -, 43/44 (2007), s. 33-68 ISSN 1211-5770 R&D Projects: GA ČR GA405/06/1468; GA AV ČR KJB900610701 Institutional research plan: CEZ:AV0Z90610518 Keywords : conversation analysis * turn-taking * sociolinguistics * language of politics Subject RIV: AI - Linguistics

  15. Příběh tří Mikulášů od Věže. Příspěvek k otázce jejich totožnosti

    Musílek, Martin

    2013-01-01

    Roč. 29, č. 1 (2013), s. 2-15 ISSN 0231-6056 R&D Projects: GA ČR(CZ) GAP405/11/1982 Institutional support: RVO:67985955 Keywords : Prague * Prague’s Old Town * Brno * Tišnov * town elite * town seals * town genealogy Subject RIV: AB - History

  16. Aktuální právní otázky odpovědnosti dopravce při námořní přepravě zboží

    Blahutová, Lenka

    2010-01-01

    in English The transport sector represents about 7% of European GDP. It should be also noted that European companies own 41% of the total world fleet capacity. As it can be seen, transport itself is an important industry and a major contributor to the functioning of not only the European economy but also the international economy. The maritime transport covers 80% of all trade exchange and has become the major transport sector in international business. The Hague, Hague-Visby (together so cal...

  17. K otázkám rétorické a empirické evidence v myšlení raného novověku

    Řezníková, Lenka

    2016-01-01

    Roč. 13, č. 2 (2016), s. 195-210 ISSN 1214-7249 R&D Projects: GA ČR GB14-37038G Institutional support: RVO:67985955 Keywords : Rhetorical Evidence * Early Modern Thought * J. A. Comenius Subject RIV: AB - History

  18. La toxoplasmose oculaire : immunopathologie et Virulence : l'influence de la virulence du parasite sur les caractéristiques cliniques, biologiques et immunologiques de la toxoplasmose oculaire (OT) de l'Ancien et du Nouveau monde

    De la Torre Cifuentes , Ligia Alejandra

    2013-01-01

    Ocular involvement, mainly retinochoroiditis, is one of the most severe sequelae of Toxoplasma gondii infection. However, the pathophysiological mechanisms of retinal destruction are poorly understood. Several studies suggested a more frequent and more severe ocular involvement in South American infections compared with European infections, probably due to different T. gondii strains (Type I/III, and atypical vs. Type II). To compare the clinical characteristics and biological and immunologic...

  19. Otázka slobodnej vôle v helenistickej filozofii (na pozadí Ciceronovho spisu De fato (Die Frage des freien Willens in der hellenistischen Philosophie (In Anbetracht der Ciceros Schrift De fato

    Peter Fraňo

    2010-06-01

    Full Text Available In diesem Beitrag ich beschäftige mich mit der Frage: Ist das menschliche handeln vorbestimmt, oder kann der Einzelne frei entscheiden? Diese problematik wurde in der hellenistischen Philosophie sehr verbreitet. Das erste mal hat diese Frage Aristoteles in seinen Werken: Die Nikomachische Etik und vor allem De Interpretatione erforscht, wo hat sich die logische Problematik des sogenannten περὶ δυνατῶν berührt. Die megarischen Philosophen Diodoros Kronos und Philon von Megara hat auf die Lösung des Aristoteles reagiert. Außer der Logik ist die Problematik des freien Willes der Bestandteil der stoischen Physik (Astrologie, Sympathie uns stoische Ursachen gewesen. In meinem Beitrag ich habe auf diese Gesichtspunkte in Anbetracht der Ciceros Schrift De fato hingewiesen.

  20. Distribuce otěrových částic UHMWPE v periprotetických tkáních u TEP kyčelního kloubu

    Pokorný, D.; Šlouf, Miroslav; Veselý, F.; Fulín, P.; Jahoda, D.; Sosna, A.; Běláček, J.; Landor, I.; Zolotarevova, E.; Popelka, S.

    2010-01-01

    Roč. 77, č. 2 (2010), s. 87-92 ISSN 0001-5415 R&D Projects: GA MŠk 2B06096 Institutional research plan: CEZ:AV0Z40500505 Keywords : total hip replacement * polyethylene wear * aseptic loosening Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.628, year: 2009 http://www.achot.cz/detail.php?stat=346

  1. Dva dokumenty k otázce prodloužení dvouleté lhůty dodatkového protokolu československo-polské smlouvy z roku 1947

    Friedl, Jiří

    2009-01-01

    Roč. 95, č. 4 (2009), s. 483-489 ISSN 0037-6922 R&D Projects: GA ČR GA409/09/0951 Institutional research plan: CEZ:AV0Z80150510 Keywords : Czechoslovakia * Poland * relations * treaty of alliance Subject RIV: AB - History

  2. Results of investigations of an 0.010-scale 140A/B configuration (model 72-OTS) of the Rockwell International space shuttle orbiter in the NASA/Langley Research Center unitary plan wind tunnel

    Petrozzi, M. T.; Milam, M. D.

    1975-01-01

    Experimental aerodynamic investigations were conducted in the NASA/Langley unitary plan wind tunnel on a sting mounted 0.010-scale outer mold line model of the 140A/B configuration of the Rockwell International Space Shuttle Vehicle. The primary test objectives were to obtain: (1) six component force and moment data for the mated vehicle at subsonic and transonic conditions, (2) effects of configuration build-up, (3) effects of protuberances, ET/orbiter fairings and attach structures, and (4) elevon deflection effects on wing bending moment. Six component aerodynamic force and moment data and base and balance cavity pressures were recorded over Mach numbers of 1.6, 2.0, 2.5, 2.86, 3.9, and 4.63 at a nominal Reynolds number of 20 to the 6th power per foot. Selected configurations were tested at angles of attack and sideslip from -10 deg to +10 deg. For all configurations involving the orbiter, wing bending, and torsion coefficients were measured on the right wing.

  3. Otázka předlokačního a lokačního Brna v konfrontaci písemných a archeologických pramenů

    Procházka, Rudolf

    2009-01-01

    Roč. 12, - (2009), s. 103-112. ISBN 978-80-89175-34-5. ISSN N R&D Projects: GA ČR GA404/09/1966 Institutional research plan: CEZ:AV0Z80010507 Keywords : Moravia * Town Brno * Late Middle age * foundations of the Town Subject RIV: AC - Archeology, Anthropology, Ethnology

  4. Šlechtické kapely v českých zemích doby baroka: staré a nové otázky jejich zkoumání

    Kapsa, Václav

    2014-01-01

    Roč. 3, č. 1 (2014), s. 177-182 ISSN 1803-7747 Institutional support: RVO:68378076 Keywords : history of music * Bohemian lands * music ensembles * Kapellen * aristocracy Subject RIV: AL - Art, Architecture, Cultural Heritage http://www.acecs.cz/ media /cu_2014_03.pdf

  5. Ajakirjandusliku väljendusvabaduse erisused : ajakirjandusvabaduse aspekt sõnavabaduse piiramisel, arvestades Euroopa Inimõiguste Kohtu praktikat : [bakalaureusetöö] / Kristjan Ots ; Tartu Ülikool, õigusteaduskond ; juhendaja: Kalle Merusk

    Ots, Kristjan, 1976-

    2001-01-01

    Sõnavabaduse mõiste, koht konstitutsioonis, sõnavabaduse piiramise piirid, tsensuur, ajakirjandusvabaduse eristamine sõnavabadusest, ajakirjandusliku väljendusvabaduse põhimõtted, ajakirjanduse funktsioonid, sõnavabaduse aspekt, teabevabaduse aspekt, teotamine e. difamatsioon, ajakirjandusvabaduse piiramine õigusemõistmise huvides

  6. Sociálně pedagogické otázky integrace romských dětí a mládeže

    Čadová, Markéta

    2010-01-01

    This work is of a theoretical-empirical nature. The goal of this work is to identify causes with lead to the social exclusion of the Romany ethnic group, to chart trends in this region, and to focus attention on institutions engaged in integrating Roma into society. Additional goals are to determine how the integration of this minority is secured by the government, through self-government and non-profit organizations, and subsequently to attempt to determine how the Roma people and the majori...

  7. Identificación de escenarios de calidad de hábitat para fauna silvestre : caso de estudio| cuenca media y alta del río Otún (Risaralda)

    García Gómez, Martha Patricia

    2009-01-01

    Este trabajo contiene eje clave de investigación las dinámicas espaciales de cambio en la calidad del hábitat para fauna silvestre, a partir de la transformación de coberturas dentro de las áreas protegidas (sistemas naturales) y los sistemas reproductivos. Se presenta la estructura de un modelo basado en la utilización de software SIG. Lógica difusa y Agentes Inteligentes a partir del cual se logra la simulación de escenarios de calidad de hábitat para la especie ?zorros? en la cuenca media ...

  8. Svědectví písemných pramenů k otázce vyměřování velkých návsí na Rakovnicku

    Dohnal, Martin

    2013-01-01

    Roč. 39, č. 2 (2013), s. 213-235 ISSN 0323-0988 R&D Projects: GA ČR(CZ) GAP410/11/1287 Keywords : urbanism * medieval settlement * Early Modern settlement * 1200-1900 * Bratronice (district of Rakovník) Subject RIV: AC - Archeology, Anthropology, Ethnology

  9. Estructura funcional y composición de la comunidad de pequeños mamíferos terrestres en el bosque andino del santuario de flora y fauna Otún Quimbaya, Risaralda

    Swanni Alvarado R.

    2005-07-01

    que el BNM tiene los valores más altos de diversidad y la mayor riqueza, mientras que la menor diversidad y riqueza fue encontrada en el BR. El BNM y el BR son más similares según el índice de Morisita y un análisis de Cluster. Para ordenar las especies por las variables morfológicas externas se realizó un Análisis de Componentes Principales, el cual mostró una agrupación de especies pequeñas y otra de especies intermedias, que podría estar indicando que no hay una competencia marcada por un mismo recurso.

  10. Results of wind tunnel tests of an ASRM configured 0.03 scale Space Shuttle integrated vehicle model (47-OTS) in the AEDC 16-foot Transonic wind tunnel (IA613A), volume 1

    Marroquin, J.; Lemoine, P.

    1992-01-01

    An experimental Aerodynamic and Aero-Acoustic loads data base was obtained at transonic Mach numbers for the Space Shuttle Launch Vehicle configured with the ASRM Solid Rocket Boosters as an increment to the current flight configuration (RSRB). These data were obtained during transonic wind tunnel tests (IA 613A) conducted in the Arnold Engineering Development Center 16-Foot transonic propulsion wind tunnel from March 27, 1991 through April 12, 1991. This test is the first of a series of two tests covering the Mach range from 0.6 to 3.5. Steady state surface static and fluctuating pressure distributions over the Orbiter, External Tank and Solid Rocket Boosters of the Shuttle Integrated Vehicle were measured. Total Orbiter forces, Wing forces and Elevon hinge moments were directly measured as well from force balances. Two configurations of Solid Rocket Boosters were tested, the Redesigned Solid Rocket Booster (RSRB) and the Advanced Solid Rocket Motor (ASRM). The effects of the position (i.e. top, bottom, top and bottom) of the Integrated Electronics Assembly (IEA) box, mounted on the SRB attach ring, were obtained on the ASRM configured model. These data were obtained with and without Solid Plume Simulators which, when used, matched as close as possible the flight derived pressures on the Orbiter and External Tank base. Data were obtained at Mach numbers ranging from 0.6 to 1.55 at a Unit Reynolds Number of 2.5 million per foot through model angles of attack from -8 to +4 degrees at sideslip angles of 0, +4 and -4 degrees.

  11. Base pressure and heat transfer tests of the 0.0225-scale space shuttle plume simulation model (19-OTS) in yawed flight conditions in the NASA-Lewis 10x10-foot supersonic wind tunnel (test IH83)

    Foust, J. W.

    1979-01-01

    Wind tunnel tests were performed to determine pressures, heat transfer rates, and gas recovery temperatures in the base region of a rocket firing model of the space shuttle integrated vehicle during simulated yawed flight conditions. First and second stage flight of the space shuttle were simulated by firing the main engines in conjunction with the SRB rocket motors or only the SSME's into the continuous tunnel airstream. For the correct rocket plume environment, the simulated altitude pressures were halved to maintain the rocket chamber/altitude pressure ratio. Tunnel freestream Mach numbers from 2.2 to 3.5 were simulated over an altitude range of 60 to 130 thousand feet with varying angle of attack, yaw angle, nozzle gimbal angle and SRB chamber pressure. Gas recovery temperature data derived from nine gas temperature probe runs are presented. The model configuration, instrumentation, test procedures, and data reduction are described.

  12. Results of investigations conducted in the LaRC 8-foot transonic pressure tunnel using the 0.010-scale 72-OTS model of the space shuttle integrated vehicle (IA93), volume 2

    Nichols, M. E.

    1976-01-01

    Test procedures, history, and plotted coefficient data are presented for an aero-loads investigation on the updated configuration-5 space shuttle launch vehicle at Mach numbers from 0.600 to 1.205. Six-component vehicle forces and moments, base and sting-cavity pressures, elevon hinge moments, wing-root bending and torsion moments, and normal shear force data were obtained. Full simulation of updated vehicle protuberances and attach hardware was employed.

  13. Results of wind tunnel tests of an ASRM configured 0.03 scale Space Shuttle integrated vehicle model (47-OTS) in the AEDC 16-foot transonic wind tunnel, volume 2

    Marroquin, J.; Lemoine, P.

    1992-01-01

    An experimental Aerodynamic and Aero-Acoustic loads data base was obtained at transonic Mach numbers for the Space Shuttle Launch Vehicle configured with the ASRM Solid Rocket Boosters as an increment to the current flight configuration (RSRB). These data were obtained during transonic wind tunnel tests (IA 613A) conducted in the Arnold Engineering Development Center 16-Foot transonic propulsion wind tunnel from March 27, 1991 through April 12, 1991. This test is the first of a series of two tests covering the Mach range from 0.6 to 3.5. Steady state surface static and fluctuating pressure distributions over the Orbiter, External Tank and Solid Rocket Boosters of the Shuttle Integrated Vehicle were measured. Total Orbiter forces, Wing forces and Elevon hinge moments were directly measured as well from force balances. Two configurations of Solid Rocket Boosters were tested, the Redesigned Solid Rocket Booster (RSRB) and the Advanced Solid Rocket Motor (ASRM). The effects of the position (i.e., top, bottom, top and bottom) of the Integrated Electronics Assembly (IEA) box, mounted on the SRB attach ring, were obtained on the ASRM configured model. These data were obtained with and without Solid Plume Simulators which, when used, matched as close as possible the flight derived pressures on the Orbiter and External Tank base. Data were obtained at Mach numbers ranging from 0.6 to 1.55 at a Unit Reynolds Number of 2.5 million per foot through model angles of attack from -8 to +4 degrees at sideslip angles of 0, +4 and -4 degrees.

  14. Results of investigations conducted in the LaRC 8-foot transonic pressure tunnel using the 0.010-scale 72-OTS model of the space shuttle integrated vehicle (IA93)

    Nichols, M. E.

    1976-01-01

    Test procedures, history, and data from the wind tunnel test are presented. Aero-loads were investigated on the updated configuration-5 space shuttle launch vehicle at Mach numbers from 0.600 to 1.205. Six-component vehicle forces and moments, base and sting-cavity pressures, elevon hinge moments, wing-root bending and torsion moments, and normal shear force data were obtained. Full simulation of updated vehicle protuberances and attach hardware was employed. Various elevon deflection angles were tested with two different forward orbiter-to-external-tank attach-strut configurations. The entire model was supported by means of a balance mounted in the orbiter through its base and suspended from a sting.

  15. K otázce lidských práv tzv. druhé generace a jejich reflex do ústavního práva na lidskou důstojnost

    Güttler, Vojen

    2014-01-01

    Roč. 153, č. 6 (2014), s. 501-511 ISSN 0231-6625 Institutional support: RVO:68378122 Keywords : human rights * social rights * Charter of Fundamental Rights and Freedoms Subject RIV: AG - Legal Sciences

  16. Slovarnõi zapass; Utrennjaja muzõka; Mõsl; Absoljutnõi jumor : tshitaja Jannisa Ritsosa; Ne prihhodi; Ne pomnju; Svet vdohnovenja; 'Kogda ot imeni tehh...'; 'Kto szhalitsja kto pozhalejet tehh...'; 'Na povorote skrezheshtshet tramvai...'; Prosto

    Traat, Mats, 1936-

    1996-01-01

    Orig.: Sõnavara; Hommikumuusika; Mõte; Absoluutne huumor : Jannis Ritsost lugedes; Ära tule; Ei mäleta; "Kui nende nimel..."; "Kes heidab armu neile..."; "Pöörakul krigiseb tramm..."; Lihtsa naise elu

  17. Bydlení, bytová otázka a bytové poměry v Baťově Zlíně v letech 1918- 1938

    Ševeček, Ondřej

    2006-01-01

    Roč. 104, č. 1 (2006), s. 18-48 ISSN 0037-6833 Institutional research plan: CEZ:AV0Z90090514 Keywords : Urbanization * industrial housing * company town Zlin * Bata company Subject RIV: AA - Philosophy ; Religion

  18. Nové poznatky a otázky nad hrádkem Rohy u Skřinářova, okr. Zďár n. S.

    Unger, J.; Velek, J.; Kirchner, Karel; Zduba, J.

