Hanford site as it relates to an alternative site for the Waste Isolation Pilot Plant: an environmental description

International Nuclear Information System (INIS)

Fecht, K.R.

1978-12-01

The use of basalt at Hanford as an alternative for the Waste Isolation Pilot Plant (WIPP) would require that the present Basalt Waste Isolation Program (BWIP) at Hanford be expanded to incorporate the planned WIPP functions, namely the permanent storage of transuranic (TRU) wastes. This report discusses: program costs, demography, ecology, climatology, physiography, hydrology, geology, seismology, and historical and archeological sites

2101-M pond closure plan. Volume 1, Revision 2

Energy Technology Data Exchange (ETDEWEB)

Izatt, R. D.; Lerch, R. E.

1993-06-01

This document describes activities for the closure of a surface impoundment (2101-M Pond) at the Hanford Site. The 2101-H Pond was initially constructed in 1953 to serve as a drainage collection area for the 2101-H Building. (Until the Basalt Waste Isolation Project (BWIP) Laboratory was constructed in the 2101-M Building in 1979--1981, the only source contributing discharge to the pond was condensate water from the 2101-H Building heating, ventilation, and air conditioning (HVAC) system. The drains for the BWIP Laboratory rooms were plumbed into a 4-in., cast-iron, low-pressure drain pipe that carries waste water from the HVAC system to the pond. During the active life of the BWIP Laboratory, solutions of dissolved barium in groundwater samples were discharged to the 2101-M Pond via the laboratory drains. As a result of the discharges, a Part A permit application was initially submitted to the Washington State Department of Ecology (Ecology) in August 1986 which designates the 2101-M Pond as a surface impoundment.

2101-M pond closure plan

International Nuclear Information System (INIS)

1993-06-01

This document describes activities for the closure of a surface impoundment (2101-M Pond) at the Hanford Site. The 2101-H Pond was initially constructed in 1953 to serve as a drainage collection area for the 2101-H Building. (Until the Basalt Waste Isolation Project (BWIP) Laboratory was constructed in the 2101-M Building in 1979--1981, the only source contributing discharge to the pond was condensate water from the 2101-H Building heating, ventilation, and air conditioning (HVAC) system. The drains for the BWIP Laboratory rooms were plumbed into a 4-in., cast-iron, low-pressure drain pipe that carries waste water from the HVAC system to the pond. During the active life of the BWIP Laboratory, solutions of dissolved barium in groundwater samples were discharged to the 2101-M Pond via the laboratory drains. As a result of the discharges, a Part A permit application was initially submitted to the Washington State Department of Ecology (Ecology) in August 1986 which designates the 2101-M Pond as a surface impoundment

A hydrochemical data base for the Hanford Site, Washington

International Nuclear Information System (INIS)

Early, T.O.; Mudd, R.D.; Spice, G.D.; Starr, D.L.

1985-02-01

This data package contains a complete listing of the Site Hydrochemical Data Base for water samples associated with the Basalt Waste Isolation Project (BWIP). In addition to the detailed chemical analyses are a summary description of the data base format, detailed descriptions of verification procedures used to check data entries, and detailed descriptions of validation procedures used to evaluate data quality

Evaluation of alternative spent fuel waste package concepts for a repository in Basalt

International Nuclear Information System (INIS)

Hall, G.V.B.; Nair, B.R.

1986-01-01

The United States government has established a program for the disposal of spent nuclear fuel and high-level radioactive waste. The Nuclear Waste Policy Act (NWPA) of 1982 requires the first nuclear waste repository to begin receiving high-level radioactive waste in 1998. One of the potentially acceptable sites currently being evaluated is the Hanford Site in the Pasco Basin in the state of Washington where the host rock is basalt. Under the direction of the United States Department of Energy (DOE), Rockwell International's Rockwell Hanford Operations (RHO) has initiated the Basalt Waste Isolation Project (BWIP). The BWIP must design waste packages for emplacement in the repository. As part of the BWIP waste package development program, several alternative designs were considered for the disposal of spent nuclear fuel. This paper describes the concepts that were evaluated, the criteria that was developed for judging their relative merits, and the methodology that was employed. The results of the evaluation show that a Pipe-In-Tunnel design, which uses a long carbon steel pipe for the containment barrier for multiple packages of consolidated spent fuel, has the highest rating. Other designs which had high ratings are also discussed

Design and installation of deep multilevel piezometer nests in Columbia River basalts at the Hanford Site, Washington

International Nuclear Information System (INIS)

Jackson, R.L.; Veatch, M.D.

1985-04-01

The Basalt Waste Isolation Project (BWIP) was established in 1976 as part of the National Waste Terminal Storage Program, now the Office of Civilian Radioactive Waste Management. The BWIP objective is to assess the suitability of basalt as a repository medium for the long-term storage of commercial high-level radioactive waste. As part of the hydrogeologic characterization activities, BWIP designed and installed multilevel piezometer nests at three borehole cluster sites within and adjacent to the 18-square-mile reference repository location. These borehole cluster sites will provide multilevel piezometric baseline data across the reference repository location prior to, during, and after drilling a large-diameter exploratory shaft. They will also be used to monitor future hydraulic stress tests on a large scale. Three series of piezometer nests (A-, C-, and D-series) were installed at three borehole cluster sites in nine hydrogeologic units from a depth of about 500 to 3700 feet within the Columbia River Basalt Group. These multilevel monitoring zones are isolated from each other and the next overlying hydrogeologic unit by high-density cement seals. The A-series piezometer nests monitor two shallow sedimentary units. The C-series piezometer nests monitor basalt flow tops in the six deepest zones. The D-series piezometer monitors an intermediate sedimentary unit. Each piezometer tube was developed by air-lift pumping to complete the installtion prior to installing downhole pressure transducers. 23 refs., 10 figs., 1 tab

Hanford and the tri-cities economy: Review and outlook, March 1989

International Nuclear Information System (INIS)

Scott, M.J.; Belzer, D.B.; March, S.J.; Beck, D.M.; Schultz, R.W.; Harkreader, S.A.

1989-03-01

The economy of the Tri-Cities, Washington area (primarily, Benton and Franklin Counties) is in transition due to major changes in two Department of Energy programs at Hanford---the abrupt ending of the Basalt Waste Isolation Project (BWIP) in December 1987 and the placing of the N Reactor in ''cold standby'' status in February 1988. This report reviews the economic situation in the Tri-Cities during 1988 and presents forecasts for key economic indicators for 1989. This report will be updated about every six months to review the changes in the area economy and forecast the near-term outlook. 6 figs., 33 tabs

Hanford and the tri-cities economy: Review and outlook, March 1989

Energy Technology Data Exchange (ETDEWEB)

Scott, M.J.; Belzer, D.B.; March, S.J.; Beck, D.M.; Schultz, R.W.; Harkreader, S.A.

1989-03-01

The economy of the Tri-Cities, Washington area (primarily, Benton and Franklin Counties) is in transition due to major changes in two Department of Energy programs at Hanford---the abrupt ending of the Basalt Waste Isolation Project (BWIP) in December 1987 and the placing of the N Reactor in ''cold standby'' status in February 1988. This report reviews the economic situation in the Tri-Cities during 1988 and presents forecasts for key economic indicators for 1989. This report will be updated about every six months to review the changes in the area economy and forecast the near-term outlook. 6 figs., 33 tabs.

A compilation of subsurface hydrogeologic data

International Nuclear Information System (INIS)

1986-03-01

This volume contains a continuation of the fracture data for the research sites discussed in Volume 1 which have been studied in sufficient detail to allow for analysis. The sites discussed in this volume are the following: Climax Granite Nevada Test Site; OCRD Room, Colorado School of Mines; Savannah River Plant, Aiken, South Carolina; Oracle, Arizona; Basalt Waste Isolation Project (BWIP), Hanford, Washington Underground Research Laboratory, AECL, Canada; Atikokan Research Area, AECL; Chalk River Research Area, AECL; Whiteshell Research Area, AECL. Other sources of information have been included where sufficient site specific geologic and hydrogeologic information is provided

Session II-D. Systems

International Nuclear Information System (INIS)

Hall, R.J.

1981-01-01

The objectives of the Systems Task in the NWTS Program include: development of program requirements, allocation of the requirements to subsystems or tasks, integration of the task activities towards meeting the overall requirements, and assessment of progress towards achievement of the program mission. The Systems Task also includes a number of ancillary activities which are necessary to the program but which do not logically fall into other work-breakdown structure elements. Activities in the Systems Task, which in the NWTS Program are conducted at both the program and project levels, are generally grouped under the heading systems engineering and include identification of requirements, development of a baseline, integration of the system, baseline control, functional analyses, trade-off studies, and system analyses. The following papers in this session address some of the activities and progress that was achieved in the Systems Task in FY 1981: (1) waste isolation system alternatives: a cost comparison; (2) BWIP technical integration and control; (3) BWIP performance evaluation process: a criteria based method; (4) impacts of waste age; (5) systems studies of subseabed disposal; and (6) systems studies of waste transportation

Evaluation of DOE radionuclide solubility data and selected retardation parameters: description of calculational and confirmatory experimental activities

International Nuclear Information System (INIS)

Kelmers, A.D.; Clark, R.J.; Cutshall, N.H.; Johnson, J.S.; Kessler, J.H.

1983-01-01

An experimentally oriented program has been initiated to support the NRC analysis and licensing activities related to high-level nuclear waste repositories. The program will allow the NRC to independently confirm key geochemical values used in the site performance assessments submitted by the DOE candidate repository site projects. Key radionuclide retardation factor values, particularly radionuclide solubility and sorption values under site specific geochemical conditions, are being confirmed. The initial efforts are being directed toward basalt rock/groundwater systems relevant to the BWIP candidate site in the Pasco Basin. Future work will consider tuff (NNWSI candidate site in Yucca Mountain) and salt (unspecified ONWI bedded or domal salt sites) rock/groundwater systems. Initial experimental results with technetium have confirmed the BWIP values for basalt/groundwater systems under oxic redox conditions: high solubility and no sorption. Under reducing redox conditions, however, the experimental work did not confirm the proposed technetium values recommended by BWIP. In the presence of hydrazine to establish reducing conditions, an apparent solubility limit for technetium of about 5E-7 mol/L was encountered; BWIP recommended calculated values of 1E-12 or greater than or equal to 1E-14 mol/L. Experimental evidence concerning sorption of reduced technetium species is incomplete at this time. Equilibrium speciation and saturation indices were calculated for well water data sets from BWIP using the computer code PHREEQUE. Oversaturation was indicated for hematite and quartz in all data sets. Near surface samples were undersaturated with respect to calcite, but most deep samples were oversaturated with respect to calcite and other carbonate minerals

Socioeconomic conditions in cultural communities: The Nez Perce Tribe, the confederated Tribes of the Umatilla Indian Reservation and the confederated tribes and bands of the Yakima Indian Nation: Interim profile report

International Nuclear Information System (INIS)

Stokowski, P.A.; Friedli, E.A.

1987-11-01

A series of BWIP Socioeconomic Profile Reports are being prepared. This report is one of the first set of five separate BWIP Profile Reports, which cover: economic/demographic conditions; fiscal conditions; housing characteristics; public services and facilities; and socioeconomic conditions in cultural communities. The BWIP Socioeconomic Profile Reports are designed to provide information about the characteristics of the communities in which socioeconomic impacts from BWIP may occur. The Profile Reports present a compilation of historical information about socioeconomic conditions in the affected communities. These reports are designed to provide a transition between the BWIP EA, published in 1986, the Monitoring Reports, and other technical reports associated with the BWIP SMMP and CSP. The principal objectives of the Profile Reports are to update the DOE BWIP socioeconomic database by compiling available secondary and primary data and to make this information available to both the DOE program and other interested parties. The initial Profile Reports will help identify the need for additional data. The database developed for the profiles will assemble socioeconomic data in a uniform, readily accessible format. 16 refs., 1 fig., 17 tabs

A compilation of subsurface hydrogeologic data

International Nuclear Information System (INIS)

1986-03-01

This volume contains the permeability data for the research sites discussed in Volume 1 which have been studied in sufficient detail to allow for analysis. These sites are the following: Stripa Mine, Sweden; Finnsjon, Kamlunge, Fjallveden, Gidea, Svartboberget, Sweden; Olkiluoto, Loviisa, Lavia, Finland; Climax Granite Nevada Test Site; OCRD Room, Colorado School of Mines; Savannah River Plant, Aiken, South Carolina; Oracle, Arizona; Basalt Waste Isolation Project (BWIP), Hanford, Washington; Underground Research Laboratory, AECL, Canada; Atikokan Research Area, AECL; Chalk River Research Area, AECL; Whiteshell Research Area, AECL. Other sources of information have been included where sufficient site specific geologic and hydrogeologic information is provided

Site identification presentation: Basalt Waste Isolation Project

International Nuclear Information System (INIS)

1979-11-01

The final step in the site identification process for the Basalt Waste Isolation Project is described. The candidate sites are identified. The site identification methodology is presented. The general objectives which must be met in selecting the final site are listed. Considerations used in the screening process are also listed. Summary tables of the guidelines used are included

Seismic isolation of lead-cooled reactors: The European project SILER

International Nuclear Information System (INIS)

Forni, Massimo; Poggianti, Alessandro; Scipinotti, Riccardo; Dusi, Alberto; Manzoni, Elena

2014-01-01

SILER (Seismic-Initiated event risk mitigation in LEad-cooled Reactors) is a Collaborative Project, partially funded by the European Commission in the 7th Framework Programme, aimed at studying the risk associated to seismic-initiated events in Generation IV Heavy Liquid Metal reactors, and developing adequate protection measures. The project started in October 2011, and will run for a duration of three years. The attention of SILER is focused on the evaluation of the effects of earthquakes, with particular regards to beyond-design seismic events, and to the identification of mitigation strategies, acting both on structures and components design. Special efforts are devoted to the development of seismic isolation devices and related interface components. Two reference designs, at the state of development available at the beginning of the project and coming from the 6th Programme, have been considered: ELSY (European Lead Fast Reactor) for the Lead Fast Reactors (LFR), and MYRRHA (Multi-purpose hYbrid Research Reactor for High-tech Applications) for the Accelerator-Driven Systems (ADS). This paper describes the main activities and results obtained so far, paying particular attention to the development of seismic isolators, and the interface components which must be installed between the isolated reactor building and the non-isolated parts of the plant, such as the pipe expansion joints and the joint-cover of the seismic gap.

Subsurface geology of the Cold Creek syncline

International Nuclear Information System (INIS)

Meyers, C.W.; Price, S.M.

1981-07-01

Bedrock beneath the Hanford Site is being evaluated by the Basalt Waste Isolation Project (BWIP) for possible use by the US Department of Energy as a geologic repository for nuclear waste storage. Initial BWIP geologic and hydrologic studies served to determine that the central Hanford Site contains basalt flows with thick, dense interiors that have low porosities and permeabilities. Furthermore, within the Cold Creek syncline, these flows appear to be nearly flat lying across areas in excess of tens of square kilometers. Such flows have been identified as potential repository host rock candidates. The Umtanum flow, which lies from 900 to 1150 m beneath the surface, is currently considered the leading host rock candidate. Within the west-central Cold Creek syncline, a 47-km 2 area designated as the reference repository location (RRL) is currently considered the leading candidate site. The specific purpose of this report is to present current knowledge of stratigraphic, lithologic, and structural factors that directly relate to the suitability of the Umtanum flow within the Cold Creek syncline for use as a nuclear waste repository host rock. The BWIP geologic studies have concentrated on factors that might influence groundwater transport of radionuclides from this flow. These factors include: (1) intraflow structures within the interiors of individual lava flows, (2) interflow zones and flow fronts between adjacent lava flows, and (3) bedrock structures. Data have been obtained primarily through coring and geophysical logging of deep boreholes, petrographic, paleomagnetic, and chemical analysis, seismic-reflection, gravity, and magnetic (ground and multilevel airborne) surveys, and surface mapping. Results included in this document comprise baseline data which will be utilized to prepare a Site Characterization Report as specified by the US Nuclear Regulatory Commission

Basalt waste isolation project overview

International Nuclear Information System (INIS)

Dahlem, D.H.

1987-01-01

The proposed candidate site for a high-level nuclear waste repository is located beneath the Hanford Nuclear Reservation in southeastern Washington State. At this point, the Hanford Reservation has been selected as one of three preferred candidates in the draft environmental assessment. Project activities have concentrated on understanding the site location with respect to the 10CFR60, 40CFR191, and 10CFR960, identifying critical parameters for design of water package and repository seals, and identifying parameters for repository design. This paper describes the program to evaluate the site and to identify the natural processes that would effect isolation

BWIP [Battelle Waste Isolation Program] Repository Project: Interim fiscal profile, Benton and Franklin counties, Washington: Working draft

International Nuclear Information System (INIS)

Dong, F.B.; Dugan, M.K.; Clark, D.C.

1988-02-01

This report presents a fiscal profile of Benton and Franklin counties, and of the cities of Richland, Kennewick, and Pasco. Overall, changes in operating revenues and expenditures in these jurisdictions have corresponded with changes in the local economy. The combined operating expenditures of Benton County, Franklin County, Kennewick, Pasco, and Richland, expressed in current dollars, tripled between 1975 and 1985, increasing from $18.1 million to $55.0 million, an annual average increase of 11.8 percent. During this time, the population of the Benton-Franklin MSA increased from 100,000 to 140,900 people, and the national all-items price index for urban consumers doubled, increasing from 161.2 to 322.2. Adjusted for inflation, per capita expenditures by these governments increased only slightly during this period, from $361.8 in 1975 to $390.3 in 1985. Employment in the Benton-Franklin MSA rose from 40,080 workers in 1970 to a peak of 75,900 in 1981 before declining to 61,100 in 1985, primarily due to the loss of 9,928 jobs in the Washington Public Power Supply System after 1981. The MSA's population followed a similar trend, with a slight lag. In 1970, total population in the Benton-Franklin MSA was 93,356 people. The MSA's population grew rapidly during the late 1970s, reached a peak of 147,900 persons in 1982, and then declined to 139,300 in 1986. 23 refs., 16 figs., 14 tabs

Craniofacial morphology in unoperated infants with isolated cleft palate. A cephalometric analysis in three projections

DEFF Research Database (Denmark)

Hermann, N.V.; Kreiborg, S.; Jensen, B.L.

58th Annual Meeting of the American Cleft Palate-Craniofacial Association, Minneapolis, Craniofacial morphology, unoperated infants, isolated cleft palate, cephalometric analysis, three projections......58th Annual Meeting of the American Cleft Palate-Craniofacial Association, Minneapolis, Craniofacial morphology, unoperated infants, isolated cleft palate, cephalometric analysis, three projections...

A Seismic Isolation Application Using Rubber Bearings; Hangar Project in Turkey

International Nuclear Information System (INIS)

Sesigur, Haluk; Cili, Feridun

2008-01-01

Seismic isolation is an effective design strategy to mitigate the seismic hazard wherein the structure and its contents are protected from the damaging effects of an earthquake. This paper presents the Hangar Project in Sabiha Goekcen Airport which is located in Istanbul, Turkey. Seismic isolation system where the isolation layer arranged at the top of the columns is selected. The seismic hazard analysis, superstructure design, isolator design and testing were based on the Uniform Building Code (1997) and met all requirements of the Turkish Earthquake Code (2007). The substructure which has the steel vertical trusses on facades and RC H shaped columns in the middle axis of the building was designed with an R factor limited to 2.0 in accordance with Turkish Earthquake Code. In order to verify the effectiveness of the isolation system, nonlinear static and dynamic analyses are performed. The analysis revealed that isolated building has lower base shear (approximately 1/4) against the non-isolated structure

Basalt waste isolation project. Quarterly report, April 1, 1981-June 30, 1981

Energy Technology Data Exchange (ETDEWEB)

Deju, R.A.

1981-08-01

This document reports progress made in the Basalt Waste Isolation Project during the third quarter of fiscal year 1981. Efforts are described for the following programs of the project work breakdown structure: systems; waste package; site; repository; regulatory and institutional; test facilities; in situ test facilities.

Assessing social and economic effects of perceived risk: Workshop summary: Draft: BWIP Repository Project. [Basalt Waste Isolation Program

Energy Technology Data Exchange (ETDEWEB)

Nealey, S.M.; Liebow, E.B. (eds.)

1988-03-01

The US Department of Energy sponsored a one-day workshop to discuss the complex dimensions of risk judgment formation and the assessment of social and economic effects of risk perceptions related to the permanent underground storage of highly radioactive waste from commercial nuclear power plants. Affected parties have publicly expressed concerns about potentially significant risk-related effects of this approach to waste management. A selective review of relevant literature in psychology, decision analysis, economics, sociology, and anthropology was completed, along with an examination of decision analysis techniques that might assist in developing suitable responses to public risk-related concerns. The workshop was organized as a forum in which a set of distinguished experts could exchange ideas and observations about the problems of characterizing the effects of risk judgments. Out of the exchange emerged the issues or themes of problems with probabilistic risk assessment techniques are evident; differences exist in the way experts and laypersons view risk, and this leads to higher levels of public concern than experts feel are justified; experts, risk managers, and decision-makers sometimes err in assessing risk and in dealing with the public; credibility and trust are important contributing factors in the formation of risk judgments; social and economic consequences of perceived risk should be properly anticipated; improvements can be made in informing the public about risk; the role of the public in risk assessment, risk management and decisions about risk should be reconsidered; and mitigation and compensation are central to resolving conflicts arising from divergent risk judgments. 1 tab.

The project De Caldas International Project: An example of a large-scale radwaste isolation natural analogue study

International Nuclear Information System (INIS)

Shea, M.

1995-01-01

The proper isolation of radioactive waste is one of today's most pressing environmental issues. Research is being carried out by many countries around the world in order to answer critical and perplexing questions regarding the safe disposal of radioactive waste. Natural analogue studies are an increasingly important facet of this international research effort. The Pocos de Caldas Project represents a major effort of the international technical and scientific community towards addressing one of modern civilization's most critical environmental issues - radioactive waste isolation

FY-87 packing fabrication techniques (commercial waste form) results

International Nuclear Information System (INIS)

Werry, E.V.; Gates, T.E.; Cabbage, K.S.; Eklund, J.D.

1988-04-01

This report covers the investigation of fabrication techniques associated with the development of suitable materials and methods to provide a prefabricated packing for waste packages for the Basalt Waste Isolation Project (BWIP). The principal functions of the packing are to minimize container corrosion during the 300 to 1000 years following repository closure and provide long-term control of the release of radionuclides from the waste package. The investigative work, discussed in this report, was specifically conceived to develop the design criteria for production of full-scale prototypical packing rings. The investigative work included the preparation of procedures, the preparation of fabrication materials, physical properties, and the determination of the engineering properties. The principal activities were the preparation of the materials and the determination of the physical properties. 21 refs., 20 figs., 14 tabs

Anatomy of isolated monopole in Abelian projection od SU(2) lattice gauge theory

CERN Document Server

Belavin, V A; Veselov, A I

2001-01-01

The structure of the isolated static monopolies in the maximum Abelian projection of the SU(2) gluodynamics on the lattice studied. The standard parametrization of the coupling matrix was used by determining the maximum Abelian projection of the R functional maximization relative to all scale transformations. The monopole radius R approx = 0.06 fm is evaluated

Phenotypic and genotypic characterization of Thai isolates of Plasmodium falciparum after an artemisinin resistance containment project.

Science.gov (United States)

Thita, Thunyapit; Jadsri, Pimrat; Thamkhantho, Jarupatr; Ruang-Areerate, Toon; Suwandittakul, Nantana; Sitthichot, Naruemon; Mahotorn, Kittiya; Tan-Ariya, Peerapan; Mungthin, Mathirut

2018-05-15

In Thailand, artemisinin-based combination therapy (ACT) has been used to treat uncomplicated falciparum malaria since 1995. Unfortunately, artemisinin resistance has been reported from Thailand and other Southeast Asian countries since 2003. Malarone ® , a combination of atovaquone-proguanil (ATQ-PG), has been used to cease artemisinin pressure in some areas along Thai-Cambodia border, as part of an artemisinin resistance containment project since 2009. This study aimed to determine genotypes and phenotypes of Plasmodium falciparum isolates collected from the Thai-Cambodia border after the artemisinin resistance containment project compared with those collected before. One hundred and nine of P. falciparum isolates collected from Thai-Cambodia border from Chanthaburi and Trat provinces during 1988-2016 were used in this study. Of these, 58 isolates were collected after the containment. These parasite isolates were characterized for in vitro antimalarial sensitivities including chloroquine (CQ), quinine (QN), mefloquine (MQ), piperaquine (PPQ), artesunate (AS), dihydroartemisinin (DHA), ATQ and PG and genetic markers for drug resistance including the Kelch13 (k13), Plasmodium falciparum chloroquine resistance transporter (pfcrt), P. falciparum multidrug resistance 1 (pfmdr1) and cytochrome b (cytb) genes. Mean CQ, QN, MQ, PPQ and AS IC 50 s of the parasite isolates collected from 2009 to 2016 exhibited significantly higher than those of parasites collected before 2009. Approximately 57% exhibited in vitro MQ resistance. Approximately 94% of the isolates collected from 2009 to 2016 contained the pfmdr1 184F allele. Mutations of the k13 gene were detected in approximately 90% of the parasites collected from 2009 to 2016 which were significantly higher than the parasite isolates collected before. No ATQ-resistant genotype and phenotype of P. falciparum were found among the isolates collected after the containment project. Although the containment project had been

Devising a groundwater monitoring strategy for a geologic repository for radioactive waste

International Nuclear Information System (INIS)

Leonhart, L.S.; DeLuca, F.A.; Sheahan, N.T.; West, L.M.

1981-01-01

This paper represents a topical treatment of the subject of groundwater monitoring as it relates to the particular needs of high-level nuclear waste disposal facilities using the Basalt Waste Isolation Project (BWIP) as a specific reference. While the involvement with management of high-level radioactive wastes and the design and operation of repository facilities is presently parochial to the federal government and certain prime contractors, it is believed that the technical aspects involved with this groundwater monitoring example provide an interesting comparison with those encountered at near-surface and underground-injection, hazardous waste disposal operations. In particular, the integration of several program facets ranging from baselining parameters to validation of predictive models into a comprehensive strategy may be of interest. It is hoped that this type of conceptual exchange will be beneficial to all concerned

A compilation of subsurface hydrogeologic data

International Nuclear Information System (INIS)

1986-03-01

This volume contains the storage coefficient, porosity, compressibility and fracture data for the research sites discussed in Volume 1 which have been studied in sufficient detail to allow for analysis. These sites are the following: Stripa Mine, Sweden; Finnsjon, Kamlunge, Fjallveden, Gidea, Svartboberget, Sweden; Olkiluoto, Loviisa, Lavia, Finland; Climax Granite Nevada Test Site; OCRD Room, Colorado School of Mines; Savannah River Plant, Aiken, South Carolina; Oracle, Arizona; Basalt Waste Isolation Project (BWIP), Hanford, Washington; Underground Research Laboratory, AECL, Canada; Atikokan Research Area, AECL; Chalk River Research Area, AECL; Whiteshell Research Area, AECL. Other sources of information have been included where sufficient site specific geologic and hydrogeologic information is provided. The fracture data for the first three of the sites listed above are contained in this volume. The fracture data for the remaining research research sites are discussed in Volume 4

Draft site characterization analysis of the site characterization report for the Basalt Waste Isolation Project, Hanford, Washington site. Appendices E through W

International Nuclear Information System (INIS)

1983-03-01

Volume 2 contains Appendices E through W: potential for large-scale pump tests in the Grande Ronde; review of hydrochemical characterization related to flow system interpretation in Hanford basalts; limitations of packer-testing for head evaluation in Hanford basalts; hydrogeologic data integration for conceptual groundwater flow models; drilling mud effects on hydrogeologic testing; site issue analyses related to the nature at the present groundwater system at the Hanford site, Washington; structural and stratigraphic characteristics related to groundwater flow at the Hanford site, Washington; seismic hazard and some examples of hazard studies at Hanford; earthquake swarms in the Columbia Plateau; seismic ground motion at depth; failure modes for the metallic waste package component; degradation mechanisms of borosilicate glass; transport and retardation of radionuclides in the waste package; determination and interpretation of redox conditions and changes in underground high-level repositories; determination and interpretation of sorption data applied to radionuclide migration in underground repositories; solubility of radionuclide compounds presented in the BWIP site characterization report; and release rate from engineered system

The Waste Isolation Pilot Plant (WIPP) integrated project management system

International Nuclear Information System (INIS)

Olona, D.; Sala, D.

1993-01-01

The Waste Isolation Pilot Plant (WIPP), located 26 miles east of Carlsbad, New Mexico, is a research and development project of the Department of Energy (DOE), tasked with the mission of demonstrating the safe disposal of transuranic (TRU) radioactive wastes. This unique project was authorized by Congress in 1979 in response to the national need for long-term, safe methods for disposing of radioactive by-products from our national defense programs. The WIPP was originally established in December of 1979, by Public Law 96-164, DOE National Security and Military Applications of Nuclear Energy Authorization Act of 1980. Since the inception of the WIPP Project, work has continued to prepare the facility to receive TRU wastes. Studies continue to be conducted to demonstrate the safety of the WIPP facility in accordance with federal and state laws, state agreements, environmental regulations, and DOE Orders. The objectives of implementing an integrated project management system are to assure compliance with all regulatory and federal regulations, identify areas of concern, provide justification for funding, provide a management tool for control of program workscope, and establish a project baseline from which accountability and performance will be assessed. Program management and project controls are essential for the success of the WIPP Project. The WIPP has developed an integrated project management system to establish the process for the control of the program which has an expected total dollar value of $2B over the ten-year period from 1990-2000. The implementation of this project management system was motivated by the regulatory requirements of the project, the highly public environment in which the project takes place, limited funding and resources, and the dynamic nature of the project. Specific areas to be addressed in this paper include strategic planning, project organization, planning and scheduling, fiscal planning, and project monitoring and reporting

Isolated elders demonstration project : closer to home - a descriptive evaluation

OpenAIRE

Cusack, Sandra A.

1996-01-01

The purpose of this demonstration project is to support isolated elders through outreach. The goal is to get seniors "out of their homes" and back into the community, assisting them to make decisions and take action on their own behalf. The process involved training a group of volunteers to interview elders, using a mini-life review technique to encourage reminiscence. In listening to their stories, the volunteer's task was to discover the elder's needs and barriers to socialization, and to l...

Repository environmental parameters and models/methodologies relevant to assessing the performance of high-level waste packages in basalt, tuff, and salt

Energy Technology Data Exchange (ETDEWEB)

Claiborne, H.C.; Croff, A.G.; Griess, J.C.; Smith, F.J.

1987-09-01

This document provides specifications for models/methodologies that could be employed in determining postclosure repository environmental parameters relevant to the performance of high-level waste packages for the Basalt Waste Isolation Project (BWIP) at Richland, Washington, the tuff at Yucca Mountain by the Nevada Test Site, and the bedded salt in Deaf Smith County, Texas. Guidance is provided on the identify of the relevant repository environmental parameters; the models/methodologies employed to determine the parameters, and the input data base for the models/methodologies. Supporting studies included are an analysis of potential waste package failure modes leading to identification of the relevant repository environmental parameters, an evaluation of the credible range of the repository environmental parameters, and a summary of the review of existing models/methodologies currently employed in determining repository environmental parameters relevant to waste package performance. 327 refs., 26 figs., 19 tabs.

Repository environmental parameters and models/methodologies relevant to assessing the performance of high-level waste packages in basalt, tuff, and salt

International Nuclear Information System (INIS)

Claiborne, H.C.; Croff, A.G.; Griess, J.C.; Smith, F.J.

1987-09-01

This document provides specifications for models/methodologies that could be employed in determining postclosure repository environmental parameters relevant to the performance of high-level waste packages for the Basalt Waste Isolation Project (BWIP) at Richland, Washington, the tuff at Yucca Mountain by the Nevada Test Site, and the bedded salt in Deaf Smith County, Texas. Guidance is provided on the identify of the relevant repository environmental parameters; the models/methodologies employed to determine the parameters, and the input data base for the models/methodologies. Supporting studies included are an analysis of potential waste package failure modes leading to identification of the relevant repository environmental parameters, an evaluation of the credible range of the repository environmental parameters, and a summary of the review of existing models/methodologies currently employed in determining repository environmental parameters relevant to waste package performance. 327 refs., 26 figs., 19 tabs

The waste isolation pilot plant project: a changing paradigm

International Nuclear Information System (INIS)

Sheppard, L.E.; McFadden, M.H.

1996-01-01

The Waste Isolation Pilot Plant (WIPP) is a US Department of Energy (DOE) repository that has been developed to demonstrate the safe and permanent isolation of transuranic radioactive wastes in a deep geologic site. It is located in 650 m below the surface in a bedded salt formation, and is designed to hold approximately 175,500 cubic meters of waste. Compliance with the regulations has become the principal focus for the Project. The scientific baseline is an important and integral part of the CCA, as it provides the foundation for conducting total system performance assessment calculations for comparison with applicable standards. The activities required to support the scientific baseline are being pursued in parallel to minimize the time required to collect, analyze, interpret and fully incorporate the results into the CCA. The DOE has shifted its approach to demonstrating compliance with the applicable regulations from a paradigm of a series of broad investigations to a new paradigm of highly focused activities conducted in parallel. The success of this approach will be assessed by the EPA when the application is critically reviewed

DOE progress in assessing the long term performance of waste package materials

International Nuclear Information System (INIS)

Berusch, A.; Gause, E.

1987-01-01

Under the Nuclear Waste Policy Act of 1982 (NWPA)[1], the US Dept. of Energy (DOE) is conducting activities to select and characterize candidate sites suitable for the construction and operation of a geologic repository for the disposal of high-level nuclear wastes. DOE is funding three first repository projects: Basalt Waste Isolation Project, BWIP; Nevada Nuclear Waste Isolation Project, NNWSI; and Salt Repository Project Office, SRPO. It is essential in the licensing process that DOE demonstrate to the NRC that the long-term performance of the materials and design will be in compliance with the requirements of 10 CFR 60.113 on substantially complete containment within the waste packages for 300 to 1000 years and a controlled release rate from the engineered barrier system (EBS) for 10,000 years of 1 part in 10 5 per year for radionuclides present in defined quantities 100 years after permanent closure. Obviously, the time spans involved make it impractical to base the assessment of the long term performance of waste package materials on real time, prototypical testing. The assessment of performance will be implemented by the use of models that are supported by real time field and laboratory tests, monitoring, and natural analog studies. Each of the repository projects is developing a plan for demonstrating long-term waste package material performance depending on the particular materials and the package-perturbed, time-dependent environment under which the materials must function. An overview of progress in each of these activities for each of the projects is provided in the following

Productivity, mortality, and response to disturbance of nesting Swainson's hawks on the Hanford Site

Energy Technology Data Exchange (ETDEWEB)

Poole, L.D.; Marr, N.V.; McCorquodale, S.M.

1988-03-01

The objectives of this study were to characterize Swainson's hawk (Buteo swainson) use of the US Department of Energy (DOE) Hanford Site and to evaluate the potential for engineering and other human activities on the Hanford Site to negatively affect the nesting Swainson's hawk population. Activities associated with the Basalt Waste Isolation Project (BWIP) were used as the primary external stimuli in studying hawk responses to potential human disturbance. Parked and moving vehicles were the most common disturbance sources observed in Swainson's hawk territories. Hawks appeared to be sensitive to disturbance from pedestrians and slow-moving vehicles near nests. Novel stimuli were much more likely to evoke strong responses than were recurring events. Adult hawks reacted more frequently and vigorously than did juveniles. When disturbed, adult hawks usually flew toward the location of the disturbance; juvenile hawks usually flew away from disturbances. Human activity associated with BWIP may have had negative on one pair of nesting Swainson's hawks and may have precluded the use of an additional traditional nesting territory. Negative impacts to nesting Swainson's hawks from human activity could be minimized by confining activities to the non-nesting period or to distances greater than 2.2 km from nest sites. Tree groves and elevated perches, including utility poles, across the Hanford Site are probably critical to the success of nesting Swainson's hawks. Potential mitigation strategies associated with energy research and development activities on the Hanford Site could include provisions for maintenance and establishment of drought-tolerant trees and native vegetation. 22 refs., 5 figs., 3 tabs.

A synthesis of ethnohistorical materials concerning the administration of Federal Indian policy among the Yakima, Umatilla, and Nez Perce Indian people: Working draft

International Nuclear Information System (INIS)

Liebow, E.B.; Younger, C.A.; Broyles, J.A.

1987-11-01

For the purposes of the Nuclear Waste Policy Act, the Confederated Tribes and Bands of the Yakima Indian Nation, the Confederated Tribes of the Umatilla Indian Reservation, and the Nez Perce Tribe have been accorded the status of ''Affected Indian Tribe'' and have become party to the proceedings to determine a suitable location for the nation's first commercial waste repository. Each of the Tribes has expressed concerns about the suitability of the Hanford Site in eastern Washington. These concerns, in general, address the proposed repository's effects on traditional spiritual beliefs and cultural practices, on tribal sovereignty and the Tribes' right to self-government, on the natural resources under tribal management jurisdiction, and on the health and socioeconomic characteristics of the Tribes' reservation communities. The Yakima, Umatilla, and Nez Perce have distinctive cultural traditions that may be adversely affected by activities related to the Basalt Waste Isolation Project (BWIP). Further, the Tribes enjoy a unique relationship with the federal government. Because of their distinctive cultures and governmental status, particular attention will be paid to expressed interests of the Tribes, and to ways in which these interests may be affected by the repository program. Monitoring is needed to describe current conditions among the Affected Tribes' populations, to describe BWIP site characterization activities affecting the Tribes, and to measure any changes in these conditions that may occur as a direct result of site characterization. This paper reports our first efforts at gathering historical information. It summarizes materials contained in two sources: the reports of field agents to the Commissioner of Indian Affairs (1854-1936), and the dockets of the Indian Claims Commission. 24 refs., 3 figs

Report on geologic exploration activities

International Nuclear Information System (INIS)

Breslin, J.; Laughon, R.B.; Hall, R.J.; Voss, J.W.

1980-01-01

This report provides an overview of the geological exploration activities being carried out as part of the National Waste Terminal Storage (NWTS) Program, which has been established by the US Department of Energy (DOE) to develop the technology and provide the facilities for the safe, environmentally acceptable isolation of civilian high-level and transuranic nuclear wastes, including spent fuel elements, for which the Federal government is responsible. The principal programmatic emphasis is on disposal in mined geologic repositories. Explorations are being conducted or planned in various parts of the country to identify potential sites for such repositories. The work is being undertaken by three separate but coordinated NWTS project elements. Under the Basalt Waste Isolation Project (BWIP), basalt formations underlying DOE's Hanford Reservation are being investigated. Granite, tuff, and shale formations at the DOE Nevada Test Site (NTS) are being similarly studied in the Nevada Nuclear Waste Storage Investigations (NNWSI). The Office of Nuclear Waste Isolation (ONWI) is investigating domed salt formations in several Gulf Coast states and bedded salt formations in Utah and Texas. The ONWI siting studies are being expanded to include areas overlying crystalline rocks, shales, and other geohydrologic systems. The current status of these NWTS efforts, including the projected budgets for FY 1981, is summarized, and the criteria and methodology being employed in the explorations are described. The consistency of the overall effort with the recommendations presented in the Report to the President by the Interagency Review Group on Nuclear Waste Management (IRG), as well as with documents representing the national technical consensus, is discussed

Report on geologic exploration activities

International Nuclear Information System (INIS)

1980-01-01

This report provides an overview of the geological exploration activities being carried out as part of the National Waste Terminal Storage (NWTS) Program, which has been established by the US Department of Energy (DOE) to develop the technology and provide the facilities for the safe, environmentally acceptable isolation of civilian high-level and transuranic nuclear wastes, including spent fuel elements, for which the Federal government is reponsible. The principal programmatic emphasis is on disposal in mined geologic repositories. Explorations are being conducted or planned in various parts of the country to identify potential sites for such repositories. The work is being undertaken by three separate but coordinated NWTS project elements. Under the Basalt Waste Isolation Project (BWIP), basalt formations underlying DOE's Hanford Reservation are being investigated. Granite, tuff, and shale formations at the DOE Nevada Test Site (NTS) are being similarly studied in the Nevada Nuclear Waste Storage Investigations (NNWSI). The Office of Nuclear Waste Isolation (ONWI) is investigating domed salt formations in several Gulf Coast states and bedded salt formations in Utah and Texas. Th ONWI siting studies are being expanded to include areas overlying crystalline rocks, shales, and other geohydrologic systems. The current status of these NWTS efforts, including the projected budgets for FY 1981, is summarized, and the criteria and methodology being employed in the explorations are described. The consistency of the overall effort with the recommendations presented in the Report to the President by the Interagency Review Group on Nuclear Waste Management (IRG), as well as with documents representing the national technical consensus, is discussed

The evolution of the Waste Isolation Pilot Plant (WIPP) project's public affairs program

International Nuclear Information System (INIS)

Walter, L.H.

1988-01-01

As a first-of-a-kind facility, the Waste Isolation Pilot Plant (WIPP) presents a unique perspective on the value of designing a public affairs program that grown with and complements a project's evolution from construction to operations. Like the project itself, the public affairs programs progressed through several stages to its present scope. During the construction phase, foundations were laid in the community. Then, in this past year as the project entered a preoperational status, emphasis shifted to broaden the positive image that had been created locally. In this stage, public affairs presented the project's positive elements to the various state agencies, government officials, and federal organizations involved in our country's radioactive waste management program. Most recently, and continuing until receipt of the first shipment of waste in October 1988, an even broader, more aggressive public affairs program is planned

Performance allocation traceable to regulatory criteria as applied to site characterization work at the Basalt Waste Isolation Project

International Nuclear Information System (INIS)

Deju, R.A.; Babad, H.; Bensky, M.S.; Jacobs, G.K.

1983-01-01

The Basalt Waste Isolation Project has developed a method for defining in detail the work required to demonstrate the feasibility of emplacing and providing for the safe isolation of nuclear wastes in a repository in the deep basalts at the Hanford Site near Richland, Washington. Criteria analysis allows the identification of areas of significant technical uncertainty or controversy that can be highlighted as issues. A preliminary analysis has been conducted, which, by identifying key radionuclides and allocating performance among the multiple barriers in a repository constructed in a basalt, allows the design and development testing activities at the Basalt Waste Isolation Project to be put into perspective. Application of sophisticated uncertainty analysis techniques will allow refinements in the analysis to be made and to further guide characterization and testing activities. Preliminary results suggest that a repository constructed in basalt will provide for the safe isolation of nuclear wastes in a cost-effective and reliable manner with a high degree of confidence

Developments in the monitoring and control of Eh and pH conditions in hydrothermal experiments

International Nuclear Information System (INIS)

Myers, J.; Ulmer, G.C.; Grandstaff, D.E.; Brozdowski, R.; Danielson, M.J.; Koski, O.H.

1984-01-01

In the design of a high-level nuclear waste repository it is essential to obtain accurate groundwater Eh-pH data. Design considerations such as the choice of matrix for the waste form, type and dimensions of canister material, use of buffers, and type and amount of backfill would all benefit from an exact knowledge of oxidation potentials (Eh) and acidity levels (pH) of the groundwater. The Basalt Waste Isolation Project (BWIP) has initiated a research effort to develop sensors which can be mounted in autoclaves to provide constant monitoring of the Eh-pH conditions that exist during waste form/barrier material/groundwater hydrothermal interaction tests. Sensors must withstand temperatures up to 300 0 C and pressures up to 300 bars. This report considers Teflon hydrogen diffusion membranes and zirconia pH sensors. The development of these sensors represents a significant advance in the environmental monitoring of Eh and pH conditions at elevated temperatures and pressures

Commercial nuclear waste repository in basalt

International Nuclear Information System (INIS)

Hardy, M.P.; Patricio, J.G.; Heley, W.H.

1980-06-01

The Basalt Waste Isolation Project (BWIP) is an ongoing research and engineering effort being conducted by Rockwell Hanford Operations (Rockwell), which is under contract to the US Department of Energy. The objectives of this program are to assess the feasibility of and to provide the technology needed to design and construct a licensed commercial nuclear waste repository in the deep basalt formations underlying the Hanford Site. An extensive preconceptual design effort was undertaken during 1979 to develop a feasible concept that could serve as a reference design for both surface and underground facilities. The preconceptual design utilized existing technology to the greatest extent possible to offer a system design that could be utilized in establishing schedule and cost baseline data, recommend alternatives that require additional study, and develop basic design requirements that would allow evolution of the design process prior to the existence of legislated criteria. This paper provides a description of the concept developed for the subsurface aspects of this nuclear waste repository

Overview of the waste/barrier/rock interactions program of the basalt waste isolation project

International Nuclear Information System (INIS)

Salter, P.F.; Burnell, J.R.; Lane, D.L.

1986-01-01

The waste package waste/barrier/rock interactions testing program of the Basalt Waste Isolation Project is designed to assess the interactions between nuclear waste forms, other waste package components, and the environment in order to evaluate long-term waste package isolation (radionuclide release) behavior. The program involves reacting fully radioactive waste forms with combinations of steel or copper container material and basalt/bentonite packing material in site-specific ground water under anticipated repository conditions to obtain the steady state radionuclide concentrations required to predictively model waste package radionuclide concentrations required to predictively model waste package radionuclide releases. Both static and flow-through autoclaves are being used in the test program to determine radionuclide concentrations as a function of time and groundwater flow rate, and to evaluate the solid phase and water chemistry changes that control those concentrations. This test program, when combined with project hydrologic and geochemical testing and modeling efforts, and natural analog studies, provides the information required to evaluate long-term radionuclide mobility within a waste package emplaced in a basalt repository

Coupled geomechanical/hydrological modeling: an overview of basalt waste isolation project studies

International Nuclear Information System (INIS)

Baca, R.G.; Case, J.B.; Patricio, J.G.

1980-07-01

Basalt Waste Isolation Project investigations of the Columbia River basalts are multi-disciplinary in nature with a broad scope spanning such areas as geology, seismology, geochemistry, hydrology, rock mechanics, and many other disciplines as well. In this paper, an overview is presented which surveys recent work on numerical modeling of geomechanical and hydrological processes in a basalt rock environment. A major objective of the ongoing numerical modeling work is to establish a predictive technology base with which to: interpret the interrelationships between geomechanical behavior of rock media, the natural hydrologic phenomena, and repository conditions; evaluate the effectiveness of preconceptual repository designs and assist in the design of in situ field testing; and assess the waste isolation capability of candidate host rocks within the Columbia River basalts. To accomplish this objective, a systems approach has been adopted which is based on the use of digital simulation models

The development of the Waste Isolation Pilot Plant (WIPP) project's public affairs program

International Nuclear Information System (INIS)

Walter, L.H.

1988-01-01

The Waste Isolation Pilot Plant (WIPP) offers a perspective on the value of designing flexibility into a public affairs program to enable it to grow with and complement a project's evolution from construction through to operations. This paper discusses how the WIPP public affairs program progressed through several stages to its present scope. During the WIPP construction phase, the public affairs program laid a foundation for Project acceptance in the community. A speaker's bureau, a visitors program, and various community outreach and support programs emphasized the educational and socioeconomic benefits of having this controversial project in Carlsbad. Then, in this past year as the project entered a preoperational status, the public affairs program emphasis shifted to broaden the positive image that had been created locally. In this stage, the program promoted the project's positive elements with the various state agencies, government officials, and federal organizations involved in our country's radioactive waste management and transportation program. Currently, an even broader, more aggressive public affairs program is planned. During this stage public affairs will be engaged in a comprehensive institutional and outreach program, explaining and supporting WIPP's mission in each of the communities and agencies affected by the operation of the country's first geologic repository

Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 2. Commercial waste forms, packaging and projections for preconceptual repository design studies

International Nuclear Information System (INIS)

1978-04-01

This volume, Y/OWI/TM-36/2, ''Commercial Waste Forms, Packaging and Projections for Preconceptual Repository Design Studies,'' is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This volume contains the data base for waste forms, packages, and projections from the commercial waste defined by the Office of Waste Isolation in ''Nuclear Waste Projections and Source Term Data for FY 1977,'' Y/OWI/TM-34. Also, as an alternative data base for repository design and analysis, waste forms, packages, and projections for commercial waste defined by Battelle Pacific Northwest Laboratory (BPNL) have been included. This data base consists of a reference case for use in the alternative design study and a definition of combustible wastes for use in mine fire and hydrogen generation analyses

Basalt Waste Isolation Project. Annual report, fiscal year 1980

International Nuclear Information System (INIS)

1980-11-01

During this fiscal year the information available in the fields of geology and hydrology of the Columbia Plateau was consolidated and two reports were issued summarizing this information. In addition, the information on engineered barriers was consolidated and a report summarizing the research to date on waste package development and design of borehole seals was prepared. The waste package studies, when combined with the hydrologic integration, revealed that even under extreme disruptive conditions, a repository in basalt with appropriately designed waste packages can serve as an excellent barrier for containment of radionuclides for the long periods of time required for waste isolation. On July 1, 1980, the first two heater tests at the Near-Surface Test Facility were started and have been successfully operated to this date. The papers on the Near-Surface Test Facility section of this report present the results of the equipment installed and the preliminary results of the testing. In October 1979, the US Department of Energy selected the joint venture of Kaiser Engineers/Parsons Brinckerhoff Quade and Douglas, Inc., to be the architect-engineer to produce a conceptual design of a repository in basalt. During the year, this design has progressed and concept selection has now been completed. This annual report presents a summary of the highlights of the work completed during fiscal year 1980. It is intended to supplement and summarize the nearly 200 papers and reports that have been distributed to date as a part of the Basalt Waste Isolation Project studies

Status of initial phase of site-specific seismic monitoring: Basalt Waste Isolation Project

International Nuclear Information System (INIS)

Rohay, A.C.

1981-01-01

This report presents the status of the initial phase of site-specific seismic monitoring work conducted under the Basalt Waste Isolation Project. This work is currently organized under two main elements: (1) a portable array; and (2) a baseline data collection array. Progress toward the development of each array is discussed along with an interpretation of preliminary data obtained from the test of a borehole seismometer at potential repository depths. The text is supplemented by nine figures and one table. 9 figs., 1 tab

Hydrologic studies within the Pasco Basin

International Nuclear Information System (INIS)

Spane, F.A. Jr.

1982-09-01

As part of the Basalt Waste Isolation Project (BWIP), hydrologic studies are being performed to provide an evaluation of groundwater systems within the Columbia River Basalt Group. These studies are focused on the Hanford Site, which is located within the Pasco Basin in south-central Washington. Hydrologic studies within the Pasco Basin involve the areal and vertical characterization of hydraulic head, hydrologic properties, and hydrochemical content for the various basalt groundwater systems. Currently, in excess of 150 test intervals have been tested for hydraulic properties, while in excess of 80 horizons have been analyzed for hydrochemical characteristics at about 30 borehole sites within the Pasco Basin. Data obtained from these studies provide input for numerical modeling of groundwater flow and solute transport. Results from numerical modeling are used for evaluating potential waste migration as a function of space and time. In the Pasco Basin, geologic structures influence groundwater flow patterns within basalt aquifer systems. Potentiometric data and hydrochemical evidence collected from recent studies indicate that geologic structures act as areal hydrologic barriers and in some instances, regions of enhanced vertical conductivity. 8 figures

Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 2. Commercial waste forms, packaging and projections for preconceptual repository design studies

Energy Technology Data Exchange (ETDEWEB)

1978-04-01

This volume, Y/OWI/TM-36/2, ''Commercial Waste Forms, Packaging and Projections for Preconceptual Repository Design Studies,'' is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This volume contains the data base for waste forms, packages, and projections from the commercial waste defined by the Office of Waste Isolation in ''Nuclear Waste Projections and Source Term Data for FY 1977,'' Y/OWI/TM-34. Also, as an alternative data base for repository design and analysis, waste forms, packages, and projections for commercial waste defined by Battelle Pacific Northwest Laboratory (BPNL) have been included. This data base consists of a reference case for use in the alternative design study and a definition of combustible wastes for use in mine fire and hydrogen generation analyses.

Draft site characterization analysis of the site characterization report for the Basalt Waste Isolation Project, Hanford, Washington Site. Main report and Appendices A through D

International Nuclear Information System (INIS)

1983-03-01

On November 12, 1982, the US Department of Energy submitted to the US Nuclear Regulatory Commission the Site Characterization Report for the Basalt Waste Isolation Project (DOE/RL 82-3). The Basalt Waste Isolation Project is located on DOE's Hanford Reservation in the State of Washington. NUREG-0960 contains the detailed analysis, by the NRC staff, of the site characterization report. Supporting technical material is contained in Appendices A through W

Grouts and concretes for the Waste Isolation Pilot Project (WIPP)

International Nuclear Information System (INIS)

Wakeley, L.D.

1990-01-01

The Structures Laboratory of the U.S. Army Engineer Waterways Experiment Station has conducted research on cement-based composites for the Waste Isolation Pilot Project (WIPP) since 1977, in cooperation with Sandia National Laboratories. Field testing requirements guided initial development of grouts. Concurrent and later laboratory studies explored the chemical stability and probable durability of these mixtures. Beginning in 1985, a series of small-scale seal performance tests at the WIPP prompted development of an expansive salt-saturated concrete. Important lessons learned from this ongoing work include: (1) carefully tailored mixtures can tolerate phase changes involving Ca, Al, and SO 4 , without loss of structural integrity; (2) handling and placement properties are probably more crucial to the mixtures than is exact phase composition; and (3) for the environment of a geologic repository, demonstrated chemical durability will be the best indicator of long-term performance

Isolated systems with wind power. Main report

DEFF Research Database (Denmark)

Lundsager, P.; Bindner, Henrik W.; Clausen, Niels-Erik

2001-01-01

The overall objective of this research project is to study the development of methods and guidelines rather than "universal solutions" for the use of wind energy in isolated communities. The main specific objective of the project is to develop and present amore unified and generally applicable...... approach for assessing the technical and economical feasibility of isolated power supply systems with wind energy. As a part of the project the following tasks were carried out: Review of literature, fieldmeasurements in Egypt, development of an inventory of small isolated systems, overview of end...... for Isolated Systems with Wind Power, applicable for international organisations such as donoragencies and development banks....

Isolated systems with wind power. Main report

Energy Technology Data Exchange (ETDEWEB)

Lundsager, P.; Bindner, H.; Clausen, N.E.; Frandsen, S.; Hansen, L.H.; Hansen, J.C.

2001-06-01

The overall objective of this research project is to study the development of methods and guidelines rather than 'universal solutions' for the use of wind energy in isolated communities. The main specific objective of the project is to develop and present a more unified and generally applicable approach for assessing the technical and economical feasibility of isolated power supply systems with wind energy. As a part of the project the following tasks were carried out: Review of literature, field measurements in Egypt, development of an inventory of small isolated systems, overview of end-user demands, analysis of findings and development of proposed guidelines. The project is reported in one main report and four topical reports, all of them issued as Risoe reports. This is the Main Report Risoe-R-1256, summing up the activities and findings of the project and outlining an Implementation Strategy for Isolated Systems with Wind Power, applicable for international organisations such as donor agencies and development banks. (au)

Can we talk? Communications management for the Waste Isolation Pilot Plant, a complex nuclear waste management project

International Nuclear Information System (INIS)

Goldstein, S.A.; Pullen, G.M.; Brewer, D.R.

1995-01-01

Sandia Nuclear Waste Management Program is pursuing for DOE an option for permanently disposing radioactive waste in deep geologic repositories. Included in the Program are the Waste Isolation Pilot Plant (WIPP) Project for US defense program mixed waste the Yucca Mountain Project (YMP) for spent power reactor fuel and vitrified high-level waste, projects for other waste types, and development efforts in environmental decision support technologies. WIPP and YMP are in the public arena, of a controversial nature, and provide significant management challenges. Both projects have large project teams, multiple organization participants, large budgets, long durations, are very complex, have a high degree of programmatic risk, and operate in an extremely regulated environment requiring legal defensibility. For environmental projects like these to succeed, SNL's Program is utilizing nearly all areas in PMI's Project Management Body of Knowledge (PMBOK) to manage along multiple project dimensions such as the physical sciences (e.g., geophysics and geochemistry; performance assessment; decision analysis) management sciences (controlling the triple constraint of performance, cost and schedule), and social sciences (belief systems; public participation; institutional politics). This discussion focuses primarily on communication challenges active on WIPP. How is the WIPP team meeting the challenges of managing communications?'' and ''How are you approaching similar challenges?'' will be questions for a dialog with the audience

Systems

International Nuclear Information System (INIS)

Anon.

