WorldWideScience

Sample records for involving large amounts

  1. Another way of managing large amounts of data

    CERN Multimedia

    2009-01-01

    Jeff Hammerbacher is Vice President of Products and Chief Scientist at Cloudera, a US software company that provides solutions for managing and analysing very large data sets. His invited talk on 21 August was a good opportunity to exchange views with the CERN experts who face similar problems. Although still relatively young, Jeff has considerable experience in developing tools for storing and processing large amounts of data. Before Cloudera Jeff conceived, built and led the Data team at Facebook. He has also worked as a quantitative analyst on Wall Street. Jeff holds a Bachelor’s Degree in mathematics from Harvard University. At CERN, handling large amounts of data is the job of the Grid; Hadoop, the software Cloudera is developing, is intended for the same scope but has different technical features and implementations. "The Grid software products are designed for many organisations to collaborate on large-scale data analysis across many data centres. In contrast, Had...

  2. Discovering Related Clinical Concepts Using Large Amounts of Clinical Notes.

    Science.gov (United States)

    Ganesan, Kavita; Lloyd, Shane; Sarkar, Vikren

    2016-01-01

    The ability to find highly related clinical concepts is essential for many applications such as for hypothesis generation, query expansion for medical literature search, search results filtering, ICD-10 code filtering and many other applications. While manually constructed medical terminologies such as SNOMED CT can surface certain related concepts, these terminologies are inadequate as they depend on expertise of several subject matter experts making the terminology curation process open to geographic and language bias. In addition, these terminologies also provide no quantifiable evidence on how related the concepts are. In this work, we explore an unsupervised graphical approach to mine related concepts by leveraging the volume within large amounts of clinical notes. Our evaluation shows that we are able to use a data driven approach to discovering highly related concepts for various search terms including medications, symptoms and diseases.

  3. Discovering Related Clinical Concepts Using Large Amounts of Clinical Notes

    Directory of Open Access Journals (Sweden)

    Kavita Ganesan

    2016-01-01

    Full Text Available The ability to find highly related clinical concepts is essential for many applications such as for hypothesis generation, query expansion for medical literature search, search results filtering, ICD-10 code filtering and many other applications. While manually constructed medical terminologies such as SNOMED CT can surface certain related concepts, these terminologies are inadequate as they depend on expertise of several subject matter experts making the terminology curation process open to geographic and language bias. In addition, these terminologies also provide no quantifiable evidence on how related the concepts are. In this work, we explore an unsupervised graphical approach to mine related concepts by leveraging the volume within large amounts of clinical notes. Our evaluation shows that we are able to use a data driven approach to discovering highly related concepts for various search terms including medications, symptoms and diseases.

  4. Knowledge discovery: Extracting usable information from large amounts of data

    International Nuclear Information System (INIS)

    Whiteson, R.

    1998-01-01

    The threat of nuclear weapons proliferation is a problem of world wide concern. Safeguards are the key to nuclear nonproliferation and data is the key to safeguards. The safeguards community has access to a huge and steadily growing volume of data. The advantages of this data rich environment are obvious, there is a great deal of information which can be utilized. The challenge is to effectively apply proven and developing technologies to find and extract usable information from that data. That information must then be assessed and evaluated to produce the knowledge needed for crucial decision making. Efficient and effective analysis of safeguards data will depend on utilizing technologies to interpret the large, heterogeneous data sets that are available from diverse sources. With an order-of-magnitude increase in the amount of data from a wide variety of technical, textual, and historical sources there is a vital need to apply advanced computer technologies to support all-source analysis. There are techniques of data warehousing, data mining, and data analysis that can provide analysts with tools that will expedite their extracting useable information from the huge amounts of data to which they have access. Computerized tools can aid analysts by integrating heterogeneous data, evaluating diverse data streams, automating retrieval of database information, prioritizing inputs, reconciling conflicting data, doing preliminary interpretations, discovering patterns or trends in data, and automating some of the simpler prescreening tasks that are time consuming and tedious. Thus knowledge discovery technologies can provide a foundation of support for the analyst. Rather than spending time sifting through often irrelevant information, analysts could use their specialized skills in a focused, productive fashion. This would allow them to make their analytical judgments with more confidence and spend more of their time doing what they do best

  5. Large amounts of antiproton production by heavy ion collision

    International Nuclear Information System (INIS)

    Takahashi, Hiroshi; Powell, J.

    1987-01-01

    To produce large amounts of antiprotons, on the order of several grams/year, use of machines to produce nuclear collisions are studied. These can be of either proton-proton, proton-nucleus and nucleus-nucleus in nature. To achieve high luminosity colliding beams, on the order of 10 41 m/cm 2 , a self-colliding machine is required, rather than a conventional circular colliding type. The self-colliding machine can produce additional antiprotons through successive collisions of secondary particles, such as spectator nucleons. A key problem is how to collect the produced antiprotons without capture by beam nuclei in the collision zone. Production costs for anti-matter are projected for various energy source options and technology levels. Dedicated facilities using heavy ion collisions could produce antiproton at substantially less than 1 million $/milligram. With co-production of other valuable products, e.g., nuclear fuel for power reactors, antiproton costs could be reduced to even lower values

  6. Large amounts of antiproton production by heavy ion collision

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, Hiroshi; Powell, J.

    1987-01-01

    To produce large amounts of antiprotons, on the order of several grams/year, use of machines to produce nuclear collisions are studied. These can be of either proton-proton, proton-nucleus and nucleus-nucleus in nature. To achieve high luminosity colliding beams, on the order of 10/sup 41/ m/cm/sup 2/, a self-colliding machine is required, rather than a conventional circular colliding type. The self-colliding machine can produce additional antiprotons through successive collisions of secondary particles, such as spectator nucleons. A key problem is how to collect the produced antiprotons without capture by beam nuclei in the collision zone. Production costs for anti-matter are projected for various energy source options and technology levels. Dedicated facilities using heavy ion collisions could produce antiproton at substantially less than 1 million $/milligram. With co-production of other valuable products, e.g., nuclear fuel for power reactors, antiproton costs could be reduced to even lower values.

  7. Expert system shell to reason on large amounts of data

    Science.gov (United States)

    Giuffrida, Gionanni

    1994-01-01

    The current data base management systems (DBMS's) do not provide a sophisticated environment to develop rule based expert systems applications. Some of the new DBMS's come with some sort of rule mechanism; these are active and deductive database systems. However, both of these are not featured enough to support full implementation based on rules. On the other hand, current expert system shells do not provide any link with external databases. That is, all the data are kept in the system working memory. Such working memory is maintained in main memory. For some applications the reduced size of the available working memory could represent a constraint for the development. Typically these are applications which require reasoning on huge amounts of data. All these data do not fit into the computer main memory. Moreover, in some cases these data can be already available in some database systems and continuously updated while the expert system is running. This paper proposes an architecture which employs knowledge discovering techniques to reduce the amount of data to be stored in the main memory; in this architecture a standard DBMS is coupled with a rule-based language. The data are stored into the DBMS. An interface between the two systems is responsible for inducing knowledge from the set of relations. Such induced knowledge is then transferred to the rule-based language working memory.

  8. Comparison Analysis among Large Amount of SNS Sites

    Science.gov (United States)

    Toriumi, Fujio; Yamamoto, Hitoshi; Suwa, Hirohiko; Okada, Isamu; Izumi, Kiyoshi; Hashimoto, Yasuhiro

    In recent years, application of Social Networking Services (SNS) and Blogs are growing as new communication tools on the Internet. Several large-scale SNS sites are prospering; meanwhile, many sites with relatively small scale are offering services. Such small-scale SNSs realize small-group isolated type of communication while neither mixi nor MySpace can do that. However, the studies on SNS are almost about particular large-scale SNSs and cannot analyze whether their results apply for general features or for special characteristics on the SNSs. From the point of view of comparison analysis on SNS, comparison with just several types of those cannot reach a statistically significant level. We analyze many SNS sites with the aim of classifying them by using some approaches. Our paper classifies 50,000 sites for small-scale SNSs and gives their features from the points of network structure, patterns of communication, and growth rate of SNS. The result of analysis for network structure shows that many SNS sites have small-world attribute with short path lengths and high coefficients of their cluster. Distribution of degrees of the SNS sites is close to power law. This result indicates the small-scale SNS sites raise the percentage of users with many friends than mixi. According to the analysis of their coefficients of assortativity, those SNS sites have negative values of assortativity, and that means users with high degree tend to connect users with small degree. Next, we analyze the patterns of user communication. A friend network of SNS is explicit while users' communication behaviors are defined as an implicit network. What kind of relationships do these networks have? To address this question, we obtain some characteristics of users' communication structure and activation patterns of users on the SNS sites. By using new indexes, friend aggregation rate and friend coverage rate, we show that SNS sites with high value of friend coverage rate activate diary postings

  9. Elephant’s breast milk contains large amounts of glucosamine

    Science.gov (United States)

    TAKATSU, Zenta; TSUDA, Muneya; YAMADA, Akio; MATSUMOTO, Hiroshi; TAKAI, Akira; TAKEDA, Yasuhiro; TAKASE, Mitsunori

    2016-01-01

    Hand-reared elephant calves that are nursed with milk substitutes sometimes suffer bone fractures, probably due to problems associated with nutrition, exercise, sunshine levels and/or genetic factors. As we were expecting the birth of an Asian elephant (Elephas maximus), we analyzed elephant’s breast milk to improve the milk substitutes for elephant calves. Although there were few nutritional differences between conventional substitutes and elephant’s breast milk, we found a large unknown peak in the breast milk during high-performance liquid chromatography-based amino acid analysis and determined that it was glucosamine (GlcN) using liquid chromatography/mass spectrometry. We detected the following GlcN concentrations [mean ± SD] (mg/100 g) in milk hydrolysates produced by treating samples with 6M HCl for 24 hr at 110°C: four elephant’s breast milk samples: 516 ± 42, three cow’s milk mixtures: 4.0 ± 2.2, three mare’s milk samples: 12 ± 1.2 and two human milk samples: 38. The GlcN content of the elephant’s milk was 128, 43 and 14 times greater than those of the cow’s, mare’s and human milk, respectively. Then, we examined the degradation of GlcN during 0–24 hr hydrolyzation with HCl. We estimated that elephant’s milk contains >880 mg/100 g GlcN, which is similar to the levels of major amino acids in elephant’s milk. We concluded that a novel GlcN-containing milk substitute should be developed for elephant calves. The efficacy of GlcN supplements is disputed, and free GlcN is rare in bodily fluids; thus, the optimal molecular form of GlcN requires a further study. PMID:28049867

  10. Severities of transportation accidents involving large packages

    Energy Technology Data Exchange (ETDEWEB)

    Dennis, A.W.; Foley, J.T. Jr.; Hartman, W.F.; Larson, D.W.

    1978-05-01

    The study was undertaken to define in a quantitative nonjudgmental technical manner the abnormal environments to which a large package (total weight over 2 tons) would be subjected as the result of a transportation accident. Because of this package weight, air shipment was not considered as a normal transportation mode and was not included in the study. The abnormal transportation environments for shipment by motor carrier and train were determined and quantified. In all cases the package was assumed to be transported on an open flat-bed truck or an open flat-bed railcar. In an earlier study, SLA-74-0001, the small-package environments were investigated. A third transportation study, related to the abnormal environment involving waterways transportation, is now under way at Sandia Laboratories and should complete the description of abnormal transportation environments. Five abnormal environments were defined and investigated, i.e., fire, impact, crush, immersion, and puncture. The primary interest of the study was directed toward the type of large package used to transport radioactive materials; however, the findings are not limited to this type of package but can be applied to a much larger class of material shipping containers.

  11. Severities of transportation accidents involving large packages

    International Nuclear Information System (INIS)

    Dennis, A.W.; Foley, J.T. Jr.; Hartman, W.F.; Larson, D.W.

    1978-05-01

    The study was undertaken to define in a quantitative nonjudgmental technical manner the abnormal environments to which a large package (total weight over 2 tons) would be subjected as the result of a transportation accident. Because of this package weight, air shipment was not considered as a normal transportation mode and was not included in the study. The abnormal transportation environments for shipment by motor carrier and train were determined and quantified. In all cases the package was assumed to be transported on an open flat-bed truck or an open flat-bed railcar. In an earlier study, SLA-74-0001, the small-package environments were investigated. A third transportation study, related to the abnormal environment involving waterways transportation, is now under way at Sandia Laboratories and should complete the description of abnormal transportation environments. Five abnormal environments were defined and investigated, i.e., fire, impact, crush, immersion, and puncture. The primary interest of the study was directed toward the type of large package used to transport radioactive materials; however, the findings are not limited to this type of package but can be applied to a much larger class of material shipping containers

  12. Generation Expansion Planning With Large Amounts of Wind Power via Decision-Dependent Stochastic Programming

    Energy Technology Data Exchange (ETDEWEB)

    Zhan, Yiduo; Zheng, Qipeng P.; Wang, Jianhui; Pinson, Pierre

    2017-07-01

    Power generation expansion planning needs to deal with future uncertainties carefully, given that the invested generation assets will be in operation for a long time. Many stochastic programming models have been proposed to tackle this challenge. However, most previous works assume predetermined future uncertainties (i.e., fixed random outcomes with given probabilities). In several recent studies of generation assets' planning (e.g., thermal versus renewable), new findings show that the investment decisions could affect the future uncertainties as well. To this end, this paper proposes a multistage decision-dependent stochastic optimization model for long-term large-scale generation expansion planning, where large amounts of wind power are involved. In the decision-dependent model, the future uncertainties are not only affecting but also affected by the current decisions. In particular, the probability distribution function is determined by not only input parameters but also decision variables. To deal with the nonlinear constraints in our model, a quasi-exact solution approach is then introduced to reformulate the multistage stochastic investment model to a mixed-integer linear programming model. The wind penetration, investment decisions, and the optimality of the decision-dependent model are evaluated in a series of multistage case studies. The results show that the proposed decision-dependent model provides effective optimization solutions for long-term generation expansion planning.

  13. A simple biosynthetic pathway for large product generation from small substrate amounts

    Science.gov (United States)

    Djordjevic, Marko; Djordjevic, Magdalena

    2012-10-01

    A recently emerging discipline of synthetic biology has the aim of constructing new biosynthetic pathways with useful biological functions. A major application of these pathways is generating a large amount of the desired product. However, toxicity due to the possible presence of toxic precursors is one of the main problems for such production. We consider here the problem of generating a large amount of product from a potentially toxic substrate. To address this, we propose a simple biosynthetic pathway, which can be induced in order to produce a large number of the product molecules, by keeping the substrate amount at low levels. Surprisingly, we show that the large product generation crucially depends on fast non-specific degradation of the substrate molecules. We derive an optimal induction strategy, which allows as much as three orders of magnitude increase in the product amount through biologically realistic parameter values. We point to a recently discovered bacterial immune system (CRISPR/Cas in E. coli) as a putative example of the pathway analysed here. We also argue that the scheme proposed here can be used not only as a stand-alone pathway, but also as a strategy to produce a large amount of the desired molecules with small perturbations of endogenous biosynthetic pathways.

  14. A simple biosynthetic pathway for large product generation from small substrate amounts

    Energy Technology Data Exchange (ETDEWEB)

    Djordjevic, Marko [Institute of Physiology and Biochemistry, Faculty of Biology, University of Belgrade (Serbia); Djordjevic, Magdalena [Institute of Physics Belgrade, University of Belgrade (Serbia)

    2012-10-01

    A recently emerging discipline of synthetic biology has the aim of constructing new biosynthetic pathways with useful biological functions. A major application of these pathways is generating a large amount of the desired product. However, toxicity due to the possible presence of toxic precursors is one of the main problems for such production. We consider here the problem of generating a large amount of product from a potentially toxic substrate. To address this, we propose a simple biosynthetic pathway, which can be induced in order to produce a large number of the product molecules, by keeping the substrate amount at low levels. Surprisingly, we show that the large product generation crucially depends on fast non-specific degradation of the substrate molecules. We derive an optimal induction strategy, which allows as much as three orders of magnitude increase in the product amount through biologically realistic parameter values. We point to a recently discovered bacterial immune system (CRISPR/Cas in E. coli) as a putative example of the pathway analysed here. We also argue that the scheme proposed here can be used not only as a stand-alone pathway, but also as a strategy to produce a large amount of the desired molecules with small perturbations of endogenous biosynthetic pathways. (paper)

  15. A simple biosynthetic pathway for large product generation from small substrate amounts

    International Nuclear Information System (INIS)

    Djordjevic, Marko; Djordjevic, Magdalena

    2012-01-01

    A recently emerging discipline of synthetic biology has the aim of constructing new biosynthetic pathways with useful biological functions. A major application of these pathways is generating a large amount of the desired product. However, toxicity due to the possible presence of toxic precursors is one of the main problems for such production. We consider here the problem of generating a large amount of product from a potentially toxic substrate. To address this, we propose a simple biosynthetic pathway, which can be induced in order to produce a large number of the product molecules, by keeping the substrate amount at low levels. Surprisingly, we show that the large product generation crucially depends on fast non-specific degradation of the substrate molecules. We derive an optimal induction strategy, which allows as much as three orders of magnitude increase in the product amount through biologically realistic parameter values. We point to a recently discovered bacterial immune system (CRISPR/Cas in E. coli) as a putative example of the pathway analysed here. We also argue that the scheme proposed here can be used not only as a stand-alone pathway, but also as a strategy to produce a large amount of the desired molecules with small perturbations of endogenous biosynthetic pathways. (paper)

  16. Detection of tiny amounts of fissile materials in large-sized containers with radioactive waste

    Science.gov (United States)

    Batyaev, V. F.; Skliarov, S. V.

    2018-01-01

    The paper is devoted to non-destructive control of tiny amounts of fissile materials in large-sized containers filled with radioactive waste (RAW). The aim of this work is to model an active neutron interrogation facility for detection of fissile ma-terials inside NZK type containers with RAW and determine the minimal detectable mass of U-235 as a function of various param-eters: matrix type, nonuniformity of container filling, neutron gen-erator parameters (flux, pulse frequency, pulse duration), meas-urement time. As a result the dependence of minimal detectable mass on fissile materials location inside container is shown. Nonu-niformity of the thermal neutron flux inside a container is the main reason of the space-heterogeneity of minimal detectable mass in-side a large-sized container. Our experiments with tiny amounts of uranium-235 (<1 g) confirm the detection of fissile materials in NZK containers by using active neutron interrogation technique.

  17. Detection of tiny amounts of fissile materials in large-sized containers with radioactive waste

    Directory of Open Access Journals (Sweden)

    Batyaev V.F.

    2018-01-01

    Full Text Available The paper is devoted to non-destructive control of tiny amounts of fissile materials in large-sized containers filled with radioactive waste (RAW. The aim of this work is to model an active neutron interrogation facility for detection of fissile ma-terials inside NZK type containers with RAW and determine the minimal detectable mass of U-235 as a function of various param-eters: matrix type, nonuniformity of container filling, neutron gen-erator parameters (flux, pulse frequency, pulse duration, meas-urement time. As a result the dependence of minimal detectable mass on fissile materials location inside container is shown. Nonu-niformity of the thermal neutron flux inside a container is the main reason of the space-heterogeneity of minimal detectable mass in-side a large-sized container. Our experiments with tiny amounts of uranium-235 (<1 g confirm the detection of fissile materials in NZK containers by using active neutron interrogation technique.

  18. Alternative containers for low-level wastes containing large amounts of tritium

    International Nuclear Information System (INIS)

    Gause, E.P.; Lee, B.S.; MacKenzie, D.R.; Wiswall, R. Jr.

    1984-11-01

    High-activity tritiated waste generated in the United States is mainly composed of tritium gas and tritium-contaminated organic solvents sorbed onto Speedi-Dri which are packaged in small glass bulbs. Low-activity waste consists of solidified and adsorbed liquids. In this report, current packages for high-activity gaseous and low-activity adsorbed liquid wastes are emphasized with regard to containment potential. Containers for low-level radioactive waste containing large amounts of tritium need to be developed. An integrity may be threatened by: physical degradation due to soil corrosion, gas pressure build-up (due to radiolysis and/or biodegradation), rapid permeation of tritium through the container, and corrosion from container contents. Literature available on these points is summarized in this report. 136 references, 20 figures, 40 tables

  19. Transient Stability Assessment of Power System with Large Amount of Wind Power Penetration

    DEFF Research Database (Denmark)

    Liu, Leo; Chen, Zhe; Bak, Claus Leth

    2012-01-01

    Recently, the security and stability of power system with large amount of wind power are the concerned issues, especially the transient stability. In Denmark, the onshore and offshore wind farms are connected to distribution system and transmission system respectively. The control and protection...... methodologies of onshore and offshore wind farms definitely affect the transient stability of power system. In this paper, the onshore and offshore wind farms are modeled in detail in order to assess the transient stability of western Danish power system. Further, the computation of critical clearing time (CCT...... plants, load consumption level and high voltage direct current (HVDC) transmission links are taken into account. The results presented in this paper are able to provide an early awareness of power system security condition of the western Danish power system....

  20. Integration of large amounts of wind power. Markets for trading imbalances

    Energy Technology Data Exchange (ETDEWEB)

    Neimane, Viktoria; Axelsson, Urban [Vattenfall Research and Development AB, Stockholm (Sweden); Gustafsson, Johan; Gustafsson, Kristian [Vattenfall Nordic Generation Management, Stockholm (Sweden); Murray, Robin [Vattenfall Vindkraft AB, Stockholm (Sweden)

    2008-07-01

    The well-known concerns about wind power are related to its intermittent nature and difficulty to make exact forecasts. The expected increase in balancing and reserve requirements due to wind power has been investigated in several studies. This paper takes the next step in studying integration of large amounts of wind power in Sweden. Several wind power producers' and corresponding balance providers' perspective is taken and their imbalance costs modeled. Larger producers having wind power spread over larger geographical areas will have lower relative costs than producers having their units concentrated within limited geographical area. Possibilities of the wind power producers to reduce the imbalance costs by acting on after sales market are exposed and compared. (orig.)

  1. Imbalance costs in the Swedish system with large amounts of wind power

    Energy Technology Data Exchange (ETDEWEB)

    Carlsson, Fredrik; Neimane, Viktoria [Vattenfall Research and Development AB, Stockholm (Sweden)

    2009-07-01

    The well-known concerns about wind power are related to its intermittent nature and difficulty to make exact forecasts. The expected increase in balancing and reserve requirements due to wind power has been investigated in several studies. This paper takes the next step in studying integration of large amounts of wind power in Sweden. Several wind power producers' and corresponding balance providers' perspective is taken and their imbalance costs modeled. Larger producers having wind power spread over larger geographical areas will have lower relative costs than producers having their units concentrated within limited geographical area. Possibilities of the wind power producers to reduce the imbalance costs by acting on after sales market are exposed and compared. (orig.)

  2. Analytics to Better Interpret and Use Large Amounts of Heterogeneous Data

    Science.gov (United States)

    Mathews, T. J.; Baskin, W. E.; Rinsland, P. L.

    2014-12-01

    Data scientists at NASA's Atmospheric Science Data Center (ASDC) are seasoned software application developers who have worked with the creation, archival, and distribution of large datasets (multiple terabytes and larger). In order for ASDC data scientists to effectively implement the most efficient processes for cataloging and organizing data access applications, they must be intimately familiar with data contained in the datasets with which they are working. Key technologies that are critical components to the background of ASDC data scientists include: large RBMSs (relational database management systems) and NoSQL databases; web services; service-oriented architectures; structured and unstructured data access; as well as processing algorithms. However, as prices of data storage and processing decrease, sources of data increase, and technologies advance - granting more people to access to data at real or near-real time - data scientists are being pressured to accelerate their ability to identify and analyze vast amounts of data. With existing tools this is becoming exceedingly more challenging to accomplish. For example, NASA Earth Science Data and Information System (ESDIS) alone grew from having just over 4PBs of data in 2009 to nearly 6PBs of data in 2011. This amount then increased to roughly10PBs of data in 2013. With data from at least ten new missions to be added to the ESDIS holdings by 2017, the current volume will continue to grow exponentially and drive the need to be able to analyze more data even faster. Though there are many highly efficient, off-the-shelf analytics tools available, these tools mainly cater towards business data, which is predominantly unstructured. Inadvertently, there are very few known analytics tools that interface well to archived Earth science data, which is predominantly heterogeneous and structured. This presentation will identify use cases for data analytics from an Earth science perspective in order to begin to identify

  3. Fatal crashes involving large numbers of vehicles and weather.

    Science.gov (United States)

    Wang, Ying; Liang, Liming; Evans, Leonard

    2017-12-01

    Adverse weather has been recognized as a significant threat to traffic safety. However, relationships between fatal crashes involving large numbers of vehicles and weather are rarely studied according to the low occurrence of crashes involving large numbers of vehicles. By using all 1,513,792 fatal crashes in the Fatality Analysis Reporting System (FARS) data, 1975-2014, we successfully described these relationships. We found: (a) fatal crashes involving more than 35 vehicles are most likely to occur in snow or fog; (b) fatal crashes in rain are three times as likely to involve 10 or more vehicles as fatal crashes in good weather; (c) fatal crashes in snow [or fog] are 24 times [35 times] as likely to involve 10 or more vehicles as fatal crashes in good weather. If the example had used 20 vehicles, the risk ratios would be 6 for rain, 158 for snow, and 171 for fog. To reduce the risk of involvement in fatal crashes with large numbers of vehicles, drivers should slow down more than they currently do under adverse weather conditions. Driver deaths per fatal crash increase slowly with increasing numbers of involved vehicles when it is snowing or raining, but more steeply when clear or foggy. We conclude that in order to reduce risk of involvement in crashes involving large numbers of vehicles, drivers must reduce speed in fog, and in snow or rain, reduce speed by even more than they already do. Copyright © 2017 National Safety Council and Elsevier Ltd. All rights reserved.

  4. Consumers' Reaction towards Involvement of Large Retailers in ...

    African Journals Online (AJOL)

    User

    markets, fair trade products need LRs distribution channels and not the old system of using speciality ... analysis employed to identify customers' reaction to large retailers' involvement in selling ...... The Journal of Socio-Economics. Vol. 37: pp.

  5. Very large amounts of radiation are needed to change cancer frequency

    International Nuclear Information System (INIS)

    Brooks, A.; Couch, L.

    2006-01-01

    Full text: A marked radio-phobia or excessive fear of radiation exposure is shared by the general public. A major factor in this fear is that the perception that each and every radiation-induced ionization increases the risk for cancer, thus even the smallest radiation exposure needs to be avoided. It is important to realize that this is not the case. It requires very large amounts of radiation delivered to large populations to produce an increase in cancer frequency. This has been demonstrated in many in experimental systems, animal studies and in human populations. If either the population size or the dose is reduced it is not possible to detect an increase in cancer frequency. This paper deals with real radiation-induced increases in cancer frequency that are statistically significant, rather than in extrapolated or calculated small increases in radiation-induced risks using linear models. Further, it demonstrates that there are barriers below which increases in cancer cannot be detected. Finally, the manuscript helps explain that there are transitions in the mechanisms of biological action as a function of radiation dose with very different mechanisms being triggered at high and at low doses. These transitions suggest the need for paradigm shifts. Concepts such as hit theory, independence in individual cellular responses and single mutations being responsible for cancer need to be re-evaluated. New paradigms such as b ystander effects , showing that the size of the responding target is much larger than the hit target, adaptive response demonstrating that cell/cell communication modifies individual cellular responses and genomic instability that is not dependent on radiation induced mutations in individual cells

  6. Environmental contamination due to release of a large amount of tritium

    International Nuclear Information System (INIS)

    Kawai, Hiroshi

    1988-01-01

    Tritium release incidents have occurred many times in the Savannah Rever Plant in the U.S. A tritium release incident also took place in the Lawrence Livermore Laboratory. The present article outlines the reports by the plant and laboratory on these incidents and makes some comments on environmental contamination that may results from release of a large amount of tritium from nuclear fusion facilities. Tritium is normally released in the form of a combination of chemical compounds such as HT, DT and T 2 and oxides such as HTO, DTO and T 2 O. The percentage of the oxides is given in the reports by the plant. Oxides, which can be absorbed through the skin, are considered to be nearly a thousand times more toxic than the other type of tritium compounds. The HT type compounds (HT, DT and T 2 ) can be oxidized by microorganisms in soil into oxides (HTO, DTO and T 2 O) and therefore, great care should also given to this type of compounds. After each accidental tritium release, the health physics group of the plant collected various environmental samples, including ground surface water, milk, leaves of plants, soil and human urine, in leeward areas. Results on the contamination of surface water, fish and underground water are outlined and discussed. (Nogami, K.)

  7. Biological soil crusts emit large amounts of NO and HONO affecting the nitrogen cycle in drylands

    Science.gov (United States)

    Tamm, Alexandra; Wu, Dianming; Ruckteschler, Nina; Rodríguez-Caballero, Emilio; Steinkamp, Jörg; Meusel, Hannah; Elbert, Wolfgang; Behrendt, Thomas; Sörgel, Matthias; Cheng, Yafang; Crutzen, Paul J.; Su, Hang; Pöschl, Ulrich; Weber, Bettina

    2016-04-01

    Dryland systems currently cover ˜40% of the world's land surface and are still expanding as a consequence of human impact and global change. In contrast to that, information on their role in global biochemical processes is limited, probably induced by the presumption that their sparse vegetation cover plays a negligible role in global balances. However, spaces between the sparse shrubs are not bare, but soils are mostly covered by biological soil crusts (biocrusts). These biocrust communities belong to the oldest life forms, resulting from an assembly between soil particles and cyanobacteria, lichens, bryophytes, and algae plus heterotrophic organisms in varying proportions. Depending on the dominating organism group, cyanobacteria-, lichen-, and bryophyte-dominated biocrusts are distinguished. Besides their ability to restrict soil erosion they fix atmospheric carbon and nitrogen, and by doing this they serve as a nutrient source in strongly depleted dryland ecosystems. In this study we show that a fraction of the nitrogen fixed by biocrusts is metabolized and subsequently returned to the atmosphere in the form of nitric oxide (NO) and nitrous acid (HONO). These gases affect the radical formation and oxidizing capacity within the troposphere, thus being of particular interest to atmospheric chemistry. Laboratory measurements using dynamic chamber systems showed that dark cyanobacteria-dominated crusts emitted the largest amounts of NO and HONO, being ˜20 times higher than trace gas fluxes of nearby bare soil. We showed that these nitrogen emissions have a biogenic origin, as emissions of formerly strongly emitting samples almost completely ceased after sterilization. By combining laboratory, field, and satellite measurement data we made a best estimate of global annual emissions amounting to ˜1.1 Tg of NO-N and ˜0.6 Tg of HONO-N from biocrusts. This sum of 1.7 Tg of reactive nitrogen emissions equals ˜20% of the soil release under natural vegetation according

  8. LARGE VESSEL INVOLVEMENT IN BEHCET’S DISEASE

    Directory of Open Access Journals (Sweden)

    AR. Jamshidi F. Davatchi

    2004-08-01

    Full Text Available Large vessel involvement is one of the hallmarks of Behcet’s disease (BD but its prevalence varies widely due to ethnic variation or environmental factors. The aim of this study is to find the characteristics of vasculo-Behcet (VB in Iran. In a cohort of 4769 patients with BD, those with vascular involvement were selected. Different manifestations of disease were compared with the remaining group of patients. A confidence interval at 95% (CI was calculated for each item. Vascular involvement was seen in 409 cases (8.6%; CI, 0.8. Venous involvement was seen in 396 cases, deep vein thrombosis in 294 (6.2%; CI, 0.7, superficial phlebitis in 108 (2.3%; CI, 0.4 and large vein thrombosis in 45 (0.9%; CI, 0.3. Arterial involvement was seen in 28 patients (25 aneurysms and 4 thromboses. Thirteen patients showed both arterial and venous involvement. The mean age of the patients with VB was slightly higher (P<0.03, but the disease duration was significantly longer (P<0.0003. VB was more common in men. As the presenting sign, ocular lesions were less frequent in VB (P<0.0006, while skin lesions were over 2 times more common in these cases (P<0.000001. VB was associated with a higher frequency of genital aphthosis, skin involvement, joint manifestations, epididymitis, CNS lesions and GI involvement. The juvenile form was less common in VB (P<0.03. High ESR was more frequent in VB (P=0.000002, but the frequency of false positive VDRL, pathergy phenomenon, HLA-B5 or HLA-B27 showed no significant difference between the two groups. In Iranian patients with BD, vascular involvement is not common and large vessel involvement is rare. It may be sex-related, and is more common in well-established disease with multiple organ involvement and longer disease duration.

  9. Improved recovery of trace amounts of gold (III), palladium (II) and platinum (IV) from large amounts of associated base metals using anion-exchange resins

    Energy Technology Data Exchange (ETDEWEB)

    Matsubara, I. [Lab. of Chemistry, Tokyo Women' s Medical Univ. (Japan); Takeda, Y.; Ishida, K. [Lab. of Chemistry, Nippon Medical School, Kawasaki-shi, Kanagawa-ken (Japan)

    2000-02-01

    The adsorption and desorption behaviors of gold (III), palladium (II) and platinum (IV) were surveyed in column chromatographic systems consisting of one of the conventional anion-exchange resins of large ion-exchange capacity and dilute thiourea solutions. The noble metals were strongly adsorbed on the anion-exchange resins from dilute hydrochloric acid, while most base metals did not show any marked adsorbability. These facts made it possible to separate the noble metals from a large quantity of base metals such as Ag (I), Al (III), Co (II), Cu (II), Fe (III), Mn (II), Ni (II), Pb (II), and Zn (II). Although it used to be very difficult to desorb the noble metals from the resins used, the difficulty was easily overcome by use of dilute thiourea solutions as an eluant. In the present study, as little as 1.00 {mu}g of the respective noble metals was quantitatively separated and recovered from as much as ca. 10 mg of a number of metals on a small column by elution with a small amount of dilute thiourea solution. The present systems should be applicable to the separation, concentration and recovery of traces of the noble metals from a number of base metals coexisting in a more extended range of amounts and ratios. (orig.)

  10. Large vessel involvement by IgG4-related disease

    Science.gov (United States)

    Perugino, Cory A.; Wallace, Zachary S.; Meyersohn, Nandini; Oliveira, George; Stone, James R.; Stone, John H.

    2016-01-01

    Abstract Objectives: IgG4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory condition that can affect multiple organs and lead to tumefactive, tissue-destructive lesions. Reports have described inflammatory aortitis and periaortitis, the latter in the setting of retroperitoneal fibrosis (RPF), but have not distinguished adequately between these 2 manifestations. The frequency, radiologic features, and response of vascular complications to B cell depletion remain poorly defined. We describe the clinical features, radiology findings, and treatment response in a cohort of 36 patients with IgG4-RD affecting large blood vessels. Methods: Clinical records of all patients diagnosed with IgG4-RD in our center were reviewed. All radiologic studies were reviewed. We distinguished between primary large blood vessel inflammation and secondary vascular involvement. Primary involvement was defined as inflammation in the blood vessel wall as a principal focus of disease. Secondary vascular involvement was defined as disease caused by the effects of adjacent inflammation on the blood vessel wall. Results: Of the 160 IgG4-RD patients in this cohort, 36 (22.5%) had large-vessel involvement. The mean age at disease onset of the patients with large-vessel IgG4-RD was 54.6 years. Twenty-eight patients (78%) were male and 8 (22%) were female. Thirteen patients (36%) had primary IgG4-related vasculitis and aortitis with aneurysm formation comprised the most common manifestation. This affected 5.6% of the entire IgG4-RD cohort and was observed in the thoracic aorta in 8 patients, the abdominal aorta in 4, and both the thoracic and abdominal aorta in 3. Three of these aneurysms were complicated by aortic dissection or contained perforation. Periaortitis secondary to RPF accounted for 27 of 29 patients (93%) of secondary vascular involvement by IgG4-RD. Only 5 patients demonstrated evidence of both primary and secondary blood vessel involvement. Of those treated with

  11. Quantitative analysis of large amounts of journalistic texts using topic modelling

    NARCIS (Netherlands)

    Jacobi, C.; van Atteveldt, W.H.; Welbers, K.

    2016-01-01

    The huge collections of news content which have become available through digital technologies both enable and warrant scientific inquiry, challenging journalism scholars to analyse unprecedented amounts of texts. We propose Latent Dirichlet Allocation (LDA) topic modelling as a tool to face this

  12. Methods to isolate a large amount of generative cells, sperm cells and vegetative nuclei from tomato pollen for omics analysis

    Directory of Open Access Journals (Sweden)

    Yunlong eLu

    2015-06-01

    Full Text Available The development of sperm cells from microspores involves a set of finely regulated molecular and cellular events and the coordination of these events. The mechanisms underlying these events and their interconnections remain a major challenge. Systems analysis of genome-wide molecular networks and functional modules with high-throughput omics approaches is crucial for understanding the mechanisms; however, this study is hindered because of the difficulty in isolating a large amount of cells of different types, especially generative cells (GCs, from the pollen. Here, we optimized the conditions of tomato pollen germination and pollen tube growth to allow for long-term growth of pollen tubes in vitro with sperm cells (SCs generated in the tube. Using this culture system, we developed methods for isolating GCs, SCs and vegetative-cell nuclei (VN from just-germinated tomato pollen grains and growing pollen tubes and their purification by Percoll density gradient centrifugation. The purity and viability of isolated GCs and SCs were confirmed by microscopy examination and fluorescein diacetate staining, respectively, and the integrity of VN was confirmed by propidium iodide staining. We could obtain about 1.5 million GCs and 2.0 million SCs each from 180 mg initiated pollen grains, and 10 million VN from 270 mg initiated pollen grains germinated in vitro in each experiment. These methods provide the necessary preconditions for systematic biology studies of SC development and differentiation in higher plants.

  13. Methods to isolate a large amount of generative cells, sperm cells and vegetative nuclei from tomato pollen for "omics" analysis.

    Science.gov (United States)

    Lu, Yunlong; Wei, Liqin; Wang, Tai

    2015-01-01

    The development of sperm cells (SCs) from microspores involves a set of finely regulated molecular and cellular events and the coordination of these events. The mechanisms underlying these events and their interconnections remain a major challenge. Systems analysis of genome-wide molecular networks and functional modules with high-throughput "omics" approaches is crucial for understanding the mechanisms; however, this study is hindered because of the difficulty in isolating a large amount of cells of different types, especially generative cells (GCs), from the pollen. Here, we optimized the conditions of tomato pollen germination and pollen tube growth to allow for long-term growth of pollen tubes in vitro with SCs generated in the tube. Using this culture system, we developed methods for isolating GCs, SCs and vegetative cell nuclei (VN) from just-germinated tomato pollen grains and growing pollen tubes and their purification by Percoll density gradient centrifugation. The purity and viability of isolated GCs and SCs were confirmed by microscopy examination and fluorescein diacetate staining, respectively, and the integrity of VN was confirmed by propidium iodide staining. We could obtain about 1.5 million GCs and 2.0 million SCs each from 180 mg initiated pollen grains, and 10 million VN from 270 mg initiated pollen grains germinated in vitro in each experiment. These methods provide the necessary preconditions for systematic biology studies of SC development and differentiation in higher plants.

  14. A method to study response of large trees to different amounts of available soil water

    Science.gov (United States)

    D.H. Marx; Shi-Jean S. Sung; J.S. Cunningham; M.D. Thompson; L.M. White

    1995-01-01

    A method was developed to manipulate available soil water on large trees by intercepting thrufall with gutters placed under tree canopies and irrigating the intercepted thrufall onto other trees. With this design, trees were exposed for 2 years to either 25% less thrufall, normal thrufall, or 25% additional thrufall.Undercanopy construction in these plots moderately...

  15. Gastrointestinal absorption of large amounts of plutonium. Effect of valency state on transfer

    International Nuclear Information System (INIS)

    Lataillade, G.; Duserre, C.; Metivier, H.; Madic, C.; CEA Centre d'Etudes Nucleaires de Fontenay-aux-Roses, 92

    1989-01-01

    The gastrointestinal absorption of Pu, ingested in valency state III, IV, V or VI was studied in baboons. For each state, the absorption of Pu from masses ranging from 1 to 7 mg per kg of body weight was compared with that from masses ranging from 5 to 45 μg per kg of body weight. The mass ingested did not affect the gastrointestinal absorption of Pu(IV) or PU(VI), but for Pu(V) and to a lesser extent Pu(III), absorption clearly increased about 150-fold and 7-fold respectively, when large masses of Pu were ingested. When small masses were ingested, the valency state did not affect absorption. The increased Pu absorption observed after ingestion of large masses of Pu(V) or (III) might be due to the weak hydrolysis of these valency states. (author)

  16. Nonlinear adaptive synchronization rule for identification of a large amount of parameters in dynamical models

    International Nuclear Information System (INIS)

    Ma Huanfei; Lin Wei

    2009-01-01

    The existing adaptive synchronization technique based on the stability theory and invariance principle of dynamical systems, though theoretically proved to be valid for parameters identification in specific models, is always showing slow convergence rate and even failed in practice when the number of parameters becomes large. Here, for parameters update, a novel nonlinear adaptive rule is proposed to accelerate the rate. Its feasibility is validated by analytical arguments as well as by specific parameters identification in the Lotka-Volterra model with multiple species. Two adjustable factors in this rule influence the identification accuracy, which means that a proper choice of these factors leads to an optimal performance of this rule. In addition, a feasible method for avoiding the occurrence of the approximate linear dependence among terms with parameters on the synchronized manifold is also proposed.

  17. Multifocal Extranodal Involvement of Diffuse Large B-Cell Lymphoma

    Directory of Open Access Journals (Sweden)

    Devrim Cabuk

    2013-01-01

    Full Text Available Endobronchial involvement of extrapulmonary malignant tumors is uncommon and mostly associated with breast, kidney, colon, and rectum carcinomas. A 68-year-old male with a prior diagnosis of colon non-Hodgkin lymphoma (NHL was admitted to the hospital with a complaint of cough, sputum, and dyspnea. The chest radiograph showed right hilar enlargement and opacity at the right middle zone suggestive of a mass lesion. Computed tomography of thorax revealed a right-sided mass lesion extending to thoracic wall with the destruction of the third and the fourth ribs and a right hilar mass lesion. Fiberoptic bronchoscopy was performed in order to evaluate endobronchial involvement and showed stenosis with mucosal tumor infiltration in right upper lobe bronchus. The pathological examination of bronchoscopic biopsy specimen reported diffuse large B-cell lymphoma and the patient was accepted as the endobronchial recurrence of sigmoid colon NHL. The patient is still under treatment of R-ICE (rituximab-ifosfamide-carboplatin-etoposide chemotherapy and partial regression of pulmonary lesions was noted after 3 courses of treatment.

  18. Metal-Oxide Film Conversions Involving Large Anions

    International Nuclear Information System (INIS)

    Pretty, S.; Zhang, X.; Shoesmith, D.W.; Wren, J.C.

    2008-01-01

    The main objective of my research is to establish the mechanism and kinetics of metal-oxide film conversions involving large anions (I - , Br - , S 2- ). Within a given group, the anions will provide insight on the effect of anion size on the film conversion, while comparison of Group 6 and Group 7 anions will provide insight on the effect of anion charge. This research has a range of industrial applications, for example, hazardous radioiodine can be immobilized by reaction with Ag to yield AgI. From the perspective of public safety, radioiodine is one of the most important fission products from the uranium fuel because of its large fuel inventory, high volatility, and radiological hazard. Additionally, because of its mobility, the gaseous iodine concentration is a critical parameter for safety assessment and post-accident management. A full kinetic analysis using electrochemical techniques has been performed on the conversion of Ag 2 O to (1) AgI and (2) AgBr. (authors)

  19. Metal-Oxide Film Conversions Involving Large Anions

    Energy Technology Data Exchange (ETDEWEB)

    Pretty, S.; Zhang, X.; Shoesmith, D.W.; Wren, J.C. [The University of Western Ontario, Chemistry Department, 1151 Richmond St., N6A 5B7, London, Ontario (Canada)

    2008-07-01

    The main objective of my research is to establish the mechanism and kinetics of metal-oxide film conversions involving large anions (I{sup -}, Br{sup -}, S{sup 2-}). Within a given group, the anions will provide insight on the effect of anion size on the film conversion, while comparison of Group 6 and Group 7 anions will provide insight on the effect of anion charge. This research has a range of industrial applications, for example, hazardous radioiodine can be immobilized by reaction with Ag to yield AgI. From the perspective of public safety, radioiodine is one of the most important fission products from the uranium fuel because of its large fuel inventory, high volatility, and radiological hazard. Additionally, because of its mobility, the gaseous iodine concentration is a critical parameter for safety assessment and post-accident management. A full kinetic analysis using electrochemical techniques has been performed on the conversion of Ag{sub 2}O to (1) AgI and (2) AgBr. (authors)

  20. Impacts of large amounts of wind power on design and operation of power systems, results of IEA collaboration

    DEFF Research Database (Denmark)

    Holttinen, Hannele; Meibom, Peter; Orths, Antje

    2011-01-01

    There are dozens of studies made and ongoing related to wind integration. However, the results are not easy to compare. IEA WIND R&D Task 25 on Design and Operation of Power Systems with Large Amounts of Wind Power collects and shares information on wind generation impacts on power systems......, with analyses and guidelines on methodologies. In the state-of-the-art report (October, 2007), and the final report of the 3 years period (July, 2009) the most relevant wind power grid integration studies have been analysed especially regarding methodologies and input data. Several issues that impact...... on the amount of wind power that can be integrated have been identified. Large balancing areas and aggregation benefits of wide areas help in reducing the variability and forecast errors of wind power as well as help in pooling more cost effective balancing resources. System operation and functioning...

  1. A large amount synthesis of nanopowder using modulated induction thermal plasmas synchronized with intermittent feeding of raw materials

    International Nuclear Information System (INIS)

    Tanaka, Y; Tsuke, T; Guo, W; Uesugi, Y; Ishijima, T; Watanabe, S; Nakamura, K

    2012-01-01

    A large amount synthesis method for titanium dioxide (TiO 2 ) nanopowder is proposed by direct evaporation of titanium powders using Ar-O 2 pulse-modulated induction thermal plasma (PMITP). To realize a large amount synthesis of nanopowder, the PMITP method was combined with the intermittent and heavy load feeding of raw material powder, as well as the quenching gas injection. The intermittent powder feeding was synchronized with the modulation of the coil current sustaining the PMITP for complete evaporation of the injected powder. Synthesized particles by the developed method were analyzed by FE-SEM and XRD. Results indicated that the synthesized particles by the 20-kW PMITP with a heavy loading rate of 12.3 g min −1 had a similar particle size distribution with the mean diameter about 40 nm to those with light loading of 4.2 g min −1 .

  2. A Case of Special Complication following a Large Amount of Polyacrylamide Hydrogel Injected into the Epicranial Aponeurosis: Leukocytopenia

    Directory of Open Access Journals (Sweden)

    Li Rong

    2015-01-01

    Full Text Available Polyacrylamide hydrogel (PAAG has been used as an injectable filler for soft tissue augmentation of different body parts, such as the face, breasts, and penis. However, this is the first report of leukocytopenia after injection of a large amount of PAAG in the epicranial aponeurosis. After receiving PAAG injection for craniofacial contouring, the female patient described herein experienced recurrent swelling, temporal pain (particularly with changes in ambient temperature and facial expression, and ultimately leukocytopenia due to widespread migration of the injected PAAG. We removed most of the PAAG from the affected tissues and the leukocytopenia disappeared 1 year after the operation. Based on this case, we hypothesize that injection of a large amount of PAAG into tissues that have ample blood supply, such as the epicranial aponeurosis, may induce leukocytopenia.

  3. Sample preparation method for ICP-MS measurement of 99Tc in a large amount of environmental samples

    International Nuclear Information System (INIS)

    Kondo, M.; Seki, R.

    2002-01-01

    Sample preparation for measurement of 99 Tc in a large amount of soil and water samples by ICP-MS has been developed using 95m Tc as a yield tracer. This method is based on the conventional method for a small amount of soil samples using incineration, acid digestion, extraction chromatography (TEVA resin) and ICP-MS measurement. Preliminary concentration of Tc has been introduced by co-precipitation with ferric oxide. The matrix materials in a large amount of samples were more sufficiently removed with keeping the high recovery of Tc than previous method. The recovery of Tc was 70-80% for 100 g soil samples and 60-70% for 500 g of soil and 500 L of water samples. The detection limit of this method was evaluated as 0.054 mBq/kg in 500 g soil and 0.032 μBq/L in 500 L water. The determined value of 99 Tc in the IAEA-375 (soil sample collected near the Chernobyl Nuclear Reactor) was 0.25 ± 0.02 Bq/kg. (author)

  4. Highly Sensitive GMO Detection Using Real-Time PCR with a Large Amount of DNA Template: Single-Laboratory Validation.

    Science.gov (United States)

    Mano, Junichi; Hatano, Shuko; Nagatomi, Yasuaki; Futo, Satoshi; Takabatake, Reona; Kitta, Kazumi

    2018-03-01

    Current genetically modified organism (GMO) detection methods allow for sensitive detection. However, a further increase in sensitivity will enable more efficient testing for large grain samples and reliable testing for processed foods. In this study, we investigated real-time PCR-based GMO detection methods using a large amount of DNA template. We selected target sequences that are commonly introduced into many kinds of GM crops, i.e., 35S promoter and nopaline synthase (NOS) terminator. This makes the newly developed method applicable to a wide range of GMOs, including some unauthorized ones. The estimated LOD of the new method was 0.005% of GM maize events; to the best of our knowledge, this method is the most sensitive among the GM maize detection methods for which the LOD was evaluated in terms of GMO content. A 10-fold increase in the DNA amount as compared with the amount used under common testing conditions gave an approximately 10-fold reduction in the LOD without PCR inhibition. Our method is applicable to various analytical samples, including processed foods. The use of other primers and fluorescence probes would permit highly sensitive detection of various recombinant DNA sequences besides the 35S promoter and NOS terminator.

  5. Consistency check of iron and sodium cross sections with integral benchmark experiments using a large amount of experimental information

    International Nuclear Information System (INIS)

    Baechle, R.-D.; Hehn, G.; Pfister, G.; Perlini, G.; Matthes, W.

    1984-01-01

    Single material benchmark experiments are designed to check neutron and gamma cross-sections of importance for deep penetration problems. At various penetration depths a large number of activation detectors and spectrometers are placed to measure the radiation field as completely as possible. The large amount of measured data in benchmark experiments can be evaluated best by the global detector concept applied to nuclear data adjustment. A new iteration procedure is presented for adjustment of a large number of multigroup cross sections, which has been implemented now in the modular adjustment code ADJUST-EUR. A theoretical test problem has been deviced to check the total program system with high precision. The method and code are going to be applied for validating the new European Data Files (JEF and EFF) in progress. (Auth.)

  6. The Application Law of Large Numbers That Predicts The Amount of Actual Loss in Insurance of Life

    Science.gov (United States)

    Tinungki, Georgina Maria

    2018-03-01

    The law of large numbers is a statistical concept that calculates the average number of events or risks in a sample or population to predict something. The larger the population is calculated, the more accurate predictions. In the field of insurance, the Law of Large Numbers is used to predict the risk of loss or claims of some participants so that the premium can be calculated appropriately. For example there is an average that of every 100 insurance participants, there is one participant who filed an accident claim, then the premium of 100 participants should be able to provide Sum Assured to at least 1 accident claim. The larger the insurance participant is calculated, the more precise the prediction of the calendar and the calculation of the premium. Life insurance, as a tool for risk spread, can only work if a life insurance company is able to bear the same risk in large numbers. Here apply what is called the law of large number. The law of large numbers states that if the amount of exposure to losses increases, then the predicted loss will be closer to the actual loss. The use of the law of large numbers allows the number of losses to be predicted better.

  7. Automated analysis for large amount gaseous fission product gamma-scanning spectra from nuclear power plant and its data mining

    International Nuclear Information System (INIS)

    Weihua Zhang; Kurt Ungar; Ian Hoffman; Ryan Lawrie; Jarmo Ala-Heikkila

    2010-01-01

    Based on the Linssi database and UniSampo/Shaman software, an automated analysis platform has been setup for the analysis of large amounts of gamma-spectra from the primary coolant monitoring systems of a CANDU reactor. Thus, a database inventory of gaseous and volatile fission products in the primary coolant of a CANDU reactor has been established. This database is comprised of 15,000 spectra of radioisotope analysis records. Records from the database inventory were retrieved by a specifically designed data-mining module and subjected to further analysis. Results from the analysis were subsequently used to identify the reactor coolant half-life of 135 Xe and 133 Xe, as well as the correlations of 135 Xe and 88 Kr activities. (author)

  8. Impacts of Large Amounts of Wind Power on Design and Operation of Power Systems; Results of IEA Collaboration

    Energy Technology Data Exchange (ETDEWEB)

    Parsons, B. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Ela, E. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Holttinen, H. [VTT (Finland); Meibom, P. [DTU Riso (Denmark); Orths, A. [Energinet.dk (Denmark); O' Malley, M. [Univ. College Dubline (Ireland); Ummels, B. C. [Delft Univ. of Technology (Netherlands); Tande, J. [SINTEF (Norway); Estanqueiro, A. [INETI (Portugal); Gomez, E. [Univ. Castilla la Mancha (Spain); Smith, J. C. [Utility Wind Integration Group (UWIG), Reston, VA (United States)

    2008-06-01

    There are a multitude of studies completed and ongoing related to the cost of wind integration. However, the results are not easy to compare. An international forum for exchange of knowledge of power system impacts of wind power has been formed under the IEA Implementing Agreement on Wind Energy. IEA WIND R&D Task 25 on “Design and Operation of Power Systems with Large Amounts of Wind Power” produced a state-of-the-art report in October 2007, where the most relevant wind-power grid integration studies were analyzed, especially regarding methodologies and input data. This paper summarizes the results from 18 case studies, with discussion on differences in methodology as well as issues that have been identified to impact the cost of wind integration.

  9. Involving parents from the start: formative evaluation for a large ...

    African Journals Online (AJOL)

    While HIV prevention research conducted among adolescent populations may encounter parental resistance, the active engagement of parents from inception to trial completion may alleviate opposition. In preparation for implementing a large randomised controlled trial (RCT) examining the efficacy of a behavioural ...

  10. Predicted occurrence rate of severe transportation accidents involving large casks

    International Nuclear Information System (INIS)

    Dennis, A.W.

    1978-01-01

    A summary of the results of an investigation of the severities of highway and railroad accidents as they relate to the shipment of large radioactive materials casks is discussed. The accident environments considered are fire, impact, crash, immersion, and puncture. For each of these environments, the accident severities and their predicted frequencies of occurrence are presented. These accident environments are presented in tabular and graphic form to allow the reader to evaluate the probabilities of occurrence of the accident parameter severities he selects

  11. Abnormal binding and disruption in large scale networks involved in human partial seizures

    Directory of Open Access Journals (Sweden)

    Bartolomei Fabrice

    2013-12-01

    Full Text Available There is a marked increase in the amount of electrophysiological and neuroimaging works dealing with the study of large scale brain connectivity in the epileptic brain. Our view of the epileptogenic process in the brain has largely evolved over the last twenty years from the historical concept of “epileptic focus” to a more complex description of “Epileptogenic networks” involved in the genesis and “propagation” of epileptic activities. In particular, a large number of studies have been dedicated to the analysis of intracerebral EEG signals to characterize the dynamic of interactions between brain areas during temporal lobe seizures. These studies have reported that large scale functional connectivity is dramatically altered during seizures, particularly during temporal lobe seizure genesis and development. Dramatic changes in neural synchrony provoked by epileptic rhythms are also responsible for the production of ictal symptoms or changes in patient’s behaviour such as automatisms, emotional changes or consciousness alteration. Beside these studies dedicated to seizures, large-scale network connectivity during the interictal state has also been investigated not only to define biomarkers of epileptogenicity but also to better understand the cognitive impairments observed between seizures.

  12. Nutrient digestibility of veal calves fed large amounts of different solid feeds during the first 80 days of fattening

    Directory of Open Access Journals (Sweden)

    Marta Brscic

    2014-10-01

    Full Text Available The study aimed at evaluating nutrients apparent digestibility in veal calves fed 3 feeding plans based on milk-replacer plus large amounts of solid feeds differing in their composition during the first 80 days of fattening. Twelve Polish Friesian male calves (70.6±1.9 kg were randomly assigned to one of the following feeding treatments: i milk-replacer plus corn grain (CG; ii milk-replacer plus 80:20 mixture (as fed basis of corn grain and wheat straw (CGS; and iii milk-replacer plus 72:20:8 mixture of corn grain, wheat straw and extruded soybean (CGSES. Calves received the same milk-replacer but the daily amount was restricted (96% for CGSES calves to balance dietary protein. Total dry matter intake from milk-replacer and solid feeds was similar among treatments, but CGSES calves showed better growth performance than CG ones. Calves were introduced into a metabolism stall (1/pen during week 9 of fattening for a 3- day adaptation period and a 4-day digestibility trial. Calves fed CG showed the greatest DM, NFC, and ash digestibility while CGSES calves showed the lowest CP digestibility. Haemoglobin concentrations measured at day 5, 31 and 80 were similar among feeding treatments and significantly decreased over time. In CGSES treatment, the combination of milkreplacer with solid feed closer to a complete diet for ruminants led to better calves’ growth performance. However, the reduced protein digestibility with CGSES indicates that protein quality becomes a key factor when formulating diets for veal calves using alternatives to dairy sources.

