Physics investigate the forces of nature

CERN Document Server

Gardner, Jane

2014-01-01

Have you ever noticed that the physical world works in certain ways? Skateboarders use force and motion to perform tricks. If you jump up as high as you can, you'll quickly fall back to the ground. Baseball players use gravity to bring the ball back down when they throw it. When you flip a switch, electricity powers your toaster. Rock bands use electricity to put on a show. The fascinating science of physics helps you understand why forces, motion, gravity, electricity, light, and sound work in predictable ways. Combining inquiry-based activities with physics topics, Physics: Investigate the Forces of Nature features graphic novel illustrations, fascinating sidebars, youtube links, and a glossary of important vocabulary to illuminate the complex world of physics and bring it to life. Projects include designing a skateboard park that maps the forces at work on the skateboarder and the skateboard, and creating a stage design for a rock band that places electric current where it is needed. Additional materials i...

The International Criminal Court: Considerations for the Joint Force Commander

National Research Council Canada - National Science Library

Sutton, Michael

2003-01-01

An analysis of the issues and remedies a Joint Force Commander should be concerned about because of the relationship between the United States and the newly-created International Criminal Court (ICC...

EFFECTS OF COLUMN FAILURES ON THE INTERNAL FORCES OF ORTHOGONAL REINFORCED CONCRETE BUILDING FRAMES

Directory of Open Access Journals (Sweden)

Nilay KAYA

2006-02-01

Full Text Available In this study, the effects of column failures which may take place due to the special causes such as blast, vehicle impact, insufficient or deficient design, on the internal forces of orthogonal reinforced concrete building frames have been investigated. Calculations have been performed with SAP2000 structural analysis program, under static conditions. For a typical frame system, firstly, various column failure scenarios have been considered for uninfilled case and internal forces have been calculated and compared with those in the intact case. Then, similar calculations have been implemented for the case of presence of infill walls. The results of analyses have shown that the effects of column failures had condensed on the neighbor columns and beams of orthogonal frames on which the columns had been failed. Moreover, it has been determined that, while the bending moment capacities of the connected beams to the failed columns had exceeded in the bare frames, in the masonry infilled frames, walls give substantial support to the structural elements of the building, and capacities of the beams had not exceeded.

The Prediction of Labor Force Status: Implications from International Adult Skill Assessments. Research Report. ETS RR-16-11

Science.gov (United States)

Li, Tongyun; von Davier, Matthias; Hancock, Gregory R.

2016-01-01

This report investigates the prediction of labor force status using observed variables, such as gender, age, and immigrant status, and more importantly, measured skill variables, including literacy proficiency and a categorical rating of educational attainment based on the 1994 International Adult Literacy Survey (IALS), the 2003 Adult Literacy…

Investigation of Calibrating Force Transducer Using Sinusoidal Force

International Nuclear Information System (INIS)

Zhang Li; Wang Yu; Zhang Lizhe

2010-01-01

Sinusoidal force calibration method was studied several years before at Physikalisch-Technische Bundesanstalt (PTB). A similar dynamic force calibration system is developed at Changcheng Institute of Metrology and Measurement (CIMM). It uses electro-dynamic shakers to generate dynamic force in the range from 1 N to 20 kN, and heterodyne laser interferometers are used for acceleration measurement. The force transducer to be calibrated is mounted on the shaker, and a mass block is screwed on the top of force transducer, the sinusoidal forces realized by accelerated load masses are traceable to acceleration and mass according to the force definition. The methods of determining Spatial-dependent acceleration on mass block and measuring the end mass of force transducer in dynamic force calibration are discussed in this paper.

Activation of biceps femoris long head reduces tibiofemoral anterior shear force and tibial internal rotation torque in healthy subjects.

Science.gov (United States)

Azmi, Nur Liyana; Ding, Ziyun; Xu, Rui; Bull, Anthony M J

2018-01-01

The anterior cruciate ligament (ACL) provides resistance to tibial internal rotation torque and anterior shear at the knee. ACL deficiency results in knee instability. Optimisation of muscle contraction through functional electrical stimulation (FES) offers the prospect of mitigating the destabilising effects of ACL deficiency. The hypothesis of this study is that activation of the biceps femoris long head (BFLH) reduces the tibial internal rotation torque and the anterior shear force at the knee. Gait data of twelve healthy subjects were measured with and without the application of FES and taken as inputs to a computational musculoskeletal model. The model was used to investigate the optimum levels of BFLH activation during FES gait in reducing the anterior shear force to zero. This study found that FES significantly reduced the tibial internal rotation torque at the knee during the stance phase of gait (p = 0.0322) and the computational musculoskeletal modelling revealed that a mean BFLH activation of 20.8% (±8.4%) could reduce the anterior shear force to zero. At the time frame when the anterior shear force was zero, the internal rotation torque was reduced by 0.023 ± 0.0167 Nm/BW, with a mean 188% reduction across subjects (p = 0.0002). In conclusion, activation of the BFLH is able to reduce the tibial internal rotation torque and the anterior shear force at the knee in healthy control subjects. This should be tested on ACL deficient subject to consider its effect in mitigating instability due to ligament deficiency. In future clinical practice, activating the BFLH may be used to protect ACL reconstructions during post-operative rehabilitation, assist with residual instabilities post reconstruction, and reduce the need for ACL reconstruction surgery in some cases.

Investigating the influence of anthropogenic forcing on observed mean and extreme sea level pressure trends over the Mediterranean Region.

Science.gov (United States)

Barkhordarian, Armineh

2012-01-01

We investigate whether the observed mean sea level pressure (SLP) trends over the Mediterranean region in the period from 1975 to 2004 are significantly consistent with what 17 models projected as response of SLP to anthropogenic forcing (greenhouse gases and sulphate aerosols, GS). Obtained results indicate that the observed trends in mean SLP cannot be explained by natural (internal) variability. Externally forced changes are detectable in all seasons, except spring. The large-scale component (spatial mean) of the GS signal is detectable in all the 17 models in winter and in 12 of the 17 models in summer. However, the small-scale component (spatial anomalies about the spatial mean) of GS signal is only detectable in winter within 11 of the 17 models. We also show that GS signal has a detectable influence on observed decreasing (increasing) tendency in the frequencies of extremely low (high) SLP days in winter and that these changes cannot be explained by internal climate variability. While the detection of GS forcing is robust in winter and summer, there are striking inconsistencies in autumn, where analysis points to the presence of an external forcing, which is not GS forcing.

Forced-air warming design: evaluation of intake filtration, internal microbial buildup, and airborne-contamination emissions.

Science.gov (United States)

Reed, Mike; Kimberger, Oliver; McGovern, Paul D; Albrecht, Mark C

2013-08-01

Forced-air warming devices are effective for the prevention of surgical hypothermia. However, these devices intake nonsterile floor-level air, and it is unknown whether they have adequate filtration measures to prevent the internal buildup or emission of microbial contaminants. We rated the intake filtration efficiency of a popular current-generation forced-air warming device (Bair Hugger model 750, Arizant Healthcare) using a monodisperse sodium chloride aerosol in the laboratory. We further sampled 23 forced-air warming devices (same model) in daily hospital use for internal microbial buildup and airborne-contamination emissions via swabbing and particle counting. Laboratory testing found the intake filter to be 63.8% efficient. Swabbing detected microorganisms within 100% of the forced-air warming blowers sampled, with isolates of coagulase-negative staphylococci, mold, and micrococci identified. Particle counting showed 96% of forced-air warming blowers to be emitting significant levels of internally generated airborne contaminants out of the hose end. These findings highlight the need for upgraded intake filtration, preferably high-efficiency particulate air filtration (99.97% efficient), on current-generation forced-air warming devices to reduce contamination buildup and emission risks.

Pilot investigation - Nominal crew induced forces in zero-g

Science.gov (United States)

Klute, Glenn K.

1992-01-01

This report presents pilot-study data of test subject forces induced by intravehicular activities such as push-offs and landings with both hands and feet. Five subjects participated in this investigation. Three orthogonal force axes were measured in the NASA KC-135 research aircraft's 'zero-g' environment. The largest forces were induced during vertical foot push-offs, including one of 534 newtons (120 lbs). The mean vertical foot push-off was 311 newtons (70 lbs). The vertical hand push-off forces were also relatively large, including one of 267 newtons (60 lbs) with a mean of 151 newtons (34 lbs). These force magnitudes of these forces would result in a Shuttle gravity environment of about 1 x exp 10 -4 g's.

External and internal influences as driving forces and/or stumbling ...

African Journals Online (AJOL)

The development of national and institutional quality assurance and management systems is often forced (rightfully or wrongly) into a specific direction by external and internal environmental influences. In South Africa such influences play a major role in both the national higher education policy developments and the ...

Internal and forced eddy variability in the Labrador Sea

Science.gov (United States)

Bracco, A.; Luo, H.; Zhong, Y.; Lilly, J.

2009-04-01

Water mass transformation in the Labrador Sea, widely believed to be one of the key regions in the Atlantic Meridional Overturning Circulation (AMOC), now appears to be strongly impacted by vortex dynamics of the unstable boundary current. Large interannual variations in both eddy shedding and buoyancy transport from the boundary current have been observed but not explained, and are apparently sensitive to the state of the inflowing current. Heat and salinity fluxes associated with the eddies drive ventilation changes not accounted for by changes in local surface forcing, particularly during occasional years of extreme eddy activity, and constitute a predominant source of "internal" oceanic variability. The nature of this variable eddy-driven restratification is one of the outstanding questions along the northern transformation pathway. Here we investigate the eddy generation mechanism and the associated buoyancy fluxes by combining realistic and idealized numerical modeling, data analysis, and theory. Theory, supported by idealized experiments, provides criteria to test hypotheses as to the vortex formation process (by baroclinic instability linked to the bottom topography). Ensembles of numerical experiments with a high-resolution regional model (ROMS) allow for quantifying the sensitivity of eddy generation and property transport to variations in local and external forcing parameters. For the first time, we reproduce with a numerical simulation the observed interannual variability in the eddy kinetic energy in the convective region of the Labrador Basin and along the West Greenland Current.

Forced migration and mental health: prolonged internal displacement, return migration and resilience.

Science.gov (United States)

Siriwardhana, Chesmal; Stewart, Robert

2013-03-01

Forced internal displacement has been rising steadily, mainly due to conflict. Many internally displaced people (IDP) experience prolonged displacement. Global research evidence suggests that many of these IDP are at high risk for developing mental disorders, adding weight to the global burden of disease. However, individual and community resilience may act as protective factors. Return migration may be an option for some IDP populations, especially when conflicts end, although return migration may itself be associated with worse mental health. Limited evidence is available on effects of resettlement or return migration following prolonged forced internal displacement on mental health. Also, the role of resilience factors remains to be clarified following situations of prolonged displacement. The public health impact of internal displacement is not clearly understood. Epidemiological and interventional research in IDP mental health needs to look beyond medicalised models and encompass broader social and cultural aspects. The resilience factor should be integrated and explored more in mental health research among IDP and a clearly focused multidisciplinary approach is advocated.

Investigation of Subcombination Internal Resonances in Cantilever Beams

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Haider N. Arafat

1998-01-01

Full Text Available Activation of subcombination internal resonances in transversely excited cantilever beams is investigated. The effect of geometric and inertia nonlinearities, which are cubic in the governing equation of motion, is considered. The method of time-averaged Lagrangian and virtual work is used to determine six nonlinear ordinary-differential equations governing the amplitudes and phases of the three interacting modes. Frequency- and force-response curves are generated for the case ω ≈ ω4 ≈ 1/2(ω2 + ω5. There are two possible responses: single-mode and three-mode responses. The single-mode periodic response is found to undergo supercritical and subcritical pitchfork bifurcations, which result in three-mode interactions. In the case of three-mode responses, there are conditions where the low-frequency mode dominates the response, resulting in high-amplitude quasiperiodic oscillations.

Comparative analysis of internal friction and natural frequency measured by free decay and forced vibration

International Nuclear Information System (INIS)

Wang, Y. Z.; Ding, X. D.; Xiong, X. M.; Zhang, J. X.

2007-01-01

Relations between various values of the internal friction (tgδ, Q -1 , Q -1* , and Λ/π) measured by free decay and forced vibration are analyzed systemically based on a fundamental mechanical model in this paper. Additionally, relations between various natural frequencies, such as vibration frequency of free decay ω FD , displacement-resonant frequency of forced vibration ω d , and velocity-resonant frequency of forced vibration ω 0 are calculated. Moreover, measurement of natural frequencies of a copper specimen of 99.9% purity has been made to demonstrate the relation between the measured natural frequencies of the system by forced vibration and free decay. These results are of importance for not only more accurate measurement of the elastic modulus of materials but also the data conversion between different internal friction measurements

Streamwise-body-force-model for rapid simulation combining internal and external flow fields

Directory of Open Access Journals (Sweden)

Cui Rong

2016-10-01

Full Text Available A streamwise-body-force-model (SBFM is developed and applied in the overall flow simulation for the distributed propulsion system, combining internal and external flow fields. In view of axial stage effects, fan or compressor effects could be simplified as body forces along the streamline. These body forces which are functions of local parameters could be added as source terms in Navier-Stokes equations to replace solid boundary conditions of blades and hubs. The validation of SBFM with uniform inlet and distortion inlet of compressors shows that pressure performance characteristics agree well with experimental data. A three-dimensional simulation of the integration configuration, via a blended wing body aircraft with a distributed propulsion system using the SBFM, has been completed. Lift coefficient and drag coefficient agree well with wind tunnel test results. Results show that to reach the goal of rapid integrated simulation combining internal and external flow fields, the computational fluid dynamics method based on SBFM is reasonable.

Thermal and Fluid Mechanical Investigation of an Internally Cooled Piston Rod

Science.gov (United States)

Klotsche, K.; Thomas, C.; Hesse, U.

2017-08-01

The Internal Cooling of Reciprocating Compressor Parts (ICRC) is a promising technology to reduce the temperature of the thermally stressed piston and piston rod of process gas compressors. The underlying heat transport is based on the flow of a two-phase cooling medium that is contained in the hollow reciprocating assembly. The reciprocating motion forces the phases to mix, enabling an enhanced heat transfer. In order to investigate this heat transfer, experimental results from a vertically reciprocating hollow rod are presented that show the influence of different liquid charges for different working temperatures. In addition, pressure sensors are used for a crank angle dependent analysis of the fluid mechanical processes inside the rod. The results serve to investigate the two-phase flow in terms of the velocity and distribution of the liquid and vapour phase for different liquid fractions.

The Interplay of Internal and Forced Modes of Hadley Cell Expansion: Lessons from the Global Warming Hiatus

Science.gov (United States)

Amaya, D. J.; Siler, N.; Xie, S. P.; Miller, A. J.

2017-12-01

The poleward branches of the Hadley Cells show a robust shift poleward shift during the satellite era, leading to concerns over the possible encroachment of the globe's subtropical dry zones into currently temperate climates. The extent to which this trend is caused by anthropogenic forcing versus internal variability remains the subject of considerable debate. In this study, we us a joint EOF method to identify two distinct modes of Hadley Cell variability: (i) an anthropogenically-forced mode, which we identify using a 20-member simulation of the historical climate, and (ii) an internal mode, which identify using a 1000-year pre-industrial control simulation with a global climate model. The forced mode is found to be closely related to the TOA radiative imbalance and exhibits a long-term trend since 1860, while the internal mode is found to be essentially indistinguishable from the El Niño Southern Oscillation (ENSO). Together these two modes explain an average of 70% of the interannual variability seen in model "edge indices" over the historical period. Since 1980, the superposition of forced and internal modes has resulted in a period of accelerated Hadley Cell expansion and decelerated global warming (i.e., the "hiatus"). A comparison of the change in these modes since 1980 indicates that by 2013 the signal has emerged above the noise of internal variability in the Southern Hemisphere (SH), but not in the Northern Hemisphere (NH), with the latter also exhibiting strong zonal asymmetry, particularly in the North Atlantic. Our results highlight the important interplay of internal and forced modes of Hadley Cell width change and improve our understanding of the interannual variability and long-term trend seen in observations.

Influence of Complete Coriolis Force on the Dispersion Relation of Ocean Internal-wave in a Background Currents Field

Directory of Open Access Journals (Sweden)

Liu Yongjun

2015-01-01

Full Text Available In this thesis, the influence of complete Coriolis force (the model includes both the vertical and horizontal components of Coriolis force on the dispersion relation of ocean internal-wave under background currents field are studied, it is important to the study of ocean internal waves in density-stratified ocean. We start from the control equation of sea water movement in the background of the non-traditional approximation, and the vertical velocity solution is derived where buoyancy frequency N(z gradually varies with the ocean depth z. The results show that the influence of complete Coriolis force on the dispersion relation of ocean internal-wave under background currents field is obvious, and these results provide strong evidence for the understanding of dynamic process of density stratified ocean internal waves.

Cross Cultural Awareness in International Military Operation: International Security Assistance Force in Afghanistan

Directory of Open Access Journals (Sweden)

Jowita Brudnicka

2015-12-01

Full Text Available Multiculturalism defined as a multitude of cultures can be typified as a major trend in international relations, what is a chellenge for every participant of global affairs. The phenomen of multiculturalism is absolutely nothing new, but under conditions of progresive globalisation mechanism its importance has been appreciated.In practise multinational forces have to operate in culturally heterogeneous environment in an array of tasks to combat threats of mostly a non-military transnational nature. All the time there are a highly complex relations within coalition personnel, in cuturally diverse society living in the theatre of operation and between all them mutually.

Force Concept Inventory-Based Multiple-Choice Test for Investigating Students' Representational Consistency

Science.gov (United States)

Nieminen, Pasi; Savinainen, Antti; Viiri, Jouni

2010-01-01

This study investigates students' ability to interpret multiple representations consistently (i.e., representational consistency) in the context of the force concept. For this purpose we developed the Representational Variant of the Force Concept Inventory (R-FCI), which makes use of nine items from the 1995 version of the Force Concept Inventory…

Legitimate Use of Military Force Against State-Sponsored International Terrorism

Science.gov (United States)

1989-07-01

principal. American international law professor and theorist Hans Kelsen writes, There are a number of ways in which force may be used indirectly by a...excluding anticipatory self-defense. Brownlie, Boyle, Jessup, Kelsen , Kunz, Sorensen, and Q. Wright, among others, assert that �there is no right of...law on self-defense. The most articulate writer in this regard is Hans Kelsen , who argues: All sides in this controversy over the scope of the

Analytical Investigation of Elastic Thin-Walled Cylinder and Truncated Cone Shell Intersection Under Internal Pressure

OpenAIRE

Zamani, J.; Soltani, B.; Aghaei, M.

2014-01-01

An elastic solution of cylinder-truncated cone shell intersection under internal pressure is presented. The edge solution theory that has been used in this study takes bending moments and shearing forces into account in the thin-walled shell of revolution element. The general solution of the cone equations is based on power series method. The effect of cone apex angle on the stress distribution in conical and cylindrical parts of structure is investigated. In addition, the effect of the inter...

Part-time careers in academic internal medicine: A report from the association of specialty professors part-time careers task force on behalf of the alliance for academic internal medicine

OpenAIRE

Linzer, M; Warde, C; Alexander, RW; DeMarco, DM; Haupt, A; Hicks, L; Kutner, J; Mangione, CM; Mechaber, H; Rentz, M; Riley, J; Schuster, B; Solomon, GD; Volberding, P; Ibrahim, T

2009-01-01

To establish guidelines for more effectively incorporating part-time faculty into departments of internal medicine, a task force was convened in early 2007 by the Association of Specialty Professors. The task force used informal surveys, current literature, and consensus building among members of the Alliance for Academic Internal Medicine to produce a consensus statement and a series of recommendations. The task force agreed that part-time faculty could enrich a department of medicine, enhan...

International study for an international career: a survey of the motivations and aspirations of international students in the UK

OpenAIRE

Packwood, Helen; Findlay, Allan; McCollum, David

2015-01-01

There are currently 435,000 international students studying in UK Universities. This paper investigates the forces driving student mobility and the relationship between student migration and future mobility plans. The research, based on a survey of over 3000 international students and interviews with senior staff in International Offices at ten UK Universities confirms the importance of understanding international student mobility as part of wider mobility trajectories.

Transitions to Peace: Effects on Internal Security Forces in Nicaragua, El Salvador and Guatemala

National Research Council Canada - National Science Library

Atha, Roberto J

2008-01-01

.... It reveals how the influence of the military affected the implementation of internal security reforms, influencing the professionalism and effectiveness of police forces in the fight against violence and gangs today...

A cross-case comparative analysis of international security forces' impacts on health systems in conflict-affected and fragile states.

Science.gov (United States)

Bourdeaux, Margaret; Kerry, Vanessa; Haggenmiller, Christian; Nickel, Karlheinz

2015-01-01

Destruction of health systems in fragile and conflict-affected states increases civilian mortality. Despite the size, scope, scale and political influence of international security forces intervening in fragile states, little attention has been paid to array of ways they may impact health systems beyond their effects on short-term humanitarian health aid delivery. Using case studies we published on international security forces' impacts on health systems in Haiti, Kosovo, Afghanistan and Libya, we conducted a comparative analysis that examined three questions: What aspects, or building blocks, of health systems did security forces impact across the cases and what was the nature of these impacts? What forums or mechanisms did international security forces use to interact with health system actors? What policies facilitated or hindered security forces from supporting health systems? We found international security forces impacted health system governance, information systems and indigenous health delivery organizations. Positive impacts included bolstering the authority, transparency and capability of health system leadership. Negative impacts included undermining the impartial nature of indigenous health institutions by using health projects to achieve security objectives. Interactions between security and health actors were primarily ad hoc, often to the detriment of health system support efforts. When international security forces were engaged in health system support activities, the most helpful communication and consultative mechanisms to manage their involvement were ones that could address a wide array of problems, were nimble enough to accommodate rapidly changing circumstances, leveraged the power of personal relationships, and were able to address the tensions that arose between security and health system supporting strategies. Policy barriers to international security organizations participating in health system support included lack of mandate, conflicts

Measurement of internal forces in superconducting accelerator magnets with strain gauge transducers

International Nuclear Information System (INIS)

Goodzeit, C.L.; Anerella, M.D.; Ganetis, G.L.

1988-01-01

An improved method has been developed for the measurement of internal forces in superconducting accelerator magnets, in particular the compressive stresses in coils and the end restraint forces on the coils. The transducers have been designed to provide improved sensitivity to purely mechanical strain by using bending mode deflections for sensing the applied loads. Strain gauge resistance measurements are made with a new system that eliminates sources of errors due to spurious resistance changes in interconnecting wiring and solder joints. The design of the transducers and their measurement system is presented along with a discussion of the method of compensation for thermal and magnetic effects, methods of calibration with typical calibration data, and measured effect in actual magnets of the thermal stress changes from cooldown and the Lorentz forces during magnet excitation. 13 figs., 1 tab

Investigations on pneumatically forced-actuated compressor valves

Science.gov (United States)

Stöckel, Christian; Thomas, Christiane; Nickl, Jörg; Hesse, Ullrich

2017-08-01

In the present paper the performance of a novel designed valve for reciprocating piston machines is investigated, which makes existing compressors utilizable for operating as expander. Three design parameters were identified as critical for the valves performance particularly in forced actuated mode. Within a numerical simulation a study on the crucial geometrical parameters, the influence could be observed. Afterwards the experimental setup for the integral test of the valve design is presented and also additional tests for single valve components.

International veterinary epilepsy task force consensus proposal : diagnostic approach to epilepsy in dogs

NARCIS (Netherlands)

De Risio, Luisa; Bhatti, Sofie; Muñana, Karen; Penderis, Jacques; Stein, Veronika; Tipold, Andrea; Berendt, Mette; Farqhuar, Robyn; Fischer, Andrea; Long, Sam; Mandigers, Paul J J; Matiasek, Kaspar; Packer, Rowena M A; Pakozdy, Akos; Patterson, Ned; Platt, Simon; Podell, Michael; Potschka, Heidrun; Batlle, Martí Pumarola; Rusbridge, Clare; Volk, Holger A

2015-01-01

This article outlines the consensus proposal on diagnosis of epilepsy in dogs by the International Veterinary Epilepsy Task Force. The aim of this consensus proposal is to improve consistency in the diagnosis of epilepsy in the clinical and research settings. The diagnostic approach to the patient

Internal Barriers to Implementing Diversity Management in the Air Force: Four Conversations We Must Have

National Research Council Canada - National Science Library

Bean, Debra

2000-01-01

.... This project examined one part of internal environmental analysis, the likely barriers to implementing diversity, to provide Air Force planners a set of considerations for effective program development...

Atomic force microscopy as a tool for the investigation of living cells.

Science.gov (United States)

Morkvėnaitė-Vilkončienė, Inga; Ramanavičienė, Almira; Ramanavičius, Arūnas

2013-01-01

Atomic force microscopy is a valuable and useful tool for the imaging and investigation of living cells in their natural environment at high resolution. Procedures applied to living cell preparation before measurements should be adapted individually for different kinds of cells and for the desired measurement technique. Different ways of cell immobilization, such as chemical fixation on the surface, entrapment in the pores of a membrane, or growing them directly on glass cover slips or on plastic substrates, result in the distortion or appearance of artifacts in atomic force microscopy images. Cell fixation allows the multiple use of samples and storage for a prolonged period; it also increases the resolution of imaging. Different atomic force microscopy modes are used for the imaging and analysis of living cells. The contact mode is the best for cell imaging because of high resolution, but it is usually based on the following: (i) image formation at low interaction force, (ii) low scanning speed, and (iii) usage of "soft," low resolution cantilevers. The tapping mode allows a cell to behave like a very solid material, and destructive shear forces are minimized, but imaging in liquid is difficult. The force spectroscopy mode is used for measuring the mechanical properties of cells; however, obtained results strongly depend on the cell fixation method. In this paper, the application of 3 atomic force microscopy modes including (i) contact, (ii) tapping, and (iii) force spectroscopy for the investigation of cells is described. The possibilities of cell preparation for the measurements, imaging, and determination of mechanical properties of cells are provided. The applicability of atomic force microscopy to diagnostics and other biomedical purposes is discussed.

The impact of international shipping on European air quality and climate forcing

Energy Technology Data Exchange (ETDEWEB)

van Aardenne, J. [European Environment Agency (EEA), Copenhagen (Denmark); Colette, A. [INERIS (France); Degraeuwe, B.; de Vlieger, I. [VITO (Belgium); Hammingh, P. [PBL Netherlands Environmental Assessment Agency (Netherlands); Viana, M. [CSIC (Spain)

2013-03-15

This EEA Technical report provides an overview on the state of knowledge on the impact of international shipping in European waters to air quality and climate change. Based on literature review and model assessment studies information is provided on past and future emissions of air pollutants and greenhouse gases, monitoring of ship emissions, emission mitigation policies and impact on European air quality and radiative forcing. (Author)

Analytical Investigation of Elastic Thin-Walled Cylinder and Truncated Cone Shell Intersection Under Internal Pressure.

Science.gov (United States)

Zamani, J; Soltani, B; Aghaei, M

2014-10-01

An elastic solution of cylinder-truncated cone shell intersection under internal pressure is presented. The edge solution theory that has been used in this study takes bending moments and shearing forces into account in the thin-walled shell of revolution element. The general solution of the cone equations is based on power series method. The effect of cone apex angle on the stress distribution in conical and cylindrical parts of structure is investigated. In addition, the effect of the intersection and boundary locations on the circumferential and longitudinal stresses is evaluated and it is shown that how quantitatively they are essential.

Investigation of a mutual interaction force at different pressure amplitudes in sulfuric acid

International Nuclear Information System (INIS)

Rezaee, Nastaran; Sadighi-Bonabi, Rasoul; Mirheydari, Mona; Ebrahimi, Homa

2011-01-01

This paper investigates the secondary Bjerknes force for two oscillating bubbles in various pressure amplitudes in a concentration of 95% sulfuric acid. The equilibrium radii of the bubbles are assumed to be smaller than 10 μm at a frequency of 37 kHz in various strong driving acoustical fields around 2.0 bars (1 bar=10 5 Pa). The secondary Bjerknes force is investigated in uncoupled and coupled states between the bubbles, with regard to the quasi-adiabatic model for the bubble interior. It finds that the value of the secondary Bjerknes force depends on the driven pressure of sulfuric acid and its amount would be increased by liquid pressure amplitude enhancement. The results show that the repulsion area of the interaction force would be increased by increasing the driven pressure because of nonlinear oscillation of bubbles. (condensed matter: electronic structure, electrical, magnetic, and optical properties)

Investigation of the nucleon-nucleon tensor force in three-nucleon system

Energy Technology Data Exchange (ETDEWEB)

Clajus, M.; Egun, P.M.; Gruebler, W.; Hautle, P. (Eidgenoessische Technische Hochschule, Zurich (Switzerland). Inst. fuer Mittelenergiephysik); Slaus, I. (Institut Rudjer Boskovic, Zagreb (Yugoslavia)); Vuaridel, B. (Michigan Univ., Ann Arbor (USA) Brookhaven National Lab., Upton, NY (USA)); Sperisen, F. (Indiana Univ., Bloomington (USA). Cyclotron Facility); Kretschmer, W.; Rauscher, A.; Schuster, W.; Weidmann, R.; Haller, M. (Erlangen-Nuernberg Univ., Erlangen (Germany, F.R.)); Bruno, M.; Cannata, F.; D' Agostino, M. (Istituto Nazionale di Fisica Nucleare, Bologna (Italy)); Witala, H.; Cornelius, T.; Gloeckle, W. (Bochum Univ. (Germany, F.R.)); Schmelzbach, P.A. (Paul Scherrer Inst., Villigen (Switzerland))

1990-08-16

Proton-deuteron elastic scattering has been investigated at E{sub p}=22.7 MeV by comparison of rigorous Faddeev calculations with experimental results. The observable most sensitive to the tensor force is the nucleon-nucleon polarization transfer coefficient K{sub y}sup(y'). The new angular distribution of K{sub y}sup(y') clearly favours the tensor force of the Bonn A potential, which is weaker than the one of the Paris potential. (orig.).

Predicting wind farm wake interaction with RANS: an investigation of the Coriolis force

DEFF Research Database (Denmark)

van der Laan, Paul; Hansen, Kurt Schaldemose; Sørensen, Niels N.

2015-01-01

A Reynolds-averaged Navier-Stokes code is used to simulate the interaction of two neighboring wind farms. The influence of the Coriolis force is investigated by modeling the atmospheric surface/boundary layer with three different methodologies. The results show that the Coriolis force is negligible...

Source evaluation report phase 2 investigation: Limited field investigation. Final report: United States Air Force Environmental Restoration Program, Eielson Air Force Base, Alaska

Energy Technology Data Exchange (ETDEWEB)

1994-10-01

This report describes the limited field investigation work done to address issues and answer unresolved questions regarding a collection of potential contaminant sources at Eielson Air Force Base (AFB), near Fairbanks, Alaska. These sources were listed in the Eielson AFB Federal Facility Agreement supporting the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) cleanup of the base. The limited field investigation began in 1993 to resolve all remaining technical issues and provide the data and analysis required to evaluate the environmental hazard associated with these sites. The objective of the limited field investigation was to allow the remedial project managers to sort each site into one of three categories: requiring remedial investigation/feasibility study, requiring interim removal action, or requiring no further remedial action.

Internal development of vegetative buds of Norway spruce trees in relation to accumulated chilling and forcing temperatures.

Science.gov (United States)

Viherä-Aarnio, Anneli; Sutinen, Sirkka; Partanen, Jouni; Häkkinen, Risto

2014-05-01

The timing of budburst of temperate trees is known to be controlled by complicated interactions of temperature and photoperiod. To improve the phenological models of budburst, better knowledge of the internal bud development preceding budburst in relation to environmental cues is needed. We studied the effect of accumulated chilling and forcing temperatures on the internal development of vegetative buds preceding budburst in Norway spruce [Picea abies (L.) Karst.]. Branches from 17-year-old trees of southern Finnish origin were transferred eight times at 1- to 2-week intervals from October to December 2007 from the field at Punkaharju (61°48'N, 29°20'E) to the greenhouse with forcing conditions (day length 12 h, +20 °C). After seven different durations of forcing, the developmental phase and primordial shoot growth of the buds were analysed at the stereomicroscopic level. Air temperature was recorded hourly throughout the study period. The accumulated chilling unit sum had a significant effect on the temperature sum that was required to attain a certain developmental phase; a higher amount of chilling required a lower amount of forcing. The variation in the rate of development of different buds within each sample branch in relation to the chilling unit and forcing temperature sum was low. Regarding primordial shoot growth, there was also an inverse relation between accumulated chilling and forcing, i.e., a higher accumulated chilling unit sum before forcing required a lower temperature sum to initiate primordial shoot growth and resulted in a stronger effect of accumulated forcing. A second-order regression model with an interaction of chilling and forcing explained the variation of primordial shoot growth with high precision (R(2) = 0.88). However, further studies are required to determine the final parameter values to be used in phenological modelling. © The Author 2014. Published by Oxford University Press. All rights reserved.

Investigating bioconjugation by atomic force microscopy

Science.gov (United States)

2013-01-01

Nanotechnological applications increasingly exploit the selectivity and processivity of biological molecules. Integration of biomolecules such as proteins or DNA into nano-systems typically requires their conjugation to surfaces, for example of carbon-nanotubes or fluorescent quantum dots. The bioconjugated nanostructures exploit the unique strengths of both their biological and nanoparticle components and are used in diverse, future oriented research areas ranging from nanoelectronics to biosensing and nanomedicine. Atomic force microscopy imaging provides valuable, direct insight for the evaluation of different conjugation approaches at the level of the individual molecules. Recent technical advances have enabled high speed imaging by AFM supporting time resolutions sufficient to follow conformational changes of intricately assembled nanostructures in solution. In addition, integration of AFM with different spectroscopic and imaging approaches provides an enhanced level of information on the investigated sample. Furthermore, the AFM itself can serve as an active tool for the assembly of nanostructures based on bioconjugation. AFM is hence a major workhorse in nanotechnology; it is a powerful tool for the structural investigation of bioconjugation and bioconjugation-induced effects as well as the simultaneous active assembly and analysis of bioconjugation-based nanostructures. PMID:23855448

Project Portfolio Management: An Investigation of One Air Force Product Center

National Research Council Canada - National Science Library

Edmunds, Bryan D

2005-01-01

.... This research focuses on the portfolio management (project selection and resource allocation) part of the CTRRP. The purpose of this research effort was to investigate the use of portfolio management within the Air Force...

