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Sample records for izumi tsutomu nakamura

  1. Fandom unbound: Otaku culture in a connected world, edited by Mizuko Ito, Daisuke Okabe, and Izumi Tsuji [book review

    Directory of Open Access Journals (Sweden)

    Nele Noppe

    2015-03-01

    Full Text Available Review of Mizuko Ito, Daisuke Okabe and Izumi Tsuji, eds. Fandom unbound: Otaku culture in a connected world. New Haven, CT: Yale University Press, 2012, Kindle edition, $35; paperback, $38 (352p ISBN 978-0300158649.

  2. Salmonella isolated from the feces of migrating cranes at the Izumi Plain (2002-2008): serotype, antibiotic sensitivity and PFGE type.

    Science.gov (United States)

    Kitadai, Noriyuki; Ninomiya, Naoko; Murase, Toshiyuki; Obi, Takeshi; Takase, Kozo

    2010-07-01

    From November 2002 to February 2008, 2,251 crane feces were collected at the Izumi Plain in Kagoshima Prefecture. Salmonella enterica was isolated from 359 feces (15.9%), of which 332 (92.5%) were Salmonella Typhimurium (ST), 9 were S. Hvittingfoss/II, 4 were S. Abaetetuba, 3 were S. Enteritidis, 2 were S. Konstanz, 1 was S. Pakistan and 8 were untyped isolates, respectively. Against 12 antimicrobial agents, no resistant strains were found in 154 isolates examined, but one was found to be resistant to ampicillin. By pulsed-field gel electrophoresis (PFGE), all but one of the 68 ST isolates tested showed indistinguishable banding patterns; one had a different pattern. The results suggest that ST strains from the same origin would spread in crane flocks during their stay at Izumi Plain every winter.

  3. On the colour types in Lycodes nakamurae (Tanaka, 1914) and species composition of the subgenus Furcimanus (Perciformes: Zoarcidae: Lycodes) in the sea of Japan.

    Science.gov (United States)

    Saveliev, Pavel A; Balanov, Andrey A; Kukhlevskii, Andrey D

    2014-05-30

    Two colour types were revealed in a zoarcid fish of the subgenus Furcimanus, genus Lycodes, in the Sea of Japan. A comparison of morphometric, meristic and genetic characters in dark coloured and light coloured individuals suggests that the two colour morphs represent a single species, determined to be Lycodes nakamurae (Tanaka, 1914). Variability in colouration within L. nakamurae and a lack of morphological or molecular characters distinguishing L. nakamurae from L. nishimurai Shinohara & Shirai, 2005 suggest that the latter should be considered a synonym of L. nakamurae (Tanaka, 1914). A record of L. pectoralis in the waters of the Republic of Korea is regarded as a misidentification. Thus, we conclude that only one species of the Lycodes subgenus Furcimanus, L. nakamurae, with dark and light colour morphs as well as specimens of intermediate colouration, inhabits the Sea of Japan.

  4. Study of crystallization kinetics of peek thermoplastics using Nakamura equation

    Science.gov (United States)

    Chalid, Mochamad; Muhammad Joshua Y., B.; Fikri, Arbi Irsyad; Gregory, Noel; Priadi, Dedi; Fatriansyah, Jaka Fajar

    2018-04-01

    We have simulated the time evolution of relative crystallization of PEEK at various cooling rates (10, 15, 20 °C/min) and made comparison with the experiments. The simulation was conducted using Nakamura model which is a modified Avrami model. The model is a 1 cm radius of circle with the cooling plate which was placed in the upper part of the circle. The cooling plate temperature was varied in order to obtain particular cooling rates. The measurement point is located near upper boundary in order to minimize the heat transfer effect. The general trend of time evolution of crystallization was well captured although some discrepancies occured. These discrepancies may be attributed to the heat transfer effect and secondary crystallization.

  5. Nakamura Ryûtarô’s Anime, Serial Experiments, Lain (1998

    Directory of Open Access Journals (Sweden)

    Tamae KOBAYASHI PRINDLE

    2015-07-01

    Full Text Available This paper introduces Nakamura Ryūtarō’s anime, Serial Experiments, Lain (1998 as a new type of anime, a genre nameable as an “expository anime”, for the reason that it creates a diachronic story out of a synchronic aspect of a certain field of science. The overarching topic of Experiments is electronics, focusing on the comparison between digital and analogue communication systems. Experiments unfolds the rationales, potentials, and effects of the two types of communication systems using the perceptions of the major character, a thirteen-year old girl, Rein, as well as other supporting characters.

  6. Toda molecule and Tomimatsu-Sato solution-towards the complete proof of Nakamura's conjecture

    International Nuclear Information System (INIS)

    Fukuyama, Takeshi; Koizumi, Kozo

    2011-01-01

    We discuss the Nakamura's conjecture stating that the Tomimatsu-Sato black hole solution with an integer deformation parameter n is composed of the special solutions of the Toda molecule equation at the nth lattice site. From the previous work, in which the conjecture was partly analytically proved, we go further towards the final full proof by rearranging the rotation parameter. The proof is explicitly performed for the highest and lowest orders. Though the proof for all orders still remains unsolved, the prospect to the full proof becomes transparent and workable by our method. (paper)

  7. Report on the initial-stage survey of the new energy vision of the Izumi city area; 2001 nendo Izumi shi chiiki shin energy vision shoki dankai chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-02-01

    For the purpose of promoting the introduction of new energy and enhancing the awareness of it in Izumi City, Osaka Prefecture, an investigational study was conducted of the structure of energy consumption, existence amount of new energy, subjects in utilization of new energy, etc. The energy consumption amount of the city is increasing mostly in electric power in the residential sector, but is decreasing in the business sector and industrial sector. It is leveling off in the transportation sector, but only the consumption amount of gasoline is markedly increasing. In the potential amount of new energy utilization in the city, the rate of solar energy/clean energy vehicles was high. As a result of the study, the following were made clear: It is effective to introduce new energy mostly used for citizen such as the household use photovoltaic power system/solar heat use hot water supplier/hybrid private car. Of waste energy, wind energy, biomass energy and temperature difference energy, it is effective for city to take the initiative in introducing them. It is effective for city/proprietor to introduce the natural gas cogeneration. (NEDO)

  8. Investigation on initial stage of new energy vision in Izumi-otsu City in Osaka Prefecture. Report for fiscal 2000; Izumiotsushi chiiki shin energy vision shoki dankai chosa. 2000 nendo hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-02-01

    With objectives to achieve promotion of new energy introduction with the environment creating city as the basic concept, and to depict the future image of the city energies by clearly showing the way to suppressing environmental load, a new energy vision is being established. Fiscal 2000 has investigated the energy demand and supply conditions and existence quantity of new energies. The investigation results were put into order by the following seven items: 1) summary of the investigation, 2) district characteristics of Izumi-otsu City, 3) investigation on quantity of new energies available in the city, 4) investigation on the energy demand quantity, 5) putting the problems into order, 6) the Citizens' Energy Conference, and 7) summary of the investigation on examples of new energy utilization. Item 3 is composed of the new energies utilizable in Izumi-otsu City, and calculations of existence quantity of new energies that are to be utilized. The utilizable quantity of new energies is 9.9 times 10{sup 5} Gcal/year, which corresponds to about 60% of the energy used in fiscal 1990. (NEDO)

  9. Dawsonite and other carbonate veins in the Cretaceous Izumi Group, SW Japan: a natural support for fracture self-sealing in mud-stone cap-rock in CGS?

    Energy Technology Data Exchange (ETDEWEB)

    Okuyama, Yasuko; Funatsu, Takahiro; Fujii, Takashi [Institute for Geo-Resources and environment, GSJ, AISI, 1-1-1 Higashi, Central 7, Tsukuba, ibaraki 305-8567 (Japan); Take, Shuji [Kishiwada Nature Club, c/o Kishiwada City Natural History Museum, Sakai-Machi 5-6, Kishiwada, Osaka 596-0072 (Japan)

    2013-07-01

    Dawsonite-bearing carbonate veins are abundant in a compact mud-stone layer of the lower part of the Izumi Group, SW Japan. The mode of occurrence of the veins probably indicates fracturing and mineral sealing associated with upwelling of CO{sub 2}-rich fluid evolved in the reservoir beneath. The carbonate veins studied here can be a natural support to fracturing and healing of mud-stone cap-rock in the CO{sub 2} geological storage. (authors)

  10. Genetic characterization of low-pathogenic avian influenza viruses isolated on the Izumi plain in Japan: possible association of dynamic movements of wild birds with AIV evolution.

    Science.gov (United States)

    Nakagawa, Hiroko; Okuya, Kosuke; Kawabata, Toshiko; Matsuu, Aya; Takase, Kozo; Kuwahara, Masakazu; Toda, Shigehisa; Ozawa, Makoto

    2018-04-01

    The Izumi plain in Kagoshima Prefecture, Japan, is an overwintering site of endangered cranes (hooded cranes and white-naped cranes) and of many other migratory birds (including wild ducks) that are considered carriers of avian influenza viruses (AIVs). To assess the risks of a highly pathogenic avian influenza outbreak in the crane populations, we tested various environmental samples for AIVs in this area. In the 2014-2015 winter season, we isolated one AIV of the H6N2 subtype from the cranes' roost water and two AIVs of the H11N9 subtype from a crane fecal sample and a cloacal swab of a dead spot-billed duck. Genetic analysis of these AIV isolates indicated that our H6N2 isolate is genetically close to AIVs isolated from wild birds in Southeast Asian countries, except that the PB1 and NS genes belong to the North American virus lineage. All genes of the two H11N9 isolates are related to AIVs belonging to the Eurasian virus lineage. Notably, in our phylogenetic trees, H11 HA and N9 NA genes showing high sequence similarity to the corresponding genes of isolates from wild birds in South Africa and Spain, respectively, did not cluster in the major groups with recent wild-bird isolates from East Asia. These results suggest that AIVs with viral gene segments derived from various locations and bird species have been brought to the Izumi plain. These findings imply a possible association of dynamic movements of wild birds with AIV evolution.

  11. Characterization of gizzards and grits of wild cranes found dead at Izumi Plain in Japan.

    Science.gov (United States)

    Uegomori, Mima; Haraguchi, Yuko; Obi, Takeshi; Takase, Kozo

    2018-04-18

    We analyzed the gizzards, and grits retained in the gizzards of 41 cranes that migrated to the Izumi Plain during the winter of 2015/2016 and died there, either due to accident or disease. These included 31 Hooded Cranes (Grus monacha) and 10 White-naped Cranes (G. vipio). We determined body weight, gizzard weight, total grit weight and number per gizzard, and size, shape, and surface roundness of the grits. Average gizzard weights were 92.4 g for Hooded Cranes and 97.1 g for White-naped Cranes, and gizzard weight positively correlated with body weight in both species. Average total grit weights per gizzard were 19.7 g in Hooded Cranes and 25.7 g in White-naped Cranes, and were significantly higher in the latter. Average percentages of body weight to grit weight were 0.8% in Hooded Cranes and 0.5% in White-naped Cranes. Average grit number per gizzard was 693.5 in Hooded Cranes and 924.2 in White-naped Cranes, and were significantly higher in the latter. The average grit size was 2.8 mm in both species. No differences were found in the shape and surface roundness of grits between the two species. To the best of our knowledge, this is the first study on the grits retained in the gizzards of Hooded and White-naped Cranes.

  12. Semiclassical theory of electronically nonadiabatic chemical dynamics: Incorporation of the Zhu-Nakamura theory into the frozen Gaussian propagation method

    International Nuclear Information System (INIS)

    Kondorskiy, A.; Nakamura, H.

    2004-01-01

    The title theory is developed by combining the Herman-Kluk semiclassical theory for adiabatic propagation on single potential-energy surface and the semiclassical Zhu-Nakamura theory for nonadiabatic transition. The formulation with use of natural mathematical principles leads to a quite simple expression for the propagator based on classical trajectories and simple formulas are derived for overall adiabatic and nonadiabatic processes. The theory is applied to electronically nonadiabatic photodissociation processes: a one-dimensional problem of H 2 + in a cw (continuous wave) laser field and a two-dimensional model problem of H 2 O in a cw laser field. The theory is found to work well for the propagation duration of several molecular vibrational periods and wide energy range. Although the formulation is made for the case of laser induced nonadiabatic processes, it is straightforwardly applicable to ordinary electronically nonadiabatic chemical dynamics

  13. Contamination Status of Seven Elements in Hooded Cranes Wintering in South-West Kyushu, Japan: Comparison with Red-Crowned Cranes in Hokkaido, Japan.

    Science.gov (United States)

    Teraoka, Hiroki; Miyagi, Hasumi; Haraguchi, Yuko; Takase, Kozo; Kitazawa, Takio; Noda, Jun

    2018-05-31

    The hooded crane is designated as an endangered species. The cranes breed primarily in wetlands in southeast Russia and China in summer. Most of the hooded crane population winters in the Izumi plain in Japan. It is difficult to know the contamination status of their habitat because of their vast breeding area. We determined the levels of Cd, Pb, As, (total) Hg, Se, Zn, and Cu in the liver, kidney, and muscle of hooded cranes that were found dead in Izumi in the periods 2003-2006 and 2014-2015 compared with the levels in red-crowned cranes in Hokkaido, Japan, as the only cranes in which these elements had been studied extensively. There were no notable differences between levels of the seven elements in the two periods. Overall, tissue levels of the elements examined in hooded cranes were comparable to those in red-crowned cranes except for Hg and Se. Tissue levels of Hg and Se were clearly lower in hooded cranes than in red-crowned cranes that were found dead from 2000. One lead poisoning case was confirmed. The results suggest that Hooded cranes wintering in Izumi are not extensively contaminated with the seven elements examined.

  14. Solid-state synthesis and characterization of LiCoO2 and LiNiyCo1 ...

    Indian Academy of Sciences (India)

    Unknown

    than LiCoO2 and to possibly retain good lamellar struc- ture upon repeated cycling .... Julien C, Michael S S and Ziolkiewicz S 1999 Int. J. Inorg. Mater. 1 29. Kanno R, Kubo H, Kawamoto Y, Kamiyama T, Izumi F,. Takeda Y and Takano M 1994 ...

  15. Music and Movement for Young Children's Healthy Development

    Science.gov (United States)

    Izumi-Taylor, Satomi; Morris, Vivian Gunn; Meredith, Cathy D.; Hicks, Claire

    2012-01-01

    Young children enjoy moving around when they hear music. Children take pleasure in physical activities that contribute to their healthy development. Physical activities are vital to retain healthy bodies, and inactivity is one cause of obesity in young children (Dow, 2010; Izumi-Taylor & Morris, 2007). This article describes how teachers and…

  16. Paying for High- and Low-Quality Teaching

    Science.gov (United States)

    Schacter, John; Thum, Yeow Meng

    2004-01-01

    The extensive research on teacher quality has led to two conclusions. First, there are large and significant differences among teachers in terms of their capacity to improve student achievement. Second, these differences are not captured by common measures of teacher qualifications (E.A. Hanushek, Teacher quality, in: L.T. Izumi, W.M. Evers…

  17. Repression of Cell Proliferation and Androgen Receptor Activity in Prostate Cancer Cells by 2'-Hydroxyflavanone

    OpenAIRE

    大筆, 光夫; Ofude, Mitsuo

    2014-01-01

    博士論文要旨Abstract 以下に掲載：Anticancer Research 33(10) pp.4453-4461 2013. The International Institute of Anticancer Research. 共著者：MITSUO OFUDE, ATSUSHI MIZOKAMI, MISAKO KUMAKI, KOUJI IZUMI, HIROYUKI KONAKA, YOSHIFUMI KADONO, YASUHIDE KITAGAWA, MINKYOUNG SHIN, JIAN ZHANG, EVAN T. KELLER, MIKIO NAMIKI 　

  18. Diuron, Irgarol 1051 and Fenitrothion contamination for a river passing through an agricultural and urban area in Higashi Hiroshima City, Japan.

    Science.gov (United States)

    Kaonga, Chikumbusko Chiziwa; Takeda, Kazuhiko; Sakugawa, Hiroshi

    2015-06-15

    A study was conducted on the pesticides Diuron, Irgarol 1051 and Fenitrothion in Kurose River water, Higashi Hiroshima, Japan for a period of one year to assess the contribution of agriculture and urban activities on pesticide pollution of the river. Samples were analysed by a reverse phase HPLC system. The maximum pesticide concentrations were; 4620 ng/L, 50 ng/L and 370 ng/L for Diuron, Irgarol 1051 and Fenitrothion, respectively. While Diuron and Fenitrothion were detected at all sites, Irgarol 1051 was only present at Izumi, a high density urban and industrial area which also registered the highest concentrations of the pesticides. The pattern showed by Diuron and Fenitrothion was linked to farming activities. Also, Diuron and Fenitrothion concentration correlated with pesticide utilization data for Hiroshima Prefecture. Irgarol 1051 showed a different pattern to that of Diuron and Fenitrothion and its source was attributed to paint. It was noted that 78% and 42% of water samples at Izumi sampling site exceeded the European Union (EU) guidelines for Diuron and Fenitrothion, respectively. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. Underestimating advertising: innovation and unpriced entertainment

    OpenAIRE

    Leonard I. Nakamura

    2005-01-01

    Leonard Nakamura states that despite consumers’ lack of respect for advertising, it nonetheless plays a significant role in the economy. For one thing, it helps consumers find out about new products, and new products have been rising in economic importance. It also plays a role in subsidizing broadcast entertainment and news programs. Ultimately, Nakamura shows that although advertising contributes to consumer welfare, its contribution is missing from our measures of output.

  20. The Preliminary Study on Procurement Biliary Convergence from Donors with Complicated Bile Duct Variant in Emergency Right Lobe Living Donor Liver Transplantation.

    Science.gov (United States)

    Ye, Sheng; Dong, Jia-Hong; Duan, Wei-Dong; Ji, Wen-Bing; Liang, Yu-Rong

    2017-03-01

    The incidence of biliary complications after living donor adult liver transplantation (LDALT) is still high due to the bile duct variation and necessity reconstruction of multiple small bile ducts. The current surgical management of the biliary variants is unsatisfactory. We evaluated the role of a new surgical approach in a complicated hilar bile duct variant (Nakamura type IV and Nakamura type II) under emergent right lobe LDALT for high model for end-stage liver disease score patients. The common hepatic duct (CHD) and the left hepatic duct (LHD) of the donor were transected in a right-graft including short common trunks with right posterior and anterior bile ducts, whereas the LHD of the donor was anastomosed to the CHD and the common trunks of a right-graft bile duct and the recipient CHD was end-to-end anastomosed. Ten of 13 grafts (Nakamura types II, III, and IV) had two or more biliary orifices after right graft lobectomy; seven patients had biliary complications (53.8%). Later, the surgical innovation was carried out in five donors with variant bile duct (four Nakamura type IV and one type II), and, consequently, no biliary or other complications were observed in donors and recipients during 47-53 months of follow-up; significant differences ( P  ducts in a complicated donor bile duct variant may facilitate biliary reconstruction and reduce long-term biliary complications.

  1. Clonal and Widespread Gene Transfer by Proviral Electroporation for Analysis of Brain Laminar Formation

    Science.gov (United States)

    Sugiyama, Sayaka; Nakamura, Harukazu

    An essential approach to understanding the mechanisms of development is to alter a gene function/expression. In vivo electroporation has been adapted as one such technique (Muramatsu et al., 1997). It is a very useful tool to achieve a gain- and loss-of-function (by using RNAi or morpholinos) of a gene of interest (Funahashi et al., 1999; Fukuchi-Shimogori and Grove, 2001; Kos et al., 2001; Katahira and Nakamura, 2003; Sugiyama and Nakamura, 2003). The technique has allowed the altering of gene expression temporally and spatially. Pulse-labeling technique is an approach to manipulate a specific cell population temporally, depending on its birthday, as this chapter describes. This technique is more advantageous over the BrdU application, as it can reveal cell lineage; it also has the ability to manipulate a gain- and loss-of-function into specific precursor cells (Tabata and Nakajima, 2001; Sugiyama and Nakamura, 2003; Huber et al., 2008).

  2. Rietveld analysis system RIETAN (translation)

    International Nuclear Information System (INIS)

    Izumi, Fujio

    1991-09-01

    This is the manual of the RIETAN system (a Rietveld analysis program) which is originally written in Japanese by Fujio Izumi. The manual consists of two parts. Part I is a general description of the fundamental concepts and methods of the RIETAN system. Part II is the user's manual of the RIETAN which mainly describes in detail how to create user's data sets, procedures of Rietveld analysis and how to read the results of analysis. (author)

  3. Background story of the invention of efficient blue InGaN light emitting diodes

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Shuji [University of California, Santa Barbara, CA (United States)

    2015-06-15

    Shuji Nakamura discovered p-type doping in Gallium Nitride (GaN) and developed blue, green, and white InGaN based light emitting diodes (LEDs) and blue laser diodes (LDs). His inventions made possible energy efficient, solid-state lighting systems and enabled the next generation of optical storage. Together with Isamu Akasaki and Hiroshi Amano, he is one of the three recipients of the 2014 Nobel Prize in Physics. In his Nobel lecture, Shuji Nakamura gives an overview of this research and the story of his inventions. (copyright 2015 by WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  4. Accurate analysis of prevalence of coccidiosis in individually identified wild cranes in inhabiting and migrating populations in Japan.

    Science.gov (United States)

    Honma, Hajime; Suyama, Yoshihisa; Watanabe, Yuki; Matsumoto, Fumio; Nakai, Yutaka

    2011-11-01

    Eimeria gruis and E. reichenowi cause coccidiosis, a major parasitic disease of cranes. By non-invasive molecular approaches, we investigated the prevalence and genetic characterization of pathogens in two Japanese crane habitats; one is Hokkaido inhabited by the endangered red-crowned crane, and the other is Izumi in Kyushu where populations that consist mainly of vulnerable hooded and white-naped cranes migrate in winter. The non-invasively collected faecal samples from each wintering population were first subjected to host genomic DNA-targeted analyses to determine the sample origin and avoid sample redundancy. Extremely high prevalence was observed in the Izumi populations (> 90%) compared with the Hokkaido population (18-30%) by examining 470 specimens by microscopy and PCR-based capillary electrophoresis (PCR-CE), using genetic markers in the second internal transcribed spacer (ITS2). Correspondence analysis of PCR-CE data revealed differences in community composition of coccidia between hooded and white-naped cranes. 18S rRNA and ITS2 sequences were determined from single oocysts excreted by red-crowned and hooded cranes. Phylogenetic analysis of 18S rRNA suggested that E. reichenowi was polyphyletic while E. gruis was monophyletic. Together with PCR-CE data, these results indicate different host specificity among the E. reichenowi type. Our data suggest that E. reichenowi comprises multiple species. © 2011 Society for Applied Microbiology and Blackwell Publishing Ltd.

  5. Energy security strategy and nuclear power

    International Nuclear Information System (INIS)

    Toichi, Tsutomu; Shibata, Masaharu; Uchiyama, Yoji; Suzuki, Tatsujiro; Yamazaki, Kazuo

    2006-01-01

    This special edition of 'Energy security strategy and nuclear power' is abstracts of the 27 th Policy Recommendations 'The Establishment of an International Energy Security System' by the Japan Forum on International Relations, Inc on May 18 th , 2006. It consists of five papers: Energy security trend in the world and Japan strategy by Tsutomu Toichi, Establishment of energy strategy supporting Japan as the focus on energy security by Masaharu Shibata, World pays attention to Japan nuclear power policy and nuclear fuel cycle by Yoji Uchiyama, Part of nuclear power in the energy security - the basic approach and future problems by Tatsujiro Suzuki, and Drawing up the energy strategy focused on the national interests - a demand for the next government by Kazuo Yamazaki. (S.Y.)

  6. Nuclear signals in magnetically ordered media

    International Nuclear Information System (INIS)

    Ignatchenko, V.A.; Tsifrinovich, V.I.

    1993-01-01

    The book contains a review of theoretical and experimental investigations in the field of nuclear magnetism in magnetically ordered media. The semiclassical theory of nuclear spins motion is developed that takes into consideration three main features of magnetically ordered media: Suhl-Nakamura interaction, quadrupole interaction and microscopic inhomogeneity of nuclear frequencies. The detailed classification of nuclear spin echo signals is given for standard conditions of experiments, when the Suhl-Nakamura interaction is small in comparison with the NMR line width. The extremal states of the electron - nuclear magnetic system are described in detail: the coexistence of NMR and FMR, nuclear ferromagnetism and NMR at fast remagnetization of a ferromagnet. 157 refs., 20 figs

  7. 78 FR 68856 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2013-11-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Nakamura, Ph.D., Scientific Review Officer, Scientific Review Branch, National Human Genome Research...-402-0838. [[Page 68857

  8. Great Indoors Awards 2007

    Index Scriptorium Estoniae

    2007-01-01

    Hollandis Maastrichtis jagati 17. XI esimest korda rahvusvahelist auhinda The Great Indoors Award. Aasta sisekujundusfirmaks valiti Masamichi Katayama asutatud Wonderwall. Auhinna said veel Zaha Hadid, Heatherwick Studio, Ryui Nakamura Architects ja Item Idem

  9. Disease: H01471 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available HORS ... Ogita S, Tsuto T, Nakamura K, Deguchi E, Tokiwa K, Iwai N ... TITLE ... OK-432 therapy for lymphangioma in child...Rautio R, Rautiainen M, Airaksinen M ... TITLE ... OK-432 (Picibanil) therapy for lymphangiomas in children. ...

  10. Genetics Home Reference: Clouston syndrome

    Science.gov (United States)

    ... Nakamura M, Farooq M, Fujikawa H, Kibbi AG, Ito M, Dahdah M, Matta M, Diab H, Shimomura Y. GJB6, of which mutations underlie Clouston syndrome, is a potential direct target gene of p63. J Dermatol Sci. 2013 Feb; ...

  11. Stemcell Information: SKIP000172 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 12-03-417881 Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discove...ry Tanaka T, Takahashi K, Yamane M, Tomida S, Nakamura S, Oshima K, Niwa A, Nishiko

  12. 77 FR 60706 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-10-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research Institute Special.... Nakamura, Ph.D., Scientific Review Officer, Scientific Review Branch, National Human Genome Research...

  13. 75 FR 19984 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2010-04-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome..., National Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane, Suite 4075... Nakamura, PhD, Scientific Review Officer, Scientific Review Branch, National Human Genome Research...

  14. 76 FR 28056 - National Human Genome Research Institute; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-13

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... clearly unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research... D. Nakamura, PhD, Scientific Review Officer, Office of Scientific Review, National Human Genome...

  15. Author Details

    African Journals Online (AJOL)

    Pseudophilotes sinaicus Nakamura): an introduction. Abstract PDF · Vol 8 (2006) - Articles Interactions among species in a tri-trophic system: the influence of ants on the distribution of the Sinai Baton Blue butterfly. Abstract PDF · Vol 8 (2006) - ...

  16. Antimicrobial susceptibility of Escherichia coli isolated from feces of wild cranes migrating to Kagoshima, Japan.

    Science.gov (United States)

    Kitadai, Noriyuki; Obi, Takeshi; Yamashita, Shogo; Murase, Toshiyuki; Takase, Kozo

    2012-03-01

    Susceptibility to 13 antimicrobial agents was examined for 138 Escherichia coli isolates obtained from 192 fecal samples of wild cranes that migrated for wintering to the Izumi plain, Kagoshima prefecture in Japan. The numbers of isolates that were resistant to the antimicrobials used in this study are as follows: oxytetracycline (OTC), 22 isolates; minocycline, 7 isolates; ampicillin (ABPC), 4 isolates; nalidixic acid, 4 isolates; enrofloxacin, 2 isolates; kanamycin, one isolate. Multidrug resistant isolates exhibiting 2-4 drug resistances were obtained. All of the OTC-resistant isolates carried either the tet (A) or tet(B) gene. The bla(TEM) gene was found in all of the ABPC-resistant isolates.

  17. Keemia- ja füüsikapreemiate märksõna on valgus / Arko Olesk

    Index Scriptorium Estoniae

    Olesk, Arko, 1981-

    2014-01-01

    Nobeli keemiapreemia pälvisid sakslane Stefan Hell ning ameeriklased Eric Betzig ja William Moerner, kes leidsid viisi, kuidas uurida valgusmikroskoobiga eluslooduse pisimaid komponente. Füüsikapreemia pälvisid Jaapani teadlased Isamu Akasaki, Hiroshi Amano ja Shuji Nakamura sinise valgusdioodi leiutamise eest

  18. 75 FR 52538 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-08-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research Institute Special... Person: Ken D. Nakamura, PhD, Scientific Review Officer, Scientific Review Branch, National Human Genome...

  19. Fulltext PDF

    Indian Academy of Sciences (India)

    IAS Admin

    Isamu Akasaki, Meijo Univesity, Nagoya, Japan,. Nagoya University, Nagoya, Japan. Hiroshi Amano, Nagoya University, Nagoya, Japan. Shuji Nakamura, University of California, Santa Barbara, CA, USA. Chemistry. “for the development of super-resolved fluorescence microscopy” to. Eric Betzig, Janelia Research Campus ...

  20. Burn Rehabilitation and Research: Proceedings of a Consensus Summit

    Science.gov (United States)

    2009-08-01

    projectsperceivedasneeding investigation.Multicenter re- search initiatives are highly encouraged. ACKNOWLEDGMENTS We thank Carol Raymond, Maria Chapa, Travis...Engrav LH, Nakamura DY, Dutcher KA, Heimbach DM, Vedder NB. Treatment of fourth-degree hand burns. J Burn Care Rehabil 1995;16:36–42. 42. Mendez

  1. Mechanisms of Forming Intergranular Microcracks and Microscopic Surface Discontinuities in Welds

    Science.gov (United States)

    1992-06-01

    Nakamura, for their advice and assistance. To Steve Iwanowicz , my partner and friend, I extend my thanks for being there through it all and making it...Steve Iwanowicz [Twanowicz(1992)] 118 optical microscope. Therefore, in order to obtain the magnification of the displayed image, the objective lens

  2. Report on Symposium on Pacific Energy Cooperation 2001. Energy Security in Asian Region; Taiheiyo energy kyoryoku kaigi 2001 hokokusho. Asia chiiki no energy anzen hosho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-02-20

    The Symposium on Pacific Energy Cooperation (SPEC), which started in 1986 to discuss energy problems and international cooperation on energy in the Pacific region, met for 2001 in Tokyo on February 20 and 21, 2001, to discuss Energy Security in Asian Region. The conference comprised two keynote addresses, four sessions, and a panel discussion. Twenty-four countries and an international organization were represented by a total of 785 participants who actively exchanged views and opinions. With Director Tsutomu Toichi, The Institute of Energy Economics, Japan, acting as chairman, two keynote addresses were delivered. Minister of Oil Bijan Namdar Zanganeh of Iran reported on The Role of I. R. Iran in Meeting the Growing Oil and Gas Demand in the Asia-Pacific Region and Potential Cooperation with the Region's Consumers. Managing Director Phil Watts of the Royal Dutch/Shell Group reported on Security in Trust - Meeting Asian Energy Needs in the 21st Century. (NEDO)

  3. Some General Thoughts about Broken Symmetry.

    Science.gov (United States)

    1981-01-21

    Higgs boson excitations, the long-range elastic-like forces (such as Suhl-Nakamura interactions in magnets) but most important of all the property I call...parameter is also a constant of the motion, which has important consequences for the nature of the relevant Goldstone bosons . It is too bad that in

  4. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Abstract. In this note, we consider the Lifshitz singularity for Schrödinger operator with ergodic random magnetic field. A key estimate is an energy bound for magnetic Schrödinger operators as discussed in Nakamura [8]. Here we remove a technical assumption in [8], namely, the uniform boundedness of the magnetic field.

  5. Blowing-up semilinear wave equation with exponential nonlinearity ...

    Indian Academy of Sciences (India)

    H1-norm. Hence, it is legitimate to consider an exponential nonlinearity. Moreover, the choice of an exponential nonlinearity emerges from a possible control of solutions via a. Moser–Trudinger type inequality [1, 16, 19]. In fact, Nakamura and Ozawa [17] proved global well-posedness and scattering for small Cauchy data in ...

  6. A remark on the Lifshitz tail for Schrödinger operator with random ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    Abstract. In this note, we consider the Lifshitz singularity for Schrödinger opera- tor with ergodic random magnetic field. A key estimate is an energy bound for mag- netic Schrödinger operators as discussed in Nakamura [8]. Here we remove a technical assumption in [8], namely, the uniform boundedness of the magnetic ...

  7. CRS Issue Statement on State and Foreign Operations Appropriations

    Science.gov (United States)

    2010-01-12

    Moss Analyst in Global Health kmoss@crs.loc.gov, 7-7314 Melissa D. Ho Analyst in Agricultural Policy mho@crs.loc.gov, 7-5342 Kennon H. Nakamura...9525 Jim Nichol Specialist in Russian and Eurasian Affairs jnichol@crs.loc.gov, 7-2289 Charles E. Hanrahan Senior Specialist in Agricultural Policy chanrahan@crs.loc.gov, 7-7235 .

  8. Contribution to the study of nuclear resonance in magnetic media (1963); Contribution a l'etude de la resonance nucleaire dans les milieux magnetique (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Hartmann-Boutron, F [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1963-06-15

    An attempt is made to interpret the results of nuclear magnetic resonance experiments made by various workers on ferro and ferrimagnetic compounds of the iron group. The problems encountered are the following: effects of the dipolar fields and the hyperfine structure anisotropy; signal intensity; frequency pulling due to the Suhl-Nakamura interaction between nuclear spins ; nuclear relaxation and ferrimagnetic resonance in single domain samples of impure YIG; nuclear relaxation in the Bloch walls of insulators. The results of our calculations are generally in good agreement with experiment. (author) [French] On se propose d'interpreter les resultats d'experiences de resonance magnetique nucleaire fates par divers auteurs sur des composes ferro et ferrimagnetiques du groupe du fer. Les problemes abordes sont les suivants: effets des champs dipolaires et de l'anisotropie de structure hyperfine; intensite des signaux; deplacement de frequence du a l'interaction de Suhl-Nakamura entre spins nucleaires; relaxation nucleaire et resonance ferrimagnetique dans les echantillons monodomaines de grenat de fer et d'yttrium impur; relaxation nucleaire dans les parois de Bloch des isolants. Les resultats des calculs sont generalement en bon accord avec l'experience. (auteur)

  9. Contribution to the study of nuclear resonance in magnetic media (1963); Contribution a l'etude de la resonance nucleaire dans les milieux magnetique (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Hartmann-Boutron, F. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1963-06-15

    An attempt is made to interpret the results of nuclear magnetic resonance experiments made by various workers on ferro and ferrimagnetic compounds of the iron group. The problems encountered are the following: effects of the dipolar fields and the hyperfine structure anisotropy; signal intensity; frequency pulling due to the Suhl-Nakamura interaction between nuclear spins ; nuclear relaxation and ferrimagnetic resonance in single domain samples of impure YIG; nuclear relaxation in the Bloch walls of insulators. The results of our calculations are generally in good agreement with experiment. (author) [French] On se propose d'interpreter les resultats d'experiences de resonance magnetique nucleaire fates par divers auteurs sur des composes ferro et ferrimagnetiques du groupe du fer. Les problemes abordes sont les suivants: effets des champs dipolaires et de l'anisotropie de structure hyperfine; intensite des signaux; deplacement de frequence du a l'interaction de Suhl-Nakamura entre spins nucleaires; relaxation nucleaire et resonance ferrimagnetique dans les echantillons monodomaines de grenat de fer et d'yttrium impur; relaxation nucleaire dans les parois de Bloch des isolants. Les resultats des calculs sont generalement en bon accord avec l'experience. (auteur)

  10. Adaptive Immune Responses Regulate the Pathophysiology of Lymphedema

    Science.gov (United States)

    2012-09-01

    A, Hennig B (2000) Effect of complex decongestive physiotherapy on gene expression for the inflammatory response in peripheral lymphedema. Lymphology...pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma. Arthritis Rheum 63: 1405-1415. 51. Romani L, Mencacci A, Grohmann...severe disease in collagen-induced arthritis . Arthritis Rheum 48: 1452-1460. 29. Nakamura K, Radhakrishnan K, Wong YM, Rockson SG (2009) Anti

  11. On invariant MASAs for endomorphisms of the Cuntz algebras

    DEFF Research Database (Denmark)

    Hong, Jeong Hee; Skalski, Adam; Szymanski, Wojciech

    2010-01-01

    The problem of existence of standard (i.e. product-type) invariant MASAs for endomorphisms of the Cuntz algebras O_n is studied. In particular, endomorphisms which preserve the canonical diagonal MASA D_n are investigated. Conditions on a unitary w equivalent to the fact that the corresponding...... endomorphism λ_w preserves D_n are found, and it is shown that they may be satisfied by unitaries which do not normalize D_n. Unitaries giving rise to endomorphisms which leave all standard MASAs invariant and have identical actions on them are characterized. Finally, some properties of examples of finite......-index endomorphisms of O_n given by Izumi and related to sector theory are discussed and it is shown that they lead to an endomorphism of O_2 associated to a matrix unitary which does not preserve any standard MASA....

  12. Stemcell Information: SKIP000636 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available FGF ... 3% Negative ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学研究所バイオリソースセンター RI...KEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Available RIKEN BioResource Center 理化学

  13. Database Description - MicrobeDB.jp | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available tor Name: Yasukazu Nakamura Creator Affiliation: Center for Information Biology, National Institute of Genet...ics Journal Search: Creator Name: Ikuo Uchiyama Creator Affiliation: National Institute for Basic Biology Jo...urnal Search: Creator Name: Hiroshi Mori Creator Affiliation: Center for Information Biology...ion: Center for Information Biology, National Institute of Genetics Journal Search: Creator Name: Hirokazu C...hiba Creator Affiliation: National Institute for Basic Biology Journal Search: Cr

  14. Sisekujunduse maailmameistrid / Lylian Meister

    Index Scriptorium Estoniae

    Meister, Lylian, 1966-

    2008-01-01

    Hollandis 2007. a. novembris esmakordselt toimunud rahvusvahelisest sisearhitektuurikonkursist The Great Indoors Award. Aasta sisekujundusfirmaks valiti Masamichi Katayama asutatud Wonderwall. Ülejäänud auhinnad said Zaha Hadid Hispaanias asuva R.Lopez de Heredia veinidegusteerimise keskuse kujunduse eest, Heatherwick Studio East Beach Cafe kujunduse eest Inglismaal, Ryui Nakamura Architects Jins Global Standard prillipoe kontseptuaalse lahenduse eest Tokyos ja Item Idem Bernhard Willhelmi moebrändi esindusbutiigi kujunduse eest Tokyos

  15. Energy Harvesting for Self-Powered, Ultra-Low Power Microsystems With a Focus on Vibration-Based Electromechanical Conversion

    Science.gov (United States)

    2009-09-01

    capacitor responsible for charge. Figure 25. Half Bridge Power Harvester with Leakage Resistance [From 70] The resistor accounts for the voltage...REV PAP, 1996. [63] M. Umeda, K. Nakamura, and S. Ueha, “Energy storage characteristics of a piezo - generator using impact induced vibration...Japanese journal of applied physics, vol. 36, pp. 3146–3151, 1997. [64] M. Kimura, “ Piezo -electricity generation device,” U.S. Patent 812070, September

  16. Application of 1D Array FBG Configuration for Impact Localization on Composite Wing under Simulated Noise

    Science.gov (United States)

    2016-03-30

    Nakamura et al., implemented a FBG/ PZT hybrid sensor system for impact monitoring of aircraft composite structure [9]. FBG sensor was shown to be...is the coefficient of thermal expansion,  is the thermal-optic coefficient , T is the temperature,  is the strain value, and ep is the photo...localization algorithm is used to localize the impact points. In the correlation based impact localization algorithm, the correlation coefficient between the

  17. Incidence of dizziness and vertigo in Japanese primary care clinic patients with lifestyle-related diseases: an observational study

    OpenAIRE

    Wada, Masaoki; Takeshima,Taro; Nakamura,Yosikazu; Nagasaka,Shoichiro; Kamesaki,Toyomi; Oki,Hiroshi; Kajii,Eiji

    2015-01-01

    Masaoki Wada,1,2 Taro Takeshima,1 Yosikazu Nakamura,3 Shoichiro Nagasaka,4 Toyomi Kamesaki,1 Hiroshi Oki,2 Eiji Kajii1 1Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University, Tochigi, Japan; 2Oki Clinic, Ibaraki, Japan; 3Department of Public Health, Jichi Medical University, Tochigi, Japan; 4Department of Internal Medicine, Division of Endocrinology and Metabolism, Jichi Medical University, Tochigi, Japan Objective: Dizziness and vertigo are highl...

  18. Stemcell Information: SKIP000646 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available ing and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学研究所バイオリ...ソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information Only RIKEN BioResource Center 理化学

  19. High-Order Hyperbolic Residual-Distribution Schemes on Arbitrary Triangular Grids

    Science.gov (United States)

    2015-06-22

    for efficient CFD calculations in high-order methods,3 because the grid adaptation almost necessarily introduces irregularity in the grid. In fact...problems. References 1P.A. Gnoffo. Multi-dimensional, inviscid flux reconstruction for simulation of hypersonic heating on tetrahedral grids. In Proc. of...Kitamura, E. Shima, Y. Nakamura, and P.L. Roe. Evaluation of euler fluxes for hypersonic heating computations. AIAA J., 48(4):763–776, 2010. 3Z.J. Wang, K

  20. Dongfeng has fixed a sales goal of 80 billion yuan supported by Nissan

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    <正> The Nissan and Dongfeng Group-based Dongfeng Automobile Co., Ltd, which has the largest investment in the history of the industry, opened officially for business on July 1. With a total investment of USD 2 billion and 70,000 employees, the company is the first joint venture in China which plans a full range of truck, light commercial and passenger vehicles. According to president Nakamura, the company has established a management

  1. Comment on "Active sites for CO2 hydrogenation to methanol on Cu/ZnO catalysts"

    DEFF Research Database (Denmark)

    Nakamura, Junji; Fujitani, Tadahiro; Kuld, Sebastian

    2017-01-01

    Kattel et al (Reports, 24 March 2017, p. 1296) report that a zinc on copper (Zn/Cu) surface undergoes oxidation to zinc oxide/copper (ZnO/Cu) during carbon dioxide (CO2) hydrogenation to methanol and conclude that the Cu-ZnO interface is the active site for methanol synthesis. Similar experiments...... conducted two decades ago by Fujitani and Nakamura et al demonstrated that Zn is attached to formate rather than being fully oxidized....

  2. Vacuum vessel for plasma devices

    International Nuclear Information System (INIS)

    Yamada, Masao; Taguchi, Masami.

    1975-01-01

    Object: To permit effective utility of the space in the inner and outer sides of the container wall and also permit repeated assembly for use. Structure: Vacuum vessel wall sections are sealed together by means of welding bellows, and also flange portions formed at the end of the wall sections are coupled together by bolts and are sealed together with a seal ring and a seal cap secured by welding. (Nakamura, S.)

  3. Plant maintenance and advanced reactors issue, 2008

    Energy Technology Data Exchange (ETDEWEB)

    Agnihotri, Newal [ed.

    2009-09-15

    The focus of the September-October issue is on plant maintenance and advanced reactors. Major articles/reports in this issue include: Technologies of national importance, by Tsutomu Ohkubo, Japan Atomic Energy Agency, Japan; Modeling and simulation advances brighten future nuclear power, by Hussein Khalil, Argonne National Laboratory, Energy and desalination projects, by Ratan Kumar Sinha, Bhabha Atomic Research Centre, India; A plant with simplified design, by John Higgins, GE Hitachi Nuclear Energy; A forward thinking design, by Ray Ganthner, AREVA; A passively safe design, by Ed Cummins, Westinghouse Electric Company; A market-ready design, by Ken Petrunik, Atomic Energy of Canada Limited, Canada; Generation IV Advanced Nuclear Energy Systems, by Jacques Bouchard, French Commissariat a l'Energie Atomique, France, and Ralph Bennett, Idaho National Laboratory; Innovative reactor designs, a report by IAEA, Vienna, Austria; Guidance for new vendors, by John Nakoski, U.S. Nuclear Regulatory Commission; Road map for future energy, by John Cleveland, International Atomic Energy Agency, Vienna, Austria; and, Vermont's largest source of electricity, by Tyler Lamberts, Entergy Nuclear Operations, Inc. The Industry Innovation article is titled Intelligent monitoring technology, by Chris Demars, Exelon Nuclear.

  4. Causality and hyperbolicity of Lovelock theories

    International Nuclear Information System (INIS)

    Reall, Harvey S; Tanahashi, Norihiro; Way, Benson

    2014-01-01

    In Lovelock theories, gravity can travel faster or slower than light. The causal structure is determined by the characteristic hypersurfaces. We generalize a recent result of Izumi to prove that any Killing horizon is a characteristic hypersurface for all gravitational degrees of freedom of a Lovelock theory. Hence gravitational signals cannot escape from the region inside such a horizon. We investigate the hyperbolicity of Lovelock theories by determining the characteristic hypersurfaces for various backgrounds. First we consider Ricci flat type N spacetimes. We show that characteristic hypersurfaces are generically all non-null and that Lovelock theories are hyperbolic in any such spacetime. Next we consider static, maximally symmetric black hole solutions of Lovelock theories. Again, characteristic surfaces are generically non-null. For some small black holes, hyperbolicity is violated near the horizon. This implies that the stability of such black holes is not a well-posed problem. (paper)

  5. External magnetic field induced anomalies of spin nuclear dynamics in thin antiferromagnetic films

    International Nuclear Information System (INIS)

    Tarasenko, S.V.

    1995-01-01

    It is shown that if the thickness of homogeneously magnetized plate of high-axial antiferromagnetic within H external magnetic field becomes lower the critical one, then the effect of dynamic magnetoelastic interaction on Soul-Nakamura exchange of nuclear spins results in formation of qualitatively new types of spreading nuclear spin waves no else compared neither within the model of unrestricted magnetic nor at H = 0 in case of thin plate of high-axial antiferromagnetic. 10 refs

  6. Military Vision Research Program. Addendum

    Science.gov (United States)

    2011-08-01

    Vis Sci. 52(9):6174-6180. 4. Zoukhri, D. 2006. Effect of inflammation on lacrimal gland function . Exp Eye Res. 82(5):885-898. 5. Nakamura, S., M...GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER E-Mail: 5f. WORK UNIT NUMBER 7. PERFORMING...NOMID), and they are collectively referred to as the cryopyrin/NALP3- associated periodic syndromes (CAPS). Functional studies revealed that the

  7. Fast-forward of quantum adiabatic dynamics in electro-magnetic field

    OpenAIRE

    Masuda, Shumpei; Nakamura, Katsuhiro

    2010-01-01

    We show a method to accelerate quantum adiabatic dynamics of wavefunctions under electro-magnetic field by developing the previous theory (Masuda & Nakamura 2008 and 2010). Firstly we investigate the orbital dynamics of a charged particle. We derive the driving field which accelerates quantum adiabatic dynamics in order to obtain the final adiabatic states except for the spatially uniform phase such as the adiabatic phase in any desired short time. Fast-forward of adiabatic squeezing and tran...

  8. In Situ Detection, Isolation, and Physiological Properties of a Thin Filamentous Microorganism Abundant in Methanogenic Granular Sludges: a Novel Isolate Affiliated with a Clone Cluster, the Green Non-Sulfur Bacteria, Subdivision I

    OpenAIRE

    Sekiguchi, Yuji; Takahashi, Hiroki; Kamagata, Yoichi; Ohashi, Akiyoshi; Harada, Hideki

    2001-01-01

    We previously showed that very thin filamentous bacteria affiliated with the division green non-sulfur bacteria were abundant in the outermost layer of thermophilic methanogenic sludge granules fed with sucrose and several low-molecular-weight fatty acids (Y. Sekiguchi, Y. Kamagata, K. Nakamura, A. Ohashi, H. Harada, Appl. Environ. Microbiol. 65:1280–1288, 1999). Further 16S ribosomal DNA (rDNA) cloning-based analysis revealed that the microbes were classified within a unique clade, green non...

  9. Determination of NEHRP Site Class of Seismic Recording Stations in the Northwest Himalayas and Its Adjoining Area Using HVSR Method

    Science.gov (United States)

    Harinarayan, N. H.; Kumar, Abhishek

    2018-01-01

    Local site characteristics play an important role in controlling the damage pattern during earthquakes (EQs). These site characteristics may vary from simple to complex and can be estimated by various field tests. In addition, extended Nakamura's method, which uses horizontal to vertical spectral ratio (HVSR) based on available EQ records also available for site class (SC) determination. In this study, SCs for 90 recording stations which are maintained by Program for Excellence in Strong Motion Studies (PESMOS), located in the northwestern Himalayas and the adjoining areas are determined using extended Nakamura's technique. Average HVSR curves obtained at majority of the recording stations are found matching with the existing literature. Predominant frequency ( f peak) from average HVSR curve at each recording station is then used for the determination of SC. Original SC given by PESMOS is purely based on geology and not based on comprehensive soil investigation exercise. In this study, the SC, which is based on the average HVSR curves is found matching with SC given by PESMOS for a majority of recording stations. However, for considerable number of recording stations, a mismatch is also found which is consistent with the existing literature. In addition, SC based on National Earthquake Hazard Reduction Program (NEHRP) scheme is proposed based on f peak for all the 90 recording stations.

  10. Protective Role of Angiogenin Against Hematopoietic Syndrome of the Acute Radiation Syndrome

    Science.gov (United States)

    2017-05-01

    aged-animal experiments, 22-month-old WT (NIH/ NIA [National Institute on Aging]) and Ang/ mice were used. For all other studies, age-matched 7- to...with cell sorting and Dr. Alenka Lovy for assistance with microscopy. Aged WT mice were kindly provided by NIH/ NIA , andOsx andOcn cDNAwere gifts kindly...Scadden, D.T. (2014). The bone marrow niche for haema- topoietic stem cells. Nature 505 , 327–334. Nakamura-Ishizu, A., Takizawa, H., and Suda, T. (2014

  11. Development of a novel disposable lid speculum with a drape

    OpenAIRE

    Urano, Toru; Kasaoka, Masataka; Yamakawa, Ryoji; YukihikoTamai,; Nakamura, Shoichiro

    2013-01-01

    Toru Urano,1 Masataka Kasaoka,1 Ryoji Yamakawa,1 YukihikoTamai,2 Shoichiro Nakamura21Department of Ophthalmology, Kurume University School of Medicine, Kurume, Japan; 2Hakko Co, Ltd, Nagano, JapanPurpose: To evaluate the clinical use of a newly-developed disposable lid speculum with a drape.Methods: LiDrape® is a cylindrical device that consists of two flexible rings of polyacetal resin with a transparent elastic silicone sheet attached to the rings. The novel device holds the eyelids...

  12. Stemcell Information: SKIP000654 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available ujioka 藤岡 剛 RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Naka...mura 中村　幸夫 Information Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973

  13. Stemcell Information: SKIP000649 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available Fujioka 藤岡 剛 RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Na...kamura 中村　幸夫 Information Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 209

  14. Stemcell Information: SKIP000651 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available ujioka 藤岡 剛 RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Naka...mura 中村　幸夫 Information Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973

  15. The Installation Restoration Program Toxicology Guide. Volume 3

    Science.gov (United States)

    1989-07-01

    Cannon, C.; Bloom , A.D.; Nakamu~ra, F.; Ahmned, M.; Duk, S.; Rimpo, J.; Margolin, B~a; Resnickr. M.A; Anderson, B.; Zeiger, E. 1987. Chromosome...carbon compounds evaluated in the SCE test in vitro. Environ Mutage:. 9.401-410. 3846. Woodruff, R.& ; Mason, J.M.; Valencia , RL; Zi7nmering, S. 1984...0.2 ppm), bread, oranges and rum. This compound appears to be a r.ommon component of the diet although a total exposure from this source can not be

  16. Magnesium Aluminum Borides as Explosive Materials

    Science.gov (United States)

    2011-12-20

    pestle and screened -325 mesh to remove the filter paper. However, some of the filter paper remained in this powder. Table 13 Compositions of...Property of Si-B System Ceramics,” J. Japan Soc. Pow. and Pow. Met., 41[11] 1299-1303 (1994). 53. H. Nakamura, K. Murata, T. Anan, and Y. Hara...Oxidation of Zirconium Borides,” J. Japan Explosives Society, 55[4] 142-146 (1994). 54. M. Woerle, R.Nesper, G. Mair, M. Schwarz, and H. G. von Schnering

  17. Wind power for the world international reviews and developments

    CERN Document Server

    Maegaard, Preben; Palz, Wolfgang

    2013-01-01

    Introduction, Preben MaegaardAccelerated Global Expansion of the Renewable Energy Sector: the Example of Wind Energy, Preben MaegaardWind Power Development in the European Union, Wolfgang PalzWind Energy to the rescue of mankind from the menace of the Fossil Fuel burning hazards, Anil KaneBlack or Green Wind Power, Frede HvelplundWind Energy Development in China, He DexinNon-grid-connected Wind Power and Offshore "Three Georges of Wind Power" in China, Gu WeidongWind Power in Japan: Past, Present, and Future Prospect, Izumi UshiyamaWind Power Development in India, Jami HossainChallenges and Opportunities for Energy Paradigm Shifting in Ontario, Canada, Jose EtcheverryWind Power in Cuba's Energy Revolution, Conrado Moreno FigueredoWind Power in Argentina, Erico SpinadelThe Emergence of Wind Power in Brazil, Everaldo FeitosaWind Energy in Chile, Arturo KunstmannWind Power in Austria, Wolfgang HeinThe History of Wind Power in France, Jean-Louis BalHistory, State-of-the Art and Future of Wind Energy in France, Ma...

  18. Identificación del agente causal de la antracnosis de Sansevieria spp. en Costa Rica

    OpenAIRE

    Pérez-León, Gerardo; Chavarría-Pérez, Lourdes; Araya-Quesada, Julio; Gómez-Alpízar, Luis

    2013-01-01

    Sansevieria spp. (Agavaceae) es una ornamental de follaje originaria de África y Asia. S. trifasciata (St) es la especie con mayor número de cultivares en el mercado de exportación de Costa Rica a Estados Unidos y Holanda. Muestras foliares de S. trifasciata var. “Hahnii” con lesiones circulares y acuosas (algunas alargadas y secas), fueron analizadas. El patógeno recuperado fue identificado como Colletotrichum sansevieriae Nakamura (CsN) mediante pruebas de patogenicidad, morfología y técnic...

  19. Reactor feedwater system

    International Nuclear Information System (INIS)

    Hikabe, Katsumi.

    1978-01-01

    Purpose: In order to prevent thermal stresses of a core of PWR type reactor, described has been a method for feeding heated recirculating water to the core in the case of the reactor start-up or shut-down. Constitution: A recirculating water is degassed, cleaned up and heated in the steam condensers, and then feeds the water to the reactor, characterized in that heaters are provided in the bypasses of the turbine, so that heated water is constantly supplied to the reactor. (Nakamura, S.)

  20. Making sense of the Sense Model: translation priming with Japanese-English bilinguals

    OpenAIRE

    Allen, David; Conklin, Kathy; Van Heuven, Walter J.B.

    2015-01-01

    Many studies have reported that first language (L1) translation primes speed responses to second language (L2) targets, whereas L2 translation primes generally do not speed up responses to L1 targets in lexical decision. According to the Sense Model (Finkbeiner, Forster, Nicol & Nakamura, 2004) this asymmetry is due to the proportion of senses activated by the prime. Because L2 primes activate only a subset of the L1 translations senses, priming is not observed. In this study we test the pred...

  1. Stemcell Information: SKIP000278 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available man bFGF ... Negative ... Yes ... Natsumi Shimizu 清水　なつみ RIKEN BioResource Center 理化学研究所バイオリソースセンタ...ー RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Available--Avai...lable--Available RIKEN BioResource Center--Makoto Yazaki(Nagoya City University)--iPS Academia Japan,Inc. 理化学

  2. ROUND-ROBIN ATOM-PROBE EXPERIMENT : PRELIMINARY RESULTS IN JAPAN

    OpenAIRE

    Nakamura , S.

    1986-01-01

    A round-robin experiment were to be carried out by 6 laboratories in Japan (Nishikawa ; Tokyo Inst. Tech., Sakurai and Igata ; Univ. of Tokyo, Ishikawa ; Hitachi, Tanino ; Nippon Steel Corp. and Nakamura ; Osaka Univ.) under the normal operating condition (T < l00 °K,. pulse fraction ~ 15% ~, P < 10-9 torr). Fe-Cr-Al and W-25%Re alloys, which are divided from a single wire were chosen as the specimen materials. A preliminary analysis of the W-Re alloy of the laboratory concerned show the good...

  3. 23RD International Conference on Phenomena in Ionized Gases, Volume 1

    Science.gov (United States)

    1998-12-01

    PLASMAS 1-76 Ohe K., Kimura T., Nakamura M. IONIZATION COEFFICIENT IN ARGON-ISOBUTANE MIXTURES 1-78 Krajcar-Bronic I., Grosswendt B. ON THE INFLUENCE OF...Tanaka, Xiaodong Zheng, Kazuo Minami, Takao Nagahama and Hisashi Tokurnasu Graduate School of Science and Technology, Niigata Univerity, Niigata 950...S.V. III-54 Krenek P. 11-104 Jelenkovic B.M. 1-98 HII-56 Kriha V. 1-266 Jivotov V.K. IV-222 Kimura T. 1-76 Kroesen G.M.W. 1-152 IV-224 11-22 IV.246

  4. A Partnership Training Program: Studying Targeted Drug Delivery Using Nanoparticles In Breast Cancer Diagnosis and Therapy

    Science.gov (United States)

    2011-10-01

    and chemical synthesis,” Acta Physica Polonica A, vol. 113, no. 1, pp. 573–576, 2008. [34] R. Hergt, R. Hiergeist, M. Zeisberger et al., “Magnetic... Physica B, vol. 350, no. 1–3, pp. E309– E313, 2004. [18] Y. A. Gorby, T. J. Beveridge, and R. P. Blakemore, “Character- ization of the bacterial...N. Nakamura and T.Matsunaga, “Highly sensitive detection of allergen using bacterial magnetic particles,” Analytica Chimica Acta , vol. 281, no. 3, pp

  5. ITER EDA newsletter. V. 8, no. 6

    International Nuclear Information System (INIS)

    1999-06-01

    A ceremony was held on 1 June 1999 at the Naka Fusion Research Establishment of JAERI to celebrate the successful development and fabrication of the ITER Central Solenoid Model Coil Inner Module and Outer Module and the CS Insert Coil. At this occasion, Dr. Martha Krebs from the US-DOE regretted the withdrawal of the United States from the ITER project, the US are now looking for Japan, the European Union and the Russian Federation to continue making progress. In response to this speech, Mr. Tsutomu Imamura said, that that was to be regretted and stated that Japan actively promoted the ITER project. Then, Dr. Michel Huguet, representing the JCT, presented a message from Dr. R. Aymar, the director of the ITER program. In this message he indicated that each and every one who had been involved in that project could take great pride. The ceremony was concluded by warm and thoughtful words from Dr. Masami Fujiwara and a toast by Dr. Masaji Yoshikawa. At the end, all participants praised each other for their efforts and the three coils, the CS Model Coil Inner Module, the Outer Module and the the CS Insert Coil, seemed to be smiling at them

  6. Groundwater recharge and agricultural contamination in alluvial fan of Eastern Kofu basin, JAPAN

    Science.gov (United States)

    Nakamura, T.

    2009-12-01

    Agriculture has significant effects on the rate and composition of groundwater recharge. The chemical loading into groundwater have been dominated by the constituents derived directly or indirectly from agricultural practices and additives. The contamination of groundwater with nitrate is a major public health and environmental concern around the world. The inorganic constituents like, K+, Ca2+, Mg2+, SO42-, Cl- and variety of other minor elements of groundwater are often used as agricultural additives; and the natural occurrence of these elements are dominated by the agricultural sources. A recent study has reported that Kofu basin groundwater aquifer is contaminated by nitrate from agricultural areas because of the fertilizer application for the orchard (Kazama and Yoneyama, 2002; Sakamoto et al., 1997, Nakamura et al., 2007). The water-oxygen and hydrogen stable isotope (δ18O and δD) and nitrate-nitrogen stable isotope (δ15N) of groundwater, river water and precipitation samples were investigated to identify the source of groundwater and nitrate nitrogen contamination in groundwater in the Fuefukigawa and Hikawa_Kanegawa alluvial fans in Kofu basin. The plot of δD versus δ18O values of groundwater, river water and precipitation samples suggest that the groundwater is a mixture of precipitation and river water. And nitrate-nitrogen isotope values have suggested the nitrate contamination of groundwater is from agricultural area. The study revealed positive correlation between groundwater δ18O values and NO3-, Cl-, SO42-, Ca2+, Mg2+ concentration, which shows the agricultural contamination is carried by the recharge of groundwater from precipitation in alluvial fan. Whereas, NO3-, Cl-, SO42-, Ca2+, Mg2+ are diluted by the river water recharges. This study showed the quality of groundwater is resulted from the mixing of water from the different source during the groundwater recharge in the study area. References Kazama F, Yoneyama M (2002) Nitrogen generation

  7. A Note on the Seven Bridges of Königsberg Problem

    Directory of Open Access Journals (Sweden)

    Naumowicz Adam

    2015-02-01

    Full Text Available In this paper we account for the formalization of the seven bridges of Königsberg puzzle. The problem originally posed and solved by Euler in 1735 is historically notable for having laid the foundations of graph theory, cf. [7]. Our formalization utilizes a simple set-theoretical graph representation with four distinct sets for the graph’s vertices and another seven sets that represent the edges (bridges. The work appends the article by Nakamura and Rudnicki [10] by introducing the classic example of a graph that does not contain an Eulerian path.

  8. Autocorrelation in queuing network type production systems - revisited

    DEFF Research Database (Denmark)

    Nielsen, Erland Hejn

    -production systems (Takahashi and Nakamura, 1998) establishes that autocorrelation plays definitely a non-negligible role in relation to the dimensioning as well as functioning of Kanban-controlled production flow lines . This must logically either imply that production managers are missing an important aspect...... in their production planning reasoning, or that the 'realistic' autocorrelation patterns , inherent in actual production setups , are not like those so far considered in the literature. In this paper, an attempt to characterise relevant and 'realistic' types of autocorrelation schemes as well as their levels...

