WorldWideScience

Sample records for k-2 3-5 6-8

  1. Characterizing K2 Exoplanets with NIR Transit Photometry from the 3.5m WIYN Telescope

    Science.gov (United States)

    Colon, Knicole D.; Barclay, Thomas; Thompson, Susan E.; Coughlin, Jeffrey; Barentsen, Geert; Quintana, Elisa V.

    2017-01-01

    The NASA K2 mission has discovered over 400 transiting exoplanets as of October 2016 and continues to produce new discoveries on a regular basis. Expected to launch in late 2017, the Transiting Exoplanet Survey Satellite (TESS) will continue the era of exoplanet discovery by performing an all-sky search for transiting exoplanets. Given the ever increasing number of known exoplanets, it is critical that we optimize follow-up observations now in order to characterize the many interesting systems discovered by these missions. For example, K2 is finding (and TESS will find even more) small, super-Earth-size planets around cool, nearby stars. I will present results from our program for near-infrared (NIR) transit photometry of K2 exoplanet candidates conducted using the 3.5m WIYN telescope at Kitt Peak National Observatory. NIR transit photometry with the high spatial resolution WHIRC imager installed on the WIYN telescope allows us to confirm the transit host, to verify that the transit is achromatic, and to constrain the planet radius by minimizing effects of stellar limb darkening. Furthermore, the high-precision and high-cadence photometry from WIYN+WHIRC allows us to track and constrain the transit ephemeris, which is crucial for future follow-up efforts with other facilities like the upcoming James Webb Space Telescope (JWST). Ultimately, this program will vet K2 exoplanet candidates and identify prime targets for detailed characterization with JWST. This program complements K2 follow-up being done with the Spitzer Space Telescope and demonstrates the capabilities of a ground-based facility that can be used to characterize small planets from K2 and TESS for years to come.This work was supported by the NASA-NSF Exoplanet Observational Research (NN-EXPLORE) program.

  2. Stepwise Polychlorination of 8-Chloro-BODIPY and Regioselective Functionalization of 2,3,5,6,8-Pentachloro-BODIPY.

    Science.gov (United States)

    Zhao, Ning; Xuan, Sunting; Fronczek, Frank R; Smith, Kevin M; Vicente, M Graça H

    2015-08-21

    An effective, stepwise methodology for polychlorination of BODIPY using trichloroisocyanuric acid (TCCA) in acetic acid was developed. In this way, selectively substituted di-, tri-, tetra-, and pentachloro-BODIPYs 2-5 were prepared. The pentachloro-BODIPY is shown to undergo regioselective Pd(0)-catalyzed Stille and Suzuki coupling reactions, first at the 8-position followed by the 3,5- and then the 2,6-positions; nucleophilic substitution reactions occur first at the 8- followed by the 3,5-positions, while the 2,6 are unreactive.

  3. Synthesis and Crystal Structure of 15,16-Bis((4-nitrophenoxy)methyl)-2,3,5,6,8,9,11,12- octahydrobenzo[b][1,4,7,10,13]pentaoxacyclopentadecine

    Institute of Scientific and Technical Information of China (English)

    HAN Jian-Rong; ZHEN Xiao-Li; TIAN Xia; LIU Shou-Xin

    2012-01-01

    Double-armed crown ether 15,16-bis((4-nitrophenoxy)methyl)-2,3,5,6,8,9,11,12-octahydrobenzo[b][1,4,7,10,13] pentaoxacyclopentadecine F.W. 570.54 was synthesized by dibromomethyl benzo-15-crown-5 with 4-nitrophenol in the presence of anhydrous K2CO3, characterized by spectroscopic techniques and confirmed by X-ray crystal structure analysis. The title compound crystallizes in monoclinic, space group P21/c with a = 12.840(4), b = 9.425(3), c = 22.447(7), β = 98.128(7)° and Z = 4. The structure exhibits intermolecular hydrogen bonding of C-H···O type.

  4. Mechanochemical synthesis and crystal structure of a 1:2 co-crystal of 1,3,6,8-tetraazatricyclo[4.3.1.13,8]undecane (TATU and 4-chloro-3,5-dimethylphenol

    Directory of Open Access Journals (Sweden)

    Augusto Rivera

    2016-11-01

    Full Text Available Solvent-free treatment of 1,3,6,8-tetraazatricyclo[4.3.1.13,8]undecano (TATU with 4-chloro-3,5-dimethylphenol led to the formation of the title co-crystal, C7H14N4·2C8H9ClO. The asymmetric unit contains one aminal cage molecule and two phenol molecules linked via two O—H...N hydrogen bonds. In the aminal cage, the N–CH2–CH2–N unit is slightly distorted from a syn periplanar geometry. Aromatic π–π stacking between the benzene rings from two different neighbouring phenol molecules [centroid–centroid distance = 4.0570 (11 Å] consolidates the crystal packing.

  5. Computational studies on the crystal structure, thermodynamic properties, detonation performance, and pyrolysis mechanism of 2,4,6,8-tetranitro-1,3,5,7-tetraazacubane as a novel high energy density material.

    Science.gov (United States)

    Wang, Fang; Du, Hongchen; Zhang, Jianying; Gong, Xuedong

    2011-10-27

    Studies have suggested that octanitrocubane (ONC) is one of the most powerful non-nuclear high energy density material (HEDM) currently known. 2,4,6,8-Tetranitro-1,3,5,7-tetraazacubane (TNTAC) studied in this work may also be a novel HEDM due to its high nitrogen content and crystal density. Density functional theory and molecular mechanics methods have been employed to study the crystal structure, IR spectrum, electronic structure, thermodynamic properties, gas-phase and condensed-phase heat of formation, detonation performance, and pyrolysis mechanism of TNTAC. The TNTAC has a predicted density of about 2.12 g/cm(3), and its detonation velocity (10.42 km/s) and detonation pressure (52.82 GPa) are higher than that of ONC. The crystalline packing is P2(1)2(1)2(1), and the corresponding cell parameters are Z = 4, a = 8.87 Å, b = 8.87 Å, and c = 11.47 Å. Both the density of states of the predicted crystal and the bond dissociation energy of the molecule in gas phase show that the cage C-N bond is the trigger bond during thermolysis. The activation energy of the pyrolysis initiation reaction obtained from the B3LYP/6-311++G(2df,2p) level is 125.98 kJ/mol, which indicates that TNTAC meets the thermal stability request as an exploitable HEDM.

  6. Spectral investigation of the effect of anion on the stability of non covalent assemblies of 2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclopentadecine (benzo-15-crown-5) with sodium halides

    Science.gov (United States)

    Ghildiyal, Namrata; Pant, Geeta Joshi nee; Rawat, M. S. M.; Singh, Khushboo

    2017-01-01

    A series of complexes of 2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclopentadecine (benzo-15-crown-5) with sodium halides was synthesized in acetonitrile. The effect of anion on the stability and spectral properties of complexes of benzo-15-crown-5 with sodium halides was investigated. The synthesis of complexes of sodium fluoride and sodium chloride are reported for the first time. Chloroform was used as solvent to study the assembly in solution state by 1H and 13C NMR techniques. Single crystal diffraction studies on the easily crystallizable bromide complex confirmed 1:1 stoichiometry of the complex. IR and Raman studies provided valuable evidence for a water molecule shared between the crown encapsulated cation and the counter ion to give a solvent shared ion pair (SSIP). The fluorescence spectra of the complexes were obtained in chloroform by excitation at 270 nm to study the effect of complexation on the fluorescent properties of benzo-15-crown-5.

  7. Visualization of drug-nucleic acid interactions at atomic resolution. VI. Structure of two drug/ dinucleoside monophosphate crystalline complexes, ellipticine: 5-iodocytidylyl(3'-5')guanosine and 3,5,6,8-tetramethyl-n-methyl phenanthrolinium: 5-iodocytidylyl(3'-5')guanosine

    Energy Technology Data Exchange (ETDEWEB)

    Jain, S.C.; Bhandary, K.K.; Sobell, H.M.

    1979-01-01

    Ellipticine and 3,5,6,8-tetramethyl-N-methyl phenanthrolinium (TMP) form complexes with the dinucleoside monophosphate, 5-iodocytidylyl(3'-5')guanosine (iodoCpG). These crystals are isomorphous: ellipticine-iodoCpG crystals are monoclinic, space group P2/sub 1/, with a = 13.88 A, b = 19.11 A, c = 21.42 A, ..beta.. = 105.4; TMP-iodoCpG crystals are monoclinic, space group P2/sub 1/, with a = 13.99 A, b = 19.12 A, c = 21.31 A, ..beta.. = 104.9. Both structures have been solved to atomic resolution by Patterson and Fourier methods, and refined by full matrix least squares. The asymmetric unit in the ellipticine-iodoCpG structure contains two ellipticine molecules, two iodoCpG molecules, 16 water molecules and 2 methanol molecules, a total of 140 atoms, whereas, in the tetramethyl-N-methyl phenanthrolinium-iodoCpG complex, the asymmetric unit contains two TMP molecules, two iodoCpG molecules, 17 water molecules and 2 methanol molecules, a total of 141 atoms. In both structures, the two iodoCpG molecules are hydrogen bonded together by guanine-cytosine Watson--Crick base-pairing. Adjacent base-pairs within this paired iodoCpG structure are separated by about 6.7 A; this separation results from intercalative binding by one ellipticine (of TMP) molecule and stacking by the other ellipticine (or TMP) molecule above or below the base-pairs. Base-pairs within the paired nucleotide units are related by a twist of 10 to 12/sup 0/. The stereochemistry observed in these model drug-nucleic acid intercalative complexes is almost identical to that observed in the ethidium-iodoUpA and iodoCpG complexesdetermined previously. This stereochemistry is also very similar to that observed in the 9-amino-acridine-iodoCpG and acridine orange-iodoCpG complexes.

  8. K2SC: K2 Systematics Correction

    Science.gov (United States)

    Aigrain, Suzanne; Parviainen, Hannu; Pope, Benjamin

    2016-05-01

    K2SC (K2 Systematics Correction) models instrumental systematics and astrophysical variability in light curves from the K2 mission. It enables the user to remove both position-dependent systematics and time-dependent variability (e.g., for transit searches) or to remove systematics while preserving variability (for variability studies). K2SC automatically computes estimates of the period, amplitude and evolution timescale of the variability for periodic variables and can be run on ASCII and FITS light curve files. Written in Python, this pipeline requires NumPy, SciPy, MPI4Py, Astropy (ascl:1304.002), and George (ascl:1511.015).

  9. K2 & Solar System Science

    Science.gov (United States)

    Lissauer, Jack

    2015-01-01

    All of the fields that K2 observes are near the ecliptic plane in order to minimize the spin-up of the spacecraft in response to the effects of solar irradiation. The fields observed by K2 are thus rich in Solar System objects including planets, asteroids and trans-Neptunian objects (TNOs). K2 has already performed observations of Neptune and its large moon Triton, 68 Trojan and Hilda asteroids, 5 TNOs (including Pluto) and Comet C/2013 A1 (Siding Springs). About 10,000 main-belt asteroids that fell into the pixel masks of stars have been serendipitously observed. Observations of small bodies are especially useful for determining rotation periods. Uranus will be observed in a future campaign (C8), as will many more small Solar System bodies. The status of various K2 Solar System studies will be reviewed and placed within the context of our current knowledge of the objects being observed.

  10. k2photometry: Read, reduce and detrend K2 photometry

    DEFF Research Database (Denmark)

    Van Eylen, Vincent; Nowak, Grzegorz; Albrecht, Simon;

    2016-01-01

    k2photometry reads, reduces and detrends K2 photometry and searches for transiting planets. MAST database pixel files are used as input; the output includes raw lightcurves, detrended lightcurves and a transit search can be performed as well. Stellar variability is not typically well-preserved bu......-preserved but parameters can be tweaked to change that. The BLS algorithm used to detect periodic events is a Python implementation by Ruth Angus and Dan Foreman-Mackey (https://github.com/dfm/python-bls)....

  11. 38 CFR 6.8 - Selection, revocation and election.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Selection, revocation and election. 6.8 Section 6.8 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS UNITED STATES GOVERNMENT LIFE INSURANCE Optional Settlement § 6.8 Selection, revocation and election....

  12. K2SC: Flexible systematics correction and detrending of K2 light curves using Gaussian Process regression

    CERN Document Server

    Aigrain, Suzanne; Pope, Benjamin

    2016-01-01

    We present K2SC (K2 Systematics Correction), a Python pipeline to model instrumental systematics and astrophysical variability in light curves from the K2 mission. K2SC uses Gaussian process regression to model position-dependent systematics and time-dependent variability simultaneously, enabling the user to remove both (e.g., for transit searches) or to remove systematics while preserving variability (for variability studies). For periodic variables, K2SC automatically computes estimates of the period, amplitude and evolution timescale of the variability. We apply K2SC to publicly available K2 data from campaigns 3--5, showing that we obtain photometric precision approaching that of the original Kepler mission. We compare our results to other publicly available K2 pipelines, showing that we obtain similar or better results, on average. We use transit injection and recovery tests to evaluate the impact of K2SC on planetary transit searches in K2 PDC (Pre-search Data Conditioning) data, for planet-to-star radi...

  13. 3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydro-2-naphthoic acid (AHTN–COOH

    Directory of Open Access Journals (Sweden)

    Irene Nehls

    2010-10-01

    Full Text Available The title compound, C17H24O2, is the product of a haloform reaction of 6-acetyl-1,1,2,4,4,7-hexamethyltetraline (AHTN. The compound is a racemic mixture with a disorder in its aliphatic ring [occupany ratio 0.683 (4:0.317 (4] due to two possible half-chair forms. The carboxylic acid unit is slightly twisted out of coplanarity with the aromatic system [dihedral angle = 29.26 (6°]. In the crystal, pairs of short classical intermolecular O—H...O hydrogen bonds link pairs of molecules around a center of symmetry.

  14. CCDC 1015949: Experimental Crystal Structure Determination : 1,3,6,8-tetrakis(3,5-bis(trifluoromethyl)phenyl)pyrene

    KAUST Repository

    El-Assaad, Tarek H.

    2015-01-01

    An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

  15. K2SC: flexible systematics correction and detrending of K2 light curves using Gaussian process regression

    Science.gov (United States)

    Aigrain, S.; Parviainen, H.; Pope, B. J. S.

    2016-07-01

    We present K2SC (K2 Systematics Correction), a PYTHON pipeline to model instrumental systematics and astrophysical variability in light curves from the K2 mission. K2SC uses Gaussian Process regression to model position-dependent systematics and time-dependent variability simultaneously, enabling the user to remove both (e.g. for transit searches) or to remove systematics while preserving variability (for variability studies). For periodic variables, K2SC automatically computes estimates of the period, amplitude and evolution time-scale of the variability. We apply K2SC to publicly available K2 data from Campaigns 3-5 showing that we obtain photometric precision approaching that of the original Kepler mission. We compare our results to other publicly available K2 pipelines, showing that we obtain similar or better results, on average. We use transit injection and recovery tests to evaluate the impact of K2SC on planetary transit searches in K2 Pre-search Data Conditioning data, for planet-to-star radius ratios down to Rp/R* = 0.01 and periods up to P = 40 d, and show that K2SC significantly improves the ability to distinguish between true and false detections, particularly for small planets. K2SC can be run automatically on many light curves, or manually tailored for specific objects such as pulsating stars or large amplitude eclipsing binaries. It can be run on ASCII and FITS light-curve files, regardless of their origin. Both the code and the processed light curves are publicly available, and we provide instructions for downloading and using them. The methodology used by K2SC will be applicable to future transit search missions such as TESS and PLATO.

  16. Search for 2K(2\

    CERN Document Server

    Gavriljuk, Ju M; Kazalov, V V; Kuzminov, V V; Panasenko, S I; Ratkevich, S S; Zhantudueva, D A; Yakimenko, S P

    2011-01-01

    Results of a search for Kr-78 double K-capture at the second stage of the experiment with high-pressure copper proportional counters are presented. The method is based on comparison of spectra measured with natural and enriched krypton. The total exposure of the low background measurements is for Kr-78 152 g*yr and for Kr-nat 106 g*yr. An excess of events was observed in the analysis of Kr-78 selected data collected during 2008-2010 years. This excess could correspond to a double K-capture of Kr-78 with the half-life of T_{1/2}(2K,2\

  17. K2-97b

    DEFF Research Database (Denmark)

    Grunblatt, Samuel K.; Huber, Daniel; Gaidos, Eric J.;

    2016-01-01

    of the planet. These processes can be distinguished if the planet becomes highly irradiated only when the host star evolves onto the red giant branch. We report the discovery of K2-97b, a 1.31 +/- 0.11 R-J, 1.10 +/- 0.11 M-J planet orbiting a 4.20 +/- 0.14 R-circle dot, 1.16 +/- 0.12 M-circle dot red giant star...... with an orbital period of 8.4 days. We precisely constrained stellar and planetary parameters by combining asteroseismology, spectroscopy, and granulation noise modeling along with transit and radial velocity measurements. The uncertainty in planet radius is dominated by systematic differences in transit depth......, which we measure to be up to 30% between different light-curve reduction methods. Our calculations indicate the incident flux on this planet was 170(-60)(+140) times the incident flux on Earth, while the star was on the main sequence. Previous studies suggest that this incident flux is insufficient...

  18. Data analysis & probability drill sheets : grades 6-8

    CERN Document Server

    Forest, Chris

    2011-01-01

    For grades 6-8, our Common Core State Standards-based resource meets the data analysis & probability concepts addressed by the NCTM standards and encourages your students to review the concepts in unique ways. Each drill sheet contains warm-up and timed drill activities for the student to practice data analysis & probability concepts.

  19. The People of South Asia [Grades 6-8].

    Science.gov (United States)

    Adams, George; And Others

    A resource book for grades 6-8 contains materials to enrich a unit on South Asia. Material is divided into 13 sections. Sections 1-4 outline the rationale, goals, and objectives of the unit. Emphasis is placed on providing background for the understanding of South Asian cultural groups in the United States. Ten objectives are listed, including the…

  20. Geometry task & drill sheets : grades 6-8

    CERN Document Server

    Rosenberg, Mary

    2011-01-01

    For grades 6-8, our Common Core State Standards-based combined resource meets the geometry concepts addressed by the NCTM standards and encourages the students to review the concepts in unique ways. The task sheets introduce the mathematical concepts to the students around a central problem taken from real-life experiences, while the drill sheets provide warm-up and timed practice questions for the students to strengthen their procedural proficiency skills.

  1. 1,3,6,8-Tetranitrocarbazole (TNC) Synthesis and Optimization

    Science.gov (United States)

    2013-03-01

    Specification MIL-T-13 11 Distribution List 25 FIGURES 1 Carbazole added to sulphuric acid , heated till carbazole becomes sulfonated 1 2 Three-stage...1,3,6,8-TETRANITROCABAZOLE The TNC has traditionally been synthesized with a mixed acid system of sulphuric acid and nitric acid . The carbazole...is added to the sulphuric acid and heated until the carbazole becomes fully sulfonated (fig. 1). Then nitric acid is added to the mixture and

  2. The K2-TESS Stellar Properties Catalog

    CERN Document Server

    Stassun, Keivan G; Paegert, Martin; De Lee, Nathan; Sanchis-Ojeda, Roberto

    2014-01-01

    We introduce a catalog of stellar properties for stars observed by the Kepler follow-on mission, K2. We base the catalog on a cross-match between the K2 Campaign target lists and the current working version of the NASA TESS target catalog. The resulting K2-TESS Stellar Properties Catalog includes value-added information from the TESS Target Catalog, including stellar colors, proper motions, and an estimated luminosity class (dwarf/subgiant versus giant) for each star based on a reduced-proper-motion criterion. Also included is the Guest Observer program identification number(s) associated with each K2 target. The K2-TESS Stellar Properties Catalog is available to the community as a freely accessible data portal on the Filtergraph system at: http://filtergraph.vanderbilt.edu/tess_k2campaigns .

  3. Rank of K2 of elliptic curves

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    We prove that (i) rank(K2(E)) 1 for all elliptic curves E defined over Q with a rational torsion point of exact order N 4; (ii) rank(K2(E)) 1 for all but at most one R-isomorphism class of elliptic curves E defined over Q with a rational torsion point of exact order 3. We give some sufficient conditions for rank(K2(EZ)) 1.

  4. Rank of K2 of elliptic curves

    Institute of Scientific and Technical Information of China (English)

    JI QingZhong; QIN HouRong

    2009-01-01

    We prove that (i) rank(K2(E))≥1 for all elliptic curves E defined over Q with a rational torsion point of exact order N≥ 4;(ii) rank(K2(E))≥1 for all but at most one R-isomorphism class of elliptic curves E defined over Q with a rational torsion point of exact order 3.We give some sufficient conditions for rank(K2(Ez))≥1.

  5. The Yoneda algebra of a K_2 algebra need not be another K_2 algebra

    OpenAIRE

    Cassidy, T.; Phan, Van C.; Shelton, B.

    2008-01-01

    The Yoneda algebra of a Koszul algebra or a D-Koszul algebra is Koszul. K2 algebras are a natural generalization of Koszul algebras, and one would hope that the Yoneda algebra of a K2 algebra would be another K2 algebra. We show that this is not necessarily the case by constructing a monomial K2 algebra for which the corresponding Yoneda algebra is not K2.

  6. The Yoneda algebra of a K_2 algebra need not be another K_2 algebra

    OpenAIRE

    Cassidy, T; Phan, Van C.; Shelton, B.

    2008-01-01

    The Yoneda algebra of a Koszul algebra or a D-Koszul algebra is Koszul. K2 algebras are a natural generalization of Koszul algebras, and one would hope that the Yoneda algebra of a K2 algebra would be another K2 algebra. We show that this is not necessarily the case by constructing a monomial K2 algebra for which the corresponding Yoneda algebra is not K2.

  7. Spitzer v. K2: Part II

    Science.gov (United States)

    Werner, Michael; Crossfield (Deputy PI), Ian; Akeson, Rachel; Beichman, Charles; Benneke, Bjoern; Christiansen, Jessie; Ciardi, David; Deck, Katherine; Dressing, Courtney; Howard, Andrew; Howell, Steve; Knutson, Heather; Krick, Jessica; Livingston, John; Morales, Farisa; Petigura, Erik; Schlieder, Joshua; Gorjian, Varoujan

    2016-08-01

    We propose to build on our Cycles 11-12 program of Spitzer photometry of planets from the K2 survey by enlarging our sample to interesting exoplanets from the continuing K2 mission. Our team has shown that we can carry out this program end to end, starting with finding interesting candidate stars/planets in the K2 data stream, validating them using both proven Kepler techniques and ground-based observations, selecting and executing the Spitzer observations, and analyzing the Spitzer data in conjunction with the K2 data. To date we have observed or scheduled 38 transits/eclipses of 27 exoplanets. We will observe stars in K2 fields 0 through 15 and foresee executing over 60 AOR's on over 40 exoplanets. In the end, we expect to have a greatly improved characterization of exoplanets and their orbits than would be possible from the K2 data alone. This will be vital for JWST follow-up. In addition to improvements in ephemerides, these Spitzer observations will look for transit timing variations, analyze exoplanet atmospheres, study young exoplanets, and provde early TESS follow-up. This work will add substantially to the extensive exoplanet legacy of the Spitzer mission. This is a Generic Target proposal: The fields to be studied and their visibility windows are known, but until the K2 data is analyzed and the targets vetted, we cannot specify exact AORs.

  8. Serendipitous Science from the K2 Mission

    CERN Document Server

    Buzasi, Derek L; Hessler, Carly; Lezcano, Andy; Preston, Heather

    2015-01-01

    The K2 mission is a repurposed use of the Kepler spacecraft to perform high-precision photometry of selected fields in the ecliptic. We have developed an aperture photometry pipeline for K2 data which performs dynamic automated aperture mask selection, background estimation and subtraction, and positional decorrelation to minimize the effects of spacecraft pointing jitter. We also identify secondary targets in the K2 "postage stamps" and produce light curves for those targets as well. Pipeline results will be made available to the community. Here we describe our pipeline and the photometric precision we are capable of achieving with K2, and illustrate its utility with asteroseismic results from the serendipitous secondary targets.

  9. K2 Microlensing and Campaign 9

    Science.gov (United States)

    Penny, Matthew

    2016-06-01

    Campaign 9 of K2 will observe a contiguous 3.7 deg^2 region of the Galactic bulge in order to search for microlensing events and measure microlens parallaxes. It will also perform targeted follow-up of approximately 50 microlensing events spread throughout the Kepler focal plane. Parallax measurements are a critical ingredient for measurements of both the lens mass and distance, which contribute to our understanding of the formation of cold exoplanets, and the formation of planets as a function of Galactic environment. Additionally, as the first un-targeted, space-based microlensing survey, K2C9 offers us the first chance to measure the masses and kinematics of a large population of free-floating planet candidates, whose large abundance has been a puzzle since their discovery.I will review the scientific goals of the K2C9 survey, which will be well underway, and report on the ongoing activity of the K2 Campaign 9 Microlensing Science Team and the wider microlensing community, with a focus on the progress that has been made towards analyzing K2 data in crowded fields.

  10. TRAPPIST-1 photometry with K2

    OpenAIRE

    Luger, Rodrigo; Kruse, Ethan

    2017-01-01

    A static image of the github repository (https://github.com/rodluger/trappist1) used to detrend the K2 light curve of TRAPPIST-1 with the EVEREST pipeline. This code was used to confirm TRAPPIST-1h and detect its period of 18.77 d (https://arxiv.org/abs/1703.04166).

  11. The Structure of Certain K2OF%某些K2OF的结构

    Institute of Scientific and Technical Information of China (English)

    岳勤

    2001-01-01

    In this paper, we investigate the structure of K2OF for F = Q(d), d ≡ -3 mod 9 and d ≠ -3. We find the element of order 3 of K2OF for F = Q( ) and generated elements of K2OF /(2) /(8) /(3) for F = Q( ). We get the property of 2F, which develops a Tate and Bass's theorem, and give the structure of K2Of for F = Q( ) and the presentation relations of SLn(Of)(n 3).%本文研究二次数域F=Q( )的K2Or结构,其中d≡-3 mod 9和d≠-3.找到了关于F=Q( )的K2OF的3阶元和F=Q( )的K2Or的生成元.推广了Bass和Tate的一个定理和给出了F=Q( )的K2OF的结构以及sLn(OF)(n≥3)的表示关系.

  12. PICK2: Planets in Clusters with K2

    Science.gov (United States)

    Cochran, William D.; Endl, Michael; Johnson, Marshall C.; Lee, Byeong-Cheol; Park, Chan; Han, Inwoo; Rauer, Heike; Cabrera, Juan; Csizmadia, Szilard; Paetzold, Martin; Yong, David; Asplund, Martin; Hatzes, Artie P.

    2015-11-01

    Open clusters are remarkable laboratories for a wide variety of astrophysical investigations. They comprise the most homogeneous samples of stars that we can ever hope to find. They are stars that share the same age, initial chemical composition, distance and dynamical environment. The fundamental property that distinguishes one star from another in a cluster is simply the stellar mass. This gives us the very rare opportunity to conduct well controlled astrophysical studies of stars, and as a result there is a vast astronomical literature focused on understanding and characterizing the members of stellar clusters.We are searching for transiting planets in five open clusters in the NASA K2 mission Fields 4, 5 and 7. These clusters range in age from 125My (Pleiades) through the 625My ages of the Hyades and Praesepe, up to the much older Ruprecht 147 (2.5 Gyr) and M67 (3-5 Gyr) clusters. Examination of the distribution of planetary orbital parameters as well as the planetary multiplicity, radius and mass distributions as a function of stellar age (and in comparison with field stars from both K2 and Kepler) will provide a powerful test of theories of planetary system formation and dynamical evolution. The radii of hot Jupiters and Saturns as a function of cluster age will provide a sensitive test of theories to explain the population of inflated hot Jupiters.Our team will process the K2 pixel files into light curves for each target star, and will then search these light curves for possible planet transit events. We will apply standard vetting procedures to remove likely false-positives and we will then model the transit profiles. We will then conduct an extensive set of ground-based follow-up observations using a wide range of observational facilities at our disposal. These will include imaging, high resolution visible and near-IR spectroscopy, precise radial velocity measurement, and ground-based observations of further transits, as appropriate.

  13. El espectro de K2 Vol

    Science.gov (United States)

    Pintado, O. I.; Adelman, S. J.

    Se han obtenido espectros de alta dispersión para la estrella K2 Vol con el espectrógrafo REOSC del CASLEO en un rango de longitudes de ondas comprendido entre 3500 y 5050 Å. El espectro muestra evidencias de que la estrella es binaria. Se determinan las abundancias de los componentes químicos presentes en su atmósfera, como así también algunas características de su compañera.

  14. Measurement of Neutrino Oscillation by the K2K Experiment

    CERN Document Server

    Ahn, M H; Andringa, S; Aoki, S; Aoyama, Y; Argyriades, J; Asakura, K; Ashie, R; Berghaus, F; Berns, H G; Bhang, H; Blondel, A; Borghi, S; Bouchez, J; Boyd, S C; Burguet-Castell, J; Casper, D; Catala, J; Cavata, C; Cervera-Villanueva, Anselmo; Chen, S M; Cho, K O; Choi, J H; Dore, U; Echigo, S; Espinal, X; Fechner, M; Fernández, E; Fujii, K; Fujii, Y; Fukuda, S; Fukuda, Y; Gómez-Cadenas, Juan José; Gran, R; Hara, T; Hasegawa, M; Hasegawa, T; Hayashi, K; Hayato, Y; Helmer, R L; Higuchi, I; Hill, J; Hiraide, K; Hirose, E; Hosaka, J; Ichikawa, A K; Ieiri, M; Iinuma, M; Ikeda, A; Inagaki, T; Ishida, T; Ishihara, K; Ishii, H; Ishii, T; Ishino, H; Ishitsuka, M; Itow, Y; Iwashita, T; Jang, H I; Jang, J S; Jeon, E J; Jeong, I S; Joo, K K; Jover, G; Jung, C K; Kajita, T; Kameda, J; Kaneyuki, K; Kang, B H; Kato, I; Kato, Y; Kearns, E; Kerr, D; Kim, C O; Khabibullin, M; Khotjantsev, A; Kielczewska, D; Kim, B J; Kim, H I; Kim, J H; Kim, J Y; Kim, S B; Kitamura, M; Kitching, P; Kobayashi, K; Kobayashi, T; Kohama, M; Konaka, A; Koshio, Y; Kropp, W; Kubota, J; Kudenko, Yu G; Kume, G; Kuno, Y; Kurimoto, Y; Kutter, T; Learned, J; Likhoded, S; Lim, I T; Lim, S H; Loverre, P F; Ludovici, L; Maesaka, H; Mallet, J; Mariani, C; Martens, K; Maruyama, T; Matsuno, S; Matveev, V; Mauger, C; McConnel Mahn, K B; McGrew, C; Mikheyev, S; Minakawa, M; Minamino, A; Mine, S; Mineev, O V; Mitsuda, C; Mitsuka, G; Miura, M; Moriguchi, Y; Morita, T; Moriyama, S; Nakadaira, T; Nakahata, M; Nakamura, K; Nakano, I; Nakata, F; Nakaya, T; Nakayama, S; Namba, T; Nambu, R; Nawang, S; Nishikawa, K; Nishino, H; Nishiyama, S; Nitta, K; Noda, S; Noumi, H; Nova, F; Novella, P; Obayashi, Y; Okada, A; Okumura, K; Okumura, M; Onchi, M; Oser, S M; Otaki, T; Oyama, Y; Pac, M Y; Park, H; Pierre, F; Rodríguez, A; Saji, C; Sakai, A; Sakuda, M; Sakurai, N; Sánchez, F; Sarrat, A; Sasaki, T; Sato, H; Sato, K; Scholberg, K; Schroeter, R; Sekiguchi, M; Seo, E; Sharkey, E; Shima, A; Shiozawa, M; Shiraishi, K; Sitjes, G; Smy, M B; So, H; Sobel, H; Sorel, M; Stone, J; Sulak, L; Suga, Y; Suzuki, A; Suzuki, Y; Tada, M; Takahashi, T; Takasaki, M; Takatsuki, M; Takenaga, Y; Takenaka, K; Takeuchi, H; Takeuchi, Y; Taki, K; Takubo, Y; Tamura, N; Tanaka, H; Tanaka, K; Tanaka, M; Tanaka, Y; Tashiro, K; Terri, R; T'Jampens, S; Tornero-Lopez, A; Toshito, T; Totsuka, Y; Ueda, S; Vagins, M; Whitehead, L; Walter, C W; Wang, W; Wilkes, R J; Yamada, S; Yamada, Y; Yamamoto, S; Yamanoi, Y; Yanagisawa, C; Yershov, N V; Yokoyama, H; Yokoyama, M; Yoo, J; Yoshida, M

    2006-01-01

    We present measurements of nu_mu disappearance in K2K, the KEK to Kamioka long-baseline neutrino oscillation experiment. One hundred and twelve beam-originated neutrino events are observed in the fiducial volume of Super-Kamiokande with an expectation of 158.1^{+9.2}_{-8.6} events without oscillation. A distortion of the energy spectrum is also seen in 58 single-ring muon-like events with reconstructed energies. The probability that the observations are explained by the expectation for no neutrino oscillation is 0.0015% (4.3sigma). In a two flavor oscillation scenario, the allowed Delta m^2 region at sin^2(2theta) is between 1.9 and 3.5 x 10^{-3} eV^2 at the 90% C.L. with a best-fit value of 2.8 x 10^{-3} eV^2.

  15. K2 & HC 结构学习算法%K2 & HC Structure Learning Algorithm

    Institute of Scientific and Technical Information of China (English)

    吴永广; 庞世春

    2014-01-01

    Bayesian network plays an important role in the field of artificial intelligence .The capability of learning knowledge from data makes it develop rapidly in medicine ,fault diagnosis ,forecasting and other fields .Structure learning al-gorithm of Bayesian network becomes an important research area ,which can effectively analyze dependencies between varia-bles and discover knowledge and data properly .Hill-Climbing strategy can reduce the complex solution space and improve the performance of structure learning algorithm .At the same time ,the K2 algorithm is outstanding on the performance of sco-ring .Combined the scoring function of K2 with the efficient Hill-Climbing strategy ,the K2&HC algorithm is proposed . Meanwhile ,Backtracking principle integrates into the search strategy to solve the problem about the structure learning algo-rithm converging to a local optimum ,which can optimize the performance of the algorithm .Contrast with K2 and K2SA sim-ulation ,the conclusions are made that K2&HC algorithm is outstanding on the comprehensive performance of the accuracy and convergence rate .%贝叶斯网络理论在人工智能领域发挥着重要作用。贝叶斯网络从数据中学习知识的能力使得它在医学、故障诊断、预测等领域的应用迅速发展起来。结构学习算法成为贝叶斯网络的重要研究方向,它能够有效分析变量之间依赖关系,合理挖掘数据和知识。K2算法评分性能突出,而爬山算法能有效弥补K2评分法的解空间过于复杂的问题。论文结合K2评分函数和爬山策略,提出了K2&HC算法。同时,K2&HC算法在爬山策略中融入了回溯原理,解决了贝叶斯结构学习算法中存在的收敛于局部最优的问题,合理优化了算法的性能。同K2K2SA算法进行仿真对比,得出在精度和收敛速度综合性能上K2&HC表现突出的结论。

  16. Synthesis and Photophysical Property Studies of the 2,6,8-Triaryl-4-(phenylethynylquinazolines

    Directory of Open Access Journals (Sweden)

    Malose Jack Mphahlele

    2014-01-01

    Full Text Available The 2-aryl-6,8-dibromo-4-chloroquinazolines derived from the 2-aryl-6,8-dibromoquinazolin-4(3H-ones were subjected to the Sonogashira cross-coupling with terminal acetylenes at room temperature to afford novel 2-aryl-6,8-dibromo-4-(alkynylquinazoline derivatives. Further transformation of the 2-aryl-6,8-dibromo-4-(phenylethynylquinazolines via Suzuki-Miyaura cross-coupling with arylboronic acids occurred without selectivity to afford the corresponding 2,6,8-triaryl-4-(phenylethynylquinazolines. The absorption and emission properties of these polysubstituted quinazolines were also determined.

  17. VizieR Online Data Catalog: K2-30 b and K2-34 b K2 light curves (Lillo-Box+, 2016)

    Science.gov (United States)

    Lillo-Box, J.; Demangeon, O.; Santerne, A.; Barros, S. C. C.; Barrado, D.; Hebrard, G.; Osborn, H. P.; Armstrong, D. J.; Almenara, J.-M.; Boisse, I.; Bouchy, F.; Brown, D. J. A.; Courcol, B.; Deleuil, M.; Delgado Mena, E.; Diaz, R. F.; Kirk, J.; Lam, K. W. F.; McCormac, J.; Pollacco, D.; Rajpurohit, A.; Rey, J.; Santos, N. C.; Sousa, S. G.; Tsantaki, M.; Wilson, P. A.

    2016-10-01

    The star K2-30 (EPIC210957318, 03:29:22.07 +22:17:57.9) was observed by K2 during its campaign 4, between February 7th and April 23rd, 2015. K2-34 (EPIC212110888, 08:30:18.91 +22:14:09.3) belongs to field-of-view 5, photometrically monitored by K2 between April 27th and July 10th, 2015. The data was reduced using both the Warwick (Armstrong et al. 2015A&A...579A..19A, Cat. J/A+A/579/A19) and the LAM- K2 (Barros et al., 2015MNRAS.454.4267B) pipelines. The detrended data (see Tables 1 and 2) show 1.9% and 0.8% dimmings every 4.099 and 2.996 days for K2-30 and K2-34, respectively (see Figs. 1 and 2). (2 data files).

  18. AGN Accretion Physics: Insights from K2

    Science.gov (United States)

    Vogeley, Michael

    We propose to use Kepler K2 mission observations of 1800 supermassive black holes at the centers of galaxies (Active Galactic Nuclei; AGN) to test models for accretion physics, to study the relationship between variability and other AGN properties such as accretion rate, and to guide methods for detecting and classifying AGN in future time-domain surveys. AGN exhibit optical brightness fluctuations on timescales from below an hour up to many years. These fluctuations are determined by the physics of accretion of matter onto black holes from their galactic environment. By observing variability on timescales down to below an hour, Kepler probes the accretion region on length scales that are too small to be directly imaged using conventional telescopes. These data allow us to test competing models for accretion physics that make different predictions for the statistics of variability. Our previous work provides strong evidence that models of AGN variability that work on long timescale data are not adequate to describe the full range of fluctuation timescales probed by Kepler. We will analyze the light curves of 1800 AGN that have been monitored by Kepler during recent and ongoing K2 campaigns. These objects span a large range of luminosity and AGN type, thus allowing study of the relationship between variability and other physical properties. We will characterize the statistics of AGN variability using state-of-the-art methods of time series analysis that are appropriate for quantifying the stochastic behavior of AGN. This analysis builds on our previous work in which we developed and tested new analysis software that extracts the full information content of these light curves and will enable several key outcomes: (1) Measurement of the relationship between types of AGN and their variability. (2) Tests for dependence of variability on accretion rate. (3) Investigation of changes in variability behavior that point to changes in the mode of accretion. (4) Correlations

  19. K2 Variable Catalogue I: A Catalogue of Variable Stars from K2 Field 0

    CERN Document Server

    Armstrong, D J; Brown, D J A; Kirk, J; Lam, K W F; Pollacco, D L; Spake, J; Walker, S R

    2014-01-01

    We have searched the K2 campaign 0 data for lightcurve variations associated with stellar variability. The results of this search are presented as a catalogue, giving the identifiers of nearly 2500 variable stars in the dataset. We list the detected range of the variation, periodicity if relevant and semi-amplitude. Lightcurves are classified into strictly periodic, quasi-periodic and aperiodic groups. We do not attempt to identify the source of variability, which may arise from pulsation or stellar activity. However, we cross match the objects against variable star related guest observer proposals, specifying the variable type in many cases. At present eclipsing binary stars are not included. Future releases will address each K2 field as it is made available, and may be improved to include more detailed catalogue information and to provide detrended object lightcurves.

  20. On K2-group of a Formal Matrix Ring

    Institute of Scientific and Technical Information of China (English)

    Zi Qiang FAN; Zhi Xiang YIN

    2012-01-01

    Let S be a formal matrix ring,T the subring consisting of all diagonal elements,I the set consisting of all off-diagonal elements.Then I is a split radical ideal under certain conditions.In this paper,we show that K2(S) (=) K2(T) ⊕ K2(S,I),and a presentation of K2(S,I) is given.

  1. K2-60b and K2-107b. A Sub-Jovian and a Jovian Planet from the K2 Mission

    Science.gov (United States)

    Eigmüller, Philipp; Gandolfi, Davide; Persson, Carina M.; Donati, Paolo; Fridlund, Malcolm; Csizmadia, Szilard; Barragán, Oscar; Smith, Alexis M. S.; Cabrera, Juan; Korth, Judith; Grziwa, Sascha; Prieto-Arranz, Jorge; Nespral, David; Saario, Joonas; Cochran, William D.; Cusano, Felice; Deeg, Hans J.; Endl, Michael; Erikson, Anders; Guenther, Eike W.; Hatzes, Artie P.; Pätzold, Martin; Rauer, Heike

    2017-03-01

    We report the characterization and independent detection of K2-60b, as well as the detection and characterization of K2-107b, two transiting hot gaseous planets from the K2 space mission. We confirm the planetary nature of the two systems and determine their fundamental parameters combining the K2 time-series data with FIES@NOT and HARPS-N@TNG spectroscopic observations. K2-60b has a radius of 0.683 ± 0.037 R Jup and a mass of 0.426 ± 0.037 M Jup and orbits a G4 V star with an orbital period of 3.00267 ± 0.00006 days. K2-107b has a radius of 1.44 ± 0.15 R Jup and a mass of 0.84 ± 0.08 M Jup and orbits an F9 IV star every 3.31392 ± 0.00002 days. K2-60b is among the few planets at the edge of the so-called “desert” of short-period sub-Jovian planets. K2-107b is a highly inflated Jovian planet orbiting an evolved star about to leave the main sequence.

  2. K2P2- A photometry pipeline for the K2 mission

    DEFF Research Database (Denmark)

    Lund, Mikkel N.; Handberg, Rasmus; Davies, Guy R.;

    2015-01-01

    With the loss of a second reaction wheel, resulting in the inability to point continuously and stably at the same field of view, the NASA Kepler satellite recently entered a new mode of observation known as the K2 mission. The data from this redesigned mission present a specific challenge; the ta...... for multiple targets increases the amount of potential light curves by a factor ${\\geq}10$. Our pipeline could be applied to the upcoming TESS (Ricker et al. 2014) and PLATO 2.0 (Rauer et al. 2013) missions....

  3. K2P$^2$ $-$ A photometry pipeline for the K2 mission

    CERN Document Server

    Lund, Mikkel N; Davies, Guy R; Chaplin, William J; Jones, Caitlin D

    2015-01-01

    With the loss of a second reaction wheel, resulting in the inability to point continuously and stably at the same field of view, the NASA Kepler satellite recently entered a new mode of observation known as the K2 mission. The data from this redesigned mission present a specific challenge; the targets systematically drift in position on a ~6 hour time scale, inducing a significant instrumental signal in the photometric time series --- this greatly impacts the ability to detect planetary signals and perform asteroseismic analysis. Here we detail our version of a reduction pipeline for K2 target pixel data, which automatically: defines masks for all targets in a given frame; extracts the target's flux- and position time series; corrects the time series based on the apparent movement on the CCD (either in 1D or 2D) combined with the correction of instrumental and/or planetary signals via the KASOC filter (Handberg & Lund 2014), thus rendering the time series ready for asteroseismic analysis; computes power s...

  4. Your Child's Development: 3-5 Days

    Science.gov (United States)

    ... for TV, Video Games, and the Internet Your Child’s Development: 3-5 Days KidsHealth > For Parents > Your Child’s Development: 3-5 Days Print A A A en ... the sole of the foot Social and Emotional Development soothed by a ... When to Talk to Your Doctor Every child develops at his or her own pace, but ...

  5. Cleanup Verification Package for the 116-K-2 Effluent Trench

    Energy Technology Data Exchange (ETDEWEB)

    J. M. Capron

    2006-04-04

    This cleanup verification package documents completion of remedial action for the 116-K-2 effluent trench, also referred to as the 116-K-2 mile-long trench and the 116-K-2 site. During its period of operation, the 116-K-2 site was used to dispose of cooling water effluent from the 105-KE and 105-KW Reactors by percolation into the soil. This site also received mixed liquid wastes from the 105-KW and 105-KE fuel storage basins, reactor floor drains, and miscellaneous decontamination activities.

  6. Elements of Small Orders in K2F Ⅱ

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In "Elements of small orders in K2(F)" (Algebraic K-Theory, Lecture Notes in Math., 966, 1982, 1-6.), the author investigates elements of the form {a, Φn(a)} in the Milnor group K2F of a field F, where Φn(x) is the n-th cyclotomic polynomial. In this paper, these elements are generalized. Applying the explicit formulas of Rosset and Tate for the transfer homomorphism for K2, the author proves some new results on elements of small orders in K2F.

  7. Synthesis, characterization, stereochemistry and antibacterial activity of N-acyl-2,4,6,8-tetraphenyl-3,7-diazabicyclo[3.3.1]nonanes

    Science.gov (United States)

    Ponnuswamy, S.; Pushpalatha, S.; Akila, A.; Raghuvarman, B.; Aravindhan, S.

    2016-12-01

    Three new N-acyl-2,4,6,8-tetraphenyl-3,7-diazabicyclo[3.3.1]nonanes 3-5 have been synthesized. The structural characterization and the conformational preferences of the compounds 3-5 have been carried out using IR, 1D and 2D NMR spectral data. The NMR spectral data indicate that the N-acyl-2,4,6,8-tetraphenyl-3,7-diazabicyclo[3.3.1]nonanes 3-5 prefer to exist in twin-chair conformation with partial flattening at amide nitrogen end. In order to avoid A1,3-strain with coplanar acyl groups, the phenyl groups at the amide nitrogen end are forced to occupy axial orientation. X-ray crystal structure of the N-dichloroacetyl-2,4,6,8-tetraphenyl-3,7-diazabicyclo[3.3.1]nonane 4 also supports the twin-chair conformation in the solid state. Furthermore, the antibacterial activity for the compounds 2-5 has been carried out.

  8. Preparation QTi3.5-3.5 Graphite Lubricant Material with Semi-solid Casting Technology

    Institute of Scientific and Technical Information of China (English)

    Peng ZHANG; Yunhui DU; Daben ZENG; Jianzhong CUI; Limin BA

    2001-01-01

    For the first time, the distribution of graphite particles in QTi3.5-3.5 graphite ingot was studied by using semi-solid casting technology. The results show that: the relationship between solid fraction and stirring temperature of QTi3.5-3.5 graphite slurry is y=759.4-0.711x (where y is solid fraction, x is stirring temperature). With the increasing of solid fraction of QTi3.5-3.5 graphite slurry, the agglomeration of graphite particles in ingot reduces gradually. The condition to prepare QTi3.5-3.5 graphite lubricant material with even distribution of graphite particles is that the solid fraction of QTi3.5-3.5 graphite slurry is larger than 40%.

  9. An overview on importance, synthetic strategies and studies of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (HNIW

    Directory of Open Access Journals (Sweden)

    J. Venkata Viswanath

    2016-10-01

    Full Text Available 2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (HNIW, commonly called as CL-20, is a high energy and high density material of keen interest to both commercial and scientific worlds due to its greater insensitivity (reduced sensitivity along with a positive high heat of formation, which is due to the azanitro groups attached to the skeleton of HNIW and its highly strained cage structure. It plays a remarkable role in modification and replacement of most of the propellant (gun and rocket preparations. In this report we present the comparative strategies involved in the syntheses of HNIW with respect to economical and environmental aspects. Various methods reported in the literature on the purification of the crude HNIW (α-HNIW to obtain ε-form of HNIW (high dense/more potential are consolidated. Understanding of the structure, morphology, energetics, thermal behavior and their modification to meet the applicability (decreased impact sensitivity determines the industrial application of HNIW. A compilation of the available literature on the aforementioned characteristic properties for obtaining a value added ε-HNIW is discussed here. This overview also reports the literature available on newer forms of HNIW including derivatives and cocrystals, which increase the performance of HNIW.

  10. 10-Formyl-2,4,6,8,12-pentanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05,9.03,11]dodecane acetone solvate

    Directory of Open Access Journals (Sweden)

    Huaxiong Chen

    2010-02-01

    Full Text Available The title compound, C7H7N11O11·C3H6O, consisting of one molecule of 10-formyl-2,4,6,8,12-pentanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05,9.03,11]dodecane (pentanitromonoformylhexaazaisowurtzitane, PNMFIW and one acetone solvent molecule, is a member of the caged hexaazaisowurtzitane family. PNMFIW has a cage structure which is constructed from one six-membered and two five-membered rings which are linked by a C—C bond, thus creating two seven-membered rings. In the PNMFIW molecule, one formyl group is bonded to the N heteroatom of the six-membered cycle, and five nitro groups are appended to other five N heteroatom of the caged structure. The acetone solvent molecule is arranged beside a five-membered plane of PNMFIW with an O atom and an H atom close (with respect to the sum of the van der Waals radii to the neighbouring nitro O atom [O...O = 2.957 (3 and 2.852 (3 Å; O... H = 2.692 (2, 2.526 (3 and 2.432 (3 Å].

  11. Measurement of Branching Fractions for B0 ->K*2(1430)0 gamma and B+ -> K*2(1430)+ gamma

    CERN Document Server

    Aubert, Bernard; Abe, T; Abrams, G S; Adye, T; Ahmed, S; Alam, M S; Albert, J; Aleksan, Roy; Allison, J; Altenburg, D; Andreotti, M; Angelini, C; Anulli, F; Aston, D; Azzolini, V; Baak, M A; Back, J J; Bailey, S; Baldini-Ferroli, R; Band, H R; Banerjee, Sw; Barate, R; Barlow, N R; Barlow, R J; Bartoldus, R; Batignani, G; Bauer, J M; Beck, T W; Behera, P K; Bellini, F; Benayoun, M; Berger, N; Beringer, J; Bernard, D; Berryhill, J W; Best, D; Bettarini, S; Bettoni, D; Bevan, A J; Bhimji, W; Bianchi, F; Biasini, M; Blanc, F; Blaylock, G; Blinov, V E; Bloom, P; Bondioli, M; Bonneaud, G R; Borean, C; Borgland, A W; Bosisio, L; Boutigny, D; Bowerman, D A; Boyarski, A M; Boyd, J T; Bozzi, C; Brandt, T; Brau, B; Brau, J E; Breon, A B; Briand, H; Brigljevic, V; Brochard, F; Brose, J; Brown, C L; Brown, C M; Brown, D; Brown, D N; Bruinsma, M; Brunet, S; Bucci, F; Buchanan, C; Buchmüller, O L; Bugg, W; Bukin, A D; Burchat, Patricia R; Button-Shafer, J; Buzzo, A; Bóna, M; Cahn, R N; Calabrese, R; Calcaterra, A; Calderini, G; Campagnari, C; Capra, R; Carpinelli, M; Cartaro, C; Cavallo, N; Cavoto, G; Chao, M; Charles, E; Chauveau, J; Chen, E; Chen, J C; Chen, S; Cheng, C H; Chevalier, N; Christ, S; Cibinetto, G; Clark, P J; Cochran, J; Cohen-Tanugi, J; Colberg, T; Colecchia, F; Coleman, J P; Contri, R; Convery, M R; Cote-Ahern, D; Cottingham, W N; Coupal, D P; Cowan, G; Cowan, R; Crawley, H B; Cremaldi, L M; Crosetti, G; Dahmes, B; Dallapiccola, C; Danielson, N; Dasu, S; Datta, M; Dauncey, P D; David, P; Davier, M; Davis, C L; Day, C T; De Groot, N; De Nardo, Gallieno; De Sangro, R; Del Buono, L; Del Gamba, V; Del Re, D; Della Ricca, G; Di Lodovico, F; Dickopp, M; Dittongo, S; Dong, D; Dorfan, J; Dorigo, A; Dubitzky, R S; Dubois-Felsmann, G P; Dujmic, D; Dunwoodie, W M; Dvoretskii, A; Eckmann, R; Edwards, A J; Egede, U; Eichenbaum, A M; Eigen, G; Eisner, A M; Elmer, P; Emery, S; Ernst, J A; Eschenburg, V; Eschrich, I; Fabozzi, F; Faccini, R; Falciai, D; Farbin, A; Ferrarotto, F; Ferroni, F; Field, R C; Finocchiaro, G; Flack, R L; Flächer, H U; Flood, K T; Ford, K; Ford, W T; Forti, A C; Forti, F; Fortin, D; Franek, B J; Frey, R; Fry, J R; Gabathuler, Erwin; Gabriel, T A; Gaidot, A; Gaillard, J M; Gaillard, J R; Galeazzi, F; Gallo, F; Gamba, D; Gamet, R; Gan, K K; Ganzhur, S F; Gaspero, M; Gatto, C; Geddes, N I; George, S; Gill, M S; Giorgi, M A; Giraud, P F; Gladney, L; Glanzman, T; Godang, R; Goetzen, K; Golubev, V B; Gopal, G P; Gowdy, S J; Grancagnolo, S; Graugès-Pous, E; Green, M G; Grenier, G J; Grenier, P; Gritsan, A V; Grosdidier, G; Groysman, Y; Guo, Q H; Hadavand, H K; Hadig, T; Haire, M; Halyo, V; Hamel de Monchenault, G; Hamon, O; Harrison, P F; Harrison, T J; Hart, P A; Hartfiel, B L; Harton, J L; Hast, C; Hauke, A; Hawkes, C M; Hearty, C; Held, T; Hertzbach, S S; Heusch, C A; Hicheur, A; Hill, E J; Hitlin, D G; Hodgkinson, M C; Honscheid, K; Hrynóva, T; Hu, T; Hufnagel, D; Höcker, A; Innes, W R; Ivanchenko, V N; Izen, J M; Jackson, F; Jackson, P D; Jacobsen, R G; Jawahery, A; Jayatilleke, S M; Jessop, C P; John, M J J; Johnson, J R; Judd, D; Kadel, R W; Kadyk, J; Kagan, H; Karyotakis, Yu; Kass, R; Kay, M; Kelly, M P; Kelsey, M H; Kerth, L T; Khan, A; Kim, H; Kim, P; Kirkby, D; Kitayama, I; Knowles, D J; Koch, H; Kocian, M L; Kofler, R; Kolomensky, Yu G; Koptchev, V B; Kovalskyi, D; Kowalewski, R V; Kozanecki, Witold; Kral, J F; Kravchenko, E A; Krishnamurthy, M; Kroeger, R; Kukartsev, G; Kurup, A; Kutter, P E; Kuznetsova, N; Kyberd, P; La Vaissière, C de; Lacker, H M; Lae, C K; Lafferty, G D; Lamsa, J; Lanceri, L; Lange, D J; Langenegger, U; Langer, M; Lankford, A J; Laplace, S; Latham, T E; Lavin, D; Lazzaro, A; Le Clerc, C; Le Diberder, F R; Lee, S J; Lees, J P; Legendre, M; Leith, D W G S; Lepeltier, V; Leruste, P; Levesque, J A; Levi, M E; Levy, S L; Lewandowski, B; Li, H; Lillard, V; Lista, L; Liu, R; Lo Vetere, M; LoSecco, J M; Lockman, W S; London, G W; Long, O; Lou, X C; Lu, A; Luitz, S; Luppi, E; Lusiani, A; Lutz, A M; Lynch, G; Lynch, H L; Lyon, A J; Lü, C; Lüth, V; MacFarlane, D B; MacKay, C; Macri, M; Mallik, U; Maly, E; Mancinelli, G; Mandelkern, M A; Manfredi, P F; Mangeol, D J J; Marchiori, G; Margoni, M; Marker, C E; Marsiske, H; Martínez-Vidal, F; Mattison, T S; Mayer, B; Mazur, M A; Mazzoni, M A; McKemey, A K; McKenna, J A; McMahon, T R; Meadows, B T; Messner, R; Meyer, T I; Meyer, W T; Miftakov, V; Mihályi, A; Mir, L M; Mohapatra, A K; Mommsen, R K; Monge, M R; Moore, T B; Morandin, M; Morgan, S E; Morganti, M; Morganti, S; Morii, M; Morton, G W; Muheim, F; Müller, D R; Müller-Pfefferkorn, R; Narsky, I; Nash, J A; Nauenberg, U; Neal, H; Negrini, M; Neri, N; Nicholson, H; Nogowski, R; O'Grady, C P; Ocariz, J; Oddone, P J; Ofte, I; Olaiya, E O; Olivas, A; Olsen, J; Onuchin, A P; Orimoto, T J; Otto, S; Ozcan, V E; Paar, H P; Paick, K; Palano, A; Palombo, F; Pan, Y; Panetta, J; Panvini, R S; Paoloni, E; Paolucci, P; Parry, R J; Passaggio, S; Patel, P M; Patrignani, C; Patteri, P; Payne, D J; Pelizaeus, M; Penny, R C; Perazzo, A; Perl, M; Peruzzi, I M; Peters, K; Petersen, B A; Petersen, T C; Petrak, S; Piccolo, D; Piccolo, M; Piemontese, L; Pierini, M; Pioppi, M; Piredda, G; Pivk, M; Plaszczynski, S; Playfer, S; Pompili, A; Poropat, P; Porter, F C; Posocco, M; Potter, C T; Prell, S; Prepost, R; Pripstein, M; Pulliam, T; Purohit, M V; Qi, N D; Rahatlou, S; Rama, M; Rankin, P; Ratcliff, B N; Raven, G; Re, V; Reidy, J; Ricciardi, S; Richman, J D; Ritchie, J L; Rizzo, G; Roat, C; Robbe, P; Roberts, D A; Robertson, S H; Robutti, E; Roe, N A; Romosan, A; Ronan, Michael T; Roney, J M; Rong, G; Roodman, A; Roos, L; Rosenberg, E I; Rotondo, M; Roy, J; Ryd, A; Röthel, W; Safai-Tehrani, F; Saleem, M; Salnikov, A A; Salvatore, F; Samuel, A; Sanders, D A; Sanders, P; Sandrelli, F; Santroni, A; Saremi, S; Sarti, A; Schalk, T; Schindler, R H; Schmitz, R E; Schmücker, H; Schott, G; Schubert, J; Schubert, Klaus R; Schumm, B A; Schune, M H; Schwiening, J; Schwierz, R; Schwitters, R F; Sciacca, C; Sciolla, G; Seiden, A; Sekula, S J; Serednyakov, S I; Sharma, V; Shelkov, V G; Shen, B C; Shorthouse, H W; Simi, G; Simonetto, F; Sinev, N B; Skovpen, Yu I; Sloane, R J; Smith, A J S; Smith, J G; Snyder, A; Soffer, A; Soha, A; Sokoloff, M D; Solodov, E P; Spaan, B; Spanier, S M; Stark, J; Steinke, M; Stelzer, J; Stoker, D P; Stroili, R; Strom, D; Strother, P; Stugu, B; Stängle, H; Su, D; Sullivan, M K; Summers, D J; Swain, J E; T'Jampens, S; Tanaka E W; Tantot, L; Taras, P; Taylor, F; Taylor, G P; Telnov, A V; Therin, G; Thiebaux, C; Thiessen, D; Tiozzo, G; Tisserand, V; Toki, W H; Torrence, E; Tosi, S; Touramanis, C; Treadwell, E; Turri, M; Vaitsas, G; Van Hoek, W C; Varnes, H A; Vasileiadis, G; Vasseur, G; Vavra, J; Verderi, M; Verkerke, W; Vidal, P B; Vitale, L; Voci, C; Voena, C; Von, J H; Vuagnin, G; Wagner, G; Wagner, S R; Wagoner, D E; Waldi, R; Walkowiak, W; Walsh, J; Wang, P; Wappler, F R; Watson, A T; Watson, N K; Weatherall, J H; Weaver, M; Weidemann, A W; Weinstein, A J R; Wenzel, W A; Wilden, L; Williams, D C; Williams, J C; Willocq, S; Wilson, F F; Wilson, M G; Wilson, R J; Winter, M A; Wisniewski, W J; Won, E; Wong, Q K; Wormser, G; Wright, D H; Wright, D M; Wu Sau Lan; Wu, J; Xella, S M; Yamamoto, R K; Yang, S; Ye, S; Yi, J; Young, C C; Yu, Z; Yumiceva, F X; Yushkov, A N; Yéche, C; Zallo, A; Zghiche, A; Zhang, J; Zhang, L; Zhao, H W; Zhu, Y S; Zito, M; Çuhadar-Dönszelmann, T

    2003-01-01

    We have investigated the exclusive, radiative B-meson decay to K_2^*(1430) in 88.5 * 10^6 BBbar events. We present a preliminary measurement of the branching fractions BR(B->K^*_2(1430)^0 gamma) = (1.22+-0.25+-0.11) * 10^{-5} and BR(B->K^*_2(1430)^+ gamma) = (1.44+-0.40+-0.13) * 10^{-5}.

  12. Medium optimization to improve astaxanthin production of Xanthophyllomyces dendrorhous mutant W6-8 based on genetic algorithms

    Institute of Scientific and Technical Information of China (English)

    WangWenjun; YuLongjiang; HePu; ZhouPengpeng

    2004-01-01

    Genetic algorithms (GA) based on the principle of mimicing Darwinian evolution and survival of the fittest in a natural environment was used to optimize the medium for astaxanthin production by the mutant strain W6-8 of Xantho-phyllomyces dendrorhous. The 50 concentration levels of 6 medium components were optimized within 50 experiments (full experimental plan: 506 experiments). The results showed that GA could be applied in the medium optimization and better results were obtained. By employing optimized medium components (glucose 39.8 g l-1, yeast extract 4.08 g l-1,(NH4)2SO4 7.36 g l-1, MgSO4 2 g l-1, K2HPO4 2.04 g l-1 and KH2PO4 3.48 g l-1), the highest astaxanthin production was 9.855 mg l-1, approximately 31% higher than that under the initial conditions, and was approximately 15.46% higher than that by orthogonal array but only slightly higher than that by response surface methodology. In the sequent scale-up experiments, the astaxanthin yield was obtained approximately 14.753 mg l-1, employing the optimal medium. The results indicated that GA, as an euiicient method for medium optimization, was superior to other optimal means such as orthogonal array.

  13. International Space Station: 6-8 Hands-on Science and Math Lesson Plans.

    Science.gov (United States)

    Armstrong, Pat

    These lesson plans, designed for grades 6-8, have been developed to provide a guide to hands-on experience in science and math. They focus on an International Space Station and are designed for use with students working in groups. The three lesson plans highlighting the importance of the scientific method are: (1) International Space Station…

  14. 36 CFR 6.8 - National Park Service solid waste responsibilities.

    Science.gov (United States)

    2010-07-01

    ..., DEPARTMENT OF THE INTERIOR SOLID WASTE DISPOSAL SITES IN UNITS OF THE NATIONAL PARK SYSTEM § 6.8 National Park Service solid waste responsibilities. (a) Beginning one year after January 23, 1995, a Superintendent will not permit or allow a person to dispose of solid waste at a National Park Service...

  15. State of Delaware Science Curriculum Framework Content Standards [and] Performance Indicators, 6-8.

    Science.gov (United States)

    Delaware State Dept. of Education, Dover.

    Part of the Delaware Department of Education's ongoing efforts to provide assistance and support to local school districts in their development of a standards-based curriculum, this document presents the eight science standards for middle school. The standards for grades 6-8 are: (1) nature and application of science and technology; (2) materials…

  16. Supporting English Language Learners in Math Class, Grades 6-8

    Science.gov (United States)

    Melanese, Kathy; Chung, Luz; Forbes, Cheryl

    2011-01-01

    This new addition to Math Solutions "Supporting English Language Learners in Math Class series" offers a wealth of lessons and strategies for modifying grades 6-8 instruction. Section I presents an overview of teaching math to English learners: the research, the challenges, the linguistic demands of a math lesson, and specific strategies and…

  17. It's All Connected: The Power of Proportional Reasoning to Understand Mathematics Concepts, Gr. 6-8

    Science.gov (United States)

    Whitman, Carmen

    2011-01-01

    "It's All Connected" provides teachers of mathematics the support they need to improve their instruction. This in-demand collection of lessons for grades 6-8 explores proportionality, proportional relationships, and proportional reasoning, acknowledging that the ability to reason proportionally is crucial in the middle school mathematics…

  18. Quasi-periodic Solutions to the K(-2, -2) Hierarchy

    Science.gov (United States)

    Wu, Lihua; Geng, Xianguo

    2016-07-01

    With the help of the characteristic polynomial of Lax matrix for the K(-2, -2) hierarchy, we define a hyperelliptic curve 𝒦n+1 of arithmetic genus n+1. By introducing the Baker-Akhiezer function and meromorphic function, the K(-2, -2) hierarchy is decomposed into Dubrovin-type differential equations. Based on the theory of hyperelliptic curve, the explicit Riemann theta function representation of meromorphic function is given, and from which the quasi-periodic solutions to the K(-2, -2) hierarchy are obtained.

  19. Algebra task sheets : grades 3-5

    CERN Document Server

    Reed, Nat

    2009-01-01

    For grades 3-5, our Common Core State Standards-based resource meets the algebraic concepts addressed by the NCTM standards and encourages the students to learn and review the concepts in unique ways. Each task sheet is organized around a central problem taken from real-life experiences of the students.

  20. Geometry task sheets : grades 3-5

    CERN Document Server

    Rosenberg, Mary

    2009-01-01

    For grades 3-5, our Common Core State Standards-based resource meets the geometry concepts addressed by the NCTM standards and encourages the students to learn and review the concepts in unique ways. Each task sheet is organized around a central problem taken from real-life experiences of the students.

  1. Planet Occurrence Rates for K2 M Dwarfs

    Science.gov (United States)

    Manideep Duvvuri, Girish; Dressing, Courtney D.; Knutson, Heather

    2017-01-01

    M dwarfs comprise the vast majority of stars in the galaxy, and so their planet populations are of particular interest. Kepler observed a few thousand early M dwarfs and now K2 has observed more than 10,000 low mass cool stars ranging in spectral type from late K to mid M. The short orbital period of planets in the habitable zones for these low-mass, cool stars makes them prime targets for transit spectroscopy and detectable within an 80 day K2 campaign. To calculate the occurrence rate, we must identify all the M dwarfs K2 has observed, which is observationally expensive to do spectroscopically for all ~160,000 stars so far and the thousands to follow. Using photometry from the spectroscopically classified targets of the Kepler mission, we train a Random Forest classifier to categorize the K2 targets using only their available photometry. We determine the probability of each K2 target being an M dwarf such that we can calculate the planet occurrence rate using the entire sample while accounting for the uncertainty of our classification method. As surveys provide more spectroscopic and photometric information for these K2 targets, the Random Forest can be re-trained and improved. The classifier can be used for all subsequent K2 campaigns and potentially be modified for TESS targets, giving it long-term applicability. For 115 planet candidates detected orbiting 17612 cool dwarfs observed during K2 C0-8, we calculate a cool dwarf planet occurrence rate of 1.4 for P < 80 days, biased toward small (< 3 REarth) planets with P < 50 days.

  2. Investigation of the Mitochondrial ATPase 6/8 and tRNALys Genes Mutations in Autism

    OpenAIRE

    Sepideh Dadgar; Zahra-Soheila Soheili; Omid Aryani; Massoud Houshmand; Fahimeh Piryaei

    2012-01-01

    Objective: Autism results from developmental factors that affect many or all functional brain systems. Brain is one of tissues which are crucially in need of adenosine triphosphate (ATP). Autism is noticeably affected by mitochondrial dysfunction which impairs energy metabolism. Considering mutations within ATPase 6, ATPase 8 and tRNALys genes, associated with different neural diseases, and the main role of ATPase 6/8 in energy generation, we decided to investigate mutations on these mtDNA-en...

  3. Five strands of math drills big book : grades 6-8

    CERN Document Server

    Reed, Nat; Forest, Chris

    2011-01-01

    For grades 6-8, our Common Core State Standards-based resource meets the five strands of math concepts addressed by the NCTM standards and encourages the students to review the concepts in unique ways. Included are warm-up and timed drill activities which will push the boundaries of critical thought and demonstrate to students the importance of mathematical problems in Number & Operations, Geometry, Measurement, Data Analysis & Probability and Algebra using real world situations.

  4. Common Core Literacy Lesson Plans: Ready-to-Use Resources, 6-8

    Science.gov (United States)

    Davis, Lauren

    2013-01-01

    Schools nationwide are transitioning to the Common Core--our advice to you: Don't go it alone! Our new book, "Common Core Literacy Lesson Plans: Ready-to-Use Resources, 6-8," shows you that teaching the Common Core State Standards in the middle grades doesn't have to be intimidating! This easy-to-use guide meets the particular needs of middle…

  5. Hydrostatic Compression of 2,4,6,8,10,12 hexanitrohexaaza isowurtzitane (CL20) Co Crystals

    Science.gov (United States)

    2016-12-01

    improved properties.1,2 Co-crystals are solid state materials comprising 2 (or more) molecular components that interact via noncovalent interactions...of the co-crystal’s stability to that of the individual components .6,7 However, other critical material properties such as the response of EM co...Hydrostatic Compression of 2,4,6,8,10,12- hexanitrohexaaza-isowurtzitane (CL20) Co-Crystals by DeCarlos Taylor Weapons and Materials

  6. Crossing number of K2,3 ∨ Pn%K2,3 ∨ Pn的交叉数

    Institute of Scientific and Technical Information of China (English)

    苏振华; 黄元秋

    2012-01-01

    Few results are known on the crossing numbers of join product for graphs having five vertices with paths. The research in this aspect is deepened, and it is determined that the crossing number of K2,3 V Pn and {K2,3 + e} V Pn is Z(5, n) + n + 1.%已经确定的五阶图与路Pn的联图的交叉数较少,作者继续深化这方面的研究,得到了联图K2,3 V Pn与{K2,3+e}V Pn的交叉数为Z(5,n)+n+1.

  7. Prevalence and Properties of Planets from Kepler and K2

    Science.gov (United States)

    Petigura, Erik; Marcy, Geoffrey W.; Howard, Andrew; Crossfield, Ian; Beichman, Charles; Sinukoff, Evan

    2015-12-01

    Discoveries from the prime Kepler mission demonstrated that small planets (formation around G, K, and M stars. While Kepler detected many such planets, all but a handful orbit faint, distant stars, which are not amenable to precise follow up measurements. NASA's K2 mission has the potential to increase the number of known small, transiting planets around bright stars by an order of magnitude. I will present the latest results from my team's efforts to detect, confirm, and characterize planets using the K2 mission. I will highlight some of the progress and remaining challenges involved with generating denoised K2 photometry and with detecting planets in the presence of severe instrument systematics. Among our recent discoveries are the K2-3 and K2-21 planetary systems: M dwarfs hosting multiple transiting Earth-size planets with low equilibrium temperatures. These systems offer a convenient laboratory for studying the bulk composition and atmospheric properties of small planets receiving low levels of stellar irradiation, where processes such as mass loss by photo-evaporation could play a weaker role.

  8. DAVE: Discovery and Vetting of K2 Exoplanets

    Science.gov (United States)

    Coughlin, Jeffrey; Mullally, Fergal; Mullally, Susan; Colón, Knicole D.; Barentsen, Geert; Quintana, Elisa V.; Burke, Christopher J.; Barclay, Thomas

    2016-06-01

    NASA's K2 mission is capable of finding planets as small as the Earth around bright, nearby stars. These targets are well-suited for JWST follow-up to study their density and atmospheric composition. Such observations will yield a better understanding of the difference between rocky and gaseous planets, particularly how composition varies as a function of radius. K2 observes over 10,000 stars every 90 days, which coupled with significant systematics due to spacecraft pointing jitter, presents a challenge in rapidly detecting high-quality planet candidates. In this talk, we present results from our Discovery and Vetting of K2 Exoplanets (DAVE) team. DAVE focuses on applying robotic vetting techniques, formulated as part of the prime Kepler mission, to possible K2 planets detected by both DAVE and other teams. We highlight these robotic vetting techniques and the types of false positives they eliminate, and present examples of well-vetted candidates. We make the DAVE pipeline, including the vetting tools, publicly available at http://github.com/barentsen/dave. This work is funded by a K2 Guest Observer Cycle 2 grant.

  9. Dermal Sensitization of 1-Acetyloctahydro-3,5,7-Trinitro-1,3,5,7-Tetrazocine.

    Science.gov (United States)

    1984-08-08

    tetrazocine (SEX) in guinea pigs MATERIALS Test Substance Chemical name: 1-Acetyloctahydro-3,5,7-Trinitro-I,3,5,7- Tetrazocine (SEX) Chemical Abstract Service...exist as a contaminant in P.DX/HMX manufacturing process. The characteristics of SEX are as follows: Chemical Abstract Service Registry No.: 13980-00-2

  10. ZEIT: Searching for Young Stars in K2

    Science.gov (United States)

    Morris, Nathan; Mann, Andrew W.

    2017-01-01

    Nearby young, open clusters such as the Hyades, Pleiades, and Praesepe provide an important reference point for the properties of stellar systems in general. In each cluster, all stars are of the same known age. As such, observations of planetary systems around these stars can be used to gain insight into the early stages of planetary system formation. K2, the revived Kepler mission, has provided a vast number of light curves for young stars in the clusters and elsewhere in the K2 field. We aim to compute rotational periods from sunspot patterns for all K2 target stars and use gyrochronometric relationships derived from cluster stars to determine their ages. From there, we will search for planets around young stars outside the clusters with the ultimate goal of shedding light on how planets and planetary systems evolve with time.

  11. Studying RR Lyrae Stars in M4 with K2

    Science.gov (United States)

    Kuehn, Charles A.; Drury, Jason; Moskalik, Pawel

    2017-01-01

    Observations by Kepler/K2 have revolutionized the study of RR Lyrae stars by allowing the detection of new phenomena, such as low amplitude additional modes and period doubling, which had not previously been seen from the ground. During its campaign 2, K2 observed the globular cluster M4, providing the first opportunity to study a sizeable group of RR Lyrae stars that belong to a single population; the other RR Lyrae stars that have been observed from space are field stars in the galactic halo and thus belong to an assortment of populations. We present the results of our study of the RR Lyrae variables in M4 from K2 photometry. We have identified additional, low amplitude pulsation modes in the two observed RRc stars. In three RRab stars we have found the Blazhko effect with periods of 16.6 days, 22.4 days, and 44.5 days.