A clinical investigation of force delivery systems for orthodontic space closure.

Science.gov (United States)

Nightingale, C; Jones, S P

2003-09-01

To investigate the force retention, and rates of space closure achieved by elastomeric chain and nickel titanium coil springs. Randomized clinical trial. Eastman Dental Hospital, London and Queen Mary's University Hospital, Roehampton, 1998-2000. Twenty-two orthodontic patients, wearing the pre-adjusted edgewise appliance undergoing space closure in opposing quadrants, using sliding mechanics on 0.019 x 0.025-inch posted stainless steel archwires. Medium-spaced elastomeric chain [Durachain, OrthoCare (UK) Ltd., Bradford, UK] and 9-mm nickel titanium coil springs [OrthoCare (UK) Ltd.] were placed in opposing quadrants for 15 patients. Elastomeric chain only was used in a further seven patients. The initial forces on placement and residual forces at the subsequent visit were measured with a dial push-pull gauge [Orthocare (UK) Ltd]. Study models of eight patients were taken before and after space closure, from which measurements were made to establish mean space closure. The forces were measured in grammes and space closure in millimetres. Fifty-nine per cent (31/53) of the elastomeric sample maintained at least 50 per cent of the initial force over a time period of 1-15 weeks. No sample lost all its force, and the mean loss was 47 per cent (range: 0-76 per cent). Nickel titanium coil springs lost force rapidly over 6 weeks, following that force levels plateaued. Forty-six per cent (12/26) maintained at least 50 per cent of their initial force over a time period of 1-22 weeks, and mean force loss was 48 per cent (range: 12-68 per cent). The rate of mean weekly space closure for elastomeric chain was 0.21 mm and for nickel titanium coil springs 0.26 mm. There was no relationship between the initial force applied and rate of space closure. None of the sample failed during the study period giving a 100 per cent response rate. In clinical use, the force retention of elastomeric chain was better than previously concluded. High initial forces resulted in high force decay

International Business Cycle

OpenAIRE

Marek Lubiński

2007-01-01

Prime stylized facts of international business cycle theory refer to positive correlation in the cyclical components of important macroeconomic variables across countries. However a number of indicators of business cycle synchronization do not point to clear trends. It can be ascribed to the fact that different forces influence level of business cycle correlation. When investigating into the forces behind the commonness in aggregate fluctuations economic research seems to have pointed in two ...

Forced harmonic oscillations of the Euler-Bernoulli beam with resistance forces

Directory of Open Access Journals (Sweden)

Yuriy S. Krutiy

2015-12-01

Full Text Available The important issue in the oscillation theory is the study of resistance impact on oscillatory processes. Unlike the calculations of free oscillations, that reside in determination of natural frequencies and waveshapes and unlike the calculations of forced oscillations far away from resonance, that are performing without reference to friction, the oscillations researches in vicinity of resonance need accounting of friction forces. Special attention is paid to forced transverse fluctuations in beams as an important technical problem for engineering and building. Aim: The aim of the work is constructing of analytical solution of the problem of forced transverse vibrations of a straight rod with constant cross-section, which is under the influence of the harmonic load taking into account external and internal resistances. Materials and Methods: The internal resistance is taken into account using the corrected hypothesis of Kelvin-Voigt which reflects the empirically proven fact about the frequency-independent internal friction in the material. The external friction is also considered as frequency-independent. Results: An analytical solution is built for the differential equation of forced transverse oscillations of a straight rod with constant cross-section which is under the influence of the harmonic load taking into account external and internal resistances. As a result, analytically derived formulae are presented which describe the forced dynamic oscillations and the dynamic internal forces due to the harmonic load applied to the rod thus reducing the problem with any possible fixed ends to the search of unknown integration constants represented in a form of initial parameters.

International Society for Bipolar Disorders Task Force on Suicide

DEFF Research Database (Denmark)

Schaffer, Ayal; Isometsä, Erkki T; Tondo, Leonardo

2015-01-01

significantly associated with suicide attempts were: female gender, younger age at illness onset, depressive polarity of first illness episode, depressive polarity of current or most recent episode, comorbid anxiety disorder, any comorbid substance use disorder, alcohol use disorder, any illicit substance use......OBJECTIVES: Bipolar disorder is associated with a high risk of suicide attempts and suicide death. The main objective of the present study was to identify and quantify the demographic and clinical correlates of attempted and completed suicide in people with bipolar disorder. METHODS: Within...... the framework of the International Society for Bipolar Disorders Task Force on Suicide, a systematic review of articles published since 1980, characterized by the key terms bipolar disorder and 'suicide attempts' or 'suicide', was conducted, and data extracted for analysis from all eligible articles...

[Stigma and Mental Health in Victims of Colombia's Internal Armed Conflict in Situation of Forced Displacement].

Science.gov (United States)

Campo-Arias, Adalberto; Herazo, Edwin

2014-01-01

The prolonged sociopolitical phenomenon of Colombian violence generated a high number of victims, many of whom suffered a continual process of internal displacement and stigma-discrimination complex. To postulate possible mechanisms by which victims of Colombia's internal armed conflict in a situation of forced displacement were stigmatized and discriminated. Stigma affects mental health, not only because it represents a major stressor for discriminated individuals and groups, but also because it accounts for inequalities and inequities in health. Initially, as the victims of the internal armed conflict in situation of forced displacement were not considered as such, but as responsible for the situation. Thus, they had to cope with the social and economic inequalities, explained partially by low categorization or status that they received, possibly due to poor construction of social capital in the country. Also, victims of the internal armed conflict suffer from intersectional stigma and discrimination due to other characteristics such as gender, sexual orientation, ethnic-racial origin, or meeting criteria for a mental disorder. An active process of inclusive social development is required for the displaced victims of the armed conflict,in order to reduce multiple stigma and ensure their mental health. Copyright © 2014 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

Investigations on the Effects of Vortex-Induced Vibration with Different Distributions of Lorentz Forces

Directory of Open Access Journals (Sweden)

Hui Zhang

2017-01-01

Full Text Available The control of vortex-induced vibration (VIV in shear flow with different distributions of Lorentz force is numerically investigated based on the stream function–vorticity equations in the exponential-polar coordinates exerted on moving cylinder for Re = 150. The cylinder motion equation coupled with the fluid, including the mathematical expressions of the lift force coefficient C l , is derived. The initial and boundary conditions as well as the hydrodynamic forces on the surface of cylinder are also formulated. The Lorentz force applied to suppress the VIV has no relationship with the flow field, and involves two categories, i.e., the field Lorentz force and the wall Lorentz force. With the application of symmetrical Lorentz forces, the symmetric field Lorentz force can amplify the drag, suppress the flow separation, decrease the lift fluctuation, and then suppress the VIV while the wall Lorentz force decreases the drag only. With the application of asymmetrical Lorentz forces, besides the above-mentioned effects, the field Lorentz force can increase additional lift induced by shear flow, whereas the wall Lorentz force can counteract the additional lift, which is dominated on the total effect.

International confederation for cleft lip and palate and related craniofacial anomalies task force report: holistic outcomes.

Science.gov (United States)

Broder, Hillary L

2014-11-01

Objective : This paper describes the process and outcomes of the 2013 American Cleft Palate-Craniofacial Association task force on Holistic Outcomes. The goals and membership of the task force are presented. Methods : Using internet communication, the group introduced themselves, shared ideas and information related to holistic assessment and implementation of using a validated holistic measure, the Child Oral Health Impact Profile (COHIP) at participating international sites. Results : Data from the sites were analyzed using descriptive statistics. Administration of the COHIP was successful. It varied from self-completion as well as verbal presentation due to language differences and a function of the short time period to complete collection. Additionally qualitative comments were reported by the task force site directors. Conclusions : Future directions for holistic assessment and communication among task force members and sites were discussed at the Congress and are presented in this report.

Report by the International Space Station (ISS) Management and Cost Evaluation (IMCE) Task Force

Science.gov (United States)

Young, A. Thomas; Kellogg, Yvonne (Technical Monitor)

2001-01-01

The International Space Station (ISS) Management and Cost Evaluation Task Force (IMCE) was chartered to conduct an independent external review and assessment of the ISS cost, budget, and management. In addition, the Task Force was asked to provide recommendations that could provide maximum benefit to the U.S. taxpayers and the International Partners within the President's budget request. The Task Force has made the following principal findings: (1) The ISS Program's technical achievements to date, as represented by on-orbit capability, are extraordinary; (2) The Existing ISS Program Plan for executing the FY 02-06 budget is not credible; (3) The existing deficiencies in management structure, institutional culture, cost estimating, and program control must be acknowledged and corrected for the Program to move forward in a credible fashion; (4) Additional budget flexibility, from within the Office of Space Flight (OSF) must be provided for a credible core complete program; (5) The research support program is proceeding assuming the budget that was in place before the FY02 budget runout reduction of $1B; (6) There are opportunities to maximize research on the core station program with modest cost impact; (7) The U.S. Core Complete configuration (three person crew) as an end-state will not achieve the unique research potential of the ISS; (8) The cost estimates for the U.S.-funded enhancement options (e.g., permanent seven person crew) are not sufficiently developed to assess credibility. After these findings, the Task Force has formulated several primary recommendations which are published here and include: (1) Major changes must be made in how the ISS program is managed; (2) Additional cost reductions are required within the baseline program; (3) Additional funds must be identified and applied from the Human Space Flight budget; (4) A clearly defined program with a credible end-state, agreed to by all stakeholders, must be developed and implemented.

Polyphilic Interactions as Structural Driving Force Investigated by Molecular Dynamics Simulation (Project 7

Directory of Open Access Journals (Sweden)

Christopher Peschel

2017-09-01

Full Text Available We investigated the effect of fluorinated molecules on dipalmitoylphosphatidylcholine (DPPC bilayers by force-field molecular dynamics simulations. In the first step, we developed all-atom force-field parameters for additive molecules in membranes to enable an accurate description of those systems. On the basis of this force field, we performed extensive simulations of various bilayer systems containing different additives. The additive molecules were chosen to be of different size and shape, and they included small molecules such as perfluorinated alcohols, but also more complex molecules. From these simulations, we investigated the structural and dynamic effects of the additives on the membrane properties, as well as the behavior of the additive molecules themselves. Our results are in good agreement with other theoretical and experimental studies, and they contribute to a microscopic understanding of interactions, which might be used to specifically tune membrane properties by additives in the future.

Contribution of Leg-Muscle Forces to Paddle Force and Kayak Speed During Maximal-Effort Flat-Water Paddling.

Science.gov (United States)

Nilsson, Johnny E; Rosdahl, Hans G

2016-01-01

The purpose was to investigate the contribution of leg-muscle-generated forces to paddle force and kayak speed during maximal-effort flat-water paddling. Five elite male kayakers at national and international level participated. The participants warmed up at progressively increasing speeds and then performed a maximal-effort, nonrestricted paddling sequence. This was followed after 5 min rest by a maximal-effort paddling sequence with the leg action restricted--the knee joints "locked." Left- and right-side foot-bar and paddle forces were recorded with specially designed force devices. In addition, knee angular displacement of the right and left knees was recorded with electrogoniometric technique, and the kayak speed was calculated from GPS signals sampled at 5 Hz. The results showed that reduction in both push and pull foot-bar forces resulted in a reduction of 21% and 16% in mean paddle-stroke force and mean kayak speed, respectively. Thus, the contribution of foot-bar force from lower-limb action significantly contributes to kayakers' paddling performance.

Multifarious applications of atomic force microscopy in forensic science investigations.

Science.gov (United States)

Pandey, Gaurav; Tharmavaram, Maithri; Rawtani, Deepak; Kumar, Sumit; Agrawal, Y

2017-04-01

Forensic science is a wide field comprising of several subspecialties and uses methods derived from natural sciences for finding criminals and other evidence valid in a legal court. A relatively new area; Nano-forensics brings a new era of investigation in forensic science in which instantaneous results can be produced that determine various agents such as explosive gasses, biological agents and residues in different crime scenes and terrorist activity investigations. This can be achieved by applying Nanotechnology and its associated characterization techniques in forensic sciences. Several characterization techniques exist in Nanotechnology and nano-analysis is one such technique that is used in forensic science which includes Electron microscopes (EM) like Transmission (TEM) and Scanning (SEM), Raman microscopy (Micro -Raman) and Scanning Probe Microscopes (SPMs) like Atomic Force Microscope (AFM). Atomic force microscopy enables surface characterization of different materials by examining their morphology and mechanical properties. Materials that are immeasurable such as hair, body fluids, textile fibers, documents, polymers, pressure sensitive adhesives (PSAs), etc. are often encountered during forensic investigations. This review article will mainly focus on the use of AFM in the examination of different evidence such as blood stains, forged documents, human hair samples, ammunitions, explosives, and other such applications in the field of Forensic Science. Copyright © 2017 Elsevier B.V. All rights reserved.

Investigating the relationship between pressure force and acoustic waveform in footstep sounds

DEFF Research Database (Denmark)

Grani, Francesco; Serafin, Stefania; Götzen, Amalia De

2013-01-01

In this paper we present an inquiry into of the relationships between audio waveforms and ground reaction force in recorded footstep sounds. In an anechoic room, we recorded several footstep sounds produced while walking on creaking wood and gravel. The recordings were performed by using a pair o...... of sandals embedded with six pressure sensors each. Investigations of the relationships between recorded force and footstep sounds is presented, together with several possible applications of the system.......In this paper we present an inquiry into of the relationships between audio waveforms and ground reaction force in recorded footstep sounds. In an anechoic room, we recorded several footstep sounds produced while walking on creaking wood and gravel. The recordings were performed by using a pair...

Operable Unit 1 remedial investigation report, Eielson Air Force Base, Alaska

International Nuclear Information System (INIS)

Gilmore, T.J.; Fruland, R.M.; Liikala, T.L.

1994-06-01

This remedial investigation report for operable Unit 1 (OU-1) at Eielson Air Force Base presents data, calculations, and conclusions as to the nature and extent of surface and subsurface contamination at the eight source areas that make up OU-1. The information is based on the 1993 field investigation result and previous investigations. This report is the first in a set of three for OU-1. The other reports are the baseline risk assessment and feasibility study. The information in these reports will lead to a Record of Decision that will guide and conclude the environmental restoration effort for OU-1 at Eielson Air Force Base. The primary contaminants of concern include fuels and fuel-related contaminants (diesel; benzene, toluene, ethylbenzene, and xylene; total petroleum hydrocarbon; polycyclic aromatic hydrocarbons), maintenance-related solvents and cleaners (volatile chlorinated hydrocarbons such as trichloroothylene), polychlorinated biphenyls, and dichlorodiphenyltrichloroethane (DDT). The origins of contaminants of concern include leaks from storage tanks, drums and piping, and spills. Ongoing operations and past sitewide practices also contribute to contaminants of concern at OU-1 source areas. These include spraying mixed oil and solvent wastes on unpaved roads and aerial spraying of DDT

Theoretical and Experimental Investigation of Force Estimation Errors Using Active Magnetic Bearings with Embedded Hall Sensors

DEFF Research Database (Denmark)

Voigt, Andreas Jauernik; Santos, Ilmar

2012-01-01

to ∼ 20% of the nominal air gap the force estimation error is found to be reduced by the linearized force equation as compared to the quadratic force equation, which is supported by experimental results. Additionally the FE model is employed in a comparative study of the force estimation error behavior...... of AMBs by embedding Hall sensors instead of mounting these directly on the pole surfaces, force estimation errors are investigated both numerically and experimentally. A linearized version of the conventionally applied quadratic correspondence between measured Hall voltage and applied AMB force...

Self-determination in New Contexts: The Self-determination of Refugees and Forced Migrants in International Law

Directory of Open Access Journals (Sweden)

Kathleen McVay

2012-06-01

Full Text Available The international movement of people as a result of conflict, natural disaster, and famine is increasingly challenging for States. The Refugee Convention and its additional protocols have proven to be inadequate for protecting many people from human rights abuses. Accordingly this paper seeks to ascertain whether self-determination may operate to protect permanent refugee and forced migrant communities. Self-determination is a human right that has attracted considerable controversy. However, its universal applicability and the strength of the right make it an attractive means of limiting the power of a State in respect of refugee and forced migrant communities. Drawing from historical analogy this article concludes that in limited circumstances self-determination may be available for permanent refugee or forced migrant communities.

Evolution of strategies and competition in the international airline industry: a practical analysis using porter's competitive forces model

OpenAIRE

Zannoni, Niccolò

2013-01-01

This master thesis describes the evolution of the competition and strategies in the international airline industry. It studies the industry before and after deregulation, using the competitive forces model.

The Role of the United Nations in the 21st Century: A Case for an International Police Force

National Research Council Canada - National Science Library

Kersten, Jeffrey

2002-01-01

... its traditional logic and employment of military forces for international peacekeeping operations, The benefits of global economic investment and individual liberties should be apparent to all as a positive outcome...

Internalization of Air Force Core Values Among Company Grade Officers: Where are We and Where are We Going?

National Research Council Canada - National Science Library

Anderson, Brian

1997-01-01

Our senior leadership is placing renewed emphasis on Air Force core values and recognizes the internalization of these values are critical to the long-term success of our professional officer corps...

Dynamic force profile in hydraulic hybrid vehicles: a numerical investigation

Science.gov (United States)

Mohaghegh-Motlagh, Amin; Elahinia, Mohammad H.

2010-04-01

A hybrid hydraulic vehicle (HHV) combines a hydraulic sub-system with the conventional drivetrain in order to improve fuel economy for heavy vehicles. The added hydraulic module manages the storage and release of fluid power necessary to assist the motion of the vehicle. The power collected by a pump/motor (P/M) from the regenerative braking phase is stored in a high-pressure accumulator and then released by the P/M to the driveshaft during the acceleration phase. This technology is effective in significantly improving fuel-economy for heavy-class vehicles with frequent stop-and-go drive schedules. Despite improved fuel economy and higher vehicle acceleration, noise and vibrations are one of the main problems of these vehicles. The dual function P/Ms are the main source of noise and vibration in a HHV. This study investigates the dynamics of a P/M and particularly the profile and frequency-dependence of the dynamic forces generated by a bent-axis P/M unit. To this end, the fluid dynamics side of the problem has been simplified for investigating the system from a dynamics perspective. A mathematical model of a bent axis P/M has been developed to investigate the cause of vibration and noise in HHVs. The forces are calculated in time and frequency domains. The results of this work can be used to study the vibration response of the chassis and to design effective vibration isolation systems for HHVs.

Classical description of dynamical many-body systems with central forces, spin-orbit forces and spin-spin forces

International Nuclear Information System (INIS)

Goepfert, A.

1994-01-01

This thesis develops a new model, and related numerical methods, to describe classical time-dependent many-body systems interacting through central forces, spin-orbit forces and spin-spin forces. The model is based on two-particle interactions. The two-body forces consist of attractive and repulsive parts. In this model the investigated multi-particle systems are self-bound. Also the total potential of the whole ensemble is derived from the two-particle potential and is not imposed 'from outside'. Each particle has the three degrees of freedom of its centre-of-mass motion and the spin degree of freedom. The model allows for the particles to be either charged or uncharged. Furthermore, each particle has an angular momentum, an intrinsic spin, and a magnetic dipole moment. Through the electromagnetic forces between these charges and moments there arise dynamical couplings between them. The internal interactions between the charges and moments are well described by electromagnetic coupling mechanisms. In fact, compared to conventional classical molecular dynamics calculations in van der Waals clusters, which have no spin degrees of freedom, or for Heisenberg spin Systems, which have no orbital degrees of freedom, the model presented here contains both types of degrees of freedom with a highly non-trivial coupling. The model allows to study the fundamental effects resulting from the dynamical coupling of the spin and the orbital-motion sub-systems. In particular, the dynamics of the particle mass points show a behaviour basically different from the one of particles in a potential with only central forces. Furthermore, a special type of quenching procedure was invented, which tends to drive the multi-particle Systems into states with highly periodic, non-ergodic behaviour. Application of the model to cluster simulations has provided evidence that the model can also be used to investigate items like solid-to-liquid phase transitions (melting), isomerism and specific heat

Internal and external North Atlantic Sector variability in the Kiel climate model

Energy Technology Data Exchange (ETDEWEB)

Latif, Mojib; Park, Wonsun; Ding, Hui; Keenlyside, Noel S. [Leibniz-Inst. fuer Meereswissenschaften, Kiel (Germany)

2009-08-15

The internal and external North Atlantic Sector variability is investigated by means of a multimillennial control run and forced experiments with the Kiel Climate Model (KCM). The internal variability is studied by analyzing the control run. The externally forced variability is investigated in a run with periodic millennial solar forcing and in greenhouse warming experiments with enhanced carbon dioxide concentrations. The surface air temperature (SAT) averaged over the Northern Hemisphere simulated in the control run displays enhanced variability relative to the red background at decadal, centennial, and millennial timescales. Special emphasis is given to the variability of the Meridional Overturning Circulation (MOC). The MOC plays an important role in the generation of internal climate modes. Furthermore, the MOC provides a strong negative feedback on the Northern Hemisphere SAT in both the solar and greenhouse warming experiments, thereby moderating the direct effects of the external forcing in the North Atlantic. The implications of the results for decadal predictability are discussed. (orig.)

Topography and Mechanical Property Mapping of International Simple Glass Surfaces with Atomic Force Microscopy

Energy Technology Data Exchange (ETDEWEB)

Pierce, Eric M [ORNL

2014-01-01

Quantitative Nanomechanical Peak Force (PF-QNM) TappingModeTM atomic force microscopy measurements are presented for the first time on polished glass surfaces. The PF-QNM technique allows for topography and mechanical property information to be measured simultaneously at each pixel. Results for the international simple glass which represents a simplified version of SON68 glass suggests an average Young s modulus of 78.8 15.1 GPa is within the experimental error of the modulus measured for SON68 glass (83.6 2 GPa) with conventional approaches. Application of the PF-QNM technique will be extended to in situ glass corrosion experiments with the goal of gaining atomic-scale insights into altered layer development by exploiting the mechanical property differences that exist between silica gel (e.g., altered layer) and pristine glass surface.

Investigation of internally finned LED heat sinks

Science.gov (United States)

Li, Bin; Xiong, Lun; Lai, Chuan; Tang, Yumei

2018-03-01

A novel heat sink is proposed, which is composed of a perforated cylinder and internally arranged fins. Numerical studies are performed on the natural convection heat transfer from internally finned heat sinks; experimental studies are carried out to validate the numerical results. To compare the thermal performances of internally finned heat sinks and externally finned heat sinks, the effects of the overall diameter, overall height, and installation direction on maximum temperature, air flow and heat transfer coefficient are investigated. The results demonstrate that internally finned heat sinks show better thermal performance than externally finned heat sinks; the maximum temperature of internally finned heat sinks decreases by up to 20% compared with the externally finned heat sinks. The existence of a perforated cylinder and the installation direction of the heat sink affect the thermal performance significantly; it is shown that the heat transfer coefficient of the heat sink with the perforated cylinder is improved greater than that with the imperforated cylinder by up to 34%, while reducing the mass of the heat sink by up to 13%. Project supported by the Scientific Research Fund of Sichuan Provincial Education Department (No. 18ZB0516) and the Sichuan University of Arts and Science (No. 2016KZ009Y).

Relative influences of the metocean forcings on the drifting ice pack and estimation of internal ice stress gradients in the Labrador Sea

Science.gov (United States)

Turnbull, I. D.; Torbati, R. Z.; Taylor, R. S.

2017-07-01

Understanding the relative influences of the metocean forcings on the drift of sea ice floes is a crucial component to the overall characterization of an ice environment and to developing an understanding of the factors controlling the ice dynamics. In addition, estimating the magnitude of the internal stress gradients on drifting sea ice floes generated by surrounding ice cover is important for modeling operations, informing the design of offshore structures and vessels in ice environments, and for the proper calibration of Discrete Element Models (DEM) of fields of drifting ice floes. In the spring of 2015 and 2016, four sea ice floes offshore Makkovik, Labrador were tagged with satellite-linked ice tracking buoys along with one satellite-linked weather station on each floe to transmit wind speed and direction. Twenty satellite-linked Lagrangian surface ocean current tracking buoys were also deployed in the open water adjacent to the targeted ice floes. In this paper, the dynamics of the four ice floes are explored in terms of the relative proportions which were forced by the wind, current, sea surface topography, Coriolis, and internal stress gradients. The internal ice stress gradients are calculated as residuals between the observed accelerations of the floes as measured by the tracking buoys and the sums of the other metocean forcings. Results show that internal ice stress gradients accounted for up to 50% of the observed forcing on the floes, and may have reached up to around 0.19 kPa.

The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report.

Science.gov (United States)

Monclair, Tom; Brodeur, Garrett M; Ambros, Peter F; Brisse, Hervé J; Cecchetto, Giovanni; Holmes, Keith; Kaneko, Michio; London, Wendy B; Matthay, Katherine K; Nuchtern, Jed G; von Schweinitz, Dietrich; Simon, Thorsten; Cohn, Susan L; Pearson, Andrew D J

2009-01-10

The International Neuroblastoma Risk Group (INRG) classification system was developed to establish a consensus approach for pretreatment risk stratification. Because the International Neuroblastoma Staging System (INSS) is a postsurgical staging system, a new clinical staging system was required for the INRG pretreatment risk classification system. To stage patients before any treatment, the INRG Task Force, consisting of neuroblastoma experts from Australia/New Zealand, China, Europe, Japan, and North America, developed a new INRG staging system (INRGSS) based on clinical criteria and image-defined risk factors (IDRFs). To investigate the impact of IDRFs on outcome, survival analyses were performed on 661 European patients with INSS stages 1, 2, or 3 disease for whom IDRFs were known. In the INGRSS, locoregional tumors are staged L1 or L2 based on the absence or presence of one or more of 20 IDRFs, respectively. Metastatic tumors are defined as stage M, except for stage MS, in which metastases are confined to the skin, liver, and/or bone marrow in children younger than 18 months of age. Within the 661-patient cohort, IDRFs were present (ie, stage L2) in 21% of patients with stage 1, 45% of patients with stage 2, and 94% of patients with stage 3 disease. Patients with INRGSS stage L2 disease had significantly lower 5-year event-free survival than those with INRGSS stage L1 disease (78% +/- 4% v 90% +/- 3%; P = .0010). Use of the new staging (INRGSS) and risk classification (INRG) of neuroblastoma will greatly facilitate the comparison of risk-based clinical trials conducted in different regions of the world.

Interactions between internal forces, body stiffness, and fluid environment in a neuromechanical model of lamprey swimming.

Science.gov (United States)

Tytell, Eric D; Hsu, Chia-Yu; Williams, Thelma L; Cohen, Avis H; Fauci, Lisa J

2010-11-16

Animal movements result from a complex balance of many different forces. Muscles produce force to move the body; the body has inertial, elastic, and damping properties that may aid or oppose the muscle force; and the environment produces reaction forces back on the body. The actual motion is an emergent property of these interactions. To examine the roles of body stiffness, muscle activation, and fluid environment for swimming animals, a computational model of a lamprey was developed. The model uses an immersed boundary framework that fully couples the Navier-Stokes equations of fluid dynamics with an actuated, elastic body model. This is the first model at a Reynolds number appropriate for a swimming fish that captures the complete fluid-structure interaction, in which the body deforms according to both internal muscular forces and external fluid forces. Results indicate that identical muscle activation patterns can produce different kinematics depending on body stiffness, and the optimal value of stiffness for maximum acceleration is different from that for maximum steady swimming speed. Additionally, negative muscle work, observed in many fishes, emerges at higher tail beat frequencies without sensory input and may contribute to energy efficiency. Swimming fishes that can tune their body stiffness by appropriately timed muscle contractions may therefore be able to optimize the passive dynamics of their bodies to maximize peak acceleration or swimming speed.

Experimental investigation of Surface Roughness and Cutting force in CNC Turning - A Review

Directory of Open Access Journals (Sweden)

Dhiraj Patel

2014-08-01

Full Text Available The main purpose of this review paper is to check whether quality lies within desired tolerance level which can be accepted by the customers. So, experimental investigation surface roughness and cutting force using various CNC machining parameters including spindle speed (N, feed rate (f, and depth of cut (d,flow rate (Q and insert nose radius (r. As such, a solemn attempt is made in this paper to investigate the response parameters, viz., Cutting force and Surface Roughness (Ra a by experimentation on EN 19 turning process. The Design of experiments is carried-out considering Taguchi Technique with four input parameters, namely, spindle speed, feed rate, and depth of cut, flow rate and insert nose radius .The experiments are conducted considering the above materials for L16 and then the impact of each parameter is estimated by ANOAVA. Then the regression analysis is carried-out to find the trend of the response of each material. This experimental study aims at taguchi method has been applied for finding the effect on surface roughness and cutting force by various process parameters. And after that we can easily find out that which parameter will be more affect.

Atlantic Meridional Overturning Circulation response to idealized external forcing

Energy Technology Data Exchange (ETDEWEB)

Park, W.; Latif, M. [Leibniz-Institut fuer Meereswissenschaften an der Universitaet Kiel, Kiel (Germany)

2012-10-15

The response of the Atlantic Meridional Overturning Circulation (AMOC) to idealized external (solar) forcing is studied in terms of the internal (unforced) AMOC modes with the Kiel Climate Model (KCM), a coupled atmosphere-ocean-sea ice general circulation model. The statistical investigation of KCM's internal AMOC variability obtained from a multi-millennial control run yields three distinct modes: a multi-decadal mode with a period of about 60 years, a quasi-centennial mode with a period of about 100 years and a multi-centennial mode with a period of about 300-400 years. Most variance is explained by the multi-centennial mode, and the least by the quasi-centennial mode. The solar constant varies sinusoidally with two different periods (100 and 60 years) in forced runs with KCM. The AMOC response to the external forcing is rather complex and nonlinear. It involves strong changes in the frequency structure of the variability. While the control run depicts multi-timescale behavior, the AMOC variability in the experiment with 100 year forcing period is channeled into a relatively narrow band centered near the forcing period. It is the quasi-centennial AMOC mode with a period of just under 100 years which is excited, although it is heavily damped in the control run. Thus, the quasi-centennial mode retains its period which does not correspond exactly to the forcing period. Surprisingly, the quasi-centennial mode is also most strongly excited when the forcing period is set to 60 years, the period of the multi-decadal mode which is rather prominent in the control run. It is largely the spatial structure of the forcing rather than its period that determines which of the three internal AMOC modes is excited. The results suggest that we need to understand the full modal structure of the internal AMOC variability in order to understand the circulation's response to external forcing. This could be a challenge for climate models: we cannot necessarily expect that the

(Environmental investigation of ground water contamination at Wright- Patterson Air Force Base, Ohio)

Energy Technology Data Exchange (ETDEWEB)

1991-10-01

This Health and Safety Plan (HSP) was developed for the Environmental Investigation of Ground-water Contamination Investigation at Wright-Patterson Air Force Base near Dayton, Ohio, based on the projected scope of work for the Phase 1, Task 4 Field Investigation. The HSP describes hazards that may be encountered during the investigation, assesses the hazards, and indicates what type of personal protective equipment is to be used for each task performed. The HSP also addresses the medical monitoring program, decontamination procedures, air monitoring, training, site control, accident prevention, and emergency response.

Bimanual elbow robotic orthoses: preliminary investigations on an impairment force feedback rehabilitation method

Directory of Open Access Journals (Sweden)

Gil eHerrnstadt

2015-03-01

Full Text Available Modern rehabilitation practices have begun integrating robots, recognizing their significant role in recovery. New and alternative stroke rehabilitation treatments are essential to enhance efficacy and mitigate associated health costs. Today’s robotic interventions can play a significant role in advancing rehabilitation. In addition, robots have an inherent ability to perform tasks accurately and reliably and are typically well suited to measure and quantify performance.Most rehabilitation strategies predominantly target activation of the paretic arm. However, bimanual upper limb rehabilitation research suggests potential in enhancing functional recovery. Moreover studies suggest limb coordination and synchronization can improve treatment efficacy.In this preliminary study, we aimed to investigate and validate our user-driven bimanual system in a reduced intensity rehab practice. A Bimanual Wearable Robotic Device (BWRD with a Master-Slave configuration for the elbow joint was developed to carry out the investigation. The BWRD incorporates position and force sensors for which respective control loops are implemented, and offers varying modes of operation ranging from passive to active training. The proposed system enables the perception of the movements, as well as the forces applied by the hemiparetic arm, with the non-hemiparetic arm. Eight participants with chronic unilateral stroke were recruited to participate in a total of three one-hour sessions per participant, delivered in a week. Participants underwent pre and post training functional assessments along with proprioceptive measures. The post assessment was performed at the end of the last training session.The protocol was designed to engage the user in an assortment of static and dynamic arm matching and opposing tasks. The training incorporates force feedback movements, force feedback positioning, and force matching tasks with same and opposite direction movements. We are able to

Investigation of the hydrodynamic model test of forced rolling for a barge using PIV

Directory of Open Access Journals (Sweden)

WANG Xiaoqiang

2017-03-01

Full Text Available In order to study the physical details of viscous flow in ship roll motions and improve the accuracy of ship roll damping numerical simulation, the application of the Particle Image Velocimetry (PIV technique is investigated in model tests of forced ship rolling in calm water. The hydrodynamic force and flow field at the bilge region are simultaneously measured for barges at different amplitudes and frequencies in which the self-made forced rolling facility was used. In the model test, the viscous flow variation with the time around the bilge region was studied during ship rolling motion. The changes in ship roll damping coefficients with the rolling amplitude and period were also investigated. A comparison of the model test results with the Computational Fluid Dynamics(CFDresults shows that the numerical ship roll damping coefficients agree well with the model test results, while the differences in the local flow details exist between the CFD results and model test results. Further research into the model test technique and CFD application is required.