  13. A large duplication involving the IHH locus mimics acrocallosal syndrome.

    Science.gov (United States)

    Yuksel-Apak, Memnune; Bögershausen, Nina; Pawlik, Barbara; Li, Yun; Apak, Selcuk; Uyguner, Oya; Milz, Esther; Nürnberg, Gudrun; Karaman, Birsen; Gülgören, Ayan; Grzeschik, Karl-Heinz; Nürnberg, Peter; Kayserili, Hülya; Wollnik, Bernd

    2012-06-01

    Indian hedgehog (Ihh) signaling is a major determinant of various processes during embryonic development and has a pivotal role in embryonic skeletal development. A specific spatial and temporal expression of Ihh within the developing limb buds is essential for accurate digit outgrowth and correct digit number. Although missense mutations in IHH cause brachydactyly type A1, small tandem duplications involving the IHH locus have recently been described in patients with mild syndactyly and craniosynostosis. In contrast, a ∼600-kb deletion 5' of IHH in the doublefoot mouse mutant (Dbf) leads to severe polydactyly without craniosynostosis, but with craniofacial dysmorphism. We now present a patient resembling acrocallosal syndrome (ACS) with extensive polysyndactyly of the hands and feet, craniofacial abnormalities including macrocephaly, agenesis of the corpus callosum, dysplastic and low-set ears, severe hypertelorism and profound psychomotor delay. Single-nucleotide polymorphism (SNP) array copy number analysis identified a ∼900-kb duplication of the IHH locus, which was confirmed by an independent quantitative method. A fetus from a second pregnancy of the mother by a different spouse showed similar craniofacial and limb malformations and the same duplication of the IHH-locus. We defined the exact breakpoints and showed that the duplications are identical tandem duplications in both sibs. No copy number changes were observed in the healthy mother. To our knowledge, this is the first report of a human phenotype similar to the Dbf mutant and strikingly overlapping with ACS that is caused by a copy number variation involving the IHH locus on chromosome 2q35.

  14. Determination of trace amounts of uranium in silicate materials by means of neutron activation analysis involving rapid radiochemical separation

    International Nuclear Information System (INIS)

    Ebihara, M.; Tomura, Kenji; Masutani, M.

    1987-01-01

    Uranium is determined in silicate materials such as standard rocks and a meteorite by radiochemical neutron activation analysis. The gamma-ray intensity of 239 U was measured with a planar type pure germanium detector system. The obtained data are mostly consistent with the literature values. Compared with a non-destructive method, the present method was found to improve the sensitivity by at least a factor of ten. Several errors which might be involved in the authors' RNAA procedures were examined and their degrees were evaluated. (author)

  15. Proposal of the concept of selection of accidents that release large amounts of radioactive substances in the high temperature engineering test reactor

    International Nuclear Information System (INIS)

    Ono, Masato; Honda, Yuki; Takada, Shoji; Sawa, Kazuhiro

    2015-01-01

    In Position, construction and equipment of testing and research reactor to be subjected to the use standards for rules Article 53 (prevention of expansion of the accident to release a large amount of radioactive material) generation the frequency is a lower accident than design basis accident, when what is likely to release a large amount of radioactive material or radiation from the facility has occurred, and take the necessary measures in order to prevent the spread of the accident. There is provided a lower accident than frequency design basis accidents, for those that may release a large amount of radioactive material or radiation. (author)

  16. Effects of interactive transport and scavenging of smoke on the calculated temperature change resulting from large amounts of smoke

    International Nuclear Information System (INIS)

    MacCracken, M.C.; Walton, J.J.

    1984-12-01

    Several theoretical studies with numerical models have shown that substantial land-surface cooling can occur if very large amounts (approx. 100 x 10 12 = 100 Tg) of highly absorbing sooty-particles are injected high into the troposphere and spread instantaneously around the hemisphere (Turco et al., 1983; Covey et al. 1984; MacCracken, 1983). A preliminary step beyond these initial calculations has been made by interactively coupling the two-layer, three-dimensional Oregon State University general circulation model (GCM) to the three-dimensional GRANTOUR trace species model developed at the Lawrence Livermore National Laboratory. The GCM simulation includes treatment of tropospheric dynamics and thermodynamics and the effect of soot on solar radiation. The GRANTOUR simulation includes treatment of particle transport and scavenging by precipitation, although no satisfactory verification of the scavenging algorithm has yet been possible. We have considered the climatic effects of 150 Tg (i.e., the 100 Mt urban war scenario from Turco et al., 1983) and of 15 Tg of smoke from urban fires over North America and Eurasia. Starting with a perpetual July atmospheric situation, calculation of the climatic effects as 150 Tg of smoke are spread slowly by the winds, rather than instantaneously dispersed as in previous calculations, leads to some regions of greater cooling under the denser parts of the smoke plumes and some regions of less severe cooling where smoke arrival is delayed. As for the previous calculations, mid-latitude decreases of land surface air temperature for the 150 Tg injection are greater than 15 0 C after a few weeks. For a 15 Tg injection, however, cooling of more than several degrees centigrade only occurs in limited regions under the dense smoke plumes present in the first few weeks after the injection. 10 references, 9 figures

  17. Determination of small amounts of nitric acid in the presence of large amounts of uranium (VI) and extraction of nitric acid into TBP solutions highly loaded with uranyl nitrate

    International Nuclear Information System (INIS)

    Kolarik, Z.; Schuler, R.

    1982-10-01

    A new method for the determination of small amounts of nitric acid in the presence of large amounts of uranium(VI) was elaborated. The method is based on the precipitation of uranium(VI) as iodate and subsequent alkalimetric titration of the acid in the supernatant. The extraction of nitric acid and uranium(VI) with 30% TBP in dodecane was studied at high loading of the organic phase with uranyl nitrate and at 25, 40 and 60 0 C. The results are compared with available published data on the extraction of nitric acid under similar conditions. (orig.) [de

  18. Endometriosis doubles the risk of sexual dysfunction: a cross-sectional study in a large amount of patients.

    Science.gov (United States)

    Fairbanks, Flávia; Abdo, Carmita Helena; Baracat, Edmund C; Podgaec, Sergio

    2017-07-01

    Endometriosis affects several aspects of a woman's life, including sexual function, but which specific aspects of sexual function remains unclear. A cross-sectional study was performed involving 1001 women divided into two groups, according to the presence or absence of endometriosis. We assessed sexual function, anxiety and depression of patients and correlated these findings with symptoms, locations and types of endometriosis and the affected domains of sexual function. Eighteen completed the forms incorrectly, 294 women (29.9%) were excluded due to severe anxiety and depression. One hundred and six patients had symptoms that could have any relation to endometriosis, so they were also excluded. The final cohort was composed of 254 patients with endometriosis and 329 patients without the disease. Sexual function score was assessed using the female sexual quotient (FSQ); Beck inventories were used to assess anxiety and depression. Patients with endometriosis were affected in all phases of sexual response: desire, sexual arousal, genital-pelvic pain/ penetration and orgasm/ sexual satisfaction. In the overall assessment, 43.3% of patients with endometriosis had sexual dysfunction, while the population without endometriosis sexual dysfunction occurred in 17.6% of women. Patients with endometriosis have more than twice sexual dysfunctions as compared to women without the disease.

  19. Ultra trace analysis of PAHs by designing simple injection of large amounts of analytes through the sample reconcentration on SPME fiber after magnetic solid phase extraction.

    Science.gov (United States)

    Khodaee, Nader; Mehdinia, Ali; Esfandiarnejad, Reyhaneh; Jabbari, Ali

    2016-01-15

    A simple solventless injection method was introduced based on the using of a solid-phase microextraction (SPME) fiber for injection of large amounts of the analytes extracted by the magnetic solid phase extraction (MSPE) procedure. The resulted extract from MSPE procedure was loaded on a G-coated SPME fiber, and then the fiber was injected into the gas chromatography (GC) injection port. This method combines the advantages of exhaustive extraction property of MSPE and the solvent-less injection of SPME to improve the sensitivity of the analysis. In addition, the analytes were re-concentrated prior to inject into the gas chromatography (GC) inlet because of the organic solvent removing from the remaining extract of MSPE technique. Injection of the large amounts of analytes was made possible by using the introduced procedure. Fourteen polycyclic aromatic hydrocarbons (PAHs) with different volatility were used as model compounds to investigate the method performance for volatile and semi-volatile compounds. The introduced method resulted in the higher enhancement factors (5097-59376), lower detection limits (0.29-3.3pgmL(-1)), and higher sensitivity for the semi-volatile compounds compared with the conventional direct injection method. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Iron Malabsorption in a Patient With Large Cell Lymphoma Involving the Duodenum

    Science.gov (United States)

    1992-01-01

    hemoglobin. The lymphomas (5-7). The presenting symptoms mimic chest radiograph in May demonstrated an anterior me- those of celiac disease and include...compounded the anemia in a pa- tion in celiac disease were reversible by the institution tient with diffuse large cell lymphoma involving the of a gluten...etiologies (usually 2-3 h) is expected in patients who are iron (e.g., celiac disease , pancreatic insufliciency). however, deficient and have normal

  1. Isolated cutaneous involvement in a child with nodal anaplastic large cell lymphoma

    Directory of Open Access Journals (Sweden)

    Vibhu Mendiratta

    2016-01-01

    Full Text Available Non-Hodgkin lymphoma is a common childhood T-cell and B-cell neoplasm that originates primarily from lymphoid tissue. Cutaneous involvement can be in the form of a primary extranodal lymphoma, or secondary to metastasis from a non-cutaneous location. The latter is uncommon, and isolated cutaneous involvement is rarely reported. We report a case of isolated secondary cutaneous involvement from nodal anaplastic large cell lymphoma (CD30 + and ALK + in a 7-year-old boy who was on chemotherapy. This case is reported for its unusual clinical presentation as an acute febrile, generalized papulonodular eruption that mimicked deep fungal infection, with the absence of other foci of systemic metastasis.

  2. ALK-positive anaplastic large cell lymphoma with soft tissue involvement in a young woman

    Directory of Open Access Journals (Sweden)

    Gao KH

    2016-07-01

    Full Text Available Kehai Gao, Hongtao Li, Caihong Huang, Huazhuang Li, Jun Fang, Chen Tian Department of Orthopaedics, Yidu Central Hospital, Shandong, People’s Republic of China Introduction: Anaplastic large cell lymphoma (ALCL is a type of non-Hodgkin lymphoma that has strong expression of CD30. ALCL can sometimes involve the bone marrow, and in advanced stages, it can produce destructive extranodal lesions. But anaplastic large cell lymphoma kinase (ALK+ ALCL with soft tissue involvement is very rare.Case report: A 35-year-old woman presented with waist pain for over 1 month. The biopsy of soft tissue lesions showed that these cells were positive for ALK-1, CD30, TIA-1, GranzymeB, CD4, CD8, and Ki67 (90%+ and negative for CD3, CD5, CD20, CD10, cytokeratin (CK, TdT, HMB-45, epithelial membrane antigen (EMA, and pan-CK, which identified ALCL. After six cycles of Hyper-CVAD/MA regimen, she achieved partial remission. Three months later, she died due to disease progression.Conclusion: This case illustrates the unusual presentation of ALCL in soft tissue with a bad response to chemotherapy. Because of the tendency for rapid progression, ALCL in young adults with extranodal lesions are often treated with high-grade chemotherapy, such as Hyper-CVAD/MA. Keywords: anaplastic large cell lymphoma, ALK+, soft tissue involvement, Hyper-CVAD/MA

  3. Secondary pancreatic involvement by a diffuse large B-cell lymphoma presenting as acute pancreatitis

    Institute of Scientific and Technical Information of China (English)

    M Wasif Saif; Sapna Khubchandani; Marek Walczak

    2007-01-01

    Diffuse large B-cell lymphoma is the most common type of non-Hodgkin's lymphoma. More than 50% of patients have some site of extra-nodal involvement at diagnosis,including the gastrointestinal tract and bone marrow.However, a diffuse large B-cell lymphoma presenting as acute pancreatitis is rare. A 57-year-old female presented with abdominal pain and matted lymph nodes in her axilla. She was admitted with a diagnosis of acute pancreatitis. Abdominal computed tomography (CT) scan showed diffusely enlarged pancreas due to infiltrative neoplasm and peripancreatic lymphadenopathy. Biopsy of the axillary mass revealed a large B-cell lymphoma.The patient was classified as stage Ⅳ, based on the Ann Arbor Classification, and as having a high-risk lymphoma,based on the International Prognostic Index. She was started on chemotherapy with CHOP (cyclophosphamide,doxorubicin, vincristine and prednisone). Within a week after chemotherapy, the patient's abdominal pain resolved. Follow-up CT scan of the abdomen revealed a marked decrease in the size of the pancreas and peripancreatic lymphadenopathy. A literature search revealed only seven cases of primary involvement of the pancreas in B-cell lymphoma presenting as acute pancreatitis. However, only one case of secondary pancreatic involvement by B-cell lymphoma presenting as acute pancreatitis has been published. Our case appears to be the second report of such a manifestation.Both cases responded well to chemotherapy.

  4. Does thinking and doing the same thing amount to involved participation? Empirical explorations for finding a measure of intensity for a third ICF-CY qualifier.

    Science.gov (United States)

    Maxwell, Gregor; Augustine, Lilly; Granlund, Mats

    2012-01-01

    Participation as involvement in a situation includes two dimensions; doing the activity and the experience of involvement. The ICF-CY only measures doing using the capacity and performance qualifiers, a dimension measuring the experience is needed; a third qualifier. The experienced involvement of pupils in school activities is higher when thinking and doing coincided. By comparing self-reported experiences of involvement of children, data about what children were thinking and doing during activities were gathered from 21 children with and 19 without disabilities in inclusive classrooms. A relationship exists between an index of the subjective experience of involvement and whether children were thinking and doing the same things. This index can be constructed using measures of concentration, control, involvement, and motivation. Choice is influential, as knowledge about why an activity is undertaken affects involvement. Additionally, increased subjective experience of involvement gives better psychological health and well-being.

  5. Mesothelioma With a Large Prevascular Lymph Node: N1 Involvement or Something Different?

    Science.gov (United States)

    Berzenji, Lawek; Van Schil, Paul E; Snoeckx, Annemie; Hertoghs, Marjan; Carp, Laurens

    2018-05-01

    A 64-year-old man presented with a large amount of right-sided pleural fluid on imaging, together with calcified pleural plaques and an enlarged nodular structure in the prevascular mediastinum, presumably an enlarged lymph node. Pleural biopsies were obtained during video-assisted thoracoscopic surgery to exclude malignancy. Histopathology showed an epithelial malignant pleural mesothelioma. Induction chemotherapy with cisplatin and pemetrexed was administered followed by an extended pleurectomy and decortication with systematic nodal dissection. Histopathology confirmed the diagnosis of a ypT3N0M0 (stage IB) mesothelioma, and an unexpected thymoma type B2 (stage II) was discovered in the prevascular nodule. Simultaneous occurrence of a mesothelioma and thymoma is extremely rare. Copyright © 2018 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  6. Investigation of large α production in reactions involving weakly bound 7Li

    Science.gov (United States)

    Pandit, S. K.; Shrivastava, A.; Mahata, K.; Parkar, V. V.; Palit, R.; Keeley, N.; Rout, P. C.; Kumar, A.; Ramachandran, K.; Bhattacharyya, S.; Nanal, V.; Palshetkar, C. S.; Nag, T. N.; Gupta, Shilpi; Biswas, S.; Saha, S.; Sethi, J.; Singh, P.; Chatterjee, A.; Kailas, S.

    2017-10-01

    The origin of the large α -particle production cross sections in systems involving weakly bound 7Li projectiles has been investigated by measuring the cross sections of all possible fragment-capture as well as complete fusion using the particle-γ coincidence, in-beam, and off-beam γ -ray counting techniques for the 7Li+93Nb system at near Coulomb barrier energies. Almost all of the inclusive α -particle yield has been accounted for. While the t -capture mechanism is found to be dominant (˜70 % ), compound nuclear evaporation and breakup processes contribute ˜15 % each to the inclusive α -particle production in the measured energy range. Systematic behavior of the t capture and inclusive α cross sections for reactions involving 7Li over a wide mass range is also reported.

  7. Synthesis of biodiesel from waste vegetable oil with large amounts of free fatty acids using a carbon-based solid acid catalyst

    Energy Technology Data Exchange (ETDEWEB)

    Shu, Qing; Gao, Jixian; Nawaz, Zeeshan; Liao, Yuhui; Wang, Dezheng; Wang, Jinfu [Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology, Department of Chemical Engineering, Tsinghua University, Beijing 100084 (China)

    2010-08-15

    A carbon-based solid acid catalyst was prepared by the sulfonation of carbonized vegetable oil asphalt. This catalyst was employed to simultaneously catalyze esterification and transesterification to synthesis biodiesel when a waste vegetable oil with large amounts of free fatty acids (FFAs) was used as feedstock. The physical and chemical properties of this catalyst were characterized by a variety of techniques. The maximum conversion of triglyceride and FFA reached 80.5 wt.% and 94.8 wt.% after 4.5 h at 220 C, when using a 16.8 M ratio of methanol to oil and 0.2 wt.% of catalyst to oil. The high catalytic activity and stability of this catalyst was related to its high acid site density (-OH, Broensted acid sites), hydrophobicity that prevented the hydration of -OH species, hydrophilic functional groups (-SO{sub 3}H) that gave improved accessibility of methanol to the triglyceride and FFAs, and large pores that provided more acid sites for the reactants. (author)

  8. Risk of a large amount of high-radioactive contaminated water leaking into the reactor building basement of Fukushima Daiichi nuclear power station

    International Nuclear Information System (INIS)

    Ebisawa, Toru; Sawai, Masako

    2013-01-01

    In November 2012 about one and half year after the accident at units 1, 2 and 3 of Fukushima Daiichi nuclear power station, some 405 m 3 /day cooling water was being injected into the melt damaged core and leaked as highly-radioactive contaminated water from damaged lower part of containment into the basement of turbine hall. To treat a large amount of contaminated water in the basement, waste processing plant to remove cesium was installed in June 2011 with desalination plant, which produced clean water for circulating coolant system of damaged nuclear fuel while the rest went to storage. Radioactivity of contaminated water in the basement accumulated at initial almost 80 days of the accident was evaluated about 20% for Cs-137 of core inventory of units 1, 2 and 3 and 2.3% for Sr-90 of core inventory of units 2 and 3. Sr-90 from unit 1 was not released into the basement and almost remained at suppression chamber. By November 2012, Cs-137 released into the basement was evaluated to total about 40% of core inventory and stored contaminated water amounted to about 360 kilotons, while Cs-137 released into the atmosphere was estimated about 3.6% of core inventory with its one third contributed for land contamination. Sr-90 released into the basement was estimated as 6.3% or 4.4% of core inventory based on Sr-90 measured activity of treated water in December or September 2011 with stored contaminated water of 300 kilotons. Cs-137 and Sr-90 contaminated water kept continuously releasing into the basement as long as melt damaged core existed and cooling water washed out Cs-137 and Sr-90 attached on containment walls. Safe store of released radioactivity was highly important and acquired important data was recommended to publish for check and review. (T. Tanaka)

  9. Data-based method for creating electricity use load profiles using large amount of customer-specific hourly measured electricity use data

    International Nuclear Information System (INIS)

    Raesaenen, Teemu; Voukantsis, Dimitrios; Niska, Harri; Karatzas, Kostas; Kolehmainen, Mikko

    2010-01-01

    The recent technological developments monitoring the electricity use of small customers provides with a whole new view to develop electricity distribution systems, customer-specific services and to increase energy efficiency. The analysis of customer load profile and load estimation is an important and popular area of electricity distribution technology and management. In this paper, we present an efficient methodology, based on self-organizing maps (SOM) and clustering methods (K-means and hierarchical clustering), capable of handling large amounts of time-series data in the context of electricity load management research. The proposed methodology was applied on a dataset consisting of hourly measured electricity use data, for 3989 small customers located in Northern-Savo, Finland. Information for the hourly electricity use, for a large numbers of small customers, has been made available only recently. Therefore, this paper presents the first results of making use of these data. The individual customers were classified into user groups based on their electricity use profile. On this basis, new, data-based load curves were calculated for each of these user groups. The new user groups as well as the new-estimated load curves were compared with the existing ones, which were calculated by the electricity company, on the basis of a customer classification scheme and their annual demand for electricity. The index of agreement statistics were used to quantify the agreement between the estimated and observed electricity use. The results indicate that there is a clear improvement when using data-based estimations, while the new-estimated load curves can be utilized directly by existing electricity power systems for more accurate load estimates.

  10. Data-based method for creating electricity use load profiles using large amount of customer-specific hourly measured electricity use data

    Energy Technology Data Exchange (ETDEWEB)

    Raesaenen, Teemu; Niska, Harri; Kolehmainen, Mikko [Department of Environmental Sciences, University of Eastern Finland P.O. Box 1627, FIN-70211 Kuopio (Finland); Voukantsis, Dimitrios; Karatzas, Kostas [Department of Mechanical Engineering, Aristotle University of Thessaloniki, GR-54124 Thessaloniki (Greece)

    2010-11-15

    The recent technological developments monitoring the electricity use of small customers provides with a whole new view to develop electricity distribution systems, customer-specific services and to increase energy efficiency. The analysis of customer load profile and load estimation is an important and popular area of electricity distribution technology and management. In this paper, we present an efficient methodology, based on self-organizing maps (SOM) and clustering methods (K-means and hierarchical clustering), capable of handling large amounts of time-series data in the context of electricity load management research. The proposed methodology was applied on a dataset consisting of hourly measured electricity use data, for 3989 small customers located in Northern-Savo, Finland. Information for the hourly electricity use, for a large numbers of small customers, has been made available only recently. Therefore, this paper presents the first results of making use of these data. The individual customers were classified into user groups based on their electricity use profile. On this basis, new, data-based load curves were calculated for each of these user groups. The new user groups as well as the new-estimated load curves were compared with the existing ones, which were calculated by the electricity company, on the basis of a customer classification scheme and their annual demand for electricity. The index of agreement statistics were used to quantify the agreement between the estimated and observed electricity use. The results indicate that there is a clear improvement when using data-based estimations, while the new-estimated load curves can be utilized directly by existing electricity power systems for more accurate load estimates. (author)

  11. Questionnaire: involved actors in large disused components management - Summary Of Responses To The Questionnaire

    International Nuclear Information System (INIS)

    2012-01-01

    The aim of the Questionnaire is to establish an overview of the various bodies [Actors] that have responsibilities or input to the issue of large component decommissioning. In answering the intent is to cover the overall organisation and those bits that have most relevance to large components. The answers should reflect the areas from site operations to decommissioning as well as the wider issue of disposal at another location. The Questionnaire covers the following points: 1 - What is the country (institutional) structure for decommissioning? 2 - who does what and where lie the responsibilities? 3 - Which bodies have responsibility for onsite safety regulation, discharges and disposal? 4 - Which body(s) owns the facilities? 5 - Describe the responsibilities for funding of the decommissioning plan and disposal plan. Are they one and the same body? Whilst there are differences between countries there are some common threads. Regulation is through the state though the number of regulators involved may vary. In summary, the IAEA principles concerning independence of the regulatory body are followed. Funding arrangements vary but there are plans. Similarly, ownership of facilities is a mix of state and private. Some systems require a separate decommissioning license with Spain having the clearest demarcation of responsibilities for the decommissioning phase and waste management responsibilities

  12. Pituitary and adrenal involvement in diffuse large B-cell lymphoma, with recovery of their function after chemotherapy

    OpenAIRE

    Nakashima, Yasuhiro; Shiratsuchi, Motoaki; Abe, Ichiro; Matsuda, Yayoi; Miyata, Noriyuki; Ohno, Hirofumi; Ikeda, Motohiko; Matsushima, Takamitsu; Nomura, Masatoshi; Takayanagi, Ryoichi

    2013-01-01

    Background Diffuse large B-cell lymphoma sometimes involves the endocrine organs, but involvement of both the pituitary and adrenal glands is extremely rare. Involvement of these structures can lead to hypopituitarism and adrenal insufficiency, and subsequent recovery of their function is rarely seen. The present report describes an extremely rare case of pituitary and adrenal diffuse large B-cell lymphoma presenting with hypopituitarism and adrenal insufficiency with subsequent recovery of p...

  13. Large Amounts of Reactivated Virus in Tears Precedes Recurrent Herpes Stromal Keratitis in Stressed Rabbits Latently Infected with Herpes Simplex Virus.

    Science.gov (United States)

    Perng, Guey-Chuen; Osorio, Nelson; Jiang, Xianzhi; Geertsema, Roger; Hsiang, Chinhui; Brown, Don; BenMohamed, Lbachir; Wechsler, Steven L

    2016-01-01

    Recurrent herpetic stromal keratitis (rHSK), due to an immune response to reactivation of herpes simplex virus (HSV-1), can cause corneal blindness. The development of therapeutic interventions such as drugs and vaccines to decrease rHSK have been hampered by the lack of a small and reliable animal model in which rHSK occurs at a high frequency during HSV-1 latency. The aim of this study is to develop a rabbit model of rHSK in which stress from elevated temperatures increases the frequency of HSV-1 reactivations and rHSK. Rabbits latently infected with HSV-1 were subjected to elevated temperatures and the frequency of viral reactivations and rHSK were determined. In an experiment in which rabbits latently infected with HSV-1 were subjected to ill-defined stress as a result of failure of the vivarium air conditioning system, reactivation of HSV-1 occurred at over twice the normal frequency. In addition, 60% of eyes developed severe rHSK compared to tears of that eye and whenever this unusually large amount of reactivated virus was detected in tears, rHSK always appeared 4-5 days later. In subsequent experiments using well defined heat stress the reactivation frequency was similarly increased, but no eyes developed rHSK. The results reported here support the hypothesis that rHSK is associated not simply with elevated reactivation frequency, but rather with rare episodes of very high levels of reactivated virus in tears 4-5 days earlier.

  14. Atypical profiles and modulations of heme-enzymes catalyzed outcomes by low amounts of diverse additives suggest diffusible radicals' obligatory involvement in such redox reactions.

    Science.gov (United States)

    Manoj, Kelath Murali; Parashar, Abhinav; Venkatachalam, Avanthika; Goyal, Sahil; Satyalipsu; Singh, Preeti Gunjan; Gade, Sudeep K; Periyasami, Kalaiselvi; Jacob, Reeba Susan; Sardar, Debosmita; Singh, Shanikant; Kumar, Rajan; Gideon, Daniel A

    2016-06-01

    Peroxidations mediated by heme-enzymes have been traditionally studied under a single-site (heme distal pocket), non-sequential (ping-pong), two-substrates binding scheme of Michaelis-Menten paradigm. We had reported unusual modulations of peroxidase and P450 reaction outcomes and explained it invoking diffusible reactive species [Manoj, 2006; Manoj et al., 2010; Andrew et al., 2011, Parashar et al., 2014 & Venkatachalam et al., 2016]. A systematic investigation of specific product formation rates was undertaken to probe the hypothesis that involvement of diffusible reactive species could explain undefined substrate specificities and maverick modulations (sponsored by additives) of heme-enzymes. When the rate of specific product formation was studied as a function of reactants' concentration or environmental conditions, we noted marked deviations from normal profiles. We report that heme-enzyme mediated peroxidations of various substrates are inhibited (or activated) by sub-equivalent concentrations of diverse redox-active additives and this is owing to multiple redox equilibriums in the milieu. At low enzyme and peroxide concentrations, the enzyme is seen to recycle via a one-electron (oxidase) cycle, which does not require the substrate to access the heme centre. Schemes are provided that explain the complex mechanistic cycle, kinetics & stoichiometry. It is not obligatory for an inhibitor or substrate to interact with the heme centre for influencing overall catalysis. Roles of diffusible reactive species explain catalytic outcomes at low enzyme and reactant concentrations. The current work highlights the scope/importance of redox enzyme reactions that could occur "out of the active site" in biological or in situ systems. Copyright © 2016 Elsevier B.V. and Société française de biochimie et biologie Moléculaire (SFBBM). All rights reserved.

  15. Patterns of failure of diffuse large B-cell lymphoma patients after involved-site radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Holzhaeuser, Eva; Berlin, Maximilian; Bezold, Thomas; Mayer, Arnulf; Schmidberger, Heinz [University Medical Center Mainz, Department of Radiation Oncology and Radiotherapy, Mainz (Germany); Wollschlaeger, Daniel [University Medical Center Mainz, Institute for Medical Biostatistics, Epidemiology and Informatics, Mainz (Germany); Hess, Georg [University Medical Center Mainz, Department of Internal Medicine, Mainz (Germany)

    2017-12-15

    Radiotherapy (RT) in combination with chemoimmunotherapy is highly efficient in the treatment of diffuse large B-cell lymphoma (DLBCL). This retrospective analysis evaluated the efficacy of the treatment volume and the dose concept of involved-site RT (ISRT). We identified 60 histologically confirmed stage I-IV DLBCL patients treated with multimodal cytotoxic chemoimmunotherapy and followed by consolidative ISRT from 2005-2015. Progression-free survival (PFS) and overall survival (OS) were estimated by Kaplan-Meier method. Univariate analyses were performed by log-rank test and Mann-Whitney U-test. After initial chemoimmunotherapy (mostly R-CHOP; rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone), 19 (36%) patients achieved complete response (CR), 34 (64%) partial response (PR) or less. Excluded were 7 (12%) patients with progressive disease after chemoimmunotherapy. All patients underwent ISRT with a dose of 40 Gy. After a median follow-up of 44 months, 79% of the patients remained disease free, while 21% presented with failure, progressive systemic disease, or death. All patients who achieved CR after chemoimmunotherapy remained in CR. Of the patients achieving PR after chemotherapy only 2 failed at the initial site within the ISRT volume. No marginal relapse was observed. Ann Arbor clinical stage I/II showed significantly improved PFS compared to stage III/IV (93% vs 65%; p ≤ 0.021). International Prognostic Index (IPI) score of 0 or 1 compared to 2-5 has been associated with significantly increased PFS (100% vs 70%; p ≤ 0.031). Postchemoimmunotherapy status of CR compared to PR was associated with significantly increased PFS (100% vs 68%; p ≤ 0.004) and OS (100% vs 82%; p ≤ 0.026). Only 3 of 53 patients developed grade II late side effects, whereas grade III or IV side effects have not been observed. These data suggest that a reduction of the RT treatment volume from involved-field (IF) to involved-site (IS) is sufficient because

  16. Atomic absorption spectrophotometric determination of microgram levels of Co, Ni, Cu, Pb, and Zn in soil and sediment extracts containing large amounts of Mn and Fe

    Science.gov (United States)

    Chao, T.T.; Sanzolone, R.F.

    1973-01-01

    An atomic absorption spectrophotometric method has been developed for the determination of seven metal ions in the hydroxylamine extract of soils and sediments. Mn, Fe, and Zn are directly determined in the aqueous extract upon dilution. Co, Ni, Cu, and Pb in a separate aliquot of the extract are chelated with APDC (ammonium pyrrolidine dithiocarbamate) and extracted into MIBK (methyl isobutyl ketone) before determination. Data are presented to show the quantitative recovery of microgram levels of Co, Ni, Cu, and Pb by APDC-MIBK chelation-extraction from synthetic solutions containing as much as 2,000 ug/ml (micrograms per milliliter) Mn or 50 ug/ml Fe. Recovery of known amounts of the metal ions from sample solutions is equally satisfactory. Reproducible results are obtained by replicate analyses of two sediment samples for the seven metals.

  17. Using Quality Circles to Enhance Student Involvement and Course Quality in a Large Undergraduate Food Science and Human Nutrition Course

    Science.gov (United States)

    Schmidt, S. J.; Parmer, M. S.; Bohn, D. M.

    2005-01-01

    Large undergraduate classes are a challenge to manage, to engage, and to assess, yet such formidable classes can flourish when student participation is facilitated. One method of generating authentic student involvement is implementation of quality circles by means of a Student Feedback Committee (SFC), which is a volunteer problem-solving and…

  18. Emergency preparedness: medical management of nuclear accidents involving large groups of victims

    International Nuclear Information System (INIS)

    Parmentier, N.; Nenot, J.C.

    1988-01-01

    The treatment of overexposed individuals implies hospitalisation in a specialized unit applying hematological intense care. If the accident results in a small number of casualties, the medical management does not raise major problems in most of the countries, where specialized units exist, as roughly 7% of the beds are available at any time. But an accident which would involved tens or hundreds of people raises much more problems for hospitalization. Such problems are also completely different and will involve steps in the medical handling, mainly triage, (combined injuries), determination of whole body dose levels, transient hospitalization. In this case, preplanning is necessary, adapted to the system of medical care in case of a catastrophic event in the given Country, with the main basic principles : emergency concerns essentially the classical injuries (burns and trauma) - and contamination problems in some cases - treatment of radiation syndrome is not an emergency during the first days but some essential actions have to be taken such as early blood sampling for biological dosimetry and for HLa typing

  19. Influence of the reagent concentration of the colorimetric copper determination with sodium diethyl dithiocarbamate (abbreviated: D.D.C.) and its importance for the determination of copper in the presence of large amounts of iron

    NARCIS (Netherlands)

    Karsten, P.; Rademaker, S.C.; Walraven, J.J.

    1950-01-01

    From a research about the influence of the reagent concentration on the copper determination with sodium di-ethyl-di-thio-carbamate in the presence of large amounts of iron some insight was gained into factors which had never been examined so far and which were found to have great influence on the

  20. Heart of Lymphoma: Primary Mediastinal Large B-Cell Lymphoma with Endomyocardial Involvement

    Directory of Open Access Journals (Sweden)

    Elisa Rogowitz

    2013-01-01

    Full Text Available Primary mediastinal B-cell lymphoma (PMBCL is an uncommon aggressive subset of diffuse large B-cell lymphomas. Although PMBCL frequently spreads locally from the thymus into the pleura or pericardium, it rarely invades directly through the heart. Herein, we report a case of a young Mexican female diagnosed with PMBCL with clear infiltration of lymphoma through the cardiac wall and into the right atrium and tricuspid valve leading to tricuspid regurgitation. This was demonstrated by cardiac MRI and transthoracic echocardiogram. In addition, cardiac MRI and CT scan of the chest revealed the large mediastinal mass completely surrounding and eroding into the superior vena cava (SVC wall causing a collar of stokes. The cardiac and SVC infiltration created a significant therapeutic challenge as lymphomas are very responsive to chemotherapy, and treatment could potentially lead to vascular wall rupture and hemorrhage. Despite the lack of conclusive data on chemotherapy-induced hemodynamic compromise in such scenarios, her progressive severe SVC syndrome and respiratory distress necessitated urgent intervention. In addition to the unique presentation of this rare lymphoma, our case report highlights the safety of R-CHOP treatment.

  1. A deployable in vivo EPR tooth dosimeter for triage after a radiation event involving large populations

    International Nuclear Information System (INIS)

    Williams, Benjamin B.; Dong, Ruhong; Flood, Ann Barry; Grinberg, Oleg; Kmiec, Maciej; Lesniewski, Piotr N.; Matthews, Thomas P.; Nicolalde, Roberto J.; Raynolds, Tim; Salikhov, Ildar K.; Swartz, Harold M.

    2011-01-01

    In order to meet the potential need for emergency large-scale retrospective radiation biodosimetry following an accident or attack, we have developed instrumentation and methodology for in vivo electron paramagnetic resonance spectroscopy to quantify concentrations of radiation-induced radicals within intact teeth. This technique has several very desirable characteristics for triage, including independence from confounding biologic factors, a non-invasive measurement procedure, the capability to make measurements at any time after the event, suitability for use by non-expert operators at the site of an event, and the ability to provide immediate estimates of individual doses. Throughout development there has been a particular focus on the need for a deployable system, including instrumental requirements for transport and field use, the need for high throughput, and use by minimally trained operators. Numerous measurements have been performed using this system in clinical and other non-laboratory settings, including in vivo measurements with unexposed populations as well as patients undergoing radiation therapies. The collection and analyses of sets of three serially-acquired spectra with independent placements of the resonator, in a data collection process lasting approximately 5 min, provides dose estimates with standard errors of prediction of approximately 1 Gy. As an example, measurements were performed on incisor teeth of subjects who had either received no irradiation or 2 Gy total body irradiation for prior bone marrow transplantation; this exercise provided a direct and challenging test of our capability to identify subjects who would be in need of acute medical care. -- Highlights: → Advances in radiation biodosimetry are needed for large-scale emergency response. → Radiation-induced radicals in tooth enamel can be measured using in vivo EPR. → A novel transportable spectrometer was applied in the laboratory and at remote sites. → The current

  2. A deployable in vivo EPR tooth dosimeter for triage after a radiation event involving large populations

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Benjamin B., E-mail: Benjamin.B.Williams@dartmouth.edu [Dartmouth Physically Based Biodosimetry Center for Medical Countermeasures Against Radiation (Dart-Dose CMCR), Dartmouth Medical School, Hanover, NH 03768 (United States); Section of Radiation Oncology, Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH (United States); Dong, Ruhong [Dartmouth Physically Based Biodosimetry Center for Medical Countermeasures Against Radiation (Dart-Dose CMCR), Dartmouth Medical School, Hanover, NH 03768 (United States); Flood, Ann Barry [Dartmouth Physically Based Biodosimetry Center for Medical Countermeasures Against Radiation (Dart-Dose CMCR), Dartmouth Medical School, Hanover, NH 03768 (United States); Clin-EPR, LLC, Lyme, NH (United States); Grinberg, Oleg [Clin-EPR, LLC, Lyme, NH (United States); Kmiec, Maciej; Lesniewski, Piotr N.; Matthews, Thomas P.; Nicolalde, Roberto J.; Raynolds, Tim [Dartmouth Physically Based Biodosimetry Center for Medical Countermeasures Against Radiation (Dart-Dose CMCR), Dartmouth Medical School, Hanover, NH 03768 (United States); Salikhov, Ildar K. [Clin-EPR, LLC, Lyme, NH (United States); Swartz, Harold M. [Dartmouth Physically Based Biodosimetry Center for Medical Countermeasures Against Radiation (Dart-Dose CMCR), Dartmouth Medical School, Hanover, NH 03768 (United States); Clin-EPR, LLC, Lyme, NH (United States)

    2011-09-15

    In order to meet the potential need for emergency large-scale retrospective radiation biodosimetry following an accident or attack, we have developed instrumentation and methodology for in vivo electron paramagnetic resonance spectroscopy to quantify concentrations of radiation-induced radicals within intact teeth. This technique has several very desirable characteristics for triage, including independence from confounding biologic factors, a non-invasive measurement procedure, the capability to make measurements at any time after the event, suitability for use by non-expert operators at the site of an event, and the ability to provide immediate estimates of individual doses. Throughout development there has been a particular focus on the need for a deployable system, including instrumental requirements for transport and field use, the need for high throughput, and use by minimally trained operators. Numerous measurements have been performed using this system in clinical and other non-laboratory settings, including in vivo measurements with unexposed populations as well as patients undergoing radiation therapies. The collection and analyses of sets of three serially-acquired spectra with independent placements of the resonator, in a data collection process lasting approximately 5 min, provides dose estimates with standard errors of prediction of approximately 1 Gy. As an example, measurements were performed on incisor teeth of subjects who had either received no irradiation or 2 Gy total body irradiation for prior bone marrow transplantation; this exercise provided a direct and challenging test of our capability to identify subjects who would be in need of acute medical care. -- Highlights: > Advances in radiation biodosimetry are needed for large-scale emergency response. > Radiation-induced radicals in tooth enamel can be measured using in vivo EPR. > A novel transportable spectrometer was applied in the laboratory and at remote sites. > The current instrument

  3. Sequential extraction results in improved proteome profiling of medicinal plant Pinellia ternata tubers, which contain large amounts of high-abundance proteins.

    Directory of Open Access Journals (Sweden)

    Xiaolin Wu

    Full Text Available Pinellia ternata tuber is one of the well-known Chinese traditional medicines. In order to understand the pharmacological properties of tuber proteins, it is necessary to perform proteome analysis of P. ternata tubers. However, a few high-abundance proteins (HAPs, mainly mannose-binding lectin (agglutinin, exist in aggregates of various sizes in the tubers and seriously interfere with proteome profiling by two-dimensional electrophoresis (2-DE. Therefore, selective depletion of these HAPs is a prerequisite for enhanced proteome analysis of P. ternata tubers. Based on differential protein solubility, we developed a novel protocol involving two sequential extractions for depletion of some HAPs and prefractionation of tuber proteins prior to 2-DE. The first extraction using 10% acetic acid selectively extracted acid-soluble HAPs and the second extraction using the SDS-containing buffer extracted remaining acid-insoluble proteins. After application of the protocol, 2-DE profiles of P. ternata tuber proteins were greatly improved and more protein spots were detected, especially low-abundance proteins. Moreover, the subunit composition of P. ternata lectin was analyzed by electrophoresis. Native lectin consists of two hydrogen-bonded subunits (11 kDa and 25 kDa and the 11 kDa subunit was a glycoprotein. Subsequently, major HAPs in the tubers were analyzed by mass spectrometry, with nine protein spots being identified as lectin isoforms. The methodology was easy to perform and required no specialized apparatus. It would be useful for proteome analysis of other tuber plants of Araceae.

  4. Design and operation of power systems with large amounts of wind power. Final summary report, IEA WIND Task 25, Phase two 2009 - 2011

    Energy Technology Data Exchange (ETDEWEB)

    Holttinen, H.; Kiviluoma, J. [VTT Technical Research Centre of Finland, Espoo (Finland); Robitaille, A. [Hydro Quebec, Montreal QC (Canada)] [and others

    2013-01-15

    This report provides a summary of the results from recent wind integration studies. The studies address concerns about the impact of wind power's variability and uncertainty on power system reliability and costs as well as grid reinforcement needs. Quantifiable results are presented as summary graphs: results as a MW-increase in reserve requirements, or euro/MWh increase in balancing costs, or results for capacity value of wind power. Other results are briefly summarised, together with existing experience on the issues. There is already significant experience in integrating wind power in power systems. The mitigation of wind power impacts include more flexible operational methods, incentivising flexibility in other generating plants, increasing interconnection to neighbouring regions, and application of demand-side flexibility. Electricity storage is still not as cost effective in larger power systems as other means of flexibility, but is already seeing initial applications in places with limited transmission. Electricity markets, with cross-border trade of intra-day and balancing resources and emerging ancillary services markets, are seen as promising for future large penetration levels for wind power. (orig.)

  5. Multivariate statistical analysis software technologies for astrophysical research involving large data bases

    Science.gov (United States)

    Djorgovski, S. George

    1994-01-01

    We developed a package to process and analyze the data from the digital version of the Second Palomar Sky Survey. This system, called SKICAT, incorporates the latest in machine learning and expert systems software technology, in order to classify the detected objects objectively and uniformly, and facilitate handling of the enormous data sets from digital sky surveys and other sources. The system provides a powerful, integrated environment for the manipulation and scientific investigation of catalogs from virtually any source. It serves three principal functions: image catalog construction, catalog management, and catalog analysis. Through use of the GID3* Decision Tree artificial induction software, SKICAT automates the process of classifying objects within CCD and digitized plate images. To exploit these catalogs, the system also provides tools to merge them into a large, complete database which may be easily queried and modified when new data or better methods of calibrating or classifying become available. The most innovative feature of SKICAT is the facility it provides to experiment with and apply the latest in machine learning technology to the tasks of catalog construction and analysis. SKICAT provides a unique environment for implementing these tools for any number of future scientific purposes. Initial scientific verification and performance tests have been made using galaxy counts and measurements of galaxy clustering from small subsets of the survey data, and a search for very high redshift quasars. All of the tests were successful, and produced new and interesting scientific results. Attachments to this report give detailed accounts of the technical aspects for multivariate statistical analysis of small and moderate-size data sets, called STATPROG. The package was tested extensively on a number of real scientific applications, and has produced real, published results.

  6. Multivariate Statistical Analysis Software Technologies for Astrophysical Research Involving Large Data Bases

    Science.gov (United States)

    Djorgovski, S. G.

    1994-01-01

    We developed a package to process and analyze the data from the digital version of the Second Palomar Sky Survey. This system, called SKICAT, incorporates the latest in machine learning and expert systems software technology, in order to classify the detected objects objectively and uniformly, and facilitate handling of the enormous data sets from digital sky surveys and other sources. The system provides a powerful, integrated environment for the manipulation and scientific investigation of catalogs from virtually any source. It serves three principal functions: image catalog construction, catalog management, and catalog analysis. Through use of the GID3* Decision Tree artificial induction software, SKICAT automates the process of classifying objects within CCD and digitized plate images. To exploit these catalogs, the system also provides tools to merge them into a large, complex database which may be easily queried and modified when new data or better methods of calibrating or classifying become available. The most innovative feature of SKICAT is the facility it provides to experiment with and apply the latest in machine learning technology to the tasks of catalog construction and analysis. SKICAT provides a unique environment for implementing these tools for any number of future scientific purposes. Initial scientific verification and performance tests have been made using galaxy counts and measurements of galaxy clustering from small subsets of the survey data, and a search for very high redshift quasars. All of the tests were successful and produced new and interesting scientific results. Attachments to this report give detailed accounts of the technical aspects of the SKICAT system, and of some of the scientific results achieved to date. We also developed a user-friendly package for multivariate statistical analysis of small and moderate-size data sets, called STATPROG. The package was tested extensively on a number of real scientific applications and has

  7. Rotation sequence to report humerothoracic kinematics during 3D motion involving large horizontal component: application to the tennis forehand drive.

    Science.gov (United States)

    Creveaux, Thomas; Sevrez, Violaine; Dumas, Raphaël; Chèze, Laurence; Rogowski, Isabelle

    2018-03-01

    The aim of this study was to examine the respective aptitudes of three rotation sequences (Y t X f 'Y h '', Z t X f 'Y h '', and X t Z f 'Y h '') to effectively describe the orientation of the humerus relative to the thorax during a movement involving a large horizontal abduction/adduction component: the tennis forehand drive. An optoelectronic system was used to record the movements of eight elite male players, each performing ten forehand drives. The occurrences of gimbal lock, phase angle discontinuity and incoherency in the time course of the three angles defining humerothoracic rotation were examined for each rotation sequence. Our results demonstrated that no single sequence effectively describes humerothoracic motion without discontinuities throughout the forehand motion. The humerothoracic joint angles can nevertheless be described without singularities when considering the backswing/forward-swing and the follow-through phases separately. Our findings stress that the sequence choice may have implications for the report and interpretation of 3D joint kinematics during large shoulder range of motion. Consequently, the use of Euler/Cardan angles to represent 3D orientation of the humerothoracic joint in sport tasks requires the evaluation of the rotation sequence regarding singularity occurrence before analysing the kinematic data, especially when the task involves a large shoulder range of motion in the horizontal plane.

  8. An approach to industrial water conservation--a case study involving two large manufacturing companies based in Australia.

    Science.gov (United States)

    Agana, Bernard A; Reeve, Darrell; Orbell, John D

    2013-01-15

    This study presents the application of an integrated water management strategy at two large Australian manufacturing companies that are contrasting in terms of their respective products. The integrated strategy, consisting of water audit, pinch analysis and membrane process application, was deployed in series to systematically identify water conservation opportunities. Initially, a water audit was deployed to completely characterize all water streams found at each production site. This led to the development of a water balance diagram which, together with water test results, served as a basis for subsequent enquiry. After the water audit, commercially available water pinch software was utilized to identify possible water reuse opportunities, some of which were subsequently implemented on site. Finally, utilizing a laboratory-scale test rig, membrane processes such as UF, NF and RO were evaluated for their suitability to treat the various wastewater streams. The membranes tested generally showed good contaminant rejection rates, slow flux decline rates, low energy usage and were well suited for treatment of specific wastewater streams. The synergy between the various components of this strategy has the potential to reduce substantial amounts of Citywater consumption and wastewater discharge across a diverse range of large manufacturing companies. Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

  9. Feasibility of an energy conversion system in Canada involving large-scale integrated hydrogen production using solid fuels

    International Nuclear Information System (INIS)

    Gnanapragasam, Nirmal V.; Reddy, Bale V.; Rosen, Marc A.

    2010-01-01

    A large-scale hydrogen production system is proposed using solid fuels and designed to increase the sustainability of alternative energy forms in Canada, and the technical and economic aspects of the system within the Canadian energy market are examined. The work investigates the feasibility and constraints in implementing such a system within the energy infrastructure of Canada. The proposed multi-conversion and single-function system produces hydrogen in large quantities using energy from solid fuels such as coal, tar sands, biomass, municipal solid waste (MSW) and agricultural/forest/industrial residue. The proposed system involves significant technology integration, with various energy conversion processes (such as gasification, chemical looping combustion, anaerobic digestion, combustion power cycles-electrolysis and solar-thermal converters) interconnected to increase the utilization of solid fuels as much as feasible within cost, environmental and other constraints. The analysis involves quantitative and qualitative assessments based on (i) energy resources availability and demand for hydrogen, (ii) commercial viability of primary energy conversion technologies, (iii) academia, industry and government participation, (iv) sustainability and (v) economics. An illustrative example provides an initial road map for implementing such a system. (author)

  10. Statistical process control charts for attribute data involving very large sample sizes: a review of problems and solutions.

    Science.gov (United States)

    Mohammed, Mohammed A; Panesar, Jagdeep S; Laney, David B; Wilson, Richard

    2013-04-01

    The use of statistical process control (SPC) charts in healthcare is increasing. The primary purpose of SPC is to distinguish between common-cause variation which is attributable to the underlying process, and special-cause variation which is extrinsic to the underlying process. This is important because improvement under common-cause variation requires action on the process, whereas special-cause variation merits an investigation to first find the cause. Nonetheless, when dealing with attribute or count data (eg, number of emergency admissions) involving very large sample sizes, traditional SPC charts often produce tight control limits with most of the data points appearing outside the control limits. This can give a false impression of common and special-cause variation, and potentially misguide the user into taking the wrong actions. Given the growing availability of large datasets from routinely collected databases in healthcare, there is a need to present a review of this problem (which arises because traditional attribute charts only consider within-subgroup variation) and its solutions (which consider within and between-subgroup variation), which involve the use of the well-established measurements chart and the more recently developed attribute charts based on Laney's innovative approach. We close by making some suggestions for practice.

  11. Saturation transfer EPR (ST-EPR) for dating biocarbonates containing large amount of Mn2+: separation of SO3- and CO2- lines and geochronology of Brazilian fish fossil

    International Nuclear Information System (INIS)

    Sastry, M.D.; Andrade, M.B.; Watanabe, Shigueo

    2003-01-01

    A method using saturation transfer EPR (ST-EPR) is shown to be feasible for detecting EPR signal of radiation-induced defects in biocarbonates containing large amount of Mn 2+ . The ST-EPR measurements conducted at room temperature on fish fossil of Brazilian origin, enabled the identification of CO 2 - and SO 3 - radical ions, by partially suppressing the intense signal from Mn 2+ when the signal are detected 90 deg. out of phase with magnetic field modulating signal and at high microwave power (50 mW). Using these signals the age of fish fossil is estimated to be (36±5) Ma

  12. Involvement of herbal medicine as a cause of mesenteric phlebosclerosis: results from a large-scale nationwide survey.

    Science.gov (United States)

    Shimizu, Seiji; Kobayashi, Taku; Tomioka, Hideo; Ohtsu, Kensei; Matsui, Toshiyuki; Hibi, Toshifumi

    2017-03-01

    Mesenteric phlebosclerosis (MP) is a rare disease characterized by venous calcification extending from the colonic wall to the mesentery, with chronic ischemic changes from venous return impairment in the intestine. It is an idiopathic disease, but increasing attention has been paid to the potential involvement of herbal medicine, or Kampo, in its etiology. Until now, there were scattered case reports, but no large-scale studies have been conducted to unravel the clinical characteristics and etiology of the disease. A nationwide survey was conducted using questionnaires to assess possible etiology (particularly the involvement of herbal medicine), clinical manifestations, disease course, and treatment of MP. Data from 222 patients were collected. Among the 169 patients (76.1 %), whose history of herbal medicine was obtained, 147 (87.0 %) used herbal medicines. The use of herbal medicines containing sanshishi (gardenia fruit, Gardenia jasminoides Ellis) was reported in 119 out of 147 patients (81.0 %). Therefore, the use of herbal medicine containing sanshishi was confirmed in 70.4 % of 169 patients whose history of herbal medicine was obtained. The duration of sanshishi use ranged from 3 to 51 years (mean 13.6 years). Patients who discontinued sanshishi showed a better outcome compared with those who continued it. The use of herbal medicine containing sanshishi is associated with the etiology of MP. Although it may not be the causative factor, it is necessary for gastroenterologists to be aware of the potential risk of herbal medicine containing sanshishi for the development of MP.

  13. A rapid and practical strategy for the determination of platinum, palladium, ruthenium, rhodium, iridium and gold in large amounts of ultrabasic rock by inductively coupled plasma optical emission spectrometry combined with ultrasound extraction

    Science.gov (United States)

    Zhang, Gai; Tian, Min

    2015-04-01

    This proposed method regulated the determination of platinum, palladium, ruthenium, rhodium, iridium and gold in platinum-group ores by nickel sulfide fire assay—inductively coupled plasma optical emission spectrometry (ICP-OES) combined with ultrasound extraction for the first time. The quantitative limits were 0.013-0.023μg/g. The samples were fused to separate the platinum-group elements from matrix. The nickel sulfide button was then dissolved with hydrochloric acid and the insoluble platinum-group sulfide residue was dissolved with aqua regia by ultrasound bath and finally determined by ICP-OES. The proposed method has been applied into the determination of platinum-group element and gold in large amounts of ultrabasic rocks from the Great Dyke of Zimbabwe.

  14. Assisted reproduction involving gestational surrogacy: an analysis of the medical, psychosocial and legal issues: experience from a large surrogacy program.

    Science.gov (United States)

    Dar, Shir; Lazer, Tal; Swanson, Sonja; Silverman, Jan; Wasser, Cindy; Moskovtsev, Sergey I; Sojecki, Agata; Librach, Clifford L

    2015-02-01

    What are the medical, psychosocial and legal aspects of gestational surrogacy (GS), including pregnancy outcomes and complications, in a large series? Meticulous multidisciplinary teamwork, involving medical, legal and psychosocial input for both the intended parent(s) (IP) and the gestational carrier (GC), is critical to achieve a successful GS program. Small case series have described pregnancy rates of 17-50% for GS. There are no large case series and the medical, legal and psychological aspects of GS have not been addressed in most of these studies. To our knowledge, this is the largest reported GS case series. A retrospective cohort study was performed. Data were collected from 333 consecutive GC cycles between 1998 and 2012. There were 178 pregnancies achieved out of 333 stimulation cycles, including fresh and frozen transfers. The indications for a GC were divided into two groups. Those who have 'failed to carry', included women with recurrent implantation failure (RIF), recurrent pregnancy loss (RPL) and previous poor pregnancy outcome (n = 96; 132 cycles, pregnancy rate 50.0%). The second group consisted of those who 'cannot carry' including those with severe Asherman's syndrome, uterine malformations/uterine agenesis and maternal medical diseases (n = 108, 139 cycles, pregnancy rate 54.0%). A third group, of same-sex male couples and single men, were analyzed separately (n = 52, 62 cycles, pregnancy rate 59.7%). In 49.2% of cycles, autologous oocytes were used and 50.8% of cycles involved donor oocytes. The 'failed to carry' group consisted of 96 patients who underwent 132 cycles at a mean age of 40.3 years. There were 66 pregnancies (50.0%) with 17 miscarriages (25.8%) and 46 confirmed births (34.8%). The 'cannot carry pregnancy' group consisted of 108 patients who underwent 139 cycles at a mean age of 35.9 years. There were 75 pregnancies (54.0%) with 15 miscarriages (20.0%) and 56 confirmed births (40.3%). The pregnancy, miscarriage and live birth

  15. Functional and Aesthetic Outcome of Reconstruction of Large Oro-Facial Defects Involving the Lip after Tumor Resection

    International Nuclear Information System (INIS)

    Denewer, A.D.; Setie, A.E.; Hussein, O.A.; Aly, O.F.

