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Sample records for karen evans edmond

  1. Health Information in Karen (S’gaw Karen)

    Science.gov (United States)

    ... Thinking of Suicide - S’gaw Karen (Karen) MP3 National Suicide Prevention Lifeline What Is Mental Distress - English ... Karen Chemical Dependency Taskforce of Minnesota Mood Disorders What Is Mental Distress - English PDF What Is ...

  2. Karen Avetovich

    Science.gov (United States)

    Shifman, M.

    2013-06-01

    I was never a student of Karen Avetovich (Karen, as everyone called him behind his back) and never collaborated with him. I've never worked on Reggeistics - the area of high-energy physics that was close to his heart. For an understandable reason - a thirty-year age difference - I couldn't be his close friend. And yet I decided to write a few kind words about Ter-Martirosyan for a reason which will soon become clear...

  3. a Few Lines about Karen

    Science.gov (United States)

    Smorodinskaya, Noemi

    2013-06-01

    Karen had tons of amazing students, and it's unfortunate that they could not contribute to this collection. They would have a lot of marvelous stories to tell, since they spent so many days and nights at Karen's house, enjoying Bella Artemievna's hospitality and kindness. Karen was a difficult person, with many eccentricities, but at the same time he was very kind and forgiving. When people he knew had troubles, he always did whatever he could to help them. I should add, however, that due to the many tragedies he had experienced in his family life, Karen's threshold for what counted as troubles was unusually high, and what others perceived as major problems struck him as the minor complications of everyday life...

  4. Karen Blixen i øst og vest

    DEFF Research Database (Denmark)

    Heede, Dag

    2014-01-01

    Anmeldelser af Ivo Holmqvist (red.): Den främmande förförerskan. Svenska synpunkter på Karen Blixen og Marianne T. Stecher: The Creative Dialectic in Karen Blixen’s Essays. On Gender, Nazi Germany, and Colonial Desire......Anmeldelser af Ivo Holmqvist (red.): Den främmande förförerskan. Svenska synpunkter på Karen Blixen og Marianne T. Stecher: The Creative Dialectic in Karen Blixen’s Essays. On Gender, Nazi Germany, and Colonial Desire...

  5. Word Prosody and Intonation of Sgaw Karen

    Science.gov (United States)

    West, Luke Alexander

    The prosodic, and specifically intonation, systems of Tibeto-Burman languages have received less attention in research than those of other families. This study investigates the word prosody and intonation of Sgaw Karen, a tonal Tibeto-Burman language of eastern Burma, and finds similarities to both closely related Tibeto-Burman languages and the more distant Sinitic languages like Mandarin. Sentences of varying lengths with controlled tonal environments were elicited from a total of 12 participants (5 male). In terms of word prosody, Sgaw Karen does not exhibit word stress cues, but does maintain a prosodic distinction between the more prominent major syllable and the phonologically reduced minor syllable. In terms of intonation, Sgaw Karen patterns like related Pwo Karen in its limited use of post-lexical tone, which is only present at Intonation Phrase (IP) boundaries. Unlike the intonation systems of Pwo Karen and Mandarin, however, Sgaw Karen exhibits downstep across its Accentual Phrases (AP), similarly to phenomena identified in Tibetan and Burmese.

  6. Hydrothermal processes in the Edmond deposits, slow- to intermediate-spreading Central Indian Ridge

    Science.gov (United States)

    Cao, Hong; Sun, Zhilei; Zhai, Shikui; Cao, Zhimin; Jiang, Xuejun; Huang, Wei; Wang, Libo; Zhang, Xilin; He, Yongjun

    2018-04-01

    The Edmond hydrothermal field, located on the Central Indian Ridge (CIR), has a distinct mineralization history owing to its unique magmatic, tectonic, and alteration processes. Here, we report the detailed mineralogical and geochemical characteristics of hydrothermal metal sulfides recovered from this area. Based on the mineralogical investigations, the Edmond hydrothermal deposits comprise of high-temperature Fe-rich massive sulfides, medium-temperature Zn-rich sulfide chimney and low-temperature Ca-rich sulfate mineral assemblages. According to these compositions, three distinctive mineralization stages have been identified: (1) low-temperature consisting largely of anhydrite and pyrite/marcasite; (2) medium-high temperature distinguished by the mineral assemblage of pyrite, sphalerite and chalcopyrite; and (3) low-temperature stage characterized by the mineral assemblage of colloidal pyrite/marcasite, barite, quartz, anglesite. Several lines of evidence suggest that the sulfides were influenced by pervasive low-temperature diffuse flows in this area. The hydrothermal deposits are relatively enriched in Fe (5.99-18.93 wt%), Zn (2.10-10.00 wt%) and Ca (0.02-19.15 wt%), but display low Cu (0.28-0.81 wt%). The mineralogical varieties and low metal content of sulfides in the Edmond hydrothermal field both indicate that extensive water circulation is prevalent below the Edmond hydrothermal field. With regard to trace elements, the contents of Pb, Ba, Sr, As, Au, Ag, and Cd are significantly higher than those in other sediment-starved mid-ocean ridges, which is indicative of contribution from felsic rock sources. Furthermore, the multiphase hydrothermal activity and the pervasive water circulation underneath are speculated to play important roles in element remobilization and enrichment. Our findings deepen our understanding about the complex mineralization process in slow- to intermediate-spreading ridges globally.

  7. 100 maja Veneetsias / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2010-01-01

    Eesti väljapanekust "100 maja / houses" (komissar Ülar Mark, kuraator Karen Jagodin, autorid Kalle Vellevoog, Tiiu Truus, Martin Pedanik, Karen Jagodin) 12. Venezia arhitektuuribiennaalil "Inimesed kohtuvad arhitektuuris" (üldkuraator Kazuyo Sejima). Lisaks 21. sajandi eramutele on ekspositsioonis valik märgilise tähendusega eramuid Eesti Vabariigi ajast aastatel 1918-1940 ja nõukogude ajajärgust

  8. [Dr. Edmond Locard (1877-1966), the Sherlock Holmes of Lyons].

    Science.gov (United States)

    Maze, Michel; Stagnara, Denise; Fischer, Louis-Paul

    2007-01-01

    Doctor Edmond Locard (1877-1966), a French forensic scientist, a disciple of famous Professor Alexandre Lacassagne, created in Lyons, in 1910, the first French laboratory of technical police. During more than fourty years, he used and developed new scientific techniques (fingerprint identification, study of marks and dust...) in order to help the policemen and judges to solve the most horrible crimes.

  9. Karen Armstrong

    NARCIS (Netherlands)

    Jansen, J.J.G.

    2005-01-01

    Karen Armstrong is wereldwijd een van de meest gelezen moderne auteurs over godsdienst. In Nederland is haar populariteit groot. Haar laatste boek, De grote transformatie, is zelfs eerder in het Nederlands verschenen dan in Engeland en Amerika in het Engels. Het succes van haar boeken bewijst dat

  10. Karen Armstrong

    NARCIS (Netherlands)

    Jansen, J.J.G.

    2005-01-01

    Wie is die Karen Armstrong, wier boeken over de hele wereld bestsellers zijn, maar die nergens zo goed verkoopt als in Nederland? Zij is een van de weinige denkers/schrijvers in onze tijd die beseft hoe belangrijk godsdienst in het leven van mensen zijn kan. Dat maakt haar wereldwijd tot een

  11. Karen Strohm Kitchener (1943-2016).

    Science.gov (United States)

    Vasquez, Melba J T

    2016-12-01

    Presents an obituary for Karen Strohm Kitchener, who passed away on April 4, 2016, in a tragic accident near Oahu, Hawaii. One of Karen's major contributions was the development of the Reflective Judgment Model with her colleague, Patricia M. King. This model describes the development of people's ability to make intellectually defensible choices about complex problems that defy right or wrong answers and instead are resolved using multidimensional approaches and reasoned interpretations. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  12. Health and healing: traditional medicine and the Karen experience.

    Science.gov (United States)

    Oleson, Heather E; Chute, Sara; O'Fallon, Ann; Sherwood, Nancy E

    2012-01-01

    To examine the beliefs, attitudes and health-seeking behavior surrounding the use of traditional medicine among the Karen (refugees from Burma). Three focus groups and two key-informant interviews were conducted with the Karen along with observations by researchers. The Karen continue to use elements of their traditional healthcare system after resettling in the U.S. Accessibility and perceived efficacy of treatments influence their health-seeking behavior. The participants discussed beliefs about health and healing, spirituality, and their experience as refugees. Implications for improving the quality of healthcare for the Karen and recommendations for further research are discussed.

  13. Post-arrival health screening in Karen refugees in Australia.

    Science.gov (United States)

    Paxton, Georgia A; Sangster, Katrina J; Maxwell, Ellen L; McBride, Catherine R J; Drewe, Ross H

    2012-01-01

    To document the prevalence of nutritional deficiencies, infectious diseases and susceptibility to vaccine preventable diseases in Karen refugees in Australia. Retrospective audit of pathology results. Community based cohort in Melbourne over the period July 2006-October 2009. 1136 Karen refugee children and adults, representing almost complete local area settlement and 48% of total Victorian Karen humanitarian intake for the time period. Prevalence of positive test results for refugee health screening, with breakdown by age group (Karen refugees have high rates of nutritional deficiencies and infectious diseases and may be susceptible to vaccine preventable diseases. These data support the need for post-arrival health screening and accessible, funded catch-up immunisation.

  14. Keystone characteristics that support cultural resilience in Karen refugee parents

    Science.gov (United States)

    Harper, Susan G.

    2016-12-01

    This participatory action research study used the conceptual framework of social-ecological resilience to explore how Karen (pronounced Ka·rén) refugee parents re-construct cultural resilience in resettlement. The funds of knowledge approach helped to define essential knowledge used by Karen parents within their own community. Framing this study around the concept of resilience situated it within an emancipatory paradigm: refugee parents were actors choosing their own cultural identity and making decisions about what cultural knowledge was important for the science education of their children. Sustainability science with its capacity to absorb indigenous knowledge as legitimate scientific knowledge offered a critical platform for reconciling Karen knowledge with scientific knowledge for science education. Photovoice, participant observation, and semi-structured interviews were used to create visual and written narrative portraits of Karen parents. Narrative analysis revealed that Karen parents had constructed a counter-narrative in Burma and Thailand that enabled them to resist assimilation into the dominant ethnic culture; by contrast, their narrative of life in resettlement in the U.S. focused on the potential for self-determination. Keystone characteristics that contributed to cultural resilience were identified to be the community garden and education as a gateway to a transformed future. Anchored in a cultural tradition of farming, these Karen parents gained perspective and comfort in continuity and the potential of self-determination rooted in the land. Therefore, a cross-cultural learning community for Karen elementary school students that incorporates the Karen language and Karen self-sustaining knowledge of horticulture would be an appropriate venue for building a climate of reciprocity for science learning.

  15. Karen voices on resettlement

    OpenAIRE

    The Karen Women’s Organisation; Sarah Fuller; Eileen Pittaway

    2008-01-01

    With little support and often under threat, members of theKaren Women’s Organisation have conducted research,provided programmes and support, and challenged thewisdom of international NGOs and UNHCR.

  16. Obituary: David Stanley Evans, 1916-2004

    Science.gov (United States)

    Bash, Frank N.

    2005-12-01

    distances. This relation between angular diameters and a V-R color index is called the Barnes-Evans Relation. Tom Barnes gives most of the credit to Evans, but said that David insisted that the authors be listed in alphabetical order. This work was greeted with initial skepticism but it stimulated an enormous amount of interest and has been used to measure distances to 100 Cepheid variable stars in our galaxy. The method gives a distance to one of them, Delta Cephei, that agrees closely with recently measured parallaxes using HST. The Barnes-Evans method yields distances which are accurate to a few percent and is applicable to Cepheids in nearby galaxies. Before coming to Texas, David Evans had never given a large lecture course at a university, and his efforts met with mixed success especially in introductory classes for freshmen facing a "science requirement." David had considerably more success supervising PhD dissertations. He was supervisor for four. He was promoted to the position of Jack S. Josey Centennial Professor of Astronomy in 1984, which is the position he held until his retirement in 1986. He was awarded the Gill Medal of the Astronomical Society of South Africa in 1988. David Evans had a remarkable facility for language, especially English. He was an author of eight books including a 1966 edition of "Teach Yourself Astronomy", which was an introduction to astronomy and an inspiration to a number of currently active astronomers. He also loved history, especially of Southern Hemisphere astronomy but also of the McDonald Observatory. In fact, David continued to be very active after retirement and when he died he had completed a book (with Karen Winget) on the eclipse expedition to Mauritania, which is not yet printed.

  17. Caring for the Karen. A newly arrived refugee group.

    Science.gov (United States)

    Power, David V; Moody, Emily; Trussell, Kristi; O'Fallon, Ann; Chute, Sara; Kyaw, Merdin; Letts, James; Mamo, Blain

    2010-04-01

    Since 2004, Minnesota has seen an influx of refugees from Burma. Many of these newcomers came from the Karen state and spent time in refugee camps in Thailand before resettling in the United States. To better understand the health needs of this population, the authors of this article conducted chart reviews at a St. Paul family medicine clinic that serves a number of Karen refugees and reviewed formal data from the Minnesota Department of Health's Refugee Health Program. Here, they briefly describe this community, the cultural issues that could affect health care providers' ability to care for Karen patients, and the health concerns of these refugees.

  18. [Evans syndrome, pregnancy, and preeclampsia].

    Science.gov (United States)

    Hernández-Salazar, E; Martínez-Abundis, C E; González-Ortiz, C M

    2001-02-01

    Evans' syndrome is an unusual illness of autoimmune etiology, characterized by thrombocytopenia and hemolytic anemia. This is more frequent in females throughout first half of the life and during pregnancy. The present paper describes two pregnant women with Evans syndrome associated to preeclampsia. This report emphasizes how the hematology and coagulation abnormalities of preeclampsia could be added to those abnormalities observed in Evans' syndrome. This association constitutes a severe disease of difficult treatment.

  19. Memories of Karen Avetovich

    Science.gov (United States)

    Nevzorov, Roman

    2013-06-01

    Karen Avetovich Ter-Martirosyan (K.A.) was at once my teacher, scientific adviser, and collaborator. My communication with K.A. enormously influenced my life and career; he helped me to establish the basic values and principles that I try to follow in my everyday life and research activities...

  20. Karen Avetovich Ter-Martirosyan

    Science.gov (United States)

    Shifman, M.

    2013-06-01

    One can say that Karen Avetovich Ter-Martirosyan was one of the stars in the brilliant constellation of theoretical physicists dating back to the golden era of Soviet physics: a disciple of Yakov Frenkel and Lev Landau, he was one of the creators of the theory of (soft) strong interactions at high energies...

  1. Human platelet antigens in Burmese, Karen and north-eastern Thais.

    Science.gov (United States)

    Phuangtham, R; Romphruk, A; Puapairoj, C; Leelayuwat, C; Romphruk, A V

    2017-02-01

    A comparative study of allele frequencies at HPA-1 to -6 and HPA-15 in Burmese and Karen populations as well as at HPA-15 in north-eastern Thais (NET) is presented. Human platelet antigens (HPAs) are clinically important in several immune platelet disorders, including foetal and neonatal alloimmune thrombocytopenia (FNAIT), post-transfusion purpura (PTP) and platelet transfusion refractoriness (PTR). The knowledge of antigen frequencies in a population is essential for the evaluation of patients suffering from immune-mediated platelet disorders. A total of 285 unrelated, healthy Burmese, 242 Karen and 300 NET were recruited to this study. Genotype and allele frequencies of HPA-1 to -6 and HPA-15 were defined using polymerase chain reaction sequence-specific primers (PCR-SSP) RESULTS: No individuals homozygous for HPA-1bb, -2bb, -4bb, -5bb and -6bb were detected. HPA-1a, -2a, -4a, -5a and -6a were present in all samples of Burmese and Karen origin. HPA-1b, -2b, -4b, -5b and -6b were rare in these populations. The frequencies of HPA-3a/-3b were 60·4/39·6% in Burmese and 55·8/44·2% in Karen, respectively. Frequencies of HPA-15a/-15b were 57·2/42·8% in Burmese, 52·5/47·5% in Karen and 49·8/50·2% in NET. The frequencies of HPA genotypes in our study indicates that HPA-1a, -2a, -4a, -5a and -6a are unlikely involved in FNAIT, PTP and PTR in Burmese and Karen populations. However, HPA-1b, -2b, -3a, -3b, -4b, -5b, -6b, -15a and -15b may likely stimulate alloantibodies in these populations. © 2016 British Blood Transfusion Society.

  2. Quirks of dye nomenclature. 1. Evans blue.

    Science.gov (United States)

    Cooksey, C J

    2014-02-01

    The history, origin, identity, chemistry and use of Evans blue dye are described along with the first application to staining by Herbert McLean Evans in 1914. In the 1930s, the dye was marketed under the name, Evans blue dye, which was profoundly more acceptable than the ponderous chemical name.

  3. Lessons Learned: Insights into One Teacher’s Experience Working with Karen Refugee Students in the United States

    Directory of Open Access Journals (Sweden)

    Daniel J. Gilhooly

    2015-01-01

    Full Text Available This study is informed by funds of knowledge and culturally responsive teaching studies that aim to explore and legitimize the cultural knowledge immigrant children bring to their communities and schools. Consequently, this paper specifically addresses issues related to the educational experiences of Karen children and their parents from one American teacher/researcher who has worked with the Karen for the past four years. In aggregate, this paper addresses issues germane to Karen education including; (1 background information on Karen educational experiences prior to resettlement, including a review of their journey from Thailand to the U.S.; (2 important characteristics of Karen culture; (3 Karen names; (4 Sgaw Karen language characteristics; (5 the language divide between parents and children; (6 parental involvement in their children’s schooling; (7 American teacher perceptions of Karen students; (8 issues over grading and, finally; (9 gender issues.

  4. Traditional knowledge on medicinal plant of the Karen in northern Thailand: a comparative study.

    Science.gov (United States)

    Tangjitman, Kornkanok; Wongsawad, Chalobol; Winijchaiyanan, Piyawan; Sukkho, Treetip; Kamwong, Kaweesin; Pongamornkul, Wittaya; Trisonthi, Chusie

    2013-10-28

    We studied traditional medicinal plant knowledge among the Karen in northern Thailand. To compare traditional medicinal knowledge in 14 Karen villages in northern Thailand and determine culturally important medicinal plant species in each Karen village. We interviewed 14 key informants and 438 non-specialist informants about their traditional knowledge of medicinal plants. We tested normality of the data and correlations with distance to the nearest city using Kolmogorov-Smirnov tests and Spearman's rank correlation coefficient. Cluster analysis and cultural importance index (CI) were calculated for the similarity of medicinal plant used and culturally importance medicinal plant species among Karen villages respectively. In total 379 medicinal plant species were used. Number of medicinal plants used positively correlate with distance to the nearest city. Relatively low similarities of medicinal plant species and different CI values for species among the different areas were found. Traditional medicinal plants still play an important role in medicinal practice of the Karen. Local environments, availability of medicinal plant and distance between Karen villages and the nearest city affect the amount of traditional medicinal knowledge in each Karen village. The medicinal plants in this study with high CI values might give some useful leads for further biomedical research. © 2013 Elsevier Ireland Ltd. All rights reserved.

  5. Validation of a brief mental health screener for Karen refugees in primary care.

    Science.gov (United States)

    Brink, Darin R; Shannon, Patricia J; Vinson, Gregory A

    2016-02-01

    Karen refugees from Burma are one of the largest refugee groups currently resettling in the USA. Karen people have endured decades of civil war and human rights violations, leaving them more likely to develop serious mental health disorders. There is a noted lack of brief, culturally validated tools present in primary care settings for detecting posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) in Karen refugees. To create the Karen Mental Health Screener, a five-question screening tool used to identify depression and PTSD and to validate it against a clinical reference standard. This validation study was conducted during a primary care visit. Participants completed a 20-item questionnaire using a 4-point visual aid and the PTSD and MDD portions of the Structured Clinical Interview for DSM Disorders (SCID-CV for DSM-IV) as the reference standard. Both the questionnaire and the relevant sections of the SCID-IV were rigorously translated and administered by trained researchers along with a trained Karen interpreter. Logistic regression models and receiver operating characteristic curve analyses were used to determine a subset of items that could be used to construct a screener to identify Karen patients who were most likely to have PTSD and/or MDD. A final five-question screener was created with very strong performance characteristics. With a clinical cut score of 4, these items displayed very strong performance characteristics with sensitivity = 0.96, specificity = 0.97, positive predicted value = 0.83 and negative predicted value = 0.99. The Karen Mental Health Screener is a valid measure for detecting PTSD and major depression in Karen people from refugee backgrounds presenting in a primary care setting. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  6. Engaging Karen refugee students in science learning through a cross-cultural learning community

    Science.gov (United States)

    Harper, Susan G.

    2017-02-01

    This research explored how Karen (first-generation refugees from Burma) elementary students engaged with the Next Generation Science Standards (NGSS) practice of constructing scientific explanations based on evidence within the context of a cross-cultural learning community. In this action research, the researcher and a Karen parent served as co-teachers for fourth- and fifth-grade Karen and non-Karen students in a science and culture after-school programme in a public elementary school in the rural southeastern United States. Photovoice provided a critical platform for students to create their own cultural discourses for the learning community. The theoretical framework of critical pedagogy of place provided a way for the learning community to decolonise and re-inhabit the learning spaces with knowledge they co-constructed. Narrative analysis of video transcripts of the after-school programme, ethnographic interviews, and focus group discussions from Photovoice revealed a pattern of emerging agency by Karen students in the scientific practice of constructing scientific explanations based on evidence and in Karen language lessons. This evidence suggests that science learning embedded within a cross-cultural learning community can empower refugee students to construct their own hybrid cultural knowledge and leverage that knowledge to engage in a meaningful way with the epistemology of science.

  7. 77 FR 68149 - Karen Paul Holley, M.D.; Decision and Order

    Science.gov (United States)

    2012-11-15

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 12-51] Karen Paul Holley, M.D... revoke the DEA Certificate of Registration (COR), Number BH8988339, of Karen Paul Holley, M.D....D., 74 FR 17528, 174529 (2009); John B. Freitas, D.O., 74 FR 17524, 17525 (2009); Roger A. Rodriguez...

  8. "Can I Ask That?": Perspectives on Perinatal Care After Resettlement Among Karen Refugee Women, Medical Providers, and Community-Based Doulas.

    Science.gov (United States)

    LaMancuso, Kate; Goldman, Roberta E; Nothnagle, Melissa

    2016-04-01

    This study characterized the perspectives of Karen refugee women in Buffalo, NY, their medical providers, and Karen interpreters/doulas on perinatal care for Karen women in resettlement. In-depth qualitative interviews with Karen women (14), Karen doulas/interpreters and key informants (8), and medical providers (6) were informed by the social contextual model and focused on women's questions about and opinions of perinatal care in Buffalo and on providers' experiences caring for Karen patients. Karen women expressed gratitude for and understanding of perinatal care in Buffalo, and providers described Karen patients as agreeable but shy. Karen doulas offered an alternative view that exposed women's many questions and concerns, and described how doula training empowered them as patients' advocates. Low self-efficacy, trauma histories, and cultural expectations may contribute to Karen women's seeming agreeability. Doulas/interpreters possess insider knowledge of women's concerns and facilitate communication between patients and the care team.

  9. Macromolecules and Enzymes: The Geneva Heritage from Kurt H. Meyer and Edmond H. Fischer.

    Science.gov (United States)

    Fischer, Edmond H; Piguet, Alfred

    2009-12-01

    On the 26th May 2009, Edmond Fischer, winner with Ed Krebs of the Nobel prize in physiology or medicine in 1992, and his colleague at the time of his research activities at the Ecole de chimie of the University of Geneva, Alfred Piguet, met with Andreas Hauser, Claude Piguet and Howard Riezman of the Section de chimie et biochimie of the University of Geneva to talk about how they became scientists under the impetus of Kurt H. Meyer and what became of them thereafter.

  10. Entrevue guidée avec Karen Messing

    Directory of Open Access Journals (Sweden)

    Ana-Maria Seifert

    2009-02-01

    Full Text Available Karen Messing nous a accordé une entrevue pour la rubrique des Défricheurs de PISTES de la revue. Dans son cas nous devons plutôt parler d’une défricheuse de pistes. En effet, tout au long de sa vie professionnelle elle s’est intéressée aux particularités reliées à la question du genre dans le travail et plus particulièrement au travail des femmes et à ses conséquences sur leur santé. Elle était professeure à l’Université du Québec à Montréal, elle vient tout juste de prendre sa retraite « officielle ». Elle est détentrice d’un doctorat en biologie et elle s’est graduellement intéressée à la question de l’environnement de travail et à ses effets sur la santé des personnes. Au début des années 90, elle est allée se perfectionner en ergonomie afin de se doter d’outils d’analyse du travail. Ses recherches ont porté sur plusieurs métiers (préposés aux bénéficiaires, préposés au nettoyage, caissières, etc.. Karen Messing a publié plusieurs livres et articles scientifiques sur la question qui sont importants. Nous vous invitons à la connaître un peu mieux.Karen Messing granted us an interview for the magazine’s Défricheurs de PISTES section. In her case, she is a groundbreaker. In fact, throughout her professional life, she has been interested in the specific issues related to the subject of gender in work, and particularly to women’s work and its impacts on their health. She was a professor at the Université du Québec à Montréal, and has just begun her “official” retirement. She has a doctorate in biology and gradually became interested in the subject of the work environment and its effects on people’s health. In the early 1990s, she refined her skills in ergonomics in order to have the necessary work analysis tools. Her research has investigated several professions (orderlies, cleaning workers, cashiers, etc.. Karen Messing has published several important scientific books and

  11. Engaging Karen Refugee Students in Science Learning through a Cross-Cultural Learning Community

    Science.gov (United States)

    Harper, Susan G.

    2017-01-01

    This research explored how Karen (first-generation refugees from Burma) elementary students engaged with the Next Generation Science Standards (NGSS) practice of constructing scientific explanations based on evidence within the context of a cross-cultural learning community. In this action research, the researcher and a Karen parent served as…

  12. Karen W. Tice, Tales of Wayward Girls and Immoral Women

    OpenAIRE

    Niget, David

    2009-01-01

    Tales of Wayward Girls and Immoral Women : Case Records and the Professionalization of Social Work Karen W. Tice Chicago, University of Illinois Press, 1998, 272 p. ISBN: 0252023978 Cet ouvrage n’est ni une étude de socio-histoire des professions sociales, ni une monographie des populations vulnérables prises en charge par les agences sociales qui se multiplient au début du XXe siècle en Amérique du Nord. Karen Tice, enseignante en sciences de l’éducation et en études féministes, a adopté un...

  13. Assessment of HNA alloimmunisation risk in Northeastern Thais, Burmese and Karen.

    Science.gov (United States)

    Simtong, P; Puapairoj, C; Leelayuwat, C; Santoso, S; Romphruk, A V

    2018-02-01

    This study aimed to determine human neutrophil antigen (HNA) frequency, estimate possible HNA incompatibilities and predict the risk of HNA alloimmunisation in the Northeastern Thai, Burmese and Karen populations. Alloantibodies against HNA are implicated in a number of clinical conditions, including immune-mediated neutropenia and transfusion reactions. A total of 400 unrelated healthy Thais, 261 Burmese and 249 Karen was included in this study. DNA samples were typed for HNA-1, -3, -4 and -5 systems using polymerase chain reactions with sequence-specific primers (PCR-SSP). In this cohort, HNA-1a was more prevalent than HNA-1b. Accordingly, the possible risk of HNA-1a alloimmunisation against HNA-1a is lower than HNA-1b (0·0802-0·1351 vs 0·2293-0·2497). This is in contrast to the situation reported in Caucasian and African populations. The predicted risk of HNA-3 incompatibility in Thais, Burmese and Karen were 28·09%, 30·66% and 22·77%, respectively. The possible risks of HNA-3a alloimmunisation were 0·0493 in Thais, 0·0608 in Burmese and 0·0196 in Karen, respectively. No individuals were found to be homozygous for HNA-4bb. The probability of developing alloantibodies against HNA-4a was low in these populations and every population in Asia. In contrast, the overall frequency of HNA-5bb homozygous individuals was high in this study, peaking at 0·192. This is the first study that reported the allele frequencies of HNA-1, -3, -4, and -5 in a large sample of healthy unrelated individuals from ethnic Thais, Burmese and Karen. Our results indicated the high possible risk of HNA-1, -3 and -5 alloimmunisation in these populations. © 2017 British Blood Transfusion Society.

  14. Ethnomedicinal knowledge among Karens of Andaman & Nicobar Islands, India.

    Science.gov (United States)

    Chander, M Punnam; Kartick, C; Vijayachari, P

    2015-03-13

    This study documents the use of medicinal plants by Karens of Middle Andaman, of the Andaman and Nicobar Islands. In spite of the availability of modern medicines, Karens preferred herbal remedies provided by the Traditional Knowledge Practitioners (TKPs), who served as their healers. Hence, the aim of this study was to collect information from TKPs and determine the significance of plants utilized for medicinal purposes. The informant consensus factor (ICF) in relation to medicinal plants used was also estimated and analysed. Field research was conducted in three villages of Middle Andaman, inhabited by Karens, during October 2010 - February 2013. TKPs were interviewed with a questionnaire-guided ethno-medical survey protocol. The data obtained were analysed using the informant consensus factor (ICF) and use value (UV). Voucher specimens of all the cited plants were deposited at Regional Medical Research Centre (ICMR), Port Blair. Use of 78 medicinal plant species belonging to 71 genera encompassing 48 families was recorded during the survey. These plants were used to treat 38 different ailments, and divided into ten categories of use. The highest ICF value (0.79) was observed for infections and infestations. The Zingiberaceae and Fabaceae families exhibited the highest number of species, and the plants with the highest use values were Typha angustifolia L., Millingtonia hortensis L. f. and Piper betle L. The most common growth form observed were herbs (42%). Among the several plant parts used, leaves were mostly preferred for preparation of medicines. Water was the main excipient used for mixing the herbs. This study documents the use of medicinal plants by Karens of the Andaman and Nicobar Islands. Phytochemical and pharmacological aspects of these plants need to be studied, to confirm their efficacy and safety, and determine their potential use in modern medicine. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  15. Pregnancy and Evans´ syndrome: case report

    Directory of Open Access Journals (Sweden)

    Santiago Artucio

    2015-12-01

    Full Text Available Evans´ syndrome is the coexistence of autoimmune thrombocytopenia with autoimmune hemolytic anemia. It is rarely found during the course of a pregnancy. This makes treatment options more difficult, since some therapeutic drugs are teratogenic. The effects of Evans´ syndrome in the fetus and newborn are unknown given the low number of reported cases. We report the case of a patient with preconceptional diagnosis of Evans´ syndrome, who develops a hemolytic crisis during the course of a pregnancy, and diagnosis of intrauterine growth restriction (IUGR, treated at Clínica Ginecotocológica “A” at the Pereira Rossell Hospital Center, in Montevideo, Uruguay. Treatment options and evolution are analyzed, as well as previous reports.

  16. The Role of Digital Literacy Practices on Refugee Resettlement: The Case of Three Karen Brothers

    Science.gov (United States)

    Gilhooly, Daniel; Lee, Eunbae

    2014-01-01

    This study explores the social and cultural uses of digital literacies by adolescent immigrants to cope with their new lives in the United States. This case study focuses on three adolescent ethnic Karen brothers. Two years of participant observations in their home and Karen community, accompanied by formal and informal interviews, served as the…

  17. Use of the Edmonds-Reilly Model to model energy-related greenhouse gas emissions

    International Nuclear Information System (INIS)

    Barns, D.W.; Edmonds, J.A.; Reillyn, J.M.

    1992-01-01

    The purpose of this paper is to document the results of our application of the Edmonds-Reilly Model (ERM) using several scenarios provided for an Organization for Economic Cooperation and Development (OECD) project comparing global models. Because the output of this exercise is data-rich, most of this exposition is in graphical form, with the narrative serving mainly as a roadmap for moving from one highlight to the next. The first two sections of the paper briefly describe the model and some of the special modifications made for this effort. The case-by-case discussion is contained in Section IV, followed by a summary of the potential pitfalls involved in attempting to assess the cost of emissions reduction from the model data

  18. Awards for Lyn Evans and Philippe Lebrun

    CERN Multimedia

    2007-01-01

    Lyn Evans has received the American Physical Society’s Robert R. Wilson Prize, while Philippe Lebrun has been awarded an honorary doctorate by the Wrocław University of Technology in Poland. Lyn Evans in front of an LHC dipole magnet. Philippe Lebrun (centre) with the Dean of the Faculty of mechanical and power engineering of the Wrocław University during the ceremony (courtesy of Laurent Tavian).Numerous honours are going to the LHC and those behind it even before this exceptional machine begins operation. The LHC Project Leader, Lyn Evans, has recently been awarded the "Robert R. Wilson Prize for Achievement in the Physics of Particle Accelerators" by the American Physical Society (APS). According to the citation, the prize was awarded "for a sustained career of technical innovation and leadership in the SPS proton-antiproton collider, culminating in the construction and commissioning of the LHC&am...

  19. Síndrome de Evans en lactantes

    OpenAIRE

    Flores-Montes, Olivia Alejandra; Escobar-Orduño, Martha Cecilia; Lozano-Garcidueñas, Mónica; Valle-Leal, Jaime Guadalupe

    2017-01-01

    Introducción: El síndrome de Evans se caracteriza por la disminución de, al menos, dos líneas celulares en ausencia de otros diagnósticos. Anteriormente, se definía como el desarrollo simultáneo o secuencial de trombocitopenia inmune primaria y anemia hemolítica autoinmune sin etiología específica. Se ha reportado una incidencia del 37% y una mortalidad del 10% de este síndrome. Casos clínicos: Se presenta la información clínica y la evolución del síndrome de Evans en dos pacientes lactant...

  20. Sacred Networks and Struggles among the Karen Baptists across the Thailand-Burma Border Réseaux sacrés et conflits parmi les Baptistes karen de part et d’autre de la frontière birmano-thaïlandaise

    Directory of Open Access Journals (Sweden)

    Alexander Horstmann

    2012-10-01

    Full Text Available In this article, I provide a case study of a moving border between Thailand and Burma. Emphasizing the agency of people who become refugees, the article is concerned to point out the important role of religious networks in providing humanitarian assistance, shelter and mobility to stateless Karen refugees. I argue that Christian and Buddhist literate networks- realigned in political exile, develop competing visions of a Karen “homeland.” Arguing that membership in the network is crucial for survival, the article follows the social organization and religious practices in Baptist networks. I examine how the Baptist church network in close partnership with the Karen National Union is able or not able to mobilize refugees for proselytization. Karen refugee leaders and KNU-pastors find analogies in the bible to find an explanation to the suffering of the Karen civil population in the war. The article is interested in the nexus and overlap of humanitarian ideology, Christianity and nationalism in the transitional space between Thailand and Burma. Providing case-studies of individual refugees, the article gives ethnographic sketches from the refugee camp, the countryside and humanitarian assistance to the internally displaced.Cet article est une étude de cas d’une frontière mouvante entre la Thaïlande et la Birmanie. Insistant sur l’agency (action de personnes devenues des réfugiés, l’article souligne le rôle important des réseaux religieux qui apportent une assistance humanitaire, des abris et de la mobilité à des réfugiés karen dépourvus d’État. Je soutiens que les réseaux intellectuels chrétiens et bouddhistes, recomposés dans l’exil, développent des visions concurrentes d’une « mère-patrie » karen. Soutenant que la participation au réseau est cruciale pour la survie, l’article développe plus particulièrement l’organisation sociale et les pratiques religieuses en vigueur dans les réseaux baptistes. J

  1. Assessment of the Psychosocial Development of Children Attending Nursery Schools in Karen Refugee Camps in Thailand

    Science.gov (United States)

    Tanaka, Akiko

    2013-01-01

    The Karen, an ethnic minority group in Burma, have experienced a prolonged state of exile in refugee camps in neighboring Thailand because of ethnic conflict in their home country. Nursery schools in the three largest Karen refugee camps aim to promote the psychosocial development of young children by providing a child-centered, creative,…

  2. The Karen instruments for measuring quality of nursing care: construct validity and internal consistency.

    Science.gov (United States)

    Lindgren, Margareta; Andersson, Inger S

    2011-06-01

    Valid and reliable instruments for measuring the quality of care are needed for evaluation and improvement of nursing care. Previously developed and evaluated instruments, the Karen-patient and the Karen-personnel based on Donabedian's Structure-Process-Outcome triad (S-P-O triad) had promising content validity, discriminative power and internal consistency. The objective of this study was to further develop the instruments with regard to construct validity and internal consistency. This prospective study was carried out in medical and surgical wards at a hospital in Sweden. A total of 95 patients and 120 personnel were included. The instruments were tested for construct validity by performing factor analyses in two steps and for internal consistency using Cronbach's alpha coefficient. The first confirmatory factor analyses, with a pre-determined three-factor solution did not load well according to the S-P-O triad, but the second exploratory factor analysis with a six-factor solution appeared to be more coherent and the distribution of variables seemed to be logical. The reliability, i.e. internal consistency, was good in both factor analyses. The Karen-patient and the Karen-personnel instruments have achieved acceptable levels of construct validity. The internal consistency of the instruments is good. This indicates that the instruments may be suitable to use in clinical practice for measuring the quality of nursing care.

  3. EVANS SYNDROME IN A 10 YEAR OLD GIRL

    Directory of Open Access Journals (Sweden)

    A. Ariputra

    2015-10-01

    Full Text Available Evans syndrome is a coexistence of simultaneous or sequential positive direct Coombs test in conjunctionwith  immune-mediated  thrombocytopenia with no known underlying etiology. The  clinical  course  ischronic and relapsing, and the therapy is generally progressive. Recurrences of thrombocytopenia, anemiaand neutropenia are common, as well as episodes of hemorrhage and serious infections. Noncrossreactingautoantibodies are directed against red cells, platelets, and neutrophils antigens. Evans syndrome isa rare condition, no predilection is known and its exact prevalent is unknown. We report a case of Evanssyndrome in 10 years old girl with severe anemia and thrombocytopenia. Patient came with clinicalsymptoms of severe anemia. The laboratory evaluation showed severe anemia, increased reticulocytecount, anisopoikilocytosis erythrocyte, increased unconjugated bilirubin, positive direct Coombs testand thrombocytopenia. Patient was then managed with high doses of corticosteroids and showed goodresponse from both clinical and laboratory evaluations. [MEDICINA 2015;46:61-66].Sindrom Evans adalah suatu penyakit yang ditandai dengan adanya hasil positif pada direct Coombstest dan trombositopenia yang diperantarai  imun secara simultan atau sekuensial tanpa penyebabyang  jelas. Perjalanan klinis umumnya bersifat kronis, sering mengalami relaps dan memerlukanterapi yang progresif. Kejadian trombositopenia, anemia, neutropenia, perdarahan dan episode infeksiberat berulang umum terjadi. Pada sindrom ini, terjadi reaksi autoantibodi spesifik terhadap antigensel darah merah, trombosit dan juga neutrofil. Sindrom Evans merupakan kasus yang jarang ditemukandan dengan predileksi serta prevalensi yang belum banyak diketahui. Kami melaporkan satu kasusSindrom Evans pada anak perempuan usia 10 tahun.  Pasien dengan gejala klinis anemia berat dan padapemeriksaan laboratorium menunjukkan suatu anemia berat, peningkatan hitung retikulosit, gambaraneritrosit

  4. Nostalgia Arhitektuurimuuseumis : kuldsed kuuekümnendad / Karen Jagodin ; interv. Ellu Maar

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Näitusest "Kuuekümnendad. Eesti moodne arhitektuur" ja sisearhitektide Väino Tamme ning Vello Asi loomingu näitusest Eesti Arhitektuurimuuseumis. Kuraatorid Karin Hallas-Murula ja Karen Jagodin. Eesti 1960. aastate sisearhitektuurist

  5. Astronaut Ronald Evans photographed during transearth coast EVA

    Science.gov (United States)

    1972-01-01

    Astronaut Ronald E. Evans is photographed performing extravehicular activity (EVA) during the Apollo 17 spacecraft's transearth coast. During his EVA Command Module pilot Evans retrieved film cassettes from the Lunar Sounder, Mapping Camera, and Panoramic Camera. The total time for the transearth EVA was one hour seven minutes 19 seconds, starting at ground elapsed time of 257:25 (2:28 p.m.) amd ending at ground elapsed time of 258:42 (3:35 p.m.) on Sunday, December 17, 1972.

  6. The Case of Three Karen Refugee Women and Their Children: Literacy Practices in a Family Literacy Context

    Science.gov (United States)

    Quadros, Sabrina; Sarroub, Loukia K.

    2016-01-01

    The lack of research about the Karen, one of 135 ethnic groups from Myanmar limits literacy educators charged with educating this refugee population in public schools. In this case study the authors explore the literacy practices of Karen families when at school and in their homes and within an ESL family literacy program. The case of these…

  7. Predicting prediabetes in a rural community: a survey among the Karen ethnic community, Thasongyang, Thailand.

    Science.gov (United States)

    Lorga, Thaworn; Aung, Myo Nyein; Naunboonruang, Prissana; Thinuan, Payom; Praipaksin, Nara; Deesakul, Tida; Inwan, Utumporn; Yingtaweesak, Tawatchai; Manokulanan, Pratumpan; Suangkaew, Srisomporn; Payaprom, Apiradee

    2012-01-01

    Diabetes is a growing epidemic in both urban and rural communities worldwide. We aimed to survey fasting plasma glucose (FPG) status and awareness of diabetes in the rural Karen ethnic community. We investigated the predictors of impaired fasting plasma glucose (IFG) status, which would be easily applicable for prevention of diabetes in a rural community. This was a community-based cross-sectional study conducted at Thasongyang, the most north-western district in Thailand. A total of 299 Karen ethnic rural residents were included in the study. FPG, body mass index, and waist circumference were prospectively measured. We assessed the awareness of diabetes and lifestyle-related health behavior with closed questionnaires in a rural community setting. On screening for FPG, 16.72% of the Karen ethnic residents had hyperglycemia: 3.68% in the diabetic range and 13.04% in the prediabetic range respectively. After adjustment for age, sex, and BMI, waist circumference (adjusted odds ratio [aOR] 3.5, 95% confidence interval [CI] 1.29-9.57), and having a diabetic blood relative (aOR 4.6, CI 1.81-11.71) are significant predictors of IFG status. It is necessary to promote awareness of diabetes among the Karen ethnic community. Application of simple evidence-based predictors of the prediabetic state may lead to timely and effective prevention of diabetes in rural settings.

  8. HLA alleles and haplotypes in Burmese (Myanmarese) and Karen in Thailand.

    Science.gov (United States)

    Kongmaroeng, C; Romphruk, A; Puapairoj, C; Leelayuwat, C; Kulski, J K; Inoko, H; Dunn, D S; Romphruk, A V

    2015-09-01

    This is the first report on human leukocyte antigen (HLA) allele and haplotype frequencies at three class I loci and two class II loci in unrelated healthy individuals from two ethnic groups, 170 Burmese and 200 Karen, originally from Burma (Myanmar), but sampled while residing in Thailand. Overall, the HLA allele and haplotype frequencies detected by polymerase chain reaction sequence-specific primer (PCR-SSP) at five loci (A, B, C, DRB1 and DRQB1) at low resolution showed distinct differences between the Burmese and Karen. In Burmese, five HLA-B*15 haplotypes with different HLA-A and HLA-DR/DQ combinations were detected with three of these not previously reported in other Asian populations. The data are important in the fields of anthropology, transplantation and disease-association studies. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. Astronaut Ronald Evans is suited up for EVA training

    Science.gov (United States)

    1972-01-01

    Astronaut Ronald E. Evans, command module pilot of the Apollo 17 lunar landing mission, is assisted by technicians in suiting up for extravehicular activity (EVA) training in a water tank in bldg 5 at the Manned Spacecraft Center (49970); Evans participates in EVA training in a water tank in bldg 5 at the Manned Spacecraft Center. The structure in the picture simulates the Scientific Instrument Module (SIM) bay of the Apollo 17 Service Module (49971).

  10. War trauma and torture experiences reported during public health screening of newly resettled Karen refugees: a qualitative study.

    Science.gov (United States)

    Cook, Tonya L; Shannon, Patricia J; Vinson, Gregory A; Letts, James P; Dwee, Ehtaw

    2015-04-08

    Karen refugees have suffered traumatic experiences that affect their physical and mental health in resettlement. The United States Centers for Disease Control and Prevention recommends assessing traumatic histories and mental health symptoms during initial public health screening. This article reports the traumatic experiences that Karen refugees were able to describe during a short screening and contributes knowledge to existing human rights documentation systems. Four semi-structured and open-ended items asked about lifetime experiences of war trauma and torture. Interviews were completed with adult, Karen refugees during their initial public health screening. Experiences of war trauma and torture were coded using the extensive Human Rights Information and Documentation (HURIDOCS) Micro-thesauri coding system. Additional codes were created to describe experiences not captured by existing codes. Over 85% of 179 Karen people interviewed experienced life-threatening war trauma. All participants who reported war trauma or torture stories were able to describe at least one event. New war trauma codes proposed include: widespread community fear, systematic destruction/burning of house or village, exposure to dead bodies, orphaned in the context of war, injury caused by a landmine, fear of Thai police or deportation from Thailand, and harm or killings in the context of war. New torture codes include: forced portering; forced to be a human landmine sweep; forced to be a soldier, including child soldier; forced contact with a dead body; and removal of the eyes. Karen refugees were able to report traumatic experiences in the context of a brief health screening. The findings confirm existing reports of human rights violations against Karen people and suggest that additional codes be added to the HURIDOCS Micro-thesauri system that is used by torture treatment centers. Understanding the nature of traumatic experiences of this group is important for health providers working

  11. Review: Michael Crandall & Karen E. Fisher (Eds) Digital Inclusion: Measuring the Impact of Information and Community Technology

    DEFF Research Database (Denmark)

    Pors, Niels Ole

    2010-01-01

    Review: Michael Crandall & Karen E. Fisher (Eds) Digital Inclusion: Measuring the Impact of Information and Community Technology. Medford. Information Today. ASIS&T Monographs, 2009. 185 pages. $ 59.50. ISBN 978-1-57387-373-4......Review: Michael Crandall & Karen E. Fisher (Eds) Digital Inclusion: Measuring the Impact of Information and Community Technology. Medford. Information Today. ASIS&T Monographs, 2009. 185 pages. $ 59.50. ISBN 978-1-57387-373-4...

  12. Predicting prediabetes in a rural community: a survey among the Karen ethnic community, Thasongyang, Thailand

    Directory of Open Access Journals (Sweden)

    Lorga T

    2012-03-01

    Full Text Available Thaworn Lorga1, Myo Nyein Aung1,2, Prissana Naunboonruang1, Payom Thinuan1, Nara Praipaksin3, Tida Deesakul3, Utumporn Inwan3, Tawatchai Yingtaweesak4, Pratumpan Manokulanan1, Srisomporn Suangkaew1, Apiradee Payaprom41Boromarajonani College of Nursing Nakhon Lampang (BCNLP, Lampang, Thailand; 2Department of Public Health, Graduate School of Medicine, Juntendo University, Tokyo, Japan; 3Baan Rekati Health Station, Thasongyang, Tak, Thailand; 4Thasongyang Hospital, Thasongyang, Tak, ThailandBackground: Diabetes is a growing epidemic in both urban and rural communities worldwide.Aim: We aimed to survey fasting plasma glucose (FPG status and awareness of diabetes in the rural Karen ethnic community. We investigated the predictors of impaired fasting plasma glucose (IFG status, which would be easily applicable for prevention of diabetes in a rural community.Materials and methods: This was a community-based cross-sectional study conducted at Thasongyang, the most north-western district in Thailand. A total of 299 Karen ethnic rural residents were included in the study. FPG, body mass index, and waist circumference were prospectively measured. We assessed the awareness of diabetes and lifestyle-related health behavior with closed questionnaires in a rural community setting.Results: On screening for FPG, 16.72% of the Karen ethnic residents had hyperglycemia: 3.68% in the diabetic range and 13.04% in the prediabetic range respectively. After adjustment for age, sex, and BMI, waist circumference (adjusted odds ratio [aOR] 3.5, 95% confidence interval [CI] 1.29–9.57, and having a diabetic blood relative (aOR 4.6, CI 1.81–11.71 are significant predictors of IFG status.Conclusion: It is necessary to promote awareness of diabetes among the Karen ethnic community. Application of simple evidence-based predictors of the prediabetic state may lead to timely and effective prevention of diabetes in rural settings.Keywords: diabetes, prediabetes, fasting plasma

  13. A strange case of Evans syndrome

    Directory of Open Access Journals (Sweden)

    Manuel Monti

    2013-12-01

    Full Text Available Evans syndrome is a rare autoimmune disease presenting hemolytic anemia, thrombocytopenia and/or neutropenia. It may be associated with other autoimmune or lymphoproliferative diseases. It can have an extremely serious disease course and, in rare cases, this can even be life-threatening. First-line treatment consists of steroids and/or immunoglobulin. Further therapy with rituximab, vincristine, cyclophosphamide and other immunosuppressive drugs can be considered in unresponsive patients. We report a case of Evans syndrome in a 54-year old woman admitted to the Emergency Department (ED for asthenia. Etiopathogenic, clinical, therapeutic and evolutive aspects are discussed. In contrast to many cases described in the literature, our patient had a satisfactory response to corticoids. We also discuss how to make a specific diagnosis, even in a suburban ED with limited resources, in order to admit patients to the appropriate hospital department and allow the correct therapy to be started as early as possible.

  14. Estimated ventricle size using Evans index: reference values from a population-based sample.

    Science.gov (United States)

    Jaraj, D; Rabiei, K; Marlow, T; Jensen, C; Skoog, I; Wikkelsø, C

    2017-03-01

    Evans index is an estimate of ventricular size used in the diagnosis of idiopathic normal-pressure hydrocephalus (iNPH). Values >0.3 are considered pathological and are required by guidelines for the diagnosis of iNPH. However, there are no previous epidemiological studies on Evans index, and normal values in adults are thus not precisely known. We examined a representative sample to obtain reference values and descriptive data on Evans index. A population-based sample (n = 1235) of men and women aged ≥70 years was examined. The sample comprised people living in private households and residential care, systematically selected from the Swedish population register. Neuropsychiatric examinations, including head computed tomography, were performed between 1986 and 2000. Evans index ranged from 0.11 to 0.46. The mean value in the total sample was 0.28 (SD, 0.04) and 20.6% (n = 255) had values >0.3. Among men aged ≥80 years, the mean value of Evans index was 0.3 (SD, 0.03). Individuals with dementia had a mean value of Evans index of 0.31 (SD, 0.05) and those with radiological signs of iNPH had a mean value of 0.36 (SD, 0.04). A substantial number of subjects had ventricular enlargement according to current criteria. Clinicians and researchers need to be aware of the range of values among older individuals. © 2017 EAN.

  15. Drainage effects on the transient, near-surface hydrologic response of a steep hillslope to rainfall: Implications for slope stability, Edmonds, Washington, USA

    Science.gov (United States)

    Biavati, G.; Godt, J.W.; McKenna, J.P.