Force Concept Inventory-based multiple-choice test for investigating students’ representational consistency

Directory of Open Access Journals (Sweden)

Pasi Nieminen

2010-08-01

Full Text Available This study investigates students’ ability to interpret multiple representations consistently (i.e., representational consistency in the context of the force concept. For this purpose we developed the Representational Variant of the Force Concept Inventory (R-FCI, which makes use of nine items from the 1995 version of the Force Concept Inventory (FCI. These original FCI items were redesigned using various representations (such as motion map, vectorial and graphical, yielding 27 multiple-choice items concerning four central concepts underpinning the force concept: Newton’s first, second, and third laws, and gravitation. We provide some evidence for the validity and reliability of the R-FCI; this analysis is limited to the student population of one Finnish high school. The students took the R-FCI at the beginning and at the end of their first high school physics course. We found that students’ (n=168 representational consistency (whether scientifically correct or not varied considerably depending on the concept. On average, representational consistency and scientifically correct understanding increased during the instruction, although in the post-test only a few students performed consistently both in terms of representations and scientifically correct understanding. We also compared students’ (n=87 results of the R-FCI and the FCI, and found that they correlated quite well.

Policy lessons from comparing mortality from two global forces: international terrorism and tobacco

Directory of Open Access Journals (Sweden)

Wilson Nick

2005-12-01

Full Text Available Abstract Background The aim of this study was to compare the mortality burdens from two global impacts on mortality: international terrorism and the major cause of preventable death in developed countries – tobacco use. We also sought to examine the similarities and differences between these two causes of mortality so as to better inform the policy responses directed at prevention. Methods Data on deaths from international terrorism were obtained from a US State Department database for 1994–2003. Estimates for tobacco-attributable deaths were based on Peto et al 2003. The countries were 37 developed and East European countries. Results and discussion The collective annualized mortality burden from tobacco was approximately 5700 times that of international terrorism. The ratio of annual tobacco to international terrorism deaths was lowest for the United States at 1700 times, followed by Russia at 12,900 times. The tobacco death burden in all these countries was equivalent to the impact of an 11 September type terrorist attack every 14 hours. Different perceptions of risk may contribute to the relative lack of a policy response to tobacco mortality, despite its relatively greater scale. The lack is also despite tobacco control having a stronger evidence base for the prevention measures used. Conclusion This comparison highlights the way risk perception may determine different policy responses to global forces causing mortality. Nevertheless, the large mortality differential between international terrorism and tobacco use has policy implications for informing the rational use of resources to prevent premature death.

The effect of force feedback delay on stiffness perception and grip force modulation during tool-mediated interaction with elastic force fields.

Science.gov (United States)

Leib, Raz; Karniel, Amir; Nisky, Ilana

2015-05-01

During interaction with objects, we form an internal representation of their mechanical properties. This representation is used for perception and for guiding actions, such as in precision grip, where grip force is modulated with the predicted load forces. In this study, we explored the relationship between grip force adjustment and perception of stiffness during interaction with linear elastic force fields. In a forced-choice paradigm, participants probed pairs of virtual force fields while grasping a force sensor that was attached to a haptic device. For each pair, they were asked which field had higher level of stiffness. In half of the pairs, the force feedback of one of the fields was delayed. Participants underestimated the stiffness of the delayed field relatively to the nondelayed, but their grip force characteristics were similar in both conditions. We analyzed the magnitude of the grip force and the lag between the grip force and the load force in the exploratory probing movements within each trial. Right before answering which force field had higher level of stiffness, both magnitude and lag were similar between delayed and nondelayed force fields. These results suggest that an accurate internal representation of environment stiffness and time delay was used for adjusting the grip force. However, this representation did not help in eliminating the bias in stiffness perception. We argue that during performance of a perceptual task that is based on proprioceptive feedback, separate neural mechanisms are responsible for perception and action-related computations in the brain. Copyright © 2015 the American Physiological Society.

Hypersonic force measurements using internal balance based on optical micromachined Fabry-Perot interferometry

Science.gov (United States)

Qiu, Huacheng; Min, Fu; Zhong, Shaolong; Song, Xin; Yang, Yanguang

2018-03-01

Force measurements using wind tunnel balance are necessary for determining a variety of aerodynamic performance parameters, while the harsh environment in hypersonic flows requires that the measurement instrument should be reliable and robust, in against strong electromagnetic interference, high vacuum, or metal (oxide) dusts. In this paper, we demonstrated a three-component internal balance for hypersonic aerodynamic force measurements, using novel optical micromachined Fabry-Perot interferometric (FPI) strain gauges as sensing elements. The FPI gauges were fabricated using Micro-Opto-Electro-Mechanical Systems (MOEMS) surface and bulk fabrication techniques. High-reflectivity coatings are used to form a high-finesse Fabry-Perot cavity, which benefits a high resolution. Antireflective and passivation coatings are used to reduce unwanted interferences. The FPI strain gauge based balance has been calibrated and evaluated in a Mach 5 hypersonic flow. The results are compared with the traditional technique using the foil resistive strain gauge balance, indicating that the proposed balance based on the MOEMS FPI strain gauge is reliable and robust and is potentially suitable for the hypersonic wind tunnel harsh environment.

The Influence of Flexibility Coefficient on the Size of Internal Forces and Deformations in Circular Plates on Elastic Medium

Directory of Open Access Journals (Sweden)

Şandru Mirela

2016-09-01

Full Text Available This paper presents an analytical study which deals with the behavior of the circular plates in bending theory, considering the soil-structure interaction under Winkler's hypothesis. It was intended to illustrate the variation of internal forces and deformations according to the flexibility coefficient of plates considering three models: a fixed solid circular plate subjected to a uniformly distributed load, a fixed solid circular plate acted by a displacement applied on the exterior contour and a solid plate subjected to a temperature gradient. For this study the computation relations were written as a product between a dimensional and a non-dimensional factor, the last one indicating the variation of internal forces and deformations. For each type of action there are presented results obtained using the finite element method to illustrate the differences between this method and the analytical computation.

A Modeling Framework to Investigate the Radial Component of the Pushrim Force in Manual Wheelchair Propulsion

Directory of Open Access Journals (Sweden)

Ackermann Marko

2015-01-01

Full Text Available The ratio of tangential to total pushrim force, the so-called Fraction Effective Force (FEF, has been used to evaluate wheelchair propulsion efficiency based on the fact that only the tangential component of the force on the pushrim contributes to actual wheelchair propulsion. Experimental studies, however, consistently show low FEF values and recent experimental as well as modelling investigations have conclusively shown that a more tangential pushrim force direction can lead to a decrease and not increase in propulsion efficiency. This study aims at quantifying the contributions of active, inertial and gravitational forces to the normal pushrim component. In order to achieve this goal, an inverse dynamics-based framework is proposed to estimate individual contributions to the pushrim forces using a model of the wheelchair-user system. The results show that the radial pushrim force component arise to a great extent due to purely mechanical effects, including inertial and gravitational forces. These results corroborate previous findings according to which radial pushrim force components are not necessarily a result of inefficient propulsion strategies or hand-rim friction requirements. This study proposes a novel framework to quantify the individual contributions of active, inertial and gravitational forces to pushrim forces during wheelchair propulsion.

The new Rotterdam Rules: An overwiew on the main differences with the international regulations in force on carriage of goods by sea

OpenAIRE

Rimaboschi, Massimiliano

2009-01-01

This new instrument, that will enter into force once it has been ratified by at least twenty States, deals with the international carriage of goods and is closely connected with the international trade. International transport law is currently regulated by two main international Conventions, the Hague Rules and the Hamburg Rules. Many countries have adopted the Hague Rules as amended by two Protocols, respectively adopted in Brussels on 1968 (the Hague Visby Rules – 30 contracting States) and...

The Effect of Foot Progression Angle on Knee Joint Compression Force during Walking

DEFF Research Database (Denmark)

Baldvinsson, Henrik Koblauch; Heilskov-Hansen, Thomas; Alkjær, Tine

2013-01-01

males walked at a fixed speed of 4.5 km/h under three conditions: Normal walking, internally rotated and externally rotated. All gait-trials were recorded by six infrared cameras. Net joint moments were calculated by 3D inverse dynamics. The results revealed that the medial knee joint compartment......It is unclear how rotations of the lower limb affect the knee joint compression forces during walking. Increases in the frontal plane knee moment have been reported when walking with internally rotated feet and a decrease when walking with externally rotated feet. The aim of this study...... was to investigate the knee joint compressive forces during walking with internal, external and normal foot rotation and to determine if the frontal plane knee joint moment is an adequate surrogate for the compression forces in the medial and lateral knee joint compartments under such gait modifications. Ten healthy...

Computer Network Attack and the Use of Force in International Law: Thoughts on a Normative Framework

Science.gov (United States)

1999-06-01

interpretive consideration. See Vienna Convention, supra note 51, art. 31(3). 69 On economic sanctions, see Paul Szasz , The Law of Economic Sanctions...COMPUTER NETWORK ATTACK AND THE USE OF FORCE IN INTERNATIONAL LAW : THOUGHTS ON A NORMATIVE FRAMEWORK MICHAEL N...Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law , no person shall be subject to a

Comparative investigations of tablet crushing force testers

DEFF Research Database (Denmark)

Sonnergaard, Jørn; Jensen, C.G.; Poulsen, L.

2005-01-01

The performance of 16 tablet breaking force testers was evaluated in terms of accuracy, reproducibility and repeatability. Three tablet formulations with different plastic or brittle deformation mechanisms and with target breaking forces of 50, 100 and 150 N were tested. Statistically significant...... by the concept of components of variance was 5-7 % depending on the model tablet excipient. The standard deviation within testers (repeatability) was affected by the type of model formulation showing increasing variability with increasing brittleness of the compressed material. No specific effect of altering...

Atomic force microscopic investigation of commercial pressure sensitive adhesives for forensic analysis.

Science.gov (United States)

Canetta, Elisabetta; Adya, Ashok K

2011-07-15

Pressure sensitive adhesive (PSA), such as those used in packaging and adhesive tapes, are very often encountered in forensic investigations. In criminal activities, packaging tapes may be used for sealing packets containing drugs, explosive devices, or questioned documents, while adhesive and electrical tapes are used occasionally in kidnapping cases. In this work, the potential of using atomic force microscopy (AFM) in both imaging and force mapping (FM) modes to derive additional analytical information from PSAs is demonstrated. AFM has been used to illustrate differences in the ultrastructural and nanomechanical properties of three visually distinguishable commercial PSAs to first test the feasibility of using this technique. Subsequently, AFM was used to detect nanoscopic differences between three visually indistinguishable PSAs. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Part-time careers in academic internal medicine: a report from the association of specialty professors part-time careers task force on behalf of the alliance for academic internal medicine.

Science.gov (United States)

Linzer, Mark; Warde, Carole; Alexander, R Wayne; Demarco, Deborah M; Haupt, Allison; Hicks, Leroi; Kutner, Jean; Mangione, Carol M; Mechaber, Hilit; Rentz, Meridith; Riley, Joanne; Schuster, Barbara; Solomon, Glen D; Volberding, Paul; Ibrahim, Tod

2009-10-01

To establish guidelines for more effectively incorporating part-time faculty into departments of internal medicine, a task force was convened in early 2007 by the Association of Specialty Professors. The task force used informal surveys, current literature, and consensus building among members of the Alliance for Academic Internal Medicine to produce a consensus statement and a series of recommendations. The task force agreed that part-time faculty could enrich a department of medicine, enhance workforce flexibility, and provide high-quality research, patient care, and education in a cost-effective manner. The task force provided a series of detailed steps for operationalizing part-time practice; to do so, key issues were addressed, such as fixed costs, malpractice insurance, space, cross-coverage, mentoring, career development, productivity targets, and flexible scheduling. Recommendations included (1) increasing respect for work-family balance, (2) allowing flexible time as well as part-time employment, (3) directly addressing negative perceptions about part-time faculty, (4) developing policies to allow flexibility in academic advancement, (5) considering part-time faculty as candidates for leadership positions, (6) encouraging granting agencies, including the National Institutes of Health and Veterans Administration, to consider part-time faculty as eligible for research career development awards, and (7) supporting future research in "best practices" for incorporating part-time faculty into academic departments of medicine.

INVESTIGATION OF POLYMER SURFACES USING SCANNING FORCE MICROSCOPY (SFM) - A NEW DIRECT LOOK ON OLD POLYMER PROBLEMS

NARCIS (Netherlands)

GRIM, PCM; BROUWER, HJ; SEYGER, RM; OOSTERGETEL, GT; BERGSMASCHUTTER, WG; ARNBERG, AC; GUTHNER, P; DRANSFELD, K; HADZIIOANNOU, G

In this contribution, the general concepts of force microscopy will be presented together with its application to polymer surfaces (Ref.1). Several examples will be presented to illustrate that force microscopy is a powerful and promising tool for investigation of (polymer) surfaces, such as the

Methodological recommendations for cognition trials in bipolar disorder by the International Society for Bipolar Disorders Targeting Cognition Task Force

DEFF Research Database (Denmark)

Miskowiak, K W; Burdick, K E; Martinez-Aran, A

2017-01-01

OBJECTIVES: To aid the development of treatment for cognitive impairment in bipolar disorder, the International Society for Bipolar Disorders (ISBD) convened a task force to create a consensus-based guidance paper for the methodology and design of cognition trials in bipolar disorder. METHODS...... of treatments to illness stage and using a multimodal approach. CONCLUSIONS: This ISBD task force guidance paper provides the first consensus-based recommendations for cognition trials in bipolar disorder. Adherence to these recommendations will likely improve the sensitivity in detecting treatment efficacy...

Introduction to the IEEE International Symposium on Applications of Ferroelectrics and International Symposium on Piezoresponse Force Microscopy and Nanoscale Phenomena in Polar Materials.

Science.gov (United States)

Ye, Zuo-Guang; Tan, Xiaoli; Bokov, Alexei A

2012-09-01

The 20th IEEE International Symposium on Applications of Ferroelectrics (ISAF) was held on July 24-27, 2011, in Vancouver, British Columbia, Canada, jointly with the International Symposium on Piezoresponse Force Microscopy and Nanoscale Phenomena in Polar Materials (PFM). Over a period of four days, approximately 400 scientists, engineers, and students from around the world presented their work and discussed the latest developments in the field of ferroelectrics, related materials, and their applications. It is particularly encouraging to see that a large number of students (115) were attracted to the joint conference and presented high-quality research works. This trend is not only important to this conference series, but more importantly, it is vital to the future of the ferroelectrics field.

Imaging of RNA in situ hybridization by atomic force microscopy

NARCIS (Netherlands)

Kalle, W.H.J.; Macville, M.V.E.; van de Corput, M.P.C.; de Grooth, B.G.; Tanke, H.J.; Raap, A.K.

In this study we investigated the possibility of imaging internal cellular molecules after cytochemical detection with atomic force microscopy (AFM). To this end, rat 9G and HeLa cells were hybridized with haptenized probes for 28S ribosomal RNA, human elongation factor mRNA and cytomegalovirus

Politics and Graduate Medical Education in Internal Medicine: A Dynamic Landscape.

Science.gov (United States)

Wardrop, Richard M; Berkowitz, Lee R

2017-02-01

The promotion of change and growth within medical education is oftentimes the result of a complex mix of societal, cultural and economic forces. Graduate medical education in internal medicine is not immune to these forces. Several entities and organizations can be identified as having a major influence on internal medicine training and graduate medical education as a whole. We have reviewed how this is effectively accomplished through these entities and organizations. The result is a constantly changing and dynamic landscape for internal medicine training. Copyright © 2017 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

Does an increase in compression force really improve visual image quality in mammography? – An initial investigation

International Nuclear Information System (INIS)

Mercer, C.E.; Hogg, P.; Cassidy, S.; Denton, E.R.E.

2013-01-01

Objective: Literature speculates that visual image quality (IQ) and compression force levels may be directly related. This small study investigates whether a relationship exists between compression force levels and visual IQ. Method: To investigate how visual IQ varies with different levels of compression force, 39 clients were selected over a 6 year screening period that had received markedly different amounts of compression force on each of their three sequential screens. Images for the 3 screening episodes for all women were scored visually using 3 different IQ scales. Results: Correlation coefficients between the 3 IQ scales were positive and high (0.82, 0.9 and 0.85). For the scales, the IQ scores their correlation does not vary significantly, even though different compression levels had been applied. Kappa IQ scale 1: 0.92, 0.89, 0.89. ANOVA IQ scale 2: p = 0.98, p = 0.55, p = 0.56. ICC IQ scale 3: 0.97, 0.93, 0.91. Conclusion: For the 39 clients there is no difference in visual IQ when different amounts of compression are applied. We believe that further work should be conducted into compression force and image quality as ‘higher levels’ of compression force may not be justified in the attainment of suitable visual image quality

EXPERIMENTAL INVESTIGATION OF THE IMPACT OF FLIGHT SPEED ON DRAG FORCE IN THE AUTOGYRO MODEL

Directory of Open Access Journals (Sweden)

Zbigniew Czyż

2015-05-01

Full Text Available The paper presents the experimental investigation of the impact of velocity on drag force in the autogyro model. One of the methods which simulate motion of the flying object consists of using a wind tunnel. In this case, test object is stationary and the motion of air is forced by e.g. a special fan. The costs related with renting and the wind tunnel service are still very high. In this paper, the motion of the autogyro with respect to the air, was produced by fixing this model with scale to measure the drag force on the passenger car roof. The position of the object relative to the vehicle was checked on the basis of numerical analysis of the airflow around this vehicle. Based on the investigations, the field of velocity and pressure, and air flow formed around the contour of the vehicle which have been chosen, were determined. In addition, the drag force characteristic was determined as a function of velocity and it was compared with the values from the numerical analysis. This research is a form of verifying opportunities for this type of research on vehicles. The conclusions derived from the analysis of the results will be used in the future to carry out further research.

Internal phase transition induced by external forces in Finsler geometric model for membranes

Science.gov (United States)

Koibuchi, Hiroshi; Shobukhov, Andrey

2016-10-01

In this paper, we numerically study an anisotropic shape transformation of membranes under external forces for two-dimensional triangulated surfaces on the basis of Finsler geometry. The Finsler metric is defined by using a vector field, which is the tangential component of a three-dimensional unit vector σ corresponding to the tilt or some external macromolecules on the surface of disk topology. The sigma model Hamiltonian is assumed for the tangential component of σ with the interaction coefficient λ. For large (small) λ, the surface becomes oblong (collapsed) at relatively small bending rigidity. For the intermediate λ, the surface becomes planar. Conversely, fixing the surface with the boundary of area A or with the two-point boundaries of distance L, we find that the variable σ changes from random to aligned state with increasing of A or L for the intermediate region of λ. This implies that an internal phase transition for σ is triggered not only by the thermal fluctuations, but also by external mechanical forces. We also find that the frame (string) tension shows the expected scaling behavior with respect to A/N (L/N) at the intermediate region of A (L) where the σ configuration changes between the disordered and ordered phases. Moreover, we find that the string tension γ at sufficiently large λ is considerably smaller than that at small λ. This phenomenon resembles the so-called soft-elasticity in the liquid crystal elastomer, which is deformed by small external tensile forces.

The Use of Force in Modern Counter-Terrorism: International Legal and Political Aspects

Directory of Open Access Journals (Sweden)

Elizaveta Sergeevna Gromoglasova

2016-12-01

Full Text Available The paper reviews the recent practice of the use of military force in extraterritorial counter-terrorist operations. It argues that nowadays we're witnessing a new stage in the 'war on terror' that's still going on. Although the most of the modern counter-terrorist operations like, for example, the US-led coalition against ISIL in Iraq are being conducted at the request of the affected government, the major risks of expanding and misuse of the right on individual or collective self-defense enshrined in the UN Charter are still present. This can be illustrated by reference to the US air strikes on ISIL in Syria that have been undertaken without consent of Syrian government. But the challenges emerging from 'failed states' and rise of new more radical and militant terrorist movements (ISIL, Ash-Shabaab, Boko Haram and others change the perceptions of legality of extraterritorial counter-terrorist force. The approach which reaffirms responsibility of the state for suppressing terrorist groups operating from within its territory seems to become more and more acceptable. Accordingly, if the state can't suppress terrorist activity it should accept the counter-terrorist intervention on its territory. Nevertheless, jus in bello norms (first of all international humanitarian law remain stringent legal framework for actual use of counter-terrorist military force. The paper concludes that overall political legitimacy of the modern military counter-terrorist operations should be accessed in terms of their humanitarian impact and consequences.

International Acquisitons in Multinacionals: Under a Force Field

Directory of Open Access Journals (Sweden)

Américo da Costa Ramos Filho

2010-12-01

Full Text Available The purpose of this essay is to debate the performance of multinational companies concerning the management alternatives of their foreign unities, especially the ones derived from acquisitions, with consequences on the interaction between the headquarters and its subsidiaries or colligates and the managerial learning and knowledge associated to this process. First the problematic of internationalized companies by foreign direct investments – FDI’s, mainly by acquisitions and strategic alliances, is discussed. The intensity of the assimilation and interchange of values and practices within organizations in interacting process is stressed, including a set of typologies derived from the existing related literature. After this, a more specific approach about intra and interorganization aspects of the multinationals is performed, related to strategies, competences and roles of headquarters and subsidiaries, as well as their impact on the knowledge flux and its derived learning modes, evolving a established typologies set. The next step is to discuss two visions about the opposition between the universal and the particular in international management, with global and contextual aspects: a convergence-divergence opposition, like a force field, impacting on the knowledge transfer. Finally, some concluding comments are made, emphasizing, for the purpose of contribution, another type of multinationals typology relating the convergence-divergence duality to the organizational and national levels, as well the positioning of the companies in the resulted matrix.

Investigation of polyelectrolyte desorption by single molecule force spectroscopy

International Nuclear Information System (INIS)

Friedsam, C; Seitz, M; Gaub, H E

2004-01-01

Single molecule force spectroscopy has evolved into a powerful method for the investigation of intra- and intermolecular interactions at the level of individual molecules. Many examples, including the investigation of the dynamic properties of complex biological systems as well as the properties of covalent bonds or intermolecular transitions within individual polymers, are reported in the literature. The technique has recently been extended to the systematic investigation of desorption processes of individual polyelectrolyte molecules adsorbed on generic surfaces. The stable covalent attachment of polyelectrolyte molecules to the AFM-tip provides the possibility of performing long-term measurements with the same set of molecules and therefore allows the in situ observation of the impact of environmental changes on the adsorption behaviour of individual molecules. Different types of interactions, e.g. electrostatic or hydrophobic interactions, that determine the adsorption process could be identified and characterized. The experiments provided valuable details that help to understand the nature and the properties of non-covalent interactions, which is helpful with regard to biological systems as well as for technical applications. Apart from this, desorption experiments can be utilized to characterize the properties of surfaces or polymer coatings. Therefore they represent a versatile tool that can be further developed in terms of various aspects

Supplemental site inspection for Air Force Plant 59, Johnson City, New York, Volume 1: Investigation report

Energy Technology Data Exchange (ETDEWEB)

Nashold, B.; Rosenblatt, D.; Hau, J. [and others

1995-08-01

This summary describes a Supplemental Site Inspection (SSI) conducted by Argonne National Laboratory (ANL) at Air Force Plant 59 (AFP 59) in Johnson City, New York. All required data pertaining to this project were entered by ANL into the Air Force-wide Installation Restoration Program Information System (IRPIMS) computer format and submitted to an appropriate authority. The work was sponsored by the United States Air Force as part of its Installation Restoration Program (IRP). Previous studies had revealed the presence of contaminants at the site and identified several potential contaminant sources. Argonne`s study was conducted to answer questions raised by earlier investigations.

International Veterinary Epilepsy Task Force consensus report on epilepsy definition, classification and terminology in companion animals

DEFF Research Database (Denmark)

Berendt, Mette; Farquhar, Robyn G; Mandigers, Paul J J

2015-01-01

the years reflecting always in parts the current proposals coming from the human epilepsy organisation the International League Against Epilepsy (ILAE). It has however not been possible to gain agreed consensus, "a common language", for the classification and terminology used between veterinary and human...... neurologists and neuroscientists, practitioners, neuropharmacologists and neuropathologists. This has led to an unfortunate situation where different veterinary publications and textbook chapters on epilepsy merely reflect individual author preferences with respect to terminology, which can be confusing...... to the readers and influence the definition and diagnosis of epilepsy in first line practice and research studies.In this document the International Veterinary Epilepsy Task Force (IVETF) discusses current understanding of canine epilepsy and presents our 2015 proposal for terminology and classification...

Soliton ratchetlike dynamics by ac forces with harmonic mixing

DEFF Research Database (Denmark)

Salerno, Mario; Zolotaryuk, Yaroslav

2002-01-01

The possibility of unidirectional motion of a kink (topological soliton) of a dissipative sine-Gordon equation in the presence of ac forces with harmonic mixing (at least biharmonic) and of zero mean, is presented. The dependence of the kink mean velocity on system parameters is investigated...... numerically and the results are compared with a perturbation analysis based on a point-particle representation of the soliton. We find that first order perturbative calculations lead to incomplete descriptions, due to the important role played by the soliton-phonon interaction in establishing the phenomenon...... in the system. Effective soliton transport is achieved when the internal mode and the external force get phase locked. We find that for kinks driven by biharmonic drivers consisting of the superposition of a fundamental driver with its first odd harmonic, the transport arises only due to this internal mode...

Treating juvenile idiopathic arthritis to target: recommendations of an international task force.

Science.gov (United States)

Ravelli, Angelo; Consolaro, Alessandro; Horneff, Gerd; Laxer, Ronald M; Lovell, Daniel J; Wulffraat, Nico M; Akikusa, Jonathan D; Al-Mayouf, Sulaiman M; Antón, Jordi; Avcin, Tadej; Berard, Roberta A; Beresford, Michael W; Burgos-Vargas, Ruben; Cimaz, Rolando; De Benedetti, Fabrizio; Demirkaya, Erkan; Foell, Dirk; Itoh, Yasuhiko; Lahdenne, Pekka; Morgan, Esi M; Quartier, Pierre; Ruperto, Nicolino; Russo, Ricardo; Saad-Magalhães, Claudia; Sawhney, Sujata; Scott, Christiaan; Shenoi, Susan; Swart, Joost F; Uziel, Yosef; Vastert, Sebastiaan J; Smolen, Josef S

2018-06-01

Recent therapeutic advances in juvenile idiopathic arthritis (JIA) have made remission an achievable goal for most patients. Reaching this target leads to improved outcomes. The objective was to develop recommendations for treating JIA to target. A Steering Committee formulated a set of recommendations based on evidence derived from a systematic literature review. These were subsequently discussed, amended and voted on by an international Task Force of 30 paediatric rheumatologists in a consensus-based, Delphi-like procedure. Although the literature review did not reveal trials that compared a treat-to-target approach with another or no strategy, it provided indirect evidence regarding an optimised approach to therapy that facilitated development of recommendations. The group agreed on six overarching principles and eight recommendations. The main treatment target, which should be based on a shared decision with parents/patients, was defined as remission, with the alternative target of low disease activity. The frequency and timeline of follow-up evaluations to ensure achievement and maintenance of the target depend on JIA category and level of disease activity. Additional recommendations emphasise the importance of ensuring adequate growth and development and avoiding long-term systemic glucocorticoid administration to maintain the target. All items were agreed on by more than 80% of the members of the Task Force. A research agenda was formulated. The Task Force developed recommendations for treating JIA to target, being aware that the evidence is not strong and needs to be expanded by future research. These recommendations can inform various stakeholders about strategies to reach optimal outcomes for JIA. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Methodological recommendations for cognition trials in bipolar disorder by the International Society for Bipolar Disorders Targeting Cognition Task Force

DEFF Research Database (Denmark)

Miskowiak, K W; Burdick, K E; Martinez-Aran, A

2017-01-01

OBJECTIVES: To aid the development of treatment for cognitive impairment in bipolar disorder, the International Society for Bipolar Disorders (ISBD) convened a task force to create a consensus-based guidance paper for the methodology and design of cognition trials in bipolar disorder. METHODS...... symptoms and concomitant medication. Task force recommendations are to: (i) enrich trials with objectively measured cognitively impaired patients; (ii) generally select a broad cognitive composite score as the primary outcome and a functional measure as a key secondary outcome; and (iii) include remitted...... of treatments to illness stage and using a multimodal approach. CONCLUSIONS: This ISBD task force guidance paper provides the first consensus-based recommendations for cognition trials in bipolar disorder. Adherence to these recommendations will likely improve the sensitivity in detecting treatment efficacy...

Patterning in systems driven by nonlocal external forces.

Science.gov (United States)

Luneville, L; Mallick, K; Pontikis, V; Simeone, D

2016-11-01

This work focuses on systems displaying domain patterns resulting from competing external and internal dynamics. To this end, we introduce a Lyapunov functional capable of describing the steady states of systems subject to external forces, by adding nonlocal terms to the Landau Ginzburg free energy of the system. Thereby, we extend the existing methodology treating long-range order interactions, to the case of external nonlocal forces. By studying the quadratic term of this Lyapunov functional, we compute the phase diagram in the temperature versus external field and we determine all possible modulated phases (domain patterns) as a function of the external forces and the temperature. Finally, we investigate patterning in chemical reactive mixtures and binary mixtures under irradiation, and we show that the last case opens the path toward micro-structural engineering of materials.

Investigation of integrin expression on the surface of osteoblast-like cells by atomic force microscopy

International Nuclear Information System (INIS)

Caneva Soumetz, Federico; Saenz, Jose F.; Pastorino, Laura; Ruggiero, Carmelina; Nosi, Daniele; Raiteri, Roberto

2010-01-01

The transforming growth factor β1 (TGF-β1) is a human cytokine which has been demonstrated to modulate cell surface integrin repertoire. In this work integrin expression in response to TGF-β1 stimulation has been investigated on the surface of human osteoblast-like cells. We used atomic force microscopy (AFM) and confocal laser scanning microscopy to assess integrin expression and to evaluate their distribution over the dorsal side of the plasma membrane. AFM probes have been covalently functionalised with monoclonal antibodies specific to the β1 integrin subunit. Force curves have been collected in order to obtain maps of the interaction between the immobilized antibody and the respective cell membrane receptors. Adhesion peaks have been automatically detected by means of an ad hoc developed data analysis software. The specificity of the detected interactions has been assessed by adding free antibody in the solution and monitoring the dramatic decrease in the recorded interactions. In addition, the effect of TGF-β1 treatment on both the fluorescence signal and the adhesion events has been tested. The level of expression of the β1 integrin subunit was enhanced by TGF-β1. As a further analysis, the adhesion force of the single living cells to the substrate was measured by laterally pushing the cell with the AFM tip and measuring the force necessary to displace it. The treatment with TGF-β1 resulted in a decrease of the cell/substrate adhesion force. Results obtained by AFM have been validated by confocal laser scanning microscopy thus demonstrating the high potential of the AFM technique for the investigation of cell surface receptors distribution and trafficking at the nanoscale.

Investigation of integrin expression on the surface of osteoblast-like cells by atomic force microscopy

Energy Technology Data Exchange (ETDEWEB)

Caneva Soumetz, Federico [Department of Communication, Computer and System Sciences, University of Genova, Via Opera Pia, 13-16145 Genova (Italy); Saenz, Jose F. [Biophysical and Electronic Engineering Department, University of Genova, Via All' Opera Pia 11a, 16145 Genova (Italy); Pastorino, Laura; Ruggiero, Carmelina [Department of Communication, Computer and System Sciences, University of Genova, Via Opera Pia, 13-16145 Genova (Italy); Nosi, Daniele [Department of Anatomy, Histology and Forensic Medicine, Bio-photonic Laboratory, University of Florence, viale Morgagni, 85 Firenze, CAP 50134 Florence (Italy); Raiteri, Roberto, E-mail: rr@unige.it [Biophysical and Electronic Engineering Department, University of Genova, Via All' Opera Pia 11a, 16145 Genova (Italy)

2010-03-15

The transforming growth factor {beta}1 (TGF-{beta}1) is a human cytokine which has been demonstrated to modulate cell surface integrin repertoire. In this work integrin expression in response to TGF-{beta}1 stimulation has been investigated on the surface of human osteoblast-like cells. We used atomic force microscopy (AFM) and confocal laser scanning microscopy to assess integrin expression and to evaluate their distribution over the dorsal side of the plasma membrane. AFM probes have been covalently functionalised with monoclonal antibodies specific to the {beta}1 integrin subunit. Force curves have been collected in order to obtain maps of the interaction between the immobilized antibody and the respective cell membrane receptors. Adhesion peaks have been automatically detected by means of an ad hoc developed data analysis software. The specificity of the detected interactions has been assessed by adding free antibody in the solution and monitoring the dramatic decrease in the recorded interactions. In addition, the effect of TGF-{beta}1 treatment on both the fluorescence signal and the adhesion events has been tested. The level of expression of the {beta}1 integrin subunit was enhanced by TGF-{beta}1. As a further analysis, the adhesion force of the single living cells to the substrate was measured by laterally pushing the cell with the AFM tip and measuring the force necessary to displace it. The treatment with TGF-{beta}1 resulted in a decrease of the cell/substrate adhesion force. Results obtained by AFM have been validated by confocal laser scanning microscopy thus demonstrating the high potential of the AFM technique for the investigation of cell surface receptors distribution and trafficking at the nanoscale.

