WorldWideScience

Sample records for irradiator js-6500 analisis

  1. Dose distribution, using homogeneous material before the reload of the JS-6500 irradiator

    International Nuclear Information System (INIS)

    Carrasco A, H.

    1991-10-01

    The objective of this report is to determine the dose distribution inside the aluminum containers used for the industrial irradiation, as well as to locate the positions of maximum and minimum doses, before the reloading of the JS-6500 Irradiator. (Author)

  2. Dosimetry of the JS-6500 industrial irradiator for the irradiation of the PVC graduated flasks; Dosimetria del irradiador industrial JS-6500 para la irradiacion de probetas de PVC

    Energy Technology Data Exchange (ETDEWEB)

    Castaneda F, A.; Carrasco A, H.; Martinez P, M.E. [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    2002-07-01

    The dosimetry of the JS-6500 AECL irradiator was realized, outside of the industrial transportation rails to know the dose distribution, as well as its dose speed. This one with the intention of exposing to gamma radiation; plastified PVC graduated flasks and evaluating their interweavement or degradation or both. This study of dosimetry was carried out by means of a theoretical and experimental evaluation in air atmosphere. The results allow to know the irradiation conditions of the PVC graduated flasks as well as those results prove that has not a significant difference among the obtained result as theoretical as experimentally due to that the obtained result in the theoretical evaluation is 2.62 KGy/h and the result for the case of the experimental evaluation is 2.74 KGy/h. (Author)

  3. Dosimetry of the JS-6500 industrial irradiator for the irradiation of the PVC graduated flasks

    International Nuclear Information System (INIS)

    Castaneda F, A.; Carrasco A, H.; Martinez P, M.E.

    2002-01-01

    The dosimetry of the JS-6500 AECL irradiator was realized, outside of the industrial transportation rails to know the dose distribution, as well as its dose speed. This one with the intention of exposing to gamma radiation; plastified PVC graduated flasks and evaluating their interweavement or degradation or both. This study of dosimetry was carried out by means of a theoretical and experimental evaluation in air atmosphere. The results allow to know the irradiation conditions of the PVC graduated flasks as well as those results prove that has not a significant difference among the obtained result as theoretical as experimentally due to that the obtained result in the theoretical evaluation is 2.62 KGy/h and the result for the case of the experimental evaluation is 2.74 KGy/h. (Author)

  4. Reload of cobalt 60 for the J S-6500 irradiator; Recarga de cobalto 60 para el irradiador JS-6500

    Energy Technology Data Exchange (ETDEWEB)

    Torres C, G; Mayoral G, V M

    1991-01-15

    The present work has the purpose to describe the activities of the reloads program of the industrial irradiator J S-6500, elaborated for satisfying part of the demand of services and as a first step, to guide the decision making by the part of the ININ authorities in front of a wide market of this service. (Author)

  5. Statistical analysis of the irradiation process of various products in the industrial irradiator JS-6500; Analisis estadistico del proceso de irradiacion de productos varios en el irradiador industrial JS-6500

    Energy Technology Data Exchange (ETDEWEB)

    Naquid G, C [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

    2003-07-01

    In this work the methodology for the control of the irradiation service applied to disposable products of medical use, foods, medications, cosmetics and several to different dose in the Gamma Irradiation Plant, with radiation of Cobalt 60, by means of the Graphs of Quality Control by Variables. These they are used to check if the irradiation process has been carried out appropriately, or well, if the variations surpass the established limits in the one that influences some another factor. (Author)

  6. Reload of cobalt 60 for the J S-6500 irradiator

    International Nuclear Information System (INIS)

    Torres C, G.; Mayoral G, V.M.

    1991-01-01

    The present work has the purpose to describe the activities of the reloads program of the industrial irradiator J S-6500, elaborated for satisfying part of the demand of services and as a first step, to guide the decision making by the part of the ININ authorities in front of a wide market of this service. (Author)

  7. Statistical analysis of the irradiation process of various products in the industrial irradiator JS-6500

    International Nuclear Information System (INIS)

    Naquid G, C.

    2003-01-01

    In this work the methodology for the control of the irradiation service applied to disposable products of medical use, foods, medications, cosmetics and several to different dose in the Gamma Irradiation Plant, with radiation of Cobalt 60, by means of the Graphs of Quality Control by Variables. These they are used to check if the irradiation process has been carried out appropriately, or well, if the variations surpass the established limits in the one that influences some another factor. (Author)

  8. The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation.

    Science.gov (United States)

    Heckler, Max; Osterberg, Nadja; Guenzle, Jessica; Thiede-Stan, Nina Kristin; Reichardt, Wilfried; Weidensteiner, Claudia; Saavedra, Joseph E; Weyerbrock, Astrid

    2017-06-01

    As a potent radiosensitizer nitric oxide (NO) may be a putative adjuvant in the treatment of malignant gliomas which are known for their radio- and chemoresistance. The NO donor prodrug JS-K (O2-(2.4-dinitrophenyl) 1-[(4-ethoxycarbonyl) piperazin-1-yl] diazen-1-ium-1,2-diolate) allows cell-type specific intracellular NO release via enzymatic activation by glutathione-S-transferases overexpressed in glioblastoma multiforme. The cytotoxic and radiosensitizing efficacy of JS-K was assessed in U87 glioma cells in vitro focusing on cell proliferation, induction of DNA damage, and cell death. In vivo efficacy of JS-K and repetitive irradiation were investigated in an orthotopic U87 xenograft model in mice. For the first time, we could show that JS-K acts as a potent cytotoxic and radiosensitizing agent in U87 cells in vitro. This dose- and time-dependent effect is due to an enhanced induction of DNA double-strand breaks leading to mitotic catastrophe as the dominant form of cell death. However, this potent cytotoxic and radiosensitizing effect could not be confirmed in an intracranial U87 xenograft model, possibly due to insufficient delivery into the brain. Although NO donor treatment was well tolerated, neither a retardation of tumor growth nor an extended survival could be observed after JS-K and/or radiotherapy.

  9. Characterization Problem (Troubleshooting) for IR219 Irradiator, JS10000 in Mintec-SINAGAMA: The Partnership

    International Nuclear Information System (INIS)

    Shahidan Yob; Nor Ishadi Ismail; Kamarudin Buyong

    2015-01-01

    Control of the fuel-efficient plant operations are key to gamma irradiation service in MINTec-Sinagama. Without an efficient operation, irradiation services will be disrupted and lead to customer product failed to be completed in a set time. Additionally, downtime each time operation is also important to monitor to ensure that the fuel-efficient plant exceeded 85% in each month. In this paper MINTec plant operations data collection-Sinagama made during the year 2011-2015. Analysis carried out against downtime, the extent of damage and the action according to the classification of plant problems. This data collection is important for pattern characterization solution that can be made to the irradiator IR219, JS10000 in MINTec-Sinagama. (author)

  10. Design of device for testing in the gamma irradiator

    International Nuclear Information System (INIS)

    Mariano H, E.

    1991-02-01

    In eves of the recharge of the Gamma Irradiator, JS-6500 it was detected, that there was contamination in the container that housed the pencils of Co-60, coming from Argentina, country to which the ININ buys it recharges. It was determined that the contamination in the container was it interns and after discussing several solution options it was determined to manufacture a device to make a washing of the pencils. It was touch to the Management of Radiological Safety to determine the conceptual design of the device to make the washing and the way of operation of the same one. The Management of Prototypes and Models was responsibility of the mechanical design and its production. (Author)

  11. The maintenance and the radiological safety in gamma irradiation facilities

    International Nuclear Information System (INIS)

    Torres C, G.

    1991-01-01

    Presently work the outstanding aspects of the operation and maintenance of the Industrial Irradiator JS 6500 are described that the ININ operates, in the Nuclear Center of Salazar, Estado de Mexico and its relationship with the radiological security for the occupationally exposed personnel. The signal devices are described and of control of the associate teams, as the system of cooling of the source; the plant of treatment of water of the pool and the system of extraction of ozone. On the other hand the procedures are mentioned for the sure operation and the application of the annual programs of maintenance, in their aspects of more interest, to reduce to the maximum the correction of faults, during the routine operation

  12. RootJS: Node.js Bindings for ROOT 6

    Science.gov (United States)

    Beffart, Theo; Früh, Maximilian; Haas, Christoph; Rajgopal, Sachin; Schwabe, Jonas; Wolff, Christoph; Szuba, Marek

    2017-10-01

    We present rootJS, an interface making it possible to seamlessly integrate ROOT 6 into applications written for Node.js, the JavaScript runtime platform increasingly commonly used to create high-performance Web applications. ROOT features can be called both directly from Node.js code and by JIT-compiling C++ macros. All rootJS methods are invoked asynchronously and support callback functions, allowing non-blocking operation of Node.js applications using them. Last but not least, our bindings have been designed to platform-independent and should therefore work on all systems supporting both ROOT 6 and Node.js. Thanks to rootJS it is now possible to create ROOT-aware Web applications taking full advantage of the high performance and extensive capabilities of Node.js. Examples include platforms for the quality assurance of acquired, reconstructed or simulated data, book-keeping and e-log systems, and even Web browser-based data visualisation and analysis.

  13. 21 CFR 880.6500 - Medical ultraviolet air purifier.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Medical ultraviolet air purifier. 880.6500 Section 880.6500 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... to ultraviolet radiation. (b) Classification. Class II (performance standards). ...

  14. Design of device for testing in the gamma irradiator; Diseno de dispositivo para pruebas en el irradiador gamma

    Energy Technology Data Exchange (ETDEWEB)

    Mariano H, E

    1991-02-15

    In eves of the recharge of the Gamma Irradiator, JS-6500 it was detected, that there was contamination in the container that housed the pencils of Co-60, coming from Argentina, country to which the ININ buys it recharges. It was determined that the contamination in the container was it interns and after discussing several solution options it was determined to manufacture a device to make a washing of the pencils. It was touch to the Management of Radiological Safety to determine the conceptual design of the device to make the washing and the way of operation of the same one. The Management of Prototypes and Models was responsibility of the mechanical design and its production. (Author)

  15. jsGraph and jsNMR—Advanced Scientific Charting

    Directory of Open Access Journals (Sweden)

    Norman Pellet

    2014-09-01

    Full Text Available The jsGraph library is a versatile javascript library that allows advanced charting to be rendered interactively in web browsers without relying on server-side image processing. jsGraph is released under the MIT license and is free of charge. While being highly customizable through an intuitive javascript API, jsGraph is optimized to render a large quantity of data in a short amount of time. jsGraphs can display line, scatter, contour or zone series. Examples can be consulted on the project home page [1]. Customization of the chart, its axis and its series is achieved through simple but comprehensive JSON configurations.

  16. Professional AngularJS

    CERN Document Server

    Karpov, Valeri

    2015-01-01

    A comprehensive guide to AngularJS, Google's open-source client-side framework for app development. Most of the existing guides to AngularJS struggle to provide simple and understandable explanations for more advanced concepts. As a result, some developers who understand all the basic concepts of AngularJS struggle when it comes to building more complex real-world applications. Professional AngularJS provides a thorough understanding of AngularJS, covering everything from basic concepts, such as directives and data binding, to more advanced concepts like transclusion, build systems, and auto

  17. The maintenance and the radiological safety in gamma irradiation facilities; El mantenimiento y la seguridad radiologica en instalaciones de irradiacion gamma

    Energy Technology Data Exchange (ETDEWEB)

    Torres C, G [Gerencia de Servicios Tecnicos Nucleares ININ (Mexico)

    1991-07-01

    Presently work the outstanding aspects of the operation and maintenance of the Industrial Irradiator JS 6500 are described that the ININ operates, in the Nuclear Center of Salazar, Estado de Mexico and its relationship with the radiological security for the occupationally exposed personnel. The signal devices are described and of control of the associate teams, as the system of cooling of the source; the plant of treatment of water of the pool and the system of extraction of ozone. On the other hand the procedures are mentioned for the sure operation and the application of the annual programs of maintenance, in their aspects of more interest, to reduce to the maximum the correction of faults, during the routine operation.

  18. Cytoscape tools for the web age: D3.js and Cytoscape.js exporters

    OpenAIRE

    Ono, Keiichiro; Demchak, Barry; Ideker, Trey

    2014-01-01

    In this paper we present new data export modules for Cytoscape 3 that can generate network files for Cytoscape.js and D3.js. Cytoscape.js exporter is implemented as a core feature of Cytoscape 3, and D3.js exporter is available as a Cytoscape 3 app. These modules enable users to seamlessly export network and table data sets generated in Cytoscape to popular JavaScript library readable formats. In addition, we implemented template web applications for browser-based interactive network visualiz...

  19. Express.js blueprints

    CERN Document Server

    Augarten, Ben; Lin, Eric; Shaikh, Aidha; Soriani, Fabiano Pereira; Tisserand, Geoffrey; Zhang, Chiqing; Zhang, Kan

    2015-01-01

    This book is for beginners to Node.js and also for those who are technically advanced. By the end of this book, every competent developer will have achieved expertise in building web applications with Express.js.

  20. Vue.js 2 cookbook build modern, interactive web applications with Vue.js

    CERN Document Server

    Passaglia, Andrea

    2017-01-01

    Vue.js is an open source JavaScript library for building modern, interactive web applications. With a rapidly growing community and a strong ecosystem, Vue.js makes developing complex single page applications a breeze. Its component-based approach, intuitive API, blazing fast core, and compact size make Vue.js a great solution to craft your next front-end application. From basic to advanced recipes, this book arms you with practical solutions to common tasks when building an application using Vue. We start off by exploring the fundamentals of Vue.js: its reactivity system, data-binding syntax, and component-based architecture through practical examples. After that, we delve into integrating Webpack and Babel to enhance your development workflow using single file components. Finally, we take an in-depth look at Vuex for state management and Vue Router to route in your single page applications, and integrate a variety of technologies ranging from Node.js to Electron, and Socket.io to Firebase and HorizonDB. ...

  1. SymJS

    DEFF Research Database (Denmark)

    Andreasen, Esben; Li, Guodong; Ghosh, Indradeep

    2014-01-01

    We present SymJS, a comprehensive framework for automatic testing of client-side JavaScript Web applications. The tool contains a symbolic execution engine for JavaScript, and an automatic event explorer for Web pages. Without any user intervention, SymJS can automatically discover and explore Web...... events, symbolically execute the associated JavaScript code, refine the execution based on dynamic feedbacks, and produce test cases with high coverage. The symbolic engine contains a symbolic virtual machine, a string-numeric solver, and a symbolic executable DOM model. SymJS’s innovations include...... a novel symbolic virtual machine for JavaScript Web, symbolic+dynamic feedback directed event space exploration, and dynamic taint analysis for enhancing event sequence construction. We illustrate the effectiveness of SymJS on standard JavaScript benchmarks and various real-life Web applications...

  2. Ext JS 4 First Look

    CERN Document Server

    Groner, Loiane

    2012-01-01

    This book is a practical step-by-step tutorial which guides you to migrate from Ext JS 3 to Ext JS 4. There are examples backed with explanations and plenty of code and illustrations to look forward to. This book is written for web developers who are familiar with Ext JS 3 and want to have detailed insights into the new features of Ext JS 4.

  3. Mastering Ext JS

    CERN Document Server

    Groner, Loiane

    2013-01-01

    Designed to be a structured guide, Mastering Ext JS is full of engaging examples to help you learn in a practical context.This book is for developers who are familiar with using Ext JS who want to augment their skills to create even better web applications.

  4. Instant typeahead.js

    CERN Document Server

    Osbourn, Toby

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. Instant Typeahead.js is a concise guide with 14 recipes which deals with everything you need to know to become proficient in using this tool and teaches you how to integrate it with other popular projects such as WordPress, Bootstrap, and Ruby on Rails.Instant Typeahead.js is for any web developer who would like to learn more about Typeahead.js in terms of what it can offer and the best ways to achieve common tasks. This book assumes no prior knowledge, but an understanding of JavaS

  5. Data-oriented development with AngularJS

    CERN Document Server

    Waikar, Manoj

    2015-01-01

    This book helps beginner-level AngularJS developers organize AngularJS applications by discussing important AngularJS concepts and best practices. If you are an experienced AngularJS developer but haven't written directives or haven't created custom HTML controls before, then this book is ideal for you.

  6. Instant Zepto.js

    CERN Document Server

    Pointer, Ian

    2013-01-01

    A simple starter guide that will walk you through Zepto.js from installation to more advanced topics using a step-by-step approach with useful examples included along the way.Instant Zepto.js is designed for web developers with some jQuery experience who are interested in speeding up and enhancing their web applications, especially on mobile devices.

  7. Learning Ext JS

    CERN Document Server

    Méndez, Carlos A; Gonzalez, Armando

    2015-01-01

    If you are a JavaScript developer who now wants to use the Ext JS framework, this is the book for you. This guide is useful to you whether you're new to Ext JS 5 or are a seasoned expert. Experience in HTML, CSS, and JavaScript is required in order to understand and get the most out of this book.

  8. Beginning Amazon Web Services with Node.js

    CERN Document Server

    Shackelford, Adam

    2015-01-01

    Beginning Amazon Web Services with Node.js teaches any novice Node.js developer to configure, deploy, and maintain scalable small to large scale Node.js applications in Amazon Web Services. Hosting a Node.js application in a production environment usually means turning to PaaS hosting, but this approach brings problems. Deploying Node.js directly to AWS solves the problems you encounter in these situations, enabling you to cut out the middle man. You will begin with a basic RESTful web service in Node.js, using the popular Express.js framework, pre-built and ready to run in your local env

  9. AngularJS : yksisivuisen web-sovelluksen käyttöliittymän toteutus AngularJS:llä

    OpenAIRE

    Suomijoki, Juha

    2015-01-01

    Opinnäytetyössä tutkittiin mikä on AngularJS-JavaScript-ohjelmistokehys ja miten se soveltuu yksisivuisen web-sovelluksen käyttöliittymän toteutukseen. AngularJS on vuonna 2012 julkaistu Googlen ylläpitämä JavaScript-ohjelmistokehys, joka on tarkoitettu ensisijaisesti yksisivuisten web-sovellusten kehittämiseen. Opinnäytetyön teoriaosuudessa tutkittiin mikä AngularJS on ja mitkä ovat AngularJS:n keskeiset konseptit ja sovelluskomponentit. Tarkastelu pohjautui AngularJS:stä kirjoitettu...

  10. Cytoscape tools for the web age: D3.js and Cytoscape.js exporters.

    Science.gov (United States)

    Ono, Keiichiro; Demchak, Barry; Ideker, Trey

    2014-01-01

    In this paper we present new data export modules for Cytoscape 3 that can generate network files for Cytoscape.js and D3.js. Cytoscape.js exporter is implemented as a core feature of Cytoscape 3, and D3.js exporter is available as a Cytoscape 3 app. These modules enable users to seamlessly export network and table data sets generated in Cytoscape to popular JavaScript library readable formats. In addition, we implemented template web applications for browser-based interactive network visualization that can be used as basis for complex data visualization applications for bioinformatics research. Example web applications created with these tools demonstrate how Cytoscape works in modern data visualization workflows built with traditional desktop tools and emerging web-based technologies. This interactivity enables researchers more flexibility than with static images, thereby greatly improving the quality of insights researchers can gain from them.

  11. Learning Vue.js 2 learn how to build amazing and complex reactive web applications easily with Vue.js

    CERN Document Server

    Filipova, Olga

    2016-01-01

    About This Book Learn how to propagate DOM changes across the website without writing extensive jQuery callbacks code. Learn how to achieve reactivity and easily compose views with Vue.js and understand what it does behind the scenes. Explore the core features of Vue.js with small examples, learn how to build dynamic content into preexisting web applications, and build Vue.js applications from scratch. Who This Book Is For This book is perfect for novice web developer seeking to learn new technologies or frameworks and also for webdev gurus eager to enrich their experience. Whatever your level of expertise, this book is a great introduction to the wonderful world of reactive web apps. What You Will Learn Build a fully functioning reactive web application in Vue.js from scratch. The importance of the MVVM architecture and how Vue.js compares with other frameworks such as Angular.js and React.js. How to bring reactivity to an existing static application using Vue.js. How to use p...

  12. AngularJS Performance: A Survey Study

    OpenAIRE

    Ramos, Miguel; Valente, Marco Tulio; Terra, Ricardo

    2017-01-01

    AngularJS is a popular JavaScript MVC-based framework to construct single-page web applications. In this paper, we report the results of a survey with 95 professional developers about performance issues of AngularJS applications. We report common practices followed by developers to avoid performance problems (e.g., use of third-party or custom components), the general causes of performance problems in AngularJS applications (e.g., inadequate architecture decisions taken by AngularJS users), a...

  13. Instant AngularJS starter

    CERN Document Server

    Menard, Dan

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. This book is written in an easytoread style, with a strong emphasis on realworld, practical examples. Stepbystep explanations are provided for performing important tasks.This book is for web developers familiar with JavascriptIt doesn't cover the history of AngularJS, and it's not a pitch to convince you that AngularJS is the best framework on the entire web. It's a guide to help you learn everything you need to know about AngularJS in as few pa

  14. AngularJS testing cookbook

    CERN Document Server

    Bailey, Simon

    2015-01-01

    This book is intended for developers who have an understanding of the basic principles behind both AngularJS and test-driven development. You, as a developer, are interested in eliminating the fear related to either introducing tests to an existing codebase or starting out testing on a fresh AngularJS application. If you're a team leader or part of a QA team with the responsibility of ensuring full test coverage of an application, then this book is ideal for you to comprehend the full testing scope required by your developers. Whether you're new to or are well versed with AngularJS, this book

  15. Progress in food irradiation: South Africa

    International Nuclear Information System (INIS)

    Linde, H.J. van der

    1978-01-01

    The most significant development to date is the commissioning of a pilot plant for the treatment of subtropical fruits at Tzaneen (N. Transvaal) in January 1977. The purpose of this facility is to generate commercial quantities of treated produce for process and product evaluation. The irradiator consists of a six-metre-deep pool filled with water. The product is lowered in two large, watertight containers which surround the plaque source. To provide for dose homogeneity, the containers are rotated at half the exposure time. With the present loading of cobalt-60, the treatment time for one batch of approximately 350 kg of fruit is approximately one hour. The pilot plant has been successfully used this year to treat approximately 6.5 t of mangoes in the commercial sea-shipment trial, as well as several small consignments of avocados and papayas sent to local markets for evaluation. The existing facilities are the same as described in the previous report. The commercial sterilization plant (AECL JS6500) has been up-graded to 400 kCi of cobalt-60. The research loop in this plant has been utilized to treat 10.5 t of potatoes which were supplied to local supermarkets for trial sale purposes. (orig.) [de

  16. Learning Less.js

    CERN Document Server

    Libby, Alex

    2014-01-01

    If you are a designer or developer who wants to quickly learn how to harness the power of Less.js to write more efficient CSS styles that can be applied to a website of any size, then this book is for you. This book will help you master both the basic functions and advanced features of Less.js. It would be helpful to have some familiarity of writing CSS styles, although no prior experience of using CSS preprocessors is required.

  17. AngularJS test-driven development

    CERN Document Server

    Chaplin, Tim

    2015-01-01

    This book is for developers who want to learn about AngularJS development by applying testing techniques. You are assumed to have a basic knowledge and understanding of HTML, JavaScript, and AngularJS.

  18. 20 CFR 653.106 - JS day-haul responsibilities.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false JS day-haul responsibilities. 653.106 Section... THE EMPLOYMENT SERVICE SYSTEM Services for Migrant and Seasonal Farmworkers (MSFWs) § 653.106 JS day... Regional Administrator is obtained. (b) No JS applicants shall be referred to non-JS operated day-haul...

  19. Ember.js web development with Ember CLI

    CERN Document Server

    Puri, Suchit

    2015-01-01

    If you are a JavaScript developer who is starting out to build ambitious Ember.js application, or a developer who has prior Ember.js experience and want to transition your application to the latest Ember.js version with Ember CLI, then this book is for you.

  20. AngularJS web application development

    CERN Document Server

    Darwin, Peter Bacon

    2013-01-01

    The book will be a step-by-step guide showing the readers how to build a complete web app with AngularJSJavaScript developers who want to learn AngularJS for developing web apps. Knowledge of JavaScript and HTML is expected. No knowledge of AngularJS is required.

  1. Should we be screening for anti-Js(a)?

    Science.gov (United States)

    Nikolis, Nancy M; Boctor, Fouad; Heaton, William Andrew; Martone, James

    2011-01-01

    We analyzed our historic patient database at North Shore University Hospital and determined both the overall frequency of anti-Js(a) and the frequency at which it was detected in combination with other alloantibodies to red blood cell (RBC) antigens. Screening cells used currently are negative for Js(a). Our data suggest that anti-Js(a) would not be detected in 30 to 40 percent of patients in which it is the sole antibody present. Since 1996 the antibody was only detected when other antibodies were found in the screening process. We are exposing 1.7 percent of our patients (90 patients/year) to Js(a). The clinical significance of anti-Js(a) is apparent with previous literature, and our conclusion is that additional studies should be performed to determine whether Js(a) should be included in current antibody screening cells.

  2. 20 CFR 658.421 - Handling of JS-related complaints.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Handling of JS-related complaints. 658.421... ADMINISTRATIVE PROVISIONS GOVERNING THE JOB SERVICE SYSTEM Job Service Complaint System Federal Js Complaint System § 658.421 Handling of JS-related complaints. (a) No JS-related complaint shall be handled at the...

  3. 20 CFR 658.415 - Transferring complaints to proper JS office.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Transferring complaints to proper JS office... Agency Js Complaint System § 658.415 Transferring complaints to proper JS office. (a) Where a JS-related... local office serving the area in which the employer is located. Where a JS-related complaint deals with...

  4. Data visualization with D3 and AngularJS

    CERN Document Server

    Körner, Christoph

    2015-01-01

    If you are a web developer with experience in AngularJS and want to implement interactive visualizations using D3.js, this book is for you. Knowledge of SVG or D3.js will give you an edge to get the most out of this book.

  5. Responsive web design with AngularJS

    CERN Document Server

    Patel, Sandeep Kumar

    2014-01-01

    If you are an AngularJS developer who wants to learn about responsive web application development, this book is ideal for you. Responsive Web Design with AngularJS is intended for web developers or designers with a basic knowledge of HTML, CSS, and JavaScript.

  6. Transforming capacity of two novel genes JS-1 and JS-2 located in chromosome 5p and their overexpression in human esophageal squamous cell carcinoma.

    Science.gov (United States)

    Fatima, Sarwat; Chui, Chung H; Tang, Wing K; Hui, Kin S; Au, Ho W; Li, Wing Y; Wong, Mei M; Cheung, Filly; Tsao, S W; Lam, King Y; Beh, Philip S L; Wong, John; Law, Simon; Srivastava, Gopesh; Ho, Kwok P; Chan, Albert S C; Tang, Johnny C O

    2006-01-01

    Esophageal squamous cell carcinoma (ESCC) has a high mortality rate and geographic differences in incidence. Previous studies of comparative genomic hybridization (CGH) showed that chromosomal 5p is frequently amplified in cell lines and primary ESCC of Hong Kong Chinese origin. In this report, attempt was made to study two novel genes, named as JS-1 and JS-2, which are located in chromosome 5p15.2 and are 5' upstream to delta catenin for their roles in molecular pathogenesis of ESCC. Eleven cell lines, 27 primary ESCC cases and multiple human tissue cDNA panels (MTC) of digestive system were studied for the expression level of JS-1 and JS-2 by RT-PCR. The full-length cDNA sequences of JS-1 and JS-2 were determined from a non-tumor esophageal epithelial cell line by 3' and 5' rapid amplification of cDNA ends (RACE). The transforming capacity of JS-1 and JS-2 was also investigated by transfecting NIH 3T3 cells with the expression vector pcDNA3.1(-) cloned with the full coding sequences and it was followed by the study of foci formation of the transfected cells under confluence growth and the anchorage-independent growth in soft agar. Forty-five percent (5/11) and 18% (2/11) of the ESCC cell lines showed overexpression of JS-1 and JS-2 respectively, while 55% (15/27) and 14% (3/22) primary ESCC cases showed overexpression of JS-1 and JS-2 respectively. JS-1 overexpression was most common in patients with stage II ESCC (6/27; 22%) whereas JS-2 was only overexpressed in a dysplastic lesion (1/22; 4%) and stage III tumors (2/22; 9%). The expression levels of JS-1 and JS-2 are both low in normal esophageal tissues. Overexpression of JS-1 in NIH 3T3 cells caused foci formation in confluence growth and colony formation in soft agar but not for JS-2. A high grade sarcoma was formed in the athymic nude mice when NIH 3T3 cells overexpressing JS-1 were injected subcutaneously. Our results thus indicate that the frequent overexpression of JS-1 in ESCC and its transforming

  7. Practical Ext JS Projects with Gears

    CERN Document Server

    Zammetti, Frank

    2009-01-01

    Discover Ext JS, one of today's most powerful and highly regarded JavaScript frameworks, with perhaps the best set of GUI widgets around, and a whole host of components that make developing client--side applications a breeze. Using a pragmatic approach, you'll dissect seven full--fledged applications, covering *How Ext JS allows you to create these applications with a slick user interface with a minimum of effort*How the other parts of Ext JS aside from the GUI widgets provide many of the capabilities modern applications need, such as Ajax and data mechanisms *How other technologies such as Ge

  8. Connecting YARP to the Web with Yarp.js

    Directory of Open Access Journals (Sweden)

    Carlo Ciliberto

    2017-12-01

    Full Text Available We present yarp.js, a JavaScript framework enabling robotics networks to interface and interact with external devices by exploiting modern Web communication protocols. By connecting a YARP server module with a browser client on any external device, yarp.js allows to access on board sensors using standard Web APIs and stream the acquired data through the yarp.js network without the need for any installation. Communication between YARP modules and yarp.js clients is bi-directional, opening also the possibility for robotics applications to exploit the capabilities of modern browsers to process external data, such as speech synthesis, 3D data visualization, or video streaming to name a few. Yarp.js requires only a browser installed on the client device, allowing for fast and easy deployment of novel applications. The code and sample applications to get started with the proposed framework are available for the community at the yarp.js GitHub repository.

  9. パラオ海溝の深海6500mに存在する石灰岩体の溶解

    OpenAIRE

    坪井, 辰哉; 和田, 秀樹; 中村, 俊夫; 松崎, 浩之; 大辻, 菜穂; 藤岡, 換太郎; 小栗, 一将; 北里, 洋; Tsuboi, Tatsuya; Wada, Hideki; Nakamura, Toshio; Matsuzaki, Hiroyuki; Otsuji, Naho; Fujioka, Kantaro; Oguri, Kazumasa

    2013-01-01

    The large limestone block was found at 6500m depth of Palau Trench in 1993. The Sr isotopic age of this limestone shows the accumulation age of late Miocene. Using the submersible Shinkai 6500, we report the 14C density of seawater collected around the large limestone block on the landward slope of the Palau Trench, at around 6500m depth, which is significantly deeper than the carbonate compensation depth (CCD). AMS-14C measurements of dissolved inorganic carbon (DIC) extracted revealed value...

  10. blastjs: a BLAST+ wrapper for Node.js.

    Science.gov (United States)

    Page, Martin; MacLean, Dan; Schudoma, Christian

    2016-02-27

    To cope with the ever-increasing amount of sequence data generated in the field of genomics, the demand for efficient and fast database searches that drive functional and structural annotation in both large- and small-scale genome projects is on the rise. The tools of the BLAST+ suite are the most widely employed bioinformatic method for these database searches. Recent trends in bioinformatics application development show an increasing number of JavaScript apps that are based on modern frameworks such as Node.js. Until now, there is no way of using database searches with the BLAST+ suite from a Node.js codebase. We developed blastjs, a Node.js library that wraps the search tools of the BLAST+ suite and thus allows to easily add significant functionality to any Node.js-based application. blastjs is a library that allows the incorporation of BLAST+ functionality into bioinformatics applications based on JavaScript and Node.js. The library was designed to be as user-friendly as possible and therefore requires only a minimal amount of code in the client application. The library is freely available under the MIT license at https://github.com/teammaclean/blastjs.

  11. 20 CFR 658.411 - Filing and assignment of JS-related complaints.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Filing and assignment of JS-related... Agency Js Complaint System § 658.411 Filing and assignment of JS-related complaints. (a) JS-related... office personnel shall be as follows: (1) All JS-related complaints filed with a local office, and...

  12. Exposing Library Services with AngularJS

    OpenAIRE

    Jakob Voß; Moritz Horn

    2014-01-01

    This article provides an introduction to the JavaScript framework AngularJS and specific AngularJS modules for accessing library services. It shows how information such as search suggestions, additional links, and availability can be embedded in any website. The ease of reuse may encourage more libraries to expose their services via standard APIs to allow usage in different contexts.

  13. A Quantitative Measure of JS's Memory

    Science.gov (United States)

    Ben Shalom, Dorit; Faran, Yifat; Boucher, Jill

    2010-01-01

    JS is a highly able, well-educated 37 year old man with Asperger syndrome. A recent qualitative paper (Boucher, 2007) described his self-report of verbal and visual memory difficulties. The present paper used the WMS-III to compare the memory profile of JS to that of the adults with HFA in the Williams et al. (2005) WMS-III paper. Results show…

  14. 20 CFR 658.416 - Action on JS-related complaints.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Action on JS-related complaints. 658.416... ADMINISTRATIVE PROVISIONS GOVERNING THE JOB SERVICE SYSTEM Job Service Complaint System State Agency Js Complaint System § 658.416 Action on JS-related complaints. (a) The appropriate State agency official handling an...

  15. 32 CFR 311.7 - OSD/JS Privacy Office Processes.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false OSD/JS Privacy Office Processes. 311.7 Section...) PRIVACY PROGRAM OFFICE OF THE SECRETARY OF DEFENSE AND JOINT STAFF PRIVACY PROGRAM § 311.7 OSD/JS Privacy Office Processes. The OSD/JS Privacy Office shall: (a) Exercise oversight and administrative control of...

  16. Deploying Node.js

    CERN Document Server

    Pasquali, Sandro

    2015-01-01

    If you are an intermediate or advanced developer deploying your Node.js applications, then this book is for you. If you have already built a Node application or module and want to take your knowledge to the next level, this book will help you find your way.

  17. Antifungal activity of the osthol derivative JS-B against Phytophthora capsici.

    Science.gov (United States)

    Wang, Chun-Mei; Guan, Wei; Fang, Shu; Chen, Hao; Li, You-Qin; Cai, Chun; Fan, Yong-Jian; Shi, Zhi-Qi

    2010-08-01

    JS-B (C(12)H(10)O(3)) is a derivative compound of osthol. The antifungal properties of JS-B were tested against 10 economically important plant pathogens. JS-B was effective in inhibiting the mycelial growth of Phytophthora capsici, and its inhibition on different stages of the life cycle of P. capsici was observed. The 50% effective concentration (EC(50)) of JS-B on mycelial dry weight and zoospore germination of P. capsici was 43.74 and 86.03 microg/ml, respectively. The rupture of released zoospores induced by JS-B was reduced by the addition of 100 mM glucose. The ultrastructural study showed that JS-B caused destruction of most of the mitochondrions, the concentration of cell nuclear, and the existing vesicles. When compared with dimethomorph, the activity of JS-B on P. capsici was determined under pot conditions. The result showed that JS-B has a curative effect on pepper blight.

  18. 20 CFR 658.410 - Establishment of State agency JS complaint system.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Establishment of State agency JS complaint... Agency Js Complaint System § 658.410 Establishment of State agency JS complaint system. (a) Each State... State Administrator shall have overall responsibility for the operation of the State agency JS complaint...

  19. Mastering Ext JS

    CERN Document Server

    Groner, Loiane

    2015-01-01

    If you are a developer who is familiar with Ext JS and want to augment your skills to create even better web applications, this is the book for you. Basic knowledge of JavaScript/HTML/CSS and any server-side language (PHP, Java, C#, Ruby, or Python) is required.

  20. KnockoutJS blueprints

    CERN Document Server

    Russo, Carlo

    2015-01-01

    If you are a JavaScript developer and already know the basics of KnockoutJS and you want to get the most out of it, then this book is for you. This book will help in your transition from a small site to a large web application that is easily maintainable.

  1. Altered JS-2 expression in colorectal cancers and its clinical pathological relevance.

    Science.gov (United States)

    Lam, Alfred King-Yin; Gopalan, Vinod; Nassiri, Mohammad Reza; Kasim, Kais; Dissanayake, Jayampathy; Tang, Johnny Chuek-On; Smith, Robert Anthony

    2011-10-01

    JS-2 is a novel gene located at 5p15.2 and originally detected in primary oesophageal cancer. There is no study on the role of JS-2 in colorectal cancer. The aim of this study is to determine the gene copy number and expression of JS-2 in a large cohort of patients with colorectal tumours and correlate these to the clinicopathological features of the cancer patients. We evaluated the DNA copy number and mRNA expression of JS-2 in 176 colorectal tissues (116 adenocarcinomas, 30 adenomas and 30 non-neoplastic tissues) using real-time polymerase chain reaction. JS-2 expression was also evaluated in two colorectal cancer cell lines and a benign colorectal cell line. JS-2 amplification was noted in 35% of the colorectal adenocarcinomas. Significant differences in relative expression levels for JS-2 mRNA between different colorectal tissues were noted (p = 0.05). Distal colorectal adenocarcinoma had significantly higher copy number than proximal adenocarcinoma (p = 0.005). The relative expression level of JS-2 was different between colonic and rectal adenocarcinoma (p = 0.007). Mucinous adenocarcinoma showed higher JS-2 expression than non-mucinous adenocarcinoma (p = 0.02). Early T-stage cancers appear to have higher JS-2 copy number and lower expression of JS-2 mRNA than later stage cancers (p = 0.001 and 0.03 respectively). Colorectal cancer cell lines showed lower expression of JS-2 than the benign colorectal cell line. JS-2 copy number change and expression were shown for the first time to be altered in the carcinogenesis of colorectal cancer. In addition, genetic alteration of JS-2 was found to be related to location, pathological subtypes and staging of colorectal cancer. Copyright © 2011 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  2. Cytoscape.js: a graph theory library for visualisation and analysis.

    Science.gov (United States)

    Franz, Max; Lopes, Christian T; Huck, Gerardo; Dong, Yue; Sumer, Onur; Bader, Gary D

    2016-01-15

    Cytoscape.js is an open-source JavaScript-based graph library. Its most common use case is as a visualization software component, so it can be used to render interactive graphs in a web browser. It also can be used in a headless manner, useful for graph operations on a server, such as Node.js. Cytoscape.js is implemented in JavaScript. Documentation, downloads and source code are available at http://js.cytoscape.org. gary.bader@utoronto.ca. © The Author 2015. Published by Oxford University Press.

  3. 20 CFR 658.414 - Referral of non-JS-related complaints.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Referral of non-JS-related complaints. 658... ADMINISTRATIVE PROVISIONS GOVERNING THE JOB SERVICE SYSTEM Job Service Complaint System State Agency Js Complaint System § 658.414 Referral of non-JS-related complaints. (a) To facilitate the operation of the...

  4. HTML5 game programming with enchant.js

    CERN Document Server

    Shimizu, Ryo; Fushimi, Ryohei; Tanaka, Ryo; Kratzer, Kevin; McInnis, Brandon; Inc, enchantjs

    2013-01-01

    Official book from the developers of enchant.js. Enchant.js is open source, so there is no barrier for entry. Provides aspiring game developers with a tool to program fully-fledged games quickly and easily. Teaches the basics of HTML5 and JavaScript, invaluable tools for budding programmers. Shares invaluable tips from professional game developers for creating compelling game design and content.

  5. 3Dmol.js: molecular visualization with WebGL.

    Science.gov (United States)

    Rego, Nicholas; Koes, David

    2015-04-15

    3Dmol.js is a modern, object-oriented JavaScript library that uses the latest web technologies to provide interactive, hardware-accelerated three-dimensional representations of molecular data without the need to install browser plugins or Java. 3Dmol.js provides a full featured API for developers as well as a straightforward declarative interface that lets users easily share and embed molecular data in websites. 3Dmol.js is distributed under the permissive BSD open source license. Source code and documentation can be found at http://3Dmol.csb.pitt.edu dkoes@pitt.edu. © The Author 2014. Published by Oxford University Press.

  6. KnockoutJS web development

    CERN Document Server

    Farrar, John

    2015-01-01

    This book is for web developers and designers who work with HTML and JavaScript to help them manage data and interactivity with data using KnockoutJS. Knowledge about jQuery will be useful but is not necessary.

  7. AngularJS yksisivuisen web-applikaation kehitysalustana

    OpenAIRE

    Karhu, Tuomo

    2015-01-01

    Yksisivuiset web-applikaatiot (SPA-sovellukset) ovat yleistyneet viimeisten kymmenen vuoden aikana, ja näiden avulla on ollut mahdollista tuoda verkkosivuston käyttökokemus lähemmäksi aitojen ohjelmasovellusten vastaavaa. Yksisivuisten web-applikaatioitten kehitystyöhön tarkoitetuista sovelluskehyksistä AngularJS on yksi käytetyimmistä ja suosituimmista. Työn tavoitteena on selvittää miten AngularJS-sovelluskehys soveltuu SPA-sivustojen kehitykseen sovelluskehittäjän näkökulmasta, sekä mi...

  8. Gamma irradiation service in Mexico

    International Nuclear Information System (INIS)

    Liceaga C, G.; Martinez A, L.; Mendez T, D.; Ortiz A, G.; Olvera G, R.

    1997-01-01

    In 1980 it was installed in Mexico, on the National Institute of Nuclear Research, an irradiator model J S-6500 of a canadian manufacture. Actually, this is the greatest plant in the Mexican Republic that offers a gamma irradiation process at commercial level to diverse industries. However, seeing that the demand for sterilize those products were not so much as the irradiation capacity it was opted by the incursion in other types of products. During 17 years had been irradiated a great variety of products grouped of the following form: dehydrated foods, disposable products for medical use, cosmetics, medicaments, various. Nowadays the capacity of the irradiator is saturated virtue of it is operated the 24 hours during the 365 days of the year and only its operation is suspended by the preventive and corrective maintenance. However, the fresh food market does not be attended since this irradiator was designed for doses greater than 10 kGy (1.0 Mrad)

  9. Learning Three.js the JavaScript 3D library for WebGL

    CERN Document Server

    Dirksen, Jos

    2013-01-01

    ""Learning Three.js is a hands-on guide which provides everything you need to start working with the powerful JavaScript library, and start creating awesome in-browser visualizations"".Learning Three.js is written for anyone looking to get started with Three.js, or looking to improve their skills with the popular js library. The book assumes some knowledge of javascript, but you don't need any knowledge of Three.js itself to follow the book.

  10. Learning web development with Bootstrap and AngularJS

    CERN Document Server

    Radford, Stephen

    2015-01-01

    Whether you know a little about Bootstrap or AngularJS, or you're a complete beginner, this book will enhance your capabilities in both frameworks and you'll build a fully functional web app. A working knowledge of HTML, CSS, and JavaScript is required to fully get to grips with Bootstrap and AngularJS.

  11. Building scalable apps with Redis and Node.js

    CERN Document Server

    Johanan, Joshua

    2014-01-01

    If the phrase scalability sounds alien to you, then this is an ideal book for you. You will not need much Node.js experience as each framework is demonstrated in a way that requires no previous knowledge of the framework. You will be building scalable Node.js applications in no time! Knowledge of JavaScript is required.

  12. Node.js by example

    CERN Document Server

    Tsonev, Krasimir

    2015-01-01

    If you are a JavaScript developer with no experience with Node.js or server-side web development, this book is for you. It will lead you through creating a fairly complex social network. You will learn how to work with a database and create real-time communication channels.

  13. EFFECT OF A PLURONIC® P123 FORMULATION ON THE NITRIC OXIDE-GENERATING DRUG JS-K

    Science.gov (United States)

    Kaur, Imit; Kosak, Ken M.; Terrazas, Moises; Herron, James N.; Kern, Steven E.; Boucher, Kenneth M.; Shami, Paul J.

    2014-01-01

    Purpose O2-(2,4-dinitrophenyl)1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] or JS-K is a nitric oxide-producing prodrug of the arylated diazeniumdiolate class with promising anti-tumor activity. JS-K has challenging solubility and stability properties. We aimed to characterize and compare Pluronic® P123-formulated JS-K (P123/JS-K) with free JS-K. Methods We determined micelle size, shape, and critical micelle concentration of Pluronic® P123. Efficacy was evaluated in vitro using HL-60 and U937 cells and in vivo in a xenog raft in NOD/SCID IL2Rγnull mice using HL-60 cells. We compared JS-K and P123/JS-K stability in different media. We also compared plasma protein binding of JS-K and P123/JS-K. We determined the binding and Stern Volmer constants, and thermodynamic parameters. Results Spherical P123/JS-K micelles were smaller than blank P123. P123/JS-K formulation was more stable in buffered saline, whole blood, plasma and RPMI media as compared to free JS-K. P123 affected the protein binding properties of JS-K. In vitro it was as efficacious as JS-K alone when tested in HL-60 and U937 cells and in vivo greater tumor regression was observed for P123/JS-K treated NOD/SCID IL2Rγnull mice when compared to free JS-K-treated NOD/SCID IL2Rγnull mice. Conclusions Pluronic® P123 solubilizes, stabilizes and affects the protein binding characteristics of JS-K. P123/JS-K showed more in vivo anti-tumor activity than free JS-K. PMID:25330743

  14. 20 CFR 658.401 - Types of complaints handled by the JS complaint system.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Types of complaints handled by the JS... § 658.401 Types of complaints handled by the JS complaint system. (a)(1) The types of complaints (JS related complaints) which shall be handled to resolution by the JS complaint system are as follows: (i...

  15. AngularJS in the Wild: A Survey with 460 Developers

    OpenAIRE

    Ramos, Miguel; Valente, Marco Tulio; Terra, Ricardo; Santos, Gustavo

    2016-01-01

    To implement modern web applications, a new family of JavaScript frameworks has emerged, using the MVC pattern. Among these frameworks, the most popular one is AngularJS, which is supported by Google. In spite of its popularity, there is not a clear knowledge on how AngularJS design and features affect the development experience of Web applications. Therefore, this paper reports the results of a survey about AngularJS, including answers from 460 developers. Our contributions include the ident...

  16. Effect of a Pluronic(®) P123 formulation on the nitric oxide-generating drug JS-K.

    Science.gov (United States)

    Kaur, Imit; Kosak, Ken M; Terrazas, Moises; Herron, James N; Kern, Steven E; Boucher, Kenneth M; Shami, Paul J

    2015-04-01

    O(2)-(2,4-dinitrophenyl)1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] or JS-K is a nitric oxide-producing prodrug of the arylated diazeniumdiolate class with promising anti-tumor activity. JS-K has challenging solubility and stability properties. We aimed to characterize and compare Pluronic(®) P123-formulated JS-K (P123/JS-K) with free JS-K. We determined micelle size, shape, and critical micelle concentration of Pluronic(®) P123. Efficacy was evaluated in vitro using HL-60 and U937 cells and in vivo in a xenograft in NOD/SCID IL2Rγ (null) mice using HL-60 cells. We compared JS-K and P123/JS-K stability in different media. We also compared plasma protein binding of JS-K and P123/JS-K. We determined the binding and Stern Volmer constants, and thermodynamic parameters. Spherical P123/JS-K micelles were smaller than blank P123. P123/JS-K formulation was more stable in buffered saline, whole blood, plasma and RPMI media as compared to free JS-K. P123 affected the protein binding properties of JS-K. In vitro it was as efficacious as JS-K alone when tested in HL-60 and U937 cells and in vivo greater tumor regression was observed for P123/JS-K treated NOD/SCID IL2Rγ (null) mice when compared to free JS-K-treated NOD/SCID IL2Rγ (null) mice. Pluronic(®) P123 solubilizes, stabilizes and affects the protein binding characteristics of JS-K. P123/JS-K showed more in vivo anti-tumor activity than free JS-K.

  17. Quality assurance systems at SKODA JS

    International Nuclear Information System (INIS)

    Janecek, P.

    2000-01-01

    In addition to technical requirements put upon the design, manufacture, installation and commissioning of equipment for nuclear power plants, emphasis is laid upon quality assurance of such activities so as to secure nuclear safety of installations over the world. As the technical level of nuclear safety assurance is being enhanced continuously, the requirements are becoming more and more stringent, which is mirrored by the relevant standards and legislation. SKODA JS has always been pursuing the quality goal and has been contributing to this aspect markedly. The quality assurance system at SKODA JS helps the company to satisfy all the appropriate requirements of its customers as well as the applicable standards and regulations. (author)

  18. Leucocytes DNA damage in mice exposed to JS-118 by the comet assay.

    Science.gov (United States)

    Zhang, Tao; Hu, Jiye; Zhang, Yuchao; Zhao, Qianfei; Ning, Jun

    2011-09-01

    JS-118 is an extensively used insecticide in China. The present study investigated the genotoxic effect of JS-118 on whole blood at 24, 48, 72 and 96 h by using alkaline comet assay. Male Kunming mice were given 6.25, 12.5, 25, 50 and 100 mg/kg BW of JS-118 intraperitoneally. A statistically significant increase in all comet parameters indicating DNA damage was observed at 24 h post-treatment (p JS-118 and the period of treatment. The present study provided further information of the potential risk of the genetic damage caused by JS-118.

  19. 20 CFR 658.420 - Establishment of JS complaint system at the ETA regional office.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Establishment of JS complaint system at the... Complaint System Federal Js Complaint System § 658.420 Establishment of JS complaint system at the ETA regional office. (a) Each Regional Administrator shall establish and maintain a JS complaint system at the...

  20. Analisis Statistika dengan SPSS

    OpenAIRE

    Mustari, Kahar

    2012-01-01

    Buku ini membahas tentang berbagai model analisis statistika yang dapat digunakan dalam berbagai bidang penelitian. Pembahasan buku ini dilengkapi pula dengan penerapan analisis statistika yang menggunakan program SPSS versi 20 sehingga memudahkan pembaca untuk menerapkannya. Oleh karena itu, buku ini penting dibaca oleh mahasiswa atau peneliti yang melakukan pengolahan data penelitian.

  1. High performance geospatial and climate data visualization using GeoJS

    Science.gov (United States)

    Chaudhary, A.; Beezley, J. D.

    2015-12-01

    GeoJS (https://github.com/OpenGeoscience/geojs) is an open-source library developed to support interactive scientific and geospatial visualization of climate and earth science datasets in a web environment. GeoJS has a convenient application programming interface (API) that enables users to harness the fast performance of WebGL and Canvas 2D APIs with sophisticated Scalable Vector Graphics (SVG) features in a consistent and convenient manner. We started the project in response to the need for an open-source JavaScript library that can combine traditional geographic information systems (GIS) and scientific visualization on the web. Many libraries, some of which are open source, support mapping or other GIS capabilities, but lack the features required to visualize scientific and other geospatial datasets. For instance, such libraries are not be capable of rendering climate plots from NetCDF files, and some libraries are limited in regards to geoinformatics (infovis in a geospatial environment). While libraries such as d3.js are extremely powerful for these kinds of plots, in order to integrate them into other GIS libraries, the construction of geoinformatics visualizations must be completed manually and separately, or the code must somehow be mixed in an unintuitive way.We developed GeoJS with the following motivations:• To create an open-source geovisualization and GIS library that combines scientific visualization with GIS and informatics• To develop an extensible library that can combine data from multiple sources and render them using multiple backends• To build a library that works well with existing scientific visualizations tools such as VTKWe have successfully deployed GeoJS-based applications for multiple domains across various projects. The ClimatePipes project funded by the Department of Energy, for example, used GeoJS to visualize NetCDF datasets from climate data archives. Other projects built visualizations using GeoJS for interactively exploring

  2. 20 CFR 658.422 - Handling of non-JS-related complaints by the Regional Administrator.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Handling of non-JS-related complaints by the... Federal Js Complaint System § 658.422 Handling of non-JS-related complaints by the Regional Administrator. (a) Each non-JS-related complaint filed by an MSFW alleging violations of employment related laws...

  3. Observation of channeling for 6500 GeV/c protons in the crystal assisted collimation setup for LHC

    International Nuclear Information System (INIS)

    Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Garattini, M.; Gilardoni, S.; Lechner, A.; Losito, R.; Masi, A.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Rossi, R.; Schoofs, P.; Smirnov, G.; Valentino, G.; Breton, D.; Burmistrov, L.; Chaumat, V.; Dubos, S.

    2016-01-01

    Two high-accuracy goniometers equipped with two bent silicon crystals were installed in the betatron cleaning insertion of the CERN Large Hadron Collider (LHC) during its long shutdown. First beam tests were recently performed at the LHC with 450 GeV/c and 6500 GeV/c stored proton beams to investigate the feasibility of beam halo collimation assisted by bent crystals. For the first time channeling of 6500 GeV/c protons was observed in a particle accelerator. A strong reduction of beam losses due to nuclear inelastic interactions in the aligned crystal in comparison with its amorphous orientation was detected. The loss reduction value was about 24. Thus, the results show that deflection of particles by a bent crystal due to channeling is effective for this record particle energy.

  4. Observation of channeling for 6500 GeV/c protons in the crystal assisted collimation setup for LHC

    Energy Technology Data Exchange (ETDEWEB)

    Scandale, W. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Laboratoire de l' Accelerateur Lineaire (LAL), Universite Paris Sud Orsay, Orsay (France); INFN Sezione di Roma, Piazzale Aldo Moro 2, 00185 Rome (Italy); Arduini, G.; Butcher, M.; Cerutti, F.; Garattini, M.; Gilardoni, S.; Lechner, A.; Losito, R.; Masi, A.; Mirarchi, D.; Montesano, S.; Redaelli, S. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Rossi, R. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); INFN Sezione di Roma, Piazzale Aldo Moro 2, 00185 Rome (Italy); Schoofs, P. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Smirnov, G. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); INFN Sezione di Roma, Piazzale Aldo Moro 2, 00185 Rome (Italy); Valentino, G. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Breton, D.; Burmistrov, L.; Chaumat, V.; Dubos, S. [Laboratoire de l' Accelerateur Lineaire (LAL), Universite Paris Sud Orsay, Orsay (France); and others

    2016-07-10

    Two high-accuracy goniometers equipped with two bent silicon crystals were installed in the betatron cleaning insertion of the CERN Large Hadron Collider (LHC) during its long shutdown. First beam tests were recently performed at the LHC with 450 GeV/c and 6500 GeV/c stored proton beams to investigate the feasibility of beam halo collimation assisted by bent crystals. For the first time channeling of 6500 GeV/c protons was observed in a particle accelerator. A strong reduction of beam losses due to nuclear inelastic interactions in the aligned crystal in comparison with its amorphous orientation was detected. The loss reduction value was about 24. Thus, the results show that deflection of particles by a bent crystal due to channeling is effective for this record particle energy.

  5. Anatomy of BioJS, an open source community for the life sciences.

    Science.gov (United States)

    Yachdav, Guy; Goldberg, Tatyana; Wilzbach, Sebastian; Dao, David; Shih, Iris; Choudhary, Saket; Crouch, Steve; Franz, Max; García, Alexander; García, Leyla J; Grüning, Björn A; Inupakutika, Devasena; Sillitoe, Ian; Thanki, Anil S; Vieira, Bruno; Villaveces, José M; Schneider, Maria V; Lewis, Suzanna; Pettifer, Steve; Rost, Burkhard; Corpas, Manuel

    2015-07-08

    BioJS is an open source software project that develops visualization tools for different types of biological data. Here we report on the factors that influenced the growth of the BioJS user and developer community, and outline our strategy for building on this growth. The lessons we have learned on BioJS may also be relevant to other open source software projects.

  6. JS-K promotes apoptosis by inducing ROS production in human prostate cancer cells.

    Science.gov (United States)

    Qiu, Mingning; Chen, Lieqian; Tan, Guobin; Ke, Longzhi; Zhang, Sai; Chen, Hege; Liu, Jianjun

    2017-03-01

    Reactive oxygen species (ROS) are chemical species that alter redox status, and are responsible for inducing carcinogenesis. The purpose of the present study was to assess the effects of the glutathione S transferase-activated nitric oxide donor prodrug, JS-K, on ROS accumulation and on proliferation and apoptosis in human prostate cancer cells. Cell proliferation and apoptosis, ROS accumulation and the activation of the mitochondrial signaling pathway were measured. The results demonstrated that JS-K may inhibit prostate cancer cell growth in a dose- and time-dependent manner, and induce ROS accumulation and apoptosis in a dose-dependent manner. With increasing concentrations of JS-K, expression of pro-apoptotic proteins increased, but Bcl-2 expression decreased. Additionally, the antioxidant N-acetylcysteine reversed JS-K-induced cell apoptosis; conversely, the pro-oxidant glutathione disulfide exacerbated JS-K-induced apoptosis. In conclusion, the data suggest that JS-K induces prostate cancer cell apoptosis by increasing ROS levels.

  7. PENERAPAN ANALISIS SWOC DALAM RENCANA STRATEGIS PENDIDIKAN

    Directory of Open Access Journals (Sweden)

    Hardianto -

    2018-01-01

    Full Text Available Analisis SWOC merupakan salah satu langkah yang bisa diambil dalam membuat sebuah rencana strategis pendidikan. Analisis ini dilakukan untuk melihat secara mendalam situasi internal dan eksternal organisasi. Situasi internal yang dilihat adalah kekuatan (Strenghts dan kelemahan (Weaknesses organisasi pendidikan. Situasi eksternal berupa peluang (Opportinities dan tantangan (Challenges. Untuk membuat sebuah rencana strategis yang baik dapat dilakukan dengan menganalisis setiap kekuatan, kelemahan, peluang dan tantangan. Teknik kartu salju (snow card bisa digunakan dalam melakukan analisis SWOC. Hasil analisis tersebut nantinya akan melahirkan kombinasi strategi kekuatan-peluang, kekuatan-tantangan, kelemahan-peluang dan kelemahan-tantangan.

  8. High-energy irradiation in the management of chondrosarcoma

    International Nuclear Information System (INIS)

    Kim, R.Y.; Salter, M.M.; Brascho, D.J.

    1983-01-01

    We present a retrospective analysis of seven patients with chondrosarcoma of the bone treated by high-energy irradiation between 1961 and 1976. Its major role in this series was prevention of local recurrence in cases with inadequate resection. In three of the five cases in which radiation therapy was adjuvant rather than primary treatment, long-term local control was obtained in a dose of 5,000 to 6,500 rads in five to six weeks. Although primary treatment of chondrosarcoma is surgical, high-dose radiation therapy is indicated when surgical resection is not possible. Chondrosarcoma can respond to high doses of irradiation even though the response is slow

  9. Cytoscape tools for the web age: D3.js and Cytoscape.js exporters [v2; ref status: indexed, http://f1000r.es/4k7

    Directory of Open Access Journals (Sweden)

    Keiichiro Ono

    2014-10-01

    Full Text Available In this paper we present new data export modules for Cytoscape 3 that can generate network files for Cytoscape.js and D3.js. Cytoscape.js exporter is implemented as a core feature of Cytoscape 3, and D3.js exporter is available as a Cytoscape 3 app. These modules enable users to seamlessly export network and table data sets generated in Cytoscape to popular JavaScript library readable formats. In addition, we implemented template web applications for browser-based interactive network visualization that can be used as basis for complex data visualization applications for bioinformatics research. Example web applications created with these tools demonstrate how Cytoscape works in modern data visualization workflows built with traditional desktop tools and emerging web-based technologies. This interactivity enables researchers more flexibility than with static images, thereby greatly improving the quality of insights researchers can gain from them.

  10. AngularJS directives

    CERN Document Server

    Vanston, Alex

    2013-01-01

    This book uses a practical, step-by-step approach, starting with how to build directives from the ground up before moving on to creating web applications comprised of multiple modules all working together to provide the best user experience possible.This book is intended for intermediate JavaScript developers who are looking to enhance their understanding of single-page web application development with a focus on AngularJS and the JavaScript MVC frameworks.It is expected that readers will understand basic JavaScript patterns and idioms and can recognize JSON formatted data.

  11. CELLULAR DISTRIBUTION STUDIES OF THE NITRIC OXIDE-GENERATING ANTINEOPLASTIC PRODRUG JS-K, FORMULATED IN PLURONIC P123 MICELLES

    Science.gov (United States)

    Kaur, Imit; Terrazas, Moises; Kosak, Ken M.; Kern, Steven E.; Boucher, Kenneth M.; Shami, Paul J.

    2014-01-01

    Objective Nitric oxide (NO) possesses anti-tumor activity. It induces differentiation and apoptosis in acute myeloid leukemia (AML) cells. The NO prodrug O2-(2,4-dinitrophenyl)1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate, or JS-K, has potent antileukemic activity. JS-K is also active in vitro and in vivo against multiple myeloma, prostate cancer, non-small cell lung cancer, glioma and liver cancer. Using the Pluronic® P123 polymer, we have developed a micelle formulation for JS-K in order to increase its solubility and stability. The goal of the current study was to investigate the cellular distribution of JS-K in AML cells. Methods We investigated the intracellular distribution of JS-K (free drug) and JS-K formulated in P123 micelles (P123/JS-K) using HL-60 AML cells. We also studied the S-glutathionylating effects of JS-K on proteins in the cytoplasmic and nuclear cellular fractions. Key findings Both free JS-K and P123/JS-K accumulate primarily in the nucleus. Both free JS-K and P123/JS-K induced S-glutathionylation of nuclear proteins, although the effect produced was more pronounced with P123/JS-K. Minimal S-glutathionylation of cytoplasmic proteins was observed. Conclusions We conclude that a micelle formulation of JS-K increases its accumulation in the nucleus. Post-translational protein modification through S-glutathionylation may contribute to JS-K’s anti-leukemic properties. PMID:23927471

  12. Research on TCP/IP network communication based on Node.js

    Science.gov (United States)

    Huang, Jing; Cai, Lixiong

    2018-04-01

    In the face of big data, long connection and high synchronization, TCP/IP network communication will cause performance bottlenecks due to its blocking multi-threading service model. This paper presents a method of TCP/IP network communication protocol based on Node.js. On the basis of analyzing the characteristics of Node.js architecture and asynchronous non-blocking I/O model, the principle of its efficiency is discussed, and then compare and analyze the network communication model of TCP/IP protocol to expound the reasons why TCP/IP protocol stack is widely used in network communication. Finally, according to the large data and high concurrency in the large-scale grape growing environment monitoring process, a TCP server design based on Node.js is completed. The results show that the example runs stably and efficiently.

  13. SATCHMO-JS: a webserver for simultaneous protein multiple sequence alignment and phylogenetic tree construction.

    Science.gov (United States)

    Hagopian, Raffi; Davidson, John R; Datta, Ruchira S; Samad, Bushra; Jarvis, Glen R; Sjölander, Kimmen

    2010-07-01

    We present the jump-start simultaneous alignment and tree construction using hidden Markov models (SATCHMO-JS) web server for simultaneous estimation of protein multiple sequence alignments (MSAs) and phylogenetic trees. The server takes as input a set of sequences in FASTA format, and outputs a phylogenetic tree and MSA; these can be viewed online or downloaded from the website. SATCHMO-JS is an extension of the SATCHMO algorithm, and employs a divide-and-conquer strategy to jump-start SATCHMO at a higher point in the phylogenetic tree, reducing the computational complexity of the progressive all-versus-all HMM-HMM scoring and alignment. Results on a benchmark dataset of 983 structurally aligned pairs from the PREFAB benchmark dataset show that SATCHMO-JS provides a statistically significant improvement in alignment accuracy over MUSCLE, Multiple Alignment using Fast Fourier Transform (MAFFT), ClustalW and the original SATCHMO algorithm. The SATCHMO-JS webserver is available at http://phylogenomics.berkeley.edu/satchmo-js. The datasets used in these experiments are available for download at http://phylogenomics.berkeley.edu/satchmo-js/supplementary/.

  14. BioJS: an open source JavaScript framework for biological data visualization.

    Science.gov (United States)

    Gómez, John; García, Leyla J; Salazar, Gustavo A; Villaveces, Jose; Gore, Swanand; García, Alexander; Martín, Maria J; Launay, Guillaume; Alcántara, Rafael; Del-Toro, Noemi; Dumousseau, Marine; Orchard, Sandra; Velankar, Sameer; Hermjakob, Henning; Zong, Chenggong; Ping, Peipei; Corpas, Manuel; Jiménez, Rafael C

    2013-04-15

    BioJS is an open-source project whose main objective is the visualization of biological data in JavaScript. BioJS provides an easy-to-use consistent framework for bioinformatics application programmers. It follows a community-driven standard specification that includes a collection of components purposely designed to require a very simple configuration and installation. In addition to the programming framework, BioJS provides a centralized repository of components available for reutilization by the bioinformatics community. http://code.google.com/p/biojs/. Supplementary data are available at Bioinformatics online.

  15. Instant IntroJs

    CERN Document Server

    Arasteh, Ehsan

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. A simple starter that will guide you through IntroJs from scratch to advanced topics using a simple step by step approach with useful examples along the way.This book is for web designers who want to create an interactive step-by-step introduction for showing specific or all parts of an application or website to users. Basic JavaScript programming and knowledge of HTML and CSS is required. No knowledge of any other JavaScript libraries is needed

  16. Web-Based Geospatial Visualization of GPM Data with CesiumJS

    Science.gov (United States)

    Lammers, Matt

    2018-01-01

    Advancements in the capabilities of JavaScript frameworks and web browsing technology have made online visualization of large geospatial datasets such as those coming from precipitation satellites viable. These data benefit from being visualized on and above a three-dimensional surface. The open-source JavaScript framework CesiumJS (http://cesiumjs.org), developed by Analytical Graphics, Inc., leverages the WebGL protocol to do just that. This presentation will describe how CesiumJS has been used in three-dimensional visualization products developed as part of the NASA Precipitation Processing System (PPS) STORM data-order website. Existing methods of interacting with Global Precipitation Measurement (GPM) Mission data primarily focus on two-dimensional static images, whether displaying vertical slices or horizontal surface/height-level maps. These methods limit interactivity with the robust three-dimensional data coming from the GPM core satellite. Integrating the data with CesiumJS in a web-based user interface has allowed us to create the following products. We have linked with the data-order interface an on-the-fly visualization tool for any GPM/partner satellite orbit. A version of this tool also focuses on high-impact weather events. It enables viewing of combined radar and microwave-derived precipitation data on mobile devices and in a way that can be embedded into other websites. We also have used CesiumJS to visualize a method of integrating gridded precipitation data with modeled wind speeds that animates over time. Emphasis in the presentation will be placed on how a variety of technical methods were used to create these tools, and how the flexibility of the CesiumJS framework facilitates creative approaches to interact with the data.

  17. Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements

    KAUST Repository

    Baranasic, Damir

    2014-07-17

    The genome sequence of Streptomyces rimosus R6-500, an industrially improved strain which produces high titers of the important antibiotic oxytetracycline, is reported, as well as the genome sequences of two derivatives arising due to the genetic instability of the strain.

  18. Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements

    KAUST Repository

    Baranasic, Damir; Zucko, Jurica; Nair, Mridul; Pain, Arnab; Long, Paul F.; Hranueli, Daslav; Cullum, John; Starcevic, Antonio

    2014-01-01

    The genome sequence of Streptomyces rimosus R6-500, an industrially improved strain which produces high titers of the important antibiotic oxytetracycline, is reported, as well as the genome sequences of two derivatives arising due to the genetic instability of the strain.

  19. Gamma irradiation service in Mexico; Servicio de Irradiacion Gamma en Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Liceaga C, G; Martinez A, L; Mendez T, D; Ortiz A, G; Olvera G, R [Departamento del Irradiador Gamma. Instituto Nacional de Investigaciones Nucleares, Apdo. Postal 18-1027, Col. Escandon, 11801 Mexico D.F. (Mexico)

    1998-12-31

    In 1980 it was installed in Mexico, on the National Institute of Nuclear Research, an irradiator model J S-6500 of a canadian manufacture. Actually, this is the greatest plant in the Mexican Republic that offers a gamma irradiation process at commercial level to diverse industries. However, seeing that the demand for sterilize those products were not so much as the irradiation capacity it was opted by the incursion in other types of products. During 17 years had been irradiated a great variety of products grouped of the following form: dehydrated foods, disposable products for medical use, cosmetics, medicaments, various. Nowadays the capacity of the irradiator is saturated virtue of it is operated the 24 hours during the 365 days of the year and only its operation is suspended by the preventive and corrective maintenance. However, the fresh food market does not be attended since this irradiator was designed for doses greater than 10 kGy (1.0 Mrad)

  20. JS3P: junior staff programme pilot project

    International Nuclear Information System (INIS)

    Pretrel, H.; Tregoures, N.; Bessiron, V.; Dehoyos, A.; Delvallee, I.; Brisson, N.; Debayle, C.; Dubreuil, M.; Nicaise, G.; Perignon, J.P.; Richard, J.; Reinke, N.; Kaulard, J.; Burgener, M.; Keesmann, S.; Schramm, B.; Seubert, A.; Sternkopf, J.; Thuma, G.; Weber, S.; Smidts, O.; Maillet, E.; Bucalossi, A.; Van haesendonck, M.; Uyttenhove, W.; Mertens, J.

    2006-01-01

    Concept: The objective of the project is to allow junior staff members from the European Technical Safety Organisations (TSOs), IRSN, GRS and AVN, to work together with the final goal of creating a junior staff network, based on technical, cultural and personal interests. These projects are to show junior staff members at a very early stage during their career the need for European collaborations. They are also a tool to explore new subjects of co-operation. It is an initiative that should strengthen the links between the organisations and contribute to establishing the future of nuclear safety in Europe. A JS3P (Junior Staff Programme Pilot Project) is a project done jointly by 'junior' staff members from the three TSOs, where experience of 'seniors' is also integrated when needed. Compared to other collaborative activities, it has certain specific features. The JS3P favours staff exchanges, and technical meetings of several days should be planned during a project in order to encourage people to work together. Technical objectives are shared and the work is done jointly (reports, articles). The team involved in the JS3P should be as small as possible to favour its efficiency. The JS3P is short and easy to realize. Its duration is fixed to a maximum of about 12 months with the option to be prolonged. Typical topics are bibliographic work, comparison issues, scientific surveys, benchmark exercises and prospective investigations on innovative ideas. They can be linked to existing joint projects and then form a smaller module integrated into the large project. Topics may concern prospective issues, tentatively investigating new topics that can be seen as exploratory co-operation projects. Subjects may also concern research issues that are not a priority but that deserve to be investigated as new attractive topics. The JS3P is defined and managed by junior staff members. It is approved by a management board committee and supervised by a technical steering committee

  1. Juicebox.js Provides a Cloud-Based Visualization System for Hi-C Data.

    Science.gov (United States)

    Robinson, James T; Turner, Douglass; Durand, Neva C; Thorvaldsdóttir, Helga; Mesirov, Jill P; Aiden, Erez Lieberman

    2018-02-28

    Contact mapping experiments such as Hi-C explore how genomes fold in 3D. Here, we introduce Juicebox.js, a cloud-based web application for exploring the resulting datasets. Like the original Juicebox application, Juicebox.js allows users to zoom in and out of such datasets using an interface similar to Google Earth. Juicebox.js also has many features designed to facilitate data reproducibility and sharing. Furthermore, Juicebox.js encodes the exact state of the browser in a shareable URL. Creating a public browser for a new Hi-C dataset does not require coding and can be accomplished in under a minute. The web app also makes it possible to create interactive figures online that can complement or replace ordinary journal figures. When combined with Juicer, this makes the entire process of data analysis transparent, insofar as every step from raw reads to published figure is publicly available as open source code. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  2. JS-MS: a cross-platform, modular javascript viewer for mass spectrometry signals.

    Science.gov (United States)

    Rosen, Jebediah; Handy, Kyle; Gillan, André; Smith, Rob

    2017-11-06

    Despite the ubiquity of mass spectrometry (MS), data processing tools can be surprisingly limited. To date, there is no stand-alone, cross-platform 3-D visualizer for MS data. Available visualization toolkits require large libraries with multiple dependencies and are not well suited for custom MS data processing modules, such as MS storage systems or data processing algorithms. We present JS-MS, a 3-D, modular JavaScript client application for viewing MS data. JS-MS provides several advantages over existing MS viewers, such as a dependency-free, browser-based, one click, cross-platform install and better navigation interfaces. The client includes a modular Java backend with a novel streaming.mzML parser to demonstrate the API-based serving of MS data to the viewer. JS-MS enables custom MS data processing and evaluation by providing fast, 3-D visualization using improved navigation without dependencies. JS-MS is publicly available with a GPLv2 license at github.com/optimusmoose/jsms.

  3. JS-K, a nitric oxide-releasing prodrug, induces breast cancer cell death while sparing normal mammary epithelial cells.

    Science.gov (United States)

    McMurtry, Vanity; Saavedra, Joseph E; Nieves-Alicea, René; Simeone, Ann-Marie; Keefer, Larry K; Tari, Ana M

    2011-04-01

    Targeted therapy with reduced side effects is a major goal in cancer research. We investigated the effects of JS-K, a nitric oxide (NO) prodrug designed to release high levels of NO when suitably activated, on human breast cancer cell lines, on non-transformed human MCF-10A mammary cells, and on normal human mammary epithelial cells (HMECs). Cell viability assay, flow cytometry, electron microscopy, and Western blot analysis were used to study the effects of JS-K on breast cancer and on mammary epithelial cells. After a 3-day incubation, the IC50s of JS-K against the breast cancer cells ranged from 0.8 to 3 µM. However, JS-K decreased the viability of the MCF-10A cells by only 20% at 10-µM concentration, and HMECs were unaffected by 10 µM JS-K. Flow cytometry indicated that JS-K increased the percentages of breast cancer cells under-going apoptosis. Interestingly, flow cytometry indicated that JS-K increased acidic vesicle organelle formation in breast cancer cells, suggesting that JS-K induced autophagy in breast cancer cells. Electron microscopy confirmed that JS-K-treated breast cancer cells underwent autophagic cell death. Western blot analysis showed that JS-K induced the expression of microtubule light chain 3-II, another autophagy marker, in breast cancer cells. However, JS-K did not induce apoptosis or autophagy in normal human mammary epithelial cells. These data indicate that JS-K selectively induces programmed cell death in breast cancer cells while sparing normal mammary epithelial cells under the same conditions. The selective anti-tumor activity of JS-K warrants its further investigation in breast tumors.

  4. Vcs.js - Visualization Control System for the Web

    Science.gov (United States)

    Chaudhary, A.; Lipsa, D.; Doutriaux, C.; Beezley, J. D.; Williams, D. N.; Fries, S.; Harris, M. B.

    2016-12-01

    VCS is a general purpose visualization library, optimized for climate data, which is part of the UV-CDAT system. It provides a Python API for drawing 2D plots such as lineplots, scatter plots, Taylor diagrams, data colored by scalar values, vector glyphs, isocontours and map projections. VCS is based on the VTK library. Vcs.js is the corresponding JavaScript API, designed to be as close as possible to the original VCS Python API and to provide similar functionality for the Web. Vcs.js includes additional functionality when compared with VCS. This additional API is used to introspect data files available on the server and variables available in a data file. Vcs.js can display plots in the browser window. It always works with a server that reads a data file, extracts variables from the file and subsets the data. From this point, two alternate paths are possible. First the system can render the data on the server using VCS producing an image which is send to the browser to be displayed. This path works for for all plot types and produces a reference image identical with the images produced by VCS. This path uses the VTK-Web library. As an optimization, usable in certain conditions, a second path is possible. Data is packed, and sent to the browser which uses a JavaScript plotting library, such as plotly, to display the data. Plots that work well in the browser are line-plots, scatter-plots for any data and many other plot types for small data and supported grid types. As web technology matures, more plots could be supported for rendering in the browser. Rendering can be done either on the client or on the server and we expect that the best place to render will change depending on the available web technology, data transfer costs, server management costs and value provided to users. We intend to provide a flexible solution that allows for both client and server side rendering and a meaningful way to choose between the two. We provide a web-based user interface called v

  5. JS-K, an arylating nitric oxide (NO) donor, has synergistic anti-leukemic activity with cytarabine (ARA-C).

    Science.gov (United States)

    Shami, Paul J; Maciag, Anna E; Eddington, Jordan K; Udupi, Vidya; Kosak, Ken M; Saavedra, Joseph E; Keefer, Larry K

    2009-11-01

    We have designed prodrugs that release nitric oxide (NO) on metabolism by glutathione S-transferases (GST). This design exploits the upregulation of GST in acute myeloid leukemia (AML) cells. O(2)-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K, a member of this class) has potent anti-leukemic activity. HL-60 myeloid leukemia cells were used for in vitro studies of the combination of JS-K with daunorubicin (DAUNO), cytarabine (ARA-C) or etoposide (ETOP) using the median effect method to determine synergistic, antagonistic, or additive effects. Combinations of JS-K added simultaneously, 2h before or 2h after the other compounds were used. JS-K and DAUNO were antagonistic in all three drug sequences. JS-K and ETOP were also antagonistic but to a lesser degree. JS-K and ARA-C showed strong synergy. The combination index at the 50% fraction affected was 0.37+/-0.23, 0.24+/-0.27, and 0.15+/-0.11 for simultaneous, JS-K first and ARA-C first additions, respectively. JS-K by itself induced DNA strand breaks at relatively high concentrations. However, at submicromolar concentrations, it significantly augmented ARA-C-induced DNA strand breaks. NMR spectroscopy revealed no evidence of chemical interaction between JS-K and the other chemotherapeutic agents. We conclude that ARA-C and JS-K have synergistic anti-leukemic activity and warrant further exploration in combination.

  6. Contrasting growth properties of Nocardioides JS614 on threedifferent vinyl halides.

    Science.gov (United States)

    Taylor, Anne E; Bottomley, Peter J; Semprini, Lewis

    2018-02-01

    Ethene (ETH)-grown inocula of Nocardioides JS614 grow on vinyl chloride (VC), vinyl fluoride (VF), or vinyl bromide (VB) as the sole carbon and energy source, with faster growth rates and higher cell yields on VC and VF than on VB. However, whereas acetate-grown inocula of JS614 grow on VC and VF after a lag period, growth on VB did not occur unless supplemental ethene oxide (EtO) was present in the medium. Despite inferior growth on VB, the maximum rate of VB consumption by ETH-grown cells was ~ 50% greater than the rates of VC and VF consumption, but Br - release during VB consumption was non-stoichiometric with VB consumption (~ 66%) compared to 100% release of Cl - and F - during VC and VF consumption. Evidence was obtained for VB turnover-dependent toxicity of cell metabolism in JS614 with both acetate-dependent respiration and growth being significantly reduced by VB turnover, but no VC or VF turnover-dependent toxicity of growth was detected. Reduced growth rate and cell yield of JS614 on VB probably resulted from a combination of inefficient metabolic processing of the highly unstable VB epoxide (t 0.5  = 45 s), accompanied by growth inhibitory effects of VB metabolites on acetate-dependent metabolism. The exact role(s) of EtO in promoting growth of alkene repressed JS614 on VB remains unresolved, with evidence of EtO inducing epoxide consuming activity prior to an increase in alkene oxidizing activity and supplementing reductant supply when VB is the growth substrate.

  7. Exposition index calculation from different points in a gamma sterilization plant radiation room

    International Nuclear Information System (INIS)

    Carrasco, A.H.

    1983-01-01

    Radiation fields produced by a JS-6500 rectangular irradiator source were evaluated. Knowledge of the values of these fields is necessary in irradiation and health physics processes. Techniques for evaluating the dose rates from puntual, linear and plane sources were applied and computer programs for the three sources designed. Fricke, cupric-ferrous and red acrilic dosimetric systems were used, to verify the eight points located along the interior walls of the irradiation room, around the source with 936, 987 Ci of Co-60 (1st-March 1980). When considering the distance between the source and each point of interest the calculated exposition indexes obtained were practically the same for the three source types and were up to 35% greater than the experimental values; in contrast when absorption and buildup of the source were taken in to account, the experimental values were higher than the calculated ones by up to 16%, this in estimating the produced exposition index for a rectangular source at least there two parameters should be included. (author)

  8. Gene expression profiling for nitric oxide prodrug JS-K to kill HL-60 myeloid leukemia cells.

    Science.gov (United States)

    Liu, Jie; Malavya, Swati; Wang, Xueqian; Saavedra, Joseph E; Keefer, Larry K; Tokar, Erik; Qu, Wei; Waalkes, Michael P; Shami, Paul J

    2009-07-01

    The nitric oxide (NO) prodrug JS-K is shown to have anticancer activity. To profile the molecular events associated with the anticancer effects of JS-K, HL-60 leukemia cells were treated with JS-K and subjected to microarray and real-time RT-PCR analysis. JS-K induced concentration- and time-dependent gene expression changes in HL-60 cells corresponding to the cytolethality effects. The apoptotic genes (caspases, Bax, and TNF-alpha) were induced, and differentiation-related genes (CD14, ITGAM, and VIM) were increased. For acute phase protein genes, some were increased (TP53, JUN) while others were suppressed (c-myc, cyclin E). The expression of anti-angiogenesis genes THBS1 and CD36 and genes involved in tumor cell migration such as tissue inhibitors of metalloproteinases, were also increased by JS-K. Confocal analysis confirmed key gene changes at the protein levels. Thus, multiple molecular events are associated with JS-K effects in killing HL-60, which could be molecular targets for this novel anticancer NO prodrug.