    2006-01-01

    Shallow landslides on steep (>25??) hillsides along Puget Sound have resulted in occasional loss of life and costly damage to property during intense or prolonged rainfall. As part of a larger project to assess landslide hazards in the Seattle area, the U.S. Geological Survey instrumented two coastal bluff sites in 2001 to observe the subsurface hydrologic response to rainfall. The instrumentation at one of these sites, near Edmonds, Washington, consists of two rain gauges, two water-content probes that measure volumetric water content at eight depths between 0.2 and 2.0 m, and two tensiometer nests that measure soil-water suction at six depths ranging from 0.2 to 1.5m. Measurements from these instruments are used to test one- and two-dimensional numerical models of infiltration and groundwater flow. Capillary-rise tests, performed in the laboratory on soil sample from the Edmonds site, are used to define the soil hydraulic properties for the wetting process. The field observations of water content and suction show an apparent effect of porosity variation with depth on the hydraulic response to rainfall. Using a range of physical properties consistent with our laboratory and field measurements, we perform sensitivity analyses to investigate the effects of variation in physical and hydraulic properties of the soil on rainfall infiltration, pore-pressure response, and, hence, slope stability. For a two-layer-system in which the hydraulic conductivity of the upper layer is at least 10 times greater than the conductivity of the lower layer, and the infiltration rate is greater than the conductivity of the lower layer, a perched water table forms above the layer boundary potentially destabilizing the upper layer of soil. Two-dimensional modeling results indicate that the addition of a simple trench drain to the same two-layer slope has differing effects on the hydraulic response depending on the initial pressure head conditions. For slope-parallel flow conditions

  16. Drainage effects on the transient, near-surface hydrologic response of a steep hillslope to rainfall: implications for slope stability, Edmonds, Washington, USA

    Directory of Open Access Journals (Sweden)

    G. Biavati

    2006-01-01

    Full Text Available Shallow landslides on steep (>25° hillsides along Puget Sound have resulted in occasional loss of life and costly damage to property during intense or prolonged rainfall. As part of a larger project to assess landslide hazards in the Seattle area, the U.S. Geological Survey instrumented two coastal bluff sites in 2001 to observe the subsurface hydrologic response to rainfall. The instrumentation at one of these sites, near Edmonds, Washington, consists of two rain gauges, two water-content probes that measure volumetric water content at eight depths between 0.2 and 2.0 m, and two tensiometer nests that measure soil-water suction at six depths ranging from 0.2 to 1.5 m. Measurements from these instruments are used to test one- and two-dimensional numerical models of infiltration and groundwater flow. Capillary-rise tests, performed in the laboratory on soil sample from the Edmonds site, are used to define the soil hydraulic properties for the wetting process. The field observations of water content and suction show an apparent effect of porosity variation with depth on the hydraulic response to rainfall. Using a range of physical properties consistent with our laboratory and field measurements, we perform sensitivity analyses to investigate the effects of variation in physical and hydraulic properties of the soil on rainfall infiltration, pore-pressure response, and, hence, slope stability. For a two-layer-system in which the hydraulic conductivity of the upper layer is at least 10 times greater than the conductivity of the lower layer, and the infiltration rate is greater than the conductivity of the lower layer, a perched water table forms above the layer boundary potentially destabilizing the upper layer of soil. Two-dimensional modeling results indicate that the addition of a simple trench drain to the same two-layer slope has differing effects on the hydraulic response depending on the initial pressure head conditions. For slope

  17. The meaning and value of traditional occupational practice: a Karen woman's story of weaving in the United States.

    Science.gov (United States)

    Smith, Yda J; Stephenson, Stephanie; Gibson-Satterthwaite, Michelle

    2013-01-01

    This case study sought to understand the meaning of restoring traditional weaving as an occupation among Karen women from Burma who now live in an urban city in the United States and to examine the impact of weaving on their daily lives in terms of identity, empowerment, social support, and opportunities for entrepreneurship. The story of one Karen woman, Paw Law Eh, is described. Her story exemplifies the negative consequences of restricted access to familiar and meaningful daily activities, or "occupations", the relationship between occupation and self-identity, how participation in valued occupations can enhance social networks, and the restorative effects that are possible when engagement in meaningful occupations are maintained or restored. Her story demonstrates that occupational therapists have the skills and opportunity to contribute significantly to the well-being of Karen women by supporting the restoration of the occupation of weaving.

  18. Experience with Evans syndrome in an academic referral center

    Directory of Open Access Journals (Sweden)

    José Carlos Jaime-Pérez

    2015-08-01

    Full Text Available OBJECTIVE: To document the experience of one referral service with patients diagnosed with Evans syndrome, the treatment and response and to briefly review current treatment strategies and results.METHODS: Patients enrolled in this study fulfilled criteria for Evans syndrome. Data were retrieved from the clinical files and electronic databases of the Department of Hematology, Hospital Universitario "Dr. José Eleuterio González". Treatment modalities and response and the use of additional therapies were evaluated. The literature was reviewed in the context of the clinical course of the studied patients.RESULTS: Six patients were diagnosed with Evans syndrome in the study period. Patient 1 was treated with steroids, relapsed twice and was again treated with steroids. Patient 2 treated initially with steroids plus intravenous immunoglobulin was subsequently lost to follow-up. A good response was achieved in Patients 3 and 4, who were treated with steroids plus rituximab; patient 4 also received danazol as a second-line therapy. However both relapsed and subsequently underwent splenectomy at ten and nine months, respectively. One patient, number 5, treated with steroids, danazol and rituximab did not relapse within four years of follow-up and Patient 6, who received steroids plus danazol did not relapse within three years of follow-up.CONCLUSION: Evans syndrome is an uncommon hematologic condition rarely diagnosed and not widely studied. Clinicians must have it in mind when evaluating a patient with a positive direct antiglobulin test, anemia and thrombocytopenia, since prognosis depends on its early recognition and opportune therapy, but even this leads to variable results.

  19. Hiro and Evans currents in Vertical Disruption Event

    Science.gov (United States)

    Zakharov, Leonid; Xujing Li Team; Sergei Galkin Team

    2014-10-01

    The notion of Tokamak Magneto-Hydrodynamics (TMHD), which explicitly reflects the anisotropy of a high temperature tokamak plasma is introduced. The set of TMHD equations is formulated for simulations of macroscopic plasma dynamics and disruptions in tokamaks. Free from the Courant restriction on the time step, this set of equations is appropriate for high performance plasmas and does not require any extension of the MHD plasma model. At the same time, TMHD requires the use of magnetic field aligned numerical grids. The TMHD model was used for creation of theory of the Wall Touching Kink and Vertical Modes (WTKM and WTVM), prediction of Hiro and Evans currents, design of an innovative diagnostics for Hiro current measurements, installed on EAST device. While Hiro currents have explained the toroidal asymmetry in the plasma current measurements in JET disruptions, the Evans currents explain the tile current measurements in tokamaks. The recently developed Vertical Disruption Code (VDE) have demonstrated 5 regimes of VDE and confirmed the generation of both Hiro and Evans currents. The results challenge the 24 years long misinterpretation of the tile currents in tokamaks as ``halo'' currents, which were a product of misuse of equilibrium reconstruction for VDE. This work is supported by US DoE Contract No. DE-AC02-09-CH1146.

  20. "I'm Telling You ... The Language Barrier Is the Most, the Biggest Challenge": Barriers to Education among Karen Refugee Women in Australia

    Science.gov (United States)

    Watkins, Paula G.; Razee, Husna; Richters, Juliet

    2012-01-01

    This article examines factors influencing English language education, participation and achievement among Karen refugee women in Australia. Data were drawn from ethnographic observations and interviews with 67 participants between 2009 and 2011, collected as part of a larger qualitative study exploring the well-being of Karen refugee women in…

  1. The "Everyday Politics" of IDP Protection in Karen State Flüchtlingspolitik im Karen-Gebiet

    Directory of Open Access Journals (Sweden)

    Stephen Hull

    2009-07-01

    Full Text Available While international humanitarian access in Burma has opened up over the past decade and a half, the ongoing debate regarding the appropriate relationship between politics and humanitarian assistance remains unresolved. This debate has become especially limiting in regards to protection measures for internally displaced persons (IDPs which are increasingly seen to fall within the mandate of humanitarian agencies. Conventional IDP protection frameworks are biased towards a top-down model of politicallyaverse intervention which marginalises local initiatives to resist abuse and hinders local control over protection efforts. Yet such local resistance strategies remain the most effective IDP protection measures currently employed in Karen State and other parts of rural Burma. Addressing the protection needs and underlying humanitarian concerns of displaced and potentially displaced people is thus inseparable from engagement with the "everyday politics" of rural villagers. This article seeks to challenge conventional notions of IDP protection that prioritise a form of state-centric "neutrality" and marginalise the "everyday politics" through which local villagers continue to resist abuse and claim their rights. Obwohl der Zugang internationaler Hilfsorganisationen nach Burma sich in der vergangenen Dekade verbessert hat, bleibt die Debatte über die angemessene Beziehung zwischen Politik und humanitärer Hilfe ungelöst. Die Debatte ist insbesondere bei Fragen des Schutzes von Binnenflüchtlingen (IDPs sehr begrenzt, die mehr und mehr unter den Schutz humanitärer Hilfsorganisationen fallen. Der konventionelle Rahmen des Schutzes von IDPs basiert auf einem Top-Down-Modell, das sich gegen eine politische Einflussnahme ausspricht, lokale Initiativen zum Schutz gegen Missbrauch marginalisiert und lokale Kontrolle über Schutzmaßnahmen verhindert. Lokale Widerstandsstrategien bleiben aber im gegenwärtigen Karen-Staat und in anderen Teilen des l

  2. Narratives and the Constitution of a Common Identity : The Karen in Burma

    NARCIS (Netherlands)

    Kuroiwa, Yoko; Verkuyten, Maykel

    2008-01-01

    This research was conducted in an informal school located in Thailand at the border with Myanmar (Burma) and supervised by the Karen National Union (KNU). The KNU has claimed and fought for political autonomy and independence from the Burmese government for more than a half century. The authors

  3. Domestication and Mistranslation of Oriental Jewelries and Music in Edmond O’Donovan’s The Merv Oasis

    Directory of Open Access Journals (Sweden)

    Ahmad Gholi

    2017-03-01

    Full Text Available From the perspective of a translation scholar like Susan Bassnett, travel writing is not dissimilar to translation. Like a translator, travel writer translates his traversed culture (i.e., target culture for the consumption of his/her home readership. Similar to textual translation, this cultural translation can be either successful or doomed, contingent on the travel writer cum cultural translator’s translation: does he/she translate on the basis of foreignization or domestication or mistranslate? The current article draws on Bassett’s cultural translation theory as its analytical tool and applies to Edmond O’Donovan’s travelogue, The Merv Oasis to illustrate how this travel writer as a cultural translator in his journey to Oriental locus both domesticates and mistranslate his encountered culture in particular his female travelees’ jewelries as well as their very indigenous music.

  4. Assessing awareness and knowledge of hypertension in an at-risk population in the Karen ethnic rural community, Thasongyang, Thailand

    Directory of Open Access Journals (Sweden)

    Aung MN

    2012-06-01

    Full Text Available Myo Nyein Aung,1,2 Thaworn Lorga,2 Janthila Srikrajang,2 Nongluk Promtingkran,2 Suchart Kreuangchai,2 Wilawan Tonpanya,2 Phatchanan Vivarakanon,2 Puangpet Jaiin,2 Nara Praipaksin,3 Apiradee Payaprom41Department of Public Health, Graduate School of Medicine, Juntendo University, Tokyo, Japan; 2Boromarajonani College of Nursing Nakhon Lampang (BCNLP, Lampang, Thailand; 3Baan Rekati Health Station, Thasongyang, Thailand; 4Thasongyang Hospital, ThailandBackground: Hypertension is currently a global health concern. Rural and minority populations are increasingly exposed to risk factors as a result of urbanization, leading to hypertension and cardiovascular disease. We conducted a survey in the rural Karen community in Thasongyang District, Tak Province, Thailand, with the aims of determining: the distribution of blood pressure across different age groups; the prevalence of hypertension and other risk factors for cardiovascular diseases (CVDs, including diabetes, smoking, sedentary lifestyle, and excess alcohol use; knowledge and awareness of hypertension as a disease; and knowledge and awareness of risk factors for hypertension among the population at risk.Methods: This was a community-based, cross-sectional survey of 298 rural Karen residents. A set of questionnaires assessing lifestyle-related health risk behaviors and awareness and knowledge of hypertension were used. Blood pressure, fasting plasma glucose, weight, height, and waist circumference were measured.Results: Median systolic and diastolic blood pressures were 110 (range 100–120 mmHg and 70 (range 60–80 mmHg, respectively. High blood pressure was observed in more than 27% of the population, with 15% being hypertensive and 12% being prehypertensive. Multinomial logistic regression analysis showed that people in the Karen community who were aware of hypertension were less likely to be current smokers (odds ratio [OR] 0.53, confidence interval [CI] 0.29–0.97 and those with primary

  5. Assessing awareness and knowledge of hypertension in an at-risk population in the Karen ethnic rural community, Thasongyang, Thailand.

    Science.gov (United States)

    Aung, Myo Nyein; Lorga, Thaworn; Srikrajang, Janthila; Promtingkran, Nongluk; Kreuangchai, Suchart; Tonpanya, Wilawan; Vivarakanon, Phatchanan; Jaiin, Puangpet; Praipaksin, Nara; Payaprom, Apiradee

    2012-01-01

    Hypertension is currently a global health concern. Rural and minority populations are increasingly exposed to risk factors as a result of urbanization, leading to hypertension and cardiovascular disease. We conducted a survey in the rural Karen community in Thasongyang District, Tak Province, Thailand, with the aims of determining: the distribution of blood pressure across different age groups; the prevalence of hypertension and other risk factors for cardiovascular diseases (CVDs), including diabetes, smoking, sedentary lifestyle, and excess alcohol use; knowledge and awareness of hypertension as a disease; and knowledge and awareness of risk factors for hypertension among the population at risk. This was a community-based, cross-sectional survey of 298 rural Karen residents. A set of questionnaires assessing lifestyle-related health risk behaviors and awareness and knowledge of hypertension were used. Blood pressure, fasting plasma glucose, weight, height, and waist circumference were measured. Median systolic and diastolic blood pressures were 110 (range 100-120) mmHg and 70 (range 60-80) mmHg, respectively. High blood pressure was observed in more than 27% of the population, with 15% being hypertensive and 12% being prehypertensive. Multinomial logistic regression analysis showed that people in the Karen community who were aware of hypertension were less likely to be current smokers (odds ratio [OR] 0.53, confidence interval [CI] 0.29-0.97) and those with primary school education were more likely to be aware of hypertension than those who did not have a primary school education (OR 6.5, CI 1.9-22.24). Overall, our survey showed that less than half of the Karen community had such knowledge and awareness. It is urgently necessary to promote knowledge, awareness, and health literacy among the ethnic Karen tribes to prevent hypertension and associated CVDs.

  6. Automated method to compute Evans index for diagnosis of idiopathic normal pressure hydrocephalus on brain CT images

    Science.gov (United States)

    Takahashi, Noriyuki; Kinoshita, Toshibumi; Ohmura, Tomomi; Matsuyama, Eri; Toyoshima, Hideto

    2017-03-01

    The early diagnosis of idiopathic normal pressure hydrocephalus (iNPH) considered as a treatable dementia is important. The iNPH causes enlargement of lateral ventricles (LVs). The degree of the enlargement of the LVs on CT or MR images is evaluated by using a diagnostic imaging criterion, Evans index. Evans index is defined as the ratio of the maximal width of frontal horns (FH) of the LVs to the maximal width of the inner skull (IS). Evans index is the most commonly used parameter for the evaluation of ventricular enlargement. However, manual measurement of Evans index is a time-consuming process. In this study, we present an automated method to compute Evans index on brain CT images. The algorithm of the method consisted of five major steps: standardization of CT data to an atlas, extraction of FH and IS regions, the search for the outmost points of bilateral FH regions, determination of the maximal widths of both the FH and the IS, and calculation of Evans index. The standardization to the atlas was performed by using linear affine transformation and non-linear wrapping techniques. The FH regions were segmented by using a three dimensional region growing technique. This scheme was applied to CT scans from 44 subjects, including 13 iNPH patients. The average difference in Evans index between the proposed method and manual measurement was 0.01 (1.6%), and the correlation coefficient of these data for the Evans index was 0.98. Therefore, this computerized method may have the potential to accurately compute Evans index for the diagnosis of iNPH on CT images.

  7. Cardiovascular Disease-related Health Beliefs and Lifestyle Issues Among Karen Refugees Resettled in the United States From the Thai-Myanmar (Burma) Border.

    Science.gov (United States)

    Kamimura, Akiko; Sin, Kai; Pye, Mu; Meng, Hsien-Wen

    2017-11-01

    Refugees resettled in the US may be at risk for cardiovascular disease (CVD). However, little is known about CVD-related issues among Karen refugees who have migrated to the US from the Thai-Myanmar border. The purpose of this study was to examine CVD-related health beliefs and lifestyle issues among Karen refugees resettled in the US. Karen refugees resettled in the US from the Thai-Myanmar border (n=195) participated in a survey study on health beliefs related to CVD, salt intake, physical activity (PA), and smoking in the fall of 2016. A high-salt diet, physical inactivity, and smoking were major lifestyle problems. Participants who adhered to a low-salt diet considered themselves to be susceptible to CVD. Most participants did not engage in regular PA. Regular PA was associated with less perceived susceptibility to CVD and greater perceived benefits of a healthy lifestyle for decreasing the likelihood of CVD. Each refugee population may require individualized strategies to promote PA and a healthy diet. Future studies should develop health education programs that are specifically designed for Karen refugees and evaluate such programs. In addition to health education programs on healthy lifestyle choices, tobacco cessation programs seem to be necessary for Karen refugees. At the same time, it is important to foster strategies to increase the utilization of preventive care among this population by promoting free or reduced-fee resources in the community to further promote their health.

  8. Researchers and the translational reality. Interview with Karen Aboody.

    Science.gov (United States)

    Aboody, Karen

    2012-11-01

    Karen Aboody has first-hand experience of taking a potential therapy from the laboratory into clinical trials. Here, she shares with us the challenges and rewards of going from bench to bedside, and why all biomedical researchers need to know what it takes to make the transition if they want the best chance of seeing their discoveries used to help patients. Karen Aboody received her MD at Mount Sinai School of Medicine, and completed her post-doctoral training in Molecular Neurogenetics at Massachusetts General Hospital, Harvard Medical School. After gaining experience in pathology, gene therapy and biotechnology, she joined City of Hope (COH) in 2003 to head a translational research laboratory focused on therapeutic stem cell applications for invasive and metastatic solid tumors. In 2010, she received US FDA approval for a first-in-human clinical trial for neural stem cell-mediated therapy for high-grade glioma patients. This Phase I study is ongoing at COH, supported by NCI/NIH funding. In 2010, she received an US$18 million California Institute of Regenerative Medicine Disease Team Award to develop a second-generation enzyme/prodrug stem cell-mediated brain tumor therapy for clinical trials that may also have applications for other metastatic cancers. Honors include the 2000 AANS Young Investigator Award, and 2008 ASGCT Outstanding New Investigator Award. She recently founded a clinical-stage biopharmaceutical company, TheraBiologics Inc., to support clinical development of neural stem cell-mediated cancer therapies.

  9. British Museum paintings

    OpenAIRE

    Edmonds, Frances

    2011-01-01

    Frances Edmonds is one of a group of artists selected for the show ‘Territories’ taking place at Galerie Windkracht 13 in Den Helder, Holland this July 2012. This exhibition is curated by Sharon Beavan and Gethin Evans. The artists represented work across the boundaries of two and three-dimensional and time based form. The brief – to interrogate and explore the notion of territories. Frances will be showing several paintings from the British Museum series, based on imagery collected ...

  10. The influence of administrative leadership: an interview with Dr Karen S. Hill.

    Science.gov (United States)

    Hill, Karen S; Adams, Jeffrey M

    2015-01-01

    This department highlights nursing leaders who have demonstrated a commitment to patient care leadership and innovation in practice, policy, research, education, and theory. This interview profiles Karen Hill, DNP, RN, NEA-BC, FACHE, FAAN, chief operating officer and chief nursing officer of Baptist Health in Lexington, Kentucky, and editor-in-chief of the Journal of Nursing Administration.

  11. Burma/Myanmar: Challenges of a Ceasefire Accord in Karen State Burma/Myanmar: Herausforderungen eines Waffenstillstandsabkommens im Karen-Staat

    Directory of Open Access Journals (Sweden)

    Paul Core

    2009-10-01

    Full Text Available Burma (Myanmar has seen some of the longest-running insurgencies in the world, which have had a devastating effect on local populations and the country as a whole. While the Karen National Union (KNU, which has fought successive Burmese governments since 1949, is in a critical phase of its life, the KNU/KNLA Peace Council (KPC is experiencing life under a ceasefire accord with the Burmese government, the State Peace and Development Council (SPDC. Major challenges have occurred since the ceasefire and future developments are uncertain. Like all ceasefire groups in the country, the KPC has come under immense pressure to follow the government’s “seven-step road map” to democracy, compete in the 2010 elections, and transform its troops into a border guard force under the control of the Burmese military or face disarmament. This article seeks to provide some insights into a ceasefire group, to analyse the failures and successes of the ceasefire accord, and to outline future challenges to the country. Myanmar (Burma ist bis heute Schauplatz von anhaltenden ethnischen Konflikten, welche einen erheblichen Einfluss auf lokale Bevölkerungen und das ganze Land haben. Während die Karen National Union, die seit dem Jahr 1949 gegen die burmesische Regierung kämpft, sich in einer kritischen Phase befindet, hat das KNU/KNLA Peace Council seinen eigenen Frieden mit der Militärregierung geschlossen. Seit dem Waffenstillstand haben sich erhebliche Herausforderungen aufgetan und zukünftige Entwicklungen sind ungewiss. Wie alle Waffenstillstandsgruppen im Land steht die Gruppe unter dem Druck der Regierung, dem „Sieben-Punkte-Fahrplan zur disziplinierten Demokratie“ zu folgen und damit eine politische Partei zu gründen sowie seine Truppen in eine Grenztruppe unter Kontrolle des burmesischen Militärs zu transformieren. Dieser Artikel gibt einen Einblick in eine Waffenstillstandsgruppe, analysiert die Erfolge sowie Misserfolge des

  12. 'J-KAREN' - high intensity, high contrast laser

    International Nuclear Information System (INIS)

    Kiriyama, Hiromitsu; Mori, Michiaki; Nakai, Yoshiki; Okada, Hajime; Sasao, Hajime; Sagisaka, Akito; Ochi, Yoshihiro; Tanaka, Momoko; Kondo, Kiminori; Tateno, Ryo; Sugiyama, Akira; Daido, Hiroyuki; Koike, Masato; Kawanishi, Syunichi; Shimomura, Takuya; Tanoue, Manabu; Wakai, Daisuke; Kondo, Shuji; Kanazawa, Shuhei

    2010-01-01

    We report on the high intensity, high contrast double chirped-pulse amplification (CPA) Ti:sapphire laser system (named J-KAREN). By use of an optical parametric chirped-pulse amplification (OPCPA) preamplifier that is seeded by a cleaned high-energy pulse, a background amplified spontaneous emission (ASE) level of 10 -10 relative to the peak main femtosecond pulse on the picosecond timescales demonstrated with an output energy of 1.7 J and a pulse duration of 30 fs, corresponding to a peak power of 60TW at a 10 Hz repetition rate. This system which uses a cryogenically-cooled Ti:sapphire final amplifier generates focused peak intensity in excess of 10 20 W/cm 2 at a 10 Hz repetition rate. (author)

  13. Comics Activism: An Interview with Comics Artist and Activist Kate Evans

    Directory of Open Access Journals (Sweden)

    Dominic Davies

    2017-11-01

    Full Text Available This is an interview with comics artist Kate Evans, author of 'Red Rosa' (2015 and 'Threads: From the Refugee Experience' (2017, as well as a number of other comics, about her recent work, which operates at the intersection of several of the most exciting genre developments in comics in recent years. In the interview Evans reflects on recent shifts in comics journalism, as well as other trends in the field such as the rise of graphic memoir, through examples taken from Evans’s own work as well as that of Joe Sacco, Lynda Barry, Alison Bechdel and others.

  14. Use of the Edmonds-Reilly Model to model energy-sector impacts of greenhouse gas emissions control strategies

    International Nuclear Information System (INIS)

    Barns, D.W.; Edmonds, J.A.; Reilly, J.M.

    1992-01-01

    The purpose of this paper is to document the results of our application of the Edmonds-Reilly Model (ERM) using several scenarios provided in connection with the 1991 Energy Modeling Forum (EMF). The purpose of this session of the forum is to compare the efforts of several modeling teams using common assumptions to examine the energy sector impacts of strategies to control greenhouse gas emissions. Because the output of this exercise is data-rich, most of this exposition is in graphical form with the narrative serving mainly as a roadmap for moving from one highlight to the next. The following sessions briefly describe the model and some of the special modifications made for this effort. The case-by-case discussion is contained in Section IV, followed by a summary of the potential pitfalls involved in attempting to assess the cost of emissions reduction from the model data

  15. Soul / Randy Becker, Bill Evans, Evelin Samuel ; interv. Sven Sapelson

    Index Scriptorium Estoniae

    Becker, Randy

    2007-01-01

    The Soulbop Bandi rajajad Randy Becker ja Bill Evans ning meie Evelin Samuel gospeli ja rhytmblues'i juurtega soulist. Lk. 72-73 Inessa Josingu ja Ande Kaalepi souliteemaline fotolavastusega ruumikujundus

  16. Extremely High Prevalence of Metronidazole-Resistant Helicobacter pylori Strains in Mountain People (Karen and Hmong) in Thailand.

    Science.gov (United States)

    Vilaichone, Ratha-korn; Ratanachu-Ek, Thawee; Gamnarai, Pornpen; Chaithongrat, Supakarn; Uchida, Tomahisa; Yamaoka, Yoshio; Mahachai, Varocha

    2016-04-01

    This study aimed to survey the prevalence, patterns of antibiotic resistance, and clinical factors associated with antibiotic resistance in Helicobacter pylori among the Karen and Hmong mountain people of Thailand. We recruited dyspeptic patients in the Maesod district, Tak Province, Thailand. All subjects underwent upper gastrointestinal endoscopy, and three antral gastric biopsies were obtained for rapid urease tests and culture. An epsilometer was used to determine the minimum inhibitory concentrations of amoxicillin (AMX), clarithromycin (CLR), metronidazole (MNZ), levofloxacin (LVX), ciprofloxacin (CIP), and tetracycline (TET). A total of 291 subjects were enrolled; 149 (51.2%) were infected with H. pylori. Helicobacter pylori infection was present in 47.1% of Thai, 51.7% of Karen, and 58.7% of Hmong subjects. Antibiotic resistance was present in 75.8% including AMX (0.8%), TET (0%), CLR (5.6%), MNZ (71.8%), CIP (19.4%), LVX (19.4%), and multidrug resistance in 21.8%. Karen subjects had the highest prevalence of MNZ resistance (84.6%), and Hmong subjects had the highest prevalence of fluoroquinolone (27.3%) and multidrug (34.1%) resistance. MNZ plus fluoroquinolone (14.5%) was the most common multidrug resistance. There was no association between clinical factors and antibiotic resistance. MNZ resistance was prevalent, whereas fluoroquinolone- and multidrug-resistant H. pylori infections are important problems in mountain people of Thailand. © The American Society of Tropical Medicine and Hygiene.

  17. Optimizing the Internal Medicine Clinic at Evans Army Community Hospital

    National Research Council Canada - National Science Library

    Bonilla, Jose

    2003-01-01

    ...) 2002, the Internal Medicine (IM) clinic at Evans Army Community Hospital, Fort Carson, Colorado, failed to meet access to care standards for routine appointments, and was only marginally successful in meeting standards for urgent appointments...

  18. O fantasma de Evans-Pritchard: diálogos da antropologia com a sua história The ghost of Evans-Pritchard: anthropology’s dialogues with its own history

    Directory of Open Access Journals (Sweden)

    Frederico Delgado Rosa

    2011-06-01

    Full Text Available Tomando como estudo de caso a monografia de Sharon Hutchinson sobre os nuer, o presente artigo explora os quiproquós do diálogo entre a antropologia contemporânea e os clássicos, procurando detetar certas genealogias invisíveis que remontam aos funcionalistas britânicos, e nomeadamente a Evans-Pritchard. Procede a um esbatimento de certas oposições explícitas entre o presente e o passado da antropologia, revelando que as noções clássicas perpassam de forma subterrânea o discurso daqueles que dizem rejeitá-las e que muitas das preocupações atuais já tinham expressão nas etnografias modernas. É demonstrado que as abordagens estáticas - como a de Evans-Pritchard - tinham uma componente histórica e que a antropologia social britânica teve as suas respostas teóricas e metodológicas para as transformações dos contextos africanos sob domínio colonial.Through the reading of Sharon Hutchinson’s monograph on the Nuer, this article explores the misunderstandings between contemporary anthropology and the modern classics. It tries to identify invisible genealogies that go back to the British functionalists, particularly to Evans-Pritchard, and minimizes the explicit oppositions between the present and the past of anthropology. It reveals that some classical notions are detectable in non-explicit ways among those who claim to reject them and, at the same time, that contemporary concerns have their roots in modern ethnographies. The author shows that static approaches - as the one by Evans-Pritchard on the Nuer - had a historical meaning and recalls that British social anthropology had its own theoretical and methodological answers to the transformations of African contexts under colonial rule.

  19. Challenging Expertise: Paul Feyerabend vs. Harry Collins & Robert Evans on democracy, public participation and scientific authority: Paul Feyerabend vs. Harry Collins & Robert Evans on scientific authority and public participation.

    Science.gov (United States)

    Sorgner, Helene

    2016-06-01

    This paper compares Feyerabend's arguments in Science in a Free Society to the controversial theory of expertise proposed by Harry Collins and Robert Evans as a Third Wave of Science Studies. Is the legitimacy of democratic decisions threatened by the unquestioned authority of scientific advice? Or does, on the contrary, science need protection from too much democratic participation in technical decisions? Where Feyerabend's political relativism envisions democratic society as inherently pluralist and demands equal contribution of all traditions and worldviews to public decision-making, Collins and Evans hold a conception of elective modernism, defending the reality and value of technical expertise and arguing that science deserves a privileged status in modern democracies, because scientific values are also democratic values. I will argue that Feyerabend's political relativism provides a valuable framework for the evaluation of Collins' and Evans' theory of expertise. By constructing a dialog between Feyerabend and this more recent approach in Science and Technology Studies, the aim of this article is not only to show where the two positions differ and in what way they might be reconciled, but also how Feyerabend's philosophy provides substantial input to contemporary debate. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Lyn Evans decelerates!

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    After more than 40 years at CERN, 15 of which were dedicated to ensuring that the LHC comes to completion, Lyn Evans is retiring. The Imperial College Professor and recently-elected Fellow of the British Royal Society has set himself new challenges, but plans to keep strong links with CERN. His big thank you goes to the many hundreds of people who built one of the most complex scientific instruments ever conceived by mankind. Note from the Editor: It is unusual for the Bulletin to adopt a question-and-answer style. However, we recognise that, with someone of Lyn’s stature, the appropriate thing to do is simply to give him the floor. Bulletin: Lyn, are you really leaving CERN? I am retiring but I will not completely lose contacts with CERN and the LHC. It’s time to slow down for me now but I will join the CMS Collaboration. I will help with the link between the experiment and the machine. Bulletin: After many years as LHC Project Manager...

  1. Evans Blue Dye: A Revisit of Its Applications in Biomedicine.

    Science.gov (United States)

    Yao, Linpeng; Xue, Xing; Yu, Peipei; Ni, Yicheng; Chen, Feng

    2018-01-01

    Evans blue (EB) dye has owned a long history as a biological dye and diagnostic agent since its first staining application by Herbert McLean Evans in 1914. Due to its high water solubility and slow excretion, as well as its tight binding to serum albumin, EB has been widely used in biomedicine, including its use in estimating blood volume and vascular permeability, detecting lymph nodes, and localizing the tumor lesions. Recently, a series of EB derivatives have been labeled with PET isotopes and can be used as theranostics with a broad potential due to their improved half-life in the blood and reduced release. Some of EB derivatives have even been used in translational applications in clinics. In addition, a novel necrosis-avid feature of EB has recently been reported in some preclinical animal studies. Given all these interesting and important advances in EB study, a comprehensive revisiting of EB has been made in its biomedical applications in the review.

  2. "Here nobody holds your heart": metaphoric and embodied emotions of birth and displacement among Karen women in Australia.

    Science.gov (United States)

    Niner, Sara; Kokanovic, Renata; Cuthbert, Denise; Cho, Violet

    2014-09-01

    Our objective was to explore the ways in which displaced Karen mothers expressed emotions in narrative accounts of motherhood and displacement. We contextualized and analyzed interview data from an ethnographic study of birth and emotions among 15 displaced Karen mothers in Australia. We found that women shared a common symbolic language to describe emotions centered on the heart, which was also associated with heart "problems." This, along with hypertension, collapsing, or a feeling of surrender were associated responses to extremely adverse events experienced as displaced peoples. A metaphoric schema of emotional terms centered on the heart was connected to embodied expressions of emotion related to illness of the heart. This and other embodied responses were reactions to overwhelming difficulties and fear women endured due to their exposure to political conflict and global inequity. © 2014 by the American Anthropological Association.

  3. Ethnomedicinal plants used for digestive system disorders by the Karen of northern Thailand.

    Science.gov (United States)

    Tangjitman, Kornkanok; Wongsawad, Chalobol; Kamwong, Kaweesin; Sukkho, Treetip; Trisonthi, Chusie

    2015-04-09

    Digestive system disorders have a substantial effect on worldwide morbidity and mortality rates, including in Thailand, where the majority of the rural areas have a lack of proper sanitation and awareness about disease prevention. This has led to the prevalence of different types of digestive diseases. Karen people in Thailand still use medicinal plants as first aid remedies in treating these diseases. Therefore, this study aimed at documenting the plants used to cure and prevent different types of digestive system disorders by Karen people of Chiang Mai Province, northern Thailand. Ethnomedicinal data were collected from six key informants and 172 non-specialist informants regarding their traditional knowledge of medicinal plants. Quantitative approaches were used to determine Use Value (UV), Informant Consensus Factor (ICF) and Fidelity Level (FL) values. The study revealed that 36 medicinal plant species belonging to 31 genera and 24 families were used to treat digestive system disorders. The most prevalent plant families were Zingiberaceae (6 species), Euphorbiaceae (4 species) and Fabaceae (4 species). Leaves were the most commonly used plant part accounting for 32.6% of the plants, followed by the bark (18.6%). About 60% of the administrations were given orally by potion (60%) and consumption as food was also indicated (14%). The highest ICF values were recorded for carminative disorders, stomachaches, geographic tongue, constipation, appetite stimulants and food poisoning (1.00 each) indicating the best agreement among the informants knowledge of medicinal plants that were used to treat aliments in these categories. The highest fidelity level values were recorded for Punica granatum (100.00), Psidium guajava (95.45), and Gymnopetalum integrifolium (90.91) showing conformity of knowledge on species with the best healing potential. Medicinal plants still play an important role among Karen culture. The present information on these medicinal plants, which have

  4. Effectiveness of cyclosporine and mycophenolate mofetil in a child with refractory evans syndrome

    Directory of Open Access Journals (Sweden)

    Piero Farruggia

    2011-05-01

    Full Text Available Evans Syndrome is a rare autoimmune disease consisting of hemolytic anemia, thrombocytopenia and/or neutropenia. It may be associated with other autoimmune or lymphoproliferative diseases. Its course can be extremely serious and, rarely, even life-threatening; thus it represents a excellent treatment challenge for the pediatric hematologist. First line treatment consists of steroids and/or immunoglobulin; further therapy with rituximab, vincristine, cyclophosphamide and other immunosuppressive drugs can be considered in unresponsive patients. We describe a baby with refractory Evans Syndrome that was cured by prolonged administration of mycophenolate mofetil and remained disease-free for 4 years after the discontinuation of treatment.

  5. Public knowledge of diabetes in Karen Ethnic rural residents: a community-based questionnaires study in the far north-west of Thailand

    Directory of Open Access Journals (Sweden)

    Lorga T

    2012-09-01

    Full Text Available Thaworn Lorga,1 Kannapatch Srithong,1 Pratumpan Manokulanan,1 Thin Nyein Nyein Aung,2 Myo Nyein Aung1,31Boromrajonani College of Nursing Nakhon Lampang (BCNLP, Lampang, Thailand; 2University of Medicine, Mandalay, Myanmar; 3Department of Public Health, Graduate School of Medicine Juntendo University, Tokyo, JapanBackground and purpose: The public knowledge of diabetes is important for prevention of disease. This study aimed to evaluate knowledge of diabetes, risk factors, and the common warning signs of diabetes and complications among community participants in a rural Karen ethnic community.Methods: Participants were asked to answer a questionnaire regarding their knowledge of diabetes. Fasting blood glucose testing, blood pressure measurement, and body mass index (BMI assessment were provided to the participants. The study was conducted at Thasongyang district, Tak province, Thailand.Results: A total of 299 Karen rural residents were included in the study. The median age was 45 years and median fasting blood glucose was 88 mg/dL. The response rate to the questionnaires was 91.97%. Half of the participants knew diabetes is a noncommunicable disease needing lifelong treatment. Overall, one-third of the community participants could correctly answer the knowledge assessment questions regarding risk factors and common features of diabetes. Whereas the other two-thirds either gave a wrong answer or were “not sure”. Female participants had poorer diabetes knowledge than the males.Conclusion: The public knowledge of diabetes, as represented by this sample of the Karen ethic community, is alarmingly low. There is significant gender difference in knowledge level. Culturally tailored and gender-sensitive diabetes health education interventions are urgently needed in this minority ethnic community.Keywords: health education, gender differences, ethnic minority, diabetes, Karen

  6. Enantioselective Evans-Tishchenko Reduction of b-Hydroxyketone Catalyzed by Lithium Binaphtholate

    Directory of Open Access Journals (Sweden)

    Makoto Nakajima

    2011-06-01

    Full Text Available Lithium diphenylbinaphtholate catalyzed the enantioselective Evans-Tishchenko reduction of achiral b-hydroxyketones to afford monoacyl-protected 1,3-diols with high stereoselectivities. In the reaction of racemic b-hydroxyketones, kinetic optical resolution occurred in a highly stereoselective manner.

  7. Diplodia natalensis , Pole Evans: a causal agent of citrus gummosis ...

    African Journals Online (AJOL)

    Isolations were made from the barks of gummosis-infected citrus trees from orchards of the University of Ghana Agricultural Research Station at Kade. The isolation media used were 1.5% water agar, 1.5% water agar + nystatin and 1.5% water agar + benomyl. Four isolates including Diplodia natalensis Pole Evans, ...

  8. Henri Cartier-Bresson / Walker Evans : Photographier l’Amérique (1929-1947

    Directory of Open Access Journals (Sweden)

    François Brunet

    2009-08-01

    Full Text Available Dans un mot adressé en 2001 à Peter Galassi, conservateur de la photographie au MOMA, Henri Cartier-Bresson, alors âgé de quatre-vingt-treize ans, écrivait plaisamment — mais non pas complaisamment : « If it had not been for the challenge of the work of Walker Evans, I don’t think I would have remained a fotographer » (« sans le défi constitué par le travail de Walker Evans, je ne crois pas que je serais resté fotographe ». Pour fêter le centenaire de Cartier-Bresson, c’est ce défi — plutôt ...

  9. Knowledge of communicable and noncommunicable diseases among Karen ethnic high school students in rural Thasongyang, the far northwest of Thailand.

    Science.gov (United States)

    Lorga, Thaworn; Aung, Myo Nyein; Naunboonruang, Prissana; Junlapeeya, Piyatida; Payaprom, Apiradee

    2013-01-01

    The double burden of communicable and noncommunicable diseases (NCD) is an increasing trend in low- and-middle income developing countries. Rural and minority populations are underserved and likely to be affected severely by these burdens. Knowledge among young people could provide immunity to such diseases within a community in the long term. In this study we aimed to assess the knowledge of several highly prevalent NCDs (diabetes, hypertension, and chronic obstructive pulmonary disease [COPD]) and several highly incident communicable diseases (malaria and diarrheal diseases) among Karen high school students in a rural district in far northwest of Thailand. The aim of the study is to explore information for devising life-course health education that will be strategically based in schools. A cross-sectional survey approved by the ethics committee of Boromarajonani College of Nursing Nakhon Lampang (BCNLP), Lampang, Thailand was conducted in Thasongyang, Tak province, from September 2011 to January 2012. Questionnaires for assessing knowledge regarding diabetes, hypertension, COPD, malaria, and diarrheal diseases were delivered to all 457 Karen high school students attending Thasongyang high school. A total of 371 students returned the questionnaires. Experts' validation and split-half reliability assessment was applied to the instrument. Students' main sources of health information were their teachers (62%), health care workers (60%), television (59%), and parents (54%). Familial risk factors of diabetes and hypertension were not known to more than two thirds of the students. Except obesity and physical inactivity, lifestyle-related risk factors were also not known to the students. Though living in a malaria-endemic area, many of the Karen students had poor knowledge about preventive behaviors. Half of the students could not give a correct answer about the malaria and hygienic practice, which might normally be traditionally relayed messages. Health education and

  10. Public knowledge of diabetes in Karen Ethnic rural residents: a community-based questionnaires study in the far north-west of Thailand.

    Science.gov (United States)

    Lorga, Thaworn; Srithong, Kannapatch; Manokulanan, Pratumpan; Aung, Thin Nyein Nyein; Aung, Myo Nyein

    2012-01-01

    The public knowledge of diabetes is important for prevention of disease. This study aimed to evaluate knowledge of diabetes, risk factors, and the common warning signs of diabetes and complications among community participants in a rural Karen ethnic community. Participants were asked to answer a questionnaire regarding their knowledge of diabetes. Fasting blood glucose testing, blood pressure measurement, and body mass index (BMI) assessment were provided to the participants. The study was conducted at Thasongyang district, Tak province, Thailand. A total of 299 Karen rural residents were included in the study. The median age was 45 years and median fasting blood glucose was 88 mg/dL. The response rate to the questionnaires was 91.97%. Half of the participants knew diabetes is a noncommunicable disease needing lifelong treatment. Overall, one-third of the community participants could correctly answer the knowledge assessment questions regarding risk factors and common features of diabetes. whereas the other two-thirds either gave a wrong answer or were "not sure". Female participants had poorer diabetes knowledge than the males. The public knowledge of diabetes, as represented by this sample of the Karen ethic community, is alarmingly low. There is significant gender difference in knowledge level. Culturally tailored and gender-sensitive diabetes health education interventions are urgently needed in this minority ethnic community.

  11. Posthumous Pardons, the Home Office and the Timothy Evans Case

    OpenAIRE

    Rubin, Gerry

    2007-01-01

    Examines the legal issues surrounding the exercise of the prerogative of mercy to grant posthumous pardons either to those convicted of a capital offence or those executed for offences under military law, specifically during the First World War. Focuses on the policy considerations leading to the Home Secretary’s decision to recommend the grant of a posthumous pardon for Timothy Evans in 1966.

  12. Medicinal plants from swidden fallows and sacred forest of the Karen and the Lawa in Thailand.

    Science.gov (United States)

    Junsongduang, Auemporn; Balslev, Henrik; Inta, Angkhana; Jampeetong, Arunothai; Wangpakapattanawong, Prasit

    2013-06-24

    Many ecosystem services provided by forests are important for the livelihoods of indigenous people. Sacred forests are used for traditional practices by the ethnic minorities in northern Thailand and they protect these forests that are important for their culture and daily life. Swidden fallow fields are a dominant feature of the agricultural farming landscapes in the region. In this study we evaluate and compare the importance of swidden fallow fields and sacred forests as providers of medicinal plants among the Karen and Lawa ethnic minorities in northern Thailand. We made plant inventories in swidden fallow fields of three different ages (1-2, 3-4, 5-6 years old) and in sacred forests around two villages using a replicated stratified design of vegetation plots. Subsequently we interviewed the villagers, using semi-structured questionnaires, to assess the medicinal use of the species encountered in the vegetation survey. We registered a total of 365 species in 244 genera and 82 families. Of these 72(19%) species in 60(24%) genera and 32(39%) families had medicinal uses. Although the sacred forest overall housed more species than the swidden fallow fields, about equal numbers of medicinal plants were derived from the forest and the fallows. This in turn means that a higher proportion (48% and 34%) of the species in the relatively species poor fallows were used for medicinal purposes than the proportion of medicinal plants from the sacred forest which accounted for 17-22%. Of the 32 medicinal plant families Euphorbiaceae and Lauraceae had most used species in the Karen and Lawa villages respectively. Sacred forest are important for providing medicinal plant species to the Karen and Lawa communities in northern Thailand, but the swidden fallows around the villages are equally important in terms of absolute numbers of medicinal plant species, and more important if counted as proportion of the total number of species in a habitat. This points to the importance of

  13. Monotypic no longer: a new species of Panca Evans (Lepidoptera: Hesperiidae: Hesperiinae: Moncini) from South America.

    Science.gov (United States)

    Dolibaina, Diego Rodrigo; Carneiro, Eduardo; Mielke, Olaf Hermann Hendrik; Casagrande, Mirna Martins; Lamas, Gerardo

    2017-05-19

    A new species belonging to the previously monotypic genus Panca Evans, 1955, P. moseri Dolibaina, Carneiro & O. Mielke sp. nov., from grasslands areas of Peru, Bolivia and Brazil is described. Adults and male and female genitalia of the new species are illustrated, described in detail, and compared with the type species of the genus, Lerodea subpunctuli Hayward, 1934, and with its externally most similar and sympatric species, Vidius mictra Evans, 1955. The systematic position of the genus Panca and its association with lowland open natural habitats of South America are discussed.

  14. Karen and Lawa medicinal plant use: uniformity or ethnic divergence?

    Science.gov (United States)

    Junsongduang, Auemporn; Balslev, Henrik; Inta, Angkhana; Jampeetong, Arunothai; Wangpakapattanawong, Prasit

    2014-01-01

    We here tease apart the ethnopharmacological knowledge of plants in two Thai villages to determine to which degree the uses are particular to individual ethnic groups and to which degree they are part of a generalized and uniform set of widespread medicinal plants used over a large geographic range. We compared Karen and Lawa knowledge of medicinal plants in the Mae Cheam watershed of northern Thailand, where both ethnic groups have settled and share ecological conditions for resource extraction. We were interested in documenting the degree to which these two ethnic groups use the same or different medicinal plant species. The use of the same plant species by the two groups was considered a sign of uniform and cross-cultural local knowledge, whereas the use of different medicinal plants by each group was considered a sign of culturally specific local knowledge that developed within each ethnic group. We inventoried the plant species in different habitats around one Karen village and one Lawa village using stratified vegetation plots and using semi-structured questionnaires we interviewed 67 key informants regarding their use of plants for medicine. We then calculated the Fidelity level FL (FL values near 100% for a species indicate that almost all use reports refer to the same way of using the species, whereas low FL values indicate that a species is used for many different purposes) and cultural importance index CI (the sum of the proportion of informants that mention each of the use categories for a given species) to estimate the variation in medicinal plant use. We used Jaccard's Index JI (This index relates the number of shared species to the total number of species) to analyze the similarity of medicinal plant use between the two villages. A total of 103 species of medicinal plant species in 87 genera and 41 families were identified and they were used to cure 35 ailments. The FL of the medicinal plant species varied from 10% to 100%, was different for each

  15. Spectral Analysis and Dirichlet Forms on Barlow-Evans Fractals

    OpenAIRE

    Steinhurst, Benjamin; Teplyaev, Alexander

    2012-01-01

    We show that if a Barlow-Evans Markov process on a vermiculated space is symmetric, then one can study the spectral properties of the corresponding Laplacian using projective limits. For some examples, such as the Laakso spaces and a Spierpinski P\\^ate \\`a Choux, one can develop a complete spectral theory, including the eigenfunction expansions that are analogous to Fourier series. Also, one can construct connected fractal spaces isospectral to the fractal strings of Lapidus and van Frankenhu...

  16. Vitamin A status of the minority ethnic group of Karen hill tribe children aged 1-6 years in Northern Thailand.

    Science.gov (United States)

    Tienboon, Prasong; Wangpakapattanawong, Prasit

    2007-01-01

    Vitamin A deficiency (VAD) is the most common cause of childhood blindness in the developing world. It is estimated that by giving adequate vitamin A, in vitamin A deficient populations, child mortality from measles can be reduced by 50%, and mortality from diarrheal disease by 40%. Overall mortality in children 6-59 months of age can be reduced by 23%. This paper reported results from a study of vitamin A status and malnutrition of the minority ethnic group of Karen hill tribe children aged 1-6 years in the north of Thailand. All children aged 1-6 years (N = 158; 83 boys, 75 girls) from the three Karen villages (Mae Hae Tai, Mae Yot, Mae Raek) of Mae Chaem district in the north of Thailand were studied. The Karen is the largest mountain ethnic minority ("hill tribe") group in Thailand. All children were examined by a qualified medical doctor and were assessed for their vitamin A intakes using 24 hours dietary recall. Thai food composition table from Ministry of Health, Thailand were used as references. The results were compared with the Thai Recommended Dietary Allowances. Children aged 1-3 years and 4-6 years were separately analysed due to the differences in Thai Recommended Dietary Allowances between the two age groups. A whole blood of 300 microL was obtained by "fingerstick" for determination of serum vitamin A. Community or village's vitamin A status was assessed by using Simplified Dietary Assessment (SDA) method and Helen Keller International (HKI) food frequency method. Descriptive statistics were used to analyse the data. All families of the study boys and girls had income lower than the Thailand poverty line (US $ 1,000/year). On average, 63% of children from Mae Hae Tai village, 1.5% of children from Mae Yot village and none of children from Mae Raek village had serum vitamin AKaren children in Mae Chaem district, recommendations were made as follow: (1) increased use of fat and oil, particularly in areas with high risk of VAD; (2) more general work

  17. Public Lecture | The long road to the LHC | Prof. Lyn Evans, Dr. Daniel Treille and Prof. Peter Jenni | 9 October

    CERN Document Server

    2014-01-01

    “The long road to the LHC” by Prof. Lyn Evans, Dr. Daniel Treille and Prof. Peter Jenni. Thursday 9 October, 7.30 p.m. in the Globe of Science and Innovation. Talk in English with simultaneous interpreting into French.  Entrance free. Limited number of seats. Reservation essential: +41 22 767 76 76 or cern.reception@cern.ch   Lyn Evans. Lecture by Lyn Evans Abstract The key to the discovery of the Higgs boson has been the development of particle accelerators at CERN over the years. I will explain how a particle accelerator works and will follow the path from the construction of the Proton Synchrotron in the 1950s to the world’s most powerful colliding beam machine, the Large Hadron Collider. Biography Born in 1945, Lyn Evans has spent his whole career in the field of high energy physics and particle accelerators, participating in all the great projects of CERN. From 1993 he led the team that designed, built and commissioned the LHC. He is currently ...

  18. Recenzja książki: James Evans, The history and practice of ancient astronomy, Oford University Press, 1998.

    OpenAIRE

    Dylewski, Jarosław

    2011-01-01

    Professor James Evans is a physicist working an University of Pudget Sound in the USA. His reseatch is focused on ancient astronomy and application of that knowledge. He also successfully attempted to build gnomon, astrolabe or analemna – instruments used in antuiquity and medieval times to make observations of celestial bodies. In his work, The History and Practice of Ancient Astronomy, professor Evans introduces the reader to the evolution of astronomical knowledge, from the simplest observ...

  19. The Evolving Science of Patient and Family Engagement: An Interview With Dr Karen Drenkard.

    Science.gov (United States)

    Reid-Ponte, Patricia

    2018-02-01

    Patient- and family-centered care is a central tenet of nursing practice. This concept has evolved to include patient partnerships, patient engagement, and patient activation. This column differentiates these concepts and describes the core principles embedded in the overriding intention of ensuring that patients (and their families or significant others) are orchestrators of their health and their care plans. In this interview, Karen Drenkard, PhD, RN, FAAN, NEA-BC, CNO, of the GetWellNetwork, discusses work by the O'Neil Center as a leader in this area.

  20. Joint reproductive autonomy: does Evans v Amicus Healthcare Ltd provide for a gender-neutral approach to assisted reproductive rights?

    Science.gov (United States)

    Allin, Michael J

    2015-06-01

    Assisted reproductive technology encompasses methods of achieving pregnancy by artificial or partially artificial means. Whilst these methods are more commonly used by couples suffering from problems of infertility, some forms of assistance are employed by fertile couples, for example pre-implantation genetic diagnosis. The overall regulatory framework in the UK is predominantly found in the Human Fertilisation and Embryology Act 1990. The usual rules relating to consent and autonomy apply and were discussed in depth in Evans v Amicus Healthcare Ltd and later in Evans v United Kingdom. This paper considers whether the Evans litigation envisages the possibility of further encouraging joint autonomy in the use of zygotes and whether there is a continuing right to autonomy by the party not bearing the pregnancy. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  1. Knowledge of communicable and noncommunicable diseases among Karen ethnic high school students in rural Thasongyang, the far northwest of Thailand

    Directory of Open Access Journals (Sweden)

    Lorga T

    2013-07-01

    Full Text Available Thaworn Lorga,1 Myo Nyein Aung,1,2 Prissana Naunboonruang,1 Piyatida Junlapeeya,1 Apiradee Payaprom31Boromarajonani College of Nursing Nakhon Lampang (BCNLP, Lampang, Thailand; 2Department of Public Health, Graduate School of Medicine, Juntendo University, Tokyo, Japan; 3Thasongyang Hospital, Thasongyang, Tak, ThailandBackground: The double burden of communicable and noncommunicable diseases (NCD is an increasing trend in low- and-middle income developing countries. Rural and minority populations are underserved and likely to be affected severely by these burdens. Knowledge among young people could provide immunity to such diseases within a community in the long term. In this study we aimed to assess the knowledge of several highly prevalent NCDs (diabetes, hypertension, and chronic obstructive pulmonary disease [COPD] and several highly incident communicable diseases (malaria and diarrheal diseases among Karen high school students in a rural district in far northwest of Thailand. The aim of the study is to explore information for devising life-course health education that will be strategically based in schools.Method: A cross-sectional survey approved by the ethics committee of Boromarajonani College of Nursing Nakhon Lampang (BCNLP, Lampang, Thailand was conducted in Thasongyang, Tak province, from September 2011 to January 2012. Questionnaires for assessing knowledge regarding diabetes, hypertension, COPD, malaria, and diarrheal diseases were delivered to all 457 Karen high school students attending Thasongyang high school. A total of 371 students returned the questionnaires. Experts' validation and split-half reliability assessment was applied to the instrument.Results: Students' main sources of health information were their teachers (62%, health care workers (60%, television (59%, and parents (54%. Familial risk factors of diabetes and hypertension were not known to more than two thirds of the students. Except obesity and physical

  2. Evans Syndrome Complicated by Intratubular Hemoglobin Cast Nephropathy

    Directory of Open Access Journals (Sweden)

    Iván González

    2017-01-01

    Full Text Available Evans syndrome (ES is a rare autoimmune disorder whose exact pathophysiology is unknown. It is characterized by the simultaneous or subsequent development of autoimmune hemolytic anemia (AIHA and immune thrombocytopenia (ITP. Intravascular hemolysis, with hemoglobinemia, is known to produce acute kidney injury; however, the development of intratubular hemoglobin casts (hemoglobin cast nephropathy in the setting of acute hemolysis is uncommon. Likewise, the association of ES and acute renal failure is equally uncommon. We present a case of a 7-year-old girl with ES who developed acute kidney injury in the setting of intravascular hemolysis and had widespread intratubular hemoglobin casts.