    2006-01-01

    Background: Squamous cell carcinoma of the head and neck is a challenging disease to both surgeons and radiation oncologists due to proximity of many important anatomical structures. Surgery could be curative as these cancers usually metastasize very late by blood stream. Aim of the Work: This work addresses the oncologic, functional and aesthetic factors affecting reconstruction of large orofacial defects involving the lip following tumor resection. Patients and Methods: The study reviews the surgical outcome of one hundred and twelve patients with invasive tumors at. or extending to, the lip(s). treated at the Mansoura University - Surgical Oncology Department, from January 2000 to January 2005. Tumor stage were T 2 (43), T 3 (56) and T 4 (13). Nodal state was N 0 in 80, N 1 in 29 and N 2 in three cases. AJCC stage grouping was II (T 2 N 0 ) in 33 patients. stage III (T 3 N 0 orT 1-3 N 1 ) in 64 cases and stage IV (T 4 due to bone erosion or N 2 ) in 15 cases. The technique used for lip reconstruction was unilateral or bilateral myocutaneous depressor anguli oris flap (MCDAOF) for isolated lip defect (n=63). Bilateral myocutaneous depressor anguli oris (MCDAOF) plus local cervical rotational flap chin defects (n=3). pectorals major myocutaneous pedicled flap for cheek defects involving the lip together with a tongue flap for mucosal reconstruction (n=35). sternocleidomastoid clavicular myo-osseous flap for concomitant mandibular defects (n=] 2). Results: esthetic and functional results are evaluated regarding appearance, oral incompetence, disabling microstomia and eating difficulties. depressor anguli oris reconstruction allowed functioning static and dynamic oral function in all cases in contrast to the Pectorals major flap. there were 18 cases of oral incompetence (46.1%), nine cases of speech difficulty (23%) and five patients with poor cosmetic appearance within the second group total flap loss was not encountered, Partial nap loss affected thirteen

  16. The use of public participation and economic appraisal for public involvement in large-scale hydropower projects: Case study of the Nam Theun 2 Hydropower Project

    International Nuclear Information System (INIS)

    Mirumachi, Naho; Torriti, Jacopo

    2012-01-01

    Gaining public acceptance is one of the main issues with large-scale low-carbon projects such as hydropower development. It has been recommended by the World Commission on Dams that to gain public acceptance, public involvement is necessary in the decision-making process (). As financially-significant actors in the planning and implementation of large-scale hydropower projects in developing country contexts, the paper examines the ways in which public involvement may be influenced by international financial institutions. Using the case study of the Nam Theun 2 Hydropower Project in Laos, the paper analyses how public involvement facilitated by the Asian Development Bank had a bearing on procedural and distributional justice. The paper analyses the extent of public participation and the assessment of full social and environmental costs of the project in the Cost-Benefit Analysis conducted during the project appraisal stage. It is argued that while efforts were made to involve the public, there were several factors that influenced procedural and distributional justice: the late contribution of the Asian Development Bank in the project appraisal stage; and the issue of non-market values and discount rate to calculate the full social and environmental costs. - Highlights: ► Public acceptance in large-scale hydropower projects is examined. ► Both procedural and distributional justice are important for public acceptance. ► International Financial Institutions can influence the level of public involvement. ► Public involvement benefits consideration of non-market values and discount rates.

  17. The Management Challenge: Handling Exams Involving Large Quantities of Students, on and off Campus--A Design Concept

    Science.gov (United States)

    Larsson, Ken

    2014-01-01

    This paper looks at the process of managing large numbers of exams efficiently and secure with the use of a dedicated IT support. The system integrates regulations on different levels, from national to local, (even down to departments) and ensures that the rules are employed in all stages of handling the exams. The system has a proven record of…

  18. How senior entomologists can be involved in the annual meeting: organization and the coming together of a large event

    Science.gov (United States)

    The Annual Meeting for the Entomological Society of America is a large event where planning is started at the end of the previous years’ meeting. The President of the Society named the Program Committee Co-Chairs for Entomology 2017 at the 2015 Annual Meeting, so that they could handle the duties o...

  19. Bone marrow involvement in diffuse large B-cell lymphoma: correlation between FDG-PET uptake and type of cellular infiltrate

    International Nuclear Information System (INIS)

    Paone, Gaetano; Itti, Emmanuel; Lin, Chieh; Meignan, Michel; Haioun, Corinne; Dupuis, Jehan; Gaulard, Philippe

    2009-01-01

    To assess, in patients with diffuse large B-cell lymphoma (DLBCL), whether the low sensitivity of 18 F-fluorodeoxyglucose positron emission tomography (FDG-PET) for bone marrow assessment may be explained by histological characteristics of the cellular infiltrate. From a prospective cohort of 110 patients with newly diagnosed aggressive lymphoma, 21 patients with DLBCL had bone marrow involvement. Pretherapeutic FDG-PET images were interpreted visually and semiquantitatively, then correlated with the type of cellular infiltrate and known prognostic factors. Of these 21 patients, 7 (33%) had lymphoid infiltrates with a prominent component of large transformed lymphoid cells (concordant bone marrow involvement, CBMI) and 14 (67%) had lymphoid infiltrates composed of small cells (discordant bone marrow involvement, DBMI). Only 10 patients (48%) had abnormal bone marrow FDG uptake, 6 of the 7 with CBMI and 4 of the 14 with DBMI. Therefore, FDG-PET positivity in the bone marrow was significantly associated with CBMI, while FDG-PET negativity was associated with DBMI (Fisher's exact test, p=0.024). There were no significant differences in gender, age and overall survival between patients with CBMI and DBMI, while the international prognostic index was significantly higher in patients with CBMI. Our study suggests that in patients with DLBCL with bone marrow involvement bone marrow FDG uptake depends on two types of infiltrate, comprising small (DBMI) or large (CBMI) cells. This may explain the apparent low sensitivity of FDG-PET previously reported for detecting bone marrow involvement. (orig.)

  20. The Effects of Group Relaxation Training/Large Muscle Exercise, and Parental Involvement on Attention to Task, Impulsivity, and Locus of Control among Hyperactive Boys.

    Science.gov (United States)

    Porter, Sally S.; Omizo, Michael M.

    1984-01-01

    The study examined the effects of group relaxation training/large muscle exercise and parental involvement on attention to task, impulsivity, and locus of control among 34 hyperactive boys. Following treatment both experimental groups recorded significantly higher attention to task, lower impulsivity, and lower locus of control scores. (Author/CL)

  1. Concordant bone marrow involvement of diffuse large B-cell lymphoma represents a distinct clinical and biological entity in the era of immunotherapy

    DEFF Research Database (Denmark)

    Yao, Zhilei; Deng, Lijuan; Xu-Monette, Z Y

    2018-01-01

    In diffuse large B-cell lymphoma (DLBCL), the clinical and biological significance of concordant and discordant bone marrow (BM) involvement have not been well investigated. We evaluated 712 de novo DLBCL patients with front-line rituximab-containing treatment, including 263 patients with positiv...

  2. Investigation of deep inelastic scattering processes involving large p$_{t}$ direct photons in the final state

    CERN Multimedia

    2002-01-01

    This experiment will investigate various aspects of photon-parton scattering and will be performed in the H2 beam of the SPS North Area with high intensity hadron beams up to 350 GeV/c. \\\\\\\\ a) The directly produced photon yield in deep inelastic hadron-hadron collisions. Large p$_{t}$ direct photons from hadronic interactions are presumably a result of a simple annihilation process of quarks and antiquarks or of a QCD-Compton process. The relative contribution of the two processes can be studied by using various incident beam projectiles $\\pi^{+}, \\pi^{-}, p$ and in the future $\\bar{p}$. \\\\\\\\b) The correlations between directly produced photons and their accompanying hadronic jets. We will examine events with a large p$_{t}$ direct photon for away-side jets. If jets are recognised their properties will be investigated. Differences between a gluon and a quark jet may become observable by comparing reactions where valence quark annihilations (away-side jet originates from a gluon) dominate over the QDC-Compton...

  3. The PHD Domain of Np95 (mUHRF1) Is Involved in Large-Scale Reorganization of Pericentromeric Heterochromatin

    Science.gov (United States)

    Papait, Roberto; Pistore, Christian; Grazini, Ursula; Babbio, Federica; Cogliati, Sara; Pecoraro, Daniela; Brino, Laurent; Morand, Anne-Laure; Dechampesme, Anne-Marie; Spada, Fabio; Leonhardt, Heinrich; McBlane, Fraser; Oudet, Pierre

    2008-01-01

    Heterochromatic chromosomal regions undergo large-scale reorganization and progressively aggregate, forming chromocenters. These are dynamic structures that rapidly adapt to various stimuli that influence gene expression patterns, cell cycle progression, and differentiation. Np95-ICBP90 (m- and h-UHRF1) is a histone-binding protein expressed only in proliferating cells. During pericentromeric heterochromatin (PH) replication, Np95 specifically relocalizes to chromocenters where it highly concentrates in the replication factories that correspond to less compacted DNA. Np95 recruits HDAC and DNMT1 to PH and depletion of Np95 impairs PH replication. Here we show that Np95 causes large-scale modifications of chromocenters independently from the H3:K9 and H4:K20 trimethylation pathways, from the expression levels of HP1, from DNA methylation and from the cell cycle. The PHD domain is essential to induce this effect. The PHD domain is also required in vitro to increase access of a restriction enzyme to DNA packaged into nucleosomal arrays. We propose that the PHD domain of Np95-ICBP90 contributes to the opening and/or stabilization of dense chromocenter structures to support the recruitment of modifying enzymes, like HDAC and DNMT1, required for the replication and formation of PH. PMID:18508923

  4. Differences in passenger car and large truck involved crash frequencies at urban signalized intersections: an exploratory analysis.

    Science.gov (United States)

    Dong, Chunjiao; Clarke, David B; Richards, Stephen H; Huang, Baoshan

    2014-01-01

    The influence of intersection features on safety has been examined extensively because intersections experience a relatively large proportion of motor vehicle conflicts and crashes. Although there are distinct differences between passenger cars and large trucks-size, operating characteristics, dimensions, and weight-modeling crash counts across vehicle types is rarely addressed. This paper develops and presents a multivariate regression model of crash frequencies by collision vehicle type using crash data for urban signalized intersections in Tennessee. In addition, the performance of univariate Poisson-lognormal (UVPLN), multivariate Poisson (MVP), and multivariate Poisson-lognormal (MVPLN) regression models in establishing the relationship between crashes, traffic factors, and geometric design of roadway intersections is investigated. Bayesian methods are used to estimate the unknown parameters of these models. The evaluation results suggest that the MVPLN model possesses most of the desirable statistical properties in developing the relationships. Compared to the UVPLN and MVP models, the MVPLN model better identifies significant factors and predicts crash frequencies. The findings suggest that traffic volume, truck percentage, lighting condition, and intersection angle significantly affect intersection safety. Important differences in car, car-truck, and truck crash frequencies with respect to various risk factors were found to exist between models. The paper provides some new or more comprehensive observations that have not been covered in previous studies. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. Giant-cell arteritis. Concordance study between aortic CT angiography and FDG-PET/CT in detection of large-vessel involvement

    International Nuclear Information System (INIS)

    Boysson, Hubert de; Dumont, Anael; Boutemy, Jonathan; Maigne, Gwenola; Martin Silva, Nicolas; Sultan, Audrey; Bienvenu, Boris; Aouba, Achille; Liozon, Eric; Ly, Kim Heang; Lambert, Marc; Aide, Nicolas; Manrique, Alain

    2017-01-01

    The purpose of our study was to assess the concordance of aortic CT angiography (CTA) and FDG-PET/CT in the detection of large-vessel involvement at diagnosis in patients with giant-cell arteritis (GCA). We created a multicenter cohort of patients with GCA diagnosed between 2010 and 2015, and who underwent both FDG-PET/CT and aortic CTA before or in the first ten days following treatment introduction. Eight vascular segments were studied on each procedure. We calculated concordance between both imaging techniques in a per-patient and a per-segment analysis, using Cohen's kappa concordance index. We included 28 patients (21/7 women/men, median age 67 [56-82]). Nineteen patients had large-vessel involvement on PET/CT and 18 of these patients also presented positive findings on CTA. In a per-segment analysis, a median of 5 [1-7] and 3 [1-6] vascular territories were involved on positive PET/CT and CTA, respectively (p = 0.03). In qualitative analysis, i.e., positivity of the procedure suggesting a large-vessel involvement, the concordance rate between both procedures was 0.85 [0.64-1]. In quantitative analysis, i.e., per-segment analysis in both procedures, the global concordance rate was 0.64 [0.54-0.75]. Using FDG-PET/CT as a reference, CTA showed excellent sensitivity (95%) and specificity (100%) in a per-patient analysis. In a per-segment analysis, sensitivity and specificity were 61% and 97.9%, respectively. CTA and FDG-PET/CT were both able to detect large-vessel involvement in GCA with comparable results in a per-patient analysis. However, PET/CT showed higher performance in a per-segment analysis, especially in the detection of inflammation of the aorta's branches. (orig.)

  6. Giant-cell arteritis. Concordance study between aortic CT angiography and FDG-PET/CT in detection of large-vessel involvement

    Energy Technology Data Exchange (ETDEWEB)

    Boysson, Hubert de; Dumont, Anael; Boutemy, Jonathan; Maigne, Gwenola; Martin Silva, Nicolas; Sultan, Audrey; Bienvenu, Boris; Aouba, Achille [Caen University Hospital, Department of Internal Medicine, Caen (France); Liozon, Eric; Ly, Kim Heang [Limoges University Hospital, Department of Internal Medicine, Limoges (France); Lambert, Marc [Lille University Hospital, Department of Internal Medicine, Lille (France); Aide, Nicolas [Caen University Hospital, Department of Nuclear Medicine, Caen (France); INSERM U1086 ' ' ANTICIPE' ' , Francois Baclesse Cancer Centre, Caen (France); Manrique, Alain [Caen University Hospital, Department of Nuclear Medicine, Caen (France); Normandy University, Caen (France)

    2017-12-15

    The purpose of our study was to assess the concordance of aortic CT angiography (CTA) and FDG-PET/CT in the detection of large-vessel involvement at diagnosis in patients with giant-cell arteritis (GCA). We created a multicenter cohort of patients with GCA diagnosed between 2010 and 2015, and who underwent both FDG-PET/CT and aortic CTA before or in the first ten days following treatment introduction. Eight vascular segments were studied on each procedure. We calculated concordance between both imaging techniques in a per-patient and a per-segment analysis, using Cohen's kappa concordance index. We included 28 patients (21/7 women/men, median age 67 [56-82]). Nineteen patients had large-vessel involvement on PET/CT and 18 of these patients also presented positive findings on CTA. In a per-segment analysis, a median of 5 [1-7] and 3 [1-6] vascular territories were involved on positive PET/CT and CTA, respectively (p = 0.03). In qualitative analysis, i.e., positivity of the procedure suggesting a large-vessel involvement, the concordance rate between both procedures was 0.85 [0.64-1]. In quantitative analysis, i.e., per-segment analysis in both procedures, the global concordance rate was 0.64 [0.54-0.75]. Using FDG-PET/CT as a reference, CTA showed excellent sensitivity (95%) and specificity (100%) in a per-patient analysis. In a per-segment analysis, sensitivity and specificity were 61% and 97.9%, respectively. CTA and FDG-PET/CT were both able to detect large-vessel involvement in GCA with comparable results in a per-patient analysis. However, PET/CT showed higher performance in a per-segment analysis, especially in the detection of inflammation of the aorta's branches. (orig.)

  7. An International Collaborative Study of Outcome and Prognostic Factors in Patients with Secondary CNS Involvement By Diffuse Large B-Cell Lymphoma

    DEFF Research Database (Denmark)

    El-Galaly, Tarec Christoffer; Cheah, Chan Yoon; Bendtsen, Mette Dahl

    2016-01-01

    ) determine prognostic factors after SCNS.Patients and methods: We performed a retrospective study of patients diagnosed with SCNS during or after frontline immunochemotherapy (R-CHOP or equivalently effective regimens). SCNS was defined as new involvement of the CNS (parenchymal, leptomeningeal, and/or eye......Background: Secondary CNS involvement (SCNS) is a detrimental complication seen in ~5% of patients with diffuse large B-cell lymphoma (DLBCL) treated with modern immunochemotherapy. Data from older series report short survival following SCNS, typically lt;6 months. However, data in patients...

  8. Retrospective review of adverse incidents involving passengers seated in wheeled mobility devices while traveling in large accessible transit vehicles.

    Science.gov (United States)

    Frost, Karen L; Bertocci, Gina

    2010-04-01

    Characterize wheeled mobility device (WhMD) adverse incidents on large accessible transit vehicles (LATVs) based on vehicle motion, WhMD activity during incident, incident scenario and injury. Retrospective records review. WhMD passengers traveling on LATVs while remaining seated in their. Adverse incidents characterized based on vehicle motion, WhMD activity during incident, and incident scenario. Injury characterized based on outcome, medical attention sought, vehicle activity, WhMD activity and incident scenario. 115 WhMD-related incident reports for years 2000-2005 were analyzed. Most incidents occurred when the LATV was stopped (73.9%), during ingress/egress (42.6%), and at the securement station (33.9%) when the LATV was moving. The combination of WhMD tipping and passenger falling (43.4%) occurred most frequently, and was 1.8 times more likely to occur during ingress/egress than at the securement station. One-third (33.6%) of all incidents resulted in injury, and injuries were equally distributed between ingress/egress (43.6%) and at the securement station (43.6%). WhMD users have a greater chance of incurring injury during ingress/egress than during transit. Research is needed to objectively assess real world transportation experiences of WhMD passengers, and to assess the adequacy of existing federal legislation/guidelines for accessible ramps used in public transportation. Copyright 2009 IPEM. Published by Elsevier Ltd. All rights reserved.

  9. Applying the Plan-Do-Study-Act (PDSA) approach to a large pragmatic study involving safety net clinics.

    Science.gov (United States)

    Coury, Jennifer; Schneider, Jennifer L; Rivelli, Jennifer S; Petrik, Amanda F; Seibel, Evelyn; D'Agostini, Brieshon; Taplin, Stephen H; Green, Beverly B; Coronado, Gloria D

    2017-06-19

    The Plan-Do-Study-Act (PDSA) cycle is a commonly used improvement process in health care settings, although its documented use in pragmatic clinical research is rare. A recent pragmatic clinical research study, called the Strategies and Opportunities to STOP Colon Cancer in Priority Populations (STOP CRC), used this process to optimize the research implementation of an automated colon cancer screening outreach program in intervention clinics. We describe the process of using this PDSA approach, the selection of PDSA topics by clinic leaders, and project leaders' reactions to using PDSA in pragmatic research. STOP CRC is a cluster-randomized pragmatic study that aims to test the effectiveness of a direct-mail fecal immunochemical testing (FIT) program involving eight Federally Qualified Health Centers in Oregon and California. We and a practice improvement specialist trained in the PDSA process delivered structured presentations to leaders of these centers; the presentations addressed how to apply the PDSA process to improve implementation of a mailed outreach program offering colorectal cancer screening through FIT tests. Center leaders submitted PDSA plans and delivered reports via webinar at quarterly meetings of the project's advisory board. Project staff conducted one-on-one, 45-min interviews with project leads from each health center to assess the reaction to and value of the PDSA process in supporting the implementation of STOP CRC. Clinic-selected PDSA activities included refining the intervention staffing model, improving outreach materials, and changing workflow steps. Common benefits of using PDSA cycles in pragmatic research were that it provided a structure for staff to focus on improving the program and it allowed staff to test the change they wanted to see. A commonly reported challenge was measuring the success of the PDSA process with the available electronic medical record tools. Understanding how the PDSA process can be applied to pragmatic

  10. One Patient, Two Uncommon B-Cell Neoplasms: Solitary Plasmacytoma following Complete Remission from Intravascular Large B-Cell Lymphoma Involving Central Nervous System

    Directory of Open Access Journals (Sweden)

    Joycelyn Lee

    2014-01-01

    Full Text Available Second lymphoid neoplasms are an uncommon but recognized feature of non-Hodgkin’s lymphomas, putatively arising secondary to common genetic or environmental risk factors. Previous limited evaluations of clonal relatedness between successive mature B-cell malignancies have yielded mixed results. We describe the case of a man with intravascular large B-cell lymphoma involving the central nervous system who went into clinical remission following immunochemotherapy and brain radiation, only to relapse 2 years later with a plasmacytoma of bone causing cauda equina syndrome. The plasmacytoma stained strongly for the cell cycle regulator cyclin D1 on immunohistochemistry, while the original intravascular large cell lymphoma was negative, a disparity providing no support for clonal identity between the 2 neoplasms. Continued efforts atcataloging and evaluating unique associations of B-cell malignancies are critical to improving understanding of overarching disease biology in B-cell malignancies.

  11. Social Work Involvement in Advance Care Planning: Findings from a Large Survey of Social Workers in Hospice and Palliative Care Settings.

    Science.gov (United States)

    Stein, Gary L; Cagle, John G; Christ, Grace H

    2017-03-01

    Few data are available describing the involvement and activities of social workers in advance care planning (ACP). We sought to provide data about (1) social worker involvement and leadership in ACP conversations with patients and families; and (2) the extent of functions and activities when these discussions occur. We conducted a large web-based survey of social workers employed in hospice, palliative care, and related settings to explore their role, participation, and self-rated competency in facilitating ACP discussions. Respondents were recruited through the Social Work Hospice and Palliative Care Network and the National Hospice and Palliative Care Organization. Descriptive analyses were conducted on the full sample of respondents (N = 641) and a subsample of clinical social workers (N = 456). Responses were analyzed to explore differences in ACP involvement by practice setting. Most clinical social workers (96%) reported that social workers in their department are conducting ACP discussions with patients/families. Majorities also participate in, and lead, ACP discussions (69% and 60%, respectively). Most respondents report that social workers are responsible for educating patients/families about ACP options (80%) and are the team members responsible for documenting ACP (68%). Compared with other settings, oncology and inpatient palliative care social workers were less likely to be responsible for ensuring that patients/families are informed of ACP options and documenting ACP preferences. Social workers are prominently involved in facilitating, leading, and documenting ACP discussions. Policy-makers, administrators, and providers should incorporate the vital contributions of social work professionals in policies and programs supporting ACP.

  12. Clinical response to a lomustine/cytarabine-based chemotherapy protocol in a case of canine large granular lymphocyte T-cell lymphoma with spinal involvement

    Directory of Open Access Journals (Sweden)

    Elisabetta Treggiari

    2018-05-01

    Full Text Available A 7-year-old, female neutered cross-breed dog was referred to our institution with a history of progressive hind limb weakness, which then progressed to paraplegia. An MRI of the spine revealed severe meningeal infiltrate consistent with lymphoma involvement, located at the level of L2-L7 with concurrent lymph node enlargement and abnormal bone marrow. Abdominal ultrasonography also identified changes in the spleen and confirmed enlargement of the lumbar aortic lymph node. Cytology of lymph nodes and spleen confirmed a high-grade lymphoma with features of a large granular lymphocyte (LGL variant; PCR for antigen receptor re-arrangements (PARR was positive for a clonal T-cell receptor rearrangement. The dog was started on a chemotherapy protocol with lomustine and cytarabine incorporation and had a rapid improvement in neurological status. Chemotherapy was continued until relapse and rescue treatment used at that time. The dog was euthanased at the time of recurrence of neurological signs, 195 days since medical treatment was started. This case report suggests that combination chemotherapy may be of use when treating LGL lymphoma with spinal involvement and survival time may potentially exceed 6 months.

  13. A Reasoned Action Model of Male Client Involvement in Commercial Sex Work in Kibera, A Large Informal Settlement in Nairobi, Kenya.

    Science.gov (United States)

    Roth, Eric Abella; Ngugi, Elizabeth; Benoit, Cecilia; Jansson, Mikael; Hallgrimsdottir, Helga

    2014-01-01

    Male clients of female sex workers (FSWs) are epidemiologically important because they can form bridge groups linking high- and low-risk subpopulations. However, because male clients are hard to locate, they are not frequently studied. Recent research emphasizes searching for high-risk behavior groups in locales where new sexual partnerships form and the threat of HIV transmission is high. Sub-Saharan Africa public drinking venues satisfy these criteria. Accordingly, this study developed and implemented a rapid assessment methodology to survey men in bars throughout the large informal settlement of Kibera, Nairobi, Kenya, with the goal of delineating cultural and economic rationales associated with male participation in commercial sex. The study sample consisted of 220 male patrons of 110 bars located throughout Kibera's 11 communities. Logistic regression analysis incorporating a modified Reasoned Action Model indicated that a social norm condoning commercial sex among male peers and the cultural belief that men should practice sex before marriage support commercial sex involvement. Conversely, lacking money to drink and/or pay for sexual services were barriers to male commercial sex involvement. Results are interpreted in light of possible harm reduction programs focusing on FSWs' male clients.

  14. Possible Role of GADD45γ Methylation in Diffuse Large B-Cell Lymphoma: Does It Affect the Progression and Tissue Involvement?

    Directory of Open Access Journals (Sweden)

    İkbal Cansu Barış

    2015-12-01

    Full Text Available INTRODUCTION: Diffuse large B-cell lymphoma (DLBCL is the most common type of non-Hodgkin lymphoma among adults and is characterized by heterogeneous clinical, immunophenotypic, and genetic features. Different mechanisms deregulating cell cycle and apoptosis play a role in the pathogenesis of DLBCL. Growth arrest DNA damage-inducible 45 (GADD45γ is an important gene family involved in these mechanisms. The aims of this study are to determine the frequency of GADD45γ methylation, to evaluate the correlation between GADD45γ methylation and protein expression, and to investigate the relation between methylation status and clinicopathologic parameters in DLBCL tissues and reactive lymphoid node tissues from patients with reactive lymphoid hyperplasia. METHODS: Thirty-six tissue samples of DLBCL and 40 nonmalignant reactive lymphoid node tissues were analyzed in this study. Methylation-sensitive high-resolution melting analysis was used for the determination of GADD45γ methylation status. The GADD45γ protein expression was determined by immunohistochemistry. RESULTS: GADD45γ methylation was frequent (50.0% in DLBCL. It was also significantly higher in advanced-stage tumors compared with early-stage (p=0.041. In contrast, unmethylated GADD45γ was associated with nodal involvement as the primary anatomical site (p=0.040. DISCUSSION AND CONCLUSION: The results of this study show that, in contrast to solid tumors, the frequency of GADD45γ methylation is higher and this epigenetic alteration of GADD45γ may be associated with progression in DLBCL. In addition, nodal involvement is more likely to be present in patients with unmethylated GADD45γ.

  15. De novo characterization of the spleen transcriptome of the large yellow croaker (Pseudosciaena crocea) and analysis of the immune relevant genes and pathways involved in the antiviral response

    KAUST Repository

    Mu, Yinnan

    2014-05-12

    The large yellow croaker (Pseudosciaena crocea) is an economically important marine fish in China. To understand the molecular basis for antiviral defense in this species, we used Illumia paired-end sequencing to characterize the spleen transcriptome of polyriboinosinic:polyribocytidylic acid [poly(I:C)]-induced large yellow croakers. The library produced 56,355,728 reads and assembled into 108,237 contigs. As a result, 15,192 unigenes were found from this transcriptome. Gene ontology analysis showed that 4,759 genes were involved in three major functional categories: biological process, cellular component, and molecular function. We further ascertained that numerous consensus sequences were homologous to known immune-relevant genes. Kyoto Encyclopedia of Genes and Genomes orthology mapping annotated 5,389 unigenes and identified numerous immune-relevant pathways. These immune-relevant genes and pathways revealed major antiviral immunity effectors, including but not limited to: pattern recognition receptors, adaptors and signal transducers, the interferons and interferon-stimulated genes, inflammatory cytokines and receptors, complement components, and B-cell and T-cell antigen activation molecules. Moreover, the partial genes of Toll-like receptor signaling pathway, RIG-I-like receptors signaling pathway, Janus kinase-Signal Transducer and Activator of Transcription (JAK-STAT) signaling pathway, and T-cell receptor (TCR) signaling pathway were found to be changed after poly(I:C) induction by real-time polymerase chain reaction (PCR) analysis, suggesting that these signaling pathways may be regulated by poly(I:C), a viral mimic. Overall, the antivirus-related genes and signaling pathways that were identified in response to poly(I:C) challenge provide valuable leads for further investigation of the antiviral defense mechanism in the large yellow croaker. © 2014 Mu et al.

  16. De novo characterization of the spleen transcriptome of the large yellow croaker (Pseudosciaena crocea and analysis of the immune relevant genes and pathways involved in the antiviral response.

    Directory of Open Access Journals (Sweden)

    Yinnan Mu

    Full Text Available The large yellow croaker (Pseudosciaena crocea is an economically important marine fish in China. To understand the molecular basis for antiviral defense in this species, we used Illumia paired-end sequencing to characterize the spleen transcriptome of polyriboinosinic:polyribocytidylic acid [poly(I:C]-induced large yellow croakers. The library produced 56,355,728 reads and assembled into 108,237 contigs. As a result, 15,192 unigenes were found from this transcriptome. Gene ontology analysis showed that 4,759 genes were involved in three major functional categories: biological process, cellular component, and molecular function. We further ascertained that numerous consensus sequences were homologous to known immune-relevant genes. Kyoto Encyclopedia of Genes and Genomes orthology mapping annotated 5,389 unigenes and identified numerous immune-relevant pathways. These immune-relevant genes and pathways revealed major antiviral immunity effectors, including but not limited to: pattern recognition receptors, adaptors and signal transducers, the interferons and interferon-stimulated genes, inflammatory cytokines and receptors, complement components, and B-cell and T-cell antigen activation molecules. Moreover, the partial genes of Toll-like receptor signaling pathway, RIG-I-like receptors signaling pathway, Janus kinase-Signal Transducer and Activator of Transcription (JAK-STAT signaling pathway, and T-cell receptor (TCR signaling pathway were found to be changed after poly(I:C induction by real-time polymerase chain reaction (PCR analysis, suggesting that these signaling pathways may be regulated by poly(I:C, a viral mimic. Overall, the antivirus-related genes and signaling pathways that were identified in response to poly(I:C challenge provide valuable leads for further investigation of the antiviral defense mechanism in the large yellow croaker.

  17. De novo characterization of the spleen transcriptome of the large yellow croaker (Pseudosciaena crocea) and analysis of the immune relevant genes and pathways involved in the antiviral response

    KAUST Repository

    Mu, Yinnan; Li, Mingyu; Ding, Feng; Ding, Yang; Ao, Jingqun; Hu, Songnian; Chen, Xinhua

    2014-01-01

    The large yellow croaker (Pseudosciaena crocea) is an economically important marine fish in China. To understand the molecular basis for antiviral defense in this species, we used Illumia paired-end sequencing to characterize the spleen transcriptome of polyriboinosinic:polyribocytidylic acid [poly(I:C)]-induced large yellow croakers. The library produced 56,355,728 reads and assembled into 108,237 contigs. As a result, 15,192 unigenes were found from this transcriptome. Gene ontology analysis showed that 4,759 genes were involved in three major functional categories: biological process, cellular component, and molecular function. We further ascertained that numerous consensus sequences were homologous to known immune-relevant genes. Kyoto Encyclopedia of Genes and Genomes orthology mapping annotated 5,389 unigenes and identified numerous immune-relevant pathways. These immune-relevant genes and pathways revealed major antiviral immunity effectors, including but not limited to: pattern recognition receptors, adaptors and signal transducers, the interferons and interferon-stimulated genes, inflammatory cytokines and receptors, complement components, and B-cell and T-cell antigen activation molecules. Moreover, the partial genes of Toll-like receptor signaling pathway, RIG-I-like receptors signaling pathway, Janus kinase-Signal Transducer and Activator of Transcription (JAK-STAT) signaling pathway, and T-cell receptor (TCR) signaling pathway were found to be changed after poly(I:C) induction by real-time polymerase chain reaction (PCR) analysis, suggesting that these signaling pathways may be regulated by poly(I:C), a viral mimic. Overall, the antivirus-related genes and signaling pathways that were identified in response to poly(I:C) challenge provide valuable leads for further investigation of the antiviral defense mechanism in the large yellow croaker. © 2014 Mu et al.

  18. Visualization of Large Amount of Spectra in Virtual Observatory Environment

    Czech Academy of Sciences Publication Activity Database

    Šaloun, P.; Andrešič, D.; Škoda, Petr; Zelinka, I.

    2014-01-01

    Roč. 11, č. 6 (2014), s. 613-620 ISSN 1476-8186 Institutional support: RVO:67985815 Keywords : SPLAT-VO * virtual observatory * spectra Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  19. Nuclear operator. Liability amounts and financial security limits

    International Nuclear Information System (INIS)

    2015-07-01

    This paper gives, for numerous countries involved (or would be involved) in nuclear activities, financial information on the liability amount imposed on the operator, the amounts provided from public funds beyond the Operator's Liability Amount, to be made available by the State in whose territory the nuclear installation of the liable operator is situated, and the public funds contributed jointly by all the States parties to the BSC or CSC according to a pre-determined formula

  20. Presence of a large β(1-3)glucan linked to chitin at the Saccharomyces cerevisiae mother-bud neck suggests involvement in localized growth control.

    Science.gov (United States)

    Cabib, Enrico; Blanco, Noelia; Arroyo, Javier

    2012-04-01

    Previous results suggested that the chitin ring present at the yeast mother-bud neck, which is linked specifically to the nonreducing ends of β(1-3)glucan, may help to suppress cell wall growth at the neck by competing with β(1-6)glucan and thereby with mannoproteins for their attachment to the same sites. Here we explored whether the linkage of chitin to β(1-3)glucan may also prevent the remodeling of this polysaccharide that would be necessary for cell wall growth. By a novel mild procedure, β(1-3)glucan was isolated from cell walls, solubilized by carboxymethylation, and fractionated by size exclusion chromatography, giving rise to a very high-molecular-weight peak and to highly polydisperse material. The latter material, soluble in alkali, may correspond to glucan being remodeled, whereas the large-size fraction would be the final cross-linked structural product. In fact, the β(1-3)glucan of buds, where growth occurs, is solubilized by alkali. A gas1 mutant with an expected defect in glucan elongation showed a large increase in the polydisperse fraction. By a procedure involving sodium hydroxide treatment, carboxymethylation, fractionation by affinity chromatography on wheat germ agglutinin-agarose, and fractionation by size chromatography on Sephacryl columns, it was shown that the β(1-3)glucan attached to chitin consists mostly of high-molecular-weight material. Therefore, it appears that linkage to chitin results in a polysaccharide that cannot be further remodeled and does not contribute to growth at the neck. In the course of these experiments, the new finding was made that part of the chitin forms a noncovalent complex with β(1-3)glucan.

  1. Uterine, but not ovarian, female reproductive organ involvement at presentation by diffuse large B-cell lymphoma is associated with poor outcomes and a high frequency of secondary CNS involvement

    DEFF Research Database (Denmark)

    El-Galaly, Tarec Christoffer; Cheah, Chan Y; Hutchings, Martin

    2016-01-01

    progression-free survival and overall survival compared to those without reproductive organ involvement, whereas ovarian DLBCL was not predictive of outcome. Secondary central nervous system (CNS) involvement (SCNS) occurred in 7/17 (41%) women with uterine DLBCL (two patients with concomitant ovarian DLBCL...

  2. Additional Survival Benefit of Involved-Lesion Radiation Therapy After R-CHOP Chemotherapy in Limited Stage Diffuse Large B-Cell Lymphoma

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Jeanny [Department of Radiation Oncology, Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Il Han, E-mail: ihkim@snu.ac.kr [Department of Radiation Oncology, Seoul National University College of Medicine, Seoul (Korea, Republic of); Cancer Research Institute, Seoul National University College of Medicine, Seoul (Korea, Republic of); Institute of Radiation Medicine, Medical Research Center, Seoul National University, Seoul (Korea, Republic of); Kim, Byoung Hyuck [Department of Radiation Oncology, Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Tae Min; Heo, Dae Seog [Department of Internal Medicine, Seoul National University Hospital, Seoul (Korea, Republic of)

    2015-05-01

    Purpose: The purpose of this study was to evaluate the role of involved-lesion radiation therapy (ILRT) after rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy in limited stage diffuse large B-cell lymphoma (DLBCL) by comparing outcomes of R-CHOP therapy alone with R-CHOP followed by ILRT. Methods and Materials: We identified 198 patients treated with R-CHOP (median, 6 cycles) for pathologically confirmed DLBCL of limited stage from July 2004 to December 2012. Clinical characteristics of these patients were 33% with stage I and 66.7% with stage II; 79.8% were in the low or low-intermediate risk group; 13.6% had B symptoms; 29.8% had bulky tumors (≥7 cm); and 75.3% underwent ≥6 cycles of R-CHOP therapy. RT was given to 43 patients (21.7%) using ILRT technique, which included the prechemotherapy tumor volume with a median margin of 2 cm (median RT dose: 36 Gy). Results: After a median follow-up of 40 months, 3-year progression-free survival (PFS) and overall survival (OS) were 85.8% and 88.9%, respectively. Multivariate analysis showed ≥6 cycles of R-CHOP (PFS, P=.004; OS, P=.004) and ILRT (PFS, P=.021; OS, P=.014) were favorable prognosticators of PFS and OS. A bulky tumor (P=.027) and response to R-CHOP (P=.012) were also found to be independent factors of OS. In subgroup analysis, the effect of ILRT was prominent in patients with a bulky tumor (PFS, P=.014; OS, P=.030) or an elevated level of serum lactate dehydrogenase (LDH; PFS, P=.004; OS, P=.012). Conclusions: Our results suggest that ILRT after R-CHOP therapy improves PFS and OS in patients with limited stage DLBCL, especially in those with bulky disease or an elevated serum LDH level.

  3. Additional survival benefit of involved-lesion radiation therapy after R-CHOP chemotherapy in limited stage diffuse large B-cell lymphoma.

    Science.gov (United States)

    Kwon, Jeanny; Kim, Il Han; Kim, Byoung Hyuck; Kim, Tae Min; Heo, Dae Seog

    2015-05-01

    The purpose of this study was to evaluate the role of involved-lesion radiation therapy (ILRT) after rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy in limited stage diffuse large B-cell lymphoma (DLBCL) by comparing outcomes of R-CHOP therapy alone with R-CHOP followed by ILRT. We identified 198 patients treated with R-CHOP (median, 6 cycles) for pathologically confirmed DLBCL of limited stage from July 2004 to December 2012. Clinical characteristics of these patients were 33% with stage I and 66.7% with stage II; 79.8% were in the low or low-intermediate risk group; 13.6% had B symptoms; 29.8% had bulky tumors (≥ 7 cm); and 75.3% underwent ≥ 6 cycles of R-CHOP therapy. RT was given to 43 patients (21.7%) using ILRT technique, which included the prechemotherapy tumor volume with a median margin of 2 cm (median RT dose: 36 Gy). After a median follow-up of 40 months, 3-year progression-free survival (PFS) and overall survival (OS) were 85.8% and 88.9%, respectively. Multivariate analysis showed ≥ 6 cycles of R-CHOP (PFS, P=.004; OS, P=.004) and ILRT (PFS, P=.021; OS, P=.014) were favorable prognosticators of PFS and OS. A bulky tumor (P=.027) and response to R-CHOP (P=.012) were also found to be independent factors of OS. In subgroup analysis, the effect of ILRT was prominent in patients with a bulky tumor (PFS, P=.014; OS, P=.030) or an elevated level of serum lactate dehydrogenase (LDH; PFS, P=.004; OS, P=.012). Our results suggest that ILRT after R-CHOP therapy improves PFS and OS in patients with limited stage DLBCL, especially in those with bulky disease or an elevated serum LDH level. Copyright © 2015. Published by Elsevier Inc.

  4. Large fractions of CO2-fixing microorganisms in pristine limestone aquifers appear to be involved in the oxidation of reduced sulfur and nitrogen compounds

    Science.gov (United States)

    Herrmann, Martina; Rusznyák, Anna; Akob, Denise M.; Schulze, Isabel; Opitz, Sebastian; Totsche, Kai Uwe; Küsel, Kirsten

    2015-01-01

    The traditional view of the dependency of subsurface environments on surface-derived allochthonous carbon inputs is challenged by increasing evidence for the role of lithoautotrophy in aquifer carbon flow. We linked information on autotrophy (Calvin-Benson-Bassham cycle) with that from total microbial community analysis in groundwater at two superimposed—upper and lower—limestone groundwater reservoirs (aquifers). Quantitative PCR revealed that up to 17% of the microbial population had the genetic potential to fix CO2 via the Calvin cycle, with abundances of cbbM and cbbL genes, encoding RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) forms I and II, ranging from 1.14 × 103 to 6 × 106 genes liter−1 over a 2-year period. The structure of the active microbial communities based on 16S rRNA transcripts differed between the two aquifers, with a larger fraction of heterotrophic, facultative anaerobic, soil-related groups in the oxygen-deficient upper aquifer. Most identified CO2-assimilating phylogenetic groups appeared to be involved in the oxidation of sulfur or nitrogen compounds and harbored both RubisCO forms I and II, allowing efficient CO2 fixation in environments with strong oxygen and CO2 fluctuations. The genera Sulfuricellaand Nitrosomonas were represented by read fractions of up to 78 and 33%, respectively, within the cbbM and cbbL transcript pool and accounted for 5.6 and 3.8% of 16S rRNA sequence reads, respectively, in the lower aquifer. Our results indicate that a large fraction of bacteria in pristine limestone aquifers has the genetic potential for autotrophic CO2 fixation, with energy most likely provided by the oxidation of reduced sulfur and nitrogen compounds.

  5. An International Collaborative Study of Outcome and Prognostic Factors in Patients with Secondary CNS Involvement By Diffuse Large B-Cell Lymphoma

    DEFF Research Database (Denmark)

    El-Galaly, Tarec Christoffer; Cheah, Chan Yoon; Bendtsen, Mette Dahl

    2016-01-01

    that develop SCNS following primary therapy that contains a rituximab-based-regimen as well as the impact of more intensified treatment for SCNS are limited.Aims: The aims of this study were to i) describe the natural history of SCNS in a large cohort of patients treated with immunochemotherapy, and ii......' Hospital, London). Clinico-pathologic and treatment characteristics at the time of SCNS were collected from medical records.Results: In total, 281 patients with SCNS diagnosed between 2001 and 2016 were included. Median age at SCNS was 64 (range 20-93) years and male:female ratio was 1.3. SCNS occurred...... Myers Squib: Research Funding; NanoString Technologies: Research Funding; F Hoffmann-La Roche: Research Funding; Millennium Takeda: Research Funding; Seattle Genetics: Research Funding. Sehn: roche/genentech: Consultancy, Honoraria; amgen: Consultancy, Honoraria; seattle genetics: Consultancy, Honoraria...

  6. Attitudes towards people with mental illness among psychiatrists, psychiatric nurses, involved family members and the general population in a large city in Guangzhou, China.

    Science.gov (United States)

    Sun, Bin; Fan, Ni; Nie, Sha; Zhang, Minglin; Huang, Xini; He, Hongbo; Rosenheck, Robert A

    2014-01-01

    Stigma towards people with mental illness is believed to be widespread in low and middle income countries. This study assessed the attitudes towards people with mental illness among psychiatrists, psychiatric nurses, involved family members of patients in a psychiatric facility and the general public using a standard 43-item survey (N = 535). Exploratory factor analysis identified four distinctive attitudes which were then compared using Analysis of Covariance (ANCOVA) among the four groups, all with ties to the largest psychiatric facility in Guangzhou, China, adjusting for sociodemographic differences. Four uncorrelated factors expressed preferences for 1) community-based treatment, social integration and a biopsychosocial model of causation, 2) direct personal relationships with people with mental illness, 3) a lack of fear and positive views of personal interactions with people with mental illness, 4) disbelief in superstitious explanations of mental illness. Statistically significant differences favored community-based treatment and biopsychosocial causation (factor 1) among professional groups (psychiatrists and nurses) as compared with family members and the general public (p problems of their relatives and support in their care.

  7. A large scale survey reveals that chromosomal copy-number alterations significantly affect gene modules involved in cancer initiation and progression

    Directory of Open Access Journals (Sweden)

    Cigudosa Juan C

    2011-05-01

    Full Text Available Abstract Background Recent observations point towards the existence of a large number of neighborhoods composed of functionally-related gene modules that lie together in the genome. This local component in the distribution of the functionality across chromosomes is probably affecting the own chromosomal architecture by limiting the possibilities in which genes can be arranged and distributed across the genome. As a direct consequence of this fact it is therefore presumable that diseases such as cancer, harboring DNA copy number alterations (CNAs, will have a symptomatology strongly dependent on modules of functionally-related genes rather than on a unique "important" gene. Methods We carried out a systematic analysis of more than 140,000 observations of CNAs in cancers and searched by enrichments in gene functional modules associated to high frequencies of loss or gains. Results The analysis of CNAs in cancers clearly demonstrates the existence of a significant pattern of loss of gene modules functionally related to cancer initiation and progression along with the amplification of modules of genes related to unspecific defense against xenobiotics (probably chemotherapeutical agents. With the extension of this analysis to an Array-CGH dataset (glioblastomas from The Cancer Genome Atlas we demonstrate the validity of this approach to investigate the functional impact of CNAs. Conclusions The presented results indicate promising clinical and therapeutic implications. Our findings also directly point out to the necessity of adopting a function-centric, rather a gene-centric, view in the understanding of phenotypes or diseases harboring CNAs.

  8. High-sensitivity direct analysis of aflatoxins in peanuts and cereal matrices by ultra-performance liquid chromatography with fluorescence detection involving a large volume flow cell.

    Science.gov (United States)

    Oulkar, Dasharath; Goon, Arnab; Dhanshetty, Manisha; Khan, Zareen; Satav, Sagar; Banerjee, Kaushik

    2018-04-03

    This paper reports a sensitive and cost effective method of analysis for aflatoxins B1, B2, G1 and G2. The sample preparation method was primarily optimised in peanuts, followed by its validation in a range of peanut-processed products and cereal (rice, corn, millets) matrices. Peanut slurry [12.5 g peanut + 12.5 mL water] was extracted with methanol: water (8:2, 100 mL), cleaned through an immunoaffinity column and thereafter measured directly by ultra-performance liquid chromatography-fluorescence (UPLC-FLD) detection, within a chromatographic runtime of 5 minutes. The use of a large volume flow cell in the FLD nullified the requirement of any post-column derivatisation and provided the lowest ever reported limits of quantification of 0.025 for B1 and G1 and 0.01 μg/kg for B2 and G2. The single laboratory validation of the method provided acceptable selectivity, linearity, recovery and precision for reliable quantifications in all the test matrices as well as demonstrated compliance with the EC 401/2006 guidelines for analytical quality control of aflatoxins in foodstuffs.

  9. SMILE: experimental results of the WP4 PTS large scale test performed on a component in terms of cracked cylinder involving warm pre-stress

    International Nuclear Information System (INIS)

    Kerkhof, K.; Bezdikian, G.; Moinereau, D.; Dahl, A; Wadier, Y.; Gilles, P.; Keim, E.; Chapuliot, S.; Taylor, N.; Lidbury, D.; Sharples, J.; Budden, P.; Siegele, D.; Nagel, G.; Bass, R.; Emond, D.

    2005-01-01

    The Reactor Pressure Vessel (RPV) is an essential component, which is liable to limit the lifetime duration of PWR plants. The assessment of defects in RPV subjected to pressurized thermal shock (PTS) transients made at an European level generally does not necessarily consider the beneficial effect of the load history (Warm Pre-stress, WPS). The SMILE project - Structural Margin Improvements in aged embrittled RPV with Load history Effects-aims to give sufficient elements to demonstrate, to model and to validate the beneficial WPS effect. It also aims to harmonize the different approaches in the national codes and standards regarding the inclusion of the WPS effect in a RPV structural integrity assessment. The project includes significant experimental work on WPS type experiments with C(T) specimens and a PTS type transient experiment on a large component. This paper deals with the results of the PTS type transient experiment on a component-like specimen subjected to WPS- loading, the so called Validation Test, carried out within the framework of work package WP4. The test specimen consists of a cylindrical thick walled specimen with a thickness of 40 mm and an outer diameter of 160 mm, provided with an internal fully circumferential crack with a depth of about 15 mm. The specified load path type is Load-Cool-Unload-Fracture (LCUF). No crack initiation occurred during cooling (thermal shock loading) although the loading path crossed the fracture toughness curve in the transition region. The benefit of the WPS-effect by final re-loading up to fracture in the lower shelf region, was shown clearly. The corresponding fracture load during reloading in the lower shelf region was significantly higher than the crack initiation values of the original material in the lower shelf region. The post test fractographic evaluation showed that the fracture mode was predominantly cleavage fracture also with some secondary cracks emanating from major crack. (authors)

  10. Genome-wide association analysis for heat tolerance at flowering detected a large set of genes involved in adaptation to thermal and other stresses.

    Directory of Open Access Journals (Sweden)

    Tanguy Lafarge

    Full Text Available Fertilization sensitivity to heat in rice is a major issue within climate change scenarios in the tropics. A panel of 167 indica landraces and improved varieties was phenotyped for spikelet sterility (SPKST under 38°C during anthesis and for several secondary traits potentially affecting panicle micro-climate and thus the fertilization process. The panel was genotyped with an average density of one marker per 29 kb using genotyping by sequencing. Genome-wide association analyses (GWAS were conducted using three methods based on single marker regression, haplotype regression and simultaneous fitting of all markers, respectively. Fourteen loci significantly associated with SPKST under at least two GWAS methods were detected. A large number of associations was also detected for the secondary traits. Analysis of co-localization of SPKST associated loci with QTLs detected in progenies of bi-parental crosses reported in the literature allowed to narrow -down the position of eight of those QTLs, including the most documented one, qHTSF4.1. Gene families underlying loci associated with SPKST corresponded to functions ranging from sensing abiotic stresses and regulating plant response, such as wall-associated kinases and heat shock proteins, to cell division and gametophyte development. Analysis of diversity at the vicinity of loci associated with SPKST within the rice three thousand genomes, revealed widespread distribution of the favourable alleles across O. sativa genetic groups. However, few accessions assembled the favourable alleles at all loci. Effective donors included the heat tolerant variety N22 and some Indian and Taiwanese varieties. These results provide a basis for breeding for heat tolerance during anthesis and for functional validation of major loci governing this trait.

  11. 46 CFR 308.403 - Insured amounts.

    Science.gov (United States)

    2010-10-01

    ... total amount of war risk insurance obtainable from companies authorized to do an insurance business in a... MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Builder's Risk Insurance § 308.403 Insured amounts. (a) Prelaunching period. The amount insured during...

  12. 13 CFR 400.202 - Loan amount.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Loan amount. 400.202 Section 400.202 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.202 Loan amount. (a) The aggregate amount of loan principal guaranteed...

  13. 13 CFR 500.202 - Loan amount.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Loan amount. 500.202 Section 500.202 Business Credit and Assistance EMERGENCY OIL AND GAS GUARANTEED LOAN BOARD EMERGENCY OIL AND GAS GUARANTEED LOAN PROGRAM Oil and Gas Guaranteed Loans § 500.202 Loan amount. The aggregate amount of loan...

  14. 45 CFR 32.8 - Amounts withheld.

    Science.gov (United States)

    2010-10-01

    ...) of this section, or (ii) An amount equal to 25% of the debtor's disposable pay less the amount(s... first pay day after the employer receives the order. However, if the first pay day is within 10 days after receipt of the order, the employer may begin deductions on the second pay day. (k) An employer may...

  15. 31 CFR 235.5 - Reclamation amounts.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Reclamation amounts. 235.5 Section 235.5 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE... ON DESIGNATED DEPOSITARIES § 235.5 Reclamation amounts. Amounts received by way of reclamation on...

  16. 29 CFR 4.141 - General criteria for measuring amount.

    Science.gov (United States)

    2010-07-01

    ... Government for such work under his contract or may even agree to pay the Government in return for the right... formal advertising, in arriving at the aggregate amount involved, there must be included all property and... single advertisement for bids if the procurement were being effected by formal advertising. Therefore, if...

  17. 24 CFR 201.10 - Loan amounts.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Loan amounts. 201.10 Section 201.10... MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES TITLE I PROPERTY IMPROVEMENT AND MANUFACTURED HOME LOANS Loan and Note Provisions § 201.10 Loan amounts. (a) Property...

  18. Left ventricular rigid body rotation in a diffuse large B-cell lymphoma patient with cardiac involvement: A case from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study.

    Science.gov (United States)

    Földeák, Dóra; Kalapos, Anita; Domsik, Péter; Sinkó, Mária; Szeleczki, Nóra; Bagdi, Enikő; Krenács, László; Forster, Tamás; Borbényi, Zita; Nemes, Attila

    2017-02-01

    Secondary myocardial involvement by diffuse large B-cell lymphoma is a rare occurrence. Left ventricular (LV) twist is considered an essential part of LV function. In normal circumstances LV twist results from the movement of two orthogonally oriented muscular bands of a helical myocardial structure with consequent clockwise rotation of the base and counterclockwise rotation of the apex. Three-dimensional (3D) speckle-tracking echocardiography (3DSTE) has been found to be feasible for non-invasive 3D quantification of LV wall motion and rotational mechanics. The present report aimed to assess LV twisting motion in a patient with diffuse large B-cell lymphoma with positron emission tomography/computer tomography-proven cardiac involvement by 3DSTE. During 3DSTE, reduction in some segmental radial, longitudinal, circumferential, area and 3D LV strains were found. Apical and basal LV rotations were found to be in the same counterclockwise direction, confirming near absence of LV twist - so-called rigid body rotation. Copyright © 2016 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.

  19. Trace amount analysis using spark mass spectrometry

    International Nuclear Information System (INIS)

    Stefani, Rene

    1975-01-01

    Characteristics of spark mass spectrometers (ion source, properties of the ion beam, ion optics, and performance) and their use in qualitative and quantitative analysis are described. This technique is very interesting for the semi-quantitative analysis of trace amounts, down to 10 -8 atoms. Examples of applications such as the analysis of high purity materials and non-conducting mineral samples, and determination of carbon and gas trace amounts are presented. (50 references) [fr

  20. Standardized uptake value for (18)F-fluorodeoxyglucose is correlated with a high International Prognostic Index and the presence of extranodal involvement in patients with diffuse large B-cell lymphoma.

    Science.gov (United States)

    Akkas, B E; Vural, G U

    2014-01-01

    The aim of this study was to evaluate whether the maximum standardized uptake value (SUVmax) of (18)F-fluorodeoxyglucose (FDG) correlates with the International Prognostic Index (IPI) and the presence of extranodal involvement in patients with Diffuse Large B-Cell Lymphoma (DLBCL). 77 patients (age: 57.2±18.5, 40F, 37M) with DLBCL who underwent FDG PET/CT for initial staging were included. SUVmax of the predominant lesions were compared to Ann Arbor stage, IPI scores, the presence of extranodal involvement and the number extranodal sites. PET/CT detected nodal (n:25) and extranodal involvement (n:52) in all the patients. In 27 patients, extranodal disease could only be detected by PET. SUVmax of the predominant lesion in patients with extranodal disease was significantly higher than that of the patients who had only nodal disease (25±12 vs. 15.3±10 respectively, p=0.001). SUVmax significantly correlated with IPI scores; the average SUVmax was significantly correlated with the IPI: Mean SUVmax of the predominant lesion was 13.9±9.5 in patients with low risk (IPI=0-1), 14.2±8.8 in low-intermediate risk group (IPI=2) whereas 26.6±9.5 in high-intermediate risk group (IPI=3) and 25±13.6 in high risk group patients (IPI=4-5) (p=0.002). SUVmax was not correlated with clinical stage, the number of extranodal sites and serum LDH levels. FDG uptake correlates with IPI and the presence of extranodal involvement in DLBCL. PET is a powerful method to detect extranodal disease in DLBCL. The correlation of SUVmax with these prognostic factors may highlight the importance of pretreatment FDG uptake as a metabolic marker of poor prognosis for patients with DLBCL. Copyright © 2013 Elsevier España, S.L. and SEMNIM. All rights reserved.

  1. Unusual amount of (-)-mesquitol from the heartwood of Prosopis juliflora.

    Science.gov (United States)

    Sirmah, Peter; Dumarçay, Stéphane; Masson, Eric; Gérardin, Philippe

    2009-01-01

    A large amount of flavonoid has been extracted and isolated from the heartwood of Prosopis juliflora, an exogenous wood species of Kenya. Structural and physicochemical elucidation based on FTIR, (1)H and (13)C NMR, GC-MS and HPLC analysis clearly demonstrated the presence of (-)-mesquitol as the sole compound without any noticeable impurities. The product was able to slow down oxidation of methyl linoleate induced by AIBN. The important amount and high purity of (-)-mesquitol present in the acetonic extract of P. juliflora could therefore be of valuable interest as a potential source of antioxidants from a renewable origin.

  2. The effect of amount and tangibility of endowment and certainty of recipients on selfishness in a modified dictator game.

    Science.gov (United States)

    Chang, Shao-Chuan; Lin, Li-Yun; Horng, Ruey-Yun; Wang, Yau-De

    2014-06-01

    Taiwanese college students (N = 101) participated in the study to examine the effects of the amount of an endowment, the tangibility of an endowment, and the certainty of the recipient on selfishness in a modified dictator game. Results showed that dictators were more selfish when allocating tangible (money) than less tangible (honor credits) endowments. Selfishness was higher when large amounts of money were involved. The certainty of the recipient was manipulated by whether the recipient was chosen and announced before or after the decision. Unexpectedly, participants were more self-interested in the certain-recipient condition than in the uncertain-recipient condition. In the honor condition, the amount of an endowment and the certainty of the recipient did not affect participants' allocations.

  3. Parental involvement

    Directory of Open Access Journals (Sweden)

    Ezra S Simon

    2005-01-01

    Full Text Available Parent-Teacher Associations and other community groups can play a significant role in helping to establish and run refugee schools; their involvement can also help refugee adults adjust to their changed circumstances.

  4. 29 CFR 4219.14 - Amount of liability for 20-year-limitation amounts.