  9. Skoda JS's proposal for Slovak nuclear power industry

    International Nuclear Information System (INIS)

    Borovec, J.

    2004-01-01

    In this presentation author deals with the structure and revenues of the Skoda JS, a.s., as well as productions of the company for nuclear power industry in the Czech Republic, Ukraine and the Slovak Republic

  10. Analisis Harmonisa Inverter PWM Satu Fasa

    OpenAIRE

    Rejeki Simanjorang

    2008-01-01

    Pada tesis ini dianalisis harmonisa inverter PWM satu fasa. Inverter PWM satu fasa yang akan ditinjau adalah inverter satu fasa jembatan penuh (konvensional) dan inverter komposit. Analisis difokuskan pada penentuan pola penyaklaran yang optimum agar pembangkitan harmonisa dan switching losses inverter rendah. Untuk menentukan pola penyaklaran optimum maka dilakukan analisis yang berbasis pada rangkaian ekivalen harmonisa inverter satu fasa. Dengan menggunakan pola penyaklaran optimum, kedua ...

  11. ANALISIS PENYEBAB BANJIR KALI JUANA

    Directory of Open Access Journals (Sweden)

    Teguh Marhendi

    2017-04-01

    Full Text Available Kali Juana yang berada di Kabupaten Pati dan Kudus serta sebagian kecil di Kabupaten Grobogan dan Blora, merupakan kawasan banjir. Kejadian banjir di Kali Juana, sudah menjadi rutinitas setiap musim hujan.Dari Januari sampai bulan Mei 2016tercatat terjadi 11 kejadian banjir dibeberapa wilayah, seperti Kecamatan Kaliwungu, Undaan dan Mejobo (Kab. Kudus serta Pati, Margorejo dan Juwana (Kab. Pati. Kali Juana merupakan bifurkasi Kali Serang pada Pintu Wilalung, yang berfungsi sebagai pintu pengatur banjir (dibangun pada zaman Belanda tahun 1918, melalui Kali Babalan menuju ke Kali Juana. Tulisan inidimaksudkan untuk menganalisis penyebab kejadian banjir di Kali Juana. Analisis dilakukan dengan melakukan kajani dan analisis hujan serta mekanisme aliran. Hasil analisis menunjukkan bahwa kondisi Kali Juana dari pertemuan Kali Logung di pintu Wilalung sampai hilir telah mengalami pendangkalan akibat kemiringan dasar atau topografi yang landai, dan mengakibatkan mudah terjadi sedimentasi sehingga mengurangi kapasitas pengaliran. Hal ini menyebabkan luapan banjir sering menggenangi wilayah Kabupaten Kudus dan Pati.

  12. Analisi matematica

    CERN Document Server

    Canuto, Claudio

    2014-01-01

    Il presente testo intende essere di supporto ad un secondo insegnamento di Analisi Matematica in quei corsi di studio (quali ad esempio Ingegneria, Informatica, Fisica) in cui lo strumento matematico parte significativa della formazione dell'allievo. I concetti e i metodi fondamentali del calcolo differenziale ed integrale in più variabili, le serie di funzioni e le equazioni differenziali ordinarie sono presentati con l'obiettivo primario di addestrare lo studente ad un loro uso operativo, ma critico. L'impostazione didattica dell'opera ricalca quella usata nel testo parallelo di Analisi Matematica I. La modalità di presentazione degli argomenti ne permette un uso flessibile e modulare. Lo stile adottato privilegia la chiarezza e la linearità dell'esposizione. Il testo organizzato su due livelli di lettura. Uno, più essenziale, permette allo studente di cogliere i concetti indispensabili della materia, di familiarizzarsi con le relative tecniche di calcolo e di trovare le giustificazioni dei principali r...

  13. jsPsych: a JavaScript library for creating behavioral experiments in a Web browser.

    Science.gov (United States)

    de Leeuw, Joshua R

    2015-03-01

    Online experiments are growing in popularity, and the increasing sophistication of Web technology has made it possible to run complex behavioral experiments online using only a Web browser. Unlike with offline laboratory experiments, however, few tools exist to aid in the development of browser-based experiments. This makes the process of creating an experiment slow and challenging, particularly for researchers who lack a Web development background. This article introduces jsPsych, a JavaScript library for the development of Web-based experiments. jsPsych formalizes a way of describing experiments that is much simpler than writing the entire experiment from scratch. jsPsych then executes these descriptions automatically, handling the flow from one task to another. The jsPsych library is open-source and designed to be expanded by the research community. The project is available online at www.jspsych.org .

  14. phylo-node: A molecular phylogenetic toolkit using Node.js.

    Science.gov (United States)

    O'Halloran, Damien M

    2017-01-01

    Node.js is an open-source and cross-platform environment that provides a JavaScript codebase for back-end server-side applications. JavaScript has been used to develop very fast and user-friendly front-end tools for bioinformatic and phylogenetic analyses. However, no such toolkits are available using Node.js to conduct comprehensive molecular phylogenetic analysis. To address this problem, I have developed, phylo-node, which was developed using Node.js and provides a stable and scalable toolkit that allows the user to perform diverse molecular and phylogenetic tasks. phylo-node can execute the analysis and process the resulting outputs from a suite of software options that provides tools for read processing and genome alignment, sequence retrieval, multiple sequence alignment, primer design, evolutionary modeling, and phylogeny reconstruction. Furthermore, phylo-node enables the user to deploy server dependent applications, and also provides simple integration and interoperation with other Node modules and languages using Node inheritance patterns, and a customized piping module to support the production of diverse pipelines. phylo-node is open-source and freely available to all users without sign-up or login requirements. All source code and user guidelines are openly available at the GitHub repository: https://github.com/dohalloran/phylo-node.

  15. JS-K, a glutathione S-transferase-activated nitric oxide donor with antineoplastic activity in malignant gliomas.

    Science.gov (United States)

    Weyerbrock, Astrid; Osterberg, Nadja; Psarras, Nikolaos; Baumer, Brunhilde; Kogias, Evangelos; Werres, Anna; Bette, Stefanie; Saavedra, Joseph E; Keefer, Larry K; Papazoglou, Anna

    2012-02-01

    Glutathione S-transferases (GSTs) control multidrug resistance and are upregulated in many cancers, including malignant gliomas. The diazeniumdiolate JS-K generates nitric oxide (NO) on enzymatic activation by glutathione and GST, showing promising NO-based anticancer efficacy. To evaluate the role of NO-based antitumor therapy with JS-K in U87 gliomas in vitro and in vivo. U87 glioma cells and primary glioblastoma cell lines were exposed to JS-K and a variety of inhibitors to study cell death by necrosis, apoptosis, and other mechanisms. GST expression was evaluated by immunocytochemistry, polymerase chain reaction, and Western blot, and NO release from JS-K was studied with a NO assay. The growth-inhibitory effect of JS-K was studied in a U87 xenograft model in vivo. Dose-dependent inhibition of cell proliferation was observed in human U87 glioma cells and primary glioblastoma cells in vitro. Cell death was partially induced by caspase-dependent apoptosis, which could be blocked by Z-VAD-FMK and Q-VD-OPH. Inhibition of GST by sulfasalazine, cGMP inhibition by ODQ, and MEK1/2 inhibition by UO126 attenuated the antiproliferative effect of JS-K, suggesting the involvement of various intracellular death signaling pathways. Response to JS-K correlated with mRNA and protein expression of GST and the amount of NO released by the glioma cells. Growth of U87 xenografts was reduced significantly, with immunohistochemical evidence for increased necrosis and apoptosis and reduced proliferation. Our data show for the first time the potent antiproliferative effect of JS-K in gliomas in vitro and in vivo. These findings warrant further investigation of this novel NO-releasing prodrug in gliomas.

  16. A reactive oxygen species activation mechanism contributes to JS-K-induced apoptosis in human bladder cancer cells.

    Science.gov (United States)

    Qiu, Mingning; Chen, Lieqian; Tan, Guobin; Ke, Longzhi; Zhang, Sai; Chen, Hege; Liu, Jianjun

    2015-10-13

    Reactive oxygen species (ROS) and cellular oxidant stress are regulators of cancer cells. The alteration of redox status, which is induced by increased generation of ROS, results in increased vulnerability to oxidative stress. The aim of this study is to investigate the influence of O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K, C13H16N6O8) on proliferation and apoptosis in bladder cancer cells and explored possible ROS-related mechanisms. Our results indicated that JS-K could suppress bladder cancer cell proliferation in a concentration- and time-dependent manner and induce apoptosis and ROS accumulation in a concentration-dependent manner. With increasing concentrations of JS-K, expression of proteins that are involved in cell apoptosis increased in a concentration-dependent manner. Additionally, the antioxidant N-acetylcysteine (NAC) reversed JS-K-induced cell apoptosis; conversely, the prooxidant oxidized glutathione (GSSG) exacerbated JS-K-induced cell apoptosis. Furthermore, we found that nitrites, which were generated from the oxidation of JS-K-released NO, induced apoptosis in bladder cancer cells to a lower extent through the ROS-related pathway. In addition, JS-K was shown to enhance the chemo-sensitivity of doxorubicin in bladder cancer cells. Taken together, the data suggest that JS-K-released NO induces bladder cancer cell apoptosis by increasing ROS levels, and nitrites resulting from oxidation of NO have a continuous apoptosis-inducing effect.

  17. pileup.js: a JavaScript library for interactive and in-browser visualization of genomic data.

    Science.gov (United States)

    Vanderkam, Dan; Aksoy, B Arman; Hodes, Isaac; Perrone, Jaclyn; Hammerbacher, Jeff

    2016-08-01

    P: ileup.js is a new browser-based genome viewer. It is designed to facilitate the investigation of evidence for genomic variants within larger web applications. It takes advantage of recent developments in the JavaScript ecosystem to provide a modular, reliable and easily embedded library. The code and documentation for pileup.js is publicly available at https://github.com/hammerlab/pileup.js under the Apache 2.0 license. correspondence@hammerlab.org. © The Author 2016. Published by Oxford University Press.

  18. JS-K, a nitric oxide prodrug, induces cytochrome c release and caspase activation in HL-60 myeloid leukemia cells.

    Science.gov (United States)

    Udupi, Vidya; Yu, Margaret; Malaviya, Swati; Saavedra, Joseph E; Shami, Paul J

    2006-10-01

    Nitric oxide (NO) induces differentiation and apoptosis in acute myelogenous leukemia (AML) cells. The NO prodrug O2-(2,4-dinitrophenyl)1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate, or JS-K, has potent antileukemic activity. JS-K induces apoptosis in HL-60 cells by a caspase-dependent mechanism. The purpose of this study was to determine the pathway through which JS-K induces apoptosis. We show that JS-K alters mitochondrial membrane potential (DeltaPsim) and induces cytochrome c release from mitochondria into the cytoplasm. Treatment with JS-K resulted in activation of Caspase (Casp) 9, Casp 3 and Casp 8. JS-K constitutes a promising lead for a new class of anti-leukemic agents.

  19. ANALISIS VARIABILITAS CURAH HUJAN DAN SUHU DI BALI

    Directory of Open Access Journals (Sweden)

    Ogi Setiawan

    2017-01-01

    Full Text Available Indonesia sebagai negara kepulauan yang terdiri dari pulau-pulau besar dan kecil menjadi sangat rentan terhadap dampak perubahan iklim. Salah satu pulau yang juga rentan terhadap perubahan iklim adalah pulau Bali. Dampak potensial adanya perubahan iklim adalah perubahan pola hujan, peningkatan suhuudaradankenaikanpermukaanlaut. Sektoryangakanmenerimadampakperubahaniklimdengan serius adalah sektor kehutanan dan pertanian. Untuk mendukung upaya mitigasi dan adaptasi maka diperlukan informasi perubahan iklim yang terjadi. Penelitian ini bertujuan untuk mengetahui variabilitas iklim di Bali. Metode yang digunakan adalah analisis kecenderungan curah hujan, analisis perubahan suhu udara, analisis perubahan tipe iklim dan analisis pergeseran bulan basah, lembab dan kering. Data hujan yang digunakan adalah data hujan dari GPCC (1961-1998 dan BMKG Bali (19992008, sedangkan data suhu berasal dari BMKG Bali (2004-2008. Hasil analisis menunjukkan bahwa di pulau Bali secara umum sudah mengalami perubahan iklim. Tipe iklim berdasarkan Schmidt-Ferguson mengalami perubahan dari relatif basah menjadi agak kering. Suhu udara rata-rata bulanan serta curah hujan bulanan dan tahunan memiliki kecenderungan yang semakin meningkat. Bulan basah dan bulan kering telah mengalami pergeseran dan perubahan jumlahnya. Dampak perubahan iklim terhadap ekosistem hutan di Bali belum diketahui dengan pasti, namun terdapat beberapa implikasi perubahan iklim terhadap sektor kehutanan diantaranya kebakaran hutan dan perubahan jadwal penanaman.

  20. The nitric oxide prodrug JS-K and its structural analogues as cancer therapeutic agents.

    Science.gov (United States)

    Maciag, Anna E; Saavedra, Joseph E; Chakrapani, Harinath

    2009-09-01

    Nitric oxide (NO) prodrugs of the diazeniumdiolate class are routinely used as reliable sources of nitric oxide in chemical and biological laboratory settings. O(2)-(2,4-dinitrophenyl) diazeniumdiolates, which are derivatized forms of ionic diazeniumdiolates, have been found to show potent anti-proliferative activity in a variety of cancer cells, presumably through the effects of NO. One important member of this class of diazeniumdiolates, O(2)-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K), has shown promise as a novel cancer therapeutic agent in a number of animal models. This review describes the developments in chemical and biochemical characterization and structure-activity relationship of JS-K and its analogues. In addition, some molecular mechanistic insights into the observed anti-proliferative activity of JS-K are discussed. Finally, a structural motif is presented for O(2)-(aryl) diazeniumdiolate nitric oxide prodrugs that show potency comparable with that of JS-K.

  1. JS-K, a nitric oxide pro-drug, regulates growth and apoptosis through the ubiquitin-proteasome pathway in prostate cancer cells.

    Science.gov (United States)

    Tan, Guobin; Qiu, Mingning; Chen, Lieqian; Zhang, Sai; Ke, Longzhi; Liu, Jianjun

    2017-05-26

    In view of the fact that JS-K might regulate ubiquitin E3 ligase and that ubiquitin E3 ligase plays an important role in the mechanism of CRPC formation, the goal was to investigate the probable mechanism by which JS-K regulates prostate cancer cells. Proliferation inhibition by JS-K on prostate cancer cells was examined usingCCK-8 assays. Caspase 3/7 activity assays and flow cytometry were performed to examine whether JS-K induced apoptosis in prostate cancer cells. Western blotting and co-immunoprecipitation analyses investigated JS-K's effects on the associated apoptosis mechanism. Real time-PCR and Western blotting were performed to assess JS-K's effect on transcription of specific AR target genes. Western blotting was also performed to detect Siah2 and AR protein concentrations and co-immunoprecipitation to detect interactions of Siah2 and AR, NCoR1 and AR, and p300 and AR. JS-K inhibited proliferation and induced apoptosis in prostate cancer cells. JS-K increased p53 and Mdm2 concentrations and regulated the caspase cascade reaction-associated protein concentrations. JS-K inhibited transcription of AR target genes and down-regulated PSA protein concentrations. JS-K inhibited Siah2 interactions and also inhibited the ubiquitination of AR. With further investigation, JS-K was found to stabilize AR and NCoR1 interactions and diminish AR and p300 interactions. The present results suggested that JS-K might have been able to inhibit proliferation and induce apoptosis via regulation of the ubiquitin-proteasome degradation pathway, which represented a promising platform for the development of new compounds for PCa treatments.

  2. ANALISIS POSITIONING RESTORAN CEPAT SAJI

    Directory of Open Access Journals (Sweden)

    Osa Omar Sharif

    2017-04-01

    Full Text Available Penelitian ini bertujuan untuk meneliti positioning restoran cepat saji McDonald's, Kentucky Fried Chicken, California Fried Chicken, A&W, dan Texas Chicken. Penelitian dilakukan di Kota Bandung dengan mengambil sebanyak 400 responden. Analisis yang digunakan dalam penelitian ini adalah analisis multidimensional scaling, analisis memberikan gambaran positioning dari restoran cepat saji yang ditampilkan dalam perceptual map. Restoran cepat saji yang memiliki layanan paling baik adalah McD dan yang memiliki layanan paling buruk adalah CFC. Restoran cepat saji yang memiliki rasa makanan paling enak adalah McD dan yang memiliki rasa makanan tidak enak adalah CFC. KFC dinilai paling ideal karena selalu berhasil menduduki peringkat satu dan dua jika dilihat dari sudut pandang restoran cepat saji yang lain. Pesaing terdekat McD adalah KFC. McD mendapatkan ranking pertama dari segi atribut layanan, kebersihan, variasi makanan, dan rasa makanan. Dengan posisi seperti ini McD seharusnya tetap menjaga kualitas layanan, kebersihan, variasi makanan, dan rasa makanan agar konsumen tetap memilih untuk datang ke McD. KFC sebaiknya tetap menjaga suasana yang membuat konsumen nyaman akan suasana di dalam atau diluar restoran

  3. Origin of irradiations by ionizing radiations

    International Nuclear Information System (INIS)

    Metivier, H.

    1998-01-01

    Irradiations by ionizing radiations proceed from two main sources: the natural radiations from the environment and the sources of 'human' origin, i.e. linked with modern technology. In most countries the irradiation by natural sources remains the most important. The irradiations for medical purposes comes in second position and depends on the degree of technological evolution of the country, and in the last position are the irradiations linked with nuclear industry. The inventory of these irradiations is regularly updated by the Scientific Committee of the United Nations for the study of ionizing radiation effects (UNSCEAR). In France the mean individual irradiation due to natural radioactivity is of 2 mSv per year of efficient dose and can vary with a factor 3 from one region to the other. Irradiation of medical diagnosis origin is of about 1 mSv per year. This paper presents successively: the natural irradiation sources (cosmic radiation, cosmic rays and cosmogenic radionuclides, the Earth's radiations, primary radionuclides and radon), the natural sources modified by the technology (extraction industries, fossil fuels and phosphated ores, aerial transports and space activities, consumer products), the irradiation sources of technological origin (nuclear weapons, electric power production, major accidents, occupational irradiations), and the medical irradiations (diagnosis techniques, radiology, nuclear medicine and therapeutic uses). (J.S.)

  4. Materials aging: first predictive modeling of iron under irradiation

    International Nuclear Information System (INIS)

    Anon.

    2005-01-01

    Researchers from the CEA-Bruyeres-le-Chatel have been able to quantitatively foresee for the very first time the evolution of irradiation defects inside a structural material. Their results, obtained with iron, will contribute to better understand the aging of the materials of today's nuclear power plants and of future nuclear systems. Short paper. (J.S.)

  5. Web development with MongoDB and Node.js

    CERN Document Server

    Krol, Jason

    2014-01-01

    This book is designed for developers of any skill level that want to get up and running using Node.js and MongoDB to build full featured web applications. A basic understanding of JavaScript and HTML is the only requirement for this book.

  6. Effects of JS-K, a novel anti-cancer nitric oxide prodrug, on gene expression in human hepatoma Hep3B cells.

    Science.gov (United States)

    Dong, Ray; Wang, Xueqian; Wang, Huan; Liu, Zhengyun; Liu, Jie; Saavedra, Joseph E

    2017-04-01

    JS-K is a novel anticancer nitric oxide (NO) prodrug effective against a variety of cancer cells, including the inhibition of AM-1 hepatoma cell growth in rats. To further evaluate anticancer effects of JS-K, human hepatoma Hep3B cells were treated with JS-K and the compound control JS-43-126 at various concentrations (0-100μM) for 24h, and cytotoxicity was determined by the MTS assay. The compound control JS-43-126 was not cytotoxic to Hep3B cells at concentrations up to 100μM, while the LC 50 for JS-K was about 10μM. To examine the molecular mechanisms of antitumor effects of JS-K, Hep3B cells were treated with 1-10μM of JS-K for 24h, and then subjected to gene expression analysis via real time RT-PCR and protein immunostain via confocal images. JS-K is a GST-α targeting NO prodrug, and decreased immunostaining for GST-α was associated with JS-K treatment. JS-K activated apoptosis pathways in Hep3B cells, including induction of caspase-3, caspase-9, Bax, TNF-α, and IL-1β, and immunostaining for caspase-3 was intensified. The expressions of thrombospondin-1 (TSP-1) and the tissue inhibitors of metalloproteinase-1 (TIMP-1) were increased by JS-K at both transcript and protein levels. JS-K treatment also increased the expression of differentiation-related genes CD14 and CD11b, and depressed the expression of c-myc in Hep3B cells. Thus, multiple molecular events appear to be associated with anticancer effects of JS-K in human hepatoma Hep3B cells, including activation of genes related to apoptosis and induction of genes involved in antiangiogenesis and tumor cell migration. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  7. IDENTIFIKASI MISKONSEPSI SISWA SMP PADA KONSEP FOTOSINTESIS MELALUI ANALISIS GAMBAR

    Directory of Open Access Journals (Sweden)

    Devi Ariandini

    2014-01-01

    Full Text Available Tujuan dari penelitian ini adalah untuk mengidentifikasi miskonsepsi siswa dengan analisis menggambar. Tiga puluh empat siswa di kelas 8 di sekolah menengah pertama digunakan sebagai subyek dalam penelitian ini. Teknik sampel menggunakan teknik purposive sampling. Data yang diperlukan untuk penelitian ini dikumpulkan melalui kuesioner, menggambar analisis rubrik, dan wawancara. Identifikasi Kesalahpahaman ditentukan dengan menggambar siswa berdasarkan menggambar kriteria klasifikasi oleh Kose (2008. Siswa diperintahkan untuk menarik tentang konsep fotosintesis setelah proses pembelajaran. Gambar siswa dianalisis dengan rubrik dan setelah itu mereka diwawancarai. Hasil penelitian menunjukkan tidak semua tingkat kriteria menggambar dari tingkat 1 sampai 5 diidentifikasi. Dari hasil analisa, gambar paling banyak ditemukan adalah pada tingkat 4. Gambar pada tingkat 4 dikategorikan sebagai gambar lengkap konsep fotosintesis dan tidak ada kesalahpahaman ditemukan. Berdasarkan gambar mereka, ada siswa 2,9% diidentifikasi yang diselenggarakan kesalahpahaman. Ada perbedaan jumlah siswa yang diadakan kesalahpahaman antara gambar hasil analisis dan hasil wawancara. Dari hasil wawancara, ada siswa 35,2% dimiliki kesalahpahaman, lebih dari menggambar hasil analisis. Ini berarti bahwa identifikasi kesalahpahaman melalui analisis gambar tidak efektif. Kesalahpahaman siswa yang paling sering terjadi pada konsep fotosintesis adalah tempat berlangsungnya fotosintesis. Faktor yang membuat kesalahpahaman siswa yaitu karena siswa itu sendiri dan lingkungannya. Kata Kunci: fotosintesis, kesalahpahaman, konsep, menggambar analisis

  8. RESTful web API design with Node.js

    CERN Document Server

    Bojinov, Valentin

    2015-01-01

    If you are a web developer wanting to enrich your development skills to create scalable, server-side, RESTful applications based on the Node.js platform, this book is for you. You also need to be aware of HTTP communication concepts and should have a working knowledge of JavaScript. Knowledge of REST would be an added advantage but is definitely not a necessity.

  9. Hydrolysis and photolysis of diacylhydrazines-type insect growth regulator JS-118 in aqueous solutions under abiotic conditions.

    Science.gov (United States)

    Hu, J-Y; Liu, C; Zhang, Y-C; Zheng, Z-X

    2009-05-01

    JS-118 is a diacylhydrazines-type insect growth regulator which is now used extensively in China. The hydrolysis and photolysis of the pesticide JS-118 in aqueous solutions have been assessed under natural and controlled conditions in this project. Hydrolysis experimental results show that JS-118 is quite stable in aqueous solutions in dark, with no significant variations be observed in degradation under various conditions. Abiotic hydrolysis is relatively unimportant compared to photolysis. The rate of photodecomposition of JS-118 in aqueous solutions follows first-order kinetics both in UV radiation and natural sunlight. The degradation rates are faster under UV light than sunlight, with the half-lives (t (1/2) = ln2/k) of 6.00-10.85 min and 6.63-10.16 day, respectively. Under UV light, two major photoproducts are detected, and tentatively identified according to HPLC-MS spectral information as N-t-butyl-N-(3,5-dimethylbenzoyl) and 3,7-dimethyl-benzoatedihydrofuran. The corresponding photolysis pathways of JS-118 are also proposed. The results obtained indicate that direct photoreaction is an important dissipation pathway of JS-118 in natural water systems.

  10. Getting started with PhantomJS

    CERN Document Server

    Beltran, Aries

    2013-01-01

    The book will follow aA standard tutorial approach, and will beas a complete guide detailing the major aspects of PhantomJS with particular focus on Website website Testingtesting.This book is written forIf you are a JavaScript developers who are is interested in developing applications that interact with various web services, and doing that using a headless browser, then this book is ideal for you. This book iswill also be good for you if you are planning to create a headless browser testing for your web application. Basic understanding of JavaScript is assumed.

  11. Instant Backbone.js application development

    CERN Document Server

    Hunter, Thomas

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. This book is a practical, step-by-step tutorial that will teach you to build Backbone.js applications quickly and efficiently.This book is targeted towards developers. It is assumed that you have at least a basic understanding of JavaScript and jQuery selectors. If you are interested in building dynamic Single Page Applications that interact heavily with a backend server, then this is the book for you.

  12. The Nitric Oxide Prodrug JS-K Induces Ca(2+)-Mediated Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells.

    Science.gov (United States)

    Liu, Ling; Wang, Dongmei; Wang, Jiangang; Wang, Shuying

    2016-04-01

    Hepatocellular carcinoma is one of the most common and deadly forms of human malignancies. JS-K, O(2)-(2, 4-dinitrophenyl) 1-[(4-ethoxycarbonyl) piperazin-1-yl] diazen-1-ium-1, 2-diolate, has the ability to induce apoptosis of tumor cell lines. In the present study, JS-K inhibited the proliferation of HepG2 cells in a time- and concentration-dependent manner and significantly induced apoptosis. JS-K enhanced the ratio of Bax-to-Bcl-2, released of cytochrome c (Cyt c) from mitochondria and the activated caspase-9/3. JS-K caused an increasing cytosolic Ca(2+) and the loss of mitochondrial membrane potential. Carboxy-PTIO (a NO scavenger) and BAPTA-AM (an intracellular Ca(2+) chelator) significantly blocked an increasing cytosolic Ca(2+) in JS-K-induced HepG2 cells apoptosis, especially Carboxy-PTIO. Meanwhile, Carboxy-PTIO and BAPTA-AM treatment both attenuate JS-K-induced apoptosis through upregulation of Bcl-2, downregulation of Bax, reduction of Cyt c release from mitochondria to cytoplasm and inactivation of caspase-9/3. In summary, JS-K induced HepG2 cells apoptosis via Ca(2+)/caspase-3-mediated mitochondrial pathway. © 2015 Wiley Periodicals, Inc.

  13. Mechanism of action for the cytotoxic effects of the nitric oxide prodrug JS-K in murine erythroleukemia cells.

    Science.gov (United States)

    Kaczmarek, Monika Z; Holland, Ryan J; Lavanier, Stephen A; Troxler, Jami A; Fesenkova, Valentyna I; Hanson, Charlotte A; Cmarik, Joan L; Saavedra, Joseph E; Keefer, Larry K; Ruscetti, Sandra K

    2014-03-01

    The nitric oxide (NO) prodrug JS-K, a promising anti-cancer agent, consists of a diazeniumdiolate group necessary for the release of NO as well as an arylating ring. In this study, we research the mechanism by which JS-K kills a murine erythroleukemia cell line and determine the roles of NO and arylation in the process. Our studies indicate that JS-K inhibits the PI 3-kinase/Akt and MAP kinase pathways. This correlates with the activation of the tumor suppressor FoxO3a and increased expression of various caspases, leading to apoptosis. The arylating capability of JS-K appears to be sufficient for inducing these biological effects. Overall, these data suggest that JS-K kills tumor cells by arylating and inactivating signaling molecules that block the activation of a tumor suppressor. Published by Elsevier Ltd.

  14. Instant dependency management with RequireJS how-to

    CERN Document Server

    Franko, Greg

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks.A concise guide that delivers immediate results with practical recipes on customizing your projects.This book is for intermediate to advanced JavaScript developers who are interested in learning more about AMD specification and RequireJS.

  15. Analisis Tingkat Kepentingan Dan Kinerja Layanan Automated Teller Machine (Atm) Bank Mandiri

    OpenAIRE

    Setiawati, Lenny; Sugiharto, Toto

    2008-01-01

    Penelitian ini ditujukan untuk menganalisis tingkat kepentingan dan kinerja layananATM Bank Mandiri. Analisis Servqual yang terdiri atas dimensi tangible, realibility,responsiveness, assurance,dan empathy digunakan untuk menganalisis kinerjalayanan ATM. Sementara itu, Customer Satisfaction Index dan ImportancePerformance Analysis yang terdiri atas analisis kuadran dan analisis kesenjangandigunakan untuk menginvestigasi kepuasan pelanggan dan untuk mengidentifikasikandimensi layanan yang kiner...

  16. ANALISIS SPASIAL KEJADIAN DEMAM BERDARAH DENGUE BERDASARKAN KEPADATAN PENDUDUK

    Directory of Open Access Journals (Sweden)

    Agcrista Permata Kusuma

    2016-01-01

    Full Text Available Abstrak Puskesmas Kedungmundu merupakan wilayah endemis DBD dengan kasus yang tinggi. Diperlukan upaya dalam menentukan kebijakan strategi pengendalian vektor secara efektif dan efisien. Analisis spasial dalam SIG dapat digunakan untuk mengetahui pola penyebaran dan daerah potensi penularan DBD. Jenis penelitian ini adalah penelitian deskriptif analitik menggunakan pendekatan cross sectional. Teknik pengambilan sampel menggunakan sampel wilayah memperhatikan proporsi sampel dengan jumlah sampel 146 responden. Pengambilan titik koordinat menggunakan GPS. Analisis data menggunakan analisis univariat dan analisis spasial. Hasil perhitungan statistik spasial ANN diperoleh nilai Z-score = -11,054 terdapat pola spasial kasus DBD di wilayah kerja Puskesmas Kedungmundu. Nilai ANN = 0,52 < 1, artinya pola penyebaran kejadian DBD yang terjadi adalah berkerumun. Kesimpulan dalam penelitian ini sebaran kasus DBD memiliki keterkaitan secara spasial dengan kepadatan penduduk. Abstract Kedungmundu PHC is an endemich region with a high case. Be required to determine policy of vector control strategies effectively and efficiently. Spatial analsys in GIS can be used to determine the pattern of distribution and areas of DHF potential transmission. The type this research was analysis descriptive with cross sectional approach. The sampling technique used a sample area of attention to the proportion of the sample with 146 respondents of total sample. Capturing the coordinates used GPS. Data analisys used univariat and spatial analisys. Result of ANN obtained a Z-score= -11,054, there was a spatial pattern of dengue cases in Kedungmundu PHC. ANN value = 0,52 < 1, it meant that the pattern of DHF distribution was clustered. The conclution of this research was DHF distribution cases has spatial correlation with density population.

  17. Unit testing of AngularJS : A look into writing tests for web application

    OpenAIRE

    Karttunen, Joel

    2016-01-01

    This task was assigned by Protacon Solutions Oy with the objective set to study and implement unit testing in AngularJS JavaScript framework as part of the development process of the customer’s application. The thesis focuses on studying the AngularJS framework and if and how its design philosophy complements the unit testing principles. The focus was on studying unit testing via developing unit tests iteratively onto the application created beforehand. The tests were created with Jas...

  18. ANALISIS KESELAMATAN TERMOHIDROLIK BULK SHIELDING REAKTOR KARTINI

    Directory of Open Access Journals (Sweden)

    Azizul Khakim

    2015-10-01

    Full Text Available ABSTRAK ANALISIS KESELAMATAN TERMOHIDROLIK BULK SHIELDING REAKTOR KARTINI. Bulk shielding merupakan fasilitas yang terintegrasi dengan reaktor Kartini yang berfungsi sebagai penyimpanan sementara bahan bakar bekas. Fasilitas ini merupakan fasilitas yang termasuk dalam struktur, sistem dan komponen (SSK yang penting bagi keselamatan. Salah satu fungsi keselamatan dari sistem penanganan dan penyimpanan bahan bakar adalah mencegah kecelakaan kekritisan yang tak terkendali dan membatasi naiknya temperatur bahan bakar. Analisis keselamatan paling kurang harus mencakup analisis keselamatan dari sisi neutronik dan termo hidrolik Bulk shielding. Analisis termo hidrolik ditujukan untuk memastikan perpindahan panas dan proses pendinginan bahan bakar bekas berjalan baik dan tidak terjadi akumulasi panas yang mengancam integritas bahan bakar. Code tervalidasi PARET/ANL digunakan untuk analisis pendinginan dengan mode konveksi alam. Hasil perhitungan menunjukkan bahwa mode pendinginan konvekasi alam cukup memadai dalam mendinginkan panas sisa tanpa mengakibatkan kenaikan temperatur bahan bakar yang signifikan. Kata kunci: Bulk shielding, bahan bakar bekas, konveksi alam, PARET.   ABSTRACT THERMAL HYDRAULIC SAFETY ANALYSIS OF BULK SHIELDING KARTINI REACTOR. Bulk shielding is an integrated facility to Kartini reactor which is used for temporary spent fuels storage. The facility is one of the structures, systems and components (SSCs important to safety. Among the safety functions of fuel handling and storage are to prevent any uncontrolable criticality accidents and to limit the fuel temperature increase. Safety analyses should, at least, cover neutronic and thermal hydraulic calculations of the bulk shielding. Thermal hydraulic analyses were intended to ensure that heat removal and the process of the spent fuels cooling takes place adequately and no heat accumulation that challenges the fuel integrity. Validated code, PARET/ANL was used for analysing the

  19. Analisis Semiotik Sajak Bulang Cahaya

    Directory of Open Access Journals (Sweden)

    Junaidi Junaidi

    2014-11-01

    Full Text Available Penelitian ini bertujuan menggali makna tanda yang terdapat dalam sajak Bulang Cahaya karya Rida K Liamsi. Untuk menggali makna itu, pendekatan analisis semiotik Roland Barthes digunakan. Hasil penelitian menunjukkan bahwa sajak ini berisi tanda-tanda bersumber dari kosa kata Melayu lama. Sajak ini juga berisi simbol-simbol yang berkaitan dengan kehidupan orang Melayu. Penggunaan kata-kata Melayu lama dan simbol Melayu memperkuat setting Melayu dalam sajak ini. Analisis makna menunjukkan bahwa seseorang merasakan kedukaan sangat mendalam ketika cintanya harus berakhir, tetapi ia terus merasakan kerinduan dengan kekasihnya yang telah pergi. Mitos cinta yang terdapat dalam pusinya adalah orang tahu bahwa putus cinta itu menyakitkan tetapi orang tetap saja jatuh cinta.

  20. Nitric oxide prodrug JS-K inhibits ubiquitin E1 and kills tumor cells retaining wild-type p53.

    Science.gov (United States)

    Kitagaki, J; Yang, Y; Saavedra, J E; Colburn, N H; Keefer, L K; Perantoni, A O

    2009-01-29

    Nitric oxide (NO) is a major effector molecule in cancer prevention. A number of studies have shown that NO prodrug JS-K (O(2)-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate) induces apoptotic cell death in vitro and in vivo, indicating that it is a promising new therapeutic for cancer. However, the mechanism of its tumor-killing activity remains unclear. Ubiquitin plays an important role in the regulation of tumorigenesis and cell apoptosis. Our earlier report has shown that inactivation of the ubiquitin system through blocking E1 (ubiquitin-activating enzyme) activity preferentially induces apoptosis in p53-expressing transformed cells. As E1 has an active cysteine residue that could potentially interact with NO, we hypothesized that JS-K could inactivate E1 activity. E1 activity was evaluated by detecting ubiquitin-E1 conjugates through immunoblotting. JS-K strikingly inhibits the ubiquitin-E1 thioester formation in cells in a dose-dependent manner with an IC(50) of approximately 2 microM, whereas a JS-K analog that cannot release NO did not affect these levels in cells. Moreover, JS-K decreases total ubiquitylated proteins and increases p53 levels, which is mainly regulated by ubiquitin and proteasomal degradation. Furthermore, JS-K preferentially induces cell apoptosis in p53-expressing transformed cells. These findings indicate that JS-K inhibits E1 activity and kills transformed cells harboring wild-type p53.

  1. JS-III-49, a hydroquinone derivative, exerts anti-inflammatory activity by targeting Akt and p38.

    Science.gov (United States)

    Yi, Young-Su; Kim, Mi-Yeon; Cho, Jae Youl

    2017-05-01

    Since previous studies have reported that hydroquinone (HQ) exerted immunosuppressive and anti-inflammatory activity, various HQ derivatives have been synthesized and their biological activities investigated. In this study, we explored the anti-inflammatory activity of JS-III-49, a novel HQ derivative, in macrophage-mediated inflammatory responses. JS-III-49 suppressed the production of the inflammatory mediators nitric oxide (NO) and prostaglandin E 2 (PGE 2 ) and down-regulated the mRNA expression of the inflammatory enzymes cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) as well as the expression of the pro-inflammatory cytokines interleukin-6 (IL-6) and IL-1b without cytotoxicity in LPS-stimulated RAW264.7 cells. JS-III-49 inhibited nuclear translocation of the NF-kB transcription factors p65 and p50 by directly targeting Akt, an upstream kinase of the NF-kB pathway, in LPS-stimulated RAW264.7 cells. However, JS-III-49 did not directly inhibit the kinase activities of Src and Syk, which are upstream kinases of Akt, in LPS-stimulated RAW264.7 cells. Moreover, JS-III-49 suppressed the nuclear translocation of c-Fos, one of the components of AP-1, by specifically targeting p38, an upstream mitogen-activated protein kinase (MAPK) in the AP-1 pathway in LPS-stimulated RAW264.7 cells. These results suggest that JS-III-49 plays an anti-inflammatory role in LPS-stimulated macrophages by targeting Akt and p38 in the NF-kB and AP-1 pathways, respectively.

  2. BioCircos.js: an interactive Circos JavaScript library for biological data visualization on web applications.

    Science.gov (United States)

    Cui, Ya; Chen, Xiaowei; Luo, Huaxia; Fan, Zhen; Luo, Jianjun; He, Shunmin; Yue, Haiyan; Zhang, Peng; Chen, Runsheng

    2016-06-01

    We here present BioCircos.js, an interactive and lightweight JavaScript library especially for biological data interactive visualization. BioCircos.js facilitates the development of web-based applications for circular visualization of various biological data, such as genomic features, genetic variations, gene expression and biomolecular interactions. BioCircos.js and its manual are freely available online at http://bioinfo.ibp.ac.cn/biocircos/ rschen@ibp.ac.cn Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  3. Membandingkan Tingkat Kemiripan Rekaman Voice Changer Menggunakan Analisis Pitch, Formant dan Spectogram

    Directory of Open Access Journals (Sweden)

    Ahmad Subki

    2018-02-01

    Full Text Available Audio forensik merupakan salah satu ilmu yang mnyandingkan antara ilmu pengetahuan dan metode ilmiah dalam proses analisis rekaman suara untuk membantu dan mendukung pengungkapan suatu tindak kejahatan yang diperlukan dalam proses persidangan. Undang-undang ITE No.19 Tahun 2016 menyebutkan bahwa rekaman suara merupakan salah satu alat bukti digital yang sah dan dapat digunakan sebagai penguat dakwaan. Rekaman suara yang merupakan barang bukti digital sangatlah mudah dan rentan dimanipulasi, baik secara sengaja maupun tidak disengaja. Pada penelitian ini dilakukan analisis terkait tingkat kemiripan antara rekaman suara voice changer dengan rekaman suara asli menggunakan analisis pitch, formant dan spectogram, rekaman suara yang dianalisis ada dua jenis rekaman suara yaitu suara laki-laki dan suara perempuan. Rekaman suara voice changer  dan rekaman suara asli, diekstrak menggunakan tools praat kemudian informasi yang diperoleh dianalisis dengan analisis statistik pitch, formant dan spectrogrammenggunakan tools gnumeric. Penelitian ini menghasilkan bahwa analisis rekaman suara voice changer dengan rekaman suara asli dapat menggunakan analisis statistik pitch, formant dan spectrogram, rekaman suara voice changer A memiliki tingkat kemiripan yang paling tinggi dengan rekaman suara asli pada posisi low pitch, sedangkan voice changer yang lain lebih sulit untuk diidentifikasi.

  4. Summary of Skoda JS rod drop measurements analysis

    International Nuclear Information System (INIS)

    Svarny, J.; Krysl, V.

    1999-01-01

    A summary is presented of the Skoda JS rod drop reactivity measurements analysis provided during last two years based on control rod worth measurements by the outer ion chambers. Standard analysis based on comparisons of dynamics macrocode MOBY-DICK-SK and experimental data is extended to the 8-th group delayed neutron structure and new features of rod drop process are investigated. (author)

  5. JS-K has Potent Anti-Angiogenic Activity in vitro and Inhibits Tumor Angiogenesis in a Multiple Myeloma Model in vivo

    Science.gov (United States)

    Kaur, Gurmeet; Kiziltepe, Tanyel; Anderson, Kenneth C.; Kutok, Jeffery L.; Jia, Lee; Boucher, Kenneth M.; Saavedra, Joseph E.; Keefer, Larry K.; Shami, Paul J.

    2009-01-01

    Glutathione S-Transferases (GST) play an important role in multidrug resistance and are upregulated in multiple cancers. We have designed a prodrug class that releases NO on metabolism by GST. O2-(2,4-Dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K, a member of this class) has potent anti-neoplastic activity. We studied the effect of JS-K on angiogenesis. JS-K inhibited the proliferation of HUVEC’s with a 50% inhibitory concentration (IC50) of 0.432, 0.466, and 0.505 µM at 24, 48, and 72 hours, respectively. In the cord formation assay, JS-K led to a decrease in the number of cord junctions and cord length with an IC50 of 0.637 and 0.696 µM, respectively. JS-K inhibited cell migration at 5 hours using VEGF as a chemoattractant. Migration inhibition occurred with an IC50 of 0.493 µM. In the chick aortic ring assay using VEGF or FGF-b for vessel growth stimulation, 0.5 µM JS-K completely inhibited vessel growth. JS-K inhibited tumor angiogenesis in vivo in NIH III mice implanted subcutaneously with OPM1 multiple myeloma cells. JS-K is a potent inhibitor of angiogenesis in vitro and tumor vessel growth in vivo. As such, it establishes a new class of anti-neoplastic agents that target the malignant cells directly as well as their microenvironment. PMID:20723011

  6. Studies on Nitrobenzene Metabolism by a Comamonas sp. Strain JS7651

    National Research Council Canada - National Science Library

    Gibson, David

    2000-01-01

    .... The nitrobenzene dioxygenase enzyme system shares high amino acid homology with other identified nitroarene dioxygenase enzymes, in particular the 2-nitrotoluene dioxygenase system from Pseudomonas sp. strain JS42...

  7. Activation of Pathogenesis-related Genes by the Rhizobacterium, Bacillus sp. JS, Which Induces Systemic Resistance in Tobacco Plants.

    Science.gov (United States)

    Kim, Ji-Seong; Lee, Jeongeun; Lee, Chan-Hui; Woo, Su Young; Kang, Hoduck; Seo, Sang-Gyu; Kim, Sun-Hyung

    2015-06-01

    Plant growth promoting rhizobacteria (PGPR) are known to confer disease resistance to plants. Bacillus sp. JS demonstrated antifungal activities against five fungal pathogens in in vitro assays. To verify whether the volatiles of Bacillus sp. JS confer disease resistance, tobacco leaves pre-treated with the volatiles were damaged by the fungal pathogen, Rhizoctonia solani and oomycete Phytophthora nicotianae. Pre-treated tobacco leaves had smaller lesion than the control plant leaves. In pathogenesis-related (PR) gene expression analysis, volatiles of Bacillus sp. JS caused the up-regulation of PR-2 encoding β-1,3-glucanase and acidic PR-3 encoding chitinase. Expression of acidic PR-4 encoding chitinase and acidic PR-9 encoding peroxidase increased gradually after exposure of the volatiles to Bacillus sp. JS. Basic PR-14 encoding lipid transfer protein was also increased. However, PR-1 genes, as markers of salicylic acid (SA) induced resistance, were not expressed. These results suggested that the volatiles of Bacillus sp. JS confer disease resistance against fungal and oomycete pathogens through PR genes expression.

  8. PhoneGap and AngularJS for cross-platform development

    CERN Document Server

    Liang, Yuxian Eugene

    2014-01-01

    This book is intended for people who are not familiar with AngularJS and who want to take their PhoneGap development skills further by developing apps using different JavaScript libraries. People with some knowledge of PhoneGap, HTML, CSS, and JavaScript will find this book immediately useful.

  9. Status of food irradiation in Brazil

    International Nuclear Information System (INIS)

    Kikuchi, O.K.

    1996-01-01

    Research on food irradiation in Brazil started in 1968 at the Center of Nuclear Energy for Agriculture (CENA), Piracicaba, Sao Paulo. At the Institute of Nuclear and Energy Research (IPEN-CNEN/SP), Sao Paulo, Sao Paulo, research on detection of irradiated foods is in progress. In 1973, the Brazilian government established a regulation about food irradiation. Nowadays, the products authorized to be irradiated are: rice, poultry, fish and fish products, potatoes, onions, avocados, persimmons, pineapples, wheat flour, maize, beans, spices, tomatoes, guavas, oranges, lemons, strawberries, mangoes, melons and papayas. The other recommended products to be approved in the future are: acerolas, apples, beans (dose > 1 kGy), beef, blueberries, cherries, cheeses, coffee, figs, fresh guaranas, garlics, grapefruits, grapes, mushrooms, nuts and pork. Today, there is only one commercial facility for irradiation services in the country, the Empresa Brasileira de Radiacoes Ltda. (EMBRARAD). This company operates a Nordion JS-7500 irradiator, with a present activity of about 1,000 kCi, designed for sterilizing medical devices. It also irradiates spices, dried foods, gemstones, cosmetics, wood and raw materials for pharmaceuticals. The plant operates 24 hours a day and the spices and dried foods represent 15% of the business. Powder of guarana seeds is irradiated also for exportation. There are two other commercial facilities for radiation sterilization in Brazil, operating exclusively for their own production. (J.P.N.)

  10. JS-K has potent anti-angiogenic activity in vitro and inhibits tumour angiogenesis in a multiple myeloma model in vivo.

    Science.gov (United States)

    Kiziltepe, Tanyel; Anderson, Kenneth C; Kutok, Jeffery L; Jia, Lee; Boucher, Kenneth M; Saavedra, Joseph E; Keefer, Larry K; Shami, Paul J

    2010-01-01

    Glutathione S-transferases (GSTs) play an important role in multidrug resistance and are upregulated in multiple cancers. We have designed a prodrug class that releases nitric oxide on metabolism by GST. O(2)-(2,4-Dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K, a member of this class) has potent antineoplastic activity. We studied the effect of JS-K on angiogenesis in human umbilical vein endothelial cells (HUVECs), OPM1 multiple myeloma cells, chick aortic rings and in mice. JS-K inhibited the proliferation of HUVECs with a 50% inhibitory concentration (IC50) of 0.432, 0.466 and 0.505 microm at 24, 48 and 72 h, respectively. In the cord formation assay, JS-K led to a decrease in the number of cord junctions and cord length with an IC50 of 0.637 and 0.696 microm, respectively. JS-K inhibited cell migration at 5 h using VEGF as a chemoattractant. Migration inhibition occurred with an IC50 of 0.493 microm. In the chick aortic ring assay using VEGF or FGF-2 for vessel growth stimulation, 0.5 microm JS-K completely inhibited vessel growth. JS-K inhibited tumour angiogenesis in vivo in NIH III mice implanted subcutaneously with OPM1 multiple myeloma cells. JS-K is a potent inhibitor of angiogenesis in vitro and tumour vessel growth in vivo. As such, it establishes a new class of antineoplastic agent that targets the malignant cells directly as well as their microenvironment.

  11. ANALISIS PENERAPAN 8 STANDAR NASIONAL PENDIDIKAN PADA SMP NEGERI 2 DOLOPO KABUPATEN MADIUN

    Directory of Open Access Journals (Sweden)

    Luki Eko Cahyono

    2015-10-01

    Penelitian ini menggunakan desain penelitian Deskriptif Kualitatif. Jenis penelitian adalah studi kasus. Data yang digunakan adalah data Primer. Teknik pengumpulan data yang digunakan adalah wawancara dan dokumentasi. Teknik keabsahan data adalah Triangulasi Sumber dan teknik analisis data yang digunakan adalah pendekatan Strengths, Weakness, Opportunities, dan Threats (Analisis SWOT. Kesimpulan penelitian ini adalah (1 Hasil analisis Strenght (Kekuatan adalah sekolah sudah merencanakan, melaksanakan dan mengevaluasi sebagian besar indikator dalam pemenuhan Standar Nasional Pendidikan sehingga meningkatkan mutu pendidikan sekolah. (2 Hasil analisis Weakness (kelemahan adalah keterbatasan anggaran dana dan sumber daya manusia baik peserta didik, pendidik, maupun tenaga kependidikan dalam pemenuhan seluruh unsur Standar Nasional Pendidikan. (3 Hasil analisis Opportunities (peluang adalah Pemberian workshop dan pelatihan kepada pendidik dan tenaga kependidikan meningkatkan kualitas pendidikan sekolah, dan perencanaan, pelaksanaan pembiayaan serta evaluasi penganggaran yang baik memberikan dampak positif terhadap semua unsur operasional sekolah maupun sarana prasarana sekolah. (4 Hasil analisis Threats (Tantangan adalah perencanaan, sosialisasi, pelaksanaan dan evaluasi serta tindak lanjut yang tidak dijalankan dengan manajemen yang baik dalam upaya pemenuhan Standar Nasional Pendidikan akan menghambat peningkatan kualitas pendidikan sekolah. (5 Hasil penerapan Standar Nasional Pendidikan pada SMP Negeri 2 Dolopo menggunakan analisis SWOT menunjukkan bahwa Kekuatan lebih besar daripada Kelemahan dan Peluang lebih besar dari Ancaman, yang berarti Standar Nasional Pendidikan telah terpenuhi dan menghasilkan Akreditasi Sekolah nilai A.

  12. Physiological and proteomic analysis of plant growth enhancement by the rhizobacteria Bacillus sp. JS.

    Science.gov (United States)

    Kim, Ji Seong; Lee, Jeong Eun; Nie, Hualin; Lee, Yong Jae; Kim, Sun Tae; Kim, Sun-Hyung

    2018-02-01

    In this study, the effects of the plant growth-promoting rhizobacterium (PGPR), Bacillus sp. JS on the growth of tobacco (Nicotiana tabacum 'Xanthi') and lettuce (Lactuca sativa 'Crispa'), were evaluated by comparing various growth parameters between plants treated with the bacterium and those exposed to water or nutrient broth as control. In both tobacco and lettuce, fresh weight and length of shoots were increased upon exposure to Bacillus sp. JS. To explain the overall de novo expression of plant proteins by bacterial volatiles, two-dimensional gel electrophoresis was performed on samples from PGPR-treated tobacco plants. Our results showed that chlorophyll a/b binding proteins were significantly up-regulated, and total chlorophyll content was also increased. Our findings indicate the potential benefits of using Bacillus sp. JS as a growth-promoting factor in agricultural practice, and highlight the need for further research to explore these benefits.

  13. Introduktion til programmering (P5/JS) light version 1.0

    DEFF Research Database (Denmark)

    Bjerre, Anne

    2015-01-01

    Undervisningsmateriale til begynderprogrammering. Materialet er baseret på P5, som er et grafisk baseret Javascript-bibliotek. Applikationen er en "light"-udgave af Introduktion til programmering (P5/JS) version 1.0. Afsnittet om transformationer er udeladt, og resten af applikationen modificeret...

  14. Oral JS-38, a metabolite from Xenorhabdus sp., has both anti-tumor activity and the ability to elevate peripheral neutrophils.

    Science.gov (United States)

    Liu, Min-Yu; Xiao, Lin; Chen, Geng-Hui; Wang, Yong-Xiang; Xiong, Wei-Xia; Li, Fei; Liu, Ying; Huang, Xiao-Ling; Deng, Yi-Fang; Zhang, Zhen; Sun, Hai-Yan; Liu, Quan-Hai; Yin, Ming

    2014-10-01

    JS-38 (mitothiolore), a synthetic version of a metabolite isolated from Xenorhabdus sp., was evaluated for its anti-tumor and white blood cell (WBC) elevating activities. These anti-proliferative activities were assessed in vitro using a panel of ten cell lines. The anti-tumor activities were tested in vivo using B16 allograft mouse models and xenograft models of A549 human lung carcinoma and QGY human hepatoma in nude mice. The anti-tumor interactions of JS-38 and cyclophosphamide (CTX) or 5-fluorouracil (5-Fu) were studied in a S180 sarcoma model in ICR mice. Specific stimulatory effects were determined on peripheral neutrophils in normal and CTX- and 5-Fu-induced neutropenic mice. The IC50 values ranged from 0.1 to 2.0 μmol·L(-1). JS-38 (1 μmol·L(-1)) caused an increase in A549 tumor cell apoptosis. Multi-daily gavage of JS-38 (15, 30, and 60 mg·kg(-1)·d(-1)) inhibited in vivo tumor progression without a significant effect on body weight. JS-38 additively enhanced the in vivo anti-tumor effects of CTX or 5-Fu. JS-38 increased peripheral neutrophil counts and neutrophil rates in normal BALB/c mice almost as effectively as granulocyte colony-stimulating factor (G-CSF). In mice with neutropenia induced by CTX or 5-Fu, JS-38 rapidly restored neutrophil counts. These results suggest that JS-38 has anti-tumor activity, and also has the ability to increase peripheral blood neutrophils. Copyright © 2014 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

  15. Variations in glycoprotein B contribute to immunogenic difference between PRV variant JS-2012 and Bartha-K61.

    Science.gov (United States)

    Yu, Zhi-Qing; Tong, Wu; Zheng, Hao; Li, Li-Wei; Li, Guo-Xin; Gao, Fei; Wang, Tao; Liang, Chao; Ye, Chao; Wu, Ji-Qiang; Huang, Qinfeng; Tong, Guang-Zhi

    2017-09-01

    A newly emerged pseudorabies virus (PRV) variant has been identified in many Bartha-K61-vaccinated pig farms. This variant has caused great economic losses to the swine industry in China since 2011. Sequence analysis demonstrated that the gB gene of the emerging PRV variant JS-2012 had multiple variations compared with the vaccine strain Bartha-K61. In the study, a specific CRISPR/Cas9 system combined with homologous recombination was used to construct two recombinant viruses, BJB (Bartha-K61+JS-2012gB) and JBJ (JS-2012-ΔgE/gI+Bartha-K61gB), by interchanging the full-length gB genes between Bartha-K61 and JS-2012-ΔgE/gI. The two recombinant viruses showed similar characteristics in growth kinetics in vitro and similar pathogenicity in mice, as compared to their parental strains. Immunization of mice with inactivated BJB or JBJ followed by challenge of JS-2012 showed that BJB could increase protective efficacy to 80%, compared to only 40% protection by the parental Bartha-K61 strain. JBJ had a decreased protective efficacy of 65%, as compared to 90% protection by its parental JS-2012-ΔgE/gI strain. Exchange of the gB gene markedly altered the immunogenicity of the recombinant PRV. These data suggest that variations in gB might play an important role in the virulence of the reemergent PRV variant in China. Our results demonstrate the importance of gB in protective immunity and suggest that the recombinant virus BJB could be a promising vaccine candidate for eradication of the PRV variant. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. A live, attenuated pseudorabies virus strain JS-2012 deleted for gE/gI protects against both classical and emerging strains.

    Science.gov (United States)

    Tong, Wu; Li, Guoxin; Liang, Chao; Liu, Fei; Tian, Qing; Cao, Yanyun; Li, Lin; Zheng, Xuchen; Zheng, Hao; Tong, Guangzhi

    2016-06-01

    Emerging pseudorabies virus (PRV) variant have led to pseudorabies outbreaks in Chinese pig farms. The commercially available PRV vaccine provides poor protection against the PRV variant. In this study, a gE/gI deleted PRV strain JS-2012-△gE/gI was generated from a PRV variant strain using homologous DNA recombination. Compared to the parental strain JS-2012, JS-2012-△gE/gI grew slowly and showed small plaque morphology on Vero cells. The safety and immunological efficacy of JS-2012-△gE/gI was evaluated as a vaccine candidate. JS-2012-△gE/gI was avirulent to suckling piglets, but was able to provide full protection for young piglets against challenge with both the classical virulent PRV and the emerging PRV variant. After sows were vaccinated with the gE/gI-deleted strain, their suckling offspring were resistant to an otherwise lethal challenge with the classical and the variant PRVs. Piglets inoculated with JS-2012-△gE/gI did not develop PRV-specific gE-ELISA antibodies. Thus, JS-2012-△gE/gI appears to be a promising marker vaccine candidate to control PRV variant circulating in pig farms in China. Copyright © 2016 Elsevier B.V. All rights reserved.

  17. Automation of gamwave batch irradiator in Natal, South Africa

    International Nuclear Information System (INIS)

    Basson, J.K.; Basson, R.A.; Botha, J.

    1995-01-01

    High Energy Processing (HEPRO) has operated a Nordion JS 8200 Batch Irradiator for several years at Gamwave in Durban, South Africa. Product is loaded into aluminium totes and manually transported on trolleys into the irradiation chamber. Unirradiated totes are then exchanged with all the irradiated totes in the product pass mechanism, after which the source is raised and the batch irradiation process is started. Due to the inefficient Cobalt utilization experienced in this type of plant, it was decided to upgrade and automate the facility. This was done in what we believe is a simple and unique solution to the problem facing the future of such batch facilities. The design concept used for the Gamwave irradiator was based on irradiating product in carbons or bags of variable dimensions as per customer requirements. The intention was to convey product automatically in and out of the irradiation chamber eliminating the product change over downtime and thereby increasing source up utilization. Minor extensions were carried out to the Bioshield with the existing irradiator in full operation awaiting installation of the new source pass mechanism and conveyor system. Total plant shutdown for conversion to automation, including source reload and safety checks, was estimated to take ten days to fit the equipment. (author)

  18. Isolation and characterization of butachlor-catabolizing bacterial strain Stenotrophomonas acidaminiphila JS-1 from soil and assessment of its biodegradation potential.

    Science.gov (United States)

    Dwivedi, S; Singh, B R; Al-Khedhairy, A A; Alarifi, S; Musarrat, J

    2010-07-01

    Isolation, characterization and assessment of butachlor-degrading potential of bacterial strain JS-1 in soil. Butachlor-degrading bacteria were isolated using enrichment culture technique. The morphological, biochemical and genetic characteristics based on 16S rDNA sequence homology and phylogenetic analysis confirmed the isolate as Stenotrophomonas acidaminiphila strain JS-1. The strain JS-1 exhibited substantial growth in M9 mineral salt medium supplemented with 3.2 mmol l(-1) butachlor, as a sole source of carbon and energy. The HPLC analysis revealed almost complete disappearance of butachlor within 20 days in soil at a rate constant of 0.17 day(-1) and half-life (t((1/2))) of 4.0 days, following the first-order rate kinetics. The strain JS-1 in stationary phase of culture also produced 21.0 microg ml(-1) of growth hormone indole acetic acid (IAA) in the presence of 500 microg ml(-1) of tryptophan. The IAA production was stimulated at lower concentrations of butachlor, whereas higher concentrations above 0.8 mmol l(-1) were found inhibitory. The isolate JS-1 characterized as Stenotrophomonas acidaminiphila was capable of utilizing butachlor as sole source of carbon and energy. Besides being an efficient butachlor degrader, it substantially produces IAA. The bacterial strain JS-1 has a potential for butachlor remediation with a distinctive auxiliary attribute of plant growth stimulation.

  19. Instant Ember.js application development how-to

    CERN Document Server

    Bodmer, Marc

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. Get the job done and learn as you go. A how-To book with practical recipes accompanied with rich screenshots for easy comprehension.This book follows a recipe-based approach that can be used both for problem solving or getting started with Ember.JS. Regardless of your skill level you should find this book useful and beneficial to any of your application development projects.Are you a frontend developer whose code has gotten out of control? This book will also show you how you can us

  20. Analisis Sektor/Sub Sektor Unggulan di Kabupaten Bungo

    Directory of Open Access Journals (Sweden)

    Gafur Gafur

    2016-03-01

    Full Text Available Abstract. This study aimed to analyze the leading sectors in Bungo. The method used is Location Quotient (LQ, Dynamic Location Quotient (DLQ, specialization index, Growth Ratio Model (MRP. Based on analysis of LQ and DLQ, there are only two basis sectors at present and in the future, namely the construction sector and trade, hotels and restaurants. Based on the analysis of Specialization Index, in Bungo Regency has a concentration of the economy in the agricultural sector and the manufacturing sector. Based on MRP analysis also showed that prominent sector growth at the level of Bungo and Jambi Province, namely electricity, gas and water supply; the building sector; and trade, hotels and restaurants. Keywords : Location Quotient (LQ, Dinamic Location Quotient (DLQ, Specialization Index, Growth Ratio Model   Abstrak. Penelitian ini bertujuan untuk menganalisis sektor unggulan di Kabupaten Bungo. Metode yang digunakan adalah analisis Location Quotient (LQ, Dinamic Location Quotient (DLQ, indeks spesialisasi, Model Rasio Pertumbuhan (MRP. Berdasarkan analisis LQ dan DLQ,  hanya ada 2 sektor yang menjadi sektor basis pada saat ini dan pada masa yang akan datang yaitu sektor bangunan dan sektor perdagangan, hotel dan restoran. Berdasarkan analisis Indeks Spesialisasi, di Kabupaten Bungo telah terjadi konsentrasi ekonomi pada sektor pertanian dan sektor industri pengolahan. Berdasarkan analisis MRP juga dapat diketahui bahwa sektor yang menonjol pertumbuhannya pada tingkat Kabupaten Bungo dan Provinsi Jambi yaitu sektor listrik, gas dan air bersih; sektor bangunan; serta sektor perdagangan, hotel dan restoran. Kata Kunci : Location Quotient (LQ, Dinamic Location Quotient (DLQ, indeks spesialisasi, Model Rasio Pertumbuhan

  1. Analisis dan Desain BI-Dashboard Monitoring Realisasi Daftar Isian Pelaksanaan Anggaran (DIPA pada Kantor Pelayanan Perbendaharaan Negara (KPPN

    Directory of Open Access Journals (Sweden)

    Ernestina Rahmanasari

    2013-09-01

    Full Text Available Transaksi keuangan badan pemerintahan tingkat daerah dipertanggungjawabkan kepada Kementrian Keuangan melalui Kantor Pelayanan Perbendaharaan Negara (KPPNsetiap bulan dalam bentuk Laporan Keuangan Pemerintah Pusat (LKPP. Laporan Keuangan, didukung dengan teknologi Business Intelligence(BI dashboarddapat dimanfaatkan sebagai data-driven decision support system yang mendorong performa kinerja. Analisis dan desainterhadap pembuatan BI dashboard menunjukkanbagaimana Laporan Keuangan dapat digunakan untuk monitoring realisasi penyerapan dana DIPA dan kinerja instansi secara tepat waktu dan interaktif.Analisis terdiri dari analisis Indikator Kinerja Utama (IKU dan analisis Laporan Keuangan. IKUpada analisis dan desain ini mencakup ketercapaian estimasi dengan penerimaan, ketercapaian pagu dengan belanja, ketepatan waktu pengiriman rekonsiliasi oleh instansi, validasi, akurasi, dan ketepatan data. Desain terdiri dari katalog dashboard, alur analisis, sumber data, desain User-Interface, dan desain objek dashboard. Sedangkan dashboard yang dirancang menggunakan aplikasi Vera sebagai Enterprise System, mengakses basis data MySQL, dan menampilkan data dengan teknologi data-driven business-intelligence Qlikview. Desain aplikasi yang telah dibuat akan menampilkan 4 (empat Tab yaitu: Dashboard utama, Analisis, Monitoring, dan Laporan

  2. Protein phosphatase 2A mediates JS-K-induced apoptosis by affecting Bcl-2 family proteins in human hepatocellular carcinoma HepG2 cells.

    Science.gov (United States)

    Liu, Ling; Huang, Zile; Chen, Jingjing; Wang, Jiangang; Wang, Shuying

    2018-04-25

    Protein phosphatase 2A (PP2A) is an important enzyme within various signal transduction pathways. The present study was investigated PP2A mediates JS-K-induced apoptosis by affecting Bcl-2 family protein. JS-K showed diverse inhibitory effects in five HCC cell lines, especially HepG2 cells. JS-K caused a dose- and time-dependent reduction in cell viability and increased in levels of LDH release. Meanwhile, JS-K- induced apoptosis was characterized by mitochondrial membrane potential reduction, Hoechst 33342 + /PI + dual staining, release of cytochrome c (Cyt c), and activation of cleaved caspase-9/3. Moreover, JS-K-treatment could lead to the activation of protein phosphatase 2A-C (PP2A-C), decrease of anti-apoptotic Bcl-2 family-protein expression including p-Bcl-2 (Ser70), Bcl-2, Bcl-xL, and Mcl-1 as well as the increase of pro-apoptosis Bcl-2 family-protein including Bim, Bad, Bax, and Bak. Furthermore, JS-K caused a marked increase of intracellular NO levels while pre-treatment with Carboxy-PTIO (a NO scavenger) reduced the cytotoxicity effects and the apoptosis rate. Meanwhile, pre-treatment with Carboxy-PTIO attenuated the JS-K-induced up-regulation of PP2A, Cyt c, and cleaved-caspase-9/3 activation. The silencing PP2A-C by siRNA could abolish the activation of PP2A-C, down-regulation of anti-apoptotic Bcl-2 family-protein (p-Bcl-2, Bcl-2, Bcl-xL, and Mcl-1), increase of pro-apoptosis Bcl-2 family-protein (Bim, Bad, Bax, and Bak) and apoptotic-related protein (Cyt c, cleaved caspase-9/3) that were caused by JS-K in HepG2 cells. In addition, pre-treatment with OA (a PP2A inhibitor) also attenuated the above effects induced by JS-K. In summary, NO release from JS-K induces apoptosis through PP2A activation, which contributed to the regulation of Bcl-2 family proteins. © 2018 Wiley Periodicals, Inc.

  3. Semiotika Teks: Sebuah Pendekatan Analisis Teks

    Directory of Open Access Journals (Sweden)

    Yasraf Amir Piliang

    2004-12-01

    tanda-tanda yang membentuk apa yang disebut sebagai ‘teks’. Analisis teks, menurut Roland Barthes, akan menghasilkan makna denotatif, yakni makna tanda yang bersifat eksplisit, dan makna konotatif, yaitu makna tanda lapis kedua yang bersifat implisit.

  4. Microfinanza: analisi d’impatto di un programma in India

    Directory of Open Access Journals (Sweden)

    Tommaso Rondinella

    2005-03-01

    Full Text Available L’analisi d’impatto dei programmi di microfinanza è uno strumento utile sia per migliorare i servizi offerti sia per garantire ai donatori che il denaro concesso sia utilizzato per programmi efficaci nell’alleviare la povertà. Il presente lavoro è costituito da due parti: la prima è dedicata all’analisi d’impatto, la seconda all’analisi empirica sul campo. L’indagine è stata condotta attraverso l’utilizzo di uno strumento in grado di dare una indicazione chiara dei cambiamenti avvenuti nelle condizioni di vita dei beneficiari e con il pregio di essere applicabile a costi molto ridotti. I risultati ottenuti mostrano in che misura l’accesso al credito cambi le condizioni di vita dei più poveri inducendo consistenti aumenti del reddito familiare, dei risparmi, della diversificazione delle attività produttive e del consumo di cibo. Inoltre si osserva, all’interno dei nuclei familiari, un miglioramento della condizione femminile chiaramente dipendente dalla partecipazione al programma di microcredito

  5. Analysis of the Volatile Constituents of Irradiated Apple Juice; Analyse des Constituants Volatils des Jus de Pommes Irradies; Mezhdunarodnyj proekt po oblucheniyu fruktov i fruktovykh sokov; Analisis de los Componentes Volatiles de los Zumos de Manzana Irradiados

    Energy Technology Data Exchange (ETDEWEB)

    Dubois, P.; Zenz, H.; Stehlik, G.; Kaindl, K. [Agence Europeenne pour l' Energie Nucleaire, Seibersdorf (Austria)

    1966-11-15

    Degree-Sign C (Head Space Technique de Weurman). Les identifications ont ete faites par comparaison des volumes de retention avec ceux de substances pures, et a l'aide de reactifs chimiques permettant d'eliminer certains constituants de la vapeur. Pour simplifier les analyses, les premiers essais ont porte sur des concentres de jus de pommes ne contenant plus de substances volatiles avant irradiation. Par irradiation, cinq aldehydes prennent naissance dans les jus de pommes: acetaldehyde, isobutyraldehyde, butyraldehyde, isovaleraldehyde et capronaldehyde; mais trois seulement dans les jus concentres; acetaldehyde, isobutyraldehyde et isovaleraldehyde. De plus, la 2-butanone apparait dans les jus concentres, mais le pic qui lui correspond sur les chroma- togrammes est entierement masque par celui de l'ethanol dans le cas des jus non concentres. Par ailleurs on a mis en evidence les formations de furane et de deux composes qui n'apparaissent qu'a l'etat de traces et qui n'ont pas pu etre identifies a ce jour. Des resultats analogues ont ete obtenus par pasteurisation, telle qu'elle est realisee par embouteillage a chaud. (author) [Spanish] Los estudios organolepticos y los ensayos de inocuidad que se realizan dentro del marco del proyecto internacional de investigaciones sobre la conservacion de frutas y zumos de fruta por irradiacion (Seibersdorf) hacen indispensable el analisis de las sustancias aromaticas de los zumos irradiados y no irradiados. Las sustancias volatiles de los zumos de manzana irradiados han sido analizados por cromatografia en fase gaseosa, inyectando directamente los vapores que emiten a la temperatura ambiente y a 60 Degree-Sign C (tecnica 'Head Space' , de Weurman). Las identificaciones se han efectuado comparando los volumenes de retencion con los de sustancias puras y eliminando ciertos constituyentes del vapor con reactivos quimicos. Para simplificar los analisis, los primeros ensayos se han efectuado con concentrados de zumos de manzana que no

  6. Molecular characterization of two sweepoviruses from China and evaluation of the infectivity of cloned SPLCV-JS in Nicotiana benthamiana.

    Science.gov (United States)

    Bi, Huiping; Zhang, Peng

    2012-03-01

    Sweepoviruses are important begomoviruses that infect Ipomoea plants worldwide and cause sweet potato yield losses and cultivar decline. Two sweepoviruses, sweet potato leaf curl virus-Jiangsu (SPLCV-JS) and sweet potato leaf curl China virus-Zhejiang (SPLCCNV-ZJ), were cloned from diseased sweet potato plants collected in the Jiangsu and Zhejiang provinces of China. Sequence characterization and phylogenetic analysis demonstrated that both are typical monopartite begomoviruses and have close relationships to several reported SPLCV and SPLCCNV isolates, respectively, from Asian countries. Analysis of the protein alignments and subcellular localizations of the six SPLCV-JS proteins was also conducted to verify their putative functions. In Nicotiana benthamiana, an infectivity assay of the infectious SPLCV-JS clone resulted in mild symptoms and weak viral DNA accumulation. Interestingly, SPLCV-JS, together with a heterologous betasatellite DNA (tomato yellow leaf curl China virus isolate Y10 [TYLCCNV-Y10] DNA-β), showed a synergistic effect on enhanced symptom severity and viral DNA accumulation. This is the first reported infectious SPLCV clone.

  7. ANALISIS KINERJA KEUANGAN PERUSAHAAN PT. ASURANSI JIWASRAYA (PERSERO) CABANG SULAWESI SELATAN

    OpenAIRE

    ARIANTY, ASTRI

    2012-01-01

    ANALISIS KINERJA KEUANGAN PERUSAHAAN PT. ASURANSI JIWASRAYA (PERSERO) CABANG SULAWESI SELATAN COMPANY FINANCIAL PERFORMANCE ANALYSIS PT. INSURANCE JIWASRAYA (LIMITED) SOUTH BRANCH SULAWESI Astri Arianty Prof. Dr. H. Muhammad Ali, SE., M.S Drs. Armayah Sida, M.Si Analisis terhadap kinerja keuangan perusahaan sangat penting dilakukan untuk mengetahui sejauh mana tingkat pencapaian yang telah diperoleh perusahaan sebagaimana tujuan perusahaan dalam menjalankan proses produk...

  8. JS-K, a GST-activated nitric oxide donor prodrug, enhances chemo-sensitivity in renal carcinoma cells and prevents cardiac myocytes toxicity induced by Doxorubicin.

    Science.gov (United States)

    Qiu, Mingning; Ke, Longzhi; Zhang, Sai; Zeng, Xin; Fang, Zesong; Liu, Jianjun

    2017-08-01

    Doxorubicin, a highly effective and widely used anthracycline antibiotic in multiple chemotherapy regimens, has been limited by its cardiotoxicity. The aim of this study is to investigate the effect of nitric oxide donor prodrug JS-K on proliferation and apoptosis in renal carcinoma cells and cardiac myocytes toxicity induced by Doxorubicin and to explore possible p53-related mechanism in renal carcinoma cells. The effect of JS-K on anti-cancer activity of Doxorubicin was investigated in renal carcinoma cells via detecting cell proliferation, cytotoxicity, cell death and apoptosis and expressions of apoptotic-related proteins. Effect of p53 on the combination of JS-K and Doxorubicin was determined using p53 inhibitor Pifithrin-α and p53 activator III. Furthermore, the effect of JS-K on cardiac myocytes toxicity of Doxorubicin was investigated in H9c2 (2-1) cardiac myocytes via measuring cell growth, cell death and apoptosis, expressions of proteins involved in apoptosis and intracellular reactive oxygen species. We demonstrated that JS-K could increase Doxorubicin-induced renal carcinoma cell growth suppression and apoptosis and could increase expressions of proteins that are involved in apoptosis. Additionally, Pifithrin-α reversed the promoting effect of JS-K on Doxorubicin-induced renal carcinoma cell apoptosis; conversely, the p53 activator III exacerbated the promoting effect of JS-K on Doxorubicin-induced renal carcinoma cell apoptosis. Furthermore, JS-K protected H9c2 (2-1) cardiac myocytes against Doxorubicin-induced toxicity and decreased Doxorubicin-induced reactive oxygen species production. JS-K enhances the anti-cancer activity of Doxorubicin in renal carcinoma cells by upregulating p53 expression and prevents cardiac myocytes toxicity of Doxorubicin by decreasing oxidative stress.

  9. BioJS DAGViewer: A reusable JavaScript component for displaying directed graphs.

    Science.gov (United States)

    Kalderimis, Alexis; Stepan, Radek; Sullivan, Julie; Lyne, Rachel; Lyne, Michael; Micklem, Gos

    2014-01-01

    The DAGViewer BioJS component is a reusable JavaScript component made available as part of the BioJS project and intended to be used to display graphs of structured data, with a particular emphasis on Directed Acyclic Graphs (DAGs). It enables users to embed representations of graphs of data, such as ontologies or phylogenetic trees, in hyper-text documents (HTML). This component is generic, since it is capable (given the appropriate configuration) of displaying any kind of data that is organised as a graph. The features of this component which are useful for examining and filtering large and complex graphs are described. http://github.com/alexkalderimis/dag-viewer-biojs; http://github.com/biojs/biojs; http://dx.doi.org/10.5281/zenodo.8303.

  10. Perumusan Strategi Bersaing pada Perusahaan Ban dengan Metode Analisis Portofolio Produk (Studi Kasus: PT Multistrada Arah Sarana, Tbk

    Directory of Open Access Journals (Sweden)

    Nathanael August Zefanya

    2017-01-01

    Full Text Available Industri ban di Indonesia mengalami perkembangan pesat dalam kurun waktu 10 tahun terakhir. Namun, terjadinya krisis ekonomi global menjadi penyebab menurunnya pendapatan, salah satunya adalah PT MASA dengan produk utamanya yaitu ban mobil Achilles dan ban motor Corsa yang digunakan sebagai objek penelitian ini. Telah diilakukan analisis PESTEL dan Porter’s Five Forces, identifikasi faktor lingkungan internal dan eksternal dengan analisis SWOT serta merumuskan alternatif strategi bersaing untuk direkomendasikan kepada PT MASA. Perumusan strategi alternatif didapat dari hasil analisis Matriks BCG dan Matriks IE sebagai analisis portofolio untuk mendapatkan tema strategi alternatif dalam pembuatan Matriks SWOT. Strategi alternatif kemudian diperingkatkan dengan QSPM dan dilanjutkan pembuatan rencana aksi bagi PT MASA dalam waktu 5 tahun ke depan. Setelah dilakukan analisis industri, diketahui bahwa ancaman terbesar datang dari pesaing produsen ban. Dari hasil analisis portofolio, PT MASA berada di kuadran I karena memiliki koordinat IFE serta EFE 3,32 dan 3,26. Dari hasil analisis Matriks IE, PT MASA direkomendasikan untuk melakukan strategi grow and build. Hasil Matriks BCG menunjukkan bahwa Achilles berada di dogs, sementara Corsa berada di question marks. Terdapat 13 strategi alternatif hasil dari formulasi strategi dengan menggunakan matriks TOWS. Dari hasil analisis QSPM, terdapat 7 alternatif strategi terbaik dan rencana aksi..

  11. Participation of SKODA JS in the construction of the Temelin and Mochovce nuclear power plants

    International Nuclear Information System (INIS)

    Svec, A.; Zach, J.; Ruzicka, P.

    2000-01-01

    SKODA JS is the traditional manufacturer of WWER type reactor equipment and also supplier of the primary circuits and of equipment for the transport, refuelling and storage of fuel for Ver type nuclear power plants built in the Czech and Slovak Republics. The paper deals with activities of the company SKODA JS at two power plants whose reactor units are close to completion, viz. the Mochovce NPP in the Slovak Republic (4 x Ver 440 MW; unit 1 was put in operation in 1998, unit 2 is in the stage of commissioning, units 3 and 4 are not to be completed) and the Temelin NPP in the Czech Republic (2 x Ver 1000 MW, commissioning of units 1 and 2 is expected in 2001 and 2002, respectively). The scope of supplies to the two nuclear power plants (detailed design, delivery of equipment, installation, commissioning) and the course of construction from SKODA JS's viewpoint are described. The most important design changes and improvements made during the construction are highlighted. (author)

  12. ANALISIS ATRIBUT-ATRIBUT YANG MEMPENGARUHI TINGKAT KEPUASAN PELANGGAN TELEPON RUMAH (FIXED WIRELINE MENGGUNAKAN METODE ANALISIS DISKRIMINAN (STUDI KASUS DI PT. TELKOM KANDATEL SEMARANG

    Directory of Open Access Journals (Sweden)

    Diana Puspita Sari

    2012-02-01

    Full Text Available PT Telkom memiliki misi untuk memberikan layanan One Stop Infocom dengan kualitas prima dan harga kompetitif. Kenyataannya, PT. Telkom Kandatel Semarang mengalami penurunan pendapatan. Semakin berkembangnya layanan jasa fixed wireless yang lebih mudah dan murah, menyebabkan penurunan pemakaian jasa fixed wireline. Dengan konsumen melakukan pembelian pertama pada suatu produk tertentu dengan harga terjangkau, kualitas terjamin, maka konsumen akan kembali membeli produk tersebut, dan dampaknya dari fenomena ini adalah kepuasan pelanggan (customer satisfaction terhadap produk tertentu karena telah memberikan kepuasan dan terjaminnya kualitas, walaupun banyak pesaing lain.  Oleh sebab itu, penelitian ini membahas dan melakukan analisis kepuasan pelanggan fixed wireline PT. Telkom Kandatel Semarang, menggunakan variabel kepuasan pelanggan untuk dikelompokkan menjadi tiga tingkatan yaitu pelanggan yang sangat puas, puas, dan tidak puas dengan menggunakan analisis klaster, kemudian dilakukan analisis variabel 4P Customer Relationship Management (CRM menggunakan analisis diskriminan, sehingga diketahui atribut yang mempengaruhi tingkat kepuasan pelanggan agar PT. Telkom Kandatel Semarang dapat terus mempertahankan dan meningkatkan kepuasan pelanggan dengan berusaha memenuhi kebutuhan dan keinginan pelanggan dengan maksud kepuasan pelanggan tidak menurun agar dapat meningkatkan intensitas pemakaian fixed wireline. Kata kunci : analisis klaster, analisis diskriminan, kepuasan pelanggan, fixed wireline      PT Telkom has a mission to provide a One Stop Infocom services with excellent quality and competitive price. In fact, PT. Telkom Semarang Kandatel income decreased. The growing fixed wireless service is easier and cheaper, causes a decrease in the use of fixed wireline services.With the first consumer purchase a given product at an affordable price, guaranteed quality, then consumers will buy the product again, and the impact of this phenomenon is

  13. From flipchart to glossy visualisation through collaboration and d3.js

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    Representing complex data visually is an important tool for communication, and the CERN Knowledge Transfer Annual Report is no exception to this. I want to share with the audience our experience with data visualization through the strength of collaboration, and the power and simplicity of the d3.js javascript framework.