  3. Foam separation of Rhodamine-G and Evans Blue using a simple separatory bottle system.

    Science.gov (United States)

    Dasarathy, Dhweeja; Ito, Yoichiro

    2017-09-29

    A simple separatory glass bottle was used to improve separation effectiveness and cost efficiency while simultaneously creating a simpler system for separating biological compounds. Additionally, it was important to develop a scalable separation method so this would be applicable to both analytical and preparative separations. Compared to conventional foam separation methods, this method easily forms stable dry foam which ensures high purity of yielded fractions. A negatively charged surfactant, sodium dodecyl sulfate (SDS), was used as the ligand to carry a positively charged Rhodamine-G, leaving a negatively charged Evans Blue in the bottle. The performance of the separatory bottle was tested for separating Rhodamine-G from Evans Blue with sample sizes ranged from 1 to 12mg in preparative separations and 1-20μg in analytical separations under optimum conditions. These conditions including N 2 gas pressure, spinning speed of contents with a magnetic stirrer, concentration of the ligand, volume of the solvent, and concentration of the sample, were all modified and optimized. Based on the calculations at their peak absorbances, Rhodamine-G and Evans Blue were efficiently separated in times ranging from 1h to 3h, depending on sample volume. Optimal conditions were found to be 60psi N 2 pressure and 2mM SDS for the affinity ligand. This novel separation method will allow for rapid separation of biological compounds while simultaneously being scalable and cost effective. Published by Elsevier B.V.

  4. Katayama fever in scuba divers - A report of 3 cases | Evans | South ...

    African Journals Online (AJOL)

    Katayama fever in scuba divers - A report of 3 cases. A.C. Evans, D.J. Martin, B.D. Ginsburg. Abstract. Katayama fever or acute schistosomiasis probably occurs more commonly than is recorded. Interviews with a 3-man scuba diving team who had had contact with a large dam in an ·endemic area of the eastern Transvaal ...

  5. Sotsiaalne ettevõtlus lahendab murekohti / Mervi Raudsaar, Roger Evans ; intervjueerinud Merilyn Merisalu

    Index Scriptorium Estoniae

    Raudsaar, Mervi, 1975-

    2012-01-01

    TÜ ettevõtluskeskuse kaasabil loetakse kevadsemestril Tartu ülikoolis, Eesti maaülikoolis, Tallinna ülikoolis ja EBS-is inglise- ja eestikeelset õppeainet "Sotsiaalse ettevõtluse alused". Loenguid loevad TÜ majandusteaduskonna ettevõtluse assistent Mervi Raudsaar, külalisprofessor Roger Evans Šotimaalt ning Margarita Sokolova Heateo Sihtasutusest. Ainekursus valmib koostöös Heateo Sihtasutuse ja EASiga

  6. Chemoselective N-arylation of aminobenzamides via copper catalysed Chan-Evans-Lam reactions.

    Science.gov (United States)

    Liu, Shuai; Zu, Weisai; Zhang, Jinli; Xu, Liang

    2017-11-15

    Chemoselective N-arylation of unprotected aminobenzamides was achieved via Cu-catalysed Chan-Evans-Lam cross-coupling with aryl boronic acids for the first time. Simple copper catalysts enable the selective arylation of amino groups in ortho/meta/para-aminobenzamides under open-flask conditions. The reactions were scalable and compatible with a wide range of functional groups.

  7. Admixed origin of the Kayah (Red Karen) in Northern Thailand revealed by biparental and paternal markers.

    Science.gov (United States)

    Kutanan, Wibhu; Srikummool, Metawee; Pittayaporn, Pittayawat; Seielstad, Mark; Kangwanpong, Daoroong; Kumar, Vikrant; Prombanchachai, Thanawut; Chantawannakul, Panuwan

    2015-03-01

    This study analyzes the autosomal short tandem repeats (STRs) variation and the presence of Y chromosomal haplogroups from 44 individuals of the Kayah or Red Karen (KA) in Northern Thailand. The results based on autosomal STRs indicated that the KA exhibited closer genetic relatedness to populations from adjacent regions in Southeast Asia (SEA) than populations from Northeast Asia (NEA) and Tibet. Moreover, an admixed origin of the KA forming three population groups was observed: NEA, Southern China, and Northern Thailand. The NEA populations made a minor genetic contribution to the KA, while the rest came from populations speaking Sino-Tibetan (ST) languages from Southern China and Tai-Kadai (TK) speaking groups from Northern Thailand. The presence of six paternal haplogroups, composed of dual haplogroups prevalent in NEA (NO, N, and D1) and SEA (O2 and O3) as well as the intermediate genetic position of the KA between the SEA and NEA also indicated an admixed origin of male KA lineages. Our genetic results thus agree with findings in linguistics that Karenic languages are ST languages that became heavily influenced by TK during their southward spread. A result of the Mongol invasions during the 13th century A.D. is one possible explanation for genetic contribution of NEA to the KA. © 2015 John Wiley & Sons Ltd/University College London.

  8. Current prevalence of intestinal parasitic infections and their impact on hematological and nutritional status among Karen hill tribe children in Omkoi District, Chiang Mai Province, Thailand.

    Science.gov (United States)

    Yanola, Jintana; Nachaiwieng, Woottichai; Duangmano, Suwit; Prasannarong, Mujalin; Somboon, Pradya; Pornprasert, Sakorn

    2018-04-01

    Intestinal parasitic infection represents a substantial problem for children living in rural or limited resources areas and significantly relates to anemia and nutritional status. This study aimed to determine the current prevalence of intestinal parasitic infections among school-age children of Karen hill tribe population in Omkoi District, Chiang Mai Province, Thailand and assess the impact of intestinal parasitic infection on hematological and nutritional status in those children. A total of 375 Karen hill tribe children, 6-14 years of age, in Omkoi District were randomly selected to participate in this study. Stool samples were collected and examined for intestinal parasitic infection through formalin-ether concentration method. Blood samples were collected for hematological and iron analysis. The overall prevalence of intestinal parasitic infection was 47.7% (179/375), with single infections (29.3%) and polyparatism (18.4%). The most common pathogenic parasite was Trichuris trichiura (16.0%), followed by Ascaris lumbricoides (13%) and Giardia lamblia (3.5%). In addition, non-pathogenic amoeba, Entamoeba coli was observed with a high prevalence rate (31.2%). Anemia and eosinophilia prevalence were 6.40% (24/375) and 74.7% (280/375), respectively. Eosinophilia was significantly more prevalent in children with intestinal parasitic infection compared to uninfected children. Among 249 children, 13.7% were iron deficiency, 9.6% were thalassemia and hemoglobinophathy and 8% were G-6-PD deficiency. A high prevalence infection rate was significantly associated with eosinophilia, but independently related to anemia and iron deficiency. Intestinal parasitic infections are endemic in school-age children of Karen hill tribe population in Omkoi District. These data highlight the need for an integrated approach to control transmission of intestinal parasites and improve the health and sanitation status of Karen hill tribe children in Thailand. Copyright © 2018 Elsevier B

  9. Comparative Outcomes Between Step-Cut Lengthening Calcaneal Osteotomy vs Traditional Evans Osteotomy for Stage IIB Adult-Acquired Flatfoot Deformity.

    Science.gov (United States)

    Saunders, Stuart M; Ellis, Scott J; Demetracopoulos, Constantine A; Marinescu, Anca; Burkett, Jayme; Deland, Jonathan T

    2018-01-01

    The forefoot abduction component of the flexible adult-acquired flatfoot can be addressed with lengthening of the anterior process of the calcaneus. We hypothesized that the step-cut lengthening calcaneal osteotomy (SLCO) would decrease the incidence of nonunion, lead to improvement in clinical outcome scores, and have a faster time to healing compared with the traditional Evans osteotomy. We retrospectively reviewed 111 patients (143 total feet: 65 Evans, 78 SLCO) undergoing stage IIB reconstruction followed clinically for at least 2 years. Preoperative and postoperative radiographs were analyzed for the amount of deformity correction. Computed tomography (CT) was used to analyze osteotomy healing. The Foot and Ankle Outcome Scores (FAOS) and lateral pain surveys were used to assess clinical outcomes. Mann-Whitney U tests were used to assess nonnormally distributed data while χ 2 and Fisher exact tests were used to analyze categorical variables (α = 0.05 significant). The Evans group used a larger graft size ( P lengthening. Level III, retrospective cohort study.

  10. Comprehensive behavioural analysis of Long Evans and Sprague-Dawley rats reveals differential effects of housing conditions on tests relevant to neuropsychiatric disorders.

    Directory of Open Access Journals (Sweden)

    Karly M Turner

    Full Text Available Genetic (G and environmental (E manipulations are known to alter behavioural outcomes in rodents, however many animal models of neuropsychiatric disorders only use a restricted selection of strain and housing conditions. The aim of this study was to examine GxE interactions comparing two outbred rat strains, which were housed in either standard or enriched cages. The strains selected were the albino Sprague-Dawley rat, commonly used for animal models, and the other was the pigmented Long Evans rat, which is frequently used in cognitive studies. Rats were assessed using a comprehensive behavioural test battery and included well-established tests frequently employed to examine animal models of neuropsychiatric diseases, measuring aspects of anxiety, exploration, sensorimotor gating and cognition. Selective strain and housing effects were observed on a number of tests. These included increased locomotion and reduced pre-pulse inhibition in Long Evans rats compared to Sprague Dawley rats; and rats housed in enriched cages had reduced anxiety-like behaviour compared to standard housed rats. Long Evans rats required fewer sessions than Sprague Dawley rats to learn operant tasks, including a signal detection task and reversal learning. Furthermore, Long Evans rats housed in enriched cages acquired simple operant tasks faster than standard housed Long Evans rats. Cognitive phenotypes in animal models of neuropsychiatric disorders would benefit from using strain and housing conditions where there is greater potential for both enhancement and deficits in performance.

  11. Global Culture, Island Identity: Continuity and Change in the Afro-Caribbean Community of Nevis by Karen Fog Olwig

    OpenAIRE

    Maurer, WM

    1995-01-01

    This important book sheds light on the interplay of hierarchy and equality, the local and the global, and the Caribbean and the European in the cultural history of Nevis. In addition to bringing recent theoretical concerns with transnationalism and identity to Caribbean studies, Karen Olwig directs Caribbean ethnology away from static conceptions of kinship and household, religion and social life, and African cultural retentions, and toward an integration of kinship, gender,...

  12. S-Allyl cysteine improves nonalcoholic fatty liver disease in type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats via regulation of hepatic lipogenesis and glucose metabolism

    OpenAIRE

    Takemura, Shigekazu; Minamiyama, Yukiko; Kodai, Shintaro; Shinkawa, Hiroji; Tsukioka, Takuma; Okada, Shigeru; Azuma, Hideki; Kubo, Shoji

    2013-01-01

    It is important to prevent and improve diabetes mellitus and its complications in a safe and low-cost manner. S-Allyl cysteine, an aged garlic extract with antioxidant activity, was investigated to determine whether S-allyl cysteine can improve type 2 diabetes in Otsuka Long-Evans Tokushima Fatty rats with nonalcoholic fatty liver disease. Male Otsuka Long-Evans Tokushima Fatty rats and age-matched Long-Evans Tokushima Otsuka rats were used and were divided into two groups at 29 weeks of age....

  13. Measurement of the increase in the capillary permeability in skin with Evans blue labelled with iodine-125 or 131

    International Nuclear Information System (INIS)

    Sugarava, S.; Goncalves, J.M.

    1976-01-01

    The quantitative evaluation of bradykinin and histamine with Evans blue labelled with iodine -125 or 131 is described. The activity upon vascular permeability was performed in the abdominal wall of rats injecting intravenously solution of labelled Evans blue and 0,1 ml of vasoactive drugs solution intradermally. Skin discs were cut with circular punch for external counting, quantitative results being compared with control discs. By using this method, satisfactory log dose-reponse curves were obtained for bradykinin and histamine that followed the general trend of S - shaped curves [pt

  14. On the behavior of Brønsted-Evans-Polanyi relations for transition metal oxides

    DEFF Research Database (Denmark)

    Vojvodic, Aleksandra; Vallejo, Federico Calle; Guo, Wei

    2011-01-01

    Versatile Brønsted-Evans-Polanyi (BEP) relations are found from density functional theory for a wide range of transition metal oxides including rutiles and perovskites. For oxides, the relation depends on the type of oxide, the active site, and the dissociating molecule. The slope of the BEP...

  15. Feasibility of Implementation of a Parenting Intervention with Karen Refugees Resettled from Burma.

    Science.gov (United States)

    Ballard, Jaime; Wieling, Elizabeth; Forgatch, Marion

    2018-04-01

    Parents and children exposed to war and relocation have high rates of negative relational and mental health outcomes. This study tested the feasibility of implementing an adapted evidence-based parenting intervention for contexts of trauma and relocation stress. Eleven Karen refugee caregivers from Burma participated in the intervention. Participants and a focal child completed ethnographic interviews as well as structured assessments at baseline and follow-up. Caregivers reported changes in their teaching, directions, emotional regulation, discipline, and child compliance. Children reported changes in these areas and in positive parent involvement. Caregivers reported higher mental health distress immediately after the intervention, potentially due to increased awareness. Researchers made personalized referrals for counseling services as needed. Children reported a decrease in mental health symptoms. © 2017 American Association for Marriage and Family Therapy.

  16. Autoimmune hemolytic anemia, as part of Evans' syndrome, caused by cold reactive IgG autoantibodies

    NARCIS (Netherlands)

    Jaarsma, AS; Muis, N; DeGraaf, SSN

    1996-01-01

    We describe a boy with Evans' syndrome, consisting of immune thrombocytopenic purpura at age 2 and autoimmune hemolytic anemia (AIHA) at age 4. AIHA was caused by cold Ige autoantibodies. This is unusual because AIHA is generally associated with either warm IgG antibodies or cold IgM antibodies.

  17. Plasma volume methodology: Evans blue, hemoglobin-hematocrit, and mass density transformations

    Science.gov (United States)

    Greenleaf, J. E.; Hinghofer-Szalkay, H.

    1985-01-01

    Methods for measuring absolute levels and changes in plasma volume are presented along with derivations of pertinent equations. Reduction in variability of the Evans blue dye dilution technique using chromatographic column purification suggests that the day-to-day variability in the plasma volume in humans is less than + or - 20 m1. Mass density determination using the mechanical-oscillator technique provides a method for measuring vascular fluid shifts continuously for assessing the density of the filtrate, and for quantifying movements of protein across microvascular walls. Equations for the calculation of volume and density of shifted fluid are presented.

  18. 76 FR 7832 - Evans Solutions, LLC; Notice of Declaration of Intention and Soliciting Comments, Protests, and...

    Science.gov (United States)

    2011-02-11

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. DI10-20-000] Evans Solutions... original and seven copies should be filed with: Secretary, Federal Energy Regulatory Commission, 888 First...-acre man-made lake; (2) a powerhouse containing two 5-MW turbines and twelve 5-MW generators; (3) a...

  19. Only One? The Default Interventionist Perspective as a Unimodel-Commentary on Evans & Stanovich (2013).

    Science.gov (United States)

    Kruglanski, Arie W

    2013-05-01

    Evans and Stanovich (2013, this issue) defend the dual-processing theories of higher cognition after first criticizing them on fundamental grounds. To make that possible, they resurrect the very distinctions between the two alleged "types" of processing that they formerly had rejected. At the end, however, the default-interventionist model they embrace, seems similar to the single-process unimodel they contest. © The Author(s) 2013.

  20. Moniliophthora roreri (Cif y Par) Evans et al. en el cultivo de cacao

    OpenAIRE

    Sánchez Mora, Fernando David; Garcés Fiallos, Felipe Rafael

    2012-01-01

    More than a century, cacao (Theobroma cacao L.) in Ecuador has been an important source of income for farmers and currency for the country, becoming one of the biggest exporters worldwide. Then, gradually lost that status due to the attack of diseases, including moniliasis caused by [Moniliophthora roreri (Cif and Par) Evans et al.]. It can cause damage of up to 80% in production. Currently there is little scientific date information on its occurrence, symptoms, etiology, epidemiology, life c...

  1. The Armenian minister for trade and economic development Karen Chshmaritian, visited CERN on 4 July and toured the ATLAS experimental cavern and assembly hall

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Armenian Minister for Trade and Economic Development, K. Chshmaritian third from right with from left to right : Aram Kotzinian, JINR, Dubna; Dr Marzio Nessi, ATLAS, Zohrad Mnatsakanian, Ambassador at the Permanent Mission of the Republic of Armenia in Geneva, Karen Chshmaritian, Armenian Minister for Trade and Economic Development, Alexey Sissakian, Vice-Director of JINR and Peter Jenni, ATLAS Spokesperson.

  2. Assis, Machado de. Ressurrection by Machado de Assis. Trad. Karen Sherwood Sotelino. Pittsburgh: Latin American Literary Review Press, 2013. 162 p.

    Directory of Open Access Journals (Sweden)

    Cynthia Beatrice Costa

    2015-12-01

    Full Text Available Resenha crítica da primeira e única tradução para o inglês do romance machadiano Ressurreição, publicado em 1872. Lançada em 2013, a tradução da professora da Universidade de Stanford Karen Sherwood Sotelino chamou a atenção de estudiosos de Machado por mostrar como a obra do autor brasileiro desperta interesse atual no mundo anglófono.

  3. Partial splenic embolization combined with vincristine infusion for the treatment of refractory idiopathic thrombocytopenic purpura and Evans syndrome: observation of its long-term efficacy

    International Nuclear Information System (INIS)

    Chen Shibing

    2011-01-01

    Objective: To observe the long-term efficacy of partial spleen embolization combined with vincristine infusion in treating refractory idiopathic thrombocytopenic purpura (ITP) and Evans syndrome. Methods: During the period of 2000-2007, partial spleen embolization together with vincristine infusion was carried out in 30 patients with refractory idiopathic thrombocytopenic purpura (n=24) or Evans syndrome (n=6). Vincristine infusion (2 mg) via splenic artery was performed before partial spleen embolization procedure. The long-term effectiveness was observed and analyzed. Results: One week after the treatment, the platelet count was increased from preoperative (10.23±8.28) × 10 9 /L to (140.28±85.45) × 10 9 /L in patients with ITP, while the platelet count was increased from preoperative (12±8) × 10 9 /L to (210±60) × 10 9 /L in patients with Evans syndrome. Meanwhile, the hemoglobin level showed an increase in different degrees, from preoperative (63.00±13.62) g/L to postoperative (123.00±13.14) g/L. The therapeutic effectiveness was 100%. During the follow-up time lasting for 3-5 years, recurrence was seen in 11 patients (36.7%) and the overall efficacy rate was 63.3%. Conclusion: For the treatment of refractory idiopathic thrombocytopenic purpura and Evans syndrome, partial spleen embolization combined with vincristine infusion carries reliable long-term efficacy. (author)

  4. Minimum wage effects on employment and school enrollment: reply to Evans and Turner

    OpenAIRE

    David Neumark; William L. Wascher

    1996-01-01

    In earlier work, we presented results suggesting that minimum wage increases have important consequences for both the employment opportunities of youths and their decision to enroll in school. In this paper, we show that the recent claim made by William Evans and Mark Turner that our results are sensitive to changes in the definition of the enrollment rate is based upon an analysis that uses a mismeasured minimum wage index. When the data are constructed properly, our original conclusions are...

  5. Sulfonato-imino copper(ii) complexes: fast and general Chan-Evans-Lam coupling of amines and anilines.

    Science.gov (United States)

    Hardouin Duparc, V; Schaper, F

    2017-10-14

    Sulfonato-imine copper complexes with either chloride or triflate counteranions were prepared in a one-step reaction followed by anion-exchange. They are highly active in Chan-Evans-Lam couplings under mild conditions with a variety of amines or anilines, in particular with sterically hindered substrates. No optimization of reaction conditions other than time and/or temperature is required.

  6. High contrast high intensity petawatt J-KAREN-P laser facility at QST

    Science.gov (United States)

    Nishiuchi, Mamiko; Kiriyama, Hiromitsu; Sakaki, Hironao; Dover, Nicholas P.; Kondo, Kotaro; Pirozhkov, Alexander S.; Sagisaka, Akito; Fukuda, Yuji; Nishitani, Keita; Miyahara, Takumi; Ogura, Koichi; Alkhimova, Mariya A.; Pikuz, Tatiana A.; Faenov, Anatoly Y.; Watanabe, Yukinobu; Koga, James; Bulanov, Sergei V.; Kando, Masaki; Kondo, Kiminori

    2017-05-01

    We report on the J-KAREN-P laser facility at QST, which can provide PW peak power at 0.1 Hz on target. The system can deliver short pulses with an energy of 30 J and pulse duration of 30 fs after compression with a contrast level of better than 1012. Such performance in high field science will give rise to the birth of new applications and breakthroughs, which include relativistic particle acceleration, bright x-ray source generation, and nuclear activation. The current achieved laser intensity on target is up to > 9x1021 Wcm-2 with an energy of 9 J on target. The interaction with a 3 to 5- μm stainless steel tape target provides us electrons with a typical temperature of more than 10 MeV and energetic proton beams with typical maximum energies of > 40 MeV with good reproducibility. The protons are accelerated in the Target Normal Sheath Acceleration regime, which is suitable for many applications including as an injector into a beamline for medical use, which is one of our objectives.

  7. Antimalarial efficacy of nine medicinal plants traditionally used by the Karens of Andaman and Nicobar Islands, India

    Directory of Open Access Journals (Sweden)

    M. Punnam Chander

    2016-03-01

    Full Text Available The aim of this study was to assess the antimalarial activity of nine medicinal plants used by Karens of Andaman and Nicobar Islands, against Plasmodium falciparum chloroquine-sensitive MRC-2 isolate. The methanol extracts were obtained by cold percolation method and in vitro antimalarial activity was assessed using M-III method. The results indicated that out of nine plant species tested, four plants, viz., Z. spectabilis, S. wallichiana, C. pulcherrima and Amomum sp. demonstrated significant antimalarial activity (50% inhibitory concentration values were 5.5 ± 0.7, 12.0 ± 2.5, 14.6 ± 1.3 and 37.3 ± 2.5 μg/mL respectively with no toxicity effect on erythrocytes.

  8. Jan Fook: Social Work: Critical Theory and Practice & Karen Healy: Social Work Practices: Contemporary Perspectives on Change

    Directory of Open Access Journals (Sweden)

    2003-11-01

    Full Text Available In his recent book on the contemporary politics of social work, Powell (2001 nominates Jan Fook and Karen Healy as two Australian authors who have made significant contributions to the radical or critical social work tradition. I have chosen to review them together, as each, in different ways, attempts to achieve the same purpose. That is, they attempt to provide a convincing account for adopting a critical approach to practice in the contemporary conditions of the 21st century and, in doing so, re-invigorate the radical tradition of social work practice. My first comment, important for the readership of this international journal, is that both books easily 'travel' beyond the Australian context.

  9. Strain-dependent effects of acute caffeine on anxiety-related behavior in PVG/c, Long-Evans and Wistar rats.

    Science.gov (United States)

    Hughes, Robert N; Hancock, Nicola J

    2016-01-01

    To assess the possibility that acute caffeine's behavioral action might depend on rats' strain, effects of 50mg/kg of the drug were observed on activity, anxiety-related behavior and habituation learning in male and female rats from three different strains, namely PVG/c, Long-Evans and Wistar. All subjects were tested in an open field, an elevated plus maze and a light-dark box. For the three strains combined, increased occupancy of the center of the open field and entries of the open plus-maze arms with caffeine suggested caffeine-induced anxiolysis, whereas increased grooming in the open field, decreased rearing in the plus maze and increased risk assessment in the light-dark box were consistent with anxiogenesis. Caffeine also reduced open-field rearing only for PVG/c rats, and entries into and occupation of the light side of the light-dark box only for Long-Evans rats, and increased total defecation in the three types of apparatus for all three strains combined. Overall, caffeine appeared to be mainly anxiogenic. The drug also increased open-field ambulation for PVG/c rats and walking for all rats, but decreased open-field ambulation and entries into the plus maze closed arms for Wistar rats alone. In general, Wistar rats appeared to be the least and Long-Evans the most anxious of the three strains investigated. Caffeine also decreased within-session habituation of open-field ambulation for PVG/c rats alone, thereby suggesting strain-dependent interference with non-associative learning and short-term memory. Several overall sex differences were also observed that supported female rats being more active and less anxious than males. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Is cardiac resynchronization therapy an option in heart failure patients with preserved ejection fraction? Justification for the ongoing KaRen project.

    Science.gov (United States)

    Donal, Erwan; Lund, Lars; Linde, Cecilia; Daubert, Jean-Claude

    2010-01-01

    The relevance of electrical and mechanical dyssynchrony has been demonstrated in heart failure with reduced ejection fraction. Preserved ejection fraction is present in as many as 50% of patients with chronic heart failure. Recent small studies suggest that both electrical and mechanical left ventricular dyssynchrony are sometimes present in patients with heart failure and preserved ejection fraction (HFPEF). These data remain controversial and a robust validation of this hypothesis has to be achieved. In the present paper, we review in detail the concepts and try to justify the ongoing KaRen registry. This is a prospective, multicentre, international, observational study to characterize the prevalence of electrical or mechanical dyssynchrony in HFPEF and the resultant effect on prognosis. Patients are enrolled currently at the time of an acute congestive episode. The diagnosis of HFPEF is made according to clinical data, natriuretic peptides and echocardiography for the measurement of ejection fraction. Once stabilized, patients return for a hospital check-up. They undergo clinical and biological evaluation, electrocardiography and Doppler echocardiography. Thereafter, patients are followed every six months, for at least 18 months for mortality, and heart failure-related and non-cardiovascular hospitalizations. KaRen aims to characterize electrical and mechanical dyssynchrony and to assess its prognostic impact in HFPEF. The results may improve our understanding of HFPEF and generate answers to the question of whether or not dyssynchrony could be a target for cardiac resynchronization therapy in HFPEF. Copyright 2010 Elsevier Masson SAS. All rights reserved.

  11. Alpha-lipoic acid attenuates cardiac fibrosis in Otsuka Long-Evans Tokushima Fatty rats

    Directory of Open Access Journals (Sweden)

    Lee Jung Eun

    2012-09-01

    Full Text Available Abstract Background Hyperglycemia leads to cardiac oxidative stress and an imbalance in glucose homeostasis. Diabetic cardiomyopathy is characterised by cardiac hypertrophy and fibrosis. However, the underlying mechanisms of diabetic cardiomyopathy are not fully understood. This study aimed to investigate the effects of alpha-lipoic acid (ALA on cardiac energy metabolism, antioxidant effect, and fibrosis in the hearts of Otsuka Long-Evans Tokushima fatty (OLETF rats. Methods Animals were separated into non-diabetic Long-Evans Tokushima Otsuka (LETO rats and diabetes-prone OLETF rats with or without ALA (200 mg/kg/day administration for 16 weeks. Diabetic cardiomyopathy was assessed by staining with Sirius Red. The effect of ALA on AMPK signalling, antioxidant enzymes, and fibrosis-related genes in the heart of OLETF rats were performed by Western blot analysis or immunohistochemistry. Results Western blot analysis showed that cardiac adenosine monophosphate-activated kinase (AMPK signalling was lower in OLETF rats than in LETO rats, and that ALA treatment increased the signalling in OLETF rats. Furthermore, the low antioxidant activity in OLETF rats was increased by ALA treatment. In addition to increased Sirius red staining of collagen deposits, transforming growth factor-β1 (TGF-β1 and connective tissue growth factor (CTGF were expressed at higher levels in OLETF rat hearts than in LETO rat hearts, and the levels of these factors were decreased by ALA. Conclusions ALA enhances AMPK signalling, antioxidant, and antifibrogenic effect. Theses findings suggest that ALA may have beneficial effects in the treatment of diabetic cardiomyopathy.

  12. Piloting community-based medical care for survivors of sexual assault in conflict-affected Karen State of eastern Burma.

    Science.gov (United States)

    Tanabe, Mihoko; Robinson, Keely; Lee, Catherine I; Leigh, Jen A; Htoo, Eh May; Integer, Naw; Krause, Sandra K

    2013-05-21

    Given the challenges to ensuring facility-based care in conflict settings, the Women's Refugee Commission and partners have been pursuing a community-based approach to providing medical care to survivors of sexual assault in Karen State, eastern Burma. This new model translates the 2004 World Health Organization's Clinical Management of Rape Survivors facility-based protocol to the community level through empowering community health workers to provide post-rape care. The aim of this innovative study is to examine the safety and feasibility of community-based medical care for survivors of sexual assault to contribute to building an evidence base on alternative models of care in humanitarian settings. A process evaluation was implemented from July-October 2011 to gather qualitative feedback from trained community health workers, traditional birth attendants, and community members. Two focus group discussions were conducted among the highest cadre health care workers from the pilot and non-pilot sites. In Karen State, eight focus group discussions were convened among traditional birth attendants and 10 among women and men of reproductive age. Qualitative feedback contributed to an understanding of the model's feasibility. Pilot site community health workers showed interest in providing community-based care for survivors of sexual assault. Traditional birth attendants attested to the importance of making this care available. Community health workers were deeply aware of the need to maintain confidentiality and offer compassionate care. They did not raise safety as an excess concern in the provision of treatment. Data speak to the promising "feasibility" of community-based post-rape care. More time, awareness-raising, and a larger catchment population are necessary to answer the safety perspective. The pilot is an attempt to translate facility-based protocol to the community level to offer solutions for settings where traditional methods of post-rape care are not

  13. Assis, Machado de. Ressurrection by Machado de Assis. Trad. Karen Sherwood Sotelino. Pittsburgh: Latin American Literary Review Press, 2013. 162 p.

    Directory of Open Access Journals (Sweden)

    Cynthia Beatrice Costa

    2015-05-01

    Full Text Available http://dx.doi.org/10.5007/2175-7968.2015v35n2p494 Resenha crítica da primeira e única tradução para o inglês do romance machadiano Ressurreição, publicado em 1872. Lançada em 2013, a tradução da professora da Universidade de Stanford Karen Sherwood Sotelino chamou a atenção de estudiosos de Machado por mostrar como a obra do autor brasileiro desperta interesse atual no mundo anglófono.

  14. Genetic recombination at the human RH locus: A family study of the red-cell Evans phenotype reveals a transfer of exons 2-6 from the RHD to the RHCE gene

    Energy Technology Data Exchange (ETDEWEB)

    Huang, C.H.; Chen, Y.; Reid, M. [Lindsley F. Kimball Research Inst., New York, NY (United States); Ghosh, S.

    1996-10-01

    The human RH locus appears to consist of two structural genes, D and CE, which map on the short arm p34-36 of chromosome 1 and specify a most complex system of blood-group genetic polymorphisms. Here we describe a family study of the Evans (also known as {open_quotes}D..{open_quotes}) phenotype, a codominant trait associated with both qualitative and quantitative changes in D-antigen expression. A cataract-causing mutation was also inherited in this family and was apparently cotransmitted with Evans, suggesting a chromosomal linkage of these two otherwise unrelated traits. Southern blot analysis and allele-specific PCR showed the linkage of Evans with a SphI RFLP marker and the presence of a hybrid gene in the RH locus. To delineate the pattern of gene expression, the composition and structure of Rh-polypeptide transcripts were characterized by reverse transcriptase-PCR and nucleotide sequencing. This resulted in the identification of a novel Rh transcript expressed only in the Evans-positive erythroid cells. Sequence analysis showed that the transcript maintained a normal open reading frame but occurred as a CE-D-CE composite in which exons 2-6 of the CE gene were replaced by the homologous counterpart of the D gene. This hybrid gene was predicted to encode a CE-D-CE fusion protein whose surface expression correlates with the Evans phenotype. The mode and consequence of such a recombination event suggest the occurrence, in the RH locus, of a segmental DNA transfer via the mechanism of gene conversion. 31 refs., 6 figs., 1 tab.

  15. Neonatal familial Evans syndrome associated with joint hypermobility and mitral valve regurgitation in three siblings in a Saudi Arab family

    International Nuclear Information System (INIS)

    Ahmed, Fathelrahman E.; AlBakrah, Mohameed S.

    2009-01-01

    The occurrence of autoimmune hemolytic anemia and immune thrombocytopenia in the absence of a known underlying cause led to the diagnosis of Evans syndrome in a 9 month old male. Subsequently, a similar diagnosis was made in two siblings (a 3 year old boy and a 1 day old girl). The 9 month old had a chronic course with exacerbations. He was treated with steroids, intravenous immunoglobulin and colchiccine with a variable response. He died of congestive heart failure at the age of 8 years. The brother's disease course was one of remission and exacerbation. With time, remissions were prolonged and paralleled an improvement in joint hypermobility. The sister died of sepsis after a chronic course with severe exacerbattions. Only two families with Evans syndrome have been reported in the English medical literature. In one report (in a Saudi Arab family), the disease was associated with hereditary spastic paraplegia. (author)

  16. Separation of Evans and Hiro currents in VDE of tokamak plasma

    Science.gov (United States)

    Galkin, Sergei A.; Svidzinski, V. A.; Zakharov, L. E.

    2014-10-01

    Progress on the Disruption Simulation Code (DSC-3D) development and benchmarking will be presented. The DSC-3D is one-fluid nonlinear time-dependent MHD code, which utilizes fully 3D toroidal geometry for the first wall, pure vacuum and plasma itself, with adaptation to the moving plasma boundary and accurate resolution of the plasma surface current. Suppression of fast magnetosonic scale by the plasma inertia neglecting will be demonstrated. Due to code adaptive nature, self-consistent plasma surface current modeling during non-linear dynamics of the Vertical Displacement Event (VDE) is accurately provided. Separation of the plasma surface current on Evans and Hiro currents during simulation of fully developed VDE, then the plasma touches in-vessel tiles, will be discussed. Work is supported by the US DOE SBIR Grant # DE-SC0004487.

  17. Review of Financial Intelligence for Entrepreneurs: What You Really Need to Know about the Numbers by Karen Berman and Joe Knight, with John Case

    OpenAIRE

    H.L. Vacher

    2014-01-01

    Berman, Karen and Knight, Joe, with John Case. Financial Intelligence for Entrepreneurs: What You Really Need to Know about the Numbers, (Boston MA: Harvard Business Press, 2008). 285 pp. ISBN 978-1-4221-1915-0. From “The art of finance (and why it matters)” (Part One) through “Creating a financially intelligent company” (Part Eight), Financial Intelligence for Entrepreneurs is an engaging explanation and appreciation of financial statements and financial ratios. Short, easily digested cha...

  18. Moniliophthora roreri (Cif y Par Evans et al. in the crop of cocoa

    Directory of Open Access Journals (Sweden)

    Fernando David Sánchez Mora

    2012-09-01

    Full Text Available More than a century, cacao (Theobroma cacao L. in Ecuador has been an important source of income for farmers and currency for the country, becoming one of the biggest exporters worldwide. Then, gradually lost that status due to the attack of diseases, including moniliasis caused by [Moniliophthora roreri (Cif and Par Evans et al.]. It can cause damage of up to 80% in production. Currently there is little scientific date information on its occurrence, symptoms, etiology, epidemiology, life cycle management or control strategies of that disease, by performing this review both these important topics, bringing with it to this area of knowledge.

  19. The avian community of the Karen Mogensen Reserve, a wealth of biodiversity within the poorly investigated and threatened environments of northwestern Costa Rica.

    Science.gov (United States)

    Zotto, Matteo Dal; Romeo, Giuseppe; Aguilar, Luis A Mena; Sonetti, Dario; Pederzoli, Aurora

    2017-01-01

    Despite being characterized by some of the most threatened forest ecosystems of Mesoamerica, the Nicoya Peninsula is among the least known regions of neotropical Costa Rica in terms of its birdlife. Within this region, in the framework of an ongoing international cooperation program between Italy and Costa Rica, we had the opportunity to investigate the Karen Mogensen Reserve, a protected area distinguished by the presence of a variety of habitats, including tropical dry forest and moist forest. Species richness in the Reserve was relatively high compared with similar areas in northwestern Costa Rica. A series of surveys carried out over a 20-year period documented an avian community consisting of 207 species, of which 115 were breeding in the zone and another 14 were potentially breeding. We recorded five IUCN globally Vulnerable or Near-Threatened species, along with six species reported for the first time from the Nicoya Peninsula, each representing range extension of more than 100 km. Twenty-six species, mostly breeding in the area, are at their southernmost range borders, and are likely susceptible to global environmental alterations, such as the effects of climate change. Furthermore, our study revealed the presence of two species endemic to a restricted area of Central America and four subspecies endemic to Costa Rica, along with breeding populations of two species that are geographically isolated from the main ones. The present analysis led to the ecological characterization of the resident avian community, showing that 65% of the species are strictly associated with forested environments, and especially with the understory or middle tree level, hence more vulnerable to environmental change (climatic, anthropogenic, etc.) and susceptible to local extinction. These results underscore the importance of the Karen Mogensen Reserve for bird conservation within a vulnerable environmental context, and warrant the continuation of periodic bird surveys, taxonomic

  20. Mozart K.448 attenuates spontaneous absence seizure and related high-voltage rhythmic spike discharges in Long Evans rats.

    Science.gov (United States)

    Lin, Lung-Chang; Juan, Chun-Ting; Chang, Hsueh-Wen; Chiang, Ching-Tai; Wei, Ruey-Chang; Lee, Mei-Wen; Mok, Hin-Kiu; Yang, Rei-Cheng

    2013-05-01

    Recent research has revealed more evidence supporting the positive effects of music on humans and animals. However, evidence of music's effects on improving epilepsy in animals is sparse. This study aimed to clarify the influence of Mozart's music in Long Evans rats, which are characterized by spontaneous absence epilepsy (SAE) and high-voltage rhythmic spike (HVRS) discharges. Continuous electroencephalograms comprised of HVRS discharges, and behavioral performance were recorded in Long Evans rats (n=5) before, during, and after exposure to the Mozart's Sonata for Two Pianos in D Major, K.448 (Mozart K.448). The same evaluation was repeated after they had been subjected to daily exposure of the music for 20 days. Seizure frequencies and spontaneous HVRS discharges were reduced in all of the SAE rats during and after music exposure compared with the pre-music stage. The average seizure frequencies were 79.8±24.6, 48±15.2, and 33±12.1/h before, during, and after music exposure, respectively. The average run of spike episodes were 84.6±18.4, 52±17.8, and 36.8±16.9/h before, during, and after music exposure, respectively. The seizure frequencies and related run of spike episodes decreased by 39.8% and 38.5% during, and 58.6% and 56.6% post music exposure, respectively. The average run of spike durations and spike numbers also showed significant decreases (reduction by 47.1%, 47.8% during music and 60.8%, 61.3% post music). After daily music exposure for 20 days, the number of HVRS discharges and seizure frequencies during and after music exposure, however, showed no further accumulative reduction or adaptation effect. These results suggest that Mozart K.448 had a positive short-term effect in attenuating the spontaneous HVRS discharges in Long Evans rats. However, the mechanism needs further investigation. Copyright © 2013 Elsevier B.V. All rights reserved.

  1. Hydrology, microbiology and carbon cycling at a high Arctic polythermal glacier, (John Evans Glacier, Ellesmere Island, Canada)

    Science.gov (United States)

    Skidmore, Mark Leslie

    Analysis of the hydrology, hydrochemistry and microbiology at polythermal John Evans Glacier and geochemical and isotopic data from Haut Glacier d'Arolla demonstrates that certain subglacial chemical weathering processes are microbially mediated. Subglacial drainage is likely an annual occurrence beneath John Evans Glacier and solute rich subglacial waters indicate over winter storage at the glacier bed. Subglacial microbial populations are also present, and are viable under simulated near in situ conditions at 0.3°C. This suggests that temperate subglacial environments at a polythermal glacier, which are isolated by cold ice above and around them, provide a viable habitat for life where basal water and organic carbon are present throughout the year. Thus, a subglacial microbial ecosystem based upon legacy carbon, (from old soils or surface inputs) rather than primary production may exist, where redox processes are a key component, and seasonal anoxia may occur. The existence of anoxic environments is supported by the presence of strictly anaerobic bacteria (sulphate reducing bacteria and methanogens) in the basal sediments---which are viable in culture at 4°C---and also argues that these bacteria are not washed in with oxygenated surface meltwaters, but are present in the subglacial environment. During the summer meltseason there is a large input of surficial waters to the subglacial system and water residence times are drastically reduced. Hence, kinetic weathering processes dominate, resulting in light delta 13C-DIC (dissolved inorganic carbon) in glacial runoff, as verified by experimental work on CaCO3 and John Evans Glacier sediments. The experiments demonstrate kinetic bedrock fractionation (KBF) during carbonate hydrolysis and that kinetic fractionation of CO2 (KFC) is proportional to the rate of CO2 draw down during the carbonation of carbonates. This results in significantly depleted delta13C-DIC values (≤-16 ‰) relative to the bedrock carbonate

  2. We favor formal models of heuristics rather than lists of loose dichotomies: a reply to Evans and Over

    Science.gov (United States)

    Gigerenzer, Gerd

    2009-01-01

    In their comment on Marewski et al. (good judgments do not require complex cognition, 2009) Evans and Over (heuristic thinking and human intelligence: a commentary on Marewski, Gaissmaier and Gigerenzer, 2009) conjectured that heuristics can often lead to biases and are not error free. This is a most surprising critique. The computational models of heuristics we have tested allow for quantitative predictions of how many errors a given heuristic will make, and we and others have measured the amount of error by analysis, computer simulation, and experiment. This is clear progress over simply giving heuristics labels, such as availability, that do not allow for quantitative comparisons of errors. Evans and Over argue that the reason people rely on heuristics is the accuracy-effort trade-off. However, the comparison between heuristics and more effortful strategies, such as multiple regression, has shown that there are many situations in which a heuristic is more accurate with less effort. Finally, we do not see how the fast and frugal heuristics program could benefit from a dual-process framework unless the dual-process framework is made more precise. Instead, the dual-process framework could benefit if its two “black boxes” (Type 1 and Type 2 processes) were substituted by computational models of both heuristics and other processes. PMID:19784854

  3. Perceptions of nursing care quality, in acute hospital settings measured by the Karen instruments.

    Science.gov (United States)

    Andersson, Inger S; Lindgren, Margareta

    2013-01-01

    The objectives of this study were to measure the quality of nursing care from the perspectives of patients and personnel and to compare these perspectives. The perception of quality in nursing care is affected by patient needs and it is common that patients and personnel disagree on the nature of the quality. Thus, it is important to measure the quality from both perspectives. A total of 95 patients and 120 personnel from surgical and medical wards at a hospital in Sweden participated. The Karen instruments were used for data collection. A scale index was used for comparison of the perspectives. The patients and personnel were satisfied with the quality of care and there were no obvious differences in the total index. The different subscales indicated areas of lower care quality in need of improvement. The quality of the care seemed to be satisfactory from the perspectives of both the patients and the personal. Further analysis from the subscale or a variable level is needed to define areas of lower care quality. Measurements have to be carried out continuously to guarantee care quality over time, as a result of organisational changes and financial cutbacks. © 2012 Blackwell Publishing Ltd.

  4. Modeling Ethanol Decomposition on Transition Metals: A Combined Application of Scaling and Bronsted-Evans-Polanyi Relations

    DEFF Research Database (Denmark)

    Ferrin, P.; Simonetti, D.; Kandoi, S.

    2009-01-01

    calculations necessary to describe trends in activity and selectivity across metal and alloy surfaces, thus extending the reach of DFT to more complex systems. In-this work, the well-known family of Bronsted-Evans-Polanyi (BEP) correlations, connecting minima with maxima in the potential energy surface...... on a subset of these surfaces are calculated. Experiments on supported catalysts verify that this simple model is reasonably accurate in describing reactivity trends across metals, suggesting that the combination of BEP and scaling relations may substantially reduce the cost of DFT calculations required...

  5. Baseline characteristics of patients with heart failure and preserved ejection fraction included in the Karolinska Rennes (KaRen) study.

    Science.gov (United States)

    Donal, Erwan; Lund, Lars H; Oger, Emmanuel; Hage, Camilla; Persson, Hans; Reynaud, Amélie; Ennezat, Pierre-Vladimir; Bauer, Fabrice; Sportouch-Dukhan, Catherine; Drouet, Elodie; Daubert, Jean-Claude; Linde, Cecilia

    2014-02-01

    Karolinska Rennes (KaRen) is a prospective observational study to characterize heart failure patients with preserved ejection fraction (HFpEF) and to identify prognostic factors for long-term mortality and morbidity. To report characteristics and echocardiography at entry and after 4-8 weeks of follow-up. Patients were included following an acute heart failure presentation with B-type natriuretic peptide (BNP)>100 ng/L or N-terminal pro-BNP (NT-proBNP)>300 ng/L and left ventricular ejection fraction (LVEF)>45%. The mean ± SD age of 539 included patients was 77 ± 9 years and 56% were women. Patient history included hypertension (78%), atrial tachyarrhythmia (44%), prior heart failure (40%) and anemia (37%), but left bundle branch block was rare (3.8%). Median NT-proBNP was 2448 ng/L (n=438), and median BNP 429 ng/L (n=101). Overall, 101 patients did not return for the follow-up visit, including 13 patients who died (2.4%). Apart from older age (80 ± 9 vs. 76 ± 9 years; P=0.006), there were no significant differences in baseline characteristics between patients who did and did not return for follow-up. Mean LVEF was lower at entry than follow-up (56% vs. 62%; P<0.001). At follow-up, mean E/e' was 12.9 ± 6.1, left atrial volume index 49.4±17.8mL/m(2). Mean global left ventricular longitudinal strain was -14.6 ± 3.9%; LV mass index was 126.6 ± 36.2g/m(2). Patients in KaRen were old with slight female dominance and hypertension as the most prevalent etiological factor. LVEF was preserved, but with increased LV mass and depressed LV diastolic and longitudinal systolic functions. Few patients had signs of electrical dyssynchrony (ClinicalTrials.gov.- NCT00774709). Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  6. We favor formal models of heuristics rather than lists of loose dichotomies : A reply to Evans and Over

    OpenAIRE

    Marewski, J.; Gaissmaier, W.; Gigerenzer, G.

    2010-01-01

    In their comment on Marewski et al. (good judgments do not require complex cognition, 2009) Evans and Over (heuristic thinking and human intelligence: a commentary on Marewski, Gaissmaier and Gigerenzer, 2009) conjectured that heuristics can often lead to biases and are not error free. This is a most surprising critique. The computational models of heuristics we have tested allow for quantitative predictions of how many errors a given heuristic will make, and we and others have measured the a...

  7. Evans Syndrome Presented with Marginal Zone Lymphoma and Duodenal Neuroendocrine Tumor in an Elderly Woman

    Directory of Open Access Journals (Sweden)

    Daniele D'Ambrosio

    2016-12-01

    Full Text Available Evans syndrome (ES is an autoimmune disorder characterized by simultaneous or sequential development of autoimmune hemolytic anemia, immune thrombocytopenia, and/or neutropenia. ES can be classified as a primary (idiopathic or secondary (associated with an underlying disease syndrome. We report a case of ES in an elderly patient in the presence of multiple trigger factors such as recent influenza vaccine, marginal zone lymphoma, and neuroendocrine tumor G1. Whether this association is casual or causal remains a matter of speculation. It is however necessary to have a thorough work-up in a newly diagnosed ES and a more accurate search of miscellaneous factors especially in elderly patients.

  8. Evans syndrome with non-ST segment elevation myocardial infarction complicated by hemopericardium

    Directory of Open Access Journals (Sweden)

    Filiz Kizilirmak

    2016-09-01

    Full Text Available Evans syndrome (ES is a rare hematological disease characterized by autoimmune hemolytic anemia, immune thrombocytopenia, and/or neutropenia, all of which may be seen simultaneously or subsequently. Thrombotic events in ES are uncommon. Furthermore, non-ST segment-elevation myocardial infarction (NSTEMI during ES is a very rare condition. Here, we describe a case of a 69-year-old female patient presenting with NSTEMI and ES. Revascularization via percutaneous coronary intervention (PCI was scheduled and performed. Hemopericardium and cardiac tamponade occurred 5 h after PCI, and urgent pericardiocentesis was performed. Follow-up was uneventful, and the patient was safely discharged. Early recognition and appropriate management of NSTEMI is crucial to prevent morbidity and mortality. Coexistence of NSTEMI and ES, which is associated with increased bleeding risk, is a challenging scenario and these patients should be closely monitored in order to achieve early recognition and treatment of complications.

  9. On the behavior of Bronsted-Evans-Polanyi Relations for Transition Metal Oxides

    Energy Technology Data Exchange (ETDEWEB)

    Vojvodic, Aleksandra

    2011-08-22

    Versatile Broensted-Evans-Polanyi (BEP) relations are found from density functional theory for a wide range of transition metal oxides including rutiles and perovskites. For oxides, the relation depends on the type of oxide, the active site and the dissociating molecule. The slope of the BEP relation is strongly coupled to the adsorbate geometry in the transition state. If it is final state-like the dissociative chemisorption energy can be considered as a descriptor for the dissociation. If it is initial state-like, on the other hand, the dissociative chemisorption energy is not suitable as descriptor for the dissociation. Dissociation of molecules with strong intramolecular bonds belong to the former and molecules with weak intramolecular bonds to the latter group. We show, for the prototype system La-perovskites, that there is a 'cyclic' behavior in the transition state characteristics upon change of the active transition metal of the oxide.

  10. The future of nursing: how important is discipline-specific knowledge? A conversation with Jacqueline Fawcett. Interview by Dr. Janie Butts and Dr. Karen Rich.

    Science.gov (United States)

    Fawcett, Jacqueline

    2012-04-01

    Nurses have long attempted to secure a unique identity for the profession. Many scholars are now promoting an interdisciplinary framework for nursing practice. Fawcett is convinced that interdisciplinary practice poses a danger for nursing to lose its identity and that interdisciplinary practice cannot be successful if members of each discipline do not understand the conceptual models, practice, and research of their own discipline. Dr. Janie Butts and Dr. Karen Rich interviewed Dr. Jacqueline Fawcett about her views related to discipline-specific knowledge and nursing's future. The authors conclude that Fawcett's scientific foundation gives nursing the solidarity and power necessary to determine the unique internal goods of its practice.

  11. Changes in plasma glucose in Otsuka Long-Evans Tokushima Fatty rats after oral administration of maple syrup.

    Science.gov (United States)

    Nagai, Noriaki; Yamamoto, Tetsushi; Tanabe, Wataru; Ito, Yoshimasa; Kurabuchi, Satoshi; Mitamura, Kuniko; Taga, Atsushi

    2015-01-01

    We investigate whether maple syrup is a suitable sweetener in the management of type 2 diabetes using the Otsuka Long-Evans Tokushima Fatty (OLETF) rat. The enhancement in plasma glucose (PG) and glucose absorption in the small intestine were lower after the oral administration of maple syrup than after sucrose administration in OLETF rats, and no significant differences were observed in insulin levels. These data suggested that maple syrup might inhibit the absorption of glucose from the small intestine and preventing the enhancement of PG in OLETF rats. Therefore, maple syrup might help in the prevention of type 2 diabetes.

  12. Ocorrência simultânea de síndrome de Evans e anemia falciforme em uma criança de 2 anos Simultaneous occurrence of Evans syndrome and sickle cell anemia in a 2 year-old child

    Directory of Open Access Journals (Sweden)

    Adriana Alexandre Brito

    2012-04-01

    Full Text Available A associação entre anemia falciforme (AF e síndrome de Evans (SE parece ser rara. Esse estudo objetivou relatar o caso de uma criança com AF e SE. A paciente R. M. S. S., 2 anos de idade, foi admitida em um centro hematológico apresentando hemorragia de mucosa, leucometria 20,3 × 10(9/l, hemoglobina 4,6 g/dl e plaquetas 28 × 10(9/l. Posteriormente, realizou-se mielograma, que evidenciou hipercelularidade eritroide, sugerindo hemólise. Teste positivo da antiglobulina direcionou o diagnóstico para SE. Iniciou-se pulsoterapia com corticoide até regularização da plaquetometria. Hemácias em foice foram visualizadas no esfregaço sanguíneo; eletroforese de hemoglobina revelou fenótipo SS. A associação parece ter sido fortuita e gerou quadro grave, que deve ser reconhecido prontamente.The association of sickle cell anemia (SCA and Evans syndrome (ES seems to be uncommon. This study aimed to report a case of a child with SCA and SE. 2 year-old R. M. S. S. was admitted into a hematologic center with mucosal bleedings. Exam results revealed leucocyte 20.3 × 10(9/l, hemoglobin 4.6 g/dl, and platelets 28 × 10(9/l. Subsequently, myelogram was performed and showed erythroid-hypercellularity, which suggested hemolysis. Positive antiglobulin test corroborated the diagnosis of ES. Corticosteroid pulse therapies were conducted until normalization of platelet count. Sickle cells were detected in blood smears and hemoglobin electrophoresis revealed SS phenotype. Despite the fact the association appears to occur randomly, it causes severe clinical symptoms, which must be promptly recognized.