  12. Asteroseismology of solar-type stars with K2

    CERN Document Server

    Chaplin, W J; Handberg, R; Basu, S; Buchhave, L A; Campante, T L; Davies, G R; Huber, D; Latham, D W; Latham, C A; Serenelli, A; Antia, H M; Appourchaux, T; Ball, W H; Benomar, O; Casagrande, L; Christensen-Dalsgaard, J; Coelho, H R; Creevey, O L; Elsworth, Y; Garc, R A; Gaulme, P; Hekker, S; Kallinger, T; Karoff, C; Kawaler, S D; Kjeldsen, H; Lundkvist, M S; Marcadon, F; Mathur, S; Miglio, A; Mosser, B; R, C; Roxburgh, I W; Aguirre, V Silva; Stello, D; Verma, K; White, T R; Bedding, T R; Barclay, T; Buzasi, D L; Deheuvels, S; Gizon, L; Houdek, G; Howell, S B; Salabert, D; Soderblom, D R

    2015-01-01

    We present the first detections by the NASA K2 Mission of oscillations in solar-type stars, using short-cadence data collected during K2 Campaign\\,1 (C1). We understand the asteroseismic detection thresholds for C1-like levels of photometric performance, and we can detect oscillations in subgiants having dominant oscillation frequencies around $1000\\,\\rm \\mu Hz$. Changes to the operation of the fine-guidance sensors are expected to give significant improvements in the high-frequency performance from C3 onwards. A reduction in the excess high-frequency noise by a factor of two-and-a-half in amplitude would bring main-sequence stars with dominant oscillation frequencies as high as ${\\simeq 2500}\\,\\rm \\mu Hz$ into play as potential asteroseismic targets for K2.

  13. Some Elements of Finite Order in K2Q

    Institute of Scientific and Technical Information of China (English)

    Xiao Yun CHENG; Jian Guo XIA; Hou Rong QIN

    2007-01-01

    Let K2 be the Milnor functor and let Фn(x) ∈ Q[x] be the n-th cyclotomic polynomial. Let Gn(Q) denote a subset consisting of elements of the form {a, Фn(a)}, where a ∈ Q* and {, } denotes the Steinberg symbol in K2Q. J. Browkin proved that Gn (Q) is a subgroup of K2Q if n = 1, 2, 3, 4 or 6 and conjectured that Gn(Q) is not a group for any other values of n. This conjecture was confirmed for n = 2r3s or n = pr, where p ≥ 5 is a prime number such that h(Q(ζ p)) is not divisible by p. Inthis paper we confirm the conjecture for some n, where n is not of the above forms, more precisely, for n = 15, 21, 33, 35, 60 or 105.

  14. Stellar & Planetary Parameters for K2's M dwarf Systems

    Science.gov (United States)

    Martinez, Arturo Omar; Crossfield, Ian; Schlieder, Joshua E.; Petigura, Erik; Aller, Kimberly Mei; Lepine, Sebastien; Beichman, Charles A.; Howard, Andrew; Werner, Michael W.

    2016-01-01

    The ongoing K2 mission uses photometry in order to find planets around stars of various types. M dwarfs are of high interests since they have been shown to host more planets than any other main sequence stars and transiting planets around M dwarfs are easier to find. In this poster, we present stellar parameters from M dwarfs hosting transiting planet candidates discovered by our team. Spectra of various bright M dwarfs and K2 objects were obtained in the J, H, and K bands (0.95 microns to 2.52 microns) at R ~ 1000. We measure equivalent widths of spectra features to obtain stellar radii and effective temperatures. Since planet radii and equilibrium temperatures depend on calculating the parameters of its host stars, understanding the nature of the hosts stars improves the precision with which we can measure these K2 objects of interest.

  15. Kepler K2 Precision Lightcurve Observations of Pluto: Preliminary Results

    Science.gov (United States)

    Lisse, Casey M.; Benecchi, Susan D.; Binzel, Richard; Schwamb, Megan Elizabeth; New Horizons Science Team

    2016-10-01

    Pluto is a key object in the third zone of our Solar System and provides important insight into formation and collisional processes that were at work in the early solar system. In July 2015 the New Horizons spacecraft successfully obtained high resolution fly-by clear filter imaging observations of the Pluto system. We report on our continued monitoring of the Pluto system from October-December 2015 using the Kepler spacecraft's imaging photometer during Campaign 7 of the K2 extended mission (Howell et al. 2014). We obtained an unprecedented 83-day nearly continuous lightcurve with measurements every 30 minutes using Kepler's long cadence sampling. The result was 3,980 discrete, unresolved measurements of the combined Pluto system. The 3-month baseline allowed us to sample rotational variations and solar phase angles ranging from 1.1°-1.7° during the period of observation. This dataset is a key baseline for advancing the study of Pluto's actively evolving surface-atmosphere interaction as revealed by the surface geomorphology discovered by New Horizons. Our challenge is to gain an understanding of the ways in which Pluto's surface can be evolving as it recedes from the Sun, and of the influence of Pluto and Charon on each other. In this paper, we present our preliminary results from our K2 dataset. We describe the challenges in reducing the K2 lightcurve data for a target moving across the K2 FOV, and our progress in understanding the lightcurve's variability, which in our current reduction is due to a combination of systematics in the K2 dataset and inherent characteristics of the Pluto system's rotation and changing orbital geometry wrt the Sun and the Earth.This work was supported by NASA's K2 and New Horizons missions.

  16. The Asymmetric CFT Landscape in D=4,6,8 with Extended Supersymmetry

    CERN Document Server

    Blumenhagen, Ralph; Plauschinn, Erik

    2016-01-01

    We study asymmetric simple-current extensions of Gepner models in dimensions $D=4,6,8$ with at least eight supercharges in the right-moving sector. The models obtained in an extensive stochastic computer search belong to a small number of different classes. These classes can be categorized as dimensional reductions, asymmetric orbifolds with $(-1)^{F_L}$, extra gauge enhancement and as coming from the super Higgs-effect. Models in the latter class are particularly interesting, as they may correspond to non-geometric flux compactifications.

  17. Synthesis of 6,8-dichloroquinolones utilizing new method and evaluation of their antibacterial activities

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Several 6,8-dichloroquinolone analogues were synthesized from the key intermediate compound of 2,3,4,5-tetrachlorobenzene carbonyl chloride, which was obtained from the starting material of tetrachlorophthalic anhydride. Their in vitro antibacterial activities were evaluated. As a result of this study, compounds 21c and 21d were twofold more potent than ciprofloxacin (CPFX)and norfloxacin (NFLX) against Staphylococcus aureus-9, and with the same potent as CPFX and NFLX while against Escherichia coli-2, but were less potent than references in against Pseudomonas aeruginosa-17.

  18. Nuclear Halo-Like Phenomena of 6,8He and Nuclear Short Range Correlation

    Institute of Scientific and Technical Information of China (English)

    ZHOU Li-Juan; WU Qing; HE Xiao-Rong; MA Wei-Xing

    2004-01-01

    Based on the nuclear short range correlation in a halo-like nucleus, theoretical analysis of the experimental cross sections for small-angle elastic p-4,6,8He scattering at the energy of about 0.7 GeV has been performed in the framework of Glauber multiple scattering theory. Our theoretical calculations reproduce the corresponding experimental data quite successfully. These good agreements confirm that the nuclear halo-like phenomena may originate from the short range correlation between nucleons in a halo-like nucleus.

  19. Nuclear Halo-Like Phenomena of 6,8 He and Nuclear Short Range Correlation

    Institute of Scientific and Technical Information of China (English)

    ZHOULi-Juan; WUQinq; HEXiao-Rong; MAWei-Xing

    2004-01-01

    Based on the nuclear short range correlation in a halo-like nucleus, theoretical analysis of the experimental cross sections for small-angle elastic p-4,6,8 He scattering at the energy of about 0.7 GeV has been performed in the framework of Glauber multiple scattering theory. Our theoretical calculations reproduce the corresponding experimental data quite successfully. These good agreements confirm that the nuclear halo-like phenomena may originate from the short range correlation between nucleons in a halo-like nucleus.

  20. New Results from Super-K and K2K

    CERN Document Server

    Wilkes, R J

    2002-01-01

    This paper summarizes recent (as of SSI-02, in some cases updated in November, 2002) results from the Super-Kamiokande and K2K experiments. The interpretation of Super-Kamiokande results on atmospheric and solar neutrinos provides strong evidence for neutrino oscillations, hence non-zero neutrino mass. While statistics are still limited, K2K data are consistent with Super-Kamiokande results on neutrino oscillations. The effort to reconstruct Super-Kamiokande following a cascade of phototube implosions in November, 2001 is described. Plans for the future are also discussed.

  1. Taking the Galactic Exoplanet Census with K2

    Science.gov (United States)

    Christiansen, Jessie; CHAI (California/Hawaii/Arizona/Indiana) K2 Follow-up Consortium

    2016-06-01

    The NASA Kepler mission was designed and executed with the goal of measuring planet occurrence rates. The stellar sample, the science pipeline, and the planet candidate sample have all been chosen and characterised with an eye to generating uniform, robust statistical measurements. The subsequent K2 mission, however, has been much more open to all science goals, and subsequently the target selection, planet candidate generation and catalogue assembly have been substantially more ad hoc. Here we discuss the pathway forward to using the Galactic latitude coverage of K2 to begin the Galactic exoplanet census that will be continued by the NASA TESS mission.

  2. K2-30 b and K2-34 b: Two inflated hot Jupiters around solar-type stars

    Science.gov (United States)

    Lillo-Box, J.; Demangeon, O.; Santerne, A.; Barros, S. C. C.; Barrado, D.; Hébrard, G.; Osborn, H. P.; Armstrong, D. J.; Almenara, J.-M.; Boisse, I.; Bouchy, F.; Brown, D. J. A.; Courcol, B.; Deleuil, M.; Delgado Mena, E.; Díaz, R. F.; Kirk, J.; Lam, K. W. F.; McCormac, J.; Pollacco, D.; Rajpurohit, A.; Rey, J.; Santos, N. C.; Sousa, S. G.; Tsantaki, M.; Wilson, P. A.

    2016-10-01

    We report the discovery of the two hot Jupiters K2-30 b and K2-34 b. The two planets were detected during campaigns 4 and 5 of the extension of the Kepler mission, K2; they transit their main-sequence stars with periods of ~4.099 and ~2.996 days. Subsequent ground-based radial velocity follow-up with SOPHIE, HARPS-N, and CAFE established the planetary nature of the transiting objects. We analyzed the transit signal, radial velocity, and spectral energy distributions of the two systems to characterize their properties. Both planets (K2-30 b and K2-34 b) are bloated hot Jupiters (1.20 RJup and 1.22 RJup) around relatively bright (V = 13.5 and V = 11.5) slow rotating main-sequence (G8 and F9) stars. Thus, these systems are good candidates for detecting the Rossiter-MacLaughlin effect in order to measure their obliquity and for atmospheric studies. Full Tables 1 and 2 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/594/A50

  3. CLASH: A Census of Magnified Star-Forming Galaxies at z ~ 6-8

    CERN Document Server

    Bradley, L D; Coe, D; Bouwens, R; Postman, M; Balestra, I; Grillo, C; Monna, A; Rosati, P; Seitz, S; Host, O; Lemze, D; Moustakas, J; Moustakas, L A; Shu, X; Zheng, W; Broadhurst, T; Carrasco, M; Jouvel, S; Koekemoer, A; Medezinski, E; Meneghetti, M; Nonino, M; Smit, R; Umetsu, K; Bartelmann, M; Benitez, N; Donahue, M; Ford, H; Infante, L; Jimenez-Teja, Y; Kelson, D; Lahav, O; Maoz, D; Melchior, P; Merten, J; Molino, A

    2013-01-01

    We utilize 16-band Hubble Space Telescope (HST) observations of 18 lensing clusters obtained as part of the Cluster Lensing And Supernova survey with Hubble (CLASH) Multi-Cycle Treasury program to search for z~6-8 galaxies. We report the discovery of 206, 45, and 13 Lyman-break galaxy (LBG) candidates at z~6, z~7, and z~8, respectively, identified from purely photometric redshift selections. This large sample, representing nearly an order of magnitude increase in the number of magnified star-forming galaxies at z~6-8 presented to date, is unique in that we have observations in four WFC3/UVIS UV, seven ACS/WFC optical and all five WFC3/IR broad-band filters, which enable very accurate photometric redshift selections. We construct detailed lensing models for all 18 clusters (although some are preliminary) to estimate object magnifications and to identify two new multiply-lensed z >~ 6 candidates. The median magnifications for these 18 clusters are 4, 4, and 5 for the z~6, z~7, and z~8 samples, respectively, ove...

  4. An Investigation of Attitudes of 6-8th Graders Towards Universal Values

    Directory of Open Access Journals (Sweden)

    Ender DURUALP

    2012-10-01

    Full Text Available This study aims to describe attitudes of 6-8th graders towards universal values and examine the impact of their age, gender, grade level, academic performance, parental level of education, and family income on their attitudes towards universal values. The population consisted of 6-8th graders being taught in primary schools in Çankırı, Turkey. The sample consisted of 361 students (203 girls, 158 boys randomly selected from Çankırı İsmet İnönü Elementary School located in Çankırı which attracts the highest number of students from each level of socioeconomic status. The sociodemographic data of children and their parents were collected through a “General Information Form”, and the data related to attitudes towards universal values were obtained by the “Attitude Towards Universal Values Scale” developed by Demir and Koç (2009. Data were analyzed through Kolmogorov-Smirnov, Mann-Whitney U, Kruskal-Wallis H tests, and Cronbach Alpha (α reliability coefficient. Results showed that girls (p>0.05, 8th graders, academically-talented children, those whose parents are university graduates, and those with a family income of minimum wage or more have more positive attitudes towards universal values (p<0.05.

  5. The exposition of John 17:6-8: An exegetical exercise

    Directory of Open Access Journals (Sweden)

    D.G. van der Merwe

    2003-11-01

    Full Text Available This essay is an exegesis of Jn 17:6-8 aimed at gaining an understanding of what the Fourth Evangelist tries to emphasize and to communicate concerning the character and success of Jesus This essay is an exegesis of Jn 17:6-8 aimed at gaining an understanding of what the Fourth Evangelist tries to emphasize and to communicate concerning the character and success of Jesus’ earthly ministry. Firstly, a discourse analysis is conducted to point out the linguistic symmetric parallelism through which the Evangelist (1 emphasizes the success of Jesus’ ministry, (2 structures the principal components of Jesus’ ministry and the response of his disciples and (3 tries to explain the meaning of these components. Secondly, a theological exposition of these principal components is conducted, in respect of (1 Revelation: … (2 Obedience /Acceptance: … and (3 Faith: … ( earthly ministry. Firstly, a discourse analysis is conducted to point out the linguistic symmetric parallelism through which the Evangelist (1 emphasizes the success of Jesus’ ministry, (2 structures the principal components of Jesus’ ministry and the response of his disciples and (3 tries to explain the meaning of these components. Secondly, a theological exposition of these principal components is conducted, in respect of (1 Revelation: … (2 Obedience / Acceptance: … and (3 Faith: … (

  6. The role of menaquinones (vitamin K2) in human health

    Science.gov (United States)

    International Life Sciences Institute (ILSI) Europe convened experts in vitamin K selected from academia and industry to review the need for specific dietary reference values (DRVs) for vitamin K2, also known as menaquinones. This review describes the literature based on the following items required...

  7. Beyond the Kepler/K2 bright limit

    DEFF Research Database (Denmark)

    White, T. R.; Pope, B. J. S.; Antoci, V.

    2017-01-01

    The most powerful tests of stellar models come from the brightest stars in the sky, for which complementary techniques, such as astrometry, asteroseismology, spectroscopy and interferometry, can be combined. The K2 mission is providing a unique opportunity to obtain high-precision photometric tim...

  8. Rerefinement of K-2[TiF6

    NARCIS (Netherlands)

    Gobel, O

    2000-01-01

    Crystals of dipotassium hexafluorotitanate(IV), K-2[TiF6], were grown from aqueous solution. The crystal structure was refined with anisotropic displacement parameters. Ti4+ is octahedrally coordinated by F- (point group (3) over bar m), and K+ is 12-coordinate (point group 3m). The dispersion of bi

  9. Transiting exoplanet candidates from K2 Campaigns 5 and 6

    Science.gov (United States)

    Pope, Benjamin J. S.; Parviainen, Hannu; Aigrain, Suzanne

    2016-10-01

    We introduce a new transit search and vetting pipeline for observations from the K2 mission, and present the candidate transiting planets identified by this pipeline out of the targets in Campaigns 5 and 6. Our pipeline uses the Gaussian process-based K2SC code to correct for the K2 pointing systematics and simultaneously model stellar variability. The systematics-corrected, variability-detrended light curves are searched for transits with the box-least-squares method, and a period-dependent detection threshold is used to generate a preliminary candidate list. Two or three individuals vet each candidate manually to produce the final candidate list, using a set of automatically generated transit fits and assorted diagnostic tests to inform the vetting. We detect 145 single-planet system candidates and 5 multi-planet systems, independently recovering the previously published hot Jupiters EPIC 212110888b, WASP-55b (EPIC 212300977b) and Qatar-2b (EPIC 212756297b). We also report the outcome of reconnaissance spectroscopy carried out for all candidates with Kepler magnitude Kp ≤ 13, identifying 12 targets as likely false positives. We compare our results to those of other K2 transit search pipelines, noting that ours performs particularly well for variable and/or active stars, but that the results are very similar overall. All the light curves and code used in the transit search and vetting process are publicly available, as are the follow-up spectra.

  10. Probing TRAPPIST-1-like Systems with K2

    Science.gov (United States)

    Demory, Brice-Olivier; Queloz, Didier; Alibert, Yann; Gillen, Ed; Gillon, Michael

    2016-07-01

    The search for small planets orbiting late M dwarfs holds the promise of detecting Earth-size planets for which their atmospheres could be characterized within the next decade. The recent discovery of TRAPPIST-1 entertains hope that these systems are common around hosts located at the bottom of the main sequence. In this Letter, we investigate the ability of the repurposed Kepler mission (K2) to probe planetary systems similar to TRAPPIST-1. We perform a consistent data analysis of 189 spectroscopically confirmed M5.5 to M9 late M dwarfs from Campaigns 1-6 to search for planet candidates and inject transit signals with properties matching TRAPPIST-1b and c. We find no transiting planet candidates across our K2 sample. Our injection tests show that K2 is able to recover both TRAPPIST-1 planets for 10% of the sample only, mainly because of the inefficient throughput at red wavelengths resulting in Poisson-limited performance for these targets. Increasing injected planetary radii to match GJ 1214b’s size yields a recovery rate of 70%. The strength of K2 is its ability to probe a large number of cool hosts across the different campaigns, out of which the recovery rate of 10% may turn into bona fide detections of TRAPPIST-1-like systems within the next two years.

  11. The K2 Mission: Characterization and Early results

    CERN Document Server

    Howell, Steve B; Haas, Michael; Still, Martin; Barclay, Thomas; Mullally, Fergal; Troeltzsch, John; Aigrain, Suzanne; Bryson, Stephen T; Caldwell, Doug; Chaplin, William J; Cochran, William D; Huber, Daniel; Marcy, Geoffrey W; Miglio, Andrea; Najita, Joan R; Smith, Marcie; Twicken, J D; Fortney, Jonathan J

    2014-01-01

    The K2 mission will make use of the Kepler spacecraft and its assets to expand upon Kepler's groundbreaking discoveries in the fields of exoplanets and astrophysics through new and exciting observations. K2 will use an innovative way of operating the spacecraft to observe target fields along the ecliptic for the next 2-3 years. Early science commissioning observations have shown an estimated photometric precision near 400 ppm in a single 30 minute observation, and a 6-hour photometric precision of 80 ppm (both at V=12). The K2 mission offers simultaneous observation of thousands of objects at a precision far better than is achievable from the ground. Ecliptic fields will be observed for approximately 75-days enabling a unique exoplanet survey which fills the gaps in duration and sensitivity between the Kepler and TESS missions, and offers pre-launch exoplanet target identification for JWST transit spectroscopy. Astrophysics observations with K2 will include studies of young open clusters, bright stars, galaxi...

  12. Associations among different orofacial dysfunctions in 6-8 year olds.

    Science.gov (United States)

    Laine, M T; Pahkala, R H; Jaroma, S M; Qvarnström, M J

    1992-11-01

    Associations among several orofacial dysfunctions such as articulatory speech disorders, craniomandibular disorders (CMD) and problems in coordinating the orofacial muscles were examined in two groups of Finnish first-graders, i.e. children with and without speech disorders. In the whole sample of 287 subjects the mean age was 7.5 yr. A speech therapist diagnosed articulatory speech disorders and a phoniatrician examined the morphology and function of the articulators. Signs and symptoms of CMD, capacity for mandibular movement, and prevalence of occlusal interferences were examined by a dentist. Deviations in motor skills, but not in morphology of the articulators, were associated with speech disorders. The findings also suggested that capacity for mandibular movement, deviation of the jaw during maximal mouth opening and occlusal interferences were related to certain speech disorders among these 6-8 yr olds. Different orofacial dysfunctions appear to be associated with each other during growth.

  13. An unusual binodal (6,8)-connected 3D supramolecular network with twofold self-penetration

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    A dicarboxylate ligand,5-carboxyl-1-carboxymethyl-2-oxidopyridinium (H2L),was utilized to form four complexes with the general formula [M(HL)2(H2O)]·2H2O,M = CuII (1),ZnII (2),MnII (3),CdII (4).The crystals were isomorphous,belonging to the monoclinic C2/c space group.They were constructed from 1D chains and further linked by hydrogen bonds into a novel binodal (6,8)-connected 3D supramolecular network with twofold self-penetration.Photoluminescence studies revealed that complexes 2-4 displayed intense structure-related fluorescent emission bands.

  14. K2's First Five-Planet System

    Science.gov (United States)

    Kohler, Susanna

    2016-08-01

    Whats the latest from the Kepler K2 mission? K2 has found its first planetary system containing more than three planets an exciting five-planet system located ~380 light-years from Earth!Opportunities From K2Raw K2 light curve (blue, top) and systematic corrected light curve (orange, bottom) for HIP 41378. The three deepest transits are single transits from the three outermost planet candidates. [Vanderburg et al. 2016]The original Kepler mission was enormously successful, discovering thousands of planet candidates. But one side effect of Keplers original observing technique, in which it studied the same field for four years, is that it was very good at detecting extremely faint systems systems that were often too faint to be followed up with other techniques.After Keplers mechanical failure in 2013, the K2 mission was launched, in which the spacecraft uses solar pressure to stabilize it long enough to perform an 80-day searches of each region it examines. Over the course of the K2 mission, Kepler could potentially survey up to 20 times the sky area of the original mission, providing ample opportunity to find planetary systems around bright stars. These stars may be bright enough to be followed up with other techniques.Multi-Planet SystemsTheres a catch to the 80-day observing program: the K2 mission is less likely to detect multiple planets orbiting the same star, due to the short time spent observing the system. While the original Kepler mission detected systems with up to seven planets, K2 had yet to detect systems with more than three candidates until now.Led by Andrew Vanderburg (NSF Graduate Research Fellow at the Harvard-Smithsonian Center for Astrophysics), a team of scientists recentlyanalyzed K2 observations ofthe bright star HIP 41378. Theteamfound that this F-type star hosts five potential planetary candidates!Phase-folded light curve for each of the five transiting planets in the HIP 41378 system. The outermost planet (bottom panel) may provide an

  15. On the torsion in K2 of a field

    Institute of Scientific and Technical Information of China (English)

    XU KeJian; LIU Min

    2008-01-01

    For a field F, let Gn(F)={{a,Φn(a)}∈K2(F)|a,Φn(a)∈F*}, where Φn(x) is the n-th cyclotomic polynomial. At first, by using Faltings'theorem on Mordell conjecture it is proved that if F is a number field and if n≠4,8, 12 is a positive integer having a square factor then Gn(F) is not a subgroup of K2(F), and then by using the results of Manin, Grauert, Samuel and Li on Mordell conjecture theorem for function fields, a similar result is established for function fields over an algebraically closed field.

  16. A HARPS view on K2-3

    CERN Document Server

    Almenara, J M; Bonfils, X; Forveille, T; Santerne, A; Albrecht, S; Barros, S C C; Bouchy, F; Delfosse, X; Demangeon, O; Díaz, R F; Hébrard, G; Mayor, M; Neves, V; Rojo, P; Santos, N C; Wünsche, A

    2015-01-01

    K2 space observations recently found that three super-Earths transit the nearby M dwarf K2-3. The apparent brightness and the small physical radius of their host star rank these planets amongst the most favourable for follow-up characterisations. The outer planet orbits close to the inner edge of the habitable zone and might become one of the first exoplanets searched for biomarkers using transmission spectroscopy. We used the HARPS velocimeter to measure the mass of the planets. The mass of planet $b$ is $8.4\\pm2.1$ M$_\\oplus$, while our determination of those planets $c$ and $d$ are affected by the stellar activity. With a density of $4.32^{+2.0}_{-0.76}$ $\\mathrm{g\\;cm^{-3}}$, planet $b$ is probably mostly rocky, but it could contain up to 50% water.

  17. Probing TRAPPIST-1-like Systems with K2

    OpenAIRE

    Demory, Brice-Olivier; Queloz, Didier; Alibert, Yann; Gillen, Ed; Gillon, Michaël

    2016-01-01

    The search for small planets orbiting late M dwarfs holds the promise of detecting Earth-size planets for which their atmospheres could be characterized within the next decade. The recent discovery of TRAPPIST-1 entertains hope that these systems are common around hosts located at the bottom of the main sequence. In this Letter, we investigate the ability of the repurposed Kepler mission (K2) to probe planetary systems similar to TRAPPIST-1. We perform a consistent data analysis of 189 spectr...

  18. Mathematics Teachers’ Opinions about New Sub Learning Domains in Elementary Mathematics (6-8 Curriculum

    Directory of Open Access Journals (Sweden)

    Kürşat YENİLMEZ

    2013-06-01

    Full Text Available Purpose: There are mathematical behaviors in all levels from the preschool education to higher education programs. These behaviors are in mathematics curriculum as objectives. Elementary Mathematics (6-8th grades curriculum was developed in 2005 at last and applied gradually from the 6th grade in 2006-2007 academic year. Thematic approach was considered in regulating context in new mathematics curriculum and determined learning domains and sub learning domains. Some subjects were taken out and some new subjects were added in developing program studies. Patterns and relations in integers, translation, tessellations, structural drawings, transformation geometry, fractals, geometric movements, histogram, kinds of probability, standard deviation, combination, perspective drawings, intersections of objects, polyhedral objects, symmetries of geometric objects are some new subjects in mathematics (6-8th grades curriculum. Patterns and relations in integers and special number patterns are in Patterns and Relations in Algebra learning domain, translation, reflection, rotation, geometric movements and symmetries of geometric objects, tessellations and fractal, structural drawings, intersections of objects and polyhedral objects are in Geometry learning domain, histogram, kinds of probability, standard deviation, combination are in Probability and Statistics learning domain. The purpose of this study was to determine mathematics teachers’ opinions and qualifications about new sub learning domains in elementary mathematics (6-8th grades curriculum. The descriptive survey method was used in the study. The work group of the study consists of 27 mathematics teachers from primary schools in Tekirdağ. Data were collected by a questionnaire which has been developed by the researchers. The questionnaire has 9 open-ended and 17 close-ended questions. Open-ended questions were used to determine mathematics teachers’ views about new sub learning domains were

  19. Planet Hunters 2 in the K2 Era

    Science.gov (United States)

    Schwamb, Megan E.; Fischer, Debra; Boyajian, Tabetha S.; Giguere, Matthew J.; Ishikawa, Sascha; Lintott, Chris; Lynn, Stuart; Schmitt, Joseph; Snyder, Chris; Wang, Ji; Barclay, Thomas

    2015-01-01

    Planet Hunters (http://www.planethunters.org) is an online citizen science project enlisting hundreds of thousands of people to search for planet transits in the publicly released Kepler data. Volunteers mark the locations of visible transits in a web interface, with multiple independent classifiers reviewing a randomly selected ~30-day light curve segment. In September 2014, Planet Hunters entered a new phase. The project was relaunched with a brand new online classification interface and discussion tool built using the Zooniverse's (http://www.zooniverse.org) latest technology and web platform. The website has been optimized for the rapid discovery and identification of planet candidates in the light curves from K2, the two-wheeled ecliptic plane Kepler mission. We will give an overview of the new Planet Hunters classification interface and Round 2 review system in context of the K2 data. We will present the first results from the Planet Hunters 2 search of K2 Campaigns 0 and 1 including a summary of new planet candidates.

  20. Transiting exoplanet candidates from K2 Campaigns 5 and 6

    CERN Document Server

    Pope, Benjamin J S; Aigrain, Suzanne

    2016-01-01

    We introduce a new transit search and vetting pipeline for observations from the K2 mission, and present the candidate transiting planets identified by this pipeline out of the targets in Campaigns 5 and 6. Our pipeline uses the Gaussian Process-based K2SC code to correct for the K2 pointing systematics and simultaneously model stellar variability. The systematics-corrected, variability-detrended light curves are searched for transits with the Box Least Squares method, and a period-dependent detection threshold is used to generate a preliminary candidate list. Two or three individuals vet each candidate manually to produce the final candidate list, using a set of automatically-generated transit fits and assorted diagnostic tests to inform the vetting. We detect 147 single-planet system candidates and 5 multi-planet systems, independently recovering the previously-published hot~Jupiters EPIC 212110888b, WASP-55b (EPIC 212300977b) and Qatar-2b (EPIC 212756297b). We also report the outcome of reconnaissance spec...

  1. Doppler Monitoring of five K2 Transiting Planetary Systems

    CERN Document Server

    Dai, Fei; Albrecht, Simon; Arriagada, Pamela; Bieryla, Allyson; Butler, R Paul; Crane, Jeffrey D; Hirano, Teriyuki; Johnson, John Asher; Kiilerich, Amanda; Latham, David W; Narita, Norio; Nowak, Grzegorz; Palle, Enric; Ribas, Ignasi; Rogers, Leslie A; Sanchis-Ojeda, Roberto; Shectman, Stephen A; Teske, Johanna K; Thompson, Ian B; Van Eylen, Vincent; Vanderburg, Andrew; Wittenmyer, Robert A; Yu, Liang

    2016-01-01

    In an effort to measure the masses of planets discovered by the NASA {\\it K2} mission, we have conducted precise Doppler observations of five stars with transiting planets. We present the results of a joint analysis of these new data and previously published Doppler data. The first star, an M dwarf known as K2-3 or EPIC~201367065, has three transiting planets ("b", with radius $2.1~R_{\\oplus}$; "c", $1.7~R_{\\oplus}$; and "d", $1.5~R_{\\oplus}$). Our analysis leads to the mass constraints: $M_{b}=8.1^{+2.0}_{-1.9}~M_{\\oplus}$ and $M_{c}$ < $ 4.2~M_{\\oplus}$~(95\\%~conf.). The mass of planet d is poorly constrained because its orbital period is close to the stellar rotation period, making it difficult to disentangle the planetary signal from spurious Doppler shifts due to stellar activity. The second star, a G dwarf known as K2-19 or EPIC~201505350, has two planets ("b", $7.7~R_{\\oplus}$; and "c", $4.9~R_{\\oplus}$) in a 3:2 mean-motion resonance, as well as a shorter-period planet ("d", $1.1~R_{\\oplus}$). We f...

  2. Probing TRAPPIST-1-like systems with K2

    CERN Document Server

    Demory, Brice-Olivier; Alibert, Yann; Gillen, Ed; Gillon, Michael

    2016-01-01

    The search for small planets orbiting late M dwarfs holds the promise of detecting Earth-size planets for which their atmospheres could be characterised within the next decade. The recent discovery of TRAPPIST-1 entertains hope that these systems are common around hosts located at the bottom of the main sequence. In this Letter, we investigate the ability of the repurposed Kepler mission (K2) to probe planetary systems similar to TRAPPIST-1. We perform a consistent data analysis of 189 spectroscopically confirmed M5.5 to M9 late M dwarfs from campaigns 1-6 to search for planet candidates and inject transit signals with properties matching TRAPPIST-1b and c. We find no transiting planet candidates across our K2 sample. Our injection tests show that K2 is able to recover both TRAPPIST-1 planets for 10% of the sample only, mainly because of the inefficient throughput at red wavelengths resulting in Poisson-limited performance for these targets. Increasing injected planetary radii to match GJ1214b's size yields a...

  3. Systematics-insensitive periodic signal search with K2

    CERN Document Server

    Angus, Ruth; Johnson, John A

    2015-01-01

    From pulsating stars to transiting exoplanets, the search for periodic signals in K2 data, Kepler's 2-wheeled extension, is relevant to a long list of scientific goals. Systematics affecting K2 light curves due to the decreased spacecraft pointing precision inhibit the easy extraction of periodic signals from the data. We here develop a method for producing periodograms of K2 light curves that are insensitive to pointing-induced systematics; the Systematics-Insensitive Periodogram (SIP). Traditional sine-fitting periodograms use a generative model to find the frequency of a sinusoid that best describes the data. We extend this principle by including systematic trends, based on a set of 'Eigen light curves', following Foreman-Mackey et al. (2015), in our generative model as well as a sum of sine and cosine functions over a grid of frequencies. Using this method we are able to produce periodograms with vastly reduced systematic features. The quality of the resulting periodograms are such that we can recover aco...

  4. EVEREST: Pixel Level Decorrelation of K2 Light Curves

    Science.gov (United States)

    Luger, Rodrigo; Agol, Eric; Kruse, Ethan; Barnes, Rory; Becker, Andrew; Foreman-Mackey, Daniel; Deming, Drake

    2016-10-01

    We present EPIC Variability Extraction and Removal for Exoplanet Science Targets (EVEREST), an open-source pipeline for removing instrumental noise from K2 light curves. EVEREST employs a variant of pixel level decorrelation to remove systematics introduced by the spacecraft’s pointing error and a Gaussian process to capture astrophysical variability. We apply EVEREST to all K2 targets in campaigns 0-7, yielding light curves with precision comparable to that of the original Kepler mission for stars brighter than {K}p≈ 13, and within a factor of two of the Kepler precision for fainter targets. We perform cross-validation and transit injection and recovery tests to validate the pipeline, and compare our light curves to the other de-trended light curves available for download at the MAST High Level Science Products archive. We find that EVEREST achieves the highest average precision of any of these pipelines for unsaturated K2 stars. The improved precision of these light curves will aid in exoplanet detection and characterization, investigations of stellar variability, asteroseismology, and other photometric studies. The EVEREST pipeline can also easily be applied to future surveys, such as the TESS mission, to correct for instrumental systematics and enable the detection of low signal-to-noise transiting exoplanets. The EVEREST light curves and the source code used to generate them are freely available online.

  5. EVEREST: Pixel Level Decorrelation of K2 Light curves

    CERN Document Server

    Luger, Rodrigo; Kruse, Ethan; Barnes, Rory; Becker, Andrew; Foreman-Mackey, Daniel; Deming, Drake

    2016-01-01

    We present EVEREST, an open-source pipeline for removing instrumental noise from K2 light curves. EVEREST employs a variant of pixel level decorrelation (PLD) to remove systematics introduced by the spacecraft's pointing error and a Gaussian process (GP) to capture astrophysical variability. We apply EVEREST to all K2 targets in campaigns 0-7, yielding light curves with precision comparable to that of the original Kepler mission for stars brighter than $K_p \\approx 13$, and within a factor of two of the Kepler precision for fainter targets. We perform cross-validation and transit injection and recovery tests to validate the pipeline, and compare our light curves to the other de-trended light curves available for download at the MAST High Level Science Products archive. We find that EVEREST achieves the highest average precision of any of these pipelines for unsaturated K2 stars. The improved precision of these light curves will aid in exoplanet detection and characterization, investigations of stellar variabi...

  6. The Compatibility of Developed Mathematics Textbooks' Content in Saudi Arabia (Grades 6-8) with NCTM Standards

    Science.gov (United States)

    Alshehri, Mohammed Ali; Ali, Hassan Shawki

    2016-01-01

    This study aimed to investigate the compatibility of developed mathematics textbooks' content (grades 6-8) in Saudi Arabia with NCTM standards in the areas of: number and operations, algebra, geometry, measurement, data analysis and probability. To achieve that goal, a list of (NCTM) standards for grades (6-8) were translated to Arabic language,…

  7. Photometry of Main Belt and Trojan asteroids with K2

    Science.gov (United States)

    Szabó, Gyula; Kiss, Csaba; Pal, Andras; Szabo, Robert

    2016-10-01

    Due to the failure of the second reaction wheel, a new mission was conceived for the otherwise healthy Kepler space telescope. In the course of the K2 Mission, the telescope is staring at the plane of the Ecliptic, hence thousands of Solar System bodies cross the K2 fields, usually causing extra noise in the highly accurate photometric data.We could measure the first continuous asteroid light curves, covering several days wthout interruption, that has been unprecedented to date. We studied the K2 superstamps covering the M35 and Neptune/Nereid fields observed in the long cadence (29.4-min sampling) mode. Asteroid light curves are generated by applying elongated apertures. We investigated the photometric precision that the K2 Mission can deliver on moving Solar System bodies, and determined the first uninterrupted optical light curves of main-belt and Trojan asteroids. We use thed Lomb-Scargle method to find periodicities due to rotation.We derived K2 light curves of 924 main-belt asteroids in the M35 field, and 96 in the path of Neptune and Nereid. Due to the faintness of the asteroids and the high density of stars in the M35 field, 4.0% of the asteroids with at least 12 data points show clear periodicities or trend signalling a long rotational period, as opposed to 15.9% in the less crowded Neptune field. We found that the duty cycle of the observations had to reach ˜ 60% in order to successfully recover rotational periods.The derived period-amplitude diagram is consistent to the known distribution of Main Belt asteroids. For Trojan asteroids, the contribution of our 56 objects with newly determined precise period and amplitude is in the order of all previously known asteroids. The comparison with earth-based determinations showed a previous bias toward short periods and has also proven that asteroid periods >20 hour can be unreliable in a few cases because of daylight time and diurnal calibrations. These biases are avoided from the space. We present an unbiased

  8. Deletion and Mutation of WWOX Exons 6-8 in Human Non-small Cell Lung Cancer

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    To examine the deletion and point mutation of WWOX (WW domain containing oxidoreductase) exons 6-8 in human non-small cell lung cancer and their possible relationship with pathological stages, tumor tissues and the corresponding normal tissues were obtained from 44 Chinese patients who had undergone surgery for non-small cell lung cancer. RNA was extracted from each sample and deletion and mutation of WWOX exons 6-8 were analyzed by RT-PCR and DNA sequencing. Our results showed that 28 of 44 (63.6 %) lung cancer samples showed loss of WWOX exons 6-8 transcript and the deletion was detected in only 3 of 44 (6.8 %) corresponding adjacent normal tissues (P<0.05). The transcript sequencing analyses of the 16 lung cancer samples without transcript loss of WWOX exons 6-8 revealed no difference from the sequence of GenBank. Moreover, the deletion of WWOX exons 6-8 was significantly higher in the smokers when compared with the non-smokers. It is also higher in the men and squamous carcinomas than in women and adenocarcinomas (P<0.05). The deletion, however, was not found to be associated with pathological stages of the tumors. Our study documented a high incidence of deletion of WWOX exons 6-8 in non-small cell lung cancer in Chinese patients and suggested that the frequent loss of WWOX exons 6-8 might play an important role in the tumorigenesis of non-small cell lung cancer in Chinese. WWOX exons 6-8 may serves as a candidate molecular target of smoking carcinogenesis, and point mutation is not a predominant way of alteration of WWOX exons 6-8.

  9. Investigation of the Mitochondrial ATPase 6/8 and tRNALys Genes Mutations in Autism

    Directory of Open Access Journals (Sweden)

    Sepideh Dadgar

    2012-01-01

    Full Text Available Objective: Autism results from developmental factors that affect many or all functional brain systems. Brain is one of tissues which are crucially in need of adenosine triphosphate (ATP. Autism is noticeably affected by mitochondrial dysfunction which impairs energy metabolism. Considering mutations within ATPase 6, ATPase 8 and tRNALys genes, associated with different neural diseases, and the main role of ATPase 6/8 in energy generation, we decided to investigate mutations on these mtDNA-encoded genes to reveal their roles in autism pathogenesis.Materials and Methods: In this experimental study, mutation analysis for the mentioned genes were performed in a cohort of 24 unrelated patients with idiopathic autism by employing amplicon sequencing of mtDNA fragments.Results: In this study, 12 patients (50% showed point mutations that represent a significant correlation between autism and mtDNA variations. Most of the identified substitutions (55.55% were observed on MT-ATP6, altering some conserved amino acids to other ones which could potentially affect ATPase 6 function. Mutations causing amino acid replacement denote involvement of mtDNA genes, especially ATPase 6 in autism pathogenesis.Conclusion: MtDNA mutations in relation with autism could be remarkable to realize an understandable mechanism of pathogenesis in order to achieve therapeutic solutions.

  10. Structural Model of Motor Readiness of Young Gymnasts Aged 6-8

    Directory of Open Access Journals (Sweden)

    О. Худолій

    2015-12-01

    Full Text Available The purpose of the research is to determine the factor structure of the motor readiness of young gymnasts aged 6—8. Research methods. To achieve the tasks set, the research relies on theoretical and empirical methods used: analysis and collation of scientific and methodological literature; modeling, pedagogical observations and experiment, factor analysis. The research recorded the following indicators: the number of repetitions required to teach the exercises; score for the unit-directional movement coordination exercise (test 3; score for the differently directed movement coordination exercise (test 4; error in spatial precision of hand movements (test 9; error in spatial accuracy of leg movements (test 14; error in time accuracy of executing the sitting-to-lying event (test 17; error in time accuracy of five jumps on marks in 5 seconds (test 18; error in evaluation of muscular efforts with visual control (test 24; error in evaluation of muscular efforts without visual control (test 25; vestibular stability, error (test 28; wrist strength; back strength; standing long jump. The participants in the study were 40 gymnasts aged 6-7 and 32 gymnasts aged 7-8. Research results. The young gymnasts aged 6-8 have quite distinct elements that determine the development of their sports skills, namely: learning ability, motor experience, coordination complexity of exercises; relationship between the strength development and the ability to differentiate muscular efforts; movement coordination, movement control and vestibular apparatus stability.

  11. The Minimum Halo Mass for Star Formation at z = 6 - 8

    CERN Document Server

    Finlator, K; Oppenheimer, B D; Davé, R; Zackrisson, E; Livermore, R C; Finkelstein, S L; Thompson, R; Huang, S

    2016-01-01

    Recent analysis of strongly-lensed sources in the Hubble Frontier Fields indicates that the rest-frame UV luminosity function of galaxies at $z=$6--8 rises as a power law down to $M_\\mathrm{UV}=-15$, and possibly as faint as -12.5. We use predictions from a cosmological radiation hydrodynamic simulation to map these luminosities onto physical space, constraining the minimum dark matter halo mass and stellar mass that the Frontier Fields probe. While previously-published theoretical studies have suggested or assumed that early star formation was suppressed in halos less massive than $10^9$--$10^{11} M_\\odot$, we find that recent observations demand vigorous star formation in halos at least as massive as (3.1, 5.6, 10.5)$\\times10^9 M_\\odot$ at $z=(6,7,8)$. Likewise, we find that Frontier Fields observations probe down to stellar masses of (8.1, 18, 32)$\\times10^6 M_\\odot$; that is, they are observing the likely progenitors of analogues to Local Group dwarfs such as Pegasus and M32. Our simulations yield somewha...

  12. Participation in School Food and Nutrition Activities among Grade 6-8 Students in Vancouver.

    Science.gov (United States)

    Stephens, Teya A; Black, Jennifer L; Chapman, Gwen E; Velazquez, Cayley E; Rojas, Alejandro

    2016-09-01

    This study examined student-reported participation in school food and nutrition activities in Vancouver, British Columbia (BC), and whether engagement differed by gender and between elementary and secondary school students. A cross-sectional survey of grade 6-8 public school students (n = 937) from 20 elementary and 6 secondary schools assessed student-reported participation in a range of food and nutrition activities. Statistical analyses included descriptive statistics and multilevel logistic regression to examine associations between participation with gender and school type. Overall, students reported engaging in most of the food and nutrition activities examined in the 2011-2012 school year, including: food preparation (36%), choosing/tasting healthy foods (27%), learning about Canada's Food Guide (CFG) (45%), learning about foods grown in BC (35%), gardening (21%), composting (32%), and recycling (51%). Females were more likely to report recycling and learning about CFG and BC-grown foods (P students were more likely to report activities focused on working with or learning about food/nutrition (P students in food and nutrition experiences, participation in most activities remains relatively low, with few students exposed to multiple activities. Continued advocacy is needed from the dietetics community to improve student engagement in food and nutrition activities.

  13. The minimum halo mass for star formation at z = 6-8

    Science.gov (United States)

    Finlator, Kristian; Prescott, Moire K. M.; Oppenheimer, B. D.; Davé, Romeel; Zackrisson, E.; Livermore, R. C.; Finkelstein, S. L.; Thompson, Robert; Huang, Shuiyao

    2017-01-01

    Recent analysis of strongly lensed sources in the Hubble Frontier Fields indicates that the rest-frame UV luminosity function of galaxies at z = 6-8 rises as a power law down to MUV = -15, and possibly as faint as -12.5. We use predictions from a cosmological radiation hydrodynamic simulation to map these luminosities on to physical space, constraining the minimum dark matter halo mass and stellar mass that the Frontier Fields probe. While previously published theoretical studies have suggested or assumed that early star formation was suppressed in haloes less massive than 109-1011 M⊙, we find that recent observations demand vigorous star formation in haloes at least as massive as (3.1, 5.6, 10.5) × 109 M⊙ at z = (6, 7, 8). Likewise, we find that Frontier Fields observations probe down to stellar masses of (8.1, 18, 32) × 106 M⊙: that is, they are observing the likely progenitors of analogues to Local Group dwarfs such as Pegasus and M32. Our simulations yield somewhat different constraints than two complementary models that have been invoked in similar analyses, emphasizing the need for further observational constraints on the galaxy-halo connection.

  14. Mitochondrial tRNALeu/Lys and ATPase 6/8 gene variations in spinocerebellar ataxias.

    Science.gov (United States)

    Safaei, Sepideh; Houshmand, Massoud; Banoei, Mohammad Mehdi; Panahi, Mehdi Shafa Shariat; Nafisi, Shahriar; Parivar, Kazem; Rostami, Maryam; Shariati, Parvin

    2009-01-01

    The spinocerebellar ataxias (SCA) comprise a heterogeneous group of severe late-onset neurodegenerative diseases that are promoted by the expansion of a tandem-arrayed DNA sequence that modifies the primary structure of the protein. Genomic DNA of 20 patients affected with SCAs was extracted from peripheral blood and screened for deletions in mitochondrial DNA (mtDNA). Sequencing of tRNA(Leu), tRNA(Lys), cytochrome oxidase II, ATPase 6/8 and NADH dehydrogenase I (NDI) genes belonging to mtDNA from patients with SCAs was also carried out to detect the presence of variations. We identified cytosine-adenine-guanine (CAG) trinucleotide repeat expansions in 20 patients. Seven of these patients had at least one nucleotide change in mtDNA. In such cases, 5 nucleotide variations resulted in amino acid changes with two novel variations T8256G and G9010A. SCA patients showed high levels of mtDNA variations in lymphocytes. It can be proposed that the SCA gene proteins (Ataxins) are involved in the complicated intracellular mechanisms that affect cellular organelles and their components, such as the mitochondrial genome. The instability of CAG repeats in polyglutamine diseases such as SCAs and Huntington's disease might be a causative factor in mtDNA variation or possible damage. Copyright 2008 S. Karger AG, Basel.

  15. K2 Warm Jupiters with the LCOGT TECH collaboration

    Science.gov (United States)

    Shporer, Avi; Bayliss, Daniel; Cochran, William D.; Colón, Knicole D.; Dragomir, Diana; Palle, Enric; Potter, Stephen; Siverd, Robert; LCOGT TECH Collaboration

    2016-06-01

    Many transiting gas giant planets on short orbital periods (so called hot Jupiters) have larger radii than theoretically expected. Although several explanations have been proposed, none have completely solved this puzzle. As the number of known transiting planets grew a correlation was identified between gas giant radius and the stellar incident flux. Still, it is not clear whether this correlation is causation. Several questions remain and answering them will characterize in more detail this observed correlation and in turn the process responsible for the inflated radii, such as: Is the lack of inflated warm Jupiters a robust feature? What is the incident flux below which there are no inflated gas giants? How low in incident flux does this correlation stretch? These questions arise since there are only a small number of transiting gas giants with low incident flux, below about 108 erg/s/cm2, corresponding to orbital periods of about 10 days and longer for a Sun-like host star. Discovering and confirming more transiting warm Jupiters is the goal of this project, undertaken by the LCOGT Transiting Exoplanet CHaracterization (TECH) team. We are using K2 as our main source of transiting warm Jupiter candidates, with a few candidates discovered in each K2 campaign. LCOGT telescopes are being used for obtaining additional ground-based transit light curves, which are critical for confirming and refining the K2 transit ephemeris as outliers during ingress or egress of the few transit events observed by K2 can bias the measured ephemeris. Further ground-based follow-up data, including spectroscopy, radial velocities, and high angular resolution imaging, are obtained by facilities directly accessible by LCOGT TECH team members. In addition, once LCOGT’s Network of Robotic Echelle Spectrographs (NRES) are deployed in the near future they will allow obtaining spectroscopy and radial velocities with LCOGT facilities. On top of studying the inflated hot Jupiter conundrum

  16. Results from Super-Kamiokande and K2K

    Indian Academy of Sciences (India)

    M R Vagins

    2003-02-01

    Results from Super-Kamiokande-I’s entire 1496 live days of solar neutrino data are presented, including the absolute flux, energy spectrum, zenith angle (day/night) and seasonal variation. The possibility of MSW and vacuum oscillations is discussed in light of these results. Results from the first 1289 days of Super-K-I’s atmospheric neutrino analysis are also presented, including the evidence for → oscillations, against → sterile oscillations, and the current limits on proton decay. Finally, results based on 5.6 × 1019 protons on target are given for the K2K long-baseline neutrino oscillation experiment.

  17. Grass Valley K2媒体服务器

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Thomson推出Profile存储设备系列Grass Valley K2媒体服务器和媒体客户端系统。支持以IT为中心、文档为基础的播出和传输工作流程,简化了安装和操作过程,实现了以文档为基础的无限制工作流程,并提供更高水准的网络控制,性价比高。

  18. Single Transit Candidates from K2: Detection and Period Estimation

    CERN Document Server

    Osborn, H P; Brown, D J A; McCormac, J; Doyle, A P; Louden, T M; Kirk, J; Spake, J J; Lam, K W F; Walker, S R; Faedi, F; Pollacco, D L

    2015-01-01

    Photometric surveys such as Kepler have the precision to identify exoplanet and eclipsing binary candidates from only a single transit. K2, with its 75d campaign duration, is ideally suited to detect significant numbers of single-eclipsing objects. Here we develop a Bayesian transit-fitting tool ("Namaste: An Mcmc Analysis of Single Transit Exoplanets") to extract orbital information from single transit events. We achieve favourable results testing this technique on known Kepler planets, and apply the technique to 7 candidates identified from a targeted search of K2 campaigns 1, 2 and 3. We find EPIC203311200 to host an excellent exoplanet candidate with a period, assuming zero eccentricity, of $540 ^{+410}_{-230}$ days and a radius of $0.51 \\pm 0.05 R_{Jup}$. We also find six further transit candidates for which more follow-up is required to determine a planetary origin. Such a technique could be used in the future with TESS, PLATO and ground-based photometric surveys such as NGTS, potentially allowing the d...

  19. 1,5-Dichloro-3(2,7),7(2,7)-dinaphthal-ena-2,4,6,8-tetra-oxa-1(2,6),5(2,6)-di(1,3,5-triazina)octa-phane.

    Science.gov (United States)

    Sang, Qiu-Guang; Yang, Jing-Kui

    2011-09-01

    In the macrocyclic title compound, C(26)H(12)Cl(2)N(6)O(4), an O-atom-bridged calix[2]naphthalene-[2]triazine synthesized using a one-pot approach from naphthalene-2,7-diol and cyanuric chloride, the two isolated naphthalene planes and the two triazine-2,6-di-oxy planes adopt a 1,3-alternate configuration, with a dihedral angle of 84.10 (8)° between the naphthalene rings and a dihedral angle of 39.02 (14)° between the triazine rings. In the crystal, weak inter-molecular π-π stacking inter-actions are found between face-to-face naphthalene rings [centroid-centroid distance = 3.662 (7) Å].

  20. 1-(4-Bromo-3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-ylethan-1-one: a precursor for phase-I metabolite of AHTN

    Directory of Open Access Journals (Sweden)

    Paul Kuhlich

    2013-04-01

    Full Text Available The title compound, C18H25BrO, crystallized as a racemate with four independent molecules in the asymmetric unit. In the crystal, three of these four molecules are linked via C—Br...Br—C halogen bonds [Br...Br = 3.662 (2 and 3.652 (2 Å], forming dimers.

  1. Preparation of solid base of K2O/C and transesterification catalyzed by the catalyst%固体碱催化剂(K2 O/C)的制备及其催化酯交换反应

    Institute of Scientific and Technical Information of China (English)

    郭萍梅; 黄凤洪; 赵军英; 郑畅

    2009-01-01

    以活性炭为载体,负载K2CO3后经过煅烧,制得K2O/C固体碱催化剂,通过正交实验,得到催化剂的优化制备条件为:K2CO3与活性炭摩尔比0.04,粒径40目,煅烧温度450℃,煅烧时间3.5h,浸渍时间3h;将其应用于催化棉籽油酯交换制备生物柴油,考察了催化剂的加入量、醇油比、反应温度、反应时间、原料中水分含量等对酯交换反应的影响,得到最佳工艺参数:醇油摩尔比8∶ 1、催化剂加入量4.0%、反应时间1h.在此条件下,K2O/C的催化活性优于传统均相催化剂,重复使用多次仍具有较好的催化效果.

  2. Final report on the safety assessment of PEG-6, -8, and -20 sorbitan beeswax.

    Science.gov (United States)

    Lanigan, R S; Yamarik, T A

    2001-01-01

    Polyethylene Glycol (PEG)-6, -8, and -20 Sorbitan Beeswax are ethoxylated derivatives of Beeswax that function as surfactants in cosmetic formulations. Only PEG-20 Sorbitan Beeswax is currently reported to be used, at concentrations up to 11%. Few data on the PEGs Sorbitan Beeswax ingredients were available. This safety assessment relied upon the available data from previous safety assessments of Beeswax, Synthetic Beeswax, Sorbitan Esters, PEGs, and PEG Sorbitan fatty acid esters, also known as Polysorbates. The ester linkage of PEG Sorbitan fatty acid esters was hydrolyzed after oral administration, and the PEG Sorbitan moiety was poorly absorbed from the gastrointestinal tract. Sorbitan Stearate was hydrolyzed to stearic acid and anhydrides of sorbitol in the rat. PEGs are readily absorbed through damaged skin and are associated with contact dermatitis and systemic toxicity in burn patients. PEGs were not sensitizing to normal skin. PEGs did not cause reproductive toxicity, nor were tested PEGs mutagenic or carcinogenic. Sorbitol was not a reproductive or developmental toxin in multigenerational studies in rats. Neither Beeswax nor Synthetic Beeswax produced significant acute animal toxicity, ocular irritation, skin irritation, or skin sensitization. Polysorbates produced no acute or long-term effects, were generally not irritating or sensitizing, and were noncarcinogenic, although studies did demonstrate enhancement of the activity of chemical carcinogens. Sorbitan fatty acid esters were relatively nontoxic via ingestion, generally were not skin irritants or sensitizers, and were not mutagenic or carcinogenic. Sorbitan Laurate was a cocarcinogen in a mouse skin-painting study. PEG-6 Sorbitan Beeswax delivered via a stomach tube was nontoxic in rats in acute studies. Undiluted PEG-6 Sorbitan Beeswax was nonirritating to the eyes of rabbits and was non-irritating to intact and abraded skin of rabbits. PEG-20 Sorbitan Beeswax was only minimally irritating to

  3. RAVE stars in K2 - I. Improving RAVE red giants spectroscopy using asteroseismology from K2 Campaign 1

    CERN Document Server

    Valentini, M; Davies, G R; Elsworth, Y P; Mosser, B; Lund, M N; Miglio, A; Chaplin, W J; Rodrigues, T; Boeche, C; Steinmetz, M; Matijevic, G; Kordopatis, G; Bland-Hawthorn, J; Munari, U; Bienayme, O; Gibson, B K; Gilmore, G; Grebel, E K; Helmi, A; Kunder, A; McMillan, P; Navarro, J; Parker, Q A; Reid, W; Seabroke, G; Siviero, A; Watson, F; Wise, R M; Zwitter, T

    2016-01-01

    We present a set of 87 RAVE stars with detected solar like oscillations, observed during Campaign 1 of the K2 mission (RAVE K2-C1 sample). This dataset provides a useful benchmark for testing the gravities provided in RAVE Data Release 4 (DR4), and is key for the calibration of the RAVE Data Release 5 (DR5). In the present work, we use two different pipelines, GAUFRE (Valentini et al. 2013) and Sp_Ace (Boeche et al. 2015), to determine atmospheric parameters and abundances by fixing log(g) to the seismic one. Our strategy ensures highly consistent values among all stellar parameters, leading to more accurate chemical abundances. A comparison of the chemical abundances obtained here with and without the use of seismic log(g) information has shown that an underestimated (overestimated) gravity leads to an underestimated (overestimated) elemental abundance (e.g. [Mg/H] is underestimated by ~0.25 dex when the gravity is underestimated by 0.5 dex). We then perform a comparison between the seismic gravities and the...

  4. K2 Variable Catalogue II: Variable Stars and Eclipsing Binaries in K2 Fields 1 and 0

    CERN Document Server

    Armstrong, D J; Lam, K W F; McCormac, J; Walker, S R; Brown, D J A; Osborn, H P; Pollacco, D L; Spake, J

    2015-01-01

    We have created a catalogue of variable stars found from a search of the publicly available K2 mission data from Campaigns 1 and 0. This catalogue provides the identifiers of 8395 variable stars, including 199 candidate eclipsing binaries with periods up to 60d and 3871 periodic or quasi-periodic objects, with periods up to 20d for Field 1 and 15d for Field 0. Lightcurves are extracted and detrended from the available data. These are searched using a combination of algorithmic and human classification, leading to a classifier for each object as an eclipsing binary, sinusoidal periodic, quasi periodic, or aperiodic variable. The source of the variability is not identified, but could arise in the non-eclipsing binary cases from pulsation or stellar activity. Each object is cross-matched against variable star related guest observer proposals to the K2 mission, which specifies the variable type in some cases. The detrended lightcurves are also compared to lightcurves currently publicly available. The resulting ca...

  5. A case of HAPE on K2 and literature review.

    Science.gov (United States)

    Sasao, Gen; Nagai, Asuka; Iwamoto, Tokuzen; Ichiwata, Toshio; Kuwahira, Ichiro

    2010-01-01

    HAPE (High Altitude Pulmonary Edema) is a serious and fatal disease in mountains. Early diagnosis and immediate descent are important for successful treatment. One of the authors (GS), who was healthy and a well trained climber, participated in the expedition to K2 (8611 m) in 2006 and developed HAPE. Under the severe environmental condition, it was difficult to evaluate his condition in its early stage. The earliest symptoms were nonspecific for HAPE as reported in many papers. Neither had he suffered from HAPE on the previous expeditions. These facts probably delayed the diagnosis in spite of its typical onset. This is a rare case report by a medical doctor who suffered from HAPE. The present case may remind the climbers of the difficulties in diagnosing HAPE on a mountain.

  6. A Unique Case of Cardiac Arrest following K2 Abuse

    Directory of Open Access Journals (Sweden)

    Saif Ibrahim

    2014-01-01

    Full Text Available Sudden cardiac death (SCD accounts for up to 450,000 deaths every year in the United States (Zipes et al. (2006. Most cases of sudden cardiac death occur in subjects with no prior history of heart disease (Myerburg et al. (1998. The incidence of sudden death in a general population has been shown to increase contemporaneously with substance abuse (Phillips et al. (1999. The causative association of sudden death with cocaine, methadone, and volatile agents is well established (Adgey et al. (1995 and Isner et al. (1986. We describe a case of out-of-hospital cardiac arrest temporally related to abuse of the synthetic cannabinoid street drug known as K2. To our knowledge, there are no previously documented cases of sudden cardiac death associated with synthetic cannabinoids although they have been linked to myocardial infarction in teenagers despite normal coronary angiography (Mir et al. (2011.

  7. K2 and Herschel/PACS photometry of irregular satellites

    Science.gov (United States)

    Pal, Andras; Kiss, Csaba; Molnar, Laszlo; Mueller, Thomas G.; Sarneczky, Krisztian; Szabo, Robert; Kiss, Laszlo L.; Szabo, Gyula M.

    2016-10-01

    The combination of optical and far-infrared photometric measurements yields an unambiguous method for characterizing the basic physical and surface properties of minor bodies in the Solar System. In principle, an object with a certain visible brightness can either be an object with a small but bright or a large but dim surface. To resolve this issue, conducting thermal emission measurements can also be acquired since both larger and dimmer objects have higher infrared radiations. In addition, the precise modelling of thermal emission should certainly take into account the rotation period of these bodies - otherwise the presence of surface thermal inertia can result in inaccurate conclusions regarding to the physical size and albedo.Since early 2014, Kepler Space Telescope surveys fields close to the Ecliptic in a framework of quarterly campaigns of the K2 initiative. This program makes possible to continuously observe Solar System bodies during this period of 80-90 days and hence provide an uninterrupted photometric series of moving Solar System objects down to the magnitude range of R = 23.5. This instrument hence an ideal observatory now for Solar System studies. Due to the fact that the expected rotational periods of these objects are commensurable to the diurnal characteristics of ground-based observations, such uninterrupted light curves are rather valuable for the accurate determination of rotational characteristics - including the physical rotation period, the amplitude and the confirmation of the presence of double- or multiple peaked features.In this presentation we summarize our results of current K2 and legacy Herschel/PACS observations regarding to some of the irregular satellites of Uranus and Neptune, namely Caliban, Sycorax, Prospero, Setebos and Nereid. By comparing these results with similar kind of observations for trans-Neptunian objects (see Kiss et al., this DPS meeting), one can conclude how the formation and evolution of the outer Solar

  8. Soil radon and electromagnetic anomalies before the Ileia(Greece) M6.8 earthquake

    Science.gov (United States)

    Nikolopoulos, D.; Vogiannis, E.; Louizi, A.; Zisos, A.

    2009-04-01

    Radon (222Rn) is a radioactive gas generated by the decay of the naturally occurring 238U series. It is considered very important from radiological point of view, since it accounts for more than half of the natural exposure of the general public. Radon has been used as trace gas in several studies of Earth, hydrogeology and atmosphere, due to its 3.82-day half-life (which allows migration at long distances) and its alpha decay (which enables low level of detection). It has been accounted in the search of earthquake precursors, volcanic processes, fluid circulation in karstic sources and in the study of natural ventilation of underground cavities. Radon anomalies impending great earthquakes have been observed in groundwater, thermal waters soil gas and in underground tunnels. Ileia is a very active tectonic site located in SW Greece, dominated by extensional active seismicity structures (e.g. Alfeios, Neda, Melpeia, Kiparissia-Aetos). Its instrumental and felt seismicity is very high, with more than 600 earthquakes of magnitude greater than 4.0 R in the last 100 years two of which occurred during the last 15 years and were very destructive (5.8 R on 26/3/93 and 6.8 R on 8/6/08 respectively). Hence, it is an area benefiting from the installation of a geophysical monitoring station, where radon exhalation associated with the accumulation or release of tectonic strain can be studied. In the aforementioned consensus, a station for the surveillance of soil radon has been installed in Kardamas Ileias, 3 km south from Amaliada which is the second highly populated city. The station consists of a high precision (calibration certified) active instrument (Alpha Guard-AG, Genitron Ltd.), equipped with an appropriate unit designed for pumping and measurement of radon in soil gas (Soil gas Unit, Genitron Ltd.). Soil radon is driven into AG via a 1-m probe (to minimize meteorological influences) and a 25-m radon proof 25-mm tube (to avoid simultaneous measurement of soil 220Rn

  9. Spontaneous adsorption of 3,5-bis(3,5-dinitrobenzoylamino) benzoic acid onto carbon

    Energy Technology Data Exchange (ETDEWEB)

    Paez, Julieta I.; Strumia, Miriam C. [Departamento de Quimica Organica (IMBIV-CONICET), Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba, Cordoba (5000) (Argentina); Passeggi, Mario C.G. [Laboratorio de Superficies e Interfaces (INTEC-CONICET), Facultad de Ingenieria Quimica, Universidad Nacional del Litoral, Santa Fe (3000) (Argentina); Ferron, Julio [Laboratorio de Superficies e Interfaces (INTEC-CONICET), Facultad de Ingenieria Quimica, Universidad Nacional del Litoral, Santa Fe (3000) (Argentina); Departamento de Materiales, Facultad de Ingenieria Quimica, Universidad Nacional del Litoral, Santa Fe (3000) (Argentina); Baruzzi, Ana M. [Departamento de Fisicoquimica (INFIQC-CONICET), Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba, Cordoba (5000) (Argentina); Brunetti, Veronica [Departamento de Fisicoquimica (INFIQC-CONICET), Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba, Cordoba (5000) (Argentina)], E-mail: brunetti@fcq.unc.edu.ar

    2009-07-01

    Dendritic molecules contain multifunctional groups that can be used to efficiently control the properties of an electrode surface. We are developing strategies to generate a highly functionalized surface using multifunctional and rigid dendrons immobilized onto different substrates. In the present work, we explore the immobilization of a dendritic molecule: 3,5-bis(3,5-dinitrobenzoylamino) benzoic acid (D-NO{sub 2}) onto carbon surfaces showing a simple and rapid way to produce conductive surfaces with electroactive chemical functions. The immobilized D-NO{sub 2} layer has been characterized using atomic force microscopy and cyclic voltammetry. D-NO{sub 2} adsorbs onto carbon surfaces spontaneously by dipping the electrode in dendron solutions. Reduction of this layer generates the hydroxylamine product. The resulting redox-active layer exhibits a well-behaved redox response for the adsorbed nitroso/hydroxylamine couple. The film permeability of the derivatized surface has been analyzed employing the electrochemical response of redox probes: Ru(NH{sub 3}){sub 6}{sup 3+}/Ru(NH{sub 3}){sub 6}{sup 2+} and Fe(CN){sub 6}{sup 3-}/Fe(CN){sub 6}{sup 4-}. Electrocatalytic oxidation of nicotinamide adenine dinucleotide onto a modified carbon surface was also observed.

  10. RAVE stars in K2. I. Improving RAVE red giants spectroscopy using asteroseismology from K2 Campaign 1

    Science.gov (United States)

    Valentini, M.; Chiappini, C.; Davies, G. R.; Elsworth, Y. P.; Mosser, B.; Lund, M. N.; Miglio, A.; Chaplin, W. J.; Rodrigues, T. S.; Boeche, C.; Steinmetz, M.; Matijevič, G.; Kordopatis, G.; Bland-Hawthorn, J.; Munari, U.; Bienaymé, O.; Freeman, K. C.; Gibson, B. K.; Gilmore, G.; Grebel, E. K.; Helmi, A.; Kunder, A.; McMillan, P.; Navarro, J.; Parker, Q. A.; Reid, W.; Seabroke, G.; Sharma, S.; Siviero, A.; Watson, F.; Wyse, R. F. G.; Zwitter, T.; Mott, A.

    2017-04-01

    We present a set of 87 RAVE stars with detected solar like oscillations, observed during Campaign 1 of the K2 mission (RAVE K2-C1 sample). This data set provides a useful benchmark for testing the gravities provided in RAVE data release 4 (DR4), and is key for the calibration of the RAVE data release 5 (DR5). The RAVE survey collected medium-resolution spectra (R = 7500) centred in the Ca II triplet(8600 Å) wavelength interval, which although being very useful for determining radial velocity and metallicity, even at low S/N, is known be affected by a log (g)-Teff degeneracy. This degeneracy is the cause of the large spread in the RAVE DR4 gravities for giants. The understanding of the trends and offsets that affects RAVE atmospheric parameters, and in particular log (g), is a crucial step in obtaining not only improved abundance measurements, but also improved distances and ages. In the present work, we use two different pipelines, GAUFRE and Sp_Ace, to determine atmospheric parameters and abundances by fixing log (g) to the seismic one. Our strategy ensures highly consistent values among all stellar parameters, leading to more accurate chemical abundances. A comparison of the chemical abundances obtained here with and without the use of seismic log (g) information has shown that an underestimated (overestimated) gravity leads to an underestimated (overestimated) elemental abundance (e.g. [Mg/H] is underestimated by 0.25 dex when the gravity is underestimated by 0.5 dex). We then perform a comparison between the seismic gravities and the spectroscopic gravities presented in the RAVE DR4 catalogue, extracting a calibration for log (g) of RAVE giants in the colour interval 0.50 gravities differ by more than 0.5 dex. The method illustrated in this work will be used for analysing RAVE targets present in the other K2 campaigns, in the framework of Galactic Archaeology investigations. Data (atmospheric parameters, abundances, distances, ages and reddening) are only

  11. The K2-ESPRINT Project. II. Spectroscopic Follow-up of Three Exoplanet Systems from Campaign 1 of K2

    Science.gov (United States)

    Van Eylen, Vincent; Nowak, Grzegorz; Albrecht, Simon; Palle, Enric; Ribas, Ignasi; Bruntt, Hans; Perger, Manuel; Gandolfi, Davide; Hirano, Teriyuki; Sanchis-Ojeda, Roberto; Kiilerich, Amanda; Prieto-Arranz, Jorge; Badenas, Mariona; Dai, Fei; Deeg, Hans J.; Guenther, Eike W.; Montañés-Rodríguez, Pilar; Narita, Norio; Béjar, Leslie A. Rogers ´ctor J. S., Vi; Shrotriya, Tushar S.; Winn, Joshua N.; Sebastian, Daniel

    2016-03-01

    We report on Doppler observations of three transiting planet candidates that were detected during Campaign 1 of the K2 mission. The Doppler observations were conducted with FIES, HARPS-N, and HARPS. We measure the mass of EPIC 201546283b, and provide constraints and upper limits for EPIC 201295312b and EPIC 201577035b. EPIC 201546283b is a warm Neptune orbiting its host star in 6.77 days and has a radius of {4.45}-0.33+0.33 {R}\\oplus and a mass of {29.1}-7.4+7.5 {M}\\oplus , which leads to a mean density of {1.80}-0.55+0.70 {{g}} {{cm}}-3. EPIC 201295312b is smaller than Neptune with an orbital period of 5.66 days, a radius of {2.75}-0.22+0.24 {R}\\oplus , and we constrain the mass to be below 12 {M}\\oplus at 95% confidence. We also find a long-term trend indicative of another body in the system. EPIC 201577035b, which was previously confirmed as the planet K2-10b, is smaller than Neptune, orbiting its host star in 19.3 days, with a radius of {3.84}-0.34+0.35 {R}\\oplus . We determine its mass to be {27}-16+17 {M}\\oplus , with a 95% confidence upper limit at 57 {M}\\oplus , and a mean density of {2.6}-1.6+2.1 {\\text{g cm}}-3. These measurements join the relatively small collection of planets smaller than Neptune with measurements or constraints of the mean density. Our code for performing K2 photometry and detecting planetary transits is now publicly available. Based on observations made with the NOT telescope under programme ID. 50-022/51-503 and 50-213(CAT), the TNG telescope under programme ID. AOT30.13, OPT15A_33, and CAT14B_121 and ESOs 3.6 m telescope at the La Silla Paranal Observatory under programme ID 095.C-0718(A).

  12. Transformation of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) by permanganate.

    Science.gov (United States)

    Chokejaroenrat, Chanat; Comfort, Steve D; Harris, Clifford E; Snow, Daniel D; Cassada, David; Sakulthaew, Chainarong; Satapanajaru, Tunlawit

    2011-04-15

    The chemical oxidant permanganate (MnO(4)(-)) has been shown to effectively transform hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) at both the laboratory and field scales. We treated RDX with MnO(4)(-) with the objective of quantifying the effects of pH and temperature on destruction kinetics and determining reaction rates. A nitrogen mass balance and the distribution of reaction products were used to provide insight into reaction mechanisms. Kinetic experiments (at pH ∼ 7, 25 °C) verified that RDX-MnO(4)(-) reaction was first-order with respect to MnO(4)(-) and initial RDX concentration (second-order rate: 4.2 × 10(-5) M(-1) s(-1)). Batch experiments showed that choice of quenching agents (MnSO(4), MnCO(3), and H(2)O(2)) influenced sample pH and product distribution. When MnCO(3) was used as a quenching agent, the pH of the RDX-MnO(4)(-) solution was relatively unchanged and N(2)O and NO(3)(-) constituted 94% of the N-containing products after 80% of the RDX was transformed. On the basis of the preponderance of N(2)O produced under neutral pH (molar ratio N(2)O/NO(3) ∼ 5:1), no strong pH effect on RDX-MnO(4)(-) reaction rates, a lower activation energy than the hydrolysis pathway, and previous literature on MnO(4)(-) oxidation of amines, we propose that RDX-MnO(4)(-) reaction involves direct oxidation of the methylene group (hydride abstraction), followed by hydrolysis of the resulting imides, and decarboxylation of the resulting carboxylic acids to form N(2)O, CO(2), and H(2)O.

  13. 28 CFR 3.5 - Forfeiture of gambling devices.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Forfeiture of gambling devices. 3.5 Section 3.5 Judicial Administration DEPARTMENT OF JUSTICE GAMBLING DEVICES § 3.5 Forfeiture of gambling devices. For purposes of seizure and forfeiture of gambling devices see section 8 of this chapter....