1980-01-01

Papers in this session describe the concept of mined geologic disposal system and methods for ensuring that the system, when developed, will meet all technical requirements. Also presented in the session are analyses of system parameters, such as cost and nuclear criticality potential, as well as a technical analysis of a requirement that the system permit retrieval of the waste for some period of time. The final paper discusses studies under way to investigate technical alternatives or complements to the mined geologic disposal system. Titles of the presented papers are: (1) Waste Isolation System; (2) Waste Isolation Economics; (3) BWIP Technical Baseline; (4) Criticality Considerations in Geologic Disposal of High-Level Waste; (5) Retrieving Nuclear Wastes from Repository; (6) NWTS Programs for the Evaluation of Technical Alternatives or Complements to Mined Geologic Repositories - Purpose and Objectives

Department of Energy Operation Quality Assurance Program for the Waste Isolation Pilot Plant (WIPP) Project (Carlsbad, New Mexico)

International Nuclear Information System (INIS)

1987-12-01

The purpose of this plan is to describe the Quality Assurance (QA)reverse arrow Program to be established and implemented by the US Department of Energy (DOE) Waste Isolation Pilot Plant (WIPP) Project Office (WPO) and by the Project Participants: the Scientific Advisor (Sandia National Laboratory) and the Management and Operating Contractor (Westinghouse Electric Corporation). This plan addresses the Pre-Operational and Operational phases of the WIPP Project not addressed under the construction phase. This plan also requires the QA Programs for DOE and Project Participants to be structured so as to comply with this plan and ANSI-ASME NQA-1. The prime responsibility for Operational Quality Assurance rests with the DOE WIPP Project Office and is implemented through the combined efforts of the Scientific Advisor and the Management and Operating Contractor. Overviews of selected operational and testing activities will be are conducted in accordance with prescribed requirements and that adequate documentation of these activities is maintained. 4 figs

Application of QA to R ampersand D support of HLW programs

International Nuclear Information System (INIS)

Ryder, D.E.

1988-01-01

Quality has always been of primary importance in the research and development (R ampersand D) environment. An organization's ability to attract funds for new or continued research is largely dependent on the quality of past performance. However, with the possible exceptions of peer reviews for fund allocation and the referee process prior to publication, past quality assurance (QA) activities were primarily informal good practices. This resulted in standards of acceptable practice that varied from organization to organization. The increasing complexity of R ampersand D projects and the increasing need for project results to be upheld outside the scientific community (i.e., lawsuits and licensing hearings) are encouraging R ampersand D organizations and their clients to adopt more formalized methods for the scientific process and to increase control over support organizations (i.e., suppliers and subcontractors). This has become especially true for R ampersand D organizations involved in the high-level (HLW) projects for a number of years. The PNL began to implement QA program requirements within a few HLW repository preliminary studies in 1978. In 1985, PNL developed a comprehensive QA program for R ampersand D activities in support of two of the proposed repository projects. This QA program was developed by the PNL QA department with a significant amount of support assistance and guidance from PNL upper management, the Basalt Waste Isolation Project (BWIP), and the Salt Repository Program Office (SPRO). The QA program has been revised to add a three-level feature and is currently being implemented on projects sponsored by the Office of Geologic Repositories (DOE/OGR), Repository Technology Program (DOE-CH), Nevada Nuclear Waste Storage Investigation (NNWSI) Project, and other HLW projects

Vietnam Project For Production Of Radioactive Beam Based On ISOL Technique With The Dalat Reactor

International Nuclear Information System (INIS)

Le Hong Khiem; Phan Viet Cuong; Fadi Ibrahim

2011-01-01

The presence in Vietnam of Dalat nuclear reactor dedicated to fundamental studies is a unique opportunity to produce Radioactive Ion (RI) Beams with the fission of a 235 U induced by the thermal neutrons produced by the reactor. We propose to produce RI beams at the Dalat nuclear reactor using ISOL (Isotope Separation On-Line) technique. This project should be a unique opportunity for Vietnamese nuclear physics community to use its own facilities to produce RI beams for studying nuclear physics at an international level. (author)

Can we talk? Communications management for the Waste Isolation Pilot Plant, a complex nuclear waste management project

Energy Technology Data Exchange (ETDEWEB)

Goldstein, S.A.; Pullen, G.M.; Brewer, D.R.

1995-07-01

Sandia Nuclear Waste Management Program is pursuing for DOE an option for permanently disposing radioactive waste in deep geologic repositories. Included in the Program are the Waste Isolation Pilot Plant (WIPP) Project for US defense program mixed waste the Yucca Mountain Project (YMP) for spent power reactor fuel and vitrified high-level waste, projects for other waste types, and development efforts in environmental decision support technologies. WIPP and YMP are in the public arena, of a controversial nature, and provide significant management challenges. Both projects have large project teams, multiple organization participants, large budgets, long durations, are very complex, have a high degree of programmatic risk, and operate in an extremely regulated environment requiring legal defensibility. For environmental projects like these to succeed, SNL`s Program is utilizing nearly all areas in PMI`s Project Management Body of Knowledge (PMBOK) to manage along multiple project dimensions such as the physical sciences (e.g., geophysics and geochemistry; performance assessment; decision analysis) management sciences (controlling the triple constraint of performance, cost and schedule), and social sciences (belief systems; public participation; institutional politics). This discussion focuses primarily on communication challenges active on WIPP. How is the WIPP team meeting the challenges of managing communications?`` and ``How are you approaching similar challenges?`` will be questions for a dialog with the audience.

Isolated systems with wind power. An implementation guideline

DEFF Research Database (Denmark)

Clausen, Niels-Erik; Bindner, Henrik W.; Frandsen, Sten Tronæs

2001-01-01

The overall objective of this research project is to study the development of methods and guidelines rather than "universal solutions" for the use of wind energy in isolated communities. So far most studies of isolated systems with wind power have beencase-oriented and it has proven difficult...... feasibility of isolated power supply systems with wind energy. General guidelines and checklists on which facts and data are needed to carry out a projectfeasibility analysis are presented as well as guidelines how to carry out the project feasibility study and the environmental analysis. The report outlines...... the results of the project as a set of proposed guidelines to be applied when developing a projectcontaining an application of wind in an isolated power system. It is the author's hope that this will facilitate the development of projects and enhance electrification of small rural communities in developing...

Cold-blooded vertebrates at the proposed Reference Repository Location in southeastern Washington

International Nuclear Information System (INIS)

Fitzner, R.E.

1988-01-01

The information in this interim report will be used to design future environmental monitoring plans and assess impacts related to Basalt Waste Isolation Project (BWIP) activities. New reports will be issued as more data become available. Five study locations were established to study cold-blooded vertebrates in the vicinity of the proposed Reference Repository Location. Four study sites were in shrub-dominated stands of vegetation; the other site was devoid of shrubs because of a range fire in 1984. The side-blotched lizard (Uta stansburiana), trapped in four of the five plots, was the only lizard species captured. It was not trapped in the one plot dominated by spiny hopsage (Grayia spinosa) shrubs. It is uncertain whether the side-blotched lizard is absent from this particular vegetation type, or if the population is too low to have been detected in the relatively short time span of the investigation. Two species of snakes were captured, gopher snakes (Pituophis melanoleucus) and green racers (Coluber constrictor mormon). The number of snakes captured was too small to detect any distributional pattern in space or time. Studies are continuing. 4 refs., 9 figs., 3 tabs

Cold-blooded vertebrates at the proposed Reference Repository Location in southeastern Washington

Energy Technology Data Exchange (ETDEWEB)

Fitzner, R.E.

1988-01-01

The information in this interim report will be used to design future environmental monitoring plans and assess impacts related to Basalt Waste Isolation Project (BWIP) activities. New reports will be issued as more data become available. Five study locations were established to study cold-blooded vertebrates in the vicinity of the proposed Reference Repository Location. Four study sites were in shrub-dominated stands of vegetation; the other site was devoid of shrubs because of a range fire in 1984. The side-blotched lizard (Uta stansburiana), trapped in four of the five plots, was the only lizard species captured. It was not trapped in the one plot dominated by spiny hopsage (Grayia spinosa) shrubs. It is uncertain whether the side-blotched lizard is absent from this particular vegetation type, or if the population is too low to have been detected in the relatively short time span of the investigation. Two species of snakes were captured, gopher snakes (Pituophis melanoleucus) and green racers (Coluber constrictor mormon). The number of snakes captured was too small to detect any distributional pattern in space or time. Studies are continuing. 4 refs., 9 figs., 3 tabs.

Interim housing conditions profile, Benton and Franklin Counties, Washington: BWIP Repository Project: Working draft

International Nuclear Information System (INIS)

Bolton, P.A.

1987-11-01

This report describes the housing stock and its availability in Benton and Franklin counties. Depending on the specific measures, data are presented for the entire MSA, for Benton and Franklin counties separately, for incorporated and unincorporated areas within the counties, and for specific incorporated areas. The most detailed data are available for the two counties and for the major cities of Kennewick and Richland in Benton County and Pasco in Franklin County. In 1986, 64 percent of the population of Benton County and 66 percent of the housing units were in Kennewick and Richland. Seventy-three percent of the population and 75 percent of the housing were in the incorporated area of Benton County. In Franklin County, Pasco accounted for 52 percent of the county's 1986 population and 57 percent of its housing. Fifty-nine percent of the population and 63 percent of the housing were in the incorporated areas of Franklin County. More detailed data are needed to fully describe the housing conditions in the jurisdictions described here. 13 refs., 9 tabs

Assessing social and economic effects of perceived risk: Workshop summary: Draft: BWIP Repository Project

International Nuclear Information System (INIS)

Nealey, S.M.; Liebow, E.B.

1988-03-01

The US Department of Energy sponsored a one-day workshop to discuss the complex dimensions of risk judgment formation and the assessment of social and economic effects of risk perceptions related to the permanent underground storage of highly radioactive waste from commercial nuclear power plants. Affected parties have publicly expressed concerns about potentially significant risk-related effects of this approach to waste management. A selective review of relevant literature in psychology, decision analysis, economics, sociology, and anthropology was completed, along with an examination of decision analysis techniques that might assist in developing suitable responses to public risk-related concerns. The workshop was organized as a forum in which a set of distinguished experts could exchange ideas and observations about the problems of characterizing the effects of risk judgments. Out of the exchange emerged the issues or themes of problems with probabilistic risk assessment techniques are evident; differences exist in the way experts and laypersons view risk, and this leads to higher levels of public concern than experts feel are justified; experts, risk managers, and decision-makers sometimes err in assessing risk and in dealing with the public; credibility and trust are important contributing factors in the formation of risk judgments; social and economic consequences of perceived risk should be properly anticipated; improvements can be made in informing the public about risk; the role of the public in risk assessment, risk management and decisions about risk should be reconsidered; and mitigation and compensation are central to resolving conflicts arising from divergent risk judgments. 1 tab

Evaluation and compilation of DOE waste package test data: Biannual report, August 1986-January 1987

International Nuclear Information System (INIS)

Interrante, C.; Escalante, E.; Fraker, A.; Harrison, S.; Shull, R.; Linzer, M.; Ricker, R.; Ruspi, J.

1987-10-01

This report summarizes results of the National Bureau of Standards (NBS) evaluations of Department of Energy (DOE) activities on waste packages designed for containment of radioactive high-level nuclear waste (HLW). The waste package is a proposed engineered barrier that is part of a permanent repository for HLW. Metal alloys are the principal barriers within the engineered system. Technical discussions are given for the corrosion of metals proposed for the canister, particularly carbon and stainless steels, and copper. In the section on tuff, the current level of understanding of several canister materials is questioned. Within the Basalt Waste Isolation Project (BWIP) section, discussions are given on problems concerning groundwater, materials for use in the metallic overpack, and diffusion through the packing. For the proposed salt site, questions are raised on the work on both ASTM A216 Steel and Ti-Code 12. NBS work related to the vitrification of HLW borosilicate glass at the West Valley Demonstration Project (WVDP) and the Defense Waste Processing Facility (DWPF) is covered. NBS reviews of selected DOE technical reports and a summary of current waste-package activities of the Materials Characterization Center (MCC) is presented. Using a database management system, a computerized database for storage and retrieval of reviews and evaluations of HLW data has been developed and is described. 17 refs., 2 figs., 2 tabs

Isolated systems with wind power. An implementation guideline

Energy Technology Data Exchange (ETDEWEB)

Clausen, N.E.; Bindner, H.; Frandsen, S.; Hansen, J.C.; Hansen, L.H.; Lundsager, P.

2001-06-01

The overall objective of this research project is to study the development of methods and guidelines rather than 'universal solutions' for the use of wind energy in isolated communities. So far most studies of isolated systems with wind power have been case-oriented and it has proven difficult to extend results from one project to another, not least due to the strong individuality that has characterised such systems in design and implementation. In the present report a unified and generally applicable approach is attempted in order to support a fair assessment of the technical and economical feasibility of isolated power supply systems with wind energy. General guidelines and checklists on which facts and data are needed to carry out a project feasibility analysis are presented as well as guidelines how to carry out the project feasibility study and the environmental analysis. The report outlines the results of the project as a set of proposed guidelines to be applied when developing a project containing an application of wind in an isolated power system. It is the author's hope that this will facilitate the development of projects and enhance electrification of small rural communities in developing countries. (au)

A review of drilled shaft sealing for the Basalt Waste Isolation Project

International Nuclear Information System (INIS)

1981-01-01

Questions have been raised concerning the ability of the drillers of the exploratory shaft for the Basalt Waste Isolation program to develop an effective seal against water inflow down the annular space between the shaft casing and shaft wall into the mined chambers. We understand the need for shaft integrity and the concern of those responsible for the shaft planning. The purpose of this report is to give documentation to allay the fears of those who may have questions remaining in their minds concerning the prospects for a dry shaft. Included in this report are discussions of five projects where shaft sealing was effective in drilled shafts and one project where the material which is recommended for the exploratory shaft was used effectively in a conventional shaft. Also discussed is the recommended multitier approach toward shaft sealing which will, if adopted, use all of the current state of the art techniques to assure the watertightness of the shaft. It should be pointed out that none of the projects described here used all of the safeguards which are recommended in this program. If any of the materials and procedures recommended here are omitted, then of course the possibility increases for water migration through the casing-borehole annulus. It is our considered opinion that if the program recommended is adopted there will be no water inflow into the shaft, but if we are wrong or if, through human error, the program is not executed correctly, that we have devices and procedures available to us which will facilitate remedial work to perfect seal in the shaft. 4 refs., 3 figs., 1 tab

Summary of computational support and general documentation for computer code (GENTREE) used in Office of Nuclear Waste Isolation Pilot Salt Site Selection Project

International Nuclear Information System (INIS)

Beatty, J.A.; Younker, J.L.; Rousseau, W.F.; Elayat, H.A.

1983-01-01

A Decision Tree Computer Model was adapted for the purposes of a Pilot Salt Site Selection Project conducted by the Office of Nuclear Waste Isolation (ONWI). A deterministic computer model was developed to structure the site selection problem with submodels reflecting the five major outcome categories (Cost, Safety, Delay, Environment, Community Impact) to be evaluated in the decision process. Time-saving modifications were made in the tree code as part of the effort. In addition, format changes allowed retention of information items which are valuable in directing future research and in isolation of key variabilities in the Site Selection Decision Model. The deterministic code was linked to the modified tree code and the entire program was transferred to the ONWI-VAX computer for future use by the ONWI project

Evaluation of the Safety Analysis Report for the Waste Isolation Pilot Plant Project

International Nuclear Information System (INIS)

Little, M.S.

1985-05-01

The Safety Analysis Report (SAR) for the Waste Isolation Pilot Plant (WIPP) Project was first published by the US Department of Energy (DOE), WIPP Project Office (WPO) in 1980. Since that time a total of eight amendments to this Report have been published. As part of its independent evaluation of the WIPP Project for the State of New Mexico, the Environmental Evaluation Group (EEG) maintains a continuing technical assessment of the information in this Report and its amendments. Beginning with the initial publication, and following the amendments, the EEG prepares detailed written comments and recommendations which are submitted to the WPO for consideration in future amendments. The WPO has made many substantial changes to the SAR in response to the EEG's comments. On frequent occasions, meetings between the two groups have been held in an effort to reach an accord on some of the more controversial issues. These meetings generally have been very constructive, but several important areas of conflict remain. In many instances, these areas represent changes which are to be considered by the WPO at some future date, rather than irreconcilable issues. The most important issues remaining to be resolved are included in the discussions of this report, and could be summarized as follows: (1) An amendment of the topical content to be more in accord with the DOE Order 5481.1A and AL 5481.1A. (2) Substantial revisions of the classification of components, structures and systems, and related quality assurance. (3) Revisions to the site geological and hydrologic data based on studies agreed to between DOE and the State

The NERAM project: A model for Electric Power Enterprise in Isolated Communities in the Amazon; O Projeto NERAM - Modelo de Negocio de Energia Eletrica em Comunidades Isoladas na Amazonia

Energy Technology Data Exchange (ETDEWEB)

Rodrigues, Monica; Xavier, Diogo; Souza, Rubem; Seye, Omar; Santos, Eyde dos; Freitas, Katriana; Moraes, Marcia [Universidade Federal do Amazonas (CDEAM/UFAM), Manaus, AM (Brazil). Centro de Desenvolvimento Energetico Amazonico], Email: monica.mzman@gmail.com

2006-07-01

This work presents an overview of the ongoing NERAM - A Model for Electric Power Enterprise in Isolated Communities in the Amazon, a project from CDEAM (Center for Amazonian Energetic Development), financed by CNPq (National Counsel of Technological and Scientific Development). This project aims at establishing a model for rural electrification associated with income generation and based on the sustainable use of local resources. This paper presents the most relevant aspects of the context as well as a general description of the project. The current rural power supply, the socio-economic condition of isolated communities, the income generation from acai pulp and the system generation, the biomass characterization are topics addressed herewith. This text aims at a global outlook and to provide basic understanding of the project, since specific papers will address these issues separately and in depth. (author)

Outcomes of an infection prevention project focusing on hand hygiene and isolation practices.

Science.gov (United States)

Aragon, Daleen; Sole, Mary Lou; Brown, Scott

2005-01-01

Nosocomial infections are a major health problem for hospitalized patients and their families. Since the 1800s, hand hygiene has been recognized as the single best method to prevent the spread of pathogens and nosocomial infections. Despite this fact, many healthcare workers do not adhere to hand hygiene policies. The Centers for Disease Control and Prevention issued a guideline for hand hygiene practices in 2002. Multifaceted approaches to improve hand hygiene have been shown to increase compliance among healthcare workers and subsequently reduce infections. A performance improvement project was initiated to implement this guideline and other strategies to prevent nosocomial infection. This article summarizes the performance improvement processes and the preliminary outcomes on adherence to infection prevention policies related to hand hygiene and isolation practices. Clinically and statistically significant increases were noted for hand hygiene prior to patient care and in wearing masks when indicated. Nurses and patient care technicians had the greatest increases in compliance. Increases in hand hygiene after patient contact and wearing of gown and gloves were also noted, but results were not statistically significant. Nosocomial infection rates from antibiotic-resistant organisms decreased in the first surveillance, but rates increased during the 1-year surveillance. Consumption of alcohol-based foam disinfectant doubled from baseline. Findings are consistent with other published studies. The project will continue with further reinforcement and education over the second year.

Condensed listing of surface boreholes at the Waste Isolation Pilot Plant Project through 31 December 1995

International Nuclear Information System (INIS)

Hill, L.R.; Aguilar, R.; Mercer, J.W.; Newman, G.

1997-01-01

This report contains a condensed listing of Waste Isolation Pilot Plant (WIPP) project surface boreholes drilled for the purpose of site selection and characterization through 31 December 1995. The US Department of Energy (DOE) sponsored the drilling activities, which were conducted primarily by Sandia National Laboratories. The listing provides physical attributes such as location (township, range, section, and state-plane coordinates), elevation, and total borehole depth, as well as the purpose for the borehole, drilling dates, and information about extracted cores. The report also presents the hole status (plugged, testing, monitoring, etc.) and includes salient findings and references. Maps with borehole locations and times-of-drilling charts are included

Economic comparison of crystalline ceramic and glass waste forms for HLW disposal

International Nuclear Information System (INIS)

McKee, R.W.; Daling, P.M.; Wiles, L.E.

1983-05-01

A titanate-based, crystalline ceramic produced by hot isostatic pressing has been proposed as a potentially more stable and improved waste form for high-level nuclear waste disposal compared to the currently favored borosilicate glass waste form. This paper describes the results of a study to evaluate the relative costs for disposal of high-level waste from a 70,000 metric ton equivalent (MTE) system. The entire waste management system, including waste processing and encapsulation, transportation, and final repository disposal, was included in this analysis. The repository concept is based on the current basalt waste isolation project (BWIP) reference design. A range of design basis alternatives is considered to determine if this would influence the relative economics of the two waste forms. A thermal analysis procedure was utilized to define optimum canister sizes to assure that each waste form was compared under favorable conditions. Repository costs are found to favor the borosilicate glass waste form while transportation costs greatly favor the crystalline ceramic waste form. The determining component in the cost comparison is the waste processing cost, which strongly favors the borosilicate glass process because of its relative simplicity. A net cost advantage on the order of 12% to 15% on a waste management system basis is indicated for the glass waste form

Waste-isolation projects, FY 1978

International Nuclear Information System (INIS)

Ramspott, L.D.

1979-01-01

This report describes Lawrence Livermore Laboratory (LLL) activities during FY 1978 in support of the National Waste Terminal Storage Program. Current projects at LLL fall into three categories: (1) field testing, (2) laboratory rock mechanics measurements, and (3) laboratory studies of sorption and leaching. Field test activities conducted in the Climax granite at the Nevada Test Site included electrical heater tests, preparation for a spent-fuel-storage test, and planning for a series of rock mechanics tests. The heater tests determined the in situ thermal properties of Climax granite and its in situ permeability as a function of rock temperature. The two main laboratory rock mechanics projects involved (1) measurement of the permeability, electrical conductivity, and acoustic velocity of 15-cm-diam cores of granitic rocks over a range of confining pressure, pore (water) pressure, and deviatoric stress, and (2) measurement of rock thermal properties as a function of temperature and confining pressure in the presence of pore fluids to 770 0 K and 200 Mpa. The leaching studies made use of an LLL-designed, single-pass leaching apparatus with three solutions, two leach temperatures, and three flow rates. The material evaluated was Np--Pu-doped simulated waste glass from Battelle Pacific Northwest Laboratories. The sorption studies involved standard static measurements of the equilibrium distribution coefficient (K/sub d/) for various radionuclides on a variety of rocks, and flow-through-core studies of dynamic sorption

The current status of seismic isolation technology in the United States

International Nuclear Information System (INIS)

Kelly, J.M.

1992-01-01

Seismic isolation is at the present time in a very active state of development. Many new types of isolation systems are being explored and elastomeric isolators, the system which has been employed on almost all isolation systems completed to date, continue to undergo improvements. At least one dozen large projects, either new or the retrofit of existing buildings, have been completed and design studies are underway for at least another one dozen large projects. A large experimental research project for isolators with nuclear reactor application has been carried out over the past few years at EERC. This program has involved shake table testing and the testing of full-scale and model isolators. A wide variety of isolators have been tested including low-shape factor, moderate-shape factor, and very high-shape factor elastomer bearings. The range of elastomers that have been tested include low-damping, high-damping, and very low-modulus compounds. Full-size and model isolators have been tested to failure in several failure modes and the safety margins for isolation systems have been established. The test results have shown that properly designed and manufactured isolators for nuclear reactor applications can sustain levels of loading beyond any possible seismic input and demonstrate that failure of an isolation system cannot occur before failure of the isolated structure. Thus, the use of isolation can only have beneficial contributions to the protection of nuclear facilities, internal piping, and equipment. The presentation will review the latest developments in the implementation of base isolation and describe the results of the test program for its application to nuclear facilities. (author)

Emotion regulation during isolation

Czech Academy of Sciences Publication Activity Database

Poláčková Šolcová, Iva; Šolcová, Iva

2012-01-01

Roč. 47, Suppl. 1 (2012) ISSN 0020-7594. [International Congress of Psychology /30./. 22.07.2012-27.07.2012, Cape Town] R&D Projects: GA ČR(CZ) GAP407/11/2226 Institutional support: RVO:68081740 Keywords : emotion regulation * isolation * Mars500 Subject RIV: AN - Psychology

WIPP: Waste Isolation Pilot Plant

International Nuclear Information System (INIS)

1984-01-01

The following aspects of the Waste Isolation Pilot Plant are discussed briefly: history and site selection; salt as a disposal medium; transporting waste materials; early key events; impacts on New Mexico; project organization; and site certification profile

The accelerated ISOL technique and the SPIRAL project

International Nuclear Information System (INIS)

Villari, A.C.C.

2001-01-01

The accelerated ISOL technique is presented as an introduction to the present status of the SPIRAL facility. SPIRAL is based on the very high intensity light and heavy ion beams available at GANIL. The facility will deliver radioactive beams with energies in the range between 1.7 A and 25 A MeV. The presently target-ion source production system, as well the new developments undertaken by the target ion-source group at GANIL are presented. (authors)

Basalt Waste Isolation Project. Annual report, fiscal year 1979

International Nuclear Information System (INIS)

1979-11-01

This project is aimed at examining the feasibility and providing the technology to design and construct a radwaste repository in basalt formations beneath and within the Hanford Site. The project is divided into seven areas: systems integration, geosciences, hydrologic studies, engineered barriers, near-surface test facility, engineering testing, and repository engineering. This annual report summarizes key investigations in these seven areas

Development of analysis methods for seismically isolated nuclear structures

International Nuclear Information System (INIS)

Yoo, Bong; Lee, Jae-Han; Koo, Gyeng-Hoi

2002-01-01

KAERI's contributions to the project entitled Development of Analysis Methods for Seismically Isolated Nuclear Structures under IAEA CRP of the intercomparison of analysis methods for predicting the behaviour of seismically isolated nuclear structures during 1996-1999 in effort to develop the numerical analysis methods and to compare the analysis results with the benchmark test results of seismic isolation bearings and isolated nuclear structures provided by participating countries are briefly described. Certain progress in the analysis procedures for isolation bearings and isolated nuclear structures has been made throughout the IAEA CRPs and the analysis methods developed can be improved for future nuclear facility applications. (author)

Beam Optics for Typical Part of ISOL Beam Lines

International Nuclear Information System (INIS)

Jang, Ji Ho; Kwon, Hyeok Jung; Kim, Han Sung; Cho, Yong Sub

2013-01-01

KOMAC (Korea Multi-purpose Accelerator Complex) is doing a project, the detailed design of the ISOL beam lines for the heavy ion accelerator project of IBS (Institute of Basic Science) from August 2013 to February 2014. The heavy ion beams are transported by using the electrostatic quadrupoles and electrostatic benders between the equipment. The work-scope of the project is the beam optics design of the beam lines and the detailed design of the beam optics components, the electrostatic quadrupoles and the electrostatic bender. This work summarized the initial result of beam optics design of the beam line. We performed the beam optics simulation in two regions of ISOL beam lines and found that beam envelope is less than 2 cm. We will check that the poletip file values are reasonable or not in near future, and we also applied this method to the other parts of the ISOL beam line and optimize them. The result will be used the detailed design of the electrostatic quadrupoles and benders

Social Disconnectedness, Perceived Isolation, and Health among Older Adults*

OpenAIRE

CORNWELL, ERIN YORK; WAITE, LINDA J.

2009-01-01

Previous research has identified a wide range of indicators of social isolation that pose health risks, including living alone, having a small social network, infrequent participation in social activities, and feelings of loneliness. However, multiple forms of isolation are rarely studied together, making it difficult to determine which aspects of isolation are most deleterious for health. Using population-based data from the National Social Life, Health, and Aging Project, we combine multipl...

A Model of Project and Organisational Dynamics

OpenAIRE

Jenny Leonard

2012-01-01

The strategic, transformational nature of many information systems projects is now widely understood. Large-scale implementations of systems are known to require significant management of organisational change in order to be successful. Moreover, projects are rarely executed in isolation – most organisations have a large programme of projects being implemented at any one time. However, project and value management methodologies provide ad hoc definitions of the relationship between a project ...

Verification of analysis methods for predicting the behaviour of seismically isolated nuclear structures. Final report of a co-ordinated research project 1996-1999

International Nuclear Information System (INIS)

2002-06-01

This report is a summary of the work performed under a co-ordinated research project (CRP) entitled Verification of Analysis Methods for Predicting the Behaviour of Seismically isolated Nuclear Structures. The project was organized by the IAEA on the recommendation of the IAEA's Technical Working Group on Fast Reactors (TWGFR) and carried out from 1996 to 1999. One of the primary requirements for nuclear power plants and facilities is to ensure safety and the absence of damage under strong external dynamic loading from, for example, earthquakes. The designs of liquid metal cooled fast reactors (LMFRs) include systems which operate at low pressure and include components which are thin-walled and flexible. These systems and components could be considerably affected by earthquakes in seismic zones. Therefore, the IAEA through its advanced reactor technology development programme supports the activities of Member States to apply seismic isolation technology to LMFRs. The application of this technology to LMFRs and other nuclear plants and related facilities would offer the advantage that standard designs may be safely used in areas with a seismic risk. The technology may also provide a means of seismically upgrading nuclear facilities. Design analyses applied to such critical structures need to be firmly established, and the CRP provided a valuable tool in assessing their reliability. Ten organizations from India, Italy, Japan, the Republic of Korea, the Russian Federation, the United Kingdom, the United States of America and the European Commission co-operated in this CRP. This report documents the CRP activities, provides the main results and recommendations and includes the work carried out by the research groups at the participating institutes within the CRP on verification of their analysis methods for predicting the behaviour of seismically isolated nuclear structures

The Innavik hydroelectric project

Energy Technology Data Exchange (ETDEWEB)

St-Pierre, S.; McNeil, E.; Gacek, J. [RSW Inc., Montreal, PQ (Canada); Atagotaaluk, E. [Pituvik Landholding Corp., Nunavik, PQ (Canada); Henderson, C. [Lumos Energy, Ottawa, ON (Canada)

2009-07-01

The village of Inukjuak in northern Quebec is not connected to the main electrical grid. This remote village is one of 14 Inuit communities in the Nunavik administrative region where electricity is generated by diesel thermal power plants under the direction of Hydro-Quebec Distribution's Isolated Grid subdivision. The heating of water and buildings is supplied by heavy fuel-oil. A compensation program for the price of fuel-oil is applied in the community. This presentation discussed the need for developing renewable energy sources in order to respond to the energy demands of isolated grids. The community of Inukjuak plans on developing the water resources of the Inukjuak River in order to produce hydroelectricity and reduce the use of diesel fuel. Several possible development sites were identified. The project will contribute to a reduction in energy costs while reducing greenhouse gas emissions. Revenues generated from the power plant will help the village in their economic development by enabling the completion of various community projects. The sustainable development approach taken for the project was discussed and the project's main technical, environmental and social issues were identified. The project is expected to reduce the production of an estimated 8 tons of carbon dioxide emissions by 2011 and nearly 15 tons after 10 years of operation.

Function analysis of steam isolation valves

International Nuclear Information System (INIS)

Persson, R.; Sjoeberg, A.; Aakesson, H.; Kilpi, K.; Noro, H.; Siikonen, T.; Wallen, G.

1981-01-01

Function analysis of system-medium-operated steam isolation valves has been the objective of the Swedish-Finnish IVLS project, the results of which are presented in this report. Theoretical models were to be verified against available experimental data, to some extent from the HDR blowdown experiments, which are part of a German reactor safety program. Finnish hydraulic measurements on a valve model (scale 1:2.15) have been performed to give complementary data. The analysis work has covered the thermal-hydraulic behaviour of steam isolation valves as well as phenomena related to structural mechanics. (Auth.)

Automated data acquisition and analysis system used in the Basalt Waste Isolation Project's Near-Surface Test Facility

International Nuclear Information System (INIS)

Starr, J.L.

1982-12-01

A large minicomputer-based data acquisition and analysis system has been developed by the Basalt Waste Isolation project and is being applied to support research efforts on the response of rock (basalt) to thermal loads from simulated nuclear wastes. This system is believed to be the largest and most powerful system of its type in existence. It scans over 1000 different instruments, for three separate experiments, at a maximum frequency of once every 5 minutes. In addition to data acquisition, the system also performs the functions of data reduction, analog-to-digital conversion, computation of engineering units, data archiving, statistical analysis, and interactive graphics and reports. The system should be of general interest to those concerned with automated monitoring of instrumentation and computer graphics, as applied to large-scale engineering and scientific experimentation, especially in the fields of rock mechanics and nuclear waste disposal

Properties of Oryctes Baculovirus Isolated in Indonesia

Directory of Open Access Journals (Sweden)

Jun Kobayashi

1995-12-01

Full Text Available An Indonesian isolate of Oryctes baculovirus was purified from infected midguts of the rhinoceros beetle (Oryctes rhinoceros by centrifugation on a 10–40% (w/v sucroese gradient. Morphological features of  nucleocapsid including a tail-like projection were very same as those previously reported. Both protein components of purified particles and restriction fragment electrophoresis profiles of viral DNA were similar to those of their isolates of Oryctes baculovirus, although there were some differences. Key words: Baculovirus oryctes, electrophoresis

Project-Based Learning in Scottish Prisons

Science.gov (United States)

Sams, Kirsten

2014-01-01

The article describes the development of a project-based approach to learning in seven Scottish prisons. It argues that the project-based approach is ideally suited to prison education due to its flexibility and ability to enrich the relatively narrow prison curriculum and create meaningful links with wider society, reducing the isolation of…

Keys to success for wind power in isolated power systems

Energy Technology Data Exchange (ETDEWEB)

Hansen, J C; Lundsager, P; Bindner, H; Hansen, L; Frandsen, S [Risoe National Lab., Wind Energy and Atmospheric Physics Dept., Roskilde (Denmark)

1999-03-01

It is generally expected that wind power could contribute significantly to the electricity supply in power systems of small and medium sized isolated communities. The market for such applications of wind power has not yet materialized. Wind power in isolated power systems have the main market potentials in developing countries. The money available world-wide for this technological development is limited and the necessary R and D and pilot programmes have difficult conditions. Consequently, technology developed exclusively for developing countries rarely becomes attractive for consumers, investors and funding agencies. A Danish research project is aimed at studying development of methods and guidelines rather than `universal solutions` for the use of wind energy in isolated communities. This paper report on the findings of the project regarding barriers removal and engineering methods development, with a focus on analysis and specification of user demand and priorities, numerical modeling requirements as well as wind power impact on power quality and power system operation. Input will be provided on these subjects for establishing of common guidelines on relevant technical issues, and thereby enabling the making of trustworthy project preparation studies. (au) EFP-97. 12 refs.

Verification and benchmarking of PORFLO: an equivalent porous continuum code for repository scale analysis

International Nuclear Information System (INIS)

Eyler, L.L.; Budden, M.J.

1984-11-01

The objective of this work was to perform an assessment of prediction capabilities and features of the PORFLO code in relation to its intended use in the Basalt Waste Isolation Project. This objective was to be accomplished through a code verification and benchmarking task. Results were to be documented which either support correctness of prediction capabilities or identify areas of intended application in which the code exhibits weaknesses. A test problem set consisting of 10 problems was developed. Results of PORFLO simulations of these problems were provided for use in this work. The 10 problems were designed to test the three basic computational capabilities or categories of the code. Broken down by physical process, these are heat transfer, fluid flow, and radionuclide transport. Two verification problems were included within each of these categories. They were problems designed to test basic features of PORFLO for which analytical solutions are available for use as a known comparison basis. Hence they are referred to as verification problems. Of the remaining four problems, one repository scale problem representative of intended PORFLO use within BWIP was included in each of the three basic capabilities categories. The remaining problem was a case specifically designed to test features of decay and retardation in radionuclide transport. These four problems are referred to as benchmarking problems, because results computed with an additional computer code were used as a basis for comparison. 38 figures

The ISOL exotic beam facility at LNS: the EXCYT project

International Nuclear Information System (INIS)

Ciavola, G.; Calabretta, L.; Cuttone, G.; Di Bartolo, G.; Finocchiaro, P.; Gammino, S.; Gu, M.; Migneco, E.; Raia, G.; Rifuggiato, D.; Rovelli, A.; Vinciguerra, D.; Qin, J.; Wollnik, H.

1997-01-01

The aim of the EXCYT project (exotics with cyclotron and tandem) is the development of a facility for producing and accelerating exotic beams from 0.2 up to 8 MeV/amu. EXCYT is based on the ''two accelerators'' method. A K=800 superconducting cyclotron, axially injected by the ECR ion source SERSE, will deliver the primary beam. Such a beam will produce the required nuclear species in a modified ISOLDE type target-source complex. When required, a 15 MV tandem Van der Graaff will accelerate the secondary beams. Both accelerators are existing and operational at Laboratorio Nazionale del Sud. Concerning the status of the project, progress has been made in most of the key issues of the project, like the construction of SERSE, cyclotron upgrading, modification of the existing building, high resolution mass separator, and diagnostic equipment for low energy, low intensity beams. (orig.)

The ISOL exotic beam facility at LNS: the EXCYT project

Energy Technology Data Exchange (ETDEWEB)

Ciavola, G.; Calabretta, L.; Cuttone, G.; Di Bartolo, G.; Finocchiaro, P.; Gammino, S.; Gu, M.; Migneco, E.; Raia, G.; Rifuggiato, D.; Rovelli, A.; Vinciguerra, D. [Istituto Nazionale di Fisica Nucleare, Catania (Italy); Qin, J. [Institute of Atomic Energy, Beijing (China); Wollnik, H. [Giessen Univ. (Germany)

1997-04-01

The aim of the EXCYT project (exotics with cyclotron and tandem) is the development of a facility for producing and accelerating exotic beams from 0.2 up to 8 MeV/amu. EXCYT is based on the ``two accelerators`` method. A K=800 superconducting cyclotron, axially injected by the ECR ion source SERSE, will deliver the primary beam. Such a beam will produce the required nuclear species in a modified ISOLDE type target-source complex. When required, a 15 MV tandem Van der Graaff will accelerate the secondary beams. Both accelerators are existing and operational at Laboratorio Nazionale del Sud. Concerning the status of the project, progress has been made in most of the key issues of the project, like the construction of SERSE, cyclotron upgrading, modification of the existing building, high resolution mass separator, and diagnostic equipment for low energy, low intensity beams. (orig.). 8 refs.

Environmental issue identification for the Basalt Waste Isolation Project

International Nuclear Information System (INIS)

Carrell, D.J.; Jones, K.A.

1980-04-01

A preliminary evaluation of environmental issues is provided in this report. It contains summary of the thought process that was used during the area characterization studies for a geological repository for high-level radioactive wastes. Environmental issues are discussed separately for construction, operation, and long term isolation aspects of a repository in basalt. During construction the primary environmental concerns are public perception and water resources; intermediate concerns are air quality, ecosystems, physical resources, and cultural and social resources. During operation, the primary environmental issues concern the transport of radioactive materials and physical resources. Long term environmental issues envolve water resources and borehole plugging

Electric power generation using biomass gasification systems in nature in isolated communities of the Amazon region: project GASEIBRAS; Geracao de eletricidade utilizando sistemas de gaseificacao de biomassa in natura em comunidades isoladas da regiao amazonica: projeto GASEIBRAS

Energy Technology Data Exchange (ETDEWEB)

Coelho, Suani Teixeira; Velazquez, Silvia M. Stortini Goncalves; Santos, Sandra M. Apolinario dos; Lora, Beatriz Acquaro [Universidade de Sao Paulo (CENBIO/USP), SP (Brazil). Centro de Referencia Nacional em Biomassa], e-mails: suani@iee.usp.br, sgvelaz@iee.usp.br, sandra@iee.usp.br, blora@iee.usp.br

2006-07-01

This paper will present the pioneering project of electric energy generation from renewable sources 'GASEIBRAS - Nationalization of the Biomass Gasification Technology and Formation of Human Resources in the Amazon Region', recently approved by the National Advice of Scientific and Technological Development (CNPq) and for the Ministry of Mines and Energy (MME). The GASEIBRAS project intends to use the experience previously acquired in the project GASEIFAMAZ - Comparison between Existing Technologies of Biomass Gasification in Brazil and Exterior and Formation of Human Resources in the North Region, sponsored by FINEP/CTENERG, to develop and construct a 20 kWe biomass gasification system, with total national technology, easy to operate and to maintain, and fed with local available biomass residues. Apart from contributing for the development of the national technology, this project will provide the sustainable development of the isolated communities in the Amazon region. The ongoing development of this project will enable to consolidate the national biomass gasification technology for electricity generation. The implemented prototype will allow the response of this project in other regions of the country, due its tailor made characteristic to attend to small isolated communities, thus supplying decentralized energy from renewable sources, to Amazon region. (author)

Function analysis of steam isolation valves

International Nuclear Information System (INIS)

Persson, R.; Kilpi, K.; Noro, H.; Siikonen, T.; Sjoeberg, A.; Wallen, G.; Aakesson, H.

1981-01-01

Function analysis of system-medium-operated steam isolation valves has been the objective of the Swedish-Finnish IVLS project, the results of which are presented in this report. Theoretical models were to be verified against available experimental data, to some extent from the HDR blowdown experiments, which are part of a German reactor safety program. Finnish hydraulic measurements on a valve model (scale 1:2.15) have been performed to give complementary data. The analysis work has covered the thermal-hydraulic behaviour of steam isolation valves as well as phenomena related to structural mechanics. Work performed under contract with the Swedish Nuclear Power Inspectorate. (Author)

Reliability analysis of containment isolation systems

International Nuclear Information System (INIS)

Pelto, P.J.; Counts, C.A.

1984-06-01

The Pacific Northwest Laboratory (PNL) is reviewing available information on containment systems design, operating experience, and related research as part of a project being conducted by the Division of Systems Integration, US Nuclear Regulatory Commission. The basic objective of this work is to collect and consolidate data relevant to assessing the functional performance of containment isolation systems and to use this data to the extent possible to characterize containment isolation system reliability for selected reference designs. This paper summarizes the results from initial efforts which focused on collection of data from available documents and briefly describes detailed review and analysis efforts which commenced recently. 5 references

Teacher/Intern Partnerships in Isolated Areas: A Project Overview.

Science.gov (United States)

Yarrow, Allan; Ballantyne, Roy; Hansford, Brian; Herschell, Paul; Millwater, Jan

1998-01-01

Describes a collaborative project designed to better prepare Australian preservice teachers for teaching in remote schools through six-week rural mentorship programs and joint preservice and inservice professional development. Discusses how development of partnerships among cooperating institutions and between teachers, student teachers, and the…

Arizona TeleMedicine Project.

Science.gov (United States)

Arizona Univ., Tucson. Coll. of Medicine.

Designed to provide health services for American Indians living on rurally isolated reservations, the Arizona TeleMedicine Project proposes to link Phoenix and Tucson medical centers, via a statewide telecommunications system, with the Hopi, San Carlos Apache, Papago, Navajo, and White Mountain Apache reservations. Advisory boards are being…

THE AGORA HIGH-RESOLUTION GALAXY SIMULATIONS COMPARISON PROJECT. II. ISOLATED DISK TEST

Energy Technology Data Exchange (ETDEWEB)

Kim, Ji-hoon [Kavli Institute for Particle Astrophysics and Cosmology, SLAC National Accelerator Laboratory, Menlo Park, CA 94025 (United States); Agertz, Oscar [Department of Physics, University of Surrey, Guildford, Surrey, GU2 7XH (United Kingdom); Teyssier, Romain; Feldmann, Robert [Centre for Theoretical Astrophysics and Cosmology, Institute for Computational Science, University of Zurich, Zurich, 8057 (Switzerland); Butler, Michael J. [Max-Planck-Institut für Astronomie, D-69117 Heidelberg (Germany); Ceverino, Daniel [Zentrum für Astronomie der Universität Heidelberg, Institut für Theoretische Astrophysik, D-69120 Heidelberg (Germany); Choi, Jun-Hwan [Department of Astronomy, University of Texas, Austin, TX 78712 (United States); Keller, Ben W. [Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1 (Canada); Lupi, Alessandro [Institut d’Astrophysique de Paris, Sorbonne Universites, UPMC Univ Paris 6 et CNRS, F-75014 Paris (France); Quinn, Thomas; Wallace, Spencer [Department of Astronomy, University of Washington, Seattle, WA 98195 (United States); Revaz, Yves [Institute of Physics, Laboratoire d’Astrophysique, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne (Switzerland); Gnedin, Nickolay Y. [Particle Astrophysics Center, Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Leitner, Samuel N. [Department of Astronomy, University of Maryland, College Park, MD 20742 (United States); Shen, Sijing [Kavli Institute for Cosmology, University of Cambridge, Cambridge, CB3 0HA (United Kingdom); Smith, Britton D., E-mail: me@jihoonkim.org [Institute for Astronomy, University of Edinburgh, Royal Observatory, Edinburgh EH9 3HJ (United Kingdom); Collaboration: AGORA Collaboration; and others

2016-12-20

Using an isolated Milky Way-mass galaxy simulation, we compare results from nine state-of-the-art gravito-hydrodynamics codes widely used in the numerical community. We utilize the infrastructure we have built for the AGORA High-resolution Galaxy Simulations Comparison Project. This includes the common disk initial conditions, common physics models (e.g., radiative cooling and UV background by the standardized package Grackle) and common analysis toolkit yt, all of which are publicly available. Subgrid physics models such as Jeans pressure floor, star formation, supernova feedback energy, and metal production are carefully constrained across code platforms. With numerical accuracy that resolves the disk scale height, we find that the codes overall agree well with one another in many dimensions including: gas and stellar surface densities, rotation curves, velocity dispersions, density and temperature distribution functions, disk vertical heights, stellar clumps, star formation rates, and Kennicutt–Schmidt relations. Quantities such as velocity dispersions are very robust (agreement within a few tens of percent at all radii) while measures like newly formed stellar clump mass functions show more significant variation (difference by up to a factor of ∼3). Systematic differences exist, for example, between mesh-based and particle-based codes in the low-density region, and between more diffusive and less diffusive schemes in the high-density tail of the density distribution. Yet intrinsic code differences are generally small compared to the variations in numerical implementations of the common subgrid physics such as supernova feedback. Our experiment reassures that, if adequately designed in accordance with our proposed common parameters, results of a modern high-resolution galaxy formation simulation are more sensitive to input physics than to intrinsic differences in numerical schemes.

Myoglobin Structure and Function: A Multiweek Biochemistry Laboratory Project

Science.gov (United States)

Silverstein, Todd P.; Kirk, Sarah R.; Meyer, Scott C.; Holman, Karen L. McFarlane

2015-01-01

We have developed a multiweek laboratory project in which students isolate myoglobin and characterize its structure, function, and redox state. The important laboratory techniques covered in this project include size-exclusion chromatography, electrophoresis, spectrophotometric titration, and FTIR spectroscopy. Regarding protein structure,…

Micro-gravity Isolation using only Electro-magnetic Actuators

DEFF Research Database (Denmark)

Vinther, D.; Alminde, Lars; Bisgaard, Morten

in the Sixth Student Parabolic Flight Campaign issued by the European Space Agency (ESA). The system consists of six custom made electro magnetic actuators which acts on the isolated platform based on the designed controller and their input from six accelerometers and six infrared position sensors. From......In this paper the design, construction and test of a free floating micro-gravity isolation platform to reduce the acceleration dose on zero gravity experiments on e.g. the International Space Station (ISS) is discussed. During the project a system is specified and constructed whereupon it is tested...

Micro-gravity Isolation using only Electro-magnetic Actuators

DEFF Research Database (Denmark)

Vinther, D.; Alminde, Lars; Bisgaard, Morten

2004-01-01

in the Sixth Student Parabolic Flight Campaign issued by the European Space Agency (ESA). The system consists of six custom made electro magnetic actuators which acts on the isolated platform based on the designed controller and their input from six accelerometers and six infrared position sensors. >From......In this paper the design, construction and test of a free floating micro-gravity isolation platform to reduce the acceleration dose on zero gravity experiments on e.g. the International Space Station (ISS) is discussed. During the project a system is specified and constructed whereupon it is tested...

Isolated Early-type Galaxies in the 2dFGRS

Science.gov (United States)

Fuse, Christopher R.; Lamir, C.

2014-01-01

Isolated galaxies are systems that have experienced limited external perturbations, thus the properties of these galaxies are largely due to internal processes. The features of isolated early-type galaxies (IEGs) provide a baseline from which to compare early-type systems residing in higher-density environments. We use the Two-Degree Field Galaxy Redshift Survey (2dFGRS) and the NASA Extragalactic Database (NED) to identify IEGs in the nearby universe. Search criteria in the 2dFGRS were chosen to insure that the IEGs have remained separated from neighboring galaxies for the majority of their lifetimes. Isolated galaxies are chosen utilizing a minimum projected physical separation of 1 Mpc from any neighboring non-dwarf galaxy brighter than Mb = -16.5 mags. A minimum redshift separation of 350 km/s between a candidate galaxy and a neighboring was imposed to further insure the candidate’s isolation. Early results of the search for isolated early-type galaxies in the southern sky are presented.

Advanced Ground Systems Maintenance Enterprise Architecture Project

Science.gov (United States)

Perotti, Jose M. (Compiler)

2015-01-01

The project implements an architecture for delivery of integrated health management capabilities for the 21st Century launch complex. The delivered capabilities include anomaly detection, fault isolation, prognostics and physics based diagnostics.

3D seismic isolation for advanced N.P.P application. Hydraulic 3-Dimensional base-isolation system

International Nuclear Information System (INIS)

Shimada, Takahiro; Kashiwazaki, Akihiro; Fujiwaka, Tatsuya; Moro, Satoshi

2003-01-01

In Japan, a number of three-dimensional base isolation systems have been studied for application to new nuclear plant concepts such as the FBR, but these effects have not so far yielded practically applicable results. The impeding factor has been the difficulty of obtaining an adequate capacity on the vertical isolator for supporting the mass of an actual structure and for suppressing rocking motion. In this paper, we propose a new three-dimensional base isolation system that should solve the foregoing problem. The system is constituted of a set of hydraulic load-carrying cylinders connected to accumulator units containing a compressed gas, another set of rocking-suppression cylinders connected in series, and a laminated rubber bearing laid under each load-carrying cylinder. The present paper covers a basic examination for applying the proposed system to a commercialized FBR now under development in Japan, together with static and dynamic loading tests performed on a scale model to verify expected system performance. Response and analysis reflecting the test results has indicated the proposed system to be well applicable to the envisaged commercialized FBR. The study was undertaken as part of an R and D project sponsored by the government for realizing a three-dimensional seismic isolation system applicable to future FRB's. (author)

Hormonal changes during a long term isolation (SFINCSS-99 project)

Science.gov (United States)

Larina, I.; Custaud, M.; Gauquelin-Koch, G.; Gharib, C.; Grigoriev, A.; Nichiporuk, I.

Long duration of space mission and functioning in Earth's orbit of the International Space Station make humans put up with spatial constraint for many months. From previous studies, it appears that confinement and inactivity can induce great psychological and physiological modifications by social and sensory deprivation. SFINCSS-99 experiment had the goal to determine the cardiovascular and the hormonal pattern of blood volume regulating hormones responses. Simulation experiments were performed in pressurized chambers outfitted with technical infrastructure including the systems for air regeneration, thermal and humidity air control, power supply, communications, TV monitoring, gas analysis and local electronic network. Three groups of test-subjects were functioning in parallel in adjacent modules, which mocked the ISS Russian and others segments. One33 crew (group I) occupied the 100 m module and the others the 200 m module (II &III). They could communicate and work together. Group I consisted from Russian males- volunteers aged of 37 to 48 who spent 240 days in chamber. Group II included 4 males (one German and three Russians) aged from 27 to 45, spent 110 days in isolation. In blood samples, drawing before, during and after isolation's period hormones were determined, in urine samples - excretion of hormones, electrolytes, nitrites, nitrates, and osmolality. The increase of plasma volume (hematocrit decrease in Group I was 13,2%: 42,7+/-0,5 vs 39,2+/-1,2; pGroup II - 4,1%: 44,3+/-1,0 vs 43,3+/-2,6) in association with a tendency to decrease in plasma renin activity (in Group I 13,1+/-3,5 vs 27,8+/-6,0) was likely to be due to decreased sympathetic activity, this do agree with the changes in urinary catecholamine (CA) during confinement. Urinary CA were significantly higher during the recovery period than during confinement (in Group I 341+/-44 vs 240+/-19, p< 0,05). This suggests that the sympathoadrenal system was activated, and agrees with the increase of

Testimony of Dr. Raul A. Deju, Basalt Waste Isolation Project, before the Subcommittee on Energy Research and Production, Committee on Sceince and Technology, United States House of Representatives, March 2, 1983

Energy Technology Data Exchange (ETDEWEB)

1983-01-01

Status of the Basalt Waste Isolation Project is given. Three key concerns have been identified that need to be resolved to either confirm or eliminate the basalts as a potential nuclear waste repository host medium. They are: A thorough understanding of the groundwater hydrology beneath the Hanford Site is needed to assure that a repository in basalt will not contribute unacceptable amounts of contaminants to the accessible environment. Our ability to construct a repository shaft and a network of underground tunnels needs to be fully demonstrated through an exploratory shaft program. Our ability to ultimately seal a repository, such that its integrity and the isolation of the waste are guaranteed, needs to be demonstrated.

Antimicrobial activity of Streptomyces spp. Isolates from vegetable plantation soil

Directory of Open Access Journals (Sweden)

Isnaeni

2016-05-01

Full Text Available Fifteen Streptomyces isolates were isolated from soil in some different location on vegetable plantation at agriculture standard condition. The isolates were assessed for their antibacterial activity against Mycobacterium tuberculosis (MTB ATCC H37RV and mycobacterial which isolated from Dr. Soetomo Hospital patients in Surabaya. The International Streptomyces Project 4 (ISP4 and Middlebrook 7H9 (MB7H9 wwere used as growth or fermentation medium. The screening of inhibition activity was performed using turbidimetry and spot-test on agar medium. Results shown that 33.3% of the isolates (5 isolates have anti-mycobacterial activities. The first line anti tuberculosis drug rifampicin, (RIF, ethambutol (EMB, isoniazid (INH, and pyrazinamide (PZA were used as standards or positive controls with concentration 20 ppm. Optical density of crude fermentation broth concentrated from five isolates relatively lower than five anti-tuberculosis drug activity standard, although their activities against some microbial were similar to the standard at spot-test. The most efficient isolate shown anti-mycobacterial activity was Streptomyces B10 which identified as Streptomyces violaceousniger. In addition, fatty acid methyl ester (FAME profile of gas chromatography-mass spectrometry chromatogram of each isolates were studied and compared to Streptomyces spp. Keywords: Anti-mycobacterial, Mycobacterium tuberculosis, Streptomyces spp.

FY-1981 project status for the Transuranic Waste Treatment Facility

International Nuclear Information System (INIS)

Benedetti, R.L.; Tait, T.D.

1981-11-01

The primary objective of the Transuranic Waste Treatment Facility (TWTF) Project is to provide a facility to process low-level transuranic waste stored at the Idaho National Engineering Laboratory (INEL) into a form acceptable for disposal at the Waste Isolation Pilot Plant. This report provides brief summary descriptions of the project objectives and background, project status through FY-1981, planned activities for FY-1982, and the EG and G TWTF Project office position on processing INEL transuranic waste

Project Management Plan for the Idaho National Engineering Laboratory Waste Isolation Pilot Plant Experimental Test Program

International Nuclear Information System (INIS)

Connolly, M.J.; Sayer, D.L.

1993-11-01

EG ampersand G Idaho, Inc. and Argonne National Laboratory-West (ANL-W) are participating in the Idaho National Engineering Laboratory's (INEL's) Waste Isolation Pilot Plant (WIPP) Experimental Test Program (WETP). The purpose of the INEL WET is to provide chemical, physical, and radiochemical data on transuranic (TRU) waste to be stored at WIPP. The waste characterization data collected will be used to support the WIPP Performance Assessment (PA), development of the disposal No-Migration Variance Petition (NMVP), and to support the WIPP disposal decision. The PA is an analysis required by the Code of Federal Regulations (CFR), Title 40, Part 191 (40 CFR 191), which identifies the processes and events that may affect the disposal system (WIPP) and examines the effects of those processes and events on the performance of WIPP. A NMVP is required for the WIPP by 40 CFR 268 in order to dispose of land disposal restriction (LDR) mixed TRU waste in WIPP. It is anticipated that the detailed Resource Conservation and Recovery Act (RCRA) waste characterization data of all INEL retrievably-stored TRU waste to be stored in WIPP will be required for the NMVP. Waste characterization requirements for PA and RCRA may not necessarily be identical. Waste characterization requirements for the PA will be defined by Sandia National Laboratories. The requirements for RCRA are defined in 40 CFR 268, WIPP RCRA Part B Application Waste Analysis Plan (WAP), and WIPP Waste Characterization Program Plan (WWCP). This Project Management Plan (PMP) addresses only the characterization of the contact handled (CH) TRU waste at the INEL. This document will address all work in which EG ampersand G Idaho is responsible concerning the INEL WETP. Even though EG ampersand G Idaho has no responsibility for the work that ANL-W is performing, EG ampersand G Idaho will keep a current status and provide a project coordination effort with ANL-W to ensure that the INEL, as a whole, is effectively and

The Waste Isolation Pilot Plant Performance Assessment Program

International Nuclear Information System (INIS)

Myers, J.; Coons, W.E.; Eastmond, R.; Morse, J.; Chakrabarti, S.; Zurkoff, J.; Colton, I.D.; Banz, I.