  9. Stemcell Information: SKIP000661 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

  10. Stemcell Information: SKIP000643 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available kaline phosphatase staining and immunocytochemistry ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information On...ly RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-0774.2

  11. Stemcell Information: SKIP000641 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available Alkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Informati...on Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-0

  12. Stemcell Information: SKIP000220 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 0.1mM 2-Mercaptoethanol+5ng/mL human bFGF ... Yes 46XX(18), 47XX+X(2) ... Tsuyoshi Fujioka 藤岡　剛 RIKEN BRC 理化学...研究所バイオリソースセンター RIKEN BRC 理化学研究所バイオリソースセンター Yukio Nakamura 中村幸夫 Available RIKEN BRC 理化学研究所バイオリ

  13. Stemcell Information: SKIP000657 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

  14. Stemcell Information: SKIP000658 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

  15. Stemcell Information: SKIP000659 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

  16. Stemcell Information: SKIP000642 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available kaline phosphatase staining and immunocytochemistry ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information On...ly RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-0774.2

  17. Stemcell Information: SKIP000660 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

  18. Stemcell Information: SKIP000650 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

  19. Stemcell Information: SKIP000656 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

  20. Stemcell Information: SKIP000645 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available kaline phosphatase staining and immunocytochemistry ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information On...ly RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-0774.2

  1. Stemcell Information: SKIP000647 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available staining and immunocytochemistry ... Yes Teratoma formation ... Yes ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Informat...ion Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-

  2. Stemcell Information: SKIP000638 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available Alkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Informati...on Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-0

  3. Siegert pseudostate formulation of scattering theory: Nonzero angular momenta in the one-channel case

    International Nuclear Information System (INIS)

    Batishchev, Pavel A.; Tolstikhin, Oleg I.

    2007-01-01

    The Siegert pseudostate (SPS) formulation of scattering theory, originally developed by Tolstikhin, Ostrovsky, and Nakamura [Phys. Rev. A, 58, 2077 (1998)] for s-wave scattering in a spherically symmetric finite-range potential, is generalized to nonzero angular momenta. The orthogonality and completeness properties of SPSs are established and SPS expansions for the outgoing-wave Green's function, physical states, and scattering matrix are obtained. The present formulation completes the theory of SPSs in the one-channel case, making its application to three-dimensional problems possible. The results are illustrated by calculations for several model potentials

  4. Optical Spectroscopy of TCP J04432130+4721280 (V392 Per) Confirms a Nova Eruption

    Science.gov (United States)

    Wagner, R. M.; Terndrup, D.; Darnley, M. J.; Starrfield, S.; Woodward, C. E.; Henze, M.

    2018-04-01

    Following reports of a new transient of magnitude 6.2 in Perseus on 2018 April 29.4740 UT discovered by Y. Nakamura designated TCP J04432130+4721280 (http://www.cbat.eps.harvard.edu/unconf/followups/J04432130+4721280.html) and positionally coincident with the previously known U Gem type dwarf nova V392 Per, we obtained an optical spectrum on 2018 April 30.116 UT (range: 396-687 nm; resolution 0.3 nm) with the 2.4 m Hiltner telescope (+OSMOS) of the MDM Observatory on Kitt Peak.

  5. Contribution to the study of nuclear resonance in magnetic media (1963)

    International Nuclear Information System (INIS)

    Hartmann-Boutron, F.

    1963-06-01

    An attempt is made to interpret the results of nuclear magnetic resonance experiments made by various workers on ferro and ferrimagnetic compounds of the iron group. The problems encountered are the following: effects of the dipolar fields and the hyperfine structure anisotropy; signal intensity; frequency pulling due to the Suhl-Nakamura interaction between nuclear spins ; nuclear relaxation and ferrimagnetic resonance in single domain samples of impure YIG; nuclear relaxation in the Bloch walls of insulators. The results of our calculations are generally in good agreement with experiment. (author) [fr

  6. PREFACE: 3rd International Workshop on Materials Analysis and Processing in Magnetic Fields (MAP3)

    Science.gov (United States)

    Sakka, Yoshio; Hirota, Noriyuki; Horii, Shigeru; Ando, Tsutomu

    2009-07-01

    the journal Science and Technology of Advanced Materials. All articles have been refereed by experts in the field. Both of these journals are fully accessible electronically and can be cited and referenced in the usual way. It is our hope that the reader will enjoy and profit from the MAP3 Proceedings. Hitoshi Wada (Kashiwa, Japan) Chair Eric Beaugon (Grenoble, France) Hans J Schneider-Muntau (Tallahassee, USA) Co-chair Advisory Board Shigeo Asai (Nagoya, Japan) Koichi Kitazawa (Tokyo, Japan) Mitsuhiro Motokawa (Sendai, Japan) Shoogo Ueno (Fukuoka, Japan) Robert Tournier (Grenoble, France) Justin Schwartz (Tallahassee, USA) J C Maan (Nijmegen, Netherland) Scientific Committee Yoshifumi Tanimoto (Hiroshima, Japan) Masuhiro Yamaguchi (Yokohama, Japan) Tsunehisa Kimura (Kyoto, Japan) Yoshio Sakka (Tsukuba Japan) Ryoichi Aogaki (Tokyo, Japan) Jyunji Miyakoshi (Hirosaki, Japan) Kazuo Watanabe (Sendai, Japan) James M Valles Jr. (Providence, USA) Joon Pyo Park (Pohang, Korea) Qiang Wang (Shenyang, China) Nicole Pamme (Hull, UK) Sophie Rivoirard (Grenoble, France) P C M Christianen (Nijmegen, Netherland) Local Organizing Committee Isao Yamamoto Masafumi Yamato Shigeru Horii Norihito Sogoshi Masateru Ikehata Noriyuki Hirota Tsutomu Ando Proceedings Editorial Board Yoshio Sakka Noriyuki Hirota Shigeru Horii Tsutomu Ando Conference photograph

  7. FY 2000 report on the results of the joint research - Field test project on the photovoltaic power generation for public facility use; 2000 nendo kyodokenkyu gyomu seika hokokusho. Kokyo shisetsu you taiyoko hatsuden field test jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-05-01

    The paper arranged the FY 2000 results of the field test on the photovoltaic power generation for public facility use, etc. This report described in detail the results obtained at 237 places including the following: Social Welfare Corp. Seimei-kai, Kobe City (Hyogo Prefecture), Iitaka Town of Iinan County (Mie Prefecture), Kyushu Electric Safety Association, Educational Corp. Kongo Gakuen, Social Welfare Corp. Izumi-kai, Educational Corp. Shiobara Ikuei-kai, Educational Corp. Aiko Gakuen, Social Welfare Corp. Tachibana-kai, Cooperative Association Co-op Kobe, Social Welfare Corp. Hoshizuki-no-sato, Tochigi-Fuji Industrial Co., Hirabayashi Section of Gamo Town of Gamo County (Shiga Prefecture), Yanagawa City (Fukuoka Prefecture), Imadate City of Imadate County (Fukui Prefecture), Osaka Prefecture, Yamanashi Prefecture, Utazu Town of Ayauta County (Kagawa Prefecture), Educational Corp. Fukuyama Gakuen, New Energy Business Cooperative Association, Meitec Corp., Shikoku Medicom Co., Shizen Kobo Co., Educational Corp. Horikoshi Gakuen, Matama Town of Nishi-Kunisaki County (Oita Prefecture), Nio Town of Mitoyo County (Kagawa Prefecture), Educational Corp. Koshien Gakuin, Sansei Giken Co., Mitsui Greenland Co., AWI Mach Co., Nagoya City and Educational Corp. Kibogaoka Gakuen. (NEDO)

  8. Strainer device

    International Nuclear Information System (INIS)

    Mokuya, Kenji.

    1975-01-01

    Object: To provide a strainer device, which is adapted to facilitate flushing and is particularly suited for installation in the cooling system of a liquid metal cooled fast breeding reactor. Structure: A casing accommodating a strainer and a blind plate for the selection of a flow path is provided at a suitable portion of the duct line. The blind plate is adapted to be rotated by an opening and closing means consisting of a rod. bellows, shaft and so forth. At the time of flushing, the duct line is sealed by the blind plate. (Nakamura, S.)

  9. Erosion of a wet/dry granular interface

    Science.gov (United States)

    Jop, Pierre; Lefebvre, Gautier

    2013-04-01

    To model the dynamic of landslides, the evolution of the interface between the erodible ground and the flowing material is still studied experimentally or numerically (ie. Mangeney et al. 2010, Iverson 2012). In some cases, the basal material is more cohesive than the flowing one. Such situation arises for example due to cementation or humidity. What are the exchange rates between these phases? What is the coupling between the evolution of the interface and the flow? We studied the erosion phenomenon and performed laboratory experiments to focus on the interaction between a cohesive unsaturated granular material and a dry granular flow. Both materials were spherical grains, the cohesion being induced by adding a given mass of liquid to the grains. Two configurations were explored: a circular aggregate submitted to a dry flow in a rotating drum, and a granular flow eroding a wet granular pile. First, we focused on the influence of the cohesion, controlled by the liquid properties, such as the surface tension and the viscosity. Then the flow characteristics were modified by varying the grain size and density. These results allowed us to present a model for the erosion mechanisms, based on the flow and fluid properties. The main results are the need to take into account the whole probability distribution the stress applied on the wet grains and that both the surface tension and the viscosity are important since they play a different roles. The latter is mainly responsible of the time scale of the dynamic of a wet grain, while the former acts as a threshold on the force distribution. In the second configuration, we could also control the inclination of the slope. This system supported the previous model and moreover revealed an interface instability, leading the formation of steep steps, which is a reminiscence of the cyclic-steps observed during river-channel incision (Parker and Izumi 2000). We will present the dynamics of such granular steps. [1] Mangeney, A., O

  10. List of participants at SIDE IV meeting, Tokyo, 27 November--1 December 2000

    Science.gov (United States)

    2001-12-01

    Mark J Ablowitz, Vsevolod Adler, Mark Alber, Said Belmehdi, Marco Boiti, Claude Brezinski, R Bullough, Y M Chiang, Theodore Chihara, Peter A Clarkson, Robert Conte, Adam Doliwa, Vladimir Dorodnitsyn, Mitsuaki Eguchi, Claire Gilson, Basil Grammaticos, Valeri Gromak, Rod Halburd, Koji Hasegawa, Jarmo Hietarinta, Ryogo Hirota, Xing Biao Hu, M Idzumi, J Inoguchi, Hiroya Ishikara, Mourad Ismail, Shin Isojima, Kenichi Ito, Yoshiaki Itoh, Masashi Iwasaki, Klara Janglajew, Michio Jimbo, Nalini Joshi, Kenji Kajiwara, Saburo Kakei, Masaru Kamata, Satoshi Kamei, Rinat Kashaev, Shingo Kawai, Taeko Kimijima, K Kimura, Anatol Kirillov, Koichi Kondo, Boris Konopelchenko, Martin Kruskal, Atsuo Kuniba, Wataru Kunishima, Franklin Lambert, Serguei Leble, Decio Levi, Shigeru Maeda, Manuel Manas, Ken-Ichi Maruno, Tetsu Masuda, J Matsukidaira, Atsushi Matsumiya, Shigeki Matsutani, Yukitaka Minesaki, Mikio Murata, Micheline Musette, Atsushi Nagai, Katsuya Nakagawa, Atsushi Nakamula, Akira Nakamura, Yoshimasa Nakamura, Frank Nijhoff, J J C Nimmo, Katsuhiro Nishinari, Michitomo Nishizawa, A Nobe, Masatoshi Noumi, Yaeko Ohsaki, Yasuhiro Ohta, Kazuo Okamoto, Alexandre Orlov, Naoki Osada, Flora Pempinelli, Spiro Pyrlis, Reinout Quispel, Orlando Ragnisco, Alfred Ramani, Jean-Pierre Ramis, Andreas Ruffing, Simon Ruijsenaars, Satoru Saito, Noriko Saitoh, Hidetaka Sakai, Paulo Santini, Narimasa Sasa, Ryu Sasaki, Yoshikatsu Sasaki, Junkichi Satsuma, Sergei Sergeev, Nobuhiko Shinzawa, Evgueni Sklyanin, Juris Suris, Norio Suzuki, Yukiko Tagami, Katsuaki Takahashi, Daisuke Takahashi, Tomoyuki Takenawa, Yoshiro Takeyama, K M Tamizhmani, T Tamizhmani, Kouichi Toda, Morikatsu Toda, Tetsuji Tokihiro, Takayuki Tsuchida, Yohei Tsuchiya, Teruhisa Tsuda, Satoru Tsujimoto, Walter Van Assche, Claude Viallet, Luc Vinet, Shinsuke Watanabe, Yoshihida Watanabe, Ralph Willox, Pavel Winternitz, Yasuhiko Yamada, Yuji Yamada, Jin Yoneda, Haruo Yoshida, Katsuhiko Yoshida, Daisuke Yoshihara, Fumitaka Yura, J

  11. Thermal and quantum fluctuations of confined Bose–Einstein condensate beyond the Bogoliubov approximation

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Y., E-mail: yusuke.n@asagi.waseda.jp [Department of Electronic and Physical Systems, Waseda University, Tokyo 169-8555 (Japan); Nagano Prefectural Kiso Seiho High School, Nagano 397-8571 (Japan); Kawaguchi, T., E-mail: pionelish30@toki.waseda.jp [Department of Electronic and Physical Systems, Waseda University, Tokyo 169-8555 (Japan); Torii, Y., E-mail: torii0139@asagi.waseda.jp [Department of Electronic and Physical Systems, Waseda University, Tokyo 169-8555 (Japan); Yamanaka, Y., E-mail: yamanaka@waseda.jp [Department of Electronic and Physical Systems, Waseda University, Tokyo 169-8555 (Japan)

    2017-01-15

    The formulation for zero mode of a Bose–Einstein condensate beyond the Bogoliubov approximation at zero temperature [Y. Nakamura et al., Phys. Rev. A 89 (2014) 013613] is extended to finite temperature. Both thermal and quantum fluctuations are considered in a manner consistent with a concept of spontaneous symmetry breakdown for a finite-size system. Therefore, we need a proper treatment of the zero mode operators, which invoke non-trivial enhancements in depletion condensate and thermodynamical quantities such as the specific heat. The enhancements are visible in the weak interaction case. Our approach reproduces the results of a homogeneous system in the Bogoliubov approximation in a large particle number limit.

  12. Method of cement-solidification of radioactive liquid wastes containing surfactant

    Energy Technology Data Exchange (ETDEWEB)

    Sugimoto, Y; Yusa, H

    1979-04-10

    Purpose: To provide the subject method comprising the steps of adjusting the concentration of the surfactant to a value less than the predetermined value even when the concentration of the surfactant is high, and rendering the uniaxial compression strength of the cement-solidification body into more than the defined fabrication reference value. Method: To radioactive liquid wastes there are applied means for boiling and heating liquid wastes by addition of sulfuric acid, means for cracking surfactants by the addition of oxidants and means for precipitating and arresting surfactants. After suppressing the hindrance of the cement hydration reaction by surfactants, the radioactive liquid wastes are cement-solidified. (Nakamura, S.).

  13. Treating agent for urea containing radioactive materials

    International Nuclear Information System (INIS)

    Ogawa, Hiroshi; Maki, Kentaro.

    1973-01-01

    Object: To add a coagulant into urea containing radioactive material to precipitate and remove the radioactive material in the urea. Structure: Iodosalt is added into urea and next, a mixed reagent in which silver ion or silver acetic ion and iron hydroxide precipitation or ferrite ion coexist is added therein. The urea is treated to have a sufficient alkaline, after which it is introduced into a basket type centrifuge formed with a filter layer in combination of an upper glass fiber layer and a lower active carbon layer. The treating agent can uniformly remove radioactive ion and radioactive chelate within urea containing inorganic salt and various metabolites. (Nakamura, S.)

  14. Treatment of nonalcoholic steatohepatitis with vitamins E and C: a pilot study

    Directory of Open Access Journals (Sweden)

    Kawanaka M

    2013-03-01

    Full Text Available Miwa Kawanaka,1 Ken Nishino,1 Jun Nakamura,1 Mitsuhiko Suehiro,1 Daisuke Goto,1 Noriyo Urata,1 Takahito Oka,1 Hirofumi Kawamoto,1 Hajime Nakamura,2 Junji Yodoi,3 Keisuke Hino,4 Gotaro Yamada11Department of Internal Medicine 2, Kawasaki Hospital, Kawasaki Medical School, Okayama, 2Department of Experimental Therapeutics, Translational Research Center, Kyoto University Hospital, Kyoto, 3Department of Biological Responses, Institute for Virus Research, Kyoto University, Kyoto, 4Department of Hepatology and Pancreatology, Kawasaki Medical School, Okayama, JapanBackground: Nonalcoholic steatohepatitis (NASH is a common liver disease that can progress to cirrhosis. Oxidative stress is one of the central mechanisms causing hepatocellular injury in the disease. In this study, antioxidant therapy using both vitamins C and E was conducted in patients with NASH.Methods: Vitamin E 300 mg/day and vitamin C 300 mg/day were administered orally to 23 patients with NASH for 12 months. Body mass index was measured during therapy. Serum levels of alanine aminotransferase, thioredoxin (an oxidative stress marker, and high-sensitivity C-reactive protein were measured before treatment and after 12 months in all patients. Ten of the 23 patients underwent liver biopsy before and after treatment.Results: Body mass index remained unchanged during treatment with vitamins C and E. Serum alanine aminotransferase, thioredoxin, and high-sensitivity C-reactive protein levels were decreased significantly at 12 months compared with pretreatment. Liver biopsies showed improved necroinflammatory activity in eight cases and improved fibrosis staging in 4.Conclusion: Serum alanine aminotransferase, thioredoxin, and high-sensitivity C-reactive protein levels, and liver histology were clearly improved with vitamin C and E therapy. These findings suggest that combination therapy using these vitamins may be useful in patients with NASH to minimize damage from oxidative stress and slow

  15. Efficacy and safety of combination therapy with latanoprost after a change in therapeutic regimen from timolol to brinzolamide in Japanese adult patients with primary open-angle glaucoma and ocular hypertension: open, non-randomized 12-week study

    Directory of Open Access Journals (Sweden)

    Shusaku Ishikawa

    2008-09-01

    Full Text Available Shusaku Ishikawa1, Yoshimi Nakamura1, Yuko Nakamura1, Hiroshi Sakai1, Shoichi Sawaguchi1, Kazuo Terashima2, Makoto Kanno2, Hidetoshi Yamashita21Department of Ophthalmology, University of the Ryukyus Faculty of Medicine, Okinawa, Japan; 2Department of Ophthalmology and Visual Science, Yamagata University Faculty of Medicine, Yamagata, JapanPurpose: To compare the efficacy of brinzolamide in Japanese patients with primary open-angle glaucoma (POAG or ocular hypertension (OH after a change from timolol in combination therapy with latanoprost.Methods: A 12-week, prospective, open-label, comparative study was performed in 20 patients [11 males and 9 females, mean age of 64.5 ± 11.0 (SDy] with POAG or OH treated with both latanoprost once daily and timolol 0.5% twice daily. During the study brinzolamide was substituted for timolol. Intraocular pressure (IOP was measured at baseline, 4, 8, and 12 weeks. Blood pressure (BP, pulse rate (PR, and adverse events were also recorded.Results: IOPs at baseline, 4, 8, and 12 weeks were 18.6 ± 2.1 mmHg, 17.8 ± 2.6 mmHg, 17.4 ± 2.5 mmHg, and 17.3 ± 3.5 mmHg, respectively. IOP reduction at 4 and 8 weeks was statistically significant (p < 0.05. The PR was significantly increased at 12 weeks (p < 0.01, but BP was not significantly affected. Four ocular adverse events were noted, but all were mild and transient.Conclusions: Substituting brinzolamide 1% for timolol 0.5% in combination therapy with latanoprost 0.005% demonstrated significant IOP reduction with improvement in PR with POAG or OH. Combination therapy using latanoprost and brinzolamide may be recommended for better IOP control with fewer systemic adverse events.Keywords: open-angle glaucoma, brinzolamide/latanprost combination therapy, timolol/latanoprost combination therapy, intraocular pressure

  16. Strongly correlated impurity band superconductivity in diamond: X-ray spectroscopic evidence

    Directory of Open Access Journals (Sweden)

    G. Baskaran

    2006-01-01

    Full Text Available In a recent X-ray absorption study in boron doped diamond, Nakamura et al. have seen a well isolated narrow boron impurity band in non-superconducting samples and an additional narrow band at the chemical potential in a superconducting sample. We interpret the beautiful spectra as evidence for upper Hubbard band of a Mott insulating impurity band and an additional metallic 'mid-gap band' of a conducting 'self-doped' Mott insulator. This supports the basic framework of a recent theory of the present author of strongly correlated impurity band superconductivity (impurity band resonating valence bond, IBRVB theory in a template of a wide-gap insulator, with no direct involvement of valence band states.

  17. Rotary plug

    International Nuclear Information System (INIS)

    Yamada, Keiji.

    1979-01-01

    Purpose: In a rotating plug of a reactor using a liquid metal as a coolant as in the case of a fbr type reactor, to prevent the ingress of Na vapor into the sliding surface of the rotating plug. Constitution: A rotating plug comprising a large disc covering the upper part of a reactor pressure vessel containing therein a liquid metal and forming surfaces for mounting a shielding device and various other devices, and at least one or more of small discs provided rotatably and eccentrically within said large disc, which is characterized in that an elastic member consisting of bellows and a sealing is interposed between said large disc and said small discs. (Nakamura, S.)

  18. Cleaning device for steam units in a nuclear power plant

    International Nuclear Information System (INIS)

    Sasamuro, Takemi.

    1978-01-01

    Purpose: To prevent radioactive contamination upon dismantling and inspection of steam units such as a turbine to a building containing such units and the peripheral area. Constitution: A steam generator indirectly heated by steam supplied from steam generating source in a separate system containing no radioactivity is provided to produce cleaning steam. A cleaning steam pipe is connected by way of a stop valve between separation valve of a nuclear power plant steam pipe and a high pressure turbine. Upon cleaning, the separation valve is closed, and steam supplied from the cleaning steam pipe is flown into a condenser. The water thus condensated is returned by way of a feed water heater and a condenser to a water storage tank. (Nakamura, S.)

  19. Device for preventing cooling water from flowing out of reactor

    International Nuclear Information System (INIS)

    Chinen, Masanori; Kotani, Koichi; Murase, Michio.

    1976-01-01

    Object: To provide emergency cooling system, which can prevent cooling water bearing radioactivity from flowing to the outside of the reactor at the time of breakage of feedwater pipe, thus eliminating the possibility of exposure of the fuel rod to provide high reliability and also reducing the possibility of causing radioactive pollution. Structure: The device for preventing cooling water from flowing out from the reactor features a jet nozzle inserted in a feedwater pipe adjacent to the inlet or outlet thereof immediately before the reactor container. The nozzle outlet is provided in the vicinity of the reactor wall and in a direction opposite to the direction of out-flow, and water supplied from a high pressure pump is jetted from it. (Nakamura, S.)

  20. The Linear Span of Projections in AH Algebras and for Inclusions of C*-Algebras

    Directory of Open Access Journals (Sweden)

    Dinh Trung Hoa

    2013-01-01

    Full Text Available In the first part of this paper, we show that an AH algebra A=lim→(Ai,ϕi has the LP property if and only if every element of the centre of Ai belongs to the closure of the linear span of projections in A. As a consequence, a diagonal AH-algebra has the LP property if it has small eigenvalue variation in the sense of Bratteli and Elliott. The second contribution of this paper is that for an inclusion of unital C*-algebras P⊂A with a finite Watatani index, if a faithful conditional expectation E:A→P has the Rokhlin property in the sense of Kodaka et al., then P has the LP property under the condition thatA has the LP property. As an application, let A be a simple unital C*-algebra with the LP property, α an action of a finite group G onto Aut(A. If α has the Rokhlin property in the sense of Izumi, then the fixed point algebra AG and the crossed product algebra A ⋊α G have the LP property. We also point out that there is a symmetry on the CAR algebra such that its fixed point algebra does not have the LP property.

  1. Effect of cultivation line and peeling on food composition, taste characteristic, aroma profile, and antioxidant activity of Shiikuwasha (Citrus depressa Hayata) juice.

    Science.gov (United States)

    Asikin, Yonathan; Fukunaga, Hibiki; Yamano, Yoshimasa; Hou, De-Xing; Maeda, Goki; Wada, Koji

    2014-09-01

    Shiikuwasha (Citrus depressa Hayata) juice from four main cultivation lines subjected to two peeling practices (with or without peeling) were discriminated in terms of quality attributes, represented by sugar and organic acid composition, taste characteristic, aroma profile, and antioxidant activity. Shiikuwasha juice from these lines had diverse food compositions; 'Izumi kugani' juice had lower acidity but contained more ascorbic acid than that of other cultivation lines. The composition of volatile aroma components was influenced by fruit cultivation line, whereas its content was affected by peeling process (20.26-53.73 mg L(-1) in whole juice versus 0.82-1.58 mg L(-1) in flesh juice). Peeling also caused Shiikuwasha juice to be less astringent and acidic bitter and to lose its antioxidant activity. Moreover, the total phenolic and ascorbic acid content of Shiikuwasha juice positively influenced its antioxidant activity. Each fruit cultivation line had a distinct food composition, taste characteristic, and aroma profile. Peeling in Shiikuwasha juice production might reduce aftertaste, and thus might improve its palatability. Comprehensive information on the effect of cultivation line and peeling on quality attributes will be useful for Shiikuwasha juice production, and can be applied to juice production of similar small citrus fruits. © 2014 Society of Chemical Industry.

  2. Managing refractory Crohn's disease: challenges and solutions

    Directory of Open Access Journals (Sweden)

    Tanida S

    2015-04-01

    Full Text Available Satoshi Tanida, Keiji Ozeki, Tsutomu Mizoshita, Hironobu Tsukamoto, Takahito Katano, Hiromi Kataoka, Takeshi Kamiya, Takashi Joh Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Aichi Prefecture, Japan Abstract: The goals of treatment for active Crohn's disease (CD are to achieve clinical remission and improve quality of life. Conventional therapeutics for moderate-to-severe CD include 5-aminosalicylic acid, corticosteroids, purine analogs, azathioprine, and 6-mercaptopurine. Patients who fail to respond to conventional therapy are treated with tumor necrosis factor (TNF-α inhibitors such as infliximab and adalimumab, but their efficacy is limited due to primary nonresponse or loss of response. It is suggested that this requires switch to another TNF-α inhibitor, a combination therapy with TNF-α blockade plus azathioprine, or granulocyte and monocyte adsorptive apheresis, and that other therapeutic options having different mechanisms of action, such as blockade of inflammatory cytokines or adhesion molecules, are needed. Natalizumab and vedolizumab are neutralizing antibodies directed against integrin a4 and a4ß7, respectively. Ustekinumab is a neutralizing antibody directed against the receptors for interleukin-12 and interleukin-23. Here, we provide an overview of therapeutic treatments that are effective and currently available for CD patients, as well as some that likely will be available in the near future. We also discuss the advantages of managing patients with refractory CD using a combination of TNF-α inhibitors plus azathioprine or intensive monocyte adsorptive apheresis. Keywords: adalimumab, granulocyte and monocyte adsorptive apheresis, combination therapy, complete remission

  3. SU-E-T-278: Dose Conformity Index for the Target in a Multitarget Environment

    Energy Technology Data Exchange (ETDEWEB)

    Harikrishnaperumal, Sudahar [Apollo Speciality Hospital, Chennai, Tamil Nadu (India)

    2015-06-15

    Purpose: The existing conformity index formulations are failing when multiple targets present outside the target of interest with same or different dose prescriptions. In the present study a novel methodology is introduced to solve this issue. Methods: The conformity index used by Nakamura et al (Int J Radiat Oncol Biol Phys 2001; 51(5):1313–1319) is taken as the base for this methodology. In this proposal, the prescription isodose volume (PIV) which normally includes the normal tissue and other target regions is restricted as PIV in annular regions of different thickness around the target of interest. The graphical line plotted between the thickness of annular region and the corresponding conformity index, will increase in the beginning and will reach a flat region, then it will increase again. The second increase in the conformity index depends basically on the distance between the targets, dose prescriptions, and size of the targets. The conformity index in the flat region should be the conformity index of the target of interest. This methodology was validated on dual target environment on a skull phantom in Multiplan planning system (Accuray Inc. Sunnyvale, USA) Results: When the surrounding target’s (sphere) size is changed from 1.5cm to 6cm diameter, the conformity index of the target of interest (3cm diameter) changed from 1.09 to 1.25. When the distance between the targets changed from 7.5cm to 2.5cm, the conformity index changed from 1.10 to 1.17. Similarly, when the prescribed dose changed from 25Gy to 50Gy the conformity index changed from 1.09 to 1.42. These values were above 2.0 when Nakamura et al formula was used. Conclusion: The proposed conformity index methodology eliminates the influence of surrounding targets to a greater extend. However, the limitations of this method should be studied further. Application of this method in clinical situations is the future scope.

  4. Nuclear reactor fuel replacement system

    International Nuclear Information System (INIS)

    Kayano, Hiroyuki; Joge, Toshio.

    1976-01-01

    Object: To permit the direction in which a fuel replacement unit is moving to be monitored by the operator. Structure: When a fuel replacement unit approaches an intermediate goal position preset in the path of movement, renewal of data display on a goal position indicator is made every time the goal position is changed. With this renewal, the prevailing direction of movement of the fuel replacement unit can be monitored by the operator. When the control of movement is initiated, the co-ordinates of the intermediate goal point A are displayed on a goal position indicator. When the replacement unit reaches point A, the co-ordinates of the next intermediate point B are displayed, and upon reaching point B the co-ordinates of the (last) goal point C are displayed. (Nakamura, S.)

  5. Three-body problem in quantum mechanics: Hyperspherical elliptic coordinates and harmonic basis sets

    International Nuclear Information System (INIS)

    Aquilanti, Vincenzo; Tonzani, Stefano

    2004-01-01

    Elliptic coordinates within the hyperspherical formalism for three-body problems were proposed some time ago [V. Aquilanti, S. Cavalli, and G. Grossi, J. Chem. Phys. 85, 1362 (1986)] and recently have also found application, for example, in chemical reaction theory [see O. I. Tolstikhin and H. Nakamura, J. Chem. Phys. 108, 8899 (1998)]. Here we consider their role in providing a smooth transition between the known 'symmetric' and 'asymmetric' parametrizations, and focus on the corresponding hyperspherical harmonics. These harmonics, which will be called hyperspherical elliptic, involve products of two associated Lame polynomials. We will provide an expansion of these new sets in a finite series of standard hyperspherical harmonics, producing a powerful tool for future applications in the field of scattering and bound-state quantum-mechanical three-body problems

  6. Method and device for marine disposal of radioactive wastes

    International Nuclear Information System (INIS)

    Tsuda, Shigeo.

    1978-01-01

    Purpose: To provide the subject method and device wherein a unit thrown away can body formed by firmly tying a several drum vessels is thrown away in seawater thereby carrying out a throw-away operation rapidly, safely and highly efficiently. Method: In the hatch is stacked in multistage a unit throw-away can body formed by firmly tying four drums. A self-travelling suspended bedplate with a thrown away rail device runs on rails, and is fixed to a necessary position. An accomodation and throwing away operation control chamber applied with radiation protection is attached to this self-travelling suspended bedplate to perform surveillance of the interior of the chamber, and accommodation and throwing away operation is carried out by a picture image sent from a television camera and safe and accurate operations. (Nakamura, S.)

  7. A case series of pregnancy- and lactation-associated osteoporosis and a review of the literature

    Directory of Open Access Journals (Sweden)

    Nakamura Y

    2015-09-01

    Full Text Available Yukio Nakamura,1,2 Mikio Kamimura,3 Shota Ikegami,1 Keijiro Mukaiyama,4 Masatoshi Komatsu,1 Shigeharu Uchiyama,1 Hiroyuki Kato11Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, 2Department of Orthopaedic Surgery, Showa Inan General Hospital, Komagane, 3Center of Osteoporosis and Spinal Disorders, Kamimura Clinic, Matsumoto, 4Department of Orthopaedic Surgery, Azumi General Hospital, Azumino, JapanAbstract: The syndrome of pregnancy- and lactation-associated osteoporosis is a rare disorder whose precise etiology and treatment are largely unknown. We herein report two such cases occurring in the early postpartum period that led to multiple fragility compression fractures. Combination therapy of vitamin D and vitamin K enabled a marked gradual increase in bone mineral density.Keywords: fracture, vitamin D, vitamin K, bone mineral density

  8. Reactor container

    International Nuclear Information System (INIS)

    Furukawa, Hideyasu; Oyamada, Osamu; Uozumi, Hiroto.

    1976-01-01

    Purpose: To provide a container for a reactor provided with a pressure suppressing chamber pool which can prevent bubble vibrating load, particularly negative pressure generated at the time of starting to release exhaust from a main steam escape-safety valve from being transmitted to a lower liner plate of the container. Constitution: This arrangement is characterized in that a safety valve exhaust pool for main steam escape, in which a pressure suppressing chamber pool is separated and intercepted from pool water in the pressure suppressing chamber pool, a safety valve exhaust pipe is open into said safety valve exhaust pool, and an isolator member, which isolates the bottom liner plate in the pressure suppressing chamber pool from the pool water, is disposed on the bottom of the safety valve exhaust pool. (Nakamura, S.)

  9. Distribution of K, Na, Th and U in sandstones and shales from western Shikoku, Japan

    International Nuclear Information System (INIS)

    Ishihara, Shunso; Sakamaki, Yukio; Mochizuki, Tsunekazu; Terashima, Shigeru; Endo, Yuji

    1981-01-01

    The regional variation of K, Na, Th and U distributions was studied on 58 sandstones, 81 shales and 3 green schists from the sedimentary terrains across western Shikoku. The geological structure of the studied district is explained. The regional characteristics of the sedimentary rocks are best demonstrated in the composition of the sandstones. The sandstones, in the source areas of which granitic and rhyolitic rocks exist and which have been deposited rapidly, were rich in K, whereas those derived mainly from mafic volcanic areas showed high Na content. The sandstones of the Shimanto Supergroup had the intermediate values, and K and K + Na contents became low in the south where the younger Upper Shimanto Group is exposed. Th and U in both sandstones and shales were highest in the Izumi Group, and generally low in the Shimanto Supergroup. The black shales of the Shimanto Supergroup did not show U-anomaly. In each group, highly matured rocks gave slightly higher Th/U ratio. Highly matured polycyclic sediments contained the least amount of radioactive elements. The radioactive anomaly due to the anomalous K contained in sericite, and that due to U in black shale were found in Chichibu and Sambosan belts. Similar anomaly was discovered in the foot wall of Mn deposits in the same zone. The possibility of anomalous U may be the least in the Shimanto Supergroup. (Kako, I.)

  10. Successful management of aortic thrombi resulting in spinal cord infarction in a patient with antiphospholipid antibody syndrome and acute cholecystitis

    Directory of Open Access Journals (Sweden)

    Izumi M

    2011-12-01

    Full Text Available Manabu Izumi, Shoko Teraoka, Keisuke Yamashita, Kenji Matsumoto, Tomohiro Muronoi, Yoshimitsu Izawa, Chikara Yonekawa, Masaki Ano, Masayuki SuzukawaDepartment of Emergency and Critical Care Medicine, Jichi Medical University, Tochigi, JapanAbstract: A 74-year-old man with coronary artery disease was suffering from acute nonobstructive cholecystitis and was admitted to a nearby hospital. Dual antiplatelet (aspirin and ticlopidine therapy was discontinued before preparation for surgical resection of the gall bladder. During his time in hospital he was aware of lumbar pain and weakness in both legs. He was transferred to our hospital for further evaluation and therapy. Diffuse intra-aortic thrombi were revealed by computed tomography with contrast media, and magnetic resonance imaging showed spinal cord infarction. However, computed tomography scans of the descending aorta obtained 4 months before admission exhibited no signs of atherosclerotic plaques or intra-aortic thrombi. Laboratory data suggest that antiphospholipid antibody syndrome might have caused these acute multiple intra-arterial thrombi. By restarting dual antiplatelet therapy and increasing the dose of heparin (from 10,000 IU/day to 15,000 IU/day we successfully managed the patient's clinical condition and symptoms. It is important to understand that stopping antiplatelet therapy may rapidly grow thrombi in patients with a hypercoagulative state.Keywords: intra-aortic thrombus, antiphospholipid antibody syndrome, spinal cord infarction

  11. Analysis of Foreign Exchange Interventions by Intervention Agent with an Artificial Market Approach

    Science.gov (United States)

    Matsui, Hiroki; Tojo, Satoshi

    We propose a multi-agent system which learns intervention policies and evaluates the effect of interventions in an artificial foreign exchange market. Izumi et al. had presented a system called AGEDASI TOF to simulate artificial market, together with a support system for the government to decide foreign exchange policies. However, the system needed to fix the amount of governmental intervention prior to the simulation, and was not realistic. In addition, the interventions in the system did not affect supply and demand of currencies; thus we could not discuss the effect of intervention correctly. First, we improve the system so as to make much of the weights of influential factors. Thereafter, we introduce an intervention agent that has the role of the central bank to stabilize the market. We could show that the agent learned the effective intervention policies through the reinforcement learning, and that the exchange rate converged to a certain extent in the expected range. We could also estimate the amount of intervention, showing the efficacy of signaling. In this model, in order to investigate the aliasing of the perception of the intervention agent, we introduced a pseudo-agent who was supposed to be able to observe all the behaviors of dealer agents; with this super-agent, we discussed the adequate granularity for a market state description.

  12. Tipepidine in adolescent patients with depression: a 4 week, open-label, preliminary study

    Directory of Open Access Journals (Sweden)

    Sasaki T

    2014-05-01

    Full Text Available Tsuyoshi Sasaki,1,2 Kenji Hashimoto,3 Masumi Tachibana,1 Tsutomu Kurata,1 Hiroshi Kimura,2 Hideki Komatsu,2 Masatomo Ishikawa,2 Tadashi Hasegawa,2 Akihiro Shiina,1 Tasuku Hashimoto,2 Nobuhisa Kanahara,4 Tetsuya Shiraishi,2 Masaomi Iyo1–41Department of Child Psychiatry, Chiba University Hospital, 2Department of Psychiatry, Chiba University Graduate School of Medicine, 3Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, 4Division of Medical Treatment and Rehabilitation, Chiba University Center for Forensic Mental Health, Inohana, Chiba, JapanDepression in children and adolescents is a common, recurrent, and debilitating condition associated with increased psychosocial, and medical morbidity and mortality.1The global prevalence of depression in children and adolescents is 1%–2% and 3%–8%, respectively.2 Depressive symptoms are also associated with significant functional impairment in school and the work place (often requiring legal interventions,1–5 and an increased risk for substance abuse and suicide.6–9 Clinical guidelines suggest the use of two selective serotonin reuptake inhibitors (SSRI, namely fluoxetine and escitalopram, both of which are effective with generally acceptable safety profiles in the treatment of adolescent depression.10 Additionally, combination treatment with an SSRI and psychotherapy, typically cognitive behavioral therapy (CBT, has shown benefit in this cohort.10 However, caution is warranted since antidepressants therapy in children and adolescents is associated with increased rates of suicidal ideation11–13 and adverse effects, characterized by excessive emotional arousal or behavioral activation.14 These results highlight the need for new therapies in adolescent patients with depression, particularly therapies with fewer side effects.View original paper by Brent and Maalouf.

  13. Successful treatment of two cases of urorectal septum malformation sequence with oligohydramnios and severe respiratory failure

    Directory of Open Access Journals (Sweden)

    Sekiguchi K

    2013-03-01

    Full Text Available Kazuhito Sekiguchi, Daijiro Takahashi, Takehiko Hiroma, Tomohiko Nakamura Division of Neonatology, Nagano Children's Hospital, Nagano, Japan Abstract: Urorectal septum malformation sequence can be diagnosed prenatally. We report herein the successful treatment of severe respiratory failure in two patients with urorectal septum malformation sequence and prenatally diagnosed oligohydramnios. The patients showed significant hypoxic deterioration and persistent pulmonary artery hypertension soon after birth. We used high-frequency ventilation (HFO, nitric oxide (NO, and extracorporeal membrane oxygenation (ECMO. The patients were successfully weaned from ECMO and artificial ventilation and discharged to home. Although termination of the pregnancy has often been selected for fetuses with oligohydramnios-related urorectal septum malformation sequence, our results suggest the opportunity for these fetuses to be treated using respiratory supports including HFO, NO, and ECMO after birth. Keywords: urorectal septum malformation sequence, oligohydramnios, pulmonary hypoplasia

  14. Creating understanding of reproductive health. Exchanges.

    Science.gov (United States)

    1997-02-01

    Yoko Komiyama, senior commentator of the Japan Broadcasting Corporation; Miyuki Nakamura, senior staff writer of Nihon Keizai Shimbun's Lifestyle News Department; and Miki Morimoto, staff writer for the Center for Research and Analysis on Global Issues Project 21, Asahi Shimbun, were introduced to population and reproductive health issues and the situation of women in Nepal during a December 8-16 interregional study tour. JOICFP selected the participants and organized an itinerary which provided insights into multilateral cooperation between UNFPA and the Ministry of Health (MOH) of Nepal, bilateral assistance between the Japan International Cooperation Agency and MOH, and nongovernmental organization collaboration between the Family Planning Association of Nepal and JOICFP. Upon returning to Japan, these representatives of three of Japan's major mass media groups shared their experiences with the general public through reports in newspapers, and on radio and television.

  15. Endoergic chemi-ionization in N-O collisions

    International Nuclear Information System (INIS)

    Nielsen, S.E.; Dahler, J.S.

    1979-01-01

    A semiclassical theory of endoergic chemi-ionization is developed and applied to the ionizing events that occur when ground state oxygen atoms collide with nitrogen atoms in the ground and first excited states. The approach used is an adaptation and extension of earlier theories due to Bardsley, Nakamura, and Miller. The theory relates the experimental associative (AI) and Penning ionization (PI) cross sections to the following events: formation of a stable diatomic ion (AI), neutral and ionized atomic fragments (PI), or of a metastable diatomic rotational resonance (DI, delayed ionization). The heavy particle motions are treated classically in terms of adiabatic potential energy functions, while localized nonadiabatic transitions also are taken into account by using the Landau-Zener approximation. Finally, the theoretical predictions compare well with the results of Ringer and Gentry's (1978) merged beam experiments

  16. Transformasi kebudayaan Islam di Kotagede

    Directory of Open Access Journals (Sweden)

    Nasiwan Nasiwan

    2015-10-01

    There are some main results of the research.l Prediction of Mitsuo Nakamura which stated that subculture of santri in Kotagede has capability to lead changes, is still releant and valid due to their nowadays practices of life. While some part ofhis thoughts is notmore valid because some politictd configuration at national level occurs. 2 Cultural traniformation occurs in Kotagede; which is especially inspired and generatedby subculture of Modernist Islam. There is a phenomenon that value standard which was decidedby Majelis Tatjih Muhammadiyah is partially ignored.Approach of dakwah (religious proselytizing got going to accommodate sym­bols and traditions ofsociety of Kotagede. "Undercover insubordination" against Tarjih Muhammadiyah has appeared as reflected in emergence of term "MUjA", abbreviated form Muhammadiyah jawa (Javanese Muhammadiyah,and of permissive culture.

  17. Extreme QCD 2012 (xQCD)

    Science.gov (United States)

    2013-04-01

    Acknowledgements This conference would not have been possible without the generous support from Brookhaven National Laboratory and the George Washington University INS and IMPACT institutes, Columbian College of Arts and Sciences, the Office of Vice-President for Research, and the Department of Physics. We thank them wholeheartedly. We are also very grateful for the support of our colleagues on the local organizing committee, Walter Freeman and Frank Lee, and on the International Advisory Committee: Simon Hands, Tetsuo Hatsuda, Frithjof Karsch, Maria Paola Lombardo, Tereza Mendes, Atsushi Nakamura, Owe Philipsen, Claudia Ratti, Paul Romatschke, Misha Stephanov, and Nu Xu. List of participants Alexandru, Andrei George Washington University Bazavov, Alexei Brookhaven National Laboratory Bloch, Jacques University of Regensburg Braun-Munzinger, Peter EMMI, GSI Breto Rangel, Guillermo CMS/UC Davis D'Elia, Massimo University of Pisa, INFN Dexheimer, Veronica UFSC - Federal University of Santa Catarina Ding, Heng-Tong Brookhaven National Laboratory Dion, Alan Stony Brook University Dumitru, Adrian RBRC and Baruch College, CUNY Freeman, Walter George Washington University Gavai, Rajiv Tata Institute (TIFR), Mumbai Hanada, Masanori KEK Theory Center Hands, Simon Swansea University Hegde, Prasad Brookhaven National Laboratory Heinke, Craig University of Alberta Horvath, Ivan University of Kentucky Karsch, Frithjof Brookhaven National Laboratory Krieg, Stefan Wuppertal University Lattimer, James Stony Brook University Lee, Frank George Washington University Li, Anyi Institute for Nuclear Theory Liu, Keh-Fei University of Kentucky Lombardo, Maria Paola INFN - LNF Lottini, Stefano Goethe University, Frankfurt am Main Maezawa, Yu Brookhaven National Laboratory Miura, Kohtaroh Laboratori Nazionali di Frascati - INFN Monnai, Akihiko The University of Tokyo Mukherjee, Swagato Brookhaven National Laboratory Myers, Joyce University of Groningen Nakamura, Atsushi RIISE, Hiroshima

  18. Pitch Angle Scattering of Energetic Electrons by Plasmaspheric Hiss Emissions

    Science.gov (United States)

    Tobita, M.; Omura, Y.; Summers, D.

    2017-12-01

    We study scattering of energetic electrons in pitch angles and kinetic energies through their resonance with plasmaspheric hiss emissions consisting of many coherent discrete whistler-mode wave packets with rising and falling frequencies [1,2,3]. Using test particle simulations, we evaluate the efficiency of scattering, which depends on the inhomogeneity ratio S of whistler mode wave-particle interaction [4]. The value of S is determined by the wave amplitude, frequency sweep rate, and the gradient of the background magnetic field. We first modulate those parameters and observe variations of pitch angles and kinetic energies of electrons with a single wave under various S values so as to obtain basic understanding. We then include many waves into the system to simulate plasmaspheric hiss emissions. As the wave packets propagate away from the magnetic equator, the nonlinear trapping potential at the resonance velocity is deformed, making a channel of gyrophase for untrapped electrons to cross the resonance velocity, and causing modulations in their pitch angles and kinetic energies. We find efficient scattering of pitch angles and kinetic energies because of coherent nonlinear wave-particle interaction, resulting in electron precipitations into the polar atmosphere. We compare the results with the bounce averaged pitch angle diffusion coefficient based on quasi-linear theory, and show that the nonlinear wave model with many coherent packets can cause scattering of resonant electrons much faster than the quasi-linear diffusion process. [1] Summers, D., Omura, Y., Nakamura, S., and C. A. Kletzing (2014), Fine structure of plasmaspheric hiss, J. Geophys. Res., 119, 9134-9149. [2] Omura, Y., Y. Miyashita, M. Yoshikawa, D. Summers, M. Hikishima, Y. Ebihara, and Y. Kubota (2015), Formation process of relativistic electron flux through interaction with chorus emissions in the Earth's inner magnetosphere, J. Geophys. Res. Space Physics, 120, 9545-9562. [3] Nakamura, S., Y

  19. Stemcell Information: SKIP000222 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available EN-12A HPS0029 HPS0029 ... -- Male ... -- No Human iPS cell line. ヒトiPS細胞株。臍帯由来線維芽細胞由来。 human ES-like... SKIP000222 ... Umbilical cord(Fibroblast) 臍帯（線維芽細胞） Normal HiPS-RIKEN-12A HiPS-RIK... -- Retrovirus Retroviral vector pMXs, Oct3/4, Sox2, Klf4 ... Yes MEF (X-rays:5000R or MMC) 1-1.5x10^(6) cells/...N BRC 理化学研究所バイオリソースセンター Yukio Nakamura 中村幸夫 Available RIKEN BRC 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0029&type=1 ...

  20. The radiation protection design of CSR

    Energy Technology Data Exchange (ETDEWEB)

    Su Youwu; Zheng Huazhi; Zhu Xiaolong; Li Shuwei [Institute of modern physics, the Chinese academy of Sciences, Lanzhou (China)

    2000-05-01

    The construction of CSR (Cooling Storage Ring) which include a main ring (CSRm) and an experimental ring (CSRe) will be started in this year. Heavy ions of carbon to uranium will be accelerated up to 900MeV/u and 400MeV/u at intensity of 10{sup 8} pps. For the shielding design of CSR, the secondary neutron yields due to ion beam loss and their spectra, angular distributions were estimated based on the experimental results for 400 MeV/u {sup 12}C+Cu reaction by K. Nakamura et.al.. The equivalent dose at the shield surface and in the surrounding environment, skyshine neutron dose equivalent and air-induced radioactivity were also estimated in this study. It is found that the most important environmental radiation impact component of CSR is the skyshine neutrons, and the environmental impact due to air and cooling water induced radioactivity were lesser. (author)

  1. A Dancing Black Hole

    Science.gov (United States)

    Shoemaker, Deirdre; Smith, Kenneth; Schnetter, Erik; Fiske, David; Laguna, Pablo; Pullin, Jorge

    2002-04-01

    Recently, stationary black holes have been successfully simulated for up to times of approximately 600-1000M, where M is the mass of the black hole. Considering that the expected burst of gravitational radiation from a binary black hole merger would last approximately 200-500M, black hole codes are approaching the point where simulations of mergers may be feasible. We will present two types of simulations of single black holes obtained with a code based on the Baumgarte-Shapiro-Shibata-Nakamura formulation of the Einstein evolution equations. One type of simulations addresses the stability properties of stationary black hole evolutions. The second type of simulations demonstrates the ability of our code to move a black hole through the computational domain. This is accomplished by shifting the stationary black hole solution to a coordinate system in which the location of the black hole is time dependent.

  2. The radiation protection design of CSR

    International Nuclear Information System (INIS)

    Su Youwu; Zheng Huazhi; Zhu Xiaolong; Li Shuwei

    2000-01-01

    The construction of CSR (Cooling Storage Ring) which include a main ring (CSRm) and an experimental ring (CSRe) will be started in this year. Heavy ions of carbon to uranium will be accelerated up to 900MeV/u and 400MeV/u at intensity of 10 8 pps. For the shielding design of CSR, the secondary neutron yields due to ion beam loss and their spectra, angular distributions were estimated based on the experimental results for 400 MeV/u 12 C+Cu reaction by K. Nakamura et.al.. The equivalent dose at the shield surface and in the surrounding environment, skyshine neutron dose equivalent and air-induced radioactivity were also estimated in this study. It is found that the most important environmental radiation impact component of CSR is the skyshine neutrons, and the environmental impact due to air and cooling water induced radioactivity were lesser. (author)

  3. The characteristics of keratomycosis by Beauveria bassiana and its successful treatment with antimycotic agents

    Directory of Open Access Journals (Sweden)

    Hiroko Sonoyama

    2008-10-01

    Full Text Available Hiroko Sonoyama1, Kaoru Araki-Sasaki1, Shigeyasu Kazama1, Tsutomu Kawasaki1, Hidenao Ideta1, Atsuko Sunada2, Seishi Asari2, Yoshitsugu Inoue3, Kozaburo Hayashi41Ideta Eye Hospital, Kumamoto, Kumamoto, Japan; 2Department of Laboratory for Clinical Investigation, Osaka University Hospital, Suita, Osaka, Japan; 3Division of Ophthalmology and Visual Science, Department of Medicine of Sensory and Motor Organ, Tottori University, Yonago, Tottori, Japan; 4Immunology and Virology Section Lab, Immunology, NEI, NIH, Bethesda, MD, USAAbstract: Clinical findings and treatment of keratomycosis caused by Beauveria bassiana, an entomopathogenic filamentous fungus, are described for an 80-year-old woman, who was referred to the hospital for ocular pain and redness on the 9th day after an ocular injury caused by the frame of her glasses. She had a long history of recurrent diabetic iritis and continuously used topical antibiotics and corticosteroids. At her first visit, a slit-lamp examination indicated a corneal ulcer confined within the superficial stromal layer, along with a slight infiltration and edema. Only a very few inflammatory cells were seen in the anterior chamber. Direct microscopic examination of corneal scrapings revealed septate fungal hyphae with zig-zag rachis and budding that was subsequently identified as B. bassiana by slide culture. Topical voriconazole with miconazole, pimaricin and oral itraconazole were effective and the lesion disappeared leaving only a mild scar at 2 months. The sensitivity of B. bassiana to various antimycotic agents was confirmed by broth microdilution, agar dilution with the Clinical Laboratory Standard Institute standard, and a disk method using topically applied concentrations. B. bassiana, which exhibits a characteristic appearance in smears and causes superficial keratomycosis, is sensitive to voriconazole with miconazole, pimaricin, and itraconazole.Keywords: Beauveria bassiana, keratomycosis, filamentous

  4. Report on field test project for wind power development at Nagashima-cho. Detailed wind characteristics survey; Nagashimacho ni okeru furyoku field test jigyo (fukyo seisa) hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    A detailed wind characteristics survey was conducted to study the feasibility of a wind power generation system for Nagashima-cho, Izumi-gun, Kagoshima Prefecture. Observation instruments were installed at the top of a hill approximately 80m above the sea level situated to the northwest of the Nagashima-cho town hall and, in the period October 1998 through September 1999, data were collected at a point 20m above ground, such as the average wind speed and direction, wind velocity standard deviation, and the maximum instantaneous wind velocity. The data were analyzed, and findings were obtained, as mentioned below. The annual average wind speed was 5.0m, strong in winter and weak in summer. The annual wind direction occurrence rate was 61.8%, turbulence intensity was 0.17 at wind speeds of 4m/s and more, these not presenting any particular problem. Wind energy density was 148W/m{sup 2}. Both wind speed conditions and energy density were slightly lower than the reference levels indicated for evaluation. Studies were made on the assumption that three classes of wind turbines (150, 300, and 750kW) would be introduced, and then it was found that both operating factors and facility availability rates exceeded the required levels. Since there were no detrimental factors in the surrounding conditions, it was concluded that possibilities were high that wind power generation at the site would be practical. (NEDO)

  5. Seismic reflection survey of the Uemachi fault in Osaka Prefecture; Osaka Uemachi danso no hanshaho danseiha tansa

    Energy Technology Data Exchange (ETDEWEB)

    Sugiyama, Y [Geological Survey of Japan, Tsukuba (Japan); Yoshizawa, M; Hirooka, S [Nikko Exploration and Development Co. Ltd., Tokyo (Japan); Yokota, H; Ito, S [Hanshin Consultant Co., Osaka (Japan); Hayashi, K; Aizawa, H

    1997-05-27

    Reflection survey is conducted using three traverse lines in Sakai City for confirming the presence of a southward stretch of the Uemachi fault underground along the western periphery of the Uemachi terrace, Osaka, and for elucidating its connection to the Sakamoto fault distributed near Izumi. Another reflection survey is conducted in the bed of Kanzaki river, Osaka, for the confirmation of its connection to the Nembutsuji-zan fault in Senri hillock. It is estimated on the basis of boring data that there exists another flexural structure approximately 3km south of the flexural structure whose presence is confirmed by the Sakai second traverse line. Accordingly, possibilities are high that the southward stretch of the Uemachi fault connects to the Sakamoto fault. The confirmation by the Kanzaki river traverse line of the flexural structure again confirms the continuity between the Uemachi fault and Nembutsuji-zan fault. The above-said findings enable an inference that the three faults of Nembutsuji-zan, Uemachi, and Sakamoto constitute a chain of active faults. Furthermore, there exists an active fault to the south of the Sakamoto fault, which zigzags to the south on the right-hand side as far as the south of the Kumeda pond. Accordingly, the Uemachi fault system as a whole spans approximately 43km from the northern end of the Nembutsuji-zan fault as far as the south of the Kumeda pond. 5 refs., 6 figs.

  6. Quantum Cryptography Based on the Deutsch-Jozsa Algorithm

    Science.gov (United States)

    Nagata, Koji; Nakamura, Tadao; Farouk, Ahmed

    2017-09-01

    Recently, secure quantum key distribution based on Deutsch's algorithm using the Bell state is reported (Nagata and Nakamura, Int. J. Theor. Phys. doi: 10.1007/s10773-017-3352-4, 2017). Our aim is of extending the result to a multipartite system. In this paper, we propose a highly speedy key distribution protocol. We present sequre quantum key distribution based on a special Deutsch-Jozsa algorithm using Greenberger-Horne-Zeilinger states. Bob has promised to use a function f which is of one of two kinds; either the value of f( x) is constant for all values of x, or else the value of f( x) is balanced, that is, equal to 1 for exactly half of the possible x, and 0 for the other half. Here, we introduce an additional condition to the function when it is balanced. Our quantum key distribution overcomes a classical counterpart by a factor O(2 N ).

  7. Microstructure of III-N semiconductors related to their applications in optoelectronics

    Science.gov (United States)

    Leszczynski, M.; Czernetzki, R.; Sarzynski, M.; Krysko, M.; Targowski, G.; Prystawko, P.; Bockowski, M.; Grzegory, I.; Suski, T.; Domagala, J.; Porowski, S.

    2005-03-01

    There has been more than a decade since Shuji Nakamura from Japanese company Nichia constructed the first blue LED based on structure of (AlGaIn)N semiconductor and eight years since he made the first blue laser diode (LD). This work gives a survey on the current technological status with green/blue/violet/UV optoelectronics based on III-N semiconductors in relation with their microstructure. The following devices are presented: i) Low-power green and blue LEDs, ii) High-power LEDs targeting solid-state white lighting, iii) Low-power violet LDs for high definition DVD market, iv) High-power violet LDs, v) UV LEDs. The discussion will be focused on three main technological problems related to the microstructure of (AlGaIn)N layers in emitters based on III-N semiconductors: i) high density of dislocations in epitaxial layers of GaN on foreign substrates (sapphire, SiC, GaAs), ii), presence of strains, iii) atom segregation in ternary and quaternary compounds.

  8. Nivolumab in the treatment of malignant melanoma: review of the literature

    Directory of Open Access Journals (Sweden)

    Mashima E

    2015-08-01

    Full Text Available Emi Mashima, Akiha Inoue, Yumiko Sakuragi, Takashi Yamaguchi, Natsuko Sasaki, Yoko Hara, Daisuke Omoto, Shun Ohmori, Sanehito Haruyama, Yu Sawada, Manabu Yoshioka, Daisuke Nishio, Motonobu Nakamura Department of Dermatology, University of Occupational and Environmental Health, Kitakyushu, Japan Abstract: Nivolumab was developed as a monoclonal antibody against programmed death receptor-1, an immune checkpoint inhibitor which negatively regulates T-cell proliferation and activation. Intravenous administration of nivolumab was approved for the treatment of unresectable malignant melanoma in 2014 in Japan. When advanced melanoma patients were treated with nivolumab, median overall survival became longer. Overall survival rate was significantly better in nivolumab-treated melanoma patients than dacarbazine-treated melanoma patients. Nivolumab had an acceptable long-term tolerability profile, with 22% of patients experiencing grade 3 or 4 adverse events related to the drug. Therefore, nivolumab can become an alternative therapy for advanced malignant melanoma. Keywords: monoclonal antibody, PD-1, PD-L1

  9. Lead-free piezoelectrics based on potassium-sodium niobate with giant d(33).

    Science.gov (United States)

    Zhang, Binyu; Wu, Jiagang; Cheng, Xiaojing; Wang, Xiaopeng; Xiao, Dingquan; Zhu, Jianguo; Wang, Xiangjian; Lou, Xiaojie

    2013-08-28

    High-performance lead-free piezoelectrics (d33 > 400 pC/N) based on 0.96(K0.5Na0.5)0.95Li0.05Nb1-xSbxO3-0.04BaZrO3 with the rhombohedral-tetragonal (R-T) phase boundary have been designed and prepared. The R-T phase boundary lies the composition range of 0.04 ≤ x ≤ 0.07, and the dielectric and piezoelectric properties of the ceramics with the compositions near the phase boundary are significantly enhanced. In addition, the ceramic with x = 0.07 has a giant d33 of ~425 pC/N, which is comparable to that (~416 pC/N) of textured KNN-based ceramics (Saito, Y.; Takao, H.; Tani, T.; Nonoyama, T.; Takatori, K.; Homma, T.; Nagaya, T.; Nakamura, M. Nature 2004, 432, 84). The underlying physical mechanisms for enhanced piezoelectric properties are addressed. We believe that the material system is the most promising lead-free piezoelectric candidates for the practical applications.

  10. Boolean Approach to Dichotomic Quantum Measurement Theories

    Energy Technology Data Exchange (ETDEWEB)

    Nagata, K. [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of); Nakamura, T. [Keio University, Yokohama (Japan); Batle, J. [Universitat de les Illes Balears, Balearic Islands (Spain); Abdalla, S. [King Abdulaziz University Jeddah, Jeddah (Saudi Arabia); Farouk, A. [Al-Zahra College for Women, Muscat (Egypt)

    2017-02-15

    Recently, a new measurement theory based on truth values was proposed by Nagata and Nakamura [Int. J. Theor. Phys. 55, 3616 (2016)], that is, a theory where the results of measurements are either 0 or 1. The standard measurement theory accepts a hidden variable model for a single Pauli observable. Hence, we can introduce a classical probability space for the measurement theory in this particular case. Additionally, we discuss in the present contribution the fact that projective measurement theories (the results of which are either +1 or −1) imply the Bell, Kochen, and Specker (BKS) paradox for a single Pauli observable. To justify our assertion, we present the BKS theorem in almost all the two-dimensional states by using a projective measurement theory. As an example, we present the BKS theorem in two-dimensions with white noise. Our discussion provides new insight into the quantum measurement problem by using this measurement theory based on the truth values.