  14. Confirmation of Two Hot Jupiters from K2 Campaign 4

    CERN Document Server

    Johnson, Marshall C; Fridlund, Malcolm; Csizmadia, Szilard; Endl, Michael; Cabrera, Juan; Cochran, William D; Deeg, Hans J; Grziwa, Sascha; Ramírez, Ivan; Hatzes, Artie P; Eigmüller, Philipp; Barragán, Oscar; Erikson, Anders; Guenther, Eike W; Korth, Judith; Kuutma, Teet; Nespral, David; Pätzold, Martin; Palle, Enric; Prieto-Arranz, Jorge; Rauer, Heike; Saario, Joonas

    2016-01-01

    We confirm the planetary nature of two transiting hot Jupiters discovered by the Kepler spacecraft's K2 extended mission in its Campaign 4, using precise radial velocity measurements from FIES@NOT, HARPS-N@TNG, and the coud\\'e spectrograph on the McDonald Observatory 2.7 m telescope. EPIC 211089792 b transits a K1V star with a period of $3.2589263\\pm0.0000015$ days; its orbit is slightly eccentric ($e=0.086_{-0.025}^{+0.035}$). It has a radius of $R_P=0.998_{-0.066}^{+0.072}$ $R_J$ and a mass of $M_P=0.613_{-0.027}^{+0.028}$ $M_J$. Its host star exhibits significant rotational variability, and we measure a rotation period of $P_{\\mathrm{rot}}=10.777 \\pm 0.031$ days. EPIC 210957318 b transits a G6V star with a period of $4.098503\\pm0.000011$ days. It has a radius of $R_P=1.039_{-0.051}^{+0.050}$ $R_J$ and a mass of $M_P=0.579_{-0.027}^{+0.028}$ $M_J$. The star has a low metallicity for a hot Jupiter host, $[\\mathrm{Fe}/\\mathrm{H}]=-0.15 \\pm 0.05$.

  15. Computational study on structure and properties of new energetic material 3,7-bis(dinitromethylene-2,4,6,8-tetranitro-2,4,6,8-tetraaza-bicyclo[3.3.0]octane

    Directory of Open Access Journals (Sweden)

    Xinghui Jin

    2016-05-01

    Full Text Available The IR spectrum, crystal structure, electronic structure, thermodynamic properties, heat of formation and detonation properties of a new polynitro heterocyclic energetic material 3,7-bis(dinitromethylene-2,4,6,8-tetranitro-2,4,6,8-tetraazabicyclo[3.3.0]octane were investigated theoretically. The calculated results show that this compound has a centrosymmetric structure and the molecular packing prediction indicates that the crystalline packing of the title compound is P212121 and the corresponding cell parameters are as follows: Z=4, a= 22.03 Å, b=8.73 Å, c=8.42 Å, Ꮁ=90°, β=90° and γ=90°. Based on the high positive heat of formation (HOF, 740.4 kJ mol-1, excellent detonation properties (detonation velocity D, 9.77 km s−1; detonation pressure P, 45.9 GPa, energy gap (ΔELUMO-HOMO 4.19 eV and the molecular electrostatic potentials (MEP, it is predicted that 3,7-bis(dinitromethylene-2,4,6,8-tetranitro-2,4,6,8-tetraazabicyclo[3.3.0] octane could be may be a superior high-energy density compound (HEDC to RDX and HMX.

  16. Uncovering student thinking about mathematics in the common core, grades 6-8 25 formative assessment probes

    CERN Document Server

    Tobey, Cheryl Rose

    2013-01-01

    Pinpoint and reverse math misconceptions with laser-like accuracyQuickly and reliably uncover common math misconceptions in Grades 6-8 with these convenient and easy-to-implement diagnostic tools! Bestselling authors Cheryl Tobey and Carolyn Arline provide 25 new assessment probes that pinpoint subconcepts within the new Common Core Standards for Mathematics to promote deep learning and expert math instruction--while learning is already underway.Completely CCSM aligned, these grade-specific probes eliminate the guesswork and help teachers: Systematically address conceptual and procedural mistakes Help students better understand areas of struggle Plan targeted instruction that covers Grades 6-8 CCSM mathematical processes and proficiencies.

  17. Earth sciences within the project Ev-K2-CNR: Geodesy and geophysics; Le scienze della Terra nel progetto Ev-K2-CNR: Geodesia e geofisica

    Energy Technology Data Exchange (ETDEWEB)

    Poretti, Giorgio [Trieste, Univ. (Italy). Dipt. di Scienze Matematiche

    1997-05-01

    Earth Sciences started the Ev-K2-CNR project in 1987 with the comparison between the heights of Mt. Everest and K2. Several gravimetric campaigns followed in the most difficult areas of the Himalayas. In 1991 a GPS network was established in Nepal for the determination of the Earth crust movements in the area. In 1992 a precise measurement of mount Everest was performed with classical and satellite technologies. Mount K2 was remeasured in Summer 1996.

  18. Study on Charge Form Factors of the Exotic Nuclei 6,8He%奇特原子核6,8He的电荷形状因子研究

    Institute of Scientific and Technical Information of China (English)

    王再军; 任中洲

    2007-01-01

    应用相对论Eikonal近似计算了用不同模型给出的6,8He的电荷半径和电荷分布的形状因子,并将结果与6He和4He的实验结果进行了比较.结果显示不同模型给出的电荷半径和电荷形状因子差别很大,表明不同模型给出的晕中子与α核芯的关联有很大的差异.计算和讨论结果为在下一代电子-原子核对撞机上可能进行的实验提供了理论参考,同时,也为现有讨论奇特原子核的理论模型提供了检验.%Charge radius and charge form factors of different charge density distributions for 6,8He are calculated with the relativistic Eikonal approximation. Detailed comparisons and discussions are presented.It is found that the charge form factors curves of 6,8He are much lower than the experimental ones of 4He.This is, in principle, consistent with the experimental fact. Whereas detailed comparison among the charge form factors which correspond to different charge distributions show significant deviations. This indicates that the effects of the correlations between the halo neutrons and the α-core in 6,8He with different charge density distributions are quite different. This result would provide a useful reference for the possible experiments on the next-generation electron-nucleus collider and for the tests of different theoretical models for the exotic nuclei 6,8He.

  19. Associations between indoor environmental factors and parental-reported autistic spectrum disorders in children 6-8 years of age

    DEFF Research Database (Denmark)

    Larsson, Malin; Weiss, Bernard; Janson, Staffan

    2009-01-01

    ). The 2005 survey, based on the same children, now 6-8 years of age, also asked if, during the intervening period, the child had been diagnosed with Autism, Asperger's syndrome, or Tourette's syndrome. From a total of 4779 eligible children, 72 (60 boys, 12 girls) were identified with parentally reported...

  20. The K2 M67 Study: An Evolved Blue Straggler in M67 from K2 Mission Asteroseismology

    CERN Document Server

    Leiner, Emily; Stello, Dennis; Vanderburg, Andrew

    2016-01-01

    Yellow straggler stars (YSSs) fall above the subgiant branch in optical color-magnitude diagrams, between the blue stragglers and the red giants. YSSs may represent a population of evolved blue stragglers, but none have the direct and precise mass and radius measurements needed to determine their evolutionary states and formation histories. Here we report the first asteroseismic mass and radius measurements of such a star, the yellow straggler S1237 in the open cluster M67. We apply asteroseismic scaling relations to a frequency analysis of the Kepler K2 light curve and find a mass of 2.9 $\\pm$ 0.2 M$_{\\odot}$ and a radius of 9.2 $\\pm$ 0.2 R$_{\\odot}$. This is more than twice the mass of the main- sequence turnoff in M67, suggesting S1237 is indeed an evolved blue straggler. S1237 is the primary in a spectroscopic binary. We update the binary orbital solution and use spectral energy distribution (SED) fitting to constrain the color-magnitude diagram (CMD) location of the secondary star. We find that the secon...

  1. 维生素K2及其配伍制剂抗实验性骨质疏松症的筛选研究%Anti-osteoporotic screening study of vitamin K2 and its compatibility of medicines

    Institute of Scientific and Technical Information of China (English)

    陈鹏; 何波; 杨仁华; 陆义芹; 沈志强

    2013-01-01

    ; vitamin K2 (80 g/kg) + calcium citrate (500 mg/kg), sample 5: vitamin K2 (50 g/kg) + vitamin D3 (4 g/kg), sample 6: vitamin K2 (80 g/kg) + vitamin D3 (4 g/kg), sample 7: vitamin K2 (50 g/kg) + vitamin E (40 mg/kg), sample 8: vitamin K2 (80 g/kg ) + vitamin E (40 mg/kg), sample 9: vitamin K2 (50 g/kg) + vitamin E (40 mg/kg) + vitamin D3 (4 g/kg), sample 10: vitamin K2 (80 g/kg) + vitamin E (40 mg/kg) +- vitamin D3 (4 g/kg), sample 11: vitamin K2 (50 g/kg ) + vitamin E (40 mg/kg) + calcium citrate (500 mg/kg), sample 12: vitamin K2 (80 g/kg ) + vitamin E (40 mg/kg) + calcium citrate (500 mg/kg), sample 13: vitamin K2 (50 g/kg) + vitamin D3 (4 g/kg) + calcium citrate (500 mg/ kg), and sample 14: vitamin K2 (80 g/kg) + vitamin D3 (4 g/kg) + calcium citrate (500 mg/kg). Female Sprague-dawly rats were randomly divided into normal control group, sham operation group, and ovariectomized (OVX) group. Rat osteoporosis model was established using OVX. Rats in OVX group were then randomly divided into model group, 30μg/kg diethylstilbestrol positive control group, and the above 14 test sample groups, respectively. Rats in 14 test sample groups were given a 1ml/100g administration of the samples intragastrically once a day, lasting for 60 days. Normal saline was used in normal control group, and peanut oil was used in sham and model groups, respectively. The detailed grouping was shown in Table 1. Bone mineral density (BMD) and bone mineral content (BMC) were examined by dual-energy X-ray absorptiometry analysis, and bone calcium by atomic absorption, respectively. Results Effect on BMD and BMC : as compared with that in model group, test sample 13 and 14 could significantly improve BMD and BMC of the femur and the vertebrae ( P < 0. 01). The effect of test sample 14 was stronger than that of test sample 13 (P < 0. 05). Test sample 1 and test samples 2, 4, 6, 8, 10, and 12 ( combined with the same dose of test sample 1) could increase BMD and BMC of the femur and the vertebrae

  2. Altered expression of two-pore domain potassium (K2P channels in cancer.

    Directory of Open Access Journals (Sweden)

    Sarah Williams

    Full Text Available Potassium channels have become a focus in cancer biology as they play roles in cell behaviours associated with cancer progression, including proliferation, migration and apoptosis. Two-pore domain (K2P potassium channels are background channels which enable the leak of potassium ions from cells. As these channels are open at rest they have a profound effect on cellular membrane potential and subsequently the electrical activity and behaviour of cells in which they are expressed. The K2P family of channels has 15 mammalian members and already 4 members of this family (K2P2.1, K2P3.1, K2P9.1, K2P5.1 have been implicated in cancer. Here we examine the expression of all 15 members of the K2P family of channels in a range of cancer types. This was achieved using the online cancer microarray database, Oncomine (www.oncomine.org. Each gene was examined across 20 cancer types, comparing mRNA expression in cancer to normal tissue. This analysis revealed all but 3 K2P family members (K2P4.1, K2P16.1, K2P18.1 show altered expression in cancer. Overexpression of K2P channels was observed in a range of cancers including breast, leukaemia and lung while more cancers (brain, colorectal, gastrointestinal, kidney, lung, melanoma, oesophageal showed underexpression of one or more channels. K2P1.1, K2P3.1, K2P12.1, were overexpressed in a range of cancers. While K2P1.1, K2P3.1, K2P5.1, K2P6.1, K2P7.1 and K2P10.1 showed significant underexpression across the cancer types examined. This analysis supports the view that specific K2P channels may play a role in cancer biology. Their altered expression together with their ability to impact the function of other ion channels and their sensitivity to environmental stimuli (pO2, pH, glucose, stretch makes understanding the role these channels play in cancer of key importance.

  3. Mass determination of K2-19b and K2-19c from radial velocities and transit timing variations

    CERN Document Server

    Nespral, D; Deeg, H J; Borsato, L; Fridlund, M C V; Barragan, O; Grziwa, S; Korth, J; Cabrera, J; Csizmadia, Sz; Nowak, G; Kuutma, T; Saario, J; Eigmuller, P; Erikson, A; Guenther, E W; Hatzes, A P; Rodriguez, P Montanes; Palle, E; Patzold, M; Prieto-Arranz, J; Rauer, H; Sebastian, D

    2016-01-01

    We present FIES@NOT and HARPS-N@TNG radial velocity follow-up observations of K2-19, a compact planetary system hosting three planets, of which the two larger ones, namely K2-19b and K2-19c, are close to the 3:2 mean motion resonance. The masses of these larger planets have previously been derived from transit timing only. An analysis considering only the radial velocity measurements is able to detect only K2-19b, the largest and more massive planet in the system, with a mass of $71.7\\pm6.3$ M${_\\oplus}$. We also used the TRADES code to simultaneously model both our RV measurements and the existing transit-timing measurements. We derived a mass of K2-19b of $59.5^{+7.2}_{-11.4}$ M${_\\oplus}$ and of K2-19c of $9.7^{+3.9}_{-2.0}$ M${_\\oplus}$. A prior K2-19b mass estimated by Barros 2015, based exclusively on transit timing measurements, is only consistent with our combined TTV and RV analysis, but not with our analysis based purely on RV measurements. K2-19b supports the suspicion that planet masses and densit...

  4. FoxK2 is Required for Cellular Proliferation and Survival

    NARCIS (Netherlands)

    van der Heide, Lars P.; Wijchers, Patrick J. E. C.; von Oerthel, Lars; Burbach, J. Peter H.; Hoekman, Marco F. M.; Smidt, Marten P.

    2015-01-01

    FoxK2 is a forkhead transcription factor expressed ubiquitously in the developing murine central nervous system. Here we investigated the role of FoxK2 in vitro and focused on proliferation and cellular survival. Knockdown of FoxK2 results in a decrease in BrdU incorporation and H3 phosphorylation,

  5. FoxK2 is required for cellular proliferation and survival

    NARCIS (Netherlands)

    van der Heide, L.P.; Wijchers, P.J.E.C.; von Oerthel, L.; Burbach, J.P.H.; Hoekman, M.F.M.; Smidt, M.P.

    2015-01-01

    FoxK2 is a forkhead transcription factor expressed ubiquitously in the developing murine central nervous system. Here we investigated the role of FoxK2 in vitro and focused on proliferation and cellular survival. Knockdown of FoxK2 results in a decrease in BrdU incorporation and H3 phosphorylation,

  6. Roles of kallikrein-2 biomarkers (free-hK2 and pro-hK2 for predicting prostate cancer progression-free survival

    Directory of Open Access Journals (Sweden)

    Anatilde Gonzalez Guerrico

    2017-07-01

    Full Text Available Free human kallikrein 2 (free-hK2 and hK2 pro-form (pro-hK2 have been found to be increased in tumor tissues and serum from patients with prostate cancer. We established semiautomatic assays for free-hK2 and pro-hK2 using a research version of the Beckman Coulter ACCESS2 system. Serum samples from a cohort of 189 men undergoing radical prostatectomy for known high-risk disease were assayed for Prostate-Specific Antigen (PSA, free-PSA, free-hK2, and pro-hK2. Univariate Cox regression and multivariate models were used to predict both Gleason scores and progression-free survival (PFS. Free-hk2 levels ≥80 ng/L were predictive of both Gleason scores ≥7 ( p = 0.04 and PFS ( p = 0.03. PSA ≥8.0 µg/L also was predictive of PFS ( p = 0.02. However, neither % free-PSA nor pro-hK2, when treated as continuous or cutoff variables were associated with Gleason score or PFS. Multivariable models showed that clinical stage T1c versus T2/T3, Gleason score ≥7, and PSA ≥8.0 µg/L or clinical stage T1c versus T2/T3, Gleason scores ≥7, and free-hK2 ≥80 ng/L were among the best models predicting PFS. Both free-hK2 and PSA in conjunction with clinical stage and Gleason score are good predictors of PFS in prostate cancer.

  7. Comparative Study of Multiplet Structures of Mn4+ in K2SiF6, K2GeF6, and K2TiF6 Based on First-Principles Configuration-Interaction Calculations

    Science.gov (United States)

    Novita, Mega; Ogasawara, Kazuyoshi

    2012-02-01

    We performed first-principles configuration-interaction calculations of multiplet energies for Mn4+ in K2SiF6, K2GeF6, and K2TiF6 crystals. The results indicate that corrections based on a single-electron calculation are effective for the prediction of 4A2 → 4T2 and 4A2 → 4T1a transition energies, while such corrections are not necessary for the prediction of the 4A2 → 2E transition energy. The cluster size dependence of the multiplet energies is small. However, the 4A2 → 2E transition energy is slightly improved by using larger clusters including K ions. The theoretical multiplet energies are improved further by considering the lattice relaxation effect. As a result, the characteristic multiplet energy shifts depending on the host crystal are well reproduced without using any empirical parameters. Although K2GeF6 and K2TiF6 have lower symmetry than K2SiF6, the results indicate that the variation of the multiplet energy is mainly determined by the Mn-F bond length.

  8. 6,8-Dibromoquinoline

    Directory of Open Access Journals (Sweden)

    Ísmail Çelik

    2010-11-01

    Full Text Available The title molecule, C9H5Br2N, is almost planar, with an r.m.s. deviation of 0.027 Å. The dihedral angle between the aromatic rings is 1.5 (3°. In the crystal, π–π stacking interactions are present between the pyridine and benzene rings of adjacent molecules [centroid–centroid distances = 3.634 (4 Å], and short Br...Br contacts [3.4443 (13 Å] occur.

  9. Two Small Temperate Planets Transiting Nearby M Dwarfs in K2 Campaigns 0 and 1

    CERN Document Server

    Schlieder, Joshua E; Petigura, Erik A; Howard, Andrew W; Aller, Kimberly M; Sinukoff, Evan; Isaacson, Howard T; Fulton, Benjamin J; Ciardi, David R; Bonnefoy, Mickael; Ziegler, Carl; Morton, Timothy D; Lepine, Sebastien; Obermeier, Christian; Liu, Michael C; Bailey, Vanessa P; Baranec, Christoph; Beichman, Charles A; Defrere, Denis; Henning, Thomas; Hinz, Philip; Law, Nicholas; Riddle, Reed; Skemer, Andrew

    2016-01-01

    The prime Kepler mission revealed that small planets (<4 R_earth) are common, especially around low-mass M dwarfs. K2, the re-purposed Kepler mission, continues this exploration of small planets around small stars. Here we combine K2 photometry with spectroscopy, adaptive optics imaging, and archival survey images to analyze two small planets orbiting the nearby, field age, M dwarfs K2-26 (EPIC 202083828) and K2-9. K2-26 is an M1.0 +/- 0.5 dwarf at 93 +/- 7 pc from K2 Campaign 0. We validate its 14.5665 d period planet and estimate a radius of 2.67^+0.46_-0.42 R_earth. K2-9 is an M2.5 +/- 0.5 dwarf at 110 +/- 12 pc from K2 Campaign 1. K2-9b was first identified by Montet et al. 2015; here we present spectra and adaptive optics imaging of the host star and independently validate and characterize the planet. Our analyses indicate K2-9b is a 2.25^+0.53_-0.96 R_earth planet with a 18.4498 d period. K2-26b exhibits a transit duration that is too long to be consistent with a circular orbit given the measured ste...

  10. K2-66b and K2-106b: Two Extremely Hot Sub-Neptune-size Planets with High Densities

    Science.gov (United States)

    Sinukoff, Evan; Howard, Andrew W.; Petigura, Erik A.; Fulton, Benjamin J.; Crossfield, Ian J. M.; Isaacson, Howard; Gonzales, Erica; Crepp, Justin R.; Brewer, John M.; Hirsch, Lea; Weiss, Lauren M.; Ciardi, David R.; Schlieder, Joshua E.; Benneke, Bjoern; Christiansen, Jessie L.; Dressing, Courtney D.; Hansen, Brad M. S.; Knutson, Heather A.; Kosiarek, Molly; Livingston, John H.; Greene, Thomas P.; Rogers, Leslie A.; Lépine, Sébastien

    2017-06-01

    We report precise mass and density measurements of two extremely hot sub-Neptune-size planets from the K2 mission using radial velocities, K2 photometry, and adaptive optics imaging. K2-66 harbors a close-in sub-Neptune-sized ({2.49}-0.24+0.34 {R}\\oplus ) planet (K2-66b) with a mass of 21.3+/- 3.6 {M}\\oplus . Because the star is evolving up the subgiant branch, K2-66b receives a high level of irradiation, roughly twice the main-sequence value. K2-66b may reside within the so-called “photoevaporation desert,” a domain of planet size and incident flux that is almost completely devoid of planets. Its mass and radius imply that K2-66b has, at most, a meager envelope fraction (radiation environments. Their high densities reflect the challenge of retaining a substantial gas envelope in such extreme environments.

  11. Analyzing Kepler/K2 pixel data using open source tools

    Science.gov (United States)

    Barentsen, Geert

    2016-06-01

    I will demonstrate three new open source command-line tools which have been developed at Kepler/K2 Guest Observer Office to help the community analyze and interpret pixel data from NASA's K2 mission: (1) "k2flix" enables the visual inspection of pixel files for artifacts; (2) "k2mosaic" enables pixel files to be mosaiced into contiguous images; and (3) "k2lightcurve" extracts and detrends photometry. I will also highlight the "k2ephem" and "k2fov" tools which aid target selection, and the "kadenza" tool which enables access to the raw spacecraft data during the Campaign 9 microlensing experiment. Finally, I will explain how these tools may be adapted to aid the upcoming TESS and PLATO missions.

  12. Seven years of postseismic deformation following the 2003 Mw = 6.8 Zemmouri earthquake (Algeria) from InSAR time series

    KAUST Repository

    Cetin, Esra

    2012-05-28

    We study the postseismic surface deformation of the Mw 6.8, 2003 Zemmouri earthquake (northern Algeria) using the Multi-Temporal Small Baseline InSAR technique. InSAR time series obtained from 31 Envisat ASAR images from 2003 to 2010 reveal sub-cm coastline ground movements between Cap Matifou and Dellys. Two regions display subsidence at a maximum rate of 2 mm/yr in Cap Djenet and 3.5 mm/yr in Boumerdes. These regions correlate well with areas of maximum coseismic uplifts, and their association with two rupture segments. Inverse modeling suggest that subsidence in the areas of high coseismic uplift can be explained by afterslip on shallow sections (<5 km) of the fault above the areas of coseismic slip, in agreement with previous GPS observations. The earthquake impact on soft sediments and the ground water table southwest of the earthquake area, characterizes ground deformation of non-tectonic origin. The cumulative postseismic moment due to 7 years afterslip is equivalent to an Mw 6.3 earthquake. Therefore, the postseismic deformation and stress buildup has significant implications on the earthquake cycle models and recurrence intervals of large earthquakes in the Algiers area.

  13. 21 CFR 176.230 - 3,5-Dimethyl-1,3,5,2H-tetrahydrothiadiazine-2-thione.

    Science.gov (United States)

    2010-04-01

    ... or technical effect in the food itself. (c) The use of a preservative in any substance or article... 21 Food and Drugs 3 2010-04-01 2009-04-01 true 3,5-Dimethyl-1,3,5,2H-tetrahydrothiadiazine-2-thione. 176.230 Section 176.230 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH...

  14. Dissociative Electron Attachment to the Nitroamine HMX (Octahydro-1,3,5,7-Tetranitro-1,3,5,7-Tetrazocine)

    National Research Council Canada - National Science Library

    Postler, Johannes; Goulart, Marcelo M; Matias, Carolina; Mauracher, Andreas; da Silva, Filipe Ferreira; Scheier, Paul; Limão-Vieira, Paulo; Denifl, Stephan

    2013-01-01

    In the present study, dissociative electron attachment (DEA) measurements with gas phase HMX, octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine, C4H8N8O8, have been performed by means of a crossed electron-molecular beam experiment...

  15. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (Rdx) (Public Comment Draft)

    Science.gov (United States)

    EPA is developing an Integrated Risk Information System (IRIS) assessment of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and has released the draft assessment for public comment. When final, the assessment will appear on the IRIS database.

  16. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (Rdx) (Interagency Science Consultation Draft)

    Science.gov (United States)

    On March 10, 2016, the public comment draft Toxicological Review of Hexahydro-1,3,5-trinitro-1,3,5-triazine and the draft charge to external peer reviewers were released for public review and comment. The Toxicological Review and charge were reviewed internally by EPA and by othe...

  17. IRIS Toxicological Review of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (Rdx) (External Review Draft)

    Science.gov (United States)

    The IRIS Toxicological Review of Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) was released for external peer review in September 2016. The EPA’s Science Advisory Board’s (SAB) Chemical Assessment Advisory Committee (CAAC) will conduct a peer review of the scientific basis suppor...

  18. Identification of ovine ruminal microbes capable of biotransforming hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX)

    Science.gov (United States)

    Bioremediation is of great interest in the detoxification of soil contaminated with residues from explosives such as hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). Although there are numerous forms of in situ and ex situ bioremediation, ruminants would provide the option of an in situ bioreactor tha...

  19. Ramsey Number of K2,s+1 vs. K1,n%关于K2,s+1 VS,K1,n的Ramsey数

    Institute of Scientific and Technical Information of China (English)

    秦大伟; 沈大鹏

    2007-01-01

    It is shown that the Ramsey number r(K2,s+1, K1,n) ≤ n + √sn+ (s + 3)/2 + o(1) for large n, and r(K2,s+1, K1,n)∈{(q-1)2/s+1,-(q-1)2/s+2},wheren: (q-1)2/s-q+2 and q is a prime power such that s|(q - 1).

  20. Metastable Equilibrium in Quaternary System Li2SO4+K2SO4+Li2CO3+K2CO3+H2O at 288 K

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Metastable equilibrium solubilities and densities of the Li2SO4+K2SO4+Li2CO3+K2CO3+H2O system at 288 K were determined experimentally by using the isothermal evaporation method. According to the experimental data, the metastable equilibrium solubility phase diagram was constructed. In the phase diagram, there are three invariate( Li2CO3 ) has the smallest solubility in the quaternary system.

  1. N-[(3,5-Dimethylpyrazol-1-yl)methyl]phthalimide

    OpenAIRE

    Huan-Qiang Liu; Fang-Fang Jian; Su-Qing Wang

    2008-01-01

    The title compound {systematic name: 2-[(3,5-dimenthylpyrazol-1-yl)methyl]isoindole-1,3-dione}, C14H13N3O2, was prepared by reaction of N-(bromomethyl)phthalimide and 3,5-dimethylpyrazole in chloroform solution. The molecular structure and packing are stabilized by intramolecular C—H...O hydrogen-bonding and C—H...π interactions.

  2. N-[(3,5-Dimethylpyrazol-1-ylmethyl]phthalimide

    Directory of Open Access Journals (Sweden)

    Huan-Qiang Liu

    2008-09-01

    Full Text Available The title compound {systematic name: 2-[(3,5-dimenthylpyrazol-1-ylmethyl]isoindole-1,3-dione}, C14H13N3O2, was prepared by reaction of N-(bromomethylphthalimide and 3,5-dimethylpyrazole in chloroform solution. The molecular structure and packing are stabilized by intramolecular C—H...O hydrogen-bonding and C—H...π interactions.

  3. Screening the budding yeast genome reveals unique factors affecting K2 toxin susceptibility.

    Directory of Open Access Journals (Sweden)

    Elena Servienė

    Full Text Available BACKGROUND: Understanding how biotoxins kill cells is of prime importance in biomedicine and the food industry. The budding yeast (S. cerevisiae killers serve as a convenient model to study the activity of biotoxins consistently supplying with significant insights into the basic mechanisms of virus-host cell interactions and toxin entry into eukaryotic target cells. K1 and K2 toxins are active at the cell wall, leading to the disruption of the plasma membrane and subsequent cell death by ion leakage. K28 toxin is active in the cell nucleus, blocking DNA synthesis and cell cycle progression, thereby triggering apoptosis. Genome-wide screens in the budding yeast S. cerevisiae identified several hundred effectors of K1 and K28 toxins. Surprisingly, no such screen had been performed for K2 toxin, the most frequent killer toxin among industrial budding yeasts. PRINCIPAL FINDINGS: We conducted several concurrent genome-wide screens in S. cerevisiae and identified 332 novel K2 toxin effectors. The effectors involved in K2 resistance and hypersensitivity largely map in distinct cellular pathways, including cell wall and plasma membrane structure/biogenesis and mitochondrial function for K2 resistance, and cell wall stress signaling and ion/pH homeostasis for K2 hypersensitivity. 70% of K2 effectors are different from those involved in K1 or K28 susceptibility. SIGNIFICANCE: Our work demonstrates that despite the fact that K1 and K2 toxins share some aspects of their killing strategies, they largely rely on different sets of effectors. Since the vast majority of the host factors identified here is exclusively active towards K2, we conclude that cells have acquired a specific K2 toxin effectors set. Our work thus indicates that K1 and K2 have elaborated different biological pathways and provides a first step towards the detailed characterization of K2 mode of action.

  4. Studies on the Electrochemical Characteristics of K2FeO4 Electrode

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Discharge performance of K2FeO4 electrode under different conditions was studied by the constant electric current discharge method. The electrochemical characteristics of K2FeO4 electrode were investigated for the first time by means of cyclic voltammetry. The results show that the K2FeO4 electrode made at moderate pressure (20 MPa) and discharged at lower current has better discharge performance. It is also found that K2FeO4 electrode is significantly rechargeable.

  5. On the Meshing Efficiency of 2K-2H Type Planetary Gear Reducer

    OpenAIRE

    Long-Chang Hsieh; Hsiu-Chen Tang

    2013-01-01

    This paper proposes 2K-2H type planetary gear reducer and analyzes its meshing efficiency. First, according to the concept of train value equation, the kinematic design of 2K-2H type planetary gear reducers is carried out. Three 2K-2H type planetary gear reducers are designed to illustrate the design algorithm. Then, based on the latent power theorem, the meshing efficiency equation of 2K-2H type planetary gear reducer is derived. According to the meshing efficiency equation, the meshing effi...

  6. Tracking Down the Source Population Responsible for the Unresolved Cosmic 6-8 keV Background

    CERN Document Server

    Xue, Y Q; Brandt, W N; Luo, B; Alexander, D M; Bauer, F E; Comastri, A; Fabian, A C; Gilli, R; Lehmer, B D; Schneider, D P; Vignali, C; Young, M

    2012-01-01

    Using the 4 Ms Chandra Deep Field-South (CDF-S) survey, we have identified a sample of 6845 X-ray undetected galaxies that dominates the unresolved ~ 20-25% of the 6-8 keV cosmic X-ray background (XRB). This sample was constructed by applying mass and color cuts to sources from a parent catalog based on GOODS-South HST z-band imaging of the central 6'-radius area of the 4 Ms CDF-S. The stacked 6-8 keV detection is significant at the 3.9 sigma level, but the stacked emission was not detected in the 4-6 keV band which indicates the existence of an underlying population of highly obscured active galactic nuclei (AGNs). Further examinations of these 6845 galaxies indicate that the galaxies on the top of the blue cloud and with redshifts of 1 ~1E10 M_sun) galaxies. We discuss constraints upon this underlying AGN population, supporting evidence for relatively low-mass galaxies hosting highly obscured AGNs, and prospects for further boosting the stacked signal.

  7. Ocean Sciences Sequence for Grades 6-8: Climate Change Curriculum Developed Through a Collaboration Between Scientists and Educators

    Science.gov (United States)

    Weiss, E.; Skene, J.; Tran, L.

    2011-12-01

    Today's youth have been tasked with the overwhelming job of addressing the world's climate future. The students who will become the scientists, policy makers, and citizens of tomorrow must gain a robust understanding of the causes and effects of climate change, as well as possible adaptation strategies. Currently, there are few high quality curricula available to teachers that address these topics in a developmentally appropriate manner. The NOAA-funded Ocean Sciences Sequence for Grades 6-8 aims to address this gap by providing teachers with scientifically accurate climate change curriculum that hits on some of the most salient points in climate science, while simultaneously developing students' science process skills. The Ocean Sciences Sequence for Grades 6-8 is developed through a collaboration between some of the nation's leading ocean and climate scientists and the Lawrence Hall of Science's highly qualified GEMS (Great Explorations in Math & Science) curriculum development team. Scientists are active partners throughout the whole development process, from initial brainstorming of key concepts and creating the conceptual storyline for the curriculum to final review of the content and activities. As with all GEMS Sequences, the Ocean Sciences Sequence for Grades 6-8 is designed to provide significant scientific and educational depth, systematic assessments and informational readings, and incorporate new learning technologies. The goal is to focus strategically and effectively on the core concepts within ocean and climate sciences that students need to understand. This curriculum is designed in accordance with the latest research from the learning sciences, and provides numerous opportunities for students to develop inquiry skills and abilities as they learn about the practice of science through hands-on activities. The Ocean Sciences Sequence for Grades 6-8 addresses in depth a significant number of national, state, and district standards and benchmarks. It

  8. Primary Dermal Irritation of 1-Acetyloctahydro-3,5,7-Trinitro-1,3,5,7-Tetrazine.

    Science.gov (United States)

    1983-06-01

    Tetrazine Chemical Abstract 3ervice F ;istry V" 139800-00-2 Lewis--2 Structural formula: C-CH3 H C N-NO2 02 N-N H2 H4X-N Empirical formula: C6H11N7...CHEMICAL DATA Chemical name: 1-Acetyloctahydro-3,5,7-Trinitro-1,3,5,7-Tetrazine Chemical Abstract Service Registry No.: 139800-00-2 Structural formula

  9. Biodegradation of hexahydro-1,3,5-trinitro-1,3,5-triazine and its mononitroso derivative hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine by Klebsiella pneumoniae strain SCZ-1 isolated from an anaerobic sludge.

    Science.gov (United States)

    Zhao, Jian-Shen; Halasz, Annamaria; Paquet, Louise; Beaulieu, Chantale; Hawari, Jalal

    2002-11-01

    In previous work, we found that an anaerobic sludge efficiently degraded hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), but the role of isolates in the degradation process was unknown. Recently, we isolated a facultatively anaerobic bacterium, identified as Klebsiella pneumoniae strain SCZ-1, using MIDI and the 16S rRNA method from this sludge and employed it to degrade RDX. Strain SCZ-1 degraded RDX to formaldehyde (HCHO), methanol (CH3OH) (12% of total C), carbon dioxide (CO(2)) (72% of total C), and nitrous oxide (N2O) (60% of total N) through intermediary formation of methylenedinitramine (O(2)NNHCH(2)NHNO(2)). Likewise, hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (MNX) was degraded to HCHO, CH3OH, and N2O (16.5%) with a removal rate (0.39 micromol. h(-1). g [dry weight] of cells(-1)) similar to that of RDX (0.41 micromol. h(-1). g [dry weight] of cells(-1)) (biomass, 0.91 g [dry weight] of cells. liter(-1)). These findings suggested the possible involvement of a common initial reaction, possibly denitration, followed by ring cleavage and decomposition in water. The trace amounts of MNX detected during RDX degradation and the trace amounts of hexahydro-1,3-dinitroso-5-nitro-1,3,5-triazine detected during MNX degradation suggested that another minor degradation pathway was also present that reduced -NO2 groups to the corresponding -NO groups.

  10. Using K2 to Investigate Planetary Systems Orbiting Low-Mass Stars

    Science.gov (United States)

    Dressing, Courtney D.; Newton, Elisabeth R.; Charbonneau, David; Schlieder, Joshua E.; K2 CHAI Consortium

    2016-10-01

    The NASA K2 mission is using the repurposed Kepler spacecraft to search for transiting planets in multiple fields along the ecliptic plane. Unlike the original Kepler mission, which stared at a single region of the sky for four years, K2 observes each field for a much shorter timespan of roughly 80 days. While planets in the habitable zones of Sun-like stars would be unlikely to transit even once during an 80-day interval, planets in the habitable zones of faint low-mass stars have much shorter orbital periods and may even transit multiple times during a single K2 campaign. Accordingly, M and K dwarfs are frequently nominated as K2 Guest Observer targets and K2 has already observed significantly more low-mass stars than the original Kepler mission. While the K2 data are therefore an enticing resource for studying the properties and frequency of planetary systems orbiting low-mass stars, many K2 target stars are not well-characterized and some candidate low-mass stars are actually giants or reddened Sun-like stars. We are improving the characterization of K2 planetary systems orbiting low-mass stars by using SpeX on the NASA Infrared Telescope Facility and TripleSpec on the 200-inch Hale Telescope at Palomar Observatory to acquire near-infrared spectra of K2 target stars. We then employ empirically-based relations to determine the temperatures, radii, luminosities, and metallicities of K2 planet candidate host stars. Refining the stellar parameters allows us to identify astrophysical false positives and better constrain the radii and insolation flux environments of bona fide transiting planets. I will present our resulting catalog of stellar properties and discuss the prospects for using K2 data to investigate whether planet occurrence rates for mid-M dwarfs are similar to those for early-M and late-K dwarfs.

  11. Tau Tubulin Kinase TTBK2 Sensitivity of Glutamate Receptor GluK2

    Directory of Open Access Journals (Sweden)

    Kristina Nieding

    2016-09-01

    Full Text Available Background/Aims: Inherited, autosomal dominant spinocerebellar ataxia type 11 (SCA11 is caused by loss of function mutations of TTBK2 (tau tubulin kinase 2. Mutations observed in patients with SCA11 include truncated TTBK2(450. The present study explored the possibility that TTBK2 influences the function of the glutamate receptor GluK2. Methods: GluK2 was expressed in Xenopus oocytes without and with additional expression of wild type TTBK2, the truncated mutant TTBK2(450, or the kinase dead mutants TTBK2(KD and TTBK2(450/KD. GluK2 current was determined by dual electrode voltage clamp and GluK2 protein abundance in the cell membrane utilizing confocal microscopy. Results: Glutamate exposure of GluK2 expressing oocytes generated a current, which was significantly lower in oocytes expressing GluK2 together with TTBK2 wt or TTBK2(KD than in oocytes expressing GluK2 alone or together with either TTBK2(450 or TTBK2(450/KD. According to confocal microscopy of EGFP-tagged GluK2, TTBK2 wt decreased the GluK2 protein abundance in the cell membrane. Overexpression of an inactive RAB5(N133I mutant but not RAB5wt could reverse the TTBK2 effect on GluK2 suggesting that RAB5 function is required for the effect. Conclusions: TTBK2 down-regulates GluK2 activity by decreasing the receptor protein abundance in the cell membrane via RAB5-dependent endocytosis, an effect that may protect against neuroexcitotoxicity.

  12. Study on pseudothrombocytopenia caused by anticoagulant EDTA-K2%抗凝剂EDTA-K2致血小板假性减少探讨

    Institute of Scientific and Technical Information of China (English)

    唐健辰

    2010-01-01

    目的 探讨乙二胺四乙酸二钾(EDTA-K2)抗凝剂对假性血小板减少(PTCP)的影响及解决方法 .方法 对10例PTCP患者及30名健康体检者在EDTA-K2抗凝静脉血放置1 h后,用全自动血液分析仪进行分析,同时用手工计数血小板(PLT)作为参考值,并以不加抗凝剂的指血直接稀释后在全自动血液分析仪上测定.结果 EDTA-K2抗凝血PLT计数结果 与手工法相比,差异有统计学意义(P0.05),患者加EDTA-K2抗凝血作涂片瑞-姬染色,发现血片中有大量PLT聚集,聚集的PLT大小不一、数量不等,而不加抗凝剂的患者指血,则无PLT聚集现象.结论 EDTA-K2对PLT可产生聚集作用,引起PTCP.

  13. K2-60b and epic 216468514b. A sub-jovian and a jovian planet from the k2 mission

    CERN Document Server

    Eigmüller, Philipp; Persson, Carina M; Donati, Paolo; Fridlund, Malcolm; Csizmadia, Szilard; Barragán, Oscar; Smith, Alexis M S; Cabrera, Juan; Korth, Judith; Grziwa, Sascha; Prieto-Arranz, Jorge; Nespral, David; Saario, Joonas; Cochran, William D; Cusano, Felice; Deeg, Hans J; Endl, Michael; Erikson, Anders; Guenther, Eike W; Hatzes, Artie P; Pätzold, Martin; Rauer, Heike

    2016-01-01

    We report the characterization and independant detection of K2-60b, as well as the detection and characterization of EPIC 216468514b, two transiting hot gaseous planets from the K2 space mission. We confirm the planetary nature of the two systems and determine their fundamental parameters combining the K2 time-series data with FIES@NOT and HARPS-N@TNG spectroscopic observations. K2-60b has a radius of 0.683 +/- 0.037 RJup and a mass of 0.426 +/- 0.037 MJup and orbits a G4V star with an orbital period of 3.00267 +/- 0.00006 days. EPIC 216468514b has a radius of 1.44 +/- 0.15RJup and a mass of 0.84 +/- 0.08 MJup and orbits an F9 IV star every 3.31392 +/- 0.00002 days. K2-60b is among the few planets at the edge of the so-called "desert" of short-period sub Jovian planets. EPIC 216468514b is a highly inflated Jovian planet orbiting an evolved star about to leave the main sequence.

  14. Biodegradation of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine and Its Mononitroso Derivative Hexahydro-1-Nitroso-3,5-Dinitro-1,3,5-Triazine by Klebsiella pneumoniae Strain SCZ-1 Isolated from an Anaerobic Sludge

    OpenAIRE

    2002-01-01

    In previous work, we found that an anaerobic sludge efficiently degraded hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), but the role of isolates in the degradation process was unknown. Recently, we isolated a facultatively anaerobic bacterium, identified as Klebsiella pneumoniae strain SCZ-1, using MIDI and the 16S rRNA method from this sludge and employed it to degrade RDX. Strain SCZ-1 degraded RDX to formaldehyde (HCHO), methanol (CH3OH) (12% of total C), carbon dioxide (CO2) (72% of total...

  15. 3,5-Dichlorophenol Removal From Wastewater Using Alternative Adsorbents

    Science.gov (United States)

    Kobetičová, Hana; Lipovský, Marek; Wachter, Igor; Soldán, Maroš

    2015-06-01

    The main objective of this paper is to evaluate the efficiency of 3,5-dichlorophenol removal from wastewater by using alternative low cost adsorbents. Waste from the production and processing of metals (black nickel mud, red mud) and a biosorbent (Lemna minor) were used for this research. Initial concentration of the contaminant was 4 mmol L-1, the contact time of sorbent and waste water was 0 - 48 hrs and the temperature during experiment was 25 ± 0.2 °C. The results show that the highest removal efficiency of 3,5 - dichlorophenol (58.18 %) was reached by the red mud in 48 hours.

  16. 3,5-Dichlorophenol Removal From Wastewater Using Alternative Adsorbents

    Directory of Open Access Journals (Sweden)

    Kobetičová Hana

    2015-06-01

    Full Text Available The main objective of this paper is to evaluate the efficiency of 3,5-dichlorophenol removal from wastewater by using alternative low cost adsorbents. Waste from the production and processing of metals (black nickel mud, red mud and a biosorbent (Lemna minor were used for this research. Initial concentration of the contaminant was 4 mmol L−1, the contact time of sorbent and waste water was 0 - 48 hrs and the temperature during experiment was 25 ± 0.2 °C. The results show that the highest removal efficiency of 3,5 - dichlorophenol (58.18 % was reached by the red mud in 48 hours.

  17. Synthesis and Insecticidal Activities of 1,3,5-Trisubstituted- 1,3,5-hexahydrotriazine-2-N-nitroimines%Synthesis and Insecticidal Activities of 1,3,5-Trisubstituted- 1,3,5-hexahydrotriazine-2-N-nitroimines

    Institute of Scientific and Technical Information of China (English)

    薛思佳; 马旭波; 步洪飞; 刘丽; 许效

    2011-01-01

    A new series of 1,3,5-trisubstituted-l,3,5-hexahydrotriazine-2-N-nitroimines (3a--3j) were designed and synthesized as novel neonicotinoid analogues, and their structures were characterized by 1H NMR, IR, elemental analysis and MS. The preliminary bioassay tests showed that most of the target compounds had good insecticidal activities against Nilaparvata lugens as well as Aphis medicaginis at 500 mg/L, while compound 3i had 100% mortality against Nilaparvata lugens at 20 mg/L.

  18. Mutational analysis of the respiratory nitrate transporter NarK2 of Mycobacterium tuberculosis.

    Directory of Open Access Journals (Sweden)

    Michelle M Giffin

    Full Text Available Mycobacterium tuberculosis induces nitrate reductase activity in response to decreasing oxygen levels. This is due to regulation of both the transcription and the activity of the nitrate transporter NarK2. A model of NarK2 structure is proposed containing 12 membrane spanning regions consistent with other members of the major facilitator superfamily. The role of the proton gradient was determined by exposing M. tuberculosis to uncouplers. Nitrite production decreased indicating that the importation of nitrate involved an H(+/nitrate symporter. The addition of nitrite before nitrate had no effect, suggesting no role for a nitrate/nitrite antiporter. In addition the NarK2 knockout mutant showed no defect in nitrite export. NarK2 is proposed to be a Type I H(+/nitrate symporter. Site directed mutagenesis was performed changing 23 amino acids of NarK2. This allowed the identification of important regions and amino acids of this transporter. Five of these mutants were inactive for nitrate transport, seven produced reduced activity and eleven mutants retained wild type activity. NarK2 is inactivated in the presence of oxygen by an unknown mechanism. However none of the mutants, including those with mutated cysteines, were altered in their response to oxygen levels. The assimilatory nitrate transporter NasA of Bacillus subtilis was expressed in the M. tuberculosis NarK2 mutant. It remained active during aerobic incubation showing that the point of oxygen control is NarK2.

  19. Studies of Quantum Chemistry of Structure and Properties of 3,7-Bis (nitroimino)-2,4,6,8-tetranitro-2,4,6,8-tetraazabicyclo [3.3.0] octane%3,7-二硝亚胺基-2,4,6,8-四硝基-2,4,6,8-四氮杂双环[3.3.0]辛烷结构与性能的量子化学研究

    Institute of Scientific and Technical Information of China (English)

    金兴辉; 胡炳成; 贾欢庆; 吕春绪

    2013-01-01

    A novel high energetic density compound of 3,7-bis (nitroimino)-2,4,6,8-tetranitro-2,4,6,8-tetraazabicyclo[3.3.0] octane (HNGG) was designed.The stable geometry of the compound was completely optimized at the B3 LYP/6-31 G (d,p) theoretical level of density functional theory (DFT) and the IR spectrum was obtained.The bond dissociation energy(BDE) of the thermolysis initiation bond N7-N22 was calculated and BDE value was 91.47 kJ/mol.The heat of formation of 1219.94 kJ/mol and theoretical density of 2.16g/cm3 were obtained via isodesmic reaction and Monte-Carlo method,respectively.Based on the theoretical density,the formula of Kamlet-Jacobs was used to predict the detonation properties.The results show that HNGG meets the requirements of high energetic materials with detonation velocity of 10.43 km/s,detonation pressure of 53.44 GPa and detonation heat of 7407.84 J/g.In addition,synthetic route of HNGG was also designed.%设计了一种新型高能量密度化合物——3,7-二硝亚胺基-2,4,6,8-四硝基-2,4,6,8-四氮杂双环[3.3.0]辛烷,应用密度泛函理论(DFT)的B3LYP方法在6-31G(d,p)基组水平上对该化合物进行了结构全优化,并计算得到其红外(IR)光谱;通过键级分析获得热解引发键的位置为N7-N22,同时求得校正后的键离解能为91.47 kJ/mol.采用Monte-Carlo方法预测该化合物的理论密度为2.16 g/cm3;基于理论密度并结合等键反应及Kamlet-Jacobs公式预测了生成焓、爆速、爆压和爆热值分别为1219.94 kJ/mol,10.43 km/s,53.44 GPa和7407.84 J/g.以上性能参数显示,该目标化合物达到了高能量密度化合物的基本要求,是一种潜在的含能材料.同时给出了该化合物的逆合成路线.

  20. Coseismic source model of the 2003 Mw 6.8 Chengkung earthquake, Taiwan, determined from GPS measurements

    Science.gov (United States)

    Ching, K.-E.; Rau, R.-J.; Zeng, Y.

    2007-01-01

    A coseismic source model of the 2003 Mw 6.8 Chengkung, Taiwan, earthquake was well determined with 213 GPS stations, providing a unique opportunity to study the characteristics of coseismic displacements of a high-angle buried reverse fault. Horizontal coseismic displacements show fault-normal shortening across the fault trace. Displacements on the hanging wall reveal fault-parallel and fault-normal lengthening. The largest horizontal and vertical GPS displacements reached 153 and 302 mm, respectively, in the middle part of the network. Fault geometry and slip distribution were determined by inverting GPS data using a three-dimensional (3-D) layered-elastic dislocation model. The slip is mainly concentrated within a 44 ?? 14 km slip patch centered at 15 km depth with peak amplitude of 126.6 cm. Results from 3-D forward-elastic model tests indicate that the dome-shaped folding on the hanging wall is reproduced with fault dips greater than 40??. Compared with the rupture area and average slip from slow slip earthquakes and a compilation of finite source models of 18 earthquakes, the Chengkung earthquake generated a larger rupture area and a lower stress drop, suggesting lower than average friction. Hence the Chengkung earthquake seems to be a transitional example between regular and slow slip earthquakes. The coseismic source model of this event indicates that the Chihshang fault is divided into a creeping segment in the north and the locked segment in the south. An average recurrence interval of 50 years for a magnitude 6.8 earthquake was estimated for the southern fault segment. Copyright 2007 by the American Geophysical Union.

  1. Radioimmunoassay for 3,5-diiodothyronine and evidence for dependence on conversion from 3,5,3'-triiodothyronine

    Energy Technology Data Exchange (ETDEWEB)

    Pangaro, L.; Burman, K.D.; Wartofsky, L.; Cahnmann, H.J.; Smallridge, R.C.; O' Brian, J.T.; Wright, F.D.; Latham, K.

    1980-06-01

    The present report describes a RIA for 3,5-diiodothyronine (3,5T/sub 2/) which uses inner ring-labeled 3,5-(/sup 125/I)T/sub 2/ as the ligand and has a lower limit of detectability of 0.5 ng/dl. Cross-reaction was 0.14% with T/sub 3/, less than 0.001% with T/sub 4/, 1.2% with 3,3',5-triiodothyroacetic acid, and 6.1% with 3,5-diiodothyroacetic acid. No cross-reaction was detectable for iodothyronines within their physiological ranges. Intraassay variation ranged from 2.2 to 7.8%, and interassay variation ranged from 12.7 to 14%. The mean (+-SE) serum 3.5T/sub 2/ concentration in 70 normal subjects was 4.3 +- 0.2 ng/dl. The mean (+-SE) 3.5T/sub 2/ in 14 hyperthyroid patients was increased to 18.4 +- 2.3 ng/dl (P < 0.001), and all but 1 patient had an elevated level. In 10 hypothyroid patients the mean (+-SE) 3,5T/sub 2/ level was decreased to 1.4 +- 0.3 ng/dl (P < 0.001). In 4 patients, levels overlapped with the normal range. In 4 hypothyroid subjects treated with L-T/sub 1/, 3,5T/sub 2/ levels were normal, suggesting that the majority of 3,5T/sub 2/ originates from extrathyroidal conversion from T/sub 3/. Studies in fasting obese subjects demonstrated that serum 3,5T/sub 2/ (mean +- SE) levels fell from 3.4 +- 0.3 to 2.5 +- 0.7 ng/dl during fasting. This fall was significant (P < 0.001) and in parallel with the fall in T/sub 3/ levels of 182 +- 20 to 126 +- 12 ng/dl. In fasting subjects given 100 ..mu..g oral L-T/sub 3//day T/sub 3/ levels rose from 138 +- 11 to 362 +- 26 ng/dl. 3,5T/sub 2/ levels (corrected for cross-reaction and for contamination of oral T/sub 3/ with 3,5T/sub 2/) rose from 2.2 +- 0.7 to 6.4 +- 1.0 ng/dl. In fasting subjects given 25 ..mu..g oral L-T/sub 3//day, T/sub 3/ levels fell from 165 +- 5.1 to 139 +- 6.9 ng/dl. Corrected 3,5T/sub 2/ levels changed from 3.7 +- 0.4 to 2.5 +- 0.3 ng/dl. Neither change were significant.

  2. K2GeSe3的中温固相合成%Solid State Synthesis of K2GeSe3 at Intermediate Temperature

    Institute of Scientific and Technical Information of China (English)

    靳星瑞; 张丽丹; 舒桂明; 郭洪猷

    2002-01-01

    采用反应性熔盐法,K2Se4、Ge和Se粉以2∶1∶3的摩尔比在500℃下反应7d, 生成黄色片状晶体K2GeSe3.对产物晶体的热稳定性进行研究,并对其晶体结构和合成方法进行了探讨.

  3. Time course study of oxidative and nitrosative stress and antioxidant enzymes in K2Cr2O7-induced nephrotoxicity

    Directory of Open Access Journals (Sweden)

    Saldívar Liliana

    2005-04-01

    Full Text Available Abstract Background Potassium dichromate (K2Cr2O7-induced nephrotoxicity is associated with oxidative and nitrosative stress. In this study we investigated the relation between the time course of the oxidative and nitrosative stress with kidney damage and alterations in the following antioxidant enzymes: Cu, Zn superoxide dismutase (Cu, Zn-SOD, Mn-SOD, glutathione peroxidase (GPx, glutathione reductase (GR, and catalase (CAT. Methods Nephrotoxicity was induced in rats by a single injection of K2Cr2O7. Groups of animals were sacrificed on days 1,2,3,4,6,8,10, and 12. Nephrotoxicity was evaluated by histological studies and by measuring creatinine clearance, serum creatinine, blood urea nitrogen (BUN, and urinary excretion of N-acetyl-β-D-glucosaminidase (NAG and total protein. Oxidative and nitrosative stress were measured by immunohistochemical localization of protein carbonyls and 3-nitrotyrosine, respectively. Cu, Zn-SOD, Mn-SOD, and CAT were studied by immunohistochemical localization. The activity of total SOD, CAT, GPx, and GR was also measured as well as serum and kidney content of chromium and urinary excretion of NO2 -/NO3-. Data were compared by two-way analysis of variance followed by a post hoc test. Results Serum and kidney chromium content increased reaching the highest value on day 1. Nephrotoxicity was made evident by the decrease in creatinine clearance (days 1–4 and by the increase in serum creatinine (days 1–4, BUN (days 1–6, urinary excretion of NAG (days 1–4, and total protein (day 1–6 and by the structural damage to the proximal tubules (days 1–6. Oxidative and nitrosative stress were clearly evident on days 1–8. Urinary excretion of NO2-/NO3- decreased on days 2–6. Mn-SOD and Cu, Zn-SOD, estimated by immunohistochemistry, and total SOD activity remained unchanged. Activity of GPx decreased on days 3–12 and those of GR and CAT on days 2–10. Similar findings were observed by immunohistochemistry of CAT

  4. Number & operations task sheets : grades 3-5

    CERN Document Server

    Reed, Nat

    2009-01-01

    For grades 3-5, our Common Core State Standards-based resource meets the number & operations concepts addressed by the NCTM standards and encourages the students to learn and review the concepts in unique ways. Each task sheet is organized around a central problem taken from real-life experiences of the students.

  5. 9 CFR 3.5 - Mobile or traveling housing facilities.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Mobile or traveling housing facilities... Transportation of Dogs and Cats 1 Facilities and Operating Standards § 3.5 Mobile or traveling housing facilities. (a) Heating, cooling, and temperature. Mobile or traveling housing facilities for dogs and cats...

  6. trans-1,2-Bis(3,5-dimethoxyphenylethene

    Directory of Open Access Journals (Sweden)

    Stefanie Ritter

    2009-09-01

    Full Text Available The title compound, C18H20O4, was prepared in high yield from 3,5-dimethoxystyrene via a Ru-catalysed homo-olefin metathesis. Exclusive formation of the E-configurated isomer was observed. Interestingly, one symmetric unit contains two molecules adopting an s-syn-anti and and an all-s-anti conformation.

  7. SYNTHESIS AND PROPERTIES OF POLY-1,3,5-TRIAZINES

    Institute of Scientific and Technical Information of China (English)

    WANG Yulan; LU Fengcai

    1984-01-01

    Two new polytriazines: poly[2-methyl-4, 6-(4,' 4"-diphenylene)-1, 3, 5-triazine] (Ⅰ) and poly[2-phenyl-4, 6-(4', 4"-diphenylene)-1, 3, 5-triazine] (Ⅱ) were synthesized from the solution condensation of biphenyl-4, 4'-diamidine dihydrochloride with acetic anhydride and biphenyl-4, 4'-diamidine with benzaldehyde respectively. These two polymers were characterized by TGA, DTA, elemental analysis and IR spectroscopy. They exhibited good thermal oxidative stability as shown by the fact that the powders of these polymers suffered 5.4 %, 2.4 % weight loss after isothermal aging in air at 300℃ for 200 hours. The decomposition temperature of (Ⅱ) was 583℃ in air and 590℃ in N2. These linear poly-1, 3, 5-triazines were soluble in concentrated sulfuric acid, phosphoric acid and trifluoroacetic acid whereas the crosslinked poly-1, 3, 5-triazines reported in the literature were insoluble and infusible.It is interesting that these polymers can form complexes with metal halides as determined by X-ray photoelectron spectroscopy (XPS). The polymer metal complex (Ⅲ). PdCl2 possesses catalytic activity for hydrogenation.

  8. 基于遗传算法的发夫酵母突变株W6-8产虾青素培养基的优化%Medium optimization to improve astaxanthin production of Xanthophyllomyces dendrorhous mutant W6-8 based on genetic algorithms

    Institute of Scientific and Technical Information of China (English)

    汪文俊; 余龙江; 何璞; 周蓬蓬

    2004-01-01

    运用基于达尔文进化学说和适者生存原理的遗传算法对发夫酵母突变株W6-8产虾青素的培养基进行了优化.用50个实验样本完成了6种培养基成分、50个浓度水平的优化工作,完全实验数为506.实验结果表明遗传算法能够成功地用于该培养基优化,并取得了更好的发酵效果.在最优化培养基(葡萄糖39.8g L-1,酵母浸粉4.08 g L-1,(NH4)2SO4 7.36 g L-1,MgSO4 2 g L-1,K2HPO4 2.04 g L-1,KH2PO4 3.48 g L-1)条件下,虾青素的最高产量为9.855 mg L-1,比优化初始条件下提高了约31%,较之正交实验结果高15.46%,略高于用响应面优化方法得到的结果.在随后的放大培养中采用上述优化培养基虾青素最高产量约为14.753 mg L-1.以上结果表明在培养基优化应用中,遗传算法是一种优于正交设计等方法的优化方法.%Genetic algorithms (GA) based on the principle of mimicing Darwinian evolution and survival of the fittest in a natural environment was used to optimize the medium for astaxanthin production by the mutant strain W6-8 of Xanthophyllomyces dendrorhous. The 50 concentration levels of 6 medium components were optimized within 50 experiments (full experimental plan: 506 experiments). The results showed that GA could be applied in the medium optimization and better results were obtained. By employing optimized medium components (glucose 39.8 g l-1, yeast extract 4.08 g l-1,(NH4) 2SO4 7.36 g l-1, MgSO42 g l-1, K2HPO4 2.04 g l-1 and KH2PO4 3.48 g l-1 ), the highest astaxanthin production was 9. 855 mg l-1, approximately 31% higher than that under the initial conditions, and was approximately 15.46% higher than that by orthogonal array but only slightly higher than that by response surface methodology. In the sequent scale-up experiments, the astaxanthin yield was obtained approximately 14. 753 mg l-1, employing the optimal medium. The results indicated that GA, as an eeriicient method for medium optimization, was superior to

  9. On the Formula of the pn-rank of the K2OF%关于K2OF的pn-rank公式

    Institute of Scientific and Technical Information of China (English)

    朱翠香

    2005-01-01

    使用Browkin的方法,将Browkin关于MilnorK-群K2OF的2-rank公式推广到pn-rank的情况(p为素数,n≥1为自然数),从而得到了代数数域F的pn-rank公式,其中F包含pn-次本原单位根.

  10. Integrable deformations of the $G_{k_1} \\times G_{k_2}/G_{k_1+k_2}$ coset CFTs arXiv

    CERN Document Server

    Sfetsos, Konstantinos

    We study the effective action for the integrable $\\lambda$-deformation of the $G_{k_1} \\times G_{k_2}/G_{k_1+k_2}$ coset CFTs. For unequal levels theses models do not fall into the general discussion of $\\lambda$-deformations of CFTs corresponding to symmetric spaces and have many attractive features. We show that the perturbation is driven by parafermion bilinears and we revisit the derivation of their algebra. We uncover a non-trivial symmetry of these models parametric space, which has not encountered before in the literature. Using field theoretical methods and the effective action we compute the exact in the deformation parameter $\\beta$-function and explicitly demonstrate the existence of a fixed point in the IR corresponding to the $G_{k_1-k_2} \\times G_{k_2}/G_{k_1}$ coset CFTs. The same result is verified using gravitational methods for $G=SU(2)$. We examine various limiting cases previously considered in the literature and found agreement.

  11. Characterization of Bacillus phage-K2 isolated from chungkookjang, a fermented soybean foodstuff.

    Science.gov (United States)

    Kim, Eun Ju; Hong, Jeong Won; Yun, Na-Rae; Lee, Young Nam

    2011-01-01

    An investigation of a virulent Bacillus phage-K2 (named Bp-K2) isolated from chungkookjang (a fermented soybean foodstuff) was made. Bp-K2 differed in infectivity against a number of Bacillus subtilis strains including starter strains of chungkookjang and natto, being more infectious to Bacillus strains isolated from the chungkookjang, but much less active against a natto strain. Bp-K2 is a small DNA phage whose genome size is about 21 kb. Bp-K2 is a tailed bacteriophage with an isometric icosahedral head (50 nm long on the lateral side, 80 nm wide), a long contractile sheath (85-90 nm × 28 nm), a thin tail fiber (80-85 nm long, 10 nm wide), and a basal plate (29 nm long, 47 nm wide) with a number of spikes, but no collar. The details of the structures of Bp-K2 differ from natto phage ϕBN100 as well as other known Bacillus phages such as SPO1-like or ϕ 29-like viruses. These data suggest that Bp-K2 would be a new member of the Myoviridae family of Bacillus bacteriophages.

  12. Spitzer Observations of Exoplanets Discovered with The Kepler K2 Mission

    CERN Document Server

    Beichman, Charles; Werner, Michael; Gorjian, Varoujan; Krick, Jessica; Deck, Katherine; Knutson, Heather; Wong, Ian; Petigura, Erik A; Christiansen, Jessie; Ciardi, David; Greene, Thomas P; Schlieder, Joshua E; Line, Mike; Crossfield, Ian; Howard, Andrew; Sinukoff, Evan

    2016-01-01

    We have used the {\\it Spitzer Space Telescope} to observe two transiting planetary systems orbiting low mass stars discovered in the \\Kepler \\Ktwo mission. The system K2-3 (EPIC 201367065) hosts three planets while EPIC 202083828 (K2-26) hosts a single planet. Observations of all four objects in these two systems confirm and refine the orbital and physical parameters of the planets. The refined orbital information and more precise planet radii possible with \\Spitzer will be critical for future observations of these and other \\Ktwo targets. For K2-3b we find marginally significant evidence for a Transit Timing Variation between the \\Ktwo and \\Spitzer\\ epochs.

  13. Population synthesis of RR Lyrae stars in the original $Kepler$ and $K2$ Fields of View

    CERN Document Server

    Hanyecz, Ottó

    2016-01-01

    It is interesting to ask what fraction of the total available RR Lyrae (RRL) sample that falls in the $Kepler$ and $K2$ Fields of View (FoV) is known or discovered. In order assess the completeness of our sample we compared the known RRL sample in the $Kepler$ and $K2$ fields with synthetic Galactic models. The Catalina Sky Survey RRL sample was used to calibrate our method. We found that a large number of faint RRL stars is missing from $Kepler$ and $K2$ fields.

  14. Higgs at 3.5 seconds into the melody

    CERN Multimedia

    Antonella Del Rosso

    2012-01-01

    Listen to the music… at 3.5 into the recording you will be able to “hear” the sound of the newly discovered boson. That’s the beauty of sonification, a technique that translates dry data into beautiful melodies.   Image edit by Katarina Anthony. Sonification is a computational technique that requires enormous amounts of networking and processing power to produce results. The sonification of data presented on 4 July by the ATLAS collaboration was performed using the pan-European GÉANT network and the Grid infrastructure. The result is a melody that at 3.5 seconds reproduces the bump corresponding to the new particle. “This sonification was carried out on the same grid infrastructure used by researchers to reconstruct their data and plot their graphs,” says Domenico Vicinanza of DANTE, who led the Higgs sonification project, collaborating with Mariapaola Sorrentino of ASTRA Project (Cambridge), who contributed to the sonific...

  15. Synthetic routes to 3(5)-phosphonylated pyrazoles

    Science.gov (United States)

    Goulioukina, N. S.; Makukhin, N. N.; Beletskaya, I. P.

    2016-07-01

    This review comprehensively covers the currently available synthetic routes to 3(5)-phosphonylated pyrazoles. There are demonstrated significant advances in this field over the last 10-15 years caused by the use of the Bestmann-Ohira reagent [as well as (diazomethyl)phosphonates and phosphonylated hydrazonoyl halides] in reactions with diverse dipolarophiles. 1,3-Dipolar cycloaddition of diazo compounds to α,β-unsaturated phosphonates as well as intramolecular heterocyclization of (1-diazoallyl)phosphonates and (3--diazo-1-propenyl)phosphonates are discussed. Synthetic potential of cyclocondensation of organophosphorus 1,3-dielectrophilic compounds with hydrazines is shown. Ways to introduce a phosphonate group into the pyrazole ring are considered. Examples of chemical transformations of 3(5)-phosphonylated pyrazoles are reported. The bibliography includes 88 references.

  16. Number & operations task & drill sheets : grades 3-5

    CERN Document Server

    Reed, Nat

    2011-01-01

    For grades 3-5, our Common Core State Standards-based combined resource meets the number & operations concepts addressed by the NCTM standards and encourages the students to review the concepts in unique ways. The task sheets introduce the mathematical concepts to the students around a central problem taken from real-life experiences, while the drill sheets provide warm-up and timed practice questions for the students to strengthen their procedural proficiency skills.

  17. 3.5 TeV : a good start!

    CERN Multimedia

    2009-01-01

    To the pessimists out there, the 3.5 TeV starting energy of the LHC will be like a half-empty glass. However, the thousands of physicists working at the experiments certainly do not share these feelings. On the contrary, they are as excited as ever since they will be the first to observe what happens to matter in these (still) unprecedented conditions.

  18. Geometry task & drill sheets : grades 3-5

    CERN Document Server

    Rosenberg, Mary

    2011-01-01

    For grades 3-5, our Common Core State Standards-based combined resource meets the geometry concepts addressed by the NCTM standards and encourages the students to review the concepts in unique ways. The task sheets introduce the mathematical concepts to the students around a central problem taken from real-life experiences, while the drill sheets provide warm-up and timed practice questions for the students to strengthen their procedural proficiency skills.

  19. N-LEVEL ARCHITECTURE IN .NET 3.5 FRAMEWORK

    OpenAIRE

    Podgoršek, Marko

    2008-01-01

    In this document we discuss several different types of system architecture, including a concise description of several types of acrhictecture, reasons for migrating systems onto a new architecture, common problems we might encounter and possible solutions. We describe in detail the N-tier architecture including the data, business and presentation tier. The goal of this document is to present an implementation of an N-tier architecture using .NET Framework 3.5 and Visual Studio 2008. We focus...

  20. Delayed myelosuppression with acute exposure to hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and environmental degradation product hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (MNX) in rats.

    Science.gov (United States)

    Jaligama, Sridhar; Kale, Vijay M; Wilbanks, Mitchell S; Perkins, Edward J; Meyer, Sharon A

    2013-02-01

    Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), a widely used munitions compound, and hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (MNX), its N-nitroso product of anaerobic microbial nitroreduction, are contaminants of military sites. Previous studies have shown MNX to be the most acutely toxic among the nitroreduced degradation products of RDX and to cause mild anemia at high dose. The present study compares hematotoxicity with acute oral exposure to MNX with parent RDX. Both RDX and MNX caused a modest decrease in blood hemoglobin and ~50% loss of granulocytes (NOAELs=47 mg/kg) in female Sprague-Dawley rats observed 14 days post-exposure. We explored the possibility that blood cell loss observed after 14 days was delayed in onset because of toxicity to bone marrow (BM) progenitors. RDX and MNX decreased granulocyte/macrophage-colony forming cells (GM-CFCs) at 14, but not 7, days (NOAELs=24 mg/kg). The earliest observed time at which MNX decreased GM-CFCs was 10 days post-exposure. RDX and MNX likewise decreased BM burst-forming units-erythroid (BFU-Es) at 14, but not 7, days. Granulocyte-erythrocyte-monocyte-megakaryocyte (GEMM)-CFCs were unaffected by RDX and MNX at 7 days suggesting precursor depletion did not account for GM-CFC and BFU-E loss. MNX added to the culture media was without effect on GM-CFC formation indicating no direct inhibition. Flow cytometry showed no differential loss of BM multilineage progenitors (Thy1.1(+)) or erythroid (CD71(+)) precursors with MNX suggesting myeloid and erythroid lineages were comparably affected. Collectively, these data indicate that acute exposure to both RDX and MNX caused delayed suppression of myelo- and erythropoiesis with subsequent decrease of peripheral granulocytes and erythrocytes. Copyright © 2012 Elsevier Inc. All rights reserved.

  1. The sizes of $z\\sim6-8$ lensed galaxies from the Hubble Frontier Fields Abell 2744 data

    CERN Document Server

    Kawamata, Ryota; Shimasaku, Kazuhiro; Oguri, Masamune; Ouchi, Masami

    2014-01-01

    We investigate sizes of $z\\sim6-8$ dropout galaxies using the complete data of the Abell 2744 cluster and parallel fields in the Hubble Frontier Fields program. By directly fitting light profiles of observed galaxies with lensing-distorted S\\'ersic profiles on the image plane with the \\texttt{glafic} software, we accurately measure intrinsic sizes of 31 $z\\sim6-7$ and eight $z\\sim8$ galaxies, including those as faint as $M_{\\mathrm{UV}}\\simeq-17$. We find that half-light radii $r_\\mathrm{e}$ positively correlates with UV luminosity at each redshift, although the correlation is not very tight. Largest ($r_\\mathrm{e}>0.8$ kpc) galaxies are mostly red in UV color while smallest ($r_\\mathrm{e} < 0.05$ kpc) ones tend to be blue. We also find that galaxies with multiple cores tend to be brighter. Combined with previous results at $2.5\\lesssim z\\lesssim12$, our result confirms that the average $r_{\\mathrm{e}}$ of bright ($(0.3-1)L^\\star_{z=3}$) galaxies scales as $r_{\\mathrm{e}}\\propto(1+z)^{-m}$ with $m=1.31\\pm0...

  2. Kinetic Requirements for the Measurement of Mesospheric Water Vapor at 6.8 (microns) under Non-LTE Conditions

    Science.gov (United States)

    Zhou, Daniel K.; Mlynczak, Martin G.; Lopez-Puertas, Manuel; Russell, James M., III

    1999-01-01

    We present accuracy requirements for specific kinetic parameters used to calculate the populations and vibrational temperatures of the H2O(010) and H2O(020) states in the terrestrial mesosphere. The requirements are based on rigorous simulations of the retrieval of mesospheric water vapor profiles from measurements of water vapor infrared emission made by limb scanning instruments on orbiting satellites. Major improvements in the rate constants that describe vibration-to- vibration exchange between the H2O(010) and 02(1) states are required in addition to improved specification of the rate of quenching Of O2(1) by atomic oxygen (0). It is also necessary to more accurately determine the yield of vibrationally excited O2(l) resulting from ozone photolysis. A contemporary measurement of the rate of quenching of H2O(010) by N2 and O2 is also desirable. These rates are either highly uncertain or have never before been measured at atmospheric temperatures. The suggested improvements are necessary for the interpretation of water vapor emission measurements at 6.8 microns to be made from a new spaceflight experiment in less than 2 years. The approach to retrieving water vapor under non-LTE conditions is also presented.

  3. DFT studies on a high energy density cage compound 4-trinitroethyl-2,6,8,10,12-pentanitrohezaazaisowurtzitane.

    Science.gov (United States)

    Zhang, Jian-ying; Du, Hong-chen; Wang, Fang; Gong, Xue-dong; Huang, Yin-sheng

    2011-06-23

    Polynitro cage compound 4-trinitroethyl-2,6,8,10,12-pentanitrohexaazaisowurtzitane has the same framework with but higher stability than CL-20 and is a potential new high energy density compound (HEDC). In this paper, the B3LYP/6-31G(d,p) method of density functional theory (DFT) has been used to study its heat of formation, IR spectrum, and thermodynamic properties. The stability of the compound was evaluated by the bond dissociation energies. The calculated results show that the first step of pyrolysis is the rupture of the N-NO(2) bond in the side chain and verify the experimental observation that the title compound has better stability than CL-20. The crystal structure obtained by molecular mechanics belongs to the P2(1)2(1)2(1) space group, with lattice parameters a = 12.59 Å, b = 10.52 Å, c = 12.89 Å, Z = 4, and ρ = 2.165 g·cm(-3). Both the detonation velocity of 9.767 km·s(-1) and the detonation pressure of 45.191 GPa estimated using the Kamlet-Jacobs equation are better than those of CL-20. Considering that this cage compound has a better detonation performance and stability than CL-20, it may be a superior HEDC.

  4. Solar wind triggering of geomagnetic disturbances and strong (M>6.8) earthquakes during the November - December 2004 period

    CERN Document Server

    Anagnostopoulos, G; Antoniou, P

    2010-01-01

    This paper brings space weather prediction close to earthquake (EQ) prediction research. The results of this paper support conclusions of previously presented statistical studies that solar activity influences the seismic activity, this influence is mediated through rapid geomagnetic disturbances and the geomagnetic disturbances are related with increases of solar wind speed. Our study concern an example of 40 days with direct response of a series of 7 strong-to-giant (M=6.8-9.3) EQs (including the Andaman-Sumatra EQ) to solar wind speed increases and subsequent geomagnetic fast disturbances. Our analysis for 10 M>6 EQs from November 23 to December 28, 2004 suggests a mean time response delay of EQs to fast geomagnetic disturbances of ~1.5 days. The two giant EQs during this period occurred after the two fastest geomagnetic variations, as revealed by the ratio of the daily Kp index variation over a day {\\Delta}Kp/{\\Delta}t (12 and 15, respectively). It suggests that the fast disturbance of the magnetosphere, ...

  5. Differential scanning calorimetry studies of Se85Te15–Pb ( = 4, 6, 8 and 10) glasses

    Indian Academy of Sciences (India)

    N B Maharajan; N S Saxena; Deepika Bhandari; Mousa M Imran; D D Paudyal

    2000-10-01

    Results of differential scanning calorimetry (DSC) studies of Se85Te15–Pb ( = 4, 6, 8 and 10) glasses have been reported and discussed in this paper. The results have been analyzed on the basis of structural relaxation equation, Matusita’s equation and modified Kissinger’s equation. The activation energies of structural relaxation lie in between 226 and 593 kJ/mol. The crystallization growth is found to be onedimensional for all compositions. The activation energies of crystallization are found to be 100–136 kJ/mol by Matusita’s equation while 102–139 kJ/mol by modified Kissinger’s equation. The Hruby number (indicator of ease of glass forming and higher stability) is the highest for Se85Te9Pb6 glass while S factor (indicator of resistance to devitrification) is highest for Se85Te7Pb8 glass at all heating rates in our experiment. Further the highest resistance to devitrification has the highest value of structural activation energy and the activation energy of crystallization is maximum for the most stable glass by both Matusita’s equation and the modified Kissinger’s equation.