Contact behavior analysis of elastomeric x-ring under uniform squeeze rate and internal pressure before and after forcing-out using the photoelastic experimental hybrid method

Energy Technology Data Exchange (ETDEWEB)

Bernard, Alunda Ouma [Dedan Kimathi University of Technology, Nyeri (Kenya); Hawong, Jai Sug; Dong, Bai [Yeungnam University, Gyeongsan (Korea, Republic of); Shin, Dong Chul [Koje College, Geoje (Korea, Republic of)

2015-05-15

Many different types of elastomeric rings have been developed to suit various needs in industry. The X-ring was introduced as a result of the limitations of O-rings that twist, especially during dynamic application. A better understanding of the behavior and the stress distribution of the X-ring under a uniform squeeze rate and internal pressure is needed. We analyzed the contact stresses and internal stresses developed in an X-ring before and after forcing-out by using the photoelastic experimental hybrid method, ascertained the packing ability of an X-ring, and studied the failure criterion of an X-ring under uniform squeeze rate and internal pressure. Forcing-out in the X-ring occurred when the internal pressure was 3.92 MPa. After forcing-out, at an internal pressure of 5.88 MPa, the two lobes on the upper contact surface merged one contact side of the upper side immensely. Even after extrusion of the X-ring, the X-ring can be used to effectively contain the fluid. This is because the effects of extrusion on the X-ring affected the stress distribution of only two lobes close to the assembly gap and the two lobes are merge into one lobe. In addition, our experimental results show that the maximum shear failure criterion is suitable for the prediction of failure in X-ring seals.

Investigations on cooling with forced flow of He II

International Nuclear Information System (INIS)

Srinivasan, R.; Hofmann, A.

1985-01-01

Investigations on heat transfer to flowing subcooled He II at a pressure of 7 bar have been carried out. The value of the conductivity function, f(T), at a temperature greater than Tsub(max), drops rapidly with increasing pressure. Below Tsub(max) the change in f(T) with pressure is less drastic. The Gorter-Mellink constant Asub(GM), increases linearly with pressure in the range 1.5-2 K and its pressure coefficient at 1 bar is 0.038+-0.01 per bar, independent of temperature. The temperature distribution in the test section with and without flow is adequately described by the one-dimensional model discussed in Part 1. It is concluded that for heat transfer to He II in forced flow there is no advantage in working at pressures > 1 bar. (author)

Experimental Investigation of Unsteady Aerodynamic Forces on Airfoil in Harmonic Translatory Motion

DEFF Research Database (Denmark)

Gaunaa, Mac; Sørensen, Jens Nørkær

2003-01-01

The present paper describes the main results from an experimental investigation of the unsteady aerodynamic forces on a NACA 0015 airfoil subject to 1-degree-of-freedom (DOF) harmonic translatory motion. The focus of the experimental investigations was to determine the factors that influence...... maximum lift for both stationary and moving airfoil configurations. The mean as well as the dynamic characteristics of the different stall levels were found to differ from each other. An investigation of the negative aerodynamically damped cases showed that the damping decrease as the reduced frequency...... is decreased. Comparison between the experimental data, 2D Navier-Stokes computations and two commonly used dynamic stall models reveal that all models failed to reproduce the dynamic characteristics of the flow for incidences above maximum lift, however the Navier-Stokes computations generally captured...

Proceedings of the IRI task force activity 2000

International Nuclear Information System (INIS)

Radicella, Sandro M.

2001-05-01

This internal report of the International Center for Theoretical Physics (ICTP) contains presentations delivered during the International Reference Ionosphere Task Force Activity 2000 which took place at the Abdus Salam ICTP during July 2000. The 2000 Task Force Activity is the seventh successful encounter of specialists organized by the URSI-COSPAR IRI Working Group and the Aeronomy and Radiopropagation Laboratory of the ICTP of Trieste, Italy. The main topic of this task force activity was the modeling of the topside ionosphere and the development of strategies for modeling of ionospheric variability

EXPERIMENTAL INVESTIGATION OF THE IMPACT OF FLIGHT SPEED ON DRAG FORCE IN THE AUTOGYRO MODEL

OpenAIRE

Zbigniew Czyż; Paweł Magryta; Marcin Szlachetka

2015-01-01

The paper presents the experimental investigation of the impact of velocity on drag force in the autogyro model. One of the methods which simulate motion of the flying object consists of using a wind tunnel. In this case, test object is stationary and the motion of air is forced by e.g. a special fan. The costs related with renting and the wind tunnel service are still very high. In this paper, the motion of the autogyro with respect to the air, was produced by fixing this model with scale to...

Investigation of the heparin-thrombin interaction by dynamic force spectroscopy.

Science.gov (United States)

Wang, Congzhou; Jin, Yingzi; Desai, Umesh R; Yadavalli, Vamsi K

2015-06-01

The interaction between heparin and thrombin is a vital step in the blood (anti)coagulation process. Unraveling the molecular basis of the interactions is therefore extremely important in understanding the mechanisms of this complex biological process. In this study, we use a combination of an efficient thiolation chemistry of heparin, a self-assembled monolayer-based single molecule platform, and a dynamic force spectroscopy to provide new insights into the heparin-thrombin interaction from an energy viewpoint at the molecular scale. Well-separated single molecules of heparin covalently attached to mixed self-assembled monolayers are demonstrated, whereby interaction forces with thrombin can be measured via atomic force microscopy-based spectroscopy. Further these interactions are studied at different loading rates and salt concentrations to directly obtain kinetic parameters. An increase in the loading rate shows a higher interaction force between the heparin and thrombin, which can be directly linked to the kinetic dissociation rate constant (koff). The stability of the heparin/thrombin complex decreased with increasing NaCl concentration such that the off-rate was found to be driven primarily by non-ionic forces. These results contribute to understanding the role of specific and nonspecific forces that drive heparin-thrombin interactions under applied force or flow conditions. Copyright © 2015 Elsevier B.V. All rights reserved.

Malaysia and forced migration

Directory of Open Access Journals (Sweden)

Arzura Idris

2012-06-01

Full Text Available This paper analyzes the phenomenon of “forced migration” in Malaysia. It examines the nature of forced migration, the challenges faced by Malaysia, the policy responses and their impact on the country and upon the forced migrants. It considers forced migration as an event hosting multifaceted issues related and relevant to forced migrants and suggests that Malaysia has been preoccupied with the issue of forced migration movements. This is largely seen in various responses invoked from Malaysia due to “south-south forced migration movements.” These responses are, however, inadequate in terms of commitment to the international refugee regime. While Malaysia did respond to economic and migration challenges, the paper asserts that such efforts are futile if she ignores issues critical to forced migrants.

Investigating biomolecular recognition at the cell surface using atomic force microscopy.

Science.gov (United States)

Wang, Congzhou; Yadavalli, Vamsi K

2014-05-01

Probing the interaction forces that drive biomolecular recognition on cell surfaces is essential for understanding diverse biological processes. Force spectroscopy has been a widely used dynamic analytical technique, allowing measurement of such interactions at the molecular and cellular level. The capabilities of working under near physiological environments, combined with excellent force and lateral resolution make atomic force microscopy (AFM)-based force spectroscopy a powerful approach to measure biomolecular interaction forces not only on non-biological substrates, but also on soft, dynamic cell surfaces. Over the last few years, AFM-based force spectroscopy has provided biophysical insight into how biomolecules on cell surfaces interact with each other and induce relevant biological processes. In this review, we focus on describing the technique of force spectroscopy using the AFM, specifically in the context of probing cell surfaces. We summarize recent progress in understanding the recognition and interactions between macromolecules that may be found at cell surfaces from a force spectroscopy perspective. We further discuss the challenges and future prospects of the application of this versatile technique. Copyright © 2014 Elsevier Ltd. All rights reserved.

Stochastically-forced Decadal Variability in Australian Rainfall

Science.gov (United States)

Taschetto, A.

2015-12-01

Iconic Australian dry and wet periods were driven by anomalous conditions in the tropical oceans, such as the worst short-term drought in the southeast in 1982 associated with the strong El Niño and the widespread "Big Wet" in 1974 linked with a La Niña event. The association with oceanic conditions makes droughts predictable to some extent. However, prediction can be difficult when there is no clear external forcing such as El Niños. Can dry spells be triggered and maintained with no ocean memory? In this study, we investigate the potential role of internal multi-century atmospheric variability in controlling the frequency, duration and intensity of long-term dry and wet spells over Australia. Two multi-century-scale simulations were performed with the NCAR CESM: (1) a fully-coupled simulation (CPLD) and (2) an atmospheric simulation forced by a seasonal SST climatology derived from the coupled experiment (ACGM). Results reveal that droughts and wet spells can indeed be generated by internal variability of the atmosphere. Those internally generated events are less severe than those forced by oceanic variability, however the duration of dry and wet spells longer than 3 years is comparable with and without the ocean memory. Large-scale ocean modes of variability seem to play an important role in producing continental-scale rainfall impacts over Australia. While the Pacific Decadal Oscillation plays an important role in generating droughts in the fully coupled model, perturbations of monsoonal winds seem to be the main trigger of dry spells in the AGCM case. Droughts in the mid-latitude regions such as Tasmania can be driven by perturbations in the Southern Annular Mode, not necessarily linked to oceanic conditions even in the fully-coupled model. The mechanisms behind internally-driven mega-droughts and mega-wets will be discussed.

An Evolution in Research Practice for Investigating International Business Relationships

OpenAIRE

Anne HAMPTON; James ROWELL

2013-01-01

The purpose of this paper is to discuss the development and rationale of research methodology for a specific topic of research. The topic in question is an investigation into international business relationships, a complex subject and one that is very topical in the growing world of international business. It is intended to examine the logical development of research practice in our study and to show the changing thought processes and justifications we have made over a period of time. It is h...

Painleve analysis for a forced Korteveg-de Vries equation arisen in fluid dynamics of internal solitary waves

Directory of Open Access Journals (Sweden)

Zhang Sheng

2015-01-01

Full Text Available In this paper, Painleve analysis is used to test the Painleve integrability of a forced variable-coefficient extended Korteveg-de Vries equation which can describe the weakly-non-linear long internal solitary waves in the fluid with continuous stratification on density. The obtained results show that the equation is integrable under certain conditions. By virtue of the truncated Painleve expansion, a pair of new exact solutions to the equation is obtained.

At the Fulcrum of Air Force Identity: Balancing the Internal and External Pressures of Image and Culture

Science.gov (United States)

2014-01-01

internally oriented understanding (labeled culture).10 Their model is an organizational abstraction of George Mead’s 1934 charac- terization of...fundamental shift in the societal structure of the day. Norman Cantor indicates that “the main social consequence of the Black Death was not the...FILE APPROACH TO THE US AIR FORCE IDENTITY 50 In a move eerily reminiscent of George Orwell’s “Ministry of Truth,” Mose- ley declared, “Our new

Prosthetic finger phalanges with lifelike skin compliance for low-force social touching interactions

Directory of Open Access Journals (Sweden)

Ge Shuzhi

2011-03-01

Full Text Available Abstract Background Prosthetic arms and hands that can be controlled by the user's electromyography (EMG signals are emerging. Eventually, these advanced prosthetic devices will be expected to touch and be touched by other people. As realistic as they may look, the currently available prosthetic hands have physical properties that are still far from the characteristics of human skins because they are much stiffer. In this paper, different configurations of synthetic finger phalanges have been investigated for their skin compliance behaviour and have been compared with the phalanges of the human fingers and a phalanx from a commercially available prosthetic hand. Methods Handshake tests were performed to identify which areas on the human hand experience high contact forces. After these areas were determined, experiments were done on selected areas using an indenting probe to obtain the force-displacement curves. Finite element simulations were used to compare the force-displacement results of the synthetic finger phalanx designs with that of the experimental results from the human and prosthetic finger phalanges. The simulation models were used to investigate the effects of (a varying the internal topology of the finger phalanx and (b varying different materials for the internal and external layers. Results and Conclusions During handshake, the high magnitudes of contact forces were observed at the areas where the full grasping enclosure of the other person's hand can be achieved. From these areas, the middle phalanges of the (a little, (b ring, and (c middle fingers were selected. The indentation experiments on these areas showed that a 2 N force corresponds to skin tissue displacements of more than 2 mm. The results from the simulation model show that introducing an open pocket with 2 mm height on the internal structure of synthetic finger phalanges increased the skin compliance of the silicone material to 235% and the polyurethane material to

Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Diagnostic Task Force Criteria Impact of New Task Force Criteria

NARCIS (Netherlands)

Cox, Moniek G. P. J.; van der Smagt, Jasper J.; Noorman, Maartje; Wiesfeld, Ans C.; Volders, Paul G. A.; van Langen, Irene M.; Atsma, Douwe E.; Dooijes, Dennis; Houweling, Arjan C.; Loh, Peter; Jordaens, Luc; Arens, Yvonne; Cramer, Maarten J.; Doevendans, Pieter A.; van Tintelen, Peter; Wilde, Arthur A. M.; Hauer, Richard N. W.

Background-Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) Diagnostic Task Force Criteria (TFC) proposed in 1994 are highly specific but lack sensitivity. A new international task force modified criteria to improve diagnostic yield. A comparison of diagnosis by 1994 TFC versus

Theoretical investigation of the distance dependence of capillary and van der Waals forces in scanning force microscopy

International Nuclear Information System (INIS)

Stifter, Thomas; Marti, Othmar; Bhushan, Bharat

2000-01-01

The capillary and van der Waals forces between a tip and a plane in a scanning force microscope (SFM) are calculated. The forces are calculated for a fixed distance of tip and sample, as well as during retracting of the tip from the sample surface. The exact geometric shape of the meniscus is considered, with the boundary condition of fixed liquid volume during retraction. The starting volume is given by the operating and environmental conditions (surface tension, humidity, and tip geometry) at the point of lowest distance between tip and surface. The influence of the different parameters, namely, humidity, tip geometry, tip-sample starting distance, surface tension, and contact angles are studied. For each force curve also the geometric shape of the meniscus is calculated. The capillary forces are compared with van der Waals forces to understand their relative importance in various operating conditions. In addition to application in SFM, this analysis is useful in the design of surface roughness in microdevices for low adhesion in operating environments

Force field inside the void in complex plasmas under microgravity conditions

International Nuclear Information System (INIS)

Kretschmer, M.; Khrapak, S.A.; Zhdanov, S.K.; Thomas, H.M.; Morfill, G.E.; Fortov, V.E.; Lipaev, A.M.; Molotkov, V.I.; Ivanov, A.I.; Turin, M.V.

2005-01-01

Observations of complex plasmas under microgravity conditions onboard the International Space Station performed with the Plasma-Kristall experiment-Nefedov facility are reported. A weak instability of the boundary between the central void (region free of microparticles) and the microparticle cloud is observed at low gas pressures. The instability leads to periodic injections of a relatively small number of particles into the void region (by analogy this effect is called the 'trampoline effect'). The trajectories of injected particles are analyzed providing information on the force field inside the void. The experimental results are compared with theory which assumes that the most important forces inside the void are the electric and the ion drag forces. Good agreement is found clearly indicating that under conditions investigated the void formation is caused by the ion drag force

Investigating single molecule adhesion by atomic force spectroscopy.

Science.gov (United States)

Stetter, Frank W S; Kienle, Sandra; Krysiak, Stefanie; Hugel, Thorsten

2015-02-27

Atomic force spectroscopy is an ideal tool to study molecules at surfaces and interfaces. An experimental protocol to couple a large variety of single molecules covalently onto an AFM tip is presented. At the same time the AFM tip is passivated to prevent unspecific interactions between the tip and the substrate, which is a prerequisite to study single molecules attached to the AFM tip. Analyses to determine the adhesion force, the adhesion length, and the free energy of these molecules on solid surfaces and bio-interfaces are shortly presented and external references for further reading are provided. Example molecules are the poly(amino acid) polytyrosine, the graft polymer PI-g-PS and the phospholipid POPE (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine). These molecules are desorbed from different surfaces like CH3-SAMs, hydrogen terminated diamond and supported lipid bilayers under various solvent conditions. Finally, the advantages of force spectroscopic single molecule experiments are discussed including means to decide if truly a single molecule has been studied in the experiment.

A compact internal drum test rig for measurements of rolling contact forces between a single tread block and a substrate

NARCIS (Netherlands)

Lundberg, O.E.; Kari, L.; Lopez Arteaga, I.

2017-01-01

A novel test rig design is presented which enables detailed studies of the three force components generated in the impact and release phase of rolling contact between a tyre tread block and a substrate. The design of the compact internal drum test rig provides realistic impact and release angles for

Morphology of compressed dipalmitoyl phosphatidylcholine monolayers investigated by atomic force microscopy

International Nuclear Information System (INIS)

Yang, Y.-P.; Tsay, R.-Y.

2007-01-01

The effectiveness of a substitute of natural lung surfactants on replacement therapy strongly depends on the stability of the monolayer of those substitute molecules. An atomic force microscope is utilized to investigate the microstructure of the films of the major components of natural lung surfactants, dipalmitoyl phosphatidylcholine-DPPC, which are transferred to mica substrates by the Langmuir-Blodgett film technique. A concave deformation structure was first observed for DPPC in solid phase. The depth of the concave domain was about 6 nm and was remarkably uniform. For a collapsed DPPC monolayer, the surface film consists of a granular convex multilayer structure and a disc-like concave structure. Dynamic cyclic compression-expansion experiments indicate that the formation of the concave domain is a reversible process while the process for convex multilayer formation is irreversible. This gives direct evidence that convex grain is the collapsed structure of DPPC monolayer and the concave shallow disc corresponds to the elastic deformation of a DPPC solid film. Results of atomic force microscopy indicate that the nucleation and growth model instead of the fracture model can better describe the collapse behavior of a DPPC monolayer

[Environmental investigation of ground water contamination at Wright-Patterson Air Force Base, Ohio]. Volume 5, Field Investigation report

Energy Technology Data Exchange (ETDEWEB)

1992-03-01

An environmental investigation of ground water conditions has been undertaken at Wright-Patterson Air Force Base (WPAFB), Ohio to obtain data to assist in the evaluation of a potential removal action to prevent, to the extent practicable, migration of the contaminated ground water across Base boundaries. Field investigations were limited to the central section of the southwestern boundary of Area C and the Springfield Pike boundary of Area B. Further, the study was limited to a maximum depth of 150 feet below grade. Three primary activities of the field investigation were: (1) installation of 22 monitoring wells, (2) collection and analysis of ground water from 71 locations, (3) measurement of ground water elevations at 69 locations. Volatile organic compounds including trichloroethylene, perchloroethylene, and/or vinyl chloride were detected in concentrations exceeding Maximum Contaminant Levels (MCL) at three locations within the Area C investigation area. Ground water at the Springfield Pike boundary of Area B occurs in two primary units, separated by a thicker-than-expected clay layers. One well within Area B was determined to exceed the MCL for trichloroethylene.

Internally displaced "victims of armed conflict" in Colombia: the trajectory and trauma signature of forced migration.

Science.gov (United States)

Shultz, James M; Garfin, Dana Rose; Espinel, Zelde; Araya, Ricardo; Oquendo, Maria A; Wainberg, Milton L; Chaskel, Roberto; Gaviria, Silvia L; Ordóñez, Anna E; Espinola, Maria; Wilson, Fiona E; Muñoz García, Natalia; Gómez Ceballos, Angela Milena; Garcia-Barcena, Yanira; Verdeli, Helen; Neria, Yuval

2014-10-01

While conflict-induced forced migration is a global phenomenon, the situation in Colombia, South America, is distinctive. Colombia has ranked either first or second in the number of internally displaced persons for 10 years, a consequence of decades of armed conflict compounded by high prevalence of drug trafficking. The displacement trajectory for displaced persons in Colombia proceeds through a sequence of stages: (1) pre-expulsion threats and vulnerability, (2) expulsion, (3) migration, (4) initial adaptation to relocation, (5) protracted resettlement (the end point for most forced migrants), and, rarely, (6) return to the community of origin. Trauma signature analysis, an evidence-based method that elucidates the physical and psychological consequences associated with exposures to harm and loss during disasters and complex emergencies, was used to identify the psychological risk factors and potentially traumatic events experienced by conflict-displaced persons in Colombia, stratified across the phases of displacement. Trauma and loss are experienced differentially throughout the pathway of displacement.

The International Society for Bipolar Disorders (ISBD) Task Force Report on Antidepressant Use in Bipolar Disorders

Science.gov (United States)

Pacchiarotti, Isabella; Bond, David J.; Baldessarini, Ross J.; Nolen, Willem A.; Grunze, Heinz; Licht, Rasmus W.; Post, Robert M.; Berk, Michael; Goodwin, Guy M.; Sachs, Gary S.; Tondo, Leonardo; Findling, Robert L.; Youngstrom, Eric A.; Tohen, Mauricio; Undurraga, Juan; González-Pinto, Ana; Goldberg, Joseph F.; Yildiz, Ayşegül; Altshuler, Lori L.; Calabrese, Joseph R.; Mitchell, Philip B.; Thase, Michael E.; Koukopoulos, Athanasios; Colom, Francesc; Frye, Mark A.; Malhi, Gin S.; Fountoulakis, Konstantinos N.; Vázquez, Gustavo; Perlis, Roy H.; Ketter, Terence A.; Cassidy, Frederick; Akiskal, Hagop; Azorin, Jean-Michel; Valentí, Marc; Mazzei, Diego Hidalgo; Lafer, Beny; Kato, Tadafumi; Mazzarini, Lorenzo; Martínez-Aran, Anabel; Parker, Gordon; Souery, Daniel; Özerdem, Ayşegül; McElroy, Susan L.; Girardi, Paolo; Bauer, Michael; Yatham, Lakshmi N.; Zarate, Carlos A.; Nierenberg, Andrew A.; Birmaher, Boris; Kanba, Shigenobu; El-Mallakh, Rif S.; Serretti, Alessandro; Rihmer, Zoltan; Young, Allan H.; Kotzalidis, Georgios D.; MacQueen, Glenda M.; Bowden, Charles L.; Ghaemi, S. Nassir; Lopez-Jaramillo, Carlos; Rybakowski, Janusz; Ha, Kyooseob; Perugi, Giulio; Kasper, Siegfried; Amsterdam, Jay D.; Hirschfeld, Robert M.; Kapczinski, Flávio; Vieta, Eduard

2014-01-01

Objective The risk-benefit profile of antidepressant medications in bipolar disorder is controversial. When conclusive evidence is lacking, expert consensus can guide treatment decisions. The International Society for Bipolar Disorders (ISBD) convened a task force to seek consensus recommendations on the use of antidepressants in bipolar disorders. Method An expert task force iteratively developed consensus through serial consensus-based revisions using the Delphi method. Initial survey items were based on systematic review of the literature. Subsequent surveys included new or reworded items and items that needed to be rerated. This process resulted in the final ISBD Task Force clinical recommendations on antidepressant use in bipolar disorder. Results There is striking incongruity between the wide use of and the weak evidence base for the efficacy and safety of antidepressant drugs in bipolar disorder. Few well-designed, long-term trials of prophylactic benefits have been conducted, and there is insufficient evidence for treatment benefits with antidepressants combined with mood stabilizers. A major concern is the risk for mood switch to hypomania, mania, and mixed states. Integrating the evidence and the experience of the task force members, a consensus was reached on 12 statements on the use of antidepressants in bipolar disorder. Conclusions Because of limited data, the task force could not make broad statements endorsing antidepressant use but acknowledged that individual bipolar patients may benefit from antidepressants. Regarding safety, serotonin reuptake inhibitors and bupropion may have lower rates of manic switch than tricyclic and tetracyclic antidepressants and norepinephrine-serotonin reuptake inhibitors. The frequency and severity of antidepressant-associated mood elevations appear to be greater in bipolar I than bipolar II disorder. Hence, in bipolar I patients antidepressants should be prescribed only as an adjunct to mood-stabilizing medications

75 FR 15739 - International Business Machines Corporation: Armonk, NY; Notice of Termination of Investigation

Science.gov (United States)

2010-03-30

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-70,580] International Business Machines Corporation: Armonk, NY; Notice of Termination of Investigation Pursuant to Section 223 of the Trade Act of 1974, as amended, an investigation was initiated in response to a petition filed on May 21, 2009 on behalf of workers of International...

'SOSORT consensus paper on brace action: TLSO biomechanics of correction (investigating the rationale for force vector selection'

Directory of Open Access Journals (Sweden)

Maruyama T

2006-07-01

Full Text Available Abstract Background The effectiveness of orthotic treatment continues to be controversial in international medical literature due to differences in the reported results and conclusions of various studies. Heterogeneity of the samples has been suggested as a reason for conflicting results. Besides the obvious theoretical differences between the brace concepts, the variability in the technical factors can also explain the contradictory results between same brace types. This paper will investigate the degree of variability among responses of scoliosis specialists from the Brace Study Ground of the International Society on Scoliosis Orthopedic and Rehabilitation Treatment SOSORT. Ultimately, this information could be a foundation for establishing a consensus and framework for future prospective controlled studies. Methods A preliminary questionnaire on the topic of 'brace action' relative to the theory of three-dimensional scoliosis correction and brace treatment was developed and circulated to specialists interested in the conservative treatment of adolescent idiopathic scoliosis. A particular case was presented (main thoracic curve with minor lumbar. Several key points emerged and were used to develop a second questionnaire which was discussed and full filed after the SOSORT consensus meeting (Milano, Italy, January 2005. Results Twenty-one questionnaires were completed. The Chêneau brace was the most frequently recommended. The importance of the three point system mechanism was stressed. Options about proper pad placement on the thoracic convexity were divided 50% for the pad reaching or involving the apical vertebra and 50% for the pad acting caudal to the apical vertebra. There was agreement about the direction of the vector force, 85% selecting a 'dorso lateral to ventro medial' direction but about the shape of the pad to produce such a force. Principles related to three-dimensional correction achieved high consensus (80%–85%, but suggested

A report on older-age bipolar disorder from the International Society for Bipolar Disorders Task Force

DEFF Research Database (Denmark)

Sajatovic, Martha; Strejilevich, Sergio A; Gildengers, Ariel G

2015-01-01

, and shed light on issues of relevance to BD research across the lifespan. Although there is still a dearth of research and health efforts focused on older adults with BD, emerging data have brought some answers, innovative questions, and novel perspectives related to the notion of late onset, medical......OBJECTIVES: In the coming generation, older adults with bipolar disorder (BD) will increase in absolute numbers as well as proportion of the general population. This is the first report of the International Society for Bipolar Disorder (ISBD) Task Force on Older-Age Bipolar Disorder (OABD). METHODS...

Hydrostatic force sensor

International Nuclear Information System (INIS)

Evans, M.S.; Stoughton, R.S.; Kazerooni, H.

1994-08-01

This paper presents a theoretical and experimental investigation of a new kind of force sensor which detects forces by measuring an induced pressure change in a material of large Poisson's ratio. In this investigation we develop mathematical expressions for the sensor's sensitivity and bandwidth, and show that its sensitivity can be much larger and its bandwidth is usually smaller than those of existing strain-gage-type sensors. This force sensor is well-suited for measuring large but slowly varying forces. It can be installed in a space smaller than that required by existing sensors

Monsoonal Responses to External Forcings over the Past Millennium: A Model Study (Invited)

Science.gov (United States)

Liu, J.; Wang, B.

2009-12-01

The climate variations related to Global Monsoon (GM) and East Asian summer monsoon (EASM) rainfall over the past 1000 years were investigated by analysis of a pair of millennium simulations with the coupled climate model named ECHO-G. The free run was generated using fixed external (annual cycle) forcing, while the forced run was obtained using time-varying solar irradiance variability, greenhouse gases (CO2 and CH4) concentration and estimated radiative effect of volcanic aerosols. The model results indicate that the centennial-millennial variation of the GM and EASM is essentially a forced response to the external radiative forcings (insolation, volcanic aerosols, and greenhouse gases). The GM strength responds more directly to the effective solar forcing (insolation plus radiative effect of the volcanoes) when compared to responses of the global mean surface temperature on centennial timescale. The simulated GM precipitation in the forced run exhibits a significant quasi-bi-centennial oscillation. Weak GM precipitation was simulated during the Little Ice Age (1450-1850) with three weakest periods concurring with the Spörer, Maunder, and Dalton Minimum of solar activity. Conversely, strong GM was simulated during the model Medieval Warm Period (ca. 1030-1240). Before the industrial period, the natural variation in effective solar forcing reinforces the thermal contrasts both between the ocean and continent and between the northern and southern hemispheres, resulting in millennium-scale variation and the quasi-bi-centennial oscillation of the GM. The prominent upward trend in the GM precipitation occurring in the last century and the remarkably strengthening of the global monsoon in the period of 1961-1990 appear unprecedented and owed possibly in part to the increase of atmospheric carbon dioxide concentration. The EASM has the largest meridional extent (5oN-55oN) among all the regional monsoons on globe. Thus, the EASM provides an unique opportunity for

A review of a method for dynamic load distribution, dynamical modeling, and explicit internal force control when two manipulators mutually lift and transport a rigid body object

International Nuclear Information System (INIS)

Unseren, M.A.

1997-01-01

The paper reviews a method for modeling and controlling two serial link manipulators which mutually lift and transport a rigid body object in a three dimensional workspace. A new vector variable is introduced which parameterizes the internal contact force controlled degrees of freedom. A technique for dynamically distributing the payload between the manipulators is suggested which yields a family of solutions for the contact forces and torques the manipulators impart to the object. A set of rigid body kinematic constraints which restrict the values of the joint velocities of both manipulators is derived. A rigid body dynamical model for the closed chain system is first developed in the joint space. The model is obtained by generalizing the previous methods for deriving the model. The joint velocity and acceleration variables in the model are expressed in terms of independent pseudovariables. The pseudospace model is transformed to obtain reduced order equations of motion and a separate set of equations governing the internal components of the contact forces and torques. A theoretic control architecture is suggested which explicitly decouples the two sets of equations comprising the model. The controller enables the designer to develop independent, non-interacting control laws for the position control and internal force control of the system

A review of a method for dynamic load distribution, dynamical modeling, and explicit internal force control when two manipulators mutually lift and transport a rigid body object

Energy Technology Data Exchange (ETDEWEB)

Unseren, M.A.

1997-04-20

The paper reviews a method for modeling and controlling two serial link manipulators which mutually lift and transport a rigid body object in a three dimensional workspace. A new vector variable is introduced which parameterizes the internal contact force controlled degrees of freedom. A technique for dynamically distributing the payload between the manipulators is suggested which yields a family of solutions for the contact forces and torques the manipulators impart to the object. A set of rigid body kinematic constraints which restrict the values of the joint velocities of both manipulators is derived. A rigid body dynamical model for the closed chain system is first developed in the joint space. The model is obtained by generalizing the previous methods for deriving the model. The joint velocity and acceleration variables in the model are expressed in terms of independent pseudovariables. The pseudospace model is transformed to obtain reduced order equations of motion and a separate set of equations governing the internal components of the contact forces and torques. A theoretic control architecture is suggested which explicitly decouples the two sets of equations comprising the model. The controller enables the designer to develop independent, non-interacting control laws for the position control and internal force control of the system.

Report of a workshop on nuclear forces and nonproliferation Woodrow Wilson international center for scholars, Washington, DC October 28, 2010

Energy Technology Data Exchange (ETDEWEB)

Pilat, Joseph F [Los Alamos National Laboratory

2010-12-08

A workshop sponsored by the Los Alamos National Laboratory in cooperation with the Woodrow Wilson International Center for Scholars was held at the Wilson Center in Washington, DC, on October 28, 2010. The workshop addressed evolving nuclear forces and their impacts on nonproliferation in the context of the new strategic environment, the Obama Administration's Nuclear Posture Review and the 2010 NPT Review Conference. The discussions reflected the importance of the NPR for defining the role of US nuclear forces in dealing with 21st century threats and providing guidance for National Nuclear Security Administration (NNSA) and Department of Defense (DoD) programs and, for many but not all participants, highlighted its role in the successful outcome of the NPT RevCon. There was widespread support for the NPR and its role in developing the foundations for a sustainable nuclear-weapon program that addresses nuclear weapons, infrastructure and expertise in the broader nonproliferation, disarmament and international security contexts. However, some participants raised concerns about its implementation and its long-term effectiveness and sustainability.

Pore Formation and Mobility Investigation (PFMI): Concept, Hardware Development, and Initial Analysis of Experiments Conducted Aboard the International Space Station

Science.gov (United States)

Grugel, Richard N.

2003-01-01

Porosity in the form of "bubbles and pipes" can occur during controlled directional solidification processing of metal alloys. This is a consequence that 1) precludes obtaining any meaningful scientific results and 2) is detrimental to desired material properties. Unfortunately, several Microgravity experiments have been compromised by porosity. The intent of the PFMl investigation is to conduct a systematic effort directed towards understanding porosity formation and mobility during controlled directional solidification (DS) in a microgravity environment. PFMl uses a pure transparent material, succinonitrile (SCN), as well as SCN "alloyed" with water, in conjunction with a translating temperature gradient stage so that direct observation and recording of pore generation and mobility can be made. PFMl is investigating the role of thermocapillary forces and temperature gradients in affecting bubble dynamics as well as other solidification processes in a microgravity environment. This presentation will cover the concept, hardware development, operations, and the initial results from experiments conducted aboard the International Space Station.

Investigation of force, contact area, and dwell time in finger-tapping tasks on membrane touch interface.

Science.gov (United States)

Liu, Na; Yu, Ruifeng

2018-06-01

This study aimed to determine the touch characteristics during tapping tasks on membrane touch interface and investigate the effects of posture and gender on touch characteristics variables. One hundred participants tapped digits displayed on a membrane touch interface on sitting and standing positions using all fingers of the dominant hand. Touch characteristics measures included average force, contact area, and dwell time. Across fingers and postures, males exerted larger force and contact area than females, but similar dwell time. Across genders and postures, thumb exerted the largest force and the force of the other four fingers showed no significant difference. The contact area of the thumb was the largest, whereas that of the little finger was the smallest; the dwell time of the thumb was the longest, whereas that of the middle finger was the shortest. Relationships among finger sizes, gender, posture and touch characteristics were proposed. The findings helped direct membrane touch interface design for digital and numerical control products from hardware and software perspectives. Practitioner Summary: This study measured force, contact area, and dwell time in tapping tasks on membrane touch interface and examined effects of gender and posture on force, contact area, and dwell time. The findings will direct membrane touch interface design for digital and numerical control products from hardware and software perspectives.