  14. Preclinical evaluation of the efficacy, pharmacokinetics and immunogenicity of JS-001, a programmed cell death protein-1 (PD-1) monoclonal antibody.

    Science.gov (United States)

    Fu, Jie; Wang, Fang; Dong, Li-Hou; Zhang, Jing; Deng, Cheng-Lian; Wang, Xue-Li; Xie, Xin-Yao; Zhang, Jing; Deng, Ruo-Xian; Zhang, Li-Bo; Wu, Hai; Feng, Hui; Chen, Bo; Song, Hai-Feng

    2017-05-01

    JS-001 is the first monoclonal antibody (mAb) against programmed cell death protein-1 (PD-1) approved by the China Food and Drug Administration (CFDA) into the clinical trails. To date, however, no pre-clinical pharmacological and pharmacokinetic (PK) data are available. In this study, we investigated the efficacy of JS-001 and conducted a preclinical PK study, including the monitoring of anti-drug antibodies (ADAs). We found that JS-001 specifically bound to PD-1 antigen with an EC 50 of 21 nmol/L, and competently blocked the binding of PD-1 antigen to PD-L1 and PD-L2 with IC 50 of 3.0 and 3.1 nmol/L, respectively. Furthermore, JS-001 displayed distinct species cross-reactivity: it could bind to the PD-1 antigen on the peripheral blood mononuclear cells (PBMCs) of humans and cynomolgus monkeys, but not to those of mice and woodchucks; the K d values for the interaction between JS-001 and PD-1 antigens on CD8 + T cells of human and cynomolgus monkey were 2.1 nmol/L and 1.2 nmol/L, respectively. In vitro, treatment with JS-001 (0.01-10 μg/mL) dose-dependently stimulated human T cell proliferation, as well as IFN-γ and TNF-α secretion. In HBsAg-vaccinated cynomolgus monkeys, the expression of PD-1 + /CD4 + and PD-1 + /CD8 + was significantly elevated, intramuscular injection of JS-001 (1 and 10 mg/kg) resulted in dramatic decreases in PD-1 + /CD4 + and PD-1 + /CD8 + expression in a dose-dependent manner, which was supported by PD-1 receptor occupancy (RO) results. In the PK study, 18 cynomolgus monkeys treated with single, ascending doses of 1, 10, and 75 mg/kg, and another 6 cynomolgus monkeys received 10 mg/kg successive administration. The plasma clearance of JS-001 followed a linear PK profile with single administration in the 1 and 10 mg/kg groups and a non-linear PK profile in the 75 mg/kg group. In the successive 10 mg/kg administration group, no drug accumulation was observed. But the AUC from the last exposure was lower than that of the first

  15. JS-K, a glutathione/glutathione S-transferase-activated nitric oxide releasing prodrug inhibits androgen receptor and WNT-signaling in prostate cancer cells.

    Science.gov (United States)

    Laschak, Martin; Spindler, Klaus-Dieter; Schrader, Andres J; Hessenauer, Andrea; Streicher, Wolfgang; Schrader, Mark; Cronauer, Marcus V

    2012-03-30

    Nitric oxide (NO) and its oxidative reaction products have been repeatedly shown to block steroid receptor function via nitrosation of zinc finger structures in the DNA-binding domain (DBD). In consequence NO-donors could be of special interest for the treatment of deregulated androgen receptor(AR)-signaling in castration resistant prostate cancer (CRPC). Prostate cancer (PCa) cells were treated with JS-K, a diazeniumdiolate derivate capable of generating large amounts of intracellular NO following activation by glutathione S-transferase. Generation of NO was determined indirectly by the detection of nitrate in tissue culture medium or by immunodetection of nitrotyrosine in the cytoplasm. Effects of JS-K on intracellular AR-levels were determined by western blotting. AR-dimerization was analyzed by mammalian two hybrid assay, nuclear translocation of the AR was visualized in PCa cells transfected with a green fluorescent AR-Eos fusion protein using fluorescence microscopy. Modulation of AR- and WNT-signalling by JS-K was investigated using reporter gene assays. Tumor cell proliferation following JS-K treatment was measured by MTT-Assay. The NO-releasing compound JS-K was shown to inhibit AR-mediated reporter gene activity in 22Rv1 CRPC cells. Inhibition of AR signaling was neither due to an inhibition of nuclear import nor to a reduction in AR-dimerization. In contrast to previously tested NO-donors, JS-K was able to reduce the intracellular concentration of functional AR. This could be attributed to the generation of extremely high intracellular levels of the free radical NO as demonstrated indirectly by high levels of nitrotyrosine in JS-K treated cells. Moreover, JS-K diminished WNT-signaling in AR-positive 22Rv1 cells. In line with these observations, castration resistant 22Rv1 cells were found to be more susceptible to the growth inhibitory effects of JS-K than the androgen dependent LNCaP which do not exhibit an active WNT-signaling pathway. Our results

  16. Pembuatan Dan Analisis Exciter Generator Rf Untuk Siklotron Proton Decy-13

    OpenAIRE

    Prajitno, Prajitno

    2011-01-01

    PEMBUATAN DAN ANALISIS EXCITER GENERATOR RF UNTUK SIKLOTRON PROTON DECY-13.Telah dilakukan analisis dan pembuatan exciter generator RF untuk siklotron proton 13MeV. Generator RFakan digunakan sebagai sumber tegangan pemercepat bolak-Balik siklotron DECY-13 rancangan PTAPBBATAN.Berdasarkan dokumen rancangan dasar yang telah dibuat siklotron Decy-13 akan menggunakanmedan magnet 1,275 Tesla, sehingga frekuensi generator RF bila menggunakan harmonik keempat adalah77,667 MHz. Salah satu teknik pem...

  17. Analisis Aliran Daya Berbasis Injeksi Arus dalam Bentuk Vektor

    Directory of Open Access Journals (Sweden)

    Ahmad Wira Satriawan

    2017-11-01

    Full Text Available Tulisan ini memaparkan hasil penelitian yang telah dilakukan untuk membandingkan metode analisis aliran daya berbasis injeksi arus dalam bentuk vektor dengan format polar dan rektangular. Penelitian ini dilakukan untuk memperoleh metode analisa aliran daya dengan perhitungan yang lebih cepat dan akurat, serta iterasi yang lebih sedikit. Metode iterasi Newton Raphson diadopsi dalam penelitian ini dan bahasa pemrograman Python serta library komputasinya digunakan. Analisis terhadap karakteristik konvergensi dari kedua format dilakukan pada IEEE 14-bus Test System. Dari penelitian ini diperoleh hasil bahwa format rektangular lebih unggul dibandingkan format polar untuk kasus yang diteliti.

  18. JS-K, a nitric oxide prodrug, induces DNA damage and apoptosis in HBV-positive hepatocellular carcinoma HepG2.2.15 cell.

    Science.gov (United States)

    Liu, Zhengyun; Li, Guangmin; Gou, Ying; Xiao, Dongyan; Luo, Guo; Saavedra, Joseph E; Liu, Jie; Wang, Huan

    2017-08-01

    Hepatocellular carcinoma (HCC) is the most important cause of cancer-related death, and 85% of HCC is caused by chronic HBV infection, the prognosis of patients and the reduction of HBV DNA levels remain unsatisfactory. JS-K, a nitric oxide-releasing diazeniumdiolates, is effective against various tumors, but little is known on its effects on HBV positive HCC. We found that JS-K reduced the expression of HBsAg and HBeAg in HBV-positive HepG2.2.15 cells. This study aimed to further examine anti-tumor effects of JS-K on HepG2.2.15 cells. The MTT assay and colony forming assay were used to study the cell growth inhibition of JS-K; scratch assay and transwell assay were performed to detect cell migration. The cell cycle was detected by flow cytometry. The immunofluorescence, flow cytometry analysis, and western blot were used to study DNA damage and cell apoptosis. JS-K inhibited HepG2.2.15 cell growth in a dose-dependent manner, suppressed cell colony formation and migration, arrested cells gather in the G2 phase. JS-K (1-20μM) increased the expression of DNA damage-associated protein phosphorylation H 2 AX (γH 2 AX), phosphorylation of checkpoint kinase 1 (p-Chk1), phosphorylation of checkpoint kinase 2 (p-Chk2), ataxia-telangiectasia mutated (ATM), phosphorylation of ataxia-telangiectasia mutated rad3-related (p-ATR) and apoptotic-associated proteins cleaved caspase-3, cleaved caspase-7, cleaved poly ADP-ribose polymerase (cleaved PARP). The study demonstrated JS-K is effective against HBV-positive HepG2.2.15 cells, the mechanisms are not only related to inhibition of HBsAg and HBeAg secretion, but also related with induction of DNA damage and apoptosis. JS-K is a promising anti-cancer candidate against HBV-positive HCC. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  19. JS-K, a nitric oxide-releasing prodrug, modulates ß-catenin/TCF signaling in leukemic Jurkat cells: evidence of an S-nitrosylated mechanism.

    Science.gov (United States)

    Nath, Niharika; Chattopadhyay, Mitali; Pospishil, Liliya; Cieciura, Lucyna Z; Goswami, Satindra; Kodela, Ravinder; Saavedra, Joseph E; Keefer, Larry K; Kashfi, Khosrow

    2010-12-01

    β-Catenin is a central player of the Wnt signaling pathway that regulates cell-cell adhesion and may promote leukemia cell proliferation. We examined whether JS-K, an NO-donating prodrug, modulates the Wnt/β-catenin/TCF-4 signaling pathway in Jurkat T-Acute Lymphoblastic Leukemia cells. JS-K inhibited Jurkat T cell growth in a concentration and time-dependent manner. The IC(50)s for cell growth inhibition were 14±0.7 and 9±1.2μM at 24 and 48h, respectively. Treatment of the cells with JS-K for 24h, caused a dose-dependent increase in apoptosis from 16±3.3% at 10μM to 74.8±2% at 100μM and a decrease in proliferation. This growth inhibition was also due, in part, to alterations in the different phases of the cell cycle. JS-K exhibited a dose-dependent cytotoxicity as measured by LDH release at 24h. However, between 2 and 8h, LDH release was less than 20% for any indicated JS-K concentration. The β-catenin/TCF-4 transcriptional inhibitory activity was reduced by 32±8, 63±5, and 93±2% at 2, 10, and 25μM JS-K, respectively, based on luciferase reporter assays. JS-K reduced nuclear β-catenin and cyclin D1 protein levels, but cytosolic β-catenin expression did not change. Based on a time-course assay of S-nitrosylation of proteins by a biotin switch assay, S-nitrsolyation of nuclear β-catenin was determined to precede its degradation. A comparison of the S-nitrosylated nuclear β-catenin to the total nuclear β-catenin showed that β-catenin protein levels were degraded at 24h, while S-nitrosylation of β-catenin occurred earlier at 0-6h. The NO scavenger PTIO abrogated the JS-K mediated degradation of β-catenin demonstrating the need for NO. Copyright © 2010 Elsevier Inc. All rights reserved.

  20. Shore displacement in northern Uppland during the last 6500 calender years

    Energy Technology Data Exchange (ETDEWEB)

    Hedenstroem, Anna; Risberg, Jan [Stockholm Univ. (Sweden). Dept. of Physical Geography and Quaternary Geology

    2003-10-01

    This report describes the shore displacement in northern Uppland, Sweden. Four lake basins were investigated regarding elevation and age of their isolation events. The methods applied were diatom stratigraphy and AMS radiocarbon datings of terrestrial macrofossils, together with analysis of water, organic carbon and calcium carbonate in the sediment. Lake Barsjoe (22.5 masl -meters above sea level) was isolated 3,200 cal yrs BP, Lake Landholmssjoen (16.0 masl) 2,200 cal yrs BP, Lake Soedra Aassjoen (10.8 masl) 1,400 cal yrs BP and Lake Eckarfjaerden (5.5 masl) 850 cal yrs BP. Combined with six basins located at approximately the 70 m Litorina Limit isobase it was concluded that the shore displacement during the last 6500 calendar years was regressive in nature. The isolation processes, however, seem to have been prolonged at 4750-4150 cal yrs BP, 2500-2200 cal yrs Bp and 1100-850 cal yrs BP. These events can be correlated with eustatic sea level rises recorded in the Stockholm area. The diatom succession during the formation of the oligotrophic hardwater Lakes Barsjoe, Landholmssjoen and Eckarfjaerden differs from the brownwater Lake Soedra Aasjoen. Short pre-isolation sequences indicate that erosion has affected the four basins investigated. Accumulation rates in the lake basins vary between 0.5 mm/year in Lake Barsjoe and 1.5 mm/year in Lake Soedra Aasjoen.

  1. Shore displacement in northern Uppland during the last 6500 calender years

    International Nuclear Information System (INIS)

    Hedenstroem, Anna; Risberg, Jan

    2003-10-01

    This report describes the shore displacement in northern Uppland, Sweden. Four lake basins were investigated regarding elevation and age of their isolation events. The methods applied were diatom stratigraphy and AMS radiocarbon datings of terrestrial macrofossils, together with analysis of water, organic carbon and calcium carbonate in the sediment. Lake Barsjoe (22.5 masl -meters above sea level) was isolated 3,200 cal yrs BP, Lake Landholmssjoen (16.0 masl) 2,200 cal yrs BP, Lake Soedra Aassjoen (10.8 masl) 1,400 cal yrs BP and Lake Eckarfjaerden (5.5 masl) 850 cal yrs BP. Combined with six basins located at approximately the 70 m Litorina Limit isobase it was concluded that the shore displacement during the last 6500 calendar years was regressive in nature. The isolation processes, however, seem to have been prolonged at 4750-4150 cal yrs BP, 2500-2200 cal yrs Bp and 1100-850 cal yrs BP. These events can be correlated with eustatic sea level rises recorded in the Stockholm area. The diatom succession during the formation of the oligotrophic hardwater Lakes Barsjoe, Landholmssjoen and Eckarfjaerden differs from the brownwater Lake Soedra Aasjoen. Short pre-isolation sequences indicate that erosion has affected the four basins investigated. Accumulation rates in the lake basins vary between 0.5 mm/year in Lake Barsjoe and 1.5 mm/year in Lake Soedra Aasjoen

  2. ANALISIS CLUSTER K-MEANS DALAM PENGELOMPOKAN KEMAMPUAN MAHASISWA

    Directory of Open Access Journals (Sweden)

    B. Poerwanto

    2016-12-01

    Full Text Available Abstract. Cluster Analysis, K-Means Algorithm, Student Classification. This study aims to classify students based on learning outcomes for subject the basic of statistics (DDS, which is measured based on attendance, task, midterm (UTS, and final exams (UAS to further used to evaluate learning for subjects that require analysis of quantitative . This study uses k-means cluster analysis to classify the students into three groups based on learning outcomes. After grouped, there are 3 people in the low category, 27 in the medium category and over 70% in the high category.Abstrak. Analisis Cluster K-Means dalam Pengelompokan Kemampuan Mahasiswa. Pene-litian ini bertujuan untuk mengelompokkan mahasiswa berdasarkan hasil belajar mata kuliah dasar-dasar statistika (DDS yang diukur berdasarkan variabel nilai kehadiran, tugas, ujian tengah semester (UTS, dan ujian akhir semester (UAS untuk selanjutnya digunakan untuk mengevaluasi pembelajaran untuk mata kuliah yang membutuhkan kemampuan analisis kuantititatif yang baik. Penelitian ini menggunakan analisis cluster k-means dalam mengelompokkan mahasiswa ke dalam tiga kelompok berdasarkan hasil belajarnya. Seteleh dikelompokkan, terdapat 3 orang yang masuk pada kategori rendah, 27 orang pada kategori sedang dan lebih dari 70% pada kategori tinggi.Kata Kunci: Cluster Analysis, K-Means Algoritma, Klasifikasi Mahasiswa, Universitas Cokroaminoto Palopo

  3. Klasifikasi Kecamatan Berdasarkan Nilai Akhir SMA/MA di Kabupaten Aceh Selatan Menggunakan Analisis Diskriminan

    Directory of Open Access Journals (Sweden)

    Fitriana A.R.

    2015-11-01

    Full Text Available Analisis diskriminan merupakan bagian dari analisis peubah ganda. Analisis diskriminan digunakan untuk memodelkan variabel tak bebas yang bersifat kualitatif dengan variabel bebas yang bersifat kuantitatif. Pada penelitian ini, analisis diskriminan lebih dari dua kelompok diterapkan pada data nilai akhir SMA/MA di Kabupaten Aceh Selatan yang bertujuan untuk mendapatkan model untuk pengklasifikasian kecamatan. Pengklasifikasian ini bertujuan untuk melihat perbedaan kualitas siswa SMA/MA yang berada di masing-masing kecamatan Kabupaten Aceh Selatan berdasarkan data nilai akhir. Variabel tak bebas yang digunakan berupa klasifikasi kecamatan berdasarkan rata-rata jumlah nilai akhir SMA/MA yang berada di masing-masing kecamatan yang dibentuk dengan K-Means Cluster. Sedangkan variabel bebas yang digunakan adalah data rata-rata nilai akhir SMA/MA untuk setiap mata pelajaran yang diujiankan pada masing-masing jurusan setiap kecamatan. Model yang didapatkan adalah dua model diskriminan untuk jurusan IPA dan IPS.

  4. SKODA JS in Central and Eastern European markets

    International Nuclear Information System (INIS)

    Luptacik, P.

    2006-01-01

    During the past decade, SKODA JS a.s. gained a leading position in the manufacture of equipment for the nuclear power sector in Central and Eastern Europe. The company benefited from its experience accumulated during the construction of VVER 440 and VVER 1000 NPPs at a time that saw a global decrease in popularity of the nuclear power sector. The company is building its success on a comprehensive understanding of the function of the primary coolant circuit and efforts to upgrade the equipment and processes so as to reflect new requirements in terms of safety and reactor unit service life. (orig.)

  5. PENGUKURAN KINERJA PERUSAHAAN PT. HADJI KALLA DENGAN MENGGUNAKAN ANALISIS ECONOMIC VALUE ADDED

    OpenAIRE

    2013-01-01

    Tujuan dari penelitian ini adalah mengetahui kinerja Economic Value Added (EVA) yang dicapai oleh perusahaan PT. Hadji Kalla, sedangkan metode analisis yang digunakan dalam penelitian ini adalah analisis perkembangan Economic Value Added (EVA), Net Operating Profit After Tax (NOPAT) dan The purpose of this study was to determine the performance of the Economic Value Added (EVA), which is achieved by the company PT. Hadji Kalla...

  6. A Low-mass Exoplanet Candidate Detected by K2 Transiting the Praesepe M Dwarf JS 183

    Science.gov (United States)

    Pepper, Joshua; Gillen, Ed; Parviainen, Hannu; Hillenbrand, Lynne A.; Cody, Ann Marie; Aigrain, Suzanne; Stauffer, John; Vrba, Frederick J.; David, Trevor; Lillo-Box, Jorge; Stassun, Keivan G.; Conroy, Kyle E.; Pope, Benjamin J. S.; Barrado, David

    2017-04-01

    We report the discovery of a repeating photometric signal from a low-mass member of the Praesepe open cluster that we interpret as a Neptune-sized transiting planet. The star is JS 183 (HSHJ 163, EPIC 211916756), with T eff = 3325 ± 100 K, M * = 0.44 ± 0.04 M ⊙, R * = 0.44 ± 0.03 R ⊙, and {log}{g}* = 4.82+/- 0.06. The planet has an orbital period of 10.134588 days and a radius of R P = 0.32 ± 0.02 R J. Since the star is faint at V = 16.5 and J = 13.3, we are unable to obtain a measured radial velocity orbit, but we can constrain the companion mass to below about 1.7 M J, and thus well below the planetary boundary. JS 183b (since designated as K2-95b) is the second transiting planet found with K2 that resides in a several-hundred-megayear open cluster; both planets orbit mid-M dwarf stars and are approximately Neptune sized. With a well-determined stellar density from the planetary transit, and with an independently known metallicity from its cluster membership, JS 183 provides a particularly valuable test of stellar models at the fully convective boundary. We find that JS 183 is the lowest-density transit host known at the fully convective boundary, and that its very low density is consistent with current models of stars just above the fully convective boundary but in tension with the models just below the fully convective boundary.

  7. ANALISIS HARGA POKOK PRODUKSI DAN PENERAPAN TARGET COSTING PADA UD WAJUKU MAKASSAR

    OpenAIRE

    -, CHAIDIR HAFID

    2017-01-01

    ABSTRAK Analisis Harga Pokok Produksi dan Penerapan Target Costing pada UD Wajuku Makassar The Analysis of The Cost of Goods Manufactured and Implementation of Target Costing in UD Wajuku Makassar Chaidir Hafid Asri Usman Syahrir Penelitian ini bertujuan untuk mengetahui perhitungan harga pokok produksi baju kaos polos sebelum dan setelah penerapan metode target costing pada UD Wajuku Makassar. Metode pengumpulan data yang digunakan adalah dokumentasi. Metode analisis dat...

  8. JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells.

    Science.gov (United States)

    Kiziltepe, Tanyel; Hideshima, Teru; Ishitsuka, Kenji; Ocio, Enrique M; Raje, Noopur; Catley, Laurence; Li, Chun-Qi; Trudel, Laura J; Yasui, Hiroshi; Vallet, Sonia; Kutok, Jeffery L; Chauhan, Dharminder; Mitsiades, Constantine S; Saavedra, Joseph E; Wogan, Gerald N; Keefer, Larry K; Shami, Paul J; Anderson, Kenneth C

    2007-07-15

    Here we investigated the cytotoxicity of JS-K, a prodrug designed to release nitric oxide (NO(*)) following reaction with glutathione S-transferases, in multiple myeloma (MM). JS-K showed significant cytotoxicity in both conventional therapy-sensitive and -resistant MM cell lines, as well as patient-derived MM cells. JS-K induced apoptosis in MM cells, which was associated with PARP, caspase-8, and caspase-9 cleavage; increased Fas/CD95 expression; Mcl-1 cleavage; and Bcl-2 phosphorylation, as well as cytochrome c, apoptosis-inducing factor (AIF), and endonuclease G (EndoG) release. Moreover, JS-K overcame the survival advantages conferred by interleukin-6 (IL-6) and insulin-like growth factor 1 (IGF-1), or by adherence of MM cells to bone marrow stromal cells. Mechanistic studies revealed that JS-K-induced cytotoxicity was mediated via NO(*) in MM cells. Furthermore, JS-K induced DNA double-strand breaks (DSBs) and activated DNA damage responses, as evidenced by neutral comet assay, as well as H2AX, Chk2 and p53 phosphorylation. JS-K also activated c-Jun NH(2)-terminal kinase (JNK) in MM cells; conversely, inhibition of JNK markedly decreased JS-K-induced cytotoxicity. Importantly, bortezomib significantly enhanced JS-K-induced cytotoxicity. Finally, JS-K is well tolerated, inhibits tumor growth, and prolongs survival in a human MM xenograft mouse model. Taken together, these data provide the preclinical rationale for the clinical evaluation of JS-K to improve patient outcome in MM.

  9. Dosimetry practice for irradiation of the Mediterranean fruit fly Ceratitis capitata (Wied.)

    International Nuclear Information System (INIS)

    Zavala, J.L.; Fierro, M.M.; Schwarz, A.J.; Orozco, D.H.; Guerra, M.

    1985-01-01

    In a sterile insect technique (SIT) programme the sterility of mass-reared insects, in our case Mediterranean fruit flies, is of primary importance. Mediterranean fruit fly pupae are irradiated in an AECL-CP-JS-7400 irradiator. Originally the capacity was 31,300 Ci, but because of the natural decay of cobalt, the actual source strength is 14,836 Ci. Thus, the dose with which the pupae are irradiated is 14.5 +- 1 krad (145 +- 10 Gy). A great risk in the daily release of sterile flies is that some batches of fertile flies may also be released. To ensure that this does not occur, continuous dosimetric check-ups have to routinely be carried out. Fricke dosimetry is ideal for this purpose because it has a range of response to doses of 4 to 40 krad (40 to 400 Gy) and because it is an economic and simple dosimetric system. (author)

  10. Analisis Komoditi Unggulan Subsektor Tanaman Pangan di Sumatera Utara Tahun 2010 – 2014

    OpenAIRE

    Sinaga, Terry Praganda

    2016-01-01

    Tujuan penelitian ini adalah untuk mengetahui perkembangan produksi komoditi tanaman pangan selama periode tersebut sehingga dapat menganalisis komoditi subsektor tanaman pangan yang menjadi unggulan di Sumatera Utara. Komoditi unggulan tersebut juga dijabarkan untuk setiap kabupatem/kota yang ada di Sumatera Utara. Metode yang digunakan yaitu secara Convenience Sampling, dan metode analisis data dengan menggunakan analisis Location Quotient. Hasil penelitian menyimpulkan ba...

  11. Phosphate-binding protein from Polaromonas JS666: purification, characterization, crystallization and sulfur SAD phasing

    Energy Technology Data Exchange (ETDEWEB)

    Pegos, Vanessa R.; Hey, Louis; LaMirande, Jacob; Pfeffer, Rachel; Lipsh, Rosalie; Amitay, Moshe; Gonzalez, Daniel; Elias, Mikael (JCT-Israel); (UMM); (CNRS-UMR)

    2017-05-25

    Phosphate-binding proteins (PBPs) are key proteins that belong to the bacterial ABC-type phosphate transporters. PBPs are periplasmic (or membrane-anchored) proteins that capture phosphate anions from the environment and release them to the transmembrane transporter. Recent work has suggested that PBPs have evolved for high affinity as well as high selectivity. In particular, a short, unique hydrogen bond between the phosphate anion and an aspartate residue has been shown to be critical for selectivity, yet is not strictly conserved in PBPs. Here, the PBP fromPolaromonasJS666 is focused on. Interestingly, this PBP is predicted to harbor different phosphate-binding residues to currently known PBPs. Here, it is shown that the PBP fromPolaromonasJS666 is capable of binding phosphate, with a maximal binding activity at pH 8. Its structure is expected to reveal its binding-cleft configuration as well as its phosphate-binding mode. Here, the expression, purification, characterization, crystallization and X-ray diffraction data collection to 1.35 Å resolution of the PBP fromPolaromonasJS666 are reported.

  12. Biodegradation of isoproturon using a novel Pseudomonas aeruginosa strain JS-11 as a multi-functional bioinoculant of environmental significance.

    Science.gov (United States)

    Dwivedi, Sourabh; Singh, Braj Raj; Al-Khedhairy, Abdulaziz A; Musarrat, Javed

    2011-01-30

    Biodegradation of phenylurea herbicide isoproturon was studied in soil microcosm bioaugmented with a novel bacterial strain JS-11 isolated from wheat rhizosphere. The molecular characterization based on 16SrDNA sequence homology confirmed its identity as Pseudomonas aeruginosa strain JS-11. The herbicide was completely degraded within 20 days at ambient temperature with the rate constant of 0.08 day(-1), following the first-order rate kinetics. In stationary phase, at a cell density of 6.5 × 10(9) CFU mL(-1), the bacteria produced substantially increased amounts of indole acetic acid (IAA) in the presence of tryptophan as compared with the control. Also, the bacteria exhibited a time-dependent increase in the amount of tri-calcium phosphate solubilization in Pikovskaya's medium. Further screening of the strain JS-11 for auxiliary activities revealed its remarkable capability of producing the siderophores and hydrogen cyanide (HCN), besides antifungal activity against a common phytopathogen Fusarium oxysporum. Thus, the versatile P. aeruginosa strain JS-11 with innate potential for multifarious biological activities is envisaged as a super-bioinoculant for exploitation in the integrated bioremediation, plant growth and disease management (IBPDM) in contaminated agricultural soils. Copyright © 2010 Elsevier B.V. All rights reserved.

  13. Tīmekļa lietotņu veiktspējas optimizācija AngularJS lietotnēs

    OpenAIRE

    Niedrītis, Andris

    2016-01-01

    Darbā Tīmekļa lietotņu veiktspējas optimizācija AngularJS lietotnēs tiek pētīts klienta puses lietotņu izstrādes ietvars AngularJS un tā tipiskākie veiktspējas trūkumi un izstrādātāju kļūdas, kā arī veidi kā risināt šīs kļūdas un uzlabot lietotņu veiktspēju. Pētījums balstās uz informāciju, kas atrodama paša ietvara oficiālajā dokumentācijā un pieredzējušu AngularJS lietotāju viedokļiem par šī ietvara potenciālajām problēmām un to risinājumiem. Pārsvarā tiek aplūkoti veidi kā veidot lietotne...

  14. Effects of the nitric oxide donor JS-K on the blood-tumor barrier and on orthotopic U87 rat gliomas assessed by MRI.

    Science.gov (United States)

    Weidensteiner, Claudia; Reichardt, Wilfried; Shami, Paul J; Saavedra, Joseph E; Keefer, Larry K; Baumer, Brunhilde; Werres, Anna; Jasinski, Robert; Osterberg, Nadja; Weyerbrock, Astrid

    2013-04-01

    Nitric oxide (NO) released from NO donors can be cytotoxic in tumor cells and can enhance the transport of drugs into brain tumors by altering blood-tumor barrier permeability. The NO donor JS-K [O(2)-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] releases NO upon enzymatic activation selectively in cells overexpressing glutathione-S-transferases (GSTs) such as gliomas. Thus, JS-K-dependent NO effects - especially on cell viability and vascular permeability - were investigated in U87 glioma cells in vitro and in an orthotopic U87 xenograft model in vivo by magnetic resonance imaging (MRI). In vitro experiments showed dose-dependent antiproliferative and cytotoxic effects in U87 cells. In addition, treatment of U87 cells with JS-K resulted in a dose-dependent activation of soluble guanylate cyclase and intracellular accumulation of cyclic guanosine monophosphate (cGMP) which was irreversibly inhibited by the selective inhibitor of soluble guanylate cyclase ODQ (1H-[1,2,4]oxadiazolo(4,3a)quinoxaline-1-one). Using dynamic contrast enhanced MRI (DCE-MRI) as a minimally invasive technique, we demonstrated for the first time a significant increase in the DCE-MRI read-out initial area under the concentration curve (iAUC60) indicating an acute increase in blood-tumor barrier permeability after i.v. treatment with JS-K. Repeated MR imaging of animals with intracranial U87 gliomas under treatment with JS-K (3.5 μmol/kg JS-K 3×/week) and of untreated controls on day 12 and 19 after tumor inoculation revealed no significant changes in tumor growth, edema formation or tumor perfusion. Immunohistochemical workup of the brains showed a significant antiproliferative effect of JS-K in the gliomas. Taken together, in vitro and in vivo data suggest that JS-K has antiproliferative effects in U87 gliomas and opens the blood-tumor barrier by activation of the NO/cGMP signaling pathway. This might be a novel approach to facilitate entry of therapeutic

  15. APLIKASI METODE-METODE AGGLOMERATIVE DALAM ANALISIS KLASTER PADA DATA TINGKAT POLUSI UDARA

    Directory of Open Access Journals (Sweden)

    Dewi Rachmatin

    2014-09-01

    Full Text Available ABSTRAK   Analisis Klaster merupakan analisis pengelompokkan data yang mengelompokkan data berdasarkan informasi yang ditemukan pada data. Tujuan dari analisis klaster adalah agar objek-objek di dalam satu kelompok memiliki kesamaan satu sama lain sedangkan dengan objek-objek yang berbeda kelompok memiliki perbedaan. Analisis klaster dibagi menjadi dua metode yaitu metode hirarki dan metode non-hirarki. Metode hirarki dibagi menjadi dua, yaitu metode agglomerative (pemusatan dan metode divisive (penyebaran. Metode-metode yang termasuk dalam metode agglomerative adalah Single Linkage Method, Complete Linkage Method, Average Linkage Method, Ward’s Method, Centroid Method dan Median Method. Pada artikel ini dibahas metode-metode agglomerative tersebut yang diterapkan pada data tingkat polusi udara. Masing-masing metode tersebut memberikan jumlah klaster yang berbeda.   Kata Kunci : Analisis Klaster, Single Linkage Method, Complete Linkage Method, Average Linkage Method, Ward’s Method, Centroid Method dan Median Method.     ABSTRACT Cluster analysis is an analysis of the data classification based on information found in the data.The objective of cluster analysis is that the objects in the group have in common with each other, while the different objects have different groups. Cluster analysis is divided into two methods : the method of non-hierarchical and hierarchical methods.Hierarchical method is divided into two methods, namely agglomerative methods (concentration and divisive methods (deployment. The methods included in the agglomerative method is Single Linkage Method, Complete Linkage Method, Average Linkage Method, Ward 's Method, Method and Median Centroid Method. In this article discussed the agglomerative methods were applied to the data rate of air pollution. Each of these methods provides a different number of clusters.   Keywords: Cluster Analysis , Single Linkage Method, Complete Linkage Method, Average Linkage Method, Ward

  16. Preoperative preparation of high-risk, specifically hyperimmunized canine renal allograft recipients with total-lymphoid irradiation and cyclosporine

    International Nuclear Information System (INIS)

    Rapaport, F.T.; Meek, A.G.; Arnold, A.N.; Miura, S.; Hayashi, R.; Strober, S.

    1987-01-01

    Hyperimmunized subjects are a particularly high-risk and rapidly growing group in the patient population awaiting renal transplantation. In a search for methods designed to ameliorate the prognosis in such cases, dogs of defined DLA genotype were sensitized with DLA incompatible skin allografts and injections of buffy coat. Each recipient was challenged with a renal allograft bearing the same DLA incompatibilities. Five dogs received kidney transplants, without any other treatment, and rejected their transplants at 2.5, 4, 5, 6, and 6.5 days, respectively. Another four dogs were given a 9-11-week course (1760 +/- 35 cGy) of total-lymphoid irradiation (TLI), followed by rabbit antithymocyte globulin (ATG); these animals rejected their renal allografts at 7, 8, 14, and 17 days, respectively. Five other dogs were treated with TLI and received cyclosporine (CsA) and methylprednisolone (MPd) daily until graft rejection. Their renal allografts survived for 7.5, 8.5, 20, 62, and 227 days, respectively. Renal allografts placed in normal recipients under the same conditions of donor-recipient DLA incompatibility had a mean survival time of 12.4 days (range: 10-18 days). At the time of transplantation, the specific anti-DLA antibody titers in the recipients were 81 to 243 in the untreated dogs; 27 to 81 in the TLI-ATG-treated group, and 3 to 243 in the TLI-CsA/MPd-treated group. The titers fell within 24-48 hr after renal transplantation, to 3 to 81 in the untreated sensitized dogs; they were 3 to 9 in the TLI-ATG-treated group, and were 9 to 243 in the TLI-CsA/MPd treated group. The cytotoxic antibody titers reached postoperative peaks of 6500 to 200,000 in the untreated dogs; 729 to 6500 in the TLI-ATG-treated dogs, and 243 to 6500 in the TLI-CsA/MPd-treated recipients

  17. Risk analysis; Analisis de riesgos

    Energy Technology Data Exchange (ETDEWEB)

    Baron, J H; Nunez McLeod, J; Rivera, S S [Universidad Nacional de Cuyo, Mendoza (Argentina). Instituto de Capacitacion Especial y Desarrollo de Ingenieria Asistida por Computadora (CEDIAC)

    1997-07-01

    This book contains a selection of research works performed in the CEDIAC Institute (Cuyo National University) in the area of Risk Analysis, with specific orientations to the subjects of uncertainty and sensitivity studies, software reliability, severe accident modeling, etc. This volume presents important material for all those researches who want to have an insight in the risk analysis field, as a tool to solution several problems frequently found in the engineering and applied sciences field, as well as for the academic teachers who want to keep up to date, including the new developments and improvements continuously arising in this field. [Spanish] Este libro contiene una seleccion de trabajos de investigacion realizados dentro del Instituto de Capacitacion Especial y Desarrollo de la Ingenieria Asistida por Computadora en el area del analisis de riesgos, con una orientacion hacia el estudio de incertidumbres y sensibilidad, confiabilidad de software, modelacion de accidentes severos, etc. Este volumen recoge un material de indudable importancia e interes para todos aquellos investigadores y profesionales que desean incursionar en este campo del analisis de riesgos como herramienta para la solucion de problemas frecuentemente encontrados en la ingenieria y las ciencias aplicadas, asi como para los academicos que desean mantenerse al dia, conociendo los nuevos desarrollos y tecnicas que constantemente aparecen en su area.

  18. ANALISIS PENGARUH KINERJA LINGKUNGAN TERHADAP KINERJA INDUSTRI KECIL

    Directory of Open Access Journals (Sweden)

    Sukirman -

    2012-03-01

    Full Text Available Tujuan penelitian adalah mengidentifikasi, menganalisis praktik pengelolaan lingkungan pada sentra industri kecil dibandingkan best practices dalam upaya meningkatkan kinerja lingkungan di Kabupaten Pati. Kajian difokuskan pada pengelolaan lingkungan secara efektif dengan melibatkan variabel inisiatif lingkungan, keterlibatan karyawan, dan integrasi dengan supplier. Populasinya adalah seluruh perusahaan Industri Kecil di Kabupaten Pati. Sampel berjumlah 97 perusahaan. Teknik sampling menggunakan kluster sampling, dengan sampel pada sentra industri kecil di Kabupaten Pati.  Analisis menggunakan analisis deskriptif dan analisis komparatif. Hasil penelitian menunjukkan praktik pengelolaan lingkungan pada sentra industri kecil di Kabupaten Pati belum dilaksanakan secara optimal. Sementara itu, variabel integrasi supplier berpengaruh langsung terhadap kinerja perusahaan.The purpose of this study is to identify and to analyze an environmental management practice which is compared to the best practices in order to improve environmental performance in the industrial centers in Pati District. This study focuses on managing the environment effectively by involving environmental initiative variables, employee involvement, and integration of suppliers. Population in this study was all small industrial enterprises in Pati regency which has 97 companies as data samples. Data were collected by using cluster sampling techniques, and samples were taken from small industrial centers in the District of Pati. Data were analyzed by using descriptive and comparative methods. Results of this study showed that environmental management practices in small industrial centers had not been implemented optimally. Meanwhile, supplier integration variables influenced directly toward corporate performance.

  19. Analisis Korelasi Kanonik Hubungan Perilaku Pemimpin dan Motivasi Kerja Karyawan

    Directory of Open Access Journals (Sweden)

    I Gusti Ayu Made Srinadi

    2014-06-01

    Full Text Available Kualitas pemimpin merupakan penentu keberhasilan organisasi yang dipimpin. Hubungan antara pemimpin dengan karyawannya merupakan hubungan saling ketergantungan yang umumnya tidak seimbang. Dalam proses interaksi yang terjadi antara pemimpin dan karyawan, berlangsung proses saling memengaruhi. Penelitian ini bertujuan untuk mencari hubungan perilaku pemimpin terhadap motivasi kerja karyawan dengan menggunakan analisis korelasi kanonik. Pengujian dengan menggunakan analisis korelasi kanonik menunjukkan bahwa perilaku pemimpin dengan motivasi karyawan memiliki keeratan hubungan dengan nilai korelasi kanonik sebesar 0,9058533. Faktor perilaku pemimpin yang paling tinggi berkorelasi dengan motivasi kerja karyawan di McDonald’s Kuta Beach adalah faktor kemampuan mengarahkan dan menghadapi karyawan dengan nilai korelasi yaitu sebesar 0,7619707.

  20. Analisis Korelasi Kanonik Hubungan Perilaku Pemimpin dan Motivasi Kerja Karyawan

    Directory of Open Access Journals (Sweden)

    I Gusti Ayu Made Srinadi

    2015-04-01

    Full Text Available Kualitas pemimpin merupakan penentu keberhasilan organisasi yang dipimpin. Hubungan antara pemimpin dengan karyawannya merupakan hubungan saling ketergantungan yang umumnya tidak seimbang. Dalam proses interaksi yang terjadi antara pemimpin dan karyawan, berlangsung proses saling memengaruhi. Penelitian ini bertujuan untuk mencari hubungan perilaku pemimpin terhadap motivasi kerja karyawan dengan menggunakan analisis korelasi kanonik. Pengujian dengan menggunakan analisis korelasi kanonik menunjukkan bahwa perilaku pemimpin dengan motivasi karyawan memiliki keeratan hubungan dengan nilai korelasi kanonik sebesar 0,9058533. Faktor perilaku pemimpin yang paling tinggi berkorelasi dengan motivasi kerja karyawan di McDonald’s Kuta Beach adalah faktor kemampuan mengarahkan dan menghadapi karyawan dengan nilai korelasi yaitu sebesar 0,7619707.

  1. ANALISIS KELAYAKAN FINANSIAL PROYEK NARROWNECK PRESS AND BLOW UNTUK PROSES PRODUKSIBOTOL MINUMAN BERENERGI DI PT. ABC

    Directory of Open Access Journals (Sweden)

    Toni MT Munthe

    2015-08-01

    Full Text Available PT. ABC merupakan salah satu pabrik yang memproduksi botol kemasan kaca. Penelitian ini bertujuan untuk mengetahui layak atau tidaknya rencana investasi pada proyek Narrow Neck Press and Blow secara finansial di PT. ABC pada periode bulan April 2014 hingga bulan Juni 2014. Analisis kelayakan finansial proyek Narrow Neck Press and Blow, menggunakan metode analisis Net Present Value, Internal Rate of Return, Payback Period dan Sensitivity Analysis. Perbedaan antara nilai sekarang dari semua kas masuk dengan nilai sekarang dari semua kas keluar dari suatu proyek atau suatu investasi diperoleh dengan metode NPV, sedangkan untuk mencari tingkat bunga yang menyamakan nilai sekarang dari aliran kas bersih dan investasi diperoleh dengan metode IRR. Metode analisis yang dapat digunakan untuk mengetahui berapa lamakah waktu yang diperlukan untuk menutup dana yang dikeluarkan untuk suatu proyek dapat diperoleh dengan metode Payback Period. Setelah itu, dilakukan pengujian menggunakan sensitivitas analisis untuk mengetahui tingkat sensitivitas untuk tiap-tiap parameter terhadap persentase kenaikan dan penurunan. Dari hasil analisis data diperoleh nilai NPV sebesar Rp. 1.179.728.649.900,06, nilai IRR sebesar 56,36% dan periode pengembalian terletak pada 2 tahun 2 bulan 9 hari. Dengan menggunakan analisis sensitivitas dapat diketahui bahwa proyek ini sangat sensitif terhadap penurunan volume produksi. Berdasarkan hasil perhitungan, titik impas akan dicapai apabila volume produksi 213.403.267 unit per tahun atau 88,92% dari volume produksi awal. Nilai ini menunjukkan bahwa apabila volume produksi pada suatu periode mengalami penurunan lebih dari 11,08% dari volume produksi awal, maka investasi tersebut akan merugikan.

  2. Analisis Industri Ritel Di Indonesia

    OpenAIRE

    Soliha, Euis

    2008-01-01

    This article presents an overview the analisys of retail industry in Indonesia.Retail industry in Indonesia grow rapidly. Industrial presence of modern retailbasically exploits public shopping pattern especially middle-weight and to which donot want to mill around in traditional market. Analysis Five Forces is used toanalysis retail industry. Analysis five force is bargaining power of buyers,bargaining power of suppliers, threat of new entrants, threat of new substituteproducts, and rivalry a...

  3. Analisis Value Chain Di Industri Otomotif

    OpenAIRE

    Hendri, Hendri

    2017-01-01

    Penelitian ini untuk menganalisis industri otomotif. Tujuan dari penelitian ini adalah untuk menganalisis dan mengetahui aktivitas dan kondisi internal proses industri manufaktur dengan menggunakan value chain guna masukan dimasa akan datang bagi industri otomotif secara khusus. Value Chain merupakan rantai nilai yang dapat mengetahui kekuatan Perusahaan, keuntungan dan kesuksesan dari rantai aktivitas dalam Perusahaan atau industri manufaktur.Metode analisis menggunakan Statistika Deskript...

  4. The Analisis Sentimen Sosial Media Twitter Dengan Algoritma Machine Learning Menggunakan Software R

    Directory of Open Access Journals (Sweden)

    Jaka Aulia Pratama

    2017-10-01

    Full Text Available Media sosial adalah wadah untuk mengungkapkan opini terhadap suatu topik tertentu. Ketersediaan informasi dan opini dari para pengguna media sosial merupakan kumpulan dokumen data berupa teks yang amat sangat besar dan berguna untuk kepentingan penelitian maupun membuat suatu keputusan bagi pihak – pihak tertentu. Text Mining bisa didefinisikan sebagai proses penggalian informasi di mana pengguna berinteraksi dengan kumpulan dokumen dari waktu ke waktu dengan menggunakan suatu alat analisis. Analisis sentimen atau Opinion Mining adalah salah satu studi di bidang komputasi yang berhubungan dengan kasus publik mengenai opini, penilaian, sikap, dan emosi. Penelitian ini akan menggunakan metode Machine Learning pada analisis sentimen pengguna layanan jejaring sosial Twitter terhadap Donald Trump dan Barack Obama dalam 20000 tweets. Nilai akurasi metode Machine Learning yang diperoleh cukup tinggi yaitu 87.52% untuk Data Training dan 87.4% untuk Data Testing.

  5. Uncertainty and sensitivity analysis methodology in a level-I PSA (Probabilistic Safety Assessment); Analisis de incertidumbres y sensibilidad aen un APS (Analisis Probabilistico de Seguridad) nivel-I

    Energy Technology Data Exchange (ETDEWEB)

    Nunez McLeod, J E; Rivera, S S [Universidad Nacional de Cuyo, Mendoza (Argentina). Instituto de Capacitacion Especial y Desarrollo de Ingenieria Asistida por Computadora (CEDIAC)

    1997-07-01

    This work presents a methodology for sensitivity and uncertainty analysis, applicable to a probabilistic safety assessment level I. The work contents are: correct association of distributions to parameters, importance and qualification of expert opinions, generations of samples according to sample sizes, and study of the relationships among system variables and system response. A series of statistical-mathematical techniques are recommended along the development of the analysis methodology, as well different graphical visualization for the control of the study. (author) [Spanish] En este trabajo se presenta una metodologia de analisis de sensibilidad e incertidumbres, aplicable a un analisis probabilistico de seguridad (APS) de nivel I. En el cual se plantea: la adecuada asociacion de distribuciones a variables, la importancia y penalizacion de la opinion de expertos, la generacion de muestras y su tamano, y el estudio de las relaciones entre las variables del sistema y la respuesta de este. Ademas durante el desarrollo de la metodologia de analisis se recomiendan una serie de tecnicas estadistico-matematicas y tipos de visualizacion grafica para el control del estudio. (autor)

  6. Real-time imaging of the growth-inhibitory effect of JS399-19 on Fusarium.

    Science.gov (United States)

    Wollenberg, Rasmus D; Donau, Søren S; Nielsen, Thorbjørn T; Sørensen, Jens L; Giese, Henriette; Wimmer, Reinhard; Søndergaard, Teis E

    2016-11-01

    Real-time imaging was used to study the effects of a novel Fusarium-specific cyanoacrylate fungicide (JS399-19) on growth and morphology of four Fusarium sp. This fungicide targets the motor domain of type I myosin. Fusarium graminearum PH-1, Fusarium solani f. sp. pisi 77-13-4, Fusarium avenaceum IBT8464, and Fusarium avenaceum 05001, which has a K216Q amino-acid substitution at the resistance-implicated site in its myosin type I motor domain, were analyzed. Real-time imaging shows that JS399-19 inhibits fungal growth but not to the extent previously reported. The fungicide causes the hypha to become entangled and unable to extend vertically. This implies that type I myosin in Fusarium is essential for hyphal and mycelia propagation. The K216Q substitution correlates with reduced susceptibility in F. avenaceum. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Determination of diacylhydrazines-type insect growth regulator JS-118 residues in cabbage and soil by high performance liquid chromatography with DAD detection.

    Science.gov (United States)

    Hu, J-Y; Deng, Z-B; Qin, D-M

    2009-12-01

    JS-118 is a diacylhydrazines-type insect growth regulator used extensively in China now. An analytical method for residues determination of JS-118 in cabbage and soil samples by high performance liquid chromatography with DAD detection was established and optimized. Primary secondary amine solid phase extraction cartridge was used for sample preparation. Mean recoveries for the analyte ranged from 96.6% to 107.0% with CV value less than 4.7%. The limit of quantification is 0.01 mg/kg. Direct confirmation of JS-118 residues in samples was realized by high performance liquid chromatography-mass spectrometry. The proposed method is simple, rapid and reliable to perform and could be utilized for monitoring of pesticides residues.

  8. Analysis of the parameters relating to failures above the clavicles in patients treated by postoperative irradiation for squamous cell carcinomas of the oral cavity or oropharynx

    International Nuclear Information System (INIS)

    Feldman, M.; Fletcher, G.H.

    1982-01-01

    One hundred and two patients with squamous cell carcinoma of the oral cavity or oropharynx were treated from January 1955 through August 1976 with surgical excision followed by irradiation. Twelve patients had T 2 lesions and 90 had T 3 or T 4 lesions. Failures above the clavicles were associated with disease present at the margins of resection, location of the recurrence close to the periphery, or outside of the irradiated portals. Failures in the neck essentially were a result of no elective irradiation. In patients with disease present at the margins of resection, there is a risk both of gross residual disease and hypoxic microscopic disease left behind; 4500 to 5000 rad is not adequate for a significant control rate. In situations where there is definite disease at the margin of resection, 6500 rad, or in specific situations, 7000 rad, should be given through reduced fields

  9. Control of selected VVER components life time SKODA JS a.s. experience

    International Nuclear Information System (INIS)

    Zdebor, J.; Pribulla, E.

    2005-01-01

    Experience from the operation of nuclear power plants with type VVER reactors has shown that the life time management of a number of nuclear reactor components is technically as well as with respect to safety substantiated even at the time which exceeds their originally designed life time. To accept such solution it was necessary to develop and implement a number of programs based on which it was possible to evaluate the actual condition of monitored equipment. It is a condition allowing to adopt solution concerning the possibility of their further operation. Experience from the manufacture of 21 sets of reactor equipment for VVER 440 and 3 sets VVER 1000 has been gathered in SKODA JS a.s. which have been completed by experience from service activities performed at operated nuclear power plants. Analyses of manufacturing data and in-service inspection results completed by a lot of laboratory tests have become the basis for the development of selected VVER components life time management programs. The paper focuses on the life time management of those VVER components which SKODA JS a.s. has most experience with. (authors)

  10. Irradiation of mangoes as a quarantine treatment

    International Nuclear Information System (INIS)

    Bustos R, M.E.; Enkerlin H, W.; Toledo A, J.; Reyes F, J.; Casimiro G, A.

    1991-06-01

    This research project was conducted following guidelines of research protocols for post-harvest treatments developed by the United States Department of Agriculture CUSA. Laboratory bioassays included the irradiation of mangoes infested with third instar larvae of Anastrepha serpentina (Wied), A. ludens (Loew), A. obliqua (Macquart) and Ceratitis capitata (Wied) , at doses from 10 to 250 Gy. Irradiation doses were applied using a Co-60 AECL Model JS-7400 irradiator. The design was chosen to obtain a maximum to minimum ratio equal to, or less than, 1.025. C. capitata was the species most tolerant to irradiation. A dose of 60 Gy applied to third instar fruit fly larvae sterilized this species and prevented emergence of adults of the other three species. A dose of 250 Gy was required to prevent emergence of C. capitata. In fertility tests using emerged adults of A . Iudens, and A. obliqua a dose of 30 Gy gave 45 % and 27 % fertility, respectively. Adults of A. serpentina that emerged, died before reaching sexual maturity. The confirmatory tests, at probit-9 security level, were done at 100 Gy for the three species of Anastrepha and at 150 Gy for C. capitata. The quality of mangoes irradiated up to 1000 Gy was evaluated by chemical, physiological, and sensorial tests. The determination of vitamin C indicated that there was no loss of the nutritive value of the fruit. It also was observed that fruit metabolism was not accelerated since no significant increase in respiration or transpiration was registered and consumers accepted both treated and untreated fruit in the same way. (Author)

  11. Irradiation of mangoes as a quarantine treatment

    Energy Technology Data Exchange (ETDEWEB)

    Bustos R, M E; Enkerlin H, W; Toledo A, J; Reyes F, J; Casimiro G, A

    1991-06-15

    This research project was conducted following guidelines of research protocols for post-harvest treatments developed by the United States Department of Agriculture CUSA. Laboratory bioassays included the irradiation of mangoes infested with third instar larvae of Anastrepha serpentina (Wied), A. ludens (Loew), A. obliqua (Macquart) and Ceratitis capitata (Wied) , at doses from 10 to 250 Gy. Irradiation doses were applied using a Co-60 AECL Model JS-7400 irradiator. The design was chosen to obtain a maximum to minimum ratio equal to, or less than, 1.025. C. capitata was the species most tolerant to irradiation. A dose of 60 Gy applied to third instar fruit fly larvae sterilized this species and prevented emergence of adults of the other three species. A dose of 250 Gy was required to prevent emergence of C. capitata. In fertility tests using emerged adults of A . Iudens, and A. obliqua a dose of 30 Gy gave 45 % and 27 % fertility, respectively. Adults of A. serpentina that emerged, died before reaching sexual maturity. The confirmatory tests, at probit-9 security level, were done at 100 Gy for the three species of Anastrepha and at 150 Gy for C. capitata. The quality of mangoes irradiated up to 1000 Gy was evaluated by chemical, physiological, and sensorial tests. The determination of vitamin C indicated that there was no loss of the nutritive value of the fruit. It also was observed that fruit metabolism was not accelerated since no significant increase in respiration or transpiration was registered and consumers accepted both treated and untreated fruit in the same way. (Author)

  12. Echography and operated or irradiated breasts; Echographie et seins operes, irradies

    Energy Technology Data Exchange (ETDEWEB)

    Baratte, B.; Neel-Paprocki, V.; Grumbach, Y. [Centre Hospitalier Universitaire, 80 - Amiens (France)

    1995-12-31

    Since 1985, the medical survey of patients operated even for benign or malignant initial breast injury comprises an X-ray mammal examination and a mammal echography. Until 1993, the echography was performed with a CGR scanner device with a 7.5 MHz barrette. Now, a GE RTX 400 device with two MHz barrettes is used, one with a removable interposition equipment and the other for echography controlled punctures. Echographic modifications are dependent on the treatment used: partial or complete surgery and/or irradiation. Early and late normal echographic aspects must be known. Echography is particularly efficient for the diagnosis of post-surgery hematoma, lymphocele and abscess and for the detection of recurrence in the case of dense breast. Its combination with X-ray radiography can solve most diagnosis problems. In any case of doubt, puncture or tru-cut biopsy must be done, and if not sufficient, the use of NMR imaging remains of great help. (J.S.).

  13. Analisis Kebijakan dan Efektivitas Organisasi

    Directory of Open Access Journals (Sweden)

    Amir Syarifudin Kiwang

    2015-05-01

    Full Text Available Penerapan Peraturan Gubernur Nusa Tenggara Timur Nomor 8 Tahun 2011 tentang Organisasi dan Tata Kerja Unit Pelaksana Teknis Pendidikan dan Pelatihan Koperasi dan Usaha Mikro Kecil dan Menengah pada Dinas Koperasi dan Usaha Mikro Kecil dan Menengah Provinsi Nusa Tenggara Timur adalah dalam rangka untuk meningkatkan efektivitas kerja organisasi pada UPT Diklat Koperasi dan UMKM. Penelitian ini berusaha untuk melihat dampak kebijakan organisasi terhadap efektivitas organisasi dengan menggunakan enam elemen variabel dari kebijakan dan praktik manajemen. Keenam elemen tersebut adalah penetapan tujuan strategis, pencarian dan pemanfaatan sumber daya, lingkungan prestasi, proses komunikasi, kepemimpinan dan pengambilan keputusan, serta adaptasi dan inovasi organisasi. Penelitian kualitatif ini menggunakan pendekatan studi kasus. Teknik analisis data yang digunakan adalah analisis data model Miles dan Huberman, yang terdiri atas reduksi data, display/penyajian data, dan kesimpulan/verifikasi. Hasil penelitian menunjukkan bahwa efektivitas organisasi pada UPT Diklat koperasi dan UMKM belum berjalan secara baik, hal ini dapat dilihat dari beberapa hal antara lain, belum adanya tenaga spesialisasi pengelola diklat dan tenaga khusus (sarjana di bidang perkoperasian dan kondisi lingkungan kerja (lingkungan prestasi pada UPT Diklat koperasi dan UMKM yang belum efektif. Penempatan pegawai juga belum tepat, mutasi ke UPT Diklat Koperasi dan UMKM tidak memperhatikan latar belakang pendidikan dan spesialisasi/keahlian pegawai sehingga membutuhkan waktu dalam proses penyesuaian serta menurunkan jumlah pelaksanaan diklat dikarenakan keterbatasan alokasi dana.

  14. ANALISIS PERIKANAN HUHATE DI PERAIRAN LARANTUKA, FLORES

    Directory of Open Access Journals (Sweden)

    Mohamad Adha Akbar

    2016-11-01

    Full Text Available Informasi mengenai beberapa aspek perikanan huhate sangat diperlukan sebagai bahan untuk perencanaan pengelolaan perikanan yang berkelanjutan. Penelitian ini dilakukan di Larantuka, Flores Timur pada tahun 2014 dengan tujuan untuk menganalisis perikanan huhate sebagai salah satu tulang punggung perikanan TCT. Kegiatan penelitian diprioritaskan pada analisis unit alat tangkap, daerah penangkapan, komposisi hasil tangkapan dan estimasi Total Faktor Produktivitas (TFP perikanan huhate. Basis data pengukuran adalah himpunan  data pendaratan dan observasi lapang. Hasil penelitian menunjukan bahwa karakteristik armada terdiri dari kapal yang terbuat dari fibreglass dengan kisaran bobot kapal 6 - 30 GT. Daerah penangkapan di sekitar perairan Laut Sawu dan Laut Flores. Hasil tangkapan utama didominansi oleh cakalang (Katsuwonus pelamis sebanyak 82%, juwana tuna (Thunnus spp. 17% dan tongkol (Auxis spp. 1% serta hasil tangkapan ikutan lemadang (Coryphaena hippurus dan marlin (Makaira spp. < 1%. Hasil analisis tangkapan per unit upaya (CPUE memberikan nilai rata-rata sebesar 1,1 ton/trip (0,4-1,7 ton/trip dengan nilai tertinggi terjadi pada Februari, sedangkan terendah terjadi pada Januari. Hasil penelitian menunjukkan terdapat hubungan yang signifikan antara tren bulanan CPUE dan nilai TFP.

  15. ANALISIS PENGELOLAAN LINGKUNGAN PERMUKIMAN DI KABUPATEN SOPPENG

    Directory of Open Access Journals (Sweden)

    Bakhrani Rauf

    2016-08-01

    Full Text Available Penelitian ini  bertujuan untuk mendeskripsikan pengelolaan lingkungan permukiman di Kabupaten Soppeng pada aspek: (1 penyediaan dan penanganan lahan terbuka hijau (open space; (2 penyediaan dan penanganan drainase; (3  penanganan sampah; (4 penyediaan dan penanganan pembuangan veses (septic tank. Jenis penelitian ini adalah penelitian kuantitatif dengan pendekatan survei.  Sampel wailayah penelitian ini adalah satu RW di ibu kota kabupaten dan satu RW di desa yang dipilih dengan metode purpossive sampling,  yaitu RW yang sudah maju di ibu kota kabupaten dan RW yang tertinggal di desa. Responden sebanyak 50 kepala keluarga yakni masing-masing 25 kepala keuarga di setiap RW, dipilih dengan  systematic random sampling.  Teknik pengumpulan data yang dilakukan adalah melakukan observasi langsung dan dilengkapi dengan wawancara terhadap responden. Analisis yang digunakan adalah analisis deskriptif. Hasil penelitian menunjukkan bahwa pengelolaan lingkungan permukiman di Kabupaten Soppeng pada aspek: (1 ketersediaan dan penanganan lahan terbuka hijau (open space ditemukan belum memadai; (2 ketersediaan drainase (air kotor dan air hujan ditemukan belum memadai; (3 Penanganan sampahbelum memadai; dan (4 penanganan veses dan penyediaan septic tankbelum memadai.

  16. Analisis Perbandingan Material Slab Beton Pada Perkerasan Apron Dengan Menggunakan Program Bantu Elemen Hingga

    Directory of Open Access Journals (Sweden)

    Hendrawan Setyo Warsito

    2016-04-01

    Full Text Available Kekuatan slab beton sangat dipengaruhi oleh jenis material yang dipakai. Jenis material yang dimaksud adalah material beton dengan menggunakan PC (Portland Cement dan penggunaan geopolimer dalam komposisi campuran slab beton. Beton geopolimer merupakan beton yang ramah lingkungan. Permasalahan lain yang timbul adalah letak roda pesawat tidak selalu berada pada titik yang sama disuatu permukaan slab beton apron. Pada tugas akhir ini dimaksudkan untuk menganalisis suatu slab beton yang dibebani roda pesawat dengan campuran variasi material beton dan variasi letak roda pesawat pada slab beton dengan program bantu metode elemen hingga. Dengan data pergerakan pesawat, spesifikasi apron bandara Juanda kondisi eksisting. Dilakukan perhitungan tebal slab beton menggunakan software FAARFIELD dan diperoleh tebal slab beton sebesar 442,5 mm. Dari analisis program bantu elemen hingga dapat diperoleh tegangan pada slab beton yang ditimbulkan oleh pembebanan roda pesawat. Hasil validasi dari analisis tegangan menggunakan program bantu elemen hingga dengan analisis Westergaard yaitu memiliki nilai tegangan yang hampir sama pada ketebalan slab beton 450mm. Nilai tegangan tiap-tiap material beton menunjukan nilai tebal slab beton yang diijinkan untuk tipe pesawat tertentu. Dari analisis menggunakan program bantu elemen hingga tebal slab beton yang diijinkan untuk material slab beton PC yaitu sebesar 425mm. Sedangkan untuk material beton geopolimer yaitu sebesar  415 mm.

  17. Functional genomics provides insights into the role of Propionibacterium freudenreichii ssp. shermanii JS in cheese ripening.

    Science.gov (United States)

    Ojala, Teija; Laine, Pia K S; Ahlroos, Terhi; Tanskanen, Jarna; Pitkänen, Saara; Salusjärvi, Tuomas; Kankainen, Matti; Tynkkynen, Soile; Paulin, Lars; Auvinen, Petri

    2017-01-16

    Propionibacterium freudenreichii is a commercially important bacterium that is essential for the development of the characteristic eyes and flavor of Swiss-type cheeses. These bacteria grow actively and produce large quantities of flavor compounds during cheese ripening at warm temperatures but also appear to contribute to the aroma development during the subsequent cold storage of cheese. Here, we advance our understanding of the role of P. freudenreichii in cheese ripening by presenting the 2.68-Mbp annotated genome sequence of P. freudenreichii ssp. shermanii JS and determining its global transcriptional profiles during industrial cheese-making using transcriptome sequencing. The annotation of the genome identified a total of 2377 protein-coding genes and revealed the presence of enzymes and pathways for formation of several flavor compounds. Based on transcriptome profiling, the expression of 348 protein-coding genes was altered between the warm and cold room ripening of cheese. Several propionate, acetate, and diacetyl/acetoin production related genes had higher expression levels in the warm room, whereas a general slowing down of the metabolism and an activation of mobile genetic elements was seen in the cold room. A few ripening-related and amino acid catabolism involved genes were induced or remained active in cold room, indicating that strain JS contributes to the aroma development also during cold room ripening. In addition, we performed a comparative genomic analysis of strain JS and 29 other Propionibacterium strains of 10 different species, including an isolate of both P. freudenreichii subspecies freudenreichii and shermanii. Ortholog grouping of the predicted protein sequences revealed that close to 86% of the ortholog groups of strain JS, including a variety of ripening-related ortholog groups, were conserved across the P. freudenreichii isolates. Taken together, this study contributes to the understanding of the genomic basis of P. freudenreichii

  18. Analisis Model Penelusuran Backward Chaining dalam Mendeteksi Tingkat Kecanduan Game pada Anak

    Directory of Open Access Journals (Sweden)

    Anastasya Latubessy

    2017-10-01

    Full Text Available Game addiction rate can be detected by applying expert system. This study developed a model of game addiction analysis using backward chaining. This model uses six types of game addiction behavior, among others, salience, euphoria, conflict, tolerance, withdrawal, relapse and reinstatement. Someone is said to be addicted to the game if it meets at least three types of game addiction behavior. Testing the validity of the model is done by testing the closeness of the agreement between the model analysis and expert analysis, resulting in a value of 0.78 which means having a strong agreement. Tingkat kecanduan game dapat dideteksi dengan mengaplikasikan sistem pakar. Penelitian ini mengembangkan model analisis tingkat kecanduan game menggunakan backward chaining. Model ini menggunakan enam jenis perilaku kecanduan game antara lain, salience, euphoria, conflict, tolerance, withdrawal, relapse dan reinstatement. Seseorang dikatakan kecanduan game jika memenuhi paling sedikit tiga jenis perilaku kecanduan game. Pengujian validitas model dilakukan dengan menguji keeratan kesepakatan antara analisis model dan analisis pakar, menghasilkan nilai 0,78 yang berarti memiliki keeratan kesepakatan kuat.

  19. Estetika Tari Minang dalam Kesenian Randai Analisis Tekstual-Kontekstual

    Directory of Open Access Journals (Sweden)

    Sri Rustiyanti

    2013-03-01

    Full Text Available ABSTRACT   This paper reveals textual and contextual Randai, among other things, an analysis of Gerak Ga­ lombang Randai, an analysis of the character of Anak Randai, and at the end of the study series, to reveal the values contained in Randai as a cultural reality, which in principle is an inseparable part of the existence of Minangkabau community as the cultural support. The variety of motion used in Gerak Galombang Randai is not only a decoration of the motion beauty (tangible, but it also can be translated, as well as a symbol or emblem that has educational meanings (intangible, and can be an example of the daily life of the indigenous Minangkabau society.   Keywords: Minang Dance aesthetic, Randai, textual­contextual analysis     ABSTRAK   Tulisan ini mengungkap teksual dan kontekstual Randai, di antaranya, analisis terhadap gerak galombang Randai, analisis karakter tokoh anak Randai, dan sebagai akhir dari rang- kaian penelitian ini, mengungkapkan nilai-nilai yang terdapat pada Randai sebagai realitas budaya, yang pada prinsipnya merupakan bagian yang tak dapat dipisahkan dari eksistensi masyarakat Minangkabau sebagai penyangga kebudayaan. Ragam gerak yang digunakan dalam gerak galombang Randai itu kiranya tidak hanya sekedar hiasan keindahan gerak be- laka (tangibel, namun ia dapat diterjemahkan, sekaligus merupakan simbol atau lambang yang bermakna  mendidik (intangibel, dan dapat   menjadi teladan dalam kehidupan se- hari-hari dalam masyarakat adat di Minangkabau.   Kata Kunci: estetika Tari Minang, Randai, analisis tekstual-kontekstual

  20. Uptake and incorporation of labeled tryptophan isomers into IAA in the jsR1 mutant of Lemna gibba

    International Nuclear Information System (INIS)

    Baldi, B.G.; Maher, B.R.; Cohen, J.D.

    1989-01-01

    Analyses of the IAA-overproducing mutant of Lemna have been initiated in order to study in vivo biosynthesis of IAA. Using radiolabelled tryptophan isomers prepared from commercial sources of 14 C-D,L tryptophan by chiral separation kinetics of uptake of L and D tryptophan were determined for sterile cultures of individual jsR 1 four-frond colonies. Over a 24 h period, about 50% of the radioactivity from 14 C-L-TRP in media, or about 25% from 14 C-D-TRP, was found in the plant tissue. Maximal rates of uptake were seen in the first six hors for both isomers. Endogenous levels of tryptophan determined in jsR 1 as measures of pool sizes in vivo show 5 to 10 ug/g FW total tryptophan with less than 1% in the D isomer form. Information on uptake and endogenous pool sizes of tryptophan isomers is being used for feeding of stable isotope labeled tryptophan ( 13 C, 14 N) to jsR 1 at physiological levels. Analyses of incorporation of label into IAA using GC-MS and high resolution mass spectrometry are currently underway

  1. Nitric oxide released from JS-K induces cell death by mitotic catastrophe as part of necrosis in glioblastoma multiforme.

    Science.gov (United States)

    Günzle, Jessica; Osterberg, Nadja; Saavedra, Joseph E; Weyerbrock, Astrid

    2016-09-01

    The nitric oxide (NO) donor JS-K is specifically activated by glutathione S-transferases (GSTs) in GST-overexpressing cells. We have shown the induction of cell death in glioblastoma multiforme (GBM) cells at high JS-K doses but the mechanism remains unclear. The aim of this study was to determine whether NO-induced cell death is triggered by induction of apoptotic or necrotic pathways. For the first time, we demonstrate that NO induces cell death via mitotic catastrophe (MC) with non-apoptotic mechanisms in GBM cells. Moreover, the level of morphological changes indicating MC correlates with increased necrosis. Therefore, we conclude that MC is the main mechanism by which GBM cells undergo cell death after treatment with JS-K associated with necrosis rather than apoptosis. In addition, we show that PARP1 is not an exclusive marker for late apoptosis but is also involved in MC. Activating an alternative way of cell death can be useful for the multimodal cancer therapy of GBM known for its strong anti-apoptotic mechanisms and drug resistance.

  2. Criticality safety analyses in SKODA JS a.s

    International Nuclear Information System (INIS)

    Mikolas, P.; Svarny, J.

    1999-01-01

    This paper describes criticality safety analyses of spent fuel systems for storage and transport of spent fuel performed in SKODA JS s.r.o.. Analyses were performed for different systems both at NPP site including originally designed spent fuel pool with a large pitch between assemblies without any special absorbing material, high density spent fuel pool with an additional absorption by boron steel, depository rack for fresh fuel assemblies with a very large pitch between fuel assemblies, a container for transport of fresh fuel into the reactor pool and a cask for transport and storage of spent fuel and container for final storage depository. required subcriticality has been proven taking into account all possible unfavourable conditions, uncertainties etc. In two cases, burnup credit methodology is expected to be used. (Authors)

  3. ANALISIS PERBAIKAN SISTEM PENTANAHAN TELEKOMUNIKASI

    Directory of Open Access Journals (Sweden)

    Umar Umar

    2015-04-01

    Hasil dari penelitian ini adalah perbaikan sistem pentanahan site Kampung Baru dengan menggunakan konfigurasi single point connection window (SPCW, untuk mengamankan sistem telekomunikasi dari kebocoran arus dan petir serta imbasnya.  Perbaikan sistem pentanahan di site Kampung Baru menggunakan banyak elektroda yang membentuk persegi dikarenakan topografi tempat di sana yang memungkinkan dan efektif adalah menggunakan sistem tersebut. Berdasarkan hasil analisis dan perhitungan perbaikan sistem di site Kampung Baru, didapatkan nilai perhitungan sistem pentanahan adalah 1.34 Ohm serta pengukurannya 1.21-1.25 Ohm.

  4. Implementation of CMS Central DAQ monitoring services in Node.js

    CERN Document Server

    Vougioukas, Michail

    2015-01-01

    This report summarizes my contribution to the CMS Central DAQ monitoring system, in my capacity as a CERN Summer Students Programme participant, from June to September 2015. Specifically, my work was focused on rewriting – from Apache/PHP to Node.js/Javascript - and optimizing real-time monitoring web services (mostly Elasticsearch-based but also some Oracle-based) for the CMS Data Acquisition (Run II Filterfarm). Moreover, it included an implementation of web server caching, for better scalability when simultaneous web clients use the services. Measurements confirmed that the software developed during this project has indeed a potential to provide scalable services.

  5. Postoperative irradiation in carcinoma of the prostate

    International Nuclear Information System (INIS)

    Pilepich, M.V.; Walz, B.J.; Baglan, R.J.

    1984-01-01

    Twenty-eight patients received postoperative radiotherapy with curative intent following either radical prostatectomy (18 patients) or enucleative prostatectomy (10 patients). In patients undergoing radical prostatectomy, the indications for postoperative radiotherapy included positive margins in 13, close margins in 2, and seminal vesicle involvement in 3 patients. The majority of patients (82%) received total dose to the prostatic bed in excess of 6500 rad. In over 80% of the patients, the pelvic lymphatics are also treated (to a total dose of 4000-5000 rad). All of the patients irradiated after radical prostatectomy clinically remained disease-free locally. Approximately one-half of the patients in both the enucleation and radial prostatectomy groups developed evidence of distant metastases. The complications of treatment have been comparable to those in patients treated with radiotherapy only. The continence status has not been affected significantly. All patients with incontinence following completion of radiotherapy had documented impairment of continence prior to radiotherapy. Postoperative radiotherapy administered following either radical or enucleative prostatectomy was tolerated well and resulted in excellent local control

  6. ANALISIS DAYA SAING KEDELAI INDONESIA

    Directory of Open Access Journals (Sweden)

    Sarwono Sarwono

    2014-09-01

    Full Text Available RCA (Revealed Comparative Advantage index of soybean in Indonesia from 1983 up to 2013 is less than one, mostly. It means that the competitiveness of soybean in Indonesia is low. The purpose of this study is to analyze the factors influence the soybean competitiveness. OLS (Ordinary Least Square was used as the analysis method. Hypotheses test based on that analysis model is not bias, so that, classic divergence test is needed. It is for getting the Best Linier Unbiased Estimator (BLUE appraisal. T statistic and F statistic were also applied. The result of this research shows that production and export have positive and significant influence. In addition, exchange rate and government policy do not influence the Indonesia soybean competitiveness.Indeks RCA (Revealed Comparative Advantage kedelai Indonesia dari tahun 1983-2013 kecenderungan bernilai kurang dari satu yang berarti daya saing kedelai Indonesia rendah.Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi daya saing kedelai Indonesia.Metode analisis yang digunakan adalah Ordinary Least Square (OLS.Pengujian hipotesis berdasarkan model analisis tersebut tidak bias maka perlu dilakukan uji penyimpangan klasik yang tujuannya agar diperoleh penaksiran yang bersifat Best Linier Unbiased Estimator (BLUE.Pengujian statistik menggunakan uji t statistikdan uji f statistik.Hasil penelitian ini menunjukkan bahwa produksi dan ekspor berpengaruh secara positif dan signifikan terhadap daya saing kedelai Indonesia. Nilai tukar rupiah dan kebijakan pemerintah tidak berpengaruh terhadap daya saing kedelai Indonesia.

  7. Analisis Pengaruh Display Interior Terhadap Perilaku Pembelian Impulsif Konsumen Indomaret Pontianak

    Directory of Open Access Journals (Sweden)

    Ana Fitriana

    2016-07-01

    Full Text Available Pembelian impulsif adalah kecenderungan membeli produk atau jasa dengan tidak terencana, selanjutnya ketika pembelian sering tidak terencana, maka umumnya konsumen membeli produk atau jasa yang tidak terdaftar dalam daftar belanja. Sejalan dengan tujuan pemasar, pembelian tidak terencana ini berdampak sangat positif bagi pihak perusahaan. Salah satu perilaku konsumen yang sangat penting adalah perilaku belanja impulsif. Penelitian ini bertujuan untuk mengetahui pengaruh display interior pada Indomaret Pontianak terhadap impulsive buying konsumennya. Metode penelitian yang digunakan adalah penelitian kuantitatif. Populasi penelitian ini adalah konsumen Indomaret Pontianak, sebanyak 100 responden dipilih secara accidental sampling sebagai sampel penelitian. Metode pengumpulan data yang digunakan adalah metode pengumpulan data primer dengan teknik pengumpulan data kuesioner. Teknik analisis data yang digunakan adalah uji validitas dan reliabilitas, analisis koefisien determinasi, analisis regresi berganda dan uji hipotesis.Hasil perhitungan data menggunakan SPSS for windows ver 16 menunjukan secara simultan pengaruh display interior terhadap impulsive buying diketahui berpengaruh sebesar 61,31%. Sedangkan 38,69% dipengaruhi oleh faktor lain yang tidak diteliti didalam penelitian ini. Secara parsial tiga variabel bebas yaitu pengadaan barang, pengelompokan barang, dan penyusunan barang dan pencahayaan mempunyai pengaruh signifikan terhadap Impulsive buying.   Kata kunci — Pengadaan barang, Pengelompokan barang, Penyusunan barang dan pencahayaan, Perilaku Pembelian Impulsif

  8. High abundance of JS-1- and Chloroflexi-related Bacteria in deeply buried marine sediments revealed by quantitative, real-time PCR.

    Science.gov (United States)

    Blazejak, Anna; Schippers, Axel

    2010-05-01

    Sequences of members of the bacterial candidate division JS-1 and the classes Anaerolineae and Caldilineae of the phylum Chloroflexi are frequently found in 16S rRNA gene clone libraries obtained from marine sediments. Using a newly designed quantitative, real-time PCR assay, these bacterial groups were jointly quantified in samples from near-surface and deeply buried marine sediments from the Peru margin, the Black Sea, and a forearc basin off the island of Sumatra. In near-surface sediments, sequences of the JS-1 as well as Anaerolineae- and Caldilineae-related Bacteria were quantified with significantly lower 16S rRNA gene copy numbers than the sequences of total Bacteria. In contrast, in deeply buried sediments below approximately 1 m depth, similar quantities of the 16S rRNA gene copies of these specific groups and Bacteria were found. This finding indicates that JS-1 and Anaerolineae- and Caldilineae-related Bacteria might dominate the bacterial community in deeply buried marine sediments and thus seem to play an important ecological role in the deep biosphere.

  9. Pengembangan Sistem Informasi Geografis Berbasis Node.JS untuk Pemetaan Mesin dan Tracking Engineer dengan Pemanfaatan Geolocation pada PT IBM Indonesia

    Directory of Open Access Journals (Sweden)

    RACHMAT FAJRIN

    2017-09-01

    Full Text Available PT IBM memiliki banyak klien di Indonesia, ini membuat persebaran produk (dalam hal ini mesin atm yang semakin meluas di wilayah Indonesia. Hal ini memicu PT IBM untuk menempatkan engineer dibanyak wilayah untuk memenuhi kebutuhan services dan maintenance. Untuk itu dalam penelitian ini dikembangkan sebuah sistem informasi geografis untuk pemetaan mesin dan tracking engineer dengan pemanfaatan geolocation yang bertujuan untuk menampilkan peta digital beserta lokasi mesin dan engineer di seluruh Indonesia, yang akan memudahkan PT IBM dalam pemberian tugas kepada engineer untuk services dan maintenance ke lokasi mesin terdekat. Sistem ini dibangun menggunakan beberapa software open source yaitu, Node.JS dan Express.JS yang merupakan server-side javascript web platform, Handlebars untuk template engine, MySQL sebagai database storage, Postman yang berfungsi sebagai API (Application Program Interface testing, Google Maps API untuk implementasi peta digital dan juga Firebase Cloud Messaging (FCM untuk platform mengirim notifikasi dari web ke device engineer.Pengembangan Sistem Informasi Geografis Berbasis Node.JS untuk Pemetaan Mesin dan Tracking Engineer dengan Pemanfaatan Geolocation pada PT IBM Indonesia

  10. Risk analysis in the chemical industry; Analisis de riesgos en la industria quimica

    Energy Technology Data Exchange (ETDEWEB)

    Rea Soto, Rogelio; Sandoval Valenzuela, Salvador [Instituto de Investigaciones Electricas, Temixco, Morelos (Mexico)

    2000-07-01

    The Instituto de Investigaciones Electricas has a group of risk analysis (GAR), specialized in the most advanced methodologies to apply them in diverse industries of the productive sector, such as the nuclear, the oil and the chemical industries. In this work the integrated methodology that the GAR uses to make risk analysis in the chemical and oil industries is described. These analyses have as an objective to make a meticulous evaluation of the system design, the operation practices, the maintenance and inspection policies and the emergency plans. [Spanish] El Instituto de Investigaciones Electricas cuenta con un grupo de analisis de riesgo (GAR), especializado en las metodologias mas avanzadas para aplicarlas en diversas industrias del sector productivo, como lo son la nuclear, la petrolera y la quimica. En este trabajo se describe la metodologia integrada que el GAR utiliza para realizar analisis de riesgos en las industrias quimica y petrolera. Estos analisis tienen como objetivo realizar una minuciosa evaluacion del diseno del sistema, las practicas de operacion, las politicas de mantenimiento e inspeccion y los planes de emergencia.