1986-01-01

The Waste Isolation Pilot Plant (WIPP) Performance Assessment Program involves a comprehensive analysis of the WIPP project with respect to the recently finalized Environmental Protection Agency regulations regarding the long-term geologic isolation of radioactive wastes. The performance assessment brings together the results of site characterization, underground experimental, and environmental studies into a rigorous determination of the performance of WIPP as a disposal system for transuranic radioactive waste. The Program consists of scenario development, geochemical, hydrologic, and thermomechanical support analyses and will address the specific containment and individual protection requirements specified in 40 CFR 191 sub-part B. Calculated releases from these interrelated analyses will be reported as an overall probability distribution of cumulative release resulting from all processes and events occurring over the 10,000 year post-closure period. In addition, results will include any doses to the public resulting from natural processes occurring over the 1,000 year post-closure period. The overall plan for the WIPP Performance Assessment Program is presented along with approaches to issues specific to the WIPP project

The Isolated Indigenous People of the Brazil-Peru Border: New Threats and Challenges

Directory of Open Access Journals (Sweden)

Hilton S. Nascimento

2011-01-01

Full Text Available The Brazil-Peru border is inhabited by the second largest concentration of peoples in voluntary isolation of the world. These societies maintain a high degree of autonomy and avoid permanent contact with the surrounding societies. Since 2000, this region has been the target of policies aimed to favor the access to world markets (timber, oil, hydroelectric project, and the construction of infrastructure within the frame of the regional integration project IIRSA. This paper analyzes this situation, which threatens the survival of the isolated peoples who live in the region and has led to migratory processes of some of them from Peru into Brazil, and the reordering of the indigenous territories in this border region. These migrations often result in tense situations that can lead to conflicts between isolated and contacted groups. This calls for new strategies by the Brazilian and Peruvian organizations responsible for the protection and safeguarding of their rights, and for a greater integration between the institutions of both countries.

Study on three dimensional seismic isolation system

International Nuclear Information System (INIS)

Morishita, Masaki; Kitamura, Seiji

2003-01-01

Japan Nuclear Cycle Development Institute (JNC) and Japan Atomic Power Company (JAPC) launched joint research programs on structural design and three-dimensional seismic isolation technologies, as part of the supporting R and D activities for the feasibility studies on commercialized fast breeder reactor cycle systems. A research project by JAPC under the auspices of the Ministry of Economy, Trade, and Industry (METI) with technical support by JNC is included in this joint study. This report contains the results of the research on the three-dimensional seismic isolation technologies, and the results of this year's study are summarized in the following five aspects. (1) Study on Earthquake Condition for Developing 3-dimensional Base Isolation System. The case study S2 is one of the maximum ground motions, of which the records were investigated up to this time. But a few observed near the fault exceed the case study S2 in the long period domain, depending on the fault length and conditions. Generally it is appropriate that the response spectra ratio (vertical/horizontal) is 0.6. (2) Performance Requirement for 3-dimensional Base Isolation System and Devices. Although the integrity map of main equipment/piping dominate the design criteria for the 3-dimensional base isolation system, the combined integrity map is the same as those of FY 2000, which are under fv=1Hz and over hv=20%. (3) Developing Targets and Schedule for 3-dimensional Isolation Technology. The target items for 3-dimensional base isolation system were rearranged into a table, and developing items to be examined concerning the device were also adjusted. A development plan until FY 2009 was made from the viewpoint of realization and establishment of a design guideline on 3-dimensional base isolation system. (4) Study on 3-dimensional Entire Building Base Isolation System. Three ideas among six ideas that had been proposed in FY2001, i.e., '3-dimensional base isolation system incorporating hydraulic

Life history, population viability, and the potential for local adaptation in isolated trout populations

Directory of Open Access Journals (Sweden)

K.J. Carim

2017-04-01

Full Text Available Habitat loss and fragmentation have caused population decline across taxa through impacts on life history diversity, dispersal patterns, and gene flow. Yet, intentional isolation of native fish populations is a frequently used management strategy to protect against negative interactions with invasive fish species. We evaluated the population viability and genetic diversity of 12 isolated populations of Oncorhynchus clarkii lewisi located on the Flathead Indian Reservation in Montana, USA. Length-structured integral projection models (IPMs were used to project population growth rate (lambda and its sensitivity to underlying vital rates and parameters. We examined relationships between lambda, genetic diversity, and habitat size and quality. Lambda ranged from 0.68 to 1.1 with 10 of 12 populations projected to be in decline. A sensitivity analysis of lambda with respect to projection matrix elements indicated that lambda was generally sensitive to changes in early life history stages (survival/growth, but patterns differed among populations. Another sensitivity analysis with respect to underlying model parameters showed highly consistent pattern across populations, with lambda being most sensitive to the slope of probability of maturity (estimated from published literature, generally followed by adult survival, and the slope of somatic growth rate (directly measured from each population. Lambda was not correlated with genetic diversity. For populations residing in small isolated streams (≤5 km of occupied habitat, lambda significantly increased with base flow discharge (r2=0.50, p<0.02. Our results highlight the potential importance of local adaptation for persistence of small, isolated populations. Specifically we saw evidence for higher probability of maturity at smaller sizes in the smallest, coldest isolated systems, increasing probability of persistence for these populations. Climate change threatens to further fragment populations of

49 CFR Appendix A to Part 611 - Description of Measures Used for Project Evaluation.

Science.gov (United States)

2010-10-01

...) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MAJOR CAPITAL INVESTMENT PROJECTS Pt. 611... project isolate the costs and benefits of the major transit investment. At a minimum, the baseline... investment in the new start project. Depending on the circumstances and through prior agreement with FTA, the...

Seismic proving test of process computer systems with a seismic floor isolation system

International Nuclear Information System (INIS)

Fujimoto, S.; Niwa, H.; Kondo, H.

1995-01-01

The authors have carried out seismic proving tests for process computer systems as a Nuclear Power Engineering Corporation (NUPEC) project sponsored by the Ministry of International Trade and Industry (MITI). This paper presents the seismic test results for evaluating functional capabilities of process computer systems with a seismic floor isolation system. The seismic floor isolation system to isolate the horizontal motion was composed of a floor frame (13 m x 13 m), ball bearing units, and spring-damper units. A series of seismic excitation tests was carried out using a large-scale shaking table of NUPEC. From the test results, the functional capabilities during large earthquakes of computer systems with a seismic floor isolation system were verified

Isolation plan for the southern end of the 313 Metal Fabrication Building

International Nuclear Information System (INIS)

Smith, D.S.

1997-02-01

The 313 Metal Fabrication Building was originally constructed as part of the Manhattan Project and underwent major remodeling and expansion in 1954. The building is divided into two sections that were separated by a fire wall. The first characterization of the 313(S) Building was conducted in 1995 to identify radiological, chemical, and other hazardous substances that may be encountered during the isolation activities. The intent of the isolation plan is to identify all known issues and reasonable solutions to these issues. Some issues will be solved during the building isolation activity, and other issues will remain unsolved until the actual demolition activity occurs

Project specific quality assurance plan for Project W-178, 219-S secondary containment

International Nuclear Information System (INIS)

Buckles, D.I.

1994-01-01

The scope of this Quality Assurance Program Plan (QAPP) is to provide a system of Quality Assurance reviews and verifications on the design, procurement and construction of the 219-S Secondary Containment Upgrade. The reviews and verifications will be on activities associated with design, procurement, and construction of the Secondary Containment Upgrade which includes, but is not limited to demolition, removal, new tank installation, tank 103 isolation, tank cell refurbishment, electrical, instrumentation, piping/tubing including supports, pump and valves, and special coatings. The full project scope is defined in the project Functional Design Criteria (FDC), SD-W178-FDC-001, and all activities must be in compliance with this FDC and related design documentation

Use of natural materials from Northern Russia for the isolation of radioactive wastes and spent nuclear fuel

International Nuclear Information System (INIS)

Komlev, V.N.

1998-01-01

The application of natural materials to the isolation of radioactive waste and spent nuclear fuel is being assessed, together with possible isolation technologies. The operational requirements for such materials are identified and a proposal for an inter-regional ecological and technological project is discussed. 39 refs

Proposed waste isolation pilot project (WIPP) and impacts in the state of New Mexico: a socio-economic analysis. Final report

International Nuclear Information System (INIS)

Cummings, R.D.; Burness, H.S.; Norton, R.D.

1981-04-01

This document is a final report for research conducted concerning the socio-economic impacts in the State of New Mexico that might attend the construction and operation of the proposed Waste Isolation Pilot Plant (WIPP). The proposed site for the WIPP, known as the Los Medanos site, is in Southeastern New Mexico's Eddy County, some 25 miles east of Carlsbad, New Mexico and some 40 miles from Hobbs, New Mexico, in adjacent Lea County. The purpose as set out in the US Department of Energy's environmental impact statements is for storage of TRU waste from the US defense program and the construction of a research and development area for experiments concerning the isolation of all types of nuclear waste in salt. The intended purpose of the study is to identify, measure (when possible) and assess the range of potential socio-economic impacts in the State that may be attributable to the WIPP. Every effort has been made by the authors to approach this task in an objective manner. In efforts to provide an objective analysis of the WIPP, however, particular attention was required in providing a comprehensive review of potential impacts. This means that however unlikely an impact might seem, the authors have purposely avoided pre-judging the potential magnitude of the impact and have applied their best efforts to measure it. On the other hnd, this study is not intended to provide a definitive calculation regarding the net balance of WIPP-related benefits and costs. To help ensure objectivity, two advisory boards, Technical Advisory Board and Public Advisory Board, were formed at the outset of the project for the purpose of providing periodic reviews of research efforts

Seismic isolation structure for pool-type LMFBR - isolation building with vertically isolated floor for NSSS

International Nuclear Information System (INIS)

Sakurai, A.; Shiojiri, H.; Aoyagi, S.; Matsuda, T.; Fujimoto, S.; Sasaki, Y.; Hirayama, H.

1987-01-01

The NSSS isolation floor vibration characteristics were made clear. Especially, the side support bearing (rubber bearing) is effective for horizontal floor motion restraint and rocking motion control. Seismic isolation effects for responses of the reactor components can be sufficiently expected, using the vertical seismic isolation floor. From the analytical and experimental studies, the following has been concluded: (1) Seismic isolation structure, which is suitable for large pool-type LMFBR, were proposed. (2) Seismic response characteristics of the seismic isolation structure were investigated. It was made clear that the proposed seismic isolation (Combination of the isolated building and the isolated NSSS floor) was effective. (orig./HP)

Review on recent advances in the analysis of isolated organelles

Czech Academy of Sciences Publication Activity Database

Satori, Ch. P.; Košťál, Vratislav; Arriaga, E. A.

2012-01-01

Roč. 753, NOV 13 (2012), s. 8-18 ISSN 0003-2670 R&D Projects: GA ČR(CZ) GBP206/12/G014 Institutional research plan: CEZ:AV0Z40310501 Keywords : organelle isolation * fluorescence * electrophoresis Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 4.387, year: 2012

The International Stripa Project: an overview

International Nuclear Information System (INIS)

Fairhurst, C.; Gera, F.; Gnirk, P.; Gray, M.; Stillborg, B.

1993-01-01

The International Stripa Project was a a cooperative research and development project among several member countries of the Nuclear Energy Agency of the Organization for Economic Cooperation and Development. The scientific and technical objectives of the project were to investigate several aspects of technology concerned with the feasibility and safety of disposal of long-lived, heat-generating radioactive waste at depth in granitic rocks. In particular, the Stripa Project addressed: 1) the development of instruments and procedures to characterize candidate repository sites; 2) the understanding and modelling of groundwater flow and solute transport in fractured crystalline rock; and 3) the design of engineered barriers capable of contributing to waste isolation by restricting groundwater flow in proximity to the waste containers and in the surrounding host rock. This overview summarizes the work focussed on natural barriers and engineered barriers. (author)

HIE-ISOLDE, the project and the physics opportunities

Energy Technology Data Exchange (ETDEWEB)

Borge, M.J.G. [ISOLDE, EP Department, CERN, Geneva 23 (Switzerland); Instituto de Estructura de la Materia, CSIC, Madrid (Spain); Riisager, K. [Aarhus University, Department of Physics and Astronomy, Aarhus C (Denmark)

2016-11-15

The ISOLDE facility at CERN offers the largest selection of ISOL beams today. The overall aim of the HIE-ISOLDE project is to enlarge the physics domains achievable with these beams, in particular by raising the maximum energy of post-accelerated beams to more than 10 MeV/u. An outline of the history of the project is followed by a succinct description of the superconducting linac chosen for acceleration and an overview of the parts of the project aiming to the improvement of the beam quality and intensity. Concrete examples are given of experiments that will be performed at HIE-ISOLDE. (orig.)

The Hel Peninsula – Smart Grid Pilot Project

Directory of Open Access Journals (Sweden)

Sławomir Noske

2014-12-01

Full Text Available The paper presents the scope and results of engineering, and the scope of Smart Grid deployment in the Hel Peninsula. The following functionalities will be described: Fault Detection, Isolation & Recovery – FDIR function, Integrated Volt/Var Control (IVVC function, advanced supervision of LV grid, including distributed energy resources. The paper contains implementation results and research findings, as well as preliminary cost-benefit analysis of the project. Moreover, since Smart Metering and Smart Grid projects are being deployed in the same region – the Hel Peninisula – the benefit achieved by merging the two projects will be explained.

Project finance and international energy development

International Nuclear Information System (INIS)

Pollio, G.

1998-01-01

This paper explores the preference for and the features unique to project finance, one of the favoured vehicles for funding energy development. Our main focus is on the interests of project sponsors, commercial banks and host governments. Inclusion of the latter reflects the fact host governments are often leading participants in primary energy and energy-related projects; more recently, they have come to use limited recourse structures to finance local infrastructure development. Traditional analyses, whilst providing useful insights into the interests of leading project participants, are incapable of isolation a single motive or set of motives that can comprehensively account for all of the features common to this form of debt. Within an options-theoretic framework, most of these ambiguities are resolved. Risk management, long recognised as one of the primary reasons for choosing project finance over rival debt structures, is affirmed as a key explanatory factor. One the other hand, options pricing theory provides a radically different perspective on how to project finance contributes to the realisation of these objectives. (author)

The projection of Inner Aspect in Vietnamese

Directory of Open Access Journals (Sweden)

Trang Phan

2013-06-01

Full Text Available Several semantic and syntactic distinctions, which have largely been neglected in the Vietnamese linguistic literature, are drawn together in this paper in a comparative context with other better-studied languages in order to indicate that Inner Aspect is projected within the VP shell and independently of the projection of Outer Aspect – a structural proposal originally advanced by Travis (2010. Overall, Vietnamese with its isolating character and rigid word order provides us with unusually direct evidence for an articulated VP structure.

The implementation of base isolation in the United States

International Nuclear Information System (INIS)

Kelly, J.M.

1993-01-01

The concept of base isolation as an innovative means of providing earthquake resistance to structural systems was met initially with a great deal of skepticism by the engineering community. Today, however, it is on the cutting edge of seismic-resistance engineering, as evidenced by the rapidly increasing number of buildings, both new construction and retrofit, using this earthquake-resistant technique. It is now generally accepted that a base-isolated building will perform better than a conventional fixed-base building in moderate or strong earthquakes. In the structures in which it has been used so far, the major benefit has been to reduce the effects of seismic forces on contents and internal equipment, more than justifying the increased cost of isolated construction. This review will mainly cover the development and application of base isolation to buildings in the US. The acceptance of this approach has been slow, but as a result of the 1989 Loma Prieta earthquake there is an increasing interest in its use for repair of buildings damaged in that earthquake and for the retrofit of historic buildings that are considered vulnerable to earthquake loading. Base isolation may play a major role in the future in projects as diverse as advanced nuclear reactors and public housing in developing countries

Mathematical programming and financial objectives for scheduling projects

CERN Document Server

Kimms, Alf

2001-01-01

Mathematical Programming and Financial Objectives for Scheduling Projects focuses on decision problems where the performance is measured in terms of money. As the title suggests, special attention is paid to financial objectives and the relationship of financial objectives to project schedules and scheduling. In addition, how schedules relate to other decisions is treated in detail. The book demonstrates that scheduling must be combined with project selection and financing, and that scheduling helps to give an answer to the planning issue of the amount of resources required for a project. The author makes clear the relevance of scheduling to cutting budget costs. The book is divided into six parts. The first part gives a brief introduction to project management. Part two examines scheduling projects in order to maximize their net present value. Part three considers capital rationing. Many decisions on selecting or rejecting a project cannot be made in isolation and multiple projects must be taken fully into a...

Solid-phase DNA isolation from food matrices using hydrophilic magnetic microspheres

Czech Academy of Sciences Publication Activity Database

Trachtová, Š.; Španová, A.; Tóth, J.; Prettl, Z.; Horák, Daniel; Gyenis, J.; Rittich, B.

2015-01-01

Roč. 94, April (2015), s. 375-381 ISSN 0960-3085 R&D Projects: GA ČR GAP206/12/0381 Institutional support: RVO:61389013 Keywords : DNA compaction * magnetic microspheres * DNA isolation Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.687, year: 2015

A Model of Project and Organisational Dynamics

Directory of Open Access Journals (Sweden)

Jenny Leonard

2012-04-01

Full Text Available The strategic, transformational nature of many information systems projects is now widely understood. Large-scale implementations of systems are known to require significant management of organisational change in order to be successful. Moreover, projects are rarely executed in isolation – most organisations have a large programme of projects being implemented at any one time. However, project and value management methodologies provide ad hoc definitions of the relationship between a project and its environment. This limits the ability of an organisation to manage the larger dynamics between projects and organisations, over time, and between projects. The contribution of this paper, therefore, is to use literature on organisational theory to provide a more systematic understanding of this area. The organisational facilitators required to obtain value from a project are categorised, and the processes required to develop those facilitators are defined. This formalisation facilitates generalisation between projects and highlights any time and path dependencies required in developing organisational facilitators. The model therefore has the potential to contribute to the development of IS project management theory within dynamic organisational contexts. Six cases illustrate how this model could be used.

Quality Management System at Construction Project: A Questionnaire Survey

OpenAIRE

P.P.Mane; J.R.Patil

2015-01-01

The best quality, time and cost are the important aspects of successful construction project which fulfills the main goal of construction industry. The quality management has to provide the environment within which related tools, techniques and procedures can be deployed effectively leading to operational success for a construction project. The role of quality management for a construction company is not an isolated activity, but intertwined with all the operational and managerial...

Refurbishment of isolation room and development of glove box for the DUPIC project in IMEF

International Nuclear Information System (INIS)

Baek, S. Y.; Park, J. J.; Lee, H. H.; Hong, K. P.; Yang, M. S.; Min, D. K.

2001-01-01

To perform R and D of DUPIC (Direct Use of Spent PWR Fuel in CANDU Reactors), the high-radioactive shielding facility is necessary. IMEF(Irradiated Material Examination Facility) in KAERI has the high-radioactive shielding facility and some R and D such that the spent PWR fuel can be burned again in a PHWR by direct re-fabrication into CANDU-compatible DUPIC fuel bundles, is being carried out using the manipulator attached to the hotcell-M6. Although many testing equipment are located and are being operated in hotcell, it is not possible to work personally inside the hotcell due to the high radioactive contaminant. When they are out of order, the cleaned one can be maintained and repaired using the renovated isolation room located over the hotcell-M6 and the new devised glove box located at service area. Some lead-sheets and the lead glasses were fixed on the wall of the isolation room to improve the shielding capability and the roof door of hotcell-M6 can be open remotely. To maintain and repair the equipment of hotcell, a working desk was constructed in the isolation room. The glove box was also made to withdraw the disordered equipment of hotcell through the rear door

Potential for long-term isolation by the Waste Isolation Pilot Plant disposal system

Energy Technology Data Exchange (ETDEWEB)

Bertram-Howery, S.G. (Sandia National Labs., Albuquerque, NM (USA)); Swift, P.N. (Tech. Reps., Inc., Albuquerque, NM (USA))

1990-06-01

The US Department of Energy's (DOE) Waste Isolation Pilot Plant (WIPP) must comply with EPA regulation 40 CFR Part 191, Subpart B, which sets environmental standards for radioactive waste disposal. The regulation, Environmental Radiation Protection Standards for Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes (hereafter referred to as the Standard), was vacated in 1987 by a Federal Court of Appeals and is underground revision. By agreement with the Sate of New Mexico, the WIPP project is evaluating compliance with the Standard as promulgated, in 1985 until a new regulation is available. This report summarizes the early-1990 status of Sandia National Laboratories' (SNL) understanding of the Project's ability to achieve compliance. The report reviews the qualitative and quantitative requirements for compliance, and identifies unknowns complicating performance assessment. It discusses in relatively nontechnical terms the approaches to resolving those unknowns, and concludes that SNL has reasonable confidence that compliance is achievable with the Standard as first promulgated. 46 refs., 7 figs.

[Effects of long-term isolation and anticipation of significant event on sleep: results of the project "Mars-520"].

Science.gov (United States)

Zavalko, I M; Rasskazova, E I; Gordeev, S A; Palatov, S Iu; Kovrov, G V

2013-01-01

The purpose of the research was to study effect of long-term isolation on night sleep. The data were collected during international ground simulation of an interplanetary manned flight--"Mars-500". The polysomnographic recordings of six healthy men were performed before, four times during and after 520-days confinement. During the isolation sleep efficiency and delta-latency decreased, while sleep latency increased. Post-hoc analysis demonstrate significant differences between background and the last (1.5 months before the end of the experiment) measure during isolation. Frequency of nights with low sleep efficiency rose on the eve of the important for the crew events (simulation of Mars landing and the end of the confinement). Two weeks after the landing simulation, amount of the nights with a low sleep efficiency significantly decreased. Therefore, anticipation of significant event under condition of long-term isolation might result in sleep worsening in previously healthy men, predominantly difficulties getting to sleep.

Deafblind people, communication, independence, and isolation.

Science.gov (United States)

Hersh, Marion

2013-10-01

This paper discusses issues related to communication, independence, and isolation for an understudied group of deaf people who also have visual impairments. The discussion is based on the experiences of 28 deafblind people in 6 different countries, obtained from interviews that were carried out as part of a larger research project on travel issues. However, the similarities in experiences between countries were stronger than the differences. In particular, barriers to communication and inadequate support, with resulting problems of isolation and depression, were found in all the countries. Equally, deafblind people in all the countries were interested in being involved in and contributing to society and supporting other people, particularly through organizations of blind and deafblind people. This runs counter to the tendency to present deafblind and other disabled people purely as recipients of support rather than also as active participants in society. However, there were some differences in the support available in the different countries.

Project of an integrated calibration laboratory of instruments at IPEN

International Nuclear Information System (INIS)

Barros, Gustavo Adolfo San Jose

2009-01-01

The Calibration Laboratory of Instruments of Instituto de Pesquisas Energeticas e Nucleares offers calibration services of radiation detectors used in radioprotection, diagnostic radiology and radiotherapy, for IPEN and for external facilities (public and private). One part of its facilities is located in the main building, along with other laboratories and study rooms, and another part in an isolated building called Bunker. For the optimization, modernization and specially the safety, the laboratories in the main building shall be transferred to an isolated place. In this work, a project of an integrated laboratory for calibration of instruments was developed, and it will be an expansion of the current Calibration Laboratory of Instruments of IPEN. Therefore, a series of radiometric monitoring of the chosen localization of the future laboratory was realized, and all staff needs (dimensions and disposition of the study rooms and laboratories) were defined. In this project, the laboratories with X ray equipment, alpha and beta radiation sources were located at an isolated part of the building, and the wall shielding was determined, depending on the use of each laboratory. (author)

Antifungal activity of indigenous Bacillus spp. isolated from soil

Directory of Open Access Journals (Sweden)

Bjelić Dragana Đ.

2017-01-01

Full Text Available Biocontrol using plant growth-promoting rhizobacteria (PGPR represents an alternative approach to disease management, since PGPR are known to promote growth and reduce diseases in various crops. Among the different PGPR, members of the genus Bacillus are prefered for most biotechnological uses due to their capability to form extremely resistant spores and produce a wide variety of metabolites with antimicrobial activity. The objective of this research was to identify antagonistic bacteria for management of the plant diseases. Eleven isolates of Bacillus spp. were obtained from the soil samples collected from different localities in the Province of Vojvodina. The antifungal activity of bacterial isolates against five fungal species was examined using a dual plate assay. Bacillus isolates exhibited the highest antifungal activity against Fusarium proliferatum, Fusarium oxysporum f. sp. cepae and Alternaria padwickii, while they had the least antagonistic effect on Fusarium verticillioides and Fusarium graminearum. Molecular identification showed that effective bacterial isolates were identified as Bacillus safensis (B2, Bacillus pumilus (B3, B11, Bacillus subtilis (B5, B7 and Bacillus megaterium (B8, B9. The highest antagonistic activity was exhibited by isolates B5 (from 39% to 62% reduction in fungal growth and B7 (from 40% to 71% reduction in fungal growth. These isolates of B. subtilis could be used as potential biocontrol agents of plant diseases. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. TR-31073

Clean development mechanism and off-grid small-scale hydropower projects: Evaluation of additionality

International Nuclear Information System (INIS)

Tanwar, Nitin

2007-01-01

The global climate change mitigation policies and their stress on sustainable development have made electrification of rural mountainous villages, using small hydro, an attractive destination for potential clean development mechanism (CDM) projects. This invariably involves judging the additionality of such projects. The paper suggests a new approach to judge the additionality of such stand-alone small hydropower projects. This has been done by breaking up additionality into two components: external and local. The external additionality is project developer dependent. For determining the local additionality, the paper takes into account the probability of a village getting electrified over a period of time, which is kept equal to the possible crediting period. This is done by defining an electrification factor (EF) whose value depends on the degree of isolation, financial constraints and institutional constraints encountered while electrifying a mountainous village. Using this EF, the additionality of a CDM project can be judged in a much easier and accurate way. The paper is based on the data and inputs gathered during site visits to many isolated villages located in the eastern Indian Himalayas

The Far-Infrared Properties of the Most Isolated Galaxies

Science.gov (United States)

Lisenfeld, U.; Verdes-Montenegro, L.; Sulentic, J.; Leon, S.; Espada, D.; Bergond, G.; García, E.; Sabater, J.; Santander-Vela, J. D.; Verley, S.

2007-05-01

A long-standing question in galaxy evolution involves the role of nature (self-regulation) vs. nurture (environment) on the observed properties (and evolution) of galaxies. A collaboration centreed at the Instituto de Astrofisica de Andalucia (Granada, Spain) is trying to address this question by producing a observational database for a sample of 1050 isolated galaxies from the catalogue of Karachentseva (1973) with the overarching goal being the generation of a "zero-point" sample against which effects of environment on galaxies can be assessed. The AMIGA (Analysis of the Interstellar Medium of Isolated Galaxies) database (see www.iaa.es/AMIGA.html) will include optical, IR and radio line and continuum measures. The galaxies in the sample represent the most isolated galaxies in the local universe. In the present contribution, we will present the project, as well as the results of an analysis of the far-infrared (FIR) and molecular gas properties of this sample.

Identification of factors that influence the stiffness of high-damping elastomer seismic isolation bearings

International Nuclear Information System (INIS)

Kulak, R.F.; Hughes, T.H.

1994-01-01

During the past decade, high-damping elastomer, steel-laminated seismic isolation bearings have gained acceptance as a device for isolating large buildings and structures from earthquake damage. In the United States, architectural engineering firms custom design isolators for each project and ten have the isolators manufactured by one of less than a hand-full of manufactures. The stiffness of the bearing is the single most important design parameter that the molded bearing must meet because it determines the fundamental frequency of the isolation system. This paper reports on recent research that examined several factors that cause real and potential variations to the stiffness of the bearing. The resulting changes to the fundamental frequency of the isolated structure are quantified for each factor. The following were examined: (1) dimensional tolerances, (2) frequency effects, (3) temperature effects, (4) cyclical effects, and (5) aging effects. It was found that geometric variations barely affect the stiffness whereas temperature variations greatly affect the stiffness

Geomechanical applications for the Waste Isolation Pilot Plant (WIPP) project

International Nuclear Information System (INIS)

Matalucci, R.V.; Hunter, T.O.

1981-01-01

The Waste Isolation Pilot Plant (WIPP) is a research and development facility in bedded salt addressing the technical issues associated with the demonstration of disposal of radioactive waste from the defense programs of the USA. The geomechanical program includes laboratory experimentation, constitutive model and computer code development, and in-situ experimentation. Various material models, including creep for salt, and techniques for predicting room response under thermal and mechanical loads have been developed and are being applied to experiment and facility designs. A Benchmark II study has been conducted to compare the capabilities of nine structural codes to predict response of underground configuration under ambient temperature and with a thermal load of 7.5 W/m 2 . Parametric studies are being conducted to evaluate optimum room configurations. A series of in situ experiments is the next step towards validating models and predictive techniques. These experiments will be conducted in a facility in southeastern New Mexico mined at a depth of 659 m

Modification of the ventilation system at Waste Isolation Pilot Plant (WIPP)

International Nuclear Information System (INIS)

Sethi, S.C.

1987-01-01

The WIPP (Waste Isolation Pilot Plant) Project near Carlsbad, New Mexico, is a research and development project sponsored by the US Department of Energy, designed to demonstrate the safe disposal of radioactive waste. A mine (repository) is being developed 2,150 feet below the surface in a thick salt bed, which will serve as the disposal medium. The underground ventilation system for the WIPP project was originally designed based on a fixed project scope. The design criteria and ventilation requirements were developed for the performance of various activities as then envisioned towards the achievement of this goal. However, in light of new information and actual site-specific experience at WIPP leading to a clearer definition of the scope-related programs and activities, it was realized that the existing ventilation system may need to be modified

WIPP Project Records Management Handbook

International Nuclear Information System (INIS)

1991-01-01

The Waste Isolation Pilot Plant (WIPP) Records Management Handbook provides the WIPP Project Records Management personnel with a tool to use to fulfill the requirements of the WIPP Records Program and direct their actions in the important area of records management. The handbook describes the various project areas involved in records management, and how they function. The handbook provides the requirements for Record Coordinators and Master Record Center (MRC) personnel to follow in the normal course of file management, records scheduling, records turnover, records disposition, and records retrieval. More importantly, the handbook provides a single reference which encompasses the procedures set fourth in DOE Order 1324.2A, ''Records Disposition'' ASME NQA-1, ''Quality Assurance Program Requirements for Nuclear Facilities'' and DOE-AL 5700.6B, ''General Operations Quality Assurance.'' These documents dictate how an efficient system of records management will be achieved on the WIPP Project

Identification of a Plasmid-Mediated Quinolone Resistance Gene in Salmonella Isolates from Texas Dairy Farm Environmental Samples.

Science.gov (United States)

Cummings, K J; Rodriguez-Rivera, L D; Norman, K N; Ohta, N; Scott, H M

2017-06-01

A recent increase in plasmid-mediated quinolone resistance (PMQR) has been detected among Salmonella isolated from humans in the United States, and it is necessary to determine the sources of human infection. We had previously isolated Salmonella from dairy farm environmental samples collected in Texas, and isolates were tested for anti-microbial susceptibility. Two isolates, serotyped as Salmonella Muenster, showed the discordant pattern of nalidixic acid susceptibility and intermediate susceptibility to ciprofloxacin. For this project, whole-genome sequencing of both isolates was performed to detect genes associated with quinolone resistance. The plasmid-mediated qnrB19 gene and IncR plasmid type were identified in both isolates. To our knowledge, this is the first report of PMQR in Salmonella isolated from food animals or agricultural environments in the United States. © 2016 Blackwell Verlag GmbH.

Decision management - projects subject to uncertainty

Directory of Open Access Journals (Sweden)

A.E. Paterson

2003-12-01

Full Text Available The human mind is normally unable to grasp more than five to nine aspects relating to the same decision circumstances simultaneously. It has been demonstrated that only between four and eight variables significantly affect return on engineering projects (at the 90% level irrespective of scale. The most powerful means of isolating these significant variables is by computer simulation. This is demonstrated through the application of the interactive CASPAR programme to a simulated mining project. The significant variables are separated into controllable, influence able and uncontrollable categories for decision and control purposes since the nature of the speculative risk differs. The managerial treatment of each category is discussed.

Review of relevant studies of isolated systems

DEFF Research Database (Denmark)

Hansen, L.H.; Lundsager, P.

2001-01-01

The report presents the results of a review of studies relating to integration of wind energy in isolated power supply systems, based on a systematic literature survey. The purpose of the study is to develop a methodology consisting of a set of guidelinesfor wind energy projects in isolated energy...... systems and a set of tools and models that are operational on an engineering level. The review is based on a literature search in the ETDE Energy Database with a main search covering the period 7/88 to 6/97 andsupplemented by partial update periods. A few newer references have been included in the review...... have been organised according to the following keywords: methods & guides, economics, concept ofapplication, system solutions, case studies, financial programmes, dedicated software tools. None of the found references presents methods or tools that contradict the philosophy of Risø's methodology...

Energy demand in an isolated community: Arixi/AM, Brazil; Demandas energeticas de uma comunidade isolada - Arixi/AM

Energy Technology Data Exchange (ETDEWEB)

Ferreira, Elen Jane de Abreu; Barbosa, Sonia Regina da Cal Seixas [Universidade Estadual de Campinas (FEM/UNICAMP), SP (Brazil). Fac. de Engenharia Mecanica. Programa de Pos-Graduacao em Planejamento de Sistemas Energeticos], e-mail: srcal@unicamp.br

2006-07-01

Isolated energy communities in the Amazon are known by not being integrated to the rest of the net country of generation and distribution of electric energy. Therefore, federal government proposes an equal electric energy distribution for everyone in the country in order to bring social and economic development, mainly to the isolated energy communities. In this context, the isolated Arixi community, a small village in the Amazon, is focus of the project 'Alternative Production Energy from Cell Fuel and Natural Gas in the Amazon State - CELCOMB', a partnership between Federal Amazon University and State University of Campinas, which has the objective of producing alternative energy from cell fuel and natural gas. The objective of this article is to analyze the energy aspects of the isolated community of Arixi in the Amazon, and also get to know its energy demand. To do so, this article is based on a master dissertation and also in community field research. So, despite of the fact that this article is part of a larger project, by analyzing energy data and nowadays demands of the community, we will be able to examine what are the real electric energy requirements of an isolated community in the Amazon. (author)

Fumonisins production potential of Fusarium verticillioides isolated from Serbian maize and wheat kernels

Directory of Open Access Journals (Sweden)

Krstović Saša Z.

2017-01-01

Full Text Available The production of fumonisins by potentially toxigenic Fusarium verticillioides isolates originating from Serbian maize and wheat kernels was tested in vitro. A total of six F. verticillioides isolates were incubated on yeast extract sucrose medium (YESA for 4 weeks at 25 °C in the dark. Their toxin production potential was tested by applying a modified HPLC method for determination of fumonisins in cereals, since the TLC method gave no results. Analyses were performed on a HPLC-FLD system after sample extraction from YESA and extract cleanup on a SPE column. Although the isolates were tested for fumonisin B1, B2 and B3, only fumonisin B1 was detected. The results showed that all tested isolates had toxigenic potential for fumonisin B1 production. The average fumonisin B1 production of the isolates ranged from 7 to 289 μg/kg, thus indicating a highly variable toxigenic potential among the isolates. Isolate 1282 expressed the highest toxigenic potential for fumonisin B1 production (289 μg/kg, while isolate 2533/A showed a questionable potential for fumonisin production (7 μg/kg. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. TR 31023

Systematics of Aedes Mosquito Project.

Science.gov (United States)

1984-01-01

Fever and Zika viruses . During a recent field trip to Cameroon and Kenya in the early part of 1983 numerous specimens were collected, mostly as reared...1942) isolated Yellow Fever virus is Aedes (Stejomyia) broeliae (Theobald) and is the common man-biting member of -th-e complex in East Africa. The...PERIOD COVERED Five Month Report Systematics of Aedes Mosquito Project August 1 - December 31, 1983 p - 6. PERFORMING ORG. REPORT NUMBER 7. AUTHOR(&) S

Role of uncertainty in the basalt waste isolation project

International Nuclear Information System (INIS)

Knepp, A.J.; Dahlem, D.H.

1989-01-01

The current national Civilian Radioactive Waste Management (CRWM) Program to select a mined geologic repository will likely require the extensive use of probabilistic techniques to quantify uncertainty in predictions of repository isolation performance. Performance of nonhomogeneous, geologic hydrologic, and chemical systems must be predicted over time frames of thousands of years and therefore will likely contain significant uncertainty. A qualitative assessment of our limited ability to interrogate the site in a nondestructive manner coupled with the early stage of development in the pertinent geosciences support this statement. The success of the approach to incorporate what currently appears to be an appreciable element of uncertainty into the predictions of repository performance will play an important role in acquiring a license to operate and in establishing the level of safety associated with the concept of long-term geologic storage of nuclear waste. This paper presents a brief background on the Hanford Site and the repository program, references the sources that establish the legislative requirement to quantify uncertainties in performance predictions, and summarized the present and future program at the Hanford Site in this area. The decision to quantify significant sources of uncertainties has had a major impact on the direction of the site characterization program here at Hanford. The paper concludes with a number of observations on the impacts of this decision

YUCCA MOUNTAIN PROJECT - A BRIEFING -

International Nuclear Information System (INIS)

2003-01-01

This report has the following articles: Nuclear waste--a long-term national problem; Spent nuclear fuel; High-level radioactive waste; Radioactivity and the environment; Current storage methods; Disposal options; U.S. policy on nuclear waste; The focus on Yucca Mountain; The purpose and scope of the Yucca Mountain Project; The approach for permanently disposing of waste; The scientific studies at Yucca Mountain; The proposed design for a repository at Yucca Mountain; Natural and engineered barriers would work together to isolate waste; Meticulous science and technology to protect people and the environment; Licensing a repository; Transporting waste to a permanent repository; The Environmental Impact Statement for a repository; Current status of the Yucca Mountain Project; and Further information available on the Internet

Quality assurance during fabrication of high-damping rubber isolation bearings

Energy Technology Data Exchange (ETDEWEB)

Way, D.; Greaves, W.C. [Base Isolation Consultants, Inc., San Francisco, CA (United States)

1995-12-01

Successful implementation of a high-damping rubber (HDR) base isolation project requires the application of Quality Assurance/Quality Control (QA/QC) methodology through all phases of the bearing fabrication process. HDR base isolation bearings must be fabricated with uniform physical characteristics while being produced in large quantities. To satisfy this requirement, manufacturing processes must be controlled. Prototype tests that include dynamic testing of small samples of rubber are necessary. Stringent full scale bearing testing must be carried out prior to beginning production, during which manufacturing is strictly regulated by small rubber sample and production bearing testing. All such activities should be supervised and continuously inspected by independent and experienced QA/QC personnel.

Interdisciplinary physics research in the Japanese Hadron Project

International Nuclear Information System (INIS)

Yamazaki, Toshimitsu.

1990-09-01

The Japanese Hadron Project (JHP) is a large future plan of interdisciplinary and international scope, aimed at basic physics research by creating and using various secondary unstable particle beams such as mesons, muons, neutrons and accelerated exotic nuclei. It comprises a high-intensity proton linac of 1 GeV, a compressor/stretcher ring and an ISOL/accelerator to deliver beams to MESON, NEUTRON and EXOTIC NUCLEI arena's. In addition, as the present ongoing project, we are pushing KAON arena based on the KEK 12 GeV proton synchrotron. The present paper describes the scientific motivation and technological bases for this future project as well as the presently going pre-JHP research activities. (author)

Project Physics Text 3, The Triumph of Mechanics.

Science.gov (United States)

Harvard Univ., Cambridge, MA. Harvard Project Physics.

Mechanical theories are presented in this unit of the Project Physics text for senior high students. Collisions, Newton's laws, isolated systems, and Leibniz' concept are discussed, leading to conservation of mass and momentum. Energy conservation is analyzed in terms of mechanical energy, heat energy, steam engines, Watt's engine, Joule's…

Lack of reproductive isolation between the Western and Eastern phylogroups of the tench

Czech Academy of Sciences Publication Activity Database

Lajbner, Zdeněk; Kohlmann, K.; Linhart, O.; Kotlík, Petr

2010-01-01

Roč. 2010, č. 3 (2010), s. 289-300 ISSN 0960-3166 R&D Projects: GA MŠk LC06073 Institutional research plan: CEZ:AV0Z50450515 Keywords : Tench * Phylogroups * Reproductive isolation Subject RIV: EG - Zoology Impact factor: 3.609, year: 2010

Nova isolates noise to quieten stations

International Nuclear Information System (INIS)

Milner, G.J.; Frank, L.D.

1993-01-01

This paper reviews a technique developed by Nova Corp., to help isolate and measure the acoustic power of individual components in a pipeline compressor and pumping station. The procedure calculates the sound pressure levels of each piece of equipment independently. Based on these measurements, a prediction can be made of the effect of various types of noise treatment techniques on the overall sound levels currently generated or proposed in a future project. This paper describes the equipment to measure the sound levels, techniques for actually measuring the compressor station or equipment area, and techniques used to generate a remediation plan

BWIP-RANDOM-SAMPLING, Random Sample Generation for Nuclear Waste Disposal

International Nuclear Information System (INIS)

Sagar, B.

1989-01-01

1 - Description of program or function: Random samples for different distribution types are generated. Distribution types as required for performance assessment modeling of geologic nuclear waste disposal are provided. These are: - Uniform, - Log-uniform (base 10 or natural), - Normal, - Lognormal (base 10 or natural), - Exponential, - Bernoulli, - User defined continuous distribution. 2 - Method of solution: A linear congruential generator is used for uniform random numbers. A set of functions is used to transform the uniform distribution to the other distributions. Stratified, rather than random, sampling can be chosen. Truncated limits can be specified on many distributions, whose usual definition has an infinite support. 3 - Restrictions on the complexity of the problem: Generation of correlated random variables is not included

Star Formation Intensities Of Non-Isolated Galaxies With The Califa Survey

Science.gov (United States)

Morales Vargas, Abdías; Torres-Papaqui, Juan Pablo; Rosales-Ortega, Fernando Fabián; Sánchez, Sebastián F.; Chow-Martínez, Marcel; Ortega-Minakata, René Alberto; Romero-Cruz, Fernando J.; Trejo-Alonso, Josué de Jesús; Neri-Larios, Daniel Marcos; Robleto-Orús Aitor, Carlos

2017-08-01

Poster presented at the conference Galaxy Evolution Across Time, 12-16 June, Paris, France. The influence of interactions on the star formation (SF) is investigated by studying a sample of 34 CALIFA survey non-isolated galaxies. We use the instantaneous star formation rate intensity (SFRI) obtained from the Halpha recombination line emission normalized by a unit of projected area. We explore the SFRI, stellar mass and stellar age annulus structures (split by morphology group), also for a control population of star-forming isolated galaxies observed with the CALIFA survey likewise. By morphology groups, the SF efficiency of early type spirals (ETSs) results magnified likely because of angular momentum loss. The SFRI of the non-isolated sample is then compared with that one of the isolated sample. It is found statistically and moderately enhanced in the non-isolated sample by a factor of at most 2. We also find the SFRI as to be a function of the degree of tidal perturbation what might consequently suggest interactions as to facilitate the gas transport to central regions. Contrasting behaviors of the SFRI structures, a gradual quench with clear outer presence of SF (isolated sample) while a steeper decrease from the center with poor SFRIs outwards (non-isolated one) are found. Similitudes in a variety of stellar population properties support the closeness of companions as to be the cause of the SFRI differences between samples.

New method of plant mitochondria isolation and sub-fractionation for proteomic analyses

Czech Academy of Sciences Publication Activity Database

Hájek, Tomáš; Honys, David; Čapková, Věra

2004-01-01

Roč. 167, č. 3 (2004), s. 389-395 ISSN 0168-9452 R&D Projects: GA MŠk LZ1K03018 Institutional research plan: CEZ:AV0Z5038910 Keywords : plant mitochondria isolation * sub-fractionation * protein analysis Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.389, year: 2004

CIGEO: some reasons to trust the project soundness

International Nuclear Information System (INIS)

2013-07-01

This article outlines why the SFEN believes in the soundness of the CIGEO project. It outlines four reasons for a favourable impression: all countries have chosen the geological deposit, the client (the ANDRA) is a public body, Cigeo is the result of a large collective effort, and the Cigeo project is permanently controlled and assessed by irrefutable bodies. Two benefits of geological deposit are outlined: it has a totally passive safety, and it allows wastes to be isolated from biosphere for many years. The Cigeo project is presented as sufficiently advanced and the industrial phase can now start. The article states that there is no impact on neighbouring populations, and that nuclear power stations avoid the important chemical pollution of fossil fuel power stations. Finally, the project is presented as being a strong factor of development for the region in terms of jobs

Isolated galaxies

International Nuclear Information System (INIS)

Einasto, Maret

1990-01-01

To test for the possible presence of really isolated galaxies, which form a randomly distributed population in voids, we compare the distribution of most isolated galaxies in an observed sample with distributions of the same number of random points using the nearest neighbour test. The results show that the random population of really isolated galaxies does not exist - even the most isolated galaxies are connected with systems of galaxies, forming their outlying parts. (author)

Dredging Research, Volume 3, No. 3. DNA Technology to Impact Dredged Material Projects through Faster, More Accurate Testing Methods

National Research Council Canada - National Science Library

McDonald, Allison

2000-01-01

.... Most people associate DNA with criminal cases and paternity testing, but thanks to research projects such as the Human Genome Project, which has isolated and identified thousands of genes, many...

The ZaP Flow Z-Pinch Project - Final Technical Report

Energy Technology Data Exchange (ETDEWEB)

Shumlak, Uri [Univ. of Washington, Seattle, WA (United States); Nelson, Brian A. [Univ. of Washington, Seattle, WA (United States)

2013-12-31

The ZaP Flow Z-Pinch Project is a project to extend the performance of the flow Z-pinch experiment at the University of Washington to investigate and isolate the relevant physics of the stabilizing effect of plasma flow. Experimental plasmas have exhibited an enhanced stability under certain operating parameters which generate a flow state (axial flows in Z-pinches and VH mode in tokamaks). Flow has also been suggested as the stabilizing mechanism in astrophysical jets.

Report on a Program Evaluation of a Telephone Assisted Parenting Support Service for Families Living in Isolated Rural Areas.

Science.gov (United States)

Cann, Warren; Rogers, Helen; Worley, Greg

2003-01-01

This brief report evaluates a pilot project to deliver a telephone supported, self-directed parenting program to isolated families. The aim of the project was to promote the competence and confidence of parents experiencing early difficulties. Significant improvements were noted in child behavior, parenting style, parental depression, anxiety, and…

Projective Method for Generic Sensor Fusion Problem

International Nuclear Information System (INIS)

Rao, N.S.V.

1999-01-01

In a multiple sensor system, each sensor produces an output which is related to the desired feature according to a certain probability distribution. We propose a fuser that combines the sensor outputs to more accurately predict the desired feature. The fuser utilizes the lower envelope of regression curves of sensors to project the sensor with the least error at each point of the feature space. This fuser is optimal among all projective fusers and also satisfies the isolation property that ensures a performance at least as good as the best sensor. In the case the sensor distributions are not known, we show that a consistent estimator of this fuser can be computed entirely based on a training sample. Compared to linear fusers, the projective fusers provide a complementary performance. We propose two classes of metafusers that utilize both linear and projectives fusers to perform at least as good as the best sensor as well as the best fuser

An analysis of stripping to isolated analog resonances

International Nuclear Information System (INIS)

Pessoa, E.F.; Toledo Piza, A.F.R. de.

1983-04-01

The Feshbach projection formalism is used to calculate the form factors for the (d,n) stripping process to isolated analog resonances. These are used in a standard DWBA stripping calculation in which the radial integration over all space is accomplished by including outerspace contributions evaluated along the complex contours of Vincent and Fortune. It turns out that the shape and magnitude of the predicted cross section is quite insensitive to the continuum proton wave emanating from the resonant residual state. (Author) [pt

Outline of OMEGA project

International Nuclear Information System (INIS)

Umezawa, Hirokazu

1989-01-01

Attention has been paid to the research and development on the group partition and annihilation disposal technology which separates long life radioactive nuclides, rare stable nuclides and so on in high level radioactive wastes and utilizes those for respective suitable uses, or which searches for the possibility of promoting the nuclear disintegration of long life radioactive nuclides, as the basic research aiming at the further development of atomic energy. It was named 'OMEGA project' and its promotion has been carried out. The outline of the project and the international circumstances surrounding it are described. In the high level radioactive wastes generated from the reprocessing of spent nuclear fuel, the alpha and beta-gamma radionuclides having long life are contained. Consequently, it is necessary to isolate them from human environment for very long period, and the basic method is the glass solidification and the disposal in deep strata, therefore the technical development has been advanced. The OMEGA project was decided in October, 1988, and the course of the research carried out so far, the international cooperation and the subjects of research and development are reported. (K.I.)

The changes in perception of visual illusions during long-term isolation

Czech Academy of Sciences Publication Activity Database

Šikl, Radovan; Šimeček, Michal; Lukavský, Jiří

2009-01-01

Roč. 2009, č. 38 (2009), s. 31-32 ISSN 0301-0066. [European Conference on Visual Perception. 24.08.2009-28.08.2009, Regensburg] R&D Projects: GA ČR GA406/09/2003 Institutional research plan: CEZ:AV0Z70250504 Keywords : long-term isolation * geometrical illusions * perspective Subject RIV: AN - Psychology http://www.perceptionweb.com/abstract.cgi?id=v090766

Using multimedia technology to help combat the negative effects of protective isolation on patients: the Open Window project--an engineering challenge.

LENUS (Irish Health Repository)

Hegarty, F

2012-02-01

The Open Window project was established with the aim of creating a "virtual window" for each patient who is confined to protective isolation due to treatment for illness. This virtual window as developed provides a range of media or experiences. This paper describes the approach taken to the system design and discusses initial experiences with implementing such a system in a critical care setting. The system design was predicated on two guiding principles. Firstly it should be intuitive to use and the technology used to create the virtual window hidden from patient view. Secondly the system must be able to be installed at the point of care in a way that delivers the experience under the patient\\'s control, without compromising the function or safety of the clinical environment. Patient acceptance of the system is being measured as part of an on-going trial and at this interim phase of data analysis 100% (n=55) of participants in the intervention group have reported that the technology was easy to use. We conclude that the system as designed and installed is an effective, robust and reliable system upon which to base a multimedia interventions in a critical care room.

Geological challenges in radioactive waste isolation: Third worldwide review

International Nuclear Information System (INIS)

Witherspoon Editor, P.A.; Bodvarsson Editor, G.S.

2001-01-01

The broad range of activities on radioactive waste isolation that are summarized in Table 1.1 provides a comprehensive picture of the operations that must be carried out in working with this problem. A comparison of these activities with those published in the two previous reviews shows the important progress that is being made in developing and applying the various technologies that have evolved over the past 20 years. There are two basic challenges in perfecting a system of radioactive waste isolation: choosing an appropriate geologic barrier and designing an effective engineered barrier. One of the most important developments that is evident in a large number of the reports in this review is the recognition that a URL provides an excellent facility for investigating and characterizing a rock mass. Moreover, a URL, once developed, provides a convenient facility for two or more countries to conduct joint investigations. This review describes a number of cooperative projects that have been organized in Europe to take advantage of this kind of a facility in conducting research underground. Another critical development is the design of the waste canister (and its accessory equipment) for the engineered barrier. This design problem has been given considerable attention in a number of countries for several years, and some impressive results are described and illustrated in this review. The role of the public as a stakeholder in radioactive waste isolation has not always been fully appreciated. Solutions to the technical problems in characterizing a specific site have generally been obtained without difficulty, but procedures in the past in some countries did not always keep the public and local officials informed of the results. It will be noted in the following chapters that this procedure has caused some problems, especially when approval for a major component in a project was needed. It has been learned that a better way to handle this problem is to keep all

Geological challenges in radioactive waste isolation: Third worldwide review

Energy Technology Data Exchange (ETDEWEB)

Witherspoon Editor, P.A.; Bodvarsson Editor, G.S.

2001-12-01

The broad range of activities on radioactive waste isolation that are summarized in Table 1.1 provides a comprehensive picture of the operations that must be carried out in working with this problem. A comparison of these activities with those published in the two previous reviews shows the important progress that is being made in developing and applying the various technologies that have evolved over the past 20 years. There are two basic challenges in perfecting a system of radioactive waste isolation: choosing an appropriate geologic barrier and designing an effective engineered barrier. One of the most important developments that is evident in a large number of the reports in this review is the recognition that a URL provides an excellent facility for investigating and characterizing a rock mass. Moreover, a URL, once developed, provides a convenient facility for two or more countries to conduct joint investigations. This review describes a number of cooperative projects that have been organized in Europe to take advantage of this kind of a facility in conducting research underground. Another critical development is the design of the waste canister (and its accessory equipment) for the engineered barrier. This design problem has been given considerable attention in a number of countries for several years, and some impressive results are described and illustrated in this review. The role of the public as a stakeholder in radioactive waste isolation has not always been fully appreciated. Solutions to the technical problems in characterizing a specific site have generally been obtained without difficulty, but procedures in the past in some countries did not always keep the public and local officials informed of the results. It will be noted in the following chapters that this procedure has caused some problems, especially when approval for a major component in a project was needed. It has been learned that a better way to handle this problem is to keep all

Base Isolation for Seismic Retrofitting of a Multiple Building Structure: Design, Construction, and Assessment

Directory of Open Access Journals (Sweden)

Massimiliano Ferraioli

2017-01-01

Full Text Available The paper deals with the seismic retrofit of a multiple building structure belonging to the Hospital Centre of Avellino (Italy. At first, the paper presents the preliminary investigations, the in situ measurements and laboratory tests, and the seismic assessment of the existing fixed-base structures. Having studied different strategies, base isolation proved to be the more appropriate, also for the possibility offered by the geometry of the building to easily create an isolation interface at the ground level. The paper presents the design project, the construction process, and the details of the isolation intervention. Some specific issues of base isolation for seismic retrofitting of multiple building structures were lightened. Finally, the seismic assessment of the base-isolated building was carried out. The seismic response was evaluated through nonlinear time-history analysis, using the well-known Bouc-Wen model as the constitutive law of the isolation bearings. For reliable dynamic analyses, a suite of natural accelerograms compatible with acceleration spectra of Italian Code was first selected and then applied along both horizontal directions. The results were finally used to address some of the critical issues of the seismic response of the base-isolated multiple building structure: accidental torsional effects and potential poundings during strong earthquakes.

Antibiotic Properties of the endophytic Streptomyces Spp. Isolated from the Leaves of Myanmar Medicinal Plants

International Nuclear Information System (INIS)

Aye Pe; Mar Mar Nyein; Win Maung

2002-02-01

Three medicinal plants of Myanmar are selected in the study of endophytic microorganisms and are taxonomically classified and identified to be Sa-ba-lin (Cymbopogon citratus Stapf.), Shazaungtinga- neah (Euphorbia splendens Bojer. ex Hooker) and Ma-shaw (Sauropus grandifolius Pax. and Hoffm.). The screening of endophytic microorganisms is performed according to the ISP method (International Streptomyces Projects 1993). The morphological and physicochemical properties of isolated strains are studied and identified to be the Genus Streptomyces. The test of apparent antimicrobial activity of isolated Streptomyces is done on 18 strains of pathogenic bacteria. It is found that the isolated endophytic Sireptomyces showed the significant antibacterial activity on most of the test organisms. (author)

The Beijing ISOL initial conceptual design report

International Nuclear Information System (INIS)

Cui, Baoqun; Gao, Yuan; Ge, Yucheng; Guo, Zhiyu; Li, Zhihong; Liu, Weiping; Peng, Shixiang; Peng, Zhaohua; Wang, Zhi; Yan, Sha; Ye, Yanlin; Zeng, Sheng; Zhang, Guohui; Zhu, Feng

2013-01-01

Highlights: • Peking University and China Institute of Atomic Energy are proposing to construct a facility called “Beijing ISOL”. • Beijing ISOL is aimed at both basic science and application goals. • Beijing ISOL is the double driver system, namely reactor driving (RD) and intense deuteron-beam driving (IDD). • Multi-beam, multi-energy and multi-terminal will be used to meet the users’ requirements. -- Abstract: Peking University (PKU) and China Institute of Atomic Energy (CIAE) are jointly proposing to construct a large science facility, temporarily called “Beijing ISOL”. This facility aims at both basic science and application goals, and is based on the double driver system, namely reactor driving and intense deuteron-beam driving. On the basic science side, the radioactive ion beams produced from the isotope separation online (ISOL) device will be used to study the new physics and technologies at the limit of nuclear stability. On the other side regarding to the applications, the facility will be devoted to material research for the nuclear energy system by using typically the intense neutron and ion beams. In the whole process of design, construction and operation, an opening policy will be pursued, and the domestic and international cooperation will be emphasized. Through this project, a joint research and education mode will be established

Final Hanford Site Transuranic (TRU) Waste Characterization Qualit Assurance Project Plan

International Nuclear Information System (INIS)

GREAGER, T.M.