  13. Absence of diurnal variation in visceromotor response to colorectal distention in normal Long Evans rats [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Sara Botschuijver

    2016-01-01

    Full Text Available Background: Enhanced colorectal sensitivity (i.e. visceral hypersensitivity is thought to be a pathophysiological mechanism in irritable bowel syndrome (IBS. In healthy men a circadian variation in rectal perception to colonic distention was described. Disturbed day and night rhythms, which occur in shift work and trans meridian flights, are associated with the prevalence of IBS. This raises the question whether disruptions of circadian control are responsible for the observed pathology in IBS. Prior to investigating altered rhythmicity in relation to visceral hypersensitivity in a rat model for IBS, it is relevant to establish whether normal rats display circadian variation similar to healthy men.  Methodology and findings: In rodents colorectal distension leads to reproducible contractions of abdominal musculature. We used quantification of this so called visceromotor response (VMR by electromyography (EMG to assess visceral sensitivity in rats. We assessed the VMR in normal male Long Evans rats at different time points of the light/dark cycle. Although a control experiment with male maternal separated rats confirmed that intentionally inflicted (i.e. stress induced changes in VMR can be detected, normal male Long Evans rats showed no variation in VMR along the light/dark cycle in response to colorectal distension. Conclusions: In the absence of a daily rhythm of colorectal sensitivity in normal control rats it is not possible to investigate possible aberrancies in our rat model for IBS.

  14. Dermatomiositis y síndrome de evans asociado a infección por HTLV-1

    Directory of Open Access Journals (Sweden)

    David Loja-Oropeza

    2016-01-01

    Full Text Available Paciente mujer de 55 años de edad, natural de Ayacucho, con antecedente de dermatomiositis desde hace 3 años, recibió tratamiento irregular con prednisona. Dos meses antes del ingreso presenta anemia hemolítica autoinmune y púrpura trombocitopénica idiopática, recibió pulsos de metilprednisolona y transfusión de paquetes globulares. Al ingreso, soporosa, mal estado general, marcada pérdida ponderal, deshidratada, livedo reticularis en miembros inferiores, onicodistrofia y onicolisis múltiple en los dedos de ambos pies. Western Blot positivo para HTLV-1. Evoluciona con hipoglicemia recurrente. Reportamos un caso de dermatomiositis y síndrome de Evans presentados en el contexto de una infección por virus linfotrópico humano tipo 1.

  15. Chronic MK-801 Application in Adolescence and Early Adulthood: A Spatial Working Memory Deficit in Adult Long-Evans Rats But No Changes in the Hippocampal NMDA Receptor Subunits

    Science.gov (United States)

    Uttl, Libor; Petrasek, Tomas; Sengul, Hilal; Svojanovska, Marketa; Lobellova, Veronika; Vales, Karel; Radostova, Dominika; Tsenov, Grygoriy; Kubova, Hana; Mikulecka, Anna; Svoboda, Jan; Stuchlik, Ales

    2018-01-01

    The role of NMDA receptors in learning, memory and hippocampal function has long been recognized. Post-mortem studies have indicated that the expression or subunit composition of the NMDA glutamate receptor subtype might be related to the impaired cognitive functions found in schizophrenia patients. NMDA receptor antagonists have been used to develop animal models of this disorder. There is accumulating evidence showing that not only the acute but also the chronic application of NMDA receptor antagonists may induce schizophrenia-like alterations in behavior and brain functions. However, limited evidence is available regarding the consequences of NMDA receptor blockage during periods of adolescence and early adulthood. This study tested the hypothesis that a 2-week treatment of male Long-Evans and Wistar rats with dizocilpine (MK-801; 0.5 mg/kg daily) starting at postnatal days (PD) 30 and 60 would cause a long-term cognitive deficit and changes in the levels of NMDA receptor subunits. The working memory version of the Morris water maze (MWM) and active place avoidance with reversal on a rotating arena (Carousel) requiring cognitive coordination and flexibility probed cognitive functions and an elevated-plus maze (EPM) was used to measure anxiety-like behavior. The western blot method was used to determine changes in NMDA receptor subunit levels in the hippocampus. Our results showed no significant changes in behaviors in Wistar rats. Slightly elevated anxiety-like behavior was observed in the EPM in Long-Evans rats with the onset of treatment on PD 30. Furthermore, Long-Evans rats treated from PD 60 displayed impaired working memory in the MWM. There were; however, no significant changes in the levels of NMDA receptor subunits because of MK-801 administration. These findings suggest that a 2-week treatment starting on PD 60 in Long-Evans rats leads to long-term changes in working memory, but this deficit is not paralleled by changes in NMDA receptor subunits. These

  16. Simulations of vertical disruptions with VDE code: Hiro and Evans currents

    Science.gov (United States)

    Li, Xujing; Di Hu Team; Leonid Zakharov Team; Galkin Team

    2014-10-01

    The recently created numerical code VDE for simulations of vertical instability in tokamaks is presented. The numerical scheme uses the Tokamak MHD model, where the plasma inertia is replaced by the friction force, and an adaptive grid numerical scheme. The code reproduces well the surface currents generated at the plasma boundary by the instability. Five regimes of the vertical instability are presented: (1) Vertical instability in a given plasma shaping field without a wall; (2) The same with a wall and magnetic flux ΔΨ|plX< ΔΨ|Xwall(where X corresponds to the X-point of a separatrix); (3) The same with a wall and magnetic flux ΔΨ|plX> ΔΨ|Xwall; (4) Vertical instability without a wall with a tile surface at the plasma path; (5) The same in the presence of a wall and a tile surface. The generation of negative Hiro currents along the tile surface, predicted earlier by the theory and measured on EAST in 2012, is well-reproduced by simulations. In addition, the instability generates the force-free Evans currents at the free plasma surface. The new pattern of reconnection of the plasma with the vacuum magnetic field is discovered. This work is supported by US DoE Contract No. DE-AC02-09-CH11466.

  17. Parvovirus B19-triggered Acute Hemolytic Anemia and Thrombocytopenia in a Child with Evans Syndrome.

    Science.gov (United States)

    Zikidou, Panagiota; Grapsa, Anastassia; Bezirgiannidou, Zoe; Chatzimichael, Athanassios; Mantadakis, Elpis

    2018-01-01

    Human parvovirus B19 (HPV-B19) is the etiologic agent of erythema infectiosum, of transient aplastic crises in individuals with underlying chronic hemolytic disorders, and of chronic pure red cell aplasia in immunocompromised individuals. We describe a 14-year-old girl with long-standing Evans syndrome, who presented with severe anemia, reticulocytopenia and thrombocytopenia. A bone marrow aspirate revealed severe erythroid hypoplasia along with the presence of giant pronormoblasts, while serological studies and real-time PCR of whole blood were positive for acute parvovirus B19 infection. The patient was initially managed with corticosteroids, but both cytopenias resolved only after administration of intravenous gamma globulin 0.8g/kg. Acute parvovirus B19 infection should be suspected in patients with immunologic diseases, who present reticulocytopenic hemolytic anemia and thrombocytopenia. In this setting, intravenous gamma globulin is effective for both cytopenias.

  18. Multiple [3H]imipramine binding sites in brains of male and female Fawn-Hooded and Long-Evans rats

    International Nuclear Information System (INIS)

    Ieni, J.R.; Zukin, S.R.; Praag, H.M. van; Tobach, E.; Barr, G.A.

    1985-01-01

    Comparisons of high- and low-affinity [ 3 H]imipramine binding to whole brain homogenates from adult male and female rats of the Fawn-Hooded and Long-Evans strains were performed. Most strikingly, no significant differences were observed between the two strains in any of the binding parameters, indicating that brain [ 3 H]imipramine binding sites, which may be related to the serotonergic uptake process, appear normal in a strain of rats with serotonin platelet storage pool disease. However, a significant sex difference in high- but not low-affinity whole brain [ 3 H]imipramine Bsub(max) values was observed, with females of both strains having higher densities than males. (Auth.)

  19. Kinetic analysis of the rate of corneal wound healing in Otsuka long-evans Tokushima Fatty rats, a model of type 2 diabetes mellitus.

    Science.gov (United States)

    Nagai, Noriaki; Murao, Takatoshi; Okamoto, Norio; Ito, Yoshimasa

    2010-01-01

    Diabetic keratopathy is a well-known ocular complication secondary to type 2 diabetes mellitus. In this study, we performed a kinetic analysis of corneal wound healing in Long-Evans rats (normal rat) and Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of type 2 diabetes mellitus. Corneal wound healing in 7-week-old normal rats was mostly complete 24 h after corneal epithelial abrasion, and the process of corneal wound healing took place according to an equation with a first-order rate constant. The rate of corneal wound healing in normal rats decreased with aging. The process of corneal wound healing in 38- and 60-week-old normal and OLETF rats occurred in two phases with rate constants for the first and second phases represented as alpha and beta, respectively. The alpha and beta values in 38- and 60-week-old OLETF rats were lower than those in normal rats of the corresponding age. Furthermore, a close relationship was observed between the corneal wound healing rate constant and plasma glucose levels in OLETF rats. The present studies suggest the sequence of events that occur following damage to the corneal surface in OLETF rats as a model animal for a human type 2 diabetes mellitus.

  20. Association in Long-Evans hooded rats of red cell 2,3-diphosphoglycerate levels with hemoglobin types.

    Science.gov (United States)

    Brewer, G; Gilman, J; Noble, N; Crews, V

    1978-08-01

    Two sublines of commercially available Long-Evans hooded rats have been developed by genetic selection. These sublines have widely differing levels of erythrocyte 2,3-diphosphoglycerate (DPG) due to different alleles at a single genetic locus. In the present work, it is shown that rats from the commercial population are also polymorphic at a hemoglobin locus, probably involving two alleles of the IIIbeta-globin chain locus. Particular hemoglobin types have been found to be strongly associated with certain DPG types, not only in the high-DPG and low-DPG lines but also in the commercial population. Two explanations for this association are considered. One is a single-locus hypothesis, with hemoglobin allelic variation causing DPG variation, and the other is a two-locus hypothesis, with marked linkage disequilibrium.

  1. Household ecology and out-migration among ethnic Karen along the Thai-Myanmar border

    Directory of Open Access Journals (Sweden)

    Daniel M. Parker

    2014-04-01

    Full Text Available Background: Local migration in developing-world settings, particularly among rural populations, is an important yet understudied demographic process. Research on migration in such populations can help us test and inform anthropological and demographic theory. Furthermore, it can lead to a better understanding of modern population distributions and epidemiologic landscapes. Objective: The purpose of this study was to investigate the potential relationships between household- and individual-level factors on out-migration among Karen villagers along the Thai-Myanmar border. Methods: We used a random effects hazard model to investigate the relationship of household consumer-producer (C/P ratios, the number of household members, and an individual's sex on the odds of outmigration. We then used simulations in order to test the sensitivity of our model to our C/P ratio weighting scheme. Results: We found that the number of household members is predictive of increased out-migration. Household C/P ratios were positively associated with out-migration in children but negatively associated with out-migration in working age adults. Finally, adult males were much more likely to move out of the household than were adult females. Conclusions: While household-level factors are important with regard to out-migration, the relationships between such household-level factors and out-migration are complex and vary by the individual's age and sex. Our study offers two novel concepts to household demography and migration studies. First, this study offers a new approach to evaluating weighting schemes for C/P ratios. Second, we show that household level factors are important at units of time (two-week intervals that are not normally studied by demographers.

  2. Parvovirus B19-triggered acute hemolytic anemia and thrombocytopenia in a child with Evans syndrome

    Directory of Open Access Journals (Sweden)

    ELPIS MANTADAKIS

    2018-03-01

    Full Text Available Background: Human parvovirus B19 (HPV-B19 is the etiologic agent of erythema infectiosum, of transient aplastic crises in individuals with underlying chronic hemolytic disorders, and of chronic pure red cell aplasia in immunocompromised individuals. Case report. We describe a 14-year-old girl with long-standing Evans syndrome, who presented with severe anemia, reticulocytopenia and thromocytopenia. A bone marrow aspirate revealed severe erythroid hypoplasia along with presence of giant pronormoblasts, while serological studies and real-time PCR of whole blood were positive for acute parvovirus B19 infection. The patient was initially managed with corticosteroids, but both cytopenias resolved only after administration of intravenous gamma globulin 0.8g/kg. Conclusion: Acute parvovirus B19 infection should be suspected in patients with immunologic diseases, who present with reticulocytopenic hemolytic anemia and thrombocytopenia. In this setting, intravenous gamma globulin is effective for both cytopenias.

  3. A model for predicting skin dose received by patients from an x-ray ...

    African Journals Online (AJOL)

    We have done this by modifying a model for predicting skin dose derived by Edmonds for a triple-phase generator. Results for 100 patients based on the triple-phase generator output show a reasonable average agreement (»1%) between our present model and the Edmonds's model. Although our earlier estimated ...

  4. A Case Study: Dual-Process Theories of Higher Cognition-Commentary on Evans & Stanovich (2013).

    Science.gov (United States)

    Osman, Magda

    2013-05-01

    Dual-process theories of higher order cognition (DPTs) have been enjoying much success, particularly since Kahneman's 2002 Nobel prize address and recent book Thinking, Fast and Slow (2009). Historically, DPTs have attempted to provide a conceptual framework that helps classify and predict differences in patterns of behavior found under some circumstances and not others in a host of reasoning, judgment, and decision-making tasks. As evidence has changed and techniques for examining behavior have moved on, so too have DPTs. Killing two birds with one stone, Evans and Stanovich (2013, this issue) respond to five main criticisms of DPTs. Along with addressing each criticism in turn, they set out to clarify the essential defining characteristics that distinguish one form of higher order cognition from the other. The aim of this commentary is to consider the defining characteristics of Type 1 and Type 2 processing that have been proposed and to suggest that the evidence can be taken to support quantitative differences rather than qualitatively distinct processes. © The Author(s) 2013.

  5. ‘Historical narratives and historical desires: re-evaluating American art criticism of the mid-nineteenth century’: Karen Georgi, Critical Shift: Rereading Jarves, Cook, Stillman, and the Narratives of Nineteenth-Century American Art, The Pennsylvania State University Press, 2013

    OpenAIRE

    Emily Gephart

    2014-01-01

    Striving to distinguish their authority as and demonstrate their professionalism, art critics James Jackson Jarves, Clarence Cook, and William James Stillman wrote exhibition reviews, essays, and increasingly self-conscious histories of American art and artists in the mid-nineteenth century. Whereas their writing has often been employed to establish a model of opposed pre- and post-war periodization in American art, Karen Georgi challenges this view, re-evaluating the rhetorical structures t...

  6. 2252-IJBCS-Article-Edmond Hien

    African Journals Online (AJOL)

    hp

    . 1°30'46''W avec une altitude de 303 m). Prélèvement et préparation des échantillons de sol. Les échantillons de sol ont été prélevés dans l'horizon de surface (0-10 cm) dans un champ paysan conventionnel. (sans fertilisation chimique et ...

  7. Evans blue dye-enhanced imaging of the brain microvessels using spectral focusing coherent anti-Stokes Raman scattering microscopy.

    Directory of Open Access Journals (Sweden)

    Bo-Ram Lee

    Full Text Available We performed dye-enhanced imaging of mouse brain microvessels using spectral focusing coherent anti-Stokes Raman scattering (SF-CARS microscopy. The resonant signals from C-H stretching in forward CARS usually show high background intensity in tissues, which makes CARS imaging of microvessels difficult. In this study, epi-detection of back-scattered SF-CARS signals showed a negligible background, but the overall intensity of resonant CARS signals was too low to observe the network of brain microvessels. Therefore, Evans blue (EB dye was used as contrasting agent to enhance the back-scattered SF-CARS signals. Breakdown of brain microvessels by inducing hemorrhage in a mouse was clearly visualized using backward SF-CARS signals, following intravenous injection of EB. The improved visualization of brain microvessels with EB enhanced the sensitivity of SF-CARS, detecting not only the blood vessels themselves but their integrity as well in the brain vasculature.

  8. Rationale and design of the Karolinska-Rennes (KaRen) prospective study of dyssynchrony in heart failure with preserved ejection fraction.

    Science.gov (United States)

    Donal, Erwan; Lund, Lars H; Linde, Cecilia; Edner, Magnus; Lafitte, Stéphane; Persson, Hans; Bauer, Fabrice; Ohrvik, John; Ennezat, Pierre-Vladimir; Hage, Camilla; Löfman, Ida; Juilliere, Yves; Logeart, Damien; Derumeaux, Geneviève; Gueret, Pascal; Daubert, Jean-Claude

    2009-02-01

    Heart failure with preserved ejection fraction (HFPEF) is common but not well understood. Electrical dyssynchrony in systolic heart failure is harmful. Little is known about the prevalence and the prognostic impact of dyssynchrony in HFPEF. We have designed a prospective, multicenter, international, observational study to characterize HFPEF and to determine whether electrical or mechanical dyssynchrony affects prognosis. Patients presenting with acute heart failure (HF) will be screened so as to identify 400 patients with HFPEF. Inclusion criteria will be: acute presentation with Framingham criteria for HF, left ventricular ejection fraction>or=45%, brain natriuretic peptide (BNP)>100 pg/mL or NT-proBNP>300 pg/mL. Once stabilized, 4-8 weeks after the index presentation, patients will return and undergo questionnaires, serology, ECG, and Doppler echocardiography. Thereafter, patients will be followed for mortality and HF hospitalization every 6 months for at least 18 months. Sub-studies will focus on echocardiographic changes from the acute presentation to the stable condition and on exercise echocardiography, cardiopulmonary exercise testing, and serological markers. KaRen aims to characterize electrical and mechanical dyssynchrony and to assess its prognostic impact in HFPEF. The results might improve our understanding of HFPEF and generate answers to the question whether dyssynchrony could be a target for therapy in HFPEF.

  9. Methamphetamine use and correlates in two villages of the highland ethnic Karen minority in northern Thailand: a cross sectional study

    Directory of Open Access Journals (Sweden)

    Ono-Kihara Masako

    2009-05-01

    Full Text Available Abstract Background The prevalence of methamphetamine use and human immunodeficiency virus (HIV incidence are high in lowland Thai society. Despite increasing social and cultural mixing among residents of highland and lowland Thai societies, however, little is known about methamphetamine use among ethnic minority villagers in the highlands. Methods A cross-sectional survey examined Karen villagers from a developed and a less-developed village on February 24 and March 26, 2003 to evaluate the prevalence and social correlates of methamphetamine use in northern Thailand. Data were collected in face-to-face interviews using a structured questionnaire. Results The response rate was 79.3% (n = 548. In all, 9.9% (males 17.6%, females 1.7% of villagers reported methamphetamine use in the previous year. Methamphetamine was used mostly by males and was significantly related to primary or lower education; to ever having worked in town; to having used opium, marijuana, or heroin in the past year; and to ever having been diagnosed with a sexually transmitted infection (STI. Conclusion Since labor migration to towns is increasingly common among ethnic minorities, the prevention of methamphetamine use and of HIV/STI infection among methamphetamine users should be prioritized to prevent HIV in this minority population in Thailand.

  10. A Dose–Response Analysis of the Reproductive Effects of a Single Gestational Dose of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Male Long Evans Hooded Rat Offspring,

    OpenAIRE

    Gray, L. E.; Ostby, J. S.; Kelce, W. R.

    1997-01-01

    Male rats exposedin uteroto 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) display reduced fertility as a consequence of the direct action of TCDD on the epididymides, as well as delayed puberty and altered reproductive organ weights. The current study provides dose–response data for the reproductive effects of TCDD, administered during pregnancy, with an emphasis on the effects of TCDD on testicular, epididymal, and ejaculated sperm numbers. Long Evans Hooded rats were dosed by gavage with 0, 0....

  11. Dental Health - Multiple Languages

    Science.gov (United States)

    ... Health Resource Center Burmese (myanma bhasa) Expand Section Betel Nut - English PDF Betel Nut - myanma bhasa (Burmese) PDF Orange County North ... California Dental Association Karen (S’gaw Karen) Expand Section Betel Nut - English PDF Betel Nut - S’gaw Karen (Karen) ...

  12. Oral Cancer - Multiple Languages

    Science.gov (United States)

    ... a new window. Burmese (myanma bhasa) Expand Section Betel Nut - English PDF Betel Nut - myanma bhasa (Burmese) PDF Orange County North ... California Dental Association Karen (S’gaw Karen) Expand Section Betel Nut - English PDF Betel Nut - S’gaw Karen (Karen) ...

  13. Evans syndrome in children. Long-term outcome in a prospective French national observational cohort.

    Directory of Open Access Journals (Sweden)

    Nathalie eAladjidi

    2015-09-01

    Full Text Available Evans syndrome (ES is a rare autoimmune disorder whose long-term follow-up characteristics are unknown. Patients under 18 at the time of diagnosis of a first autoimmune cytopenia have been included since 2004 in a national prospective observational cohort. In 2014, 156 children diagnosed between 1981 and 2014 with ES, were analyzed. The median age at initial cytopenia was 5.4 (0.2-17.2 years old. For 85 sequential cases, the median delay between the episodes of AIHA and ITP was 2.4 years (0.1–16.3. The median follow-up since ES diagnosis was 6.5 years (0.1-28.8. ES revealed underlying diseases in 10% of children; in 60% of patients, various associated immune manifestations were observed, and ES remained primary in 30%. Five-year ITP and AIHA relapse-free survival were respectively 25% and 61%. In all, 69% of children required one or more than one second-line immune treatment and 15 patients (10% died at a median age of 14.3 years (1.7-28.1.This national work provides the first consistent clinical description for ES and underscores the high percentage of associated immune manifestations, the long-term complications, and treatment toxicities. Current challenges include the identification of underlying genetic immune dysregulations and better characterization of subgroups of patients and of second-line therapy strategies.

  14. Adolescent social isolation does not lead to persistent increases in anxiety- like behavior or ethanol intake in female long-evans rats.

    Science.gov (United States)

    Butler, Tracy R; Carter, Eugenia; Weiner, Jeffrey L

    2014-08-01

    Clinically, early life stress and anxiety disorders are associated with increased vulnerability for alcohol use disorders. In male rats, early life stress, imparted by adolescent social isolation, results in long-lasting increases in a number of behavioral risk factors for alcoholism, including greater anxiety-like behaviors and ethanol (EtOH) intake. Several recent studies have begun to use this model to gain insight into the relationships among anxiety measures, stress, EtOH intake, and neurobiological correlates driving these behaviors. As prior research has noted significant sex differences in the impact of adolescent stress on anxiety measures and EtOH drinking, the current study was conducted to determine if this same model produces an "addiction vulnerable" phenotype in female rodents. Female Long Evans rats were socially isolated (SI; 1/cage) or group housed (GH; 4/cage) for 6 weeks during adolescence. After this housing manipulation, behavioral assessment was conducted using the elevated plus maze, response to novelty in an open field environment, and the light/dark box. After behavioral testing, home cage EtOH drinking was assessed across an 8-week period. No group differences were detected in any of the behavioral measures of unconditioned anxiety-like behavior. Greater EtOH intake and preference were observed in SI females but these differences did not persist. The SI/GH model, which results in robust and enduring increases in anxiety measures and EtOH self-administration in male Long Evans rats, did not result in similar behavioral changes in female rats. These data, and that of others, suggest that adolescent social isolation is not a useful model with which to study neurobiological substrates linking antecedent anxiety and addiction vulnerability in female rats. Given the compelling epidemiological evidence that the relationship between chronic adolescent stress and alcohol addiction is particularly strong in women, there is clearly an urgent need

  15. Rare sugar D-psicose prevents progression and development of diabetes in T2DM model Otsuka Long-Evans Tokushima Fatty rats.

    Science.gov (United States)

    Hossain, Akram; Yamaguchi, Fuminori; Hirose, Kayoko; Matsunaga, Toru; Sui, Li; Hirata, Yuko; Noguchi, Chisato; Katagi, Ayako; Kamitori, Kazuyo; Dong, Youyi; Tsukamoto, Ikuko; Tokuda, Masaaki

    2015-01-01

    The fundamental cause of overweight and obesity is consumption of calorie-dense foods. We have introduced a zero-calorie sweet sugar, d-psicose (d-allulose), a rare sugar that has been proven to have strong antihyperglycemic and antihyperlipidemic effects, and could be used as a replacement of natural sugar for the obese and diabetic subjects. Above mentioned efficacy of d-psicose (d-allulose) has been confirmed in our previous studies on type 2 diabetes mellitus (T2DM) model Otsuka Long-Evans Tokushima Fatty (OLETF) rats with short-term treatment. In this study we investigated the long-term effect of d-psicose in preventing the commencement and progression of T2DM with the mechanism of preservation of pancreatic β-cells in OLETF rats. Treated OLETF rats were fed 5% d-psicose dissolved in water and control rats only water. Nondiabetic control rats, Long-Evans Tokushima Otsuka (LETO), were taken as healthy control and fed water. To follow the progression of diabetes, periodic measurements of blood glucose, plasma insulin, and body weight changes were continued till sacrifice at 60 weeks. Periodic in vivo body fat mass was measured. On sacrifice, pancreas, liver, and abdominal adipose tissues were collected for various staining tests. d-Psicose prevented the commencement and progression of T2DM till 60 weeks through the maintenance of blood glucose levels, decrease in body weight gain, and the control of postprandial hyperglycemia, with decreased levels of HbA1c in comparison to nontreated control rats. This improvement in glycemic control was accompanied by the maintenance of plasma insulin levels and the preservation of pancreatic β-cells with the significant reduction in inflammatory markers. Body fat accumulation was significantly lower in the treatment group, with decreased infiltration of macrophages in the abdominal adipose tissue. Our findings suggest that the rare sugar d-psicose could be beneficial for the prevention and control of obesity and

  16. The Junkyard in the Jungle: Transnational, Transnatural Nature in Karen Tei Yamashita’s Through the Arc of the Rain Forest

    Directory of Open Access Journals (Sweden)

    Begoña Simal

    2010-03-01

    Full Text Available In this new millennium the relatively young field of ecocriticism has had to face important transdisciplinary, transnational, and transnatural challenges. This article attempts to demonstrate how two of the major changes that environmental criticism is currently undergoing, the transnational turn and the transnatural challenge, have both been encoded in Through the Arc of the Rain Forest (1990, the first novel published by Karen Tei Yamashita. I particularly focus on a significant episode in Through the Arc of the Rain Forest, when a peculiar anthropogenic ecosystem is discovered, and interpret it according to Leo Marx’s classic paradigm of “the machine in the garden.” I intend to prove that Yamashita’s novel not only revisits the old master theory but also revamps it by destabilizing the classic human-nature divide inherent in first-wave ecocriticism and by adding the transnational ingredient. Thus, the machine-in-the-garden paradigm is updated in order to incorporate the broadening of current environmental criticism, both literally (globalization and conceptually (transnatural nature. While at times Marx’s paradigm may metamorphose in intriguing ways, the old trope also corroborates its continuing validity. Though filtered by the sieve of globalization and shaken by the emergence of cyborg ecosystems, “the machine in the garden” has survived as a compelling ecocritical framework, even if it occasionally mutates into a junkyard in the jungle.

  17. Four weeks' inhalation exposure of Long Evans rats to 4-tert-butyltoluene: Effect on evoked potentials, behaviour and brain neurochemistry

    DEFF Research Database (Denmark)

    Lam, Henrik Rye; Ladefoged, Ole; Østergaard, Grete

    2000-01-01

    Long-lasting central nervous system (CNS) neurotoxicity of 4-tert-butyltoluene (TBT) has been investigated using electrophysiology, behaviour, and neurochemistry in Long Evans rats exposed by inhalation to 0, 20, or 40 p.p.m. TBT 6 hr/day, 7 days/week for 4 weeks. Flash evoked potentials...... and somatosensory evoked potentials were not affected by TBT In Auditory Brain Stem Response there was no shift in hearing threshold, but the amplitude of the first wave was increased in both exposed groups at high stimulus levels. Three to four months after the end of exposure, behavioural studies in Morris water...... maze and eight-arm maze failed to demonstrate any TBT induced effects. Exposure was followed by a 5 months exposure-free period prior to gross regional and subcellular (synaptosomal) neurochemical investigations of the brain. TBT reduced the NA concentration in whole brain minus cerebellum...

  18. Metallothionein and antioxidant enzymes in Long-Evans Cinnamon rats treated with zinc

    Energy Technology Data Exchange (ETDEWEB)

    Medici, Valentina; Sturniolo, Giacomo Carlo; D' Inca, Renata [Department of Surgical and Gastroenterological Sciences, University of Padua, Padua (Italy); Santon, Alessandro; Giannetto, Sabrina; Albergoni, Vincenzo; Irato, Paola [Department of Biology, University of Padua, via U. Bassi 58/B, 35131 Padua (Italy)

    2002-09-01

    The Long-Evans Cinnamon (LEC) rat is a mutant animal model for Wilson's disease. It is known that an abnormal accumulation of Cu and Fe in the liver and low concentrations of both ceruloplasmin and Cu in the serum occur in these rats. The accumulation of Cu is explained by the defective expression of the Cu-transporting P-type ATPase gene, homologous to the gene for Wilson's disease (ATP7B). The aim of this work was to clarify the action mechanism of Zn, and to verify the role that this metal plays in LEC rats in short-term treatment experiments (1 and 2 weeks) on concentrations of Cu, Zn, Fe, metallothionein (MT), 8-hydroxy-2'-deoxyguanosine (oh{sup 8}dG) and on the activity of antioxidant enzymes. It is well known that Zn induces MT and has the ability to prevent redox-active metals, Cu and Fe, binding to and causing oxidative damage at active sites of Zn metalloenzymes and nonspecific binding sites on proteins. Zn administration reduces Cu and Fe transport from mucosal to serosal intestinal sides through competitive mechanisms. Our findings show that treatment with zinc acetate increases tissue Zn and MT contents and decreases Cu and Fe concentrations in the liver and kidneys, even if hepatic Zn and MT concentrations decrease with treatment period. Induction of MT synthesis by Zn contributes to the reduction in free radicals produced by Cu and Fe. We also observed that the superoxide dismutase (SOD)activity in liver decreases with treatment duration in association with the Cu and Fe liver decrease. However, the SOD activity in kidney increases in untreated rats at 2 weeks relative to those untreated for 1 week. (orig.)

  19. On Field Size and Success Probability in Network Coding

    DEFF Research Database (Denmark)

    Geil, Hans Olav; Matsumoto, Ryutaroh; Thomsen, Casper

    2008-01-01

    Using tools from algebraic geometry and Gröbner basis theory we solve two problems in network coding. First we present a method to determine the smallest field size for which linear network coding is feasible. Second we derive improved estimates on the success probability of random linear network...... coding. These estimates take into account which monomials occur in the support of the determinant of the product of Edmonds matrices. Therefore we finally investigate which monomials can occur in the determinant of the Edmonds matrix....

  20. Evans hole and non linear optical activity in Bis(melaminium) sulphate dihydrate: A vibrational spectral study.

    Science.gov (United States)

    Suresh Kumar, V R; Binoy, J; Dawn Dharma Roy, S; Marchewka, M K; Jayakumar, V S

    2015-01-01

    Bis(melaminium) sulphate dihydrate (BMSD), an interesting melaminium derivative for nonlinear optical activity, has been subjected to vibrational spectral analysis using FT IR and FT Raman spectra. The analysis has been aided by the Potential Energy Distribution (PED) of vibrational spectral bands, derived using density functional theory (DFT) at B3LYP/6-31G(d) level. The geometry is found to correlate well with the XRD structure and the band profiles for certain vibrations in the finger print region have been theoretically explained using Evans hole. The detailed Natural Bond Orbital (NBO) analysis of the hydrogen bonding in BMSD has also been carried out to understand the correlation between the stabilization energy of hyperconjugation of the lone pair of donor with the σ(∗) orbital of hydrogen-acceptor bond and the strength of hydrogen bond. The theoretical calculation shows that BMSD has NLO efficiency, 2.66 times that of urea. The frontier molecular orbital analysis points to a charge transfer, which contributes to NLO activity, through N-H…O intermolecular hydrogen bonding between the melaminium ring and the sulphate. The molecular electrostatic potential (MEP) mapping has also been performed for the detailed analysis of the mutual interactions between melaminium ring and sulphate ion. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. University of Geneva honours LHC project leader Lyn Evans at 450th anniversary ceremony. The honorary degrees, which recognize endeavours in human rights and in fostering dialogue between nations, were also awarded to Mary Robinson, Desmond Tutu, as well as Pascal Lamy .

    CERN Multimedia

    Maximilien Brice

    2009-01-01

    University of Geneva honours LHC project leader Lyn Evans at 450th anniversary ceremony. The honorary degrees, which recognize endeavours in human rights and in fostering dialogue between nations, were also awarded to Mary Robinson, Desmond Tutu, as well as Pascal Lamy .

  2. Perturbations to the lower ionosphere by tropical cyclone Evan in the South Pacific Region

    Science.gov (United States)

    Kumar, Sushil; NaitAmor, Samir; Chanrion, Olivier; Neubert, Torsten

    2017-08-01

    Very low frequency (VLF) electromagnetic signals from navigational transmitters propagate worldwide in the Earth-ionosphere waveguide formed by the Earth and the electrically conducting lower ionosphere. Changes in the signal properties are signatures of variations in the conductivity of the reflecting boundary of the lower ionosphere which is located in the mesosphere and lower thermosphere, and their analysis is, therefore, a way to study processes in these remote regions. Here we present a study on amplitude perturbations of local origin on the VLF transmitter signals (NPM, NLK, NAA, and JJI) observed during tropical cyclone (TC) Evan, 9-16 December 2012 when TC was in the proximity of the transmitter-receiver links. We observed a maximum amplitude perturbation of 5.7 dB on JJI transmitter during 16 December event. From Long Wave Propagation Capability model applied to three selected events we estimate a maximum decrease in the nighttime D region reference height (H') by 5.2 km (13 December, NPM) and maximum increase in the daytime D region H' by 6.1 km and 7.5 km (14 and 16 December, JJI). The results suggest that the TC caused the neutral densities of the mesosphere and lower thermosphere to lift and sink (bringing the lower ionosphere with it), an effect that may be mediated by gravity waves generated by the TC. The perturbations were observed before the storm was classified as a TC, at a time when it was a tropical depression, suggesting the broader conclusion that severe convective storms, in general, perturb the mesosphere and the stratosphere through which the perturbations propagate.

  3. Contemporary perspectives on psychosomatics in Germany: A commentary on Karen Gubb's paper, "Psychosomatics today: a review of contemporary theory and practice".

    Science.gov (United States)

    Frommer, Jörg

    2013-02-01

    Karen Gubb's (2013) review focuses on contemporary developments in psychoanalytic theory and practice in relation to psychosomatics, starting with some historical remarks, and Paris School with the Attachment approach. This paper examines the question of how the German scene fits into the issues raised in Gubb's discussion. From a historical point of view, psychosomatic thinking had already come into existence at the beginning of the twentieth century in internal medicine, influenced not only by Freud's ideas, but also by holistic philosophical approaches, anthropology, and semiotic systems theory as well. Psychosomatics is still under the influence of psychodynamic thinking, but as a required subject for all medical students, it is currently more involved in inpatient treatment settings than in psychoanalyses in the classical couch setting. Research projects using standardized questionnaires, neuroimaging, and other empirical methods have also proved that these treatments are as effective as therapy based on psychoanalytic concepts like alexithymia or the Attachment approach. In addition, qualitative methods have been implemented to grasp the fine-grained conscious and unconscious processes in the inner life of patients and in the verbal and nonverbal interaction phenomena of therapies. To sum up: Recent developments in psychoanalytic theory, which begin to overcome the differences among psychoanalytic schools in favor of re-erecting a common psychoanalytic understanding like that demonstrated in Gubb's article, fit together in bridging the gap between insights from classical psychoanalyses and results from empirical research.

  4. Opioidergic and dopaminergic modulation of cost/benefit decision-making in Long Evans Rats.

    Science.gov (United States)

    Morales, Ileana; Currie, Paul J; Hackenberg, Timothy D; Pastor, Raúl

    2017-10-01

    Eating disorders are associated with impaired decision-making and dysfunctional reward-related neurochemistry. The present study examined the potential contributions of dopamine and opioid signaling to these processes using two different decision-making tasks. In one task, Long Evans Rats chose between working for a preferred food (high-carbohydrate banana-flavored sucrose pellets) by lever pressing on a progressive-ratio schedule of reinforcement vs. obtaining less preferred laboratory chow that was concurrently available. In a second (effort-free) task, rats chose between the same two reinforcers when they were both available freely. Rats were trained in these tasks before receiving haloperidol (0.00, 0.05, 0.10mg/kg, intraperitoneally (i.p.)) or naloxone (0.0, 1.5, 3.0mg/kg, i.p.). In the first task, haloperidol decreased breakpoint, lever presses, number of reinforcers earned, and increased chow intake, whereas naloxone decreased breakpoint and number of reinforcers earned but had no effect on chow consumption. In the effort-free task, haloperidol reduced intakes of both foods without affecting preference, whereas naloxone selectively reduced the consumption of banana-pellets. The present findings support converging evidence suggesting that DA signaling affects processes more closely related to appetitive motivation, leaving other components of motivation unchanged. By contrast, opioid signaling appears to mediate aspects of hedonic feeding by selectively altering intakes of highly palatable foods. For preferred foods, both appetitive and consummatory aspects of food intake were altered by opioid receptor antagonism. Our findings argue against a general suppression of appetite by either compound, as appetite manipulations have been shown to unselectively alter intakes of both types of food regardless of the task employed. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Community engagement and the social context of targeted malaria treatment: a qualitative study in Kayin (Karen) State, Myanmar.

    Science.gov (United States)

    Sahan, Kate; Pell, Christopher; Smithuis, Frank; Phyo, Aung Kyaw; Maung, Sai Maung; Indrasuta, Chanida; Dondorp, Arjen M; White, Nicholas J; Day, Nicholas P J; von Seidlein, Lorenz; Cheah, Phaik Yeong

    2017-02-14

    The spread of artemisinin-resistance in Plasmodium falciparum is a threat to current global malaria control initiatives. Targeted malaria treatment (TMT), which combines mass anti-malarial administration with conventional malaria prevention and control measures, has been proposed as a strategy to tackle this problem. The effectiveness of TMT depends on high levels of population coverage and is influenced by accompanying community engagement activities and the local social context. The article explores how these factors influenced attitudes and behaviours towards TMT in Kayin (Karen) State, Myanmar. Semi-structured interviews were conducted with villagers from study villages (N = 31) and TMT project staff (N = 14) between March and July 2015. Community engagement consisted of a range of activities to communicate the local malaria situation (including anti-malarial drug resistance and asymptomatic malaria), the aims of the TMT project, and its potential benefits. Community engagement was seen by staff as integral to the TMT project as a whole and not a sub-set of activities. Attitudes towards TMT (including towards community engagement) showed that developing trusting relationships helped foster participation. After initial wariness, staff received hospitality and acceptance among villagers. Offering healthcare alongside TMT proved mutually beneficial for the study and villagers. A handful of more socially-mobile and wealthy community members were reluctant to participate. The challenges of community engagement included time constraints and the isolation of the community with its limited infrastructure and a history of conflict. Community engagement had to be responsive to the local community even though staff faced time constraints. Understanding the social context of engagement helped TMT to foster respectful and trusting relationships. The complex relationship between the local context and community engagement complicated evaluation of the community strategy

  6. Capire la realtà macroeconomica: una sfida* ( The challenge of macroeconomic understanding

    Directory of Open Access Journals (Sweden)

    E. MALINVAUD

    2013-12-01

    Full Text Available Il documento è un contributo ad una serie di ricordi e riflessioni sulle esperienze professionali di illustri economisti con Banca Nazionale del Lavoro Quarterly Review iniziati nel 1979. In esso Edmond Malinvaud descrive le varie sfide che percepito nel cercare di capire macroeconomiaThe paper is a contribution to a series of recollections and reflections on the professional experiences of distinguished economists which the Banca Nazionale del Lavoro Quarterly Review started in 1979. In it Edmond Malinvaud describes the various challenges he perceived in trying to understand macroeconomics.JEL: B31, E00

  7. Progressive ratio (PR) schedules and the sipometer: Do they measure wanting, liking, and/or reward? A tribute to Anthony Sclafani and Karen Ackroff.

    Science.gov (United States)

    Kissileff, H R; Herzog, M

    2018-03-01

    This paper honors the contributions made by Anthony (Tony) Sclafani and Karen Ackroff to both the Columbia University Seminar on Appetitive Behavior and to the field of ingestive behavior in general. We review their use of the progressive ratio (PR) licking paradigm, to determine whether the taste of sucrose, independent of its post-ingestive effects, is always positively reinforcing in animals. They demonstrated a monotonic increase in licking as concentration increased, and obtained results identical to those obtained with a lever-pressing paradigm, but licking was easier and more natural than lever pressing. The PR paradigm was translated to evaluate liquid food reward value in humans. An instrument (the sipometer) was devised that initially permitted a few seconds access to small amounts of a sweet beverage as the participants increased the time to obtain it in 3-5-sec increments. The device went through two refinements and currently delivers the reinforcer and measures the pressure exerted to obtain it. The sipometer is compared with other techniques for measuring motivation and reward. The use of the sipometer and the PR method are discussed in relation to the theoretical challenges inherent in measuring motivation and pleasure, from both psychological and behavioral economics perspectives, and why it is or is not important to separate these processes for both theoretical and practical applications. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Analysis of sensitivity to MK-801 treatment in a novel active allothetic place avoidance task and in the working memory version of the Morris water maze reveals differences between Long-Evans and Wistar rats

    Czech Academy of Sciences Publication Activity Database

    Valeš, Karel; Bubeníková-Valešová, V.; Klement, Daniel; Stuchlík, Aleš

    2006-01-01

    Roč. 55, č. 4 (2006), s. 383-388 ISSN 0168-0102 R&D Projects: GA MZd(CZ) NL7684; GA MŠk(CZ) 1M0517; GA MŠk(CZ) LC554; GA ČR(CZ) GP309/03/P126; GA ČR(CZ) GA309/06/1231 Institutional research plan: CEZ:AV0Z50110509 Keywords : Wistar/Long-Evans rats * MK-801 * cognition Subject RIV: FH - Neurology Impact factor: 1.953, year: 2006

  9. Effects of prenatal exposure to a low dose atrazine metabolite mixture on pubertal timing and prostate development of male Long-Evans rats

    Energy Technology Data Exchange (ETDEWEB)

    Stanko, Jason [National Institute of Environmental Health Sciences (NIEHS); Enoch, Rolondo [North Carolina Central University, Durham; Rayner, Jennifer L [ORNL; Davis, Christine [U.S. Environmental Protection Agency; Wolf, Douglas [U.S. Environmental Protection Agency; Malarkey, David [University of North Carolina, Chapel Hill; Fenton, Suzanne [National Institute of Environmental Health Sciences (NIEHS)

    2010-12-01

    The present study examines the postnatal reproductive development of male rats following prenatal exposure to an atrazine metabolite mixture (AMM) consisting of the herbicide atrazine and its environmental metabolites diaminochlorotriazine, hydroxyatrazine, deethylatrazine, and deisopropylatrazine. Pregnant Long-Evans rats were treated by gavage with 0.09, 0.87, or 8.73 mg AMM/kg body weight (BW), vehicle, or 100 mg ATR/kg BW positive control, on gestation days 15 19. Preputial separation was significantly delayed in 0.87 mg and 8.73 mg AMM-exposed males. AMM-exposed males demonstrated a significant treatment-related increase in incidence and severity of inflammation in the prostate on postnatal day (PND) 120. A dose-dependent increase in epididymal fat masses and prostate foci were grossly visible in AMM-exposed offspring. These results indicate that a short, late prenatal exposure to mixture of chlorotriazine metabolites can cause chronic prostatitis in male LE rats. The mode of action for these effects is presently unclear.

  10. Ethanol seeking by Long Evans rats is not always a goal-directed behavior.

    Directory of Open Access Journals (Sweden)

    Regina A Mangieri

    Full Text Available Two parallel and interacting processes are said to underlie animal behavior, whereby learning and performance of a behavior is at first via conscious and deliberate (goal-directed processes, but after initial acquisition, the behavior can become automatic and stimulus-elicited (habitual. With respect to instrumental behaviors, animal learning studies suggest that the duration of training and the action-outcome contingency are two factors involved in the emergence of habitual seeking of "natural" reinforcers (e.g., sweet solutions, food or sucrose pellets. To rigorously test whether behaviors reinforced by abused substances such as ethanol, in particular, similarly become habitual was the primary aim of this study.Male Long Evans rats underwent extended or limited operant lever press training with 10% sucrose/10% ethanol (10S10E reinforcement (variable interval (VI or (VR ratio schedule of reinforcement, or with 10% sucrose (10S reinforcement (VI schedule only. Once training and pretesting were complete, the impact of outcome devaluation on operant behavior was evaluated after lithium chloride injections were paired with the reinforcer, or unpaired 24 hours later. After limited, but not extended instrumental training, lever pressing by groups trained under VR with 10S10E and under VI with 10S was sensitive to outcome devaluation. In contrast, responding by both the extended and limited training 10S10E VI groups was not sensitive to ethanol devaluation during the test for habitual behavior.Operant behavior by rats trained to self-administer an ethanol-sucrose solution showed variable sensitivity to a change in the value of ethanol, with relative insensitivity developing sooner in animals that received time-variable ethanol reinforcement during training sessions. One important implication, with respect to substance abuse in humans, is that initial learning about the relationship between instrumental actions and the opportunity to consume ethanol

  11. Value of exercise echocardiography in heart failure with preserved ejection fraction: a substudy from the KaRen study.

    Science.gov (United States)

    Donal, Erwan; Lund, Lars H; Oger, Emmanuel; Reynaud, Amélie; Schnell, Frédéric; Persson, Hans; Drouet, Elodie; Linde, Cecilia; Daubert, Claude

    2016-01-01

    KaRen is a multicentre study designed to characterize and follow patients with heart failure and preserved ejection fraction (HFpEF). In a subgroup of patients with clinical signs of congestion but left ventricular ejection fraction (LVEF) >45%, we sought to describe and analyse the potential prognostic value of echocardiographic parameters recorded not only at rest but also during a submaximal exercise stress echocardiography. Exercise-induced changes in echo parameters might improve our ability to characterize HFpEF patients. Patients were prospectively recruited in a single tertiary centre following an acute HF episode with NT-pro-BNP >300 pg/mL (BNP > 100 pg/mL) and LVEF > 45% and reassessed by exercise echo-Doppler after 4-8 weeks of dedicated treatment. Image acquisitions were standardized, and analysis made at end of follow-up blinded to patients' clinical status and outcome. In total, 60 patients having standardized echocardiographic acquisitions were included in the analysis. Twenty-six patients (43%) died or were hospitalized for HF (primary outcome). The mean ± SD workload was 45 ± 14 watts (W). Mean ± SD resting LVEF and LV global longitudinal strain was 57.6 ± 9.5% and -14.5 ± 4.2%, respectively. Mean ± SD resting E/e' was 11.3 ± 4.7 and 13.1 ± 5.3 in those patients who did not and those who did experience the primary outcome, respectively (P = 0.03). Tricuspid regurgitation (TR) peak velocity during exercise were 3.3 ± 0.5 and 3.7 ± 0.5 m/s (P = 0.01). Exercise TR was independently associated with HF-hospitalization or death after adjustment on baseline clinical and biological characteristics. Exercise echocardiography may contribute to identify HFpEF patients and especially high-risk ones. Our study suggested a prognostic value of TR recorded during an exercise. That was demonstrated independently of the value of resting E/e'. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions

  12. The prognostic significance of atrial fibrillation in heart failure with preserved ejection function: insights from KaRen, a prospective and multicenter study.

    Science.gov (United States)

    Bosseau, Christian; Donal, Erwan; Lund, Lars H; Oger, Emmanuel; Hage, Camilla; Mulak, Geneviève; Daubert, Jean-Claude; Linde, Cecilia

    2017-06-01

    The prognostic value of atrial fibrillation (AF) in heart failure with preserved ejection fraction (HFPEF) remains controversial. We sought to study the prognostic value of AF in a prospective cohort and to characterize the HFPEF patients with AF. KaRen was a prospective, multicenter, international, observational study intended to characterize HFPEF; 538 patients presenting with an acute decompensated cardiac failure and a left ventricular EF > 45% were included. EKG and echocardiogram performed 4-8 week following the index hospitalization were analyzed in core centers. Clinical and echocardiographic characteristics of patients in sinus rhythm vs. with documented AF at enrolment (decompensated HF), upon their 4-8-week visit (in presumed stable clinical condition) and according to patients' cardiac history, were compared. The primary study endpoint was death from any cause or first hospitalization for decompensated heart failure (HF). A total of 413 patients (32% in AF) were analyzed, with a mean follow-up period of 28 months. The patients were primarily elderly individuals (mean age: 76.2 years), with a slight female predominance and a high prevalence of non-cardiovascular comorbidities. The baseline echocardiographic characteristics and the natriuretic peptide levels were indicative of a more severe heart condition among the patients with AF. However, the patients with AF exhibited a similar survival-free interval compared with the patients in sinus rhythm. In this elderly HFPEF population with a high prevalence of non-cardiovascular comorbidities, the presence of AF was not associated with a worse prognosis despite impaired clinical and echocardiographic features.ClinicalTrials.gov: NCT00774709.

  13. Improving urban visibility through fractal analysis of street edges: The case of John Evans Atta Mills High Street in Accra, Ghana

    Directory of Open Access Journals (Sweden)

    R.A. Oppong

    2017-06-01

    Full Text Available Streets are a representation of cities, and the image of a city is a reflection of its home country. Although attempts to ensure harmonious spatial and environmental development in Ghanaian settlements date back to the colonial era, these efforts have minimal physical manifestation in the urban fabric of the city of Accra. The Independence Arch of Ghana, an important landmark in the urban fabric and history of Accra, lacks the striking vista and approach it deserves. This paper introduces the use of fractal analysis of street edges to understand the characteristics of the John Evans Atta Mills (JEAM High Street for developing recommendations to improve visibility along its stretch and the overall image of the city. The box-counting method with visual survey was used in research. The pertinent questions this paper seeks to address are as follows: What factors affect the visibility and imageability of JEAM High Street? What design aspects should be considered to improve urban visibility along JEAM High Street? What is the link of fractals to urban design and architecture? The paper recommends various design considerations and qualities to improve the urban visibility and imageability of JEAM High Street.

  14. Atrazine-induced reproductive tract alterations after transplacental and/or lactational exposure in male Long-Evans rats

    International Nuclear Information System (INIS)

    Rayner, Jennifer L.; Enoch, Rolondo R.; Wolf, Douglas C.; Fenton, Suzanne E.

    2007-01-01

    Studies showed that early postnatal exposure to the herbicide atrazine (ATR) delayed preputial separation (PPS) and increased incidence of prostate inflammation in adult Wistar rats. A cross-fostering paradigm was used in this study to determine if gestational exposure to ATR would also result in altered puberty and reproductive tissue effects in the male rat. Timed-pregnant Long-Evans (LE) rats were dosed by gavage on gestational days (GD) 15-19 with 100 mg ATR/kg body weight (BW) or 1% methylcellulose (controls, C). On postnatal day (PND)1, half litters were cross-fostered, creating 4 treatment groups; C-C, ATR-C, C-ATR, and ATR-ATR (transplacental-milk as source, respectively). On PND4, male offspring in the ATR-ATR group weighed significantly less than the C-C males. ATR-ATR male pups had significantly delayed preputial separation (PPS). BWs at PPS for C-ATR and ATR-ATR males were reduced by 6% and 9%, respectively, from that of C-C. On PND120, lateral prostate weights of males in the ATR-ATR group were significantly increased over C-C. Histological examination of lateral and ventral prostates identified an increased distribution of inflammation in the lateral prostates of C-ATR males. By PND220, lateral prostate weights were significantly increased for ATR-C and ATR-ATR, but there were no significant changes in inflammation in either the lateral or ventral prostate. These results suggest that in LE rats, gestational ATR exposure delays PPS when male offspring suckle an ATR dam, but leads to increased lateral prostate weight via transplacental exposure alone. Inflammation present at PND120 does not increase in severity with time

  15. Attenuation of Diabetic Nephropathy in Otsuka Long-Evans Tokushima Fatty (OLETF Rats with a Combination of Chinese Herbs (Tangshen Formula

    Directory of Open Access Journals (Sweden)

    Haojun Zhang

    2011-01-01

    Full Text Available Diabetic nephropathy is one of the most significant microvascular complications in patients with type 2 diabetics. The concise mechanism of diabetic nephropathy is unknown and there is no successful treatment. The objective of study was to investigate effects of Chinese herbs (Tangshen Formula on diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty (OLETF rats. OLETF rats and LETO rats were divided into four groups: LETO control, OLETF diabetics, OLETF diabetics treated with Tangshen Formula, and OLETF diabetics treated with Monopril. Body weight, blood glucose, and 24 h urinary proteins were measured once every four weeks. Blood samples and kidney tissues were obtained for analyses of total cholesterol, triglyceride, whole blood viscosity, plasma viscosity, and pathohistological examination at 36 and 56 weeksrespectively. Untreated OLETF rats displayed diabetic nephropathy over the study period. Treatment of OLETF rats with Tangshen Formula attenuated the increases in blood glucose, body weight, 24 h urinary protein content, serum total cholesterol, whole blood viscosity and plasma viscosity at certain time. Treatment with Tangshen Formula also reduced glomerulosclerotic index and interstitial fibrotic index seen in OLETF rats. In conclusion, Tangshen Formula could attenuate the development of diabetic nephropathy in OLETF rat diabetic model.