    2017-01-01

    Roč. 69, č. 3 (2017), s. 252-258 ISSN 0323-2581 Institutional support: RVO:68145535 Keywords : Moravia * middle ages * castle * colonization * mining Subject RIV: AC - Archeology, Anthropology, Ethnology OBOR OECD: Antropology, ethnology

  19. Kiril Christov - pevec neudovletvoren, no neizpadašt v otčajanie... Kăm văprosa za rannata recepcija na tvorčestvoto mu v Čechija (do 1918 g.)

    Černý, Marcel

    2017-01-01

    Roč. 5, č. 10 (2017) ISSN 1314-9067 Institutional support: RVO:68378017 Keywords : Khristov, Kiril * Prague * artistic translation * literary reception * Czech-Bulgarian cultural relations * Bulgarian opera * literary adaptation of folklore * eroticism * Šak, Vladislav * Tichý, František Rut Tichý = Broman, Zdeněk * Macháň, Karel * Páta, Josef Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures http://www.abcdar.com/magazine/X/%C4%8Cern%C3%BD_1314-9067_X.pdf

  20. Česká počítačově generovaná literatura a otázka autorství literárního textu

    Piorecký, Karel

    2017-01-01

    Roč. 9, č. 3 (2017), s. 66-78 ISSN 1337-9275 R&D Projects: GA MŠk(CZ) EF16_013/0001743 Institutional support: RVO:68378068 Keywords : generative literature * glitch art * google poetry * artificial intelligence * authorship * network theory of actors Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures

  1. Experimental study of isospin mixing in 12C + n → 13C(T = 3/2) and 16O + n → 17O(T = 3/2) resonances

    Cierjacks, S.; Schmalz, G.; Hinterberger, F.; Rossen, P. v.

    1981-12-01

    Narrow resonances of 13 C and 17 O have been studied by a measurement of the total neutron cross sections of carbon and oxygen between 3 and 30 MeV. Employing the improved time-of-flight spectrometer at the Karlsruhe Isochronous Cyclotron and precise calibration methods, resonance cross sections were measured with an energy resolution of 1:2100 at 10 MeV and energy accuracies between 10 -4 and 10 -5 . Resonance analysis of the measured data provided parameters for numerous narrow states of both isospins, T = 1/2 and T = 3/2. These data in conjunction with information from broad T = 1/2 resonances provided a good means to experimentally determine isospin mixing matrix elements. Results were obtained for the first five T = 3/2 resonances in 17 O and the first T = 3/2 resonance in 13 C. The obtained mixing matrix elements are compared with previous experimental results and shell-modell predictions of this quantity. (orig.) [de

  2. Non-orthogonally transitive G2 spike solution

    Lim, Woei Chet

    2015-01-01

    We generalize the orthogonally transitive (OT) G 2 spike solution to the non-OT G 2 case. This is achieved by applying Geroch’s transformation on a Kasner seed. The new solution contains two more parameters than the OT G 2 spike solution. Unlike the OT G 2 spike solution, the new solution always resolves its spike. (fast track communication)

  3. Stability of infinite ranges and kernels

    Förster, K.-H.; Müller, Vladimír

    2006-01-01

    Roč. 174, č. 1 (2006), s. 61-73 ISSN 0039-3223 R&D Projects: GA ČR(CZ) GA201/06/0128 Institutional research plan: CEZ:AV0Z10190503 Keywords : Kato operators * essentially Kato operators * regular operator-valued functions Subject RIV: BA - General Mathematics Impact factor: 0.515, year: 2006

  4. Pixel super resolution using wavelength scanning

    2016-04-08

    13 Celebi ME, Schaefer G. Color Medical Image Analysis. Netherlands: Springer. 2013. 14 Yamaguchi I, Matsumura T, Kato J. Phase-shifting color...2016.60 15 Kato J, Yamaguchi I, Matsumura T. Multicolor digital holography with an achromatic phase shifter. Opt Lett 2002; 27: 1403–1405. 16 Ferraro P

  5. A Low-Level Geiger-Counter for Tritium; Compteur Geiger a faible mouvement propre pour le tritium; Schetchik Gejgera s nizkim urovnem dlya tritiya; Contador Geiger de baja actividad de fondo para tritio

    Von Buttlar, H; Stahl, W [Technische Hochschule, Darmstadt (Germany)

    1962-01-15

    pour controler la stabilite a long terme du systeme. (author) [Spanish] Contador Geiger de baja actividad de fondo para tritio. Los autores construyeron un tubo contador cilindrico de 11 l que contiene una serie de conductores de anticoincidencia en torno a un contador central de 2,9 l de volumen efectivo. La seccion de anticoincidencia esta separada del contador central por una delgada hoja de Hostaphan aluminizada. En el trabajo figura una serie de detalles constructivos. El gas que llena el contador consiste en una mezcla de etileno a 30 mm, de argon a 40 mm y la muestra de hidrogeno hasta 700 mm. Un circuito de extincion externo, cuyo tiempo muerto es de 7 ms, elimina eficazmente todos los impulsos demorados. Con un blindaje de hierro de 30 cm, el indice de recuento del contador central con hidrogeno gaseoso inerte es de 350 impulsos/min cuando el circuito de anticoincidencia no funciona y de unos 3 impulsos/min en el caso contrario. Suponiendo que un valor de 1 impulso/min por encima de la actividad de fondo sea significativo, resulta posible medir razones T/H muy pequenas, hasta 10{sup -16}, sin necesidad de proceder a un enriquecimiento isotopico. Se siguen realizando experimentos para verificar la estabilidad a largo plazo del dispositivo. (author) [Russian] Byla skonstruirovan a tsilindricheskaya trubka s ob{sup e}mom v 11 litrov, kotoraya soderzhit ryad provodov antisovpadeniya, okhvatyvayushchikh tsentral'nuyu chast' schetchika emkost'yu v 2,9 litra. TSentral'naya chast' schetchika otdelena ot sektsii antisovpadeniya tonkoj alyuminirovannoj Gostafanovoj fol'goj. Privodyatsya podrobnye dannye konstruktsii. Gaz dlya napolneniya schetchika sostoit iz 30 torr ehtilena, 40 torr argona i do 700 torr obraztsa vodoroda. Vneshnyaya tsep' gasheniya s mertvym vremenem v 7 msek. uspeshno ustranyaet posleduyushchie impul'sy. V 30 cm zheleznom ehkrane skorost' otcheta tsentral'noj chasti schetchika s ''mertvym'' vodorodnym gazom sostavlyaet 350 otschetov v minutu bez

  6. Special Nuclear Material Control by the Power Reactor Operator; Controle des Matieres Nucleaires Speciales par l'Exploitant d'une Centrale Nucleaire; Spetsial'nyj kontrol' nalichiya yadernykh materialov operatorom ehnergeticheskogo reaktora; Control de Materiales Nucleares Especiales por Parte de Quienes Operan el Reactor de Potencia

    Cordin, R. A. [Yankee Atomic Electric Company, Boston, MA (United States)

    1966-02-15

    sushhestvovanija reaktorov nashi inzhenery i uchenye nepreryvno sovershenstvovali konstrukciju ustanovok i uluchshali metody jekspluatacii s cel'ju snizit' sebestoimost' s tem, chtoby nashi jadernye ustanovki mogli byt' konkurentosposoonymi s rabotajushhimi na iskopaemom toplive jelektrostancijami obychnogo tipa. Administrativnohozjajstvennyj uchet jadernyh materialov dolzhen byt' po mere vozmozhnosti sovremennym i jeffektivnym s tem, chtoby tehnologicheskij process, napravlennyj na snizhenie sebestoimosti, ne stradal by iz-za rastochenija jadernogo topliva i nebrezhnogo ego ucheta. Administrativno-hozjajstvennyj uchet trebuet so storony operatora jenergeticheskogo reaktora vedenija polnyh i podrobnyh uchetnyh dokumentov. Dlja udovletvorenija trebovanijam polnoty i nadezhnosti jeti dokumenty vovse ne dolzhny byt' slozhnymi. Naoborot, prostota ih javljaetsja chrezvychajno zhelatel'noj. Nesmotrja na to, chto jadernoe toplivo javljaetsja chem-to novym i sovershenno otlichnym ot topliva obychnogo tipa, nel'zja oblekat' ego pokrovom tainstvennosti. Kontrol' nalichija jadernyh materialov kak chast' administrativno-hozjajstvennogo ucheta jadernyh materialov ne ogranichivaetsja odnoj lish' rabotoj po proverke nalichija materialov, no on lezhit v osnove mnogih drugih vidov dejatel'nosti, javljajushhihsja neot{sup e}mlemoj chast'ju jekspluatacii ljubogo jenergeticheskogo reaktora, kak naprimer, otpravok obluchennogo topliva, pereobrabotki otrabotannogo topliva so svjazannoj s jetim otchetnost'ju pri regeneracii topliva i materiala, proizvedennogo pri rabote reaktora. K jetomu krugu problem otnosjatsja takzhe vyrabotka i osushhestvlenie nadlezhashhej programmy strahovanija. (author)

  7. The isotope-dilution method of fluorine microestimation; Microdosage du fluor pur dilution isotopique; Mikroopredelenie ftora no metodu razbavleniya izotopov; Microvaloracion del fluor por dilucion isotopica

    Kudahl, J N; Fremlin, J H; Hardwick, J L [Department of Physics, University of Birmingham (United Kingdom)

    1962-01-15

    pomeshchayutsya na opredelennuyu ploshchad' stekla, to nekotoroe kolichestvo F{sup 18} adsorbiruetsya i po ustanovlenii sostoyaniya ravnovesiya mozhet byt' zakrepleno posredstvom uvelicheniya pH. Radioaktivnost' stekla mozhet sluzhit' meroj obshchego kolichestva ftora na stekle i ehta mera mozhet byt' ispol'zovana dlya postroeniya izotermy adsorbtsii, iz kotoroj mozhno vyvesti soderzhanie ftora v neizvestnom rastvore dannoj serii. Bylo izucheno vliyanie pokazatelya rN i prisutstvie ionov kal'tsiya i fosfata i pokazano, chto organicheskie materialy mozhno szhigat' bez kakoj-libo opasnosti, esli oni soderzhat iony kal'tsiya i magniya. Tochnost' ehtogo metoda ne zavisit ot kontsentratsii ftora v rastvorakh, krepost' kotorykh mozhet vyrazhat'sya menee, chem v odnu chast' na million. (author)

  8. Urinary and plasma oxytocin changes in response to MDMA or intranasal oxytocin administration.

    Francis, Sunday M; Kirkpatrick, Matthew G; de Wit, Harriet; Jacob, Suma

    2016-12-01

    The neuropeptide oxytocin (OT) has received increased experimental attention for its putative role in both normal social functioning and several psychiatric disorders that are partially characterized by social dysfunction (e.g., autism spectrum disorders: ASD). Many human experimental studies measure circulating plasma levels of OT in order to examine the relationship between the hormone and behavior. Urinary OT (uOT) assays offer a simple, easy, and non-invasive method to measure peripheral hormone levels, but the correspondence between uOT and plasma OT (pOT) levels is unclear. Here, we conducted two within-subjects, double-blind studies exploring changes in uOT and pOT levels following administration of two drugs: MDMA, an oxytocin-releasing drug (Study 1), and intranasal oxytocin (INOT: Study 1 and 2). In Study 1, 14 adult participants (2 females) were each administered either oral 1.5mg/kg MDMA or 40IU INOT across two different study sessions. In Study 2, 10 male participants (adolescents and young adults) diagnosed with ASD received either 40IU INOT or placebo across two different sessions. In both studies, blood and urine samples were collected before and after drug administration at each study session. For Study 1, 10 participants provided valid plasma and urine samples for the MDMA session, and 8 provided valid samples for the INOT session. For Study 2, all 10 participants provided valid samples for both INOT and placebo sessions. Pre- and post-administration levels of pOT and uOT were compared. Additionally, correlations between percent change from baseline uOT and pOT levels were examined. Study 1: Plasma OT and uOT levels significantly increased after administration of MDMA and INOT. Furthermore, uOT levels were positively correlated with pOT levels following administration of MDMA (r=0.57, p=0.042) but not INOT (r=0.51, p=0.097). Study 2: There was a significant increase in uOT levels after administration of INOT, but not after administration of

  9. Effect of oxytocin injection to milching buffaloes on its content & stability in milk

    Raghu Pullakhandam

    2014-01-01

    Full Text Available Background & objectives: Oxytocin (OT injections to milch cattle for milk letdown have become a common practice amongst dairy farmers in India. Although there is no reported evidence, it is widely presumed that long term consumption of such milk leads to adverse health consequences. However, there is no information on the effect of exogenous OT injections on milk OT content and its stability during heating and gastrointestinal digestion. This study was carried out to determine the OT content in milk samples given by buffaloes with and without OT injections and to assess the stability of OT in the milk. Methods: Milk samples from milch buffaloes (Murrah buffalo were collected from local farmers with (n=121 or without (n=120 exogenous OT injections during 3 to 5 months of lactation period. The OT content of milk samples was estimated by competitive enzyme immunoassay (EIA. The thermal and digestive stability of OT was assessed by in silico and in vitro digestion methods. Results: The OT content of the milk samples was similar regardless of OT injections used. Further, OT was found to be stable to heat treatment and gastric pepsin digestion while it was rapidly digested during the simulated intestinal digestion. r0 educed OT was digested by pepsin, implying that internal disulphide bridge of OT rendered the peptide resistant to peptic digestion. On the other hand, phenylmethylsulphonyl fluoride (PMSF, a serine protease inhibitor, abrogated the pancreatin induced digestion of OT. Interpretation & conclusions: These findings suggest that exogenous OT injections do not influence its content in milk. Further, OT present in milk is rapidly degraded during intestinal digestion, ruling out its intestinal absorption and associated adverse health consequences, if any.

  10. The Natural and Cultural Environmental Resources of the Aquilla Creek Watershed, Hill County, Texas.

    1972-11-01

    Vernonia baldwinii Torr. Western Ironweed Viburnum rufidulum Raf. Black Haw Vicia dasycarpa Ten. Winter (Wooly-pod) Vetch Vitex agnus -castus L. Chaste-tree... DISTRIBUTION STATEMENT (of this Report) Approved for public release; distribution unlimited 17. DISTRIBUTION STATEMENT (of the abstract entered In...Bacteria. 207 Table 45. Macrobenthos. 208 Table 46. Turbidity. 209 Table 47. Relative Transparency. 209 Table 48. Distribution of invertebrates in

  11. The effect of vitex agnus-castus on mastalgia in women

    Leili Sekhavat; Tahereh Zare Tarzejani; Parvin Kholase zadeh

    2009-01-01

    Background: Vitex agnus-castus is a herbal drug with antiprolactin effect and it is effective in premenstrual syndrome and hypermenorrhea. The purpose of this study was to evaluate vitex agnus-castus extract (chaste tree) in comparison with placebo in treating patients with mastalgia, and evaluation of its acceptability and side effects. Methods: In a double-blind, randomized clinical trial, 117 women with mastalgia, aged 15-50 years old, referring to women’s health centers, were divided into...

  12. 75 FR 35686 - Community Reinvestment Act Regulation Hearings

    2010-06-23

    ... will post comments on the OTS Internet Site at http://www.ots.treas.gov/?p=LawsRegulations . Viewing... consider violations of additional consumer laws, such as the Truth in Savings Act, the Electronic Fund...

  13. Body composition, metabolism, sleep, psychological and eating patterns of overtraining syndrome: Results of the EROS study (EROS-PROFILE).

    Cadegiani, Flavio A; Kater, Claudio E

    2018-08-01

    Overtraining syndrome (OTS) is caused by an imbalance between training, nutrition and resting, and leads to decreased performance and fatigue; however, the precise underlying triggers of OTS remain unclear. This study investigated the body composition, metabolism, eating, sleeping patterns and mood states among participants with OTS. Selected participants were divided into OTS-affected athletes (OTS, n = 14), healthy athletes (ATL, n = 25), and healthy non-physically active controls (NCS, n = 12). Compared to ATL, OTS showed decreased sleep quality (p = 0.004); increased duration of work or study (p sleep, and increased cognitive activity are likely OTS triggers. OTS appears to induce dehydration, increase body fat, decrease libido, and worsen mood.