    Science.gov (United States)

    2010-07-01

    ... amount equal to the present value of all initial withdrawal liability payments for which the employer was not liable pursuant to section 4219(c)(1)(B) of ERISA. The present value of such payments shall be... 29 Labor 9 2010-07-01 2010-07-01 false Amount of liability for 20-year-limitation amounts. 4219.14...

  5. The Arabidopsis gene DIG6 encodes a large 60S subunit nuclear export GTPase 1 that is involved in ribosome biogenesis and affects multiple auxin-regulated development processes

    KAUST Repository

    Zhao, Huayan

    2015-08-13

    The circularly permuted GTPase large subunit GTPase 1 (LSG1) is involved in the maturation step of the 60S ribosome and is essential for cell viability in yeast. Here, an Arabidopsis mutant dig6 (drought inhibited growth of lateral roots) was isolated. The mutant exhibited multiple auxin-related phenotypes, which included reduced lateral root number, altered leaf veins, and shorter roots. Genetic mapping combined with next-generation DNA sequencing identified that the mutation occurred in AtLSG1-2. This gene was highly expressed in regions of auxin accumulation. Ribosome profiling revealed that a loss of function of AtLSG1-2 led to decreased levels of monosomes, further demonstrating its role in ribosome biogenesis. Quantitative proteomics showed that the expression of certain proteins involved in ribosome biogenesis was differentially regulated, indicating that ribosome biogenesis processes were impaired in the mutant. Further investigations showed that an AtLSG1-2 deficiency caused the alteration of auxin distribution, response, and transport in plants. It is concluded that AtLSG1-2 is integral to ribosome biogenesis, consequently affecting auxin homeostasis and plant development.

  6. The Arabidopsis gene DIG6 encodes a large 60S subunit nuclear export GTPase 1 that is involved in ribosome biogenesis and affects multiple auxin-regulated development processes

    KAUST Repository

    Zhao, Huayan; Lü , Shiyou; Li, Ruixi; Chen, Tao; Zhang, Huoming; Cui, Peng; Ding, Feng; Liu, Pei; Wang, Guangchao; Xia, Yiji; Running, Mark P.; Xiong, Liming

    2015-01-01

    The circularly permuted GTPase large subunit GTPase 1 (LSG1) is involved in the maturation step of the 60S ribosome and is essential for cell viability in yeast. Here, an Arabidopsis mutant dig6 (drought inhibited growth of lateral roots) was isolated. The mutant exhibited multiple auxin-related phenotypes, which included reduced lateral root number, altered leaf veins, and shorter roots. Genetic mapping combined with next-generation DNA sequencing identified that the mutation occurred in AtLSG1-2. This gene was highly expressed in regions of auxin accumulation. Ribosome profiling revealed that a loss of function of AtLSG1-2 led to decreased levels of monosomes, further demonstrating its role in ribosome biogenesis. Quantitative proteomics showed that the expression of certain proteins involved in ribosome biogenesis was differentially regulated, indicating that ribosome biogenesis processes were impaired in the mutant. Further investigations showed that an AtLSG1-2 deficiency caused the alteration of auxin distribution, response, and transport in plants. It is concluded that AtLSG1-2 is integral to ribosome biogenesis, consequently affecting auxin homeostasis and plant development.

  7. How restrained eaters perceive the amount they eat.

    Science.gov (United States)

    Jansen, A

    1996-09-01

    The cognitive model of binge eating states that it is the awareness of a broken diet that disinhibits the restrained eater. It is, according to that model, the perception of having overeaten that triggers disinhibited eating. However, although the perception of the amount eaten plays a central role in cognitive restraint theory, it has never directly been tested how restrained subjects perceive the amount of food they eat. In the present studies, participants were given ad libitum access to large amounts of palatable food and both their perception of the amount eaten and their estimated caloric intake were compared with the amount they actually ate. The restrained participants in these studies ate more than the unrestrained participants. In the first and second studies, the restrained participants consumed 571 and 372 'forbidden' calories respectively, without having the feeling that they had eaten very much, let alone too much. Moreover in both studies, the restrained eaters underestimated their caloric intake, whereas unrestrained eaters estimated their caloric intake quite well. The potential implications of the present findings for the cognitive restraint model are discussed.

  8. 13 CFR 120.930 - Amount.

    Science.gov (United States)

    2010-01-01

    ... percent of total Project cost plus 100 percent of eligible administrative costs. For good cause shown, SBA... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Amount. 120.930 Section 120.930 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Development Company Loan...

  9. 33 CFR 135.203 - Amount required.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Amount required. 135.203 Section 135.203 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND...

  10. Physician Fee Schedule National Payment Amount File

    Data.gov (United States)

    U.S. Department of Health & Human Services — The significant size of the Physician Fee Schedule Payment Amount File-National requires that database programs (e.g., Access, dBase, FoxPro, etc.) be used to read...

  11. Mechanisms of membrane protein insertion into liposomes during reconstitution procedures involving the use of detergents. 1. Solubilization of large unilamellar liposomes (Prepared by reverse-phase evaporation) by Triton X-100 octyl glucoside, and sodium cholate

    International Nuclear Information System (INIS)

    Paternostre, M.T.; Roux, M.; Rigaud, J.L.

    1988-01-01

    The mechanisms governing the solubilization by Triton X-100, octyl glucoside, and sodium cholate of large unilamellar liposomes prepared by reverse-phase evaporation were investigated. The solubilization process is described by the three-stage model previously proposed for the detergents. In stage I, detergent monomers are incorporated into the phospholipid bilayers until they saturate the liposomes. At this point, i.e., stage II, mixed phospholipid-detergent micelles begin to form. By stage III, the lamellar to micellar transition is complete and all the phospholipids are present as mixed micelles. The turbidity of liposome preparations was systematically measured as a function of the amount of detergent added for a wide range of phospholipid concentrations. The results allowed a quantitative determination of the effective detergent to lipid molar ratios in the saturated liposomes. The monomer concentrations of the three detergents in the aqueous phase were also determined at the lamellar to micellar transitions. These transitions were also investigated by 31 P NMR spectroscopy, and complete agreement was found with turbidity measurements. Freeze-fracture electron microscopy and permeability studies in the sublytic range of detergent concentrations indicated that during stage I of solubilization detergent partitioning between the aqueous phase and the lipid bilayer greatly affects the basic permeability of the liposomes without significantly changing the morphology of the preparations. A rough approximation of the partition coefficients was derived from the turbidity and permeability data. It is concluded that when performed systematically, turbidity measurements constitute a very convenient and powerful technique for the quantitative study of the liposome solubilization process by detergents

  12. Radiculography with reduced amounts of contrast medium

    International Nuclear Information System (INIS)

    Signorini, E.; Caputo, N.; Chiurulla, C.; Ciorba, E.; Pelliccioli, G.P.; Cianciulli, E.

    1984-01-01

    Because of the frequency and seriousness of side effects observed after radiculography, due to, among the other things, the amount of contrast medium, the authors describe a method that gives diagnostically satisfactory results using a low dose of contrast and a tangent-beam technique. Among 106 patients undergoing radiculography with a tangent-beam technique and Iopamidol, only 4 developed mild side effects, namely headache in three cases and headache with nausea in one. (Author)

  13. Amount of trace elements in marine cephalopods

    International Nuclear Information System (INIS)

    Ueda, Taiji; Nakahara, Motokazu; Ishii, Toshiaki; Suzuki, Yuzuru; Suzuki, Hamaji.

    1979-01-01

    For the estimation of internal radiation to human beings, the amounts of Mn, Fe, Cu, Zn, Co and Cs in 5 species of marine cephalopods were determined by atomic absorption spectrophotometry and neutron activation analysis, and then the concentration factors were calculated. The average amount and the concentration factor of the elements in the edible parts (mantle, arms and tentacles) of cephalopods are as follows: 0.14 mg, 2 x 10 2 for Mn, 1.8 mg, 2 x 10 2 for Fe, 2.0 mg, 7 x 10 2 for Cu, 12.2 mg, 1 x 10 3 for Zn, 5.3 μg, 6 x 10 1 for Co and 3.4 μg, 7 for Cs. The amounts of Fe, Co, Cu and Zn in the liver and the branchial heart were much higher than those in the edible parts, although those of Cs and Mn were almost the same. The Co content in the visceral organs of O. Vulgaris showed extremely high value, particularly in the branchial heart. (author)

  14. Comparing fixed-amount and progressive-amount DRO Schedules for tic suppression in youth with chronic tic disorders.

    Science.gov (United States)

    Capriotti, Matthew R; Turkel, Jennifer E; Johnson, Rachel A; Espil, Flint M; Woods, Douglas W

    2017-01-01

    Chronic tic disorders (CTDs) involve motor and/or vocal tics that often cause substantial distress and impairment. Differential reinforcement of other behavior (DRO) schedules of reinforcement produce robust, but incomplete, reductions in tic frequency in youth with CTDs; however, a more robust reduction may be needed to affect durable clinical change. Standard, fixed-amount DRO schedules have not commonly yielded such reductions, so we evaluated a novel, progressive-amount DRO schedule, based on its ability to facilitate sustained abstinence from functionally similar behaviors. Five youth with CTDs were exposed to periods of baseline, fixed-amount DRO (DRO-F), and progressive-amount DRO (DRO-P). Both DRO schedules produced decreases in tic rate and increases in intertic interval duration, but no systematic differences were seen between the two schedules on any dimension of tic occurrence. The DRO-F schedule was generally preferred to the DRO-P schedule. Possible procedural improvements and other future directions are discussed. © 2016 Society for the Experimental Analysis of Behavior.

  15. Forest amount affects soybean productivity in Brazilian agricultural frontier

    Science.gov (United States)

    Rattis, L.; Brando, P. M.; Marques, E. Q.; Queiroz, N.; Silverio, D. V.; Macedo, M.; Coe, M. T.

    2017-12-01

    Over the past three decades, large tracts of tropical forests have been converted to crop and pasturelands across southern Amazonia, largely to meet the increasing worldwide demand for protein. As the world's population continue to grow and consume more protein per capita, forest conversion to grow more crops could be a potential solution to meet such demand. However, widespread deforestation is expected to negatively affect crop productivity via multiple pathways (e.g., thermal regulation, rainfall, local moisture, pest control, among others). To quantify how deforestation affects crop productivity, we modeled the relationship between forest amount and enhanced vegetation index (EVI—a proxy for crop productivity) during the soybean planting season across southern Amazonia. Our hypothesis that forest amount causes increased crop productivity received strong support. We found that the maximum MODIS-based EVI in soybean fields increased as a function of forest amount across three spatial-scales, 0.5 km, 1 km, 2 km, 5 km, 10 km, 15 km and 20 km. However, the strength of this relationship varied across years and with precipitation, but only at the local scale (e.g., 500 meters and 1 km radius). Our results highlight the importance of considering forests to design sustainable landscapes.

  16. Involving women.

    Science.gov (United States)

    Agbo, J

    1994-01-01

    I am a primary health care (PHC) coordinator working with the May Day Rural project, a local NGO involved in integrated approaches and programs with rural communities in the Ga District of the Greater-Accra region in Ghana. When we talk about the community development approach we must first and foremost recognize that we are talking about women, because in the developing world frequent childbirths mean that her burden of mortality is higher than a man's; her workload is extremely heavy--whether in gardening, farming, other household duties, caring for the sick, or the rearing of children; she has a key role in PHC and community development, because men are always looking for greener pastures elsewhere, leaving the women behind. Women's concerns are critical in most health care projects and women and children are their main beneficiaries. Why not include women in the management team, project design, implementation and evaluation processes? That is what the May Day Rural project is practicing, encouraging women's participation and creating a relationship of trust. full text

  17. Polarographic determination of trace amounts of thorium

    Energy Technology Data Exchange (ETDEWEB)

    Zaofan Zhao; Xiaohua Cai; Peibiao Li; Handong Yang

    1986-07-01

    A sensitive linear-sweep polarographic method for the determination of thorium is described. It is based on the thorium complex with Xylidyl Blue I (XBI) in a medium containing ethylenediamine, 1, 10-phenanthroline, oxalic acid and ninhydrin, at pH 10.5-11.5. The complex has been proved to be Th(XBI)/sub 2/, with log ..beta..'=9.6. The method can be used to determine trace amounts of thorium over the range 3.5x10/sup -8/-3x10/sup -6/M. The detection limit is 1x10/sup -8/M. A solvent extraction procedure is necessary to eliminate interference from several cations. The method has been applied to determination of traces of thorium in minerals, with good results.

  18. Modeling and simulation of large HVDC systems

    Energy Technology Data Exchange (ETDEWEB)

    Jin, H.; Sood, V.K.

    1993-01-01

    This paper addresses the complexity and the amount of work in preparing simulation data and in implementing various converter control schemes and the excessive simulation time involved in modelling and simulation of large HVDC systems. The Power Electronic Circuit Analysis program (PECAN) is used to address these problems and a large HVDC system with two dc links is simulated using PECAN. A benchmark HVDC system is studied to compare the simulation results with those from other packages. The simulation time and results are provided in the paper.

  19. Infected Atopic Dermatitis Lesions Contain Pharmacologic Amounts of Lipoteichoic Acid

    Science.gov (United States)

    Travers, Jeffrey B.; Kozman, Amal; Mousdicas, Nico; Saha, Chandan; Landis, Megan; Al-Hassani, Mohammed; Yao, Weiguo; Yao, Yongxue; Hyatt, Ann-Marie; Sheehan, Michael P.; Haggstrom, Anita N.; Kaplan, Mark H.

    2009-01-01

    Background Bacterial infection with Staphylococcus aureus is a known trigger for worsening of atopic dermatitis (AD); the exact mechanisms by which bacterial infection worsens dermatitis are unknown. Objective We sought to characterize the amounts of the biologically active bacterial lipoprotein lipoteichoic acid (LTA) in infected AD lesions. Methods Eighty-nine children with clinically impetiginized lesions of AD were enrolled in this study. A lesion was graded clinically using the Eczema Area and Severity Index (EASI), and then wash fluid obtained from the lesion for quantitative bacterial culture, and measurement of LTA and cytokines. The staphylococcal isolate was tested for antibiotic susceptibilities. The patients were treated with a regimen that included topical corticosteroids and systemic antibiotics and the lesion was re-analyzed after two weeks. Results S. aureus was identified in 79 of 89 children enrolled in the study. The bacterial CFU correlated with the EASI lesional score (p = 0.04). LTA levels up to 9.8 μg/ml were measured in the wash fluid samples and the amounts correlated with the lesional EASI scores (p = 0.01) and S. aureus CFU (p < 0.001). Approximately 30% of clinically impetiginized AD lesions contained greater than 1 μg/ml LTA, amounts that exert effects on various cell types in vitro. Moreover, injection of skin tissue ex vivo with amounts of LTA found in AD lesions resulted in epidermal cytokine gene expression. Conclusions Pharmacologic levels of LTA are found in many infected atopic dermatitis lesions. Clinical Implications These findings suggest that staphylococcal LTA could be an important mediator of the increased skin inflammation associated with infected AD. Capsule Summary These studies demonstrate high levels of staphylococcal LTA are found on impetiginized AD lesions. Moreover, subjects harboring MRSA exhibited greater total body involvement of AD. PMID:19962742

  20. Laboratory for Large Data Research

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: The Laboratory for Large Data Research (LDR) addresses a critical need to rapidly prototype shared, unified access to large amounts of data across both the...

  1. The purchase decision process and involvement of the elderly regarding nonprescription products.

    Science.gov (United States)

    Reisenwitz, T H; Wimbish, G J

    1997-01-01

    The elderly or senior citizen is a large and growing market segment that purchases a disproportionate amount of health care products, particularly nonprescription products. This study attempts to examine the elderly's level of involvement (high versus low) and their purchase decision process regarding nonprescription or over-the-counter (OTC) products. Frequencies and percentages are calculated to indicate level of involvement as well as purchase decision behavior. Previous research is critiqued and managerial implications are discussed.

  2. 76 FR 59138 - Medicare Program; Medicare Appeals; Adjustment to the Amount in Controversy Threshold Amounts for...

    Science.gov (United States)

    2011-09-23

    ... Administrative Law Judge (ALJ) hearings and judicial review under the Medicare appeals process. The adjustment to the AIC threshold amounts will be effective for requests for ALJ hearings and judicial review filed on... $1,350 for judicial review. DATES: Effective Date: This notice is effective on January 1, 2012. FOR...

  3. 75 FR 58407 - Medicare Program; Medicare Appeals; Adjustment to the Amount in Controversy Threshold Amounts for...

    Science.gov (United States)

    2010-09-24

    ... Administrative Law Judge (ALJ) hearings and judicial review under the Medicare appeals process. The adjustment to the AIC threshold amounts will be effective for requests for ALJ hearings and judicial review filed on... judicial review. DATES: Effective Date: This notice is effective on January 1, 2011. FOR FURTHER...

  4. 78 FR 59702 - Medicare Program; Medicare Appeals: Adjustment to the Amount in Controversy Threshold Amounts for...

    Science.gov (United States)

    2013-09-27

    ... Administrative Law Judge (ALJ) hearings and judicial review under the Medicare appeals process. The adjustment to the AIC threshold amounts will be effective for requests for ALJ hearings and judicial review filed on... ALJ hearings and $1,430 for judicial review. DATES: This notice is effective on January 1, 2014. FOR...

  5. 77 FR 59618 - Medicare Program; Medicare Appeals; Adjustment to the Amount in Controversy Threshold Amounts for...

    Science.gov (United States)

    2012-09-28

    ... Administrative Law Judge (ALJ) hearings and judicial review under the Medicare appeals process. The adjustment to the AIC threshold amounts will be effective for requests for ALJ hearings and judicial review filed on... $1,400 for judicial review. Effective Date: This notice is effective on January 1, 2013. FOR FURTHER...

  6. Querying Large Biological Network Datasets

    Science.gov (United States)

    Gulsoy, Gunhan

    2013-01-01

    New experimental methods has resulted in increasing amount of genetic interaction data to be generated every day. Biological networks are used to store genetic interaction data gathered. Increasing amount of data available requires fast large scale analysis methods. Therefore, we address the problem of querying large biological network datasets.…

  7. Determination of micro amounts of praseodymium by analogue derivative spectrophotometry

    International Nuclear Information System (INIS)

    Ishii, Hajime; Satoh, Katsuhiko.

    1986-01-01

    Derivative spectrophotometry using the analogue differentiation circuit was applied to the determination of praseodymium at the ppm level. By the proposed method, in which the second or fourth derivative spectrum of the characteristic absorption band of praseodymium(III) at 444 nm is measured, as little as 3 ppm of praseodymium can be determined directly and easily even in the presence of large amounts of other rare earths without any prior separation. Interferences from neodymium, samarium, dysprosium, holmium and erbium ions which have characteristic absorption bands around 444 nm can easily be removed by utilizing the isosbestic point in the derivative spectra of praseodymium(III) and the interfering rare earth(III). (author)

  8. Does the amount of school choice matter for student engagement?

    Science.gov (United States)

    Vaughn, Michael G.; Witko, Christopher

    2013-01-01

    School choice may increase student engagement by enabling students to attend schools that more closely match their needs and preferences. But this effect on engagement may depend on the characteristics of the choices available. Therefore, we consider how the amount of educational choice of different types in a local educational marketplace affects student engagement using a large, national population of 8th grade students. We find that more choice of regular public schools in the elementary and middle school years is associated with a lower likelihood that students will be severely disengaged in eighth grade, and more choices of public schools of choice has a similar effect but only in urban areas. In contrast, more private sector choice does not have such a general beneficial effect. PMID:23682202

  9. 24 CFR 891.525 - Amount and terms of financing.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Amount and terms of financing. 891... Handicapped-Section 8 Assistance § 891.525 Amount and terms of financing. (a) The amount of financing approved... financing provided shall not exceed the lesser of: (1) The dollar amounts stated in paragraphs (b) through...

  10. 45 CFR 149.100 - Amount of reimbursement.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Amount of reimbursement. 149.100 Section 149.100... REQUIREMENTS FOR THE EARLY RETIREE REINSURANCE PROGRAM Reinsurance Amounts § 149.100 Amount of reimbursement... reimbursement in the amount of 80 percent of the costs for health benefits (net of negotiated price concessions...

  11. Boreal Forests Sequester Large Amounts of Mercury over Millennial Time Scales in the Absence of Wildfire.

    Science.gov (United States)

    Giesler, Reiner; Clemmensen, Karina E; Wardle, David A; Klaminder, Jonatan; Bindler, Richard

    2017-03-07

    Alterations in fire activity due to climate change and fire suppression may have profound effects on the balance between storage and release of carbon (C) and associated volatile elements. Stored soil mercury (Hg) is known to volatilize due to wildfires and this could substantially affect the land-air exchange of Hg; conversely the absence of fires and human disturbance may increase the time period over which Hg is sequestered. Here we show for a wildfire chronosequence spanning over more than 5000 years in boreal forest in northern Sweden that belowground inventories of total Hg are strongly related to soil humus C accumulation (R 2 = 0.94, p millennial time scales in the prolonged absence of fire.

  12. Non Relational Models for the Management of Large Amount of Astronomical Data

    Directory of Open Access Journals (Sweden)

    B. L. Martino

    2015-02-01

    Full Text Available The objective of this paper is the comparison between two different database typologies: the relational and the nonrelational architecture, in the context of the applications related to the use and distribution of astronomical data. The specific context is focused to problems quite different from those related to administrative and managerial environments within which were developed the leading technologies on which are based the modern systems of massive storage of data. The data provided by astronomical instrumentation are usually filtered out by the front-end system (trigger, anticoincidence, DSP etc., so they do not require special controls of congruence. Moreover, the related storage systems must be able to ensure an easy growth, minimizing human systemistic interventions and automating the related actions. The use of a non-relational architecture (NoSQL, offers great advantages during the insertion of informations within a data base, while the response speed of the queries is mainly tied to their type and complexity.

  13. The uniform design experimental research of a large amount of fly ash self-compaction concrete

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, M.; Ji, C.; Xiao, J. [Liaoning Technical University, Fuxin (China)

    2005-08-15

    The paper studied the effect of quantity of cementing material and fly ash, W/B (water-binder) ratio, admixture and sand percentage to the performance of super fly-ash self-compaction concrete. It also utilized the step-by-step regression analysis method in SPSS software to found regression equation, which uses the flow rate of concrete mixture and strength of concrete as objective function, and obtained the optimum mix proportion of super fly ash self-compaction by the optimization technology in the Matlab software.

  14. Study of steam condensation in SG tubes with large amount of nitrogen to be accumulated

    Energy Technology Data Exchange (ETDEWEB)

    Logvinov, S.A.; Sitnik, Y.K. [EDO Gidropress, Podolsk (Russian Federation)

    1997-12-31

    The effect of nitrogen during SG heat transfer under SBLOCA conditions have been studied. Depressurization of the primary side leads to release of nitrogen dissolved in the hydroaccumulator water. Nitrogen can accumulate in SGs and affect adversely heat transfer under reflux condenser conditions. The main objective of the study has been to show that nitrogen does not prevent heat transfer in SGs of the VVER-640 which is reactor plant of new generation. (orig.).

  15. Emphysematous gastritis secondary to ingestion of large amounts of Coca Cola.

    Science.gov (United States)

    Hadas-Halpren, I; Hiller, N; Guberman, D

    1993-01-01

    Acute emphysematous gastritis (AEG) is a life-threatening disease in which gas-forming bacteria invade the gastric wall and cause acute inflammation of it. The clinical presentation of the patient with AEG is stormy: severe sepsis which usually leads to an early death. Presented herein is a case of a 16-yr-old boy with AEG. There were no predisposing factors to the condition in this case. Gas invaded the stomach wall and portal venous system, as well as the duodenal wall, a finding that has not been reported previously. The clinical course was very severe but, in contrast to previously reported cases, recovery was very rapid and left no sequelae.

  16. New managing system of a large amount of images on Tore Supra

    International Nuclear Information System (INIS)

    Buravand, Y.; Ducobu, L.; Guilhem, D.; Roche, H.; Signoret, J.; Travere, J.M.; Utzel, N.

    2004-01-01

    After a major replacement of all internal components (terminated in 2002), Tore Supra has restarted operation with a new set of actively cooled components. The safety of these components relies on infrared (IR) thermography. Up to twelve IR cameras will be used to survey nearly all the high flux target zones which are essentially the 360 deg C toroidal pump limiter and the 5 power injection HF antennas. The high data rate produced by each camera ( ∼ 8 Mbytes/sec.) led us to implement a multi stages system: during experimentations, images are stored where they are acquired then, each night they are compressed using a lossy standard image compression algorithm (JPEG) and stored on a specialized IR data server. Between shots, acquisition systems act as servers and physicists can read data using a dedicated analysis software. For post-analysis purposes, all compressed images are read from the IR data server using the same analysis software or for in-depth analysis, physicists can use the Matlab interface we have developed. (authors)

  17. How and why does tomato accumulate a large amount of GABA in the fruit?

    OpenAIRE

    Takayama, Mariko; Ezura, Hiroshi

    2015-01-01

    γ-Aminobutyric acid (GABA) has received much attention as a health-promoting functional compound, and several GABA-enriched foods have been commercialized. In higher plants, GABA is primarily metabolized via a short pathway called the GABA shunt. The GABA shunt bypasses two steps (the oxidation of α-ketoglutarate to succinate) of the tricarboxylic acid (TCA) cycle via reactions catalysed by three enzymes: glutamate decarboxylase (GAD), GABA transaminase (GABA-T) and succinic semialdehyde dehy...

  18. How and why does tomato accumulate a large amount of GABA in the fruit?

    Directory of Open Access Journals (Sweden)

    Mariko eTakayama

    2015-08-01

    Full Text Available γ-Aminobutyric acid (GABA has received much attention as a health-promoting functional compound, and several GABA-enriched foods have been commercialized. In higher plants, GABA is primarily metabolized via a short pathway called the GABA shunt. The GABA shunt bypasses two steps (the oxidation of α-ketoglutarate to succinate of the tricarboxylic acid (TCA cycle via reactions catalysed by three enzymes: glutamate decarboxylase (GAD, GABA transaminase (GABA-T and succinic semialdehyde dehydrogenase (SSADH. The GABA shunt plays a major role in primary carbon and nitrogen metabolism and is an integral part of the TCA cycle under stress and non-stress conditions. Tomato is one of the major crops that accumulate a relatively high level of GABA in its fruits. The GABA levels in tomato fruits dramatically change during fruit development; the GABA levels increase from flowering to the mature green stage and then rapidly decrease during the ripening stage. Although GABA constitutes up to 50% of the free amino acids at the mature green stage, the molecular mechanism of GABA accumulation and the physiological function of GABA during tomato fruit development remain unclear. In this review, we summarize recent studies of GABA accumulation in tomato fruits and discuss the potential biological roles of GABA in tomato fruit development.

  19. Generation Expansion Planning with Large Amounts of Wind Power via Decision-Dependent Stochastic Programming

    DEFF Research Database (Denmark)

    Zhan, Yiduo; Zheng, Qipeng; Wang, Jianhui

    2016-01-01

    , the probability distribution function is determined by not only input parameters but also decision variables. To deal with the nonlinear constraints in our model, a quasi-exact solution approach is then introduced to reformulate the multistage stochastic investment model to a mixed-integer linear programming......Power generation expansion planning needs to deal with future uncertainties carefully, given that the invested generation assets will be in operation for a long time. Many stochastic programming models have been proposed to tackle this challenge. However, most previous works assume predetermined...

  20. Screening and characterization of Lactobacillus strains producing large amounts of exopolysaccharides

    NARCIS (Netherlands)

    Geel-Schutten, G.H. van; Flesch, F.; Brink, B. ten; Smith, M.R.; Dijkhuizen, L.

    1998-01-01

    A total of 182 Lactobacillus strains were screened for production of extracellular polysaccharides (EPS) by a new method: growth in liquid media with high sugar concentrations. Sixty EPS-positive strains were identified; 17 strains produced more than 100 mg/l soluble EPS. Sucrose was an excellent

  1. Simplified method for the determination of strontium-90 in large amounts of bone-ash

    International Nuclear Information System (INIS)

    Patti, F.; Jeanmaire, L.

    1966-06-01

    The principle of the determination is based on a 3-step process: 1) concentrating the strontium by attacking the ash with nitric acid; 2) elimination of residual phosphoric ions by a double precipitation of strontium oxalate; and 3) extraction of yttrium 90, counted in the oxalate form. The advantages of the method: -) using simple techniques it makes it possible to process 50 g of ash; -) the initial concentration of strontium considerably reduces the volume of the solutions as well as the size of precipitates handled. Fuming nitric acid is used in a specially designed burette. (authors) [fr

  2. Study of steam condensation in SG tubes with large amount of nitrogen to be accumulated

    Energy Technology Data Exchange (ETDEWEB)

    Logvinov, S A; Sitnik, Y K [EDO Gidropress, Podolsk (Russian Federation)

    1998-12-31

    The effect of nitrogen during SG heat transfer under SBLOCA conditions have been studied. Depressurization of the primary side leads to release of nitrogen dissolved in the hydroaccumulator water. Nitrogen can accumulate in SGs and affect adversely heat transfer under reflux condenser conditions. The main objective of the study has been to show that nitrogen does not prevent heat transfer in SGs of the VVER-640 which is reactor plant of new generation. (orig.).

  3. Empirical relationships between tree fall and landscape-level amounts of logging and fire.

    Science.gov (United States)

    Lindenmayer, David B; Blanchard, Wade; Blair, David; McBurney, Lachlan; Stein, John; Banks, Sam C

    2018-01-01

    Large old trees are critically important keystone structures in forest ecosystems globally. Populations of these trees are also in rapid decline in many forest ecosystems, making it important to quantify the factors that influence their dynamics at different spatial scales. Large old trees often occur in forest landscapes also subject to fire and logging. However, the effects on the risk of collapse of large old trees of the amount of logging and fire in the surrounding landscape are not well understood. Using an 18-year study in the Mountain Ash (Eucalyptus regnans) forests of the Central Highlands of Victoria, we quantify relationships between the probability of collapse of large old hollow-bearing trees at a site and the amount of logging and the amount of fire in the surrounding landscape. We found the probability of collapse increased with an increasing amount of logged forest in the surrounding landscape. It also increased with a greater amount of burned area in the surrounding landscape, particularly for trees in highly advanced stages of decay. The most likely explanation for elevated tree fall with an increasing amount of logged or burned areas in the surrounding landscape is change in wind movement patterns associated with cutblocks or burned areas. Previous studies show that large old hollow-bearing trees are already at high risk of collapse in our study area. New analyses presented here indicate that additional logging operations in the surrounding landscape will further elevate that risk. Current logging prescriptions require the protection of large old hollow-bearing trees on cutblocks. We suggest that efforts to reduce the probability of collapse of large old hollow-bearing trees on unlogged sites will demand careful landscape planning to limit the amount of timber harvesting in the surrounding landscape.

  4. 21 CFR 101.12 - Reference amounts customarily consumed per eating occasion.

    Science.gov (United States)

    2010-04-01

    ...,3,4 Product category Reference amount Label statement 5 Cereals, dry instant 15 g _ cup (_ g...) (_ g); _ piece(s) (_ g) for large pieces (e.g., large shells or lasagna noodles) or 2 oz (56 g/visual... chow mein noodles 25 g _ cup(s) (_ g) Starches, e.g., cornstarch, potato starch, tapioca, etc. 10 g...

  5. Using GRACE to constrain precipitation amount over cold mountainous basins

    Science.gov (United States)

    Behrangi, Ali; Gardner, Alex S.; Reager, John T.; Fisher, Joshua B.

    2017-01-01

    Despite the importance for hydrology and climate-change studies, current quantitative knowledge on the amount and distribution of precipitation in mountainous and high-elevation regions is limited due to instrumental and retrieval shortcomings. Here by focusing on two large endorheic basins in High Mountain Asia, we show that satellite gravimetry (Gravity Recovery and Climate Experiment (GRACE)) can be used to provide an independent estimate of monthly accumulated precipitation using mass balance equation. Results showed that the GRACE-based precipitation estimate has the highest agreement with most of the commonly used precipitation products in summer, but it deviates from them in cold months, when the other products are expected to have larger errors. It was found that most of the products capture about or less than 50% of the total precipitation estimated using GRACE in winter. Overall, Global Precipitation Climatology Project (GPCP) showed better agreement with GRACE estimate than other products. Yet on average GRACE showed 30% more annual precipitation than GPCP in the study basins. In basins of appropriate size with an absence of dense ground measurements, as is a typical case in cold mountainous regions, we find GRACE can be a viable alternative to constrain monthly and seasonal precipitation estimates from other remotely sensed precipitation products that show large bias.

  6. 12 CFR 347.120 - Computation of investment amounts.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Computation of investment amounts. 347.120... GENERAL POLICY INTERNATIONAL BANKING § 347.120 Computation of investment amounts. In computing the amount that may be invested in any foreign organization under §§ 347.117 through 347.119, any investments held...

  7. 29 CFR 4.142 - Contracts in an indefinite amount.

    Science.gov (United States)

    2010-07-01

    ... McNamara-O'Hara Service Contract Act Determining Amount of Contract § 4.142 Contracts in an indefinite amount. (a) Every contract subject to this Act which is indefinite in amount is required to contain the....), a case arising under the Walsh-Healey Public Contracts Act. Such a contract, which may be in the...

  8. 46 CFR 308.303 - Amounts insured under interim binder.

    Science.gov (United States)

    2010-10-01

    ... 308.303 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE Second Seamen's War Risk Insurance § 308.303 Amounts insured under interim binder. The amounts insured are the amounts specified in the Second Seamen's War Risk Policy (1955) or as modified by shipping...

  9. Modeling metabolic response to changes of enzyme amount in ...

    African Journals Online (AJOL)

    Based on the work of Hynne et al. (2001), in an in silico model of glycolysis, Saccharomyces cerevisiae is established by introducing an enzyme amount multiple factor (.) into the kinetic equations. The model is aimed to predict the metabolic response to the change of enzyme amount. With the help of .α, the amounts of ...

  10. 7 CFR 1710.107 - Amount lent for acquisitions.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Amount lent for acquisitions. 1710.107 Section 1710... GUARANTEES Loan Purposes and Basic Policies § 1710.107 Amount lent for acquisitions. The maximum amount that will be lent for an acquisition is limited to the value of the property, as determined by RUS. If the...

  11. DHA involvement in neurotransmission process

    OpenAIRE

    Vancassel Sylvie; Aïd Sabah; Denis Isabelle; Guesnet Philippe; Lavialle Monique

    2007-01-01

    The very high enrichment of the nervous system in the polyunsaturated fatty acids, arachidonic (AA, 20: 4n-6) and docosahexaenoic acids (DHA, 22: 6n-3), is dependant of the dietary availability of their respective precursors, linoleic (18: 2n-6) and_-linolenic acids (18: 3n-3). Inadequate amounts of DHA in brain membranes have been linked to a wide variety of abnormalities ranging from visual acuity and learning irregularities, to psychopathologies. However, the molecular mechanisms involved ...

  12. Obtaining accurate amounts of mercury from mercury compounds via electrolytic methods

    Science.gov (United States)

    Grossman, M.W.; George, W.A.

    1987-07-07

    A process is described for obtaining pre-determined, accurate rate amounts of mercury. In one embodiment, predetermined, precise amounts of Hg are separated from HgO and plated onto a cathode wire. The method for doing this involves dissolving a precise amount of HgO which corresponds to a pre-determined amount of Hg desired in an electrolyte solution comprised of glacial acetic acid and H[sub 2]O. The mercuric ions are then electrolytically reduced and plated onto a cathode producing the required pre-determined quantity of Hg. In another embodiment, pre-determined, precise amounts of Hg are obtained from Hg[sub 2]Cl[sub 2]. The method for doing this involves dissolving a precise amount of Hg[sub 2]Cl[sub 2] in an electrolyte solution comprised of concentrated HCl and H[sub 2]O. The mercurous ions in solution are then electrolytically reduced and plated onto a cathode wire producing the required, pre-determined quantity of Hg. 1 fig.

  13. Constraining precipitation amount and distribution over cold regions using GRACE

    Science.gov (United States)

    Behrangi, A.; Reager, J. T., II; Gardner, A. S.; Fisher, J.

    2017-12-01

    Current quantitative knowledge on the amount and distribution of precipitation in high-elevation and high latitude regions is limited due to instrumental and retrieval shortcomings. Here we demonstrate how that satellite gravimetry (Gravity Recovery and Climate Experiment, GRACE) can be used to provide an independent estimate of monthly accumulated precipitation using mass balance. Results showed that the GRACE-based precipitation estimate has the highest agreement with most of the commonly used precipitation products in summer, but it deviates from them in cold months, when the other products are expected to have larger error. We also observed that as near surface temperature decreases products tend to underestimate accumulated precipitation retrieved from GRACE. The analysis performed using various products such as GPCP, GPCC, TRMM, and gridded station data over vast regions in high latitudes and two large endorheic basins in High Mountain Asia. Based on the analysis over High Mountain Asia it was found that most of the products capture about or less than 50% of the total precipitation estimated using GRACE in winter. Overall, GPCP showed better agreement with GRACE estimate than other products. Yet on average GRACE showed 30% more annual precipitation than GPCP in the study basin.

  14. Ion transporters involved in acidification of the resorption lacuna in osteoclasts

    DEFF Research Database (Denmark)

    Henriksen, K.; Sorensen, M.G.; Jensen, V.K.

    2008-01-01

    Osteoclasts possess a large amount of ion transporters, which participate in bone resorption; of these, the vacuolar-adenosine trisphosphatase (V-ATPase) and the chloride-proton antiporter ClC-7 acidify the resorption lacuna. However, whether other ion transporters participate in this process is ......, including carbonic anhydrase II, the NHEs, and potassium-chloride cotransporters, are all involved in resorption but do not seem to directly be involved in acidification of the lysosomes Udgivelsesdato: 2008/9......Osteoclasts possess a large amount of ion transporters, which participate in bone resorption; of these, the vacuolar-adenosine trisphosphatase (V-ATPase) and the chloride-proton antiporter ClC-7 acidify the resorption lacuna. However, whether other ion transporters participate in this process...

  15. Corrosion of Pipeline and Wellbore Steel by Liquid CO2 Containing Trace Amounts of Water and SO2

    Science.gov (United States)

    McGrail, P.; Schaef, H. T.; Owen, A. T.

    2009-12-01

    Carbon dioxide capture and storage in deep saline formations is currently considered the most attractive option to reduce greenhouse gas emissions with continued use of fossil fuels for energy production. Transporting captured CO2 and injection into suitable formations for storage will necessarily involve pipeline systems and wellbores constructed of carbon steels. Industry standards currently require nearly complete dehydration of liquid CO2 to reduce corrosion in the pipeline transport system. However, it may be possible to establish a corrosion threshold based on H2O content in the CO2 that could allow for minor amounts of H2O to remain in the liquid CO2 and thereby eliminate a costly dehydration step. Similarly, trace amounts of sulfur and nitrogen compounds common in flue gas streams are currently removed through expensive desulfurization and catalytic reduction processes. Provided these contaminants could be safely and permanently transported and stored in the geologic reservoir, retrofits of existing fossil-fuel plants could address comprehensive emissions reductions, including CO2 at perhaps nearly the same capital and operating cost. Because CO2-SO2 mixtures have never been commercially transported or injected, both experimental and theoretical work is needed to understand corrosion mechanisms of various steels in these gas mixtures containing varying amounts of water. Experiments were conducted with common tool steel (AISI-01) and pipeline steel (X65) immersed in liquid CO2 at room temperature containing ~1% SO2 and varying amounts of H2O (0 to 2500 ppmw). A threshold concentration of H2O in the liquid CO2-SO2 mixture was established based on the absence of visible surface corrosion. For example, experiments exposing steel to liquid CO2-SO2 containing ~300 ppmw H2O showed a delay in onset of visible corrosion products and minimal surface corrosion was visible after five days of testing. However increasing the water content to 760 ppmw produced extensive

  16. Disentangling the Effects of Precipitation Amount and Frequency on the Performance of 14 Grassland Species

    Science.gov (United States)

    Didiano, Teresa J.; Johnson, Marc T. J.; Duval, Tim P.

    2016-01-01

    Climate change is causing shifts in the amount and frequency of precipitation in many regions, which is expected to have implications for plant performance. Most research has examined the impacts of the amount of precipitation on plants rather than the effects of both the amount and frequency of precipitation. To understand how climate-driven changes in precipitation can affect grassland plants, we asked: (i) How does the amount and frequency of precipitation affect plant performance? (ii) Do plant functional groups vary in their response to variable precipitation? To answer these questions we grew 14 monocot and eudicot grassland species and conducted a factorial manipulation of the amount (70 vs 90mm/month) and frequency (every 3, 15, or 30 days) of precipitation under rainout shelters. Our results show that both the amount and frequency of precipitation impact plant performance, with larger effects on eudicots than monocots. Above- and below-ground biomass were affected by the amount of precipitation and/or the interaction between the amount and frequency of precipitation. Above-ground biomass increased by 21–30% when the amount of precipitation was increased. When event frequency was decreased from 3 to 15 or 30 days, below-ground biomass generally decreased by 18–34% in the 70 mm treatment, but increased by 33–40% in the 90 mm treatment. Changes in stomatal conductance were largely driven by changes in event frequency. Our results show that it is important to consider changes in both the amount and frequency of precipitation when predicting how plant communities will respond to variable precipitation. PMID:27622497

  17. Large window median filtering on Clip7

    Energy Technology Data Exchange (ETDEWEB)

    Mathews, K N

    1983-07-01

    Median filtering has been found to be a useful operation to perform on images in order to reduce random noise while preserving edges of objects. However, in some cases, as the resolution of the image increases, so too does the required window size of the filter. For parallel array processors, this leads to problems when dealing with the large amount of data involved. That is to say that there tend to be problems over slow access of data from pixels over a large neighbourhood, lack of available storage of this data during the operation and long computational times for finding the median. An algorithm for finding the median, designed for use on byte wide architecture parallel array processors is presented together with its implementation on Clip7, a scanning array of such processors. 6 references.

  18. An Estimation of Construction and Demolition Debris in Seoul, Korea: Waste Amount, Type, and Estimating Model.

    Science.gov (United States)

    Seo, Seongwon; Hwang, Yongwoo

    1999-08-01

    Construction and demolition (C&D) debris is generated at the site of various construction activities. However, the amount of the debris is usually so large that it is necessary to estimate the amount of C&D debris as accurately as possible for effective waste management and control in urban areas. In this paper, an effective estimation method using a statistical model was proposed. The estimation process was composed of five steps: estimation of the life span of buildings; estimation of the floor area of buildings to be constructed and demolished; calculation of individual intensity units of C&D debris; and estimation of the future C&D debris production. This method was also applied in the city of Seoul as an actual case, and the estimated amount of C&D debris in Seoul in 2021 was approximately 24 million tons. Of this total amount, 98% was generated by demolition, and the main components of debris were concrete and brick.

  19. Carbon-Nitrogen Relationships during the Humification of Cellulose in Soils Containing Different Amounts of Clay

    DEFF Research Database (Denmark)

    Sørensen, Lasse Holst

    1981-01-01

    the 2 soils with the high content of clay had a relatively high content of available unlabeled soil-N which was used for synthesis of metabolic material. The proportionate retention of labeled C for a given soil was largely independent of the size of the amendments, whereas the proportionate amount....... Some of the labeled organic N when mineralized was re-incorporated into organic compounds containing increasing proportions of native soil-C, whereas labeled C when mineralized as CO2 disappeared from the soils. The amount of labeled amino acid-C, formed during decomposition of the labeled cellulose...... was most intense, and it held throughout the 4 yr of the incubation; proportionally it was independent of the amount of cellulose added and the temperature. The labeled amino acid-N content was not directly related to the amount of clay in the soil, presumably because more unlabeled soil-N was available...

  20. Estimation of erosion amount by geochemical characteristic in the Horonobe area, northern Hokkaido

    International Nuclear Information System (INIS)

    Takahashi, Kazuharu; Niizato, Tadafumi; Yasue, Ken-ichi; Ishii, Eiichi

    2005-08-01

    This article presents the results of the estimated amount of erosion and uplifting based on mineralogy and organic geochemical characters of the Neogene siliceous rock (Wakkanai and Koetoi Formations) in Horonobe. As a result of the transformational change of silica minerals, it was clarified that the erosion amount was about 0.66 [m ky -1 ] or more at the large uplift site, and about 0.21 [m ky -1 ] or more at the small uplift site at Hokushin region, Horonobe area. In this case of the correlation with the palaeo-geothermal temperature and the sterane/sterene ratio, the ratio is effective measure to estimate the burial depth and erosion amount. We think that the estimation of the amount of erosion and uplifting became possible in high resolution by the organic geochemical character. (author)

  1. 5 CFR 870.704 - Amount of Option A.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Amount of Option A. 870.704 Section 870... of Option A. (a) The amount of Option A coverage an annuitant or compensationer can continue is $10,000. (b) An annuitant's or compensationer's Option A coverage reduces by 2 percent of the original...

  2. 24 CFR 232.565 - Maximum loan amount.

    Science.gov (United States)

    2010-04-01

    ... URBAN DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES MORTGAGE INSURANCE FOR NURSING HOMES, INTERMEDIATE CARE FACILITIES, BOARD AND CARE HOMES, AND ASSISTED... Fire Safety Equipment Eligible Security Instruments § 232.565 Maximum loan amount. The principal amount...

  3. 39 CFR 601.111 - Interest on claim amounts.

    Science.gov (United States)

    2010-07-01

    ... that date is later, until the date of payment. Simple interest will be paid at the rate established by... 39 Postal Service 1 2010-07-01 2010-07-01 false Interest on claim amounts. 601.111 Section 601.111... PROPERTY RIGHTS OTHER THAN PATENTS PURCHASING OF PROPERTY AND SERVICES § 601.111 Interest on claim amounts...

  4. 22 CFR 226.73 - Collection of amounts due.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Collection of amounts due. 226.73 Section 226.73 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS After-the-Award Requirements § 226.73 Collection of amounts due. (a...

  5. Potentiometric determination of milligram amounts of uranium by semiautomatic titrator

    International Nuclear Information System (INIS)

    Ryzhinskij, M.V.; Stepanov, A.V.; Preobrazhenskaya, L.D.; Solntseva, L.F.; Gromova, E.A.

    1978-01-01

    A semiautomatic titrator is described which allows gravimetriotentiometricc-p titrat mg amounts of substances. Milligram amounts of uranium (absolute contents and oxygen/uranium ratio) in U 3 O 8 were determined as an example of the titrator action. The relative standard deviation was less than 0.001

  6. 12 CFR 209.4 - Amounts and payments.

    Science.gov (United States)

    2010-01-01

    ... CANCELLATION OF FEDERAL RESERVE BANK CAPITAL STOCK (REGULATION I) § 209.4 Amounts and payments. (a) Amount of... lesser of 15 percent or 100 shares of its Reserve Bank capital stock, it shall file with the appropriate Reserve Bank an application for issue or cancellation of Reserve Bank capital stock in order to adjust its...

  7. 45 CFR 1225.11 - Amount of attorney fees.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Amount of attorney fees. 1225.11 Section 1225.11... § 1225.11 Amount of attorney fees. (a) When a decision of the agency provides for an award of attorney's fees or costs, the complainant's attorney shall submit a verified statement of costs and attorney's...

  8. 46 CFR 282.20 - Amount of subsidy payable.

    Science.gov (United States)

    2010-10-01

    ... Rates. Daily ODS rates shall be used to quantify the amount of ODS payable. The daily ODS rate... items is the daily amount of ODS payable for approved vessel operating days, excluding reduced crew... the daily wage ODS rate to conform to the complement remaining on the vessel. The man-day reduction...

  9. 29 CFR 530.302 - Amounts of civil money penalties.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Amounts of civil money penalties. 530.302 Section 530.302... EMPLOYMENT OF HOMEWORKERS IN CERTAIN INDUSTRIES Civil Money Penalties § 530.302 Amounts of civil money penalties. (a) A civil money penalty, not to exceed $500 per affected homeworker for any one violation, may...

  10. 42 CFR 438.704 - Amounts of civil money penalties.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Amounts of civil money penalties. 438.704 Section... SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS MANAGED CARE Sanctions § 438.704 Amounts of civil money penalties. (a) General rule. The limit on, or the maximum civil money penalty the State may impose varies...

  11. 20 CFR 362.12 - Computation of amount of reimbursement.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Computation of amount of reimbursement. 362.12 Section 362.12 Employees' Benefits RAILROAD RETIREMENT BOARD INTERNAL ADMINISTRATION, POLICY AND... the cost of repair is the amount payable. (b) Depreciation in value of an item of personal property is...

  12. 28 CFR 70.73 - Collection of amounts due.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Collection of amounts due. 70.73 Section 70.73 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) UNIFORM ADMINISTRATIVE REQUIREMENTS... OTHER NON-PROFIT ORGANIZATIONS After-the-Award Requirements § 70.73 Collection of amounts due. (a) Any...

  13. Amounts of NPK removed from soil in harvested coffee berries as ...

    African Journals Online (AJOL)

    Monthly samples of ripened improved robusta coffee berries from compact and large growth forms from three locations, which are representative of the main ecological zones where coffee is grown in Ghana, were taken for 3 years. The pulp and parchment and beans were analysed for N, P and K contents. The amounts of ...

  14. Act of 25 February 1976 amending amounts and limits of the Civil Law

    International Nuclear Information System (INIS)

    1976-01-01

    The Federal Act of 29 April 1964 on nuclear third party liability was modified by Section XXXIII of the Federal Act of 25 February 1976 amending amounts and limits fixed by the Civil Law. This modification came into force on 1 April 1976. For operators of nuclear installations and carriers the ceiling is now 500 million Austrian schillings. For radioisotope holders, the maximum amount depends on the radioactivity and the radiotoxicity of the isotope involved. The present ceiling ranges from 1.2 to 18 million schillings. (NEA) [fr

  15. Patient involvement in hospital architecture

    DEFF Research Database (Denmark)

    Herriott, Richard

    2017-01-01

    the structure of the design process, identification and ranking of stakeholders, the methods of user-involvement and approaches to accessibility. The paper makes recommendations for a change of approach to user-participation in large-scale, long-duration projects. The paper adds new insight on an under...

  16. Parental Involvement in Norwegian Schools

    Science.gov (United States)

    Paulsen, Jan Merok

    2012-01-01

    This article examines findings on key challenges of school-parent relations in Norway. The review is based on recent large-scale studies on several issues, including formalized school-parent cooperation, parental involvement in the pedagogical discourse, and teacher perspectives on the parents' role in the school community. Findings suggest a…

  17. Large deviations

    CERN Document Server

    Varadhan, S R S

    2016-01-01

    The theory of large deviations deals with rates at which probabilities of certain events decay as a natural parameter in the problem varies. This book, which is based on a graduate course on large deviations at the Courant Institute, focuses on three concrete sets of examples: (i) diffusions with small noise and the exit problem, (ii) large time behavior of Markov processes and their connection to the Feynman-Kac formula and the related large deviation behavior of the number of distinct sites visited by a random walk, and (iii) interacting particle systems, their scaling limits, and large deviations from their expected limits. For the most part the examples are worked out in detail, and in the process the subject of large deviations is developed. The book will give the reader a flavor of how large deviation theory can help in problems that are not posed directly in terms of large deviations. The reader is assumed to have some familiarity with probability, Markov processes, and interacting particle systems.

  18. 26 CFR 1.465-20 - Treatment of amounts borrowed from certain persons and amounts protected against loss.

    Science.gov (United States)

    2010-04-01

    ... not increase the taxpayer's amount at risk because they are borrowed from a person who has an interest in the activity other than that of a creditor or from a person who is related to a person (other than the taxpayer) who has an interest in the activity other than that of a creditor; and (2) Amounts...

  19. Consumers' reaction towards involvement of large retailers in selling ...

    African Journals Online (AJOL)

    ... as to understand factors influencing purchase decision and, (2) Cluster analysis ... 'fair deal', 'fair trade promotion', 'social responsibility' and 'against own label' ... major factors that influence consumers' intention to purchase fair trade coffee ...

  20. Collisions involving energy transfer between atoms with large angular moments

    International Nuclear Information System (INIS)

    Vdovin, Yu.A.; Galitskij, V.M.

    1975-01-01

    Study is made of the collisions of excited and nonexcited atoms with a small resonance defect, assuming that the excited and ground states of each atom are bound via an allowed dipole transition and that intrinsic moments of states are great. In such an approximation the atomic interaction is defined by a dipole-dipole interaction operator. Equations for amplitudes are derived for two cases: (1) the first atom is in an excited state while the second is in the ground state and (2) the first atom is in the ground state while the second is in an excited state. The problem is solved in the approximation that the moments of the excited and ground states of each atom are equal. An expression for the excitation transfer cross section is written down. Analysis of this expression shows that the excitation transfer cross section at first increases with removal from the exact resonance and reaches resonance at lambda approximately 0.1 (lambda is a dimensionless parameter which is equal to the ratio of the resonance defect Δ to the interaction at spacings of the order of the Weisskopf radius). Only at lambda >0.16 does the cross section become smaller than the resonance one. This effect is due to the interaction Hamiltonian approximation adopted in the present study

  1. Who and What Does Involvement Involve?

    DEFF Research Database (Denmark)

    Hansen, Jeppe Oute; Petersen, Anders; Huniche, Lotte

    2015-01-01

    This article gives an account of aspects of a multi-sited field study of involvement of relatives in Danish psychiatry. By following metaphors of involvement across three sites of the psychiatric systema family site, a clinical site and a policy sitethe first author (J.O.) investigated how...... theoretical perspective laid out by Ernesto Laclau and Chantal Mouffe, the aim of this study is to show how the dominant discourse about involvement at the political and clinical sites is constituted by understandings of mentally ill individuals and by political objectives of involvement. The analysis...... the responsibility toward the mental health of the ill individual as well as toward the psychological milieu of the family....

  2. USING OF THE COVER AMOUNTS METHOD FOR OPTIMIZATION OF INCOME

    Directory of Open Access Journals (Sweden)

    A. V. Volkov

    2007-01-01

    Full Text Available The method of cover amounts (marginal income gives possibility to determine profitableness of each kind of the production and their real contribution into the result of work of enterprise.

  3. Nuclear liability amounts on the rise for nuclear installations

    International Nuclear Information System (INIS)

    Vasquez-Maignan, Ximena; Schwartz, Julia; Kuzeyli, Kaan

    2015-01-01

    The NEA Table on Nuclear Operator Liability Amounts and Financial Security Limits (NEA 'Liability Table'), which covers 71 countries, aims to provide one of the most comprehensive listings of nuclear liability amounts and financial security limits. The current and revised Paris and Brussels Supplementary Conventions ('Paris-Brussels regime'), the original and revised Vienna Conventions ('Vienna regime') and the Convention on Supplementary Compensation for Nuclear Damage, newly entered into force in April 2015, provide for the minimum amounts to be transposed in the national legislation of states parties to the conventions, and have served as guidelines for non-convention states. This article examine in more detail increases in the liability amounts provided for under these conventions, as well as examples of non-convention states (China, India and Korea)

  4. Amount of Future Forest Edge at a 2 Hectare Scale

    Data.gov (United States)

    U.S. Environmental Protection Agency — Forests provide economic and ecological value. High amounts of forest edge indicates a highly fragmented forest, which generally diminishes those economic and...

  5. 41 CFR 105-56.019 - Offset amount.

    Science.gov (United States)

    2010-07-01

    ... Administration 56-SALARY OFFSET FOR INDEBTEDNESS OF FEDERAL EMPLOYEES TO THE UNITED STATES Centralized Salary... referred for offset under this subpart is $100. (b) The amount offset from a salary payment under this... resolved to the satisfaction of GSA. ...

  6. Amount of Forest Edge at a 65 Hectare Scale

    Data.gov (United States)

    U.S. Environmental Protection Agency — Forests provide economic and ecological value. High amounts of forest edge indicates a highly fragmented forest, which generally diminishes those economic and...

  7. Amount of Future Forest Edge at a 65 Hectare scale

    Data.gov (United States)

    U.S. Environmental Protection Agency — Forests provide economic and ecological value. High amounts of forest edge indicates a highly fragmented forest, which generally diminishes those economic and...

  8. Amount of Forest Edge at a 2 Hectare Scale

    Data.gov (United States)

    U.S. Environmental Protection Agency — Forests provide economic and ecological value. High amounts of forest edge indicates a highly fragmented forest, which generally diminishes those economic and...

  9. 24 CFR 17.48 - Computation of amount of award.

    Science.gov (United States)

    2010-04-01

    ... be no allowance for replacement cost or for appreciation in the value of the property. Subject to... repairs does not exceed the amount allowable under paragraph (a)(1) of this section. (b) Depreciation in...

  10. Evaluation of the amount of apically extruded debris during ...

    African Journals Online (AJOL)

    2015-04-06

    Apr 6, 2015 ... Objective: To evaluate the amount of apically extruded debris during retreatment (with or without solvent) of root canals filled by two ... These filling materials can be used with several obturation .... The tip of the master cone.

  11. 24 CFR 206.105 - Amount of MIP.

    Science.gov (United States)

    2010-04-01

    ... DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES HOME EQUITY CONVERSION MORTGAGE INSURANCE Contract Rights and Obligations Mortgage Insurance Premiums § 206.105 Amount of...