  6. A Co(Ⅱ) 3,5-Diaminobenzoate Coordination Polymer

    Institute of Scientific and Technical Information of China (English)

    DAI Yu-Mei; TANG En; LI Zhao-Ji; WANG Xiao-Qin; YIN Pei-Xiu; YAO Yuan-Gen

    2006-01-01

    The title compound, [Co(C7N2H7O2)2]n·nH2O 1, was synthesized via the hydrothermal reaction of Co(Oac)2 with 3,5-diaminobenzoic acid and characterized by elemental analysis and infrared spectra. The crystal crystallizes in the monoclinic system, space group P21/c with a =7.456(3), b = 9.972(3), c = 10.391 (3) (A), β= 106.435(2)°, V = 741.0(4) (A)3, Z = 2, C14H16CoN4O5, Mr = 379.24, Dc = 1.700 g/cm3, F(000) = 390 and μ(MoKa) = 1.194 mm-1. The final R = 0.0324 and wR = 0.0886 for 1516 observed reflections with I>2σ(I) and R = 0.0337 and wR = 0.0899 for all data. X-ray diffraction studies reveal that the title compound has an interesting 3D microporous architecture with guest water molecules inside the channel. Each Co atom, adopting a distorted octahedral geometry, is coordinated by two O atoms from two 3,5-diaminobenzoate ligands and four N atoms from four symmetry-related 3,5-diaminobenzoate ligands.

  7. Preliminary evaluation of the role of K2S in MHD hot stream seed recovery

    Science.gov (United States)

    Bennett, J. E.; Kohl, F. J.

    1979-01-01

    Results are presented for recent analytical and experimental studies of the role of K2S in MHD hot stream seed recovery. The existing thermodynamic data base was found to contain large uncertainties and to be nonexistent for vapor phase K2S. Knudsen cell mass spectrometric experiments were undertaken to determine the vapor species in equilibrium with K2S(c). K atoms and S2 molecules ere found to be the major vapor phase species in vacuum, accounting for greater than 99 percent of the vapor phase. Combustion gas deposition studies using No. 2 Diesel fuel were also undertaken and revealed that condensed phase K2SO3 may potentially be an important compound in the MHD stream at near-stoichiometric combustion.

  8. [Vitamin K2 as a protector of bone health and beyond].

    Science.gov (United States)

    Kaneki, Masao

    2005-04-01

    Several lives of evidence indicate a protective effect of vitamin K against osteoporosis. Epidemiological studies showed that low vitamin K intake is associated with the increased risk of osteoporosis. Vitamin K2 (menatetrenone, MK-4) has been clinically used in the treatment of patients with osteoporosis in Japan, Korea and Thailand. Previous studies demonstrated the efficacy of vitamin K2 (45 mg/day) to prevent bone loss and reduce the rate of vertebral fractures, although a large, randomized intervention study is anticipated to provide more detailed evidence. Recently, vitamin K2 has been shown to reduce the progression of hepatocarcinoma. Moreover, it has been proposed that vitamin K may also have beneficial effects to prevent atherogenesis. The clarification of molecular mechanisms by which vitamin K2 exerts these salutary effects deserve further investigations.

  9. Experimental study on NO oxidation by K2S2O8 + Fe(II)EDTA

    Science.gov (United States)

    Hu, Hui; Huang, Hao; Tao, Gong-Kai; Xie, Jing; Yang, Cheng; Huang, Ting

    2017-06-01

    NO absorption and oxidation by K2S2O8 + Fe(II)EDTA system was studied in a lab-scale bubble reactor. The effects of different additives, reaction temperatures, pH values, K2S2O8 and Fe(II)EDTA concentrations on NO conversion were systematic investigated. Results indicated that NO conversion rate of K2S2O8 + Fe(II)EDTA system increased to 91.6% when concentrations of K2S2O8 and Fe(II)EDTA were both 30 mmol/L at 80 °C. NO conversion rate was positively correlated with the SO42- concentration in absorption solution, and it kept around 80% in a wide pH range, which made this technology to be a promising method for the denitrification of coal-fired flue gas.

  10. Data of evolutionary structure change: 1AW2K-2VENA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1AW2K-2VENA 1AW2 2VEN K A --RHPVVMGNWKLNGSKEMVVDLLNGLNAELEGVTGVDV...RQLDAVINTQGVEALEGAIIAYEPIWAIGTGKAATAEDAQRIHAQIRAHIAEK-SEAVAKNVVIQYGGSVKPENAAAYFAQPDIDGALVGGAALDAKSFAAIAKAAAE...ine> 2VEN A 2VENA1 2VEN A 2VENA A 2VENA YEPVW-----KVATP

  11. Preparation and characterization of keratin-K2Ti6O13 whisker ...

    African Journals Online (AJOL)

    USER

    2010-05-10

    May 10, 2010 ... hexatitanate (K2Ti6O13) whiskers be used to reinforce keratin film. The effects of ... reinforced composite manufacturing Co., and the optical micrograph is .... on the mechanical properties of jute-polypropylene composites.

  12. A conjecture on a class of elements of finite order in K2Fp

    Institute of Scientific and Technical Information of China (English)

    XU; Kejian

    2001-01-01

    [1] Tate, J., Relation between K2 and Galois cohomology, Invent. Math., 1976, 36: 257.[2] Suslin, A. A., Torsion in K2 of fields, K-Theory, 1987, 1: 5.[3] Moore, C., Group extensions of p-adic and adelic linear groups, Publ. Math. I .H. E. S., 1969, 35: 5.[4] Carroll, J. E., On the torsion in K2 of local fields, Lecture Notes in Math., Vol. 342, Berlin: Springer-Verlag, 1973, 464.[5] Tate, J., On the torsion in K2 of fields, Algebraic Number Theory, papers contributed for the International symposium, Kyoto 1976, 243.[6] Merkurjev, A. S., On the torsion in K2 of local fields, Annals of Mathematics, 1983, 118: 375.[7] Browkin, J., Elements of small order in K2F, Algebraic K-Theory, Lecture Notes in Math., Vol. 966, Berlin-Heidelberg-New York: Springer-Verlag, 1982, 1-6.[8] Urbanowicz, J., On elements of given orders in K2F, J. Pure. Appl. Alg., 1988, 50: 295.[9] Qin Hourong, Elements of finite order in K2F of fields, Chinese Science Bulletin, 1994, 38(24): 2227.[10] Qin Hourong, The 2-Sylow subgroups of K2OF for real quadratic fields F, Science in China (in Chinese), Ser. A, 1993, 23(12): 1254.[11] Qin Hourong, The 2-Sylow subgroups of the tame kernel of imagine quadratic fields, Acta Arith., 1995, 69: 153.[12] Qin Hourong, The 4-rank of K2OF for real quadratic fields, Acta Arith., 1995, 72: 323.[13] Qin Hourong, The subgroups of finite order in K2Q, Algebraic K-Theory and Its Application (eds. Bass, H., Kuku, A. O., Pedrini, C.), Singapore: World Scientific, 1999, 600-607.[14] Weiss, E., Algebraic Number Theory, New York: McGraw-Hill, 1963, 119-120, 185-186.[15] Iwasawa, K., Local Class Field Theory (in Chinese), Beijing: Science Press, 1986, 27-28, 129-130.[16] Neukirch, J., Class Field Theory, Berlin-Heidelberg: Springer-Verlag, 1986, 50.

  13. Time-Series Analysis of Broadband Photometry of Neptune from K2

    DEFF Research Database (Denmark)

    Rowe, Jason F.; Gaulme, Patrick; Lissauer, Jack J.

    2017-01-01

    We report here on our search for excess power in photometry of Neptune collected by the K2 mission that may be due to intrinsic global oscillations of the planet Neptune. To conduct this search, we developed new methods to correct for instrumental effects such as intrapixel variability and gain...... and the K2 spacecraft, and solar variability with convection-driven solar p modes present....

  14. 2-Sylow Subgroups of K2OF for Real Quadratic Fields F

    Institute of Scientific and Technical Information of China (English)

    秦厚荣

    1994-01-01

    A method which can be used to determine the structures of 2-Sylow subgroups of K2OF for real quadratic fields F is given.By this method,the structures of the 2-Sylow subgroups of K2OF for some real quadratic fields are determined.The method here is suitable for the non-elementary Abelian case as well as the elementary Abelian case.

  15. The longstanding challenge of the nanocrystallization of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX

    Directory of Open Access Journals (Sweden)

    Florent Pessina

    2017-02-01

    Full Text Available Research efforts for realizing safer and higher performance energetic materials are continuing unabated all over the globe. While the thermites – pyrotechnic compositions of an oxide and a metal – have been finely tailored thanks to progress in other sectors, organic high explosives are still stagnating. The most symptomatic example is the longstanding challenge of the nanocrystallization of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX. Recent advances in crystallization processes and milling technology mark the beginning of a new area which will hopefully lead the pyroelectric industry to finally embrace nanotechnology. This work reviews the previous and current techniques used to crystallize RDX at a submicrometer scale or smaller. Several key points are highlighted then discussed, such as the smallest particle size and its morphology, and the scale-up capacity and the versatility of the process.

  16. Lateral Transfer of Genes for Hexahydro-1,3,5-Trinitro-1,3,5-Triazine (RDX) Degradation▿ †

    Science.gov (United States)

    Andeer, Peter F.; Stahl, David A.; Bruce, Neil C.; Strand, Stuart E.

    2009-01-01

    Recent studies demonstrated that degradation of the military explosive hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) by species of Rhodococcus, Gordonia, and Williamsia is mediated by a novel cytochrome P450 with a fused flavodoxin reductase domain (XplA) in conjunction with a flavodoxin reductase (XplB). Pulse field gel analysis was used to localize xplA to extrachromosomal elements in a Rhodococcus sp. and distantly related Microbacterium sp. strain MA1. Comparison of Rhodococcus rhodochrous 11Y and Microbacterium plasmid sequences in the vicinity of xplB and xplA showed near identity (6,710 of 6,721 bp). Sequencing of the associated 52.2-kb region of the Microbacterium plasmid pMA1 revealed flanking insertion sequence elements and additional genes implicated in RDX uptake and degradation. PMID:19270122

  17. The longstanding challenge of the nanocrystallization of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX)

    Science.gov (United States)

    Spitzer, Denis

    2017-01-01

    Research efforts for realizing safer and higher performance energetic materials are continuing unabated all over the globe. While the thermites – pyrotechnic compositions of an oxide and a metal – have been finely tailored thanks to progress in other sectors, organic high explosives are still stagnating. The most symptomatic example is the longstanding challenge of the nanocrystallization of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX). Recent advances in crystallization processes and milling technology mark the beginning of a new area which will hopefully lead the pyroelectric industry to finally embrace nanotechnology. This work reviews the previous and current techniques used to crystallize RDX at a submicrometer scale or smaller. Several key points are highlighted then discussed, such as the smallest particle size and its morphology, and the scale-up capacity and the versatility of the process. PMID:28326236

  18. Enhancement of CO2 sorption uptake on hydrotalcite by impregnation with K2CO3.

    Science.gov (United States)

    Lee, Jung Moo; Min, Yoon Jae; Lee, Ki Bong; Jeon, Sang Goo; Na, Jeong Geol; Ryu, Ho Jung

    2010-12-21

    The awareness of symptoms of global warming and its seriousness urges the development of technologies to reduce greenhouse gas emissions. Carbon dioxide (CO(2)) is a representative greenhouse gas, and numerous methods to capture and storage CO(2) have been considered. Recently, the technology to remove high-temperature CO(2) by sorption has received lots of attention. In this study, hydrotalcite, which has been known to have CO(2) sorption capability at high temperature, was impregnated with K(2)CO(3) to enhance CO(2) sorption uptake, and the mechanism of CO(2) sorption enhancement on K(2)CO(3)-promoted hydrotalcite was investigated. Thermogravimetric analysis was used to measure equilibrium CO(2) sorption uptake and to estimate CO(2) sorption kinetics. The analyses based on N(2) gas physisorption, X-ray diffractometry, Fourier transform infrared spectrometry, Raman spectrometry, transmission electron microscopy, scanning electron microscopy, and energy dispersive X-ray spectroscopy were carried out to elucidate the characteristics of sorbents and the mechanism of enhanced CO(2) sorption. The equilibrium CO(2) sorption uptake on hydrotalcite could be increased up to 10 times by impregnation with K(2)CO(3), and there was an optimal amount of K(2)CO(3) for a maximum equilibrium CO(2) sorption uptake. In the K(2)CO(3)-promoted hydrotalcite, K(2)CO(3) was incorporated without changing the structure of hydrotalcite and it was thermally stabilized, resulting in the enhanced equilibrium CO(2) sorption uptake and fast CO(2) sorption kinetics.

  19. K2 killer toxin-induced physiological changes in the yeast Saccharomyces cerevisiae.

    Science.gov (United States)

    Orentaite, Irma; Poranen, Minna M; Oksanen, Hanna M; Daugelavicius, Rimantas; Bamford, Dennis H

    2016-03-01

    Saccharomyces cerevisiae cells produce killer toxins, such as K1, K2 and K28, that can modulate the growth of other yeasts giving advantage for the killer strains. Here we focused on the physiological changes induced by K2 toxin on a non-toxin-producing yeast strain as well as K1, K2 and K28 killer strains. Potentiometric measurements were adjusted to observe that K2 toxin immediately acts on the sensitive cells leading to membrane permeability. This correlated with reduced respiration activity, lowered intracellular ATP content and decrease in cell viability. However, we did not detect any significant ATP leakage from the cells treated by killer toxin K2. Strains producing heterologous toxins K1 and K28 were less sensitive to K2 than the non-toxin producing one suggesting partial cross-protection between the different killer systems. This phenomenon may be connected to the observed differences in respiratory activities of the killer strains and the non-toxin-producing strain at low pH. This might also have practical consequences in wine industry; both as beneficial ones in controlling contaminating yeasts and non-beneficial ones causing sluggish fermentation. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. Physical activity, diet and BMI in children aged 6-8 years: a cross-sectional analysis.

    Science.gov (United States)

    Basterfield, Laura; Jones, Angela R; Parkinson, Kathryn N; Reilly, Jessica; Pearce, Mark S; Reilly, John J; Adamson, Ashley J

    2014-06-05

    To assess relationships between current physical activity (PA), dietary intake and body mass index (BMI) in English children. Longitudinal birth cohort study in northeast England, cross-sectional analysis. 425 children (41% of the original cohort) aged 6-8 years (49% boys). PA over 7 days was measured objectively by an accelerometer; three categories of PA were created: 'active' ≥60 min/day moderate-to-vigorous-intensity PA (MVPA); 'moderately active' 30-59 min/day MVPA; 'inactive' Children were classified as 'healthy weight' or 'overweight or obese' (OW/OB) according to International Obesity Taskforce cutpoints for BMI. Associations between weight status and PA/diet categories were analysed using logistic regression. Few children met the UK-recommended guidelines for either MVPA or fruit and vegetable intake, with just 7% meeting the recommended amount of MVPA of 60 min/day, and 3% meeting the 5-a-day fruit and vegetable recommendation. Higher PA was associated with a lower OR for OW/OB in boys only (0.20, 95% CI 0.04 to 0.88). There was no association detected between dietary intake and OW/OB in either sex. Increasing MVPA may help to reduce OW/OB in boys; however, more research is required to examine this relationship in girls. Children are not meeting the UK guidelines for diet and PA, and more needs to be done to improve this situation. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  1. Comorbidity and correlates of disruptive mood dysregulation disorder in 6-8-year-old children with ADHD.

    Science.gov (United States)

    Mulraney, Melissa; Schilpzand, Elizabeth J; Hazell, Philip; Nicholson, Jan M; Anderson, Vicki; Efron, Daryl; Silk, Timothy J; Sciberras, Emma

    2016-03-01

    This study aimed to characterize the nature and impact of disruptive mood dysregulation disorder (DMDD) in children with attention-deficit/hyperactivity disorder (ADHD) including its co-occurrence with other comorbidities and its independent influence on daily functioning. Children with ADHD (6-8 years) were recruited through 43 Melbourne schools, using a 2-stage screening (parent and teacher Conners 3 ADHD index) and case-confirmation (Diagnostic Interview Schedule for Children, Version IV; [DISC-IV]) procedure. Proxy DMDD diagnosis was confirmed via items from the oppositional defiant disorder (ODD) and major depressive disorder modules of the DISC-IV. Outcome domains included comorbid mental health disorders, academic functioning, social functioning, child and family quality of life, parent mental health, and parenting behaviors. Unadjusted and adjusted linear and logistic regression were used to compare children with comorbid ADHD and DMDD and children with ADHD without DMDD. Thirty-nine out of 179 children (21.8 %) with ADHD had comorbid DMDD. Children with ADHD and DMDD had a high prevalence of ODD (89.7 %) and any anxiety disorder (41.0 %). Children with ADHD and DMDD had poorer self-control and elevated bullying behaviors than children with ADHD without DMDD. Children with ADHD and DMDD were similar to children with ADHD in the other domains measured when taking into account other comorbidities including ODD. One in five children with ADHD in their second year of formal schooling met criteria for DMDD. There was a very high diagnostic overlap with ODD; however, the use of a proxy DMDD diagnosis containing items from the ODD module of the DISC-IV may have artificially inflated the comorbidity rates. DMDD added to the burden of ADHD particularly in the area of social functioning.

  2. Evolution of a physiological pH 6.8 bicarbonate buffer system: application to the dissolution testing of enteric coated products.

    OpenAIRE

    Liu, Fang; Merchant, Hamid A.; Kulkarni, Rucha P.; Alkademi, Maram; Basit, Abdul W

    2011-01-01

    The use of compendial pH 6.8 phosphate buffer to assess dissolution of enteric coated products gives rise to poor in vitro-in vivo correlations because of the inadequacy of the buffer to resemble small intestinal fluids. A more representative and physiological medium, pH 6.8 bicarbonate buffer, was developed to evaluate the dissolution behaviour of enteric coatings. The bicarbonate system was evolved from pH7.4 Hanks balanced salt solution to produce a pH 6.8 bicarbonate buffer (modified Hank...

  3. Research progress of vitamin K2 and osteoporosis%维生素K2与骨质疏松症的研究进展

    Institute of Scientific and Technical Information of China (English)

    王强; 王声雨; 顾群; 陶树清; 陶天遵; 荣杰生

    2013-01-01

    With the acceleration of aging process in human society, the number of osteoporosis patients is increasing day by day. By now osteoporosis has become a serious threat to the health of middle and old aged people. Vitamin K, also known as blood coagulation vitamin, plays a role in many aspects of the bone metabolism, including bone formation, bone resorption, increasing bone strength, improving bone quality, and reducing the risk of osteoporotic fractures. It is effective in the treatment of osteoporosis caused by a variety of factors. Because of few side effects, low toxicity and beneifcial effects, more and more attention has been paid to vitamin K2. The recent research progress of vitamin K2 and osteoporosis is reviewed in this article.

  4. K2 Variable Catalogue II: Machine Learning Classification of Variable Stars and Eclipsing Binaries in K2 Fields 0-4

    CERN Document Server

    Armstrong, D J; Lam, K W F; McCormac, J; Osborn, H P; Spake, J; Walker, S; Brown, D J A; Kristiansen, M H; Pollacco, D; West, R; Wheatley, P J

    2015-01-01

    We are entering an era of unprecedented quantities of data from current and planned survey telescopes. To maximise the potential of such surveys, automated data analysis techniques are required. Here we implement a new methodology for variable star classification, through the combination of Kohonen Self Organising Maps (SOM, an unsupervised machine learning algorithm) and the more common Random Forest (RF) supervised machine learning technique. We apply this method to data from the K2 mission fields 0-4, finding 154 ab-type RR Lyraes (15 newly discovered), 377 Delta Scuti pulsators, 133 Gamma Doradus pulsators, 183 detached eclipsing binaries, 290 semi-detached or contact eclipsing binaries and 9399 other periodic (mostly spot-modulated) sources, once class significance cuts are taken into account. We present lightcurve features for all K2 stellar targets, including their three strongest detected frequencies, which can be used to study stellar rotation periods where the observed variability arises from spot m...

  5. The boundary RSOS \\mathcal{M}(3,5) model

    CERN Document Server

    Deeb, Omar El

    2015-01-01

    We consider the critical non-unitary minimal model {\\cal M}(3,5) with integrable boundaries. We analyze the patterns of zeros of the eigenvalues of the transfer matrix and then determine the spectrum of the critical theory through the Thermodynamic Bethe Ansatz (TBA) equations. We derive these equations for all excitations by solving, the TBA functional equation satisfied by the transfer matrices of the associated A_{4} RSOS lattice model of Forrester and Baxter in Regime III, then determine their corresponding energies. The excitations are classified in terms of (m,n) systems.

  6. Delayed myelosuppression with acute exposure to hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and environmental degradation product hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (MNX) in rats

    Energy Technology Data Exchange (ETDEWEB)

    Jaligama, Sridhar; Kale, Vijay M.; Wilbanks, Mitchell S. [Department of Toxicology, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71209 (United States); Perkins, Edward J. [US Army Engineer Research and Development Center, Vicksburg, MS 39180 (United States); Meyer, Sharon A., E-mail: meyer@ulm.edu [Department of Toxicology, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71209 (United States)

    2013-02-01

    Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), a widely used munitions compound, and hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (MNX), its N-nitroso product of anaerobic microbial nitroreduction, are contaminants of military sites. Previous studies have shown MNX to be the most acutely toxic among the nitroreduced degradation products of RDX and to cause mild anemia at high dose. The present study compares hematotoxicity with acute oral exposure to MNX with parent RDX. Both RDX and MNX caused a modest decrease in blood hemoglobin and ∼ 50% loss of granulocytes (NOAELs = 47 mg/kg) in female Sprague–Dawley rats observed 14 days post-exposure. We explored the possibility that blood cell loss observed after 14 days was delayed in onset because of toxicity to bone marrow (BM) progenitors. RDX and MNX decreased granulocyte/macrophage-colony forming cells (GM-CFCs) at 14, but not 7, days (NOAELs = 24 mg/kg). The earliest observed time at which MNX decreased GM-CFCs was 10 days post-exposure. RDX and MNX likewise decreased BM burst-forming units-erythroid (BFU-Es) at 14, but not 7, days. Granulocyte–erythrocyte–monocyte–megakaryocyte (GEMM)-CFCs were unaffected by RDX and MNX at 7 days suggesting precursor depletion did not account for GM-CFC and BFU-E loss. MNX added to the culture media was without effect on GM-CFC formation indicating no direct inhibition. Flow cytometry showed no differential loss of BM multilineage progenitors (Thy1.1{sup +}) or erythroid (CD71{sup +}) precursors with MNX suggesting myeloid and erythroid lineages were comparably affected. Collectively, these data indicate that acute exposure to both RDX and MNX caused delayed suppression of myelo- and erythropoiesis with subsequent decrease of peripheral granulocytes and erythrocytes. Highlights: ► Acute oral exposure to munitions RDX causes myelosuppression. ► Environmental degradation product MNX is comparable in effect. ► RDX and MNX are cytotoxic to both myeloid and erythroid

  7. 3'-5' RNA degradation pathways in human cells

    DEFF Research Database (Denmark)

    Lubas, Michal Szymon

    RNA synthesis and degradation are key steps in the regulation of gene expression in all living organisms. During the course of his PhD studies, Michal Lubas centred his research on the nuclear and cytoplasmic RNA turnover of both noncoding and coding RNAs in human cells. His proteomic studies...... of the cytoplasmic 3'-5' exoribonuclease hDIS3L2. Using low throughout and high throughput techniques, both in vivo and in vitro, he characterised the nuclease and disclosed the role of hDIS3L2 in cytoplasmic mRNA metabolism....

  8. Removing 3,5-Dichlorophenol from Wastewater by Alternative Adsorbents

    Directory of Open Access Journals (Sweden)

    Kobetičová Hana

    2014-12-01

    Full Text Available The main objective of this paper is to evaluate an efficiency of 3,5 - dichlorophenol removal from wastewater by using alternative adsorbents. Chlorophenols are organic compounds consisting of a benzene ring, OH groups and also atoms of chlorine. Chlorophenols may have a huge isomere variety that means there are differences in their chemical and physical properties. Due to their toxicity it is necessary to remove them from waste water and in this paper an alternative way of such process is described.

  9. A PSF-based approach to Kepler/K2 data. I. Variability within the K2 Campaign 0 star clusters M 35 and NGC 2158

    CERN Document Server

    Libralato, M; Nardiello, D; Piotto, G

    2015-01-01

    Kepler and K2 data analysis reported in the literature is mostly based on aperture photometry. Because of Kepler's large, undersampled pixels and the presence of nearby sources, aperture photometry is not always the ideal way to obtain high-precision photometry and, because of this, the data set has not been fully exploited so far. We present a new method that builds on our experience with undersampled HST images. The method involves a point-spread function (PSF) neighbour-subtraction and was specifically developed to exploit the huge potential offered by the K2 "super-stamps" covering the core of dense star clusters. Our test-bed targets were the NGC 2158 and M 35 regions observed during the K2 Campaign 0. We present our PSF modeling and demonstrate that, by using a high-angular-resolution input star list from the Asiago Schmidt telescope as the basis for PSF neighbour subtraction, we are able to reach magnitudes as faint as Kp~24 with a photometric precision of 10% over 6.5 hours, even in the densest region...

  10. Cascade Wittig reaction-double Claisen and Cope rearrangements: one-pot synthesis of diprenylated coumarins gravelliferone, balsamiferone, and 6,8-diprenylumbelliferone

    Digital Repository Service at National Institute of Oceanography (India)

    Patre, R.E.; Shet, J.B.; Parameswaran, P.S.; Tilve, S.G.

    A cascade Wittig reaction-double Claisen and Cope rearrangements has been employed for a one-pot synthesis of diprenylated coumarins gravelliferone, balsamiferone, and 6,8-diprenylumbelliferone from a common precursor 2,4-diprenyloxybenzaldehyde...

  11. Associations between indoor environmental factors and parental-reported autistic spectrum disorders in children 6-8 years of age.

    Science.gov (United States)

    Larsson, Malin; Weiss, Bernard; Janson, Staffan; Sundell, Jan; Bornehag, Carl-Gustav

    2009-09-01

    Potential contributions of environmental chemicals and conditions to the etiology of Autism Spectrum Disorders are the subject of considerable current research and speculation. The present paper describes the results of a study undertaken as part of a larger project devoted to the connection between properties of the indoor environment and asthma and allergy in young Swedish children. The larger project, The Dampness in Buildings and Health (DBH) Study, began in the year 2000 with a questionnaire distributed to parents of all children 1-6 years of age in one Swedish county (DBH-I). A second, follow-up questionnaire (DBH-III) was distributed in 2005. The original survey collected information about the child, the family situation, practices such as smoking, allergic symptoms, type of residence, moisture-related problems, and type of flooring material, which included polyvinyl chloride (PVC). The 2005 survey, based on the same children, now 6-8 years of age, also asked if, during the intervening period, the child had been diagnosed with Autism, Asperger's syndrome, or Tourette's syndrome. From a total of 4779 eligible children, 72 (60 boys, 12 girls) were identified with parentally reported autism spectrum disorder. A random sample of 10 such families confirmed that the diagnoses had been made by medical professionals, in accordance with the Swedish system for monitoring children's health. An analysis of the associations between indoor environmental variables in 2000 as well as other background factors and the ASD diagnosis indicated five statistically significant variables: (1) maternal smoking; (2) male sex; (3) economic problems in the family; (4) condensation on windows, a proxy for low ventilation rate in the home; (5) PVC flooring, especially in the parents' bedroom. In addition, airway symptoms of wheezing and physician-diagnosed asthma in the baseline investigation (2000) were associated with ASD 5 years later. Results from the second phase of the DBH

  12. Chemical stability at noble metal M/YBa 2Cu 3O 6.8 interfaces (M = Pt, Ag, Au)

    Science.gov (United States)

    Bohnenkamp-Weiss, Ruth; Schmid-Fetzer, Rainer

    1994-02-01

    The chemical compatibility between YBa 2Cu 3O 6.8 (Y123) and Pt, Ag or Au was studied using quasi-infinite diffusion couples which were encapsulated and annealed at 650 to 800°C for 5 to 80 h. The phase formation at the interface was analyzed in cross sections of these couples using optical and scanning electron microscopy together with energy- and wavelength dispersive X-ray microanalysis. In addition, bulk powder mixtures of Y123 with Pt, Ag or Au were annealed at 800°C for 100 h and phase analysis was performed using X-ray diffraction. At the Pt/Y123 interface a reaction zone grows slowly but decisively at 800°C. Its microstructure is multiphase with YCu-oxides and a fine-grained dispersion of Y 2BaCuO 5 (Y211) with BaCu-oxides. Additional BaPt oxides and other phases are seen in powder mixtures annealed for longer times. Barium is suspected to diffuse out from the superconductor along grain boundaries from as deep as 1 mm, causing the decomposition of Y123 into YCu-oxides in the depleted regions. Ag and Au form a stable contact at the interface to Y123 with no reaction zone or new phases. Interdiffusion at the Ag/Y123 interface at 800°C was too low to be clearly detected. In contrast, Au diffuses very fast into Y123 and at 800°C the solubility is 4.2 mass% Au. Yttrium and barium diffuse much slower into the (Au) phase, Cu diffusion was not detected. Weak traces of decomposition products, mostly Y211 and BaCu-oxides, were observed in bulk powder mixtures of Y123 with Ag or Au annealed at 800°C for 100 h in closed capsules. These decomposition products are considered to be due to the high oxygen pressure in the closed capsule, exceeding the stability limit of Y123, and not due to the reduction of Y123. Both Ag and Au are virtually non-reactive with Y123.

  13. Follow-up of K2 planet candiates with the LCOGT network

    Science.gov (United States)

    Dragomir, Diana; Bayliss, Daniel; Colón, Knicole; Cochran, William; Zhou, George; Brown, Timothy; Shporer, Avi; Espinoza, Nestor; Fulton, Benjamin

    2015-12-01

    K2 has proven to be an outstanding successor to the Kepler mission. It has already revealed dozens of new planet candidates, and unlike those found by the primary mission, many of these systems’ host stars are sufficiently bright to allow extensive follow-up observations. This is especially important since each of the K2 observing campaigns are only ~80 days long, leaving the community with the discovery of exciting new systems but often not enough time coverage to enable a thorough characterization of these systems.We are leading a large effort to observe K2 transiting planet candidates with the LCOGT telescope network. LCOGT’s longitudinal coverage, multiple identical telescopes per site and automated queue observing make it an ideal facility for fast, high-precision and multi-color follow-up. Our program focuses on specific aspects of K2 follow-up for which the network is especially powerful: period determination for candidates with fewer than three K2 transits; transit timing variation monitoring to measure planetary masses, orbital parameters and to search for additional planets in multiple systems; and multi-color photometry to vet planet candidates and carry-out preliminary atmospheric spectroscopy.We will present new results for a selection of systems observed so far through this program. These include K2-19, a multi-planet system extremely close to 3:2 resonance and experiencing transit timing variations with amplitudes as large as one hour; EPIC201702477, a long-period planet with only two K2 transits; WASP-47, a system hosting a hot Jupiter and two K2-discovered small planets; and EPIC201637175b, a disintegrating rocky planet.Our program demonstrates that LCOGT is uniquely positioned to be the primary ground-based photometric follow-up resource for K2 exoplanet discoveries, but also for the numerous bright systems that will result from the TESS mission. LCOGT photometry complements ongoing radial velocity and atmospheric spectroscopy efforts to

  14. Vitamins K1 and K2: The Emerging Group of Vitamins Required for Human Health

    Directory of Open Access Journals (Sweden)

    Gerry Kurt Schwalfenberg

    2017-01-01

    Full Text Available Objective. To review the evidence for the use of vitamin K supplementation in clinical conditions such as osteoporosis, vascular calcification, arthritis, cancer, renal calculi, diabetes, and warfarin therapy. Quality of Evidence. PubMed was searched for articles on vitamin K (K1 and K2 along with books and conference proceedings and health conditions listed above. Level I and II evidence supports the use of vitamins K1 and K2 in osteoporosis and Level II evidence supports vitamin K2 in prevention of coronary calcification and cardiovascular disease. Evidence is insufficient for use in diabetes, arthritis, renal calculi, and cancer. Main Message. Vitamin K2 may be a useful adjunct for the treatment of osteoporosis, along with vitamin D and calcium, rivaling bisphosphonate therapy without toxicity. It may also significantly reduce morbidity and mortality in cardiovascular health by reducing vascular calcification. Vitamin K2 appears promising in the areas of diabetes, cancer, and osteoarthritis. Vitamin K use in warfarin therapy is safe and may improve INR control, although a dosage adjustment is required. Conclusion. Vitamin K supplementation may be useful for a number of chronic conditions that are afflicting North Americans as the population ages. Supplementation may be required for bone and cardiovascular health.

  15. Assembly Stoichiometry of the GluK2/GluK5 Kainate Receptor Complex

    Directory of Open Access Journals (Sweden)

    Andreas Reiner

    2012-03-01

    Full Text Available Ionotropic glutamate receptors assemble as homo- or heterotetramers. One well-studied heteromeric complex is formed by the kainate receptor subunits GluK2 and GluK5. Retention motifs prevent trafficking of GluK5 homomers to the plasma membrane, but coassembly with GluK2 yields functional heteromeric receptors. Additional control over GluK2/GluK5 assembly seems to be exerted by the amino-terminal domains, which preferentially assemble into heterodimers as isolated domains. However, the stoichiometry of the full-length GluK2/GluK5 receptor complex has yet to be determined, as is the case for all non-NMDA glutamate receptors. Here, we address this question, using a single-molecule imaging technique that enables direct counting of the number of each GluK subunit type in homomeric and heteromeric receptors in the plasma membranes of live cells. We show that GluK2 and GluK5 assemble with 2:2 stoichiometry. This is an important step toward understanding the assembly mechanism, architecture, and functional consequences of heteromer formation in ionotropic glutamate receptors.

  16. Dissociative Electron Attachment to the Nitroamine HMX (Octahydro-1,3,5,7-Tetranitro-1,3,5,7-Tetrazocine)

    CERN Document Server

    Postler, J; Matias, C; Mauracher, A; da Silva, F Ferreira; Scheier, P; Limão-Vieira, P; Denifl, S

    2016-01-01

    In the present study, dissociative electron attachment (DEA) measurements with gas phase HMX, octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine, $C_4H_8N_8O_8$, have been performed by means of a crossed electron-molecular beam experiment. The most intense signals are observed at 46 and 176u and assigned to $NO_{2}^{-}$ and $C_3H_6N_5O_{4}^{-}$, respectively. Anion efficiency curves for 15 negatively charged fragments have been measured in the electron energy region from about 0-20 eV with an energy resolution of ~0.7 eV. Product anions are observed mainly in the low energy region, near 0 eV, arising from surprisingly complex reactions associated with multiple bond cleavages and structural and electronic rearrangement. The remarkable instability of HMX towards electron attachment with virtually zero kinetic energy reflects the highly explosive nature of this compound. Substantially different intensity ratios of resonances for common fragment anions allow distinguishing the nitroamines HMX and royal demolition e...

  17. Preparation and Properties of 1, 3, 5, 7-Tetranitro-1, 3, 5, 7-Tetrazocane-based Nanocomposites

    Directory of Open Access Journals (Sweden)

    Xiaofeng Shi

    2015-04-01

    Full Text Available A new insensitive explosive based on octahydro-1, 3, 5, 7-tetranitro-1, 3, 5, 7-tetrazocine (HMX was prepared by spray drying using Viton A as a binder. The HMX sample without binder (HMX-1 was obtained by the same spray drying process also. The samples were characterised by Scanning Electron Microscope, and X-ray diffraction. The Differential Scanning Calorimetry and the impact sensitivity of HMX-1 and nanocomposites were also being tested. The nanocomposite morphology was found to be microspherical (1 μm to 7 μm diameter and composed of many tiny particles, 100 nm to 200 nm in size. The crystal type of HMX-1 and HMX/Viton A agrees with raw HMX. The activation energy of raw HMX, HMX-1 and HMX/Viton A is 523.16 kJ mol-1, 435.74 kJ mol-1 and 482.72 kJ mol-1, respectively. The self-ignition temperatures of raw HMX, HMX-1 and HMX/Viton A is 279.01 °C, 277.63 °C, and 279.34 °C, respectively. The impact sensitivity order of samples is HMX/Viton A < HMX-1 < raw HMX from low to high.Defence Science Journal, Vol. 65, No. 2, March 2015, pp.131-134, DOI:http://dx.doi.org/10.14429/dsj.65.7843

  18. Microaerophilic degradation of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) by three Rhodococcus strains.

    Science.gov (United States)

    Fuller, M E; Perreault, N; Hawari, J

    2010-09-01

    The goal of this study was to compare the degradation of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) by three Rhodococcus strains under anaerobic, microaerophilic (RDX as the sole nitrogen source. RDX and RDX metabolite concentrations were measured over time. Under microaerophilic conditions, the bacteria degraded RDX, albeit about 60-fold slower than under fully aerobic conditions. Only the breakdown product, 4-nitro-2,4-diazabutanal (NDAB) accumulated to measurable concentrations under microaerophilic conditions. RDX degraded quickly under both aerated and static aerobic conditions (DO allowed to drop below 1 mg l(-1)) with the accumulation of both NDAB and methylenedinitramine (MEDINA). No RDX degradation was observed under strict anaerobic conditions. The Rhodococcus strains did not degrade RDX under strict anaerobic conditions, while slow degradation was observed under microaerophilic conditions. The RDX metabolite NDAB was detected under both microaerophilic and aerobic conditions, while MEDINA was detected only under aerobic conditions. IMPACT AND SIGNIFICANCE OF THE STUDY: This work confirmed the production of MEDINA under aerobic conditions, which has not been previously associated with aerobic RDX degradation by these organisms. More importantly, it demonstrated that aerobic rhodococci are able to degrade RDX under a broader range of oxygen concentrations than previously reported.

  19. Toxicity of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) in three vertebrate species.

    Science.gov (United States)

    Johnson, Mark S; McFarland, Craig A; Bazar, Matthew A; Quinn, Michael J; LaFiandra, Emily May; Talent, Larry G

    2010-04-01

    The explosive, octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine or high-melting explosive (HMX), has been found in soils in areas used for testing and training by the military. Many of these areas contain habitat for valued wildlife species. In an effort to better understand the environmental consequences from exposure, a reptilian (western fence lizard [Sceloporus occidentalis]), an amphibian (red-backed salamander [Plethodon cinereus]), and a mammalian species (rabbit [Oryctolagus cuniculus]) were exposed to HMX under controlled laboratory conditions. Lizards and rabbits were exposed to HMX by way of corn oil through gavage, and salamanders were exposed to HMX in soil. Two deaths occurred from acute oral exposures to lizards to 5000 mg HMX/kg BW. Histological and gross pathologic assessment suggested gut impaction as a possible cause of death. Salamanders exposed to concentrations of HMX in soil 24 h after oral exposures. An LD(50) for rabbits was calculated as 93 mg/kg (95% confidence interval 76-117). A subacute 14-day testing regime found a lowest observed effect level of 10 mg/kg-d and a no observed adverse effect level of 5 mg/kg-d based on hyperkinesia and seizure incidence, although changes suggesting functional hepatic alterations were also found. These data suggest that physiologic differences between species, particularly in gastrointestinal structure and function, can affect the absorption of HMX and hence lead to marked differences in toxicity from exposure to the same compound.

  20. The K2-ESPRINT Project I: Discovery of the Disintegrating Rocky Planet K2-22b with a Cometary Head and Leading Tail

    Science.gov (United States)

    Sanchis-Ojeda, R.; Rappaport, S.; Pallè, E.; Delrez, L.; DeVore, J.; Gandolfi, D.; Fukui, A.; Ribas, I.; Stassun, K. G.; Albrecht, S.; Dai, F.; Gaidos, E.; Gillon, M.; Hirano, T.; Holman, M.; Howard, A. W.; Isaacson, H.; Jehin, E.; Kuzuhara, M.; Mann, A. W.; Marcy, G. W.; Miles-Páez, P. A.; Montañés-Rodríguez, P.; Murgas, F.; Narita, N.; Nowak, G.; Onitsuka, M.; Paegert, M.; Van Eylen, V.; Winn, J. N.; Yu, L.

    2015-10-01

    We present the discovery of a transiting exoplanet candidate in the K2 Field-1 with an orbital period of 9.1457 hr: K2-22b. The highly variable transit depths, ranging from ∼0% to 1.3%, are suggestive of a planet that is disintegrating via the emission of dusty effluents. We characterize the host star as an M-dwarf with Teff ≃ 3800 K. We have obtained ground-based transit measurements with several 1-m class telescopes and with the GTC. These observations (1) improve the transit ephemeris; (2) confirm the variable nature of the transit depths; (3) indicate variations in the transit shapes; and (4) demonstrate clearly that at least on one occasion the transit depths were significantly wavelength dependent. The latter three effects tend to indicate extinction of starlight by dust rather than by any combination of solid bodies. The K2 observations yield a folded light curve with lower time resolution but with substantially better statistical precision compared with the ground-based observations. We detect a significant “bump” just after the transit egress, and a less significant bump just prior to transit ingress. We interpret these bumps in the context of a planet that is not only likely streaming a dust tail behind it, but also has a more prominent leading dust trail that precedes it. This effect is modeled in terms of dust grains that can escape to beyond the planet's Hill sphere and effectively undergo “Roche lobe overflow,” even though the planet's surface is likely underfilling its Roche lobe by a factor of 2.

  1. THE K2-ESPRINT PROJECT. I. DISCOVERY OF THE DISINTEGRATING ROCKY PLANET K2-22b WITH A COMETARY HEAD AND LEADING TAIL

    Energy Technology Data Exchange (ETDEWEB)

    Sanchis-Ojeda, R. [Department of Astronomy, University of California, Berkeley, CA 94720 (United States); Rappaport, S.; Dai, F. [Department of Physics, and Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Pallè, E. [Instituto de Astrofísica de Canarias (IAC), E-38205 La Laguna, Tenerife (Spain); Delrez, L. [Institut d’Astrophysique et Géophysique, Université de Liège, allée du 6 Août 17, B-4000 Liège (Belgium); DeVore, J. [Visidyne, Inc., 111 South Bedford St., Suite 103, Burlington, MA 01803 (United States); Gandolfi, D. [Dipartimento di Fisica, Universitá di Torino, via P. Giuria 1, I-10125, Torino (Italy); Fukui, A. [Okayama Astrophysical Observatory, National Astronomical Observatory of Japan, Asakuchi, Okayama 719-0232 (Japan); Ribas, I. [Institut de Ciències de l’Espai (CSIC-IEEC), Campus UAB, Facultat de Ciències, Torre C5, parell, 2a pl., E-08193 Bellaterra (Spain); Stassun, K. G. [Vanderbilt University, Nashville, TN 37235 (United States); Albrecht, S. [Stellar Astrophysics Centre, Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, DK-8000 Aarhus C (Denmark); Gaidos, E. [Department of Geology and Geophysics, University of Hawaii, 1680 East-West Road, Honolulu, HI 96822 (United States); Gillon, M. [Departamento de Astrofísica, Universidad de La Laguna (ULL), E-38206 La Laguna, Tenerife (Spain); Hirano, T. [Department of Earth and Planetary Sciences, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8551 (Japan); and others

    2015-10-20

    We present the discovery of a transiting exoplanet candidate in the K2 Field-1 with an orbital period of 9.1457 hr: K2-22b. The highly variable transit depths, ranging from ∼0% to 1.3%, are suggestive of a planet that is disintegrating via the emission of dusty effluents. We characterize the host star as an M-dwarf with T{sub eff} ≃ 3800 K. We have obtained ground-based transit measurements with several 1-m class telescopes and with the GTC. These observations (1) improve the transit ephemeris; (2) confirm the variable nature of the transit depths; (3) indicate variations in the transit shapes; and (4) demonstrate clearly that at least on one occasion the transit depths were significantly wavelength dependent. The latter three effects tend to indicate extinction of starlight by dust rather than by any combination of solid bodies. The K2 observations yield a folded light curve with lower time resolution but with substantially better statistical precision compared with the ground-based observations. We detect a significant “bump” just after the transit egress, and a less significant bump just prior to transit ingress. We interpret these bumps in the context of a planet that is not only likely streaming a dust tail behind it, but also has a more prominent leading dust trail that precedes it. This effect is modeled in terms of dust grains that can escape to beyond the planet's Hill sphere and effectively undergo “Roche lobe overflow,” even though the planet's surface is likely underfilling its Roche lobe by a factor of 2.

  2. The ternary system K2SO4MgSO4CaSO4

    Science.gov (United States)

    Rowe, J.J.; Morey, G.W.; Silber, C.C.

    1967-01-01

    Melting and subsolidus relations in the system K2SO4MgSO4CaSO4 were studied using heating-cooling curves, differential thermal analysis, optics, X-ray diffraction at room and high temperatures and by quenching techniques. Previous investigators were unable to study the binary MgSO4CaSO4 system and the adjacent area in the ternary system because of the decomposition of MgSO4 and CaSO4 at high temperatures. This problem was partly overcome by a novel sealed-tube quenching method, by hydrothermal synthesis, and by long-time heating in the solidus. As a result of this study, we found: (1) a new compound, CaSO4??3MgSO4 (m.p. 1201??C) with a field extending into the ternary system; (2) a high temperature form of MgSO4 with a sluggishly reversible inversion. An X-ray diffraction pattern for this polymorphic form is given; (3) the inversion of ??-CaSO4 (anhydrite) to ??-CaSO4 at 1195??C, in agreement with grahmann; (1) (4) the melting point of MgSO4 is 1136??C and that of CaSO4 is 1462??C (using sealed tube methods to prevent decomposition of the sulphates); (5) calcium langbeinite (K2SO4??2CaSO4) is the only compound in the K2SO4CaSO4 binary system. This resolved discrepancies in the results of previous investigators; (6) a continuous solid solution series between congruently melting K2SOP4??2MgSO4 (langbeinite) and incongruently melting K2SO4??2CaSO4 (calcium langbeinite); (7) the liquidus in the ternary system consists of primary phase fields of K2SO4, MgSO4, CaSO4, langbeinite-calcium langbeinite solid solution, and CaSO4??3MgSO4. The CaSO4 field extends over a large portion of the system. Previously reported fields for the compounds (K2SO4??MgSO4??nCaSO4), K2SO4??3CaSO4 and K2SO4??CaSO4 were not found; (8) a minimum in the ternary system at: 740??C, 25% MgSO4, 6% CaSO4, 69% K2SO4; and ternary eutectics at 882??C, 49% MgSO4, 19% CaSO4, 32% K2SO4; and 880??, 67??5% MgSO4, 5% CaSO4, 27??5% K2SO4. ?? 1967.

  3. AC Humidity Sensing Properties of Mesoporous K2CO3-SiO2 Composite Materials

    Directory of Open Access Journals (Sweden)

    Liang Guo

    2016-01-01

    Full Text Available The mesoporous silica SBA-15 and mesoporous K2CO3-SiO2 composite material were synthesized. Characterization of microstructure and morphology of materials indicated that the composite material had saved the porous framework of mesoporous silica SBA-15. Humidity sensing properties of different inverse proportion K2CO3-SiO2 composite material were studied and we found that the sample with 0.16 g/g K2CO3 exhibited excellent linearity in the wide humidity range. The complex impedance changed five orders of magnitude from 11% RH to 95% RH. The rapid response and recovery time were 10 s and 38 s, respectively. Finally a feasible ion transfer mechanism was brought forward to explain the sensing mechanism.

  4. Activation of Anhydrate Phosphogypsmn by K2SO4 and Hemihydrate Gypsum

    Institute of Scientific and Technical Information of China (English)

    YANG Min; QIAN Jueshi

    2011-01-01

    Lime pretreated phosphogypsum(PG) was calcined at 500 ℃ to produce anhydrate gypsum cement.Due to the slow hydration of anhydrate gypsum,additives,K2SO4 and hemihydrate gypsum were selected to accelerate the hydration of anhydrate.The hydration characteristics,the resistance to hydrodynamic water,and the mineralogical studies were investigated.The experimental results suggest that activated by K2SO4 and hemihydrate,anhydrate PG hydrates much more rapidly than that in the presence of only K2SO4 or in the absence of additives.The binder has proper setting time,good strength development,and relatively better resistance to water.The hardened binder has hydrated products of rod or stick like shaped dihydrate gypsum crystals.

  5. K2: Extending Kepler's Power to the Ecliptic-Ecliptic Plane Input Catalog

    Science.gov (United States)

    Huber, Daniel; Bryson, Stephen T.

    2017-01-01

    This document describes the Ecliptic Plane Input Catalog (EPIC) for the K2 mission (Howell et al. 2014). The primary purpose of this catalog is to provide positions and Kepler magnitudes for target management and aperture photometry. The Ecliptic Plane Input Catalog is hosted at MAST (http://archive.stsci.edu/k2/epic/search.php) and should be used for selecting targets when ever possible. The EPIC is updated for future K2 campaigns as their fields of view are finalized and the associated target management is completed. Table 0 summarizes the EPIC updates to date and the ID range for each. The main algorithms used to construct the EPIC are described in Sections 2 through 4. The details for individual campaigns are described in the subsequent sections, with the references listed in the last section. Further details can be found in Huber et al. (2016).

  6. Dietary vitamin K2 supplement improves bone status after lung and heart transplantation.

    Science.gov (United States)

    Forli, Liv; Bollerslev, Jens; Simonsen, Svein; Isaksen, Gunhild A; Kvamsdal, Kari E; Godang, Kristin; Gadeholt, Gaut; Pripp, Are H; Bjortuft, Oystein

    2010-02-27

    Osteoporosis is a problem after transplantation. Studies since the last year indicate that vitamin K plays a role in optimal bone health. The aim of this randomized, double blind, prospective longitudinal study was to investigate the effect of a dietary supplement with vitamin K2 (180 microg menakinon-7) on bone mass, the first year after lung and heart transplantation. After preoperative baseline investigation of bone mass and bone-related biochemistry, 35 lung and 59 heart recipients were postoperatively randomized to vitamin K2 or placebo and reinvestigated the following year. In all recipients, 1 year after solid organ transplantation, the difference between vitamin K2 and placebo for the lumbar spine (L2-L4) bone mineral density (BMD) was 0.028 (SE 0.014) g/cm(2), P=0.055 and for L2 to L4 bone mineral content was 1.33 (SE 1.91) g/cm(2) (P=0.5). In lung recipients separately, the difference for bone mineral content was 3.39 g (SE 1.65), P=0.048 and in heart recipients 0.45 (SE 0.02) g, P=0.9 after controlling for baseline measures. In a forward stepwise linear regression analysis fitted to model differences in the L2 to L4 BMD, controlled for possible confounding variables (including use of bisphosphonate), and the only significant predictors were organ (B=-0.065 g/cm(2), Pvitamin K2 (B=0.034 g/cm(2), P=0.019). Insufficient vitamin D status was common, and the parathyroid hormone was highest in the K2 group indicating a higher need for vitamin D. One year of vitamin K2 supplement suggest a favorable effect on lumbar spine BMD with different response in lung and heart recipients. Vitamin D status should receive more attention.

  7. Neutrino induced pion production at MiniBooNE and K2K

    CERN Document Server

    Leitner, T; Mosel, U; Alvarez-Ruso, L

    2008-01-01

    We investigate charged and neutral current neutrino induced incoherent pion production off nuclei at MiniBooNE and K2K energies within the GiBUU model. We assume impulse approximation and treat the nucleus as a local Fermi gas of nucleons bound in a mean-field potential. In-medium spectral functions are also taken into account. The outcome of the initial neutrino nucleon reaction undergoes complex hadronic final state interactions. We present results for neutral current pi^0 and charged current pi^+ production and compare to MiniBooNE and K2K data.

  8. Phase transitions and electrical properties of the ferroelectric K2Ba4Nb10O30

    Energy Technology Data Exchange (ETDEWEB)

    Cherner, IA.E.; Shpak, L.A.; Gol' tsov, IU.I.; Filip' ev, V.S.

    1987-03-01

    A transition of the second kind between two ferroelectric tetragonal phases was observed at a temperature of 290 K in K2Ba4Nb10O30. This transition is not connected with the appearance or modification of spontaneous polarization, and is accompanied by peaks of permittivity and dielectric losses. The anomaly in the temperature dependence of specific resistance observed previously in polycrystalline K2Ba4Nb10O30 at 220-410 K is connected with the formation and modification of the electrical state of barriers at intercrystalline boundaries. 10 references.

  9. That's How We Roll: The NASA K2 Mission Science Products and Their Performance Metrics

    Science.gov (United States)

    Van Cleve, Jeffrey E.; Howell, Steve B.; Smith, Jeffrey C.; Clarke, Bruce D.; Thompson, Susan E.; Bryson, Stephen T.; Lund, Mikkel N.; Handberg, Rasmus; Chaplin, William J.

    2016-07-01

    NASA's exoplanet Discovery mission Kepler was reconstituted as the K2 mission a year after the failure of the second of Kepler's four reaction wheels in 2013 May. Fine control of the spacecraft pointing is now accomplished through the use of the two remaining well-functioning reaction wheels and balancing the pressure of sunlight on the solar panels, which constrains K2 observations to fields in the ecliptic for up to approximately 80 days each. This pseudo-stable mechanism gives typical roll motion in the focal plane of 1.0 pixels peak-to-peak over 6 hr at the edges of the field, two orders of magnitude greater than typical 6 hr pointing errors in the Kepler primary mission. Despite these roll errors, the joint performance of the flight system and its modified science data processing pipeline restores much of the photometric precision of the primary mission while viewing a wide variety of targets, thus turning adversity into diversity. We define K2 performance metrics for data compression and pixel budget available in each campaign; the photometric noise on exoplanet transit and stellar activity timescales; residual correlations in corrected long-cadence light curves; and the protection of test sinusoidal signals from overfitting in the systematic error removal process. We find that data compression and noise both increase linearly with radial distance from the center of the field of view, with the data compression proportional to star count as well. At the center, where roll motion is nearly negligible, the limiting 6 hr photometric precision for a quiet 12th magnitude star can be as low as 30 ppm, only 25% higher than that of Kepler. This noise performance is achieved without sacrificing signal fidelity; test sinusoids injected into the data are attenuated by less than 10% for signals with periods upto 15 days, so that a wide range of stellar rotation and variability signatures are preserved by the K2 pipeline. At timescales relevant to asteroseismology, light

  10. Electron attachment to hydrated oligonucleotide dimers: guanylyl-3',5'-cytidine and cytidylyl-3',5'-guanosine.

    Science.gov (United States)

    Gu, Jiande; Xie, Yaoming; Schaefer, Henry F

    2010-05-03

    The dinucleoside phosphate deoxycytidylyl-3',5'-deoxyguanosine (dCpdG) and deoxyguanylyl-3',5'-deoxycytidine (dGpdC) systems are among the largest to be studied by reliable theoretical methods. Exploring electron attachment to these subunits of DNA single strands provides significant progress toward definitive predictions of the electron affinities of DNA single strands. The adiabatic electron affinities of the oligonucleotides are found to be sequence dependent. Deoxycytidine (dC) on the 5' end, dCpdG, has larger adiabatic electron affinity (AEA, 0.90 eV) than dC on the 3' end of the oligomer (dGpdC, 0.66 eV). The geometric features, molecular orbital analyses, and charge distribution studies for the radical anions of the cytidine-containing oligonucleotides demonstrate that the excess electron in these anionic systems is dominantly located on the cytosine nucleobase moiety. The pi-stacking interaction between nucleobases G and C seems unlikely to improve the electron-capturing ability of the oligonucleotide dimers. The influence of the neighboring base on the electron-capturing ability of cytosine should be attributed to the intensified proton accepting-donating interaction between the bases. The present investigation demonstrates that the vertical detachment energies (VDEs) of the radical anions of the oligonucleotides dGpdC and dCpdG are significantly larger than those of the corresponding nucleotides. Consequently, reactions with low activation barriers, such as those for O-C sigma bond and N-glycosidic bond breakage, might be expected for the radical anions of the guanosine-cytosine mixed oligonucleotides.

  11. Elevated root retention of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in coniferous trees.

    Science.gov (United States)

    Schoenmuth, Bernd; Mueller, Jakob O; Scharnhorst, Tanja; Schenke, Detlef; Büttner, Carmen; Pestemer, Wilfried

    2014-03-01

    For decades, the explosive RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) has been used for military and industrial applications. Residues of RDX pollute soils in large areas globally and the persistence and high soil mobility of these residues can lead to leaching into groundwater. Dendroremediation, i.e. the long-term use of trees to clean up polluted soils, is gaining acceptance as a green and sustainable strategy. Although the coniferous tree species Norway spruce and Scots pine cover large areas of military land in Central Europe, the potential of any coniferous tree for dendroremediation of RDX is still unknown. In this study, uptake experiments with a (14)C-labelled RDX solution (30 mg L(-1)) revealed that RDX was predominantly retained in the roots of 6-year-old coniferous trees. Only 23 % (pine) to 34 % (spruce) of RDX equivalents (RDXeq) taken up by the roots were translocated to aboveground tree compartments. This finding contrasts with the high aerial accumulation of RDXeq (up to 95 %) in the mass balances of all other plant species. Belowground retention of RDXeq is relatively stable in fine root fractions, since water leaching from tissue homogenates was less than 5 %. However, remobilisation from milled coarse roots and tree stubs reached up to 53 %. Leaching from homogenised aerial tree material was found to reach 64 % for needles, 58 % for stems and twigs and 40 % for spring sprouts. Leaching of RDX by precipitation increases the risk for undesired re-entry into the soil. However, it also opens the opportunity for microbial mineralisation in the litter layer or in the rhizosphere of coniferous forests and offers a chance for repeated uptake of RDX by the tree roots.

  12. K2 variable catalogue - II. Machine learning classification of variable stars and eclipsing binaries in K2 fields 0-4

    Science.gov (United States)

    Armstrong, D. J.; Kirk, J.; Lam, K. W. F.; McCormac, J.; Osborn, H. P.; Spake, J.; Walker, S.; Brown, D. J. A.; Kristiansen, M. H.; Pollacco, D.; West, R.; Wheatley, P. J.

    2016-02-01

    We are entering an era of unprecedented quantities of data from current and planned survey telescopes. To maximize the potential of such surveys, automated data analysis techniques are required. Here we implement a new methodology for variable star classification, through the combination of Kohonen Self-Organizing Maps (SOMs, an unsupervised machine learning algorithm) and the more common Random Forest (RF) supervised machine learning technique. We apply this method to data from the K2 mission fields 0-4, finding 154 ab-type RR Lyraes (10 newly discovered), 377 δ Scuti pulsators, 133 γ Doradus pulsators, 183 detached eclipsing binaries, 290 semidetached or contact eclipsing binaries and 9399 other periodic (mostly spot-modulated) sources, once class significance cuts are taken into account. We present light-curve features for all K2 stellar targets, including their three strongest detected frequencies, which can be used to study stellar rotation periods where the observed variability arises from spot modulation. The resulting catalogue of variable stars, classes, and associated data features are made available online. We publish our SOM code in PYTHON as part of the open source PYMVPA package, which in combination with already available RF modules can be easily used to recreate the method.

  13. Rock Visualization System. Technical description (RVS v.3.5)

    Energy Technology Data Exchange (ETDEWEB)

    Curtis, P.; Elfstroem, M.; Markstroem, I. [FB Engineering, Goeteborg (Sweden)

    2004-03-01

    The Rock Visualization System (RVS) has been developed by SKB for use in visualizing geological and engineering data in 3D. The purpose of this report is to provide a technical description of RVS aimed at potential program users and interested parties as well as fulfilling the function of a more general RVS reference that can be cited when writing other technical reports. It is a description of RVS version 3.5. Updated versions of this report or addenda will be made available following further development of RVS and the release of subsequent versions of the program. The report covers the following main items: Technical description of the program with illustrations and examples; Limitations of the program and of functionality. For most RVS functions step-by-step tutorials are available describing how a particular function can be used to carryout a specific task. A complete set of updated tutorials is issued with each new version release of the RVS program. However, the tutorials do not cover all the possible uses of all the individual functions but rather give an overall view of their functionality. A detailed description of every RVS function and how it can be used is included in the RVS online Help system.

  14. Evolution of geochemical conditions in SFL 3-5

    Energy Technology Data Exchange (ETDEWEB)

    Karlsson, Fred [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Lindgren, M.; Skagius, K.; Wiborgh, M. [Kemakta Konsult AB, Stockholm (Sweden); Engkvist, I. [Barsebaeck Kraft AB (Sweden)

    1999-12-01

    The evolution of geochemical conditions in the repository for long-lived low- and intermediate-level waste, SFL 3-5, and in the vicinity of the repository are important when predicting the retention of radionuclides and the long-term stability of engineered barriers. In this study the initial conditions at different repository sites at 300 - 400 m depth, the influence of repository construction and operation, the expected conditions after repository closure and saturation, and the evolution in a long-term perspective are discussed. Groundwaters that are found at these depths have near-neutral pH and are reducing in character, but the composition can vary from saline to non-saline water. The water chemistry in the near-field will mainly be influenced by the composition of the groundwater and by the large amounts of cementitious material that can be found in the repository. Disturbances caused during construction and operation are not expected to be permanent. Studies of old concrete indicate that leaching of concrete is a slow process. The geochemical conditions in the repository are therefore expected to be stable and prevail for hundreds of thousand years. However, the evolution of the surrounding environment may influence the conditions in long-term perspective.

  15. 3.5 TeV: Patience pays dividends

    CERN Multimedia

    Rolf Heuer

    2010-01-01

    In my message this week, I’d like to congratulate the LHC team on accelerating two beams to 3.5 TeV in the early hours of this morning. The timing could not have been better. Coming during a week of CERN Council meetings, it allowed us to show delegates the great progress we’re making. The occasion also gave us the opportunity to set out again the prudent step-by-step approach that we’re taking to get the LHC up and running, and it was refreshing to hear one member of the Scientific Policy Committee declare on Monday that we should never forget that the LHC is not a turnkey machine.With the progress the LHC is making, that simple fact would be easy to overlook. The figures coming back from this first run are already quite remarkable. In Week 10, the LHC’s availability for the operators was over 65%: it usually takes a new accelerator years to reach that level. And over the last few weeks, operation of the LHC at 450 GeV has become routinely reproducible, which i...

  16. Dielectric Properties and Thermal Decomposition of K2Ni(SO4)2 Crystals

    Science.gov (United States)

    Marzougui, H.; Sánchez, V.; León-Luis, S. F.; Lozano-Gorrín, A. D.; Lalla, E.; Torres, M. E.; Attia-Essaies, S.; Ben Hassen-Chehimi, D.

    2016-11-01

    The dielectric properties of K2Ni(SO4)2 crystals have been measured as a function of frequency (100 Hz to 1 MHz) and temperature (400 K to 900 K). The results show that the real part of the conductivity follows the universal dielectric response, where the activation energy varies from 0.72 eV up to 1.08 eV for the temperature range studied. On the other hand, the permittivity and conductivity parameters present a change in their frequency dependence at around 620 K, suggesting that a phase transition might be taking place. To understand this unexpected result, complementary study by thermogravimetric and differential thermal analyses, X-ray powder diffraction analysis, and Raman spectroscopy measurements was carried out. The results suggest thermal decomposition of the original compound at 620 K as follows: 2K2Ni(SO4)2 → K2Ni2(SO4)3 + K2SO4.

  17. K2_SPH Method and its Application for 2-D Water Wave Simulation

    Institute of Scientific and Technical Information of China (English)

    Zhenhong Hu; Xing Zheng; Wenyang Duan; Qingwei Ma

    2011-01-01

    Smoothed Particle Hydrodynamics(SPH)is a Lagrangian meshless particle method.However,its low accuracy of kernel approximation when particles are distributed disorderly or located near the boundary is an obstacle standing in the way of its wide application.Adopting the Taylor series expansion method and solving the integral equation matrix,the second order kernel approximation method can be obtained,namely K2_SPH,which is discussed in this paper.This method is similar to the Finite Particle Method.With the improvement of kernel approximation,some numerical techniques should be adopted for different types of boundaries,such as a free surface boundary and solid boundary,which are two key numerical techniques of K2_SPH for water wave simulation.This paper gives some numerical results of two dimensional water wave simulations involving standing wave and sloshing tank problems by using K2_SPH.From the comparison of simulation results,the K2 SPH method is more reliable than standard SPH.

  18. Photo-dynamical mass determination of the multi-planetary system K2-19

    CERN Document Server

    Barros, S C C; Demangeon, O; Tsantaki, M; Santerne, A; Armstrong, D J; Barrado, D; Brown, D; Deleuil, M; Lillo-Box, J; Osborn, H; Pollacco, D; Abe, L; Andre, P; Bendjoya, P; Boisse, I; Bonomo, A S; Bouchy, F; Bruno, G; Cerda, J Rey; Courcol, B; Díaz, R F; Hébrard, G; Kirk, J; Lachurié, J C; Lam, K W F; Martinez, P; McCormac, J; Moutou, C; Rajpurohit, A; Rivet, J -P; Spake, J; Suarez, O; Toublanc, D; Walker, S R

    2015-01-01

    K2-19 is the second multi-planetary system discovered with K2 observations. The system is composed of two Neptune size planets close to the 3:2 mean-motion resonance. To better characterise the system we obtained two additional transit observations of K2-19b and five additional radial velocity observations. These were combined with K2 data and fitted simultaneously with the system dynamics (photo-dynamical model) which increases the precision of the transit time measurements. The higher transit time precision allows us to detect the chopping signal of the dynamic interaction of the planets that in turn permits to uniquely characterise the system. Although the reflex motion of the star was not detected, dynamic modelling of the system allowed us to derive planetary masses of $M_b= 44 \\pm 12\\, M_{\\oplus}$ and $M_c = 15.9 \\pm 7.0\\, M_{\\oplus}$ for the inner and the outer planets respectively, leading to densities close to Uranus. We also show that our method allows the derivation of mass ratios using only the 80...

  19. New planetary and eclipsing binary candidates from campaigns 1-6 of the K2 mission

    Science.gov (United States)

    Barros, S. C. C.; Demangeon, O.; Deleuil, M.

    2016-10-01

    Context. With only two functional reaction wheels, Kepler cannot maintain stable pointing at its original target field and has entered a new mode of observation called K2. Aims: We describe a new pipeline to reduce K2 pixel files into light curves that are later searched for transit like features. Methods: Our method is based on many years of experience in planet hunting for the CoRoT mission. Owing to the unstable pointing, K2 light curves present systematics that are correlated with the target position in the charge coupled device (CCD). Therefore, our pipeline also includes a decorrelation of this systematic noise. Our pipeline is optimised for bright stars for which spectroscopic follow-up is possible. We achieve a maximum precision on 6 hours of 6 ppm. The decorrelated light curves are searched for transits with an adapted version of the CoRoT alarm pipeline. Results: We present 172 planetary candidates and 327 eclipsing binary candidates from campaigns 1, 2, 3, 4, 5, and 6 of K2. Both the planetary candidates and eclipsing binary candidates lists are made public to promote follow-up studies. The light curves will also be available to the community. Full Tables A.1 and A.2 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/594/A100

  20. Parental Engagement Using Effective Communication for K-2 Students in an Urban School

    Science.gov (United States)

    Bradley, Lynn Renee'

    2013-01-01

    Parental involvement is a factor in student achievement. Low parental engagement at home and school has created a problem in an urban elementary school. Guided by Epstein's 6 types of parental involvement, the purpose of this case study was to examine and describe the perspectives of 17 parents of K-2 students in an urban school in Michigan. Few…

  1. EPIC 201585823, a rare triple-mode RR Lyrae star discovered in K2 mission data

    DEFF Research Database (Denmark)

    Kurtz, Donald W.; Bowman, Dominic M.; Ebo, Simon J.

    2016-01-01

    We have discovered a new, rare triple-mode RR Lyr star, EPIC 201585823, in the Kepler K2 mission Campaign 1 data. This star pulsates primarily in the fundamental and first-overtone radial modes, and, in addition, a third non-radial mode. The ratio of the period of the non-radial mode to that of t...

  2. Crawling and/or Squatting: A Saleable Work Skill. Occupation Simulation Packet. Grades K-2nd.

    Science.gov (United States)

    Montgomery, Margery

    This teacher's guide for grades K-2 contains simulated work experiences for students using the isolated skill concept, crawling and/or squatting. Teacher instructions include objectives, evaluation, and sequence of activities. The guide contains pre-tests and post-tests with instructions and answer keys. Three pre-skill activities are suggested,…

  3. Photometry of Very Bright Stars with Kepler and K2 Smear Data

    CERN Document Server

    Pope, Benjamin; Huber, Daniel; Murphy, Simon; Bedding, Tim; Caldwell, Douglas; Sarai, Aleksa; Aigrain, Suzanne; Barclay, Thomas

    2015-01-01

    High-precision time series photometry with the Kepler satellite has been crucial to our understanding both of exoplanets, and via asteroseismology, of stellar physics. After the failure of two reaction wheels, the Kepler satellite has been repurposed as Kepler-2 (K2), observing fields close to the ecliptic plane. As these fields contain many more bright stars than the original Kepler field, K2 provides an unprecedented opportunity to study nearby objects amenable to detailed follow-up with ground-based instruments. Due to bandwidth constraints, only a small fraction of pixels can be downloaded, with the result that most bright stars which saturate the detector are not observed. We show that engineering data acquired for photometric calibration, consisting of collateral `smear' measurements, can be used to reconstruct light curves for bright targets not otherwise observable with Kepler/K2. Here we present some examples from Kepler Quarter 6 and K2 Campaign 3, including the delta Scuti variables HD 178875 and 7...

  4. Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health.

    Science.gov (United States)

    Maresz, Katarzyna

    2015-02-01

    Inadequate calcium intake can lead to decreased bone mineral density, which can increase the risk of bone fractures. Supplemental calcium promotes bone mineral density and strength and can prevent osteoporosis. Recent scientific evidence, however, suggests that elevated consumption of calcium supplements may raise the risk for heart disease and can be connected with accelerated deposit of calcium in blood-vessel walls and soft tissues. In contrast, vitamin K2 is associated with the inhibition of arterial calcification and arterial stiffening. An adequate intake of vitamin K2 has been shown to lower the risk of vascular damage because it activates matrix GLA protein (MGP), which inhibits the deposits of calcium on the walls. Vitamin K, particularly as vitamin K2, is nearly nonexistent in junk food, with little being consumed even in a healthy Western diet. Vitamin K deficiency results in inadequate activation of MGP, which greatly impairs the process of calcium removal and increases the risk of calcification of the blood vessels. An increased intake of vitamin K2 could be a means of lowering calcium-associated health risks.

  5. Discovery Bottles: A Unique Inexpensive Tool for the K-2 Science Classroom

    Science.gov (United States)

    Watson, Sandy

    2008-01-01

    Discover discovery bottles! These wide-mouth plastic containers of any size filled with objects of different kinds can be terrific tools for science explorations and a great way to cultivate science minds in a K-2 science classroom. In addition, the author has found them to be a useful, inexpensive, and engaging way to help students develop skills…

  6. A conjecture on a class of elements of finite order in K2Fp

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    For a local field F the finite subgroups of K2F are expressed by a class of special elements of finite order, which makes a famous theorem built by Moore, Carroll, Tate and Merkurjev more explicit and also disproves a conjecture posed by Browkin.

  7. Teaching Nature of Science to K-2 Students: What understandings can they attain?

    Science.gov (United States)

    Akerson, Valarie; Donnelly, Lisa A.

    2010-01-01

    This study explored the influence of a Saturday Science program that used explicit reflective instruction through contextualized and decontextualized guided and authentic inquiry on K-2 students' views of nature of science (NOS). The six-week program ran for 2.5 hours weekly and emphasized NOS in a variety of science content areas, culminating in an authentic inquiry designed and carried out by the K-2 students. The Views of Nature of Science Form D was used to interview K-2 students pre- and post-instruction. Copies of student work were retained for content analysis. Videotapes made of each week's science instruction were reviewed to ensure that explicit reflective NOS instruction took place. Explicit NOS teaching strategies included (1) introducing NOS through decontextualized activities, (2) embedding NOS into science content through contextualized activities, (3) using children's literature, (4) debriefings and embedded NOS assessments, and (5) guided and student-designed inquiries. Results indicate that K-2 students improved their NOS views over the course of the program, suggesting that they are developmentally ready for these concepts. Students developed adequate views of the distinction between observation and inference, the creative NOS, the tentative NOS, the empirical NOS, and to a lesser degree, the subjective NOS.

  8. MAIN-BELT ASTEROIDS IN THE K2 ENGINEERING FIELD OF VIEW

    Energy Technology Data Exchange (ETDEWEB)

    Szabó, R.; Sárneczky, K.; Szabó, Gy. M.; Pál, A.; Kiss, Cs. P.; Kiss, L. L. [Konkoly Observatory, Research Centre for Astronomy and Earth Sciences, Hungarian Academy of Sciences, H-1121 Budapest, Konkoly Thege Miklós út 15-17 (Hungary); Csák, B. [Gothard-Lendület Research Team, H-9704 Szombathely, Szent Imre herceg út 112 (Hungary); Illés, L.; Rácz, G., E-mail: rszabo@konkoly.hu [Eötvös Loránd Tudományegyetem, H-1117 Pázmány Péter sétány 1/A, Budapest (Hungary)

    2015-03-15

    Unlike NASA’s original Kepler Discovery Mission, the renewed K2 Mission will target the plane of the Ecliptic, observing each field for approximately 75 days. This will bring new opportunities and challenges, in particular the presence of a large number of main-belt asteroids that will contaminate the photometry. The large pixel size makes K2 data susceptible to the effects of apparent minor planet encounters. Here, we investigate the effects of asteroid encounters on photometric precision using a subsample of the K2 engineering data taken in 2014 February. We show examples of asteroid contamination to facilitate their recognition and distinguish these events from other error sources. We conclude that main-belt asteroids will have considerable effects on K2 photometry of a large number of photometric targets during the Mission that will have to be taken into account. These results will be readily applicable for future space photometric missions applying large-format CCDs, such as TESS and PLATO.