  11. Stemcell Information: SKIP000221 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available N-2A HPS0009 HPS0009 ... -- Male ... -- No Human iPS cell line. ヒトiPS細胞。臍帯由来線維芽細胞（RCB0197 HUC-Fm）由来。 ... SKIP000221 ... Umbilical cord(Fibroblast) 臍帯（線維芽細胞） Normal HiPS-RIKEN-2A HiPS-RIKE...human ES-like -- Retrovirus Retroviral vector pMXs, Oct3/4, Sox2, Klf4, c-Myc ... Yes MEF (X-rays:5000R or MMC) 1-1.5x10^(6) cell.../www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0009&type=1 ... ...学研究所バイオリソースセンター RIKEN BRC 理化学研究所バイオリソースセンター Yukio Nakamura 中村幸夫 Available RIKEN BRC 理化学研究所バイオリソースセンター http:/

  12. Electrocoagulation of the Locus coeruleus and the plasma catecholamine responses to immobilization stress in normotensive and hypertensive rats

    International Nuclear Information System (INIS)

    Dronjak, S.; Nikolic, J.; Varagic, V.M.

    1998-01-01

    The Locus coeruleus (LC), the largest noradrenergic nucleus in the brain, plays a major role in behavioral arousal in response to novel or stressful stimuli (Foote et al, 1983). An interesting feature of the LC is the degree of plasticity it displays in response to stress or drug treatment. For example, electrophysiological evidence suggests that sprouting of LC axons may occur following repeated stress (Sakaguchi and Nakamura, 1990). Stress increases LC firing rate and results in increased levels of noradrenaline (Glavin et al, 1983). High concentrations of noradrenergic neurons in LC indicated that this structure might have an integrative role in the blood pressure regulation. Spontaneously hypertensive rats (SHP) are widely used as a model of human essential hypertension. These animals exhibit enhanced sympathetic activity (Brody et al, 1980). It was therefore of interest to study the role of LC in normotensive and spontaneously hypertensive rats, and the effect of unilateral and bilateral electrocoagulation of the LC on the plasma concentration of noradrenaline and adrenaline during immobilization stress. (author)

  13. Adequate nutrition status important for bone mineral density improvement in a patient with anorexia nervosa

    Directory of Open Access Journals (Sweden)

    Nakamura Y

    2018-05-01

    Full Text Available Yukio Nakamura,1,2 Mikio Kamimura,3 Hidefumi Koiwai,4 Hiroyuki Kato1 1Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan; 2Department of Orthopedic Surgery, Showa-Inan General Hospital, Komagane, Japan; 3Center of Osteoporosis and Spinal Disorders, Kamimura Orthopedic Clinic, Matsumoto, Japan; 4Koiwai Orthopedic Clinic, Komoro, Japan Abstract: Low bone mineral density (BMD is one of the most frequent complications of anorexia nervosa (AN. We report the clinical outcomes of a female patient with severe AN, whose chest had become deformed due to thoracic fracture. Lumbar BMD was 0.358 g/cm2 (T-score = −6.3, and total hip BMD was 0.411 g/cm2 (T-score = −4.4. Active vitamin D increased these parameters by 81.0% and 57.4%, respectively, but a drop in her nutrition status afterward resulted in a sharp decrease in BMD values. These findings suggest that adequate nutrient intake is essential for effective osteoporosis treatment in patients with AN. Keywords: anorexia nervosa, bone mineral density, daily teriparatide, osteoporosis

  14. Proceedings of the first symposium on utilization of research reactors and JMTR

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The first symposium on utilization of research reactors (JRR-2, JRR-3M, JRR-4) and Japan Materials Testing Reactor (JMTR) in JAERI was held from September 29th to 30th, 1997 at Sannomaru Hotel, Mito. The purpose of this symposium is to announce contribution to progress of scientific technology as well as to promote future utilization of the research reactors and JMTR. During the symposium, 16 reports were presented on nuclear fuel and material, neutron beam experiment, medical irradiation, radioisotope production and neutron activation analysis. The present status of the research reactors and JMTR were also reported. The special lecture titled `JRR-2 and Medical Irradiation` was given by Mr. Nakamura, former editorial writer of Yomiuri. Finally, panel discussion was carried on `The Role of Research Reactors and JMTR in Scientific Technology for the future` actively by the participants and experts in every field of research reactor utilization. 250 people participated in this symposium from universities, national research institutes, private corporations and JAERI. This proceedings briefly summarizes 16 reports, the content of panel discussion and so forth. (J.P.N.)

  15. Application of microtremor horizontal-to-vertical spectral ratio (MHVSR) analysis for site characterization: State of the art

    Science.gov (United States)

    Molnar, S.; Cassidy, J. F.; Castellaro, S.; Cornou, C.; Crow, H.; Hunter, J. A.; Matsushima, S.; Sanchez-Sesma, F. J.; Yong, Alan

    2018-01-01

    Nakamura (Q Rep Railway Tech Res Inst 30:25–33, 1989) popularized the application of the horizontal-to-vertical spectral ratio (HVSR) analysis of microtremor (seismic noise or ambient vibration) recordings to estimate the predominant frequency and amplification factor of earthquake shaking. During the following quarter century, popularity in the microtremor HVSR (MHVSR) method grew; studies have verified the stability of a site’s MHVSR response over time and validated the MHVSR response with that of earthquake HVSR response. Today, MHVSR analysis is a popular reconnaissance tool used worldwide for seismic microzonation and earthquake site characterization in numerous regions, specifically, in the mapping of site period or fundamental frequency and inverted for shear-wave velocity depth profiles, respectively. However, the ubiquity of MHVSR analysis is predominantly a consequence of its ease in application rather than our full understanding of its theory. We present the state of the art in MHVSR analyses in terms of the development of its theoretical basis, current state of practice, and we comment on its future for applications in earthquake site characterization.

  16. Siegert pseudostate formulation of scattering theory: two-channel case

    CERN Document Server

    Sitnikov, G V

    2003-01-01

    Siegert pseudostates (SPS) are a finite basis representation of Siegert states (SS) for finite-range potentials. This paper presents a generalization of the SPS formulation of scattering theory, originally developed by Tolstikhin, Ostrovsky, and Nakamura ÝPhys. Rev. A 58, 2077 (1998)¿ for s-wave scattering in the one-channel case, to s-wave scattering in the two-channel case. This includes the investigation of the properties of orthogonality and completeness of two-channel SPS and the derivation of the SPS expansions for the two- channel Green function, wave function, and scattering matrix. Similar to the one-channel case, two types of expansions for the scattering matrix are obtained: one has a form of a sum and requires the knowledge of both the SPS eigenvalues and eigenfunctions, while the other has a form of a product and involves the eigenvalues only. As the size of the basis tends to infinity, the product formulas obtained here in terms of SPS coincide with those given by Le Couteur ÝProc. R. Soc. Lo...

  17. Device for detecting failure of reactor system

    International Nuclear Information System (INIS)

    Miyazawa, Tatsuo.

    1979-01-01

    Purpose: To make it possible to rapidly detect any failure in a reactor system prior to the leakage of coolants. Constitution: The dose of beta line is computed from the difference between the power of a detector for reacting with both beta and gamma lines and a detector for reacting only with gamma line to detect the failure of a reactor system, thereby to raise the detection speed and improve the detection accuracy. More specifically, a radiation detector A detects gamma and beta lines by means of piezoelectric elements. A radiation detector B caused the opening of the detector A to be covered with a metal, and detects only gamma line. The detected values of detectors A and B are amplified by an amplifier and applied to a rate meter and a counter, the values being converted into DC and introduced into a comparison circuit, where the outputs of the rate meter are compared with each other. When the difference is more than the predetermined range, it is supplied as output to an alarm circuit where an alarm signal is produced. (Nakamura, S.)

  18. Laser mass spectrometry for DNA fingerprinting for forensic applications

    Energy Technology Data Exchange (ETDEWEB)

    Chen, C.H.; Tang, K.; Taranenko, N.I.; Allman, S.L.; Chang, L.Y.

    1994-12-31

    The application of DNA fingerprinting has become very broad in forensic analysis, patient identification, diagnostic medicine, and wildlife poaching, since every individual`s DNA structure is identical within all tissues of their body. DNA fingerprinting was initiated by the use of restriction fragment length polymorphisms (RFLP). In 1987, Nakamura et al. found that a variable number of tandem repeats (VNTR) often occurred in the alleles. The probability of different individuals having the same number of tandem repeats in several different alleles is very low. Thus, the identification of VNTR from genomic DNA became a very reliable method for identification of individuals. DNA fingerprinting is a reliable tool for forensic analysis. In DNA fingerprinting, knowledge of the sequence of tandem repeats and restriction endonuclease sites can provide the basis for identification. The major steps for conventional DNA fingerprinting include (1) specimen processing (2) amplification of selected DNA segments by PCR, and (3) gel electrophoresis to do the final DNA analysis. In this work we propose to use laser desorption mass spectrometry for fast DNA fingerprinting. The process and advantages are discussed.

  19. Moved range monitor of a refueling machine

    International Nuclear Information System (INIS)

    Nakajima, Masaaki; Sakanaka, Tadao; Kayano, Hiroyuki.

    1976-01-01

    Purpose: To incorporate light receiving and emitting elements in a face monitor to thereby increase accuracy and reliability to facilitate handling in the refueling of a BWR power plant. Constitution: In the present invention, a refueling machine and a face monitoring light receiving and emitting elements are analogously coupled whereby the face monitoring light receiving and emitting elements may be moved so as to be analogous to a route along which the refueling machine has moved. A shielding plate is positioned in the middle of the light receiving and emitting elements, and the shielding plate is machined so as to be outside of action. The range of action of the refueling machine may be monitored depending on the light receiving state of the light receiving element. Since the present invention utilizes the permeating light as described above, it is possible to detect positions more accurately than the mechanical switch. In addition, the detection section is of the non-contact system and the light receiving element comprises a hot cell, and therefore the service life is extended and the reliability is high. (Nakamura, S.)

  20. Relativistic hydrodynamics in the presence of puncture black holes

    International Nuclear Information System (INIS)

    Faber, Joshua A.; Etienne, Zachariah B.; Shapiro, Stuart L.; Taniguchi, Keisuke; Baumgarte, Thomas W.

    2007-01-01

    Many of the recent numerical simulations of binary black holes in vacuum adopt the moving puncture approach. This successful approach avoids the need to impose numerical excision of the black hole interior and is easy to implement. Here we wish to explore how well the same approach can be applied to moving black hole punctures in the presence of relativistic hydrodynamic matter. First, we evolve single black hole punctures in vacuum to calibrate our Baumgarte-Shapiro-Shibata-Nakamura implementation and to confirm that the numerical solution for the exterior spacetime is invariant to any junk (i.e., constraint-violating) initial data employed in the black hole interior. Then we focus on relativistic Bondi accretion onto a moving puncture Schwarzschild black hole as a numerical test bed for our high-resolution shock-capturing relativistic hydrodynamics scheme. We find that the hydrodynamical equations can be evolved successfully in the interior without imposing numerical excision. These results help motivate the adoption of the moving puncture approach to treat the binary black hole-neutron star problem using conformal thin-sandwich initial data

  1. Application of Microtremor Horizontal-to-Vertical Spectral Ratio (MHVSR) Analysis for Site Characterization: State of the Art

    Science.gov (United States)

    Molnar, S.; Cassidy, J. F.; Castellaro, S.; Cornou, C.; Crow, H.; Hunter, J. A.; Matsushima, S.; Sánchez-Sesma, F. J.; Yong, A.

    2018-03-01

    Nakamura (Q Rep Railway Tech Res Inst 30:25-33, 1989) popularized the application of the horizontal-to-vertical spectral ratio (HVSR) analysis of microtremor (seismic noise or ambient vibration) recordings to estimate the predominant frequency and amplification factor of earthquake shaking. During the following quarter century, popularity in the microtremor HVSR (MHVSR) method grew; studies have verified the stability of a site's MHVSR response over time and validated the MHVSR response with that of earthquake HVSR response. Today, MHVSR analysis is a popular reconnaissance tool used worldwide for seismic microzonation and earthquake site characterization in numerous regions, specifically, in the mapping of site period or fundamental frequency and inverted for shear-wave velocity depth profiles, respectively. However, the ubiquity of MHVSR analysis is predominantly a consequence of its ease in application rather than our full understanding of its theory. We present the state of the art in MHVSR analyses in terms of the development of its theoretical basis, current state of practice, and we comment on its future for applications in earthquake site characterization.

  2. Development of reactor design aid tool using virtual reality technology

    International Nuclear Information System (INIS)

    Mizuguchi, N.; Tamura, Y.; Imagawa, S.; Sagara, A.; Hayashi, T.

    2006-01-01

    A new type of aid system for fusion reactor design, to which the virtual reality (VR) visualization and sonification techniques are applied, is developed. This system provides us with an intuitive interaction environment in the VR space between the observer and the designed objects constructed by the conventional 3D computer-aided design (CAD) system. We have applied the design aid tool to the heliotron-type fusion reactor design activity FFHR2m [A. Sagara, S. Imagawa, O. Mitarai, T. Dolan, T. Tanaka, Y. Kubota, et al., Improved structure and long -life blanket concepts for heliotron reactors, Nucl. Fusion 45 (2005) 258-263] on the virtual reality system CompleXcope [Y. Tamura, A. Kageyama, T. Sato, S. Fujiwara, H. Nakamura, Virtual reality system to visualize and auralize numerical imulation data, Comp. Phys. Comm. 142 (2001) 227-230] of the National Institute for Fusion Science, Japan, and have evaluated its performance. The tool includes the functions of transfer of the observer, translation and scaling of the objects, recording of the operations and the check of interference

  3. Determinación de los periodos predominantes de los depósitos de suelo de Tunja y Sogamoso usando microtemblores

    Directory of Open Access Journals (Sweden)

    Orlando Rincón Arango

    2010-11-01

    Full Text Available En el estudio fueron evaluados los periodos de losdepósitos de suelo mediante la relación H/V, técnicade Nakamura aplicada a registros de microtemblores;los registros fueron realizados en puntos del área urbanapara las ciudades de Tunja y Sogamoso (Boyacá,Colombia; se incluyó el análisis de estabilidad horariaen suelo y roca para los sitios de instalación deestaciones acelerográficas, se elaboró un mapa deisoperiodos y se establecieron zonas de respuestadinámica similar, comparando los resultados con laszonificaciones previas realizadas y los accidentestopográficos. Además, se analizó la variabilidad de losregistros ante la presencia de tubificación subsuperficial,fenómeno habitual en la ciudad de Tunja, debido a losavanzados procesos de erosión de los depósitos, queha desestabilizado diversas construcciones. Losresultados obtenidos se usaron para determinar los sitiosdonde sería necesario instrumentar, y se trazaron pautaspara el proceso de zonificación definitivo de las ciudades,en la siguiente etapa del proyecto de microzonificación

  4. Computational solutions for non-isothermal, nonlinear magneto-convection in porous media with hall/ionslip currents and ohmic dissipation

    Directory of Open Access Journals (Sweden)

    O. Anwar Bég

    2016-03-01

    Full Text Available A theoretical and numerical study is presented to analyze the nonlinear, non-isothermal, magnetohydrodynamic (MHD free convection boundary layer flow and heat transfer in a non-Darcian, isotropic, homogenous porous medium, in the presence of Hall currents, Ionslip currents, viscous heating and Joule heating. A power-law variation is used for the temperature at the wall. The governing nonlinear coupled partial differential equations for momentum conservation in the x and z directions and heat conservation, in the flow regime are transformed from an (x, y, z coordinate system to a (ξ,η coordinate system in terms of dimensionless x-direction velocity (∂F/∂η and z-direction velocity (G and dimensionless temperature function (H under appropriate boundary conditions. Both Darcian and Forchheimer porous impedances are incorporated in both momentum equations. Computations are also provided for the variation of the x and z direction shear stress components and also local Nusselt number. Excellent correlation is achieved with a Nakamura tridiagonal finite difference scheme (NTM. The model finds applications in magnetic materials processing, MHD power generators and purification of crude oils.

  5. A study of atom zigzag chains on the surface of tungsten

    International Nuclear Information System (INIS)

    Audiffren, M.; Traimond, P.; Bardon, J.; Drechsler, M.

    1978-01-01

    Nishigaki and Nakamura have observed zigzag chains on the central (011) face of tungsten after field evaporation at T > 140 K. In this paper, a study of the formation, disappearance and structure of such chains is described. Tungsten tips of small radii down to 60 A were used. Chains of 3 to 9 spots, that are clearly visible, are found even at 90 K. Four different structure models of the zigzag chains are discussed, including the multibranch model proposed by the japanese authors. The interpretation of the experimental results shows fairly clearly that the real zigzag chain structure is a special non-dense structure. It must be formed by a local displacement of the tungsten adatoms in the field. Without the field, a zigzag chain is transformed into a two-dimensional cluster of the nearest neighbour atom by a small increase in temperature. If the field is reintroduced, the cluster can revert to the initial zigzag structure. The zigzag structure is interpreted as being caused by forces of repulsion between the atom dipoles. (Auth.)

  6. Una nueva evaluación de la Plaza de los Peregrinos de Pachacamac: aportes de la primera campaña 2003 del Proyecto Arqueológico Pachacamac

    Directory of Open Access Journals (Sweden)

    2004-01-01

    Full Text Available UNE NOUVELLE EVALUATION DE LA PLACE DES PELERINS DE PACHACAMAC. APPORT DE LA PREMIERE CAMPAGNE 2003 DU PROJET ARCHEOLOGIQUE PACHACAMAC. Entre les mois de juin et août 2003, le Projet Archéologique Pachacamac, co-dirigé par Izumi Shimada, Rafael Segura Llanos et María Rostworowski de Diez Canseco, a mené sa première campagne de terrain dans le cadre d'un programme de recherche à long terme. Ce projet interdisciplinaire et international a comme objectif principal l'étude des fondations sociales et du contexte naturel du celèbre site de Pachacamac. L'un des objectifs spécifiques de nos travaux en 2003 a été de définir la localisation et l'extension des zones résidentielles au cours du temps, ce grâce a un radar de pénétration des sols et à des fouilles de sondage. Dans cet essai, nous présentons les résultats les plus importants de ces interventions sur la Place des Pèlerins, plus précisement un secteur proche de l'Ushnu inca. Parmi les divers niveaux d'occupation Ychsma qui ont été détecté, certains ont plus particulièrement attiré notre attention, car ils sont associés à des épisodes récurrents de vénération de jarres en céramique, chacune insérée dans des constructions d'adobes ou des enceintes en pierres soigneusement élaborées. En termes généraux, il nous paraît que les données obtenues représentent une opportunité nouvelle de reviser nos conceptions actuelles de la zone considérée comme sacrée, à la lumière de 1 la découverte de diverses offrandes, denses et superposées, associées à des structures en canne de joncs et adobes, également superposées mais spatialement differenciées et 2 la manifestation d'une série de changements importants dans la nature de l'utilisation de la zone au cours du temps. Durante los meses de junio a agosto del año 2003, el Proyecto Arqueológico Pachacamac, bajo la co-dirección de Izumi Shimada, Rafael Segura Llanos y María Rostworowski de Diez Canseco

  7. Control rod drive mechanism

    International Nuclear Information System (INIS)

    Mizuno, Katsuyuki.

    1976-01-01

    Object: To restrict the reduction in performance due to stress corrosion cracks by making use of condensate produced in a turbine steam condenser. Structure: Water produced in a turbine steam condenser is forced into a condensed water desalting unit by low pressure condensate pump. The condensate is purified and then forced by a high pressure condensate pump into a feedwater heater for heating before it is returned to the reactor by a feedwater pump. Part of the condensate issuing from the condensate desalting unit is branched from the remaining portion at a point upstream the pump and is withdrawn into a control rod drive water pump after passing through a motordriven bypass valve, an orifice and a condenser water level control valve, is pressurized in the control rod drive water desalting unit and supplied to a control rod drive water pressure system. The control rod is vertically moved by the valve operation of the water pressure system. Since water of high oxygen concentration does not enter during normal operation, it is possible to prevent the stress cracking of the stainless steel apparatus. (Nakamura, S.)

  8. An NMR study of Pr0.5Ca0.5Mn1-xGaxO3 (x = 0 and 0.03)

    International Nuclear Information System (INIS)

    Oates, C.J.; Sikora, M.; Zajac, D.; Rybicki, D.; Kapusta, Cz.; Riedi, P.C.; Martin, C.; Yaicle, M.; Maignan, A.

    2004-01-01

    An NMR study of polycrystalline Pr 0. 5Ca 0.5 Mn 1-x Ga x O 3 (x = 0 and 0.03) at 3 K is presented. Zero field spin echo spectra of the Ga doped compound consist of an overlapping 6: 9 ,71 Ga signal at 74 MHz (hyperfine field of 5.3 T), a 55 Mn double exchange line at 375 MHz (35.5 T) and a weak Mn 3+ signal between 400 and 550 MHz. Measurements in an applied field show a step-like increase in the double exchange line intensity, which corresponds to an increase in the amount of the ferromagnetic metallic phase. This coincides with a step-like feature in the bulk magnetization measurements. The effect is similar to that in the previous field dependent 55 Mn NMR measurements of Pr 0.67 Ca 0.33 MnO 3 . At the demagnetized and remanent state, a variation of spin-spin relaxation time T 2 , across the 55 Mn line, due to a Suhl-Nakamura interaction is observed, which suggests that the ferromagnetic metallic double exchange regions, at liquid helium temperatures, are at least 4 nm in size

  9. Inflammatory myoglandular colorectal polyps: a series of seven cases and review of literature.

    Science.gov (United States)

    Becheanu, G; Gheorghe, C; Dumbravă, M; Serban-Barbu, V; Diculescu, M

    2011-01-01

    Inflammatory myoglandular polyp is an unusual but distinct, non-neoplastic type of colorectal polyp, commonly with a distal localization at the recto-sigmoidian level. It was first described in 1992 by Nakamura and his colleagues and it is considered to have few particular histological features. We report a series of seven cases (two male and five female patients) of myoglandular polyps with different localization from 15 to 40 cm from anus. Only four out of seven cases presented with rectal bleeding, the others polyps we incidentally discovered. The polyps varied between 4 and 30 mm in the maximum diameter. Grossly, they had firm consistency and smooth reddish surface. Histological examination of the specimens revealed hyperplastic glands with occasional cystic dilatation, proliferation of smooth muscle with no regular distribution, a variable amount of granulation tissue (usually minimal) and no evidence of epithelial dysplasia. All the lesions were removed endoscopically without any complications. Inflammatory myoglandular polyps are distinct histopathological entities, with insufficiently investigated pathogenesis that can include local trauma, mucosal prolapse or ischemia. Being benign they can be removed endoscopically, surgical treatment being reserved in selected cases.

  10. Apparatus for inspecting a irradiated nuclear fuel rod

    International Nuclear Information System (INIS)

    Saura, Hideaki; Yonemura, Eizo.

    1975-01-01

    Object: To increase safety and inspection efficiency by operating irradiated fuel rods, which are accommodated in a water-filled pool after being taken out from the reactor. Structure: When making inspection of irradiated fuel rods, particularly the cladding tube thereof, a fuel box which stores irradiated fuel rods in a water pool is secured to a securement mechanism with slime removal apparatus and inspection apparatus on either side capable of being vertically moved, and it is then stopped at a water depth of about 2 meters. When the lid of the box is opened, irradiated fuel rods are taken out with gripping means and then secured together with the gripping means to an operation base provided on the outside of the pool. Thereafter, the box is lowered by operating pedals on the operation base to completely pull out the irradiated fuel rods from the box, and the irradiated fuel rods are then horizontally moved and then held in a suspended state. Next a slime removal apparatus in raised by operating pedals and an inspection element assembly are progressively raised for inspection of the state of the cladding tube of each fuel rod after removal of slime therefrom. (Nakamura, S.)

  11. Authors' response to letter to the editor: "Bar velocities capable of optimising the muscle power in strength-power exercises" by Loturco, Pereira, Abad, Tabares, Moraes, Kobal, Kitamura & Nakamura (2017).

    Science.gov (United States)

    Loturco, Irineu

    2018-07-01

    Our study in the Journal of Sports Sciences was originally designed to test whether the bar-velocity is a precise indicator of the power training intensity (i.e., optimum loads) in different exercises commonly included in athletes' training programs. Furthermore, we presented secondary findings, related to the actual results obtained in our assessments. As a cross-sectional study with clear objectives, we focused on discussing issues and applications pertaining to neuromuscular training interventions, such as: (1) describing the advantages of using bar-velocities to control the power training intensity, (2) defining a range of loads capable of maximizing the power production in certain ballistic and traditional exercises, and (3) revealing the differences between these exercises and the respective implications for training. Fundamentally, we did not produce a mechanistic investigation and were very accurate and consistent in reporting our data, collected under rigorous and well-established experimental conditions. Here we provide our point-by-point comments to the concerns raised in the "Letter to the Editor", along with some theoretical explanations about the secondary findings reported by the authors of the Letter. To better understand the nature and purposes of our experiment, we also present a series of practical examples and review previous investigations involving the "bar-power" approach.

  12. Letter to the editor concerning the article "Bar velocities capable of optimising the muscle power in strength-power exercises" by Loturco, Pereira, Abad, Tabares, Moraes, Kobal, Kitamura & Nakamura (2017).

    Science.gov (United States)

    Jaric, Slobodan; Garcia Ramos, Amador

    2018-05-01

    Loturco and co-workers (2017) recently published data in the Journal of Sports Sciences to present the optimum loading magnitudes regarding the maximization of the "mean propulsive power" of the leg and arm muscles. Among the most important findings were that (1) the recorded power in the squat and squat jump exercises was markedly low, (2) the optimum external load that maximized the power in the same exercises was close to 100% of body weight, while (3) the ballistic bench press throw revealed smaller power than the regular bench press typically performed with relatively low level of muscle activation towards the end of the propulsive lifting phase. The findings are either counter-intuitive, or contradict the literature findings, or both, and we believe that they originate from apparent methodological flaws. The first one is neglecting the force acting against the body segments moved together with the external load that is particularly high in squat exercises. The second one is an erroneous calculation of the propulsive phase that included a part of the bar's flight time. Both of these methodological flaws are frequent in the literature and could be associated with the improper use and calculation of variables when utilizing linear position transducers.

  13. Population pharmacokinetics of olprinone in healthy male volunteers

    Directory of Open Access Journals (Sweden)

    Kunisawa T

    2014-03-01

    Full Text Available Takayuki Kunisawa,1 Hidefumi Kasai,2 Makoto Suda,2 Manabu Yoshimura,3 Ami Sugawara,3 Yuki Izumi,3 Takafumi Iida,3 Atsushi Kurosawa,3 Hiroshi Iwasaki3 1Surgical Operation Department, Asahikawa Medical University Hospital, Hokkaido, Japan; 2Clinical Study Management Division, Bell Medical Solutions Inc, Tokyo, Japan; 3Department of Anesthesiology and Critical Care Medicine, Asahikawa Medical University, Hokkaido, Japan Background: Olprinone decreases the cardiac preload and/or afterload because of its vasodilatory effect and increases myocardial contractility by inhibiting phosphodiesterase III. Purpose: The objective of this study was to characterize the population pharmacokinetics of olprinone after a single continuous infusion in healthy male volunteers. Methods: We used 500 plasma concentration data points collected from nine healthy male volunteers for the study. The population pharmacokinetic analysis was performed using the nonlinear mixed effect model (NONMEM® software. Results: The time course of plasma concentration of olprinone was best described using a two-compartment model. The final pharmacokinetic parameters were total clearance (7.37 mL/minute/kg, distribution volume of the central compartment (134 mL/kg, intercompartmental clearance (7.75 mL/minute/kg, and distribution volume of the peripheral compartment (275 mL/kg. The interindividual variability in the total clearance was 12.4%, and the residual error variability (exponential and additive were 22.2% and 0.129 (standard deviation. The final pharmacokinetic model was assessed using a bootstrap method and visual predictive check. Conclusion: We developed a population pharmacokinetic model of olprinone in healthy male adults. The bootstrap method and visual predictive check showed that this model was appropriate. Our results might be used to develop the population pharmacokinetic model in patients. Keywords: phosphodiesterase III inhibitor, men, pharmacokinetic model

  14. Long-term effect of galantamine on cognitive function in patients with Alzheimer’s disease versus a simulated disease trajectory: an observational study in the clinical setting

    Directory of Open Access Journals (Sweden)

    Nakagawa R

    2017-04-01

    Full Text Available Ryoko Nakagawa,1 Takashi Ohnishi,1 Hisanori Kobayashi,1 Toshio Yamaoka,2 Tsutomu Yajima,3 Ai Tanimura,4 Toshiya Kato,4 Kazutake Yoshizawa1 1Evidence Generation Department, Medical Affairs Division, 2Clinical Data Management Department, R&D Division, 3Biostatistics Department, Quantitative Science Division, 4Drug Surveillance Department, R&D Division, Janssen Pharmaceutical K.K., Tokyo, Japan Background: Long-term maintenance of cognitive function is an important goal of treatment for Alzheimer’s disease (AD, but evidence about the long-term efficacy of cholinesterase inhibitors is sparse. To evaluate the long-term efficacy and safety of galantamine for AD in routine clinical practice, we conducted a 72-week post-marketing surveillance study. The effect of galantamine on cognitive function was estimated in comparison with a simulated disease trajectory. Patients and methods: Patients with mild-to-moderate AD received flexible dosing of galantamine (16–24 mg/day during this study. Cognitive function was assessed by the mini mental state examination (MMSE and the clinical status was determined by the Clinical Global Impression-Improvement (CGI-I. Changes of the MMSE score without treatment were estimated in each patient using Mendiondo’s model. Generalized linear mixed model analysis was performed to compare the simulated MMSE scores with the actual scores. Results: Of the 661 patients who were enrolled, 642 were evaluable for safety and 554 were assessed for efficacy. The discontinuation rate was 46.73%. Cognitive decline indicated by the mean change of actual MMSE scores was significantly smaller than the simulated decline. Individual analysis demonstrated that >70% of patients had better actual MMSE scores than their simulated scores. Significant improvement of CGI-I was also observed during the observation period. Adverse events occurred in 28.5% of patients and were serious in 8.41%. The reported events generally corresponded with the

  15. Air-insufflated high-definition dacryoendoscopy yields significantly better image quality than conventional dacryoendoscopy

    Directory of Open Access Journals (Sweden)

    Sasaki T

    2017-08-01

    Full Text Available Tsugihisa Sasaki,1 Tsutomu Sounou,2 Hideki Tsuji,3 Kazuhisa Sugiyama4 1Sasaki Eye Clinic, Mikuni, Sakai, 2Department of Ophthalmology, Keiju Kanazawa Hospital, 3Department of Ophthalmology, Cancer Institute Hospital, 4Department of Ophthalmology and Visual Science, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan Purpose: To facilitate the analysis of lacrimal conditions, we utilized high-definition dacryoendoscopy (HDD and undertook observations with a pressure-controlled air-insufflation system. We report the safety and performance of HDD.Methods: In this retrospective, non-randomized clinical trial, 46 patients (14 males and 32 females; age range 39–91 years; mean age ± SD 70.3±12.0 years who had lacrimal disorders were examined with HDD and conventional dacryoendoscopy (CD. The high-definition dacryoendoscope had 15,000 picture element image fibers and an advanced objective lens. Its outer diameter was 0.9–1.2 mm. Air insufflation was controlled at 0–20 kPa with a digital manometer-based pressure-controlled air-insufflation system to evaluate the quality of the image. The HDD had an air/saline irrigation channel between the outer sheath (outer diameter =1.2 mm and the metal inner sheath of the endoscope. We used it and the CD in air, saline, and diluted milk saline with and without manual irrigation to quantitatively evaluate the effect of air pressure and saline irrigation on image quality.Results: In vivo, the most significant improvement in image quality was demonstrated with air-insufflated (5–15 kPa HDD, as compared with saline-irrigated HDD and saline-irrigated CD. No emphysema or damage was noted under observation with HDD. In vitro, no significant difference was demonstrated between air-insufflated HDD and saline-irrigated HDD. In vitro, the image quality of air-insufflated HDD was significantly improved as compared with that of saline-irrigated CD.Conclusion: Pressure-controlled (5–15 kPa air

  16. Development of a novel disposable lid speculum with a drape

    Directory of Open Access Journals (Sweden)

    Urano T

    2013-08-01

    Full Text Available Toru Urano,1 Masataka Kasaoka,1 Ryoji Yamakawa,1 YukihikoTamai,2 Shoichiro Nakamura21Department of Ophthalmology, Kurume University School of Medicine, Kurume, Japan; 2Hakko Co, Ltd, Nagano, JapanPurpose: To evaluate the clinical use of a newly-developed disposable lid speculum with a drape.Methods: LiDrape® is a cylindrical device that consists of two flexible rings of polyacetal resin with a transparent elastic silicone sheet attached to the rings. The novel device holds the eyelids between the rings, and a hole in the center of the device provides a surgical field. We used the novel device in cataract surgery (75 eyes, glaucoma surgery (eleven eyes, vitrectomy (ten eyes, and intravitreal injection (six eyes and evaluated its clinical efficacy.Results: The LiDrape was easy to attach and detach. The novel device was not detached from the eye during surgery. No eyelashes or secretions from the meibomian glands were seen in the surgical field, and the drape provided a sufficient surgical field.Conclusions: The LiDrape functions as a lid speculum as well as a drape. Our results showed that the novel device is useful for ocular surgeries.Keywords: LiDrape, lid speculum, drape, endophthalmitis

  17. βp-collapse-induced vertical displacement event in high βp tokamak disruption

    International Nuclear Information System (INIS)

    Nakamura, Y.; Yoshino, R.; Pomphrey, N.; Jardin, S.C.

    1996-01-01

    Extremely fast vertical displacement events (VDEs) induced by a strong β p collapse were found in a vertically elongated (κ ∼ 1.5), high β p (β p ∼ 1.7) tokamak with a resistive shell through computer simulations using the tokamak simulation code. Although the plasma current quench which has been shown to be the prime cause of VDEs in a relatively low β p tokamak (β p ∼ 0.2) (Nakamura Y et al 1996 Nucl. Fusion 36 643), was not observed during the VDE evolution, the observed growth rate of VDEs was almost five times (γ ∼ 655 s -1 ) faster than the growth rate of the usual positional instability (γ ∼ 149 s -1 ). The essential mechanism of the β p -collapse-induced VDE was clarified to be the intense enhancement of positional instability due to a large and sudden degradation of the magnetic field decay n-index in addition to the significant destabilization due to a reduction in the stability index n s . The radial shift of the magnetic axis caused by the β p collapse induces eddy currents on the resistive shell, and these eddy currents produce a large degradation of the n-index. (author)

  18. Laser mass spectrometry for DNA fingerprinting for forensic applications

    Science.gov (United States)

    Chen, C. H. Winston; Tang, Kai; Taranenko, N. I.; Allman, S. L.; Ch'ang, L. Y.

    1994-10-01

    The application of DNA fingerprinting has become very broad in forensic analysis, patient identification, diagnostic medicine, and wildlife poaching, since every individual's DNA structure is identical within all tissues oftheir body. DNA fingerprinting was initiated by the use of restriction fragment length polymorphisms (RFLP). In 1987, Nakamura et aL2 found that a variable number of tandem repeats (VNTR) often occurred in the alleles. The probability of different individuals having the same number of tandem repeats in several different alleles is very low. Thus, the identification of VNTR from genomic DNA became a very reliable method for identification of individuals. Take the Huntington gene as an example, there are CAG trinucleotide repeats. For normal people, the number of CAG repeats is usually between 10 and 40. Since people have chromosomes in pairs, the possibility oftwo individuals having the same VNTR in the Huntington gene is less than one percent, ifwe assume equal distribution for various repeats. When several allels containing VNTR are analyzed for the number of repeats, the possibility of two individuals being exactly identical becomes very unlikely. Thus, DNA fingerprinting is a reliable tool for forensic analysis. In DNA fingerprinting, knowledge of the sequence of tandem repeats and restriction endornuclease sites can provide the basis for identification.

  19. Einstein model for elementary particles

    International Nuclear Information System (INIS)

    Sharma, N.K.

    1975-01-01

    A group theoretical model unifying a space-time group (E) and an internal symmetry group (I) for strongly interacting particles is worked out. The space-time group is the one that pertains to the group of motions of static Einstein cosmological model implying the symmetry of the group E = O 4 logical operation of multiplication R. With the use of Gueret and Vigier prescription, the left coset R logical operation of multiplication O 4 is identified with the internal symmetry group I = U 1 β logical operation of multiplication (SU(2) logical operation of multiplication SU(2)) contains SU(4). The complete dynamical group (D) is then found to be D = E logical operation of multiplication I = (O logical operation of multiplication R) logical operation of multiplication U 1 β logical operation of multiplication (SU(2) logical operation of multiplication SU(2) contains SO(4,2). Physically useful representations of the space-time group (E) are worked out by solving the eigenvalue problem of Laplace-Beltmi operator. The internal quantum numbers are prescribed in accordance with the SU(2) logical operation of multiplication SU(2) model of Nakamura and Sato. A general mass formula is derived and its use for known baryons and mesons is discussed. (author)

  20. Towards a Detailed Seismic Structure of the Valley of Mexico's Xochimilco Lake Zone.

    Science.gov (United States)

    Rabade, S.; Sanchez-Sanchez, J.; Ayala Hernandez, M.; Macias, M. A.; Aguilar Calderon, L. A.; Alcántara, L.; Almora Mata, D.; Castro Parra, G.; Delgado, R.; Leonardo Suárez, M.; Molina Avila, I.; Mora, A.; Perez-Yanez, C.; Ruiz, A. L.; Sandoval, H.; Torres Noguez, M.; Vazquez Larquet, R.; Velasco Miranda, J. M.; Aguirre, J.; Ramirez-Guzmán, L.

    2017-12-01

    Six centuries of gradual, intentional sediment filling in the Xochimilco Lake Zone have drastically reduced the size of the lake. The basin structure and the lake's clay limits and thickness are poorly constrained, and yet, essential to explain the city's anomalous ground motion. Therefore, we conducted an experiment to define the 3D velocity model of Mexico's capital; the CDMX-E3D. The initial phase involved the deployment of a moving set of 18-broadband stations with an interstation distance of 500m over a period of 19 weeks. We collected the data and analyzed the results for the Xochimilco Lake Zone using H/V Spectral Ratios (Nakamura, 1989), which provided an improved fundamental period map of the region. Results show that periods in the former lake zone have larger variability than values previously estimated. In order to obtain group velocity maps at different periods, we estimated Green's functions from ambient noise cross-correlations following standard methodologies to invert Rayleigh wave travel times (Bensen et al., 2007). Preliminary result show very low-velocity zones (100 m/s) and thick sediment layers in most of the former Xochimilco Lake area. This Project was funded by the Secretaria de Ciencia, Tecnología e Innovación (SECITI) of Mexico City. Project SECITI/073/2016.

  1. Development of seismic analysis method considered FSI effect on a neutron reflector for APWR reactor internals

    Energy Technology Data Exchange (ETDEWEB)

    Hideyuki, Morika; Tomomichi, Nakamura [Mitsubishi Heavy Industries Ltd., Takasago R and D Center, Hyogo (Japan); Toshio, Ichikawa; Kazuo, Hirota; Hiroyuki, Murakiso [Mitsubishi Heavy Industries Ltd., Kobe Shipyard and Machinery Works, Hyogo, Kobe (Japan); Minoru, Murota [Japan Atomic Power Co., Tokyo (Japan)

    2004-07-01

    A Neutron Reflector (NR) is a new structure designed for improving the structure reliability of Advanced Pressurized Water Reactors (APWR,). The NR is placed in a narrow gap between the NR and a Core Barrel (CB). In the case of a structure surrounded by liquid in a narrow gap, the added fluid mass and the damping increases compared with in the air. This effect is famous for Fluid-Structure Interaction effect (FSI effect) in the narrow gap and it depends on the vibration displacement of the structure. A new method to estimate the added fluid damping for this case has been introduced by some of the authors in 2001, which is based on a narrow passage flow theory (Morita et al., 2001). Following this theory, a vibration test was performed to assess the appropriateness of the analysis method employed to measure the response of the NR during an earthquake (Nakamura et al., 2002). In this paper, results of a model test are shown comparing the data with the calculated ones based on the new analysis method that is combined the above method with the ANSYS computer code. As a result, a new seismic analysis method using the above theory was developed. The analytical results are in good agreement with the test results. (authors)

  2. Game Demands of Seven-A-Side Soccer in Young Players.

    Science.gov (United States)

    Barbero-Alvarez, José C; Gómez-López, Maite; Castagna, Carlo; Barbero-Alvarez, Verónica; Romero, David V; Blanchfield, Anthony W; Nakamura, Fábio Y

    2017-07-01

    Barbero-Alvarez, JC, Gómez-López, M, Castagna, C, Barbero-Alvarez, V, Romero, DV, Blanchfield, AW, and Nakamura, FY. Game demands of seven-a-side soccer in young players. J Strength Cond Res 31(7): 1771-1779, 2017-The aim of this study was to examine the activity patterns and physiological demands of 7-a-side youth soccer matches across 2 chronological age categories (U12 and U14). Twenty-two soccer players of a national youth soccer academy were investigated. Players of each age category performed 2 training matches (2 × 25 minutes) and were monitored by global positioning system and heart rate monitor units. Players of both categories covered similar total distance (5,348 ± 307 m), at similar mean heart rate values (86 ± 4% of maximum). However, the number of high-intensity runs (82.5 ± 17.4 vs. 69.7 ± 15.2) and total distance covered during sprints (264 ± 207 vs. 128 ± 74 m) were significantly (p ≤ 0.05) higher in U14 compared with U12. The results suggest a highly demanding nature of 7-a-side soccer for skilled players, with physical maturity possibly influencing the match-related high-intensity performance at these ages.

  3. Disaster risk management in prospect mining area Blitar district, East Java, using microtremor analysis and ANP (analytical network processing) approach

    Energy Technology Data Exchange (ETDEWEB)

    Parwatiningtyas, Diyan, E-mail: diane.tyas@gmail.com, E-mail: erlinunindra@gmail.com; Ambarsari, Erlin Windia, E-mail: diane.tyas@gmail.com, E-mail: erlinunindra@gmail.com; Marlina, Dwi, E-mail: diane.tyas@gmail.com, E-mail: erlinunindra@gmail.com; Wiratomo, Yogi, E-mail: diane.tyas@gmail.com, E-mail: erlinunindra@gmail.com [Department of Physics, Faculty of Engineering, Mathematics and Natural Sciences, Indraprasta PGRI University, Nangka Street No. 58C Tanjung Barat, South Jakarta (Indonesia)

    2014-03-24

    Indonesia has a wealth of natural assets is so large to be managed and utilized, either from its own local government and local communities, especially in the mining sector. However, mining activities can change the state of the surface layer of the earth that have a high impact disaster risk. This could threaten the safety and disrupt human life, environmental damage, loss of property, and the psychological impact, sulking to the rule of law no 24 of 2007. That's why we strive to manage and minimize the risk of mine disasters in the region, how to use the method of calculation of Amplification Factor (AF) from the analysis based microtremor sulking Kanai and Nakamura, and decision systems were tested by analysis of ANP. Based on the amplification factor and Analytical Network Processing (ANP) obtained, some points showed instability in the surface layer of a mining area include the site of the TP-7, TP-8, TP-9, TP-10, (Birowo2). If in terms of structure, location indicated unstable due to have a sloping surface layer, resulting in the occurrence of landslides and earthquake risk is high. In the meantime, other areas of the mine site can be said to be a stable area.

  4. An investigation on damaged buildings in Ranau due the 2015 Sabah earthquake

    Science.gov (United States)

    Lim, Yang Soh; Tan, Jun Pin; Chiew, Lerk Qing; Chang, Wai Hoe; Lau, Tze Liang

    2017-10-01

    A magnitude 5.9 earthquake struck near Ranau district in Sabah, Malaysia on June 5, 2015. The epicenter was located 14 km from Ranau. Various buildings were damaged by the earthquake. This paper discusses the extent of the destruction to two severely damaged structures in Ranau. An assessment of damaged buildings in Ranau Hospital using microtremor data was conducted after the earthquake event. The building consists of two identical blocks with similar soft-story structural forms. Two microtremor observations were carried out before and after the repair work. The predominant frequencies of the damaged buildings were determined by using the Nakamura's H/V method. Based on the assumption that both identical blocks of building in Ranau Hospital have similar predominant frequencies due to the same structural design and construction quality, results show that B block of Ranau Hospital suffered more damage compared with another block of the building. The predominant frequency of B block is 10% lower than that of A Block. Results obtained are consistent with the observed building performance during the site reconnaissance. The predominant frequency of both buildings measured after the repair work shows 11% to 21% increment, which implies that the lateral stiffness of both buildings has been improved.

  5. DETERMINACIÓN DE PROPIEDADES DINÁMICAS DEL SUELO EN LA POBLACIÓN DE CUMANACOA, REALIZADOS PARA MICROZONIFICACIÓN SÍSMICA, 2006 I DETERMINATION OF DYNAMIC PROPERTIES OF THE SOIL IN THE CUMANACOA LOCALITY, MADE FOR SEISMIC MICROZONATION, 2006

    Directory of Open Access Journals (Sweden)

    Francisco Antonio Bonive Aguilera

    2014-02-01

    Full Text Available The city of Cumanacoa is considered an historical patrimony of the northeastern region of Venezuela, which in spite of its relative distance (From where?, can be stricken by an earthquake originated in the fault zone of El Pilar. Using the technique of Nakamura (Horizontal/Vertical it was determined that the locality has fundamental periods between 0.4 and 1 s, with amplifications between 2 and 5.5. The vulnerability index is commonly smaller than 18, which turns it into a relatively safe region for amplifications in important buildings. The critical number of cycles was always larger than 400, which certifies the conditions of all the measures of microtremors. The standardized sedimentary thickness shows a brief cortical structure which is dominated (60% by areas with half the thickness of the deepest sediment; this affects an area close to 40% of the studied surface. The spatial distribution shows the expected correlation between the fundamental period and the thickness, with a well-defined area of increased sedimentary thickness towards the Centre of the town. The amplification displays a different space distribution demonstrating a possible orientation NNE-SSO. The vulnerability index presents its highest values towards the periphery of the town, specially in the South Central area.

  6. Evaluation and investigation of regional cerebral blood flow by 1 point arterial blood collection method using 99mTc-ECD. Intravenous injection for 4 minutes with constant speed

    International Nuclear Information System (INIS)

    Itoh, Takeo; Shibata, Kazuhiro; Sudoh, Hideaki; Tanaka, Masato; Itoh, Kenjiro; Ueno, Yasushi

    1998-01-01

    Regional cerebral blood flow (rCBF) was measured using a 99m Tc-ECD through the 4-min constant intravenous infusion/one point arterial blood sampling method, proposed by Nakagawara et al. of Nakamura Memorial Hospital, and 133Xenon ( 133 Xe)-SPECT was performed on the same subjects to investigate the reproducibility of this method. We also determined whether cerebral blood flow (CBF) could be measured on the day of blood sampling through dilution of the obtained blood because it was difficult to measure the radioactivity in the blood on the day of blood sampling by this method. More, we investigated fixation of an octanol extraction rate and the substitution of venous blood for arterial blood in this method. The results revealed that CBF measured by this method with a 99m Tc-ECD were closely correlated to those measured by 133 Xe-SPECT, indicating the reliability as a method of measuring CBF. rCBF could be measured on the day of blood sampling through appropriate dilution of the obtained arterial blood. Octanol extraction rates were almost constant, indicating possible omission of cumbersome extraction procedure by fixation. However, the substitution of venous blood for arterial blood showed no correlation under the study system examined. (author)

  7. Analysis of hepatic vein variations in healthy people with 64-slice spiral CT

    International Nuclear Information System (INIS)

    Zhang Rong; Li Yong; Shen Jun; Zeng Weike; Li Jieting; Huang Suiqiao; Liang Biling; Liu Chao

    2007-01-01

    Objective: To analyze variations of hepatic vein in healthy people with 64-slice spiral CT. Methods: Seventy-five healthy subjects underwent multi-slice spiral computed (MSCT) hepatic venography. The anatomy of the junction of the hepatic veins with the inferior vena cava and the intrahepatic drainage territory of the hepatic veins and tributaries were evaluated. The hepatic veins were classified according to three anatomic classification (Nakamura's, Marcos's and Kawasaki's classification) methods respectively. Results: There was a common trunk of the middle and left hepatic veins before joining the IVC in 86.7% (65/75)of the cases. In 13.3% (10/75)of the cases, the three main hepatic veins joined the IVC separately. The ratios of Nakamma's classification type A, B, C of hepatic veins were 49.4% (37/75), 37.3% (28/75), and 13.3% (10/75) respectively. The ratios of Marcos's classification type A, B, C of hepatic veins were 56.0% (42/75), 24.0% (18/75), and 20.0% (15/75) respectively. The ratios of Kawasaki's classification type I, II of hepatic vein were 40.0% (30/75) and 60.0% (45/75). Conclusion: Multi-slice spiral CT hepatic venography can provide visualization of peripheral hepatic venous branches in details. (authors)

  8. The effect of thermal loads on buckling strength of cylindrical shells

    International Nuclear Information System (INIS)

    Kawamoto, Y.; Kodama, T.; Matsuura, S.

    1993-01-01

    Nuclear power plant components must be designed taking account of strong seismic loads in countries with frequent earthquakes like Japan. When designing such thin-walled shell components as a main vessel of a fast breeder reactor (FBR), one should consider the possibility that buckling might occur. In Japan, a series of buckling research has been conducted under contract with the Ministry of International Trade and Industry to develop the aseismic design method for a demonstration FBR. This study has been also done as a part of them. The problem of thermal loads on buckling strength is one of the important problems in the buckling research for FBR because axial temperature gradient is produced in a main vessel and the significant thermal stress is shown. Some studies on the effect of thermal loads on buckling strength were carried out (Brochard, 1987), (Nakamura, 1987), but its effect in the actual vessel has not been evaluated quantitatively. We have already reported the effect of thermal loads on buckling strength of a pool-type reactor vessel. (Kawamoto ,1989) In this paper, we focus on a loop-type reactor vessel and investigate the effect of thermal loads accompanying with axial temperature change near the sodium level. And the reduction of buckling strength due to the thermal loads is quantitatively evaluated

  9. Restoration and Reexamination of Apollo Lunar Dust Detector Data from Original Telemetry Files

    Science.gov (United States)

    McBride, M. J.; Williams, David R.; Hills, H. Kent

    2012-01-01

    We are recovering the original telemetry (Figure I) from the Apollo Dust, Thermal, Radiation Environment Monitor (DTREM) experiment, more commonly known as the Dust Detector, and producing full time resolution (54 second) data sets for release through the Planetary Data System (PDS). The primary objective of the experiment was to evaluate the effect of dust deposition, temperature, and radiation damage on solar cells on the lunar surface. The monitor was a small box consisting of three solar cells and thermistors mounted on the ALSEP (Apollo Lunar Surface Experiments Package) central station. The Dust Detector was carried on Apollo's 11, 12, 14 and 15. The Apollo 11 DTREM was powered by solar cells and only operated for a few months as planned. The Apollo 12, 14, and 15 detectors operated for 5 to 7 years, returning data every 54 seconds, consisting of voltage outputs from the three solar cells and temperatures measured by the three thermistors. The telemetry was received at ground stations and held on the Apollo Housekeeping (known as "Word 33") tapes. made available to the National Space Science Data Center (NSSDC) by Yosio Nakamura (University of Texas Institute for Geophysics). We have converted selected parts of the telemetry into uncalibrated and calibrated output voltages and temperatures.

  10. Disaster risk management in prospect mining area Blitar district, East Java, using microtremor analysis and ANP (analytical network processing) approach

    International Nuclear Information System (INIS)

    Parwatiningtyas, Diyan; Ambarsari, Erlin Windia; Marlina, Dwi; Wiratomo, Yogi

    2014-01-01

    Indonesia has a wealth of natural assets is so large to be managed and utilized, either from its own local government and local communities, especially in the mining sector. However, mining activities can change the state of the surface layer of the earth that have a high impact disaster risk. This could threaten the safety and disrupt human life, environmental damage, loss of property, and the psychological impact, sulking to the rule of law no 24 of 2007. That's why we strive to manage and minimize the risk of mine disasters in the region, how to use the method of calculation of Amplification Factor (AF) from the analysis based microtremor sulking Kanai and Nakamura, and decision systems were tested by analysis of ANP. Based on the amplification factor and Analytical Network Processing (ANP) obtained, some points showed instability in the surface layer of a mining area include the site of the TP-7, TP-8, TP-9, TP-10, (Birowo2). If in terms of structure, location indicated unstable due to have a sloping surface layer, resulting in the occurrence of landslides and earthquake risk is high. In the meantime, other areas of the mine site can be said to be a stable area

  11. Origin of adenocarcinoma in Barrett's esophagus: P53 and Ki67 expression and histopathologic background Origem do adenocarcinoma no esôfago de Barrett: bases histopathológicas e expressão dos genes p53 e Ki67

    Directory of Open Access Journals (Sweden)

    Sergio Szachnowicz

    2005-04-01

    Full Text Available Barrett's esophagus is the substitution of squamous epithelium of the distal esophagus by columnar epithelium. Intestinal metaplasia in Barrett's esophagus is considered to be the main risk factor for the development of adenocarcinoma. Diffuse adenocarcinoma and Barrett's esophagus without intestinal metaplasia are rare, and reports on the subject are scarce. PURPOSE AND METHOD: To estimate the prevalence of adenocarcinoma in 297 patients with Barrett's esophagus, during the period of 1990 to 2002, and in 13 patients undergoing surgery, to conduct detailed macroscopic and microscopic analysis, with performance of immunohistochemical tests for p53 and Ki67, correlating the type of tumor with its adjacent epithelium. RESULTS: In our patients with Barrett's esophagus, there was a prevalence of 5.7% of adenocarcinoma. The tumors developed only when the Barrett's esophagus segment was long (>3.0 cm. Tumors were located close to the squamous-columnar junction. The histological study revealed 2 patients (15.4% with Barrett's esophagus adjacent to a tumor with gastric metaplasia without the presence of intestinal metaplasia. Tumors were classified according to Nakamura's classification (23% differentiated pattern, and 77% undifferentiated pattern and to Lauren's classification (61% intestinal and 39% diffuse. The difference is due to the migration of microtubular and foveolar tumors of undifferentiated (gastric pattern in Nakamuras classification to the Lauren's intestinal type. The immunohistochemical test for Ki67 was strongly positive in all the patients, thus evidencing intense cell proliferation in both the columnar epithelium and tumor. Expression of p53 was negative in 67% of the adjacent columnar epithelia and 42% of the tumors, without any correlation between the tissue types. CONCLUSION: Adenocarcinoma develops from mixed columnar epithelium, either intestinal or gastric, showing both the gastric and the intestinal patterns; thus, tumors can

  12. Task-based Language Learning in Bilingual Montessori Elementary Schools: Customizing Foreign Language Learning and Promoting L2 Speaking Skills

    Directory of Open Access Journals (Sweden)

    Jana Winnefeld

    2012-01-01

    Full Text Available Foreign language learning has been a part of German elementary schools for several years now. Montessori schools focusing on individual learning, i.e. mostly independent from the teacher and based on auto-education, interest, and free choice, are also asked to teach an L2. The original lack of a concept of L2 learning for this environment has brought forth different approaches. Bilingual education seems to be feasible and applicable in Montessori education. The downside to this is that even in a bilingual classroom the Montessori way of learning may not allow for very much oral production of the foreign language. The role of L2 production (cf. Swain 1985, 1995, 2005 for language acquisition has been theoretically claimed and empirically investigated. Output can have a positive influence on L2 learning (cf. e.g. Izumi 2002, Keck et al. 2006. This also applies to interaction (cf. Long 1996, where negotiation of meaning and modified output are factors supporting L2 development (cf. e.g. de la Fuente 2002, McDonough 2005. Task-based Language Learning (TBLL presents itself as one way to promote oral language production and to provide opportunities for meaning-negotiation. Especially tasks with required information exchange and a closed outcome have been shown to be beneficial for the elicitation of negotiation of meaning and modified output. This paper argues that TBLL is a promising approach for the facilitation of L2 production and thus the development of speaking skills in a Montessori context. It also hypothesizes that TBLL can be implemented in a bilingual Montessori environment while still making the Montessori way of learning possible. Different tasks on various topics, examples of which are presented in this article, can lay the foundation for this. Offering such tasks in a bilingual Montessori elementary classroom promises to foster language production and the use of communication strategies like negotiation of meaning, both being

  13. Men presenting with prostate-specific antigen (PSA) values of over 100 ng/mL.

    Science.gov (United States)

    Ang, Mann; Rajcic, Branimir; Foreman, Darren; Moretti, Kim; O'Callaghan, Michael E

    2016-04-01

    To investigate overall survival and prostate cancer-specific mortality in men with prostate cancer presenting with a PSA level PSA level extracted from the South Australian Prostate Cancer Clinical Outcomes Collaborative (SA-PCCOC) database. Men included were diagnosed between January 1998 and August 2013. Patients were divided into groups according to diagnostic PSA level: 500 ng/mL. Outcomes measured include overall survival and prostate cancer-specific mortality. Clinical stage, Gleason score and the presence of bony metastasis was evaluated to determine if they were prognostic factors in patients with PSA over 100 at diagnosis. Cox proportional hazards and competing risks regression were used to model overall survival and prostate cancer-specific mortality outcomes respectively. Of this cohort, 241 patients (4.2%) had a diagnostic PSA level >100 ng/mL. Patients with PSA >100 ng/mL have a significant reduction in five (29.1% vs 62.5% vs 87%) and ten-year (18.2% vs 36.7% vs 70.7%) overall survival when compared to men with diagnostic PSA 20-100 and PSA level at diagnosis. Overall survival was associated with PSA level, Gleason score and age. There was a linear increase in risk (overall survival) as PSA increased until 200 and no association thereafter. Models of overall survival and prostate cancer-specific mortality incorporating a risk stratification developed by Izumi et al. predicted overall survival but not prostate cancer-specific mortality. The use of this stratification did not improve model accuracy. Only a small number of men (4.2%) with prostate cancer present with PSA >100 ng/mL at diagnosis. Overall survival at five and ten years was significantly poorer in patients with PSA >100 ng/mL. In this cohort of men presenting with PSA >100 at diagnosis, PSA level was not associated with prostate cancer-specific mortality. Gleason score and metastases are significant prognostic factors in this group of men. © 2016 The Authors BJU International © 2016

  14. Experimental tests of the standard model

    International Nuclear Information System (INIS)

    Nodulman, L.

    1998-01-01

    The title implies an impossibly broad field, as the Standard Model includes the fermion matter states, as well as the forces and fields of SU(3) x SU(2) x U(1). For practical purposes, I will confine myself to electroweak unification, as discussed in the lectures of M. Herrero. Quarks and mixing were discussed in the lectures of R. Aleksan, and leptons and mixing were discussed in the lectures of K. Nakamura. I will essentially assume universality, that is flavor independence, rather than discussing tests of it. I will not pursue tests of QED beyond noting the consistency and precision of measurements of α EM in various processes including the Lamb shift, the anomalous magnetic moment (g-2) of the electron, and the quantum Hall effect. The fantastic precision and agreement of these predictions and measurements is something that convinces people that there may be something to this science enterprise. Also impressive is the success of the ''Universal Fermi Interaction'' description of beta decay processes, or in more modern parlance, weak charged current interactions. With one coupling constant G F , most precisely determined in muon decay, a huge number of nuclear instabilities are described. The slightly slow rate for neutron beta decay was one of the initial pieces of evidence for Cabbibo mixing, now generalized so that all charged current decays of any flavor are covered

  15. LUPUS I observations from the 2010 flight of the Balloon-borne large aperture submillimeter telescope for polarimetry

    International Nuclear Information System (INIS)

    Matthews, Tristan G.; Chapman, Nicholas L.; Novak, Giles; Ade, Peter A. R.; Hargrave, Peter C.; Nutter, David; Angilè, Francesco E.; Devlin, Mark J.; Klein, Jeffrey; Benton, Steven J.; Fissel, Laura M.; Gandilo, Natalie N.; Netterfield, Calvin B.; Chapin, Edward L.; Fukui, Yasuo; Gundersen, Joshua O.; Korotkov, Andrei L.; Moncelsi, Lorenzo; Mroczkowski, Tony K.; Olmi, Luca

    2014-01-01

    The Balloon-borne Large Aperture Submillimeter Telescope for Polarimetry (BLASTPol) was created by adding polarimetric capability to the BLAST experiment that was flown in 2003, 2005, and 2006. BLASTPol inherited BLAST's 1.8 m primary and its Herschel/SPIRE heritage focal plane that allows simultaneous observation at 250, 350, and 500 μm. We flew BLASTPol in 2010 and again in 2012. Both were long duration Antarctic flights. Here we present polarimetry of the nearby filamentary dark cloud Lupus I obtained during the 2010 flight. Despite limitations imposed by the effects of a damaged optical component, we were able to clearly detect submillimeter polarization on degree scales. We compare the resulting BLASTPol magnetic field map with a similar map made via optical polarimetry. (The optical data were published in 1998 by J. Rizzo and collaborators.) The two maps partially overlap and are reasonably consistent with one another. We compare these magnetic field maps to the orientations of filaments in Lupus I, and we find that the dominant filament in the cloud is approximately perpendicular to the large-scale field, while secondary filaments appear to run parallel to the magnetic fields in their vicinities. This is similar to what is observed in Serpens South via near-IR polarimetry, and consistent with what is seen in MHD simulations by F. Nakamura and Z. Li.

  16. Numerical relativity in spherical coordinates with the Einstein Toolkit

    Science.gov (United States)

    Mewes, Vassilios; Zlochower, Yosef; Campanelli, Manuela; Ruchlin, Ian; Etienne, Zachariah B.; Baumgarte, Thomas W.

    2018-04-01

    Numerical relativity codes that do not make assumptions on spatial symmetries most commonly adopt Cartesian coordinates. While these coordinates have many attractive features, spherical coordinates are much better suited to take advantage of approximate symmetries in a number of astrophysical objects, including single stars, black holes, and accretion disks. While the appearance of coordinate singularities often spoils numerical relativity simulations in spherical coordinates, especially in the absence of any symmetry assumptions, it has recently been demonstrated that these problems can be avoided if the coordinate singularities are handled analytically. This is possible with the help of a reference-metric version of the Baumgarte-Shapiro-Shibata-Nakamura formulation together with a proper rescaling of tensorial quantities. In this paper we report on an implementation of this formalism in the Einstein Toolkit. We adapt the Einstein Toolkit infrastructure, originally designed for Cartesian coordinates, to handle spherical coordinates, by providing appropriate boundary conditions at both inner and outer boundaries. We perform numerical simulations for a disturbed Kerr black hole, extract the gravitational wave signal, and demonstrate that the noise in these signals is orders of magnitude smaller when computed on spherical grids rather than Cartesian grids. With the public release of our new Einstein Toolkit thorns, our methods for numerical relativity in spherical coordinates will become available to the entire numerical relativity community.