  16. Vähetuntud E. A. Blumenfeldt / Jüri Hain

    Index Scriptorium Estoniae

    Hain, Jüri, 1941-

    2005-01-01

    Edmond Arnold Blumenfeldti õpingutest, loomingutee algusest, edukatest esinemisest Pariisi Sõltumatute Salongis, Eesti Kunstnikkude Ryhma arvukatel näitustel, ka tegevusest raamatukujunduse, tarbegraafika ja teatridekoratsiooni vallas Eestis ja Lätis

  17. Fatal pulmonary embolism following splenectomy in a patient with Evan's syndrome: case report and review of the literature.

    Science.gov (United States)

    Monga, Varun; Maliske, Seth M; Perepu, Usha

    2017-01-01

    Evans syndrome (ES) is a rare disease characterized by simultaneous or sequential development of autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP) with or without immune neutropenia. Splenectomy is one of the treatment options for disease refractory to medical therapy. Venous thromboembolism (VTE) following splenectomy for hematological diseases has an incidence of 10%. Here we describe a case report of a young patient hospitalized with severe hemolytic anemia with Hgb 4.8 g/dl. He developed thrombocytopenia with platelet nadir of 52,000/mm 3 , thus formally diagnosed with ES. He failed standard medical therapy. He underwent splenectomy and had a fatal outcome. Autopsy confirmed the cause of death as pulmonary embolism (PE). This case report and review of the literature highlight important aspects of the association between VTE, splenectomy, and hemolytic syndromes including the presence of thrombocytopenia. The burden of the disease is reviewed as well as various pathophysiologic mechanisms contributing to thromboembolic events in these patients and current perioperative prophylactic anticoagulation strategies. Despite an advancing body of literature increasing awareness of VTE following splenectomy, morbidity and mortality remains high. Identifying high risk individuals for thromboembolic complications from splenectomy remains a challenge. There are no consensus guidelines for proper perioperative and post-operative anti-coagulation. We encourage future research to determine which factors might be playing a role in increasing the risk for VTE in real time with hope of forming a consensus to guide management.

  18. EXISTENCE THEOREM FOR THE PRICES FIXED POINT PROBLEM OF THE OVERLAPPING GENERATIONS MODEL, VIA METRIC SPACES ENDOWED WITH A GRAPH

    Directory of Open Access Journals (Sweden)

    Magnolia Tilca

    2014-10-01

    Full Text Available The aim of this paper is to study the existence of the solution for the overlapping generations model, using fixed point theorems in metric spaces endowed with a graph. The overlapping generations model has been introduced and developed by Maurice Allais (1947, Paul Samuelson (1958, Peter Diamond (1965 and so on. The present paper treats the case presented by Edmond (2008 in (Edmond, 2008 for a continuous time. The theorem of existence of the solution for the prices fixed point problem derived from the overlapping generations model gives an approximation of the solution via the graph theory. The tools employed in this study are based on applications of the Jachymski fixed point theorem on metric spaces endowed with a graph (Jachymski, 2008

  19. Igale hingele jõululugemist

    Index Scriptorium Estoniae

    2006-01-01

    2006. a. Tallinnas kirjastuselt Ilo ilmunud Heiki Raudla raamatust eesti karikaturistist Edmond Valtmanist (1914-2005) "Edmund Valtman : eestlane, kes võitis Pulitzeri" ja kirjastuselt Sinisukk ilmunud raamatust" Täielik portreemaalimise kursus"

  20. Review of Financial Intelligence for Entrepreneurs: What You Really Need to Know about the Numbers by Karen Berman and Joe Knight, with John Case

    Directory of Open Access Journals (Sweden)

    H.L. Vacher

    2014-01-01

    Full Text Available Berman, Karen and Knight, Joe, with John Case. Financial Intelligence for Entrepreneurs: What You Really Need to Know about the Numbers, (Boston MA: Harvard Business Press, 2008. 285 pp. ISBN 978-1-4221-1915-0. From “The art of finance (and why it matters” (Part One through “Creating a financially intelligent company” (Part Eight, Financial Intelligence for Entrepreneurs is an engaging explanation and appreciation of financial statements and financial ratios. Short, easily digested chapters; just-in-time boxes to introduce terminology; easy, direct, in-text calculations from bare-bones, hypothetical financial statements to illustrate concepts; a 44-page appendix of crafted exercises on the income statement, balance sheet, cash-flow statement, and financial ratios from two public companies for deeper understanding; a detailed 19-page index for quick, after-you’ve-read-it navigation – all make for an efficient learning opportunity for readers who want a painless way to know about the numbers used in the world of business. Two quantitative literacy principles emerge as themes. The first is the “art of finance” (social construction: that is, the numbers are not totally objective; to varying extents, they reflect decisions, assumptions, and estimates in the accounting. The second is that ratios provide a window into the story that financial statements are able to tell. Written for entrepreneurs and company owners, the book ends with OBM (open-book management—a management philosophy based on financial literacy. The vision of this book is businesses in which all employees are financially literate and managers and owners are financially intelligent.

  1. Üllar Saaremäe - väge täis / Üllar Saaremäe ; interv. Veiko Märka

    Index Scriptorium Estoniae

    Saaremäe, Üllar, 1969-

    2007-01-01

    Näitleja, lavastaja ja teatrijuht on ka Eesti lava kuues Cyrano de Bergerac (Edmond Rostand'i "Cyrano de Bergerac" Rakvere Teatris, lavastaja Kalju Komissarov). Intervjuus oma lapsepõlvest, poliitikast, Cyranost ja muustki

  2. Freuds kvindelige bipersoner

    DEFF Research Database (Denmark)

    Lund, Jacob

    2014-01-01

    Anm. af Groce Smilevski: "Freuds søster" og Karen Mack og Jennifer Kaufman: "Freuds elskerinde"......Anm. af Groce Smilevski: "Freuds søster" og Karen Mack og Jennifer Kaufman: "Freuds elskerinde"...

  3. Obesity and type 2 diabetes, not a diet high in fat, sucrose, and cholesterol, negatively impacts bone outcomes in the hyperphagic Otsuka Long Evans Tokushima Fatty rat.

    Science.gov (United States)

    Ortinau, Laura C; Linden, Melissa A; Dirkes, Rebecca; Rector, R Scott; Hinton, Pamela S

    2017-12-01

    Obesity and type 2 diabetes (T2D) increase fracture risk; however, the association between obesity/T2D may be confounded by consumption of a diet high in fat, sucrose, and cholesterol (HFSC). The study objective was to determine the main and interactive effects of obesity/T2D and a HFSC diet on bone outcomes using hyperphagic Otuska Long Evans Tokushima Fatty (OLETF) rats and normophagic Long Evans Tokushima Otsuka (LETO) controls. At 8weeks of age, male OLETF and LETO rats were randomized to either a control (CON, 10 en% from fat as soybean oil) or HFSC (45 en% from fat as soybean oil/lard, 17 en% sucrose, and 1wt%) diet, resulting in four treatment groups. At 32weeks, total body bone mineral content (BMC) and density (BMD) and body composition were measured by dual-energy X-ray absorptiometry, followed by euthanasia and collection of blood and tibiae. Bone turnover markers and sclerostin were measured using ELISA. Trabecular microarchitecture of the proximal tibia and geometry of the tibia mid-diaphysis were measured using microcomputed tomography; whole-bone and tissue-level biomechanical properties were evaluated using torsional loading of the tibia. Two-factor ANOVA was used to determine main and interactive effects of diet (CON vs. HFSC) and obesity/T2D (OLETF vs. LETO) on bone outcomes. Hyperphagic OLEFT rats had greater final body mass, body fat, and fasting glucose than normophagic LETO, with no effect of diet. Total body BMC and serum markers of bone formation were decreased, and bone resorption and sclerostin were increased in obese/T2D OLETF rats. Trabecular bone volume and microarchitecture were adversely affected by obesity/T2D, but not diet. Whole-bone and tissue-level biomechanical properties of the tibia were not affected by obesity/T2D; the HFSC diet improved biomechanical properties only in LETO rats. Obesity/T2D, regardless of diet, negatively impacted the balance between bone formation and resorption and trabecular bone volume and

  4. Markers for blood-brain barrier integrity: how appropriate is Evans blue in the 21st century and what are the alternatives?

    Directory of Open Access Journals (Sweden)

    Norman Ruthven Saunders

    2015-10-01

    Full Text Available In recent years there has been a resurgence of interest in brain barriers and various roles their intrinsic mechanisms may play in neurological disorders. Such studies require suitable models and markers to demonstrate integrity and functional changes at the interfaces between blood, brain and cerebrospinal fluid. Studies of brain barrier mechanisms and measurements of plasma volume using dyes have a long-standing history, dating back to the late 19th-Century. Their use continues in spite of their known serious limitations in in vivo applications. These were well known when first introduced, but seem to have been forgotten since. Understanding these limitations is important because Evans blue is still the most commonly used marker of brain barrier integrity and those using it seem oblivious to problems arising from its in vivo application. The introduction of HRP in the mid 20th-Century was an important advance because its reaction product can be visualized at the electron microscopical level. Advantages and disadvantages these markers will be discussed together with a critical evaluation of alternative approaches. There is no single marker suitable for all purposes. A combination of different sized, visualisable dextrans and radiolabelled molecules currently seems to be the most appropriate approach for qualitative and quantitative assessment of barrier integrity.

  5. Viiralt vernulsja domoi

    Index Scriptorium Estoniae

    2005-01-01

    Eesti Kunstimuuseumi kogud täienesid Eduard Wiiralti kollektsiooniga, mille andis üle Stokholmi Eesti komitee, Herman Talviku töödega kunstniku perekonnalt ja Ameerikas surnud Edmond Valtmanni töödega

  6. "Le panache blanc" - bílý chochol na klobouku : gaskoňští kadeti a emblémy Cyrana z Bergeraku

    Czech Academy of Sciences Publication Activity Database

    Hrbata, Zdeněk

    2014-01-01

    Roč. 11, č. 21 (2014), s. 109-118 ISSN 1214-7915 Institutional support: RVO:68378068 Keywords : French literature * Dumas, Alexander * Cyrano from Bergerac * Rostand, Edmond Subject RIV: AJ - Letters, Mass-media, Audiovision

  7. "Nice guys finish last": influence of mate choice on reproductive success in Long-Evans rats.

    Science.gov (United States)

    Winland, C; Bolton, J L; Ford, B; Jampana, S; Tinker, J; Frohardt, R J; Guarraci, F A; Zewail-Foote, M

    2012-02-01

    The present study was designed to determine if male physiology and male reproductive behavior predict reproductive success in Long-Evans rats. Mating behavior was observed in sexually naïve, naturally cycling female rats during behavioral estrous that were given the opportunity to mate with two males simultaneously. DNA analysis of offspring born following these mating encounters was used to identify the paternity of each pup. In order to assess the effect of mate choice during these mating encounters on reproductive success, one male rat in each pair was categorized as the preferred mate if the female spent more time (>50%) with him during the mating test of the present study. Furthermore, each male in the pairs was categorized as "attractive" or "non-attractive" by computing the number of females that preferred each male across many mating tests. Similar to results reported in Lovell et al. (2007), during 76% of these mating tests the same male rat in each pair was preferred by different female rats. Overall attractiveness of individual male rats predicted reproductive success in the present study. Interestingly, "attractive" males sired significantly FEWER pups than "non-attractive" males. Neither behavioral (e.g., latency to first sexual stimulation, number of sexual stimulations) nor physiological measures (e.g., body weight, urinary testosterone levels) of male rats predicted their reproductive success. In conclusion, the present results indicate that certain features of some males are more attractive to females, but attractive males are at a reproductive disadvantage (as measured by the number of pups sired). Although basal urinary testosterone levels did not differ between males that sired the majority of pups in a litter and males that sired few or none of the pups in a litter, aggression and/or other physiological measures of fertility (e.g., penile reflexes) may differ between males that are attractive to females and those that have a reproductive

  8. The effects of cannabidiol (CBD) on Δ⁹-tetrahydrocannabinol (THC) self-administration in male and female Long-Evans rats.

    Science.gov (United States)

    Wakeford, Alison G P; Wetzell, Bradley B; Pomfrey, Rebecca L; Clasen, Matthew M; Taylor, William W; Hempel, Briana J; Riley, Anthony L

    2017-08-01

    Despite widespread cannabis use in humans, few rodent models exist demonstrating significant Δ⁹-tetrahydrocannabinol (THC) self-administration, possibly due to THC's co-occurring aversive effects, which impact drug reinforcement. Cannabis contains a number of phytocannabinoids in addition to THC, one of which, cannabidiol (CBD), has been reported to antagonize some of the aversive effects of THC. Given such effects of CBD, it is possible that it might influence THC intravenous self-administration in rodents. Accordingly, male and female Long-Evans rats were trained to self-administer THC over a 3-week period and then were assessed for the effects of CBD on responding for THC at 1:1 and 1:10 dose ratios or for the establishment of cocaine self-administration (as a positive control for drug self-administration). Consistent with previous research, THC self-administration was modest and only evident in a subset of animals (and unaffected by sex). Cocaine self-administration was high and evident in the majority of animals tested, indicating that the design was sensitive to drug reinforcement. There was no effect of CBD pretreatment on THC intravenous self-administration at any CBD:THC dose ratio. Future developments of animal models of THC self-administration and the examination of factors that affect its display remain important to establish procedures designed to assess the basis for and treatment of cannabis use and abuse. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  9. Drug Abuse - Multiple Languages

    Science.gov (United States)

    ... Burmese) PDF Facts about Marijuana - myanma bhasa (Burmese) MP3 Karen Chemical Dependency Taskforce of Minnesota Facts about ... Burmese) PDF Facts about Methamphetamine - myanma bhasa (Burmese) MP3 Karen Chemical Dependency Taskforce of Minnesota What Is ...

  10. 21. I avati Tartu Kunstimuuseumis Eesti Kunstnikkude Ryhma näitus

    Index Scriptorium Estoniae

    2005-01-01

    Väljas on Jaan Vahtra, Friedrich Histi, Eduard Ole, Felix Randeli, Henrik Olvi, Juhan Raudsepa, Märt Laarmani, Arnold Akbergi, Edmond Arnold Blumenfeldti ja Aleksander Krimsi looming. Kuraatorid Reet Mark ja Holger Rajavee. Ilmub artiklite kogumik

  11. 6 Common Cancers - Colorectal Cancer

    Science.gov (United States)

    ... Home Current Issue Past Issues 6 Common Cancers - Colorectal Cancer Past Issues / Spring 2007 Table of Contents For ... of colon cancer. Photo: AP Photo/Ron Edmonds Colorectal Cancer Cancer of the colon (large intestine) or rectum ( ...

  12. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Soome arhitekti Sami Rintala park Lõuna-Koreas Anyang'is ja hotell Põhja-Norras Kirkenes. Prantsuse arhitekti Edouard Francois' sotsiaalmaja Normandia väikelinnas Louviers'is. Kopenhaagenis ehitati silotornid ümber korterelamuteks (Hollandi arhitektuuribüroo MVRDV koos Taani büroo JJW Arkitekteriga). Energiasäästlik büroohoone Hollandis (büroo RAU). Johnston Marklee & Associatesi projekteeritud eramu Los Angelese lähedal

  13. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Stirlingi preemia Enric Mirallesele. Soome puitkirikutest. Sotsiaalmajad Sloveenias. Santa Caterina turuhoone Barcelonas. Ujuv maja Hollandis. Kalju küljes rippuv maja Jaapanis. Eesti arhitektuurist kataloogis "Emerging Identities - East" ja tšehhi ajakirjas "Stauba" 2005, nr. 6 Triin Ojari ajalooline ülevaade

  14. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Sardiinia Kunstimuuseum (Zaha Hadid), kortermaja Madridis (German de Sol), kunstimuuseum Riiga (Rem Koolhaas ja Reinier de Graaf), Tietgeni ühiselamu Kopenhaagenis (arhitektuuribüroo Lundgaard&Tranberg), büroohoone Baselis (Herzog&Meuron), eramu Washingtoni osariigis

  15. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Vaateplatvorm Grand Canyoni kohal. Francis Soleri ministeeriumihoone Pariisis. Eduardo Souto de Moura projekteeritud eramu basseiniga Portugalis. Jaapani arhitekti Shinichi Ogawa ühekorruseline betoonist eramu. Britta ja Francesco Buzzi villa Itaalias. Inglise REID Arhitektuuribüroos kavandatud büroode ja lukskorteritega maja Thamesi kaldal

  16. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Trossidega majale kinnitatud rippuv tuba (autor Stefan Eberstadt); disainikooli hoone Saksamaa tööstuspiirkonnas (arhitektid Kazuyo Sejima ja Ryue Nishizawa); hiidlille kujuline elamu Hollandis (arhitektid Ben Huygen ja Jasper Jägers); Fuji mäe kujuline eramu Jaapanis (arhitekt Yuko Nagayama); AR Arhitektuuriauhinnad noorele arhitektile; laeva ja püramiidi hübriidi vormiga elamu (arhitekt Katsuhiro Miyamoto)

  17. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Richard Rogersi Madridi lennujaam, prantsuse arhitektide odavad mudelmajad, jaapani arhitektide lükandseintega eramu nn. räästamaja, Saksamaal korraldatud multifunktsionaalsete ühiselamu/hostelitubade arhitektuurikonkursi tulemustest, arhitekt Carme Pinose kontorihoone Torre Cube Mehhikos, Sean Godselli projekteeritud eramu Austraalias, arhitektuuribüroo Alphaville projekteeritud eramu Jaapanis, Stefan Hauseri (kunstnikunimega Placed To Ride) projekteeritud Malmö rulapark

  18. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Eramu Jaapanis (arh. büroo TNA Arhitektid) ja Itaalias (arh. Massimo Curzi). Elektrijaama territooriumi ümberplaneerimine Soomes Hanasaaris. Berliini Spandau linnaossa rajatud lasteaed "Pipi paradiis" (arh. büroo Baupiloten). Restoran Inglismaal Littlehamptoni rannikul (arh. Thomas Heatherwick ja Jane Wood)

  19. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Radikaalne kortermaja Itaalias Bolzanos, kus terrassid ja korteri vahelduvad fassaadil ja lähevad sujuvalt üksteiseks üle. Pouya Khazaeli Parsa projekteeritud villa Teherani lähedal, mis valminud Le Corbusier' loomingu eeskujul. Bitumi ja Pekka Manneri ülimoodne avalik tualett Suomenlinnas. Wolfgang Feyferliki ja Susi Fritzeri projekteeritud eramu, mis sobitub edukalt tammede vahele. Mätaskatusega pargipaviljon Lääne-Holsteinis. Šveitsi Alpidesse projekteeritud elamiskompleks, kus leitud vanaeuroopalik tasakaal vana ja uue vahel

  20. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Austria büroo Coop Himmelb(l)au projekteeritud eramu, mis mõjub skulpturaalse vormina (sisekujundus Virginia Moedelt), uus raamatukoguhoone Prahas, mille projekteeris Jan Kaplicky, juurdeehitus vanale majale Šveitsi Alpides, Sebastian Irarrazavali metallist eramu, mägimaja Bosnias ja betoonist joogikiosk Austrias (projekt Wellmann Ladingerilt), mis pakub ka ööbimisvõimalust

  1. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Tate Moderni juurdeehitus Londonis, arhitektid Jacques Herzog ja Pierre de Meuron. Šveitsi arhitektuuribüroos Geninasca Delefortrie projekteeritud eramu. Konkursist Vockerode elektrijaama rekonstrueerimiseks Saksamaal. Portugali arhitekti Alvaro Leite Siza Viera projekteeritud eramu. VIP paviljon Valencias 2007. aasta purjeregatiks, arhitekt David Chipperfild. Berliini uus raudteejaama peahoone. Madridi lennujaama Barajas uus terminal, büroo Richard Rogers Partnership, võitis RIBA Stirling Prize'i

  2. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Jackson Clements Borrowsi projekteeritud eramu Melbourne'is. Dominic Stevensi eramu Iirimaal. Büroo Soeters Van Eldonki kortermajad Amsterdamis. Le Corbusier' visandatud kirik Prantsusmaal Firminy-Vert'is. Ameerika arhitektuuribüroo Morphosis projekteeritud Phare Tower Pariisis

  3. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Itaalia arhitekti Raimondo Guidacci kortermajad Orsara di Puglias. Paadikujuline eramu Jaapanis. Saksa arhitekti Titus Bernhardi projekteeritud eramu Augsburgis. Hamburgi Hafencity projektist. Suvepaviljon Londoni Hyde Park'is. Pilvelõhkujad Tiranas

  4. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Chiba Manabu surfajate rannamaja Tokyo lähedal, Fausto Forni ja Stefano Gueli eramu Šveitsi mägedes, Daniel Libeskindi Denveri muuseumi laiendus (arhitekt Gio Ponti), automuuseumitest, NU Arhitektuuriateljee kavandatud bürooga elamu Hollandis, Arhitektuuribüroo Cukrowicz Nachbaur Architekten projekteeritud kortermaja väljanägemisega kahepereelamu Saksamaal

  5. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Jun Aoki projekteeritud Vuittoni glamuuripesa ja pulmakabel Tokios, Toyo Ito kaubanduskeskus Singapuris, Lorcan O'Herlihy projekteeritud Mill Valley villa San Francisco lahe ääres, Zaha Hadidi projekteeritud vinoteek Barcelonas, mis on vanast paviljonist ümber ehitatud, Dietmar Fiechtingeri projekteeritav sild ühendamaks maismaad Mont-Saint-Micheli kloostri saarega ja Cino Zucchini projekteeritud kortermajad Milano tööstuspiirkonda

  6. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Mario Garzaniti korrusmaja Brüsselis, Ryue Nishizawa kortermaja Tokyos, Hamburgi arhitektuuribüroo Blauraum loomingust, Michael P. Johnsoni eramu Phoenixis, jaapani arhitekti Kei'ichi Irie ja Power Unit Studio loodud monoliitbetoonist eramu Chita linnas, hollandi arhitektuuribüroo OMA loomingust, inglise büroo Peter Barber Architects lahendus Londoni ühe eeslinna kvartalile

  7. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Elamurajoon Witbrant (Jacq de Brouwer, Erna van Sambeek) Tilburgis Lõuna-Hollandis. Kaubakonteineritest kokkuopandav reisimuuseum (Shigeru Ban). Säästlik, kerge, transporditav ja vähese materjalikuluga näidismaja (Richard Horden, saksa AB Haack + Höpfner). Ristikujuline maja (Bevk Perovic Arhitektid) Ljubljanas. Onnist inspireeritud pargikeskus (Chris Thurlbourne) Taani Rahvuspargis. Eestile ja muuseumidele pühendatud Soome arhitektuuriajakirja Arkkitehti 2006. a. 3. numbrist. Autoritest nimetatud Jorma Mukala, Pekka Vapaavuori, Leonhard Lapin, Triin Ojari, Tarja Nurmi (retsensioon Karin Hallas-Murula raamatule "Soome-Eesti : sajand arhitektuurisuhted)

  8. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Klaasist müramüür ja autosalong Hollandis (arhit. büroo ONL). Elamuarhitektuur Pariisi eeslinnades (arh. Marini ja Trottini). Kasutatud paneelidest ökoeramud Saksamaal (arh. Herve Biele ja insener Claus Asam). Eramud Austria ja Jaapanis. Automuuseum Stuttgardis (arh.Ben van Berkel ja Caroline Bos). USA arhitekti Lorcan O'Herlihy rannamaja. Plastfassaad Hamburgis

  9. Arhitektuuriuudised / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Mari Cucinella päikesepaneelidel töötav Pekingi uus ülikoolihoone. Arhitektuuristuudio Van der Merwe Miszewski projekteeritud eramu, mis koosneb kolmest, üksteisega risti asetsevast hooneosast, maastiku kujundaja Tarba Klitzner. Hiroaki Ohtani ribimaja 34 m2 suurusel krundil Kobes. AB Verstas Arkkitehdit Oy projekteeritud lahtise vahekäiguga saun. Gernot Hertli kuupjas eramaja romantilises Austria vanalinnas Waidhofen an der Ybbs. Pekka Mäki suvevilla Turu saarestiku kaljusel rannikul

  10. Viin! / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Näitused austria kaasaegsest arhitektuurist Eesti Arhitektuurimuuseumis kuni 21. V: "Viin: linnaehitus ja uusim arhitektuur" suures saalis (kuraator Leopold Dungl), kaasneb kataloog; "Elamuehitus Viinis: arhitektuur igaühele" galeriil (näituse idee: Wolfgang Förster, Dietmar Steiner, Alexandra Viehhauser, kuraator A. Viehhauser, kujundus - Span-Arhitektid: Matias del Campo, Sandra Manninger, Sebastian Michalski)

  11. Chronic ethanol exposure increases voluntary home cage intake in adult male, but not female, Long-Evans rats.

    Science.gov (United States)

    Morales, Melissa; McGinnis, Molly M; McCool, Brian A

    2015-12-01

    The current experiment examined the effects of 10 days of chronic intermittent ethanol (CIE) exposure on anxiety-like behavior and home cage ethanol intake using a 20% intermittent access (M, W, F) paradigm in male and female Long-Evans rats. Withdrawal from alcohol dependence contributes to relapse in humans and increases in anxiety-like behavior and voluntary ethanol consumption in preclinical models. Our laboratory has shown that 10 days of CIE exposure produces both behavioral and neurophysiological alterations associated with withdrawal in male rats; however, we have yet to examine the effects of this exposure regime on ethanol intake in females. During baseline, females consumed more ethanol than males but, unlike males, did not show escalations in intake. Rats were then exposed to CIE and were again given intermittent access to 20% ethanol. CIE males increased their intake compared to baseline, whereas air-exposed males did not. Ethanol intake in females was unaffected by CIE exposure. Notably, both sexes expressed significantly elevated withdrawal-associated anxiety-like behavior in the plus maze. Finally, rats were injected with the cannabinoid CB1 receptor antagonist, SR141716A (0, 1, 3, 10mg/kg, i.p.) which reduced ethanol intake in both sexes. However, females appear to be more sensitive to lower doses of this CB1 receptor antagonist. Our results show that females consume more ethanol than males; however, they did not escalate their intake using the intermittent access paradigm. Unlike males, CIE exposure had no effect on drinking in females. It is possible that females may be less sensitive than males to ethanol-induced increases in drinking after a short CIE exposure. Lastly, our results demonstrate that males and females may have different pharmacological sensitivities to CB1 receptor blockade on ethanol intake, at least under the current conditions. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Behavioral Phenotyping of Juvenile Long-Evans and Sprague-Dawley Rats: Implications for Preclinical Models of Autism Spectrum Disorders.

    Directory of Open Access Journals (Sweden)

    Katherine M Ku

    Full Text Available The laboratory rat is emerging as an attractive preclinical animal model of autism spectrum disorder (ASD, allowing investigators to explore genetic, environmental and pharmacological manipulations in a species exhibiting complex, reciprocal social behavior. The present study was carried out to compare two commonly used strains of laboratory rats, Sprague-Dawley (SD and Long-Evans (LE, between the ages of postnatal day (PND 26-56 using high-throughput behavioral phenotyping tools commonly used in mouse models of ASD that we have adapted for use in rats. We detected few differences between young SD and LE strains on standard assays of exploration, sensorimotor gating, anxiety, repetitive behaviors, and learning. Both SD and LE strains also demonstrated sociability in the 3-chamber social approach test as indexed by spending more time in the social chamber with a constrained age/strain/sex matched novel partner than in an identical chamber without a partner. Pronounced differences between the two strains were, however, detected when the rats were allowed to freely interact with a novel partner in the social dyad paradigm. The SD rats in this particular testing paradigm engaged in play more frequently and for longer durations than the LE rats at both juvenile and young adult developmental time points. Results from this study that are particularly relevant for developing preclinical ASD models in rats are threefold: (i commonly utilized strains exhibit unique patterns of social interactions, including strain-specific play behaviors, (ii the testing environment may profoundly influence the expression of strain-specific social behavior and (iii simple, automated measures of sociability may not capture the complexities of rat social interactions.

  13. DECEMBER JMBR 13 - 2 correction.cdr

    African Journals Online (AJOL)

    Fine Print

    community perceptions and factors affecting the utilization of health services in a rural community in Southern ... healthcare workers; poor quality of care; and proximity to the ..... K, Edmond K. Effect of geographical access to health facilities on ...

  14. MO Aziken, *OO Kalu *Department of Obstetrics and Gynaecolog

    African Journals Online (AJOL)

    drclement

    management of infertility.1,3,4,5 The IVF was performed ... success rate (human reproduction itself being a ... especially needed in a resource-limited setting. .... and Gynaecology 7th edition. Ed. Edmonds K. Blackwell Publishing. 461-478. 6.

  15. Taurine ameliorates hyperglycemia and dyslipidemia by reducing insulin resistance and leptin level in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term diabetes

    Science.gov (United States)

    Oh, Da Hee; Kim, Jung Yeon; Lee, Bong Gn; You, Jeong Soon; Chang, Kyung Ja; Chung, Hyunju; Yoo, Myung Chul; Yang, Hyung-In; Kang, Ja-Heon; Hwang, Yoo Chul; Ahn, Kue Jeong; Chung, Ho-Yeon

    2012-01-01

    This study aimed to determine whether taurine supplementation improves metabolic disturbances and diabetic complications in an animal model for type 2 diabetes. We investigated whether taurine has therapeutic effects on glucose metabolism, lipid metabolism, and diabetic complications in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term duration of diabetes. Fourteen 50-week-old OLETF rats with chronic diabetes were fed a diet supplemented with taurine (2%) or a non-supplemented control diet for 12 weeks. Taurine reduced blood glucose levels over 12 weeks, and improved OGTT outcomes at 6 weeks after taurine supplementation, in OLETF rats. Taurine significantly reduced insulin resistance but did not improve β-cell function or islet mass. After 12 weeks, taurine significantly decreased serum levels of lipids such as triglyceride, cholesterol, high density lipoprotein cholesterol, and low density lipoprotein cholesterol. Taurine significantly reduced serum leptin, but not adiponectin levels. However, taurine had no therapeutic effect on damaged tissues. Taurine ameliorated hyperglycemia and dyslipidemia, at least in part, by improving insulin sensitivity and leptin modulation in OLETF rats with long-term diabetes. Additional study is needed to investigate whether taurine has the same beneficial effects in human diabetic patients. PMID:23114424

  16. Indigenous systems of forest classification: understanding land use patterns and the role of NTFPs in shifting cultivators' subsistence economies.

    Science.gov (United States)

    Delang, Claudio O

    2006-04-01

    This article discusses the system of classification of forest types used by the Pwo Karen in Thung Yai Naresuan Wildlife Sanctuary in western Thailand and the role of nontimber forest products (NTFPs), focusing on wild food plants, in Karen livelihoods. The article argues that the Pwo Karen have two methods of forest classification, closely related to their swidden farming practices. The first is used for forest land that has been, or can be, swiddened, and classifies forest types according to growth conditions. The second system is used for land that is not suitable for cultivation and looks at soil properties and slope. The article estimates the relative importance of each forest type in what concerns the collection of wild food plants. A total of 134 wild food plant species were recorded in December 2004. They account for some 80-90% of the amount of edible plants consumed by the Pwo Karen, and have a base value of Baht 11,505 per year, comparable to the cash incomes of many households. The article argues that the Pwo Karen reliance on NTFPs has influenced their land-use and forest management practices. However, by restricting the length of the fallow period, the Thai government has caused ecological changes that are challenging the ability of the Karen to remain subsistence oriented. By ignoring shifting cultivators' dependence on such products, the involvement of governments in forest management, especially through restrictions imposed on swidden farming practices, is likely to have a considerable impact on the livelihood strategies of these communities.

  17. Selective leaching studies of sediments from a seamount flank in the Central Indian Basin: Resolving hydrothermal, volcanogenic and terrigenous sources using major, trace and rare-earth elements

    Digital Repository Service at National Institute of Oceanography (India)

    Mascarenhas-Pereira, M.B.L.; Nath, B.N.

    with increasing distance from the initial vent source (Mitra et al., 1994; German et al., 2002; Edmonds and German, 2004). Sherrell et al. 15 (1999) contend that in a time scale of plume advection, adsorption reflects near–instanteous equilibrium...

  18. Impacts of fiscal policies to improve nutrition in South Africa

    International Development Research Centre (IDRC) Digital Library (Canada)

    Lead Researcher: Karen Hofman. Karen.Hofman@wits.ac.za. Recipient institution: Wits Medical School, School of. Public Health, South Africa. For more information on this project, contact Wardie. Leppan, Senior Program Specialist, Ottawa, Canada. (wleppan@idrc.ca). The Non-Communicable Disease Prevention (NCDP) ...

  19. Hispaanias auhinnati Eesti jalatsikunstnikke / Tiiu Laks

    Index Scriptorium Estoniae

    Laks, Tiiu, 1984-

    2006-01-01

    Eesti Kunstiakadeemia nahakunsti magistrandid Maris Pill ja Karen Milistver esinesid edukalt võistlusel "Lapiz de Oro 2006". Maris Pill võitis jalatsiprototüüpide kategoorias tööga "Two Faces" Kuldpliiatsi ja Karen Milistver tööga "Showy shoes" teise auhinna

  20. Health Risks of an Inactive Lifestyle - Multiple Languages

    Science.gov (United States)

    ... Hour or More of Physical Activity - فارسی (Farsi) MP3 Minnesota Department of Health Healthy Numbers for Kids ... Time to Two Hours or Less - فارسی (Farsi) MP3 Minnesota Department of Health Karen (S’gaw Karen) Expand ...

  1. Exercise for Children - Multiple Languages

    Science.gov (United States)

    ... 0 (Eat Well, Sleep, Stay Active) - فارسی (Farsi) MP3 Minnesota Department of Health Healthy Numbers for Kids ... Hour or More of Physical Activity - فارسی (Farsi) MP3 Minnesota Department of Health Karen (S’gaw Karen) Expand ...

  2. Chronic social instability increases anxiety-like behavior and ethanol preference in male Long Evans rats.

    Science.gov (United States)

    Roeckner, Alyssa R; Bowling, Alexandra; Butler, Tracy R

    2017-05-01

    Chronic stress during adolescence is related to increased prevalence of anxiety disorders and alcohol use disorders in humans. This phenotype has been consistently recapitulated in animal models with male subjects, but models using female subjects are fewer. The aim of these studies was to test the hypothesis that chronic social instability (CSI) during adolescence engenders increased anxiety-like behavior, increased corticosterone, and greater ethanol intake and/or preference than control groups in male and female rats. A chronic social instability (CSI) procedure was conducted in separate cohorts of female and male adolescent Long Evans rats. CSI included daily social isolation for 1h, and then pair housing with a novel cage mate for 23h until the next 1h isolation period from PND 30-46. Control groups included social stability (SS), chronic isolation (ISO), and acute social instability (aSI). At PND 49-50, anxiety-like behavior was assessed on the elevated plus maze, and on PND 51 tails bloods were obtained for determination of corticosterone (CORT) levels. This was followed by 4weeks of ethanol drinking in a home cage intermittent access ethanol drinking paradigm (PND 55-81 for males, PND 57-83 for females). Planned contrast testing showed that the male CSI group had greater anxiety-like behavior compared controls, but group differences were not apparent for CORT. CSI males had significantly higher levels of ethanol preference during drinking weeks 2-3 compared to all other groups and compared to SS and ISO groups in week 4. For the female cohort, we did not observe consistent group differences in anxiety-like behavior, CORT levels were unexpectedly lower in the ISO group only compared to the other groups, and group differences were not apparent for ethanol intake/preference. In conclusion, chronic stress during adolescence in the form of social instability increases anxiety-like behavior and ethanol preference in male rats, consistent with other models of

  3. In vivo magnetic resonance imaging of atherosclerotic lesions with a newly developed Evans blue-DTPA-gadolinium contrast medium in apolipoprotein-E-deficient mice.

    Science.gov (United States)

    Yasuda, Satoshi; Ikuta, Kenjiro; Uwatoku, Toyokazu; Oi, Keiji; Abe, Kohtaro; Hyodo, Fuminori; Yoshimitsu, Kengo; Sugimura, Kohtaro; Utsumi, Hideo; Katayama, Yoshiki; Shimokawa, Hiroaki

    2008-01-01

    Magnetic resonance imaging (MRI) contrast agents that specifically detect atherosclerotic plaque may be useful for the noninvasive detection of the plaque. We have recently developed a new contrast agent, Evans blue-DTPA-gadolinium (EB-DTPA-Gd), which selectively accumulates vascular lesions with endothelial removal. In this study, we examined whether EB-DTPA-Gd is also useful for in vivo imaging of atherosclerotic plaques. We used male apolipoprotein-E-deficient (ApoE-/-) mice of different ages (3, 6 and 12 months old) and age-matched male wild-type mice. After a single intravenous administration of EB-DTPA-Gd (160 microM/kg body weight), MRI T(1) signal was obtained in vivo. Increased signal intensity in the aortic wall was noted within 10-20 min after intravenous injection of EB-DTPA-Gd and was maintained for 30 min. The MRI enhancement in the aorta of ApoE-/- mice was increased in accordance with age, whereas no such enhancement was noted in wild-type mice. Histological examination demonstrated that there was a topological correlation between the site of MRI enhancement and that of atherosclerotic plaque. These results indicate that EB-DTPA-Gd is a useful MRI contrast medium for the in vivo detection of atherosclerotic plaques. Copyright (c) 2007 S. Karger AG, Basel.

  4. Reduced hippocampal dendritic spine density and BDNF expression following acute postnatal exposure to di(2-ethylhexyl phthalate in male Long Evans rats.

    Directory of Open Access Journals (Sweden)

    Catherine A Smith

    Full Text Available Early developmental exposure to di(2-ethylhexyl phthalate (DEHP has been linked to a variety of neurodevelopmental changes, particularly in rodents. The primary goal of this work was to establish whether acute postnatal exposure to a low dose of DEHP would alter hippocampal dendritic morphology and BDNF and caspase-3 mRNA expression in male and female Long Evans rats. Treatment with DEHP in male rats led to a reduction in spine density on basal and apical dendrites of neurons in the CA3 dorsal hippocampal region compared to vehicle-treated male controls. Dorsal hippocampal BDNF mRNA expression was also down-regulated in male rats exposed to DEHP. No differences in hippocampal spine density or BDNF mRNA expression were observed in female rats treated with DEHP compared to controls. DEHP treatment did not affect hippocampal caspase-3 mRNA expression in male or female rats. These results suggest a gender-specific vulnerability to early developmental DEHP exposure in male rats whereby postnatal DEHP exposure may interfere with normal synaptogenesis and connectivity in the hippocampus. Decreased expression of BDNF mRNA may represent a molecular mechanism underlying the reduction in dendritic spine density observed in hippocampal CA3 neurons. These findings provide initial evidence for a link between developmental exposure to DEHP, reduced levels of BDNF and hippocampal atrophy in male rats.

  5. New Perspectives for Old Clusters: Anderson-Evans Anions as Building Blocks of Large Polyoxometalate Frameworks in a Series of Heterometallic 3 d-4 f Species.

    Science.gov (United States)

    Artetxe, Beñat; Reinoso, Santiago; San Felices, Leire; Lezama, Luis; Gutiérrez-Zorrilla, Juan M; Vicent, Cristian; Haso, Fadi; Liu, Tianbo

    2016-03-18

    A series of nine [Sb7W36O133Ln3M2(OAc)(H2O)8](17-) heterometallic anions (Ln3M2; Ln=La-Gd, M=Co; Ln=Ce, M=Ni and Zn) have been obtained by reacting 3 d metal disubstituted Krebs-type tungstoantimonates(III) with early lanthanides. Their unique tetrameric structure contains a novel {MW9O33} capping unit formed by a planar {MW6O24} fragment to which three {WO2} groups are condensed to form a tungstate skeleton identical to that of a hypothetical trilacunary derivative of the ɛ-Keggin cluster. It is shown, for the first time, that classical Anderson-Evans {MW6O24} anions can act as building blocks to construct purely inorganic large frameworks. Unprecedented reactivity in the outer ring of these disk-shaped species is also revealed. The Ln3M2 anions possess chirality owing to a {Sb4O4} cluster being encapsulated in left- or right-handed orientations. Their ability to self-associate in blackberry-type vesicles in solution has been assessed for the Ce3Co2 derivative. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Interview with a quality leader--Karen Davis, executive director of The Commonwealth Fund. Interview by Lecia A. Albright.

    Science.gov (United States)

    Davis, Karen

    2009-01-01

    Karen Davis is president of The Commonwealth Fund, a national philanthropy engaged in independent research on health and social policy issues. Dr. Davis is a nationally recognized economist, with a distinguished career in public policy and research. Before joining the Fund, she served as chairman of the Department of Health Policy and Management at The Johns Hopkins School of Public Health, where she also held an appointment as professor of economics. She served as deputy assistant secretary for health policy in the Department of Health and Human Services from 1977 to 1980, and was the first woman to head a U.S. Public Health Service agency. Before her government career, Ms. Davis was a senior fellow at the Brookings Institution in Washington, DC; a visiting lecturer at Harvard University; and an assistant professor of economics at Rice University. A native of Oklahoma, she received her PhD in economics from Rice University, which recognized her achievements with a Distinguished Alumna Award in 1991. Ms. Davis is the recipient of the 2000 Baxter-Allegiance Foundation Prize for Health Services Research. In the spring of 2001, Ms. Davis received an honorary doctorate in human letters from John Hopkins University. In 2006, she was selected for the Academy Health Distinguished Investigator Award for significant and lasting contributions to the field of health services research in addition to the Picker Award for Excellence in the Advancement of Patient Centered Care. Ms. Davis has published a number of significant books, monographs, and articles on health and social policy issues, including the landmark books HealthCare Cost Containment, Medicare Policy, National Health Insurance: Benefits, Costs, and Consequences, and Health and the War on Poverty. She serves on the Board of Visitors of Columbia University, School of Nursing, and is on the Board of Directors of the Geisinger Health System. She was elected to the Institute of Medicine (IOM) in 1975; has served two

  7. Decreased sexual motivation and heightened anxiety in male Long-Evans rats are correlated with the memory for a traumatic event.

    Science.gov (United States)

    Hawley, Wayne R; Grissom, Elin M; Belkin, Mark N; James, Thomas F; Dohanich, Gary P

    2013-05-01

    Individuals suffering from posttraumatic stress disorder (PTSD) frequently report disturbances in sexual functioning in addition to alterations in their affective behaviors. Notably, maladaptive cognitions and dysfunctional behaviors are perpetuated by the emergence of the intrusive thoughts that characterize the disorder. In rats, reminders of a traumatic event designed to simulate intrusive thoughts are associated with impairments in affective, social, and sexual behaviors. The current study examined the relationship between the memory for a traumatic event and changes in sexual and affective behaviors in male Long-Evans rats (N = 36). The trauma featured a combination stressor consisting of simultaneous exposure to a footshock and the odor of soiled cat litter. Memory for the trauma was reactivated by re-exposures to the context of the trauma in the absence of stressors and confirmed by assessing the percentage of time spent freezing. Following the second and final reminder, traumatized males exhibited reduced sexual motivation and increased anxiety, signified by longer latencies to achieve their first mount on a post-stress test of sexual behavior, and longer latencies to begin feeding in a novel environment, respectively. Correlational analyses revealed that decreased sexual motivation and heightened anxiety were predicted by the memory for the trauma as indicated by the time spent freezing during the re-exposures. The findings from the current study have implications for understanding the relationship between stress and sexual functioning and indicate that the impairments in sexual behavior that often occur in individuals with PTSD may be impacted by their memory for the trauma.

  8. Graphic Organizers for Secondary Students with Learning Disabilities

    Science.gov (United States)

    Singleton, Sabrina M.; Filce, Hollie Gabler

    2015-01-01

    Research suggests students with learning disabilities often have trouble connecting new and prior knowledge, distinguishing essential and nonessential information, and applying comprehension strategies (DiCecco & Gleason, 2002; Vaughn & Edmonds, 2006). Graphic organizers have been suggested as tools educators can use to facilitate critical…

  9. Sansen for kirkens spir

    DEFF Research Database (Denmark)

    Böss, Michael

    2009-01-01

    Om religion og modernitet med henvisning til bøger af Karen Armstrong, Hans Jørgen Schanz og Marcel Proust. Udgivelsesdato: 26. december 2009......Om religion og modernitet med henvisning til bøger af Karen Armstrong, Hans Jørgen Schanz og Marcel Proust. Udgivelsesdato: 26. december 2009...

  10. Identification of a Major Locus Contributing to Erythrocyte 2,3-Diphosphoglycerate Variability in Hooded (Long-Evans) Rats

    Science.gov (United States)

    Noble, N. A.; Brewer, G. J.

    1977-01-01

    The erythrocyte glycolytic intermediate 2,3-diphosphoglycerate (DPG) and adenosine triphosphate (ATP) play an important role in oxygen transport and delivery by binding to hemoglobin (Hb) and reducing its affinity for oxygen. Considerable quantitative variability in the levels of DPG and ATP exists in human populations and in a population of hooded (Long-Evans) rats we have studied. This paper presents the results of studies on the genetic component of DPG-level variation in an outbred population of hooded rats. Beginning with about 100 rats, a two-way selection experiment was initiated. Pairs of rats with the highest DPG levels were mated to produce a High-DPG rat strain and animals with the lowest DPG levels were mated to produce a Low-DPG strain. Mean DPG levels responded rapidly to selection and, from generation 3 on, the differences between strain means were highly significant. Ten High-DPG strain rats were intercrossed with 10 Low-DPG strain rats of generation 10 to produce an F1 generation in which the DPG levels were almost as high as those of High-DPG animals. This indicates partial dominance of High-DPG alleles. The F2 DPG-level distribution showed two distinct subpopulations. The high DPG subpopulation contained three times as many animals as the low DPG subpopulation. From these results and the statistical analyses performed, it was concluded that the DPG differences between strains were due to an allelic difference at one major locus, the allele carried by the High-DPG strain showing partial dominance over the allele carried by the Low-DPG strain. It appears that this locus may also effect ATP levels to a large extent and is polymorphic in hooded rat populations. Identification of this locus gives us a useful tool for studies of the physiological effects of DPG variability, as well as providing an example of a major gene effect in a quantitatively varying trait. PMID:863239

  11. Curricular Pillars in the Elementary General Music Classroom

    Science.gov (United States)

    Howell, Allen C.

    2009-01-01

    Karen, a veteran elementary general music teacher, was bewildered when she learned that none of her students remembered "Peter and the Wolf," a music lesson they have encountered in the past. Conscientious beginning elementary general music teachers like Karen may work diligently to plan instruction that will ensure that national, state, and local…

  12. Equal Educational Opportunity: Hearings Before the Select Committee on Equal Educational Opportunity of the United States Senate, Ninety-Second Congress, First Session on Equal Educational Opportunity. Part 19A--Equal Educational Opportunity in Michigan. Hearings Held Washington, D.C., Oct 26, and Nov 1-2, 1971.

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Senate Select Committee on Equal Educational Opportunity.

    Testimony was presented at these hearings by the following witnesses: Ronald Edmonds, assistant superintendent, School and Community Affairs, Michigan Department of Education; Dr. Daniel H. Kruger, professor, School of Labor and Industrial Relations, Michigan State University; Robert McKerr, associate superintendent, Business and Finance, Michigan…

  13. On our need to move beyond folk medicine: A commentary on Karen Gubb's paper, "Psychosomatics today: a review of contemporary theory and practice".

    Science.gov (United States)

    Gottlieb, Richard M

    2013-02-01

    In her thoughtful review and synthesis, Karen Gubb overstimates the breadth of resurgent interest among psychoanalysts in psychosomatic medicine. Such a modest revival as there has been reflects primarily the activity of a few authors and editors. Still, after several decades of inactivity following the intense excitement about this subject during the 1940s and 1950s, there has been some renewal of interest, primarily in Europe and among a small group in the United States. The golden age of psychoanalytic psychosomatics came to an end with the failure to find evidence in support of the promising but overly simplistic specificity theories, especially those of Franz Alexander. If we were going to better understand the complex relations between bodily states (including illnesses) and mental phenomena new theories and modes of investigation would be required. Many apparently new theories have been put forward over the past few decades. Of these, Gubb focuses her attention on two that relate somatic illness to failures in linguistic or symbolic elaboration, that is, to failures in the working over or binding of somatic excitations by the mental apparatus. These theories share the attractive feature that they seem consistent with the claim that psychosomatically ill patients are impaired in their language capacities, being unable to put feelings into words (alexithymia) and unable to move to abstract from concrete thinking (pensée opératoire). While apparently new, when closely examined these theories turn out to be but minor variations of one of Freud's own fundamental theories of mind/body, the one explicated in The Interpretation of Dreams and based upon the neurological model of the reflex arc as known in the 19th century. We know too much today about neuronal functioning, brain operations, and the importance of our subtle interactions with others to be satisfied with a superannuated scientific model. If we analysts are to lay claim to a science beyond a quaint

  14. Dietary isoflavones alter regulatory behaviors, metabolic hormones and neuroendocrine function in Long-Evans male rats

    Directory of Open Access Journals (Sweden)

    Bu Lihong

    2004-12-01

    Full Text Available Abstract Background Phytoestrogens derived from soy foods (or isoflavones have received prevalent usage due to their 'health benefits' of decreasing: a age-related diseases, b hormone-dependent cancers and c postmenopausal symptoms. However, little is known about the influence of dietary phytoestrogens on regulatory behaviors, such as food and water intake, metabolic hormones and neuroendocrine parameters. This study examined important hormonal and metabolic health issues by testing the hypotheses that dietary soy-derived isoflavones influence: 1 body weight and adipose deposition, 2 food and water intake, 3 metabolic hormones (i.e., leptin, insulin, T3 and glucose levels, 4 brain neuropeptide Y (NPY levels, 5 heat production [in brown adipose tissue (BAT quantifying uncoupling protein (UCP-1 mRNA levels] and 6 core body temperature. Methods This was accomplished by conducting longitudinal studies where male Long-Evans rats were exposed (from conception to time of testing or tissue collection to a diet rich in isoflavones (at 600 micrograms/gram of diet or 600 ppm vs. a diet low in isoflavones (at approximately 10–15 micrograms/gram of diet or 10–15 ppm. Body, white adipose tissue and food intake were measured in grams and water intake in milliliters. The hormones (leptin, insulin, T3, glucose and NPY were quantified by radioimmunoassays (RIA. BAT UCP-1 mRNA levels were quantified by PCR and polyacrylamide gel electrophoresis while core body temperatures were recorded by radio telemetry. The data were tested by analysis of variance (ANOVA (or where appropriate by repeated measures. Results Body and adipose tissue weights were decreased in Phyto-600 vs. Phyto-free fed rats. Food and water intake was greater in Phyto-600 animals, that displayed higher hypothalamic (NPY concentrations, but lower plasma leptin and insulin levels, vs. Phyto-free fed males. Higher thyroid levels (and a tendency for higher glucose levels and increased uncoupling

  15. Résultats de recherche | Page 17 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... ventes de l'entreprise Karen Coffee entraînent des répercussions sociales. Trente pour cent du profit net provenant des ventes de la Karen Coffee est remis aux groupes de femmes situés à Than Daung Gyi. Date de publication. 18 décembre 2017. Nouvelle. Information and Communication JOURNALISM JOURNALISTS ...

  16. Rootsi saamid võitlevad õiguse eest maale / Sarah Edmonds

    Index Scriptorium Estoniae

    Edmonds, Sarah

    2007-01-01

    Rootsi saamide parlamendil on 1. jaanuarist õigus määrata kohalikud piirid ja jagada abiraha loomasööda ostmiseks ja kompensatsioonide maksmiseks. Nüüd soovivad saamid maaga seotud küsimuste lahendamist. Lisa: Rootsi tõrjub põlisasukate konventsiooni

  17. Horticulture Therapy Curriculum Development. Final Report.

    Science.gov (United States)

    Taylor, Sally; And Others

    This final report includes two major components: a narrative describing a project at Edmonds Community College, Washington, to develop a horticultural therapy curriculum and descriptions of six courses developed or revised during the project. The narrative reports the development of a supplementary interdisciplinary certification program to train…

  18. Inactivating the infralimbic but not prelimbic medial prefrontal cortex facilitates the extinction of appetitive Pavlovian conditioning in Long-Evans rats.