  9. Uninterrupted optical light curves of main-belt asteroids from the K2 Mission

    CERN Document Server

    Szabó, R; Sárneczky, K; Szabó, Gy M; Molnár, L; Kiss, L L; Hanyecz, O; Plachy, E; Kiss, Cs

    2016-01-01

    Due to the failure of the second reaction wheel, a new mission was conceived for the otherwise healthy Kepler space telescope. In the course of the K2 Mission, the telescope is staring at the plane of the Ecliptic, hence thousands of Solar System bodies cross the K2 fields, usually causing extra noise in the highly accurate photometric data. In this paper we follow the someone's noise is another one's signal principle and investigate the possibility of deriving continuous asteroid light curves, that has been unprecedented to date. In general, we are interested in the photometric precision that the K2 Mission can deliver on moving Solar System bodies. In particular, we investigate space photometric optical light curves of main-belt asteroids. We study the K2 superstamps covering the M35 and Neptune/Nereid fields observed in the long cadence (29.4-min sampling) mode. Asteroid light curves are generated by applying elongated apertures. We use the Lomb-Scargle method to find periodicities due to rotation. We deri...

  10. Two-photon excitation spectra of Cr3 :K2NaScF6

    Science.gov (United States)

    Bartram, R. H.; Wein, G. R.; Hamilton, D. S.; Sliwczuk, U.; Rinzler, A. G.

    Two-photon excitation (TPE) spectra of Cr3+:K2NaScF6 exhibit unexpected features including a forbidden transition, extended progressions, a split zero-phonon line and anomalous polarization anisotropy. These features are explained by departures from standard approximations.

  11. Time-series Analysis of Broadband Photometry of Neptune from K2

    DEFF Research Database (Denmark)

    Rowe, Jason F.; Gaulme, Patrick; Lissauer, Jack J.

    2017-01-01

    We report here on our search for excess power in photometry of Neptune collected by the K2 mission that may be due to intrinsic global oscillations of the planet Neptune. To conduct this search, we developed new methods to correct for instrumental effects such as intrapixel variability and gain v...

  12. A Continuum of Accretion Burst Behavior in Young Stars Observed by K2

    Science.gov (United States)

    Cody, Ann Marie; Hillenbrand, Lynne A.; David, Trevor J.; Carpenter, John M.; Everett, Mark E.; Howell, Steve B.

    2017-02-01

    We present 29 likely members of the young ρ Oph or Upper Sco regions of recent star formation that exhibit “accretion burst” type light curves in K2 time series photometry. The bursters were identified by visual examination of their ∼80-day light curves, though all satisfy the Mtheory of pre-main sequence accretion history.

  13. A preliminary study of the RR Lyrae stars observed in K2 Campaign 3

    CERN Document Server

    Juhász, Á; Plachy, E

    2016-01-01

    We have started a comprehensive analysis of the Kepler K2 Field 3 data set. Our goals are to assess the statistics of the sample, and to search for peculiar stars. We found a candidate triple-mode RRab star, where the first and ninth overtones also seem to be excited.

  14. Main-Belt Asteroids in the K2 Engineering Field of View

    CERN Document Server

    Szabó, R; Szabó, Gy M; Pál, A; Kiss, Cs P; Csák, B; Illés, L; Rácz, G; Kiss, L L

    2015-01-01

    Unlike NASA's original Kepler Discovery Mission, the renewed K2 Mission will stare at the plane of the Ecliptic, observing each field for approximately 75 days. This will bring new opportunities and challenges, in particular the presence of a large number of main-belt asteroids that will contaminate the photometry. The large pixel size makes K2 data susceptible to the effect of apparent minor planet encounters. Here we investigate the effects of asteroid encounters on photometric precision using a sub-sample of the K2 Engineering data taken in February, 2014. We show examples of asteroid contamination to facilitate their recognition and distinguish these events from other error sources. We conclude that main-belt asteroids will have considerable effects on K2 photometry of a large number of photometric targets during the Mission, that will have to be taken into account. These results will be readily applicable for future space photometric missions applying large-format CCDs, such as TESS and PLATO.

  15. -dependence of the effective weak hamiltonian and K -> 2 amplitudes in chiral-bag model

    Energy Technology Data Exchange (ETDEWEB)

    Horvat, D.; Narancic, Z.; Ilakovac, A.; Tadic, D.

    1989-03-01

    This paper studies the -dependence of the operator matrix elements. Although the -dependence must in principle cancel as illustrated in the paper by using a simple pedagogical model, in practice the choice of markedly influences the theoretical predictions for K -> 2 decays.

  16. K2: A new method for the detection of galaxy clusters based on CFHTLS multicolor images

    CERN Document Server

    Thanjavur, Karun; Crampton, David

    2009-01-01

    We have developed a new method, K2, optimized for the detection of galaxy clusters in multicolor images. Based on the Red Sequence approach, K2 detects clusters using simultaneous enhancements in both colors and position. The detection significance is robustly determined through extensive Monte-Carlo simulations and through comparison with available cluster catalogs based on two different optical methods, and also on X-ray data. K2 also provides quantitative estimates of the candidate clusters' richness and photometric redshifts. Initially K2 was applied to 161 sq deg of two color gri images of the CFHTLS-Wide data. Our simulations show that the false detection rate, at our selected threshold, is only ~1%, and that the cluster catalogs are ~80% complete up to a redshift of 0.6 for Fornax-like and richer clusters and to z ~0.3 for poorer clusters. Based on Terapix T05 release gri photometric catalogs, 35 clusters/sq deg are detected, with 1-2 Fornax-like or richer clusters every two square degrees. Catalogs co...

  17. Ovine ruminal microbes are capable of biotransforming hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX).

    Science.gov (United States)

    Eaton, H L; De Lorme, M; Chaney, R L; Craig, A M

    2011-08-01

    Bioremediation is of great interest in the detoxification of soil contaminated with residues from explosives such as hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). Although there are numerous forms of in situ and ex situ bioremediation, ruminants would provide the option of an in situ bioreactor that could be transported to the site of contamination. Bovine rumen fluid has been previously shown to transform 2,4,6-trinitrotoluene (TNT), a similar compound, in 4 h. In this study, RDX incubated in whole ovine rumen fluid was nearly eliminated within 4 h. Whole ovine rumen fluid was then inoculated into five different types of media to select for archaeal and bacterial organisms capable of RDX biotransformation. Cultures containing 30 μg mL(-1) RDX were transferred each time the RDX concentration decreased to 5 μg mL(-1) or less. Time point samples were analyzed for RDX biotransformation by HPLC. The two fastest transforming enrichments were in methanogenic and low nitrogen basal media. After 21 days, DNA was extracted from all enrichments able to partially or completely transform RDX in 7 days or less. To understand microbial diversity, 16S rRNA-gene-targeted denaturing gradient gel electrophoresis (DGGE) fingerprinting was conducted. Cloning and sequencing of partial 16S rRNA fragments were performed on both low nitrogen basal and methanogenic media enrichments. Phylogenetic analysis revealed similar homologies to eight different bacterial and one archaeal genera classified under the phyla Firmicutes, Actinobacteria, and Euryarchaeota. After continuing enrichment for RDX degraders for 1 year, two consortia remained: one that transformed RDX in 4 days and one which had slowed after 2 months of transfers without RDX. DGGE comparison of the slower transforming consortium to the faster one showed identical banding patterns except one band. Homology matches to clones from the two consortia identified the same uncultured Clostridia genus in both; Sporanaerobacter

  18. Polar switching in trialkylbenzene-1,3,5-tricarboxamides.

    Science.gov (United States)

    Fitié, Carel F C; Roelofs, W S Christian; Magusin, Pieter C M M; Wübbenhorst, Michael; Kemerink, Martijn; Sijbesma, Rint P

    2012-04-01

    The hydrogen-bonded hexagonal columnar LC (Col(hd)) phases formed by benzene-1,3,5-tricarboxamide (BTA) derivatives can be aligned uniformly by an electric field and display switching behavior with a high remnant polarization. The polar switching in three symmetrically substituted BTAs with alkyl chains varying in length between 6 and 18 carbon atoms (C6, C10, and C18) was investigated by electro-optical switching experiments, dielectric relaxation spectroscopy (DRS), and solid-state NMR. The goal was to characterize ferroelectric properties of BTA-based columnar LCs, which display a macroscopic axial dipole moment due to the head-to-tail stacking of hydrogen-bonded amides. The Col(hd) phase of all three BTAs can be aligned uniformly by a dc field ∼30 V/μm. Moreover, C10 and C18 display extrinsic polar switching characterized by a remnant polarization and coercive field of 1-2 μC/cm(2) and 20-30 V/μm, respectively. In the absence of an external field, the polarization is lost in 1-1000 s, depending on device details and temperature. DRS revealed a columnar glass transition in the low-temperature region of the LC phase related to collective vibrations in the hydrogen-bonded columns that freeze out below 41-54 °C. At higher temperatures, a relaxation process is present originating from the collective reorientation of amide groups along the column axis (inversion of the macrodipole). Matching activation energies suggest that the molecular mechanism underlying the polar switching and the R-processes is identical. These results illustrate that LC phases based on BTAs offer the unique possibility to integrate polarization with other functionalities in a single nanostructured material.

  19. Vibrational spectra of 3,5-dimethylpyrazole and deuterated derivatives.

    Science.gov (United States)

    Orza, J M; García, M V; Alkorta, I; Elguero, J

    2000-07-01

    The infrared (IR) and Raman spectra of 3,5-dimethylpyrazole have been recorded in the vapor, liquid (melt and solution) and solid states. Two deuterated derivatives, C5H7N-ND and C5D7N-NH, were also studied in solid state and in solutions. Instrumental resolution was relatively low, 2.0 cm(-1) in the IR and approximately 2.7 cm(-1) in the Raman spectra. The solids are made of cyclic hydrogen-bonded trimers. These trimers, present also in chloroform and acetone solutions, give rise to characteristic high absorption IR spectra in the 3200-2500 cm(-1) region, related to Fermi resonance involving nu(NH) vibrations. Bands from trimers are not present in water solutions but these solutions show spectral features similar in several ways to those of the trimer, attributable to solvent-bonded complexes. Evidence of H-bonding interactions with the other solvents is also visible in the high-frequency region. The two very intense bands in the Raman spectra of the solids appearing at 115 and 82 cm(-1) in the parent compound are also connected with a trimer formation. To interpret the experimental data, ab initio computations of the harmonic vibrational frequencies and IR and Raman intensities were carried out using the Gaussian 94 program package after full optimization at the RHF/6-31G* level for the three monomeric compounds as well as for three models of the trimer, with C3h, C3 and C1 symmetry. The combined use of experiments and computations allow a firm assignment of most of the observed bands for all the systems. In general, the agreement between theory and experiment is very good, with the exception of the IR and Raman intensities of some transitions. Particularly noticeable is the failure of the theoretical calculation in accounting for the high intensity of the Raman bands of the solid about 115 and 82 cm(-1).

  20. Ozone production efficiency of a ship-plume: ITCT 2K2 case study.

    Science.gov (United States)

    Kim, Hyun S; Kim, Yong H; Han, Kyung M; Kim, Jhoon; Song, Chul H

    2016-01-01

    Ozone production efficiency (OPE) of ship plume was first evaluated in this study, based on ship-plume photochemical/dynamic model simulations and the ship-plume composition data measured during the ITCT 2K2 (Intercontinental Transport and Chemical Transformation 2002) aircraft campaign. The averaged instantaneous OPEs (OPE(i)‾) estimated via the ship-plume photochemical/dynamic modeling for the ITCT 2K2 ship-plume ranged between 4.61 and 18.92, showing that the values vary with the extent of chemical evolution (or chemical stage) of the ship plume and the stability classes of the marine boundary layer (MBL). Together with OPE(i)‾, the equivalent OPEs (OPE(e)‾) for the entire ITCT 2K2 ship-plume were also estimated. The OPE(e)‾ values varied between 9.73 (for the stable MBL) and 12.73 (for the moderately stable MBL), which agreed well with the OPE(e)‾ of 12.85 estimated based on the ITCT 2K2 ship-plume observations. It was also found that both the model-simulated and observation-based OPE(e)‾ inside the ship-plume were 0.29-0.38 times smaller than the OPE(e)‾ calculated/measured outside the ITCT 2K2 ship-plume. Such low OPEs insides the ship plume were due to the high levels of NO and non-liner ship-plume photochemistry. Possible implications of this ship-plume OPE study in the global chemistry-transport modeling are also discussed.

  1. VizieR Online Data Catalog: K2 EPIC stellar properties for 138600 targets (Huber+, 2016)

    Science.gov (United States)

    Huber, D.; Bryson, S. T.; Haas, M. R.; Barclay, T.; Barentsen, G.; Howell, S. B.; Sharma, S.; Stello, D.; Thompson, S. E.

    2016-06-01

    The K2 Mission uses the Kepler spacecraft to obtain high-precision photometry over ~80 day campaigns in the ecliptic plane. The Ecliptic Plane Input Catalog (EPIC) provides coordinates, photometry, and kinematics based on a federation of all-sky catalogs to support target selection and target management for the K2 mission. We describe the construction of the EPIC, as well as modifications and shortcomings of the catalog. Kepler magnitudes (Kp) are shown to be accurate to ~0.1mag for the Kepler field, and the EPIC is typically complete to Kp~17 (Kp~19 for campaigns covered by Sloan Digital Sky Survey). We furthermore classify 138600 targets in Campaigns 1-8 (~88% of the full target sample) using colors, proper motions, spectroscopy, parallaxes, and galactic population synthesis models, with typical uncertainties for G-type stars of ~3% in Teff, ~0.3dex in logg~40% in radius, ~10% in mass, and ~40% in distance. Our results show that stars targeted by K2 are dominated by K-M dwarfs (~41% of all selected targets), F-G dwarfs (~36%), and K giants (~21%), consistent with key K2 science programs to search for transiting exoplanets and galactic archeology studies using oscillating red giants. However, we find significant variation of the fraction of cool dwarfs with galactic latitude, indicating a target selection bias due to interstellar reddening and increased contamination by giant stars near the galactic plane. We discuss possible systematic errors in the derived stellar properties, and differences with published classifications for K2 exoplanet host stars. (1 data file).

  2. 197 Candidates and 104 Validated Planets in K2’s First Five Fields

    Science.gov (United States)

    Crossfield, Ian J. M.; Ciardi, David R.; Petigura, Erik A.; Sinukoff, Evan; Schlieder, Joshua E.; Howard, Andrew W.; Beichman, Charles A.; Isaacson, Howard; Dressing, Courtney D.; Christiansen, Jessie L.; Fulton, Benjamin J.; Lépine, Sébastien; Weiss, Lauren; Hirsch, Lea; Livingston, John; Baranec, Christoph; Law, Nicholas M.; Riddle, Reed; Ziegler, Carl; Howell, Steve B.; Horch, Elliott; Everett, Mark; Teske, Johanna; Martinez, Arturo O.; Obermeier, Christian; Benneke, Björn; Scott, Nic; Deacon, Niall; Aller, Kimberly M.; Hansen, Brad M. S.; Mancini, Luigi; Ciceri, Simona; Brahm, Rafael; Jordán, Andrés; Knutson, Heather A.; Henning, Thomas; Bonnefoy, Michaël; Liu, Michael C.; Crepp, Justin R.; Lothringer, Joshua; Hinz, Phil; Bailey, Vanessa; Skemer, Andrew; Defrere, Denis

    2016-09-01

    We present 197 planet candidates discovered using data from the first year of the NASA K2 mission (Campaigns 0-4), along with the results of an intensive program of photometric analyses, stellar spectroscopy, high-resolution imaging, and statistical validation. We distill these candidates into sets of 104 validated planets (57 in multi-planet systems), 30 false positives, and 63 remaining candidates. Our validated systems span a range of properties, with median values of R P = 2.3 {R}\\oplus , P = 8.6 days, {T}{eff} = 5300 K, and Kp = 12.7 mag. Stellar spectroscopy provides precise stellar and planetary parameters for most of these systems. We show that K2 has increased by 30% the number of small planets known to orbit moderately bright stars (1-4 R ⊕, Kp = 9-13 mag). Of particular interest are 76 planets smaller than 2 R ⊕, 15 orbiting stars brighter than Kp = 11.5 mag, 5 receiving Earth-like irradiation levels, and several multi-planet systems—including 4 planets orbiting the M dwarf K2-72 near mean-motion resonances. By quantifying the likelihood that each candidate is a planet we demonstrate that our candidate sample has an overall false positive rate of 15%-30%, with rates substantially lower for small candidates (\\lt 2{R}\\oplus ) and larger for candidates with radii \\gt 8{R}\\oplus and/or with P\\lt 3 {{days}}. Extrapolation of the current planetary yield suggests that K2 will discover between 500 and 1000 planets in its planned four-year mission, assuming sufficient follow-up resources are available. Efficient observing and analysis, together with an organized and coherent follow-up strategy, are essential for maximizing the efficacy of planet-validation efforts for K2, TESS, and future large-scale surveys.

  3. Influence of the training loading on the program paralympic junior sport school on the indexes of physical qualities of young tennis players 6-8 years

    Directory of Open Access Journals (Sweden)

    Loboda V.S.

    2012-04-01

    Full Text Available Influence of the training loading is considered on the program paralympic junior sport school on the indexes of physical qualities of young tennis players 6-8 years. The aim of experiment was an exposure of dynamics of development of motive internalss of young tennis players during three years (6-8 years under the influence of the training loading on the program of children sport school. In experiment took part the group of initial preparation in an amount 25 children (boys. Research was conducted within the framework of the operative (employments, current (mezocycle and stage (annual planning of training process.

  4. Particulate matter chemistry and dynamics in the twilight zone at VERTIGO ALOHA and K2 sites

    Science.gov (United States)

    Bishop, James K. B.; Wood, T. J.

    2008-12-01

    Understanding particle dynamics in the 'Twilight Zone' is critical to prediction of the ocean's carbon cycle. As part of the VERtical Transport In the Global Ocean (VERTIGO) project, this rarely sampled regime extending from the base of the euphotic layer to 1000 m, was characterized by double-paired day/night Multiple Unit Large Volume in-situ Filtration System (MULVFS) deployments and by ˜100 high-frequency CTD/transmissometer/turbidity sensor profiles. VERTIGO studies lasting 3 weeks, contrasted oligotrophic station ALOHA (22.75°N 158°W), sampled in June-July 2004, with a biologically productive location (47 °N 161°E) near station K2 in the Oyashio, occupied July-August 2005. Profiles of major and minor particulate components (C org, N, P, Ca, Si, Sr, Ba, Mn) in 51 μm size fractions, in-water optics, neutrally buoyant sediment trap (NBST) fluxes, and zooplankton data were intercompared. MULVFS total C org and C-Star particle beam attenuation coefficient ( C P) were consistently related at both sites with a 27 μM m -1 conversion factor. At K2, C P profiles further showed a multitude of transient spikes throughout the water column and spike abundance profiles closely paralleled the double peaked abundance profiles of zooplankton. Also at K2, copepods contributed ˜40% and 10%, night and day, respectively to >51 μm C org of MULVFS samples in the mixed layer, but few copepods were collected in deeper waters; however, non-swimming radiolarians were quantitatively sampled. A recent hypothesis regarding POC differences between pumps and bottles is examined in light of these results. Particulate >51 μm C org, N, and P at both ALOHA and K2 showed strong attenuation with depth at both sites. Notable at ALOHA were unusually high levels of >51 μm Sr (up to 4 nM) in the mixed layer, a reflection of high abundances of SrSO 4 precipitating Acantharia. Notable at K2 were major changes in water column inventories of many particulate components to 700 m over 10 days

  5. Particulate matter chemistry and dynamics in the Twilight Zone at VERTIGO ALOHA and K2 Sites

    Energy Technology Data Exchange (ETDEWEB)

    Bishop, James K.B.; Wood, T.J.

    2008-03-25

    Understanding particle dynamics in the 'Twilight Zone' is critical to prediction of the ocean's carbon cycle. As part of the VERTIGO (VERtical Transformations In the Global Ocean) project, this rarely sampled regime extending from the base of the euphotic layer to 1000 m, was characterized by double-paired day/night Multiple Unit Large Volume in-situ Filtration System (MULVFS) deployments and by {approx}100 high-frequency CTD/transmissometer/turbidity sensor profiles. VERTIGO studies lasting three weeks, contrasted oligotrophic station ALOHA (22.75{sup o}N 158{sup o}W), sampled in June-July 2004, with a biologically productive location (47{sup o}N 161{sup o}E) near station K2 in the Oyashio, occupied July-August 2005. Profiles of major and minor particulate components (C{sub org}, N, P, Ca, Si, Sr, Ba, Mn) in <1, 1-51, and >51 {micro}m size fractions, in-water optics, neutrally buoyant sediment trap (NBST) fluxes, and zooplankton data were intercompared. MULVFS total C{sub org} and C-Star particle beam attenuation coefficient (C{sub P}) were consistently related at both sites with a 27 {micro}M m{sup -1} conversion factor. 26 At K2, C{sub P} profiles further showed a multitude of transient spikes throughout the water column and spike abundance profiles closely paralleled the double peaked abundance profiles of zooplankton. Also at K2, copepods contributed {approx}40% and 10%, night and day, respectively to >51 {micro}m C{sub org} of MULVFS samples in the mixed layer, but few copepods were collected in deeper waters; however, non-swimming radiolarians were quantitatively sampled. A recent hypothesis regarding POC differences between pumps and bottles is examined in light of these results. Particulate >51 {micro}m C{sub org}, N, and P at both ALOHA and K2 showed strong attenuation with depth at both sites. Notable at ALOHA were unusually high levels of >51 {micro}m Sr (up to 4 nM) in the mixed layer, a reflection of high abundances of SrSO{sub 4

  6. Quantifying the surface subsurface biogeochemical coupling during the VERTIGO ALOHA and K2 studies

    Science.gov (United States)

    Boyd, Philip W.; Gall, Mark P.; Silver, Mary W.; Coale, Susan L.; Bidigare, Robert R.; Bishop, James L. K. B.

    2008-07-01

    A central question addressed by the VERtical Transport In the Global Ocean (VERTIGO) study was 'What controls the efficiency of particle export between the surface and subsurface ocean'? Here, we present data from sites at ALOHA (N Central Pacific Gyre) and K2 (NW subarctic Pacific) on phytoplankton processes, and relate them via a simple planktonic foodweb model, to subsurface particle export (150-500 m). Three key factors enable quantification of the surface-subsurface coupling: a sampling design to overcome the temporal lag and spatial displacement between surface and subsurface processes; data on the size partitioning of net primary production (NPP) and subsequent transformations prior to export; estimates of the ratio of algal- to faecal-mediated vertical export flux. At ALOHA, phytoplankton were characterized by low stocks, NPP, Fv/ Fm (N-limited), and were dominated by picoplankton. The HNLC waters at K2 were characterized by both two-fold changes in NPP and floristic shifts (high to low proportion of diatoms) between deployment 1 and 2. Prediction of export exiting the euphotic zone was based on size partitioning of NPP, a copepod-dominated foodweb and a ratio of 0.2 (ALOHA) and 0.1 (K2) for algal:faecal particle flux. Predicted export was 20-22 mg POC m -2 d -1 at ALOHA (i.e. 10-11% NPP (0-125 m); 1.1-1.2×export flux at 150 m ( E150). At K2, export was 111 mg C m -2 d -1 (21% NPP (0-50 m); 1.8× E150) and 33 mg POC m -2 d -1 (11% NPP, 0-55 m); 1.4× E150) for deployments 1 and 2, respectively. This decrease in predicted export at K2 matches the observed trend for E150. Also, the low attenuation of export flux from 60 to 150 m is consistent with that between 150 and 500 m. This strong surface-subsurface coupling suggests that phytoplankton productivity and floristics play a key role at K2 in setting export flux, and moreover that pelagic particle transformations by grazers strongly influence to what extent sinking particles are further broken down in the

  7. Quantifying the surface-subsurface biogeochemical coupling during the VERTIGO ALOHA and K2 studies

    Energy Technology Data Exchange (ETDEWEB)

    Boyd, P.W.; Gall, M.P.; Silver, M.W.; Bishop, J.K.B.; Coale, Susan L.; Bidigare, Robert R.

    2008-02-25

    A central question addressed by the VERTIGO (VERtical Transport In the Global Ocean) study was 'What controls the efficiency of particle export between the surface and subsurface ocean'? Here, we present data from sites at ALOHA (N Central Pacific Gyre) and K2 (NW subarctic Pacific) on phytoplankton processes, and relate them via a simple planktonic foodweb model, to subsurface particle export (150-500 m). Three key factors enable quantification of the surface-subsurface coupling: a sampling design to overcome the temporal lag and spatial displacement between surface and subsurface processes; data on the size-partitioning of Net Primary Production (NPP) and subsequent transformations prior to export; estimates of the ratio of algal- to faecal-mediated vertical export flux. At ALOHA, phytoplankton were characterized by low stocks, NPP, F{sub v}/F{sub m} (N-limited), and were dominated by picoplankton. The HNLC waters at K2 were characterized by both two-fold changes in NPP and floristic shifts (high to low proportion of diatoms) between deployment 1 and 2. Prediction of export exiting the euphotic zone was based on size-partitioning of NPP, a copepod-dominated foodweb and a ratio of 0.2 (ALOHA) and 0.1 (K2) for algal:faecal particle flux. Predicted export was 20-22 mg POC m{sup -2} d{sup -1} at ALOHA (i.e. 10-11% NPP (0-125 m); 1.1-1.2 x export flux at 150 m (E{sub 150}). At K2, export was 111 mg C m{sup -2} d{sup -1} (21% NPP (0-50 m); 1.8 x E{sub 150}) and 33 mg POC m{sup -2} d{sup -1} (11% NPP, 0-55 m); 1.4 x E{sub 150}) for deployments 1 and 2, respectively. This decrease in predicted export at K2 matches the observed trend for E{sub 150}. Also, the low attenuation of export flux from 60 to 150 m is consistent with that between 150 to 500 m. This strong surface-subsurface coupling suggests that phytoplankton productivity and floristics play a key role at K2 in setting export flux, and moreover that pelagic particle transformations by grazers strongly

  8. Genetic and antigenic characteristics of ApxIIA and ApxIIIA from Actinobacillus pleuropneumoniae serovars 2, 3, 4, 6, 8 and 15.

    Science.gov (United States)

    To, Ho; Nagai, Shinya; Iwata, Akira; Koyama, Tomohiro; Oshima, Atsushi; Tsutsumi, Nobuyuki

    2016-07-01

    Apx toxins produced by Actinobacillus pleuropneumoniae are essential components of new generation vaccines. In this study, apxIIA and apxIIIA genes of serovars 2, 3, 4, 6, 8 and 15 were cloned and sequenced. Amino acid sequences of ApxIIA proteins of serovars 2, 3, 4, 6, 8 and 15 were almost identical to those of serovars 1, 5, 7, 9 and 11-13. Immunoblot analysis showed that rApxIIA from serovars 2 and 15 reacts strongly with sera from animals infected with various serovars. Sequence analysis revealed that ApxIIIA proteins has two variants, one in strains of serovar 2 and the other in strains of serovars 3, 4, 6, 8 and 15. A mouse cross-protection study showed that mice actively immunized with rApxIIIA/2 or rApxIIIA/15 are protected against challenge with A. pleuropneumoniae strains of serovars 3, 4, 6, 8, 15, and 2 expressing ApxIII/15 and ApxIII/2, respectively. Similarly, mice passively immunized with rabbit anti-rApxIIIA/2 or anti-rApxIIIA/15 sera were found to be protected against challenge with strains of serovars 2 and 15. Our study revealed antigenic and sequence similarities within ApxIIA and ApxIIIA proteins, which may help in the development of effective vaccines against disease caused by A. pleuropneumoniae. © 2016 The Societies and John Wiley & Sons Australia, Ltd.

  9. Relationship between Executive Functioning and Symptoms of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in 6-8 Year Old Children

    Science.gov (United States)

    Neely, Rachel Jane; Green, Jessica Leigh; Sciberras, Emma; Hazell, Philip; Anderson, Vicki

    2016-01-01

    This study examined relationships between executive functioning (EF) and ADHD/ASD symptoms in 339 6-8 year-old children to characterise EF profiles associated with ADHD and ADHD + ASD. ADHD status was assessed using screening surveys and diagnostic interviews. ASD symptoms were measured using the Social Communication Questionnaire, and children…

  10. Metacognitive and language-specific knowledge in native and foreign language reading comprehension: an emprical study among Dutch students in grades 6, 8 and 10

    NARCIS (Netherlands)

    Schoonen, R.; Hulstijn, J.; Bossers, B.

    1998-01-01

    This article gives the results of a study among 685 students in grades 6, 8 and 10 in the Netherlands to whom we administered grade-appropriate measures of reading comprehension and vocabulary knowledge in their native language (NL), Dutch, as well as, in grades 8 and 10, in English as a foreign lan

  11. Metacognitive and language-specific knowledge in native and foreign language reading comprehension: an emprical study among Dutch students in grades 6, 8 and 10

    NARCIS (Netherlands)

    Schoonen, R.; Hulstijn, J.; Bossers, B.

    1998-01-01

    This article gives the results of a study among 685 students in grades 6, 8 and 10 in the Netherlands to whom we administered grade-appropriate measures of reading comprehension and vocabulary knowledge in their native language (NL), Dutch, as well as, in grades 8 and 10, in English as a foreign lan

  12. New Biosynthetic Step in the Melanin Pathway of Wangiella (Exophiala) dermatitidis: Evidence for 2-Acetyl-1,3,6,8-Tetrahydroxynaphthalene as a Novel Precursor

    Science.gov (United States)

    The predominant cell wall melanin of Wangiella dermatitidis, a black fungal pathogen of humans, is synthesized from 1,8-dihydroxynaphthalene (D2HN). An early precursor, 1,3,6,8-tetrahydroxynaphthalene (T4HN), in the pathway leading to D2HN is reportedly produced as a pentaketide directly by an iter...

  13. easyCBM CCSS Math Item Scaling and Test Form Revision (2012-2013): Grades 6-8. Technical Report #1313

    Science.gov (United States)

    Anderson, Daniel; Alonzo, Julie; Tindal, Gerald

    2012-01-01

    The purpose of this technical report is to document the piloting and scaling of new easyCBM mathematics test items aligned with the Common Core State Standards (CCSS) and to describe the process used to revise and supplement the 2012 research version easyCBM CCSS math tests in Grades 6-8. For all operational 2012 research version test forms (10…

  14. Comparing Ullmann Coupling on Noble Metal Surfaces: On-Surface Polymerization of 1,3,6,8-Tetrabromopyrene on Cu(111) and Au(111)

    DEFF Research Database (Denmark)

    Pham, Tuan Anh; Song, Fei; Nguyen, Manh-Thuong;

    2016-01-01

    The on-surface polymerization of 1,3,6,8-tetrabromopyrene (Br4Py) on Cu(111) and Au(111) surfaces under ultrahigh vacuum conditions was investigated by a combination of scanning tunneling microscopy (STM), X-ray photoelectron spectroscopy (XPS) and density functional theory (DFT) calculations...

  15. Research on Relationship of Spatial Visualization and Confidence to Male/Female Mathematics Achievement in Grades 6-8. Final Report.

    Science.gov (United States)

    Fennema, Elizabeth

    Reported are two separate but related longitudinal studies of two variables strongly associated with sex-related differences in mathematics achievement and enrollment, namely spatial visualization and confidence in learning mathematics. First, boys (N=33) and girls (N=36) in grades 6-8 who were discrepant in their spatial and verbal skills were…

  16. Immunosuppression for 6-8 weeks after modified donor lymphocyte infusion reduced acute graft-versus-host disease without influencing graft-versus-leukemia effect in haploidentical transplant

    Institute of Scientific and Technical Information of China (English)

    Yan Chenhua; Xu Lanping; Liu Daihong; Chen Huan; Wang Yu; Liu Kaiyan; Huang Xiaojun

    2014-01-01

    Background In haploidentical hematopoietic stem cell transplantation (HSCT),the duration of graft-versus-host disease (GVHD) prophylaxis after modified donor lymphocyte infusion (DLI) was the only risk factor of DLI-associated grades 3-4 acute GVHD.However,the successful application of modified DLI depended not only on the reduction of severe GVHD,but also on the preservation of graft-versus-leukemia (GVL) effect.Therefore,this study was performed to compare the impact of prophylaxis for 6-8 weeks and prophylaxis for <6 weeks on GVL effect after modified DLI in haploidentical HSCT.Methods A total of 103 consecutive patients developing hematological relapse or minimal residual disease (MRD)-positive status after haploidentical HSCT and receiving modified DLI were investigated retrospectively.Fifty-two patients received prophylaxis for 6-8 weeks after modified DLI; the remaining 51 patients received prophylaxis for <6 weeks.Results First,compared with prophylaxis for <6 weeks,prophylaxis for 6-8 weeks reduced incidence of relapse in total patients (26.6% vs.69.0%,P <0.001).Besides,prophylaxis for 6-8 weeks also reduced incidence of relapse in 54 patients developing hematological relapse post-transplant (P=0.018) and in 49 patients developing MRD-positive status post-transplant (P <0.001).Second,prophylaxis for 6-8 weeks reduced incidence of acute GVHD (P <0.05),reduced the therapeutic application of immunosuppressive agents (P=0.019),but increased the incidence of chronic GVHD (P<0.05).Third,prophylaxis for 6-8 weeks improved overall survival and disease-free survival in total patients,as well as in patients developing hematological relapse post-transplant and in patients developing MRD-positive status post-transplant (P <0.05).Conclusions In haploidentical HSCT,prophylaxis for 6-8 weeks after modified DLI does not reduce GVL effect,but reduces the incidence of DLI-associated acute GVHD compared with prophylaxis for <6 weeks.This strategy will

  17. Selective formation of tetrahedral Pt nanocrystals from K2PtCl6/PVP

    Institute of Scientific and Technical Information of China (English)

    YU Yingtao; XU Boqing

    2003-01-01

    Tetrahedral platinum (Pt) nanocrystals (3-8 nm) are synthesized in high selectivity (ca. 80%) from hydrogen reduction of aqueous K2PtCl6 by using polyvinylpyrrolidone (PVP: Mw≈360000) as a protector. Morphology (TEM) measurements of the metal colloids and UV-Vis absorption of the colloidal solution are employed to monitor the tetrahedron formation during the syntheses with varying K2PtCl6/PVP ratios. The results clearly show a two-stage process for the selective formation of tetrahedral nanocrystals. Rapid nucleation and crystal formation at the early stage result in round-like crystallites and the external facet evolution in thereafter slow crystal growth leads selectively to the formation of the tetrahedrons.

  18. Evolving role of vitamin K2-7(Menaquinone in Osteoporosis & cardiovascular health

    Directory of Open Access Journals (Sweden)

    Faruqui A.Ahmad M Asrar A

    2014-04-01

    Full Text Available Osteoporosis & cardiovascular disorders are one of the commonest global problem. These two disorders not only affect the quality of life but also put a huge financial burden on the family and the nation as a whole. Since ages we have been using calcium supplements for the management of osteoporosis and the recent reports have shown that it can lead to increased cardiovascular complications. Vitamin K2 ,an age old vitamin has been shown to take care of osteoporosis and cardiovascular complications, since it plays an important role in carboxylation of certain proteins in bone and blood vessel. This review article summarizes the ­­role of vitamin K2 in osteoporosis 7 cardiovascular disorders and also throws light on the clinical evidences available for the same.

  19. Planetary Candidates from the First Year of the K2 Mission

    CERN Document Server

    Vanderburg, Andrew; Buchhave, Lars A; Bieryla, Allyson; Berlind, Perry; Calkins, Michael L; Esquerdo, Gilbert A; Welsh, Sophie; Johnson, John Asher

    2015-01-01

    The Kepler Space Telescope is currently searching for planets transiting stars along the ecliptic plane as part of its extended K2 mission. We processed the publicly released data from the first year of K2 observations (Campaigns 0, 1, 2, and 3) and searched for periodic eclipse signals consistent with planetary transits. Out of 59,174 targets we searched, we detect 234 planetary candidates around 208 stars. These candidates range in size from gas giants to smaller than the Earth, and range in orbital periods from hours to over a month. We conducted initial reconnaissance spectroscopy of 68 of the brighter candidate host stars, and present high resolution optical spectra for these stars. We make all of our data products, including light curves, spectra, and vetting diagnostics available to users online.

  20. A systematic search for transiting planets in the K2 data

    CERN Document Server

    Foreman-Mackey, Daniel; Hogg, David W; Morton, Timothy D; Wang, Dun; Schölkopf, Bernhard

    2015-01-01

    Photometry of stars from the K2 extension of NASA's Kepler mission is afflicted by systematic effects caused by small (few-pixel) drifts in the telescope pointing and other spacecraft issues. We present a method for searching K2 light curves for evidence of exoplanets by simultaneously fitting for these systematics and the transit signals of interest. This method is more computationally expensive than standard search algorithms but we demonstrate that it can be efficiently implemented and used to discover transit signals. We apply this method to the full Campaign 1 dataset and report a list of 36 planet candidates transiting 31 stars, along with an analysis of the pipeline performance and detection efficiency based on artificial signal injections and recoveries. For all planet candidates, we present posterior distributions on the properties of each system based strictly on the transit observables.

  1. The K2 Galactic Archaeology Program Data Release 1: Asteroseismic results from Campaign 1

    CERN Document Server

    Stello, D; Elsworth, Y; Garcia, R A; Kallinger, T; Mathur, S; Mosser, B; Sharma, S; Chaplin, W J; Davies, G; Huber, D; Jones, C D; Miglio, A; Aguirre, V S

    2016-01-01

    NASA's K2 mission is observing tens of thousands of stars along the ecliptic, providing data suitable for large scale asteroseismic analyses to inform galactic archaeology studies. Its first campaign covered a field near the north galactic cap, a region never covered before by large asteroseismic-ensemble investigations, and was therefore of particular interest for exploring this part of our Galaxy. Here we report the asteroseismic analysis of all stars selected by the K2 Galactic Archaeology Program during the mission's "North Galactic Cap" campaign 1. Our consolidated analysis uses six independent methods to measure the global seismic properties, in particular the large frequency separation, and the frequency of maximum power. From the full target sample of 8630 stars we find about 1200 oscillating red giants, a number comparable with estimates from galactic synthesis modeling. Thus, as a valuable by-product we find roughly 7500 stars to be dwarfs, which provide a sample well suited for galactic exoplanet o...

  2. First observations of W Virginis stars with K2: detection of period doubling

    Science.gov (United States)

    Plachy, E.; Molnár, L.; Jurkovic, M. I.; Smolec, R.; Moskalik, P. A.; Pál, A.; Szabados, L.; Szabó, R.

    2017-02-01

    We present the first analysis of W Vir stars observed by the Kepler space telescope in the K2 mission. Clear cycle-to-cycle variation were detected in the light curves of KT Sco and the globular cluster member M80-V1. While the variations in the former star seems to be irregular on the short time scale of the K2 data, the latter appears to experience period doubling in its pulsation. Ground-based colour data confirmed that both stars are W Vir-type pulsators, while a comparison with historical photometric time-series data revealed drastic period changes in both stars. For comparison we reexamine ground-based observations of W Vir, the prototype of the class, and conclude that it shows period doubling instead of mode beating. These results support the notion that nonlinear dynamics plays an important role in the pulsation of W Virginis-type stars.

  3. VizieR Online Data Catalog: K2 Campaign 9 added events (Henderson+, 2016)

    Science.gov (United States)

    Henderson, C. B.; Poleski, R.; Penny, M.; Street, R. A.; Bennett, D. P.; Hogg, D. W.; Gaudi B. S.; K2 Campaign 9 Microlensing Science Team; Zhu, W.; Barclay, T.; Barentsen, G.; Howell, S. B.; Mullally, F.; Udalski, A.; Szymanski, M. K.; Skowron, J.; Mroz, P.; Kozlowski, S.; Wyrzykowski, L.; Pietrukowicz, P.; Soszynski, I.; Ulaczyk, K.; Pawlak, M.; Ogle Project; Sumi, T.; Abe, F.; Asakura, Y.; Barry, R. K.; Bhattacharya, A.; Bond, I. A.; Donachie, M.; Freeman, M.; Fukui, A.; Hirao, Y.; Itow, Y.; Koshimoto, N.; Li, M. C. A.; Ling, C. H.; Masuda, K.; Matsubara, Y.; Muraki, Y.; Nagakane, M.; Ohnishi, K.; Oyokawa, H.; Rattenbury, N.; Saito, T.; Sharan, A.; Sullivan, D. J.; Tristram, P. J.; Yonehara, A.; Moa Collaboration; Bachelet, E.; Bramich, D. M.; Cassan, A.; Dominik, M.; Jaimes, R. F.; Horne, K.; Hundertmark, M.; Mao, S.; Ranc, C.; Schmidt, R.; Snodgrass, C.; Steele, I. A.; Tsapras, Y.; Wambsganss, J.; Robonet Project; Bozza, V.; Burgdorf, M. J.; Jorgensen, U. G.; Novati, S. C.; Ciceri, S.; D'Ago, G.; Evans, D. F.; Hessman, F. V.; Hinse, T. C.; H! Usser T.-, O.; Mancini, L.; Popovas, A.; Rabus, M.; Rahvar, S.; Scarpetta, G.; Skottfelt, J.; Southworth, J.; Unda-Sanzana E.; Mindstep Team; Bryson, S. T.; Caldwell, D. A.; Haas, M. R.; Larson, K.; McCalmont, K.; Packard, M.; Peterson, C.; Putnam, D.; Reedy, L.; Ross, S.; van Cleve J. E.; K2C9 Engineering Team; Akeson, R.; Batista, V.; Beaulieu, J.-P.; Beichman, C. A.; Bryden, G.; Ciardi, D.; Cole, A.; Coutures, C.; Foreman-Mackey, D.; Fouque, P.; Friedmann, M.; Gelino, C.; Kaspi, S.; Kerins, E.; Korhonen, H.; Lang, D.; Lee, C.-H.; Lineweaver, C. H.; Maoz, D.; Marquette, J.-B.; Mogavero, F.; Morales, J. C.; Nataf, D.; Pogge, R. W.; Santerne, A.; Shvartzvald, Y.; Suzuki, D.; Tamura, M.; Tisserand, P.; Wang, D.

    2017-08-01

    The deadline for adding events to C9a was 2016 March 1 and for C9b it was 2016 April 25. In total, 34 and 61 ongoing events were added to the target list for C9a and C9b, respectively. Table 2 provides a list of the event names, coordinates, and baseline I-band magnitudes for all of these events, many of which were added to the target list for both halves of K2C9. This resulted in 70 unique events that were added to the target list and for which data were downlinked for at least one half of K2C9. (1 data file).

  4. First observations of W Virginis stars with K2: detection of period doubling

    CERN Document Server

    Plachy, E; Jurkovic, M I; Smolec, R; Moskalik, P A; Pál, A; Szabados, L; Szabó, R

    2016-01-01

    We present the first analysis of W Vir stars observed by the Kepler space telescope in the K2 mission. Clear cycle-to-cycle variation were detected in the light curves of KT Sco and the globular cluster member M80-V1. While the variations in the former star seems to be irregular on the short time scale of the K2 data, the latter appears to experience period doubling in its pulsation. Ground-based colour data confirmed that both stars are W Vir-type pulsators, while a comparison with historical photometric time-series data revealed drastic period changes in both stars. For comparison we reexamine ground-based observations of W Vir, the prototype of the class, and conclude that it shows period doubling instead of mode beating. These results support the notion that nonlinear dynamics plays an important role in the pulsation of W Virginis-type stars.

  5. K2 and MAXI observations of Sco X-1 - Evidence for disc precession?

    CERN Document Server

    Hakala, Pasi; Barclay, Thomas; Charles, Phil

    2015-01-01

    Sco X-1 is the archetypal low mass X-ray binary (LMXB) and the brightest persistent extra-solar X-ray source in the sky. It was included in the K2 Campaign 2 field and was observed continuously for 71 days with 1 minute time resolution. In this paper we report these results and underline the potential of K2 for similar observations of other accreting compact binaries. We reconfirm that Sco X-1 shows a bimodal distribution of optical "high" and "low" states and rapid transitions between them on timescales less than 3 hours (or 0.15 orbits). We also find evidence that this behaviour has a typical systemic timescale of 4.8 days, which we interpret as a possible disc precession period in the system. Finally, we confirm the complex optical vs. X-ray correlation/anticorrelation behaviour for "high" and "low" optical states respectively.

  6. PLANETARY CANDIDATES FROM THE FIRST YEAR OF THE K2 MISSION

    Energy Technology Data Exchange (ETDEWEB)

    Vanderburg, Andrew; Latham, David W.; Bieryla, Allyson; Berlind, Perry; Calkins, Michael L.; Esquerdo, Gilbert A.; Welsh, Sophie; Johnson, John Asher [Harvard–Smithsonian Center for Astrophysics, 60 Garden St., Cambridge, MA 02138 (United States); Buchhave, Lars A., E-mail: avanderburg@cfa.harvard.edu [Centre for Star and Planet Formation, Natural History Museum of Denmark and Niels Bohr Institute, University of Copenhagen, Øster Voldgade 5-7, DK-1350 Copenhagen K (Denmark)

    2016-01-15

    The Kepler Space Telescope is currently searching for planets transiting stars along the ecliptic plane as part of its extended K2 mission. We processed the publicly released data from the first year of K2 observations (Campaigns 0, 1, 2, and 3) and searched for periodic eclipse signals consistent with planetary transits. Out of the 59,174 targets that we searched, we detect 234 planetary candidates around 208 stars. These candidates range in size from gas giants to smaller than the Earth, and range in orbital periods from hours to over a month. We conducted initial reconnaissance spectroscopy of 68 of the brighter candidate host stars, and present high-resolution optical spectra for these stars. We make all of our data products, including light curves, spectra, and vetting diagnostics available to users online.

  7. Raman Spectroscopy Evidence of 1:1:1 Complex Formation during Dissolution of WO3 in a Melt of K2S2O7: K2SO4

    DEFF Research Database (Denmark)

    Berg, Rolf W.; Ferré, Irene Maijó; Schäffer, Susan Jeanne Cline

    2006-01-01

    Highly inert yellow solid WO3 was found to be soluble in considerable amounts in molten K2S2O7 at elevated temperatures (650 8C), if only similar molar amounts of sulfates were also present. The dissolution reaction of WO3 into a melt consisting of a 1:1 molar mixture of K2S2O7 and K2SO4 was stud...

  8. Raman Spectroscopic Study of Tungsten(VI) Oxosulfato Complexes in WO3–K2S2O7–K2SO4 Molten Mixtures: Stoichiometry, Vibrational Properties and Molecular Structure

    DEFF Research Database (Denmark)

    Paulson, Andreas L.; Kalampounias, Angelos G.; Berg, Rolf W.

    2011-01-01

    The dissolution reaction of WO3 in pure molten K2S2O7 and in molten K2S2O7-K2SO4 mixtures is studied under static equilibrium conditions in the XWO3 0 = 0-0.33 mol fraction range at temperatures up to 860 C. High temperature Raman spectroscopy shows that the dissolution leads to formation of WVI ...

  9. Congruences involving $\\binom{4k}{2k}$ and $\\binom{3k}k$

    OpenAIRE

    Sun, Zhi-Hong

    2011-01-01

    Let $p$ be a prime greater than 3. In the paper we mainly determine $\\sum_{k=0}^{[p/4]}\\binom{4k}{2k}(-1)^k$, $\\sum_{k=0}^{[p/3]}\\binom{3k}k, \\sum_{k=0}^{[p/3]}\\binom{3k}k(-1)^k$ and $\\sum_{k=0}^{[p/3]}\\binom{3k}k(-3)^k$ modulo $p$, where $[x]$ is the greatest integer not exceeding $x$.

  10. Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health

    OpenAIRE

    Maresz, Katarzyna

    2015-01-01

    Inadequate calcium intake can lead to decreased bone mineral density, which can increase the risk of bone fractures. Supplemental calcium promotes bone mineral density and strength and can prevent osteoporosis. Recent scientific evidence, however, suggests that elevated consumption of calcium supplements may raise the risk for heart disease and can be connected with accelerated deposit of calcium in blood-vessel walls and soft tissues. In contrast, vitamin K2 is associated with the inhibition...

  11. Neutrino induced pion production at MiniBooNE and K2K energies

    CERN Document Server

    Leitner, T; Mosel, U; Alvarez-Ruso, L

    2009-01-01

    We investigate charged and neutral current neutrino-induced incoherent pion production off nuclei within the GiBUU model at energies relevant for the MiniBooNE and K2K experiments. Special attention is paid to the entanglement between measured CCQE and CC1pi+ cross sections. We further give predictions and compare to recent data measured at MiniBooNE.

  12. Quasi-elastic events and nuclear effects with the K2K Sci-Fi detector

    Energy Technology Data Exchange (ETDEWEB)

    Walter, Christopher W. E-mail: walter@budoe.bu.edu

    2002-11-01

    The near detector complex of the K2K long-baseline neutrino experiment contains a scintillating fiber tracking detector. It is capable of detecting not only the muon but also the outgoing proton in neutrino-nucleon scattering. This allows for the enhancement of quasi-elastic interactions in the data sample. However, a proper modeling of the nuclear re-interactions of the proton is necessary to achieve reliable results.

  13. CHARACTERIZING K2 PLANET DISCOVERIES: A SUPER-EARTH TRANSITING THE BRIGHT K DWARF HIP 116454

    Energy Technology Data Exchange (ETDEWEB)

    Vanderburg, Andrew; Montet, Benjamin T.; Johnson, John Asher; Buchhave, Lars A.; Zeng, Li; Latham, David W.; Angus, Ruth; Bieryla, Allyson; Charbonneau, David [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Pepe, Francesco; Udry, Stéphane; Lovis, Christophe [Observatoire Astronomique de l' Université de Genève, 51 chemin des Maillettes, CH-1290 Versoix (Switzerland); Cameron, Andrew Collier [SUPA, School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, Fife KY16 9SS (United Kingdom); Molinari, Emilio; Boschin, Walter [INAF-Fundación Galileo Galilei, Rambla José Ana Fernández Pérez, 7, E-38712 Breña Baja (Spain); Matthews, Jaymie M. [University of British Columbia, Vancouver, BC V6T1Z1 (Canada); Cameron, Chris [Cape Breton University, 1250 Grand Lake Road, Sydney NS B1P 6L2 (Canada); Law, Nicholas [University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 (United States); Bowler, Brendan P. [California Institute of Technology, Pasadena, CA 91125 (United States); Baranec, Christoph, E-mail: avanderburg@cfa.harvard.edu [University of Hawai' i at Mānoa, Hilo, HI 96720 (United States); and others

    2015-02-10

    We report the first planet discovery from the two-wheeled Kepler (K2) mission: HIP 116454 b. The host star HIP 116454 is a bright (V = 10.1, K = 8.0) K1 dwarf with high proper motion and a parallax-based distance of 55.2 ± 5.4 pc. Based on high-resolution optical spectroscopy, we find that the host star is metal-poor with [Fe/H] =–0.16 ± 0.08 and has a radius R {sub *} = 0.716 ± 0.024 R {sub ☉} and mass M {sub *} = 0.775 ± 0.027 M {sub ☉}. The star was observed by the Kepler spacecraft during its Two-Wheeled Concept Engineering Test in 2014 February. During the 9 days of observations, K2 observed a single transit event. Using a new K2 photometric analysis technique, we are able to correct small telescope drifts and recover the observed transit at high confidence, corresponding to a planetary radius of R{sub p} = 2.53 ± 0.18 R {sub ⊕}. Radial velocity observations with the HARPS-N spectrograph reveal a 11.82 ± 1.33 M {sub ⊕} planet in a 9.1 day orbit, consistent with the transit depth, duration, and ephemeris. Follow-up photometric measurements from the MOST satellite confirm the transit observed in the K2 photometry and provide a refined ephemeris, making HIP 116454 b amenable for future follow-up observations of this latest addition to the growing population of transiting super-Earths around nearby, bright stars.

  14. K2S-activated carbons developed from coal and their methane adsorption behaviors

    Science.gov (United States)

    Feng, Yan-Yan; Yang, Wen; Chu, Wei

    2014-10-01

    The main purpose of this work is to prepare various activated carbons by K2S activation of coal with size fractions of 60-80 meshes, and investigate the microporosity development and corresponding methane storage capacities. Raw coal is mixed with K2S powder, and then heated at 750 °C-900 °C for 30 min-150 min in N2 atmosphere to produce the adsorbents. The texture and surface morphology are characterized by a N2 adsorption/desorption isotherm at 77 K and scanning electron microscopy (SEM). The chemical properties of carbons are confirmed by ultimate analysis. The crystal structure and degree of graphitization are tested by X-ray diffraction and Raman spectra. The relationship between sulfur content and the specific surface area of the adsorbents is also determined. K2S activation is helps to bring about better development of pore texture. These adsorbents are microporous materials with textural parameters increasing in a range of specific surface area 72.27 m2/g-657.7 m2/g and micropore volume 0.035 cm3/g-0.334 cm3/g. The ability of activated carbons to adsorb methane is measured at 298 K and at pressures up to 5.0 MPa by a volumetric method. The Langmuir model fits the experimental data well. It is concluded that the high specific surface area and micropore volume of activated carbons do determine methane adsorption capacity. The adsorbents obtained at 800 °C for 90 min with K2S/raw coal mass ratios of 1.0 and 1.2 show the highest methane adsorption capacities amounting to 106.98 mg/g and 106.17 mg/g, respectively.

  15. Comparing BPM suite K2 Blackpearl and IBM Business process manager

    OpenAIRE

    Kosmač, Matjaž

    2012-01-01

    The thesis brings a comparison of two significant BPM tools called K2 Blackpearl and IBM Business Process Manager, also known as Lombardi. At the beginning we had to identify key criteria to evaluate BPM tools and divide them into larger sets. Afterwards we described how the chosen BPM tools fulfill important criteria in each of these sets. We came to the conclusion that both tools are quite similar, both offering similar (basic) functionalities and features, but often in ve...

  16. Results from solar, atmospheric and K2K experiments and future possibilities with T2K

    Indian Academy of Sciences (India)

    Takaaki Kajita

    2006-10-01

    Recent results from solar, reactor, atmospheric and long baseline (K2K) experiments are discussed. With the improved data statistics and analyses, our knowledge on the neutrino masses and mixing angles are steadily improving. T2K is the next generation neutrino oscillation experiment between J-PARC in Tokai and Super-Kamiokande. This experiment will start in 2009. This experiment is expected to improve the current knowledge on the neutrino masses and mixings substantially.

  17. Observation and polarization measurements of B+/- -->phiK1 +/- and B +/- -->phiK2 *+/-.

    Science.gov (United States)

    Aubert, B; Bona, M; Karyotakis, Y; Lees, J P; Poireau, V; Prencipe, E; Prudent, X; Tisserand, V; Garra Tico, J; Grauges, E; Lopez, L; Palano, A; Pappagallo, M; Eigen, G; Stugu, B; Sun, L; Abrams, G S; Battaglia, M; Brown, D N; Cahn, R N; Jacobsen, R G; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; Lynch, G; Osipenkov, I L; Ronan, M T; Tackmann, K; Tanabe, T; Hawkes, C M; Soni, N; Watson, A T; Koch, H; Schroeder, T; Walker, D; Asgeirsson, D J; Fulsom, B G; Hearty, C; Mattison, T S; McKenna, J A; Barrett, M; Khan, A; Teodorescu, L; Blinov, V E; Bukin, A D; Buzykaev, A R; Druzhinin, V P; Golubev, V B; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Todyshev, K Yu; Bondioli, M; Curry, S; Eschrich, I; Kirkby, D; Lankford, A J; Lund, P; Mandelkern, M; Martin, E C; Stoker, D P; Abachi, S; Buchanan, C; Gary, J W; Liu, F; Long, O; Shen, B C; Vitug, G M; Yasin, Z; Zhang, L; Sharma, V; Campagnari, C; Hong, T M; Kovalskyi, D; Mazur, M A; Richman, J D; Beck, T W; Eisner, A M; Flacco, C J; Heusch, C A; Kroseberg, J; Lockman, W S; Schalk, T; Schumm, B A; Seiden, A; Wang, L; Wilson, M G; Winstrom, L O; Cheng, C H; Doll, D A; Echenard, B; Fang, F; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Andreassen, R; Mancinelli, G; Meadows, B T; Mishra, K; Sokoloff, M D; Bloom, P C; Ford, W T; Gaz, A; Hirschauer, J F; Kreisel, A; Nagel, M; Nauenberg, U; Smith, J G; Ulmer, K A; Wagner, S R; Ayad, R; Soffer, A; Toki, W H; Wilson, R J; Altenburg, D D; Feltresi, E; Hauke, A; Jasper, H; Karbach, M; Merkel, J; Petzold, A; Spaan, B; Wacker, K; Kobel, M J; Mader, W F; Nogowski, R; Schubert, K R; Schwierz, R; Sundermann, J E; Volk, A; Bernard, D; Bonneaud, G R; Latour, E; Thiebaux, Ch; Verderi, M; Clark, P J; Gradl, W; Playfer, S; Watson, J E; Andreotti, M; Bettoni, D; Bozzi, C; Calabrese, R; Cecchi, A; Cibinetto, G; Franchini, P; Luppi, E; Negrini, M; Petrella, A; Piemontese, L; Santoro, V; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Finocchiaro, G; Pacetti, S; Patteri, P; Peruzzi, I M; Piccolo, M; Rama, M; Zallo, A; Buzzo, A; Contri, R; Lo Vetere, M; Macri, M M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Chaisanguanthum, K S; Morii, M; Marks, J; Schenk, S; Uwer, U; Klose, V; Lacker, H M; Bard, D J; Dauncey, P D; Nash, J A; Panduro Vazquez, W; Tibbetts, M; Behera, P K; Chai, X; Charles, M J; Mallik, U; Cochran, J; Crawley, H B; Dong, L; Meyer, W T; Prell, S; Rosenberg, E I; Rubin, A E; Gao, Y Y; Gritsan, A V; Guo, Z J; Lae, C K; Denig, A G; Fritsch, M; Schott, G; Arnaud, N; Béquilleux, J; D'Orazio, A; Davier, M; Firmino da Costa, J; Grosdidier, G; Höcker, A; Lepeltier, V; Le Diberder, F; Lutz, A M; Pruvot, S; Roudeau, P; Schune, M H; Serrano, J; Sordini, V; Stocchi, A; Wormser, G; Lange, D J; Wright, D M; Bingham, I; Burke, J P; Chavez, C A; Fry, J R; Gabathuler, E; Gamet, R; Hutchcroft, D E; Payne, D J; Touramanis, C; Bevan, A J; Clarke, C K; George, K A; Di Lodovico, F; Sacco, R; Sigamani, M; Cowan, G; Flaecher, H U; Hopkins, D A; Paramesvaran, S; Salvatore, F; Wren, A C; Brown, D N; Davis, C L; Alwyn, K E; Bailey, D S; Barlow, R J; Barlow, R J; Chia, Y M; Edgar, C L; Lafferty, G D; West, T J; Yi, J I; Anderson, J; Chen, C; Jawahery, A; Roberts, D A; Simi, G; Tuggle, J M; Dallapiccola, C; Li, X; Salvati, E; Saremi, S; Cowan, R; Dujmic, D; Fisher, P H; Koeneke, K; Sciolla, G; Spitznagel, M; Taylor, F; Yamamoto, R K; Zhao, M; Patel, P M; Robertson, S H; Lazzaro, A; Lombardo, V; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Sanders, D A; Summers, D J; Zhao, H W; Simard, M; Taras, P; Viaud, F B; Nicholson, H; De Nardo, G; Lista, L; Monorchio, D; Onorato, G; Sciacca, C; Raven, G; Snoek, H L; Jessop, C P; Knoepfel, K J; LoSecco, J M; Wang, W F; Benelli, G; Corwin, L A; Honscheid, K; Kagan, H; Kass, R; Morris, J P; Rahimi, A M; Regensburger, J J; Sekula, S J; Wong, Q K; Blount, N L; Brau, J; Frey, R; Igonkina, O; Kolb, J A; Lu, M; Rahmat, R; Sinev, N B; Strom, D; Strube, J; Torrence, E; Castelli, G; Gagliardi, N; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Voci, C; del Amo Sanchez, P; Ben-Haim, E; Briand, H; Calderini, G; Chauveau, J; David, P; Del Buono, L; Hamon, O; Leruste, Ph; Ocariz, J; Perez, A; Prendki, J; Gladney, L; Biasini, M; Covarelli, R; Manoni, E; Angelini, C; Batignani, G; Bettarini, S; Carpinelli, M; Cervelli, A; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Morganti, M; Neri, N; Paoloni, E; Rizzo, G; Walsh, J J; Biesiada, J; Lopes Pegna, D; Lu, C; Olsen, J; Smith, A J S; Telnov, A V; Anulli, F; Baracchini, E; Cavoto, G; del Re, D; Di Marco, E; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Jackson, P D; Li Gioi, L; Mazzoni, M A; Morganti, S; Piredda, G; Polci, F; Renga, F; Voena, C; Ebert, M; Hartmann, T; Schröder, H; Waldi, R; Adye, T; Franek, B; Olaiya, E O; Roethel, W; Wilson, F F; Emery, S; Escalier, M; Esteve, L; Gaidot, A; Ganzhur, S F; Hamel de Monchenault, G; Kozanecki, W; Vasseur, G; Yèche, Ch; Zito, M; Chen, X R; Liu, H; Park, W; Purohit, M V; White, R M; Wilson, J R; Allen, M T; Aston, D; Bartoldus, R; Bechtle, P; Benitez, J F; Cenci, R; Coleman, J P; Convery, M R; Dingfelder, J C; Dorfan, J; Dubois-Felsmann, G P; Dunwoodie, W; Field, R C; Gabareen, A M; Gowdy, S J; Graham, M T; Grenier, P; Hast, C; Innes, W R; Kaminski, J; Kelsey, M H; Kim, H; Kim, P; Kocian, M L; Leith, D W G S; Li, S; Lindquist, B; Luitz, S; Luth, V; Lynch, H L; MacFarlane, D B; Marsiske, H; Messner, R; Muller, D R; Neal, H; Nelson, S; O'Grady, C P; Ofte, I; Perazzo, A; Perl, M; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Snyder, A; Su, D; Sullivan, M K; Suzuki, K; Swain, S K; Thompson, J M; Va'vra, J; Wagner, A P; Weaver, M; West, C A; Wisniewski, W J; Wittgen, M; Wright, D H; Wulsin, H W; Yarritu, A K; Yi, K; Young, C C; Ziegler, V; Burchat, P R; Edwards, A J; Majewski, S A; Miyashita, T S; Petersen, B A; Wilden, L; Ahmed, S; Alam, M S; Ernst, J A; Pan, B; Saeed, M A; Zain, S B; Spanier, S M; Wogsland, B J; Eckmann, R; Ritchie, J L; Ruland, A M; Schilling, C J; Schwitters, R F; Drummond, B W; Izen, J M; Lou, X C; Bianchi, F; Gamba, D; Pelliccioni, M; Bomben, M; Bosisio, L; Cartaro, C; Della Ricca, G; Lanceri, L; Vitale, L; Azzolini, V; Lopez-March, N; Martinez-Vidal, F; Milanes, D A; Oyanguren, A; Albert, J; Banerjee, Sw; Bhuyan, B; Choi, H H F; Hamano, K; Kowalewski, R; Lewczuk, M J; Nugent, I M; Roney, J M; Sobie, R J; Gershon, T J; Harrison, P F; Ilic, J; Latham, T E; Mohanty, G B; Band, H R; Chen, X; Dasu, S; Flood, K T; Pan, Y; Pierini, M; Prepost, R; Vuosalo, C O; Wu, S L

    2008-10-17

    With the full BABAR data sample of 465 x 10(6) B(over)B pairs, we observe the decays B+/- -->phiK_(1)(1270) +/- and B +/- -->phiK*_(2)(1430)+/-. We measure the branching fractions (6.1+/-1.6+/-1.1) x 10(-6) and (8.4+/-1.8+/-1.0) x 10(-6) and the fractions of longitudinal polarization 0.46 (+0.12+0.06) _(-0.13-0.07) and 0.80(+0.09)_(-0.10)+/-0.03, respectively. We also report on the B+/- -->phiK*_(0)(1430)+/- decay branching fraction of (7.0+/-1.3+/-0.9) x 10(-6) and several parameters sensitive to CP violation and interference in the above three decays. Upper limits are placed on the B+/- decay rates to final states with phi and K_1(1400)+/-, K*(1410)+/-, K2(1770)+/-, or K_2(1820)+/-. Understanding the observed polarization pattern requires amplitude contributions from an uncertain source.

  18. Ultra-Short-Period Planets in K2: New Results From SuPerPiG

    Science.gov (United States)

    Adams, Elisabeth; Jackson, Brian; Endl, Michael

    2016-10-01

    Ultra-short-period planets, with orbital periods of less than 1 day, are a challenge to theories of planet formation. The SuPerPiG collaboration (Short-Period Planet Group) reports on 19 candidates identified in Campaigns 0-5 of the K2 mission. Planet candidates range in size from 0.7-16 Earth radii and in orbital period from 4.2 to 23.5 hours. One candidate (EPIC 203533312, Kp=12.5) is among the shortest-period planet candidates discovered to date (P=4.2 hours), and, if confirmed as a planet, must have a density of at least rho=8.9 g/cm^3 in order to not be tidally disrupted. Five candidates have nominal radius values in the sub-Jovian desert (R_P=3-11 R_E and P<=1.5 days) where theoretical models do not favor their long-term stability; the only confirmed planet in this range is thought to be disintegrating (EPIC 201637175). Based on an assessment of our survey's completeness, we estimate an occurrence rate for ultra-short-period planets among K2 target stars that is about half that estimated from the Kepler sample, raising questions as to whether K2 systems are intrinsically different from Kepler systems, possibly as a result of their different galactic location.

  19. Rotation in the Pleiades with K2. III. Speculations on Origins and Evolution

    Science.gov (United States)

    Stauffer, John; Rebull, Luisa; Bouvier, Jerome; Hillenbrand, Lynne A.; Collier-Cameron, Andrew; Pinsonneault, Marc; Aigrain, Suzanne; Barrado, David; Bouy, Herve; Ciardi, David; Cody, Ann Marie; David, Trevor; Micela, Giusi; Soderblom, David; Somers, Garrett; Stassun, Keivan G.; Valenti, Jeff; Vrba, Frederick J.

    2016-11-01

    We use high-quality K2 light curves for hundreds of stars in the Pleiades to better understand the angular momentum evolution and magnetic dynamos of young low-mass stars. The K2 light curves provide not only rotational periods but also detailed information from the shape of the phased light curve that was not available in previous studies. A slowly rotating sequence begins at {(V-{K}{{s}})}0 ˜ 1.1 (spectral type F5) and ends at {(V-{K}{{s}})}0 ˜ 3.7 (spectral type K8), with periods rising from ˜2 to ˜11 days in that interval. A total of 52% of the Pleiades members in that color interval have periods within 30% of a curve defining the slow sequence; the slowly rotating fraction decreases significantly redward of {(V-{K}{{s}})}0 = 2.6. Nearly all of the slow-sequence stars show light curves that evolve significantly on timescales less than the K2 campaign duration. The majority of the FGK Pleiades members identified as photometric binaries are relatively rapidly rotating, perhaps because binarity inhibits star-disk angular momentum loss mechanisms during pre-main-sequence evolution. The fully convective late M dwarf Pleiades members (5.0 parent population of single stars.

  20. Tumor-specificity and type of cell death induced by vitamin K2 derivatives and prenylalcohols.

    Science.gov (United States)

    Sakagami, Hiroshi; Hashimoto, Ken; Suzuki, Fumika; Ishihara, Mariko; Kikuchi, Hirotaka; Katayama, Tadashi; Satoh, Kazue

    2008-01-01

    Fourteen vitamin K2 (menaquinone (MK)-n, n = 1-14) and ten prenylalcohol derivatives (n = 1-10) with different numbers (n) of isoprenyl groups in the side chains were investigated for their cytotoxicity against nine human tumor cell lines and three human normal oral cells. Among the vitamin K2 derivatives, MK-2 (n = 2) showed the greatest cytotoxicity, followed by MK-1 (n = 1) and MK-3 (n = 3). MK-1, MK-2 and MK-3 showed the highest tumor-specific index (TS= > 2.0, 2.0 and > 1.7, respectively). Among the prenylalcohols, geranylgeraniol (GG) (n = 4) showed the highest cytotoxicity, followed by farnesol (n = 3) and geranylfarnesol (GF) (n = 3). GG showed the highest tumor-specificity (TS = 1.8), followed by farnesol (TS = > 1.4), GF (TS= > GFF (n = 8) which had lower cytotoxicity, produced radicals, suggesting the lack of connection between cytotoxicity and radical production. The present study demonstrates that the presence of 1,4-naphtoquinone structure (including alpha,beta-unsaturated ketones) in vitamin K2 derivatives confers on them the ability to induce non-apoptotic cell death.

  1. Improvement of Vitamin K2 Production by Escherichia sp. with Nitrogen Ion Beam Implantation Induction

    Science.gov (United States)

    Liu, Yan; Wang, Li; Zheng, Zhiming; Wang, Peng; Zhao, Genhai; Liu, Hui; Gong, Guohong; Wu, Hefang; Liu, Hongxia; Tan, Mu; Li, Zhemin

    2015-02-01

    Low-energy ion implantation as a novel mutagen has been increasingly applied in the microbial mutagenesis for its higher mutation frequency and wider mutation spectra. In this work, N+ ion beam implantation was used to enhance Escherichia sp. in vitamin K2 yield. Optimization of process parameters under submerged fermentation was carried out to improve the vitamin K2 yield of mutant FM5-632. The results indicate that an excellent mutant FM5-632 with a yield of 123.2±1.6 μg/L, that is four times that of the original strain, was achieved by eight successive implantations under the conditions of 15 keV and 60×2.6×1013 ions/cm2. A further optimization increased the yield of the mutant by 39.7%, i.e. 172.1±1.2 μg/L which occurred in the mutant cultivated in the optimal fermentation culture medium composed of (per liter): 15.31 g glycerol, 10 g peptone, 2.89 g yeast extract, 5 g K2HPO4, 1 g NaCl, 0.5 g MgSO4·7H2O and 0.04 g cedar wood oil, incubated at 33 °C, pH 7.0 and 180 rpm for 120 h.

  2. Rotation in the Pleiades With K2: III. Speculations on Origins and Evolution

    CERN Document Server

    Stauffer, J R; Bouvier, J; Hillenbrand, L A; Cameron, A Collier; Pinsonneault, M; Aigrain, S; Barrado, D; Bouy, H; Ciardi, D; Cody, A M; David, T; Micela, G; Soderblom, D; Somers, G; Stassun, K; Valenti, J; Vrba, F

    2016-01-01

    We use high quality K2 light curves for hundreds of stars in the Pleiades to understand better the angular momentum evolution and magnetic dynamos of young, low mass stars. The K2 light curves provide not only rotational periods but also detailed information from the shape of the phased light curve not available in previous studies. A slowly rotating sequence begins at $(V-K_{\\rm s})_0\\sim$1.1 (spectral type F5) and ends at $(V-K_{\\rm s})_0\\sim$ 3.7 (spectral type K8), with periods rising from $\\sim$2 to $\\sim$11 days in that interval. Fifty-two percent of the Pleiades members in that color interval have periods within 30\\% of a curve defining the slow sequence; the slowly rotating fraction decreases significantly redward of $(V-K_{\\rm s})_0$=2.6. Nearly all of the slow-sequence stars show light curves that evolve significantly on timescales less than the K2 campaign duration. The majority of the FGK Pleiades members identified as photometric binaries are relatively rapidly rotating, perhaps because binarity ...

  3. Clinical performance of Rose K2 soft contact lens for keratoconus

    Directory of Open Access Journals (Sweden)

    Ihsan Yilmaz

    2017-08-01

    Full Text Available AIM: To evaluate the comfort and visual performance of Rose K2 soft contact lenses in patients with keratoconus.METHODS: Fifty eyes of 50 participants were included in this cross-sectional study. Each participant received a full ophthalmologic examination involving refraction, uncorrected visual acuity(UCVA, best spectacle corrected visual acuity(BCVA, slit-lamp biomicroscopy-fundoscopy, break-up time(BUT, corneal topography, and contrast sensitivity. After contact lens was fitted best contact lens corrected visual acuity(BCLCVA, contrast sensitivity, and comfort rating via visual analogue scales(VASwere performed.RESULTS: The mean age was 26.2±6.0(range: 16 to 39y. The mean logMAR UCVA, BCVA, and BCLCVA with Rose K2 soft(in orderwere 0.61±0.37(range: 0.15-1.3, 0.42±0.32(range: 0-1.3, and 0.18±0.20(range: 0-1.3. There were significant increases in visual acuities with contact lenses(P P CONCLUSION: Rose K2 soft contact lens can improve visual acuity, contrast sensitivity with comfort in patients with keratoconus.

  4. Neptune's Dynamic Atmosphere from Kepler K2 Observations: Implications for Brown Dwarf Light Curve Analyses

    CERN Document Server

    Simon, Amy A; Gaulme, Patrick; Hammel, Heidi B; Casewell, Sarah L; Fortney, Jonathan J; Gizis, John E; Lissauer, Jack J; Morales-Juberias, Raul; Orton, Glenn S; Wong, Michael H; Marley, Mark S

    2015-01-01

    Observations of Neptune with the Kepler Space Telescope yield a 49-day light curve with 98% coverage at a 1-minute cadence. A significant signature in the light curve comes from discrete cloud features. We compare results extracted from the light curve data with contemporaneous disk-resolved imaging of Neptune from the Keck 10-meter telescope at 1.65 microns and Hubble Space Telescope visible imaging acquired 9 months later. This direct comparison validates the feature latitudes assigned to the K2 light curve periods based on Neptune's zonal wind profile, and confirms observed cloud feature variability. Although Neptune's clouds vary in location and intensity on short and long time scales, a single large discrete storm seen in Keck imaging dominates the K2 and Hubble light curves; smaller or fainter clouds likely contribute to short-term brightness variability. The K2 Neptune light curve, in conjunction with our imaging data, provides context for the interpretation of current and future brown dwarf and extras...