  12. Sugar amount analysis in food from Lithuanian food market

    OpenAIRE

    Gudauskaitė, Milda

    2015-01-01

    When taking too much simple sugar, especially sucrose, harmful health effects occur: more tooth decay occurs, the excess sugar coverts into fat, digestive system gets irritated, increase of weight, possibility in increasing of developing cancer cells, pancreatic and other misbalances in the endocrine organs. Thesis goal: to perform sugar amount analysis in Lithuanian food market Analysis methodology. Assessing the amount of sugar (g/100g) there was analyzed 147 major food la...

  13. Plasmonic Titania Photo catalysts Active under UV and Visible-Light Irradiation: Influence of Gold Amount, Size, and Shape

    International Nuclear Information System (INIS)

    Kowalska, E.; Rau, S.; Kowalska, E.; Kowalska, E.; Ohtani, B.

    2012-01-01

    Plasmonic titania photo catalysts were prepared by titania modification with gold by photo deposition. It was found that for smaller amount of deposited gold (≤ 0.1 wt%), anatase presence and large surface area were beneficial for efficient hydrogen evolution during methanol dehydrogenation. After testing twelve amounts of deposited gold on large rutile titania, the existence of three optima for 0.5, 2 and >6 wt% of gold was found during acetic acid degradation. Under visible light irradiation, in the case of small gold NPs deposited on fine anatase titania, the dependence of photo activity on gold amount was parabolic, and large gold amount (2 wt%), observable as an intensively coloured powder, caused photo activity decrease. While for large gold NPs deposited on large rutile titania, the dependence represented cascade increase, due to change of size and shape of deposited gold with its amount increase. It has been thought that spherical/hemispherical shape of gold NPs, in comparison with rod-like ones, is beneficial for higher level of photo activity under visible light irradiation. For all tested systems and regardless of deposited amount of gold, each rutile Au/TiO 2 photo catalyst of large gold and titania NPs exhibited much higher photo activity than anatase Au/TiO 2 of small gold and titania NPs

  14. Scientists Involved in K-12 Education

    Science.gov (United States)

    Robigou, V.

    2004-12-01

    The publication of countless reports documenting the dismal state of science education in the 1980s, and the Third International Mathematics and Science Study (TIMMS) report (1996) called for a wider involvement of the scientific community in K-12 education and outreach. Improving science education will not happen without the collaboration of educators and scientists working in a coordinated manner and it requires a long-term, continuous effort. To contribute effectively to K-12 education all scientists should refer to the National Science Education Standards, a set of policies that guide the development of curriculum and assessment. Ocean scientists can also specifically refer to the COSEE recommendations (www.cosee.org) that led to the creation of seven regional Centers for Ocean Sciences Education Excellence. Scientists can get involved in K-12 education in a multitude of ways. They should select projects that will accommodate time away from their research and teaching obligations, their talent, and their interest but also contribute to the education reform. A few examples of effective involvement are: 1) collaborating with colleagues in a school of education that can lead to better education of all students and future teachers, 2) acting as a resource for a national program or a local science fair, 3) serving on the advisory board of a program that develops educational material, 4) speaking out at professional meetings about the value of scientists' involvement in education, 5) speaking enthusiastically about the teaching profession. Improving science education in addition to research can seem a large, overwhelming task for scientists. As a result, focusing on projects that will fit the scientist's needs as well as benefit the science reform is of prime importance. It takes an enormous amount of work and financial and personnel resources to start a new program with measurable impact on students. So, finding the right opportunity is a priority, and stepping

  15. Fostering employee involvement.

    Science.gov (United States)

    Beecher, G P

    1997-11-01

    Every year, the ODA's Economics of Practice Committee, with the help of an independent consulting firm, carries out the Cost of Practice Monitor which tracks the various costs of running a dental practice in Ontario. This article is the result of a joint ODA-Arthur Andersen initiative to provide members with detailed information from the Monitor. Over the next year, there will be a series of articles published under the heading "Best practises for Ontario's Dental Practices." The article featured in this issue focuses on wage expenses in dental practices and how to foster employee involvement as a means of addressing cost-productivity issues. Furthermore, information relating to wage expenses may be used by practitioners to benchmark their practice against the average Ontario dental practice. Appendix C was developed for this purpose. Through benchmarking, the practitioner may gain insight into ways of evaluating their practice and in addressing issues that could improve the management of the practice. For a long time, concepts of best business practises were applied only to manufacturing organizations or large multi-national corporations but experience has demonstrated that these activities are universal to all organizations, including service companies, schools, government and not-for-profit organizations.

  16. CT and angiographic analysis of posterior communicating artery aneurysms: What factors influence the amount of subarachnoid blood?

    International Nuclear Information System (INIS)

    Kim, Young Min; Jung, Kun Sik; Rho, Myung Ho; Choi, Pil Youb; Sung, Young Soon; Kwon, Jae Soo; Lee, Sang Wook

    1998-01-01

    To determine how clinical and angiographic factors relate to the amount of subarachnoid blood detected by computerized tomography in patients with a ruptured aneurysm. Between January 1996 and December 1997, 22 patients with a posterior communicating artery aneurysm were retrospectively evaluated. Oval(three of four cases), funnel(both cases), and daughter-sac (four of five cases) types of aneurysmal sac were found among the 13 patients with a large amount of subarachnoid blood;eight of these had a past history of hyertension or diabetes. Seven of eleven cases of cylindricaltype aneurysmal sac were found among the 9 patients with a small amount of sularachnoid blood;eight of these had no past history of hypertension or diabetes. The average S/N ratio (ratio of maximum sac length to neck diameter) of patients with a small amount of blood was higher than that of patients with a large amount of blood(2.72 vs 2.07). Although many factors influence the amount of subarachnoid blood in an aneurysmal rupture, we found that a large amount of blood was frequently present in the oval, funnel and daughter sac types of aneurysm, when S/N ratio was low, and when an underlying disease such as hypertension or diabetes was present. Conversely, a small amount of blood was present in the cylindrical type, when S/N ratio was high, and where there was no underlying disease.=20

  17. Large deviations

    CERN Document Server

    Deuschel, Jean-Dominique; Deuschel, Jean-Dominique

    2001-01-01

    This is the second printing of the book first published in 1988. The first four chapters of the volume are based on lectures given by Stroock at MIT in 1987. They form an introduction to the basic ideas of the theory of large deviations and make a suitable package on which to base a semester-length course for advanced graduate students with a strong background in analysis and some probability theory. A large selection of exercises presents important material and many applications. The last two chapters present various non-uniform results (Chapter 5) and outline the analytic approach that allow

  18. Amounts of mercury in soil of some golf course sites

    Energy Technology Data Exchange (ETDEWEB)

    MacLean, A J; Stone, B; Cordukes, W E

    1973-01-01

    Mercurial compounds are widely used for controlling diseases of turfgrass of golf courses, but the fungicides are usually confined to the greens. Composite soil samples were obtained from three golf courses in the Ottawa and Ontario region of Canada. Samples from the turf and surface layer of soil were analyzed and high amounts of mercury were found. The soil of No.I course was a sand; No.II was a sandy loam in the surface and a loam below; and No. III was a loam in the surface layer and a clay loam below. The pH of the surface layer was 6.4 in No. I, 7.5 in No. II, and 6.0 in No. III. The amounts of Hg in the turf were high near the green but they decreased with distance. Fairway III contained the highest amounts of Hg and there was evidence of it leaching to a depth of 90 cm at the edge of the green. The particularly high amounts of Hg in no III were in accord with the liberal use of mercurial fungicides on this course in the period 1912-64. The leaching of Hg depends on amounts of organic matter and the clay in the soil.

  19. Eye Involvement in TSC

    Science.gov (United States)

    ... eye involvement. Nonretinal and Retinal Eye Findings Facial angiofibromas may involve the eyelids of individuals with TSC, ... the hamartomas have many blood vessels (as are angiofibromas of the skin). Less than half of the ...

  20. Increasing the amount of payment to research subjects

    Science.gov (United States)

    Resnick, DB

    2014-01-01

    This article discusses some ethical issues that can arise when researchers decide to increase the amount of payment offered to research subjects to boost enrollment. Would increasing the amount of payment be unfair to subjects who have already consented to participate in the study? This article considers how five different models of payment—the free market model, the wage payment model, the reimbursement model, the appreciation model, and the fair benefits model—would approach this issue. The article also considers several practical problems related to changing the amount of payment, including determining whether there is enough money in the budget to offer additional payments to subjects who have already enrolled, ascertaining how difficult it will be to re-contact subjects, and developing a plan of action for responding to subjects who find out they are receiving less money and demand an explanation. PMID:18757614

  1. Neuronal involvement in cisplatin neuropathy

    DEFF Research Database (Denmark)

    Krarup-Hansen, A; Helweg-Larsen, Susanne Elisabeth; Schmalbruch, H

    2007-01-01

    of large dorsal root ganglion cells. Motor conduction studies, autonomic function and warm and cold temperature sensation remained unchanged at all doses of cisplatin treatment. The results of these studies are consistent with degeneration of large sensory neurons whereas there was no evidence of distal......Although it is well known that cisplatin causes a sensory neuropathy, the primary site of involvement is not established. The clinical symptoms localized in a stocking-glove distribution may be explained by a length dependent neuronopathy or by a distal axonopathy. To study whether the whole neuron...

  2. Organizing Patient Involvement

    DEFF Research Database (Denmark)

    Brehm Johansen, Mette

    hospitals. During the last 25 years, patient involvement and quality improvement have become connected in Danish healthcare policy. However, the ideal of involving patients in quality improvement is described in very general terms and with only few specific expectations of how it is to be carried out...... in practice, as I show in the thesis. In the patient involvement literature, the difficulties of getting patient involvement in quality improvement to have in an impact on the planning and development of healthcare services is, for example, ascribed to conceptual vagueness of patient involvement, differences...... in perspectives, values and understandings between patients and healthcare professionals, or the lack of managerial attention and prioritization....

  3. Epiphyseal involvement in unicameral bone cysts

    International Nuclear Information System (INIS)

    Capanna, R.; Ruggieri, P.; Biagini, R.; Horn, J. van

    1986-01-01

    Twelve patients are reported in whom a unicameral bone cyst was found to involve the epiphysis or apophysis across an open growth plate. Nine patients showed pathologic fracture. In four patients a growth disturbance was found. A varying amount of varus angulation was present in most cases. No patient had functional impairment. (orig.)

  4. Epiphyseal involvement in unicameral bone cysts

    Energy Technology Data Exchange (ETDEWEB)

    Capanna, R.; Ruggieri, P.; Biagini, R.; Horn, J. van

    1986-08-01

    Twelve patients are reported in whom a unicameral bone cyst was found to involve the epiphysis or apophysis across an open growth plate. Nine patients showed pathologic fracture. In four patients a growth disturbance was found. A varying amount of varus angulation was present in most cases. No patient had functional impairment.

  5. Modelling financial markets with agents competing on different time scales and with different amount of information

    Science.gov (United States)

    Wohlmuth, Johannes; Andersen, Jørgen Vitting

    2006-05-01

    We use agent-based models to study the competition among investors who use trading strategies with different amount of information and with different time scales. We find that mixing agents that trade on the same time scale but with different amount of information has a stabilizing impact on the large and extreme fluctuations of the market. Traders with the most information are found to be more likely to arbitrage traders who use less information in the decision making. On the other hand, introducing investors who act on two different time scales has a destabilizing effect on the large and extreme price movements, increasing the volatility of the market. Closeness in time scale used in the decision making is found to facilitate the creation of local trends. The larger the overlap in commonly shared information the more the traders in a mixed system with different time scales are found to profit from the presence of traders acting at another time scale than themselves.

  6. An experimental test of the habitat-amount hypothesis for saproxylic beetles in a forested region.

    Science.gov (United States)

    Seibold, Sebastian; Bässler, Claus; Brandl, Roland; Fahrig, Lenore; Förster, Bernhard; Heurich, Marco; Hothorn, Torsten; Scheipl, Fabian; Thorn, Simon; Müller, Jörg

    2017-06-01

    The habitat-amount hypothesis challenges traditional concepts that explain species richness within habitats, such as the habitat-patch hypothesis, where species number is a function of patch size and patch isolation. It posits that effects of patch size and patch isolation are driven by effects of sample area, and thus that the number of species at a site is basically a function of the total habitat amount surrounding this site. We tested the habitat-amount hypothesis for saproxylic beetles and their habitat of dead wood by using an experiment comprising 190 plots with manipulated patch sizes situated in a forested region with a high variation in habitat amount (i.e., density of dead trees in the surrounding landscape). Although dead wood is a spatio-temporally dynamic habitat, saproxylic insects have life cycles shorter than the time needed for habitat turnover and they closely track their resource. Patch size was manipulated by adding various amounts of downed dead wood to the plots (~800 m³ in total); dead trees in the surrounding landscape (~240 km 2 ) were identified using airborne laser scanning (light detection and ranging). Over 3 yr, 477 saproxylic species (101,416 individuals) were recorded. Considering 20-1,000 m radii around the patches, local landscapes were identified as having a radius of 40-120 m. Both patch size and habitat amount in the local landscapes independently affected species numbers without a significant interaction effect, hence refuting the island effect. Species accumulation curves relative to cumulative patch size were not consistent with either the habitat-patch hypothesis or the habitat-amount hypothesis: several small dead-wood patches held more species than a single large patch with an amount of dead wood equal to the sum of that of the small patches. Our results indicate that conservation of saproxylic beetles in forested regions should primarily focus on increasing the overall amount of dead wood without considering its

  7. Enrichment and determination of small amounts of 90Sr/90Y in water samples

    International Nuclear Information System (INIS)

    Mundschenk, H.

    1979-01-01

    Small amounts of 90 Sr/ 90 Y can be concentrated from large volumes of surface water (100 l) by precipitation of the phosphates, using bentonite as adsorber matrix. In the case of samples containing no or nearly no suspended matter (tap water, ground water, sea water), the daughter 90 Y can be extracted directly by using filter beds impregnated with HDEHP. The applicability of both techniques is demonstrated under realistic conditions. (orig.) 891 HP/orig. 892 MKO [de

  8. 42 CFR 402.105 - Amount of penalty.

    Science.gov (United States)

    2010-10-01

    ... insurance benefit plans (§ 402.1(c)(21)). (b) $1,000. CMS or OIG may impose a penalty of not more than $1... 42 Public Health 2 2010-10-01 2010-10-01 false Amount of penalty. 402.105 Section 402.105 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL...

  9. 20 CFR 404.338 - Widow's and widower's benefits amounts.

    Science.gov (United States)

    2010-04-01

    ... benefit may change as explained in § 404.304. (c) Your monthly benefit will be reduced if the insured person chooses to receive old-age benefits before reaching full retirement age. If so, your benefit will... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Widow's and widower's benefits amounts. 404...

  10. 26 CFR 1.617-2 - Limitation on amount deductible.

    Science.gov (United States)

    2010-04-01

    ... 1.617-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Natural Resources § 1.617-2 Limitation on amount deductible. (a... 1967, 1968, 1969, and 1970 A had exploration costs of $80,000 all with respect to coal deposits located...

  11. 26 CFR 1.615-4 - Limitation of amount deductible.

    Science.gov (United States)

    2010-04-01

    ... 1.615-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Natural Resources § 1.615-4 Limitation of amount deductible. (a) Taxable... lease with respect to certain coal lands. A has deducted exploration expenditures under section 615 for...

  12. 42 CFR 493.649 - Methodology for determining fee amount.

    Science.gov (United States)

    2010-10-01

    ... fringe benefit costs to support the required number of State inspectors, management and direct support... full time equivalent employee. Included in this cost are salary and fringe benefit costs, necessary... 42 Public Health 5 2010-10-01 2010-10-01 false Methodology for determining fee amount. 493.649...

  13. 42 CFR 422.382 - Minimum net worth amount.

    Science.gov (United States)

    2010-10-01

    ... that CMS considers appropriate to reduce, control or eliminate start-up administrative costs. (b) After... section. (c) Calculation of the minimum net worth amount—(1) Cash requirement. (i) At the time of application, the organization must maintain at least $750,000 of the minimum net worth amount in cash or cash...

  14. 7 CFR 3550.63 - Maximum loan amount.

    Science.gov (United States)

    2010-01-01

    ... self-help housing will be calculated by adding the total of the market value of the lot (including... amount. Total secured indebtedness must not exceed the area loan limit or market value limitations... appraisal, tax monitoring fee, and the charge to establish an escrow account for taxes and insurance will...

  15. 41 CFR 105-56.029 - Offset amount.

    Science.gov (United States)

    2010-07-01

    ... Administration 56-SALARY OFFSET FOR INDEBTEDNESS OF FEDERAL EMPLOYEES TO THE UNITED STATES Centralized Salary... salary offset under this subpart is $100. (b) The amount offset from a salary payment under this subpart... otherwise resolved to the satisfaction of the creditor agency. ...

  16. 20 CFR 615.6 - Extended Benefits; weekly amount.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Extended Benefits; weekly amount. 615.6 Section 615.6 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR EXTENDED... compensation payable during such benefit year. (2) If the method in paragraph (a)(1)(iii) of this section is...

  17. 46 CFR 308.300 - Insured amount-application.

    Science.gov (United States)

    2010-10-01

    ... Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE Second Seamen's War Risk Insurance § 308.300 Insured amount—application. An applicant for Second Seamen's war risk insurance shall not state the amount of insurance desired, which shall be as provided in...

  18. 13 CFR 143.52 - Collection of amounts due.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Collection of amounts due. 143.52 Section 143.52 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION UNIFORM ADMINISTRATIVE... Government. If not paid within a reasonable period after demand, the Federal agency may reduce the debt by...

  19. 34 CFR 682.506 - Limitations on maximum loan amounts.

    Science.gov (United States)

    2010-07-01

    ... loan is intended less— (i) The student's estimated financial assistance; and (ii) The student's.... (b) The Secretary does not guarantee a Federal Consolidation loan in an amount greater than that required to discharge loans eligible for consolidation under § 682.100(a)(4). (Authority: 20 U.S.C. 1075...

  20. 7 CFR 3565.204 - Maximum loan amount.

    Science.gov (United States)

    2010-01-01

    ... project. The lender shall recommend to the Agency an adjustment in the loan amount if appropriate as a result of this review. (2) Where the project financing combines a guaranteed loan with Low-Income Housing Tax Credits or other Federal assistance, the project must conform to the policies regarding necessary...

  1. 9 CFR 89.1 - Amount of feed.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Amount of feed. 89.1 Section 89.1 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS STATEMENT OF POLICY UNDER THE...

  2. 29 CFR 530.303 - Considerations in determining amounts.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Considerations in determining amounts. 530.303 Section 530... REGULATIONS EMPLOYMENT OF HOMEWORKERS IN CERTAIN INDUSTRIES Civil Money Penalties § 530.303 Considerations in... representations; and (5) Exercise of due care. (b) An employer's financial inability to meet obligations under the...

  3. 76 FR 71554 - Civil Penalties; Notice of Adjusted Maximum Amounts

    Science.gov (United States)

    2011-11-18

    ... Substances Act (FHSA), and the Flammable Fabrics Act (FFA). The Improvement Act added civil penalty authority... penalty amounts authorized under the Consumer Product Safety Act, the Federal Hazardous Substances Act, and the Flammable Fabrics Act. On August 14, 2009, the Consumer Product Safety Improvement Act of 2008...

  4. 78 FR 4057 - Inflation Adjustment of Civil Money Penalty Amounts

    Science.gov (United States)

    2013-01-18

    ...] RIN 2501-AD59 Inflation Adjustment of Civil Money Penalty Amounts AGENCY: Office of the Secretary, HUD. ACTION: Final rule. SUMMARY: This final rule amends HUD's civil money penalty and civil penalty... outdated cross-reference in its civil money penalty regulations. DATES: Effective Date: February 19, 2013...

  5. AMOUNT TO EXPROPRIATION? AN ANALYSIS OF THE Agri SA

    African Journals Online (AJOL)

    Examiner

    then make an order for the payment against the defendant to the state of any amount .... The second point of criticism is found in a decision of the Australian High Court, .... system when it comes to distinguishing between deprivation and ...

  6. 47 CFR 54.403 - Lifeline support amount.

    Science.gov (United States)

    2010-10-01

    ... local exchange carrier serving the area in which the qualifying low-income consumer receives service, as... a qualifying low-income consumer's intrastate rate, if the carrier has received the non-federal... SERVICE Universal Service Support for Low-Income Consumers § 54.403 Lifeline support amount. (a) The...

  7. 26 CFR 1.1441-2 - Amounts subject to withholding.

    Science.gov (United States)

    2010-04-01

    ..., it shall apply only to obligations issued after December 31, 2000. (4) Securities lending... issue discount) described in section 871(i)(2)(A) or 881(d)); (3) Amounts described in § 1.1441-1(b)(4)(iv) (dealing with interest or original issue discount on certain short-term obligations described in...

  8. JOINT INVOLVEMENT IN SYPHILIS

    Directory of Open Access Journals (Sweden)

    T. I. Zlobina

    2016-01-01

    Full Text Available Joint involvement in syphilis has been considered as casuistry in recent years. At the same time, the high incidence of primary syphilis and the notified cases of late neurosyphilis may suggest that joint involvement in this disease is by no means always verified. Traditionally there are two forms of syphilitic arthritis: primary synovial (involving the articular membranes and sac and primary bone (involving the articular bones and cartilages ones. The paper describes the authors' clinical case of the primary bone form of articular syphilis in a 34-year-old man. 

  9. Neuro-economics in chicks: foraging choices based on amount, delay and cost.

    Science.gov (United States)

    Matsushima, Toshiya; Kawamori, Ai; Bem-Sojka, Tiaza

    2008-06-15

    Studies on the foraging choices are reviewed, with an emphasis on the neural representations of elementary factors of food (i.e., amount, delay and consumption time) in the avian brain. Domestic chicks serve as an ideal animal model in this respect, as they quickly associate cue colors with subsequently supplied food rewards, and their choices are quantitatively linked with the rewards. When a pair of such color cues was simultaneously presented, the trained chicks reliably made choices according to the profitability of food associated with each color. Two forebrain regions are involved in distinct aspects of choices; i.e., nucleus accumbens-medial striatum (Ac-MSt) and arcopallium intermedium (AI), an association area in the lateral forebrain. Localized lesions of Ac-MSt enhanced delay aversion, and the ablated chicks made impulsive choices of immediate reward more frequently than sham controls. On the other hand, lesions of AI enhanced consumption-time aversion, and the ablated chicks shifted their choices toward easily consumable reward with their impulsiveness unchanged; delay and consumption time are thus doubly dissociated. Furthermore, chicks showed distinct patterns of risk-sensitive choices depending on the factor that varied at trials. Risk aversion occurred when food amount varied, whereas consistent risk sensitivity was not found when the delay varied; amount and delay were not interchangeable. Choices are thus deviated from those predicted as optima. Instead, factors such as amount, delay and consumption time could be separately represented and processed to yield economically sub-optimal choices.

  10. Effect of increasing amounts of straw on pigs’ explorative behaviour

    DEFF Research Database (Denmark)

    Jensen, Margit Bak; Herskin, Mette S.; Forkman, Björn

    2015-01-01

    According to European legislation, pigs must have permanent access to sufficient quantity of materialto enable manipulation activities. However, few studies have quantified how much straw is needed tofulfil the requirements of growing pigs. We investigated the effect of increasing amount of straw...... on pigs’manipulation of the straw, and hypothesised that after a certain point increasing straw amount will nolonger increase oral manipulation further. From 30 to 80 kg live weight, pigs were housed in 90 groups of18 pigs in pens (5.48 m × 2.48 m) with partly slatted concrete floor and daily provided...... with the percentage ofpigs manipulating straw simultaneously. This was recorded in three 1-h intervals (1 h before and 1 h afterstraw allocation in the morning, as well as from 17 to 18 h in the afternoon). With increasing quantity ofstraw provided, we found a curvilinear (P increase in the time spent in oral...

  11. Amount of substance and the proposed redefinition of the mole

    Science.gov (United States)

    Milton, M. J. T.; Mills, I. M.

    2009-06-01

    There has been considerable discussion about the merits of redefining four of the base units of the SI, including the mole. In this paper, the options for implementing a new definition for the mole based on a fixed value for the Avogadro constant are discussed. They are placed in the context of the macroscopic nature of the quantity amount of substance and the opportunity to introduce a system for molar and atomic masses with unchanged values and consistent relative uncertainties.

  12. 44 CFR 11.78 - Computation of amount of award.

    Science.gov (United States)

    2010-10-01

    ... acquired by purchase or exchange), and there will be no allowance for replacement cost or for appreciation... this section. (b) Depreciation in value is determined by considering the type of article involved, its...

  13. Material-Point Analysis of Large-Strain Problems

    DEFF Research Database (Denmark)

    Andersen, Søren

    The aim of this thesis is to apply and improve the material-point method for modelling of geotechnical problems. One of the geotechnical phenomena that is a subject of active research is the study of landslides. A large amount of research is focused on determining when slopes become unstable. Hence......, it is possible to predict if a certain slope is stable using commercial finite element or finite difference software such as PLAXIS, ABAQUS or FLAC. However, the dynamics during a landslide are less explored. The material-point method (MPM) is a novel numerical method aimed at analysing problems involving...... materials subjected to large strains in a dynamical time–space domain. This thesis explores the material-point method with the specific aim of improving the performance for geotechnical problems. Large-strain geotechnical problems such as landslides pose a major challenge to model numerically. Employing...

  14. Parent Involvement Handbook.

    Science.gov (United States)

    Caplan, Arna

    This handbook on parent involvement, designed to be used with preschool programs, was developed by the Jefferson County Public Schools in Lakewood, Colorado. Included are: (1) a general statement about parent involvement in an early childhood program, (2) a description of the Jefferson County Early Childhood Program, (3) a description of the…

  15. The Involved Ostrich

    DEFF Research Database (Denmark)

    Davies, Andrea; Dobscha, Susan; Geiger, Susi

    2008-01-01

    that the transition into parenthood can be difficult for men due to their lack of a physical connection to the pregnancy, a perception that the baby industry is not designed for them, the continuance of male stereotypes in the media, and also the time available to men to become involved in consumption activities......-natal data. Data revealed that men, according to their partner’s perceptions, used consumption as a virtual umbilical cord, although levels of consumption involvement varied from co-involvement for most purchases, to limited involvement, and/or involvement for ‘large’ items, particularly travel systems...... and technical items. This research also revealed that men partook in highly masculinized forms of “nesting,” and in general shunned pregnancy book reading; although some did engage in “research” activities such as searching the internet for product safety information. We conclude from this study...

  16. Socioeconomic Status Moderates Genetic and Environmental Effects on the Amount of Alcohol Use

    Science.gov (United States)

    Hamdi, Nayla R; Krueger, Robert F.; South, Susan C.

    2015-01-01

    Background Much is unknown about the relationship between socioeconomic status (SES) and alcohol use, including the means by which SES may influence risk for alcohol use. Methods Using a sample of 672 twin pairs (aged 25–74) derived from the MacArthur Foundation Survey of Midlife Development in the United States (MIDUS), the present study examined whether SES, measured by household income and educational attainment, moderates genetic and environmental influences on three indices of alcohol use: amount used, frequency of use, and problem use. Results We found significant moderation for amount of alcohol used. Specifically, genetic effects were greater in low-SES conditions, shared environmental effects (i.e., environmental effects that enhance the similarity of twins from the same families) tended to increase in high-SES conditions, and non-shared environmental effects (i.e., environmental effects that distinguish twins) tended to decrease with SES. This pattern of results was found for both income and education, and it largely replicated at a second wave of assessment spaced nine years after the first. There was virtually no evidence of moderation for either frequency of alcohol use or alcohol problems. Conclusions Our findings indicate that genetic and environmental influences on drinking amount vary as a function of the broader SES context, whereas the etiologies of other drinking phenomena are less affected by this context. Efforts to find the causes underlying the amount of alcohol used are likely to be more successful if such contextual information is taken into account. PMID:25778493

  17. Socioeconomic status moderates genetic and environmental effects on the amount of alcohol use.

    Science.gov (United States)

    Hamdi, Nayla R; Krueger, Robert F; South, Susan C

    2015-04-01

    Much is unknown about the relationship between socioeconomic status (SES) and alcohol use, including the means by which SES may influence risk for alcohol use. Using a sample of 672 twin pairs (aged 25 to 74) derived from the MacArthur Foundation Survey of Midlife Development in the United States, this study examined whether SES, measured by household income and educational attainment, moderates genetic and environmental influences on 3 indices of alcohol use: amount used, frequency of use, and problem use. We found significant moderation for amount of alcohol used. Specifically, genetic effects were greater in low-SES conditions, shared environmental effects (i.e., environmental effects that enhance the similarity of twins from the same families) tended to increase in high-SES conditions, and nonshared environmental effects (i.e., environmental effects that distinguish twins) tended to decrease with SES. This pattern of results was found for both income and education, and it largely replicated at a second wave of assessment spaced 9 years after the first. There was virtually no evidence of moderation for either frequency of alcohol use or alcohol problems. Our findings indicate that genetic and environmental influences on drinking amount vary as a function of the broader SES context, whereas the etiologies of other drinking phenomena are less affected by this context. Efforts to find the causes underlying the amount of alcohol used are likely to be more successful if such contextual information is taken into account. Copyright © 2015 by the Research Society on Alcoholism.

  18. Influence of social norms and palatability on amount consumed and food choice.

    Science.gov (United States)

    Pliner, Patricia; Mann, Nikki

    2004-04-01

    In two parallel studies, we examined the effect of social influence and palatability on amount consumed and on food choice. In Experiment 1, which looked at amount consumed, participants were provided with either palatable or unpalatable food; they were also given information about how much previous participants had eaten (large or small amounts) or were given no information. In the case of palatable food, participants ate more when led to believe that prior participants had eaten a great deal than when led to believe that prior participants had eaten small amounts or when provided with no information. This social-influence effect was not present when participants received unpalatable food. In Experiment 2, which looked at food choice, some participants learned that prior participants had chosen the palatable food, others learned that prior participants had chosen the unpalatable food, while still others received no information about prior participants' choices. The social-influence manipulation had no effect on participants' food choices; nearly all of them chose the palatable food. The results were discussed in the context of Churchfield's (1995) distinction between judgments about matters of fact and judgments about preferences. The results were also used to illustrate the importance of palatability as a determinant of eating behavior.

  19. Larger Bowl Size Increases the Amount of Cereal Children Request, Consume, and Waste

    NARCIS (Netherlands)

    Wansink, Brian; van Ittersum, Koert; Payne, Collin R.

    Objective To examine whether larger bowls bias children toward requesting more food from the adults who serve them. Study design Study 1 was a between-subject design involving 69 preschool-age children who were randomized to receive either a small (8 oz) or large (16 oz) cereal bowl and were asked

  20. Exploring the Amount and Type of Writing Instruction during Language Arts Instruction in Kindergarten Classrooms.

    Science.gov (United States)

    Puranik, Cynthia S; Al Otaiba, Stephanie; Sidler, Jessica Folsom; Greulich, Luana

    2014-02-01

    The objective of this exploratory investigation was to examine the nature of writing instruction in kindergarten classrooms and to describe student writing outcomes at the end of the school year. Participants for this study included 21 teachers and 238 kindergarten children from nine schools. Classroom teachers were videotaped once each in the fall and winter during the 90 minute instructional block for reading and language arts to examine time allocation and the types of writing instructional practices taking place in the kindergarten classrooms. Classroom observation of writing was divided into student-practice variables (activities in which students were observed practicing writing or writing independently) and teacher-instruction variables (activities in which the teacher was observed providing direct writing instruction). In addition, participants completed handwriting fluency, spelling, and writing tasks. Large variability was observed in the amount of writing instruction occurring in the classroom, the amount of time kindergarten teachers spent on writing and in the amount of time students spent writing. Marked variability was also observed in classroom practices both within and across schools and this fact was reflected in the large variability noted in kindergartners' writing performance.

  1. Exploring the Amount and Type of Writing Instruction during Language Arts Instruction in Kindergarten Classrooms

    Science.gov (United States)

    Puranik, Cynthia S.; Al Otaiba, Stephanie; Sidler, Jessica Folsom; Greulich, Luana

    2014-01-01

    The objective of this exploratory investigation was to examine the nature of writing instruction in kindergarten classrooms and to describe student writing outcomes at the end of the school year. Participants for this study included 21 teachers and 238 kindergarten children from nine schools. Classroom teachers were videotaped once each in the fall and winter during the 90 minute instructional block for reading and language arts to examine time allocation and the types of writing instructional practices taking place in the kindergarten classrooms. Classroom observation of writing was divided into student-practice variables (activities in which students were observed practicing writing or writing independently) and teacher-instruction variables (activities in which the teacher was observed providing direct writing instruction). In addition, participants completed handwriting fluency, spelling, and writing tasks. Large variability was observed in the amount of writing instruction occurring in the classroom, the amount of time kindergarten teachers spent on writing and in the amount of time students spent writing. Marked variability was also observed in classroom practices both within and across schools and this fact was reflected in the large variability noted in kindergartners’ writing performance. PMID:24578591

  2. Large ethics.

    Science.gov (United States)

    Chambers, David W

    2008-01-01

    This essay presents an alternative to the traditional view that ethics means judging individual behavior against standards of right and wrong. Instead, ethics is understood as creating ethical communities through the promises we make to each other. The "aim" of ethics is to demonstrate in our own behavior a credible willingness to work to create a mutually better world. The "game" of ethics then becomes searching for strategies that overlap with others' strategies so that we are all better for intending to act on a basis of reciprocal trust. This is a difficult process because we have partial, simultaneous, shifting, and inconsistent views of the world. But despite the reality that we each "frame" ethics in personal terms, it is still possible to create sufficient common understanding to prosper together. Large ethics does not make it a prerequisite for moral behavior that everyone adheres to a universally agreed set of ethical principles; all that is necessary is sufficient overlap in commitment to searching for better alternatives.

  3. Influence of ultrasonic energy on dispersion of aggregates and released amounts of organic matter and polyvalent cations

    Science.gov (United States)

    Kaiser, M.; Kleber, M.; Berhe, A. A.

    2010-12-01

    Aggregates play important roles in soil carbon storage and stabilization. Identification of scale-dependent mechanisms of soil aggregate formation and stability is necessary to predict and eventually manage the flow of carbon through terrestrial ecosystems. Application of ultrasonic energy is a common tool to disperse soil aggregates. In this study, we used ultra sonic energy (100 to 2000 J cm-3) to determine the amount of polyvalent cations and organic matter involved in aggregation processes in three arable and three forest soils that varied in soil mineral composition. To determine the amount of organic matter and cations released after application of different amount of ultrasonic energy, we removed the coarse fraction (>250 µm). The remaining residue (solid residue freeze dried before we analyzed the amounts of water-extracted organic carbon (OC), Fe, Al, Ca, Mn, and Mg in the filtrates. The extracted OM and solid residues were further characterized by Fourier Transformed Infra Red spectroscopy and Scanning Electron Microscopy. Our results show a linear increase in amount of dissolved OC with increasing amounts of ultra sonic energy up to 1500 J cm-3 indicating maximum dispersion of soil aggregates at this energy level independent from soil type or land use. In contrast to Mn, and Mg, the amounts of dissolved Ca, Fe, and Al increase with increasing ultra sonic energy up to 1500 J cm-3. At 1500 J cm-3, the absolute amounts of OC, Ca, Fe, and Al released were specific for each soil type, likely indicating differences in type of OM-mineral interactions involved in micro-scaled aggregation processes. The amounts of dissolved Fe, and Al released after an application of 1500 J cm-3 are not related to oxalate- and dithionite- extractable, or total Al content indicating less disintegration of pedogenic oxides or clay minerals due to high levels of ultrasonic energy.

  4. IDEA and Family Involvement

    Directory of Open Access Journals (Sweden)

    Mehmet Emin Öztürk

    2017-01-01

    Full Text Available Individuals with Disabilities Education Act (IDEA gives many rights to parents with special needs in terms of involvement and participation. Given the importance of family involvement in the special education process, and federal legislation that increasingly mandated and supported such involvement over time, considerable research has focused on the multiple ways that relationships between schools and families in the special education decision making process have played out. Educational professionals should create a positive climate for CLD families so that they feel more comfortable and therefore are able to participate more authentically and meaningfully.

  5. Amount and composition of rain failing at Rothamsted

    Energy Technology Data Exchange (ETDEWEB)

    Russell, E J; Richards, E H

    1919-01-01

    The monthly fluctuations in the ammoniacal concentration varies with rainfall, i.e., highest in spring; lowest in winter. The nitric nitrogen concentration fluctuated year by year and month by month in the same way as the ammoniacal nitrogen and the rainfall until 1910, since when there has been no simple relationship. The close relationship between the amounts of ammoniacal and nitric nitrogen suggests either a common origin or the production of nitric compounds from ammonia. Chlorine fluctuations closely follow the rainfall also. Since 1888, when the experiments began, to 1916, when they terminated, there has been a rise in the amounts of nitric nitrogen and of chlorine in the rain. In the case of chlorine a parallel series of determinations made at Cirencester over the same period shows a similar rise. There is no rise of ammonia but on the contrary a tendency to drop; the sum of ammoniacal and nitric nitrogen shows little change over the period. This seems to suggest that a former source of ammonia is now turning out nitric acid. It is possible that modern gas burners and grates tend to the formation of nitric oxides rather than of ammonia. Rain contains on an average 10 parts of dissolved oxygen per million, the amount being higher in winter than in summer: 66.4 lb per acre per annum was brought down during the two years over which the determinations extended. The marked difference in composition between summer and winter rainfall suggests that these may differ in their origin. The winter rain resembles Atlantic rain in its high chlorine and low ammonia and nitrate content; the summer rain is characterized by low chlorine but high ammonia and nitrate content, suggesting that it arises by evaporation of water from the soil and condensation at higher altitudes than in the case of winter rain.

  6. DEFERRED TAXES GENERATED BY THE CAPITALIZED INTERESTS IN THE AMOUNT

    Directory of Open Access Journals (Sweden)

    PALIU – POPA LUCIA

    2015-08-01

    Full Text Available According to the General Framework for preparing and presenting the financial statements elaborated by IASB, the utility of information is provided by attributes (qualitative features, such as: intelligibility, relevance, credibility and comparability. For being credible, the financial information shall be erroneous, shall not be biased or deforming the patrimony, and one of the elements representing and defining the information credibility is the prudency. Thus, the prudential accounting treatments affect, on the one hand, the accounting information relevance and credibility, and on the other hand, equally, both the producers as well as the users of the financial information, due to the economic consequences which are generated. From this perspective and considering that the implied economic agents are not neutral in terms of their option concerning the neutral accounting practices, prudent or aggressive, we opined that it is useful to conduct a study aiming the relevance of the accounting information related to the deferred taxes generated by the capitalized interests in the amount of the fix assets, recognizing the value of these taxes having as result the compliance with the principle of prudency within the accountancy. In this context, compared to the dominant accounting systems, respectively the continental system and the Anglo- Saxon system, within which the accounting information is characterized as legal, respectively addressed to the external users, especially to the investors, the conducted study aimed the following directions: the main differences between the provisions of the national, European, Anglo-Saxon accounting regulations and those of the international referential related to the prudency; the occurrence and evolution of the deferred taxes generated by the capitalized interests in the amount of the fix assets; informational benefits of the accounting prudency concerning the reflection of the deferred taxes established by the

  7. Optimum amount of an insurance sum in life insurance

    Directory of Open Access Journals (Sweden)

    Janez Balkovec

    2001-01-01

    Full Text Available Personal insurance represents one of the sources of personal social security as a category of personal property. How to get a proper life insurance is a frequently asked question. When insuring material objects (car, house..., the problem is usually not in the amount of the taken insurance. With life insurance (abstract goods, problems as such occur. In this paper, we wish to present a model that, according to the financial situation and the anticipated future, makes it possible to calculate the optimum insurance sum in life insurance.

  8. Cardiopulmonary involvement in Fabry's disease.

    Science.gov (United States)

    Koskenvuo, Juha W; Kantola, Ilkka M; Nuutila, Pirjo; Knuuti, Juhani; Parkkola, Riitta; Mononen, Ilkka; Hurme, Saija; Kalliokoski, Riikka; Viikari, Jorma S; Wendelin-Saarenhovi, Maria; Kiviniemi, Tuomas O; Hartiala, Jaakko J

    2010-04-01

    Fabry's disease is an X-linked lysosomal storage disease caused by deficiency of alpha-galactosidase A enzyme activity. Decreased enzyme activity leads to accumulation of glycosphingolipid in different tissues, including endothelial and smooth-muscle cells and cardiomyocytes. There is controversial data on cardiopulmonary involvement in Fabry's disease, because many reports are based on small and selected populations with Fabry's disease. Furthermore, the aetiology of cardiopulmonary symptoms in Fabry's disease is poorly understood. We studied cardiopulmonary involvement in seventeen patients with Fabry's disease (20-65 years, 6 men) using ECG, bicycle stress, cardiac magnetic resonance imaging, spirometry, diffusing capacity and pulmonary high-resolution computed tomography (HRCT) tests. Cardiopulmonary symptoms were compared to observed parameters in cardiopulmonary tests. Left ventricular hypertrophy (LVH) and reduced exercise capacity are the most apparent cardiac changes in both genders with Fabry's disease. ECG parameters were normal when excluding changes related to LVH. Spirometry showed mild reduction in vital capacity and forced expiratory volume in one second (FEV I), and mean values in diffusing capacity tests were within normal limits. Generally, only slight morphological pulmonary changes were detected using pulmonary HRCT, and they were not associated with changes in pulmonary function. The self-reported amount of pulmonary symptoms associated only with lower ejection fraction (P routine cardiopulmonary evaluation in Fabry's disease using echocardiography is maybe enough when integrated to counselling for aerobic exercise training.

  9. Parental Involvement in Education.

    Science.gov (United States)

    Blackstone, Tessa

    1979-01-01

    Arguments in favor of increased parental involvement, particularly in nursery education, are presented. Opposition to participation from parents and teachers is discussed and specific areas in which cooperation might be possible are suggested along with different levels of participation. (JMF)

  10. A Transmission-Cost-Based Model to Estimate the Amount of Market-Integrable Wind Resources

    DEFF Research Database (Denmark)

    Morales González, Juan Miguel; Pinson, Pierre; Madsen, Henrik

    2012-01-01

    are made to share the expenses in transmission derived from their integration, they may see the doors of electricity markets closed for not being competitive enough. This paper presents a model to decide the amount of wind resources that are economically exploitable at a given location from a transmission......In the pursuit of the large-scale integration of wind power production, it is imperative to evaluate plausible frictions among the stochastic nature of wind generation, electricity markets, and the investments in transmission required to accommodate larger amounts of wind. If wind producers......-cost perspective. This model accounts for the uncertain character of wind by using a modeling framework based on stochastic optimization, simulates market barriers by means of a bi-level structure, and considers the financial risk of investments in transmission through the conditional value-at-risk. The major...

  11. Amount, composition and seasonality of dissolved organic carbon and nitrogen export from agriculture in contrasting climates

    DEFF Research Database (Denmark)

    Graeber, Daniel; Meerhof, Mariana; Zwirnmann, Elke

    2014-01-01

    Agricultural catchments are potentially important but often neglected sources of dissolved organic matter (DOM), of which a large part is dissolved organic carbon (DOC) and nitrogen (DON). DOC is an important source of aquatic microbial respiration and DON may be an important source of nitrogen...... to aquatic ecosystems. However, there is still a lack of comprehensive studies on the amount, composition and seasonality of DOM export from agricultural catchments in different climates. The aim of our study was to assess the amount, composition and seasonality of DOM in a total of four streams in the wet......-temperate and subtropical climate of Denmark and Uruguay, respectively. In each climate, we investigated one stream with extensive agriculture (mostly pasture) and one stream with intensive agriculture (mostly intensively used arable land) in the catchment. We sampled each stream taking grab samples fortnightly for two...

  12. Separation and preconcentration trace amounts of gold by using modified organo nanoclay closite 15A

    Directory of Open Access Journals (Sweden)

    Sayed Zia Mohammadi

    2010-01-01

    Full Text Available The application of organo nanoclay 5-(4-dimethylamino-benzylidene rhodanine-immobilized as a new, easily prepared, and stable solid sorbent for preconcentration trace amounts of Au(III ions in aqueous solution is presented. The sorption of Au(III ions was quantitative in the pH range of 2-4, and quantitative desorption occurred instantaneously with 10.0 mL of a mixture containing 0.5 mol L-1 Na2S2O3 and KSCN. Various parameters, such as the effect of pH, breakthrough volume, extraction time, and interference of a large number of anions and cations have been studied. The proposed method has been applied for determination of trace amount of gold in water samples.

  13. Milk intake in kits: not only the total amount matters

    Directory of Open Access Journals (Sweden)

    Alberto Arnau Bonachera

    2017-06-01

    Full Text Available The aim of this work was to identify milk intake variation patterns in kits throughout lactation, to evaluate their permanent maternal component and their relationships with the performance of kits before and after weaning. To achieve this goal, we used 73 rabbit does, controlled between the 1st and the 4th lactation, which kindled 229 litters with a total of 2225 kits. The daily milk intake records per young rabbit were analysed using a principal component analysis (PCA. We found that 72.3% of the variability was explained by the first 3 principal components (PCs. PC1 explained 46.4% of the total variability, was associated with the total amount of milk intake during lactation and presented a repeatability of 0.27 (P0.05. This component was little related to performance traits. Therefore, it seems that milk plays 2 different roles at the beginning of feed intake; the most important would affect development of the kits and thus is related with high intake. The second one, for a given total amount of milk intake during lactation, would create a kind of competition between milk and feed intake at the end of lactation. The effects of both components still persist during the growing period and seem to be moderately affected by the mother.

  14. Measurements of mitochondrial spaces are affected by the amount of mitochondria used in the determinations

    International Nuclear Information System (INIS)

    Cohen, N.S.; Cheung, C.W.; Raijman, L.

    1987-01-01

    Mitochondrial (MITL) water spaces were determined by centrifugal filtration, using 3 H 2 O and 14 C-labelled sucrose, mannitol, inulin, and dextran. The volume (in μl/mg of MITL protein) of each of the spaces was inversely proportional to the amount of MIT (mg of protein) centrifuged. For every additional mg of MIT centrifuged, the total water space (in μl/mg of protein) decreased 0.62 μl, the sucrose space 0.50 μl, the intermembrane space 0.16 μl, and the matrix space 0.12 μl. For a given amount of MIT, the volume of each space was the same when centrifugation was done at 8000 and at 15,600g, and when the MIT were incubated with the markers for 15 sec to 5 min, indicating that sucrose, mannitol and inulin do not penetrate the matrix, nor dextran the intermembrane space, under the incubation and centrifugation conditions generally used to measure MITL spaces. They conclude that: (a) calculations of the concentration of compounds in the matrix or intermembrane space may contain large errors unless the same amount of MIT is used to measure MITL spaces and the compounds of interest; (b) large errors in the calculation of transport rates, proton-motive force, etc., may arise from errors originating as in (a) above; (c) disagreements found in the literature regarding, for example, the size of the sucrose space, may have arisen from the use of different amounts of MIT in different work

  15. DHA involvement in neurotransmission process

    Directory of Open Access Journals (Sweden)

    Vancassel Sylvie

    2007-05-01

    Full Text Available The very high enrichment of the nervous system in the polyunsaturated fatty acids, arachidonic (AA, 20: 4n-6 and docosahexaenoic acids (DHA, 22: 6n-3, is dependant of the dietary availability of their respective precursors, linoleic (18: 2n-6 and_-linolenic acids (18: 3n-3. Inadequate amounts of DHA in brain membranes have been linked to a wide variety of abnormalities ranging from visual acuity and learning irregularities, to psychopathologies. However, the molecular mechanisms involved remain unknown. Several years ago, we hypothesized that a modification of DHA contents of neuronal membranes by dietary modulation could change the neurotransmission function and then underlie inappropriate behavioural response. We showed that, in parallel to a severe loss of brain DHA concomitant to a compensatory substitution by 22:5n-6, the dietary lack of α-linolenic acid during development induced important changes in the release of neurotransmitters (dopamine, serotonin, acetylcholine in cerebral areas specifically involved in learning, memory and reward processes. Data suggested alteration of presynaptic storage process and dysregulations of reciprocal functional interactions between monoaminergic and cholinergic pathways. Moreover, we showed that recovery of these neurochemical changes was possible when the deficient diet was switched to a diet balanced in n-3 and n-6 PUFA before weaning. The next step is to understand the mechanism involved. Particularly, we focus on the study of the metabolic cooperation between the endothelial cell, the astrocyte and the neuron which regulate synaptic transmission.These works could contribute to the understanding of the link between some neuropsychiatric disorders and the metabolism of n-3 PUFA, through their action on neurotransmission.

  16. Augmented surgical amounts for intermittent exotropia to prevent recurrence

    Directory of Open Access Journals (Sweden)

    Hatice Arda

    2014-01-01

    Full Text Available Purpose: The purpose was to evaluate the results of bilateral lateral rectus (BLR recession which is based on augmented surgical amounts of classical surgical table of Parks′ for basic and pseudo-divergence excess type intermittent exotropia [X(T]. Materials and Methods: Patients with X(T operated by the same surgeon and followed-up for at least 6 months were included. Patients with prior surgery, neurobehavioral and musculoskeletal conditions, strabismus different from that mentioned above X(T were excluded. All the patients received BLR only. The amount of the recession was increased by the amount needed to correct 5 prism diopters (PD more X(T than what was measured. After the operation, 1 st week, 2 nd and 6 months measurements were recorded. The patients were grouped according to their 1 st week (3-7 days postoperative examination as: >10 PD esotropia (Group 1, ≤10 PD esotropia (Group 2, exotropia (Group 3, and orthotropic (Group 4, respectively. Final surgical outcomes were classified as "good" (≤10 PD exotropia and ≤5 PD esotropia, "recurrence" (>10 PD exotropia and "overcorrected" (>5 esotropia. Results: Thirty-seven patients were included. The mean age was 6.78 ± 2.87 years (range: 2-12 years. Mean preoperative deviation was 29.72 ± 8.07 PD (range: 15-45 PD at distance and 20.94 ± 11.65 PD (range: 10-45 PD at near (P < 0.0001. There were 21 (56.8% patients in Group 1, 9 (24.3% patients in Group 2, 1 (2.7% patient in Group 3 and 6 (16.2% patients in Group 4. Initial esotropia was achieved in 30 (30/37 of the patients. Twenty-eight of them had good results at the end of the 6 months. Overall "motor surgical" success rate was found to be 89.2% (33/37 patients, with 1 (2.7% overcorrection and 3 (8.1% recurrences at the end of the 6 months. Conclusion: This study demonstrated that early overcorrection of 10-20 PD after X(T surgery can achieve acceptable motor outcomes in the first 6 months postoperative period.

  17. Quantitative relationship between adsorbed amount of solute and solvent composition

    International Nuclear Information System (INIS)

    Wang Yan; Geng Xindu; Zebolsky, Don M.

    2003-01-01

    A new adsorption isotherm that relates the amount of solute adsorbed to the solvent concentration is proposed. The new equation is derived from Geng and Shi's stoichiometric displacement model for adsorption (SDM-A). The obtained equation may be simplified to an expression containing two parameters. The equation with two parameters, valid for low concentrations of solute, is a logarithmically linear relationship. The intercept contains a thermodynamic equilibrium constant of the solute displacing solvent from the adsorbent. The slope is the negative value of the stoichiometric displacement parameter (Z), the average total number of solvent molecules displaced from an active site on the adsorbent and from the solute. Tests with a homologous series of aromatic alcohols by frontal analysis in reversed phase liquid chromatography demonstrate that experimental results fit the equation well

  18. Late excretion of plutonium following acquisition of known amounts

    International Nuclear Information System (INIS)

    Rundo, J.

    1981-01-01

    The urinary and fecal excretion rates of plutonium 10,000 days after intravenous injection of known amounts are compared with the predictions of various models. Both Langham's and Durbin's equations underestimated the urinary excretion by about an order of magnitude; the observed fecal excretion rates were also higher than the predictions. The total excretion rate predicted by the ICRP model was in quite good agreement with the observed rate, but it overestimated it at early times ( 239 Pu of former Manhattan Project plutonium workers, as calculated from the measured urinary excretion an application of Langham's equation. In one of these subjects the urinary excretion rate started to increase at about 6000 days, reached a maximum at about 9500 days, and declined for the next 2700 days

  19. Kinetic Spectrophotometric Determination of Trace Amounts of Sulfide

    Energy Technology Data Exchange (ETDEWEB)

    Barzegar, Mohsen [Tarbiat Modarres University, Tehran (Iran, Islamic Republic of); Jabbari, Ali [K. N. Toosi University, Tehran (Iran, Islamic Republic of); Esmaeili, Majid [Razi University, Kermanshah (Iran, Islamic Republic of)

    2003-09-15

    A method for the determination of trace amount of sulfide based on the addition reaction of sulfide with methyl green at pH 7.5 and 25 .deg. C is described. The reaction is monitored spectrophotometrically by measuring the decrease in absorbance of the dyestuff at 637 nm by the initial rate and fixed time method. The calibration graph is linear in the range 30-1200 ppb. The theoretical limit of detection was 0.014 ppm. Seven replicate analysis of a sample solution containing 0.70 ppm sulfide gave a relative standard deviation of 1.5%. The interfering effects of various ions on sulfide determination have been reported and procedures for removal of interference have been described. The proposed method was applied successfully to the determination of sulfide in tap and wastewater samples.

  20. Kinetic Spectrophotometric Determination of Trace Amounts of Sulfide

    International Nuclear Information System (INIS)

    Barzegar, Mohsen; Jabbari, Ali; Esmaeili, Majid

    2003-01-01

    A method for the determination of trace amount of sulfide based on the addition reaction of sulfide with methyl green at pH 7.5 and 25 .deg. C is described. The reaction is monitored spectrophotometrically by measuring the decrease in absorbance of the dyestuff at 637 nm by the initial rate and fixed time method. The calibration graph is linear in the range 30-1200 ppb. The theoretical limit of detection was 0.014 ppm. Seven replicate analysis of a sample solution containing 0.70 ppm sulfide gave a relative standard deviation of 1.5%. The interfering effects of various ions on sulfide determination have been reported and procedures for removal of interference have been described. The proposed method was applied successfully to the determination of sulfide in tap and wastewater samples

  1. Diagnostic imaging of small amounts of pleural fluid: pleural effusion vs. physiologic pleural fluid.

    Science.gov (United States)

    Kocijancic, Igor

    2007-12-01

    The aim of this article is to present an overview of our 10 years clinical research work and early clinical experience with small pleural effusions. Small amounts of pleural fluid are severely difficult to identify with imaging methods (chest x-rays and ultrasound). Nevertheless, it may be an important finding, sometimes leading to a definitive diagnosis of pleural carcinomatosis, infection or other pathologic condition. Chest x-rays were used for many years for the diagnosis of small pleural effusions. Lateral decubitus chest radiographs represented a gold standard for imaging of small amounts of plural fluid for more than 80 years. In the last two decades, ultrasonography of pleural space became a leading real-time method for demonstrating small pleural effusions. Furthermore, the advent of sonographic technology actually enables detection of physiologic pleural fluid in some otherwise healthy individuals. In conclusion, new definitions of the key terms in the field of diagnostic imaging of small amounts of pleural fluid seem to be justified. We suggest that the term pleural fluid should determine physiologic pleural space condition while the term pleural effusion should only be used in the cases of pleural involvement or pleural illness.

  2. First-aid training in school: amount, content and hindrances.

    Science.gov (United States)

    Bakke, H K; Bakke, H K; Schwebs, R

    2017-11-01

    To increase knowledge and competence about first aid in the population, first-aid instruction is included in primary and secondary school curricula. This study aimed to establish how much time is spent on first-aid training, which first-aid measures are taught, and which factors prevent teachers from providing the quantity and quality of first-aid training that they wish to give. A questionnaire was distributed to teachers in physical education in primary and secondary schools and to teachers in vocational subjects in higher secondary schools. The teachers taught a median of two lessons in first aid per year. Cardiopulmonary resuscitation (CPR) was taught by 64% of teachers, free airway and recovery position by 69% and stopping severe bleeding by 51%. Recognising heart attack and stroke was taught by 25% and 23%, respectively. The main factors that the teachers perceived as limiting the amount and quality of first-aid training were insufficient learning objective specifications in the curriculum, too many other competence aims, lack of CPR mannequins and lack of training as first-aid instructors. Norwegian teachers provide an appreciable amount of first-aid training to their students. However, several potential life-saving measures are poorly covered. The curriculum needs to contain first aid but also should specify what first-aid measures to be taught. First-aid training of teachers should adequately prepare them to be first-aid instructors. © 2017 The Authors. Acta Anaesthesiologica Scandinavica published by John Wiley & Sons Ltd on behalf of Acta Anaesthesiologica Scandinavica Foundation.