  14. Spinal Cord Injury 101

    Full Text Available ... L Sarah Harrison, OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury ... a spinal cord injury important? play_arrow What role does “compression” play in a spinal cord injury? ...

  15. Preventing Pressure Sores

    Full Text Available ... L Sarah Harrison, OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury ... do to prevent pressure sores? play_arrow What role does diet and hydration play in preventing pressure ...

  16. Spinal Cord Injury 101

    Full Text Available ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW Marguerite ... play_arrow What are the latest developments in the use of electrical stimulation for spinal ...

  17. Awareness and Use of Electronic Health Records in Entry-Level Occupational Therapy and Occupational Therapy Assistant Curricula

    Louis F. Dmytryk

    2017-03-01

    Full Text Available The Accreditation Council for Occupational Therapy Education (ACOTE requires programs to instruct entrylevel occupational therapy (OT and occupational therapy assistant (OTA students in technology that may include electronic documentation systems, distance communication, virtual environments, and telehealth (standard B1.8. At this time, there are no publications describing if and how electronic health record (EHR instruction is implemented in entry-level OT and OTA programs. The purpose of this study is to investigate awareness and use of EHRs in entry-level OT and OTA curricula. Respondents from 76 nationally accredited entry-level programs (two OT doctoral, 24 OT masters, two OT combined bachelors/masters, and 48 OTA completed a survey. The findings showed inconsistent and incomplete EHR instruction in entry-level OT and OTA education. This study provides a baseline for investigating best practices in EHR education for entrylevel OT and OTA students

  18. Basics of SCI Rehabilitation

    Full Text Available ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ... Experiences By Topic Resources Blog Peer Counseling About Media Donate Contact Us Terms of Use Site Map ...

  19. Sex and Fertility After SCI

    Full Text Available ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ... Experiences By Topic Resources Blog Peer Counseling About Media Donate Contact Us Terms of Use Site Map ...

  20. Spinal Cord Injury 101

    Full Text Available ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ... Experiences By Topic Resources Blog Peer Counseling About Media Donate Contact Us Terms of Use Site Map ...

  1. Preventing Pressure Sores

    Full Text Available ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ... Experiences By Topic Resources Blog Peer Counseling About Media Donate Contact Us Terms of Use Site Map ...

  2. Spinal Cord Injury 101

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  3. Basics of SCI Rehabilitation

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  4. Sex and Fertility After SCI

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  5. Preventing Pressure Sores

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  6. Occupational Therapy intervention for patiens with COPD, Rehabilitation at home

    Larsen, Stina Meyer; Petersen, Anne Karin

    Describe and demonstrate Occupational Therapy (OT) intervention for patients with Chronic Obstructive Pulmonary Disease (COPD).......Describe and demonstrate Occupational Therapy (OT) intervention for patients with Chronic Obstructive Pulmonary Disease (COPD)....

  7. Low dose intranasal oxytocin delivered with Breath Powered device dampens amygdala response to emotional stimuli: A peripheral effect-controlled within- subjects randomized dose-response fMRI trial

    Quintana, Daniel; Westlye, Lars Tjelta; Alnæs, Dag; Rustan, Øyvind; Kaufmann, Tobias; Smerud, Knut Terje; Mahmoud, Ramy; Djupesland, Per G.; Andreassen, Ole Andreas

    2016-01-01

    It is unclear if and how exogenous oxytocin (OT) reaches the brain to improve social behavior and cognition and what is the optimal dose for OT response. To better understand the delivery routes of intranasal OT administration to the brain and the dose-response, we compared amygdala response to facial stimuli by means of functional magnetic resonance imaging (fMRI) in four treatment conditions, including two different doses of intranasal OT using a novel Breath Powered device, intravenous (IV...

  8. Main: PPD203 [AT Atlas

    Full Text Available PPD203 PPD2 LED light for Green Fluorescent Protein (GFP) detection Development of ...innovative methods to support membrane protein crystallization Hiroaki Kato Graduate School of Pharmaceutical Sciences, Kyoto University PPD203.csml ...

  9. Study of Salmonella typhimurium mutagenicity assay of (E ...

    Study of Salmonella typhimurium mutagenicity assay of (E)-piplartine by the Ames test. AA Morandim-Giannetti, F Cotinguiba, LO Regasini, MC Frigieri, EA Varanda, A Coqueiro, MJ Kato, VS Bolzani, M Furlan ...

  10. The role of oxytocin in cardiovascular regulation

    J. Gutkowska

    2014-03-01

    Full Text Available Studies of body volume expansion have indicated that lesions of the anteroventral third ventricle and median eminence block the release of atrial natriuretic peptide (ANP into the circulation. Detailed analysis of the lesions showed that activation of oxytocin (OT-ergic neurons is responsible for ANP release, and it has become clear that activation of neuronal circuitry elicits OT secretion into the circulation, activating atrial OT receptors and ANP release from the heart. Subsequently, we have uncovered the entire functional OT system in the rat and the human heart. An abundance of OT has been observed in the early development of the fetal heart, and the capacity of OT to generate cardiomyocytes (CMs has been demonstrated in various types of stem cells. OT treatment of mesenchymal stem cells stimulates paracrine factors beneficial for cardioprotection. Cardiovascular actions of OT include: i lowering blood pressure, ii negative inotropic and chronotropic effects, iii parasympathetic neuromodulation, iv vasodilatation, v anti-inflammatory activity, vi antioxidant activity, and vii metabolic effects. OT actions are mediated by nitric oxide and ANP. The beneficial actions of OT may include the increase in glucose uptake by CMs and stem cells, reduction in CM hypertrophy, oxidative stress, and mitochondrial protection of several cell types. In experimentally induced myocardial infarction in rats, continuous in vivo OT delivery improves cardiac healing and cardiac work, reduces inflammation, and stimulates angiogenesis. Because OT plays anti-inflammatory and cardioprotective roles and improves vascular and metabolic functions, it demonstrates potential for therapeutic use in various pathologic conditions.

  11. Entry-Level Doctorate for Occupational Therapists: An Assessment of Attitudes of Occupational Therapists and Occupational Therapy Assistants

    McCombie, Randy P.

    2016-01-01

    Purpose: The purpose of this study was to survey occupational therapists (OTs) and occupational therapy assistants (OTAs) on their attitudes toward a possible move to the entry-level doctorate as the mandated singular point of entry into the profession for OTs. Method: The study surveyed a random sample of 600 OTs and 600 OTAs from two…

  12. REGULATION OF THE RAT OXYTOCIN GENE BY ESTRADIOL - EXAMINATION OF PROMOTER ACTIVITY IN TRANSFECTED CELLS AND OF MESSENGER-RIBONUCLEIC-ACID AND PEPTIDE LEVELS IN THE HYPOTHALAMONEUROHYPOPHYSEAL SYSTEM

    BURBACH, JPH; ADAN, RAH; VANTOL, HHM; VERBEECK, MAE; AXELSON, JF; VANLEEUWEN, FW; BEEKMAN, JM; AB, G

    1990-01-01

    Oxytocin (OT) plays a role in reproduction at the level of the pituitary and mammary glands and uterus. This OT is synthesized in the hypothalamo-neurohypophyseal system (HNS). A number of observations have suggested that estrogens regulate the production of OT in the HNS. In this study the effect

  13. Ontogenesis of oxytocin pathways in the mammalian brain: late maturation and psychosocial disorders

    Valery eGrinevich

    2015-01-01

    Full Text Available Oxytocin (OT, the main neuropeptide of sociality, is expressed in neurons exclusively localized in the hypothalamus. During the last decade, a plethora of neuroendocrine, metabolic, autonomic and behavioral effects of OT has been reported. In the urgency to find treatments to syndromes as invalidating as autism, many clinical trials have been launched in which OT is administered to patients, including adolescents and children. However, the impact of OT on the developing brain and in particular on the embryonic and early postnatal maturation of OT neurons, has been only poorly investigated. In the present review we summarize available (although limited literature on general features of ontogenetic transformation of the OT system, including determination, migration and differentiation of OT neurons. Next, we discuss trajectories of OT receptors (OTR in perinatal period. Furthermore, we provide evidence that early alterations, from birth, in the central OT system lead to severe neurodevelopmental diseases such as feeding deficit in infancy and severe defects in social behavior in adulthood, as described in Prader-Willi syndrome. Our review intends to propose a hypothesis about developmental dynamics of central OT pathways, which are essential for survival right after birth and for the acquisition of social skills later on. A better understanding of the embryonic and early postnatal maturation of the OT system may lead to better OT-based treatments in Prader-Willi syndrome and autism.

  14. Anatomy in Occupational Therapy Program Curriculum: Practitioners' Perspectives

    Schofield, Katherine Anne

    2014-01-01

    Anatomy education is undergoing significant transformation. It is unknown whether changes are in accordance with occupational therapy (OT) practice needs. The purpose of this pilot study was to survey OT clinicians to determine their perspectives on the value of anatomy in OT curricula, and anatomical knowledge required for practice. In addition…

  15. 32 CFR 3.4 - Definitions.

    2010-07-01

    ... responsible for approving the OTs acquisition strategy and resulting OT agreement. This official must be at least one level above the Agreements Officer and at no lower level than existing agency thresholds associated with procurement contracts. Awardee. Any business unit that is the direct recipient of an OT...

  16. The Profile of Mood State (POMS) questionnaire as an indicator of ...

    The overtraining syndrome (OTS) is largely a diagnosis of exclusion. The aim of this study was to investigate the compact Profile of Mood State (POMS) questionnaire as an early and accurate indicator for the diagnosis of OTS and the reliability of such findings in a group of athletes diagnosed with OTS, in comparison with a ...

  17. The role of oxytocin in cardiovascular regulation

    Gutkowska, J.; Jankowski, M.; Antunes-Rodrigues, J.

    2014-01-01

    Studies of body volume expansion have indicated that lesions of the anteroventral third ventricle and median eminence block the release of atrial natriuretic peptide (ANP) into the circulation. Detailed analysis of the lesions showed that activation of oxytocin (OT)-ergic neurons is responsible for ANP release, and it has become clear that activation of neuronal circuitry elicits OT secretion into the circulation, activating atrial OT receptors and ANP release from the heart. Subsequently, we have uncovered the entire functional OT system in the rat and the human heart. An abundance of OT has been observed in the early development of the fetal heart, and the capacity of OT to generate cardiomyocytes (CMs) has been demonstrated in various types of stem cells. OT treatment of mesenchymal stem cells stimulates paracrine factors beneficial for cardioprotection. Cardiovascular actions of OT include: i) lowering blood pressure, ii) negative inotropic and chronotropic effects, iii) parasympathetic neuromodulation, iv) vasodilatation, v) anti-inflammatory activity, vi) antioxidant activity, and vii) metabolic effects. OT actions are mediated by nitric oxide and ANP. The beneficial actions of OT may include the increase in glucose uptake by CMs and stem cells, reduction in CM hypertrophy, oxidative stress, and mitochondrial protection of several cell types. In experimentally induced myocardial infarction in rats, continuous in vivo OT delivery improves cardiac healing and cardiac work, reduces inflammation, and stimulates angiogenesis. Because OT plays anti-inflammatory and cardioprotective roles and improves vascular and metabolic functions, it demonstrates potential for therapeutic use in various pathologic conditions

  18. Planets Move in Circles !

    calculus can be done by geometry' and our problem is no exception. The geometrical derivation is quite simple: In a small time interval ot, the magnitude of the velocity changes by ~V= f (GM/r2) ot according to Newton's law. The angle changes by. ~e = (h/r2) ot from the conservation of angular momentum. Dividing the two ...

  19. The role of oxytocin in cardiovascular regulation

    Gutkowska, J.; Jankowski, M. [University of Montreal, CHUM Research Centre, Faculty of Medicine, Department of Medicine, Laboratory of Cardiovascular Biochemistry, Montreal, Quebec, Canada, Laboratory of Cardiovascular Biochemistry, Department of Medicine, Faculty of Medicine, University of Montreal, CHUM Research Centre, Montreal, Quebec (Canada); Antunes-Rodrigues, J. [Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Fisiologia, Ribeirão Preto, SP, Brasil, Departamento de Fisiologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP (Brazil)

    2014-03-03

    Studies of body volume expansion have indicated that lesions of the anteroventral third ventricle and median eminence block the release of atrial natriuretic peptide (ANP) into the circulation. Detailed analysis of the lesions showed that activation of oxytocin (OT)-ergic neurons is responsible for ANP release, and it has become clear that activation of neuronal circuitry elicits OT secretion into the circulation, activating atrial OT receptors and ANP release from the heart. Subsequently, we have uncovered the entire functional OT system in the rat and the human heart. An abundance of OT has been observed in the early development of the fetal heart, and the capacity of OT to generate cardiomyocytes (CMs) has been demonstrated in various types of stem cells. OT treatment of mesenchymal stem cells stimulates paracrine factors beneficial for cardioprotection. Cardiovascular actions of OT include: i) lowering blood pressure, ii) negative inotropic and chronotropic effects, iii) parasympathetic neuromodulation, iv) vasodilatation, v) anti-inflammatory activity, vi) antioxidant activity, and vii) metabolic effects. OT actions are mediated by nitric oxide and ANP. The beneficial actions of OT may include the increase in glucose uptake by CMs and stem cells, reduction in CM hypertrophy, oxidative stress, and mitochondrial protection of several cell types. In experimentally induced myocardial infarction in rats, continuous in vivo OT delivery improves cardiac healing and cardiac work, reduces inflammation, and stimulates angiogenesis. Because OT plays anti-inflammatory and cardioprotective roles and improves vascular and metabolic functions, it demonstrates potential for therapeutic use in various pathologic conditions.

  20. 77 FR 20104 - Privacy Act of 1974, as Amended; System of Records

    2012-04-03

    ... Locator File OTS .012--Payroll/Personnel Systems & Payroll Records OTS .013--Mass Communication System OTS... examination or investigation; (3) The news media in accordance with guidelines contained in 28 CFR 50.2; (4... Information Act Officer, Communications Division, Mailstop 2-3, Office of the Comptroller of the Currency, 250...

  1. Maternal and Paternal Plasma, Salivary, and Urinary Oxytocin and Parent-Infant Synchrony: Considering Stress and Affiliation Components of Human Bonding

    Feldman, Ruth; Gordon, Ilanit; Zagoory-Sharon, Orna

    2011-01-01

    Studies in mammals have implicated the neuropeptide oxytocin (OT) in processes of bond formation and stress modulation, yet the involvement of OT in human bonding throughout life remains poorly understood. We assessed OT in the plasma, saliva, and urine of 112 mothers and fathers interacting with their 4-6-month-old infants. Parent-infant…

  2. Comparison of Oral, Tympanic and Fresh Urine Temperature in ...

    Background: Core body temperature (CBT) is commonly evaluated by measuring oral (OT) and tympanic membrane (TT) temperatures; however, there are considerable debates on which of these methods is the most appropriate. Objective: To evaluate concordance of OT and TT with CBT. Material and Methods: OT, TT and ...

  3. X-ray emission from hot plasma

    Hayakawa, Satio; Kato, Takako.

    1979-01-01

    X-ray emission from hot plasmas is discussed with a critical review of different theories. The results given in the present paper are complementary to those given by Kato in the sense that the present paper is introductory to the paper by Kato. The contents of the present paper are; 1. Introduction 2. Ionization and Recombination Rate Coefficients 3. Relative Abundances of Ions 4. Intensity and Spectra of Radiation 5. Comparison with Earlier Results 6. Emission and Absorption Lines (author)

  4. Schistosomiasis in the Amazon region: is the current diagnostic strategy still appropriate?

    Sousa, Sergei Rodrigo Magalhães de; Carvalho, Alessandra de Queiroz; Cardoso, Joyce Favacho Nogueira; Coelho, Paulo Marcos Zech; Geiger, Stefan Michael; Enk, Martin Johannes

    2017-01-01

    Abstract INTRODUCTION: This study analyzed the performance of the Kato Katz technique in detecting intestinal schistosomiasis in the State of Pará. METHODS: Of three stool samples provided by each of 380 participants, a total of 16 Kato Katz slides were examined to define the reference value (RV) of positives for comparisons. RESULTS: The RV revealed 37 (9.7%) infected participants in contrast to 10 (2.6%) according to a single slide. CONCLUSIONS: This significant underestimation of t...