  17. Comparison of false-negative rates and limits of detection following macrofoam-swab sampling of Bacillus anthracis surrogates via Rapid Viability PCR and plate culture.

    Science.gov (United States)

    Hutchison, J R; Piepel, G F; Amidan, B G; Hess, B M; Sydor, M A; Deatherage Kaiser, B L

    2018-05-01

    We evaluated the effects of Bacillus anthracis surrogates, low surface concentrations, surface materials and assay methods on false-negative rate (FNR) and limit of detection (LOD 95 ) for recovering Bacillus spores using a macrofoam-swab sampling procedure. Bacillus anthracis Sterne or Bacillus atrophaeus Nakamura spores were deposited over a range of low target concentrations (2-500 per coupon) onto glass, stainless steel, vinyl tile and plastic. Samples were assayed using a modified Rapid Viability-PCR (mRV-PCR) method and the traditional plate culture method to obtain FNR and LOD 95 results. Mean FNRs tended to be lower for mRV-PCR compared to culturing, and increased as spore concentration decreased for all surface materials. Surface material, but not B. anthracis surrogate, influenced FNRs with the mRV-PCR method. The mRV-PCR LOD 95 was lowest for glass and highest for vinyl tile. LOD 95 values overall were lower for mRV-PCR than for the culture method. This study adds to the limited data on FNR and LOD 95 for mRV-PCR and culturing methods with low concentrations of B. anthracis sampled from various surface materials by the CDC macrofoam-swab method. These are key inputs for planning characterization and clearance studies for low contamination levels of B. anthracis. © 2018 The Society for Applied Microbiology.

  18. LUPUS I observations from the 2010 flight of the Balloon-borne large aperture submillimeter telescope for polarimetry

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, Tristan G.; Chapman, Nicholas L.; Novak, Giles [Center for Interdisciplinary Exploration and Research in Astrophysics (CIERA) and Department of Physics and Astronomy, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208 (United States); Ade, Peter A. R.; Hargrave, Peter C.; Nutter, David [Cardiff University, School of Physics and Astronomy, Queens Buildings, The Parade, Cardiff, CF24 3AA (United Kingdom); Angilè, Francesco E.; Devlin, Mark J.; Klein, Jeffrey [Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, PA 19104 (United States); Benton, Steven J.; Fissel, Laura M.; Gandilo, Natalie N.; Netterfield, Calvin B. [Department of Astronomy and Astrophysics, University of Toronto, 50 St. George Street Toronto, ON M5S 3H4 (Canada); Chapin, Edward L. [XMM SOC, ESAC, Apartado 78, E-28691 Villanueva de la Cañada, Madrid (Spain); Fukui, Yasuo [Department of Physics, Nagoya University, Nagoya 464-8602 (Japan); Gundersen, Joshua O. [Department of Physics, University of Miami, 1320 Campo Sano Drive, Coral Gables, FL 33146 (United States); Korotkov, Andrei L. [Department of Physics, Brown University, 182 Hope Street, Providence, RI 02912 (United States); Moncelsi, Lorenzo; Mroczkowski, Tony K. [California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125 (United States); Olmi, Luca [University of Puerto Rico, Rio Piedras Campus, Physics Department, Box 23343, UPR station, San Juan (Puerto Rico); and others

    2014-04-01

    The Balloon-borne Large Aperture Submillimeter Telescope for Polarimetry (BLASTPol) was created by adding polarimetric capability to the BLAST experiment that was flown in 2003, 2005, and 2006. BLASTPol inherited BLAST's 1.8 m primary and its Herschel/SPIRE heritage focal plane that allows simultaneous observation at 250, 350, and 500 μm. We flew BLASTPol in 2010 and again in 2012. Both were long duration Antarctic flights. Here we present polarimetry of the nearby filamentary dark cloud Lupus I obtained during the 2010 flight. Despite limitations imposed by the effects of a damaged optical component, we were able to clearly detect submillimeter polarization on degree scales. We compare the resulting BLASTPol magnetic field map with a similar map made via optical polarimetry. (The optical data were published in 1998 by J. Rizzo and collaborators.) The two maps partially overlap and are reasonably consistent with one another. We compare these magnetic field maps to the orientations of filaments in Lupus I, and we find that the dominant filament in the cloud is approximately perpendicular to the large-scale field, while secondary filaments appear to run parallel to the magnetic fields in their vicinities. This is similar to what is observed in Serpens South via near-IR polarimetry, and consistent with what is seen in MHD simulations by F. Nakamura and Z. Li.

  19. Comparison of false-negative rates and limits of detection following macrofoam-swab sampling of Bacillus anthracis surrogates via Rapid Viability PCR and plate culture

    Energy Technology Data Exchange (ETDEWEB)

    Hutchison, J. R. [National Security Directorate, Pacific Northwest National Laboratory, Richland WA USA; Piepel, G. F. [National Security Directorate, Pacific Northwest National Laboratory, Richland WA USA; Amidan, B. G. [National Security Directorate, Pacific Northwest National Laboratory, Richland WA USA; Hess, B. M. [National Security Directorate, Pacific Northwest National Laboratory, Richland WA USA; Sydor, M. A. [National Security Directorate, Pacific Northwest National Laboratory, Richland WA USA; Deatherage Kaiser, B. L. [National Security Directorate, Pacific Northwest National Laboratory, Richland WA USA

    2018-03-13

    Aims: We evaluated the effects of Bacillus anthracis surrogates, low surface concentrations, surface materials, and assay methods on false-negative rate (FNR) and limit of detection (LOD95) for recovering Bacillus spores using a macrofoam-swab sampling procedure. Methods and Results: Bacillus anthracis Sterne or Bacillus atrophaeus Nakamura spores were deposited over a range of low target concentrations (2 – 500 coupon-1) onto glass, stainless steel, vinyl tile, and plastic. Samples were assayed using a modified Rapid Viability-PCR (mRV-PCR) method and the traditional plate culture method to obtain FNR and LOD95 results. Conclusions: Mean FNRs tended to be lower for mRV-PCR compared to culturing, and increased as spore concentration decreased for all surface materials. Surface material, but not B. anthracis surrogate, influenced FNRs with the mRV-PCR method. The mRV-PCR LOD95 was lowest for glass and highest for vinyl tile. LOD95 values overall were lower for mRV-PCR than for the culture method. Significance and Impact of Study: This study adds to the limited data on FNR and LOD95 for mRV-PCR and culturing methods with low concentrations of B. anthracis sampled from various surface materials by the CDC macrofoam-swab method. These are key inputs for planning characterization and clearance studies for low contamination levels of B. anthracis.

  20. Application of particle-mesh Ewald summation to ONIOM theory

    International Nuclear Information System (INIS)

    Kobayashi, Osamu; Nanbu, Shinkoh

    2015-01-01

    Highlights: • Particle-mesh Ewald sum is extended to ONIOM scheme. • Non-adiabatic MD simulation in solution is performed. • The behavior of excited (Z)-penta-2,4-dieniminium cation in methanol is simulated. • The difference between gas phase and solution is predicted. - Abstract: We extended a particle mesh Ewald (PME) summation method to the ONIOM (our Own N-layered Integrated molecular Orbitals and molecular Mechanics) scheme (PME-ONIOM) to validate the simulation in solution. This took the form of a nonadiabatic ab initio molecular dynamics (MD) simulation in which the Zhu-Nakamura trajectory surface hopping (ZN-TSH) method was performed for the photoisomerization of a (Z)-penta-2,4-dieniminium cation (protonated Schiff base, PSB3) electronically excited to the S 1 state in a methanol solution. We also calculated a nonadiabatic ab initio MD simulation with only minimum image convention (MI-ONIOM). The lifetime determined by PME-ONIOM-MD was 3.483 ps. The MI-ONIOM-MD lifetime of 0.4642 ps was much shorter than those of PME-ONIOM-MD and the experimentally determined excited state lifetime. The difference eminently illustrated the accurate treatment of the long-range solvation effect, which destines the electronically excited PSB3 for staying in S 1 at the pico-second or the femto-second time scale.

  1. Microtremor Study of Site Effect for Disaster Mitigation and Geotechnical Purpose

    Science.gov (United States)

    Aswad, Sabrianto; Altin Massinai, Muh.; Syamsuddin

    2018-03-01

    Makassar city have relatively lower earthquake vulnerability compared to other regions in Indonesia, however detailed mapping related to seismic wave amplification needs to be done in the interest of geotechnical, regional planning and disaster mitigation. It is generally known that the magnitude of the damage during the occurrence of earthquakes or tremor occur periodically is influenced by the dynamic characteristics of the building as a function of seismic wave amplification. The degree of seismic wave amplification depends on several factors, including the thickness of the sediment layer, the level of compaction and the geological age factor. The purpose of this research is to investigate seismic vulnerability in Makassar by using spectral comparison through microtremor measurement. There are several of the approaches that can be done and microtremor is the easiest and cheapest method to understand these dynamic characteristics without causing damage effects. Spectra comparison technique used was popular by Nakamura, which is comparison technique of horizontal component noise spectra and the vertical component in sediment areas (H/V spectra). Results from seismic vulnerability index (SVI) distribution maps show values ranging from 0, 14 - 158, 31. In general, the eastern part of the city of Makassar near from coastal areas is more vulnerable to damage especially earthquakes or periodic earth tremor with certain dominant frequency compared with the western part of Makassar City.

  2. Physical inactivity is associated with decreased growth differentiation factor 11 in chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Tanaka R

    2018-04-01

    Full Text Available Rie Tanaka,1 Hisatoshi Sugiura,1 Mitsuhiro Yamada,1 Tomohiro Ichikawa,1 Akira Koarai,1 Naoya Fujino,1 Satoru Yanagisawa,1 Katsuhiro Onodera,1 Tadahisa Numakura,1 Kei Sato,1 Yorihiko Kyogoku,1 Hirohito Sano,1 Shun Yamanaka,1 Tatsuma Okazaki,1 Tsutomu Tamada,1 Motohiko Miura,2 Tsuneyuki Takahashi,3 Masakazu Ichinose1 1Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Aoba-ku, Sendai, Japan; 2Department of Respiratory Medicine, Tohoku Rosai Hospital, Aoba-ku, Sendai, Japan; 3Department of Internal Medicine, Tohoku Medical and Pharmaceutical University Wakabayashi Hospital, Wakabayashi-ku, Sendai, Japan Background: Growth differentiation factor 11 (GDF11 is reported to possess anti-aging and rejuvenating effects, including muscle regeneration and to be highly expressed in skeletal muscle. Recently, we demonstrated that the levels of plasma GDF11 were decreased in COPD. However, the effect of decreased circulating GDF11 in the pathophysiology of COPD remains unknown. The aim of this study is to investigate the association between the plasma GDF11 levels and various clinical parameters in patients with COPD. Patients and methods: Eighteen ex-smokers as control subjects and 70 COPD patients participated in the current study. We measured the levels of plasma GDF11 using immunoblotting, lung function, physical activity using a triaxial accelerometer, quadriceps strength, exercise capacity, and systemic inflammatory markers. We investigated the association between the levels of plasma GDF11 and these clinical parameters. Results: The levels of plasma GDF11 in the COPD patients had significant positive correlations with the data of lung function. Furthermore, the levels of plasma GDF11 were significantly correlated with the physical activity, quadriceps strength, and exercise capacity. Moreover, the levels of plasma GDF11 were significantly correlated with the data of inflammatory markers. Although various factors were

  3. Tipepidine in children with attention deficit/hyperactivity disorder: a 4-week, open-label, preliminary study

    Directory of Open Access Journals (Sweden)

    Sasaki T

    2014-01-01

    Full Text Available Tsuyoshi Sasaki,1,2 Kenji Hashimoto,3 Masumi Tachibana,1 Tsutomu Kurata,1 Keiko Okawada,1 Maki Ishikawa,1 Hiroshi Kimura,2 Hideki Komatsu,2 Masatomo Ishikawa,2 Tadashi Hasegawa,2 Akihiro Shiina,1 Tasuku Hashimoto,2 Nobuhisa Kanahara,3 Tetsuya Shiraishi,2 Masaomi Iyo1–31Department of Child Psychiatry, Chiba University Hospital, 2Department of Psychiatry, Chiba University Graduate School of Medicine, 3Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, JapanBackground: Tipepidine (3-[di-2-thienylmethylene]-1-methylpiperidine has been used solely as a nonnarcotic antitussive in Japan since 1959. The safety of tipepidine in children and adults has already been established. It is reported that tipepidine inhibits G-protein-coupled inwardly rectifying potassium (GIRK-channel currents. The inhibition of GIRK channels by tipepidine is expected to modulate the level of monoamines in the brain. We put forward the hypothesis that tipepidine can improve attention deficit/hyperactivity disorder (ADHD symptoms by modulating monoaminergic neurotransmission through the inhibition of GIRK channels. The purpose of this open-label trial was to confirm whether treatment with tipepidine can improve symptoms in pediatric patients with ADHD.Subjects and methods: This was a 4-week, open-label, proof-of-efficacy pilot study for pediatric subjects with ADHD. Ten pediatric ADHD subjects (70% male; mean age, 9.9 years; combined [inattentive and hyperactive/impulsive] subtype, n=7; inattentive subtype, n=3; hyperimpulsive subtype, n=0 received tipepidine hibenzate taken orally at 30 mg/day for 4 weeks. All subjects were assessed using the ADHD Rating Scale IV (ADHD-RS, Japanese version, and the Das–Naglieri Cognitive Assessment System (DN-CAS, Japanese version.Results: A comparison of baseline scores and 4-week end-point scores showed that all the ADHD-RS scores (total scores, hyperimpulsive subscores, and inattentive subscores

  4. EDITORIAL: Invited papers from ISAMMA 2010 (Sendai, Japan, 12-16 July 2010) Invited papers from ISAMMA 2010 (Sendai, Japan, 12-16 July 2010)

    Science.gov (United States)

    Takahashi, M.; Saito, H.

    2011-02-01

    overseas. The programme involved 4 plenary talks, 37 invited talks, 85 contributed talks and 352 posters. All submitted papers were reviewed in order to meet the standards of Journal of Physics D: Applied Physics and Journal of Physics: Conference Series. We are grateful to all participants for their valuable contributions and active discussions. We gratefully acknowledge the financial support of 17 Japanese companies and 7 Japanese foundations. Invited papers from ISAMMA 2010 Contents Current status and recent topics of rare-earth permanent magnets S Sugimoto Alloying effect on the magnetic properties of RFeB-type bulk magnets H W Chang, C C Hsieh, J Y Gan, Y T Cheng, M F Shih and W C Chang Coercivity distributions in Nd-Fe-B sintered magnets produced by the grain boundary diffusion process H Nakamura, K Hirota, T Ohashi and T Minowa Recent progress in high Bs Fe-based nanocrystalline soft magnetic alloys M Ohta and Y Yoshizawa Electric-field effects on magnetic anisotropy in Pd/Fe/Pd(0 0 1) surface Shinya Haraguchi, Masahito Tsujikawa, Junpei Gotou and Tatsuki Oda Gate modulation of spin precession in a semiconductor channel Hyun Cheol Koo, Jae Hyun Kwon, Jonghwa Eom, Joonyeon Chang, Suk Hee Han and Mark Johnson Ferromagnetic resonance of epitaxial Fe nanodots grown on MgO measured using coplanar waveguides M Mizuguchi and K Takanashi Switching phase diagrams of current-induced magnetization switching in asymmetric MgO-based magnetic tunnel junctions Seung-Young Park, Jae-Ho Han, Se-Chung Oh, Jang-Eun Lee, Kyung-Tae Nam, Hyun-Woo Lee, Younghun Jo and Kyung-Jin Lee Temperature dependence of spin-dependent transport properties of Co2MnSi-based current-perpendicular-to-plane magnetoresistive devices Y Sakuraba, K Izumi, S Bosu, K Saito and K Takanashi Adsorbate-induced spin-polarization enhancement of Fe3O4(0 0 1) A Pratt, M Kurahashi, X Sun and Y Yamauchi Antiferromagnetic coupling between spinel ferrite and α-Fe layers in Fe3-δO4/MgO/Fe(0 0 1) epitaxial films Hideto

  5. The Interstellar Gas Dust Streams and Seeds of Life

    Science.gov (United States)

    Oleg, Khavroshkin; Vladislav, Tsyplakov

    Gas dust Streams from Double Stars & Lunar Seismicity. The time series of seismic events were generated as follows: on the ordinate axis the peak amplitudes of events in standard units, on abscissa axis - seismogram durations of the same moonquakes and subsequent time intervals between them were used. Spectrum of the series disclosed time picks on hidden cosmological periodicities of lunar seismicity. A part of results (picks) presents orbital periods of double stars nearest to the Solar system. The explanation of that results is existing gas-dust streams from binary stars systems and interacting of it with lunar surface. Information content of the Nakamura`s Catalog of moonquakes is very rich: from solar-earth tides to clustering among the meteoroid streams [1, 2]. The histograms from meteoroid impacts seismic data revealed the seismic wave responses of the Moon to solar oscillations and the action on the lunar surface by dust-gas plasma of meteoroid streams [3]. The time series of seismic events were generated as follows: on an axis of ordinates - the peak amplitudes of events in standard units, on an abscissa - seismogram durations of the same moonquakes and subsequent time intervals between them were put aside [4]. Spectrum of the series of meteoroid streams seismicity disclosed time picks on orbital periods some planets and their satellites and solar oscillations [4, 5]. The research of peculiarities of histogram envelopes [3] and comparative common analysis solar bursts data and mass meteoroid distribution are confirmed [3, 4] and revealed Forbush`s effect for gas-dust plasma [6]. Hidden astrophysical periodicities of lunar seismicity were obtained early from an analysis of time series [7] which were similarity to series [4]. The path of results of [7] is presented in the Table where picks presents orbital periods of double stars nearest to the Solar system. Hypothesis for explanation of the Table results is existing gas-dust streams from binary stars near

  6. JENIS, UKURAN DAN DAERAH PENANGKAPAN HIU THRESHER (FAMILI ALOPIIDAE YANG TERTANGKAP RAWAI TUNA DI SAMUDERA HINDIA

    Directory of Open Access Journals (Sweden)

    Agustinus Anung Widodo

    2016-03-01

    Full Text Available Sebagai anggota Indian Ocean Tuna Commision (IOTC Indonesia wajib mengadopsi isi Resolusi IOTC 10/12 yang mengatur pengelolaan sumberdaya ikan hiu thresher (famili Alopiidae. Secara spesifik Indonesia belum melaksanakan pengelolaan sumberdaya hiu thresher karena spesies tersebut belum mendapatkan perhatian serius. Tulisan ini bermaksud menyampaikan hasil penelitian tentang ikan hiu thresher (Famili Alopiidae yang tertangkap rawai tuna di Samudera Hindia berbasis di Cilacap. Data diperoleh dari kegiatan pengambilan contoh di pelabuhan tahun 2010, kegiatan observasi di atas kapal rawai tuna bulan Januari 2010 dan laporan statistik PPS Cilacap tahun 2006-2010. Hasil kajian menunjukkan bahwa: (a di perairan Indonesia ada dua spesies dari tiga spesies hiu thresher yang ada di dunia, yaitu hiu monyet atau pelagic thresher (Alopias pelagicus Nakamura 1935 dan hiu paitan atau bigeye thresher (A. superciliosus Lowe 1840. Satu spesies lainnya yang belum pernah ditemukan adalah thinfin thresher (A.vulpinus Bonnaterre1788.  Dilihat dari teknologi rawai tuna yang digunakan, daerah sebaran hiu thresher sama dengan tuna di Samudera Hindia, sehingga sulit untuk menghindari tidak tertangkapnya hiu thresher oleh rawai tuna. Jumlah dari jenis hiu monyet yang tertangkap rawai tuna di Samudera Hindia berkisar 0,1-0,6 % dan hiu paitan berkisar 0,1-1,3 % dari total tangkapan. Ukuran hiu thresher yang tertangkap rawai tuna umumnya ikan yang telah dewasa (berkisar 54-74% dan diduga telah mengalami pemijahan. Hampir semua bagian hiu thresher dimanfaatkan sebagai bahan pangan dan farmasi. Selain dipasarkan di dalam negeri, ikan hiu thresher juga diekspor terutama siripnya ke manca negara dan terbanyak ke China.   As a member of IOTC, Indonesia is obliged to implement all IOTC’s resolutions including resolution 10/12 on the conservation of thresher sharks (Family Alopiidae caught in association with fisheries in the IOTC area of competence. Indonsia has not

  7. The role of the dorsoanterior striatum in implicit motivation: The case of the need for power

    Directory of Open Access Journals (Sweden)

    Oliver C Schultheiss

    2013-04-01

    Full Text Available Implicit motives like the need for power (nPower scale affective responses to need-specific rewards or punishments and thereby influence activity in motivational-brain structures. In this paper, we review evidence specifically supporting a role of the striatum in nPower. Individual differences in nPower predict (a enhanced implicit learning accuracy, but not speed, on serial-response tasks that are reinforced by power-related incentives (e.g., winning or losing a contest; dominant or submissive emotional expressions in behavioral studies and (b activation of the anterior caudate in response to dominant emotional expressions in brain imaging research. We interpret these findings on the basis of Hikosaka, Nakamura, Sakai, and Nakahara's (2002; Current Opinion in Neurobiology, 12(2, 217-222 model of central mechanisms of motor skill learning. The model assigns a critical role to the dorsoanterior striatum in dopamine-driven learning of spatial stimulus sequences. Based on this model, we suggest that the dorsoanterior striatum is the locus of nPower-dependent reinforcement. However, given the centrality of this structure in a wide range of motivational pursuits, we also propose that activity in the dorsoanterior striatum may not only reflect individual differences in nPower, but also in other implicit motives, like the need for achievement or the need for affiliation, provided that the proper incentives for these motives are present during reinforcement learning. We discuss evidence in support of such a general role of the dorsoanterior striatum in implicit motivation.

  8. Simulation of warpage induced by non-isothermal crystallization of co-polypropylene during the SLS process

    Science.gov (United States)

    Amado, Antonio; Schmid, Manfred; Wegener, Konrad

    2015-05-01

    Polymer processing using Additive Manufacturing Technologies (AM) has experienced a remarkable growth during the last years. The application range has been expanding rapidly, particularly driven by the so-called consumer 3D printing sector. However, for applications demanding higher requirements in terms of thermo-mechanical properties and dimensional accuracy the long established AM technologies such as Selective Laser Sintering (SLS) do not depict a comparable development. The higher process complexity hinders the number of materials that can be currently processed and the interactions between the different physics involved have not been fully investigated. In case of thermoplastic materials the crystallization kinetics coupled to the shrinkage strain development strongly influences the stability of the process. Thus, the current investigation presents a transient Finite Element simulation of the warpage effect during the SLS process of a new developed polyolefin (co-polypropylene) coupling the thermal, mechanical and phase change equations that control the process. A thermal characterization of the material was performed by means of DSC, integrating the Nakamura model with the classical Hoffmann-Lauritzen theory. The viscoelastic behavior was measured using a plate-plate rheometer at different degrees of undercooling and a phase change-temperature superposition principle was implemented. Additionally, for validation porpoises the warpage development of the first sintered layers was captured employing an optical device. The simulation results depict a good agreement with experimental measurements of deformation, describing the high sensitivity of the geometrical accuracy of the sintered parts related to the processing conditions.

  9. Gravitational radiation from the radial infall of highly relativistic point particles into Kerr black holes

    International Nuclear Information System (INIS)

    Cardoso, Vitor; Lemos, Jose P.S.

    2003-01-01

    In this paper, we consider the gravitational radiation generated by the collision of highly relativistic particles with rotating Kerr black holes. We use the Sasaki-Nakamura formalism to compute the waveform, energy spectra, and total energy radiated during this process. We show that the gravitational spectrum for high-energy collisions has definite characteristic universal features, which are independent of the spin of the colliding objects. We also discuss the possible connections between these results and black-hole-black-hole collisions at the speed of light. Our results show that during the high-speed collision of a nonrotating hole with a rotating one, at most 35% of the total energy can get converted into gravitational waves. This 35% efficiency occurs only in the most optimistic situation, that of a zero impact parameter collision, along the equatorial plane, with an almost extreme Kerr black hole. In the general situation, the total gravitational energy radiated is expected to be much less, especially if the impact parameter increases. Thus, if one is able to produce black holes at the CERN Large Hadron Collider, at most 35% of the partons' energy should be emitted during the so-called balding phase. This energy will be missing, since we do not have gravitational wave detectors able to measure such amplitudes. The collision at the speed of light between one rotating black hole and a nonrotating one or two rotating black holes turns out to be the most efficient gravitational wave generator in the Universe

  10. Estimation of soft sediment thickness in Kuala Lumpur based on microtremor observation data

    Science.gov (United States)

    Chiew, Chang Chyau; Cheah, Yi Ben; Tan, Chin Guan; Lau, Tze Liang

    2017-10-01

    Seismic site effect is one of the major concerns in earthquake engineering. Soft ground tends to amplify the seismic wave in surficial geological layers. The determination of soft ground thickness on the surface layers of the earth is an important input for seismic hazard assessment. This paper presents an easy and convenient approach to estimate the soft sediment thickness at the site using microtremor observation technique. A total number of 133 survey points were conducted in selected sites around Kuala Lumpur area using a microtremor measuring instrument, but only 103 survey points contributed to the seismic microzonation and sediment thickness plots. The bedrock of Kuala Lumpur area is formed by Kenny Hill Formation, limestone, granite, and the Hawthornden Schist; however, the thickness of surface soft ground formed by alluvial deposits, mine tailings, and residual soils remains unknown. Hence, the predominant frequency of the ground in each site was determined based on Nakamura method. A total number of 14 sites with known depth to bedrock from the supply of geotechnical reports in the study area were determined. An empirical correlation was developed to relate the ground predominant frequency and soft ground thickness. This correlation may contribute to local soil underlying the subsurface of Kuala Lumpur area. The finding provides an important relationship for engineers to estimate the soft ground thickness in Kuala Lumpur area based on the dynamic characteristics of the ground measured from microtremor observation.

  11. Relationship between soft stratum thickness and predominant frequency of ground based on microtremor observation data

    Science.gov (United States)

    Chia, Kenny; Lau, Tze Liang

    2017-07-01

    Despite categorized as low seismicity group, until being affected by distant earthquake ground motion from Sumatra and the recent 2015 Sabah Earthquake, Malaysia has come to realize that seismic hazard in the country is real and has the potential to threaten the public safety and welfare. The major concern in this paper is to study the effect of local site condition, where it could amplify the magnitude of ground vibration at sites. The aim for this study is to correlate the thickness of soft stratum with the predominant frequency of soil. Single point microtremor measurements were carried out at 24 selected points where the site investigation reports are available. Predominant period and frequency at each site are determined by Nakamura's method. The predominant period varies from 0.22 s to 0.98 s. Generally, the predominant period increases when getting closer to the shoreline which has thicker sediments. As far as the thickness of the soft stratum could influence the amplification of seismic wave, the advancement of micotremor observation to predict the thickness of soft stratum (h) from predominant frequency (fr) is of the concern. Thus an empirical relationship h =54.917 fr-1.314 is developed based on the microtremor observation data. The empirical relationship will be benefited in the prediction of thickness of soft stratum based on microtremor observation for seismic design with minimal cost compared to conventional boring method.

  12. Numerical relativity for D dimensional axially symmetric space-times: Formalism and code tests

    International Nuclear Information System (INIS)

    Zilhao, Miguel; Herdeiro, Carlos; Witek, Helvi; Nerozzi, Andrea; Sperhake, Ulrich; Cardoso, Vitor; Gualtieri, Leonardo

    2010-01-01

    The numerical evolution of Einstein's field equations in a generic background has the potential to answer a variety of important questions in physics: from applications to the gauge-gravity duality, to modeling black hole production in TeV gravity scenarios, to analysis of the stability of exact solutions, and to tests of cosmic censorship. In order to investigate these questions, we extend numerical relativity to more general space-times than those investigated hitherto, by developing a framework to study the numerical evolution of D dimensional vacuum space-times with an SO(D-2) isometry group for D≥5, or SO(D-3) for D≥6. Performing a dimensional reduction on a (D-4) sphere, the D dimensional vacuum Einstein equations are rewritten as a 3+1 dimensional system with source terms, and presented in the Baumgarte, Shapiro, Shibata, and Nakamura formulation. This allows the use of existing 3+1 dimensional numerical codes with small adaptations. Brill-Lindquist initial data are constructed in D dimensions and a procedure to match them to our 3+1 dimensional evolution equations is given. We have implemented our framework by adapting the Lean code and perform a variety of simulations of nonspinning black hole space-times. Specifically, we present a modified moving puncture gauge, which facilitates long-term stable simulations in D=5. We further demonstrate the internal consistency of the code by studying convergence and comparing numerical versus analytic results in the case of geodesic slicing for D=5, 6.

  13. Annually resolved atmospheric radiocarbon records reconstructed from tree-rings

    Science.gov (United States)

    Wacker, Lukas; Bleicher, Niels; Büntgen, Ulf; Friedrich, Michael; Friedrich, Ronny; Diego Galván, Juan; Hajdas, Irka; Jull, Anthony John; Kromer, Bernd; Miyake, Fusa; Nievergelt, Daniel; Reinig, Frederick; Sookdeo, Adam; Synal, Hans-Arno; Tegel, Willy; Wesphal, Torsten

    2017-04-01

    The IntCal13 calibration curve is mainly based on data measured by decay counting with a resolution of 10 years. Thus high frequency changes like the 11-year solar cycles or cosmic ray events [1] are not visible, or at least not to their full extent. New accelerator mass spectrometry (AMS) systems today are capable of measuring at least as precisely as decay counters [2], with the advantage of using 1000 times less material. The low amount of material required enables more efficient sample preparation. Thus, an annually resolved re-measurement of the tree-ring based calibration curve can now be envisioned. We will demonstrate with several examples the multitude of benefits resulting from annually resolved radiocarbon records from tree-rings. They will not only allow for more precise radiocarbon dating but also contain valuable new astrophysical information. The examples shown will additionally indicate that it can be critical to compare AMS measurements with a calibration curve that is mainly based on decay counting. We often see small offsets between the two measurement techniques, while the reason is yet unknown. [1] Miyake F, Nagaya K, Masuda K, Nakamura T. 2012. A signature of cosmic-ray increase in AD 774-775 from tree rings in Japan. Nature 486(7402):240-2. [2] Wacker L, Bonani G, Friedrich M, Hajdas I, Kromer B, Nemec M, Ruff M, Suter M, Synal H-A, Vockenhuber C. 2010. MICADAS: Routine and high-precision radiocarbon dating. Radiocarbon 52(2):252-62.

  14. Tore-Supra infrared thermography system, a real steady-state diagnostic

    International Nuclear Information System (INIS)

    Guilhem, D.; Bondil, J.L.; Bertrand, B.; Desgranges, C.; Lipa, M.; Messina, P.; Missirlian, M.; Portafaix, C.; Reichle, R.; Roche, H.; Saille, A.

    2005-01-01

    Tore-Supra Tokamak (I p = 1.5 MA, B t = 4 T) has been constructed with a steady-state magnetic field using super-conducting magnets and water-cooled plasma facing components (PFCs) for high-performance long pulse plasma discharges. When not actively cooled, plasma facing components can only accumulate a limited amount of energy since the temperature increases continuously during the discharge until radiation cooling equals the incoming heat flux. Such an environment is found in the JET Tokamak [JET Team, IAEA-CN-60/A1-3, Seville, 1994] and on TRIAM [M. Sakamoto, H. Nakashima, S. Kawasaki, A. Iyomasa, S.V. Kulkarni, M. Hasegawa, E. Jotaki, H. Zushi, K. Nakamura, K. Hanada, S. Itoh, Static and dynamic properties of wall recycling in TRIAM-1M, J. Nucl. Mater. 313-316 (2003) 519-523] [Y. Kamada, et al., Nucl. Fusion 3 (1999) 1845]. In Tore-Supra, the surface temperature of the actively cooled plasma facing components reach steady state within a second. We present here the Tore-Supra thermographic system, made of seven endoscope bodies equipped so far with eight infrared (IR) cameras. It has to be noted that this diagnostic is the first diagnostic to be actively cooled, as required for steady state. The main purpose of such a diagnostic is to prevent the plasma to damage the actively cooled plasma facing components (ACPFCs), which consist of the toroidal pumped limiter (TPL), 7 m 2 , and of five radio-frequency antennae, 1.5 m 2 each

  15. Adding metoclopramide to paroxetine induced extrapyramidal symptoms and hyperprolactinemia in a depressed woman: a case report

    Directory of Open Access Journals (Sweden)

    Igata R

    2016-09-01

    Full Text Available Ryohei Igata, Hikaru Hori, Kiyokazu Atake, Asuka Katsuki, Jun Nakamura Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Japan Abstract: A 54-year-old Japanese woman was diagnosed with major depressive disorder and prescribed paroxetine 20 mg/day. In around May 2013, the patient experienced gastric discomfort, so metoclopramide was prescribed. Beginning on June 4, 2013, the patient was given metoclopramide, 10 mg intravenously, twice per week. On the seventh day after beginning metoclopramide, facial hot flushes, increased sweating, muscle rigidity, and galactorrhea were noted. Extrapyramidal symptoms (EPS rapidly subsided in response to an intramuscular injection of biperiden. Blood biochemical tests revealed an elevated serum prolactin level of 44 ng/mL. After stopping metoclopramide, EPS disappeared. Serum prolactin level decreased to 15 ng/mL after 4 weeks. In our case, although no adverse reactions had previously occurred following the administration of metoclopramide, the patient developed EPS and hyperprolactinemia following the administration of this antiemetic in combination with paroxetine. Paroxetine and metoclopramide are mainly metabolized by CYP2D6, and they are inhibitors for CYP2D6. We report a case with EPS and hyperprolactinemia whose plasma paroxetine and metoclopramide level rapidly increased after the addition of metoclopramide. Our experience warrants the issuing of a precaution that adverse reactions may arise following the coadministration of metoclopramide and paroxetine even at their respective standard dose levels. Keywords: metoclopramide, paroxetine, extrapyramidal symptoms, SSRI, hyperprolactinemia, depression

  16. Discrimination between biological interfaces and crystal-packing contacts

    Directory of Open Access Journals (Sweden)

    Yuko Tsuchiya

    2008-11-01

    Full Text Available Yuko Tsuchiya1, Haruki Nakamura2, Kengo Kinoshita1,31Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minatoku, Tokyo, 108-8639, Japan; 2Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; 3Bioinformatics Research and Development, JST, 4-1-8 Honcho, Kawaguchi, Saitama, 332-0012, JapanAbstract: A discrimination method between biologically relevant interfaces and artificial crystal-packing contacts in crystal structures was constructed. The method evaluates protein-protein interfaces in terms of complementarities for hydrophobicity, electrostatic potential and shape on the protein surfaces, and chooses the most probable biological interfaces among all possible contacts in the crystal. The method uses a discriminator named as “COMP”, which is a linear combination of the complementarities for the above three surface features and does not correlate with the contact area. The discrimination of homo-dimer interfaces from symmetry-related crystal-packing contacts based on the COMP value achieved the modest success rate. Subsequent detailed review of the discrimination results raised the success rate to about 88.8%. In addition, our discrimination method yielded some clues for understanding the interaction patterns in several examples in the PDB. Thus, the COMP discriminator can also be used as an indicator of the “biological-ness” of protein-protein interfaces.Keywords: protein-protein interaction, complementarity analysis, homo-dimer interface, crystal-packing contact, biological interfaces

  17. iPS-Cinderella Story in Cell Biology

    Directory of Open Access Journals (Sweden)

    Editorial

    2010-01-01

    pluripotency and thus paving the way for use of iPS in humansIn this issue of JSRM we have Dr.Yukio Nakamura writing about Disease specific iPS cells which could serve as tools for understanding the underlying mechanisms of diseases which are less understood so far or which could be used as study models for drug discovery for disease therapy. Adding another positive futuristic step to this is the paper by Kataoka et al., who have shown that the iPS cells could be grown in a three dimensional scaffold in which their earlier studies have shown feasibility of a 200 time passaging of mouse foteal epithelial stem cells and neural stem cells. The strengths of Nakamura et al and that of Kataoka et al combined virtually, we see a much brighter picture for the iPS cells which might be in future much cleaner, be grown in an undifferentiated manner and be stored for long; then instead of cord blood storage all I dream is whenever a child is born we may simply custom make iPS for that child and cryopreserve it; May the dreams come true!Dr. Sheikh Riazuddin’s article about lin-c-kit+ BM-derived stem cells repair Infarcted Heart and Dr.Pravin Potdar’s article about Mesenchymal Stem Cells from adipose tissue give some basic understandings of the possible clinical translations. Happy reading!

  18. Magnetic properties of frictional volcanic materials

    Science.gov (United States)

    Kendrick, Jackie E.; Lavallée, Yan; Biggin, Andrew; Ferk, Annika; Leonhardt, Roman

    2015-04-01

    magnetisation (ARM), as expected for a thermal origin, the remanence of volcanic pseudotachylyte has been found to be comparable to an isothermal remanent magnetisation (IRM). Thus, the pseudotachylyte has experienced a strong magnetic field that overwrote the previous thermoremanent magnetisation of the magma, such as the strong local electric current that occurs in faults (e.g. Ferré et al., 2005). Additionally, the pseudotachylyte seems more often to comprise of uniaxial non-interacting single-domain particles compared to pseudo-single in the host, and to have a single Curie temperature whereas the host more commonly exhibits multiple phases. Differences in rock-magnetic parameters between the pseudotachylyte and host are significant, but not as high as those observed in granites by Nakamura et al. (2002) or Ferré et al. (2005), probably because granitic host rocks do not already carry a strong and stable remanence as do these extrusive volcanic rocks. The application of rock-magnetic tests in volcanology will undoubtedly continue to be a "go-to" tool for identification of pseudotachylytes, which are increasingly being recognised to play an important role in dome-building eruptions. Refs: Ferré, E.C., Zechmeister, M.S., Geissman, J.W., MathanaSekaran, N. and Kocak, K., 2005. The origin of high magnetic remanence in fault pseudotachylites: Theoretical considerations and implication for coseismic electrical currents. Tectonophysics, 402(1-4): 125-139. Nakamura, N., Hirose, T. and Borradaile, G.J., 2002. Laboratory verification of submicron magnetite production in pseudotachylytes: relevance for paleointensity studies. . Earth and Planetary Science Letters, 201(1): 13-18.

  19. Graphene oxide scaffold accelerates cellular proliferative response and alveolar bone healing of tooth extraction socket

    Directory of Open Access Journals (Sweden)

    Nishida E

    2016-05-01

    Full Text Available Erika Nishida,1 Hirofumi Miyaji,1 Akihito Kato,1 Hiroko Takita,2 Toshihiko Iwanaga,3 Takehito Momose,1 Kosuke Ogawa,1 Shusuke Murakami,1 Tsutomu Sugaya,1 Masamitsu Kawanami11Department of Periodontology and Endodontology, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan; 2Support Section for Education and Research, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan; 3Laboratory of Histology and Cytology, Hokkaido University Graduate School of Medicine, Sapporo, JapanAbstract: Graphene oxide (GO consisting of a carbon monolayer has been widely investigated for tissue engineering platforms because of its unique properties. For this study, we fabricated a GO-applied scaffold and assessed the cellular and tissue behaviors in the scaffold. A preclinical test was conducted to ascertain whether the GO scaffold promoted bone induction in dog tooth extraction sockets. For this study, GO scaffolds were prepared by coating the surface of a collagen sponge scaffold with 0.1 and 1 µg/mL GO dispersion. Scaffolds were characterized using scanning electron microscopy (SEM, physical testing, cell seeding, and rat subcutaneous implant testing. Then a GO scaffold was implanted into a dog tooth extraction socket. Histological observations were made at 2 weeks postsurgery. SEM observations show that GO attached to the surface of collagen scaffold struts. The GO scaffold exhibited an interconnected structure resembling that of control subjects. GO application improved the physical strength, enzyme resistance, and adsorption of calcium and proteins. Cytocompatibility tests showed that GO application significantly increased osteoblastic MC3T3-E1 cell proliferation. In addition, an assessment of rat subcutaneous tissue response revealed that implantation of 1 µg/mL GO scaffold stimulated cellular ingrowth behavior, suggesting that the GO scaffold exhibited good biocompatibility. The tissue ingrowth area and DNA contents of 1

  20. Study of non-isothermal crystallization of Eu{sup 3+} doped Zn{sub 2}SiO{sub 4} powders through the application of various macrokinetic models

    Energy Technology Data Exchange (ETDEWEB)

    Janković, Bojan, E-mail: bojanjan@ffh.bg.ac.rs [Faculty of Physical Chemistry, Department of the Dynamics and Structure of Matter, University of Belgrade, Studentski trg 12-16, P.O. Box 137, 11001 Belgrade (Serbia); Marinović-Cincović, Milena; Dramićanin, Miroslav D. [Vinča Institute of Nuclear Sciences, University of Belgrade, Mike Petrovića Alasa 12-14, P.O. Box 552, 11001 Belgrade (Serbia)

    2014-02-25

    Highlights: • Europium (Eu{sup 3+}) doped zinc silicate powders. • Sol–gel method. • Stochastic geometric and semi-empirical models. • The interface controlled growth with an increasing nucleation rate. • The improved Nakamura’s model. -- Abstract: Various macrokinetic models (Avrami, Evans, Tobin, Malkin, Dietz, Nakamura, and modified first-order models) were applied to describe non-isothermal crystallization kinetics of Eu{sup 3+} doped zinc silicate powders prepared via the sol–gel method. Analysis of the experimental data was carried out using a direct-fitting method such that the experimental data were fitted directly to each macrokinetic model using a non-linear multivariable regression computation procedure. Comparison of kinetic parameters obtained from the non-linear computation approach to those obtained from the traditional analytical procedure suggested that applicability and reliability of the direct-fitting method were satisfactory. Judging from the quality of the fit, only Nakamura’s model properly describe the temperature dependence of the relative crystallinity, which resulted in the total rejection of the Tobin model in describing the crystallization. With detailed kinetic examination it was concluded that crystallization mechanism of α-willemite doped samples combusted in a microwave oven (MW) follows interface controlled growth with an increasing nucleation rate, attached with geometric process-rate function obeying the improved (corrected) Nakamura’s model. It was found that the presence of non integer Avrami exponent values may indicate that crystallization occurs by more than one reaction mechanism, including the occurrence of autocatalytic behavior of a given system.

  1. Determinacion de periodos fundamentales del suelo mediante vibraciones ambientales en el municipio de Humacao, Puerto Rico

    Science.gov (United States)

    Cintron Aponte, Rommel

    La tecnica de Nakamura ha sido utilizada a nivel mundial para determinar periodos fundamentales del suelo. La tecnica consiste en calcular y graficar cocientes espectrales H/V de vibraciones ambientales registradas sobre el suelo. Mediciones de vibraciones ambientales fueron tomadas en 151 lugares dentro del municipio de Humacao, localizado al este de Puerto Rico. Los datos se procesaron utilizando espectros de Fourier y espectros de potencia. La tecnica fue validada al compararla con los resultados de cocientes espectrales H/V de registros de sismos debiles y tambien con una modelacion numerica realizada con datos de un ensayo "downhole". Las graficas de los cocientes espectrales H/V fueron divididas en casos y grupos, los cuales dependen de la facilidad para identificar el periodo fundamental pico y amplitudes en frecuencias menores de 1 Hz, respectivamente. Los resultados obtenidos con ambos espectros fueron comparados y se concluye que los mismos se complementan para proveer resultados mas confiables. Se crearon mapas de periodos fundamentales, factores de amplitud, isoperiodos y clasificacion sismica de sitio. Los mapas de isoperiodos fueron realizados en las zonas mas pobladas sobre depositos de suelo. El mapa de periodos fundamentales del suelo mostro buena correlacion con la geologia local. El mapa de clasificacion sismica derivado de periodos de sitio fue comparado con el mapa de clasificacion sismica derivado de barrenos geotecnicos. El mapa de clasificacion obtenido de periodos puede sobreestimar un poco algunas clasificaciones del suelo. Sin embargo, este mapa puede proveer un estimado aproximado de la velocidad de onda de corte promedio del suelo hasta una profundidad de 100 pies (30 metros).

  2. Axisymmetric general relativistic hydrodynamics: Long-term evolution of neutron stars and stellar collapse to neutron stars and black holes

    International Nuclear Information System (INIS)

    Shibata, Masaru

    2003-01-01

    We report a new implementation for axisymmetric simulation in full general relativity. In this implementation, the Einstein equations are solved using the Nakamura-Shibata formulation with the so-called cartoon method to impose an axisymmetric boundary condition, and the general relativistic hydrodynamic equations are solved using a high-resolution shock-capturing scheme based on an approximate Riemann solver. As tests, we performed the following simulations: (i) long-term evolution of nonrotating and rapidly rotating neutron stars, (ii) long-term evolution of neutron stars of a high-amplitude damping oscillation accompanied with shock formation, (iii) collapse of unstable neutron stars to black holes, and (iv) stellar collapses to neutron stars. Tests (i)-(iii) were carried out with the Γ-law equation of state, and test (iv) with a more realistic parametric equation of state for high-density matter. We found that this new implementation works very well: It is possible to perform the simulations for stable neutron stars for more than 10 dynamical time scales, to capture strong shocks formed at stellar core collapses, and to accurately compute the mass of black holes formed after the collapse and subsequent accretion. In conclusion, this implementation is robust enough to apply to astrophysical problems such as stellar core collapse of massive stars to a neutron star, and black hole, phase transition of a neutron star to a high-density star, and accretion-induced collapse of a neutron star to a black hole. The result for the first simulation of stellar core collapse to a neutron star started from a realistic initial condition is also presented

  3. La pesquería de tiburones oceánicos-costeros en los litorales de Colima, Jalisco y Michoacán

    Directory of Open Access Journals (Sweden)

    Angélica Cruz

    2011-06-01

    Full Text Available La pesquería de tiburón es una de las más importantes en el Pacífico mexicano, en la actualidad no se cuentan con los datos de la composición específica de las capturas de las diferentes flotas. En el presente trabajo se describen aspectos biológicos-pesqueros de las especies de tiburón, capturadas por la flota palangrera de mediana altura del puerto de Manzanillo, en un periodo anual de abril 2006-abril 2007, los muestreos se realizaron mensualmente a bordo de estas embarcaciones. La composición de las capturas estuvo representada por nueve especies (n=1 962, de las cuales Carcharhinus falciformis (Bibron, 1839 (88.12% sostiene esta pesquería y en segundo lugar Prionace glauca (Linnaeus, 1758 (8.21%. Las especies poco frecuentes fueron Sphyrna zygaena (Linnaeus, 1758 con (1.78%, Alopias pelagicus (Nakamura, 1935 (0.82%, Carcharhinus longimanus (Poey, 1861 (0.45%, Alopias superciliosus (Lowe, 1839 (0.35%, Carcharhinus leucas (Valenciennes, 1839 (0.1%, Carcharhinus limbatus (Valenciennes, 1839 (0.1% é Isurus oxyrinchus (Rafinesque, 1810 (0.05%. La fecundidad estimada para C. falciformis fue de 3-7 crías/hembra con tallas de 30-45cm LT; 40.57+2.03cm LT y P. glauca con 5-52 crías/hembra, con tallas de 5-18.6cm LT; 11.61±0.21cm LT. Por lo tanto se asume que C. falciformis presenta un ciclo concurrente y P. glauca probablemente un ciclo bianual consecutivo.

  4. Nonadiabatic ab initio molecular dynamics of photoisomerization reaction between 1,3-cyclohexadiene and 1,3,5-cis-hexatriene

    International Nuclear Information System (INIS)

    Ohta, Ayumi; Kobayashi, Osamu; Danielache, Sebastian O.; Nanbu, Shinkoh

    2015-01-01

    Highlights: • The photoisomerization between cyclohexadiene and hexatriene was simulated. • Nonadiabatic ab initio MD simulations were employed to elucidate the mechanism. • Each excitations to S_1 and S_2 were simulated using full-dimensional model. • Specific molecular motions at CoIns and molecular vibrations on S_1 PES were found. • The one-sided product branching ratio was obtained at the photoexcitation to S_2. - Abstract: The photoisomerization process between 1,3-cyclohexadiene (CHD) and 1,3,5-cis-hexatriene (HT) has been studied by nonadiabatic ab initio molecular dynamics based on trajectory surface-hopping approach with a full-dimensional reaction model. The quantum chemical calculations were treated at MS-MR-CASPT2 level for 8 electrons in 8 orbitals with the cc-pVDZ basis set. The Zhu–Nakamura formula was employed to evaluate nonadiabatic transition probabilities. S_1 and S_2 states were included in the photoisomerization dynamics. Lifetimes and CHD:HT branching ratios were computationally estimated on the basis of statistical analysis of multiple executed trajectories. The analysis of trajectories suggested that the nonadiabatic transitions at the S_0/S_1 and S_1/S_2 conical intersections (CoIn) are correlated to the Kekulé-type vibration and the C3–C4–C5 bending motion, respectively. The one-sided branching ratio was obtained by excitations to the S_2 state; 70:30. The critical branching process was found to be dominated by the location of CoIn in potential energy hypersurface of the excited state.

  5. Recovery Efficiency, False Negative Rate, and Limit of Detection Performance of a Validated Macrofoam-Swab Sampling Method with Low Surface Concentrations of Two Bacillus anthracis Surrogates

    Energy Technology Data Exchange (ETDEWEB)

    Piepel, Gregory F. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hutchison, Janine R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kaiser, Brooke L. D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Amidan, Brett G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Sydor, Michael A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Barrett, Christopher A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-06-16

    The performance of a macrofoam-swab sampling method was evaluated using Bacillus anthracis Sterne (BAS) and Bacillus atrophaeus Nakamura (BG) spores applied at nine low target amounts (2-500 spores) to positive-control plates and test coupons (2 in × 2 in) of four surface materials (glass, stainless steel, vinyl tile, and plastic). Test results from cultured samples were used to evaluate the effects of surrogate, surface concentration, and surface material on recovery efficiency (RE), false negative rate (FNR), and limit of detection. For RE, surrogate and surface material had statistically significant effects, but concentration did not. Mean REs were the lowest for vinyl tile (50.8% with BAS, 40.2% with BG) and the highest for glass (92.8% with BAS, 71.4% with BG). FNR values ranged from 0 to 0.833 for BAS and 0 to 0.806 for BG, with values increasing as concentration decreased in the range tested (0.078 to 19.375 CFU/cm2, where CFU denotes ‘colony forming units’). Surface material also had a statistically significant effect. A FNR-concentration curve was fit for each combination of surrogate and surface material. For both surrogates, the FNR curves tended to be the lowest for glass and highest for vinyl title. The FNR curves for BG tended to be higher than for BAS at lower concentrations, especially for glass. Results using a modified Rapid Viability-Polymerase Chain Reaction (mRV-PCR) analysis method were also obtained. The mRV-PCR results and comparisons to the culture results are discussed in a separate report.

  6. Recovery Efficiency, False Negative Rate, and Limit of Detection Performance of a Validated Macrofoam-Swab Sampling Method with Low Surface Concentrations of Two Bacillus anthracis Surrogates

    Energy Technology Data Exchange (ETDEWEB)

    Piepel, Gregory F. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hutchison, Janine R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deatherage Kaiser, Brooke L [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Amidan, Brett G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Sydor, Michael A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Barrett, Christopher A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-03-31

    The performance of a macrofoam-swab sampling method was evaluated using Bacillus anthracis Sterne (BAS) and Bacillus atrophaeus Nakamura (BG) spores applied at nine low target amounts (2-500 spores) to positive-control plates and test coupons (2 in. × 2 in.) of four surface materials (glass, stainless steel, vinyl tile, and plastic). Test results from cultured samples were used to evaluate the effects of surrogate, surface concentration, and surface material on recovery efficiency (RE), false negative rate (FNR), and limit of detection. For RE, surrogate and surface material had statistically significant effects, but concentration did not. Mean REs were the lowest for vinyl tile (50.8% with BAS, 40.2% with BG) and the highest for glass (92.8% with BAS, 71.4% with BG). FNR values ranged from 0 to 0.833 for BAS and 0 to 0.806 for BG, with values increasing as concentration decreased in the range tested (0.078 to 19.375 CFU/cm2, where CFU denotes ‘colony forming units’). Surface material also had a statistically significant effect. A FNR-concentration curve was fit for each combination of surrogate and surface material. For both surrogates, the FNR curves tended to be the lowest for glass and highest for vinyl title. The FNR curves for BG tended to be higher than for BAS at lower concentrations, especially for glass. Results using a modified Rapid Viability-Polymerase Chain Reaction (mRV-PCR) analysis method were also obtained. The mRV-PCR results and comparisons to the culture results will be discussed in a subsequent report.

  7. Galectin-3 and N-acetylglucosamine promote myogenesis and improve skeletal muscle function in the mdx model of Duchenne muscular dystrophy.

    Science.gov (United States)

    Rancourt, Ann; Dufresne, Sébastien S; St-Pierre, Guillaume; Lévesque, Julie-Christine; Nakamura, Haruka; Kikuchi, Yodai; Satoh, Masahiko S; Frenette, Jérôme; Sato, Sachiko

    2018-06-12

    The muscle membrane, sarcolemma, must be firmly attached to the basal lamina. The failure of proper attachment results in muscle injury, which is the underlying cause of Duchenne muscular dystrophy (DMD), in which mutations in the dystrophin gene disrupts the firm adhesion. In patients with DMD, even moderate contraction causes damage, leading to progressive muscle degeneration. The damaged muscles are repaired through myogenesis. Consequently, myogenesis is highly active in patients with DMD, and the repeated activation of myogenesis leads to the exhaustion of the myogenic stem cells. Therefore, approaches to reducing the risk of the exhaustion are to develop a treatment that strengthens the interaction between the sarcolemma and the basal lamina and increases the efficiency of the myogenesis. Galectin-3 is an oligosaccharide-binding protein and is known to be involved in cell-cell interactions and cell-matrix interactions. Galectin-3 is expressed in myoblasts and skeletal muscle, although its function in muscle remains elusive. In this study, we found evidence that galectin-3 and the monosaccharide N-acetylglucosamine, which increases the synthesis of binding partners (oligosaccharides) of galectin-3, promote myogenesis in vitro. Moreover, in the mdx mouse model of DMD, treatment with N-acetylglucosamine increased muscle-force production. The results suggest that treatment with N-acetylglucosamine might mitigate the burden of DMD.-Rancourt, A., Dufresne, S. S., St-Pierre, G., Lévesque, J.-C., Nakamura, H., Kikuchi, Y., Satoh, M. S., Frenette, J., Sato, S. Galectin-3 and N-acetylglucosamine promote myogenesis and improve skeletal muscle function in the mdx model of Duchenne muscular dystrophy.

  8. Spatiotopic updating of visual feature information.

    Science.gov (United States)

    Zimmermann, Eckart; Weidner, Ralph; Fink, Gereon R

    2017-10-01

    Saccades shift the retina with high-speed motion. In order to compensate for the sudden displacement, the visuomotor system needs to combine saccade-related information and visual metrics. Many neurons in oculomotor but also in visual areas shift their receptive field shortly before the execution of a saccade (Duhamel, Colby, & Goldberg, 1992; Nakamura & Colby, 2002). These shifts supposedly enable the binding of information from before and after the saccade. It is a matter of current debate whether these shifts are merely location based (i.e., involve remapping of abstract spatial coordinates) or also comprise information about visual features. We have recently presented fMRI evidence for a feature-based remapping mechanism in visual areas V3, V4, and VO (Zimmermann, Weidner, Abdollahi, & Fink, 2016). In particular, we found fMRI adaptation in cortical regions representing a stimulus' retinotopic as well as its spatiotopic position. Here, we asked whether spatiotopic adaptation exists independently from retinotopic adaptation and which type of information is behaviorally more relevant after saccade execution. We first adapted at the saccade target location only and found a spatiotopic tilt aftereffect. Then, we simultaneously adapted both the fixation and the saccade target location but with opposite tilt orientations. As a result, adaptation from the fixation location was carried retinotopically to the saccade target position. The opposite tilt orientation at the retinotopic location altered the effects induced by spatiotopic adaptation. More precisely, it cancelled out spatiotopic adaptation at the saccade target location. We conclude that retinotopic and spatiotopic visual adaptation are independent effects.

  9. Predicting the Maximum Dynamic Strength in Bench Press: The High Precision of the Bar Velocity Approach.

    Science.gov (United States)

    Loturco, Irineu; Kobal, Ronaldo; Moraes, José E; Kitamura, Katia; Cal Abad, César C; Pereira, Lucas A; Nakamura, Fábio Y

    2017-04-01

    Loturco, I, Kobal, R, Moraes, JE, Kitamura, K, Cal Abad, CC, Pereira, LA, and Nakamura, FY. Predicting the maximum dynamic strength in bench press: the high precision of the bar velocity approach. J Strength Cond Res 31(4): 1127-1131, 2017-The aim of this study was to determine the force-velocity relationship and test the possibility of determining the 1 repetition maximum (1RM) in "free weight" and Smith machine bench presses. Thirty-six male top-level athletes from 3 different sports were submitted to a standardized 1RM bench press assessment (free weight or Smith machine, in randomized order), following standard procedures encompassing lifts performed at 40-100% of 1RM. The mean propulsive velocity (MPV) was measured in all attempts. A linear regression was performed to establish the relationships between bar velocities and 1RM percentages. The actual and predicted 1RM for each exercise were compared using a paired t-test. Although the Smith machine 1RM was higher (10% difference) than the free weight 1RM, in both cases the actual and predicted values did not differ. In addition, the linear relationship between MPV and percentage of 1RM (coefficient of determination ≥95%) allow determination of training intensity based on the bar velocity. The linear relationships between the MPVs and the relative percentages of 1RM throughout the entire range of loads enable coaches to use the MPV to accurately monitor their athletes on a daily basis and accurately determine their actual 1RM without the need to perform standard maximum dynamic strength assessments.

  10. Long-term survival after a favorable response to anti-EGFR antibody plus chemotherapy to treat bone marrow metastasis: a case report of KRAS-wildtype rectal cancer

    Directory of Open Access Journals (Sweden)

    Nakamura S

    2017-02-01

    Full Text Available Sho Nakamura, Tadahisa Fukui, Shuhei Suzuki, Hiroyuki Takeda, Kaname Watanabe, Takashi Yoshioka Department of Clinical Oncology, Yamagata University Faculty of Medicine, Yamagata, Japan Abstract: Bone marrow metastasis is a rare consequence of colorectal cancer that results in a poor prognosis; few reports describe a favorable response to doublet chemotherapy combined with targeted therapy, which is currently the standard treatment. We experienced a case where anti-epidermal growth factor receptor (EGFR antibody produced a marked anti-tumor response to bone marrow metastasis that led to long-term survival. A 51-year-old man was diagnosed with a primary KRAS-wildtype rectal cancer with multiple metastases, including the bone marrow. Disease control was achieved for 10.8 months following chemotherapy with a modified FOLFOX6 regimen combined with an anti-EGFR antibody. He died of cancer 22.7 and 16.6 months after disease onset and first-line chemotherapy, respectively. This case shows that early tumor shrinkage and deepness of response to the anti-EGFR antibody were observed even in a patient with bone marrow metastasis. Anti-EGFR antibody therapy should therefore be considered even when a patient’s medical condition appears to be poor owing to bone marrow metastasis. Moreover, tumors that are likely to be sensitive to chemotherapy, such as RAS-wildtype colorectal cancers, can be considered for anti-EGFR antibody therapy even if the patient is considered unfit for chemotherapy. Keywords: colorectal cancer, anti-epidermal growth factor receptor antibody, molecular targeted therapies, disseminated intravascular coagulation, standard of care

  11. Association of microsatellite polymorphisms of the GPDS1 locus with normal tension glaucoma in the Japanese population

    Directory of Open Access Journals (Sweden)

    Kayo Nakamura

    2009-04-01

    Full Text Available Kayo Nakamura1*, Masao Ota2*, Akira Meguro1, et al1Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan; 2Departmentof Legal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, JapanBackground: To investigate whether the GPDS1 locus, a potential causative locus of pigment-dispersion syndrome, is associated with normal-tension glaucoma (NTG in Japanese patients. Materials and methods: We used polymerase chain reaction amplification with sequencespecific primers to analyze 20 polymorphic microsatellite markers in and around the GPDS1 locus with an automated DNA analyzer and automated fragment detection by fluorescent-based technology. The DNA samples used for these analyses were obtained from ethnicity- and gendermatched patients, including 141 Japanese patients with NTG and 101 healthy controls. Patients exhibiting a comparatively early onset were selected as this suggests that genetic factors may show stronger involvement.Results: One allele of D7S2462 exhibited a frequency that was significantly decreased in NTG cases compared to controls (P = 0.0013, Pc = 0.019, OR = 0.48, 95% CI = 0.30–0.75. Alleles at another six microsatellite loci were positively or negatively associated with NTG, but these associations did not retain statistical significance after Bonferroni correction (P < 0.05, Pc > 0.05.Conclusion: Our study showed a significant association between the GPDS1 locus and NTG, suggesting that there may be some genetic risk factor(s in the development of NTG.Keywords: microsatellite, normal tension glaucoma, glaucoma-related pigment dispersion syndrome, GPDS1, DPP6

  12. E-MSD: improving data deposition and structure quality.

    Science.gov (United States)

    Tagari, M; Tate, J; Swaminathan, G J; Newman, R; Naim, A; Vranken, W; Kapopoulou, A; Hussain, A; Fillon, J; Henrick, K; Velankar, S

    2006-01-01

    The Macromolecular Structure Database (MSD) (http://www.ebi.ac.uk/msd/) [H. Boutselakis, D. Dimitropoulos, J. Fillon, A. Golovin, K. Henrick, A. Hussain, J. Ionides, M. John, P. A. Keller, E. Krissinel et al. (2003) E-MSD: the European Bioinformatics Institute Macromolecular Structure Database. Nucleic Acids Res., 31, 458-462.] group is one of the three partners in the worldwide Protein DataBank (wwPDB), the consortium entrusted with the collation, maintenance and distribution of the global repository of macromolecular structure data [H. Berman, K. Henrick and H. Nakamura (2003) Announcing the worldwide Protein Data Bank. Nature Struct. Biol., 10, 980.]. Since its inception, the MSD group has worked with partners around the world to improve the quality of PDB data, through a clean up programme that addresses inconsistencies and inaccuracies in the legacy archive. The improvements in data quality in the legacy archive have been achieved largely through the creation of a unified data archive, in the form of a relational database that stores all of the data in the wwPDB. The three partners are working towards improving the tools and methods for the deposition of new data by the community at large. The implementation of the MSD database, together with the parallel development of improved tools and methodologies for data harvesting, validation and archival, has lead to significant improvements in the quality of data that enters the archive. Through this and related projects in the NMR and EM realms the MSD continues to improve the quality of publicly available structural data.