  3. Choosing the right amount of healthcare information technologies investments.

    Science.gov (United States)

    Meyer, Rodolphe; Degoulet, Patrice

    2010-04-01

    Choosing and justifying the right amount of investment in healthcare information technologies (HITECH or HIT) in hospitals is an ever increasing challenge. Our objectives are to assess the financial impact of HIT on hospital outcome, and propose decision-helping tools that could be used to rationalize the distribution of hospital finances. We used a production function and microeconomic tools on data of 21 Paris university hospitals recorded from 1998 to 2006 to compute the elasticity coefficients of HIT versus non-HIT capital and labor as regards to hospital financial outcome and optimize the distribution of investments according to the productivity associated with each input. HIT inputs and non-HIT inputs both have a positive and significant impact on hospital production (elasticity coefficients respectively of 0.106 and 0.893; R(2) of 0.92). We forecast 2006 results from the 1998 to 2005 dataset with an accuracy of +0.61%. With the model used, the best proportion of HIT investments was estimated to be 10.6% of total input and this was predicted to lead to a total saving of 388 million Euros for the 2006 dataset. Considering HIT investment from the point of view of a global portfolio and applying econometric and microeconomic tools allow the required confidence level to be attained for choosing the right amount of HIT investments. It could also allow hospitals using these tools to make substantial savings, and help them forecast their choices for the following year for better HITECH governance in the current stimulation context. (c) 2010 Elsevier Ireland Ltd. All rights reserved.

  4. Using automated feeders to wean calves fed large amounts of milk according to their ability to eat solid feed.

    Science.gov (United States)

    de Passillé, Anne Marie; Rushen, Jeffrey

    2016-05-01

    Dairy calves weaned off milk at an early age show signs of hunger and can lose weight. We examined whether using automated feeders to wean calves according to individual voluntary solid feed intake reduced the effects of weaning. Female Holstein calves were housed in groups of 5 to 9. All calves were fed 12 L/d milk and ad libitum grain starter and hay from automated feeders immediately after grouping, and were allocated to 3 weaning strategies: (1) early-weaned (EW; n=14): weaning began on d 40, and milk allowance gradually decreased until weaning was complete on d 48; (2) late-weaned (LW; n=14): weaning began on d 80 and was completed on d 89; (3) weaned by starter intake (WSI; n=28): weaning began when calves consumed 200g/d of starter and was completed when the calves consumed 1,400g/d. Each day, the automated feeders recorded quantities of milk, starter, and hay eaten by all calves, as well as the frequency of visits to the milk feeder; we used unrewarded visit frequency as a sign of hunger. Body weights (BW) were recorded weekly. We estimated daily digestible energy (DE) intake for each calf based on the milk, hay, and starter consumed. Average daily gains (ADG) were expressed as percent of BW. For calves in WSI, weaning began at 54.7±18.9 d (mean ± SD) of age, the duration of weaning was 21.1±10.6 d, and weaning ended at 75.8±10.7 d of age. Both LW and WSI calves had better ADG from wk 3 to 13 than EW calves. Calves in the WSI group drank less milk and ate more starter than LW calves but had similar ADG. During the period of weaning, EW calves made more unrewarded visits to the milk feeder than LW and WSI calves. Three EW calves lost weight during weaning, whereas all LW and WSI calves gained weight. Calves differ greatly in when they begin to eat solid feed and how quickly they increase the intake in response to a decrease in milk allowance. An advantage of automated feeders is that calves can be weaned at variable ages depending on their ability and willingness to eat solid feed, which reduces signs of hunger and improves weight gains during weaning. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  5. Generating and distributing electricity economically and in large amounts for generations. Siemens - a synonym of electrical industry

    International Nuclear Information System (INIS)

    Feldenkirchen, W.

    1997-01-01

    The development of electrical engineering and the history of the Siemens company have been closely interrelated since their beginnings. Since the late 19th century, the electrical industry, by constantly extending its range of products, has turned into a sector of economy with an international reputation. Under the paradigm of assuming technological leadership, or co-leadership, in the development of electrical engineering world-wide, Siemens has had its share in this process. (orig.) [de

  6. Human eosinophils express, relative to other circulating leukocytes, large amounts of secretory 14-kD phospholipase A2

    NARCIS (Netherlands)

    Blom, M.; Tool, A. T.; Wever, P. C.; Wolbink, G. J.; Brouwer, M. C. [=Maria Clara; Calafat, J.; Egesten, A.; Knol, E. F.; Hack, C. E.; Roos, D.; Verhoeven, A. J.

    1998-01-01

    Human eosinophils perform several functions dependent on phospholipase A2 (PLA2) activity, most notably the synthesis of platelet-activating factor (PAF) and leukotriene C4 (LTC4). Several forms of PLA2 have been identified in mammalian cells. In the present study, the 14-kD, secretory form of PLA2

  7. Cardiovascular involvement in myositis

    DEFF Research Database (Denmark)

    Diederichsen, Louise P

    2017-01-01

    PURPOSE OF REVIEW: The purpose of this review is to provide an update on cardiovascular involvement in idiopathic inflammatory myopathy (IIM). Studies from the past 18 months are identified and reviewed. Finally, the clinical impact of these findings is discussed. RECENT FINDINGS: Epidemiological...... on cardiac magnetic resonance (CMR) imaging suggests that CMR should be considered as a potentially viable diagnostic tool to evaluate the possibility of silent myocardial inflammation in IIM with normal routine noninvasive evaluation. SUMMARY: Updated literature on cardiovascular involvement in IIM has...... identified an increased risk for subclinical and clinical cardiovascular disease in these rare inflammatory muscle diseases....

  8. Determination of micro amounts of samarium and europium by analogue derivative spectrophotometry

    International Nuclear Information System (INIS)

    Ishii, H.; Satoh, K.

    1982-01-01

    Derivative spectrophotometry using the analogue differentiation circuit was applied to the determination of samarium and europium at ppm levels. By measuring the second or the fourth derivative spectra of the characteristic absorption bands of both the rare earth ions around 400 nm, they can be determined directly and selectively in the presence of large amounts of most other rare earths without any prior separation. Further, aptly selecting conditions for the measurement of the derivative spectra, the simultaneous determination of both the rare earth elements was feasible. The principle and the characteristics of analogue derivative spectrophotometry are also described. (orig.) [de

  9. Reliability of large superconducting magnets through design

    International Nuclear Information System (INIS)

    Henning, C.D.

    1980-01-01

    As superconducting magnet systems grow larger and become the central component of major systems involving fusion, magnetohydrodynamics, and high-energy physics, their reliability must be commensurate with the enormous capital investment in the projects. Although the magnet may represent only 15% of the cost of a large system such as the Mirror Fusion Test Facility, its failure would be catastrophic to the entire investment. Effective quality control during construction is one method of ensuring success. However, if the design is unforgiving, even an inordinate amount of effort expended on quality control may be inadequate. Creative design is the most effective way of ensuring magnet reliability and providing a reasonable limit on the amount of quality control needed. For example, by subjecting the last drawing operation is superconductor manufacture to a stress larger than the magnet design stress, a 100% proof test is achieved; cabled conductors offer mechanical redundancy, as do some methods of conductor joining; ground-plane insulation should be multilayered to prevent arcs, and interturn and interlayer insulation spaced to be compatible with the self-extinguishing of arcs during quench voltages; electrical leads should be thermally protected; and guard vacuum spaces can be incorporated to control helium leaks. Many reliable design options are known to magnet designers. These options need to be documented and organized to produce a design guide. Eventually, standard procedures, safety factors, and design codes can lead to reliability in magnets comparable to that obtained in pressure vessels and other structures. Wihout such reliability, large-scale applications in major systems employing magnetic fusion energy, magnetohydrodynamics, or high-energy physics would present unacceptable economic risks

  10. Who Involves Whom?

    Science.gov (United States)

    Ward, Clifford

    1979-01-01

    The author reviews the development of a parents' group at the Bradford Grange School (Manchester, United Kingdom) for ESN (educationally subnormal) children. Problems with the initial parents' group are pointed out, successful approaches are considered, and the importance of parent involvement is stressed. (SBH)

  11. PATTERNS AND FACTORS INVOLVED

    African Journals Online (AJOL)

    Between 1*' of July 1996 and 30'h of June 2000 a total of 3583 patients were registered at the accident and emergency unit of Nnamdi. Azikiwe ... The case files of these were reviewed with a view to ascertaining the causes and factors involved in the deaths of these patients. The .... H.I.V/AIDS related complications 23 6.8.

  12. Large truck and bus crash facts, 2010.

    Science.gov (United States)

    2012-09-01

    This annual edition of Large Truck and Bus Crash Facts contains descriptive statistics about fatal, injury, and : property damage only crashes involving large trucks and buses in 2010. Selected crash statistics on passenger : vehicles are also presen...

  13. Large truck and bus crash facts, 2012.

    Science.gov (United States)

    2014-06-01

    This annual edition of Large Truck and Bus Crash Facts contains descriptive statistics about fatal, injury, and property damage only crashes involving large trucks and buses in 2012. Selected crash statistics on passenger vehicles are also presented ...

  14. Large truck and bus crash facts, 2013.

    Science.gov (United States)

    2015-04-01

    This annual edition of Large Truck and Bus Crash Facts contains descriptive statistics about fatal, injury, and property damage only crashes involving large trucks and buses in 2013. Selected crash statistics on passenger vehicles are also presented ...

  15. Large truck and bus crash facts, 2009.

    Science.gov (United States)

    2011-10-01

    This annual edition of Large Truck and Bus Crash Facts contains descriptive statistics about fatal, injury, and : property damage only crashes involving large trucks and buses in 2009. Selected crash statistics on passenger : vehicles are also presen...

  16. Large truck and bus crash facts, 2011.

    Science.gov (United States)

    2013-10-01

    This annual edition of Large Truck and Bus Crash Facts contains descriptive statistics about fatal, injury, and : property damage only crashes involving large trucks and buses in 2011. Selected crash statistics on passenger : vehicles are also presen...

  17. Consequences of Modification of Photosystem Stoichiometry and Amount in Cyanobacteria

    Energy Technology Data Exchange (ETDEWEB)

    Vermaas, Willem [Arizona State Univ., Tempe, AZ (United States)

    2016-12-13

    The proposed research seeks to address two interconnected, important questions that impact photosynthetic processes and that reflect key differences between the photosynthetic systems of cyanobacteria and plants or algae. The first question is what are the reasons and consequences of the high photosystem I / photosystem II (PS I/PS II) ratio in many cyanobacteria, vs. a ratio that is close to unity in many plants and algae. The corresponding hypothesis is that most of PS I functions in cyclic electron transport, and that reduction in PS I will result primarily in a shortage of ATP rather than reducing power. This hypothesis will be tested by reducing the amount of PS I by changing the promoter region of the psaAB operon in the cyanobacterium Synechocystis sp. PCC 6803 and generating a range of mutants with different PS I content and thereby different PS I/PS II ratios, with some of the mutants having a PS II/PS I ratio closer to that in plants. The resulting mutants will be probed in terms of their growth rates, electron transfer rates, and P700 redox kinetics. A second question relates to a Mehler-type reaction catalyzed by two flavoproteins, Flv1 and Flv3, that accept electrons from PS I and that potentially function as an electron safety valve leading to no useful purpose of the photosynthesis-generated electrons. The hypothesis to be tested is that Flv1 and Flv3 use the electrons for useful purposes such as cyclic electron flow around PS I. This hypothesis will be tested by analysis of a mutant strain lacking flv3, the gene for one of the flavoproteins. This research is important for a more detailed understanding of the consequences of photosystem stoichiometry and amounts in a living system. Such an understanding is critical for not only insights in the regulatory systems of the organism but also to guide the development of biological or bio-hybrid systems for solar energy conversion into fuels.

  18. Large Hadron Collider manual

    CERN Document Server

    Lavender, Gemma

    2018-01-01

    What is the universe made of? How did it start? This Manual tells the story of how physicists are seeking answers to these questions using the world’s largest particle smasher – the Large Hadron Collider – at the CERN laboratory on the Franco-Swiss border. Beginning with the first tentative steps taken to build the machine, the digestible text, supported by color photographs of the hardware involved, along with annotated schematic diagrams of the physics experiments, covers the particle accelerator’s greatest discoveries – from both the perspective of the writer and the scientists who work there. The Large Hadron Collider Manual is a full, comprehensive guide to the most famous, record-breaking physics experiment in the world, which continues to capture the public imagination as it provides new insight into the fundamental laws of nature.

  19. [Large vessel vasculitides].

    Science.gov (United States)

    Morović-Vergles, Jadranka; Puksić, Silva; Gracanin, Ana Gudelj

    2013-01-01

    Large vessel vasculitis includes Giant cell arteritis and Takayasu arteritis. Giant cell arteritis is the most common form of vasculitis affect patients aged 50 years or over. The diagnosis should be considered in older patients who present with new onset of headache, visual disturbance, polymyalgia rheumatica and/or fever unknown cause. Glucocorticoides remain the cornerstone of therapy. Takayasu arteritis is a chronic panarteritis of the aorta ant its major branches presenting commonly in young ages. Although all large arteries can be affected, the aorta, subclavian and carotid arteries are most commonly involved. The most common symptoms included upper extremity claudication, hypertension, pain over the carotid arteries (carotidynia), dizziness and visual disturbances. Early diagnosis and treatment has improved the outcome in patients with TA.

  20. Method for removing trace contaminants from multicurie amounts of 144Ce

    International Nuclear Information System (INIS)

    Wagner, J.A.; Kanapilly, G.M.

    1976-01-01

    Removal of contaminants from stock solutions of 144 Ce(III) was required for large quantities of 144 Ce prior to incorporation into fused aluminosilicate particles for inhalation toxicology studies. Since available procedures for purification of 144 Ce could not be readily adapted to our laboratory conditions and requirements, a simple procedure was developed to purify 144 Ce in multicurie quantities of 144 Ce(III). This procedure consists of separation of 144 Ce from contaminants by precipitation and filtrations at different pH. Its simplicity and efficacy in providing a stock solution that would readily exchange into montmorillonite clay was demonstrated when it was used during the preparation of large amounts of 144 Ce in fused aluminosilicate particles

  1. The amount of glacial erosion of the bedrock

    International Nuclear Information System (INIS)

    Paasse, Tore

    2004-11-01

    The purpose of this study is to estimate an upper bound for the average erosion of fresh bedrock that can reasonably be expected during a glacial period or a single glaciation. The study is based on the assumption that classic sediments, formed by Scandinavian ice erosion during the Quaternary period, still exist within the formerly glaciated area or its periphery. The volume of these sediments thus constitutes the maximum average glacial erosion of bedrock within this area. This volume is calculated by estimating the thickness of the minerogenic Quaternary from well data in Sweden and Denmark and from seismic measurements in adjacent sea areas. The average thickness of the Quaternary deposits and other reogolith in the investigated area was estimated to 16 m. Assuming that the whole volume is the result of glacial erosion of fresh bedrock this corresponds to 12 m depth. However, a great part of the sediments may consist of glacially redistributed Tertiary regolith. As the amount of Tertiary regolith is uncertain the estimated maximum average glacial erosion rate in fresh bedrock is uncertain, and assuming that the total sediment volume is the result of glacial erosion leads to an overestimation of the glacial erosion depth. Considering this, the average glacial erosion during a full glacial period has been estimated to between 0.2 m and 4 m. If the extremes in the made assumptions are excluded the glacial erosion during a glacial cycle can be estimated to about 1 m

  2. Titration of uranium trace amounts in waters environment

    International Nuclear Information System (INIS)

    Larabi-Gruet, N.; Ithurbide, A.; Poulesquen, A.; Beaucaire, C.; Peulon, S.; Chausse, A.

    2007-01-01

    In the framework of studies concerning the uranium migration in soils and rocks, it seems necessary to quantify the uranium(VI) dissolved in solution. In the environmental conditions, the uranium(VI) is present at trace amounts. The most adapted method to this study and easy to carry out is the Adsorptive Stripping Voltammetry. By addition of a compound (ligand) with a reducing and strong complexing power, the uranium(VI) present in solution is reduced into a U(VI)-ligand complex. This specie is then oxidized and adsorbed on the mercury droplet where an electrolytic pre-concentration of the element to determine the quantity of is carried out. At last, a cathodic re-dissolution of the specie adsorbed in the U(IV)-ligand complex is carried out. The chosen analytical method is the differential impulsional voltammetry. With this method, it is possible to quantify low electro-active species quantities (sensitivity ∼25 ppt (10 -10 mol.L -1 ) for the uranium). This titration method in solution has been optimized, at first, in a non complexing medium. Then, the uranium in solution has been titrated in media whose composition has been progressively complexed (additions of CO 3 2- , SO 4 2- , Cl - ..) for being at last representative of the environmental interstitial waters. At last, this study has been carried out too by ICP-MS (Inductively Coupled Plasma-Mass Spectrometry) in order to compare the analysis sensitivity of these two detection methods. (O.M.)

  3. The amount of glacial erosion of the bedrock

    Energy Technology Data Exchange (ETDEWEB)

    Paasse, Tore [Geological Survey of Sweden, Uppsala (Sweden)

    2004-11-01

    The purpose of this study is to estimate an upper bound for the average erosion of fresh bedrock that can reasonably be expected during a glacial period or a single glaciation. The study is based on the assumption that classic sediments, formed by Scandinavian ice erosion during the Quaternary period, still exist within the formerly glaciated area or its periphery. The volume of these sediments thus constitutes the maximum average glacial erosion of bedrock within this area. This volume is calculated by estimating the thickness of the minerogenic Quaternary from well data in Sweden and Denmark and from seismic measurements in adjacent sea areas. The average thickness of the Quaternary deposits and other reogolith in the investigated area was estimated to 16 m. Assuming that the whole volume is the result of glacial erosion of fresh bedrock this corresponds to 12 m depth. However, a great part of the sediments may consist of glacially redistributed Tertiary regolith. As the amount of Tertiary regolith is uncertain the estimated maximum average glacial erosion rate in fresh bedrock is uncertain, and assuming that the total sediment volume is the result of glacial erosion leads to an overestimation of the glacial erosion depth. Considering this, the average glacial erosion during a full glacial period has been estimated to between 0.2 m and 4 m. If the extremes in the made assumptions are excluded the glacial erosion during a glacial cycle can be estimated to about 1 m.

  4. Kinetic method of determination of rhodium trace amounts

    International Nuclear Information System (INIS)

    Kalinina, V.E.; Lyakushina, V.M.; Rybina, A.E.

    1978-01-01

    A catalytic action of rhodium compounds has been detected and studied in the reaction of copper (2) tellurate oxidation with hypobromite to ditelluratocuprate (3) in an alkaline medium. The relationships between the reaction rate and concentrations of copper, tellurate, and hypobromite have been established. The optimum concentrations of the used compounds have been found: Csub(Cu(2))=4x10 -5 g-ion/l; Csub(OHsup(-))=3.0 g-ion/l; Csub(Te)=1.4x10 -2 g-ion/l; Csub(NaBrO)=2.17x10 -3 M. It has been established for chloride, sulphate, and perchlorate solutions of rhodium (3) and (4) that the reaction sensitivity increases by 2-3-fold with a temperature rise from 25-60 deg C. The technique of determining rhodium traces has been developed based on its catalytic action. The low limit of determined rhodium amounts is about 10 -3 mkg/ml

  5. Supply of genetic information--amount, format, and frequency.

    Science.gov (United States)

    Misztal, I; Lawlor, T J

    1999-05-01

    The volume and complexity of genetic information is increasing because of new traits and better models. New traits may include reproduction, health, and carcass. More comprehensive models include the test day model in dairy cattle or a growth model in beef cattle. More complex models, which may include nonadditive effects such as inbreeding and dominance, also provide additional information. The amount of information per animal may increase drastically if DNA marker typing becomes routine and quantitative trait loci information is utilized. In many industries, evaluations are run more frequently. They result in faster genetic progress and improved management and marketing opportunities but also in extra costs and information overload. Adopting new technology and making some organizational changes can help realize all the added benefits of the improvements to the genetic evaluation systems at an acceptable cost. Continuous genetic evaluation, in which new records are accepted and breeding values are updated continuously, will relieve time pressures. An online mating system with access to both genetic and marketing information can result in mating recommendations customized for each user. Such a system could utilize inbreeding and dominance information that cannot efficiently be accommodated in the current sire summaries or off-line mating programs. The new systems will require a new organizational approach in which the task of scientists and technicians will not be simply running the evaluations but also providing the research, design, supervision, and maintenance required in the entire system of evaluation, decision making, and distribution.

  6. Large-scale solar purchasing

    International Nuclear Information System (INIS)

    1999-01-01

    The principal objective of the project was to participate in the definition of a new IEA task concerning solar procurement (''the Task'') and to assess whether involvement in the task would be in the interest of the UK active solar heating industry. The project also aimed to assess the importance of large scale solar purchasing to UK active solar heating market development and to evaluate the level of interest in large scale solar purchasing amongst potential large scale purchasers (in particular housing associations and housing developers). A further aim of the project was to consider means of stimulating large scale active solar heating purchasing activity within the UK. (author)

  7. Microorganisms involved in MIC

    Energy Technology Data Exchange (ETDEWEB)

    Sorensen, K. [Danish Technological Institute (Denmark)

    2011-07-01

    Microbiologically influenced corrosion (MIC) is a widespread problem that is difficult to detect and assess because of its complex mechanism. This paper presents the involvement of microorganisms in MIC. Some of the mechanisms that cause MIC include hydrogen consumption, production of acids, anode-cathode formation and electron shuttling. A classic bio-corrosive microorganism in the oil and gas industry is sulphate-reducing prokaryotes (SRP). Methanogens also increase corrosion rates in metals. Some of the phylogenetic orders detected while studying SRP and methanogens are archaeoglobales, clostridiales, methanosarcinales and methanothermococcus. There were some implications, such as growth of SRP not being correlated with growth of methanogens; methanogens were included in MIC risk assessment. A few examples are used to display how microorganisms are involved in topside corrosion and microbial community in producing wells. From the study, it can be concluded that, MIC risk assessment includes system data and empirical knowledge of the distribution and number of microorganisms in the system.

  8. Involved Node Radiation Therapy

    DEFF Research Database (Denmark)

    Maraldo, Maja V; Aznar, Marianne C; Vogelius, Ivan R

    2012-01-01

    PURPOSE: The involved node radiation therapy (INRT) strategy was introduced for patients with Hodgkin lymphoma (HL) to reduce the risk of late effects. With INRT, only the originally involved lymph nodes are irradiated. We present treatment outcome in a retrospective analysis using this strategy...... to 36 Gy). Patients attended regular follow-up visits until 5 years after therapy. RESULTS: The 4-year freedom from disease progression was 96.4% (95% confidence interval: 92.4%-100.4%), median follow-up of 50 months (range: 4-71 months). Three relapses occurred: 2 within the previous radiation field......, and 1 in a previously uninvolved region. The 4-year overall survival was 94% (95% confidence interval: 88.8%-99.1%), median follow-up of 58 months (range: 4-91 months). Early radiation therapy toxicity was limited to grade 1 (23.4%) and grade 2 (13.8%). During follow-up, 8 patients died, none from HL, 7...

  9. Reactors also involve people

    International Nuclear Information System (INIS)

    Hurt, H.B.

    1975-01-01

    As the nuclear industry develops it is to be hoped that high quality occupational health programs will evolve along with other sound operational procedures and practices. The immediate involvement of occupational health personnel may well afford a safety factor which will minimize the likelihood of either the selection of personnel not adequate for the full responsibilities of their work or the continuation in responsible positions of personnel who develop handicaps of either a physical or mental nature

  10. Involvement through photography.

    Science.gov (United States)

    Takai, J

    2016-12-01

    As a photographer living in Tokyo, I have been visiting Suetsugi village regularly to take photographs and show the printed photographs to the residents. What is the role of photography? What does it mean to be involved in the life of Suetsugi through photography? This article discusses some of the answers to these questions 5 years after the accident at Fukushima Daiichi nuclear power plant.

  11. Getting involved in research.

    Science.gov (United States)

    Banner, Davina; Grant, Lyle G

    2011-01-01

    The need for quality nursing research to promote evidence-based practice and optimize patient care is well recognized. This is particularly pertinent in cardiovascular nursing, where cardiovascular disease continues to be the leading cause of morbidity and mortality worldwide (World Health Organization, 2007). Across the spectrum of academic, clinical, and health care administration nursing roles, research remains fundamental to bridging theory, practice, and education (LoBiondo-Wood, Haber, Cameron, & Singh, 2009). Despite recognition of the importance of nursing research, the gap between research and practice continues to be an ongoing issue (Funk, Tornquist, & Champagne, 1995; Pettengill, Gillies, & Clark, 1994; Rizzuto, Bostrom, Suterm, & Chenitz, 1994; Rolfe, 1998). Nurses are appropriately situated to contribute to research that improves clinical outcomes and health service delivery. However, the majority of nurses in clinical practice do not have a significant research component structured into their nursing role. In this research column, the authors outline the importance of nurses being engaged in research and present some different levels of involvement that nurses may assume. A continuum of nursing research involvement includes asking researchable questions, being a savvy consumer of research evidence, finding your own level of research involvement, and aspiring to lead.

  12. The Vital Minimum Amount of Drinking Water Required in Ecuador

    Directory of Open Access Journals (Sweden)

    Andrés Martínez Moscoso

    2018-02-01

    Full Text Available In 2017, the government of Ecuador established the minimum quantity of water required to be provided for free by drinking water utilities. Ecuador recognized the access to water as a fundamental human right because it guarantees the good living, known as “Sumak kawsay”, an indigenous Andean concept, in the Ecuadorian Constitution. This represents a novel approach to water rights in the world, as it is the first attempt to establish a minimum quantity of water under a constitutional guarantee by legislation, rather than regulation or judicial decision. However, this novel legislative approach raises the question of how this minimum amount of free water will impact the most vulnerable members of the Ecuadorian community. This paper provides the results of the first comprehensive research of the minimum required water provision in Ecuador. In order to measure the impact on the income of households, we built a methodology integrating: doctrinaire analyses, normative studies, and economic analyses. According to the Ecuadorian legislation, over-consumption of raw water generates additional costs that must be paid by water companies to the central government. In that regard, there is an inevitable relationship between the efficiency of the service and those additional costs. Efficiency, on this case, is the capacity of water companies (public or private to provide water services at an adequate price, observing the following parameters: quantity, quality and sufficiency. Our research found that with this legislation in three Ecuadorian local governments (Cuenca, Gualaceo and Suscal, the most vulnerable households (i.e., low-income and/or indigenous households will be affected the most. This means that and those families will spend the most part of their income on water services otherwise they would have to reduce their water consumption.

  13. Acetamiprid Accumulates in Different Amounts in Murine Brain Regions

    Directory of Open Access Journals (Sweden)

    Hayato Terayama

    2016-09-01

    Full Text Available Neonicotinoids such as acetamiprid (ACE belong to a new and widely used single class of pesticides. Neonicotinoids mimic the chemical structure of nicotine and share agonist activity with the nicotine acetylcholine receptor (nAchR. Neonicotinoids are widely considered to be safe in humans; however, they have recently been implicated in a number of human health disorders. A wide range of musculoskeletal and neuromuscular disorders associated with high doses of neonicotinoids administered to animals have also been reported. Consequently, we used a mouse model to investigate the response of the central nervous system to ACE treatment. Our results show that exposure to ACE-containing water for three or seven days (decuple and centuple of no observable adverse effect level (NOAEL/day caused a decrease in body weight in 10-week old A/JJmsSlc (A/J mice. However, the treatments did not affect brain histology or expression of CD34. ACE concentrations were significantly higher in the midbrain of ACE-treated mice than that of the normal and vehicle groups. Expression levels of α7, α4, and β2 nAChRs were found to be low in the olfactory bulb and midbrain of normal mice. Furthermore, in the experimental group (centuple ACE-containing water for seven days, β2 nAChR expression decreased in many brain regions. Information regarding the amount of accumulated ACE and expression levels of the acetylcholine receptor in each region of the brain is important for understanding any clinical symptoms that may be associated with ACE exposure.

  14. Muscle glycogen storage after different amounts of carbohydrate ingestion.

    Science.gov (United States)

    Ivy, J L; Lee, M C; Brozinick, J T; Reed, M J

    1988-11-01

    The purpose of this study was to determine whether the rate of muscle glycogen storage could be enhanced during the initial 4-h period postexercise by substantially increasing the amount of the carbohydrate consumed. Eight subjects cycled for 2 h on three separate occasions to deplete their muscle glycogen stores. Immediately and 2 h after exercise they consumed either 0 (P), 1.5 (L), or 3.0 g glucose/kg body wt (H) from a 50% glucose polymer solution. Blood samples were drawn from an antecubital vein before exercise, during exercise, and throughout recovery. Muscle biopsies were taken from the vastus lateralis immediately, 2 h, and 4 h after exercise. Blood glucose and insulin declined significantly during exercise in each of the three treatments. They remained below the preexercise concentrations during recovery in the P treatment but increased significantly above the preexercise concentrations during the L and H treatments. By the end of the 4 h-recovery period, blood glucose and insulin were still significantly above the preexercise concentrations in both treatments. Muscle glycogen storage was significantly increased above the basal rate (P, 0.5 mumol.g wet wt-1.h-1) after ingestion of either glucose polymer supplement. The rates of muscle glycogen storage, however, were not different between the L and H treatments during the first 2 h (L, 5.2 +/- 0.9 vs. H, 5.8 +/- 0.7 mumol.g wet wt-1.h-1) or the second 2 h of recovery (L, 4.0 +/- 0.9 vs. H, 4.5 +/- 0.6 mumol.g wet wt-1. h-1).(ABSTRACT TRUNCATED AT 250 WORDS)

  15. Involvement Without Participation?

    DEFF Research Database (Denmark)

    Olsén, Peter

    2012-01-01

    The article presents a case study of a knowledge-intensive company that launched a 2-year project to improve their psychosocial working environment. All parties agreed on the project, and the methods used aimed to promote the involvement of the employees. Surprisingly, the psychosocial working...... environment did not improve; on the contrary, it deteriorated. The article highlights cultural and structural obstacles to the process, including an inadequate understanding of organisational learning and a narrow focus on market and competition. The endeavours did not consistently increase delegation...

  16. Divisia amount and price index for energy consumption

    International Nuclear Information System (INIS)

    Bentzen, J.

    1993-01-01

    In connection with the calculation of total energy consumption related to aggregation of the individual fuel's combustion values, an alternative to Btu aggregation (combustion value measurement), designated the ''Divisia index'', is presented. This represents an economic measure for energy consumption. The Divisia index is demonstrated in relation to total national energy consumption and total energy consumption within the Danish housing sector and also with regard to the estimation of price and income elasticity within energy demand. It is only possible to utilize the Divisia index in relation to the last 20 years, which is the period where energy consumption has stagnated. The question of possible irreversible effects on energy consumption caused by large variations in energy prices is discussed. It is suggested that the reaction to a fall in prices is different and less significant than is the case with price rises. In the long term, results point at a reasonably high price elasticity within energy demand. (AB) (22 refs.)

  17. Neutron Damage in Steels Containing Small Amounts of Boron

    Energy Technology Data Exchange (ETDEWEB)

    Myers, H P

    1961-05-15

    Certain low alloy steels contain small amounts (0.003 to 0.007 w/o) of boron which element contributes to the development of the air hardening properties of these steels. Such steels appear attractive for reactor pressure vessel construction but the question arises whether they will, due to the (n,{alpha}) reaction in boron, be more susceptible to neutron radiation damage than other steels which do not contain boron. We have attempted to estimate the importance of damage arising through boron fission relative to that caused by fast neutrons by assuming that the two sources of damage will be proportional to the numbers of displaced atoms produced in the two processes when no annealing or re combination of defects occurs. Within the approximations used we conclude that in a neutron spectrum which may be represented by an equivalent thermal flux {phi}{sub t} and an equivalent fast flux at 1 MeV of {phi}{sub f}, then D, the ratio of damage to boron fission to that caused by fast neutrons, is D = 4.5 x 10{sup -2} {phi}{sub t}/{phi}{sub f} (for 0. 003 w/o B). For the conditions at the inside of the reactor tank to R3 this would imply D = 1.2 x 10{sup -2} , i.e. if the R3 tank were built with a steel containing 0.003 w/o B then damage due to boron fission would be only {approx} 1 % of that caused by fast neutrons. Further problems with such steels as here discussed are the probability of embrittlement due to the introduction of boron fission fragments lithium and helium and the possibility of a radiation enhanced diffusion of boron which might lead to accentuated slow strain rate embrittlement. We argue that none of these problems should arise. It is concluded that a constructional steel containing 0.003 to 0.007 w/o B should not on this account be more susceptible to radiation damage than other non boron containing steels.

  18. Involvement in Physical Activity

    Directory of Open Access Journals (Sweden)

    James Gavin

    2013-04-01

    Full Text Available A total of 1,096 adolescents participated in 123 focus groups regarding the perceived outcomes of their involvement in sports and physical activity (PA. The groups, segmented by grade level, sex, and school types, were conducted in both public and private high schools in Montreal, Quebec. We sought to understand, through the participants’ own words, their perception of the outcome matrix of involvement in sports and PA. Focus group questions emphasized changes that adolescents associated with such engagement. In particular, participants were asked how sports and PA might influence behaviors, emotional states, personal characteristics, and other outcomes. Twelve themes were identified in the responses: Positive Health and Physical Changes (18.5%, Activity-Related Positive Emotions (15.6%, and Personal Learning (11.3% were most prevalent in the discussions. A cluster of deeper personal changes thematically described as Self-Identity, Autonomy, and Positive Character Development accounted for another 16.5% of the responses. Relatively few commentaries emphasized negative effects (7.1%. Converting the proportions of qualitative data into a quantitative index allowed us to analyze potential differences in emphasis according to sex, age, and school type. Though a few significant findings emerged, the larger pattern was of a uniform perceptual map across the variables for this adolescent sample. Implications drawn from this investigation highlight the need to clearly articulate concrete pathways to positive nonphysical changes (e.g., mood states, autonomy, positive character development from engagements in sports and PA.

  19. Public interest group involvement

    International Nuclear Information System (INIS)

    Shelley, P.

    1986-01-01

    Including public interest groups in the siting process for nuclear waste disposal facilities is of great importance. Controversial sitings often result in litigation, but involving public interest groups early in the process will lessen the change of this. They act as surrogates for the general public and should be considered as members of the team. It is important to remember though, that all public interest groups are different. In choosing public panels such as public advisory committees, members should not be chosen on the basis of some quota. Opposition groups should not be excluded. Also, it is important to put the right person in charge of the committee. The goal of public involvement is to identify the conflicts. This must be done during the decision process, because conflicts must be known before they can be eliminated. Regarding litigation, it is important to ease through and around legal battles. If the siting process has integrity and a good faith effort has been shown, the court should uphold the effort. In addition, it is important to be negotiable and to eliminate shortcuts

  20. 1H-NMR and HPLC studies of the changes involved in volume regulation in the muscle fibres of the crab, Hemigrapsus edwardsi.

    Science.gov (United States)

    Bedford, J J; Smith, R A; Thomas, M; Leader, J P

    1991-01-01

    1. The process of cell volume readjustment, during adaptation to salinity changes, in muscle fibres of the euryhaline New Zealand shore crab, Hemigrapsus edwardsi, involve large changes in the amounts of free amino acid. 2. These are taurine, proline, alanine, arginine, glutamic acid, glycine and serine. 3. These changes may be quantified by High Performance Liquid Chromatography, and qualitatively demonstrated by proton nuclear magnetic resonance spectroscopy.

  1. Increasing the amount of usual rehabilitation improves activity after stroke: a systematic review

    Directory of Open Access Journals (Sweden)

    Emma J Schneider

    2016-10-01

    Full Text Available Questions: In people receiving rehabilitation aimed at reducing activity limitations of the lower and/or upper limb after stroke, does adding extra rehabilitation (of the same content as the usual rehabilitation improve activity? What is the amount of extra rehabilitation that needs to be provided to achieve a beneficial effect? Design: Systematic review with meta-analysis of randomised trials. Participants: Adults aged 18 years or older that had a diagnosis of stroke. Intervention: Extra rehabilitation with the same content as usual rehabilitation aimed at reducing activity limitations of the lower and/or upper limb. Outcome measures: Activity measured as lower or upper limb ability. Results: A total of 14 studies, comprising 15 comparisons, met the inclusion criteria. Pooling data from all the included studies showed that extra rehabilitation improved activity immediately after the intervention period (SMD = 0.39, 95% CI 0.07 to 0.71, I2 = 66%. When only studies with a large increase in rehabilitation (> 100% were included, the effect was greater (SMD 0.59, 95% CI 0.23 to 0.94, I2 = 44%. There was a trend towards a positive relationship (r = 0.53, p = 0.09 between extra rehabilitation and improved activity. The turning point on the ROC curve of false versus true benefit (AUC = 0.88, p = 0.04 indicated that at least an extra 240% of rehabilitation was needed for significant likelihood that extra rehabilitation would improve activity. Conclusion: Increasing the amount of usual rehabilitation aimed at reducing activity limitations improves activity in people after stroke. The amount of extra rehabilitation that needs to be provided to achieve a beneficial effect is large. Trial registration: PROSPERO CRD42012003221. [Schneider EJ, Lannin NA, Ada L, Schmidt J (2016 Increasing the amount of usual rehabilitation improves activity after stroke: a systematic review. Journal of Physiotherapy 62: 182–187

  2. Tracing the trajectory of skill learning with a very large sample of online game players.

    Science.gov (United States)

    Stafford, Tom; Dewar, Michael

    2014-02-01

    In the present study, we analyzed data from a very large sample (N = 854,064) of players of an online game involving rapid perception, decision making, and motor responding. Use of game data allowed us to connect, for the first time, rich details of training history with measures of performance from participants engaged for a sustained amount of time in effortful practice. We showed that lawful relations exist between practice amount and subsequent performance, and between practice spacing and subsequent performance. Our methodology allowed an in situ confirmation of results long established in the experimental literature on skill acquisition. Additionally, we showed that greater initial variation in performance is linked to higher subsequent performance, a result we link to the exploration/exploitation trade-off from the computational framework of reinforcement learning. We discuss the benefits and opportunities of behavioral data sets with very large sample sizes and suggest that this approach could be particularly fecund for studies of skill acquisition.

  3. Deregulation of obesity-relevant genes is associated with progression in BMI and the amount of adipose tissue in pigs

    DEFF Research Database (Denmark)

    Mentzel, Caroline M. Junker; Cardoso, Tainã Figueiredo; Pipper, Christian Bressen

    2018-01-01

    The aim of this study was to elucidate the relative impact of three phenotypes often used to characterize obesity on perturbation of molecular pathways involved in obesity. The three obesity-related phenotypes are (1) body mass index (BMI), (2) amount of subcutaneous adipose tissue (SATa), and (3......) amount of retroperitoneal adipose tissue (RPATa). Although it is generally accepted that increasing amount of RPATa is ‘unhealthy’, a direct comparison of the relative impact of the three obesity-related phenotypes on gene expression has, to our knowledge, not been performed previously. We have used...... multiple linear models to analyze altered gene expression of selected obesity-related genes in tissues collected from 19 female pigs phenotypically characterized with respect to the obesity-related phenotypes. Gene expression was assessed by high-throughput qPCR in RNA from liver, skeletal muscle...

  4. Physical protection of small amounts of nuclear material or contaminated parts

    International Nuclear Information System (INIS)

    Zipper, R.

    2002-01-01

    In July 2001 an incident was recognized where a worker occupied with decontamination of structures in a shut down reprocessing plant for spent fuel illegally removed a small amount of radioactive material from the facility site. The investigations exhibited that he brought this material to the apartment of his partner in life and she incorporated significantly α-activity in the form of plutonium. Immediately after the incident was discovered the supervisory authorities and the operating company of the facility took action to minimize the harms to third parties arising from the radioactive material released and to prevent a similar event to occur. As the overall inventory of radioactive material in the shut down facility at the time the theft occurred was below the limit where measures of physical protection are required by the German regulatory work discussions were raised on consequences to be drawn from this incident to close this obvious gap. The German Federal Ministry for Environment, Nature Protection and Reactor Safety (BMU) as the superior competent authority therefore ordered GRS to draft a set of fundamental requirements for future rules to make a repetition of the initiating incident unlikely. Further discussions of the authorities involved on supplementary rules and guidelines aiming to better protect small amounts of radioactive material from being illegally removed out of nuclear facilities and laboratories are based on these fundamentals defined by GRS but not yet finished. (orig.)

  5. [Father involvement in childbirth].

    Science.gov (United States)

    Villalón, H; Toro, R; Riesco, I; Pinto, M; Silva, C

    2014-10-01

    Recent initiatives have promoted the participation of fathers in the early care of their children. To assess the results of a program to encourage parental involvement in childbirth. Parents of healthy term newborns were randomly allocated to participate either in the birth experience or control. The protocol included: to dry the skin, umbilical cord cutting off, weight, height, and finally give him/her to the mother for the skin-to-skin contact. Heart rate (HR), respiratory (RR) and temperature were evaluated one hour later. In the first outpatient clinic assessment, mothers completed a questionnaire. 127 fathers participated either in the birth experience or control. 62 followed the protocol and 65 the control. Both newborn groups were comparable. Also were fathers in age, education and rurality; mothers in primiparity. Significant differences: night care (37/62, 10/65 59.6% vs 15.4%, pfathers at birth, even belonging to a discouraging socio cultural environment.

  6. Deregulation of obesity-relevant genes is associated with progression in BMI and the amount of adipose tissue in pigs.

    Science.gov (United States)

    Mentzel, Caroline M Junker; Cardoso, Tainã Figueiredo; Pipper, Christian Bressen; Jacobsen, Mette Juul; Jørgensen, Claus Bøttcher; Cirera, Susanna; Fredholm, Merete

    2018-02-01

    The aim of this study was to elucidate the relative impact of three phenotypes often used to characterize obesity on perturbation of molecular pathways involved in obesity. The three obesity-related phenotypes are (1) body mass index (BMI), (2) amount of subcutaneous adipose tissue (SATa), and (3) amount of retroperitoneal adipose tissue (RPATa). Although it is generally accepted that increasing amount of RPATa is 'unhealthy', a direct comparison of the relative impact of the three obesity-related phenotypes on gene expression has, to our knowledge, not been performed previously. We have used multiple linear models to analyze altered gene expression of selected obesity-related genes in tissues collected from 19 female pigs phenotypically characterized with respect to the obesity-related phenotypes. Gene expression was assessed by high-throughput qPCR in RNA from liver, skeletal muscle and abdominal adipose tissue. The stringent statistical approach used in the study has increased the power of the analysis compared to the classical approach of analysis in divergent groups of individuals. Our approach led to the identification of key components of cellular pathways that are modulated in the three tissues in association with changes in the three obesity-relevant phenotypes (BMI, SATa and RPATa). The deregulated pathways are involved in biosynthesis and transcript regulation in adipocytes, in lipid transport, lipolysis and metabolism, and in inflammatory responses. Deregulation seemed more comprehensive in liver (23 genes) compared to abdominal adipose tissue (10 genes) and muscle (3 genes). Notably, the study supports the notion that excess amount of intra-abdominal adipose tissue is associated with a greater metabolic disease risk. Our results provide molecular support for this notion by demonstrating that increasing amount of RPATa has a higher impact on perturbation of cellular pathways influencing obesity and obesity-related metabolic traits compared to increase

  7. FTSPlot: fast time series visualization for large datasets.

    Directory of Open Access Journals (Sweden)

    Michael Riss

    Full Text Available The analysis of electrophysiological recordings often involves visual inspection of time series data to locate specific experiment epochs, mask artifacts, and verify the results of signal processing steps, such as filtering or spike detection. Long-term experiments with continuous data acquisition generate large amounts of data. Rapid browsing through these massive datasets poses a challenge to conventional data plotting software because the plotting time increases proportionately to the increase in the volume of data. This paper presents FTSPlot, which is a visualization concept for large-scale time series datasets using techniques from the field of high performance computer graphics, such as hierarchic level of detail and out-of-core data handling. In a preprocessing step, time series data, event, and interval annotations are converted into an optimized data format, which then permits fast, interactive visualization. The preprocessing step has a computational complexity of O(n x log(N; the visualization itself can be done with a complexity of O(1 and is therefore independent of the amount of data. A demonstration prototype has been implemented and benchmarks show that the technology is capable of displaying large amounts of time series data, event, and interval annotations lag-free with < 20 ms ms. The current 64-bit implementation theoretically supports datasets with up to 2(64 bytes, on the x86_64 architecture currently up to 2(48 bytes are supported, and benchmarks have been conducted with 2(40 bytes/1 TiB or 1.3 x 10(11 double precision samples. The presented software is freely available and can be included as a Qt GUI component in future software projects, providing a standard visualization method for long-term electrophysiological experiments.

  8. Cooling-water amounts, temperature, and the environment

    International Nuclear Information System (INIS)

    Koops, F.B.J.; Donze, M.; Hadderingh, R.H.

    1979-01-01

    The release of heat from power plants into a water can take place with relative small quantities of cooling water, highly warmed up accordingly, or with large quantities of cooling water slightly warmed up. The utilization of cooling water is bound to certain guidelines established by the authorities. With the intention to protect the environment, the admissable temperatures and warming-up have been strictly limited by the authorities. In the Netherlands, we have presently temporary cooling water guidelines which allow a max. temperature of the cooling water in the cooling cycle of 30 0 C and a maximum admissible temperature rise in the condenser between 7 0 C during summer and 15 0 C during winter. It has also been determined in these requirements how much cooling water at least has to be used to discharge a specified quantity of heat. Plankton, spawn and young fish are dragged with the cooling water. Harm to these organisms can be caused mechanically by pumps, sieves and the condenser or they can be harmed by the temperature rise in the condenser. Investigations showed that mechanical harm to spawn and young fish in the cooling water flow should not be ignored, and that detectable harm to plankton organisms takes place only at water temperatures above 32 0 C. The cooling water consumption can therefore be optimised as follows: The solution of a greater temperature increase and a slightly higher value for the temperature maximum can reduce the cooling water quantity. This reduction of the cooling water quantity reduces the destruction of the fish quantity, which gets into the cooling water system, especially during the summer. If the temperature rise and the temperature itself are not selected too high, the destruction of fish may be reduced without causing serious damage to the plankton. (orig.) [de

  9. Steam stable mesoporous silica MCM-41 stabilized by trace amounts of Al.

    Science.gov (United States)

    Tompkins, Jordan T; Mokaya, Robert

    2014-02-12

    Evaluation of low and ultralow Al content (Si/Al between 50 and 412) aluminosilicate Al-MCM-41 materials synthesized via three contrasting alumination routes, namely, direct mixed-gel synthesis, post-synthesis wet grafting, and post-synthesis dry grafting, indicates that trace amounts of Al introduced via dry grafting can stabilize mesoporous silica MCM-41 to steaming at 900 °C for 4 h. It was found that trace amounts of Al (Si/Al > 400) introduced via so-called dry grafting of Al stabilize the virtually purely siliceous MCM-41 to steaming, whereas Al incorporated via other methods that involve aqueous media such as direct mixed gel synthesis or wet grafting of Al offer only limited protection at low Al content. It is particularly remarkable that a post-synthesis dry grafted Al-MCM-41 material possessing trace amounts of Al (i.e., Si/Al ratio of 412) and surface area and pore volume of 1112 m(2)/g and 1.20 cm(3)/g, respectively, retains 90% (998 m(2)/g) of the surface area and 85% (1.03 cm(3)/g) of the pore volume after exposure to steaming at 900 °C for 4 h. Under similar steam treatment conditions, the mesostructure of pure silica Si-MCM-41 is virtually destroyed and undergoes a 93% reduction in surface area (958 m(2)/g to 69 m(2)/g) and 88% decrease in pore volume (0.97 cm(3)/g to 0.12 cm(3)/g). The steam stable ultralow (i.e., trace) Al containing MCM-41 materials is found to be virtually similar to mesoporous pure silica Si-MCM-41 with hardly any detectable acidity. The improvement in steam stability arises from not only the presence of trace amounts of Al, but also from an apparent increase in the level of silica condensation that is specific to dry grafted alluminosilicate MCM-41 materials. The more highly condensed framework has fewer silanol groups and therefore is more resistant to hydrolysis under steaming conditions.

  10. Derivation of total ozone amounts over Japan from NOAA/TOVS data

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, S; Taguchi, M; Okano, S; Fukunishi, H [Tohoku University, Sendai (Japan). Upper Atmosphere and Space Research Laboratory; Kawamura, H [Tohoku Univ., Sendai (Japan). Center for Atmospheric and Oceanic Studies

    1992-10-25

    A new method for the derivation of the horizontal distribution of total ozone amounts from the brightness temperature data obtained by the HIRS/2 sensor on board the NOAA satelites was developed. This method is based on the regression method considering a transmittance of the ozone layer, and also includes the second-order terms of the brightness temperatures and the transmittance of ozone layer into the regression calculation. The total ozone data obtained by TOMS were used as the true values in determinating the regression coefficients. The transmittance for the slantwise-looking condition was converted into that for the nadir-looking condition using the angle correction method. Subsequently, the angle correction was also made for the brightness temperature using the corrected transmittance. Horizontal distributions of total ozone amounts were derived by this method with around 4% of accuracy for the wide latitudinal region from 15[degree] to 60[degree], including Japan where total ozone varies largely with latitude. It was demonstrated that inclusion of the second-order terms into the regression improves the accuracy of retrieval, especially in the low-latitude regions. 15 refs., 5 figs., 1 tab.

  11. Health information search to deal with the exploding amount of health information produced.

    Science.gov (United States)

    Müller, H; Hanbury, A; Al Shorbaji, N

    2012-01-01

    This focus theme deals with the various aspects of health information search that are necessary to cope with the challenges of an increasing amount and complexity of medical information currently produced. This editorial reviews the main challenges of health information search and summarizes the five papers of this focus theme. The five papers of the focus theme cover a large part of the current challenges in health information search such as coding standards, information extraction from complex data, user requirements analysis, multimedia data analysis and the access to big data. Several future challenges are identified such as the combination of visual and textual data for information search and the difficulty to scale when analyzing big data.

  12. Forms and Amounts of Vitamin B12 in Infant Formula: A Pilot Study

    DEFF Research Database (Denmark)

    Greibe, Eva; Nexø, Ebba

    2016-01-01

    12 (cyano-B12). Here we test commercially available infant formulas. METHODS: Eleven commercially available infant formulas were measured for content of B12 and analyzed for the presence of B12-binding proteins and forms of B12 using size exclusion chromatography and HPLC. RESULTS: All infant...... formulas contained B12 by and large in accord with the informations given on the package inserts. None of the formulas contained protein-bound B12, and cyano-B12 accounted for 19-78% of the total amount of B12 present, while hydroxo-B12 constituted more or less the rest. CONCLUSIONS: This pilot study shows...... that infant formula differs from breast milk in providing the infant with free B12, rather than protein-bound B12, and by a relative high content of cyano-B12. The consequence of supplying the infant with synthetic cyano-B12 remains to be elucidated....

  13. Assembling large, complex environmental metagenomes

    Energy Technology Data Exchange (ETDEWEB)

    Howe, A. C. [Michigan State Univ., East Lansing, MI (United States). Microbiology and Molecular Genetics, Plant Soil and Microbial Sciences; Jansson, J. [USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Earth Sciences Division; Malfatti, S. A. [USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States); Tringe, S. G. [USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States); Tiedje, J. M. [Michigan State Univ., East Lansing, MI (United States). Microbiology and Molecular Genetics, Plant Soil and Microbial Sciences; Brown, C. T. [Michigan State Univ., East Lansing, MI (United States). Microbiology and Molecular Genetics, Computer Science and Engineering

    2012-12-28

    The large volumes of sequencing data required to sample complex environments deeply pose new challenges to sequence analysis approaches. De novo metagenomic assembly effectively reduces the total amount of data to be analyzed but requires significant computational resources. We apply two pre-assembly filtering approaches, digital normalization and partitioning, to make large metagenome assemblies more computationaly tractable. Using a human gut mock community dataset, we demonstrate that these methods result in assemblies nearly identical to assemblies from unprocessed data. We then assemble two large soil metagenomes from matched Iowa corn and native prairie soils. The predicted functional content and phylogenetic origin of the assembled contigs indicate significant taxonomic differences despite similar function. The assembly strategies presented are generic and can be extended to any metagenome; full source code is freely available under a BSD license.

  14. Involve women at many levels.

    Science.gov (United States)

    Huq, N

    1995-03-01

    The organizers of the 1994 International Conference on Population and Development (ICPD) realize that slowing the rate of population growth requires the involvement of women at many levels. The planning processes in countries leading up to the ICPD were required to include women, and funds became available for women to attend regional and international preparatory meetings. National delegations at the ICPD also included many more women than the previous two world population conferences in 1974 and 1984. Space was also provided at the ICPD for the involvement of nongovernmental organizations. Naripokkho, a women's advocacy organization in Bangladesh, was therefore able to communicate its message at the conference. In preparation, the organization held consultations and workshops with grassroots women in thirteen regions of Bangladesh. Approximately one third of the women in the workshops had more children than they desired, many felt that they had to have at least two sons, poor services led women to discontinue contraceptive use, and very few women reported that a lack of access to contraception or method failure was responsible for their large families. It was also determined during the preparatory phase that environmental damage cannot be linked to population in a simplistic manner, history, politics, geography, business, and economics play important roles. Once at the ICPD, Naripokkho they negotiated and lobbied the governments to influence the ICPD program of action. Gains for women were made in both language and substance. Indeed, the program of action is the most progressive population document ever issued by a mainstream institution, gives women's goals new legitimacy, and is a powerful tool for groups working at the grassroots level. Governments must now be held to their commitments made in the program.

  15. Dual Headquarters Involvement in Multibusiness Firms

    DEFF Research Database (Denmark)

    Nell, Phillip Christopher; Kappen, Philip; Dellestrand, Henrik

    The strategy literature has shown that headquarters involve themselves into subsidiary operations to add value. Yet, little is known about the extent to which multiple headquarters do so. Therefore, we investigate antecedents of corporate and divisional headquarters’ involvement in innovation...... development projects of subsidiaries. Analyses of 85 innovation development projects reveal that dual innovation importance (innovation that is important for the division and the rest of the firm), and dual dual embeddedness (innovating subsidiary is embedded both within the division and in the rest...... of the firm) lead to greater dual headquarters involvement, especially when the innovation development network is large. The results contribute to the literature on complex parenting and theory of selective headquarters involvement....

  16. [Variables determining the amount of care for very preterm neonates: the concept of medical stance].

    Science.gov (United States)

    Burguet, A; Menget, A; Chary-Tardy, A-C; Savajols, E; Abed, N; Thiriez, G

    2014-02-01

    To compare the amount of medical interventions on very preterm neonates (24-31 weeks of gestation) in two French university tertiary care centers, one of which is involved in a Neonatal Developmental Care program. A secondary objective is to assess whether this difference in medical interventions can be linked to a difference in mortality and morbidity rates. We prospectively included all very preterm neonates free from lethal malformation born live in these two centers between 2006 and 2010. These inclusion criteria were met by 1286 patients, for whom we compared the rate of five selected medical interventions: birth by caesarean section, chest intubation in the delivery room, surfactant therapy, pharmacological treatment of patent ductus arteriosus, and red blood cell transfusion. The rates of the five medical interventions were systematically lower in the center that is involved in Neonatal Developmental Care. There was no significant difference in survival at discharge with no severe cerebral ultrasound scan abnormalities between the two centers. There were, however, significantly higher rates of bronchopulmonary dysplasia and nosocomial sepsis and longer hospital stays when the patients were not involved in a Neonatal Developmental Care program. This benchmarking study shows that in France, in the first decade of the 21st century, there are as many ways to handle very preterm neonates as there are centers in which they are born. This brings to light the concept of medical stance, which is the general care approach prior to the treatment itself. This medical stance creates the overall framework for the staff's decision-making regarding neonate care. The different parameters structuring medical stance are discussed. Moreover, this study raises the problematic issue of the aftermath of benchmarking studies when the conclusion is an increase of morbidity in cases where procedure leads to more interventions. Copyright © 2013 Elsevier Masson SAS. All rights

  17. Amount of newspaper coverage of high school athletics for boys and girls on sports page and newspaper circulation.

    Science.gov (United States)

    Pedersen, Paul M; Whisenant, Warren A

    2002-02-01

    This study analyzed the amount of coverage for high school athletics in 43 newspapers with small circulation by devoting 40% of their interscholastic athletics coverage to girls in athletics, printed significantly more articles about girls' athletics than did the newspapers with medium (33%) or large (32%) circulation. Therefore, the smaller the newspaper circulation, the more equitable the coverage of athletics for girls and boys. This finding was consistent with some prior work but not all.

  18. Landspotting: Social gaming to collect vast amounts of data for satellite validation

    Science.gov (United States)

    Fritz, S.; Purgathofer, P.; Kayali, F.; Fellner, M.; Wimmer, M.; Sturn, T.; Triebnig, G.; Krause, S.; Schindler, F.; Kollegger, M.; Perger, C.; Dürauer, M.; Haberl, W.; See, L.; McCallum, I.