  5. A general-purpose pulse amplifier; Amplificateur d'impulsions universel; Universal'nyj usilitel' impul'sov; Amplificador de impulsos para uso general

    Hansen, K B [Forsogsanlaeg Riso, Roskilde (Denmark)

    1962-04-15

    usilitelej''. Putem ispol'zovaniya odnogo osnovnogo usilitelya, no s razlichnymi skhemami obratnoj svyazi, primenenie ehtogo metoda daet vozmozhnost' poluchat' predvaritel'nye usiliteli i osnovnye usiliteli s nailuchshimi vozmozhnostyami preobrazovaniya impul'sov i v otnoshenii predstavlyayushchikh naibol'shij interes parametrov, takikh kak, naprimer, kharakteristika linejnosti, ustojchivosti i peregruzki. Tak kak ehtot metod trebuet ispol'zovaniya parallel'noj obratnoj svyazi, to on osobenno khorosho podkhodit dlya predvaritel'nykh usilitelej, tak kak bol'shaya chast' detektorov yavlyaetsya v to zhe samoe vremya generatorami toka. Opisyvaetsya usilitel', dejstvuyushchij v kachestve operatsionnogo usilitelya. Naibolee vazhnymi spetsifikatsiyami yavlyayutsya: usilenie v 90 dB ot postoyannogo toka - 10 kgts, padayushchee zatem priblizitel'no po 20 dB na dekadu do dostizheniya 15 mgts (usilenie v 30 dB). S ehtim usilitelem ispol'zuyutsya chetyre lampy. Dlya bol'shinstva operatsij preobrazovaniya impul'sov potrebnost' v stabilizirovannom istochnike ehlektroehnergii otpadaet, a ustojchivost' budet zaviset' isklyuchitel'no ot ustojchivosti ispol'zovannoj skhemy obratnoj svyazi. (author)

  6. Description of Radiation Sources Installed at the French Atomic Energy Commissariat; Description de sources de rayonnement installees au commissariat a l'energie atomique; Opisanie istochnikov oblucheniya, nakhodyashchikhsya v frantsuzskom komissariate po atomnoj ehnergii; Descripcion de las fuentes de radiaciones instaladas en el commissariat a l'energie

    Leveque, P

    1960-07-15

    organicas, ya que el flujo epitermico y rapido provoca la activacion de la mayor parte de los productos sometidos a la irradiacion. A continuacion, el autor describe las instalaciones del Centro de Aplicaciones Atomicas de Lyon creado en las proximidades de dicha ciudad por un grupo de industriales. Este Centro, que segun esta previsto comenzara a funcionar en 1960, tendra un caracter semi-industrial (para comenzar, una fuente de cobalto-60 de 3 000 curies y mas adelante, otra de 40 000 curies) y permitira realizar operaciones de irradiacion de una manera continua. (author) [Russian] Prezhde vsego avtor daet opisanie chetyrekh ustanovok, nakhodyashchikhsya v yadernom issledovatel'skom tsentre v Sakleh. - Laboratornyj istochnik v 600 kyuri kobal'ta-60; ispol'zuemyj pribor yavlyaetsya prostym i bezopasnym, no ne daet vozmozhnosti izmenyat' potok gamma-luchej. - Pribor, sostoyashchij iz semi istochnikov kobal'ta-60 (samyj moshchnyj v 1000 kyuri), ustanovlennykh v betonnoj kamere; pnevmaticheski j pribor pozvolyaet ustanovit' odin ili neskol'ko neobkhodimykh istochnikov v rabochem polozhenii. - Kamera vmeshchaet 100 sterzhnej yadernogo goryuchego ot novogo reaktora EL3; chast' ehtoj kamery prisposoblena dlya okhlazhdeniya, chto pozvolit proizvodit' opyty nad konservatsiej pishchevykh produktov dejstviem oblucheniya. - Vertikal'nye kanaly reaktora EL 2, tak nazyvaemye ''okna khimika''; kogda ehti kanaly obernuty kadmievoj fol'goj, dostigaemyj potok gamma-luchej perekhodit so 100000 na 200000 rentgeno/chasov, no oni mogut sluzhit' tol'ko dlya oblucheniya organicheskikh materialov, tak kak imeetsya aktivatsiya bol'shej chasti obluchaemykh produktov pri pomoshchi bystrogo ehpitermicheskogo potoka. Zatem avtor daet opisanie pribora, ustanovlennogo v Lionskom tsentre po ispol'zovaniyu atomov, postroennogo okolo Liona gruppoj promyshlennikov. EHtot pribor, pusk v ehkspluatatsiyu kotorogo predusmotren na nachalo 1960 goda, budet nosit' polupromyshlennyj kharakter (istochnik kobal'ta-60

  7. Universal Instability in a Thermal Plasma Device (Q-Machine); Instabilite Universelle dans une Machine a Plasma Thermique (Machine-Q); Issledovaniya universal'noj neustojchivosti v ustrojstve dlya termicheski ionizovannoj plazmy; Inestabilidad Universal en un Dispositivo de Plasma Termico (Maquina Q)

    Lashinsky, H. [University Of Maryland, College Park, MD (United States)

    1966-04-15

    uderzhivajushhemu magnitnomu polju. Sootvetstvujushhie bezrazmernye parametry mogut var'irovat'sja v takih predelah, chtoby rezul'taty mozhno bylo sopostavljat' v celjah sravnenija s plazmami, predstavljajushhimi interes dlja termojadernyh issledovanij, i upravljaemaja neustojchivost' mogla by byt' vyzvana sootvetstvujushhim regulirovaniem anodnogo rezhima na plastinah s metallicheskimi okonchanijami putem ispol'zovanija metodov upravlenija anodom, kotorye rassmatrivajutsja vmeste s osnovnoj'teoriej. Pri ispol'zovanii jetih metodov amplituda ascilljacij, mozhet uderzhivat'sja na proizvol'no ustanovlennyh nizkih urovnjah i povedenie neustojchivosti mozhet byt' proslezheno, nachinaja ot nizkoamplitudnogo (e Empty-Set /kT Tilde-Operator 10{sup -3}) ''kvazi-linejno- go'' rezhima, kotoryj harakterizuetsja monohromaticheskim ''zamknutovidnym'' spektrom, do nelinejnogo rezhima, a zatem do slabo-turbulentnogo sostojanija (e Empty-Set /kT Less-Than-Or-Equivalent-To 1) , kotoroe harakterizuetsja iskazhennym ''haoticheskim'' spektrom. Novyj ''rastrovosproizvodjashhij'' metod daet polnuju kartinu razvitija neustojchivosti i perehoda k turbulentnosti. Jeksperimental'no opredelennye osnovnye harakteristiki neustojchivosti, takie kak chastotnye mody, napravlenie azimutal'nogo rasprostranenija, svojstva kogerentnosti, nezavisimost' plotnosti, zavisimost' magnitnogo polja, prostranstvennaja zavisimost' mo- dovoj amplitudy horosho soglasujutsja v kachestvennom otnoshenii s linejnoj teoriej universal'noj neustojchivosti. Jeksperimenty provodilis' takzhe otnositel'no jeffekta dliny stolba na real'nuju chast' chastoty (popravka primerno v 10%) i na voobrazhaemuju chast'. Jeffekt na voobrazhaemuju chast' imeet mesto blagodarja ionnomu dempfirovaniju Landau, i dannyj metod javljaetsja otlichnym sredstvom izuchenija samogo mehanizma dempfirovanija Landau. Rezul'taty jetih jeksperimentov takzhe horosho soglasujutsja s linejnoj teoriej i, krome togo, obnaruzhivajut rjad nelinejnyh jeffektov, takih kak

  8. Manufacture of Wood-Plastic Combinations by Use of Gamma Radiation; Fabrication de combinaisons bois-matiere plastique a l'aide des rayons gamma; Proizvodstvo drevesno-plastmassovykh sostavov s pomoshch'yu gamma-izlucheniya; Impregnacion de maderas con materiales plasticos en presencia de radiaciones gamma

    Kent, J. A.; Winston, A.; Boyle, W.; Updyke, L. [Engineering Experiment Station, West Virginia University, Morgantown, West Virginia (United States)

    1963-11-15

    maderas de pino albar, encina blanca, encina roja, alamo, abedul, haya, abeto y arce sacarino. Se indica el efecto de la intensidad de dosis sobre las velocidades de polimerizacion en esas combinaciones, algunas de las cuales son incompatibles. Por ejemplo, la secoya no permite la polimerizacion del acetato de vinilo o del metacrilato de metilo, en tanto que el pino albar imposibilita la polimerizacion del acetato de vinilo. Los autores estudiaron diversos agentes de reticulacion con miras a determinar su eficacia para acelerar la polimerizacion y, con ello, conseguir ciclos mas breves, y exponen los resultados obtenidos para el acrilato de alilo, el dimetacrilato de etilenglicol, el dimetacrilato de polietilenglicol, el titanato de tetra-isopropilo, el metacrilato de alilo y (en el caso del estireno) el divinilbenceno. Los ensayos mecanicos realizados con maderas impregnadas ponen de manifiesto una mejora de propiedades tales como la dureza, el limite de elasticidad en la compresion y la estabilidad dimensional. Por lo general, se registra un aurpento de la fragilidad respecto de la madera natural. En la memoria se incluyen datos sobre la dureza, el limite de elasticidad en la compresion, la estabilidad en la compresion, la estabilidad dimensional, asi como la resistencia a la flexion y al cizallamiento. (author) [Russian] Opisan promyshlennyj metod polucheniya drevesno-plastmassovykh ''splavov'' s pomoshch'yu gamma-izlucheniya. Protsess sostoit iz dvukh chastej: propitki otobrannoj drevesiny neobkhodimym monomerom i polimerizatsii monomera v meste nakhozhdeniya .s pomoshch'yu gamma-luchej. Izucheno vliyanie razlichnykh faktorov na proniknovenie monomera v drevesinu. Provedennye ispytaniya pokazali, chto na praktike osushchestvimo khoroshee raspredelenie polimera v konechnom produkte. Odnu chast' obraztsov tolshchinoj 10 cm i dlinoj 150 cm podvergli propitke i issledovali na pronikanie monomera, v to vremya kak druguyu chast' obraztsov takoj zhe tolshchiny uspeshno

  9. Oxytocin in the prelimbic medial prefrontal cortex reduces anxiety-like behavior in female and male rats.

    Sabihi, Sara; Durosko, Nicole E; Dong, Shirley M; Leuner, Benedetta

    2014-07-01

    The neuropeptide oxytocin (OT) is anxiolytic in rodents and humans. However, the specific brain regions where OT acts to regulate anxiety requires further investigation. The medial prefrontal cortex (mPFC) has been shown to play a role in the modulation of anxiety-related behavior. In addition, the mPFC contains OT-sensitive neurons, expresses OT receptors, and receives long range axonal projections from OT-producing neurons in the hypothalamus, suggesting that the mPFC may be a target where OT acts to diminish anxiety. To investigate this possibility, female rats were administered OT bilaterally into the prelimbic (PL) region of the mPFC and anxiety-like behavior assessed. In addition, to determine if the effects of OT on anxiety-like behavior are sex dependent and to evaluate the specificity of OT, male and female anxiety-like behavior was tested following delivery of either OT or the closely related neuropeptide arginine vasopressin (AVP) into the PL mPFC. Finally, the importance of endogenous OT in the regulation of anxiety-like behavior was examined in male and female rats that received PL infusions of an OT receptor antagonist (OTR-A). Overall, even though males and females showed some differences in their baseline levels of anxiety-like behavior, OT in the PL region of the mPFC decreased anxiety regardless of sex. In contrast, neither AVP nor an OTR-A affected anxiety-like behavior in males or females. Together, these findings suggest that although endogenous OT in the PL region of the mPFC does not influence anxiety, the PL mPFC is a site where exogenous OT may act to attenuate anxiety-related behavior independent of sex. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Sex-Specific Effects of Stress on Oxytocin Neurons Correspond With Responses to Intranasal Oxytocin.

    Steinman, Michael Q; Duque-Wilckens, Natalia; Greenberg, Gian D; Hao, Rebecca; Campi, Katharine L; Laredo, Sarah A; Laman-Maharg, Abigail; Manning, Claire E; Doig, Ian E; Lopez, Eduardo M; Walch, Keenan; Bales, Karen L; Trainor, Brian C

    2016-09-01

    Oxytocin (OT) is considered to be a stress-buffering hormone, dampening the physiologic effects of stress. However, OT can also be anxiogenic. We examined acute and long-lasting effects of social defeat on OT neurons in male and female California mice. We used immunohistochemistry for OT and c-fos cells to examine OT neuron activity immediately after defeat (n = 6-9) and 2 weeks (n = 6-9) and 10 weeks (n = 4-5) later. We quantified Oxt messenger RNA with quantitative polymerase chain reaction (n = 5-9). Intranasal OT was administered to naïve and stressed mice tested in social interaction and resident-intruder tests (n = 8-14). Acute exposure to a third episode of defeat increased OT/c-fos colocalizations in the paraventricular nucleus of both sexes. In the medioventral bed nucleus of the stria terminalis, defeat increased Oxt messenger RNA, total OT neurons, and OT/c-fos colocalizations in female mice but not male mice. Intranasal OT failed to reverse stress-induced social withdrawal in female mice and reduced social interaction behavior in female mice naïve to defeat. In contrast, intranasal OT increased social interaction in stressed male mice and reduced freezing in the resident-intruder test. Social defeat induces long-lasting increases in OT production and OT/c-fos cells in the medioventral bed nucleus of the stria terminalis of female mice but not male mice. Intranasal OT largely reversed the effects of stress on behavior in male mice, but effects were mixed in female mice. These results suggest that changes in OT-sensitive networks contribute to sex differences in behavioral responses to stress. Copyright © 2015 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  11. Cigarette smoke inhalation increases the alveolar bone loss caused by primary occlusal trauma in a rat model.

    Campos, M L G; Corrêa, M G; Júnior, F H N; Casati, M Z; Sallum, E A; Sallum, A W

    2014-04-01

    Occlusal trauma (OT) and smoking are both factors that alter alveolar bone metabolism and therefore could synergistically act on alveolar bone loss. The aim of this experimental study was to evaluate the influence of short-term cigarette smoke inhalation (CSI) on inter-radicular alveolar bone loss promoted by primary OT in a rat model. Forty-eight animals were randomly assigned to one of three groups based on treatment type: OT + CSI (n = 16), animals were exposed to CSI three times per day, for 8 min per exposure, and they concomitantly received unilateral vertical augmentation creating an occlusal interference inducing experimental OT; OT (n = 16), animals received only unilateral vertical augmentation; negative control (NC; n = 16), animals maintained for equal periods to achieve periodontal baseline values of periodontal ligament dimension. Each group was divided into two subgroups (n = 8) based on treatment length: 7 or 14 d. After 7 d, the OT + CSI group exhibited significantly higher bone loss compared to the NC group (p = 0.0022). After 14 d, the OT (p < 0.0001) and OT + CSI (p < 0.0001) groups presented significantly higher bone loss compared to the NC group, and OT + CSI resulted in significantly higher bone loss than OT alone (p = 0.0241). The number of tartrate-resistant acid phosphatase-positive cells on the linear surface of the bone crest after 7 d was significantly higher in the OT + CSI group as compared to the NC and OT groups (p < 0.0001 and p = 0.0045, respectively) and remained significantly higher in the OT + CSI group after 14 d, compared to the OT group (p < 0.0001). Short-term CSI increases early bone loss in association with OT after 7 d, and this worsens in severity after 14 d of exposure. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  12. Association of Oxytocin and Parental Prefrontal Activation during Reunion with Infant: A Functional Near-Infrared Spectroscopy Study

    Jun Ito

    2017-12-01

    Full Text Available Although previous studies have revealed the role of oxytocin (OT in parental behavior, the role of OT has not been investigated through the direct assessment of prefrontal brain activation during parenting. By using functional near-infrared spectroscopy, we aimed to show the relationship between parental [maternal (N = 15 and paternal (N = 21] OT levels and the activation of the prefrontal cortex (PFC, while holding their infants after separation. Baseline OT levels were measured in the subjects’ saliva samples before the experiment. Prefrontal brain activation was assessed in participants sitting alone on a chair (i.e., separation from their infant for 120 s and during the target period (i.e., holding their infant for 45 s, which was done in triplicate. The oxygen hemoglobin (oxy-Hb dissociation curve significantly increased in 9 out of 22 channels on the PFC when maternal and paternal samples were combined. However, only the fathers showed a correlation between salivary OT and oxy-Hb signal. Furthermore, while holding their infants, high-OT fathers showed left hemispheric dominance compared to low-OT fathers, while high-OT mothers showed right hemispheric dominance compared to low-OT mothers. This study showed that fathers with high-OT levels showed neural activation with left hemispheric dominance, while holding their infants, suggesting that increase of OT level might activate paternal PFC related to parenting behavior, although the same is not true for mothers.