Corticomuscular synchronization with small and large dynamic force output

Science.gov (United States)

Andrykiewicz, Agnieszka; Patino, Luis; Naranjo, Jose Raul; Witte, Matthias; Hepp-Reymond, Marie-Claude; Kristeva, Rumyana

2007-01-01

in the low force range investigated. We suggest that gamma CMC is rather associated with the internal state of the sensorimotor system as supported by the unchanged relative error between both dynamic conditions. PMID:18042289

Corticomuscular synchronization with small and large dynamic force output

Directory of Open Access Journals (Sweden)

Witte Matthias

2007-11-01

effect on the gamma CMC in the low force range investigated. We suggest that gamma CMC is rather associated with the internal state of the sensorimotor system as supported by the unchanged relative error between both dynamic conditions.

Determination of Elevator and Rudder Hinge Forces on the Learjet Model 55 Aircraft

Science.gov (United States)

Boroughs, R. R.; Padmanabhan, V.

1983-01-01

The empennage structure on the Learjet 55 aircraft was quite similar to the empennage structure on earlier Learjet models. However, due to an important structural change in the vertical fin along with the new loads environment on the 50 series aircraft, a structural test was required on the vertical fin, but the horizontal tail was substantiated by a comparative analysis with previous tests. NASTRAN analysis was used to investigate empennage deflections, stress levels, and control surface hinge forces. The hinge force calculations were made with the control surfaces in the deflected as well as undeflected configurations. A skin panel buckling analysis was also performed, and the non-linear effects of buckling were simulated in the NASTRAN model to more accurately define internal loads and stress levels. Comparisons were then made between the Model 55 and the Model 35/36 stresses and internal forces to determine which components were qualified by previous tests. Some of the methods and techniques used in this analysis are described.

Experimental investigation of unsteady fluid dynamic forces acting on tube array

International Nuclear Information System (INIS)

Tanaka, Hiroki; Takahara, Shigeru; Tanaka, Mitsutoshi

1981-01-01

It is well-known that the cylinder bundle vibrates in cross flow. Many studies of the vibration have been made, and it has been clarified that the vibration is caused by fluid-elastic vibration coupling to neighboring cylinders. The theory given in this paper considers unsteady fluid dynamic forces to be composed of inertia forces due to added mass of fluid, damping forces of fluid which are in phase to cylinder vibrating velocity, and stiffness forces which are proportional to cylinder displacements. Furthermore, taking account of the influences of neighboring cylinder vibrations, ten kinds of unsteady fluid dynamic forces are considered to act on a cylinder in cylinder bundles. Equations of motion of cylinders were deduced and the critical velocities were calculated with the measured unsteady fluid dynamic forces. Critical velocity tests were also conducted with cylinders which were supported with elastic spars. The calculated critical velocities coincided well with the test results. (author)

Interdisciplinary Perspectives on Special Operations Forces

DEFF Research Database (Denmark)

is the result of a research projec tproviding international interdisciplinary perspectives on special operations forces, based on three main themes: - Leading and organizing for strategic effect - Professional entrepreneurship and self-perceptions in special operations forces - Political and popular perceptions...

SOUTH AFRICA AND THE SADC STAND-BY FORCE

African Journals Online (AJOL)

hennie

Such institutions depict the power relations prevailing at .... ministers responsible for foreign affairs, defence, public security and state security from each ...... 15 Force-to-force ratios measure how big an international force has to be to balance.

International seminar on structural investigations on pulsed neutron sources. Proceedings

International Nuclear Information System (INIS)

Aksenov, V.L.; Balagurov, A.M.; Taran, Yu.V.

1993-01-01

The proceedings of the International seminar on structural investigations using pulsed neutron sources are presented. The seminar is dedicated to the memory of Dr. Yu.M. Ostanevich, a world acknowledged physicist. The problems of structural analysis using pulsed neutron source at the IBR-2 reactor are discussed

78 FR 72714 - Child Labor, Forced Labor, and Forced or Indentured Child Labor in the Production of Goods in...

Science.gov (United States)

2013-12-03

... DEPARTMENT OF LABOR Child Labor, Forced Labor, and Forced or Indentured Child Labor in the... Child Labor AGENCY: The Bureau of International Labor Affairs, United States Department of Labor. ACTION..., 2013, regarding child labor and forced labor in foreign countries. Relevant information will be used by...

Investigation of a double oscillating-fan cooling device using electromagnetic force

International Nuclear Information System (INIS)

Su, Hsien-Chin; Xu, Han Yang

2016-01-01

Highlights: • The characteristics of a double oscillating-fan cooling device using electromagnetic force was investigated. • The driving current can be either DC PWM or AC within 3–12 V. • The comparison between a double blower pair, the model and a synjet were examined. • A 50 mm ∗ 50 mm ∗ 15 mm model can provide the flow rate of 154.89 l/min while consuming 0.65 W. • The flow rate, sound pressure, power consumption and two thermal tests have been done. - Abstract: This study proposes a double oscillating-fan cooling device using electromagnetic force. The device consists of two oscillating-fans. It requires only one electromagnet and two fan sheets with one magnet on each of them. The electromagnet and fan sheets are situated on a base and arranged accordingly. The electromagnetic force generated by the electromagnet can actuate the fan sheets. The main advantage of the device is its simple structure because there is no bearing and motor in the device. The driving current can be either DC PWM (Pulse width modulation) or AC (Alternating current) within 3–12 V so it is compatible with most electronic devices. The dimensions of the proposed model are 50 mm ∗ 50 mm ∗ 15 mm during operation. Concerning flow rate, sound pressure, power consumption and resonant frequency tests, a comparison between the proposed model and different type of cooling devices has been completed. The result shows that the model can provide cooling ability similar to a rotary fan while consuming 40% of the power of the rotary fan. It shows not only a good cooling ability but also a great potential for structural reliability and design flexibility.

An Investigation of Marketing Educators' Approach to Teaching International Marketing in the Introductory Marketing Course.

Science.gov (United States)

Zimmer, Robert J.; And Others

1996-01-01

A survey of 122 college teachers of marketing courses investigated the extent and methods of their inclusion of international marketing into the course curriculum. Findings suggest that, among those teaching international marketing, how they acquired their international knowledge had a significant effect on how they taught international marketing.…

International practice experiences in pharmacy education.

Science.gov (United States)

Cisneros, Robert M; Jawaid, Sarah Parnapy; Kendall, Debra A; McPherson, Charles E; Mu, Keli; Weston, Grady Scott; Roberts, Kenneth B

2013-11-12

To identify reasons for inclusion of international practice experiences in pharmacy curricula and to understand the related structure, benefits, and challenges related to the programs. A convenience sample of 20 colleges and schools of pharmacy in the United States with international pharmacy education programs was used. Telephone interviews were conducted by 2 study investigators. University values and strategic planning were among key driving forces in the development of programs. Global awareness and cultural competency requirements added impetus to program development. Participants' advice for creating an international practice experience program included an emphasis on the value of working with university health professions programs and established travel programs. Despite challenges, colleges and schools of pharmacy value the importance of international pharmacy education for pharmacy students as it increases global awareness of health needs and cultural competencies.

Implications of ICD-10 for Sarcopenia Clinical Practice and Clinical Trials: Report by the International Conference on Frailty and Sarcopenia Research Task Force.

Science.gov (United States)

Vellas, B; Fielding, R A; Bens, C; Bernabei, R; Cawthon, P M; Cederholm, T; Cruz-Jentoft, A J; Del Signore, S; Donahue, S; Morley, J; Pahor, M; Reginster, J-Y; Rodriguez Mañas, L; Rolland, Y; Roubenoff, R; Sinclair, A; Cesari, M

2018-01-01

Establishment of an ICD-10-CM code for sarcopenia in 2016 was an important step towards reaching international consensus on the need for a nosological framework of age-related skeletal muscle decline. The International Conference on Frailty and Sarcopenia Research Task Force met in April 2017 to discuss the meaning, significance, and barriers to the implementation of the new code as well as strategies to accelerate development of new therapies. Analyses by the Sarcopenia Definitions and Outcomes Consortium are underway to develop quantitative definitions of sarcopenia. A consensus conference is planned to evaluate this analysis. The Task Force also discussed lessons learned from sarcopenia trials that could be applied to future trials, as well as lessons from the osteoporosis field, a clinical condition with many constructs similar to sarcopenia and for which ad hoc treatments have been developed and approved by regulatory agencies.

Manipulating Light and Matter with Photonic Structures: Numerical Investigations on Photonic Crystals and Optical Forces

Science.gov (United States)

Zhang, Peng

The highly developed nano-fabrication techniques allow light to be modulated with photonic structures in a more intensive way. These photonic structures involve photonic crystals, metals supporting surface plasmon polaritons, metamaterials, etc. In this thesis work, three different ways for light manipulation are numerically investigated. First, the light propagation is modulated using a photonic crystal with Dirac cones. It is demonstrated that the zero-index behavior of this photonic crystal which happens for normal incident waves, is lost at oblique incidence. A new method combining complex-k band calculations and absorbing boundary conditions for Bloch modes is developed to analyze the Bloch mode interaction in details. Second, the mechanic states of graphene are modulated through the optical gradient force. This force is induced by the coupled surface plasmons on the double graphene sheets and is greatly enhanced in comparison to the regular waveguides. By applying different strengths of forces in accordance to the input power, the mechanic state transition is made possible, accompanied by an abrupt change in the transmission and reflection spectra. Third, the helicity/chirality of light is studied to modulate the lateral force on a small particle. A left-hand material slab which supports coherent TE ad TM plasmons simultaneously is introduced. By mixing the TE and TM surface plasmons with different relative phases, the lateral force on a chiral particle can be changed, which will be beneficial for chiral particle sorting.

Development of force adaptation during childhood.

Science.gov (United States)

Konczak, Jürgen; Jansen-Osmann, Petra; Kalveram, Karl-Theodor

2003-03-01

Humans learn to make reaching movements in novel dynamic environments by acquiring an internal motor model of their limb dynamics. Here, the authors investigated how 4- to 11-year-old children (N = 39) and adults (N = 7) adapted to changes in arm dynamics, and they examined whether those data support the view that the human brain acquires inverse dynamics models (IDM) during development. While external damping forces were applied, the children learned to perform goal-directed forearm flexion movements. After changes in damping, all children showed kinematic aftereffects indicative of a neural controller that still attempted to compensate the no longer existing damping force. With increasing age, the number of trials toward complete adaptation decreased. When damping was present, forearm paths were most perturbed and most variable in the youngest children but were improved in the older children. The findings indicate that the neural representations of limb dynamics are less precise in children and less stable in time than those of adults. Such controller instability might be a primary cause of the high kinematic variability observed in many motor tasks during childhood. Finally, the young children were not able to update those models at the same rate as the older children, who, in turn, adapted more slowly than adults. In conclusion, the ability to adapt to unknown forces is a developmental achievement. The present results are consistent with the view that the acquisition and modification of internal models of the limb dynamics form the basis of that adaptive process.

Force and Directional Force Modulation Effects on Accuracy and Variability in Low-Level Pinch Force Tracking.

Science.gov (United States)

Park, Sangsoo; Spirduso, Waneen; Eakin, Tim; Abraham, Lawrence

2018-01-01

The authors investigated how varying the required low-level forces and the direction of force change affect accuracy and variability of force production in a cyclic isometric pinch force tracking task. Eighteen healthy right-handed adult volunteers performed the tracking task over 3 different force ranges. Root mean square error and coefficient of variation were higher at lower force levels and during minimum reversals compared with maximum reversals. Overall, the thumb showed greater root mean square error and coefficient of variation scores than did the index finger during maximum reversals, but not during minimum reversals. The observed impaired performance during minimum reversals might originate from history-dependent mechanisms of force production and highly coupled 2-digit performance.

Analytical and numerical investigation of nonlinear internal gravity waves

Directory of Open Access Journals (Sweden)

S. P. Kshevetskii

2001-01-01

Full Text Available The propagation of long, weakly nonlinear internal waves in a stratified gas is studied. Hydrodynamic equations for an ideal fluid with the perfect gas law describe the atmospheric gas behaviour. If we neglect the term Ͽ dw/dt (product of the density and vertical acceleration, we come to a so-called quasistatic model, while we name the full hydro-dynamic model as a nonquasistatic one. Both quasistatic and nonquasistatic models are used for wave simulation and the models are compared among themselves. It is shown that a smooth classical solution of a nonlinear quasistatic problem does not exist for all t because a gradient catastrophe of non-linear internal waves occurs. To overcome this difficulty, we search for the solution of the quasistatic problem in terms of a generalised function theory as a limit of special regularised equations containing some additional dissipation term when the dissipation factor vanishes. It is shown that such solutions of the quasistatic problem qualitatively differ from solutions of a nonquasistatic nature. It is explained by the fact that in a nonquasistatic model the vertical acceleration term plays the role of a regularizator with respect to a quasistatic model, while the solution qualitatively depends on the regularizator used. The numerical models are compared with some analytical results. Within the framework of the analytical model, any internal wave is described as a system of wave modes; each wave mode interacts with others due to equation non-linearity. In the principal order of a perturbation theory, each wave mode is described by some equation of a KdV type. The analytical model reveals that, in a nonquasistatic model, an internal wave should disintegrate into solitons. The time of wave disintegration into solitons, the scales and amount of solitons generated are important characteristics of the non-linear process; they are found with the help of analytical and numerical investigations. Satisfactory

A report on older-age bipolar disorder from the International Society for Bipolar Disorders Task Force

Science.gov (United States)

Sajatovic, Martha; Strejilevich, Sergio A; Gildengers, Ariel G; Dols, Annemiek; Al Jurdi, Rayan K; Forester, Brent P; Kessing, Lars Vedel; Beyer, John; Manes, Facundo; Rej, Soham; Rosa, Adriane R; Schouws, Sigfried NTM; Tsai, Shang-Ying; Young, Robert C; Shulman, Kenneth I

2015-01-01

Objectives In the coming generation, older adults with bipolar disorder (BD) will increase in absolute numbers as well as proportion of the general population. This is the first report of the International Society for Bipolar Disorder (ISBD) Task Force on Older-Age Bipolar Disorder (OABD). Methods This task force report addresses the unique aspects of OABD including epidemiology and clinical features, neuropathology and biomarkers, physical health, cognition, and care approaches. Results The report describes an expert consensus summary on OABD that is intended to advance the care of patients, and shed light on issues of relevance to BD research across the lifespan. Although there is still a dearth of research and health efforts focused on older adults with BD, emerging data has brought some answers, innovative questions, and novel perspectives related to the notion of late onset, medical comorbidity, and the vexing issue of cognitive impairment and decline. Conclusions Improving our understanding of the biological, clinical, and social underpinnings relevant to OABD is an indispensable step in building a complete map of BD across the lifespan. PMID:26384588

Internally Displaced “Victims of Armed Conflict” in Colombia: The Trajectory and Trauma Signature of Forced Migration

Science.gov (United States)

Shultz, James M.; Garfin, Dana Rose; Espinel, Zelde; Araya, Ricardo; Oquendo, Maria A.; Wainberg, Milton L.; Chaskel, Roberto; Gaviria, Silvia L.; Ordóñez, Anna E.; Espinola, Maria; Wilson, Fiona E.; García, Natalia Muñoz; Ceballos, Ángela Milena Gómez; Garcia-Barcena, Yanira; Verdeli, Helen; Neria, Yuval

2016-01-01

While conflict-induced forced migration is a global phenomenon, the situation in Colombia, South America, is distinctive. Colombia has ranked either first or second in the number of internally displaced persons for 10 years, a consequence of decades of armed conflict compounded by high prevalence of drug trafficking. The displacement trajectory for displaced persons in Colombia proceeds through a sequence of stages: (1) pre-expulsion threats and vulnerability, (2) expulsion, (3) migration, (4) initial adaptation to relocation, (5) protracted resettlement (the end point for most forced migrants), and, rarely, (6) return to the community of origin. Trauma signature analysis, an evidence-based method that elucidates the physical and psychological consequences associated with exposures to harm and loss during disasters and complex emergencies, was used to identify the psychological risk factors and potentially traumatic events experienced by conflict-displaced persons in Colombia, stratified across the phases of displacement. Trauma and loss are experienced differentially throughout the pathway of displacement. PMID:25135775

Experimental investigations of heat transfer from an internally finned two phase closed thermosyphon

International Nuclear Information System (INIS)

Naresh, Y.; Balaji, C.

2017-01-01

Highlights: • Experimental investigations on an internally finned vertical thermosyphon. • Two fluids – water and acetone considered. • Optimum fill ratio determined to be 50%. • Addition of internal fins at the condenser leads to improved thermal performance. - Abstract: This paper reports the results of an experimental investigation of heat transfer from an internally finned thermosyphon charged with either water or acetone. Six constant area fins with a rectangular cross section are placed internally along the length at the condenser section. The ratio of initial liquid pool volume to the evaporator volume, known as the filling ratio in a thermosyphon system, has been varied in this study. Experiments are carried out for filling ratios of 20, 50, and 80% for two working fluids (i) water and (ii) acetone. Results show that a fill ratio of 50% gives better heat transfer performance. Providing internal fins at the condenser produces additional condensation which improves the thermal performance of the thermosyphon by 17% in terms of the temperature reduction at the source and sink and 35.48% in terms of reduction in thermal resistance at lower heat inputs. The thermosyphon is tested between power levels of 50 and 275 W.

Investigation of military training injuries in a special force corps in 2011

Directory of Open Access Journals (Sweden)

Gang ZHAO

2013-09-01

Full Text Available Objective　To investigate the incidence, related influencing factors and predilection sites of training injuries in a special force corps for providing a basis of effective prevention of the injuries. Methods　Four hundred and sixty-four officers and soldiers were randomly selected by lottery method from a special force corps in May 2011, and the training injuries as well as their related information was investigated by a questionnaire method. The medical records of the 464 subjects from May 2010 to May 2011 were reviewed. The collected data were statistically analyzed using SPSS 19.0 software. Results　Of the 464 subjects, 165(35.6% never experienced injuries, and 299(64.4% were injured due to training in the last one year. A total of 505 person-time injuries occurred in 464 subjects, and the incidence of injury was 109 per 100 person-year. The major risk factors for training injuries included above average age, fondness of multiple sports, greater labor force, or higher frequency of sport exercises before enlistment, poor sleep or diet caused by training burden, and higher SCL-90 somatization score. The major protective factors comprised of higher military rank, lower-intensity training, higher education level, higher labor frequency before enlistment, higher SCL-90 phobic anxiety score, higher SCL-90 depression score, SCL-90 spirit score, and higher satisfaction degree on training program. The major sites of training injuries were lower extremities and lower back (accounting for 73.0%. Most injuries occurred below the knee (accounting for 49.0%, including the foot (6.5%, ankle (13.6%, leg(7.3% and knee (21.6%, followed by the lower back (accounting for 20.7%. Conclusions　The risk factors of military training injuries involve various aspects, and continuous high intensive and highly difficult training items are the main reason of training injuries, and the lower extremities and lower back are the major locations. Psychological factors are

An investigation into electromagnetic force models: differences in global and local effects demonstrated by selected problems

Science.gov (United States)

Reich, Felix A.; Rickert, Wilhelm; Müller, Wolfgang H.

2018-03-01

This study investigates the implications of various electromagnetic force models in macroscopic situations. There is an ongoing academic discussion which model is "correct," i.e., generally applicable. Often, gedankenexperiments with light waves or photons are used in order to motivate certain models. In this work, three problems with bodies at the macroscopic scale are used for computing theoretical model-dependent predictions. Two aspects are considered, total forces between bodies and local deformations. By comparing with experimental data, insight is gained regarding the applicability of the models. First, the total force between two cylindrical magnets is computed. Then a spherical magnetostriction problem is considered to show different deformation predictions. As a third example focusing on local deformations, a droplet of silicone oil in castor oil is considered, placed in a homogeneous electric field. By using experimental data, some conclusions are drawn and further work is motivated.

Field Monitoring of Deformations and Internal Forces of Surrounding Rocks and Lining Structures in the Construction of the Gangkou Double-Arched Tunnel—A Case Study

Directory of Open Access Journals (Sweden)

Qixiang Yan

2017-02-01

Full Text Available Double-arched tunnel is a special and complex underground structure which needs to be monitored carefully during construction. Taking the Gangkou tunnel as the engineering background, this paper presents a case study of field monitoring of a representative double-arched tunnel. Typical cross sections were chosen in each class of surrounding rock masses in the tunnel area and different types of sensors were embedded in designed locations, and the deformations and forces of both surrounding rocks and lining structures were monitored systematically. The dynamic evolution as well as the spatial distribution characteristics of the monitoring data including the internal displacements of surrounding rocks and the contact pressures between surrounding rocks and primary linings, the axial forces in rock bolts and the internal forces in both steel arches and secondary linings were analyzed. The monitoring and analysis results show that the deformations and forces of both surrounding rocks and lining structures are directly related to the construction procedures, geological conditions and locations in the double-arched tunnel. According to the results, some reasonable suggestions were provided for the improvement of the tunnel construction. This study will provide useful reference and guidance for the design, construction and monitoring of similar engineering projects in future.

Investigating the binding behaviour of two avidin-based testosterone binders using molecular recognition force spectroscopy.

Science.gov (United States)

Rangl, Martina; Leitner, Michael; Riihimäki, Tiina; Lehtonen, Soili; Hytönen, Vesa P; Gruber, Hermann J; Kulomaa, Markku; Hinterdorfer, Peter; Ebner, Andreas

2014-02-01

Molecular recognition force spectroscopy, a biosensing atomic force microscopy technique allows to characterise the dissociation of ligand-receptor complexes at the molecular level. Here, we used molecular recognition force spectroscopy to study the binding capability of recently developed testosterone binders. The two avidin-based proteins called sbAvd-1 and sbAvd-2 are expected to bind both testosterone and biotin but differ in their binding behaviour towards these ligands. To explore the ligand binding and dissociation energy landscape of these proteins, we tethered biotin or testosterone to the atomic force microscopy probe while the testosterone-binding protein was immobilized on the surface. Repeated formation and rupture of the ligand-receptor complex at different pulling velocities allowed determination of the loading rate dependence of the complex-rupturing force. In this way, we obtained the molecular dissociation rate (k(off)) and energy landscape distances (x(β)) of the four possible complexes: sbAvd-1-biotin, sbAvd-1-testosterone, sbAvd-2-biotin and sbAvd-2-testosterone. It was found that the kinetic off-rates for both proteins and both ligands are similar. In contrast, the x(β) values, as well as the probability of complex formations, varied considerably. In addition, competitive binding experiments with biotin and testosterone in solution differ significantly for the two testosterone-binding proteins, implying a decreased cross-reactivity of sbAvd-2. Unravelling the binding behaviour of the investigated testosterone-binding proteins is expected to improve their usability for possible sensing applications. Copyright © 2014 John Wiley & Sons, Ltd.

An investigation of rugby scrimmaging posture and individual maximum pushing force.

Science.gov (United States)

Wu, Wen-Lan; Chang, Jyh-Jong; Wu, Jia-Hroung; Guo, Lan-Yuen

2007-02-01

Although rugby is a popular contact sport and the isokinetic muscle torque assessment has recently found widespread application in the field of sports medicine, little research has examined the factors associated with the performance of game-specific skills directly by using the isokinetic-type rugby scrimmaging machine. This study is designed to (a) measure and observe the differences in the maximum individual pushing forward force produced by scrimmaging in different body postures (3 body heights x 2 foot positions) with a self-developed rugby scrimmaging machine and (b) observe the variations in hip, knee, and ankle angles at different body postures and explore the relationship between these angle values and the individual maximum pushing force. Ten national rugby players were invited to participate in the examination. The experimental equipment included a self-developed rugby scrimmaging machine and a 3-dimensional motion analysis system. Our results showed that the foot positions (parallel and nonparallel foot positions) do not affect the maximum pushing force; however, the maximum pushing force was significantly lower in posture I (36% body height) than in posture II (38%) and posture III (40%). The maximum forward force in posture III (40% body height) was also slightly greater than for the scrum in posture II (38% body height). In addition, it was determined that hip, knee, and ankle angles under parallel feet positioning are factors that are closely negatively related in terms of affecting maximum pushing force in scrimmaging. In cross-feet postures, there was a positive correlation between individual forward force and hip angle of the rear leg. From our results, we can conclude that if the player stands in an appropriate starting position at the early stage of scrimmaging, it will benefit the forward force production.

Investigation of Tension Forces in A Stay Cable System of A Road Bridge Using Vibration Methods

Directory of Open Access Journals (Sweden)

Hawryszków Paweł

2015-01-01

Full Text Available In the article author presents method of investigation of tension forces in stay cable systems using dynamical methods. Research was carried out during stay cable system installation on WN-24 viaduct near Poznań, that is way it was possible to compare tension forces indicated directly by devices using for tensioning of cable-stayed bridges with results achieved indirectly by means of dynamical methods. Discussion of results was presented. Advantages of dynamical methods and possible fields of application was described. This method, which has been rarely used before, may occur interesting alternative in diagnostics of bridges in comparison to traditional methods.

A review of a method for dynamic load distribution, dynamic modeling, and explicit internal force control when two serial link manipulators mutually lift and transport a rigid body object

International Nuclear Information System (INIS)

Unseren, M.A.

1997-09-01

The report reviews a method for modeling and controlling two serial link manipulators which mutually lift and transport a rigid body object in a three dimensional workspace. A new vector variable is introduced which parameterizes the internal contact force controlled degrees of freedom. A technique for dynamically distributing the payload between the manipulators is suggested which yields a family of solutions for the contact forces and torques the manipulators impart to the object. A set of rigid body kinematic constraints which restricts the values of the joint velocities of both manipulators is derived. A rigid body dynamical model for the closed chain system is first developed in the joint space. The model is obtained by generalizing the previous methods for deriving the model. The joint velocity and acceleration variables in the model are expressed in terms of independent pseudovariables. The pseudospace model is transformed to obtain reduced order equations of motion and a separate set of equations governing the internal components of the contact forces and torques. A theoretic control architecture is suggested which explicitly decouples the two sets of equations comprising the model. The controller enables the designer to develop independent, non-interacting control laws for the position control and internal force control of the system

A review of a method for dynamic load distribution, dynamic modeling, and explicit internal force control when two serial link manipulators mutually lift and transport a rigid body object

Energy Technology Data Exchange (ETDEWEB)

Unseren, M.A.

1997-09-01

The report reviews a method for modeling and controlling two serial link manipulators which mutually lift and transport a rigid body object in a three dimensional workspace. A new vector variable is introduced which parameterizes the internal contact force controlled degrees of freedom. A technique for dynamically distributing the payload between the manipulators is suggested which yields a family of solutions for the contact forces and torques the manipulators impart to the object. A set of rigid body kinematic constraints which restricts the values of the joint velocities of both manipulators is derived. A rigid body dynamical model for the closed chain system is first developed in the joint space. The model is obtained by generalizing the previous methods for deriving the model. The joint velocity and acceleration variables in the model are expressed in terms of independent pseudovariables. The pseudospace model is transformed to obtain reduced order equations of motion and a separate set of equations governing the internal components of the contact forces and torques. A theoretic control architecture is suggested which explicitly decouples the two sets of equations comprising the model. The controller enables the designer to develop independent, non-interacting control laws for the position control and internal force control of the system.

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

Science.gov (United States)

Neuman, Keir C.; Nagy, Attila

2012-01-01

Single-molecule force spectroscopy has emerged as a powerful tool to investigate the forces and motions associated with biological molecules and enzymatic activity. The most common force spectroscopy techniques are optical tweezers, magnetic tweezers and atomic force microscopy. These techniques are described and illustrated with examples highlighting current capabilities and limitations. PMID:18511917

(Environmental investigation of ground water contamination at Wright-Patterson Air Force Base, Ohio)

Energy Technology Data Exchange (ETDEWEB)

1992-03-01

An environmental investigation of ground water conditions has been undertaken at Wright-Patterson Air Force Base (WPAFB), Ohio to obtain data to assist in the evaluation of a potential removal action to prevent, to the extent practicable, migration of the contaminated ground water across Base boundaries. Field investigations were limited to the central section of the southwestern boundary of Area C and the Springfield Pike boundary of Area B. Further, the study was limited to a maximum depth of 150 feet below grade. Three primary activities of the field investigation were: (1) installation of 22 monitoring wells, (2) collection and analysis of ground water from 71 locations, (3) measurement of ground water elevations at 69 locations. Volatile organic compounds including trichloroethylene, perchloroethylene, and/or vinyl chloride were detected in concentrations exceeding Maximum Contaminant Levels (MCL) at three locations within the Area C investigation area. Ground water at the Springfield Pike boundary of Area B occurs in two primary units, separated by a thicker-than-expected clay layers. One well within Area B was determined to exceed the MCL for trichloroethylene.

Task Force report

International Nuclear Information System (INIS)

Anon.

1987-01-01

The International Task Force on Prevention of Nuclear Terrorism was formed in 1985 under the auspices of the Nuclear Control Institute. This report is a consensus report of the 26 task force members - all members not necessarily agreeing on every point and all wordings, but in each case a substantial majority did agree. First, the report defines the threat, then establishes the priorities. Short-term recommendations are presented on: (1) protecting nuclear weapons; (2) protecting nuclear materials; (3) protecting nuclear facilities; (4) intelligence programs; (5) civil liberties concerns; (6) controlling nuclear transfers; (7) US - Soviet cooperation; (8) arms control initiatives; (9) convention of physical protection of nuclear material; (10) role of emergency management programs; and (11) role of the media. Brief long-term recommendations are included on (1) international measures, and (2) emerging nuclear technologies. An Appendix, Production of Nuclear Materials Usable in Weapons is presented for further consideration (without recommendations)

Substrate binding to SGLT1 investigated by single molecule force spectroscopy

International Nuclear Information System (INIS)

Neundlinger, I. J.

2010-01-01

D-glucose serves as one of the most important fuels in various organism due to its fundamental role in ATP-, protein and lipid synthesis. Thus, sustaining glucose homeostasis is a crucial issue of life as disorders can cause severe malfunctions such as glucose-galactose-malabsorbtion (GGM). Sodium-glucose co-transporter, SGLTs, especially the high affinity transporter SGLT1, play a crucial role in accumulation of glucose in the cell as they facilitate transport of the sugar into the cytoplasma across the cell membrane by a Na+-electrochemical potential. Even recently, members of the SGLT transporter family have become a therapeutic target for the treatment of hyperglycemia in type 2 diabetes. Hence, it is of particular importance to gain insights on the dynamic behavior of SGLTs during substrate binding and transport across the cell membrane on the single molecular level. In the present study, the Atomic Force Microscope (AFM) was employed to investigate the dynamic properties of the sodium-glucose co-transporter SGLT1 upon substrate binding under nearly physiological conditions. Hereto, new glucose derivatives were synthesized in order to probe the recognition efficiency of these molecules to SGLT1 embedded in the plasma membrane of living cells. A well established coupling protocol was used to covalently link (i) amino-modified D-glucose owning a conserved pyranose ring, (ii) 1-thio-β-D-glucose having a sulphur atom at C1 of the pyranose ring and (iii) the competitive inhibitor phlorizin to the AFM tip via poly(ethylene)glycol (PEG)-tether using different functional end groups and varying lengths. Binding characteristics, e.g. binding probability, interaction forces, influence of substances (glucose, phlorizin, sodium) and of molecule-linker compounds were obtained by performing single molecular recognition force spectroscopy (SMRFS) measurements. Moreover, temperature controlled radioactive binding/transport assays and SMRFS experiments yielded insights into

Investigation of adhesion and mechanical properties of human glioma cells by single cell force spectroscopy and atomic force microscopy.

Science.gov (United States)

Andolfi, Laura; Bourkoula, Eugenia; Migliorini, Elisa; Palma, Anita; Pucer, Anja; Skrap, Miran; Scoles, Giacinto; Beltrami, Antonio Paolo; Cesselli, Daniela; Lazzarino, Marco

2014-01-01

Active cell migration and invasion is a peculiar feature of glioma that makes this tumor able to rapidly infiltrate into the surrounding brain tissue. In our recent work, we identified a novel class of glioma-associated-stem cells (defined as GASC for high-grade glioma--HG--and Gasc for low-grade glioma--LG) that, although not tumorigenic, act supporting the biological aggressiveness of glioma-initiating stem cells (defined as GSC for HG and Gsc for LG) favoring also their motility. Migrating cancer cells undergo considerable molecular and cellular changes by remodeling their cytoskeleton and cell interactions with surrounding environment. To get a better understanding about the role of the glioma-associated-stem cells in tumor progression, cell deformability and interactions between glioma-initiating stem cells and glioma-associated-stem cells were investigated. Adhesion of HG/LG-cancer cells on HG/LG-glioma-associated stem cells was studied by time-lapse microscopy, while cell deformability and cell-cell adhesion strengths were quantified by indentation measurements by atomic force microscopy and single cell force spectroscopy. Our results demonstrate that for both HG and LG glioma, cancer-initiating-stem cells are softer than glioma-associated-stem cells, in agreement with their neoplastic features. The adhesion strength of GSC on GASC appears to be significantly lower than that observed for Gsc on Gasc. Whereas, GSC spread and firmly adhere on Gasc with an adhesion strength increased as compared to that obtained on GASC. These findings highlight that the grade of glioma-associated-stem cells plays an important role in modulating cancer cell adhesion, which could affect glioma cell migration, invasion and thus cancer aggressiveness. Moreover this work provides evidence about the importance of investigating cell adhesion and elasticity for new developments in disease diagnostics and therapeutics.

Investigating the effect of clamping force on the fatigue life of bolted plates using volumetric approach

International Nuclear Information System (INIS)

Esmaeili, F.; Chakherlou, T. N.; Zehsaz, M.; Hasanifard, S.