    Science.gov (United States)

    Mendoza, J; Sanio, C; Chaudhri, N

    2015-02-01

    The infralimbic medial prefrontal cortex (IL) has been posited as a common node in distinct neural circuits that mediate the extinction of appetitive and aversive conditioning. However, appetitive extinction is typically assessed using instrumental conditioning procedures, whereas the extinction of aversive conditioning is customarily studied using Pavlovian assays. The role of the IL in the extinction of appetitive Pavlovian conditioning remains underexplored. We investigated the involvement of the IL and prelimbic medial prefrontal cortex (PrL) in appetitive extinction in Pavlovian and instrumental conditioning assays in male, Long-Evans rats. Following acquisition, a gamma-aminobutyric acid agonist solution (0.03 nmol muscimol; 0.3 nmol baclofen; 0.3 μl/side) was bilaterally microinfused into the IL or PrL to pharmacologically inactivate each region before the first extinction session. Compared to saline, PrL inactivation did not affect the acquisition of extinction or the recall of extinction memory 24-h later. IL inactivation caused a more rapid extinction of Pavlovian conditioning, but had no effect on the extinction of instrumental conditioning or extinction recall. IL inactivation during a Pavlovian conditioning session in which conditioned stimulus (CS) trials were paired with sucrose did not affect CS-elicited behaviour, but increased responding during intervals that did not contain the CS. The same manipulation did not impact lever pressing for sucrose. These findings suggest that the IL may normally maintain Pavlovian conditioned responding when an anticipated appetitive CS is unexpectedly withheld, and that this region has distinct roles in the expression of Pavlovian conditioning when an appetitive unconditioned stimulus is either presented or omitted. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. Eestit esindab Venezia biennaalil 21. sajandi eramute kõrgmood / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2010-01-01

    27. augustil avatakse 12. Venezia arhitektuuribiennaalil "Inimesed kohtuvad arhitektuuris" (üldkuraator Kazuyo Sejima) Eesti väljapanek "100 maja / houses", mille komissar on Ülar Mark, kuraator Karen Jagodin, autorid Kalle Vellevoog, Tiiu Truus, Martin Pedanik ja Karen Jagodin. Lisaks 21. sajandi eramutele on ekspositsiooni lisatud valik ikoonilise tähendusega eramuid esimese Eesti Vabariigi ja nõukogude ajast

  20. 09 Marais WEB 02.pmd

    African Journals Online (AJOL)

    Owner

    Blixen lived on the farm where she had her coffee plantation has become a popular ... Blixen as the author of Out of Africa, which was catapulted into global fame ... story about white people living in modern-day Kenya, “Baroness Blixen has .... The Karen Blixen House Museum is situated in the upper market suburb of Karen.

  1. Revision of the Dysmorphoptilidae (Hemiptera: Cicadomorpha: Prosboloidea) of the Queensland Triassic-Part 2.

    Science.gov (United States)

    Lambkin, Kevin J

    2016-03-15

    The extinct hemipteran family Dysmorphoptilidae was a major component of the Triassic insect fauna of Queensland preserved at the Denmark Hill, Dinmore, Mount Crosby and Gayndah fossil insect sites. A total of 13 species have now been identified, of which eight species in five genera were examined in the first part of this revision. This second part revises the remaining five species in three genera. Eoscartoides Evans, 1956 (= Mesonirvana Evans, 1956, syn. nov.), comprising Eoscartoides bryani Evans, 1956 (= Mesonirvana abrupta Evans, 1956, syn. nov.) (Mount Crosby), Eoscartoides orthocladus (Tillyard, 1922) comb. nov. (Denmark Hill), and Eoscartoides dmitryi sp. nov. (Dinmore), is distinguished by a strongly developed arc-like strigil in the basal costal space, a very short stem of RA, and a deeply forked M1+2. The monotypic Eoscarterella Evans, 1956, with type species Eoscarterella media Evans, 1956 (Mount Crosby), has a strongly lobate tegmen with peculiar surface sculpture and M1+2 simple. Eoscartoides and Eoscarterella differ from most dysmorphoptilids in having more or less lobate tegmina with even margins (without the antero-apical emargination so typical of the family), as well as the early entry of RA1 into the costal margin and the associated extensive and antero-apically positioned RA2. These characters are also shared with two other dysmorphoptilids, the Australian Permian Belmontocarta Evans and an unnamed Triassic species from Kyrgyzstan, and the four thus form a distinct subgroup within the family. On the other hand, the monotypic Trifidella Evans, 1956 (= Alotrifidus Evans, 1956, syn. nov.), with type species Trifidella perfecta Evans, 1956 (= Alotrifidus interruptus Evans, 1956, syn. nov.) (Mount Crosby), is a more typical dysmorphoptilid with a distinct emargination, RA entering the margin much more apically, and RA2 of limited extent. Trifidella is presumably the sister of the Queensland Triassic Dysmorphoptiloides Evans, sharing the basal

  2. Mustvalge linnavilla / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2013-01-01

    Emil Urbeli ja Andrus Margi projekteeritud ning Kristiina Tuulbergi ja Jaanika Sokmani (Boreal OÜ) sisekujundusega villast Tallinnas. Kalle Pruuden on kujundanud baaripukid köögis ning sepispiirded treppidel. Aknakatted-riputussüsteemid ning padjad valmisid koostöös disainer Ange Saarega. Ehitusaeg: 2012 sügis. Elamispind: 454 m²

  3. 78 FR 300 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2013-01-03

    ... Bancshares, Inc., and thereby acquire control of First Commercial Bank, both of Edmond, Oklahoma. Board of... FEDERAL RESERVE SYSTEM Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company The notificants listed below have applied under the Change in Bank Control Act (12 U.S.C...

  4. Peru, People and Plants.

    Science.gov (United States)

    Thompson, Dennis

    Designed for horticulture, horticulture therapy, and botany students at Edmonds Community College (Washington), this 6-hour module explores the pre-Columbian use of plant materials in Peru and its relationships to cultural practices in modern Peru. The first sections provide basic information about the module, such as its objectives, the concepts…

  5. Changes in natriuretic peptides after acute hospital presentation for heart failure with preserved ejection fraction: A feasible surrogate trial endpoint? A report from the prospective Karen study.

    Science.gov (United States)

    Savarese, Gianluigi; Donal, Erwan; Hage, Camilla; Oger, Emmanuel; Persson, Hans; Daubert, Jean-Claude; Linde, Cecilia; Lund, Lars H

    2017-01-01

    In acute decompensated heart failure (ADHF) with preserved ejection fraction (HFpEF) there are no surrogate endpoints for early phase trials. The aim of the current study was to evaluate whether a reduction in natriuretic peptides (NP) between acute hospital presentation to stable follow-up is associated with improved mortality and morbidity. Patients presenting acutely to the hospital for ADHF with HFpEF enrolled in the Karolinska Rennes (KaRen) study and reporting N-terminal pro-B-type NP or B-type NP assessment at baseline hospital presentation and at 4-8weeks follow-up were prospectively studied. Logistic regression analyses were performed to detect the predictors of baseline and changes in NPs. Cox regression models were performed to assess the impact of NP reductions on mortality and the composite of mortality and HF hospitalization. Of 361 patients (median follow-up 585days), 267 (74%) reported an improvement in NPs, while 94 (26%) reported worsening. At baseline, the independent predictors of lower NPs were higher glomerular filtration rate (Odds Ratio [OR] per unit: 1.013; 95% Confidence Interval [CI]: 1.005-1.021) and younger age (OR per year: 0.972; CI: 0.947-0.998). Improvement in NPs at follow-up was predicted by higher heart rate at baseline (OR per bpm: 1.014; CI: 1.003-1.025). After adjustments, the hazard ratio for all-cause death was 0.730 (CI: 0.456-1.169) and for the composite outcome 0.814 (CI: 0.582-1.139) for patients who improved vs. worsened in NP levels. In patients presenting acutely to the hospital with HFPEF, an improvement in NP levels did not independently and significantly predict improved mortality and/or morbidity. NPs as surrogate endpoints in acute HFpEF require further study. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  6. Nutrition - Multiple Languages

    Science.gov (United States)

    ... Italiano) Japanese (日本語) Karen (S’gaw Karen) Kirundi (Rundi) Korean (한국어) Malay (Bahasa Malaysia) Nepali (नेपाली) Pashto (Pax̌tō / پښتو ) Portuguese (português) ... Agriculture MyPlate Icon - English HTML ... Center for Nutrition Policy and Promotion U.S. Department of Agriculture Malay (Bahasa Malaysia) Expand Section Choose MyPlate: 10 Tips to a ...

  7. Wall Street som kreationistisk forkynder

    DEFF Research Database (Denmark)

    Ekman, Susanne

    2016-01-01

    Artiklen gennemgår Karen Hos etnografi om Wall Street: "Liquidated: An ethnography of Wall Street" set i lyset af den offentlige debat vedrørende Goldman Sachs opkøb af Dong......Artiklen gennemgår Karen Hos etnografi om Wall Street: "Liquidated: An ethnography of Wall Street" set i lyset af den offentlige debat vedrørende Goldman Sachs opkøb af Dong...

  8. Chasseur de hadrons

    CERN Document Server

    Eytier, Jean-Louis

    2009-01-01

    Qu'aurait-il proposé comme solutions face aux déboires du LHC, le grand collisionneur du hadrons du CERN, arrêté peu après son démarrage à l'automne 2008? Lucien Edmond André Montanet était un des grands de la physique des particules. (2 pages)

  9. Nicotine and ethanol co-use in Long-Evans rats: Stimulatory effects of perinatal exposure to a fat-rich diet

    Science.gov (United States)

    Karatayev, Olga; Lukatskaya, Olga; Moon, Sang-Ho; Guo, Wei-Ran; Chen, Dan; Algava, Diane; Abedi, Susan; Leibowitz, Sarah F.

    2015-01-01

    Clinical studies demonstrate frequent co-existence of nicotine and alcohol abuse and suggest that this may result, in part, from the ready access to and intake of fat-rich diets. Whereas animal studies show that high-fat diet intake in adults can enhance the consumption of either nicotine or ethanol and that maternal consumption of a fat-rich diet during pregnancy increases operant responding for nicotine in offspring, little is known about the impact of dietary fat on the co-abuse of these two drugs. The goal of this study was to test in Long-Evans rats the effects of perinatal exposure to fat on the co-use of nicotine and ethanol, using a novel paradigm that involves simultaneous intravenous (IV) self-administration of these two drugs. Fat- vs. chow-exposed offspring were characterized and compared, first in terms of their nicotine self-administration behavior, then in terms of their nicotine/ethanol self-administration behavior, and lastly in terms of their self-administration of ethanol in the absence of nicotine. The results demonstrate that maternal consumption of fat compared to low-fat chow during gestation and lactation significantly stimulates nicotine self-administration during fixed-ratio testing. It also increases nicotine/ethanol self-administration during fixed-ratio and dose-response testing, with BEC elevated to 120 mg/dL, and causes an increase in breakpoint during progressive ratio testing. Of particular note is the finding that rats perinatally exposed to fat self-administer significantly more of the nicotine/ethanol mixture as compared to nicotine alone, an effect not evident in the chow-control rats. After removal of nicotine from the nicotine/ethanol mixture, this difference between the fat- and chow-exposed rats was lost, with both groups failing to acquire the self-administration of ethanol alone. Together, these findings suggest that perinatal exposure to a fat-rich diet, in addition to stimulating self-administration of nicotine, causes

  10. Ethnic Federalism, Fiscal reform, Development and Democracy in ...

    African Journals Online (AJOL)

    Ethnic Federalism, Fiscal reform, Development and Democracy in Ethiopia. Edmond J. Keller. Abstract. (Af. J. Political Science: 2001 7(1): 21-50). Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/ajps.v7i1.27323 · AJOL African Journals Online.

  11. El polisulfuro de calcio en el manejo de la moniliasis Moniliophthora roreri (Cif & Par. Evans et al. del cacao Theobroma cacao L.

    Directory of Open Access Journals (Sweden)

    Sandra Ramírez González

    2011-05-01

    Full Text Available El cacao es severamente afectado por el hongo Moniliophthora roreri (Cif & Par. Evans et al., el cual daña los frutos y puede ocasionar pérdidas totales y su control es principalmente cultural. El objetivo del trabajo es determinar la efectividad del polisulfuro de calcio (PC como alternativa para su manejo. El patógeno fue aislado y cultivado in vitro y se evaluó el efecto del PC sobre la germinación y formación de conidias; en el campo, sobre frutos se asperjó PC antes y después de la inoculación con M. roreri y se determinó la incidencia e índices de severidad interna y externa. En una plantación de cacao se asperjó PC y se determinó su incidencia y producción. El PC in vitro inhibió el crecimiento y la formación de conidias; la aplicación de PC antes o después de la inoculación artificial con M. roreri sobre frutos inhibe completamente el desarrollo de la enfermedad; con aspersiones de PC en plantaciones de cacao la incidencia de la enfermedad fue de 0,53%, mientras que fue de 21% con manejo cultural y del 69,6% con testigo de inoculación natural; la producción de cacao seco/año fue de un 90,6% más con PC que en el testigo de inoculación natural, por lo que resulta viable integrar PC en el manejo deM. roreri.

  12. Comparison of the enhancement of plasma glucose levels in type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats by oral administration of sucrose or maple syrup.

    Science.gov (United States)

    Nagai, Noriaki; Ito, Yoshimasa; Taga, Atsushi

    2013-01-01

    Maple syrup is used as a premium natural sweeter, and is known for being good for human health. In the present study, we investigate whether maple syrup is suitable as a sweetener in the management of type 2 diabetes using Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of type 2 diabetes mellitus. OLETF rats develop type 2 diabetes mellitus by 30 weeks of age, and 60-week-old OLETF rats show hyperglycemia and hypoinsulinemia via pancreatic β-cell dysfunction. The administration of sucrose or maple syrup following an OGT test increased plasma glucose (PG) levels in OLETF rats, but the enhancement in PG following the oral administration of maple syrup was lower than in the case of sucrose administration in both 30- and 60-week-old OLETF rats. Although, the insulin levels in 30-week-old OLETF rats also increased following the oral administration of sucrose or maple syrup, no increase in insulin levels was seen in 60-week-old OLETF rats following the oral administration of either sucrose or maple syrup. No significant differences were observed in insulin levels between sucrose- and maple syrup-administered OLETF rats at either 30 or 60 weeks of age. The present study strongly suggests that the maple syrup may have a lower glycemic index than sucrose, which may help in the prevention of type 2 diabetes.

  13. Taxonomía, zoogeografía y aspectos ecológicos de los cangrejos ermitaños de la familia Diogenidae (Crustacea: Decapoda: Anomura) del Pacífico mexicano /

    OpenAIRE

    Ayón Parente, Manuel sustentante.

    2009-01-01

     tesis que para obtener el grado de Doctor en Ciencias del Mar y Limnología, presenta Manuel Ayón Parente ; asesor Michel Edmond Hendrickx Reners. 465 páginas : ilustraciones. Doctorado en Ciencias del Mar y Limnología UNAM, Instituto de Ciencias del Mar y Limnología, 2009

  14. Matching theory

    CERN Document Server

    Plummer, MD

    1986-01-01

    This study of matching theory deals with bipartite matching, network flows, and presents fundamental results for the non-bipartite case. It goes on to study elementary bipartite graphs and elementary graphs in general. Further discussed are 2-matchings, general matching problems as linear programs, the Edmonds Matching Algorithm (and other algorithmic approaches), f-factors and vertex packing.

  15. Sinopse das espécies neotropicais do grupo brasiliensis do gênero Apenesia (Hymenoptera, Bethylidae Synopsis of neotropical species of brasiliensis group genus Apenesia (Hymenoptera, Bethylidae

    Directory of Open Access Journals (Sweden)

    Magno S Ramos

    2009-12-01

    Full Text Available São descritas e ilustradas Apenesia longa sp. nov., A. peccata sp. nov., A. magna sp. nov., A. permaxima sp. nov., A. perconcava sp. nov. e A. recta sp. nov. da região Neotropical. São adicionados dados novos de variações estruturais e distribuição geográfica de A. transversa Evans, 1963, A. spinipes Evans, 1969, A. tlahuicana Evans, 1963, A. triangula Azevedo & Batista, 2002, A. megaventris Azevedo & Batista, 2002, A. venezuelana Evans, 1963, A. acia Lanes & Azevedo, 2004 e A. ventosa Azevedo & Batista, 2002. Duas sinonímias novas são propostas: A. peruana Evans, 1963 como sinônimo junior de A. brasiliensis (Kieffer, 1910; A. subangulata Azevedo & Batista, 2002 como sinônimo junior de A. fulvicollis (Westwood, 1874, esta ultima considerada dentro ao grupo nitida. É fornecida uma chave de identificação para as espécies do grupo, baseada em machos.Apenesia longa sp. nov., A. peccata sp. nov., A. magna sp. nov., A. permaxima sp. nov., A. perconcava sp. nov., and A. recta sp. nov., from Neotropical region are described and illustrated. Additional material of A. transversa Evans, 1963, A. spinipes Evans, 1969, A. tlahuicana Evans, 1963, A. triangula Azevedo & Batista, 2002, A. megaventris Azevedo & Batista, 2002, A. venezuelana Evans, 1963, A. acia Lanes & Azevedo, 2004 and A. ventosa Azevedo & Batista, 2002 had their structural variations and known distribution broadened. Two new synonyms are proposed: A. peruana Evans, 1963 as junior synonym of A. brasiliensis (Kieffer, 1910; A. subangulata Azevedo & Batista, 2002 as junior synonym of A. fulvicollis (Westwood, 1874, and the latter considered in the nitida group. An identification key to species of the group based on males is provided.

  16. The bilingual Loch Ness Monster raises its non-asymmetric head again-or, why bother with such cumbersome notions as validity and reliability? Comments on Evans et al. (2000).

    Science.gov (United States)

    Paradis, Michel

    2003-12-01

    All of the experimental studies of the past 25 years combined and the meta-analyses of their findings have not advanced our knowledge of the lateralization of language in bilingual speakers one bit. We are left with a clutter of inherently uninterpretable contradictory results. Successive studies do not contribute a single brick to the edifice or a single piece to the puzzle-only more confusion. study is no exception. So far, there has been no demonstration of the validity of any experimental paradigm claiming to measure degree of language laterality in bilingual speakers. Experimentation is pointless unless the nature of what is alleged to be lateralized is clearly defined and the validity of the measures employed has been established. Because of the lack of validity of the paradigms used in bilingual laterality studies, experiments and meta-analyses of their findings cannot have any scientific significance. Like their predecessors, Evans et al. pay lip service to a number of methodological problems, but ignore their implications and simply carry on anyway. The authors ought to demonstrate, rather than assume, that degree of visual half-field advantage for single words corresponds to degree of lateralization of any component of language (even if only of words).

  17. A new species of Dermopristis Kearn, Whittington & Evans-Gowing, 2010 (Monogenea: Microbothriidae), with observations on associations between the gut diverticula and reproductive system and on the presence of denticles in the nasal fossae of the host Glaucostegus typus (Bennett) (Elasmobranchii: Rhinobatidae).

    Science.gov (United States)

    Whittington, Ian D; Kearn, Graham C

    2011-09-01

    Dermopristis cairae n. sp. (Monogenea: Microbothriidae) is described from the skin and possibly from the nasal fossae of the giant shovel-nosed ray Glaucostegus typus (Bennett). The new species is distinguished from D. paradoxus Kearn, Whittington & Evans-Gowing, 2010 by its larger size, body shape, lack of transverse ridges on the ventral surface and absence of a seminal receptacle. Extensive short gut branches lie dorsal to the testes and adjacent to the coiled region of the vas deferens and the oötype, possibly reflecting high metabolic demand in these areas. Denticles are present in the lining of the nasal fossae of G. typus, providing a firm substrate for the cement-based attachment of a microbothriid. However, confirmation that D. cairae inhabits the nasal fossae of G. typus is required.

  18. An iron-deficient diet stimulates the onset of the hepatitis due to hepatic copper deposition in the Long-Evans Cinnamon (LEC) rat

    Energy Technology Data Exchange (ETDEWEB)

    Sugawara, Naoki; Sugawara, Chieko [Sapporo Medical Univ. (Japan). Dept. of Public Health

    1999-09-01

    To study effects of dietary Cu and Fe levels on the onset of hepatitis in Long-Evans Cinnamon (LEC) rats, female rats (40 days old) were fed a semipurified diet containing 0.1 or 10 mg Cu/kg and 1.5 or 150 mg Fe/kg in a 2 x 2 factorial arrangement for 35 days. At 75 days after birth, LEC rats (+Cu-Fe) fed a Cu-sufficient but Fe-deficient diet (Cu, 10 mg/kg; Fe, 1.5 mg/kg) showed jaundice, with lethargy, anorexia, and malaise. The biochemical variables relating to liver function were significantly increased compared to three other groups, a Cu- and Fe-deficient (-Cu-Fe) group, a Cu-deficient but Fe-sufficient (-Cu+Fe) group, and a Cu and Fe sufficient (+Cu+Fe) group. Furthermore, the +Cu-Fe rat liver showed massive necrosis with huge nuclei. The other three groups presented no biochemical and histological findings of hepatitis. Hepatic Cu and metallothionein concentrations were 289 {+-} 87 (mean {+-} SD) {mu}g/g liver and 8.7 {+-} 1.8 mg/g liver, respectively, in the +Cu-Fe rats. However, in the +Cu+Fe group the values were 196 {+-} 28 {mu}g Cu/g liver and 10.8 {+-} 1.0 mg/g liver. Hepatic Fe deposition was not influenced significantly by the dietary Cu level. The +Cu-Fe group with jaundice showed the highest free Cu concentration in the liver among the four groups, but the hepatic free Fe concentration was similar to those in the -Cu+Fe and +Cu+Fe groups. Our results indicate that an Fe-deficient diet enhances the deposition of hepatic Cu due to increased absorption of Cu from the gastrointestinal tract. This deposition stimulated the onset of hepatitis. (orig.)

  19. Long term modeling of the links between economics, technical progress and environment: Evolution of approaches and new trends

    International Nuclear Information System (INIS)

    Edmonds, J.

    1992-10-01

    This paper examines the evolution of modeling on greenhouse as emissions. The paper briefly highlights the origins and early efforts to model greenhouse gas emissions, efforts subsequent to 1988, and the shape of the next generation of greenhouse gas emissions models. Particular emphasis is placed on the author's own contributions, including the Edmonds-Reilly Model and the second generation model

  20. Saint Louis Center for Sustainment of Trauma and Readiness Skills: A Collaborative Air Force-Civilian Trauma Skills Training Program

    Science.gov (United States)

    2016-05-19

    NUMBER 6. AUTHOR(S) Jason W. Grimm , Karen Johnson 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION...ABSTRACT SAR 18. NUMBER OF PAGES 5 19a. NAME OF RESPONSIBLE PERSON Jason Grimm a. REPORT U b. ABSTRACT U c. THIS PAGE U 19b... Grimm Karen Johns For correspo Vista at Gra J Emerg Nu 0099-1767 Published b http://dx.do ■ ■ • ■SAINT LOUIS CENTER FOR SUSTAINMENT OF TRAUMA AND

  1. Armenian visit

    CERN Multimedia

    2003-01-01

    During his visit to CERN on 4 July 2003, Karen Chshmaritian, Armenian Minister for Trade and Economic Development, toured the ATLAS experimental cavern and assembly hall. From left to right: Aram Kotzinian, from the international organization JINR from Dubna, Marzio Nessi from ATLAS, Karen Chshmaritian, Armenian Minister for Trade and Economic Development, Zohrab Mnatsakanian, Ambassador at the Permanent Mission of the Republic of Armenia to the United Nations in Geneva, Alexandre Sissakian, Vice-Director of JINR and Peter Jenni, ATLAS spokesman.

  2. Ten Good Reasons for the Use of the Tellurium-Centered Anderson-Evans Polyoxotungstate in Protein Crystallography.

    Science.gov (United States)

    Bijelic, Aleksandar; Rompel, Annette

    2017-06-20

    Protein crystallography represents at present the most productive and most widely used method to obtain structural information on target proteins and protein-ligand complexes within the atomic resolution range. The knowledge obtained in this way is essential for understanding the biology, chemistry, and biochemistry of proteins and their functions but also for the development of compounds of high pharmacological and medicinal interest. Here, we address the very central problem in protein crystallography: the unpredictability of the crystallization process. Obtaining protein crystals that diffract to high resolutions represents the essential step to perform any structural study by X-ray crystallography; however, this method still depends basically on trial and error making it a very time- and resource-consuming process. The use of additives is an established process to enable or improve the crystallization of proteins in order to obtain high quality crystals. Therefore, a more universal additive addressing a wider range of proteins is desirable as it would represent a huge advance in protein crystallography and at the same time drastically impact multiple research fields. This in turn could add an overall benefit for the entire society as it profits from the faster development of novel or improved drugs and from a deeper understanding of biological, biochemical, and pharmacological phenomena. With this aim in view, we have tested several compounds belonging to the emerging class of polyoxometalates (POMs) for their suitability as crystallization additives and revealed that the tellurium-centered Anderson-Evans polyoxotungstate [TeW 6 O 24 ] 6- (TEW) was the most suitable POM-archetype. After its first successful application as a crystallization additive, we repeatedly reported on TEW's positive effects on the crystallization behavior of proteins with a particular focus on the protein-TEW interactions. As electrostatic interactions are the main force for TEW binding

  3. Arhitektuurivõistlused 2007 / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Tulemused: Eesti Rahvusringhäälingu hoone arhitektuurse idee konkurss (I - E. Nobel), Paide kutsekeskkoolide uue hoonekompleksi arhitektuurivõistlus (I - M. Tüür, V. Tomiste, O. Kadarik, Kosmos), Prantsuse Lütseumi spordihoone ideekonkurss (I - T. Laigu, K. Ojaliiv, M. Rass, EMP A&I), Volta kvartali kutsutud osalejatega ideevõistlus (I - AW2 Arkkitehtit), aasta betoonehitis 2006 - Luku-Experdi büroohoone (H. Kesler), Eesti Vabadussõja võidusamba võistlus (I - R. Sternfeld, A. Laidre, K. Kiho, A. Savi), Tabasalu alevikukeskuse hoonestuse kutsutud osalejatega ideevõistlus (I - T. Laigu, K. Ojaliiv, QP Arhitektid), Tamsalu linna keskosa ruumilise planeerimise avalik arhitektuurivõistlus (I - T. Skolimowski, K. Süda, A. Vaher, R. Parve, ASE), Eesti Vabaõhumuuseumi külastuskeskuse, ennistuskoja Kanut ja Tallinna muuseumide ühishoidla arhitektuurse idee võistlus (I - S. Vallner, I. Peil), Patarei ja lennusadama ala mahulise planeerimise rahvusvaheline ideevõistlus (I - I. Lubjak, S. Laanjärv), parim puitehitis 2007 - eramu Kiili vallas (K. Tõra, A. Sokk, T. Peipman), Keila Tuula tee 5 planeeringu võistlus (I - A. Uogintas, M. Podagelyte, M. Cirtautas)

  4. Tamm ja Asi / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Näitus "Sisearhitektid Väino Tamm & Vello Asi" Eesti Arhitektuurimuuseumis kuni 2. IX. Kuna valminud objektidest ei ole enam ühtegi originaalkujul alles, on eksponeeritud võimalikult suurel hulgal valmimisjärgseid fotosid, millest enamiku on teinud Rein Vainküla

  5. Uued koolid 2006 / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Viimsi kool (arhitektid Illimar Truverk, Raul Järg, Priit Pent, Eero Endjärv; sisearhitektid Kristi Lents, Hannelore Pihlak), Rakvere eragümnaasiumi algklasside maja (arhitektid Laur Pihel, Tauno Aadma), Tallinna Rahumäe põhikool (arhitektid Maaja Nummert, Triinu Nurmik), Tabasalu Ühisgümnaasium (arhitekt Veljo Kaasik), Jüri gümnaasium (arhitekt Katrin Tomberg Tohter)

  6. Karen Blixen. The Devil's Advocate

    DEFF Research Database (Denmark)

    Bunch, Mads

    Denne Ph.d. er en artikel-Ph.d. og består af tre artikler, der er integreret i en længere baggrundssektion, der indeholder 1) en forskningsoversigt over Blixen Kierkegaard forskningen fra 1934 til i dag, 2) refleksioner over den teori og metode, der er anvendt i hver af artiklerne, 3) en række su...

  7. 2006. aasta arhitektuurikonkursid / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Toodud ka 2006. a. konkursside tulemused: Eesti Rahva Muuseumi uus hoone, Tartu Ida t. lastead, Kiviõli linnaväljak, Tartu Lutsu t. korterelamu fassaadilahendus, Paide spordihall, Pärnu piirivalvekordoni hoone, Tartu Rebase t. kortermajade kompleks, Viljandi Maagümnaasiumi juurdeehitus, Veneetsia X arhitektuuribiennaali Eesti kuraatorinäitus, betoonehitis 2005, Estonia Seltsi vana teatrimaja asukoha tähistamine, TTÜ uus raamatukogu, Maakri kvartali arhitektuurikonkursi I etapp, Viljandi Uku t. 1A Lidli kauplusehoone ja südalinna kvartali detailplaneering, Pärnu jõeäärse keskuse ideeplaneering, Karksi-Nuia keskväljak ja roheala, terasehitis 2006, Edela-Eesti loodus- ja keskkonnahariduskeskuse ehk ökomaja eskiisprojekt, puitehitis 2006

  8. Taxonomia de Bakeriella (Hymenoptera, Bethylidae da Bolívia Taxonomy of Bakeriella (Hymenoptera, Bethylidae from Bolivia

    Directory of Open Access Journals (Sweden)

    Celso O. Azevedo

    Full Text Available A fauna de Bakeriella da Bolívia é analisada taxonomicamente. Bakeriella bulbosa Azevedo & Moreira sp. nov., B. labans Azevedo & Moreira sp. nov., B. vicina Azevedo & Moreira sp. nov., B. absens Kawada & Azevedo sp. nov. e B. nuda Kawada & Azevedo sp. nov. são descritas e ilustradas. Novos registros geográficos e dados de variações de B. montivaga (Kieffer, 1910, B. reclusa (Evans, 1969, B. incompleta Azevedo, 1994, B. inca Evans, 1964, B. polita Evans, 1964, B. flavicornis Kieffer, 1910 e B. lata Kawada & Azevedo, 2003 são fornecidos.The Bakeriella fauna from Bolivia is taxonomically analyzed. Bakeriella bulbosa Azevedo & Moreira sp. nov., B. labans Azevedo & Moreira sp. nov., B. vicina Azevedo & Moreira sp. nov., B. absens Kawada & Azevedo sp. nov. and B. nuda Kawada & Azevedo sp. nov. are described and illustrated. New geographic records and variation data of B. montivaga (Kieffer, 1910, B. reclusa (Evans, 1969, B. incompleta Azevedo, 1994, B. inca Evans, 1964, B. polita Evans, 1964, B. flavicornis Kieffer, 1910 and B. lata Kawada & Azevedo, 2003 are provided.

  9. LoRad M IV with stereologic stereotactic system for breast screening and follow-up examinations

    International Nuclear Information System (INIS)

    1999-01-01

    The LoRad M IV mammography unit was assessed clinically by radiological staff at the West Suffolk Hospital Breast Screening Unit, Bury St Edmonds for screening and assessment, and at the South East Scotland Breast Screening Centre for screening only. A full technical assessment was made in September 1998 by Physics staff from KCARE at Bury St Edmonds. The unit was physically assessed as an assessment mammography unit. The physical checks indicated that the unit met the requirements of MDA/95/40 with the following notable exceptions: The x-ray tube current is less than 100 ma at 28 kV. The available range of mAs is less than the recommended levels. The 'preparation' delay is over 1 second. Exposures can be made with the cassette out of position. The magnification factor is less than 1.8 x. The lead equivalent should be marked on the protective screen. Some of these points of non compliance will have no relevance for some applications. It is necessary that prospective purchasers should be aware of them even though they are not reflected in adverse comment by the assessors

  10. Er Danmark virkelig dårligere til ligestilling end Burundi?

    DEFF Research Database (Denmark)

    Sjørup, Karen

    2016-01-01

    Danmark ligger ifølge den årlige Gender Gap Report under Rwanda og Burundi I ligestiling. Men kan det nu have sin rigtighed, spørger Karen Sjørup? Nej svarer hun, men derfor kan regeringen godt tage sig sammen......Danmark ligger ifølge den årlige Gender Gap Report under Rwanda og Burundi I ligestiling. Men kan det nu have sin rigtighed, spørger Karen Sjørup? Nej svarer hun, men derfor kan regeringen godt tage sig sammen...

  11. Dr Luigi Orlando, Dr Sergio Ceccuzzi, Dr. Armando Sbrana, Europa Metalli, Italy, Dr Albert Scherger, Member of KM Europa Metal AG, Osnabr ck, Germany, Prof. Filippo Menzinger, Scientific Attaché, Permanent Mission of Italy in Geneva

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    Photo 01: Dr Lyn Evans and Dr Luigi Orlando Photo 04: L. to r.: Dr Lyn Evans, Dr Luigi Orlando, Prof. Luciano Maiani and Prof. Filippo Menzinger Photo 06: L. to r.: Prof. Philippo Menzinger, Dr Armando Sbrana, Prof. Luciano Maiani, Dr Albert Scherger, Dr Lyn Evans, Dr Luigi Orlando, Dr Sergio Ceccuzzi, visiting the LHC superconducting magnet test hall, SM18

  12. Ultra-short pulse, ultra-high intensity laser improvement techniques for laser-driven quantum beam science

    International Nuclear Information System (INIS)

    Kiriyama, Hiromitsu; Kando, Masaki

    2014-01-01

    Recent development activities of the Quantum Beam Research Team in JAEA are reported. The downsized, petawatt and femtosecond pulse laser is described at first. The process of the system development and utilization effort of so-called J-KAREN is explained with its time and space control system. For high contrast, OPCPA (Optical Parametric Chirped Pulse Amplification) preamplifier is adopted by using the titanium-sapphire laser system in which only the seed light pulses can be amplified. In addition, high contrast is obtained by adopting the high energy seed light to the amplifier. The system configuration of J-KAREN laser is illustrated. Typical spectra with and without OPCPA, as well as the spectra with OPCPA adjustment and without one are shown. The result of the recompressed pulses is shown in which the pulse width of 29.5 femtoseconds is close to the theoretical limit. Considering the throughput of the pulse compressor is 64 percent it is possible to generate high power laser beam of about 600 terawatts. In the supplementary budget of 2012, it has been approved to cope with the aging or obsoleteness of the system and at the same time to further sophisticate the laser using system. The upgraded laser system is named as J-KAREN-P in which the repetition rate is improved and another booster amplifier is added to increase the power. The system configuration of J-KAREN-P after the upgrading is illustrated. (S. Funahashi)

  13. In vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged Long-Evans rats: relationship to spatial learning

    International Nuclear Information System (INIS)

    Gallagher, M.; Bizon, J.L.; Nicolle, M.M.

    1996-01-01

    Using in vitro autoradiography, we investigated [ 3 H]α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate, [ 3 H]kainate and [ 3 H]N-methyl-d-aspartate binding in two forebrain regions, the hippocampus and striatum, of young (four months of age) and aged (24-25 months of age) Long-Evans rats that had previously been tested for spatial learning ability in the Morris water maze. Although there was substantial preservation of binding in the aged rats, reductions in binding were present in the aged rats that were specific to ligand and anatomical region. In the hippocampus of aged rats, [ 3 H]α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate binding in CA1 and [ 3 H]kainate binding in CA3 were reduced. In contrast, N-methyl-d-aspartate binding was not significantly different between age groups. There was evidence of sprouting in the dentate gyrus molecular layer of aged rats, indicated by changes in the topography of [ 3 H]kainate binding. Binding density was analysed with respect to patch/matrix compartmentalization in the striatum. The most striking result was a large decrease in N-methyl-d-aspartate binding in aged rats that was not limited to any dorsal/ventral or patch/matrix area of the striatum. Additionally, [ 3 H]kainate binding in striatal matrix was modestly reduced in aged rats. Of these age effects, only N-methyl-d-aspartate binding in the striatum and [ 3 H]kainate binding in the CA3 region of the hippocampus were correlated with spatial learning, with lower binding in the aged rats associated with better spatial learning ability.Age-related alterations in ionotropic glutamate receptors differ with respect to the receptor subtype and anatomical region examined. The age effects were not neccessarily indicative of cognitive decline, as only two age-related binding changes were correlated with spatial learning. Interestingly, in these instances, lower binding in the aged rats was associated with preserved spatial learning, suggesting a compensatory reduction

  14. Development of Design Standards and Guidelines for Electromagnetic Compatibility and Lightning Protection for Spacecraft Utilizing Composite Materials

    Science.gov (United States)

    Camp, Dennis W.

    1997-01-01

    This final report presents information concerning technical accomplishments by Tec-Masters, Inc. (TMI) for this contract effort. This effort included the accomplishment and/or submission by TMI of the following items: (1) Literature Survey Report, Electrical Properties of Non-Metallic Composites by Mr. Hugh W. Denny; (2) Interim Report, Composite Materials - Conductivity, Shielding Effectiveness, and Current Carrying Capability by Mr. Ross W. Evans; (3) Fault Current Test Plan by Mr. Ross W. Evans (4) Fault Current Test Procedure by Mr. Ross W. Evans (5) Test Report, Fault Current Through Graphite Filament Reinforced Plastic, NASA CR-4774, Marshall Space Flight Center, Alabama, September 1996, by Mr. Ross W. Evans; (6) Test Plan, Lightning Effects on Composite Materials by Mr. Ross W. Evans; (7) Test Report, Lightning Effects on Composite Materials, NASA CR-4783, Marshall Space Flight Center, Alabama, February 1997, by Mr. Ross W. Evans; (8) Design Guidelines for Shielding Effectiveness, Current Carrying Capability, and the Enhancement of Conductivity of Composite Materials, NASA CR-4784, Marshall Space Flight Center, Alabama, September 1996, by Mr. Ross W. Evans. These items are not attached but are considered to be a part of this final report. Efforts on two additional items were accomplished at no increase in cost to NASA/MSFC. These items consisted of updating the 'MSFC EMC Design and Interference Control Handbook,' and revising the 'Design Guidelines for Shielding Effectiveness, Current Carrying Capability, and the Enhancement of Conductivity of Composite Materials.'

  15. High initiation and long duration of breastfeeding despite absence of early skin-to-skin contact in Karen refugees on the Thai-Myanmar border: a mixed methods study.

    Science.gov (United States)

    White, Adrienne L; Carrara, Verena I; Paw, Moo Kho; Malika; Dahbu, Colleypaw; Gross, Mechthild M; Stuetz, Wolfgang; Nosten, Francois H; McGready, Rose

    2012-12-13

    Early skin-to-skin contact (SSC) after birth is recommended as part of the United Nations Children's Fund (UNICEF) baby friendly health initiative to promote optimum breastfeeding. This paper reports rates of breastfeeding initiation and duration in a low resource environment, where early SSC is not practised, and explores views of pregnant women and midwives surrounding breastfeeding and swaddling. Data from records from a single hospital on the Thai-Myanmar border where refugee women gave birth during a one-year period (2010) were used to determine breastfeeding initiation rates and the time of the first breastfeed, and duration of breastfeeding of the previous alive child in multigravidae. Focus group discussions (FGD) were conducted to obtain information from pregnant women attending antenatal care about their intended or previous duration of breastfeeding and views on breastfeeding. Interviews with local midwives explored reasons for high rates of breastfeeding in this setting and the practice of newborn swaddling. Of 1404 live births in 2010 in Maela refugee camp there were 982 evaluable mother-newborn pairs, including 80 infants born before 37 weeks gestation. Initiation of breastfeeding within the first hour after birth and exclusive breastfeeding at discharge in term mother-newborn pairs was 91.2% (823/902) and 99.3% (896/902); and before 37 weeks gestation, 48.8% (39/80) and 98.8% (79/80). Reported duration of previous breastfeeding was 19 (range 2 to 72) months.During FGD all primigravidae (n = 17) intended to breastfeed and all multigravidae (n = 33) had previously breastfed; expected or previous duration of feeding was for more than one year or longer. The major theme identified during FGD was breastfeeding is "good". Women stated their intention to breastfeed with certainty. This certainty was echoed during the interviews with midwifery staff. SSC requires a delay in early swaddling that in Karen people, with animistic beliefs, could risk loss

  16. A high repetition rate transverse beam profile diagnostic for laser-plasma proton sources

    Science.gov (United States)

    Dover, Nicholas; Nishiuchi, Mamiko; Sakaki, Hironao; Kando, Masaki; Nishitani, Keita

    2016-10-01

    The recently upgraded J-KAREN-P laser can provide PW peak power and intensities approaching 1022 Wcm-2 at 0.1 Hz. Scaling of sheath acceleration to such high intensities predicts generation of protons to near 100 MeV, but changes in electron heating mechanisms may affect the emitted proton beam properties, such as divergence and pointing. High repetition rate simultaneous measurement of the transverse proton distribution and energy spectrum are therefore key to understanding and optimising the source. Recently plastic scintillators have been used to measure online proton beam transverse profiles, removing the need for time consuming post-processing. We are therefore developing a scintillator based transverse proton beam profile diagnostic for use in ion acceleration experiments using the J-KAREN-P laser. Differential filtering provides a coarse energy spectrum measurement, and time-gating allows differentiation of protons from other radiation. We will discuss the design and implementation of the diagnostic, as well as proof-of-principle results from initial experiments on the J-KAREN-P system demonstrating the measurement of sheath accelerated proton beams up to 20 MeV.

  17. Army Sustainment. Volume 43, Issue 1, January-February 2011

    Science.gov (United States)

    2011-02-01

    Virgin - ia. During the previous week, a team from the BCTCP- Camp Dodge (which was responsible for the unit’s prior CPOF...and Christine L. Holiday 32 Improving Training for Recruiters COL James H. Comish and Donald D. Copley, Jr. 34 Logistics Partnering Lessons CW2...Planning and Decision Cycle LTC Millicen A. Dill 16 Using Holiday Block Leave to Update Training Materials Donald D. Copley, Jr., and Rodney Edmond

  18. Relationship between acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and disturbance of intermediary metabolism in the Long-Evans rat

    Energy Technology Data Exchange (ETDEWEB)

    Fan, F. (Dept. of Pharmacology, Toxicology and Therapeutics, Univ. of Kansas Medical Center, Kansas City, KS (United States)); Rozman, K.K. (Section of Environmental Toxicology, GSF-Inst. fuer Toxikologie, Neuherberg (Germany))

    1994-12-01

    The aim of this study was to examine the acute toxicity of TCDD in a rat strain other than the Sprague-Dawley (S-D) rat. Doses for the biochemical study were selected based on an acute range-finding study, which indicated that Long-Evans (L-E) rats are somewhat less susceptible to TCDD toxicity than are S-D rats. Male L-E rats were dosed orally with 10, 20, 45, 67, 100 and 150 [mu]g/kg TCDD. Body weight and feed intake were dose-dependently decreased prior to killing of the animals. Eight days after dosing, animals were killed and tryptophan, total T[sub 4] (TT[sub 4]) and total T[sub 3] (TT[sub 3]) levels were determined in serum, whereas the activities of ethoxy-resorufin-O-deethylase (EROD), phosphoenolpyruvate carboxykinase (PEPCK), [gamma]-glutamyl transpeptidase ([gamma]-GT) and tryptophan 2,3-dioxygenase (TdO) were measured in liver. EROD activity was fully induced at all doses studied, indicating that as in S-D rats, Ah-receptor-mediated effects do not seem to play any major role in the acute toxicity of TCDD in this rat strain either. Hepatic PEPCK activity was dose-dependently decreased in a similar dose range as in S-D rats, indicating inhibition of gluconeogenesis. Feed intake was dose-dependently decreased as a result of a dose-dependent elevation in serum tryptophan levels, which in turn were related to reduced liver TdO activity. Hepatic [gamma]-GT activity was also dose-dependently reduced. However, unlike in S-D rats, these dose-responses occurred in a higher dose range than the reduction of PEPCK activity which appears to be the explanation for the decreased susceptibility of L-E rats to TCDD. Serum TT[sub 4] levels were significantly decreased at all doses, whereas the serum concentration of TT[sub 3] appeared unaffected. The results of this study suggest that subtle differences in the regulation of intermediary metabolism between these two strains of rats are responsible for strain differences in the susceptibility to TCDD. (orig.)

  19. Celestial marriage and earthly rents: interests and the prohibition of polygamy.

    Science.gov (United States)

    Anderson, G M; Tollison, R D

    1998-01-01

    Just prior to the Civil War, the US government set out on a relentless campaign to eliminate polygamy within the Mormon Church. This paper offers evidence that the political restrictions on the practice of polygamy were the result of rent seeking by potential beneficiaries of such laws (the Edmonds Act of 1882). Polygamy created benefits for women, but reduced the welfare of most men, in a time period when only adult males had the franchise.

  20. Institutional Corruption: A Fiduciary Theory

    OpenAIRE

    Newhouse, ME

    2014-01-01

    Dennis F. Thompson developed a theory of “institutional corruption” in order to explain a phenomenon that he believed the Congressional ethics rules failed to address: Congress’ systematic deviation from its proper purpose as a consequence — not merely of individual wrongdoing — but of the influence of several general systemic features of the legislative process. Researchers at Harvard University’s Edmond J. Safra Center for Ethics have recently deployed the language of institutional corrupti...

  1. 77 FR 6785 - Proposed Information Collection; Comment Request; List of Gear by Fisheries and Fishery...

    Science.gov (United States)

    2012-02-09

    ... to Paula N. Evans (301) 427-8557 or Paula.Evans@noaa.gov . SUPPLEMENTARY INFORMATION: I. Abstract... hours and cost) of the proposed collection of information; (c) ways to enhance the quality, utility, and...

  2. Abiotic versus biotic drivers of ocean pH variation under fast sea ice in McMurdo Sound, Antarctica.

    Directory of Open Access Journals (Sweden)

    Paul G Matson

    Full Text Available Ocean acidification is expected to have a major effect on the marine carbonate system over the next century, particularly in high latitude seas. Less appreciated is natural environmental variation within these systems, particularly in terms of pH, and how this natural variation may inform laboratory experiments. In this study, we deployed sensor-equipped moorings at 20 m depths at three locations in McMurdo Sound, comprising deep (bottom depth>200 m: Hut Point Peninsula and shallow environments (bottom depth ∼25 m: Cape Evans and New Harbor. Our sensors recorded high-frequency variation in pH (Hut Point and Cape Evans only, tide (Cape Evans and New Harbor, and water mass properties (temperature and salinity during spring and early summer 2011. These collective observations showed that (1 pH differed spatially both in terms of mean pH (Cape Evans: 8.009±0.015; Hut Point: 8.020±0.007 and range of pH (Cape Evans: 0.090; Hut Point: 0.036, and (2 pH was not related to the mixing of two water masses, suggesting that the observed pH variation is likely not driven by this abiotic process. Given the large daily fluctuation in pH at Cape Evans, we developed a simple mechanistic model to explore the potential for biotic processes--in this case algal photosynthesis--to increase pH by fixing carbon from the water column. For this model, we incorporated published photosynthetic parameters for the three dominant algal functional groups found at Cape Evans (benthic fleshy red macroalgae, crustose coralline algae, and sea ice algal communities to estimate oxygen produced/carbon fixed from the water column underneath fast sea ice and the resulting pH change. These results suggest that biotic processes may be a primary driver of pH variation observed under fast sea ice at Cape Evans and potentially at other shallow sites in McMurdo Sound.

  3. Abiotic versus biotic drivers of ocean pH variation under fast sea ice in McMurdo Sound, Antarctica.

    Science.gov (United States)

    Matson, Paul G; Washburn, Libe; Martz, Todd R; Hofmann, Gretchen E

    2014-01-01

    Ocean acidification is expected to have a major effect on the marine carbonate system over the next century, particularly in high latitude seas. Less appreciated is natural environmental variation within these systems, particularly in terms of pH, and how this natural variation may inform laboratory experiments. In this study, we deployed sensor-equipped moorings at 20 m depths at three locations in McMurdo Sound, comprising deep (bottom depth>200 m: Hut Point Peninsula) and shallow environments (bottom depth ∼25 m: Cape Evans and New Harbor). Our sensors recorded high-frequency variation in pH (Hut Point and Cape Evans only), tide (Cape Evans and New Harbor), and water mass properties (temperature and salinity) during spring and early summer 2011. These collective observations showed that (1) pH differed spatially both in terms of mean pH (Cape Evans: 8.009±0.015; Hut Point: 8.020±0.007) and range of pH (Cape Evans: 0.090; Hut Point: 0.036), and (2) pH was not related to the mixing of two water masses, suggesting that the observed pH variation is likely not driven by this abiotic process. Given the large daily fluctuation in pH at Cape Evans, we developed a simple mechanistic model to explore the potential for biotic processes--in this case algal photosynthesis--to increase pH by fixing carbon from the water column. For this model, we incorporated published photosynthetic parameters for the three dominant algal functional groups found at Cape Evans (benthic fleshy red macroalgae, crustose coralline algae, and sea ice algal communities) to estimate oxygen produced/carbon fixed from the water column underneath fast sea ice and the resulting pH change. These results suggest that biotic processes may be a primary driver of pH variation observed under fast sea ice at Cape Evans and potentially at other shallow sites in McMurdo Sound.

  4. Eesti Sisearhitektuur aastal 2007 / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2007-01-01

    Eesti Kultuurkapitali arhitektuuri sihtkapitali ja Eesti Sisearhitektide Liidu 2006. a. preemiate laureaatidest ja nominentidest: Viimsi Keskkoolist (ESLi ühiskondliku ruumi preemia, H. Pihlak, K. Lents), restoranidest "Gianni" (P. Lausmäe) ja "Vertigo" (J. Roos, A. Labi), Foorumi kaubanduskeskusest (H. Praks, M. Tammik), Vene teatrist (A. Oja, R. Luuk), Koger &Partnerid büroost Fahle majas (ESLi ajaloolise intrejööri preemia, L. A. Tork), Skype'i büroost (arhitektuuri sihtkapitali sisearhitektuuri preemia, T. Piirmets) ning Velvet Creative Alliance (ESLi büroointerjööri preemia (T. Aunre) Tallinnas, Koordi mõisa peahoonest (R. Vaiksoo, K. Aren), diivanikompletist "Black" (ESLi esemepreemia, T. Mang), valgustitest "Saturn" ja "Mr. Note" (T. Luisk), lambiseeriast "Taara" (J. Roos, A. Labi)

  5. Liiga palju raha / Karen Lowry Miller

    Index Scriptorium Estoniae

    Miller, Karen Lowry

    2003-01-01

    Ilmunud ka: Spekter (vene k.) nr. 2, lk. 20-23. Autor kirjeldab, kuidas investorid rahanappusest üleküllusesse sattunud maailmas pidevalt uusi investeerimisvõimalusi otsivad ja juhib tähelepanu investorite poolt tekitatud majandusbuumides peituvatele ohtudele. Kaart: Seebimullide maakaart. Diagrammid: Raha kasvab kiiremini; Ülemaailmselt liikuv kapital

  6. The effects of herbal composition Gambigyeongsinhwan (4) on hepatic steatosis and inflammation in Otsuka Long-Evans Tokushima fatty rats and HepG2 cells.

    Science.gov (United States)

    Yoon, Seolah; Kim, Jeongjun; Lee, Hyunghee; Lee, Haerim; Lim, Jonghoon; Yang, Heejeong; Shin, Soon Shik; Yoon, Michung

    2017-01-04

    Hepatic steatosis has risen rapidly in parallel with a dramatic increase in obesity. The aim of this study was to determine whether the herbal composition Gambigyeongsinhwan (4) (GGH(4)), composed of Curcuma longa L. (Zingiberaceae), Alnus japonica (Thunb.) Steud. (Betulaceae), and the fermented traditional Korean medicine Massa Medicata Fermentata, regulates hepatic steatosis and inflammation. The effects of GGH(4) on hepatic steatosis and inflammation in Otsuka Long-Evans Tokushima fatty (OLETF) rats and HepG2 cells were examined using Oil red O, hematoxylin and eosin, and toluidine blue staining, immunohistochemistry, quantitative real-time polymerase chain reaction, and peroxisome proliferator-activated receptor α (PPARα) transactivation assay. Administration of GGH(4) to OLETF rats improved hepatic steatosis and lowered serum levels of alanine transaminase, total cholesterol, triglycerides, and free fatty acids. GGH(4) increased mRNA levels of fatty acid oxidation enzymes (ACOX, HD, CPT-1, and MCAD) and decreased mRNA levels of lipogenesis genes (FAS, ACC1, C/EBPα, and SREBP-1c) in the liver of OLETF rats. In addition, infiltration of inflammatory cells and expression of inflammatory cytokines (CD68, TNFα, and MCP-1) in liver tissue were reduced by GGH(4). Treatment of HepG2 cells with a mixture of oleic acid and palmitoleic acid induced significant lipid accumulation, but GGH(4) inhibited lipid accumulation by regulating the expression of hepatic fatty acid oxidation and lipogenic genes. GGH(4) also increased PPARα reporter gene expression. These effects of GGH(4) were similar to those of the PPARα activator fenofibrate, whereas the PPARα antagonist GW6471 reversed the inhibitory effects of GGH(4) on lipid accumulation in HepG2 cells. These results suggest that GGH(4) inhibits obesity-induced hepatic steatosis and that this process may be mediated by regulation of the expression of PPARα target genes and lipogenic genes. GGH(4) also suppressed obesity

  7. Why it was natural for Henri Becquerel to discover natural radioactivity

    International Nuclear Information System (INIS)

    Barquins, M.