1999-01-01

The Transuranic Waste Characterization Quality Assurance Program Plan required each U.S. Department of Energy (DOE) site that characterizes transuranic waste to be sent the Waste Isolation Pilot Plan that addresses applicable requirements specified in the quality assurance project plan (QAPP)

Characterization of probiotic Lactobacillus spp. isolates from commercial fermented milks

OpenAIRE

Farahmand, Nasim

2015-01-01

The aim of this project was to study the identity of probiotic lactobacilli in fermented milk products from the United Kingdom/European markets during their survival during shelf-life. This in vitro study was also aimed at undertaking studies on some of the physiological probiotic criteria, such as resistance to stomach/intestine conditions and also possible functional properties of the isolates, such as antimicrobial activities, antibiotic resistance/susceptibility and antibiotic resistance ...

Round robin testing of thermal conductivity reference materials

International Nuclear Information System (INIS)

Hulstrom, L.C.; Tye, R.P.; Smith, S.E.

1985-07-01

The Basalt Waste Isolation Project (BWIP), operated by Rockwell Hanford Operations, has a need to determine the thermal properties of basalt in the region being considered for a nuclear waste repository in basalt. Experimental data on thermal conductivity and its variation with temperature are information required for the characterization of basalt. To establish thermal conductivity values for the reference materials, an interlaboratory measurements program was undertaken. The program was planned to meet the objectives of performing an experimental characterization of the new stock and providing a detailed analysis of the results such that reference values of thermal conductivity could be determined. This program of measurements of the thermal conductivity of Pyrex 7740 and Pyroceram 9606 has produced recommended values that are within +- 1% of those accepted previously. These measurements together with those of density indicate that the present lots of material are similar to those previously available. Pyrex 7740 and Pyroceram 9606 can continue to be used with confidence as thermal conductivity reference materials for studies on rocks and minerals and other materials of similar thermal conductivity. The uncertainty range for Pyrex 7740 and Pyroceram 9606 up to 300 0 C is +- 10.3% and +- 5.6%, respectively. This range is similar to that indicated for the previously recommended values proposed some 18 years ago. It would appear that the overall state of the art in thermal conductivity measurements for materials in this range has changed little in the intervening years. The above uncertainties, which would have been greater had not three data sets been eliminated, are greater than those which are normally claimed for each individual method. Analyses of these differences through refinements in techniques and additional measurements to higher temperatures are required. 13 refs., 7 figs., 4 tabs

Experimental Study of Vibration Isolation Characteristics of a Geometric Anti-Spring Isolator

Directory of Open Access Journals (Sweden)

Lixun Yan

2017-07-01

Full Text Available In order to realize low-frequency vibration isolation, a novel geometric anti-spring isolator consisting of several cantilever blade springs are developed in this paper. The optimal design parameters of the geometric anti-spring isolator for different nonlinear geometric parameters are theoretically obtained. The transmissibility characteristic of the geometric anti-spring isolator is investigated through mathematical simulation. A geometric anti-spring isolator with a nonlinear geometric parameter of 0.92 is designed and its vibration isolation performance and nonlinearity characteristic is experimentally studied. The experiment results show that the designed isolator has good low-frequency vibration isolation performance, of which the initial isolation frequency is less than 3.6 Hz when the load weight is 21 kg. The jump phenomena of the response of the isolator under linear frequency sweep excitation are observed, and this result demonstrates that the geometric anti-spring isolator has a complex nonlinearity characteristics with the increment of excitation amplitude. This research work provides a theoretical and experimental basis for the application of the nonlinear geometric anti-spring low-frequency passive vibration isolation technology in engineering practice.

Sensing and collecting radioactive materials as a project to teach engineering design

International Nuclear Information System (INIS)

Drake, D.; Majdi, T.; Strack, J.

2015-01-01

The remote detection and isolation of radioactive materials is both a challenging engineering design project and a relevant issue given modern nuclear circumstances. This project is used in the undergraduate capstone class of the Engineering Physics Department at McMaster University to teach students engineering design. This paper discusses the course outline and learning outcomes of the students who took the course over the 2014-2015 academic year. (author)

Sensing and collecting radioactive materials as a project to teach engineering design

Energy Technology Data Exchange (ETDEWEB)

Drake, D.; Majdi, T.; Strack, J., E-mail: draked2@mcmaster.ca [McMaster University, Hamiltion, ON (Canada); and others

2015-07-01

The remote detection and isolation of radioactive materials is both a challenging engineering design project and a relevant issue given modern nuclear circumstances. This project is used in the undergraduate capstone class of the Engineering Physics Department at McMaster University to teach students engineering design. This paper discusses the course outline and learning outcomes of the students who took the course over the 2014-2015 academic year. (author)

Detection of the Velocity Shear Effect on the Spatial Distributions of the Galactic Satellites in Isolated Systems

Science.gov (United States)

Lee, Jounghun; Choi, Yun-Young

2015-02-01

We report a detection of the effect of the large-scale velocity shear on the spatial distributions of the galactic satellites around the isolated hosts. Identifying the isolated galactic systems, each of which consists of a single host galaxy and its satellites, from the Seventh Data Release of the Sloan Digital Sky Survey and reconstructing linearly the velocity shear field in the local universe, we measure the alignments between the relative positions of the satellites from their isolated hosts and the principal axes of the local velocity shear tensors projected onto the plane of sky. We find a clear signal that the galactic satellites in isolated systems are located preferentially along the directions of the minor principal axes of the large-scale velocity shear field. Those galactic satellites that are spirals, are brighter, are located at distances larger than the projected virial radii of the hosts, and belong to the spiral hosts yield stronger alignment signals, which implies that the alignment strength depends on the formation and accretion epochs of the galactic satellites. It is also shown that the alignment strength is quite insensitive to the cosmic web environment, as well as the size and luminosity of the isolated hosts. Although this result is consistent with the numerical finding of Libeskind et al. based on an N-body experiment, owing to the very low significance of the observed signals, it remains inconclusive whether or not the velocity shear effect on the satellite distribution is truly universal.

DETECTION OF THE VELOCITY SHEAR EFFECT ON THE SPATIAL DISTRIBUTIONS OF THE GALACTIC SATELLITES IN ISOLATED SYSTEMS

International Nuclear Information System (INIS)

Lee, Jounghun; Choi, Yun-Young

2015-01-01

We report a detection of the effect of the large-scale velocity shear on the spatial distributions of the galactic satellites around the isolated hosts. Identifying the isolated galactic systems, each of which consists of a single host galaxy and its satellites, from the Seventh Data Release of the Sloan Digital Sky Survey and reconstructing linearly the velocity shear field in the local universe, we measure the alignments between the relative positions of the satellites from their isolated hosts and the principal axes of the local velocity shear tensors projected onto the plane of sky. We find a clear signal that the galactic satellites in isolated systems are located preferentially along the directions of the minor principal axes of the large-scale velocity shear field. Those galactic satellites that are spirals, are brighter, are located at distances larger than the projected virial radii of the hosts, and belong to the spiral hosts yield stronger alignment signals, which implies that the alignment strength depends on the formation and accretion epochs of the galactic satellites. It is also shown that the alignment strength is quite insensitive to the cosmic web environment, as well as the size and luminosity of the isolated hosts. Although this result is consistent with the numerical finding of Libeskind et al. based on an N-body experiment, owing to the very low significance of the observed signals, it remains inconclusive whether or not the velocity shear effect on the satellite distribution is truly universal

Multilocus Sequence Typing Scheme versus Pulsed-Field Gel Electrophoresis for Typing Mycobacterium abscessus Isolates

Science.gov (United States)

Machado, Gabriel Esquitini; Matsumoto, Cristianne Kayoko; Chimara, Erica; Duarte, Rafael da Silva; de Freitas, Denise; Palaci, Moises; Hadad, David Jamil; Lima, Karla Valéria Batista; Lopes, Maria Luiza; Ramos, Jesus Pais; Campos, Carlos Eduardo; Caldas, Paulo César; Heym, Beate

2014-01-01

Outbreaks of infections by rapidly growing mycobacteria following invasive procedures, such as ophthalmological, laparoscopic, arthroscopic, plastic, and cardiac surgeries, mesotherapy, and vaccination, have been detected in Brazil since 1998. Members of the Mycobacterium chelonae-Mycobacterium abscessus group have caused most of these outbreaks. As part of an epidemiological investigation, the isolates were typed by pulsed-field gel electrophoresis (PFGE). In this project, we performed a large-scale comparison of PFGE profiles with the results of a recently developed multilocus sequence typing (MLST) scheme for M. abscessus. Ninety-three isolates were analyzed, with 40 M. abscessus subsp. abscessus isolates, 47 M. abscessus subsp. bolletii isolates, and six isolates with no assigned subspecies. Forty-five isolates were obtained during five outbreaks, and 48 were sporadic isolates that were not associated with outbreaks. For MLST, seven housekeeping genes (argH, cya, glpK, gnd, murC, pta, and purH) were sequenced, and each isolate was assigned a sequence type (ST) from the combination of obtained alleles. The PFGE patterns of DraI-digested DNA were compared with the MLST results. All isolates were analyzable by both methods. Isolates from monoclonal outbreaks showed unique STs and indistinguishable or very similar PFGE patterns. Thirty-three STs and 49 unique PFGE patterns were identified among the 93 isolates. The Simpson's index of diversity values for MLST and PFGE were 0.69 and 0.93, respectively, for M. abscessus subsp. abscessus and 0.96 and 0.97, respectively, for M. abscessus subsp. bolletii. In conclusion, the MLST scheme showed 100% typeability and grouped monoclonal outbreak isolates in agreement with PFGE, but it was less discriminative than PFGE for M. abscessus. PMID:24899019

Understanding socioeconomic aspects of risk perception: Progress report, FY-1987: Working draft

International Nuclear Information System (INIS)

Liebow, E.B.; Fawcett-Long, J.A.; Terrill, E.S.

1987-11-01

This report summarizes progress to date in understanding the issue of risk perception and its implications for the suitability of the Hanford Site in eastern Washington as a location for an underground radioactive waste repository. It presents some observations about the causes, consequences and processes of risk perception gained from a review of the professional literature. It also contains an extensive working bibliography of useful reference materials, and a compilation of abstracts from selected articles that are felt to be of particular relevance to the BWIP licensing and institutional support efforts. 293 refs

Management of delayed nuclear power plant projects

International Nuclear Information System (INIS)

2005-01-01

The IAEA assists the management of organizations responsible for Nuclear Power Plant Projects with significant delays with respect to the originally scheduled commercial operation. Several Member States have Nuclear Power Plant Projects with delays of five or more years with respect to the originally scheduled commercial operation. The degree of conformance with original construction schedules shows large variations due to several issues, including financial, economic and public opinion factors. Solving the special difficulties related with a delayed NPP project is problematic and dependent on the particular country situation. However it is not regarded as an isolated national problem but as a significant issue with a number of difficulties shared by several Member States. The IAEA collects information and supports the management of delayed NPP projects by identifying main common issues, gathering available experience and addressing specific needs. On this background the IAEA is in the position to provide unique impartial assistance based upon best international practices. This enables Member States to maintain readiness for resuming the project construction when the conditions permit and to strengthen management's abilities for the completion of the project. The IAEA's service is tailored to the needs and requirements of the requesting organization, implemented on-site by international experts and addresses areas such as project control measures, human resources, updating to technological and regulatory requirements, project data, nuclear safety review, physical protection and nuclear security and preparation to resume project construction and operation

Community College Economics Instruction: Results from a National Science Foundation Project

Science.gov (United States)

Maier, Mark; Chi, W. Edward

2016-01-01

The principal investigator of a National Science Foundation project, "Economics at Community Colleges," surveyed community college economics faculty and organized workshops, webinars, and regional meetings to address community college faculty isolation from new ideas in economics and economics instruction. Survey results, combined with…

The SSM/PMAD automated test bed project

Science.gov (United States)

Lollar, Louis F.

1991-01-01

The Space Station Module/Power Management and Distribution (SSM/PMAD) autonomous subsystem project was initiated in 1984. The project's goal has been to design and develop an autonomous, user-supportive PMAD test bed simulating the SSF Hab/Lab module(s). An eighteen kilowatt SSM/PMAD test bed model with a high degree of automated operation has been developed. This advanced automation test bed contains three expert/knowledge based systems that interact with one another and with other more conventional software residing in up to eight distributed 386-based microcomputers to perform the necessary tasks of real-time and near real-time load scheduling, dynamic load prioritizing, and fault detection, isolation, and recovery (FDIR).

Seismic isolation rubber bearings for nuclear facilities

International Nuclear Information System (INIS)

Fujita, Takafumi

1991-01-01

This paper describes results of biaxial breaking tests by compression and shear and by tension and shear for seismic isolation rubber bearings with bolted-type connections. The bearings used in the tests were low-damping rubber bearings, high-damping rubber bearings, and lead-rubber bearings. Three modes of failure of the bolted-type bearings were observed in the tests. They are the breaking failure by tension and shear; the breaking failure by compression and shear; and the buckling failure by compression and shear. The first and the second modes of failures are almost independent of the types and the sizes of the bearings. The breaking conditions of those failure modes are described in the axial-stress-shear-strain plane. This expression is useful for the evaluation of safety margins of the bearings. The paper outlines the basic design of the nuclear-grade bearings which were used for large-scale rubber bearing tests in a research project for seismic isolation of FBR plants. It also discusses the protection method against aging and the quality control which are important for implementation. (orig./HP)

Seismic isolation rubber bearings for nuclear facilities

International Nuclear Information System (INIS)

Fujita, Takafumi

1989-01-01

This paper describes results of biaxial breaking tests by compression and shear and by tension and shear for seismic isolation rubber bearings with bolted-type connections. The bearings used in the tests were low-damping rubber bearings, high-damping rubber bearings, and lead-rubber bearings. Three modes of failure of the bolted-type bearings were observed in the tests. They are the breaking failure by tension and shear; the breaking failure by compression and shear; and the buckling failure by compression and shear. The first and the second modes of failures are almost independent of the types and the sizes of the bearings. The breaking conditions of those failure modes are described in the axial stress-shear strain plane. This expression is useful for the evaluation of safety margins of the bearings. The paper outlines the basic design of the nuclear-grade bearings which were used for large-scale rubber bearing tests in a research project for seismic isolation of fast breeder reactor (FBR) plants. The paper also discusses the protection method against aging and the quality control which are important for implementation

The heterogeneity of socially isolated older adults: a social isolation typology.

Science.gov (United States)

Machielse, Anja

2015-01-01

Recent statistics show a growing number of older adults who are living alone and are socially isolated. It is against this background that, in recent years, many interventions have been developed to address social isolation among the elderly. Evaluative studies show that most interventions are hardly effective, though. An important reason for this is the heterogeneity of the socially isolated. This article offers insight into this heterogeneity by presenting a typology with different profiles of socially isolated older adults and the intervention implications of this typology. The typology is derived from an extensive qualitative study on socially isolated elderly individuals in the Netherlands. The typology imposes some degree of order to a diversity of circumstances, ambitions, and possibilities of the socially isolated elderly, thereby deepening the understanding of the heterogeneity of this population. The definition of social isolation used in this study starts from a societal angle of incidence, namely the current policy context of Western European welfare states, in which governments emphasize the importance of independence and self-reliance of their citizens. Developed from that perspective, the typology provides a theoretical basis for applying interventions aimed at increasing self-reliance of social isolated elderly. This perspective on social isolation also has consequences for the way in which the effectiveness of interventions to alleviate social isolation is assessed.

Are isolated wetlands groundwater recharge hotspots?

Science.gov (United States)

Webb, A.; Wicks, C. M.; Brantley, S. T.; Golladay, S. W.

2017-12-01

Geographically isolated wetlands (GIWs) are a common landscape feature in the mantled karst terrain of the Dougherty Plain physiographic district in Southwestern Georgia. These wetlands support a high diversity of obligate/facultative wetland flora and fauna, including several endangered species. While the ecological value of these wetlands is well documented, the hydrologic effects of GIWs on larger watershed processes, such as water storage and aquifer recharge, are less clear. Our project seeks to understand the spatial and temporal variation in recharge across GIWs on this mantled karst landscape. In particular, our first step is to understand the role of isolated wetlands (presumed sinkholes) in delivering water into the underlying aquifer. Our hypothesis is that many GIWs are actually water-filled sinkholes and are locations of focused recharge feeding either the underlying upper Floridan aquifer or the nearby creeks. If we are correct, then these sinkholes should exhibit "drains", i.e., conduits into the limestone bedrock. Thus, the purposes of our initial study are to image the soil-limestone contact (the buried epikarstic surface) and determine if possible subsurface drains exist. Our field work was conducted at the Joseph W Jones Ecological Research Center. During the dry season, we conducted ground penetrating radar (GPR) surveys as grids and lines across a large wetland and across a field with no surface expression of a wetland or sinkhole. We used GPR (200 MHz antenna) with 1-m spacing between antenna and a ping rate of 1 ping per 40 centimeters. Our results show that the epikarstic surface exhibits a drain underneath the wetland (sinkhole) and that no similar feature was seen under the field, even though the survey grid and spacing were similar. As our project progresses, we will survey additional wetlands occurring across varying soil types to determine the spatial distribution between surface wetlands and subsurface drains.

In situ detection, isolation, and physiological properties of a thin filamentous microorganism abundant in methanogenic granular sludges: a novel isolate affiliated with a clone cluster, the green non-sulfur bacteria, subdivision I.

Science.gov (United States)

Sekiguchi, Y; Takahashi, H; Kamagata, Y; Ohashi, A; Harada, H

2001-12-01

We previously showed that very thin filamentous bacteria affiliated with the division green non-sulfur bacteria were abundant in the outermost layer of thermophilic methanogenic sludge granules fed with sucrose and several low-molecular-weight fatty acids (Y. Sekiguchi, Y. Kamagata, K. Nakamura, A. Ohashi, H. Harada, Appl. Environ. Microbiol. 65:1280-1288, 1999). Further 16S ribosomal DNA (rDNA) cloning-based analysis revealed that the microbes were classified within a unique clade, green non-sulfur bacteria (GNSB) subdivision I, which contains a number of 16S rDNA clone sequences from various environmental samples but no cultured representatives. To investigate their function in the community and physiological traits, we attempted to isolate the yet-to-be-cultured microbes from the original granular sludge. The first attempt at isolation from the granules was, however, not successful. In the other thermophilic reactor that had been treating fried soybean curd-manufacturing wastewater, we found filamentous microorganisms to outgrow, resulting in the formation of projection-like structures on the surface of granules, making the granules look like sea urchins. 16S rDNA-cloning analysis combined with fluorescent in situ hybridization revealed that the projections were comprised of the uncultured filamentous cells affiliated with the GNSB subdivision I and Methanothermobacter-like cells and the very ends of the projections were comprised solely of the filamentous cells. By using the tip of the projection as the inoculum for primary enrichment, a thermophilic, strictly anaerobic, filamentous bacterium, designated strain UNI-1, was successfully isolated with a medium supplemented with sucrose and yeast extract. The strain was a very slow growing bacterium which is capable of utilizing only a limited range of carbohydrates in the presence of yeast extract and produced hydrogen from these substrates. The growth was found to be significantly stimulated when the strain was

EPR project construction cost control

International Nuclear Information System (INIS)

Duflo, D.; Pouget-Abadie, X.; Dufour, A.; Kauffmann, G.

2001-01-01

The EPR project is now managed by EDF in cooperation with the German Utilities. The main engineering activities for this period are related to the preparation of construction project management, deepening of some safety issues, definition of the project technical reference. The EPR project concerns the so-called reference unit, that is an isolated first-off unit, with unit electrical power of about 1500 MW. The construction costs evaluated are those of the nuclear island, the conventional island, site facilities, installation work and the administrative buildings. The EPR project construction cost evaluation method applies to all the equipment installed and commissioned. It requires the availability of a preliminary project detailed enough to identify the bill of quantities. To these quantities are then assigned updated unit prices that are based either on cost bases for similar and recent facilities or taken from request for quotation for similar equipment or result from gains due to contractual conditions benefiting from simplifications in the functional and technical specifications. The input and output data are managed in a model that respects the breakdown on which the evaluation method is based. The structural organization of this method reflects a functional breakdown on the one hand (nuclear island, conventional island, common site elements) and on the other hand a breakdown according to equipment or activity (civil engineering, mechanics, electricity, instrumentation and control). This paper discusses the principle and the method of construction cost evaluation carried out, the cost data base and input and output parameters as well as results and oncoming cost analysis tasks. (author)

Genome-wide differentiation in closely related populations: the roles of selection and geographic isolation

Czech Academy of Sciences Publication Activity Database

Safran, R. J.; Scordato, E. S. C.; Wilkins, M. R.; Hubbard, J. K.; Jenkins, B. R.; Albrecht, Tomáš; Flaxman, S. M.; Karaardic, H.; Vortman, Y.; Lotem, A.; Nosil, P.; Pap, P.; Shen, S.; Chan, S.-F.; Parchman, T. L.; Kane, N. C.

2016-01-01

Roč. 25, č. 16 (2016), s. 3865-3883 ISSN 0962-1083 R&D Projects: GA MŠk(CZ) LH14045 Institutional support: RVO:68081766 Keywords : climate variability * climate variability * genotyping by sequencing * population genetics * reproductive isolation * speciation Subject RIV: EG - Zoology Impact factor: 6.086, year: 2016

Russian neo-revisionist strategy and the Eurasian Project

Directory of Open Access Journals (Sweden)

Ruslan Dzarasov

2017-03-01

Full Text Available The article is focused on the real meaning of the Eurasian Integration Project for East–West relations. The author departs from Sakwa’s treatment of Russian strategy as neo-revisionist. It does not aspire to change the current world order while trying to make the West observe its national interests within the existing framework. This perspective is treated in the article from the standpoint of world-systems analysis. The Eurasian Project is understood as a reaction of the Russian state to the failure of the neoliberal attempt to integrate into the world economy and the international security system. The two great trade mega-unions—the Trans-Pacific Partnership (TPP and the Trans-Atlantic Partnership—are seen as geoeconomic bolt clamps, which put Russia under enormous pressure. The Russian strategy in the Ukrainian and Syrian crises is designed to find the way out of strategic isolation. The Eurasian Union is expected by the Russian ruling elite to be an important tool to forestall the isolation of the country and secure her economic, military and international security.

Whole genome sequencing of Mycobacterium tuberculosis SB24 isolated from Sabah, Malaysia

Directory of Open Access Journals (Sweden)

Noraini Philip

2016-09-01

Full Text Available Mycobacterium tuberculosis (M. tuberculosis is the causative agent of tuberculosis (TB that causes millions of death every year. We have sequenced the genome of M. tuberculosis isolated from cerebrospinal fluid (CSF of a patient diagnosed with tuberculous meningitis (TBM. The isolated strain was referred as M. tuberculosis SB24. Genomic DNA of the M. tuberculosis SB24 was extracted and subjected to whole genome sequencing using PacBio platform. The draft genome size of M. tuberculosis SB24 was determined to be 4,452,489 bp with a G + C content of 65.6%. The whole genome shotgun project has been deposited in NCBI SRA under the accession number SRP076503.

Environmental Impact Statement: Waste Isolation Pilot Plant (WIPP): Executive summary

International Nuclear Information System (INIS)

1980-10-01

The purpose of this document is to provide a summary of the environmental impact statement for the Waste Isolation Pilot Plant (WIPP) project. The Draft Environmental Impact Statement for the WIPP was published by the US Department of Energy (DOE) in April 1979. This document was reviewed and commented on by members of the general public, private organizations, and governmental agencies. The Final Environmental Impact Statement was subsequently published in October, 1980. This summary is designed to assist decision-maker and interested individuals in reviewing the material presented in the environmental impact statement for the WIPP project. To make this material widely available, this summary is published in both Spanish and English. Additional, more detailed information concerning the environmental and safety consequences of the WIPP project is available in the Final Environmental Impact Statement. Written comments and public hearing comments on the Draft Environmental Impact Statement are available for review. 27 refs., 4 figs., 7 tabs

Multilocus sequence typing scheme versus pulsed-field gel electrophoresis for typing Mycobacterium abscessus isolates.

Science.gov (United States)

Machado, Gabriel Esquitini; Matsumoto, Cristianne Kayoko; Chimara, Erica; Duarte, Rafael da Silva; de Freitas, Denise; Palaci, Moises; Hadad, David Jamil; Lima, Karla Valéria Batista; Lopes, Maria Luiza; Ramos, Jesus Pais; Campos, Carlos Eduardo; Caldas, Paulo César; Heym, Beate; Leão, Sylvia Cardoso

2014-08-01

Outbreaks of infections by rapidly growing mycobacteria following invasive procedures, such as ophthalmological, laparoscopic, arthroscopic, plastic, and cardiac surgeries, mesotherapy, and vaccination, have been detected in Brazil since 1998. Members of the Mycobacterium chelonae-Mycobacterium abscessus group have caused most of these outbreaks. As part of an epidemiological investigation, the isolates were typed by pulsed-field gel electrophoresis (PFGE). In this project, we performed a large-scale comparison of PFGE profiles with the results of a recently developed multilocus sequence typing (MLST) scheme for M. abscessus. Ninety-three isolates were analyzed, with 40 M. abscessus subsp. abscessus isolates, 47 M. abscessus subsp. bolletii isolates, and six isolates with no assigned subspecies. Forty-five isolates were obtained during five outbreaks, and 48 were sporadic isolates that were not associated with outbreaks. For MLST, seven housekeeping genes (argH, cya, glpK, gnd, murC, pta, and purH) were sequenced, and each isolate was assigned a sequence type (ST) from the combination of obtained alleles. The PFGE patterns of DraI-digested DNA were compared with the MLST results. All isolates were analyzable by both methods. Isolates from monoclonal outbreaks showed unique STs and indistinguishable or very similar PFGE patterns. Thirty-three STs and 49 unique PFGE patterns were identified among the 93 isolates. The Simpson's index of diversity values for MLST and PFGE were 0.69 and 0.93, respectively, for M. abscessus subsp. abscessus and 0.96 and 0.97, respectively, for M. abscessus subsp. bolletii. In conclusion, the MLST scheme showed 100% typeability and grouped monoclonal outbreak isolates in agreement with PFGE, but it was less discriminative than PFGE for M. abscessus. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Prevalence of isolated systolic hypertension (ISH) in Slovene hypertensive patients: insights from the "Quality of Healthcare in Slovenia" project.

Science.gov (United States)

Pal, Marjetka; Ferk, Polonca; Leskošek, Brane; Krajnc, Ivan; Pajntar, Marjan

2015-12-01

The aim of the present study was mainly to evaluate age- and gender-dependent isolated systolic hypertension (ISH) prevalence before and during antihypertensive treatment, and to evaluate pulse pressure (PP) distributions during antihypertensive treatment in almost 20,000 Slovene hypertensive patients. The study was conducted as part of the "Quality of Healthcare in Slovenia" project, in agreement with the National Medical Ethics Committee of the Republic of Slovenia. Appropriate statistical analyses and evaluations were performed. The prevalence of ISH before the treatment was 19.6 % (17.0 % for men and 21.4 % for women) and it was significantly (p < 0.001) higher during the treatment (29.6 %; 26.4 % for men and 31.9 % for women). The mean PP before the treatment for the whole study patient sample was (71.2 ± 16.9) mmHg and was significantly (p < 0.001) reduced during the treatment to (57.4 ± 12.5) mmHg. With regard to high ISH in treated Slovene hypertensive patients, quality of ISH control may not be optimal and should be improved. On the other hand, the adequate arterial hypertension (AH) control (systolic blood pressure (SBP) < 140 mmHg and diastolic blood pressure (DBP) < 90 mmHg) was achieved in 55.6 % of patients. Our observations may have useful therapeutic implications in the management of AH, particularly ISH in the elderly.

Reinvestigation into Closure Predictions of Room D at the Waste Isolation Pilot Plant

Energy Technology Data Exchange (ETDEWEB)

Reedlunn, Benjamin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2016-10-01

Room D was an in-situ, isothermal, underground experiment conducted at theWaste Isolation Pilot Plant between 1984 and 1991. The room was carefully instrumented to measure the horizontal and vertical closure immediately upon excavation and for several years thereafter. Early finite element simulations of salt creep around Room D under predicted the vertical closure by 4.5×, causing investigators to explore a series of changes to the way Room D was modeled. Discrepancies between simulations and measurements were resolved through a series of adjustments to model parameters, which were openly acknowledged in published reports. Interest in Room D has been rekindled recently by the U.S./German Joint Project III and Project WEIMOS, which seek to improve the predictions of rock salt constitutive models. Joint Project participants calibrate their models solely against laboratory tests, and benchmark the models against underground experiments, such as room D. This report describes updating legacy Room D simulations to today’s computational standards by rectifying several numerical issues. Subsequently, the constitutive model used in previous modeling is recalibrated two different ways against a suite of new laboratory creep experiments on salt extracted from the repository horizon of the Waste Isolation Pilot Plant. Simulations with the new, laboratory-based, calibrations under predict Room D vertical closure by 3.1×. A list of potential improvements is discussed.

Reinvestigation into Closure Predictions of Room D at the Waste Isolation Pilot Plant

Energy Technology Data Exchange (ETDEWEB)

Reedlunn, Benjamin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2016-09-27

Room D was an in-situ, isothermal, underground experiment conducted at the Waste Isolation Pilot Plant between 1984 and 1991. The room was carefully instrumented to measure the horizontal and vertical closure immediately upon excavation and for several years thereafter. Early finite element simulations of salt creep around Room D under-predicted the vertical closure by 4.5×, causing investigators to explore a series of changes to the way Room D was modeled. Discrepancies between simulations and measurements were resolved through a series of adjustments to model parameters, which were openly acknowledged in published reports. Interest in Room D has been rekindled recently by the U.S./German Joint Project III and Project WEIMOS, which seek to improve the predictions of rock salt constitutive models. Joint Project participants calibrate their models solely against laboratory tests, and benchmark the models against underground experiments, such as room D. This report describes updating legacy Room D simulations to today’s computational standards by rectifying several numerical issues. Subsequently, the constitutive model used in previous modeling is recalibrated two different ways against a suite of new laboratory creep experiments on salt extracted from the repository horizon of the Waste Isolation Pilot Plant. Simulations with the new, laboratory-based, calibrations under-predict Room D vertical closure by 3.1×. A list of potential improvements is discussed.

Separation process design for isolation and purification of natural products

DEFF Research Database (Denmark)

Malwade, Chandrakant R.

Natural products are defined as secondary metabolites produced by plants and form a vast pool of compounds with unlimited chemical and functional diversity. Many of these secondary metabolites are high value added chemicals that are frequently used as ingredients in food, cosmetics, pharmaceuticals...... and other consumer products. Therefore, process technology towards industrial scale production of such high value chemicals from plants has significant value. Natural products can be obtained in pure form via synthetic or semi-synthetic route, but due to their complicated nature these methods have not been...... developed to the extent of industrial production for majority of natural products. Thus, isolation and purification of such natural products from plants is the most viable way to obtain natural products in pure form. This PhD project is mainly concerned with the design of separation process to isolate...

Design and methods of a social network isolation study for reducing respiratory infection transmission: The eX-FLU cluster randomized trial

Directory of Open Access Journals (Sweden)

Allison E. Aiello

2016-06-01

Conclusions/significance: We identified a feasible study design for testing the impact of isolation from social networks in a university setting. These data provide an unparalleled opportunity to address questions about isolation and infection transmission, as well as insights into social networks and behaviors among college-aged students. Several important lessons were learned over the course of this project, including feasible isolation durations, the need for extensive organizational efforts, as well as the need for specialized programmers and server space for managing survey and smartphone data.

Hospitals learn their collective power: an isolation gown success story.

Science.gov (United States)

Kressel, Amy B; McVey, Jennie L; Miller, Joan M; Fish, Lauren L

2011-02-01

We describe an investigation and improvement project designed to provide comfortable, affordable, fluid-resistant isolation gowns in response to inadequate compliance with gown use. Infection control and purchasing departments determined number of gowns used, cost/gown, and contract information for our laundry service. We investigated disposable gown options. During a conference call for a multihospital project, we learned that 4 local hospitals all used the same laundry service and that all were dissatisfied with the quality of the reusable gowns. The 4 hospitals resolved to meet with the hospital laundry service to negotiate as a group. In preparation, we both investigated laundry services in neighboring cities and reviewed Centers for Disease Control and Prevention and Occupational Safety and Health Administration isolation gown requirements. Confronted with its major customers acting collectively, the laundry service agreed to identify gowns by age, bring gowns to Occupational Safety and Health Administration compliance, mark grids so gowns could be removed after 75 washes, add 6,000 new gowns, and remove 6,000 old gowns. The cost increase was 3.75¢/gown. After the changeover was complete, reports of fluid leaking through gowns stopped. We saved $187,000 by keeping reusable gowns. When we tried to provide comfortable, affordable, fluid-resistant isolation gowns, we encountered 2 barriers: our city had only 1 hospital laundry service, and disposable gowns were costly. We solved the problem through unusual collaboration: internal (Infection Control and Purchasing) and external (with otherwise competing hospitals). Collaboration and knowledge sharing led to accountability: the hospital to its staff and budget and the laundry service to the hospitals. Copyright © 2011 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

Isolation and characterization of mesenchymal stem cell population entrapped in bone marrow collection sets

Czech Academy of Sciences Publication Activity Database

Dvořáková, J.; Hrubá, A.; Velebný, V.; Kubala, Lukáš

2008-01-01

Roč. 32, č. 9 (2008), s. 1116-1125 ISSN 1065-6995 R&D Projects: GA ČR(CZ) GA305/08/1704 Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702 Keywords : bone marrow * cell isolation * differentiation Subject RIV: BO - Biophysics Impact factor: 1.619, year: 2008

A note on isolate domination

Directory of Open Access Journals (Sweden)

Ismail Sahul Hamid

2016-04-01

Full Text Available A set $S$ of vertices of a graph $G$ such that $\\left\\langle S\\right\\rangle$ has an isolated vertex is called an \\emph{isolate set} of $G$. The minimum and maximum cardinality of a maximal isolate set are called the \\emph{isolate number} $i_0(G$ and the \\emph{upper isolate number} $I_0(G$ respectively. An isolate set that is also a dominating set (an irredundant set is an $\\emph{isolate dominating set} \\ (\\emph{an isolate irredundant set}$. The \\emph{isolate domination number} $\\gamma_0(G$ and the \\emph{upper isolate domination number} $\\Gamma_0(G$ are respectively the minimum and maximum cardinality of a minimal isolate dominating set while the \\emph{isolate irredundance number} $ir_0(G$ and the \\emph{upper isolate irredundance number} $IR_0(G$ are the minimum and maximum cardinality of a maximal isolate irredundant set of $G$. The notion of isolate domination was introduced in \\cite{sb} and the remaining were introduced in \\cite{isrn}. This paper further extends a study of these parameters.   

Communication between hospitals and isolated aboriginal community health clinics.

Science.gov (United States)

Mackenzie, G; Currie, B J

1999-04-01

This study described the communication dynamics, identified problems and recommended changes to improve patient follow-up and communication between Royal Darwin Hospital (RDH) and isolated Aboriginal community health clinics (CHC) in the Northern Territory (NT). In 1995, staff interviews were conducted and an audit of isolated Aboriginal patients' RDH discharge summaries (DS). Eighteen per cent of RDH DSs never arrived in CHCs. DSs were often prepared late and more likely to be in CHC records if written on time and if the referral source was specified. Interviews revealed discontent between CHCs and RDH regarding: communication, DS documentation, the supply of discharge medication, as well as different hospital and community perceptions of Aboriginies' reliability to carry a DS and CHC desire for patients to be given DSs at discharge. Aboriginal patients should be given a DS at discharge and resident medical officers should be educated as to the function and importance of the DS. In 18 months following this study, RDH appointed unit-based Aboriginal health workers and a policy was produced for written communication between hospital and CHCs, as well as a discharge planning manual for Aboriginal communities. Projects investigating communication between hospitals and isolated Aboriginal clinics and patient follow-up may result in significant policy changes concerning these processes.

Comparative study of aerial transmission lines and underground isolated on gas

International Nuclear Information System (INIS)

Quesada Jimenez, Marco Esteban

2012-01-01

A comparison was made of aerial power lines and underground isolated on gas. Growing electric demand has given way to debate the lines transmission. Multiple discussions have generated about its application, however, the energy must be supplied and this process leads to the search for more efficient methods. The theory has covered the most important design criteria of the airlines and an introduction to the little known transport lines isolated on gas. The process of manufacturing, installation and operation are studied within the scope of the project. Count information is included in the main aspects of calculation relating to power transmission. Besides, the planning of the optimal route nominal calculations, load flow and power losses are focused as well as magnetic field strengths and finally economic analysis. (author) [es

Isolation and antibiotic susceptibility testing of rapidly-growing mycobacteria from grassland soils

Czech Academy of Sciences Publication Activity Database

Kyselková, Martina; Chroňáková, Alica; Němec, Jan; Kotrbová, Lucie; Elhottová, Dana

2013-01-01

Roč. 3, č. 1 (2013), s. 76-80 ISSN 1338-5178 R&D Projects: GA ČR GAP504/10/2077; GA MŠk LC06066; GA MŠk(CZ) EE2.3.30.0032 Grant - others:GA JU(CZ) GAJU 04-142/2010/P Institutional support: RVO:60077344 Keywords : mycobakterium isolation and cultivation * grassland soil * antibiotic resistance Subject RIV: EE - Microbiology, Virology

Isolation of non-heprin-binding and heparin-binding proteins of boar prostate

Czech Academy of Sciences Publication Activity Database

Maňásková, Pavla; Liberda, J.; Tichá, M.; Jonáková, Věra

2002-01-01

Roč. 770, - (2002), s. 137-143 ISSN 1570-0232. [International Symposium /2./ - Separation in the BioSciences. Praha, 17.09.2001-20.09.2001] R&D Projects: GA ČR GA303/99/0357; GA ČR GV524/96/K162 Institutional research plan: CEZ:AV0Z5052915 Keywords : isolation * prostatic proteins * heparin Subject RIV: CE - Biochemistry Impact factor: 1.913, year: 2002

Preliminary report for analysis of genome wide mutations from four ciprofloxacin resistant B. anthracis Sterne isolates generated by Illumina, 454 sequencing and microarrays for DHS

Energy Technology Data Exchange (ETDEWEB)

Jaing, Crystal [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Vergez, Lisa [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hinckley, Aubree [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Thissen, James [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gardner, Shea [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); McLoughlin, Kevin [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jackson, Paul [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ellingson, Sally [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hauser, Loren [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Brettin, Tom [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Fofanov, Viacheslav [Eureka Genomics, Hercules, CA (United States); Koshinsky, Heather [Eureka Genomics, Hercules, CA (United States); Fofanov, Yuriy [Univ. of Houston, TX (United States)

2011-06-21

The objective of this project is to provide DHS a comprehensive evaluation of the current genomic technologies including genotyping, Taqman PCR, multiple locus variable tandem repeat analysis (MLVA), microarray and high-throughput DNA sequencing in the analysis of biothreat agents from complex environmental samples. As the result of a different DHS project, we have selected for and isolated a large number of ciprofloxacin resistant B. anthracis Sterne isolates. These isolates vary in the concentrations of ciprofloxacin that they can tolerate, suggesting multiple mutations in the samples. In collaboration with University of Houston, Eureka Genomics and Oak Ridge National Laboratory, we analyzed the ciprofloxacin resistant B. anthracis Sterne isolates by microarray hybridization, Illumina and Roche 454 sequencing to understand the error rates and sensitivity of the different methods. The report provides an assessment of the results and a complete set of all protocols used and all data generated along with information to interpret the protocols and data sets.

Exotic nuclei arena in Japanese Hadron Project

International Nuclear Information System (INIS)

Nomura, T.

1990-04-01

A description is given on the radioactive beam facility proposed as one of the research arenas in Japanese Hadron Project. The facility consists of a 1 GeV proton linac, an isotope separator on-line (ISOL) and a series of heavy-ion (HI) linacs. Various exotic nuclei produced by 1 GeV proton beam mainly via spallation processes of a thick target, are mass-separated by the ISOL with a high mass-resolving power and are injected into the HI linac with the energy of 1 keV/u. The acceleration is made in three stages using different types of linacs, i.e., split-coaxial RFQ. Interdigital-H, and Alvarez, the maximum energy in each stage being 0.17, 1.4 and 6.5 MeV/u, respectively. A few examples of scientific interests realized in this facility will be briefly discussed. (author)

The numerical computation of seismic fragility of base-isolated Nuclear Power Plants buildings

International Nuclear Information System (INIS)

Perotti, Federico; Domaneschi, Marco; De Grandis, Silvia

2013-01-01

Highlights: • Seismic fragility of structural components in base isolated NPP is computed. • Dynamic integration, Response Surface, FORM and Monte Carlo Simulation are adopted. • Refined approach for modeling the non-linearities behavior of isolators is proposed. • Beyond-design conditions are addressed. • The preliminary design of the isolated IRIS is the application of the procedure. -- Abstract: The research work here described is devoted to the development of a numerical procedure for the computation of seismic fragilities for equipment and structural components in Nuclear Power Plants; in particular, reference is made, in the present paper, to the case of isolated buildings. The proposed procedure for fragility computation makes use of the Response Surface Methodology to model the influence of the random variables on the dynamic response. To account for stochastic loading, the latter is computed by means of a simulation procedure. Given the Response Surface, the Monte Carlo method is used to compute the failure probability. The procedure is here applied to the preliminary design of the Nuclear Power Plant reactor building within the International Reactor Innovative and Secure international project; the building is equipped with a base isolation system based on the introduction of High Damping Rubber Bearing elements showing a markedly non linear mechanical behavior. The fragility analysis is performed assuming that the isolation devices become the critical elements in terms of seismic risk and that, once base-isolation is introduced, the dynamic behavior of the building can be captured by low-dimensional numerical models

Association of social isolation and health across different racial and ethnic groups of older Americans.

Science.gov (United States)

Miyawaki, Christina E

2015-11-01

Social isolation is a social and public health problem that affects people of all ages, especially elders. Previous studies have found that social isolation across numerous industrialised countries is associated with negative health outcomes. However, it is unknown whether and how this association differs by race/ethnicity and age. To begin to address this gap, this study examines the association of social isolation and physical and mental health among Black, White and Hispanic elders in the United States of America. Building on Cornwell and Waite's perceived isolation and social disconnectedness dimension model of social isolation, the author used multi-stage survey data from a nationally representative sample of 3,005 community-residing adults aged 57-85 from the National Social Life, Health, and Aging Project. Tests for association were conducted on health by age, gender, marital status, education and race/ethnicity separately. Multivariate logistic regressions were used to test the association of social isolation and health exclusively and separately among these three groups. Results showed that social isolation is strongly associated with physical and mental health. Both perceived isolation and social disconnectedness had a significant negative association with physical and mental health among White elders. For Blacks, social disconnectedness is negatively associated with their physical health while perceived isolation had a negative association with mental health. Among Hispanic elders, there seemed to be no association between social isolation and physical health, but a significant negative association was found with their mental health. Despite various associated patterns, however, social isolation overall was associated with health outcomes that were similar across three elder groups. By identifying factors influencing social isolation and health among minority older Americans, this study has relevance to the development of culturally sensitive health

Phylogenetic and physiological diversity of microorganisms isolated from a deep greenland glacier ice core

Science.gov (United States)

Miteva, V. I.; Sheridan, P. P.; Brenchley, J. E.

2004-01-01

We studied a sample from the GISP 2 (Greenland Ice Sheet Project) ice core to determine the diversity and survival of microorganisms trapped in the ice at least 120,000 years ago. Previously, we examined the phylogenetic relationships among 16S ribosomal DNA (rDNA) sequences in a clone library obtained by PCR amplification from genomic DNA extracted from anaerobic enrichments. Here we report the isolation of nearly 800 aerobic organisms that were grouped by morphology and amplified rDNA restriction analysis patterns to select isolates for further study. The phylogenetic analyses of 56 representative rDNA sequences showed that the isolates belonged to four major phylogenetic groups: the high-G+C gram-positives, low-G+C gram-positives, Proteobacteria, and the Cytophaga-Flavobacterium-Bacteroides group. The most abundant and diverse isolates were within the high-G+C gram-positive cluster that had not been represented in the clone library. The Jukes-Cantor evolutionary distance matrix results suggested that at least 7 isolates represent new species within characterized genera and that 49 are different strains of known species. The isolates were further categorized based on the isolation conditions, temperature range for growth, enzyme activity, antibiotic resistance, presence of plasmids, and strain-specific genomic variations. A significant observation with implications for the development of novel and more effective cultivation methods was that preliminary incubation in anaerobic and aerobic liquid prior to plating on agar media greatly increased the recovery of CFU from the ice core sample.

Radioactive waste isolation in salt: peer review of the Office of Nuclear Waste Isolation's report on the Organic Geochemistry of Deep Groundwaters from the Palo Duro Basin, Texas

International Nuclear Information System (INIS)

Fenster, D.F.; Brookins, D.G.; Harrison, W.; Seitz, M.G.; Lerman, A.; Stamoudis, V.C.

1984-08-01

This report summarizes Argonne's review of the Office of Nuclear Waste Isolation's (ONWI's) final report entitled The Organic Geochemistry of Deep Ground Waters from the Palo Duro Basin, Texas, dated September 1983. Recommendations are made for improving the ONWI report. The main recommendation is to make the text consistent with the title and with the objective of the project as stated in the introduction. Three alternatives are suggested to accomplish this

Dynamic isolation technologies in negative pressure isolation wards

CERN Document Server

Xu, Zhonglin

2017-01-01

This book presents novel design principles and technologies for dynamic isolation based on experimental studies. These approaches have now become the local standard in Beijing and are currently being promoted for use nationwide. Further, the book provides details of measures and guidelines for the design process. Departing from the traditional understanding that isolation wards should be designed with high negative pressure, airtight doors and fresh air, it establishes the basis for designing biological clean rooms, including isolation wards, using a simple and convenient scientific approach. This book is intended for designers, engineers, researchers, hospital management staff and graduate students in heating ventilation air conditioning (HVAC), air cleaning technologies and related areas.

Isolated Proofs of Knowledge and Isolated Zero Knowledge

DEFF Research Database (Denmark)

Damgård, Ivan Bjerre; Nielsen, Jesper Buus; Wichs, Daniel

2008-01-01

. This is because the prover may just be forwarding messages between the environment and the verifier while the environment performs all the necessary computation. In this paper we consider an ℓ-isolated prover, which is restricted to exchanging at most ℓ bits of information with its environment. We introduce a new...... notion called ℓ-isolated proofs of knowledge (ℓ-IPoK). These protocols securely ensure that an ℓ-isolated prover knows the witness. To prevent the above-mentioned attack, an ℓ-IPoK protocol has to have communication complexity greater than ℓ. We show that for any relation in NP and any value ℓ...

Clonal distribution of pneumococcal serotype 19F isolates from Ghana

DEFF Research Database (Denmark)

Sparding, Nadja; Dayie, Nicholas Tete Kwaku Dzifa; Mills, Richael O.

2015-01-01

Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide. Pneumococcal strains are classified according to their capsular polysaccharide and more than 90 different serotypes are currently known. In this project, three distinct groups of pneumococcal carriage isolates from Gh...... in Ghana in that many new clones were identified. This supports the importance of continued monitoring of pneumococcal carriage in Ghana and elsewhere when vaccines, e.g., PCV-13, have been introduced to monitor the possible future spread of antimicrobial resistant clones....

Sporulation of four arbuscular mycorrhizal fungi isolates inside dead seed cavities and glass capillaries

Czech Academy of Sciences Publication Activity Database

Rydlová, Jana; Batkhuugyin, Enkhtuya; Vosátka, Miroslav

2004-01-01

Roč. 36, - (2004), s. 269-284 ISSN 0334-5114 R&D Projects: GA AV ČR KSK6005114; GA ČR GA526/99/P032; GA MŠk OC 838.10 Institutional research plan: CEZ:AV0Z6005908 Keywords : Chenopodium album seeds * Glomus * indigenous AMF isolates Subject RIV: EF - Botanics Impact factor: 0.682, year: 2004

Myoglobin structure and function: A multiweek biochemistry laboratory project.

Science.gov (United States)

Silverstein, Todd P; Kirk, Sarah R; Meyer, Scott C; Holman, Karen L McFarlane

2015-01-01

We have developed a multiweek laboratory project in which students isolate myoglobin and characterize its structure, function, and redox state. The important laboratory techniques covered in this project include size-exclusion chromatography, electrophoresis, spectrophotometric titration, and FTIR spectroscopy. Regarding protein structure, students work with computer modeling and visualization of myoglobin and its homologues, after which they spectroscopically characterize its thermal denaturation. Students also study protein function (ligand binding equilibrium) and are instructed on topics in data analysis (calibration curves, nonlinear vs. linear regression). This upper division biochemistry laboratory project is a challenging and rewarding one that not only exposes students to a wide variety of important biochemical laboratory techniques but also ties those techniques together to work with a single readily available and easily characterized protein, myoglobin. © 2015 International Union of Biochemistry and Molecular Biology.

Effect of isolation techniques on the characteristics of pigeon pea (Cajanus cajan) protein isolates.

Science.gov (United States)

Adenekan, Monilola K; Fadimu, Gbemisola J; Odunmbaku, Lukumon A; Oke, Emmanuel K

2018-01-01

In this study, the effect of different isolation techniques on the isolated proteins from pigeon pea was investigated. Water, methanol, ammonium sulfate, and acetone were used for the precipitation of proteins from pigeon pea. Proximate composition, and antinutritional and functional properties of the pigeon pea flour and the isolated proteins were measured. Data generated were statistically analyzed. The proximate composition of the water-extracted protein isolate was moisture 8.30%, protein 91.83%, fat 0.25%, ash 0.05%, and crude fiber 0.05%. The methanol-extracted protein isolate composition was moisture 7.87%, protein 91.83%, fat 0.17%, and ash 0.13%, while crude fiber and carbohydrates were not detected. The composition of the ammonium sulfate-extracted protein isolate was moisture 7.73%, protein 91.73%, fat 0.36, ash 0.13%, and crude fiber 0.67%. The acetone-extracted protein isolate composition was moisture 8.03%, protein 91.50%, ash 0.67%, and fat 0.30%, but crude fiber and carbohydrates were not detected. The isolate precipitated with ammonium sulfate displayed the highest foaming capacity (37.63%) and foaming stability (55.75%). Isolates precipitated with methanol and acetone had the highest water absorption capacity (160%). Pigeon pea protein isolates extracted with methanol and ammonium sulfate had the highest oil absorption capacity of 145%. Protein isolates recovered through acetone and methanol had the highest emulsifying capacity of 2.23% and emulsifying stability of 91.47%, respectively. The proximate composition of the recovered protein isolates were of high purity. This shows the efficiency of the extraction techniques. The isolates had desirable solubility index. All the isolation techniques brought significant impact on the characteristics of the isolated pigeon pea protein.

Characterization of Two Microbial Isolates from Andean Lakes in Bolivia

Science.gov (United States)

Demergasso, C.; Blamey, J.; Escudero, L.; Chong, G.; Casamayor, E. O.; Cabrol, N. A.; Grin, E. A.; Hock, A.; Kiss, A.; Borics, G.

2004-01-01

We are currently investigating the biological population present in the highest and least explored perennial lakes on earth in the Bolivian and Chilean Andes, including several volcanic crater lakes of more than 6000 m elevation, in combination of microbiological and molecular biological methods. Our samples were collected in saline lakes of the Laguna Blanca Laguna Verde area in the Bolivian Altiplano and in the Licancabur volcano crater (27 deg. 47 min S/67 deg. 47 min. W) in the ongoing project studying high altitude lakes. The main goal of the project is to look for analogies with Martian paleolakes. These Bolivian lakes can be described as Andean lakes following the classification of Chong. We have attempted to isolate pure cultures and phylogenetically characterize prokaryotes that grew under laboratory conditions. Sediment samples taken from the Licancabur crater lake (LC), Laguna Verde (LV), and Laguna Blanca (LB) were analyzed and cultured using enriched liquid media under both aerobic and anaerobic conditions. All cultures were incubated at room temperature (15 to 20 C) and under light exposure. For the reported isolates, 36 hours incubation were necessary for reaching optimal optical densities to consider them viable cultures. Ten serial dilutions starting from 1% inoculum were required to obtain a suitable enriched cell culture to transfer into solid media. Cultures on solid medium were necessary to verify the formation of colonies in order to isolate pure cultures. Different solid media were prepared using several combinations of both trace minerals and carbohydrates sources in order to fit their nutrient requirements. The microorganisms formed individual colonies on solid media enriched with tryptone, yeast extract and sodium chloride. Cells morphology was studied by optical and electronic microscopy. Rodshape morphologies were observed in most cases. Total bacterial genomic DNA was isolated from 50 ml late-exponential phase culture by using the CTAB

Development of Seismic Isolation Systems Using Periodic Materials

Energy Technology Data Exchange (ETDEWEB)

Yan, Yiqun [Univ. of Houston, Houston, TX (United States); Mo, Yi-Lung [Univ. of Houston, Houston, TX (United States); Menq, Farn-Yuh [Univ. of Texas, Austin, TX (United States); Stokoe, II, Kenneth H. [Univ. of Texas, Austin, TX (United States); Perkins, Judy [Prairie View A & M University, Prairie View, TX (United States); Tang, Yu [Argonne National Lab. (ANL), Argonne, IL (United States)

2014-12-10

Advanced fast nuclear power plants and small modular fast reactors are composed of thin-walled structures such as pipes; as a result, they do not have sufficient inherent strength to resist seismic loads. Seismic isolation, therefore, is an effective solution for mitigating earthquake hazards for these types of structures. Base isolation, on which numerous studies have been conducted, is a well-defined structure protection system against earthquakes. In conventional isolators, such as high-damping rubber bearings, lead-rubber bearings, and friction pendulum bearings, large relative displacements occur between upper structures and foundations. Only isolation in a horizontal direction is provided; these features are not desirable for the piping systems. The concept of periodic materials, based on the theory of solid-state physics, can be applied to earthquake engineering. The periodic material is a material that possesses distinct characteristics that prevent waves with certain frequencies from being transmitted through it; therefore, this material can be used in structural foundations to block unwanted seismic waves with certain frequencies. The frequency band of periodic material that can filter out waves is called the band gap, and the structural foundation made of periodic material is referred to as the periodic foundation. The design of a nuclear power plant, therefore, can be unified around the desirable feature of a periodic foundation, while the continuous maintenance of the structure is not needed. In this research project, three different types of periodic foundations were studied: one-dimensional, two-dimensional, and three-dimensional. The basic theories of periodic foundations are introduced first to find the band gaps; then the finite element methods are used, to perform parametric analysis, and obtain attenuation zones; finally, experimental programs are conducted, and the test data are analyzed to verify the theory. This procedure shows that the

Validation of a for anaerobic bacteria optimized MALDI-TOF MS biotyper database: The ENRIA project.