2013-01-01

In this paper, the effects of bolt clamping force on the fatigue life for bolted plates made from Al7075-T6 have been studied on the values of notch strength reduction factor obtained by volumetric approach. To attain stress distribution around the notch (hole) which is required for volumetric approach, nonlinear finite element simulations were carried out. To estimate the fatigue life, the available smooth S-N curve of Al7075-T6 and the notch strength reduction factor obtained from volumetric method were used. The estimated fatigue life was compared with the available experimental test results. The investigation shows that there is a good agreement between the life predicted by the volumetric approach and the experimental results for various specimens with different amount of clamping forces. Volumetric approach and experimental results showed that the fatigue life of bolted plates improves because of the compressive stresses created around the plate hole due to clamping force.

An investigation of transition boiling mechanisms of subcooled water under forced convective conditions

Energy Technology Data Exchange (ETDEWEB)

Kwang-Won, Lee; Sang-Yong, Lee

1995-09-01

A mechanistic model for forced convective transition boiling has been developed to investigate transition boiling mechanisms and to predict transition boiling heat flux realistically. This model is based on a postulated multi-stage boiling process occurring during the passage time of the elongated vapor blanket specified at a critical heat flux (CHF) condition. Between the departure from nucleate boiling (DNB) and the departure from film boiling (DFB) points, the boiling heat transfer is established through three boiling stages, namely, the macrolayer evaporation and dryout governed by nucleate boiling in a thin liquid film and the unstable film boiling characterized by the frequent touches of the interface and the heated wall. The total heat transfer rates after the DNB is weighted by the time fractions of each stage, which are defined as the ratio of each stage duration to the vapor blanket passage time. The model predictions are compared with some available experimental transition boiling data. The parametric effects of pressure, mass flux, inlet subcooling on the transition boiling heat transfer are also investigated. From these comparisons, it can be seen that this model can identify the crucial mechanisms of forced convective transition boiling, and that the transition boiling heat fluxes including the maximum heat flux and the minimum film boiling heat flux are well predicted at low qualities/high pressures near 10 bar. In future, this model will be improved in the unstable film boiling stage and generalized for high quality and low pressure situations.

The formulation of a peer evaluation measure for special forces: operational forces operator traits and attitude questionnaire (SFO-TAQ)

CSIR Research Space (South Africa)

Van Heerden, A

2016-11-01

Full Text Available International Military Testing Association (IMTA) Conference, New Delhi, India, 7-11 November 2016 The formulation of a peer evaluation measure for special forces: operational forces operator traits and attitude questionnaire (SFO-TAQ) Van Heerden A...

Nonlinear Forced Vibration of a Viscoelastic Buckled Beam with 2 : 1 Internal Resonance

Directory of Open Access Journals (Sweden)

Liu-Yang Xiong

2014-01-01

Full Text Available Nonlinear dynamics of a viscoelastic buckled beam subjected to primary resonance in the presence of internal resonance is investigated for the first time. For appropriate choice of system parameters, the natural frequency of the second mode is approximately twice that of the first providing the condition for 2 : 1 internal resonance. The ordinary differential equations of the two mode shapes are established using the Galerkin method. The problem is replaced by two coupled second-order differential equations with quadratic and cubic nonlinearities. The multiple scales method is applied to derive the modulation-phase equations. Steady-state solutions of the system as well as their stability are examined. The frequency-amplitude curves exhibit the steady-state response in the directly excited and indirectly excited modes due to modal interaction. The double-jump, the saturation phenomenon, and the nonperiodic region phenomena are observed illustrating the influence of internal resonance. The validity range of the analytical approximations is assessed by comparing the analytical approximate results with a numerical solution by the Runge-Kutta method. The unstable regions in the internal resonance are explored via numerical simulations.

The vibrational source strength descriptor using power input from equivalent forces: a simulation study

DEFF Research Database (Denmark)

Laugesen, Søren; Ohlrich, Mogens

1994-01-01

Simple, yet reliable methods for the approximate determination of the vibratory power supplied by the internal excitation forces of a given vibrational source are of great interest. One such method that relies on the application of a number of “equivalent forces” and measurements of the mean...... squared velocity on either the source or the receiving structure is studied in this paper by means of computer simulations. The study considers a simple system of two flexural beams coupled via a pair of springs. The investigation shows that a relatively small number of equivalent forces suffice...

Investigation into local cell mechanics by atomic force microscopy mapping and optical tweezer vertical indentation.

Science.gov (United States)

Coceano, G; Yousafzai, M S; Ma, W; Ndoye, F; Venturelli, L; Hussain, I; Bonin, S; Niemela, J; Scoles, G; Cojoc, D; Ferrari, E

2016-02-12

Investigating the mechanical properties of cells could reveal a potential source of label-free markers of cancer progression, based on measurable viscoelastic parameters. The Young's modulus has proved to be the most thoroughly studied so far, however, even for the same cell type, the elastic modulus reported in different studies spans a wide range of values, mainly due to the application of different experimental conditions. This complicates the reliable use of elasticity for the mechanical phenotyping of cells. Here we combine two complementary techniques, atomic force microscopy (AFM) and optical tweezer microscopy (OTM), providing a comprehensive mechanical comparison of three human breast cell lines: normal myoepithelial (HBL-100), luminal breast cancer (MCF-7) and basal breast cancer (MDA-MB-231) cells. The elastic modulus was measured locally by AFM and OTM on single cells, using similar indentation approaches but different measurement parameters. Peak force tapping AFM was employed at nanonewton forces and high loading rates to draw a viscoelastic map of each cell and the results indicated that the region on top of the nucleus provided the most meaningful results. OTM was employed at those locations at piconewton forces and low loading rates, to measure the elastic modulus in a real elastic regime and rule out the contribution of viscous forces typical of AFM. When measured by either AFM or OTM, the cell lines' elasticity trend was similar for the aggressive MDA-MB-231 cells, which were found to be significantly softer than the other two cell types in both measurements. However, when comparing HBL-100 and MCF-7 cells, we found significant differences only when using OTM.

A report on older-age bipolar disorder from the International Society for Bipolar Disorders Task Force.

Science.gov (United States)

Sajatovic, Martha; Strejilevich, Sergio A; Gildengers, Ariel G; Dols, Annemiek; Al Jurdi, Rayan K; Forester, Brent P; Kessing, Lars Vedel; Beyer, John; Manes, Facundo; Rej, Soham; Rosa, Adriane R; Schouws, Sigfried Ntm; Tsai, Shang-Ying; Young, Robert C; Shulman, Kenneth I

2015-11-01

In the coming generation, older adults with bipolar disorder (BD) will increase in absolute numbers as well as proportion of the general population. This is the first report of the International Society for Bipolar Disorder (ISBD) Task Force on Older-Age Bipolar Disorder (OABD). This task force report addresses the unique aspects of OABD including epidemiology and clinical features, neuropathology and biomarkers, physical health, cognition, and care approaches. The report describes an expert consensus summary on OABD that is intended to advance the care of patients, and shed light on issues of relevance to BD research across the lifespan. Although there is still a dearth of research and health efforts focused on older adults with BD, emerging data have brought some answers, innovative questions, and novel perspectives related to the notion of late onset, medical comorbidity, and the vexing issue of cognitive impairment and decline. Improving our understanding of the biological, clinical, and social underpinnings relevant to OABD is an indispensable step in building a complete map of BD across the lifespan. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Consistent force fields for saccharides

DEFF Research Database (Denmark)

Rasmussen, Kjeld

1999-01-01

Consistent force fields for carbohydrates were hitherto developed by extensive optimization ofpotential energy function parameters on experimental data and on ab initio results. A wide range of experimental data is used: internal structures obtained from gas phase electron diffraction and from x......-anomeric effects are accounted for without addition of specific terms. The work is done in the framework of the Consistent Force Field which originatedin Israel and was further developed in Denmark. The actual methods and strategies employed havebeen described previously. Extensive testing of the force field...

Antiphospholipid Syndrome Clinical Research Task Force Report

NARCIS (Netherlands)

Erkan, D.; Derksen, R.; Levy, R.; Machin, S.; Ortel, T.; Pierangeli, S.; Roubey, R.; Lockshin, M.

The Antiphospholipid Syndrome (APS) Clinical Research Task Force (CRTF) was one of six Task Forces developed by the 13(th) International Congress on Antiphospholipid Antibodies (aPL) organization committee with the purpose of: a) evaluating the limitations of APS clinical research and developing

Computational model to investigate the relative contributions of different neuromuscular properties of tibialis anterior on force generated during ankle dorsiflexion.

Science.gov (United States)

Siddiqi, Ariba; Poosapadi Arjunan, Sridhar; Kumar, Dinesh Kant

2018-01-16

This study describes a new model of the force generated by tibialis anterior muscle with three new features: single-fiber action potential, twitch force, and pennation angle. This model was used to investigate the relative effects and interaction of ten age-associated neuromuscular parameters. Regression analysis (significance level of 0.05) between the neuromuscular properties and corresponding simulated force produced at the footplate was performed. Standardized slope coefficients were computed to rank the effect of the parameters. The results show that reduction in the average firing rate is the reason for the sharp decline in the force and other factors, such as number of muscle fibers, specific force, pennation angle, and innervation ratio. The fast fiber ratio affects the simulated force through two significant interactions. This study has ranked the individual contributions of the neuromuscular factors to muscle strength decline of the TA and identified firing rate decline as the biggest cause followed by decrease in muscle fiber number and specific force. The strategy for strength preservation for the elderly should focus on improving firing rate. Graphical abstract Neuromuscular properties of Tibialis Anterior on force generated during ankle dorsiflexion.

International outbreak investigation of Salmonella Heidelberg associated with in-flight catering.

Science.gov (United States)

Rebolledo, J; Garvey, P; Ryan, A; O'Donnell, J; Cormican, M; Jackson, S; Cloak, F; Cullen, L; Swaan, C M; Schimmer, B; Appels, R W; Nygard, K; Finley, R; Sreenivasan, N; Lenglet, A; Gossner, C; McKeown, P

2014-04-01

Rapid and wide dispersal of passengers after flights makes investigation of flight-related outbreaks challenging. An outbreak of Salmonella Heidelberg was identified in a group of Irish travellers returning from Tanzania. Additional international cases sharing the same flight were identified. Our aim was to determine the source and potential vehicles of infection. Case-finding utilized information exchange using experts' communication networks and national surveillance systems. Demographic, clinical and food history information was collected. Twenty-five additional cases were identified from Ireland, The Netherlands, Norway, USA and Canada. We conducted a case-control study which indicated a significant association between illness and consumption of milk tart (OR 10.2) and an egg dish (OR 6) served on-board the flight. No food consumed before the flight was associated with illness. Cases from countries other than Ireland provided supplementary information that facilitated the identification of likely vehicles of infection. Timely, committed international collaboration is vital in such investigations.

International outbreak investigation of Salmonella Heidelberg associated with in-flight catering.

LENUS (Irish Health Repository)

Rebolledo, J

2013-07-26

SUMMARY Rapid and wide dispersal of passengers after flights makes investigation of flight-related outbreaks challenging. An outbreak of Salmonella Heidelberg was identified in a group of Irish travellers returning from Tanzania. Additional international cases sharing the same flight were identified. Our aim was to determine the source and potential vehicles of infection. Case-finding utilized information exchange using experts\\' communication networks and national surveillance systems. Demographic, clinical and food history information was collected. Twenty-five additional cases were identified from Ireland, The Netherlands, Norway, USA and Canada. We conducted a case-control study which indicated a significant association between illness and consumption of milk tart (OR 10·2) and an egg dish (OR 6) served on-board the flight. No food consumed before the flight was associated with illness. Cases from countries other than Ireland provided supplementary information that facilitated the identification of likely vehicles of infection. Timely, committed international collaboration is vital in such investigations.

Chromosome structure investigated with the atomic force microscope

NARCIS (Netherlands)

de Grooth, B.G.; Putman, C.A.J.; Putman, Constant A.; van der Werf, Kees; van Hulst, N.F.; van Oort, G.; van Oort, Geeske; Greve, Jan; Manne, Srinivas

1992-01-01

We have developed an atomic force microscope (AFM) with an integrated optical microscope. The optical microscope consists of an inverted epi-illumination system that yields images in reflection or fluorescence of the sample. With this system it is possible to quickly locate an object of interest. A

Investigating the dependence of SCM simulated precipitation and clouds on the spatial scale of large-scale forcing at SGP

Science.gov (United States)

Tang, Shuaiqi; Zhang, Minghua; Xie, Shaocheng

2017-08-01

Large-scale forcing data, such as vertical velocity and advective tendencies, are required to drive single-column models (SCMs), cloud-resolving models, and large-eddy simulations. Previous studies suggest that some errors of these model simulations could be attributed to the lack of spatial variability in the specified domain-mean large-scale forcing. This study investigates the spatial variability of the forcing and explores its impact on SCM simulated precipitation and clouds. A gridded large-scale forcing data during the March 2000 Cloud Intensive Operational Period at the Atmospheric Radiation Measurement program's Southern Great Plains site is used for analysis and to drive the single-column version of the Community Atmospheric Model Version 5 (SCAM5). When the gridded forcing data show large spatial variability, such as during a frontal passage, SCAM5 with the domain-mean forcing is not able to capture the convective systems that are partly located in the domain or that only occupy part of the domain. This problem has been largely reduced by using the gridded forcing data, which allows running SCAM5 in each subcolumn and then averaging the results within the domain. This is because the subcolumns have a better chance to capture the timing of the frontal propagation and the small-scale systems. Other potential uses of the gridded forcing data, such as understanding and testing scale-aware parameterizations, are also discussed.

Investigation of the Effect of Neck Muscle Active Force on Whiplash Injury of the Cervical Spine

Directory of Open Access Journals (Sweden)

Yu Yan

2018-01-01

Full Text Available The objective of the present study is to investigate the influence of neck muscle activation on whiplash neck injury of the occupants of a passenger vehicle under different severities of frontal and rear-end impact collisions. The finite element (FE model has been used as a versatile tool to simulate and understand the whiplash injury mechanism for occupant injury prevention. However, whiplash injuries and injury mechanisms have rarely been investigated in connection with neck active muscle forces, which restricts the complete reappearance and understanding of the injury mechanism. In this manuscript, a mixed FE human model in a sitting posture with an active head-neck was developed. The response of the cervical spine under frontal and rear-end collision conditions was then studied using the FE model with and without neck muscle activation. The effect of the neck muscle activation on the whiplash injury was studied based on the results of the FE simulations. The results indicated that the neck active force influenced the head-neck dynamic response and whiplash injury during a collision, especially in a low-speed collision.

One-to-One and Three-to-One Internal Resonances in MEMS Shallow Arches

KAUST Repository

Ouakad, Hassen M.; Sedighi, Hamid M.; Younis, Mohammad I.

2017-01-01

an investigation into the potential nonlinear internal resonances of a Micro electro mechanical systems MEMS arch when excited by static (DC) and dynamic (AC) electric forces. The influences of initial rise and mid-plane stretching are considered in the governing

The ICC, International Criminal Justice and International Politics ...

African Journals Online (AJOL)

The International Criminal Court (ICC) came into being as a result of a desire by the international community to establish a permanent body to deliver criminal justice instead of the formula of ad hoc tribunals that had become the norm. The coming into force of the Rome Statute in 2002 was greeted with euphoria as it ...

Psychological treatments for adults and children with epilepsy: Evidence-based recommendations by the International League Against Epilepsy Psychology Task Force.

Science.gov (United States)

Michaelis, Rosa; Tang, Venus; Goldstein, Laura H; Reuber, Markus; LaFrance, William Curt; Lundgren, Tobias; Modi, Avani C; Wagner, Janelle L

2018-06-19

Given the significant impact that psychosocial factors and epilepsy treatments can have on the health-related quality of life (HRQOL) of individuals with epilepsy and their families, there is great clinical interest in the role of psychological evaluation and treatments to improve HRQOL and comorbidities. Therefore, the International League Against Epilepsy (ILAE) charged the Psychology Task Force with the development of recommendations for clinical care based on evaluation of the evidence from their recent Cochrane review of psychological treatments in individuals with epilepsy. The literature search for a recent Cochrane review of randomized controlled trials investigating psychological treatments for individuals with epilepsy constitutes the key source of evidence for this article. To provide practical guidance to service providers, we provide ratings on study research designs based on (1) the American Academy of Neurology's Level of Evidence system and (2) the Grading of Recommendations, Assessment, Development, and Evaluation system. This paper is the culmination of an international collaboration process involving pediatric and adult psychologists, neurologists, psychiatrists, and neuropsychiatrists. The process and conclusions were reviewed and approved by the ILAE Executive Committee. The strongest evidence for psychological interventions was identified for the most common mental health problems, including depression, neurocognitive disturbances, and medication adherence. Psychological interventions targeting the enhancement of HRQOL and adherence and a decrease in comorbidity symptoms (anxiety, depression) should be incorporated into comprehensive epilepsy care. There is a range of psychological strategies (ie, cognitive behavioral therapy and mindfulness-based therapies) that show promise for improving the lives of persons with epilepsy, and clinical recommendations are provided to assist epilepsy health care providers in treating the comorbidities and

Analytical model of cracking due to rebar corrosion expansion in concrete considering the structure internal force

Science.gov (United States)

Lin, Xiangyue; Peng, Minli; Lei, Fengming; Tan, Jiangxian; Shi, Huacheng

2017-12-01

Based on the assumptions of uniform corrosion and linear elastic expansion, an analytical model of cracking due to rebar corrosion expansion in concrete was established, which is able to consider the structure internal force. And then, by means of the complex variable function theory and series expansion technology established by Muskhelishvili, the corresponding stress component functions of concrete around the reinforcement were obtained. Also, a comparative analysis was conducted between the numerical simulation model and present model in this paper. The results show that the calculation results of both methods were consistent with each other, and the numerical deviation was less than 10%, proving that the analytical model established in this paper is reliable.

Investigation of flow mechanism of a robotic fish swimming by using flow visualization synchronized with hydrodynamic force measurement

Science.gov (United States)

Tan, Guang-Kun; Shen, Gong-Xin; Huang, Shuo-Qiao; Su, Wen-Han; Ke, Yu

When swimming in water by flapping its tail, a fish can overcome the drag from uniform flow and propel its body. The involved flow mechanism concerns 3-D and unsteady effects. This paper presents the investigation of the flow mechanism on the basis of a 3-D robotic fish model which has the typical geometry of body and tail with periodic flapping 2-freedom kinematical motion testing in the case of St = 0.78, Re = 6,600 and phase delay mode (φ = - 75°), in which may have a greater or maximum propulsion (without consideration of the optimal efficiency). Using a special technique of dye visualization which can clearly show vortex sheet and vortices in detail and using the inner 3-component force balance and cable supporting system with the phase-lock technique, the 3-D flow structure visualized in the wake of fish and the hydrodynamic force measurement were synchronized and obtained. Under the mentioned flapping parameters, we found the key flow structure and its evolution, a pair of complex 3-D chain-shape vortex (S-H vortex-rings, S1 - H1 and S2 - H2, and their legs L1 and L2) flow structures, which attach the leading edge and the trailing edge, then shed, move downstream and outwards and distribute two antisymmetric staggering arrays along with the wake of the fish model in different phase stages during the flapping period. It is different with in the case of St = 0.25-0.35. Its typical flow structure and evolution are described and the results prove that they are different from the viewpoints based on the investigation of 2-D cases. For precision of the dynamic force measurement, in this paper it was provided with the method and techniques by subtracting the inertial forces and the forces induced by buoyancy and gravity effect in water, etc. from original data measured. The evolution of the synchronized measuring forces directly matching with the flow structure was also described in this paper.

International Business Cycle

Directory of Open Access Journals (Sweden)

Marek Lubiński

2007-04-01

Full Text Available Prime stylized facts of international business cycle theory refer to positive correlation in the cyclical components of important macroeconomic variables across countries. However a number of indicators of business cycle synchronization do not point to clear trends. It can be ascribed to the fact that different forces influence level of business cycle correlation. When investigating into the forces behind the commonness in aggregate fluctuations economic research seems to have pointed in two directions. One strand of the literature examines the idea of common exogenous shocks that affect economies simultaneously. In addition to that economic interdependencies such as trade in goods and services or capital account transactions may serve as the channels through which disturbances spill over across countries.The observed degree of output co movement reflects both the nature of the shocks that have occurred and the degree of economic interdependence. In the periods when common shocks prevail level of synchronization is usually higher than in times of transmission dominance.

Three-nucleon forces

International Nuclear Information System (INIS)

Sauer, P.U.

2014-01-01

In this paper, the role of three-nucleon forces in ab initio calculations of nuclear systems is investigated. The difference between genuine and induced many-nucleon forces is emphasized. Induced forces arise in the process of solving the nuclear many-body problem as technical intermediaries toward calculationally converged results. Genuine forces make up the Hamiltonian. They represent the chosen underlying dynamics. The hierarchy of contributions arising from genuine two-, three- and many-nucleon forces is discussed. Signals for the need of the inclusion of genuine three-nucleon forces are studied in nuclear systems, technically best under control, especially in three-nucleon and four-nucleon systems. Genuine three-nucleon forces are important for details in the description of some observables. Their contributions to observables are small on the scale set by two-nucleon forces. (author)

High-resolution noncontact AFM and Kelvin probe force microscopy investigations of self-assembled photovoltaic donor–acceptor dyads

Directory of Open Access Journals (Sweden)

Benjamin Grévin

2016-06-01

Full Text Available Self-assembled donor–acceptor dyads are used as model nanostructured heterojunctions for local investigations by noncontact atomic force microscopy (nc-AFM and Kelvin probe force microscopy (KPFM. With the aim to probe the photo-induced charge carrier generation, thin films deposited on transparent indium tin oxide substrates are investigated in dark conditions and upon illumination. The topographic and contact potential difference (CPD images taken under dark conditions are analysed in view of the results of complementary transmission electron microscopy (TEM experiments. After in situ annealing, it is shown that the dyads with longer donor blocks essentially lead to standing acceptor–donor lamellae, where the acceptor and donor groups are π-stacked in an edge-on configuration. The existence of strong CPD and surface photo-voltage (SPV contrasts shows that structural variations occur within the bulk of the edge-on stacks. SPV images with a very high lateral resolution are achieved, which allows for the resolution of local photo-charging contrasts at the scale of single edge-on lamella. This work paves the way for local investigations of the optoelectronic properties of donor–acceptor supramolecular architectures down to the elementary building block level.

The Evolution of the International Business Field

DEFF Research Database (Denmark)

Liesch, Peter W.; Håkanson, Lars; McGaughey, Sara L.

2011-01-01

Macro-environmental trends such as technological changes, declining trade and investment barriers, and globalizing forces impacting both markets and production worldwide point to the heightened importance of international business (IB) and the relevance of IB research today. Despite this, a leading...... scholar has expressed concerns that the IB research agenda could be ‘running out of steam’ (Buckley, Journal of International Business Studies 33(2):365–373, 2002), prompting on-going introspection within the IB field. We contribute to this debate by investigating the evolution of the IB field through...... a scientometric examination of articles published in its premier journal, the Journal of International Business Studies (JIBS) from 1970 until 2008. We introduce a new analytical tool, Leximancer, to the fields of international business and scientometry. We show an evolution from an initial and extended emphasis...

An Evolution in Research Practice for Investigating International Business Relationships

Directory of Open Access Journals (Sweden)

Anne HAMPTON

2013-09-01

Full Text Available The purpose of this paper is to discuss the development and rationale of research methodology for a specific topic of research. The topic in question is an investigation into international business relationships, a complex subject and one that is very topical in the growing world of international business. It is intended to examine the logical development of research practice in our study and to show the changing thought processes and justifications we have made over a period of time. It is hoped that this discussion paper will be helpful to academics and students alike, as so often research methodology is only discussed in terms of the final method/techniques chosen with an emphasis on the technical aspects of the methods rather than relating them to the subject to be researched.

Representing delayed force feedback as a combination of current and delayed states.

Science.gov (United States)

Avraham, Guy; Mawase, Firas; Karniel, Amir; Shmuelof, Lior; Donchin, Opher; Mussa-Ivaldi, Ferdinando A; Nisky, Ilana

2017-10-01

To adapt to deterministic force perturbations that depend on the current state of the hand, internal representations are formed to capture the relationships between forces experienced and motion. However, information from multiple modalities travels at different rates, resulting in intermodal delays that require compensation for these internal representations to develop. To understand how these delays are represented by the brain, we presented participants with delayed velocity-dependent force fields, i.e., forces that depend on hand velocity either 70 or 100 ms beforehand. We probed the internal representation of these delayed forces by examining the forces the participants applied to cope with the perturbations. The findings showed that for both delayed forces, the best model of internal representation consisted of a delayed velocity and current position and velocity. We show that participants relied initially on the current state, but with adaptation, the contribution of the delayed representation to adaptation increased. After adaptation, when the participants were asked to make movements with a higher velocity for which they had not previously experienced with the delayed force field, they applied forces that were consistent with current position and velocity as well as delayed velocity representations. This suggests that the sensorimotor system represents delayed force feedback using current and delayed state information and that it uses this representation when generalizing to faster movements. NEW & NOTEWORTHY The brain compensates for forces in the body and the environment to control movements, but it is unclear how it does so given the inherent delays in information transmission and processing. We examined how participants cope with delayed forces that depend on their arm velocity 70 or 100 ms beforehand. After adaptation, participants applied opposing forces that revealed a partially correct representation of the perturbation using the current and the

Joining forces with donor partners | IDRC - International ...

International Development Research Centre (IDRC) Digital Library (Canada)

Equally important, they increase the resources available to research for development. ... (CIDA), for the Canadian International Food Security Research Fund (CIFSRF). ... New animal vaccines could keep more African farmers in business.

Investigation of graphite composite anodes surfaces by atomic force microscopy and related techniques

Energy Technology Data Exchange (ETDEWEB)

Hirasawa, Karen Akemi; Nishioka, Keiko; Sato, Tomohiro; Yamaguchi, Shoji; Mori, Shoichiro [Mitsubishi Chemical Corp., Tsukuba Research Center, Ibaraki (Japan)

1997-11-01

The surface of a synthetic graphite (KS-44) and polyvinylidene difluoride binder (PVDF) anode for lithium-ion secondary batteries is imaged using atomic force microscopy (AFM) and several related scanning probe microscope (SPM) instruments including: dynamic force microscopy (DFM), friction force microscopy (FFM), laterally-modulated friction force microscopy (LM-FFM), visco-elasticity atomic force microscopy (VE-AFM), and AFM/simultaneous current measurement mode (SCM). DFM is found to be an exceptional mode for topographic imaging while FFM results in the clearest contrast distinction between PVDF binder and KS-44 graphite regions. (orig.)

Cogging force investigation of a free piston permanent magnet linear generator

Science.gov (United States)

Abdalla, I. I.; Zainal, A. E. Z.; Ramlan, N. A.; Firmansyah; Aziz, A. R. A.; Heikal, M. R.

2017-10-01

Better performance and higher efficiency of the vehicles can be achieved by using free piston engine, in which the piston is connected directly to the linear generator and waiving of any mechanical means. The free piston engine has the ability to overcome or reduce many of the challenges, such as the carbon dioxide (CO2) emission and fossil fuel consumption. The cogging force produces undesired vibration and acoustic noise in the generator. However, the cogging force must be minimized as much as possible, in order to have a high performance. This paper studies the effects of ferromagnetic materials on the cogging force of the permanent magnet linear generator (PMLG) to be used in a free piston engine using nonlinear finite-element analysis (FEA) under ANSYS Maxwell. The comparisons have been established for the cogging force of the PMLG under various translator velocities and three different ferromagnetic materials for the stator core, namely, Silicon Steel laminations, Mild Steel and Somaloy. It has been shown that the PMLG with a stator core made of Somaloy has a lower cogging force among them. Furthermore, the induced voltage of the PMLG at different accelerations has been studied. It is found that the PMLG with Mild Steel and Somaloy, respectively give larger induced voltage. Moreover, as the translator speed increase the induced voltage increased.

An investigation of shoulder forces in active shoulder tackles in rugby union football.

Science.gov (United States)

Usman, Juliana; McIntosh, Andrew S; Fréchède, Bertrand

2011-11-01

In rugby union football the tackle is the most frequently executed skill and one most associated with injury, including shoulder injury to the tackler. Despite the importance of the tackle, little is known about the magnitude of shoulder forces in the tackle and influencing factors. The objectives of the study were to measure the shoulder force in the tackle, as well as the effects of shoulder padding, skill level, side of body, player size, and experimental setting on shoulder force. Experiments were conducted in laboratory and field settings using a repeated measures design. Thirty-five participants were recruited to the laboratory and 98 to the field setting. All were male aged over 18 years with rugby experience. The maximum force applied to the shoulder in an active shoulder tackle was measured with a custom built forceplate incorporated into a 45 kg tackle bag. The overall average maximum shoulder force was 1660 N in the laboratory and 1997 N in the field. This difference was significant. The shoulder force for tackling without shoulder pads was 1684 N compared to 1635 N with shoulder pads. There was no difference between the shoulder forces on the dominant and non-dominant sides. Shoulder force reduced with tackle repetition. No relationship was observed between player skill level and size. A substantial force can be applied to the shoulder and to an opponent in the tackle. This force is within the shoulder's injury tolerance range and is unaffected by shoulder pads. Copyright © 2011 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Forces, energetics, and dynamics of conjugated-carbon ring tethers adhered to CNTs: a computational investigation.

Science.gov (United States)

Filla, Nicholas; Ramasamy, Ramaraja; Wang, Xianqiao

2018-04-25

The strength and nature of the interactions between carbon nanotubes (CNTs) and molecular tethers plays a vital role in technology such as CNT-enzyme sensors. Tethers that attach noncovalently to CNTs are ideal for retaining the electrical properties of the CNTs since they do not degrade the CNT surface and effect its electrical conductivity. However, leaching due to weak CNT-tether attachment is very common when using noncovalent tethers, and this has limited their use in commercial products including biosensors. Thus, understanding the fundamental mechanics governing the strength of CNT-tether adhesion is crucial for the design of highly sensitive, viable sensors. Here, we computationally investigate the adhesion strength of CNT-tether complexes with 8 different tethering molecules designed to adhere noncovalently to the CNT surface. We study the effects of CNT diameter, CNT chirality, and the size/geometry of the tethering molecule on the adhesion energy and force. Our results show an asymptotic relationship between adhesion strength and CNT diameter. Calculations show that noncovalent tethers tested here can reach adhesion forces and energies that are up to 21% and 54% of the strength of the carbon-carbon single bond force and bond energy respectively. We anticipate our results will help guide CNT-enzyme sensor design to produce sensors with high sensitivity and minimal leaching.

Investigation of internal feedback in hearing aids

DEFF Research Database (Denmark)

Friis, Lars

2009-01-01

with vibroacoustic transmission from the receiver to the microphones often occur during the use of hearing aids. This transmission causes feedback at certain critical gain levels where it produces a loud uncomfortable squealing. Consequently feedback often constitutes the limiting factor for the maximum obtainable...... gain in the hearing aid and it therefore represents a critical design problem. Feedback in hearing aids is usually divided into external and internal feedback. External feedback is caused by the leakage of sound from the ear canal whereas internal feedback is due to transmission of sound and vibrations...... internally in the hearing aid. As a result of reducing the size of hearing aids, manufacturers have experienced an increase in internal feedback problems. The main objective of the present thesis is therefore to examine the vibroacoustic mechanisms responsible for internal feedback in hearing aids...

Upper Limb Asymmetry in the Sense of Effort Is Dependent on Force Level

Directory of Open Access Journals (Sweden)

Diane E. Adamo

2017-04-01

Full Text Available Previous studies have shown that asymmetries in upper limb sensorimotor function are dependent on the source of sensory and motor information, hand preference and differences in hand strength. Further, the utilization of sensory and motor information and the mode of control of force may differ between the right hand/left hemisphere and left hand/right hemisphere systems. To more clearly understand the unique contribution of hand strength and intrinsic differences to the control of grasp force, we investigated hand/hemisphere differences when the source of force information was encoded at two different force levels corresponding to a 20 and 70% maximum voluntary contraction or the right and left hand of each participant. Eleven, adult males who demonstrated a stronger right than left maximum grasp force were requested to match a right or left hand 20 or 70% maximal voluntary contraction reference force with the opposite hand. During the matching task, visual feedback corresponding to the production of the reference force was available and then removed when the contralateral hand performed the match. The matching relative force error was significantly different between hands for the 70% MVC reference force but not for the 20% MVC reference force. Directional asymmetries, quantified as the matching force constant error, showed right hand overshoots and left undershoots were force dependent and primarily due to greater undershoots when matching with the left hand the right hand reference force. Findings further suggest that the interaction between internal sources of information, such as efferent copy and proprioception, as well as hand strength differences appear to be hand/hemisphere system dependent. Investigations of force matching tasks under conditions whereby force level is varied and visual feedback of the reference force is available provides critical baseline information for building effective interventions for asymmetric (stroke

British Students' Perceptions of Ethical Issues in International Marketing: An Empirical Investigation.

Science.gov (United States)

Amin, Sammy G.

1996-01-01

A survey investigated 122 British business students' perceptions of ethics in international marketing practices, particularly as they are affected by demographic characteristics. In response to 12 specific scenarios, students indicated relatively liberal attitudes. Implications for global marketing specialists and for business education are…

Hydrogen disposal investigation for the Space Shuttle launch complex at Vandenberg Air Force Base

Science.gov (United States)

Breit, Terry J.; Elliott, George

1987-01-01

The concern of an overpressure condition on the aft end of the Space Shuttle caused by ignition of unburned hydrogen being trapped in the Space Shuttle Main Engine exhaust duct at the Vandenberg AFB launch complex has been investigated for fifteen months. Approximately twenty-five concepts have been reviewed, with four concepts being thoroughly investigated. The four concepts investigated were hydrogen burnoff ignitors (ignitors located throughout the exhaust duct to continuously ignite any unburned hydrogen), jet mixing (utilizing large volumes of high pressure air to ensure complete combustion of the hydrogen), steam inert (utilizing flashing hot water to inert the duct with steam) and open duct concept (design an open duct or above grade J-deflector to avoid trapping hydrogen gas). Extensive studies, analyses and testing were performed at six test sites with technical support from twenty-two major organizations. In December 1986, the Air Force selected the steam inert concept to be utilized at the Vandenberg launch complex and authorized the design effort.