    2002-01-01

    This article presents the scientific saga of the Becquerel family. 4 generations of Becquerel Antoine-Cesar (1788-1878), Edmond (1820-1891), Henri (1852-1906) and Jean (1878-1953) were involved in scientific activities at the highest level. Henri was awarded the Nobel prize of physics (shared with Pierre and Marie Curie) in 1903 for the discovery of radioactivity. The author shows that the discovery of radioactivity was due to talent, family emulation, genetics and chance. (A.C.)

  8. Effect of ageing on survival of benthic diatom propagules

    Digital Repository Service at National Institute of Oceanography (India)

    Anil, A.C.; Mitbavkar, S.; De; Hegde, S.; De; Meher, S.S.; Banerjee, D.

    unfavorable for vegetative growth, many diatoms form resting stages to survive cell degradation or death (Anderson, 1975; Malone, 1980; Hargraves and French, 1983; Fryxell, 1990). Various external factors like availability of nutrients (N, P, Fe, Si.... 128, 497-508. 15 Lewis, J., Harris, A.S.D., Jones, K.J., Edmonds, R.L., 1999. Long-term survival of marine planktonic diatoms and dinoflagellates in stored sediment samples. J. Plank. Res. 21, 343- 354. Malone, T.C., 1980. Algal size. In...

  9. Fluctuating gravity of Earth’s core

    OpenAIRE

    Stevenson, David J.

    2012-01-01

    For centuries, we have known that Earth’s magnetic field varies with time. Edmond Halley (better known for his eponymous recurring comet) first recognized this time variation of magnetic compass needle direction and even offered a remarkable theory that required an intervening fluid between Earth’s solid outer shell and a hypothesized innermost solid core (1). For decades, consensus has emerged for an explanation of this time variation that depends on the dynamics of Earth’s liquid metallic o...

  10. Carbon Stars T. Lloyd Evans

    Indian Academy of Sciences (India)

    that the features used in estimating luminosities of ordinary giant stars are just those whose abundance ... This difference between the spectral energy distributions (SEDs) of CH stars and the. J stars, which belong to .... that the first group was binaries, as for the CH stars of the solar vicinity, while those of the second group ...

  11. The radioactivity of the Hercynian Vosges; La radioactivite des Vosges hercyniennes

    Energy Technology Data Exchange (ETDEWEB)

    Rothe, J.P. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Institut de Physique du Globe de Strasbourg, 67 (France)

    1957-07-01

    On november 22, 1950, in the course of the formal beginning of term ceremony, the University of Strasbourg was pleased to confer on Professor VENING-MEINESZ the degree of Doctor Honoris Causa. In his speech of acknowledgement, Professor VENING-MEINESZ paid tribute to the fact that his colleague, Edmond ROTHE, had created at Strasbourg a centre of radio-geological research and during his visit to the Institute of Terrestrial Physics, the scholar whom we are honouring today expressed an interest in the new measurements that I was able to show him. I am happy to offer to him in homage some results of a systematic study of radioactivity of the Hercynian Vosges. (author) [French] Le 22 novembre 1950, au cours de sa seance solennelle de rentree, l'Universite de Strasbourg avait la joie de decerner au professeur VENING-MEINESZ le grade de Docteur Honoris Causa. Dans son allocution de remerciements, le professeur VENING-MEINESZ voulait bien rappeler que son collegue Edmond ROTHE avait cree a Strasbourg un centre de recherches de radiogeologie; et vistant l'Institut de Physique du Globe, le savant que nous honorons aujourd'hui acceptait de s'interesser aux mesures nouvelles que je pus alors lui presenter. Je suis heureux de lui offrir en hommage quelques resultats d'une etude systematique de radioactivite des Vosges hercyniennes. (auteur)

  12. Rosmary Waldrop and Theories of Translation

    Directory of Open Access Journals (Sweden)

    Duffy Nikolai

    2012-07-01

    Full Text Available Since the 1960s, the German-born US-American poet, Rosmarie Waldrop, has translated over 40 different works, largely from French and German, including 14 volumes by the Jewish French-language writer, Edmond Jabès (Jabès was expelled from Egypt in 1956 during the Suez Crisis. In 2003, Waldrop was made a Chevalier des Arts et des Lettres by the French Government, and in 2008 she received the PEN Award for Poetry in Translation in 2008, for her translation of Ulf Stolterfoht’s book, Lingos I-IX. As well as practising translation, however, Waldrop has also written several significant essays which reflect on different theories of translation and their implications for practice. Much of these considerations are taken up with the question of the relation between translation and writing, of thinking the ways in which theories of writing might suggest the lines for developing a specific form of poetic practice.This essay provides an overview of Waldrop’s central thoughts on translation and contextualises these in relation to some of the major theories of literary translation. In the latter part of the essay, these ideas are developed in specific relation to Waldrop’s translations of the work of Edmond Jabès and to the notion of writing practice it suggests.

  13. The radioactivity of the Hercynian Vosges; La radioactivite des Vosges hercyniennes

    Energy Technology Data Exchange (ETDEWEB)

    Rothe, J P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Institut de Physique du Globe de Strasbourg, 67 (France)

    1957-07-01

    On november 22, 1950, in the course of the formal beginning of term ceremony, the University of Strasbourg was pleased to confer on Professor VENING-MEINESZ the degree of Doctor Honoris Causa. In his speech of acknowledgement, Professor VENING-MEINESZ paid tribute to the fact that his colleague, Edmond ROTHE, had created at Strasbourg a centre of radio-geological research and during his visit to the Institute of Terrestrial Physics, the scholar whom we are honouring today expressed an interest in the new measurements that I was able to show him. I am happy to offer to him in homage some results of a systematic study of radioactivity of the Hercynian Vosges. (author) [French] Le 22 novembre 1950, au cours de sa seance solennelle de rentree, l'Universite de Strasbourg avait la joie de decerner au professeur VENING-MEINESZ le grade de Docteur Honoris Causa. Dans son allocution de remerciements, le professeur VENING-MEINESZ voulait bien rappeler que son collegue Edmond ROTHE avait cree a Strasbourg un centre de recherches de radiogeologie; et vistant l'Institut de Physique du Globe, le savant que nous honorons aujourd'hui acceptait de s'interesser aux mesures nouvelles que je pus alors lui presenter. Je suis heureux de lui offrir en hommage quelques resultats d'une etude systematique de radioactivite des Vosges hercyniennes. (auteur)

  14. "What About the Next Generation That's Coming?": The Recontextualization of Mothering Post-Refugee Resettlement.

    Science.gov (United States)

    Hoffman, Sarah J; Robertson, Cheryl L; Tierney, Jessica Dockter

    The purpose of this analysis was to explore the recontextualization of mothering in Karen refugees from Burma. We collected ethnographic data over an 11-month period with a cohort of 12 Karen women postresettlement. Using Spradley's and tools of critical discourse analysis, we interpreted the migration narratives of women, in particular, experiences they shared as mothers. These narratives were grounded in the space of cultural difference; thus, we engaged hybridity as a theoretical frame. Findings reflect the negotiation of mothering practices within the norms, structures, and policies of the country of resettlement. We identified the spaces of transformation a woman constructed to usher change while sustaining a connection between herself, her culture, and her children.

  15. Chemistry of Blood Type

    Science.gov (United States)

    Coleman, William F.

    2005-01-01

    The molecule of December 2005 comes from the paper by Rose, Palcic and Evans on structural factors determining the blood type. The structure was previously reported by Palcic and Evans and is presented without the water molecule that is determined in the crystal structure.

  16. A computational study on the effect of fracture intrusion distance in three- and four-part trochanteric fractures treated with Gamma nail and sliding hip screw.

    Science.gov (United States)

    Goffin, Jérôme M; Pankaj, Pankaj; Simpson, A Hamish

    2014-01-01

    Using finite element analysis, the behaviors of the Gamma nail and the sliding hip screw (SHS) were compared in an osteoporotic bone model for the fixation of three- and four-part trochanteric fractures (31-A2 in the AO classification, types IV and V in Evans' classification). The size of the medial fragment was varied based on clinical data, and the case of a fractured greater trochanter was also considered. Our results showed that for Evans' type V stabilized with a Gamma nail and for Evans' types IV and V with the SHS, cancellous bone around the lag screw is susceptible to yielding, thus indicating a risk of cut-out. The volume of bone susceptible to yielding increases with an increase in size of the medial fragment. Conversely, Evans' type IV with a Gamma nail was not predicted to cut out. Our findings suggest that future clinical trials investigating fixation of unstable proximal fractures should include the size of the medial fragment and the integrity of the greater trochanter as covariables and be powered to evaluate whether intramedullary devices are superior to SHSs for Evans' type IV fractures and inferior/equivalent for type V. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  17. The Army Enlistment Decision: An Overview of the ARI Recruit Surveys, 1982 and 1983

    Science.gov (United States)

    1984-06-01

    Tom Evans, Deputy Director of Advertising and Sales Promotion at USAREC, was very helpful in providing topic areas and information on advertising and...at the US Army Recruiting Command (USAREC). COL Graf and Mr. Evans, Director and Deputy Director of Advertising and Sales Promotion at USAREC, were

  18. 75 FR 19647 - Agency Information Collection Activities; Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-04-15

    ... supporting documentation should be addressed to Karen Jagielski, Attorney, Division of Advertising Practices... submitted to: Office of Information and Regulatory Affairs, Office of Management and Budget, Attention: Desk...

  19. A trendy approach to education!

    CERN Document Server

    Alizée Dauvergne

    2010-01-01

    On 11 March, Lyn Evans, the LHC project leader, talked live to hundreds of students in Wales using the standard videoconference equipment available at CERN (see box below). The students were delighted with the presentation and obviously very much appreciated this modern means of communication with the Laboratory. A further lecture is planned for May.   Question time after the videoconference between Lyn Evans and 27 schools and colleges in Wales. The Welsh Video Network (WVN) is one of the most advanced videoconferencing networks in the world, comprising over 80 networked video studios throughout Wales. For the LHC lecture given by Lyn Evans, no fewer than 27 schools and colleges were connected live with CERN. “This was a lecture for A-level students”, says Lyn Evans. “I introduced CERN and spoke about the physics we are doing here and what we want to discover. I talked about antimatter, dark matter, etc.” The LHC lecture was part of the WVN lecture series...

  20. Retirement postponed!

    CERN Multimedia

    Joannah Caborn Wengler

    2012-01-01

    As the LHC celebrates a highly successful year so far, the world accelerator community is already looking ahead to the next collider. It has appointed a CERN past master of accelerator building to coordinate the development of future linear collider efforts.   Lyn Evans at SM-18. Lyn Evans, former LHC project leader, has just been appointed director of the new Linear Collider organisation which brings together the two existing linear collider programmes under one roof. “We will initially continue to work in parallel on both CLIC and the ILC,” says Evans. The two proposed accelerators have a number of elements in common, from the damping rings to the final focus systems. Both have very similar detector designs, with the exception of the data acquisition systems as the machines have very different time structures. “The technologies for the two accelerators are at very different levels of maturity,” summarises Evans. When the time comes to make t...

  1. Building bridges … and accelerators

    CERN Multimedia

    2009-01-01

    Lyn Evans, the LHC project leader, was awarded an honorary doctorate from the University of Geneva (UNIGE) to celebrate his role not just in building accelerators, but also in building bridges between nations. He was one of four notables honoured at the event on Friday 5 June, coinciding with the University’s 450th Anniversary. Lyn Evans arriving at the ceremony with Archbishop Desmond Tutu. "It was a big surprise when I found out I’d been nominated," recounts Evans, "but it was an even bigger surprise to find out with whom I’d been nominated". At the ceremony Evans was awarded the honorary doctorate along with three others: Archbishop Desmond Tutu, who was acclaimed for his fight against apartheid in South Africa, Mary Robinson, first woman president of Ireland and former United Nations’ high commissioner of human rights, and Pascal Lamy, Director-General of the World Trade Organization. The award ceremony, known as the �...

  2. Notas sinonímicas sobre Hesperiidae neotropicais, com descrições de novos gêneros, espécies e subespécies (Lepidoptera

    Directory of Open Access Journals (Sweden)

    Olaf H. H. Mielke

    1990-01-01

    Full Text Available Celaenorrhinus shema mercedensis, ssp. n. de La Mercede e Rio Colorado, Peru e Cochabamba, Bolívia; Phocides pialia intermedia, ssp. n. de Minas Gerais, Brasil; Corticea diamantina, sp. n. de Minas Gerais, Brasil; Artines tobiasi sp. n. de Minas Gerais, Brasil; Cymaenes albiventris albiventris, sp. n. do Maranhão, Brasil; Cymaenes albiventris capixaba, ssp. n. do Espirito Santo, Brasil; Papias cascatona, sp. n. de Minas Geras, Brasil; Lerema caraca, sp. n. de Minas Gerais e Espirito Santo, Brasil; Vettius ploetzii morretesi, ssp. n. do Paraná e Rio Grande do Sul, Brasil Propapias, gen. n., tipo: Rhinthon proximus Bell, 1934, única espécie incluída. Celaenorrhinus songoensis saroma Evans, 1952, comb. n.; Celaenorrhinus songoensis tonio Evans, 1952, comb. n. Lerema duroca duroca (Ploetz, 1883, comb. n. e sp. rev. Lerema duroca lenta Evans, 1955, stat. n. Eumesia eburones inornata (Bell, 1937, comb. n. e stat. n., Eprius veleda obrepta (Kivirikko, 1936, comb. n. e stat. n., Phocides zancleius 1932 syn. n. de Phocides pialia (Hewitson, 1857; Dalla eburones elna Evans, 1955 syn. n. de Eumesia eburones inornata (Bell, 1937; Staphylus holaphegges Dyar, 1913 syn. n. de Eprius veleda veleda (Godman, 1901; Eprius veleda palta Evans, 1955 syn. n. de Eprius veleda obrepta (Kivirikko, 1936; Lerema elgina Schaus, 1902 syn. n. de Lerema duroca duroca (Ploetz, 1883. Dalla Mabille, 1904 syn. n. de Eumesia Felder &. Felder, 1867, n. rev, Eumesiinae Felder & Felder, 1867, n. rev.Celaenorrhinus shema mercedensis, ssp. n. from La Merced and Rio Colorado, Peru, and Cochabamba, Bolívia; Phocides pialia intermedia, ssp. n. from Minas Gerais, Brazil; Corticea diamantina, sp. n. from Minas Gerais, Brazil; Artines tobiasi, sp. n. from Minas Gerais, Brazil; Cymaenes albiventris albiventris, sp. n. from Maranhão, Brazil; Cymaenes albiventris capixaba, ssp. n. from Espírito Santo, Brazil; Papias cascatona, sp. n. from Minas Gerais, Brazil; Lerema caraca, sp. n. from

  3. 78 FR 4830 - National Advisory Committee on Microbiological Criteria for Foods; Reestablishment

    Science.gov (United States)

    2013-01-23

    .../NACMCF/index.asp . FOR FURTHER INFORMATION CONTACT: Karen Thomas, Advisory Committee Specialist, U.S... Meat Inspection Act (FMIA), the Poultry Products Inspection Act (PPIA), and the Egg Products Inspection...

  4. Dynamic Written Corrective Feedback in Developmental Multilingual Writing Classes

    Science.gov (United States)

    Kurzer, Kendon

    2018-01-01

    This study investigated the role of dynamic written corrective feedback (DWCF; Evans, Hartshorn, McCollum, & Wolfersberger, 2010; Hartshorn & Evans, 2015; Hartshorn et al., 2010), a mode of providing specific, targeted, and individualized grammar feedback in developmental English as a second language (ESL) writing classes (pre-first year…

  5. Download this PDF file

    African Journals Online (AJOL)

    Costallat GL, Appenzeller S, Costallat LT. Evans syndrome and. Systemic Lupus Erythematosus: Clinical presentation and outcome of. Evans syndrome and Systemic Lupus Erythematosus: Clinical pres- entation and outcome: Joint Bone Spine. 2012 Jul;79(4):362-4. Epub. 2011 Sep 23. 8. Greenbaum, Joseph M. McMann, ...

  6. Plasma volume in acute hypoxia

    DEFF Research Database (Denmark)

    Poulsen, T D; Klausen, T; Richalet, J P

    1998-01-01

    Exposure to acute hypoxia is associated with changes in body fluid homeostasis and plasma volume (PV). This study compared a dye dilution technique using Evans' blue (PV[Evans']) with a carbon monoxide (CO) rebreathing method (PV[CO]) for measurements of PV in ten normal subjects at sea level...

  7. 75 FR 19426 - Sunshine Act Meetings of the Board of Directors; Notice

    Science.gov (United States)

    2010-04-14

    .... Levon Henry, Executive Director, DNA Peoples Legal Services, Window Rock. 5. Staff Updates--Karen... of self assessment comments and goals from 2009 Board Self-Assessment cycle. 4. Staff report on...

  8. Closing the gap between people and programs: lessons from ...

    African Journals Online (AJOL)

    Closing the gap between people and programs: lessons from implementation of social accountability for family planning and reproductive health in Uganda. Vicky Boydell, Stella Neema, Kelsey Wright, Karen Hardee ...

  9. Sobre el arte de los nuevos medios

    Directory of Open Access Journals (Sweden)

    Celia Rivoulet

    2013-09-01

    Full Text Available Las tecnologías de información y comunicación han transformado completamente las prácticas artísticas contemporáneas, modificando las nociones tradicionales de tiempo, autor, medio, soporte, obra, realidad y espectador, y dando lugar a un nuevo género artístico: el arte digital. El presente póster analiza sus principales características con base en el estudio de los textos de Edmond Couchot y Jean-Pierre Balpe.

  10. Pharmacognostic evaluation of the leaves of Dissotis rotundifolia ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-01-05

    Jan 5, 2009 ... Romania, pp.17-25. Evans WC (1996). Trease and Evans Pharmacognosy. WB Saunders. Ltd. London. 14th Ed. 119-159. Harborne JB (1992). Phytochemical methods. A guide to modern technique of plant analysis. Chapman and Hill, London, p. 279. Kokwaro JC (1976). Medicinal plants of East Africa.

  11. Annual progress and future plans of laser R and D group

    International Nuclear Information System (INIS)

    Sugiyama, Akira; Kiriyama, Hiromitsu; Ochi, Yoshihiro; Tanaka, Momoko; Nakai, Yoshiki; Sasao, Hajime; Tateno, Ryo; Okada, Hajime; Kosuge, Atsushi; Tsubouchi, Masaaki

    2010-01-01

    Main subjects of our group in this middle term program are upgrade of J-KAREN and TOPAZ laser systems. The J-KAREN achieves the potential for generating a peak power of 500 TW, and exceeds a contrast ratio of 10E10. The TOPAZ achieves pulse power of 15 J at a repetition rate of 0.1 Hz. We also started a development of laser system named QUADRA (Quality Ultra ADvanced RAdiation Source) in C-Phost program. The QUADRA system aims a high averaged short pulse laser pumped by high power LD at kHz-class repetition rate. This development is essential for the elemental technology for the other new laser systems in the next 5-year program of JAEA. (author)

  12. A Retrospective, Longitudinal, Claims-Based Comparison of Concomitant Diagnoses Between Individuals with and Without Down Syndrome.

    Science.gov (United States)

    Kong, Amanda M; Hurley, Dana; Evans, Kristin A; Brixner, Diana; Csoboth, Csilla; Visootsak, Jeannie

    2017-07-01

    Individuals with Down syndrome (DS) experience various comorbidities in excess of the prevalence seen among the non-DS population. However, the extent of the excess burden of comorbidities specifically within commercially and publicly insured DS populations aged Company, receives payment from Genentech to conduct research, including the research for this study. Truven Health Analytics also receives payment from other pharmaceutical companies to conduct research. Kong and Evans are employed by Truven Health Analytics. Csoboth is employed by Genentech. Brixner reports fees paid to the University of Utah by Truven Health Analytics on her behalf for work related to this study. Hurley reports fees from Genentech for work on this study and for work outside of this study. At the time of this study, Visootsak was employed by F. Hoffman-LaRoche Pharmaceuticals, parent company of Genentech. All authors, including those affiliated with the study sponsor, were involved in the design of the study, interpretation of the data, writing of the manuscript, and the decision to submit the manuscript for publication. Study concept and design were contributed by Kong, Hurley, and Brixner, along with Evans. Kong and Evans collected the data, and data interpretation was performed by Csoboth, Visootsak, Brixner, and Hurley, with assistance from Kong. The manuscript was written by Evans, Kong, Hurley, and Brixner and revised by Kong, Hurley, Evans, and Brixner, with assistance from Csoboth and Visootsak.

  13. Health Information in Burmese (myanma bhasa)

    Science.gov (United States)

    ... Thinking of Suicide - myanma bhasa (Burmese) MP3 National Suicide Prevention Lifeline What Is Mental ... Karen Chemical Dependency Taskforce of Minnesota Mood Disorders What Is Mental Distress - English PDF What Is ...

  14. Health Information in Swahili (Kiswahili)

    Science.gov (United States)

    ... Someone Thinking of Suicide - Kiswahili (Swahili) MP3 National Suicide Prevention Lifeline What Is Mental ... Karen Chemical Dependency Taskforce of Minnesota Mood Disorders What Is Mental Distress - English PDF What Is ...

  15. Military Culture. A Paradigm Shift?

    National Research Council Canada - National Science Library

    Dunivin, Karen

    1997-01-01

    In this study, Lt Col Karen O. Dunivin, USAF, examines social change in American military culture and explores the current struggle between the military's traditional and exclusionary combat, masculine-warrior (CMW...

  16. Therapeutic efficacy of sulfadoxine-pyrimethamine in uncomplicated ...

    African Journals Online (AJOL)

    Therapeutic efficacy of sulfadoxine-pyrimethamine in uncomplicated Plasmodium falciparum malaria 3 years after introduction in Mpumalanga. Aaron Mabuza, John Govere, David Durrheim, Nicros Mangomezulu, Barry Bredenkamp, Karen Barnes, Brian Sharp ...

  17. Trunnion Rod Microcrack Detection

    Science.gov (United States)

    2013-08-01

    Richard W. Haskins, Joseph A. Padula , and John E. Hite BACKGROUND: Post-tensioned rods are used to anchor spillway gates and transfer the forces...email: James.A.Evans@usace.army.mil). This technical note should be cited as follows: Evans, J. A., Haskins, R. W., Padula , J. A., and Hite, J. E. 2013

  18. Effect of aqueous seed extract of Nigella sativa on lead-induced ...

    African Journals Online (AJOL)

    It is used in the manufacture of batteries, metal products, paints and other domestic substances. This study investigated the effect of aqueous seed extract of Nigella sativa on leadinduced cerebral cortex toxicity in Long Evan's rats. Twenty five Long Evans rats divided into five groups of five animals were used for the study.

  19. ...Da ne sudimõ budete / Karen Drambjan

    Index Scriptorium Estoniae

    Drambjan, Karen

    2008-01-01

    Autor analüüsib, millised on võimaliku vene parteide kandidaadi Georgi Bõstrovi võimalused saada valituks Euroopa Parlamenti. Vt. ka Mihhail Petrov. Tjomna voda v oblatsehh, Vesti Dnja 2. juuni 2008 lk. 4

  20. Roostetav legomaja / Karen Jagodin ; kommenteerinud Laila Põdra

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2009-01-01

    Betoonelementidest eramu (267 m²) Tabasalus. Arhitekt Laila Põdra, insener Indrek Laul. Sisekujundus: Laila Põdra koos omanikega. Projekt: 2005-2007, valmis: 2008. Betoon on viimistluspinnaks ka interjööris. Läbivaks tooniks sise- ja välisviimistluses on roostepunane, teiseks põhitooniks on valge. Konkursil "Aasta Betoonehitis 2008" pälvis tellija eripreemia

  1. Karakteriga kodu / Karen Jagodin ; kommenteerinud Enn Rajasaar

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2009-01-01

    2008. aastal valminud 2-korruseline eramu Mähel. Arhitekt Enn Rajasaar. Sisearhitekt Aet Seire. Välisviimistluses on kombineeritud tumedat tellist ja heledat krohvi. Sisekujundust läbivad värvid punane ja must. Osa mööbliesemeid (raamatukapid, söögitoa laud) valmisid sisearhitekti erilahendusena

  2. Hoolega valitud värvilaik / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2009-01-01

    Korter Rannamõisas. Korteri on kujundanud omanik pereliikmetega, kellest üks on arhitekt Pelle-Sten Viiburg, kes kavandas ka köögilaua. Kolmetoaline korter muudeti kahetoaliseks. Põhiideeks oli tekitada monokroomne ruum, kus aktsendi looksid üksikud värvilised mööbliesemed

  3. Köök - meelte ateljee / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2008-01-01

    2008. a. valminud õppeköögist "Köök" Tallinnas Pikk t. 42. Sisekujundus: Indrek Kasela, Sikke Sumari (omanikud). Paekivi- ja punasetest tellistest seintega ruumi kaunistab moodne kunst. Skulpturaalse veini- ja raamaturiiuli on kavandanud Edith Karlson ja Flo Kasearu, lühtri autor on Anna Roomet

  4. Lektoranmodning for Karen Løth Sass, DMJX

    DEFF Research Database (Denmark)

    Sass, Karen

    2018-01-01

    Det gennemgående tema i min anmodning er forholdet og balancen mellem den induktive/deduktive tilgang i praksislæringen. Titlen på lektoranmodningen er min egen kække sloganisering over den tilgang jeg kan iagttage hos mig selv og medundervisere, når vi næsten undskyldende lover de studerende, at...

  5. 77 FR 15052 - Dataset Workshop-U.S. Billion Dollar Disasters Dataset (1980-2011): Assessing Dataset Strengths...

    Science.gov (United States)

    2012-03-14

    ..., located at 151 Patton Avenue, Asheville, North Carolina 28801. FOR FURTHER INFORMATION CONTACT: Adam Smith...-4183, Email: Adam.Smith@noaa.gov ) For RSVP responses, use the email address noted above ( Karen.L...

  6. Delays and care seeking behavior among tuberculosis patients in ...

    African Journals Online (AJOL)

    Delays and care seeking behavior among tuberculosis patients in Tigray of Northern Ethiopia. Mengiste M Mesfin, Tesfay W Tasew, Israel G Tareke, Yohannes T Kifle, Witten H Karen, Madeley J Richard ...

  7. Kas Merrillis õnnestub korrata New Yorgi börsi edu? / Matthew Goldstein, Emily Thornton

    Index Scriptorium Estoniae

    Goldstein, Matthew

    2007-01-01

    Juhivahetusest ja tulevikuperspektiividest Merill Lynchi investeerimispangas. Vt. samas: Mara Der Hovanesian. Miks mitte Larry Fink?; Karen Young. Kuldsed langevarjud. Lisa: Kui nad täna lahkuksid (kümne tuntud tippjuhi lahkumispaketid)

  8. South African Medical Journal - Vol 107, No 1 (2017)

    African Journals Online (AJOL)

    Editorial · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Jacqui Webster, Christelle Crickmore, Karen Charlton, Krisela Steyn, Edelweiss Wentzel-Viljoen, Pamela Naidoo, 20-21 ...

  9. Presidential Green Chemistry Challenge: 1998 Academic Award (Draths and Frost)

    Science.gov (United States)

    Presidential Green Chemistry Challenge 1998 award winners, Dr. Karen M. Draths and Professor John W. Frost, used benign, genetically engineered microbes and sugars (instead of benzene) to synthesize adipic acid and catechol.

  10. DFB component production at IHEP complete

    CERN Multimedia

    2007-01-01

    1. LHC project leader Lyn Evans receiving a model of a DFB from IHEP general director Nikolaj Tyurin.2. Collective photo of DFB celebration at IHEP. Participants from left: V. Sytchev, V. Benda, N. Tyurin, A. Zaytcev, L. Evans, A. Perin, R. van Weelderen, Ph. Trilhe, M. Genet, L. Tavian, Ph. Lebrun, A. Kleshov.

  11. It’s no miracle...

    CERN Multimedia

    CERN Bulletin

    2012-01-01

    “The LHC has been a huge effort over more than 15 years. It’s not always been easy but today it is performing so spectacularly well that the people who built it should be very proud.” Lyn Evans, head of the LHC project since its beginning and until its commissioning in 2011, shares his recollections with us on the day of the long-awaited discovery.   Lyn Evans, former head of the LHC project, in the LHC tunnel, 2008. While you were building the LHC, were you expecting it to perform so well? Lyn Evans: I knew that the machine had been beautifully designed and was being built extremely well – but I could not have expected that such wonderful results could be achieved in so little time. What are the reasons for such a good performance? Evans: The LHC was designed to really push the limits; I think that the machine has got more than 30 years of accumulated experience in its design. The fact is the LHC has already exceeded the design luminosity at the en...

  12. 75 FR 54116 - Application To Export Electric Energy; Powerex Corp

    Science.gov (United States)

    2010-09-03

    ..., Federal power marketing agencies, and other entities within the United States. The existing international... No. EA-171-C. Additional copies are to be filed directly with Mike MacDougal and Karen McDonald...

  13. ORIGINAL ARTICLES

    African Journals Online (AJOL)

    PYRIMETHAMINE. I UNCOMPLICATED l'LASMODIUM FA LCIPARUM r IALARIA 3 YEARS AFTER. I TRODUCTION IN. T A:PUMALANGA f uon Mabuza, John Govere, David Durrheim, Nicros . ngomezulu, Barry Bredenkamp, Karen Barnes, Brian ...

  14. Foundations of health psychology

    National Research Council Canada - National Science Library

    Friedman, Howard S; Silver, Roxane Cohen

    2007-01-01

    ... and Effective Treatment 9 Adjustment to Chronic Disease: Progress and Promise in Research Annette L. Stanton and Tracey A. Revenson 203 10 Aging and Health 234 Karen S. Rook, Susan T. Charles, and...

  15. Health Information in Kinyarwanda (Rwanda)

    Science.gov (United States)

    ... PDF Strong Family Relationships Can Prevent Alcohol and Drug Use Among Teens - Rwanda (Kinyarwanda) MP3 Karen Chemical Dependency Taskforce of Minnesota What Is Addiction? - English PDF What Is Addiction? - Rwanda (Kinyarwanda) PDF ...

  16. Jevgeni Jevstignejev daval solo na vilkahh / Oleg Peranov

    Index Scriptorium Estoniae

    Peranov, Oleg

    2005-01-01

    Muusikaline tragikomöödia "Talveõhtu Gagras" ("Zimni vetsher v Gagrah") : režissöör Karen Shahnazarov : osades Jevgeni Jevstignejev, Natalja Gundareva : Mosfilm, NSV Liit 1985. Tegijad meenutavad filmivõtteid

  17. Appropriate tools and methods for tropical microepidemiology: a ...

    African Journals Online (AJOL)

    Appropriate tools and methods for tropical microepidemiology: a case-study of malaria clustering in Ethiopia. Tedros A Ghebreyesus, Peter Byass, Karen H Witten, Asfaw Getachew, Mitiku Haile, Mekonnen Yohannes, Steven W Lindsay ...

  18. "Viimne reliikvia" ja "Valgus koordis" : žanrifilmist žanrifilmini / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2010-01-01

    Žanrifilmi mõistmisest, 1960-ndate žanriuuendustest. Kahest eesti žanrifilmist: "Viimne reliikvia" (1969) ja "Valgus Koordis" (1951). Artikli järjes kõrvutatakse "Viimset reliikviat" Paul-Eerik Rummo "Tuhkatriinumänguga" (Vanemuises 1969., lavastaja E. Hermaküla). Sarnaseid jooni ka "Viimse reliikvia" ja teiste žanrifilmidega, pikemalt filmidest: Kaljo Kiisa "Hullumeelsus" (1968), Christian-Jaque'i "Tulp-Fanfanil" (Prantsusmaa, 1951), Tony Richardsoni "Tom Jones" (Inglismaa, 1963), Edmond Keosajani "Tabamatud tasujad" (Venemaa, 1966), Vytaytas Žalakeviciuse "Keegi ei tahtnud surra" (Leedu, 1965), Arthur Penni "Bonnie ja Clyde"

  19. Dollar Summary of Federal Supply Classification and Service Category by Company, FY84, Part 6 (7540-9999).

    Science.gov (United States)

    1984-01-01

    NEW YORK ARMY BOOKS AND PAMPHLETS D TH 52 BELL HELICOPTER/TEXTRON TEXAS ARMY BOOKS AND PAMPHLETS I ’’ h:D e 8 2 BENDER MATTHEW & CO INC 0 IST...689 DE ROSS! & SON CO INC NEW JERSEY DLA OUTERWEAR WOMENS 37 EDMONDS & WILLIAMS MFG CO ALABAMA NAVY OUTERWEAR WOMENS 66 DLA OUTERWEAR WOMENS 52 STATE...CORP UN KINGDOM 0ILA FUEL OILS 14 001 CUMBERLAND OIL COMPAN. MAINE DLA FUEL OILS 203 CURTIS D C INC VIRGINIA OLA FUEL OILS 8,10 DAHLEN FARMERS ELEV N

  20. Topographic Anterograde and Retrograde Memory for Spatial ...

    African Journals Online (AJOL)

    The present study was on the effects of haloperidol injection on anterograde and retrograde topographic memories for spatial behaviours in Long Evan rats. Twelve Long Evan albino rats weighing 0.5 – 0.8 kg (6 males, 6 females) were used for the study. Complex Maze Box of 14 unit T Alley from the Royal Institute of ...

  1. Snegurotshkad, plast ja punalipud ERKI moeshõul / Triin Thalheim

    Index Scriptorium Estoniae

    Thalheim, Triin, 1982-

    2005-01-01

    Sõna ja pildiga tutvustatakse Vene Kultuurikeskuses ERKI moeshõul esitatud Vassilissa, Kirill Safonovi, Kati Ilvese, Anna Roometi, Marte Kisandi, Pille Jürisoo, Karen Milistveri, Piret Paali, Erikka Bahnseni, Mikko Seppä, Hao Zhangi kollektsioone

  2. 76 FR 3601 - Codex Alimentarius Commission: Meeting of the Codex Committee on Pesticide Residues

    Science.gov (United States)

    2011-01-20

    ..., women, and persons with disabilities, are aware of this notice, FSIS will announce it on-line through... their accounts. Done at Washington, DC, on January 12, 2011. Karen Stuck, U.S. Manager for Codex...

  3. Õudusfiktsiooni narratiivsed tehnikad / Andrus Org

    Index Scriptorium Estoniae

    Org, Andrus

    2008-01-01

    Pikemalt eesti õudusulmest ning Karen Orlau "Rannahiidsetest" ja Matt Barkeri teosest "Kuri onu ja väike laps". Artikkel sisaldab joonealuseid märkusi ja bibliograafiat. Allikas: Narrative Techniques in Horror Fiction, lk. 441

  4. Kirjanduslik orgia?! Tänan, ei! / Raul Sulbi

    Index Scriptorium Estoniae

    Sulbi, Raul

    2002-01-01

    Arkaadia järjejutt (juuni - august 2002, autorid Wimberg, Veiko Märka, Urmas Vadi, Jürgen Rooste, Aapo Ilves, Aarne Ruben, Matt Barker, Hedda Maurer, Ivar Sild, Karen Orlau, Indrek Hargla, Jan Kaus, Mehis Heinsaar)

  5. The septins

    National Research Council Canada - National Science Library

    Hall, Peter A; Russell, S.E. Hilary; Pringle, John R

    2008-01-01

    ... and Caenorhabditis elegans Christine M. Field, Amy Shaub Maddox, John R. Pringle and Karen Oegema 147 Section III Septins in mammals 169 Chapter 7 The genomics and regulation of the human septin genes S.E....

  6. South African Medical Journal - Vol 89, No 2 (1999)

    African Journals Online (AJOL)

    Validation of a food frequency questionnaire in older South Africans · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Karen E Charlton, Estelle V Lambert, 184-189 ...

  7. Group Grammar

    Science.gov (United States)

    Adams, Karen

    2015-01-01

    In this article Karen Adams demonstrates how to incorporate group grammar techniques into a classroom activity. In the activity, students practice using the target grammar to do something they naturally enjoy: learning about each other.

  8. Effectiveness of shortcourse quinine and singledose ...

    African Journals Online (AJOL)

    Effectiveness of shortcourse quinine and singledose sulfadoxinepyrimethamine in the treatment of Plasmodium falciparum malaria in Mpumalanga Province, South Africa. Eugene Athan, David N. Dürrheim, Karen Barnes, Nicros M. Mngomezulu, Aaron Mabuza, John Govere ...

  9. State of terror: women at risk

    OpenAIRE

    The Karen Women’s Organisation

    2008-01-01

    Two reports researched and written by the Karen Women’sOrganisation – Shattering Silences in 2004 and State ofTerror in 20071 – document the wide range of humanrights abuses against Burmese women and girls.

  10. 77 FR 6825 - NASA Advisory Council; Information Technology Infrastructure Committee; Meeting.

    Science.gov (United States)

    2012-02-09

    ...; Information Technology Infrastructure Committee; Meeting. AGENCY: National Aeronautics and Space... Information Technology Infrastructure Committee of the NASA Advisory Council. DATES: Wednesday, March 7, 2012... CONTACT: Ms. Karen Harper, Executive Secretary for the Information Technology Infrastructure Committee...

  11. Teater Varius & Co / Indrek G. Sarapuu

    Index Scriptorium Estoniae

    Sarapuu, Indrek G.

    1999-01-01

    Jazz-draama "Põud" Varius Teatri esituses, dramatiseerija ja lavastaja Heidi Sarapuu, muusika Villu Veski ansamblilt, tants Renee Nõmmikult, peaosas Haide Männamaa. Draama käsitleb taani kirjaniku Karen Blixeni elu Aafrika-perioodi. Esietend. 26. aprillil

  12. Monitoring White-backed Vultures Gyps africanus in the North West ...

    African Journals Online (AJOL)

    Campbell Murn

    Stellaland), South Africa. Dirk, Karen and Stefan van Stuyvenberg. Stellaland Raptor Project. e-mail: stuyvies@telkomsa.net. Introduction. We became involved with the ringing of birds in 2002 and started to ring raptors actively since 2003.

  13. 75 FR 60126 - Performance Review Board Members

    Science.gov (United States)

    2010-09-29

    .... Childress Kenneth Y. Choe Richard M. Church Frank D. Cipolloni H. Westley Clark Henry Claypool Norris W... L. Hurst Jeanne C. Ireland Karen E. Jackson Holli B. Jaffe John S. Jarman George E. Jenkins Alfred C...

  14. Alcoholism and Alcohol Abuse - Multiple Languages

    Science.gov (United States)

    ... PDF Strong Family Relationships Can Prevent Alcohol and Drug Use Among Teens - دری (Dari) MP3 Karen Chemical Dependency Taskforce of Minnesota What Is Addiction? - English PDF What Is Addiction? - دری (Dari) PDF ...

  15. Health Information in Dari (دری)

    Science.gov (United States)

    ... PDF Strong Family Relationships Can Prevent Alcohol and Drug Use Among Teens - دری (Dari) MP3 Karen Chemical Dependency Taskforce of Minnesota What Is Addiction? - English PDF What Is Addiction? - دری (Dari) PDF ...

  16. Scientific Results of Yoga for Health and Well-Being

    Medline Plus

    Full Text Available ... for: Natural Product Research Mind and Body Research Pain Research All Grant Information Training About Research Training ... yoga may benefit people with chronic low-back pain, a common and difficult-to-treat problem. (Karen ...

  17. Scientific Results of Yoga for Health and Well-Being

    Medline Plus

    Full Text Available ... and joints in certain yoga postures. (George Salem, Ph.D., University of Southern California) An overview of ... common and difficult-to-treat problem. (Karen Sherman, Ph.D., M.P.H., Group Health Research Institute) ...

  18. Blixeni romaani põhjal tehtud filmis on Aafrika loodusel tegelase roll / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2006-01-01

    Mängufilm "Minu Aafrika" ("Out of Africa") taani kirjaniku Karen Blixeni elulooraamatu "Aafrika äärel" ainetel : režissöör Sidney Pollack : osades Meryl Streep, Robert Redford, Klaus Maria Brandauer : Ameerika Ühendriigid 1985

  19. A note on automorphisms of the sphere complex

    Indian Academy of Sciences (India)

    submit/ · 0607222 [math.GT], 4 Dec 20, accepted for publication in Rocky Mountain J. Math. [12] Vogtmann Karen, Automorphisms of free groups and outer space, Proceedings of the. Conference on Geometric and Combinatorial Group Theory, ...

  20. South African Journal of Animal Science - Vol 16, No 4 (1986)

    African Journals Online (AJOL)

    The effect of a dietary leucine excess on the immunoresponsiveness and growth of chickens · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Karen J. Tinker, RM Gous, 187-191 ...

  1. Karje kunstniku südamest / Kärt Hellerma

    Index Scriptorium Estoniae

    Hellerma, Kärt, 1956-

    1997-01-01

    Arvustus: Dinesen, Isak [Blixen, Karen]. Babette'i pidusöök / tlk. Piret Peiker. Tallinn : Varrak, 1996. Ilmunud ka kogumikus: Hellerma, Kärt. Kohanenud kirjandus : valik kirjanduskriitikat 1987-2006. Eesti Keele Sihtasutus : Tallinn, 2006. Lk. 167-169

  2. 75 FR 10206 - Codex Alimentarius Commission: Meeting of the Codex Committee on Contaminants in Food

    Science.gov (United States)

    2010-03-05

    ..., in an effort to ensure that minorities, women, and persons with disabilities are aware of this notice... March 1, 2010. Karen Stuck, U.S. Manager for Codex Alimentarius. [FR Doc. 2010-4694 Filed 3-4-10; 8:45...

  3. African Health Sciences - Vol 3, No 2 (2003)

    African Journals Online (AJOL)

    Effect of chloroquine on human immunodeficiency virus (HIV) vertical transmission · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Michael Neely, Israel Kalyesubula, Danstan Bagenda, Carolyn Myers, Karen Olness, 61-67 ...

  4. Responses of selected biota after biostimulation of a vegetable oil ...

    African Journals Online (AJOL)

    Responses of selected biota after biostimulation of a vegetable oil spill in the Con Joubert Bird Sanctuary wetland: A pilot study. Mapurunyane C Selala, Paul J Oberholster, Karen AK Surridge, Arno R de Klerk, Anna-Maria Botha ...

  5. State of terror: women at risk

    Directory of Open Access Journals (Sweden)

    The Karen Women’s Organisation

    2008-04-01

    Full Text Available Two reports researched and written by the Karen Women’sOrganisation – Shattering Silences in 2004 and State ofTerror in 20071 – document the wide range of humanrights abuses against Burmese women and girls.

  6. Asthma & Physical Activity in the School

    Science.gov (United States)

    Asthma & Physical Activity in the School MAKING A DIFFERENCE Asthma & Physical Activity in the School MAKING A DIFFERENCE Min: 5/ ... D. Chair, NAEPP School Subcommittee Working Group on Physical Activity and School American Medical Association Karen Huss, Ph. ...

  7. Edgewood Biosensors Test Bed Hand-held and Man-Portable Edition

    Science.gov (United States)

    2013-09-01

    CORPORATION, INC. Gunpowder, MD 21010-0068 Evan Skowronski TMG BIOSCIENCES Incline Village, NV 89451 September 2013 Approved for public release...Emanuel, Peter (ECBC); Rivers, Bryan; Schaffer, Eric (SAIC); and Skowronski, Evan ( TMG Biosciences) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK...21010-0068 TMG Biosciences, 774 Mays Blvd. #10-455, Incline Village, NV 89451 8. PERFORMING ORGANIZATION REPORT NUMBER ECBC-TR-1201 9

  8. Interservice/Industry Training, Simulation and Education Conference Partnerships for Learning in the New Millennium Abstracts

    Science.gov (United States)

    2000-01-01

    DISTRIBUTED POWER ARCHITECTURE John McCrillis, Kevin Cahill, Joseph Kerkes, Clint Steffan BAE SYSTEMS Flight Simulation and Training A typical full...DATABASE? Serge J. Olszanskyj Evans & Sutherland Computer Corporation We discuss the complexity of making a synthetic environment (i.e., a database...and architectures.This paper describes a DB conversion process jointly developed by Boeing, Westar, Evans and Sutherland (E&S), and Terrain Experts

  9. Wealth, equity and health care: a critique of a "population health" perspective on the determinants of health. Critical Social Science Group.

    Science.gov (United States)

    Poland, B; Coburn, D; Robertson, A; Eakin, J

    1998-04-01

    In this paper we examine the recent ascendancy of a "population health" perspective on the "determinants of health" in health policy circles as conceptualized by health economists and social epidemiologists such as Evans and Stoddart [Evans and Stoddart (1990) Producing health, consuming health care. Social Science & Medicine 31(12), 1347 1363]. Their view, that the financing of health care systems may actually be deleterious for the health status of populations by drawing attention away from the (economic) determinants of health, has arguably become the "core" of the discourse of "population health". While applauding the efforts of these and other members of the Canadian Institute for Advanced Research for "pushing the envelope", we nevertheless have misgivings about their conceptualization of both the "problem" and its "solutions", as well as about the implications of their perspective for policy. From our critique, we build an alternative point of view based on a political economy perspective. We point out that Evans and Stoddart's evidence is open to alternative interpretations--and, in fact, that their conclusions regarding the importance of wealth creation do not directly reflect the evidence presented, and are indicative of an oversimplified link between wealth and health. Their view also lacks an explicit substantive theory of society and of social change, and provides convenient cover for those who wish to dismantle the welfare state in the name of deficit reduction. Our alternative to the "provider dominance" theory of Evans and Stoddart and colleagues stresses that the factors or forces producing health status, which Evans and Stoddart describe, are contained within a larger whole (advanced industrial capitalism) which gives the parts their character and shapes their interrelationships. We contend that this alternative view better explains both how we arrived at a situation in which health care systems are as costly or extensive as they are, and suggests

  10. Kanepikasvatajate unine suvi / Jüri Ehlvest

    Index Scriptorium Estoniae

    Ehlvest, Jüri, 1967-2006

    2002-01-01

    Arkaadia järjejutust, ilmus juuni - august 2002 Eesti Päevalehes, autorid: Wimberg, Veiko Märka, Urmas Vadi, Jürgen Rooste, Aapo Ilves, Aarne Ruben, Matt Barker, Hedda Maurer, Ivar Sild, Karen Orlau, Indrek Hargla, Jan Kaus, Mehis Heinsaar

  11. 75 FR 3743 - Medicare Program; Meeting of the Practicing Physicians Advisory Council, March 8, 2010

    Science.gov (United States)

    2010-01-22

    ...; Fredrica E. Smith, M.D.; Richard E. Smith, M.D.; Arthur D. Snow, Jr., M.D.; Christopher J. Standaert, M.D.; and Karen S. Williams, M.D. II. Meeting Format and Agenda The meeting will commence with the Council's...

  12. Põlvkonnaromaan saksa nooremas kirjanduses / Peeter Helme

    Index Scriptorium Estoniae

    Helme, Peeter, 1978-

    2006-01-01

    Ülevaade järgmistest teostest: Christian Krachti "Faserland" (1995), Florian Illiesi ""Golfi" generatsioon" (2001), Annegret Kunkeli (tegel. Sophie Dannenberg) "Revolutsiooni pleekinud süda", Uwe Tellkampi "Jäälind", Karen Duve "See ei ole armastuslaul", Andreas Maieri "Kirillov"

  13. Autism Spectrum Disorders (ASD) and Diet

    Science.gov (United States)

    ... Conditions Autism Autism Spectrum Disorders (ASD) and Diet Autism Spectrum Disorders (ASD) and Diet By Karen Ansel, MS, RDN, CDN Published April 2, 2018 nambitomo/iStock/Thinkstock Autism Spectrum Disorder, or ASD, is a complex developmental and neurological ...

  14. African Journal of Reproductive Health - Vol 17, No 4 (2013)

    African Journals Online (AJOL)

    Risk Factors for Premature Births: A Cross-Sectional Analysis of Hospital Records in a Cameroonian Health Facility. Andreas Chiabi, Evelyn M Mah, Nicole Mvondo, Seraphin Nguefack, Lawrence Mbuagbaw, Karen K Kamga, Shiyuan Zhang, Emile Mboudou, Pierre F Tchokoteu, Elie Mbonda ...

  15. Tudengiprojekt

    Index Scriptorium Estoniae

    2009-01-01

    Eesti Kunstiakadeemia tootedisaini üliõpilase Siim Westi töö"Sõidukite arvutikontrolli süsteem". Nahakunsti üliõpilase Karen Milistveri helkur-kott "Morpho Peleides", mis jõudis 2008. a. Jaapanis toimunud rahvusvahelisel disainivõistlusel "Design for Happiness" auhinnanominentide hulka

  16. 78 FR 34393 - Electronic Submission of Tobacco Product Applications and Other Information; Public Workshop...

    Science.gov (United States)

    2013-06-07

    .... Contact Person: Karen M. Templeton-Somers, Office of Science, Center for Tobacco Products, Food and Drug... stakeholders and interested parties, including, but not limited to, large and small pharmaceutical..., large and small pharmaceutical manufacturers with experience in electronic submissions; vendors of...

  17. South African Medical Journal - Vol 107, No 12 (2017)

    African Journals Online (AJOL)

    The world's first human-to-human heart transplant at Groote Schuur Hospital: 50 years later · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Johan Brink, Tim Pennel, Karen Seele, Peter Zilla, 1035-1036 ...

  18. Risk Factors for Premature Births: A Cross-Sectional Analysis of ...

    African Journals Online (AJOL)

    Risk Factors for Premature Births: A Cross-Sectional Analysis of Hospital Records in a Cameroonian Health Facility. Andreas Chiabi, Evelyn M Mah, Nicole Mvondo, Seraphin Nguefack, Lawrence Mbuagbaw, Karen K Kamga, Shiyuan Zhang, Emile Mboudou, Pierre F Tchokoteu, Elie Mbonda ...

  19. South African Medical Journal - Vol 91, No 5 (2001)

    African Journals Online (AJOL)

    An outbreak of food poisoning among children attending an international sports event in Johannesburg - don't let it happen again! EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Karen H. Keddy, Hendrik J. Koornhof ...

  20. South African Journal of Education - Vol 38, No 1 (2018)

    African Journals Online (AJOL)

    Enabling the development of student teacher professional identity through vicarious learning during an educational excursion · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Karen Steenekamp, Martyn van der Merwe, Aygul Salieva Mehmedova ...

  1. Наше кино: из России с любовью / Борис Тух

    Index Scriptorium Estoniae

    Тух, Борис, 1946-

    2009-01-01

    Kriitik valib välja viis parimat Venemaa filmi 2009.a. Eestis näidatuist : "Meloodia väntorelile" (Kira Muratova, tegelikult Ukraina film), "Lõngused" (Valeri Todorovski), "Tsaar" (Pavel Lungin), "Palat nr. 6" (Karen Šahnazarov), "Kuumad uudised" (Anders Banke)

  2. R suite for the Reduction and Analysis of UFO Orbit Data

    Science.gov (United States)

    Campbell-Burns, P.; Kacerek, R.

    2016-02-01

    This paper presents work undertaken by UKMON to compile a suite of simple R scripts for the reduction and analysis of meteor data. The application of R in this context is by no means an original idea and there is no doubt that it has been used already in many reports to the IMO. However, we are unaware of any common libraries or shared resources available to the meteor community. By sharing our work we hope to stimulate interest and discussion. Graphs shown in this paper are illustrative and are based on current data from both EDMOND and UKMON.

  3. The problem with areas: Asia and Area studies

    Directory of Open Access Journals (Sweden)

    Victor T. King

    2012-09-01

    Full Text Available Review of:Goh Beng Lan (ed., Decentring & diversifying Southeast Asian Studies: Perspectives from the region. Singapore: ISEAS, 2011, xiii + 304 pp. ISBN 9789814311564, price: USD 34.90 (paperback; 9789814311571, USD 45.90 (hardback.Terence Wesley-Smith and Jon Goss (eds, Remaking Area studies: Teaching and learning across Asia and the Pacific. Honolulu: University of Hawai‘i Press, 2010, xxvii + 243 pp. ISBN 9780824833213. Price: USD 45.00 (hardback.Jacob Edmond, Henry Johnson and Jacqueline Leckie (eds, Recentring Asia: Histories, encounters, identities, xv + 339 pp. Leiden/Boston: Brill, Global Oriental: 2011. ISBN 9781906876258. Price: EUR 80.00 (hardback.