  5. 197 Candidates and 104 Validated Planets in K2's First Five Fields

    CERN Document Server

    Crossfield, Ian J M; Petigura, Erik A; Sinukoff, Evan; Schlieder, Joshua E; Howard, Andrew W; Beichman, Charles A; Isaacson, Howard; Dressing, Courtney D; Christiansen, Jessie L; Fulton, Benjamin J; Lépine, Sébastien; Weiss, Lauren; Hirsch, Lea; Livingston, John; Baranec, Christoph; Law, Nicholas M; Riddle, Reed; Ziegler, Carl; Howell, Steve B; Horch, Elliott; Everett, Mark; Teske, Johanna; Martinez, Arturo O; Obermeier, Christian; Benneke, Björn; Scott, Nic; Deacon, Niall; Aller, Kimberly M; Hansen, Brad M S; Mancini, Luigi; Ciceri, Simona; Brahm, Rafael; Jordán, Andrés; Knutson, Heather A; Henning, Thomas; Bonnefoy, Michaël; Liu, Michael C; Crepp, Justin R; Lothringer, Joshua; Hinz, Phil; Bailey, Vanessa; Skemer, Andrew; Defrere, Denis

    2016-01-01

    We present 197 planet candidates discovered using data from the first year of the NASA K2 mission (Campaigns 0-4), along with the results of an intensive program of photometric analyses, stellar spectroscopy, high-resolution imaging, and statistical validation. We distill these candidates into sets of 104 validated planets (57 in multi-planet systems), 30 false positives, and 63 remaining candidates. Our validated systems span a range of properties, with median values of R_P = 2.3 R_E, P=8.6 d, Tef = 5300 K, and Kp=12.7 mag. Stellar spectroscopy provides precise stellar and planetary parameters for most of these systems. We show that K2 has increased by 30% the number of small planets known to orbit moderately bright stars (1-4 R_E, Kp=9-13 mag). Of particular interest are 37 planets smaller than 2 R_E, 15 orbiting stars brighter than Kp=11.5, five receiving Earth-like irradiation levels, and several multi-planet systems -- including four planets orbiting the M dwarf K2-72 near mean-motion resonances. By quan...

  6. K2 Discovers a Busy Bee: An Unusual Transiting Neptune Found in the Beehive Cluster

    CERN Document Server

    Obermeier, Christian; Schlieder, Joshua E; Crossfield, Ian J M; Petigura, Erik A; Howard, Andrew W; Sinukoff, Evan; Isaacson, Howard; Ciardi, David R; David, Trevor J; Hillenbrand, Lynne A; Beichmann, Charles A; Howell, Steve B; Horch, Elliot; Everett, Mark; Hirsch, Lea; Teske, Johanna; Christiansen, Jessie L; Lépine, Sébastien; Aller, Kimberly M; Liu, Michael C; Saglia, Roberto P; Livingston, John; Kluge, Matthias

    2016-01-01

    Open clusters have been the focus of several exoplanet surveys but only a few planets have so far been discovered. The \\emph{Kepler} spacecraft revealed an abundance of small planets around small, cool stars, therefore, such cluster members are prime targets for exoplanet transit searches. Kepler's new mission, K2, is targeting several open clusters and star-forming regions around the ecliptic to search for transiting planets around their low-mass constituents. Here, we report the discovery of the first transiting planet in the intermediate-age (800 Myr) Beehive cluster (Praesepe). K2-95 is a faint ($\\mathrm{Kp = 15.5\\,mag}$) $\\mathrm{M3.0\\pm0.5}$ dwarf from K2's Campaign 5 with an effective temperature of $\\mathrm{3471 \\pm 124\\,K}$, approximately solar metallicity and a radius of $\\mathrm{0.402 \\pm 0.050 \\,R_\\odot}$. We detected a transiting planet with a radius of $\\mathrm{3.47^{+0.78}_{-0.53} \\, R_\\oplus}$ and an orbital period of 10.134 days. We combined photometry, medium/high-resolution spectroscopy, ad...

  7. Stellar statistics along the ecliptic and the impact on the K2 mission concept

    CERN Document Server

    Prsa, A; Barclay, T

    2014-01-01

    K2 is the mission concept for a repurposed Kepler mission that uses two reaction wheels to maintain the satellite attitude and provide ~85 days of coverage for ten 105-deg^2 fields along the ecliptic in the first 2.5 years of operation. We examine stellar populations based on the improved Besancon model of the Galaxy, comment on the general properties for the entire ecliptic plane, and provide stellar occurrence rates in the first 6 tentative K2 campaigns grouped by spectral type and luminosity class. For each campaign we distinguish between main sequence stars and giants and provide their density profile as a function of galactic latitude. We introduce the crowding metric that serves for optimized target selection across the campaigns. For all main sequence stars we compute the expected planetary occurrence rates for three planet sizes: 2-4 REarth, 4-8 REarth, and 8-32 REarth with orbital periods up to 50 days. In conjunction with Gaia and the upcoming TESS and Plato missions, K2 will become a gold mine for ...

  8. Computation of K2 for the ring of integers of quadratic imaginary fields

    Institute of Scientific and Technical Information of China (English)

    CHEN; Sheng

    2001-01-01

    [1]Tate,J.,Appendix,Algebraic K-theory,Lecture Notes in Math.,342,Berlin-Heidelberg-New York:Springer-Verlag,1973,429-446.[2]Bass,H.,Tate,J.,The Milnor ring of a global field,in Lecture Notes in Math.,342,Berlin-Heidelberg-New York:Springer-Verlag,1973,349-428.[3]Skalba,M.,Generalization of Thus's theorem and computation of the group K2OF,J.of Number Theory,1997,46:303-322.[4]Qin Hourong,Computation of K2Z-6],J.of Pure Appl.Algebra,1994,96:133-146.[5]Qin Hourong,Computation of K2Z(1+-35)/(2),Chinese Ann.Math.(B),1996,17(1):63-72.[6]Browkin,J.,Gangl,H.,Tame and wild kernels of quadratic imaginary number fields,Math.of Computation,1999,68(225):291-305.

  9. The ionic interaction of Klebsiella pneumoniae K2 capsule and core lipopolysaccharide.

    Science.gov (United States)

    Fresno, Sandra; Jiménez, Natalia; Izquierdo, Luis; Merino, Susana; Corsaro, Maria Michela; De Castro, Cristina; Parrilli, Michelangelo; Naldi, Teresa; Regué, Miguel; Tomás, Juan M

    2006-06-01

    The complete structures of LPS core types 1 and 2 from Klebsiella pneumoniae have been described by other authors. They are characterized by a lack of phosphoryl residues, but they contain galacturonic acid (GalA) residues, which contribute to the necessary negative charges. The presence of a capsule was determined in core-LPS non-polar mutants from strains 52145 (O1 : K2), DL1 (O1 : K1) and C3 (O8 : K66). O-antigen ligase (waaL) mutants produced a capsule. Core mutants containing the GalA residues were capsulated, while those lacking the residues were non capsulated. Since the proteins involved in the transfer of GalA (WabG) and glucosamine residues (WabH) are known, the chemical basis of the capsular-K2-cell-surface association was studied. Phenol/water extracts from K. pneumoniae 52145DeltawabH waaL and 52145DeltawaaL mutants, but not those from from K. pneumoniae 52145DeltawabG waaL mutant, contained both LPS and capsular polysaccharide, even after hydrophobic chromatography. The two polysaccharides were dissociated by gel-filtration chromatography, eluting with detergent and metal-ion chelators. From these results, it is concluded that the K2 capsular polysaccharide is associated by an ionic interaction to the LPS through the negative charge provided by the carboxyl groups of the GalA residues.

  10. Novel dinuclear dimethylamido-3,5-dimethylpyrazolato and tetranuclear dimethylamido-3,5-dimethylpyrazolato-polyoxo zirconium(IV) complexes. Synthesis and structural characterisation.

    Science.gov (United States)

    Sanz, Martial; Mosquera, Marta E G; Cuenca, Tomás

    2009-04-14

    The dinuclear dimethylamido-tris(3,5-dimethylpyrazolato)-zirconium(IV) complex [Zr(3,5-Me2Pz)3(NMe2)]2 1 is prepared by treatment of [Zr(NMe2)4] with 3 equivalents of 3,5-dimethylpyrazole (3,5-Me2PzH) with elimination of dimethylamine. When [Zr(NMe2)4] reacted with 2 equivalents of 3,5-Me2PzH, the bis(dimethylamido)-bis(3,5-dimethylpyrazolato)zirconium(IV) compound [Zr(3,5-Me2Pz)2(NMe2)2]2 2 is obtained. Hydrolysis of [Zr(3,5-Me2Pz)3(NMe2)]2 in wet toluene affords the tetranuclear oxo compound [Zr4(eta2-3,5-Me2Pz)4(NMe2)2(mu3-O)2(mu2-3,5-Me2Pz)4(mu2-NMe2)2] . All synthesised compounds are characterised by NMR spectroscopic and analytical methods. Single crystal X-ray diffraction analysis has established the molecular structures of 1 and 4.

  11. Adenosine 3':5'-cyclic monophosphate in higher plants: Isolation and characterization of adenosine 3':5'-cyclic monophosphate from Kalanchoe and Agave.

    Science.gov (United States)

    Ashton, A R; Polya, G M

    1977-07-01

    1.3':5'-Cyclic AMP was extensively purified from Kalanchoe daigremontiana and Agave americana by neutral alumina and anion- and cation-exchange column chromatography. Inclusion of 3':5'-cyclic [8-3H]AMP from the point of tissue extraction permitted calculation of yields. The purification procedure removed contaminating material that was shown to interfere with the 3':5'-cyclic AMP estimation and characterization procedures. 2. The partially purified 3':5'-cyclic AMP was quantified by means of a radiochemical saturation assay using an ox heart 3':5'-cyclic AMP-binding protein and by an assay involving activation of a mammalian protein kinase. 3. The plant 3':5'-cyclic AMP co-migrated with 3':5'-cyclic [8-3H]AMP on cellulose chromatography, poly(ethyleneimine)-cellulose chromatography and silica-gel t.l.c. developed with several solvent systems. 4. The plant 3':5'-cyclic AMP was degraded by ox heart 3':5'-cyclic nucleotide phosphodiesterase at the same rates as authentic 3':5'-cyclic AMP. 1-Methyl-3-isobutylxanthine (1 mM), a specific inhibitor of the 3':5'-cyclic nucleotide phosphodieterase, completely inhibited such degradation. 5. The concentrations of 3':5'-cyclic AMP satisfying the above criteria in Kalanchoe and Agave were 2-6 and 1 pmol/g fresh wt. respectively. Possible bacterial contribution to these analyses was estimated to be less than 0.002pmol/g fresh wt. Evidence for the occurrence of 3':5'-cyclic AMP in plants is discussed.

  12. The K2 M67 Study: Revisiting old friends with K2 reveals oscillating red giants in the open cluster M67

    CERN Document Server

    Stello, D; Casagrande, L; Gilliland, R; Aguirre, V S; Sandquist, E; Leiner, E; Mathieu, R; Soderblom, D R

    2016-01-01

    Observations of stellar clusters have had a tremendous impact in forming our understanding of stellar evolution. The open cluster M67 has a particularly important role as a calibration benchmark for stellar evolution theory due to its near solar composition and age. As a result, it has been observed extensively, including attempts to detect solar-like oscillations in its main sequence and red giant stars. However, any asteroseismic inference has so far remained elusive due to the difficulty in measuring these extremely low amplitude oscillations. Here we report the first unambiguous detection of solar-like oscillations in the red giants of M67. We use data from the Kepler ecliptic mission, K2, to measure the global asteroseismic properties. We find a model-independent seismic-informed distance of 816+/-11pc, or (m-M)o=9.57+/-0.03mag, an average red-giant mass of 1.36+/-0.01Msun, in agreement with the dynamical mass from an eclipsing binary near the cluster turn-off, and ages of individual stars compatible wit...

  13. Microwave Induced Synthesis of 3-Aryl-6-( 6-/8-substituted 4-chloroquinoline-3-yl) - s - triazolo [ 3,4- b ] - 1,3,4- thiadiazoles

    Institute of Scientific and Technical Information of China (English)

    QIAO,Ren-Zhong(乔仁忠); HUI,Xin-Ping(惠新平); XU,Peng-Fei(许鹏飞); ZHANG,Zi-Yi(张自义); CHENG,Dong-Liang(程东亮)

    2001-01-01

    The condensation of 4-amino-3-aryl-5-mercapto-1, 2, 4-tria-zoles (1a-f) with 6-/8-substituted 1,4-dihydro-4-oxo-quino-line-3-carboxylic acids (2a-d) in the presence of phosphorus oxychloride on refluxing or under microwave irradiation gave twenty four novel 3-aryl-6-(6-/8-substituted 4-chloroquinoline-3-yl)-s-triazolo[3,4-b]-1,3,4-thiadiazoles (4a-x), Consid-erable increase in the reaction rate has been observed with improved yields under microwave irradiation. The structures of the compounds synthesized were determined by elemental analyses, IR, 1H NMR and MS spectra. Their spectral properties and the reaction mechanism were also discussed. The preliminary biological test showed that some of compounds had moderate antibacterial activities.

  14. 6-8-aastase andeka lapse kodune kasvukeskkond ja arenguvõimalused Eestis ja Soomes / Maie Vikat, Inkeri Ruokonen, Eva Noormaa

    Index Scriptorium Estoniae

    Vikat, Maie

    2002-01-01

    1999.-2001.a. läbi viidud Tallinna Pedagoogikaülikooli ja Helsingi Ülikooli vahelisest uurimisprojektist "Andekas laps ja tema arengut soodustavad faktorid Eestis ja Soomes". Projekti eesmärk oli identifitseerida 6-8-aastaste laste andekus ja selle arengut soodustavad teguridühises kultuuris, kuid erineva sotsiaalmajandusliku arengutasemega ühiskondades Eesti ja Soome laste võrdleva analüüsi kaudu

  15. The Effect of Menstrual Health Education Conducted with Peer Education Method to Adolescent Girls in 6-8 Classes on Information and Behaviors

    OpenAIRE

    Zehra Golbasi; Gulbahtiyar Doganer; Nuriye Erbas

    2012-01-01

    Aim: Research was conducted as a experimental study in order to determine the effect of menstrual health education conducted with peer education to adolescent girls in 6-8 classes on information and behaviors. Method: The study was made in Primary School of Regional Girl Boarding. Working group consisted of 202 students responded completely pre-test and post-test from 214 female students studying in this school in 2008-2009 academic year. Data were collected by Personal Information Form, Mens...

  16. Sharpening of the 6.8 nm peak in an Nd:YAG laser produced Gd plasma by using a pre-formed plasma

    Directory of Open Access Journals (Sweden)

    Yong Tian

    2016-03-01

    Full Text Available For effective use of a laser-produced-plasma (LPP light source, an LPP is desired to emit a narrow spectral peak because the reflection spectrum of multilayer mirrors for guiding emission from the source is very narrow. While a Gd plasma has been studied extensively as an extreme ultraviolet (EUV light source at around 6.8 nm, where La/B4C multilayer is reported to have a high reflectivity with a bandwidth of about 0.6 %, all previous works using an Nd:YAG laser reported very broad spectra. This paper reports the first narrowing of the 6.8 nm peak in the case of using an Nd:YAG laser to generate a Gd plasma by using a pre-pulse. The best peak narrowing is observed when a pre-formed plasma is heated by a 1064 nm main laser pulse with a duration of 10 ns at the irradiation density of 4x 1011 W/cm2 at a delay time of 50 ns after the pre-pulse irradiation. The observed spectral width of about 0.3 nm is about one fifth of the value for no pre-formed plasma. The peak wavelength of the 6.8 nm band shifted to a longer wavelength side and the peak was broadened both for lower and higher laser irradiation density. It is discussed that this robustness of the peak position of the 6.8 nm Gd peak against temperature change is suitable to achieve a narrow bandwidth from an LPP generated on solid. The observed spectra are compared with those previously reported in various conditions.

  17. Facial Selectivity in the Nucleophilic Additions of endo-Tricyclo[5.2.1.O2.6]deca-2(6),8-dien-3-one

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Nucleophilic additions to endo-tricyclo[5.2.1.02.6]deca-2(6),8-dien-3-one 4 are described.Experimental results show high preference for exo-facial attack to the enone moiety of tricyclodecadienone. Steric hindrance is the main kinetically controlling factor in the nucleophilic reaction. The shielding effect and the stabilizing effect of the norbornene double bond favor the exo-facial attack also.

  18. Clearance effect of sandblasting and hand scaling on subgingival plaque and their effect on interleukin 1/6/8/10 and MMP8/TIMP1 levels

    Institute of Scientific and Technical Information of China (English)

    Lei Li

    2016-01-01

    Objective:To study the clearance effect of sandblasting and hand scaling on subgingival plaque and their effect on interleukin 1/6/8/10 and MMP8/TIMP1 levels.Methods: A total of 40 patients with subgingival plaque were selected for study, subgingival plaque of left half mouth received hand scaling and was included in hand scaling group, subgingival plaque of right half mouth received sandblasting scaling and was included in sandblasting group, probing depth (PD) and bleeding on probing (BOP) were assessed and the percentage of closed periodontal pocket was calculate before and after treatment; gingival crevicular fluid was collected after treatment to determine interleukin 1/6/8/10 and MMP8/TIMP1 levels.Results:7 d and 30 d after treatment, PD and BOP percentage of both groups were lower than those before treatment and the percentage of closed periodontal pocket were higher than those before treatment, the PD and BOP percentage of sandblasting group after treatment were lower than those of hand scaling group and the percentage of closed periodontal pocket was higher than that of hand scaling group; 7 d after treatment, IL-1, -6, -8 and MMP8 levels and MMP8/TIMP1 ratio in gingival crevicular fluid of sandblasting group were significantly lower than those of hand scaling group while IL-10 and TIMP1 levels were significantly higher than those of hand scaling group.Conclusion:Sandblasting scaling has better clearance effect on subgingival plaque than hand scaling, and can adjust the interleukin 1/6/8/10 and MMP8/TIMP1 levels to relieve periodontal tissue inflammation and alveolar bone resorption.

  19. The nuclear structure and related properties of some low-lying isomers of free-space O_n clusters (n=6, 8, 12)

    CERN Document Server

    Forte, G; March, N H; Pucci, R

    2013-01-01

    After some introductory comments relating to antiferromagnetism of crystalline O_2, and brief remarks on the geometry of ozone, Hartree-Fock (HF) theory plus second-order Moller-Plesset (MP2) corrections are used to predict the nuclear structure of low-lying isomers of free-space O_n clusters, for n=6, 8, and 12. The equilibrium nuclear-nuclear potential energy is also discussed in relation to the number n of oxygen atoms in the cluster.

  20. K2O/SBA-15的制备及其催化性能研究%Preparation and catalytic performance of mesoporous sieve catalyst K2O/SBA-15

    Institute of Scientific and Technical Information of China (English)

    崔晓燕; 沈健

    2011-01-01

    When potassium which was loaded to mesoporous sieve SBA-15 was calcined, K2O/SBA-15 as the solid base catalyst was synthesized. The synthesis of N-butyl acrylate was the probe reaction. The active value of K2O/SBA-15 catalyst has been carried on the transesterification in the inter mittent reactor.The results showed K2O/SBA-15 catalyst had the best catalytic active when the loaded amount of K2O added to 2%%以介孔分子筛SBA-15为载体,负载KNO3后焙烧制得K2O/SBA-15固体碱催化剂,以合成丙烯酸正丁酯的酯交换反应为探针反应,在间歇式反应釜中对K2O/SBA-15催化剂进行催化活性评价.结果表明,当K2O负载量为2%,K2O/SBA-15催化剂对此酯交换反应的催化活性最高.

  1. Effect of three 2-allyl-p-mentha-6,8-dien-2-ols on inhibition of mild steel corrosion in 1 M HCl

    Directory of Open Access Journals (Sweden)

    S. Kharchouf

    2014-11-01

    Full Text Available 2-Allyl-p-mentha-6,8-dien-2-ols P1−P3 synthesized from carvone P are tested as corrosion inhibitors of steel in 1 M HCl using weight loss measurements, potentiodynamic polarisation and impedance spectroscopy (EIS methods. The addition of 2-allyl-p-mentha-6,8-dien-2-ols reduced the corrosion rate. Potentiodynamic polarisation studies clearly reveal that the presence of inhibitors does not change the mechanism of hydrogen evolution and that they act essentially as cathodic inhibitors. 2-Allyl-p-mentha-6,8-dien-2-ols tested adsorb on the steel surface according to Langmuir isotherm. From the adsorption isotherm some thermodynamic data for the adsorption process are calculated and discussed. EIS measurements show the increase of the charge-transfer resistance with the inhibitor concentration. The highest inhibition efficiency (92% is obtained for P1 at 3 g/L. The corrosion rate decreases with the rise of temperature. The corresponding activation energies are determined.

  2. 斯蒂芬酸钾的细化及性能%Refinement and Performance of K2TNR

    Institute of Scientific and Technical Information of China (English)

    张雪梅; 万贯; 张同来; 李志敏; 杨利; 张建国; 周遵宁

    2012-01-01

    The ultrafine K2TNR with particle size less than 10 μm was prepared by the method of microemulsion. In the process of synthesizing K2TNR, graphene nanopaper was added, and the sample G-K2TNR got. The electronic microscope and online size tester were used to characterize the morphology and size distribution. Thermal stability of three different K2TNR samples were analysed by differential scanning calorimetry(DSC) and dynamic vacuum stability test(DVST). Their 5s delay explosion temperatures were tested. The results show that the decomposition temperature of thinning K2TNR and G-K2TNR is advanced. The vacuum stability of thinning K2TNR is preferable. At the same time, the heat sensitivity of thinning K2TNR and G-K2TNR are improved obviously.%采用微乳液合成法制备出粒径在10μm以下的斯蒂芬酸钾(K2TNR).在合成K2TNR过程中,加入适量石墨烯纳米片得到掺杂后的K2TNR样品(G-K2TNR).用电子显微镜和在线粒度测试仪对样品形貌和粒度进行了分析.采用差示扫描量热分析仪(DSC)和动态真空安定性测试仪(DVST),测量了细化前后和掺杂石墨烯纳米片的3种K2TNR样品的热稳定性和5s爆发点.结果表明,细化后和掺杂后的K2TNR的热分解温度均有所提前,细化后样品真空安定性良好,热感度显著提高.

  3. The K2 M67 Study: Revisiting Old Friends with K2 Reveals Oscillating Red Giants in the Open Cluster M67

    Science.gov (United States)

    Stello, Dennis; Vanderburg, Andrew; Casagrande, Luca; Gilliland, Ron; Silva Aguirre, Victor; Sandquist, Eric; Leiner, Emily; Mathieu, Robert; Soderblom, David R.

    2016-12-01

    Observations of stellar clusters have had a tremendous impact in forming our understanding of stellar evolution. The open cluster M67 has a particularly important role as a calibration benchmark for stellar evolution theory due to its near-solar composition and age. As a result, it has been observed extensively, including attempts to detect solar-like oscillations in its main sequence and red giant stars. However, any asteroseismic inference has so far remained elusive due to the difficulty in measuring these extremely low-amplitude oscillations. Here we report the first unambiguous detection of solar-like oscillations in the red giants of M67. We use data from the Kepler ecliptic mission, K2, to measure the global asteroseismic properties. We find a model-independent seismic-informed distance of 816 ± 11 pc, or {(m-M)}0 = 9.57+/- 0.03 mag, an average red giant mass of 1.36+/- 0.01 {M}⊙ , in agreement with the dynamical mass from an eclipsing binary near the cluster turn-off, and ages of individual stars compatible with isochrone fitting. We see no evidence of strong mass loss on the red giant branch. We also determine seismic {log}g of all the cluster giants with a typical precision of ˜ 0.01 dex. Our results generally show good agreement with independent methods and support the use of seismic scaling relations to determine global properties of red giant stars with near-solar metallicity. We further illustrate that the data are of such high quality that future work on individual mode frequencies should be possible, which would extend the scope of seismic analysis of this cluster.

  4. 维生素K2防治骨质疏松症的研究进展%The research progress of vitamin K2 for the prevention and treatment of osteoporosis

    Institute of Scientific and Technical Information of China (English)

    胡江伟

    2011-01-01

    维生素K2是一种与骨形成和骨吸收有关的药物,具有促进骨形成和抑制骨吸收的双重作用.本文着重论述维生素K2对骨代谢的影响和维生素K2预防和治疗骨质疏松症的临床应用研究等方面的研究新进展.%Objective Vitamin K2 is a medicine related to bone formation and bone resorption. It has a dual function of stimulating bone formation and inhibiting bone resorption. This paper mainly reviews the research progress of the effect of vitamin K2 on bone metabolism and its clinical application for the prevention and treatment of osteoporosis.

  5. Enhancing Parent Involvement in NC-CCSS for K-2 Mathematics

    Science.gov (United States)

    Johnson, D.

    2014-12-01

    Key Terms:Parent Involvement, Common Core State Standards, Homework, K - 2 Mathematics In this study, the 2014 REU math team developed and provided a workshop that assisted parents in understanding the North Carolina Common Core State Standards for K-2 Mathematics to assist with student homework assignments. Parent involvement is defined as parent participating in the educational processes and experiences of their children. A chi-square analysis was used to analyze data collected from the pre survey and the post survey administered to participants in the workshop. The study revealed all of the individual components of parent involvement were positively and significantly related to educational goals. The study identified various aspects of parent involvement that yielded statistically significant results in affirming that parent involvement attributed to urban student achievement. These findings were particularly helpful for indicating which kinds of parent involvement influenced academic success. Most notably, parent expectations and styles demonstrated a strong relationship with scholastic outcomes. Parent expectations and styles created an educationally oriented ambience that established an understanding of the certain level of support the child needed to succeed academically. The REU mathematics team focused on three essential questions in this study: (1) What practices will increase parent awareness of K-2 NC-CCSS for mathematics at P. W. Moore Elementary School? (2) What methods can be used to strengthen parent skills in assisting with mathematics homework assignments at P. W. Moore Elementary School? (3) What actions can be taken to motivate parent involvement in the school improvement process focusing on mathematics at P. W. Moore Elementary School?

  6. Study of kinetic parameters of K 2Ca 2(SO 4)3 thermoluminescence dosimeter

    Science.gov (United States)

    Choubey, A.; Das, S.; Sharma, S. K.; Manam, J.

    The dosimetry study of thermoluminescence materials is based on a good knowledge of its kinetics para-meters. A polycrystalline sample of K 2Ca 2(SO 4)3 was prepared by the solid-state diffusion method. Formation of the compound was checked by using X-ray diffraction and Fourier-transform infrared spectroscopy. Thermally stimulated luminescence (TSL) glow curves of X-ray-irradiated K 2Ca 2(SO 4)3 phosphor exhibit one glow peak at 195 °C and a shoulder at around 120 °C, indicating that two different sets of traps are being activated within the particular temperature range, each with its own value of activation energy (E) and frequency factor (s). The kinetic parameters associated with the prominent glow peak of K 2Ca 2(SO 4)3 were calculated using the isothermal luminescence decay method. The electron spin resonance study of the prepared compound exhibits the presence of img style="vertical-align: text-bottom;" class="inlinematheqn" src="/ampp/image?path=/713648881/917117136/grad_a_438565_o_ilm0001.gif" alt="./GRAD_A_438565_O_XML_IMAGES/GRAD_A_438565_O_ILM0001.gif" border="0" /> and img style="vertical-align: text-bottom;" class="inlinematheqn" src="/ampp/image?path=/713648881/917117136/grad_a_438565_o_ilm0002.gif" alt="./GRAD_A_438565_O_XML_IMAGES/GRAD_A_438565_O_ILM0002.gif" border="0" /> radical ions that are responsible for the observed TSL glow peaks. The release of hole/electron from trap centres at the characteristic trap site initiates the luminescence process in these materials.

  7. The efficacy of vitamin K2 and calcitriol combination on thalassemic osteopathy.

    Science.gov (United States)

    Ozdemir, Mehmet A; Yilmaz, Kenan; Abdulrezzak, Ummuhan; Muhtaroglu, Sebahattin; Patiroglu, Turkan; Karakukcu, Musa; Unal, Ekrem

    2013-11-01

    Thalassemic osteopathy (TOSP) has emerged as a topic of interest, as the optimized transfusion regimens and iron chelations has markedly improved the survival of the patients suffering from thalassemia major (TM) and increased the life expectancy. The aim of this prospective monocentric pilot study was to investigate the effects of a dietary supplement with vitamin K2 (50 mcg menaquinone-7) and vitamin D (5 mcg calcitriol) on the patients with TOSP. Twenty children (12 girls, 8 boys; age varied from 3 to 18 y) with β TM, who underwent regular blood transfusion and iron chelation therapy, were enrolled in this study and investigated at the initial, sixth, and 12th month of the treatment. We detected a significant improvement in the bone mineral density and Z-score at the lumbar spine area of the patients at the sixth and 12th month of the treatment, especially in the prepubertal group. We also found a decrease in the ratio of undercarboxylated osteocalcin to carboxylated osteocalcin, however, this was not found to be significant. Although the natural course of TOSP is worsening or at least stabilizing, our pilot study demonstrated that vitamin K2 and calcitriol combination clearly has a positive effect on the bone mineral density of the children with TM during a 1-year period. Supplementation of menaquinone-7 instead of drugs is an augmented physiological intake and seems a beneficial alternative for the treatment of TOSP. Further studies on a large number of participants are necessary to highlight the effect of vitamin K2 on TOSP.

  8. Discovery and Validation of a High-Density sub-Neptune from the K2 Mission

    Science.gov (United States)

    Espinoza, Néstor; Brahm, Rafael; Jordán, Andrés; Jenkins, James S.; Rojas, Felipe; Jofré, Paula; Mädler, Thomas; Rabus, Markus; Chanamé, Julio; Pantoja, Blake; Soto, Maritza G.; Morzinski, Katie M.; Males, Jared R.; Ward-Duong, Kimberly; Close, Laird M.

    2016-10-01

    We report the discovery of K2-56b, a high-density sub-Neptune exoplanet, made using photometry from Campaign 4 of the two-wheeled Kepler (K2) mission, ground-based radial velocity (RV) follow-up from HARPS and high-resolution lucky and adaptive optics imaging obtained using AstraLux and MagAO, respectively. The host star is a bright (V = 11.04, K s = 9.37), slightly metal-poor ([Fe/H] = ‑0.15 ± 0.05 dex) solar analogue located at {152.1}-7.4+9.7 pc from Earth, for which we find a radius of {R}* ={0.928}-0.040+0.055{R}ȯ and a mass of {M}* ={0.961}-0.029+0.032{M}ȯ . A joint analysis of the K2 photometry and HARPS RVs reveal that the planet is in a ≈42 day orbit around its host star, has a radius of {2.23}-0.11+0.14{R}\\oplus , and a mass of {16.3}-6.1+6.0{M}\\oplus . Although the data at hand put the planet in the region of the mass–radius diagram where we could expect planets with a pure rock (i.e., magnesium silicate) composition using two-layer models (i.e., between rock/iron and rock/ice compositions), we discuss more realistic three-layer composition models which can explain the high density of the discovered exoplanet. The fact that the planet lies in the boundary between “possibly rocky” and “non-rocky” exoplanets makes it an interesting planet for future RV follow-up.

  9. Finding Planets in K2: A New Method of Cleaning the Data

    Science.gov (United States)

    Currie, Miles; Mullally, Fergal; Thompson, Susan E.

    2017-01-01

    We present a new method of removing systematic flux variations from K2 light curves by employing a pixel-level principal component analysis (PCA). This method decomposes the light curves into its principal components (eigenvectors), each with an associated eigenvalue, the value of which is correlated to how much influence the basis vector has on the shape of the light curve. This method assumes that the most influential basis vectors will correspond to the unwanted systematic variations in the light curve produced by K2’s constant motion. We correct the raw light curve by automatically fitting and removing the strongest principal components. The strongest principal components generally correspond to the flux variations that result from the motion of the star in the field of view. Our primary method of calculating the strongest principal components to correct for in the raw light curve estimates the noise by measuring the scatter in the light curve after using an algorithm for Savitsy-Golay detrending, which computes the combined photometric precision value (SG-CDPP value) used in classic Kepler. We calculate this value after correcting the raw light curve for each element in a list of cumulative sums of principal components so that we have as many noise estimate values as there are principal components. We then take the derivative of the list of SG-CDPP values and take the number of principal components that correlates to the point at which the derivative effectively goes to zero. This is the optimal number of principal components to exclude from the refitting of the light curve. We find that a pixel-level PCA is sufficient for cleaning unwanted systematic and natural noise from K2’s light curves. We present preliminary results and a basic comparison to other methods of reducing the noise from the flux variations.

  10. Correlation of CsK2Sb photocathode lifetime with antimony thickness

    Directory of Open Access Journals (Sweden)

    M. A. Mamun

    2015-06-01

    Full Text Available CsK2Sb photocathodes with quantum efficiency on the order of 10% at 532 nm, and lifetime greater than 90 days at low voltage, were successfully manufactured via co-deposition of alkali species emanating from an effusion source. Photocathodes were characterized as a function of antimony layer thickness and alkali consumption, inside a vacuum chamber that was initially baked, but frequently vented without re-baking. Photocathode lifetime measured at low voltage is correlated with the antimony layer thickness. Photocathodes manufactured with comparatively thick antimony layers exhibited the best lifetime. We speculate that the antimony layer serves as a reservoir, or sponge, for the alkali.

  11. VizieR Online Data Catalog: K2-19b light curve (Armstrong+, 2015)

    Science.gov (United States)

    Armstrong, D. J.; Santerne, A.; Veras, D.; Barros, S. C. C.; Demangeon, O.; Lillo-Box, J.; McCormac, J.; Osborn, H. P.; Tsantaki, M.; Almenara, J.-M.; Barrado, D.; Boisse, I.; Bonomo, A. S.; Brown, D. J. A.; Bruno, G.; Rey Cerda, J.; Courcol, B.; Deleuil, M.; Diaz, R. F.; Doyle, A. P.; Hebrard, G.; Kirk, J.; Lam, K. W. F.; Pollacco, D. L.; Rajpurohit, A.; Spake, J.; Walker, S. R.

    2015-08-01

    The Near Infrared Transiting ExoplanetS (NITES) Telescope is a semi-robotic 0.4m (f/10) Meade LX200GPS Schmidt-Cassegrain telescope installed at the ORM, La Palma. One transit of K2-19b was observed on 2015 Feb 28. The telescope was defocused slightly to 3.3 FWHM and 814 images of 20s exposure time were obtained with 5s dead time between each. Observations were obtained without a filter. The table presents data taken with the NITES telescope shown in Figure 1 of the publication. (1 data file).

  12. Chronic hypoxia, physical exercise and PSA: correlation during high-altitude trekking (2004 K2 expedition).

    Science.gov (United States)

    Verratti, Vittore; Di Giulio, Camillo; Di Francesco, Simona; Berardinelli, Francesco; Pellicciotta, Mario; Gidaro, Stefano; Zezza, Andrea; Tenaglia, Raffaele

    2007-01-01

    The aim of the present study was to identify the effects of physical exercise on PSA serum levels and the diagnostic validity of PSA in the screening of prostate cancer in subjects undergoing physical exercise during chronic hypoxia. The study was performed during trekking between 3,200 and 5,600 meters of altitude on K2 mountain for 26 days. Mean serum PSA values before and after exposure did not show significant difference due to physical exercise. These data indicate that physical exercise or mountain hypoxia do not affect the diagnostic validity of PSA.

  13. K2 C12 Raw Cadence TPFs for EVEREST TRAPPIST-1 De-trending

    OpenAIRE

    Luger, Rodrigo

    2017-01-01

    Raw data used by EVEREST to de-trend the TRAPPIST-1 K2 Campaign 12 raw cadence light curve. Check out the links below to read up on how to use this data. NOTE: The TRAPPIST-1 long cadence and short cadence TPFs have been updated to reflect the correct BJD times for every cadence. Previously, the timestamps were in geocentric time, yielding an offset of ~8 minutes, which primarily affected the precision of transit analyses in the short cadence data. HOWEVER, the timestamps in the auxiliary...

  14. Correlation of CsK2Sb photocathode lifetime with antimony thickness

    Energy Technology Data Exchange (ETDEWEB)

    Mamun, M. A. [Department of Mechanical and Aerospace Engineering, Old Dominion University, Norfolk, Virginia 23529, USA; The Applied Research Center, Thomas Jefferson National Accelerator Facility, Newport News, Virginia 23606, USA; Hernandez-Garcia, C. [Thomas Jefferson National Accelerator Facility, Newport News, Virginia 23606, USA; Poelker, M. [Thomas Jefferson National Accelerator Facility, Newport News, Virginia 23606, USA; Elmustafa, A. A. [Department of Mechanical and Aerospace Engineering, Old Dominion University, Norfolk, Virginia 23529, USA; The Applied Research Center, Thomas Jefferson National Accelerator Facility, Newport News, Virginia 23606, USA

    2015-06-01

    CsK2Sb photocathodes with quantum efficiency on the order of 10% at 532 nm, and lifetime greater than 90 days at low voltage, were successfully manufactured via co-deposition of alkali species emanating from an effusion source. Photocathodes were characterized as a function of antimony layer thickness and alkali consumption, inside a vacuum chamber that was initially baked, but frequently vented without re-baking. Photocathode lifetime measured at low voltage is correlated with the antimony layer thickness. Photocathodes manufactured with comparatively thick antimony layers exhibited the best lifetime. We speculate that the antimony layer serves as a reservoir, or sponge, for the alkali.

  15. Efficient 266 nm Ultraviolet Beam Generation in K2Al2B2O7 Crystal

    Institute of Scientific and Technical Information of China (English)

    吕军华; 王桂玲; 许祖彦; 陈创天; 王继扬; 张承乾; 刘耀岗

    2002-01-01

    The ultraviolet beam at 266 nm was obtained by fourth harmonic generation of 1064 nm Nd:YAG laser radiation through a nonlinear crystal K2Al2 B2O7 (KABO). The fundamental frequency of a Hash-lamp pumped Nd: YAG laser was doubled in a β-Ba2B2O4 crystal to generate a second harmonic output at the wavelength of 532 nm,and then doubled again in the KABO crystal to generate the fourth harmonic output at 266 nm. The optical conversion efficiency from 532 to 266 nm was investigated for the first time, and 13% was achieved.

  16. VizieR Online Data Catalog: K2 Ecliptic Plane Input Catalog (EPIC) (Huber+, 2017)

    Science.gov (United States)

    Huber, D.; Bryson, S. T.; et al.

    2017-09-01

    The construction of the EPIC, as well as modifications and shortcomings of the catalog are described in Huber+, 2016, J/ApJS/224/2 Changes for Campaigns 0-3, 7-10 and 16 are described in: http://archive.stsci.edu/k2/manuals/epic.pdf Kepler magnitudes (Kp) are shown to be accurate to ~0.1mag for the Kepler field, and the EPIC is typically complete to Kp~17 (Kp~19 for campaigns covered by Sloan Digital Sky Survey). (1 data file).

  17. Campaign 9 of the K2 mission

    DEFF Research Database (Denmark)

    Henderson, Calen B.; Poleski, Radosław; Penny, Matthew

    2016-01-01

    several that are planetary in nature as well as many short-timescale microlensing events, which are potentially indicative of free-floating planets (FFPs). These satellite parallax measurements will in turn allow for the direct measurement of the masses of and distances to the lensing systems...... of resources dedicated to concurrent observations. Finally, we outline the avenues through which the larger community can become involved, and generally encourage participation in K2C9, which constitutes an important pathfinding mission and community exercise in anticipation of WFIRST....

  18. Murine K2P5.1 Deficiency Has No Impact on Autoimmune Neuroinflammation due to Compensatory K2P3.1- and KV1.3-Dependent Mechanisms.

    Science.gov (United States)

    Bittner, Stefan; Bobak, Nicole; Hofmann, Majella-Sophie; Schuhmann, Michael K; Ruck, Tobias; Göbel, Kerstin; Brück, Wolfgang; Wiendl, Heinz; Meuth, Sven G

    2015-07-24

    Lymphocytes express potassium channels that regulate physiological cell functions, such as activation, proliferation and migration. Expression levels of K2P5.1 (TASK2; KCNK5) channels belonging to the family of two-pore domain potassium channels have previously been correlated to the activity of autoreactive T lymphocytes in patients with multiple sclerosis and rheumatoid arthritis. In humans, K2P5.1 channels are upregulated upon T cell stimulation and influence T cell effector functions. However, a further clinical translation of targeting K2P5.1 is currently hampered by a lack of highly selective inhibitors, making it necessary to evaluate the impact of KCNK5 in established preclinical animal disease models. We here demonstrate that K2P5.1 knockout (K2P5.1-/-) mice display no significant alterations concerning T cell cytokine production, proliferation rates, surface marker molecules or signaling pathways. In an experimental model of autoimmune neuroinflammation, K2P5.1-/- mice show a comparable disease course to wild-type animals and no major changes in the peripheral immune system or CNS compartment. A compensatory upregulation of the potassium channels K2P3.1 and KV1.3 seems to counterbalance the deletion of K2P5.1. As an alternative model mimicking autoimmune neuroinflammation, experimental autoimmune encephalomyelitis in the common marmoset has been proposed, especially for testing the efficacy of new potential drugs. Initial experiments show that K2P5.1 is functionally expressed on marmoset T lymphocytes, opening up the possibility for assessing future K2P5.1-targeting drugs.

  19. Murine K2P5.1 Deficiency Has No Impact on Autoimmune Neuroinflammation due to Compensatory K2P3.1- and KV1.3-Dependent Mechanisms

    Directory of Open Access Journals (Sweden)

    Stefan Bittner

    2015-07-01

    Full Text Available Lymphocytes express potassium channels that regulate physiological cell functions, such as activation, proliferation and migration. Expression levels of K2P5.1 (TASK2; KCNK5 channels belonging to the family of two-pore domain potassium channels have previously been correlated to the activity of autoreactive T lymphocytes in patients with multiple sclerosis and rheumatoid arthritis. In humans, K2P5.1 channels are upregulated upon T cell stimulation and influence T cell effector functions. However, a further clinical translation of targeting K2P5.1 is currently hampered by a lack of highly selective inhibitors, making it necessary to evaluate the impact of KCNK5 in established preclinical animal disease models. We here demonstrate that K2P5.1 knockout (K2P5.1−/− mice display no significant alterations concerning T cell cytokine production, proliferation rates, surface marker molecules or signaling pathways. In an experimental model of autoimmune neuroinflammation, K2P5.1−/− mice show a comparable disease course to wild-type animals and no major changes in the peripheral immune system or CNS compartment. A compensatory upregulation of the potassium channels K2P3.1 and KV1.3 seems to counterbalance the deletion of K2P5.1. As an alternative model mimicking autoimmune neuroinflammation, experimental autoimmune encephalomyelitis in the common marmoset has been proposed, especially for testing the efficacy of new potential drugs. Initial experiments show that K2P5.1 is functionally expressed on marmoset T lymphocytes, opening up the possibility for assessing future K2P5.1-targeting drugs.

  20. On two-primary algebraic K-theory of quadratic number rings with focus on K_2

    NARCIS (Netherlands)

    Crainic, M.; Østvær, Paul Arne

    2001-01-01

    We give explicit formulas for the 2-rank of the algebraic K-groups of quadratic number rings. A 4-rank formula for K2 of quadratic number rings given in [1] provides further information about the actual group structure. The K2 claculations are based on 2- and 4-rank formulas for Picard groups of qua

  1. Alterations of N-3 polyunsaturated fatty acid-activated K2P channels in hypoxia-induced pulmonary hypertension

    DEFF Research Database (Denmark)

    Nielsen, Gorm; Wandall-Frostholm, Christine; Sadda, Veeranjaneyulu

    2013-01-01

    relaxations that were resistant to endothelial removal and inhibition of NO and prostacyclin synthesis and to a cocktail of blockers of calcium-activated K(+) channels but were abolished by high extracellular (30 mM) K(+) -concentration. Gene expression and protein of K2P 2.1 were not altered in chronic...... hypoxic mice, while K2P 6.1 was up-regulated by fourfold. In conclusion, the PUFA-activated K2P 2.1 and K2P 6.1 are expressed in murine lung and functional K2P -like channels contribute to endothelium hyperpolarization and pulmonary artery relaxation. The increased K2P 6.1-gene expression may represent......Polyunsaturated fatty acid (PUFA)-activated two-pore domain potassium channels (K2P ) have been proposed to be expressed in the pulmonary vasculature. However, their physiological or pathophysiological roles are poorly defined. Here, we tested the hypothesis that PUFA-activated K2P are involved...

  2. Acute Oral Toxicity of 1-Acetyloctahydro-3,5,7-Trinitro-1,3,5,7-Tetrazocine (Sex) in Male and Female Rats.

    Science.gov (United States)

    1984-05-01

    flame proof cabinet at room temperature. %.. White--2 Chemical name: 1-Acetyloctahydro-3,5,7-Trinitro-1,3,5,7-Tetrazocine Chemical Abstract Service...Trinitrocyclotetramethylenetetramine Chemical Abstract Service Registry No.: 13980-00-2 Structural formula: 0 11 C-CH 0 2 N-N CH2 HC-N NO 2 , Empirical formula: C6H1

  3. The Study of Dissolution Kinetics of K2SO4 Crystal in Aqueous Ethanol Solutions with a Statistical Rate Theory

    Institute of Scientific and Technical Information of China (English)

    刘畅; 冯新; 吉晓燕; 陈栋梁; 魏涛; 陆小华

    2004-01-01

    Dissolution kinetics of K2SO4 crystal in aqueous ethanol solutions was studied on-line with ion selective electrode. The concentration of K2SO4 was calculated from the determined electromotive force in which the activity coefficient of components in the liquid phase was calculated with the Pitzer equation. Dissolution kinetic parameters in the modified statistical rate theory were regressed. The correlation results show that dissolution rate of K2SO4 is slower in aqueous ethanol solutions than that in aqueous solutions. The two most important reasons are as follows: (1) The solubility of K2SO4 in aqueous ethanol solutions is lower than that in aqueous solutions, which causes a decrease of the driving force of mass transfer. (2) The process of surface reaction of K2SO4 became slower due to the addition of ethanol, so that the whole process is mainly dominated by the surface reaction instead of mass transfer.

  4. The PanK2 Genes of Mouse and Human Specify Proteins with DistinctSubcellular Locations

    Energy Technology Data Exchange (ETDEWEB)

    Leonardi, Roberta; Zhang, Yong-Mei; Lydikis, Athanasios; Stevens,Robert D.; Ilkayeva, Olga R.; Wenner, Brett R.; Bain, James R.; Newgard,Christopher B.; Rock, Charles O.; Jackowski, Suzanne

    2007-05-01

    Coenzyme A (CoA) biosynthesis is initiated by pantothenatekinase (PanK) and CoA levels are controlled through differentialexpression and feedback regulation of PanK isoforms. PanK2 is amitochondrial protein in humans, but comparative genomics revealed thatacquisition of a mitochondrial targeting signal was limited to primates.Human and mouse PanK2 possessed similar biochemical properties, withinhibition by acetylCoA and activation by palmitoylcarnitine. Mouse PanK2localized in the cytosol, and the expression of PanK2 was higher in humanbrain compared to mouse brain. Differences in expression and subcellularlocalization should be considered in developing a mouse model for humanPanK2 deficiency. (c) 2007 Federation of European Biochemical Societies.Published by Elsevier B.V.

  5. Simulation and modeling CO2 absorption in biogas with DEA promoted K2CO3 solution in packed column

    Science.gov (United States)

    Nurkhamidah, Siti; Altway, Ali; Airlangga, Bramantyo; Emilia, Dwi Putri

    2017-05-01

    Absorption of carbon dioxide (CO2) using potassium carbonate (K2CO3) is one of biogas purification method. However, K2CO3 have slow mass transfer in liquid phase. So it is necessary to eliminate the disadvantage of CO2 absorption using K2CO3 by adding promotor (activator). Diethanol amine (DEA) is one of promotor which can increase its reaction rate. Simulation and modeling research of the CO2 absorption from biogas with DEA promoted K2CO3 solution has not been conducted. Thus, the main goal of this research is create model and simulation for the CO2 absorption from biogas with DEA promoted K2CO3 solution, then observe the influence of promoter concentration. DEA concentration varies between 1-5 %wt. From the simulation, we concluded that the CO2 removal rise with the increasing of promoter concentration. The highest CO2 removal is 54.5318 % at 5 % wt DEA concentration.

  6. A nearby M star with three transiting super-Earths discovered by K2

    CERN Document Server

    Crossfield, Ian J M; Schlieder, Joshua; Howard, Andrew W; Fulton, B J; Aller, Kimberly M; Ciardi, David R; Lepine, Sebastien; Barclay, Thomas; de Pater, Imke; de Kleer, Katherine; Quintana, Elisa V; Christiansen, Jessie L; Schlafly, Eddie; Kaltenegger, Lisa; Crepp, Justin R; Henning, Thomas; Obermeier, Christian; Deacon, Niall; Hansen, Brad M S; Liu, Michael C; Greene, Tom; Howell, Steve B; Barman, Travis; Mordasini, Christoph

    2015-01-01

    Small, cool planets represent the typical end-products of planetary formation. Studying the archi- tectures of these systems, measuring planet masses and radii, and observing these planets' atmospheres during transit directly informs theories of planet assembly, migration, and evolution. Here we report the discovery of three small planets orbiting a bright (Ks = 8.6 mag) M0 dwarf using data collected as part of K2, the new transit survey using the re-purposed Kepler spacecraft. Stellar spectroscopy and K2 photometry indicate that the system hosts three transiting planets with radii 1.5-2.1 R_Earth, straddling the transition region between rocky and increasingly volatile-dominated compositions. With orbital periods of 10-45 days the planets receive just 1.5-10x the flux incident on Earth, making these some of the coolest small planets known orbiting a nearby star; planet d is located near the inner edge of the system's habitable zone. The bright, low-mass star makes this system an excellent laboratory to deter...

  7. Adsorption of reactive brilliant red K-2BP on activated carbon developed from sewage sludge

    Institute of Scientific and Technical Information of China (English)

    Jiankun XIE; Qinyan YUE; Hui YU; Wenwen YUE; Renbo LI; Shengxiao ZHANG; Xiaona WANG

    2008-01-01

    Activated carbon was prepared from the sewage sludge of municipal wastewater treatment plant by chemical activation (activation reagent is ZnCl2) and was used for the adsorption of dye (reactive brilliant red K-2BP). The impact of adsorbent amount, adsorption time and pH value on adsorption effect, the adsorption kinetics, and the adsorption thermodynamics were dis-cussed according to batch adsorption tests. The results indicated that the activated carbon developed from sewage sludge (ACSS), which was mesoporous, possessed opened porous structures. The iodine number of the ACSS was heavy metals in the leachate didn't exceed the contents limit. The adsorption kinetics of reactive brilliant red K-2BP on the ACSS was accorded with the two-step kinetics rate equation and pseudo-second-order kinetics equation. Compared to the Freundlich isotherm equation, the Langmuir isotherm equation showed better applicability for the adsorption. The adsorption which was favorable was an endothermic (enthalpy △H > 0) and spontaneous (flee energy △G 0).

  8. Rotation in the Pleiades with K2: II. Multi-Period Stars

    CERN Document Server

    Rebull, L M; Bouvier, J; Cody, A M; Hillenbrand, L A; Soderblom, D R; Valenti, J; Barrado, D; Bouy, H; Ciardi, D; Pinsonneault, M; Stassun, K; Micela, G; Aigrain, S; Vrba, F; Somers, G; Gillen, E; Cameron, A Collier

    2016-01-01

    We use K2 to continue the exploration of the distribution of rotation periods in Pleiades that we began in Paper I. We have discovered complicated multi-period behavior in Pleiades stars using these K2 data, and we have grouped them into categories, which are the focal part of this paper. About 24% of the sample has multiple, real frequencies in the periodogram, sometimes manifesting as obvious beating in the light curves. Those having complex and/or structured periodogram peaks, unresolved multiple periods, and resolved close multiple periods are likely due to spot/spot group evolution and/or latitudinal differential rotation; these largely compose the slowly rotating sequence in $P$ vs.~$(V-K_{\\rm s})_0$ identified in Paper I. The fast sequence in $P$ vs.~$(V-K_{\\rm s})_0$ is dominated by single-period stars; these are likely to be rotating as solid bodies. Paper III continues the discussion, speculating about the origin and evolution of the period distribution in the Pleiades.

  9. WASP-47: A Hot Jupiter System with Two Additional Planets Discovered by K2

    CERN Document Server

    Becker, Juliette C; Adams, Fred C; Rappaport, Saul A; Schwengeler, Hans Martin

    2015-01-01

    Using new data from the K2 mission, we show that WASP-47, a previously known hot Jupiter host, also hosts two additional transiting planets: a Neptune-sized outer planet and a super-Earth inner companion. We measure planetary properties from the K2 light curve and detect transit timing variations, confirming the planetary nature of the outer planet. We performed a large number of numerical simulations to study the dynamical stability of the system and to find the theoretically expected transit timing variations (TTVs). The theoretically predicted TTVs are in good agreement with those observed, and we use the TTVs to determine the masses of two planets, and place a limit on the third. The WASP-47 planetary system is important because companion planets can both be inferred by TTVs and are also detected directly through transit observations. The depth of the hot Jupiter's transits make ground-based TTV measurements possible, and the brightness of the host star makes it amenable for precise radial velocity measur...

  10. Biodiesel preparation from Jatropha curcas oil catalyzed by hydrotalcite loaded with K2CO3.

    Science.gov (United States)

    Teng, Guangyuan; Gao, Lijing; Xiao, Guomin; Liu, Hu; Lv, Jianhua

    2010-11-01

    This paper discusses the synthesis of biodiesel catalyzed by solid base of K(2)CO(3)/HT using Jatropha curcas oil as feedstock. Mg-Al hydrotalcite was prepared using co-precipitation methods, in which the molar ratio of Mg to Al was 3:1. After calcined at 600 degrees C for 3 h, the Mg-Al hydrotalcite and K(2)CO(3) were ground and mixed according to certain mass ratios, in which some water was added. The mixture was dried at 65 degrees C, and after that it was calcined at 600 degrees C for 3 h. Then, this Mg-Al hydrotalcite loaded with potassium carbonate was obtained and used as catalyst in the experiments. Analyses of XRD and SEM characterizations for catalyst showed the metal oxides formed in the process of calcination brought about excellent catalysis effect. In order to achieve the optimal technical reaction condition, five impact factors were also investigated in the experiments, which were mass ratio, molar ratio, reaction temperature, catalyst amount and reaction time. Under the best condition, the biodiesel yield could reach up to 96%.

  11. Phase diagram and quantum order by disorder in the Kitaev K1-K2 honeycomb magnet

    Science.gov (United States)

    Rousochatzakis, Ioannis; Reuther, Johannes; Thomale, Ronny; Rachel, Stephan; Perkins, Natalia

    We show that the topological Kitaev spin liquid on the honeycomb lattice is extremely fragile against the second neighbor Kitaev coupling K2, which has been recently identified as the dominant perturbation away from the nearest neighbor model in iridate Na2IrO3, and may also play a role in α-RuCl3. This coupling explains naturally the zig-zag ordering and the special entanglement between real and spin space observed recently in Na2IrO3. The minimal K1-K2 model that we present here holds in addition the unique property that the classical and quantum phase diagrams and their respective order-by-disorder mechanisms are qualitatively different due to their fundamentally different symmetry structure. Nsf DMR-1511768; Freie Univ. Berlin Excellence Initiative of German Research Foundation; European Research Council, ERC-StG-336012; DFG-SFB 1170; DFG-SFB 1143, DFG-SPP 1666, and Helmholtz association VI-521.

  12. SDSS J1152+0248: An eclipsing double white dwarf from the Kepler K2 campaign

    CERN Document Server

    Hallakoun, N; Kilic, M; Mazeh, T; Agol, E; Bell, K J; Bloemen, S; Brown, W R; Debes, J; Faigler, S; Gianninas, A; Kull, I; Kupfer, T; Loeb, A; Morris, B M; Mullally, F

    2015-01-01

    We report the discovery of the sixth known eclipsing double white dwarf (WD) system, SDSS J1152+0248, with a 2.39677 +/- 0.00001 h orbital period, in data from the Kepler Mission's K2 continuation. Analysing and modelling the K2 data together with ground-based fast photometry, spectroscopy, and radial-velocity measurements, we determine that the primary is a DA-type WD with mass M1 = 0.378 +/- 0.047 Msun, radius R1 = 0.0209 +/- 0.0021 Rsun, and cooling age t1 = 65 +/- 34 Myr. No lines are detected, to within our sensitivity, from the secondary WD, but it is likely also of type DA. Its central surface flux, as measured from the secondary eclipse, is 0.31 of the primary flux. Its mass, radius, and cooling age, respectively, are M2 = 0.226 +0.073 -0.052 Msun, R2 = 0.0235 +0.0055 -0.0044 Rsun, and 220 +/- 100 Myr. SDSS J1152+0248 is almost a twin of the double-lined eclipsing WD system CSS 41177.

  13. TASK-2: a K2P K+ channel with complex regulation and diverse physiological functions

    Directory of Open Access Journals (Sweden)

    Luis Pablo Cid

    2013-07-01

    Full Text Available TASK-2 (K2P5.1 is a two-pore domain K+ channel belonging to the TALK subgroup of the K2P family of proteins. TASK-2 has been shown to be activated by extra- and intracellular alkalinisation. Extra- and intracellular pH-sensors reside at arginine 224 and lysine 245 and might affect separate selectivity filter and inner gates respectively. TASK-2 is modulated by changes in cell volume and a regulation by direct G-protein interaction has also been proposed. Activation by extracellular alkalinisation has been associated with a role of TASK-2 in kidney proximal tubule bicarbonate reabsorption, whilst intracellular pH-sensitivity might be the mechanism for its participation in central chemosensitive neurons. In addition to these functions TASK-2 has been proposed to play a part in apoptotic volume decrease in kidney cells and in volume regulation of glial cells and T-lymphocytes. TASK-2 is present in chondrocytes of hyaline cartilage, where it is proposed to play a central role in stabilizing the membrane potential. Additional sites of expression are dorsal root ganglion neurons, endocrine and exocrine pancreas and intestinal smooth muscle cells. TASK-2 has been associated with the regulation of proliferation of breast cancer cells and could become target for breast cancer therapeutics. Further work in native tissues and cells together with genetic modification will no doubt reveal the details of TASK-2 functions that we are only starting to suspect.

  14. K2 Rotation Periods for low-mass Hyads and the Implications for Gyrochronology

    CERN Document Server

    Douglas, S T; Covey, K R; Cargile, P A; Barclay, T; Cody, A; Howell, S B; Kopytova, T

    2016-01-01

    As the closest open cluster to the Sun, the Hyades is an important benchmark for many stellar properties, but its members are also scattered widely over the sky. Previous studies of stellar rotation in the Hyades relied on targeted observations of single stars or data from shallower all-sky variability surveys. The re-purposed Kepler mission, K2, is the first opportunity to measure rotation periods ($P_{rot}$) for many Hyads simultaneously while also being sensitive to fully convective M dwarf members. We analyze K2 data for 65 Hyads and present $P_{rot}$ values for 48. Thirty-seven of these are new measurements, including the first $P_{rot}$ measurements for fully convective Hyads. For nine of the 11 stars with $P_{rot}$ in the literature and this work, the measurements are consistent; we attribute the two discrepant cases to spot evolution. Nearly all stars with masses $\\le0.3M_\\odot$ are rapidly rotating, indicating a change in rotation properties at the boundary to full convection. When confirmed and cand...

  15. The Mass-Radius Relation of Young Stars from K2

    Science.gov (United States)

    Kraus, Adam L.; Cody, Ann Marie; Covey, Kevin R.; Rizzuto, Aaron C.; Mann, Andrew; Ireland, Michael; Jensen, Eric L. N.; Muirhead, Philip Steven

    2016-01-01

    Evolutionary models of pre-main sequence stars remain largely uncalibrated, especially for masses below that of the Sun, and dynamical masses and radii pose valuable tests of these theoretical models. Stellar mass dependent features of star formation (such as disk evolution, planet formation, and even the IMF) are fundamentally tied to these models, which implies a systematic uncertainty that can only be improved with precise measurements of calibrator stars. We will describe the discovery and characterization of ten eclipsing binary systems in the Upper Scorpius star-forming region from K2 Campaign 2 data, spanning from B stars to the substellar boundary. We have obtained complementary RV curves, spectral classifications, and high-resolution imaging for these targets; the combination of these data yield high-precision masses and radii for the binary components, and hence a dense sampling of the (nominally coeval) mass-radius relation of 10 Myr old stars. We already reported initial results from this program for the young M4.5 eclipsing binary UScoCTIO 5 (Kraus et al. 2015), demonstrating that theoretically predicted masses are discrepant by ~50% for low-mass stars. K2's unique radius measurements allow us to isolate the source of the discrepancy: models of young stars do not predict luminosities that are too low, as is commonly thought, but rather temperatures that are too warm.

  16. The K2-ESPRINT Project V: a short-period giant planet orbiting a subgiant star

    CERN Document Server

    Van Eylen, Vincent; Gandolfi, Davide; Dai, Fei; Winn, Joshua N; Hirano, Teriyuki; Narita, Norio; Bruntt, Hans; Prieto-Arranz, Jorge; Bejar, Victor J S; Nowak, Grzegorz; Lund, Mikkel N; Palle, Enric; Ribas, Ignasi; Sanchis-Ojeda, Roberto; Yu, Liang; Arriagada, Pamela; Butler, R Paul; Crane, Jeffrey D; Handberg, Rasmus; Deeg, Hans; Jessen-Hansen, Jens; Johnson, John A; Nespral, David; Rogers, Leslie; Ryu, Tsuguru; Shectman, Stephen; Shrotriya, Tushar; Slumstrup, Ditte; Takeda, Yoichi; Teske, Johanna; Thompson, Ian; Vanderburg, Andrew; Wittenmyer, Robert

    2016-01-01

    We report on the discovery and characterization of the transiting planet K2-39b (EPIC 206247743b). With an orbital period of 4.6 days, it is the shortest-period planet orbiting a subgiant star known to date. Such planets are rare, with only a handful of known cases. The reason for this is poorly understood, but may reflect differences in planet occurrence around the relatively high-mass stars that have been surveyed, or may be the result of tidal destruction of such planets. K2-39 is an evolved star with a spectroscopically derived stellar radius and mass of $3.88^{+0.48}_{-0.42}~\\mathrm{R_\\odot}$ and $1.53^{+0.13}_{-0.12}~\\mathrm{M_\\odot}$, respectively, and a very close-in transiting planet, with $a/R_\\star = 3.4$. Radial velocity (RV) follow-up using the HARPS, FIES and PFS instruments leads to a planetary mass of $50.3^{+9.7}_{-9.4}~\\mathrm{M_\\oplus}$. In combination with a radius measurement of $8.3 \\pm 1.1~\\mathrm{R_\\oplus}$, this results in a mean planetary density of $0.50^{+0.29}_{-0.17}$ g~cm$^{-3}$...

  17. Biodiesel synthesis using K2CO3/Al–O–Si aerogel catalysts

    Directory of Open Access Journals (Sweden)

    IVANA LUKIĆ

    2010-06-01

    Full Text Available In this study, catalysts for fatty acid methyl esters (FAME or bio-diesel synthesis with K2CO3 as the active component on an alumina/silica support were synthesized using the sol–gel method, which was followed by drying the “dense” wet gels with supercritical carbon dioxide to obtain the aerogels. The prepared catalysts were characterized by XRD analysis, FTIR spectroscopy and N2 physisorption at 77 K, and tested in the methanolysis of sunflower oil. The effects of reaction variables, such as reaction time, temperature and methanol to oil molar ratio, on the yield of FAME were investigated. The aerogel catalysts with K2CO3 as the active component on an alumina/silica support exhibited good activity in the methanolysis of sunflower oil. The leaching of potassium when the catalyst was in contact with pure methanol under the working conditions of methanolysis was also tested in this study, indicating that it occurred only at higher temperatures, while at lower ones, it was negligible.

  18. An RR Lyrae family portrait: 33 stars observed in Pisces with K2-E2

    CERN Document Server

    Molnár, L; Moskalik, P A; Nemec, J M; Guggenberger, E; Smolec, R; Poleski, R; Plachy, E; Kolenberg, K; Kolláth, Z

    2015-01-01

    A detailed analysis is presented of 33 RR Lyrae stars in Pisces observed with the Kepler space telescope over the 8.9-day long K2 Two-Wheel Concept Engineering Test. The sample includes not only fundamental-mode and first overtone (RRab and RRc) stars but the first two double-mode (RRd) stars that Kepler detected and the only modulated first-overtone star ever observed from space so far. The precision of the extracted K2 light curves made it possible to detect low-amplitude additional modes in all subtypes. All RRd and non-modulated RRc stars show the additional mode at P_X/P_1~0.61 that was detected in previous space-based photometric measurements. A periodicity longer than the fundamental mode was tentatively identified in one RRab star that might belong to a gravity mode. We determined the photometric [Fe/H] values for all fundamental-mode stars and provide the preliminary results of our efforts to fit the double-mode stars with non-linear hydrodynamic pulsation models. The results from this short test run...

  19. The K2-ESPRINT Project V: a short-period giant planet orbiting a subgiant star

    DEFF Research Database (Denmark)

    Van Eylen, Vincent; Albrecht, Simon; Gandolfi, Davide;

    2016-01-01

    {R_\\odot}$ and $1.53^{+0.13}_{-0.12}~\\mathrm{M_\\odot}$, respectively, and a very close-in transiting planet, with $a/R_\\star = 3.4$. Radial velocity (RV) follow-up using the HARPS, FIES and PFS instruments leads to a planetary mass of $50.3^{+9.7}_{-9.4}~\\mathrm{M_\\oplus}$. In combination with a radius measurement......We report on the discovery and characterization of the transiting planet K2-39b (EPIC 206247743b). With an orbital period of 4.6 days, it is the shortest-period planet orbiting a subgiant star known to date. Such planets are rare, with only a handful of known cases. The reason for this is poorly...... understood, but may reflect differences in planet occurrence around the relatively high-mass stars that have been surveyed, or may be the result of tidal destruction of such planets. K2-39 is an evolved star with a spectroscopically derived stellar radius and mass of $3.88^{+0.48}_{-0.42}~\\mathrm...

  20. 1,3,5-Triethylbenzene Transformation Reactions Compared to Its Transalkylation Reaction with Ethylbenzene

    KAUST Repository

    Akhtar, M. Naseem

    2009-08-20

    The transalkylation of 1,3,5-triethylbenzene (1,3,5-TEB) with ethylbenzene (EB) has been studied over USYtype catalysts using a riser simulator that mimics the operation of a fluidized-bed reactor. The reaction mixture EB and 1,3,5-TEB was used at a molar ratio of 1:1, which is equivalent to 40:60 wt % of EB/1,3,5-TEB, respectively. The reaction temperature was varied from 350 to 500 °C with a time on stream ranging from 3-15 s. The effect of reaction conditions on 1,3,5-TEB conversion, DEB selectivity, and isomerization of 1,3,5-TEB is reported. The transalkylation of 1,3,5-TEB with EB has been compared to the transformation reaction of pure 1,3,5-TEB and EB. The experimental results have revealed that reactivity of 1,3,5-TEB and selectivity of DEB is increased during the transalkylation reaction (EB + 1,3,5-TEB) as compared to the transformation reaction of pure EB or 1,3,5-TEB. The 1,3,5-TEB undergoes isomerization and a cracking reaction to produce DEB and EB but does not undergo any appreciable disproportionation reaction. The isomerization of 1,3,5-TEB is more active at low temperatures, while cracking is more active at high temperatures. © 2009 American Chemical Society.

  1. Reactivity of Cyclopentadienes Modified by Bis(3,5- dimethylpyrazol-l-yl)methyl Group to W(CO)5THF

    Institute of Scientific and Technical Information of China (English)

    张晓燕; 刘霞丽; 宋海斌; 唐良富

    2011-01-01

    The reactions of the mixture of 1- and 2-[2,2-bis(3,5-dimethylpyrazol-l-yl)-1-phenylethyl]-1,3-cyclopentadiene (bpzpcpH) and mixture of 1- and 2-[2,2-bis(3,5-dimethylpyrazol-l-yl)-I,l-diphenylethyl]-l,3-cyclopentadiene (bpzdpcpH) with W(CO)sTHF have been carried out. The former yields complex (bpzpcpH)W(CO)4, in which the bpzpcpH acts as a k2-(N,N) bidentate ligand, and the cyclopentadiene moiety does not participate in the coordination to the tungsten atom. While the latter gives complex (bpzdpcpH)W(CO)3, in which the cyclopentadiene moiety coordinates to the tungsten atom in η2-fashion instead of general η5-coordinated mode, causing bpzdpcpH to act as a tridentate k3-(π,N,N) ligand,

  2. Vibrational modes and Structure of Niobium(V) Oxosulfato Complexes in the Molten Nb2O5-K2S2O7-K2SO4 System Studied by Raman Spectroscopy

    DEFF Research Database (Denmark)

    Paulsen, Andreas L.; Borup, Flemming; Berg, Rolf W.

    2010-01-01

    The structural and vibrational properties of NbV oxosulfato complexes formed in Nb2O5-K2S2O7 and Nb2O5-K2S2O7-K2SO4 molten mixtures with 0 Raman spectroscopy under static equilibtrium at temperatures up to 700 °C. The spectral features...... for the binary Nb2O5-K2S2O7 molten system indicate that the dissolution of Nb2O5 proceeds with consumption of S2O7 leading to the formation of a NbV oxosulfato complex according to Nb2O5 + nS2O7 --> C2n-; a simple formalism exploiting the relative Raman band intensities is used for determining the stoichiometric...... coefficient, n, pointing to n = 3 and to the following reaction: Nb2O5 + 3S2O7 --> 2NbO(SO4)3, which is consistent with the Raman spectra of the molten mixtures. Nb2O5 could be dissolved much easier when K2SO4 was present in an equimolar (1:1) SO4/Nb ratio; the incremental presence of K2SO4 in Nb2O5-K2S2O7...

  3. Comparison of two new angiogenesis PET tracers 68Ga-NODAGA-E[c(RGDyK)]2 and 64Cu-NODAGA-E[c(RGDyK)]2; in vivo imaging studies in human xenograft tumors

    DEFF Research Database (Denmark)

    Oxbøl, Jytte; Brandt-Larsen, Malene; Schjøth-Eskesen, Christina

    2014-01-01

    . CONCLUSION: (68)Ga-NODAGA-E[c(RGDyK)](2) and (64)Cu-NODAGA-E[c(RGDyK)](2) can be easily synthesized and are both promising candidates for PET imaging of integrin αVβ3 positive tumor cells. (68)Ga-NODAGA-E[c(RGDyK)](2) showed slightly more stable tumor retention. With the advantage of in-house commercially......INTRODUCTION: The aim of this study was to synthesize and perform a side-by-side comparison of two new tumor-angiogenesis PET tracers (68)Ga-NODAGA-E[c(RGDyK)](2) and (64)Cu-NODAGA-E[c(RGDyK)](2) in vivo using human xenograft tumors in mice. Human radiation burden was estimated to evaluate...... potential for future use as clinical PET tracers for imaging of neo-angiogenesis. METHODS: A (68)Ge/(68)Ga generator was used for the synthesis of (68)Ga-NODAGA-E[c(RGDyK)](2). (68)Ga and (64)Cu labeled NODAGA-E[c(RGDyK)](2) tracers were administrated in nude mice bearing either human glioblastoma (U87MG...

  4. Optimization of fermentation conditions for vitamin K2 (MK-7) by response surface methodology%响应面法优化维生素K2(MK-7)发酵条件

    Institute of Scientific and Technical Information of China (English)

    严为留; 张伟国; 钱和

    2015-01-01

    对实验室保藏的一株维生素K 2(MK-7)高产菌的摇瓶发酵条件进行优化,结果表明菌体在静置培养状态下比在摇瓶培养状态下能够合成更多的维生素K 2;同时发现玉米粉经过高温淀粉酶液化之后非常适合作为合成维生素K 2的碳源。最后利用响应面法对发酵培养基中主要因素的最适宜水平及其交互作用进行了研究与探讨,优化后维生素K 2产量由7.09 mg·L -1提高到了67.22 mg·L -1 ,高于文献报道值。%The fermentation condition optimization procedure of a high vitamin K2 (MK-7)producing strain preserved in the laboratory was conducted for higher vitamin K2 production. The results showed that this strain could synthesize more vitamin K2 in static culture condition than that in shaking culture. And when the corn meal was liquefied by thermostable amylase,the liquified corn meal was very suitable for the synthesis of vitamin K 2 . At last,the response surface methodo-logy was applied to find the most appropriate level of major factors. After optimization the concentration of vitamin K2 reached as high as 67. 22 mg·L - 1 ,much higher than that without optimization of 7. 09 mg·L - 1 and the reported.

  5. (6E,8Z)-6,8-Pentadecadienal, a Novel Attractant Pheromone Produced by Males of the Cerambycid Beetles Chlorida festiva and Chlorida costata.

    Science.gov (United States)

    Silva, Weliton D; Millar, Jocelyn G; Hanks, Lawrence M; Bento, José Maurício S

    2016-10-01

    We report the identification, synthesis, and first field bioassays of a pheromone component with a novel structure produced by adult males of Chlorida festiva (L.) and Chlorida costata Audinet-Serville, longhorn beetle species in the subfamily Cerambycinae. Headspace volatiles from males contained a sex-specific compound that was identified as (6E,8Z)-6,8-pentadecadienal. Traps baited with this compound captured adults of both species and sexes, consistent with the aggregation-sex pheromones produced by males of many species in this subfamily. This compound represents a new structural class of cerambycid pheromones, and it is the first pheromone identified from species in the tribe Bothriospilini.

  6. The nuclear structure and related properties of some low-lying isomers of free-space O{sub n} clusters (n=6,8,12)

    Energy Technology Data Exchange (ETDEWEB)

    Forte, G. [Dipartimento di Scienze del Farmaco, Università di Catania, Viale A. Doria, 6, I-95126 Catania (Italy); Angilella, G.G.N., E-mail: giuseppe.angilella@ct.infn.it [Dipartimento di Fisica e Astronomia, Università di Catania, Via S. Sofia, 64, I-95123 Catania (Italy); Scuola Superiore di Catania, Università di Catania, Via Valdisavoia, 9, I-95123 Catania (Italy); CNISM, UdR Catania, Via S. Sofia, 64, I-95123 Catania (Italy); INFN, Sez. Catania, Via S. Sofia, 64, I-95123 Catania (Italy); March, N.H. [Department of Physics, University of Antwerp, Groenenborgerlaan, 171, B-2020 Antwerp (Belgium); Oxford University, Oxford (United Kingdom); Pucci, R. [Dipartimento di Fisica e Astronomia, Università di Catania, Via S. Sofia, 64, I-95123 Catania (Italy); CNISM, UdR Catania, Via S. Sofia, 64, I-95123 Catania (Italy)

    2013-04-01

    After some introductory comments relating to antiferromagnetism of crystalline O{sub 2}, and brief remarks on the geometry of ozone, Hartree–Fock (HF) theory plus second-order Møller–Plesset (MP2) corrections are used to predict the nuclear structure of low-lying isomers of free-space O{sub n} clusters, for n=6,8, and 12. The equilibrium nuclear–nuclear potential energy is also discussed in relation to the number n of oxygen atoms in the cluster.