An investigation of the international literature on nurse practitioner private practice models.

Science.gov (United States)

Currie, J; Chiarella, M; Buckley, T

2013-12-01

To investigate and synthesize the international literature surrounding nurse practitioner (NP) private practice models in order to provide an exposition of commonalities and differences. NP models of service delivery have been established internationally and most are based in the public healthcare system. In recent years, opportunities for the establishment of NP private practice models have evolved, facilitated by changes in legislation and driven by identification of potential patient need. To date, NP private practice models have received less attention in the literature and, to the authors' knowledge, this is the first international investigation of NP private practice models. Integrative literature review. A literature search was undertaken in October 2012. Database sources utilized included Medical Literature Analyses and Retrieval (MEDLINE), the Cumulative Index of Nursing and Allied Health Literature (CINAHL), ProQuest, Scopus and the Cochrane Database of Systematic Reviews (CDSR). The grey literature was also searched. The following Medical Subject Headings (MeSH) and search terms used both individually and in combination included nurse practitioners; private practice; joint practice; collaboration; and insurance, health and reimbursement. Once literature had been identified, a thematic analysis was undertaken to extract themes. Thirty manuscripts and five publications from the grey literature were included in the final review. Private practice NP roles were identified in five countries, with the majority of the literature emanating from the USA. The thematic analysis resulted in the identification of five themes: reimbursement, collaborative arrangements, legislation, models of care and acceptability. Proportionally, there are very few NPs engaged in private practice internationally. The most common NP private practice models were community based, with NPs working in clinic settings, either alone or with other health professionals. Challenges in the

A framework for remission in SLE: consensus findings from a large international task force on definitions of remission in SLE (DORIS).

Science.gov (United States)

van Vollenhoven, Ronald; Voskuyl, Alexandre; Bertsias, George; Aranow, Cynthia; Aringer, Martin; Arnaud, Laurent; Askanase, Anca; Balážová, Petra; Bonfa, Eloisa; Bootsma, Hendrika; Boumpas, Dimitrios; Bruce, Ian; Cervera, Ricard; Clarke, Ann; Coney, Cindy; Costedoat-Chalumeau, Nathalie; Czirják, László; Derksen, Ronald; Doria, Andrea; Dörner, Thomas; Fischer-Betz, Rebecca; Fritsch-Stork, Ruth; Gordon, Caroline; Graninger, Winfried; Györi, Noémi; Houssiau, Frédéric; Isenberg, David; Jacobsen, Soren; Jayne, David; Kuhn, Annegret; Le Guern, Veronique; Lerstrøm, Kirsten; Levy, Roger; Machado-Ribeiro, Francinne; Mariette, Xavier; Missaykeh, Jamil; Morand, Eric; Mosca, Marta; Inanc, Murat; Navarra, Sandra; Neumann, Irmgard; Olesinska, Marzena; Petri, Michelle; Rahman, Anisur; Rekvig, Ole Petter; Rovensky, Jozef; Shoenfeld, Yehuda; Smolen, Josef; Tincani, Angela; Urowitz, Murray; van Leeuw, Bernadette; Vasconcelos, Carlos; Voss, Anne; Werth, Victoria P; Zakharova, Helena; Zoma, Asad; Schneider, Matthias; Ward, Michael

2017-03-01

Treat-to-target recommendations have identified 'remission' as a target in systemic lupus erythematosus (SLE), but recognise that there is no universally accepted definition for this. Therefore, we initiated a process to achieve consensus on potential definitions for remission in SLE. An international task force of 60 specialists and patient representatives participated in preparatory exercises, a face-to-face meeting and follow-up electronic voting. The level for agreement was set at 90%. The task force agreed on eight key statements regarding remission in SLE and three principles to guide the further development of remission definitions:1. Definitions of remission will be worded as follows: remission in SLE is a durable state characterised by …………………. (reference to symptoms, signs, routine labs).2. For defining remission, a validated index must be used, for example, clinical systemic lupus erythematosus disease activity index (SLEDAI)=0, British Isles lupus assessment group (BILAG) 2004 D/E only, clinical European consensus lupus outcome measure (ECLAM)=0; with routine laboratory assessments included, and supplemented with physician's global assessment.3. Distinction is made between remission off and on therapy: remission off therapy requires the patient to be on no other treatment for SLE than maintenance antimalarials; and remission on therapy allows patients to be on stable maintenance antimalarials, low-dose corticosteroids (prednisone ≤5 mg/day), maintenance immunosuppressives and/or maintenance biologics.The task force also agreed that the most appropriate outcomes (dependent variables) for testing the prognostic value (construct validity) of potential remission definitions are: death, damage, flares and measures of health-related quality of life. The work of this international task force provides a framework for testing different definitions of remission against long-term outcomes. Published by the BMJ Publishing Group Limited. For

Wind Forces on Container Ships

DEFF Research Database (Denmark)

Andersen, Ingrid Marie Vincent

2012-01-01

An investigation of the wind forces acting on a 9,000+ TEU container ship has been carried out through a series of wind tunnel tests. It was investigated how the wind forces depend on the container configuration on the deck using a 1:450 scale model and a series of appropriate container...... are presented as nondimensional coefficients. It is concluded, that the measured forces and moment depend on the container configuration on deck, and the results may provide a general idea of how the magnitude of the wind forces is affected by a given container stacking configuration on a similar container ship....

Effect of Buoyancy on Forced Convection Heat Transfer in Vertical Channels - a Literature Survey

Energy Technology Data Exchange (ETDEWEB)

Bhattacharyya, A

1965-03-15

This report contains a short resume of the available information from various sources on the effect of free convection flow on forced convection heat transfer in vertical channels. Both theoretical and experimental investigations are included. Nearly all of the theoretical investigations are concerned with laminar flow with or without internal heat generation. More consistent data are available for upward flow than for downward flow. Curves are presented to determine whether free convection or forced convection mode of heat transfer is predominant for a particular Reynolds number and Rayleigh number. At Re{sub b} > 10{sup 5} free convection effects are negligible. Downward flow through a heated channel at low Reynolds number is unstable. Under similar conditions the overall heat transfer coefficient for downward flow tends to be higher than that for upward flow.

Thermal investigation of lithium-ion battery module with different cell arrangement structures and forced air-cooling strategies

International Nuclear Information System (INIS)

Wang, Tao; Tseng, K.J.; Zhao, Jiyun; Wei, Zhongbao

2014-01-01

Highlights: • Three-dimensional CFD model with forced air cooling are developed for battery modules. • Impact of different air cooling strategies on module thermal characteristics are investigated. • Impact of different model structures on module thermal responses are investigated. • Effect of inter-cell spacing on cell thermal characteristics are also studied. • The optimal battery module structure and air cooling strategy is recommended. - Abstract: Thermal management needs to be carefully considered in the lithium-ion battery module design to guarantee the temperature of batteries in operation within a narrow optimal range. This article firstly explores the thermal performance of battery module under different cell arrangement structures, which includes: 1 × 24, 3 × 8 and 5 × 5 arrays rectangular arrangement, 19 cells hexagonal arrangement and 28 cells circular arrangement. In addition, air-cooling strategies are also investigated by installing the fans in the different locations of the battery module to improve the temperature uniformity. Factors that influence the cooling capability of forced air cooling are discussed based on the simulations. The three-dimensional computational fluid dynamics (CFD) method and lumped model of single cell have been applied in the simulation. The temperature distributions of batteries are quantitatively described based on different module patterns, fan locations as well as inter-cell distance, and the conclusions are arrived as follows: when the fan locates on top of the module, the best cooling performance is achieved; the most desired structure with forced air cooling is cubic arrangement concerning the cooling effect and cost, while hexagonal structure is optimal when focus on the space utilization of battery module. Besides, the optimized inter-cell distance in battery module structure has been recommended

Experimental Investigation of Piston Rings for Internal Combustion Engines

DEFF Research Database (Denmark)

Klit, Peder; Vølund, Anders

2008-01-01

absorbed in the bearing. Since the frictional forces are small compared to the rest of the acting forces the rig is designed such that the piston is fixed while the cylinder liner moves. This approach makes it simple to measure the parameters mentioned above by putting the instrumentation in the piston...

Fundamental investigation on interaction forces in bubble swarms and its application to the design of centrifugal separators

International Nuclear Information System (INIS)

Wisman, R.

1979-01-01

The present investigation deals with two aspects of gas-liquid flows, viz. interaction forces between the phases in bubble swarms and numerical description of rotating gas-liquid flows. The insight obtained was applied to the development of axial gas-liquid cyclones, as used i.a. as primary separators in nuclear boiling water reactors. (Auth.)

[Environmental investigation of ground water contamination at Wright- Patterson Air Force Base, Ohio]. Volume 4, Health and Safety Plan (HSP); Phase 1, Task 4 Field Investigation report: Draft

Energy Technology Data Exchange (ETDEWEB)

1991-10-01

This Health and Safety Plan (HSP) was developed for the Environmental Investigation of Ground-water Contamination Investigation at Wright-Patterson Air Force Base near Dayton, Ohio, based on the projected scope of work for the Phase 1, Task 4 Field Investigation. The HSP describes hazards that may be encountered during the investigation, assesses the hazards, and indicates what type of personal protective equipment is to be used for each task performed. The HSP also addresses the medical monitoring program, decontamination procedures, air monitoring, training, site control, accident prevention, and emergency response.

Proceedings of the IRI Task Force Activity 2002. 1. ed

International Nuclear Information System (INIS)

Radicella, S.M.

2003-06-01

This ICTP Internal Report contains the list of papers presented, activity reports and the write up of a number of presentations delivered during the International Reference Ionosphere (IRI) Task Force Activity 2002 which took place at the Abdus Salam ICTP during August 2002. The 2002 Task Force Activity is the ninth successful encounter of specialists organized by the URSI-Cospar IRI Working Group and the Aeronomy and Radiopropagation Laboratory of the Abdus Salam International Centre for Theoretical Physics of Trieste, Italy. The main topics of the meeting were ionosphere variability and topside ionosphere

Proceedings of the IRI Task Force Activity 2001

International Nuclear Information System (INIS)

Radicella, S.M.

2002-08-01

This ICTP Internal Report contains the list of papers presented, activity report and the write up of a number of presentations delivered during the International Reference Ionosphere (IRI) Task Force Activity 2001 which took place at the Abdus Salam ICTP during May 2001, particularly centred in the week from 21-25 May. The 2001 Task Force Activity is the eighth successful encounter of specialists organized by the URSI-Cospar IRI Working Group and the Aeronomy and Radiopropagation Laboratory of the Abdus Salam International Centre for Theoretical Physics of Trieste, Italy. This project continues the IRI Task Force Activities at the Abdus Salam International Centre for Theoretical Physics (ICTP) in Trieste, Italy. The primary focus of this activity was the development of a specification model for ionospheric variability. Such a model is high on the wish list of users of ionospheric models. Climatological models like IRI provide monthly mean values of ionospheric parameters. Understandably a satellite designer or operator needs to know not only the monthly average conditions but also the expected deviations from these mean values. The main discussions and presentations took place during the week 21-25 May. The format was similar to last year's activity with presentations and round-table discussions in the morning and follow-on work in small subgroups in front of computer terminals in the afternoon. This Proceedings contains also four papers of the previous IRI Task Force Activity which were omitted

Investigation of specific interactions between T7 promoter and T7 RNA polymerase by force spectroscopy using atomic force microscope.

Science.gov (United States)

Zhang, Xiaojuan; Yao, Zhixuan; Duan, Yanting; Zhang, Xiaomei; Shi, Jinsong; Xu, Zhenghong

2018-01-11

The specific recognition and binding of promoter and RNA polymerase is the first step of transcription initiation in bacteria and largely determines transcription activity. Therefore, direct analysis of the interaction between promoter and RNA polymerase in vitro may be a new strategy for promoter characterization, to avoid interference due to the cell's biophysical condition and other regulatory elements. In the present study, the specific interaction between T7 promoter and T7 RNA polymerase was studied as a model system using force spectroscopy based on atomic force microscope (AFM). The specific interaction between T7 promoter and T7 RNA polymerase was verified by control experiments, and the rupture force in this system was measured as 307.2 ± 6.7 pN. The binding between T7 promoter mutants with various promoter activities and T7 RNA polymerase was analyzed. Interaction information including rupture force, rupture distance and binding percentage were obtained in vitro , and reporter gene expression regulated by these promoters was also measured according to a traditional promoter activity characterization method in vivo Using correlation analysis, it was found that the promoter strength characterized by reporter gene expression was closely correlated with rupture force and the binding percentage by force spectroscopy. These results indicated that the analysis of the interaction between promoter and RNA polymerase using AFM-based force spectroscopy was an effective and valid approach for the quantitative characterization of promoters. © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

A New Protection Orientation and Framework for Refugees and Other Forced Migrants

Directory of Open Access Journals (Sweden)

James C. Simeon

2017-12-01

Full Text Available The unprecedented current “refugee crisis,” with its 65 million plus uprooted people, demands a new protection orientation and framework for refugees and other forced migrants that are focused on the “root causes” of refugeehood, non-international protracted armed conflict or civil war. It is argued that four essential reforms are required to the international refugee protection system to respond to the “root causes” of refugees in the world today. The first calls for broadening the definition of who is a refugee to include “war refugees” as found in the 1984 Cartagena Declaration and the 1969 Organization of African Unity (OAU Convention. The 1984 Cartagena Declaration is preferred because it has the most progressive and broadest legal definition of who is a refugee and, therefore, should be emulated by all regions and the UNHCR internationally. The second reform would be the adoption of the Cartagena Declaration decennial consultation process and its comprehensive Plan of Action by the UNHCR on a global basis. This process has proven to be a success in Latin America and ought to be adopted internationally to develop and to realize the progressive advancement of international protection for all persons who are fleeing persecution and armed conflict. The third major reform is to develop the capacity of the UN to be able to operate in the midst of an armed conflict situation in order to broker a ceasefire and, then, negotiate a peace agreement, particularly, in those situations where massed forced displacement has taken place or potentially could take place. The fourth reform calls for the UN to expand the Responsibility to Protect (R2P doctrine to incorporate massed forced displacement, in addition to, war crimes, crimes against humanity, ethnic cleansing, and, genocide. This further implies that mass forced displacement ought to be criminalized and made a serious international crime, not simply in the international humanitarian

How to orient the functional GroEL-SR1 mutant for atomic force microscopy investigations

International Nuclear Information System (INIS)

Schiener, Jens; Witt, Susanne; Hayer-Hartl, Manajit; Guckenberger, Reinhard

2005-01-01

We present high-resolution atomic force microscopy (AFM) imaging of the single-ring mutant of the chaperonin GroEL (SR-EL) from Escherichia coli in buffer solution. The native GroEL is generally unsuitable for AFM scanning as it is easily being bisected by forces exerted by the AFM tip. The single-ring mutant of GroEL with its simplified composition, but unaltered capability of binding substrates and the co-chaperone GroES, is a more suited system for AFM studies. We worked out a scheme to systematically investigate both the apical and the equatorial faces of SR-EL, as it binds in a preferred orientation to hydrophilic mica and hydrophobic highly ordered pyrolytic graphite. High-resolution topographical imaging and the interaction of the co-chaperone GroES were used to assign the orientations of SR-EL in comparison with the physically bisected GroEL. The usage of SR-EL facilitates single molecule studies on the folding cycle of the GroE system using AFM

Internal-external malalignment of the femoral component in kinematically aligned total knee arthroplasty increases tibial force imbalance but does not change laxities of the tibiofemoral joint.

Science.gov (United States)

Riley, Jeremy; Roth, Joshua D; Howell, Stephen M; Hull, Maury L

2018-06-01

The purposes of this study were to quantify the increase in tibial force imbalance (i.e. magnitude of difference between medial and lateral tibial forces) and changes in laxities caused by  2° and 4° of internal-external (I-E) malalignment of the femoral component in kinematically aligned total knee arthroplasty. Because I-E malalignment would introduce the greatest changes to the articular surfaces near 90° of flexion, the hypotheses were that the tibial force imbalance would be significantly increased near 90° flexion and that primarily varus-valgus laxity would be affected near 90° flexion. Kinematically aligned TKA was performed on ten human cadaveric knee specimens using disposable manual instruments without soft tissue release. One 3D-printed reference femoral component, with unmodified geometry, was aligned to restore the native distal and posterior femoral joint lines. Four 3D-printed femoral components, with modified geometry, introduced I-E malalignments of 2° and 4° from the reference component. Medial and lateral tibial forces were measured from 0° to 120° flexion using a custom tibial force sensor. Bidirectional laxities in four degrees of freedom were measured from 0° to 120° flexion using a custom load application system. Tibial force imbalance increased the greatest at 60° flexion where a regression analysis against the degree of I-E malalignment yielded sensitivities (i.e. slopes) of 30 N/° (medial tibial force > lateral tibial force) and 10 N/° (lateral tibial force > medial tibial force) for internal and external malalignments, respectively. Valgus laxity increased significantly with the 4° external component with the greatest increase of 1.5° occurring at 90° flexion (p < 0.0001). With the tibial component correctly aligned, I-E malalignment of the femoral component caused significant increases in tibial force imbalance. Minimizing I-E malalignment lowers the increase in the tibial force imbalance. By keeping

How weather impacts the forced climate response

Energy Technology Data Exchange (ETDEWEB)

Kirtman, Ben P. [University of Miami, Division of Meteorology and Physical Oceanography, Rosenstiel School for Atmospheric and Marine Science, Miami, FL (United States); Center for Ocean-Land-Atmosphere Studies, Calverton, MD (United States); Schneider, Edwin K.; Straus, David M. [George Mason University, Department of Atmospheric, Oceanic and Earth Sciences, Fairfax, VA (United States); Center for Ocean-Land-Atmosphere Studies, Calverton, MD (United States); Min, Dughong; Burgman, Robert [University of Miami, Division of Meteorology and Physical Oceanography, Rosenstiel School for Atmospheric and Marine Science, Miami, FL (United States)

2011-12-15

The new interactive ensemble modeling strategy is used to diagnose how noise due to internal atmospheric dynamics impacts the forced climate response during the twentieth century (i.e., 1870-1999). The interactive ensemble uses multiple realizations of the atmospheric component model coupled to a single realization of the land, ocean and ice component models in order to reduce the noise due to internal atmospheric dynamics in the flux exchange at the interface of the component models. A control ensemble of so-called climate of the twentieth century simulations of the Community Climate Simulation Model version 3 (CCSM3) are compared with a similar simulation with the interactive ensemble version of CCSM3. Despite substantial differences in the overall mean climate, the global mean trends in surface temperature, 500 mb geopotential and precipitation are largely indistinguishable between the control ensemble and the interactive ensemble. Large differences in the forced response; however, are detected particularly in the surface temperature of the North Atlantic. Associated with the forced North Atlantic surface temperature differences are local differences in the forced precipitation and a substantial remote rainfall response in the deep tropical Pacific. We also introduce a simple variance analysis to separately compare the variance due to noise and the forced response. We find that the noise variance is decreased when external forcing is included. In terms of the forced variance, we find that the interactive ensemble increases this variance relative to the control. (orig.)

Investigation into the behaviour of concrete anchored diaphragm walls under earthquake condition

International Nuclear Information System (INIS)

Saba, H. R.; Rahaii, A. R.

2003-01-01

Diaphragm walls are frequently used in civil Engineering projects. Considering the variety and important volume of consumed materials (concrete, anchors and soil), one of the important factors for design and construction of these walls, are their behaviour under different executive, and loading conditions. In this paper, various models of concrete diaphragms with different number of anchors and soil parameters under static and dynamic loading have been investigated using finite element method with nonlinear models. Results including the internal forces in diaphragm walls, variation of forces in the anchors, shape of the sliding surface and variation of pressure in soil are obtained and compared. An experimental tool with suitable measurement systems for determining the pressure and internal forces was designed and realised. Also with similitude and dimensional analyses, diaphragms with different number of anchors were built and set on the shaking table test and experimented under different accelograms. Finally results of nonlinear dynamic analysis were compared with experimental results

Air Force Health Study. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. First Followup Examination Results. Volume 1

Science.gov (United States)

1987-10-01

include actinic elastosis,,ape scars, disfigurement, excessive hair growth , and Peyronie’s disease. Severe chloracne is often accom- panied by acute...differences between the Ranch vii Hands and the Comparisons, and these differances vera not traditional indi- cators of dioxin-related disease. Both the...Investigation Dioxis* alo Sadmilfr-iis&R"Bn 05bi 40 ormang Air Force Nealta Study Morbidity * tG* 1 AI IA C8000 so *wow 4440" O*e*MV IVea =7Win ee-" * This

Force spectroscopy of collagen fibers to investigate their mechanical properties and structural organization.

Science.gov (United States)

Gutsmann, Thomas; Fantner, Georg E; Kindt, Johannes H; Venturoni, Manuela; Danielsen, Signe; Hansma, Paul K

2004-05-01

Tendons are composed of collagen and other molecules in a highly organized hierarchical assembly, leading to extraordinary mechanical properties. To probe the cross-links on the lower level of organization, we used a cantilever to pull substructures out of the assembly. Advanced force probe technology, using small cantilevers (length exponential increase in force and two different periodic rupture events, one with strong bonds (jumps in force of several hundred pN) with a periodicity of 78 nm and one with weak bonds (jumps in force of <7 pN) with a periodicity of 22 nm. We demonstrate a good correlation between the measured mechanical behavior of collagen fibers and their appearance in the micrographs taken with the atomic force microscope.

Atomic force microscopy investigation of the giant mimivirus

International Nuclear Information System (INIS)

Kuznetsov, Yuri G.; Xiao Chuan; Sun Siyang; Raoult, Didier; Rossmann, Michael; McPherson, Alexander

2010-01-01

Mimivirus was investigated by atomic force microscopy in its native state following serial degradation by lysozyme and bromelain. The 750-nm diameter virus is coated with a forest of glycosylated protein fibers of lengths about 140 nm with diameters 1.4 nm. Fibers are capped with distinctive ellipsoidal protein heads of estimated Mr = 25 kDa. The surface fibers are attached to the particle through a layer of protein covering the capsid, which is in turn composed of the major capsid protein (MCP). The latter is organized as an open network of hexagonal rings with central depressions separated by 14 nm. The virion exhibits an elaborate apparatus at a unique vertex, visible as a star shaped depression on native particles, but on defibered virions as five arms of 50 nm width and 250 nm length rising above the capsid by 20 nm. The apparatus is integrated into the capsid and not applied atop the icosahedral lattice. Prior to DNA release, the arms of the star disengage from the virion and it opens by folding back five adjacent triangular faces. A membrane sac containing the DNA emerges from the capsid in preparation for fusion with a membrane of the host cell. Also observed from disrupted virions were masses of distinctive fibers of diameter about 1 nm, and having a 7-nm periodicity. These are probably contained within the capsid along with the DNA bearing sac. The fibers were occasionally observed associated with toroidal protein clusters interpreted as processive enzymes modifying the fibers.

Seasonal variation of semidiurnal internal tides in the East/Japan Sea

Science.gov (United States)

Jeon, Chanhyung; Park, Jae-Hun; Varlamov, Sergey M.; Yoon, Jong-Hwan; Kim, Young Ho; Seo, Seongbong; Park, Young-Gyu; Min, Hong Sik; Lee, Jae Hak; Kim, Cheol-Ho

2014-05-01

The seasonal variation of semidiurnal internal tides in the East/Japan Sea was investigated using 25 month long output from a real-time ocean forecasting system. The z coordinate eddy-resolving high-resolution numerical model, called the RIAM ocean model, incorporates data assimilation that nudges temperature and salinity fields together with volume transport through the Korea Strait to produce realistic oceanic currents and stratification. In addition to atmospheric forcing, it includes tidal forcing of 16 major components along open boundaries. The model generates energetic semidiurnal internal tides around the northern entrance of the Korea Strait. Energy conversion from barotropic to baroclinic (internal) tides varies seasonally with maxima in September (ranging 0.48-0.52 GW) and minima in March (ranging 0.11-0.16 GW). This seasonal variation is induced by the seasonality in stratification near the southwestern East/Japan Sea. The propagation distance of the internal tides is associated with generation intensity and wavelength. From late summer to early winter, the semidiurnal internal tides travel relatively far from the generation region due to stratification changes; its energy dissipates less as a result of longer wavelengths. Our results suggest that spatiotemporal variation of internal-tide-induced mixing due to the seasonality in the generation, propagation, and dissipation of internal tides should be considered for a more realistic simulation of water masses and circulation in models of the East/Japan Sea.

Investigating the Impact of Cambridge International Assessments on U.S. Stakeholders: Student and Teacher Perceptions

Science.gov (United States)

Shaw, Stuart

2011-01-01

As part of the continuing program to study the impact of its international assessments, the University of Cambridge International Examinations ("Cambridge") has undertaken a series of studies investigating the impact on a range of US stakeholders. This paper reports on research designed to respond to a series of washback and impact…

Comparing internal and external drivers in the southern Benguela ...

African Journals Online (AJOL)

Comparing internal and external drivers in the southern Benguela and the southern and ... during the model fitting: internal forcing by means of the trophic flow controls ... and two kinds of external forcing, namely fishing and the environment.

Quantitative nanohistological investigation of scleroderma: an atomic force microscopy-based approach to disease characterization

Directory of Open Access Journals (Sweden)

Strange AP

2017-01-01

Full Text Available Adam P Strange,1 Sebastian Aguayo,1 Tarek Ahmed,1 Nicola Mordan,1 Richard Stratton,2 Stephen R Porter,3 Susan Parekh,4 Laurent Bozec1 1Department of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, 2Centre for Rheumatology and Connective Tissue Diseases, Royal Free Hospital, UCL Medical School, 3UCL Eastman Dental Institute, 4Department of Pediatrics, UCL Eastman Dental Institute, London, UK Abstract: Scleroderma (or systemic sclerosis, SSc is a disease caused by excess crosslinking of collagen. The skin stiffens and becomes painful, while internally, organ function can be compromised by the less elastic collagen. Diagnosis of SSc is often only possible in advanced cases by which treatment time is limited. A more detailed analysis of SSc may provide better future treatment options and information of disease progression. Recently, the histological stain picrosirius red showing collagen register has been combined with atomic force microscopy (AFM to study SSc. Skin from healthy individuals and SSc patients was biopsied, stained and studied using AFM. By investigating the crosslinking of collagen at a smaller hierarchical stage, the effects of SSc were more pronounced. Changes in morphology and Young’s elastic modulus were observed and quantified; giving rise to a novel technique, we have termed “quantitative nanohistology”. An increase in nanoscale stiffness in the collagen for SSc compared with healthy individuals was seen by a significant increase in the Young’s modulus profile for the collagen. These markers of stiffer collagen in SSc are similar to the symptoms experienced by patients, giving additional hope that in the future, nanohistology using AFM can be readily applied as a clinical tool, providing detailed information of the state of collagen. Keywords: rheumatology, adjunct diagnosis, picrosirius red, collagen, nanohistology

Dosimetry-based treatment planning for molecular radiotherapy: a summary of the 2017 report from the Internal Dosimetry Task Force

Directory of Open Access Journals (Sweden)

Caroline Stokke

2017-11-01

Full Text Available Abstract Background The European directive on basic safety standards (Council directive 2013/59 Euratom mandates dosimetry-based treatment planning for radiopharmaceutical therapies. The directive comes into operation February 2018, and the aim of a report produced by the Internal Dosimetry Task Force of the European Association of Nuclear Medicine is to address this aspect of the directive. A summary of the report is presented. Results A brief review of five of the most common therapy procedures is included in the current text, focused on the potential to perform patient-specific dosimetry. In the full report, 11 different therapeutic procedures are included, allowing additional considerations of effectiveness, references to specific literature on quantitative imaging and dosimetry, and existing evidence for absorbed dose-effect correlations for each treatment. Individualized treatment planning with tracer diagnostics and verification of the absorbed doses delivered following therapy is found to be scientifically feasible for almost all procedures investigated, using quantitative imaging and/or external monitoring. Translation of this directive into clinical practice will have significant implications for resource requirements. Conclusions Molecular radiotherapy is undergoing a significant expansion, and the groundwork for dosimetry-based treatment planning is already in place. The mandated individualization is likely to improve the effectiveness of the treatments, although must be adequately resourced.

Language and the International Context

Science.gov (United States)

Tonkin, Humphrey

1977-01-01

A discussion of the issue of unilinguism and linguistic pluralism on the international scene. The need for international communication where English is the dominant force and efforts to preserve cultural equality are seen as compelling reasons for promotion of an international language such as Esperanto. (AMH)

Investigation of the influence of vertical force on the contact between truck tyre and road using finite element analyses

Science.gov (United States)

Moisescu, Alexandra-Raluca; Anghelache, Gabriel

2017-10-01

In the modern context of automobile integration with the emerging technologies of the interconnected society, the interaction between tyre and road is an element of major importance for automobile safety systems such as the intelligent tyres, as well as for passenger comfort, fuel economy, environmental protection, infrastructure and vehicle durability. The tyre-road contact generates the distribution of forces exerted on each unit area in the contact patch, therefore the distribution of contact stresses on three orthogonal directions. The numerical investigation of stresses distribution in the contact patch requires the development of finite element models capable of accurately describing the interaction between tyre and rolling surface. The complex finite element model developed for the 11R22.5 truck tyre has been used for investigating the influence of vertical force on the distributions of contact stresses. In addition to these contributions, the paper presents aspects related to the simulation of truck tyre radial stiffness. The influence of tyre rolling has not been taken into consideration, as the purpose of the current research is the investigation of tyre-road contact in stationary conditions.

Results of assembly test of HTTR reactor internals

International Nuclear Information System (INIS)

Maruyama, S.; Saikusa, A.; Shiozawa, S.; Tsuji, N.; Miki, T.

1996-01-01

The assembly test of the HTTR actual reactor internals had been carried out at the works, prior to their installation in the actual reactor pressure vessel(RPV) at the construction site. The assembly test consists of several items such as examining fabricating precision of each component and alignment of piled-up structures, measuring circumferential coolant velocity profile in the passage between the simulated RPV and the reactor internals as well as under the support plates, measuring by-pass flow rate through gaps between the reactor internals, and measuring the binding force of the core restraint mechanism. Results of the test showed good performance of the HTTR reactor internals. Installation of the reactor internals in the actual RPV was started at the construction site of HTTR in April, 1995. In the installation process, main items of the assembly test at the works were repeated to investigate the reproducibility of installation. (author). 5 refs, 11 figs

Investigation into the Effect of Acoustic Radiation Force and Acoustic Streaming on Particle Patterning in Acoustic Standing Wave Fields

Directory of Open Access Journals (Sweden)

Shilei Liu

2017-07-01

Full Text Available Acoustic standing waves have been widely used in trapping, patterning, and manipulating particles, whereas one barrier remains: the lack of understanding of force conditions on particles which mainly include acoustic radiation force (ARF and acoustic streaming (AS. In this paper, force conditions on micrometer size polystyrene microspheres in acoustic standing wave fields were investigated. The COMSOL® Mutiphysics particle tracing module was used to numerically simulate force conditions on various particles as a function of time. The velocity of particle movement was experimentally measured using particle imaging velocimetry (PIV. Through experimental and numerical simulation, the functions of ARF and AS in trapping and patterning were analyzed. It is shown that ARF is dominant in trapping and patterning large particles while the impact of AS increases rapidly with decreasing particle size. The combination of using both ARF and AS for medium size particles can obtain different patterns with only using ARF. Findings of the present study will aid the design of acoustic-driven microfluidic devices to increase the diversity of particle patterning.

Investigation into the Effect of Acoustic Radiation Force and Acoustic Streaming on Particle Patterning in Acoustic Standing Wave Fields

Science.gov (United States)

Yang, Yanye; Ni, Zhengyang; Guo, Xiasheng; Luo, Linjiao; Tu, Juan; Zhang, Dong

2017-01-01

Acoustic standing waves have been widely used in trapping, patterning, and manipulating particles, whereas one barrier remains: the lack of understanding of force conditions on particles which mainly include acoustic radiation force (ARF) and acoustic streaming (AS). In this paper, force conditions on micrometer size polystyrene microspheres in acoustic standing wave fields were investigated. The COMSOL® Mutiphysics particle tracing module was used to numerically simulate force conditions on various particles as a function of time. The velocity of particle movement was experimentally measured using particle imaging velocimetry (PIV). Through experimental and numerical simulation, the functions of ARF and AS in trapping and patterning were analyzed. It is shown that ARF is dominant in trapping and patterning large particles while the impact of AS increases rapidly with decreasing particle size. The combination of using both ARF and AS for medium size particles can obtain different patterns with only using ARF. Findings of the present study will aid the design of acoustic-driven microfluidic devices to increase the diversity of particle patterning. PMID:28753955

A Parametric Investigation of Nozzle Planform and Internal/External Geometry at Transonic Speeds

Science.gov (United States)

Cler, Daniel L.

1995-01-01

An experimental investigation of multidisciplinary (scarfed trailing edge) nozzle divergent flap geometry was conducted at transonic speeds in the NASA Langley 16-Foot Transonic Tunnel. The geometric parameters investigated include nozzle planform, nozzle contouring location (internal and/or external), and nozzle area ratio (area ratio 1.2 and 2.0). Data were acquired over a range of Mach Numbers from 0.6 to 1.2, angle-of-attack from 0.0 degrees to 9.6 degrees and nozzle pressure ratios from 1.0 to 20.0. Results showed that increasing the rate of change internal divergence angle across the width of the nozzle or increasing internal contouring will decrease static, aeropropulsive and thrust removed drag performance regardless of the speed regime. Also, increasing the rate of change in boattail angle across the width of the nozzle or increasing external contouring will provide the lowest thrust removed drag. Scarfing of the nozzle trailing edges reduces the aeropropulsive performance for the most part and adversely affects the nozzle plume shape at higher nozzle pressure ratios thus increasing the thrust removed drag. The effects of contouring were primary in nature and the effects of planform were secondary in nature. Larger losses occur supersonically than subsonically when scarfing of nozzle trailing edges occurs. The single sawtooth nozzle almost always provided lower thrust removed drag than the double sawtooth nozzles regardless the speed regime. If internal contouring is required, the double sawtooth nozzle planform provides better static and aeropropulsive performance than the single sawtooth nozzle and if no internal contouring is required the single sawtooth provides the highest static and aeropropulsive performance.