  11. Analisis Reduksi Intensitas Cahaya Pada Smartphones’ Screen Protector Dan Dampaknya Pada Mata

    Directory of Open Access Journals (Sweden)

    Bhekti Kumorowati

    2017-04-01

    Full Text Available Analisis reduksi intensitas cahaya yang melewati screen protector dan identifikasi kemampuan screen protector sebagai pelindung mata dilakukan dengan mengukur reduksi intensitas cahaya menggunakan luxmeter, kemudian menetapkan fokus bahasan yang mencakup kemampuan cahaya menembus screen protector dan analisis fisis screen protector sebagai pelindung mata. Peran sebagai pelindung mata dikaji melalui pendekatan peristiwa polarisasi yaitu proses terserapnya sebagian arah getar cahaya. Dihasilkan sebagian arah getar cahaya layar smartphone sebelum masuk ke mata akan terserap oleh screen protector sehingga dapat memperlambat terjadinya degenerasi makula. Rekomendasi pemilihan screen protector bergantung pada besarnya koefisien atenuasi (koefisien penyerapan yang dimiliki masing-masing screen protector. Koefisien atenuasi terbesar dimiliki oleh screen protector jenis anti spy.

  12. Kekule.js: An Open Source JavaScript Chemoinformatics Toolkit.

    Science.gov (United States)

    Jiang, Chen; Jin, Xi; Dong, Ying; Chen, Ming

    2016-06-27

    Kekule.js is an open-source, object-oriented JavaScript toolkit for chemoinformatics. It provides methods for many common tasks in molecular informatics, including chemical data input/output (I/O), two- and three-dimensional (2D/3D) rendering of chemical structure, stereo identification, ring perception, structure comparison, and substructure search. Encapsulated widgets to display and edit chemical structures directly in web context are also supplied. Developed with web standards, the toolkit is ideal for building chemoinformatics applications over the Internet. Moreover, it is highly platform-independent and can also be used in desktop or mobile environments. Some initial applications, such as plugins for inputting chemical structures on the web and uses in chemistry education, have been developed based on the toolkit.

  13. Microbiological and sensory evaluation of the shelf-life of irradiated chicken breast meat

    International Nuclear Information System (INIS)

    Miyagusku, L.; Chen, F.; Leitao, M.F. de F.; Baffa, O.

    2003-01-01

    Kraft paper boxes containing 10 expanded polystyrene trays with 200g skinless deboned chicken breast each were irradiated with 60 Co source of a Nordion JS7500 irradiator. The trays were previously wrapped with polyethylene film. The samples were exposed to 1.5; 3.0 and 7.0 kGy doses in the static mode at 0º and 180º in relation to the irradiation beam. Set of 18 alanine+paraffin dosimeters per treatment were distributed inside the boxes for evaluation of irradiation dose homogeneity. A separeted dose calibration curve was obtained by irradiating in the range of 1 to 10kGy. After the irradiation, the chicken breasts were stored at 5±1ºC for 39 days and were analysed microbiologically in total psychrotrophic aerobic bacteria, total mesophilic aerobic bacteria, molds and yeasts, Pseudomonas spp, Enterobacteriaceae, lactic bacteria counts and E.coli during the storage period. The results revealed a linear behaviour of the alanine+paraffin dosimeters in the range of 1 to 10kGy irradiation. In regard to the microbiological aspect, compared to the shelf-life of 5 days for the controls, there were a increasing of 1.75; 4.40 e 7.0 times shelf-life for chicken breasts irradiated with 1.5; 3.0 and 7.0kGy, respectively. There was an increasing change of the smell of burnt as the irradiation doses increased. Thus, 3kGy dose was considered as the ideal dose to assure a longer shelf-life to the product, without perceptible changes in the aspect [pt

  14. Analisis Termal High Pressure Feedwater Heater di PLTU PT. XYZ

    Directory of Open Access Journals (Sweden)

    Maria Ulfa Damayanti

    2017-01-01

    Full Text Available Abstrak- PT. XYZ mengoperasikan tiga unit Pembangkit Listrik Tenaga Uap (PLTU unit 3, 7 dan 8 berkapasitas 2.030 MegaWatt. Pada PLTU Paiton unit 7 dan 8 terdapat delapan buah feedwater heater yaitu empat buah Low Pressure Water Heater (LPWH, tiga buah High Pressure Water Heater (HPWH, dan sebuah dearator. Pada PLTU Paiton unit 7 dan 8 terdapat kerusakan pada HPWH 6 yang menyebabkan penurunan efisiensi dari siklus secara keseluruhan. Penurunan efisiensi dapat terjadi karena temperatur feedwater sebelum masuk ke boiler terlalu rendah, sehingga kalor yang dibutuhkan oleh boiler untuk memanaskan feedwater meningkat. Oleh karena itu konsumsi batubara akan meningkat dan menyebabkan terjadi kenaikan biaya operasional harian dalam sistem pembangkit. Dari data Divisi Produksi PT. XYZ Unit 7 dan 8 diperoleh spesifikasi HPWH 6, 7, dan 8 dan propertis fluida dalam HPWH 6, 7, dan 8. Data tersebut digunakan sebagai dasar analisis termal yang meliputi performa masing-masing HPH. Tahap selanjutnya dalam analisis termal adalah memvariasikan beban 25%, 50%, 75%, 100%, dan 105%. Tahap terakhir analisis adalah menghitung performa dengan variasi sumbatan (plug 5%, 10%, 15%, dan 20% sesuai dengan variasi beban. Hasil yang didapatkan dari penelitian tugas akhir ini adalah nilai effectiveness tertinggi tercapai pada pembebanan 100% serta menghasilkan pressure drop tertinggi pada pembebanan 105%, nilai effectiveness terbesar serta nilai pressure drop terkecil terjadi pada zona Condensing, serta sumbatan (plugging pada HPH akan menyebabkan penurunan nilai effectiveness dan kenaikan pressure drop sisi tube.

  15. Irradiation of bovine meat: effect of heme-iron concentration

    International Nuclear Information System (INIS)

    Mistura, Liliana Perazzini Furtado

    2002-01-01

    The irradiation is often used, nowadays, for meat conservation and it is important to know how much this process interferes with the nutritional quality of the meat. In this study round cut meat, ground and steaks (from a local supermarket) was irradiated with doses of O; 1; 2; 3; 4; 5; 7,5 and 10 kGy (JS-7500 Nordium Inc -Canada) and the interference of irradiation and the process of food preparation on heme-iron (H Fe) content was determined. Half of the sample was kept raw and the other half was grilled in a pre-warmed oven at 250 deg C for 9 min and a controlled humidity of 70%. The chemical composition, the total iron (T Fe) (EM) and the heme iron concentration were determined (Hornsey,1956) and the sensorial quality evaluated. The average T Fe concentration of raw and ground , ground and grilled, raw steaks and grilled steak meat, on dry and degreased basis was 113 mug/g, 121 mug/g , 91 mug/g and 77 mug/g; and the H Fe concentration 105 mug/g (93% of T Fe) , 88 mug/g (73% of T Fe), 90 mug/g (99% of T Fe) and 52 mug/g (68% of T Fe) respectively. Data were evaluated by ANOVA with fixed effects and multiple comparisons. The irradiation neither altered the chemical composition nor the proportion of heme iron of meat. The preparation conditions (temperature, cooking time, environment humidity, meat presentation) of the sample interfered more with the heme iron content than the irradiation. With the sensorial analysis we verified that meats irradiated with doses of 3 kGy were better evaluated in softness and succulency attributes than the others. Meat submitted to irradiation doses up to 3 kGy were accepted by the specialists' panel. (author)

  16. Analisis Kinerja Local Area Network Menggunakan Router.

    OpenAIRE

    Hutahaean, Yosua

    2012-01-01

    Perangkat internetworking menawarkan komunikasi di antara segmen Local Area Network (LAN). Ada empat tipe utama perangkat internetworking ini: repeater, bridge, router, dan gateway. Perangkat ini dibedakan atas dasar system lapisan Open System Interconnection (OSI) yang digunakan, berfungsi sebagai media komunikasi dari LAN ke LAN. Pada Tugas Akhir ini penulis tertarik untuk membahas analisis kinerja Local Area Network (LAN) menggunakan Router yang menggunakan sistem antrian M/M/1 dimana j...

  17. Application of standard softWare of the CDC-6500 interactive graphic therminal for representation of spiral scanning data and event saving

    International Nuclear Information System (INIS)

    Nehrguj, B.; Ososkov, G.A.

    1978-01-01

    A system of programs, based on a standard graphic display software, is developed which enables the user to display the results of spiral scanning using a terminal keyboard and a FILTR program. Quality assessment of filtering is also available. The use of a cursor which provides a certain feedback between the display and the CDC-6500 computer provides good capabilities for the investigation of the filtering program failures and saves the most interesting events. To speed up scanning of events, a special program is written which performs pre-filtration and reduces 4 to 5 fold the amount of source numerical data of track projections. Its flowchart is based on the well-known method of cords, which allows to save 10-12 events/hour

  18. Honda WT20K1C 2 inch electric driven trash pump and Honda ES6500c generator

    International Nuclear Information System (INIS)

    1992-01-01

    Recovery of highly volatile hydrocarbon spills has always presented safety problems due to the explosive, flammable nature of the product being recovered. In an effort to increase safety, decrease spill response time, and improve recovery and/or pumping of hydrocarbons, an electric driven trash pump has been designed, developed, and tested. This pump has the capacity to recover and/or pump volatile and flammable substances such as condensate, gasoline, diesel fuel, and light gravity crude oil products in a safe manner. The pumping unit consists of an electric motor rated for use in hazardous locations, a trash pump with a Duraprene impeller and pump body, a motor/pump frame, and a Honda ES6500c generator that powers the pump motor through up to 100 feet of cable. A remote control switch is used to operate the unit so that workers can stay at least 30 m away while it is running. 5 figs

  19. Effect of salt-inducible kinase 2 on checkpoint in response to γ-ray irradiation

    International Nuclear Information System (INIS)

    Yin Jiaojiao; Zhou Lijun; Wang Yu; Liu Xiaodan; Gu Yongqing; Zhou Pingkun

    2014-01-01

    Objective: To investigate the effect of salt-induced kinase 2 (SIK2) in the G_2/M checkpoint in response to ionizing radiation and the possible mechanism. Methods: HeLa cells were irradiated with "6"0Co γ-rays. The cell model of knockdown SIK2 expression was constrcuted by transfecting HeLa cells with a pSicoR-based lentivirus vector of expressing SIK2 shRNA by lipofectamin 2000. Western blot and flow cytometry were performed to measure the changes of SIK2 protein level and cell cycle distribution. The phosphorylated histone protein H3 on Ser 10 was used as a molecular marker of mitotic cells for detecting the function of G2/M checkpoint. Results: The expression level of SIK2 protein increased in HeLa cells after "6"0Co γ-ray irradiation. A cell model of knockdown SIK2 expression was successfully generated by transfecting the specific shRNA against SIK2. Depression of SIK2 significantly increased the cellular sensitivity at 1, 2, 4, 6 Gy post-irradiation (t = -3.445, -2.581, -3.251, -2.553, P < 0.05), and led cells to release earlier from the G_2/M boundary arrest compared to control cells at 5, 6 h post-irradiation(t = 4.341, 6.500, P < 0.05). Western blot analysis indicated that the irradiation-induced phosphorylated CHK2/T68 in SIK2 knock-down cells was earlier than that in control cells. Conclusions: salt-induced kinase 2 (SIK2) participates in the regulation of G_2/M checkpoint induced by ionizing radiation and affects cellular radiosensitivity. (authors)

  20. Analisis Penerimaan PAD Pada Dinas Perikanan dan Peternakan Kabupaten Tebo

    Directory of Open Access Journals (Sweden)

    Eko Purnarianto

    2016-06-01

    Full Text Available Abstract. This study aims to analyze potential, efficiency, effectivity and contribution of PAD admission at Department of Fishery and Animal Husbandry in Tebo Regencyincluding the strategy establishment to increase its revenue.The analysis used is a potential formula, efficiency ratio, effectivity ratio, contributions ratio and SWOT analysis.The results shows that the potential revenue of retribution slaughterhouse (RPH, the potential sales of livestock, and potential sales fishery product are beyond the current target. The efficiency level of retribution slaughterhouse (RPH and sales of fishery product is poor, but the sales of livestock is very efficient. Effectivity level of livestock and fishery product sales are low, whileretribution slaughterhouses(RPH is not effective regarded to its potential  but in the contrary for its target. Contribution of PAD admission of Fishery and Animal Husbandry Department is very low regarded Tebo Regency PAD. The result of SWOT analysis of retribution slaughter house (RPH admission using WO (Weakness-Opportunity strategy, livestock sales using SO (Strength-Oppurtunity strategy, and fishery product sales using ST (strength-threat strategy. Keywords: Retribution SlaughterHouse (RPH, Sales of Fishery, Livestock Sales, SWOT Analysis   Abstrak. Penelitian ini bertujuan untuk menganalisis potensi, efisiensi, efektivitas dan kontribusi penerimaan PAD pada Dinas Perikanan dan Peternakan Kabupaten Teboserta menetapkan strategi untuk peningkatan penerimaan PAD. Analisis yang digunakan adalah rumus potensi, rasio efisiensi, rasio efektivitas, rasio kontribusi dan analisis SWOT.Hasil penelitian menunjukkan bahwa potensi penerimaan retribusi rumah potong hewan (RPH, potensi penjualan hasil peternakan, potensi  penjualan hasil perikanan lebih besar dari target yang telah ditetapkan. Tingkat efisiensi retribusi RPH dan penjualan hasil perikanan tidak efisien, penjualan hasil peternakan sangat efisien. Tingkat

  1. [Construction and rescue of infectious cDNA clone of pigeon-origin Newcastle disease virus strain JS/07/04/Pi].

    Science.gov (United States)

    Zhu, Yan-Mei; Hu, Zeng-Lei; Song, Qing-Qing; Duan, Zhi-Qiang; Gu, Min; Hu, Shun-Lin; Wang, Xiao-Quan; Liu, Xiu-Fan

    2012-01-01

    Based on the complete genome sequence of pigeon-origin Newcastle disease virus strain JS/07/04/ Pi(genotype VIb), nine overlapped fragments covering its full-length genome were amplified by RT-PCR. The fragments were connected sequentially and then inserted into the transcription vector TVT7/R resulting in the TVT/071204 which contained the full genome of strain JS/07/04/Pi. The TVT/071204 was co-transfected with three helper plasmids pCI-NP, pCI-P and pCI-L into the BSR cells, and the transfected cells and culture supernatant were inoculated into 9-day-old SPF embryonated eggs 60 h post-transfection. The HA and HI tests were conducted following the death of embryonated eggs. The results showed that the allantoic fluids obtained were HA positive and the HA could be inhibited by anti-NDV serum which indicated that the strain JS/07/04/Pi was rescued successfully. The rescued virus rNDV/071204 showed similar growth kinetics to its parental virus in CEF. The successful recovery of this strain would contribute to the understanding of the host-specificity of pigeon-origin NDV and to the development of the novel vaccines against the NDV infection in pigeons.

  2. Genome Sequence of an Endophytic Fungus, Fusarium solani JS-169, Which Has Antifungal Activity.

    Science.gov (United States)

    Kim, Jung A; Jeon, Jongbum; Park, Sook-Young; Kim, Ki-Tae; Choi, Gobong; Lee, Hyun-Jung; Kim, Yangsun; Yang, Hee-Sun; Yeo, Joo-Hong; Lee, Yong-Hwan; Kim, Soonok

    2017-10-19

    An endophytic fungus, Fusarium solani strain JS-169, isolated from a mulberry twig, showed considerable antifungal activity. Here, we report the draft genome sequence of this strain. The assembly comprises 17 scaffolds, with an N 50 value of 4.93 Mb. The assembled genome was 45,813,297 bp in length, with a G+C content of 49.91%. Copyright © 2017 Kim et al.

  3. Induced absorption spectra of the infrared fundamental band of molecular deuterium at 77 K: S1( J)+S0( J) transitions

    International Nuclear Information System (INIS)

    Gillard, P.G.; Prasad, R.D.G.; Reddy, S.P.

    1984-01-01

    The collision-induced spectra of the fundamental band of normal D 2 in the high frequency region 3200--3700 cm -1 were recorded for gas densities in the range 80--140 amagat at 77 K with a 2 m absorption cell. The contribution to the intensity of the band in this region comes from the high frequency wings of quadrupolar transitions S 1 ( J) and Q 1 ( J)+S 0 ( J) with J = 0 and 1, and from the group of transitions S 1 (2) and Q 1 ( J)+S 0 (2) with J = 0, 1, and 2 as well as from the relatively weaker double rotational transitions of the type S 1 ( J)+S 0 ( J); the latter transitions arise from the intermolecular interaction between the anisotropic component of the polarizability of one of the colliding pairs of molecules and the quadrupole field of the other. The experimental profiles were analyzed by assuming appropriate line shape functions and using the theoretical matrix elements of the quadrupole moment, isotropic polarizability, and anisotropy of polarizability of the D 2 molecule. From this analysis the characteristic half-width parameters delta/sub q/2 and delta/sub q/4 of the quadrupolar transitions and the binary and ternary absorption coefficients of the S 1 ( J)+S 0 ( J) transitions have been obtained. The experimental value of the binary absorption coefficient of S 1 (0)+S 0 (0) is (2.2 +- 0.1) x 10 -9 cm -1 amagat -2 and the corresponding theoretical value is 1.53 x 10 -9 cm -1 amagat -2

  4. Perbandingan Penilaian Saham Dengan Metode Analisis Fundamental Dan Analisis Tehknical, Penggorengan Saham, Serta Keputusan Penilaian Saham Jika Hasil Berlawanan Arah Untuk Kedua Metode Analisis Pada Saham Bakrie Group Untuk Periode 2005- 2009

    OpenAIRE

    Harwaningrum, Miranti

    2016-01-01

    Beberapa tahun belakangan ini, dunia investasi mengalami peningkatan. Hal ini dapat terlihat dari data rata-rata perdagangan saham yang dimiliki oleh Bapepam. Salah satu jenis instrumen investasi yang sering diminati oleh investor adalah saham. Apabila dibandingkan dengan obligasi, saham memiliki expected return yang lebih tinggi. Namun, saham memiliki resiko yang lebih tinggi bila dibandingkan dengan obligasi. Untuk melakukan penilaian saham ada dua analisis yang dapat dilakukan, yaitu funda...

  5. ANALISIS MODEL PREDIKSI AWAL MUSIM HUJAN DI SULAWESI SELATAN

    Directory of Open Access Journals (Sweden)

    Alimatul Rahim

    2016-03-01

    Full Text Available Model prediksi awal musim hujan merupakan salah satu kunci yang dapat digunakan untuk mengurangi resiko kegagalan panen padi yang disebabkan oleh faktor iklim di provinsi Sulawesi Selatan. Model prediksi awal musim hujan dibangun  dengan menggunakan data curah hujan observasi Sulawesi Selatan dan anomali suhu muka laut di kawasan Pasifik dan perairan Sulawesi. Pada studi ini dilakukan analisis pemilihan stasiun hujan observasi, penentuan awal musim hujan, analisis komponen utama dan pengelompokan, analisis korelasi awal musim hujan terhadap anomali suhu muka laut, pembangunan model untuk prediksi awal musimhujan dan verifikasi model.Hasil analisis awal musim hujan menunjukkan setiap stasiun hujan mempunyai perbedaan awal musim hujan dengan rata-rata jatuh pada Julian Date (JD ke-348 (14 Desember. Berdasarkan hasil analisis PCA dan cluster, diperoleh bahwa di Sulawesi Selatan terbagi menjadi 3 cluster wilayah. Cluster 1 mempunyai pola hujan lokal, sedangkan cluster 2 dan 3 mempunyai pola hujan monsun. Pada peta korelasi antara awal musim hujan di Sulawesi Selatan dan anomali suhu muka laut menunjukkan bahwa terdapat korelasi nyata(r≥0.5 antara kawasan Pasifik dan Laut Sulawesi pada cluster 1 dan 2 pada bulan Juni Juli Agustus September(JJAS. Sedangkan pada cluster 3, korelasi nyata hanya pada bulan Juni di perairan Sulawesi. Model prediksi AMH terbaik, pada cluster 2 terdapat di domain prediktor kawasan pasifik dengan nilai r=0.82, sedangkan pada cluster 1 dan 3, terdapat di domain perairan Sulawesi dengan nilai r=0.78 dan r-0.48. Verifikasi model terpilih pada cluster 3 mempunyai RMSE = 3, sedangkan cluster 1 dan 2, nilai RMSE berturut-turut sebesar 16 dan 29.   Model prediction of rainy season onset is one of the keys to reduce the risk of paddy haverst failure because of climate factor in South Sulawesi province. The model prediction for rainy season onset was build using rainfall data in South Sulawesi and SST anomaly in Pacific Ocean and

  6. La financial education nella regione Puglia: analisi e prospettive di intervento

    OpenAIRE

    A. Garzoni; V. Nastasi

    2010-01-01

    Analisi del contesto e delle principali tematiche di financial education affrontate a livello internazionale e nazionale, valutazione delle opportunità e degli aspetti critici, il progetto pilota nella regione Puglia e le nuove idee di progetto da realizzare

  7. Text Mining Untuk Analisis Sentimen Review Film Menggunakan Algoritma K-Means

    Directory of Open Access Journals (Sweden)

    Setyo Budi

    2017-02-01

    Full Text Available Kemudahan manusia didalam menggunakan website mengakibatkan bertambahnya dokumen teks yang berupa pendapat dan informasi. Dalam waktu yang lama dokumen teks akan bertambah besar. Text mining merupakan salah satu teknik yang digunakan untuk menggali kumpulan dokumen text sehingga dapat diambil intisarinya. Ada beberapa algoritma yang di gunakan untuk penggalian dokumen untuk analisis sentimen, salah satunya adalah K-Means. Didalam penelitian ini algoritma yang digunakan adalah K-Means. Hasil penelitian menunjukkan bahwa akurasi K-Means dengan dataset digunakan 300 positif dan 300 negatif  akurasinya 57.83%,  700 dokumen positif dan 700  negatif akurasinya 56.71%%, 1000 dokumen positif dan 1000  negatif akurasinya 50.40%%. Dari hasil pengujian disimpulkan bahwa semakin besar dataset yang digunakan semakin rendah akurasi K-Means.   Kata Kunci : Text Mining, Analisis Sentimen, K-Means, Review Film 

  8. Analisis Nilai Perusahaan pada Implementasi Program Kepemilikan Saham pada Karyawan/Manajemen

    Directory of Open Access Journals (Sweden)

    Dwitya Aribawa

    2016-12-01

      Penelitian ini bertujuan menganalisis economic value added (EVA sebelum dan sesudah implementasi program kepemilikan saham pada karyawan/ manajemen dengan objek penelitian ini adalah perusahaan publik yang menggunakan kebijakan ESOP/MSOP sebagai sarana benefit/incentive berupa pembagian sebagian saham untuk karyawan/ manajemen. Variabel yang digunakan sebagai indikator nilai perusahaan adalah EVA. Nilai EVA dianggap sebagai indikator yang kompleks dan mempertimbangkan faktor resiko (beta dari perusahaan. Perusahaan yang dianalisis adalah perusahaan yang listing di Bursa Efek Indonesia. Terdapat 17 perusahaan yang layak untuk dilakukan analisis berdasarkan kriteria yang ditentukan peneliti. Pengumpulan dan data dianalisis secara pooling, hal ini melihat dari tidak dibedakannya perusahaan berdasarkan industri (multi industri. Paired sample test digunakan untuk menguji hipotesis pada penelitian dan sebelumnya dilakukan uji normalitas data. Hasil analisis bahwa hasil perbandingan rata-rata EVA sebelum dan sesudah implementasi program kepemilikan saham pada karyawan/manajemen terdapat perbedaan yag signifikan.

  9. PENGGUNAAN METODE STRUCTURAL EQUATION MODELLING UNTUK ANALISIS FAKTOR YANG MEMPENGARUHI MOTIVASI BELAJAR MAHASISWA FIP UMJ

    Directory of Open Access Journals (Sweden)

    Ririn Widiyasari

    2018-02-01

    Full Text Available Tujuan yang ingin dicapai dalam penelitian ini adalah mengetahui faktor apa saja  yang mempengaruhi motivasi belajar mahasiswa, apakah terdapat pengaruh yang signifikan antara cara belajar, fasilitas belajar dan lingkungan belajar terhadap motivasi belajar mahasiswa, serta faktor mana yang paling berpengaruh terhadap motivasi belajar mahasiswa. Jumlah sampel dalam penelitian ini adalah 192 mahasiswa (FIP UMJ angkatan tahun 2013-2015 yang aktif mengikuti perkuliahan. Metode penelitian yang dilakukan adalah metode kuantitatif survey. Metode pengambilan data menggunakan  kuesioner dengan skala likert. Metode analisis data yang digunakan adalah analisis deskriptif, dan analisis  Structural Equation Modeling (SEM berbantuan program LISREL 8.3. Uji hipotesis yang digunakan dalam penelitian ini adalah uji Chi-square dan uji t. Hasil penelitian menunjukkan bahwa variabel cara belajar memiliki kontribusi yang paling besar, selanjutnya variabel kedua yang berkontribusi meningkatkan motivasi belajar adalah lingkungan belajar dan terakhir fasilitas belajar memberikan pengaruh yang paling kecil terhadap motivasi belajar. Jadi, variabel laten cara belajar dan lingkungan belajar berpengaruh positif terhadap motivasi belajar dan fasilitas belajar berpengaruh negatif terhadap motivasi belajar.

  10. ANALISIS IMPOR BERAS DI INDONESIA

    Directory of Open Access Journals (Sweden)

    Ratih Kumala Sari

    2014-10-01

    Full Text Available Abstrak ___________________________________________________________________ Salah satu kebijakan pemerintah untuk memenuhi kebutuhan beras yaitu dengan menggenjot produksi beras dalam negeri. Namun dengan semakin meningkatnya jumlah penduduk akan meningkatkan permintaan terhadap beras dan upaya peningkatan produktivitas dalam negeri tidak dapat memenuhi kebutuhan beras dalam negeri. Sehingga untuk menutupi kekurangan tersebut pemerintah mengambil keputusan untuk melakukan impor beras dari negara lain. Akan tetapi pada kenyataannya impor beras dilakukan ketika data statistik menunjukkan bahwa Indonesia sedang mengalami surplus beras. Penelitian ini bertujuan untuk mengetahui faktor-faktor apa saja yang mempengaruhi impor beras di Indonesia. Metode analisis yang digunakan adalah analisis regresi linier berganda dengan model Error Correction Model (ECM. Berdasarkan hasil penelitian disimpulkan bahwa secara parsial maupun secara bersama-sama produksi beras, konsumsi beras, harga beras dalam negeri dan nilai tukar rupiah terhadap dollar AS berpengaruh dan signifikan terhadap impor beras di Indonesia. Abstract ___________________________________________________________________ One of the government’s policy to fulfill the need of rice is to boost the domestic production. However, by increasing the population, the demand of rice will also increase and the effort of increasing the domestic productivity cannot supply domestic rice need. So, to cover the shortage the government make decision to import rice from other countries. Yet, in fact importing rice is occurred when the statistical data showed that the supply of rice in Indonesia is surplus. The purpose of this research is necessary to study the factors which influence the import of rice in Indonesia. The analysis method used is multiple linear regression analysis model with Error Correction Model (ECM. Based on the research proven that partially or jointly the production, the consumption, the

  11. ANALISIS LITERASI EKONOMI

    Directory of Open Access Journals (Sweden)

    Peter Garlans Sina

    2012-10-01

    Full Text Available Abstract: Analysis of Economic Literacy. The aim of this research is as an effort to increase economic literacy for individuals and households who want to achieve prosperity. Therefore, the obligation of improving the economic literacy needs to be done in a well-planned manner and come from the strong intention to learn in order to improve the economic literacy. It could have an effect on the assets accumulation, a better debt management, as a protection, as well as to increase savings and managing spending intelligently.   Keyword: economic literacy, asset, debt, protection, saving, spending   Abstrak: Analisis Literasi Ekonomi. Tulisan ini bertujuan sebagai upaya meningkatkan literasi ekonomi bagi individu maupun rumah tangga yang menginginkan mencapai kesejahteraan. Oleh karena itu, kewajiban meningkatkan literasi ekonomi perlu dilakukan secara terencana dan diawali dari niat untuk belajar meningkatkan literasi ekonomi karena dapat berefek pada akumulasi aset, pengelolaan utang yang tepat, proteksi, meningkatkan tabungan dan cerdas mengelola pengeluaran.   Kata kunci: literasi ekonomi, aset, utang, proteksi, menabung, pengeluaran

  12. Echography and operated or irradiated breasts

    International Nuclear Information System (INIS)

    Baratte, B.; Neel-Paprocki, V.; Grumbach, Y.

    1995-01-01

    Since 1985, the medical survey of patients operated even for benign or malignant initial breast injury comprises an X-ray mammal examination and a mammal echography. Until 1993, the echography was performed with a CGR scanner device with a 7.5 MHz barrette. Now, a GE RTX 400 device with two MHz barrettes is used, one with a removable interposition equipment and the other for echography controlled punctures. Echographic modifications are dependent on the treatment used: partial or complete surgery and/or irradiation. Early and late normal echographic aspects must be known. Echography is particularly efficient for the diagnosis of post-surgery hematoma, lymphocele and abscess and for the detection of recurrence in the case of dense breast. Its combination with X-ray radiography can solve most diagnosis problems. In any case of doubt, puncture or tru-cut biopsy must be done, and if not sufficient, the use of NMR imaging remains of great help. (J.S.)

  13. Analisis Safety System dan Manajemen Risiko pada Steam Boiler PLTU di Unit 5 Pembangkitan Paiton, PT. YTL

    Directory of Open Access Journals (Sweden)

    Luluk Kristianingsih

    2013-09-01

    Full Text Available Pembangkit listrik tenaga uap (PLTU merupakan pembangkit listrik yang banyak digunakan di Indonesia. Salah satu bagian dari sistem PLTU yang memiliki risiko bahaya tinggi adalah boiler, oleh karena itu diperlukan adanya analisis bahaya dan safety system sebagai langkah pencegahan bahaya pada boiler. Analisis bahaya dalam penelitian ini dilakukan menggunakan metode HAZOP. Node yang dipakai adalah economizer, steam drum, superheater, dan reheater yang merupakan komponen utama penyusun boiler. Guide word dan deviasi ditentukan berdasarkan control chart yang dibentuk oleh data proses masing-masing komponen selama bulan Maret 2013. Estimasi likelihood dilakukan berdasarkan data maintenance dari work order PT YTL selama 5 tahun, sedangkan estimasi consequences dilakukan berdasarkan kriteria risiko yang ditimbulkan serta berdasarkan control chart. Hasil perkalian likelihood dan consequences dengan risk matrix menghasilkan kriteria risiko dari komponen. Berdasarkan hasil analisis, diperoleh hasil bahwa komponen yang memiliki risiko bahaya paling besar adalah level transmitter steam drum dengan deviasi berupa less level, yaitu dengan kriteria likelihood adalah A dan consequences 4, sehingga risiko bernilai extreme. Selain itu, risiko extreme juga terdapat pada pressure transmitter outlet superheater, dengan likelihood B dan consequences 4. Untuk menurunkan risiko, maka dilakukan perawatan dan kalibrasi secara rutin, serta penambahan redundant transmitter. Bahaya paling besar pada seluruh node adalah adanya kebakaran. Oleh karena itu, dilakukan analisis emergency response plan untuk kebakaran yang mencakup peta evakuasi, tugas dan tanggungjawab tiap personel, langkah pencegahan, serta langkah penanganan.

  14. A Comparative biochemical study on two marine endophytes, Bacterium SRCnm and Bacillus sp. JS, Isolated from red sea algae.

    Science.gov (United States)

    Ahmed, Eman Fadl; Hassan, Hossam Mokhtar; Rateb, Mostafa Ezzat; Abdel-Wahab, Noha; Sameer, Somayah; Aly Taie, Hanan Anwar; Abdel-Hameed, Mohammed Sayed; Hammouda, Ola

    2016-01-01

    Two marine endophytic bacteria were isolated from the Red Sea algae; a red alga; Acanthophora dendroides and the brown alga Sargassum sabrepandum. The isolates were identified based on their 16SrRNA sequences as Bacterium SRCnm and Bacillus sp. JS. The objective of this study was to investigate the potential anti-microbial and antioxidant activities of the extracts of the isolated bacteria grown in different nutrient conditions. Compared to amoxicillin (25μg/disk) and erythromycin (15μg/disk), the extracts of Bacterium SRCn min media II, III, IV and V were potent inhibitors of the gram-positive bacterium Sarcina maxima even at low concentrations. Also, the multidrug resistant Staphylococcus aureus(MRSA) was more sensitive to the metabolites produced in medium (II) of the same endophyte than erythromycin (15μg/disk). A moderate activity of the Bacillus sp. JS extracts of media I and II was obtained against the same pathogen. The total compounds (500ug/ml) of both isolated endophytes showed moderate antioxidant activities (48.9% and 46.1%, respectively). LC/MS analysis of the bacterial extracts was carried out to investigate the likely natural products produced. Cyclo(D-cis-Hyp-L-Leu), dihydrosphingosine and 2-Amino-1,3-hexadecanediol were identified in the fermentation medium of Bacterium SRCnm, whereas cyclo (D-Pro-L-Tyr) and cyclo (L-Leu-L-Pro) were the suggested compounds of Bacillus sp. JS.

  15. Un approccio innovativo per l’analisi quantitativa delle superfici di frattura a fatica nelle ghise sferoidali mediante elaborazione di immagini

    Directory of Open Access Journals (Sweden)

    O. Di Bartolomeo

    2008-07-01

    Full Text Available Le osservazioni al microscopio elettronico a scansione (SEM delle superfici di frattura ottenute a seguito di rotture per fatica consentono di evidenziare alcuni meccanismi di avanzamento che dipendono dal materiale e dalla modalità di applicazione delle sollecitazioni. L’introduzione di moderne tecniche di analisi di immagine assistite al calcolatore permette di elaborare un numero di informazioni elevato che consente di porre in relazione le caratteristiche morfologiche locali con il comportamento meccanico macroscopico del materiale.In questo lavoro è stata implementata una tecnica innovativa di analisi di immagine basata sull’analisi della tessitura, valutando l’influenza delle condizioni di applicazione della sollecitazione (ΔK applicato sulla evoluzione del clivaggio rilevato sulle superfici di frattura a fatica di una ghisa sferoidale ferrito-perlitica.

  16. Analisis Rugi Daya Pada Penyulang Bangli Dengan Beroperasinya PLTS Kayubihi

    Directory of Open Access Journals (Sweden)

    I GN Dion Adiputra

    2015-06-01

    Full Text Available Analisis rugi daya pada Penyulang Bangli dilakukan untuk mengetahui perbanding an rugi daya pada jaringan distribusi setelah penempatan pembangkit tersebar jenis PLTS berkapasitas 1 MWp. Lokasi penempatan PLTS ditentukan berdasarkan analisis sensitivitas bus. Nilai sensitivitas bus(?didapat dengan cara membandingkan nilai rugi daya pada sistem dengan total beban yang terhubung pada bus. Penelitian ini menggunakan simulasi aliran daya dengan metode aliran daya Newton-Raphson. Hasil penelitian menunjukkan bus TK 0041 memiliki sensitivitas terbesar dengan nilai ?= 0,178. Dari hasil simulasi aliran daya, penempatan PLTS 1MWp pada lokasi alternatif 1 menghasilkan rugi daya minimum pada Penyulang Bangli yaitu 103,1 kW atau 3,3% dari total suplai daya 3071 kW. Pemasangan PLTS dapat menurunkan rugi daya pada Penyulang Bangli sebesar 57 kW dari total rugi daya pada kondisi tanpa PLTS yaitu 160,1 kW. Bila dibandingkan dengan kondisi eksisting, penem patan PLTS pada lokasi alternatif 1 memiliki selisih rugi daya 7,3 kW lebih kecil dari total rugi daya yang dihasilkan kondisi eksisting sebesar 110,4kW.

  17. ANALISIS TINGKAT KAPABILITAS SISTEM INFORMASI RUMAH SAKIT BERDASARKAN COBIT 5 (MEA01 PADA RSUD TUGUREJO SEMARANG

    Directory of Open Access Journals (Sweden)

    Ariel Bagus Nugroho

    2015-11-01

    Full Text Available RSUD Tugurejo Semarang merupakan Rumah Sakit kelas B milik pemerintah Provinsi Jawa Tengah yang menyediakan pelayanan jasa untuk masyarakat. Dalam manajemen pengolahan data, RSUD Tugurejo Semarang telah menggunakan sistem informasi rumah sakit. Untuk mengetahui apakah sistem informasi telah berjalan seperti yang diharapkan, maka perlu dilakukan analisis tatakelola teknologi informasi. Pada penelitian ini analisis tatakelola teknologi informasi berfokus pada proses pengawasan, evaluasi dan penilaian kinerja, dan kesesuaian kinerja teknologi informasi, yaitu domain MEA01 pada framework COBIT 5.Tujuan penelitian ini untuk mengetahui tingkat kapabilitas dan strategi perbaikan untuk proses pengawasan, evaluasi dan penilaian kinerja dan kesesuaian TI. Metode pengumpulan  data penelitian ini dengan menggunakan studi dokumen, kuesioner dan wawancara kemudian dianalisis tingkat kapabilitas dan kesenjangan. Tingkat kapabilitas yang didapat dari hasil penelitian yaitu berada level 2 (managed. Untuk menaikkan tingkat kapabilitas pada level 3 maka maka perlu dilakukan secara bertahap strategi perbaikan pada PA 2.1, PA2.2, PA 3.1, dan 3.2. Kata kunci: Analisis Tata Kelola TI, COBIT 5, MEA01, Tingkat Kapabilitas, Rumah Sakit.

  18. KONDISI CURAH HUJAN PADA KEJADIAN BANJIR JAKARTA DAN ANALISIS KONDISI UDARA ATAS WILAYAH JAKARTA BULAN JANUARI – FEBRUARI 2013

    OpenAIRE

    Syaifullah, M. Djazim

    2018-01-01

    IntisariKondisi curah hujan di wilayah Jakarta pada kejadian banjir besar tanggal 17 Januari 2013 telah dianalisis yang dihubungkan dengan kondisi atmosfer pada selang waktu tersebut. Data curah hujan menggunakan data TRMM sedangkan analisis kondisi atmosfer menggunakan data rawinsonde. Hasil analisis menunjukkan bahwa puncak kejadian banjir Jakarta musim hujan tahun 2013 terjadi pada tanggal 17 Januari 2013 disebabkan oleh faktor lokal yang sangat kuat ditambah dengan faktor global yang mend...

  19. Analisis Sikap Konsumen terhadap Produk Fashion Lokal dan Impor

    OpenAIRE

    Setiawan, Evelyn

    2014-01-01

    Abstrak: Analisis Sikap Konsumen Terhadap Produk Fashion Lokal dan Impor. Penelitian ini bertujuan untuk menganalisis sikap konsumen terhadap produk fashion lokal dan impor yang akan berpengaruh terhadap keputusan konsumsi. Sampel yang akan digunakan dalam penelitian ini adalah 1.000 mahasiswa dari 10 perguruan tinggi swasta terbesar di Surabaya. Pengambilan data dilakukan dengan metode kuesioner. Hasil pengujian statistik menunjukkan bahwa sebagian besar mahasiswa di Surabaya merasa bangga d...

  20. Uso de Analisis de Covarianza (ANCOVA en investigacion cientifica.

    Directory of Open Access Journals (Sweden)

    Badii, M.H.

    2008-01-01

    Full Text Available The basics of the ANalisis of COVAriance (ANCOVA are given. The objectives and the application of ANCOVA are laid out. Techniques for the estimation of contrasts and for the control and reduction of the degree of error are discussed. The application of a simple ANCOVA using real data is highlighted. The application of this technique in fixing the auxiliary variable in experimentation is emphasized.

  1. Potential use of nuclear irradiation technology for the microbial industry in Malaysia

    International Nuclear Information System (INIS)

    Raja, P.; Isyanti, I.

    2002-01-01

    The potential application of irradiation is numerous. The process seems technically feasible for sterilization of medical devices, pharmaceutical products, foods, cosmetics, packaging materials, scientific laboratory materials like petri dishes, growth media, complying with phytosanitary requirements for fruit and vegetables etc. An awareness of biofertilizer or microbial product has established itself to be a significant part of food production and consumption internationally as well as in Malaysia. People are discovering organic agriculture can serve their need for safe quality food, environment conservation and social accountability. One of the major technical constraints of viable microbial or biofertilizer product production is contaminated free carrier materials. In order to develop the good microbial product, we are practicing the gamma irradiation on our carrier materials and successfully established the product. The different carrier materials were packed and used 25 kGy Cobalt-60 source (JS 8900, SINAGAMA, MINT) for sterilization and simultaneously the materials were sterilized in steam. The cultured Trichoderma virile and T harzianum were mixed with sterilized carrier and observed the colony formin. unit (CFU) on regular intervals. The results showed the efficient colony forming unit on both sterilization method of materials. However, the nuclear irradiation is more cost effective and time saving than steam method. (Author)

  2. ANALISIS RELEVANSI LULUSAN PERGURUAN TINGGI DENGAN DUNIA KERJA

    Directory of Open Access Journals (Sweden)

    Ali Muhson

    2012-04-01

    Full Text Available Abstract: A Relevance Analysis of University Graduates with World of Work. Education should be oriented to the competencies required by the workforce as a percentage of unemployment among the educated increase continuously. This study aims to examine the relevance of YSU Economic Education graduates. The study only focuses on the type of work and subjects taught. The subject of this study is the alumni of Economic Education Study Program. Sampling technique used is snowball sampling. Data collection technique using questionnaires and documentation while the technique of data analysis using descriptive analysis. The result suggests that the majority of the graduates find their first job as private a teacher, a private employee and a tutor, while current job of the most graduates are private teacher, private employee, and civil servant (teacher. The data shows that more than 50 percent of the graduates work in the education area. This implies that the relevance level based on the type of work is categorized as sufficient. Majority of the graduates teaches social science, economic, and entrepreneurship, hence it can be concluded that the relevance level based on the subjects taught is highly relevant.   Keyword: relevance of graduates, type of work, unemployment, employment     Abstrak: Analisis Relevansi Lulusan Perguruan Tinggi dengan Dunia Kerja. Pendidikan harus berorientasi pada kompetensi yang dibutuhkan oleh dunia kerja karena persentase penganggur di kalangan terdidik terus meningkat. Penelitian ini bertujuan untuk mengkaji tingkat relevansi (kesesuaian lulusan Pendidikan Ekonomi UNY. Kajian hanya diarahkan pada jenis pekerjaan dan mata pelajaran yang diampu. Penelitian ini mengambil subjek alumni Prodi Pendidikan Ekonomi dari berbagai angkatan. Teknik sampling yang digunakan adalah snowball sampling. Teknik pengumpulan data menggunakan angket dan dokumentasi sedangkan teknik analisis data menggunakan analisis deskriptif. Penelitian ini

  3. ANALISIS KONTRIBUSI PAJAK HOTEL TERHADAP PENDAPATAN ASLI DAERAH KABUPATEN NUNUKAN

    OpenAIRE

    -, MULIATI

    2014-01-01

    2014 Analisis Kontribusi Pajak Hotel terhadap Pendapatan Asli Daerah Kabupaten Nunukan Analysis of The Contributions Tax on Hotel Againts Regional Renenue Nunukan District Muliati Haerial M. Christian Mangiwa Penelitian ini bertujuan untuk mengetahui seberapa besar kontribusi pajak hotel terhadap pendapatan asli daerah, mengetahui sistem pengawasan, dan potensi yang ada untuk meningkatkan pajak hotel, mengetahui sistem dan prosedur...

  4. Influence of ionizing irradiation on the antioxidant enzymes of Vicia faba L.

    Directory of Open Access Journals (Sweden)

    El-Beltagi, Hossam E. S.

    2010-09-01

    Full Text Available The seeds of Vicia faba L. Giza 834 were exposed to γ-irradiation at dose levels of 2.5, 5.0, 10.0 and 20.0 kGy and after that exposed to He–Ne (632.8 nm or diode (650.0 nm laser irradiation for 5 min. The activities of POD, APOX, CAT, SOD and GST enzymes were significantly stimulated and this stimulation reached its maximum at a dose level of 5.0 kGy for enzymes POD, APOX, CAT and SOD, but for GST enzyme at a dose level 10.0 kGy. For He- Ne laser, with or without different doses (2.5, 5.0, 10.0 and 20.0 kGy of γ-irradiation, enzyme induction was significantly stimulated and positively correlated with the dose levels of γ-irradiation in combination with the He-Ne treatment. There was a significant increase in the concentration of MDA and this increase was more pronounced at dose level 20.0 kGy (38.2 μmol/g d.w compared to the control (3.9 μmol/g d.w. Laser treatment by He–Ne laser or diode laser only caused a slight increase (P 2O2 content significantly increased in all treatments and this increase reached its maximum at dose level 20.0 kGy (36.3 μmol/g d.w compared to the control (2.3 μmol/g d.w.. On the other hand, He-Ne or diode laser treatments combined with γ-irradiation significantly decreased in comparison with γ-irradiation treatments alone. In the case of glutathione content, there were significant increases by γ-irradiation at dose levels 2.5, 5.0, 10.0 and 20.0 kGy. Furthermore, with a combination of γ-irradiation and He-Ne or diode laser, a marked increase in glutathione content was found and was more pronounced than that of gamma irradiation alone.Semillas de Vicia faba L. Giza 834 fueron expuestas a γ-irradiación a dosis de 2.5, 5.0, 10.0 y 20.0 kGy y después expuesta a una radiación laser de He–Ne (632.8 nm o de diodo (650.0 nm durante 5 minutos. Las actividades de las enzimas POD, APOX, CAT, SOD y GST fueron favorecidas significativamente, y éstas alcanzaron un máximo a una dosis de 5.0 kGy para las enzimas

  5. Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo.

    Science.gov (United States)

    Shami, Paul J; Saavedra, Joseph E; Bonifant, Challice L; Chu, Jingxi; Udupi, Vidya; Malaviya, Swati; Carr, Brian I; Kar, Siddhartha; Wang, Meifeng; Jia, Lee; Ji, Xinhua; Keefer, Larry K

    2006-07-13

    The literature provides evidence that metabolic nitric oxide (NO) release mediates the cytotoxic activities (against human leukemia and prostate cancer xenografts in mice) of JS-K, a compound of structure R(2)N-N(O)=NO-Ar for which R(2)N is 4-(ethoxycarbonyl)piperazin-1-yl and Ar is 2,4-dinitrophenyl. Here we present comparative data on the potencies of JS-K and 41 other O(2)-arylated diazeniumdiolates as inhibitors of HL-60 human leukemia cell proliferation, as well as in the NCI 51-cell-line screen for six of them. The data show JS-K to be the most potent of the 42 in both screens and suggest that other features of its structure and metabolism besides NO release may contribute importantly to its activity. Results with control compounds implicate JS-K's arylating ability, and the surprisingly low IC(50) value of the N-(ethoxycarbonyl)piperazine byproduct of NO release suggests a role for the R(2)N moiety. In addition to the above-mentioned in vivo activities, JS-K is shown here to be carcinostatic in a rat liver cancer model.

  6. ANALISIS POTENSI DAN PROYEKSI PENERIMAAN RETRIBUSI PELAYANAN PASAR DI KABUPATEN SEMARANG

    Directory of Open Access Journals (Sweden)

    Evi Fatmawati

    2017-06-01

    Full Text Available Retribusi pelayanan pasar merupakan jenis retribusi jasa umum yang cukup potensial, dikarenakan Kabupaten Semarang menarik retribusi dari 33 pasar tradisional setiap harinya. Tujuan penelitian ini, untuk menganalisis potensi penerimaan retribusi pasar di Kabupaten Semarang tahun 2011 – 2015, serta memproyeksi pendapatan retribusi pelayanan pasar tahun 2016 – 2020. Penelitian ini menggunakan analisis kontribusi, analisis pertumbuhan, analisis potensi, dan analisis ARIMA (2,1,2 (Auto Regressive Integrated Moving Average. Hasil penelitian menunjukan: (1 kontribusi retribusi pelayanan pasar terhadap retribusi daerah dan PAD dalam kategori kurang dan sangat kurang, (2 pertumbuhan retribusi pelayanan pasar berfluktuasi, (3 penerimaan retribusi pelayanan pasar belum berdasarkan potensi, (4 target retribusi pelayanan pasar berada dibawah potensi, (5 proyeksi pendapatan retribusi pasar meningkat dalam lima tahun kedepan. Adanya selisih antara potensi dengan realisasi dapat dijadikan peluang oleh Pemerintah Daerah dalam memaksimalkan penerimaan retribusi pelayanan pasar. Saran peneliti yaitu penetapan target sesuai dengan potensi, serta peningkatan kualitas pelayanan pasar, hal tersebut diharapkan dapat meningkatkan sumbangan retribusi pelayanan pasar terhadap PAD di Kabupaten Semarang. Retribution as a source of local income had a great opportunity to be improve and be develop so. Market retribution service was a kind of public service retribution that potential enough, due to Semarang Regency managed and attracted the retribution of 33 traditional markets every day. The objective of this research was to analyze the potential and contribution of market retribution at Semarang Regency in 2011-2015, also approximate local market retribution service in 2016-2010. This research used contribution analysis, the growth analysis, potential analysis, and analyzed ARIMA (2,1,2 (Auto Regressive Integrated Moving Average. The results of this research that : (1

  7. Characterization and disposal of ion exchange resins used in nuclear installations

    International Nuclear Information System (INIS)

    Flores E, R.M.; Ortiz O, H.B.; Olguin G, M.T.; Emeterio H, M.; Garcia M, H.

    2006-01-01

    To dispose of an appropriate way the used ion exchange resins so much in the pool water purification systems of the TRIGA Mark III reactor like in the JS6500 gamma irradiator, of the National Institute of Nuclear Research, were carried out a series of analytic nuclear techniques and complementary conventional to those recommended by the ASTM, with the object of to control and to manage 14 lots of worn out resins appropriately. For its were identified the radioactive isotopes, the resins type, the grade of chemical pollution and the physicochemical degradation of the same ones. The lots of resins that didn't contain radioactive isotopes its were regenerated in an usual way, as long as those that if they controlled them they selected options for its final disposition. The first selected option was the extraction method of ion radioactive isotopes, concentrating the elution product by evaporation. As second option it was carried out the resins stabilization damaged by micro-encapsulation by forged to ambient temperature, using an organic polymer. Previous to the immobilization the resins were pretreated by vacuum drying, pulverization and thermal drying, however before carrying out this last, it was carried out a thermal gravimetric analysis to determine the drying conditions of the resins avoiding its chemical decomposition. (Author)

  8. Characterization and disposal of ion exchange resins used in nuclear installations; Caracterizacion y disposicion de resinas de intercambio ionico utilizadas en instalaciones nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Flores E, R.M.; Ortiz O, H.B.; Olguin G, M.T.; Emeterio H, M.; Garcia M, H. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

    2006-07-01

    To dispose of an appropriate way the used ion exchange resins so much in the pool water purification systems of the TRIGA Mark III reactor like in the JS6500 gamma irradiator, of the National Institute of Nuclear Research, were carried out a series of analytic nuclear techniques and complementary conventional to those recommended by the ASTM, with the object of to control and to manage 14 lots of worn out resins appropriately. For its were identified the radioactive isotopes, the resins type, the grade of chemical pollution and the physicochemical degradation of the same ones. The lots of resins that didn't contain radioactive isotopes its were regenerated in an usual way, as long as those that if they controlled them they selected options for its final disposition. The first selected option was the extraction method of ion radioactive isotopes, concentrating the elution product by evaporation. As second option it was carried out the resins stabilization damaged by micro-encapsulation by forged to ambient temperature, using an organic polymer. Previous to the immobilization the resins were pretreated by vacuum drying, pulverization and thermal drying, however before carrying out this last, it was carried out a thermal gravimetric analysis to determine the drying conditions of the resins avoiding its chemical decomposition. (Author)

  9. ANALISIS FINANSIAL DAN KELEMBAGAAN RANTAI NILAI MEBEL MAHONI JEPARA

    Directory of Open Access Journals (Sweden)

    Nunung Parlinah

    2011-12-01

    Full Text Available Industri mebel umumnya termasuk dalam industri kecil dan menengah. Selain berperan dalam penerimaan devisa, bisnis di bidang mebel ini juga menciptakan lapangan kerja bagi masyarakat terutama di Kabupaten Jepara. Adanya hubungan (pemberi kepercayaan - (penerima kepercayaan yang terjadi antar aktor atau pelaku di dalam rantai berpengaruh terhadap besarnya distribusi nilai tambah yang diperoleh oleh masingmasing pelaku di sepanjang rantai nilai Tujuan dari penelitian ini adalah mengidentifikasi kelembagaan (aturan yang terjadi antar pelaku di sepanjang rantai nilai mebel mahoni Jepara dan menentukan skenario kebijakan yang dapat mendukung bagi kelestarian industri mebel Jepara. Data yang digunakan meliputi data primer dan data sekunder. Analisis data meliputi identifikasi aktor dan kelembagaan (aturan yang terjadi antar pelaku serta analisis manfaat biaya yang terdiri dari NVP, BCR dan IRR. Hasil penelitian menunjukkan bahwa (1 para pengrajin ( memproduksi mebelnya lebih didasarkan pada pesanan pembeli ( . agent principal Asymetic information yang terjadi antara pedagang kayu dan petani juga telah mengakibatkan posisi petani sebagai (2 Nilai NPV, BCRdan IRR untuk tiap pelaku berbeda-beda tetapi nilai-nilai tersebut mengindikasikan bahwa pola kemitraan yang terjadi antar pelaku dalam rantai nilai mebel mahoni saat ini sudah efektif. Skenario kebijakan yang dapat diterapkan adalah kebijakan yang bersifat insentif bagi petani hutan rakyat, peningkatan kemampuan pengrajin di bidang pemasaran; dan membangun aksi kolektif diantara pengrajin. price taker;

  10. Spectral signature of ultraviolet solar irradiance in Zacatecas

    Energy Technology Data Exchange (ETDEWEB)

    Pinedo V, J. L; Mireles G, F; Rios M, C; Quirino T, L. L; Davila R, J. I [Universidad Autonoma de Zacatecas, Zacatecas, Zacatecas (Mexico)

    2006-10-15

    This study presents an analysis of the global ultraviolet spectral irradiance (290-400 nm) registered in Zacatecas, a city near the Tropic of Cancer, located at 2500 m above sea level, latitude of 22 degrees N and longitude of 102 degrees W. The spectra have been measured using a Bentham radiometer with a 0.5 nm step in wavelength. The measurements show relatively high levels of ultraviolet irradiance (UV), which may be characteristic of areas close to the Tropic of Cancer. Faced with an increase of the incidence of skin cancer among the population of Zacatecas, these measurements highlight that a damage prevention plan is required. [Spanish] En este trabajo se presenta un analisis de la radiacion espectral global ultravioleta (290-400 nm) registrada en Zacatecas, una ciudad vecina al tropico de cancer, situada a 2500 m sobre el nivel del mar, latitud de 22 grados N y longitud de 102 grados O. Los espectros correspondientes han sido medidos mediante un espectroradiometro Bentham con un paso de 0.5 nm de longitud de onda. Las mediciones muestran niveles de radiacion ultravioleta (UV) relativamente elevados, que pueden ser caracteristicos de las zonas vecinas al tropico de cancer. Frente al aumento de incidencia de cancer en la piel en la poblacion del estado de Zacatecas, estas mediciones ponen en relieve la necesidad de formular un plan preventivo de danos.

  11. Inspection of the coupling part material degradation. Some experiences and results from SKODA JS related to internals

    International Nuclear Information System (INIS)

    Brynda, J.

    1998-01-01

    In this presentation some experiences and results from SKODA JS, related to internals, are reported. Sketches of the construction of WWER 440 RPV and internal's materials, including chemical composition are given. The results of hardness tests on internal parts are reported as well as some changes in the construction of internal parts which were made to improve their crack and fracture properties

  12. ANALISIS SKENARIO KEGAGALAN SISTEM UNTUK MENENTUKAN PROBABILITAS KECELAKAAN PARAH AP1000

    Directory of Open Access Journals (Sweden)

    D.T. Sony Tjahyani

    2014-03-01

    Full Text Available Kejadian Fukushima telah menunjukkan bahwa kecelakaan parah dapat terjadi, maka dari itu sangatlah penting untuk menganalisis tingkat keselamatan pada reaktor daya. Berdasarkan rekomendasi expert mission IAEA setelah kejadian Fukushima, perlu dilakukan upaya untuk meminimalisasi terjadinya kecelakaan parah yaitu dengan melakukan proses pendinginan yang maksimal. Dalam konsep keselamatan fasilitas nuklir, khususnya reaktor daya telah diterapkan konsep keselamatan berlapis (Defence in Depth, DiD. Konsep keselamatan tersebut terdiri atas 5 level pertahanan yang bertujuan mencegah dan mengurangi lepasan produk fisi ke masyarakat dan lingkungan pada saat reaktor daya mengalami kecelakaan. Dalam reaktor telah didesain sistem atau tindakan yang mempunyai fungsi untuk mengatasi setiap level tersebut. Tujuan dari analisis ini adalah menentukan probabilitas kecelakaan parah dengan melakukan skenario kegagalan sistem dalam proses pendinginan di reaktor. Sebagai obyek analisis adalah reaktor daya AP1000, karena jenis reaktor ini sedang banyak dibangun saat ini. Skenario dilakukan dengan mengasumsikan beberapa kombinasi kegagalan sistem yang termasuk dalam DiD level 2 dan 3. Kegagalan sistem kemudian dianalisis dengan menggunakan analisis pohon kegagalan berdasarkan perangkat lunak SAPHIRE ver. 6.76. Dari analisis didapatkan probabilitas gagal dari kelompok sistem DiD level 2 dan 3 pada AP1000 masih di bawah batas kriteria dari IAEA yaitu lebih kecil dari 10-2, serta probabilitas kecelakaan parah didapatkan sebesar 6,17 x 10-10. Berdasarkan analisis ini disimpulkan bahwa AP1000 mempunyai tingkat keselamatan yang cukup tinggi, karena melalui skenario kegagalan sistem didapatkan probabilitas kecelakaan parah yang sangat kecil.   ABSTRACT Fukushima accident has shown that severe accident could be occurred, therefore it is important to analyze safety level of nuclear power plants. Based on the recommendations of IAEA expert mission after the Fukushima accident

  13. Neuroprotective Compound from an Endophytic Fungus, Colletotrichum sp. JS-0367.

    Science.gov (United States)

    Song, Ji Hoon; Lee, Changyeol; Lee, Dahae; Kim, Soonok; Bang, Sunghee; Shin, Myoung-Sook; Lee, Jun; Kang, Ki Sung; Shim, Sang Hee

    2018-05-23

    Colletotrichum sp. JS-0367 was isolated from Morus alba (mulberry), identified, and cultured on a large scale for chemical investigation. One new anthraquinone (1) and three known anthraquinones (2-4) were isolated and identified using spectroscopic methods including 1D/2D-NMR and HRESIMS. Although the neuroprotective effects of some anthraquinones have been reported, the biological activities of the four anthraquinones isolated in this study have not been reported. Therefore, the neuroprotective effects of these compounds were determined against murine hippocampal HT22 cell death induced by glutamate. Compound 4, evariquinone, showed strong protective effects against HT22 cell death induced by glutamate by the inhibition of intracellular ROS accumulation and Ca 2+ influx triggered by glutamate. Immunoblot analysis revealed that compound 4 reduced the phosphorylation of MAPKs (JNK, ERK1/2, and p38) induced by glutamate. Furthermore, compound 4 strongly attenuated glutamate-mediated apoptotic cell death.

  14. Mobilā lietotne: "Instagram bilžu plānotājs"

    OpenAIRE

    Cibuļskis, Aigars

    2016-01-01

    Šajā dokumentā ir iekļauta Latvijas Universitātes Datorikas fakultātes kursa “Kvalifikācijas darbs II” (DatZ2049) praktiskā darba ietvaros izstrādātā lietotne “Mobila lietotne “Instagram bilžu plānotājs”” tehniskā dokumentācija, kas ietver programmatūras prasību specifikāciju, datu bāzes un ekrānformu projektējumus. Instagram bilžu plānotājs - ir lietotne Android platformai, kura domāta atvieglot bilžu izlikšanu sociālajā tīklā Instagram, modes blogeriem un mā...

  15. Analisis Neraca Air Lahan untuk Tanaman Padi dan Jagung Di Kota Bengkulu

    Directory of Open Access Journals (Sweden)

    Jaka A. I. Paski

    2018-01-01

    Citation: Paski, J.A.I., Faski, G.I.S.L., Handoyo, M.F. dan Pertiwi, D.A.S. (2017. Analisis Neraca Air Lahan untuk Tanaman Padi dan Jagung di Kota Bengkulu. Jurnal Ilmu Lingkungan, 15(2, 83-89, doi:10.14710/jil.15.2.83-89

  16. Pengaruh Advance Organizer Berbasis Proyek Terhadap Kemampuan Analisis – Sintesis Siswa

    Directory of Open Access Journals (Sweden)

    Tasiwan -

    2014-01-01

    Full Text Available Penelitian ini dilakukan untuk mengetahui pengaruh model pengatur kemajuan (advance organizer berbasis proyek terhadap kemampuan analisis – sintesis siswa pada konsep Energi. Sebelum pembelajaran, diberikan tugas proyek pada siswa untuk merealisasikan bel listrik sederhana, rangkaian arus seri - paralel, dan tuas. Produk proyek digunakan sebagai advance organizer dalam pembelajaran di kelas. Penguatan kognitif dilakukan melalui diskusi kelompok dan pembuatan peta konsep, ekspositori guru di kelas, dan kegiatan eksperimen laboratorium. Data diambil melalui pretest, post test, observasi partisipatif pembelajaran oleh dua orang observer, penilaian produk, peta konsep dan laporan kegiatan eksperimen. Teknik analisis data meliputi uji prasyarat data dan uji hipotesis Hasil penelitian menunjukkan bahwa siswa mengalami peningkatan kemampuan analisis – sintesis dalam aspek menguraikan, mengkategorikan, mengidentifikasi, merumuskan pernyataan, merekonstruksi, menentukan konsep, dan menganalisis konsep dengan rata – rata peningkatan delta skor sebesar 54,46 %, uji t sebesar 6,4, dan skala gain sebesar 0,3. This study was conducted to determine the effect of project-based advance organizer model on student’s analysis - synthesis ability of the energy concept. Students were given an assignment to realize the project on simple electric bell, the series – parallel circuit, and lever, before learning. The products of project were used as an advanced organizer in the learning activity. Cognitive strengthening was done through group discussions and concept mapping, expository learning in the classroom, and laboratory experiments activities. The data were taken through a pretest, post-test, participant observation study by two observers, product assessment, concept maps and report of experiment activities. Results showed that the students’ analysis - synthesis ability increased in the aspect of describing, categorizing, identifying, statement

  17. ANALISIS BEBAN KERJA DENGAN MENGGUNAKAN METODE CVL DAN NASATLX DI PT. ABC

    Directory of Open Access Journals (Sweden)

    Renty Anugerah Mahaji Puteri

    2017-10-01

    Full Text Available PT. ABC merupakan perusahaan Jepang yang bergerak di bidang usaha jasa konstruksi mekanikal, elektrikal, dan system komunikasi. Sebagai perusahaan jasa konstruksi, PT. ABC dituntut untuk mencapai tujuan / target perusahaan tiap tahunnya yaitu mendapatkan tender proyek, maka tak jarang karyawannya dituntut untuk lembur. Seringnya karyawan lembur, maka menimbulkan masalah kelelahan terhadap para karyawannya sehingga target tidak tercapai. Penelitian ini bertujuan untuk mengevaluasi beban kerja yang dialami oleh engineer leader pada Departemen DesaindanOperasional di PT. ABC. Beban kerja yang diukur adalah beban kerja fisik dan mental. Beban kerja fisik diukur berdasarkan cardiovascular load (CVL. Beban kerja mental diukur dengan menggunakan metode NASA-Task Load Index (NASA-TLX. Berdasarkan hasil analisis CVL, beban kerja fisik yang diterima engineer proyek memiliki presentase CVL sebesar 31,16%, denganhasilperbaikanmenjadi 23,38%. Sedangkan dari hasil analisis NASA-TLX, beban kerja mental yang diterima engineer proyek yaitu dengan skor NASA-TLX 74,2% denganhasilperbaikanmenjadi 51,6%, sedangkan skor NASA-TLX engineer head office 61,5% denganhasilperbaikanmenjadi 47,66%.

  18. Analisis Struktur Kristal Lifepo4 Olivine Sebagai Bahan Katoda Batere Li-Ion

    Directory of Open Access Journals (Sweden)

    Indra Gunawan

    2013-10-01

    Full Text Available Sintesis LiFePO4 dilakukan dengan pencampuran LiCl, FeCl2.4H2O dan H3PO4 ekuimolar ke dalam air. Homogenasi larutan dilakukan dengan pengaduk magnetic pada suhu 60o C. Prekursor LiFePO4 diperoleh setelah pemanasan 200o C dengan furnace selama 2 jam. Sintering prekursor LiFePO4 dilakukan pada suhu 700o C dengan furnace selama 4 jam dengan aliran N2 untuk membentuk fasa kristalit LiFePO4. Kemurnian fasa dan struktur kristal dianalisis dengan menggunakan XRD. Analisis struktur kristal dari pola difraksi sinar-X dilakukan dengan perangkat lunak FULLPROF. Pengamatan morfologinya dilakukan dengan menggunakan SEM dengan kombinasi energy dispersive spectroscopy (EDS dan pengukuran gugus fungsional dengan FT-IR. Hasil analisis struktur kristal menunjukkan bahwa senyawa LiFePO4 memiliki struktur Kristal orthorhombic, space group 62, simbol Pnma (Hermann-Mauguin dengan parameter kisi a= 6.0019999, b= 10.330000, c= 4.6999998. 

  19. Analisis dan Rencana Pengembangan Jaringan Distribusi Air Bersih Unit Cabang Timur PDAM Kabupaten Klaten

    Directory of Open Access Journals (Sweden)

    Ana Tri Lestari

    2017-01-01

    Full Text Available Unit Cabang Timur Perusahaan Daerah Air Minum (PDAM Kabupaten Klaten dibagi menjadi 3 unit pelayanan Ibu Kota Kecamatan (IKK dan mempunyai tingkat pelayanan yang masih rendah pada tahun 2015, yaitu Unit IKK Ceper 17,6%; Unit IKK Pedan 2,43%; dan Unit IKK Cawas 31,26% sehingga peningkatan persen pelayanan menjadi hal yang perlu dilakukan. Hal ini didukung dengan adanya penambahan debit produksi sebesar 50 liter/detik. Selain itu, jaringan distibusi belum dibentuk blok pelayanan sehingga sulit untuk mengontrol kehilangan air. Perencanaan ini dilakukan pembagian blok pelayanan menjadi 26 blok dan 5 tapping. Setelah itu dilakukan analisis kondisi eksiting. Hasil analisis kondisi eksisting menunjukkan kondisi hidrolika perpipaan kecuali kecepatan masih memenuhi kriteria, yaitu tekanan antara (15,43-59,99 m, kecepatan (0-0,91 m/detik, unit headloss (0-3,51 m/km. Kemudian dilakukan pengembangan jaringan yang dibagi menjadi 2 tahap, dimana tahap 1 meningkatkan persen pelayanan, sedangkan tahap 2 menambah daerah pelayanan baru. Blok pelayanan setelah pengembangan menjadi 29 blok dan 5 titik tapping. Kemudian analisis rencana pengembangan dilakukan dan menunjukkan bahwa kondisi hidrolika pipa untuk tekanan di jaringan distribusi IKK Cawas bernilai negatif. Hal ini dikarenakan unit headloss yang terjadi pada pipa dari reservoir menuju titik tapping pertama IKK Cawas sebesar 5,78 m/km dengan panjang pipa 14,35 km sehingga headloss  sebesar 82,94 m menyebabkan tekanan menjadi -2,89 m. Permasalahan ini dapat diatasi dengan parallel pipa diameter 200 mm sepanjang 9 km. Parallel pipa tersebut mengakibatkan tekanan  pada titik tapping pertama IKK Cawas menjadi 34,65 m dan titik tapping terjauh (blok 19 sebesar 16,34 m.  Hasil analisis hidrolika, seperti unit headloss berada pada rentang (0-5,78 m/km, namun kecepatan masih ada yang di bawah 0,3 m/detik. Rencana anggaran biaya (RAB yang dibutuhkan untuk melakukan pengembangan jaringan sebesar Rp 2.470.153,051.71.

  20. Analisis Karakteristik Hujan untuk Pendugaan Debit Aliran Rencana Sungai Anafri di Kota Jayapura

    Directory of Open Access Journals (Sweden)

    Nurfaijin Nurfaijin

    2016-10-01

    Full Text Available ABSTRAK Penelitian ini bertujuan mengkaji karakteristik hujan wilayah DAS Anafri, menghitung debit aliran rencana, dan mengkaji kapasitas Sungai Anafri dalam merespon pengalihragaman hujan menjadi aliran permukaan. Kajian karakteristik hujan yakni ketebalan, intensitas, dan durasi hujan dilakukan dengan analisis statistik data hujan. Analisis distribusi data hujan diasumsikan sesuai dengan Metode Gumbel, sehingga untuk menentukan hujan periode ulang 2 tahun, 5 tahun, 10 tahun, dan 25 tahun menggunakan persamaan Gumbel. Hujan periode ulang digunakan untuk menghitung debit aliran rencana Metode Rasional. Analisis kapasitas sungai dilakukan dengan membandingkan debit aliran rencana dalam periode ulang T dengan kapasitas sungai. Penghitungan kapasitas sungai dilakukan pada penampang PI (bagian hulu, P2,dan P3 (bagian hilir. Debit aliran rencana yang digunakan dalam analisis kapasitas sungai adalah debit aliran Q25tahun (107,478 m³/detikdan 163,726 m³/detik. Hasil analisis menunjukan bahawa, terjadinya limpasan pada penampang sungai PI dan P2 pada saat menampung debit banjir yang diketahui penyebab utamanya adalah bank full capacity kecil, maka alternat! ( penanganan yang direkomendasikan adalah peninggian tanggul sungai. Analisis kapasitas sungai menggunakan debit banjir periode ulang 25 tahun menunjukan bahwa, terjadi limpasan pada lokasi penampang PI sampai P2 dengan panjang ruas 400 m yang terjadi pada tanggul sisi kanan dan tanggul sisi kiri dengan panjang ruas 40 meter. Limpasan terjadi setinggi 0,1 m hingga 1,6 m pada tanggul sisi kanan dan 0,1 m hingga 0,3 m pada tanggul sisi kiri, sehingga peninggian tanggul yang direkomendasikan adalah setinggi 1,6 mpada sisi kanan dan 0,3 m pada tanggul sisi kiri. ABSTRACT This study aims to examine the characteristics of rainfall watershed of Anafri calculate the flow rate plan, and assess the river capacity to respond diversion of rain to be surface runoff. In this study, the analysis of rainfall

  1. Market testing and consumer acceptance of irradiated rice (Oryza sativa indica Linn.)

    International Nuclear Information System (INIS)

    Ungsunantwiwat, Ampai; Sophonsa, Sombut

    2001-01-01

    Special grade A fragrant rice (Jasmine rice) of 13% moisture content was obtained from a local miller in Bangkok. Low density polyethylene, 29.5 cm in width x 45 cm in length and 200 micron in thickness, was used to pack the rice with a net weight of 5 kg. The irradiated food label was printed on one side of the bag to comply with food control regulations. The color and the ink for marking were tested for gamma radiation compatibility. A total of 800 bags of rice, with a total gross weight of 4,000 kg, were irradiated at a minimum absorbed dose at 0.5 kGy for insect disinfestation. Radiation treatment was carried out using a multi-purpose, carrier type gamma irradiator (Model JS-8900, Serial No. IR-155) located at the Thai Irradiation Center. Irradiated rice was distributed on a weekly basis to food stores in Bangkok and Pathum Thani, as well as to various governmental organizations and interested individuals. The product was sold at 60 bahts per bag (approx. US$ 2.4) to retailers. Various commercial brands of non-irradiated rice of 5 kg size, were available in the market at 52 to 78 bahts per bag (approx. US $ 2.08 to 3.12), depending on quality and brand name. During the distribution, a leaflet of educational information was given to the consumer. A simple questionnaire used in the marketing trial indicated that 72% of the consumers bought irradiated rice because of the good quality of the product based on visual inspection, and 28% of them were willing to try the new product. Most consumers preferred irradiated rice to chemical treatment (fumigation) for insect disinfestation. However, most consumers were not sure if they would like to buy irradiated rice again unless its cooking quality was acceptable. Market testing of irradiated rice in the upper-class market or supermarket was unsuccessful because of limitations in the sale and service conditions. To meet the requirement of the supermarket retailer, irradiated rice had to be supplied on a monthly basis, with

  2. Analisis “Brand Equity” Siaran Berita Stasiun Televisi Swasta Indonesia

    OpenAIRE

    Arif Sugiono; Prima Mulyasari Agustina

    2004-01-01

    Penelitian ini bertujuan untuk mengetahui keadaan berbagai merek siaran berita stasiun televisi swasta berdasarkan dimensi ekuitas mereknya, dengan memfokuskan pada empat dimensi ekuitas merek, yang meliputi loyalitas merek, kesadaran merek, persepsi kualitas, dan asosiasi merek. Metode yang digunakan metode deskriptif, dengan analisis data menggunakan tabulasi dan teknik skala. Hasil penelitian dari dimensi loyalitas merek tiga besar siaran berita secara berurutan adalah Buser, Patroli dan L...

  3. Analisis Derau dalam Perancangan Rangkaian Terintegrasi Op-Amp

    Directory of Open Access Journals (Sweden)

    Siti Sendari

    2009-02-01

    Full Text Available Perancangan IC Op-Amp, memerlukan spesifikasi-spesifikasi yang meliputi parameter proses dan parameter perancangan. Dalam menentukan parameter perancangan, derau merupakan suatu hal yang tidak bisa ditinggalkan, karena derau dapat menentukan keandalan perancangan. Untuk menganalisis derau pada IC Op-Amp langkah pertama yang harus diketahui adalah sumber-sumber derau, setelah itu dilakukan analisis derau baik secara teoritis maupun secara simulasi untuk mengetahui derau yang mungkin terjadi dalam perancangan IC, apakah sudah sesuai dengan spesifikasi yang ditentukan atau tidak. Untuk simulasi derau dapat dilakukan dengan program Spice.

  4. Pembelajaran Biokimia melalui Analisis Kasus-kasus Olahraga untuk Meningkatkan Sport Scientific Literaci Mahasiswa

    Directory of Open Access Journals (Sweden)

    - Erman

    2013-01-01

    Full Text Available Abstract: Biochemistry Teaching through Sport-case Analyses to Improve Students' Sport Scientific Literacy. This quasi-experimental study focuses on examining the effect of biochemistry teaching on students' sport scientific literacy (SSL. The study involved 107 students of a teacher training institution, selected using a stratified random sampling. The results of t-test utilizing pre-test and post-test control group design show that biochemistry teaching affects students' SSL, as indicated by the scores of the experimental group which were four times higher than those of the control group. The SSL level of the experimental group increased from level 2 (nominal and level 3 (functional to level 3 (functional, level 4 (conceptual, and level 5 (multidimensional. Abstrak: Pembelajaran Biokimia melalui Analisis Kasus-kasus Olahraga untuk Meningkatkan Sport Scientific Literaci Mahasiswa. Penelitian ini bertujuan untuk mengetahui pengaruh pembelajaran biokimia melalui analisis kasus-kasus olahraga terhadap literasi sport scientific mahasiswa. Sebanyak 107 mahasiswa dari program studi ilmu keolahragaan sebuah LPTK di Surabaya dipilih sebagai sampel dengan menggunakan sampling random berstrata. Desain yang digunakan adalah desain pretest-posttest control group dari desain kuasi eksperimen. Data dianalisis dengan uji-t sampel independen. Hasil peneli­tian menunjukkan bahwa pembelajaran biokimia melalui analisis kasus-kasus olahraga merupakan suatu metode yang efektif untuk meningkatkan sport Scientific literacy (SSL mahasiswa. Rerata skor perolehan SSL yang diperoleh mahasiswa kelompok eksperimen sekitar 4 kali lebih tinggi daripada yang diperoleh mahasiswa kelompok kontrol. Tingkatan SSL mahasiswa naik dari level 2 (nominal dan level 3 (fungsional menjadi level 3 (fungsional, level 4 (konseptual, dan level 5 (multidimensional.

  5. Visualization of protein sequence features using JavaScript and SVG with pViz.js.

    Science.gov (United States)

    Mukhyala, Kiran; Masselot, Alexandre

    2014-12-01

    pViz.js is a visualization library for displaying protein sequence features in a Web browser. By simply providing a sequence and the locations of its features, this lightweight, yet versatile, JavaScript library renders an interactive view of the protein features. Interactive exploration of protein sequence features over the Web is a common need in Bioinformatics. Although many Web sites have developed viewers to display these features, their implementations are usually focused on data from a specific source or use case. Some of these viewers can be adapted to fit other use cases but are not designed to be reusable. pViz makes it easy to display features as boxes aligned to a protein sequence with zooming functionality but also includes predefined renderings for secondary structure and post-translational modifications. The library is designed to further customize this view. We demonstrate such applications of pViz using two examples: a proteomic data visualization tool with an embedded viewer for displaying features on protein structure, and a tool to visualize the results of the variant_effect_predictor tool from Ensembl. pViz.js is a JavaScript library, available on github at https://github.com/Genentech/pviz. This site includes examples and functional applications, installation instructions and usage documentation. A Readme file, which explains how to use pViz with examples, is available as Supplementary Material A. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  6. Identifiksi Sebaran Litologi berdasarkan Analisis Data Resistivitas di Gunung Wungkal

    OpenAIRE

    Nurul Dzakiya; MGS. Dwiki Nugraha; Nenden L. Sidik; Trias Galena

    2017-01-01

    Analisis data untuk mengidentifikasi sebaran litologi yang memiliki potensi bahan galian industri di Daerah Gunung Wungkal Yogyakarta dengan menggunakan metode resistivitas dan survei geologi permukaan telah dilakukan. Hasil korelasi kedua data tersebut menunjukkan sebaran litologi merupakan pelapukan intrusi batuan beku yang kemudian menghasilkan material lempung (6,0-10 m), lempung pasiran (11-30 m) dan lapukan batuan diorit (30-55 m) yang berada di kedalaman berbeda. Ketebalan batuan di pe...

  7. Analisis Pemasaran Ayam Ras Pedaging di Pasar Tradisional Kota Medan

    OpenAIRE

    Fachri, Yusrizal

    2017-01-01

    130306044 YUSRIZAL FACHRI, 2017. “Analisis Pemasaran Ayam Ras Pedaging di Pasar Tradisional Kota Medan”. Dibimbing oleh ARMYN HAKIM DAULAY dan NEVY DIANA HANAFI. Penelitian ini bertujuan untuk mengidentifikasi karakteristik lembaga pemasaran, bentuk saluran, fungsi pemasaran, dan menganalisis nilai tambah di lembaga-lembaga pemasaran ayam ras pedaging di pasar tradisional Kota Medan pada April sampai Mei 2017. Penelitian ini menggunakan data primer yang didapatkan dari observasi dan waw...