    2012-04-01

    At present there is no single satellite-derived global land cover product that is accurate enough to provide reliable estimates of forest or cropland area to determine, e.g., how much additional land is available to grow biofuels or to tackle problems of food security. The Landspotting Project aims to improve the quality of this land cover information by vastly increasing the amount of in-situ validation data available for calibration and validation of satellite-derived land cover. The Geo-Wiki (Geo-Wiki.org) system currently allows users to compare three satellite derived land cover products and validate them using Google Earth. However, there is presently no incentive for anyone to provide this data so the amount of validation through Geo-Wiki has been limited. However, recent competitions have proven that incentive driven campaigns can rapidly create large amounts of input. The LandSpotting Project is taking a truly innovative approach through the development of the Landspotting game. The game engages users whilst simultaneously collecting a large amount of in-situ land cover information. The development of the game is informed by the current raft of successful social gaming that is available on the internet and as mobile applications, many of which are geo-spatial in nature. Games that are integrated within a social networking site such as Facebook illustrate the power to reach and continually engage a large number of individuals. The number of active Facebook users is estimated to be greater than 400 million, where 100 million are accessing Facebook from mobile devices. The Landspotting Game has similar game mechanics as the famous strategy game "Civilization" (i.e. build, harvest, research, war, diplomacy, etc.). When a player wishes to make a settlement, they must first classify the land cover over the area they wish to settle. As the game is played on the earth surface with Google Maps, we are able to record and store this land cover/land use classification

  19. The peculiarities of large intron splicing in animals.

    Directory of Open Access Journals (Sweden)

    Samuel Shepard

    Full Text Available In mammals a considerable 92% of genes contain introns, with hundreds and hundreds of these introns reaching the incredible size of over 50,000 nucleotides. These "large introns" must be spliced out of the pre-mRNA in a timely fashion, which involves bringing together distant 5' and 3' acceptor and donor splice sites. In invertebrates, especially Drosophila, it has been shown that larger introns can be spliced efficiently through a process known as recursive splicing-a consecutive splicing from the 5'-end at a series of combined donor-acceptor splice sites called RP-sites. Using a computational analysis of the genomic sequences, we show that vertebrates lack the proper enrichment of RP-sites in their large introns, and, therefore, require some other method to aid splicing. We analyzed over 15,000 non-redundant, large introns from six mammals, 1,600 from chicken and zebrafish, and 560 non-redundant large introns from five invertebrates. Our bioinformatic investigation demonstrates that, unlike the studied invertebrates, the studied vertebrate genomes contain consistently abundant amounts of direct and complementary strand interspersed repetitive elements (mainly SINEs and LINEs that may form stems with each other in large introns. This examination showed that predicted stems are indeed abundant and stable in the large introns of mammals. We hypothesize that such stems with long loops within large introns allow intron splice sites to find each other more quickly by folding the intronic RNA upon itself at smaller intervals and, thus, reducing the distance between donor and acceptor sites.

  20. 41 CFR 301-71.307 - How do we collect the amount of a travel advance in excess of the amount of travel expenses...

    Science.gov (United States)

    2010-07-01

    ... amount of a travel advance in excess of the amount of travel expenses substantiated by the employee? 301-71.307 Section 301-71.307 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 71-AGENCY TRAVEL ACCOUNTABILITY REQUIREMENTS...

  1. Effects of the amount and schedule of varied practice after constant practice on the adaptive process of motor learning

    Directory of Open Access Journals (Sweden)

    Umberto Cesar Corrêa

    2014-12-01

    Full Text Available This study investigated the effects of different amounts and schedules of varied practice, after constant practice, on the adaptive process of motor learning. Participants were one hundred and seven children with a mean age of 11.1 ± 0.9 years. Three experiments were carried out using a complex anticipatory timing task manipulating the following components in the varied practice: visual stimulus speed (experiment 1; sequential response pattern (experiment 2; and visual stimulus speed plus sequential response pattern (experiment 3. In all experiments the design involved three amounts (18, 36, and 63 trials, and two schedules (random and blocked of varied practice. The experiments also involved two learning phases: stabilization and adaptation. The dependent variables were the absolute, variable, and constant errors related to the task goal, and the relative timing of the sequential response. Results showed that all groups worsened the performances in the adaptation phase, and no difference was observed between them. Altogether, the results of the three experiments allow the conclusion that the amounts of trials manipulated in the random and blocked practices did not promote the diversification of the skill since no adaptation was observed.

  2. Fabrication of silica ceramic membrane via sol-gel dip-coating method at different nitric acid amount

    Science.gov (United States)

    Kahlib, N. A. Z.; Daud, F. D. M.; Mel, M.; Hairin, A. L. N.; Azhar, A. Z. A.; Hassan, N. A.

    2018-01-01

    Fabrication of silica ceramics via the sol-gel method has offered more advantages over other methods in the fabrication of ceramic membrane, such as simple operation, high purity homogeneous, well defined-structure and complex shapes of end products. This work presents the fabrication of silica ceramic membrane via sol-gel dip-coating methods by varying nitric acid amount. The nitric acid plays an important role as catalyst in fabrication reaction which involved hydrolysis and condensation process. The tubular ceramic support, used as the substrate, was dipped into the sol of Tetrethylorthosilicate (TEOS), distilled water and ethanol with the addition of nitric acid. The fabricated silica membrane was then characterized by (Field Emission Scanning Electron Microscope) FESEM and (Fourier transform infrared spectroscopy) FTIR to determine structural and chemical properties at different amount of acids. From the XRD analysis, the fabricated silica ceramic membrane showed the existence of silicate hydrate in the final product. FESEM images indicated that the silica ceramic membrane has been deposited on the tubular ceramic support as a substrate and penetrate into the pore walls. The intensity peak of FTIR decreased with increasing of amount of acids. Hence, the 8 ml of acid has demonstrated the appropriate amount of catalyst in fabricating good physical and chemical characteristic of silica ceramic membrane.

  3. Identification of residues of FpvA involved in the different steps of Pvd-Fe uptake in Pseudomonas aeruginosa.

    Science.gov (United States)

    Nader, Mirella; Dobbelaere, Wim; Vincent, Michel; Journet, Laure; Adams, Hendrik; Cobessi, David; Gallay, Jacques; Schalk, Isabelle J

    2007-10-23

    FpvA is an outer membrane transporter involved in iron uptake by the siderophore pyoverdine (Pvd) in Pseudomonas aeruginosa. This transporter, like all other proteins of the same family, consists of a transmembrane 22 beta-stranded barrel occluded by a plug domain. The beta-strands of the barrel are connected by large extracellular loops and short periplasmic turns. Site-directed mutagenesis was carried out on FpvA to identify the extracellular loops or parts of these loops involved in the various stages of Pvd-Fe uptake. The G286C, W362C, and W434C mutations in loops L1, L3, and L4, respectively, disturbed the binding of the apo siderophore, as shown by time-resolved fluorescence spectroscopy. Iron uptake experiments followed by fluorescence resonance energy transfer (FRET) or using 55Fe indicated that residues W434 and G701 and, therefore, loops L4 and L9 must be involved in Pvd-Fe uptake by FpvA. The two corresponding mutants incorporated smaller than normal amounts of 55Fe into cells, and no Pvd recycling on FpvA was observed after iron release. Surprisingly, the S603C mutation in loop L7 increased the amount of Pvd-Fe transported. Our results suggest that W434 (L4), S603 (L7), and G701 (L9) are involved in the mechanism of Pvd-Fe uptake.

  4. Technological Aspects of Creating Large-size Optical Telescopes

    Directory of Open Access Journals (Sweden)

    V. V. Sychev

    2015-01-01

    Full Text Available A concept of the telescope creation, first of all, depends both on a choice of the optical scheme to form optical radiation and images with minimum losses of energy and information and on a choice of design to meet requirements for strength, stiffness, and stabilization characteristics in real telescope operation conditions. Thus, the concept of creating large-size telescopes, certainly, involves the use of adaptive optics methods and means.The level of technological capabilities to realize scientific and engineering ideas define a successful development of large-size optical telescopes in many respects. All developers pursue the same aim that is to raise an amount of information by increasing a main mirror diameter of the telescope.The article analyses the adaptive telescope designs developed in our country. Using a domestic ACT-25 telescope as an example, it considers creation of large-size optical telescopes in terms of technological aspects. It also describes the telescope creation concept features, which allow reaching marginally possible characteristics to ensure maximum amount of information.The article compares a wide range of large-size telescopes projects. It shows that a domestic project to create the adaptive ACT-25 super-telescope surpasses its foreign counterparts, and there is no sense to implement Euro50 (50m and OWL (100m projects.The considered material gives clear understanding on a role of technological aspects in development of such complicated optic-electronic complexes as a large-size optical telescope. The technological criteria of an assessment offered in the article, namely specific informational content of the telescope, its specific mass, and specific cost allow us to reveal weaknesses in the project development and define a reserve regarding further improvement of the telescope.The analysis of results and their judgment have shown that improvement of optical largesize telescopes in terms of their maximum

  5. 9 CFR 381.412 - Reference amounts customarily consumed per eating occasion.

    Science.gov (United States)

    2010-01-01

    ... Amount Ready-to-serve Reference Amount Ready-to-cook Egg mixtures, (western style omelet, souffle, egg... cook poultry cuts, including marinated, tenderized, injected cuts of poultry, poultry corn dogs...

  6. How Reservoirs Alter DOM Amount and Composition: Sources, Sinks, and Transformations

    Science.gov (United States)

    Kraus, T. E.; Bergamaschi, B. A.; Hernes, P. J.; Doctor, D. H.; Kendall, C.; Losee, R. F.; Downing, B. D.

    2011-12-01

    Reservoirs are critical components of many water supply systems as they allow the storage of water when supply exceeds demand. However, during water storage biogeochemical processes can alter both the amount and composition of dissolved organic matter (DOM), which can in turn affect water quality. While the balance between production and loss determines whether a reservoir is a net sink or source of DOM, changes in chemical composition are also relevant as they affect DOM reactivity (e.g. persistence in the environment, removability during coagulation treatment, and potential to form toxic compounds during drinking water treatment). The composition of the DOM pool also provides information about the DOM sources and processing, which can inform reservoir management. We examined the concentration and composition of DOM in San Luis Reservoir (SLR), a large off-stream impoundment of the California State Water Project. We used an array of DOM chemical tracers including dissolved organic carbon (DOC) concentration, optical properties, isotopic composition, lignin phenol content, and structural groupings determined by 13C NMR. There were periods when the reservoir was i) a net source of DOM due to the predominance of algal production (summer), ii) a net sink due to the predominance of degradation (fall/winter), and iii) balanced between production and consumption (spring). Despite only moderate variation in bulk DOC concentration (3.0-3.6 mg C/L), substantial changes in DOM composition indicated that terrestrial-derived material entering the reservoir was being degraded and replaced by aquatic-derived DOM produced within the reservoir. Results suggest reservoirs have the potential to reduce DOM amount and reactivity via degradative processes, however, these benefits can be decreased or even negated by the production of algal-derived DOM.

  7. The stable isotope amount effect: New insights from NEXRAD echo tops, Luquillo Mountains, Puerto Rico

    Science.gov (United States)

    Scholl, Martha A.; Shanley, James B.; Zegarra, Jan Paul; Coplen, Tyler B.

    2009-01-01

    The stable isotope amount effect has often been invoked to explain patterns of isotopic composition of rainfall in the tropics. This paper describes a new approach, correlating the isotopic composition of precipitation with cloud height and atmospheric temperature using NEXRAD radar echo tops, which are a measure of the maximum altitude of rainfall within the clouds. The seasonal differences in echo top altitudes and their corresponding temperatures are correlated with the isotopic composition of rainfall. These results offer another factor to consider in interpretation of the seasonal variation in isotopic composition of tropical rainfall, which has previously been linked to amount or rainout effects and not to temperature effects. Rain and cloud water isotope collectors in the Luquillo Mountains in northeastern Puerto Rico were sampled monthly for three years and precipitation was analyzed for δ18O and δ2H. Precipitation enriched in 18O and 2H occurred during the winter dry season (approximately December–May) and was associated with a weather pattern of trade wind showers and frontal systems. During the summer rainy season (approximately June–November), precipitation was depleted in 18O and 2H and originated in low pressure systems and convection associated with waves embedded in the prevailing easterly airflow. Rain substantially depleted in 18O and 2H compared to the aforementioned weather patterns occurred during large low pressure systems. Weather analysis showed that 29% of rain input to the Luquillo Mountains was trade wind orographic rainfall, and 30% of rainfall could be attributed to easterly waves and low pressure systems. Isotopic signatures associated with these major climate patterns can be used to determine their influence on streamflow and groundwater recharge and to monitor possible effects of climate change on regional water resources.

  8. Ingesting a small amount of beer reduces arterial stiffness in healthy humans.

    Science.gov (United States)

    Nishiwaki, Masato; Kora, Naoki; Matsumoto, Naoyuki

    2017-08-01

    Epidemiological studies reveal a J-shaped association between alcohol consumption and arterial stiffness, with arterial stiffening lower among mild-to-moderate drinkers than heavy drinkers or nondrinkers. This study aimed to examine the effects of ingesting a small amount of beer, corresponding to the amount consumed per day by a mild drinker, on arterial stiffness. Eleven men (20-22 years) participated, in random order and on different days, in four separate trials. The participants each drank 200 or 350 mL of alcohol-free beer (AFB200 and AFB350) or beer (B200 and B350), and were monitored for 90 min postingestion. There were no significant changes in arterial stiffness among trials that ingested AF200 or AF350. However, among trials ingesting B200 and B350, breath alcohol concentrations increased significantly, while indexes of arterial stiffness decreased significantly for approximately 60 min: carotid-femoral pulse wave velocity (B200: -0.6 ± 0.2 m/sec; B350: -0.6 ± 0.2 m/sec); brachial-ankle pulse wave velocity (B200: -53 ± 18 cm/sec; B350: -57 ± 19 cm/sec); and cardio-ankle vascular index (B200: -0.4 ± 0.1 unit; B350: -0.3 ± 0.1 unit). Furthermore, AFB showed no effect on arterial stiffness, regardless of whether or not it contained sugar, and no significant difference in antioxidant capacity was found between AFB and B. This is the first study to demonstrate that acute ingestion of relatively small amounts of beer reduces arterial stiffness (for approximately 60 min). Our data also suggest that the reduction in arterial stiffness induced by ingestion of beer is largely attributable to the effects of alcohol. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

  9. Physical feedbacks on stratus cloud amount resolve the Faint Young Sun Paradox

    Science.gov (United States)

    Goldblatt, C.; McCusker, K. E.; McDonald, V.

    2017-12-01

    Geological evidence suggests that Earth was mostly warm and not glaciated during the Archean, despite Earth receiving only around 80% of the present day amount of sunlight. 1-D models require higher abundances of greenhouse gases than geochemical proxies permit, whereas some 3-D models permit lower greenhouse gas inventories, but for reasons which are somewhat opaque. Here, we show that physically motivated changes to low cloud (stratus) amount likely played a large role in resolving the FYSP. The amount of stratus cloud is strongly linked to lower tropospheric stability [Slingo 1987; Woods and Bretherton 2006], with a stronger inversion at the planetary boundary layer trapping moisture and giving a higher stratus cloud fraction. By hypothesis, an Archean situation where the surface is heated less by sunlight and the atmosphere is heated more by absorption of thermal radiation with a stronger greenhouse, should feature a weaker inversion and less stable lower troposphere. Hence, with a weaker sun but stronger greenhouse, we expect less stratus clouds. To test this hypothesis, we run a set of carefully controlled General Circulation Model experiments using the Community Atmosphere Model. We change only the solar constant and CO2 mixing ratio, increasing CO2 and decreasing the solar constant so that the global mean surface temperature remains the same. We do not change anything else, so as to focus directly on a single hypothesis, and to keep the model as near to known conditions as possible. We find that at 80% of modern solar constant: (1) only 30,000 ppmv CO2 is required to maintain modern surface temperatures, versus the expectation of 80,000 ppmv from radiative forcing calculations. (2) The dominant change is to low cloud fraction, decreasing from 34% to 25%, with an associated reduction in short-wave cloud forcing of 20W/m/m. This can be set in the context of a 50W/m/m radiative deficit due to the weaker sun, so the cloud feedback contributes two-fifths of the

  10. Foam rheology at large deformation

    Science.gov (United States)

    Géminard, J.-C.; Pastenes, J. C.; Melo, F.

    2018-04-01

    Large deformations are prone to cause irreversible changes in materials structure, generally leading to either material hardening or softening. Aqueous foam is a metastable disordered structure of densely packed gas bubbles. We report on the mechanical response of a foam layer subjected to quasistatic periodic shear at large amplitude. We observe that, upon increasing shear, the shear stress follows a universal curve that is nearly exponential and tends to an asymptotic stress value interpreted as the critical yield stress at which the foam structure is completely remodeled. Relevant trends of the foam mechanical response to cycling are mathematically reproduced through a simple law accounting for the amount of plastic deformation upon increasing stress. This view provides a natural interpretation to stress hardening in foams, demonstrating that plastic effects are present in this material even for minute deformation.

  11. 26 CFR 1.127-1 - Amounts received under a qualified educational assistance program.

    Science.gov (United States)

    2010-04-01

    ... employee under a qualified educational assistance program described in § 1.127-2, or (2) The value of... Income § 1.127-1 Amounts received under a qualified educational assistance program. (a) Exclusion from.... (c) Amounts received under a nonqualified program. Any amount received under an educational...

  12. Effect of the amount of yeast on fermentation in mixtures of molasses and grains

    Energy Technology Data Exchange (ETDEWEB)

    Poluyanova, M T

    1960-01-01

    In the mixing of grains with molasses for ethanol fermentation, the amount of ethanol produced, the acidity, the amount of unfermented sugar, and other values change greatly with the amount of yeast cells present; for each mixture there exists not only the optimum temperature and the optimum concentration of the liquor, but there is also an optimum cell count.

  13. 17 CFR 229.912 - (Item 912) Source and amount of funds and transactional expenses.

    Science.gov (United States)

    2010-04-01

    ... sources of capital to finance such amount. (c) If all or any part of the consideration to be used by the... partnership, state the amount to be provided by each partnership and the sources of capital to finance such... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false (Item 912) Source and amount...

  14. 26 CFR 25.2701-3 - Determination of amount of gift.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Determination of amount of gift. 25.2701-3... AND GIFT TAXES GIFT TAX; GIFTS MADE AFTER DECEMBER 31, 1954 Special Valuation Rules § 25.2701-3 Determination of amount of gift. (a) Overview—(1) In general. The amount of the gift resulting from any transfer...

  15. 20 CFR 663.420 - Can the duration and amount of ITA's be limited?

    Science.gov (United States)

    2010-04-01

    ... Training Accounts § 663.420 Can the duration and amount of ITA's be limited? (a) Yes, the State or Local Board may impose limits on ITA's, such as limitations on the dollar amount and/or duration. (b) Limits... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Can the duration and amount of ITA's be...

  16. 45 CFR 160.404 - Amount of a civil money penalty.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Amount of a civil money penalty. 160.404 Section... RELATED REQUIREMENTS GENERAL ADMINISTRATIVE REQUIREMENTS Imposition of Civil Money Penalties § 160.404 Amount of a civil money penalty. (a) The amount of a civil money penalty will be determined in accordance...

  17. 20 CFR 404.212 - Computing your primary insurance amount from your average indexed monthly earnings.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Computing your primary insurance amount from... ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Computing Primary Insurance Amounts Average-Indexed-Monthly-Earnings Method of Computing Primary Insurance Amounts § 404.212 Computing your...

  18. Recent Experiments Involving Few-Nucleon Systems

    Science.gov (United States)

    Tornow, W.

    2014-08-01

    Recent experimental results are presented for reactions involving A = 3 to A = 6 nuclear systems. The emphasis is on unique data obtained at new experimental facilities. It is shown that the inertial confinement fusion facilities OMEGA and NIF provide a largely unexpected opportunity for experimental few-body physics to both obtain data of unprecedented quality and extend previous measurements to energies not accessible in the past. Whenever possible, data are compared to state-of-the-art theoretical calculations.

  19. Recent Experiments Involving Few-Nucleon Systems

    International Nuclear Information System (INIS)

    Tornow, W.

    2014-01-01

    Recent experimental results are presented for reactions involving A = 3 to A = 6 nuclear systems. The emphasis is on unique data obtained at new experimental facilities. It is shown that the inertial confinement fusion facilities OMEGA and NIF provide a largely unexpected opportunity for experimental few-body physics to both obtain data of unprecedented quality and extend previous measurements to energies not accessible in the past. Whenever possible, data are compared to state-of-the-art theoretical calculations. (author)

  20. Forest Policy Scenario Analysis: Sensitivity of Songbird Community to Changes in Forest Cover Amount and Configuration

    Directory of Open Access Journals (Sweden)

    Robert S. Rempel

    2007-06-01

    Full Text Available Changes in mature forest cover amount, composition, and configuration can be of significant consequence to wildlife populations. The response of wildlife to forest patterns is of concern to forest managers because it lies at the heart of such competing approaches to forest planning as aggregated vs. dispersed harvest block layouts. In this study, we developed a species assessment framework to evaluate the outcomes of forest management scenarios on biodiversity conservation objectives. Scenarios were assessed in the context of a broad range of forest structures and patterns that would be expected to occur under natural disturbance and succession processes. Spatial habitat models were used to predict the effects of varying degrees of mature forest cover amount, composition, and configuration on habitat occupancy for a set of 13 focal songbird species. We used a spatially explicit harvest scheduling program to model forest management options and simulate future forest conditions resulting from alternative forest management scenarios, and used a process-based fire-simulation model to simulate future forest conditions resulting from natural wildfire disturbance. Spatial pattern signatures were derived for both habitat occupancy and forest conditions, and these were placed in the context of the simulated range of natural variation. Strategic policy analyses were set in the context of current Ontario forest management policies. This included use of sequential time-restricted harvest blocks (created for Woodland caribou (Rangifer tarandus conservation and delayed harvest areas (created for American marten (Martes americana atrata conservation. This approach increased the realism of the analysis, but reduced the generality of interpretations. We found that forest management options that create linear strips of old forest deviate the most from simulated natural patterns, and had the greatest negative effects on habitat occupancy, whereas policy options

  1. Public involvement in nuclear decisions

    International Nuclear Information System (INIS)

    Ferte, J. De La

    1993-01-01

    Over the last two decades, the environment has gained an understandable degree of political prominence, drawing attention to the concept of direct participation of the public in decision-making. As part of that process, the first World Environmental Conference in Stockholm in 1972, the final act of the 1975 Helsinki Conference, the Global Nature Charter of the UN General Assembly of 1982 and the 1992 Rio conference have all increased the obligation of governments to inform their publics, and to give individuals and all categories of the public some degree of involvement in decisions that will directly affect their surroundings. The use of nuclear energy fits clearly into this process. Uncertainty in the public mind about the scientific foundation of nuclear-energy exploitation often motivates the public to intervene in the decision-making process, as does fear of catastrophic consequences. There can also be a specific reaction -crystallizing on nuclear energy - against uncontrolled technological and unlimited industrial development. In any event, there is a direct relationship between public pressure for participation and the perception of the ability - or inability - of the relevant authorities to act with a genuine sense of the wider interest. But, although the nuclear industry has often been taken as a scapegoat, the problems of public acceptance and government management that it raises are not substantially different from those in other branches of heavy industry, particularly in their social and environmental impacts. Indeed, in a large number of countries (France, Germany, the United Kingdom and the United States are examples) the mechanisms for public participation are broadly similar for both conventional industrial and nuclear installations

  2. Metamorphosed characters in dreams: constraints of conceptual structure and amount of theory of mind.

    Science.gov (United States)

    Schweickert, Richard; Xi, Zhuangzhuang

    2010-05-01

    Dream reports from 21 dreamers in which a metamorphosis of a person-like entity or animal occurred were coded for characters and animals and for inner states attributed to them (Theory of Mind). In myths and fairy tales, Kelly and Keil (1985) found that conscious beings (people, gods) tend to be transformed into entities nearby in the conceptual structure of Keil (1979). This also occurred in dream reports, but perceptual nearness seemed more important than conceptual nearness. In dream reports, most inanimate objects involved in metamorphoses with person-like entities were objects such as statues that ordinarily resemble people physically, and moreover represent people. A metamorphosis of a person-like entity or animal did not lead to an increase in the amount of Theory of Mind attribution. We propose that a character-line starts when a character enters a dream; properties and Theory of Mind attributions tend to be preserved along the line, regardless of whether, metamorphoses occur on it. Copyright © 2009 Cognitive Science Society, Inc.

  3. Polymerizations of beta-substituted allylic arsonium ylides with catalytic amounts of organoboron compounds

    International Nuclear Information System (INIS)

    Mondiere, R.

    2004-01-01

    My Ph.D. work consisted in the generalization and optimization of a new polymerization reaction involving allylic arsonium ylides and catalytic amounts of various boron compounds. Thus, various β-substituted allylic arsonium salts were produced according to synthetic strategies that depended on the nature of the functional group born by the salt. These salts were converted in situ to the corresponding arsonium ylides which were then treated with boron compounds to yield polymers. Our new method of polymerization afforded either non conjugated polyenes that are functionalized every three atoms of carbon, or statistic copolymers, depending on the nature of the group R born on the β position of the ylide. These new polymers cannot be synthesized by usual methods of polymerization. Initial molar ratios of reactants were found to give molar mass control of the synthesized polymers. This controlled polymerization allowed us to produce several bloc copolymers. All the polymers were characterized by NMR techniques, by size exclusion chromatography and, for some of them, by mass spectrometry. Investigation of their physicochemical properties will need additional experiments. (author)

  4. Dimensional stability under wet curing of mortars containing high amounts of nitrates and phosphates

    International Nuclear Information System (INIS)

    Benard, P.; Cau Dit Coumes, C.; Garrault, S.; Nonat, A.; Courtois, S.

    2008-01-01

    Investigations were carried out in order to solidify in cement some aqueous streams resulting from nuclear decommissioning processes and characterized by a high salinity (300 g/L), as well as important concentrations of nitrate (150-210 g/L) and phosphate ions (0-50 g/L). Special attention was paid to the influence of these compounds on the dimensional variations under wet curing of simulated solidified waste forms. The length changes of mortars containing nitrate salts only (KNO 3 , NaNO 3 ) were shown to be governed by a concentration effect which involved osmosis: the higher their concentration in the mixing solution, the higher the swelling. The expansion of mortars containing high amounts of phosphates (≥ 30 g/L in the mixing solution) was preceded by a shrinkage which increased with the phosphate concentration, and which could be suppressed by seeding the cement used with hydroxyapatite crystals. This transitory shrinkage was attributed to the conversion into hydroxyapatite of a precursor readily precipitated in the cement paste after mixing

  5. Access to gram scale amounts of functional globular adiponectin from E. coli inclusion bodies by alkaline-shock solubilization.

    Science.gov (United States)

    Heiker, John T; Klöting, Nora; Blüher, Matthias; Beck-Sickinger, Annette G

    2010-07-16

    The adipose tissue derived protein adiponectin exerts anti-diabetic, anti-inflammatory and anti-atherosclerotic effects. Adiponectin serum concentrations are in the microgram per milliliter range in healthy humans and inversely correlate with obesity and metabolic disorders. Accordingly, raising circulating adiponectin levels by direct administration may be an intriguing strategy in the treatment of obesity-related metabolic disorders. However production of large amounts of recombinant adiponectin protein is a primary obstacle so far. Here, we report a novel method for large amount production of globular adiponectin from E. coli inclusion bodies utilizing an alkaline-shock solubilization method without chaotropic agents followed by precipitation of the readily renaturing protein. Precipitation of the mildly solubilized protein capitalizes on advantages of inclusion body formation. This approach of inclusion body protein recovery provides access to gram scale amounts of globular adiponectin with standard laboratory equipment avoiding vast dilution or dialysis steps to neutralize the pH and renature the protein, thus saving chemicals and time. The precipitated protein is readily renaturing in buffer, is of adequate purity without a chromatography step and shows biological activity in cultured MCF7 cells and significantly lowered blood glucose levels in mice with streptozotocin induced type 1 diabetes. Copyright 2010 Elsevier Inc. All rights reserved.

  6. Heterologous expression of Pycnoporus cinnabarinus cellobiose dehydrogenase in Pichia pastoris and involvement in saccharification processes

    Directory of Open Access Journals (Sweden)

    Bey Mathieu

    2011-12-01

    Full Text Available Abstract Background Cellobiose dehydrogenase (CDH is an extracellular hemoflavoenzyme produced by lignocellulose-degrading fungi including Pycnoporus cinnabarinus. We investigated the cellulolytic system of P. cinnabarinus, focusing on the involvement of CDH in the deconstruction of lignocellulosic biomass. Results First, P. cinnabarinus growth conditions were optimized for CDH production. Following growth under cellulolytic conditions, the main components secreted were cellulases, xylanases and CDH. To investigate the contribution of P. cinnabarinus secretome in saccharification processes, the Trichoderma reesei enzymatic cocktail was supplemented with the P. cinnabarinus secretome. A significant enhancement of the degradation of wheat straw was observed with (i the production of a large amount of gluconic acid, (ii increased hemicellulose degradation, and (iii increased overall degradation of the lignocellulosic material. P. cinnabarinus CDH was heterologously expressed in Pichia pastoris to obtain large amounts of pure enzyme. In a bioreactor, the recombinant CDH (rCDH expression level reached 7800 U/L. rCDH exhibited values of biochemical parameters similar to those of the natural enzyme, and was able to bind cellulose despite the absence of a carbohydrate-binding module (CBM. Following supplementation of purified rCDH to T. reesei enzymatic cocktail, formation of gluconic acid and increased hemicellulose degradation were observed, thus confirming the previous results observed with P. cinnabarinus secretome. Conclusions We demonstrate that CDH offers an attractive tool for saccharification process enhancement due to gluconic acid production from raw lignocellulosic material.

  7. ESB application for effective synchronization of large volume measurements data

    CERN Document Server

    Wyszkowski, Przemysław Michał

    2011-01-01

    The TOTEM experiment at CERN aims at measurement of total cross section, elastic scattering and diffractive processes of colliding protons in the Large Hadron Collider. In order for the research to be possible, it is necessary to process huge amounts of data coming from variety of sources: TOTEM detectors, CMS detectors, measurement devices around the Large Hadron Collider tunnel and many other external systems. Preparing final results involves also calculating plenty of intermediate figures, which also need to be stored. In order for the work of the scientist to be effective and convenient it is crucial to provide central point for the data storage, where all raw and intermediate figures will be stored. This thesis aims at presenting the usage of Enterprise Service Bus concept in building software infrastructure for transferring large volume of measurements data. Topics discussed here include technologies and mechanisms realizing the concept of integration bus, model of data transferring system based on ...

  8. Determination of trace amounts of cerium in silicate rocks based on its candoluminescence in a calcium oxide based matrix

    International Nuclear Information System (INIS)

    Belcher, R.; Nasser, T.A.K.; Polo-Diez, L.; Townshend, A.

    1977-01-01

    A very sensitive method for the determination of cerium (above 10 ng ml -1 ) has been developed (Belcher et al., Analyst;100:415(1975)), based on the measurement of the green candoluminescence produced by cerium in a calcium oxide-calcium sulphate matrix, with sulphuric acid as a coactivator, when the matrix is inserted into a hydrogen-nitrogen-air flame. This paper describes the application of this method to the determination of trace amounts of cerium in rocks. It involves the fusion of the sample with lithium metaborate, and does not require the isolation of cerium from other components of the rock, before measuring the candoluminescence intensity of the cerium. (author)

  9. Limits to preference and the sensitivity of choice to rate and amount of food.

    Science.gov (United States)

    Aparicio, Carlos F; Baum, William M; Hughes, Christine E; Pitts, Raymond C

    2016-03-01

    Studies of choice holding food-amount ratio constant while varying food-rate ratio within sessions showed that local changes in preference depend on relative amount of food. The present study investigated whether sensitivity of choice to food-rate ratio and sensitivity to food-amount ratio are independent of one another when food-rate ratios are varied across sessions and food-amount ratios are varied within sessions. Food deliveries for rats' presses on the left and right levers were scheduled according to three different food-rate ratios of 1:1, 9:1, and 1:9; each food-rate ratio lasted for 106 sessions and was arranged independently of seven food-amount ratios (7:1, 6:2, 5:3, 4:4, 3:5, 2:6, and 1:7 food pellets) occurring within sessions in random sequence. Each amount ratio lasted for 10 food deliveries and was separated from another by a 60-s blackout. Sensitivity to rate ratio was high (1.0) across food deliveries. Sensitivity to amount ratio was low when food rates were equal across alternatives, but was high when rate ratio and amount ratio opposed one another. When rate ratio and amount ratio went in the same direction, choice ratio reached an elevenfold limit which reduced sensitivity to approximately zero. We conclude that three factors affect sensitivity to amount: (1) the limit to preference, (2) the equal effect on preference of amounts greater than four pellets, and (3) the absence of differential effects of switches in amount in the equal-rates (1:1) condition. Taken together, these findings indicate that rate and amount only sometimes combine independently as additive variables to determine preference when amount ratios vary frequently within sessions. © 2016 Society for the Experimental Analysis of Behavior.

  10. Understanding of amount and dynamics of radioactive cesium deposited on trees in Fukushima

    Energy Technology Data Exchange (ETDEWEB)

    Endo, Izuki; Ohte, Nobuhito; Iseda, Kohei; Tanoi, Keitaro; Hirose, Atsushi; Kobayashi, Natsuko I. [The University of Tokyo, 113-8657, 1-1-1 Yayoi Bunkyo-ku, Tokyo (Japan); Ishii, Nobuyoshi [National Institute of Radiological Sciences, 263-8555, 4-9-1 Anagawa, Inage-ku, Chiba-shi, Chiba (Japan); Ohashi, Mizue [University of Hyogo, 670-0092, 1-1-12 Shinzaike-Honcho, Himeji, Hyogo (Japan)

    2014-07-01

    The accident of Fukushima Daiichi nuclear power plant after the earthquake and Tsunami in March 11, 2011 caused large amount of radioactive cesium ({sup 134}Cs, {sup 137}Cs) deposition onto the forest in the surrounding areas. River water from the forest area is used for food production and also for drinking water in these regions. In order to predict how radioactive Cs diffuse and discharge from the forest catchments, it is important to understand the amount and dynamics of radioactive Cs deposited on the trees. In this report, we show our preliminary results of {sup 137}Cs deposition in forest. Study was conducted in the forest at the upstream of Kami-Oguni River catchment, northern part of Fukushima Prefecture. Three plots (2 deciduous stands and 1 Japanese cedar (Cryptomeria japonica) plantation) were set in the forest. Quercus serrata and C. japonica, a representative of deciduous and evergreen tree species in this region, were chosen from each plot. Sample trees were logged in October 2012. Stem samples were collected every 2 m from above the ground to tree top and separated into bark, sapwood and heartwood. Litter traps were set in each plot and collected every month. Leaf litter was classified among species. Also, soil samples were collected in the cylinder of 5 cm in diameter and maximum 30 cm in depth from the forest floor every month. {sup 137}Cs concentration of all samples were measured by germanium semiconductor detector or NaI(Tl) scintillation counter. Deposited {sup 137}Cs was attached strongly on the bark of Q. serrata at high concentration (9-18 kBq/kg) but there were no clear relationship with tree height. In C. japonica, {sup 137}Cs concentration was about half times lower than that of Q. serrata at 0-10 m part of the tree. {sup 137}Cs concentration in wood of C. japonica was higher than Q. serrata. {sup 137}Cs concentration of sapwood was as high as that of heartwood in C. japonica, but in Q. serrata, {sup 137}Cs concentration in sapwood was

  11. Influence of Involvement in Sports on Students' Involvement in ...

    African Journals Online (AJOL)

    This study was carried out to establish whether students' involvement in sports activities affected their involvement in academic activities. Data were collected using a self-administered questionnaire and analysed using percentages and means. Spearman's correlation coefficient was used to test the hypotheses that guided ...

  12. Effect of trace amounts of polyacrylamide (PAM) on long-term performance of activated sludge

    International Nuclear Information System (INIS)

    Luo, Yuan-ling; Yang, Zhao-hui; Xu, Zheng-yong; Zhou, Ling-jun; Zeng, Guang-ming; Huang, Jing; Xiao, Yong; Wang, Li-ke

    2011-01-01

    This study aims at evaluating the impacts of PAM addition on activated sludge performance. Four lab-scale sequencing batch reactors (SBRs), each with a working volume of 3 L, were investigated with different PAM concentrations. Experiments were conducted with varying organic loading rate and the sludge volume index (SVI), particle size, zeta potential, specific oxygen uptake rate (SOUR), mixed liquor suspended solids (MLSS), COD and ammonium removal efficiency were monitored over a 105-day period. The results showed that all of the PAM addition not only improved the removal efficiencies of COD and ammonium, but also exhibited some advantages on sludge performance. It was found that the sludge performance of settling property, flocculation and microbial activity increased with increasing concentration of PAM. However, high level of PAM (1 mg/L) led to the formation of large amounts of loose-structure flocs, which eliminated dissolved oxygen transfer and caused the sludge disintegration, resulting in bad settleability and lower microbial activity. In this way, when the dosage of PAM was 0.1 mg/L, the sludge had the best settling property and activity.

  13. Water enema CT examination of rectum cancer by reduced amount of water

    International Nuclear Information System (INIS)

    Palko, A.; Gyulai, Cs.; Fedinecz, N.; Balogh, A.; Nagy, F.

    2000-01-01

    To define whether volume of water, administered during water enema CT (WE-CT) for local staging of rectal cancer, may be reduced without compromising the diagnostic value of the examination. Materials and Methods: 29 patients with rectum cancer underwent preoperative WE-CT. Contrast-enhanced CT (equilibrium phase) measurements were performed after i.v. injection of smooth muscle relaxant and rectal administration of 400 - 500 ml lukewarm tap water. Quality of the obtained scans was evaluated and the images were analyzed for depth of tumor invasion. Results of the CT examinations were compared to findings at surgery. Results: Despite reduced dose of water enema, 19/29 examinations were of excellent quality, 6/29 good, and 4/29 poor, but still diagnostic. We achieved sensitivity (90.1), specificity (70.1) and accuracy (86.2) in differentiating tumors confined to the bowel wall from those extending beyond it. Conclusion: Large volume of water enema administered during CT examination of the rectum may cause complaints and increases the risk of complications. Our results prove that using lower amount of water does not impair the quality of examination and accuracy of local staging of rectum carcinomas. (orig.) [de

  14. Forms and Amounts of Vitamin B12 in Infant Formula: A Pilot Study.

    Directory of Open Access Journals (Sweden)

    Eva Greibe

    Full Text Available Infant formula is based on cow's milk and designed to mimic breast milk for substitution. Vitamin B12 (B12 is bound to proteins in both breast milk and cow's milk, and in milk from both species the vitamin occurs mainly in its natural form such as hydroxo-B12 with little or no synthetic B12 (cyano-B12. Here we test commercially available infant formulas.Eleven commercially available infant formulas were measured for content of B12 and analyzed for the presence of B12-binding proteins and forms of B12 using size exclusion chromatography and HPLC.All infant formulas contained B12 by and large in accord with the informations given on the package inserts. None of the formulas contained protein-bound B12, and cyano-B12 accounted for 19-78% of the total amount of B12 present, while hydroxo-B12 constituted more or less the rest.This pilot study shows that infant formula differs from breast milk in providing the infant with free B12, rather than protein-bound B12, and by a relative high content of cyano-B12. The consequence of supplying the infant with synthetic cyano-B12 remains to be elucidated.

  15. Forms and Amounts of Vitamin B12 in Infant Formula: A Pilot Study.

    Science.gov (United States)

    Greibe, Eva; Nexo, Ebba

    2016-01-01

    Infant formula is based on cow's milk and designed to mimic breast milk for substitution. Vitamin B12 (B12) is bound to proteins in both breast milk and cow's milk, and in milk from both species the vitamin occurs mainly in its natural form such as hydroxo-B12 with little or no synthetic B12 (cyano-B12). Here we test commercially available infant formulas. Eleven commercially available infant formulas were measured for content of B12 and analyzed for the presence of B12-binding proteins and forms of B12 using size exclusion chromatography and HPLC. All infant formulas contained B12 by and large in accord with the informations given on the package inserts. None of the formulas contained protein-bound B12, and cyano-B12 accounted for 19-78% of the total amount of B12 present, while hydroxo-B12 constituted more or less the rest. This pilot study shows that infant formula differs from breast milk in providing the infant with free B12, rather than protein-bound B12, and by a relative high content of cyano-B12. The consequence of supplying the infant with synthetic cyano-B12 remains to be elucidated.

  16. Effect of trace amounts of polyacrylamide (PAM) on long-term performance of activated sludge.

    Science.gov (United States)

    Luo, Yuan-ling; Yang, Zhao-hui; Xu, Zheng-yong; Zhou, Ling-jun; Zeng, Guang-ming; Huang, Jing; Xiao, Yong; Wang, Li-ke

    2011-05-15

    This study aims at evaluating the impacts of PAM addition on activated sludge performance. Four lab-scale sequencing batch reactors (SBRs), each with a working volume of 3L, were investigated with different PAM concentrations. Experiments were conducted with varying organic loading rate and the sludge volume index (SVI), particle size, zeta potential, specific oxygen uptake rate (SOUR), mixed liquor suspended solids (MLSS), COD and ammonium removal efficiency were monitored over a 105-day period. The results showed that all of the PAM addition not only improved the removal efficiencies of COD and ammonium, but also exhibited some advantages on sludge performance. It was found that the sludge performance of settling property, flocculation and microbial activity increased with increasing concentration of PAM. However, high level of PAM (1mg/L) led to the formation of large amounts of loose-structure flocs, which eliminated dissolved oxygen transfer and caused the sludge disintegration, resulting in bad settleability and lower microbial activity. In this way, when the dosage of PAM was 0.1mg/L, the sludge had the best settling property and activity. Crown Copyright © 2011. Published by Elsevier B.V. All rights reserved.

  17. Immune responses in Eimeria acervulina infected one-day-old broilers compared to amount of Eimeria in the duodenum, measured by real-time PCR

    NARCIS (Netherlands)

    Swinkels, W.J.C.; Post, J.; Cornelissen, J.B.W.J.; Engel, B.; Boerma, S.; Rebel, J.M.J.

    2006-01-01

    T-cell responses are supposed to be the major immune reactions in broilers infected with Eimeria. The nature of such T-cell responses is influenced by the species of Eimeria involved, age of the host, amount of parasites and the preceding infection history. In young chicks the intestine is still

  18. Computing in Large-Scale Dynamic Systems

    NARCIS (Netherlands)

    Pruteanu, A.S.

    2013-01-01

    Software applications developed for large-scale systems have always been difficult to de- velop due to problems caused by the large number of computing devices involved. Above a certain network size (roughly one hundred), necessary services such as code updating, topol- ogy discovery and data

  19. Instantons and Large N

    Science.gov (United States)

    Mariño, Marcos

    2015-09-01

    Preface; Part I. Instantons: 1. Instantons in quantum mechanics; 2. Unstable vacua in quantum field theory; 3. Large order behavior and Borel summability; 4. Non-perturbative aspects of Yang-Mills theories; 5. Instantons and fermions; Part II. Large N: 6. Sigma models at large N; 7. The 1=N expansion in QCD; 8. Matrix models and matrix quantum mechanics at large N; 9. Large N QCD in two dimensions; 10. Instantons at large N; Appendix A. Harmonic analysis on S3; Appendix B. Heat kernel and zeta functions; Appendix C. Effective action for large N sigma models; References; Author index; Subject index.

  20. An optimal version of an inequality involving the third symmetric ...

    Indian Academy of Sciences (India)

    It has been pointed out in [1] that means are central to the study of inequalities and have a number of applications. The large amount of work in the literature on means give them a special place in the research on inequalities. By now a number of beautiful results have been obtained. Let a ∈ Rn. ++. We then have.

  1. Maternal Involvement and Academic Achievement.

    Science.gov (United States)

    Lopez, Linda C.; Holmes, William M.

    The potential impact of several maternal involvement behaviors on teachers' ratings of children's academic skills was examined through statistical analyses. Data, based on mothers' responses to selected questions concerning maternal involvement and on teachers' ratings on the Classroom Behavior Inventory, were obtained for 115 kindergarten…

  2. Parental Involvement and Academic Achievement

    Science.gov (United States)

    Goodwin, Sarah Christine

    2015-01-01

    This research study examined the correlation between student achievement and parent's perceptions of their involvement in their child's schooling. Parent participants completed the Parent Involvement Project Parent Questionnaire. Results slightly indicated parents of students with higher level of achievement perceived less demand or invitations…

  3. Esophageal involvement in eosinophilic gastroenteritis

    Energy Technology Data Exchange (ETDEWEB)

    Matzinger, M A; Daneman, A

    1983-02-01

    The radiologic appearance of esophageal involvement due to eosinophilic gastroenteritis in a 15-year-old boy is presented. The lower two thirds of the esophagus was narrowed and the peristalsis diminished. The mucosa appeared smooth. This is the fourth reported case of esophageal involvement in eosinophilic gastroenteritis.

  4. Religion, Convention, and Paternal Involvement.

    Science.gov (United States)

    Wilcox, W. Bradford

    2002-01-01

    Examines the influence of religious affiliation and attendance on the involvement of residential fathers in one-on-one activities, dinner with their families, and youth activities and found religious effects for each of these three measures. The study indicates that religion is related to paternal involvement in all three areas that were examined.…

  5. Large Ventral Hernia

    Directory of Open Access Journals (Sweden)

    Meryl Abrams, MD

    2018-04-01

    Full Text Available History of present illness: A 46-year-old female presented to the emergency department (ED with diffuse abdominal pain and three days of poor oral intake associated with non-bilious, non-bloody vomiting. Initial vital signs consisted of a mild resting tachycardia of 111 with a temperature of 38.0 degrees Celsius (°C. On examination, the patient had a large pannus extending to the knees, which contained a hernia. She was tender in this region on examination. Laboratory values included normal serum chemistries and mild leukocytosis of 12.2. The patient reports that her abdomen had been enlarging over the previous 8 years but had not been painful until 3 days prior to presentation. The patient had no associated fever, chills, diarrhea, constipation, chest pain or shortness of breath. Significant findings: Computed tomography (CT scan with intravenous (IV contrast of the abdomen and pelvis demonstrated a large pannus containing a ventral hernia with abdominal contents extending below the knees (white circle, elongation of mesenteric vessels to accommodate abdominal contents outside of the abdomen (white arrow and air fluid levels (white arrow indicating a small bowel obstruction. Discussion: Hernias are a common chief complaint seen in the emergency department. The estimated lifetime risk of a spontaneous abdominal hernia is 5%.1 The most common type of hernia is inguinal while the next most common type of hernia is femoral, which are more common in women.1 Ventral hernias can be epigastric, incisional, or primary abdominal. An asymptomatic, reducible hernia can be followed up as outpatient with a general surgeon for elective repair.2 Hernias become problematic when they are either incarcerated or strangulated. A hernia is incarcerated when the hernia is irreducible and strangulated when its blood supply is compromised. A complicated hernia, especially strangulated, can have a mortality of greater than 50%.1 It is key to perform a thorough history

  6. Fast crawling methods of exploring content distributed over large graphs

    KAUST Repository

    Wang, Pinghui; Zhao, Junzhou; Lui, John C. S.; Towsley, Don; Guan, Xiaohong

    2018-01-01

    Despite recent effort to estimate topology characteristics of large graphs (e.g., online social networks and peer-to-peer networks), little attention has been given to develop a formal crawling methodology to characterize the vast amount of content

  7. Ego involvement increases doping likelihood.

    Science.gov (United States)

    Ring, Christopher; Kavussanu, Maria

    2018-08-01

    Achievement goal theory provides a framework to help understand how individuals behave in achievement contexts, such as sport. Evidence concerning the role of motivation in the decision to use banned performance enhancing substances (i.e., doping) is equivocal on this issue. The extant literature shows that dispositional goal orientation has been weakly and inconsistently associated with doping intention and use. It is possible that goal involvement, which describes the situational motivational state, is a stronger determinant of doping intention. Accordingly, the current study used an experimental design to examine the effects of goal involvement, manipulated using direct instructions and reflective writing, on doping likelihood in hypothetical situations in college athletes. The ego-involving goal increased doping likelihood compared to no goal and a task-involving goal. The present findings provide the first evidence that ego involvement can sway the decision to use doping to improve athletic performance.

  8. Amounts of artificial food dyes and added sugars in foods and sweets commonly consumed by children.

    Science.gov (United States)

    Stevens, Laura J; Burgess, John R; Stochelski, Mateusz A; Kuczek, Thomas

    2015-04-01

    Artificial food colors (AFCs) are used to color many beverages, foods, and sweets in the United States and throughout the world. In the United States, the Food and Drug Administration (FDA) limits the AFCs allowed in the diet to 9 different colors. The FDA certifies each batch of manufactured AFCs to guarantee purity and safety. The amount certified has risen from 12 mg/capita/d in 1950 to 62 mg/capita/d in 2010. Previously, we reported the amounts of AFCs in commonly consumed beverages. In this article, the amounts of AFCs in commonly consumed foods and sweets are reported. In addition, the amount of sugars in each product is included. Amounts of AFCs reported here along with the beverage data show that many children could be consuming far more dyes than previously thought. Clinical guidance is given to help caregivers avoid AFCs and reduce the amount of sugars in children's diets. © The Author(s) 2014.

  9. Diagnostic value of determination of amount of urinary excretion of proteins for early diabetic nephropathy

    International Nuclear Information System (INIS)

    Li Zhuocheng; Chen Jianxiong; Yan Dewen

    2007-01-01

    Objective: To investigate the value of detection of changes of the amount of usinary excretion of albumin, β 2 -m, Tamm- Horsfall protein and α 1 -m for diagnosis of early diabetic nephropathy. Methods: The amounts of 24h urinary excretion of albumin, β 2 -m, Tamm-Horsfall protein and α 1 -m were determined with RIA in 78 patients with diabetes mellitus and 40 controls. Results: The amounts of 24h urinary excretion of albumin, β 2 -m, α 1 -m in patients with diabetes mellitus were significantly higher than those in controls (P<0.01 ), while the amount of Tamm-Horsfall protein was significantly lower (P<0.01). Among the diabetic patients, the changes of the amount of protein excretion were more pronounced in those with advanced impairment of renal function. Conclusion: Determination of amount of urinary excretion of proteins was helpful for diagnosis and assessment of early diabetic nephropathy. (authors)

  10. Apparatus and method of measuring fluctuations of excavated mud amount in a slurry line

    International Nuclear Information System (INIS)

    Yamazaki, H.; Kubota, R.; Uchida, Y.; Kasuya, T.; Seki, N.

    1976-01-01

    An apparatus and method for measuring fluctuations in amount of soil in slurry or soil-containing fluid line is described. Each system of feeding the slurry typically to tunneling face and draining it therefrom in the slurry line is provided with gamma-ray densimeter and electromagnetic flow-meter to obtain respective amounts of soil only (dry-soil amounts) in the slurry flowing through each of said systems from respective outputs of these meters in each system, so that actually excavated amount through ground layer of a shielded excavator at the tunneling face can be measured by the difference between the respective dry-soil amounts. The excavator will be advanced depending on this measured amount

  11. The perturbation theory in the fundamental mode. Its application to the analysis of neutronic experiments involving small amounts of materials in fast neutron multiplying media

    International Nuclear Information System (INIS)

    Remsak, Stanislav.

    1975-01-01

    The formalism of the perturbation theory at the first order, is developed in its simplest form: diffusion theory in the fundamental mode and then the more complex formalism of the transport theory in the fundamental mode. A comparison shows the effect of the angular correlation between the fine structures of the flux and its adjoint function, the difference in the treatment of neutron leakage phenomena, and the existence of new terms in the perturbation formula, entailing a reactivity representation in the diffusion theory that is not quite exact. Problems of using the formalism developed are considered: application of the multigroup formalism, transients of the flux and its adjoint function, validity of the first order approximation etc. A detailed analysis allows the formulation of a criterion specifying the validity range. Transients occuring in the reference medium are also treated. A set of numerical tests for determining a method of elimination of transient effects is presented. Some differential experiments are then discussed: sodium blowdown in enriched uranium or plutonium cores, experiments utilizing some structural materials (iron and oxygen) and plutonium sample oscillations. The Cadarache version II program was systematically used but the analysis of the experiments of plutonium sample oscillation in Ermine required the Cadarache version III program [fr

  12. The Amateurs' Love Affair with Large Datasets

    Science.gov (United States)

    Price, Aaron; Jacoby, S. H.; Henden, A.

    2006-12-01

    Amateur astronomers are professionals in other areas. They bring expertise from such varied and technical careers as computer science, mathematics, engineering, and marketing. These skills, coupled with an enthusiasm for astronomy, can be used to help manage the large data sets coming online in the next decade. We will show specific examples where teams of amateurs have been involved in mining large, online data sets and have authored and published their own papers in peer-reviewed astronomical journals. Using the proposed LSST database as an example, we will outline a framework for involving amateurs in data analysis and education with large astronomical surveys.

  13. On-line monitoring of water amount in fresh concrete by radioactive-wave method

    International Nuclear Information System (INIS)

    Kemi, T.; Arai, M.; Enomoto, S.; Suzki, K.; Kumahara, Y.

    2003-01-01

    The committee on nondestructive inspection for steel reinforced concrete structures in the Federation of Construction Materials Industries, Japan has published a proposed standard for on-line monitoring of water amount in fresh concrete by the radioactive wave method. By applying a neutron technique, water amount in fresh concrete is estimated continuously from the energy consumption of neutron due to hydrogen. A standard is discussed along with results of verification tests. Thus, on-line monitoring for water amount is proposed

  14. Amount of work : studies on premature death and subjective health in a work life balance perspective

    OpenAIRE

    Nylén, Charlotta

    2006-01-01

    The aim of this thesis is to increase knowledge about the association between amount of work and health. Amount of work is measured as unemployment, excessive work, and interference between work and home. Two studies, based on the Swedish Twin Register, consider amount of work in work-related settings and focus on mortality in both sexes (n=20 632). Two studies take into account demands from both professional and domestic settings and consider their impact on subjective heal...

  15. A sorites paradox in the conventional definition of amount of substance

    OpenAIRE

    Nigel Wheatley

    2011-01-01

    The conventional definition of amount of substance _n_ is as a quantity proportional to number of entities _N_. This implies that n is discrete for small _N_ while _n_ is considered to be continuous at the macroscopic scale, leading to a sorites paradox. A practical criterion is proposed for distinguishing between amount of substance and number of entities, and the implications for the conventional definition of amount of substance are discussed.

  16. 40 CFR 1065.645 - Amount of water in an ideal gas.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Amount of water in an ideal gas. 1065... in an ideal gas. This section describes how to determine the amount of water in an ideal gas, which... of water in an ideal gas, x H20, as follows: ER30AP10.034 Where: x H20 = amount of water in an ideal...

  17. Nuclear waste in a repository: amount as a factor in risk duration

    International Nuclear Information System (INIS)

    Zen, E.

    1980-01-01

    The relationship between the amount of nuclear waste in a nuclear repository and the safety of the repository is examined. It is shown that the amount of a given hazardous nuclide that is potentially leachable depends on the initial amount of waste in the repository and the time that has elapsed since the repository was put into operation. Nuclear repository safety can be enhanced if repositories are designed as modular units with leach-resistant watertight compartments

  18. Evaluation of Amount of Blood in Dry Blood Spots: Ring-Disk Electrode Conductometry.

    Science.gov (United States)

    Kadjo, Akinde F; Stamos, Brian N; Shelor, C Phillip; Berg, Jordan M; Blount, Benjamin C; Dasgupta, Purnendu K

    2016-06-21

    A fixed area punch in dried blood spot (DBS) analysis is assumed to contain a fixed amount of blood, but the amount actually depends on a number of factors. The presently preferred approach is to normalize the measurement with respect to the sodium level, measured by atomic spectrometry. Instead of sodium levels, we propose electrical conductivity of the extract as an equivalent nondestructive measure. A dip-type small diameter ring-disk electrode (RDE) is ideal for very small volumes. However, the conductance (G) measured by an RDE depends on the depth (D) of the liquid below the probe. There is no established way of computing the specific conductance (σ) of the solution from G. Using a COMSOL Multiphysics model, we were able to obtain excellent agreement between the measured and the model predicted conductance as a function of D. Using simulations over a large range of dimensions, we provide a spreadsheet-based calculator where the RDE dimensions are the input parameters and the procedure determines the 99% of the infinite depth conductance (G99) and the depth D99 at which this is reached. For typical small diameter probes (outer electrode diameter ∼ <2 mm), D99 is small enough for dip-type measurements in extract volumes of ∼100 μL. We demonstrate the use of such probes with DBS extracts. In a small group of 12 volunteers (age 20-66), the specific conductance of 100 μL aqueous extracts of 2 μL of spotted blood showed a variance of 17.9%. For a given subject, methanol extracts of DBS spots nominally containing 8 and 4 μL of blood differed by a factor of 1.8-1.9 in the chromatographically determined values of sulfate and chloride (a minor and major constituent, respectively). The values normalized with respect to the conductance of the extracts differed by ∼1%. For serum associated analytes, normalization of the analyte value by the extract conductance can thus greatly reduce errors from variations in the spotted blood volume/unit area.