Science.gov (United States)

Veloo, A C M; Jean-Pierre, H; Justesen, U S; Morris, T; Urban, E; Wybo, I; Kostrzewa, M; Friedrich, A W

2018-03-12

Within the ENRIA project, several 'expertise laboratories' collaborated in order to optimize the identification of clinical anaerobic isolates by using a widely available platform, the Biotyper Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS). Main Spectral Profiles (MSPs) of well characterized anaerobic strains were added to one of the latest updates of the Biotyper database db6903; (V6 database) for common use. MSPs of anaerobic strains nominated for addition to the Biotyper database are included in this validation. In this study, we validated the optimized database (db5989 [V5 database] + ENRIA MSPs) using 6309 anaerobic isolates. Using the V5 database 71.1% of the isolates could be identified with high confidence, 16.9% with low confidence and 12.0% could not be identified. Including the MSPs added to the V6 database and all MSPs created within the ENRIA project, the amount of strains identified with high confidence increased to 74.8% and 79.2%, respectively. Strains that could not be identified using MALDI-TOF MS decreased to 10.4% and 7.3%, respectively. The observed increase in high confidence identifications differed per genus. For Bilophila wadsworthia, Prevotella spp., gram-positive anaerobic cocci and other less commonly encountered species more strains were identified with higher confidence. A subset of the non-identified strains (42.1%) were identified using 16S rDNA gene sequencing. The obtained identities demonstrated that strains could not be identified either due to the generation of spectra of insufficient quality or due to the fact that no MSP of the encountered species was present in the database. Undoubtedly, the ENRIA project has successfully increased the number of anaerobic isolates that can be identified with high confidence. We therefore recommend further expansion of the database to include less frequently isolated species as this would also allow us to gain valuable insight into the clinical

Wire rope isolators for vibration isolation of equipment and structures – A review

International Nuclear Information System (INIS)

Balaji, P S; Rahman, M E; Lau, H H; Moussa, Leblouba

2015-01-01

Vibrations and shocks are studied using various techniques and analyzed to predict their detrimental effect on the equipment and structures. In cases, where the effects of vibration become unacceptable, it may cause structural damage and affect the operation of the equipment. Hence, adding a discrete system to isolate the vibration from source becomes necessary. The Wire Rope Isolator (WRI) can be used to effectively isolate the system from disturbing vibrations. The WRI is a type of passive isolator that exhibits nonlinear behavior. It consists of stranded wire rope held between two metal retainer bars and the metal wire rope is made up of individual wire strands that are in frictional contact with each other, hence, it is a kind of friction-type isolator. This paper compiles the research work on wire rope isolators. This paper presents the research work under two categories, namely monotonic and cyclic loading behaviors of WRI. The review also discusses the different terminologies associated with vibration isolation system and highlights the comparison between various isolation systems. (paper)

Automated methods for single-stranded DNA isolation and dideoxynucleotide DNA sequencing reactions on a robotic workstation

International Nuclear Information System (INIS)

Mardis, E.R.; Roe, B.A.

1989-01-01

Automated procedures have been developed for both the simultaneous isolation of 96 single-stranded M13 chimeric template DNAs in less than two hours, and for simultaneously pipetting 24 dideoxynucleotide sequencing reactions on a commercially available laboratory workstation. The DNA sequencing results obtained by either radiolabeled or fluorescent methods are consistent with the premise that automation of these portions of DNA sequencing projects will improve the reproducibility of the DNA isolation and the procedures for these normally labor-intensive steps provides an approach for rapid acquisition of large amounts of high quality, reproducible DNA sequence data

Mutation and premating isolation

Science.gov (United States)

Woodruff, R. C.; Thompson, J. N. Jr

2002-01-01

While premating isolation might be traceable to different genetic mechanisms in different species, evidence supports the idea that as few as one or two genes may often be sufficient to initiate isolation. Thus, new mutation can theoretically play a key role in the process. But it has long been thought that a new isolation mutation would fail, because there would be no other individuals for the isolation-mutation-carrier to mate with. We now realize that premeiotic mutations are very common and will yield a cluster of progeny carrying the same new mutant allele. In this paper, we discuss the evidence for genetically simple premating isolation barriers and the role that clusters of an isolation mutation may play in initiating allopatric, and even sympatric, species divisions.

The introduction of wind powered pumped storage Systems in Greek isolated systems. Experiences and perspectives

International Nuclear Information System (INIS)

Katsaprakakis, Dimitris Al.; Christakis, Dimitris G.

2009-01-01

Full text: In the present paper, the experiences gained from the study of Wind Powered Pumped Storage Systems (WP-PSS), introduced in Greek isolated power production systems, are presented. The presented systems were studied in the frames of either research or development projects, financed by the public or private sector. Two main categories of WP-PSS are presented: The introduction of WP-PSS for power peak saving. The construction and the operation framework of these systems are fully defined in the relevant Greek laws. These systems were studied in the frames of individual development projects. The introduction of WPPSS aiming at the maximisation of wind power. These systems are not yet fully defined in the Greek legislation and were studied in the frames of research works. More than ten WP-PSS have been technically and economically studied so far. Each one of them has been introduced in a Greek isolated insular power system, integrated according to the to the specific design parameters of the examined insular system (power demand, wind potential, land morphology, etc). All the accomplished studies may be considered as parts of one long-time unified project, aiming at the investigation of the prerequisites for the maximisation of the Renewable Energy Sources (R.E.S.) exploitation in Greece. The general conclusions arisen from the so far accomplished work are: The R.E.S. penetration percentage in the Greek insular systems may exceed 80% of the annual energy demand, by introducing pumped storage systems as storage device. The electricity production cost is minimized, even in the isolated systems of small size. The corresponding investments exhibit very good economical indexes, regardless the possible availability of initial capitals subsidy. In case of initial capitals subsidy availability, the investments exhibit quite attractive economical indexes. The dynamic security of the proposed systems (author)

Application of seismic isolation for seismic strengthening of buildings damaged by the earthquake of L’Aquila

International Nuclear Information System (INIS)

Corsetti, Daniele

2015-01-01

The earthquake of 6 April 2009 destroyed the social and economic network fabric of the town of 'L'Aquila'. Since then, many buildings have been restored and some designers have taken the opportunity of rebuilding the town applying innovative technologies. In this context, despite the inevitable bureaucratic hurdles and economic constraints, added to the death of Mr. Mancinelli in 2012 (GLIS Member), several projects were carried out on existing buildings with the idea of applying base seismic isolation. A decade after the first application of this solution on an existing building in Fabriano by Mr. Mancinelli, the experience has proved to be a success, both in terms of achieved results and ease of management. For L’Aquila earthquake the idea was to replicate the positive experience of the “Marche earthquake”, though the problems and obstacles to face often were substantially different. The experience outlined below is a summary of the issues faced and resolved in two projects, taking into account that any solution can be further improved and refined depending on the ability and sensitivity of the designer. We have come to the conclusion that the projects of a base seismic isolation of existing buildings are 'tailor-made' projects, and that the solutions have to be analysed a case by case, even if the main concepts are simple and applicable to a wide range of buildings [it

Reproductive isolating barriers between colour-differentiated populations of an African annual killifish, Nothobranchius korthausae (Cyprinodontiformes)

Czech Academy of Sciences Publication Activity Database

Reichard, Martin; Polačik, Matej

2010-01-01

Roč. 100, č. 1 (2010), s. 62-72 ISSN 0024-4066 R&D Projects: GA ČR GP206/06/P152 Institutional research plan: CEZ:AV0Z60930519 Keywords : allopatric divergence * assortative mating * colour polymorphism * mating experience * premating barriers * reproductive isolation Subject RIV: EG - Zoology Impact factor: 2.166, year: 2010

Hydrologic studies for the Waste Isolation Pilot Plant

International Nuclear Information System (INIS)

Davies, P.B.

1994-01-01

The objective of this paper is to provide a general overview of hydrologic conditions at the Waste Isolation Pilot Plant (WIPP) by describing several key hydrologic studies that have been carried out as part of the site characterization program over the last 20 years. The paper is composed of three parts: background information about general objectives of the WIPP project; information about the geologic and hydrologic setting of the facility; and information about three aspects of the hydrologic system that are important to understanding the long-term performance of the WIPP facility. For additional detailed information, the reader is referred to the references cited in the text

Agricultural production - Phase 2. Indonesia. Isolation of arboviruses, their identification and the identification of their culicoides vectors in Indonesia

International Nuclear Information System (INIS)

Mellor, P.S.

1991-01-01

The aims of the two-week mission were to provide assistance in studies to determine the incidence and importance of arbovirus infection in ruminants in Indonesia, specifically to help with identification of the vectors tat transmit bluetongue and related arbovirus infections, and to develop work plans for future studies under the project. The report contains detailed information on handling systems for Culicoides species, on identification of Culicoides to be used for viral isolation and on the isolation of virus from Culicoides

Reference stratigraphy and rock properties for the Waste Isolation Pilot Plant (WIPP) project

International Nuclear Information System (INIS)

Krieg, R.D.

1984-01-01

A stratigraphic description of the country rock near the working horizon at the Waste Isolation Pilot Plant (WIPP) is presented along with a set of mechanical and thermal properties of materials involved. Data from 41 cores and shafts are examined. The entire stratigraphic section is found to vary in elevation in a regular manner, but individual layer thicknesses and relative separation between layers are found to have no statistically significant variation over the one mile north to south extent of the working horizon. The stratigraphic description is taken to be relative to the local elevation of Anhydrite b. The material properties have been updated slightly from those in the July 1981 Reference Stratigraphy. This reference stratigraphy/properties document is intended primarily for use in thermal/structural analyses. This document supercedes the July 1981 stratigraphy/properties document. 31 references, 7 figures

A new approach to the isolation and characterization of wheat flour allergens

Czech Academy of Sciences Publication Activity Database

Šotkovský, Petr; Sklenář, Jan; Halada, Petr; Cinová, Jana; Šetinová, I.; Kainarová, Andrea; Goliáš, Jaroslav; Pavlásková, Kateřina; Honzová, S.; Tučková, Ludmila

2011-01-01

Roč. 41, č. 7 (2011), s. 1031-1043 ISSN 0954-7894 R&D Projects: GA ČR GA310/07/0414; GA ČR GD310/08/H077; GA AV ČR IAA500200801; GA MŠk 2B06155; GA MŠk LC07017 Institutional research plan: CEZ:AV0Z50200510 Keywords : basophil activation * IgE antibodies * isolation Subject RIV: EC - Immunology Impact factor: 5.032, year: 2011

Flexibility and Project Value: Interactions and Multiple Real Options

Science.gov (United States)

Čulík, Miroslav

2010-06-01

This paper is focused on a project valuation with embedded portfolio of real options including their interactions. Valuation is based on the criterion of Net Present Value on the simulation basis. Portfolio includes selected types of European-type real options: option to expand, contract, abandon and temporarily shut down and restart a project. Due to the fact, that in reality most of the managerial flexibility takes the form of portfolio of real options, selected types of options are valued not only individually, but also in combination. The paper is structured as follows: first, diffusion models for forecasting of output prices and variable costs are derived. Second, project value is estimated on the assumption, that no real options are present. Next, project value is calculated with the presence of selected European-type options; these options and their impact on project value are valued first in isolation and consequently in different combinations. Moreover, intrinsic value evolution of given real options with respect to the time of exercising is analysed. In the end, results are presented graphically; selected statistics and risk measures (Value at Risk, Expected Shortfall) of the NPV's distributions are calculated and commented.

Management of citation verification requests for multiple projects at Sandia National Laboratories

International Nuclear Information System (INIS)

Crawford, C.S.

1995-01-01

Sandia National Laboratories' (SNL) Technical Library is now responsible for providing citation verification management support for all references cited in technical reports issued by the Nuclear Waste Management (NWM) Program. This paper dancing how this process is managed for the Yucca Mountain Site Characterization (YWP), Waste Isolation Pilot Plant (WIPP), Idaho National Engineering Laboratory (INEL), and Greater Confinement Disposal (GCD) projects. Since technical reports are the main product of these projects, emphasis is placed on meeting the constantly evolving needs of these customers in a timely and cost-effective manner

Barriers to clean development mechanism renewable energy projects in Mexico

International Nuclear Information System (INIS)

Lokey, Elizabeth

2009-01-01

Mexico is not reaching its full potential to capture benefits from clean development mechanism (CDM) projects because of its limited market for independent power producers (IPPs) and the barriers imposed on these entities by the state-run electric utility that controls most of the country's generation and transmission. This state-run entity has pursued CDM revenues only in isolated cases where international financial assistance was given because it is bound by law to pursue the least-cost generation option for its customers. Recent changes in Mexican legislation that provide incentives for renewable energy development could open the marketplace for these types of projects. (author)

The Use of Volunteers in Local Study Library Projects: A Case Study of the Walter Gardiner Photography Project

Directory of Open Access Journals (Sweden)

Beth Hewitt

2012-03-01

Full Text Available Objectives – Interviews with library staff and volunteers were conducted to evaluate the use of volunteers in UK public libraries via a case study of the Walter Gardiner Photographic Project, a digitisation project based in Worthing Library, to inform future guidelines on volunteer usage and to make recommendations to existing practice.Methods – Fourteen semi-structured interviews were carried out to explore the perceptions and experiences of both staff and volunteers of the project. All interviews were fully transcribed and then coded to identify emergent themes.Results – Key positives for volunteers were professional training, good time management and organization by staff, the friendliness and approachability of staff, and the informal nature of the volunteering. Enjoyment of the work and forming close relationships with others were key motivating factors. For staff, the completion of work which would have otherwise been impossible was the most positive outcome. Problem areas identified by volunteers were lack of contact time with project staff and feeling isolated from other library staff. For project staff, a lack of professionalism on behalf of some volunteers was the primary negative. Key issues to emerge were the need to strike a balance between formal and informal management, the need for good integration between the volunteers and host organization, and the importance of acknowledging the nature of the voluntary commitment.Conclusions – The project proved overall to be a successful example of using volunteers in public library projects with good examples of volunteer recruitment, training, and management being demonstrated. Areas of conflict that did arise stemmed from differing expectations of levels of service between staff and volunteers. Clarification on these expectations through a written volunteer agreement is advocated for further projects.

Life cycle costs for disposal and assured isolation of low-level radioactive waste in Connecticut

International Nuclear Information System (INIS)

Chau, B.; Sutherland, A.A.; Baird, R.D.

1998-03-01

This document presents life cycle costs for a low-level radioactive disposal facility and a comparable assured isolation facility. Cost projections were based on general plans and assumptions, including volume projections and operating life, provided by the Connecticut Hazardous Waste Management Service, for a facility designed to meet the State's needs. Life cycle costs include the costs of pre-construction activities, construction, operations, closure, and post-closure institutional control. In order to provide a better basis for understanding the relative magnitude of near-term costs and future costs, the results of present value analysis of ut-year costs are provided

Draft forecast of the final report for the comparison to 40 CFR Part 191, Subpart B, for the Waste Isolation Pilot Plant

Energy Technology Data Exchange (ETDEWEB)

Bertram-Howery, S.G.; Marietta, M.G.; Anderson, D.R.; Gomez, L.S.; Rechard, R.P. (Sandia National Labs., Albuquerque, NM (USA)); Brinster, K.F.; Guzowski, R.V. (Science Applications International Corp., Albuquerque, NM (USA))

1989-12-01

The United States Department of Energy is planning to dispose of transuranic wastes, which have been generated by defense programs, at the Waste Isolation Pilot Plant. The WIPP Project will assess compliance with the requirements of the United States Environmental Protection Agency. This report forecasts the planned 1992 document, Comparison to 40 CFR, Part 191, Subpart B, for the Waste Isolation Pilot Plant (WIPP). 130 refs., 36 figs., 11 tabs.

THE ACS LCID PROJECT. I. SHORT-PERIOD VARIABLES IN THE ISOLATED DWARF SPHEROIDAL GALAXIES CETUS AND TUCANA

NARCIS (Netherlands)

Bernard, Edouard J.; Monelli, Matteo; Gallart, Carme; Drozdovsky, Igor; Stetson, Peter B.; Aparicio, Antonio; Cassisi, Santi; Mayer, Lucio; Cole, Andrew A.; Hidalgo, Sebastian L.; Skillman, Evan D.; Tolstoy, Eline

2009-01-01

We present the first study of the variable star populations in the isolated dwarf spheroidal galaxies (dSphs) Cetus and Tucana. Based on Hubble Space Telescope images obtained with the Advanced Camera for Surveys in the F475W and F814W bands, we identified 180 and 371 variables in Cetus and Tucana,

Isolation and cultivation of planktonic freshwater microbes is essential for a comprehensive understanding of their ecology.

Czech Academy of Sciences Publication Activity Database

Salcher, Michaela M.; Šimek, Karel

2016-01-01

Roč. 77, č. 3 (2016), s. 183-196 ISSN 0948-3055 R&D Projects: GA ČR(CZ) GA13-00243S Institutional support: RVO:60077344 Keywords : autecology * axenic cultures * dilution to extinction * ecophysiology * genomics * isolation of freshwater microbes * targeted enrichment Subject RIV: EE - Microbiology, Virology Impact factor: 1.633, year: 2016

SYMBIODINIUM ISOLATES FROM STONY CORAL: ISOLATION, GROWTH CHARACTERISTICS AND EFFECTS OF UV IRRADIATION

Science.gov (United States)

Symbiodinium spp. Isolates from Stony Coral: Isolation, Growth Characteristics and Effects of UV Irradiation (Abstract). J. Phycol. 37(3):42-43.Symbiodinium species were isolated from Montipora capitata, Acropora palmata and two field samples of Porites porites. Cultures ...

QA lessons learned for parameter control from the WIPP Project

International Nuclear Information System (INIS)

Richards, R.R.

1998-01-01

This paper provides a summary of lessons learned from experiences on the Waste Isolation Pilot Plant (WJPP) Project in implementation of quality assurance controls surrounding inputs for performance assessment analysis. Since the performance assessment (PA) process is inherent in compliance determination for any waste repository, these lessons-learned are intended to be useful to investigators, analysts, and Quality Assurance (QA) practitioners working on high level waste disposal projects. On the WIPP Project, PA analyses for regulatory-compliance determination utilized several inter-related computer programs (codes) that mathematically modeled phenomena such as radionuclide release, retardation, and transport. The input information for those codes are the parameters that are the subject of this paper. Parameters were maintained in a computer database, which was then queried electronically by the PA codes whenever input was needed as the analyses were run

Salt repository project: Technical progress report for the quarter 1 April--30 June 1987

International Nuclear Information System (INIS)

1987-01-01

This document reports the progress being made each quarter on the development of a geologic repository in salt for the permanent disposal of high-level nuclear waste. The reporting elements are arranged by the work breakdown structure so that related studies are presented together. The studies are reported by the Office of Nuclear Waste Isolation, a prime contractor of the US Department of Energy (DOE) Salt Repository Project Office. The studies include work by other DOE prime contractors and by contractors to the Office of Nuclear Waste Isolation

Salt Repository Project technical progress report for the quarter 1 January--31 March 1987

International Nuclear Information System (INIS)

1988-03-01

This document reports the progress being made each quarter on the development of a geologic repository in salt for the permanent disposal of high-level nuclear waste. The reporting elements are arranged by the work breakdown structure so that related studies are presented together. The studies are reported by the Office of Nuclear Waste Isolation, a prime contractor of the US Department of energy (DOE) Salt Repository Project Office. The studies include work by other DOE prime contractors and by contractors to the Office of Nuclear Waste Isolation. 23 refs., 1 fig

Radioactive waste isolation in salt: Peer review of the Office of Nuclear Waste Isolation's draft report on an issues hierarchy and data needs for site characterization

International Nuclear Information System (INIS)

Harrison, W.; Fenster, D.F.; Ditmars, J.D.; Paddock, R.A.; Rote, D.M.; Hambley, D.F.; Seitz, M.G.; Hull, A.B.

1986-12-01

At the request of the Salt Repository Project (SRPO), Argonne National Laboratory conducted an independent peer review of a report by the Battelle Office of Nuclear Waste Isolation entitled ''Salt Repository Project Issues Hierarchy and Data Needs for Site Characterization (Draft).'' This report provided a logical structure for evaluating the outstanding questions (issues) related to selection and licensing of a site as a high-level waste repository. It also provided a first estimate of the information and data necessary to answer or resolve those questions. As such, this report is the first step in developing a strategy for site characterization. Microfiche copies of ''Draft Issues Hierarchy, Resolution Strategy, and Information Needs for Site Characterization and Environmental/Socioeconomic Evaluation - July, 1986'' and ''Issues Hierarchy and Data Needs for Site Characterization - February, 1985'' are included in the back pocket of this report

SDN Project

Energy Technology Data Exchange (ETDEWEB)

Smith, Rhett [Schweitzer Engineering Laboratories Inc, Pullman, WA (United States)

2016-12-23

The SDN Project completed on time and on budget and successfully accomplished 100% of the scope of work outlined in the original Statement of Project Objective (SOPO). The SDN Project formed an alliance between Ameren Corporation, University of Illinois Urbana- Champaign (UIUC), Pacific Northwest National Laboratories (PNNL), and Schweitzer Engineering Laboratories, Inc. (SEL). The objective of the SDN Project is to address Topic Area of Interest 2: Sustain critical energy delivery functions while responding to a cyber-intrusion under Funding Opportunity Announcement DE-FOA-0000797. The goal of the project is to design and commercially release technology that provides a method to sustain critical energy delivery functions during a cyber intrusion and to do this control system operators need the ability to quickly identify and isolate the affected network areas, and re-route critical information and control flows around. The objective of the SDN Project is to develop a Flow Controller that monitors, configures, and maintains the safe, reliable network traffic flows of all the local area networks (LANs) on a control system in the Energy sector. The SDN team identified the core attributes of a control system and produced an SDN flow controller that has the same core attributes enabling networks to be designed, configured and deployed that maximize the whitelisted, deny-bydefault and purpose built networks. This project researched, developed and commercially released technology that: Enables all field networks be to configured and monitored as if they are a single asset to be protected; Enables greatly improved and even precalculated response actions to reliability and cyber events; Supports pre-configured localized response actions tailored to provide resilience against failures and centralized response to cyber-attacks that improve network reliability and availability; Architecturally enables the right subject matter experts, who are usually the information

A Multifunctional Isolated and Non-Isolated Dual Mode Converter for Renewable Energy Conversion Applications

Directory of Open Access Journals (Sweden)

Yiwang Wang

2017-11-01

Full Text Available In this paper, a multifunctional isolated and non-isolated dual-mode low-power converter was designed for renewable energy conversion applications such as photovoltaic power generation to achieve different operating modes under bi-directional electrical conversion. The proposed topology consists of a bidirectional non-isolated DC/DC circuit and an isolated converter with a high-frequency transformer, which merge the advantages of both the conventional isolated converter and non-isolated converter with the combination of the two converter technologies. Compared with traditional converters, the multifunctional converter can not only realize conventional bi-directional functions, but can also be applied for many different operation modes and meet the high output/input ratio demands with the two converter circuits operating together. A novel control algorithm was proposed to achieve the various functions of the proposed converter. An experimental platform based on the proposed circuit was established. Both the simulation and experimental results indicated that the proposed converter could provide isolated and non-isolated modes in different applications, which could meet different practical engineering requirements.

Methodology for Monitoring Sustainable Development of Isolated Microgrids in Rural Communities

Directory of Open Access Journals (Sweden)

Claudia Rahmann

2016-11-01

Full Text Available Microgrids are a rapidly evolving and increasingly common form of local power generation used to serve the needs of both rural and urban communities. In this paper, we present a methodology to evaluate the evolution of the sustainability of stand-alone microgrids projects. The proposed methodology considers a composite sustainability index (CSI that includes both positive and negative impacts of the operation of the microgrid in a given community. The CSI is constructed along environmental, social, economic and technical dimensions of the microgrid. The sub-indexes of each dimension are aggregated into the CSI via a set of adaptive weighting factors, which indicate the relative importance of the corresponding dimension in the sustainability goals. The proposed methodology aims to be a support instrument for policy makers especially when defining sound corrective measures to guarantee the sustainability of small, isolated microgrid projects. To validate the performance of the proposed methodology, a microgrid installed in the northern part of Chile (Huatacondo has been used as a benchmarking project.

Physics in isolation

International Nuclear Information System (INIS)

Anon.

1986-01-01

In late May, about 330 physicists made their way up to isolated and beautiful Lake Louise high in the Canadian Rockies about 100 miles west of Calgary in a second effort to increase interactions between particle and nuclear physicists. The conference series aims to foster exciting and diverse physics by bringing the different physicists together somewhere which is so isolated that they must interact with each other. The formula worked very well and isolated Lake Louise was a huge success

Physics in isolation

Energy Technology Data Exchange (ETDEWEB)

Anon.

1986-09-15

In late May, about 330 physicists made their way up to isolated and beautiful Lake Louise high in the Canadian Rockies about 100 miles west of Calgary in a second effort to increase interactions between particle and nuclear physicists. The conference series aims to foster exciting and diverse physics by bringing the different physicists together somewhere which is so isolated that they must interact with each other. The formula worked very well and isolated Lake Louise was a huge success.

The effect of long-term isolation in the confined space on the ground dominance

Czech Academy of Sciences Publication Activity Database

Šikl, Radovan; Šimeček, Michal; Lukavský, Jiří

2011-01-01

Roč. 40, Suppl. (2011), s. 148-148 ISSN 0301-0066. [European Conference on Visual Perception /34./. 28.08.2011-01.09.2011, Toulouse] R&D Projects: GA ČR GA406/09/2003 Institutional research plan: CEZ:AV0Z70250504 Keywords : visual space perception * ground dominance * long-term isolation Subject RIV: AN - Psychology http://www.perceptionweb.com/abstract.cgi?id=v110655

Radiation environmental impact assessment of radioactive substances of an airport transit storage construction projects

International Nuclear Information System (INIS)

Zhang Baozeng; Xia Zitong; Zou Zhaozhuang

2014-01-01

Radioactive substances belong to dangerous goods transport aviation. Radioactive substances impoundments construction purpose is to ensure that the radioactive material during transport to transport and the public to achieve full or isolation, the effects of radiation on the human body, property and the environment caused by the control to an acceptable level. According to the relevant national standards and norms, for radiation protection evaluation of project construction of an airport radioactive impoundments, feasibility of the construction project radiation environment. (authors)

Color-Removal by Microorganisms Isolated from Human Hands

Directory of Open Access Journals (Sweden)

Tsukasa Ito

2013-08-01

reported recently (6. To date this author has frequently obtained colorant-degrading bacterial isolates from human hands as a result of work on a scientific education project. This tip does not require analytical measurements. Students can examine a number of bacterial isolates simultaneously. Therefore, it is appropriate for high school and introductory level college courses.

Impact of Sample Type and DNA Isolation Procedure on Genomic Inference of Microbiome Composition

DEFF Research Database (Denmark)

Knudsen, Berith Elkær; Bergmark, Lasse; Munk, Patrick

2016-01-01

that in standard protocols. Based on this insight, we designed an improved DNA isolation procedure optimized for microbiome genomics that can be used for the three examined specimen types and potentially also for other biological specimens. A standard operating procedure is available from https://dx.doi.org/10......Explorations of complex microbiomes using genomics greatly enhance our understanding about their diversity, biogeography, and function. The isolation of DNA from microbiome specimens is a key prerequisite for such examinations, but challenges remain in obtaining sufficient DNA quantities required...... for certain sequencing approaches, achieving accurate genomic inference of microbiome composition, and facilitating comparability of findings across specimen types and sequencing projects. These aspects are particularly relevant for the genomics-based global surveillance of infectious agents and antimicrobial...

Optimum Shock Isolation

National Research Council Canada - National Science Library

Bolotnik, Nikolai

2001-01-01

.... Several types of performance criteria for isolation are considered, the most important of which are the peak force transmitted to the body to be isolated and the maximum displacement of the body relative to the base...

Study for the energization of isolated community in the Amazon - Canaa Micro Hydropower Project; Estudo para a energizacao de comunidade isolada na Amazonia - Projeto Microcentral Canaa

Energy Technology Data Exchange (ETDEWEB)

Tiago Filho, Geraldo Lucio; Lemos, Helmo; Nogueira, Fabio Jose Horta [Universidade Federal de Itajuba (UNIFEI), MG (Brazil). Inst. de Recursos Naturais. Centro Nacional de Referencias em PCH' s], Emails: tiago@unifei.edu.br, helmo@unifei.edu.br, fabioh@unifei.edu.br

2006-07-01

The initiatives for electrification of remote communities have proven, so far, to difficult economic sustainability, with high rates of discontinuation of service and low quality of electricity provided. Another important aspect of these initiatives is great difficulty for the energy supply in these communities. The program 'Luz para Todos' (Light for All), launched by federal government in 2002, is an alternative that aims to universalize the service of electricity in all throughout the country, mainly of small isolated communities by giving them access to development due to the arrival of energy. One of these communities who will benefit from the program is the Community settlement of Nova Canaa, located in Pimenta Bueno in the State of Rondonia in the Amazon region. It will be met 55 families who never had access to a power quality and continuous supply. The relevance of this project is expressed by the possibility of replication of its management model for other communities in the country, contributing to the improvement of quality of life, poverty reduction and rural exodus. (author)

Isolated patellofemoral osteoarthritis.

NARCIS (Netherlands)

Jonbergen, J.P.W. van; Poolman, R.W.; Kampen, A. van

2010-01-01

BACKGROUND AND PURPOSE: The optimal treatment for isolated patellofemoral osteoarthritis is unclear at present. We systematically reviewed the highest level of available evidence on the nonoperative and operative treatment of isolated patellofemoral osteoarthritis to develop an evidenced-based

Modeling and Performance Considerations for Automated Fault Isolation in Complex Systems

Science.gov (United States)

Ferrell, Bob; Oostdyk, Rebecca

2010-01-01

The purpose of this paper is to document the modeling considerations and performance metrics that were examined in the development of a large-scale Fault Detection, Isolation and Recovery (FDIR) system. The FDIR system is envisioned to perform health management functions for both a launch vehicle and the ground systems that support the vehicle during checkout and launch countdown by using suite of complimentary software tools that alert operators to anomalies and failures in real-time. The FDIR team members developed a set of operational requirements for the models that would be used for fault isolation and worked closely with the vendor of the software tools selected for fault isolation to ensure that the software was able to meet the requirements. Once the requirements were established, example models of sufficient complexity were used to test the performance of the software. The results of the performance testing demonstrated the need for enhancements to the software in order to meet the demands of the full-scale ground and vehicle FDIR system. The paper highlights the importance of the development of operational requirements and preliminary performance testing as a strategy for identifying deficiencies in highly scalable systems and rectifying those deficiencies before they imperil the success of the project

Draft Genome Sequence of Exiguobacterium sp. Strain BMC-KP, an Environmental Isolate from Bryn Mawr, Pennsylvania.

Science.gov (United States)

Hyson, Peter; Shapiro, Joshua A; Wien, Michelle W

2015-10-08

Exiguobacterium sp. strain BMC-KP was isolated as part of a student environmental sampling project at Bryn Mawr College, PA. Sequencing of bacterial DNA assembled a 3.32-Mb draft genome. Analysis suggests the presence of genes for tolerance to cold and toxic metals, broad carbohydrate metabolism, and genes derived from phage. Copyright © 2015 Hyson et al.

[Isolation and identification of cow-origin Cryptosporidium isolates in Hefei].

Science.gov (United States)

Sun, Tao; Liu, Wei; Wang, Ju-Hua; Xue, Xiu-Heng; Zhao, Chang-Cheng; Li, Pei-Ying

2011-12-01

To isolate cow-origin Cryptosporidium in Hefei, and identify its species. 285 dairy cattle fecal samples collected from a farm in Hefei were examined by using floating saturated solution of sucrose and modified acid-fast staining. Cryptosporidium oocysts were isolated and purified from positive fecal samples. Genetic DNA was extracted to be the template. According to the sequence of 18S rRNA gene and HSP70 gene from Cryptosporidium sp., the primers were designed and synthesized. The PCR products were amplified by PCR and nested-PCR. The nested PCR products were cloned and sequenced. Homology searches and phylogenic tree construction were done by DNAStar software. Five fecal samples were positive by morphological methods with an infection rate of 1.8% (5/285). Oocysts from the 5 positive fecal samples were elliptical or ovoid detected by using floating saturated solution of sucrose and modified acid-fast staining with the size of 7.37 microm x 6.13 microm and 7.58 microm x 6.20 microm, and a shape index of 1.20 and 1.22, respectively. Nested-PCR resulted in a 18S rRNA and HSP70 gene fragments with approximately 250 bp and 325 bp, respectively. The five isolates showed a high level of nucleic acid identity with sequence data of the 18S rRNA gene of Cryptosporidium andersoni (DQ989573), and they were clustered in the same clade. The highest HSP70 gene sequence identity was found among the five isolates and other reported C. andersoni isolates (AY954892 and DQ989576), and they were placed into the same clade. The cow-origin Cryptosporidium isolates derived from Hefei is Cryptosporidium andersoni.

Operational Experience from Solar Thermal Energy Projects

Science.gov (United States)

Cameron, C. P.

1984-01-01

Over the past few years, Sandia National Laboratories were involved in the design, construction, and operation of a number of DOE-sponsored solar thermal energy systems. Among the systems currently in operation are several industrial process heat projects and the Modular Industrial Solar Retrofit qualification test systems, all of which use parabolic troughs, and the Shenandoah Total Energy Project, which uses parabolic dishes. Operational experience has provided insight to both desirable and undesirable features of the designs of these systems. Features of these systems which are also relevant to the design of parabolic concentrator thermal electric systems are discussed. Other design features discussed are system control functions which were found to be especially convenient or effective, such as local concentrator controls, rainwash controls, and system response to changing isolation. Drive systems are also discussed with particular emphasis of the need for reliability and the usefulness of a manual drive capability.

Static and dynamic stability of pneumatic vibration isolators and systems of isolators

Science.gov (United States)

Ryaboy, Vyacheslav M.

2014-01-01

Pneumatic vibration isolation is the most widespread effective method for creating vibration-free environments that are vital for precise experiments and manufacturing operations in optoelectronics, life sciences, microelectronics, nanotechnology and other areas. The modeling and design principles of a dual-chamber pneumatic vibration isolator, basically established a few decades ago, continue to attract attention of researchers. On the other hand, behavior of systems of such isolators was never explained in the literature in sufficient detail. This paper covers a range of questions essential for understanding the mechanics of pneumatic isolation systems from both design and application perspectives. The theory and a model of a single standalone isolator are presented in concise form necessary for subsequent analysis. Then the dynamics of a system of isolators supporting a payload is considered with main attention directed to two aspects of their behavior: first, the static stability of payloads with high positions of the center of gravity; second, dynamic stability of the feedback system formed by mechanical leveling valves. The direct method of calculating the maximum stable position of the center of gravity is presented and illustrated by three-dimensional stability domains; analytic formulas are given that delineate these domains. A numerical method for feedback stability analysis of self-leveling valve systems is given, and the results are compared with the analytical estimates for a single isolator. The relation between the static and dynamic phenomena is discussed.

Waste Isolation Pilot Plant Site Environmental Report for calendar year 1989

International Nuclear Information System (INIS)

1989-01-01

This is the 1989 Site Environmental Report (SER) for the Waste Isolation Pilot Plant (WIPP) in southeastern New Mexico. The WIPP is a government owned and contractor-operated facility. The WIPP project is operated by Westinghouse Electric Corporation for the US Department of Energy (DOE). The mission of the WIPP is to provide a research and development facility to demonstrate the safe disposal of transuranic (TRU) waste generated by the defense activities of the US Government. This report provides a comprehensive description of environmental activities at the WIPP during calendar year 1989. The WIPP facility will not receive waste until all concerns affecting opening the WIPP are addressed to the satisfaction of the Secretary of Energy. Therefore, this report describes the status of the preoperational activities of the Radiological Environmental Surveillance (RES) program, which are outlined in the Radiological Baseline Program for the Waste Isolation Pilot Plant (WTSD-TME-057). 72 refs., 13 figs., 20 tabs

Effect of isolation techniques on the characteristics of pigeon pea (Cajanus cajan) protein isolates

OpenAIRE

Adenekan, Monilola K.; Fadimu, Gbemisola J.; Odunmbaku, Lukumon A.; Oke, Emmanuel K.

2017-01-01

Abstract In this study, the effect of different isolation techniques on the isolated proteins from pigeon pea was investigated. Water, methanol, ammonium sulfate, and acetone were used for the precipitation of proteins from pigeon pea. Proximate composition, and antinutritional and functional properties of the pigeon pea flour and the isolated proteins were measured. Data generated were statistically analyzed. The proximate composition of the water‐extracted protein isolate was moisture 8.30%...

Scenario development for the Waste Isolation Pilot Plant: Building confidence in the assessment

International Nuclear Information System (INIS)

Galson, D.A.; Swift, P.N.

1994-01-01

Scenario developments is part of the iterative performance assessment (PA) process for the Waste Isolation Pilot Plant (WIPP). Scenario development for the WIPP has been the subject of intense external review, and is certain to be the subject of continued scrutiny as the project proceeds toward regulatory compliance. The principal means of increasing confidence is this aspect of the PA will be through the use of a systematic and thorough procedure toward developing the scenarios and conceptual models on which the assessment is to be based. Early and ongoing interaction with project reviewers can assist with confidence building. Quality of argument and clarity of presentation in PA will be of key concern. Appropriate tools are required for documenting and tracking assumptions, through a single assessment phase, and between iterative assessment phases. Risks associated with future human actions are of particular concern to the WIPP project, and international consensus on the principles for incorporation of future human actions in assessments would be valuable

Scenario development for the Waste Isolation Pilot Plant: Building confidence in the assessment

International Nuclear Information System (INIS)

Galson, D.A.; Swift, P.N.

1994-07-01

Scenario development is part of the iterative performance assessment (PA) process for the Waste Isolation Pilot Plant (WIPP). Scenario development for the WIPP has been the subject of intense external review and is certain to be the subject of continued scrutiny as the project proceeds toward regulatory compliance. The principal means of increasing confidence in this aspect of the PA will be through the use of the systematic and thorough procedure toward developing the scenarios and conceptual models on which the assessment is to be based. Early and ongoing interaction with project reviewers can assist with confidence building. Quality of argument and clarity of presentation in PA will be of key concern. Appropriate tools are required for documenting and tracking assumptions, through a single assessment phase, and between iterative assessment phases. Risks associated with future human actions are of particular concern to the WIPP project, and international consensus on the principles for incorporation of future human actions in assessments would be valuable

Operations management system advanced automation: Fault detection isolation and recovery prototyping

Science.gov (United States)

Hanson, Matt

1990-01-01

The purpose of this project is to address the global fault detection, isolation and recovery (FDIR) requirements for Operation's Management System (OMS) automation within the Space Station Freedom program. This shall be accomplished by developing a selected FDIR prototype for the Space Station Freedom distributed processing systems. The prototype shall be based on advanced automation methodologies in addition to traditional software methods to meet the requirements for automation. A secondary objective is to expand the scope of the prototyping to encompass multiple aspects of station-wide fault management (SWFM) as discussed in OMS requirements documentation.

Analysis of the possibility of isolation of radioactive wastes of Chernobyl nuclear power plant into the deep drills of the Korosten crystalline rocks

International Nuclear Information System (INIS)

Shestopalov, V.; Kedrovsky, O.; Shishits, I.

1996-01-01

The aim of the offered research: - investigation and proving the possibility to isolate the radioactive wastes (RAW), that were created as a result of the Chernobyl accident, its operation, and shutting down, by placing the wastes into the chinks of the depth up to 4 km. The chinks are supposed to be made in the crystalline rocks of the Korosten massif located near of the Chernobyl NPP. - developing of the basis of the technology and fulfilling the designing work for isolation the RAW in the deep chinks. The basic aims of the researches of the project are the following : Finding out the location of a suitable place. The Ukraine plate's territory (having non-deep occurrences of the crystalline rocks that are minimally subjected to the tectonic destroying), near of the Chernobyl NPP, would be investigated. To solve the problem , the decoding of the aero- and space-photos, geophysical and indicating works, testing drilling of non-deep chinks, and testing works in it have to be done. So, during of the carrying out the project , the following points would be developed: - the geological grounds for creating the RAW isolating system in the deep chinks (taking the conditions at the Nuclear Power Plant), - the best design of the deep chink, - the technology of isolating the RAW in the deep chinks, - the requirements on the monitoring, - the estimations of the ecological safety and efficiency of the chink type systems for RAW isolating

SPI Conformance Gel Applications in Geothermal Zonal Isolation

Energy Technology Data Exchange (ETDEWEB)

Burns, Lyle [Clean Tech Innovations, Bartlesville, OK (United States)

2017-08-08

Zonal isolation in geothermal injection and producing wells is important while drilling the wells when highly fractured geothermal zones are encountered and there is a need to keep the fluids from interfering with the drilling operation. Department of Energy’s (DOE) Energy Efficiency and Renewable Energy (EERE) objectives are to advance technologies to make it more cost effective to develop, produce, and monitor geothermal reservoirs and produce geothermal energy. Thus, zonal isolation is critical to well cost, reservoir evaluation and operations. Traditional cementing off of the lost circulation or thief zones during drilling is often done to stem the drilling mud losses. This is an expensive and generally unsuccessful technique losing the potential of the remaining fracture system. Selective placement of strong SPI gels into only the offending fractures can maintain and even improve operational efficiency and resource life. The SPI gel system is a unique silicate based gel system that offers a promising solution to thief zones and conformance problems with water and CO2 floods and potentially geothermal operations. This gel system remains a low viscosity fluid until an initiator (either internal such as an additive or external such as CO2) triggers gelation. This is a clear improvement over current mechanical methods of using packers, plugs, liners and cementing technologies that often severely damage the highly fractured area that is isolated. In the SPI gels, the initiator sets up the fluid into a water-like (not a precipitate) gel and when the isolated zone needs to be reopened, the SPI gel may be removed with an alkaline solution without formation damage occurring. In addition, the SPI gel in commercial quantities is expected to be less expensive than competing mechanical systems and has unique deep placement possibilities. This project seeks to improve upon the SPI gel integrity by modifying the various components to impart temperature stability for use in

Tomographic image via background subtraction using an x-ray projection image and a priori computed tomography

International Nuclear Information System (INIS)

Zhang Jin; Yi Byongyong; Lasio, Giovanni; Suntharalingam, Mohan; Yu, Cedric

2009-01-01

Kilovoltage x-ray projection images (kV images for brevity) are increasingly available in image guided radiotherapy (IGRT) for patient positioning. These images are two-dimensional (2D) projections of a three-dimensional (3D) object along the x-ray beam direction. Projecting a 3D object onto a plane may lead to ambiguities in the identification of anatomical structures and to poor contrast in kV images. Therefore, the use of kV images in IGRT is mainly limited to bony landmark alignments. This work proposes a novel subtraction technique that isolates a slice of interest (SOI) from a kV image with the assistance of a priori information from a previous CT scan. The method separates structural information within a preselected SOI by suppressing contributions to the unprocessed projection from out-of-SOI-plane structures. Up to a five-fold increase in the contrast-to-noise ratios (CNRs) was observed in selected regions of the isolated SOI, when compared to the original unprocessed kV image. The tomographic image via background subtraction (TIBS) technique aims to provide a quick snapshot of the slice of interest with greatly enhanced image contrast over conventional kV x-ray projections for fast and accurate image guidance of radiation therapy. With further refinements, TIBS could, in principle, provide real-time tumor localization using gantry-mounted x-ray imaging systems without the need for implanted markers.

SUSCEPTIBILITY OF RESPIRATORY ISOLATES OF STREPTOCOCCUS PNEUMONIAE ISOLATED FROM CHILDREN HOSPITALIZED IN THE CLINICAL CENTER NIS.

Science.gov (United States)

Dinić, Marina M; Mladenović Antić, Snezana; Kocić, Branislava; Stanković Dordević, Dobrila; Vrbić, Miodrag; Bogdanović, Milena

2016-01-01

Streptococcus pneumoniae is one of the most common causes of respiratory infections. The aim was to study the susceptibility to antimicrobial agents of respiratory isolates ofStreptococcus pneumoniae obtained from hospitalized children. A total of 190 respiratory pneumococcal isolates obtained from children aged from 0 to 14 years were isolated and identified by using standard microbiological methods. Susceptibility to oxacillin, erythromycin, clindamycin, tetracycline, cotrimoxazole, ofloxacin and rifampicin was tested by disc diffusion method. Minimal inhibitory concentrations for amoxicillin and ceftriaxone were determined by means of E test. The macrolide-resistant phenotype was detected by double disc diffusion test. All tested isolates were susceptible to amoxicillin and ceftriaxone. The minimal amoxicillin concentration inhibiting the growth of 50% of isolates and of 90% of isolates was 0.50 microg/ml and 1.0 microg/ml, respectively and the minimal ceftriaxone concentration inhibiting the growth of 50% of isolates and of 90% of isolates was 0.25 microg/ml and 0.50 microg/ml, respectively. Susceptibility to erythromycin and clindamycin was observed in 21.6% and 29.47% of isolates, respectively. The resistence to macrolides-M phenotype was detected in 10.07% of isolates and constitutive macrolide-lincosamide-streptogramin phenotype (constitutive MLS phenotype) was found in 89.93% of isolates. All tested isolates were susceptible to ofloxacin and rifampicin. Amoxicillin could be the therapy of choice in pediatric practice. The macrolides should not be recommended for the empirical therapy of pneumococcal respiratory tract infection in our local area.

Three-dimensional morphology of the palate in subjects with isolated cleft palate at the stage of permanent dentition

Czech Academy of Sciences Publication Activity Database

Šmahel, Zbyněk; Trefný, P.; Formánek, P.; Müllerová, Ž.; Peterka, Miroslav

2003-01-01

Roč. 40, č. 6 (2003), s. 577-584 ISSN 1055-6656 R&D Projects: GA ČR GA304/99/0891 Institutional research plan: CEZ:AV0Z5039906 Keywords : fourier transform profilometry * isolated cleft palate * palatal morphology Subject RIV: FF - HEENT, Dentistry Impact factor: 0.888, year: 2003

Magnetic hydrophilic poly(2-hydroxyethyl methacrylate-co-glycidyl methacrylate) microspheres for DNA isolation from faeces

Czech Academy of Sciences Publication Activity Database

Trachtová, Š.; Obermajer, T.; Španová, A.; Matijašić, B. B.; Rogelj, I.; Horák, Daniel; Rittich, B.

2012-01-01

Roč. 555, č. 1 (2012), s. 263-270 ISSN 1542-1406. [International Conference on Frontiers of Polymers and Advanced Materials /11./. Pretoria, 22.05.2011-27.05.2011] R&D Projects: GA MŠk 2B06053 Institutional research plan: CEZ:AV0Z40500505 Keywords : DNA isolation * magnetic microspheres * mouse faeces Subject RIV: EE - Microbiology, Virology Impact factor: 0.530, year: 2012

Yeast Isolation for Bioethanol Production

Directory of Open Access Journals (Sweden)

EKA RURIANI

2012-09-01

Full Text Available We have isolated 12 yeast isolates from five different rotten fruits by using a yeast glucose chloramphenicol agar (YGCA medium supplemented with tetracycline. From pre-screening assay, four isolates exhibited higher substrate (glucose-xylose consumption efficiency in the reaction tube fermentation compared to Saccharomyces cerevisiae dan Saccharomyces ellipsoids as the reference strains. Based on the fermentation process in gooseneck flasks, we observed that two isolates (K and SB showed high fermentation efficiency both in sole glucose and mixed glucose-xylose substrate. Moreover, isolates K and SB produced relatively identical level of ethanol concentration compared to the reference strains. Isolates H and MP could only produce high levels of ethanol in glucose fermentation, while only half of that amount of ethanol was detected in glucose-xylose fermentation. Isolate K and SB were identified as Pichia kudriavzeevii (100% based on large sub unit (LSU ribosomal DNA D1/D2 region.

Isolation, characterization, antibiogram and pathology of Pasteurella multocida isolated from pigs

Directory of Open Access Journals (Sweden)

Mamta Tigga

2014-05-01

Full Text Available Aim: Isolation, characterization and antibiogram of Pasteurella multocida from diseased pigs of district Durg of Chhattisgarh, and to study pathological changes caused by swine pasteurellosis. Materials and Methods: An outbreak of swine pasteurellosis was suspected in pigs of Ruwabandha (Bhilai, Anjora, Somni, Tedesara, Tirgajhola villages of Durg district in Chhattisgarh, India during August and September of 2011. Nasal Swabs and blood samples from ailing pigs and heart blood and impression smears from morbid pigs were processed for detection and isolation of P. multocida by bacteriological methods. Detailed necropsy was conducted and gross and histopathological lesions were recorded. The test Isolates were subjected to antimicrobial sensitivity profile by disc-diffusion method. Results: The blood smears from heart blood and tissue impression smears revealed teaming of bipolar organisms indicating the presence of Pasteurella spp. The isolates obtained were subjected to Gram's staining for checking the purity and bipolar morphology and characterized biochemically. Gross lesions included severe acute pneumonia and haemorrhages in lungs, petechial haemorrhages on serous membranes and other visceral organs. On histopathological examination, lungs showed typical fibrinous bronchopneumonia, multifocal suppuration. All the isolates of P. multocida were 100% sensitive to Amoxicillin, Gentamicin, Enrofloxacin and showed100% resistance to Ceftizoxim and Cloxacillin. Conclusion: Gross and microscopic lesions in dead animals are of great diagnostic value and are of characteristic of P. multocida infection. Cultural, morphological and biochemical characters are useful to rule out the causative agent as P. multocida. Antibiotic sensitivity pattern of the isolates should routinely be carried out for knowing the antibiotic resistance trends in an endemic area.

Active Fault Isolation in MIMO Systems

DEFF Research Database (Denmark)

Niemann, Hans Henrik; Poulsen, Niels Kjølstad

2014-01-01

isolation is based directly on the input/output s ignals applied for the fault detection. It is guaranteed that the fault group includes the fault that had occurred in the system. The second step is individual fault isolation in the fault group . Both types of isolation are obtained by applying dedicated......Active fault isolation of parametric faults in closed-loop MIMO system s are considered in this paper. The fault isolation consists of two steps. T he first step is group- wise fault isolation. Here, a group of faults is isolated from other pos sible faults in the system. The group-wise fault...

Single spore isolation and morphological characterization of local Malaysian isolates of rice blast fungus Magnoporthe grisea

Science.gov (United States)

Mishra, Ankitta; Ratnam, Wickneswari; Bhuiyan, Md Atiqur Rahman; Ponaya, Ariane; Jena, Khisord K.

2015-09-01

Rice blast is a destructive disease, caused by the fungal pathogen Magnaporthe grisea. It causes considerable damage to rice and leads to crop loss in rice growing regions worldwide. Although fungicides can be used to control rice blast, they generate additional cost in rice production and contamination of environment and food. Therefore, the use of resistant varieties is thought to be one of the most economically and environmentally efficient ways of crop protection from the disease. Six new local Malaysian isolates of M. grisea were isolated using single spore isolation method. Five isolates were from infected leaf samples collected from Kompleks Latihan MADA, Kedah and one was from Kelantan. These isolates were identified using morphological characteristics and microscopic studies and later confirmed by ITSequences. These isolates were induced to sporulate and used for greenhouse screening on two differential rice varieties: Mahsuri (susceptible) and Pongsu Seribu 2 (resistant). Among the 6 isolates, isolate number 3 was found to be the most virulent showing high sporulation while isolate number 4 was very slow growing, and the least virulent.

Reliability analysis of containment isolation systems

International Nuclear Information System (INIS)

Pelto, P.J.; Ames, K.R.; Gallucci, R.H.

1985-06-01

This report summarizes the results of the Reliability Analysis of Containment Isolation System Project. Work was performed in five basic areas: design review, operating experience review, related research review, generic analysis and plant specific analysis. Licensee Event Reports (LERs) and Integrated Leak Rate Test (ILRT) reports provided the major sources of containment performance information used in this study. Data extracted from LERs were assembled into a computer data base. Qualitative and quantitative information developed for containment performance under normal operating conditions and design basis accidents indicate that there is room for improvement. A rough estimate of overall containment unavailability for relatively small leaks which violate plant technical specifications is 0.3. An estimate of containment unavailability due to large leakage events is in the range of 0.001 to 0.01. These estimates are dependent on several assumptions (particularly on event duration times) which are documented in the report

Limnohabitans australis sp. nov., isolated from a freshwater pond, and emended description of the genus Limnohabitans

Czech Academy of Sciences Publication Activity Database

Hahn, M.W.; Kasalický, Vojtěch; Jezbera, Jan; Brandt, U.; Šimek, Karel

2010-01-01

Roč. 60, č. 12 (2010), s. 2946-2950 ISSN 1466-5026 R&D Projects: GA MŠk(CZ) MEB060702; GA ČR(CZ) GA206/08/0015 Institutional research plan: CEZ:AV0Z60170517; CEZ:AV0Z60660521 Keywords : bacterium isolate * Betaproteobacteria * freshwater species * microbiology * Limnohabitans Subject RIV: EE - Microbiology, Virology Impact factor: 1.930, year: 2010

Bacterial isolates from the bryozoan Membranipora membranacea: influence of culture media on isolation and antimicrobial activity.

Science.gov (United States)

Heindl, Herwig; Thiel, Vera; Wiese, Jutta; Imhoff, Johannes F

2012-03-01

From specimens of the bryozoan Membranipora membranacea collected in the Baltic Sea, bacteria were isolated on four different media, which significantly increased the diversity of the isolated groups. All isolates were classified according to 16S rRNA gene sequence analysis and tested for antimicrobial properties using a panel of five indicator strains and six different media. Each medium featured a unique set of isolated phylotypes, and a phylogenetically diverse collection of isolates was obtained. A total of 96 isolates were assigned to 49 phylotypes and 29 genera. Only one-third of the members of these genera had been isolated previously from comparable sources. The isolates were affiliated with Alpha- and Gammaproteobacteria, Bacilli, and Actinobacteria. A comparable large portion of up to 22 isolates, i.e., 15 phylotypes, probably represent new species. Likewise, 47 isolates (approximately 50%) displayed antibiotic activities, mostly against grampositive indicator strains. Of the active strains, 63.8 % had antibiotic traits only on one or two of the growth media, whereas only 12.7 % inhibited growth on five or all six media. The application of six different media for antimicrobial testing resulted in twice the number of positive hits as obtained with only a single medium. The use of different media for the isolation of bacteria as well as the variation of media considered suitable for the production of antibiotic substances significantly enhanced both the number of isolates obtained and the proportion of antibiotic active cultures. Thus the approach described herein offers an improved strategy in the search for new antibiotic compounds.

Is Project Towards No Drug Abuse (Project TND) an evidence-based drug and violence prevention program? A review and reappraisal of the evaluation studies.

Science.gov (United States)

Gorman, Dennis M

2014-08-01

This paper critically reviews the published evidence pertaining to Project Towards No Drug Abuse (Project TND). Publications from seven evaluation studies of Project TND are reviewed, and the results from these are discussed as related to the following outcomes: main effects on the use of cigarettes, alcohol and marijuana; main effects on the use of "hard drugs," defined in the evaluations as cocaine, hallucinogens, stimulants, inhalants, ecstasy and other drugs (e.g., depressants, PCP, steroids and heroin); subgroup and interaction analyses of drug use; and violence-related behaviors. Very few main effects have been found for cigarette, alcohol and marijuana use in the Project TND evaluations. While studies do report main effects for hard drug use, these findings are subject to numerous threats to validity and may be attributable to the data analyses employed. Similarly, while isolated subgroup and interaction effects were found for alcohol use among baseline nonusers and some violence-related behaviors in the early Project TND evaluations, these findings have not been replicated in more recent studies and may result from multiple comparisons between study conditions. In conclusion, there is little evidence to support the assertion that Project TND is an effective drug or violence prevention program. The broader implications of these findings for prevention science are discussed and suggestions are made as to how the quality of research in the field might be improved.

A portfolio evaluation framework for air transportation improvement projects

Science.gov (United States)

Baik, Hyeoncheol

This thesis explores the application of portfolio theory to the Air Transportation System (ATS) improvement. The ATS relies on complexly related resources and different stakeholder groups. Moreover, demand for air travel is significantly increasing relative to capacity of air transportation. In this environment, improving the ATS is challenging. Many projects, which are defined as technologies or initiatives, for improvement have been proposed and some have been demonstrated in practice. However, there is no clear understanding of how well these projects work in different conditions nor of how they interact with each other or with existing systems. These limitations make it difficult to develop good project combinations, or portfolios that maximize improvement. To help address this gap, a framework for identifying good portfolios is proposed. The framework can be applied to individual projects or portfolios of projects. Projects or portfolios are evaluated using four different groups of factors (effectiveness, time-to-implement, scope of applicability, and stakeholder impacts). Portfolios are also evaluated in terms of interaction-determining factors (prerequisites, co-requisites, limiting factors, and amplifying factors) because, while a given project might work well in isolation, interdependencies between projects or with existing systems could result in lower overall performance in combination. Ways to communicate a portfolio to decision makers are also introduced. The framework is unique because (1) it allows using a variety of available data, and (2) it covers diverse benefit metrics. For demonstrating the framework, an application to ground delay management projects serves as a case study. The portfolio evaluation approach introduced in this thesis can aid decision makers and researchers at universities and aviation agencies such as Federal Aviation Administration (FAA), National Aeronautics and Space Administration (NASA), and Department of Defense (DoD), in

Global survey of Klebsiella pneumoniae major porins from ertapenem non-susceptible isolates lacking carbapenemases.