  13. Experiments on Ion-Ion Plasmas From Discharges

    Science.gov (United States)

    Leonhardt, Darrin; Walton, Scott; Blackwell, David; Murphy, Donald; Fernsler, Richard; Meger, Robert

    2001-10-01

    Use of both positive and negative ions in plasma processing of materials has been shown to be advantageous[1] in terms of better feature evolution and control. In this presentation, experimental results are given to complement recent theoretical work[2] at NRL on the formation and decay of pulsed ion-ion plasmas in electron beam generated discharges. Temporally resolved Langmuir probe and mass spectrometry are used to investigate electron beam generated discharges during the beam on (active) and off (afterglow) phases in a variety of gas mixtures. Because electron-beam generated discharges inherently[3] have low electron temperatures (<0.5eV in molecular gases), negative ion characteristics are seen in the active as well as afterglow phases since electron detachment increases with low electron temperatures. Analysis of temporally resolved plasma characteristics deduced from these measurements will be presented for pure O_2, N2 and Ar and their mixtures with SF_6. Oxygen discharges show no noticeable negative ion contribution during the active or afterglow phase, presumably due to the higher energy electron attachment threshold, which is well above any electron temperature. In contrast, SF6 discharges demonstrate ion-ion plasma characteristics in the active glow and are completely ion-ion in the afterglow. Comparison between these discharges with published cross sections and production mechanisms will also be presented. [1] T.H. Ahn, K. Nakamura & H. Sugai, Plasma Sources Sci. Technol., 5, 139 (1996); T. Shibyama, H. Shindo & Y. Horiike, Plasma Sources Sci. Technol., 5, 254 (1996). [2] See presentation by R. F. Fernsler, at this conference. [3] D. Leonhardt, et al., 53rd Annual GEC, Houston, TX.

  14. Slow-roll corrections in multi-field inflation: a separate universes approach

    Science.gov (United States)

    Karčiauskas, Mindaugas; Kohri, Kazunori; Mori, Taro; White, Jonathan

    2018-05-01

    In view of cosmological parameters being measured to ever higher precision, theoretical predictions must also be computed to an equally high level of precision. In this work we investigate the impact on such predictions of relaxing some of the simplifying assumptions often used in these computations. In particular, we investigate the importance of slow-roll corrections in the computation of multi-field inflation observables, such as the amplitude of the scalar spectrum Pζ, its spectral tilt ns, the tensor-to-scalar ratio r and the non-Gaussianity parameter fNL. To this end we use the separate universes approach and δ N formalism, which allows us to consider slow-roll corrections to the non-Gaussianity of the primordial curvature perturbation as well as corrections to its two-point statistics. In the context of the δ N expansion, we divide slow-roll corrections into two categories: those associated with calculating the correlation functions of the field perturbations on the initial flat hypersurface and those associated with determining the derivatives of the e-folding number with respect to the field values on the initial flat hypersurface. Using the results of Nakamura & Stewart '96, corrections of the first kind can be written in a compact form. Corrections of the second kind arise from using different levels of slow-roll approximation in solving for the super-horizon evolution, which in turn corresponds to using different levels of slow-roll approximation in the background equations of motion. We consider four different levels of approximation and apply the results to a few example models. The various approximations are also compared to exact numerical solutions.

  15. Neural correlates of auditory recognition memory in the primate dorsal temporal pole

    Science.gov (United States)

    Ng, Chi-Wing; Plakke, Bethany

    2013-01-01

    Temporal pole (TP) cortex is associated with higher-order sensory perception and/or recognition memory, as human patients with damage in this region show impaired performance during some tasks requiring recognition memory (Olson et al. 2007). The underlying mechanisms of TP processing are largely based on examination of the visual nervous system in humans and monkeys, while little is known about neuronal activity patterns in the auditory portion of this region, dorsal TP (dTP; Poremba et al. 2003). The present study examines single-unit activity of dTP in rhesus monkeys performing a delayed matching-to-sample task utilizing auditory stimuli, wherein two sounds are determined to be the same or different. Neurons of dTP encode several task-relevant events during the delayed matching-to-sample task, and encoding of auditory cues in this region is associated with accurate recognition performance. Population activity in dTP shows a match suppression mechanism to identical, repeated sound stimuli similar to that observed in the visual object identification pathway located ventral to dTP (Desimone 1996; Nakamura and Kubota 1996). However, in contrast to sustained visual delay-related activity in nearby analogous regions, auditory delay-related activity in dTP is transient and limited. Neurons in dTP respond selectively to different sound stimuli and often change their sound response preferences between experimental contexts. Current findings suggest a significant role for dTP in auditory recognition memory similar in many respects to the visual nervous system, while delay memory firing patterns are not prominent, which may relate to monkeys' shorter forgetting thresholds for auditory vs. visual objects. PMID:24198324

  16. Restoration of Apollo Data by the NSSDC and the PDS Lunar Data Node

    Science.gov (United States)

    Williams, David R.; Hills, H. Kent; Lowman, Paul D.; Taylor, Patrick T.; Guinness, Edward A.

    2011-01-01

    The Lunar Data Node (LDN), under the auspices of the Geosciences Node of the Planetary Data System (PDS), is restoring Apollo data archived at the National Space Science Data Center. The Apollo data were arch ived on older media (7 -track tapes. microfilm, microfiche) and in ob solete digital formats, which limits use of the data. The LDN is maki ng these data accessible by restoring them to standard formats and archiving them through PDS. The restoration involves reading the older m edia, collecting supporting data (metadata), deciphering and understa nding the data, and organizing into a data set. The data undergo a pe er review before archive at PDS. We will give an update on last year' s work. We have scanned notebooks from Otto Berg, P.1. for the Lunar Ejecta and Meteorites Experiment. These notebooks contain information on the data and calibration coefficients which we hope to be able to use to restore the raw data into a usable archive. We have scanned Ap ollo 14 and 15 Dust Detector data from microfilm and are in the proce ss of archiving thc scans with PDS. We are also restoring raw dust de tector data from magnetic tape supplied by Yosio Nakamura (UT Austin) . Seiichi Nagihara (Texas Tech Univ.) and others in cooperation with NSSDC are recovering ARCSAV tapes (tapes containing raw data streams from all the ALSEP instruments). We will be preparing these data for archive with PDS. We are also in the process of recovering and archivi ng data not previously archived, from the Apollo 16 Gamma Ray Spectro meter and the Apollo 17 Infrared Spectrometer.

  17. Control-matched comparison of refractive and visual outcomes between small incision lenticule extraction and femtosecond laser-assisted LASIK

    Directory of Open Access Journals (Sweden)

    Kataoka T

    2018-05-01

    Full Text Available Takahiro Kataoka,1 Tomoya Nishida,1 Azusa Murata,1 Mayuka Ito,1 Naoki Isogai,1 Rie Horai,1 Takashi Kojima,1,2 Yoko Yoshida,1 Tomoaki Nakamura1 1Nagoya Eye Clinic, Nagoya, Japan; 2Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan Purpose: This retrospective case-matched study aimed to compare visual and refractive outcomes between small incision lenticule extraction (SMILE and LASIK. Patients and methods: Patients who underwent SMILE (34 eyes of 23 patients or LASIK (34 eyes of 24 patients were enrolled and matched according to preoperative manifest refractive spherical equivalents. The mean preoperative manifest refractive spherical equivalent was −4.69±0.6 and −4.67±0.64 D in the SMILE and LASIK groups, respectively. The safety, efficacy, and predictability were compared 3 months after surgery. Changes in corneal refractive power from the center to peripheral points and their maintenance ratios were analyzed and compared between the two groups. Results: In the SMILE and LASIK groups, 82.4% and 85.3% of patients, respectively, achieved 20/13 or better uncorrected distance visual acuity (p=1.00. There were no eyes that lost two or more lines of corrected distance visual acuity in either group. The maintenance ratios of corneal refractive power changes at the peripheral points in the SMILE group were significantly higher than those in the LASIK group (p<0.05. Conclusion: Both groups achieved similar high efficacy and safety. SMILE surgery resulted in higher refractive power correction in the peripheral cornea than LASIK surgery. Keywords: small incision lenticule extraction, LASIK, corneal refractive power, refractive power correction efficiency, corneal topography

  18. Neural correlates of auditory recognition memory in the primate dorsal temporal pole.

    Science.gov (United States)

    Ng, Chi-Wing; Plakke, Bethany; Poremba, Amy

    2014-02-01

    Temporal pole (TP) cortex is associated with higher-order sensory perception and/or recognition memory, as human patients with damage in this region show impaired performance during some tasks requiring recognition memory (Olson et al. 2007). The underlying mechanisms of TP processing are largely based on examination of the visual nervous system in humans and monkeys, while little is known about neuronal activity patterns in the auditory portion of this region, dorsal TP (dTP; Poremba et al. 2003). The present study examines single-unit activity of dTP in rhesus monkeys performing a delayed matching-to-sample task utilizing auditory stimuli, wherein two sounds are determined to be the same or different. Neurons of dTP encode several task-relevant events during the delayed matching-to-sample task, and encoding of auditory cues in this region is associated with accurate recognition performance. Population activity in dTP shows a match suppression mechanism to identical, repeated sound stimuli similar to that observed in the visual object identification pathway located ventral to dTP (Desimone 1996; Nakamura and Kubota 1996). However, in contrast to sustained visual delay-related activity in nearby analogous regions, auditory delay-related activity in dTP is transient and limited. Neurons in dTP respond selectively to different sound stimuli and often change their sound response preferences between experimental contexts. Current findings suggest a significant role for dTP in auditory recognition memory similar in many respects to the visual nervous system, while delay memory firing patterns are not prominent, which may relate to monkeys' shorter forgetting thresholds for auditory vs. visual objects.

  19. Gefarnate stimulates mucin-like glycoprotein secretion in conjunctival tissue and ameliorates corneal epithelial damage in animal dry-eye models

    Directory of Open Access Journals (Sweden)

    Dota A

    2013-01-01

    Full Text Available Atsuyoshi Dota, Yuko Takaoka-Shichijo, Masatsugu NakamuraOphthalmic Research and Development Center, Santen Pharmaceutical Co, Ltd, Ikoma-shi, Nara, JapanPurpose: The aim of this study was to evaluate the effect of gefarnate on mucin-like glycoprotein secretion in isolated rabbit conjunctival tissue, and on corneal epithelial damage in rabbit and cat dry-eye models.Methods: Conjunctival tissue isolated from rabbits was treated with gefarnate. Mucin-like glycoprotein was detected in the culture supernatant by an enzyme-linked lectin assay. Gefarnate ointment was topically applied to eyes once daily for 7 days in the rabbit dry-eye model, in which the lacrimal glands, Harderian gland, and nictitating membrane were removed, or for 4 weeks in the cat dry-eye model, in which the lacrimal gland and nictitating membrane were removed. Corneal epithelial damage was evaluated by measurement of corneal permeability by rose bengal in the rabbit model or by fluorescein staining in the cat model.Results: Gefarnate stimulated mucin-like glycoprotein secretion in conjunctival tissue in a dose-dependent manner. In the rabbit dry-eye model, application of gefarnate ointment to the eyes resulted in a dose-dependent decrease in rose bengal permeability in the cornea, with the effect being significant at concentrations of ≥0.3%. In the cat dry-eye model, application of gefarnate ointment resulted in a significant decrease in the corneal fluorescein staining score.Conclusion: These results suggest that gefarnate stimulates in vitro secretion of mucin-like glycoprotein in conjunctival tissue and ameliorates corneal epithelial damage in animal dry-eye models. Gefarnate may therefore be effective for treating dry eye.Keywords: gefarnate, fluorescein staining, rose bengal permeability, rabbit, cat, dry eye

  20. Antimicrobial photodynamic activity and cytocompatibility of Au25(Capt18 clusters photoexcited by blue LED light irradiation

    Directory of Open Access Journals (Sweden)

    Miyata S

    2017-04-01

    Full Text Available Saori Miyata,1 Hirofumi Miyaji,1 Hideya Kawasaki,2 Masaki Yamamoto,2 Erika Nishida,1 Hiroko Takita,3 Tsukasa Akasaka,4 Natsumi Ushijima,3 Toshihiko Iwanaga,5 Tsutomu Sugaya1 1Department of Periodontology and Endodontology, Hokkaido University Graduate School of Dental Medicine, Kita-ku, Sapporo, 2Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita-shi, Osaka, 3Support Section for Education and Research, Hokkaido University Graduate School of Dental Medicine, 4Department of Biomedical, Dental Materials and Engineering, Graduate School of Dental Medicine, Hokkaido University, 5Department of Anatomy, Laboratory of Histology and Cytology, Hokkaido University Graduate School of Medicine, Kita-ku, Sapporo, Japan Abstract: Antimicrobial photodynamic therapy (aPDT has beneficial effects in dental treatment. We applied captopril-protected gold (Au25(Capt18 clusters as a novel photosensitizer for aPDT. Photoexcited Au clusters under light irradiation generated singlet oxygen (1O2. Accordingly, the antimicrobial and cytotoxic effects of Au25(Capt18 clusters under dental blue light-emitting diode (LED irradiation were evaluated. 1O2 generation of Au25(Capt18 clusters under blue LED irradiation (420–460 nm was detected by a methotrexate (MTX probe. The antimicrobial effects of photoexcited Au clusters (0, 5, 50, and 500 µg/mL on oral bacterial cells, such as Streptococcus mutans, Aggregatibacter actinomycetemcomitans, and Porphyromonas gingivalis, were assessed by morphological observations and bacterial growth experiments. Cytotoxicity testing of Au clusters and blue LED irradiation was then performed against NIH3T3 and MC3T3-E1 cells. In addition, the biological performance of Au clusters (500 µg/mL was compared to an organic dye photosensitizer, methylene blue (MB; 10 and 100 µg/mL. We confirmed the 1O2 generation ability of Au25(Capt18 clusters through the fluorescence

  1. The effects of a life goal-setting technique in a preventive care program for frail community-dwelling older people: a cluster nonrandomized controlled trial.

    Science.gov (United States)

    Yuri, Yoshimi; Takabatake, Shinichi; Nishikawa, Tomoko; Oka, Mari; Fujiwara, Taro

    2016-05-12

    Frailty among older people is associated with an increased risk of needing care. There have been many reports on preventive care programs for frail older people, but few have shown positive effects on disability prevention. Physical exercise programs for frail older people affect elements such as physical fitness and balance, but are less effective for disability outcomes and are not followed up in the longer term. We developed a life goal-setting technique (LGST). Our objective was to determine the effect of a LGST plus standard preventive care program for community-dwelling frail older people. We used a cluster nonrandomized controlled trial with seven intervention and nine matched control groups, with baseline assessment and follow-up at 3, 6, and 9 months. Participants were 176 frail older people, aged 65 years or over, living in the community in Izumi, Osaka, Japan. All participants attended regular 120 min preventive care exercise classes each week, over 3 months. They also received oral care and nutrition education. The intervention groups alone received life goal-setting support. We assessed outcomes longitudinally, comparing pre-intervention with follow-up. The primary outcome measure was health improvement according to the Japanese Ministry of Health, Labour and Welfare's "Kihon Checklist" for assessment of frailty and quality of life (QOL), analyzed with a two-way ANOVA and post-test comparison. Secondary outcomes included physical functions and assessment of life goals. The improvement on the Kihon Checklist for the intervention group was approximately 60 % from baseline to 9-months follow-up; the control group improved by approximately 40 %. The difference between groups was significant at 3-month (p = 0.043) and 6-month (p = 0.015) follow-ups but not at 9-month (p = 0.098) follow-up. Analysis of QOL yielded a significant time × group interaction effect (p = 0.022). The effect was significant at 3 months in the intervention

  2. PREFACE: Nanospintronics design and realization

    Science.gov (United States)

    Akai, Hisazumi; Katayama-Yoshida, Hiroshi; Kasai, Hideaki

    2004-12-01

    oral presentations and 44 contributed posters. The conference also has additional financial support from the Asahi Glass Foundation, the Foundation for Promotion of Material Science and Technology of Japan, the Izumi Science and Technology Foundation, the Kansai Research Foundation for Technology Promotion, the Kao Foundation for Arts and Sciences, the Murata Science Foundation, the Nanotechnology Researchers Network Center of Japan, and the Nippon Sheet Glass Foundation for Materials Science and Engineering. The 2nd International Conference on Nanospintronics Design and Realization will be held in Germany, in 2007, and will be organized by Stefan Blügel, Patrick Bruno, and Dieter Weiss. We hope to see you there.

  3. PREFACE Preface

    Science.gov (United States)

    Takahashi, Migaku; Saito, Hitoshi; Yoshimura, Satoru; Takanashi, Koki; Sahashi, Masashi; Tsunoda, Masakiyo

    2011-01-01

    23 countries, with about 40 percent of participants attending from overseas (see figure). The program involved 4 plenary talks (45 minutes each), 37 invited talks (30 minutes), 85 contributed talks (15 minutes), and 352 posters. Pie chart Organizing Committee of ISAMMA 2010 M TakahashiTohoku Univ., Japan, Chairman K TakanashiTohoku Univ., Japan, Chair of the Program Committee H SaitoAkita Univ., Japan, Chair of the Publication Committee M SahashiTohoku Univ., Japan, Chair of the Treasury Committee M TsunodaTohoku Univ., Japan, General Secretary H AkinagaAIST, Japan H FukunagaNagasaki Univ., Japan K HonoNIMS, Japan S IshioAkita Univ., Japan S IwataNagoya Univ., Japan K NakagawaNihon Univ., Japan S NakagawaTokyo Inst. of Tech., Japan T OnoKyoto Univ., Japan Y SuzukiOsaka Univ., Japan M TanakaEhime Univ., Japan T Tanaka Univ. of Tokyo, Japan Program Committee of ISAMMA 2010 K TakanashiTohoku Univ., Japan, ChairS MizukamiTohoku Univ., Japan M MizuguchiTohoku Univ., Japan, Vice-chairH NaganumaTohoku Univ., Japan M DoiTohoku Univ., JapanS NakagawaTokyo Inst. of Tech., Japan A FujitaTohoku Univ., JapanK NakamuraTohoku Univ., Japan K IshiyamaTohoku Univ., JapanK OnoKEK, Japan T KatoNagoya Univ., JapanT OnoKyoto Univ., Japan T KawagoeOsaka Pref. Univ.of Edu., JapanF SatoTohoku Univ., Japan O KitakamiTohoku Univ., JapanM ShiraiTohoku Univ., Japan Y KitamotoTokyo Inst. of Tech., JapanS SugimotoTohoku Univ., Japan F MatsukuraTohoku Univ., JapanM YamaguchiTohoku Univ., Japan C MitsumataHitachi Metals, Japan Publication Committee of ISAMMA 2010 H SaitoAkita Univ., Japan, ChairS MitaniNIMS, Japan S YoshimuraAkita Univ., Japan, Vice-chairH MuraokaTohoku, Japan Y AndoTohoku Univ., JapanM NakanoNagasaki Univ., Japan J AriakeAIT, JapanR NakataniOsaka Univ., Japan H AsanoNagoya Univ., JapanK O'GradyUniv. of York, UK M FutamotoChuo Univ., JapanA SakumaTohoku Univ., Japan J HayakawaHitachi, ARL, JapanT SatoKeio Univ., Japan T HondaKyushu Inst. of Tech., JapanT SatoShinshu Univ., Japan M

  4. Excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability

    Directory of Open Access Journals (Sweden)

    Abrouk M

    2016-12-01

    Full Text Available Michael Abrouk,1 Ethan Levin,2 Merrick Brodsky,1 Jessica R Gandy,1 Mio Nakamura,2 Tian Hao Zhu,3 Benjamin Farahnik,4 John Koo,2 Tina Bhutani2 1Irvine School of Medicine, Irvine, 2Department of Dermatology, Psoriasis and Skin Treatment Center, University of California, San Francisco, 3Department of Dermatology, University of Southern California Keck School of Medicine, Los Angeles, CA, 4Department of Dermatology, University of Vermont College of Medicine, Burlington, VT, USA Introduction: The 308 nm excimer laser is a widely used device throughout the field of dermatology for many diseases including psoriasis. Although the laser has demonstrated clinical efficacy, there is a lack of literature outlining the safety, efficacy, and patient acceptability of the excimer laser. Methods: A literature search on PubMed was used with combinations of the terms “excimer”, “excimer laser”, “308 nm”, “psoriasis”, “protocol”, “safety”, “efficacy”, acceptability”, “side effects”, and “dose”. The search results were included if they contained information pertaining to excimer laser and psoriasis treatment and description of the safety, efficacy, and patient acceptability of the treatment. Results: The 308 nm excimer laser is generally safe and well tolerated with minimal side effects including erythema, blistering, and pigmentary changes. It has a range of efficacies depending on the protocol used with several different treatment protocols, including the induration protocol, the minimal erythema dose protocol, and the newer minimal blistering dose protocol. Conclusion: Although the excimer laser is not a first-line treatment, it remains an excellent treatment option for psoriasis patients and has been demonstrated to be an effective treatment with little to no side effects. Keywords: excimer, laser, 308 nm, psoriasis, safety, efficacy

  5. Parental bonding and attitudes toward suicide among medical college students in Japan

    Directory of Open Access Journals (Sweden)

    Hashimoto K

    2014-10-01

    Full Text Available Kojiro Hashimoto,1 Norio Sugawara,2 Osamu Tanaka,2 Kazuhiko Nakamura,1 Norio Yasui-Furukori1 1Department of Neuropsychiatry, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan; 2Aomori Prefectural Center for Mental Health and Welfare, Aomori, Japan Background: Suicide is a grave public health issue that is responsible for a high mortality rate among individuals aged 15–44 years. Attitudes toward suicide among medical staff members have been associated with appropriate therapeutic responses to suicidal individuals. The aim of this study was to examine the effects of parental rearing on attitudes toward suicide among Japanese medical college students. Methods: We examined the association between parental bonding and attitudes toward suicide in 160 medical college students in Japan. The Parental Bonding Instrument was used to assess the attitudes and behaviors of parents. The attitudes toward suicide were evaluated using the Japanese version of the Attitudes Toward Suicide questionnaire. Results: The mean age of the subjects was 25.2±4.0 years old. The majority of the participants in our study agreed that anyone could commit suicide (88.8% and that suicide is preventable (86.3%. After adjusting for age and sex, multivariate regression analysis revealed that maternal care approached a statistically significant association with the “right to suicide” attitude. Under the same conditions, maternal care was shown to be significantly associated with the “common occurrence” attitude. No other significant relationships were observed between parental bonding and attitudes toward suicide.Conclusion: This study suggests that a higher level of maternal care ensures that children think that suicide occurs less commonly. The promotion of best practices for suicide prevention among medical students is needed. Child rearing support might be associated with suicide prevention.Keywords: attitudes toward suicide, Japanese, medical college

  6. Comparison of clinical features between primary and drug-induced sleep-related eating disorder

    Directory of Open Access Journals (Sweden)

    Komada Y

    2016-05-01

    Full Text Available Yoko Komada,1 Yoshikazu Takaesu,2 Kentaro Matsui,3 Masaki Nakamura,3 Shingo Nishida,3 Meri Kanno,3,† Akira Usui,3 Yuichi Inoue1,3 1Department of Somnology, 2Department of Psychiatry, Tokyo Medical University, 3Japan Somnology Center, Institute of Neuropsychiatry, Tokyo, Japan †Meri Kanno passed away on March 1, 2016 Purpose: The aim of this study was to ascertain the clinical characteristics of drug-induced sleep-related eating disorder (SRED. Patients and methods: We retrospectively reviewed the medical records of 30 patients with primary SRED (without any comorbid sleep disorders and who were not taking any possible causative medications, and ten patients with drug-induced SRED (occurrence of SRED episodes after starting nightly medication of sedative drugs, which completely resolved after dose reduction or discontinuation of the sedatives. Results: All patients with drug-induced SRED took multiple types of sedatives, such as benzodiazepines or benzodiazepine receptor agonists. Clinical features of drug-induced SRED compared with primary SRED were as follows: higher mean age of onset (40 years old in drug-induced SRED vs 26 years old in primary SRED, significantly higher rate of patients who had total amnesia during most of their SRED episodes (75.0% vs 31.8%, significantly lower rate of comorbidity of night eating syndrome (0% vs 63.3%, and significantly lower rate of history of sleepwalking (10.0% vs 46.7%. Increased doses of benzodiazepine receptor agonists may be responsible for drug-induced SRED. Conclusion: The clinical features of drug-induced SRED were different from those of primary SRED, possibly reflecting differences in the underlying mechanisms between these two categories of SREDs. Keywords: nocturnal eating syndrome, night eating, eating disorder, hypnotics, amnesia, sleepwalking, benzodiazepine

  7. False Negative Rates of a Macrofoam-Swab Sampling Method with Low Surface Concentrations of Two Bacillus anthracis Surrogates via Real-Time PCR

    Energy Technology Data Exchange (ETDEWEB)

    Hutchison, Janine R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Piepel, Gregory F. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Amidan, Brett G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Sydor, Michael A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deatherage Kaiser, Brooke L [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-05-01

    Surface sampling for Bacillus anthracis spores has traditionally relied on detection via bacterial cultivation methods. Although effective, this approach does not provide the level of organism specificity that can be gained through molecular techniques. False negative rates (FNR) and limits of detection (LOD) were determined for two B. anthracis surrogates with modified rapid viability-polymerase chain reaction (mRV-PCR) following macrofoam-swab sampling. This study was conducted in parallel with a previously reported study that analyzed spores using a plate-culture method. B. anthracis Sterne (BAS) or B. atrophaeus Nakamura (BG) spores were deposited onto four surface materials (glass, stainless steel, vinyl tile, and plastic) at nine target concentrations (2 to 500 spores/coupon; 0.078 to 19.375 colony-forming units [CFU] per cm²). Mean FNR values for mRV-PCR analysis ranged from 0 to 0.917 for BAS and 0 to 0.875 for BG and increased as spore concentration decreased (over the concentrations investigated) for each surface material. FNRs based on mRV-PCR data were not statistically different for BAS and BG, but were significantly lower for glass than for vinyl tile. FNRs also tended to be lower for the mRV-PCR method compared to the culture method. The mRV-PCR LOD₉₅ was lowest for glass (0.429 CFU/cm² with BAS and 0.341 CFU/cm² with BG) and highest for vinyl tile (0.919 CFU/cm² with BAS and 0.917 CFU/cm² with BG). These mRV-PCR LOD₉₅ values were lower than the culture values (BAS: 0.678 to 1.023 CFU/cm² and BG: 0.820 to 1.489 CFU/cm²). The FNR and LOD₉₅ values reported in this work provide guidance for environmental sampling of Bacillus spores at low concentrations.

  8. A Study on the Uncertainty of Flow-Induced Vibration in a Cross Flow over Staggered Tubes

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ji-Su; Park, Jong-Woon [Dongguk univ, Gyeong Ju (Korea, Republic of); Choi, Hyeon-Kyeong [HanNam University, Daejeon (Korea, Republic of)

    2015-05-15

    Cross-flow in many support columns of very high temperature reactor (VHTR) lower plenum would have FIV issues under high speed flow jetting from the core. For a group of multiple circular cylinders subjected to a cross-flow, three types of potential vibration mechanisms may exist: (1) Vortex-induced vibration (VIV), (2) Fluid-elastic vibration (FEV) and (3) Turbulence-induced vibration (TIV). Kevalahan studied the free vibration of circular cylinders in a tightly packed periodic square inline array of cylinders. Pandey et al. studied the flue gas flow distribution in the Low Temperature Super Heater (LTSH) tube bundles situated in second pass of a utility boiler and the phenomenon of flow induced vibration. Nakamura et al. studied flow instability of cylinder arrays resembling U-bend tubes in steam generators. The FIV evaluation is usually performed with computational fluid dynamic (CFD) analysis to obtain unknown frequency of oscillation of the multiple objects under turbulent flow and thus the uncertainty residing in the turbulence model used should be quantified. In this paper, potential FIV uncertainty arising from the turbulence phenomena are evaluated for a typical cross flow through staggered tube bundles resembling the VHTR lower plenum support columns. Flow induced vibration (FIV) is one of the important mechanical and fatigue issues in nuclear systems. Especially, cross-flow in many support structures of VHTR lower plenum would have FIV issues under highly turbulent jet flows from the core. The results show that the effect of turbulence parameters on FIV is not negligible and the uncertainty is 5 to 10%. Present method can be applied to future FIV evaluations of nuclear systems. More extensive studies on flow induced vibration in a plant scale by using more rigorous computational methods are under way.

  9. Source Mechanism of May 30, 2015 Bonin Islands, Japan Deep Earthquake (Mw7.8) Estimated by Broadband Waveform Modeling

    Science.gov (United States)

    Tsuboi, S.; Nakamura, T.; Miyoshi, T.

    2015-12-01

    May 30, 2015 Bonin Islands, Japan earthquake (Mw 7.8, depth 679.9km GCMT) was one of the deepest earthquakes ever recorded. We apply the waveform inversion technique (Kikuchi & Kanamori, 1991) to obtain slip distribution in the source fault of this earthquake in the same manner as our previous work (Nakamura et al., 2010). We use 60 broadband seismograms of IRIS GSN seismic stations with epicentral distance between 30 and 90 degrees. The broadband original data are integrated into ground displacement and band-pass filtered in the frequency band 0.002-1 Hz. We use the velocity structure model IASP91 to calculate the wavefield near source and stations. We assume that the fault is squared with the length 50 km. We obtain source rupture model for both nodal planes with high dip angle (74 degree) and low dip angle (26 degree) and compare the synthetic seismograms with the observations to determine which source rupture model would explain the observations better. We calculate broadband synthetic seismograms with these source propagation models using the spectral-element method (Komatitsch & Tromp, 2001). We use new Earth Simulator system in JAMSTEC to compute synthetic seismograms using the spectral-element method. The simulations are performed on 7,776 processors, which require 1,944 nodes of the Earth Simulator. On this number of nodes, a simulation of 50 minutes of wave propagation accurate at periods of 3.8 seconds and longer requires about 5 hours of CPU time. Comparisons of the synthetic waveforms with the observation at teleseismic stations show that the arrival time of pP wave calculated for depth 679km matches well with the observation, which demonstrates that the earthquake really happened below the 660 km discontinuity. In our present forward simulations, the source rupture model with the low-angle fault dipping is likely to better explain the observations.

  10. Influences of peers’ and family members’ body shapes on perception of body image and desire for thinness in Japanese female students

    Directory of Open Access Journals (Sweden)

    Mase T

    2015-06-01

    Full Text Available Tomoki Mase,1 Kumiko Ohara,2,3 Chiemi Miyawaki,4 Katsuyasu Kouda,5 Harunobu Nakamura2 1Department of Childhood Education, Kyoto Seibo College, Kyoto, Japan; 2Graduate School of Human Development and Environment, Kobe University, Kobe, Japan; 3Research Fellow of Japan Society for the Promotion of Science, Tokyo, Japan; 4Department of Early Childhood Education, Heian Jogakuin (St Agnes’ College, Kyoto, Japan; 5Department of Public Health, Kinki University Faculty of Medicine, Osakasayama, Japan Purpose: The present study investigated the influence of peers’ and family members’ body shapes on the perception of body image and desire for thinness in Japanese female students.Methods: The study included 342 female, Japanese university students between the ages of 18 years and 22 years. They completed an anonymous questionnaire, which included questions related to anthropometry and body perception. Eating behavior was assessed by the Japanese version of the Eating Attitude Test-26.Results: Many students overestimated their body shape (81.2% of underweight students and 74.6% of normal students and had a desire for thinness (41.0% of underweight students, 88.2% of normal students, and 100% of overweight students. One of the main reasons for the overestimation of their body shape was comparison with others. Participants who were interested in a friend’s body shape were almost three times more likely to have a desire for thinness than those who were not interested in a female friend’s body shape (odds ratio: 3.06, P=0.014.Conclusion: The results indicate a possibility that a female Japanese student’s young female friends’ body shapes, influences her desire for thinness or her perception of her own body shape. Keywords: body perception, body shape, desire for thinness, female students 

  11. Higher lung accumulation of intravenously injected organic nanotubes

    Directory of Open Access Journals (Sweden)

    Maitani Y

    2013-01-01

    Full Text Available Yoshie Maitani,1 Yuri Nakamura,1 Masao Kon,1 Emi Sanada,1 Kae Sumiyoshi,1 Natsuki Fujine,1 Masumi Asakawa,2 Masaki Kogiso,2 Toshimi Shimizu21Institute of Medicinal Chemistry, Hoshi University, Tokyo, Japan; 2Nanotube Research Center (NTRC, National Institute of Advanced Industrial Science and Technology (AIST, Tsukuba, JapanAbstract: The size and shape of intravenously injected particles can affect their biodistribution and is of importance for the development of particulated drug carrier systems. In this study, organic nanotubes (ONTs with a carboxyl group at the surface, a length of approximately 2 µm and outer diameter of 70–90 nm, were injected intravenously into tumor-bearing mice. To use ONTs as drug carriers, the biodistribution in selected organs of ONTs postinjection was examined using irinotecan, as an entrapped water-soluble marker inside ONTs, and gadolinium-chelated ONT, as an ONT marker, and compared with that of a 3 µm fluorescently labeled spherical microparticle which was similar size to the length of ONTs. It was found that for irinotecan, its active metabolite and gadolinium-chelated ONTs were highly accumulated in the lung, but to a lower level in the liver and spleen. On the other hand, microparticles deposited less in the lung and more highly in the liver. Moreover, histologic examination showed ONTs distributed more in lung tissues in part, whereas microparticles were present in blood vessels postinjection. These preliminary results support the notion of using negatively charged ONTs as intravascular carriers to maximize accumulation in the lung whilst reducing sequestration by the liver and spleen. This finding suggested that ONTs are potential carriers for lung-targeting drug delivery.Keywords: organic nanotube, lung, biodistribution, microparticle, particle shape

  12. Analysis of macular cone photoreceptors in a case of occult macular dystrophy

    Directory of Open Access Journals (Sweden)

    Tojo N

    2013-05-01

    Full Text Available Naoki Tojo Tomoko Nakamura Hironori Ozaki Miyako Oka Toshihiko Oiwake Atsushi HayashiDepartment of Ophthalmology, University of Toyama, Toyama, JapanPurpose: To investigate changes in cone photoreceptors with adaptive optics (AO fundus imaging and spectral domain optical coherence tomography (SD-OCT in a case of occult macular dystrophy (OMD.Patient and methods: Both eyes of a 42-year-old woman diagnosed with OMD were examined. We used an AO fundus camera to obtain images of cone photoreceptors in the macula of the OMD subject and five healthy control subjects. Correlations between the AO images and the SD-OCT images were examined. Cone photoreceptors in eight areas in the macula of OMD and healthy control subjects were analyzed and compared.Results: SD-OCT showed a loss of the cone outer-segment tips line outside of the fovea in both eyes of the subject with OMD. The left eye with decreased visual acuity showed a discontinuous photoreceptor inner-segment and outer-segment line and cone outer-segment tips line at the fovea in SD-OCT and loss of cone mosaics as a dark spot in the AO image. In panoramic AO images and cone-density maps, less cone density was observed in a ring-like region outside the fovea than in the peripheral retina. In most of the areas examined, the cone densities were lower in the OMD eyes than in the healthy control eyes.Conclusions: Cone densities in the macula of the OMD patient were greatly decreased. AO images were found to be useful to evaluate morphologic changes in cone photoreceptors in patients with OMD.Keywords: occult macular dystrophy, adaptive optics, cone photoreceptor, cone analysis, optical coherence tomography

  13. Repeated-Sprint Sequences During Female Soccer Matches Using Fixed and Individual Speed Thresholds.

    Science.gov (United States)

    Nakamura, Fábio Y; Pereira, Lucas A; Loturco, Irineu; Rosseti, Marcelo; Moura, Felipe A; Bradley, Paul S

    2017-07-01

    Nakamura, FY, Pereira, LA, Loturco, I, Rosseti, M, Moura, FA, and Bradley, PS. Repeated-sprint sequences during female soccer matches using fixed and individual speed thresholds. J Strength Cond Res 31(7): 1802-1810, 2017-The main objective of this study was to characterize the occurrence of single sprint and repeated-sprint sequences (RSS) during elite female soccer matches, using fixed (20 km·h) and individually based speed thresholds (>90% of the mean speed from a 20-m sprint test). Eleven elite female soccer players from the same team participated in the study. All players performed a 20-m linear sprint test, and were assessed in up to 10 official matches using Global Positioning System technology. Magnitude-based inferences were used to test for meaningful differences. Results revealed that irrespective of adopting fixed or individual speed thresholds, female players produced only a few RSS during matches (2.3 ± 2.4 sequences using the fixed threshold and 3.3 ± 3.0 sequences using the individually based threshold), with most sequences composing of just 2 sprints. Additionally, central defenders performed fewer sprints (10.2 ± 4.1) than other positions (fullbacks: 28.1 ± 5.5; midfielders: 21.9 ± 10.5; forwards: 31.9 ± 11.1; with the differences being likely to almost certainly associated with effect sizes ranging from 1.65 to 2.72), and sprinting ability declined in the second half. The data do not support the notion that RSS occurs frequently during soccer matches in female players, irrespective of using fixed or individual speed thresholds to define sprint occurrence. However, repeated-sprint ability development cannot be ruled out from soccer training programs because of its association with match-related performance.

  14. Chronological changes in lung cancer surgery in a single Japanese institution

    Directory of Open Access Journals (Sweden)

    Nakamura H

    2017-03-01

    Full Text Available Haruhiko Nakamura, Hiroki Sakai, Hiroyuki Kimura, Tomoyuki Miyazawa, Hideki Marushima, Hisashi Saji Department of Chest Surgery, St Marianna University School of Medicine, Kawasaki, Kanagawa, Japan Background: The aim of this study was to evaluate the chronological changes in epidemiological factors and surgical outcomes in patients with lung cancer who underwent surgery in a single Japanese institution.Patients and methods: A clinicopathological database of patients with lung cancer who underwent surgery with curative intent from January 1974 to December 2014 was reviewed. The chronological changes in various factors, including patient’s age, sex, histological type, tumor size, pathological stage (p-stage, surgical method, operative time, intraoperative blood loss, 30-day mortality, and postoperative overall survival (OS, were evaluated.Results: A total of 1,616 patients were included. The numbers of resected patients, females, adenocarcinomas, p-stage IA patients, and age at the time of surgery increased with time, but tumor size decreased (all P<0.0001. Concerning surgical methods, the number of sublobar resections increased, but that of pneumonectomies decreased (P<0.0001. The mean operative time, intraoperative blood loss, and the postoperative 30-day mortality rate decreased (all P<0.0001. When the patients were divided into two groups (1974–2004 and 2005–2014, the 5-year OS rates for all patients and for p-stage IA patients improved from 44% to 79% and from 73% to 89%, respectively (all P<0.0001. The best 5-year OS rate was obtained for sublobar resection (73%, followed by lobectomy (60%, combined resection (22%, and pneumonectomy (21%; P<0.0001.Conclusion: Changes in epidemiological factors, a trend toward less invasive surgery, and a remarkably improved postoperative OS were confirmed, which demonstrated the increasingly important role of surgery in therapeutic strategies for lung cancer. Keywords: lung cancer, surgery, sublobar

  15. Age-period-cohort analysis of suicides among Japanese 1950-2003: a Bayesian cohort model analysis.

    Science.gov (United States)

    Ooe, Yosuke; Ohno, Yuko; Nakamura, Takashi

    2009-07-01

    The suicide rate in Japan is one of the highest in the world and presents us with a considerable challenge. Demographic statistics show that the number of suicides is on the rise, and at roughly 30,000 people per year have committed suicide since 1998. Suicide trends are not only related to economic boom and bust but also to certain generations and age groups. During the 1950s, there was a remarkably high suicide rate among people in their 20s, and this cohort was identical to that of the middle-age generation in the 1980s. It is important to separately understand both the trend of suicide rates and the numbers analyzed to determine the different factors that influence suicide. These include age, time period, cohort, interaction between age and time period, and changes in population composition. We performed an age-period-cohort analysis of annual trends of suicide rates by age group in Japan using a Bayesian cohort model. With the help of the Nakamura method, we have been able to break down the effects of age, time period, cohort, and the age-by-period interaction. The cohort comprised of people born in the 1930s demonstrated a relatively high suicide rate. Men currently in their 50s also belong to a high suicide rate cohort. Regarding the period effect, business cycles and by-period interaction effect, it became apparent that the high suicide rate among young adults in their early 20s around 1960 was slowing, especially among men. Instead, there was an obvious recent trend for men in their late 50s to have the highest suicide rate. This study confirmed that age-period-cohort analysis can describe these trends of suicide mortality of the Japanese.

  16. Influences of Fascicle Length During Isometric Training on Improvement of Muscle Strength.

    Science.gov (United States)

    Tanaka, Hiroki; Ikezoe, Tome; Umehara, Jun; Nakamura, Masatoshi; Umegaki, Hiroki; Kobayashi, Takuya; Nishishita, Satoru; Fujita, Kosuke; Araki, Kojiro; Ichihashi, Noriaki

    2016-11-01

    Tanaka, H, Ikezoe, T, Umehara, J, Nakamura, M, Umegaki, H, Kobayashi, T, Nishishita, S, Fujita, K, Araki, K, and Ichihashi, N. Influences of fascicle length during isometric training on improvement of muscle strength. J Strength Cond Res 30(11): 3249-3255, 2016-This study investigated whether low-intensity isometric training would elicit a greater improvement in maximum voluntary contraction (MVC) at the same fascicle length, rather than the joint angle, adopted during training. Sixteen healthy women (21.8 ± 1.5 years) were randomly divided into an intervention group and a control group. Before (Pre) and after (Post) training, isometric plantarflexion MVCs were measured every 10° through the range of ankle joint position from 20° dorsiflexion to 30° plantarflexion (i.e., 6 ankle angles). Medial gastrocnemius fascicle length was also measured at each position, using B-mode ultrasound under 3 conditions of muscle activation: at rest, 30%MVC at respective angles, and MVC. Plantarflexion resistance training at an angle of 20° plantarflexion was performed 3 days a week for 4 weeks at 30%MVC using 3 sets of twenty 3-second isometric contractions. Maximum voluntary contraction in the intervention group increased at 0 and 10° plantarflexion (0°; Pre: 81.2 ± 26.5 N·m, Post: 105.0 ± 21.6 N·m, 10°; Pre: 63.0 ± 23.6 N·m, Post: 81.3 ± 20.3 N·m), which was not the angle used in training (20°). However, the fascicle length adopted in training at 20° plantarflexion and 30%MVC was similar to the value at 0 or 10° plantarflexion at MVC. Low-intensity isometric training at a shortened muscle length may be effective for improving MVC at a lengthened muscle length because of specificity of the fascicle length than the joint angle.

  17. False Negative Rates of a Macrofoam-Swab Sampling Method with Low Surface Concentrations of Two Bacillus anthracis Surrogates via Real-Time PCR

    Energy Technology Data Exchange (ETDEWEB)

    Hutchison, Janine R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Piepel, Gregory F. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Amidan, Brett G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Sydor, Michael A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kaiser, Brooke L.D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-06-01

    Surface sampling for Bacillus anthracis spores has traditionally relied on detection via bacterial cultivation methods. Although effective, this approach does not provide the level of organism specificity that can be gained through molecular techniques. False negative rates (FNR) and limits of detection (LOD) were determined for two B. anthracis surrogates with modified rapid viability-polymerase chain reaction (mRV-PCR) following macrofoam-swab sampling. This study was conducted in parallel with a previously reported study that analyzed spores using a plate-culture method. B. anthracis Sterne (BAS) or B. atrophaeus Nakamura (BG) spores were deposited onto four surface materials (glass, stainless steel, vinyl tile, and plastic) at nine target concentrations (2 to 500 spores/coupon; 0.078 to 19.375 colony-forming units [CFU] per cm2). Mean FNR values for mRV-PCR analysis ranged from 0 to 0.917 for BAS and 0 to 0.875 for BG and increased as spore concentration decreased (over the concentrations investigated) for each surface material. FNRs based on mRV-PCR data were not statistically different for BAS and BG, but were significantly lower for glass than for vinyl tile. FNRs also tended to be lower for the mRV-PCR method compared to the culture method. The mRV-PCR LOD95 was lowest for glass (0.429 CFU/cm2 with BAS and 0.341 CFU/cm2 with BG) and highest for vinyl tile (0.919 CFU/cm2 with BAS and 0.917 CFU/cm2 with BG). These mRV-PCR LOD95 values were lower than the culture values (BAS: 0.678 to 1.023 CFU/cm2 and BG: 0.820 to 1.489 CFU/cm2). The FNR and LOD95 values reported in this work provide guidance for environmental sampling of Bacillus spores at low concentrations.

  18. Site Effect and Expected Seismic Performance of Buildings in Palestine- Case Study: Nablus City

    International Nuclear Information System (INIS)

    Al-Dabbeek, Jalal N.; El-Kelani, Radwan J.

    2008-01-01

    The effects of local geology on ground-motion amplification and building damage were studied in Palestine-West Bank. Nakamura's method of microtremor analysis was applied in this study. The measurements showed significantly higher amplification in the frequency range of building vulnerability in different parts of Nablus city. This finding is consistent with the distribution of the earthquake damage grades in the urban areas struck by the 11 February 2004 earthquake (ML = 5.2) with a focal depth of 17 km beneath the northeastern part of the Dead Sea Basin. Quite large differences in amplification between around 1 and 9 were computed between the eastern and western rims of the city. The downtown built in the central part of the city on soft clay, marl and valley deposits, whereas the northern and southern parts of urban areas in Nablus city lying on mountains consist of consolidated carbonates bedrock. In the central part of the city and at the rims, where the thickness of fluvial deposits and soft formations is about 15 m, amplifications between 6.74 and 8.67 for dominant natural period range of 0.8-1.1 sec were obtained. On the southern and northern mountains, which are located on limestone rocks covered with a thin layer of soil, the amplification in the same frequency range was low. Calculating the natural period of the existing common buildings (T b ) in the studied area (buildings with 10-12 stories), by using the dynamic analysis method. The values of T b obtained were much closed to the site dominant natural period (Ts). The findings of this study indicate that the expected differences in damage grades for urban areas in Nablus city could be attributed to variations in the thickness and physical properties of Tertiary-Quaternary sediments, which appear to be rather heterogeneous

  19. Site response assessment at the city of Alkhobar, Eastern Saudi Arabia from microtremor and boring data

    Science.gov (United States)

    Fnais, M. S.

    2014-12-01

    The AlKhobar City affected by distant earthquakes from Zagros fold-fault belt of subduction zone. These earthquakes produced great site effects on the sedimentary layers that in turn significantly influenced earthquake ground motions in the area. Mapping of site response using microtremor measurements compared with geological and borehole data of Alkhobar city is the main target of this work. The resonance frequency and their H/V values have been calculated using Nakamura technique through deployed of seismograph instruments at 113 sites in AlKhobar city for different time periods. The recording length was about one hour with sampling frequency of 100 Hz. Most of the measured sites present three peaks for the resonance frequency; the first peak ranges from 0.33 to 1.03 Hz, the second peak ranges from 1.03 to 1.23 Hz, while the third peak ranges from 1.23-1.73. Tests have been conducted to ensure that these peaks are natural in origin. The northern zones of AlKhobar City have lower values of resonance frequency indicating great thickness of sediments. In contrast, the southern parts of the city have higher values of resonance frequency illustrating shallow depths of the bedrock. Furthermore, twenty of boreholes have been conducted through AlKhobar City to different depth. Standard penetration test (SPT) data has been corrected and used to calculate the resonance frequency at their locations. Borehole results clarified that the resonance frequency values range from 0.27 to 1.95 Hz. These results are correlated well with that of the microtremor measurements. Accordingly, the first peak have been interpreted due to the impedance contrast between the limestone and the overlying sediments, while the third peak is originated from a boundary between the upper most surface layer and the underlying sediments. These results must be applied for earthquake risk mitigation in AlKhobar City.

  20. Analysis of Tropical Cyclone Tracks in the North Indian Ocean

    Science.gov (United States)

    Patwardhan, A.; Paliwal, M.; Mohapatra, M.

    2011-12-01

    Cyclones are regarded as one of the most dangerous meteorological phenomena of the tropical region. The probability of landfall of a tropical cyclone depends on its movement (trajectory). Analysis of trajectories of tropical cyclones could be useful for identifying potentially predictable characteristics. There is long history of analysis of tropical cyclones tracks. A common approach is using different clustering techniques to group the cyclone tracks on the basis of certain characteristics. Various clustering method have been used to study the tropical cyclones in different ocean basins like western North Pacific ocean (Elsner and Liu, 2003; Camargo et al., 2007), North Atlantic Ocean (Elsner, 2003; Gaffney et al. 2007; Nakamura et al., 2009). In this study, tropical cyclone tracks in the North Indian Ocean basin, for the period 1961-2010 have been analyzed and grouped into clusters based on their spatial characteristics. A tropical cyclone trajectory is approximated as an open curve and described by its first two moments. The resulting clusters have different centroid locations and also differently shaped variance ellipses. These track characteristics are then used in the standard clustering algorithms which allow the whole track shape, length, and location to be incorporated into the clustering methodology. The resulting clusters have different genesis locations and trajectory shapes. We have also examined characteristics such as life span, maximum sustained wind speed, landfall, seasonality, many of which are significantly different across the identified clusters. The clustering approach groups cyclones with higher maximum wind speed and longest life span in to one cluster. Another cluster includes short duration cyclonic events that are mostly deep depressions and significant for rainfall over Eastern and Central India. The clustering approach is likely to prove useful for analysis of events of significance with regard to impacts.

  1. Solid state NMR, basic theory and recent progress for quadrupole nuclei with half-integer spin

    International Nuclear Information System (INIS)

    Dieter, F.

    1998-01-01

    This review describes the basic theory and some recently developed techniques for the study of quadrupole nuclei with half integer spins in powder materials. The latter is connected to the introduction of the double rotation (DOR) by A. Samoson et al. (1) and to the introduction of the multiple quantum magic-angle spinning (MQ MAS) technique by L. Frydman et. al. (2). For integer spins, especially the solid-state deuterium magnetic resonance, we refer to the review of G.L. Hoatson and R.L. Vold: '' 2 H-NMR Spectroscopy of Solids and Liquid Crystals'' (3). For single crystals we refer to O. Kanert and M. Mehring: ''Static quadrupole effects in disordered cubic solids''(4) and we would like also to mention the ''classic'' review of M.H. Cohen and F. Reif: ''Quadrupole effects in NMR studies of solids'' (5). Some more recent reviews in the field under study are D. Freude and J. Haase ''Quadrupole effects in solid-state NMR'' (6). Ch. Jager: ''Satellite Transition Spectroscopy of Quadrupolar Nuclei'' (7) and B.F. Chmelka and J.W. Zwanziger: ''Solid State NMR Line Narrowing Methods for Quadrupolar Nuclei - Double Rotation and Dynamic-Angle Spinning'' (8). A survey of nuclear quadrupole frequency data published before the end of 1982 is given by H. Chihara and N. Nakamura in Landolt-Bornstein, Vol. 20 (9). Values of the chemical shift of quadrupole nuclei in solids can be found in books such as ''Multinuclear NMR'' edited by J. Mason (10). In section 9 of ref (6) some electric field gradient and chemical shift data published from 1983 to 1992 for the most studied quadrupole nuclei sup 27 Al, sup 23 Na, and sup 17 O are given

  2. Analysis shear wave velocity structure obtained from surface wave methods in Bornova, Izmir

    Energy Technology Data Exchange (ETDEWEB)

    Pamuk, Eren, E-mail: eren.pamuk@deu.edu.tr; Akgün, Mustafa, E-mail: mustafa.akgun@deu.edu.tr [Department of Geophysical Engineering, Dokuz Eylul University, Izmir (Turkey); Özdağ, Özkan Cevdet, E-mail: cevdet.ozdag@deu.edu.tr [Dokuz Eylul University Rectorate, Izmir (Turkey)

    2016-04-18

    Properties of the soil from the bedrock is necessary to describe accurately and reliably for the reduction of earthquake damage. Because seismic waves change their amplitude and frequency content owing to acoustic impedance difference between soil and bedrock. Firstly, shear wave velocity and depth information of layers on bedrock is needed to detect this changing. Shear wave velocity can be obtained using inversion of Rayleigh wave dispersion curves obtained from surface wave methods (MASW- the Multichannel Analysis of Surface Waves, ReMi-Refraction Microtremor, SPAC-Spatial Autocorrelation). While research depth is limeted in active source study, a passive source methods are utilized for deep depth which is not reached using active source methods. ReMi method is used to determine layer thickness and velocity up to 100 m using seismic refraction measurement systems.The research carried out up to desired depth depending on radius using SPAC which is utilized easily in conditions that district using of seismic studies in the city. Vs profiles which are required to calculate deformations in under static and dynamic loads can be obtained with high resolution using combining rayleigh wave dispersion curve obtained from active and passive source methods. In the this study, Surface waves data were collected using the measurements of MASW, ReMi and SPAC at the İzmir Bornova region. Dispersion curves obtained from surface wave methods were combined in wide frequency band and Vs-depth profiles were obtained using inversion. Reliability of the resulting soil profiles were provided by comparison with theoretical transfer function obtained from soil paremeters and observed soil transfer function from Nakamura technique and by examination of fitting between these functions. Vs values are changed between 200-830 m/s and engineering bedrock (Vs>760 m/s) depth is approximately 150 m.

  3. Seismic ground motion characteristics in the Bucharest area: source and site effects contribution

    International Nuclear Information System (INIS)

    Grecu, B.; Popa, M.; Radulian, M.

    2003-01-01

    The contribution of source vs. site effects on the seismic ground motion in Bucharest is controversial as the previous studies showed. The fundamental period of resonance for the sedimentary cover is emphasized by ambient noise and earthquake measurements, if the spectral ratio method (Nakamura, 1989) is applied (Bonjer et al., 1989). On the other hand, the numerical simulations (Moldoveanu et al., 2000.) and acceleration spectra analysis (Sandi et al., 2001) brought into the light the determinant role of the source effects. We considered all the available instrumental data related to Vrancea earthquakes recorded in Bucharest area to find how the source and site properties control the peak ground motion peculiarities. Our main results are summarized as follows: 1. The resonant period of oscillation, related to the shallow sediment layer, is practically present in all the H/V spectral ratios, no matter we consider ambient noise or earthquakes of any size. This argues in favor of the crucial role played by the sedimentary cover and proves that the ratio method is reasonably removing the source effects. However, the absolute spectra are completely different for earthquakes below and above magnitude 7, namely amplitudes in the range of 1-2 s periods are negligible in the first case, and predominant in the second one. It looks like the resonant amplification by the sedimentary cover becomes effective only for the largest earthquakes (M > 7), when the source radiation coincides with the fundamental resonance range. We conclude that the damage in Bucharest is dramatically amplified when the earthquake size is above a critical value (M ≅ 7); 2. Our analysis shows a rather weak variability of the peak motion values and spectral amplitudes over the study area, in agreement with the relatively small variability of the shallow structure topography. (authors)

  4. Electrochemical CO2 Reduction by Ni-containing Iron Sulfides: How Is CO2 Electrochemically Reduced at Bisulfide-Bearing Deep-sea Hydrothermal Precipitates?

    International Nuclear Information System (INIS)

    Yamaguchi, Akira; Yamamoto, Masahiro; Takai, Ken; Ishii, Takumi; Hashimoto, Kazuhito; Nakamura, Ryuhei

    2014-01-01

    The discovery of deep-sea hydrothermal vents on the late 1970's has led to many hypotheses concerning chemical evolution in the prebiotic ocean and the early evolution of energy metabolism in ancient Earth. Such studies stand on the quest for the bioenergetic evolution to utilize reducing chemicals such as H 2 for CO 2 reduction and carbon assimilation. In addition to the direct reaction of H 2 and CO 2 , the electrical current passing across a bisulfide-bearing chimney structure has pointed to the possible electrocatalytic CO 2 reduction at the cold ocean-vent interface (R. Nakamura, et al. Angew. Chem. Int. Ed. 2010, 49, 7692 − 7694). To confirm the validity of this hypothesis, here, we examined the energetics of electrocatalytic CO 2 reduction by iron sulfide (FeS) deposits at slightly acidic pH. Although FeS deposits inefficiently reduced CO 2 , the efficiency of the reaction was substantially improved by the substitution of Fe with Ni to form FeNi 2 S 4 (violarite), of which surface was further modified with amine compounds. The potential-dependent activity of CO 2 reduction demonstrated that CO 2 reduction by H 2 in hydrothermal fluids was involved in a strong endergonic electron transfer reaction, suggesting that a naturally occurring proton-motive force (PMF) as high as 200 mV would be established across the hydrothermal vent chimney wall. However, in the chimney structures, H 2 generation competes with CO 2 reduction for electrical current, resulting in rapid consumption of the PMF. Therefore, to maintain the PMF and the electrosynthesis of organic compounds in hydrothermal vent mineral deposits, we propose a homeostatic pH regulation mechanism of FeS deposits, in which elemental hydrogen stored in the hydrothermal mineral deposits is used to balance the consumption of the electrochemical gradient by H 2 generation

  5. Adaptive optics fundus images of cone photoreceptors in the macula of patients with retinitis pigmentosa

    Directory of Open Access Journals (Sweden)

    Tojo N

    2013-01-01

    Full Text Available Naoki Tojo, Tomoko Nakamura, Chiharu Fuchizawa, Toshihiko Oiwake, Atsushi HayashiDepartment of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, JapanBackground: The purpose of this study was to examine cone photoreceptors in the macula of patients with retinitis pigmentosa using an adaptive optics fundus camera and to investigate any correlations between cone photoreceptor density and findings on optical coherence tomography and fundus autofluorescence.Methods: We examined two patients with typical retinitis pigmentosa who underwent ophthalmological examination, including measurement of visual acuity, and gathering of electroretinographic, optical coherence tomographic, fundus autofluorescent, and adaptive optics fundus images. The cone photoreceptors in the adaptive optics images of the two patients with retinitis pigmentosa and five healthy subjects were analyzed.Results: An abnormal parafoveal ring of high-density fundus autofluorescence was observed in the macula in both patients. The border of the ring corresponded to the border of the external limiting membrane and the inner segment and outer segment line in the optical coherence tomographic images. Cone photoreceptors at the abnormal parafoveal ring were blurred and decreased in the adaptive optics images. The blurred area corresponded to the abnormal parafoveal ring in the fundus autofluorescence images. Cone densities were low at the blurred areas and at the nasal and temporal retina along a line from the fovea compared with those of healthy controls. The results for cone spacing and Voronoi domains in the macula corresponded with those for the cone densities.Conclusion: Cone densities were heavily decreased in the macula, especially at the parafoveal ring on high-density fundus autofluorescence in both patients with retinitis pigmentosa. Adaptive optics images enabled us to observe in vivo changes in the cone photoreceptors of

  6. IDENTIFICACIÓN DEL AGENTE CAUSAL DE LA ANTRACNOSIS DE Sansevieria spp. EN COSTA RICA

    Directory of Open Access Journals (Sweden)

    Gerardo Pérez-León

    2013-01-01

    Full Text Available Sansevieria spp. (Agavaceae es una ornamental de follaje originaria de África y Asia. S. trifasciata (St es la especie con mayor número de cultivares en el mercado de exportación de Costa Rica a Estados Unidos y Holanda. Muestras foliares de S. trifasciata var. “Hahnii” con lesiones circulares y acuosas (algunas alargadas y secas, fueron analizadas. El patógeno recuperado fue identificado como Colletotrichum sansevieriae Nakamura (CsN mediante pruebas de patogenicidad, morfología y técnicas moleculares. Los aislamientos mono-hifales presentaron coloración crema, crecimiento postrado y escasa producción de conidios. La patogenicidad de CsN se evaluó en 7 variedades de St; Sansevieriasp., var., jiboia; S. cylindrica y las ornamentalesCodiaeum variegatum, Cordelyne terminalis y Dracaena deremensis, mediante 2 sistemas deinoculación: plantas en maceta (invernaderoy hojas separadas (laboratorio; con ambos sereprodujeron los síntomas de la enfermedad. Cinco de las variedades de S. trifasciata desarrollaron síntomas, “Hahnii” la más susceptible. Ninguna de las otras ornamentales presentósíntomas. CsN fue re-aislado de hojas inoculadas (postulados de Koch. La amplificación mediante PCR de la región ITS con los iniciadores ITS5 e ITS4 produjo un fragmento de aproximadamente 600pb, cuya secuencia de nucleótidos fue idéntica para los aislamientos mono-hifales. En el Banco de Genes, la secuencia alineó con accesiones de CsN de Australia y USA, con un índice de simi laridad del 99 al 100%. El análisis filogenético, con base en la región ITS2, agrupó (99% valor debootstrap los aislamientos costarricenses con elaislamiento tipo CsN de Japón y los de Australia y USA. Hasta donde se conoce, éste es el primer informe de la antracnosis de Sansevieria en C. R.

  7. Interlinked population balance and cybernetic models for the simultaneous saccharification and fermentation of natural polymers.