  13. Effect of different doses of oxytocin on cardiac electrophysiology and arrhythmias induced by ischemia.

    Houshmand, Fariba; Faghihi, Mahdieh; Imani, Alireza; Kheiri, Soleiman

    2017-01-01

    The onset of acute myocardial ischemia (MI) is accompanied by a rapid increase in electrical instability and often fatal ventricular arrhythmias. This study investigated that whether oxytocin (OT) can modulate ischemia-induced arrhythmias and considered relationships between the severity of arrhythmia and the electrocardiogram parameters during ischemia. OT (0.0001-1 μg) was administrated intraperitoneally 30 min before ischemia. To examine receptor involved, a selective OT-receptor antagonist, atosiban (ATO), was infused 10 min before OT. OT caused a significant and biphasic dose-dependent reduction in ectopic heart activity and arrhythmia score. OT doses that reduced ventricular arrhythmia elicited significant increase in QT interval. OT attenuated the electrophysiological changes associated with MI and there was significant direct relationship between QRS duration and arrhythmia score. ATO treatment reduced beneficial effects of OT on arrhythmogenesis. Nevertheless, ATO failed to alter OT effects on premature ventricular contractions. We assume that the ability of OT to modulate the electrical activity of the heart may play an important role in the antiarrhythmic actions of OT.

  14. Effect of different doses of oxytocin on cardiac electrophysiology and arrhythmias induced by ischemia

    Fariba Houshmand

    2017-01-01

    Full Text Available The onset of acute myocardial ischemia (MI is accompanied by a rapid increase in electrical instability and often fatal ventricular arrhythmias. This study investigated that whether oxytocin (OT can modulate ischemia-induced arrhythmias and considered relationships between the severity of arrhythmia and the electrocardiogram parameters during ischemia. OT (0.0001–1 μg was administrated intraperitoneally 30 min before ischemia. To examine receptor involved, a selective OT-receptor antagonist, atosiban (ATO, was infused 10 min before OT. OT caused a significant and biphasic dose-dependent reduction in ectopic heart activity and arrhythmia score. OT doses that reduced ventricular arrhythmia elicited significant increase in QT interval. OT attenuated the electrophysiological changes associated with MI and there was significant direct relationship between QRS duration and arrhythmia score. ATO treatment reduced beneficial effects of OT on arrhythmogenesis. Nevertheless, ATO failed to alter OT effects on premature ventricular contractions. We assume that the ability of OT to modulate the electrical activity of the heart may play an important role in the antiarrhythmic actions of OT.

  15. Oxytocin as a novel therapeutic option for type I diabetes and diabetic osteopathy.

    Elabd, S K; Sabry, I; Mohasseb, M; Algendy, A

    2014-04-01

    The aim of the present study was to highlight the newly discovered metabolic role of oxytocin (OT) in the type I diabetic rats. Previous studies have demonstrated that OT has a beneficial role on bone physiology and therefore, the OT effect on the diabetic osteopathy will be assessed as well. Induction of the type I diabetes was carried out by an intraperitoneal injection of 60 mg/kg body weight of streptozotocin. The metabolic role of OT on diabetic rats after OT treatment with intramuscular injection of 40 µIU/kg body weight for 6 weeks was assessed. Histological and ultrastructural studies of rat pancreas samples, before and after the OT injection, were performed and compared with the obtained physiological results. Oxytocin treatment had positive metabolic effects in diabetic rats. This is based on the change in glucose metabolism, lipid profile, and insulin sensitivity in experimental animals. In addition, OT treatment showed histological regenerative changes of pancreatic islet cells of diabetic rats. Moreover, OT administration showed that it has an anabolic effect on the bone biology. The results suggest that activation of the oxytocin receptor (OTR) pathway by infusion of OT, OT analogs, or OT agonists may represent a promising approach for the treatment of diabetes and some of its complications, including diabetic osteopathy.

  16. CSF and blood oxytocin concentration changes following intranasal delivery in macaque.

    Olga Dal Monte

    Full Text Available Oxytocin (OT in the central nervous system (CNS influences social cognition and behavior, making it a candidate for treating clinical disorders such as schizophrenia and autism. Intranasal administration has been proposed as a possible route of delivery to the CNS for molecules like OT. While intranasal administration of OT influences social cognition and behavior, it is not well established whether this is an effective means for delivering OT to CNS targets. We administered OT or its vehicle (saline to 15 primates (Macaca mulatta, using either intranasal spray or a nebulizer, and measured OT concentration changes in the cerebral spinal fluid (CSF and in blood. All subjects received both delivery methods and both drug conditions. Baseline samples of blood and CSF were taken immediately before drug administration. Blood was collected every 10 minutes after administration for 40 minutes and CSF was collected once post-delivery, at the 40 minutes time point. We found that intranasal administration of exogenous OT increased concentrations in both CSF and plasma compared to saline. Both delivery methods resulted in similar elevations of OT concentration in CSF, while the changes in plasma OT concentration were greater after nasal spray compared to nebulizer. In conclusion our study provides evidence that both nebulizer and nasal spray OT administration can elevate CSF OT levels.

  17. Oxytocin and vasopressin flatten dominance hierarchy and enhance behavioral synchrony in part via anterior cingulate cortex.

    Jiang, Yaoguang; Platt, Michael L

    2018-05-29

    The neuropeptides oxytocin (OT) and arginine vasopressin (AVP) influence social functions in many mammals. In humans and rhesus macaques, OT delivered intranasally can promote prosocial behavior in certain contexts. Yet the precise neural mechanisms mediating these behavioral effects remain unclear. Here we show that treating a group of male macaque monkeys intranasally with aerosolized OT relaxes their spontaneous social interactions with other monkeys. OT reduces differences in social behavior between dominant and subordinate monkeys, thereby flattening the status hierarchy. OT also increases behavioral synchrony within a pair. Intranasal delivery of aerosolized AVP reproduces the effects of OT with greater efficacy. Remarkably, all behavioral effects are replicated when OT or AVP is injected focally into the anterior cingulate gyrus (ACCg), a brain area linked to empathy and other-regarding behavior. ACCg lacks OT receptors but is rich in AVP receptors, suggesting exogenous OT may shape social behavior, in part, via nonspecific binding. Notably, OT and AVP alter behaviors of both the treated monkey and his untreated partner, consistent with enhanced feedback through reciprocal social interactions. These findings bear important implications for use of OT in both basic research and as a therapy for social impairments in neurodevelopmental disorders.

  18. Detection of Tropical Overshooting Cloud Tops Using Himawari-8 Imagery

    Miae Kim

    2017-07-01

    Full Text Available Abstract: Overshooting convective cloud Top (OT-accompanied clouds can cause severe weather conditions, such as lightning, strong winds, and heavy rainfall. The distribution and behavior of OTs can affect regional and global climate systems. In this paper, we propose a new approach for OT detection by using machine learning methods with multiple infrared images and their derived features. Himawari-8 satellite images were used as the main input data, and binary detection (OT or nonOT with class probability was the output of the machine learning models. Three machine learning techniques—random forest (RF, extremely randomized trees (ERT, and logistic regression (LR—were used to develop OT classification models to distinguish OT from non-OT. The hindcast validation over the Southeast Asia and West Pacific regions showed that RF performed best, resulting in a mean probabilities of detection (POD of 77.06% and a mean false alarm ratio (FAR of 36.13%. Brightness temperature at 11.2 μm (Tb11 and its standard deviation (STD in a 3 × 3 window size were identified as the most contributing variables for discriminating OT and nonOT classes. The proposed machine learning-based OT detection algorithms produced promising results comparable to or even better than the existing approaches, which are the infrared window (IRW-texture and water vapor (WV minus IRW brightness temperature difference (BTD methods.

  19. Salivary Oxytocin Concentrations in Males following Intranasal Administration of Oxytocin: A Double-Blind, Cross-Over Study.

    Daughters, Katie; Manstead, Antony S R; Hubble, Kelly; Rees, Aled; Thapar, Anita; van Goozen, Stephanie H M

    2015-01-01

    The use of intranasal oxytocin (OT) in research has become increasingly important over the past decade. Although researchers have acknowledged a need for further investigation of the physiological effects of intranasal administration, few studies have actually done so. In the present double-blind cross-over study we investigated the longevity of a single 24 IU dose of intranasal OT measured in saliva in 40 healthy adult males. Salivary OT concentrations were significantly higher in the OT condition, compared to placebo. This significant difference lasted until the end of testing, approximately 108 minutes after administration, and peaked at 30 minutes. Results showed significant individual differences in response to intranasal OT administration. To our knowledge this is the largest and first all-male within-subjects design study to demonstrate the impact of intranasal OT on salivary OT concentrations. The results are consistent with previous research in suggesting that salivary OT is a valid matrix for OT measurement. The results also suggest that the post-administration 'wait-time' prior to starting experimental tasks could be reduced to 30 minutes, from the 45 minutes typically used, thereby enabling testing during peak OT concentrations. Further research is needed to ascertain whether OT concentrations after intranasal administration follow similar patterns in females, and different age groups.

  20. Salivary Oxytocin Concentrations in Males following Intranasal Administration of Oxytocin: A Double-Blind, Cross-Over Study.

    Katie Daughters

    Full Text Available The use of intranasal oxytocin (OT in research has become increasingly important over the past decade. Although researchers have acknowledged a need for further investigation of the physiological effects of intranasal administration, few studies have actually done so. In the present double-blind cross-over study we investigated the longevity of a single 24 IU dose of intranasal OT measured in saliva in 40 healthy adult males. Salivary OT concentrations were significantly higher in the OT condition, compared to placebo. This significant difference lasted until the end of testing, approximately 108 minutes after administration, and peaked at 30 minutes. Results showed significant individual differences in response to intranasal OT administration. To our knowledge this is the largest and first all-male within-subjects design study to demonstrate the impact of intranasal OT on salivary OT concentrations. The results are consistent with previous research in suggesting that salivary OT is a valid matrix for OT measurement. The results also suggest that the post-administration 'wait-time' prior to starting experimental tasks could be reduced to 30 minutes, from the 45 minutes typically used, thereby enabling testing during peak OT concentrations. Further research is needed to ascertain whether OT concentrations after intranasal administration follow similar patterns in females, and different age groups.

  1. Oxytocin--its role in male reproduction and new potential therapeutic uses.

    Thackare, Hemlata; Nicholson, Helen D; Whittington, Kate

    2006-01-01

    Oxytocin (OT) is traditionally thought of as a "female" neurohypophysis hormone due to its role in parturition and milk ejection. However, OT is recognized as having endocrine and paracrine roles in male reproduction. At ejaculation, a burst of OT is released from the neurohypophysis into the systemic circulation and stimulates contractions of the reproductive tract aiding sperm release. There is conclusive evidence that OT is synthesized within the mammalian testis, epididymis and prostate and the presence of OT receptors (OTRs) through the reproductive tract supports a local action for this peptide. OT has a paracrine role in stimulating contractility of the seminiferous tubules, epididymis and the prostate gland. Interestingly, OT has also been shown to modulate androgen levels in these tissues via stimulation of the conversion of testosterone to dihydrotestostone (DHT) by 5alpha-reductase. The elucidation of OT's role in male reproduction has suggested a number of potential therapeutic uses for this hormone. Exogenous administration of OT has, in some cases, been shown to increase the numbers of ejaculated sperm, possibly by stimulating contractions of the reproductive tract and thus aiding sperm passage. Within the prostate, OT has been shown to affect gland growth both directly and via its interaction with androgen metabolism. Prostate pathologies due to unregulated cell proliferation/growth, such as benign prostatic hyperplasia and cancer, are unfortunately very common and few effective treatments are available. Greater understanding of paracrine growth mediators, such as OT, is likely to provide new mechanisms for treating such pathologies.

  2. Role of oxytocin in improving the welfare of farm animals - A review.

    Chen, Siyu; Sato, Shusuke

    2017-04-01

    Recently, increasing attention has been paid to the welfare of farm animals, which have been evaluated using behavioral and physiological measures. However, so far, the measures have almost always been used to estimate poor welfare. In this review, firstly we focus on how oxytocin (OT) relates to positive social behavior, pleasure, and stress tolerance, and second on which management factors stimulate OT release. OT induces maternal and affiliative behaviors and has an anti-stress effect. Further, OT is produced during enjoyable events, and has positive feedback on its own release as well. Therefore, to some extent, the relationship of OT to positive normal behavior was mutually beneficial-heightened OT concentration owing to comfortable rearing conditions induces positive social behavior, which in turn may increase OT concentration. Hence, studies on animal welfare should pay more attention to increasing comfort and the stress tolerance, rather than only focusing on when stress occurs in farm animals.

  3. Vasopressin and Oxytocin Reduce Food Sharing Behavior in Male, but Not Female Marmosets in Family Groups

    Jack H. Taylor

    2017-07-01

    Full Text Available Oxytocin (OT is critical for lactation and maternal care, but OT and the related nonapeptide vasopressin are important for caregiving behaviors in fathers and alloparents as well. This experiment tested the effects of vasopressin and OT on food sharing in marmoset families. We treated caregivers (parents, siblings with intranasal vasopressin, OT, or saline, and then paired them with the youngest marmoset in the family. Caregivers were given preferred food, and then observed for food sharing and aggressive behavior with young marmosets. OT reduced food sharing from male alloparents to youngest siblings, and fathers that received vasopressin refused to share food with their youngest offspring more often than when treated with OT. Vasopressin increased aggressive vocalizations directed toward potential food recipients in all classes of caregivers. These results indicate that vasopressin and OT do not always enhance prosocial behavior: modulation of food sharing depends on both sex and parental status.

  4. Dissociating frontal regions that co-lateralize with different ventral occipitotemporal regions during word processing☆

    Seghier, Mohamed L.; Price, Cathy J.

    2013-01-01

    The ventral occipitotemporal sulcus (vOT) sustains strong interactions with the inferior frontal cortex during word processing. Consequently, activation in both regions co-lateralize towards the same hemisphere in healthy subjects. Because the determinants of lateralisation differ across posterior, middle and anterior vOT subregions, we investigated whether lateralisation in different inferior frontal regions would co-vary with lateralisation in the three different vOT subregions. A whole brain analysis found that, during semantic decisions on written words, laterality covaried in (1) posterior vOT and the precentral gyrus; (2) middle vOT and the pars opercularis, pars triangularis, and supramarginal gyrus; and (3) anterior vOT and the pars orbitalis, middle frontal gyrus and thalamus. These findings increase the spatial resolution of our understanding of how vOT interacts with other brain areas during semantic categorisation on words. PMID:23728081

  5. Central oxytocin and food intake: focus on macronutrient-driven reward

    Anica eKlockars

    2015-04-01

    Full Text Available Centrally acting oxytocin (OT is known to terminate food consumption in response to excessive stomach distension, increase in salt loading and presence of toxins. Hypothalamic-hindbrain OT pathways facilitate these aspects of OT-induced hypophagia. However, recent discoveries have implicated OT in modifications of feeding via reward circuits: OT has been found to differentially affect consumption of individual macronutrients in choice and no-choice paradigms. In this mini-review, we focus on presenting and interpreting evidence that defines OT as a key component of mechanisms that reduce eating for pleasure and shape macronutrient preferences. We also provide remarks on challenges in integrating the knowledge on physiological and pathophysiological states in which both OT activity and macronutrient preferences are affected.

  6. Developmental toxicity of organotin compounds in animals

    Lijiao eWu

    2014-09-01

    Full Text Available Organotin compounds (OTs have been used as biocides in antifouling paints and agriculture. The IMO introduced a global ban on the use of OTs in antifouling systems in 2001 due to their high toxicity. However, OTs have still been detected in the environment and pose a threat to the ecosystem. Several research groups have summarized the analytical methods, environmental fate, biochemistry, reproductive toxicity and mechanisms of actions of OTs. Here, we reviewed the developmental toxicity of OTs in various organisms such as sea urchin, ascidian, mussel and fish. The differences in sensitivity to OT exposure exist not only in different species but also at different stages in the same species. Though some hypotheses have been proposed to explain the developmental toxicity of OTs, the solid evidences are greatly in need.