Science.gov (United States)

Wise, Mark G; Horvath, Elizabeth; Young, Katherine; Sahm, Daniel F; Kazmierczak, Krystyna M

2018-03-01

To understand the diversity of porin disruption in Klebsiella pneumoniae, the major outer membrane protein (OMP) porins, OmpK35 and OmpK36, were examined in a set of isolates that did not harbour traditional carbapenem-hydrolysing enzymes, but nevertheless tested non-susceptible to ertapenem. A world-wide collection of Klebsiella pneumoniae isolates that were part of the Study for Monitoring Antimicrobial Resistance Trends (SMART) surveillance project over the years 2008-2014 were characterised with regard to their β-lactamase gene carriage and potential permeability defects. Four hundred and eighty-seven isolates that did not carry carbapenemase genes, but were non-susceptible to ertapenem, were investigated by sequence analysis of the genes encoding OmpK35 and OmpK36. Isolates without obvious genetic lesions in either major porin gene were further examined by outer membrane protein SDS-PAGE. The majority of isolates, 83.0 % (404/487), exhibited clear genetic disruption in either or both of the ompK35 and ompK36 genes. Among the proportion of the collection with the highest ertapenem MIC value (>4 mg l -1 ), 60.5 % (115/190) showed mutation in both porin genes. Isolates without obvious genetic mutations were examined by SDS-PAGE, and 90.4 % (75/83) were found to lack or show altered expression of at least one of the major OMPs when compared to an ertapenem sensitive control strain. This study illustrates that porin deficiency in Klebsiella pneumoniae is a widespread phenomenon, and in combination with ESBLs and/or AmpC enzymes, likely accounts for the elevated ertapenem MICs observed in this study.

Application UPTASK project management platform to support management decisions in I.T.

Directory of Open Access Journals (Sweden)

Lagerev D.G.

2017-03-01

Full Text Available Project planning and management accounting of all factors, in terms of multitasking and spontaneity of project man-agement, the task is very voluminous and complex, especially in isolation from the methodological and instrumentation. Calculation of indicators and statistical metrics, and strategies, the decision maker may be biased or incorrect character, and one can’t exclude the human factor. In such a perspective, it was decided to automate the process of statistical anal-ysis and probabilistic forecasting to help the decision-maker, as much as the right choice of strategic and project plan-ning. The problem is solved by means of the development of the project management system for the companies of the areas of information technology. One of the most important features of the development of a module statistical and probabilistic analysis based on Bayesian networks. The use of the proposed tool and methodological complex, will pro-vide a high level of optimization of the allocation of time to work processes and will increase the degree of correctness and continuity of decisions taken by the project manager.

Study of Collaborative Management for Transportation Construction Project Based on BIM Technology

Science.gov (United States)

Jianhua, Liu; Genchuan, Luo; Daiquan, Liu; Wenlei, Li; Bowen, Feng

2018-03-01

Abstract. Building Information Modeling(BIM) is a building modeling technology based on the relevant information data of the construction project. It is an advanced technology and management concept, which is widely used in the whole life cycle process of planning, design, construction and operation. Based on BIM technology, transportation construction project collaborative management can have better communication through authenticity simulation and architectural visualization and can obtain the basic and real-time information such as project schedule, engineering quality, cost and environmental impact etc. The main services of highway construction management are integrated on the unified BIM platform for collaborative management to realize information intercommunication and exchange, to change the isolated situation of information in the past, and improve the level of information management. The final BIM model is integrated not only for the information management of project and the integration of preliminary documents and design drawings, but also for the automatic generation of completion data and final accounts, which covers the whole life cycle of traffic construction projects and lays a good foundation for smart highway construction.

Biodiversity and ochratoxin A profile of Aspergillus section Nigri populations isolated from wine grapes in Cyprus vineyards.

Science.gov (United States)

Pantelides, Iakovos S; Aristeidou, Efi; Lazari, Maria; Tsolakidou, Maria-Dimitra; Tsaltas, Dimitris; Christofidou, Maria; Kafouris, Demetris; Christou, Eftychia; Ioannou, Nicolas

2017-10-01

The objective of this study was to evaluate the biodiversity of Aspergillus section Nigri populations from Cyprus vineyards by morphological, toxigenic and phylogenetic analysis. Aspergillus section Nigri populations were isolated from grapes of the varieties 'Maratheftiko' and 'Cabernet Sauvignon' originating from six growing regions of Cyprus during 2010 and 2011 years. The isolation frequency of Aspergillus section Nigri from grape samples was 43.3% and a total of 284 isolates were selected for further analyses based on the macroscopic characteristics of black aspergilli. The isolates were characterized by sequencing analysis of the calmodulin gene in order to identify species responsible for ochratoxin A (OTA) production. The phylogenetic analysis showed that the isolates were grouped in three major clusters. The A. tubingensis cluster included 262 isolates (92.25%), the A. niger cluster included 15 isolates identified as A. niger (5.3%) and 6 isolates identified as A. welwitschiae (2.1%). One isolate was classified as A. carbonarius (0.35%) and was grouped in a cluster together with the reference isolates of A. carbonarius, A. sclerotioniger, A. sclerotiocarbonarius and A. ibericus. All the isolates were evaluated for their ochratoxigenic ability by HPLC coupled with a fluorescence detector (HPLC-FLD) and the positive isolates were re-examined using ultra high-performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS). The Aspergillus carbonarius isolate produced an average quantity of 1436.1 ng OTA/g Czapek Yeast Agar (CYA); From the A. niger strains three isolates (20%) produced OTA and only one isolate from A. welwitschiae (16.7%) was proved ochratoxigenic with toxin production average at 23.9 ng/g and 9.1 ng/g CYA respectively. Grape must samples derived from the collected berries were also analyzed for OTA and none of the samples were found contaminated with the mycotoxin. The results showed that the geographic area and the

Incipient Fault Detection and Isolation of Field Devices in Nuclear Power Systems Using Principal Component Analysis

International Nuclear Information System (INIS)

Kaistha, Nitin; Upadhyaya, Belle R.

2001-01-01

An integrated method for the detection and isolation of incipient faults in common field devices, such as sensors and actuators, using plant operational data is presented. The approach is based on the premise that data for normal operation lie on a surface and abnormal situations lead to deviations from the surface in a particular way. Statistically significant deviations from the surface result in the detection of faults, and the characteristic directions of deviations are used for isolation of one or more faults from the set of typical faults. Principal component analysis (PCA), a multivariate data-driven technique, is used to capture the relationships in the data and fit a hyperplane to the data. The fault direction for each of the scenarios is obtained using the singular value decomposition on the state and control function prediction errors, and fault isolation is then accomplished from projections on the fault directions. This approach is demonstrated for a simulated pressurized water reactor steam generator system and for a laboratory process control system under single device fault conditions. Enhanced fault isolation capability is also illustrated by incorporating realistic nonlinear terms in the PCA data matrix

Development of a Comprehensive Plan for Scientific Research, Exploration, and Design: Creation of an Underground Radioactive Waste Isolation Facility at the Nizhnekansky Rock Massif

International Nuclear Information System (INIS)

Jardine, L J

2005-01-01

ISTC Partner Project No.2377, ''Development of a General Research and Survey Plan to Create an Underground RW Isolation Facility in Nizhnekansky Massif'', funded a group of key Russian experts in geologic disposal, primarily at Federal State Unitary Enterprise All-Russian Design and Research Institute of Engineering Production (VNIPIPT) and Mining Chemical Combine Krasnoyarsk-26 (MCC K-26) (Reference 1). The activities under the ISTC Partner Project were targeted to the creation of an underground research laboratory which was to justify the acceptability of the geologic conditions for ultimate isolation of high-level waste in Russia. In parallel to this project work was also under way with Minatom's financial support to characterize alternative sections of the Nizhnekansky granitoid rock massif near the MCC K-26 site to justify the possibility of creating an underground facility for long-term or ultimate isolation of radioactive waste (RW) and spent nuclear fuel (SNF). (Reference 2) The result was a synergistic, integrated set of activities several years that advanced the geologic repository site characterization and development of a proposed underground research laboratory better than could have been expected with only the limited funds from ISTC Partner Project No.2377 funded by the U.S. DOE-RW. There were four objectives of this ISTC Partner Project 2377 geologic disposal work: (1) Generalize and analyze all research work done previously at the Nizhnekansky granitoid massif by various organizations; (2) Prepare and issue a declaration of intent (DOI) for proceeding with an underground research laboratory in a granite massif near the MCC K-26 site. (The DOI is similar to a Record of Decision in U.S. terminology). (3) Proceeding from the data obtained as a result of scientific research and exploration and design activities, prepare a justification of investment (JOI) for an underground research laboratory in as much detail as the available site characterization

Waste Isolation Pilot Plant Groundwater Protection Management Program Plan

Energy Technology Data Exchange (ETDEWEB)

Washington TRU Solutions

2002-09-24

U.S. Department of Energy (DOE) Order 5400.1, General Environmental Protection Program, requires each DOE site to prepare a Groundwater Protection Management Program Plan. This document fulfills the requirement for the Waste Isolation Pilot Plant (WIPP). This document was prepared by the Hydrology Section of the Westinghouse TRU Solutions LLC (WTS) Environmental Compliance Department, and it is the responsibility of this group to review the plan annually and update it every three years. This document is not, nor is it intended to be, an implementing document that sets forth specific details on carrying out field projects or operational policy. Rather, it is intended to give the reader insight to the groundwater protection philosophy at WIPP.

Isolation & characterization of Brucella melitensis isolated from patients suspected for human brucellosis in India

Science.gov (United States)

Barua, Anita; Kumar, Ashu; Thavaselvam, Duraipandian; Mangalgi, Smita; Prakash, Archana; Tiwari, Sapana; Arora, Sonia; Sathyaseelan, Kannusamy

2016-01-01

Background & objectives: Brucellosis is endemic in the southern part of India. A combination of biochemical, serological and molecular methods is required for identification and biotyping of Brucella. The present study describes the isolation and biochemical, molecular characterization of Brucella melitensis from patients suspected for human brucellosis. Methods: The blood samples were collected from febrile patients suspected to have brucellosis. A total of 18 isolates were obtained from 102 blood samples subjected to culture. The characterization of these 18 isolates was done by growth on Brucella specific medium, biochemical reactions, CO2 requirement, H2S production, agglutination with A and M mono-specific antiserum, dye sensitivity to basic fuchsin and thionin. Further, molecular characterization of the isolates was done by amplification of B. melitensis species specific IS711 repetitive DNA fragment and 16S (rRNA) sequence analysis. PCR-restriction fragment length polymorphism (RFLP) analysis of omp2 locus and IS711 gene was also done for molecular characterization. Results: All 102 suspected samples were subjected to bacteria isolation and of these, 18 isolates could be recovered on blood culture. The biochemical, PCR and PCR-RFLP and 16s rRNA sequencing revealed that all isolates were of B. melitensis and matched exactly with reference strain B. melitensis 16M. Interpretation & conclusions: The present study showed an overall isolation rate of 17.64 per cent for B. melitensis. There is a need to establish facilities for isolation and characterization of Brucella species for effective clinical management of the disease among patients as well as surveillance and control of infection in domestic animals. Further studies are needed from different geographical areas of the country with different level of endemicity to plan and execute control strategies against human brucellosis. PMID:27488010

Isolation and screening of azo dye decolorizing bacterial isolates from dye-contaminated textile wastewater

Directory of Open Access Journals (Sweden)

Shahid Mahmood

2011-04-01

Full Text Available Azo dyes are released into wastewater streams without any pretreatment and pollute water and soilenvironments. To prevent contamination of our vulnerable resources, removal of these dye pollutants is of greatimportance. For this purpose, wastewater samples were collected from dye-contaminated sites of Faisalabad. About200 bacterial isolates were isolated through enrichment and then tested for their potential to remove RemazolBlack-B azo dye in liquid medium. Five bacterial isolates capable of degrading Remazol Black-B azo dye efficientlywere screened through experimentation on modified mineral salt medium. Isolate SS1 (collected from wastewater ofSupreme Textile Industry was able to completely remove the Remazol Black-B dye from the liquid medium in 18 h.Further, the isolate showed the best performance at the dye concentration of 100 mg L-1 medium (pH 7 and attemperature 35oC. Similarly, yeast extract proved to be the best carbon source for decolorization purpose. Theresults imply that the isolate SS1 could be used for the removal of the reactive dyes from textile effluents.

Review of nuclear waste isolation

International Nuclear Information System (INIS)

Richard, B.H.

1978-06-01

On Jun 22 and 23, 1978, Rockwell Hanford Operations assembled a committee of their personnel, subcontractors, and representatives of other waste isolation programs for a review of nuclear waste isolation. Appendix A lists the participants and their affiliations; Appendix B indicates the agenda. The purpose of the review was to gather experts in the areas pertaining to isolation of nuclear waste to discuss three basic issues that must be addressed in isolation studies. These were: the paths of transport to the biosphere; the barriers needed for containment; and the isolation time necessary for each radioactive isotope. In that these issues are media dependent, the basalt medium was emphasized. Conclusions of the review are described

Recent results of seismic isolation study in CRIEPI: Tests on seismic isolation elements, vibration tests and observations

International Nuclear Information System (INIS)

Ishida, Katsuhiko; Shiojiri, Hiroo; Mazda, Taiji; Ohtori, Yasuki; Aoyagi, Sakae

1992-01-01

Seismic isolation is expected to be effective in raising reliability during earthquake, reducing cost, enlarging and promoting the design standardization of electric power facilities. In Japan, it has been applied to several buildings. However it is considered that more research is needed to verify the reliability and effectiveness of seismic isolation for fast breeder reactors. In the preliminary study of isolation concepts for FBRs the horizontal base isolation of buildings was investigated in detail. The laminated rubber bearings were considered to be most suitable isolation system. Tests on large scale models of rubber bearing and vibration test of base isolation system have been conducted as well as the earthquake response observation of isolated buildings were conducted

Recent results of seismic isolation study in CRIEPI: Tests on seismic isolation elements, vibration tests and observations

Energy Technology Data Exchange (ETDEWEB)

Ishida, Katsuhiko; Shiojiri, Hiroo; Mazda, Taiji; Ohtori, Yasuki [Abiko Research Laboratory, Central Research Institute of Electric Power Industry (Japan); Aoyagi, Sakae [Central Research Institute of Electric Power Industry (Japan)

1992-07-01

Seismic isolation is expected to be effective in raising reliability during earthquake, reducing cost, enlarging and promoting the design standardization of electric power facilities. In Japan, it has been applied to several buildings. However it is considered that more research is needed to verify the reliability and effectiveness of seismic isolation for fast breeder reactors. In the preliminary study of isolation concepts for FBRs the horizontal base isolation of buildings was investigated in detail. The laminated rubber bearings were considered to be most suitable isolation system. Tests on large scale models of rubber bearing and vibration test of base isolation system have been conducted as well as the earthquake response observation of isolated buildings were conducted.

Social isolation reduces serotonergic fiber density in the inferior colliculus of female, but not male, mice.

Science.gov (United States)

Keesom, Sarah M; Morningstar, Mitchell D; Sandlain, Rebecca; Wise, Bradley M; Hurley, Laura M

2018-05-12

Early-life experiences, including maternal deprivation and social isolation during adolescence, have a profound influence on a range of adult social behaviors. Post-weaning social isolation in rodents influences behavior in part through the alteration of neuromodulatory systems, including the serotonergic system. Of significance to social behavior, the serotonergic system richly innervates brain areas involved in vocal communication, including the auditory system. However, the influence of isolation on serotonergic input to the auditory system remains underexplored. Here, we assess whether 4 weeks of post-weaning individual housing alters serotonergic fiber density in the inferior colliculus (IC), an auditory midbrain nucleus in which serotonin alters auditory-evoked activity. Individually housed male and female mice were compared to conspecifics housed socially in groups of three. Serotonergic projections were subsequently visualized with an antibody to the serotonin transporter, which labels serotonergic fibers with relatively high selectivity. Fiber densities were estimated in the three major subregions of the IC using line-scan intensity analysis. Individually housed female mice showed a significantly reduced fiber density relative to socially housed females, which was accompanied by a lower body weight in individually housed females. In contrast, social isolation did not affect serotonergic fiber density in the IC of males. This finding suggests that sensitivity of the serotonergic system to social isolation is sex-dependent, which could be due to a sex difference in the effect of isolation on psychosocial stress. Since serotonin availability depends on social context, this finding further suggests that social isolation can alter the acute social regulation of auditory processing. Copyright © 2018. Published by Elsevier B.V.

Inhibition of Clostridium activities in silage and cheese using anticlostridial Lactobacillus Isolated from Danish semi-hard cheese

DEFF Research Database (Denmark)

Christiansen, Pia

Growth of Clostridium, originating mainly from silage, may cause serious late blowing defects in semi-hard cheeses during ripening. In the present project, the possibilities were investigated to use anticlostridial non-starter Lactobacillus (mainly Lb. paracasei), isolated from Danish semi......-hard cheeses of high quality, as protective adjunct cultures against clostridia activities in silage and cheese. Screening for anticlostridial activity among non-starter Lactobacillus isolates against selected Clostridium strains showed that almost half (44%) of the naturally occurring non......-starter Lactobacillus in Danish semi-hard cheeses possessed anticlostridial activities and 10% possessed a broad anticlostridial activity, and these were selected for further investigations. Antagonistic antimicrobial interactions between some of the selected anticlostridial Lactobacillus strains were demonstrated...

The Neuroendocrinology of Social Isolation

Science.gov (United States)

Cacioppo, John T.; Cacioppo, Stephanie; Capitanio, John P.; Cole, Steven W.

2016-01-01

Social isolation has been recognized as a major risk factor for morbidity and mortality in humans for more than a quarter of a century. Although the focus of research has been on objective social roles and health behavior, the brain is the key organ for forming, monitoring, maintaining, repairing, and replacing salutary connections with others. Accordingly, population-based longitudinal research indicates that perceived social isolation (loneliness) is a risk factor for morbidity and mortality independent of objective social isolation and health behavior. Human and animal investigations of neuroendocrine stress mechanisms that may be involved suggest that (a) chronic social isolation increases the activation of the hypothalamic pituitary adrenocortical axis, and (b) these effects are more dependent on the disruption of a social bond between a significant pair than objective isolation per se. The relational factors and neuroendocrine, neurobiological, and genetic mechanisms that may contribute to the association between perceived isolation and mortality are reviewed. PMID:25148851

The neuroendocrinology of social isolation.

Science.gov (United States)

Cacioppo, John T; Cacioppo, Stephanie; Capitanio, John P; Cole, Steven W

2015-01-03

Social isolation has been recognized as a major risk factor for morbidity and mortality in humans for more than a quarter of a century. Although the focus of research has been on objective social roles and health behavior, the brain is the key organ for forming, monitoring, maintaining, repairing, and replacing salutary connections with others. Accordingly, population-based longitudinal research indicates that perceived social isolation (loneliness) is a risk factor for morbidity and mortality independent of objective social isolation and health behavior. Human and animal investigations of neuroendocrine stress mechanisms that may be involved suggest that (a) chronic social isolation increases the activation of the hypothalamic pituitary adrenocortical axis, and (b) these effects are more dependent on the disruption of a social bond between a significant pair than objective isolation per se. The relational factors and neuroendocrine, neurobiological, and genetic mechanisms that may contribute to the association between perceived isolation and mortality are reviewed.

Perspective of the Science Advisor to the Waste Isolation Pilot Plant

International Nuclear Information System (INIS)

WEART, WENDELL D.

1999-01-01

In 1975 Sandia National Laboratories (SNL) was asked by the predecessor to the Department of Energy to assume responsibility for the scientific programs necessary to assure the safe and satisfactory development of a geologic repository in the salt beds of southeast New Mexico. Sandia has continued in the role of Science Advisor to the Waste Isolation Pilot Plant (WIPP) to the present time. This paper will share the perspectives developed over the past 25 years as the project was brought to fruition with successful certification by the Environmental Protection Agency (EPA) on May 13, 1998 and commencement of operations on April 26, 1999

Uranium Mill Tailings Remedial Action Project, fiscal year 1995 annual report to stakeholders

International Nuclear Information System (INIS)

1995-01-01

In 1978, Congress authorized the DOE to assess and clean up contamination at 24 designated former uranium processing sites. The DOE is also responsible for cleaning up properties in the vicinity of the sites where wind and water erosion deposited tailings or people removed them from the site for use in construction or landscaping projects. Cleanup is being undertaken in cooperation with state governments and Indian tribes within whose boundaries the sites are located. It is being conducted in two phases: the surface project and the ground water project. This report addresses specifics about both phases of the UMTRA Project. DOE's UMTRA Project is the world's largest materials management project ever undertaken to reduce or eliminate risk to the general public from exposure to potentially hazardous and radioactive materials. With an estimated cost at completion of nearly $2 billion for both phases of the UMTRA Project, and with the responsibility for encapsulating and isolating almost one-fourth of all the uranium mill tailings generated across the entire US (more than 44 million cubic yards), the UMTRA Project and its people have achieved a long record of safely and effectively completing its mission. It continually enhances its national reputation through its diligent process and cost efficiency as well as its international recognition for its technological innovation

Discrete optimization of isolator locations for vibration isolation systems: An analytical and experimental investigation

Energy Technology Data Exchange (ETDEWEB)

Ponslet, E.R.; Eldred, M.S. [Sandia National Labs., Albuquerque, NM (United States). Structural Dynamics Dept.

1996-05-17

An analytical and experimental study is conducted to investigate the effect of isolator locations on the effectiveness of vibration isolation systems. The study uses isolators with fixed properties and evaluates potential improvements to the isolation system that can be achieved by optimizing isolator locations. Because the available locations for the isolators are discrete in this application, a Genetic Algorithm (GA) is used as the optimization method. The system is modeled in MATLAB{trademark} and coupled with the GA available in the DAKOTA optimization toolkit under development at Sandia National Laboratories. Design constraints dictated by hardware and experimental limitations are implemented through penalty function techniques. A series of GA runs reveal difficulties in the search on this heavily constrained, multimodal, discrete problem. However, the GA runs provide a variety of optimized designs with predicted performance from 30 to 70 times better than a baseline configuration. An alternate approach is also tested on this problem: it uses continuous optimization, followed by rounding of the solution to neighboring discrete configurations. Results show that this approach leads to either infeasible or poor designs. Finally, a number of optimized designs obtained from the GA searches are tested in the laboratory and compared to the baseline design. These experimental results show a 7 to 46 times improvement in vibration isolation from the baseline configuration.

Robust DNA Isolation and High-throughput Sequencing Library Construction for Herbarium Specimens.

Science.gov (United States)

Saeidi, Saman; McKain, Michael R; Kellogg, Elizabeth A

2018-03-08

Herbaria are an invaluable source of plant material that can be used in a variety of biological studies. The use of herbarium specimens is associated with a number of challenges including sample preservation quality, degraded DNA, and destructive sampling of rare specimens. In order to more effectively use herbarium material in large sequencing projects, a dependable and scalable method of DNA isolation and library preparation is needed. This paper demonstrates a robust, beginning-to-end protocol for DNA isolation and high-throughput library construction from herbarium specimens that does not require modification for individual samples. This protocol is tailored for low quality dried plant material and takes advantage of existing methods by optimizing tissue grinding, modifying library size selection, and introducing an optional reamplification step for low yield libraries. Reamplification of low yield DNA libraries can rescue samples derived from irreplaceable and potentially valuable herbarium specimens, negating the need for additional destructive sampling and without introducing discernible sequencing bias for common phylogenetic applications. The protocol has been tested on hundreds of grass species, but is expected to be adaptable for use in other plant lineages after verification. This protocol can be limited by extremely degraded DNA, where fragments do not exist in the desired size range, and by secondary metabolites present in some plant material that inhibit clean DNA isolation. Overall, this protocol introduces a fast and comprehensive method that allows for DNA isolation and library preparation of 24 samples in less than 13 h, with only 8 h of active hands-on time with minimal modifications.

Control of tracers, fluids, and materials for the Yucca Mountain Site Characterization Project

International Nuclear Information System (INIS)

Kalia, H.N.

1993-01-01

This paper describes use and control of tracers, fluids, and materials (TFM) at the Yucca Mountain Site Characterization Project, Management of TFM is necessary to ensure that site characterization activity does not introduce TFM that may have impact on Yucca Mountain's ability to isolate high-level radioactive waste from the accessible environment. All participants must identify TFM used for testing and construction and have the TFM evaluated to ascertain any impact on waste isolation capabilities of the site or on adjacent tests. Two data bases are created to track TFM: a working data base managed by Los Alamos National Lab. and a permanent data base managed by EG ampersand G, which will contain information on actual TFM used

Pickering irradiated fuel transfer conveyor isolation

Energy Technology Data Exchange (ETDEWEB)

Koivisto, D J; Eijsermans, L J [Atomic Energy of Canada Ltd., Mississauga, ON (Canada)

1997-12-31

Pickering A NGS has been in operation for 25 years and is one of the longest in service CANDU stations. Some underwater fuel handling equipment, notably the conveyor stops, have been without maintenance throughout that time. This paper describes the concept of a conveyor isolation system that permits draining of a single or multiple elevator columns and also the early stages of a development program for the elastomeric sealing element. The prototype seal element has been proven in lab tests to be capable of limiting leakage to 0.5 IGPM (imperial gallons per minute) at the design pressure of 6.5 psi. The design of a sealing element is particularly interesting because the conveyor tube is a square cross-section which contains an additional obstruction , a conveyor drive cable. A seal delivery, actuating and positioning system has been conceptually laid out and the design is proceeding, with projected implementation in 1998. (author). 8 figs.

Pickering irradiated fuel transfer conveyor isolation

International Nuclear Information System (INIS)

Koivisto, D.J.; Eijsermans, L.J.

1996-01-01

Pickering A NGS has been in operation for 25 years and is one of the longest in service CANDU stations. Some underwater fuel handling equipment, notably the conveyor stops, have been without maintenance throughout that time. This paper describes the concept of a conveyor isolation system that permits draining of a single or multiple elevator columns and also the early stages of a development program for the elastomeric sealing element. The prototype seal element has been proven in lab tests to be capable of limiting leakage to 0.5 IGPM (imperial gallons per minute) at the design pressure of 6.5 psi. The design of a sealing element is particularly interesting because the conveyor tube is a square cross-section which contains an additional obstruction , a conveyor drive cable. A seal delivery, actuating and positioning system has been conceptually laid out and the design is proceeding, with projected implementation in 1998. (author). 8 figs

Isolation and Characterization of Pollulan Produced by a Local Isolate of Aureobasidium Pullulans

OpenAIRE

Kassim, Mohammad Bashir Ismail [محمد بشيراسماعيل قاسم

2000-01-01

A local isolate of Aureobasidium pullulans was obtained from fig leaves surface. The isolate was identified as A. pullulans on the basis of appearance of polymorphism in the colonies, melanin pigment and pullulan production in shake flask cultures. Pullulan production by the local isolate of A pullulans was two thirds of that produced by ATCC 42023. The studies of physico — chemical properties, chemical analysis, sugar composition periodate oxidation and smith degradation showed that the pull...

Recent advances in micro-vibration isolation

Science.gov (United States)

Liu, Chunchuan; Jing, Xingjian; Daley, Steve; Li, Fengming

2015-05-01

Micro-vibration caused by disturbance sources onboard spacecraft can severely degrade the working environment of sensitive payloads. Some notable vibration control methods have been developed particularly for the suppression or isolation of micro-vibration over recent decades. Usually, passive isolation techniques are deployed in aerospace engineering. Active isolators, however, are often proposed to deal with the low frequency vibration that is common in spacecraft. Active/passive hybrid isolation has also been effectively used in some spacecraft structures for a number of years. In semi-active isolation systems, the inherent structural performance can be adjusted to deal with variation in the aerospace environment. This latter approach is potentially one of the most practical isolation techniques for micro-vibration isolation tasks. Some emerging advanced vibration isolation methods that exploit the benefits of nonlinearity have also been reported in the literature. This represents an interesting and highly promising approach for solving some challenging problems in the area. This paper serves as a state-of-the-art review of the vibration isolation theory and/or methods which were developed, mainly over the last decade, specifically for or potentially could be used for, micro-vibration control.

Optimizing charge breeding techniques for ISOL facilities in Europe: Conclusions from the EMILIE project

Energy Technology Data Exchange (ETDEWEB)

Delahaye, P., E-mail: delahaye@ganil.fr; Jardin, P.; Maunoury, L. [GANIL, CEA/DSM-CNRS/IN2P3, Blvd. Becquerel, BP 55027, 14076 Caen Cedex 05 (France); Galatà, A.; Patti, G. [INFN–Laboratori Nazionali di Legnaro, Viale dell’Università 2, 35020 Legnaro (Padova) (Italy); Angot, J.; Lamy, T.; Thuillier, T. [LPSC–Université Grenoble Alpes–CNRS/IN2P3, 53 rue des Martyrs, 38026 Grenoble Cedex (France); Cam, J. F.; Traykov, E.; Ban, G. [LPC Caen, 6 Blvd. Maréchal Juin, 14050 Caen Cedex (France); Celona, L. [INFN–Laboratori Nazionali del Sud, via S. Sofia 62, 95125 Catania (Italy); Choinski, J.; Gmaj, P. [Heavy Ion Laboratory, University of Warsaw, ul. Pasteura 5a, 02 093 Warsaw (Poland); Koivisto, H.; Kolhinen, V.; Tarvainen, O. [Department of Physics, University of Jyväskylä, PB 35 (YFL), 40351 Jyväskylä (Finland); Vondrasek, R. [Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, Illinois 60439 (United States); Wenander, F. [ISOLDE, CERN, 1211 Geneva 23 (Switzerland)

2016-02-15

The present paper summarizes the results obtained from the past few years in the framework of the Enhanced Multi-Ionization of short-Lived Isotopes for Eurisol (EMILIE) project. The EMILIE project aims at improving the charge breeding techniques with both Electron Cyclotron Resonance Ion Sources (ECRIS) and Electron Beam Ion Sources (EBISs) for European Radioactive Ion Beam (RIB) facilities. Within EMILIE, an original technique for debunching the beam from EBIS charge breeders is being developed, for making an optimal use of the capabilities of CW post-accelerators of the future facilities. Such a debunching technique should eventually resolve duty cycle and time structure issues which presently complicate the data-acquisition of experiments. The results of the first tests of this technique are reported here. In comparison with charge breeding with an EBIS, the ECRIS technique had lower performance in efficiency and attainable charge state for metallic ion beams and also suffered from issues related to beam contamination. In recent years, improvements have been made which significantly reduce the differences between the two techniques, making ECRIS charge breeding more attractive especially for CW machines producing intense beams. Upgraded versions of the Phoenix charge breeder, originally developed by LPSC, will be used at SPES and GANIL/SPIRAL. These two charge breeders have benefited from studies undertaken within EMILIE, which are also briefly summarized here.

The plant functional traits that explain species occurrence across fragmented grasslands differ according to patch management, isolation, and wetness

Czech Academy of Sciences Publication Activity Database

Janečková, Petra; Janeček, Štěpán; Klimešová, Jitka; Götzenberger, Lars; Horník, J.; Lepš, J.; de Bello, Francesco

2017-01-01

Roč. 32, č. 4 (2017), s. 791-805 ISSN 0921-2973 R&D Projects: GA ČR GAP505/12/1296; GA ČR(CZ) GA16-12243S Institutional support: RVO:67985939 Keywords : Functional traits * Isolation * Management Subject RIV: EH - Ecology, Behaviour OBOR OECD: Ecology Impact factor: 3.615, year: 2016

Patients experience of source isolation

DEFF Research Database (Denmark)

Johansen, Kamilla; Pedersen, Didde; Kragbak, Nina

2014-01-01

, Nursing education in Århus, Hedeager 2, 8200 Aarhus N, Denmark. Background: Medical treatment and care of patients with infections may include source isolation of the patient, to avoid spreading of the infection. However, isolation is a potential physiological and psychological stress factor...... of the patients perspectives of being isolated to identify areas of potential interest for developing new caring strategies to minimize the negative side effects of isolation. Methods: Literature was systematically searched in CINAHL, Nursing Reference Center, Social Care Online, SveMed+, The Cochrane Library...... of Care: The patients felt abandoned and forgotten by the nurses, because of fewer visits and time limited communication. This led to emotions such as frustrations, insecurity and neglect. While isolated the patients felt it difficult to achieve contact and have an optimal relation with the nurses...

Status of U.S. Plans for an Advanced ISOL Facility. A Brief Report

International Nuclear Information System (INIS)

Bertrand, F.E.

1998-01-01

A brief discussion is provided of the current status of plans to build an advanced ISOL radioactive ion beam facility in the US. Designs for this new facility, which was recommended as the next major construction project of the DOE Nuclear Physics Program Office, have been proposed by two US national laboratories, Argonne National Laboratory and Oak Ridge National Laboratory. The new facility will provide orders-of-magnitude higher radioactive beam currents than existing facilities of this type and will cost in the range of $250 million

Project experimental house in Caceres; Proyecto vivienda experimental en Caceres

Energy Technology Data Exchange (ETDEWEB)

Gamero, E.; Mendez, L.

2008-07-01

The project envisages to develop and efficient methodology for the design and building of social housing in the region of Extremadura, with the aim to obtaining sustainable buildings, with a better energy behaviour, and the use of renewable energy sources, in addition to ensuring a substantial increase of the quality of construction. the project is based on the construction of two isolated houses which will have the same geographical orientation and equal structural system, so they both will be subject to the same climate conditions. One of the houses (pattern house) will be built following exactly the construction being used for the Special Housing Plan, whilst the second on (Experimental house) will serve as a laboratory where to test and demonstrate different sustainability measures and renewable energy sources. (Author)

Radioactive waste disposal: Waste isolation pilot plants (WIPP). (Latest citations from the NTIS Bibliographic database). Published Search

International Nuclear Information System (INIS)

1993-09-01

The bibliography contains citations concerning the Waste Isolation Pilot Plant (WIPP), a geologic repository located in New Mexico for transuranic wastes generated by the U.S. Government. Articles follow the development of the program from initial site selection and characterization through construction and testing, and examine research programs on environmental impacts, structural design, and radionuclide landfill gases. Existing plants and facilities, pilot plants, migration, rock mechanics, economics, regulations, and transport of wastes to the site are also included. The Salt Repository Project and the Crystalline Repository Project are referenced in separate bibliographies. (Contains a minimum of 228 citations and includes a subject term index and title list.)

Displacement of diesel fuel with wind energy in rural Alaskan villages. Final progress and project closeout report

Energy Technology Data Exchange (ETDEWEB)

Meiners, Dennis [Alaska Industrial Development and Export Authority, Anchorage, AK (United States); Drouhilet, Steve [National Renewable Energy Lab. (NREL), Golden, CO (United States); Reeve, Brad [Alaska Industrial Development and Export Authority, Anchorage, AK (United States); Bergen, Matt [Kotzebue Electric Association, Kotzebue, AK (United States)

2002-03-11

The basic concept behind this project was to construct a wind diesel hybrid power system which combines and maximizes the intermittent and variable energy output of wind turbine(s) with diesel generator(s) to provide continuous high quality electric power to weak isolated mini-grids.

Seismic isolation of nuclear power plants using sliding isolation bearings

Science.gov (United States)

Kumar, Manish

Nuclear power plants (NPP) are designed for earthquake shaking with very long return periods. Seismic isolation is a viable strategy to protect NPPs from extreme earthquake shaking because it filters a significant fraction of earthquake input energy. This study addresses the seismic isolation of NPPs using sliding bearings, with a focus on the single concave Friction Pendulum(TM) (FP) bearing. Friction at the sliding surface of an FP bearing changes continuously during an earthquake as a function of sliding velocity, axial pressure and temperature at the sliding surface. The temperature at the sliding surface, in turn, is a function of the histories of coefficient of friction, sliding velocity and axial pressure, and the travel path of the slider. A simple model to describe the complex interdependence of the coefficient of friction, axial pressure, sliding velocity and temperature at the sliding surface is proposed, and then verified and validated. Seismic hazard for a seismically isolated nuclear power plant is defined in the United States using a uniform hazard response spectrum (UHRS) at mean annual frequencies of exceedance (MAFE) of 10-4 and 10 -5. A key design parameter is the clearance to the hard stop (CHS), which is influenced substantially by the definition of the seismic hazard. Four alternate representations of seismic hazard are studied, which incorporate different variabilities and uncertainties. Response-history analyses performed on single FP-bearing isolation systems using ground motions consistent with the four representations at the two shaking levels indicate that the CHS is influenced primarily by whether the observed difference between the two horizontal components of ground motions in a given set is accounted for. The UHRS at the MAFE of 10-4 is increased by a design factor (≥ 1) for conventional (fixed base) nuclear structure to achieve a target annual frequency of unacceptable performance. Risk oriented calculations are performed for

Improved hybrid isolator with maglev actuator integrated in air spring for active-passive isolation of ship machinery vibration

Science.gov (United States)

Li, Yan; He, Lin; Shuai, Chang-geng; Wang, Chun-yu

2017-10-01

A hybrid isolator consisting of maglev actuator and air spring is proposed and developed for application in active-passive vibration isolation system of ship machinery. The dynamic characteristics of this hybrid isolator are analyzed and tested. The stability and adaptability of this hybrid isolator to shock and swing in the marine environment are improved by a compliant gap protection technique and a disengageable suspended structure. The functions of these new engineering designs are proved by analytical verification and experimental validation of the designed stiffness of such a hybrid isolator, and also by shock adaptability testing of the hybrid isolator. Finally, such hybrid isolators are installed in an engineering mounting loaded with a 200-kW ship diesel generator, and the broadband and low-frequency sinusoidal isolation performance is tested.

The Search for Violacein-Producing Microbes to Combat Batrachochytrium dendrobatidis: A Collaborative Research Project between Secondary School and College Research Students

Directory of Open Access Journals (Sweden)

Larra Agate

2015-10-01

Full Text Available In this citizen science–aided, college laboratory–based microbiology research project, secondary school students collaborate with college research students on an investigation centered around bacterial species in the local watershed. This study specifically investigated the prevalence of violacein-producing bacterial isolates, as violacein has been demonstrated as a potential bioremediation treatment for outbreaks of the worldwide invasive chytrid, Batrachochytrium dendrobatidis (Bd. The impact of this invasion has been linked to widespread amphibian decline, and tracking of the spread of Bd is currently ongoing. Secondary school students participated in this research project by sterilely collecting water samples from a local watershed, documenting the samples, and completing the initial sample plating in a BSL1 environment. In the second phase of this project, trained college students working in courses and as research assistants in the academic year and summer term in a BSL2 laboratory facility were able to use physiological, biochemical, and molecular techniques to further identify individual isolates as well as characterize their properties. Collaboration between these learning spaces provides an increased interest in the community for environmentally relevant research projects and allows for an expansion of the research team to increase study robustness.

Implementation of NUREG-1318 guidance within the Yucca Mountain Project

International Nuclear Information System (INIS)

La Monica, L.B.; Waddell, J.D.; Hardin, E.L.

1990-01-01

The US Department of Energy's Yucca Mountain Project is implementing a quality assurance program that fulfills the requirements of the US Nuclear Regulatory Commission (NRC). Additional guidance for this program was provided in NUREG 1318, ''Technical Position on Items and Activities in the High-Level Waste Geologic Repository Program Subject to Quality Assurance Requirements'' for identification of items and activities important to public radiological safety and waste isolation. The process and organization for implementing this guidance is discussed. 3 refs., 2 figs

Final report on Paradox Basin/Gulf Interior: Regulatory project management

International Nuclear Information System (INIS)

1986-12-01

This final report on the Regulatory Project Manager (RPM) program begins with a discussion of the key products produced during the 9-year effort and then focuses on the work performed in the major disciplines. The report then discusses the management of the work effort and the Quality Assurance (QA) program. It concludes with a brief discussion of the records turned over to the Office of Nuclear Waste Isolation (ONWI) at the conclusion of the work. 14 figs., 14 tabs

Projecting the range of potential future climate change as an aid in the assessment of the effectiveness of the Hanford Site Permanent Isolation Barrier

Energy Technology Data Exchange (ETDEWEB)

Petersen, K.L.

1993-10-01

The Hanford Site Permanent Isolation Barrier Development Program was organized to develop an in-place disposal capability for low-level nuclear waste for the US Department of Energy at the Hanford Site in south-eastern Washington. Layered earthen and engineered barriers are being developed by Westinghouse Hanford Company and the Pacific Northwest Laboratory that will function in what is presently a semiarid environment (annual precipitation 150 mm) for at least 1,000 yr by limiting the infiltration of water through the waste. The Long-Term Climate Change Task is one of several key barrier tasks. Based on the recommendation of a panel of internationally recognized climate and modeling experts, climatic data for this task is being acquired in a step-wise and multi-disciplinary manner. The specific research strategy includes literature review and specialized studies to obtain pollen-derived climatic reconstruction, documented historic weather patterns, and Global Circulation Model output of potential future climate changes related to both the greenhouse effect and the cycling into the next ice age. The specific goals of the task are to: (1) obtain defensible probabilistic projections of the long-term climate variability in the Hanford Site region at many different time scales into the future, (2) develop several test case climate scenarios that bracket the range of potential future climate, and (3) use the climate scenarios both to test and to model protective barrier performance.

Project FIND: a profile of a community-based senior services agency.

Science.gov (United States)

Lockwood, Andrée

2007-01-01

Project FIND has been providing innovative supportive housing, nutrition, and social support to homeless and low- and moderate-income seniors on New York City's West Side since 1967. This article profiles this nonprofit, community-based agency, which was established to meet the needs of the frail and isolated elderly, and has continued to grow and evolve in response to changing demographics, neighborhood gentrification, and needs of both the homeless as well as the active "younger old." The article describes creative programming that has distinguished Project FIND's response to seniors' needs beyond basic housing and nutrition. It also explores what it takes to successfully provide senior services using limited resources and examines challenges for the future both nationally and for the agency.

Isolation and in vitro evaluation of bacteriophages against MDR-bacterial isolates from septic wound infections.

Directory of Open Access Journals (Sweden)

Roja Rani Pallavali

Full Text Available Multi-drug resistance has become a major problem for the treatment of pathogenic bacterial infections. The use of bacteriophages is an attractive approach to overcome the problem of drug resistance in several pathogens that cause fatal diseases. Our study aimed to isolate multi drug resistant bacteria from patients with septic wounds and then isolate and apply bacteriophages in vitro as alternative therapeutic agents. Pus samples were aseptically collected from Rajiv Gandhi Institute of Medical Science (RIMS, Kadapa, A.P., and samples were analyzed by gram staining, evaluating morphological characteristics, and biochemical methods. MDR-bacterial strains were collected using the Kirby-Bauer disk diffusion method against a variety of antibiotics. Bacteriophages were collected and tested in vitro for lytic activity against MDR-bacterial isolates. Analysis of the pus swab samples revealed that the most of the isolates detected had Pseudomonas aeruginosa as the predominant bacterium, followed by Staphylococcus aureus, Klebsiella pneumoniae and Escherichia coli. Our results suggested that gram-negative bacteria were more predominant than gram-positive bacteria in septic wounds; most of these isolates were resistant to ampicillin, amoxicillin, penicillin, vancomycin and tetracycline. All the gram-positive isolates (100% were multi-drug resistant, whereas 86% of the gram-negative isolates had a drug resistant nature. Further bacteriophages isolated from sewage demonstrated perfect lytic activity against the multi-drug resistant bacteria causing septic wounds. In vitro analysis of the isolated bacteriophages demonstrated perfect lysis against the corresponding MDR-bacteria, and these isolated phages may be promising as a first choice for prophylaxis against wound sepsis, Moreover, phage therapy does not enhance multi-drug resistance in bacteria and could work simultaneously on a wide variety of MDR-bacteria when used in a bacteriophage cocktail. Hence

Variable stiffness and damping MR isolator

Energy Technology Data Exchange (ETDEWEB)

Zhang, X Z; Wang, X Y; Li, W H; Kostidis, K [University of Wollongong, School of Mechanical, Materials and Mechatronic Engineering, NSW 2522 (Australia)], E-mail: weihuali@uow.edu.au

2009-02-01

This paper presents the development of a magnetorheological (MR) fluid-based variable stiffness and damping isolator for vibration suppressions. The MR fluid isolator used a sole MR control unit to achieve the variable stiffness and damping in stepless and relative large scope. A mathematical model of the isolator was derived, and a prototype of the MR fluid isolator was fabricated and its dynamic behavior was measured in vibration under various applied magnetic fields. The parameters of the model under various magnetic fields were identified and the dynamic performances of isolator were evaluated.

A preliminary social and economic assessment of the Basalt Waste Isolation Project

International Nuclear Information System (INIS)

Cluett, C.; Bolton, P.; York, K.; Wood, M.; Radford, L.

1981-07-01

This report provides a preliminary assessment of the social and economic impacts that could be caused by the construction and operation of a nuclear waste repository on the Hanford Site near Richland, Washington. This assessment involved assembling a comprehensive data base for the local Tri-Cities impact area and the surrounding region, establishing a network of local and regional contacts, making preliminary judgments about potential social impacts caused by the proposed repository, and recommending further research. This report concludes that growth effects under the anticipated work force scenario are expected to be relatively minor. With a strong public involvement program on the part of the project developers, including an ongoing dialogue with local and regional planners, potential socio-economic impacts can be anticipated and managed effectively. Specific recommendations are made for filling gaps in the available data, exploring key issues in more detail, and improving the analysis of social impacts. The report was prepared by the Battelle-Human Affairs Research Center in 1980 and 1981

Molecular Phylogenetic Classification of Streptomycetes Isolated from the Rhizosphere of Tropical Legume (Paraserianthes falcataria (L. Nielsen

Directory of Open Access Journals (Sweden)

LANGKAH SEMBIRING

2009-09-01

Full Text Available Intrageneric diversity of 556 streptomycetes isolated from the rhizosphere of tropical legume was determined by using molecular taxonomic method based on 16S rDNA. A total of 46 isolates were taken to represent 37 colour groups of the isolates. 16S rDNA were amplified and subsequently sequenced and the sequences data were aligned with streptomycete sequences retrieved from the ribosomal data base project (RDP data. Phylogenetic trees were generated by using the PHYLIP software package and the matrix of nucleotide similarity and nucleotide difference were generated by using PHYDIT software. The results confirmed and extended the value of 16S rDNA sequencing in streptomycete systematic. The 16S rDNA sequence data showed that most of the tested colour group representatives formed new centers of taxonomic variation within the genus Streptomyces. The generic assignment of these organisms was underpinned by 16S rDNA sequence data which also suggested that most of the strains represented new centers of taxonomic variation. The taxonomic data indicate that diverse populations of streptomycetes are associated with the roots of tropical legume (P. falcataria. Therefore, the combination of selective isolation and molecular taxonomic procedures used in this study provide a powerful way of uncovering new centers of taxonomic variation within the genus Streptomyces.

Chitinolytic enzymes from bacterium inhabiting human gastrointestinal tract - critical parameters of protein isolation from anaerobic culture

Czech Academy of Sciences Publication Activity Database

Dušková, Jarmila; Tishchenko, Galina; Ponomareva, E.; Šimůnek, Jiří; Koppová, Ingrid; Skálová, Tereza; Štěpánková, Andrea; Hašek, Jindřich; Dohnálek, Jan

2011-01-01

Roč. 58, č. 2 (2011), s. 261-263 ISSN 0001-527X R&D Projects: GA ČR GA310/09/1407; GA ČR GA305/07/1073 Institutional research plan: CEZ:AV0Z40500505; CEZ:AV0Z50450515 Keywords : chitinolytic enzymes * anaerobic cultivation * protein isolation Subject RIV: EE - Microbiology, Virology Impact factor: 1.491, year: 2011 http://www.actabp.pl/pdf/2_2011/261.pdf

Los Alamos National Laboratory TRU waste sampling projects

International Nuclear Information System (INIS)

Yeamans, D.; Rogers, P.; Mroz, E.

1997-01-01

The Los Alamos National Laboratory (LANL) has begun characterizing transuranic (TRU) waste in order to comply with New Mexico regulations, and to prepare the waste for shipment and disposal at the Waste Isolation Pilot Plant (WIPP), near Carlsbad, New Mexico. Sampling consists of removing some head space gas from each drum, removing a core from a few drums of each homogeneous waste stream, and visually characterizing a few drums from each heterogeneous waste stream. The gases are analyzed by GC/MS, and the cores are analyzed for VOC's and SVOC's by GC/MS and for metals by AA or AE spectroscopy. The sampling and examination projects are conducted in accordance with the ''DOE TRU Waste Quality Assurance Program Plan'' (QAPP) and the ''LANL TRU Waste Quality Assurance Project Plan,'' (QAPjP), guaranteeing that the data meet the needs of both the Carlsbad Area Office (CAO) of DOE and the ''WIPP Waste Acceptance Criteria, Rev. 5,'' (WAC)

Project of an integrated calibration laboratory of instruments at IPEN; Projeto de um laboratorio integrado de calibracao de instrumentos no IPEN

Energy Technology Data Exchange (ETDEWEB)

Barros, Gustavo Adolfo San Jose

2009-07-01

The Calibration Laboratory of Instruments of Instituto de Pesquisas Energeticas e Nucleares offers calibration services of radiation detectors used in radioprotection, diagnostic radiology and radiotherapy, for IPEN and for external facilities (public and private). One part of its facilities is located in the main building, along with other laboratories and study rooms, and another part in an isolated building called Bunker. For the optimization, modernization and specially the safety, the laboratories in the main building shall be transferred to an isolated place. In this work, a project of an integrated laboratory for calibration of instruments was developed, and it will be an expansion of the current Calibration Laboratory of Instruments of IPEN. Therefore, a series of radiometric monitoring of the chosen localization of the future laboratory was realized, and all staff needs (dimensions and disposition of the study rooms and laboratories) were defined. In this project, the laboratories with X ray equipment, alpha and beta radiation sources were located at an isolated part of the building, and the wall shielding was determined, depending on the use of each laboratory. (author)

Groundwater monitoring at the Waste Isolation Pilot Plant

International Nuclear Information System (INIS)

Kehrman, R.; Broberg, K.; Tatro, G.; Richardson, R.; Dasczcyszak, W.

1990-01-01

This paper discusses the Groundwater Monitoring Program (GPM) being conducted at the Waste Isolation Pilot Plant (WIPP) in Carlsbad, New Mexico. The Regulatory and Environmental Programs (REP) section of the Environment, Safety and Health department (ES ampersand H) is responsible for conducting environmental monitoring at the WIPP. Groundwater monitoring is one of the ongoing environmental activities currently taking place. The REP section includes water quality sampling and water level monitoring. The WIPP Project is a research and develop facility designed to demonstrate the safe disposal of defense-generated waste in a geologic repository. Water quality sampling for physical, chemical, and radiological parameters has been an ongoing activity at the WIPP site for the past six years, and will continue through the life of the project. The water quality of a well is sampled while the well is continuously pumped. Serial samples of the pumped water are collected and tested for pH, Eh, temperature, specific gravity, specific conductivity, alkalinity, chlorides, divalent cations, ferrous iron, and total iron. Stabilization of serial sampling parameters determined if a representative sample is being obtained, Representative samples are sent to contract laboratories and analyzed for general chemistry, major cations and anions, and radionuclides. 13 refs., 4 figs., 1 tab

Frequency of isolation and antibiotic resistance patterns of bacterial isolates from wound infections

Directory of Open Access Journals (Sweden)

Stojanović-Radić, Z.

2016-12-01

Full Text Available Six hundred and thirteen bacterial strains were isolated from wound swabs and the isolates were identified on the basis of growth on differential and selective media. In order to test the sensitivity of isolated strains to different antibiotics, the disc diffusion method, according to EUCAST protocol v 5.0 was used. The most common species isolated from wound swabs was Staphylococcus epidermidis (18.4%, followed by Staphylococcus aureus, Pseudomonas aeruginosa and Enterococcus faecalis (16.8%, 12.7% and 10.4%, respectively. The maximum resistance of Gram-positive cocci was observed to penicillin and the lowest to linezolid. Gram-negative bacteria showed the highest resistance to tetracyclines, while the same strains demonstrated the highest sensitivity to polypeptide antibiotics. Comparison of the resistance patterns of Gramnegative and Gram-positive bacterial strains showed significant difference in the tetracycline efficiency.

Comparison of seismic isolation concepts for FBR

International Nuclear Information System (INIS)

Shiojiri, H.; Mazda, T.; Kasai, H.; Kanda, J.N.; Kubo, T.; Madokoro, M.; Shimomura, T.; Nojima, O.

1989-01-01

This paper seeks to verify the reliability and effectiveness of seismic isolation for FBR. Some results of the preliminary study of the program are described. Seismic isolation concepts and corresponding seismic isolation devices were selected. Three kinds of seismically-isolated FBR plant concepts were developed by applying promising seismic isolation concepts to the non-isolated FBR plant, and by developing plant component layout plans and building structural designs. Each plant was subjected to seismic response analysis and reduction in the amount of material of components and buildings were estimated for each seismic isolation concepts. Research and development items were evaluated

Risk analysis for renewable energy projects due to constraints arising

Science.gov (United States)

Prostean, G.; Vasar, C.; Prostean, O.; Vartosu, A.

2016-02-01

Starting from the target of the European Union (EU) to use renewable energy in the area that aims a binding target of 20% renewable energy in final energy consumption by 2020, this article illustrates the identification of risks for implementation of wind energy projects in Romania, which could lead to complex technical implications, social and administrative. In specific projects analyzed in this paper were identified critical bottlenecks in the future wind power supply chain and reasonable time periods that may arise. Renewable energy technologies have to face a number of constraints that delayed scaling-up their production process, their transport process, the equipment reliability, etc. so implementing these types of projects requiring complex specialized team, the coordination of which also involve specific risks. The research team applied an analytical risk approach to identify major risks encountered within a wind farm project developed in Romania in isolated regions with different particularities, configured for different geographical areas (hill and mountain locations in Romania). Identification of major risks was based on the conceptual model set up for the entire project implementation process. Throughout this conceptual model there were identified specific constraints of such process. Integration risks were examined by an empirical study based on the method HAZOP (Hazard and Operability). The discussion describes the analysis of our results implementation context of renewable energy projects in Romania and creates a framework for assessing energy supply to any entity from renewable sources.

DISCOVERY OF A WIDE BINARY BROWN DWARF BORN IN ISOLATION

International Nuclear Information System (INIS)

Luhman, K. L.; Allen, P. R.; Mamajek, E. E.; Muench, A. A.; Finkbeiner, D. P.

2009-01-01

During a survey for stars with disks in the Taurus star-forming region using the Spitzer Space Telescope, we have discovered a pair of young brown dwarfs, FU Tau A and B, in the Barnard 215 dark cloud. They have a projected angular separation of 5.''7, corresponding to 800 AU at the distance of Taurus. To assess the nature of these two objects, we have obtained spectra of them and constructed spectral energy distributions. Both sources are young (∼1 Myr) according to their Hα emission, gravity-sensitive spectral features, and mid-infrared excess emission. The proper motion of FU Tau A provides additional evidence of its membership in Taurus. We measure spectral types of M7.25 and M9.25 for FU Tau A and B, respectively, which correspond to masses of ∼0.05 and ∼0.015 M sun according to the evolutionary models of Chabrier and Baraffe. FU Tau A is significantly overluminous relative to an isochrone passing through FU Tau B and relative to other members of Taurus near its spectral type, which may indicate that it is an unresolved binary. FU Tau A and B are likely to be components of a binary system based on the low probability (∼3 x 10 -4 ) that Taurus would produce two unrelated brown dwarfs with a projected separation of a ≤ 6''. Barnard 215 contains only one other young star and is in a remote area of Taurus, making FU Tau A and B the first spectroscopically confirmed brown dwarfs discovered forming in isolation rather than in a stellar cluster or aggregate. Because they were born in isolation and comprise a weakly bound binary, dynamical interactions with stars could not have played a role in their formation, and thus are not essential for the birth of brown dwarfs.

Teaching basic lung isolation skills on human anatomy simulator: attainment and retention of lung isolation skills.