    Science.gov (United States)

    Ho, Yong Kuen; Doshi, Pankaj; Yeoh, Hak Koon; Ngoh, Gek Cheng

    2015-10-01

    Simultaneous Saccharification and Fermentation (SSF) is a process where microbes have to first excrete extracellular enzymes to break polymeric substrates such as starch or cellulose into edible nutrients, followed by in situ conversion of those nutrients into more valuable metabolites via fermentation. As such, SSF is very attractive as a one-pot synthesis method of biological products. However, due to the co-existence of multiple biochemical steps, modeling SSF faces two major challenges. The first is to capture the successive chain-end and/or random scission of the polymeric substrates over time, which determines the rate of generation of various fermentable substrates. The second is to incorporate the response of microbes, including their preferential substrate utilization, to such a complex broth. Each of the above-mentioned challenges has manifested itself in many related areas, and has been competently but separately attacked with two diametrically different tools, i.e., the Population Balance Modeling (PBM) and the Cybernetic Modeling (CM), respectively. To date, they have yet to be applied in unison on SSF resulting in a general inadequacy or haphazard approaches to examine the dynamics and interactions of depolymerization and fermentation. To overcome this unsatisfactory state of affairs, here, the general linkage between PBM and CM is established to model SSF. A notable feature is the flexible linkage, which allows the individual PBM and CM models to be independently modified to the desired levels of detail. A more general treatment of the secretion of extracellular enzyme is also proposed in the CM model. Through a case study on the growth of a recombinant Saccharomyces cerevisiae capable of excreting a chain-end scission enzyme (glucoamylase) on starch, the interlinked model calibrated using data from the literature (Nakamura et al., Biotechnol. Bioeng. 53:21-25, 1997), captured features not attainable by existing approaches. In particular, the effect

  8. Effects of Two Different Volume-Equated Weekly Distributed Short-Term Plyometric Training Programs on Futsal Players' Physical Performance.

    Science.gov (United States)

    Yanci, Javier; Castillo, Daniel; Iturricastillo, Aitor; Ayarra, Rubén; Nakamura, Fábio Y

    2017-07-01

    Yanci, J, Castillo, D, Iturricastillo, A, Ayarra, R, and Nakamura, FY. Effects of two different volume-equated weekly distributed short-term plyometric training programs on futsal players' physical performance. J Strength Cond Res 31(7): 1787-1794, 2017-The aim was to analyze the effect of 2 different plyometric training programs (i.e., 1 vs. 2 sessions per week, same total weekly volume) on physical performance in futsal players. Forty-four futsal players were divided into 3 training groups differing in weekly plyometric training load: the 2 days per week plyometric training group (PT2D, n = 15), the 1 day per week plyometric training group (PT1D, n = 12), and the control group (CG, n = 12) which did not perform plyometric training. The results of this study showed that in-season futsal training per se was capable of improving repeat sprint ability (RSA) (effect size [ES] = -0.59 to -1.53). However, while change of direction ability (CODA) was maintained during the training period (ES = 0.00), 15-m sprint (ES = 0.73), and vertical jump (VJ) performance (ES = -0.30 to -1.37) were significantly impaired. By contrast, PT2D and PT1D plyometric training were effective in improving futsal players' 15-m sprint (ES = -0.64 to -1.00), CODA (ES = -1.83 to -5.50), and horizontal jump (ES = 0.33-0.64) performance. Nonetheless, all groups (i.e., PT2D, PT1D, and CG) presented a reduction in VJ performance (ES = -0.04 to -1.37). Regarding RSA performance, PT1D showed a similar improvement compared with CG (ES = -0.65 to -1.53) after the training intervention, whereas PT2D did not show significant change (ES = -0.04 to -0.38). These results may have considerable practical relevance for the optimal design of plyometric training programs for futsal players, given that a 1-day-per-week plyometric training program is more efficient than a 2-day-per-week plyometric training program to improve the futsal players' physical performance.

  9. Reinvestigation of moving punctured black holes with a new code

    International Nuclear Information System (INIS)

    Cao Zhoujian; Yo Hweijang; Yu Juiping

    2008-01-01

    We report on our code, in which the moving puncture method is applied and an adaptive/fixed mesh refinement is implemented, and on its preliminary performance on black hole simulations. Based on the Baumgarte-Sharpiro-Shibata-Nakamura (BSSN) formulation, up-to-date gauge conditions and the modifications of the formulation are also implemented and tested. In this work, we present our primary results about the simulation of a single static black hole, of a moving single black hole, and of the head-on collision of a binary black hole system. For the static punctured black hole simulations, different modifications of the BSSN formulation are applied. It is demonstrated that both the currently used sets of modifications lead to a stable evolution. For cases of a moving punctured black hole with or without spin, we search for viable gauge conditions and study the effect of spin on the black hole evolution. Our results confirm previous results obtained by other research groups. In addition, we find a new gauge condition, which has not yet been adopted by any other researchers, which can also give stable and accurate black hole evolution calculations. We examine the performance of the code for the head-on collision of a binary black hole system, and the agreement of the gravitational waveform it produces with that obtained in other works. In order to understand qualitatively the influence of matter on the binary black hole collisions, we also investigate the same head-on collision scenarios but perturbed by a scalar field. The numerical simulations performed with this code not only give stable and accurate results that are consistent with the works by other numerical relativity groups, but also lead to the discovery of a new viable gauge condition, as well as clarify some ambiguities in the modification of the BSSN formulation. These results demonstrate that this code is reliable and ready to be used in the study of more realistic astrophysical scenarios and of numerical

  10. Ground Characterization Studies in Canakkale Pilot Site of LIQUEFACT Project

    Science.gov (United States)

    Ozcep, F.; Oztoprak, S.; Aysal, N.; Bozbey, I.; Tezel, O.; Ozer, C.; Sargin, S.; Bekin, E.; Almasraf, M.; Cengiz Cinku, M.; Ozdemir, K.

    2017-12-01

    The our aim is to outline the ground characterisation studies in Canakkale test site. Study is based on the EU H2020 LIQUEFACT project entitled "Liquefact: Assessment and mitigation of liquefaction potential across Europe: a holistic approach to protect structures / infrastructures for improved resilience to earthquake-induced liquefaction disasters". Objectives and extent of ground characterization for Canakkale test site includes pre-existing soil investigation studies and complementary field studies. There were several SPT and geophysical tests carried out in the study area. Within the context of the complementary tests, six (6) study areas in the test site were chosen and complementary tests were carried out in these areas. In these areas, additional boreholes were opened and SPT tests were performed. It was decided that additional CPT (CPTU and SCPT) and Marchetti Dilatometer (DMT) tests should be carried out within the scope of the complementary testing. Seismic refraction, MASW and micro tremor measurements had been carried out in pre-existing studies. Shear wave velocities obtained from MASW measurements were evaluated to the most rigorous level. These tests were downhole seismic, PS-logging, seismic refraction, 2D-ReMi, MASW, micro tremor (H/V Nakamura method), 2D resistivity and resonance acoustic profiling (RAP). RAP is a new technique which will be explained briefly in the relevant section. Dynamic soil properties had not been measured in pre-existing studies, therefore these properties were investigated within the scope of the complementary tests. Selection of specific experimental tests of the complementary campaign was based on cost-benefit considerations Within the context of complementary field studies, dynamic soil properties were measured using resonant column and cyclic direct shear tests. Several sieve analyses and Atterberg Limits tests which were documented in the pre-existing studies were evaluated. In the complementary study carried out

  11. Predisposition for borderline personality disorder with comorbid major depression is associated with that for polycystic ovary syndrome in female Japanese population

    Directory of Open Access Journals (Sweden)

    Kawamura S, Maesawa C, Nakamura K, Nakayama K, Morita M, Hiruma Y, Yoshida T, Sakai A, Masuda T

    2011-11-01

    Full Text Available Satoshi Kawamura1, Chihaya Maesawa2, Koji Nakamura1, Kazuhiko Nakayama1, Michiaki Morita1, Yohei Hiruma1, Tomoyuki Yoshida3, Akio Sakai3, Tomoyuki Masuda41Department of Psychiatry, Tokyo Jikei University school of Medicine, Tokyo, Japan; 2Department of Tumor Biology, Division of Bioscience, center for Advanced Medical science, Iwate Medical University school of Medicine, Morioka, Japan; 3Department of Neuropsychiatry, Iwate Medical University school of Medicine, Morioka, Japan; 4Department of Pathology, Iwate Medical University school of Medicine, Morioka, JapanAbstract: Polycystic ovary syndrome (PCOS is a common lifestyle-related endocrinopathy in women of reproductive age and is associated with several mental health problems. We examined the genotypic distributions of IRS-1 Gly972Arg and CYP11B2 -344T/C, which were previously described as influencing PCOS, and assayed the serum levels of interleukin-6 (IL-6 and tumor necrosis factor-alpha (TNF-α, in a set of female patients with borderline personality disorder (BPD with comorbid major depressive disorder (MDD (n = 50 and age-matched control subjects (n = 100, to investigate the predisposition for BPD with MDD. The results showed that the patients were more frequently IRS-1 972Arg variant allele carriers (P = 0.013; OR 6.68; 95% CI = 1.30-34.43 and homozygous for the CYP11B2 -344C variant allele (P = 0.022; OR = 3.32; 95% CI = 1.18-9.35 than the control subjects. The IL-6 level was significantly higher in the patients than in the controls (P < 0.0001. There was no significant difference in the serum TNF-α level between patients with BPD with MDD and the healthy comparison group (P = 0.5273. In conclusion, the predisposition for BPD with MDD is associated with that for PCOS, in the female Japanese population. An elevated serum IL-6 level is considered to be a possible biomarker of BPD with MDD.Keywords: borderline personality disorder, depression, polycystic ovary syndrome, genetic

  12. Similarity of hydrolyzing activity of human and rat small intestinal disaccharidases

    Directory of Open Access Journals (Sweden)

    Oku T

    2011-06-01

    Full Text Available Tsuneyuki Oku¹, Kenichi Tanabe¹, Shigeharu Ogawa², Naoki Sadamori¹, Sadako Nakamura¹¹Graduate School of Human Health Science, University of Nagasaki, Siebold, Nagayo, Japan; ²Juzenkai Hospital, Kagomachi, Nagasaki, JapanBackground: The purpose of this study was to clarify whether it is possible to extrapolate results from studies of the hydrolyzing activity of disaccharidases from rats to humans.Materials and methods: We measured disaccharidase activity in humans and rats using identical preparation and assay methods, and investigated the similarity in hydrolyzing activity. Small intestinal samples without malignancy were donated by five patients who had undergone bladder tumor surgery, and homogenates were prepared to measure disaccharidase activity. Adult rat homogenates were prepared using small intestine.Results: Maltase activity was the highest among the five disaccharidases, followed by sucrase and then palatinase in humans and rats. Trehalase activity was slightly lower than that of palatinase in humans and was similar to that of sucrase in rats. Lactase activity was the lowest in humans, but was similar to that of palatinase in rats. Thus, the hydrolyzing activity of five disaccharidases was generally similar in humans and rats. The relative activity of sucrose and palatinase versus maltase was generally similar between humans and rats. The ratio of rat to human hydrolyzing activity of maltase, sucrase, and palatinase was 1.9–3.1, but this was not a significant difference. Leaf extract from Morus alba strongly inhibited the activity of maltase, sucrase, and palatinase, but not trehalase and lactase, and the degree of inhibition was similar in humans and rats. L-arabinose mildly inhibited sucrase activity, but hardly inhibited the activity of maltase, palatinase, trehalase and lactase in humans and rats. The digestibility of 1-kestose, galactosylsucrose, and panose by small intestinal enzymes was very similar between humans and

  13. Potential Application of Environmental Noise Recordings in Geoarchaeological Site Characterization

    Science.gov (United States)

    Di Luzio, E.

    2015-12-01

    Environmental noise recordings are commonly applied in seismic microzonation studies. By calculating the H/V spectral ratio, the fundamental frequency of soft terrains overlying a rigid bedrock can be determined (Nakamura (1989). In such a simple two-layer system, equation f = n Vs/4H (1) links the resonance frequency "f" to the thickness "H" and shear waves velocity "Vs "of the resonating layer. In recent years, this methodology has been applied generally to obtain information on the seismostratigraphy of an investigated site in different environmental context. In this work, its potential application in the characterization of archaeological features hosted in shallow geological levels is discussed. Field cases are identified in the Appia Antica archaeological site which is placed in central Italy. Here, acknowledged targets correspond to: i) empty tanks carved by the Romans into Cretaceous limestone in the IV-III cen. BC and ii): the basaltic stone paving of the ancient road track which is locally buried beneath colluvial deposits. Narrowly-spaced recordings of environmental noise were carried using a portable digital seismograph equipped with three electrodynamic orthogonal sensors (velocimeters) responding in the band 0.1 ÷1024 Hz and adopting a sampling frequency of 256 Hz.. Results are discussed in terms of absolute H/V values and related distribution maps in the very high-frequency interval of 10-40Hz. In the tanks hosting area, interpolation of H/V maximum values around 13Hz matches caves location and alignment, which is also evidenced by clear inversions (H/V<1) at lower frequencies (10-1Hz). Correlation between H/V peaks and the top surface of the buried stone paving along the prosecution of the road track is even more straightforward. Finally, the depth variations of the tank roofs and the basaltic paving were reconstructed combining in equation (1) results of noise recordings with borehole data and geophysical surveys (SASW analysis).

  14. Comparison of DLK incidence after laser in situ keratomileusis associated with two femtosecond lasers: Femto LDV and IntraLase FS60

    Directory of Open Access Journals (Sweden)

    Tomita M

    2013-07-01

    Full Text Available Minoru Tomita,1–3 Yuko Sotoyama,1 Satoshi Yukawa,1 Tadayuki Nakamura1 1Shinagawa LASIK Center, Chiyoda-ku, Tokyo, Japan; 2Department of Ophthalmology, Wenzhou Medical College, Wenzhou, People’s Republic of China; 3Eye Can Cataract Surgery Center, Manila, Philippines Purpose: To compare the incidence of diffuse lamellar keratitis (DLK after laser in situ keratomileusis (LASIK with flap creation using the Femto LDV and IntraLase™ FS60 femtosecond lasers. Methods: A total of 818 consecutive myopic eyes had LASIK performed using either Femto LDV or IntraLase FS60 for flap creation. The same excimer laser, the Allegretto Wave® Eye-Q Laser, was used for correcting refractive errors for all patients. In the preoperative examination, uncorrected distance visual acuity, corrected distance visual acuity, and manifest refraction spherical equivalent were measured. At the postop examination, the same examinations were performed along with a slit-lamp biomicroscopic examination, and patients with DLK were classified into stages. For the statistical analysis of the DLK occurrence rate and the visual and refractive outcomes, the Mann-Whitney’s U-test was used. Results: In the Femto LDV group with 514 eyes, 42 (8.17% had DLK. In the IntraLase FS60 group with 304 eyes, 114 (37.5% had DLK. There was a statistically significant difference in the DLK incidence rate between these groups (P < 0.0001. Both groups had excellent visual and refractive outcomes. Although low levels of DLK were observed for both groups, they did not affect visual acuity. Conclusion: While there were significantly fewer incidences of low level DLK when using Femto LDV, neither femtosecond laser induced high levels of DLK, and any postoperative DLK cleared up within 1 week. Therefore, both lasers provide excellent results, with no clinical differences, and both excel at flap creation for LASIK. Keywords: LASIK, Ziemer, Femto LDV, DLK, IntraLase FS60, femtosecond laser

  15. Tyrosine levels are associated with insulin resistance in patients with nonalcoholic fatty liver disease

    Directory of Open Access Journals (Sweden)

    Kawanaka M

    2015-06-01

    Full Text Available Miwa Kawanaka,1 Ken Nishino,1 Takahito Oka,1 Noriyo Urata,1 Jun Nakamura,1 Mitsuhiko Suehiro,1 Hirofumi Kawamoto,1 Yasutaka Chiba,2 Gotaro Yamada1 1Department of General Internal Medicine 2, Kawasaki Hospital, Kawasaki Medical School, Okayama, Japan; 2Clinical Research Center, Kinki University Hospital, Sayama, Japan Objective: Amino acid imbalance is often found in patients with cirrhosis, and this imbalance is associated with insulin resistance. However, the mechanism underlying the relationship between amino acid imbalance and insulin resistance remains unclear. We evaluated serum amino acid concentrations in patients with nonalcoholic fatty liver disease to determine if any of the levels of amino acids were associated with the biochemical markers and fibrosis stage of nonalcoholic steatohepatitis (NASH. Methods: In 137 patients with nonalcoholic fatty liver disease who underwent liver biopsy, plasma levels of branched-chain amino acid (BCAA, tyrosine (Tyr, and the BCAA-to-Tyr ratio values were determined using mass spectroscopy. These values were then assessed for associations with fibrosis stage, anthropometric markers (age, sex, and body mass index, biochemical markers (alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transpeptidase, albumin, platelet count, total cholesterol, triglycerides, low-density lipoprotein cholesterol, and glycosylated hemoglobin, and relevant disease-specific biomarkers (homeostasis model assessment of insulin resistance [HOMA-IR], serum iron, ferritin, leptin, adiponectin, high-sensitivity C-reactive protein, and hyaluronic acid. Results: Serum albumin levels, plasma BCAA levels, and BCAA-to-Tyr ratio values were negatively associated with the fibrosis stage. In contrast, Tyr levels increased with increasing fibrotic staging. Tyr levels were also correlated with HOMA-IR results. Conclusion: Plasma BCAA levels in patients with NASH decreased with increasing liver fibrosis, while Tyr levels

  16. Repeating Deep Very Low Frequency Earthquakes: An Evidence of Transition Zone between Brittle and Ductile Zone along Plate Boundary

    Science.gov (United States)

    Ishihara, Y.; Yamamoto, Y.; Arai, R.

    2017-12-01

    Recently slow or low frequency seismic and geodetic events are focused under recognition of important role in tectonic process. The most western region of Ryukyu trench, Yaeyama Islands, is very active area of these type events. It has semiannual-like slow slip (Heki et.al., 2008; Nishimura et.al.,2014) and very frequent shallow very low frequency earthquakes near trench zone (Ando et.al.,2012; Nakamura et.al.,2014). Arai et.al.(2016) identified clear reverse phase discontinuity along plate boundary by air-gun survey, suggesting existence of low velocity layer including fluid. The subducting fluid layer is considered to control slip characteristics. On the other hand, deep low frequency earthquake and tremor observed at south-western Honshu and Shikoku of Japan are not identified well due to lack of high-quality seismic network. A broadband seismic station(ISG/PS) of Pacific21 network is operating in last 20 years that locates on occurrence potential area of low frequency earthquake. We tried to review continuous broadband record, searching low frequency earthquakes. In pilot survey, we found three very low frequency seismic events which are dominant in less than 0.1Hz component and are not listed in earthquake catalogue. Source locates about 50km depth and at transition area between slow slip event and active area of general earthquake along plate boundary. To detect small and/or hidden very low frequency earthquake, we applied matched filter analysis to continuous three components waveform data using pre-reviewed seismogram as template signal. 12 events with high correlation are picked up in last 10 years. Most events have very similar waveform, which means characteristics of repeating deep very low frequency earthquake. The event history of very low frequency earthquake is not related with one of slow slip event in this region. In Yaeyama region, low frequency earthquake, general earthquake and slow slip event occur dividing in space and have apparent

  17. In situ detection, isolation, and physiological properties of a thin filamentous microorganism abundant in methanogenic granular sludges: a novel isolate affiliated with a clone cluster, the green non-sulfur bacteria, subdivision I.

    Science.gov (United States)

    Sekiguchi, Y; Takahashi, H; Kamagata, Y; Ohashi, A; Harada, H

    2001-12-01

    We previously showed that very thin filamentous bacteria affiliated with the division green non-sulfur bacteria were abundant in the outermost layer of thermophilic methanogenic sludge granules fed with sucrose and several low-molecular-weight fatty acids (Y. Sekiguchi, Y. Kamagata, K. Nakamura, A. Ohashi, H. Harada, Appl. Environ. Microbiol. 65:1280-1288, 1999). Further 16S ribosomal DNA (rDNA) cloning-based analysis revealed that the microbes were classified within a unique clade, green non-sulfur bacteria (GNSB) subdivision I, which contains a number of 16S rDNA clone sequences from various environmental samples but no cultured representatives. To investigate their function in the community and physiological traits, we attempted to isolate the yet-to-be-cultured microbes from the original granular sludge. The first attempt at isolation from the granules was, however, not successful. In the other thermophilic reactor that had been treating fried soybean curd-manufacturing wastewater, we found filamentous microorganisms to outgrow, resulting in the formation of projection-like structures on the surface of granules, making the granules look like sea urchins. 16S rDNA-cloning analysis combined with fluorescent in situ hybridization revealed that the projections were comprised of the uncultured filamentous cells affiliated with the GNSB subdivision I and Methanothermobacter-like cells and the very ends of the projections were comprised solely of the filamentous cells. By using the tip of the projection as the inoculum for primary enrichment, a thermophilic, strictly anaerobic, filamentous bacterium, designated strain UNI-1, was successfully isolated with a medium supplemented with sucrose and yeast extract. The strain was a very slow growing bacterium which is capable of utilizing only a limited range of carbohydrates in the presence of yeast extract and produced hydrogen from these substrates. The growth was found to be significantly stimulated when the strain was

  18. Limitation of the Predominant-Period Estimator for Earthquake Early Warning and the Initial Rupture of Earthquakes

    Science.gov (United States)

    Yamada, T.; Ide, S.

    2007-12-01

    Earthquake early warning is an important and challenging issue for the reduction of the seismic damage, especially for the mitigation of human suffering. One of the most important problems in earthquake early warning systems is how immediately we can estimate the final size of an earthquake after we observe the ground motion. It is relevant to the problem whether the initial rupture of an earthquake has some information associated with its final size. Nakamura (1988) developed the Urgent Earthquake Detection and Alarm System (UrEDAS). It calculates the predominant period of the P wave (τp) and estimates the magnitude of an earthquake immediately after the P wave arrival from the value of τpmax, or the maximum value of τp. The similar approach has been adapted by other earthquake alarm systems (e.g., Allen and Kanamori (2003)). To investigate the characteristic of the parameter τp and the effect of the length of the time window (TW) in the τpmax calculation, we analyze the high-frequency recordings of earthquakes at very close distances in the Mponeng mine in South Africa. We find that values of τpmax have upper and lower limits. For larger earthquakes whose source durations are longer than TW, the values of τpmax have an upper limit which depends on TW. On the other hand, the values for smaller earthquakes have a lower limit which is proportional to the sampling interval. For intermediate earthquakes, the values of τpmax are close to their typical source durations. These two limits and the slope for intermediate earthquakes yield an artificial final size dependence of τpmax in a wide size range. The parameter τpmax is useful for detecting large earthquakes and broadcasting earthquake early warnings. However, its dependence on the final size of earthquakes does not suggest that the earthquake rupture is deterministic. This is because τpmax does not always have a direct relation to the physical quantities of an earthquake.

  19. Association of social support with gratitude and sense of coherence in Japanese young women: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Fujitani T

    2017-06-01

    Full Text Available Tomoko Fujitani,1 Kumiko Ohara,1 Katsuyasu Kouda,2 Tomoki Mase,3 Chiemi Miyawaki,4,5 Katsumasa Momoi,1,6 Yoshimitsu Okita,7 Maki Furutani,1 Harunobu Nakamura1 1Graduate School of Human Development and Environment, Kobe University, Kobe, 2Department of Public Health, Faculty of Medicine, Kindai University, Osaka-Sayama, 3Faculty of Human Development and Education, Kyoto Women’s University, 4Department of Early Childhood Education, Heian Jogakuin College, Kyoto, 5Kagoshima University Research Field in Education, Education, Law, Economics and the Humanities Area, Kagoshima, 6Faculty of Health and Welfare, Tokushima Bunri University, Tokushima, 7Graduate School of Integrated Science and Technology, College of Engineering, Academic Institute, Shizuoka University, Hamamatsu, Shizuoka, Japan Purpose: Recent studies have shown that perceived social support is associated with gratitude and sense of coherence, but evidence for this concept remains scarce. In the present study, we investigated relationships between social support, gratitude, and sense of coherence, focusing on the construct of and source of social support among young women. Methods: The study was conducted in 2014 in Japan. Participants comprised 208 female university students (aged 19.9 ± 1.1 years, who completed a self-administered anonymous questionnaire regarding perceived social support, gratitude, and sense of coherence. Results: Emotional and instrumental social support from acquaintances were found to be lower than those from family and friends. Gratitude was positively correlated with all forms of social support except instrumental social support from acquaintances. However, sense of coherence was positively correlated with both emotional and instrumental social support from family and only emotional social support from acquaintances. Multiple regression analysis showed that ­emotional support from family and emotional support from acquaintances were positively associated

  20. Theoretical study of ultraviolet induced photodissociation dynamics of sulfuric acid

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, Tatsuhiro; Ohta, Ayumi; Suzuki, Tomoya; Ikeda, Kumiko [Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-Cho, Chiyoda-ku, Tokyo 102-8554 (Japan); Danielache, Sebastian O. [Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-Cho, Chiyoda-ku, Tokyo 102-8554 (Japan); Earth-Life Science Institute (ELSI), Tokyo Institute of Technology (Japan); Department of Environmental Science and Techonology, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Yoohama 226-8502 (Japan); Nanbu, Shinkoh, E-mail: shinkoh.nanbu@sophia.ac.jp [Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-Cho, Chiyoda-ku, Tokyo 102-8554 (Japan)

    2015-05-01

    Highlights: • Photodissociation dynamics of H{sub 2}SO{sub 4} at low-lying electronically excited states were investigated. • Photochemical processes were simulated by on-the-fly ab initio MD. • Sulfuric acid after the excitation to the S{sub 1} state dissociated to HSO{sub 4}(1{sup 2}A″) + H({sup 2}S). • Sulfuric acid after the excitation to the S{sub 2} state dissociated to HSO{sub 4}(2{sup 2}A″) + H({sup 2}S). • The energy region of the UV spectra where NMD fractionation may occur is predicted. - Abstract: Photodissociation dynamics of sulfuric acid after excitation to the first and second excited states (S{sub 1} and S{sub 2}) were studied by an on-the-fly ab initio molecular dynamics simulations based on the Zhu–Nakamura version of the trajectory surface hopping (ZN-TSH). Forces acting on the nuclear motion were computed on-the-fly by CASSCF method with Dunning’s augmented cc-pVDZ basis set. It was newly found that the parent molecule dissociated into two reaction-channels (i) HSO{sub 4}(1{sup 2}A″) + H({sup 2}S) by S{sub 1}-excitation, and (ii) HSO{sub 4}(2{sup 2}A″) + H({sup 2}S) by S{sub 2}-excitation. The direct dissociation dynamics yield products different from the SO{sub 2} + 2OH fragments often presented in the literature. Both channels result in the same product and differs only in the electronic state of the HSO{sub 4} fragment{sub .} The trajectories running on S{sub 2} do not hop with S{sub 0} and a nonadiabatic transition happens at the S{sub 2}–S{sub 1} conical intersection located at a longer OH bond-length than the S{sub 1}–S{sub 0} intersection producing an electronic excited state (2{sup 2}A″) of HSO{sub 4} product.

  1. PREFACE: 14th International Conference on Micro and Nanotechnology for Power Generation and Energy Conversion Applications (PowerMEMS 2014)

    Science.gov (United States)

    2014-11-01

    create strong networks between researchers. We also provide nice opportunities to experience Japanese nature and culture. The special cruise to see the magnificent whirlpool up close will definitely be one of the highlights. Additionally, we will serve Awaji's traditional performing art, Awaji Ningyo Joruri, which has a history of over 500 years and has been inherited through the generations. There are many individuals we would like to thank for their support in organizing PowerMEMS2014. The TPC, chaired by Takayuki Fujita, have given us their valuable time and best effort in reviewing abstracts. The PowerMEMS School chair Yuji Suzuki and the expert speakers made the School possible. The local organizing committee, led by Kensuke Kanda has provided us with invaluable assistance in preparing the PowerMEMS2014 venue. The financial support from both the Tsutomu Nakauchi Foundation, the Hyogo International Association and the conference sponsors have also been gratefully appreciated. Finally, we would like to thank each of you for attending the conference and bringing your expertise. We wish you all a successful conference and an exciting and relaxing stay in Awaji Island.

  2. PREFACE: 7th International Conference on Applications of Physics in Financial Analysis

    Science.gov (United States)

    Takayasu, M.; Watanabe, T.; Ikeda, Y.; Takayasu, H.

    2010-04-01

    become interested in such datasets, conducting empirical investigations about various aspects of economic activities. Specifically, they have searched for regularities and 'laws' akin to the ones in natural science, successfully producing fascinating results, as shown in the papers contained in this volume. Each paper submitted for publication in this volume has gone through the refereeing process, and has been revised on the basis of comments and discussion at the conference as well as comments from the anonymous referees. Finally, 19 papers were accepted for publication. The editors are very grateful to the colleagues involved in the refereeing process for their rapid and careful reviewing of the papers. We thank Takayuki Mizuno, Koji Sakai, Hiwon Yoon and Hiroki Matsui for their support for the conference. We appreciate the administrative assistance provided by Yayoi Hatano of Hitotsubashi University, and Masahiko Ozaki, Masato Yamada and Tomoko Kase of RIETI. We are most grateful to the authors for their contributions, as well as to the participants, all of whom made this conference stimulating and enjoyable. Misako Takayasu Tokyo Institute of Technology, Japan Tsutomu Watanabe Hitotsubashi University, Japan RIETI, Japan Yuichi Ikeda Hitachi Research Laboratory, Hitachi Ltd, Japan Hideki Takayasu Sony Computer Science Laboratories, Inc, Japan

  3. LLE Review Quarterly Report July-September 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-12-01

    This volume of the LLE Review, covering July-September 2000, begins with an article by T. R. Boehly, V. N. Goncharov, O. Gotchev, J. P. Knauer, D. D. Meyerhofer, D. Oron, S. P. Regan, Y. Srebro, W. Seka, D. Shvarts, S. Skupsky, and V.A. Smalyuk, who describe measurements of the effect of beam smoothing and pulse shape on imprinting. (Imprinting is defined as the imposition of pressure perturbations on the target by spatial variations in the laser intensity.) A principal result is the observation of reduced levels of imprint with the higher beam smoothing afforded by 1-THz smoothing by spectral dispersion (SSD). Additional highlights of research presented in this issue are: (1) P. W. McKenty, V. N. Goncharov, R. P. J. Town, S. Skupsky, R. Betti, and R. L. McCrory describe calculations of directly driven ignition capsule performance on the National Ignition Facility (NIF). The authors detail how the various contributors to implosion disruption (laser imprint, power imbalance, and target roughness) affect target performance and final gain. The conclusions are obtained by examining the simulated target evolution with the two-dimensional hydrodynamics computer code ORCHID. (2) D. D. Meyerhofer, J. A. Delettrez, R. Epstein, V. Yu. Glebov, V. N. Goncharov, R. L. Keck, R. L. McCrory, P. W. McKenty, F. J. Marshall, P. B. Radha, S. P. Regan, S. Roberts, W. Seka, S. Skupsky, V. A. Smalyuk, C. Sorce, C. Stoeckl, J. M. Soures, R. P. J. Town, B. Yaakobi, J. D. Zuegel, J. Frenje, C. K. L1,R. D. Petrasso, F. Seguin, K. Fletcher, S. Padalino, C. Freeman, N. Izumi, R. Lerche, T. W. Phillips, and T. C. Sangster describe the results of a series of direct-drive implosions of gas-fusion-fuel-filled plastic shells performed on the OMEGA laser system. The experiments include those performed with 1-THZ SSD and high-quality power balance. (3) V. Yu. Glebov, D. D. Meyerhofer, C. Stoeckl, and J. D. Zuegel describe the technique of measuring secondary neutron yield (DT neutron yield from D

  4. PREFACE: Tenth International Conference on Topics in Astroparticle and Underground Physics (TAUP2007)

    Science.gov (United States)

    Inoue, Kunio; Suzuki, Atsuto; Mitsui, Tadao

    2008-07-01

    The tenth meeting of the TAUP Workshop Series, TAUP 2007, was organized by the Research Center for Neutrino Science, Tohoku University. In TAUP 2007 all the various aspects of Astroparticle Physics have been covered, from Cosmology and Dark Constituents, to Gravitational Waves, to Neutrino Physics and Astrophysics, to High Energy Astrophysics, to Cosmic Rays and Gamma-Rays Astronomy. New and important scientific results were presented and debated in the plenary review talks and in a very large number of contributions in topical parallel sessions. As editors of these proceedings, we hope that this volume, which contains most of the talks and contributions presented at TAUP 2007, will provide a detailed state-of-the-art account of the various facets of Astroparticle Physics. We thank all the invited speakers, conveners, and contributors who made this possible. Full coverage of the transparencies presented at the conference can be found on the website http://www.awa.tohoku.ac.jp/taup2007. The TAUP 2007 Organizing Committee thanks IUPAP/PaNAGIC, Sendai Tourism and Convention Bureau, COE program: Exploring New Science by Bridging Particle-Matter Hierarchy, SEIKO EG&G, and REPIC corporation for sponsoring the Conference, and Sendai Civic Auditorium, where the meeting was held, for their hospitality. We wish to thank Alessandro Bottino, Junpei Shirai, Fumihiko Suekane, David Sinclair, Takaaki Kajita, Takeo Moroi, Masaki Mori, Masahiro Kawasaki, Yoshihito Gando, Sei Yoshida, Kyoko Tamae, Sanshiro Enomoto, Alexandre Kozlov, Yasuhiro Kishimoto, Itaru Shimizu, Kengo Nakamura, Haruo Ikeda, and Kyo Nakajima for their invaluable contribution in the scientific shaping of the conference and in the preparation of the present volume. The Organizing Committee is grateful to the members of the International Advisory Committee and of the TAUP Steering Committee for assistance and advice on the scientific program. Very special thanks are due to Ms Rika Bizen, Mr Fujio Miura, Ms Akemi

  5. Impact of β-blocker selectivity on long-term outcomes in congestive heart failure patients with chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Kubota Y

    2015-03-01

    Full Text Available Yoshiaki Kubota, Kuniya Asai, Erito Furuse, Shunichi Nakamura, Koji Murai, Yayoi Tetsuou Tsukada, Wataru Shimizu Department of Medicine (Division of Cardiology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan Background: Chronic obstructive pulmonary disease (COPD is present in approximately one-third of all congestive heart failure (CHF patients, and is a key cause of underprescription and underdosing of β-blockers, largely owing to concerns about precipitating respiratory deterioration. For these reasons, the aim of this study was to evaluate the impact of β-blockers on the long-term outcomes in CHF patients with COPD. In addition, we compared the effects of two different β-blockers, carvedilol and bisoprolol. Methods: The study was a retrospective, non-randomized, single center trial. Acute decompensated HF patients with COPD were classified according to the oral drug used at discharge into β-blocker (n=86; carvedilol [n=52] or bisoprolol [n=34] and non-β-blocker groups (n=46. The primary endpoint was all-cause mortality between the β-blocker and non-β-blocker groups during a mean clinical follow-up of 33.9 months. The secondary endpoints were the differences in all-cause mortality and the hospitalization rates for CHF and/or COPD exacerbation between patients receiving carvedilol and bisoprolol. Results: The mortality rate was higher in patients without β-blockers compared with those taking β-blockers (log-rank P=0.039, and univariate analyses revealed that the use of β-blockers was the only factor significantly correlated with the mortality rate (hazard ratio: 0.41; 95% confidence interval: 0.17–0.99; P=0.047. Moreover, the rate of CHF and/or COPD exacerbation was higher in patients treated with carvedilol compared with bisoprolol (log-rank P=0.033. In the multivariate analysis, only a past history of COPD exacerbation significantly increased the risk of re-hospitalization due to CHF and/or COPD exacerbation (adjusted hazard

  6. Additive effects of cilnidipine, an L-/N-type calcium channel blocker, and an angiotensin II receptor blocker on reducing cardiorenal damage in Otsuka Long-Evans Tokushima Fatty rats with type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Mori Y

    2014-06-01

    Full Text Available Yutaka Mori,1,2 Shizuka Aritomi,3 Kazumi Niinuma,3 Tarou Nakamura,3 Kenichi Matsuura,1 Junichi Yokoyama,1 Kazunori Utsunomiya1 1Division of Diabetes and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine, Minato-ku, Japan; 2Department of Clinical Research, National Hospital Organization, Utsunomiya National Hospital, Utsunomiya, Japan; 3Research Center, Ajinomoto Pharmaceuticals Co, Ltd, Kanagawa, Japan Abstract: Cilnidipine (Cil, which is an L-/N-type calcium channel blocker (CCB, has been known to provide renal protection by decreasing the activity of the sympathetic nervous system (SNS and the renin–angiotensin system. In this study, we compared the effects of the combination of Cil and amlodipine (Aml, which is an L-type CCB, with an angiotensin (Ang II receptor blocker on diabetic cardiorenal damage in spontaneously type 2 diabetic rats. Seventeen-week-old Otsuka Long-Evans Tokushima Fatty rats were randomly assigned to receive Cil, Aml, valsartan (Val, Cil + Val, Aml + Val, or a vehicle (eight rats per group for 22 weeks. Antihypertensive potencies were nearly equal among the CCB monotherapy groups and the combination therapy groups. The lowering of blood pressure by either treatment did not significantly affect the glycemic variables. However, exacerbations of renal and heart failure were significantly suppressed in rats administered Cil or Val, and additional suppression was observed in those administered Cil + Val. Although Val increased the renin–Ang system, Aml + Val treatment resulted in additional increases in these parameters, while Cil + Val did not show such effects. Furthermore, Cil increased the ratio of Ang-(1–7 to Ang-I, despite the fact that Val and Aml + Val decreased the Ang-(1–7 levels. These actions of Cil + Val might be due to their synergistic inhibitory effect on the activity of the SNS, and on aldosterone secretion through N-type calcium channel antagonism and Ang II

  7. Estimation and Simulation of Inter-station Green's Functions in the Beppu-Bay Area, Oita Prefecture, Southwest Japan: the Effect of Sedimentary Basin

    Science.gov (United States)

    Hayashida, T.; Yoshimi, M.; Komatsu, M.; Takenaka, H.

    2017-12-01

    Continuous long-term observations of ambient noise (microseisms) were performed from August 2014 to February 2017 in the Beppu-Bay area, Oita prefecture, to investigate S-wave velocity structure of deep sedimentary basin (Hayashida et al., 2015SSJ; Yoshimi and Hayashida, 2017WCEE). The observation array consists of 12 broadband stations with an average spacing of 12 km. We applied the seismic interferometry technique to the ambient noise data and derived nine-component ambient noise cross-correlation functions (Z-R, Z-T, Z-Z, R-R, R-T, R-Z, T-R, T-T, and T-Z components) between 66 pairs of stations (distance of 6.4 km to 65.2 km). We assumed the stacked cross-correlation functions as "observed Green's functions" between two stations and estimated group velocities of Rayleigh and Love waves in the frequency between 0.2 and 0.5 Hz (Hayashida et al., 2017AGU-JpGU). Theoretical Green's functions for all stations pairs were also calculated using the finite difference method (HOT-FDM, Nakamura et al., 2012BSSA), with an existing three-dimensional basin structure model (J-SHIS V2) with land and seafloor topography and a seawater layer (Okunaka et al., 2016JpGU) and a newly constructed basin structure model of the target area (Yoshimi et al., 2017AGU). The comparisons between observed and simulated Green's functions generally show good agreements in the frequency range between 0.2 and 0.5 Hz. On the other hand, both observed and simulated Green's functions for some station pairs whose traverse lines run across the deeper part of the sedimentary basin (> 2000 m) show prominent later phases that might be generated and propagated inside the basin. This indicates that the understanding of the phase generation and propagation processes can be a key factor to validate the basin structure model and we investigated the characteristics of the later phases, such as its particle motions and arrival times, using observed and simulated Green's functions in detail. Acknowledgements

  8. Symptom predictors of response to electroconvulsive therapy in older patients with treatment-resistant depression

    Directory of Open Access Journals (Sweden)

    Tominaga K

    2011-07-01

    Full Text Available Keiichiro Tominaga¹, Mioto Okazaki¹, Hisashi Higuchi¹, Itaru Utagawa¹, Etsuko Nakamura², Noboru Yamaguchi¹¹Department of Neuropsychiatry, St Marianna University School of Medicine, Miyamae-ku, Kawasaki City, Kanagawa, ²Tsurukawa Sanatorium Hospital, Machida City, Tokyo, JapanBackground: Electroconvulsive therapy (ECT has been used for treatment-resistant depression. However, predictors of response to ECT have not been adequately studied using the Montgomery and Åsberg Depression Rating Scale, especially in older patients with treatment-resistant depression.Methods: This study included 18 Japanese patients who fulfilled the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition Text Revision criteria for a diagnosis of major depressive disorder or bipolar disorder with a current major depressive episode, and met the definition of treatment-resistant depression outlined by Thase and Rush, scoring ≥21 on the Montgomery and Åsberg Depression Rating Scale. The three-factor model of the Montgomery and Åsberg Depression Rating Scale was used for analysis. Factor 1 was defined by three items, factor 2 by four items, and factor 3 by three items, representing dysphoria, retardation, and vegetative symptoms, respectively. ECT was performed twice a week for a total of six sessions using a Thymatron System IV device with the brief pulse technique. Clinical responses were defined on the basis of a ≥50% decrease in total pretreatment Montgomery and Åsberg Depression Rating Scale scores.Results: The mean pretreatment factor 2 score for responders (n = 7 was significantly lower than that for nonresponders (n = 11. Furthermore, a significant difference in mean factor 3 score between responders and nonresponders was observed one week after six sessions of ECT, indicating a time lag of response. No significant differences were observed for age, number of previous episodes, and duration of the current episode between responders and

  9. Reef-scale modeling of coral calcification responses to ocean acidification and sea-level rise

    Science.gov (United States)

    Nakamura, Takashi; Nadaoka, Kazuo; Watanabe, Atsushi; Yamamoto, Takahiro; Miyajima, Toshihiro; Blanco, Ariel C.

    2018-03-01

    To predict coral responses to future environmental changes at the reef scale, the coral polyp model (Nakamura et al. in Coral Reefs 32:779-794, 2013), which reconstructs coral responses to ocean acidification, flow conditions and other factors, was incorporated into a reef-scale three-dimensional hydrodynamic-biogeochemical model. This coupled reef-scale model was compared to observations from the Shiraho fringing reef, Ishigaki Island, Japan, where the model accurately reconstructed spatiotemporal variation in reef hydrodynamic and geochemical parameters. The simulated coral calcification rate exhibited high spatial variation, with lower calcification rates in the nearshore and stagnant water areas due to isolation of the inner reef at low tide, and higher rates on the offshore side of the inner reef flat. When water is stagnant, bottom shear stress is low at night and thus oxygen diffusion rate from ambient water to the inside of the coral polyp limits respiration rate. Thus, calcification decreases because of the link between respiration and calcification. A scenario analysis was conducted using the reef-scale model with several pCO2 and sea-level conditions based on IPCC (Climate change 2013: the physical science basis. Contribution of working group I to the fifth assessment report of the intergovernmental panel on climate change, Cambridge University Press, Cambridge, 2013) scenarios. The simulation indicated that the coral calcification rate decreases with increasing pCO2. On the other hand, sea-level rise increases the calcification rate, particularly in the nearshore and the areas where water is stagnant at low tide under present conditions, as mass exchange, especially oxygen exchange at night, is enhanced between the corals and their ambient seawater due to the reduced stagnant period. When both pCO2 increase and sea-level rise occur concurrently, the calcification rate generally decreases due to the effects of ocean acidification. However, the

  10. Heterogeneous distribution of pelagic sediments incoming the Japan Trench possibly controlling slip propagation on shallow plate boundary fault

    Science.gov (United States)

    Yamaguchi, A.; Nakamura, Y.; Fukuchi, R.; Kurano, H.; Ikehara, K.; Kanamatsu, T.; Arai, K.; Usami, K.; Ashi, J.

    2017-12-01

    Catastrophic tsunami of the 2011 Tohoku Earthquake was triggered by large coseismic slip reached to the Japan Trench axis (e.g. Fujiwara et al., 2011, Science; Kodaira et al., 2012, Nature Geoscience). Results of the IODP Expedition 343 (JFAST) suggest that small friction of smectite-rich pelagic clay caused slip propagation on shallow plate boundary fault (Ujiie et al., 2013, Science; Kameda et al., 2015, Geology; Moore et al., 2015, Geosphere). On the other hand, JAMSTEC high-resolution seismic profiles show that incoming sediments have large heterogeneities in thicknesses, and two areas of extremely thin sediments on the Pacific Plate (thickness less than 100 m) were found at around 39°N (Nakamura et al., AGU 2017, this session). To reconcile whether the smectite-rich pelagic clay even exists in these areas, we sampled surface sediments during the R/V Shinsei Maru KS-15-3 cruise. Seven piston cores were retrieved from seaward trench slope, horst, graben, and graben edge. Core lithologies are mainly diatomaceous ooze/clay including tephra layers, not resemble to pelagic clays discovered in JFAST. Ages of tephra layers were estimated by correlating mineral assemblages and refractive indices of volcanic glasses to Japanese widespread tephras. Averaged sedimentation rates of seaward trench slope, horst, graben, and graben edge are estimated to be 25-30, 6.5-20, 45, 0.9 cm/kyr, respectively. These sedimentation rates imply that sediments on seaward trench slope and horst have been deposited in the last 160-500 kyr, suggesting that entire pelagic sediments, including smectite-rich pelagic clay, have been removed by some reasons in the last 0.5 million years. Possible reason for such modification of sediment is near-trench igneous activity known as petit-spot volcanism (Hirano et al., 2006, Science). The lack of smectite-rich pelagic clay near 39°N of the Japan Trench is consistent with results of tsunami inversions proposing shallow large coseismic slip propagated

  11. New approaches in geological studies of tsunami deposits

    Science.gov (United States)

    Szczucinski, Witold

    2017-04-01

    ., Nishimura Y., Kokociński M., Majewski W., Nakamura Y., Pawlowski J., 2016. Ancient sedimentary DNA reveals past tsunami deposits. Marine Geology 381: 29-33.

  12. Local Site Characterization Using HVSR, ReMi, and SPAC, Study Case: Soccer Field At Autonomous University of Santo Domingo, Dominican Republic

    Science.gov (United States)

    Upegui Botero, F. M.; Rojas Mercedes, N.; Huerta-Lopez, C.; Martinez-Cruzado, J. A.; Suárez, L.; Lopez, A. M.; Huerfano Moreno, V.

    2013-12-01

    Earthquake effects are frequently quantified by the energy liberated at the source, and the degree of damage produced in urban areas. The damage of historic events such as the Mw=8.3, September 19, 1985 Mexico City Earthquake was dominated by the amplification of seismic waves due to local site conditions. The assessment of local site effects can be carried out with site response analyses in order to determine the properties of the subsoil such as the dominant period, and the Vs30. The evaluation of the aforementioned properties is through the analysis of ground motion. However, in locations with low seismicity, the most convenient method to assess the site effect is the analysis of ambient vibration measurements. The Spatial Auto Correlation method (SPAC) can be used to determine a Vs30 model from ambient vibration measurements using a triangular array of sensors. Refraction Microtremor (ReMi) considers the phase velocity of the Rayleigh waves can be separated of apparent velocities; the aim of the ReMI method is to obtain the Vs30 model. The HVSR technique or Nakamura's method has been adopted to obtain the resonant frequency of the site from the calculation of ratio between the Fourier amplitude spectra or PSD spectrum of the horizontal and vertical components of ambient vibration. The aim of this work is to compare the results using different techniques to assess local site conditions in the urban area of Santo Domingo, Dominican Republic. The data used was collected during the Pan-American Advance Studies Institute (PASI), Workshop held in Santo Domingo, Dominican Republic from July 14 to 25, 2013. The PASI was sponsored by IRIS Consortium, NSF and DOE. Results obtained using SPAC, and ReMi, show a comparable model of surface waves velocities. In addition to the above, the HVSR method is combined with the stiffness matrices method for layered soils to calculate a model of velocities and the predominant period on the site. As part of this work a comparison with

  13. An in vivo mechanism for the reduced peripheral neurotoxicity of NK105: a paclitaxel-incorporating polymeric micellar nanoparticle formulation

    Directory of Open Access Journals (Sweden)

    Nakamura I

    2017-02-01

    Full Text Available Iwao Nakamura, Eiji Ichimura, Rika Goda, Hitomi Hayashi, Hiroko Mashiba, Daichi Nagai, Hirofumi Yokoyama, Takeshi Onda, Akira Masuda Nanomedicine Group, Pharmaceutical Research Laboratories, Nippon Kayaku Co., Ltd., Tokyo, Japan Abstract: In our previous rodent studies, the paclitaxel (PTX-incorporating polymeric micellar nanoparticle formulation NK105 had showed significantly stronger antitumor effects and reduced peripheral neurotoxicity than PTX dissolved in Cremophor® EL and ethanol (PTX/CRE. Thus, to elucidate the mechanisms underlying reduced peripheral neurotoxicity due to NK105, we performed pharmacokinetic analyses of NK105 and PTX/CRE in rats. Among neural tissues, the highest PTX concentrations were found in the dorsal root ganglion (DRG. Moreover, exposure of DRG to PTX (Cmax_PTX and AUC0-inf._PTX in the NK105 group was almost half that in the PTX/CRE group, whereas exposure of sciatic and sural nerves was greater in the NK105 group than in the PTX/CRE group. In histopathological analyses, damage to DRG and both peripheral nerves was less in the NK105 group than in the PTX/CRE group. The consistency of these pharmacokinetic and histopathological data suggests that high levels of PTX in the DRG play an important role in the induction of peripheral neurotoxicity, and reduced distribution of PTX to the DRG of NK105-treated rats limits the ensuing peripheral neurotoxicity. In further analyses of PTX distribution to the DRG, Evans blue (Eb was injected with BODIPY®-labeled NK105 into rats, and Eb fluorescence was observed only in the DRG. Following injection, most Eb dye bound to albumin particles of ~8 nm and had penetrated the DRG. In contrast, BODIPY®–NK105 particles of ~90 nm were not found in the DRG, suggesting differential penetration based on particle size. Because PTX also circulates as PTX–albumin particles of ~8 nm following injection of PTX/CRE, reduced peripheral neurotoxicity of NK105 may reflect exclusion from the

  14. Inhibitory effect of the Kampo medicinal formula Yokukansan on acute stress-induced defecation in rats

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    Kanada Y

    2018-04-01

    Full Text Available Yasuaki Kanada, Ayami Katayama, Hideshi Ikemoto, Kana Takahashi, Mana Tsukada, Akio Nakamura, Shogo Ishino, Tadashi Hisamitsu, Masataka Sunagawa Department of Physiology, School of Medicine, Showa University, Shinagawa-ku, Tokyo, Japan Objectives: Irritable bowel syndrome (IBS is a functional gastrointestinal disorder with symptoms of abnormal defecation and abdominal discomfort. Psychological factors are well known to be involved in onset and exacerbation of IBS. A few studies have reported effectiveness of traditional herbal (Kampo medicines in IBS treatment. Yokukansan (YKS has been shown to have anti-stress and anxiolytic effects. We investigated the effect of YKS on defecation induced by stress and involvement of oxytocin (OT, a peptide hormone produced by the hypothalamus, in order to elucidate the mechanism of YKS action. Methods and results: Male Wistar rats were divided into four groups; control, YKS (300 mg/kg PO-treated non-stress (YKS, acute stress (Stress, and YKS (300 mg/kg PO-treated acute stress (Stress+YKS groups. Rats in the Stress and Stress+YKS groups were exposed to a 15-min psychological stress procedure involving novel environmental stress. Levels of plasma OT in the YKS group were significantly higher compared with those in the Control group (P < 0.05, and OT levels in the Stress+YKS group were remarkably higher than those in the other groups (P < 0.01. Next, rats were divided into four groups; Stress, Stress+YKS, Atosiban (OT receptor antagonist; 1 mg/kg IP-treated Stress+YKS (Stress+YKS+B, and OT (0.04 mg/kg IP-treated acute stress (Stress+OT groups. Rats were exposed to acute stress as in the previous experiment, and defecation during the stress load was measured. Administration of YKS or OT significantly inhibited defecation; however, administration of Atosiban partially abolished the inhibitory effect of YKS. Finally, direct action of YKS on motility of isolated colon was assessed. YKS (1 mg/mL, 5 mg/mL did not

  15. Tabulation of comet observations.

    Science.gov (United States)

    1991-07-01

    Concerning comets: 1957 III Arend-Roland, 1957 V Mrkos, 1958 III Burnham, 1959 III Bester-Hoffmeister, 1959 VI Alcock, 1959 VIII P/Giacobini-Zinner, 1960 I P/Wild 1, 1960 II Burnham, 1960 III P/Schaumasse, 1960 VIII P/Finlay, 1961 V Wilson-Hubbard, 1961 VIII Seki, 1962 III Seki-Lines, 1962 VIII Humason, 1963 I Ikeya, 1963 III Alcock, 1963 V Pereyra, 1964 VI Tomita-Gerber-Honda, 1964 VIII Ikeya, 1964 IX Everhart, 1979 X Bradfield, 1980 X P/Stephan-Oterma, 1980 XII Meier, 1980 XIII P/Tuttle, 1981 II Panther, 1982 I Bowell, 1982 IV P/Grigg-Skjellerup, 1982 VII P/d'Arrest, 1986 III P/Halley, 1987 IV Shoemaker, 1987 XII P/Hartley 3, 1987 XIX P/Schwassmann-Wachmann 2, 1987 XXIX Bradfield, 1987 XXX Levy, 1987 XXXII McNaught, 1987 XXXIII P/Borrelly, 1987 XXXVI P/Parker-Hartley, 1987 XXXVII P/Helin- Roman-Alu 1, 1988 III Shoemaker-Holt, 1988 V Liller, 1988 VIII P/Ge-Wang, 1988 XI P/Shoemaker-Holt 2, 1988 XIV P/Tempel 2, 1988 XV Machholz, 1988 XX Yanaka, 1988 XXI Shoemaker, 1988 XXIV Yanaka, 1989 III Shoemaker, 1989 V Shoemaker-Holt-Rodriquez, 1989 VIII P/Pons-Winnecke, 1989 X P/Brorsen-Metcalf, 1989 XI P/Gunn, 1989 XIII P/Lovas 1, 1989 XVIII McKenzie-Russell, 1989 XIX Okazaki-Levy-Rudenko, 1989 XX P/Clark, 1989 XXI Helin-Ronan-Alu, 1989 XXII Aarseth-Brewington, 1989h P/Van Biesbroeck, 1989t P/Wild 2, 1989u P/Kearns-Kwee, 1989c1 Austin, 1989e1 Skorichenko-George, 1990a P/Wild 4, 1990b Černis-Kiuchi-Nakamura, 1990c Levy, 1990e P/Wolf-Harrington, 1990f P/Honda-Mrkos-Pajdušáková, 1990g McNaught-Hughes, 1990i Tsuchiya-Kiuchi, 1990n P/Taylor, 1990ο P/Shoemaker-Levy 1, 1991a P/Metcalf-Brewington, 1991b Arai, 1991c P/Swift-Gehrels, 1991d Shoemaker-Levy, 1991e P/Shoemaker-Levy 3, 1991h P/Takamizawa, 1991j P/Hartley 1, 1991k P/Mrkos, 1991l Helin-Lawrence, 1991n P/Faye, 1991q P/Levy, 1991t P/Hartley 2, P/Encke, P/Schwassmann-Wachmann 1.

  16. Difference of horizontal-to-vertical spectral ratios of observed earthquakes and microtremors and its application to S-wave velocity inversion based on the diffuse field concept

    Science.gov (United States)

    Kawase, Hiroshi; Mori, Yuta; Nagashima, Fumiaki

    2018-01-01

    We have been discussing the validity of using the horizontal-to-vertical spectral ratios (HVRs) as a substitute for S-wave amplifications after Nakamura first proposed the idea in 1989. So far a formula for HVRs had not been derived that fully utilized their physical characteristics until a recent proposal based on the diffuse field concept. There is another source of confusion that comes from the mixed use of HVRs from earthquake and microtremors, although their wave fields are hardly the same. In this study, we compared HVRs from observed microtremors (MHVR) and those from observed earthquake motions (EHVR) at one hundred K-NET and KiK-net stations. We found that MHVR and EHVR share similarities, especially until their first peak frequency, but have significant differences in the higher frequency range. This is because microtremors mainly consist of surface waves so that peaks associated with higher modes would not be prominent, while seismic motions mainly consist of upwardly propagating plain body waves so that higher mode resonances can be seen in high frequency. We defined here the spectral amplitude ratio between them as EMR and calculated their average. We categorize all the sites into five bins by their fundamental peak frequencies in MHVR. Once we obtained EMRs for five categories, we back-calculated EHVRs from MHVRs, which we call pseudo-EHVRs (pEHVR). We found that pEHVR is much closer to EHVR than MHVR. Then we use our inversion code to invert the one-dimensional S-wave velocity structures from EHVRs based on the diffuse field concept. We also applied the same code to pEHVRs and MHVRs for comparison. We found that pEHVRs yield velocity structures much closer to those by EHVRs than those by MHVRs. This is natural since what we have done up to here is circular except for the average operation in EMRs. Finally, we showed independent examples of data not used in the EMR calculation, where better ground structures were successfully identified from p

  17. Preface

    Science.gov (United States)

    Biefeld, Robert M.

    2017-04-01

    This special issue of the Journal of Crystal Growth collects some of the papers presented either orally or as posters at the 18th International Conference on Metalorganic Vapor Phase Epitaxy (ICMOVPE-XVIII) held at the Sheraton San Diego Hotel & Marina in San Diego, California, USA, from July 10 through July 15, 2016. This conference series was initiated in 1981 by the French in Ajaccio and is now held semi-annually with rotation between the USA, Asia, and Europe. The conference is pre-eminent in the field and the papers presented as well as those published in this volume represent the leading edge research in MOVPE done worldwide. This particular conference followed the earlier tradition in emphasizing semiconductor materials. The very successful program, which was organized by Andrew Allerman and Christine Wang, contained 219 papers which included 5 plenary speakers, the Harold M. Manasevit Young Investigator Award speech, 113 oral presentations, 6 rump session talks on future trends in industry, and 94 posters. The conference presentations were led off by Nobel Prize Winner Professor Shuji Nakamura talking about the invention of blue LEDs and the future of solid state lighting. There were ten session on III-nitride growth and devices, four sessions on nanostructures and their characterization, as well as sessions on photovoltaics, growth fundamentals, the growth of III-V's on Si and other materials. The conference brought together 255 participants from 26 countries including Australia, 1, Belgium, 3, Brazil, 1, Canada, 3, China, 11, Czech Republic, 5, Denmark, 2, France, 11, Germany, 41, Hong Kong, 3, India, 2, Ireland, 3, Italy, 1, Japan, 31, Netherlands, 1, Norway, 1, Poland, 2, Republic of Korea, 11, Russian Federation, 2, Saudi Arabia, 3, Spain, 3, Sweden, 2, Switzerland, 3, Taiwan, 12, the United Kingdom, 7, and the USA, 90. It is my pleasure to personally thank the Conference Organizing Committee, the MRS and the exhibitors and sponsors who helped to

  18. Cognitive impairment associated with locomotive syndrome in community-dwelling elderly women in Japan

    Directory of Open Access Journals (Sweden)

    Nakamura M

    2017-09-01

    Full Text Available Misa Nakamura,1 Fumie Tazaki,1 Kazuki Nomura,1 Taeko Takano,1 Masashi Hashimoto,1 Hiroshi Hashizume,2 Ichiro Kamei1 1Department of Rehabilitation, Osaka Kawasaki Rehabilitation University, Kaizuka, Osaka, Japan; 2Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan Abstract: In our worldwide aging society, elderly people should maintain cognitive and physical function to help avoid health problems. Dementia is a major brain disease among elderly people, and is caused by cognitive impairment. The locomotive syndrome (LS refers to a condition in which people require healthcare services because of problems associated with locomotion. The purpose of this study was to determine the association between cognitive impairment and LS. Study participants were 142 healthy elderly female volunteers living in a rural area in Japan. Cognitive function was assessed using the Mini-Mental State Examination (MMSE. A score of ≤26 points on the MMSE was used to indicate categorically defined poor cognitive performance (cognitive impairment. The LS was defined by a score ≥16 points, and non-LS as <16 points, on the 25-question Geriatric Locomotive Function Scale (GLFS-25. Twenty-one participants (14.8% had an MMSE score ≤26, and 19.0% were found to have LS. Compared with the MMSE >26 group, the ≤26 group was significantly older, had a higher percentage of body fat, and a higher GLFS-25 score. Those with LS were significantly older, had a higher body mass index, a higher percentage of body fat, and a lower MMSE score. Participants in the LS group had higher odds of cognitive impairment than those without LS [odds ratio (OR =3.08] by logistic regression analysis adjusted for age. Furthermore, participants with GLFS-25 scores ≥6 had higher odds of cognitive impairment than those with a GLFS-25 score <6 by logistic regression analysis adjusted for both age (OR =4.44, and age and percent body fat (OR =4.12. These findings

  19. PREFACE Surface Modifications of Diamond and Related Materials (Session D, E-MRS Spring Meeting)

    Science.gov (United States)

    Nebel, Christoph E.

    2010-11-01

    program in proposing invited speakers. Finally, our symposium would not have been successful without the strong involvement and implication of the EMRS headquarter especially P Siffert, T Lippert, S Schoeffter and C Kocher. They will all find here our sincere thanks. Christoph E Nebel (Chair) Fraunhofer-Institute for Applied Solid State Physics (IAF), Germany Takako Nakamura National Institute of Advanced Industrial Science and Technology (AIST), Japan Philippe Bergonzo CEA-LIST, France John Foord University of Oxford, United Kingdom Kian-Ping Loh National University of Singapore, Singapore

  20. Association Between a Wider Availability of Health Information and Health Care Utilization in Vietnam: Cross-Sectional Study.

    Science.gov (United States)

    Nguyen, Hoang Thuy Linh; Nakamura, Keiko; Seino, Kaoruko; Vo, Van Thang

    2017-12-18

    -related information can be used so that it will have a beneficial effect on care-seeking behavior should be a topic of concern to further health promotion in developing countries. ©Hoang Thuy Linh Nguyen, Keiko Nakamura, Kaoruko Seino, Van Thang Vo. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 18.12.2017.