  8. Analisis Kekuatan Struktur Pallet Menggunakan Metode Elemen Hingga

    Directory of Open Access Journals (Sweden)

    Tria Mariz Arief

    2015-07-01

    Full Text Available Pallet sebagai suatu alat bantu untuk mempermudah proses bongkar-muat logistik. Palletdigunakan hampir dalam berbagai lingkungan transportasi logistik. Pada bahasan berikutdikhususkan dalam lingkup transportasi di dalam pesawat udara khususnya pada pesawatangkut militer. Di lingkungan militer pallet digunakan untuk transport logistik baik secara normalmuat (loading dan bongkar (unloading maupun kondisi bongkar dengan diterjunkan daripesawat udara. Untuk pemenuhan penggunaan tersebut dilakukan perancangan ulang (reverseengineering struktur pallet yang dapat dimanufaktur secara lokal. Hipotesis awal menunjukkanbahwa berdasarkan kondisi pembebanan pada pallet dapat diperkirakan bahwa kondisitegangan dan regangan maksimum akan terjadi pada posisi sudut struktur pallet yang ditransferbebannya ke komponen plat besi penahan siku-siku dan baut. Material yang digunakan padastruktur pallet adalah Allumunium Alloy 7075-T6 dengan kekuatan tarik sebesar 503 MPa.Analisis dilakukan dengan menggunakan simulasi numerik dengan metoda elemen hingga(FEM. Proses simulasi numerik kekuatan struktur pallet difokuskan pada pembebanan statis(termasuk pengaruh factor G dalam interval beban statis 4 ton sampai 7 ton. Analisis dilakukanpada perubahan variabel tegangan dan regangan terhadap variasi beban yang diberikan untukmendapatkan tingkat keamanan struktur (margin safety. Pemodelan dilakukan denganidealisasi model ¼ bagian menggunakan elemen terstruktur dengan jenis elemen hexahedral(brick dengan jumlah 73803 elemen dan 360323 node. Hasil analisis menunjukkan teganganekuivalen maksimum struktur Pallet adalah 94 MPa yang terjadi di penguat sudut (anglebracket. Sedangkan pada struktur penguat lapis (sandwich structure berbahan thick blockyang mempunyai kekuatan sebesar 20 MPa adalah sebesar 0.84 MPa. Tingkat keamanansecara keseluruhan struktur dengan mempertimbangkan factor G hingga 2 adalah 5.3.Kata kunci: Analisis struktur, pallet, logistik, reverse engineering, FEM

  9. Blood group genotyping for Jk(a)/Jk(b), Fy(a)/Fy(b), S/s, K/k, Kp(a)/Kp(b), Js(a)/Js(b), Co(a)/Co(b), and Lu(a)/Lu(b) with microarray beads.

    Science.gov (United States)

    Karpasitou, Katerina; Drago, Francesca; Crespiatico, Loretta; Paccapelo, Cinzia; Truglio, Francesca; Frison, Sara; Scalamogna, Mario; Poli, Francesca

    2008-03-01

    Traditionally, blood group typing has been performed with serologic techniques, the classical method being the hemagglutination test. Serotyping, however, may present important limitations such as scarce availability of rare antisera, typing of recently transfused patients, and those with a positive direct antiglobulin test. Consequently, serologic tests are being complemented with molecular methods. The aim of this study was to develop a low-cost, high-throughput method for large-scale genotyping of red blood cells (RBCs). Single-nucleotide polymorphisms associated with some clinically important blood group antigens, as well as with certain rare blood antigens, were evaluated: Jk(a)/Jk(b), Fy(a)/Fy(b), S/s, K/k, Kp(a)/Kp(b), Js(a)/Js(b), Co(a)/Co(b), and Lu(a)/Lu(b). Polymerase chain reaction (PCR)-amplified targets were detected by direct hybridization to microspheres coupled to allele-specific oligonucleotides. Cutoff values for each genotype were established with phenotyped and/or genotyped samples. The method was validated with a blind panel of 92 blood donor samples. The results were fully concordant with those provided by hemagglutination assays and/or sequence-specific primer (SSP)-PCR. The method was subsequently evaluated with approximately 800 blood donor and patient samples. This study presents a flexible, quick, and economical method for complete genotyping of large donor cohorts for RBC alleles.

  10. Analisis Tata Kelola Teknologi Informasi Menggunakan Kerangka Kerja COBIT 4.1 pada Fakultas Teknik Undip

    Directory of Open Access Journals (Sweden)

    Arini Arumana

    2014-06-01

    Full Text Available Peran teknologi informasi dalam suatu instansi sudah tidak dapat dielakkan lagi, mengingat perkembangannya yang begitu pesat seiring berjalannya waktu. Namun masalah yang sering terjadi di instansi adalah penggunaan teknologi informasi yang kadang tidak sesuai dengan harapan. Oleh karena itu diperlukan tata kelola terhadap penggunaan teknologi informasi yang biasa disebut dengan IT Governance. Fakultas teknik UNDIP adalah salah satu fakultas yang dalam operasionalnya sangat mengandalkan teknologi informasi, baik dalam aktifitas belajar mengajar maupun dalam menjalankan operasional bisnis. Kondisi sekarang di Fakultas Teknik sendiri tidak terdapat suatu indikator yang dapat menyatakan bahwa kinerja TI yang berjalan telah sesuai dengan visi dan misi Fakultas Teknik, oleh karena itu perlu dilakukan analisis tata kelola teknologi informasi, guna mengetahui performa TI sekarang sesuai dengan yang diharapkan oleh managemen atau tidak. Hasil dari analisis ini berupa tingkat kematangan tata kelola TI yang mecerminkan kondisi tata kelola TI di Fakultas Teknik dengan mengacu pada maturity level yang disediakan kerangka kerja COBIT 4.1, yakni dari level 0 (non-existent sampai 5 (optimized. Berdasarkan analisis yang dilakukan, secara garis besar kondisi kematangan tata kelola TI Fakultas Teknik berada pada level 2 yakni repeatable but intuitive. Kondisi ini mengacu pada beberapa kelemahan dalam proses-proses TI yang berjalan, diantaranya penetapan dan dokumentasi tindakan, kebijakan dan prosedur yang minim, serta tidak tersedianya service level yang disetujui bersama.

  11. ANALISIS KEBUTUHAN UNTUK PENGEMBANGAN MODUL INKUIRI BERBASIS PERTANYAAN (MIBP DI SMP

    Directory of Open Access Journals (Sweden)

    Desak Made Citrawathi

    2016-08-01

    Full Text Available melakukan analisis kebutuhan untuk pengembangan dan penyusunan modul inkuri berbasis pertanyaan (MIBP. MIBP disusun untuk memfasilitasi pembelajaran sains agar dapat meningkatkan penguasaan konsep biologi, keterampilan proses sains, dan kemampuan berpikir siswa SMP. Pengembangan MIBP menggunakan model ADDIE. Prosedur pengembangan terdiri dari 5 tahap, yaitu 1 Menganalisis, 2 Mendisain, 3 Mengembangkan dan produksi, 4 Mengimplementasikan, dan 5 Mengevaluasi. Penelitian dilakukan dalam waktu 3 tahun. Pada tahun pertama ini dilakukan analisis kebutuhan dan mendisain MIBP. Subjek penelitian adalah guru IPA SMP Negeri dan Swasta di Kecamatan Buleleng. Pengumpulan data dilakukan dengan wawancara, penyebaran angket, observasi, dan dokumentasi. Analisis data dilakukan secara deskriptif dan interpretatif. Dari hasil analisis diperoleh bahwa kurikulum yang digunakan di SMPN 1,SMPN 2, dan SMPN 4 adalah kurikulum 2013, sedangkan di SMP lainnya masih menggunakan kurikulum 2006. Kemampuan guru bertanya untuk meningkatkan keterampilan proses sains, penguasaan konsep, dan kemampuan berpikir belum optimal. Hal ini ditunjukkan dari jenis pertanyaan yang diajukan guru 85,8 persen bersifat konvergen, dan 14,2 persen bersifat divergen. Berdasarkan pertanyaan menurut Taksonomi Bloom, pertanyaan yang diajukan guru 74,4 persen pertanyaan ingatan, 22,6 persen pemahaman, 2,68 persen aplikasi, dan 0,32 persen analisis. Salah satu yang dapat dilakukan untuk meningkatkan kemampuan guru adalah memfasilitasi pembelajarannya dengan MIBP. Dari karakteristik perkembangan kognitifnya, siswa SMP dapat dibelajarkan dengan strategi inkuiri, dan guru setuju dengan pengembangan MIBP. Kata kunci: Kemampuan berpikir, keterampilan proses sains, Modul Inkuiri Berbasis Pertanyaan, penguasaan konsep Pertanyaan, penguasaan konsep Abstract The purpose of this study was to analyze the need for the development and preparation of question-based inquiry module (QBIM. QBIM was designed conceiv to

  12. ANALISIS STRATEGI PENGEMBANGAN SEKTOR PERTANIAN SUB SEKTOR BAHAN PANGAN DI KABUPATEN BOYOLALI

    Directory of Open Access Journals (Sweden)

    Muhammad Zaenuri

    2017-06-01

    Full Text Available Permasalahan yang dikaji dalam penelitian ini adalah 1. Komoditas tanaman bahan makanan unggulan apa saja yang ada di masing-masing kecamatan di Kabupaten Boyolali, 2 Bagaimana strategi perencanaan pengembangan subsektor tanaman bahan makanan dilihat dari kelengkapan infrastruktur di Kabupaten Boyolali, 3 Bagaimana laju pertumbuhan sektor tanaman bahan makanan yang dimiliki tiap kecamatan di Kabupaten Boyolali. Data yang digunakan adalah data sekunder. Metode analisis data menggunakan analisis Location Quotient (LQ, Shift Share (SS, Klassen Typologi. Berdasarkan hasil penelitian dengan menggunakan analisis Location Quotient (LQ diketahui pengembangan komoditas padi terdapat di Kecamatan Ngemplak, Kecamatan Banyudono, Kecamatan Sawit. Komoditas tanaman jagung terdapat di Kecamatan Selo, Kecamatan Ampel, Kecamatan Cepogo dan Kecamatan Musuk. Komoditas ubi kayu di Kecamatan Klego, kecamatan Simo. Komoditas ubi jalar di Kecamatan Selo, Kecamatan Simo dan Kecamatan Mojosongo. Komoditas kacang tanah ada di Kecamatan Boyolali dan Kecamatan Nogosari. Komoditas kedelai di Kecamatan Juwangi, Kecamatan Sambi, Kecamatn Kemusu dan Kecamatan Wonosegoro. The problems that were in this research is 1 Commodities food plants seed material what it was in each carpel kecamatan in kabupaten boyolali, 2 how strategy sub planning the development of the food crops sector seen from the completeness of the infrastructure in boyolali district, 3 how sector growth rate of plants of food material possessed every sub-district in boyolali district. The data used was secondary data. Data analysis methods using analysis loqation quotient (LQ, shift share (SS, klassen typologi . According to the research using analysis loqation quotient (LQ development rice is in in ngemplak, in banyudono, in palm. Corn is crops in district violoncello, in ampel, in cepogo and in musuk. Commodities cassava in district klego, in simo. Commodities sweet potatoes in in violoncello, in simo and

  13. ANALISIS SPASIAL FAKTOR LINGKUNGAN PADA KEJADIAN DEMAM BERDARAH DENGUE DI KECAMATAN GENUK

    Directory of Open Access Journals (Sweden)

    Kartika Kirana

    2017-10-01

    Full Text Available ABSTRAK Kecamatan Genuk merupakan salah satu kecamatan yang endemis DBD di Kota Semarang. Secara berturut-turut sejak tahun 2012 hingga 2014, Kecamatan Genuk masuk sebagai tiga besar kasus DBD terbanyak. Salah satu faktor yang mempengaruhi kejadian DBD adalah faktor lingkungan. Tujuan penelitian ini adalah untuk mengetahui gambaran dari hasil analisis spasial faktor lingkungan dengan kejadian DBD di Kecamatan Genuk. Jenis penelitian ini deskriptif dengan pendekatan kuantitatif. Fokus penelitian ini adalah kondisi SPAL, penumpukan ban bekas dan sumur gali. Penelitian ini dilakukan di Kecamatan Genuk (Kelurahan Genuksari, Karangroto, Bangetayu Kulon dan Banjardowo pada bulan Maret 2016. Instrumen meliputi lembar observasi, peta lokasi, Global Positioning System (GPS, alat fotografi dan AcrGIS. Analisis data menggunakan SIG. Hasil penelitian menunjukkan bahwa kejadian DBD menggerombol pada beberapa RW yang berdekatan dengan keberadaan penumpukan ban bekas sekitar permukiman dan sumur gali terbuka.   Kata Kunci        : demam berdarah (DBD, lingkungan, analisis spasial     ABSTRACT Genukis one of dengue fever endemic district in Semarang city. Since 2012 until 2014, Genuk involve as the place that has high incidence of Dengue Fever. One of the factors in the incidence Dengue Fever areenvironmental factors.The goals of this research wasto analize spatial environmental factorsin the incidence Dengue Fever in Genukdistrict. This was a quantitative descriptive research with descriptive survey. The unit this research was water puddle on the pilling of the tire, the dug wells, and waste water pipeline that located in Genuk District (Subdistrict of Genuksari, Karangroto, Bangetayu Kulon and Banjardowo at March 2016. The instruments were paper of observation,the  map, GPS, camera and ArcGIS. Data was analyzed with GIS. The study showed that dengue fever transmission was inthe area with pilling of the tire, and the dug wells.   Keywords

  14. ImageJS: Personalized, participated, pervasive, and reproducible image bioinformatics in the web browser

    Directory of Open Access Journals (Sweden)

    Jonas S Almeida

    2012-01-01

    Full Text Available Background: Image bioinformatics infrastructure typically relies on a combination of server-side high-performance computing and client desktop applications tailored for graphic rendering. On the server side, matrix manipulation environments are often used as the back-end where deployment of specialized analytical workflows takes place. However, neither the server-side nor the client-side desktop solution, by themselves or combined, is conducive to the emergence of open, collaborative, computational ecosystems for image analysis that are both self-sustained and user driven. Materials and Methods: ImageJS was developed as a browser-based webApp, untethered from a server-side backend, by making use of recent advances in the modern web browser such as a very efficient compiler, high-end graphical rendering capabilities, and I/O tailored for code migration. Results : Multiple versioned code hosting services were used to develop distinct ImageJS modules to illustrate its amenability to collaborative deployment without compromise of reproducibility or provenance. The illustrative examples include modules for image segmentation, feature extraction, and filtering. The deployment of image analysis by code migration is in sharp contrast with the more conventional, heavier, and less safe reliance on data transfer. Accordingly, code and data are loaded into the browser by exactly the same script tag loading mechanism, which offers a number of interesting applications that would be hard to attain with more conventional platforms, such as NIH′s popular ImageJ application. Conclusions : The modern web browser was found to be advantageous for image bioinformatics in both the research and clinical environments. This conclusion reflects advantages in deployment scalability and analysis reproducibility, as well as the critical ability to deliver advanced computational statistical procedures machines where access to sensitive data is controlled, that is, without

  15. ImageJS: Personalized, participated, pervasive, and reproducible image bioinformatics in the web browser.

    Science.gov (United States)

    Almeida, Jonas S; Iriabho, Egiebade E; Gorrepati, Vijaya L; Wilkinson, Sean R; Grüneberg, Alexander; Robbins, David E; Hackney, James R

    2012-01-01

    Image bioinformatics infrastructure typically relies on a combination of server-side high-performance computing and client desktop applications tailored for graphic rendering. On the server side, matrix manipulation environments are often used as the back-end where deployment of specialized analytical workflows takes place. However, neither the server-side nor the client-side desktop solution, by themselves or combined, is conducive to the emergence of open, collaborative, computational ecosystems for image analysis that are both self-sustained and user driven. ImageJS was developed as a browser-based webApp, untethered from a server-side backend, by making use of recent advances in the modern web browser such as a very efficient compiler, high-end graphical rendering capabilities, and I/O tailored for code migration. Multiple versioned code hosting services were used to develop distinct ImageJS modules to illustrate its amenability to collaborative deployment without compromise of reproducibility or provenance. The illustrative examples include modules for image segmentation, feature extraction, and filtering. The deployment of image analysis by code migration is in sharp contrast with the more conventional, heavier, and less safe reliance on data transfer. Accordingly, code and data are loaded into the browser by exactly the same script tag loading mechanism, which offers a number of interesting applications that would be hard to attain with more conventional platforms, such as NIH's popular ImageJ application. The modern web browser was found to be advantageous for image bioinformatics in both the research and clinical environments. This conclusion reflects advantages in deployment scalability and analysis reproducibility, as well as the critical ability to deliver advanced computational statistical procedures machines where access to sensitive data is controlled, that is, without local "download and installation".

  16. Profiling, analisi delle prestazioni e proposte per l'ottimizzazione del RDBMS MySQL utilizzato dal progetto DIRAC/LHCbDIRAC

    CERN Document Server

    Mesin, Alberto

    Il lavoro presentato in questa tesi riguarda lo studio, l'analisi e la formula- zione di proposte per il miglioramento del database di back-end del progetto DIRAC/LHCbDIRAC. LHCbDIRAC, basato su DIRAC, e il sistema di sot- tomissione per l'accesso all'infrastruttura distribuita Grid per l'esperimento LHCb del CERN. Ad esso e adata la gestione dei job di Produzione, Mer- ge, Ricostruzione degli Eventi e Analisi per i dati sperimentali e simulati. Il sistema utilizza un RDBMS MySQL per la gestione di numerosi databa- se. La volonta di passare ad un motore relazionale e transazionale per la denizione schemi e la possibilita che, in un recente futuro, il DBMS possa rappresentare un serio limite alle prestazioni del sistema stesso hanno reso necessario questo studio. Il lavoro svolto si e concentrato sul proling di un singolo schema relazionale per il quale sono stati utilizzati metodi di analisi e fornite soluzioni ai problemi riscontrati il quanto piu possibile generali e per tanto validi per l'intero sistema. L...

  17. Il difficile cammino dell’analisi musicale in Italia

    Directory of Open Access Journals (Sweden)

    Claudio Annibaldi

    2014-10-01

    Full Text Available Si immaginino gli atti d’un convegno sull’analisi musicale che abbia avuto luogo in un paese come la Francia, la Germania, l’ Inghilterra o gli Stati Uniti. Potrebbe mai accadere che essi vengano pubblicati sostituendo il discorso ufficiale d’apertura dei lavori con un testo tutto nuovo epperò simulante d’esser quello effettivamente pronunciato dall’autore? E potrebbe mai accadere - essendo costui un noto critico musicale e il direttore della collana editoriale comprendente gli atti in questione - che questo nuovo testo sia da lui dedicato a uno sfoggio della propria competenza analitica capace solo di esibire una visione dilettantesca della tecnica musicale tout court? Penso proprio di no. Eppure questo è accaduto in Italia non molti anni fa, quando le Edizioni Unicopli pubblicarono, nella collana dei "Quaderni di Musica/Realtà", gli atti di un convegno sull’analisi musicale tenuto nel 1989 a Reggio Emilia: il primo del genere negli annali della musicologia italiana. L’episodio rende bene l’idea dei pericoli incombenti sul cammino di quegli studiosi che, a far data dal convegno suddetto, si sono adoperati a che la pratica analitica acquisisse anche da noi la dignità scientifica di cui gode, appunto, in paesi come la Francia, la Germania, l’Inghilterra o gli Stati Uniti. Quei pericoli si chiamano ‘dilettantismo tecnico’, ‘arroganza intellettuale’, ‘ vezzo d’ imporre l’uno e l’altra grazie a un qualche tipo di potere personale’, ‘necessità di subire tale imposizione in cambio di qualche vantaggio pratico’.

  18. Analisis Algoritma Pergantian Cache Pada Proxy Web Server Internet Dengan Simulasi

    OpenAIRE

    Nurwarsito, Heru

    2007-01-01

    Pertumbuhan jumlah client internet dari waktu ke waktu terus bertambah, maka respon akses internet menjadi semakin lambat. Untuk membantu kecepatan akses tersebut maka diperlukan cache pada Proxy Server. Penelitian ini bertujuan untuk menganalisis performansi Proxy Server pada Jaringan Internet terhadap penggunaan algoritma pergantian cache-nya.Analisis Algoritma Pergantian Cache Pada Proxy Server didesain dengan metoda pemodelan simulasi jaringan internet yang terdiri dari Web server, Proxy ...

  19. ANALISIS FAKTOR-FAKTOR YANG MENDORONG WISATAWAN MELAKUKAN KEPUTUSAN PEMBELIAN TIKET PESAWAT MELALUI MOBILE BOOKING PADA SITUS TRAVELOKA.COM

    Directory of Open Access Journals (Sweden)

    Erni Muliana

    2016-07-01

    Full Text Available Pembelian kebutuhan perjalanan wisata secara online merupakan bagian dari transaksi business to-customer (B2C. Produk yang ditawarkan biasanya terdiri dari: pemesanan paket wisata, penjualan tiket pesawat dan kereta api, kamar hotel dan penyewaan transportasi. Penelitian dilakukan dengan tujuan untuk mengetahui faktor-faktor yang mendorong wisatawan melakukan keputusan pembelian tiket pesawat melalui mobile booking pada situs Traveloka.com serta faktor yang paling banyak berkontribusi dalam menentukan keputusan pembelian tersebut. Teknik pengumpulan data yang digunakan adalah kuesioner online dan kuesioner yang disebarkan secara langsung (offline kepada 250 responden, penentuan responden ditetapaka menggunakn metode purposive sampling, sedangkan teknik analisis data yang digunakan adalah teknik analisis faktor. Hasil analisis faktor yang didapatakan menjelaskan 67,066% dari keseluruhan total variance, dan hasil analisis data menunjukkan empat faktor terbentuk yang mendorong wisatawan melakukan keputusan pembelian tiket pesawat melalui mobile booking pada situs Traveloka.com, yaitu: kemudahan dan sistem informasi website (24,396 %, pelayanan konsumen/customer service (15,211%, citra perusahaan (14,681 %, dan motivasi pembelian (12,779%, adapun faktor yang paling berkontribusi dalam mendorong wisatawan melakukan keputusan pembelian tiket pesawat melalui mobile booking pada situs Traveloka.com adalah faktor terbentuk yang memiliki faktor laoding tertinggi dari keseluruhan faktor yang terbentuk, yaitu faktor “Kemudahan dan Sistem Informasi Website”, faktor ini terdiri dari 13 variabel yakni: (1 Kemudahan pencarian situs web, (2 kecepatan waktu mengakses (load time, (3 nama domain perusahaan, (4 kemudahan pemesanan, (5 Informasi yang lengkap, (6 Informasi yang akurat, (7 Informasi yang menarik, (8 Pemaparan informasi yang tepat, (9 Ketersediaan dan aksesibilitas, (10 Harga yang kompetitif, (11 Pengalaman secara keseluruhan, (12 Keamanan data

  20. PENGKLASIFIKASIAN KARAKTERISTIK MAHASISWA BARU DALAM MEMILIH PROGRAM STUDI MENGGUNAKAN ANALISIS CLUSTER

    Directory of Open Access Journals (Sweden)

    Maxsi Ary

    2016-03-01

    Full Text Available Abstract - Object Clustering is one of the object mining process which aims to partition an existing object into one or more cluster objects based on their characteristics. Private Universities is one of the alternatives for the community colleges to meet increased demand for educational needs. The number of private colleges, especially in Bandung and generally in Indonesia is quite a lot. The number of colleges and universities means used to attract prospective students to be an interesting thing to study. As a reason for the intense competition in the search for new students, no doubt there are some ways that actually do not need to be done. Issues raised, namely classify new students of characteristics in selecting a course using cluster analysis. Data obtained from the questionnaire prospective new students in February 2014 Data processing using SPSS. The results using analysis SPSS aiming easier to describe the characteristics of each group of new students in choosing courses. Keywords: Clustering, characteristics of students, courses, cluster analysis Abstrak - Pengelompokan Objek (object clustering adalah salah satu proses dari objek mining yang bertujuan untuk mempartisi objek yang ada kedalam satu atau lebih cluster objek berdasarkan karakteristiknya. Perguruan tinggi swasta merupakan salah satu perguruan tinggi alternatif bagi masyarakat untuk menghadapi peningkatan permintaan terhadap kebutuhan pendidikan. Jumlah perguruan tinggi swasta khususnya di Bandung dan umumnya di Indonesia berjumlah cukup banyak. Jumlah perguruan tinggi dan cara yang digunakan perguruan tinggi untuk menarik minat calon mahasiswa menjadi hal yang menarik untuk dikaji. Sebagai alasan ketatnya persaingan dalam mencari calon mahasiswa baru, tidak dipungkiri terdapat beberapa cara yang dilakukan yang sebetulnya tidak perlu dilakukan. Persoalan yang dikemukakan yaitu mengklasifikasikan karakteristik mahasiawa baru dalam memilih program studi menggunakan analisis

  1. The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species.

    Science.gov (United States)

    Maciag, Anna E; Chakrapani, Harinath; Saavedra, Joseph E; Morris, Nicole L; Holland, Ryan J; Kosak, Ken M; Shami, Paul J; Anderson, Lucy M; Keefer, Larry K

    2011-02-01

    Non-small-cell lung cancer is among the most common and deadly forms of human malignancies. Early detection is unusual, and there are no curative therapies in most cases. Diazeniumdiolate-based nitric oxide (NO)-releasing prodrugs are a growing class of promising NO-based therapeutics. Here, we show that O(2)-(2,4-dinitrophenyl)-1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K) is a potent cytotoxic agent against a subset of human non-small-cell lung cancer cell lines both in vitro and as xenografts in mice. JS-K treatment led to 75% reduction in the growth of H1703 lung adenocarcinoma cells in vivo. Differences in sensitivity to JS-K in different lung cancer cell lines seem to be related to their endogenous levels of reactive oxygen species (ROS)/reactive nitrogen species (RNS). Other related factors, levels of peroxiredoxin 1 (PRX1) and 8-oxo-deoxyguanosine glycosylase (OGG1), also correlated with drug sensitivity. Treatment of the lung adenocarcinoma cells with JS-K resulted in oxidative/nitrosative stress in cells with high basal levels of ROS/RNS, which, combined with the arylating properties of the compound, was reflected in glutathione depletion and alteration in cellular redox potential, mitochondrial membrane permeabilization, and cytochrome c release. Inactivation of manganese superoxide dismutase by nitration was associated with increased superoxide and significant DNA damage. Apoptosis followed these events. Taken together, the data suggest that diazeniumdiolate-based NO-releasing prodrugs may have application as a personalized therapy for lung cancers characterized by high levels of ROS/RNS. PRX1 and OGG1 proteins, which can be easily measured, could function as biomarkers for identifying tumors sensitive to the therapy.

  2. ANALISIS KELAYAKAN FINANSIAL WISATA AIR WADUK JATIGEDE KABUPATEN SUMEDANG

    Directory of Open Access Journals (Sweden)

    Bambang Susanto

    2016-04-01

    pendahuluan agar manfaatnya jauh lebih besar dari biaya yang dikeluarkan. Oleh sebab itu untuk kepentingan ilmiah perlu dilakukan kajian akademisnya berupa Analisis kelayakan Finansial. Berdasarkan analisis kelayakan keuangan   ,dapat  disimpulkan bahwa wisata air di Waduk jatigede Kabupaten Sumedang  memberikan manfaat yang lebih dibandingkan dengan biaya yang dikeluarkan . ini dapat dilihat dari hasil analisis net present value yang positif, internal rate of return yang lebih besar dari tingkat bunga bank serta benefit cost yang lebih besar dari satu. Kata Kunci: Kelayakan Finansial; Wisata Air.

  3. Metode Pengumpulan dan Analisis Data : Lang Kah Vital Proses Penelitian

    OpenAIRE

    Suprapto, Agus .

    2005-01-01

    The process of data collection and. analysis is one of chains in scientific method that should be done in a research. This part later on will determine the right method in searching and analyzing a way in solving a problem. The data collected should be the ones which are relevant which the essence of research problems, so that the next interpreted data will eventually be concluded as valid. keywords: Pengumpulan data, analisis data,dan metode ilmiah

  4. Text Mining Untuk Analisis Sentimen Review Film Menggunakan Algoritma K-Means

    OpenAIRE

    Setyo Budi

    2017-01-01

    Kemudahan manusia didalam menggunakan website mengakibatkan bertambahnya dokumen teks yang berupa pendapat dan informasi. Dalam waktu yang lama dokumen teks akan bertambah besar. Text mining merupakan salah satu teknik yang digunakan untuk menggali kumpulan dokumen text sehingga dapat diambil intisarinya. Ada beberapa algoritma yang di gunakan untuk penggalian dokumen untuk analisis sentimen, salah satunya adalah K-Means. Didalam penelitian ini algoritma yang digunakan adalah K-Means. Hasil p...

  5. ANALISIS KEAMANAN DATA PADA BLOCK CIPHER ALGORITMA KRIPTOGRAFI RSA

    Directory of Open Access Journals (Sweden)

    Fadhillah Azmi

    2017-01-01

    Full Text Available Komunikasi adalah proses dasar dari pertukaran informasi. Efektifitas komunikasikomputer secara umum adalah melalui internet atau beberapa saluran komunikasi lainnya.Tujuan utama tulisan ini adalah berdasarkan pada analisis hasil yang diberikan Weinermengatakan bahwa jika private key d digunakan dalam algoritma kriptografi RSA kurang darin292, maka sistem tersebut kurang aman. Di sini penulis menganalisa pada hasil yang diberikanoleh Weiner dan mencoba untuk meningkatkan range dari private key d sampai n0.5. Karena nadalah perkalian p dan q, yang mana bilangan relative prima. Sehingga mempengaruhi kinerjaenkripsi algoritma yang lebih aman.

  6. [Application of multiplex PCR for the screening of genotyping system for the rare blood groups Fy(a-), s-,k-,Di(b-) and Js(b-)].

    Science.gov (United States)

    Jiao, Wei; Xie, Li; Li, Hailan; Lan, Jiao; Mo, Zhuning; Yang, Ziji; Liu, Fei; Xiao, Ruiping; He, Yunlei; Ye, Luyi; Zhu, Ziyan

    2014-04-01

    To screen rare blood groups Fy(a-), s-, k-, Di(b-) and Js(b-) in an ethnic Zhuang population. Sequence-specific primers were designed based on single nucleotide polymorphism (SNP) sites of blood group antigens Fy(b) and s. A specific multiplex PCR system I was established. Multiplex PCR system II was applied to detect alleles antigens Di(b), k, Js(b)1910 and Js(b) 2019 at the same time. The two systems was were used to screen for rare blood group antigens in 4490 randomly selected healthy donors of Guangxi Zhuang ethnic origin. We successfully made the multiplex PCR system I. We detected the rare blood group antigens using the two PCR system. There are five Fy(a-), three s(-), two Di(b-) in 4490 Guangxi zhuang random samples. The multiplex PCR system I has achieved good accuracy and stability. With multiplex PCR systems I and II, 4490 samples were screened. Five Fy(a-), three s(-) and two Di(b-) samples were discovered. Multiplex PCR is an effective methods, which can be used for high throughput screening of rare blood groups. The rare blood types of Guangxi Zhuang ethnic origin obtained through the screening can provide valuable information for compatible blood transfusion. Through screening we obtained precious rare blood type materials which can be used to improve the capability of compatible infusion and reduce the transfusion reactions.

  7. ANALISIS SOAL JENJANG KOGNITIF TAKSONOMI BLOOM REVISI PADA BUKU SEKOLAH ELEKTRONIK (BSE BIOLOGI SMA

    Directory of Open Access Journals (Sweden)

    Aa Juhanda

    2016-11-01

    Penelitian ini bertujuan untuk menganalisis kemunculan soal jenjang kognitif Bloom Revisi pada Buku Sekolah Elektronik (BSE Biologi SMA. Subjek penelitian adalah 1.650 soal yang terdapat pada BSE Edisi 2009. Instrumen yang digunakan adalah lembar analisis dokumen yang di dalamnya memuat informasi seperti kode soal, soal, dan jenis tingkatan kognitif taksonomi Bloom Revisi. Analisis data dilakukan secara kuantitatif dan kualitatif. Hasil penelitian menunjukkan bahwa rerata persentase kemunculan cukup tinggi diperoleh pada soal yang mengembangkan keterampilan berpikir tingkat rendah (Lower-Order Thinking Skills yaitu soal C1 (mengingat sebesar 46,60% dan C2 (memahami sebesar 47,99%, meskipun untuk C3 (menerapkan persentasenya masih rendah (0,28%. Rerata persentase kemunculan soal yang mengembangkan keterampilan tingkat tinggi (Higher-Order Thinking Skills mulai dari soal C4 (menganalisis sampai dengan C6 (mencipta memiliki rerata persentase yang rendah. Oleh karena itu, kemunculan soal jenjang kognitif Bloom Revisi pada BSE khususnya yang mengembangkan Higher-Order Thinking Skills masih perlu untuk ditingkatkan.

  8. Deteksi Kerusakan Batang Rotor Pada Motor Induksi Menggunakan Analisis Arus Mula Berbasis Hilbert Transform

    Directory of Open Access Journals (Sweden)

    Isti Qomah

    2017-01-01

    Full Text Available Kerusakan batang rotor merupakan salah satu jenis kerusakan pada motor induksi yang dapat menyebabkan masalah serius. Kerusakan tersebut dapat mencapai 5% - 10% dari seluruh kasus gangguan motor induksi. Oleh karena itu, perlu adanya diagnosis awal yang mendeteksi adanya gangguan pada rotor motor induksi, agar dapat dilakukan perbaikan lebih cepat dan tanggap sebelum terjadi gangguan yang lebih besar. Tugas Akhir ini membahas terkait teknik deteksi kerusakan batang rotor pada motor induksi dengan menggunakan analisis arus mula. Sistem yang digunakan berbasis  decomposition wavelet transform terlebih dahulu kemudian dilanjutkan dengan analisis berbasis hilbert transform sebagai perangkat pengolahan sinyal sehingga mampu mendeteksi motor dalam keadaan sehat atau mengalami kerusakan. Pengujian sistem dilakukan dalam beberapa kondisi, yaitu kondisi tanpa beban dan berbeban. Selain itu, kondisi yang diberikan adalah kecacatan mulai dai 1BRB hingga 3BRB. Hasil pengujian membuktikan bahwa decomposition wavelet transform dan Hilbert transform mampu mendeteksi perbedaan kondisi pada motor induksi normal ataupun rusak pada batang rotor.

  9. Stabilization of the nitric oxide (NO) prodrugs and anticancer leads, PABA/NO and Double JS-K, through incorporation into PEG-protected nanoparticles.

    Science.gov (United States)

    Kumar, Varun; Hong, Sam Y; Maciag, Anna E; Saavedra, Joseph E; Adamson, Douglas H; Prud'homme, Robert K; Keefer, Larry K; Chakrapani, Harinath

    2010-02-01

    We report the stabilization of the nitric oxide (NO) prodrugs and anticancer lead compounds, PABA/NO (O(2)-{2,4-dinitro-5-[4-(N-methylamino)benzoyloxy]phenyl} 1-(N,N-dimethylamino)diazen-1-ium-1,2-diolate) and "Double JS-K" 1,5-bis-{1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diol-2-ato}-2,4-dinitrobenzene, through their incorporation into polymer-protected nanoparticles. The prodrugs were formulated in block copolymer-stabilized nanoparticles with sizes from 220 to 450 nm by a novel rapid precipitation process. The block copolymers, with polyethylene glycol (PEG) soluble blocks, provide a steric barrier against NO prodrug activation by glutathione. Too rapid activation and NO release has been a major barrier to effective administration of this class of compounds. The nanoparticle stabilized PABA/NO are protected from attack by glutathione as evidenced by a significant increase in time taken for 50% decomposition from 15 min (unformulated) to 5 h (formulated); in the case of Double JS-K, the 50% decomposition time was extended from 4.5 min (unformulated) to 40 min (formulated). The more hydrophobic PABA/NO produced more stable nanoparticles and correspondingly more extended release times in comparison with Double JS-K. The hydrophobic blocks of the polymer were either polystyrene or polylactide. Both blocks produced nanoparticles of approximately the same size and release kinetics. This combination of PEG-protected nanoparticles with sizes appropriate for cancer targeting by enhanced permeation and retention (EPR) and delayed release of NO may afford enhanced therapeutic benefit.

  10. Irradiation dose control of chicken meat processing with alanine/ESR dosimetric system

    International Nuclear Information System (INIS)

    Miyagusku, L.; Chen, F.; Kuaye, A.; Castilho, C.J.C.; Baffa, O.

    2007-01-01

    Irradiation of foodstuff is a well-known food preservation technique. In Brazil spices are already irradiated for sanitary and preservation reasons. Chicken meat is an important commodity; Brazil is the second largest world producer and the largest world exporter. The shelf-life of chicken meat is limited by the presence of micro-organisms and enzyme activity and together with other preservation techniques irradiation seems to be an attractive option. In this study the dose delivered to frozen chicken cuts was measured and compared with the prescribed value. Chicken breast cuts were analyzed for 39 days for their microbiological activity, chemical and organoleptic properties. Cylindrical dosimeters were prepared using the weight composition of 80% of DL-alanine (Sigma Co), used without any further treatment except drying, and 20% of paraffin. The dosimeters having 4.7 mm diameter and 12 mm length were inserted in a build-up cap. Dosimeters were placed inside cardboard boxes containing frozen chicken breast cuts, packed in styrofoam trays wrapped with plastic film. The boxes were irradiated in an industrial 60 Co irradiator (Nordion JS 7500) with a dose rate of 4 kGy/h. First derivative ESR signals were obtained in a VARIAN E-4 spectrometer operating at X-band (ν∼9GHz) and equipped with a rectangular cavity (TE-102, model E-231). The cavity was constantly purged with dry nitrogen and modulated at 100 KHz with 0.5 mT peak to peak. A calibration curve was made for a few dosimeters from the same batch and used to obtain the dose from the ESR signal intensity. A batch of six boxes was irradiated at each experiment with prescribed doses of 1.5, 3.0 and 7.0 kGy. Considering that the larger the radiation dose the greater is the probability of finding a product with its sensorial characteristics altered (odor of burned meat), we conclude that a dose of 3 kGy would be more adequate, taking into account the microbiological and sensorial aspects

  11. Analisis Arus Kas Terkait Kebijakan Uang Kuliah Tunggal di Perguruan Tinggi Negeri Badan Hukum

    Directory of Open Access Journals (Sweden)

    Surtiati Surtiati

    2017-05-01

    Full Text Available The aims of the research were to analyze cash flow and compare tuition income in a State University with Legal Entity of “XYZ” for its first year TPB students (the First Common Year and of the first year until the fourth year before and after implementation of the single tuition fee system and formulate the management policies for the tuition income after the single tuition fee system. Analysis of cash flows consisted of cash ratio, quick ratio and current ratio. Paired t-test was used to analyze differences between single tuition fee income and non single tuition fee income. Based on the cash flow analysis, it is found that the University of “XYZ” has a liquid financial condition. The significant difference is, moreover, detected from the paired t-test analysis between single and non single tuition fee of total income from the first year student tuition. However, there is no difference detected when the analysis was conducted for total income from all four year tuitions. Management policies tuition income after the single tuition fee system payment delays should be minimized so that tuition fee funds can be completely collected. The allocation of fees to the faculty/department was originally based on the BPMP, and BPMK uses a tariff system so that cost per subject does not necessarily correspond with the needs. This is not in accordance with the single tuition fee system that is based on the unit cost. This means that the cost of the course is based on real needs, not based on the rates set.Keywords: cash flow analysis, state university with legal entity, single tuition feeABSTRAKPenelitian ini bertujuan menganalisis arus kas, mengkaji perbedaan penerimaan SPP S1 Reguler satu tahun pertama bagi mahasiswa TPB dan tahun pertama sampai tahun ke empat sebelum dan sesudah kebijakan UKT di PTN Badan Hukum “XYZ. Selanjutnmya, merumuskan kebijakan pengelolaan SPP S1 reguler sesudah UKT. Analisis arus kas terdiri dari rasio kas, rasio cepat

  12. The Nitric Oxide Prodrug JS-K Is Effective against Non–Small-Cell Lung Cancer Cells In Vitro and In Vivo: Involvement of Reactive Oxygen SpeciesS⃞

    Science.gov (United States)

    Chakrapani, Harinath; Saavedra, Joseph E.; Morris, Nicole L.; Holland, Ryan J.; Kosak, Ken M.; Shami, Paul J.; Anderson, Lucy M.; Keefer, Larry K.

    2011-01-01

    Non–small-cell lung cancer is among the most common and deadly forms of human malignancies. Early detection is unusual, and there are no curative therapies in most cases. Diazeniumdiolate-based nitric oxide (NO)-releasing prodrugs are a growing class of promising NO-based therapeutics. Here, we show that O2-(2,4-dinitrophenyl)-1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate (JS-K) is a potent cytotoxic agent against a subset of human non–small-cell lung cancer cell lines both in vitro and as xenografts in mice. JS-K treatment led to 75% reduction in the growth of H1703 lung adenocarcinoma cells in vivo. Differences in sensitivity to JS-K in different lung cancer cell lines seem to be related to their endogenous levels of reactive oxygen species (ROS)/reactive nitrogen species (RNS). Other related factors, levels of peroxiredoxin 1 (PRX1) and 8-oxo-deoxyguanosine glycosylase (OGG1), also correlated with drug sensitivity. Treatment of the lung adenocarcinoma cells with JS-K resulted in oxidative/nitrosative stress in cells with high basal levels of ROS/RNS, which, combined with the arylating properties of the compound, was reflected in glutathione depletion and alteration in cellular redox potential, mitochondrial membrane permeabilization, and cytochrome c release. Inactivation of manganese superoxide dismutase by nitration was associated with increased superoxide and significant DNA damage. Apoptosis followed these events. Taken together, the data suggest that diazeniumdiolate-based NO-releasing prodrugs may have application as a personalized therapy for lung cancers characterized by high levels of ROS/RNS. PRX1 and OGG1 proteins, which can be easily measured, could function as biomarkers for identifying tumors sensitive to the therapy. PMID:20962031

  13. ANALISIS DEREPLIKASI UNTUK IDENTIFIKASI SENYAWA ANTIBAKTERI SPONGE Axinella sp. DARI PERAIRAN KEPULAUAN KARIMUNJAWA

    Directory of Open Access Journals (Sweden)

    Hedi Indra Januar

    2009-06-01

    Full Text Available Riset ini bertujuan untuk mengidentifikasi senyawa antibakteri pada Axinella sp. yang diambil dari kepulauan Karimunjawa dengan metode dereplikasi menggunakan LCMS (Liquid Chromatography Mass Spectrometer dan FT-MS (Fourier Transfer Mass Spectrometer. Data pola spektra massa dan LC-MS menunjukkan adanya tiga senyawa terbrominasi yang mungkin memiliki bioakfivitas antibakteri. Analisis massa akurat (limit kesalahan di bawah 20 ppm menggunakan FT-MS menemukan bahwa ketiga senyawa tersebut memliki monosotop negatif (M-H pada m/z 321,9931 [senyawa (a]; m/z 383,9089 [senyawa (b]; dan m/z 385,9249 [senyawa (c]. Analisis komposisi kimia dari besaran massa tersebut yang menggunakan Elemental Composition Calculator menemukan bahwa komposisi kimia dari ketiga senyawa tersebut adalah C11H10N5O2Br (a, C11H9N5Br2 (b dan C11H11Br2N5O (c. Penelusuran struktur kima yang didasarkan pada komposisi tersebut di database MarinLit 2008 (Database struktur kimia senyawa-senyawa dari biota laut menemukan bahwa ketiga senyawa tersebut merupakan hymeniadisine (a, 3-bromohymenialdiside (b, dan dibromophakelin (c.

  14. Analisis interferensi T-DAB dan TV Analog pada pita Very High Frequency (VHF

    Directory of Open Access Journals (Sweden)

    Kasmad Ariansyah

    2014-09-01

    Full Text Available Kehadiran teknologi digital telah membawa perubahan di dalam berbagai aspek kehidupan, tak terkecuali di dunia penyiaran. Digitalisasi dibidang penyiaran diyakini dapat memberikan manfaat dalam hal efisiensi spektrum frekuensi radio. Berkaitan dengan penyiaran radio, Menteri  Komunikasi  dan  Informatika telah menetapkan DAB family sebagai standard penyiaran radio digital di Indonesia. Kajian dilakukan untuk mendapatkan jarak minimum yang diperlukan  antara sistem T-DAB dan TV analog sebagai solusi terhadap kemungkinan interferensi. Analisis dilakukan dengan bantuan SEAMCAT. Berdasarkan hasil analisis disimpulkan bahwa  kanal  A  T-DAB  merupakan  kanal yang paling rentan terhadap interferensi; Untuk mencapai probabilitas interferensi maksimum 5%, separasi geograpis minimum antara cakupan terluar TV analog kanal n dan transmitter terluar pada jaringan SFN T-DAB untuk kanal (n- 1D, nA, nB, nC berturut-turut adalah 220 Km, 290 Km, 145 Km dan  40  Km.  Sedangkan  untuk  kanal  nD  dan  (n+1A  dapat dioperasikan tanpa separasi geograpis dengan TV analog.

  15. Solution strengthened ferritic ductile iron ISO 1083/JS/500-10 provides superior consistent properties in hydraulic rotators

    Directory of Open Access Journals (Sweden)

    Dr. Richard Larker

    2009-11-01

    Full Text Available Consistent mechanical and machining properties are essential in many applications where ductile irons offer the most cost-effective way to produce structural parts. In the production of hydraulic rotators, dimensional tolerances are typically 20 μm to obtain designated performance. For castings where intermediate strength and ductility is required, it is common knowledge that conventional ferritic-pearlitic ductile irons such as ISO 1083/500-7 show large hardness variations. These are mainly caused by the notoriously varying pearlite content, both at different locations within a part and between parts in the same or different batches. Cooling rate variations due to different wall thickness and position in the molding box, as well as varying amounts of pearlite-stabilizing elements, all contribute to detrimental hardness variations. The obvious remedy is to avoid pearlite formation, and instead obtain the necessary mechanical properties by solution strengthening of the ferritic matrix by increasing silicon content to 3.7wt% –3.8wt%. The Swedish development in this fi eld 1998 resulted in a national standardization as SS 140725, followed in 2004 by ISO 1083/JS/500-10. Indexator AB decided 2005 to specify JS/500-10 for all new ductile iron parts and to convert all existing parts. Improvements include reduction by 75% in hardness variations and increase by 30% in cutting tool life, combined with consistently better mechanical properties.

  16. jsPhyloSVG: a javascript library for visualizing interactive and vector-based phylogenetic trees on the web.

    Science.gov (United States)

    Smits, Samuel A; Ouverney, Cleber C

    2010-08-18

    Many software packages have been developed to address the need for generating phylogenetic trees intended for print. With an increased use of the web to disseminate scientific literature, there is a need for phylogenetic trees to be viewable across many types of devices and feature some of the interactive elements that are integral to the browsing experience. We propose a novel approach for publishing interactive phylogenetic trees. We present a javascript library, jsPhyloSVG, which facilitates constructing interactive phylogenetic trees from raw Newick or phyloXML formats directly within the browser in Scalable Vector Graphics (SVG) format. It is designed to work across all major browsers and renders an alternative format for those browsers that do not support SVG. The library provides tools for building rectangular and circular phylograms with integrated charting. Interactive features may be integrated and made to respond to events such as clicks on any element of the tree, including labels. jsPhyloSVG is an open-source solution for rendering dynamic phylogenetic trees. It is capable of generating complex and interactive phylogenetic trees across all major browsers without the need for plugins. It is novel in supporting the ability to interpret the tree inference formats directly, exposing the underlying markup to data-mining services. The library source code, extensive documentation and live examples are freely accessible at www.jsphylosvg.com.

  17. ANALISIS CURAH HUJAN PANTAI BARAT SUMATERA BAGIAN UTARA PERIODE 1994-2007

    Directory of Open Access Journals (Sweden)

    Indra Gustari

    2009-07-01

    Full Text Available Dari data curah hujan di pantai barat Sumatera bagian utara dilakukan analisis spektrum daya untuk mengetahui pola curah hujan di daerah tersebut, selanjut dilihat hubungannya dengan intensitas monsun,  Indian Ocean Dipole Mode (IODM dan El-Nino Southern Oscillation (ENSO. Hasil analisis menunjukkan bahwa pola curah hujan di pantai barat Sumatera bagian utara memiliki dua puncak dan sangat dipengaruhi oleh faktor cuaca dengan dengan osilasi satu tahunan (annual oscillation, dan setengah tahunan (semi-annual oscillation dan ditemukan hubungan yang kuat antara variabilitas monsun dan IODM. Pola hujan didaerah ini tidak memperlihatkan pengaruh ENSO.   The data of Rainfall in the west coast of northern Sumatera were analyzed through power spectrum analyzer to find out the rainfall pattern in that area and to look at the relationship between rainfall pattern and monsoon intensity, Indian Ocean Dipole Mode (IODM and El-Nino Southern Oscillation (ENSO. The result of this analysis shows that the main rainfall pattern in the west coast of northern Sumatera has two peaks and is very much influenced by the factor of weather with annual oscillation and semi-annual oscillation, there is a strong relationship between monsoon variability and IODM, and the influence of ENSO on the rainfall in this region is not significant.

  18. {gamma} irradiation facility at ENEA-Casaccia Centre (Rome); Impianto di irraggiamento {gamma} Calliope presso il Centro Ricerche ENEA-Casaccia (Roma)

    Energy Technology Data Exchange (ETDEWEB)

    Baccaro, S; Cecilia, A; Pasquali, A [ENEA, Centro Ricerche Casaccia, Rome (Italy). Unita scientifico tecnica Tecnologie Fisiche Avanzate

    2005-09-15

    A description of Calliope {gamma} irradiation plant of ENEA-Casaccia Centre (Rome) is presented in this paper. In particular the main characteristics of the irradiation facility necessary to define time and irradiation procedure are summarised. The plant is equipped with dosimetric services that evaluate absorbed doses in materials during irradiation. Dosimetric techniques used are Fricke, RedPerspex and alanine-ESR dosimetries. In the first case, absorbed dose is determined by chemical changes induced in a solution by irradiation and the second method uses the optical density increase induced in dosimeter by irradiation. The last method is based on the analysis of the free radical concentration induced in {alpha}-alanine amino-acid during irradiation. The paper provides also a simulation of the {gamma} radiation field inside the irradiation cell realised by using FLUKA code, which includes a good description of the electromagnetic physics down to about 0.1 KeV. [Italian] In questo lavoro viene descritto l'impianto di irraggiamento {gamma} Calliope del Centro Ricerche ENEA-Casaccia (Roma). In particolare vengono riportate le principali caratteristiche dell'impianto di irraggiamento necessarie per definire le modalita di tempo e di irraggiamento. Le tecniche dosimetriche utilizzate sono: la dosimetria di Fricke, la Red-Perspex e quella ESR con alanina. Nel primo caso la dose assorbita e misurata attraverso cambiamenti chimici indotti dalla radiazione in una soluzione mentre nel secondo metodo si utilizza l'aumento della densita ottica del dosimetro dovuto all'irraggiamento. Infine la tecnica ESR ad alanina si basa sull'analisi dei radicali liberi indotti dall' irraggiamento nell' aminoacido {alpha}-alanina. Nel lavoro e anche fornita una simulazione del campo di radiazione all'interno della cella di irraggiamento realizzata con il codice FLUKA, che include l'ottima descrizione dei processi di iterazione elettromagnetici fino ad un'energia di 0.1 KeV.

  19. Complete Genome Sequences of Porcine Epidemic Diarrhea Virus Strains JSLS-1/2015 and JS-2/2015 Isolated from China.

    Science.gov (United States)

    Tao, Jie; Li, Benqiang; Zhang, Chunling; Liu, Huili

    2016-11-10

    Two porcine epidemic diarrhea virus (PEDV) strains, JSLS-1/2015 and JS-2/2015, were isolated from piglets with watery diarrhea in South China. Two genomic sequences were highly homologous to the attenuated DR13 strain. Furthermore, JSLS-1/2015 contains a 24-amino-acid deletion in open reading frame 1b, which was first reported in PEDV isolates. Copyright © 2016 Tao et al.

  20. Draft Genome Sequence of an Endophytic Fungus, Gaeumannomyces sp. Strain JS-464, Isolated from a Reed Plant, Phragmites communis.

    Science.gov (United States)

    Kim, Jung A; Jeon, Jongbum; Kim, Ki-Tae; Choi, Gobong; Park, Sook-Young; Lee, Hyun-Jung; Shim, Sang-Hee; Lee, Yong-Hwan; Kim, Soonok

    2017-08-03

    An endophytic fungus, Gaeumannomyces sp. strain JS-464, is capable of producing a number of secondary metabolites which showed significant nitric oxide reduction activity. The draft genome assembly has a size of 53,151,282 bp, with a G+C content of 53.11% consisting of 80 scaffolds with an N 50 of 7.46 Mbp. Copyright © 2017 Kim et al.

  1. ANALISIS PENGARUH CUSTOMER RELATIONSHIP MANAGEMENT TERHADAP KEPUASAN PELANGGAN PADA PT TELKOMSEL DI MAKASSAR

    OpenAIRE

    ANANDA, RACHMA RESKY

    2015-01-01

    2015 Analisis Pengaruh Customer Relationship Management Terhadap Kepuasan Pelanggan Pada PT Telkomsel di Makassar Analysis of Customer Relationship Management Influence to Customer Satisfaction at PT Telkomsel in Makassar Rachma Resky Ananda Muh. Asdar Yansor Djaya Tujuan dari penelitian ini adalah untuk menganalisis pengaruh Customer Relationship (continuity marketing, one to one marketing dan partnering atau co-marketing) terhadap k...

  2. KERAGAAN WARNA IKAN CLOWN BIAK (Amphiprion percula POPULASI ALAM DAN BUDIDAYA BERDASARKAN ANALISIS GAMBAR DIGITAL

    Directory of Open Access Journals (Sweden)

    Ruby Vidia Kusumah

    2015-09-01

    Full Text Available Penelitian ini bertujuan untuk mengkaji keragaan warna ikan clown Biak (Amphiprion percula populasi alam dan budidaya berdasarkan analisis gambar digital sebagai dasar upaya pemuliaannya. Gambar digital diambil dari koleksi ikan clown Biak Balai Besar Perikanan Budidaya Laut Lampung, Balai Besar Penelitian dan Pengembangan Budidaya Laut Gondol, Bali; serta pengumpul ikan hias di Denpasar, Bali menggunakan kamera digital Canon EOS 600D. Pola warna dikarakterisasi secara visual terhadap variasi strip hitam dan putih pada dasar badan oranye, jenis warna dianalisis menggunakan ImageJ 1.49s, persentase penutupan warna dilakukan dengan Adobe Photoshop CS5. Pola warna dikarakterisasi oleh strip hitam tebal, tipis, gelap, pudar, terputus, bergabung, serta strip putih normal, pelana, spot, melebar, dan terputus. Warna hitam alam dikarakterisasi oleh hue (H: 300-60º, saturation (S: 8%-56%, brightness (B: 3%-19%, sedangkan budidaya H: 300-23º, S: 9%-71%, B: 4%-20%. Warna oranye alam H: 19-33º, S: 88%-98%, B: 47%-85%, dan budidaya H: 14-29º, S: 86%-99%, B: 38%-82%. Warna putih alam H: 36-270º; S: 1%-13%, B: 66%-88%, dan budidaya H: 0-229º, S: 0%-14%, B: 55%-87%. Persentase penutupan warna badan didominasi warna oranye dengan rata-rata 45% untuk populasi alam dan 57% untuk populasi budidaya. Keragaan warna ikan clown Biak dapat diarahkan pada pembentukan strain misbar, picasso, spot (domino, dan onyx. Metode analisis gambar digital sangat potensial digunakan untuk analisis keragaan warna ikan hias.

  3. Analisis Kelembagaan Rantai Pasok Telur Ayam Ras Peternakan Rakyat Di Jawa Barat

    OpenAIRE

    Sejati, Wahyuning K

    2011-01-01

    Dalam konteks pengembangan pasar komoditas dan peningkatan kesejahteraan peternak rakyat perlu dipahami secara baik karakteristik dan kelembagaan petani, pemasok, dan pasar. Tulisan ini bertujuan untuk menganalisis kelembagaan rantai pasok peternak-pemasok-pasar komoditas telur ayam ras yang meliputi: (1) identifikasi kelembagaan peternakan rakyat ayam ras petelur; (2) analisis kelembagaan rantai pasok komoditas telur; dan (3) antisipasi kelembagaan introduksi rantai pasok telur ayam ras pete...

  4. ANALISIS SENSITIVITAS TURBULENSI ALIRAN PADA KANAL BAHAN BAKAR PWR BERBASIS CFD

    Directory of Open Access Journals (Sweden)

    Endiah Puji Hastuti

    2015-04-01

    Full Text Available Turbulensi aliran pendingin pada proses perpindahan panas berfungsi untuk meningkatkan nilai koefisien perpindahan panas, tidak terkecuali aliran dalam kanal bahan bakar. Program CFD (CFD=computational fluid dynamics, FLUENT adalah program komputasi berbasis elemen hingga (finite element yang mampu memprediksi dan menganalisis fenomena dinamika aliran fluida secara teliti. Program perhitungan CFD dipilih dalam penelitian ini karena selain akurat juga dapat memberikan visualisasi dengan baik. Penelitian ini bertujuan untuk memahami karakteristika perpindahan panas, massa dan momentum dari dinding rod bahan bakar ke pendingin secara visual, pada medan temperatur, medan tekanan, dan medan energi kinetika pendingin, sebagai fungsi dinamika aliran di dalam kanal, pada kondisi tunak dan transien. Analisis dinamika aliran pada kanal bahan bakar PWR berbasis CFD dilakukan dengan menggunakan sampel data reaktor PWR dengan daya 1000 MWe dengan susunan bahan bakar 17x17. Untuk menguji sensitivitas persamaan aliran yang sesuai dengan model aliran turbulen pada kanal bahan bakar dilakukan pemodelan dengan menggunakan persamaan k-omega (Ƙ-ω, k-epsilon (Ƙ-ε, dan Reynold stress model (RSM. Pada analisis sensitivitas aliran turbulen di dalam kanal digunakan model mesh hexahedral dengan memilih tiga geometri sel yang masing masing berukuran 0,5 mm; 0,2 mm dan 0,15 mm. Hasil analisis menunjukkan bahwa pada analisis kondisi tunak (steady state, terdapat hasil yang mirip pada model turbulen Ƙ-ε standard dan Ƙ-ω standard. Pengujian terhadap kriteria Dittus Boelter untuk bilangan Nusselt menunjukkan bahwa model Reynold stress model (RSM direkomendasikan. Analisis sensitivitas terhadap geometri mesh antara sel yang berukuran 0,5 mm, 0,2 mm dan 0,15 mm, menunjukkan bahwa geometri sel sebesar 0,5 mm telah mencukupi. Aliran turbulen berkembang penuh telah tercapai pada model LES dan DES, meskipun hanya dalam waktu singkat (3 s, model LES memerlukan waktu komputasi

  5. ANALISIS BAURAN PEMASARAN KENDARAAN RODA TIGA MEREK KAISAR PADA PT KAISAR MOTORINDO INDUSTRI PEKANBARU

    Directory of Open Access Journals (Sweden)

    Bambang Suroto

    2015-04-01

    Full Text Available Abstrak: Banyaknya perusahaan atau operator yang melayani jaringan internet secara otomatis akan timbul suatu proses yang dinamakan pemasaran. Di dalam dunia usaha, pemasaran merupakan salah satu fungsi penting didalam suatu perusahaan, karena dalam pemasaran mencakup beberapa hal kegiatan penting yang kita kenal dengan marketing mix yang diantaranya adalah perencanaan produk (product, penetapan harga (price, program promosi (promotion, sangat penting dalam keberhasilan suatu perusahaan namun ada satu hal yang perlu diperhatikan dan perlu dianalisis apabila perusahaan menginginkan atau mempunyai daur hidup atau life cycle produk yang lebih lama, maka perusahaan harus melakukan analisis perilaku pelanggan. Selain kegiatan pemasaran yang sangat penting perusahaan juga tidak boleh mengabaikan apa yang dibutuhkan oleh seorang konsumen, faktor apa saja yang dapat merangsang pelanggan untuk melakukan pembelian suatu barang, serta mengapa konsumen mempunyai banyak kebutuhan dalam waktu yang relatif singkat dan tentunya hal itu semua menggambarkan arti penting sebuah kegiatan analisis perilaku konsumen. Keluhan yang dirasakan konsumen atau pelanggan adalah promosi yang diberikan atau ditawarkan terkadang sering tidak sesuai dengan kenyataan yang ada di lapangan, seperti akses internet yang lama, dan jaringan yang sering terputus karena adanya gangguan dan sistem perbaikan jaringan. Masalah dalam penelitian ini adalah faktor-faktor apakah yang menyebabkan tidak tercapainya target pemasaran pemasangan jaringan internet speedy pada PT.Kaisar Motorindo Industri Pekanbaru. Metode yang digunakan dalam penelitian ini adalah dengan menggunakan metode deskriptif, yaitu menggunakan analisis data kualitatif serta analisis data dengan menghubungkan antara teori dan permasalahan yang diteliti. Hasil penelitian diperoleh variabel produk, dalam hal ini merupakan kombinasi barang dan jasa yang ditawarkan oleh perusahaan kepada pasar sasaran terhadap pemasaran jaringan

  6. Analisis pengaruh capital adequacy ratio (CAR) dan operational efficiency ratio (OER) terhadap return on assets (ROA) (Studi pada bank umum syariah devisa di Indonesia)

    OpenAIRE

    Maryadi, Eldi

    2017-01-01

    Tujuan dari penelitan ini adalah untuk menganalisis (1) perkembangan ROA, CAR dan OER pada bank umum syariah devisa di Indonesia. (2) CAR dan OER terhadap ROA pada bank umum syariah devisa di Indonesia periode 2009-2014. Data yang digunakan adalah data time series dari Laporan Keuangan tahunan Bank Umum Syariah Devisa di Indonesia periode 2009-2014, yaitu Bank BNI Syariah, Bank Mega Syariah, Bank Muamalat Indonesia, dan Bank Mandiri Syariah. Alat analisis yang digunakan adalah analisis deskri...

  7. ANALISIS KONDISI TERAS REAKTOR DAYA MAJU AP1000 PADA KECELAKAAN SMALL BREAK LOCA

    Directory of Open Access Journals (Sweden)

    Andi Sofrany Ekariansyah

    2015-06-01

    Full Text Available ABSTRAK ANALISIS KONDISI TERAS REAKTOR DAYA MAJU AP1000 PADA KECELAKAAN SMALL BREAK LOCA. Kecelakaan yang diakibatkan oleh kehilangan pendingin (loss of coolant accident / LOCA dari sistem reaktor merupakan kejadian dasar desain yang tetap diantisipasi dalam desain reaktor daya yang mengadopsi teknologi Generasi II hingga IV. LOCA ukuran kecil (small break LOCA memiliki dampak yang lebih signifikan terhadap keselamatan dibandingkan LOCA ukuran besar (large break LOCA seperti terlihat pada kejadian Three-Mile Island (TMI. Fokus makalah adalah pada analisis small break LOCA pada reaktor daya maju Generasi III+ yaitu AP1000 dengan mensimulasikan tiga kejadian pemicu yaitu membukanya katup Automatic Depressurization System (ADS secara tak disengaja, putusnya salah satu pipa Direct Vessel Injection (DVI secara double-ended, dan putusnya pipa lengan dingin dengan diameter bocoran 10 inci. Metode yang digunakan adalah simulasi kejadian pada model AP1000 yang dikembangkan secara mandiri menggunakan program perhitungan RELAP5/SCDAP/Mod3.4. Dampak yang ingin dilihat adalah kondisi teras selama terjadinya small break LOCA yang terdiri dari pembentukan mixture level dan transien temperatur kelongsong bahan bakar. Hasil simulasi menunjukkan bahwa mixture level untuk semua kejadian small break LOCA berada di atas tinggi teras aktif yang menunjukkan tidak terjadinya core uncovery. Adanya mixture level berpengaruh pada transien temperatur kelongsong yang menurun dan menunjukkan pendinginan bahan bakar yang efektif. Hasil di atas juga identik dengan hasil perhitungan program lain yaitu NOTRUMP. Keefektifan pendinginan teras juga disebabkan oleh berfungsinya injeksi pendingin melalui fitur keselamatan pasif yang menjadi ciri reaktor daya AP1000. Secara keseluruhan, hasil analisis menunjukkan model AP1000 yang telah dikembangkan dengan RELAP5 dapat digunakan untuk keperluan analisis kecelakaan dasar desain pada reaktor daya maju AP1000. Kata kunci: analisis

  8. Analisi comparativa della dieta di alcuni carnivori opportunisti (Vulpes vulpes, Martes foina, Meles meles in Europa

    Directory of Open Access Journals (Sweden)

    Anna Maria De Marinis

    2003-10-01

    Full Text Available L'ecologia alimentare della volpe, del tasso ed in misura minore della faina è stata ampiamente studiata in diverse aree comprese all'interno degli areali di queste 3 specie. La variazione geografica delle abitudini alimentari di questi carnivori definiti opportunisti è al contrario decisamente poco nota. Scopo del presente lavoro è la descrizione della variazione della dieta di faina, tasso e volpe attraverso l'Europa ed in secondo luogo l'analisi comparativa delle strategie alimentari adottate da questi carnivori. Sono stati analizzati 19 studi per la volpe, 11 per la faina e 23 per il tasso. Sono stati presi in considerazione soltanto gli studi della durata di almeno un anno nei quali la composizione della dieta, determinata tramite analisi delle feci, fosse espressa in percentuale di volume o biomassa e le categorie alimentari fossero dettagliatamente descritte. Gli studi sono stati divisi in gruppi in base alla regione climatica di appartenenza (mediterranea, centroeuropea, atlantica e boreale. Le categorie alimentari utilizzate nell'analisi della variabilità geografica sono: mammiferi, uccelli, anfibi, artropodi, lombrichi, altro animale, frutta, cereali, rifiuti. L'analisi delle componenti principali, condotta separatamente sulle 3 specie, ha consentito l'individuazione su di un grafico bidimensionale di due gruppi riferibili all'Europa centro-settentrionale ed alla regione mediterranea, con una percentuale di variabilità spiegata > 76% per ognuna delle 3 specie. La composizione della dieta del primo gruppo risulta caratterizzata da elevate percentuali di mammiferi e secondariamente uccelli per la volpe, uccelli ed altro animale per la faina e lombrichi, cereali ed anfibi per il tasso. La composizione della dieta nella regione mediterranea risulta invece caratterizzata da elevate percentuali di artropodi e frutta per tutte e 3 le specie di carnivori. L'analisi dicriminante ha consentito di differenziare gli studi condotti in ambiente

  9. Probabilistic analysis of safety in industrial irradiation plants; Analisis probabilistico de seguridad en plantas industriales de irradiacion

    Energy Technology Data Exchange (ETDEWEB)

    Alderete, F.; Elechosa, C. [Autoridad Regulatoria Nuclear, Av. del Libertador 8250 - Buenos Aires (Argentina)]. e-mail: falderet@sede.arn.gov.ar

    2006-07-01

    The Argentinean Nuclear Regulatory Authority is carrying out the Probabilistic Safety Analysis (PSA) of the two industrial irradiation plants existent in the country. The objective of this presentation is to show from the regulatory point of view, the advantages of applying this tool, as well as the appeared difficulties; for it will be made a brief description of the facilities, of the method and of the normative one. Both plants are multipurpose facilities classified as 'industrial irradiator category IV' (panoramic irradiator with source deposited in pool). Basically, the execution of an APS consists of the following stages: 1. Identification of initiating events. 2. Modeling of Accidental Sequences (Event Trees). 3. Analysis of Systems (Fault trees). 4. Quantification of Accidental Sequences. The argentine normative doesn't demand to these facilities the realization of an APS, however the basic standard of Radiological Safety establishes that in the design of this type of facilities in the cases that is justified, should make sure that the annual probability of occurrence of an accidental sequence and the resulting dose in a person gives as result an radiological risk inferior to the risk limit adopted as acceptance criteria. On the other hand the design standard specifies for these irradiators it demands a maximum fault rate of 10{sup -2} for the related components with the systems of radiological safety. In our case, the possible initiating events have been identified that carried out to not wanted situations (about people exposure, radioactive contamination). Then, for each one of the significant initiating events, the corresponding accidental sequences were modeled and the safety systems that intervene in this sequences by means of fault trees were analyzed, for then to determine the fault probabilities of the same ones. At the moment they are completing these fault trees, but the difficulty resides in the impossibility of obtaining real data

  10. ANALISIS VARIABEL KEUANGAN YANG MEMPENGARUHI KEBIJAKAN DEVIDEN

    Directory of Open Access Journals (Sweden)

    Sumiadji -

    2012-03-01

    Full Text Available Penelitian ini dilakukan untuk menguji pengaruh variabel keuangan yang terdiri dari: rasio pro-fitabilitas (return on assets, likuiditas (cash ratio, rasio hutang (debt to equity ratio, market value (earnings per share, dan perputaran total aset (total assets turnover terhadap kebijakan dividen yang diproksikan dengan dividend payout ratio (DPR pada perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia tahun 2004-2008. Prosedur pemilihan sampel penelitian menggunakan purposive sampling sehingga menghasilkan 8 perusahaan yang memenuhi kriteria sampel. Data sekunder dikumpulkan dengan teknik dokumentasi bersumber dari Indonesian Capital Market Directory (ICMD, laporan keuangan, dan hasil Rapat Umum Pemegang Saham (RUPS. Teknik analisis yang digunakan dalam penelitian ini adalah analisis regresi linear berganda. Hasil penelitian ini adalah secara simultan variabel ROA, CR, DER, EPS dan TATO berpengaruh terhadap DPR. Secara parsial variabel yang mempengaruhi DPR adalah CR, EPS dan TATO. Varabel lainnya, yaitu ROA dan DER ditemukan tidak berpengaruh terhadap DPR. This research was conducted to examine the influence of the financial variables which consists of: return on assets (ROA, cash ratio (CR, debt to equity ratio (DER, earnings per share (EPS, and total asset turnover (TATO to the dividend policy that indicated by the dividend payout ratio (DPR of listed manufacturing company in Indonesia Stock Exchange  2004 to 2008. The sample selection procedure used was a purposive sampling so that it produced eight companies that met the sample criteria. Se-condary data was collected by the documentation technique were obtained from the Indonesian Capital Market Directory (ICMD, financial statements, and the results of the Annual General Meeting of Shareholders. The analysis technique used was multiple linear regression analysis. The research found that five variables of kind of ROA, CR, DER, EPS dan TATO simultaneously influence to dividend

  11. Analisis Pengaruh Monetary Policy Shock Terhadap Jumlah Deposito Perbankan Islam Dalam Sistem Perbankan Ganda: Studi Kasus Indonesia Dan Malaysia

    Directory of Open Access Journals (Sweden)

    Ade Mutiah

    2014-03-01

    Full Text Available Tujuan dari penelitian ini adalah ingin menguji secara empiris, apakah perilaku nasabah perbankan Islam di Indonesia dan di Malaysia terpengaruh oleh kebijakan moneter yang dikeluarkan oleh bank sentral pada masingmasing negara. Selain itu, apakah negara dengan karakteristik ekonomi dan kebijakan yang hampir sama – Indonesia dan Malaysia -, akan menghasilkan perilaku nasabah terhadap deposito perbankan Islam yang sama atau tidak. Metode analisis yang digunakan dalam penelitian ini adalah yang pertama , metode ekonometrika VAR (Vector Auto Regression yang bila terjadi kointegrasi pada data yang stasioner di 1st difference akan dilanjutkan pada VECM (Vector Error Correction Models dan yang kedua, analisis elastisitas permintaan deposito perbankan Islam terhadap variabel-variabel yang diuji dalam penelitian ini pada periode Januari 2005 sampai dengan Desember 2009. Hasil dari penelitian ini menujukkan bahwa dalam jangka panjang variabel moneter di Indonesia berpengaruh secara signifikan terhadap deposito perbankan Islam. Berbeda dengan di Malaysia di mana variable moneter tidak berpengaruh secara signifikan terhadap deposito perbankan Islam. Begitupun hasil analisis elastisitas permintaan deposito perbankan Islam di kedua negara. Dengan demikian dapat disimpulkan bahwa deposito perbankan Islam di Indonesia lebih sensitif terhadap perubahan kebijakan moneter, dibandingkan dengan yang ada di Malaysia.JEL Classifications : E41, E52, G21.Keywords : Kebijakan Moneter; Deposito; Perbankan Islam; VECM; Elastisitas.

  12. Analisis Highest and Best Use (HBU pada Lahan Jl. Gubeng Raya No. 54 Surabaya

    Directory of Open Access Journals (Sweden)

    Akmaluddin Akmaluddin

    2013-03-01

    Full Text Available Laju pertumbuhan penduduk dan tingkat perekonomian yang semakin meningkat di  kota-kota besar seperti Surabaya, bertolak belakang dengan  ketersediaan lahan yang terbatas. Selayaknya properti yang akan dibangun di atas suatu lahan dapat memberikan manfaat yang maksimal serta efisien agar hasilnya dapat dirasakan demi pembangunan wilayah tersebut. Oleh karena itu, perlu dilakukan perhitungan  penggunaan yang paling memungkinkan dan diizinkan dari suatu tanah kosong atau tanah yang  sudah dibangun, dimana secara fisik dimungkinkan, didukung atau dibenarkan oleh peraturan, layak secara keuangan dan menghasilkan nilai tertinggi. Dalam penelitian ini dilakukan analisis Highest and Best Use (HBU pada lahan di Jl. Gubeng Raya No. 54 Surabaya seluas 1.150 m2 yang direncanakan akan dibangun hotel. Lahan tersebut berpotensi untuk dikembangkan menjadi properti komersial seperti hotel, apartemen, perkantoran dan pertokoan. Analisis tersebut menggunakan tinjauan terhadap aspek fisik, legal, finansial dan produktivitas maksimumnya. Dari hasil penelitian ini didapatkan alternatif properti komersial hotel yang memiliki penggunaan tertinggi dan terbaik pada pemanfaatan lahan dengan nilai lahan Rp. 67.069.980,31/ m2.

  13. ANALISIS SUMBER-SUMBER KEBERMAKNAAN HIDUP NARAPIDANA YANG MENJALANI HUKUMAN SEUMUR HIDUP

    Directory of Open Access Journals (Sweden)

    Siska Marliana

    2012-04-01

    Full Text Available Narapidana yang mendapat hukuman seumur hidup akan mengalami perubahan besar dalam kehidupannya, seperti keterbatasan dalam melakukan aktivitas, pekerjaan, kehidupan sosial bahkan dalam tujuan hidup. Kondisi tersebut akan  mengubah pandangannya mengenai makna dari hidupnya ataupun mengalami ketidakbermaknaan hidup. Fokus penelitian ini adalah analisis sumber-sumber kebermaknaan hidup pada narapidana yang divonis hukuman seumur hidup dengan mengacu pada konsep kebermaknaan hidup Viktor Frankl. Penelitian ini merupakan penelitian kualitatif dengan pendekatan studi kasus pada seorang narapidana di Lembaga Pemasyarakatan Klas 1 Sukamiskin Bandung yang sudah menjalani dua tahun masa hukuman dari vonis hukuman seumur hidup atas kasus pembunuhan. Teknik pengambilan data dilakukan dengan wawancara, observasi dan analisis dokumen. Hasil penelitian ini menunjukkan bahwa sumber-sumber kebermaknaan hidup bagi subjek adalah : 1.  Adanya nilai-nilai kreatif (creative values untuk dapat berkarya, bekerja, mencipta serta melaksanakan tugas dan kewajiban sebaik-baiknya. 2. Adanya nilai-nilai penghayatan (experiential values, yakni dengan cara memperoleh pengalaman tentang sesuatu atau seseorang yang bernilai bagi subjek. 3. Nilai-nilai bersikap (attitudinal values atas hukuman seumur hidup yaitu subjek memilih sikap menerima kondisi tersebut sebagai tanggung jawab yang harus dijalani akibat perbuatannya dan berusaha menikmati kehidupan di penjara dengan menjadikan penjara sebagai tempat untuk belajar menjadi manusia yang lebih baik. Kata Kunci: hukuman seumur hidup, sumber-sumber kebermaknaan hidup, creative values, experiential values, attitudinal values

  14. Recycling of sewage sludge: Feeding Nile tilapia, Oreochromis niloticus (Linn.), with irradiated and dried sludge from beer industry

    International Nuclear Information System (INIS)

    Chuapoehuk, W.; Piadang, S.; Tinnungwattana, W.

    1998-01-01

    Recycling of sewage sludge from wastewater treatment plant of beer industry as supplemental feed for fish was conducted. Industrial biosludge from wastewater treatment plant of beer industry was irradiated at 3.32 kGy gamma irradiator, carrier type, model JS 8900, 60 Co activity at 187,088.121 Ci on 6 June 1995. For fish production study, it is needed to change the wet sludge to dry powder form by Rotadics dryer, type Stord TST 3.4 C, Stord (Thailand) Co. Ltd., at the maximum capacity of 15 T/24 h. The moisture content of finished product is at 8-10%. Fish control diet was then replaced at 60% by weight with irradiated and dried sludge to become as test diet. Nile tilapia, Oreochromis niloticus (Linn.), fingerlings averaging 0.67 g. in body weight was stocked into earthern ponds of 400 square meters at the density of 5 fishes per square metre. Fish were fed with two diets, control diet and test diet, for 154 days. There are no statistical differences in specific growth rate, quality of the fish flesh (Cd and Pb concentration, edible portion and off flavour) and pond water quality. Survival rate and feed conversion efficiency of the fish fed test diet are higher than control diet (P<0.05). Replacement of irradiated sludge can decrease the cost of fish production and results in better benefit than that of control diet

  15. ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KEPUASAN KONSUMEN BERBELANJA ONLINE DI PROVINSI PULAU JAWA

    Directory of Open Access Journals (Sweden)

    Januar Israhmawan Putra

    2017-11-01

    Full Text Available Penggunaan internet di Indonesia yang tumbuh dengan pesat diikuti dengan banyak ber - munculan situs e-commerce yang merubah budaya dan gaya berbelanja masyarakat menjadi serba online. Pertumbuhan pasar e-commerce ini harus dibarengi dengan pelayanan yang akan diberikan kepada konsumennya secara baik agar konsumen merasa puas ketika bertran - saksi kepada perusahaan. Tujuan penelitian ini yaitu untuk mengetahui faktor apa saja yang mempengaruhi kepuasan konsumen berbelanja online pada situs jual beli Lazada, Zalora, dan Mataharimall. Variabel independent yang digunakan dalam penelitian ini yaitu Website Design, Security, Information Quality, Payment Method, E-service Quality, Product Quality, Product Variety, Delivery Service dan variebel dependent adalah Customer Satisfaction. �e- �e- �e - sponden dalam penelitian ini adalah konsumen Lazada, Zalora, dan Mataharimall yang be - rada di wilayah Provinsi Jawa Barat, Jawa Tengah, dan Jawa Timur dengan jumlah responden sebanyak 400 orang. Teknik sampling yang digunakan adalah nonprobability sampling yaitu porposive sampling. Penelitian ini menggunakan metode kuantitatif dengan teknik analisis data regresi berganda dan teknik analisis deskriptif. Hasil peneltian ini menunjukan bahwa website design, information quality, product vaiety, delivery service berpengaruh signifikan terhadap kepuasan konsumen dalam berbelanja online.