Science.gov (United States)

Latif, Rana K; VanHorne, Edgar M; Kandadai, Sunitha Kanchi; Bautista, Alexander F; Neamtu, Aurel; Wadhwa, Anupama; Carter, Mary B; Ziegler, Craig H; Memon, Mohammed Faisal; Akça, Ozan

2016-01-20

Lung isolation skills, such as correct insertion of double lumen endobronchial tube and bronchial blocker, are essential in anesthesia training; however, how to teach novices these skills is underexplored. Our aims were to determine (1) if novices can be trained to a basic proficiency level of lung isolation skills, (2) whether video-didactic and simulation-based trainings are comparable in teaching lung isolation basic skills, and (3) whether novice learners' lung isolation skills decay over time without practice. First, five board certified anesthesiologist with experience of more than 100 successful lung isolations were tested on Human Airway Anatomy Simulator (HAAS) to establish Expert proficiency skill level. Thirty senior medical students, who were naive to bronchoscopy and lung isolation techniques (Novice) were randomized to video-didactic and simulation-based trainings to learn lung isolation skills. Before and after training, Novices' performances were scored for correct placement using pass/fail scoring and a 5-point Global Rating Scale (GRS); and time of insertion was recorded. Fourteen novices were retested 2 months later to assess skill decay. Experts' and novices' double lumen endobronchial tube and bronchial blocker passing rates showed similar success rates after training (P >0.99). There were no differences between the video-didactic and simulation-based methods. Novices' time of insertion decayed within 2 months without practice. Novices could be trained to basic skill proficiency level of lung isolation. Video-didactic and simulation-based methods we utilized were found equally successful in training novices for lung isolation skills. Acquired skills partially decayed without practice.

MOX Fabrication Isolation Considerations

Energy Technology Data Exchange (ETDEWEB)

Eric L. Shaber; Bradley J Schrader

2005-08-01

This document provides a technical position on the preferred level of isolation to fabricate demonstration quantities of mixed oxide transmutation fuels. The Advanced Fuel Cycle Initiative should design and construct automated glovebox fabrication lines for this purpose. This level of isolation adequately protects the health and safety of workers and the general public for all mixed oxide (and other transmutation fuel) manufacturing efforts while retaining flexibility, allowing parallel development and setup, and minimizing capital expense. The basis regulations, issues, and advantages/disadvantages of five potential forms of isolation are summarized here as justification for selection of the preferred technical position.

Isolation and identification of citrus psorosis virus Egyptian isolate (CPsV-EG).

Science.gov (United States)

Ghazal, S A; El-Dougdoug, Kh A; Mousa, A A; Fahmy, H; Sofy, A R

2008-01-01

Citrus psorosis ophiovirus (CPsV), is considered to be of the most serious and deter mental virus pathogen's citrus species trees in Egypt. CPsV-EG was isolated from infected citrus grapefruit (C. paradisi Macf.) at Agric. Res. Centre (ARC). The grapefruit which used for CPsV-EG isolate was found to be free from CTV, CEVd and Spiroplasma citri where as gave -ve results with DTBIA, tissue print hybridization and Diene's stain respectively. CPsV-EG was detected on the basis of biological indexing by graft inoculation which gave oak leaf pattern (OLP) on Dweet tangor and serological assay by DAS-ELISA using Mab specific CPsV. CPsV-EG was reacted with variable responses on 16 host plants belonging to 6 families. Only 8 host plants are susceptible and showed visible external symptoms which appeared as local, systemic and local followed by systemic infections. CPsV-EG isolate was transmitted from infected citrus to citrus by syringe and grafting and herbaceous plants by forefinger inoculation and syringe. The woody indicators and rootstocks were differed in response to CPsV-EG isolate which appeared as no-response, response, sensitivity and hypersensitivity. The serological characters represented as the antigenic determinants of CPsV-EG isolate related to monoclonal antibodies specific CPsV strain where as appeared precipitation reaction by DAS-ELISA and DTBIA. The partial fragment of RNA3 (coat protein gene) of CPsV-EG (-1140bp and -571bp) was amplified by reverse transcription-polymerase chain reaction (RT-PCR) from grapefruit tissues using two sets primers specific CPsV (CPV3 and CPV4) and (PS66 and PS65) respectively. The virus under study was identified as CPsV-EG isolate according to biological, serological and molecular characters.

STRATEGY AND PLANNING - PROJECT FOR MONITORING STRICTO SENSU POSTGRADUATE ALUMNI

Directory of Open Access Journals (Sweden)

Emerson Antonio Maccari

2014-07-01

Full Text Available The Coordination of Improvement of Higher Education Personnel (CAPES has been contributing to the development of post-graduate studies in Brazil, through its system of evaluation. Lately, CAPES signaled the importance of follow the professional performance of the alumni as a way to measure the quality of courses. One difficulty reported by institutions that intend to recognize the trajectory of its graduates is to compile a lot of isolated and outdated data. In order to structure the data collection and to assist educational managers in decision making, we propose the development of a system that enables the evolution of the students and alumni professional career, in order to diagnose the influence of the courses. Based on literature review, this study presents an analysis and makes recommendations about the Monitoring Alumni Project planning. As a result, it is expected that the analysis will serve as a driver for conducting the project, aiming to contribute to the academic reflections, and in practice, contribute to improve educational projects quality.

Isolation rooms for highly infectious diseases: an inventory of capabilities in European countries

DEFF Research Database (Denmark)

Fusco, F M; Puro, V; Baka, A

2009-01-01

Isolation of patients with highly infectious diseases (HIDs) in hospital rooms with adequate technical facilities is essential to reduce the risk of spreading disease. The European Network for Infectious Diseases (EUNID), a project co-funded by European Commission and involving 16 European Union...... on prevailing circumstances. Sporadic HID cases can be managed in the available HIRs. HIRs could also have a role in the initial phases of an influenza pandemic. However, large outbreaks due to natural or to bioterrorist events will need management strategies involving healthcare facilities other than HIRs....

Isolation, characterization, virulence and immunogenicity testing of field isolates of Pasteurella multocida, Staphylococcus aureus, and Streptococcus agalactiae in laboratory settings.

Science.gov (United States)

Qudratullah; Muhammad, G; Saqib, M; Bilal, M Qamar

2017-08-01

The present study was designed to investigate isolation, characterization, virulence and immunogenicity testing of field isolates of Pasteurella multocida, Staphylococcus aureus, and Streptococcus agalactiae in rabbits and mice. Isolates of P. multocida, S. aureus and Str. agalactiae recovered from field cases of Hemorragic septicemia and mastitis were scrutinized for virulence/pathogenicity and immunogenicity. Mouse LD 50 of P. multocida showed that P. multocida isolate No.1 was more virulent than isolates No. 2 and 3. Virulence of isolate No.1S. aureus and Str. agalactiae revealed that 100, 80% rabbits died within 18h of inoculation. Seven-digit numerical profiles of these 4 isolates with API ® Staph test strips isolates, No.1 (6736153) showed good identification (S. aureus id=90.3%). Indirect ELISA-based serum antibody titers to P. multocida isolate No.1, S. aureus No.1, Str. agalactiae, isolate No.1 elicited high antibody titers 1.9, 1.23, 1.12 respectively. All the pathogens of Isolate No. 1 (P. multocida, S. aureus Str. agalactiae), were high antibody than others isolates. Copyright © 2017 Elsevier B.V. All rights reserved.

Isolation and antibiogram of Staphylococcus, Streptococcus and Escherichia coli isolates from clinical and subclinical cases of bovine mastitis

Directory of Open Access Journals (Sweden)

Nihar Nalini Mohanty,

2013-08-01

Full Text Available Aim: The present study was aimed to isolate and evaluate the continuous change in the pattern of drug resistance showed by different mastitogenic organisms, isolated from clinical and subclinical cases of mastitis.Materials and Methods: The study was carried out using 150 milk samples received from various clinical and subclinical cases, from which the causative organisms were isolated and subjected to in vitro antibiotic sensitivity test.Results: The bacteriological analysis of the samples indicated the presence of both Gram positive and Gram negative organisms followed by isolation of isolates like Staphylococcus, E. coli, Streptococcus, Bacillus, Corynebacterium, Listeria, Klebsiella. The in vitro sensitivity of Staphylococcus, E. coli and Streptococcus isolates revealed that they were more sensitive towards newer antimicrobials like Levofloxacin and Enrofloxacin.Conclusion: The prevalence of Staphylococcus was found to be maximum followed by Streptococcus and E. coli among the isolated organisms. Levofloxacin and Enrofloxacin were found to be most effective against the targeted isolates.

STRATEGIC MAPS AND CRITICAL FACTORS FOR PROJECT MANAGEMENT MATURITY: A PROPOSAL

Directory of Open Access Journals (Sweden)

Sady Darcy Silva Junior

2010-06-01

Full Text Available Project Management (PM and Strategic Management (SM are two subjects of growing importance in the corporate environment which are normally considered in isolation. One way of integrating these two concepts might be via the concept of project management maturity (Westphal et al., 2008. Rabechini and Pessoa (2005 state that to obtain project management maturity, it is necessary to achieve success in a number of critical factors which include organizational culture and structure, as well as sponsorship at both tactical and strategic levels (Silva et al., 2008. Another way of achieving this connection is by using Balanced Scorecard (BSC as an auxiliary tool to integrate between projects and organizational strategy (Brock et al., 2003. The original developers of the BSC, Kaplan e Norton, subsequently developed the concept of strategy mapping, which they affirm "represents the missing link between the formulation and the execution of the strategy" (Kaplan e Norton, 2004. This paper proposes a strategy map identifying critical factors for attaining project management maturity. To formulate the map, we used a qualitative, exploratory approach oriented by Project Management theory and strategy mapping. We first identified 13 critical factors, then developed a strategy map, which was evaluated by six specialists (three in SM area and three in PM area.The results suggest links between strategic mapping nad critical factors in project management. It also contributes to both areas independently. Specifically, the study identifies critical factors for project management maturity while demonstrating the applicability of strategic mapping techniques to Balanced Scorecard concepts.

CrossRef Optimizing charge breeding techniques for ISOL facilities in Europe: Conclusions from the EMILIE project

CERN Document Server

Delahaye, P; Angot, J; Cam, J F; Traykov, E; Ban, G; Celona, L; Choinski, J; Gmaj, P; Jardin, P; Koivisto, H; Kolhinen, V; Lamy, T; Maunoury, L; Patti, G; Thuillier, T; Tarvainen, O; Vondrasek, R; Wenander, F

2016-01-01

The present paper summarizes the results obtained from the past few years in the framework of the Enhanced Multi-Ionization of short-Lived Isotopes for Eurisol (EMILIE) project. The EMILIE project aims at improving the charge breeding techniques with both Electron Cyclotron Resonance Ion Sources (ECRIS) and Electron Beam Ion Sources (EBISs) for European Radioactive Ion Beam (RIB) facilities. Within EMILIE, an original technique for debunching the beam from EBIS charge breeders is being developed, for making an optimal use of the capabilities of CW post-accelerators of the future facilities. Such a debunching technique should eventually resolve duty cycle and time structure issues which presently complicate the data-acquisition of experiments. The results of the first tests of this technique are reported here. In comparison with charge breeding with an EBIS, the ECRIS technique had lower performance in efficiency and attainable charge state for metallic ion beams and also suffered from issues related to beam c...

Isolation and identification of bovine Brucella isolates from Pakistan by biochemical tests and PCR.

Science.gov (United States)

Ali, Shahzad; Ali, Qurban; Melzer, Falk; Khan, Iahtasham; Akhter, Shamim; Neubauer, Heinrich; Jamal, Syed M

2014-01-01

Brucellosis is endemic in bovines in Pakistan. The Brucella species and biovars involved, however, are unknown. The objectives of the present study were to isolate and characterize brucellae from seropositive milk samples, aborted fetuses, and vaginal swabs of cattle and buffaloes which had recently aborted. The seropositive milk samples, aborted fetuses, and vaginal swabs of cattle and buffaloes were collected from the Potohar Plateau, Pakistan. Isolation of brucellae was done on modified Farrell's serum dextrose agar. Isolates were characterized by conventional biotyping methods, while molecular typing was done by genus (B4/B5) and species-specific (Brucella abortus, Brucella melitensis, Brucella ovis, and Brucella suis) polymerase chain reaction (PCR). A total of 30 isolates were recovered from milk (n = 5), aborted fetuses (n = 13), and vaginal swabs (n = 12). Most isolates were from cattle (56.7 %). All of them were identified as B. abortus biovar 1 based on conventional biotyping methods and genus and species-specific PCR. This preliminary study provides the first report on the prevalence of B. abortus biovar 1 in cattle and buffaloes in Pakistan.

Isolation, Identification, and Evaluation of Novel Probiotic Strains Isolated from Feces of Breast-Fed Infants.

Science.gov (United States)

Panya, Marutpong; Lulitanond, Viraphong; Rattanachaikunsopon, Pongsak; Srivoramas, Thanyakarn; Chaiwong, Tarinee

2016-01-01

To isolate, identify, and evaluate the probiotic properties of lactic acid bacteria (LAB) isolated from the feces of breast-fed infants. The probiotic tests included investigation of hemolysis activity, survival in simulated gastrointestinal tract conditions (acid and bile salt tolerance), susceptibility to antibiotics, and ability to inhibit selected bacterial pathogens (Escherichia coli O157:H7, Vibrio cholerae and Salmonella enterica subsp enterica serovar Typhimurium). The bacterial species identification was performed by both carbohydrate utilization and partial 16S ribosomal RNA sequencing. Five of fifty LAB isolates (UBU-03, UBU-06, UBU-09, UBU-34, and UBU-37) showed good probiotic properties. These five isolates showed non-hemolysis type (gamma-hemolysis), susceptibility to all antibiotics tested except for vancomycin, ability to survive in the simulated gastrointestinal conditions of both acid and bile salt solution, and ability to inhibit growth of E. coli O157: H7 and V. cholerae. Bacterial species identification revealed that all five isolates were firmly identified as Lactobacillus rhamnosus species. The L. rhamnosus strains that were isolated and characterized in this study could be considered as probiotic strains, and then used for further probiotic characterization in human cell cultures or animal models.

Project report - an overview of the project and experiences with project management

DEFF Research Database (Denmark)

Jørgensen, Michael Søgaard; Mikkelsen, Bent Egberg

1996-01-01

A collection of the project planning and the experiences with project management from the Catering 2000 project.As appendieces articles etc. from journals, newspapers etc. about the project.......A collection of the project planning and the experiences with project management from the Catering 2000 project.As appendieces articles etc. from journals, newspapers etc. about the project....

Staphylococcus epidermidis isolated in 1965 are more susceptible to triclosan than current isolates

DEFF Research Database (Denmark)

Skovgaard, Sissel; Nielsen, Lene Nørby; Larsen, Marianne Halberg

2013-01-01

pathogen Staphylococcus epidermidis with isolates collected in the 1960s prior to introduction of triclosan to the market. Of 64 current S. epidermidis isolates 12.5% were found to have tolerance towards triclosan defined as MIC≥0.25 mg/l compared to none of 34 isolates obtained in the 1960s. When passaged......Since its introduction to the market in the 1970s, the synthetic biocide triclosan has had widespread use in household and medical products. Although decreased triclosan susceptibility has been observed for several bacterial species, when exposed under laboratory settings, no in vivo studies have...... in the laboratory in the presence of triclosan, old and current susceptible isolates could be adapted to the same triclosan MIC level as found in current tolerant isolates. DNA sequence analysis revealed that laboratory-adapted strains carried mutations in fabI encoding the enoyl-acyl carrier protein reductase...

Different Babesia canis isolates, different diseases.

Science.gov (United States)

Schetters, T P; Moubri, K; Précigout, E; Kleuskens, J; Scholtes, N C; Gorenflot, A

1997-11-01

Using surface immunofluorescence isolate-specific antigens were detected on the membrane of erythrocytes infected with Babesia parasites. In addition, the strains reacted differently with Plasmagel in that the European isolate (B.c. canis) could be purified on Plasmagel effectively, whereas infected erythrocytes of the South-African isolate (B.c. rossi) could not. Experimental infection of dogs with Babesia canis isolates from geographically different areas revealed different pathology. The European isolate obtained from France exhibited transient parasitaemia, usually below 1%, associated with low PCV values and congestion of internal organs. Clinical disease was correlated with an effect on the coagulation system, and not with peripheral parasitaemia. Infection of dogs with South-African-derived isolate induced high parasitaemia usually much higher than 1%, which required chemotherapeutic treatment. In these animals clinical disease was correlated with peripheral parasitaemia and not with parameters of the coagulation system. The results show that the etiology of disease caused by these isolates of B.c. canis and B.c. rossi is different. This might have implications for the development of vaccines against these infections.

Dynamics of isolated-photon plus jet production in pp collisions at √s = 7 TeV with the ATLAS detector

Czech Academy of Sciences Publication Activity Database

Aad, G.; Abajyan, T.; Abbott, B.; Böhm, Jan; Chudoba, Jiří; Hejbal, Jiří; Jakoubek, Tomáš; Kepka, Oldřich; Kupčo, Alexander; Kůs, Vlastimil; Lokajíček, Miloš; Lysák, Roman; Marčišovský, Michal; Mikeštíková, Marcela; Myška, Miroslav; Němeček, Stanislav; Růžička, Pavel; Schovancová, Jaroslava; Šícho, Petr; Staroba, Pavel; Svatoš, Michal; Taševský, Marek; Tic, Tomáš; Vrba, Václav

2013-01-01

Roč. 875, č. 3 (2013), 483-535 ISSN 0550-3213 R&D Projects: GA MŠk(CZ) LG13009 Institutional support: RVO:68378271 Keywords : ATLAS * photon * isolated production * associated production * scattering * jet * transverse momentum * jet * rapidity * photon * transverse energy Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 3.946, year: 2013

Vibration isolation/suppression: research experience for undergraduates in mechatronics and smart structures

Science.gov (United States)

Fonda, James; Rao, Vittal S.; Sana, Sridhar

2001-08-01

This paper provides an account of a student research project conducted under the sponsoring of the National Science Foundation (NSF) program on Research Experience for Undergraduates (REU) in Mechatronics and Smart Strictures in the summer of 2000. The objective of the research is to design and test a stand-alone controller for a vibration isolation/suppression system. The design specification for the control system is to suppress the vibrations induced by the external disturbances by at least fiver times and hence to achieve vibration isolation. Piezo-electric sensors and actuators are utilized for suppression of unwanted vibrations. Various steps such as modeling of the system, controller design, simulation, closed-loop testing using d- Space rapid prototyping system, and analog control implementation are discussed in the paper. Procedures for data collection, the trade-offs carried out in the design, and analog controller implementation issues are also presented in the paper. The performances of various controllers are compared. The experiences of an undergraduate student are summarized in the conclusion of the paper.

Isolated Systolic Hypertension: A Health Concern?

Science.gov (United States)

Isolated systolic hypertension: A health concern? Is having a high top number (systolic) blood pressure, but a normal bottom number (diastolic) ... mm Hg, you have a common type of high blood pressure called isolated systolic hypertension. Isolated systolic hypertension can ...

Seismic isolation in New Zealand

International Nuclear Information System (INIS)

Skinner, R.I.; Robinson, W.H.; McVerry, G.H.

1989-01-01

Bridges, buildings, and industrial equipment can be given increased protection from earthquake damage by limiting the earthquake attack through seismic isolation. A broad summary of the seismic responses of base-isolated structures is of considerable assistance for their preliminary design. Seismic isolation as already used in New Zealand consists of a flexible base or support combined with some form of energy-dissipating device, usually involving the hysteretic working of steel or lead. This paper presents examples of the New Zealand experience, where seismic isolation has been used for 42 bridges, 3 buildings, a tall chimney, and high-voltage capacitor banks. Additional seismic response factors, which may be important for nuclear power plants, are also discussed briefly

Studies on the Needs of Seismic Base Isolation Concept and its Standardization

International Nuclear Information System (INIS)

Lee, Min-Seok; Kim, Jong-Hae

2015-01-01

seismic protection of the structures of nuclear facility rather than to solely depend on seismic resistance design alone. This can also bring cost reduction effects both in early construction and in disaster control aftermath. Domestically, various types of devices are used for seismic base isolation systems in bridge projects. The 2005 revised edition of 'the highway bridge design standard' includes seismic base isolation standards under seismic resistance design for the first time in history; however, no efforts have been made to implement this technology in other fields. Therefore, KEPIC is developing seismic base isolation technology standards for the electrical industry

Studies on the Needs of Seismic Base Isolation Concept and its Standardization

Energy Technology Data Exchange (ETDEWEB)

Lee, Min-Seok; Kim, Jong-Hae [Korea Electric Association, Seoul (Korea, Republic of)

2015-05-15

seismic protection of the structures of nuclear facility rather than to solely depend on seismic resistance design alone. This can also bring cost reduction effects both in early construction and in disaster control aftermath. Domestically, various types of devices are used for seismic base isolation systems in bridge projects. The 2005 revised edition of 'the highway bridge design standard' includes seismic base isolation standards under seismic resistance design for the first time in history; however, no efforts have been made to implement this technology in other fields. Therefore, KEPIC is developing seismic base isolation technology standards for the electrical industry.

Tiamulin resistance in porcine Brachyspira pilosicoli isolates.

Science.gov (United States)

Pringle, M; Landén, A; Franklin, A

2006-02-01

There are few studies on antimicrobial susceptibility of Brachyspira pilosicoli, therefore this study was performed to investigate the situation among isolates from pigs. The tiamulin and tylosin susceptibility was determined by broth dilution for 93 and 86 porcine B. pilosicoli isolates, respectively. The isolates came from clinical samples taken in Swedish pig herds during the years 2002 and 2003. The tylosin minimal inhibitory concentration (MIC) was >16 microg/ml for 50% (n=43) of the isolates tested. A tiamulin MIC >2 microg/ml was obtained for 14% (n=13) of the isolates and these were also tested against doxycycline, salinomycin, valnemulin, lincomycin and aivlosin. For these isolates the susceptibility to salinomycin and doxycycline was high but the MICs for aivlosin varied. The relationship between the 13 tiamulin resistant isolates was analyzed by pulsed-field gel electrophoresis (PFGE). Among the 13 isolates 10 different PFGE patterns were identified.

The integrated in situ testing program for the Waste Isolation Pilot Plant (WIPP)

International Nuclear Information System (INIS)

Matalucci, R.V.

1987-03-01

The US Department of Energy (DOE) is developing the Waste Isolation Pilot Plant (WIPP) Project in southeastern New Mexico as a research and development (R and D) facility for examining the response of bedded (layered) salt to the emplacement of radioactive wastes generated from defense programs. The WIPP Experimental Program consists of a technology development program, including laboratory testing and theoretical analysis activities, and an in situ testing program that is being done 659 m underground at the project site. This experimental program addresses three major technical areas that concern (1) thermal/structural interactions, (2) plugging and sealing, and (3) waste package performance. To ensure that the technical issues involved in these areas are investigated with appropriate emphasis and timing, an in situ testing plan was developed to integrate the many activities and tasks associated with the technical issues of waste disposal. 5 refs., 4 figs

Assessing Social Isolation: Pilot Testing Different Methods.

Science.gov (United States)

Taylor, Harry Owen; Herbers, Stephanie; Talisman, Samuel; Morrow-Howell, Nancy

2016-04-01

Social isolation is a significant public health problem among many older adults; however, most of the empirical knowledge about isolation derives from community-based samples. There has been less attention given to isolation in senior housing communities. The objectives of this pilot study were to test two methods to identify socially isolated residents in low-income senior housing and compare findings about the extent of isolation from these two methods. The first method, self-report by residents, included 47 out of 135 residents who completed in-person interviews. To determine self-report isolation, residents completed the Lubben Social Network Scale 6 (LSNS-6). The second method involved a staff member who reported the extent of isolation on all 135 residents via an online survey. Results indicated that 26% of residents who were interviewed were deemed socially isolated by the LSNS-6. Staff members rated 12% of residents as having some or a lot of isolation. In comparing the two methods, staff members rated 2% of interviewed residents as having a lot of isolation. The combination of self-report and staff report could be more informative than just self-report alone, particularly when participation rates are low. However, researchers should be aware of the potential discrepancy between these two methods.

Signal validation of SPDS variables for Westinghouse and Combustion Engineering plants - an EPRI project

International Nuclear Information System (INIS)

Anon.

1987-01-01

Signal validation in the context of this project is the process of combining information from multiple plant sensors to produce highly reliable information about plant conditions. High information reliability is achieved by the use of redundant sources of information and by the inherent detection, identification, and isolation of faulty signals. The signal validation methodology that has been developed in previous EPRI-sponsored projects has been enhanced and applied toward validation of critical safety-related SPDS signals in the Northeast Utilities Millstone 3 Westinghouse PWR plant and the Millstone 2 Combustion Engineering PWR plant. The designs were implemented in FORTRAN software and tested off-line using recorded plant sensor data, RETRAN-generated simulation data, and data to exercise software logic branches and the integration of software modules. Designs and software modules have been developed for 15 variables to support six PWR SPDS critical safety functions as required by a utility advisory group attached to the project. The signal validation process automates a task currently performed by plant operators and does so with consistent, verified logic regardless of operator stress and training level. The methodology uses a simple structure of generic software blocks, a modular implementation, and it performs effectively within the processor and memory constraints of modern plant process computers. The ability to detect and isolate sensor failures with greater sensitivity, robustness, and coverage of common-cause failures should ultimately lead to improved plant availability, efficiency, and productivity

Miniature Optical Isolator, Phase II

Data.gov (United States)

National Aeronautics and Space Administration — To address NASA's need for compact optical isolators, Physical Optics Corporation (POC) proposes to continue the development of a new Miniature Optical Isolator...

Functions and requirements document, WESF decoupling project, low-level liquid waste system

Energy Technology Data Exchange (ETDEWEB)

Rasmussen, J.H., Fluor Daniel Hanford

1997-02-27

The Waste Encapsulation and Storage Facility (WESF) was constructed in 1974 to encapsulate and store cesium and strontium which were isolated at B Plant from underground storage tank waste. The WESF, Building 225-B, is attached physically to the west end of B Plant, Building 221-B, 200 East area. The WESF currently utilizes B Plant facilities for disposing liquid and solid waste streams. With the deactivation of B Plant, the WESF Decoupling Project will provide replacement systems allowing WESF to continue operations independently from B Plant. Four major systems have been identified to be replaced by the WESF Decoupling Project, including the following: Low Level Liquid Waste System, Solid Waste Handling System, Liquid Effluent Control System, and Deionized Water System.

Preventing social isolation in older people.

Science.gov (United States)

Cotterell, Natalie; Buffel, Tine; Phillipson, Christopher

2018-07-01

The extent of social isolation amongst older people has emerged as a major concern for health and social policy. Although the social and health outcomes of social isolation are well documented, evidence regarding the prevention of isolation in later life remains scarce. This article addresses this by presenting the findings from a literature review focusing on the identification, assessment, prevention, and intervention strategies relevant to social isolation in older age. The paper first addresses the issues of identification and assessment, using an ecological framework to identify the risk factors for social isolation at four levels: individual, relationship, community, and societal. It then reviews different types of interventions to reduce or prevent social isolation in later life, including one-to-one, group, service provision, technology-based, neighbourhood, and structural interventions. The paper discusses both the opportunities and the constraints associated with these different approaches. The discussion highlights future directions for research, emphasising the need for a cultural change from 'cure' to 'prevention' of social isolation across the life-course, and the importance of acknowledging greater diversity within the ageing population. Copyright © 2018 Elsevier B.V. All rights reserved.

A universal protocol for the combined isolation of metabolites, DNA, long RNAs, small RNAs, and proteins from plants and microorganisms

Czech Academy of Sciences Publication Activity Database

Valledor, Luis; Escandón, M.; Meijón, M.; Nukarinen, E.; Jesús Cañal, M.; Weckwerth, W.

2014-01-01

Roč. 79, č. 1 (2014), s. 173-180 ISSN 0960-7412 R&D Projects: GA MŠk(CZ) EE2.3.20.0256 Institutional support: RVO:67179843 Keywords : systems biology * combined isolation * RNA * small RNA * proteins * metabolites * Chlamydomonas reinhardtii * Arabidopsis thaliana * Populus sp. * Pinus sp. * technical advance Subject RIV: EI - Biotechnology ; Bionics Impact factor: 5.972, year: 2014

Genetic diversity among brazilian isolates of beauveria bassiana: comparisons with non-brazilian isolates and other beauveria species

Science.gov (United States)

Fernandes, E.K.K.; Moraes, A.M.L.; Pacheco, R.S.; Rangel, D.E.N.; Miller, M.P.; Bittencourt, V.R.E.P.; Roberts, D.W.

2009-01-01

Aims: The genetic diversity of Beauveria bassiana was investigated by comparing isolates of this species to each other (49 from different geographical regions of Brazil and 4 from USA) and to other Beauveria spp. Methods and Results: The isolates were examined by multilocus enzyme electrophoresis (MLEE), amplified fragment length polymorphism (AFLP), and rDNA sequencing. MLEE and AFLP revealed considerable genetic variability among B. bassiana isolates. Several isolates from South and Southeast Brazil had high similarity coefficients, providing evidence of at least one population with clonal structure. There were clear genomic differences between most Brazilian and USA B. bassiana isolates. A Mantel test using data generated by AFLP provided evidence that greater geographical distances were associated with higher genetic distances. AFLP and rDNA sequencing demonstrated notable genotypic variation between B. bassiana and other Beauveria spp. Conclusion: Geographical distance between populations apparently is an important factor influencing genotypic variability among B. bassiana populations in Brazil. Significance and Impact of the Study: This study characterized many B. bassiana isolates. The results indicate that certain Brazilian isolates are considerably different from others and possibly should be regarded as separate species from B. bassiana sensu latu. The information on genetic variation among the Brazilian isolates, therefore, will be important to comprehending the population structure of B. bassiana in Brazil. ?? 2009 The Society for Applied Microbiology.

Antagonistic Activity of Trichoderma ISolates against Sclerotium rolfsii : Screening of Efficient Isolates from Morocco Soils for Biological Control

Directory of Open Access Journals (Sweden)

N. Khattabi

2004-12-01

Full Text Available Seventy Trichoderma spp. isolates collected from different regions of Morocco were tested for their capacity to inhibit in vitro mycelial growth of Sclerotium rolfsii, and for their effect on the viability of S. rolfsii sclerotia in the soil. The Trichoderma spp. isolates inhibited mycelial growth of S. rolfsii to various degrees, with 52% of isolates expressing an average inhibition, varying between 45 and 55%. The effect on the viability of sclerotia in the soil also varied between isolates of Trichoderma, with the majority (84% having a slight effect. A group of twenty isolates identified as Trichoderma harzianum when tested in sterilized soil, significantly reduced sclerotial viability though not in natural soil. Four of these isolates (Nz, Kb2, Kb3 and Kf1 showed good antagonistic activity against S. rolfsii and were also highly competitive in natural soil. These isolates would therefore be candidates for development in biological control program.

Sensitivity of seismically isolated structures

International Nuclear Information System (INIS)

Politopoulos, I.; Hoan, Khac Pham

2009-01-01

In this paper we study the sensitivity of seismically isolated structures to a small variability of the earthquake excitation and of some structural properties with respect to the probability of failure and floor spectra. In particular, the influence of the nonlinear behaviour of the isolated superstructure on the vulnerability and on the floor spectra is investigated by means of a series of Monte Carlo simulations of simple two degrees-of-freedom systems. Several types of passive and active isolation systems are examined and three different idealized nonlinear constitutive laws are considered for the superstructure. It is found that, in general, the probability of failure does not depend on the specific cyclic behaviour of the assumed constitutive law and general trends regarding the impact of different isolation devices on vulnerability are established. As for the floor spectra, the influence of moderate nonlinear behaviour of isolated Superstructures, with the exception of the case of a non-dissipative elastic nonlinear law is negligible, contrary to the case of conventional Structures. (authors)

Sensitivity of seismically isolated structures

Energy Technology Data Exchange (ETDEWEB)

Politopoulos, I. [CEA Saclay, DEN DANS DM2S, 91 - Gif sur Yvette (France); Hoan, Khac Pham

2009-07-15

In this paper we study the sensitivity of seismically isolated structures to a small variability of the earthquake excitation and of some structural properties with respect to the probability of failure and floor spectra. In particular, the influence of the nonlinear behaviour of the isolated superstructure on the vulnerability and on the floor spectra is investigated by means of a series of Monte Carlo simulations of simple two degrees-of-freedom systems. Several types of passive and active isolation systems are examined and three different idealized nonlinear constitutive laws are considered for the superstructure. It is found that, in general, the probability of failure does not depend on the specific cyclic behaviour of the assumed constitutive law and general trends regarding the impact of different isolation devices on vulnerability are established. As for the floor spectra, the influence of moderate nonlinear behaviour of isolated Superstructures, with the exception of the case of a non-dissipative elastic nonlinear law is negligible, contrary to the case of conventional Structures. (authors)

Isolation, characterization and identification of actinomycetes from ...

African Journals Online (AJOL)

A total of 62 isolates of actinomycetes were isolated from 7 soil samples collected from Agriculture Research Center Semongok, Sarawak. All 62 isolates exhibited a range of colony colours (dark grey, grey, dark brown, brownish, whitish and yellowish white). All the isolates were later purified and subjected to a few ...

Identity of streptococcal blood isolates and oral isolates from two patients with infective endocarditis

DEFF Research Database (Denmark)

Fiehn, N E; Gutschik, E; Larsen, Tove

1995-01-01

The purpose of this study was to isolate streptococcal strains from the oral cavities of streptococcal endocarditis patients and compare these strains biochemically and genetically with the corresponding streptococcal blood isolates. Total identity was observed between the blood and oral cavity...

Status of SPIRAL. The radioactive beam project at GANIL

International Nuclear Information System (INIS)

Lieuvin, M.

1995-01-01

SPIRAL, a radioactive ion beam facility (RIB) is under construction at GANIL (Caen, France). The heavy ion beams of GANIL will be used to produce radioactive atoms by the ISOL method. After ionisation by an ECR ion source (ECRIS), the low energy radioactive beam is axially injected on the first orbit of a k=265 compact cyclotron. The final energy will range between 1.7 and 25 MeV/u (harmonics 5 to 2) and the accelerated ions will be sent to the existing GANIL experimental areas. The present status of the project is described. (author)

Age-related associative deficits and the isolation effect.

Science.gov (United States)

Badham, Stephen P; Maylor, Elizabeth A

2013-01-01

If all but one of the items in a list are similar (e.g., all black except one red), memory for the different item is enhanced (the isolation effect). Older adults generally show similar or smaller isolation effects compared to young adults, which has been attributed to age-related deficits in associative memory whereby older adults are less able to associate an isolated stimulus to its isolating feature. Experiment 1 examined the isolation effect for isolation based on spatial position, modality and color; in Experiment 2, the criterion for isolation was the associative relation between stimuli. The results consistently showed no differences between young and older participants in the magnitude of the isolation effect. Whilst age deficits in associative memory may act to reduce the isolation effect in older adults, age deficits in self-initiated processing and inhibitory functionality may counteract this reduction by enhancing the isolation effect in older adults.

Waste isolation safety assessment program

International Nuclear Information System (INIS)

Brandstetter, A.; Harwell, M.A.

1979-05-01

Associated with commercial nuclear power production in the United States is the generation of potentially hazardous radioactive wastes. The Department of Energy (DOE), through the National Waste Terminal Storage (NWTS) Program, is seeking to develop nuclear waste isolation systems in geologic formations that will preclude contact with the biosphere of waste radionuclides in concentrations which are sufficient to cause deleterious impact on humans or their environments. Comprehensive analyses of specific isolation systems are needed to assess the expectations of meeting that objective. The Waste Isolation Safety Assessment Program (WISAP) has been established at the Pacific Northwest Laboratory (operated by Battelle Memorial Institute) for developing the capability of making those analyses. Among the analyses required for isolation system evaluation is the detailed assessment of the post-closure performance of nuclear waste repositories in geologic formations. This assessment is essential, since it is concerned with aspects of the nuclear power program which previously have not been addressed. Specifically, the nature of the isolation systems (e.g., involving breach scenarios and transport through the geosphere), and the time-scales necessary for isolation, dictate the development, demonstration and application of novel assessment capabilities. The assessment methodology needs to be thorough, flexible, objective, and scientifically defensible. Further, the data utilized must be accurate, documented, reproducible, and based on sound scientific principles

Engineering solutions to the long-term stabilization and isolation of uranium mill tailings in the United States

International Nuclear Information System (INIS)

Sanders, D.R.; Lommler, J.C.

1995-01-01

Engineering solutions to the safe and environmentally protective disposal and isolation of uranium mill tailings in the US include many factors. Cover design, materials selection, civil engineering, erosive forces, and cost effectiveness are only a few of those factors described in this paper. The systems approach to the engineering solutions employed in the US is described, with emphasis on the standards prescribed for the Uranium Mill Tailings Remedial Action Project. Stabilization and isolation of the tailings from humans and the environment are the primary goals of the US uranium mill tailings control standards. The performance of cover designs with respect to water infiltration, radon exhalation, geotechnical stability, erosion protection, human and animal intrusion prevention, and longevity are addressed. The need for and frequency of surveillance efforts to ensure continued disposal system performance are also assessed

Geological problems in radioactive waste isolation - A world wide review

Energy Technology Data Exchange (ETDEWEB)

Witherspoon, P.A. [Lawrence Berkeley Lab., CA (United States)

1991-06-01

The problem of isolating radioactive wastes from the biosphere presents specialists in the earth sciences with some of the most complicated problems they have ever encountered. This is especially true for high-level waste (HLW), which must be isolated in the underground and away from the biosphere for thousands of years. The most widely accepted method of doing this is to seal the radioactive materials in metal canisters that are enclosed by a protective sheath and placed underground in a repository that has been carefully constructed in an appropriate rock formation. Much new technology is being developed to solve the problems that have been raised, and there is a continuing need to publish the results of new developments for the benefit of all concerned. Table 1 presents a summary of the various formations under investigation according to the reports submitted for this world wide review. It can be seen that in those countries that are searching for repository sites, granitic and metamorphic rocks are the prevalent rock type under investigation. Six countries have developed underground research facilities that are currently in use. All of these investigations are in saturated systems below the water table, except the United States project, which is in the unsaturated zone of a fractured tuff.

Probabilistic cost estimating of nuclear power plant construction projects

International Nuclear Information System (INIS)

Finch, W.C.; Perry, L.W.; Postula, F.D.

1978-01-01

This paper shows how to identify and isolate cost accounts by developing probability trees down to component levels as justified by value and cost uncertainty. Examples are given of the procedure for assessing uncertainty in all areas contributing to cost: design, factory equipment pricing, and field labor and materials. The method of combining these individual uncertainties is presented so that the cost risk can be developed for components, systems and the total plant construction project. Formats which enable management to use the probabilistic cost estimate information for business planning and risk control are illustrated. Topics considered include code estimate performance, cost allocation, uncertainty encoding, probabilistic cost distributions, and interpretation. Effective cost control of nuclear power plant construction projects requires insight into areas of greatest cost uncertainty and a knowledge of the factors which can cause costs to vary from the single value estimates. It is concluded that probabilistic cost estimating can provide the necessary assessment of uncertainties both as to the cause and the consequences

The Los Alamos National Laboratory Transuranic Waste Retireval Project

International Nuclear Information System (INIS)

Montoya, G.M.; Christensen, D.V.; Stanford, A.R.

1997-01-01

This paper presents the status of the Los Alamos National Laboratory (LANL) project for remediation of transuranic (TRU) and TRU mixed waste from Pads 1, 2, and 4. Some of the TRU waste packages retrieved from Pad I are anticipated to be part of LANL's initial inventory to be shipped to the Waste Isolation Pilot Plant (WIPP) in April 1998. The TRU Waste Inspectable Storage Project (TWISP) was initiated in February 1993 in response to the New Mexico Environment Department's (NMED's) Consent Agreement for Compliance Order, ''New Mexico Hazardous Waste Agreement (NMHWA) 93-03.'' The TWISP involves the recovery of approximately 16,865 TRU and TRU-mixed waste containers currently under earthen cover on Pads 1, 2, and 4 at Technical Area 54, Area G, and placement of that waste into inspectable storage. All waste will be moved into inspectable storage by September 30, 2003. Waste recovery and storage operations emphasize protection of worker safety, public health, and the environment

One project`s waste is another project`s resource

Energy Technology Data Exchange (ETDEWEB)

Short, J.

1997-02-01

The author describes the efforts being made toward pollution prevention within the DOE complex, as a way to reduce overall project costs, in addition to decreasing the amount of waste to be handled. Pollution prevention is a concept which is trying to be ingrained into project planning. Part of the program involves the concept that ultimately the responsibility for waste comes back to the generator. Parts of the program involve efforts to reuse materials and equipment on new projects, to recycle wastes to generate offsetting revenue, and to increase awareness, accountability and incentives so as to stimulate action on this plan. Summaries of examples are presented in tables.

Experiments on seismic isolation in Italy

International Nuclear Information System (INIS)

Bonacina, G.; Bettinali, F.; Martelli, A.; Olivieri, M.

1992-01-01

Static and dynamic tests have been performed in Italy on high damping steel-laminated elastomer bearings in various scales, rubber specimens and structures isolated by means of such bearings, in the framework of studies in progress to support seismic isolation development. Tests on rubber specimens and bearings have already provided important data (vertical and horizontal stiffness, damping, creep, temperature, aging and scale effects, etc.), necessary for the development and validation of numerical models, comparison with the test results of isolated structure mockups and actual buildings, and improvement of design guidelines. Dynamic experiments of structures concerned both full-scale and scaled isolated structure mock-ups and actual isolated buildings (one of those forming the SIP Administration Center at Ancona, an isolated house at Squillace, Calabria). Both snap-back tests and forced excitation experiments were performed, to rather large displacements. The latter were both sinusoidal and (on a 1/4 scale mock-up) seismic, with one- and multidirectional simultaneous excitations. Test results have already demonstrated the adequacy of seismic isolation and have provided data useful for the comparison with single bearing test results and validation of numerical models for the analysis of isolated structures. This paper reports the main features and results of tests performed or in progress. Further tests planned have been mentioned in the Status Report. Numerical analysis of measured data and guidelines development have been discussed in separate technical papers. (author)

[The isolation and characterization of beta-glucosidase gene and beta-glucosidase of Trichoderma viride]: Progress report

International Nuclear Information System (INIS)

Stafford, D.W.

1983-01-01

Our project was to isolate and characterize the enzyme β-glucosidase and to clone and characterize the β-glucosidase gene; our goal is to clone and characterize each of the cellulase genes from Trichoderma. The induction of the Trichoderma reesei cellulase complex by cellulose and by the soluble inducer, sophorose, has been demonstrated. Although the induction of the cellulase complex has previously been well documented, the induction of β-glucosidase had been questioned. 49 refs., 6 figs., 2 tabs

Offsite testing in support of the Salt Repository Project

International Nuclear Information System (INIS)

Kalia, H.N.

1987-04-01

This report presents a rationale and recommendation to perform an offsite testing program in support of the Salt Repository Project. The investigation to be performed primarily consists of qualifying test methods and procedures, qualifying personnel-training procedures, evaluating test instruments and selected equipment, and obtaining mining and production equipment performance-related information. The key objective of these activities is to develop capabilities to be used at the exploratory shaft facility (ESF). The ESF is to be excavated at the Deaf Smith County site to characterize the salt site for the construction of a repository used to isolate radioactive waste from the biosphere. The bulk of the offsite testing work will be performed at Avery Island Salt Mine at New Iberia, Lousiana. Additional knowledge will be obtained by exchanging technical information either as participants or as observers at the Waste Isolation Pilot Plant (WIPP) site and the Asse Mine in the Federal Republic of Germany (FRG). It is estimated that the offsite testing program will cost approximately $9.3 million over 4 fiscal years. 14 refs., 1 fig., 8 tabs

FEATURES OF THE PROJECT-ORIENTED MANAGEMENT OF HIGH-TECHNOLOGY ENTERPRISES

Directory of Open Access Journals (Sweden)

E. D. Dobrova

2016-01-01

Full Text Available This article is explored the concept of "project portfolio", defined the role and place of project portfolio management in the overall enterprise management structure, the formation of the project portfolio and its limitations. The aim of the article is to study the role and place of project management in the overall enterprise management system, and the relationship of the management processes at diff erent organizational levels.The formation of the strategic projects portfolio of the company – it is an urgent task which is associated with the strengthening of innovation and investment activity of the operating in Russia enterprises. Nowadays, transfer of enterprises activities to an innovative way of development is going on in the face of the deteriorating international situation, Russia's isolation from European countries and the United States, and the implementation of the sanctions policy, changes in the domestic economic and political course. These circumstances, of course, could not aff ect the adjustment of activities and strategic goals of the development of enterprises, at the level of their financial and economic stability. At the same time, the growth of innovation activity in a number of sectors, particularly in high-technology industries, it creates the need for the formation of the project portfolio, which allows to achieve the strategic objectives of enterprises and enhance their competitiveness.During the preparation of the article there were identified a core set of problems faced by the enterprises during the transition to a model of the project management, which is due, primarily, poor project management technologies in Russia, and it is complicated by the lack of a clear definition of objectives and vision benefits for enterprises. In addition, the reasons for the backlog are caused by the low level of project management maturity of the enterprise, which is caused by a lack of personnel with expertise in this field of

Isolation, characterization, and evaluation of wild isolates of Lactobacillus reuteri from pig feces.

Science.gov (United States)

Lee, Deog Yong; Seo, Yeon-Soo; Rayamajhi, Nabin; Kang, Mi Lan; Lee, Su In; Yoo, Han Sang

2009-12-01

Lactic acid bacteria (LAB) are a well-used probiotics for health improvements in both humans and animals. Despite of several benefits, non-host-specific LAB showed poor probiotics effects due to difficulty in colonization and competition with normal flora. Therefore, the feasibility of porcine LAB isolates was evaluated as a probiotics. Ten of 49 Lactobacillus spp. isolates harbored 2 approximately 10 kb plasmid DNA. Seven strains were selected based on the safety test, such as hemolytic activity, ammonia, indole, and phenylalanine production. After safety test, five strains were selected again by several tests, such as epithelial adherence, antimicrobial activity, tolerance against acid, bile, heat, and cold-drying, and production of acid and hydrogen peroxide. Then, enzyme profiles (ZYM test) and antibiotics resistance were analyzed for further characterization. Five Lactobacillus reuteri isolates from pig feces were selected by safety and functional tests. The plasmid DNA which was able to develop vector system was detected in the isolates. Together with these approaches, pig-specific Lactobacillus spp. originated from pigs were selected. These strains may be useful tools to develop oral delivery system.

Guidebook on the development of projects for uranium mining and ore processing

International Nuclear Information System (INIS)

1991-04-01

Bringing a uranium operation into production involves a sequence of interrelated steps. These are outlined in the simplified diagram of Fig. 1. The challenge is to determine how the various steps of the development sequence should function and whether the costs are sufficiently low to return a positive benefit to the owner. This Guidebook has been prepared to aid in the planning, development and implementation of feasible uranium projects. It is one in a series of publications by the IAEA. This guidebook is essentially the executive summary of the other publications. It is an overview of the systematic approach to project development. It might be viewed as the ''road map'' of a project. A list of other publications in this series is provided in the Bibliography. Each chapter of the Guidebook addresses a critical aspect of project development. Chapters follow a general sequence, but none should be considered in isolation. Each Chapter presents an overview of the requirements for reaching decisions necessary to advance a project. References are provided to more definitive information and to documents which will be required by technical personnel on a project. Such detailed publications include IAEA books such as ''An Instruction Manual on Methods for Estimation of Uranium Ore Reserves'', and the ''Significance of Mineralogy in the Development of Flow Sheets for Processing Uranium Ores''. This Guidebook does not detail how to do project development but rather what must be done to insure that all critical elements of a project are considered. Refs, figs and tabs

Reducing social isolation and loneliness in older people: a systematic review protocol.

Science.gov (United States)

Landeiro, Filipa; Barrows, Paige; Nuttall Musson, Ellen; Gray, Alastair M; Leal, José

2017-05-17

Social isolation and loneliness affect approximately one-third to one-half of the elderly population and have a negative impact on their physical and mental health. Group-based interventions where facilitators are well trained and where the elderly are actively engaged in their development seem to be more effective, but conclusions have been limited by weak study designs. We aim to conduct a systematic review to assess the effectiveness of health promotion interventions on social isolation or loneliness in older people. A systematic review was conducted in Medline, Embase, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Applied Social Sciences Index and Abstracts, LILACS, OpenGrey and the Cochrane Library on peer-reviewed studies and doctoral theses published between 1995 and 2016 evaluating the impact of health promotion interventions on social isolation and/or loneliness for individuals aged 60 and over. Two reviewers will independently assess each study for inclusion and disagreements will be resolved by a third reviewer. Data will be extracted using a predefined pro forma following best practice. Study quality will be assessed with the Effective Public Health Practice Project quality assessment tool. A narrative synthesis of all studies will be presented by type of outcome (social isolation or loneliness) and type of intervention. If feasible, the effectiveness data will be synthesised using appropriate statistical techniques. This systematic review is exempt from ethics approval because the work is carried out on published documents. The findings of the review will be disseminated in a related peer-reviewed journal and presented at conferences. They will also contribute to a DPhil thesis. CRD42016039650. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Using the Lashof Accounting Methodology to Assess Carbon Mitigation Projects Using LCA: Ethanol Biofuel as a Case Study

DEFF Research Database (Denmark)

Courchesne, Alexandre; Becaert, Valerie; Rosenbaum, Ralph K.

2010-01-01

and comparison of different carbon mitigation projects (e.g. biofuel use, sequestering plant, afforestation project, etc.). The Lashof accounting methodology is chosen amid other methods of greenhouse gas (GHG) emission characterization for its relative simplicity and capability of characterizing all types...... of carbon mitigation projects. It calculates the cumulative radiative forcing caused by GHG emission within a predetermined time frame. Basically, the developed framework uses the Mg-year as a functional unit and isolates impacts related to the climate mitigation function with system expansion. The proposed...... framework is demonstrated with a case study of tree ethanol pathways (maize, sugarcane and willow). Study shows that carbon mitigation assessment through LCA is possible and that it could be a useful tool for decision makers as it can compare different projects regardless of their original context. Case...

Pasteurella multocida isolated from wild birds of North America: a serotype and DNA fingerprint study of isolates from 1978 to 1993

Science.gov (United States)

Wilson, M.A.; Duncan, R.M.; Nordholm, G.E.; Berlowski, B.M.

1995-01-01

Serotype and DNA fingerprint methods were used to study Pasteurella multocida isolated from 320 wild birds of North America. Isolates were collected during 1978-93. The HhaI profiles of 314 isolates matched the HhaI profile of somatic reference type 1, strain X-73; somatic type 1 antigen was expressed by 310 isolates, and the serotype of four isolates was undetected. Differentiation of the 314 isolates was observed by digestion of DNA with HpaII. None of the HpaII profiles matched the HpaII profile of X-73 (designated HhaI 001/HpaII 001). Three HpaII profiles were recognized among the somatic type 1 isolates: HpaII 002 (n = 18), HpaII 003 (n = 122), and HpaII 004 (n = 174). Profile HpaII 002 was found among isolates collected during 1979-83. Profile HpaII 003 was identified from isolates collected during 1979-89, with the exception of two isolates in 1992. The HpaII 004 profile was identified from isolates collected during 1983-93. Of the six remaining isolates, four expressed somatic type 4 and had HhaI profiles identical to the somatic type 4 reference strain P-1662 profile (designated HhaI 004); these isolates were differentiated by digestion of DNA with HpaII. One isolate was identified as serotype F:11, and another was serotype A:3,4. In the present study, 314 of 316 (99.4%) isolates from wild birds in the Central, Mississippi, and Pacific flyways during 1978-93, were P. multocida somatic type 1.

Silica-coated La.sub.0.75./sub.Sr.sub.0.25./sub.MnO.sub.3./sub. nanoparticles for magnetically driven DNA isolation

Czech Academy of Sciences Publication Activity Database

Trachtová, Š.; Kaman, Ondřej; Španová, A.; Veverka, Pavel; Pollert, Emil; Rittich, B.

2011-01-01

Roč. 34, č. 21 (2011), s. 3077-3082 ISSN 1615-9306 R&D Projects: GA AV ČR KAN200200651 Institutional research plan: CEZ:AV0Z10100521 Keywords : DNA isolation * lanthanum manganese perovskite * nanoparticles Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.733, year: 2011

Project Success in IT Project Management

OpenAIRE

Siddiqui, Farhan Ahmed

2010-01-01

The rate of failed and challenged Information Technology (IT) projects is too high according to the CHAOS Studies by the Standish Group and the literature on project management (Standish Group, 2008). The CHAOS Studies define project success as meeting the triple constraints of scope, time, and cost. The criteria for project success need to be agreed by all parties before the start of the project and constantly reviewed as the project progresses. Assessing critical success factors is another ...

Vague project start makes project success of outsourced software development projects uncertain

OpenAIRE

Savolainen, Paula

2010-01-01

peer-reviewed A definition of a project success includes at least three criteria: 1) meeting planning goals, 2) customer benefits, and 3) supplier benefits. This study aims to point out the importance of the definition of the project start, the project start date, and what work should be included in the project effort in order to ensure the supplier's benefits. The ambiguity of the project start risks the profitability of the project and therefore makes project success at least from suppli...

Study of the Mechanical Properties and Vibration Isolation Performance of a Molecular Spring Isolator

Directory of Open Access Journals (Sweden)

Muchun Yu

2016-01-01

Full Text Available Molecular Spring Isolator (MSI is a novel passive vibration isolation technique, providing High-Static-Low-Dynamic (HSLD stiffness based on the use of molecular spring material. The molecular spring material is a solid-liquid mixture consisting of water and hydrophobic nanoporous materials. Under a certain level of external pressure, water molecules can intrude into the hydrophobic pores of nanoporous materials, developing an additional solid-liquid interface. Such interfaces are able to store, release, and transform mechanical energy, providing properties like mechanical spring. Having been only recently developed, the basic mechanic properties of a MSI have not been studied in depth. This paper focuses on the stiffness influence factors, the dynamic frequency response, and the vibration isolation performance of a MSI; these properties help engineers to design MSIs for different engineering applications. First, the working mechanism of a MSI is introduced from a three-dimensional general view of the water infiltration massive hydrophobic nanoporous pores. Next, a wide range of influence factors on the stiffness properties of MSI are studied. In addition, the frequency response functions (FRFs of the MSI vibration isolation system are studied utilizing the matching method based on equivalent piecewise linear (EPL system. Finally, the vibration isolation properties of MSI are evaluated by force transmissibility.

Isolated optic nerve pseudotumour

International Nuclear Information System (INIS)

Patankar, T.; Prasad, S.; Krishnan, A.; Laxminarayan, R.

2000-01-01

Isolated optic nerve involvement by the idiopathic inflammatory process is a rare finding and very few reports are available. Here a case of an isolated optic nerve inflammatory pseudotumour presenting with gradually progressive unilateral loss of vision is described. It showed dramatic response to a trial of steroids and its differential diagnoses are discussed. Copyright (1999) Blackwell Science Pty Ltd

Project management: a case of fixed price IS/IT projects. Analysis of projects by project scopes

Directory of Open Access Journals (Sweden)

Miroslav Kral

2012-10-01

Full Text Available The paper provides an overview of major issues of IS / IT projects. Attention will be focused on projects that are implemented under a contract for a specified amount of work and fixed price. The main purpose of the paper is to analyse the project parameters in terms of the types of projects, and to confirm, or refuse, a hypothesis related to this. There is some evidence from the portfolio of projects that have been implemented by the international companies providing IT services. Regarding the localisation, CEE region was selected for our research. The outputs of the paper should be a contribution to managing IS/IT projects in IT service delivery organizations and for the support of innovative thinking about project management generally.

Comparison of maximum intensity projection and digitally reconstructed radiographic projection for carotid artery stenosis measurement

International Nuclear Information System (INIS)

Hyde, Derek E.; Habets, Damiaan F.; Fox, Allan J.; Gulka, Irene; Kalapos, Paul; Lee, Don H.; Pelz, David M.; Holdsworth, David W.