  7. Neuropeptide diversity and the regulation of social behavior in New World primates

    French, Jeffrey A.; Taylor, Jack H.; Mustoe, Aaryn C.; Cavanaugh, Jon

    2016-01-01

    Oxytocin (OT) and vasopressin (AVP) are important hypothalamic neuropeptides that regulate peripheral physiology, and have emerged as important modulators of brain function, particularly in the social realm. OT structure and the genes that ultimately determine structure are highly conserved among diverse eutherian mammals, but recent discoveries have identified surprising variability in OT and peptide structure in New World monkeys (NWM), with five new OT variants identified to date. This review explores these new findings in light of comparative OT/AVP ligand evolution, documents coevolutionary changes in the oxytocin and vasopressin receptors (OTR and V1aR), and highlights the distribution of neuropeptidergic neurons and receptors in the primate brain. Finally, the behavioral consequences of OT and AVP in regulating NWM sociality are summarized, demonstrating important neuromodulatory effects of these compounds and OT ligand-specific influences in certain social domains. PMID:27020799

  8. Thermal And Gamma-Radiation Annealing Of The Iridium-192 Recoil Species In Crystalline Na{sub 2}IrCl{sub 6} {center_dot} 6H{sub 2}O; Recuit Thermique et par Rayonnement Gamma de l'espece {sup 192}Ir de Recul dans des Cristaux de Na{sub 2}IrCl{sub 6} * 6H{sub 2}O; 0422 0415 041f 041b 041e 0412 041e 0419 0418 0413 0410 041c 041c 0410 - 041e 0422 0416 0418 0413 041f 0420 041e 0414 0423 041a 0422 041e 0412 041e 0422 0414 0410 0427 0418 0418 0420 0418 0414 0418 042f -192 0412 041a 0420 0418 0421 0422 0410 041b 041b 0418 0427 0415 0421 041a 041e 041c Na{sub 2}IrCl{sub 6} {center_dot} 6H{sub 2}O; Regeneracion Termica y por Irradiacion Gamma de las Especies de Retroceso del Iridio-192 en Na{sub 2}IrCl{sub 6} {center_dot} 6H{sub 2}O Cristalino

    Bell, Rita; Herr, W. [Kernforschungsanlage Juelich, Institut fuer Kernchemie der Universitaet Koeln, Cologne, Federal Republic of Germany (Germany)

    1965-04-15

    bol'shinstvo iz nih imeet anionnyj harakter, dva vystupajut v kachestve kationov, mechennyh Ir{sup 192}. Izuchalos' povedenie jetih svobodnyh ot nositelja soedinenij po otnosheniju k vosstanoviteljam i okisliteljam i ih starenie v rastvore. Nezavisimo ot jetogo byl issledovan gidroliz geksahloridn'hh kompleksov treh- i chetyrehvalentnogo iridija, mechennyh Cl{sup 36} i Ir{sup 192} . Sravnenie jetih dvuh serij rezul'tatov, podkreplennoe posledujushhimi rezul'tatami, poluchennymi pri nejtronnom aktivacionnom analize, daet vozmozhnost' obnaruzhit', chto bol'shaja chast' produktov otdachi sushhestvuet v vide oktajedricheskih kompleksov Ir-III, soderzhashhih razlichnye kolichestva Cl{sup -}, H{sub 2}O i OH{sup -} v kachestve ligandov. Po vsej vidimosti, kristallizacionnaja voda igraet vazhnuju rol' v formirovanii soedinenija otdachi. Teplovoj otzhig jetih produktov pri temperature 120 Degree-Sign C privodit k bystromu umen'sheniju vyhoda akvohlor-, gidrohlor- i akvogidroksohlorkompleksov po sravneniju s obrazovaniem ishodnogo soedinenija. Iskljucheniem javljaetsja pentahlorkompleks, vyhod kotorogo umen'shaetsja tol'ko posle pervonachal'nogo uvelichenija, chto ukazyvaet na to, chto on javljaetsja promezhutochnym sredi drugih produktov, obrazujushhihsja vo vremja otzhiga. Gamma-radiacionnyj otzhig pokazyvaet mnogie prostye stadii processa, obshhej tendenciej kotoryh javljaetsja perehod ot kompleksov s men'shim kolichestvom Cl k kompleksam, soderzhashhim gorazdo bol'shee kolichestvo Cl, chto v konechnom schete privodit k obrazovaniju geksahlor kompleksa. Jeto pokazyvaet, chto v processe otzhiga v ligandnuju sferu vhodjat dopolnitel'nye atomy (ili iony) hlora, zameshhaja H{sub 2}O, a takzhe ON (ON-). (author)

  9. The acute effects of intranasal oxytocin administration on endocrine and sexual function in males.

    Burri, Andrea; Heinrichs, Markus; Schedlowski, Manfred; Kruger, Tillmann H C

    2008-06-01

    The role of the neuropeptide oxytocin (OT) ranges from the modulation of neuroendocrine physiological effects to the establishment of complex social and bonding behaviours. Experimental studies in animals, as well as case reports in humans, suggest that OT affects different aspects of sexual behaviour and has predominantly facilitating properties for sexual appetence and performance. Using a previously established experimental paradigm of sexual arousal and masturbation-induced orgasm, this study investigated the acute effects of intranasal OT application (24I.U.) on endocrine parameters and measures of sexual appetence and function in healthy men (n=10). In a double-blind, placebo-controlled, balanced cross-over design, sexual arousal, and orgasm were induced by an erotic film and masturbation. In addition to the continuous recording of endocrine (OT, cortisol, prolactin, epinephrine, norepinephrine) and cardiovascular data (heart rate), parameters of appetitive, consummatory, and refractory sexual behaviour were assessed using the acute sexual experience scale (ASES). OT plasma levels were significantly elevated after intranasal OT throughout the whole experiment (>60 min). In addition, OT treatment induced significantly higher increases in epinephrine plasma levels during sexual activity without affecting cortisol levels, prolactin levels or heart rate. OT treatment did not alter appetitive, consummatory, and refractory sexual behaviour according to the ASES. However, when subjects were asked about their subjective perception of whether OT or placebo had been applied, eight out of 10 subjects in the OT group answered correctly, thus pointing to an altered perception of arousal. In conclusion, intranasally administered OT leads to a marked increase in OT plasma levels together with increased secretion of catecholamines when subjects are engaged in sexual activity in a laboratory setting. As the effects of OT on sexual behaviour were equivocal, future studies

  10. Distinct BOLD activation profiles following central and peripheral oxytocin administration in awake rats

    Craig F Ferris

    2015-09-01

    Full Text Available A growing body of literature has suggested that intranasal oxytocin (OT or other systemic routes of administration can alter prosocial behavior, presumably by directly activating OT sensitive neural circuits in the brain. Yet there is no clear evidence that OT given peripherally can cross the blood-brain-barrier at levels sufficient to engage the OT receptor. To address this issue we examined changes in blood oxygen level dependent (BOLD signal intensity in response to peripheral OT injections (0.1, 0.5 or 2.5 mg/kg during functional magnetic resonance (fMRI in awake rats imaged at 7.0 tesla. These data were compared to OT (1ug/5 µl given directly to the brain via the lateral cerebroventricle. Using a 3D annotated MRI atlas of the rat brain segmented into 171 brain areas and computational analysis we reconstructed the distributed integrated neural circuits identified with BOLD fMRI following central and peripheral OT. Both routes of administration caused significant changes in BOLD signal within the first 10 min of administration. As expected, central OT activated a majority of brain areas known to express a high density of OT receptors e.g., lateral septum, subiculum, shell of the accumbens, bed nucleus of the stria terminalis. This profile of activation was not matched by peripheral OT. The change in BOLD signal to peripheral OT did not show any discernible dose-response. Interestingly, peripheral OT affected all subdivisions of the olfactory bulb, in addition to the cerebellum and several brainstem areas relevant to the autonomic nervous system, including the solitary tract nucleus. The results from this imaging study do not support a direct central action of peripheral OT on the brain. Instead, the patterns of brain activity suggest that peripheral OT may interact at the level of the olfactory bulb and through sensory afferents from the autonomic nervous system to influence brain activity.

  11. Operating theatre ventilation systems and microbial air contamination in total joint replacement surgery: results of the GISIO-ISChIA study.

    Agodi, A; Auxilia, F; Barchitta, M; Cristina, M L; D'Alessandro, D; Mura, I; Nobile, M; Pasquarella, C

    2015-07-01

    Recent studies have shown a higher rate of surgical site infections in hip prosthesis implantation using unidirectional airflow ventilation compared with turbulent ventilation. However, these studies did not measure the air microbial quality of operating theatres (OTs), and assumed it to be compliant with the recommended standards for this ventilation technique. To evaluate airborne microbial contamination in OTs during hip and knee replacement surgery, and compare the findings with values recommended for joint replacement surgery. Air samplings were performed in 28 OTs supplied with unidirectional, turbulent and mixed airflow ventilation. Samples were collected using passive sampling to determine the index of microbial air contamination (IMA). Active sampling was also performed in some of the OTs. The average number of people in the OT and the number of door openings during the sampling period were recorded. In total, 1228 elective prosthesis procedures (60.1% hip and 39.9% knee) were included in this study. Of passive samplings performed during surgical activity in unidirectional airflow ventilation OTs (U-OTs) and mixed airflow OTs (M-OTs), 58.9% and 87.6% had IMA values >2, respectively. Of samplings performed during surgical activity in turbulent airflow OTs (T-OTs) and in turbulent airflow OTs with the surgical team wearing Steri-Shield Turbo Helmets (TH-OTs), 8.6% and 60% had IMA values ≤ 2, respectively. Positive correlation was found between IMA values and the number of people in the OT and the number of door openings (P systems always provide acceptable airborne bacterial counts. Copyright © 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  12. Body temperature and cardiac changes induced by peripherally administered oxytocin, vasopressin and the non-peptide oxytocin receptor agonist WAY 267,464: a biotelemetry study in rats

    Hicks, C; Ramos, L; Reekie, T; Misagh, G H; Narlawar, R; Kassiou, M; McGregor, I S

    2014-01-01

    Background and Purpose There is current interest in oxytocin (OT) as a possible therapeutic in psychiatric disorders. However, the usefulness of OT may be constrained by peripheral autonomic effects, which may involve an action at both OT and vasopressin V1A receptors. Here, we characterized the cardiovascular and thermoregulatory effects of OT, vasopressin (AVP) and the non-peptide OT receptor agonist WAY 267,464 in rats, and assessed the relative involvement of the OT and V1A receptors in these effects. Experimental Approach Biotelemetry in freely moving male Wistar rats was used to examine body temperature and heart rate after OT (0.01 – 1 mg kg−1; i.p.), AVP (0.001 – 0.1 mg kg−1; i.p.) or WAY 267,464 (10 and 100 mg kg−1; i.p.). The actions of the OT receptor antagonist Compound 25 (C25, 5 and 10 mg kg−1) and V1A receptor antagonist SR49059 (1 and 10 mg kg−1) were studied, as well as possible V1A receptor antagonist effects of WAY 267,464. Key Results OT and AVP dose-dependently reduced body temperature and heart rate. WAY 267,464 had similar, but more modest, effects. SR49059, but not C25, prevented the hypothermia and bradycardia induced by OT and AVP. WAY 267,464 (100 mg·kg−1) prevented the effects of OT, and to some extent AVP. Conclusions and Implications Peripherally administered OT and AVP have profound cardiovascular and thermoregulatory effects that appear to principally involve the V1A receptor rather than the OT receptor. Additionally, WAY 267,464 is not a simple OT receptor agonist, as it has functionally relevant V1A antagonist actions. PMID:24641248

  13. Body temperature and cardiac changes induced by peripherally administered oxytocin, vasopressin and the non-peptide oxytocin receptor agonist WAY 267,464: a biotelemetry study in rats.

    Hicks, C; Ramos, L; Reekie, T; Misagh, G H; Narlawar, R; Kassiou, M; McGregor, I S

    2014-06-01

    There is current interest in oxytocin (OT) as a possible therapeutic in psychiatric disorders. However, the usefulness of OT may be constrained by peripheral autonomic effects, which may involve an action at both OT and vasopressin V1A receptors. Here, we characterized the cardiovascular and thermoregulatory effects of OT, vasopressin (AVP) and the non-peptide OT receptor agonist WAY 267,464 in rats, and assessed the relative involvement of the OT and V1A receptors in these effects. Biotelemetry in freely moving male Wistar rats was used to examine body temperature and heart rate after OT (0.01 - 1 mg kg(-1); i.p.), AVP (0.001 - 0.1 mg kg(-1); i.p.) or WAY 267,464 (10 and 100 mg kg(-1); i.p.). The actions of the OT receptor antagonist Compound 25 (C25, 5 and 10 mg kg(-1)) and V1A receptor antagonist SR49059 (1 and 10 mg kg(-1)) were studied, as well as possible V1A receptor antagonist effects of WAY 267,464. OT and AVP dose-dependently reduced body temperature and heart rate. WAY 267,464 had similar, but more modest, effects. SR49059, but not C25, prevented the hypothermia and bradycardia induced by OT and AVP. WAY 267,464 (100 mg·kg(-1)) prevented the effects of OT, and to some extent AVP. Peripherally administered OT and AVP have profound cardiovascular and thermoregulatory effects that appear to principally involve the V1A receptor rather than the OT receptor. Additionally, WAY 267,464 is not a simple OT receptor agonist, as it has functionally relevant V1A antagonist actions. © 2014 The British Pharmacological Society.

  14. Aktuální otázky používání zahraničního práva v soudním a rozhodčím řízení

    Pauknerová, Monika

    2012-01-01

    Roč. 151, č. 12 (2012), s. 1265-1290 ISSN 0231-6625 Institutional support: RVO:68378122 Keywords : private international law * treatment of foreign law * arbitral proceedings Subject RIV: AG - Legal Sciences

  15. Přehled kulturních, literárních a školních otázek aneb Svědectví o vkladu české menšiny v Chorvatsku do české a chorvatské vědy

    Pánek, Jaroslav

    2017-01-01

    Roč. 35, č. 1 (2017), s. 97-109 ISSN 1330-3880 Institutional support: RVO:67985963 Keywords : Czech Minorities * Croatia * Sciences Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  16. Conolly, R.B., Ankley, G.T., Cheng, WY., Mayo, M.L., Miller, D.H., Perkins, E.J., Villeneuve, D.L., and Watanable, K.H. (2017). Quantitative adverse outcome pathways and their application ot predictive toxicology. Environ. Sci. Technol. 51, 4661–4672

    U.S. Environmental Protection Agency — A publised mansucript describing a quantitative adverse outcome pathway (qAOP) and its relevance to risk assessment. This dataset is not publicly accessible because:...

  17. Nezájem pověřených. Přístup českých politiků a političek, úředníků a úřednic k otázkám genderové rovnosti

    Křížková, Alena

    2006-01-01

    Roč. 7, č. 2 (2006), s. 37-41 ISSN 1213-0028 R&D Projects: GA AV ČR 1QS700280503 Institutional research plan: CEZ:AV0Z70280505 Keywords : gender equality legislation * EU Eastern enlargement * attitudes of officals and politicians to gender issues Subject RIV: AO - Sociology, Demography http://www. gender online.cz

  18. Středoevropské bezlesí v čase a prostoru. V. Otázka přirozeného bezlesí v českých zemích a na Slovensku

    Ložek, Vojen

    2004-01-01

    Roč. 59, č. 6 (2004), s. 169-175 ISSN 1210-258X Institutional research plan: CEZ:AV0Z3013912 Keywords : Woodland * Open Country * Human Impact Subject RIV: DB - Geology ; Mineralogy http://www.casopis.ochranaprirody.cz/res/data/003/000467.pdf

  19. Organization of measures on protection of population and territories against weapons of mass destruction: brief analysis of laboratory control and conditions of personnel protective means of respiratory organs in the Republic of Tajikistan; Organizatsiya meropriyatiy po zashite naseleniya i territoriy ot oruzhiya massovogo unichtozheniya; kratkiy analiz laborotornogo kotrolya i sostoyaniya sredstv individual'noy zashiti organov dikhaniya v Respublike Tadzhikistan

    Kamalov, D. D.; Makhmadov, T. F.; Stotskiy, D. F. [Committee of Emergency Situations and Civil Defence under the Government of the Republic of Tajikistan, Dushanbe (Tajikistan)

    2010-07-01

    Full text: Changing of character of acts of terrorism in the end of 20 and the beginning of 21 centuries specifies the increased interest of the terrorist organizations to the weapons of mass destruction. The most accessible are the biological and chemical weapons, as well as the self-made {sup d}irty{sup e}xplosive devices filled with a radioactive material. Application by terrorists of the nuclear weapon at the present is not actual. A nuclear ammunition is under the intensive control not only of the state-possessor of the nuclear weapon, but also all world community. Benefit of use of mass destruction weapons by the terrorist organizations is depended of accessibility of combat chemical or biological substances, easiness of their manufacture, a small amount of poisoning and biological substances necessary for use in the closed space, availability of influence on the big areas, psychological pressure upon the world community. The most known incidents related with use of chemical or biological substances were: - 1992 (chemical) - neo nazis attacked synagogue using cyanide, Germany - 1993 (chemical) - cyanide inside the bomb exploded in the World Trade Center, USA - 1994 (chemical) - use of sarin in Matsumoto, Japan led to the death of 8 and hospitalization of 200 people - 1995 (chemical) - again sarin used in Tokyo metro, 12 people died and 5 500 injured - 1995 (chemical) - FBI agents prevented the attack with the use of sarin of Disney land - 1995 (chemical) - attack in Japan with use of cyanide, phosgene and pepper gas - 1995 (biological) - a member of 'Aryan nation' was arrested for ordering a pestilence virus. - 1995 (radiological) - a terrorist organization of Chechnya republic placed a 14 kilo pack filled with a radioactive cesium-137 and explosives in a Moscow park - 1997 (chemical) - 2 attacks of the trading centers with a use of chlor bombs in Japan. The facts mentioned above put before the Republic of Tajikistan objectives of organization of actions for population and territory protection from mass-destruction weapon. Organization of actions on population and territory protection is caused on geographical location of Tajikistan. There is a number of some states near Tajikistan that have nuclear weapon: India, China, Pakistan. The basic actions for protection of the population and territories from weapons of mass destruction are: maintenance and accumulation of means of an individual defense, creation of stocks; creation and restoration of protective constructions of a civil defense; evacuation actions planning; restoration of system of monitoring and the laboratory control of a civil defense of Republic Tajikistan; according to the Government Regulation N 527 and dated on 31{sup st} of October, 2008 the 'Emergency situations and civil defense system development 2009-2014' Program was adopted. According to the Plan of the events within this Programme Committee of emergency situations and civil defense under the Government of Republic of Tajikistan provides a stage-by-stage realization of the actions for protection of population and territories from mass-destruction weapon. One of the important actions is provision and accumulation of the means of personal protection, keeping of this means. The means of personal protections are laboratory tested by the specialists of the Committee of emergency situations and civil defense. Analytical data of the Committee of emergency situations and civil defense allows making some conclusions concerning experienced storage of the means of personal protection. A general analysis of laboratory test indicates that: laboratory tests of filtering boxes indicate the preservation of air flow resistance and waterproof due to the adherence to the rules of keeping; laboratory tests of the front parts of the gas masks and their hardness and waterproof, and the waterproof of the valves show that the front part is dependent on meteorological character of the region of storage at long-term keeping. Conclusions: According to the experience, personal protection equipment kept due to the rules of storage can keep its technical characteristics.