  16. Irradiation of bovine meat: effect of heme-iron concentration.; Irradiacao de carne bovina: efeito na concentracao de ferro heme

    Energy Technology Data Exchange (ETDEWEB)

    Mistura, Liliana Perazzini Furtado

    2002-07-01

    The irradiation is often used, nowadays, for meat conservation and it is important to know how much this process interferes with the nutritional quality of the meat. In this study round cut meat, ground and steaks (from a local supermarket) was irradiated with doses of O; 1; 2; 3; 4; 5; 7,5 and 10 kGy (JS-7500 Nordium Inc -Canada) and the interference of irradiation and the process of food preparation on heme-iron (H Fe) content was determined. Half of the sample was kept raw and the other half was grilled in a pre-warmed oven at 250 deg C for 9 min and a controlled humidity of 70%. The chemical composition, the total iron (T Fe) (EM) and the heme iron concentration were determined (Hornsey,1956) and the sensorial quality evaluated. The average T Fe concentration of raw and ground , ground and grilled, raw steaks and grilled steak meat, on dry and degreased basis was 113 mug/g, 121 mug/g , 91 mug/g and 77 mug/g; and the H Fe concentration 105 mug/g (93% of T Fe) , 88 mug/g (73% of T Fe), 90 mug/g (99% of T Fe) and 52 mug/g (68% of T Fe) respectively. Data were evaluated by ANOVA with fixed effects and multiple comparisons. The irradiation neither altered the chemical composition nor the proportion of heme iron of meat. The preparation conditions (temperature, cooking time, environment humidity, meat presentation) of the sample interfered more with the heme iron content than the irradiation. With the sensorial analysis we verified that meats irradiated with doses of 3 kGy were better evaluated in softness and succulency attributes than the others. Meat submitted to irradiation doses up to 3 kGy were accepted by the specialists' panel. (author)

  17. FeatureViewer, a BioJS component for visualization of position-based annotations in protein sequences [v1; ref status: indexed, http://f1000r.es/2u2

    Directory of Open Access Journals (Sweden)

    Leyla Garcia

    2014-02-01

    Full Text Available Summary: FeatureViewer is a BioJS component that lays out, maps, orients, and renders position-based annotations for protein sequences. This component is highly flexible and customizable, allowing the presentation of annotations by rows, all centered, or distributed in non-overlapping tracks. It uses either lines or shapes for sites and rectangles for regions. The result is a powerful visualization tool that can be easily integrated into web applications as well as documents as it provides an export-to-image functionality. Availability: https://github.com/biojs/biojs/blob/master/src/main/javascript/Biojs.FeatureViewer.js; http://dx.doi.org/10.5281/zenodo.7719

  18. ANALISIS STRUKTUR AKTANSIAL DAN FUNGSIONAL DALAM VOYAGE AUCENTREDELA TERRE KARYA JULES VERNE

    OpenAIRE

    Ade Yolanda Latjuba, Dr. M.A

    2017-01-01

    Berdasarkan hasil analisis, maka dapat disimpulkan sebagai berikut: 1. Roman Voyage au centre de la terre menceritakan tentang Prof. Lidenbrock, Axel, dan Hans Bjelke melakukan perjalanan luar biasa menuju pusat bumi berdasarkan petunjuk dari Ame Saknussemm yang Axel dan si Professor dapatkan secara tidak sengaja terselip di dalam sebuah buku tua karya Snorre Tarlesson. 2. Prof. Lidenbrock, Axel dan Hans Bjelke memulai perjalanan mereka menuju pusat bumi dengan cara menuruni gunung bera...

  19. ANALISIS SEGMENTASI PASAR PRODUK YOGHURT BERDASARKAN PERILAKU KONSUMEN PADA HYPERMART CABANG PANAKUKANG, MAKASSAR

    OpenAIRE

    -, ANDRIANI

    2014-01-01

    2014 v ABSTRAK Andriani. I311 04 049. Analisis Segmentasi Pasar Berdasarkan Perilaku Konsumen pada Hypermart Cabang Panakukang, Makassar. Dibawah Bimbingan Ir. Hastang, M.Si sebagai Pembimbing Utama dan Muh. Ridwan, S.Pt, M.Si. sebagai Pembimbing Anggota. Perkembangan dan peningkatan bisnis khususnya pada usaha peternakan akhir-akhir ini menunjukkan banyak peningkatan. Salah satu strategi yang dapat diterapkan dalam menunjang aktivitas pemasaran oleh perusahaan dalam memasarkan pr...

  20. ANALISIS PENERAPAN TAX PLANNING ATAS PAJAK PENGHASILAN BADAN PADA PT SEMEN TONASA PANGKEP

    OpenAIRE

    WIJAYA, AKBAR

    2014-01-01

    2014 ABSTRAK ANALISIS PENERAPAN TAX PLANNING ATAS PAJAK PENGHASILAN BADAN PADA PT SEMEN TONASA PANGKEP Implementation Analysis of Tax Planning on Board Incoming Tax of Semen Tonasa Ltd. Pangkep Akbar Wijaya Amiruddin Darmawati Penelitian ini bertujuan untuk mengetahui tax planning yang dilakukan oleh PT Semen Tonasa Pangkep, dan untuk menganalisis penerapan tax planning yang dilakukan oleh PT Semen Tonasa Pangkep dengan undang-undang perpajakan yang berlaku. Data...

  1. Letter regarding Li JS et al. entitled "ERCC polymorphisms and prognosis of patients with osteosarcoma".

    Science.gov (United States)

    Jian, Yuekui; Tian, Xiaobin; Li, Bo; Zhou, Zhuojia; Wu, Xinglin

    2015-05-01

    With great interest, we read the article "ERCC polymorphisms and prognosis of patients with osteosarcoma" (by Li JS et al.), which has reached important conclusions about the relationship between ERCC polymorphisms and osteosarcoma prognosis. Through quantitative analysis, the meta-analysis showed that ERCC2 Lys751Gln (ORGG vs. AA = 0.40 (95%CI = 0.1-0.86), P heterogeneity = 0.502; I (2) = 0 %) and ERCC5 His46His (ORCC vs. TT = 0.37 (95%CI = 0.15-0.93), P heterogeneity = 0.569; I (2) = 0 %) polymorphisms might influence the prognosis of patients with osteosarcoma [1]. The meta-analysis results are encouraging. Nevertheless, some deficiencies still existed that we would like to raise.

  2. Pengembangan Tungku Gasifikasi Arang Biomassa Tipe Natural Draft Gasification Berdasarkan Analisis Computational Fluid Dynamics (CFD

    Directory of Open Access Journals (Sweden)

    Erlanda Augupta Pane

    2014-10-01

    Full Text Available A biomass stove based on natural draft gasification (NDG has been developed in a previous study (Nelwa, et al. 2013 by using simulation based on heat transfer and equilibrium modeling. In this study, a CFD simulation was performed in order to analyze the effect of chimney height, and inlet hole diameter of the stove to the performance of the stove. The results of simulation showed that power produced by stove was between 1863.9 J/s until 2585.7 J/s, and its gasification efficiency was 67.11%. The results of simulation also showed that charcoal gasification produces combustible gases (CO, CH4, and H2 at the bottom and the center of stove, and then they were oxidized by secondary air at the top of stove. This oxidation reaction produces sufficient heat energy which can be used for cooking process.

  3. Analisi sui pigmenti di ceramica neolitica tramite tecniche Raman e LIBS

    Directory of Open Access Journals (Sweden)

    Cristina Fabbri

    2007-04-01

    Full Text Available I dati presentati in questo breve contributo provengono da uno studio condotto in collaborazione dal Dipartimento di Scienze Archeologiche dell’Università di Pisa e dall’Istituto per i Processi Chimico-Fisici di Fisica molecolare del CNR di Pisa. Le metodologie applicate sono basate sull’analisi integrata delle tecniche spettroscopiche Raman e LIBS già ampiamente utilizzate nel campo dei Beni Culturali; i metodi sono infatti essenzialmente non distruttivi, non richiedono di un pre trattamento del campione e l’acquisizione delle misure è immediata.

  4. Historical-statistical analysis of energy consumption in energy management; Analisis historico-estadistico del consumo energetico en la administracion de energia

    Energy Technology Data Exchange (ETDEWEB)

    Guizar Bejarano, Ruben [IMENOR (Mexico); Oven, Mark [RCG/Hagler, Bailly, Inc., Washington (United States)

    1993-12-31

    Traditionally the specific consumption of energy has been considered as the most adequate index to evaluate the efficiencies in the productive processes. Nevertheless, this index, in some instances is highly susceptible to suffer significant variations, due to factors such as equipment condition, raw materials quality, operational parameters, climate and production level. This last one definitely is the most important and requires a deeper analysis. In this presentation a methodology is developed to analyze the energy consumption as well as their specific energy consumption with respect to production. Enough historical data are utilized to allow for a statistical analysis. This study is of equal usefulness in an energy diagnosis, as in a management program of energy saving. In presenting the possibility of identifying potential energy saving, stands out the advantages of the analysis and the conclusions that can be derived from it. Through the actual data collected in several industries during the energy diagnosis, various possible results of the analysis are presented. Finally, how this type of analysis can be adapted to a more precise control of the energy consumption is described and be used as a base for establishing goals in energy efficiency in the long term. [Espanol] Tradicionalmente se ha considerado al consumo especifico de energia como el indice energetico mas adecuado para evaluar las eficiencias de los procesos productivos. Sin embargo, este indice es en ocasiones altamente susceptible a sufrir variaciones importantes, debido a factores como el estado de los equipos, la calidad de la materia prima, los parametros operativos, el clima, y el nivel de produccion. Este ultimo es decididamente el mas importante, y requiere un analisis mas profundo. En esta presentacion se desarrolla una metodologia para analizar tanto consumos de energia como consumos especificos de energia con respecto a la produccion. Se utilizan suficientes datos historicos para permitir

  5. Historical-statistical analysis of energy consumption in energy management; Analisis historico-estadistico del consumo energetico en la administracion de energia

    Energy Technology Data Exchange (ETDEWEB)

    Guizar Bejarano, Ruben [IMENOR (Mexico); Oven, Mark [RCG/Hagler, Bailly, Inc., Washington (United States)

    1992-12-31

    Traditionally the specific consumption of energy has been considered as the most adequate index to evaluate the efficiencies in the productive processes. Nevertheless, this index, in some instances is highly susceptible to suffer significant variations, due to factors such as equipment condition, raw materials quality, operational parameters, climate and production level. This last one definitely is the most important and requires a deeper analysis. In this presentation a methodology is developed to analyze the energy consumption as well as their specific energy consumption with respect to production. Enough historical data are utilized to allow for a statistical analysis. This study is of equal usefulness in an energy diagnosis, as in a management program of energy saving. In presenting the possibility of identifying potential energy saving, stands out the advantages of the analysis and the conclusions that can be derived from it. Through the actual data collected in several industries during the energy diagnosis, various possible results of the analysis are presented. Finally, how this type of analysis can be adapted to a more precise control of the energy consumption is described and be used as a base for establishing goals in energy efficiency in the long term. [Espanol] Tradicionalmente se ha considerado al consumo especifico de energia como el indice energetico mas adecuado para evaluar las eficiencias de los procesos productivos. Sin embargo, este indice es en ocasiones altamente susceptible a sufrir variaciones importantes, debido a factores como el estado de los equipos, la calidad de la materia prima, los parametros operativos, el clima, y el nivel de produccion. Este ultimo es decididamente el mas importante, y requiere un analisis mas profundo. En esta presentacion se desarrolla una metodologia para analizar tanto consumos de energia como consumos especificos de energia con respecto a la produccion. Se utilizan suficientes datos historicos para permitir

  6. CerebralWeb: a Cytoscape.js plug-in to visualize networks stratified by subcellular localization.

    Science.gov (United States)

    Frias, Silvia; Bryan, Kenneth; Brinkman, Fiona S L; Lynn, David J

    2015-01-01

    CerebralWeb is a light-weight JavaScript plug-in that extends Cytoscape.js to enable fast and interactive visualization of molecular interaction networks stratified based on subcellular localization or other user-supplied annotation. The application is designed to be easily integrated into any website and is configurable to support customized network visualization. CerebralWeb also supports the automatic retrieval of Cerebral-compatible localizations for human, mouse and bovine genes via a web service and enables the automated parsing of Cytoscape compatible XGMML network files. CerebralWeb currently supports embedded network visualization on the InnateDB (www.innatedb.com) and Allergy and Asthma Portal (allergen.innatedb.com) database and analysis resources. Database tool URL: http://www.innatedb.com/CerebralWeb © The Author(s) 2015. Published by Oxford University Press.

  7. Analisis Biaya, Volume, Laba sebagai Alat Bantu Perencanaan Laba pada Hotel Sedona Manado

    OpenAIRE

    Samahati, Ricky Budiman

    2013-01-01

    Manado sebagai kota pariwisata menyediakan sarana dan prasarana kepariwisataan termasuk jasa perhotelan. Hotel Sedona merupakan salah satu hotel yang ada di Kota Manado dan merupakan objek yang dipilih penulis dengan menggunakan data operasional penjualan yang terjadi pada tahun 2011 dan 2012. Tujuan penelitian ini yaitu untuk mengetahui titik break even point, jumlah volume penjualan pada tingkat laba yang direncanakan, serta tingkat margin of safety pada Hotel Sedona Manado. Metode analisi...

  8. ANALISIS POTENSI PEMUNGUTAN PAJAK HOTEL DALAM RANGKA PENINGKATAN PENDAPATAN ASLI DAERAH KOTA MAKASSAR

    OpenAIRE

    -, MUHAMMAD TRY DHARSANA AMBO ALA DEPARTEMEN AKUNTANSI FAKULTAS EKONOMI DAN BISNIS UNIVERSITAS HASANUDDIN MAKASSAR 2017

    2017-01-01

    Analisis Potensi Pemungutan Pajak Hotel dalam Rangka Peningkatan Pendapatan Asli Daerah Kota Makassar Analysis of Hotels Tax Collection Potency in Makkasar???s Own-Source Revenue Increase Muhammad Try Dharsana Ambo Ala Andi Kusumawati Yulianus Sampe Tujuan penelitian ini adalah untuk mengetahui besar potensi pajak hotel dan seberapa jauh bentuk usaha yang di lakukan oleh pemerintah daerah dalam menggali potensi pajak hotel di kota Makassar. Untuk menghitung potensi, efektivi...

  9. Analisis Juridis Pelaksanaan Penghapusan Piutang Terhadap Kredit Macet (Studi Pada PT. Bank Sumut)

    OpenAIRE

    Margareth Eka Purba

    2009-01-01

    Usaha pokok Bank adalah sektor perkreditan dan pendapatan bank yang terbesar adalah berasal dari sektor perkreditan. Kredit, baik konsumtif maupun produktif memang sudah mejadi target utama perbankan dalam meraih pendapatan, selain fee based income tentunya. Dengan demikian, kelebihan dana masyarakat yang bisa membuat bank memiliki dana idle yang akan lebih produktif lagi karena diberikan dalam bentuk kredit.Walaupun sudah dilakukan analisis kredit, dan kredit sudah dinyatakan layak untuk dib...

  10. Perangkat Lunak Untuk Analisis Gaya Gelombang Di Laboratorium Lingkungan Dan Energi Laut, Jurusan Teknik Kelautan, Ftk-Its

    Directory of Open Access Journals (Sweden)

    Fendi Hidayat

    2013-09-01

    Full Text Available Laboratorium Lingkungan dan Energi Laut, Jurusan Teknik Kelautan, FTK-ITS sering digunakan untuk pengujian. Salah satunya menguji gaya mooring pada floating breakwater. Hal tersebut menjadi salah satu alasan untuk membuat suatu perangkat lunak dalam membantu dalam proses analisis gaya mooring tersebut. Perangkat lunak yang dibuat berfungsi untuk membantu proses kalibrasi sensor load cell LUB-B 5 to 50 KB dan melakukan analisis gaya gelombang. Metode yang digunakan dalam penelitian ini adalah dengan menggunakan regresi linier, korelasi linier, perhitungan varian, standar deviasi, dan hukum Newton yang kemudian disusun dengan menggunakan Microsoft Visual Studio 2008. Penyusunan perangkat lunak yang bernama FORYS ini memiliki tampilan antarmuka pengguna yang mudah dalam pemakaian. Perangkat lunak yang telah dibuat juga bersifat portable sehingga bisa digunakan di berbagai komputer atau laptop. Hasil pengujian yang telah dilakukan menghasilkan bahwa semakin besar gaya gelombang yang terjadi, maka semakin besar pula tegangan yang terjadi pada tali.  

  11. EKSLUSI DAN INKLUSI PADA RUBRIK METROPOLITAN HARIAN KOMPAS: ANALISIS WACANA KRITIS BERDASARKAN SUDUT PANDANG THEO VAN LEEUWEN

    Directory of Open Access Journals (Sweden)

    Harry Andheska

    2015-10-01

    Full Text Available Penggunaan teori kritis sebagai alat pengkajian dalam penelitian ini disebabkan oleh adanya persoalan tentang penumpang kereta rel listrik (KRL yang sering melanggar aturan dengan menaiki atap kereta tersebut. Penelitian ini pada dasarnya lebih menekankan titik perhatiannya pada sosok penumpang KRL sebagai sosok yang senantiasa termajinalkan dalam kehidupan sosial. Kajian ini merupakan pendekatan kualitatif dengan metode analisis isi. Kajian ini juga terbatas hanya pada satu teks berita yang dimuat dalam satu rubrik metropolitan pada haian Kompas. Model analisis wacana yang digunakan adalah model Theo Van Leuween dengan tujuan untuk mendeteksi dan meneliti bagaimana para penumpang yang duduk di atap KRL dimarjinalkan posisinya dalam suatu wacana. Hasil penelitian ditemukan bahwa terdapat dua jenis eksklusi yang dilakukan, yakni pasivasi dan nominalisasi; sedangkan inklusi ada tiga jenis, yakni diferensiasi, abstraksi, dan identifikasi. Keterbatasan dalam kajian ini disebabkan karena faktor kajian yang hanya terfokus pada satu teks berita.

  12. STUDI PERBANDINGAN ANALISIS UNSUR PLUMBUM (PB DARI HASIL ELEKTROLISIS ANTARA METODE LASER- INDUCED BREAKDOWN SPECTROSCOPY (LIBS DENGAN METODE KONVENSIONAL

    Directory of Open Access Journals (Sweden)

    H. S. Suyanto

    2014-07-01

    Full Text Available Penelitian ini bertujuan menganalisis unsur Pb hasil proses elektrolisis dengan metode alternatif laser-induced breakdown spectroscopy (LIBS dan metode konvensional. Elektrolisis menggunakan tembaga (Cu sebagai katoda dan karbon sebagai anoda. Unsur Pb yang terdeposisi pada katoda diirradiasi laser Nd-YAG (model CFR 200, 1064nm dan emisinya (Pb I 405.7 nm ditangkap spektrometer HR 2500++ yang kemudian ditampilkan dalam intensitas fungsi panjang gelombang. Hasil penelitian menunjukkan bahwa energi laser, arus listrik dan waktu deposisi proses elektrolisis yang optimum untuk karakterisasi unsur Pb masing - masing adalah 100 mJ, 5,28 mA dan 15 menit. Aplikasi metode ini untuk analisis kuantitatif larutan Pb dengan membuat kurva kalibrasi dari kosentrasi 300 ppm sampai kosentrasi terendah yaitu 0,5 ppm, serta diperoleh deteksi limit sebesar 0,44 ppm. Sebagai perbandingan metode deteksi dengan LIBS ini telah dilakukan analisis dengan metode konvensional dengan menentukan selisih massa katoda sebelum dan sesudah elektrolisis dan diperoleh hasil yang sebanding.ABSTRACTThe aim of this research was to compare between a method of laser-induced breakdown spectroscopy (LIBS and the conventional one to analyse of Plumbum (Pb element resulted from electrolysis process. Electrolysis used copper (Cu and carbon (C as cathode and anode respectively. Plumbum element which was deposited on cathode was irradiated by Nd-YAG laser (model CFR 200, 1064nm and its emission intensity of neutral Pb I 405.7 nm in the plasma was captured by HR 2500++ spectrometer and displayed in a form of intensity as a function of wavelength. The experiment result showed that the optimum condition parameters of electrolysis: laser energy, electric current and electrolysis time duration were 100 mJ, 5.28 mA and 15 minutes respectively. An application of these conditions was done to make calibration curve of Pb element in liquid sample from 300 ppm to 0.5 ppm and resulted a limit of

  13. Analisis Pengaruh Kinerja Keuangan terhadap Alokasi Belanja Modal di Provinsi Jambi

    Directory of Open Access Journals (Sweden)

    Eko Indra Praza

    2016-09-01

    Full Text Available Abstract. This research aimed to analyze the financial performance of the District/ Municipality in Jambi Province and to determine the effect of financial performance either simultaneously or partially on capital expenditure. The data used in this research is a panel data comprising time series data is data in 2010 - 2013 and cross section data is data of 9 (nine District and 2 (two Municipality is located in the Province of Jambi. The analytical method used panel data regression analysis. The analysis showed that the financial performance of the District/ Municipality in Jambi Province is still relatively low as the PAD contribution to regional revenue is still small so transfer income still dominate the local revenue to finance most of the regional expenditure. The results of panel data regression using the Fixed Effect Model (FEM showed that the financial performance simultaneously significant effect on capital expenditure allocation of the District/Municipality in Jambi Province from 2010 to 2013 and partially Ratio Degree of Decentralization significant positive effect on the allocation of capital expenditure. Financial dependency ratio, Financial Independence Ratio and the ratio degrees contributions public enterprises significant negative effect on capital expenditure . Effectiveness ratio of PAD does not significantly influence the allocation of capital expenditure. Keyword: Financial Performance, Decentralization, Financial Independence,   Abstrak. Penelitian ini bertujuan untuk menganalisis kinerja keuangan Pemerintah Kabupaten/Kota di Provinsi Jambi dan untuk mengetahui pengaruh kinerja keuangan baik secara simultan maupun secara parsial terhadap alokasi belanja modal. Data yang digunakan dalam penelitian ini merupakan data panel yang terdiri dari data time series yaitu data tahun 2010 – tahun 2013 dan data cross section yaitu data 9 (sembilan Kabupaten dan 2 (dua Kota yang berada di Provinsi Jambi. Metode analisis yaitu analisis

  14. Analisis Daya Saing untuk Meningkatkan Kualitas Layanan terhadap Pelanggan dengan Pendekatan CRM di CV. BLITZSPOT

    Directory of Open Access Journals (Sweden)

    Suryadi Muhammad

    2017-04-01

    Full Text Available CV. Blitzspot adalah perusahaan yang bergerak di bidang jasa penyediaan layanan internet (internet service provider, yang berkantor pusat di Komplek Padasuka Indah Ruko Blok A-1, Cimahi, Jawa Barat. Berdasarkan hasil wawancara dan hasil observasi pada data transaksi CV. Blitzspot, konsumen CV. Blitzspot yang melakukan transaksi tiap tahunnya selalu berkurang, hal ini dikarenakan konsumen sering membandingkan layanan-layanan yang ditawarkan oleh para pesaing CV. Blitzspot. Bila permasalahan tersebut belum teratasi, konsumen CV. Blitzspot akan menurun tiap tahunnya dan akan selalu berpindah ke pesaing CV. Blitzspot. Direktur Utama CV. Blitzspot ingin menganalisis daya saing untuk menentukan layanan-layanan yang akan diberikan kepada pelanggan CV. Blitzspot dan penentuan strategi untuk mempertahankan konsumen CV. Blitzspot.  Metode Analisis daya saing yang digunakan adalah Model Analisis Berlian Porter dan Metode Pengelompokkan Pelanggan yang digunakan adalah Metode LRFM. Berdasarkan hasil pengujian dan pembahasan yang telah dibuat, maka dapat ditarik kesimpulan bahwa Direktur Utama dapat menganalisis daya saing CV. Blitzspot dengan menggunakan Berlian Porter untuk meningkatkan kualitas layanan terhadap pelanggan CV. Blitzspot.

  15. ANALISIS PENGUNGKAPAN SUSTAINABILITY REPORT PADA PERUSAHAAN NON-KEUANGAN TAHUN 2009-2013

    Directory of Open Access Journals (Sweden)

    Candri Puspita Marwati

    2015-10-01

    Full Text Available Penelitian ini bertujuan untuk menguji dan menganalisis pengaruh return on asset (ROA, likuiditas (current ratio, ukuran perusahaan (size, earning per share (EPS terhadap pengungkapan sustainability report. Sampel yang digunakan adalah perusahaan non-keuangan terdaftar di Bursa Efek Indonesia (BEI yang menerbitkan sustainability report sesuai standar GRI pada periode 2009-2013 dan diperoleh 12 perusahaan. Teknik analisis data menggunakan uji asumsi klasik: normalitas, multikolinearitas, autokorelasi dan heterokedastisitas. Uji hipotesis menggunakan analisis regresi berganda. Hasil penelitian ini menunjukkan bahwa ROA berpengaruh positif signifikan terhadap sustainability report, current ratio tidak mempengaruhi sustainability report, size memiliki pengaruh negatif dan signifikan terhadap sustainability report, dan EPS memiliki pengaruh negatif dan signifikan terhadap sustainability report.This study aims to examine and analyze the effect of return on assets (ROA, liquidity (current ratio, firm size (size, earnings per share (EPS on the disclosure of sustainability report. Sample are corporate non-financial listed on the Indonesia Stock Exchange (IDX and publishes a sustainability report according to GRI standard in the period 2009-2013 and obtained sample of 12 companies. Data were analyzed using classic assumption test: normality, multicollinearity, autocorrelation and heterokedastisitas. Hypothesis testing using multiple regression analysis. The results showed that, ROA significant positive effect on sustainability report. current ratio does not affect the sustainability report. size has a negative and significant impact on the sustainability report, and EPS has a negative and significant impact on the sustainability report.

  16. 3D Planetary Data Visualization with CesiumJS

    Science.gov (United States)

    Larsen, K. W.; DeWolfe, A. W.; Nguyen, D.; Sanchez, F.; Lindholm, D. M.

    2017-12-01

    Complex spacecraft orbits and multi-instrument observations can be challenging to visualize with traditional 2D plots. To facilitate the exploration of planetary science data, we have developed a set of web-based interactive 3D visualizations for the MAVEN and MMS missions using the free CesiumJS library. The Mars Atmospheric and Volatile Evolution (MAVEN) mission has been collecting data at Mars since September 2014. The MAVEN3D project allows playback of one day's orbit at a time, displaying the spacecraft's position and orientation. Selected science data sets can be overplotted on the orbit track, including vectors for magnetic field and ion flow velocities. We also provide an overlay the M-GITM model on the planet itself. MAVEN3D is available at the MAVEN public website at: https://lasp.colorado.edu/maven/sdc/public/pages/maven3d/ The Magnetospheric MultiScale Mission (MMS) consists of one hundred instruments on four spacecraft flying in formation around Earth, investigating the interactions between the solar wind and Earth's magnetic field. While the highest temporal resolution data isn't received and processed until later, continuous daily observations of the particle and field environments are made available as soon as they are received. Traditional `quick-look' static plots have long been the first interaction with data from a mission of this nature. Our new 3D Quicklook viewer allows data from all four spacecraft to be viewed in an interactive web application as soon as the data is ingested into the MMS Science Data Center, less than one day after collection, in order to better help identify scientifically interesting data.

  17. Analisis Kelayakan Finansial Usaha Budidaya Bambu

    Directory of Open Access Journals (Sweden)

    Husnul Khotimah

    2015-12-01

    Full Text Available Budidaya bambu diperlukan untuk menambah populasi bambu yang cenderung berkurang yang disebabkan oleh beralihnya fungsi lahan yang digunakan untuk pemukiman atau diganti dengan komoditi tanaman lain yang dianggap lebih menguntungkan. Sementara itu kebutuhan bahan baku bambu terus meningkat sejalan dengan pertumbuhan penduduk dan perkembangan kemajuan ilmu pengetahuan. Budidaya bambu bermanfaat selain untuk menjaga ketersediaan suplai juga untuk meningkatkan kualitas bambu untuk memenuhi permintaan pasar. Tulisan ini mengkaji analisis finansial dari penanaman bambu. Kajian finansial dibutuhkan untuk menunjukkan bahwa upaya penanaman atau budidaya bambu ini layak atau tidak secara finansial untuk dilakukan. Data yang digunakan adalah data hasil penelitian di perusahaan perkebunan bambu PT XYZ di Lampung. Hasil penelitian menunjukkan bahwa nilai NPV (Rp 36.644.364,08 lebih besar dari nol, Net B/C (2,56 lebih besar dari satu, IRR (11 % lebih besar dari suku bunga 6 %, serta payback period pada tahun ke-9 umur proyek 15 tahun. Berdasarkan kriteria indikator kelayakan finansial dapat disimpulkan bahwa usaha budidaya bambu layak secara finansial untuk diusahakan. Katakunci: Hasil Hutan Bukan Kayu (HHBK, budidaya bambu, studi kelayakan, analisis finansial   Financial analysis and feasibity study of bamboo cultivation  Abstract Bamboo cultivation is necessary to increase the population of bamboo clumps. The bamboo clumps tend to decrease due to the shift of used lands for residential or replaced by other crop comodities, which are considered more profitable. On the other hand, the need of bamboo for raw materials remain increase in line with population growth and the development of science. The important of the bamboo cultivation are to maintain the availability of its supply and to improve the quality of bamboo, which meet the market demands. This paper examined financial analysis of bamboo cultivation. Financial study was necessary to show whether

  18. ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI INDEPENDENSI PENAMPILAN AKUNTAN PUBLIK

    Directory of Open Access Journals (Sweden)

    Ardiani Ika S.

    2012-03-01

    Full Text Available Tujuan dari penelitian ini adalah untuk menguji secara empiris faktor-faktor yang mempengaruhi independensi penampilan akuntan publik baik secara parsial dan simultan. Faktor-faktor tersebut adalah financial interests, hubungan bisnis dengan klien, pelayanan asuransi dan audit, hubungan antara klien atau yg diaudit dengan auditor, kompetisi antara Kantor Akuntan Publik (KAP, ukuran KAP dan audit fee. Populasi dalam penelitian ini adalah para auditor di akuntan publik di Semarang tahun 2009. Metode penyeleksian sampel yang digunakan adalah convenience sampling dan jumlah respondennya 35. Alat analisis yang digunakan adalah multiple regression analysis. Dimulai dengan analisis kuantitatif untuk mengetes validitas dan reabilitas. Kemudian dilanjutkan uji asumsi klasik termasuk normality, multicollinearity, and heteroscedastisity. Hasil menunjukkan bahwa 6 variabel yang sudah dikaji secara simultan dan partial tersebut mempunyai efek yang signifikan terhadap independensi penampilan akuntan publik dengan R square 0.749. The objective of this study is to test empirically the factors that influence the independence of public accountant appearance both partially and simultaneously. The factors cover financial interests, business relationships with clients, assurance services and audit services, the length of relationship between client or auditee and auditor, the competition between Public Accountan Offices (KAPs, the size of KAP, and audit fee. The population in this study was the auditors who worked in the public accountant’s office in Semarang in 2009. The sample selection method is a convenience sampling and the  number of  respondents are 35. The Analysis tools used is multiple regression analysis. It starts by applying quantitative analysis to test the validity and reliability. Then, it is continued by testing the classical assumptions which include normality, multicollinearity, and heteroscedastisity. The result shows that the six

  19. Dove sta andando l'analisi musicale? Riflessioni sul VII EuroMac

    Directory of Open Access Journals (Sweden)

    Mario Baroni

    2014-01-01

    Full Text Available Come tutti i lettori della Rivista ormai sapranno, si è svolto a Roma dal 29 settembre al 2 ottobre di quest’anno, presso il Conservatorio di S. Cecilia, il settimo convegno europeo di analisi musicale (VII European Music Analysis Conference ossia VII EuroMac. Nel convegno, organizzato dal GATM e diretto da Giorgio Sanguinetti, sono state presentate 197 relazioni e svolti otto laboratori. Tutti i materiali sono stati riassunti in un volume (Programme and Abstract Book, Iter Edizioni di Subiaco curato da Egidio Pozzi e Antonio Cascelli.

  20. Biomimetic synthesis of selenium nanospheres by bacterial strain JS-11 and its role as a biosensor for nanotoxicity assessment: a novel se-bioassay.

    Science.gov (United States)

    Dwivedi, Sourabh; Alkhedhairy, Abdulaziz A; Ahamed, Maqusood; Musarrat, Javed

    2013-01-01

    Selenium nanoparticles (Se-NPs) were synthesized by green technology using the bacterial isolate Pseudomonas aeruginosa strain JS-11. The bacteria exhibited significant tolerance to selenite (SeO3(2-)) up to 100 mM concentration with an EC50 value of 140 mM. The spent medium (culture supernatant) contains the potential of reducing soluble and colorless SeO3(2-) to insoluble red elemental selenium (Se(0)) at 37°C. Characterization of red Se° product by use of UV-Vis spectroscopy, X-ray diffraction (XRD), atomic force microscopy (AFM) and transmission electron microscopy (TEM) with energy dispersive X-ray spectrum (EDX) analysis revealed the presence of stable, predominantly monodispersed and spherical selenium nanoparticles (Se-NPs) of an average size of 21 nm. Most likely, the metabolite phenazine-1-carboxylic acid (PCA) released by strain JS-11 in culture supernatant along with the known redox agents like NADH and NADH dependent reductases are responsible for biomimetic reduction of SeO3(2-) to Se° nanospheres. Based on the bioreduction of a colorless solution of SeO3(2-) to elemental red Se(0), a high throughput colorimetric bioassay (Se-Assay) was developed for parallel detection and quantification of nanoparticles (NPs) cytotoxicity in a 96 well format. Thus, it has been concluded that the reducing power of the culture supernatant of strain JS-11 could be effectively exploited for developing a simple and environmental friendly method of Se-NPs synthesis. The results elucidated that the red colored Se° nanospheres may serve as a biosensor for nanotoxicity assessment, contemplating the inhibition of SeO3(2-) bioreduction process in NPs treated bacterial cell culture supernatant, as a toxicity end point.

  1. ANALISIS PENGARUH IRADIASI FLUENS NEUTRON CEPAT TERHADAP BERILIUM REFLEKTOR REAKTOR RSG-GAS

    Directory of Open Access Journals (Sweden)

    Sri Kuntjoro

    2015-04-01

    Full Text Available Telah dilakukan analisis iradiasi fluens neutron cepat terhadap berilium reflektor reaktor RSG-GAS. Analisis dilakukan dengan cara melakukan pengukuran fluks neutron di posisi berilium elemen dan berilium blok yang berfungsi sebagai reflector. Selanjutnya dilakukan perhitungan untuk menentukan apakah ada pengaruh fluens neutron selama berilium berada di teras reaktor. Selain cara tersebut dilakukan pula visualisasi untuk memastikan ada tidaknya deformasi pada berilium akibat iradiasi. Hasil pengukuran fluks dan fluens neutron cepat maksimal pada daya 200 kW untuk berilium elemen posisi E-2 sebesar 2,30E+07 n/cm2s dan 4,19E+17 n/cm2, J-8 sebesar 3,70E+07 n/cm2s dan 6,74E+17 n/cm2. Hasil pengukutan pada posisi B-3 sebesar 2,19E+12 n/cm2s dan 3,99E+22 n/cm2, G-10 sebesar 2,12E+12 n/cm2s dan 3,86E+22 n/cm2, serta berilium blok posisi (5-6 sebesar 5,02E+07 n/cm2s dan 9,15E+17 n/cm2, (C-D sebesar 2,32E+07 n/cm2s dan 4,23E+17 n/cm2. Deformasi yang diperoleh untuk berilium elemen (∆L/L posisi E-2 sebesar 1,12E-08, J-8 sebesar 1,84E-08, B-3 sebesar 1,60E-03, posisi G-10 sebesar 1,55E-03, sedangkan pada berilium blok di posisi 5-6 sebesar 2,52E-08 dan C-D sebesar 1,13E-08. Dari hasil ini disimpulkan tidak terjadi deformasi pada berilium elemen dan berilium blok. Hasil ini dibuktikan pula dari pengamatan visual, dimana tidak terlihat adanya deformasi pada berilium tersebut. Kata kunci : fluks, fluens, berilium elemen, berilium blok   Analysis of influence fast neutron fluence irradiated to the RSG-GAS beryllium reflector have been done. Methods of analysis was carried out by measuring fluxs neutron in beryllium element and block positio that function as reflector. The calculation done for determination it is there any influence of neutron as long as beryllium in the core. Bisede that, visualization done to make sure it there is any deformation at beryllium as efect of irradiation. Fluxs and fluences of beryllium element measurement result in 200 k

  2. Analisis Pengaruh Konsentrasi Gas LPG Menggunakan Sensor TGS 2610 Berbasis Mikrokontroler AVR ATMega8535

    OpenAIRE

    Nurhalimah

    2011-01-01

    Telah dilakukan analisis kuantitatif gas dalam LPG. Penelitian ini dilakukan untuk mengukur konsentrasi gas LPG terhadap sensor. Metoda yang digunakan untuk mengukur konsentrasi gas LPG yaitu sensor gas semikonduktor jenis TGS 2610 keluaran Figaro yang digunakan untuk mendeteksi keberadaan gas. Sementara yang menjadi pusat pengendalian dari seluruh alat yang dirancang digunakan mikrokontroler AVR ATMega8535. Selain itu sistem yang dirancang dilengkapi LCD sebagai tampilan nilai konsentrasi ga...

  3. Analisis komoditas unggulan perikanan budidaya Kabupaten Pidie Jaya

    Directory of Open Access Journals (Sweden)

    Farok Afero

    2015-06-01

    Full Text Available Abstract. Snapper (Lates calcarifer, grouper (Epinephelus coioides, tiger shrimp (Penaeus monodon, vannamei shrimp (Litopenaeus vannamei and tilapia (Oreochromis niloticus are leading commodity worthly cultivated in Pidie Jaya. Bandar Baru and Tringgadeng an appropriate areas for black tiger shrimp while Jangka Buya and Ulim approriate areas for vannamei cultivation. AHP analysis showed black tiger shrimp is top priority based on the economic value while vannamei shrimp is top priority based on enterprise sustainability. Financial analysis of snapper, grouper, black tiger shrimp, vannamei shrimp and tilapia farming generated positive cash flow and NPV, IRR > 100%, the ratio of benefit to cost of production > 1,30 and payback period of investment costs  < 1 year, thus demonstrating the feasibility of cultivation of these leading commodities. Vannamei shrimp cultivation showed positive prospect as long the market offers premium price. Grouper and snapper had a positive outlook because high demand of high-quality fish in the international market. Keywords: Leading commodity; financial analysis; aquaculture; Pidie Jaya Abstrak. Komoditas kakap (Lates calcarifer, kerapu (Epinephelus coioides,udang windu (Penaeus monodon, udang vannamei (Litopenaeus vannamei dan nila (Oreochromis niloticus adalah komoditas unggulan yang layak dibudidaya di Kabupaten Pidie Jaya. Bandar Baru dan Tringgadeng merupakan kawasan yang layak untuk pengembangan komoditas udang windu sedangkan Jangka Buya dan Ulim layak untuk pengembangan komoditas udang vannamei. Analisis AHP menunjukkan komoditas udang windu menjadi prioritas utama untuk dikembangkan berdasarkan nilai ekonomi sedangkan udang vannamei menjadi prioritas utama berdasarkan keberlanjutan usaha. Analisis indikator keuangan budidaya kakap, kerapu, udang windu, vannamei dan nila menunjukkan usaha budidaya komoditas unggulan menghasilkan arus kas kumulatif dan NPV positif, nilai  IRR diatas 100%, rasio keuntungan

  4. Analisis Film Horor Indonesia Produksi Tahun 2014 (Studi Kasus: Mall Klender dan Kamar 207

    Directory of Open Access Journals (Sweden)

    Dedi Sukatno Sembiring Meliala

    2016-02-01

    Full Text Available Abstrak Film horor erat kaitannya dengan tokoh antagonis yang menimbulkan ketakutan pada penonton dalam bentuk makhluk supranatural seperti hantu, roh jahat dan sebagainya. Karakteristik film dengan genre horor membuat penonton terbawa suasana dengan alur ceritanya yang menakutkan. Namun, beberapa dari film horor Indonesia menyajikan adegan-adegan yang kurang sopan bahkan tergolong asusila atau porno. Untuk itu, penelitian ini ingin melihat apakah terdapat konten pornografi pada film Mall Klender dan Kamar 207 yang merupakan film horor Indonesia terlaris di tahun 2014. Analisis dilakukan dengan melihat pandangan dan penilaian 30 responden dengan karakteristik yaitu penonton film horor Indonesia yang berusia 20-40 tahun. Berdasarkan hasil analisis, tidak didapatkan konten pornografi pada film Mall Klender dan Kamar 207. Adegan-adegan yang terindikasi sebagai konten pornografi ternyata masih dapat diterima oleh penonton sebagai adegan yang berada dalam batas kewajaran dan mendukung pembawaan suasana dan kesan dalam cerita yang disampaikan. Kata Kunci: film horror Indonesia, analisis konten, pornografi Abstract The horror film is closely related to the antagonist that causes fear for audience in the form of supernatural creatures such as ghosts, demons and so on. Characteristic of the horor film is to make the audience carried away with the scary plot. However, some of the existing Indonesian horror film presents scenes that classified as obscene or pornographic. Therefore, this study wanted to see if there are any pornographic content on the film Klender Mall and Room 207 is the best-selling Indonesian horror movie in 2014. The analysis was done by looking at the view and assessment of 30 respondents which are Indonesian horror movie goers aged 20-40 years. Based on the analysis, there is no founding of pornographic content on the film Klender Mall and Room 207. The scenes that indicated as pornographic content was still acceptable by the audience

  5. Analysis system and remote monitoring of atmospheric discharges; Sistema de analisis y monitoreo remoto de descargas atmosfericas

    Energy Technology Data Exchange (ETDEWEB)

    Zabre Borgaro, Eric; Rodriguez Padilla, Ma. Consuelo [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1996-12-31

    A system for analysis and monitoring of atmospheric discharges (SAMDA (Sistema de Analisis y Monitoreo de Descargas Atmosfericas) (lightnings)) in an electronic device that subsequently transmits these data as automatic processing or by request of a user from a computer operating as a remote station, is described. Also, the characteristics of the SAMDA, its evolution, and the challenges encountered along the development of this project and comments on possible improvements to the equipment and data recordings of this nature, are described. [Espanol] Se presenta el sistema de analisis y monitoreo de descargas atmosfericas (SAMDA) utilizado en la deteccion y registro de descargas atmosfericas (rayos) en un equipo electronico que posteriormente transmite estos datos como procesamiento automatico o por peticion de un usuario desde una computadora, operando como estacion remota. Asimismo, se describen las caracteristicas del SAMDA, su evolucion, los retos encontrados a lo largo del desarrollo de este proyecto y comentarios sobre posibles mejoras a equipos y registros de datos de esta naturaleza.

  6. Analysis system and remote monitoring of atmospheric discharges; Sistema de analisis y monitoreo remoto de descargas atmosfericas

    Energy Technology Data Exchange (ETDEWEB)

    Zabre Borgaro, Eric; Rodriguez Padilla, Ma Consuelo [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1997-12-31

    A system for analysis and monitoring of atmospheric discharges (SAMDA (Sistema de Analisis y Monitoreo de Descargas Atmosfericas) (lightnings)) in an electronic device that subsequently transmits these data as automatic processing or by request of a user from a computer operating as a remote station, is described. Also, the characteristics of the SAMDA, its evolution, and the challenges encountered along the development of this project and comments on possible improvements to the equipment and data recordings of this nature, are described. [Espanol] Se presenta el sistema de analisis y monitoreo de descargas atmosfericas (SAMDA) utilizado en la deteccion y registro de descargas atmosfericas (rayos) en un equipo electronico que posteriormente transmite estos datos como procesamiento automatico o por peticion de un usuario desde una computadora, operando como estacion remota. Asimismo, se describen las caracteristicas del SAMDA, su evolucion, los retos encontrados a lo largo del desarrollo de este proyecto y comentarios sobre posibles mejoras a equipos y registros de datos de esta naturaleza.

  7. Using Paleoecology to Inform Land Management as Climates Change: An Example from an Oak Savanna Ecosystem

    Science.gov (United States)

    Spencer, Jessica D.; Brunelle, Andrea; Hepola, Tim

    2017-12-01

    Oak savanna, a transitional ecosystem between open prairie and dense oak forest, was once widespread in Minnesota. Upon European settlement much of the oak savanna was destroyed. Recently, efforts to restore this ecosystem have increased and often include the reintroduction of fire. Though fire is known to serve an important role within oak savannas, there are currently few studies which address fire regimes on timescales longer than the last century. This research presents a paleoecological history of Sherburne National Wildlife Refuge (SNWR) in MN, USA, spanning the last 8000 years. The objectives of this study were to use charcoal, pollen, and magnetic susceptibility of lake sediments collected from Johnson Slough (JS) within the refuge to evaluate the natural range of variability and disturbance history of the oak savanna within the refuge, assess the success of current restoration strategies, and add to the regional paleoecological history. The mid/late Holocene period of the JS record shows a period of high fire activity from ca. 6500 to 2600 cal year BP, with a shift from prairie to oak savanna occurring over this same period. A (possibly agricultural) disturbance to JS sediments affected the period from ca. 2600 cal year BP to 1963 AD, which includes the time of Euro-American settlement. However, the destruction and subsequent restoration of the oak savanna is evident in a pollen ratio of Quercus:Poaceae, indicating that current restoration efforts have been successful at restoring the oak savanna to within the natural range of variability seen just prior to destruction.

  8. ANALISIS KENDALA POTENSIAL PENERAPAN TOTAL QUALITY MANAGEMENT HOTEL PLAZA SEMARANG

    Directory of Open Access Journals (Sweden)

    Hendrajaya -

    2010-03-01

    Full Text Available Penelitian ini bertujuan untuk menemukan faktor-faktor yang terbentuk dari kendala penerapan Total Quality Management (TQM, sebagai upaya untuk menganalisis masalah-masalah potensial dari penerapan TQM di Hotel Plaza, Semarang. Sampel dari penelitian ini sejumlah 65 karyawan Hotel Plaza, Semarang yang terdiri dari manajer dan staf. Teknik analisis menggunakan Faktor Analisis. Hasil penelitian menunjukkan, bahwa kendala potensial dari implementasi TQM dapat disimpulkan menjadi lima faktor, yaitu faktor inkonsistensi, visi-misi, transformasi budaya, manajerial dan manajemen kualitas. Penelitian ini memberikan rekomendasi bahwa peningkatan fungsi-fungsi korporat melalui optimalisasi kualitas sebagai strategi bisnis dan orientasi pada kepuasan konsumen dengan melibatkan seluruh anggota organisasi, akan menjadi dasar untuk memaksimalkan daya saing perusahaan dalam hal produk, layanan, SDM, lingkungan dan seluruh proses yang dapat mendukung upaya perbaikan produktivitas. This study aims to determine the constraint factors and to analyze the potential problems of TQM implementation of Plaza Semarang Hotel. The sample of 65 employees of TQM implementation of Plaza Semarang Hotel, consist of managers and staffs. Factor analysis is used to achieve the results of the potential constraint implementation of Total Quality Management which can be summarized into five factors, they are: the factor of inconsistencies, the factor of vision and mission, cultural transformation factors, managerial factors and the factors of quality management. In order to increase the corporate functions through the optimization of quality as a business strategy and to achieve customer satisfaction, this study suggests that all members of the organization should be involved by the company as on-going basis to maximize the competitiveness of the organization on products, services, human resources, environment and all processes that support productivity improvement.

  9. Analisis Zona Permeabel Fluida Sistem Panas Bumi Gunungapi Slamet Berdasarkan Analisis Kerapatan Kelurusan Citra SRTM Dan Struktur Geologi

    Directory of Open Access Journals (Sweden)

    Sachrul Iswahyudi

    2016-03-01

    Full Text Available Keberadaan manifestasi panasbumi di sekitar Gunungapi Slamet tidak dapat dipisahkan dari zona-zona permeabilitas yang berkembang. Lokasi-lokasi lulus air tersebut (zona permeabel yang memungkinkan terbentuknya sirkulasi fluida tempat air masuk untuk mengisi reservoir panas bumi dan air keluar ke permukaan bumi sebagai manifesatasi mata air panasbumi di sekitar Gunungapi Slamet. Publikasi yang berupa hasil penelitian ini mencoba mengidentifikasi zona-zona permeabel tersebut berdasarkan anaslisis kerapatan kelurusan yang terekam dalam citra SRTM. Identifikasi kelurusan-kelurusan pada citra berdasarkan komponen-komponen interpretasi citra, yaitu tona, tekstur, pola, bentuk dan relief. Hasil analisis tersebut dikompilasi dengan data struktur geologi regional yang sebelumnya telah diidentifikasi dan data lapangan berupa manifestasi mata air panas. Lokasi-lokasi dengan kerapatan kelurusan yang tinggi pada citra SRTM umumnya bersesuaian dengan zona struktur geologi regional keberadaan manifestasi mata air panas. Daerah tersebut memanjang relatif utara-selatan di bagian barat dan timur-barat di bagian selatan peta. Daerah-daerah inilah yang merupakan daerah lulus air tempat fluida bersirkulasi membentuk sistem panasbumi Gunungapi Slamet.

  10. Analisis Pengaruh Parameter Operasional dan Penggunaan Stabilizer terhadap Perilaku Arah Belok Mobil Toyota Fortuner 4.0 V6 SR (AT 4X4

    Directory of Open Access Journals (Sweden)

    Deva Andriansyah

    2017-01-01

    Full Text Available Salah satu tipe mobil yang diminati oleh masyarakat Indonesia yaitu Toyota Fortuner yang termasuk dalam kelas mobil SUV (sport utility vehicle. Dalam pengoperasiannya mobil SUV harus mampu memberikan keamanan dan kenyamanan bagi pengendaranya. Salah satu faktor penunjang dari segi keamanan mobil ini yaitu perilaku arah beloknya. Dengan harga jual yang relatif tinggi di Indonesia, diharapkan mobil ini dapat memberikan perilaku arah belok yang baik. Terdapat dua tahapan dalam peneltian ini yaitu tahap analisis dan uji jalan pada radius belok tetap, 10 meter. Pada tahap analisis dilakukan perhitungan berdasarkan analisa slip, skid, dan guling untuk mengetahui perilaku arah belok mobil dengan variasi pada parameter operasionalnya yaitu: jumlah penumpang, kecepatan, sudut belok, kondisi permukaan jalan, dan tekanan ban. Selain itu, analisis pengaruh penggunaaan stabilizer terhadap perilaku arah belok mobil juga dilakukan. Uji jalan dilakukan untuk mengetahui Koefisien Understeer (KUS dari mobil tersebut pada jalan aspal dan tanah dengan kondisi mobil tanpa dan menggunakan stabilizer. Hasil yang didapatkan dari uji jalan akan dibandingkan dengan hasil dari analisis perhitungan. Hasil penelitian ini menunjukkan bahwa mobil Toyota Fortuner mengalami kondisi belok paling baik ketika dinaiki oleh 2 orang penumpang dengan tekanan ban sebesar 35 Psi dan melintas pada jalan aspal karena kendaraan lebih sedikit mengalami oversteer dan memiliki (KUS positif terkecil serta tidak mudah mengalami skid. Penggunaan stabilizer pada mobil Toyota Fortuner tidak berpengaruh terhadap perilaku arah beloknya karena KUS yang dihasilkan pada uji jalan nilainya hampir sama yaitu 1,8045 dan 1,8115 pada jalan aspal serta 2,151 dan 2,1641 pada jalan tanah. Namun, penggunaan stabilizer bermanfaat untuk memperkecil sudut guling ketika mobil berbelok.

  11. Study of an automatized experimental device for the irradiation of a radioactive target

    International Nuclear Information System (INIS)

    Claverie, G.

    1996-01-01

    In order to solve the enigma of solar neutrinos, a team of physicians of the nuclear research center of Bordeaux-Gradignan and of the center of nuclear spectroscopy and mass spectroscopy of Orsay (France) decided to measure again the cross section of the beryllium-proton nuclear reaction at the lowest possible energies. This measurement requires the design of an automatized experimental device to irradiate in a specific way a beryllium target with an accelerated proton beam. The aim of this work is the study of such a device for an energy range of 800 to 300 KeV. This device comprises a particle multi-detector and a shutter for the irradiation of the target and the counting of the reaction products according to a programmable time sequence. The advantage of this setup is to allow an important bombardment of the target and to ensure its cooling. This device is automatically controlled thanks to a micro-controller, actuators (step motors and electrostatic deflector). It includes some beam diagnosis elements controlled by step motors and a target temperature monitoring system controlling a safety valve. The management of the experiment cell vacuum has led to the design of a vacuum monitor allowing the precise follow up of the vacuum and the control of the safety valves of the device. The nuclear instrumentation necessary to be implemented for this measurement is also presented. (J.S.)

  12. Analisis Faktor Pembentuk Ekuitas Merek Toyota dan Daihatsu di Indonesia (Studi Komparasi pada Masyarakat Bandung)

    OpenAIRE

    Sigiro, Cristine Afriani; Rachma Putri, Yuliani; Ilfandy Imran, Ayub

    2016-01-01

    Toyota dan Daihatsu merupakan dua merek otomotif (mobil) yang sangat fenomenal di kalangan masyarakat Indonesia. Produk dari kedua merek tersebut memiliki persamaan yang identik, namun Toyota memasarkan produknya lebih mahal dibandingkan Daihatsu. Tujuan penelitian ini untuk mengetahui perbandingan ekuitas merek Toyota dan Daihatsu menurut masyarakat Bandung. Penelitian ini menggunakan paradigma penelitian positivistik dengan metode penelitian studi komparatif melalui teknik analisis data yan...

  13. Identifiksi Sebaran Litologi berdasarkan Analisis Data Resistivitas di Gunung Wungkal

    Directory of Open Access Journals (Sweden)

    Nurul Dzakiya

    2017-05-01

    Full Text Available Analisis data untuk mengidentifikasi sebaran litologi yang memiliki potensi bahan galian industri di Daerah Gunung Wungkal Yogyakarta dengan menggunakan metode resistivitas dan survei geologi permukaan telah dilakukan. Hasil korelasi kedua data tersebut menunjukkan sebaran litologi merupakan pelapukan intrusi batuan beku yang kemudian menghasilkan material lempung (6,0-10 m, lempung pasiran (11-30 m dan lapukan batuan diorit (30-55 m yang berada di kedalaman berbeda. Ketebalan batuan di permukaan sekitar 225-231 meter berdasarkan penampang peta geologi dengan arah sebaran dari Barat Laut hingga Tenggara. Proses pelapukan dan alterasi di daerah ini intensif (alterasi argilik dengan jenis morfologi perbukitan intrusi terdenudasi dan dataran Alluvial.

  14. ANALISIS FUNDAMENTAL MAKRO DAN INTEGRASI PASAR SAHAM DUNIA DENGAN BURSA EFEK INDONESIA

    Directory of Open Access Journals (Sweden)

    Luh Gede Sri Artini

    2017-11-01

    Full Text Available Penelitian ini merupakan gabungan dari penelitian sebelumnya mengenai hubungan antara harga saham dengan kinerja ekonomi makro, dan penelitian mengenai integrasi Pasar Modal internasional.Variabel ekonomi makro dalam penelitian ini dibatasi pada pertumbuhan PDB, tingkat suku bunga SBI dan nilai Kurs dolar Amerika terhadap Rupiah dan Indeks saham digunakan adalah Indeks Dow Jones, Indeks Saham Australia, Indeks Shanghai dan Indeks Singapura. Data dikumpulkan dari tahun 2011 sampai tahun 2015 secara bulanan dengan teknik analisis regresi linier dengan bantuan Statistical Package For Social Science (SPSS

  15. TUGAS DAN WEWENANG PUSAT PELAPORAN DAN ANALISIS TRANSAKSI KEUANGAN (PPATK DALAM PEMBERANTASAN TINDAK PIDANA PENCUCIAN UANG

    Directory of Open Access Journals (Sweden)

    Johari Johari

    2014-03-01

    Full Text Available Tugas dan wewenang Pusat Pelaporan dan Analisis Transaksi Keuangan (PPATK terdapat di dalam Pasal 26 dan Pasal 27 Undang-Undang No. 25 Tahun 2003 tentang Tindak Pencucian Uang. Berdasarkan ketentuan tersebut, tugas dan wewenang PPATK tersebut bertujuan untuk mendeteksi terjadinya tindak pidana pencucian uang, dan membantu penegakan hukum yang berkaitan dengan pencucian uang, termasuk tindak pidana asal yang melahirkannya (predicate offences. Namun, Peranan PPATK akan berjalan secara efektif apabila aparat penegak hukum seperti Kepolisian, Kejaksaan, Pengadilan, Bea dan Cukai, para regulator seperti Bank Indonesia, Departemen Keuangan, Badan Pengawas Pasar Modal serta Penyedia Jasa Keuangan, industri perbankan, asuransi, perusahaan pembiayaan, dana pensiun, perusahaan efek, pengelola reksadana, media massa, masyarakat bekerjasama secara terorganisir dan terpadu dalam pemberantasan tindak pencucian uang di Indonesia. Dengan kewenangan yang dimilikinya, PPATK dapat mengejar hasil dari kejahatan, apabila hasil kejahatan tersebut dapat dikejar dan disita maka negara dengan sendirinya akan mengurangi tindak kejahatan itu sendiri. Kata kunci : Pencucian uang, tindak pidana pencucian uang (money laundering, kejahatan terorganisir, dan Pusat Pelaporan dan Analisis Transaksi Keuangan (PPATK.

  16. ANALISIS KELAYAKAN DAN SENSITIVITAS HARGA INPUT PADA USAHA BUDIDAYA IKAN LELE DALAM KOLAM TERPAL DI KOTA BANJARBARU PROVINSI KALIMANTAN SELATAN

    Directory of Open Access Journals (Sweden)

    Idiannor Mahyudin

    2016-10-01

    Full Text Available Salah satu kegiatan ekonomi berbasis sumberdaya hayati pada sektor perikanan adalah kegiatan budidaya ikan.  Tetapi dengan keterbatasan lahan yang dimiliki dan untuk memanfaatkan lahan pekarangan supaya bernilai produktif maka masyarakat Banjarbaru banyak mengusahakan budidaya ikan lele di kolam terpal. Penelitian ini bertujuan untuk (1 menganalisis layak atau tidaknya usaha budidaya ikan lele di kolam terpal; (2 menganalisis pengaruh perubahan harga input terhadap usaha budidaya ikan lele di kolam terpal; (3 mengetahui permasalahan yang dihadapi oleh pelaku usaha budidaya  ikan lele di kolam terpal di Kotamadya Banjarbaru. Penelitian ini menggunakan metode survei dan wawancara. Data yang dikumpulkan meliputi data primer dan data sekunder. Lokasi sampel ditentukan secara sengaja (purposive, yakni Kotamadya Banjarbaru. Wawancara dilakukan terhadap petani ikan  yang aktif mengelola kegiatan usaha budidaya  ikan lele di kolam terpal, yakni sebanyak 200 petani ikan.  Penetapan jumlah sampel dilakukan secara random mengingat populasi yang homogen. Analisis data untuk menjawab tujuan pertama, yakni menganalisis kelayakan investasi usaha budidaya ikan lele di kolam terpal , digunakan perhitungan pada kriteria investasi yang meliputi Net Present Value (NPV, Net Benefit Cost Ratio (Net BCR, Internal Rate of Return (IRR dan Payback Period.   Untuk menjawab tujuan kedua dilakukan pengujian terhadap hasil kelayakan usaha pada metode di atas dengan mempertimbangkan adanya kenaikan harga pakan. Selanjutnya untuk menjawab tujuan ketiga, yakni mengetahui permasalahan yang dihadapi pelaku usaha budidaya ikan lele di kolam terpal, digunakan analisis deskriptif dengan cara mengkaji data-data primer/sekunder dan selanjutnya memaparkannya secara tertulis. Hasil analisis kelayakan usaha diperoleh nilai NPV 12% sebesar Rp 96.600,081 > 0, nilai B/C 12% = 2,089 > 1 dan nilai IRR = ~ (tidak terhingga  > dari tingkat bunga berlaku. Dari hasil kelayakan usaha

  17. Analisis Gameplay Game Genre Virtual Pet

    Directory of Open Access Journals (Sweden)

    Abi Senoprabowo

    2015-02-01

    Full Text Available Game adalah struktur interaktif yang membuat pemain berjuang menuju sebuah tujuan. Game dapat memberikan emosi dan mood, menghubungkan dengan orang latihan, sarana latihan, serta dapat memberikan edukasi. Salah satu game yang berkembang saat ini adalah game bergenre Virtual pet. Game virtual pet merupakan game simulasi memelihara sesuatu. Virtual pet memiliki gameplay yang menarik dan menyenangkan yang membuat pemain seolah-olah benar-benar memiliki binatang peliharaan mereka sendiri. Virtual pet dianggap oleh sebagian besar penggunanya dapat memberikan kegembiraan serta rasa kasih sayang karena tingkat interaksinya yang baik. Banyak pengembang game pemula yang mengembangkan genre ini sebagai game yang mereka buat karena kemudahaan dan tingkat penggunanya yang banyak. Akan tetapi banyak dari pengembang game pemula tidak memperhatikan tingkat keberlanjutan game virtual pet yang mereka buat sehingga membuat pemain cepat bosan. Pada penelitian ini, analisis game bergenre virtual pet yang sudah sukses dibuat seperti Zombigotchi, Tamagotchi Unicorn, dan Bird Land, diharapkan dapat membantu para pengembang game pemula agar mengetahui cara merancang dan mengembangkan game virtual pet dengan baik. Kata Kunci: game, gameplay, virtual pet

  18. ANALISIS RESIDU PESTISIDA PIRETRIN DALAM TOMAT DAN SELADA DARI BEBERAPA PASAR DI JAKARTA

    Directory of Open Access Journals (Sweden)

    D. Mutiatikum

    2012-10-01

    Full Text Available Penggunaan pestisida untuk budidaya komoditi pertanian memungkinkan adanya residu pestisida dalam sayuran sehingga konsumen berisiko tercemar pestisida yang merupakan zat toksik  sehingga diperlukan pemantmwn kadar residu dalam sayuran terutama yang langsung dikonsumsi tanpa dimasak. Penetapan  residu pestisida dilakukan dengan menggunakan kromatografi gas (GC. Hasil analisis residu pestisida golongan peretrin dalam tomat dan selada yang disampling dari pasar induk, pasar tradisional. pasar swalayan dan hipermarket yang berada diwilayah Jakarta menunjukkan hasil yang negatif (tidak terdeteksi.

  19. Iron-Dependent Enzyme Catalyzes the Initial Step in Biodegradation of N-Nitroglycine by Variovorax sp. Strain JS1663.

    Science.gov (United States)

    Mahan, Kristina M; Zheng, Hangping; Fida, Tekle T; Parry, Ronald J; Graham, David E; Spain, Jim C

    2017-08-01

    Nitramines are key constituents of most of the explosives currently in use and consequently contaminate soil and groundwater at many military facilities around the world. Toxicity from nitramine contamination poses a health risk to plants and animals. Thus, understanding how nitramines are biodegraded is critical to environmental remediation. The biodegradation of synthetic nitramine compounds such as hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) has been studied for decades, but little is known about the catabolism of naturally produced nitramine compounds. In this study, we report the isolation of a soil bacterium, Variovorax sp. strain JS1663, that degrades N -nitroglycine (NNG), a naturally produced nitramine, and the key enzyme involved in its catabolism. Variovorax sp. JS1663 is a Gram-negative, non-spore-forming motile bacterium isolated from activated sludge based on its ability to use NNG as a sole growth substrate under aerobic conditions. A single gene ( nnlA ) encodes an iron-dependent enzyme that releases nitrite from NNG through a proposed β-elimination reaction. Bioinformatics analysis of the amino acid sequence of NNG lyase identified a PAS (Per-Arnt-Sim) domain. PAS domains can be associated with heme cofactors and function as signal sensors in signaling proteins. This is the first instance of a PAS domain present in a denitration enzyme. The NNG biodegradation pathway should provide the basis for the identification of other enzymes that cleave the N-N bond and facilitate the development of enzymes to cleave similar bonds in RDX, nitroguanidine, and other nitramine explosives. IMPORTANCE The production of antibiotics and other allelopathic chemicals is a major aspect of chemical ecology. The biodegradation of such chemicals can play an important ecological role in mitigating or eliminating the effects of such compounds. N -Nitroglycine (NNG) is produced by the Gram-positive filamentous soil bacterium Streptomyces noursei This study reports the

  20. Analisi dei cicli del mercato immobiliare: un applicazione sui dati italiani

    Directory of Open Access Journals (Sweden)

    Maurizio Festa!

    2012-06-01

    Full Text Available Utilizzando i dati italiani, sulla base dell'approccio teorico del ciclo "a nido d'ape" proposto da Janssen, Kruijt e Needham nel 1994, questo articolo propone un ulteriore contributo allo studio delle dinamiche del mercato immobiliare italiano. Utilizzando alcuni indicatori del mercato, si presentano i grafici del ciclo a nido d'ape per tutte le regioni e per le principali città. Tecniche di cluster analysis sono utilizzate per raggruppare le regioni che mostrano andamenti simili. L'obiettivo finale dell'analisi è quindi quello di esaminare il territorio nazionale in termini di sviluppo ed evoluzione del mercato delle abitazioni.

  1. PENINGKATAN KEMAMPUAN ANALISIS MASALAH EKONOMI DENGAN MODEL PEMBELAJARAN PROBLEM BASED LEARNING (STUDI PADA SISWA KELAS X IIS 3 SMA 1 BAE KUDUS TAHUN AJARAN 2014/2015

    Directory of Open Access Journals (Sweden)

    Kurnia Norma Handayani

    2015-02-01

    Full Text Available atar belakang penelitian ini adalah karena kurangnya kemampuan analisis masalah ekonomi sehingga menyebabkan kurangnya pemahaman siswa akan materi dan berpengaruh terhadap hasil belajar siswa kurang optimal, selain itu karena metode pembelajaran yang digunakan tidak tepat yaitu menggunakan ceramah tanpa variasi sedangkan karakter materinya adalah teoritis dan membutuhkan analisis. Penelitian ini bertujuan untuk mengetahui peningkatan kemampuan analisis masalah ekonomi dengan model pembelajaran Problem Based Learning dan mengetahui penerapan model pembelajaran Problem Based Learning untuk meningkatkan kemampuan analisis masalah ekonomi. Subyek penelitian ini adalah siswa kelas X IIS 3 SMA 1 Bae Kudus. Penelitian ini merupakan penelitian tindakan kelas yang dilakukan dalam 2 siklus. Hasil penelitian ini diperoleh data kemampuan analisis siswa siklus I nilai rata-rata 73,94 dengan ketuntasan klasikal sebesar 52,94%, pada siklus II nilai rata-rata meningkat menjadi 82,29 dengan ketuntasan klasikal sebesar 82,35%, aktivitas siswa pada pembelajaran siklus I cukup dan pada siklus II meningkat menjadi sangat baik. The background of this research is the lack of knowledge in economic problems so students learning outcomes less optimal, moreover because the learning method that is used is not appropriate to use the oral speech without variation while the character is doctrinaire and needing analysis. This research aims to know improving the analysis ability on the subject economic problems with problem based learning model and how the use problem based learning can improving the analysis ability on the subject economic problems. The subject of this research is the class X IIS 3 SMA 1 Bae Kudus. This study is an action research conducted in two cycles. The research finding showed that analysis ability in learning cycle I average grade is 73,94 with percentage of classical completeness is 52,94%, in cycle II average grade increase to 82,29 with percentage of

  2. ANALISIS FAKTOR KEHADIRAN DOSEN DI UNIVERSITAS X

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    Annisa Mulia Rani

    2016-10-01

    Full Text Available Aspek kualitas pekerjaan berkaitan langsung dengan waktu yang khusus digunakan dosen untuk mengembangkan kemampuan. Maka untuk merealisasikan kualitas dosen yang terbaik , pihak manajemen khusunya dekan membuat peraturan untuk kehadiran dosen adalah minimal 25 jam/minggu. Dengan peraturan ini diharapkan dosen dapat melaksanakan beban kerja dosen sebaik-baiknya. Peraturan ini tertulis dan tertuang pada SK Dekan No 20/2006 pada kampus X. Dengan Menggunakan Analisis faktor mencoba menemukan hubungan atar sejumlah variable-variabel yang awalnya saling independen satu dengan yang lain dimana variable penyebab kekurangan jam dosen datang/minggu adalah keluaraga, manajemen, hubungan social, fasilitas pengajaran, jarak/lokasi, kompensasi transport. Berdasarkan uji Bartley test dan Measure sample of adequate yang pertama maka dengan nilai sig 0.04 dan msa 0.540 . Dengan menggunakan metode principal component analysis maka pembentukan factor hanya ada 1 componen karena nilai eigen value yang mempunyai nilai diatas 1. Faktor pembentuk baru yaitu manajemen, kompensasi dan jarak menjadi satu component.

  3. ANALISIS PSAK NO. 27 TENTANG AKUNTANSI PERKOPERASIAN DAN PENGARUHNYA TERHADAP KESEHATAN USAHA PADA KPRI

    Directory of Open Access Journals (Sweden)

    Muhammad Khafid

    2012-03-01

    Full Text Available Tujuan dari penelitian ini adalah untuk menganalisis kepatuhan penerapan PSAK 27 (Cooperative Accounting, dan untuk menganalisa dampak  kepatuhan penerapan PSAK 27 (Cooperative Accounting  pada pengoperasian kinerja KPRI di kota Semarang. Populasinya adalah 62 KPRI di kota Semarang, dan sempel yang digunakan adalah 29 KPRI. Metode pengumpulan datanya adalah dokumentasi dan kuesioner. Metode analisis data adalah analisis deskriptif  dan statistik inferensial. Hasil penelitian memperlihatkan bahwa KPRI di kotamadya Semarang dikategorikan cukup dan terbukti bahwa hipotesis menyatakan bahwa tingkat kepatuhan penerapan PSAK 27 berpengaruh terhadap pertumbuhan usaha. Abstract The purposes of this research are to analyze the implementation compliance of PSAK 27 (Cooperative Accounting, and to analyze the effects of implementation compliance of PSAK 27 (Cooperative Accounting on KPRI performance  in Semarang Municipality. The population are 62 KPRIs in Semarang.However, there are only twenty nine KPRIs become the samples. The methods for collecting the data are documentation and questionairre. Then, for analyzing the data, it requires descriptive analysis and inferential analysis. The results of study shows that KPRIs in Semarang Municipality are categorized as fair and hypothesis states that the level of implementation compliance of PSAK 27 is influencial to the business has successfully proven.Keywords:  cooperative accounting; compliance

  4. ANALISIS POSISI BERSAING UNTUK MENENTUKAN STRATEGI PEMASARAN INDUSTRI KRIPIK TEMPE DI KOTA MALANG

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    Rusno Rusno

    2014-11-01

    Full Text Available Industri kripik tempe di desa Sanan Malang merupakan bagian dari UMKM mengalami perkembang-an yang cukup baik. Hingga akhir tahun 2013 kemarin berjumlah kurang lebih 65 pengrajin, bahkan saat ini Sanan sudah menjadi sentra industri kecil penghasil kripik tempe dan menjadi salah satu pro-duk unggulan kota Malang. Namun dalam perjalanannya industri ini banyak mengalami masalah diantaranya banyak pesaing yang terus masuk dalam bisnis ini. Hal ini mengakibatkan persaingan yang semakin ketat sehingga para pelaku harus dapat menentukan strategi untuk dapat memenangkan persaingan, maka Tujuan dalam penelitian ini adalah untuk mengetahui bagaimana posisi bersaing dan penetapan strategi pemasaran produsen kripik tempe di kota Malang. Jenis penelitian ini adalah confirmatory research. Sebagai populasinya adalah pengusaha kripik tempe yang berlokasi di kecamatan Blimbing kota Malang yang berjumlah 65 pemilik home industri. Sampel dilakukan dengan teknik Simple random sampling berjumlah 33 pengusaha industri kripik tempe. Pengambilan data dilakukan dengan kuesioner, dan teknik analisis data dengan teknik deskriptif dan tabulasi silang. Berdasarkan analisis data didapatkan hasil penelitian bahwa posisi bersaing industri kripik tempe di Sanan terdapat 4 cluster yang terbagi dalam : Cluster 1 (pemimpin pasar/market leader beranggota-kan 1 perusahaan. Cluster 2(penceruk pasar/market nicher beranggotakan 13 perusahaan, Cluster 3 (penantang pasar/market challenger beranggotakan 8 perusahaan dan cluster 4 (pengikut pasar /market follower beranggotakan 11 perusahaan. 

  5. ANALISIS PERANCANGAN BUSINESS INTELLIGENCE BERBASIS SAAS CLOUD COMPUTING

    Directory of Open Access Journals (Sweden)

    I Gede Adnyana

    2014-05-01

    Full Text Available Persaingan bisnis yang ketat, mendorong setiap perusahaan menyusun strategi bisnis agar dapat bertahan dari para pesaing. Penyusunan strategi bisnis mutlak memerlukan informasi yang tepat dan akurat, pengolahan hingga analisis data yang menghasilkan informasi yang tepat dan akurat menjadi proses yang sangat penting. Business Intelligence (BI menawarkan solusi bisnis untuk menganalisis data dan memungkinkan suatu perusahaan untuk mengambil keputusan untuk meningkatkan keuntungan dan kinerja bisnis. Namun, BI mahal untuk diimplementasikan, memerlukan biaya pemeliharaan yang tidak sedikit dan infrastruktur yang kuat. Hal ini mendorong perusahaan mengurangi biaya tetapi masih memiliki teknologi yang tepat untuk memungkinkan mereka untuk membuat keputusan, mengidentifikasi peluang dan proaktif mengidentifikasi risiko yang dapat mempengaruhi bisnis. Konsep Software as a Service (SaaS Cloud Computing dapat menjawab tantangan yang dihadapi BI. Sebelum merancang BI berbasis SaaS perlu diketahui parameter-parameter evaluasi hingga kelebihan dan kekurangannya.

  6. ANALISIS PERILAKU PENYUSUN ANGGARAN DALAM PERSPEKTIF KEAGENAN PADA KABUPATEN DAN KOTA DI PROVINSI SULAWESI SELATAN

    OpenAIRE

    ILMI, A. NURUL

    2016-01-01

    2016 Analisis Perilaku Penyusun Anggaran dalam Perspektif Keagenan pada Kabupaten dan Kota di Provinsi Sulawesi Selatan Analysis of Budget Compiler???s Behavior within the Agency Perspective in Regency and City of South Sulawesi Province A. Nurul Ilmi Mediaty Aini Indrijawati Penelitian ini bertujuan untuk menganalisis pengaruh perubahan Pendapatan Asli Daerah dan perubahan Dana Perimbangan terhadap perilaku oportunistik penyusun anggaran yang menjelaskan mengenai hubungan k...

  7. Analisis Peranan Franchisor Terhadap Suksesnya Bisnis Franchise Pada Mc. Donald’s Cabang Ring Road Medan

    OpenAIRE

    Simarmata, Leonardo

    2012-01-01

    Tujuan penelitian ini adalah untuk mengetahui dan menganalisis peranan franchisor dalam promotion, support service, training, control system dan communication terhadap suksesnya bisnis franchise pada Mc Donald’s Cabang Ring Road Medan. Pengumpulan data primer diperoleh dengan cara memberikan daftar pertanyaan (questionaire) dan melakukan wawancara (interview) secara mendalam (depth interview) kepada pemilik usaha M. Donald’s Cabang Ring Road Medan. Teknik analisis data penelitian ini ad...

  8. ENCAPAI SUMBER DAYA MANUSIA UNGGUL (ANALISIS KINERJA DAN KUALITAS PELAYANAN

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    Ketut Sudarma

    2012-03-01

    Full Text Available Penelitian ini  bertujuan untuk menganalisis pengaruh kemampuan individu, kepuasan kerja, komitmen organisasi terhadap kinerja dan kinerja terhadap kualitas pelayanan. Sampel penelitian berjumlah 76 orang. Teknik pengambilan sampel menggunakan proportional random sampling. Variabel penelitian terdiri dari kemampuan individu, kepuasan kerja, komitmen organisasi, dan kinerja serta kualitas pelayanan  Analisis data menggunakan regresi dua tahap. Hasil penelitian menunjukkan bahwa kemampuan individu, kepuasan kerja dan komitmen organisasi mempunyai pengaruh positif signifikan terhadap kinerja dan kinerja berpengaruh positif signifikan terhadap kualitas pelayanan. Ini berarti semakin meningkat kinerja, maka semakin meningkat juga kualitas pelayanan. Dari hasil analisis deskriptif persentase tampak secara rata-rata  semua variabel penelitian  menunjukkan kategori baik, namun pada aspek-aspek tertentu pada masing-masing variabel masih terdapat kekurangan. Hasil penelitian ini diharapkan dapat menjadi masukan bagi pimpinan dalam meningkatkan kinerja dan kualitas pelayanan. Upaya perbaikan dimulai dari peningkatan kemampuan melalui pendidikan dan latihan, monitoring pelaksanaan kerja secara rutin, menumbuhkan komitmen kerja dan perbaikan standar operasi prosedur.The aim of the study is toanalyze the influence of individual abilities, job satisfaction, organizational commitment to performanceand performance againstservice quality. This samplingmethod is using 76 samples by the proportionalrandom sampling techniques. Variables consisted of individual ability, job satisfaction, organizational commitment, and performance andservice qualitydata analysisusingtwo-stageregression. The results showedthat theability of individuals, job satisfaction and organizational commitment had asignificant positive effecton performance and the performance ofa significant positive effecton quality of service. It means the higher performance, the higher service

  9. Analisis Spektral Daya dan Koherensi EEG Pada Anak Penderita Autism Spectrum Disorders (ASD

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    Nita Handayani

    2017-12-01

    Full Text Available Autism Spectrum Disorders (ASD adalah kondisi neurodevelopmental yang berkaitan dengan defisit dalam fungsi eksekutif, emosi, bahasa, dan komunikasi sosial. Beberapa teknik neuroimaging dan neurofisiologi digunakan untuk memahami hubungan antara fungsionalitas otak dan perilaku autis. Quantitative Electroencephalography (QEEG adalah sebuah teknik non-invasif yang dapat digunakan untuk memberikan gambaran fungsionalitas otak melalui beberapa besaran fisis yang dikaji. Pada paper ini akan dibahas tentang karakteristik sinyal listrik otak pada penderita austis berdasarkan analisis QEEG. Perekaman sinyal otak menggunakan Emotiv Epoc 14 channel (AF3, F7, F3, FC5, T7, P7, O1, O2, P8, T7, FC6, F4, F8, AF4 dan 2 channel referensi (CMS dan DRL. Jumlah subjek uji dalam penelitian sebanyak 6 anak penderita autis dan 5 anak sehat sebagai kontrol dengan rentang usia antara 10-15 tahun. Perekaman otak dilakukan pada kondisi rileks dan mata terutup selama 15 menit. Metode analisis data meliputi pre-processing data EEG untuk menghilangkan noise dan artefak, perhitungan spektral daya menggunakan periodogram Welch, dan analisis konektivitas fungsional otak dengan menghitung besarnya koherensi intra-hemisphere dan inter-hemisphere. Dari hasil studi diperoleh bahwa pada anak autis terjadi peningkatan spektral daya pada pita delta dan penurunan spektral daya pada pita alpha dibandingkan dengan subjek kontrol. Analisis konektivitas fungsional otak pada anak autis menunjukkan nilai koherensi intra-hemisphere dan inter-hemisphere yang lebih rendah pada pita delta dan theta, khususnya pada area frontal. QEEG dapat digunakan untuk karakterisasi sinyal otak pada penderita autis dan membedakannya dari subjek normal. Autism Spectrum disorder (ASD is a neurodevelopmental disorder associated with deficits in executive function, emotions, language, and social communication. Several neuroimaging and neurophysiology techniques are used to understand the relationship between

  10. ANALISIS RASIO ALTMAN MODIFIKASI PADA PREDIKSI KEBANGKRUTAN PERUSAHAAN PROPERTY DAN REAL ESTATE YANG TERDAFTAR DI BEI

    OpenAIRE

    Anita Tri Widiyawati; Supri Wahyudi Utomo; Nik Amah

    2015-01-01

    Penelitian ini bertujuan untuk mengetahui pengaruh rasio Altman Modifikasi terhadap prediksi kebangkrutan. Jenis penelitian ini termasuk penelitian kuantitatif. Populasi dalam penelitian ini adalah perusahaan property dan real estate yang terdaftar di BEI. Teknik pengambilan sampel menggunakan purposive sampling sehingga diperoleh sampel sejumlah 32 perusahaan property dan real estate yang menerbitkan laporan keuangannya selama tahun 2011-2013. Teknik analisis data menggunakan regresi logisti...