  1. Evaluation of cone function by a handheld non-mydriatic flicker electroretinogram device

    Directory of Open Access Journals (Sweden)

    Nakamura N

    2016-06-01

    Full Text Available Natsuko Nakamura,1 Kaoru Fujinami,1 Yoshinobu Mizuno,2 Toru Noda,2 Kazushige Tsunoda11Laboratory of Visual Physiology, Division of Vision Research, National Institute of Sensory Organs, 2Department of Ophthalmology, National Hospital Organization, National Tokyo Medical Center, Tokyo, JapanPurpose: Full-field electroretinograms (ERGs are used to evaluate retinal function in patients with various types of hereditary and acquired retinal diseases. However, ERG recordings require relatively invasive procedures, including pupillary dilation and the use of contact lens electrodes. Thus, it would be helpful to have a simpler and noninvasive screening method. The purpose of this study was to determine whether a new, handheld, portable ERG device, RETeval™, can be used to screen patients for cone dysfunction.Patients and methods: Thirty-five eyes of 35 patients who had reduced cone responses ascertained by a conventional ERG system using contact lens electrodes were studied. The causative diseases included achromatopsia, cone dystrophy, cone-rod dystrophy, retinitis pigmentosa, choroidal dystrophy, autoimmune retinopathy, and Stargardt disease. The flicker ERGs were recorded with the RETeval™ under undilated conditions with skin electrodes (stimulus strength, 3.0 cd·s/m2; frequency, 28.3 Hz, and the responses were compared to that of 50 healthy eyes. The amplitudes and implicit times of the fundamental component of the flicker ERGs were analyzed in three age groups: Group A, ≤20 years; Group B, 21–40 years; and Group C, ≥41 years.Results: In all of the age groups, the amplitudes of the ERGs were significantly smaller and the implicit times significantly longer in patients with cone dysfunction than in the control eyes. All but one of the patients had flicker amplitudes lower than the mean −2.0 standard deviation of control eyes.Conclusion: The RETeval™ has a potential of being used to screen for cone dysfunction. The entire examination

  2. Significant correlations between optic nerve head microcirculation and visual field defects and nerve fiber layer loss in glaucoma patients with myopic glaucomatous disk

    Directory of Open Access Journals (Sweden)

    Yokoyama Y

    2011-12-01

    Full Text Available Yu Yokoyama, Naoko Aizawa, Naoki Chiba, Kazuko Omodaka, Masahiko Nakamura, Takaaki Otomo, Shunji Yokokura, Nobuo Fuse, Toru NakazawaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, JapanBackground: Eyes with glaucoma are characterized by optic neuropathy with visual field defects in the areas corresponding to the optic disk damage. The exact cause for the glaucomatous optic neuropathy has not been determined. Myopia has been shown to be a risk factor for glaucoma. The purpose of this study was to determine whether a significant correlation existed between the microcirculation of the optic disk and the visual field defects and the retinal nerve fiber layer thickness (RNFLT in glaucoma patients with myopic optic disks.Methods: Sixty eyes of 60 patients with myopic disks were studied; 36 eyes with glaucoma (men:women = 19:17 and 24 eyes with no ocular diseases (men:women = 14:10. The mean deviation (MD determined by the Humphrey field analyzer, and the peripapillary RNFLT determined by the Stratus-OCT were compared between the two groups. The ocular circulation was determined by laser speckle flowgraphy (LSFG, and the mean blur rate (MBR was compared between the two groups. The correlations between the RNFLT and MBR of the corresponding areas of the optic disk and between MD and MBR of the optic disk in the glaucoma group were determined by simple regression analyses.Results: The average MBR for the entire optic disk was significantly lower in the glaucoma group than that in the control group. The differences of the MBR for the tissue in the superior, inferior, and temporal quadrants of the optic disk between the two groups were significant. The MBR for the entire optic disk was significantly correlated with the MD (r = 0.58, P = 0.0002 and the average RNFLT (r = 0.53, P = 0.0008. The tissue MBR of the optic disk was significantly correlated with the RNFLT in the superior, inferior, and temporal quadrants

  3. Reproducibility of retinal circulation measurements obtained using laser speckle flowgraphy-NAVI in patients with glaucoma

    Directory of Open Access Journals (Sweden)

    Nakamura M

    2011-08-01

    Full Text Available Naoko Aizawa, Yu Yokoyama, Naoki Chiba, Kazuko Omodaka, Masayuki Yasuda, Takaaki Otomo, Masahiko Nakamura, Nobuo Fuse, Toru NakazawaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine Sendai, Miyagi, JapanBackground: Laser speckle flowgraphy (LSFG enables noninvasive quantification of the retinal circulation in glaucoma patients. In this study, we tested the intrasession reproducibility of LSFG-NAVI, a modified LSFG technique.Methods: Sixty-five eyes from 33 subjects (male (M:female (F = 17:16 with a mean age of 49.4 ± 11.2 years were examined in this study. Two parameters indicating reproducibility – the coefficient of variation (COV and the intraclass correlation coefficient (ICC – were analyzed three times on the same day that mean blur rate (MBR was measured using LSFG-NAVI. The sites analyzed were the retinal artery and vein, the optic disk, and the choroid. Following classification according to the Glaucoma Hemifield Test (GHT; SITA-Standard 30-2 program, the COV and ICC were examined in patients with (GHT+; 38 eyes, M:F = 20:18, average age 48.9 ± 12.8 years and without (GHT-; 27 eyes, M:F = 13:14, average age 50.1 ± 8.7 years abnormal glaucomatous visual fields.Results: For all subjects, the intrasession reproducibility of MBR in the optic disk (COV: 3.4 ± 2.0; ICC: 0.95 and choroid (COV: 4.7 ± 3.4; ICC: 0.98 was excellent. The reproducibility for the retinal vein (COV: 8.4 ± 5.6, ICC: 0.90 and retinal artery (COV: 10.9 ± 9.9, ICC: 0.9 was moderate. MBRs in the optic disk had good reproducibility in both the GHT+ group (COV: 3.8 ± 2.0; ICC: 0.97 and the GHT− group (COV: 2.9 ± 2.1; ICC: 0.95. Local assessment of the optic disk in normal or glaucoma patients showed that the COVs of the quadrant optic disk areas were best in the temporal area of MBR (3.4%, 4.2%, respectively.Conclusion: LSFG-NAVI showed favorable reproducibility in evaluation of retinal circulation of glaucoma patients, particularly in

  4. COMT Val158Met, but not BDNF Val66Met, is associated with white matter abnormalities of the temporal lobe in patients with first-episode, treatment-naïve major depressive disorder: a diffusion tensor imaging study

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    Hayashi K

    2014-06-01

    Full Text Available Kenji Hayashi,1 Reiji Yoshimura,1 Shingo Kakeda,2 Taro Kishi,3 Osamu Abe,4 Wakako Umene-Nakano,1 Asuka Katsuki,1 Hikaru Hori,1 Atsuko Ikenouchi-Sugita,1 Keita Watanabe,2 Satoru Ide,2 Issei Ueda,2 Junji Moriya,2 Nakao Iwata,3 Yukunori Korogi,2 Marek Kubicki,5 Jun Nakamura1 1Department of Psychiatry, 2Department of Radiology, University of Occupational and Environmental Health, Kitakyushu, Japan; 3Department of Psychiatry, Fujita Health University, Toyoake, Japan; 4Department of Radiology, Nihon University School of Medicine, Tokyo, Japan; 5Psychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA Abstract: We investigated the association between the Val158Met polymorphism of the catechol-O-methyltransferase (COMT gene, the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF gene, and white matter changes in patients with major depressive disorder (MDD and healthy subjects using diffusion tensor imaging (DTI. We studied 30 patients with MDD (17 males and 13 females, with mean age ± standard deviation [SD] =44±12 years and 30 sex- and age-matched healthy controls (17 males and 13 females, aged 44±13 years. Using DTI analysis with a tract-based spatial statistics (TBSS approach, we investigated the differences in fractional anisotropy, radial diffusivity, and axial diffusivity distribution among the three groups (patients with the COMT gene Val158Met, those with the BDNF gene Val66Met, and the healthy subjects. In a voxel-wise-based group comparison, we found significant decreases in fractional anisotropy and axial diffusivity within the temporal lobe white matter in the Met-carriers with MDD compared with the controls (P<0.05. No correlations in fractional anisotropy, axial diffusivity, or radial diffusivity were observed between the MDD patients and the controls, either among those with the BDNF Val/Val genotype or among the BDNF Met-carriers. These results suggest an association

  5. Combining biologic and phototherapy treatments for psoriasis: safety, efficacy, and patient acceptability

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    Farahnik B

    2016-07-01

    Full Text Available Benjamin Farahnik,1 Viraat Patel,2 Kourosh Beroukhim,3 Tian Hao Zhu,4 Michael Abrouk,2 Mio Nakamura,5 Rasnik Singh,3 Kristina Lee,5 Tina Bhutani,5 John Koo5 1University of Vermont College of Medicine, Burlington, VT; 2School of Medicine, University of California, Irvine, 3David Geffen School of Medicine, University of California, Los Angeles, 4University of Southern California Keck School of Medicine, Los Angeles, 5Department of Dermatology, Psoriasis and Skin Treatment Center, University of California, San Francisco, CA, USA Background: The efficacy and safety of biologic and phototherapy in treating moderate-to-severe psoriasis is well known. However, some patients may not respond well to biologic agents or phototherapy on their own and may require combination therapy. Skillfully combining a biologic agent and phototherapy may provide an additive improvement without much increase in risks.Objective: To summarize the current state of evidence for the efficacy and safety of combining biologics with phototherapy in the treatment of moderate-to-severe plaque psoriasis.Methods: We conducted an extensive search on Pubmed database for English language literature that evaluated the use of a combination of biologic and phototherapy for the treatment of moderate-to-severe psoriasis through January 2016. The search included the following keywords: psoriasis, etanercept, adalimumab, infliximab, ustekinumab, biologics, phototherapy, and combination therapy.Results: The primary literature included randomized controlled trials, a head-to-head study, open-label controlled and uncontrolled trials, case series, and case reports. Etanercept was used in over half of the reported cases, but other biologic agents used included ustekinumab, adalimumab, and infliximab. The vast majority of phototherapy was narrowband ultraviolet B (NBUVB radiation. Most cases reported enhanced improvement with combination therapy. Serious adverse events throughout the study duration

  6. Development of Strain-Induced Quantum Well Intermixing Technique on InGaP/InAlGaP Laser Structures and Demonstration of First Orange Laser Diode

    KAUST Repository

    Al-Jabr, Ahmad Ali

    2016-08-01

    Laser Diodes (LD) have numerous applications for industry, military, medicine and communications. The first visible LD was invented in 1962 by Nick Holonyak, emitted at 710 nm (red). In 1990s, Shuji Nakamura invented the blue and green Light Emitting Diodes (LED) and later LDs. The production of LDs emitting between 532- 632 nm has been severely lagging behind the rest of the visible spectrum. Yellow and orange LDs are still not accessible due to the lack of successfully grown material with high optical efficiency. AlGaInP is the quaternary compound semiconductor used to grow green to red LEDs and red LDs. At a material composition that is supposed to lase below 630 nm, the optical efficiency becomes low due to the oxygen-related defects associated with high Al content. The quantum well intermixing (QWI) is a post-growth process that is applied to laser structure to tune the wavelength of laser. Until now, there are limited reports on successful intermixing of InGaP/InAlGaP laser structures while maintaining the crystal quality. In this work, we introduced a novel intermixing process that utilizes the high strain induced by the dielectric film during annealing to initiate the intermixing. We deposited SiO2 capping by plasma-enhanced chemical vapor deposition (PECVD) onto the InGaP/InAlGaP laser structure emitting at 635 nm, and then annealed the structure up to 950 Celsius for different periods of time, resulting in an astonishing 100 nm blueshift. This blueshift allowed us to produce an unprecedented shorter wavelength orange lasers emitting at 608 nm. For low degree of intermixing, we have noticed an increase in the intensity of the photoluminescence (PL) signal. The improvement in the PL signal was translated to a reduction in threshold current. We implemented the technique on an LED structure with Al-rich QWs emitting at 590 nm. Significant increase in the PL intensity (20 folds) was observed. By analyzing the improved structure, we observed reduction in oxygen

  7. Mapping sediment thickness of Islamabad city using empirical relationships: Implications for seismic hazard assessment

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    Khan, Sarfraz; Khan, M. Asif

    2016-04-01

    Soft sediments make an important component of the subsurface lithology, especially in areas underlain by river/stream basins. Occupying a position directly above the bedrock up to the land surface, these soft sediments can range in thickness from few centimeters to hundreds of meters. They carry a special nuisance in seismic hazards, as they serve as a source of seismic amplification that may enhance the seismic shaking of many folds. Determination of the thickness of the soft sediments is therefore crucial in seismic hazard analysis. A number of studies in recent years have demonstrated that frequency and amplitude spectrum obtained from the noise measurements during the recording of natural seismicity can be used to obtain thickness of soft sediments covering the bedrock. Nakamura (1989) presented a technique to determine such spectrum using ratio of horizontal to vertical components of the Rayleigh waves. The present study is based on an extensive set of microtremor measurements carried out in the Islamabad city, Pakistan. Fundamental frequencies were obtained from weak motion sensors and Tromino Engy Plus instruments to show that the correlation is clearly valid for a wide range of sediment thickness. A simple formula was derived for the investigated area to determine directly the thickness of sediments from the main peaks in the H/ V spectrum for seismometer and Tromino data separately. A comparison is made between sediment thicknesses derived from empirical relations developed in this study with those given in literature to demonstrate a positive correlation. The correlation of instrumental resonant frequencies with calculated resonant frequencies (theoretical) suggests that the relation derived from the noise measurements mostly depends on the velocity depth function of the shear wave. The fundamental frequency of the main peak of spectral ratio of H/ V using the both instruments correlates well with the thickness of sediments at the site obtained from the

  8. Incidence of dizziness and vertigo in Japanese primary care clinic patients with lifestyle-related diseases: an observational study

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    Wada M

    2015-04-01

    Full Text Available Masaoki Wada,1,2 Taro Takeshima,1 Yosikazu Nakamura,3 Shoichiro Nagasaka,4 Toyomi Kamesaki,1 Hiroshi Oki,2 Eiji Kajii1 1Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University, Tochigi, Japan; 2Oki Clinic, Ibaraki, Japan; 3Department of Public Health, Jichi Medical University, Tochigi, Japan; 4Department of Internal Medicine, Division of Endocrinology and Metabolism, Jichi Medical University, Tochigi, Japan Objective: Dizziness and vertigo are highly prevalent symptoms among patients presenting at primary care clinics, and peripheral vestibular disorder (PVD is their most frequent cause. However, the incidence of PVD has not been well documented. This study aimed to investigate the incidence of dizziness, vertigo, and PVD among patients presenting at a primary care clinic. Design: This was an observational study. Setting and participants: Between November 2011 and March 2013, we observed 393 patients, all at least 20 years old, who had been treated for chronic diseases such as hypertension, dyslipidemia, and diabetes mellitus for at least 6 months at a primary clinic (Oki Clinic in Japan. Outcome: The main outcome of interest was new incidence of dizziness, vertigo, and PVD events. During the 1-year follow-up period, the otorhinolaryngologist diagnosed and reported new PVD events. Results: The mean age of the 393 participants at entry was 65.5 years. Of the study participants, 12.7%, 82.4%, and 92.6% had diabetes mellitus, hypertension, and dyslipidemia, respectively. We followed up all the participants (100%. During the 662.5 person-years of follow-up, 121 cases of dizziness or vertigo (dizziness/vertigo and 76 cases of PVD were observed. The incidence of dizziness/vertigo and PVD was 194.7 (95% confidence interval: 161.6–232.6 per 1,000 person-years and 115.7 (95% confidence interval: 92.2–142.6 per 1,000 person-years, respectively. There were 61 cases of acute peripheral vestibulopathy, 12 of

  9. Book Reviews

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    Gert J. Oostindie

    1987-04-01

    Full Text Available - M.M. van Bruinessen, Ann Kumar, The diary of a Javanese Muslim; Politics and the pesantren 1883-1886, Canberra: Australian National University, Faculty of Asian Studies Monographs, New Series No. 71, 1985. - J.G. de Casparis, John N. Miksic, Archaeological research on the ‘Forbidden Hill’ of Singapore: Excavations at Fort Canning, 1984, Singapore: National Museum, 1985. - Bernhard Dahm, Audrey R. Kahin, Regional dynamics of the Indonesian revolution; Unity from diversity, Honolulu: University of Hawaii Press, 1985. XI + 306 pp. - G.W.J. Drewes, Marcel Bonneff, Pérégrinations javanaises. Les Voyages de R.M.A. Purwalelana; Une vision de Java au XIXe siècle (c.1860-1875, Études insulindiennes/Archipel, 7, Éditions de la Maison des Sciences de l’Homme, Paris, 1986. 384 pp. - C. Fasseur, C.W. Watson, Kerinci. Two historical studies. Occasional paper no.3, University of Kent at Canterbury, 1984, X + 63 pp. - L.G.M. Jaquet, The Kenpeitai in Java and Sumatra; Selections form the authorised history of the Kenpietai by the national federation of Kenpeitai veterans associations. - Pieter ter Keurs, Erhard Schlesier, Me’udana, Südost-Neuguinea, Teil 2, Das soziale Leben, 1983. - Werner Kraus, Mitsuo Nakamura, The crescent arises over the Banyan tree, Yogyakarta: Gadjah Mada University Press, 1983. XI + 223 pp. - J.A. de Moor, Leon Salim, Prisoners of Kota Cane, (Translated and introduced by Audrey R. Kahin, Ithaca, New York: Cornell modern Indonesia project, translation series, no. 66, 1986, 112 pp. - Gert J. Oostindie, Cornelis Ch. Goslinga, The Dutch in the Caribbean and in the Guianas 1680-1791. Assen: Van Gorcum, 1985. xvi + 712 pp., ill. - Gert J. Oostindie, Cornelis Ch. Goslinga, The Dutch in the Caribbean and on the Wild coast 1580-1680. Assen: Van Gorcum, 1971. xvi + 647 pp., ills. - S.O. Robson, J. Joseph Errington, Language and social change in Java: Linguistic reflexes of modernization in a traditional royal polity, Athens, Ohio

  10. The relationship between pain severity and patient-reported outcomes among patients with chronic low back pain in Japan

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    Montgomery W

    2016-06-01

    Full Text Available William Montgomery,1 Jeffrey Vietri,2 Jing Shi,3 Kei Ogawa,4 Sawako Kariyasu,4 Levent Alev,4 Masaya Nakamura5 1Eli Lilly Australia Pty Ltd., Sydney, NSW, Australia; 2Health Outcomes Practice, Kantar Health, Horsham, PA, 3Health Outcomes Practice, Kantar Health, Princeton, NJ, USA; 4Eli Lilly Japan K.K., Kobe, Japan; 5Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan Objective: The aim of this study was to quantify the impact of pain severity on patient-reported outcomes among individuals diagnosed with chronic low back pain in Japan. Methods: Data were provided by the 2012 Japan National Health and Wellness Survey (N=29,997, a web-based survey of individuals in Japan aged ≥18 years. This analysis included respondents diagnosed with low back pain of ≥3-month duration. Measures included the revised Medical Outcomes Study 36-Item Short-Form Survey Instrument, the Patient Health Questionnaire-9, the Generalized Anxiety Disorder-7 scale, the Work Productivity and Activity Impairment: General Health questionnaire, and self-reported all-cause health care visits (6 months. Generalized linear models were used to assess the relationship between outcomes and severity of pain in the past week as reported on a numeric rating scale ranging from 0 (no pain to 10 (pain as bad as you can imagine, controlling for length of diagnosis, sociodemographics, and general health characteristics. Results: A total of 290 respondents were included in the analysis; mean age was 56 years, 41% were females, and 56% were employed. Pain severity was 3/10 for the first quartile, 5/10 for the median, and 7/10 for the third quartile of this sample. Increasing severity was associated with lower scores for mental and physical component summaries and Short-Form 6D health utility, higher depression (Patient Health Questionnaire-9 and anxiety (Generalized Anxiety Disorder-7 scores, greater absenteeism and presenteeism, greater activity impairment

  11. A rapid calculation system for tsunami propagation in Japan by using the AQUA-MT/CMT solutions

    Science.gov (United States)

    Nakamura, T.; Suzuki, W.; Yamamoto, N.; Kimura, H.; Takahashi, N.

    2017-12-01

    We developed a rapid calculation system of geodetic deformations and tsunami propagation in and around Japan. The system automatically conducts their forward calculations by using point source parameters estimated by the AQUA system (Matsumura et al., 2006), which analyze magnitude, hypocenter, and moment tensors for an event occurring in Japan in 3 minutes of the origin time at the earliest. An optimized calculation code developed by Nakamura and Baba (2016) is employed for the calculations on our computer server with 12 core processors of Intel Xeon 2.60 GHz. Assuming a homogeneous fault slip in the single fault plane as the source fault, the developed system calculates each geodetic deformation and tsunami propagation by numerically solving the 2D linear long-wave equations for the grid interval of 1 arc-min from two fault orientations simultaneously; i.e., one fault and its conjugate fault plane. Because fault models based on moment tensor analyses of event data are used, the system appropriately evaluate tsunami propagation even for unexpected events such as normal faulting in the subduction zone, which differs with the evaluation of tsunami arrivals and heights from a pre-calculated database by using fault models assuming typical types of faulting in anticipated source areas (e.g., Tatehata, 1998; Titov et al., 2005; Yamamoto et al., 2016). By the complete automation from event detection to output graphical figures, the calculation results can be available via e-mail and web site in 4 minutes of the origin time at the earliest. For moderate-sized events such as M5 to 6 events, the system helps us to rapidly investigate whether amplitudes of tsunamis at nearshore and offshore stations exceed a noise level or not, and easily identify actual tsunamis at the stations by comparing with obtained synthetic waveforms. In the case of using source models investigated from GNSS data, such evaluations may be difficult because of the low resolution of sources due to a low

  12. Insomnia in patients on hemodialysis for a short versus long duration

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    Tomita T

    2016-09-01

    Full Text Available Tetsu Tomita,1 Norio Yasui-Furukori,1 Masaki Oka,1 Takaaki Shimizu,2 Aya Nagashima,2 Kento Mitsuhashi,2 Hisao Saito,3 Kazuhiko Nakamura1 1Department of Neuropsychiatry, Graduate School of Medicine, 2School of Medicine, Hirosaki University, 3Department of Urology, Oyokyo Kidney Research Institute, Hirosaki, Japan Background: Many studies have investigated insomnia and the factors associated with this condition in hemodialysis (HD patients, although the influence of HD duration has not been thoroughly investigated. In the present study, we investigated the factors, especially the duration of HD, associated with insomnia in HD patients.Patients and methods: A total of 138 patients undergoing HD were recruited, and the Japanese version of the Pittsburgh Sleep Quality Index (PSQI was used to assess the quality of sleep. Subjects with a total PSQI score up to 4 and those with a score of at least 5 were identified as normal subjects and subjects with insomnia, respectively. Additionally, we assessed restless legs syndrome, depression using the Center for Epidemiologic Studies Depression Scale, and health-related quality of life (QOL using the Short Form 8 Health Survey. We divided the subjects into two groups according to the median HD duration.Results: The prevalence rate of insomnia was 54.3% among all the subjects. Twenty-one subjects (15.2% had depression, 26 (18.8% had restless legs syndrome, and 75 (54.3% had insomnia. The median HD duration was 4 years. The scores of components 1 and 4 of the PSQI, subjective sleep quality and habitual sleep efficiency, did not show a significant difference between the normal and insomnia groups. The score of component 7, daytime dysfunction, showed a significant difference between the short and long HD duration groups. In multiple regression analysis, the score of the Short Form 8 Health Survey showed a significant association with the PSQI score in the long HD duration group, but no variable showed a

  13. Reduction in Vegetable Intake Disparities With a Web-Based Nutrition Education Intervention Among Lower-Income Adults in Japan: Randomized Controlled Trial.

    Science.gov (United States)

    Nakamura, Saki; Inayama, Takayo; Harada, Kazuhiro; Arao, Takashi

    2017-11-24

    maintain and increase vegetable intake for other groups. Current Controlled Trials (UMIN-ICDR): UMIN000019376; https://upload.umin.ac.jp/cgi-open-bin/ icdr_e/ctr_view.cgi?recptno=R000022404 (Archived by WebCite at http://www.webcitation.org/6u9wihBZU). ©Saki Nakamura, Takayo Inayama, Kazuhiro Harada, Takashi Arao. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 24.11.2017.

  14. Boron isotope systematics during magma-carbonate interaction: an experimental study from Merapi (Indonesia) and Vesuvius (Italy)

    Science.gov (United States)

    Deegan, F. M.; Jolis, E. M.; Troll, V. R.; Freda, C.; Whitehouse, M.

    2011-12-01

    mass transfer in subduction zones, where B is frequently employed as a tracer of deep crustal recycling [8]. [1] Chadwick et al. (2007) J. Petrol. 48, 1793-1812. [2] Deegan et al. (2010) J. Petrol. 51, 1027-1051. [3] Freda et al. (2010) Bull. Volcanol. 73, 241-256. [4] Jolis et al. (2011) in prep. [5] Leeman & Sisson (1996) Rev. Min. 33, 645-707. [6] Ishikawa & Nakamura (1993) Earth Planet Sci. Lett. 117, 567-580. [7] Deegan et al. (2011) Geology Today 27, 63-64. [8] Rose et al. (2001) Science 293, 281-283.

  15. Geology, mineralization and geochemistry of the Aqkand Cu occurrence (north of Zanjan, Tarom-Hashtjin zone

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    Maryam Feyzi

    2017-02-01

    , fluorite and chlorite are present in the gangue minerals that represent vein-veinlet, breccia, vug infill, replacement, colloform, cockade, crustiform and plumose textures. Comparison of Chondrite normalized (Nakamura, 1974 REE patterns of Eocene fresh and barren andesitic basalt lavas, Oligocene rhyolitic-rhyodacitic lavas and the mineralized samples at Aqkand indicate that ore-forming fluids are probably related to Oligocene rhyolitic-rhyodacitic lavas. However, leaching of some elements from the host andesitic basalt lavas may have also been involved in mineralization. The geological, mineralogical, geochemical, textural and structural characteristics of the Aqkand occurrence reveals that copper mineralization at Aqkand is an example of epithermal base metal mineralization within the Tarom-Hashtjin zone. Acknowledgements The authors are grateful to the University of Zanjan Grant Commission for research funding. Mr. A.A. Atashnema is also appreciated for his help during the field work. Journal of Economic Geology reviewers and editor are also thanked for their constructive suggestions on alterations to the manuscript. References Davies, R.G., 1977. Geological map of Bandar-e-Anzali, scale 1:250,000. Geological Survey of Iran. Faridi, M. and Anvari, A., 2000. Geological map of Hashtjin, scale 1:100,000. Geological Survey of Iran. Hirayama, K., Samimi, M., Zahedi, M. and Hushmand-Zadeh, A., 1966. Geology of the Tarom District, Western Part (Zanjan area north-west Iran, Geological Survey of Iran, Tehran, Report 8, 31 pp. Nakamura, N., 1974. Determination of REE, Ba, Fe, Mg, Na and K in carbonaceous and ordinary Chondrites. Geochimica et Cosmochimica Acta, 38(5: 755–773.

  16. Petrography, Geochemistry and Petrogenesis of Volcanic Rocks, NW Ghonabad, Iran

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    Sedigheh Zirjanizadeh

    2016-07-01

    .6mmin size. Trachyte is characterized by trachytic texture. Ninety percent of the rock consists of sanidine. In trachytes, 3 to 5% hornblende ( 0.3 mm is replaced by carbonates. Rhyolites contain quartz, plagioclase, sanidine, and biotite phenocrysts in a microcrystalline to glassy groundmass. Rhyodacitehas phenocrysts, some glomerophyric, consisting of quartz, 2 to 3% (0.1-0.5 mm, plagioclase 7 to 10% (0.2- 0.8 mm, hornblende 5% and biotite 1%. Up to 15% of sanidineis altered to clay minerals. Crystal tuff and lithic-crystal tuff are distributed overa large area. Using the Zr/TiO2 and Nb/Y diagram of Winchester and Fold (1977, samples are designated as rhyolite, dacite and sub-alkaline basalt. In the Co vs. Th diagram of Hastie et al. (2007, samples plot in the shoshonitic and high calc-alkaline, rhyolite, dacite and andesite-basalt fields. The REE patterns and trace element contents of the volcanic samples show: (1 LREE/HREE enrichment ((La/Yb N = 0.3 to 15.27, (2 Low negative Eu anomaly (ave.Eu*/Eu=0.2-0.85, (3 depletion in Ba, Sr, K2O, Zr and Ti (Lower continental crust-normalized spider diagram from Taylor and McLennan, 1985 and Chondrite-normalized diagram from Nakamura, 1974. Rhyolites show the most extreme negative Eu anomaly (Eu/Eu* = 0.2-0.3 compared with 0.65–0.85 for volcanic elsewhere and also show considerably differences in the contents of Rb,Sr,K,Ti,Zr,Hf,Ce. These differences are related to greater magmatic differentiation or derivation from the other sources. The Sr and Nd isotopic ratios of these volcanic rocks are: 87Sr/86Sr = 0.70699 to 0.71014 and 143Nd/144Nd =0.512144 to 0.512539. Assuming an age of 60 Ma, the initial 87Sr/86Sr ratios vary from 0.70671 to 0.71066 and initial 143Nd/144Nd values vary from 0.512098 0.51249 (εNdi = -9.1 to 0.51249 (εNdi = -1.4.In the εNdi versus (87Sr/86Sri diagram, the samples plot in the field typical of magmas that are of crustal origin or, at least, that underwent important processes of crustal assimilation

  17. PREFACE: The 16th International Symposium on Boron, Borides and Related Materials (ISBB 2008)

    Science.gov (United States)

    Tanaka, Takaho

    2009-07-01

    supported by Tokyo University of Science, Suwa and foundations including, the Kajima Foundation, Foundation for Promotion of Material Science and Technology of Japan and Nippon Sheet Glass Foundation for Materials Science and Engineering, as well as companies including JFE Steel Corporation, Shincron Co, Ltd, Toyo Kohan Co, Ltd, Fukuda Metal Foil and Powder Co, Ltd, Japan New Metals Co, Ltd, H C Starck Ltd and Fritsch Japan Co, Ltd. Editors Chair Takaho Tanaka (National Institute for Materials Science, Japan) Vice chairs Koun Shirai (Osaka University, Japan) Kaoru Kimura (The University of Tokyo, Japan) Ken-ichi Takagi (Tokyo City University, Japan) Touetsu Shishido (Tohoku University, Japan) Shigeru Okada (Kokushikan University) Hideaki Itoh (Nagoya University,Japan) Katsumitsu Nakamura (Nihon University, Japan) Organizing committee of ISBB 2008 K Takagi Chairman (Tokyo City University) T Tanaka Program Committee Chairman (National Institute for Materials Science) K Kimura Secretary (The University of Tokyo) J Akimitsu (Aoyama University)K Shirai (Osaka University) H Itoh (Nagoya University)T Shishido (Tohoku University) K Nakamura (Nihon University)K Soga (Tokyo University of Science) K Nishiyama (Tokyo University of Science, Suwa)M Takeda (Nagaoka University of Technology) S Okada (Kokushikan University)Y Yamazaki (Toyo Kohan Co, Ltd) International Scientific Committee 0f ISBB (2008-2011) K Takagi Chairman (Japan) B Albert (Germany) J-F Halet (France) M Takeda (Japan) M Antadze (Georgia) H Hillebrecht (Germany) T Tanaka (Japan) J Bauer (France) W Jung (Germany) R Telle (Germany) I Boustani (Germany) K Kimura (Japan) M Trenary (USA) D Emin (USA) T Mori (Japan) O Tsagareishvili (Georgia) M Engler (Germany) P D Ownby (USA) H Werheit (Germany) N Frage (Israel) P Rogl (Austria) G Will (Germany) Yu Grin (Germany) S Shalamberidze (Georgia) O Yucel (Turkey) V N Gurin (Russia) N Shitsevalova (Ukraine) G Zhang (China)

  18. Plasma levels of 3-methoxy-4-hydroxyphenylglycol are associated with microstructural changes within the cerebellum in the early stage of first-episode schizophrenia: a longitudinal VBM study

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    Nishimura J

    2014-12-01

    Full Text Available Joji Nishimura,1 Shingo Kakeda,1 Osamu Abe,2 Reiji Yoshimura,3 Keita Watanabe,1 Naoki Goto,3 Hikaru Hori,3 Toru Sato,1 Hidemasa Takao,4 Hiroyuki Kabasawa,5 Jun Nakamura,3 Yukunori Korogi1 1Department of Radiology, University of Occupational and Environmental Health School of Medicine, Fukuoka, Japan; 2Department of Radiology, Graduate School of Medicine, Nihon University, Tokyo, Japan; 3Department of Psychiatry, University of Occupational and Environmental Health School of Medicine, Fukuoka, Japan; 4Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; 5MR Applied Science Laboratory Japan, GE Yokogawa Medical Systems, Hino-shi, Tokyo, Japan Abstract: The aims of this study are to determine how the interval changes of the brain structures in the early stage of first-episode schizophrenia relate to the interval changes in the clinical data, including the clinical symptoms of schizophrenia and catecholaminergic measures (plasma homovanillic acid [HVA] and 3-methoxy-4-hydroxyphenylglycol [MHPG]. Regional brain volumes and fractional anisotropy (FA/mean diffusivity (MD with diffusion tensor imaging (DTI were measured at baseline and 6-month follow-up in a 3T magnetic resonance imaging (MRI system in a cohort of 16 schizophrenic patients, who were in their first episode at the time of baseline MRI. At the time of baseline and follow-up MRI, all 16 patients underwent evaluations that included a psychopathological assessment (Positive and Negative Syndrome Scale [PANSS] and peripheral catecholaminergic measures (plasma MHPG or HVA. For interval changes between baseline and follow-up MRI data (morphological change, MD, and FA, the correlation/regression analysis was performed as a series of single regression correlations in Statistical Parametric Mapping 5, with the interval changes in PANSS or plasma HVA and MHPG as the covariates of interest. Positive and inverse correlations contrasts were created, and in this

  19. Survival significance of epidermal growth factor receptor tyrosine kinase inhibitors and current staging system for survival after recurrence in patients with completely resected lung adenocarcinoma

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    Saji H

    2017-08-01

    Full Text Available Hisashi Saji,1,2 Hiroki Sakai,1 Hiroyuki Kimura,1 Tomoyuki Miyazawa,1 Hideki Marushima,1 Haruhiko Nakamura1 1Department of Chest Surgery, St Marianna University School of Medicine, Miyamae-ku, Kawasaki, Kanagawa, Japan; 2Department of Thoracic Surgery, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan Objective: We previously reported that the staging system and epidermal growth factor receptor (EGFR mutation status are key factors for treatment strategy and predicting survival. However, the significance of these factors as predictors of overall survival (OS and postoperative recurrence survival (PRS has not been sufficiently elucidated. The objective here was to investigate EGFR mutation status and p-stage, which affect PRS and OS in patients with completely resected lung adenocarcinoma, using a different database.Patients and methods: We retrospectively reviewed 56 consecutive lung adenocarcinoma patients with disease recurrence in St. Marianna University Hospital between January 2010 and December 2014.Results: EGFR mutants (M were detected in 16/56 patients (29%. The patients with EGFR M had a better OS than those with EGFR wild-type (WT status (5-year survival: 50.3% vs 43.1, P=0.133. There was no significant difference in the 3-year recurrence-free survival rate between patients with M and WT (6.3% vs 7.7%, P=0.656, and the patients with EGFR M had a significantly better 3-year PRS than those with WT (77.4% vs 51.7%, P=0.033. The 3-year PRS rate for patients with M/pathologic stage (p-stage I–II (87.5% was better than that for patients with M/p-stage III (60.0%, WT/p-stage I–II (52.7%, and WT/p-stage III (43.8%. There was a significant difference between patients with M/p-stage I and WT/p-stage I–II or WT/p-stage III (P=0.021 and 0.030, respectively. During the study period, of the 16 patients with mutants, 12 patients (75% received EGFR-tyrosine kinase inhibitor (TKI therapy and among the 40 patients with WT, no patient received

  20. Treatment patterns, health care resource utilization, and costs in Japanese adults with attention-deficit hyperactivity disorder treated with atomoxetine

    Directory of Open Access Journals (Sweden)

    Imagawa H

    2018-02-01

    Full Text Available Hideyuki Imagawa,1 Saurabh P Nagar,2 William Montgomery,3 Tomomi Nakamura,1 Masayo Sato,1 Keith L Davis2 1Medical Development Unit Japan, Eli Lilly Japan K.K., Kobe, Japan; 2RTI Health Solutions, Research Triangle Park, NC, USA; 3Global Patient Outcomes and Real World Evidence, Eli Lilly Australia, NSW, Australia Objective: To describe the characteristics and medication treatment patterns of adult patients with attention-deficit/hyperactivity disorder (ADHD prescribed atomoxetine in Japan. Materials and methods: A retrospective analysis of insurance claims data was conducted using the Japan Medical Data Center database. Adults (≥18 years with ADHD who had ≥1 atomoxetine claim from January 1, 2013 to December 31, 2014, and ≥180 to ≤900 days of follow-up were included. First atomoxetine claim defined the index date. Patient characteristics included age, gender, and comorbid conditions. Treatment patterns assessed included rates of atomoxetine discontinuation, switching, persistence, adherence (assessed via the medication possession ratio, and use of concomitant medications. Results: A total of 457 adults met all the inclusion criteria. Mean (SD age was 32.7 (10.4 years, and 61.0% of patients were male. Nearly 72.0% of the patients had at least one comorbid mental health condition in the baseline period; depression (43.8% and insomnia (40.7% were the most common mental health comorbidities. Most common physical comorbidities were chronic obstructive pulmonary disease (14.4% and diabetes (12.9%. Non-ADHD-specific psychotropics were prescribed to 59.7% of patients during the baseline period and to 65.9% during the follow-up period; 6.6% were prescribed non-ADHD-specific psychotropics concomitantly with atomoxetine. Overall, 40.0% of adults discontinued atomoxetine during the entire follow-up period and 65.9% were persistent with atomoxetine therapy at 3 months post-index date. Mean (SD atomoxetine medication possession ratio was 0.57 (0

  1. Dense Ocean Floor Network for Earthquakes and Tsunamis; DONET/ DONET2, Part2 -Development and data application for the mega thrust earthquakes around the Nankai trough-

    Science.gov (United States)

    Kaneda, Y.; Kawaguchi, K.; Araki, E.; Matsumoto, H.; Nakamura, T.; Nakano, M.; Kamiya, S.; Ariyoshi, K.; Baba, T.; Ohori, M.; Hori, T.; Takahashi, N.; Kaneko, S.; Donet Research; Development Group

    2010-12-01

    Yoshiyuki Kaneda Katsuyoshi Kawaguchi*, Eiichiro Araki*, Shou Kaneko*, Hiroyuki Matsumoto*, Takeshi Nakamura*, Masaru Nakano*, Shinichirou Kamiya*, Keisuke Ariyoshi*, Toshitaka Baba*, Michihiro Ohori*, Narumi Takakahashi*, and Takane Hori** * Earthquake and Tsunami Research Project for Disaster Prevention, Leading Project , Japan Agency for Marine-Earth Science and Technology (JAMSTEC) **Institute for Research on Earth Evolution, Japan Agency for Marine-Earth Science and Technology (JAMSTEC) DONET (Dense Ocean Floor Network for Earthquakes and Tsunamis) is the real time monitoring system of the Tonankai seismogenic zones around the Nankai trough southwestern Japan. We were starting to develop DONET to perform real time monitoring of crustal activities over there and the advanced early warning system. DONET will provide important and useful data to understand the Nankai trough maga thrust earthquake seismogenic zones and to improve the accuracy of the earthquake recurrence cycle simulation. Details of DONET concept are as follows. 1) Redundancy, Extendable function and advanced maintenance system using the looped cable system, junction boxes and the ROV/AUV. DONET has 20 observatories and incorporated in a double land stations concept. Also, we are developed ROV for the 10km cable extensions and heavy weight operations. 2) Multi kinds of sensors to observe broad band phenomena such as long period tremors, very low frequency earthquakes and strong motions of mega thrust earthquakes over M8: Therefore, sensors such as a broadband seismometer, an accelerometer, a hydrophone, a precise pressure gauge, a differential pressure gauge and a thermometer are equipped with each observatory in DONET. 3) For speedy detections, evaluations and notifications of earthquakes and tsunamis: DONET system will be deployed around the Tonankai seismogenic zone. 4) Provide data of ocean floor crustal deformations derived from pressure sensors: Simultaneously, the development of data

  2. Proceedings of the 8th International Symposium on Foundations of Quantum Mechanics in the Light of New Technology

    Science.gov (United States)

    Ishioka, Sachio; Fujikawa, Kazuo

    2006-06-01

    Preface -- Committees -- Opening address / H. Fukuyama -- Welcoming address / N. Osakabe -- Special lecture. Albert Einstein: opportunity and perception / C. N. Yang -- Quantum information and entanglement. Quantum optics with single atoms and photons / H. J. Kimble. Quantum information system experiments using a single photon source / Y. Yamamoto. Quantum communication and quantum computation with entangled photons / A. Zeilinger. High-fidelity quantum teleportation and a quantum teleportation network for continuous variables / N. Takei, A. Furusawa. Long lived entangled states / H. Häffner ... [et al.]. Quantum non-locality using tripartite entanglement with non-orthogonal states / J. V. Corbett, D. Home. Quantum entanglement and wedge product / H Heydari. Analysis of the generation of photon pairs in periodically poled lithium niobate / J. Söderholm ... [et al.]. Generation of entangled photons in a semiconductor and violation of Bell's inequality / G. Oohata, R. Shimizu, K. Edamatsu -- Quantum computing. Decoherence of a Josephson junction flux qubit / Y. Nakamura ... [et al.]. Spectroscopic analysis of a candidate two-qubit silicon quantum computer in the microwave regime / J. Gorman, D. G. Hasko, D. A. Williams. Berry phase detection in charge-coupled flux-qubits and the effect of decoherence / H. Nakano ... [et al.]. Locally observable conditions for the successful implementation of entangling multi-qubit quantum gates / H. F. Hofmann, R. Okamoto, S. Takeuchi. State control in flux qubit circuits: manipulating optical selection rules of microwave-assisted transitions in three-level artificial atoms / Y.-X. Liu ... [et al.]. The effect of local structure and non-uniformity on decoherence-free states of charge qubits / T. Tanamoto, S. Fujita. Entanglement-assisted estimation of quantum channels / A. Fujiwara. Superconducting quantum bit with ferromagnetic [symbol]-Junction / T. Yamashita, S. Takahashi, S. Maekawa. Generation of macroscopic Greenberger

  3. Management of radioactive materials and wastes: status, stakes and perspectives

    International Nuclear Information System (INIS)

    Champion, Didier; Devin, Patrick; Tanguy, Loic; Bernard, Herve; Minon, Jean-Paul; Leclaire, Arnaud; Gilli, Ludivine; Lheureux, Yves; Pescatore, Claudio; Barbey, Pierre; Schneider, Thierry; Gay, Didier; Forest, Isabelle; Hemidy, Pierre-Yves; Baglan, Nicolas; Desnoyers, Bruno; Pieraccini, Michel; Poncet, Philippe; Seguin, Bertille; Calvez, Marianne; Leclerc, Elisabeth; Bancelin, Estelle; Fillion, Eric; Segura, Yannick; Vernaz, Etienne; Granier, Guy; De Preter, Peter; Petitfrere, Michael; Laye, Frederic; Nakamura, Takashi; Gin, Stephane; Lebaron-Jacobs, Laurence; Dinant, Sophie; Vacquier, Blandine; Crochon, Philippe; Griffault, Lise; Smith, Graham

    2013-10-01

    studies - Safety and continuous improvements (Estelle BANCELIN - EDF, Eric FILLION - CEA); - Comparative analysis between a very-low level waste storage facility and a conventional waste storage facility (Yannick SEGURA - ANDRA); - Research on nuclear wastes (Etienne VERNAZ - CEA); - Wastes characterization and intercomparison exercise (Guy GRANIER - CETAMA); - Belgium situation with respect to the long-term management of radioactive wastes (Peter DE PRETER - ONDRAF); - Wastes management in post-accident situation - the CODIRPA works (Frederic LAYE - ASN); - Wastes management in contaminated areas: Japanese situation and experience feedback 2 years after the Fukushima accident (Takashi NAKAMURA - JANUS); Radioactive waste management in the USA (Stephane GIN - CEA) - Monitoring and environmental impact of radioactive waste storage sites (Sophie DINANT - ANDRA); - Lessons learnt from a mortality and cancer impact study in the vicinity of the Aube storage facility (Blandine VACQUIER - InVS); - Evaluation of dosimetric impacts of uranium mine tailings using modeling and comparison with environmental monitoring results (Philippe CROCHON - AREVA); - Cigeo's long-term impact - methodology and presentation of the biosphere approach (Lise GRIFFAULT - ANDRA); - Evaluation of long-term impacts of radioactive waste storage facilities - Lessons learnt and perspectives of the BIOPROTA program (Graham SMITH - GMS Abingdon Ltd)

  4. Boron diffusion in strained and strain-relaxed SiGe

    International Nuclear Information System (INIS)

    Wang, C.C.; Sheu, Y.M.; Liu, Sally; Duffy, R.; Heringa, A.; Cowern, N.E.B.; Griffin, P.B.

    2005-01-01

    SiGe has been utilized for aggressive CMOS technologies development recently and there are many references [M. Shima, T. Ueno, T. Kumise, H. Shido, Y. Sakuma, S. Nakamura, Symposium on VLSI Technology Technical Digest, 2002, pp. 94-95; T. Ghani, M. Armstrong, C. Auth, M. Bost, P. Charvat, G. Glass, T. Hoffmann, K. Johnson, C. Kenyon, J. Klaus, B. McIntyre, K. Mistry, A. Murthy, J. Sandford, M. Silberstein, S. Sivakumar, P. Smith, K. Zawadzki, S. Thompson, M. Bohr, International Electron Devices Meeting Technical Digest, December 2003, pp. 978-980; P. Bai, C. Auth, S. Balakrishnan, M. Bost, R. Brain, V. Chikarmane, R. Heussner, M. Hussein, J. Hwang, D. Ingerly, R. James, J. Jeong, C. Kenyon, E. Lee, S. Lee, N. Lindert, M. Liu, Z. Ma, T. Marieb, A. Murthy, R. Nagisetty, S. Natarajan, J. Neirynck, A. Ott, C. Parker, J. Sebastian, R. Shaheed, S. Sivakumar, J. Steigerwald, S. Tyagi, C. Weber, B. Woolery, A. Yeoh, K. Zhang, M. Bohr, International Electron Devices Meeting Technical Digest, December 2004, pp. 657-660] presenting the advantages brought by it. A better understanding regarding the boron diffusion behavior within and in the vicinity of SiGe is necessary to optimize the extension and the source/drain in pMOSFET. In order to achieve the goal, both effects from mechanical strain and Ge doping on boron diffusion have been investigated. However, only a few publications discuss the impacts of both. Furthermore, most researches investigate these two effects under the conditions of low boron concentration [P. Kuo, J.L. Hoyt, J.F. Gibbons, J.E. Turner, D. Lefforge, Appl. Phys. Lett. 66 (January (5)) (1995) 580-582; N.R. Zangenberg, J. Fage-Pedersen, J. Lundsgaard Hansen, A. Nylandsted Larsen, J. Appl. Phys. 94 (September (6)) (2003) 3883-3890] and high thermal budget anneal [P. Kuo, J.L. Hoyt, J.F. Gibbons, J.E. Turner, D. Lefforge, Appl. Phys. Lett. 66 (January (5)) (1995) 580-582; N.R. Zangenberg, J. Fage-Pedersen, J. Lundsgaard Hansen, A. Nylandsted Larsen, J. Appl

  5. Frequency-dependent spatiotemporal profiles of visual responses recorded with subdural ECoG electrodes in awake monkeys: Differences between high- and low-frequency activity.

    Science.gov (United States)

    Takaura, Kana; Tsuchiya, Naotsugu; Fujii, Naotaka

    2016-01-01

    preferred the peripheral visual fields with larger RFs. This suggests that neurons in TEO/TE first receive less selective spatial information via beta and low-gamma BLP but later receive more fine-tuned spatial foveal information via high-gamma power. This result is consistent with a hypothesis previously proposed by Nakamura et al. (1993) that states that visual processing in TEO/TE starts with coarse-grained information, which primes subsequent fine-grained information. Collectively, our results demonstrate that ECoG can be a potent tool for investigating the nature of the neural computations in each cortical region that cannot be fully understood by measuring only the spiking activity, through the incorporation of the knowledge of the spatiotemporal characteristics across all frequency bands. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  6. Immunization of rabbits with synthetic peptides derived from a highly conserved β-sheet epitope region underneath the receptor binding site of influenza A virus

    Directory of Open Access Journals (Sweden)

    Ideno S

    2013-11-01

    Full Text Available Shoji Ideno,1,3 Kaoru Sakai,1 Mikihiro Yunoki,2–4 Ritsuko Kubota-Koketsu,3,5 Yuji Inoue,3 Shota Nakamura,6 Teruo Yasunaga,6 Yoshinobu Okuno,5 Kazuyoshi Ikuta3 1Infectious Pathogen Research Section, Central Research Laboratory, Research and Development Division, Japan Blood Products Organization, Kobe, Japan; 2Research and Development Promotion Section, Research and Development Division, Japan Blood Products Organization, Tokyo, Japan; 3Department of Virology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan; 4Department of Veterinary Microbiology, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan; 5Kanonji Institute, The Research Foundation for Microbial Diseases of Osaka University, Kanonji, Kagawa, Japan; 6Department of Genome Informatics, Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan Background: There is increasing concern about the speed with which health care providers can administer prophylaxis and treatment in an influenza pandemic. Generally, it takes several months to manufacture an influenza vaccine by propagation of the virus in chicken eggs or cultured cells. Newer, faster protocols for the production of vaccines that induce broad-spectrum immunity are therefore highly desirable. We previously developed human monoclonal antibody B-1 that shows broadly neutralizing activity against influenza A virus H3N2. B-1 recognizes an epitope region that includes an antiparallel β-sheet structure underneath the receptor binding site of influenza hemagglutinin (HA. In this study, the efficacy of a synthetic peptide vaccine derived from this epitope region against influenza A was evaluated. Materials and methods: Two peptides were synthesized, the upper and lower peptides. These peptides comprise amino acid residues 167–187 and 225–241, respectively, of the B-1 epitope region of HA, which is involved in

  7. Multi-point observations of large-amplitude electric fields during substorms obtained by THEMIS

    Science.gov (United States)

    Ogasawara, K.; Kasaba, Y.; Nishimura, Y.; Hori, T.; Takada, T.; Miyashita, Y.; Angelopoulos, V.; Bonnell, J. W.; McFadden, J. P.

    2009-12-01

    Large-amplitude electric fields over 100 mV/m have been observed around the equatorial magnetosphere. These electric fields may contribute to energy transport and particle acceleration in the magnetosphere [e.g., Wygant et al., 2000, 2002], and seem to be related to fast plasma flows with a size of a few Re [Nakamura et al., 2001]. In order to understand their macroscopic characteristics and the effects to magnetic activities, it is important to observe both fields and particles simultaneously at multiple locations within several Re. Five THEMIS probes can frequently provide such chances. In this paper, we show the several events with large-amplitude electric fields during substorms obtained by THEMIS. One of the events is found in 05:50-06:00 UT on 11 March 2008, when TH-D (Xsm=-10.7 Re, Ysm=4.8 Re) and TH-E (Xsm=-10.3 Re, Ysm=5.6 Re) observed intense electric fields. At 05:54 UT, THEMIS GBO-s clearly showed the auroral onset signature. The great intensification was near the SNKQ station, and this structure moved westward with the speed of ~6 km/s. It corresponds to ~200 km/s, as mapped to the TH-D/E location. The footprints of TH-A (Xsm=-6.8 Re, Ysm=-0.4 Re), D, and E were close to the site of the aurora. The location of TH-D was beside that of TH-E, and TH-A was located earthward and eastward from the former two. The enhanced electric fields observed by TH-D and E were associated with magnetic dipolarization and earthward high-speed plasma flow. They were also associated with the depletion of electron density estimated by the spacecraft potential. These features are consistent with the model of plasma bubbles [e.g., Pontius and Wolf, 1990]. The Y components of plasma flows were 200-300 km/s, roughly consistent with the westward auroral motion as mapped to the equatorial magnetosphere. Also, we found that Poynting flux of low frequency was efficient to illuminate the auroral emissions. This fact suggests that electromagnetic energy is transported to the

  8. Significant improvement of bone mineral density by denosumab treatment in Japanese osteoporotic patients following breast cancer treatment

    Directory of Open Access Journals (Sweden)

    Nakamura Y

    2018-03-01

    Full Text Available Yukio Nakamura,1,2 Mikio Kamimura,3 Akio Morikawa,4 Akira Taguchi,5 Takako Suzuki,1 Hiroyuki Kato1 1Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, 2Department of Orthopedic Surgery, Showa-Inan General Hospital, Komagane, 3Center for Osteoporosis and Spinal Disorders, Kamimura Orthopaedic Clinic, Matsumoto, 4Department of Surgery, Showa-Inan General Hospital, Komagane, 5Department of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, Shiojiri, Japan Background: The aim of this study was to evaluate the effects of denosumab in patients with osteoporosis (OP and non-metastatic breast cancer following treatment of 1 surgery, 2 surgery and aromatase inhibitors, and 3 surgery, aromatase inhibitors, and anti-cancer agents, compared with those in primary OP patients. Patients and methods: In this retrospective 24-month study, patients were divided into the primary OP group (34 cases or OP receiving breast cancer treatment group (breast cancer group; 17 cases. We measured serum calcium, whole parathyroid hormone (PTH, 1,25OH2D3, bone alkaline phosphatase (BAP, tartrate-resistant acid phosphatase-5b (TRACP-5b, and bone mineral density (BMD of the lumbar 1–4 vertebrae (L-BMD and bilateral total hips (H-BMD for 24 months. Results: The percent changes of serum calcium in the breast cancer group were significantly lower than those in the primary OP group at 1 week, 1 and 12 months. The percent changes of whole PTH in the primary OP group were significantly lower than those in the breast cancer group at 2 and 4 months. Significant differences were found between the groups at 18 months (-34.5% in the primary OP group and -52.6% in the breast cancer group, respectively for the percent changes of BAP. Significant differences were found between the groups at 12, 18, and 24 months (-39.7% in the primary OP group and -64.0% in the breast cancer group at 24 months, respectively for the percent

  9. High-Efficiency Nitride-Based Solid-State Lighting. Final Technical Progress Report

    International Nuclear Information System (INIS)

    Paul T. Fini; Shuji Nakamura

    2005-01-01

    In this final technical progress report we summarize research accomplished during Department of Energy contract DE-FC26-01NT41203, entitled ''High-Efficiency Nitride-Based Solid-State Lighting''. Two teams, from the University of California at Santa Barbara (Principle Investigator: Dr. Shuji Nakamura) and the Lighting Research Center at Rensselaer Polytechnic Institute (led by Dr. N. Narendran), pursued the goals of this contract from thin film growth, characterization, and packaging/luminaire design standpoints. The UCSB team initially pursued the development of blue gallium nitride (GaN)-based vertical-cavity surface-emitting lasers, as well as ultraviolet GaN-based light emitting diodes (LEDs). In Year 2, the emphasis shifted to resonant-cavity light emitting diodes, also known as micro-cavity LEDs when extremely thin device cavities are fabricated. These devices have very directional emission and higher light extraction efficiency than conventional LEDs. Via the optimization of thin-film growth and refinement of device processing, we decreased the total cavity thickness to less than 1 (micro)m, such that micro-cavity effects were clearly observed and a light extraction efficiency of over 10% was reached. We also began the development of photonic crystals for increased light extraction, in particular for so-called ''guided modes'' which would otherwise propagate laterally in the device and be re-absorbed. Finally, we pursued the growth of smooth, high-quality nonpolar a-plane and m-plane GaN films, as well as blue light emitting diodes on these novel films. Initial nonpolar LEDs showed the expected behavior of negligible peak wavelength shift with increasing drive current. M-plane LEDs in particular show promise, as unpackaged devices had unsaturated optical output power of ∼ 3 mW at 200 mA drive current. The LRC's tasks were aimed at developing the subcomponents necessary for packaging UCSB's light emitting diodes, and packaging them to produce a white light

  10. Investigation of the association between the GLC3A locus and normal tension glaucoma in Japanese patients by microsatellite analysis

    Directory of Open Access Journals (Sweden)

    M Kamio

    2009-01-01

    Full Text Available M Kamio1*, A Meguro1*, M Ota2, N Nomura1, K Kashiwagi3, F Mabuchi3, H Iijima3, K Kawase4, T Yamamoto4, M Nakamura5, A Negi5, T Sagara6, T Nishida6, M Inatani7, H Tanihara7, M Aihara8, M Araie8, T Fukuchi9, H Abe9, T Higashide10, K Sugiyama10, T Kanamoto11, Y Kiuchi11, A Iwase12, S Ohno13, H Inoko14, N Mizuki11Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan; 2Department of Legal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan; 3Department of Ophthalmology, University of Yamanashi, Faculty of Medicine, Yamanashi, Japan; 4Department of Ophthalmology, Gifu University Graduate School of Medicine, Gifu, Japan; 5Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; 6Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan; 7Department of Ophthalmology and Visual Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan; 8Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan; 9Division of Ophthalmology and Visual Science, Graduated School of Medical and Dental Sciences, Niigata University, Niigata, Japan; 10Department of Ophthalmology and Visual Science, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan; 11Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan; 12Department of Ophthalmology, Tajimi Municipal Hospital, Tajimi, Gifu, Japan; 13Department of Ophthalmology, Hokkaido University School of Medicine, Sapporo, Japan; 14Department of Genetic Information, Division of Molecular Life Science, Tokai University School of Medicine, Isehara, Kanagawa, Japan; *These authors contributed equally to this reportPurpose: To investigate whether the GLC3A locus harboring the CYP1B1 gene is associated with normal tension glaucoma

  11. Examination of the site amplification factor of OBS and their application to magnitude estimation and ground-motion prediction for EEW

    Science.gov (United States)

    Hayashimoto, N.; Hoshiba, M.

    2013-12-01

    1. Introduction Ocean bottom seismograph (OBS) is useful for making Earthquake Early Warning (EEW) earlier. However, careful handling of these data is required because the installation environment of OBSs may be different from that of land stations. Site amplification factor is an important factor to estimate the magnitudes, and to predict ground motions (e.g. seismic intensity) in EEW. In this presentation, we discuss the site amplification factor of OBS in the Tonankai area of Japan from these two points of view. 2. Examination of magnitude correction of OBS In the EEW of JMA, the magnitude is estimated from the maximum amplitude of the displacement in real time. To provide the fast magnitude estimation, the magnitude-estimation algorithm switches from the P to S formula (Meew(P) to Meew(S)) depending on the expected S-phase arrival (Kamigaichi,2004). To estimate the magnitude correction for OBS, we determine Meew(P) and Meew(S) at OBSs and compare them with JMA magnitude (Mjma). We find Meew(S) at OBS is generally larger than Mjma by approximately 0.6. The slight differences of spatial distribution of Meew(S) amplification are also found among other OBSs. From the numerical simulations, Nakamura et al. (MGR,submitted) pointed out that the oceanic layer and the low-velocity sediment layers causes the large amplifications in low frequency range (0.1-0.2Hz) at OBSs. We conclude that the site effect of OBS characterized by such a low velocity sediment layers causes those amplification of Magnitude. 3. The frequency-dependent site factor of OBS estimated from Fourier spectrum ratio and their application for prediction of seismic intensity of land station We compare Fourier spectra of S-wave portion on OBSs with those on adjacent land stations. Station pair whose distance is smaller than 50 km is analyzed, and we obtain that spectral ratio of land station (MIEH05 of the KiK-net/NIED) to OBS (KMA01 of the DONET/JAMSTEC) is 5-20 for frequencies 10-20Hz for both

  12. Coordinated Analyses of Diverse Components in Whole Stardust Cometary Tracks

    Science.gov (United States)

    Nakamura-Messenger, K.; Keller, L. P.; Messenger, S. R.; Clemett, S. J.; Nguyen, L. N.; Frank, D.