  7. 41 CFR 102-3.5 - What does this subpart cover and how does it apply?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What does this subpart cover and how does it apply? 102-3.5 Section 102-3.5 Public Contracts and Property Management Federal...? § 102-3.5 What does this subpart cover and how does it apply? This subpart provides the policy...

  8. 3,5-二甲氧苯基己基酮的合成%Synthesis of 1-(3,5-Dimethoxyphenyl)-1-heptanone

    Institute of Scientific and Technical Information of China (English)

    徐玉明; 李年康; 徐新

    2012-01-01

    1-(3,5-Dimethoxyphenyl)-1-heptanone,an important intermediate for preparation of nabilone,was synthesized to form 3,5-Dimethoxybenzamide by cyanidation reaction and Grignard reaction.The better synthesis process conditions were that in cyanidation reaction: 0.2 moL 3,5-Dimethoxybenzamide as bench marks,adding time 2 h,w(NaOH)=50%,the solvent for chloroform,phase transfer catalyst for TEBA,the yield of 3,5-Dimethoxybenzamide was 74.39%,and in Grignard reaction: 0.25 moL 3,5-Dimethoxybenzonitrile as benchmark,Grignard reagent and 3,5-Dimethoxybenzonitrile molar ratio of 1.5:1,the backflow time for 12 h,the yield was 3,5-Dimethoxybenzonitrile was 92.1%.Two step total yield of 68.5%.The structures of the target product were confirmed by means of the boiling point and 1H NMR.%以3,5-二甲氧基苯甲酰胺为原料,经氰化反应,格式反应合成大麻隆的重要中间体-3,5-二甲氧苯基己基酮。较佳的合成工艺条件为:(1)腈基化反应:以0.2 mol 3,5-二甲氧基苯甲酰胺为基准,滴加时间2 h,质量分数(NaOH)=50%,溶剂为氯仿,相转移催化剂为TEBA,反应收率为74.39%;(2)格式反应:以0.25 mol 3,5-二甲氧基苯甲腈为基准,正溴己烷格氏试剂四氢呋喃溶液与3,5-二甲氧基苯甲腈的摩尔比为1.5∶1,回流时间为12 h,反应收率为92.1%。两步反应总收率为68.5%。通过熔点,沸点,1H NMR确证目标产物的化学结构。

  9. The K2-ESPRINT Project V: A Short-period Giant Planet Orbiting a Subgiant Star*

    Science.gov (United States)

    Van Eylen, Vincent; Albrecht, Simon; Gandolfi, Davide; Dai, Fei; Winn, Joshua N.; Hirano, Teriyuki; Narita, Norio; Bruntt, Hans; Prieto-Arranz, Jorge; Béjar, Víctor J. S.; Nowak, Grzegorz; Lund, Mikkel N.; Palle, Enric; Ribas, Ignasi; Sanchis-Ojeda, Roberto; Yu, Liang; Arriagada, Pamela; Butler, R. Paul; Crane, Jeffrey D.; Handberg, Rasmus; Deeg, Hans; Jessen-Hansen, Jens; Johnson, John A.; Nespral, David; Rogers, Leslie; Ryu, Tsuguru; Shectman, Stephen; Shrotriya, Tushar; Slumstrup, Ditte; Takeda, Yoichi; Teske, Johanna; Thompson, Ian; Vanderburg, Andrew; Wittenmyer, Robert

    2016-11-01

    We report on the discovery and characterization of the transiting planet K2-39b (EPIC 206247743b). With an orbital period of 4.6 days, it is the shortest-period planet orbiting a subgiant star known to date. Such planets are rare, with only a handful of known cases. The reason for this is poorly understood but may reflect differences in planet occurrence around the relatively high-mass stars that have been surveyed, or may be the result of tidal destruction of such planets. K2-39 (EPIC 206247743) is an evolved star with a spectroscopically derived stellar radius and mass of {3.88}-0.42+0.48 {R}ȯ and {1.53}-0.12+0.13 {M}ȯ , respectively, and a very close-in transiting planet, with a/{R}\\star =3.4. Radial velocity (RV) follow-up using the HARPS, FIES, and PFS instruments leads to a planetary mass of {50.3}-9.4+9.7 {M}\\oplus . In combination with a radius measurement of 8.3+/- 1.1 {R}\\oplus , this results in a mean planetary density of {0.50}-0.17+0.29 g cm‑3. We furthermore discover a long-term RV trend, which may be caused by a long-period planet or stellar companion. Because K2-39b has a short orbital period, its existence makes it seem unlikely that tidal destruction is wholly responsible for the differences in planet populations around subgiant and main-sequence stars. Future monitoring of the transits of this system may enable the detection of period decay and constrain the tidal dissipation rates of subgiant stars. Based on observations made with the NOT telescope under program ID. 50-022/51-503, 50-213(CAT), 52-201 (CAT), 52-108 (OPTICON), 51-211 (CAT), and ESOs 3.6 m telescope at the La Silla Paranal Observatory under program ID 095.C-0718(A).

  10. That's How We Roll - The NASA K2 Mission Science Planning, Products, and Performance Metrics

    Science.gov (United States)

    Van Cleve, Jeffrey E.; Howell, Steve B.; Smith, Jeffrey C.; Clarke, Bruce; Thompson, Susan E.; Bryson, Steve; Lund, Mikkel N.; Handberg, Rasmus; Chaplin, William J.; Kepler Science Office, Kepler Science Operations Center, Ball Aerospace, U. Colorado LASP

    2016-06-01

    NASA’s exoplanet Discovery mission Kepler was reconstituted as the K2 mission a year after the failure of the 2nd of Kepler’s 4 reaction wheels in May 2013. The new spacecraft pointing method now gives typical roll motion of 1.0 pixels peak-to-peak over 6 hours at the edges of the field, two orders of magnitude greater than for Kepler. Despite these roll errors, the flight system and its modified data processing pipeline restores much of the photometric precision of the primary mission while viewing a wide variety of targets, thus turning adversity into diversity. We define metrics for data compression and pixel budget available in each campaign; the photometric noise on exoplanet transit and stellar activity time scales; residual correlations in corrected long cadence light curves; and the protection of test sinusoidal signals from overfitting in the systematic error removal process. We find that data compression and noise both increase linearly with radial distance from the center of the field of view, while the data compression also increases as the square root of star count. For sufficiently dense star fields, such as the Galactic Center, the data entropy so high that Huffman compression is ineffective and only requantization is used. At the FOV center, where roll motion is nearly negligible, the limiting 6 hour photometric precision for a quiet 12th magnitude star can be as low as 30 ppm, only 25% higher than that of Kepler. This noise performance is achieved without sacrificing signal fidelity; test sinusoids injected into the data are attenuated by less than 10% for signals with periods up 15 days. At time scales relevant to asteroseismology, light curves derived from K2 archive calibrated pixels have high-frequency noise amplitude within 40% of that achieved by Kepler. These improvements follow from the data analysis efforts of Kepler Science Operation Center and Kepler Science Office, and from the operational improvements developed by Ball Aerospace

  11. Klebsiella phage vB_KleM-RaK2 - a giant singleton virus of the family Myoviridae.

    Directory of Open Access Journals (Sweden)

    Eugenijus Simoliūnas

    Full Text Available At 346 kbp in size, the genome of a jumbo bacteriophage vB_KleM-RaK2 (RaK2 is the largest Klebsiella infecting myovirus genome sequenced to date. In total, 272 out of 534 RaK2 ORFs lack detectable database homologues. Based on the similarity to biologically defined proteins and/or MS/MS analysis, 117 of RaK2 ORFs were given a functional annotation, including 28 RaK2 ORFs coding for structural proteins that have no reliable homologues to annotated structural proteins in other organisms. The electron micrographs revealed elaborate spike-like structures on the tail fibers of Rak2, suggesting that this phage is an atypical myovirus. While head and tail proteins of RaK2 are mostly myoviridae-related, the bioinformatics analysis indicate that tail fibers/spikes of this phage are formed from podovirus-like peptides predominantly. Overall, these results provide evidence that bacteriophage RaK2 differs profoundly from previously studied viruses of the Myoviridae family.

  12. Spitzer Observations Confirm and Rescue the Habitable-zone Super-Earth K2-18b for Future Characterization

    Science.gov (United States)

    Benneke, Björn; Werner, Michael; Petigura, Erik; Knutson, Heather; Dressing, Courtney; Crossfield, Ian J. M.; Schlieder, Joshua E.; Livingston, John; Beichman, Charles; Christiansen, Jessie; Krick, Jessica; Gorjian, Varoujan; Howard, Andrew W.; Sinukoff, Evan; Ciardi, David R.; Akeson, Rachel L.

    2017-01-01

    The recent detections of two transit events attributed to the super-Earth candidate K2-18b have provided the unprecedented prospect of spectroscopically studying a habitable-zone planet outside the solar system. Orbiting a nearby M2.5 dwarf and receiving virtually the same stellar insolation as Earth, K2-18b would be a prime candidate for the first detailed atmospheric characterization of a habitable-zone exoplanet using the Hubble Space Telescope (HST)and James Webb Space Telescope (JWST). Here, we report the detection of a third transit of K2-18b near the predicted transit time using the Spitzer Space Telescope. The Spitzer detection demonstrates the periodic nature of the two transit events discovered by K2, confirming that K2-18 is indeed orbited by a super-Earth in a 33 day orbit, ruling out the alternative scenario of two similarly sized, long-period planets transiting only once within the 75 day Kepler Space Telescope (K2) observation. We also find, however, that the transit event detected by Spitzer occurred 1.85 hr (7σ ) before the predicted transit time. Our joint analysis of the Spitzer and K2 photometry reveals that this early occurrence of the transit is not caused by transit timing variations, but the result of an inaccurate ephemeris due to a previously undetected data anomaly in the K2 photometry. We refit the ephemeris and find that K2-18b would have been lost for future atmospheric characterizations with HST and JWST if we had not secured its ephemeris shortly after the discovery. We caution that immediate follow-up observations as presented here will also be critical for confirming and securing future planets discovered by the Transiting Exoplanet Survey Satellite (TESS), in particular if only two transit events are covered by the relatively short 27-day TESS campaigns.

  13. 双生型动派 东风悦达起亚KIA K2

    Institute of Scientific and Technical Information of China (English)

    诸葛; 有劲(摄影)

    2012-01-01

    专为中国市场打造的两厢版K2此次又占了个“全球首发”的噱头。与孪生兄弟不同的是,它是彼得·希瑞尔操刀的起亚首款两厢掀背轿车,并且会在东欧市场销售。“Design KIA”设计风潮引领下的全新家族式外形正在被中国消费着广泛接纳,那么这款去掉尾巴的小兽是否能续与同族的辉煌呢?

  14. Oxygen-deficient GdK2Nb5O15 ferroelectric epitaxial thin film

    Science.gov (United States)

    Allouche, B.; Gagou, Y.; Le Marrec, F.; Fremy, M.-A.; El Marssi, M.

    2016-12-01

    The ferroelectric compound GdK2Nb5O15 (GKN) thin film with tetragonal-tungsten-bronze–type structure was grown by pulsed-laser deposition on (001)SrRuO3/La0.5Sr0.5CoO3/MgO substrate. Using X-ray diffraction analysis we demonstrate that the phase transition temperature in the GKN thin film was shifted to high temperatures due to substrate-induced stress. Impedance spectroscopy investigations show Maxwell-Wagner–type conduction at low frequencies, which leads to resistive switching. Oxygen vacancies and temperature effects were studied to highlight the stability of the resistive switching behavior in the GKN thin film.

  15. Spice/K2 drugs--more than innocent substitutes for marijuana.

    Science.gov (United States)

    Zawilska, Jolanta B; Wojcieszak, Jakub

    2014-03-01

    Smokeable herbal mixtures containing synthetic agonists of cannabinoid receptors, known under brand names such as Spice, K2 and Kronic, represent a relatively new type of designer psychoactive drugs that has recently emerged on the recreational drug market. Although the Spice packages are labelled 'not for human consumption' or 'for aromatherapy only' and declared to be purely herbal, these herbal mixtures produce cannabis-like effects after smoking. This review surveys the current state of knowledge regarding the pharmacological properties of synthetic cannabimimetics and the prevalence and pattern of their use. Special emphasis is given to the negative consequences of using these products, including, among others, hallucinations, psychoses with delusions, seizures, cardiovascular symptoms and acute kidney injury.

  16. VizieR Online Data Catalog: Broadband photometry of Neptune from K2 (Rowe+, 2017)

    Science.gov (United States)

    Rowe, J. F.; Gaulme, P.; Lissauer, J. J.; Marley, M. S.; Simon, A. A.; Hammel, H. B.; Silva Aguirre, V.; Barclay, T.; Benomar, O.; Boumier, P.; Caldwell, D. A.; Casewell, S. L.; Chaplin, W. J.; Colon, K. D.; Corsaro, E.; Davies, G. R.; Fortney, J. J.; Garcia, R. A.; Gizis, J. E.; Haas, M. R.; Mosser, B.; Schmider, F.-X.

    2017-08-01

    The K2 C3 field provided the first opportunity to observe the planet Neptune for up to 80 days with short-cadence (1 minute) sampling (the C3 campaign had an actual duration of 69.2 days, limited by on-board data storage). We were awarded sufficient pixel allocation from Guest Observer Programs GO3060 (PI: Rowe) and GO3057 (PI: Gaulme) to continuously monitor Neptune for 49 days. Short-cadence target pixel files were obtained from Mikulski Archive for Space Telescopes (MAST). The Neptune short-cadence subraster was spread across 161 FITS files. Each file contained 1 column of time-series pixel data. Each target pixel file contains observations starting on 2014 November 15 and finishing on 2015 January 18. (1 data file).

  17. Kinesis K2 太阳能/风能充电器

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    这款Kinesis K2太阳能/风力两用充电器主要提供USB插槽供电,给充电器一小时的太阳能充电或者风力充电,你就可以得到持续通话30分钟的电量。充电器侧面的LED灯提示你,电池还有多少电量剩余.这个充电器可以横着摆放.也可以竖着摆放,底部有个夹子,

  18. Origins of the k(-2) spectrum in decaying Taylor-Green magnetohydrodynamic turbulent flows.

    Science.gov (United States)

    Dallas, V; Alexakis, A

    2013-11-01

    We investigate the origins of k(-2) spectrum in a decaying Taylor-Green magnetohydrodynamic flow with zero large scale magnetic flux that was reported by Lee et al. [Phys. Rev. E 81, 016318 (2010)]. So far, a possible candidate for this scaling exponent has been the weak turbulence phenomenology. From our numerical simulations, we observe that current sheets in the magnetic Taylor-Green flow are formed in regions of magnetic discontinuities. Based on this observation and by studying the influence of the current sheets on the energy spectrum, using a filtering technique, we argue that the discontinuities are responsible for the -2 power law scaling of the energy spectra of this flow.

  19. Oxidation of benzyl alcohol by K2FeO4 to benzaldehyde over zeolites

    Science.gov (United States)

    Wang, Yuan-Yuan; Song, Hua; Song, Hua-Lin; Jin, Zai-Shun

    2016-10-01

    A novel and green procedure for benzaldehyde synthesis by potassium ferrate oxidation of benzyl alcohol employing zeolite catalysts was studied. The prepared oxidant was characterized by SEM and XRD. The catalytic activity of various solid catalysts was studied using benzyl alcohol as a model compound. USY was found to be a very efficient catalyst for this particular oxidation process. Benzaldehyde yields up to 96.0% could be obtained at the following optimal conditions: 0.2 mL of benzyl alcohol, 4 mmol of K2FeO4, 0.5 g of USY zeolite; 20 mL of cyclohexene, 0.3 mL of acetic acid (36 wt %), 30°C temperature, 4 h reaction time.

  20. HII 2407: A Low-Mass Eclipsing Binary Revealed by K2 Observations of the Pleiades

    CERN Document Server

    David, Trevor J; Hillenbrand, Lynne A; Cody, Ann Marie; Conroy, Kyle; Stassun, Keivan G; Pope, Benjamin; Aigrain, Suzanne; Gillen, Ed; Cameron, Andrew Collier; Barrado, David; Rebull, L M; Isaacson, Howard; Marcy, Geoffrey W; Zhang, Celia; Riddle, Reed L; Ziegler, Carl; Law, Nicholas M; Baranec, Christoph

    2015-01-01

    The star HII 2407 is a member of the relatively young Pleiades star cluster and was previously discovered to be a single-lined spectroscopic binary. It is newly identified here within $Kepler$/$K2$ photometric time series data as an eclipsing binary system. Mutual fitting of the radial velocity and photometric data leads to an orbital solution and constraints on fundamental stellar parameters. While the primary has arrived on the main sequence, the secondary is still pre-main-sequence and we compare our results for the $M/M_\\odot$ and $R/R_\\odot$ values with stellar evolutionary models. We also demonstrate that the system is likely to be tidally synchronized. Follow-up infrared spectroscopy is likely to reveal the lines of the secondary, allowing for dynamically measured masses and elevating the system to benchmark eclipsing binary status.

  1. Detailed study of dissipative quantum dynamics of K-2 attached to helium nanodroplets

    CERN Document Server

    Schlesinger, Martin

    2011-01-01

    We thoroughly investigate vibrational quantum dynamics of dimers attached to He droplets motivated by recent measurements with K-2 [1]. For those femtosecond pump-probe experiments, crucial observed features are not reproduced by gas phase calculations but agreement is found using a description based on dissipative quantum dynamics, as briefly shown in [2]. Here we present a detailed study of the influence of possible effects induced by the droplet. The helium droplet causes electronic decoherence, shifts of potential surfaces, and relaxation of wave packets in attached dimers. Moreover, a realistic description of (stochastic) desorption of dimers off the droplet needs to be taken into account. Step by step we include and study the importance of these effects in our full quantum calculation. This allows us to reproduce and explain all major experimental findings. We find that desorption is fast and occurs already within 2-10 ps after electronic excitation. A further finding is that slow vibrational motion in ...

  2. Phase composition of cathodic deposits synthesized in flinak-k2taf7-kbf4 melt

    Directory of Open Access Journals (Sweden)

    Makarova O.V.

    2003-01-01

    Full Text Available The phase composition of cathodic deposits synthesized from FLINAK-K2TaF7-KBF4 melt has been studied by the X-ray diffraction method. It is shown that boron content in the electrodeposit grows as the cathodic potential is increased from peak R1 to peak R4 in the voltammogram. The scheme of changes in the phase composition depending on the increasing current density is given as follows: {β-Ta + Ta2B}R1 → {β-Ta + (Ta3B4 TaB}R2 → {TaB2}R3 → {TaB2 + B}R4.

  3. HII 2407: AN ECLIPSING BINARY REVEALED BY K2 OBSERVATIONS OF THE PLEIADES

    Energy Technology Data Exchange (ETDEWEB)

    David, Trevor J.; Hillenbrand, Lynne A.; Zhang, Celia; Riddle, Reed L. [Department of Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States); Stauffer, John; Rebull, L. M. [Spitzer Science Center, California Institute of Technology, Pasadena, CA 91125 (United States); Cody, Ann Marie [NASA Ames Research Center, Mountain View, CA 94035 (United States); Conroy, Kyle; Stassun, Keivan G. [Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235 (United States); Pope, Benjamin; Aigrain, Suzanne; Gillen, Ed [Department of Physics, University of Oxford, Keble Road, Oxford OX1 3RH (United Kingdom); Cameron, Andrew Collier [SUPA, School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, Fife KY16 9SS (United Kingdom); Barrado, David [Centro de Astrobiología, INTA-CSIC, Dpto. Astrofísica, ESAC Campus, P.O. Box 78, E-28691 Villanueva de la Cañada, Madrid (Spain); Isaacson, Howard; Marcy, Geoffrey W. [Department of Astronomy, University of California, Berkeley, CA 94720 (United States); Ziegler, Carl; Law, Nicholas M. [Department of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3255 (United States); Baranec, Christoph, E-mail: tjd@astro.caltech.edu [Institute for Astronomy, University of Hawai‘i at Mānoa, Hilo, HI 96720-2700 (United States)

    2015-11-20

    The star HII 2407 is a member of the relatively young Pleiades star cluster and was previously discovered to be a single-lined spectroscopic binary. It is newly identified here within Kepler/K2 photometric time series data as an eclipsing binary system. Mutual fitting of the radial velocity and photometric data leads to an orbital solution and constraints on fundamental stellar parameters. While the primary has arrived on the main sequence, the secondary is still pre-main sequence and we compare our results for the M/M{sub ⊙} and R/R{sub ⊙} values with stellar evolutionary models. We also demonstrate that the system is likely to be tidally synchronized. Follow-up infrared spectroscopy is likely to reveal the lines of the secondary, allowing for dynamically measured masses and elevating the system to benchmark eclipsing binary status.

  4. Characterizing K2 Planet Discoveries: A Super-Earth Transiting the Bright K Dwarf HIP 116454

    OpenAIRE

    Vanderburg, A.; Montet, BT; Johnson, JA; Buchhave, LA; Zeng, L.; Pepe, F.; Cameron, AC; Latham, DW; Molinari, E.; Udry, S.; Lovis, C; Matthews, JM; Cameron, C; Law, N; Bowler, BP

    2015-01-01

    We report the first planet discovery from the two-wheeled Kepler (K2) mission: HIP 116454 b. The host star HIP 116454 is a bright (V = 10.1, K = 8.0) K1 dwarf with high proper motion and a parallax-based distance of 55.2 ± 5.4 pc. Based on high-resolution optical spectroscopy, we find that the host star is metal-poor with [Fe/H] =–0.16 ± 0.08 and has a radius R = 0.716 ± 0.024 R ☉ and mass M = 0.775 ± 0.027 M ☉. The star was observed by the Kepler spacecraft during its Two-Wheeled Concept Eng...

  5. Examining the Flicker-Jitter Relation of K2 stars: the Dependence on Chromospheric Activity

    Science.gov (United States)

    Luhn, Jacob K.; Bastien, Fabienne A.; Wright, Jason

    2017-01-01

    Recently, Bastien et al. (2014) have shown that short timescale photometric variations from high-precision Kepler light curves, coined "flicker", can be linked to radial velocity (RV) noise, or "jitter", in chromospherically inactive stars. Observations of the sun show invariance in flicker over its 11-year activity cycle. Therefore, we seek to examine how well the relation holds for more active stars. Here we explore the relation between photometric flicker and RV jitter by extending the sample to stars observed by the recent K2 mission for which data have been released (Campaigns 0-8). The initial Kepler sample included 12 stars with surface gravities 3 TESS and other future telescopes which will produce high-precision light curves.

  6. Water permeability of Na+-K+-2C1- cotransporters in mammalian epithelial cells

    DEFF Research Database (Denmark)

    Hammann, Steffen; Herrera-Perez, J.J.; Bundgaard, Magnus

    2005-01-01

    Water transport properties of the Na+-K+-2Cl- cotransporter (NKCC) were studied in cultures of pigmented epithelial cells (PE) from the ciliary body of the eye. Here, the membrane that faces upwards contains NKCCs and can be subjected to rapid changes in bathing solution composition and osmolarity...... changes of the cotransporter and interaction with Na+, K+ and Cl-. Similar measurements were performed on immortalized cell cultures from the thick ascending limb of the loop of Henle (TALH). Given similar overall transport rates of bumetanide-sensitive 86Rb+, the NKCCs of this tissue did not contribute...... any bumetanide-sensitive Lp. This suggests that the cotransporters of the two tissues are either different isoforms or the same cotransporter but in two different transport modes....

  7. K2 Rotation Periods for Low-mass Hyads and the Implications for Gyrochronology

    Science.gov (United States)

    Douglas, S. T.; Agüeros, M. A.; Covey, K. R.; Cargile, P. A.; Barclay, T.; Cody, A.; Howell, S. B.; Kopytova, T.

    2016-05-01

    As the closest open cluster to the Sun, the Hyades is an important benchmark for many stellar properties, but its members are also scattered widely over the sky. Previous studies of stellar rotation in the Hyades relied on targeted observations of single stars or data from shallower all-sky variability surveys. The re-purposed Kepler mission, K2, is the first opportunity to measure rotation periods (P rot) for many Hyads simultaneously while also being sensitive to fully convective M dwarf members. We analyze K2 data for 65 Hyads and present P rot values for 48. Thirty-seven of these are new measurements, including the first P rot measurements for fully convective Hyads. For 9 of the 11 stars with P rot in the literature and this work, the measurements are consistent; we attribute the two discrepant cases to spot evolution. Nearly all stars with masses ≲0.3 M ⊙ are rapidly rotating, indicating a change in rotation properties at the boundary to full convection. When confirmed and candidate binaries are removed from the mass-period plane, only three rapid rotators with masses ≳0.3 M ⊙ remain. This is in contrast to previous results showing that the single-valued mass-period sequence for ≈600 Myr old stars ends at ≈0.65 M ⊙ when binaries are included. We also find that models of rotational evolution predict faster rotation than is actually observed at ≈600 Myr for stars ≲0.9 M ⊙. The dearth of single rapid rotators more massive than ≈0.3 M ⊙ indicates that magnetic braking is more efficient than previously thought, and that age-rotation studies must account for multiplicity.

  8. The K2 Galactic Archaeology Program Data Release. I. Asteroseismic Results from Campaign 1

    Science.gov (United States)

    Stello, Dennis; Zinn, Joel; Elsworth, Yvonne; Garcia, Rafael A.; Kallinger, Thomas; Mathur, Savita; Mosser, Benoit; Sharma, Sanjib; Chaplin, William J.; Davies, Guy; Huber, Daniel; Jones, Caitlin D.; Miglio, Andrea; Silva Aguirre, Victor

    2017-01-01

    NASA's K2 mission is observing tens of thousands of stars along the ecliptic, providing data suitable for large-scale asteroseismic analyses to inform galactic archaeology studies. Its first campaign covered a field near the north Galactic cap, a region never covered before by large asteroseismic-ensemble investigations, and was therefore of particular interest for exploring this part of our Galaxy. Here we report the asteroseismic analysis of all stars selected by the K2 Galactic Archaeology Program during the mission's “north Galactic cap” campaign 1. Our consolidated analysis uses six independent methods to measure the global seismic properties, in particular the large frequency separation and the frequency of maximum power. From the full target sample of 8630 stars we find about 1200 oscillating red giants, a number comparable with estimates from galactic synthesis modeling. Thus, as a valuable by-product we find roughly 7500 stars to be dwarfs, which provide a sample well suited for galactic exoplanet occurrence studies because they originate from our simple and easily reproducible selection function. In addition, to facilitate the full potential of the data set for galactic archaeology, we assess the detection completeness of our sample of oscillating red giants. We find that the sample is at least nearly complete for stars with 40 ≲ {ν }\\max /μHz ≲ 270 and {ν }\\max ,{detect}< 2.6× {10}6\\cdot {2}-{\\text{Kp}} μHz. There is a detection bias against helium core burning stars with {ν }\\max ∼ 30 μHz, affecting the number of measurements of {{Δ }}ν and possibly also {ν }\\max . Although we can detect oscillations down to {\\text{Kp}} = 15, our campaign 1 sample lacks enough faint giants to assess the detection completeness for stars fainter than {\\text{Kp}} ∼ 14.5.

  9. Effects of Vitamin K2 on the Development of Osteopenia in Rats as the Models of Osteoporosis

    OpenAIRE

    Iwamoto, Jun; Takeda, Tsuyoshi; Sato, Yoshihiro

    2006-01-01

    Vitamin K2 is widely used for the treatment of osteoporosis in Japan. To understand the effects of vitamin K2 on bone mass and bone metabolism, we reviewed its effects on the development of osteopenia in rats, which characterizes models of osteoporosis. Vitamin K2 was found to attenuate the increase in bone resorption and/or maintain bone formation, reduce bone loss, protect against the loss of trabecular bone mass and its connectivity, and prevent the decrease in strength of the long bone in...

  10. PARTICIPACION DEL COMPLEJO PIRUVATO DESHIDROGENASA DE AEROMONAS CAVIAE ST EN RESISTENCIA TELURITO DE POSTASIO (K2TEO3)

    OpenAIRE

    2008-01-01

    El telurito de potasio (K2TeO3) es altamente tóxico para la mayoría de los seres vivos. Aunque se desconoce el mecanismo de toxicidad especifico, recientemente se ha demostrado que estaría dado, al menos en parte, por el establecimiento de un estrés oxidativo. Aeromonas caviae ST, el microorganismo utilizado en este estudio es altamente resistente a K2TeO3 y extractos crudos de esta bacteria catalizan la reducción de K2TeO3 in vitro. Se obtuvo fracciones con actividad telurito reductasa qu...

  11. Role of Nitrogen Limitation in Transformation of RDX (Hexahydro-1,3,5-Trinitro-1,3,5-Triazine) by Gordonia sp. Strain KTR9

    Science.gov (United States)

    Hancock, Dawn E.; Jung, Carina M.; Eberly, Jed O.; Mohn, William W.; Eltis, Lindsay D.; Crocker, Fiona H.

    2013-01-01

    The transcriptome of RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine)-degrading strain Gordonia sp. strain KTR9 and its glnR mutant were studied as a function of nitrogen availability to further investigate the observed ammonium-mediated inhibition of RDX degradation. The results indicate that nitrogen availability is a major determinant of RDX degradation and xplA gene expression in KTR9. PMID:23275513

  12. Equilibrium drug solubility measurements in 96-well plates reveal similar drug solubilities in phosphate buffer pH 6.8 and human intestinal fluid.

    Science.gov (United States)

    Heikkilä, Tiina; Karjalainen, Milja; Ojala, Krista; Partola, Kirsi; Lammert, Frank; Augustijns, Patrick; Urtti, Arto; Yliperttula, Marjo; Peltonen, Leena; Hirvonen, Jouni

    2011-02-28

    This study was conducted to develop a high throughput screening (HTS) method for the assessment of equilibrium solubility of drugs. Solid-state compounds were precipitated from methanol in 96-well plates, in order to eliminate the effect of co-solvent. Solubility of twenty model drugs was analyzed in water and aqueous solutions (pH 1.2 and 6.8) in 96-well plates and in shake-flasks (UV detection). The results obtained with the 96-well plate method correlated well (R(2)=0.93) between the shake-flask and 96-well plates over the wide concentration scale of 0.002-169.2mg/ml. Thereafter, the solubility tests in 96-well plates were performed using fasted state human intestinal fluid (HIF) from duodenum of healthy volunteers. The values of solubility were similar in phosphate buffer solution (pH 6.8) and HIF over the solubility range of 10(2)-10(5)μg/ml. The new 96-well plate method is useful for the screening of equilibrium drug solubility during the drug discovery process and it also allows the use of human intestinal fluid in solubility screening.

  13. The Effects of Bromides in Catalytic Hydrogenolysis Debenzylation of 2,4,6,8,10,12-Hexabenzyl-2,4,6,8,10,12-hexaazaisowurtzitane(HBIW)%溴化物在催化氢解脱苄中的作用

    Institute of Scientific and Technical Information of China (English)

    陈江涛; 欧育湘; 郑福平; 李博; 陈博仁

    1999-01-01

      This work deals with the effects ten of bromides and iodobenzene in catalytic hydrogenolysis debenzylation of 2,4,6,8,10,12-Hexabenzyl-2,4,6,8,10,12-hexaazaisowurtzitane(HBIW).It is proved that the addition of bromides leads to the decrease of the amount of catalyst needed and the increase of the yield of 2,6,8,12-tetraacetyl-4,10-dibenzyl-2,4,6,8,10,12- hexaazaisowurtzitane(TADBIW).While iodobenzene has adverse effects to the reaction system. The experimental data are reported in detail,and the mechanisms of debenzylation and bromides functions are discussed in this paper.%  研究了溴苯等10种溴化物及碘苯在六苄基六氮杂异伍兹烷(HBIW)催化氢解脱苄中的作用。结果表明:在反应体系中添加这些溴化物能使催化剂用量降低,反应时间缩短,产品得率提高,但碘苯对反应有副作用。本文报道了详细的实验数据,并讨论了溴化物的作用机理。

  14. Carbonates-based noble metal-free lean NOx trap catalysts MOx-K2CO3/K2Ti8O17 (M = Ce, Fe, Cu, Co) with superior catalytic performance

    Science.gov (United States)

    Zhang, Yuxia; You, Rui; Liu, Dongsheng; Liu, Cheng; Li, Xingang; Tian, Ye; Jiang, Zheng; Zhang, Shuo; Huang, Yuying; Zha, Yuqing; Meng, Ming

    2015-12-01

    A series of base metal-based lean NOx trap (LNT) catalysts MOx-K2CO3/K2Ti8O17 (M = Ce, Fe, Cu, Co) were synthesized by successive impregnations and employed for the storage and reduction of NOx in the emissions of lean-burn engines at 350 °C. The XRD and XANES/EXAFS results reveal that the active phases in the corresponding catalysts exist as CeO2, Fe2O3, CuO and Co3O4, respectively. Among all the catalysts, CoOx-K2CO3/K2Ti8O17 exhibits the best performance, which cannot only trap the NOx quickly and completely at lean condition, giving the highest storage capacity (3.32 mmol/g) reported so far, but also reduce the NOx at rich condition, showing a NOx reduction percentage as high as 99.0%. Meanwhile, this catalyst displays an ultralow NOx to N2O selectivity (0.3%) during NOx reduction. The excellent performance of CoOx-K2CO3/K2Ti8O17 results from its largest amount of surface active oxygen species as revealed by XPS, O2-TPD and NO-TPD. HRTEM, FT-IR and CO2-TPD results illustrate that several kinds of K species such as sbnd OK groups, K2O, surface carbonates and bulk or bulk-like carbonates coexist in the catalysts. Based upon the in situ DRIFTS results, the participation of K2CO3 in NOx storage is confirmed, and the predominant NOx storage species is revealed as bidentate nitrites formed via multiple kinetic pathways. The low cost and high catalytic performance of the CoOx-based LNT catalyst make it most promising for the substitution of noble metal-based LNT catalysts.

  15. Synthesis and enzymic activity of various substituted pyrazolo[1,5-a]-1,3,5-triazines as adenosine cyclic 3',5'-phosphate phosphodiesterase inhibitors.

    Science.gov (United States)

    Senga, K; O'Brien, D E; Scholten, M B; Novinson, T; Miller, J P; Robins, R K

    1982-03-01

    A series of various pyrazolo[1,5-a]-1,3,5-triazines have been prepared and studied as inhibitors of cAMP phosphodiesterase isolated from bovine brain, bovine heart, and rabbit lung. A number of compounds were found to be superior to theophylline. 2-Ethyl-7-phenylpyrazolo[1,5-a]-1,3,5-triazine (35) was found to be 97 times more potent than theophylline as an inhibitor of bovine brain PDE. 8-Bromo-2,4-dimethyl-7-phenylpyrazolo[1,5-a]-1,3,5-triazine (52) showed alpha lung = 40 compared to alpha heart = 3.0. Thus, various substituents could increase or decrease the inhibition relative to the type and source of tissue from which the PDE was isolated. The most active compound was 8-bromo-4-(diethylamino)-7-phenylpyrazolo[1,3-a]-1,3,5-triazine (25), which was 185 times more potent than theophylline as an inhibitor of PDE isolated from rabbit lung. The stepwise synthesis via ring-closure procedures of requisite pyrazole intermediates, followed by electrophilic substitution in the pyrazole ring and/or nucleophilic substitution in the 1,3,5-triazine moiety, resulted in the various pyrazolo[1,5-a]1,3,5-triazines listed in Tables I and II. Structure-activity relationships are reviewed.

  16. Influence of calcination atmosphere on photocatalytic reactivity of K2La2Ti3O10 for water splitting

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The layered perovskite type oxide K2La2Ti3O10 powders were prepared under air, Ar and H2 calcination atmospheres by sol-gel method and characterized by X-ray diffractometry, UV-Vis diffuse reflectance and X-ray photoelectron spectroscopy. The influence of the calcination atmosphere on the photocatalytic reactivity of K2La2Ti3O10 for hydrogen production was investigated.The photocatalytic reactivity of K2La2Ti3O10 prepared under air, Ar and H2 atmospheres was compared with that prepared under ultraviolet and visible light radiation using I- as electronic donor. The results show that K2La2Ti3O10 prepared under Ar and H2atmospheres has higher photocatalytic activity for hydrogen production than that prepared under air atmosphere. The hydrogen

  17. Silicon electrodeposition from chloride-fluoride melts containing K2SiF6 and SiO2

    Directory of Open Access Journals (Sweden)

    Zhuk Sergey I.

    2017-01-01

    Full Text Available Silicon electrodeposition on glassy carbon from the KF-KCl-K2SiF6, KF-KCl-K2SiF6-KOH and KF-KCl-K2SiF6-SiO2 melts was studied by the cyclic voltammetry. Тhe electroreduction of Si(IV to metallic Si was observed as a single 4-electron wave under all considered conditions. The reactions of cathode reduction of silicon from fluoride and oxyfluoride complexes were suggested. It was shown that the process can be controlled by the preliminary transformation of SiO44- to SiF62- and SiOxFyz-. The influence of the current density on structure and morphology of silicon deposits obtained during galvanostatic electrolysis of the KF-KCl-K2SiF6-SiO2 melt was studied.

  18. Benzene-1,3,5-tri-carb-oxy-lic acid-pyridinium-2-olate (1/3).

    Science.gov (United States)

    Campos-Gaxiola, José J; Zamora Falcon, Felipe; Corral Higuera, Ramón; Höpfl, Herbert; Cruz-Enríquez, Adriana

    2014-04-01

    The asymmetric unit of the title compound, C9H6O6·3C5H5NO, contains one benzene-1,3,5-tri-carb-oxy-lic acid mol-ecule (BTA) and three pyridin-2-ol mol-ecules each present in the zwitterion form. In the crystal, these entities are linked through O-H⋯O(-) and N(+)-H⋯O(-) hydrogen bonds, forming sheets parallel to (10-1). These layers contain macrocyclic rings of composition [BTA]2[pyol]6 and with graph-set notation R (6) 8(44), which are stacked along c through π-π inter-actions [inter-centroid distances = 3.536 (2)-3.948 (3) Å]. They are inter-connected by N(+)-H⋯O(-) hydrogen-bonded chains of pyridin-2-ol mol-ecules running parallel to c, forming a three-dimensional network. There are also C-H⋯O hydrogen bonds present which reinforce the three-dimensional structure.

  19. 9-{[4-(Dimethylaminobenzyl]amino}-5-(4-hydroxy-3,5-dimethoxyphenyl-5,5a,8a,9-tetrahydrofuro[3′,4′:6,7]naphtho[2,3-d][1,3]dioxol-6(8H-one methanol monosolvate

    Directory of Open Access Journals (Sweden)

    Hong Chen

    2011-11-01

    Full Text Available In the title compound, C30H32N2O7·CH4O, the tetrahydrofuran ring and the six-membered ring fused to it both display envelope conformations, with the ring C atom opposite the carbonyl group and the adjacent bridgehead C atom as the flaps, respectively. In the crystal structure, intermolecular O—H...O hydrogen bonds link all moieties into ribbons along [010]. Weak intermolecular C—H...O interactions consolidate the crystal packing further.

  20. Stereochemistry and Mechanistic Insight in the [2(k)+2(i)+2(i)] Annulations of Ketenes and Imines.

    Science.gov (United States)

    Yang, Zhanhui; He, Wei; Cheng, Baoxiang; Xu, Jiaxi

    2016-06-03

    The stereochemistry and mechanistic insight in the annulations of one ketene molecule with two imine molecules ([2(k)+2(i)+2(i)] annulation) are studied by using six-membered 3,4-dihydroisoquinoline as an imine probe. A concerted hetero-Diels-Alder cycloaddition mechanism is proposed to explain the stereochemical outcomes. In most cases, the zwitterionic 2-aza-1,3-butadiene-type intermediates, generated from ketenes and imines, undergo endo hetero-Diels-Alder cycloaddition with the second imine molecule. For ketenes with electron-donating substituents, (2,4)-cis-(4,5)-cis-[2(k)+2(i)+2(i)] annuladducts formed stereospecifically, while, for ketenes with electron-accepting substituents, (2,4)-cis-(4,5)-trans-[2(k)+2(i)+2(i)] annuladducts are generated stereospecifically. The [2(k)+2(i)+2(i)] annulations of aryloxyketenes and 3,4-dihydroisoquinoline give stereodivergent products due to the occurrence of the stepwise nucleophilic annulation. However, in the [2(k)+2(i)+2(i)] annulations of seven-membered cyclic imine dibenzo[b,f][1,4]oxazepine, the zwitterionic aza-butadiene-type intermediates exclusively undergo exo hetero-Diels-Alder cycloadditions with another molecule of imine to yield (2,4)-trans-(4,5)-trans-[2(k)+2(i)+2(i)] annuladducts stereospecifically, regardless of the ketene substituents. The mechanistic model not only discloses the nature of the [2(k)+2(i)+2(i)] annulations, but also can be used to explain and predict the stereochemistry of the [2(k)+2(i)+2(i)] annuladducts from different ketenes and imines.

  1. K2P2.1 (TREK-1)–activator complexes reveal a cryptic selectivity filter binding site

    Energy Technology Data Exchange (ETDEWEB)

    Lolicato, Marco; Arrigoni, Cristina; Mori, Takahiro; Sekioka, Yoko; Bryant, Clifford; Clark, Kimberly A.; Minor, Jr , Daniel L. (Ono); (UCSF)

    2017-07-10

    Polymodal thermo- and mechanosensitive two-pore domain potassium (K2P) channels of the TREK1 subfamily generate ‘leak’ currents that regulate neuronal excitability, respond to lipids, temperature and mechanical stretch, and influence pain, temperature perception and anaesthetic responses1, 2, 3. These dimeric voltage-gated ion channel (VGIC) superfamily members have a unique topology comprising two pore-forming regions per subunit4, 5, 6. In contrast to other potassium channels, K2P channels use a selectivity filter ‘C-type’ gate7, 8, 9, 10 as the principal gating site. Despite recent advances3, 11, 12, poor pharmacological profiles of K2P channels limit mechanistic and biological studies. Here we describe a class of small-molecule TREK activators that directly stimulate the C-type gate by acting as molecular wedges that restrict interdomain interface movement behind the selectivity filter. Structures of K2P2.1 (also known as TREK-1) alone and with two selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activators—an N-aryl-sulfonamide, ML335, and a thiophene-carboxamide, ML402—define a cryptic binding pocket unlike other ion channel small-molecule binding sites and, together with functional studies, identify a cation–π interaction that controls selectivity. Together, our data reveal a druggable K2P site that stabilizes the C-type gate ‘leak mode’ and provide direct evidence for K2P selectivity filter gating.

  2. 番茄灰霉病拮抗菌K2的筛选及鉴定%The Screening and Identification of an Antagonism Strain K 2 of Botrytis cinerea

    Institute of Scientific and Technical Information of China (English)

    丁永辉; 陈玲英; 梅丽娟

    2015-01-01

    One antagonism strain of bacteria called K-2 is separated from soil,which can strongly antagonize Botrytis cinerea .After 5-days’culture plate confrontation experiment be-tween K-2 and Botrytis cinerea JY1-4,obvious bacteriostatic belt appears with the bacteriosta-tios ratio of 66.1 9%,and 15 days later stable antibacterial effect can still remains.Fermentation liquor of K-2 has significant inhibitory effect on spore germination of Botrytis cinerea JY1-4 with the bacteriostatios ratio of 100%.The mechanism of K-2 against germs performs that it can make hypha deform distorted and restrain bacteria conidium germination.The colonization experiment in soil results shows that in the field of in-situ conditions the antagonist K-2 will re-duce survival rates for the influence of the indigenous microorganisms,but it still has sustained and stable potential of antagonism ability.%从土壤中分离出一株对蕃茄灰霉病菌(Botrytis cinerea )有较强拮抗能力的细菌 K 2。通过平板对峙培养法对其抑菌效果进行测定,结果表明:1)培养5 d 后,K 2菌落周围产生明显的抑菌带,对 Botrytis cinerea 的抑菌率达66.19%,培养15 d 后仍保持稳定的抑菌效果;2)K 2的发酵原液对 Botrytis cinerea 孢子萌发具有显著的抑制作用,抑制率为100%;3)K 2对病菌的作用机制表现为使病菌菌丝畸形、菌丝扭曲、抑制病菌分生孢子的萌发;4)土壤定殖试验表明,拮抗菌 K 2会受到土著微生物的影响降低存活率,但仍具有在土壤中存活并较长时间保持拮抗能力的潜力。

  3. Insights into the mechanism of the capture of CO2 by K2CO3 sorbent: a DFT study.

    Science.gov (United States)

    Liu, Hongyan; Qin, Qiaoyun; Zhang, Riguang; Ling, Lixia; Wang, Baojun

    2017-09-13

    The adsorption and reactions of CO2 and H2O on both monoclinic and hexagonal crystal K2CO3 were investigated using the density functional theory (DFT) approach. The calculated adsorption energies showed that adsorption of H2O molecules was clearly substantially stronger on the K2CO3 surface than the adsorption of CO2, except on the (001)-1 surface of hexagonal K2CO3, where CO2 is competitively adsorbed with H2O. Carbonation reactions easily occur on pure K2CO3 and involve two parallel paths: one is where adsorbed H2O reacts with molecular CO2 in gas to form the bicarbonate, while the other is where H2O dissociates into OH and H before bicarbonate formation, and then OH reacts with gaseous CO2 to form a bicarbonate. Our results indicate that adding a support or promoter or using a special technique to expose more (001)-1 surfaces in hexagonal K2CO3 may improve the conversion of CO2 to the bicarbonate, which provides a theoretical direction for the experimental preparation of the K2CO3 sorbent to capture CO2.

  4. Spitzer Observations Confirm and Rescue the Habitable-Zone Super-Earth K2-18b for Future Characterization

    CERN Document Server

    Benneke, Björn; Petigura, Erik; Knutson, Heather; Dressing, Courtney; Crossfield, Ian J M; Schlieder, Joshua E; Livingston, John; Beichman, Charles; Christiansen, Jessie; Krick, Jessica; Gorjian, Varoujan; Howard, Andrew W; Sinukoff, Evan; Ciardi, David R; Akeson, Rachel L

    2016-01-01

    The recent detections of two transit events attributed to the super-Earth candidate K2-18b have provided the unprecedented prospect of spectroscopically studying a habitable-zone planet outside the Solar System. Orbiting a nearby M2.5 dwarf and receiving virtually the same stellar insolation as Earth, K2-18b would be a prime candidate for the first detailed atmospheric characterization of a habitable-zone exoplanet using HST and JWST. Here, we report the detection of a third transit of K2-18b near the predicted transit time using the Spitzer Space Telescope. The Spitzer detection demonstrates the periodic nature of the two transit events discovered by K2, confirming that K2-18 is indeed orbited by a super-Earth in a 33-day orbit and ruling out the alternative scenario of two similarly-sized, long-period planets transiting only once within the 75-day K2 observation. We also find, however, that the transit event detected by Spitzer occurred 1.85 hours (7-sigma) before the predicted transit time. Our joint analy...

  5. Modeling aerosol surface chemistry and gas-particle interaction kinetics with K2-SURF: PAH oxidation

    Science.gov (United States)

    Shiraiwa, M.; Garland, R.; Pöschl, U.

    2009-04-01

    Atmospheric aerosols are ubiquitous in the atmosphere. They have the ability to impact cloud properties, radiative balance and provide surfaces for heterogeneous reactions. The uptake of gaseous species on aerosol surfaces impacts both the aerosol particles and the atmospheric budget of trace gases. These subsequent changes to the aerosol can in turn impact the aerosol chemical and physical properties. However, this uptake, as well as the impact on the aerosol, is not fully understood. This uncertainty is due not only to limited measurement data, but also a dearth of comprehensive and applicable modeling formalizations used for the analysis, interpretation and description of these heterogeneous processes. Without a common model framework, comparing and extrapolating experimental data is difficult. In this study, a novel kinetic surface model (K2-SURF) [Ammann & Pöschl, 2007; Pöschl et al., 2007] was used to describe the oxidation of a variety of polycyclic aromatic hydrocarbons (PAHs). Integrated into this consistent and universally applicable kinetic and thermodynamic process model are the concepts, terminologies and mathematical formalizations essential to the description of atmospherically relevant physicochemical processes involving organic and mixed organic-inorganic aerosols. Within this process model framework, a detailed master mechanism, simplified mechanism and parameterizations of atmospheric aerosol chemistry are being developed and integrated in analogy to existing mechanisms and parameterizations of atmospheric gas-phase chemistry. One of the key aspects to this model is the defining of a clear distinction between various layers of the particle and surrounding gas phase. The processes occurring at each layer can be fully described using known fluxes and kinetic parameters. Using this system there is a clear separation of gas phase, gas-surface and surface bulk transport and reactions. The partitioning of compounds can be calculated using the flux

  6. 新生儿巨细胞病毒感染的胞外体二肽基肽酶Ⅳ及血清中白细胞介素-6,-8水平的研究%Levels of Dipeptidyl Peptidase Ⅳ and Interleukin-6,-8 in Neonates of Cytomegalovirus Infection

    Institute of Scientific and Technical Information of China (English)

    李晓莺; 卢宪梅; 阎贝贝; 胡晓燕

    2012-01-01

    Objective To study the levels of dipeptidyl peptidase Ⅳ (DPPⅣ)of exosome(EXO) and interleukin(IL)-6,-8 in serum of neonates with cytomegalovirus(CMV) infection,to investigate the influence of CMV on neonates' immune function,and the roles of DPPⅣ,and IL-6,-8 in serum which played in the process of CMV infection.Methods From January 2008 to December 2010,a total of 53 neonates with CMV infection were collected as CMV group,meanwhile the other 52 non-CMV infection neonates were recruited as control group.By ELASA method to detect the levels of EXO-DPPⅣ and IL-6,-8 in serum,then analysis the differences between two groups.Informed consent was obtained from the parents of each participating neonate.There had no significant difference between two groups among gender,age,gestational age etc.(P>0.05).Results The levels of EXO-DPPⅣ,and IL-6,-8 in serum in CMV group were much higher than those in control group,and had significance difference (P<0.05).Conclusions CMV can break normal immune balance,leading abnormality of enzymes and cytokine.There is close correlation between inflammatory reaction,DPPⅣ,and IL-6,-8.%目的 探讨巨细胞病毒(CMV)感染对新生儿免疫功能的影响及胞外体(EXO)二肽基肽酶Ⅳ(DPPⅣ,CD26)及血清白细胞介素(IL)-6,-8水平在CMV感染发生发展过程中的作用.方法 选择2008年1月至2010年12月山东大学齐鲁医院儿科收治的53例CMV感染新生儿为研究对象,纳入CMV组,选择同期入院的42例非CMV感染新生儿(CMV IgM呈阴性,血、尿中CMV-DNA< 103拷贝/mL)纳入对照组.采用ELASA法检测EXO-DPPⅣ活性及血清IL-6,-8水平,并进行相关统计学分析(本研究遵循的程序符合山东大学齐鲁医院人体试验委员会制定的伦理学标准,得到该委员会批准,分组征得受试对象监护人的知情同意,并与其签署临床研究知情同意书).两组新生儿的性别、年龄及胎龄等比较,差异无统计学意义(P>0.05).结果 CMV组

  7. Peripheral bone mineral density and different intensities of physical activity in children 6-8 years old: the Copenhagen School Child Intervention study

    DEFF Research Database (Denmark)

    Hasselstrøm, H; Karlsson, K M; Hansen, S E

    2007-01-01

    This study aimed to evaluate the association between objectively measured habitual physical activity and calcaneal and forearm bone mineral density (BMD, g/cm(2)), one mechanically more loaded and one less loaded skeletal region, in children aged 6-8 years. BMD was measured in 297 boys and 265...... girls by peripheral dual-energy X-ray absorptiometry in the forearm and calcaneus. An accelerometer registered the level of physical activity during 4 days (2 weekdays and the weekend). Weight, height, and skinfold thickness were measured. In order to establish thresholds (count . min(-1)) for bone......-stimulating physical activity, we evaluated different definitions of vigorous physical activity. The boys had 3.2% higher distal forearm bone mineral content (BMC, P physical activity and spent 14.6-19.0% more...

  8. Anti-Inflammatory Effects of 6,8-Diprenyl-7,4'-dihydroxyflavanone from Sophora tonkinensis on Lipopolysaccharide-Stimulated RAW 264.7 Cells.

    Science.gov (United States)

    Chae, Hee-Sung; Yoo, Hunseung; Kim, Young-Mi; Choi, Young Hee; Lee, Chang Hoon; Chin, Young-Won

    2016-08-11

    The anti-inflammatory effects and molecular mechanism of 6,8-diprenyl-7,4'-dihydroxyflavanone (DDF), one of the flavanones found in Sophora tonkinensis, were assessed in vitro through macrophage-mediated inflammation in the present study. The anti-inflammatory effects of DDF were not previously reported. DDF inhibited the production of nitric oxide and the expression of tumor necrosis factor α, interleukin-1β, and interleukin-6. Furthermore, the activation of nuclear factor-κB (NF-κB) and extracellular signal-regulated kinases (ERKs) in lipopolysaccharide-stimulated macrophages was suppressed by treatment with DDF. Therefore, DDF demonstrated potentially anti-inflammatory effects via the blockade of NF-κB and ERK activation in macrophages.

  9. Contribution of higher multiplicity collisions to elastic p{sup 6,8}He and p{sup 8,9}Li scattering within Glauber theory

    Energy Technology Data Exchange (ETDEWEB)

    Ibraeva, E. T., E-mail: ibraeva.elena@gmail.com [National Nuclear Center of Republic of Kazakhstan, Institute of Nuclear Physics (Kazakhstan); Imambekov, O. [Al-Farabi Kazakh National University (Kazakhstan)

    2015-07-15

    Differential cross sections for elastic p{sup 6,8}He and p{sup 8,9}Li scattering at energies between 60 and 70 MeV per nucleon and at the energy of 700 MeV per nucleon were calculated. The calculations in question were performed with the wave functions found on the basis of the α–n–n (for {sup 6}He), α–t–n (for {sup 8}Li), and α–t–2n (for {sup 9}Li) three-body models and with the density from the large-scale shell model for the {sup 8}He nucleus. The respective matrix elements were derived either upon taking fully into account the multiple-scattering operator or in the optical-limit approximation. A comparison of the results of the precise and approximate calculations made it possible to estimate reliably the contribution of higher multiplicity collisions to the differential cross sections.

  10. Identification of a putative methylenetetrahydrofolate reductase by sequence analysis of a 6.8 kb DNA fragment of yeast chromosome VII.

    Science.gov (United States)

    Tizon, B; Rodríguez-Torres, M; Rodríguez-Belmonte, E; Cadahia, J L; Cerdan, E

    1996-09-01

    We report the sequence analysis of a 6.8 kb DNA fragment from Saccharomyces cerevisiae chromosome VII. This sequence contains five open reading frames (ORFs) greater than 100 amino acids. There is also an incomplete ORF flanking one of the extremes, G2868, which is the 3' end of the SCS3 gene (Hosaka et al., 1994). The translated sequence of ORF G2882 shows similarity to the human methylenetetrahydrofolate reductase (Goyette et al., 1994). ORF G2889 shows no significant homologies with the sequences compiled in databases. ORF G2893 corresponds to the gene SUP44, coding for the yeast ribosomal protein S4 (All-Robin et al., 1990). G2873 and G2896 are internal ORFs.

  11. 介孔分子筛K2O/SBA-15催化酯化反应的研究%Esterification Catalyzed by Mesoporous Sieve K2 O/SBA-15

    Institute of Scientific and Technical Information of China (English)

    崔晓燕; 沈健; 刘琤; 沈思维

    2011-01-01

    以介孔分子筛SBA-15为载体,负载KNO3后经过煅烧,制得K2O/SBA-15固体碱催化剂.通过XRD和BET对样品进行了测试分析,并对K2O/SBA-15催化合成油酸甲酯的酯化反应进行了研究.试验结果表明:当K2O负载量为2%,n(醇)∶n(酸)2∶1,反应温度180℃,反应时间4 h,催化剂用量为原料质量的5.0%时,酯化率最大达到83.61%,并且K2O/SBA-15催化剂重复使用多次仍具有较好的催化效果.%Solid base catalyst K2O/SBA-15 was prepared by loading potassium nitrate on mesoporous sieve SBA-15 and then was calcined. The samples were characterized by XRD and BET and used as catalyst in the synthesis of methyl oleate. The experimental results showed that when the loaded amount of K2O was 2% , molar ratio of methanol/oleic acid was 2:1 ,reaction temperature was 180 ℃ ,reaction time was 4 h and the ratio of catalyst to raw material was 5% ( weight ratio), the esterification rate was 83.61%. The results also showed that K2O/SBA-15had a good catalytic effect after resued.

  12. Joint inversion of teleseismic body-waves and geodetic data for the Mw6.8 aftershock of the Balochistan earthquake with refined epicenter location

    Science.gov (United States)

    Wei, S.; Wang, T.; Jonsson, S.; Avouac, J. P.; Helmberger, D. V.

    2014-12-01

    Aftershocks of the 2013 Balochistan earthquake are mainly concentrated along the northeastern end of the mainshock rupture despite of much larger coseismic slip to the southwest. The largest event among them is an Mw6.8 earthquake which occurred three days after the mainshock. A kinematic slip model of the mainshock was obtained by joint inversion of the teleseismic body-waves and horizontal static deformation field derived from remote sensing optical and SAR data, which is composed of seven fault segments with gradually changing strikes and dips [Avouac et al., 2014]. The remote sensing data provide well constraints on the fault geometry and spatial distribution of slip but no timing information. Meanwhile, the initiation of the teleseismic waveform is very sensitive to fault geometry of the epicenter segment (strike and dip) and spatial slip distribution but much less sensitive to the absolute location of the epicenter. The combination of the two data sets allows a much better determination of the absolute epicenter location, which is about 25km to the southwest of the NEIC epicenter location. The well located mainshock epicenter is used to establish path calibrations for teleseismic P-waves, which are essential for relocating the Mw6.8 aftershock. Our grid search shows that the refined epicenter is located right at the northeastern end of the mainshock rupture. This is confirmed by the SAR offsets calculated from images acquired after the mainshock. The azimuth and range offsets display a discontinuity across the rupture trace of the mainshock. Teleseismic only and static only, as well as joint inversions all indicate that the aftershock ruptured an asperity with 25km along strike and range from 8km to 20km in depth. The earthquake was originated in a positive Coulomb stress change regime due to the mainshock and has complementary slip distribution to the mainshock rupture at the northeastern end, suggesting that the entire seismic generic zone in the crust was

  13. Cell reproductive patterns in the green alga Pseudokirchneriella subcapitata (=Selenastrum capricornutum) and their variations under exposure to the typical toxicants potassium dichromate and 3,5-DCP

    Science.gov (United States)

    Yamagishi, Takahiro; Yamaguchi, Haruyo; Suzuki, Shigekatsu; Horie, Yoshifumi; Tatarazako, Norihisa

    2017-01-01

    Pseudokirchneriella subcapitata is a sickle-shaped freshwater green microalga that is normally found in unicellular form. Currently, it is the best known and most frequently used species of ecotoxicological bioindicator because of its high growth rate and sensitivity to toxicants. However, despite this organism’s, our knowledge of its cell biology—for example, the patterns of nuclear and cytoplasmic division in the mitotic stage—is limited. Although it has been reported that P. subcapitata proliferates by popularity forming four daughter cells (autospores) through multiple fission after two nuclear divisions, here, we report two additional reproductive patterns by which two autospores are formed by binary fission (“two-autospore type”) and eight autospores are formed by multiple fission (“eight-autospore type”). Moreover, we found that cell reproductive patterns differed markedly with the culture conditions or with exposure to either of two typical toxicants, potassium dichromate (K2Cr2O7) and 3,5-dichlorophenol (3,5-DCP). The eight-autospore type occurred at the highest frequency in the early phase of culture, but it disappeared under 3,5-DCP at 2.0 mg/L. Under 0.3 mg/L K2CrO7 (Cr(VI)) the eight-autospore type took substantially longer to appear than in control culture. The two-autospore type occurred only in the late phase of culture. To our knowledge, this is the first detailed evaluation of the reproductive patterns of P. subcapitata, which changed dramatically in the presence of toxicants. These findings suggest that observation of the reproductive patterns of P. subcapitata will help to elucidate different cell reactions to toxicants. PMID:28152022

  14. EPIC201702477b: A Long Period Transiting Brown Dwarf from K2

    CERN Document Server

    Bayliss, D; Santerne, A; Dragomir, D; Zhou, G; Shporer, A; Colón, K D; Almenara, J; Armstrong, D J; Barrado, D; Barros, S C C; Bento, J; Boisse, I; Bouchy, F; Brown, D J A; Brown, T; Cameron, A; Cochran, W D; Demangeon, O; Deleuil, M; Díaz, R F; Fulton, B; Horne, K; Hébrard, G; Lillo-Box, J; Lovis, C; Mawet, D; Ngo, H; Osborn, H; Palle, E; Petigura, E; Pollacco, D; Santos, N; Sefako, R; Siverd, R; Sousa, S G; Tsantaki, M

    2016-01-01

    We report the discovery of EPIC201702477b, a transiting brown dwarf in a long period (40.73691 +/- 0.00037 day) and eccentric (e=0.2281 +/- 0.0026) orbit. This system was initially reported as a planetary candidate based on two transit events seen in K2 Campaign 1 photometry and later validated as an exoplanet. We confirm the transit and refine the ephemeris with two subsequent ground-based detections of the transit using the LCOGT 1m telescope network. We rule out any transit timing variations above the level of 30s. Using high precision radial velocity measurements from HARPS and SOPHIE we identify the transiting companion as a brown dwarf with a mass, radius, and bulk density of 66.9 +/- 1.7 M$_J$, 0.757 +/- 0.065 R$_J$, and 191+/-51 g.cm$^{-3}$ respectively. EPIC201702477b is the smallest radius brown dwarf yet discovered, with a mass just below the H-burning limit. It has the highest density of any planet, substellar mass object or main-sequence star discovered so far. We find evidence in the set of know...

  15. Rotation in the Pleiades with K2: I. Data and First Results

    CERN Document Server

    Rebull, L M; Bouvier, J; Cody, A M; Hillenbrand, L A; Soderblom, D; Valenti, J; Barrado, D; Bouy, H; Ciardi, D; Pinsonneault, M; Stassun, K; Micela, G; Aigrain, S; Vrba, F; Somers, G; Christiansen, J; Gillen, E; Cameron, A Collier

    2016-01-01

    Young (125 Myr), populous ($>$1000 members), and relatively nearby, the Pleiades has provided an anchor for stellar angular momentum models for both younger and older stars. We used K2 to explore the distribution of rotation periods in the Pleiades. With more than 500 new periods for Pleiades members, we are vastly expanding the number of Pleiads with periods, particularly at the low mass end. About 92\\% of the members in our sample have at least one measured spot-modulated rotation period. For the $\\sim$8\\% of the members without periods, non-astrophysical effects often dominate (saturation, etc.), such that periodic signals might have been detectable, all other things being equal. We now have an unusually complete view of the rotation distribution in the Pleiades. The relationship between $P$ and $(V-K_{\\rm s})_0$ follows the overall trends found in other Pleiades studies. There is a slowly rotating sequence for $1.1\\lesssim(V-K_{\\rm s})_0\\lesssim 3.7$, and a primarily rapidly rotating population for $(V-K_...

  16. Expectations on $B\\to (K^*_{0}(1430),K^*_{2}(1430))\\phi$ decays

    CERN Document Server

    Chen, C H; Chen, Chuan-Hung; Geng, Chao-Qiang

    2007-01-01

    As the annihilation contributions play important roles in solving the puzzle of the small longitudinal polarizations in $B\\to K^* \\phi$ decays, we examine the similar effects in the decays of $B\\to K^*_{0,2}(1430) \\phi$. For the calculations on the annihilated contributions, we adopt that the form factors in $B\\to K^{(*)} \\phi$ decays are parameters determined by the observed branching ratios (BRs), polarization fractions (PFs) and relative angles in experiments and we connect the parameters between $B\\to K^*_{0(2)} \\phi$ and $B\\to K^{(*)}\\phi$ by the ansatz of correlating $\\la K^*_n(1430) \\phi| (V-A)_{\\mu}|0\\ra$ to $\\la K^{(*)} \\phi| (V-A)_{\\mu}|0\\ra$. We find that the BR of $B_d\\to K^{*0}_{0}(1430) \\phi$ is $(3.69 \\pm 0.47)\\times 10^{-6}$. By using the transition form factors of $B\\to K^*_2(1430)$ in the light-front quark model (LFQM) and the 2nd version of Isgur-Scora-Grinstein-Wise (ISGW2), we show that BR of $B_d\\to K^{*0}_{2}(1430)\\phi$ is a broad allowed value and $(1.70\\pm0.80)\\times 10^{-6}$, respect...

  17. Final report on APMP.M.FF-K2 bilateral comparison: Hydrocarbon liquid flow

    Science.gov (United States)

    Chen, I.-Cheng; Su, Chun-Min; Yang, Cheng-Tsair; Thai, Nguyen Hong

    2012-01-01

    This bilateral comparison was carried out in the field of liquid hydrocarbon flow following the Guidelines for CIPM Key Comparisons. This APMP.M.FF-K2 comparison involved two laboratories: Center for Measurement Standards (CMS, Chinese Taipei) and Vietnam Measurement Institute (VMI), which are both national standard calibration laboratories. The bilateral comparison was conducted using light liquid hydrocarbon across a flow range of 5 L s-1 to 30 L s-1. A Kral positive displacement meter served as the transfer standard. The Strouhal number and Reynolds number served as the key parameters for expressing the laboratories' measurements of volume and flowrate. The En value of the VMI test results with reference to CMS was 0.28. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  18. Nonlinear magneto-optical resonances for systems with J~100 observed in K2 molecules

    CERN Document Server

    Auzinsh, M; Fescenko, I; Kalvans, L; Tamanis, M

    2012-01-01

    We present the results of an experimental as well as theoretical study of nonlinear magneto-optical resonances in diatomic potassium molecules in the electronic ground state with large values of the angular momentum quantum number J~100. At zero magnetic field, the absorption transitions are suppressed because of population trapping in the ground state due to Zeeman coherences between magnetic sublevels of this state along with depopulation pumping. The destruction of such coherences in an external magnetic field was used to study the resonances in this work. K2 molecules were formed in a glass cell filled with potassium metal at a temperature above 150^{\\circ}C. The cell was placed in an oven and was located in a homogeneous magnetic field B, which was scanned from zero to 0.7 T. Q-type and R-type transitions were excited with a tunable, single-mode diode laser at a wavelength of 661 nm. Well pronounced nonlinear Hanle effect signals were observed in the intensities of the linearly polarized components of th...

  19. Physical characteristics of Cenaturs and trans-Neptunian objects from combined K2 and Herschel observations

    Science.gov (United States)

    Kiss, Csaba; Pal, Andras; Farkas Anikó, Takácsné; Marciniak, Anna; Mueller, Thomas G.; Kiss, Laszlo L.; Szabo, Gyula M.; Szabo, Robert; Sarneczky, Krisztian; Molnar, Laszlo

    2016-10-01

    Here we present the results of a comprehensive rotational and radiometric analysis of trans-Neptunian objects (TNOs) observed with the Kepler Space Observatory in the K2 mission and earlier with the Herschel Space Observatory at infrared wavelengths. The combined optical light curves and thermal emission data revealed a slow rotation rate of ~45h for the large Kuiper belt object 2007 OR10, and we obtained a diameter of ~1535 km that makes 2007 OR10 the third largest TNO after Pluto and Eris. The large size also implies a relatively dark surface, unusual among the dwarf planets in the outer Solar system. We also present rotational curves, physical characteristics and shape models for the Centaur 2002 KY14, for three Classical Kuiper belt objects, 1998 SN165, 2001 QT322 and 2003 QW90, and for two resonant TNOs, 2001 YH140 and 2005 RS43. In the case of 2003 QW90, 2001 YH140 and 2005 RS43 our results are based on so far unpublished thermal emission data from Herschel and Spitzer observations.

  20. The heart of the swarm: K2 photometry and rotational characteristics of 56 Jovian Trojan asteroids

    Science.gov (United States)

    Szabó, Gy. M.; Pál, A.; Kiss, Cs.; Kiss, L. L.; Molnár, L.; Hanyecz, O.; Plachy, E.; Sárneczky, K.; Szabó, R.

    2017-02-01

    We present fully covered phased light curves for 56 Jovian Trojan asteroids as observed by the K2 mission of the Kepler space telescope. This set of objects has been monitored during Campaign 6 and represents a nearly unbiased subsample of the population of small solar system bodies. We derived precise periods and amplitudes for all Trojans, and found their distributions to be compatible with the previous statistics. We point out, however, that ground-based rotation periods are often unreliable above 20 h, and we find an overabundance of rotation periods above 60 h compared with other minor planet populations. From amplitude analysis we derive a rate of binarity of 20 ± 5%. Our spin rate distribution confirms the previously obtained spin barrier of 5 h and the corresponding 0.5 g cm-3 cometary-like density limit, also suggesting a high internal porosity for Jovian Trojans. One of our targets, asteroid 65227 exhibits a double rotation period, which can either be due to binarity or the outcome of a recent collision.

  1. Doppler shifts on the spin period of the intermediate polar FO Aqr with K2

    CERN Document Server

    Scaringi, S; Maccarone, T J

    2016-01-01

    We analyse the K2 short cadence data of the intermediate polar FO Aqr and provide accurate and updated orbital and spin periodicities. We additionally find small spin period changes as a function of orbital phase of ~0.02 seconds translating to velocities of ~ a few km/s. The obtained orbital-folded velocity profile displays two clear maxima and minima, and cannot be explained by the radial velocity of the orbiting white dwarf. Instead we propose that the observed velocities are the sum of the radial velocities of both the white dwarf and of the stellar surface facing the white dwarf which reprocesses the WD spin pulses. This combination can explain the observed low velocities in FO Aqr. However asymmetries in the orbital configuration are required to explain the double peaked velocity profile. One possible scenario would invoke binary eccentricity. We thus developed a simple binary model to explain and fit our observations, and find a small binary eccentricity of e=0.03. Although small, persistent eccentrici...

  2. An independent discovery of two hot Jupiters from the K2 mission

    CERN Document Server

    Brahm, Rafael; Espinoza, Néstor; Jordán, Andrés; Rabus, Markus; Rojas, Felipe; Jenkins, James S; Cortés, Cristián; Drass, Holger; Pantoja, Blake; Soto, Maritza G; Vučković, Maja

    2016-01-01

    We report the discovery of two hot Jupiters using photometry from Campaigns 4 and 5 of the two-wheeled Kepler (K2) mission. EPIC210957318b has a mass of $ 0.65 \\pm 0.14 M_J$, a radius of $1.070 \\pm 0.018 R_J$ and transits its G dwarf ($T_{eff} = 5675 \\pm 50$ K), slightly metal rich ([Fe/H]$=+0.06\\pm0.04$ dex) host star in a 4.1 days circular orbit. EPIC212110888b has a mass of $ 1.63 \\pm 0.12 M_J$, a radius of $1.38 \\pm 0.014 R_J$ and has an orbital period of 3.0 days in which it orbits a late F dwarf ($T_{eff} = 6149 \\pm 55$ K) solar metallicity star. Both planets were validated probabilistically and confirmed via precision radial velocity (RV) measurements. They have physical and orbital properties similar to the ones of the already uncovered population of hot Jupiters and are well-suited candidates for further orbital and atmospheric characterization via detailed follow-up observations.

  3. K2 Ultracool Dwarfs Survey I: Photometry of an L Dwarf Superflare

    CERN Document Server

    Gizis, John E; Schmidt, Sarah J; Williams, Peter K G; Burgasser, Adam J

    2016-01-01

    We report on K2 Campaign 8 measurements of a huge white light flare on the L1 dwarf SDSSp J005406.55-003101.8 (EPIC 220186653). The source is a typical L1 dwarf at a distance of $\\sim50$ pc, probably an old hydrogen-burning star rather than a young brown dwarf. In the long (30-minute) cadence photometry, the flare peak is 21 times the flux of the stellar photosphere in the broad optical Kepler filter, which we estimate corresponds to $\\Delta V \\approx -7.1$. The total equivalent duration of the flare is 15.4 hr. We estimate the total bolometric energy of the flare was $4 \\times 10^{33}$ erg, more powerful that the previously reported Kepler white light flares for the L1 dwarf WISEP J190648.47+401106.8, but weaker than the $\\Delta V = -11$ L0 dwarf superflare ASASSN-16ae. The initial (impulsive) cooling phase is too rapid to resolve with our 30-minute cadence data, but after one hour the gradual cooling phase has an exponential time constant of 1.8 hours. We use template fitting to estimate that the full-time-...

  4. Na+-K+-2Cl- cotransporter type 2 trafficking and activity: the role of interacting proteins.

    Science.gov (United States)

    Carmosino, Monica; Procino, Giuseppe; Svelto, Maria

    2012-04-01

    The central role of Na+-K+-2Cl- cotransporter type 2 (NKCC2) in vectorial transepithelial salt reabsorption in thick ascending limb cells from Henle's loop in the kidney is evidenced by the effects of loop diuretics, the pharmacological inhibitors of NKCC2, that are amongst the most powerful antihypertensive drugs available to date. Moreover, genetic mutations of the NKCC2 encoding gene resulting in impaired apical targeting and function of NKCC2 transporter give rise to a pathological phenotype known as type I Bartter syndrome, characterised by a severe volume depletion, hypokalaemia and metabolic alkalosis with high prenatal mortality. On the contrary, excessive NKCC2 activity has been linked with inherited hypertension in humans and in rodent models. Interestingly, in animal models of hypertension, NKCC2 upregulation is achieved by post-translational mechanisms underlining the need to analyse the molecular mechanisms involved in the regulation of NKCC2 trafficking and activity to gain insights in the pathogenesis of hypertension. Copyright © 2012 Soçiété Francaise des Microscopies and Société de Biologie Cellulaire de France.

  5. Production of menaquinone (vitamin K2)-7 by Bacillus subtilis.

    Science.gov (United States)

    Sato, T; Yamada, Y; Ohtani, Y; Mitsui, N; Murasawa, H; Araki, S

    2001-01-01

    Menaquinone-7 (MK-7) is a highly bioactive homologue of vitamin K. We obtained a diphenylamine-resistant mutant strain D200-41 from Bacillus subtilis strain MH-1 which was isolated from fermented soybeans, natto. The mutant strain exhibited decreased production of MK-6. Using strain D200-41, efficient production of MK-7 was achieved. We found that, compared with an agitated and aerated culture, production of MK-7 was increased by static culture. The sporulation of the cells progressed more slowly in a static culture than in an agitated culture. The maximum concentration of MK reached about 60 mg/l in a medium containing 10% soybean extract, 5% glycerol, 0.5% yeast extract and 0.05% K2HPO4 (pH 7.3) when D200-41 cells as well as MH-1 cells were statically cultured at 45 degrees C for 5 d after being cultured with shaking at 37 degrees C for 1 d.