  11. ANALISIS KINERJA COOLING TOWER 8330 CT01 PADA WATER TREATMENT PLANT-2 PT KRAKATAU STEEL (PERSERO. TBK

    Directory of Open Access Journals (Sweden)

    Hutriadi Pratama Siallagan

    2017-11-01

    Full Text Available Pada proses produksi baja sangat erat kaitannya dengan pendinginan baik untuk proses pendinginan baja maupun pendinginan mesin-mesin produksi supaya terhindar dari over heat sehingga dapat bekerja dengan optimal. Pada PT Krakatau Steel menggunakan beberapa sistem pendingin salah satunya adalah sistem pendingin cooling tower 8330 CT 01. Sistem pendingin tersebut digunakan untuk menunjang proses produksi dan juga pendinginanan mesin produksi khusunya pada Slab Steel Plant (SSP, dengan peran yang sangat besar maka cooling tower 8330 CT 01 harus diketahui bagaimana kinerjanya. Skripsi ini membahas tentang analisis kinerja Cooling tower 8330 CT 01 dengan membandingkan data teori dengan data aktual berdasarkan perhitungan-perhitungan sehingga dapat diketahui bagaimana kinerja dari Cooling tower 8330 CT 01 tersebut. Dari hasil analisis diperoleh penurunan efisiensi sebesar 22,353%, kapasitas pendinginan 7.033,35 Kj/s, Hal tersebut diakibatkan oleh temperatur air yang masuk Cooling tower 8330 CT 01 tidak terlalu tinggi, karena SSP sedang dalam pengerjaan revitatalisi, agar lebih efektif dan efisien Cooling tower 8330 CT 01 sebaiknya lebih dimamfaatkan lagi untuk pendingin objek lainnya sehingga temperatur air yang masuk tidak terlalu rendah.

  12. ANALISIS GEN HAEMAGGLUTININ PADA VIRUS CAMPAK LIAR

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    Subangkit Subangkit

    2015-05-01

    Full Text Available AbstrakPenyakit Campak disebabkan oleh virus campak yang termasuk genus Morbilivirus dan Family Paramyxoviridae. Penyakit campak masih menjadi masalah kesehatan karena masih ditemukan Kejadian Luar Biasa (KLB di Indonesia. Salah satu penyebab terjadinya KLB tersebut diduga sebagaiakibat perbedaan antigenesitas antara strain vaksin yang digunakan dengan strain virus campak liar yang beredar di Indonesia. Penelitian ini bertujuan mendapatkan gambaran tentang karakteristik genetik gen Haemagglutinin virus campak liar yang ada di Indonesia. Spesimen yang digunakan sebanyak 27 isolat virus penyebab KLB dari 17 propinsi selama periode tahun 2003-2010. Isolat virus dilakukan pemeriksaan secara RT-PCR dan sekuensing dengan metode Sanger. Hasil sekuensing dianalisis dengan menggunakan perangkat lunak Bioedit 7.0 dan MEGA 4.0. Hasil penelitian didapatkan perbedaan 10 asam amino antara virus campak strain vaksin CAM-70 dan virus campak liar pada posisi D416N; K424T; V451M; N455T; V466I; I473T; F476L; Y481S atau Y481N; H495N; G505D. Kesimpulan penelitian ini adalah terdapat perbedaan karakteristik genetik antara virus campak liar di Indonesia berbeda dengan strain virus vaksin CAM-70.Kata kunci : Campak, Analisis Molekuler, Hemagglutinin, CD46AbstractMeasles is caused by virus belonging to the genus Morbilivirus and Family Paramyxoviridae. Measles is still a public health problem because outbreak of measles still found in Indonesia. Outbreak is suspected as a result of differences in antigenicity between vaccine strains used with wild-type measles virus strains circulating in Indonesia. This study aims to get genetic characteristics of wild-type measles virus haemagglutinin gene in Indonesia. The specimens were used 27 viral isolates from 17 provinces period 2003-2010. Viral isolates examined by RT-PCR and sequencing with Sanger method. Sequencing analysis were conducted using Bioedit 7.0 and MEGA 4.0 software. The results showed 10 amino acid differences

  13. Spent fuels conditioning and irradiated nuclear fuel elements examination: the STAR facility and its abilities

    Energy Technology Data Exchange (ETDEWEB)

    Boussard, F.; Huillery, R. [CEA Centre d`Etudes de Cadarache, 13 - Saint-Paul-lez-Durance (France). Dept. d`Etudes des Combustibles; Averseng, J.L.; Serpantie, J.P. [Novatome Industries, 92 - Le Plessis-Robinson (France)

    1994-12-31

    This paper is a presentation of the STAR facility, a high activity laboratory located in Cadarache Nuclear Research Center (France). The purpose of the STAR facility and of the associated processes, is the treatment, cleaning and conditioning of spent fuels from Gas Cooled Reactors (GCR) and in particular of about 2300 spent GCR fuel cartridges irradiated more than 20 years ago in Electricite de France (EDF) or CEA Uranium Graphite GCR. The processes are: to separate the nuclear fuel from the clad remains, to chemically stabilize the nuclear material and to condition it in sealed canisters. An additional objective of STAR consists in non-destructive or destructive examinations and tests on PWR rods or FBR pins in the frame of fuel development programs. The paper describes the STAR facility conceptual design (safety design rules, hot cells..) and the different options corresponding to the GCR reconditioning process and to further research and development works on various fuel types. (J.S.). 3 figs.

  14. Spent fuels conditioning and irradiated nuclear fuel elements examination: the STAR facility and its abilities

    International Nuclear Information System (INIS)

    Boussard, F.; Huillery, R.

    1994-01-01

    This paper is a presentation of the STAR facility, a high activity laboratory located in Cadarache Nuclear Research Center (France). The purpose of the STAR facility and of the associated processes, is the treatment, cleaning and conditioning of spent fuels from Gas Cooled Reactors (GCR) and in particular of about 2300 spent GCR fuel cartridges irradiated more than 20 years ago in Electricite de France (EDF) or CEA Uranium Graphite GCR. The processes are: to separate the nuclear fuel from the clad remains, to chemically stabilize the nuclear material and to condition it in sealed canisters. An additional objective of STAR consists in non-destructive or destructive examinations and tests on PWR rods or FBR pins in the frame of fuel development programs. The paper describes the STAR facility conceptual design (safety design rules, hot cells..) and the different options corresponding to the GCR reconditioning process and to further research and development works on various fuel types. (J.S.). 3 figs

  15. Definitive Radiotherapy of Non-Small Cell Lung Cancer

    International Nuclear Information System (INIS)

    Lee, Jong Young; Park, Kyung Ran

    1995-01-01

    Purpose : The effect of dose escalation of up to 6500 cGy on local control and survival was investigated in locally advanced non-small cell lung cancer. Materials and Methods : Ninety eight patients with biopsy-proven unresectable non-small cell lung cancer without distant metastases or medically inoperable patients with lower-stage were treated with definitive radiotherapy alone. Group A were treated by thoracic irradiation, 6000 cGy or less in total tumor dose with daily fractions of 180 to 200 cGy: and group B was treated with 6500 cGy of same daily fractions. Results : The actuarial overall survival rate for the entire group was 54% at 1 year, 26.6% at 2 years and 16.4% at 3 years with a median survival time of 13 months. Statistically significant prognostic factors that affect survival rate were stage and N-stage. However, no improvement in local control and survival has been seen with higher dose radiotherapy(group B). Conclusion : Dose escalation of up to 6500 cGy was no effect on local control and survival rate. To increase the survival rate of non-small cell lung cancer hyperfractionated radiotherapy or concurrent chemoradiotherapy should be considered

  16. Evaluation of ductile tearing in a cracked component with a simple method (Js)

    International Nuclear Information System (INIS)

    Moulin, D.; Drubay, B.; Clement, G.; Nedelec, M.

    1995-01-01

    In the nuclear industry, it is more and more usual to perform fracture assessment on detective structures made of ductile material with the help of elastoplastic' fracture mechanics relying on the parameter J. Several engineering methods have been developed in the past to calculate this parameter. These results were used to develop a practical procedure noted Js method which simply gives J as function of elastically calculated Je and a plastic correction factor. This method has been introduced in the A16 rule developed jointly by CEA-EdF and Novatome for fast breeder reactors in particular in order to evaluate the loading at crack instability taking into a account ductile tearing. The determination of initiation has already been presented. This determination of the loading at crack instability is examined through two simple but representative examples using the simplified estimation of J. Predicted loadings at crack instability are compared with experimental results. This study was carried out a part of cooperative program with the Institut de Protection et de Surete Nucleaire of the CEA. (author) 12 refs., 10 figs

  17. ANALISIS PENGGUNAAN FILTER AKTIF SHUNT UNTUK MENANGGULANGI THD DI RSUP SANGLAH

    Directory of Open Access Journals (Sweden)

    I Wayan Rinas

    2009-12-01

    Full Text Available Rumah Sakit Umum Pusat Sanglah (RSUP memiliki tingkat THD (Total Harmonics Distortion  arus yang tidak sesuai dengan standar IEEE 159-1992. THD arus yang berlebih dapat menyebabkan berbagai kekurangan. Untuk mengatasi masalah ini digunakan filter aktif shunt berbasis inverter. Dalam penelitian ini dilakukan simulasi penggunaan filter aktif menggunakan sofware simulink MATLAB 7.0.4 Hasil analisis menunjukan pemasangan filter aktif menyebabkan terjadi penurunan kandungan THD arus dan THD tegangan pada feeder yang bermasalah. Kandungan THD arus dan THD tegangan telah sesuai dengan IEEE 152-1992. Daya distorsi harmonisa pada sistem mengalami penurunan dan terjadi peningkatan faktor daya mendekati unity power factor pada feeder.

  18. ANALISIS PENJUALAN LEMARI ES MEREK LG PADA PT. LG ELECTRONICS INDONESIA CABANG PEKANBARU

    Directory of Open Access Journals (Sweden)

    Hadiyati Hadiyati

    2015-04-01

    Full Text Available Abstrak: PT. LG Electronics Indonesia Cabang Pekanbaru merupakan salah satu perusahaan perdagangan yang menjual berbagai macam produk elektronik termasuk  Lemari Es. Penelitian ini bertujuan untuk: (1. Mengetahui penjualan yang dilakukan oleh manajemen PT. LG Electronics Indonesia Cabang Pekanbaru. (2. Mengetahui faktor-faktor yang menyebabkan tidak tercapainya target penjualan Lemari Es Merek LG Pada PT. LG Electronics Indonesia Cabang Pekanbaru. Populasi dalam penelitian ini adalah keseluruhan dari objek yaitu seluruh konsumen Lemari Es merek LG pada PT. LG Electronics Indonesia Cabang Pekanbaru pada tahun 2013 yaitu sebanyak 8.563 orang. Karena keterbatasan penulis, maka diambil sampel yang dianggap mewakili pelanggan yaitu sebanyak 100 orang dengan rumus slovin. Analisis data dilakukan dengan menggunakan metode Analisis Deskriptif. Variabel yang digunakan adalah produk, harga, dan promosi. Berdasarkan hasil penelitian diperoleh, tidak tercapainya target penjualan Lemari Es merek LG pada PT. LG Electronics Indonesia Cabang Pekanbaru karena produk yang ditawarkan belum sepenuhnya sesuai dengan keinginan dan harapan konsumen, harga yang ditawarkan belum sepenuhnya sesuai dengan kondisi ekonomi masyarakat secara umum, serta promosi yang belum maksimal. Abstract: PT. LG Electronics Indonesia Branch of Pekanbaru is one trading company that sells a wide range of electronic products including Refrigerator. This study aims to: (1. Knowing the sales made by the management of PT. LG Electronics Indonesia Branch of Pekanbaru. (2. Knowing the factors that leads failure to achieve sales targets Refrigerator Brand LG At PT. LG Electronics Indonesia Branch of Pekanbaru. The population in this study is the whole of the object that is the entire consumer Refrigerator LG brand in the PT. LG Electronics Indonesia Pekanbaru Branch in 2013 as many as 8563 people. Because of the limitations of the author, then a swab which is considered to represent the customer

  19. Nonlinear analysis of thermal stresses of a of first stage nozzle of a gas turbine at full load from the results of an analysis of conjugated heat transference; Analisis no lineal de esfuerzos termicos de una tobera de primera etapa de turbina de gas a plena carga a partir de resultados de un analisis de transferencia de calor conjugado

    Energy Technology Data Exchange (ETDEWEB)

    Perez Hernandez, Efrain [Centro Nacional de Investigacion y Desarrollo Tecnologico (Cenidet), Cuernavaca, Morelos (Mexico); Mazur C, Zdzislaw; Garcia Illescas, R; Hernandez Rossette, Alejandro [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

    2007-11-15

    The gas turbines operate at extremely high temperatures, at high thermal and mechanical stresses, causing that the useful life of the involved components be reduced. In the present article the results realized by previous investigations of temperatures obtained from analysis of heat transfer and flow of fluids of the nozzle by means of the Star-CD program based on finite volumes is presented. Later, the NISA program of finite elements was used to realize the analysis of thermal stresses considering the material plasticity. The methodology employed to determine the material properties variable with the temperature of the super-alloy FSX-414 and the plasticity model used in the structural analysis in the finite element program. The result will be later used in the fatigue analysis for the useful life assessment. [Spanish] Las turbinas de gas operan a temperatura extremadamente altas, a elevados esfuerzos termicos y mecanicos, ocasionando que la vida de los componentes involucrados se reduzca. En el presente articulo se presentan los resultados realizados por previas investigaciones de temperaturas obtenidas a partir de analisis de transferencia de calor y flujo de fluidos de la tobera mediante el programa Star-CD basado en volumenes finitos. Posteriormente, se utilizo el programa NISA de elementos finitos para realizar el analisis de esfuerzos termicos considerando plasticidad del material. Se muestra la metodologia empleada para determinar las propiedades del material variables con la temperatura de la superaleacion FSX-414 y el modelo de plasticidad utilizado en el analisis estructural en el programa de elemento finito. Los resultados seran empleados posteriormente en el analisis de fatiga para la estimacion de vida util.

  20. Kajian Eksperimental Parameter Modal Bangunan Dua Lantai dengan Metode Modal Analisis

    Directory of Open Access Journals (Sweden)

    Islahuddin Islahuddin

    2016-12-01

    Full Text Available Abstrak: Pengukuran getaran merupakan kegiatan yang umum dilakukan dalam perawatan prediktif. Perawatan prediktifbiasanya menggunakan pengukuran sinyal getaran untuk mendeteksi kerusakan yang terjadi pada mesin. Sinyalgetaran yang terukur tersebut, kemudian ditransformasikan dalam bentuk grafik fungsi respon frekuensi (FRF.Selanjutnya FRF diolah sedemikian rupasehingga diperoleh modus getar struktur. Dari modus getar yang diperoleh,maka dapat dianalisa kemungkinan kerusakan yang terjadi pada mesin dengan melihat besarnya amplitudo getarannya.Penelitian ini bertujuan untuk menganalisa karakteristik dinamik dari sistem getaran yang terjadi pada model strukturbangunan dua lantai. Pengujian dilakukan denganmemberikan gaya eksitasi menggunakan impact hammer.Akselerometer digunakan mengukur sinyal getaran yang terjadi pada struktur. Posisi penempatan akselerometerdilakukan bervariasi untuk delapan titik pengujian yang berbeda. Sedangkan posisi pemberian gaya eksitasi tetap untuksemua titik pengujian. Pada penelitian ini menggunakan metode modal analisis eksperimen untuk mengetahuikarakteristik dinamik dari model struktur bangunan dua lantai. Teknik modal analisis ini digunakan untuk mendapatkanparameter modal seperti frekuensi, rasio redaman, dan modus getar. Hasil yang diperoleh dari penelitian inimenunjukkan bahwafrekuensi pribadipertama pada amplitudo maksimum mempunyai nilai yang sama, yaitu 2,313 Hz.Sedangkan untuk frekuensi pribadi kedua pada amplitudo maksimumnya terdapat perbedaan, yaitu pada titik pengujian3 dan 7. Hal ini dapat disebabkan oleh pemberian gaya eksitasi yang tidak sama dengan titik-titik pengujian yang lain.Kata kunci: Karakteristik dinamik, analisis modal eksperimen, frekuensi pribadi, FRF Abstract: Measuring vibration is an activity which is generally carried out in a predictive maintenance. In maintaining, vibratesignal measurement is usually used for machine damage detection. The signal measurement is then being

  1. Penggunaan Kontrasepsi pada Remaja Perempuan Kawin di Indonesia (Analisis Riskesdas 2013

    Directory of Open Access Journals (Sweden)

    Anissa Rizkianti

    2017-12-01

    Full Text Available AbstractAdolescent pregnancy has been highlighted in various parts of the world including access to contraceptive use among married teenagers. This is an advanced analysis of secondary data of Riskesdas 2013 that aims to identify contraceptive use among married adolescents in Indonesia. The data used in multilevel logistic regression analysis consist of demographic characteristics of adolescents, parity, availability of health services and the use of health insurance.. The results showed that 54.2% of married adolescents women or their partners used any method of contraception. Age, education level, socioeconomic status and the use of health insurance have significant relationships to contraceptive use after adjusted by the type of residence, parity and availability of health services. Adolescent aged above 17 years (OR=1.49, 95% CI 1.25 to 1.79 and had higher socio-economic status (OR kuintil 5=1.62, 95% CI 1,19- 2.22 were more likely to use contraception, while young women with higher school education (OR= 0.73; 95% CI .58-.91 as well as used health insurance (OR=0.72; 95 % CI 0.60 to 0.86 had smaller probability in contraceptive use. Fulfillment of adolescent access to contraception is expected to focus not only on increasing of knowledge but also purchasing power, which is through the utilisation of health insurance.Key words: contraception, married adolescents, RiskesdasAbstrakKehamilan remaja telah menjadi sorotan di berbagai belahan dunia, termasuk akses terhadap penggunaan kontrasepsi pada remaja kawin. Studi ini merupakan analisis lanjut Riskesdas 2013 untuk mengetahui penggunaan kontrasepsi pada remaja kawin di Indonesia. Data yang digunakan dalam analisis regresi logistik multi level terdiri atas karakteristik demografi remaja, paritas, ketersediaan pelayanan kesehatan serta penggunaan jaminan kesehatan. Subjek adalah seluruh remaja perempuan berusia 15-19 tahun yang berstatus kawin dan aktif secara seksual. Hasil menunjukkan bahwa

  2. KERAGAAN WARNA IKAN CLOWN BIAK (Amphiprion percula) POPULASI ALAM DAN BUDIDAYA BERDASARKAN ANALISIS GAMBAR DIGITAL

    OpenAIRE

    Ruby Vidia Kusumah; Sawung Cindelaras; Anjang Bangun Prasetio

    2015-01-01

    Penelitian ini bertujuan untuk mengkaji keragaan warna ikan clown Biak (Amphiprion percula) populasi alam dan budidaya berdasarkan analisis gambar digital sebagai dasar upaya pemuliaannya. Gambar digital diambil dari koleksi ikan clown Biak Balai Besar Perikanan Budidaya Laut Lampung, Balai Besar Penelitian dan Pengembangan Budidaya Laut Gondol, Bali; serta pengumpul ikan hias di Denpasar, Bali menggunakan kamera digital Canon EOS 600D. Pola warna dikarakterisasi secara visual terhadap varias...

  3. ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI LOYALITAS PELANGGAN DAN DAMPAKNYA TERHADAP KEUNGGULAN BERSAING (STUDI PADA BMT AMANAH UMMAH SUKOHARJO

    Directory of Open Access Journals (Sweden)

    meyta pritandhari

    2015-05-01

    Full Text Available Abstrak   Baitul Maal Wat Tamwil merupakan salah satu model lembaga keuangan syariah yang saat ini banyak muncul di Indonesia. BMT Amanah Ummah memiliki 9.142 anggota dan 45 % anggotanya tidak loyal kepada BMT. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi loyalitas pelanggan dan dampaknya terhadap keunggulan bersaing. Penelitian ini menggunakan metode penelitian deskriptif dengan pendekatan analisis kualitatif dengan model analisis interaktif. Teknik sampling yang digunakan adalan insidental sampling untuk anggota BMT dan purposive sampling  untuk  pimpinan, manajer dan  marketing.  Teknik  pengumpulan  data yang digunakan yaitu wawancara, observasi dan dokumentasi. Hasil penelitian ini menunjukkan bahwa dari beberapa faktor yang mempengaruhi loyalitas pelanggan yaitu reputasi merek, kepuasan angggota, kualitas pelayanan, kualitas pelayanan berpengaruh positif terhadap kepuasan anggota, dan kualitas pelayanan. Dari beberapa faktor tersebut faktor kualitas pelayanan yang paling dominan dalam mempengaruhi loyalitas anggota.Dampak loyalitas terhadap keunggulan bersaing dapat dilihat dari seberapa banyak anggota BMT yang tidak pindah ke lembaga keuangan lain. Semakin bagus kualitas pelayanan maka semakin tinggi tingkat loyalitas dan keunggulan bersaing antar lembaga keuangan juga semakin tinggi.

  4. ANALISIS PENERAPAN PRINSIP MENGENAL NASABAH PADA BANK ACEH SYARIAH BANDA ACEH

    Directory of Open Access Journals (Sweden)

    Husnawati Husnawati

    2013-06-01

    Full Text Available This study aims to identify the systems and procedures that is applied at Bank Aceh Syariah (BAS Banda Aceh in knowing of its customers. In specific, it aims to analyze the effectiveness of the implementation of Knowing Your Customer (KYC Principle at BAS. This study employs both primary and secondary data which was obtained through field and library research. The data was analyzed using descriptive analysis method. The results show that in knowing its customers, BAS Banda Aceh taken several steps of customer identification includes the identity check, occupation, source of funds, and the purpose of the use of funds. The implementation of the KYC principle in BAS Banda Aceh has effectively overcome and prevented the banking crimes such as money laundering. The implementation of the principle is intended to embolden the implementation of prudential principles in order to reduce business risks such as operational risk, legal risk, concentration risk, and reputational risk. =========================================== Penelitian ini bertujuan untuk mengidentifikasi sistem dan prosedur yang diterapkan Bank Aceh Syariah (BAS Banda Aceh dalam mengenal nasabah. Secara khusus, penelitian bertujuan untuk menganalisis efektifitas penerapan Prinsip Mengenal Nasabah pada BAS. Data untuk penelitian ini bersumber dari data primer melalui kajian lapangan, dan data sekunder melalui kajian kepustakaan. Analisis data menggunakan metode deskriptif analisis. Dari hasil penelitian dapat diketahui bahwa sistem dan prosedur yang diterapkan BAS Banda Aceh dalam mengenal nasabah yaitu identifikasi calon nasabah yang meliputi identitas, pekerjaan, sumber dana dan tujuan penggunaan dana yang dilengkapi dokumen pendukung. Penerapan Prinsip Mengenal Nasabah (Know Your Customer Principle pada BAS Banda Aceh efektif dalam mengatasi kejahatan-kejahatan dalam dunia perbankan seperti pencucian uang. Penerapan prinsip tersebut dimaksudkan agar mendorong terselenggaranya prinsip

  5. PESAN MORAL DALAM FILM TO KILL A MOCKINGBIRD (ANALISIS SEMIOTIKA PADA FILM TO KILL A MOCKINGBIRD

    OpenAIRE

    RENYOET, JAQUILINE MELISSA

    2014-01-01

    2014 JAQUILINE MELISSA RENYOET. Pesan Moral Dalam Film To Kill A Mockingbird (Analisis Semiotika Pada Film To Kill A Mockingbird). (Dibimbing oleh Muh. Nadjib dan Alem Febri Sonni). Tujuan Penelitian ini adalah mengidentifikasi bentuk pesan moral dan memahami makna pesan moral dalam film To Kill A Mockingbird. Penelitian ini dilakukan selama kurang lebih 2 bulan yaitu Maret ??? Mei 2014. Metode yang digunakan untuk penelitian ini adalah metode penelitian kualitatif den...

  6. Analisi Pengaruh Store Name, Brand Name, Dan Price Discounts Terhadap Purchase Intentions Konsumen Infinite Tunjungan Plaza

    OpenAIRE

    Gunawan, Andy

    2013-01-01

    Andy Gunawan:SkripsiAnalisis pengaruh store name, brand name dan price discounts terhadap purchase intention konsumen infnite tunjungan plaza Di era globalisasi ini, persaingan dagang antara Perusahaan – Perusahaan baik lokal maupun global menjadi semakin ketat, oleh karena itu Perusahaan selalu berusaha untuk meningkatkan ketertarikan minat beli konsumen. Beberapa variabel yang menjadi fokus Perusahaan adalah store name, brand name, dan price discount. Tujuan penelitian ini adalah untuk meng...

  7. Keefektifan Konseling Behavioral Teknik Modeling dan Konseling Analisis Transaksional Teknik Role Playing untuk Meminimalkan Kecenderungan Perilaku Agresif Siswa Sekolah Menengah Atas

    Directory of Open Access Journals (Sweden)

    I Ketut Gading

    2017-11-01

    Full Text Available Abstract: This study aims to determine the effectiveness of behavioral counseling using modeling technique and counseling transactional analysis using role playing technique to minimize student’s tendency of aggressive behavior. This experimental research with pretest-posttest control group design is taking samples using purposive sampling technique. The sample were 18 tenth grade students from Senior High School Laboratorium Universitas Pendidikan Ganesha who have high aggressive behavior. 18 sample were randomly assigned to three group, that is: (1 experimental group of behavioral counseling using modeling technique; (2 counseling transactional analysis using role playing technique group; and (3 control group. Data on aggressive behavior tendency before and after treatment were collected using questionnaire of aggressive behavior, then analyzed by t test. The results show: (1 behavioral counseling using modeling technique were effective to minimize the tendency of aggressive behavior; (2 counseling transactional analysis using role playing technique were effective to minimize the aggressive behavior; and (3 counseling transactional analysis using role playing technique were more effectively minimizes the tendency of aggressive behavior rather than behavioral counseling using modeling technique. Abstrak: Penelitian ini bertujuan untuk mengetahui keefektifan konseling behavioral teknik modeling dan konseling analisis transaksional teknik role playing untuk meminimalkan kecenderungan perilaku agresif siswa. Penelitian eksperimen dengan rancangan pretest-posttest control group design ini mengambil sampel dengan teknik purposive sampling. Sampel terdiri dari 18 orang siswa kelas X Sekolah Menengah Atas (SMA Laboratorium Universitas Pendidikan Ganesha yang memiliki perilaku agresif tinggi. 18 sampel dibagi secara acak dan merata pada tiga kelompok, yaitu: (1 kelompok eksperimen yang mendapatkan perlakuan konseling behavioral teknik modeling; (2

  8. Analisis Migrasi Radio Trunking Analog ke Radio Trunking Digital di Indonesia

    Directory of Open Access Journals (Sweden)

    Riza Azmi

    2013-09-01

    Full Text Available Dalam Tabel Alokasi Spektrum Frekuensi di Indonesia pada catatan kaki INS9 dan INS13 disebutkan bahwa alokasi pada pita-pita frekuensi yang digunakan untuk teknologi trunking direncanakan dimigrasi ke sistem komunikasi trunking digital pada waktu yang akan ditentukan oleh pemerintah. Terkait dengan hal itu, studi ini bertujuan untuk mengkaji bagaimana kelayakan migrasi dari sistem trunking analog ke sistem trunking digital dan hal-hal yang terkait dengannya. Dengan menggunakan analisis biaya dan manfaat (Cost-Benefit Analysis studi ini melihat bahwa migrasi hanya dapat dilakukan jika umur masing-masing lisensi dari operator telah berakhir, atau dengan kata lain pemerintah dapat mendorong transisi ke digital dengan menerbitkan lisensi baru yaitu lisensi trunking digital.

  9. RASISME DALAM FILM 99 CAHAYA DI LANGIT EROPA PART 1 (ANALISIS SEMIOTIKA DALAM FILM 99 CAHAYA DI LANGIT EROPA PART 1

    Directory of Open Access Journals (Sweden)

    Vallen Nur Rita

    2016-09-01

    Full Text Available Stereotip merupakan pernyataan negatif dari prasangka. Prasangka inilah yang kemudian dijadikan alasan untuk melakukan diskriminasi terhadap kelompok rasial tertentu. Stereotip dan prasangka kemudian merujuk pada suatu paham yang mempercayai adanya superioritas yang menolak adanya kesetaraan manusia yaitu rasisme. Perilaku maupun tindakan rasisme tersebut banyak muncul dalam beberapa scene film 99 Cahaya Di Langit Eropa Part 1. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana simbol-simbol digunakan untuk menggambarkan rasisme di dalam film 99 Cahaya Di Langit Eropa Part 1. Metode yang digunakan oleh peneliti adalah semiotika Roland Barthes. Model Roland Barthes terdiri dari tiga tahap analisis yaitu denotasi, konotasi, mitos. Peneliti melakukan analisis menggunakan tanda verbal dan nonverbal yang terdapat dalam film “99 Cahaya di Langit Eropa Part 1”. Dalam menganalisis film 99 Cahaya di Langit Eropa Part 1, dikelompokkan menjadi beberapa kategori yang berhubungan dengan perilaku rasisme, antara lain : stereotip, prasangka, diskriminasi

  10. Development of an analytic outline for the aflatoxins analysis in grains and flours; Desarrollo de un esquema analitico para el analisis de aflatoxinas en granos y harinas

    Energy Technology Data Exchange (ETDEWEB)

    Sibaja Adams, Roxana

    2000-07-01

    The instrumental and analytic conditions were optimized for the aflatoxine determination B1, B2, 1 and G2 in corn and peanut byl iquid chromatography of high discharge following the analyzing method AOAC 994,08. Besides, it was defined a function for evaluating the dependence of the chromatographic discharge with the aflatoxine concentration. The analyzing method was validated, and four calibration curves were obtained for the aflatoxine B1, B2, G1 and G2, which turned to have a heterocedastico behavior. The applicability of this method was demonstrated, obtaining imagines of appropriate merit and comparable with those reported by the AOAC. Additionally, the applicability of the chromatographic method was demonstrated in fine layer for the presumptive analysis of aflatoxine, allowing both methods to propose an outline of reliable analysis of real samples. [Spanish] Se optimizaron las condiciones instrumentales y analiticas para la determinacion de aflatoxinas B1, B2, G1 y G2 en maiz y mani por Cromatografia liquida de alto desempeno siguiendo el metodo de analisis AOAC 994,08. Ademas, se definio una funcion para evaluar la dependencia del desempeno cromatografico con la concentracion de aflatoxinas.Se valido el metodo de analisis y se obtuvieron las cuatro curvas de calibracion para las aflatoxinas B1, B2, G1 y G2, las que resultaron tener un comportamiento heterocedastico. Se demostro la aplicabilidad del metodo, obteniendose figuras de merito adecuadas y comparables con las reportadas por el AOAC.Adicionalmente, se demostro la aplicabilidad del metodo de cromatografia en capa fina para el analisis presuntivo de aflatoxinas, permitiendo ambos metodos proponer un esquema de analisis confiable de muestras reales.

  11. Analisis Plagiat dalam Penulisan Laporan Ilmiah Kelas XI Smk Sakti Gemolong Kabupaten Sragen Tahun Ajaran 2015/2016

    OpenAIRE

    Sari, Dwi Ratna; Arfa, Mecca

    2016-01-01

    Penelitian ini berjudul “Analisis Plagiat dalam Penulisan Laporan Ilmiah Kelas XI SMK Sakti Gemolong Kabupaten Sragen Tahun Ajaran 2015/2016”. Tujuan dari penelitian ini adalah untuk mengetahui pemahaman siswa mengenai tindakan plagiat, serta menganalisis tipe-tipe plagiat dan faktor-faktor yang menyebabkan tindakan plagiat. Penelitian ini menggunakan desain penelitian kualitatif dengan jenis penelitian studi kasus. Teknik pengambilan sampel pada penelitian ini menggunakan purposive sampling....

  12. ANALISIS PENERAPAN STRATEGI PEMASARAN DALAM PENINGKATAN PANGSA PASAR PADA PT. HADJI KALLA (TOYOTA) CABANG COKROAMINOTO DI MAKASSAR

    OpenAIRE

    ASTRINI, PRATANTI AYU

    2007-01-01

    Analisis Penerapan Strategi Pemasaran Dalam Peningkatan Pangsa Pasar Pada PT. Hadji Kalla (Toyota) Cabang Cokroaminoto di Makassar Implementation of marketing strategy analyze on increasing market share study case PT.Hadji Kalla (Toyota) Cabang Cokroaminoto in Makassar Pratanti Ayu Astrini Mursalim Nohong Wardhani Hakim Tujuan dari penelitian ini adalah untuk mengetahui penerapan strategi pemasaran mobil Toyota pada PT. Hadji Kalla (Toyota) Cabang Cokroaminoto di Makassar me...

  13. ANALISIS POSISI RECLOSER TERHADAP KEANDALAN KINERJA PENYULANG SEMPIDI BERBASISKAN SOFTWARE ETAP POWERSTATION

    Directory of Open Access Journals (Sweden)

    I Nengah Sunaya

    2017-11-01

    Full Text Available Penelitian ini menganalisis koordinasi recloser yang terdapat pada penyulang Sempidi untuk meningkatkan keandalan kinerja dari penyulang tersebut. Keandalan yang diharapkan adalah keandalan dalam penyediaan dan penyaluran dayanya. Untuk mengetahui keandalan dalam penyaluran tenaga listrik kepada konsumen perlu diperhitungkan indeks keandalannya. Indeks keandalan menjadi indikator dinyatakan dalam suatu besaran probabilitas yang bertujuan meminimalkan nilai SAIDI dan SAIFI, yaitu 1,8805505 jam/pelanggan tahun dan 5,8200455 kegagalan/pelanggan tahun, serta nilai fitness sebesar 0,091366843 untuk recloser pada posisi 10. Teknik yang digunakan dalam evaluasi keandalan sistem distribusi yaitu metode analisis dengan formula SAIDI dan SAIFI serta metode simulasi dengan memanfaatkan software ETAP powerstation

  14. ANALISIS BAHASA GAUL ANTAR TOKOH DALAM FILM REMAJA INDONESIA “RADIO GALAU FM”

    Directory of Open Access Journals (Sweden)

    St. Victor Maruli tua Lumbantobing , S.Pd., M.Pd

    2016-03-01

    Full Text Available ABSTRAKGajala bahasa ialah segala peristiwa yang berkaitan dengan bentuk-bentukkata beserta proses pembentuknya. Gejala-gejala bahasa seringkali digunakanoleh penutur bahasa baik di dalam film dan masyarakat. Bahasa gaul salah satu gaya bahasa yang sering digunakan anak remaja jaman sekarang. Film Remaja Indonesia yang berjudul “Radio Galau FM” merupakan sebuah karya yangditulis oleh Haqi Achmad. Dalam film ini banyak proses pembentukan kata bahasagaul. Mengingat pentingnya bahasa gaul sebagai wujud produk remaja, makapeneliti tertarik untuk meneliti pembentukan bahasa gaul ini. Sesuai denganrumusan masalah maka penelitian ini dimaksudkan untuk mendeskripsikanproses pembentukan bahasa gaul, yang meliputi: 1 proses afiksasi; 2; gejalagejalabahasa dan 3, serta penggunaan jenis-jenis makna dalam bahasagaul. Untuk membahas masalah tersebut, maka dalam menganalisis, penelitimenggunakan teori pembentukan kata ( kajian Morfologi . Penelitian inimenggunakan jenis penelitian kualitatif. Sedangkan metode yang digunakanadalah metode dan ekstralingual dan teknik analisis data dalam penelitian iniberupa urai unsure langsung dan teknik ubah ujud. Data penelitian ini adalahdialog dalam film “Radio Galau FM” ( berbentuk proses afiksasi, gejala-gejalabahasa, dan jenis-jenis makna. Sumber data berupa rekaman dialog film yangterjadi dalam film “Radio Galau FM”. Secara garis besar hasil analisis datadalam penelitian bahasa gaul sangat berbeda dengan penggunaannya dalam bahasa baku bahasa Indonesia. Hasil yang diperoleh dalam penelitian ini menunjukkan bahwa, bahasa gaul merupakan produk dari remaja, maksudnyaadalah remaja dalam berkomunikasi sehari-hari menggunakan bahasa ini disetiap situasi tanpa memperhatikan keadaan dan situasi, jika dibiarkan makasikap kesopanan akan terabaikan.Kata-Kata Kunci: Pembentukan Kata, Bahasa Gaul, Film Remaja Indonesia.Key words : Formation of words , language Gaul , Youth Film Indonesia

  15. ANALISIS POSTUR KERJA PADA PT. XYZ MENGGUNAKAN METODE ROSA (RAPID OFFICE STRAIN ASSESSMENT

    Directory of Open Access Journals (Sweden)

    Rosma Hani Damayanti

    2014-06-01

    Full Text Available Penggunaan teknologi informasi, dimana komputer sebagai medianya kini semakin meningkat. Frekuensi yang tinggi akan penggunaan komputer yang tidak memperhatikan sisi ergonomi dalam bekerja mengakibatkan adanya resiko yang dirasakan oleh pengguna. PT. XYZ merupakan salah satu perusahaan yang menggunakan komputer sebagai salah satu alat utama dalam bekerja. Pada penggunaannya karyawan pada Departemen Publishing merasakan keluhan pada punggung, pinggang, nyeri bahu, leher dan tangan. Keluhan yang dirasakan oleh pekerja pada Departemen publishing dapat diminimalkan dengan cara mengetahui dan mengidentifikasi postur kerja pada pekerja dalam menggunakan komputer. Identifikasi tersebut digunakan untuk mengetahui kondisi pekerja dan mengetahui penyebab keluhan yang dirasakan oleh pekerja untuk dilakukan perbaikan. Pada penelitian ini dilakukan analisis dengan menggunakan metode ROSA untuk mengurangi adanya keluhan yang dirasakan oleh pekerja pada Departemen publishing. ROSA merupakan salah satu metode pada office ergonomics, dimana penilaiannnya dirancang untuk mengukur resiko yang terkait dengan penggunaan komputer serta untuk menetapkan tingkat tindakan perubahan berdasarkan laporan dari ketidaknyamanan pekerja. Dengan menggunakan metode ROSA, dapat diketahui apakah postur kerja karyawan pada Departemen Publishing pada saat bekerja aman atau berbahaya. Hasil analisis postur kerja menggunakan metode ROSA pada Departemen Publishing menunjukkan bahwa seluruh pekerja yang menjadi sampel memiliki level resiko yang tinggi dan perlu dilakukan perbaikan segera. Perbaikan yang dapat dilakukan untuk mengurangi tingkat resiko yang dirasakan oleh pekerja yaitu dengan perbaikan fasilitas yang digunakan oleh pekerja yang sesuai dengan standar ergonomi, melakukan sosialisasi kepada pekerja tentang pentingnya ergonomi pada dunia kerja, dan sebaiknya pekerja melakukan istirahat atau peregangan otot minimal setiap tiga jam sekali.

  16. ANALISIS POSTUR KERJA PADA PT. XYZ MENGGUNAKAN METODE ROSA (RAPID OFFICE STRAIN ASSESSMENT

    Directory of Open Access Journals (Sweden)

    Rosma Hani Damayanti

    2014-06-01

    Full Text Available Penggunaan teknologi informasi, dimana komputer sebagai medianya kini semakin meningkat. Frekuensi yang tinggi akan penggunaan komputer yang tidak memperhatikan sisi ergonomi dalam bekerja mengakibatkan adanya resiko yang dirasakan oleh pengguna. PT. XYZ merupakan salah satu perusahaan yang menggunakan komputer sebagai salah satu alat utama dalam bekerja. Pada penggunaannya karyawan pada Departemen Publishing merasakan keluhan pada punggung, pinggang, nyeri bahu, leher dan tangan. Keluhan yang dirasakan oleh pekerja pada Departemen publishing dapat diminimalkan dengan cara mengetahui dan mengidentifikasi postur kerja pada pekerja dalam menggunakan komputer. Identifikasi tersebut digunakan untuk mengetahui kondisi pekerja dan mengetahui penyebab keluhan yang dirasakan oleh pekerja untuk dilakukan perbaikan. Pada penelitian ini dilakukan analisis dengan menggunakan metode ROSA untuk mengurangi adanya keluhan yang dirasakan oleh pekerja pada Departemen publishing. ROSA merupakan salah satu metode pada office ergonomics, dimana penilaiannnya dirancang untuk mengukur resiko yang terkait dengan penggunaan komputer serta untuk menetapkan tingkat tindakan perubahan berdasarkan laporan dari ketidaknyamanan pekerja. Dengan menggunakan metode ROSA, dapat diketahui apakah postur kerja karyawan pada Departemen Publishing pada saat bekerja aman atau berbahaya. Hasil analisis postur kerja menggunakan metode ROSA pada Departemen Publishing menunjukkan bahwa seluruh pekerja yang menjadi sampel memiliki level resiko yang tinggi dan perlu dilakukan perbaikan segera.  Perbaikan yang dapat dilakukan untuk mengurangi tingkat resiko yang dirasakan oleh pekerja yaitu dengan perbaikan fasilitas yang digunakan oleh pekerja yang sesuai dengan standar ergonomi, melakukan sosialisasi kepada pekerja tentang pentingnya ergonomi pada dunia kerja, dan sebaiknya pekerja melakukan istirahat atau peregangan otot minimal setiap tiga jam sekali.

  17. Teori Pecking Order dan Trade-Off dalam Analisis Struktur Modal di Bursa Efek Indonesia

    Directory of Open Access Journals (Sweden)

    D Agus Harjito

    2014-06-01

    Full Text Available AbstractThis study aims to test the pecking order theory and trade-off theory of capital structure in the analysis of the Indonesia Stock Exchange. Pecking order theory is represented by the variable profitability and growth, while the variables volatility of earnings, tangibility of assets and the size represents a trade-off theory. The company's goal is prosperity of shareholder value. To achieve these objectives the company needs funds from internal sources and external sources. Internal sources in the form of retained earnings, while the external sources of debt and shareholders' approval in the pecking order theory. This study uses the data of financial ratios of the firms during the period 2000-2010. To analyze the data, this study uses a multiple regression with the dependent variable is the debt ratio, while profitability, growth, volatility of earnings, tangibility of assets and size as independent variables. The results show that asset structure and company size has a positive and significant impact on capital structure, while profitability has a negative effect on debt ratios. But company's growth rate has not relationship with the debt ratio or capital structure. Simultaneously, the all independent variables affect capital structure significantly.Keywords: pecking order, trade-off, capital structure, debt rasioAbstrakPenelitian ini bertujuan untuk menguji teori pecking order dan teori trade-off dalam analisis struktur modal di Bursa Efek Indonesia. Teori pecking order diwakili oleh variabel profitability dan growth, sementara variabel-variabel volatility of earnings, tangibility of assets dan size mewakili teori trade-off. Tujuan perusahaan adalah memakmurkan nilai pemegang saham. Untuk mencapai tujuan tersebut perusahaan membutuhkan dana yang diperoleh dari sumber internal dan sumber eksternal. Sumber internal berupa laba ditahan, sedangkan sumber eksternal berupa hutang dan saham sebagaimana dijelaskan dalam teori pecking order

  18. USULAN STRATEGI UNTUK MENINGKATKAN DAYA SAING PRODUK MEBEL ROTAN SINGLE CHAIR DENGAN ANALISIS RANTAI NILAI (Studi Kasus : Klaster Mebel Rotan Kab. Cirebon

    Directory of Open Access Journals (Sweden)

    Ary Arvianto

    2013-06-01

    Full Text Available Industri mebel rotan merupakan salah satu andalan sektor industri di Indonesia dimana sentra pengolahan rotan terbesar adalah di Kabupaten Cirebon, Jawa Barat. Namun, terdapat beberapa kendala dalam industri mebel rotan di Cirebon ini diantaranya semakin ketatnya persaingan antar produsen dunia dan kebijakan pemerintah memperbolehkan ekspor rotan yang menyebabkan keuntungan di pihak negara pesaing Oleh karena itu, dibutuhkan suatu strategi untuk meningkatkan daya saing  produk rotan di pasar dunia. Strategi ini dapat diperoleh dengan melakukan analisis value chain. Tujuan dari penelitian ini adalah untuk menganalisis rantai nilai produk mebel rotan dan mendapatkan strategi kompetitif yang tepat untuk diterapkan oleh setiap pelaku rantai nilai. Metode yang dilakukan adalah analisis finansial, analisis SWOT, analisis Competitiveness Diamond, dan analisis Critical Success Factor (CSF. Objek penelitian adalah perusahaan-perusahaan yang merupakan anggota dari Asosiasi Pengusaha Mebel Indonesia (ASMINDO Cirebon yang memproduksi mebel rotan single chair. Dari hasil pengolahan data dan analisis diperoleh hasil bahwa strategi yang dapat diterapkan di pihak supplier dalam hal ini pengumpul adalah mendirikan anak perusahaan di tempat tersedia bahan baku dan melakukan merger dengan perusahaan. Strategi yang dapat diterapkan di pihak perusahaan adalah menerapkan upah tenaga kerja per unit produk yang dihasilkan, pengalokasian dana untuk promosi, memprioritaskan buyer langganan, sharing informasi dan inovasi dengan buyer, memiliki fleksibilitas yang tinggi dalam hal kualitas dan harga, bekerjasama dengan asosiasi dan pemerintah dalam kegiatan pameran, dan melakukan merger dengan perusahaan lain ataupun dengan supplier. Sedangkan strategi yang dapat diterapkan di pihak buyer dalam hal ini wholeseller adalah menurunkan harga produk, memaksimalkan promosi dan menjaga hubungan baik dengan perusahaan yang sudah menjadi kepercayaan. Kata Kunci: mebel rotan, value

  19. Building HTML5 games with ImpactJS an introduction on HTML5 game development

    CERN Document Server

    Freeman, Jesse

    2012-01-01

    Create a real 2D game from start to finish with ImpactJS, the JavaScript game framework that works with the HTML5's Canvas element. Making video games is hard work that requires technical skills, a lot of planning, and-most critically-a commitment to completing the project. With this hands-on guide, you'll learn how to use Impact with other technologies step-by-step. You'll pick up important tips about game design, and discover how to publish Impact games to the Web, desktop, and mobile-including a method to package your game as a native iOS app. Packed with screen shots and sample code, this book is ideal for game developers of all levels. Set up your development environment and discover Impact's advantagesBuild a complete game with core logic, collision detection, and player and monster behaviorLearn why a game design document is critical before you start buildingDisplay and animate game artwork with sprite sheetsAdd sound effects, background music, and textCreate screens to display stats and in-game statu...

  20. Crosslinking Protein Glutathionylation Mediated by O2-Arylated Bis-Diazeniumdiolate “Double JS-K”

    Science.gov (United States)

    Holland, Ryan J.; Maciag, Anna E.; Kumar, Varun; Shi, Lei; Saavedra, Joseph E.; Prud’homme, Robert K.; Chakrapani, Harinath; Keefer, Larry K.

    2012-01-01

    Attachment of glutathione (GSH) to cysteine residues in proteins (S-glutathionylation) is a reversible post-translational modification that can profoundly alter protein structure and function. Often serving in a protective role, e.g., by temporarily saving protein thiols from irreversible oxidation and inactivation, glutathionylation can be identified and semi-quantitatively assessed using anti-GSH antibodies, thought to be specific for recognition of the S-glutathionylation modification. Here we describe an alternate mechanism of protein glutathionylation in which the sulfur atoms of the GSH and the protein’s thiol group are covalently bound via a crosslinking agent, rather than through a disulfide bond. This form of thiol crosslinking has been shown to occur and confirmed by mass spectrometry at the solution chemistry level, as well as in experiments documenting the potent antiproliferative activity of the bis-diazeniumdiolate Double JS-K in H1703 cells in vitro and in vivo. The modification is recognized by the anti-GSH antibody as if it were authentic S-glutathionylation, requiring mass spectrometry to distinguish between them. PMID:23106594

  1. Analisis Potensi Ledakan dan Kebakaran Primary Reformer sebagai Unit Proses Produksi Amonia di PT. X

    Directory of Open Access Journals (Sweden)

    Resti Ayu Lestari

    2016-12-01

    Full Text Available Peningkatan industri pupuk di dunia berimplikasi pada peningkatan jumlah industri amonia. Amonia memegang peranan penting pada proses produksi pupuk dalam hal penyediaan nitrogen. Proses pembuatan amonia melibatkan bahan baku berupa gas alam yang bersifat flammable dengan temperatur dan tekanan yang tinggi dalam setiap tahapan prosesnya. Primary reformer merupakan salah satu peralatan proses dalam produksi amonia dengan temperatur dan tekanan paling tinggi serta paling berisiko mengalami kegagalan yang dapat mengakibatkan terjadinya kebakaran/ledakan. Primary reformer berperan sebagai salah satu tahapan pemurnian gas alam dengan hasil berupa karbon monoksida. Identifikasi bahaya pada unit primary reformer dilakukan dengan menggunakan metode Fault Tree Analysis (FTA. Hasil analisis FTA menghasilkan bahwa sumber bahaya dari ledakan primary reformer dapat ditinjau dari faktor teknis dan faktor non teknis. Faktor non teknis menyumbang 74% dari penyebab terjadinya ledakan/kebakaran pada primary reformer. Hasil analisis risiko ledakan/kebakaran pada primary reformer dilakukan dengan menggunakan Dow’s Fire & Explosion Index  dengan hasil radius area dampak adalah 51 meter. Nilai kerugian finansial mencapai US$ 23.640.285 dengan kerugian hari kerja minimal adalah 138 hari. Perangkat lunak Arial Location of Hazardous Atmospheres menghasilkan radius ledakan dengan dampak terkecil yaitu dapat memecahkan kaca jendela/pintu (0,5 psi adalah 73 m dari primary reformer. Radius ledakan dengan kekuatan ledakan 1 psi (meruntuhkan rumah/perkantoran adalah 48 m dari primary reformer.

  2. BAHASA DAN IDEOLOGI: MENGUNGKAP IDEOLOGI DAN KEKUASAAN SIMBOLIK DI BALIK PENGGUNAAN BAHASA (KAJIAN TEKS MEDIA MELALUI ANALISIS WACANA KRITIS

    Directory of Open Access Journals (Sweden)

    Su haryo

    2014-11-01

    Full Text Available Abstrak   Tulisan ini didasari sebuah anggapan bahwa bahasa tidak berada di ruang hampa sosial.Maka, bahasa pada dasarnya bukan hanya untaian kata yang hanya bersifat linguistik, tetapi bersifat sosial. Karenanya, bahasa dipahami sebagai tindakan sosial.Implikasinya, bahasa bukan hanya bermatra linguistik, tetapi juga bermatra sosial. Van Dijk menjadi salah satu model yang dapat digunakan sebagai alat untuk menganalisis wacana secara kritis. Penelitian analisis wacana kritis model van Dijk mempertimbangkan teks, konteks, kognisi sosial, dan analisis/konteks sosial. Untuk mengungkap hal itu, langkah yang dapat dilakukan adalah: mengungkap struktur makro (tematik, suprstruktur (skematik, dan struktur mikro yang terdiri atas semantik, sintaksis, stilitistik, dan retorika. Untuk mengungkap hal itu, di sini digunakan metode simak dan catat dengan menjadikan Suara Merdeka dan Kompassebagai sumber datanya. Hasilnya pertama,SM cenderung berideologi kasar, provokatif, dan konotatif/figuratif. Hal itu, tampak pada pilihan kata/kalimat  kata yang cenderung kasar, seperti mengancam,menyerang, memanggil paksa, menyeret, menembak.Sementara, harian K cenderung berideologi idealisme pers yang objektif, netral, dan berimbang. Kedua, dari dimensi kekuasaan (simbolik, harian SM cenderung menjadi “oposisi”  dan “oposan”sebagai pihak yang di-dominan-kan, sedang pihak pemerintah sebagai pihak yang “dimarginalkan”. Sementara, harian K menempatkan pihak yang dominan/marginal lebih didasarkan pada kondisi objektif di lapangan yang  berbasis data dan keterangan yang dari narasumber yang cenderung netral, seperti pengamat, warga, dan akademisi; tidak didasarkan pada keterangan yang cenderung subjektif, seperti dari para politisi.Ketiga, dari sisi analisis sosial dan kognisi sosial; SM lebih tampak sebagai cerminan tagline-nya yaitu lokal (yaitu “perekat komunitas Jawa Tengah”, sedangkan harian K lebih “mengabdi” pada rakyat seperti tampak pada

  3. ANALISIS MANFAAT BIAYA LINGKUNGAN USAHA TERNAK BABI: STUDI KASUS DI DESA AMBARKETAWANG KECAMATAN GAMPING KABUPATEN SLEMAN (Benefit Cost Analysis of Pig Farming Environment: Case Study at Ambarketawang Village, Gamping District, Sleman Regency, Indonesia

    Directory of Open Access Journals (Sweden)

    Tri Anggraeni Kusumastuti

    2001-12-01

    Full Text Available ABSTRAK Penelitian ini bertujuan untuk mengetahui pendapatan peternak dan kelayakan pengembangan usaha ternak babi secara finansial maupun ekonomi. Penelitian dilakukan di Kecamatan Gamping. Data yang digunakan adalah data primer dari responden peternak dan data sekunder dari instansi terkait. Analisis yang digunakan adalah analisis pendapatan metode R/C Ratio, NPV (Net Present Value, dan IRR (Internal Rate of Return dengan umur ekonomis kandang selama 3 tahun. Hasil penelitian menunjukkan bahwa analisis pendapatan secara finansial menghasilkan nilai lebih tinggi dibandingkan penilaian secara ekonomi. Jenis penggemukan memberikanpendapatan tertinggi secara finansial, sedangkan secaraekonomi, dengan memperhitungkan lingkungan, jenis kombinasi memberikan pendapatan tertinggi. Analisis sensitivitas menunjukkan bahwa penurunan harga babi berpengaruh terhadap penurunan pendapatan peternak dibandingkan peningkatan harga pakan dan peningkatan biaya lingkungan. Jenis pembibitan paling peka terhadap analisis sensitivitas, sedangkan jenis kombinasi penggemukan dan pembibitan tidak begitu terpengaruhi.   ABSTRACT The objectives of this research were to assess the farmer’s income and the feasibility of pig farming, financially as well as economically. The data used in this research were primary data from pig farmers and secondary data from relevant institution. Financial and economic analysis of income and feasibility study with NPV (Net Present Value, B/C ratio, IRR (Internal Rate of Return with economic barn value of 3 years, were applied in this research. The results showed that financially the fattening system gave the highest income, but the combination system was more efficient because it provided the highest income, but the combination system was more efficient because it provided the highest income, inspite of taking into consideration the environment effect. Sensitivity analysis showed that the pig price’s decline influenced the farmer

  4. Statistical analysis of the wind around a nuclear power plant; Analisis estadistico del viento alrededor de una central nucleoelectrica

    Energy Technology Data Exchange (ETDEWEB)

    Tejeda, A; Alvarez, Oscar; Contreras, A D; Jauregui, E [Universidad Veracruzana, (Mexico)

    1997-12-31

    In order to show an appropriate methodology for the climatic analysis of the wind, some of the recent results in the investigation of the field flow around the Laguna Verde Nuclear Power Station, at Veracruz State (Mexico,) through the angular correlation coefficients and contingency tables among the registered wind directions by a meteorological tower at the levels of 10 and 60 meters high are presented. Finally, by applying an objective analysis of the data some conclusions are obtained in connection with the local winds with the mesoscale systems. [Espanol] Con el objeto de mostrar una metodologia apropiada en el analisis climatico del viento, se presentan algunos resultados recientes en la investigacion del campo de flujo en los alrededores de la central nucleoelectrica de Laguna Verde, Veracruz (Mexico), a traves de los coeficientes de correlacion angulares y de tablas de contingencia entre las direcciones del viento registradas por una torre meteorologica en los niveles de 10 y 60 metros de altura. Finalmente, aplicando analisis objetivo de los datos, se obtienen algunas conclusiones sobre la conexion de los vientos locales con los sistemas de mesoescala.

  5. Statistical analysis of the wind around a nuclear power plant; Analisis estadistico del viento alrededor de una central nucleoelectrica

    Energy Technology Data Exchange (ETDEWEB)

    Tejeda, A; Alvarez, Oscar; Contreras, A. D.; Jauregui, E. [Universidad Veracruzana, (Mexico)

    1996-12-31

    In order to show an appropriate methodology for the climatic analysis of the wind, some of the recent results in the investigation of the field flow around the Laguna Verde Nuclear Power Station, at Veracruz State (Mexico,) through the angular correlation coefficients and contingency tables among the registered wind directions by a meteorological tower at the levels of 10 and 60 meters high are presented. Finally, by applying an objective analysis of the data some conclusions are obtained in connection with the local winds with the mesoscale systems. [Espanol] Con el objeto de mostrar una metodologia apropiada en el analisis climatico del viento, se presentan algunos resultados recientes en la investigacion del campo de flujo en los alrededores de la central nucleoelectrica de Laguna Verde, Veracruz (Mexico), a traves de los coeficientes de correlacion angulares y de tablas de contingencia entre las direcciones del viento registradas por una torre meteorologica en los niveles de 10 y 60 metros de altura. Finalmente, aplicando analisis objetivo de los datos, se obtienen algunas conclusiones sobre la conexion de los vientos locales con los sistemas de mesoescala.

  6. An assessment of econometric models applied to fossil fuel power generation; Un'analisi critica dell'applicazione dei modelli econometrici alla generazione termoelettrica

    Energy Technology Data Exchange (ETDEWEB)

    Gracceva, F.; Quercioli, R. [ENEA, Funzione Centrale Studi, Centro Ricerche Casaccia, Rome (Italy)

    2001-07-01

    The main purpose of this report is to provide a general view of those studies, in which the econometric approach is applied to the selection of fuel in fossil fired power generation, focusing the attention to the key role played by the fuel prices. The report consists of a methodological analysis and a survey of the studies available in literature. The methodological analysis allows to assess the adequateness of the econometric approach, in the electrical power utilities policy. With this purpose, the fundamentals of microeconomics, which are the basis of the econometric models, are pointed out and discussed, and then the hypotheses, which are needed to be assumed for complying the economic theory, are verified in their actual implementation in the power generation sector. The survey of the available studies provides a detailed description of the Translog and Logit models, and the results achieved with their application. From these results, the estimated models show to fit the data with good approximation, a certain degree of interfuel substitution and a meaningful reaction to prices on demand side. [Italian] In questo rapporto viene tracciato un quadro generale degli studi che utilizzano modelli econometrici per analizzare la scelta dei combustibili nella termogenerazione, con particoalre attenzione al ruolo svolto dal prezzo dei combustibili. La trattazione si compone di un'analisi di tipo metodologico e di una rassegna della letteratura. L'analisi metodologica consente di valutare l'adeguatezza dell'approccio econometrico nell'analisi del comportamento delle imprese di generazione elettrica. A tal fine vengono esplicitati e discussi i fondamenti microeconomici su cui poggiano i modelli econometrici, e viene verificata la sussistenza, nel settore termoelettrico, delle ipotesi che e' necessario assumere per soddisfare la teoria economica. La rassegna fornisce invece una descrizione dei modelli translog e logit lineare, ed un'analisi

  7. Ambiente sonoro e percezione di alcune caratteristiche dei parchi urbani: analisi e modelli - Sonic environment and perception of some features of urban parks: analysis and models

    Directory of Open Access Journals (Sweden)

    Giovanni Brambilla

    2016-07-01

    Full Text Available Sui dati raccolti in otto parchi urbani, comprendenti alcuni parametri acustici e le valutazioni dei fruitori sulla qualità complessiva del parco percepita e di alcune sue caratteristiche, si è proceduto a diverse analisi statistiche. L’analisi delle componenti principali e quella cluster gerarchica sui dati acustici ha fornito una classificazione in tre gruppi risultata poco sovrapponibile a quella ottenuta con l’analisi cluster e delle corrispondenze multiple condotta sui responsi soggettivi. La discrepanza, confermata anche da alcuni modelli di regressione logistica multinomiale, evidenzia l’influenza di altri fattori non acustici sulla percezione dell’ambiente dei parchi urbani. ------ Different statistical analyses have been carried out on data collected in eight urban parks, including some acoustical parameters and the appraisals of park visitors on the perceived overall quality of the park and some of its features. Principal component analysis and hierarchical cluster one on the acoustic data have identified three groups. This classification poorly overlaps that obtained by hierarchical cluster analysis and multiple correspondence one performed on subjective appraisals data. The difference, confirmed also by models developed by multinomial logistic regression, points out the influence of other non-acoustic factors on the perception of the urban parks environment.

  8. Metabolism and disposition of a novel antineoplastic JS-38 (Benzamide, N-[4-(2,4-dimethoxyphenyl)-4,5-dihydro-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl]-3,5-bis (trifluoromethyl)-(9Cl)) in rats.

    Science.gov (United States)

    Zhang, Hong; Liu, Quanhai; Fan, Tingting; Fang, Yu; Li, Ying; Wang, Guoping

    2012-03-01

    The metabolism and catabolism of a novel antineoplastic (ID code JS-38),Benzamide, N-[4-(2,4-dimethoxyphenyl)-4,5-dihydro-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl]-3,5-bis (trifluoromethyl)-(9Cl), were investigated in Wistar rats (3 female, 3 male). LC/UV, LC/MS, LC/MS/MS, NMR and acid hydrolysis methods showed that the metabolic process of JS-38 consists of a series of acetylation and glucoronation that form a metabolic product with a unique pharmacologic property of accelerating bone-marrow cell formation, and also showed a novel metabolic pathway of being acetylated and glucuronated in series.

  9. Analisis Six Sigma pada Produk Casing Pompa sebagai Metode Perbaikan Kualitas (Studi Kasus: PT. Zenith Allmart Precisindo)

    OpenAIRE

    Haryono, Haryono; Rakasiwi, Hafiedza Pradana

    2014-01-01

    Pada Februari 2014, produk baja terbanyak yang diproduksi PT. Zenith Allmart Precisindo (ZAP) adalah casing pompa dengan reject sebesar 3,35%, padahal target maksimal reject 2% per bulan, ada gap sebesar 1,35%. Analisis DMAIC Six Sigma dilaksanakan untuk mengurangi persentase reject. Pada define, ditentukan project charter, peta proses produksi, dan SIPOC diagram. Dari SIPOC diagram ditentukan 10 CTQ. Pada fase measure dilakukan attribute agreement analysis untuk QC, hasilnya adalah repeabili...

  10. Analisis Niat Penggunaan E-filing Di PT “X” Dan Pt”y” Surabaya Dengan Structural Equation Modeling

    OpenAIRE

    Jimantoro, Christina; Tjondro, Elisa

    2014-01-01

    Penelitian ini dilakukan untuk mengetahui pengaruh persepsi kegunaan, persepsi kemudahan, sikap penggunaan, norma subjektif dan persepsi kemampuan mengontrol terhadap niat penggunaan e-filing oleh wajib pajak orang pribadi. Sampel penelitian ini adalah 64 karyawan PT “X” dan PT “Y” di Surabaya. Teknik analisis data yang digunakan adalah Structural Equation Modelling berbasis Variance (Partial Least Square).Hasil penelitian ini menunjukkan adanya pengaruh persepsi kegunaan dan kemudahan terhad...

  11. ANALISIS PENERAPAN STRATEGI PEMASARAN DALAM PENINGKATAN PANGSA PASAR PADA PT. HADJI KALLA (TOYOTA) CABANG URIP DI MAKASSAR

    OpenAIRE

    MAULADI RAHMAN, EKI

    2012-01-01

    - EKI MAULADI RAHMAN, A211 076 644. Analisis Penerapan Strategi Pemasaran Dalam Peningkatan Pangsa Pasar Pada PT. Hadji Kalla (Toyota) Cabang Urip di Makassar. (dibimbing oleh Muhammad Ismail dan Mukhtar) Tujuan dari penelitian ini adalah untuk mengetahui penerapan strategi pemasaran mobil Toyota pada PT. Hadji Kalla (Toyota) Cabang Urip di Makassar melalui penerapan (produk, harga, promosi dan saluran distribusi) dalam peningkatan pangsa pasar, untuk menganlisis sejauh mana penerapan ...

  12. Optimization of Bacillus aerius strain JS-786 cell dry mass and its antifungal activity against Botrytis cinerea using response surface methodology

    Directory of Open Access Journals (Sweden)

    Shafi Jamil

    2017-01-01

    Full Text Available The optimization of fermentation conditions is necessary for field application of biological control agents. The present study was designed to optimize the fermentation conditions for the Bacillus aerius strain, JS-786 in terms of cell dry mass and its antifungal activity against Botrytis cinerea with response surface methodology. A strain of bacteria with strong antifungal activity was isolated from the phyllosphere of tomato plant and identified as B. aerius JS-786 based on the sequence homology of its 16S rRNA gene. After the success of preliminary antifungal activity tests, response surface methodology was used to optimize the fermentation conditions (medium pH, gelatin percentage, incubation period, rotatory speed and incubation temperature to maximize the cell dry mass and antifungal activity against B. cinerea. A 25 factorial central composite design was employed and multiple response optimization was used to determine the desirability of the operation. The results of regression analysis showed that at the individual level, all of the experimental parameters were significant for cell dry mass; significant results were obtained for antifungal activity pH, incubation period, rotatory speed and incubation temperature. The interactive effect of the incubation period, rotatory speed and incubation temperature was significant. Maximum cell dry mass (8.7 g/L and inhibition zone (30.4 mm were obtained at pH 6.4, gelatin 3.2%, incubation period 36.92 h, rotatory speed 163 rpm, and temperature 33.5°C. This study should help to formulate a more rational and cost-effective biological product both in terms of bacterial growth and antifungal activity.

  13. Analisi dell’anisotropia microstrutturale in materiali compositi rinforzati con fibre corte

    Directory of Open Access Journals (Sweden)

    D. Dreossi

    2008-01-01

    Full Text Available La microtomografia con luce di sincrotrone si è rivelata una tecnica particolarmente efficace per l’analisi della struttura risultante dalla distribuzione degli orientamenti assunti dalle fibre di rinforzo di compositi rinforzati con fibre di vetro. La ricostruzione dell'immagine tridimensionale ha consentito la visualizzazionedella distribuzione spaziale delle fibre all'interno della matrice polimerica anche nel caso di fibre di piccole dimensioni (diametro medio di 10 micrometri. E' stato quindi possibile misurare le differenze nell'orientamento delle fibre nei differenti strati di un campione utilizzando metodi basati sulla valutazione del Mean Intercept Length (MIL e del fabric tensor. La tecnica descritta è stata applicata a un campione di poliammide 6 rinforzato con il 30% di fibre corte di vetro ricavato da lastra.

  14. Detection of irradiated spice in blend of irradiated and un-irradiated spices using thermoluminescence method

    International Nuclear Information System (INIS)

    Goto, Michiko; Yamazaki, Masao; Sekiguchi, Masayuki; Todoriki, Setsuko; Miyahara, Makoto

    2007-01-01

    Five blended spice sample were prepared by mixing irradiated and un-irradiated black pepper and paprika at different ratios. Blended black pepper containing 2%(w/w) of 5.4 kGy-irradiated black pepper showed no maximum at glow1. Irradiated black pepper samples, mixed to 5 or 10%(w/w), were identified as 'irradiated' or 'partially irradiated' or 'un-irradiated'. All samples with un-irradiated pepper up to 20%(w/w) were identified as irradiated'. In the case 5.0 kGy-irradiated paprika were mixed with un-irradiated paprika up to 5%(w/w), all samples were identified as irradiated'. The glow1 curves of samples, including irradiated paprika at 0.2%(w/w) or higher, exhibited a maximum between 150 and 250degC. The results suggest the existence of different critical mixing ratio for the detection of irradiation among each spices. Temperature range for integration of the TL glow intensity were compared between 70-400degC and approximate 150-250degC, and revealed that the latter temperature range was determined based on the measurement of TLD100. Although TL glow ratio in 150-250degC was lower than that of 70-400degC range, identification of irradiation was not affected. Treatment of un-irradiated black pepper and paprika with ultraviolet rays had no effect on the detection of irradiation. (author)

  15. Absolute Magnetization Distribution on Back-arc Spreading Axis Hosting Hydrothermal Vents; Insight from Shinkai 6500 Magnetic Survey

    Science.gov (United States)

    Fujii, M.; Okino, K.; Honsho, C.; Mochizuki, N.; Szitkar, F.; Dyment, J.

    2013-12-01

    Near-bottom magnetic profiling using submersible, deep-tow, Remotely Operated Vehicle (ROV) and Autonomous Underwater Vehicle (AUV) make possible to conduct high-resolution surveys and depict detailed magnetic features reflecting, for instance, the presence of fresh lavas or hydrothermal alteration, or geomagnetic paleo-intensity variations. We conducted near-bottom three component magnetic measurements onboard submersible Shinkai 6500 in the Southern Mariana Trough, where five active hydrothermal vent fields (Snail, Yamanaka, Archean, Pica, and Urashima sites) have been found in both on- and off-axis areas of the active back-arc spreading center, to detect signals from hydrothermally altered rock and to distinguish old and new submarine lava flows. Fourteen dives were carried out at an altitude of 1-40 m during the R/V Yokosuka YK10-10 and YK10-11 cruises in 2010. We carefully corrected the effect of the induced and permanent magnetizations of the submersible by applying the correction method for the shipboard three-component magnetometer measurement modified for deep-sea measurement, and subtracted the IGRF values from the corrected data to obtain geomagnetic vector anomalies along the dive tracks. We then calculated the synthetic magnetic vector field produced by seafloor, assumed to be uniformly magnetized, using three dimensional forward modeling. Finally, values of the absolute magnetizations were estimated by using a linear transfer function in the Fourier domain from the observed and synthetic magnetic anomalies. The distribution of estimated absolute magnetization generally shows low values around the five hydrothermal vent sites. This result is consistent with the equivalent magnetization distribution obtained from previous AUV survey data. The areas of low magnetization are also consistent with hydrothermal deposits identified in video records. These results suggest that low magnetic signals are due to hydrothermal alteration zones where host rocks are

  16. Correlacion entre metodos de analisis de Zn disponible en cuatro ordenes de suelos de Costa Rica

    OpenAIRE

    Eloy Molina; Elemer Bornemisza

    2001-01-01

    Se realizo una comparación entre métodos analisis del Zn disponible en 4 ordenes de sue- Analytilos de Costa Rica (Ultisoles, Vertisoles, Andisoles Inceptisoles, 25 de c/u), utilizando las siguientes soluciones extractoras: Olsen Modificado, Meh- lich 3, Morgan Modificado, DTPA y HC1. Las cantidades de Zn extrafdas dependieron de la natu- raleza qufmica de la solucion extractora. El HCl presento los contenidos mas altos de Zn en los chasuelos, excepto en Vertisoles....

  17. ANALISIS DEKONSTRUKSI TOKOH TAKESHI DAN MITSUSABURO DALAM NOVEL SILENT CRY KARYA KENZABURO OE PERSPEKTIF JACQUES DERRIDA

    Directory of Open Access Journals (Sweden)

    Abd. Ghofur

    2015-12-01

    Full Text Available This article is a little result done by the writer, in which critical analisys discourse study as a tool to learn literature. It is Kenzaburo Oe’s writing, a Japan writer who got Pulitzer or noble in literature. It employs Jaques Derrida deconstructive theory, while the researcher focuses on binary opposition.  When deconstruction used, it will expose inside of the text, furthermore it produces other meaning or different point of view from the real text.

  18. ANALISIS STRUKTUR MIKRO LAPISAN BOND COAT NIAL THERMAL BARRIER COATING (TBC PADA PADUAN LOGAM BERBASIS CO

    Directory of Open Access Journals (Sweden)

    Toto Sudiro

    2012-11-01

    Full Text Available Kehandalan dan umur pakai sistem Thermal Barrier Coating (TBC ditentukan oleh kestabilan lapisan bond coat dan thermal grown oxide (TGO. Sehingga sangatlah penting untuk memahami mekanisme pembentukan dan degradasi lapisan ini. Pada makalah ini akan dibahas analisis struktur mikro lapisan bond coat NiAl yang dideposisikan pada substrat CoCrNi dengan menggunakan gabungan metoda electroplating dan pack-cementation. Pada makalah ini juga dibahas mekanisme pembentukan void disepanjang interface bond coat¬-substrat setelah tes oksidasi.

  19. KLASIFIKASI INTI SEL PAP SMEAR BERDASARKAN ANALISIS TEKSTUR MENGGUNAKAN CORRELATION-BASED FEATURE SELECTION BERBASIS ALGORITMA C4.5

    Directory of Open Access Journals (Sweden)

    Toni Arifin

    2014-09-01

    Full Text Available Abstract - Pap Smear is an early examination to diagnose whether there’s indication cervical cancer or not, the process of observations were done by observing pap smear cell under the microscope. There’s so many research has been done to differentiate between normal and abnormal cell. In this research presents a classification of pap smear cell based on texture analysis. This research is using the Harlev image which amounts to 280 images, 140 images are used as training data and 140 images other are used as testing. On the texture analysis used Gray level Co-occurance Matrix (GLCM method with 5 parameters that is correlation, energy, homogeneity and entropy added by counting the value of brightness. For choose which the best attribute used correlation-based feature selection method and than used C45 algorithm for produce classification rule. The result accuracy of the classification normal and abnormal used decision tree C45 is 96,43% and errors in predicting is 3,57%. Keywords : Classification, Pap Smear cell image, texture analysis, Correlation-based feature selection, C45 algorithm. Abstrak - Pap Smear merupakan pemeriksaan dini untuk mendiagnosa apakah ada indikasi kanker serviks atau tidak, proses pengamatan dilakukan dengan mengamati sel pap smear dibawah mikroskop. Banyak penelitian yang telah dilakukan untuk membedakan antara sel normal dan abnormal. Dalam penelitian ini menyajikan klasifikasi inti sel pap smear berdasarkan analisis tektur. Citra yang digunakan dalam penelitian ini adalah citra Harlev yang berjumlah 280 citra, 140 citra digunakan sebagai data training dan 140 citra lain digunakan sebagai testing. Pada analisis tekstur mengunakan metode Gray level Co-occurrence Matrix (GLCM menggunakan 5 parameter yaitu korelasi, energi, homogenitas dan entropi ditambah dengan menghitung nilai brightness. Untuk memilih mana atribut terbaik digunakan metode correlation-based feature selection lalu digunakan algoritma C45 untuk

  20. Analisis Implementasi Akuntansi Berbasis Akrual pada Inspektorat Jenderal Kementerian Keuangan

    Directory of Open Access Journals (Sweden)

    Eliada Herwiyanti

    2017-05-01

    Full Text Available Penelitian ini merupakan penelitian kualitatif terhadap penerapan Sistem Akuntansi Pemerintahan berbasis akrual di lingkungan Inspektorat Jenderal Kementerian Keuangan. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana kesiapan dan penerapan SAP Berbasis Akrual di instansi tersebut. Data dalam penelitian ini dikumpulkan melalui observasi, studi kepustakaan, serta wawancara terhadap sepuluh orang informan yang terkait langsung dengan penerapan SAP berbasis akrual. Data yang telah dikumpulkan kemudian dianalisis dan diinterpretasikan secara naratif dengan menggunakan metode analisis data kualitatif yang direkomendasikan oleh Creswell (2012. Hasil penelitian ini menunjukkan bahwa secara umum, kesiapan Itjen Kemenkeu dalam menerapkan sistem akuntansi akrual sudah baik, mulai dari aspek komunikasi, sumber daya, komitmen organisasi, dan struktur birokrasi. Dengan kesiapan yang baik, penelitian ini juga menun­juk­kan bahwa penerapan sistem akuntansi akrual di Itjen Kemenkeu sudah dilakukan dengan sangat memuaskan, yang ditunjukkan dengan nilai sebesar 93,40%.

  1. ANALISIS LEMBAR KERJA SISWA DALAM MENINGKATKAN KOMUNIKASI MATEMATIS TULIS SISWA

    Directory of Open Access Journals (Sweden)

    Fimmatur Rizka Ardina

    2016-02-01

    Komunikasi merupakan suatu kemampuan yang penting untuk dimiliki setiap manusia. Komunikasi dalam artikel ini difokuskan pada komunikasi matematis tulis. Komunikasi matematis tulis ini akan berhubungan dengan lembar kerja siswa yang dipakai dalam proses pembelajaran. Tujuan penulisan artikel ini adalah untuk mendeskripsikan proses analisis LKS sebagai alat untuk meningkatkan komunikasi matematis tulis siswa. Jenis penelitian yang digunakan adalah kualitatif deskriptif. LKS akan dianalisis menggunakan standar indikator kemampuan komunikasi NCTM (2000 yang dimodifikasi sehingga terdapat empat indikator yaitu (1 siswa dapat menuliskan ide yang dimiliki dengan jelas dan tepat (2 siswa dapat menuliskan alasan untuk jawaban yang diberikan (3 siswa dapat memberikan tanggapan untuk ide atau jawaban siswa lain (4 siswa dapat menuliskan kembali ide orang lain menggunakan bahasanya sendiri. Berdasarkan hasil penelitian dapat disimpulkan bahwa LKS oleh Tim MGMP Kota Malang tidak dapat digunakan sebagai alternatif untuk meningkatkan kemmapuan komunikasi matematis tulis siswa.

  2. Effect of infliximab on the levels of TNF-α and TGF-β in the whole blood cultures of irradiated patients

    International Nuclear Information System (INIS)

    Staroslawska, E.; Czarnocki, K. J.; Koziol-Montewka, M.; Donica, H.; Magrys, A.

    2008-01-01

    TGF-β is supposed to be the major cytokine responsible for post-radiation fibrosis of healthy tissues and actively modifies post-radiation changes. The growth of TGF-β level induces the expression of collagen synthesis gene which triggers off the production of fibrosis of hyaline membranes. The main purpose of this study was to discover the way and methods of reducing post-radiation damage of normal tissues and provide an adequate scientific justification for using Infliximab as an effective radio protector in the neoplasm radiotherapy. A group of 97 patients were subjected to the experiment. Randomly selected patients were assigned to 3 groups according to the radiation exposure. The samples of whole blood were suspended in RPMI 1640 growth medium standardized according to the number of leukocytes. Two milliliters of whole blood was taken from each patient immediately before irradiation and 100 microliter sample of the blood was placed in wells with 0.8 mg/ml of Infliximab or without the preparation. TGF-β levels in blood culture without cA2 before irradiation showed continuous rise from 3978 to 8950 pg/ml at the 96th h. In the post irradiated group without cA2, a continuous growth was recorded till the 48th h (from 4758 to 13324 pg/ml at the 24th h) and then a slight decline to 11950 pg/ml at 96th h, respectively. In the cultures with cA2, TGF-β levels before irradiation showed also the peak value at the 48th h (from 4050 to 7340 pg/ml at the 48th h) and then started to go down (6500 pg/ml at the 72nd h and 5720 pg/ml at the 96th h). In the post-irradiated group, during the first 6 hours, there was a growth from 4717 pg/ml to 7462 pg/ml, and then a paradoxical increase to 16885 pg/ml at the 12th h. From the 12th h the values started to decrease to 6895 pg/ml at the 96th h. The obtained results confirmed the hypothesis of decreasing the TGF-β expression by inactivating TNF-α with a monoclonal antibody (Infliximab) in the patients whole blood culture in vitro

  3. PENGEMBANGAN MODEL PREDIKSI MADDEN-JULIAN OSCILLATION (MJO BERBASIS HASIL ANALISIS DATA WIND PROFILER RADAR (WPR

    Directory of Open Access Journals (Sweden)

    Naziah Madani

    2014-07-01

    Full Text Available Latar belakang penelitian ini adalah pentingnya kajian mengenai MJO sebagai salah satu osilasi dominan di kawasan ekuator. Penelitian ini bertujuan untuk membuat model prediksi MJO berdasarkan analisis data WPR. Pada penelitian ini kejadian MJO diidentifikasi dari data kecepatan angin zonal pada lapisan 850 mb di kawasan Pontianak, Manado, dan Biak. Sebelum data angin zonal ini dimanfaatkan untuk melihat perilaku MJO, maka data angin tersebut  terlebih dahulu dibandingkan dengan data indeks MJO yaitu RMM1 dan RMM2. RMM1 dan RMM2 merupakan sepasang indeks untuk memonitor kejadian MJO secara realtime. Hasil analisis Power Spectral Density (PSD data kecepatan angin zonal lapisan 850 mb menunjukkan adanya sinyal MJO kuat yang dicirikan dengan adanya osilasi sekitar 45 harian. Hasil korelasi dan regresi juga menunjukkan bahwa terdapat keterkaitan yang signifikan antara kedua data tersebut. Hal tersebut mengindikasikan bahwa data kecepatan angin zonal lapisan 850 mb dapat digunakan untuk analisis MJO. Pada penelitian ini, prediksi MJO didasarkan pada data kecepatan angin zonal menggunakan metode ARIMA Box-Jenkins. Melalui metode ini, model yang mendekati data deret waktu kecepatan angin zonal pada lapisan 850 mb di Pontianak adalah ARIMA(2,0,0, model prediksi untuk Manado adalah ARIMA(2,1,2, sedangkan untuk Biak adalah ARIMA(0,1,3. Model-model tersebut bermanfaat untuk melihat perilaku sinyal MJO pada data angin zonal berkaitan dengan pola curah hujan di wilayah kajian.   Background of this research is to study the importance of MJO as one of the predominant peak oscillation in the equator area. This study aims to make prediction models of MJO based on the analysis of zonal wind speed data observed by WPR that compared by the MJO index data, namely RMM1 and RMM2. The results of PSD show strong MJO signal of 45 day periods oscillations. The result of corrrelation and regression analyses also show significant relationship between both data. Therefore

  4. ANALISIS TINGKAT KEPUASAN PELANGGAN TERHADAP MUTU LAYANAN ANTAR (DELIVERY SERVICE) DI RESTORAN KFC CABANG AHMAD YANI MAKASSAR

    OpenAIRE

    AMRENY, FANY FEBRIANY

    2012-01-01

    Fany Febriany Amreny (I 311 07 053). Analisis Tingkat Kepuasan Pelanggan terhadap Mutu Layanan Antar di Restoran KFC Cabang Ahmad Yani Makassar. Dibawah Bimbingan Ir. Sofyan nurdin Kasim, M.S sebagai Pembimbing Utama dan Ir. Veronica Sri Lestari, M.Ec sebagai Pembimbing Anggota. Perkembangan dan peningkatan jasa pelayanan pada restoran fast food dari tahun ke tahun semakin menjadi perhatian masyarakat yang dapat dilihat dari ketatnya persaingan yang menyebabkan suatu restoran perlu melaku...