  4. Shifting Focus: Assessing the Role of U.S. Army Special Forces in the Counterproliferation of Weapons of Mass Destruction

    Science.gov (United States)

    2014-06-01

    would only further enhance this effect. An article in Foreign Policy by Gareth Evans describes cooperative security as the theory that explains the... Gareth Evans, “Cooperative Security and Intrastate Conflict,” Foreign Policy, no. 96 (Autumn 1994): 7. doi: 10.2307/1149213 20 John H. Herz...of the Oversight and Government Reform Committee, Brookings Institution Fellow Vanda Felbab- Brown discussed the effects of supply-side policies on

  5. Technical Evaluation of Sample-Processing, Collection, and Preservation Methods

    Science.gov (United States)

    2014-07-01

    Belcamp, MD 21017-1543 Bryan Rivers Eric Schaffer LEIDOS, INC. Gunpowder, MD 21010-0068 Evan Skrowronski TMG BIOSCIENCES, LLC Incline Village...Bryan; Schaffer, Eric (Leidos); and Skrowronski, Evan ( TMG Biosciences) 5d. PROJECT NUMBER R.0000061.61.41.1 5e. TASK NUMBER 5f. WORK UNIT...Leidos, Inc., P.O. Box 68, Gunpowder, MD 21010-0068 TMG Biosciences LLC, 774 Mays Blvd., Incline Village, NV 89451-9613 8. PERFORMING ORGANIZATION

  6. APOLLO 17 PRELAUNCH ASTRONAUT TRAINING

    Science.gov (United States)

    1972-01-01

    Apollo Command Module Pilot Evans, left, and Mission Commander Cernan, right, discuss their flight plans as each prepares to fly a T-38 jet aircraft at Patrick Air Force Base just south of the Spaceport. Astronauts Cernan and Evans flew the T-38 aircraft today on training flights over the Kennedy Space Center area to practice flying skills in preparation for upcoming launch to the Moon scheduled 12/06/72.

  7. Influence of obstetric complication severity on brain morphology in schizophrenia: an MR study

    Energy Technology Data Exchange (ETDEWEB)

    Bersani, G.; Quartini, A.; Manuali, G.; Iannitelli, A. [University of Rome, Polo Pontino, Department of Psychiatric Sciences and Psychological Medicine, Rome (Italy); Pucci, D. [University of Rome, Department of Public Health ' ' G. Sanarelli' ' , Rome (Italy); Conforti, F. [University of Rome, I Medical Clinic, Magnetic Resonance Imaging Unit, Rome (Italy); Di Biasi, C.; Gualdi, G.

    2009-06-15

    The purpose of this study was to determine if a causal relationship exists between obstetric complications (OCs) severity and linear magnetic resonance (MR) measurements of brain atrophy in patients with schizophrenia. Linear measurements of ventricular enlargement (bifrontal span, Evans ratio, and bicaudate ratio) and hippocampal atrophy (interuncal distance) were completed on MR images obtained in 47 patients with schizophrenia. Regression analysis was used to look at association with OCs severity, assessed by the ''Midwife protocol'' of Parnas and colleagues. The relationship between MR measurements and phenomenologic variables such as age at onset, illness duration, and exposure to antipsychotic medications was explored. The relationship between MR measurements, OCs severity, and symptom presentation was also investigated. OCs severity was significantly associated with MR measurements of ventricular enlargement (bifrontal span, Evans ratio). As the severity of OCs increased, bifrontal span and Evans ratio increased. This effect was independent of age at onset, illness duration, or even antipsychotic treatment. Interestingly, bifrontal span, Evans ratio, and OCs severity score all showed a significant positive correlation with hallucinatory symptomatology. Although confirmatory studies are needed, our findings would support the idea that environmental factors, in this case severe OCs, might partly contribute to ventricular abnormalities in schizophrenia. (orig.)

  8. Influence of obstetric complication severity on brain morphology in schizophrenia: an MR study

    International Nuclear Information System (INIS)

    Bersani, G.; Quartini, A.; Manuali, G.; Iannitelli, A.; Pucci, D.; Conforti, F.; Di Biasi, C.; Gualdi, G.

    2009-01-01

    The purpose of this study was to determine if a causal relationship exists between obstetric complications (OCs) severity and linear magnetic resonance (MR) measurements of brain atrophy in patients with schizophrenia. Linear measurements of ventricular enlargement (bifrontal span, Evans ratio, and bicaudate ratio) and hippocampal atrophy (interuncal distance) were completed on MR images obtained in 47 patients with schizophrenia. Regression analysis was used to look at association with OCs severity, assessed by the ''Midwife protocol'' of Parnas and colleagues. The relationship between MR measurements and phenomenologic variables such as age at onset, illness duration, and exposure to antipsychotic medications was explored. The relationship between MR measurements, OCs severity, and symptom presentation was also investigated. OCs severity was significantly associated with MR measurements of ventricular enlargement (bifrontal span, Evans ratio). As the severity of OCs increased, bifrontal span and Evans ratio increased. This effect was independent of age at onset, illness duration, or even antipsychotic treatment. Interestingly, bifrontal span, Evans ratio, and OCs severity score all showed a significant positive correlation with hallucinatory symptomatology. Although confirmatory studies are needed, our findings would support the idea that environmental factors, in this case severe OCs, might partly contribute to ventricular abnormalities in schizophrenia. (orig.)

  9. 75 FR 32519 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-06-08

    ... (Compressed and Liquefied Gases), under NAICS code 325120 (Industrial Gases Manufacturing). On March 23, 2010...), under NAICS code 325120 (Industrial Gases Manufacturing). Dated: June 1, 2010. Karen Hontz, Director... Propane Gas (LPG), North American Industry Classification System (NAICS) code 325120, Product Service Code...

  10. SSC San Diego Command History Calendar Year 2007

    Science.gov (United States)

    2008-03-01

    Camargo , Sylvia Salazar, Karen Manley-Guerrero, Dina Demuth, Clay Oeholke, Gannon Graue, Dee Johnson, Erwin Mier, Hoa Nguyen. Navy Multiband Terminal...Davenport, Brian Devine, Greg Doriguzzi, Richard Felkins, John Fleming, Cheryl Francisco , Sid Graser, Eric Hillis, Craig LaMaster, Susan Manor, Joel

  11. 75 FR 33814 - Tobacco Product Constituents Subcommittee of the Tobacco Products Scientific Advisory Committee...

    Science.gov (United States)

    2010-06-15

    ...] Tobacco Product Constituents Subcommittee of the Tobacco Products Scientific Advisory Committee; Notice of... to the public. Name of Committee: Tobacco Product Constituents Subcommittee of the Tobacco Products...-8900. Contact Person: Karen Templeton-Somers, Office of Science, Center for Tobacco Products, Food and...

  12. Cryptography: It’s Not Just For Electronic Mail Anymore

    Science.gov (United States)

    1993-03-01

    David Chaum . Security without identification: Transaction systems to make big brother obsolete. Communications of the ACM, 28(10): 1030-1044, Oc- tober...Jeannette Wing, Maurice Herlihy, Stewart Clamen, David Detlefs, Karen Kietzke, Richard Lerner, and Su-Yuen Ling. The Avalon language: A tutorial

  13. Kusehaisust deodoranti, lisaks ullikesi / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2009-01-01

    Moskva 31. rahvusvahelise filmifestivalist. Auhinnatud filmidest : peauhinna Püha Jüri saajast Nikolai Dostali mängufilmist "Petja teel taevariiki", FIPRESCI poolt auhinnatud Kira Muratova filmist "Meloodia väntorelile", Karen Šahnazarovi Tšehhovi ekraniseeringust "Palat nr. 6". Lisatud peaauhindade nimekiri

  14. Дезодорант с еловым запахом / Лаури Кярк

    Index Scriptorium Estoniae

    Кярк, Лаури, 1954-

    2009-01-01

    Moskva 31. rahvusvahelise filmifestivalist. Auhinnatud filmidest : peauhinna Püha Jüri saajast Nikolai Dostali mängufilmist "Petja teel taevariiki", FIPRESCI poolt auhinnatud Kira Muratova filmist "Meloodia väntorelile", Karen Šahnazarovi Tšehhovi ekraniseeringust "Palat nr. 6". Lisatud peaauhindade nimekiri

  15. South African Journal of Education: Editorial Policies

    African Journals Online (AJOL)

    Linda Liebenberg, Dalhousie University, Canada. Joanna Madalińska-Michalak, University of Warsaw, Poland. Aleidine Moeller, University of Nebraska–Lincoln, USA. Karen Murphy, The Pennsylvania State University, USA. Salim Razı, Çanakkale Onsekiz Mart University, Turkey. Rose Ruto-Korir, Moi University, Kenya.

  16. Insecticide Exposure in Parkinsonism.

    Science.gov (United States)

    2000-01-01

    WET (Whole Effluent Toxicity) Testing, SETAC Short Course, 1999 Multivariate Statistical Analysis of Ecotoxicological Data, SETAC Short Course...Chlorpyrifos between water and an aquatic macrophyte (Elodea densa). Chemosphere. 37(8):1579-1586. Karen, DJ, DR Ownby, BS Day, RW Brown, DP Shupack, GP

  17. Veterinary Research Manpower Development for Defense

    Science.gov (United States)

    2013-09-01

    Center Karen Alroy 2008 2012 Intern/Small Animal – Friendship Hospital for Animals Sarah Carter 2008 2010 Veterinarian - MSPCA at Nevins Farm ...Mukherjee, J.: Preliminary studies for the identification of brucella melitensis in the Dominican Republic goat population. 2011 Merial-NIH National

  18. Book Review: Wildlife Conservation in Farmed Landscapes ...

    African Journals Online (AJOL)

    Book Title: Wildlife Conservation in Farmed Landscapes. Book Authors: David Lindenmayer, Damian Michael, Mason Crane, Sachiko Okada, Daniel Florance, Philip Bartion & Karen Ikin. 2016, CSIRO Publishing, Unipark Building 1 Level 1, 195 Wellington Road, Clayton, VIC 3168, Australia. 232 pages, softcover, ePDF ...

  19. Circumstantial Evidence of Possible Hot Spot Activity Outside Rhodes, Eastern Mediterranean Sea

    OpenAIRE

    Miliaresis, George

    2014-01-01

    Zouzias Dimitrios, St Seymour Karen, Miliaresis George, Vamvoukakis Costas (2008). Circumstantial Evidence of Possible Hot Spot Activity Outside Rhodes, Eastern Mediterranean Sea. 3rd International Conference on the Geology of the Tethys (8-11 January, 2008, South Valley University - Aswan). [Abstract in Program

  20. 78 FR 69861 - Privacy Act of 1974; Department of Homeland Security, Federal Emergency Management Agency...

    Science.gov (United States)

    2013-11-21

    ... Homeland Security, Washington, DC 20478. For privacy issues, please contact: Karen L. Neuman, (202) 343... DEPARTMENT OF HOMELAND SECURITY Office of the Secretary [DHS-2013-0073] Privacy Act of 1974... Defense Executive Reserve System of Records AGENCY: Department of Homeland Security, Privacy Office...

  1. Lagos Notes and Records: Editorial Policies

    African Journals Online (AJOL)

    Professor Tom Byers, University of Louisville Professor Olumuyiwa Alaba, University of Lagos Professor Karen King-Aribisala, University of Lagos Professor Samuel Ade Ojo, University of Lagos Professor Niyi Osundare, University of Lagos Professor Segun Awonusi, University of Lagos Professor Adebayo Lawal, University ...

  2. · ORIGINAL ARTICLES

    African Journals Online (AJOL)

    J"fPUMALANGA f uon Mabuza, John Govere, David Durrheim, Nicros. ~. ngomezulu, Barry Bredenkamp, Karen Bames, Brian Sharp bjectives. To assess therapeutic efficacy of sulfadoxine- yrimethamine (SP) in treatment of uncomplicated lasmodium falciparum malaria 3 years after introduction in lpumalanga, South Africa.

  3. South African Medical Journal - Vol 95, No 5 (2005)

    African Journals Online (AJOL)

    ... of sulfadoxine-pyrimethamine for Plasmodium falciparum malaria · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Aaron Mabuza, John Govere, Kobus laGrange, Nicros Mngomezulu, Elizabeth Allen, Alpheus Zitha, Frans Mbokazi, David Durrheim, Karen Barnes ...

  4. Different Kinds of Matter(s)

    DEFF Research Database (Denmark)

    Rosfort, René

    2012-01-01

    This article questions the methodological conflation at work in Karen Barad's agential realism. Barad's immense appeal is first explained against the tense background of the nature/culture antagonism in the twentieth century. Then, by using some of the penetrating observations of a seventeen...

  5. Ettevõttel lasub ühiskondlik vastutus / Karen Schmidt

    Index Scriptorium Estoniae

    Schmidt, Karen

    2011-01-01

    Terve Eesti SA algatusel Eesti ettevõtete poolt moodustatud koalitsioonist "Ettevõtted HIV vastu", kuhu kuuluvad Hill & Knowlton, Nordecon, Swedbank, TNS Emor, Coca-Cola, Johnson & Johnson, Rimi Eesti Food, DHL Estonia, Boehringer Ingelheim, Radisson BLU Hotell Tallinn ja TBWA/Guvatrak. Koalitsiooni töös osales kolm aastat ka Statoil

  6. Jaani kiriku savipead ajavad juttu Nigulistes / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2004-01-01

    Niguliste muuseum-kontserdisaalis eksponeeritavatest Tartu Jaani kiriku 14. sajandi terrakotaskulptuuridest. Eksponeeritakse ka arhitektuurseid elemente - kapiteele, konsoole, päiskive. Jaani kiriku ajaloost

  7. Kiasma-mees Perttu Rastas jagas kogemusi / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2004-01-01

    Kiasma meediakonsultandi ja kuraatori Perttu Rastase ettekanne Tartus Lutsu teatrimajas muuseumi toimimisest kunstitegemise võimalikkuseni. Teksti illustreerimiseks näidati Roi Vaara, Erkki Kurenniemi, Eija Liisa Ahtila videosid. Juttu oli ka Teemu Mäki kassitapmist kujutavast videost

  8. Mies van der Rohe preemia 2011 / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2011-01-01

    20. juunil antakse Barcelonas inglise arhitektile Sir David Chipperfieldile Berliini Neues Museumi restaureerimise eest üle 2011. aasta Mies van der Rohe arhitektuuripreemia. Nimetatud võidutöö viis suuremat konkurenti, varem preemia pälvinud hooneid ja nende autoreid. Sir David Chipperfieldist, Berliini Neues Muuseumi restaureerimisest. Loetletud preemia nominendid Eestist

  9. Sales of Karen Coffee generating social impact | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-12-18

    Dec 18, 2017 ... With this background in the export business, the Sabanan Company will aim to sell ... expanding not only their business, but also their social impact in Than Daung Gyi. ... Mobile phones, Internet, and gender in Myanmar.

  10. Who's who on the Board

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    Brief summaries of the curriculum vitae and present positions held by each member of the National Radiological Protection Board are given. The members are Sir Richard Southwood, Mr. A.M. Allen, Professor A. Barret, Professor J.H. Edwards, Professor H.J. Evans, Professor K.J. Evans, Professor P. Haggett, Professor J.R. Lee, Professor J.S. Orr, Dr. R. Owen, Professor J. Peto, Dr. D.H. Roberts and Mr. M.E. Trowbridge. (U.K.)

  11. Do safeguarding concerns deter young people’s access to condoms? Issues about integrating sexual health services online

    OpenAIRE

    Evans, Andrew B.; Evans, David T.

    2016-01-01

    Condoms have been distributed freely, and regionally across England, since the ‘Teenage Pregnancy Strategy’ (Social Inclusion Unit, 1999) which highlighted England as having one of the highest rates of unplanned teenage conceptions in Western Europe. With the aim of making more accessible contraception and sex safer resources and protecting against infections, young people can obtain free condoms through selected registration and distribution points (Evans, 2005; Hadley and Evans, 2013). In 2...

  12. Three-Dimensional Computer Graphics Brain-Mapping Project

    Science.gov (United States)

    1988-03-24

    1975-76, one of these brains was hand digitized. It was then reconstructed three dimensionally, using an Evans and Sutherland Picture System 2. This...Yakovlev Collection, we use the Evans and Sutherland Picture System 2 which we have been employing for this purpose for a dozen years. Its virtue is...careful, experimentally designed new protocol (See Figure 20). Most of these heads were imaged with Computed Tomography, thanks to Clint Stiles of Picker

  13. Herbal composition Gambigyeongsinhwan (4) from Curcuma longa, Alnus japonica, and Massa Medicata Fermentata inhibits lipid accumulation in 3T3-L1 cells and regulates obesity in Otsuka Long-Evans Tokushima Fatty rats.

    Science.gov (United States)

    Roh, Jong Sung; Lee, Hyunghee; Woo, Sangee; Yoon, Miso; Kim, Jeongjun; Park, Sun Dong; Shin, Soon Shik; Yoon, Michung

    2015-08-02

    Adipocyte lipid accumulation due to impaired fatty acid oxidation causes adipocyte hypertrophy and adipose tissue increment, leading to obesity. The aim of this study was to determine the antiobesity effects of the herbal composition Gambigyeongsinhwan (4) (GGH(4)) composed of Curcuma longa L. (Zingiberaceae), Alnus japonica (Thunb.) Steud. (Betulaceae), and the fermented traditional Korean medicine Massa Medicata Fermentata. The effects of GGH(4) and the individual components on lipid accumulation in 3T3-L1 adipocytes and body weight gain in Otsuka Long-Evans Tokushima Fatty (OLETF) rats were examined using Oil red O staining, hematoxylin and eosin staining, quantitative real-time PCR, and peroxisome proliferator-activated receptor α (PPARα) transactivation assay. GGH(4), individual components, and an active principle of Curcuma longa curcumin inhibited lipid accumulation and mRNA levels of adipocyte-specific genes (PPARγ, aP2, and C/EBPα) in 3T3-L1 adipocytes compared with control cells. Treatment with GGH(4), the individual components or curcmumin increased mRNA levels of mitochondrial (CPT-1, MCAD, and VLCAD) and peroxisomal (ACOX and thiolase) PPARα target genes. GGH(4) and the individual components also increased PPARα reporter gene expression compared with control cells. These effects were most prominent in GGH(4)-treated cells. However, the PPARα antagonist GW6471 reversed the inhibitory effects of GGH(4) on adipogenesis. An in vivo study showed that GGH(4) decreased body weight gain, adipose tissue mass, and visceral adipocyte size with increasing mRNA levels of adipose tissue PPARα target genes in OLETF rats. These results demonstrate that GGH(4) has an antiobesity effects through the inhibition of adipocyte lipid accumulation, and this process may be mediated in part through adipose PPARα activation. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  14. Health Information in Sudanese (Arabic dialect) (سودانية عربية)

    Science.gov (United States)

    ... Suicide - سودانية عربية (Sudanese (Arabic dialect)) MP3 ... Karen Chemical Dependency Taskforce of Minnesota Mood Disorders What Is Mental Distress - سودانية عربية (Sudanese (Arabic ...

  15. 75 FR 17394 - Notice of Availability of Government-Owned Inventions; Available for Licensing

    Science.gov (United States)

    2010-04-06

    ... CFR part 404. Applications will be evaluated utilizing the following criteria: (1) Ability to... Jean Miller, Edward Unsworth, William Hook, Thomas Walsh, Karen Gray, and Charles Macri; 12/634,119... CONTACT: Dr. Charles Schlagel, Director, Office of Technology Transfer, Naval Medical Research Center, 503...

  16. Content Analysis in Systems Engineering Acquisition Activities

    Science.gov (United States)

    2016-04-30

    Acquisition Activities Karen Holness, Assistant Professor, NPS Update on the Department of the Navy Systems Engineering Career Competency Model Clifford...systems engineering toolkit . Having a common analysis tool that is easy to use would support the feedback of observed system performance trends from the

  17. Mefloquine prophylaxis prevents malaria during pregnancy: a double-blind, placebo-controlled study

    NARCIS (Netherlands)

    Nosten, F.; ter Kuile, F.; Maelankiri, L.; Chongsuphajaisiddhi, T.; Nopdonrattakoon, L.; Tangkitchot, S.; Boudreau, E.; Bunnag, D.; White, N. J.

    1994-01-01

    A double-blind, placebo-controlled study of mefloquine antimalarial prophylaxis in pregnancy (> 20 weeks of gestation) was conducted in 339 Karen women living in an area of multidrug-resistant malaria transmission on the Thai-Burmese border. Mefloquine gave > or = 86% (95% confidence interval [CI],

  18. 77 FR 66935 - Telephone Consumer Protection Act of 1991

    Science.gov (United States)

    2012-11-08

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 64 [CG Docket No. 02-278; FCC 12-21] Telephone Consumer Protection Act of 1991 AGENCY: Federal Communications Commission. ACTION: Final rule; correction...: Karen Johnson, Consumer and Governmental Affairs Bureau, Consumer Policy Division, at (202) 418- 7706 or...

  19. 75 FR 57941 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2010-09-23

    ... created to reduce emissions of nitrogen oxides (NO X ) from power plants and other large combustion..., Air and Radiation Docket and Information Center, Mailcode 28221T, 1200 Pennsylvania Ave., NW... FURTHER INFORMATION CONTACT: Karen VanSickle, Clean Air Markets Division, Office of Air and Radiation...

  20. Critical Naturalism : A Quantum Mechanical Ethics

    NARCIS (Netherlands)

    Dolphijn, R.

    2016-01-01

    Rereading Derrida, both Donna Haraway and Karen Barad are in search for an ethics that is not based on critique but that offers an affirmative alternative to the dualist construction of naturalism today. Whereas Haraway practices this ethics mainly by reading contemporary biology into the

  1. 75 FR 1614 - Submission for OMB Review-2010 Election Administration and Voting Survey; Comment Request

    Science.gov (United States)

    2010-01-12

    ... ballots cast; voter registration; overseas and military voting; Election Day activities; voting technology... FURTHER INFORMATION CONTACT: Ms. Karen Lynn-Dyson or Ms. Shelly Anderson at (202) 566-3100. SUPPLEMENTARY... transmitted, returned and submitted for counting (cast), and counted; (b) Total number of UOCAVA absentee...

  2. Livet i skolen - skolen i livet

    DEFF Research Database (Denmark)

    Rasmussen, Lisa Rosén

    og sanset skolehverdag. Med poststrukturalistiske begreber om tidslighed og samtidighed diskuteres, hvordan fortiden forstyrrer og intensiveres i nutiden. I analyser af erindringernes både sproglige, materielle og affektive dimensioner trækkes på teorier af bl.a. Judith Butler, Karen Barad, Eelco...

  3. CLONING, EXPRESSION, AND CHARACTERIZATION OF RAT S-ADENOSYL-L-METHIONINE: ARSENIC (III) METHYLTRANSFERASE (CYT19)

    Science.gov (United States)

    CLONING, EXPRESSION, AND CHARACTERIZATION OF RAT S-ADENOSYL-L-METHIONINE: ARSENIC(III) METHYLTRANSFERASE (cyt19)Stephen B. Waters1 , Felicia Walton1 , Miroslav Styblo1 , Karen Herbin-Davis2, and David J. Thomas2 1 School of Medicine, University of North Carolina at Chape...

  4. 77 FR 71171 - Proposed Collection; Comment Request

    Science.gov (United States)

    2012-11-29

    ... their job, level of training, system response time when entering or accessing the information, and... information collection on respondents, including through the use of automated collection techniques or other... Division, ATTN: Karen Saddoris, CDFM-A, Project Officer, 5202 Leesburg Pike, Suite 1100, Falls Church, VA...

  5. Editorial | Webster | South African Medical Journal

    African Journals Online (AJOL)

    Jacqui Webster, Christelle Crickmore, Karen Charlton, Krisela Steyn, Edelweiss Wentzel-Viljoen, Pamela Naidoo. Abstract. South Africa's salt reduction strategy: Are we on track, and what lies ahead? Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  6. South African Medical Journal - Vol 105, No 9 (2015)

    African Journals Online (AJOL)

    National Health Insurance in South Africa: Relevance of a national priority-setting agency · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Karen J Hofman, Shelley McGee, Kalipso Chalkidou, Sripen Tantivess, Anthony J Culyer, 739-740.

  7. Educators' experiences of their relationships with adolescents ...

    African Journals Online (AJOL)

    Educators' experiences of their relationships with adolescents involved in drug use. Karen Lynn Walton, J Avenant, I van Schalkwyk. Abstract. Substance use amongst learners in South Africa has become a significant problem, with relationships between educators and learners being seriously challenged. Educators are ...

  8. The effect of a dietary leucine excess on the immunoresponsiveness ...

    African Journals Online (AJOL)

    Karen J. Tinker and A.M. Gous. Departments of Biochemistry, and Animal Science and Poultry Science, University of Natal, Pietermaritzburg. The effect of a dietary leucine imbalance on chickens was investigated. The two criteria considered were growth and antibody production following immunization with sheep red.

  9. Lack of visible post-pollination effects in pollen grains of two Dendrobium cultivars: relationship with pollinia ACC, pollen germination, and pollen tube growth

    NARCIS (Netherlands)

    Luangsuwalai, K.; Ketsa, S.; Wisutiamonkul, A.; Doorn, van W.G.

    2008-01-01

    Dendrobium flowers, pollinated with pollinia from individuals of the same cultivar or other cultivars, usually show rapid post-pollination effects such as. oral epinasty, a change in flower colour and early perianth senescence. However, pollination with the pollinia of cv. Karen or cv. Kenny flowers

  10. 77 FR 28250 - Entity List Additions; Corrections

    Science.gov (United States)

    2012-05-14

    ...: Karen Nies-Vogel, Chair, End-User Review Committee, Office of the Assistant Secretary, Export... impacts, and equity). Executive Order 13563 emphasizes the importance of quantifying both costs and... hour estimate of 43.8 minutes for a manual or electronic submission. Total burden hours associated with...

  11. Grand Conversations across Texts

    Science.gov (United States)

    Crafton, Linda K., Ed.; Johnson, Nancy J., Ed.

    2008-01-01

    This issue of "School Talk" brings together the ideas of purposefulness and intertextuality together in a teaching practice called intentional intertextual inquiry. "Making Inquiry Intentional and Intertextual" (Karen Smith, Sarah Diaz, and Silvia Edgerton) discusses the framework that combines inquiry-based learning and intertextuality within…

  12. Cognitive success: instrumental justifications of normative systems of reasoning

    OpenAIRE

    Schurz, Gerhard

    2014-01-01

    In the first part of the paper (sec. 1–4), I argue that Elqayam and Evan's (2011) distinction between normative and instrumental conceptions of cognitive rationality corresponds to deontological vs. teleological accounts in meta-ethics. I suggest that Elqayam and Evans' distinction be replaced by the distinction between a-priori intuition-based vs. a-posteriori success-based accounts of cognitive rationality. The value of cognitive success lies in its instrumental rationality for almost-all p...

  13. Virgil re-purposed in the Old French «Roman d’Eneas»

    Directory of Open Access Journals (Sweden)

    Raymond Cormier

    2015-07-01

    Full Text Available In these pages, I deal with three “sticky bits” in the twelfth-century Roman d’Eneas (vv. 483-496, 534-539, and 9792-9814. These are vernacular “marvels” that have stumped concerned philologists for at least one hundred years (beginning with Edmond Faral, 1913. The first segment deals with the crocodiles found in the waters of “Libya” (i.e., Dido’s Carthage; mysteriously, they have no bowels. Next, the Capitol building in Carthage possesses special acoustics, we are told, that make distant whispers audible. Finally, Pallas’ baldric (ripped off by Turnus once he slays the youth is changed by the anonymous Old French poet to a finger ring. I attempt to offer suggested explanations for the three non-Virgilian embellishments. In questo contributo mi occupo di tre “divagazioni” che l’autore del Roman d’Eneas compie rispetto alla fonte latina (vv. 483-496, 534- 539 e 9792-9814, tre elementi del “meraviglioso” che hanno disorientato, per un centinaio d’anni (a partire da Edmond Faral, nel 1913 i filologi che se ne sono occupati. Il primo segmento tratta dei coccodrilli trovati nelle acque della “Libia” (ovvero, la Cartagine di Didone: misteriosamente, essi sono privi di viscere. Nel segmento successivo è descritto il Campidoglio di Cartagine, la cui speciale acustica consente – cosí ci dice l’autore – di ascoltare i sospiri anche a distanza. Infine, il bàlteo di Pallante (sottratto da Turno nel momento in cui egli uccide il giovane è sostituito dall’anonimo poeta antico-francese con un anello. Per ciascuno di questi abbellimenti non virgiliani, tento di offrire una spiegazione convincente. 

  14. Sisearhitektid Väino Tamm ja Vello Asi. Näitusekataloog = Interior architects Väino Tamm and Vello Asi. Exhibition catalogue

    Index Scriptorium Estoniae

    2008-01-01

    Näitusekataloogi "Tamm ja Asi" autor ja koostaja Karen Jagodin ning kujundaja Tiit Jürna pälvisid Eesti Sisearhitektide Liidu 2007. a. publitsistika preemia. Enamik raamatus publitseeritud fotodest pärineb fotograaf Rein Vainküla kogust. K. Jagodinist ja T. Jürnast, nende fotod

  15. A NOVEL S-ADENOSYL-L-METHIONINE: ARSENIC (III) METHYLTRANSFERASE FROM RAT LIVER CYTOSOL

    Science.gov (United States)

    A Novel S-Adenosyl-L-methionine: Arsenic(III) Methyltransferase from Rat Liver CytosolShan Lin, Qing Shi, F. Brent Nix, Miroslav Styblo, Melinda A. Beck, Karen M. Herbin-Davis, Larry L. Hall, Josef B. Simeonsson, and David J. Thomas S-adenosyl-L-methionine (AdoMet): ar...

  16. Nothingness and the Forgotten

    DEFF Research Database (Denmark)

    Jensen, Tine

    2016-01-01

    This chapter takes an onset in forgetting and applies Karen Barad’s agential realism to the phenomenon. The question here is neither about retrieval problems, as forgetting is coined in cognitive science, nor is it about psychoanalytical concepts of repression. Rather, this chapter conducts a tho...

  17. 77 FR 56541 - Establishment of the Inwood Valley Viticultural Area

    Science.gov (United States)

    2012-09-13

    ... Decision. SUMMARY: The Alcohol and Tobacco Tax and Trade Bureau (TTB) establishes the 28,441-acre ``Inwood... may purchase. DATES: Effective Date: October 15, 2012. FOR FURTHER INFORMATION CONTACT: Karen A... consumers and helps consumers to identify wines they may purchase. Establishment of a viticultural area is...

  18. An Evaluation of Grades 9 and 10 Mathematics Textbooks Vis-À-Vis ...

    African Journals Online (AJOL)

    An Evaluation of Grades 9 and 10 Mathematics Textbooks Vis-À-Vis Fostering Problem Solving Skills. ... Document analysis was carried out on the two textbooks using Mathematics Material Analysis Instrument (MMAI) developed by Karen (1997). Interview was held with two experts from Institute of Curriculum Development ...

  19. [Review of: K.-S. Taussig Ordinary genomes: science, citizenship, and genetic identities

    NARCIS (Netherlands)

    Kato, M.

    2010-01-01

    Ordinary Genomes is an ethnography of clinical genetics practice in the Netherlands, written by US anthropologist Karen-Sue Taussig. By looking at the case of the Netherlands, this book aims to illuminate the way specific scientific knowledge - in this case genomics - which is generally presumed to

  20. "A Clash of Two Worlds"; Disjuncture between the Norms and Values Held by Educational Practitioners and Parents of Children with Behavioural, Emotional and Social Difficulties

    Science.gov (United States)

    Broomhead, Karen

    2014-01-01

    This article, by Karen Broomhead of Liverpool John Moores University, discusses an exploration of the clashing norms, values and expectations of parenting behaviours between parents of children with behavioural, emotional and social difficulties (BESD) and practitioners. Semi-structured interviews with 15 education professionals, employed in both…

  1. Tshto smotret? Spetsvõpusk : Rossijskoje kino

    Index Scriptorium Estoniae

    2007-01-01

    Vene filmide eri : DVD-l anti välja Karen Oganesjani debüütmängufilm "Ma jään" ("Ja ostajus"), Oleg Rjaskovi "Mitme isanda teener" ("Sluga gossudarev"), Ruslan Baltseri "Pöörased päevad" ("Derzkije dni") ja "Rahuldamatud" ("Nenassõtnõje")

  2. Overcoming Language and Literacy Barriers: Using Student Response System Technology to Collect Quality Program Evaluation Data from Immigrant Participants

    Science.gov (United States)

    Walker, Susan K.; Mao, Dung

    2016-01-01

    Student response system technology was employed for parenting education program evaluation data collection with Karen adults. The technology, with translation and use of an interpreter, provided an efficient and secure method that respected oral language and collective learning preferences and accommodated literacy needs. The method was popular…

  3. Electrochemical Impedance Spectrometer with an Environmental Chamber for Rapid Screening of New Precise Copolymers

    Science.gov (United States)

    2017-10-07

    12-Oct-2017 Publication Identifier: First Page #: Volume: Date Submitted: 10/7/17 12:00AM Authors: Eric J. Bailey, Philip J. Griffin, Vera ...Stevens, Manuel Marechal, Demi E . Moed, Hakima Mendil-Jakani, Patrice Rannou, Kenneth B. Wagener, and Karen I. Winey Distribution Statement: 1-Approved

  4. African Journal of AIDS Research - Vol 12, No 3 (2013)

    African Journals Online (AJOL)

    Cost-effectiveness analysis of infant feeding strategies to prevent mother-to-child transmission of HIV in South Africa · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Mandy Maredza, Melanie Y Bertram, Haroon Saloojee, Matthew F Chersich, Stephen M Tollman, Karen J Hofman.

  5. Plasmodium falciparum malaria

    African Journals Online (AJOL)

    Durrheim, Karen Barnes. Objectives. To assess the therapeutic efficacy of sulfadoxine- pyrimethamine (SP) after 5 years of use as first-line treatment of uncomplicated Plasmodium falciparum malaria, and thus guide the selection of artemisinin-based combination therapy in Mpumalanga, South Africa. Design. An open-label ...

  6. South African Medical Journal - Vol 91, No 11 (2001)

    African Journals Online (AJOL)

    ... in uncomplicated Plasmodium falciparum malaria 3 years after introduction in Mpumalanga · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Aaron Mabuza, John M. Govere, David N. Durrheim, Barry L.F. Bredenkamp, Brian L. Sharp, Karen Barnes, 975-978 ...

  7. vaginal histological changes of the baboon

    African Journals Online (AJOL)

    2009-04-04

    Apr 4, 2009 ... be studied in humans for ethical reasons. Objective: To determine the histological changes in baboon vagina associated with cyclic variations during normal menstrual cycle. Setting: The experiments were carried out at Institute of Primate Research (IPR),. Karen, Nairobi, Kenya. Subjects: Nine adult healthy ...

  8. Ethiopian Journal of Health Development - Vol 17, No 1 (2003)

    African Journals Online (AJOL)

    Appropriate tools and methods for tropical microepidemiology: a case-study of malaria clustering in Ethiopia · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Tedros A Ghebreyesus, Peter Byass, Karen H Witten, Asfaw Getachew, Mitiku Haile, Mekonnen Yohannes, ...

  9. Outbreak of a New Strain of Flu at a Fair

    Centers for Disease Control (CDC) Podcasts

    2013-02-28

    Dr. Karen Wong, an EIS officer with the Centers for Disease Control and Prevention, discusses her study about flu outbreaks at agricultural fairs.  Created: 2/28/2013 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 3/4/2013.

  10. Interactive computer graphics for bio-stereochemical modelling

    Indian Academy of Sciences (India)

    Proc, Indian Acad. Sci., Vol. 87 A (Chem. Sci.), No. 4, April 1978, pp. 95-113, (e) printed in India. Interactive computer graphics for bio-stereochemical modelling. ROBERT REIN, SHLOMONIR, KAREN HAYDOCK and. ROBERTD MACELROY. Department of Experimental Pathology, Roswell Park Memorial Institute,. 666 Elm ...

  11. O Pecado da Carne: neomaterialismo e a (redescoberta do corpo

    Directory of Open Access Journals (Sweden)

    Caynnã de Camargo Santos

    2017-06-01

    Full Text Available O presente artigo objetiva discutir alguns fundamentos conceituais do emergente paradigma neomaterialista no contexto dos debates sobre relações de gênero e diferenças sexuais. Persigo tal objetivo mediante uma atenta leitura das principais formulações da teórica feminista norte -americana Karen Barad, uma das mais destacadas vozes vinculadas à «virada material» em curso na teoria e na prática feminista. Debruço -me, nomeadamente, sobre aspectos basilares do «realismo agencial» de Barad, que sustenta sua proposta de uma «teoria performativa pós -humanista». Em um segundo momento do trabalho, busco apresentar em linhas gerais alguns espaços de tensão entre as propostas de Karen Barad e Judith Butler, evidenciando assim as diferenças de perspectiva entre as abordagens do corpo sexuado por teóricas/os queer e neomaterialistas.

  12. Ombuds’ corner: Compromise or “win-win” solution?

    CERN Multimedia

    Vincent Vuillemin

    2011-01-01

    A managerial position in a large project led by CERN became available. Karen* and Walt*, both members of this collaboration and part of the same CERN unit, started to compete for this unique position, as they both felt that they were the most qualified.   Karen benefited from seniority and had developed excellent experience in management, which lead to her strongly believing that the post should be hers. Walt, although much younger and on a limited-duration contract, also applied for the position. He considered that his technical expertise, recognized as essential inside the project, would fully compensate for his lack of managerial skills. In addition, he strongly believed that such a project should be led by a young scientifically pro-active, inventive and person. They entered into a conflict and asked the Ombuds to help them resolve their interpersonal working difficulties, which were becoming unbearable. Through the mediation process, the...

  13. El caso de la Dama de Elche: más que una divergencia

    Directory of Open Access Journals (Sweden)

    Olmos, Ricardo

    1996-12-01

    Full Text Available A recent review of Karen D. Vitelli appeared in American Journal of Archaeology (1995, 775 on John F. Moffitt's Art Forgery. The case of the Lady of Elche, is the reason that make us to write this paper. It is discussed here both method and content of a book showing a scientific intention but inaceptable conclusions. The Lady of Elche deserves a better approach from the light of the new Iberian archaeological research.Una reciente recensión de Karen D. Vitelli aparecida en American Journal of Archaeology (1995, 775 sobre el libro de John F. Moffitt Art Forgery. The case of the Lady of Elche, es el motivo de nuestro escrito. Se discute aquí el método y contenido de un libro con intención científica y conclusiones inaceptables. La Dama de Elche merece una mejor aproximación desde la luz de la nueva investigación de la arqueología ibérica.

  14. Cardiovascular Ultrasound of Neonatal Long Evans Rats ...

    Science.gov (United States)

    This abstract describes the use of a relatively new technology, cardiovascular ultrasound (echocardiography) for evaluating developmental toxicity affecting heart development. The abstract describes the effects of two known cardiac teratogens, trichloroacetic acid and dimethadione, and their effects as determined by echocardiography. This abstract describes the use and development of a relatively new technology, cardiovascular ultrasound (echocardiography) for evaluating developmental toxicity affecting heart development.

  15. Meie igapäevane paanika / Ott Karulin

    Index Scriptorium Estoniae

    Karulin, Ott, 1980-

    2007-01-01

    Kahest Vanemuise teatri lavastusest Tartus - Saksa Kultuuri Instituudis etendunud Ingvar Ambjornseni-Axel Hellsteniuse "Elling" Ain Mäeotsa lavastuses ja Laura Cunninghami "Beautiful Bodies" Vanemuises, lavastaja Jüri Lumiste

  16. Kwashiorkor and Intellectual Development | Evans | South African ...

    African Journals Online (AJOL)

    Forty Cape Coloured children who had been hospitalized for kwashiorkor in infancy were compared with their siblings on an intelligence test battery at the 10th ... groups found by previous investigators may be accounted for by the independent operation of non-nutritive variables in the social and emotional environment.

  17. OrthoImagery Submission for Evans County, GA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — NAIP imagery is available for distribution within 60 days of the end of a flying season and is intended to provide current information of agricultural conditions in...

  18. Science in the Performance Stratum : Hunting for Higgs and Nature as Performance

    NARCIS (Netherlands)

    Bleeker, Maaike; van der Tuin, Iris

    2014-01-01

    Recent traditions such as posthumanism and new materialism propose that non- humans and matter are active participants in processes of signification, so that humans do not give meaning to matter, but matter and meaning co-constitute each other. Notably, Karen Barad’s plea for ‘the study of practices

  19. 78 FR 63017 - Exhaust Emissions Standards for New Aircraft Gas Turbine Engines and Identification Plate for...

    Science.gov (United States)

    2013-10-23

    [email protected] . For legal questions concerning this action contact Karen Petronis, International Law... adopting the gas turbine engine test procedures of the International Civil Aviation Organization (ICAO... regulation did not apply. The word ``exemption'' has a specific legal meaning. In 14 CFR Part 11 the FAA uses...

  20. Collaborative Leadership as a Catalyst for Change

    Science.gov (United States)

    Davenport, Allan; Mattson, Kristen

    2018-01-01

    In the spring of 2015, Dr. Karen Sullivan, superintendent of Indian Prairie School District 204 in Aurora, Illinois, signed the Alliance for Excellent Education's Future Ready Pledge, "making a firm commitment to implementing meaningful changes toward a digital learning transition that supports teachers, and addresses the district's vision…

  1. Measuring Music Education: A Philosophical Investigation of the Model Cornerstone Assessments

    Science.gov (United States)

    Richerme, Lauren Kapalka

    2016-01-01

    Despite substantial attention to measurement and assessment in contemporary education and music education policy and practice, the process of measurement has gone largely undiscussed in music education philosophy. Using the work of physicist and philosopher Karen Barad, in this philosophical inquiry, I investigated the nature of measurement in…

  2. Malaria Genome Sequencing Project

    Science.gov (United States)

    2004-01-01

    UTTERBACK, TERESA RIGGS, FLORENCE VAN AKEN, SUSAN RIZZO, MICHAEL VISWANATHAN, LAKSHMI ROMERO , CALUDIA DEVI ROONEY, TIMOTHY VON ARX, ANNA RUCH, KAREN...Clark*, R. Clark*, C. Corton *, well with the predictions from the optical map. Chromosome 13 is A. Cronin*, R. Davies*, P. Davis*, P. Dear§, F. Dearden

  3. 77 FR 16674 - Establishment of the Wisconsin Ledge Viticultural Area

    Science.gov (United States)

    2012-03-22

    ... Decision. SUMMARY: The Alcohol and Tobacco Tax and Trade Bureau establishes the approximately 3,800 square... wines they may purchase. DATES: Effective Date: April 23, 2012. FOR FURTHER INFORMATION CONTACT: Karen A... consumers and helps consumers to identify wines they may purchase. Establishment of a viticultural area is...

  4. Forum: Cultural Identity and (Dis)Continuities of Children of Immigrant Communities

    Science.gov (United States)

    Obsiye, Mohamed; Cook, Rachel

    2016-01-01

    Susan Harper's study centres on "funds of knowledge" as a pedagogical resource for the development of a science curriculum, drawing on Karen refugee parents' cultural knowledge and identity. She argues that engagement in this process helps the parent generation of this community to "rebuild their cultural resilience" and cope…

  5. 77 FR 21077 - Codex Alimentarius Commission: Meeting of the Codex Committee on Food Labeling

    Science.gov (United States)

    2012-04-09

    ... guidelines; (c) studying specific labeling problems assigned to it by Codex; and (d) studying problems... Production, Processing, Labeling and Marketing of Organically Produced Foods. (a) Inclusion of Ethylene for... on: April 3, 2012. Karen Stuck, U.S. Manager for Codex Alimentarius. [FR Doc. 2012-8505 Filed 4-6-12...

  6. Scientific Results of Yoga for Health and Well-Being

    Medline Plus

    Full Text Available ... Southern California) An overview of a rigorously designed study that shows yoga may benefit people with chronic low-back pain, a common and difficult-to-treat problem. (Karen Sherman, Ph.D., M.P.H., Group Health Research Institute) Valuable “dos and don’ts” for consumers ...

  7. Saving and Accessing the Old IR Literature

    NARCIS (Netherlands)

    Harman, D.; Hiemstra, Djoerd

    2008-01-01

    This short paper describes the beginnings of a project to digitize some of the older literature in the information retrieval field. So far 14 of the older reports, such as the Cranfield reports and ISR reports have been scanned, along with Karen Sparck Jones's Information Retrieval Experiment book.

  8. Et håndtryk

    DEFF Research Database (Denmark)

    2010-01-01

    Hør Karen Westphal Eriksen fortælle om udvalgte værker og temaer fra udstillingen "Et håndtryk". Udstillingen omhandler dansk-fransk avantgardekunst og er et samarbejde mellem Fyns Kunstmuseum og Statens Museum for Kunst. Udstillingen kan ses på Fyns Kunstmuseum frem til februar 2011...

  9. STATUS, CHALLENGES AND MARKETING OPPORTUNITIES FOR ...

    African Journals Online (AJOL)

    kitonyo

    the Ethiopian rift valley especially in Oromia and north of Lake Ziway regions. Since ... In 2001, the Eastern and Central Africa Bean Research Network ... KEPHIS and Horticultural Crops Development Authority (HCDA), and supermarket ... markets of Westlands, Karen and Ngong and the Nairobi city centre stock a variety of.

  10. 78 FR 77151 - Notice of Senior Executive Service Performance Review Board Appointments

    Science.gov (United States)

    2013-12-20

    ... J. Wenk, Daniel N. Werkheiser, William H. White, John Ethan Whitesell, Stephen E. Whittington.... Applegate, James D. R. Arroyo, Bryan Atkinson, Karen J. Austin, Stanley J. Awn I, Muhammad H. Bales, Jerad D.... Davis, Mark H. Dean, Francis J. Deerinwater, Daniel J. Delaplaine, L. Bruce Demulder, Mark L. Dickinson...

  11. 76 FR 58277 - Performance Review Board Members

    Science.gov (United States)

    2011-09-20

    .... Cantrell, Patrick H. Conway, Kathleen M. Crosby, John Czajkowski, Cheryl R. Dammons, Michelle S. Davis..., William B. Schultz, Neil Shapiro, Jeremy B. Sharp, George H. Sheldon, Steven D. Silverman, Rebecca T... E. Tyler Jr., Stephen J. Veneruso, Karen V. Walker Bryce, Luis A. Wilmot, Holly J. Wong, Robert K...

  12. EDITORIAL NOTE

    African Journals Online (AJOL)

    Mugumbate

    I would like to take this opportunity to thank the. Editorial Board and reviewers for their support. I would want to single out Professor Karen Lyons (PhD, CQSW, Emeritus Professor,. International Social Work, Faculty of Social Sciences and Humanities,. London Metropolitan University, UK) for immense contribution during.

  13. Golden Hadron awards for the LHC's top suppliers.

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    The following firms have been selected to receive a GOLDEN HADRON AWARD 2003, in recognition of their outstanding achievement: JDL TECHNOLOGIES, Belgium "in producing automatic cable inspection systems", FURUKAWA ELECTRIC COMPANY, Japan "in producing high quality superconducting cable", IHI Corporation, Japan, and LINDE KRYOTECHNIK, Switzerland "in producing novel 1.8 K refrigeration units based on advanced cold compressor technology" for the Large Hadron Collider.Photos 01, 02: Recipients of the 2003 Golden Hadron awards at the presentation ceremony on 16 May.Photo 03: LHC project leader Lyn Evans updates the award recipients on work for CERN's new accelerator.Photo 04: René Joannes of JDL Technologies (left) receives a Golden Hadron award from LHC project leader Lyn Evans.Shinichiro Meguro, managing director of Furukawa Electric Company, receives a Golden Hadron award from LHC project leader Lyn Evans.Photo 06: Kirkor Kurtcuoglu of Linde Kryotechnik (left) and Motoki Yoshinaga, associate director of IHI...

  14. Gold awards for CERN's top suppliers!

    CERN Multimedia

    2003-01-01

    CERN's awards to the LHC project's best suppliers are now into their second year. Three companies received 'Golden Hadrons' for 2003. The Golden Hadron awards were presented to the delighted representatives of the winning firms by LHC Project Leader Lyn Evans on Friday 16 May. Only three out of the LHC's four hundred suppliers were lucky enough to receive a gold award. The consortium IHI (Japan)-Linde Kryotechnik (Switzerland), the Belgian company JDL Technologies and the Japanese firm Furukawa Electric Company were rewarded not only for their technical and financial achievements but also for their compliance with contractual deadlines. The 2003 Golden Hadron winners with Lyn Evans. From left to right: Armin Senn, Thomas Voigt, Kirkor Kurtcuoglu of LINDE KRYOTECHNIK ; Tadaaki Honda, Project Leader and Motoki Yoshinaga, Associate Director of IHI Corporation ; Lyn Evans, LHC Project Leader; Shinichiro Meguro, Managing Director of FURUKAWA ELECTRIC COMPANY ; Nobuyoshi Saji, Consulting Engineer of IHI Corporatio...

  15. Craniofacial form is altered by chronic adult exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD in Han/Wistar and Long–Evans rats with different aryl hydrocarbon receptor (AhR structures

    Directory of Open Access Journals (Sweden)

    Sabrina B. Sholts

    2015-01-01

    Full Text Available Mammalian bone has shown a variety of responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD exposure in experimental and wildlife studies. Although many responses have been well characterized in the postcranial skeleton, dioxin-induced effects on the cranium are largely unknown. In this study, we investigated the effects of chronic adult exposure to TCDD on cranial size and shape in dioxin-resistant Han/Wistar (H/W and dioxin-sensitive Long–Evans (L–E rat strains. Three-dimensional landmark configurations for the face, vault, and base of the cranium were recorded and analyzed using geometric morphometrics (GM and dose–response modeling. The strongest effects were shown by L–E and H/W rats with daily exposures of 100 and 1000 ng TCDD/kg bw/day, respectively, resulting in significant reductions in centroid size (CS in all three cranial modules for both strains except for the vault in H/W rats. Consistent with previous evidence of intraspecific variation in TCDD resistance, the benchmark doses (CEDs for cranial size reduction in L–E rats were roughly 10-fold lower than those for H/W rats. For both strains, the face showed the greatest size reduction from the highest doses of TCDD (i.e., 3.6 and 6.3% decreases in H/W and L–E rats, respectively, most likely related to dose-dependent reductions in limb bone size and body weight gain. However, intrinsic morphological differences between strains were also observed: although the control groups of H/W and L–E rats had vaults and bases of comparable size, the face was 6.4% larger in L–E rats. Thus, although H/W rats possess an altered aryl hydrocarbon receptor (AhR that appears to mediate and provides some resistance to TCDD exposure, their smaller reductions in facial size may also relate to strain-specific patterns of cranial development and growth. Future research will be aimed at understanding how ontogenetic factors may modulate toxic effects of prenatal and lactational exposure on

  16. Preparing the Next Generation of Educators for Democracy

    Science.gov (United States)

    Embry-Jenlink, Karen

    2018-01-01

    In the keynote address of the 42nd annual meeting of the Southeastern Regional Educators Association (SRATE), ATE President Karen Embry-Jenlink examines the critical role of teacher educators in preparing the next generation of citizens and leaders to sustain democracy. Drawing from historic and current events and personal experience,…

  17. The Spirit of Lucifer

    DEFF Research Database (Denmark)

    Skriver, Svend

    2015-01-01

    Highlighting so far unnoted and posthumously published material, the article aims to view the literary myth and works of Karen Blixen from a new perspective. The article contains a reading of the early short story fragment ‘The Story of Sebastian di Sandoval who gave his Soul to the Devil'...

  18. Catalogue 2.0 the future of the library catalogue

    CERN Document Server

    Chambers, Sally

    2014-01-01

    Brings together some of the foremost international cataloguing practitioners and thought leaders, including Lorcan Dempsey, Emmanuelle Bermès, Marshall Breeding and Karen Calhoun, to provide an overview of the current state of the art of the library catalogue and look ahead to see what the library catalogue might become.

  19. Making Biology Relevant to Undergraduates

    Science.gov (United States)

    Musante, Susan

    2012-01-01

    This article features Science Education for New Civic Engagements and Responsibilities (SENCER; www.sencer.net) Summer Institute. The SENCER program, which began formally in 2001, was the vision of David Burns; Karen Oates, currently Peterson Family Dean of Arts and Sciences at Worcester Polytechnic Institute; and Ric Wiebl, currently director of…

  20. 78 FR 44179 - Sunshine Act Meetings

    Science.gov (United States)

    2013-07-23

    ...: Commissioners' Conference Room, 11555 Rockville Pike, Rockville, Maryland. STATUS: Public and Closed. Week of... Hayes, 301-415-8375). This meeting will be webcast live at the Web address-- http://www.nrc.gov . 3:00 p.m. Briefing on NRC International Activities (Closed--Ex. 1 & 9) (Contact: Karen Henderson, 301-415...