  6. Effect of vitamin K2 on three-dimensional trabecular microarchitecture in ovariectomized rats.

    Science.gov (United States)

    Mawatari, T; Miura, H; Higaki, H; Moro-Oka, T; Kurata, K; Murakami, T; Iwamoto, Y

    2000-09-01

    Menatetrenone, a vitamin K2 with four isoprene units, has been reported to improve osteoporotic bone loss. The purpose of this investigation was to clarify the effect of menatetrenone on the three-dimensional (3D) trabecular microarchitecture in ovariectomized (OVX) rats by using microcomputed tomography (MCT). Forty-two 13-week-old female rats were used and divided into four groups: the OVX (OVX + MK-4) group treated with menatetrenone, the (OVX untreated) group, the sham-operated (Sham + MK-4) group treated with menatetrenone, and the sham-operated group not treated with menatetrenone (Sham untreated) group. OVX rats were fed a calcium-deficient diet. Menatetrenone treatment was begun just after the ovariectomy, and the mean menatetrenone oral intake over the 8-week period was adjusted to 30 mg/kg BW per day. The proximal metaphyseal region of the right tibia was evaluated by dual X-ray absorptiometry (DXA) and MCT. A parametric analysis of the reconstructed trabecular volume was carried out using bone volume fractions, the fractal dimension calculated by the 3D box-counting method, and the connectivity density as determined by topological analysis. Menatetrenone significantly increased the trabecular bone volume, fractal dimension, and connectivity in the OVX + MK-4 group compared with the OVX-untreated group (p ovariectomy. Despite this apparent protection, it remains unknown whether it is possible to reestablish trabecular connectivity if therapeutic intervention occurs after the trabecular connectivity has been lost.

  7. Osmoregulation Requires Brain Expression of the Renal Na-K-2Cl Cotransporter NKCC2

    Science.gov (United States)

    Konopacka, Agnieszka; Qiu, Jing; Yao, Song T.; Greenwood, Michael P.; Greenwood, Mingkwan; Lancaster, Thomas; Inoue, Wataru; de Souza Mecawi, Andre; Vechiato, Fernanda M.V.; de Lima, Juliana B.M.; Coletti, Ricardo; Hoe, See Ziau; Martin, Andrew; Lee, Justina; Joseph, Marina; Hindmarch, Charles; Paton, Julian; Antunes-Rodrigues, Jose; Bains, Jaideep

    2015-01-01

    The Na-K-2Cl cotransporter 2 (NKCC2) was thought to be kidney specific. Here we show expression in the brain hypothalamo-neurohypophyseal system (HNS), wherein upregulation follows osmotic stress. The HNS controls osmotic stability through the synthesis and release of the neuropeptide hormone, arginine vasopressin (AVP). AVP travels through the bloodstream to the kidney, where it promotes water conservation. Knockdown of HNS NKCC2 elicited profound effects on fluid balance following ingestion of a high-salt solution—rats produced significantly more urine, concomitant with increases in fluid intake and plasma osmolality. Since NKCC2 is the molecular target of the loop diuretics bumetanide and furosemide, we asked about their effects on HNS function following disturbed water balance. Dehydration-evoked GABA-mediated excitation of AVP neurons was reversed by bumetanide, and furosemide blocked AVP release, both in vivo and in hypothalamic explants. Thus, NKCC2-dependent brain mechanisms that regulate osmotic stability are disrupted by loop diuretics in rats. PMID:25834041

  8. That's How We Roll: The NASA K2 Mission Science Products and Their Performance Metrics

    CERN Document Server

    Van Cleve, Jeffrey E; Smith, Jeffrey C; Clarke, Bruce D; Thompson, Susan E; Bryson, Stephen T; Lund, Mikkel N; Handberg, Rasmus; Chaplin, William J

    2015-01-01

    NASA's exoplanet Discovery mission Kepler was reconstituted as the K2 mission a year after the failure of the 2nd of Kepler's 4 reaction wheels in May 2013. The new spacecraft pointing method now gives typical roll motion of 1.0 pixels peak-to-peak over 6 hours at the edges of the field, two orders of magnitude greater than for Kepler. Despite these roll errors, the flight system and its modified science data processing pipeline restores much of the photometric precision of the primary mission while viewing a wide variety of targets, thus turning adversity into diversity. We define metrics for data compression and pixel budget available in each campaign; the photometric noise on exoplanet transit and stellar activity time scales; residual correlations in corrected long cadence light curves; and the protection of test sinusoidal signals from overfitting in the systematic error removal process. We find that data compression and noise both increase linearly with radial distance from the center of the field of vi...

  9. New Pleiades Eclipsing Binaries and a Hyades Transiting System Identified by K2

    CERN Document Server

    David, Trevor J; Hillenbrand, Lynne A; Stassun, Keivan G; Stauffer, John; Rebull, Luisa M; Cody, Ann Marie; Isaacson, Howard; Howard, Andrew W; Aigrain, Suzanne

    2016-01-01

    We present the discovery in Kepler's $K2$ mission observations and our follow-up radial velocity observations from Keck/HIRES for four eclipsing binary (EB) star systems in the young benchmark Pleiades cluster. Based on our modeling results, we announce two new low mass ($M_{tot} < 0.6 M_\\odot$) EBs among Pleiades members (HCG 76 and MHO 9) and we report on two previously known Pleiades binaries that are also found to be EB systems (HII 2407 and HD 23642). We measured the masses of the binary HCG 76 to $\\lesssim$2.5% precision, and the radii to $\\lesssim$4.5% precision, which together with the precise effective temperatures yield an independent Pleiades distance of 132$\\pm$5 pc. We discuss another EB towards the Pleiades that is a possible but unlikely Pleiades cluster member (AK II 465). The two new confirmed Pleiades systems extend the mass range of Pleiades EB components to 0.2-2 $M_\\odot$. Our initial measurements of the fundamental stellar parameters for the Pleiades EBs are discussed in the context o...

  10. Improved micropropagation and in vitro fruiting of Morus indica L. (K-2 cultivar

    Directory of Open Access Journals (Sweden)

    Gaurab Gogoi

    2017-06-01

    Full Text Available A rapid economically viable micropropagation protocol has been developed in the present work for Morus indica L. (K-2 cultivar utilizing the readily available nodal explants. Explants were established on different plant growth regulators (PGRs either individually or in combinations. MS medium containing 1 mg L−1 Kinetin (Kin showed the best shoot multiplication with 4.8 ± 0.23 cm average shoot length and 6.5 ± 0.03 number of internodes. Regenerated shoots were elongated in MS medium supplemented with 1.5 mg L−1 gibberellic acid (GA3. Elongated shoots cultured in full-strength MS medium supplemented with 1 mg L−1 2,4-dichlorophenoxyacetic acid (2,4-D for one week and then cultured in half-strength MS proved to be more effective in rooting compared to other PGRs in significantly shorter duration. Micropropagated plants transferred to soil fortified with the quarter-strength of MS salts along with humidity regulation process showed 89% survival frequency. In vitro flowering in the regenerated shoots was also observed in the MS medium supplemented with (1.5 mg L−1 Kin and carbon source replaced by commercial sugar cubes. This method can be effectively used for in vitro culture of M. indica in commercial scale owing to its enhanced quality and reduced time frame.

  11. Ultra Short Period Planets in K2 with companions: a double transiting system for EPIC 220674823

    CERN Document Server

    Adams, Elisabeth R; Endl, Michael; Cochran, William D; MacQueen, Phillip J; Duev, Dmitry A; Jensen-Clem, Rebecca; Salama, Maïssa; Ziegler, Carl; Baranec, Christoph; Kulkarni, Shrinivas; Law, Nicholas M; Riddle, Reed

    2016-01-01

    Two transiting planets have been identified orbiting K2 target EPIC 220674823. One object is an ultra-short-period planet with a period of just 0.57 days (13.7 hours), while the other has a period of 13.3 days. Both planets are small, with the former having a radius of R_p1=1.5 R_E and the latter R_p2=2.5 R_E. Follow-up observations, including radial velocity (with uncertainties of 110 m/s) and high-resolution adaptive optics imagery, show no signs of stellar companions. EPIC 220674823 is the twelfth confirmed or validated planetary system in which an ultra-short-period planet (i.e., having an orbital period less than one day) is accompanied by at least one additional planet, suggesting that such systems may be common and must be accounted for in models for the formation and evolution of such extreme systems.

  12. EPIC 201585823, a rare triple-mode RR Lyrae star discovered in K2 mission data

    CERN Document Server

    Kurtz, Donald W; Ebo, Simon J; Moskalik, Pawel; Handberg, Rasmus; Lund, Mikkel N

    2015-01-01

    We have discovered a new, rare triple-mode RR Lyr star, EPIC 201585823, in the Kepler K2 mission Campaign 1 data. This star pulsates primarily in the fundamental and first-overtone radial modes, and, in addition, a third nonradial mode. The ratio of the period of the nonradial mode to that of the first-overtone radial mode, 0.616285, is remarkably similar to that seen in 11 other triple-mode RR Lyr stars, and in 260 RRc stars observed in the Galactic Bulge. This systematic character promises new constraints on RR Lyr star models. We detected subharmonics of the nonradial mode frequency, which are a signature of period doubling of this oscillation; we note that this phenomenon is ubiquitous in RRc and RRd stars observed from space, and from ground with sufficient precision. The nonradial mode and subharmonic frequencies are not constant in frequency or in amplitude. The amplitude spectrum of EPIC 201585823 is dominated by many combination frequencies among the three interacting pulsation mode frequencies. Insp...

  13. ROTATION PERIODS OF YOUNG BROWN DWARFS: K2 SURVEY IN UPPER SCORPIUS

    Energy Technology Data Exchange (ETDEWEB)

    Scholz, Alexander [School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, Fife KY16 9SS (United Kingdom); Kostov, Veselin [Department of Astronomy and Astrophysics, University of Toronto, 50 St. George Street, Toronto, ON M5S 3H4 (Canada); Jayawardhana, Ray [Faculty of Science, York University, 355 Lumbers Building, 4700 Keele Street, Toronto, ON M3J 1P2 (Canada); Mužić, Koraljka, E-mail: as110@st-andrews.ac.uk [Nucleo de Astronomía, Facultad de Ingeniería, Universidad Diego Portales, Av. Ejercito 441, Santiago (Chile)

    2015-08-20

    We report rotational periods for 16 young brown dwarfs in the nearby Upper Scorpius association, based on 72 days of high-cadence, high-precision photometry from the Keplerspace telescope’s K2 mission. The periods range from a few hours to two days (plus one outlier at five days), with a median just above one day, confirming that brown dwarfs, except at the very youngest ages, are fast rotators. Interestingly, four of the slowest rotators in our sample exhibit mid-infrared excess emission from disks; at least two also show signs of disk eclipses and accretion in the light curves. Comparing these new periods with those for two other young clusters and simple angular momentum evolution tracks, we find little or no rotational braking in brown dwarfs between 1–10 Myr, in contrast to low-mass stars. Our findings show that disk braking, while still at work, is inefficient in the substellar regime, thus providing an important constraint on the mass dependence of the braking mechanism.

  14. The heart of the swarm: K2 photometry and rotational characteristics of 56 Jovian Trojan asteroids

    CERN Document Server

    Szabó, Gy M; Kiss, Cs; Kiss, L L; Molnár, L; Hanyecz, O; Plachy, E; Sárneczky, K; Szabó, R

    2016-01-01

    We present fully covered phased light curves for 56 Jovian Trojan asteroids as acquired by the K2 mission of the Kepler space telescope. This set of objects has been monitored during Campaign 6 and represents a nearly unbiased subsample of the population of small Solar System bodies. We derived precise periods and amplitudes for all Trojans, and found their distributions to be compatible with the previous statistics. We point out, however, that ground-based rotation periods are often unreliable above 20h, and we find an overabundance of rotation periods above 60h compared with other minor planet populations. From amplitude analysis we derive a rate of binarity of 20$\\pm$ 5%. Our spin rate distribution confirms the previously obtained spin barrier of ~5h and the corresponding ~0.5 g cm$^{-3}$ cometary-like density limit, also suggesting a high internal porosity for Jovian Trojans. One of our targets, asteroid 65227 exhibits a double rotation period, which can either be due to binarity or the outcome of a recen...

  15. Vitamin K2 Prevents Glucocorticoid-induced Osteonecrosis of the Femoral Head in Rats.

    Science.gov (United States)

    Zhang, Yue-Lei; Yin, Jun-Hui; Ding, Hao; Zhang, Wei; Zhang, Chang-Qing; Gao, You-Shui

    2016-01-01

    Glucocorticoid medication is one of the most common causes of atraumatic osteonecrosis of the femoral head (ONFH), and vitamin K2 (VK2) has been shown to play an important and beneficial role in bone metabolism. In this study, we hypothesized that VK2 could decrease the incidence of glucocorticoid-induced ONFH in a rat model. Using in vitro studies, we investigated how bone marrow-derived stem cells in the presence of methylprednisolone proliferate and differentiate, specifically examining osteogenic-related proteins, including Runx2, alkaline phosphatase and osteocalcin. Using in vivo studies, we established glucocorticoid-induced ONFH in rats and investigated the preventive effect of VK2. We employed micro-CT scanning, angiography of the femoral head, and histological and immunohistochemical analyses, which demonstrated that VK2 yielded beneficial effects for subchondral bone trabecula. In conclusion, VK2 is an effective antagonist for glucocorticoid on osteogenic progenitors. The underlying mechanisms include acceleration of BMSC propagation and promotion of bone formation-associated protein expression, which combine and contribute to the prevention of glucocorticoid-induced ONFH in rats.

  16. Cryogenic test of the 4 K / 2 K insert for the ARIEL e-Linac cryomodule

    Energy Technology Data Exchange (ETDEWEB)

    Laxdal, R. E.; Ma, Y.; Harmer, P.; Kishi, D.; Koveshnikov, A.; Muller, N.; Vrielink, A. [TRIUMF, 4004 Wesbrook Mall, Vancouver, BC (Canada); O' Brien, M. [University of British Columbia, Vancouver (Canada); Ahammed, M. [Variable Energy Cyclotron Center, Kolkata (India)

    2014-01-29

    The ARIEL project at TRIUMF requires a 50 MeV superconducting electron linac consisting of five nine cell 1.3 GHz cavities divided into three cryomodules with one, two and two cavities in each module respectively. LHe is distributed in parallel to each module at 4 K and at ∼1.2 bar. Each module has a cryogenic insert on board that receives the 4 K liquid and produces 2 K into a cavity phase separator. The module combines a 4 K phase separator, a plate and fin heat exchanger from DATE and a J-T valve expanding into the 2 K phase separator. The unit also supplies 4 K liquid to thermal intercepts in the module in siphon loops that return the vaporized liquid to the 4 K reservoir. For testing purposes the unit is outfitted with a dummy 2 K phase separator and thermal intercepts with variable heaters that mimic the final heat loads in order to test the cryogenic performance. The design of the 4 K / 2 K insert, the results of the cold tests and a summary of the test infrastructure including cryogenics services will be presented.

  17. Young "Dipper" Stars in Upper Sco and $\\rho$ Oph Observed by K2

    CERN Document Server

    Ansdell, M; Rappaport, S A; Jacobs, T L; LaCourse, D M; Jek, K J; Mann, A W; Wyatt, M C; Kennedy, G; Williams, J P; Boyajian, T S

    2015-01-01

    We present ten young ($\\lesssim$10 Myr) late-K and M dwarf stars observed in K2 Campaign 2 that host protoplanetary disks and exhibit quasi-periodic or aperiodic dimming events. Their optical light curves show $\\sim$10-20 dips in flux over the 80-day observing campaign with durations of $\\sim$0.5-2 days and depths of up to $\\sim$40%. These stars are all members of the $\\rho$ Ophiuchus ($\\sim$1 Myr) or Upper Scorpius ($\\sim$10 Myr) star-forming regions. To investigate the nature of these "dippers" we obtained: optical and near-infrared spectra to determine stellar properties and identify accretion signatures; adaptive optics imaging to search for close companions that could cause optical variations and/or influence disk evolution; and millimeter-wavelength observations to constrain disk dust and gas masses. The spectra reveal Li I absorption and H$\\alpha$ emission consistent with stellar youth (<50 Myr), but also accretion rates spanning those of classical and weak-line T Tauri stars. Infrared excesses are ...

  18. The stellar obliquity, planet mass, and very low albedo of Qatar-2 from K2 Photometry

    CERN Document Server

    Dai, Fei; Yu, Liang; Albrecht, Simon

    2016-01-01

    The Qatar-2 transiting exoplanet system was recently observed by the {\\it Kepler} telescope as part of {\\it K2} Campaign 6. The photometric time series has one-minute time sampling and a precision of about 690~ppm, after filtering out artifacts and spurious trends. We identify dozens of starspot-crossing events, when the planet eclipsed a relatively dark region of the stellar photosphere. The observed patterns in the sequence of these events demonstrate that the planet always transits over the same range of stellar latitudes, and therefore that the stellar obliquity is less than about 10$^\\circ$. We support this conclusion with two different modeling approaches: one based on explicit identification and timing of the events, and the other based on fitting the light curves with a spotted-star model. We are also able to refine the usual transit parameters and measure the stellar rotation period ($18.5 \\pm 1.9$~days), corresponding to a 'gyrochronological' age of $1.4 \\pm 0.3$ Gyr. Coherent flux variations with t...

  19. Synthesis of Platinum Nanoparticles from K2PtCl4 Solution Using Bacterial Cellulose Matrix

    Directory of Open Access Journals (Sweden)

    H. F. Aritonang

    2014-01-01

    Full Text Available Platinum (Pt nanoparticles have been synthesized from a precursor solution of potassium tetrachloroplatinate (K2PtCl4 using a matrix of bacterial cellulose (BC. The formation of Pt nanoparticles occurs at the surface and the inside of the BC membrane by reducing the precursor solution with a hydrogen gas reductant. The Pt nanoparticles obtained from the variations of precursor concentration, between 3 mM and 30 mM, and the formation of Pt nanoparticles have been studied using X-ray diffraction (XRD, scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDS, and thermogravimetry analysis (TGA. Based on X-ray diffraction patterns, Pt particles have sizes between 6.3 nm and 9.3 nm, and the Pt particle size increases with an increase in precursor concentration. The morphology of the Pt nanoparticles was observed by SEM-EDS and the content of Pt particles inside the membrane is higher than that on the surface of BC membranes. This analysis corresponds to the TGA analysis, but the TGA analysis is more representative in how it describes the content of Pt particles in the BC membrane.

  20. Nano K2Ti4O9 Whisker Enhanced Solid Lubrication Coating for Cutting Application

    Institute of Scientific and Technical Information of China (English)

    LIChang-sheng; ZHUCheng-shun; LIUYu; SONGChang-cai; LIUWan-zhang; YANKe-hong; FANZhen; DINGJian-ning; YANGJi-chang

    2004-01-01

    In order to decrease catting fluid and improve envirorunent, the catting fluid was replaced by solid lubricant. Four kinds of solid lubricants were tested on a high temperature friction tester, from which nano K2Ti4O9 whisker enhanced solid lubrication film was chosen. It was coated on the surface of catters and tested on a CA6140 lathe. At the rate of4OOr/min, the wear of the tool flank with solid lubrication,film is 1/6 of that without the film and it is even lower than that using catting fluid. With the increase of catting speed, the wear of the tool flank with solid lubrication,film is still lower than that without ,film, bat it is higher than that using catting fluid. Surface analyses by AFM , SEM and EDX reveal that the solid lubrication ,film can prevent Fe element of chips from diffusing the cutter surface ; adhesion of the cutter and chips is abated and the wear of the tool flank is obviously decreased.

  1. Characteristics of Laser Reflow Bumping of Sn3.5Ag and Sn3.5Ag0.5Cu Lead-Free Solder Balls

    Institute of Scientific and Technical Information of China (English)

    Yanhong TIAN; Chunqing WANG; Yarong CHEN

    2008-01-01

    Lead-free Sn3.5Ag and Sn3.5Ag0.5Cu solder balls were reflowed by laser to form solder bumps. Shear test was performed on the solder bumps, and SEM/EDX (scanning electron microscopy/energy dispersive X-ray spectrometer) was used to analyze the formation of intermetallic compounds (IMCs) at interface region. A finite element modeling on the temperature gradient and distribution at the interface of solder bump during laser reflow process was conducted to elucidate the mechanism of the IMCs growth direction. The results show that the parameters window for laser reflow bumping of Sn3.5Ag0.5Cu was wider than that of Sn3.5Ag. The shear strength of Sn3.5Ag0.5Cu solder bump was comparable to that of Sn3.5Ag solder bump, and was not affected obviously by laser power and irradiation time when appropriate parameters were used. Both laser power and heating time had a significant effect on the formation of IMCs. A continuous AuSn4 interrnetallic compound layer and some needle-like AuSn4 were observed at the interface of solder and Au/Ni/Cu metallization layer when the laser power is small. The formation of needle-like AuSn4 was due to temperature gradient at the interface, and the direction of temperature gradient was the preferred growth direction of AuSn4. With increasing the laser power and heating time, the needle-like AuSn4 IMCs dissolved into the bulk solder, and precipitated out once again during solidification along the grain boundary of the solder bump.

  2. The first salen-type ligands derived from 3',5'-diamino-3',5'-dideoxythymidine and -dideoxyxylothymidine and their corresponding copper(II complexes

    Directory of Open Access Journals (Sweden)

    Koth Daniel

    2006-08-01

    Full Text Available Abstract Background There are many nucleoside metal complexes known. According to observations made, only very few of them reveal their central ion to be co-ordinated by the sugar part of their molecules. The regio- and stereospecific exchange of the hydroxyl groups at the sugar moiety by chelating units improves its complexation ability and should give access to a new class of chiral ligands. Results In this paper we present the synthesis of 3',5'-diamino substituted thymidines with ribo- as well as xylo-configuration and the preparation of copper(II complexes derived from their corresponding Schiff bases. Starting from thymidine, the amino derivatives were prepared in a three and four step reaction sequence respectively. The absolute configuration of the ligands was proved by the three-bond 1H-1H spin spin coupling constants 3J obtained by NMR-studies. Condensation of the amino derivatives with salicylic aldehydes resulted in the corresponding diimines, which represent a new class of chiral salen-type ligands. All ligands formed uncharged stable copper(II complexes. The structure of 3',5'-bis(3,5-di-tert-butylsalicylaldiminato-3',5'-dideoxyxylothymidine-copper(II could be determined by single crystal X-ray structure analysis. The copper centre in this complex has distorted tetrahedral coordination geometry. Conclusion For the synthesis of 3',5'-diamino-3',5'-dideoxy thymidines with xylo- as well as ribo-configuration an effective synthesis pathway has been developed. Their corresponding salicylidene imines form stable coordination compounds with copper(II ions. They represent the first salen type complexes of nucleosides with this substitution pattern.

  3. 2-(2,4-Dichlorophenyl-3-[5-(3,5-dimethylphenyl-1,3,4-thiadiazol-2-yl]thiazolidin-4-one

    Directory of Open Access Journals (Sweden)

    Rong Wan

    2008-01-01

    Full Text Available The title compound, C19H15Cl2N3OS2, was synthesized by the reaction of N-(2,4-dichlorophenyl-5-(3,5-dimethylphenyl-1,3,4-thiadiazol-2-amine and mercaptoacetic acid. The thiazolidinone ring adopts a twist conformation. The 2,4-dichlorophenyl ring is almost perpendicular to the thiadiazole ring, the dihedral angle being 82.8 (2°. The 3,5-dimethylphenyl ring is nearly coplanar with the thiadiazole ring, the dihedral angle being 2.7 (2°. An intramolecular C—H...N hydrogen bond is present.

  4. Comparison on Quality Compositions of Broken Black Tea between Elite Germplasm in Yunnan and Kenyan Cultivar 6/8%云南优质红碎茶资源与肯尼亚品种6/8的品质成分比较研究

    Institute of Scientific and Technical Information of China (English)

    李晓霞; 杨盛美; 宋维希; 马玲; 刘本英; 汪云刚; 唐一春

    2014-01-01

    In order to promote the screen of quality broken black tea variety and the improvement of general quality of broken black tea in Yunnan, and to strengthen the international market competitiveness of it, the chemical compositions, the quality and the thealfavins content of broken black tea were analyzed and compared between 20 samples of elite germplasm in Yunnan and Kenyan cultivar 6/8. The results showed that in the samples of elite germplasm in Yunnan, the contents of tea polyphenols, caffeine, amino acid, water extracts, and ratio of tea polyphenols to amino acid were 26.00%~36.23%, 3.70%~5.75%, 1.71%~4.18%, 41.73%~49.24%, and 6.22~21.19, respectively. t-test results indicated that there were not signiifcant differences in biochemical components between 20 samples of elite germplasm in Yunnan and Kenyan cultivar 6/8, the sensory score of seven samples of elite germplasm in Yunnan exceeded that of Kenyan cultivar 6/8, the thealfavin content of nine samples of elite germplasm in Yunnan exceeded that of Kenyan cultivar 6/8. Therefore, Yunnan large-leaf tea germplasm resources have material basis for processing quality broken black tea.%为了加速优质红碎茶品种的选育,促进云南红碎茶总体品质的提升及增强国际市场竞争力,对20份云南优质红碎茶资源与肯尼亚品种6/8的化学成分、红碎茶品质、茶黄素含量进行了分析比较。结果表明,云南优质红碎茶资源的茶多酚含量为26.00%~36.23%,咖啡碱含量为3.70%~5.75%,氨基酸含量为1.71%~4.18%,水浸出物含量为41.73%~49.24%,酚氨比为6.22~21.19,测验表明,云南优质红碎茶资源与肯尼亚品种6/8的生化成分没有显著性差异,红碎茶感官审评得分超过肯尼亚品种6/8的有7份,茶黄素含量超过肯尼亚品种6/8的有9份,云南大叶茶资源具备加工优质红碎茶的物质基础。

  5. Fourier transform Raman spectroscopy of the four crystallographic phases of {alpha}, {beta}, {gamma} and {epsilon} 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.0{sup 5,9}.0{sup 3,11}]dodecane (HNIW, CL-20)

    Energy Technology Data Exchange (ETDEWEB)

    Goede, Patrick; Latypov, Nikolaj V.; Oestmark, Henric [Department of Energetic Materials, Grindsjoen Research Center, Swedish Defence Research Agency, FOI, SE-147 25 Tumba (Sweden)

    2004-08-01

    Fourier transform Raman Spectroscopy (Nd: YAG laser at 1064 nm) was used to characterize the four stable phases of 2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.0{sup 5,9}.0{sup 3,11}]dodecane (HNIW, CL-20). Raman spectra are reported over the region from 0-4000 cm{sup -1}{sub ,} relative to the laser line. A tentative assignment of the most predominant Raman peaks was made with the aid of QM calculations at the B3LYP/6-31G(d) level. A method for detecting polymorphic impurities in {epsilon}-CL-20 was also developed. The detection level for polymorphic impurities was determined to be below 2%. A method for producing {gamma}-CL-20 is also presented. (Abstract Copyright [2004], Wiley Periodicals, Inc.)

  6. Investigation of Pseudothrombocytopenia(PTCP)Caused by Using EDTA-K2 Decoagulant%EDTA-K2抗凝剂致假性血小板减少的探讨

    Institute of Scientific and Technical Information of China (English)

    林志远; 黄建玲

    2008-01-01

    目的 探讨EDTA-K2抗凝剂对假性血小板减少的影响并探讨其解决方法 .方法 用不同的检测方法 对怀疑由于EDTA-K2抗凝剂致假性血小板减少标本进行测定,并以血小板计数手工法为参考方法,比较不同方法 有无显著差异.结果 怀疑对EDTA-K2抗凝剂敏感标本,在以EDTA-K2抗凝的血标本中血小板计数可随时间延长而明显减少(P<0.005);在枸橼酸钠抗凝血、末梢血中血小板计数未见明显减少(P>0.005).结论 血小板在体外在(EDTA-K2)抗凝时,明显簇集者不常见,但一旦发生,则可引起PLT明显减少.可用末梢血或橼酸钠抗凝血代替.

  7. Relative K2 of Rings With SR2*(R,I) Condition%满足SR2*(R,I)条件的环的相对K2

    Institute of Scientific and Technical Information of China (English)

    储诚浩; 李忠华; 宋光天

    2006-01-01

    设I是环R的理想,称(R,I)满足SR2*(R,I)条件,如果它满足SR2(R,I)条件,并且对任意的a,b∈I,存在一个I-单位半正则元t∈R,使得1+a(b-t)∈U(R,I).称环R带许多单位半正则元,如果它满足SR2*(R,R)条件.本文证明,如果(R,I)满足SR2*(R,I)条件,则S(R,I)=L(I)( )(I)L(I)H(R,I),且相对K2群K12(R,I)(K2(R,I))包含在H(R,I)(H(R( )I,O( )I))中;进而,若I包含于R的中心,则K12(R,I)和K2(R,I)由相对Dennis-Stein符号生成.特别的,如果R是带许多单位半正则元的环,那么K2(R)包含在H(R)中;进而,若R是交换的,则K2(R)由Dennis-Stein符号生成.在SR2(R,I)条件下,本文证明了K2(n,R,I)具有满稳定性,其中n≥3.%Let R be a ring and I an ideal of R.(R,I)is said to satisfy the SR2*(R,I)condition if the SR2(R,I)condition is satisfied, and for any a, b ∈ I, there exists anI-unit semi-regular element t ∈ R such that 1+a(b-t)∈ U(R,I). A ring R is said to have many unit semi-regular elements if the SR2*(R,R)condition is satisfied. It is proved in this paper that if the SR2*(R,I)condition is satisfied, then S(R,I)= L(I)( )(I)L(I)H(R,I)and the relative K2 group K12(R,I)(K2(R,I))is contained in H(R,I)(H(R( )I,O( )I)); and if furthe R,I is contained in the center of R, then K12(R,I)and K2(R,I)are generated by the relative Dennis-Stein symbols. In particula R,I f R has many unit semi-regular elements, then K2(R)is contained in H(R);and if further, R is commutative, then K2(R)is generated by the Dennis Stein symbols. The surjective stability of K2(n,R,I)is also obtained under the SR2(R,I)condition and n ≥ 3.

  8. Accurately Predicting the Density and Hydrostatic Compression of Hexahydro-1,3,5-Trinitro-1,3,5-Triazine from First Principles

    Institute of Scientific and Technical Information of China (English)

    SONG HuarJie; HUANG Feng-Lei

    2011-01-01

    @@ We predict the densities of crystalline hexahydro-1,3,5-trinitro-1,3,5-triazine(RDX)by introducing a factor of(1+1.5×10(-4)T)into the wavefunction-based potential of RDX constructed from first principles using the symmetry-adapted perturbation theory and the Williams-Stone-Misquitta method.The predicted values are within an accuracy of 1%of the density from O to 430K and closely reproduced the RDX densities under hydrostatic compression.This work heralds a promising approach to predicting accurately the densities of high explosives at temperatures and pressures to which they are often subjected,which is a long-standing issue in the field of energetic materials.%We predict the densities of crystalline hexahydro-l,3,5-trinitro-l,3,5-triazine (RDX) by introducing a factor of (1+1.5 x 10~* T) into the wavefunction-based potential of RDX constructed from first principles using the symmetry-adapted perturbation theory and the Williams-Stone-Misquitta method. The predicted values are within an accuracy of 1% of the density from 0 to 430 K and closely reproduced the RDX densities under hydrostatic compression. This work heralds a promising approach to predicting accurately the densities of high explosives at temperatures and pressures to which they are often subjected, which is a long-standing issue in the Beld of energetic materials.

  9. Untemplated nonenzymatic polymerization of 3',5'cGMP: a plausible route to 3',5'-linked oligonucleotides in primordia.

    Science.gov (United States)

    Šponer, Judit E; Šponer, Jiří; Giorgi, Alessandra; Di Mauro, Ernesto; Pino, Samanta; Costanzo, Giovanna

    2015-02-19

    The high-energy 3',5' phosphodiester linkages conserved in 3',5' cyclic GMPs offer a genuine solution for monomer activation required by the transphosphorylation reactions that could lead to the emergence of the first simple oligonucleotide sequences on the early Earth. In this work we provide an in-depth characterization of the effect of the reaction conditions on the yield of the polymerization reaction of 3',5' cyclic GMPs both in aqueous environment as well as under dehydrating conditions. We show that the threshold temperature of the polymerization is about 30 °C lower under dehydrating conditions than in solution. In addition, we present a plausible exergonic reaction pathway for the polymerization reaction, which involves transient formation of anionic centers at the O3' positions of the participating riboses. We suggest that excess Na(+) cations inhibit the polymerization reaction because they block the anionic mechanism via neutralizing the negatively charged O3'. Our experimental findings are compatible with a prebiotic scenario, where gradual desiccation of the environment could induce polymerization of 3',5' cyclic GMPs synthesized in liquid.

  10. Research progress of Vitamin K2 in perimenopausal and post-menopausal osteoporosis%维生素K2与围绝经期骨质疏松症关系的研究进展

    Institute of Scientific and Technical Information of China (English)

    孙娟; 葛声

    2011-01-01

    维生素K是一类具有叶绿醌生物活性的萘醌基团的衍生物,主要有两种存在形式,一种是叶绿醌,即维生素K1;另一类是甲基萘醌类,即维生素K2.近年来研究认为,维生素K2是围绝经期及绝经后骨质疏松症关键的影响因素,它通过将骨钙素中的谷氨酸残基羧化成γ-羧化谷氨酸残基促进骨形成;是骨特异性转录调节因子,促进了成骨细胞标志物的表达;并抑制骨吸收.这些结果为进一步研究围绝经期及绝经后骨质疏松症的治疗提供了新的根据,也为绝经期及绝经后骨质疏松症的治疗提供了新的靶点.%Vitamin K is one of naphthoquinone derivatives with phylloquinone activity.Natural Vitamin K exists in two forms: the phylloquinone( Vitamin K1 ) and menaquinone( Vitamin K2).Recent studies show that Vitamin K2 is a key influence factor in perimenopausal and post-menopausal osteoporosis.Vitamin K2 can promote the bone generation by turning the glutamate residues of Osteocalcin into γ-carboxyl glutamate residues.Vitamin K2 is a bone-specific transcription factor, and it promotes osteoblast marker expression,inhibits bone absorption.These new studies provide a new evidence and target for perimenopausal and postmenopausal osteoporosis treatment.

  11. Functional characterization of the vitamin K2 biosynthetic enzyme UBIAD1.

    Directory of Open Access Journals (Sweden)

    Yoshihisa Hirota

    Full Text Available UbiA prenyltransferase domain-containing protein 1 (UBIAD1 plays a significant role in vitamin K2 (MK-4 synthesis. We investigated the enzymological properties of UBIAD1 using microsomal fractions from Sf9 cells expressing UBIAD1 by analysing MK-4 biosynthetic activity. With regard to UBIAD1 enzyme reaction conditions, highest MK-4 synthetic activity was demonstrated under basic conditions at a pH between 8.5 and 9.0, with a DTT ≥0.1 mM. In addition, we found that geranyl pyrophosphate and farnesyl pyrophosphate were also recognized as a side-chain source and served as a substrate for prenylation. Furthermore, lipophilic statins were found to directly inhibit the enzymatic activity of UBIAD1. We analysed the aminoacid sequences homologies across the menA and UbiA families to identify conserved structural features of UBIAD1 proteins and focused on four highly conserved domains. We prepared protein mutants deficient in the four conserved domains to evaluate enzyme activity. Because no enzyme activity was detected in the mutants deficient in the UBIAD1 conserved domains, these four domains were considered to play an essential role in enzymatic activity. We also measured enzyme activities using point mutants of the highly conserved aminoacids in these domains to elucidate their respective functions. We found that the conserved domain I is a substrate recognition site that undergoes a structural change after substrate binding. The conserved domain II is a redox domain site containing a CxxC motif. The conserved domain III is a hinge region important as a catalytic site for the UBIAD1 enzyme. The conserved domain IV is a binding site for Mg2+/isoprenyl side-chain. In this study, we provide a molecular mapping of the enzymological properties of UBIAD1.

  12. VizieR Online Data Catalog: Pleiades members with K2 light curves. II. (Rebull+, 2016)

    Science.gov (United States)

    Rebull, L. M.; Stauffer, J. R.; Bouvier, J.; Cody, A. M.; Hillenbrand, L. A.; Soderblom, D. R.; Valenti, J.; Barrado, D.; Bouy, H.; Ciardi, D.; Pinsonneault, M.; Stassun, K.; Micela, G.; Aigrain, S.; Vrba, F.; Somers, G.; Gillen, E.; Collier, Cameron A.

    2016-11-01

    The observations and methods are discussed in detail in Paper I (Rebull et al. 2016, Cat. J/AJ/152/113). Here we simply summarize the main points. Members of the Pleiades were observed in K2 campaign 4, which lasted for 72 days. All of the stars in this sample were observed in the long-cadence (~30 minute exposure) mode. We looked for periods using the Lomb-Scargle (LS; Scargle 1982ApJ...263..835S) approach. For stars of the mass range considered here, the periods that we measure are, by and large, starspot-modulated rotation periods. Spot modulation is the simplest explanation for sinusoidal (or sinusoidal-like) variations where there are changes over an entire orbital phase. We assembled a catalog of literature data for our targets. The most important values obtained from this search are (V-Ks)0 (measured or inferred; see Paper I, Rebull et al. 2016, Cat. J/AJ/152/113) and membership (see Paper I). Cross-identifications between the EPIC number, R.A./decl., and common literature names are in Paper I. Out of the 1020 light curves of candidate Pleiades members from which we started, there are 775 high-confidence members, with 51 more lower-confidence members (for a total of 826 members). Out of those 775 (best members), 716 (92.4%) have at least one measured period that we believe in the overwhelming majority of cases to be a rotation period and due to starspots. Including the lower-confidence members, 759/826 (91.9%) have at least one measured period (see Table2). The period distribution is strongly peaked at P<1day with typical amplitudes of ~0.03mag. (1 data file).

  13. YOUNG “DIPPER” STARS IN UPPER SCO AND OPH OBSERVED BY K2

    Energy Technology Data Exchange (ETDEWEB)

    Ansdell, M.; Williams, J. P. [Institute for Astronomy, University of Hawai‘i at Mānoa, Honolulu, HI (United States); Gaidos, E. [Department of Geology and Geophysics, University of Hawai‘i at Mānoa, Honolulu, HI (United States); Rappaport, S. A. [Physics Department and Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, Cambridge, MA (United States); Mann, A. W. [Department of Astronomy, The University of Texas at Austin, Austin, TX (United States); Wyatt, M. C.; Kennedy, G. [Institute of Astronomy, University of Cambridge, Madingley Road, Cambridge (United Kingdom); Boyajian, T. S. [Department of Astronomy, Yale University, New Haven, CT (United States); Jacobs, T. L.; LaCourse, D. M.; Jek, K. J.

    2016-01-10

    We present ten young (≲10 Myr) late-K and M dwarf stars observed in K2 Campaign 2 that host protoplanetary disks and exhibit quasi-periodic or aperiodic dimming events. Their optical light curves show ∼10–20 dips in flux over the 80-day observing campaign with durations of ∼0.5–2 days and depths of up to ∼40%. These stars are all members of the ρ Ophiuchus (∼1 Myr) or Upper Scorpius (∼10 Myr) star-forming regions. To investigate the nature of these “dippers” we obtained: optical and near-infrared spectra to determine stellar properties and identify accretion signatures; adaptive optics imaging to search for close companions that could cause optical variations and/or influence disk evolution; and millimeter-wavelength observations to constrain disk dust and gas masses. The spectra reveal Li i absorption and Hα emission consistent with stellar youth (<50 Myr), but also accretion rates spanning those of classical and weak-line T Tauri stars. Infrared excesses are consistent with protoplanetary disks extending to within ∼10 stellar radii in most cases; however, the sub-millimeter observations imply disk masses that are an order of magnitude below those of typical protoplanetary disks. We find a positive correlation between dip depth and WISE-2 (Wide-field Infrared Survey Explorer-2) excess, which we interpret as evidence that the dipper phenomenon is related to occulting structures in the inner disk, although this is difficult to reconcile with the weakly accreting aperiodic dippers. We consider three mechanisms to explain the dipper phenomenon: inner disk warps near the co-rotation radius related to accretion; vortices at the inner disk edge produced by the Rossby Wave Instability; and clumps of circumstellar material related to planetesimal formation.

  14. Testing the concept of hypervalency: charge density analysis of K2SO4.

    Science.gov (United States)

    Schmøkel, Mette S; Cenedese, Simone; Overgaard, Jacob; Jørgensen, Mads R V; Chen, Yu-Sheng; Gatti, Carlo; Stalke, Dietmar; Iversen, Bo B

    2012-08-06

    One of the most basic concepts in chemical bonding theory is the octet rule, which was introduced by Lewis in 1916, but later challenged by Pauling to explain the bonding of third-row elements. In the third row, the central atom was assumed to exceed the octet by employing d orbitals in double bonding leading to hypervalency. Ever since, polyoxoanions such as SO(4)(2-), PO(4)(3-), and ClO(4)(-) have been paradigmatic examples for the concept of hypervalency in which the double bonds resonate among the oxygen atoms. Here, we examine S-O bonding by investigating the charge density of the sulfate group, SO(4)(2-), within a crystalline environment based both on experimental and theoretical methods. K(2)SO(4) is a high symmetry inorganic solid, where the crystals are strongly affected by extinction effects. Therefore, high quality, very low temperature single crystal X-ray diffraction data were collected using a small crystal (∼30 μm) and a high-energy (30 keV) synchrotron beam. The experimental charge density was determined by multipole modeling, whereas a theoretical density was obtained from periodic ab initio DFT calculations. The chemical bonding was jointly analyzed within the framework of the Quantum Theory of Atoms In Molecules only using quantities derived from an experimental observable (the charge density). The combined evidence suggests a bonding situation where the S-O interactions can be characterized as highly polarized, covalent bonds, with the "single bond" description significantly prevailing over the "double bond" picture. Thus, the study rules out the hypervalent description of the sulfur atom in the sulfate group.

  15. The Stellar Obliquity, Planet Mass, and Very Low Albedo of Qatar-2 from K2 Photometry

    Science.gov (United States)

    Dai, Fei; Winn, Joshua N.; Yu, Liang; Albrecht, Simon

    2017-01-01

    The Qatar-2 transiting exoplanet system was recently observed in short-cadence mode by Kepler as part of K2 Campaign 6. We identify dozens of starspot-crossing events, when the planet eclipses a relatively dark region of the stellar photosphere. The observed patterns of these events demonstrate that the planet always transits over the same range of stellar latitudes and, therefore, that the stellar obliquity is less than about 10°. We support this conclusion with two different modeling approaches: one based on explicit identification and timing of the events and the other based on fitting the light curves with a spotted-star model. We refine the transit parameters and measure the stellar rotation period (18.5 ± 1.9 days), which corresponds to a “gyrochronological” age of 1.4 ± 0.3 Gyr. Coherent flux variations with the same period as the transits are well modeled as the combined effects of ellipsoidal light variations (15.4 ± 4.8 ppm) and Doppler boosting (14.6 ± 5.1 ppm). The magnitudes of these effects correspond to a planetary mass of 2.6+/- 0.9 {M}{Jup} and 3.9+/- 1.5 {M}{Jup}, respectively. Both of these independent mass estimates agree with the mass determined by the spectroscopic Doppler technique (2.487+/- 0.086 {M}{Jup}). No occultations are detected, giving a 2σ upper limit of 0.06 on the planet’s visual geometric albedo. We find no evidence for orbital decay, although we are only able to place a weak lower bound on the relevant tidal quality factor: {Q}\\star \\prime > 1.5× {10}4 (95% confidence).

  16. Liquid-Liquid Equilibrium for 1-Butanol-Water-KF and 1-Butanol-Water-K2CO3 Systems

    Institute of Scientific and Technical Information of China (English)

    XU Wen-you; JI Min

    2005-01-01

    KF or K2CO3 was added into the 1-butanol-water system and two phases were formed: water-rich phase (water phase) and 1-butanol-rich phase (1-butanol phase). The liquid-liquid equilibrium (LLE) data for 1-butanol-water-KF and 1-butanol-water-K2 CO3 systems were measured at 25 C and showed that 1-butanol phase contained negligible salt and water phase contained negligible 1-butanol when the concentrations of KF and K2CO3 in the water phase were equal to or higher than 27. 11% and 31. 68%, respectively. Thus water could be separated efficiently from 1-butanol-water by adding KF or K2CO3 into the system. A theoretical calculation of LLE data was calculated by using the Pitzer theory to get water activity in the water phase, and by the models, such as the Wilson, NRTL or the UNIQUAC for the 1-butanol phase.For 1-butanol-water-KF system, the experimental data were found in good agreement with the calculated results by using Pitzer theory and Wilson equation, while for 1-butanol-water-K2CO3 system, the experimental data were found in good agreement with the calculated results by using Pitzer theory and UNIQUAC equation.

  17. IMMUNOASSAY METHODS FOR MEASURING ATRAZINE AND 3,5,6-TRICHLORO-2-PYRIDINOL IN FOODS

    Science.gov (United States)

    This chapter describes the use of enzyme-linked immunosorbent assay (ELISA) methods for the analysis of two potential environmental contaminants in food sample media, atrazine and 3,5,6-trichloro-2-pyridinol (3,5,6-TCP). Two different immunoassay formats are employed: a magnetic...

  18. 41 CFR 60-3.5 - General standards for validity studies.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true General standards for validity studies. 60-3.5 Section 60-3.5 Public Contracts and Property Management Other Provisions Relating to Public Contracts OFFICE OF FEDERAL CONTRACT COMPLIANCE PROGRAMS, EQUAL EMPLOYMENT...

  19. Synthesis and inhibitory effect on photosynthetic electron transport of 1,3,5-triazinylcarboxylic acid derivatives

    NARCIS (Netherlands)

    Fujimori, A.; Ikeda, Y.; Okano, R.; Hiraki, M.; Rensen, van J.J.S.; Boger, P.; Kohno, H.; Wakabayashi, K.

    2005-01-01

    This study relates to the modification of 2-benzylamino-4-methyl-6-trifluoromethyl-1,3,5-triazine. New 1,3,5-triazine compounds with an electron-withdrawing carboxyl group, e.g. ester group, substituted for the trifluoromethyl group, were synthesized and assayed for activity to inhibit

  20. IMMUNOASSAY METHODS FOR MEASURING ATRAZINE AND 3,5,6-TRICHLORO-2-PYRIDINOL IN FOODS

    Science.gov (United States)

    This chapter describes the use of enzyme-linked immunosorbent assay (ELISA) methods for the analysis of two potential environmental contaminants in food sample media, atrazine and 3,5,6-trichloro-2-pyridinol (3,5,6-TCP). Two different immunoassay formats are employed: a magnetic...

  1. 3,5-二溴-2-氨基吡嗪的合成研究%Synthesis of 3,5-dibromopyrazin-2-amine

    Institute of Scientific and Technical Information of China (English)

    姜卫东; 王瑜; 刘明星

    2016-01-01

    The 3 ,5-dibromopyrazin-2-amine was prepared and preparation parameters were optimized. The 2-Amino pyrazine was prepared by one-pot method via rearrangement and hydrolysis reaction using 2-cyanopyrazine. 3 ,5-dibromopyrazin-2-amine was synthesized using NBS as a bromating agent. The 3 , 5-dibromopyrazin-2-amine was identified by 1 H-NMR and MS. Meanwhile, the above preparation parameters were optimized. The total yield was 62%and the purity was more than 99% (HPLC). This method has some advantages of cheap materials, simple operation, lower environment pollution, a gentle reaction conditions and higher application value for the industrial production.%制备3,5-二溴-2-氨基吡嗪,并优化工艺。以2-氰基吡嗪为原料,经水解、重排一锅法得到2-氨基吡嗪,再用N-溴代丁二酰亚胺(NBS)溴化得3,5-二溴-2-氨基吡嗪。目标产物经1H-NMR和MS确认,与标准图谱相符;改进后的制备工艺所用原料和试剂工业上易得,价格低廉,操作简单,反应温和,产品纯度高,环境污染小,总收率达到62%,含量大于99%( HPLC),可适合规模化生产。

  2. Global gene expression in rat brain and liver after oral exposure to the explosive hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX).

    Science.gov (United States)

    Bannon, Desmond I; Dillman, James F; Hable, Michael A; Phillips, Christopher S; Perkins, Edward J

    2009-04-01

    RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) is a synthetic, high-impact, relatively stable explosive that has been in use since WWII. Exposure to RDX can occur in occupational settings (e.g., during manufacture) or through the inadvertent ingestion of contaminated environmental media such as groundwater. The toxicology of RDX is dominated by acute clonic-tonic seizures at high doses, which remit when exposure is removed and internal RDX levels decrease. Subchronic studies have revealed few other measurable toxic effects. The objective of this study was to examine the acute effects of RDX on the mammalian brain and liver using global gene expression analysis based on a predetermined maximum internal dose. Male Sprague-Dawley rats were given a single, oral, nonseizure-inducing dose of either 3 or 18 mg/kg RDX in a gel capsule. Effects on gene expression in the cerebral cortex and liver were assessed using Affymetrix Rat Genome 230 2.0 whole genome arrays at 0, 3.5, 24, and 48 h postexposure. RDX blood and brain tissue concentrations rapidly increased between 0 and 3.5 h, followed by decreases at 24 h to below the detection limit at 48 h. Pairwise comparison of high and low doses at each time point showed dramatic differential changes in gene expression at 3.5 h, the time of peak RDX in brain and blood. Using Gene Ontology, biological processes that affected neurotransmission were shown to be primarily down-regulated in the brain, the target organ of toxicity, while those that affected metabolism were up-regulated in the liver, the site of metabolism. Overall, these results demonstrate that a single oral dose of RDX is quickly absorbed and transported into the brain where processes related to neurotransmission are negatively affected, consistent with a potential excitotoxic response, whereas in the liver there was a positive effect on biological processes potentially associated with RDX metabolism.

  3. 土壤放线菌K2的筛选、鉴定及其抑菌活性初探%The Study on Antifungal Activity, Screening and Identification of Actinomycete K2 Strain from Soil

    Institute of Scientific and Technical Information of China (English)

    赵丽坤; 田永强; 高磊; 孙盈

    2013-01-01

      筛选具有抑制植物病原菌活性的放线菌是农用抗生素开发的基础。通过平板对峙法筛选出8株拮抗放线菌菌株,采用生长速率法测定获得一株对植物病原菌有较好抑菌作用的菌株K2,并采用抑制菌丝生长速率法对其抑菌谱进行研究,以及进行菌种鉴定。生长速率法试验表明,放线菌菌株K2发酵液对10种供试植物病原菌菌丝生长均有不同程度的抑制作用,其中以对尖孢镰刀菌(Fusarium oxysporum)抑制效果最好,抑菌率可达57.38%。根据形态学特征、生理生化特征和基于16S rDNA序列比对,鉴定菌株 K2属于链霉菌属(Streptomyces)的一个菌株。放线菌 K2的代谢产物具有较广的抑菌谱,对植物病原菌的防治有很大的研究开发潜力。%Screening antifungal actinomycetes were the foundation of agricultural antibiotics exploitation. The antifungal activity of 8 strains actinomycetes were studied by flat confrontation, one strain named K2 was got by mycelim growth rate, its antimicrobial spectrum was studied and strains identification with mycelim growth rate. The result of mycelium growth rate showed that K2 had a broad spectrum inhibitory activity to all the tested 10 plant pathogenic fungi. Among these, activity against Fusarium oxysporum was the highest with inhibition rate of 57.38%. The results based on morphological characteristics, physiological and biochemical characterization and 16S rDNA sequence analysis of strain K2 showed that it was possibly Streptomyces. The K2 strain displayed a broad spectrum inhibitory activity, which had great potential for controlling plant pathogens.

  4. Efeitos da fertirrigação de N e K2O na absorção de macronutrientes pela gravioleira Effects of fertirrigation of N and K2O on absorption of macronutrients by soursop crop

    Directory of Open Access Journals (Sweden)

    Roberto S. F. de H. Filho

    2006-03-01

    Full Text Available O objetivo deste trabalho foi avaliar o efeito de dosagens de N e K2O via água de irrigação na absorção de macronutrientes pela cultura da gravioleira. O experimento foi realizado no campo experimental da Embrapa Meio-Norte, situado no município de Teresina, PI (05º 05' S, 42º 48' W e 74,4 m de altitude. O delineamento experimental utilizado foi por blocos casualizados, com onze tratamentos e quatro repetições, com parcela útil composta de quatro plantas. Os tratamentos consistiram na aplicação de cinco dosagens de N (20, 120, 200, 280 e 380 kg ha-1 ano-1 combinadas com cinco dosagens de K2O (30, 180, 300, 420 e 570 kg ha-1 ano-1 de acordo com o modelo da matriz experimental Plan Plueba III, além de um tratamento com dosagem zero de ambos os nutrientes. Em nenhum dos tratamentos foi encontrado deficiência de N, K, Mg, S e P nas folhas da gravioleira. As dosagens de N, bem como as suas interações com as dosagens de K2O, não proporcionaram efeito significativo sobre os teores dos macronutrientes nas folhas da gravioleira. As dosagens de K2O influenciaram os teores dos macronutrientes Ca, K e Mg nas folhas da gravioleira.The objetive of this work was to evaluate the effect of doses of N and K2O through irrigation water on the absorption of macronutrients by soursop cultivation. The study was conducted at the experimental field of Embrapa - North, in Teresina, in the State of Piauí, Brazil (5º 05' S, 42º and 48' W. The experimental design was completely randomized blocks with eleven treatments and four repetitions. The treatments consisted in the application of five doses of N (20, 120, 200, 280 and 380 kg ha-1 year-1 combined with five doses of K2O (30, 180, 300, 420 and 570 kg ha-1 year-1 in agreement with the model of experimental matrix Plan Plueba III, besides a treatment with dose zero of both nutrients. No deficiency of N, K, Mg, S, and P in the soursop leaves was found in any treatment. The doses of N did not provide

  5. Thermoelectric Properties of P-type Skutterudites YbxFe3.5Ni0.5Sb12 (0.8 x 1)

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Jung Y [GM R& D and Planning, Warren, Michigan; Ye, Zuxin [GM Research and Development Center; Tessema, M. [GM Research and Development Center; Waldo, R.A. [GM Research and Development Center; Salvador, James R. [GM R& D and Planning, Warren, Michigan; Yang, Jihui [General Motors Corporation; Cai, Wei [ORNL; Wang, Hsin [ORNL

    2012-01-01

    P-type skutterudites, with nominal compositions YbxFe3.5Ni0.5Sb12 (0.8 x 1), have been synthesized by induction melting with subsequent annealing, and their thermoelectric properties evaluated from 3.5 K to 745 K to assess their suitability for thermoelectric based waste heat recovery applications. We report results for the synthesis and measurements of Seebeck coefficient (S), electrical resistivity ( ), thermal conductivity ( ), Hall coefficient (RH), and effective mass (m*/m0) of YbxFe3.5Ni0.5Sb12 (0.8 x 1). Powder x-ray diffraction and electron probe microanalysis (EPMA) show that this system has a narrow filling fraction range of x ~ 0.84 to 0.86 for Yb in the crystallographic voids. All samples show positive RH for the entire temperature range studied with carrier concentrations ranging from 9.6 1020 to 2.8 1021 cm-3 at room temperature. Relatively high values of S result in high power factors up to 17 Wcm-1K-2 at room temperature. However, large values of and a sharp reduction in the S at high temperature due to bipolar conduction prevent the attainment of high thermoelectric figure of merit.

  6. Synthesis, Mass Spectrometric Studies, and Biological Evaluation of 3,5-Dimethoxyhomophthalic Acid and Related Compounds

    Institute of Scientific and Technical Information of China (English)

    GHULAM Qadeer; NASIM Hasan-rama; FAN Zhi-jin

    2007-01-01

    3,5-Dimethoxyhomophthalic acid was synthesized in four steps from 3,5-dimethoxycinnamic acid via a series of reactions including cyclization of 3-(3' ,5'-dimethoxyphenyl) propionic acid to 5,7-dimethoxy-1-indanone and oxidative decomposition of methyl-2-hydroxy-2-[ 5,7-dimethyoxy-1-oxo-1H-inden-2 (3H) -ylidene ] acetate to 3,5-dimethoxyhomophthalic acid. The synthesized compounds were characterized by elemental analysis, IR, 1H NMR, and MS. The biological evaluation experiments of 3,5-dimthoxyhomophthalic acid and the related synthesized compounds were also carried out. Naturally occurring biologically active isocoumarins were prepared in a single step by the condensation of the homophthalic acid with appropriate acid chlorides.

  7. Preparation and characterization of interfacial polymerised membrane from 3,5-diaminobenzoic acid

    Directory of Open Access Journals (Sweden)

    Abdul Latif Ahmad

    2002-11-01

    Full Text Available Thin Film Composite (TFC polyamide membranes were prepared by interfacially polymerizing secondary amide (piperazine and highly hydrophilic aromatic primary amide (3,5-diaminobenzoic acid with trimesoyl chloride onto the polysulfone support. The salt rejection and flux of these composite membranes were measured at various feed pressures. Incorporation of the 3,5-diaminobenzoic acid cause an increase in hydraulic permeance and flux but loss in the rejection of NaCl and Na2SO4. Higher concentration of 3,5-diaminobenzoic acid produced a loose and defected skin layer but small quantity of 3,5-diaminobenzoic acid can improved the flux and rejection of Na2SO4. The reaction between the 3,5-diaminobenzoic acid, piperazine and trimesoyl chloride was further confirmed using Fourier Transform Infrared (FTIR.

  8. Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics.

    Science.gov (United States)

    Li, Xinran; Wang, Xiang; Zhang, Xiaoli; Zhao, Mingkun; Tsang, Wai Lok; Zhang, Yanling; Yau, Richard Gar Wai; Weisman, Lois S; Xu, Haoxing

    2013-12-24

    Phosphatidylinositol 3,5-bisphosphate [PI(3,5)P2] is a low-abundance phosphoinositide presumed to be localized to endosomes and lysosomes, where it recruits cytoplasmic peripheral proteins and regulates endolysosome-localized membrane channel activity. Cells lacking PI(3,5)P2 exhibit lysosomal trafficking defects, and human mutations in the PI(3,5)P2-metabolizing enzymes cause lysosome-related diseases. The spatial and temporal dynamics of PI(3,5)P2, however, remain unclear due to the lack of a reliable detection method. Of the seven known phosphoinositides, only PI(3,5)P2 binds, in the low nanomolar range, to a cytoplasmic phosphoinositide-interacting domain (ML1N) to activate late endosome and lysosome (LEL)-localized transient receptor potential Mucolipin 1 (TRPML1) channels. Here, we report the generation and characterization of a PI(3,5)P2-specific probe, generated by the fusion of fluorescence tags to the tandem repeats of ML1N. The probe was mainly localized to the membranes of Lamp1-positive compartments, and the localization pattern was dynamically altered by either mutations in the probe, or by genetically or pharmacologically manipulating the cellular levels of PI(3,5)P2. Through the use of time-lapse live-cell imaging, we found that the localization of the PI(3,5)P2 probe was regulated by serum withdrawal/addition, undergoing rapid changes immediately before membrane fusion of two LELs. Our development of a PI(3,5)P2-specific probe may facilitate studies of both intracellular signal transduction and membrane trafficking in the endosomes and lysosomes.

  9. DFT Study of Hydrogen-Bonded 1,3,5-Triazine-Water Complexes

    Institute of Scientific and Technical Information of China (English)

    LI,Quan; HU,Jing-Dan; ZHAO,Ke-Qing

    2007-01-01

    The 1,3,5-triazine-water hydrogen bonding interactions have been investigated using the density functional theory B3LYP method and 6-31 + + G** basis, obtaining one, two and seven energy minima of the ground states for the 1,3,5-triazine-water, 1,3,5-triazine-(water)2 and 1,3,5-triazine-(water)3 complexes respectively. The fully optimized geometries and binding energies were reported for the various stationary points. The global minima of 1,3,5-triazine-(water)2 and 1,3,5-triazine-(water)3 complexes have a hydrogen bond N…H-O and a chain of water molecules, terminated by a hydrogen bond O…H-C. The binding energies are 13.38, 39.52 and 67.79 kJ/mol for the most stable 1,3,5-triazine-water, 1,3,5-triazine-(water)2 and 1,3,5-triazine-(water)3 complexes respectively, after the basis set superposition error and zero point energy corrections. The H-O symmetric stretching modes of water in the complexes are red-shifted relative to those of the monomer water. In addition, the NBO analysis indicates that inter-molecule charge transfer is 0.02145 e, 0.02501 e and 0.02777 e for the most stable 1∶1, 1∶2 and 1∶3 complexes between 1,3,5-triazine and water, respectively.

  10. Thermoelectric Properties of Hot-Pressed β-K2Bi8Se13- x S x Materials

    Science.gov (United States)

    Kyratsi, Theodora; Ioannou, Maria

    2013-07-01

    In this work, hot-pressed pellets of the K2Bi8Se13 family of compounds were prepared for the first time. The pellet fabrication of selected members of the K2Bi8Se13- x S x series was studied. Sintering parameters, such as temperature, pressure, and duration, were investigated based on a statistical design- of-experiments approach to identify the optimum conditions for fabrication of high-quality pellets. These optimum conditions were then applied for the K2Bi8Se13- x S x series, and the thermoelectric properties of the stoichiometric members for x = 0, 4, 6, and 8 were studied. Doping experiments were also investigated using sulfur excess in the x = 6 member in an attempt to modify its properties.

  11. A Search and Exploration of Multi-Exoplanet Systems Via Transit Timing Variation (TTV) Algorithms for the K2 Mission

    Science.gov (United States)

    Dholakia, Shishir; Dholakia, Shashank; Cody, Ann Marie

    2017-01-01

    We use the K2 mission to search for and analyze multi-planet systems with the goal of performing a scalable search for multi-planet systems using the transit timing variation (TTV) method. We developed an algorithm in Python to perform a search for synodic TTVs from multi-planet systems. The algorithm analyzes images taken by the K2 mission, creates light curves, and searches for TTVs on the order of a few minutes for every star in the images. We detected 4 potential TTV signals of which 3 are possible new discoveries. One of the systems has known multiple transiting planets and exhibits TTVs consistent with theoretical and previously published TTVs from n-body simulations. Another exoplanet system exhibits possible TTVs consistent with at least two giant planets. Our results demonstrate that a search for TTVs with the K2 mission is possible, though difficult.

  12. A quantitative description of the Na-K-2Cl cotransporter and its conformity to experimental data.

    Science.gov (United States)

    Benjamin, B A; Johnson, E A

    1997-09-01

    In epithelia, the Na-K-2Cl cotransporter cooperates with other transport mechanisms to produce transepithelial NaCl transport. The reaction cycle for the Na-K-2Cl cotransporter has been established experimentally, but whether it accounts, quantitatively, for experimental findings has yet to be established. The differential equations that describe the reaction cycle were formulated, and the steady-state solutions were obtained by digital computation. Conformity between this description and the experimental data obtained from the literature was explored by automatic searches for the sets of rate constants that yielded statistical best-fits to the experimental data. Fits were obtained from renal epithelial cell lines, HeLa cells, and duck erythrocytes. Results show that the reaction cycle for the Na-K-2Cl cotransporter conforms well, quantitatively, with the experimental data.

  13. Slab segmentation controls the interplate slip motion in the SW Hellenic subduction: New insight from the 2008 Mw 6.8 Methoni interplate earthquake

    Science.gov (United States)

    Sachpazi, M.; Laigle, M.; Charalampakis, M.; Sakellariou, D.; Flueh, E.; Sokos, E.; Daskalaki, E.; Galvé, A.; Petrou, P.; Hirn, A.

    2016-09-01

    We present an integrated approach of the seismic structure and activity along the offshore SW Hellenic subduction from combined observations of marine and land seismic stations. Our imaging of the slab top topography from teleseismic receiver function analysis at ocean bottom seismometers supports a trenchward continuation of the along-dip slab faults beneath the Peloponnesus. We further show that their morphostructural control accounts for the backstepping of the thrust contact of the Mediterranean Ridge accretionary wedge over the upper plate. Local seismic activity offshore SW Peloponnesus constrained by ocean bottom seismometer observations reveals a correlation with specific features of the forearc: the Matapan Troughs. We study the Mw 6.8 14.02.2008 interplate earthquake offshore SW Peloponnesus and show that its nucleation, rupture zone, and aftershocks sequence are confined to one slab panel between two adjacent along-dip faults and are thus controlled by not only the offshore slab top segmentation but also the upper plate sea-bottom morphology.

  14. Long-term validity of biological markers of psychopathy and criminal recidivism: follow-up 6-8 years after forensic psychiatric investigation.

    Science.gov (United States)

    Stalenheim, E Gunilla

    2004-01-01

    This study is a follow-up investigation of a forensic psychiatric sub-population 6-8 years after forensic psychiatric evaluation. The aim was to examine the long-term validity of biological markers of psychopathy and antisocial behavior over time. Data on criminal records were obtained at follow-up from the National Council for Crime Prevention. Basic data included findings of psychiatric and psychological assessments, as well as values for serum triiodothyronine (T3) and free thyroxin (FT4), and platelet monoamine oxidase (MAO) activity, all obtained during the forensic psychiatric examination. Criminal recidivists at follow-up had higher serum T3 levels than non-recidivists, and much higher values than normal controls, while their levels of free T4 were lower. The T3 levels in criminal recidivists correlated to psychopathy- and aggression-related personality traits as measured by the Karolinska Scale of Personality. In violent recidivists, a remarkably high correlation was noted between T3 levels and Irritability and Detachment, traits that have previously been linked to the dopaminergic system. Stepwise multiple regression analyses confirmed the relationships of T3 levels and platelet MAO activity with personality traits in criminal recidivists. The predictive validity of biological markers of psychopathy, T3 and platelet MAO, measured during forensic psychiatric investigation, is stable over time. The results indicate chronic alterations of the hypothalamic-pituitary-thyroid axis in this group of subjects.

  15. Socio-Economic and Environmental Factors Associated with Overweight and Obesity in Children Aged 6-8 Years Living in Five Italian Cities (the MAPEC_LIFE Cohort).

    Science.gov (United States)

    Grassi, Tiziana; De Donno, Antonella; Bagordo, Francesco; Serio, Francesca; Piscitelli, Prisco; Ceretti, Elisabetta; Zani, Claudia; Viola, Gaia C V; Villarini, Milena; Moretti, Massimo; Levorato, Sara; Carducci, Annalaura; Verani, Marco; Donzelli, Gabriele; Bonetta, Sara; Bonetta, Silvia; Carraro, Elisabetta; Bonizzoni, Silvia; Bonetti, Alberto; Gelatti, Umberto

    2016-10-11

    The prevalence of obesity among Italian children has reached such alarming levels as to require detailed studies of the causes of the phenomenon. A cross-sectional study was carried out in order to assess the weight status of 1164 Italian children aged 6-8 years (the Monitoring Air Pollution Effects on Children for Supporting Public Health Policy (MAPEC_LIFE) cohort) and to identify any associations between selected socio-economic and environmental factors and overweight/obesity. The data were obtained by means of a questionnaire given to parents, and any associations were examined by binomial logistic regression analyses. Overweight was found to be positively associated with male gender, parents of non-Italian origin, and parents who smoke, and negatively associated with the parents' level of education and employment. In addition, the frequency of overweight varied in relation to the geographical area of residence, with a greater prevalence of overweight children in the cities of central-southern Italy. This study highlights the need to implement appropriate obesity prevention programs in Italy, which should include educational measures concerning lifestyle for parents from the earliest stages of their child's life.

  16. An evaluation of the Kinect-Ed presentation, a motivating nutrition and cooking intervention for young adolescents in grades 6-8.

    Science.gov (United States)

    Santarossa, Sara; Ciccone, Jillian; Woodruff, Sarah J

    2015-09-01

    Recently, public health messaging has included having more family meals and involving young adolescents (YAs) with meal preparation to improve healthful diets and family dinner frequency (FDF). Kinect-Ed, a motivational nutrition education presentation was created to encourage YAs (grades 6-8) to help with meal preparation and ultimately improve FDF. The purpose of this study was to evaluate the Kinect-Ed presentation, with the goals of the presentation being to improve self-efficacy for cooking (SE), food preparation techniques (TECH), food preparation frequency (PREP), family meal attitudes and behaviours, and ultimately increase FDF. A sample of YAs (n = 219) from Southern Ontario, Canada, completed pre- and postpresentation surveys, measuring FDF, PREP, SE, and TECH. Kinect-Ed successfully improved participants' FDF (p < 0.01), PREP (p < 0.01), SE (p < 0.01), and TECH (<0.01). Overall, goals of the presentation were met. Encouraging YAs to help prepare meals and get involved in the kitchen may reduce the time needed from parents to prepare meals, and, in turn, allow more time for frequent family dinners.

  17. Theoretical investigations of a high density cage compound 10-(1-nitro-1, 2, 3, 4-tetraazol-5-yl)) methyl-2, 4, 6, 8, 12-hexanitrohexaazaisowurtzitane.

    Science.gov (United States)

    Zhang, Jian-ying; Du, Hong-chen; Wang, Fang; Gong, Xue-dong; Huang, Yin-sheng

    2012-01-01

    A new polynitro cage compound with the framework of HNIW and a tetrazole unit, i.e., 10-(1-nitro-1, 2, 3, 4-tetraazol-5-yl)) methyl-2, 4, 6, 8, 12-hexanitrohexaazaisowurtzitane (NTz-HNIW) has been proposed and studied by density functional theory (DFT) and molecular mechanics methods. Properties such as IR spectrum, heat of formation, thermodynamic properties, and crystal structure were predicted. The compound belongs to the Pbca space group, with the lattice parameters a = 15.07 Å, b = 12.56 Å, c = 18.34 Å, Z = 8, and ρ = 1.990 g·cm(-3). The stability of the compound was evaluated by the bond dissociation energies and results showed that the first step of pyrolysis is the rupture of the N-NO(2) bond in the side chain. The detonation properties were estimated by the Kamlet-Jacobs equations based on the calculated crystal density and heat of formation, and the results were 9.240 km·s(-1) for detonation velocity and 40.136 GPa for detonation pressure. The designed compound has high thermal stability and good detonation properties and is probably a promising high energy density compound (HEDC).

  18. Anti-Obesity Effect of 6,8-Diprenylgenistein, an Isoflavonoid of Cudrania tricuspidata Fruits in High-Fat Diet-Induced Obese Mice.

    Science.gov (United States)

    Jo, Yang Hee; Choi, Kyeong-Mi; Liu, Qing; Kim, Seon Beom; Ji, Hyeong-Jin; Kim, Myounghwan; Shin, Sang-Kyung; Do, Seon-Gil; Shin, Eunju; Jung, Gayoung; Yoo, Hwan-Soo; Hwang, Bang Yeon; Lee, Mi Kyeong

    2015-12-15

    Obesity, which is characterized by excessive fat accumulation, is associated with several pathological disorders, including metabolic diseases. In this study, the anti-obesity effect of 6,8-diprenylgenistein (DPG), a major isoflavonoid of Cudrania tricuspidata fruits was investigated using high fat-diet (HFD)-induced obese mice at the doses of 10 and 30 mg/kg for six week. The body weight of the DPG-treated groups was significantly lower compared to the HFD-treated group. In addition, fat accumulation in epididymal adipose tissue and liver was dramatically decreased in the HFD + DPG groups. The food efficiency ratios of the HFD + DPG groups were also lower compared to the HFD group with the same food intake. Metabolic parameters that had increased in the HFD group were decreased in the HFD + DPG groups. Further studies demonstrate that DPG efficiently reduces lipogenic genes by regulation of transcription factors, such as peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer-binding protein α (C/EBPα), and hormones, such as leptin and adiponection. DPG also regulates acetyl-CoA carboxylase (ACC) and hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) by AMP-activated protein kinase (AMPK) activation. Taken together, DPG is beneficial for the regulation of obesity, especially resulting from high fat intake.

  19. Space conditions during a month of a sequence of six M > 6.8 earthquakes ending with the tsunami of 26 December 2004

    Directory of Open Access Journals (Sweden)

    A. Papandreou

    2012-05-01

    Full Text Available This paper examines space and seismological data for the time period about one month before the giant Sumatra-Andaman strong (9.3 earthquake (EQ. The combination of seismological and space data reveals some interesting features for this time period: (1 six successive high speed solar wind streams obviously triggering a sudden increase of geomagnetic activity were all followed by strong to giant (M > 6.8 EQs, (2 the 6 strong EQs present certain spatial-temporal constraints, with the epicentre of the EQs occuring at the edges of the Pacific Plate (the Sumatra-Andaman EQ occurred at the end of this series of EQs, eastward of the first one, in a clockwise direction, (3 the EQs occurred after a sudden increase of geomagnetic activity, as inferred from the 3 h-Kp index, following a quiet geomagnetic period and (4 the time delay of the M > 6.2 earthquakes (in the broad area examined from the last maximum sudden Kp increase was on average ~1.5 days. These findings from the study of the Earth's space environment during the month preceding the Sumatra-Andaman giant (9.3 EQ provide new information for a possible better understanding of the Sun-magnetosphere-lithosphere coupling.

  20. The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis

    Directory of Open Access Journals (Sweden)

    E. Fisic

    2013-01-01

    Full Text Available Background and Aim. Early assessment of severity in acute pancreatitis (AP is a key measure to provide rational and effective management. The aim of our study is to determine the prognostic value of interleukins (IL 6, 8, and 10, soluble receptor for tumor necrosis factor (sTNFr, pancreatic elastase (E1, and C-reactive protein (CRP as predictors of systemic complications in AP. Patients and Methods. A hundred and fifty patients with confirmed AP were enrolled in the study. The severity of AP was defined according to Atlanta criteria. Measurements of interleukins and sTNFr were performed on the first day of admission. CRP and E1 levels were assessed on admission and after 48 hours. ROC analysis was performed for all parameters. Results. Interleukins and sTNFr significantly differentiated patients with systemic complications from those without. Elevation of IL-6 showed the highest significance as a predictor (. CRP and elastase levels did not differ between mild and severe cases on admission, but reached statistical significance when measured on the third day ( and , resp.. Conclusion. Our study confirmed that IL-6, IL-8, IL-10, and sTNFr measured on admission, and CRP and pancreatic elastase measured on third day of admission represent valuable prognostic factors of severity and systemic complications of AP.