  20. Riigivõimu ülesannete üleandmine eraõiguslikele isikutele vabakutseliste kohtutäiturite näitel : [bakalaureusetöö] / Elin Palts ; Tartu Ülikooli Õigusinstituut ; juhendajad: Jaanus Ots, Kaire Pikamäe

    Palts, Elin

    2003-01-01

    Avaliku halduse reformi mõiste, avalike ülesannete eraõiguslikele isikutele üleandmise erinevad mudelid, täitevsüsteemi reform, avalik-õiguslike nõuete jaotamine kohtutäiturite vahel, lisateenuste osutamine kohtutäiturite poolt

  1. Copolymerization of Ethylene Induced by Cobalt-60 Gamma Radiation; Copolymerisation de l'ethylene induite par des rayons gamma du cobalt-60; Sopolimerizatsiya ehtilena pod dejstviem gamma-izlucheniya ot istochnika ks'yali-60; Copolimerizacion del etileno inducida por las radiaciones gamma del cobalto-60

    Steinberg, M.; Colombo, P. [Brookhaven National Laboratory, Long Island, NY (United States)

    1963-11-15

    The gamma radiation initiated copolymerization of ethylene with a number of different monomers was studied at 20{sup o}C and initial pressures up to 680 atm. The experiments were conducted statically in two-phase systems with the exception of the ethylene-carbon monoxide system. Isolation of the copolymers was effected by solvent extraction and fractional precipitation techniques. Infra-red spectroscopy was used for identification. The composition was determined by elemental analysis. A partial evaluation of some of the reaction products including crystalline melting points, densities, solubility characteristics, and molecular weights are given. Evidence of ethylene copolymerization was established with each of the following monomers: styrene, methyl methacrylate, vinyl acetate, acrylonitrile, allyl acetate, isobutylene, chlorotrifluoroethylene, trans 2-butene, methyl acrylate, isoprene, propylene, vinyl chloride, 1-butene, cis 2-butene, carbon monoxide, vinyl pyrrolidone, methyl vinyl ketone, and divinyl benzene. The experimental data obtained in the study of the ethylene-carbon monoxide system were found to obey a linear form of the copolymer composition equation. The ratio of specific rate constants for carbon monoxide and ethylene ({alpha}) was found to have a value of 22.0, indicating that carbon monoxide as a monomer, is activated to the extent that it adds 22 times as fast as an ethylene monomer to an ethylene free-radical chain end. Explosive decomposition was observed to occur during irradiation of ethylene arid chlorotrifluoroethylene under certain irradiation conditions. There is an indication that a threshold radiation intensity exists which induces this violent reaction. The unique advantage of cobalt-60 gamma radiation is that it can be used to induce and control ethylene copolymerization reactions at low temperatures. (author) [French] La copolymerisation de l'ethylene avec divers monomeres provoquee avec des rayons gamma a ete etudiee a 20{sup o}C et a des pressions initiales allant jusqu'a 680 atm. On a procede aux experiences, en milieu statique, dans des systemes a deux phases, a l'exception du systeme ethylene-oxyde de carbone. La separation des copolymeres a ete obtenue par des methodes d'extraction par solvant et de precipitation fractionnee. L'identification a ete faite au moyen de la spectroscopic aux infrarouges. La composition a ete determinee par analyse elementaire. Les auteurs donnent une evaluation partielle de certains produits de la reaction, y compris les points de fusion cristalline, les densites, les caracteristiques de solubilite et les poids moleculaires. La copolymerisation de l'ethylene a ete etablie avec chacun des monomeres suivants : styrene, methacrylate de methyle, acetate de vinyle, acrylonitrile, acetate d'allyle, isobutylene, chlorotiifluoroethylene, transbutene-2, acrylate de methyle, isoprene, propylene, chlorure de vinyle, butene-1, cis-butene-2, oxyde de carbone, pyrrolidone de vinyle, methyle- vinyle-cetone et divinyle-benzene. Les auteurs ont trouve que les donnees experimentales obtenues dans l'etude du systeme ethylene-oxyde de carbone suivaient une forme lineaire de l'equation de composition du copolymere. Pour le rapport {alpha} des constantes de vitesse specifiques de l'oxyde de carbone et de l'ethylene, ils ont determine la valeur 22,0, ce qui montre que l'oxyde de carbone en tant que monomere est active a tel point qu'il se fixe a l'extremite d'une chaftie de radicaux libres d'ethylene 22 fois plus vite que ne le fait un monomere d'ethylene. (author) [Spanish] Los autores estudiaron la copolimerizacion del etileno, inducida por las radiaciones gamma, con una serie de diversos monometos, a 20{sup o}C y presiones iniciales de hasta 680 atm. Los experimentos se llevaron a cabo estaticamente en sistemas bifasicos, salvo en el caso del etileno-oxido de carbono. La separacion de los copolimeros se llevo a cabo por extraccion mediante disolventes y por precipitacion fraccionada. La identificacion se efectuo por espectroscopia infrarroja y la composicion se determino por analisis elemental. Para algunos de los productos de reaccion, los autores indican los puntos de fusion cristalinos, las densidades, las caracteristicas de solubilidad y los pesos moleculares. Obtuvieron pruebas de la copolimerizacion del etileno con cada uno de los siguientes monomeros: estireno, metacrilato de metilo, acetato de vinilo, acrilonitrilo, acetato de alilo, isobuteno, clorotrifluoretileno, trans 2-buteno, acrilato de metilo, isopreno, propeno, cloruro de vinilo, 1-buteno, cis 2-buteno, oxido de carbono, vinilpirrolidona, metilvinilcetona y divinilbenceno. Comprobaron que los datos experimentales obtenidos en el estudio del sistema etileno-oxido de carbono responden a una forma lineal de la ecuacion de composicion del copolimero. Encontraron el valor 22,0 para la razon ({alpha}) de las constantes de velocidad especificas correspondientes al oxido de carbono y al etileno, respectivamente, lo que indica que en calidad de monomero el oxido de carbono se activa en tal medida que se fija al extremo de una cadena de radical etilenico libre con una velocidad 22 veces mayor que un monomero etilenico. (author) [Russian] Byla izuchen vyzvannaya gamma-izlucheniem sopolimerizatsiya ehtilena s ryadom razlichnykh monomerov pri temperature 20{sup o}C i pri nachal'nykh davleniyakh do 680 atm. Ehksperimenty provodilis' staticheski v dvukhfaznykh sistemakh, za isklyucheniem sistemy ehtilen-okis' ugleroda. Razdelenie sopolimerov proizvodilos' metodami ehkstraktsii rastvoritelem i fraktsionirovannogo osazhdeniya. Dlya identifikatsii ispol'zovali infrakrasnuyu spektroskopiyu, a dlya opredeleniya sostava - ehlementarnyj analiz. Privedeny kharakte- ristiki nekotorykh produktov reaktsii, vklyuchayushchie ikh temperaturu plavleniya, plotnost', rastvorimost' i molekulyarnyj ves. Ustanovlena sopolimerizatsiya ehtilena s kazhdym iz sleduyushchikh monomerov: stirolom, metilmetakrilatom, venilatsetatom, akrilonitrilom, allilatsetatom, izobutilenom, khlorotriftoroehtilenom, trans-2-butenom, metilakrilatom, izoprenom, propilenom, khloristym vinilom, 1-butenom, tsis-2-butenom, okis'yu ugleroda, vinilpirrolidonom, metilvinilketonom i divinilbenzolom. Ustanovleno, chto dannye,-poluchennye ehksperimental'nym putem pri izuchenii, sistemy ehtilen-okis' ugleroda, udovletvoryayut linejnoj forme uravneniya sostava sopolimera. Ustanovleno, chto otnoshenie konstant udel'nykh skorostej dlya okisi ugleroda i ehtilena ({alpha}) sostavlyaet 22,0, chto oznachaet, chto okis' uglerode kak monomer aktivirovana v takop stepeni, chto ona prisoedinyaetsya k kontsu tsepochki svobodnykh radikalov ehtilena v 22 raza bystree chem ehtilenovyj monomer. (author)

  2. Results of a jet plume effects test on Rockwell International integrated space shuttle vehicle using a vehicle 5 configuration 0.02-scale model (88-OTS) in the 11 by 11 foot leg of the NASA/Ames Research Center unitary plan wind tunnel (IA19), volume 1

    Nichols, M. E.

    1975-01-01

    Results are presented of jet plume effects test IA19 using a vehicle 5 configuration integrated space shuttle vehicle 0.02-scale model in the NASA/Ames Research Center 11 x 11-foot leg of the unitary plan wind tunnel. The jet plume power effects on the integrated vehicle static pressure distribution were determined along with elevon, main propulsion system nozzle, and solid rocket booster nozzle effectiveness and elevon hinge moments.

  3. Otázka stáří nejvyšší části líňského souvrství (mšensko-roudnická pánev, Český masiv) – nové indicie z vrtu Be-1 Bechlín

    Zajíc, Jaroslav

    2012-01-01

    Roč. 2011, podzim (2012), s. 59-62 ISSN 0514-8057 R&D Projects: GA AV ČR IAA300130703 Institutional research plan: CEZ:AV0Z30130516 Keywords : Mšeno-Roudnice Basin * Carboniferous/ Permian boundary * Líně Formation * zoopalaeontology * biostratigraphy Subject RIV: DB - Geology ; Mineralogy http://www.geology.cz/zpravy/obsah/2011/zpravy_2011-13.pdf

  4. K otázkám některých základních lidských práv a svobod v souvislosti s právní ochranou biometrických údajů

    Güttler, Vojen; Matejka, Ján

    2016-01-01

    Roč. 155, č. 12 (2016), s. 1033-1056 ISSN 0231-6625 R&D Projects: GA ČR(CZ) GA16-26910S Institutional support: RVO:68378122 Keywords : biometric data * sensitive personal data * private life Subject RIV: AG - Legal Sciences OBOR OECD: Law

  5. K otázce datování počátků kultury s keramikou pražského typu na Moravě. Příspěvek pro 15. mezinárodní sjezd slavistů v Minsku

    Jelínková, Dagmar

    2012-01-01

    Roč. 53, č. 2 (2012), s. 7-21 ISSN 1211-7250 R&D Projects: GA ČR GA404/07/1629 Institutional support: RVO:68081758 Keywords : Prague-type-pottery culture * Southern Moravia * inhumation grave * sax * settlement * dating C14 Subject RIV: AC - Archeology, Anthropology, Ethnology http://dino.iabrno.cz/dokumenty/pv/PV53_2_studie/PV53_2_studie_1.pdf

  6. Thermodynamic properties of britholites CaxLay(SiO4)6-u(PO4)uOt, study of the properties of diffusion and fixation of lanthanide and trans-uranian ions in britholites: application in the field of luminescent materials and of storage of nuclear wastes

    El Ouenzerfi, R.

    2003-02-01

    This work deals in particular with the synthesis and the characterization of the apatitic oxy-silico-phosphates. In a first part is studied the quaternary system: CaO-La 2 O 3 -SiO 2 P 2 O 5 in order to determine the range in which the pure phospho-silicated apatites exist. Then, the obtained phases have been identified and characterized by chemical analysis methods, electron microprobe analysis, X-ray diffraction, infrared and Raman spectroscopies. The study of the uranium solubilization and diffusion in apatitic matrices has been carried out from the determination of the substitution limit, of the oxidation degree and of the diffusion coefficient of uranium in a phospho-silicated apatite. In a second part, the luminescence properties of the Eu 3+ and Ce 3+ ions in phospho-silicated apatites have been studied. This work allows to have a wider vision of the oxy-silico-phosphated apatites and of their synthesis conditions. The study of the physical and chemical properties of britholites doped with actinides or lanthanides ions will be useful to the study of the optical properties of these matrices. (O.M.)

  7. Možnosti využití jednoduché sebehodnoticí otázky pro měření úrovně pracovního stresu v průřezových dotazníkových šetřeních kvality pracovního života

    Vinopal, Jiří

    2011-01-01

    Roč. 5, č. 2 (2011), s. 35-57 ISSN 1802-8152 Institutional research plan: CEZ:AV0Z70280505 Keywords : working stress measurement * quality of working life * SQWL Subject RIV: AO - Sociology, Demography

  8. Právní otázky související s problematikou translidí pod zorným úhlem rozhodnutí Velkého senátu ESLP ve věci Hämäläinen vs Finsko

    Doležal, Adam

    2014-01-01

    Roč. 4, č. 3 (2014), s. 44-60 ISSN 1804-8137 R&D Projects: GA ČR(CZ) GA14-35646S Institutional support: RVO:68378122 Keywords : transgender * marriage * registered partnership Subject RIV: AG - Legal Sciences http://www.ilaw.cas.cz/medlawjournal/index.php/medlawjournal/article/view/82/80

  9. Identification and estimation ot carbohydrates using radioisotopic methods; Identification et dosage des hydrates de carbone a l'aide des radioisotopes; Identifikatsiya i opredelenie karbogidratov s pomoshch'yu radioizotopnykh metodov; Identificacion u valoracion de hidratos de carbono con ayuda de radioisotopos

    Phillips, G O; Criddle, W J [Department of Chemistry, University College, Cardiff (United Kingdom)