  19. A simple and fast determination of microgram thorium in organic solution containing several hundreds times amount of uranium

    International Nuclear Information System (INIS)

    Yin Duanzhi; Cao Benhong; Yang Jinfeng

    1991-01-01

    Using spectrophotometric method, microgram thorium in 30% TBP-kerosene system containing large amount of uranium was successfully determined after one-step back-extraction with hydrochloric acid. The recovery of thorium is more than 98%, and the separation factor α U/Th is over 1 x 10 3 . Being reliable, simple and fast, the recommended method has been used in the research on spent fuel reprocessing and is expected applicable to other neutral phosphate extraction systems such as TOPO and DMHMP

  20. Energy Inputs Uncertainty: Total Amount, Distribution and Correlation Between Different Forms of Energy

    Science.gov (United States)

    Deng, Yue

    2014-01-01

    Describes solar energy inputs contributing to ionospheric and thermospheric weather processes, including total energy amounts, distributions and the correlation between particle precipitation and Poynting flux.

  1. Large Neighborhood Search

    DEFF Research Database (Denmark)

    Pisinger, David; Røpke, Stefan

    2010-01-01

    Heuristics based on large neighborhood search have recently shown outstanding results in solving various transportation and scheduling problems. Large neighborhood search methods explore a complex neighborhood by use of heuristics. Using large neighborhoods makes it possible to find better...... candidate solutions in each iteration and hence traverse a more promising search path. Starting from the large neighborhood search method,we give an overview of very large scale neighborhood search methods and discuss recent variants and extensions like variable depth search and adaptive large neighborhood...

  2. Exposure amount and timing of solar irradiation during pregnancy and the risk of sensitization in children.

    Science.gov (United States)

    Koh, Hyun Yong; Cho, Eunhae; Lee, So-Yeon; Kim, Woo Kyung; Park, Yong Mean; Kim, Jihyun; Ahn, Kangmo; Lee, Seung Won; Kim, Mi Ae; Hahm, Myung-Il; Chae, Yoomi; Lee, Kee-Jae; Kwon, Ho-Jang; Han, Man Yong

    2018-04-01

    Solar irradiation affects sensitization to aeroallergens and the prevalence of allergic diseases. Little is known, however, about how the time and amount of solar irradiation during pregnancy affects such risks in children. We aimed to find out how solar irradiation during pregnancy affects sensitization to aero-allergens and the prevalence of allergic diseases in children. This population-based cross-sectional study involved 7301 aged 6 years and aged 12 years children. Maternal exposure to solar irradiation during pregnancy was evaluated using data from weather stations closest to each child's birthplace. Monthly average solar irradiation during the second and third trimesters was calculated with rank by quartiles. Risks of allergic sensitization and allergic disease were estimated. Relative to the first (lowest) quartile, the adjusted odds ratio (aOR) for allergic sensitization in the fourth (highest) quartile was lowest within solar irradiation during pregnancy months 5-6 (aOR = 0.823, 95% CI 0.720-0.942, p solar irradiation (aOR = 1.167, 95% CI 1.022-1.333, p solar irradiation was analyzed as a continuous variable during months 5 (aOR = 0.975, 95% CI 0.962-0.989, p solar irradiation during months 7-8 increased the risk of asthma (aOR = 1.309, 95% CI 1.024-1.674, p = 0.032). Maternal exposure to solar irradiation during the second trimester of pregnancy associated with reduced aeroallergen sensitization, whereas solar irradiation during the third trimester was related to increased sensitization to aeroallergens. Copyright © 2017 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.

  3. Very low amounts of glucose cause repression of the stress-responsive gene HSP12 in Saccharomyces cerevisiae.

    Science.gov (United States)

    de Groot, E; Bebelman, J P; Mager, W H; Planta, R J

    2000-02-01

    Changing the growth mode of Saccharomyces cerevisiae by adding fermentable amounts of glucose to cells growing on a non-fermentable carbon source leads to rapid repression of general stress-responsive genes like HSP12. Remarkably, glucose repression of HSP12 appeared to occur even at very low glucose concentrations, down to 0.005%. Although these low levels of glucose do not induce fermentative growth, they do act as a growth signal, since upon addition of glucose to a concentration of 0.02%, growth rate increased and ribosomal protein gene transcription was up-regulated. In an attempt to elucidate how this type of glucose signalling may operate, several signalling mutants were examined. Consistent with the low amounts of glucose that elicit HSP12 repression, neither the main glucose-repression pathway nor cAMP-dependent activation of protein kinase A appeared to play a role in this regulation. Using mutants involved in glucose metabolism, evidence was obtained suggesting that glucose 6-phosphate serves as a signalling molecule. To identify the target for glucose repression on the promoter of the HSP12 gene, a promoter deletion series was used. The major transcription factors governing (stress-induced) transcriptional activation of HSP12 are Msn2p and Msn4p, binding to the general stress-responsive promoter elements (STREs). Surprisingly, glucose repression of HSP12 appeared to be independent of Msn2/4p: HSP12 transcription in glycerol-grown cells was unaffected in a deltamsn2deltamsn4 strain. Nevertheless, evidence was obtained that STRE-mediated transcription is the target of repression by low amounts of glucose. These data suggest that an as yet unidentified factor is involved in STRE-mediated transcriptional regulation of HSP12.

  4. GOVERNMENT INVOLVEMENT IN CONSUMPTION BEHAVIOUR

    Directory of Open Access Journals (Sweden)

    CRISTINA ZAMFIR

    2010-01-01

    Full Text Available In this article, we will follow the involvement that the government has,through its expenses, on the consumption behavior. The involvement that the government has inthe consumption behavior is made through fees and taxes that are applied on income. Fees andtaxes are applied to the different forms of income but in this article we will be focused only onthe influence of them on wages. In order to analyze the involvement of government expenses onconsumption behavior an utility model will be used.

  5. From phenotypic to molecular polymorphisms involved in naturally occurring variation for plant development

    NARCIS (Netherlands)

    Alonso-Blanco, C.; Mendez-Vigo, B.; Koornneef, M.

    2005-01-01

    An enormous amount of naturally occurring genetic variation affecting development is found within wild and domesticated plant species. This diversity is presumably involved in plant adaptation to different natural environments or in human preferences. In addition, such intraspecific variation

  6. Large scale electrolysers

    International Nuclear Information System (INIS)

    B Bello; M Junker

    2006-01-01

    Hydrogen production by water electrolysis represents nearly 4 % of the world hydrogen production. Future development of hydrogen vehicles will require large quantities of hydrogen. Installation of large scale hydrogen production plants will be needed. In this context, development of low cost large scale electrolysers that could use 'clean power' seems necessary. ALPHEA HYDROGEN, an European network and center of expertise on hydrogen and fuel cells, has performed for its members a study in 2005 to evaluate the potential of large scale electrolysers to produce hydrogen in the future. The different electrolysis technologies were compared. Then, a state of art of the electrolysis modules currently available was made. A review of the large scale electrolysis plants that have been installed in the world was also realized. The main projects related to large scale electrolysis were also listed. Economy of large scale electrolysers has been discussed. The influence of energy prices on the hydrogen production cost by large scale electrolysis was evaluated. (authors)

  7. Large Pelagics Intercept Survey

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Large Pelagics Intercept Survey (LPIS) is a dockside survey of private and charterboat captains who have just completed fishing trips directed at large pelagic...

  8. Improving the Phosphoproteome Coverage for Limited Sample Amounts Using TiOsub>2sub>-SIMAC-HILIC (TiSH) Phosphopeptide Enrichment and Fractionation

    DEFF Research Database (Denmark)

    Engholm-Keller, Kasper; Larsen, Martin R

    2016-01-01

    spectrometry (LC-MS/MS) analysis. Due to the sample loss resulting from fractionation, this procedure is mainly performed when large quantities of sample are available. To make large-scale phosphoproteomics applicable to smaller amounts of protein we have recently combined highly specific TiO2-based...... protocol we describe the procedure step by step to allow for comprehensive coverage of the phosphoproteome utilizing only a few hundred micrograms of protein....

  9. Large electrostatic accelerators

    International Nuclear Information System (INIS)

    Jones, C.M.

    1984-01-01

    The paper is divided into four parts: a discussion of the motivation for the construction of large electrostatic accelerators, a description and discussion of several large electrostatic accelerators which have been recently completed or are under construction, a description of several recent innovations which may be expected to improve the performance of large electrostatic accelerators in the future, and a description of an innovative new large electrostatic accelerator whose construction is scheduled to begin next year

  10. Public involvement in the dose reconstruction study: the colorado story

    International Nuclear Information System (INIS)

    Morin, Norma C.; Lockhart, Ann J.

    2000-01-01

    soil near the plant to measure the amount of plutonium and other radioactive materials present. Some sediment samples from nearby Standley Lake also were analyzed. This unique process educated and involved participants in a meaningful way. The measured plutonium concentrations, were largely consistent with the concentrations and distribution of radioactive materials found by other soil studies of the area. These public involvement activities made more citizens in communities near the plant aware of the research and also educated them about the complex processes and issues involved in reconstructing historical releases from a nuclear weapons plant. When the findings of the project were announced in August 1999, the most critical concerned citizens had a good understanding of how the work was done and what the results meant. The study team heard little public opposition for the research results at the end of the project. A proactive public involvement program allowed the team to address issues as they arose, rather than at the end of the study. (author)

  11. Involvement of hyaluronidases in colorectal cancer

    International Nuclear Information System (INIS)

    Bouga, Helen; Tsouros, Isidoros; Bounias, Dimitrios; Kyriakopoulou, Dora; Stavropoulos, Michael S; Papageorgakopoulou, Nikoletta; Theocharis, Dimitrios A; Vynios, Demitrios H

    2010-01-01

    Hyaluronidases belong to a class of enzymes that degrade, predominantly, hyaluronan. These enzymes are known to be involved in physiological and pathological processes, such as tumor growth, infiltration and angiogenesis, but their exact role in tumor promotion or suppression is not clear yet. Advanced colorectal cancer is associated with elevated amounts of hyaluronan of varying size. The aim of the present study was therefore to illuminate the importance of hyaluronidases in colon carcinoma progression. The patients' samples (macroscopically normal and cancerous) were subjected to sequential extraction with PBS, 4 M GdnHCl and 4 M GdnHCl - 1% Triton X-100. The presence of the various hyaluronidases in the extracts was examined by zymography and western blotting. Their expression was also examined by RT-PCR. Among hyaluronidases examined, Hyal-1, -2, -3 and PH-20 were detected. Their activity was higher in cancerous samples. Hyal-1 and Hyal-2 were overexpressed in cancerous samples, especially in advanced stages of cancer. Both isoforms were mainly extracted with PBS. Hyal-3 was observed only in the third extract of advanced stages of cancer. PH-20 was abundant in all three extracts of all stages of cancer. The expression of only Hyal-1 and PH-20 was verified by RT-PCR. A high association of hyaluronidases in colorectal cancer was observed. Each hyaluronidase presented different tissue distribution, which indicated the implication of certain isoforms in certain cancer stages. The results provided new evidence on the mechanisms involved in the progression of colorectal cancer

  12. Black parental involvement in education

    African Journals Online (AJOL)

    Erna Kinsey

    The South African Schools Act of 1996 (SASA) provides formal power in education to parents as well as communities. ... Review of selected studies on parental involvement in ..... Anna, a Grade 11 teacher, summed up the feelings of the.

  13. Organizational Commitment and Nurses' Characteristics as Predictors of Job Involvement.

    Science.gov (United States)

    Alammar, Kamila; Alamrani, Mashael; Alqahtani, Sara; Ahmad, Muayyad

    2016-01-01

    To predict nurses' job involvement on the basis of their organizational commitment and personal characteristics at a large tertiary hospital in Saudi Arabia. Data were collected in 2015 from a convenience sample of 558 nurses working at a large tertiary hospital in Riyadh, Saudi Arabia. A cross-sectional correlational design was used in this study. Data were collected using a structured questionnaire. All commitment scales had significant relationships. Multiple linear regression analysis revealed that the model predicted a sizeable proportion of variance in nurses' job involvement (p organizational commitment enhances job involvement, which may lead to more organizational stability and effectiveness.

  14. 5 CFR 870.705 - Amount and election of Option B and Option C.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Amount and election of Option B and Option C. 870.705 Section 870.705 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED... Compensationers § 870.705 Amount and election of Option B and Option C. (a) The number of multiples of Option B...

  15. 26 CFR 5.1502-45 - Limitation on losses to amount at risk.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Limitation on losses to amount at risk. 5.1502... Limitation on losses to amount at risk. (a) In general—(1) Scope. This section applies to a loss of any subsidiary if the common parent's stock meets the stock ownership requirement described in section 465(a)(1...

  16. 24 CFR 982.635 - Homeownership option: Amount and distribution of monthly homeownership assistance payment.

    Science.gov (United States)

    2010-04-01

    ... CHOICE VOUCHER PROGRAM Special Housing Types Homeownership Option § 982.635 Homeownership option: Amount and distribution of monthly homeownership assistance payment. (a) Amount of monthly homeownership... distribution of monthly homeownership assistance payment. 982.635 Section 982.635 Housing and Urban Development...

  17. 20 CFR 416.415 - Amount of benefits; eligible individual is disabled child under age 18.

    Science.gov (United States)

    2010-04-01

    ... and your benefit rate will be $30 a month. (b) If you are a disabled child under age 18 and do not... payable if you received benefits as a child under § 416.1165(i), your benefit will be the amount payable... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Amount of benefits; eligible individual is...

  18. 34 CFR 34.20 - Amount to be withheld under multiple garnishment orders.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Amount to be withheld under multiple garnishment orders. 34.20 Section 34.20 Education Office of the Secretary, Department of Education ADMINISTRATIVE WAGE... other Federal law requires a different priority, the employer must pay us the amount calculated under...

  19. 26 CFR 1.1441-3 - Determination of amounts to be withheld.

    Science.gov (United States)

    2010-04-01

    ...: Example. (i) Facts. Corporation X, a publicly traded corporation with both U.S. and foreign shareholders... paragraph (f) of this section apply. (2) Payments in foreign currency. If the amount subject to withholding tax is paid in a currency other than the U.S. dollar, the amount of withholding under section 1441...

  20. 34 CFR 75.232 - The cost analysis; basis for grant amount.

    Science.gov (United States)

    2010-07-01

    ... Secretary sets the amount of a new grant, the Secretary does a cost analysis of the project. The Secretary... objectives of the project with reasonable efficiency and economy under the budget in the application... 34 Education 1 2010-07-01 2010-07-01 false The cost analysis; basis for grant amount. 75.232...

  1. 29 CFR 1620.6 - Coverage is not based on amount of covered activity.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Coverage is not based on amount of covered activity. 1620.6 Section 1620.6 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION THE EQUAL PAY ACT § 1620.6 Coverage is not based on amount of covered activity. The FLSA makes no...

  2. 13 CFR 107.1160 - Maximum amount of Leverage for a Section 301(d) Licensee.

    Science.gov (United States)

    2010-01-01

    ... Leverage, you must maintain Venture Capital Financings (at cost) that equal at least 30 percent of your... maintain at least the same dollar amount of Venture Capital Financings (at cost). (e) Definition of “Total... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Maximum amount of Leverage for a...

  3. 10 CFR 1015.505 - Minimum amount of referrals to the Department of Justice.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Minimum amount of referrals to the Department of Justice... THE UNITED STATES Referrals to the Department of Justice § 1015.505 Minimum amount of referrals to the Department of Justice. (a) DOE shall not refer for litigation claims of less than $2,500, exclusive of...

  4. 24 CFR 511.75 - Disbursement of rental rehabilitation grant amounts: Cash and Management Information System.

    Science.gov (United States)

    2010-04-01

    ... rehabilitation grant amounts: Cash and Management Information System. 511.75 Section 511.75 Housing and Urban... rehabilitation grant amounts: Cash and Management Information System. (a) General. Rental Rehabilitation grants.... Any drawdown is conditioned upon the submission of satisfactory information by the grantee or State...

  5. 29 CFR 4206.7 - Amount of credit in plans using the direct attribution method.

    Science.gov (United States)

    2010-07-01

    ... TO A PARTIAL WITHDRAWAL § 4206.7 Amount of credit in plans using the direct attribution method. In a plan that uses the direct attribution allocation method described in section 4211(c)(4) of ERISA, the... 29 Labor 9 2010-07-01 2010-07-01 false Amount of credit in plans using the direct attribution...

  6. 6 CFR 13.31 - Determining the amount of penalties and assessments.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Determining the amount of penalties and assessments. 13.31 Section 13.31 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.31 Determining the amount of penalties and assessments. (a) In...

  7. 33 CFR 25.117 - Proof of amount claimed for personal injury or death.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Proof of amount claimed for personal injury or death. 25.117 Section 25.117 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL CLAIMS General § 25.117 Proof of amount claimed for personal injury or death. The following evidence must be presented...

  8. 42 CFR 3.404 - Amount of a civil money penalty.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Amount of a civil money penalty. 3.404 Section 3... money penalty. (a) The amount of a civil money penalty will be determined in accordance with paragraph (b) of this section and § 3.408 of this subpart. (b) The Secretary may impose a civil money penalty...

  9. 42 CFR 488.436 - Civil money penalties: Waiver of hearing, reduction of penalty amount.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Civil money penalties: Waiver of hearing, reduction... Civil money penalties: Waiver of hearing, reduction of penalty amount. (a) Waiver of a hearing. The... the civil money penalty. (b) Reduction of penalty amount. (1) If the facility waives its right to a...

  10. 42 CFR 405.740 - Principles for determining the amount in controversy.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Principles for determining the amount in... Reconsiderations and Appeals Under Medicare Part A § 405.740 Principles for determining the amount in controversy... more appellants, the Secretary may assert that the aggregation principles contained in this subpart may...

  11. 42 CFR 405.817 - Principles for determining amount in controversy.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Principles for determining amount in controversy... the Medicare Part B Program § 405.817 Principles for determining amount in controversy. (a) Individual... may assert that the aggregation principles contained in this subpart may be applied to determine the...

  12. 26 CFR 1.642(c)-1 - Unlimited deduction for amounts paid for a charitable purpose.

    Science.gov (United States)

    2010-04-01

    ... the election was made, (iii) The office of the district director, or the service center, where the....642(c)-1 Unlimited deduction for amounts paid for a charitable purpose. (a) In general. (1) Any part... election, to a related estate, as defined under § 1.645-1(b), for the amount so paid. (2) In determining...

  13. 5 CFR 838.1111 - Amounts subject to child abuse judgment enforcement orders.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Amounts subject to child abuse judgment... Under the Child Abuse Accountability Act Availability of Funds § 838.1111 Amounts subject to child abuse... child abuse enforcement orders only if all of the conditions necessary for payment of the employee...

  14. Work-Family Conflict: Does Educational Attainment Influence the Amount of Negative Spillover?

    Science.gov (United States)

    Erarslan, Ayse Burcin

    2009-01-01

    Using a data from a purposive sample of 216 women and 218 men in Turkey, the relationship between educational attainment and the amount of negative spillover from job-to-home and home-to-job was examined. It was hypothesized that men and women with higher levels of education have less amount of negative spillover in both directions. Certain work…

  15. 26 CFR 1.179-2 - Limitations on amount subject to section 179 election.

    Science.gov (United States)

    2010-04-01

    ... trade or business and interest from working capital of the trade or business. Taxable income derived... aggregate amount of partnership items, deductions and losses are treated as negative income. Any limitation... aggregate amount of S corporation items, deductions and losses are treated as negative income. Any...

  16. 24 CFR 203.260 - Amount of mortgage insurance premium (periodic MIP).

    Science.gov (United States)

    2010-04-01

    ... Mortgage Insurance Premiums-Periodic Payment § 203.260 Amount of mortgage insurance premium (periodic MIP... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Amount of mortgage insurance premium (periodic MIP). 203.260 Section 203.260 Housing and Urban Development Regulations Relating to...

  17. Dynamics of Choice: Relative Rate and Amount Affect Local Preference at Three Different Time Scales

    Science.gov (United States)

    Aparicio, Carlos F.; Baum, William M.

    2009-01-01

    To examine extended control over local choice, the present study investigated preference in transition as food-rate ratio provided by two levers changed across seven components within daily sessions, and food-amount ratio changed across phases. Phase 1 arranged a food-amount ratio of 4:1 (i.e., the left lever delivered four pellets and the right…

  18. Large truck and bus crash facts, 2008. 

    Science.gov (United States)

    2010-03-01

    This annual edition of Large Truck and Bus Crash Facts contains descriptive statistics about fatal, injury, and : property damage only crashes involving large trucks and buses in 2008. Selected crash statistics on passenger : vehicles are also presen...

  19. The influence of extratropical cloud phase and amount feedbacks on climate sensitivity

    Science.gov (United States)

    Frey, William R.; Kay, Jennifer E.

    2018-04-01

    Global coupled climate models have large long-standing cloud and radiation biases, calling into question their ability to simulate climate and climate change. This study assesses the impact of reducing shortwave radiation biases on climate sensitivity within the Community Earth System Model (CESM). The model is modified by increasing supercooled cloud liquid to better match absorbed shortwave radiation observations over the Southern Ocean while tuning to reduce a compensating tropical shortwave bias. With a thermodynamic mixed-layer ocean, equilibrium warming in response to doubled CO2 increases from 4.1 K in the control to 5.6 K in the modified model. This 1.5 K increase in equilibrium climate sensitivity is caused by changes in two extratropical shortwave cloud feedbacks. First, reduced conversion of cloud ice to liquid at high southern latitudes decreases the magnitude of a negative cloud phase feedback. Second, warming is amplified in the mid-latitudes by a larger positive shortwave cloud feedback. The positive cloud feedback, usually associated with the subtropics, arises when sea surface warming increases the moisture gradient between the boundary layer and free troposphere. The increased moisture gradient enhances the effectiveness of mixing to dry the boundary layer, which decreases cloud amount and optical depth. When a full-depth ocean with dynamics and thermodynamics is included, ocean heat uptake preferentially cools the mid-latitude Southern Ocean, partially inhibiting the positive cloud feedback and slowing warming. Overall, the results highlight strong connections between Southern Ocean mixed-phase cloud partitioning, cloud feedbacks, and ocean heat uptake in a climate forced by greenhouse gas changes.

  20. Systemic involvement in localized scleroderma/morphea.

    Science.gov (United States)

    Gorkiewicz-Petkow, Anna; Kalinska-Bienias, Agnieszka

    2015-01-01

    Localized scleroderma (LoSc), also known as morphea, is a rare fibrosing disorder of the skin and underlying tissues. Sclerosis is mainly limited to the skin, but subcutaneous tissue, fascia, and underlying muscles and bone may also be involved. In some cases, systemic manifestation with visceral abnormalities may occur. Several publications have focused on significant aspects of LoSc: genetics, immunity, epidemiology, scoring systems, and unification of classifications. Clinical studies featuring large cohorts with the disease published by various international study groups have been of great value in furthering the diagnostic and therapeutic management of LoSc. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Reading motivation, reading amount, and text comprehension in deaf and hearing adults.

    Science.gov (United States)

    Parault, Susan J; Williams, Heather M

    2010-01-01

    The purpose of this study is to examine the relationship between the variables of reading motivation, reading amount, and text comprehension in deaf and hearing adults. Research has shown that less than 50% of deaf students leave high school reading at or above a fourth-grade level (Allen, 1994). Our question is, how does this affect the levels of reading motivation and amount of reading in which deaf adults engage? Assessments of 30 hearing and 24 deaf adults showed that deaf participants reported significantly higher levels of reading motivation despite having been found to read at less than a sixth-grade level. No significant difference in the amount of reading between hearing and deaf adults was found. Amount of reading for personal reasons was found to be the best predictor of text comprehension in the deaf participants, and intrinsic motivation was found to be the best predictor of amount of reading in the deaf participants.

  2. Justification of novel practices involving radiation exposure

    International Nuclear Information System (INIS)

    Webb, G.; Boal, T.; Mason, C.; Wrixon, T.

    2006-01-01

    The concept of 'justification' of practices has been one of the three basic principles of radiation protection for many decades. The principle is simple in essence - that any practice involving radiation exposure should do more good than harm. There is no doubt that the many uses of radiation in the medical field and in industry generally satisfy this principle, yielding benefits that could not be achieved using other techniques; examples include CT scanning and industrial radiography. However, even in the early period after the introduction of the justification principle, there were practices for which the decision on justification was not clear and for which different decisions were made by the authorities in different countries. Many of these involved consumer products such as luminous clocks and watches, telephone dials, smoke detectors, lightning preventers and gas mantles. In most cases, these practices were relatively small scale and did not involve large exposures of either individual workers or members of the public. Decisions on justification were therefore often made by the regulator without extensive national debate. Over recent years, several practices have been proposed and undertaken that involve exposure to radiation for purposes that were generally not envisaged when the current system of radiation protection was created. Some of these practices were reviewed during a recent symposium held in Dublin, Ireland and involve, for example, the x-raying of people for theft detection purposes, for detection of weapons or contraband, for the prediction of physical development of young athletes or dancers, for age determination, for insurance purposes and in cases of suspected child abuse. It is particularly in the context of such novel practices that the need has emerged for clearer international guidance on the application of the justification principle. This paper reviews recent activities of the IAEA with respect to these issues, including the

  3. Justification of novel practices involving radiation exposure

    Energy Technology Data Exchange (ETDEWEB)

    Webb, G. [Radiation Protection Consul tant, Brighton (United Kingdom); Boal, T.; Mason, C.; Wrixon, T. [International Atomic Energy Agency, Vienna (Austria)

    2006-07-01

    The concept of 'justification' of practices has been one of the three basic principles of radiation protection for many decades. The principle is simple in essence - that any practice involving radiation exposure should do more good than harm. There is no doubt that the many uses of radiation in the medical field and in industry generally satisfy this principle, yielding benefits that could not be achieved using other techniques; examples include CT scanning and industrial radiography. However, even in the early period after the introduction of the justification principle, there were practices for which the decision on justification was not clear and for which different decisions were made by the authorities in different countries. Many of these involved consumer products such as luminous clocks and watches, telephone dials, smoke detectors, lightning preventers and gas mantles. In most cases, these practices were relatively small scale and did not involve large exposures of either individual workers or members of the public. Decisions on justification were therefore often made by the regulator without extensive national debate. Over recent years, several practices have been proposed and undertaken that involve exposure to radiation for purposes that were generally not envisaged when the current system of radiation protection was created. Some of these practices were reviewed during a recent symposium held in Dublin, Ireland and involve, for example, the x-raying of people for theft detection purposes, for detection of weapons or contraband, for the prediction of physical development of young athletes or dancers, for age determination, for insurance purposes and in cases of suspected child abuse. It is particularly in the context of such novel practices that the need has emerged for clearer international guidance on the application of the justification principle. This paper reviews recent activities of the IAEA with respect to these issues, including the

  4. Spent fuel transportation accident: a state's involvement

    International Nuclear Information System (INIS)

    Neuweg, M.

    1978-01-01

    On February 9, 1978 at 8:20 p.m., the duty officer for the Illinois Radiological Assistance Team was notified that a shipment containing uranium and plutonium was involved in an accident near Gibson City, Illinois on Route 54. It was reported that a pig containing an unknown amount of uranium and plutonium was involved. The Illinois District 6A State Police were called to the scene and secured the area. The duty officer in the meantime learned after numerous telephone calls, approximately 1 hour after the first notice was received, that the pig actually was a 48,000 pound cask containing 6 spent fuel rods and the tractor-trailer had split apart and was blocking one lane of the highway. The shipment had departed from Dresden Nuclear Power Station, Morris, Illinois, enroute to Babcox and Wilcox in Lynchburg, Virginia. Initial reports indicated the vehicle had split apart. Actually, the semi-trailer bed had buckled beneath the cask due to apparent excess stress. The cask remained entirely intact and was not damaged, but the state highway was closed to traffic. The State Radiological Assistance Team was dispatched and arrived on the scene at 12:45 a.m. Immediate radiation monitoring revealed a reading of 4 milliroentgen per hour at 10 feet from the cask. No contamination existed nor was anyone exposed to radiation unnecessarily. The cask was transferred to a Tri-State semi-trailer vehicle the following morning at approximately 6:30 a.m. At 9:30 a.m., February 10, the new vehicle was again enroute to its destination. This incident demonstrated typical occurrences involving transportation radiation accident: misinformation and/or lack of information on the initial response notification, inaccuracies of radiation monitorings at the scene of the accident, inconsistencies concerning the occurrences of the accident and unfamiliar terminology utilized by personnel first on the scene, i.e., pig, cask, vehicle split apart, etc

  5. Biosynthesis of promatrix metalloproteinase-9/chondroitin sulphate proteoglycan heteromer involves a Rottlerin-sensitive pathway.

    Directory of Open Access Journals (Sweden)

    Nabin Malla

    Full Text Available BACKGROUND: Previously we have shown that a fraction of the matrix metalloproteinase-9 (MMP-9 synthesized by the macrophage cell line THP-1 was bound to a chondroitin sulphate proteoglycan (CSPG core protein as a reduction sensitive heteromer. Several biochemical properties of the enzyme were changed when it was bound to the CSPG. METHODOLOGY/PRINCIPAL FINDINGS: By use of affinity chromatography, zymography, and radioactive labelling, various macrophage stimulators were tested for their effect on the synthesis of the proMMP-9/CSPG heteromer and its components by THP-1 cells. Of the stimulators, only PMA largely increased the biosynthesis of the heteromer. As PMA is an activator of PKC, we determined which PKC isoenzymes were expressed by performing RT-PCR and Western Blotting. Subsequently specific inhibitors were used to investigate their involvement in the biosynthesis of the heteromer. Of the inhibitors, only Rottlerin repressed the biosynthesis of proMMP-9/CSPG and its two components. Much lower concentrations of Rottlerin were needed to reduce the amount of CSPG than what was needed to repress the synthesis of the heteromer and MMP-9. Furthermore, Rottlerin caused a minor reduction in the activation of the PKC isoenzymes δ, ε, θ and υ (PKD3 in both control and PMA exposed cells. CONCLUSIONS/SIGNIFICANCE: The biosynthesis of the proMMP-9/CSPG heteromer and proMMP-9 in THP-1 cells involves a Rottlerin-sensitive pathway that is different from the Rottlerin sensitive pathway involved in the CSPG biosynthesis. MMP-9 and CSPGs are known to be involved in various physiological and pathological processes. Formation of complexes may influence both the specificity and localization of the enzyme. Therefore, knowledge about biosynthetic pathways and factors involved in the formation of the MMP-9/CSPG heteromer may contribute to insight in the heteromers biological function as well as pointing to future targets for therapeutic agents.

  6. Sample-path large deviations in credit risk

    NARCIS (Netherlands)

    Leijdekker, V.J.G.; Mandjes, M.R.H.; Spreij, P.J.C.

    2011-01-01

    The event of large losses plays an important role in credit risk. As these large losses are typically rare, and portfolios usually consist of a large number of positions, large deviation theory is the natural tool to analyze the tail asymptotics of the probabilities involved. We first derive a

  7. Renal involvement in behcet's disease

    International Nuclear Information System (INIS)

    Ardalan, Mohammad Reza; Noshad, Hamid; Sadreddini, Shahram; Ebrahimi, Aliasghar; Molaeefard, Mahsheed; Somi, Mohammad Hossein; Shoja, Mohammadali Mohajel

    2009-01-01

    There are conflicting reports about the renal involvement in Behcet's disease (BD). In this study we aimed to study the frequency and type of renal involvement in a group of patients with BD in Azerbaijan province that is one of the prevalent areas of BD in Iran. All cases of BD were prospectively followed between June 2004 and January 2007, and evaluated for renal dys-function (serum creatinine > 1.7 mg/dL), glomerular hematuria and proteinuria. Those patients with proteinuria > 500 mg/day and serum creatinine level > 2 mg/dL, underwent renal biopsy. From a total number of 100 patients, six patients (6%) had obvious renal involvements. Four patients had glomerular hematuria and proteinuria. Renal biopsy in two of them revealed measangial proliferative glumerulonephritis with IgA deposit in one of them and membranoproliferative glumerolonephritis in another one. Two remaining patients had serum creatinine > 2 mg/dL without any hematuria or proteinuria. Serologic study for viral agents and collagen vascular disease were negative in all patients with renal involvements. In conclusion, renal involvement in BD is not infrequent, although in most cases it is mild in nature and may be missed. (author)

  8. Respiratory muscle involvement in sarcoidosis.

    Science.gov (United States)

    Schreiber, Tina; Windisch, Wolfram

    2018-07-01

    In sarcoidosis, muscle involvement is common, but mostly asymptomatic. Currently, little is known about respiratory muscle and diaphragm involvement and function in patients with sarcoidosis. Reduced inspiratory muscle strength and/or a reduced diaphragm function may contribute to exertional dyspnea, fatigue and reduced health-related quality of life. Previous studies using volitional and non-volitional tests demonstrated a reduced inspiratory muscle strength in sarcoidosis compared to control subjects, and also showed that respiratory muscle function may even be significantly impaired in a subset of patients. Areas covered: This review examines the evidence on respiratory muscle involvement and its implications in sarcoidosis with emphasis on pathogenesis, diagnosis and treatment of respiratory muscle dysfunction. The presented evidence was identified by a literature search performed in PubMed and Medline for articles about respiratory and skeletal muscle function in sarcoidosis through to January 2018. Expert commentary: Respiratory muscle involvement in sarcoidosis is an underdiagnosed condition, which may have an important impact on dyspnea and health-related quality of life. Further studies are needed to understand the etiology, pathogenesis and extent of respiratory muscle involvement in sarcoidosis.

  9. Calculation device for amount of heavy element nuclide in reactor fuels and calculation method therefor

    International Nuclear Information System (INIS)

    Naka, Takafumi; Yamamoto, Munenari.

    1995-01-01

    When there are two or more origins of deuterium nuclides in reactor fuels, there are disposed a memory device for an amount of deuterium nuclides for every origin in a noted fuel segment at a certain time point, a device for calculating the amount of nuclides for every origin and current neutron fluxes in the noted fuel segment, and a device for separating and then displaying the amount of deuterium nuclides for every origin. Equations for combustion are dissolved for every origin of the deuterium nuclides based on the amount of the deuterium nuclides for every origin and neutron fluxes, to calculate the current amount of deuterium nuclides for every origin. The amount of deuterium nuclides originated from uranium is calculated ignoring α-decay of curium, while the amount of deuterium nuclides originated from plutonium is calculated ignoring the generation of plutonium formed from neptunium. Deuterium nuclides can be measured and controlled accurately for every origin of the reactor fuels. Even when nuclear fuel materials have two or more nationalities, the measurement and control thereof can be conducted for every country. (N.H.)

  10. A large-scale application of the Kalman alignment algorithm to the CMS tracker

    International Nuclear Information System (INIS)

    Widl, E; Fruehwirth, R

    2008-01-01

    The Kalman alignment algorithm has been specifically developed to cope with the demands that arise from the specifications of the CMS Tracker. The algorithmic concept is based on the Kalman filter formalism and is designed to avoid the inversion of large matrices. Most notably, the algorithm strikes a balance between conventional global and local track-based alignment algorithms, by restricting the computation of alignment parameters not only to alignable objects hit by the same track, but also to all other alignable objects that are significantly correlated. Nevertheless, this feature also comes with various trade-offs: Mechanisms are needed that affect which alignable objects are significantly correlated and keep track of these correlations. Due to the large amount of alignable objects involved at each update (at least compared to local alignment algorithms), the time spent for retrieving and writing alignment parameters as well as the required user memory becomes a significant factor. The large-scale test presented here applies the Kalman alignment algorithm to the (misaligned) CMS Tracker barrel, and demonstrates the feasibility of the algorithm in a realistic scenario. It is shown that both the computation time and the amount of required user memory are within reasonable bounds, given the available computing resources, and that the obtained results are satisfactory

  11. Inclusive Briefing and User Involvement

    DEFF Research Database (Denmark)

    Jensen, Per Anker

    2011-01-01

    Briefing is not just about specifying needs as requirements but also about evaluating how well design proposals fulfil needs and aspirations. Furthermore, briefing is not only about building design. Briefing starts at the preproject stage to create a basis for the project decision and can include...... by top management. The article describes the briefing processes and the methods for user involvement, identifies problem areas and points out possible improvements. The author was actively involved in the project as deputy project director, with responsibility for the briefing process, and is now...... includes a literature study on briefing and user involvement in building projects, and presents a case study of a major building project of a new headquarters and media centre for the Danish Broadcasting Corporation in Copenhagen. The building project was actively used as part of a corporate change process...

  12. Drug involvement in fatal overdoses

    Directory of Open Access Journals (Sweden)

    Christopher J. Ruhm

    2017-12-01

    Full Text Available Death certificate data from the Multiple Cause of Death (MCOD files were analyzed to better understand the drug categories most responsible for the increase in fatal overdoses occurring between 1999 and 2014. Statistical adjustment methods were used to account for the understatement in reported drug involvement occurring because death certificates frequently do not specify which drugs were involved in the deaths. The frequency of combination drug use introduced additional uncertainty and so a distinction was made between any versus exclusive drug involvement. Many results were sensitive to the starting and ending years chosen for examination. Opioid analgesics played a major role in the increased drug deaths for analysis windows starting in 1999 but other drugs, particularly heroin, became more significant for recent time periods. Combination drug use was important for all time periods and needs to be accounted for when designing policies to slow or reverse the increase in overdose deaths.

  13. User involvement in care work

    DEFF Research Database (Denmark)

    Dybbroe, Betina; Kamp, Annette

    In recent years user involvement has become a paradigm for transforming the health and social care sector. This development–also labelled empowerment, co-creation, partnership, patient-centeredness - is seen as a means to reform organizations in ways that enhance quality, economic cost effectiven...... forms of professionalism, and imply tensions in health and social care work.......In recent years user involvement has become a paradigm for transforming the health and social care sector. This development–also labelled empowerment, co-creation, partnership, patient-centeredness - is seen as a means to reform organizations in ways that enhance quality, economic cost...... addressed the way this paradigm affects the users, in specific sectors. However user involvement also affects working life. It may imply change and redistribution of tasks and identities between users and professionals, and may also transform the relations of care. In this paper we explore the possible...

  14. User interface and patient involvement.

    Science.gov (United States)

    Andreassen, Hege Kristin; Lundvoll Nilsen, Line

    2013-01-01

    Increased patient involvement is a goal in contemporary health care, and of importance to the development of patient oriented ICT. In this paper we discuss how the design of patient-user interfaces can affect patient involvement. Our discussion is based on 12 semi-structured interviews with patient users of a web-based solution for patient--doctor communication piloted in Norway. We argue ICT solutions offering a choice of user interfaces on the patient side are preferable to ensure individual accommodation and a high degree of patient involvement. When introducing web-based tools for patient--health professional communication a free-text option should be provided to the patient users.

  15. Strategy Innovation with Employee Involvement

    DEFF Research Database (Denmark)

    Friis, Ole Uhrskov; Koch, Christian

    2015-01-01

    The purpose of this article is to investigate how employees can be involved in strategy innovation processes and how new strategy practices (new tools and procedures) are used to change strategy praxis in order to sustain value creation. In the strategizing actions, we found that even...... if the managers still dominate, some processes of direct involvement of employees occur, in particular when employees are asked to supplement overall strategic goals and when they directly shape several sub-strategies. Strategy practices found include strategy planning, an open space workshop and organised...... strategy projects. Especially the latter two are important in facilitating the employee involvement. The case, however, also exhibits enterprise-situated praxises related to unplanned events, like the mitigation of taboos....

  16. Safe handling of kilogram amounts of fuel-grade plutonium and of gram amounts of plutonium-238, americium-241 and curium-244

    International Nuclear Information System (INIS)

    Louwrier, K.P.; Richter, K.

    1976-01-01

    During the past 10 years about 600 glove-boxes have been installed at the Institute for Transuranium Elements at Karlsruhe. About 80% of these glove-boxes have been designed and equipped for handling 100-g to 1-kg amounts of 239 Pu containing 8-12% 240 Pu (low-exposure plutonium). A small proportion of the glove-boxes is equipped with additional shielding in the form of lead sheet or lead glass for work with recycled plutonium. In these glove-boxes gram-amounts of 241 Am have also been handled for preparation of Al-Am targets using tongs and additional shielding inside the glove-boxes themselves. Water- and lead-shielded glove-boxes equipped with telemanipulators have been installed for routine work with gram-amounts of 241 Am, 243 Am and 244 Cm. A prediction of the expected radiation dose for the personnel is difficult and only valid for a preparation procedure with well-defined preparation steps, owing to the fact that gamma dose-rates depend strongly upon proximity and source seize. Gamma radiation dose measurements during non-routine work for 241 Am target preparation showed that handling of gram amounts leads to a rather high irradiation dose for the personnel, despite lead or steel glove-box shielding and shielding within the glove-boxes. A direct glove-hand to americium contact must be avoided. For all glove-handling of materials with gamma radiation an irradiation control of the forearms of the personnel by, for example, thermoluminescence dosimeters is necessary. Routine handling of americium and curium should be executed with master-slave equipment behind neutron and gamma shielding. (author)

  17. China's Involvement in Economic Globalization

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ As China's fast-growing economy attracts the world's largest multinational companies to pour billions of dollars into the nation to capitalize on the business opportunities. China's companies, for their part, have also significantly increased the amount of their overseas investment. Research data recently released shows that, through mid-October, there were 43investment deals made by Chinese companies, up from 39 for all of last year. The total value of the deals, which were mergers and acquisitions overseas, was US$1.93 billion, compared with US$2.2 billion for all of 2003.

  18. Sorption of small amounts of europium(III) on iron(III) hydroxide and oxide

    International Nuclear Information System (INIS)

    Music, S.; Gessner, M.; Wolf, R.H.H.

    1979-01-01

    The sorption of small amounts of europium(III) on iron(III) hydroxide and oxide has been studied as a function of pH. The mechanism of sorption is discussed. Optimum conditions have been found for the preconcentration of small or trace amounts of europium(III) by iron(III) hydroxide and oxide. The influence of complexing agents (EDTA, oxalate, tartrate and 5-sulfosalicylic acid) on the sorption of small amounts of europium(III) on iron(III) oxide has also been studied. (author)

  19. Vertebral osteomyelitis without disc involvement

    Energy Technology Data Exchange (ETDEWEB)

    Kamani, I.; Syed, I.; Saifuddin, A. E-mail: asaifuddin@aol.com; Green, R.; MacSweeney, F

    2004-10-01

    Vertebral osteomyelitis is most commonly due to pyogenic or granulomatous infection and typically results in the combined involvement of the intervertebral disc and adjacent vertebral bodies. Non-infective causes include the related conditions of chronic recurrent multifocal osteomyelitis (CRMO) and SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome. Occasionally, these conditions may present purely within the vertebral body, resulting in various combinations of vertebral marrow oedema and sclerosis, destructive lesions of the vertebral body and pathological vertebral collapse, thus mimicking neoplastic disease. This review illustrates the imaging features of vertebral osteomyelitis without disc involvement, with emphasis on magnetic resonance imaging (MRI) findings.

  20. Multisystem involvement in neuromyelitis optica

    Directory of Open Access Journals (Sweden)

    Megan M Langille

    2015-01-01

    Full Text Available We describe a case of pediatric neuromyelitis optica (NMO with muscle and lung involvement in addition to central nervous system disease. Our patient initially presented with features of area postrema syndrome, then subsequently with optic neuritis. The patient also had recurrent hyperCKemia that responded to corticosteroids. Finally, axillary and hilar adenopathy with pulmonary consolidation were noted as well and responded to immunomodulation. Our case highlights multisystem involvement in NMO including non-infectious pulmonary findings which have not been described in the pediatric population previously.

  1. Guidance on accidents involving radioactivity

    International Nuclear Information System (INIS)

    1989-01-01

    This annex contains advice to Health Authorities on their response to accidents involving radioactivity. The guidance is in six parts:-(1) planning the response required to nuclear accidents overseas, (2) planning the response required to UK nuclear accidents a) emergency plans for nuclear installations b) nuclear powered satellites, (3) the handling of casualties contaminated with radioactive substances, (4) background information for dealing with queries from the public in the event of an accident, (5) the national arrangements for incident involving radioactivity (NAIR), (6) administrative arrangements. (author)

  2. Involving Employees in Strategy innovation

    DEFF Research Database (Denmark)

    Friis, Ole Uhrskov; Koch, Christian

    2011-01-01

    Strategy as a practice and continuous innovation approaches are combined to conceptualise dilemmas of short versus long term and to analyse a case of employee participation as a particular example of strategy innovation. The case is a medium size textile company developing its strategy involving ...... and Balanced Score Card consultancy, an ‘open space’ workshop and organized strategy projects. Especially the latter two are important in facilitating the employee involvement. The case however also exhibit enterprise situated praxis’s like mitigation of taboos....

  3. Extrapulmonary involvement in pediatric tuberculosis.

    Science.gov (United States)

    Kritsaneepaiboon, Supika; Andres, Mariaem M; Tatco, Vincent R; Lim, Cielo Consuelo Q; Concepcion, Nathan David P

    2017-09-01

    Tuberculosis in childhood is clinically challenging, but it is a preventable and treatable disease. Risk factors depend on age and immunity status. The most common form of pediatric tuberculosis is pulmonary disease, which comprises more than half of the cases. Other forms make up the extrapulmonary tuberculosis that involves infection of the lymph nodes, central nervous system, gastrointestinal system, hepatobiliary tree, and renal and musculoskeletal systems. Knowledge of the imaging characteristics of pediatric tuberculosis provides clues to diagnosis. This article aims to review the imaging characteristics of common sites for extrapulmonary tuberculous involvement in children.

  4. Large mass storage facility

    International Nuclear Information System (INIS)

    Peskin, A.M.

    1978-01-01

    The report of a committee to study the questions surrounding possible acquisition of a large mass-storage device is presented. The current computing environment at BNL and justification for an online large mass storage device are briefly discussed. Possible devices to meet the requirements of large mass storage are surveyed, including future devices. The future computing needs of BNL are prognosticated. 2 figures, 4 tables

  5. Using technology to support investigations in the electronic age: tracking hackers to large scale international computer fraud

    Science.gov (United States)

    McFall, Steve

    1994-03-01

    With the increase in business automation and the widespread availability and low cost of computer systems, law enforcement agencies have seen a corresponding increase in criminal acts involving computers. The examination of computer evidence is a new field of forensic science with numerous opportunities for research and development. Research is needed to develop new software utilities to examine computer storage media, expert systems capable of finding criminal activity in large amounts of data, and to find methods of recovering data from chemically and physically damaged computer storage media. In addition, defeating encryption and password protection of computer files is also a topic requiring more research and development.

  6. Study of the influence of the amount of PBI-H{sub 3}PO{sub 4} in the catalytic layer of a high temperature PEMFC

    Energy Technology Data Exchange (ETDEWEB)

    Lobato, Justo; Canizares, Pablo; Rodrigo, Manuel A.; Linares, Jose J.; Pinar, F. Javier [Chemical Engineering Department, Enrique Costa Building, University of Castilla-La Mancha, Av. Camilo Jose Cela, n 12, 13071, Ciudad Real (Spain)

    2010-02-15

    The influence of the amount of polybenzimidazole (PBI)-H{sub 3}PO{sub 4} (normalized with respect to the PBI loading, which expressed as C/PBI weight ratio) content in both the anode and cathode has been studied for a PBI-based high temperature proton exchange membrane (PEM) fuel cell. The electrodes prepared with different amounts of PBI have been characterized physically, by measuring the pore size distribution, and visualizing the surface microstructure. Afterwards, the electrochemical behaviour of the electrodes has been evaluated. The catalytic electrochemical activity has been measured by voltamperometry for each electrode prepared with a different PBI content, and the cell performance results have been studied, supported by the impedance spectra, in order to determine the influence of the PBI loading in each electrode. The best results have been achieved with a C/PBI weight ratio of 20, for both the anode and the cathode. A lower C/PBI weight ratio (larger amount of PBI in the catalytic layer) reduced the electrocatalytic activity, and impaired the mass transport processes, due to the large amount of polymer covering the catalyst particle, lowering the cell performance. A higher C/PBI weight ratio (lower amount of PBI in the catalytic layer) reduced the electrocatalytic activity, and slightly increased the ohmic resistance. The low amount of the polymeric ionic carrier PBI-H{sub 3}PO{sub 4} limited the proton mobility, despite of the presence of large amounts of ''free'' H{sub 3}PO{sub 4} in the catalytic layer. (author)

  7. Putaminal involvement in Rasmussen encephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Rajesh, Bhagavatheeswaran; Ashalatha, Radhakrishnan [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Neurology, Trivandrum, Kerala (India); Kesavadas, Chandrasekharan; Thomas, Bejoy [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Imaging Sciences and Interventional Radiology, Trivandrum, Kerala (India)

    2006-08-15

    Rasmussen encephalitis (RE) is a rare devastating disease of childhood causing progressive neurological deficits and intractable seizures, typically affecting one hemisphere. Characteristic MRI features include progressive unihemispheric focal cortical atrophy and grey- or white-matter high-signal changes and basal ganglion involvement, particularly of the caudate nucleus. To analyse the pattern of involvement of different brain structures in a series of patients with RE and to attempt clinical correlation. We reviewed the medical records and neuroimaging data of 12 patients diagnosed with RE satisfying the European Consensus Statement diagnostic criteria. The disease manifested as seizures in all patients and was refractory; epilepsia partialis continua was a notable feature (nine patients). Hemiparesis of varying grades was noted in all but one patient; none had extrapyramidal signs. Neuroimaging showed cortical involvement in the insular/periinsular regions in 11 patients. Caudate atrophy was noted in ten patients. Putaminal atrophy was seen in nine patients, six of whom had additional hyperintense signal changes. Our study highlights frequent putaminal atrophy and signal changes in RE, which suggests a more extensive basal ganglion involvement than emphasized previously. Recognition of putaminal changes may be a useful additional tool in the radiological diagnosis of RE. (orig.)

  8. Managing Parent Involvement during Crisis

    Science.gov (United States)

    Merriman, Lynette S.

    2008-01-01

    In the wake of 9/11, Hurricane Katrina, and the Virginia Tech shooting tragedy, it is no surprise that concern for students' safety is the primary reason attributed to parents' increased involvement. Parents and university administrators share in their commitment to student safety. However, college and university staff who assume responsibility…

  9. Community Involvement in TB Research

    NARCIS (Netherlands)

    M. van der Werf (Marloes); S.G. Heumann (Silke); E.M.H. Mitchell

    2011-01-01

    textabstractWhile communities at risk have been both drivers and partners in HIV research, their important role in TB research is yet to be fully realized. Involvement of communities in tuberculosis care and prevention is currently on the international agenda. This creates opportunities and

  10. Putaminal involvement in Rasmussen encephalitis

    International Nuclear Information System (INIS)

    Rajesh, Bhagavatheeswaran; Ashalatha, Radhakrishnan; Kesavadas, Chandrasekharan; Thomas, Bejoy

    2006-01-01

    Rasmussen encephalitis (RE) is a rare devastating disease of childhood causing progressive neurological deficits and intractable seizures, typically affecting one hemisphere. Characteristic MRI features include progressive unihemispheric focal cortical atrophy and grey- or white-matter high-signal changes and basal ganglion involvement, particularly of the caudate nucleus. To analyse the pattern of involvement of different brain structures in a series of patients with RE and to attempt clinical correlation. We reviewed the medical records and neuroimaging data of 12 patients diagnosed with RE satisfying the European Consensus Statement diagnostic criteria. The disease manifested as seizures in all patients and was refractory; epilepsia partialis continua was a notable feature (nine patients). Hemiparesis of varying grades was noted in all but one patient; none had extrapyramidal signs. Neuroimaging showed cortical involvement in the insular/periinsular regions in 11 patients. Caudate atrophy was noted in ten patients. Putaminal atrophy was seen in nine patients, six of whom had additional hyperintense signal changes. Our study highlights frequent putaminal atrophy and signal changes in RE, which suggests a more extensive basal ganglion involvement than emphasized previously. Recognition of putaminal changes may be a useful additional tool in the radiological diagnosis of RE. (orig.)

  11. Corporate Involvement in C AI

    Science.gov (United States)

    Baker, Justine C.

    1978-01-01

    Historic perspective of computer manufacturers and their contribution to CAI. Corporate CAI products and services are mentioned, as is a forecast for educational involvement by computer corporations. A chart of major computer corporations shows gross sales, net earnings, products and services offered, and other corporate information. (RAO)

  12. Parental involvement and educational achievement

    NARCIS (Netherlands)

    Driessen, G.; Smit, F.; Sleegers, P.

    2005-01-01

    Parental involvement is seen as an important strategy for the advancement of the quality of education. The ultimate objective of this is to expand the social and cognitive capacities of pupils. In addition, special attention is paid to the children of low-educated and ethnic minority parents.

  13. Eye involvement in haematological malignancies

    NARCIS (Netherlands)

    Riemens, J.A.

    2014-01-01

    This thesis describes the involvement of the eye in haematological malignancies and focuses on two topics; primary vitreoretinal lymphoma (PVRL) and ocular Graft-versus-Host Disease (GvHD). The aim of this thesis is first: to compare the efficacy of diverse treatment options of PVRL with regard to

  14. Effect of amount of glycine as fuel in obtaining nanocomposite Ni/NiO

    International Nuclear Information System (INIS)

    Simoes, A.N.; Simoes, V.N.; Neiva, L.S.; Quirino, M.R.; Vieira, D.A.; Gama, L.

    2010-01-01

    This paper proposes to investigate the effect of the amount of glycine in obtaining nanocomposite Ni/NiO synthesized by combustion reaction technique. The amount of glycine used was calculated on the stoichiometric composition of 50% and 100%. Characterizations by X-ray diffraction (XRD), N2 adsorption by the BET method and scanning electron microscopy (SEM) were performed with powder of Ni/NiO result. The analysis of X-ray diffraction showed the presence of crystalline NiO phase in the presence of nickel as a secondary phase, whose amount increased with the amount of glycine. Increasing the concentration of glycine also caused an increase in surface area, which ranged from 1.1 to 1.4 m 2 /g. The micrographs revealed the formation of soft agglomerates with porous appearance and easy dispersions. It can be concluded that the synthesis is effective to obtain nanosized powders. (author)

  15. Effect of Modified Rubber Particles Mixing Amount on Properties of Cement Mortar

    Directory of Open Access Journals (Sweden)

    Gang Xue

    2017-01-01

    Full Text Available The crumb rubber cement mortar is prepared by the crumb rubber aggregates in 60 mesh which are modified by 1% polyvinyl alcohol (PVA solution. Some mechanical properties of cement mortar with different crumb rubber aggregate amounts are researched including compressive strength, flexural strength, the ratio of compressive strength to flexural strength, impact resistance, and dry contraction percentage. In our tests, we consider six kinds of the rubber contents, 0%, 7.5%, 15%, 19%, 22.5%, and 30%, respectively. The optimal mixing amount of crumb rubber is determined by measuring three indices, the ratio of compressive strength to flexural strength, impact resistance, and dry contraction percentage. It is shown by test that the ratio of compressive strength to flexural strength is the smallest when the mixing amount of rubber is 19%; meanwhile high impact resistance and rational drying shrinkage are observed. The optimal mixing amount of the rubber particles is 19% determined by this test.

  16. Measuring method for amount of fissionable gas in spent fuel pellet

    International Nuclear Information System (INIS)

    Kashibe, Shinji.

    1992-01-01

    The method of the present invention separately measures the amount of both of a fission product (FP) gas accumulated in bubbles at the crystal grain boundary of spent fuel pellets and an FP gas accumulated in the crystal grains. That is, in a radial position of the spent fuel pellet, a microfine region is mechanically destroyed. The amount of the FP gas released by the destruction from the crystal grains is measured by using a mass analyzer. Then, when the destroyed pieces formed by the destruction are recovered and dissolved, FP gas accumulated in the crystal grains of the pellet is released. The amount released is measured by the mass analyzer. With such procedures, the amount of FP gas accumulated in the bubbles at the crystal grain boundary and in the crystal grains at the radial position of the spent fuel pellet can be measured discriminately. Accordingly, the integrity of the fuel pellet can be recognized appropriately. (I.S.)

  17. 26 CFR 1.911-3 - Determination of amount of foreign earned income to be excluded.

    Science.gov (United States)

    2010-04-01

    ... country based on the productivity of the employees in that country. M pays a bonus to employees in country... amounts attributable to services performed in 1982 may be used in calculating A's section 911(a)(1...

  18. PBGC Amount in Pay Per State for US and US Territories (2016) Single-Employer Program

    Data.gov (United States)

    Pension Benefit Guaranty Corporation — Provides customer counts and amounts paid to customers in the previous calendar year for customers of pension plans trusteed by the PBGC under its single-employer...

  19. 9 CFR 51.24 - Maximum per-head indemnity amounts.

    Science.gov (United States)

    2010-01-01

    ... indemnity for their animals. All animals must be individually appraised to determine their fair market value. The indemnity amount will be the appraised value minus the salvage value of the animal, up to a...

  20. Determining Original Inventory Amount of Radioactive Substances from Unmonitored Radionuclide Emissions

    International Nuclear Information System (INIS)

    Hamilton, J.T.; Blunt, B.C.

    1999-01-01

    The purpose of this document is to determine the air emissions inventory of the Savannah River Site. To satisfy regulatory requirements, a new equation has been developed to determine original inventory amounts from unmonitored radionuclide emissions