  5. Valutazione dell'appropriatezza dei ricoveri in un Policlinico Universitario: analisi mediante l'uso comparativo dei sistemi di classificazione isogravitá APR-DRG e Disease Staging e del PRUO

    Directory of Open Access Journals (Sweden)

    M. Volpe

    2003-05-01

    Full Text Available

    Obiettivi: valutare l’appropriatezza organizzativa dei ricoveri effettuati in un Policlinico Universitario attraverso la comparazione di due metodi, dei quali uno basato sui dati della scheda di dimissione ospedaliera ed utilizza, rispettivamente, i sistemi di classificazione iso-gravità APR-DRG e Disease Staging e l’altro sulla revisione delle cartelle cliniche mediante il PRUO.

    Metodi: oggetto di analisi sono i ricoveri ordinari effettuati nell’anno 2001 ed afferenti ai DRG inclusi nella delibera della Giunta Regionale del Lazio 864/2002 che recepisce il D.P.C.M. 29/11/2001 sui livelli essenziali di assistenza.

    Risultati: i risultati evidenziano che le due varianti del
    metodo basato sulla SDO (metodo APPRO mostrano quote di ricoveri inappropriati sovrapponibili rispetto al complesso dei ricoveri oggetto di analisi, ma con differenze anche rilevanti tra APR-DRG e Disease Staging in relazione ai singoli DRG considerati, riconducibili ai diversi algoritmi di attribuzione del livello di severità utilizzati dai due sistemi. L’analisi campionaria effettuata con il metodo PRUO su casi afferenti ai DRG della DGR 864/2002 caratterizzati da livelli di severità minimi evidenzia una proporzione di ricoveri inappropriati superiore a quella determinata tramite i metodi basati sulla SDO. Tale differenza è verosimilmente dovuta al ruolo del valore delle soglie percentuali di accettabilità individuate dalla Regione Lazio per ciascun DRG: le quote di ricoveri che eccedono tali soglie sono considerate inappropriate.

    Conclusioni: sulla base dei risultati ottenuti gli autori
    descrivono gli interventi organizzativi adottati per ottimizzare il contesto di erogazione delle prestazioni
    oggetto di analisi, discutono vantaggi e limiti dei metodi SDO-based e del metodo analitico PRUObased e ne propongono l

  6. ANALISIS KEBIJAKAN LINKAGE PROGRAM LEMBAGA KEUANGAN SYARIAH DALAM RANGKA PEMBERDAYAAN UKM DI INDONESIA

    Directory of Open Access Journals (Sweden)

    Siti Hamidah

    2016-03-01

    Linkage program adalah program yang menghubungkan bank dengan pelaku usaha mikro kecil melalui lembaga keuangan mikro. Kelemahan dalam Linkage program adalah pada aspek peraturan yang tersebar dalam berbagai aturan, dan khusus bagi lembaga keuangan syariah terdapat pula kendala berkaitan dengan kesesuaian dengan ketentuan syariah. Dari penelitian dengan pendekatan perundang-undangan dan pendekatan konseptual ini diperoleh inventarisasi serta analisis kebijakan Linkage Program bagi Lembaga Keuangan Syariah dalam hukum positif Indonesia. Kebijakan terkait Linkage program, diklasifikasi dalam 2 kelompok, yaitu kebijakan substansi dan prosedural. Aturan inilah yang menjadi rujukan bagi lembaga keuangan syariah rangka pemberdayaan usaha kecil mikro di Indonesia. Kata kunci: Linkage program, lembaga keuangan syariah, usaha mikro kecil

  7. MAGI: a Node.js web service for fast microRNA-Seq analysis in a GPU infrastructure.

    Science.gov (United States)

    Kim, Jihoon; Levy, Eric; Ferbrache, Alex; Stepanowsky, Petra; Farcas, Claudiu; Wang, Shuang; Brunner, Stefan; Bath, Tyler; Wu, Yuan; Ohno-Machado, Lucila

    2014-10-01

    MAGI is a web service for fast MicroRNA-Seq data analysis in a graphics processing unit (GPU) infrastructure. Using just a browser, users have access to results as web reports in just a few hours->600% end-to-end performance improvement over state of the art. MAGI's salient features are (i) transfer of large input files in native FASTA with Qualities (FASTQ) format through drag-and-drop operations, (ii) rapid prediction of microRNA target genes leveraging parallel computing with GPU devices, (iii) all-in-one analytics with novel feature extraction, statistical test for differential expression and diagnostic plot generation for quality control and (iv) interactive visualization and exploration of results in web reports that are readily available for publication. MAGI relies on the Node.js JavaScript framework, along with NVIDIA CUDA C, PHP: Hypertext Preprocessor (PHP), Perl and R. It is freely available at http://magi.ucsd.edu. © The Author 2014. Published by Oxford University Press.

  8. ANALISIS PERUBAHAN KURIKULUM PADA PROSES PEMBELAJARAN PENDIDIKAN JASMANI OLAHRAGA DAN KESEHATAN DI SEKOLAH DASAR

    Directory of Open Access Journals (Sweden)

    Slamet Yulianto

    2017-01-01

    Tujuan penelitian ini adalah untuk mengetahui perubahan proses pembelajaran PJOK yang dilakukan guru seiring dengan tuntutan perubahan kurikulum sebagai kompetensi keprofesionalan guru. Penelitian ini menggunakan pendekatan penelitian kualitatif dengan jenis fenomenologi untuk menggali data alamiah dari subjek guru PJOK. Pengumpulan data dilakukan oleh peneliti sebagai instrumen kunci dengan teknik wawancara, observasi, dan analisis dokumen kepada subjek guru PJOK di SD inti kota Malang. Hasil penelitian menunjukkan bahwa, guru PJOK telah memenuhi standar profesi guru, guru PJOK telah memahami konsep perubahan kurikulum dan konsep PJOK, namun proses pembelajaran PJOK tidak maksimal sesuai dengan tuntutan perubahan kurikulum sebagai kompetensi keprofesionalan guru.

  9. Analisis Kadar Kofein Kopi Luwak Dengan Variasi Jenis Kopi, Spesies Luwak Dan Cara Pengolahan Dengan Metoda TlC Scanner

    Directory of Open Access Journals (Sweden)

    Rahma Yulia

    2016-07-01

    Full Text Available Telah dilakukan penelitian analisis kadar kofein kopi luwak dengan variasi jenis kopi, spesies luwak dan cara pengolahan dengan metoda TLC Scanner. Analisis dilakukan dengan menggunakan 8 sampel kopi luwak R.Ab.K ; R.Ab.B ; R.Ph.K ; R.Ph.B ; A.Ab.K ; A.Ab.B ; A.Ph.K ; A.Ph.B yang diekstraksi dengan pelarut diklorometana ( DCM . Pemisahan dengan KLT dilakukan dengan fasa diam plat silika gel GF254 dan fasa gerak campuran diklorometana : metanol ( 9,5 : 0,5 . Kadar kofein dihitung dengan menggunakan persamaan regresi y = 2715,112 + 4,389x dan memberikan persentase kadar berturut-turut 1,91 ; 2,04 ; 1,30 ; 1,89 ; 1,29 ; 1,45 ; 1,25 ; 1,42 %. Kadar kofein paling tinggi diberikan oleh kopi robusta yang diberikan pada luwak A. binturong dan diolah secara basah dengan persentase 2,04 %. Sedangkan kadar kofein paling rendah diberikan oleh kopi arabika yang diberikan pada luwak P. hermophroditus dengan persentase 1,25 %. Pengolahan data dengan statistik anova tiga jalan SPSS 21 menunjukkan hasil bahwa jenis kopi, variasi luwak dan cara pengolahan memberikan pengaruh yang signifikan terhadap kadar kofein dengan p < 0,05.

  10. ANALISIS PEMANFAATAN JEJARING SOSIAL UNTUK PENENTUAN KONSENTRASI MAHASISWA DENGAN METODE SOCIAL NETWORK ANALYSIS (Studi Kasus: Universitas Nusantara PGRI Kediri

    Directory of Open Access Journals (Sweden)

    Risky Aswi R

    2015-08-01

    Full Text Available Analisis pemanfaatan  jejaring  sosial untuk penentuan konsentrasi mahasiswa dengan metode sosial network analysis. Tujuan dibangun sistem ini untuk menentukan konsentrasi mahasiswa dengan pendekatan Sosial Network Analisis Studi Kasus Jejaring Sosial Facebook dan mampu memanfaatkan facebook sebagai alat untuk menentukan konsentrasi mahasiswa jurusan teknik informatika menjadi tiga bagian yaitu pemrograman, jaringan, dan multimedia. Batasan yang digunakan dalam penelitian ini adalah penelitian ini hanya berlaku pada mahasiswa yang memiliki akun facebook. Penelitian ini menggunakan Social Network Analysis untuk mencari between centrality.Pada tahap pertama setiap akun akan dilihat relasinya setelah itu hubungan antar akun akan dimasukan ke node XL dan akan menghasilkan between centrality. Mahasiswa yang melanjutkan proses selanjutnya adalah mahasiswa yang nilai betweent centralitynya 85% teratas. Setelah itu akan ditambahkan variabel group yang digunakan untuk mengkelompokan peminatan, dan ditambahkan variabel nilai akademis untuk menguatkan pendapat yang diperoleh sebelumnya.Dengan cara melihat between centrality dan menambahkan variabel group untuk membagi siswa sesuai konsentrasi, dan memabahkan variabel nilai akademik untuk memperkuat pendapat. Sosial network analysis terbukti dapat menentukan konsentrasi mahaiswa. Facebook dapat digunakan sebagai alat untuk menentukan konsentrasi mahasiswa, konsentrasi mahasiswa dibagi menjadi pemrograman, jaringan, dan multimedia. Kata Kunci : Jejaring Sosial, Social Network Analysis, between centrality

  11. Use of radioisotopes in the systematic analysis of impurities in metals of very high purity; Application des radioisotopes a l'analyse systematique des impuretes dans les metaux de tres haute purete; Primenenie radioizotopov v sistematicheskom analize primesej v vysokochistykh metallakh; Aplicacion de los radioelementos al analisis sistematico de las impurezas en los metales muy puros

    Energy Technology Data Exchange (ETDEWEB)

    Albert, Philippe; Gaittet, Jean [Centre d' Etudes de Chimie Metallurgique (C.N.R.S.), Vitry (France)

    1962-01-15

    analytiques. La plupart des radioisotopes sont ensuite isoles radiochimiquement purs et leur identification est obtenue simultanement par l'etude de la periode de decroissance de leur radioactivite et du spectre de leur rayonnement {gamma}. En completant cette analyse systematique, par dosage de certains elements surprise separee, on peut toutefois escompter doser par la methode d'activation une soixantaine d'elements, soit en irradiant dans les neutrons (cas du soufre, phosphore, chlore, baryum), soit en faisant appel aux reactions produites par les deutons (cas du carbone et du bore). Les auteurs insistent tout particulierement sur les resultats et les consequences de leurs analyses. (author) [Spanish] El metodo de la ''fusion por zonas'' permite obtener metales de pureza muy elevada en los que las concentraciones de impurezas son del orden de 10{sup -6} a 10{sup -8}. Estos metales se preparan en pequenas cantidades y, por lo tanto, es de suma importancia poder valorar con gran sensibilidad un numero muy elevado de elementos en una misma muestra. El analisis sistematico del aluminio y del hierro por irradiacion neutronica permite determinar 45 elementos en una muestra de un gramo aproximadamente. Este analisis de un gran numero de impurezas solo pudo realizarse separando en cascada, en mas de 40 fracciones analiticas, los radioisotopos formados durante la irradiacion. Seguidamente, la mayor parte de los radioisotopos se aislan al estado radioquimicamente puro y se identifican por estudio de su periodo de semidesintegracion y del espectro de las radiaciones que emiten. Al complementar este analisis sistematico por la valoracion de ciertos elementos en muestras separadas, el metodo de activacion permitira determinar alrededor de 60 elementos, bien irradiando con neutrones (como en los casos del azufre, fosforo, cloro, bario, etc.), bien recurriendo a las reacciones producidas por los deuterones (casos del carbono y del boro). En el curso de su disertacion, los autores

  12. ANALISIS PENGARUH VARIABILITAS TANAH PADA VARIABILITAS SPEKTRUM RESPON GEMPABUMI

    Directory of Open Access Journals (Sweden)

    I Nyoman Sukanta

    2010-11-01

    Full Text Available Salah satu komplek perkantoran yang terletak di Jalan Thamrin, Jakarta, dipilih sebagai lokasi penelitian. Hasil pemodelan data tanah, menghasilkan 3 lapisan tanah yang berbeda dengan kriteria jenis tanahnya cenderung lunak, dengan nilai N-SPT rata–rata = 11,23. Perhitungan percepatan puncak muka tanah (PGA dan nilai spektrum respon di permukaan tanah menggunakan metoda analisis linier equivalen dengan simulasi Monte Carlo. Program aplikasi SHAKE2000 merupakan alat bantu dalam simulasi, dengan memasukkan beberapa asumsi sebagai data masukan. Data masukan dinamik menggunakan sumber gempabumi Elcentro dan Mexico yang mempunyai kandungan frekuensi berbeda. Asumsi nilai percepatan puncak batuan dasar (PBA untuk kedua sumber gempabumi tersebut sebesar 0,18 g. Hasil analisis menunjukkan nilai spektrum respon dan percepatan puncak muka tanah sangat bervariasi. Gempabumi Elcentro menghasilkan nilai rata–rata PGA = 0,36 g dengan spektrum responnya = 1,0 g  pada Tc = 0,6 detik. Untuk gempabumi Mexico menghasilkan nilai rata–rata PGA = 0,30 g dengan spektrum responnya = 0,9 g pada Tc = 0,6 detik. Artinya, variabilitas jenis tanah sangat berpengaruh tehadap variabilitas spektrum respon di permukaan tanah.   One of the office complex located at Jalan Thamrin, Jakarta, was chosen as the location of the reseach. Results of data modeling soil, produces 3 different soil layers with soil type criteria tend to be soft, with a value of N-SPT  average = 11.23. Calculation of peak ground acceleration (PGA and the value of the response spectrum at ground surface using the method of equivalent linear analysis with Monte Carlo simulation. SHAKE2000 application software  is a tool in the simulation, by including some assumptions as input data. Dynamic input data using Elcentro and Mexican  earthquakes  which have different frequency contents. Assumed value of peak base acceleration (PBA for the two earthquakes was 0.18 g. The result of analysis was the value

  13. LA COMUNICAZIONE POLITICA SUI SOCIAL NETWORK: UN’ANALISI LINGUISTICA

    Directory of Open Access Journals (Sweden)

    Daniele Spoladore

    2014-07-01

    Full Text Available Questo lavoro si propone di analizzare le scelte linguistiche dei soggetti politici che utilizzano Facebook e Twitter per rivolgersi al sempre più frammentato panorama dei potenziali elettori. In particolare, analizza le tendenze linguistiche comuni che questi social network hanno fatto emergere nel rapporto tra politica, web e lettori. Cominciando dall’analisi della presenza di parlamentari e senatori su Facebook e Twitter, si cerca di riassumere le principali caratteristiche delle due piattaforme, per giungere ad una classificazione dei testi prodotti attraverso di esse; si analizza la scrittura di post e tweet, sottolineando la presenza di espedienti tipici del mezzo e valutando il loro effetto sui lettori, e si studiano le scelte sintattiche e morfosintattiche in relazione alla struttura e alle possibilità dei due social network. In ultima analisi si osservano le scelte lessicali dei soggetti politici, studiandone i campi semantici e la quantità di tecnicismi. Infine, si cerca di compiere una valutazione delle due differenti tipologie di trasmesso scritto rinvenute nei campioni, osservando come ognuna di esse abbia uno scopo ben preciso nell’economia della comunicazione politica sui social network. Political communication policy in social networks: a language analysis  Daniele Spoladore This paper aims to analyze the linguistic choices of politicians who use Facebook and Twitter to address the increasingly fragmented landscape of potential voters. In particular, it analyzes the common language trends that these social networks have revealed in the relationship between politics, the web and readers. Starting from the analysis of the presence of MPs and senators on Facebook and Twitter, we try to summarize the key features of the two platforms, in order to arrive at a classification of the texts produced using them.  We analyzed posts and tweets, emphasizing the  typical characteristics of these means and evaluating their effect on

  14. Radioactivity

    International Nuclear Information System (INIS)

    2002-01-01

    This pedagogical document presents the origin, effects and uses of radioactivity: where does radioactivity comes from, effects on the body, measurement, protection against radiations, uses in the medical field, in the electric power industry, in the food (ionization, radio-mutagenesis, irradiations) and other industries (radiography, gauges, detectors, irradiations, tracers), and in research activities (dating, preservation of cultural objects). The document ends with some examples of irradiation levels (examples of natural radioactivity, distribution of the various sources of exposure in France). (J.S.)

  15. Radioactivity; La radioactivite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    This pedagogical document presents the origin, effects and uses of radioactivity: where does radioactivity comes from, effects on the body, measurement, protection against radiations, uses in the medical field, in the electric power industry, in the food (ionization, radio-mutagenesis, irradiations) and other industries (radiography, gauges, detectors, irradiations, tracers), and in research activities (dating, preservation of cultural objects). The document ends with some examples of irradiation levels (examples of natural radioactivity, distribution of the various sources of exposure in France). (J.S.)

  16. Introduzione all'analisi qualitativa dei sistemi dinamici discreti e continui

    CERN Document Server

    Squassina, Marco

    2016-01-01

    Il testo è stato concepito per la struttura degli attuali corsi di laurea in Biologia, Matematica, Matematica Applicata, Ingegneria, Scienze Naturali e Mediche. Esso si concentra sugli aspetti qualitativi delle equazioni differenziali come limitatezza o illimitatezza delle soluzioni, esistenza o non esistenza di orbite periodiche, stabilità o instabilità dei punti di equilibrio, biforcazione del sistema al variare di un parametro, robustezza del sistema in presenza di perturbazioni. L'analisi qualitativa di sistemi dinamici discreti e continui è un argomento tecnicamente accessibile anche agli studenti di primo livello e consente di collegare, combinare ed esercitare nozioni che provengono dall'algebra, dal calcolo differenziale di base e dalla geometria elementare, stimolando l'intuizione matematica. Il volume si caratterizza per due aspetti: quello induttivo e quello figurativo. L'approccio induttivo si basa su un'ampia gamma di problemi risolti e pensati per introdurre, gradualmente, sia le conoscenze ...

  17. Analisis Kenyamanan Serta Redesain Pegas Suspensi Mobil Toyota Fortuner 4.0 V6 SR (AT 4x4

    Directory of Open Access Journals (Sweden)

    Puja Priyambada

    2017-01-01

    Full Text Available Perkembangan dunia otomotif mengalami kemajuan yang sangat pesat. Seiring dengan perkembangan  tersebut kualitas kenyamanan kendaraan merupakan faktor yang harus diperhatikan. Dalam upaya meningkatkan kualitas kenyamanan kendaraan dilakukan pengembangan dalam sistem suspensi. Hal ini yang mendasari penulis untuk melakukan penelitian terkait suspensi mobil Toyota Fortuner 4.0 V6 SR. Pada penelitian ini, terdapat dua tahap, yakni tahap pengujian dan tahap analisis. Tahap pengujian untuk mendapatkan persentase road holding yang digunakan dalam menentukan kriteria keamanan kendaraan. Pada tahap analisis dilakukan simulasi untuk mengetahui percepatan rms yang dialami penumpang dengan pemodelan Half Car memanjang. Selanjutnya dilakukan perancangan ulang pegas suspensi yang lebih baik dari segi keamanan dan kenyamanan. Dari penelitian ini diketahui bahwa desain dari mobil Toyota Fortuner mengutamakan kenyamanan untuk penggunaan di jalan perkotaan. Berdasarkan standar ISO 2631 menunjukkan bahwa respon suspensi redesain untuk jalan perkotaan menghasilkan kenyamanan yang lebih baik daripada suspensi aktual. Berdasarkan kriteria keamanan BEISSBARTH dari hasil pengujian menunjukkan bahwa suspensi mobil Toyota Fortuner termasuk dalam kategori kurang baik sedangkan hasil simulasi untuk suspensi aktual dan redesain termasuk dalam kategori cukup baik. Dari hasil penelitian didapatkan kekakuan pegas untuk suspensi depan (ksf = 44631,61 N/m dan (ksr = 53500 N/m untuk suspensi belakang.

  18. Analisis Spasial Kejadian Filariasi di Kabupaten Demak Jawa Tengah

    Directory of Open Access Journals (Sweden)

    Nurjazuli Nurjazuli

    2018-04-01

    Full Text Available Latar Belakang: Filariasis merupakan salah satu penyakit tular vektor yang kurang mendapatkan perhatian, termasuk kelompok Neglected Tropical Diseases (NTDs. Kabupaten Demak merupakan salah satu wilayah di Propinsi Jawa Tengah  yang merupakan daerah endemis filarisis (mf rate>1%. Kejadian filarisis di daerah ini diduga berkaitan dengan kondisi lingkungan fisik dan biologis (nyamuk yang mempunyai peran penting dalam penyebaran penyakit filarisis. Penelitian ini bertujuan untuk menemukan adanya penderita baru,  mengidentifikasi kondisi lingkungan fisik dan biologi yang berkaitan dengan sebaran filarisis di Kabupaten Demak. Matede: Penelitian ini merupakan penelitian observasional dengan rancangan cross-sectional. Sebanyak 30 kasus filariasis dijadikan indek kasus yang selanjutnya dipilih secara purposif sebanyak 140 yang tinggal di sekitar 30 kasus tersebut untuk dilakukan pengamblan darah jari. Observasi lingkungan dilakukan untuk mengidentifikasi kondisi lingkungan (breeding places dan resting places dari yang diduga sebagai nyamuk vektor filariasis. Penangkapan nyamuk dilakukan di sekitar rumah penderita filariasis. Pengukuran koordinat kasus filariais dilakukan dengan pesawat Geographic Positioning System (GPS. Pemeriksaan darah jadi jari dilakukan di Laboratorium Kesehatan Daerah (LABKESDA Propinsi Jawa Tengah. Sedang bedah nyamuk dilakukan di Balai Penelitian Vektor Penyakit Banjarnegara. Analisis data dlakukan secara deskriptif, analisis spasial dilakukan dengan software ArcGis 9.3. Hasil: Penelitian ini tidak menemukan penderita baru filarisis (mf rate=0%. Sebanyak 129 ekor nyamuk telah dilakukan pembedahan dengan hasil semuanya negatip cacing filaria. Hasil identifikasi nyamuk menemukan spesies nyamuk Culex quinquefasciatus merupakan nyamuk yang dominan (72,86% di lokasi penelitian.Terdapat breeding places (40% berupa genangan air terbuka (SPAL dan resting places (83,3% berupa semak-semak di sekitar rumah penderita. Analisis spasial

  19. Dinamiche e persistenza della povertà in Italia: Un’analisi con microdati panel di fonte ECHP

    OpenAIRE

    Francesco Devicienti; Valentina Gualtieri

    2004-01-01

    Questo articolo stima le probabilità di entrare e uscire dallo stato di povertà (poverty dynamics) e la sua persistenza in Italia negli anni ‘90, attingendo dalle fonti longitudinali dello European Community Household Panel, 1994-2001. Combinando le stime dei tassi di uscita con quelli di rientro, l’articolo propone una misura di persistenza che tiene conto degli spell ripetuti in povertà. L’analisi preliminare dei dati mostra che per circa il 46% della popolazione il reddito è al di sotto de...

  20. ANALISIS SPASIAL PADA KEJADIAN LUAR BIASA (KLB MALARIA DI DESA PANUSUPAN KECAMATAN REMBANG DAN DESA SIDAREJA KECAMATAN KALIGONDANG KABUPATEN PURBALINGGA

    Directory of Open Access Journals (Sweden)

    Widiarti Widiarti

    2015-01-01

    Full Text Available AbstrakMalaria seringkali muncul pada kejadian luar biasa (KLB maupun peningkatan kasus baik di Jawa maupun di luar Jawa. Dilaporkannya peningkatan kasus atau KLB malaria di Kabupaten Purbalingga menimbulkan pemikiran faktor-faktor apa yang mempengaruhi terjadinya KLB malaria. Tujuan penelitian adalah analisis spasial kasus malaria, konfirmasi vektor yang berperan dalam penularan malaria dan bioekologi nyamuk tersangka vektor. Lokasi penelitian di Desa Panusupan Kecamatan Rembang dan Desa Sidareja Kecamatan Kaligondang Kabupaten Purbalingga Jawa Tengah. Konfirmasi vektor dilakukan dengan elisa sporozoit dari semua nyamuk Anopheles sp yang diperoleh. Analisis kasus malaria digunakan metoda GIS dan dilanjutkan uji spatially weighted regression (spatial error model dengan GeoDa. Survei entomologi dilakukan sesuai standart penangkapan nyamuk oleh WHO. Hasil penelitian diperoleh informasi bahwa berdasarkan  elisa  sporozoit,  vektor  yang  berperan  di  Desa  Panusupan  Kecamatan  Rembang  adalah Anopheles maculatus hasil penangkapan hinggap pada manusia diluar rumah pada jam 18.00. Kejadian luar biasa malaria di Kabupaten Purbalingga, semula kasus import namun karena keberadaan vektor (daerah reseptif, sehingga terjadi penularan lokal. Analisis spasial kasus malaria di kedua desa mengelompok dan berdekatan dengan habitat perkembangbiakan An. maculatus yaitu ditepi aliran sungai. Mencermati vektor yang berperan di daerah KLB adalah An. maculatus dengan aktivitas sore sampai malam hari, maka perlu diinformasikan kepada masyarakat agar menjaga tidak kontak dengan nyamuk dan melindungi masyarakat dengan kelambu berinsektisida yang mempunyai daya lindung lama (LLIN sehingga dapat mengurangi terjadinya penularan.Kata Kunci : analisis spasial, KLB, Anopheles maculatus dan malariaAbstractMalaria outbreak or increase cases has came up very often inside or outside of Java Island. The increase malaria cases from Purbalingga Regency is reported

  1. ANALISIS BASIL SURVEI KEBUTUHAN INFORMASI DI WILAYAH WAMENA KAB. JAYAWIJAYA IRIAN JAYA

    Directory of Open Access Journals (Sweden)

    Sobari Sobari

    2011-12-01

    Full Text Available Survei kebutuhan informasi yang telah dilaksanakan di wilayah kabupaten Jayawijaya bertujuan untuk mengetahui subjek-subjek informasi yang dibutuhkan oleh masyarakat setempat serta untuk mengetahui usaha masyarakat dalam memenuhi kebutuhan tersebut. Hasil analisis survei menyimpulkan bahwa kebutuhan informasi masyarakat Jayawijaya lebih dominan pada subjek-subjek informasi bidang teknologi tepat guna, teknologi pedesaan atau teknologi sederhana. Subjek-subjek informasi lain yang juga banyak dibutuhkan adalah masalah sosial budaya, Kesehatan masyarakat, sistem peraturan perundang-undangan, hukum, kepemerintahan, administrasi, manajemen dan masalah perkantoran. Dalam memenuhi kebutuhan informasinya, masyarakat Jayawijaya masih mengandalkan perpustakaan sebagai tempat memperoleh bUkubuku atau bahan bacaan. Kebutuhan buku-buku pelajaran dan buku-buku bacaan anak-anak sekolah di wilayah kabupaten Jayawijaya, khususnya wilayah Wamena masih dirasakan sangat kurang.

  2. Analisis Persepsi Leadership Dan Kewirausahaan Dalam Mencapai Visi Teacherprenuership Dan Entrepreneurship (Studi Kasus Mahasiswa Fakultas Agama Islam Universitas Muhammadiyah Magelang)

    OpenAIRE

    Oktradiksa, Ahwy

    2015-01-01

    Penelitian ini bertujuan (1) untuk mengetahui persepsi leadership dalam mencapai visi teacherpreneurship dan entrepreneurship menurut mahasiswa Fakultas Agama Islam.(2) Untuk mengetahui analisis leadership dalam mencapai visi teacherpreneurship dan entrepreneurship di Fakultas Agama Islam. Penelitian ini adalah jenis penelitian lapangan studi kasus. Metode penelitian dengan analitis deskriptif, metode pengambilan sampel yang diambil dengan purposive sampling, teknik p...

  3. ANALISIS KUALITAS KEHIDUPAN KERJA, KINERJA, DAN KEPUASAN KERJA PADA CV DUTA SENENAN JEPARA

    Directory of Open Access Journals (Sweden)

    Noor Arifin

    2012-04-01

    Full Text Available Abstract: Analysis of Work Quality, Performance, and Job Satisfaction in CV. Duta Senenan Jepara. This study aims to analyze the effect of the quality work life of employees to their performance, analyze the effect of the quality of work life to the job satisfaction, and analyze the effect of the job satisfaction to employee performance. Variables used in this study are: quality of work Life developed by Wayne Cascio 1992; the performance of employees, developed by Elmuti and Kathawala, 1997; and variables Job Satisfaction, provided by Robbin, 1996 and Wexley et al, 1992. The sample of this study consists of 65 employees. The data Analysis were performed using structural equation modeling with partial least square approach. The result suggests that the quality of work life affects the performance; the satisfaction affects the employee performance; and the quality of working life has no effect on employee satisfaction.   Keywords :  quality of work life, on job satisfaction, employee performance   Abstrak: Analisis Kualitas Kehidupan, Kinerja, dan Kepuasan Kerja pada CV. Duta Senenan Jepara. Penelitian ini bertujuan untuk menganalisis pengaruh kualitas kehidupan kerja terhadap kinerja karyawan, menganalisis pengaruh kualitas kehidupan kerja terhadap kepuasan kerja, dan menganalisis pengaruh kepuasan kerja terhadap kinerja karyawan. Variabel yang digunakan dalam penelitian ini adalah: Kualitas Kehidupan Kerja, dari Cascio Wayne 1992. kemudian kinerja karyawan, dari Elmuti dan Kathawala, 1997, dan Kepuasan Kerja, yang dikembangkan oleh Robbin, 1996 serta Wexley et.al., 1992. Penelitian ini mengambil sampel 65 karyawan dari CV DUTA Senenan Jepara. Teknik analisis yang digunakan adalah Structural Equation Modeling (SEM dengan pendekatan Partial Least Square (PLS. Penelitian ini menyimpulkan bahwa kualitas kehidupan kerja sangat berpengaruh terhadap kinerjanya; kepuasan berpengaruh terhadap kinerja karyawan dan kualitas kehidupan kerja tidak

  4. Irradiation probe and laboratory for irradiated material evaluation

    International Nuclear Information System (INIS)

    Smutny, S.; Kupca, L.; Beno, P.; Stubna, M.; Mrva, V.; Chmelo, P.

    1975-09-01

    The survey and assessment are given of the tasks carried out in the years 1971 to 1975 within the development of methods for structural materials irradiation and of a probe for the irradiation thereof in the A-1 reactor. The programme and implementation of laboratory tests of the irradiation probe are described. In the actual reactor irradiation, the pulse tube length between the pressure governor and the irradiation probe is approximately 20 m, the diameter is 2.2 mm. Temperature reaches 800 degC while the pressure control system operates at 20 degC. The laboratory tests (carried out at 20 degC) showed that the response time of the pressure control system to a stepwise pressure change in the irradiation probe from 0 to 22 at. is 0.5 s. Pressure changes were also studied in the irradiation probe and in the entire system resulting from temperature changes in the irradiation probe. Temperature distribution in the body of the irradiation probe heating furnace was determined. (B.S.)

  5. Chapter 2: Irradiators

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2018-04-01

    The chapter 2 presents the subjects: 1) gamma irradiators which includes: Category-I gamma irradiators (self-contained); Category-II gamma irradiators (panoramic and dry storage); Category-III gamma irradiators (self-contained in water); Category-IV gamma irradiators (panoramic and wet storage); source rack for Category-IV gamma irradiators; product transport system for Category-IV gamma irradiators; radiation shield for gamma irradiators; 2) accelerators which includes: Category-I Accelerators (shielded irradiator); Category-II Accelerators (irradiator inside a shielded room); Irradiation application examples.

  6. ANALISIS PENGARUH LDR, NPL DAN ROA TERHADAP CAR PADA BANK PEMBANGUNAN DAERAH (BPD) SE- INDONESIA TAHUN 2007-2011

    OpenAIRE

    SAM, FATWAL

    2012-01-01

    2012 Analisis Pengaruh LDR, NPL, dan ROA terhadap CAR Pada Bank Pembangunan Daerah (BPD) Se-Indonesia Tahun 2007-2011 Analysis of Effect of Loan to Deposit Ratio, Non Performing Loan, and Return On Assets to the Capital Adequacy Ratio of the Regional Development Banks In Indonesia Period 2007-2011 Fatwal Sam Cepi Pahlevi Gamalca Penelitian ini bertujuan untuk menganalisis pengaruh variabel LDR, NPL dan ROA terhadap CAR. Data yang digunakan adalah publikasi laporan tahun...

  7. Analisis Kemanfaatan dan Kemudahan Penggunaan Aplikasi Manajemen Surat dengan Pendekatan Technology Acceptance Model pada PT. XYZ Surabaya

    Directory of Open Access Journals (Sweden)

    Aldioctavia Vicka Paramita

    2014-09-01

    Full Text Available PT. XYZ Surabaya merupakan salah satu perusahaan besar BUMN di Indonesia. Perusahaan BUMN ini bergerak dibidang aspek kelistrikan yang ada di area Jawa Timur. Dengan karya inovasinya, yaitu pengembangan Aplikasi Manajemen Surat bisnis yang semula dikerjakan secara manual menjadi berbasis web, tentu akan melahirkan sikap penerimaan atau penolakan dari user dalam proses penggunaannya. Sedangkan sebuah sistem informasi yang baik adalah yang dapat diterima oleh user dan dirasa memberikan kemudahan dan manfaat dalam proses penggunannya. Melalui tugas akhir ini akan diterapkan model sukses Fred Davis akan menilai faktor kemanfaatan dan kemudahan user Aplikasi Manajemen Surat  menggunakan metode analisis Partial Least Square untuk mengetahui korelasi tiap variabel dan hipotesis. Tugas akhir ini memverivikasi bahwa persepsi kemudahan penggunaan berpengaruh terhadap persepsi kemanfaatan penggunaan layanan AMS. Variasi pada penggunaan AMS dipengaruhi sebesar 24,5 persen oleh persepsi kemudahan, dan sisanya dipengaruhi oleh variabel lain. Pada persepsi minat sebesar 3,1 persen variasi dipengaruhi oleh persepsi sikap dan kemanfaatan, dan sisanya dipengaruhi oleh variabel lain. Persepsi kemanfaatan dan kemudahan mempengaruhi variasi dari persepsi sikap sebesar 94,5 persen. Sedangkan variasi dari persepsi kenyataan, sebesar 57,3 persen diperngaruhi oleh persepsi minat dan sisanya 43,7 persen dipengaruhi oleh variabel yang lain.Analisis Kemanfaatan dan Kemudahan Penggunaan Aplikasi Manajemen Surat dengan Pendekatan Technology Acceptance Model pada PT. XYZ Surabaya

  8. Representasi Maskulinitas Dalam Iklan Televisi Pond’s Men #Lelakimasakini (Analisis Semiotika Roland Barthes Terhadap Representasi Maskulinitas

    Directory of Open Access Journals (Sweden)

    Friska Dewi Yuliyanti

    2017-07-01

    Full Text Available This research aims to know the meaning of denotation, the connotation and the myth or ideology in television commercials POND'S Men that represent the masculine with #LelakiMasaKini edition. The method used in this research is the Semiotic analysis methods. The Semiotic analysis used in this research is the Semiotic Roland Barthes. The results of this research show that there are; meaning denote, the connotation and the myth or ideology in television commercials POND'S #LelakiMasaKini. The results obtained from the signs of the dominant in the preview scenes that are taken in accordance with the criteria that have been determined. Advertising on Rio Dewanto version described three meaning denotes, three meaning of the connotations and three myths. On the version of the advertisement, Keenan Pearce described three meaning denotes, three the meaning of the connotations and three myths or ideologies and on the version of the Marshall Sastra described three meaning denotes, three the meaning of the connotations and 3 myths or ideologies. Concluded the side or the form of masculinity is promoted of the physical appearance of the type of men who tend to metrosexual, the dream of women, the leader success, lack men who think creatively and have hobbies. Penelitian ini bertujuan untuk mengetahui makna denotasi, konotasi serta mitos atau ideologi dalam iklan televisi POND’S Men yang merepresentasikan maskulinitas dengan edisi #LelakiMasaKini. Metode yang digunakan dalam penelitian ini adalah metode analisis semiotik. Analisis Semiotik yang digunakan dalam penelitian ini adalah analisis semiotik Roland Barthes. Hasil dari penelitian ini menunjukkan bahwa terdapat makna denotasi, konotasi serta mitos atau ideologi pada iklan televisi POND’S Men #LelakiMasaKini. Hasil itu diperoleh dari tanda-tanda dominan pada cuplikan adegan-adegan yang diambil sesuai dengan kriteria yang telah ditentukan. Pada iklan versi Rio Dewanto digambarkan 3 makna denotasi, 3

  9. PENERAPAN QFD DAN ANALISIS SWOT UNTUK MENETAPKAN STRATEGI PENINGKATAN KUALITAS PRODUK SAYURAN SEGAR

    Directory of Open Access Journals (Sweden)

    Enny Purwati Nurlaili

    2012-02-01

    Full Text Available Makalah ini memaparkan hasil penelitian menentukan strategi untuk meningkatkan kualitas produk sayuran segar dari Perusahaan Agroindustri PT Z.  Strategi perbaikan kualitas dirumuskan berdasar keinginan pelanggan, atribut kunci dan membandingkan evaluasi faktor internal dan eksternal. Keinginan pelanggan dirumuskan dengan metode QFD sedangkan penentuan strategi menggunakan analisa SWOT.. Analisis QFD menunjukkan bahwa kemampuan perusahaan dalam memenuhi keinginan dan harapan pelanggan secara keseluruhan sudah cukup memuaskan konsumen. Sedangkan strategi yang paling tepat digunakan adalah stategi S – O yaitu melakukan peningkatan kualitas produk yang dihasilkan terutama upaya mempertahankan kesegaran dan jaminan kemanan pangan melalui penerapan  HACCP Kata Kunci :        Agroindustry, QFD, Formulasi Strategi,  Sayuran Segar

  10. Environmental analysis of natural gas life cycle; Analisi ambientale del ciclo di vita del gas naturale

    Energy Technology Data Exchange (ETDEWEB)

    Riva, A.; D' Angelosante, S.; Trebeschi, C. [Snam SpA, Rome (Italy)

    2000-12-01

    Life Cycle Assessment is a method aimed at identifying the environmental effects connected with a given product, process or activity during its whole life cycle. The evaluation of published studies and the application of the method to electricity production with fossil fuels, by using data from published databases and data collected by the gas industry, demonstrate the importance and difficulties to have reliable and updated data required for a significant life cycle assessment. The results show that the environmental advantages of natural gas over the other fossil fuels in the final use stage increase still further if the whole life cycle of the fuels, from production to final consumption, is taken into account. [Italian] L'analisi del ciclo di vita e' una metodologia che consente di identificare gli effetti ambientali associati ad un prodotto, processo o attivita' lungo il loro ciclo di vita. La valutazione di studi pubblicati e l'applicazione della metodologia alla produzione di energia elettrica da combustibili fossili, utilizzando dati provenienti da banche dati di letteratura e raccolti dall'industria del gas, dimostrano l'importanza e la difficolta' di avere a disposizione dati affidabili ed aggiornati, necessari per un'analisi significativa del ciclo di vita. I risultati mostrano che i vantaggi ambientali del gas naturale rispetto agli altri combustibili fossili nella fase di utilizzo finale, aumentano ulteriormente se si considera l'intero ciclo di vita dei diversi combustibili, dalla produzione al consumo finale.

  11. Analisi della relazione tra temperamento, stati psicobiosociali e variabili psicofisiche rispetto ai diversi compiti e strategie metodologiche

    OpenAIRE

    Montemurro, Francesco Paolo

    2012-01-01

    L’attività fisica produce effetti benefici a livello mentale (Biddle et al.,2004) e sembra agire sull’emozione modificando attitudini e motivazioni verso la pratica motoria (Digelidis et al., 2003) a partire da sensazioni come il piacere o la noia del fare (Spray et al., 1999). Da questi presupposti il progetto che comprendeva l’analisi di due studi volti a verificare gli effetti dell’attività motoria e sportiva in ambito scolastico, sui comportamenti di adattamento sociale e self efficac...

  12. Micro-grid platform based on NODE.JS architecture, implemented in electrical network instrumentation

    Science.gov (United States)

    Duque, M.; Cando, E.; Aguinaga, A.; Llulluna, F.; Jara, N.; Moreno, T.

    2016-05-01

    In this document, I propose a theory about the impact of systems based on microgrids in non-industrialized countries that have the goal to improve energy exploitation through alternatives methods of a clean and renewable energy generation and the creation of the app to manage the behavior of the micro-grids based on the NodeJS, Django and IOJS technologies. The micro-grids allow the optimal way to manage energy flow by electric injection directly in electric network small urban's cells in a low cost and available way. In difference from conventional systems, micro-grids can communicate between them to carry energy to places that have higher demand in accurate moments. This system does not require energy storage, so, costs are lower than conventional systems like fuel cells, solar panels or else; even though micro-grids are independent systems, they are not isolated. The impact that this analysis will generate, is the improvement of the electrical network without having greater control than an intelligent network (SMART-GRID); this leads to move to a 20% increase in energy use in a specified network; that suggest there are others sources of energy generation; but for today's needs, we need to standardize methods and remain in place to support all future technologies and the best option are the Smart Grids and Micro-Grids.

  13. ANALISIS MODA KEGAGALAN DENGAN PENDEKATAN RELIABILITY CENTERED MAINTENANCE (RCM (Studi kasus Baking Section Mesin Imfori PT Nissin Biskuit Indonesia

    Directory of Open Access Journals (Sweden)

    Sri Hartini

    2012-02-01

    Full Text Available Reliability Centered Maintenance (RCM adalah suatu pendekatan perawatan yang berbasis pada upaya menjamin keandalan mesin. Dengan pendekatan ini, perawatan ditujukan untuk menjamin agar asset terus menerus mencapai kemampuan dasarnya. Dalam penelitian dilakukan analisis fungsi sistem yang tepat terhadap Baking Section mesin Imaforni PT Nissin Biskuit Indonesia melalui pendekatan RCM untuk mengetahui moda kegagalan yang dapat menyebabkan sistem kehilangan fungsinya. Kata Kunci : Fungsi Sistem,Moda Kegagalan,Reliability Centered Maintenance.

  14. ANALISIS SISTEM ANTRIAN TRANSPORTASI BUSWAY DI HALTE PULOGADUNG DAN DUKUH ATAS

    Directory of Open Access Journals (Sweden)

    Umi Marfuah

    2015-02-01

    Full Text Available Salah satu daerah Jakarta yang memiliki tingkat mobilitas yang cukup sibuk yaitu di daerah Pulogadung yang merupakan kawasan industri dan di daerah Dukuh Atas sekitar Sudirman, yang merupakan kawasan perkantoran di pusat kota. Minat masyarakat akan transportasi busway sebagai sarana transportasi umum dalam kegiatan hari – harinya sangat besar. Hal tersebut menyebabkan meningkatnya jumlah pengguna busway setiap tahunnya, namun Unit Pengelola Transjakarta Busway belum dapat memaksimalkan pelayanan yang dapat diberikan sehingga terjadi penumpukkan penumpang pada halte Pulogadung dan Dukuh Atas, terutama pada hari – hari  kerja di jam sibuk. Penelitian ini didasari pada perbaikan sistem antrian yang ada pada saat ini, sehingga didapatkan solusi untuk mengatasi masalah antrian pada kedua halte tersebut dengan efisien waktu pelayanan sebesar 13%. Model antrian yang digunakan yaitu Single Phase-Single Channel dengan analisis perbaikaanya disimulasikan dengan Promodel.   Kata kunci : Sistem, Antrian, Promodel.

  15. Analisis Vegetasi di Hutan Mbeji Daerah Wonosalam Jombang

    Directory of Open Access Journals (Sweden)

    Anita Munawwaroh

    2016-03-01

    Full Text Available Analisis vegetasi terhadap hutan perlu dilakukan untuk mengetahui keanekaragaman hayati yang terdapat di hutan tersebut sehingga mempermudah didalam melakukan pemeliharaan dan pemberdayaan hutan.Tujuan dari penelitian ini adalah untuk mengetahui keanekaragaman hayati dan struktur vegetasi (frekuensi, kerapatan, dominansi, dan Indeks Nilai Penting di hutan mbeji, Wonossalam, Jombang. Pada penelitian ini digunakan metode point centered quarter. Pennelitian dilakukan pada bulan Mei 2015. Hasil penelitian menujukkan padaHutan Mbeji terdapat 11 jenis pohon yang teridentifikasi dan 15 spesies tumbuhan, dimana ada 10 spesies yang telah teridentifikasiNilai penting  tumbuh-tumbuhan di Hutan Mbeji di daerah Wonosalam Jombang  pada tingkat pohon paling tinggi adalah pohon randu (Ceiba petandra  sebesar 57,42 % sedangkan nilai INP paling rendah dari jenis pohon andong (Rhadamnia cinerea yaitu sebesar 6,06 %. Pada sapling nilai penting yang paling tinggi adalah talas (Colocasia esculenta yaitu sebesar 49,23 %. Sedangkan, nilai INP paling rendah dari jenis nanas (Ananas comosus, nangka (Artocarpus heterophyllus, tapak liman (Elephantopus scaber, semak A, semak B, semak C, semak E, dan semak F yaitu sebesar 6,35 %. Tingginya nilai INP menunjukkan bahwa jenis-jenis tersebut dapat menyesuaikan diri dengan lingkungan sekitarnya yang lebih baik dibanding jenis lainnya.

  16. Analisis Cost-Volume-Profit Kaitannya dengan Perencanaan Laba

    Directory of Open Access Journals (Sweden)

    Rian Andriani

    2018-01-01

    Full Text Available Tujuan penelitian  ini adalah untuk menganalisis cost, volume, profit Break Event Point dan Margin Of Safety L.A English Course Baleendah Bandung pada kuartal I – IV. Metode penelitian yang digunakan adalah metode penelitian kuntitatif deskriptif. Teknik pengumpulan data menggunakan studi pustaka, observasi, wawancara, dan dokumentasi yang memiliki hubungan dengan pokok permasalahan. Teknik analisis data yang digunakan metode regresi kuadrat terkecil, break event point dan margin of safety.  Hasil menunjukan, biaya tertinggi terdapat pada kuartal I, volume penjualan  tertinggi terdapat pada kuartal I, laba tertinggi terdapat pada kuartal I, Break Event Point tertinggi terdapat pada kuartal I. Sedangkan Margin of safety (% tertinggi pada kuartal IV yaitu 91.9%. Masalah yang timbul dalam  perencanaan  laba yaitu pertama  pendapatan L.A English Course  naik turun  dalam satu  tahunnya, kedua  kurangnya promosi untuk beberapa program kecuali program regular. Upaya dalam mengatasi masalah yang timbul di L.A English Course yaitu pertama memberikan gratis biaya daftar, dan memberi voucher untuk siswa L.A yang memasukan siswa baru., kedua membagikan brosur, dan menawarkan program L.A. dengan melakukan follow up semua nomor telepon tamu yang pernah berkunjung.

  17. Food irradiation

    International Nuclear Information System (INIS)

    Sato, Tomotaro; Aoki, Shohei

    1976-01-01

    Definition and significance of food irradiation were described. The details of its development and present state were also described. The effect of the irradiation on Irish potatoes, onions, wiener sausages, kamaboko (boiled fish-paste), and mandarin oranges was evaluated; and healthiness of food irradiation was discussed. Studies of the irradiation equipment for Irish potatoes in a large-sized container, and the silo-typed irradiation equipment for rice and wheat were mentioned. Shihoro RI center in Hokkaido which was put to practical use for the irradiation of Irish potatoes was introduced. The state of permission of food irradiation in foreign countries in 1975 was introduced. As a view of the food irradiation in the future, its utilization for the prevention of epidemics due to imported foods was mentioned. (Serizawa, K.)

  18. ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI ADOPSI APLIKASI UBER SEBAGAI PENYEDIA JASA TRANSPORTASI DI SURABAYA

    Directory of Open Access Journals (Sweden)

    Edwin Hendrani

    2017-01-01

    Full Text Available Seiring berjalannya waktu, Teknologi Informasi dan Komunikasi (TIK di dunia ini semakin berkembang dengan pesat. Permintaan masyarakat akan kebutuhan jasa transportasi semakin tinggi. Kemajuan internet dan canggihnya telepon genggam semakin lama semakin canggih, yang membuat lebih nyaman dan efisiensi untuk memanjakan masyarakat. Dari fenomena tersebut lahirlah Uber. Penelitian ini menggunakan teori Technology Acceptance Model (TAM dengan populasi user Uber Kota Surabaya. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi adopsi aplikasi Uber sebagai penyedia jasa Transportasi di Surabaya. Hasil yang diperoleh setelah di analisis oleh peneliti adalah kepercayaan pengguna dalam mengadopsi aplikasi Uber yang sangat berpengaruh signifikan terhadap keinginan seseorang untuk menggunakan aplikasi Uber.

  19. Food irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Gruenewald, T

    1985-01-01

    Food irradiation has become a matter of topical interest also in the Federal Republic of Germany following applications for exemptions concerning irradiation tests of spices. After risks to human health by irradiation doses up to a level sufficient for product pasteurization were excluded, irradiation now offers a method suitable primarily for the disinfestation of fruit and decontamination of frozen and dried food. Codex Alimentarius standards which refer also to supervision and dosimetry have been established; they should be adopted as national law. However, in the majority of cases where individual countries including EC member-countries so far permitted food irradiation, these standards were not yet used. Approved irradiation technique for industrial use is available. Several industrial food irradiation plants, partly working also on a contractual basis, are already in operation in various countries. Consumer response still is largely unknown; since irradiated food is labelled, consumption of irradiated food will be decided upon by consumers.

  20. ANALISIS MODEL KEPUASAN TERHADAP PEMBELIAN ULANG

    Directory of Open Access Journals (Sweden)

    Naili Farida

    2014-09-01

    Full Text Available Tujuan penelitian ini yaitu untuk menguji pengaruh brand equity, nilai pelanggan dan lifestyle yang dimediasi kepuasan konsumen terhadap pembelian ulang produk gadget di Kota Semarang. Responden dalam penelitian ini adalah seluruh konsumen yang telah melakukan pembelian produk gadget merek Samsung, sebanyak 120 orang. Teknik sampling yang digunakan yaitu purposive sampling. Teknik analisis yang digunakan yaitu Partial Least Square (PLS. Hasil penelitian menunjukkan bahwa terdapat pengaruh brand equity terhadap kepuasan, namun dalam konteks lifestyle dan nilai pelanggan tidak ada pengaruh terhadap kepuasan. Sedangkan kepuasan menunjukkan adanya pengaruh terhadap pembelian ulang. Diharapkan dari hasil penelitian ini mampu meningkatkan pembelian ulang melalui brand equity, lifestyle dan nilai pelanggan dalam konteks kepuasan. The objective of the research was to test the influence of brand equity, customer value and lifestyle which were mediated by consumer satisfaction toward re-purchasing of gadget products in Semarang. The respondents of the study were all consumers who have purchased Samsung gadget products. It was a purposive sampling study with 120 respondents. The data were analyzed by Partial Least Square (PLS. The result of the study showed that there was an influence of brand equity toward satisfaction, but in the lifestyle context and customer value did not give any influence toward satisfaction. Whereas; the satisfaction gave influence toward re-purchase. It is expected that this study can increase the repurchasethrough brand equity, lifestyle and customer values in the satisfaction context.

  1. Analisis Penerapan E-Government di Kabupaten Sragen

    Directory of Open Access Journals (Sweden)

    Yan Andriariza AS

    2013-09-01

    Full Text Available ABSTRAK Kabupaten Sragen merupakan salah satu pemerintah kabupaten yang menerapkan e-government dengan baik, dan merupakan kabupaten yang menjadi percontohan dalam suksesnya penerapan e-government. Karenanya perlu untuk dilakukan analisis penerapan e-government di Kabupaten Sragen, sebagai contoh bagi daerah lain dalam membangun e-government di daerah tersebut. Analisa yang dilakukan antara lain melihat seberapa jauh penerapan G2C, G2B dan G2G di Pemerintah Kabupaten Sragen. Selain itu juga dilakukan analisa menggunakan The UN Web Measure Index, dan analisa terakhir melakukan analisa deskriptif untuk 5 faktor kesuksesan penerapan e-government, yaitu Hukum dan Peraturan, Struktur Organisasi, Proses Bisnis, Teknologi Informasi dan Visi, Objektif dan Strategi. Dari hasil analisis diperoleh kesimpulan bahwa Kabupaten Sragen telah menerapkan G2B dan G2G, serta berada pada tahap awal penerapan G2C, selain itu Kabupaten Sragen juga telah mencapai pemerintahan yang online, tanpa kertas dan transparan. Implementasi e-government di kabupaten Sragen tersebut dapat dikatakan sukses karena telah memenuhi beberapa faktor dalam mencapai kesuksesan implementasi e-government, yaitu hukum dan peraturan, struktur organisasi, teknologi informasi dan visi, objektif dan strategi. Bila dilihat berdasarkan UN Web Measured Index, Kabupaten Sragen telah mencapai tahap 4. Saran yang dapat diberikan melalui penelitian ini adalah untuk unit kerja yang menangani TIK di Kabupaten Sragen akan lebih baik bila dipegang oleh unit kerja setingkat eselon 2 dan perlunya SOP dan peraturan tambahan terkait TIK di Kabupaten Sragen. ABSTRACT Sragen is one of the districts that implement well e-government, and being a model for the successful implementation of e-government. It is necessary to do the analysis of the application of e-government in Sragen, as an example for other regions in developing e-government in the area. Analysis was carried out to see how far the application of G2C

  2. Analisis Persepsi Leadership dan Kewirausahaan dalam Mencapai Visi Teacherprenuership dan Entrepreneurship (Studi Kasus Mahasiswa Fakultas Agama Islam Universitas Muhammadiyah Magelang)

    OpenAIRE

    Ahwy Oktradiksa

    2015-01-01

    Penelitian ini bertujuan (1) untuk mengetahui persepsi leadership dalam mencapai visi teacherpreneurship dan entrepreneurship menurut mahasiswa Fakultas Agama Islam.(2) Untuk mengetahui analisis leadership dalam mencapai visi teacherpreneurship dan entrepreneurship di Fakultas Agama Islam. Penelitian ini adalah jenis penelitian lapangan studi kasus. Metode penelitian dengan analitis deskriptif, metode pengambilan sampel yang diambil dengan purposive sampling, teknik pengambilan data dengan me...

  3. Analisis “Brand Equity” Siaran Berita Stasiun Televisi Swasta Indonesia

    Directory of Open Access Journals (Sweden)

    Arif Sugiono

    2004-12-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui keadaan berbagai merek siaran berita stasiun televisi swasta berdasarkan dimensi ekuitas mereknya, dengan memfokuskan pada empat dimensi ekuitas merek, yang meliputi loyalitas merek, kesadaran merek, persepsi kualitas, dan asosiasi merek. Metode yang digunakan metode deskriptif, dengan analisis data menggunakan tabulasi dan teknik skala. Hasil penelitian dari dimensi loyalitas merek tiga besar siaran berita secara berurutan adalah Buser, Patroli dan Liputan 6 Petang. Dari dimensi Kesadaran Merek tiga siaran berita yang disebut adalah Buser, Patroli dan Liputan 6 Petang. Dari segi asosiasi merek, Buletin Siang dan Liputan 6 Siang (44%, diasosiasikan sebagai siaran berita yang penyajiannya cepat. Patroli (62% diasosiasikan siaran berita yang penyajiannya akurat (benar dan obyektif Info Manca Negara (56% diasosiasikan sebagai siaran berita yang penyajiannya cukup menarik. Dari dimensi persepsi kualitas yang dijadikan pedoman adalah, kecepatan berita 31%, keakuratan aberita 36%, penyajian berita 33%, dengan urutan merek siaran berita Liputan 6 Siang, Buser, dan Patroli.

  4. Analisis Framing Pemberitaan Kisruh Partai Golkar Pasca Keputusan Menkumham Dalam Program Dialog Primetime News Metro TV Dan Kabar Petang TVOne

    Directory of Open Access Journals (Sweden)

    Etika Widya Kusumadewi

    2016-12-01

    Full Text Available In the span of 2014 to 2015, the Golkar Party experienced a tumultuous duality of leadership between Aburizal Bakrie and Agung Laksono version. The Government through the Ministry of Justice and Human Rights issued a decree stating Golkar Party Agung Laksono version is a legitimate stewardship. Two national television news station, Metro TV and TVOne, which are both owned by political party leaders, also 'warm' to the conflict on both sides. This study aims to understand, analyze, describe and compare dialog program Primetime News Metro and Evening News TVOne in framing news Golkar chaotic post-issuance of a decree by the Minister of Justice and Human Rights. Data analysis techniques used in this research is the analysis method with the paradigm framing or constructionist approach. This study uses a model framing analytical approach by using categorization Murray Edelman. From the results of research show can be quite impartial Metro while TVOne are beyond reasonable limits. Both seemed to favor and do not promote objectivity. Media ownership is considered to impact content that do both. Pada rentang waktu 2014 hingga 2015 Partai Golkar mengalami kisruh dualisme kepemimpinan yakni Golkar Aburizal Bakrie versi Munas Bali dan Golkar Agung Laksono versi Munas Jakarta. Menkumham kemudian mengeluarkan SK yang semakin membuat panas tubuh partai. Dua media televisi nasional, Metro TV dan TVOne, yang keduanya dimiliki oleh pimpinan partai politik, turut ‘menghangatkan’ konflik kedua kubu. Penelitian ini bertujuan untuk memahami, menganalisis, mendeskripsikan serta menbandingkan program dialog Primetime News Metro TV dan Kabar Petang TVOne dalam membingkai pemberitaan kisruh partai Golkar pasca dikeluarkannya SK Menkumham yang isinya menyatakan Golkar Agung Laksono adalah kepengurusan yang sah. Teknik analisis data yang digunakan dalam penelitian ini adalah metode analisis framing dengan paradigma atau pendekatan konstruksionis. Penelitian ini

  5. ANALISIS PARTISIPASI MASYARAKAT DALAM PEMBANGUNAN FISIK (STUDI KASUS DI DESA PUNGUT HILIR, KECAMATAN AIR HANGAT TIMUR, KABUPATEN KERINCI

    Directory of Open Access Journals (Sweden)

    vivi herlina

    2017-10-01

    Full Text Available Peran masyarakat untuk memujudkan pembangunan fisik sangat penting sekali. Penelitian ini menggunakan metode purposive sampling. Hasil penelitian ini menunjukkan bahwa masyarakat Desa Pungut Hilir, Kecamatan Air Hangat Timur, Kabupaten Kerinci telah diikutsertakan dalam proses pembangunan desa. Namun, terdapat beberapa warga yang tidak ingin ikut terlibat dalam proses pembangunan tersebut. Umumnya masyarakat telah dilibatkan dalam kegiatan pertemuan desa. Terdapat lima indikator analisis partisipasi yang digunakan, yaitu indikator prakarsa/inisiatif, pembiayaan, pengambilan keputusan, mobilisasi tenaga, dan pelaksanaan pembangunan.

  6. ANALISIS SEBARAN RADIONUKLIDA PADA KONDISI NORMAL UNTUK REAKTOR AEC 1000 MW

    Directory of Open Access Journals (Sweden)

    Sri Kuntjoro

    2015-03-01

    Full Text Available Telah dilakukan analisis sebaran radionuklida pada reaktor daya Atomic Energy Agency (AEC 3568 MWTh, setara dengan 1000 Mwe untuk kondisi operasi normal. Analisis dilakukan untuk dua reaktor yang terpisah sejauh 500 m dan sudut 90o satu dengan yang lain. Langkah awal dalam melakukan analisis adalah menentukan suku sumber reaktor menggunakan program komputer ORIGEN2 dan EMERALD NORMAL. ORIGEN2 digunakan untuk menentukan inventori radionuklida yang terdapat di reaktor. Selanjutnya dengan dengan menggunakan program EMERALD NORMAL dihitung suku sumber yang sampai ke cerobong reaktor. Untuk menganalisis dosis yang diterima penduduk dilakukan dengan menggunakan program PC-CREAM. Perhitungan dilakukan untuk satu dan dua PLTN di calon tapak PLTN. Hasil yang diperoleh adalah sebaran radionuklida terbesar untuk satu PLTN pada jarak 1 km dan kearah zona 9 (191,25o dan untuk dua PLTN pada jarak 1 km dan kearah zona 10 (213,75o. Radionuklida yang sampai ke penduduk melalui dua alur yaitu alur makanan dan hirupan. Untuk alur makanan berasal dari radionuklida I-131, dan terbesar melalui alur produk susu sebesar 53,40 % untuk satu maupun dua PLTN . Untuk alur hirupan ranionuklida pemberi kontribusi paparan terbesar berasal dari Kr-85m sebesar 53,80 %. Dosis total terbesar yang diterima penduduk terdapat pada jarak 1 Km untuk bayi yaitu sebesar 4,10 μSi dan 11,26 μSi untuk satu dan dua PLTN. Hasil ini sangat kecil dibandingkan dengan batas dosis yang diijinkan oleh badan pengawas (BAPETEN untuk penduduk yaitu sebesar 1 mSi. Kata Kunci : Reaktor daya, komputer code, radionuklida, alur makanan, hirupan   Analysis for radionuclide dispersion for the Atomic Energy Agency (AEC 3568 MWth Power Reactor, equal to the 1000 MWe at normal condition has been done. Analysis was done for two piles that is separated by 500 m distance and angle of 90o one to other. Initial pace in doing the analysis is to determine reactors source term using ORIGEN2 and EMERALD NORMAL

  7. Prenatal Diagnosis and Molecular Analysis of a Large Novel Deletion (- -JS) Causing α0-Thalassemia.

    Science.gov (United States)

    Cao, Jinru; He, Shuzhen; Pu, Yudong; Liu, Jingjing; Liu, Fuping; Feng, Jun

    α-Thalassemia (α-thal) is a very common single gene hereditary disease caused by large deletions or point mutations of the α-globin gene cluster in tropical and subtropical regions of the world. Here, we report for the first time, a novel large α-thal deletion in a Chinese family from Jiangsu Province, People's Republic of China (PRC), which removes almost the entire α2 and α1 genes from the α-globin gene cluster. Thus, it was named the Jiangsu deletion (- - JS ) on the α-globin gene cluster causing α 0 -thal. Heterozygotes for this deletion showed an α-thal trait phenotype with reduced mean corpuscular volume (MCV) and mean corpuscular hemoglobin (Hb) (MCH) levels. The sequencing results showed that a 2538 bp deletion (NG_000006.1: g.35801_38338) existed in this novel genotype on the basis of -α 4.2 (leftward), indicating a deletion of about 6.8 kb from the α-globin cluster. In addition, a 29 bp sequence was inserted into the deletion during the recombination events that led to this deletion. Through pedigree analysis, we knew that the proband inherited the novel allele from his mother.

  8. Food irradiation

    International Nuclear Information System (INIS)

    Lindqvist, H.

    1996-01-01

    This paper is a review of food irradiation and lists plants for food irradiation in the world. Possible applications for irradiation are discussed, and changes induced in food from radiation, nutritional as well as organoleptic, are reviewed. Possible toxicological risks with irradiated food and risks from alternative methods for treatment are also brought up. Ways to analyze weather food has been irradiated or not are presented. 8 refs

  9. Efektivitas dan Kendala Pembelajaran Sains Berbasis Inkuiri terhadap Capaian Dimensi Kognitif Siswa: Meta Analisis

    Directory of Open Access Journals (Sweden)

    Abdurrahman Abdurrahman

    2017-06-01

    teknologi informasi. Pembelajaran berbasis inkuiri sering disusun dalam fase penyelidikan yang berfokus untuk membangun kemampuan sains bagi para siswa. Namun, variasi yang berbeda mengenai makna kompetensi penyelidikan sering kita temukan di berbagai literatur. Artikel ini berfokus untuk mengidentifikasi dan meringkas fitur inti dari pembelajaran berbasis inkuiri melalui metode meta analisis, mengkaji literatur secara sistematis dan mengembangkan proses penyelidikan yang disintesis dengan menggabungkan kekuatan kerangka kerja pembelajaran berbasis inkuiri yang ada untuk meningkatkan prestasi belajar siswa. Kajian ini dilakukan dengan menggunakan basis data dari Web of Science dan ERIC (Education Resources Information Center; Sebanyak 15 artikel yang menjelaskan tahap penyelidikan atau keseluruhan proses penyelidikan dipilih berdasarkan kriteria pencarian yang spesifik. Analisis terhadap artikel menghasilkan identifikasi lima fase penyelidikan umum yang dapat berbeda secara istilah satu sama lainnya yaitu: Orientasi, Konseptualisasi, Investigasi, Diskusi dan Kesimpulan. Disamping itu, hampir seluruh pembelajaran berbasis inkuiri biasanya berakhir dengan fase Kesimpulan. Berdasarkan analisis di seluruh hasil penelitian menunjukkan bahwa pembelajaran berbasis inkuiri telah berhasil menunjukkan peningkatan penguasaan aspek kognitif siswa secara signifikan.

  10. Irradiation proctitis

    International Nuclear Information System (INIS)

    Minami, Akira

    1977-01-01

    Literatures on late rectal injuries are discussed, referring to two patients with uterine cervical cancer in whom irradiation proctitis occurred after telecobalt irradiation following uterine extirpation. To one patients, a total of 5000 rads was irradiated, dividing into 250 rads at one time, and after 3 months, irradiation with a total of 2000 rads, dividing into 200 rads at one time, was further given. In another one patient, two parallel opposing portal irradiation with a total of 6000 rads was given. About a year after the irradiation, rectal injuries and cystitis, accompanying with hemorrhage, were found in both of the patients. Rectal amputation and proctotoreusis were performed. Cystitis was treated by cystic irradiation in the urological department. Pathohistological studies of the rectal specimen revealed atrophic mucosa, and dilatation of the blood vessels and edema in the colonic submucosa. Incidence of this disease, term when the disease occurs, irradiation dose, type of the disease, treatment and prevention are described on the basis of the literatures. (Kanao, N.)

  11. Irradiation proctitis

    Energy Technology Data Exchange (ETDEWEB)

    Minami, A [Osaka Kita Tsishin Hospital (Japan)

    1977-06-01

    Literatures on late rectal injuries are discussed, referring to two patients with uterine cervical cancer in whom irradiation proctitis occurred after telecobalt irradiation following uterine extirpation. To one patients, a total of 5000 rads was irradiated, dividing into 250 rads at one time, and after 3 months, irradiation with a total of 2000 rads, dividing into 200 rads at one time, was further given. In another one patient, two parallel opposing portal irradiation with a total of 6000 rads was given. About a year after the irradiation, rectal injuries and cystitis, accompanying with hemorrhage, were found in both of the patients. Rectal amputation and proctotoreusis were performed. Cystitis was treated by cystic irradiation in the urological department. Pathohistological studies of the rectal specimen revealed atrophic mucosa, and dilatation of the blood vessels and edema in the colonic submucosa. Incidence of this disease, term when the disease occurs, irradiation dose, type of the disease, treatment and prevention are described on the basis of the literatures.

  12. IDENTIFIKASI TEKNIK-TEKNIK PENGUBAHAN TINGKAH LAKU DALAM PENERAPAN PEMIKIRAN IBNU QOYYIM AL-JAUZIYYAH UNTUK PENGENTASAN KORBAN SEKS BEBAS DAN HOMOSEKS (KAJIAN ANALISIS HERMENEUTIKA BERSUSUN

    Directory of Open Access Journals (Sweden)

    Aswar Aswar

    2016-02-01

    Full Text Available The purposes of this research were to obtain (1 Descriptive-interpretative information  related to the intervention targets of behavior modification, (2 Descriptive-interpretative information  related with the analysis and diagnosis, and (3 Descriptive-interpretative understanding on each form of treatment that can be used as a technique of behavior modification for freesex and homosexual. Data were collected through a text document of Ibnu Qoyyim al-Jauziyyah thought, observation and interview with research subjects in the field. The study used a qualitative approach with multilevel hermeneutic analysis. Results of the study were: (1 Intervention target of modification behavior focusing on thought/belief modification; (2 analysis and diagnosis around the unhealthy thoughts/beliefs and habit/action; (3 it was founded treatment form to alleviate freesex victim and homosexual in the form of mind intervention techniques, lust disorder alleviation techniques, homosexual alleviation techniques, and worship as an alleviation techniques. Tujuan penelitian ini untuk memperoleh (1 keterangan deskriptif-interpretif terkait sasaran intervensi pengubahan tingkah laku, (2 keterangan deskriptif-interpretif terkait analisis dan diagnosis, dan (3 pemahaman deskriptif-interpretif pada tiap bentuk perlakuan yang dapat dijadikan sebagai teknik pengubahan tingkah laku seks bebas dan homoseks. Data dikumpulkan melalui dokumen teks pemikiran Ibnu Qoyyim al-Jauziyyah, observasi dan interviu subjek terteliti lapangan. Penelitian menggunakan pendekatan kualitatif dengan analisis hermeneutika bersusun. Hasil penelitian adalah (1 sasaran intervensi pengubahan tingkah laku berfokus di pengubahan pikiran/keyakinan; (2 analisis dan diagnosis berkisar pada pikiran/keyakinan dan kebiasaan/perbuatan yang tidak sehat; (3 ditemukan bentuk perlakuan dalam pengentasan korban seks bebas dan homoseks berupa teknik intervensi pikiran, teknik pengentasan gangguan syahwat, teknik

  13. Food irradiation

    International Nuclear Information System (INIS)

    Soothill, R.

    1987-01-01

    The issue of food irradiation has become important in Australia and overseas. This article discusses the results of the Australian Consumers' Association's (ACA) Inquiry into food irradiation, commissioned by the Federal Government. Issues discussed include: what is food irradiation; why irradiate food; how much food is consumer rights; and national regulations

  14. ANALISIS KEMAMPUAN KEUANGAN DAERAH PEMERINTAH PROPINSI NUSA TENGGARA BARAT

    Directory of Open Access Journals (Sweden)

    Hery Susanto

    2015-04-01

    Full Text Available This research aims to analyze the regional finance capability in West Nusa Tenggara province. This research uses secondary data of primary source. The data are obtained from the government of West Nusa Tenggara Province in the form of data that has been processed and published and become a legitimate document such as calculation data of APBD in Budgetary Year of 2003-2007. The instruments are used in collecting the data is the analysis of the regional finance capability through Calculation and Work Analysis of PAD, which is the measurement of share and growth, thus classified the result with mapping the financial region capability based on quadrant method. This research draws some conclusions namely: (1 generally, contribution of PAD (share to the total region income of NTB Province TA 2003- 2007 was low, in spite of the growth of PAD was high; (2 based on the measurement of Index Financial Capability (IKK, NTB Province was in the scale index of 0,541. Furthermore, the classification based on the criteria level of regional finance capability, the regional finance capability in NTB Province in 2003 -2007 was a province with high financial capability. There are some suggestions that could be offered to the Government of NTB Province; first, improving PAD share in NTB Province through the excavation of PAD potential sources. Second, concerning with the region cost efficiency, considering that the proportion of PAD achievement was fairly small comparing to the allocation of Region Cost. Penelitian ini bertujuan untuk menganalisis kemampuan keuangan daerah di Propinsi Nusa Tenggara Barat . Penelitian ini menggunakan data sekunder dari sumber utama. Data diperoleh dari pemerintah Propinsi Nusa Tenggara dalam bentuk data yang telah diolah dan dipublikasikan dan menjadi dokumen yang sah seperti data perhitungan APBD Tahun Anggaran 2003-2007. Instrumen yang digunakan dalam pengumpulan data adalah analisis kemampuan keuangan daerah melalui Perhitungan dan

  15. ANALISIS PERILAKU SEKSUAL BERISIKO PADA REMAJA TERINFEKSI HIV DAN AIDS

    Directory of Open Access Journals (Sweden)

    Afritayeni Afritayeni

    2018-03-01

    penelitian eksplanatory research dengan pendekatan kuantitatif.Penelitian ini dilaksanakan dari bulan April-Oktober 2017.Jumlah sampel dalam penelitian ini adalah sebanyak 95 orang remaja yang terinfeksi HIV/ AIDS di Yayasan Sebaya Lancang Kuning dengan teknik pengambilan sampel accidental sampling. Pengumpulan data dilakukan dengan menggunakan data primer dan sekunder. Analisis data menggunakan analisis multivariat dengan uji regresi logistik berganda. Berdasarkan hasil penelitian dapat disimpulkan bahwa faktor yang paling dominan mempengaruhi perilaku seksual remaja adalah dorongan seksual.

  16. Environmental analysis applied to schools. Methodologies for data acquisition; Analisi ambientale iniziale per gli istituti d'istruzione. Metodologia per l'acquisizione dei dati

    Energy Technology Data Exchange (ETDEWEB)

    Andriola, L; Ceccacci, R [ENEA, Div. Caratterizzazione dell' Ambiente e del Territorio, Centro Ricerche Casaccia, Rome (Italy)

    2001-07-01

    The environment analysis is the basis of environmental management for organizations and it is considered as the first step in EMAS. It allows to identify, deal with the issues and have a clear knowledge on environmental performances of organizations. Schools can be included in the organizations. Nevertheless, the complexity of environmental issues and applicable regulations makes very difficult for a school, that wants to implement an environmental management system (EMAS, ISO 14001, etc.), to face this first step. So, it has been defined an instrument, that is easy but complete and coherent with reference standard, to let schools choose their process for elaborating the initial environmental revue. This instrument consists, essentially, in cards that, if completed, facilitate the drafting of the environmental analysis report. [Italian] L'analisi ambientale iniziale costituisce il presupposto di qualsiasi azione di gestione ambientale da parte di un'organizzazione ed e' esplicitamente prevista, come prima tappa, in EMAS. Essa consente infatti di individuare ed approfondire le problematiche ambientali e di fotografare, per mezzo di riferimenti oggettivi, le prestazioni ambientali di un'organizzazione, e quindi anche di una scuola, in modo da poter stabilire e controllare nel tempo gli obiettivi di miglioramento. Tuttavia la complessita' delle problematiche ambientali e delle relative normative di riferimento rende estremamente difficoltoso, per un istituto scolastico che intenda intraprendere un percorso di gestione ambientale comunque finalizzato (EMAS, ISO 14001, Comunicazione ambientale, ecc.) compiere questo passo iniziale. E' stato pertanto realizzato uno strumento semplificato, ma comunque completo e coerente con gli standard di riferimento, per consentire alle scuole di effettuare il percorso di elaborazione di un'analisi ambientale iniziale. Lo strumento consiste essenzialmente in schede che, una volta compilate, faciliteranno la stesura del rapporto di

  17. Evaluation of irradiation hardening of proton irradiated stainless steels by nanoindentation

    International Nuclear Information System (INIS)

    Yabuuchi, Kiyohiro; Kuribayashi, Yutaka; Nogami, Shuhei; Kasada, Ryuta; Hasegawa, Akira

    2014-01-01

    Ion irradiation experiments are useful for investigating irradiation damage. However, estimating the irradiation hardening of ion-irradiated materials is challenging because of the shallow damage induced region. Therefore, the purpose of this study is to prove usefulness of nanoindentation technique for estimation of irradiation hardening for ion-irradiated materials. SUS316L austenitic stainless steel was used and it was irradiated by 1 MeV H + ions to a nominal displacement damage of 0.1, 0.3, 1, and 8 dpa at 573 K. The irradiation hardness of the irradiated specimens were measured and analyzed by Nix–Gao model. The indentation size effect was observed in both unirradiated and irradiated specimens. The hardness of the irradiated specimens changed significantly at certain indentation depths. The depth at which the hardness varied indicated that the region deformed by the indenter had reached the boundary between the irradiated and unirradiated regions. The hardness of the irradiated region was proportional to the inverse of the indentation depth in the Nix–Gao plot. The bulk hardness of the irradiated region, H 0 , estimated by the Nix–Gao plot and Vickers hardness were found to be related to each other, and the relationship could be described by the equation, HV = 0.76H 0 . Thus, the nanoindentation technique demonstrated in this study is valuable for measuring irradiation hardening in ion-irradiated materials

  18. ANALISIS PENGARUH LEVERAGE, PROFITABILITY, DAN FOREIGN OWNERSHIP TERHADAP PENGUNGKAPAN INFORMASI TANGGUNG JAWAB SOSIAL PERUSAHAAN (CORPORATE SOCIAL RESPONSIBILITY

    Directory of Open Access Journals (Sweden)

    Sigit Handoyo

    2017-11-01

    Full Text Available Corporate Social Responsibility is defined as the voluntary activities undertaken by a company to operate in economic, social and environmentally sustainable manner. It's based on Pasal 74 Undang-Undang Perseroan Terbatas No. 40 Tahun 2007. The research aimed to analyze the factors influencing disclosure level of corporate social responsibility at mining sector that listed at Indonesian Stock Exchange (IDX period 2013-2014. In this research caracteristics of the company are consisting of leverage, profitability, and foreign ownership. The population taken in this research was all companies at mining sector that listed in IDX from 2013 to 2014. The method of data analisys was linear regression analisys with SPSS 20. Multiple linear regression analysis technique that used in this research to determine the effect of leverage, profitability and foreign ownership to Corporate Social Responsibility disclosure. Index of corporate social responsibility (CSR is measured with company's indicators disclosed by the number of indicator is set on G4 by Global Reporting Initiative (GRI. Leverage is defined by debt to asset ratio (DAR, profitability is defined by return on assets (ROA, and foreign ownership is defined by the amount of foreign ownership divided by number of outstanding shares. The result of this research showed that leverage and profitability have a positive and significant effect on the CSR disclosure, while the foreign ownership have no effect on CSR disclosure at the mining companies in Indonesia.

  19. Post irradiation test report of irradiated DUPIC simulated fuel

    International Nuclear Information System (INIS)

    Yang, Myung Seung; Jung, I. H.; Moon, J. S. and others

    2001-12-01

    The post-irradiation examination of irradiated DUPIC (Direct Use of Spent PWR Fuel in CANDU Reactors) simulated fuel in HANARO was performed at IMEF (Irradiated Material Examination Facility) in KAERI during 6 months from October 1999 to March 2000. The objectives of this post-irradiation test are i) the integrity of the capsule to be used for DUPIC fuel, ii) ensuring the irradiation requirements of DUPIC fuel at HANARO, iii) performance verification in-core behavior at HANARO of DUPIC simulated fuel, iv) establishing and improvement the data base for DUPIC fuel performance verification codes, and v) establishing the irradiation procedure in HANARO for DUPIC fuel. The post-irradiation examination performed are γ-scanning, profilometry, density, hardness, observation the microstructure and fission product distribution by optical microscope and electron probe microanalyser (EPMA)

  20. Facts about food irradiation: Irradiated foods and the consumer

    International Nuclear Information System (INIS)

    1991-01-01

    This fact sheet discusses market testing of irradiate food, consumer response to irradiated products has always been positive, and in some countries commercial quantities of some irradiated food items have been sold on a regular basis. Consumers have shown no reluctance to buy irradiated food products. 4 refs