    1962-01-15

    Isotope-dilution methods have been developed to identify and estimate the small amount of products formed when carbohydrates are irradiated in aqueous solution with Co{sup 60} gamma-radiation. Conventional analytical methods proved inadequate. After irradiation of C{sup 14}-sugar solutions, the autoradiographs prepared after paper chromatography indicated extensive degradation. Using a reverse isotope-dilution procedure involving the addition of known carriers, and conversion of the fragments into crystalline derivatives, various constituents were quantitatively determined. It is possible to distinguish between d- and Z-isomers, and estimate each isomer independently. The method is applicable to other analytical problems in carbohydrate chemistry. A new method for scanning and recording the radioactivity along paper-chromatogram strips, which involves an inexpensive modification to conventional counting equipment, is described. (author) [French] On a mis au point des methodes de dilution isotopique destinees a identifier et a doser les menues quantites de produits qui se forment lorsque des hydrates de carbone en solution aqueuse sont irradies par les rayons gamma du cobalt-60. A cet egard, les methodes d'analyse classiques se sont revelees inadequates. Apres irradiation de solutions de sucre marque au carbone-14, les autoradiogrammes etablis a la suite d'une chromatographic sur papier indiquaient une forte degradation. En recourant a une methode de dilution isotopique inverse, avec adjonction d'entraineurs connus, et en operant une conversion des fragments en derives cristallins, on a pu determiner quantitativement plusieurs elements constitutifs. Il est possible de distinguer les isomeres dextrogyres des isomeres levogyres et de doser chaque isomere independamment. La methode peut etre appliquee a d'autres problemes d'analyse dans la chimie des hydrates de carbone. Le memoire decrit une nouvelle methode permettant d'explorer et d'enregistrer la radioactivite de chromatogrammes sur bandes de papier; elle n'exige qu'une modification peu couteuse du materiel de comptage traditionnel. (author) [Spanish] Dado que los metodos analiticos clasicos no permiten obtener resultados satisfactorios, los autores han perfeccionado unos metodos de dilucion isotopica para identificar y valorar los productos que se forman en pequenas cantidades al exponer hidratos de carbono en solucion acuosa a las radiaciones gamma del {sup 60}Co. Las autorradiografias de cromatogramas sobre papel, obtenidos despues de irradiar soluciones de azucares marcados con {sup 14}C, revelan una considerable degradacion molecular. Gracias a un metodo de dilucion isotopica inverso basado en la adicion de portadores conocidos, y en la obtencion de derivados cristalizados de los fragmentos, los autores han podido determinar cuantitativamente los siguientes constituyentes. El metodo descrito por los autores permite distinguir entre estereoisomeros y valorar cada lino de ellos por separado. Asimismo puede utilizarse para resolver otros problemas de orden analitico que plantea la quimica de los hidratos de carbono. Los autores describen un nuevo metodo de exploracion y registro de la radiactividad a lo largo de las tiras de papel en las que se ha desarrollado el cromatograma. Este metodo solo requiere una modificacion poco onerosa del equipo de recuento corriente. (author) [Russian] Dlya identifikatsii i otsenki nebol'shikh kolichestv obrazovavshikhsya produktov pri obluchenii karbogidratov v vodnom rastvore gamma-aktivnym kobal'tom-60 byli razrabotany metody razbavleniya izotopov. Obychnye zhe analiticheskie metody okazalis' nedostatochnymi. Po obluchenii rastvorov S14-sakhar podgotovlennye avtoradiografii posle khromatografii na bumage ukazyvayut na znachitel'noe snizhenie. Ispol'zovanie protsedury obratnogo izotopnogo rastvora, svyazannoj s dobavkoj izvestnykh nositelej i preobrazovaniem oskolkov v derivaty kristallov, byli opredeleny kolichestvennye razmery sleduyushchikh sostavnykh chastej : Mozhno razlichit' d- i i-izomery i proizvesti individual'nuyu otsenku kazhdogo iz nikh. EHtot metod primenyaetsya pri reshenii drugikh analiticheskikh problem v khimii karbogidratov. V doklade daetsya opisanie novogo metoda graficheskogo izobrazheniya i zapisi radio- aktivnosti po liniyam khromogrammy na bumage, chto vozmozhno osushchestvit' pri neznachitel'nykh zatratakh na modifikatsiyu obychnogo schetnogo oborudovaniya. (author)

  10. Urban Everyday Life in the Mirror of Unofficial Oikonymy. Review of the book: Akhmetova, M. V. (2015. Ot A-Ata do Iarska: slovar’ neofitsial’nykh nazvanii naselennykh punktov [From A-At to Yarsk: A Dictionary of Unofficial Settlement Names]. Moscow: FORUM

    Marina V. Golomidova

    2016-11-01

    Full Text Available The paper provides a review of the content and structure of the dictionary of Russian unofficial oikonymy published by Maria Akhmetova. The reviewer points out the author’s ability to make a high-quality presentation of a large number of lexical units: more than 2 200 names and non-standard abbreviations for more than 800 settlements of Russia and neighbouring countries. The material was retrieved from a wide array of sources which include both traditional written texts (toponymic and regional dictionaries, dictionaries of slang, scholarly, journalistic and literary texts and relatively new practices of contemporary Internet communications (blogs, Internet forums, social networks, etc. The reviewer emphasizes the correct and adequate manner of lexicographic processing of unofficial settlement names, as well as the author’s theoretical reasoning on their functional specificity. A particular attention is paid to the ideas articulated in the introduction to the dictionary in which the author attempts to define the status of unofficial oikonyms within the toponymic system of a language, qualifying such names as a particular case of toponymic variability, the latter being the basis of a systemicfunctional approach to the interpretation of unofficial names. The reviewer concludes that Maria Akhmetova’s dictionary enlarges our view of sociolinguistic parameters of the functioning of unofficial oikonyms, which is reflected in an extremely detailed system of labels referring to hitchhikers’ slang, military and naval jargon, obsolete vocabulary, journalistic discourse, nonce words, and others. The dictionary contains rich data that can be used in lexicological, morphological, onomastic, sociolinguistic, anthropological research, but also in studies of urban folklore and urban everyday life.

  11. Obecně závazné vyhlášky obcí v nové judikatuře Ústavního soudu: pohyb zvířat v obci a související otázky

    Müllerová, Hana

    2011-01-01

    Roč. 44, č. 7 (2011), s. 385-403 ISSN 0139-6005 R&D Projects: GA ČR GA407/08/1053 Institutional research plan: CEZ:AV0Z70680506 Keywords : animal regulation * municipal legislation * Animal Welfare Act Subject RIV: AG - Legal Sciences

  12. Aktuální vývoj v otázce definice zločinu agrese ve smyslu čl. 5 Ŕímského statutu Mezinárodní trestního soudu

    Popenková, Monika

    2008-01-01

    Roč. 147, č. 5 (2008), s. 555-585 ISSN 0231-6625 R&D Projects: GA AV ČR KJB700680601 Institutional research plan: CEZ:AV0Z70680506 Keywords : crime of aggression * International Criminal Court * international law Subject RIV: AG - Legal Sciences

  13. Matematické modely chování ocelové obloukové výztuže chodeb při dynamickém zatížení následkem důlních otřesů

    Šňupárek, Richard; Zeman, Vladislav; Horyl, P.; Schellong, L.

    2007-01-01

    Roč. 55, č. 1 (2007), s. 16-20 ISSN 1210-7697 R&D Projects: GA ČBÚ AACBU34-03 Institutional research plan: CEZ:AV0Z30860518 Keywords : rock bursts * dynamic loading * behavior of arched steel support s Subject RIV: DH - Mining , incl. Coal Mining

  14. Oxytocin and Estrogen Receptor β in the Brain: An Overview.

    Acevedo-Rodriguez, Alexandra; Mani, Shaila K; Handa, Robert J

    2015-01-01

    Oxytocin (OT) is a neuropeptide synthesized primarily by neurons of the paraventricular and supraoptic nuclei of the hypothalamus. These neurons have axons that project into the posterior pituitary and release OT into the bloodstream to promote labor and lactation; however, OT neurons also project to other brain areas where it plays a role in numerous brain functions. OT binds to the widely expressed OT receptor (OTR), and, in doing so, it regulates homeostatic processes, social recognition, and fear conditioning. In addition to these functions, OT decreases neuroendocrine stress signaling and anxiety-related and depression-like behaviors. Steroid hormones differentially modulate stress responses and alter OTR expression. In particular, estrogen receptor β activation has been found to both reduce anxiety-related behaviors and increase OT peptide transcription, suggesting a role for OT in this estrogen receptor β-mediated anxiolytic effect. Further research is needed to identify modulators of OT signaling and the pathways utilized and to elucidate molecular mechanisms controlling OT expression to allow better therapeutic manipulations of this system in patient populations.

  15. Organotin Exposure and Vertebrate Reproduction: A Review

    Julia Fernandez Puñal de Araújo

    2018-03-01

    Full Text Available Organotin (OTs compounds are organometallic compounds that are widely used in industry, such as in the manufacture of plastics, pesticides, paints, and others. OTs are released into the environment by anthropogenic actions, leading to contact with aquatic and terrestrial organisms that occur in animal feeding. Although OTs are degraded environmentally, reports have shown the effects of this contamination over the years because it can affect organisms of different trophic levels. OTs act as endocrine-disrupting chemicals (EDCs, which can lead to several abnormalities in organisms. In male animals, OTs decrease the weights of the testis and epididymis and reduce the spermatid count, among other dysfunctions. In female animals, OTs alter the weights of the ovaries and uteri and induce damage to the ovaries. In addition, OTs prevent fetal implantation and reduce mammalian pregnancy rates. OTs cross the placental barrier and accumulate in the placental and fetal tissues. Exposure to OTs in utero leads to the accumulation of lipid droplets in the Sertoli cells and gonocytes of male offspring in addition to inducing early puberty in females. In both genders, this damage is associated with the imbalance of sex hormones and the modulation of the hypothalamic–pituitary–gonadal axis. Here, we report that OTs act as reproductive disruptors in vertebrate studies; among the compounds are tetrabutyltin, tributyltin chloride, tributyltin acetate, triphenyltin chloride, triphenyltin hydroxide, dibutyltin chloride, dibutyltin dichloride, diphenyltin dichloride, monobutyltin, and azocyclotin.

  16. Human ovolution and plasma oxytocin

    Kumaresan, Perianna; Kumaresan, Malathi; Hossini, Mahmood; Arellano, Carolina; Vasicka, Alois

    1983-01-01

    Plasma oxytocin (OT) concentrations were measured by radioimmunoassay (RIA) method without extracting plasma in 11 normal menstruating women. Mean plasma OT level began to increase steadily from the 7th day of the menstrual cycle and this level rose up to 20+-5 μU/ml (Mean+-S.E.) on the 10th day of the cycle. OT level declined to 13+-6 μU/ml on the day of the LH peak and continuously declined for another 2 days - then rose. The OT level was higher during the follicular phase than during the luteal phase. In 1 individual OT measured in 2 cycles a year apart showed the highest level of OT coincided with LH and FSH peak and abruptly declined. When there was the highest level of progesterone, the OT level was measurable 1 out of 11 cycles. From this study, we conclude that OT may have a role in human ovulation either synergistically or alone with other ovulatory mechanisms and ovarian estradiol and progesterone control the secretion of OT and also suggests that OT may play some role in the regulation of the luteolysis and the menstrual cycle in women. (author)

  17. Orthodontic treatment for disabled children: a survey of parents' attitudes and overall satisfaction.

    Abeleira, María Teresa; Pazos, Elisabeth; Ramos, Isabel; Outumuro, Mercedes; Limeres, Jacobo; Seoane-Romero, Juan; Diniz, Marcio; Diz, Pedro

    2014-08-05

    Many patients with disability require orthodontic treatment (OT) to achieve adequate oral function and aesthetic appearance. The cooperation of disabled patients and of their parents is central to the success of OT, as treatment can involve ethical dilemmas. The aim of this study was to analyze the motivation, expectations and overall satisfaction with OT among parents of patients with disabilities. The parents of 60 disabled Spanish children with physical, mental and/or sensory impairment undergoing OT were surveyed on attitudes to OT and level of satisfaction with the outcomes. The survey consisted of 23 questions in 4 sections: attitude and adaptation, benefits, adverse effects, and level of satisfaction after completion of OT. A control group formed of the parents of 60 healthy children undergoing OT at the same institution were also surveyed. Parents of disabled children undergoing OT showed a high level of motivation and they are willing to collaborate in oral hygiene procedures. Adaptation to the removable appliances was poorer in disabled children but adaptation to fixed appliances was excellent. OT can provide a marked improvement in quality of life, social relationships and oral functionality in disabled children. Among parents of disabled children undergoing OT, the perceived level of overall satisfaction was very high and expectations were often exceeded.

  18. Conditioned same-sex partner preference in male rats is facilitated by oxytocin and dopamine: effect on sexually dimorphic brain nuclei.

    Triana-Del Rio, Rodrigo; Tecamachaltzi-Silvarán, Miriam B; Díaz-Estrada, Victor X; Herrera-Covarrubias, Deissy; Corona-Morales, Aleph A; Pfaus, James G; Coria-Avila, Genaro A

    2015-04-15

    Conditioned same-sex partner preference can develop in male rats that undergo cohabitation under the effects of quinpirole (QNP, D2 agonist). Herein, we assessed the development of conditioned same-sex social/sexual preference in males that received either nothing, saline, QNP, oxytocin (OT), or QNP+OT during cohabitation with another male (+) or single-caged (-). This resulted in the following groups: (1) Intact-, (2) Saline+, (3) QNP-, (4) OT-, (5) QNP+, (6) OT+ and (7) QNP/OT+. Cohabitation occurred during 24h in a clean cage with a male partner that bore almond scent on the back as conditioned stimulus. This was repeated every 4 days for a total of three trials. Social and sexual preference were assessed four days after the last conditioning trial in a drug-free test in which experimental males chose between the scented familiar male and a novel sexually receptive female. Results showed that males from groups Intact-, Saline+, QNP- and OT- displayed a clear preference for the female (opposite-sex), whereas groups QNP+, OT+ and QNP/OT+ displayed socio/sexual preference for the male partner (same-sex). In Experiment 2, the brains were processed for Nissl dye and the area size of two sexually dimorphic nuclei (SDN-POA and SON) was compared between groups. Males from groups OT-, OT+ and QNP/OT+ expressed a smaller SDN-POA and groups QNP+ and QNP/OT+ expressed a larger SON. Accordingly, conditioned same-sex social/sexual partner preference can develop during cohabitation under enhanced D2 or OT activity but such preference does not depend on the area size of those sexually dimorphic nuclei. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. Comprehensive, blinded assessment of balance in orthostatic tremor.

    Bhatti, Danish; Thompson, Rebecca; Xia, Yiwen; Hellman, Amy; Schmaderer, Lorene; Suing, Katie; McKune, Jennifer; Penke, Cynthia; Iske, Regan; Roeder, Bobbi Jo; Siu, Ka-Chun; Bertoni, John M; Torres-Russotto, Diego

    2018-02-01

    Orthostatic Tremor (OT) is a movement disorder characterized by a sensation of unsteadiness and tremors in the 13-18 Hz range present upon standing. The pathophysiology of OT is not well understood but there is a relationship between the sensation of instability and leg tremors. Despite the sensation of unsteadiness, OT patients do not fall often and balance in OT has not been formally assessed. We present a prospective blinded study comparing balance assessment in patients with OT versus healthy controls. We prospectively enrolled 34 surface Electromyography (EMG)-confirmed primary OT subjects and 21 healthy controls. Participants underwent evaluations of balance by blinded physical therapists (PT) with standardized, validated, commonly used balance scales and tasks. OT subjects were mostly female (30/34, 88%) and controls were majority males (13/20, 65%). The average age of OT subjects was 68.5 years (range 54-87) and for controls was 69.4 (range 32-86). The average duration of OT symptoms was 18 years. OT subjects did significantly worse on all the balance scales and on most balance tasks including Berg Balance Scale, Functional Gait Assessment, Dynamic Gait Index, Unipedal Stance Test, Functional Reach Test and pull test. Gait speed and five times sit to stand were normal in OT. Common validated balance scales are significantly abnormal in primary OT. Despite the objective finding of impaired balance, OT patients do not commonly have falls. The reported sensation of unsteadiness in this patient population seems to be out of proportion to the number of actual falls. Further studies are needed to determine which components of commonly used balance scales are affected by a sensation of unsteadiness and fear of falling. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. The organizational effects of oxytocin on the central expression of estrogen receptor α and oxytocin in adulthood

    Papademetriou Eros

    2007-09-01

    Full Text Available Abstract Background Previous studies have demonstrated that neonatal manipulation of oxytocin (OT has effects on the expression of estrogen receptor α (ERα and the central production of oxytocin observed in juveniles (at weaning, 21 days of age. The goal of this study was to determine whether the effects of neonatal manipulation of OT last into adulthood, and if the effects differ from those observed during the early postnatal period. On the first day of life, prairie voles (Microtus ochrogaster received one of three doses of OT (High, 3 μg; Med, 0.3 μg; Low, 0.03 μg, an OT antagonist, or isotonic saline. Another group was handled, but not injected. Then as adults, brains were collected, sectioned, and stained for ERα or OT using immunocytochemistry. Results In females, treatment with OT increased the expression of ERα immunoreactivity in the ventral lateral septum (0.03 μg and the ventromedial nucleus of the hypothalamus and central amygdala (0.3 μg. In males, OT antagonist increased ERα expression in the bed nucleus of the stria terminalis. There was no apparent effect of OT on the number of cells producing OT in the paraventricular nucleus of the hypothalamus. Conclusion The current results suggest that neonatal manipulation of OT has long-term organizational effects on the expression of ERα in both males and females. The lack of effect on OT neurons in the paraventricular nucleus suggests that some developmental effects of OT previously observed in weanlings do not persist into adulthood. Developmental effects of OT on ERα patterns were sexually dimorphic, dose-dependent, and site-specific.