2007-01-01

Digital subtraction angiography is being supplanted by three-dimensional imaging techniques in many clinical applications, leading to extensive use of maximum intensity projection (MIP) images to depict volumetric vascular data. The MIP algorithm produces intensity profiles that are different than conventional angiograms, and can also increase the vessel-to-tissue contrast-to-noise ratio. We evaluated the effect of the MIP algorithm in a clinical application where quantitative vessel measurement is important: internal carotid artery stenosis grading. Three-dimensional computed rotational angiography (CRA) was performed on 26 consecutive symptomatic patients to verify an internal carotid artery stenosis originally found using duplex ultrasound. These volumes of data were visualized using two different postprocessing projection techniques: MIP and digitally reconstructed radiographic (DRR) projection. A DRR is a radiographic image simulating a conventional digitally subtracted angiogram, but it is derived computationally from the same CRA dataset as the MIP. By visualizing a single volume with two different projection techniques, the postprocessing effect of the MIP algorithm is isolated. Vessel measurements were made, according to the NASCET guidelines, and percentage stenosis grades were calculated. The paired t-test was used to determine if the measurement difference between the two techniques was statistically significant. The CRA technique provided an isotropic voxel spacing of 0.38 mm. The MIPs and DRRs had a mean signal-difference-to-noise-ratio of 30:1 and 26:1, respectively. Vessel measurements from MIPs were, on average, 0.17 mm larger than those from DRRs (P<0.0001). The NASCET-type stenosis grades tended to be underestimated on average by 2.4% with the MIP algorithm, although this was not statistically significant (P=0.09). The mean interobserver variability (standard deviation) of both the MIP and DRR images was 0.35 mm. It was concluded that the MIP

Tanadgusix Foundation Hydrogen / Plug In Electric Vehicle Project

Energy Technology Data Exchange (ETDEWEB)

Miller, Martin [TDX Power Inc., Anchorage, AK (United States)

2013-09-27

TDX Foundation undertook this project in an effort to evaluate alternative transportation options and their application in the community of Saint Paul, Alaska an isolated island community in the Bering Sea. Both hydrogen and electric vehicle technology was evaluated for technical and economic feasibility. Hydrogen technology was found to be cost prohibitive. TDX demonstrated the implementation of various types of electric vehicles on St. Paul Island, including side-by-side all terrain vehicles, a Chevrolet Volt (sedan), and a Ford Transit Connect (small van). Results show that electric vehicles are a promising solution for transportation needs on St. Paul Island. Limited battery range and high charging time requirements result in decreased usability, even on a small, isolated island. These limitations were minimized by the installation of enhanced charging stations for the car and van. In collaboration with the University of Alaska Fairbanks (UAF), TDX was able to identify suitable technologies and demonstrate their applicability in the rural Alaskan environment. TDX and UAF partnered to engage and educate the entire community of Saint Paul – fom school children to elders – through presentation of research, findings, demonstrations, first hand operation of alternative fuel vehicles.

Isolation and Cultivation of Anaerobes

DEFF Research Database (Denmark)

Aragao Börner, Rosa

2016-01-01

Anaerobic microorganisms play important roles in different biotechnological processes. Their complex metabolism and special cultivation requirements have led to less isolated representatives in comparison to their aerobic counterparts.In view of that, the isolation and cultivation of anaerobic...

Mycoplasma contamination of Chlamydia pneumoniae isolates

DEFF Research Database (Denmark)

Huniche, BS; Jensen, Lise Torp; Birkelund, Svend

1998-01-01

media, immunoblotting, polymerase chain reaction and pulsed field gel electrophoresis. Two of the 6 ATCC isolates [ATCC VR1355 (TWAR strain 2043) and ATCC VR1356 (TWAR strain 2023)] were infected with Mycoplasma hominis and 1 isolate [ATCC VR2282 (TWAR strain TW183)] was contaminated with both...... Mycoplasma hominis and Mycoplasma orale, whereas 3 of the ATCC isolates [ATCC VR1310, ATCC VR1360 (TWAR strain CM-1) and ATCC 53592 (TWAR strain AR39)] were not contaminated. The Finnish C. pneumoniae isolates Kajaani 6 and Parola were found to be contaminated with M. hominis and M. orale, respectively...

Permanent isolation surface barrier: Functional performance

International Nuclear Information System (INIS)

Wing, N.R.

1993-10-01

This document presents the functional performance parameters for permanent isolation surface barriers. Permanent isolation surface barriers have been proposed for use at the Hanford Site (and elsewhere) to isolate and dispose of certain types of waste in place. Much of the waste that would be disposed of using in-place isolation techniques is located in subsurface structures, such as solid waste burial grounds, tanks, vaults, and cribs. Unless protected in some way, the wastes could be transported to the accessible environment via transport pathways, such as water infiltration, biointrusion, wind and water erosion, human interference, and/or gaseous release

Fault Isolation for Shipboard Decision Support

DEFF Research Database (Denmark)

Lajic, Zoran; Blanke, Mogens; Nielsen, Ulrik Dam

2010-01-01

Fault detection and fault isolation for in-service decision support systems for marine surface vehicles will be presented in this paper. The stochastic wave elevation and the associated ship responses are modeled in the frequency domain. The paper takes as an example fault isolation of a containe......Fault detection and fault isolation for in-service decision support systems for marine surface vehicles will be presented in this paper. The stochastic wave elevation and the associated ship responses are modeled in the frequency domain. The paper takes as an example fault isolation...... to the quality of decisions given to navigators....

Analysis of CDM Projects' Portfolio in West African Economic and Monetary Union - Regional Baseline Assessment in Energy Sector. Case Study: Benin, Burkina Faso, Niger and Togo

OpenAIRE

Satoguina, Honorat

2006-01-01

This study analyses current energy projects in Benin, Burkina Faso, Niger and Togo. Based on the size of these projects, the study shows that currently, only small scale CDM projects can be developed in these countries in energy sectors. Moreover, baseline emissions factors are assessed for the different electricity grids. These baselines are very low in interconnected grids in cities, while they are relatively high for isolated and non-connected utilities in remote areas. Consequently, count...

Exe-Guard Project

Energy Technology Data Exchange (ETDEWEB)

Smith, Rhett [Schweitzer Engineering Lab., Inc., Pullman, WA (United States); Marshall, Tim [Dominion Virginia Power, Richmond, VA (United States); Chavez, Adrian [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Bratus, Sergey [Dartmouth College, Hanover, NH (United States)

2016-01-30

compromised. This project provided non-destructive intrusion, isolation and automated response solution, achieving a goal of the Department of Energy (DOE) Roadmap to Secure Control Systems. It also addressed CIP-007-R4 which requires asset owners to employ malicious software prevention tools on assets within the electronic security perimeter. In addition, the CIP-007-R3 requirement for security patch management is minimized because white listing narrows the impact of vulnerabilities and patch releases. The exe-Guard Project completed all tasks identified in the statement of project objective and identified additional tasks within scope that were performed and completed within the original budget. The cost share was met and all deliverables were successfully completed and submitted on time. Most importantly the technology developed and commercialized under this project has been adopted by the Energy sector and thousands of devices with exe-Guard technology integrated in them have now been deployed and are protecting our power systems today

Construction quality assurance program plan for the WIPP project, Carlsbad, NM

International Nuclear Information System (INIS)

1987-05-01

The purpose of this plan is to describe the Quality Assurance (QA) Program to be established and implemented by the US Department of Energy (DOE) Waste Isolation Pilot Plant (WIPP) Project Office (WPO) and by the Major Project Participants: the Architect-Engineer (Bechtel), the Construction Manager (US Army Corps of Engineers), the Scientific Advisor (Sandia National Laboratory), and the Management and Operating Contractor (Westinghouse Electric Corporation). This plan addresses the construction, including site evaluation, design, and turnover phases of WIPP. Other work in progress during the same period is controlled by DOE documents applicable to that work effort. The prime responsibility for ensuring the quality of construction rests with the DOE WIPP Project Office and is implemented through the combined efforts of the Construction Manager, the Construction Contractors, the Management and Operating Contractor, and the Architect-Engineer. Inspection and burden of proof of acceptability rests with the Construction Contractor as defined by the technical provisions of the contract and as otherwise specified by the DOE WIPP Project Office on an individual work-package basis. To the maximum extent possible, acceptance of work will be based upon first-hand witnessing by the Construction Manager and other representatives of the DOE organization

Seismic isolation systems designed with distinct multiple frequencies

International Nuclear Information System (INIS)

Wu, Ting-shu; Seidensticker, R.W.

1991-01-01

Two systems for seismic base isolation are presented. The main feature of these system is that, instead of only one isolation frequency as in conventional isolation systems, they are designed to have two distinct isolation frequencies. When the responses during an earthquake exceed the design value(s), the system will automatically and passively shift to the secondly isolation frequency. Responses of these two systems to different ground motions including a harmonic motion with frequency same as the primary isolation frequency, show that no excessive amplification will occur. Adoption of these new systems certainly will greatly enhance the safety and reliability of an isolated superstructure against future strong earthquakes. 3 refs

Patterns of reproductive isolation in the Drosophila subquinaria complex: can reinforced premating isolation cascade to other species?

Science.gov (United States)

Humphreys, Devon P.; Rundle, Howard D.; Dyer, Kelly A.

2016-01-01

Abstract The reinforcement of premating barriers due to reduced hybrid fitness in sympatry may cause secondary sexual isolation within a species as a by-product. Consistent with this, in the fly Drosophila subquinaria, females that are sympatric with D. recens mate at very low rates not only with D. recens, but also with conspecific D. subquinaria males from allopatry. Here, we ask if these effects of reinforcement cascade more broadly to affect sexual isolation with other closely related species. We assay reproductive isolation of these species with D. transversa and find that choosy D. subquinaria females from the region sympatric with D. recens discriminate strongly against male D. transversa, whereas D. subquinaria from the allopatric region do not. This increased sexual isolation cannot be explained by natural selection to avoid mating with this species, as they are allopatric in geographic range and we do not identify any intrinsic postzygotic isolation between D. subquinaria and D. transversa. Variation in epicuticular hydrocarbons, which are used as mating signals in D. subquinaria, follow patterns of premating isolation: D. transversa and allopatric D. subquinaria are most similar to each other and differ from sympatric D. subquinaria, and those of D. recens are distinct from the other two species. We suggest that the secondary effects of reinforcement may cascade to strengthen reproductive isolation with other species that were not a target of selection. These effects may enhance the divergence that occurs in allopatry to help explain why some species are already sexually isolated upon secondary contact. PMID:29491905

Managing project complexity : A study into adapting early project phases to improve project performance in large engineering projects

NARCIS (Netherlands)

Bosch-Rekveldt, M.G.C.

2011-01-01

Engineering projects become increasingly more complex and project complexity is assumed to be one of the causes for projects being delivered late and over budget. However, what this project complexity actually comprised of was unclear. To improve the overall project performance, this study focuses

Isolation of Pasteurella multocida subspec. Multocida from chronic periapical lesion: First isolation in ex-Yugoslavia

Directory of Open Access Journals (Sweden)

Suvajdžić Ljiljana Ð.

2006-01-01

Full Text Available This study presents five isolates of Pasteurella multocida subsp. multo-cida isolated from chronic periapical inflammatory lesion. We described the methods of sampling and cultivation as well as diagnostic criteria. Pasteurella multocida was diagnosed on the basis of characteristic cultural and tinctorial properties and the facts that all strains produced indole and induced ornithine decarboxilation, glucose, saccharose and manitole fermentation. Isolates produced neither urease, nor fermented lactose and maltose. Further classification to subspecies multocida was based on the fact that all investigated isolates fermented trechalose, xylose and sorbitol the traits which are diagnostically significant for the species. Patients deny any contact with farm animals or pets, which indicates a possible aerosol transport and animal-human as well as human-human infection. We consider that this organism should be paid more attention by dentist, oral surgeons and microbiologists.

Final Technical Report - Kotzebue Wind Power Project - Volume II

Energy Technology Data Exchange (ETDEWEB)

Rana Zucchi, Global Energy Concepts, LLC; Brad Reeve, Kotzebue Electric Association; DOE Project Officer - Doug Hooker

2007-10-31

The Kotzebue Wind Power Project is a joint undertaking of the U.S. Department of Energy (DOE); Kotzebue Electric Association (KEA); and the Alaska Energy Authority (AEA). The goal of the project is to develop, construct, and operate a wind power plant interconnected to a small isolated utility grid in an arctic climate in Northwest Alaska. The primary objective of KEA’s wind energy program is to bring more affordable electricity and jobs to remote Alaskan communities. DOE funding has allowed KEA to develop a multi-faceted approach to meet these objectives that includes wind project planning and development, technology transfer, and community outreach. The first wind turbines were installed in the summer of 1997 and the newest turbines were installed in the spring of 2007. The total installed capacity of the KEA wind power project is 1.16 MW with a total of 17 turbines rated between 65 kW and 100 kW. The operation of the wind power plant has resulted in a wind penetration on the utility system in excess of 35% during periods of low loads. This document and referenced attachments are presented as the final technical report for the U.S. Department of Energy (DOE) grant agreement DE-FG36-97GO10199. Interim deliverables previously submitted are also referenced within this document and where reasonable to do so, specific sections are incorporated in the report or attached as appendices.

Three-dimensional trace measurements for fast-moving objects using binary-encoded fringe projection techniques.

Science.gov (United States)

Su, Wei-Hung; Kuo, Cho-Yo; Kao, Fu-Jen

2014-08-20

A fringe projection technique to trace the shape of a fast-moving object is proposed. A binary-encoded fringe pattern is illuminated by a strobe lamp and then projected onto the moving object at a sequence of time. Phases of the projected fringes obtained from the sequent measurements are extracted by the Fourier transform method. Unwrapping is then performed with reference to the binary-encoded fringe pattern. Even though the inspected object is colorful, fringe orders can be identified. A stream of profiles is therefore retrieved from the sequent unwrapped phases. This makes it possible to analyze physical properties of the dynamic objects. Advantages of the binary-encoded fringe pattern for phase unwrapping also include (1) reliable performance for colorful objects, spatially isolated objects, and surfaces with large depth discontinuities; (2) unwrapped errors only confined in a local area; and (3) low computation cost.

Design experience on seismically isolated buildings

International Nuclear Information System (INIS)

Giuliani, G.C.

1989-01-01

This paper describes the practical problems associated with the structural design of a group of seismically isolated buildings now under construction in Ancona, Italy. These structures are the first seismically isolated buildings in Italy. Taking into account previous earthquakes, the structural design of these new buildings was performed according to an acceleration spectrum which was different from its Zone 2 seismic code and which provided protection for stronger ground motions. To minimize the cost of the structure, the buildings used ribbed plate decks, thus reducing the amount of material and the mass of the structures to be isolated. The design requirements, dynamic analysis performed, structural design, and practical engineering employed are reported in this paper. A comparison between the costs of a conventionally designed and a base-isolated structure is also reported. The tests undertaken for certifying the mechanical properties of the isolators for both static and dynamic loads are also described, as is the full-scale dynamic test which is scheduled for next year (1990) for one of the completed buildings. Lessons learned in this design effort are potentially applicable to seismic base isolation for nuclear power plants

A half mode inkjet printed tunable ferrite isolator

KAUST Repository

Ghaffar, Farhan A.

2017-10-24

A novel half mode waveguide based ferrite isolator design is presented in this work. For the first time, tunability of the isolation band is demonstrated for a ferrite isolator. Instead of using the conventional antisymmetric bias the isolator requires a single direction of the magnetic bias field due to the half mode operation. Yttrium Iron Garnet (YIG) is used as the substrate for the device. The metallic walls of the waveguide are realized using inkjet printing. The magnetic biasing applied to the waveguide causes the RF waves to experience negative permeability in one direction of propagation hence providing isolation for this direction. For an applied bias of 3000 Oe, the device provides a maximum isolation figure of merit of 76.7 dB at 7.5 GHz. The isolation band can be controlled by changing the applied magnetostatic bias. As the bias is varied from 1500 Oe to 3500 Oe the center frequency of the isolation band varies from 4.45 GHz to 9 GHz. The measured response of the isolator shows that it can be integrated in any RF system requiring lower cost and good isolation.

Oligotrophic bacteria isolated from clinical materials.

OpenAIRE

Tada, Y; Ihmori, M; Yamaguchi, J

1995-01-01

Oligotrophic bacteria (oligotrophs) are microorganisms that grow in extremely nutritionally deficient conditions in which the concentrations of organic substances are low. Many oligotrophic bacteria were isolated from clinical materials including urine, sputum, swabbings of the throat, vaginal discharges, and others. Seventy-seven strains of oligotrophic bacteria from 871 samples of clinical material were isolated. A relatively higher frequency of isolation of oligotrophic bacteria was shown ...

Filamentous fungi isolated from grape marc as antagonists of Botrytis cinerea

Directory of Open Access Journals (Sweden)

Jovičić-Petrović Jelena P.

2016-01-01

Full Text Available In this paper we report on the isolation and identification of three filamentous fungi from grape marc, and antifungal effect of their cell-free culture filtrates on the growth of Botrytis cinerea, causal agent of gray mold. Grape marc is a waste material that has been used as soil amendment in sustainable agriculture. Isolates originating from grape marc were identified on the basis of morphological features and internal transcribed spacer rDNA or β-tubulin gene sequencing. The presence of three different species, Penicillium paneum, Penicillium chrysogenum and Aspergillus fumigatus has been detected expressing different effect on the growth of B. cinerea. The effect of crude culture filtrates of selected fungi on B. cinerea growth was tested. Heat sensitivity of the established inhibition effect was examined by autoclaving the crude culture filtrate prior to testing. Additional aim was to determine whether antifungal effect was influenced by previous exposure to B. cinerea in dual liquid cultures. Crude culture filtrate of A. fumigatus K16/2 showed the lowest suppression of B. cinerea growth. A maximal percentage inhibition achieved within the study was 38.2%, 39.8% and 23.8 for crude filtrates of P. paneum K7/1, P. chrysogenum K11/1 and A. fumigatus K16/2, respectively. Presence of B. cinerea in dual liquid culture induced significant increase in antifungal capacity of the culture filtrates in comparison to pure culture filtrates of the chosen isolates. The antifungal activity of all of the isolates’ culture filtrates retained after heat treatment suggesting the presence of some thermostable antifungal metabolites. The results indicate the complexity and specificity of the interaction between filamentous fungi and B. cinerea. Grape marc is a good source for isolation od B. cinerea fungal antagonists and their antifungal metabolites. Specificity of fungal-fungal interactions suggests that further research on the antagonistic mechanisms and

The processing of the acai in a project 'Model for Electric Power Enterprise in Isolated Communities in the Amazon' - NERAM; O beneficiamento do acai no projeto Modelo de Negocio de Energia Eletrica em Comunidades Isoladas na Amazonia - NERAM

Energy Technology Data Exchange (ETDEWEB)

Xavier, Diogo J.C.; Souza, Rubem C.R.; Seye, Omar; Bacellar, Atlas A.; Santos, Eyde C.S.; Freitas, Katriana T.; Rodrigues, Monica; Morais, Marcia R.; Guimaraes, Euler L. [Universidade Federal do Amazonas (CDEAM/UFAM), Manaus, AM (Brazil). Centro de Desenvolvimento Energetico Amazonico], Emails: diogo_am@yahoo.com.br, cdeam@ufam.edu.br

2006-07-01

This article presents a discussion on the productive processes associated with the acai within the project 'Model for Electric Power Enterprise in Isolated Communities in the Amazon - NERAM', financed by the National Council for Scientific and Technological Development - CNPq. With the premise of global use of the fruit of the acai trees, all the stages of the processing are described. These stages comprise the extraction of the pulp, treatment of residues, drying of the acai seeds, and it use for power generation. Estimates of the proportions are described in mass of the fruit involved in the stages of the processes, from the pulp extraction till the final products, and characteristics of the generation equipment. (author)

Spent Nuclear Fuel project, project management plan

International Nuclear Information System (INIS)

Fuquay, B.J.

1995-01-01

The Hanford Spent Nuclear Fuel Project has been established to safely store spent nuclear fuel at the Hanford Site. This Project Management Plan sets forth the management basis for the Spent Nuclear Fuel Project. The plan applies to all fabrication and construction projects, operation of the Spent Nuclear Fuel Project facilities, and necessary engineering and management functions within the scope of the project

Managing projects using a project management approach

Directory of Open Access Journals (Sweden)

Marko D. Andrejić

2011-04-01

Full Text Available Modern management theory treats all complex tasks and duties like projects and make these projects possible to be managed by a particular organizational-management concept in order to achieve a goal effectively. A large number of jobs and tasks performed in the system of defense or for defense purposes have the characteristics of projects. Project management is both a skill and a science of monitoring human, material, financial, energy and other resources to achieve required objectives within the given limits: deadlines, time, budget, possibility of realization and the satisfaction of the interests of all project participants. Project management is a traditional area of applied (or functional management focused on managing complex and uncertain situations with defined goals. Introduction In conditions of rapid change and high uncertainty, only adaptive organizations survive, i. e. those that are able not only to react quickly to changes but also to proactively take advantage of changes. Development of project management The biggest influence on the development of the area had complex jobs within the engineering profession. In parallel with the traditional approach new approaches began to develop, while the traditional one still remained in use. Contrary to the traditional engineering approach, a dynamic model first developed in order to respond to demands for greater control of costs. Project management Project management is a skill and knowledge of human and material resources to achieve set objectives within prescribed limits: deadlines, time, budget, possibility of realization, and the satisfaction of all participants in the project. In order to realize a project effectively, it is necessary to manage it rationally. Planning and project management A project plan is a document that allows all team members insight on where to go, when to start and when to arrive, what is necessary to be done in order to achieve the project objectives and what

EMPLACEMENT DRIFT ISOLATION DOOR CONTROL SYSTEM

International Nuclear Information System (INIS)

N.T. Raczka

1998-01-01

The purpose of this analysis is to review and refine key design concepts related to the control system presently under consideration for remotely operating the emplacement drift isolation doors at the potential subsurface nuclear waste repository at Yucca Mountain. This analysis will discuss the key design concepts of the control system that may be utilized for remotely monitoring, opening, and closing the emplacement drift isolation doors. The scope and primary objectives of this analysis are to: (1) Discuss the purpose and function of the isolation doors (Presented in Section 7.1). (2) Review the construction of the isolation door and other physical characteristics of the doors that the control system will interface with (Presented in Section 7.2). (3) Discuss monitoring and controlling the operation of the isolation doors with a digital control system (either a Programmable Logic Controller (PLC) system or a Distributed Control System (DCS)) (Presented in Section 7.3). (4) Discuss how all isolation doors can be monitored and controlled from a subsurface central control center (Presented in Section 7.4). This analysis will focus on the development of input/output (I/O) counts including the types of I/O, redundancy and fault tolerance considerations, and processor requirements for the isolation door control system. Attention will be placed on operability, maintainability, and reliability issues for the system operating in the subsurface environment with exposure to high temperatures and radiation

Chemical analyses of potash-bearing horizons from 21 exploratory holes drilled at a tentative site for the Waste Isolation Pilot Plant, Eddy County, New Mexico

International Nuclear Information System (INIS)

Griswold, G.B.

1977-09-01

Sandia Laboratories drilled 21 potash drill holes over an 18,960-acre site in east-central Eddy County, New Mexico, to evaluate potash resources as part of their Waste Isolation Pilot Plant (WIPP) project. This report furnishes assay information on samples obtained from the drilling program

Isolation Effect in Immediate and Delayed Recall

Science.gov (United States)

Bellezza, Francis S.; Cheney, Terry L.

1973-01-01

If the hypothesis of selective rehearsal is used to account for the isolation effect, then the recall of isolated items will depend both on the serial position of the isolated item and on whether recall is immediate or delayed. (Author)

Problem Drug Use, Marijuana, and European Projects: How Epidemiology Helped Czech Policy Reformers

OpenAIRE

Jan Morávek

2008-01-01

I examine the transfer of the Problem Drug Use (PDU) concept into Czech scientific discourse through European institutions’ projects, and view PDU’s utilization by Czech researchers in relation to marijuana decriminalization efforts.PDU is defined as intravenous and/or long-term and regular use of opiates, cocaine, or amphetamines. Out of a vast array of illicit drug use patterns, this concept isolates a relatively small population with the riskiest use patterns to become the focus of public ...

Geomorphology of Minnesota - Isolated Landform Structures

Data.gov (United States)

Minnesota Department of Natural Resources — Geomorphology of Minnesota - Isolated Landform Structures are essentially cartographic arcs representing isolated glacial features that were mapped in conjunction...

METHICILLIN RESISTANCE IN STAPHYLOCOCCAL ISOLATES ...

African Journals Online (AJOL)

The study assessed the importance of Staphylococcus aureus as a urinary pathogen and the incidence of multidrug resistant (MDR), methicillin-resistant Staphylococcus aureus (MRSA). A total of 86 staphylococcal isolates made up of 50 clinical isolates from urine samples submitted to the Medical Microbiology Laboratory ...

Dielectric isolation for power integrated circuits; Isolation dielectrique enterree pour les circuits integres de puissance

Energy Technology Data Exchange (ETDEWEB)

Zerrouk, D.

1997-07-18

Considerable efforts have been recently directed towards integrating onto the same chip, sense or protection elements that is low voltage analog and/or digital control circuitry together with high voltage/high current devices. Most of these so called `smart power` devices use either self isolation, junction isolation or Silicon-On-Insulator (SOI) to integrate low voltage elements with vertical power devices. Dielectric isolation is superior to the other isolation techniques such as self isolation or junction isolation. Thesis work consists of the study of the feasibility of a dielectric technology based on the melting and the solidification in a Rapid Thermal Processing furnace (RTP), of thick polysilicon films deposited on oxide. The purpose of this technique is to obtain substrate with localized SOI structures for smart power applications. SOI technology offers significant potential advantages, such as non-occurrence of latch-up in CMOS structures, high packaging density, low parasitic capacitance and the possibility of 3D structures. In addition, SOI technology using thick silicon films (10-100 {mu}m) offers special advantages for high voltage integrated circuits. Several techniques have been developed to form SOI films. Zone melting recrystallization is one of the most promising for localized SOI. The SOI structures have first been analyzed in term of extended defects. N-channel MOSFET`s transistors have also been fabricated in the SOI substrates and electrically characterized (threshold voltages, off-state leakage current, mobilities,...). The SOI transistors exhibit good characteristics, although inferior to witness transistors. The recrystallized silicon films are therefore found to be suitable for the fabrication of SOI devices. (author) 106 refs.

Comparison of Brachyspira hyodysenteriae Isolates Recovered from Pigs in Apparently Healthy Multiplier Herds with Isolates from Herds with Swine Dysentery.

Directory of Open Access Journals (Sweden)

Tom La

Full Text Available Swine dysentery (SD is a mucohaemorrhagic colitis of grower/finisher pigs classically resulting from infection by the anaerobic intestinal spirochaete Brachyspira hyodysenteriae. This study aimed to determine whether B. hyodysenteriae isolates from pigs in three healthy German multiplier herds supplying gilts to other farms differed from isolates from nine German production herds with SD. Isolates were subjected to whole genomic sequencing, and in silico multilocus sequence typing showed that those from the three multiplier herds were of previously undescribed sequence types (ST132, ST133 and ST134, with all isolates from the same herd having the same ST. All isolates were examined for the presence of 332 genes encoding predicted virulence or virulence lifestyle associated factors, and these were well conserved. Isolates from one multiplier herd were atypical in being weakly haemolytic: they had 10 amino acid substitutions in the haemolysin III protein and five in the haemolysin activation protein compared to reference strain WA1, and had a disruption in the promoter site of the hlyA gene. These changes likely contribute to the weakly haemolytic phenotype and putative lack of virulence. These same isolates also had nine base pair insertions in the iron metabolism genes bitB and bitC and lacked five of six plasmid genes that previously have been associated with colonisation. Other overall differences between isolates from the different herds were in genes from three of five outer membrane proteins, which were not found in all the isolates, and in members of a block of six plasmid genes. Isolates from three herds with SD had all six plasmid genes, while isolates lacking some of these genes were found in the three healthy herds-but also in isolates from six herds with SD. Other differences in genes of unknown function or in gene expression may contribute to variation in virulence; alternatively, superior husbandry and better general health may have

Isolation of rat adrenocortical mitochondria

Energy Technology Data Exchange (ETDEWEB)

Solinas, Paola [Department of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 (United States); Department of Medicine, Center for Mitochondrial Disease, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 (United States); Fujioka, Hisashi [Electron Microscopy Facility, Department of Pharmacology, Center for Mitochondrial Disease, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 (United States); Tandler, Bernard [Department of Biological Sciences, School of Dental Medicine, Center for Mitochondrial Disease, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 (United States); Hoppel, Charles L., E-mail: charles.hoppel@case.edu [Department of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 (United States); Department of Medicine, Center for Mitochondrial Disease, School of Medicine, Case Western Reserve University, Cleveland, OH 44106 (United States)

2012-10-12

Highlights: Black-Right-Pointing-Pointer A method for isolation of adrenocortical mitochondria from the adrenal gland of rats is described. Black-Right-Pointing-Pointer The purified isolated mitochondria show excellent morphological integrity. Black-Right-Pointing-Pointer The properties of oxidative phosphorylation are excellent. Black-Right-Pointing-Pointer The method increases the opportunity of direct analysis of adrenal mitochondria from small animals. -- Abstract: This report describes a relatively simple and reliable method for isolating adrenocortical mitochondria from rats in good, reasonably pure yield. These organelles, which heretofore have been unobtainable in isolated form from small laboratory animals, are now readily accessible. A high degree of mitochondrial purity is shown by the electron micrographs, as well as the structural integrity of each mitochondrion. That these organelles have retained their functional integrity is shown by their high respiratory control ratios. In general, the biochemical performance of these adrenal cortical mitochondria closely mirrors that of typical hepatic or cardiac mitochondria.

Seismic Isolation Studies and Applications for Nuclear Facilities

International Nuclear Information System (INIS)

Choun, Young Sun

2005-01-01

Seismic isolation, which is being used worldwide for buildings, is a well-known technology to protect structures from destructive earthquakes. In spite of the many potential advantages of a seismic isolation, however, the applications of a seismic isolation to nuclear facilities have been very limited because of a lack of sufficient knowledge about the isolation practices. The most important advantage of seismic isolation applications in nuclear power plants is that the safety and reliability of the plants can be remarkably improved through the standardization of the structures and equipment regardless of the seismic conditions of the sites. The standardization of structures and equipment will reduce the capital cost and design/construction schedule for future plants. Also, a seismic isolation can facilitate decoupling of the design and development for equipment, piping, and components due to the use of the generic in-structure response spectra associated with the standardized plant. Moreover, a seismic isolation will improve the plant safety margin against the design basis earthquake (DBE) as well as a beyond design basis seismic event due to its superior seismic performance. A number of seismic isolation systems have been developed and tested since 1970s, and some of them have been applied to conventional structures in several countries of high seismicity. In the nuclear field, there have been many studies on the applicability of such seismic isolation systems, but the application of a seismic isolation is very limited. Currently, there are some discussions on the application of seismic isolation systems to nuclear facilities between the nuclear industries and the regulatory agencies in the U.S.. In the future, a seismic isolation for nuclear facilities will be one of the important issues in the nuclear industry. This paper summarizes the past studies and applications of a seismic isolation in the nuclear industry

Isolated Horizon, Killing Horizon and Event Horizon

OpenAIRE

Date, G.

2001-01-01

We consider space-times which in addition to admitting an isolated horizon also admit Killing horizons with or without an event horizon. We show that an isolated horizon is a Killing horizon provided either (1) it admits a stationary neighbourhood or (2) it admits a neighbourhood with two independent, commuting Killing vectors. A Killing horizon is always an isolated horizon. For the case when an event horizon is definable, all conceivable relative locations of isolated horizon and event hori...

Calculation of projected waste loads for transuranic waste management alternatives

International Nuclear Information System (INIS)

Hong, K.; Kotek, T.; Koebnick, B.; Wang, Y.; Kaicher, C.

1995-01-01

The level of treatment and the treatment and interim storage site configurations (decentralized, regional, or centralized) impact transuranic (TRU) waste loads at and en route to sites in the US Department of Energy (DOE) complex. Other elements that impact waste loads are the volume and characteristics of the waste and the unit operation parameters of the technologies used to treat it. Projected annual complexwide TRU waste loads under various TRU waste management alternatives were calculated using the WASTEunderscoreMGMT computational model. WASTEunderscoreMGMT accepts as input three types of data: (1) the waste stream inventory volume, mass, and contaminant characteristics by generating site and waste stream category; (2) unit operation parameters of treatment technologies; and (3) waste management alternative definitions. Results indicate that the designed capacity of the Waste Isolation Pilot Plant, identified under all waste management alternatives as the permanent disposal facility for DOE-generated TRU waste, is sufficient for the projected complexwide TRU waste load under any of the alternatives

Project management of life-science research projects: project characteristics, challenges and training needs.

Science.gov (United States)

Beukers, Margot W

2011-02-01

Thirty-four project managers of life-science research projects were interviewed to investigate the characteristics of their projects, the challenges they faced and their training requirements. A set of ten discriminating parameters were identified based on four project categories: contract research, development, discovery and call-based projects--projects set up to address research questions defined in a call for proposals. The major challenges these project managers are faced with relate to project members, leadership without authority and a lack of commitment from the respective organization. Two-thirds of the project managers indicated that they would be interested in receiving additional training, mostly on people-oriented, soft skills. The training programs that are currently on offer, however, do not meet their needs. Copyright © 2010 Elsevier Ltd. All rights reserved.

NSR&D Program Fiscal Year (FY) 2015 Call for Proposals Mitigation of Seismic Risk at Nuclear Facilities using Seismic Isolation

Energy Technology Data Exchange (ETDEWEB)

Coleman, Justin [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2015-02-01

Seismic isolation (SI) has the potential to drastically reduce seismic response of structures, systems, or components (SSCs) and therefore the risk associated with large seismic events (large seismic event could be defined as the design basis earthquake (DBE) and/or the beyond design basis earthquake (BDBE) depending on the site location). This would correspond to a potential increase in nuclear safety by minimizing the structural response and thus minimizing the risk of material release during large seismic events that have uncertainty associated with their magnitude and frequency. The national consensus standard America Society of Civil Engineers (ASCE) Standard 4, Seismic Analysis of Safety Related Nuclear Structures recently incorporated language and commentary for seismically isolating a large light water reactor or similar large nuclear structure. Some potential benefits of SI are: 1) substantially decoupling the SSC from the earthquake hazard thus decreasing risk of material release during large earthquakes, 2) cost savings for the facility and/or equipment, and 3) applicability to both nuclear (current and next generation) and high hazard non-nuclear facilities. Issue: To date no one has evaluated how the benefit of seismic risk reduction reduces cost to construct a nuclear facility. Objective: Use seismic probabilistic risk assessment (SPRA) to evaluate the reduction in seismic risk and estimate potential cost savings of seismic isolation of a generic nuclear facility. This project would leverage ongoing Idaho National Laboratory (INL) activities that are developing advanced (SPRA) methods using Nonlinear Soil-Structure Interaction (NLSSI) analysis. Technical Approach: The proposed study is intended to obtain an estimate on the reduction in seismic risk and construction cost that might be achieved by seismically isolating a nuclear facility. The nuclear facility is a representative pressurized water reactor building nuclear power plant (NPP) structure

Comparison of the isolation rates and characteristics of Salmonella isolated from antibiotic-free and conventional chicken meat samples.

Science.gov (United States)

Park, J-H; Kim, H-S; Yim, J-H; Kim, Y-J; Kim, D-H; Chon, J-W; Kim, H; Om, A-S; Seo, K-H

2017-08-01

Salmonella contamination in chicken samples can cause major health problems in humans. However, not only the effects of antibiotic treatment during growth but also the impacts of the poultry slaughter line on the prevalence of Salmonellae in final chicken meat sold to consumers are unknown. In this study, we compared the isolation rates and antimicrobial resistance of Salmonellae among antibiotic-free, conventional, conventional Korean native retail chicken meat samples, and clonal divergence of Salmonella isolates by multilocus sequence typing. In addition, the distribution of extended-spectrum β-lactamase (ESBL) genes in ESBL-producing Salmonella isolates was analyzed. A total of 72 retail chicken meat samples (n = 24 antibiotic-free broiler [AFB] chickens, n = 24 conventional broiler [CB] chickens, and n = 24 conventional Korean native [CK] chickens) was collected from local retail markets in Seoul, South Korea. The isolation rates of Salmonellae were 66.6% in AFB chickens, 45.8% in CB chickens, and 25% in CK chickens. By analyzing the minimum inhibitory concentrations of β-lactam antibiotics with the disc-diffusion test, we found that 81.2% of Salmonella isolates from AFB chickens, 63.6% of isolates from CB chickens, and 50% of isolates from CK chickens were ESBL producers; all ESBL-positive isolates had the CTX-M-15 genotype. Interestingly, all ESBL-producing Salmonellae were revealed as ST16 by multilocus sequence typing and had the genetic platform of blaCTX-M gene (IS26-ISEcp1-blaCTX-M-15-IS903), which was first reported in Salmonellae around the world. The Salmonella ST33 strain (S. Hadar) isolated in this study has never been reported in South Korea. In conclusion, our findings showed that antibiotic-free retail chicken meat products were also largely contaminated with ESBL-producing Salmonellae and that their ESBL genes and genetic platforms were the same as those isolated from conventional retail chicken meat products. © 2017 Poultry Science

Chromosome Isolation by Flow Sorting in Aegilops umbellulata and Ae. comosa and Their Allotetraploid Hybrids Ae. biuncialis and Ae. geniculata

Czech Academy of Sciences Publication Activity Database

Molnár, I.; Kubaláková, Marie; Šimková, Hana; Cseh, A.; Molnár-Láng, M.; Doležel, Jaroslav

2011-01-01

Roč. 66, č. 11 (2011), s. 1-11 E-ISSN 1932-6203 R&D Projects: GA MŠk(CZ) LC06004; GA MŠk OC08025 Grant - others:European Regional Development Fund CZ.1.05/2.1.00/ 01.0007 Institutional research plan: CEZ:AV0Z50380511 Keywords : wheat * chromosome isolation * Aegilops umbellulata Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.092, year: 2011

K-Basin isolation barrier seal

International Nuclear Information System (INIS)

Ruff, E.S.

1994-10-01

This report documents various aspects of the design, analysis, procurement, and fabrication of the hydraulic seal on the isolation barriers to be installed in the 100-K Area spent nuclear fuel basin. The isolation barrier is used to keep water in the basin in the event of an earthquake

Geographically isolated wetlands: Rethinking a misnomer

Science.gov (United States)

Mushet, David M.; Calhoun, Aram J.K.; Alexander, Laurie C.; Cohen, Matthew J.; DeKeyser, Edward S.; Fowler, Laurie G.; Lane, Charles R.; Lang, Megan W.; Rains, Mark C.; Walls, Susan

2015-01-01

We explore the category “geographically isolated wetlands” (GIWs; i.e., wetlands completely surrounded by uplands at the local scale) as used in the wetland sciences. As currently used, the GIW category (1) hampers scientific efforts by obscuring important hydrological and ecological differences among multiple wetland functional types, (2) aggregates wetlands in a manner not reflective of regulatory and management information needs, (3) implies wetlands so described are in some way “isolated,” an often incorrect implication, (4) is inconsistent with more broadly used and accepted concepts of “geographic isolation,” and (5) has injected unnecessary confusion into scientific investigations and discussions. Instead, we suggest other wetland classification systems offer more informative alternatives. For example, hydrogeomorphic (HGM) classes based on well-established scientific definitions account for wetland functional diversity thereby facilitating explorations into questions of connectivity without an a priori designation of “isolation.” Additionally, an HGM-type approach could be used in combination with terms reflective of current regulatory or policymaking needs. For those rare cases in which the condition of being surrounded by uplands is the relevant distinguishing characteristic, use of terminology that does not unnecessarily imply isolation (e.g., “upland embedded wetlands”) would help alleviate much confusion caused by the “geographically isolated wetlands” misnomer.

Behavioural reproductive isolation and speciation in Drosophila

Indian Academy of Sciences (India)

In the genus Drosophila, the phenomenon of behavioural reproductive isolation, which is an important type of premating (prezygotic) reproductive isolating mechanisms, has been extensively studied and interesting data have been documented. In many cases incomplete sexual isolation has been observed and the pattern ...

Isolation and morphological characterization of antibiotic producing ...

African Journals Online (AJOL)

Purpose: To isolate and characterize antibiotic producing actinomycetes from soil samples in Belgaum, Karnataka, India. Methods: Crowded plate technique was used for the isolation of actinomycetes in media such as soybean – casein digest medium and actinomycetes isolation agar. The morphological and cultural ...

Isolation, screening and identification of novel isolates of Actinomycetes from India for antimicrobial applications

Directory of Open Access Journals (Sweden)

Vineeta Singh

2016-12-01

Full Text Available The search for novel bioactive compounds from the natural environment has been rapidly increased with the increase in multi-drug resistant (MDR pathogens. In the present study, the antimicrobial potential of novel actinomycetes has been evaluated by initial screening of six soil samples. Primary and secondary screening was performed against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Candida albicans, Candida tropicalis, Trichophyton rubrum, and other MDR bacterial and fungal test strains, and at the end thirteen active isolates were selected for further study. Microbial strains were identified on the basis of growth conditions and other biochemical characters. Five most active microbial strains were identified using 16S rRNA sequence homology and designated as Streptomyces xanthophaeus MTCC 11938, Streptomyces variabilis MTCC 12266, Streptomyces xanthochromogenes MTCC 11937, Streptomyces levis EU 124569 and Streptomyces sp. NCIM 5500. Four antibacterial and three antifungal compounds isolated from the above five isolates were purified and partially characterized using UV absorption and IR spectra. Two antibacterial metabolites, belong to chromone and peptide antibiotic, respectively. The antifungal compounds were found to be of non-polyene nature. In conclusion, we study the isolation of novel bacterial strains of actinomycetes for producing novel compounds having antibacterial and antifungal activities from the unexplored agro-ecological niches of India. Also, this study paves the way for further characterization of these isolates of Streptomyces sp. for their optimum utilization for antimicrobial purposes.

Isolation and Identification of L-asparaginase producing Erwinia strains which isolated from Potato Farms

Directory of Open Access Journals (Sweden)

Arastoo Badoei-Dalfard

2016-09-01

Full Text Available Introduction: L-Asparaginase can be effectively used for the treatment of lymphoblastic leukemia. The rapid growth of cancer cells are needed for L-asparagine abundant storage. L-asparaginase catalyzes the hydrolysis of L-asparagine into L-aspartic acid and ammonia. The purpose of this study was to isolate and identify the L-asparaginase producing Erwinia strains from the potato farms of Jiroft. Materials and methods: Pectolytic Erwinia species isolated from crumbling potato in M9 medium. The desired L-asparaginase producing bacteria were isolated based on the color changes. Biochemical-microbial and the plant pathogenicity tests of these strains were also investigated with potato and geranium. The L-asparaginase production and molecular detection of these Erwinia strains were also investigated. Results: In this study, L-asparaginase producing Erwinia was isolated on the CVP and M9 mediums. The inoculation of Erwinia strains on the potato and geranium plants showed that Er8 and Er11 species have the ability to cause plant pathogenicity. Results showed that the maximum pathogenicity of Er8 and Er11 was observed after 48 and 15 h of inoculation in potato and geranium plants, respectively. 16S rDNA sequencing and phylogenetic analyses exhibited that Er8 and Er11 strains were similar to Erwinia chrysanthemi with 98% homology. Discussion and conclusion: Because of several applications of the Erwinia L-asparaginase in various fields, isolated Erwinia and their L-asparaginase can be suitable for applied utilization.

The isolation and purification of a caribbean maitotoxin

Energy Technology Data Exchange (ETDEWEB)

Davis, S.E.; Knoepp, S.M.; Lanoue, B.A. [and others

1994-12-31

The phenomenon known as red tide has been a topic of great interest in that there is concern that the scale and complexity of this natural phenomenon are expanding. It is known that the benthic dinoflagellate, Gambierdiscus toxicus, produces a variety of polyether toxins that contaminate seafood and result in human illness. Maitotoxin (MTX) is one of the toxins that have been implicated in ciguatera seafood poisoning. There is a need for the development of a much broader understanding of the nature of the poisoning toxins. MTX cogeners can be difficult to isolate due to its size and chemical nature. A major goal is to obtain a purified standard of a Caribbean MTX so that more efficient assays can be developed to test seafood for the presence of toxins and thus avoid human harm. The primary goal of this project is to obtain large amounts of pure maitotoxin. The procedure described is also useful as a starting point for the purification of other toxins.

Blending mining and nuclear industries at the Waste Isolation Pilot Plant

International Nuclear Information System (INIS)

Walls, J.R.

1990-01-01

At the Waste Isolation Pilot Plant (WIPP) traditional procedures for underground mining activities have been significantly altered in order to assure underground safety and project adherence to numerous regulatory requirements. Innovative techniques have been developed for WIPP underground procedures, mining equipment, and operating environments. The mining emphasis at WIPP is upon the quality of the excavation, not (as in conventional mines) on the production of ore. The WIPP is a United States Department of Energy (DOE) project that is located 30 miles southeast of Carlsbad, New Mexico, where the nation's first underground engineered nuclear repository is being constructed. The WIPP site was selected because of its location amidst a 607 meter thick salt bed, which provides a remarkably stable rock formation for the permanent storage of nuclear waste. The underground facility is located 655 meters below the earth's surface, in the Salado formation, which comprises two-hundred million year old halites with minor amounts of clay and anhydrites. When completed, the WIPP underground facility will consist of two components: approximately 81 square kilometers of experimental areas, and approximately 405 square kilometers of repository. 3 figs

Verification and improvement of analytical modeling of seismic isolation bearings and isolated structures

International Nuclear Information System (INIS)

Forni, M.; La Grotteria, M.; Martelli, A.; Bertola, S.; Bettinali, F.; Dusi, A.; Bergamo, G.; Bonacina, G.

2002-01-01

Due to the complexity of dynamic behaviour of seismic isolation (SI) devices, high cost of their tests and non-negligible number of devices having excellent potential for nuclear applications, several countries judged of great interest to extend validation of their numerical models of such devices to the analysis of experimental data obtained by others. Thus, a four-years Coordinated Research Program (CRP) on Intercomparison of Analysis Methods for Isolated Nuclear Structures, proposed by ENEA (1995), was endorsed by the IAEA in 1995. There, Italy was jointly represented by ENEA, ENEL and ISMES, and supplied test results concerning both High Damping Rubber Bearings (HDRBs) and the MISS (Model of Isolated Steel Structure) mock-up, which had been isolated using such bearings. Test data provided by Italy to the other countries were also re-analysed to improve mathematical models. Aim of this final report is to summarise, after a brief description of the devices and structures considered, the most important results and conclusions of the numerical analyses carried out by Italy. For more detailed information, especially as far as the execution of the tests and the implementation of the numerical models are concerned, please refer to the technical reports presented by Italy to the Research Coordination Meetings (RCMs). (author)

Final Scientific/Technical Report for "Nanite" for Better Well-Bore Integrity and Zonal Isolation

Energy Technology Data Exchange (ETDEWEB)

Veedu, Vinod [Oceanit Laboratories, Inc., Honolulu, HI (United States); Hadmack, Michael [Oceanit Laboratories, Inc., Honolulu, HI (United States); Pollock, Jacob [Oceanit Laboratories, Inc., Honolulu, HI (United States); Pernambuco-Wise, Paul [Oceanit Laboratories, Inc., Honolulu, HI (United States); Ah Yo, Derek [Oceanit Laboratories, Inc., Honolulu, HI (United States)

2017-05-30

Nanite™ is a cementitious material that contains a proprietary formulation of functionalized nanomaterial additive to transform conventional cement into a smart material responsive to pressure (or stress), temperature, and any intrinsic changes in composition. This project has identified optimal sensing modalities of smart well cement and demonstrated how real-time sensing of Nanite™ can improve long-term wellbore integrity and zonal isolation in shale gas and applicable oil and gas operations. Oceanit has explored Nanite’s electrical sensing properties in depth and has advanced the technology from laboratory proof-of-concept to sub-scale testing in preparation for field trials.

Isolation and antibiotic resistance of Ureaplasma spp. isolated from urogenital specimen between 2002 to 2007

Directory of Open Access Journals (Sweden)

Tito Del Gaudio

2009-03-01

Full Text Available Ureaplasma spp. and Mycoplasma hominis are frequently isolated from urogenital samples. Ureaplasma spp is responsible for cervicovaginitis, salpingitis, urethritis, epididymitis, male and female infertility, spontaneous abortion, and during pregnancy, for the premature rupture of the membranes, because of chorionamnionitis. Our study aimed to establish the pattern of antimicrobial resistance among Ureaplasma spp isolated in the area of Andria,Apulia Region, from January 2002 to December 2007. 240/781 (30.7% of the urogenital samples examined were found Ureaplasma spp.-positive. 152/240 (63.3 % were >104 UFC/ml and 88/240 (36.7 % were <104 UFC/ml. With regard to the resistance rate, we observed significant increase in resistance to ciprofloxacin, ofloxacin, erythromycin, clarithromycin, and azithromycin. While we did not observe resistance to doxycycline, strains resistant to tetracycline, josamycin, and pristinamycins, were isolated during last years of investigation. Our data may help improve the management of these infections above all in consideration of the differences among isolates in different geographic regions.

Security Isolation Strategy Mechanism for Lightweight Virtualization Environment

Directory of Open Access Journals (Sweden)

Liu Qian

2017-01-01

Full Text Available For cloud service providers, lightweight virtualization is a more economical way of virtualization. While the user is worried about the safety of applications and data of the container, due to the container sharing the underlying interface and the kernel, therefore the security and trusted degree of lightweight virtualization container isolation mechanism is critical for the promotion of lightweight virtualization service. Because the user cannot directly participate in the process of the construction and management of container isolation mechanism, it is difficult for them to establish confidence in the security and trusted degree of container isolation mechanism. Based on the research and analysis of system credible and virtualization isolation mechanism, this paper puts forward a set of lightweight virtualization security isolation strategy mechanism, divides lightweight virtualization container storage address space into several parts, puts forward the definition of lightweight virtualization security isolation, gives the formal description and proof of container security isolation strategy, and combines with related technology to verify the feasibility of lightweight virtualization security isolation strategy mechanism. The mechanism has important guiding significance for cloud services providers to deploy container security isolation.

Isolation and Characterization of Aerobic Actinomycetes from Soil in Northern Iran and Evaluation of their Antimicrobial Potential

Directory of Open Access Journals (Sweden)

Esmaeil Emami

2017-10-01

Full Text Available Background:   Aerobic actinomycetes can be detected in soil, worldwide. But, their diversity can differ depending on ecological and environmental factors including, temperature, humidity and vegetation, etc. The aim of this study was antimicrobial activities of aerobic actinomycetes Isolated from soil in Northern Iran.Methods:   Fifty soil samples throughout Northern Iran provinces, including Guilan, Mazandran and Golestan, have been collected and cultured in selective medium, Starch Casein Agar (SCA. In the first step, isolates were assayed by pointing inoculation in solid medium, agar spot, for antimicrobial activity. Then, for antibiotic production, International Streptomyces Projects 2 (ISP2 and Glucose Yeast Extract Malt extract (GYM media by submerge technique were used. Well diffusion agar method was used for detection of antimicrobial activity and antibiotic sensitivity, and finally metabolites of most active specious detected by GC/MS and GC techniques.Results:   In this study eighty strains were isolated from soil samples. In primary screening, 12 strains (15% recognized as active actinomycetes, among them strain SA3 showed the highest antimicrobial potential. In the secondary screening in the liquid ISP2 medium, 3 (25% isolates (SA7, SA3, SA16 and in GYM medium 7 (58.33% isolates (SA28, SA27, SA7, SA26, SA16, SA2, SA3 have shown the highest antimicrobial potentials; also it was found that there is a significant relation between humidity and pH of soil with the number of isolated colonies. According to results of primary and secondary screening, strains SA3 and SA7 were selected as active actinomycetes and biochemical test revealed that these two active strains isolates belong to the genus Streptomyces. Finally, produced metabolites by strain SA3 were analyzed by GC/MS and GC methods and Oleic acid was revealed as the highest peak.Conclusion:   The findings of the present research show that actinomycetes from Northern Iran

Utilities/industries joint study on seismic isolation systems for LWR: Part I. Experimental and analytical studies on seismic isolation systems

International Nuclear Information System (INIS)

Kato, Muneaki; Sato, Shoji; Shimomura, Issei

1989-01-01

This paper describes a joint study program on seismic isolation systems for light-water reactors (LWRs) performed by ten electric power companies, three manufacturers, and five construction companies. The fundamental response characteristics of base-isolated structures and base-isolation devices are described. Applications of a base-isolation system to LWR buildings are given. Finally, three-dimensional shaking table experiments are described

Permanent isolation surface barrier development plan

International Nuclear Information System (INIS)

Wing, N.R.

1994-01-01

The exhumation and treatment of wastes may not always be the preferred alternative in the remediation of a waste site. In-place disposal alternatives, under certain circumstances, may be the most desirable alternatives to use in the protection of human health and the environment. The implementation of an in-place disposal alternative will likely require some type of protective covering that will provide long-term isolation of the wastes from the accessible environment. Even if the wastes are exhumed and treated, a long-term barrier may still be needed to adequately dispose of the treated wastes or any remaining waste residuals. Currently, no open-quotes provenclose quotes long-term barrier is available. The Hanford Site Permanent Isolation Surface Barrier Development Program (BDP) was organized to develop the technology needed to provide a long-term surface barrier capability for the Hanford Site. The permanent isolation barrier technology also could be used at other sites. Permanent isolation barriers use engineered layers of natural materials to create an integrated structure with redundant protective features. Drawings of conceptual permanent isolation surface barriers are shown. The natural construction materials (e.g., fine soil, sand, gravel, riprap, asphalt) have been selected to optimize barrier performance and longevity. The objective of current designs is to use natural materials to develop a maintenance-free permanent isolation surface barrier that isolates wastes for a minimum of 1,000 years by limiting water drainage to near-zero amounts; reducing the likelihood of plant, animal, and human intrusion; controlling the exhalation of noxious gases; and minimizing erosion-related problems

Permanent isolation surface barrier development plan

Energy Technology Data Exchange (ETDEWEB)

Wing, N.R.

1994-01-01

The exhumation and treatment of wastes may not always be the preferred alternative in the remediation of a waste site. In-place disposal alternatives, under certain circumstances, may be the most desirable alternatives to use in the protection of human health and the environment. The implementation of an in-place disposal alternative will likely require some type of protective covering that will provide long-term isolation of the wastes from the accessible environment. Even if the wastes are exhumed and treated, a long-term barrier may still be needed to adequately dispose of the treated wastes or any remaining waste residuals. Currently, no {open_quotes}proven{close_quotes} long-term barrier is available. The Hanford Site Permanent Isolation Surface Barrier Development Program (BDP) was organized to develop the technology needed to provide a long-term surface barrier capability for the Hanford Site. The permanent isolation barrier technology also could be used at other sites. Permanent isolation barriers use engineered layers of natural materials to create an integrated structure with redundant protective features. Drawings of conceptual permanent isolation surface barriers are shown. The natural construction materials (e.g., fine soil, sand, gravel, riprap, asphalt) have been selected to optimize barrier performance and longevity. The objective of current designs is to use natural materials to develop a maintenance-free permanent isolation surface barrier that isolates wastes for a minimum of 1,000 years by limiting water drainage to near-zero amounts; reducing the likelihood of plant, animal, and human intrusion; controlling the exhalation of noxious gases; and minimizing erosion-related problems.

Dirofilaria immitis JYD-34 isolate: whole genome analysis

Directory of Open Access Journals (Sweden)

Catherine Bourguinat

2017-11-01

Full Text Available Abstract Background Macrocyclic lactone (ML anthelmintics are used for chemoprophylaxis for heartworm infection in dogs and cats. Cases of dogs becoming infected with heartworms, despite apparent compliance to recommended chemoprophylaxis with approved preventives, has led to such cases being considered as suspected lack of efficacy (LOE. Recently, microfilariae collected from a small number of LOE isolates were used as a source of infection of new host dogs and confirmed to have reduced susceptibility to ML in controlled efficacy studies using L3 challenge in dogs. A specific Dirofilaria immitis laboratory isolate named JYD-34 has also been confirmed to have less than 100% susceptibility to ML-based preventives. For preventive claims against heartworm disease, evidence of 100% efficacy is required by FDA-CVM. It was therefore of interest to determine whether JYD-34 has a genetic profile similar to other documented LOE and confirmed reduced susceptibility isolates or has a genetic profile similar to known ML-susceptible isolates. Methods In this study, the 90Mbp whole genome of the JYD-34 strain was sequenced. This genome was compared using bioinformatics tools to pooled whole genomes of four well-characterized susceptible D. immitis populations, one susceptible Missouri laboratory isolate, as well as the pooled whole genomes of four LOE D. immitis populations. Fixation indexes (FST, which allow the genetic structure of each population (isolate to be compared at the level of single nucleotide polymorphisms (SNP across the genome, have been calculated. Forty-one previously reported SNP, that appeared to differentiate between susceptible and LOE and confirmed reduced susceptibility isolates, were also investigated in the JYD-34 isolate. Results The FST analysis, and the analysis of the 41 SNP that appeared to differentiate reduced susceptibility from fully susceptible isolates, confirmed that the JYD-34 isolate has a genome similar to previously