    2011-12-01

    Analyses of samples returned from Comet 81P/Wild-2 by the Stardust spacecraft have resulted in a number of surprising findings that show the origins of comets are more complex than previously suspected. However, these samples pose new experimental challenges because they are diverse and suffered fragmentation, thermal alteration, and fine scale mixing with aerogel. Questions remain about the nature of Wild-2 materials, such as the abundances of organic matter, crystalline materials, and presolar grains. To overcome these challenges, we have developed new sample preparation and analytical techniques tailored for entire aerogel tracks [Nakamura-Messenger et al. 2011]. We have successfully ultramicrotomed entire "carrot" and "bulbous" type tracks along their axis while preserving their original shapes. This innovation allowed us to examine the distribution of fragments along the track from the entrance hole all the way to the terminal particle (TP). We will present results of our coordinated analysis of the "carrot" type aerogel tracks #112 and #148, and the "bulbous" type aerogel tracks #113, #147 and #168 from the nanometer to the millimeter scale. Scanning TEM (STEM) was used for elemental and detailed mineralogy characterization, NanoSIMS was used for isotopic analyses, and ultrafast two-step laser mass spectrometry (ultra L2MS) was used to investigate the nature and distribution of organic phases. The isotopic measurements were performed following detailed TEM characterization for coordinated mineralogy. This approach also enabled spatially resolving the target sample from fine-scale mixtures of compressed aerogel and melt. Eight of the TPs of track #113 are dominated by coarse-grained enstatite (En90) that is largely orthoenstatite with minor, isolated clinoenstatite lamellae. One TP contains minor forsterite (Fo88) and small inclusions of diopside with % levels of Al, Cr and Fe. Two of the TPs contain angular regions of fine-grained nepheline surrounded by

  13. High-Efficiency Nitride-Based Solid-State Lighting

    Energy Technology Data Exchange (ETDEWEB)

    Paul T. Fini; Shuji Nakamura

    2005-07-30

    In this final technical progress report we summarize research accomplished during Department of Energy contract DE-FC26-01NT41203, entitled ''High-Efficiency Nitride-Based Solid-State Lighting''. Two teams, from the University of California at Santa Barbara (Principle Investigator: Dr. Shuji Nakamura) and the Lighting Research Center at Rensselaer Polytechnic Institute (led by Dr. N. Narendran), pursued the goals of this contract from thin film growth, characterization, and packaging/luminaire design standpoints. The UCSB team initially pursued the development of blue gallium nitride (GaN)-based vertical-cavity surface-emitting lasers, as well as ultraviolet GaN-based light emitting diodes (LEDs). In Year 2, the emphasis shifted to resonant-cavity light emitting diodes, also known as micro-cavity LEDs when extremely thin device cavities are fabricated. These devices have very directional emission and higher light extraction efficiency than conventional LEDs. Via the optimization of thin-film growth and refinement of device processing, we decreased the total cavity thickness to less than 1 {micro}m, such that micro-cavity effects were clearly observed and a light extraction efficiency of over 10% was reached. We also began the development of photonic crystals for increased light extraction, in particular for so-called ''guided modes'' which would otherwise propagate laterally in the device and be re-absorbed. Finally, we pursued the growth of smooth, high-quality nonpolar a-plane and m-plane GaN films, as well as blue light emitting diodes on these novel films. Initial nonpolar LEDs showed the expected behavior of negligible peak wavelength shift with increasing drive current. M-plane LEDs in particular show promise, as unpackaged devices had unsaturated optical output power of {approx} 3 mW at 200 mA drive current. The LRC's tasks were aimed at developing the subcomponents necessary for packaging UCSB's light

  14. Characterization of site-effects in the urban area of Canakkale, Turkey, using ambient noise measurements

    Science.gov (United States)

    Demirci, Alper; Bekler, Tolga; Karagöz, Özlem

    2010-05-01

    The local site conditions can cause variations in the ground motion during the earthquake events. These local effects can be estimated by Nakamura method (1989) which is based on the analysis and treatment of earth vibration records by calculating the ratio of horizontal spectrum to vertical spectrum (H/V). This approach uses ambient noises and aids to estimate the dynamic soil conditions like fundamental vibration period and soil amplification of the surface layers, to characterize the seismic hazard during earthquakes and to provide detailed information for seismic microzonation in small scale urban areas. Due to these advantages, the method has been frequently used by a great number of seismologists and engineers. In this study, we aimed at explaining the soil conditions in Çanakkale and Kepez basins by using H/V technique. Çanakkale and Kepez (NW, Turkey) have fairly complex tectonic structure and have been exposed to serious earthquake damages in historical and instrumental period. Active faults, which have influence on the Çanakkale and Kepez settlements, are the Yenice-Gönen fault, Saroz-Gaziköy fault and Etili fault. It is well known that, these faults have produced high magnitude earthquakes such as 7.2 in 1912 and 7.3 in 1953. The surface geology of the surveyed area is covered by quaternary aged sediments. Sarıçay river, which originates from the eastern hilly area, accumulates sediment deposits and forms this alluvial basin. Considering the geological conditions, ambient noises were recorded at 88 measurement points which were selected to provide good coverage of the study area. All records were acquired during the midnight (between 1:00 am and 6:00 am) to reduce the artificial effects in the urban area. Taking into account the effects of undesirable traffic and industrial noises in the vicinity of measurements stations, record lengths were chosen in the range of 25-75 minutes with the sampling rate of 100 Hz. Once the required signal processes

  15. Parallel 3D Simulation of Seismic Wave Propagation in the Structure of Nobi Plain, Central Japan

    Science.gov (United States)

    Kotani, A.; Furumura, T.; Hirahara, K.

    2003-12-01

    large simulation. The parallel simulation using 256CPUs of the Earth Simulator took computer memory of 260GByte and wall-clock time of 8.3hours. Comparisons between the observed waveforms and computed simulations for two earthquakes agree well, so that it is indicating the effectiveness of the 3D model. We therefore conducted another simulation to estimate the pattern of strong ground motion during large earthquakes such as for the 1945 Mikawa earthquake. We employ the fault rupture model of Kikuchi et al (2003), which is derived from the inversion of regional records, and the pseudo dynamic source time function of Nakamura and Miyatake (2000). The simulated wavefield from the Mikawa earthquake is dominating in large surface waves at amplitude over 10cm/s and a relatively long period of 6-8s in the center of the Nobi plain. We also find directivity effect of the fault rupture from south to north in the PGV distribution and waveforms. This explains the major pattern of seismic intensity distribution and the strong motion damage during the earthquake.

  16. Strong seismic wave scattering beneath Kanto region derived from dense K-NET/KiK-net strong motion network and numerical simulation

    Science.gov (United States)

    Takemura, S.; Yoshimoto, K.

    2013-12-01

    spindle-shape S waves. Such large-scale FDM simulations are conducted on the Earth Simulator at JAMSTEC. It is found that the FDM simulation of the model without strong velocity fluctuation cannot explain the characteristics of observed S waves. By introducing strong velocity fluctuation in the LV zone, strong peak delay and spindle-shape S waves observed at central and southern part of Chiba are simulated successfully. In addition, the strong amplitude decrease of S waves in the LV zone due to strong seismic scattering is good corresponding to results based on the tomographic study of Q in Kanto (e.g., Nakamura et al., 2006). Simulation results demonstrated that strong velocity fluctuation in the LV zone plays important role in the peak delay and waveform shape. The LV zone beneath northeastern Chiba is considered as a result of dehydration from oceanic crust of subducted Philippine Sea plate (e.g., Matsubara et al., 2005). Therefore strong small-scale velocity fluctuation in the LV zone may be related with dehydrated water.

  17. Organic chemistry of cosmic dusts for understanding an intra-relationship between meteorites and comets: Toward a new frontier of astromaterial science

    Science.gov (United States)

    Yabuta, Hikaru

    2012-07-01

    and terrestrial contamination will be expected. A silica aerogel (0.03 and 0.01 g/cc) will be used for the sampling. As a ground-based experiment, we have been conducting a carefully-implemented, high-velocity double gas gun experiment of Murshison meteorite grains into a silica aerogel. It has been concluded that a major portion of aromatic carbon compositions of meteoritic organics are preserved at an impact velocity of 4 km/s, but the decrease of abundances of aliphatic carbon and slight modification of their compositions (e.g., CH2/CH3 ratio) are observed after the impact. This result will provide helpful knowledge not only for the correct interpretation of the chemical compositions of the collected IDP organics but also for that of comet dust particles collected by Stardust mission. References: [1] Brearley et al. (2006) Science 314, 1711. [2] Sandford et al. (2006) Science 314, 1720. [3] Cody et al. (2008) Meteor. Planet. Sci. 43, 353. [4] Messenger et al. (2000) Nature 404, 968. [5] Flynn et al. (2003). [6] Keller et al. (2004) GCA 68, 2577. [7] Busemann et al. (2009) EPSL 288, 44. [8] Nakamura et al. (2005) Meteor. Planet. Sci. 40, A110. [9] Duprat et al (2010) Science, 328, 742. [10] Yabuta et al. (2012) LPSC Abstract #2239

  18. Using Muon Radiography to map the Bedrock Geometry underneath an active Glacier: A Case Study in the Central Swiss Alps

    Science.gov (United States)

    Lechmann, Alessandro; Mair, David; Nishiyama, Ryuichi; Ariga, Akitaka; Ariga, Tomoko; Ereditato, Antonio; Scampoli, Paola; Vladymyrov, Mykhailo; Schlunegger, Fritz

    2016-04-01

    the Jungfrau railway tunnel that traverses the rock underneath our target glacier. In order to achieve a high angular resolution, emulsion film detectors will be used. Compared to scintillation detectors, we gain also the advantage that no in-situ power supply is needed. Lesparre, N., Gibert, D., Marteau, J., Komorowski, J.-C., Nicollin, F. and Coutant, O.: Density muon radiography of La Soufrière of Guadeloupe volcano: comparison with geological, electrical resistivity and gravity data, Geophys. J. Int., 190(2), 1008-1019, 2012. Nishiyama, R., Tanaka, Y., Okubo, S., Oshima, H., Tanaka, H. K. M. and Maekawa, T.: Integrated processing of muon radiography and gravity anomaly data toward the realization of high-resolution 3-D density structural analysis of volcanoes: Case study of Showa-Shinzan lava dome, Usu, Japan, J. Geophys. Res. Solid Earth, 119(1), 699-710, 2014. Tanaka, H. K. M., Nagamine, K., Nakamura, S. N. and Ishida, K.: Radiographic measurements of the internal structure of Mt. West Iwate with near-horizontal cosmic-ray muons and future developments, Nucl. Instruments Methods Phys. Res. Sect. A Accel. Spectrometers, Detect. Assoc. Equip., 555(1-2), 164-172, 2005.

  19. The influence of population on the economic efficiency of the metropolitan governance

    Directory of Open Access Journals (Sweden)

    Yuriy V. Pavlov

    2017-01-01

    Full Text Available Research purpose. In order to implement the optimal metropolitan governance model, it is important to understand the conditions under which this or that model is economically effective. There is a need to develop a quantitatively justified methodology for choosing the optimal metropolitan governance model for different types of metropolitan areas. It has been emphasized in some federal documents of Russia, for example, in the “Recommendations for the selection of pilot projects for approbation and improvement of mechanisms for managing the development of metropolitan areas in the Russian Federation”.Materials and methods. Domestic researchers (N. Zubarevich, K. Gonchar, etc. and foreign researchers (Glaeser Edward L., Nakamura, Ciccone A., Hall R., etc. carried out the study of quantitative relationships between the economic growth of cities and the characteristics of cities.However, for metropolitan areas, the analysis of the relationship has not yet been implemented between the outpacing economic growth of the metropolitan area relative to the average country values (labor productivity and GDP per capita, the institutional factor (the type of metropolitan governance model, andthe non-institutional factor (population size. To identify the dependencies we are interested in, we used the OECD statistical database and OECD researches to identify the metropolitan governance model in the sample of metropolitan areas in the world. The sample in this research was 87 metropolitan areas in Europe and was divided into groups, depending on the population and the introduced metropolitan governance model. For each group, a correlation-regression analysis was performed and a weighted average was calculated from the indexes of the economic growth. As the leading index of the economic growth, labor productivity was used, as the final - GDP per capita. Then a comparison was made between the real value of economic growth in each surveyed metropolitan area and

  20. Microzonation Studies In District of Dikili, Izmir (Turkey) In The Context of Social Responsibility by Using GIS Tecniques

    Science.gov (United States)

    Karabulut, Savas; Cinku, Mualla; Tezel, Okan; Hisarli, Mumtaz; Ozcep, Ferhat; Tun, Muammer; Avdan, Ugur; Ozel, Oguz; Acikca, Ahmet; Aygordu, Ozan; Benli, Aral; Kesisyan, Arda; Yilmaz, Hakan; Varici, Cagri; Ozturkan, Hasan; Ozcan, Cuneyt; Kivrak, Ali

    2015-04-01

    bearing capacity, soil amplification), c) The basin structure and possible fault of the Dikili district, d) Risk analysis on cultivated areas due to salty water injection, e) The tectonic activity of the study area from Miocene to present. During this study a number of measurements were carried out to solve the problems defined above. These measurements include; microtremor single station (H/V) method according to Nakamura's technique, which is applied at 222 points. The results provide maps of soil fundamental frequency, soil amplification and soil sedimentary thickness by using developed amprical relationships. Spatial Autocorrelation Technique (SPAC) was carried out in 11 sites with Guralp CG-5 seismometer to predict the shear wave velocity-depth model towards the sismological bedrock. Multi-channel analysis of Surface Wave (MASW), Microtremor Array Method (MAM) and Seismic Refraction Method were applied at 121 sites with SARA-Doremi Seismograph. The soil liquefaction-induced settlements are determined in the frame of shallow soil engineering problems. Vertical Electrical Sounding (VES) was carried out to define the presence of saltly and drinkable and hot/cold underground water, the location of possible faults and the bedrock depth which was estimated with a Scientrex Saris Resistivity Equipment. To define the areas which are influenced by salty water, induced polarization (IP) method was applied at 34 sites. The basin structure and the probably faults of the study area were determined by applying gravity measurements on 248 points with a CG-5 Autogravity meter. Evaluation of the combined data is very important for producing microzonation maps. We therefore integrated all of the data into the GIS database and prepared large variety of maps.

  1. PREFACE: Inverse Problems in Applied Sciences—towards breakthrough

    Science.gov (United States)

    Cheng, Jin; Iso, Yuusuke; Nakamura, Gen; Yamamoto, Masahiro

    2007-06-01

    flourishing time, it is necessary to carefully analyse the current status of inverse problems for further development. Thus we have opened with the panel discussion entitled `Future of Inverse Problems' with panelists: Professors J Cheng, H W Engl, V Isakov, R Kress, J-K Seo, G Uhlmann and the commentator: Elaine Longden-Chapman from IOP Publishing. The aims of the panel discussion were to examine the current research status from various viewpoints, to discuss how we can overcome any difficulties and how we can promote young researchers and open new possibilities for inverse problems such as industrial linkages. As one output, the panel discussion has triggered the organization of the Inverse Problems International Association (IPIA) which has led to its first international congress in the summer of 2007. Another remarkable outcome of the conference is, of course, the present volume: this is the very high quality online proceedings volume of Journal of Physics: Conference Series. Readers can see in these proceedings very well written tutorial lecture notes, and very high quality original research and review papers all of which show what was achieved by the time the conference was held. The electronic publication of the proceedings is a new way of publicizing the achievement of the conference. It has the advantage of wide circulation and cost reduction. We believe this is a most efficient method for our needs and purposes. We would like to take this opportunity to acknowledge all the people who helped to organize the conference. Guest Editors Jin Cheng, Fudan University, Shanghai, China Yuusuke Iso, Kyoto University, Kyoto, Japan Gen Nakamura, Hokkaido University, Sapporo, Japan Masahiro Yamamoto, University of Tokyo, Tokyo, Japan

  2. Effect of chain extension on rheology and tensile properties of PHB and PHB-PLA blends

    Science.gov (United States)

    Bousfield, Glenn

    Poly(3-hydroxybutyrate), referred to as PHB, is a bacterially-synthesized and biodegradable polymer which is being considered as a substitute for non-biodegradable bulk polymers like polypropylene. PHB is naturally extremely isotactic and naturally has a very high degree of crystallinity, resulting in a stiff but brittle material. The stability of PHB crystals also means that the melting point of the polymer is approximately 170°C, high with respect to similar polymers. For instance, the melting point of poly(4-hydroxybutyrate) is only 53°C (Saito, Nakamura, Hiramitsu, & Doi, 1996). Above 170°C, PHB is subject to a thermomechanical degradation mechanism, meaning that the polymer cannot be melted without degrading. One possible solution to the problem of degradation is to add a chain extender to the molten polymer to increase average molecular weight to counteract the molecular weight lost to degradation. In this work, a variety of chain extenders (JoncrylRTM ADR 4368-C, pyromellitic dianhydride, hexamethylene diisocyanate, polycarbodiimide) were compounded with a random copolymer of 98 mol% 3-hydroxybutyrate and 2 mol% 3-hydroxyvalerate (referred to as PHB) in concentrations ranging from 0.25% to 4%, to determine which chain extender functionality worked best with PHB. Molecular weight change was inferred from torque monitored during compounding, and from complex viscosity determined from parallel-plate rheology. None of the chain extenders changed the rate of degradation of PHB, although Joncryl increased the complex viscosity of the polymer. PHB was also blended with Poly(L-lactic acid), referred to as PLLA in PHB/PLLA ratios of 100/0, 75/25, 50/50, 25/75 and 0/100, to determine the effect of blending on the thermal stability of PHB. Again, thermal stability was determined by monitoring torque during compounding and by measuring complex viscosity through parallel-plate rheology. Blends in which PHB was the more abundant phase, as well as the 50% PHB/50% PLA

  3. Use of Lagrangian transport models and Sterilized High Volume Sampling to pinpoint the source region of Kawasaki disease and determine the etiologic agent

    Science.gov (United States)

    Curcoll Masanes, Roger; Rodó, Xavier; Anton, Jordi; Ballester, Joan; Jornet, Albert; Nofuentes, Manel; Sanchez-Manubens, Judith; Morguí, Josep-Anton

    2015-04-01

    quartz filters and sterilized polycarbonate membrane filters were used on sampling. Sterility conditions were required in all the processes from the preparation of the equipment, the sampling, and the later manipulation of the filter and instrumentation. The methodology used to find the possible etiological agents sources for KD cases in Japan has been extrapolated to other regions worldwide as Catalonia. In Catalonia, in the last 10 years, an average of 40 cases of KD per year are detected. Taking in consideration that in Catalonia there is a lack of a predominant strong wind or synoptic situation with high energy associated, the possible source regions of etiological agents could be much more closer to the receptors than in Japan. Therefore we have used higher resolution models for the backward simulations and a different sampling methodology based on ground measurements. References Rodó X, Curcoll R, Robinson M, Ballester J, Burns JC, Cayan,...Morguí J-A (2014) Tropospheric winds from northeastern China carry the etiologic agent of Kawasaki disease from its source to Japan. Proceedings of the National Academy of Science of the U S A, 11(22), 7952-4957 Rodo X, Ballester J, Cayan D, Melish M, Nakamura Y, et al (2011) Association of Kawasaki disease with tropospheric wind patterns. Nature Scientific Reports 1, Article Number 152 doi: 10.1038/srep00152 Stohl A, Forster C, Frank A, Seibert P, Wotawa G (2005) Technical note: The Lagrangian particle dispersion model FLEXPART version 6.2. Atmos Chem Phys 5:2461-2474

  4. La pesquería de tiburones oceánicos-costeros en los litorales de Colima, Jalisco y Michoacán

    Directory of Open Access Journals (Sweden)

    Angélica Cruz

    2011-06-01

    Full Text Available La pesquería de tiburón es una de las más importantes en el Pacífico mexicano, en la actualidad no se cuentan con los datos de la composición específica de las capturas de las diferentes flotas. En el presente trabajo se describen aspectos biológicos-pesqueros de las especies de tiburón, capturadas por la flota palangrera de mediana altura del puerto de Manzanillo, en un periodo anual de abril 2006-abril 2007, los muestreos se realizaron mensualmente a bordo de estas embarcaciones. La composición de las capturas estuvo representada por nueve especies (n=1 962, de las cuales Carcharhinus falciformis (Bibron, 1839 (88.12% sostiene esta pesquería y en segundo lugar Prionace glauca (Linnaeus, 1758 (8.21%. Las especies poco frecuentes fueron Sphyrna zygaena (Linnaeus, 1758 con (1.78%, Alopias pelagicus (Nakamura, 1935 (0.82%, Carcharhinus longimanus (Poey, 1861 (0.45%, Alopias superciliosus (Lowe, 1839 (0.35%, Carcharhinus leucas (Valenciennes, 1839 (0.1%, Carcharhinus limbatus (Valenciennes, 1839 (0.1% é Isurus oxyrinchus (Rafinesque, 1810 (0.05%. La fecundidad estimada para C. falciformis fue de 3-7 crías/hembra con tallas de 30-45cm LT; 40.57+2.03cm LT y P. glauca con 5-52 crías/hembra, con tallas de 5-18.6cm LT; 11.61±0.21cm LT. Por lo tanto se asume que C. falciformis presenta un ciclo concurrente y P. glauca probablemente un ciclo bianual consecutivo.Fishery of oceanic and coastal sharks in Colima, Jalisco and Michoacán. Shark fishery is one of the most important activities in the Mexican Pacific coast, nevertheless, there is few data available about the specific captures done by the fleet along the coast. This study describes fishery biology aspects of the shark species catched by the semi-industrial long-line fleet of Manzanillo. Monthly samplings were made on board of these vessels during an annual period from April 2006 to April 2007. Captured species composition (n=1 962 organisms was represented by nine species. The one

  5. EDITORIAL: LED light sources (light for the future) LED light sources (light for the future)

    Science.gov (United States)

    Grandjean, N.

    2010-09-01

    Generating white light from electricity with maximum efficacy has been a long quest since the first incandescent lamp was invented by Edison at the end of the 19th century. Nowadays, semiconductors are making reality the holy grail of converting electrons into photons with 100% efficiency and with colours that can be mixed for white light illumination. The revolution in solid-state lighting (SSL) dates to 1994 when Nakamura reported the first high-brightness blue LED based on GaN semiconductors. Then, white light was produced by simply combining a blue dye with a yellow phosphor. After more than a decade of intensive research the performance of white LEDs is quite impressive, beating by far the luminous efficacy of compact fluorescent lamps. We are likely close to replacing our current lighting devices by SSL lamps. However, there are still technological and fabrication cost issues that could delay large market penetration of white LEDs. Interestingly, SSL may create novel ways of using light that could potentially limit electricity saving. Whatever the impact of SSL, it will be significant on our daily life. The purpose of this special cluster issue is to produce a snapshot of the current situation of SSL from different viewing angles. In an introductory paper, Tsao and co-workers from Sandia National Laboratories, present an energy-economics perspective of SSL considering societal changes and SSL technology evolution. In a second article, Narukawa et al working at Nichia Corporation—the pioneer and still the leading company in SSL—describe the state of the art of current research products. They demonstrate record performance with white LEDs exhibiting luminous efficacy of 183 lm W-1 at high-current injection. Then, a series of topical papers discuss in detail various aspects of the physics and technology of white LEDs Carrier localization in InGaN quantum wells has been considered the key to white LEDs' success despite the huge density of defects. A

  6. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2002-04-01

    University Press, xiv + 299 pp. [Yale Southeast Asia studies monograph 48.] 1999 -Bernice de Jong Boers, Peter Just, Dou Donggo justice; Conflict and morality in an Indonesian society. Lanham, Maryland: Rowman and Littlefield, 2001, xi + 263 pp. -Nico J.G. Kaptein, Howard M. Federspiel, Islam and ideology in the emerging Indonesian state; The Persatuan Islam (PERSIS, 1923 to 1957. Leiden: Brill, 2001, xii + 365 pp. -Gerrit Knaap, Els M. Jacobs, Koopman in Azië; De handel van de Verenigde Oost-Indische Compagnie tijdens de 18de eeuw. Zutphen: Walburg Pers, 2000, 304 pp. -Toon van Meijl, Bruce M. Knauft, From primitive to postcolonial in Melanesia and anthropology. Ann Arbor: University of Michigan Press, 1999, x + 320 pp. -Jennifer Nourse, Juliette Koning ,Women and households in Indonesia; Cultural notions and social practices. Richmond, Surrey: Curzon, 2000, xiii + 354 pp., Marleen Nolten, Janet Rodenburg (eds -Sandra Pannell, Clayton Fredericksen ,Altered states; Material culture transformations in the Arafura region. Darwin: Northern Territory University Press, 2001, xiv + 160 pp., Ian Walters (eds -Anne Sofie Roald, Alijah Gordon, The propagation of Islam in the Indonesian-Malay archipelago. Kuala Lumpur: Malaysian sociological research institute, 2001, xxv + 472 pp. -M.J.C. Schouten, Mary Taylor Huber ,Gendered missions; Women and men in missionary discourse and practice. Ann Arbor: The University of Michigan Press, 1999, x + 252 pp., Nancy C. Lutkehaus (eds -Karel Steenbrink, Nakamura Mitsuo ,Islam and civil society in Southeast Asia. Singapore: Institute of Southeast Asian studies, 2001, 211 pp., Sharon Siddique, Omar Farouk Bajunid (eds -Heather Sutherland, Robert Cribb, Historical atlas of Indonesia, Richmond, Surrey: Curzon, 2000, x + 256 pp. -Sikko Visscher, Lee Kam Hing ,The Chinese in Malaysia. Kuala Lumpur: Oxford University Press, 2000, xxix + 418 pp., Tan Chee-Beng (eds -Edwin Wieringa, Jane Drakard, A kingdom of words; Language and power in Sumatra. Kuala

  7. Using the D-Wave 2X Quantum Computer to Explore the Formation of Global Terrorist Networks

    Energy Technology Data Exchange (ETDEWEB)

    Ambrosiano, John Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Roberts, Randy Mark [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sims, Benjamin Hayden [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-15

    Social networks with signed edges (+/-) play an important role in an area of social network theory called structural balance. In these networks, edges represent relationships that are labeled as either friendly (+) or hostile (-). A signed social network is balanced only if all cycles of three or more nodes in the graph have an odd number of hostile edges. A fundamental property of a balanced network is that it can be cleanly divided into 2 factions, where all relationships within each faction are friendly, and all relationships between members of different factions are hostile. The more unbalanced a network is, the more edges will fail to adhere to this rule, making factions more ambiguous. Social theory suggests unbalanced networks should be unstable, a finding that has been supported by research on gangs, which shows that unbalanced relationships are associated with greater violence, possibly due to this increased ambiguity about factional allegiances (Nakamura et al). One way to estimate the imbalance in a network, if only edge relationships are known, is to assign nodes to factions that minimize the number of violations of the edge rule described above. This problem is known to be computationally NP-hard. However, Facchetti et al. have pointed out that it is equivalent to an Ising model with a Hamiltonian that effectively counts the number of edge rule violations. Therefore, finding the assignment of factions that minimizes energy of the equivalent Ising system yields an estimate of the imbalance in the network. Based on the Ising model equivalence of the signed-social network balance problem, we have used the D-Wave 2X quantum annealing computer to explore some aspects of signed social networks. Because connectivity in the D-Wave computer is limited to its particular native topology, arbitrary networks cannot be represented directly. Rather, they must be “embedded” using a technique in which multiple qubits are chained together with special weights to

  8. PREFACE: 14th International Conference on the Physics of Highly Charged Ions (HCI 2008)

    Science.gov (United States)

    Azuma, Toshiyuki; Nakamura, Nobuyuki; Yamada, Chikashi

    2009-07-01

    Physics of Highly Charged Ions will be held in Shanghai under the organization of Professor Y Zou of Fudan University and her colleagues. We wish the organizers of HCI2010 all possible success and are looking forward to meeting you all in Shanghai. Toshiyuki Azuma, Nobuyuki Nakamura and Chikashi Yamada Editors

  9. Editorial Presentation

    Directory of Open Access Journals (Sweden)

    Ilan Avrichir

    2017-01-01

    commercial perspective "is that with the establishment of export quotas, the two countries incurred in trade losses. In "The use of competitive intelligence in the selection of export markets - a comparative analysis of four methods", Moema Pereira Nunes and Laura de Souza Lequain address one of the biggest challenges facing companies that want to export their products: How to choose an import market . Through rigorous analysis of the characteristics of four methods commonly used to perform this choice, they come to the conclusion that all of them are difficult to apply for  small and medium enterprises. While that result may be frustrating  for readers that would like to find in the paper an answer to the problem of export market selection by SMEs, the article has the great merit of drawing attention to the necessity to work in this direction. Not to mention that it serves as an advanced introduction to the knowledge of methods of analysis of import markets. In "Influences of international experience and business diversification on the degree of internationalization of Brazilian multinationals" Ivano Ribeiro, Fernando Antonio Ribeiro Serra, and Geysler Rogis Flor Bertolini analyze the impacts of two dimensions - the time of international experience and the diversification of business - on the degree of internationalization of Brazilian multinationals. Through regression analysis, they find indications that the company's business diversification is positively related to the degree of internationalization. Contrary, however, to what one would expect from established theories of internationalization of business, they find that prior international experience of Brazilian firms does not seem to predict the degree of internationalization. The authors suggest that this result may be related to the fact that the internationalization process of Brazilian multinationals is still a relatively recent phenomena. Paulo Kazuhiro Izumi, Cyro Augusto Pachicoski Couto and Mário Henrique

  10. Geology, geochemistry and fluid inclusion of Qarachilar Cu-Mo-Au quartz veins, northeast of Kharvana, East Azerbaijan

    Directory of Open Access Journals (Sweden)

    Fariba Asiay Soufiani

    2018-04-01

    ., 2015. Relationships between arc maturity and Cu-Mo-Au porphyry and related epithermal mineralization at the Cenozoic Arasbaran Magmatic Belt. Ore Geology Reviews, 65(2: 487–501. Nakamura, N., 1974. Determination of REE, Ba, Fe, Mg, Na and K in carbonaceous and ordinary Chondrites. Geochimica et Cosmochimica Acta, 38(5: 755–773. Simmonds, V. and Moazzen, M., 2015. Re–Os dating of molybdenites from Oligocene Cu–Mo–Au mineralized veins in the Qarachilar area, Qaradagh batholith (northwest Iran: implications for understanding Cenozoic mineralization in South Armenia, Nakhchivan, and Iran. International Geology Review, 57(3: 290–304.

  11. Foreword [IJEGMBE 2015: India-Japan expert group meeting on biomolecular electronics and organic nanotechnology for environment preservation, Fukuoka (Japan), 23-26 December 2015

    International Nuclear Information System (INIS)

    2016-01-01

    There is increased interest in organic nanotechnology and biomolecular electronics for environmental preservation, and in their anticipated impact on the economics of both the developing and the developed world. Keeping this in mind, the Department of Biological Functions, Graduate School of Life Sciences and Systems Engineering, Kyushu Institute of Technology (KIT), Kitakyushu, Japan, and the Department of Science and Technology Centre on Biomolecular Electronics (DSTCBE), National Physical Laboratory (NPL) jointly organized the India-Japan Workshop on Biomolecular Electronics and Organic Nanotechnology for Environmental Preservation (IJWBME 2009) at NPL, New Delhi from 17 th - 19 th December 2009, IJWBME 2011 at EGRET Himeji, Himeji, from 7 th - 10 th December, Japan, and IJWBME 2013 at Delhi Technological University, New Delhi, from 13 th - 15 th December. The India-Japan Expert Group Meeting on Biomolecular Electronics and Organic Nanotechnology for Environment Preservation (IJEGMBE) will be held from 22 th – 25 th , December, 2015, at Nakamura Centenary Memorial Hall, Kyushu Institute of Technology, Kitakyushu, Japan in association with Delhi Technological University, Delhi, India. Recent years have seen rapid growth in the area of Biomolecular Electronics involving the association and expertise of physicists, biologists, chemists, electronics engineers and information technologists. There is increasing interest in the development of nanotechnology and biomolecular electronic devices for the preservation of our precious environment. In this context, the world of the electronics, which developed on Si semiconductors, is going to change drastically. A paradigm shift towards organic or printed electronics is more likely in the future. The field of organic electronics promises exciting new technologies based on inexpensive and mechanically flexible electronic devices, and is now starting to see commercial success. On the sidelines of this increasingly well

  12. Generation of high reactive fluids by rapid clinopyroxene-seawater interaction: An experimental study at 425 °C, 40 and 100 MPa

    Science.gov (United States)

    Beermann, Oliver; Garbe-Schönberg, Dieter; Schächinger, Steffen; Arzi, Lisa; Holzheid, Astrid

    2014-05-01

    experiments significant amounts (~10-20 rel. %) of secondary mineral phases, i.e. talc, the serpentine-group minerals lizardite, antigorite, and chrysotile, and minor abundances of pyrrhotite and pentlandite were formed primarily on Cpx even after short run durations of 3 hours. Our results show that intense leaching of Ca, REEs, transition and trace metals only occurred with Cpx and only in the seawater experiments. Leaching was caused by rapid precipitation of the intitial seawater Mg (1400 ppm) on Cpx, which generated HCl(aq) with pH (25 °C) leaching. Because element exchange reactions between seawater and the other widespread abundant mineral olivine in the oceanic lithosphere are very sluggish at elevated pressure and temperature conditions [10], we conclude that in particular seawater interactions with un-leached pyroxenes creates high element fluxes during early-stage, high temperature MOR hydrothermalism, as it is evident from MAR 5° S fluids. This kind of hydrothermalism is expected to be not uncommon in particular at the slow-spreading MAR [9], and the high element fluxes here, most probably caused by seawater-pyroxene interactions, should be taken into account when modelling global chemical fluxes of MOR hydrothermalism. References: [1] German C. R., Thurnherr A. M., Knoery J., Charlou J.-L., Jean-Babtiste P., and Edmonds H. N. (2010) Deep Sea Res. 157, 518-527. [2] Schmidt K., Garbe-Schönberg D., Bau M., and Koschinsky A. (2010) Geochim. Cosmochim. Acta 74, 4058-4077. [3] Saito M. A., Noble A. E., Tagliabue A., Goepfert T. G., Lamborg C. H., and Jenkins W. J. (2013) Nat. Geosci. 5, 775-779. [4] German C. R., Bennett S. A., Connelly D. P., Evans A. J., Murton B. J., Parson L. M., Prien R. D., Ramirez-Llodra E., Jakuba M., Shank T. M., Yoerger D. R., Baker E. T., Walker S. L., and Nakamura K. (2008) Earth. Planet. Sci. Lett. 273, 332-344. [5] Haase K. M., Petersen S., Koschinsky A., and M64/1, M68/1 Scient. Parties (2007) Geochem. Geophys. Geosyst. 8, Q11002, doi

  13. First LOCSMITH locations of deep moonquakes

    Science.gov (United States)

    Hempel, S.; Knapmeyer, M.; Sens-Schönfelder, C.; Oberst, J.

    2008-09-01

    stacking we developed a complex multiparameter correlation algorithm to calculate the optimum time shift. Results We present relocations of selected deep moonquakes in context of data availability and quality. Previous locations are often contained in our location clouds, but realistic location uncertainties allow large deviations from the best fitting solutions, including locations on the far side of the Moon. Perspective By developing new methods for data processing and using the LOCSMITH locating algorithm we hope to reduce the location uncertainty sufficiently to make sure that all sources are on the near side, or to prove a far side origin of some of them. This would answer questions of hemispheric symmetry of lunar deep seismicity and the Moon's internal structure. References [1] Knapmeyer (2008) accepted to GJI. [2] Nakamura (2005) JGR, 110, E01001. [3] Lognonné (2003) EPSL, 211, 2744. [4] Bulow (2005) JGR, 110, E10003. [5] Sonnemann (2005) EGU05A07960. [6] Hempel, Knapmeyer, Oberst (2008) EGU2008A07989.

  14. PREFACE: 15th International Conference on the Physics of Highly Charged Ions

    Science.gov (United States)

    Zou, Yaming; Hutton, Roger

    2011-07-01

    , under the Chairmanship of Professors Thomas Stoehlker and Joachim Ullrich. We wish them all the best with their plans and look forward to meeting you all again in 2012. Committees, Exhibitors and Sponsors HCI2010 International Advisory Committee F Aumayr (Austria) T Azuma (Japan) P Beiersdorfer (USA) J Burgdoerfer (Austria) A Cassimi (France) H Cederquist (Sweden) J Costello (Ireland) F Currell (UK) R Hoekstra (Holland) X Ma (China) F Martín (Spain) A Mueller (German) N Nakamura (Japan) M Pajek (Poland) R Rivarola (Argentina) Z Rudzikas (Lithuania) V Shabaev (Russia) R Schuch (Sweden) T Stoehlker (Germany) J Tanis (USA) L Tribedi (India) K Tokési (Hungary) J Ullrich (Germany) D Vernhet (France) Y Zou (China) T Zouros (Greece) HCI2010 Local Organizing Committee Co-chairs: Yaming Zou and Roger Hutton (Fudan university) Secretaries: Baoren Wei and Yunqing Fu (Fudan University) Treasurers: Xiuqing Xu and Daoli Xu (Shanghai Nuclear Society) Members Chongyang Chen (Shanghai) Jianmin Yuan (Changsha) Jun Yan (Beijing) Chenzhong Dong (Lanzhou) Xiaohong Cai (Lanzhou) Xinwen Ma (Lanzhou) Xuru Duan (Sichuan) Baohan Zhang (Sichuan) Exhibitors Andor Technology andor.com Shanghai Kelin Technology Development Co. Ltd chnkelin.com Varian Inc. varianinc.com Sponsors Natural Science Foundation of China International Union of Pure and Applied Physics (IUPAP) Fudan University

  15. PREFACE: Selected contributions from the 3rd Theory Meets Industry International Workshop, TMI2009 (Nagoya, Japan, 11-13 November 2009) Selected contributions from the 3rd Theory Meets Industry International Workshop, TMI2009 (Nagoya, Japan, 11-13 November 2009)

    Science.gov (United States)

    Tanaka, Isao; Hafner, Jürgen; Wimmer, Erich; Asahi, Ryoji

    2010-09-01

    . Lectures and poster presentations were thus solicited from leading international academic and industrial researchers. The large audience that attended responded to the high quality of the talks with pertinent questions and lively discussions. The third workshop, TMI2009, was held over three days from 11-13 November, 2009, at the Nagoya International Center, Nagoya, Japan. Invited talks were given by 23 speakers from 9 countries from both the academic and industry sectors. The speakers were Ryoji Asahi (Toyota Central R&D Labs, Japan), Tomas Bucko (University of Vienna, Austria), Gábor Csányi (University of Cambridge, UK), Alessandro De Vita (King's College London, UK), Bernard Delley (Paul Scherrer Institute, Switzerland), Christophe Domain (EDF, France), George Fitzgerald (Accelrys, USA), Takeo Fujiwara (University of Tokyo, Japan), Jürgen Hafner (University of Vienna, Austria), Masaya Ishida (Sumitomo Chemicals, Japan), Werner Janse Van Rensburg (Sasol Technology, South Africa), Masanori Kohyama (AIST, Japan), Takao Kotani (Tottori University, Japan), Georg Kresse (University of Vienna, Austria), Katsuyuki Matsunaga (Kyoto University, Japan), Stefan Müller (University of Erlangen-Nuremberg, Germany), Shin-ichiro Nakamura (Mitsubishi Chemicals, Japan), Fumiyasu Oba (Kyoto University, Japan), Tamio Oguchi (Hiroshima University, Japan), Pascal Raybaud (IFP, France), Isao Tanaka (Kyoto University/JFCC, Japan), Göran Wahnström (Chalmers University of Technology, Sweden), and Erich Wimmer (Materials Design Inc., USA). There were 40 poster presentations in total. The workshop was attended by approximately 120 participants with approximately 50 per cent from industry. The invited talks covered advances in ab initio solid-state calculations and their practical use in industry. Presentations outlining the progress made in treating large and complex systems, as well as more accurate and efficient calculation methods, were given from the theory side. Examples of the use of ab

  16. PREFACE: International Conference on Inverse Problems 2010

    Science.gov (United States)

    Hon, Yiu-Chung; Ling, Leevan

    2011-03-01

    Sciences, South KoreaYu Jiang, Hokkaido University, JapanDe-Xing Kong, Zhejiang University, ChinaOlga Krivorotko, Novosibirsk State University, RussiaPhilipp Küegler, Austrian Academy of Sciences, AustriaKiwoon Kwon, Dongguk University, South KoreaChun-Kong Law, National Sun Yat-sen University, TaiwanJune-Yub Lee, Ewha Womans University, South KoreaMing Li, City University of Hong Kong, HKSARMikyoung Lim, Korea Advanced Institute of Science and Technology (KAIST), South KoreaJijun Liu, Southeast University, ChinaXiaodong Liu, Chinese Academy of Sciences, ChinaFuming Ma, Jilin University, ChinaHang Ma, Shanghai University, ChinaValdemar Melicher, Ghent University, BelgiumGen Nakamura, Hokkaido University, JapanLong Tuan Nguyen, Ruhr-Universitat Bochum, GermanyEtibar Panakhov, Firat University, TurkeyRobert Plato, University of Siegen, GermanyJean-Pierre Puel, The University of Tokyo, JapanHans-Jürgen Reinhardt, University of Siegen, GermanyMaxim Shishlenin, Sobolev Institute of Mathematics, RussiaIlya Silvestrov, Institute of Petroleum Geology and Geophysics SB RAS, RussiaMourad Sini, Austrian Academy of Sciences, AustriaJán Sládek, Slovak Academy of Sciences, SlovakiaZhijun Tan, Sun Yat-sen University, ChinaQuan-Fang Wang, The Chinese University of Hong Kong, HKSARWenyan Wang, The University of Tokyo, JapanPihua Wen, Queen Mary, University of London, UKZhihai Xiang, Tsinghua University, ChinaXiang-Tuan Xiong, Northwest Normal University, ChinaDinghua Xu, Zhejiang Sci-Tech University, ChinaYongzhi Steve Xu, University of Louisville, USAJiaqing Yang, Chinese Academy of Sciences, ChinaJian Zhang, Sichuan Normal University, ChinaYing Zhang, Fudan University, ChinaTing Zhou, University of Washington, USAJianxin Zhu, Zhejiang University, China Advisory BoardH Thomas Banks, North Carolina State University, USATony F Chan, The Hong Kong University of Science and Technology, HKSARHeinz W Engl, Johannes Kepler Universitát Linz, AustriaRainer Kress, Georg-August-Universitát G

  17. PREFACE: Exploring surfaces and buried interfaces of functional materials by advanced x-ray and neutron techniques Exploring surfaces and buried interfaces of functional materials by advanced x-ray and neutron techniques

    Science.gov (United States)

    Sakurai, Kenji

    2010-12-01

    measurement. Advances in such technologies are bringing with them new opportunities in surface and buried interface science. In the not too distant future, we will publish a special issue or a book detailing such progress. Exploring surfaces and buried interfaces of functional materials by advanced x-ray and neutron techniques contents Lateral uniformity in chemical composition along a buried reaction front in polymers using off-specular reflectivity Kristopher A Lavery, Vivek M Prabhu, Sushil Satija and Wen-li Wu Orientation dependence of Pd growth on Au electrode surfaces M Takahasi, K Tamura, J Mizuki, T Kondo and K Uosaki A grazing incidence small-angle x-ray scattering analysis on capped Ge nanodots in layer structures Hiroshi Okuda, Masayuki Kato, Keiji Kuno, Shojiro Ochiai, Noritaka Usami, Kazuo Nakajima and Osami Sakata High resolution grazing-incidence in-plane x-ray diffraction for measuring the strain of a Si thin layer Kazuhiko Omote X-ray analysis of mesoporous silica thin films templated by Brij58 surfactant S Fall, M Kulij and A Gibaud Review of the applications of x-ray refraction and the x-ray waveguide phenomenon to estimation of film structures Kouichi Hayashi Epitaxial growth of largely mismatched crystals on H-terminated Si(111) surfaces Hidehito Asaoka Novel TiO2/ZnO multilayer mirrors at 'water-window' wavelengths fabricated by atomic layer epitaxy H Kumagai, Y Tanaka, M Murata, Y Masuda and T Shinagawa Depth-selective structural analysis of thin films using total-external-reflection x-ray diffraction Tomoaki Kawamura and Hiroo Omi Structures of Yb nanoparticle thin films grown by deposition in He and N2 gas atmospheres: AFM and x-ray reflectivity studies Martin Jerab and Kenji Sakurai Ga and As composition profiles in InP/GaInAs/InP heterostructures—x-ray CTR scattering and cross-sectional STM measurements Yoshikazu Takeda, Masao Tabuchi and Arao Nakamura Polarized neutron reflectivity study of a thermally treated MnIr/CoFe exchange bias system Naoki

  18. PREFACE: Rutherford Centennial Conference on Nuclear Physics

    Science.gov (United States)

    Freeman, Sean

    2012-09-01

    Dobacewski (Warsaw, Poland) G Dracoulis (ANU, Australia) S J Freedman (LBL, USA) M Hass (Weizmann Institute, Israel) M Huyse (Leuven, Belgium) P Jones (Birmingham, UK) D Khao (Hanoi, Vietnam) R Krücken (Munich, Germany) K Langanke (Darmstadt, Germany) C Lister (Argonne, USA) G A Miller (University of Washington, USA) D Morrissey (MSU, USA) T Motobayashi (RIKEN, Japan) S Nagamiya (J-PARC, Japan) W Nazarewicz (ORNL, USA) S Mullins (iThemba, South Africa) T Nakamura (Tokyo, Japan) P Roussel Chomaz (GANIL, France) R Ribas (Sao Paolo, Brazil) M Vanderhaeghen (Mainz, Germany) U Wiedner (Uppsala, Sweden) F Xu (Peking University, China) Q Zhao (IHEP, Bejing) W Zajc (Columbia, USA)

  19. EDITORIAL: From reciprocal space to real space in surface science From reciprocal space to real space in surface science

    Science.gov (United States)

    Bartels, Ludwig; Ernst, Karl-Heinz

    2012-09-01

    Triest.let's finish—aus basta Some move atoms around to hear how they sound.Karl-Heinz Rieder, Erice, 6 April 1998 From reciprocal space to real space in surface science contents From reciprocal space to real space in surface scienceLudwig Bartels and Karl-Heinz Ernst Karl-Heinz Reider: the quiet pioneerGiorgio Benedek Scattering of CO and N2 molecules by a graphite surfaceJunepyo Oh, Takahiro Kondo, Keitaro Arakawa, Yoshihiko Saito, Junji Nakamura, W W Hayes and J R Manson Helium, neon and argon diffraction from Ru(0001)M Minniti, C Díaz, J L Fernández Cuñado, A Politano, D Maccariello, F Martín, D Farías and R Miranda Enhanced charge transfer in a monolayer of the organic charge transfer complex TTF-TNAP on Au(111)T R Umbach, I Fernandez-Torrente, J N Ladenthin, J I Pascual and K J Franke Extended pattern recognition scheme for self-learning kinetic Monte Carlo simulationsSyed Islamuddin Shah, Giridhar Nandipati, Abdelkader Kara and Talat S Rahman Acetylene on Cu(111): imaging a molecular surface arrangement with a constantly rearranging tipYeming Zhu, Jonathan Wyrick, Kamelia D Cohen, Katie Marie Magnone, Connor Holzke, Daniel Salib, Quan Ma, Dezheng Sun and Ludwig Bartels Coulomb attraction during the carpet growth mode of NaClFriederike Matthaei, Sarah Heidorn, Konrad Boom, Cord Bertram, Ali Safiei, Jörg Henzl and Karina Morgenstern Molecular self-assembly on an insulating surface: interplay between substrate templating and intermolecular interactionsMarkus Kittelmann, Philipp Rahe and Angelika Kühnle Vertical manipulation of native adatoms on the InAs(111)A surfaceJ Yang, C Nacci, J Martínez-Blanco, K Kanisawa and S Fölsch Charge transfer between isomer domains on n+-doped Si(111)-2 × 1: energetic stabilizationR M Feenstra, G Bussetti, B Bonanni, A Violante, C Goletti, P Chiaradia, M G Betti and C Mariani Probing the properties of metal-oxide interfaces: silica films on Mo and Ru supportsLeonid Lichtenstein, Markus Heyde, Stefan Ulrich, Niklas Nilius

  20. REPORT FROM THE ORGANIZERS: The 25th International Conference on Low Temperature Physics

    Science.gov (United States)

    Kes, Peter

    2009-03-01

    recipients of the most important prize in low temperature physics, the Fritz London Memorial Prize 2008, were Yuriy M Bunkov (Institute Neël, Grenoble), Vladimir V Dmitriev, and Igor A Fomin (both Kapitza Institute, Moscow). They got the prize for their discovery and understanding of the 'Phase Coherent Spin Precession and Spin Superfluidity of 3He-B'. The Simon Prize 2008 of The Physical Society went to Yasunobu Nakamura and Jaw-Shen Tsai (NEC Laboratories, Tsukuba) for their 'Pioneering demonstration of quantum coherent behaviour in a macroscopic object and for their subsequent explorations of quantum coherent physics in a series of novel superconducting devices'. The Nicholas Kurti European Science Prize (sponsored by Oxford Instruments) was awarded to Lieven Vandersypen (Delft University of Technology) for his 'Ground-breaking work on the coherent control of nuclear and electron spins, with possible application to quantum information processing'. Finally, the first IUPAP Young Scientist Prizes in Low Temperature Physics went to Kostya Novoselov (University of Manchester) for his 'Contribution in the discovery of graphene and for pioneering studies of its extraordinary properties', to Dai Aoki (Tohuko University, Sendai) for his 'Discovery of novel heavy fermion superconductivity in actinide compounds', and to Viktor Tsepelin (Lancaster University) for 'The development of new experimental techniques and key discoveries in the fields of 3He crystals and quantum turbulence'. All prize recipients got the opportunity to present their work in an invited oral contribution. As is common practice nowadays all announcements, registrations, paper submissions and communications regarding program and practical matters were done electronically, either by email or via internet. Nevertheless, the program book was still printed and handed out to all participants at registration and they received an electronic version on a USB stick as well. The stick also contained all the submitted

  1. Report from the organizers Report from the organizers

    Science.gov (United States)

    Kes, Peter

    2009-04-01

    conferences time is reserved for prize ceremonies. The recipients of the most important prize in low temperature physics, the Fritz London Memorial Prize 2008, were Yuriy M Bunkov (Institute Néel, Grenoble), Vladimir V Dmitriev, and Igor A Fomin (both Kapitza Institute, Moscow). They got the prize for their discovery and understanding of the 'phase coherent spin precession and spin superfluidity of 3He-B'. The Simon Prize 2008 of The Physical Society went to Yasunobu Nakamura and Jaw-Shen Tsai (NEC Laboratories, Tsukuba) for their 'pioneering demonstration of quantum coherent behaviour in a macroscopic object and for their subsequent explorations of quantum coherent physics in a series of novel superconducting devices'. The Nicholas Kurti European Science Prize (sponsored by Oxford Instruments) was awarded to Lieven Vandersypen (Delft University of Technology) for his 'ground-breaking work on the coherent control of nuclear and electron spins, with possible application to quantum information processing'. Finally, the first IUPAP Young Scientist Prizes in Low Temperature Physics went to Kostya Novoselov (University of Manchester) for his 'contribution in the discovery of graphene and for pioneering studies of its extraordinary properties', to Dai Aoki (Tohuko University, Sendai) for his 'discovery of novel heavy fermion superconductivity in actinide compounds', and to Viktor Tsepelin (Lancaster University) for 'the development of new experimental techniques and key discoveries in the fields of 3He crystals and quantum turbulence'. All prize recipients got the opportunity to present their work in an invited oral contribution. As is common practice nowadays all announcements, registrations, paper submissions and communications regarding program and practical matters were done electronically, either by email or via the internet. Nevertheless, the program book was still printed and handed out to all participants at registration and they received an electronic version on a USB

  2. Chiral Dynamics 2006

    Science.gov (United States)

    Ahmed, Mohammad W.; Gao, Haiyan; Weller, Henry R.; Holstein, Barry

    2007-10-01

    of singular potentials and power counting / M.P. Valderrrama. The challenge of calculating Baryon-Baryon scattering from lattice QCD / S.R. Beane. Precise absolute np scattering cross section and the charged [Pie symbol] NN coupling constant / S. E. Vigdor. Probing hadronic parity violation using few nucleon systems / S.A. Page. Extracting the neutron-neutron scattering length from neutron-deuteron breakup / C.R. Howell. Extraction of [equationl] from [Pie symbol]-d --> [equation] / A. Grudestig. The three- and four-body system with large scattering length / L. Platter. 3N and 4N systems and the Ay puzzle / T. Clegg. Recent progress in nuclear lattice simulations with effective field theory / D. Lee. Few-body studies at KVI / J.G. Messchendorp. Results of three nucleon experiments from RIKEN / K. Sekiguchi. A new opportunity to measure the total photoabsorption cross section of helium / P. T. Debevec. Three-body photodisintegration of 3He with double polarizations / X. Zong. Large two-pion exchange contributions to the pp --> pp[Pie symbol]0 reaction / F. Myhrer. Towards a systematic theory of nuclear forces / E. Epelbaum. Ab initio calculations of eletromagnetic reactions in light nuclei / W. Leidemann. Electron scattering from a polarized deuterium target at BLAST / R. Fatemi. Neutron-neutron scattering length from the reaction [equation] / V. Lensky. Renormalization group analysis of nuclear current operators / S.X. Nakamura. Recent results and future plans at MAX-LAB / K.G. Fissum. Nucleon polarizabilities from deutron compton scattering, and its lessons for chiral power counting / H. W. Grie hammer. Compton scattering on HE-3 / D. Choudhury -- pt. D. Hadron structure and Meson-Baryon interactions. Summary of the working group on Hadron structure and Meson-Baryon interactions / G. Feldman and T.R. Hemmert. Finite volume effects: lattice meets CHPT / G. Schierholz. Lattice discretization errors in chiral effective field theories / B.C. Tiburzi. SU(3)-breaking

  3. Transmission eigenvalues

    Science.gov (United States)

    Cakoni, Fioralba; Haddar, Houssem

    2013-10-01

    iterative least square method to identify the spherically stratified index of refraction from transmission eigenvalues. On the characterization of transmission eigenvalues in terms of far-field measurements, a promising new result is obtained by Kirsch and Lechleiter [21] showing how one can identify the transmission eigenvalues using the eigenvalues of the scattering operator which are available in terms of measured scattering data. In the paper by Kleefeld [22], an accurate method for computing transmission eigenvalues based on a surface integral formulation of the interior transmission problem and numerical methods for nonlinear eigenvalue problems is proposed and numerically validated for the scalar problem in three dimensions. On the other hand, the paper by Sun and Xu [23] investigates the computation of transmission eigenvalues for Maxwell's equations using a standard iterative method associated with a variational formulation of the interior transmission problem with an emphasis on the effect of anisotropy on transmission eigenvalues. From the perspective of using transmission eigenvalues in non-destructive testing, the paper by Cakoni and Moskow [24] investigates the asymptotic behavior of transmission eigenvalues with respect to small inhomogeneities. The paper by Nakamura and Wang [25] investigates the linear sampling method for the time dependent heat equation and analyses the interior transmission problem associated with this equation. Finally, in the paper by Finch and Hickmann [26], the spectrum of the interior transmission problem is related to the unique determination of the acoustic properties of a body in thermoacoustic imaging. We hope that this collection of papers will stimulate further research in the rapidly growing area of transmission eigenvalues and inverse scattering theory.

  4. PREFACE: Dynamics of low-dimensional systems Dynamics of low-dimensional systems

    Science.gov (United States)

    Bernasconi, M.; Miret-Artés, S.; Toennies, J. P.

    2012-03-01

    Chulkov Surface phonons on Pb(111) I Yu Sklyadneva, R Heid, K-P Bohnen, P M Echenique and E V Chulkov Using evidence from nanocavities to assess the vibrational properties of external surfaces G F Cerofolini, F Corni, S Frabboni, G Ottaviani, E Romano, R Tonini and D Narducci Magnetic properties and relaxation dynamics of a frustrated Ni7 molecular nanomagnet E Garlatti, S Carretta, M Affronte, E C Sañudo, G Amoretti and P Santini A theoretical study of rotational and translational diffusion dynamics of molecules with a six-fold point symmetry adsorbed on a hexagonal lattice by neutron scattering I Calvo-Almazán, S Miret-Artés and P Fouquet Vibrational dynamics and surface structure of Bi(111) from helium atom scattering measurements M Mayrhofer-Reinhartshuber, A Tamtögl, P Kraus, K H Rieder and W E Ernst Double and triple ionization of silver clusters by electron impactAvik Halder, Anthony Liang, Chunrong Yin and Vitaly V Kresin Scattering of O2 from a graphite surface W W Hayes, Junepyo Oh, Takahiro Kondo, Keitaro Arakawa, Yoshihiko Saito, Junji Nakamura and J R Manson Zero-phonon lines of systems with different dimensions and unconventional vibronic interactions V Hizhnyakov A kinetic Monte Carlo approach to investigate antibiotic translocation through bacterial porins Matteo Ceccarelli, Attilio V Vargiu and Paolo Ruggerone Quantum Zeno and anti-Zeno effects in surface diffusion of interacting adsorbates H C Peñate-Rodrìguez, R Martìnez-Casado, G Rojas-Lorenzo, A S Sanz and S Miret-Artés Weakly bound finite systems: (4He)N-Rb2(3Σu), clustering structures from a quantum Monte Carlo approach D López-Durán, R Rodrìguez-Cantano, T González-Lezana, G Delgado-Barrio, P Villarreal, E Yurtsever and F A Gianturco Multiphonon atom-surface scattering from corrugated surfaces: derivation of the inelastic scattering spectrum for diffraction statesBranko Gumhalter Probing the non-pairwise interactions between CO molecules moving on a Cu(111) surfacePepijn R Kole, Holly

  5. PREFACE: Nanosafe2010: International Conference on Safe Production and Use of Nanomaterials

    Science.gov (United States)

    Sentein, Carole; Schuster, Frédéric; Tardif, François

    2011-07-01

    ESevertsov Inst. of Ecology and Evolution, RU KÜCK AUniv. Bremen, DE KUO Y-MChung Hwa University, TW KVITEK LPalacky Univ., CZ LABILLE JCEREGE, FR LAMMINEN EDekati, FI LARUE CCEA, FR LE BIHAN OINERIS, FR LE DUR DEcomesure, FR LECERF PCILAS, FR LEGRAND MCordouan, FR LELONG CUJF CEA, FR LIMOUSIN SINERIS, FR LINDELOEV JGEA Process Engineering, DK LIU P PChina Jiliang University, CN LIU WCEREGE, FR MACHEREY A-CCNRS, FR MAGGA YCEA, FR MAHLENDORF FUniversity Duisburg-Essen, DE MANIER NINERIS, FR MANZO LUniv. Pavia, IT MARCHETTO ACEA, FR MARCONE GUNICAMP, BR MARI DEPFL, CH MARIE-DESVERGNE CCEA, FR MARIE-LOUISE APSA Peugeot-Citroen, FR MARMUSE LNano-H S.A.S., FR MARRA JPhilips Research Aerasense, NL MASION ACEREGE, FR MATEI EPolitehnica University Bucharest, RO MATSUI YKyoto Univ., JP MATZKE MUniv. Gothenburg, SE MAYNE-L'HERMITE MCEA, FR MELINTE G ABabes-Bolyai University, RO MERINO CGrupo Antolin Ingenieria, ES MICHAUD-SORET ICEA, FR MICHELETTI CJRC, IT MONTIGEL EBasler Versicherungen, CH MONTOYA ERAMEM, ES MOSSUZ VCEA, FR MOTELLIER SCEA, FR MOTZKUS CLNE, FR MUIR BNaneum, GB NAKAMURA KJAPAN NUS CO., JP NEUBAUER NKarlsruhe Institute of Technologie, DE NEUMEISTER LBG ETEM, DE NGUYEN TNIST, US NIORT NINTERTEK, FR NOIRTIN AINTERTEK, FR NOWACK BEmpa, CH NYEMBE DUniv. Johannesburg, ZA Ó CLAONADH NDublin Institute of Technology, IE OBERDÖRSTER GUniv. Rochester, US OGURA IAIST, JP OSTIGUY CIRSST, CA OTSUKA KJFE Techno-Research Corp., JP OUF F-XIRSN, FR OUSACI SALMA, FR PAGET VCEA, FR PAILLEUX MEcole des Mines de Saint Etienne, FR PANDARD PINERIS, FR PANZER OEuropean Research Services, DE PARISELLI FCNRS, FR PERLET JNANO Magazine, GB PETERS RRIKILT, NL PETIT A-NCEA, FR PETKOVIC JNational Institute of Biology, SI PIMENOFF JBeneq, FI PINAULT MCEA, FR PIRET J-PUniv. Namur, BE PONTONE RTekna Plasma Systems, FR POURCHEZ JEcole des Mines de Saint Etienne, FR PRAETORIUS AETH Zurich, CH PRAT OCEA, FR PREVENSLIK TQED Radiations, CN PREVOST CIRSN, FR PROY HUART DFrance Nature Environnement, FR PUI

  6. PREFACE: XVth International Conference on Calorimetry in High Energy Physics (CALOR2012)

    Science.gov (United States)

    Akchurin, Nural

    2012-12-01

    /Saclay Irfu/SPP FRANCAVILLA, Paolo IFAE Barcelona GATAULLIN, Marat California Institute of Technology GATTO, Corrado INFN-Napoli GAUDIO, Gabriella INFN-Pavia GERMANI, Stefano INFN-Perugia Goldenzweig, Pablo University of Rochester GRAF, Norman SLAC National Accelerator Laboratory GROOM, Don Lawrence Berkeley Lab GUARDINCERRI, Elena Los Alamos National Laboratory HAUPTMAN, John Iowa State University HENRIQUES, Ana CERN HUANG, Jin Los Alamos National Laboratory HU, Tao IHEP-Beijing, CAS JIANG, Xiaodong Los Alamos National Laboratory JUI, Charles University of Utah KAPUSTINSKY, Jon Los Alamos National Laboratory KIBILKO, Mark SE Technical Sales, Inc. KIRSCHENMANN, Henning University of Hamburg KISTENEV, Edouard Brookhaven National Laboratory KLIMEK, Pawel Stockholm Universitet KROEGER, Robert University of Mississippi LECOQ, Paul CERN LEE, Sehwook Texas Tech University LEE, Sung-Won Texas Tech University LIVAN, Michele Pavia University LUTZ, Benjamin DESY MAGILL, Stephen Argonne National Laboratory MATHIS, Mark College of William and Mary MATTHEWS, John University of Utah MENKE, Sven Max-Planck-Institut fuer Physik MOULSON, Matthew INFN-Frascati NAGEL, Martin Max-Planck-Institut fuer Physik NAKAMURA, Isamu KEK NEMECEK, Stanislav FZU AVCR Praha NESSI-TEDALDI, Francesca ETH Zurich NOVOTNY, Rainer 2nd Physics Institute, University Giessen OREGLIA, Mark University of Chicago PERLOFF, Alexx Texas A&M University PETYT, David Rutherford Appleton Laboratory RAHMAT, Rahmat University of Mississippi RAMILLI, Marco Hamburg Universitaet ROSIER LEES, Sylvie LAPP- IN2P3-CNRS RUTHERFOORD, John University of Arizona SAKUMA, Tai Texas A&M University SANTIAGO CERQUEIRA, Augusto Federal University of Juiz de Fora SARRA, Ivano INFN-Frascati SEIDEL, Sally University of New Mexico SEIFERT, Frank TU Dresden, Germany SHAMIM, Mansoora University of Oregon SIMON, Frank Max-Planck-Institute for Physics STAFFAN, Paul Wiener Plein and Baus, Corp Dr. STAROVOITOV, Pavel DESY TABARELLI DE FATIS, Tommaso

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