Experimental investigation of natural convection induced by internal heat generation

International Nuclear Information System (INIS)

Tasaka, Y; Kudoh, Y; Takeda, Y; Yanagisawa, T

2005-01-01

Dilatation of a convection cell with respect to its Rayleigh number, one of the problems in internally heated convection, was quantitatively investigated by analyzing temperature field in a cell. The temperature field visualized by a thermo-chromic liquid crystal (TLC) expresses the cell dilatation. A calibration system was developed to convert the visualized photographs of the temperature field to the temperature field. A calibration curve correlating color information extracted from the photograph and temperature was determined from the approximately linear temperature distribution in the horizontal fluid layer using the hue method. Photos taken at various internal Rayleigh numbers were converted to the temperature field by the obtained curve. Extracting individual cells from a temperature field achieves a quantitative expression of the cell dilatation as the variation of the wavenumber of the cell with Rayleigh number increases. The temperature profile in a cell shows that high temperature areas appear at the apexes of the cell, largely different from the profile obtained by linear theory

Investigation of lateral forces in dynamic mode using combined AFM/STM

OpenAIRE

Atabak, Mehrdad

2007-01-01

Ankara : The Department of Physics and The Institute of Engineering and Science of Bilkent University, 2007. Thesis (Ph.D.) -- Bilkent University, 2007. Includes bibliographical references leaves 114-126. In this Ph.D. work, we constructed a ¯ber optic interferometer based non-contact Atomic Force Microscope (nc-AFM) combined with Scanning Tunneling Micro- scope(STM) to study lateral force interactions on Si(111)-(77) surface. The in- terferometer has been built in such a wa...

Atomic force microscopy and nanoindentation investigation of polydimethylsiloxane elastomeric substrate compliancy for various sputtered thin film morphologies.

Science.gov (United States)

Maji, Debashis; Das, Soumen

2018-03-01

Crack free electrically continuous metal thin films over soft elastomeric substrates play an integral part in realization of modern day flexible bioelectronics and biosensors. Under nonoptimized deposition conditions, delamination, and/or cracking of the top film as well as the underlying soft substrate hinders optimal performance of these devices. Hence it is very important to understand and control not only the various deposition factors like power, time, or deposition pressure but also investigate the various interfacial physics playing a critical role in assuring thin film adhesion and substrate compliancy. In the present study, various nanomechanical information of the underlying substrate, namely, crack profile, average roughness, Young's modulus, and adhesion force were studied for uncracked and cracked polydimethylsiloxane (PDMS) surfaces along with pristine and conventional plasma treated PDMS samples as control. Quantification of the above parameters were done using three-dimensional surface profiler, scanning electron microscopy, nanoindentation, and atomic force microscopy techniques to elucidate the modulus range, average roughness, and adhesion force. Comparative analysis with control revealed remarkable similarity between increased modulus values, increased surface roughness, and reduced adhesion force accounting for reduced substrate compliancy and resulting in film cracking or buckling which are critical for development of various bioflexible devices. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 725-737, 2018. © 2017 Wiley Periodicals, Inc.

STRONG POINTS AND INTERNAL AND EXTERNAL VULNERABILITIES OF THE MILITARY COMMUNICATIONS AND INFORMATICS SYSTEMS AND NETWORKS DEVELOPED IN THE ROMANIAN ARMED FORCES UNDER THE CIRCUMSTANCES OF THE CURRENT SECURITY CHALLENGES

Directory of Open Access Journals (Sweden)

Constantin MINCU

2015-12-01

Full Text Available The author briefly presents a series of recent aspects in the current geopolitical context regarding some strong points as well as internal and external vulnerabilities of the military communication and informatics systems and networks developed in the Romanian Armed Forces since 1997. In the second section we referred to the evolutions in austerity and hostility conditions of the main operational and technical sequels of Romanian Armed Forces Transmissions System - STAR (RTP/RMNC. Furthermore, we presented some strong points of the achieved systems and principles taken into account along the modernization and transformation effort (regarding the NATO criteria and requirements, as well as their internal and external vulnerabilities identified following a thorough analysis.

iCub Whole-body Control through Force Regulation on Rigid Noncoplanar Contacts

Directory of Open Access Journals (Sweden)

Francesco eNori

2015-03-01

Full Text Available This paper details the implementation on the humanoid robot iCub of state-of-the-art algorithms for whole-body control. We regulate the forces between the robot and its surrounding environment to stabilize a desired robot posture. We assume that the forces and torques are exerted on rigid contacts. The validity of this assumption is guaranteed by constraining the contact forces and torques, e.g. the contact forces must belong to the associated friction cones. The implementation of this control strategy requires to estimate the external forces acting on the robot, and the internal joint torques. We then detail algorithms to obtain these estimations when using a robot with an iCub-like sensor set, i.e. distributed six-axis force-torque sensors and whole-body tactile sensors. A general theory for identifying the robot inertial parameters is also presented. From an actuation standpoint, we show how to implement a joint torque control in the case of DC brushless motors. In addition, the coupling mechanism of the iCub torso is investigated. The soundness of the entire control architecture is validated in a real scenario involving the robot iCub balancing and making contacts at both arms.

Current and Future Decadal Trends in the Oceanic Carbon Uptake Are Dominated by Internal Variability

Science.gov (United States)

Li, Hongmei; Ilyina, Tatiana

2018-01-01

We investigate the internal decadal variability of the ocean carbon uptake using 100 ensemble simulations based on the Max Planck Institute Earth system model (MPI-ESM). We find that on decadal time scales, internal variability (ensemble spread) is as large as the forced temporal variability (ensemble mean), and the largest internal variability is found in major carbon sink regions, that is, the 50-65°S band of the Southern Ocean, the North Pacific, and the North Atlantic. The MPI-ESM ensemble produces both positive and negative 10 year trends in the ocean carbon uptake in agreement with observational estimates. Negative decadal trends are projected to occur in the future under RCP4.5 scenario. Due to the large internal variability, the Southern Ocean and the North Pacific require the most ensemble members (more than 53 and 46, respectively) to reproduce the forced decadal trends. This number increases up to 79 in future decades as CO2 emission trajectory changes.

Theoretical and experimental investigation on internal reflectors in a single-slope solar still

International Nuclear Information System (INIS)

Karimi Estahbanati, M.R.; Ahsan, Amimul; Feilizadeh, Mehrzad; Jafarpur, Khosrow; Ashrafmansouri, Seyedeh-Saba; Feilizadeh, Mansoor

2016-01-01

Highlights: • The effect of installing an internal reflector in solar stills is investigated. • A mathematical model is presented which takes into account the effect of all walls. • The model is validated with the experimental data. • The internal reflector can increase yearly distillate production by 34%. • Cloud factor significantly decreases the effect of internal reflector. - Abstract: This study investigated the effect of an internal reflector (IR) on the productivity of a single-slope solar still (during the summer and winter) experimentally and theoretically. A mathematical model was presented which took into account the effect of all walls (north, south, west and east) of the still on the amount of received solar radiation to brine, and the model was validated with the experimental data. The model can calculate the yield of the still with and without IR on various walls. The results show that the simultaneous use of IR on front and side walls enhances the still’s efficiency by 18%. However, installation of an IR on the back wall can increase the annual efficiency by 22%. The installation of IRs on all walls in comparison to a still without IR can increase the distillate production at winter, summer and the entire year by 65%, 22% and 34%, respectively. Furthermore, the effect of cloud factor on the installation of IRs on all walls was examined, and the results indicate that the increasing the cloud factor decreases the influence of IRs significantly.

Three-nucleon forces and the trinucleon bound states

International Nuclear Information System (INIS)

Friar, J.L.; Frois, B.

1986-04-01

A summary of the bound-state working group session of the ''International Symposium on the Three-Body Force in the Three-Nucleon System'' is presented. The experimental evidence for three-nucleon forces has centered on two ground state properties: the tritium binding energy and the trinucleon form factors. Both are discussed

Neurology and international organizations.

Science.gov (United States)

Mateen, Farrah J

2013-07-23

A growing number of international stakeholders are engaged with neurologic diseases. This article provides a brief overview of important international stakeholders in the practice of neurology, including global disease-specific programs, United Nations agencies, governmental agencies with international influence, nongovernmental organizations, international professional organizations, large private donors, private-public partnerships, commercial interests, armed forces, and universities and colleges. The continued engagement of neurologists is essential for the growing number of international organizations that can and should incorporate neurologic disease into their global agendas.

Investigation of Body Force Effects on Flow Boiling Critical Heat Flux

Science.gov (United States)

Zhang, Hui; Mudawar, Issam; Hasan, Mohammad M.

2002-01-01

The bubble coalescence and interfacial instabilities that are important to modeling critical heat flux (CHF) in reduced-gravity systems can be sensitive to even minute body forces. Understanding these complex phenomena is vital to the design and safe implementation of two-phase thermal management loops proposed for space and planetary-based thermal systems. While reduced gravity conditions cannot be accurately simulated in 1g ground-based experiments, such experiments can help isolate the effects of the various forces (body force, surface tension force and inertia) which influence flow boiling CHF. In this project, the effects of the component of body force perpendicular to a heated wall were examined by conducting 1g flow boiling experiments at different orientations. FC-72 liquid was boiled along one wall of a transparent rectangular flow channel that permitted photographic study of the vapor-liquid interface at conditions approaching CHF. High-speed video imaging was employed to capture dominant CHF mechanisms. Six different CHF regimes were identified: Wavy Vapor Layer, Pool Boiling, Stratification, Vapor Counterflow, Vapor Stagnation, and Separated Concurrent Vapor Flow. CHF showed great sensitivity to orientation for flow velocities below 0.2 m/s, where very small CHF values where measured, especially with downflow and downward-facing heated wall orientations. High flow velocities dampened the effects of orientation considerably. Figure I shows representative images for the different CHF regimes. The Wavy Vapor Layer regime was dominant for all high velocities and most orientations, while all other regimes were encountered at low velocities, in the downflow and/or downward-facing heated wall orientations. The Interfacial Lift-off model was modified to predict the effects of orientation on CHF for the dominant Wavy Vapor Layer regime. The photographic study captured a fairly continuous wavy vapor layer travelling along the heated wall while permitting liquid

An Investigation of the Internal Structure of the Biggs Study Process Questionnaire.

Science.gov (United States)

Watkins, David; Hattie, John

1980-01-01

Results of an Australian study of the Biggs Study Process Questionnaire (SPQ) are presented. The purposes of the research were to: (1) re-examine the SPQ's internal consistency; (2) explore dimensionality of the SPQ scales; and (3) investigate validity of Bigg's model of the study process complex through factor analysis. (Author/GK)

Investigation of a cuboidal permanent magnet’s force exerted on a robotic capsule

Directory of Open Access Journals (Sweden)

Yang W

2014-08-01

Full Text Available Wan’an Yang,1 Chengbing Tang,2 Fengqing Qin1 1School of Computer and Information Engineering, Yibin University, Yibin, 2CNPC Chuanqing Geophysical Prospecting Company Research Center Computer Department, Chengdu, Sichuan, People’s Republic of China Abstract: To control and drive a robotic capsule accurately from outside a patient’s body, we present a schema in which the capsule enclosing the imaging device, circuits, batteries, etc is looped by a permanent magnet ring that acts as an actuator. A cuboidal permanent magnet situated outside the patient's body attracts or pushes the magnet ring from different directions to make the capsule move or rotate. A mathematic model of attractive or repulsive force that the cuboidal magnet exerts on the magnet ring is presented for accurate calculation of force. The experiments showed that the measuring force was in agreement with the theoretical one, and the relations between the dimensions of the cuboidal magnet and force are useful to produce a cuboidal magnet with optimal shape to get appropriate force. Keywords: control and drive, robotic capsule, permanent magnet ring, optimal dimension, force model

A numerical investigation of flow around octopus-like arms: near-wake vortex patterns and force development.

Science.gov (United States)

Kazakidi, A; Vavourakis, V; Tsakiris, D P; Ekaterinaris, J A

2015-01-01

The fluid dynamics of cephalopods has so far received little attention in the literature, due to their complexity in structure and locomotion. The flow around octopuses, in particular, can be complicated due to their agile and dexterous arms, which frequently display some of the most diverse mechanisms of motion. The study of this flow amounts to a specific instance of the hydrodynamics problem for rough tapered cylinder geometries. The outstanding manipulative and locomotor skills of octopuses could inspire the development of advanced robotic arms, able to operate in fluid environments. Our primary aim was to study the hydrodynamic characteristics of such bio-inspired robotic models and to derive the hydrodynamic force coefficients as a concise description of the vortical flow effects. Utilizing computational fluid dynamic methods, the coefficients were computed on realistic morphologies of octopus-like arm models undergoing prescribed solid-body movements; such motions occur in nature for short durations in time, e.g. during reaching movements and exploratory behaviors. Numerical simulations were performed on translating, impulsively rotating, and maneuvering arms, around which the flow field structures were investigated. The results reveal in detail the generation of complex vortical flow structures around the moving arms. Hydrodynamic forces acting on a translating arm depend on the angle of incidence; forces generated during impulsive rotations of the arms are independent of their exact morphology and the angle of rotation; periodic motions based on a slow recovery and a fast power stroke are able to produce considerable propulsive thrust while harmonic motions are not. Parts of these results have been employed in bio-inspired models of underwater robotic mechanisms. This investigation may further assist elucidating the hydrodynamics underlying aspects of octopus locomotion and exploratory behaviors.

Attentional Focusing Instructions and Force Production

Directory of Open Access Journals (Sweden)

David C Marchant

2011-01-01

Full Text Available Research progress assessing the role of attentional focusing instructions on skill acquisition and performance has lead researchers to apply this approach to force production tasks. Initial converging evidence indicates that force production tasks are sensitive to verbal instruction; externally focused instructions (onto movement outcomes, or onto the object force is being exerted against are shown to be more beneficial than internally focused instructions (focusing attention onto the movements being executed. These benefits are observed for maximal and accurate force production, as well as the maintenance of force production in prolonged tasks. A range of mechanisms are identified supporting the proposal that an external focus promotes movement efficiency in line with energy and effort conservation. Future research is required to assess how this developing body of work interacts with the broader understanding of psychological and physiological factors implicated in the effective production, maintenance and limitation of maximal or sub-maximal forces.

Preventing nuclear terrorism: the report and papers of the International Task Force on Prevention of Nuclear Terrorism

International Nuclear Information System (INIS)

Leventhal, P.; Alexander, Y.

1987-01-01

The International Task Force on Prevention of Nuclear Terrorism, formed in 1985 under the Nuclear Control Institute, commissioned 26 studies and produced an extensive report on the problem and prevention of nuclear terrorism, Part I of this book is the full report, and part II contains the individual studies under two section: (A) Defining the Threat (8 studies); and (B) Strategies for Dealing with the Threat (18 studies). Detailed recommendations are made, in many of the studies, for better protection of nuclear weapons, materials, and facilities; greater cooperation among national intelligence agencies; tighter controls on nuclear transfers; more effective arms control initiatives; and emergency management programs. A separate abstract was prepared for the report and each of the 26 studies

The Law of Force or The Force of Law: Does Following The Rule of Law Assist Security Forces in Defeating an Armed Insurgency?

Science.gov (United States)

2012-06-08

and Policy in International Relations (Spring): 40-79 Arendt , Hannah . 1963. On revolution. New York: Viking Cohen, Eliot A., John Horvath, and...conditions, where the armed forces can be trusted to obey the civil authorities” ( Arendt 1965, 40). This is especially the case in countries where

An international point source outbreak of typhoid fever: a European collaborative investigation*

Science.gov (United States)

Stanwell-Smith, R. E.; Ward, L. R.

1986-01-01

A point source outbreak of Salmonella typhi, degraded Vi-strain 22, affecting 32 British visitors to Kos, Greece, in 1983 was attributed by a case—control study to the consumption of a salad at one hotel. This represents the first major outbreak of typhoid fever in which a salad has been identified as the vehicle. The source of the infection was probably a carrier in the hotel staff. The investigation demonstrates the importance of national surveillance, international cooperation, and epidemiological methods in the investigation and control of major outbreaks of infection. PMID:3488842

Bubble dynamics in microchannels: inertial and capillary migration forces

Science.gov (United States)

Rivero-Rodriguez, Javier; Scheid, Benoit

2018-05-01

This work focuses on the dynamics of a train of unconfined bubbles flowing in microchan- nels. We investigate the transverse position of a train of bubbles, its velocity and the associated pressure drop when flowing in a microchannel depending on the internal forces due to viscosity, inertia and capillarity. Despite the small scales of the system, inertia, referred to as inertial migration force, play a crucial role in determining the transverse equilibrium position of the bubbles. Beside inertia and viscosity, other effects may also affect the transverse migration of bubbles such as the Marangoni surface stresses and the surface deformability. We look at the influence of surfactants in the limit of infinite Marangoni effect which yields rigid bubble interface. The resulting migration force may balance external body forces if present such as buoyancy, Dean or magnetic ones. This balance not only determines the transverse position of the bubbles but, consequently, the surrounding flow structure, which can be determinant for any mass/heat transfer process involved. Finally, we look at the influence of the bubble deformation on the equilibrium position and compare it to the inertial migration force at the centred position, explaining the stable or unstable character of this position accordingly. A systematic study of the influence of the parameters - such as the bubble size, uniform body force, Reynolds and capillary numbers - has been carried out using numerical simulations based on the Finite Element Method, solving the full steady Navier-Stokes equations and its asymptotic counterpart for the limits of small Reynolds and/or capillary numbers.

Investigating Move Structure of English Applied Linguistics Research Article Discussions Published in International and Thai Journals

Science.gov (United States)

Amnuai, Wirada; Wannaruk, Anchalee

2013-01-01

This study investigates the rhetorical move structure of English applied linguistic research article Discussions published in Thai and international journals. Two corpora comprising of 30 Thai Discussions and 30 international Discussions were analyzed using Yang & Allison's (2003) move model. Based on the analysis, both similarities and…

World health organization perspective on implementation of International Health Regulations.

Science.gov (United States)

Hardiman, Maxwell Charles

2012-07-01

In 2005, the International Health Regulations were adopted at the 58th World Health Assembly; in June 2007, they were entered into force for most countries. In 2012, the world is approaching a major 5-year milestone in the global commitment to ensure national capacities to identify, investigate, assess, and respond to public health events. In the past 5 years, existing programs have been boosted and some new activities relating to International Health Regulations provisions have been successfully established. The lessons and experience of the past 5 years need to be drawn upon to provide improved direction for the future.

Capillary force on a tilted cylinder: Atomic Force Microscope (AFM) measurements.

Science.gov (United States)

Kosgodagan Acharige, Sébastien; Laurent, Justine; Steinberger, Audrey

2017-11-01

The capillary force in situations where the liquid meniscus is asymmetric, such as the one around a tilted object, has been hitherto barely investigated even though these situations are very common in practice. In particular, the capillary force exerted on a tilted object may depend on the dipping angle i. We investigate experimentally the capillary force that applies on a tilted cylinder as a function of its dipping angle i, using a home-built tilting Atomic Force Microscope (AFM) with custom made probes. A micrometric-size rod is glued at the end of an AFM cantilever of known stiffness, whose deflection is measured when the cylindrical probe is dipped in and retracted from reference liquids. We show that a torque correction is necessary to understand the measured deflection. We give the explicit expression of this correction as a function of the probes' geometrical parameters, so that its magnitude can be readily evaluated. The results are compatible with a vertical capillary force varying as 1/cosi, in agreement with a recent theoretical prediction. Finally, we discuss the accuracy of the method for measuring the surface tension times the cosine of the contact angle of the liquid on the probe. Copyright © 2017 Elsevier Inc. All rights reserved.

Imaging stability in force-feedback high-speed atomic force microscopy

International Nuclear Information System (INIS)

Kim, Byung I.; Boehm, Ryan D.

2013-01-01

We studied the stability of force-feedback high-speed atomic force microscopy (HSAFM) by imaging soft, hard, and biological sample surfaces at various applied forces. The HSAFM images showed sudden topographic variations of streaky fringes with a negative applied force when collected on a soft hydrocarbon film grown on a grating sample, whereas they showed stable topographic features with positive applied forces. The instability of HSAFM images with the negative applied force was explained by the transition between contact and noncontact regimes in the force–distance curve. When the grating surface was cleaned, and thus hydrophilic by removing the hydrocarbon film, enhanced imaging stability was observed at both positive and negative applied forces. The higher adhesive interaction between the tip and the surface explains the improved imaging stability. The effects of imaging rate on the imaging stability were tested on an even softer adhesive Escherichia coli biofilm deposited onto the grating structure. The biofilm and planktonic cell structures in HSAFM images were reproducible within the force deviation less than ∼0.5 nN at the imaging rate up to 0.2 s per frame, suggesting that the force-feedback HSAFM was stable for various imaging speeds in imaging softer adhesive biological samples. - Highlights: ► We investigated the imaging stability of force-feedback HSAFM. ► Stable–unstable imaging transitions rely on applied force and sample hydrophilicity. ► The stable–unstable transitions are found to be independent of imaging rate

Investigation of Redistribution of Pile Foundation Forces Under Successive Loading of Its Elements

Science.gov (United States)

Sedin, Vladimir; Bikus, Kateryna; Kovba, Vladislav

2017-12-01

Redistribution of pile foundation forces under successive loading of its elements was investigated under laboratory conditions. A segment of pile foundation model was taken for use in the case study. Load tests on the pile foundation model segment, without joining its elements (pile and plate, which turns into grillage) and based on different combinations of static loadings were conducted. This proved that the loading of a plate causes skin friction on some length of the pile side surface as well as providing additional loading and settlement. Test results have shown that application of successive elements enables the foundation to carry loads up to 13% higher than in the case of a standard pile foundation loading with the same settlement rates.

A high-force controllable MR fluid damper–liquid spring suspension system

International Nuclear Information System (INIS)

Raja, Pramod; Wang, Xiaojie; Gordaninejad, Faramarz

2014-01-01

The goal of the present research is to investigate the feasibility of incorporating a liquid spring in a semi-active suspension system for use in heavy off-road vehicles. A compact compressible magneto-rheological (MR) fluid damper–liquid spring (CMRFD–LS) with high spring rate is designed, developed and tested. Compressible MR fluids with liquid spring and variable damping characteristics are used. These fluids can offer unique functions in reducing the volume/weight of vehicle struts and improving vehicle dynamic stability and safety. The proposed device consists of a cylinder and piston–rod arrangement with an internal annular MR fluid valve. The internal pressures in the chambers on either side of the piston develop the spring force, while the pressure difference across the MR valve produces the damping force, when the fluid flows through the MR valve. Harmonic characterization of the CMRFD–LS is performed and the force–displacement results are presented. A fluid-mechanics based model is also developed to predict the performance of the system at different operating conditions and compared to the experimental results. Good agreement between the experimental results and theoretical predictions has been achieved. (paper)

Optimizing Armed Forces Capabilities for Hybrid Warfare – New Challenge for Slovak Armed Forces

Directory of Open Access Journals (Sweden)

Peter PINDJÁK

2015-09-01

Full Text Available The paper deals with the optimization of military capabilities of the Slovak Armed Forces for conducting operations in a hybrid conflict, which represents one of the possible scenarios of irregular warfare. Whereas in the regular warfare adversaries intend to eliminate the centers of gravity of each other, most often command and control structures, in irregular conflicts, the center of gravity shifts towards the will and cognitive perception of the target population. Hybrid warfare comprises a thoroughly planned combination of conventional military approaches and kinetic operations with subversive, irregular activities, including information and cyber operations. These efforts are often accompanied by intensified activities of intelligence services, special operation forces, and even mercenary and other paramilitary groups. The development of irregular warfare capabilities within the Slovak Armed Forces will require a progressive transformation process that may turn the armed forces into a modern and adaptable element of power, capable of deployment in national and international crisis management operations.

Interaction of cement model systems with superplasticizers investigated by atomic force microscopy, zeta potential, and adsorption measurements.

Science.gov (United States)

Ferrari, Lucia; Kaufmann, Josef; Winnefeld, Frank; Plank, Johann

2010-07-01

Polyelectrolyte-based dispersants are commonly used in a wide range of industrial applications to provide specific workability to colloidal suspensions. Their working mechanism is based on adsorption onto the surfaces of the suspended particles. The adsorbed polymer layer can exercise an electrostatic and/or a steric effect which is responsible for achieving dispersion. This study is focused on the dispersion forces induced by polycarboxylate ether-based superplasticizers (PCEs) commonly used in concrete. They are investigated by atomic force microscopy (AFM) applying standard silicon nitride tips exposed to solutions with different ionic compositions in a wet cell. Adsorption isotherms and zeta potential analysis were performed to characterize polymer displacement in the AFM system on nonreactive model substrates (quartz, mica, calcite, and magnesium oxide) in order to avoid the complexity of cement hydration products. The results show that PCE is strongly adsorbed by positively charged materials. This fact reveals that, being silicon nitride naturally positively charged, in most cases the superplasticizer adsorbs preferably on the silicon nitride tip than on the AFM substrate. However, the force-distance curves displayed repulsive interactions between tip and substrates even when polymer was poorly adsorbed on both. These observations allow us to conclude that the dispersion due to PCE strongly depends on the particle charge. It differs between colloids adsorbing and not adsorbing PCE, and leads to different forces acting between the particles. Copyright 2010 Elsevier Inc. All rights reserved.

The influence of catch trials on the consolidation of motor memory in force field adaptation tasks

Directory of Open Access Journals (Sweden)

Anne eFocke

2013-07-01

Full Text Available In computational neuroscience it is generally accepted that human motor memory contains neural representations of the physics of the musculoskeletal system and the objects in the environment. These representations are called internal models. Force field studies, in which subjects have to adapt to dynamic perturbations induced by a robotic manipulandum, are an established tool to analyze the characteristics of such internal models. The aim of the current study was to investigate whether catch trials during force field learning could influence the consolidation of motor memory in more complex tasks. Thereby, the force field was more than double the force field of previous studies (35 Ns/m. Moreover, the arm of the subjects was not supported. A total of forty-six subjects participated in this study and performed center-out movements at a robotic manipulandum in two different force fields. Two control groups learned force field A on day 1 and were retested in the same force field on day 3 (AA. Two test groups additionally learned an interfering force field B (=-A on day 2 (ABA. The difference between the two test and control groups, respectively, was the absence (0% or presence (19% of catch trials, in which the force field was turned off suddenly. The results showed consolidation of force field A on day 3 for both control groups. Test groups showed no consolidation of force field A (19% catch trials and even poorer performance on day 3 (0% catch trials. In conclusion, it can be stated that catch trials seem to have a positive effect on the performance on day 3 but do not trigger a consolidation process as shown in previous studies that used a lower force field viscosity with supported arm. These findings indicate that the results of previous studies in which less complex tasks were analyzed, cannot be fully transferred to more complex tasks. Moreover, the effects of catch trials in these situations are insufficiently understood and further research

Electrostatic characteristics of nanostructures investigated using electric force microscopy

International Nuclear Information System (INIS)

Qiu, X.H.; Qi, G.C.; Yang, Y.L.; Wang, C.

2008-01-01

Nanosized materials possess many interesting physical and chemical properties that differ significantly from their macroscopic counterparts. Understanding the size- and shape-dependent properties of nanostructures are of great value to rational design of nanomaterials with desired functionality. Electric force microscopy (EFM) and its variations offer unique opportunities to deepen our insights into the electrical characteristics of nanostructures. In this paper, we review recent progress of this versatile technique and its applications in studying the electrical properties of nanosized materials. A variety of important issues in EFM experimentation and theoretical modeling are discussed, with an emphasis on the ongoing efforts to improve the precision in quantitative measurements of charge density and dielectric properties of nanostructures. - Graphical abstract: We review recent progress of electric force microscopy (EFM) and its applications in studying the electrical properties of nanostructures. A variety of important issues in EFM experimentation and theoretical modeling are discussed, with an emphasis on the ongoing efforts to improve the precision in quantitative measurements of charge density and dielectric properties of nanostructures

Estimation of Coriolis Force and Torque Acting on Ares-1

Science.gov (United States)

Mackey, Ryan M.; Kulikov, Igor K.; Smelyanskiy, Vadim; Luchinsky, Dmitry; Orr, Jeb

2011-01-01

A document describes work on the origin of Coriolis force and estimating Coriolis force and torque applied to the Ares-1 vehicle during its ascent, based on an internal ballistics model for a multi-segmented solid rocket booster (SRB).

Hybrid Force and Position Control Strategy of Robonaut Performing Object Transfer Task

Directory of Open Access Journals (Sweden)

Chen Gang

2018-01-01

Full Text Available This paper proposes a coordinated hybrid force/position control strategy of robonaut performing object transfer operation. Firstly, the constraint relationships between robonaut and object are presented. Base on them, the unified dynamic model of the robonaut and object is established to design the hybrid force/position control method. The movement, the internal force and the external constraint force of the object are considered as the control targets of the control system. Finally, a MATLAB simulation of the robonaut performing object transfer task verifies the correctness and effectiveness of the proposed method. The results show that all the targets can be control accurately by using the method proposed in this paper. The presented control method can control both internal and external forces while maintaining control accuracy, which is a common control strategy.

Inhibition of TRAIL-induced apoptosis and forced internalization of TRAIL receptor 1 by adenovirus proteins.

Science.gov (United States)

Tollefson, A E; Toth, K; Doronin, K; Kuppuswamy, M; Doronina, O A; Lichtenstein, D L; Hermiston, T W; Smith, C A; Wold, W S

2001-10-01

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis through two receptors, TRAIL-R1 (also known as death receptor 4) and TRAIL-R2 (also known as death receptor 5), that are members of the TNF receptor superfamily of death domain-containing receptors. We show that human adenovirus type 5 encodes three proteins, named RID (previously named E3-10.4K/14.5K), E3-14.7K, and E1B-19K, that independently inhibit TRAIL-induced apoptosis of infected human cells. This conclusion was derived from studies using wild-type adenovirus, adenovirus replication-competent mutants that lack one or more of the RID, E3-14.7K, and E1B-19K genes, and adenovirus E1-minus replication-defective vectors that express all E3 genes, RID plus E3-14.7K only, RID only, or E3-14.7K only. RID inhibits TRAIL-induced apoptosis when cells are sensitized to TRAIL either by adenovirus infection or treatment with cycloheximide. RID induces the internalization of TRAIL-R1 from the cell surface, as shown by flow cytometry and indirect immunofluorescence for TRAIL-R1. TRAIL-R1 was internalized in distinct vesicles which are very likely to be endosomes and lysosomes. TRAIL-R1 is degraded, as indicated by the disappearance of the TRAIL-R1 immunofluorescence signal. Degradation was inhibited by bafilomycin A1, a drug that prevents acidification of vesicles and the sorting of receptors from late endosomes to lysosomes, implying that degradation occurs in lysosomes. RID was also shown previously to internalize and degrade another death domain receptor, Fas, and to prevent apoptosis through Fas and the TNF receptor. RID was shown previously to force the internalization and degradation of the epidermal growth factor receptor. E1B-19K was shown previously to block apoptosis through Fas, and both E1B-19K and E3-14.7K were found to prevent apoptosis through the TNF receptor. These findings suggest that the receptors for TRAIL, Fas ligand, and TNF play a role in limiting virus

Atomic force and optical near-field microscopic investigations of polarization holographic gratings in a liquid crystalline azobenzene side-chain polyester

DEFF Research Database (Denmark)

Ramanujam, P.S.; Holme, N.C.R.; Hvilsted, S.

1996-01-01

Atomic force and scanning near-field optical microscopic investigations have been carried out on a polarization holographic grating recorded in an azobenzene side-chain Liquid crystalline polyester. It has been found that immediately following laser irradiation, a topographic surface grating...

Performance investigation on a 4-bed adsorption desalination cycle with internal heat recovery scheme

KAUST Repository

Thu, Kyaw; Yanagi, Hideharu; Saha, Bidyut Baran; Ng, Kim Choon

2016-01-01

Multi-bed adsorption cycle with the internal heat recovery between the condenser and the evaporator is investigated for desalination application. A numerical model is developed for a 4-bed adsorption cycle implemented with the master

Method for lateral force calibration in atomic force microscope using MEMS microforce sensor.

Science.gov (United States)

Dziekoński, Cezary; Dera, Wojciech; Jarząbek, Dariusz M

2017-11-01

In this paper we present a simple and direct method for the lateral force calibration constant determination. Our procedure does not require any knowledge about material or geometrical parameters of an investigated cantilever. We apply a commercially available microforce sensor with advanced electronics for direct measurement of the friction force applied by the cantilever's tip to a flat surface of the microforce sensor measuring beam. Due to the third law of dynamics, the friction force of the equal value tilts the AFM cantilever. Therefore, torsional (lateral force) signal is compared with the signal from the microforce sensor and the lateral force calibration constant is determined. The method is easy to perform and could be widely used for the lateral force calibration constant determination in many types of atomic force microscopes. Copyright © 2017 Elsevier B.V. All rights reserved.

Enforcing international obligations through the use of force?

Czech Academy of Sciences Publication Activity Database

Šturma, Pavel

2008-01-01

Roč. 61, č. 2008 (2008), s. 595-631 ISSN 0035-3256 Institutional research plan: CEZ:AV0Z70680506 Keywords : public international law * weapons of mass destruction * fight against terrorism Subject RIV: AG - Legal Sciences

Mathematics of flexible risers including pressure and internal flow affects

Energy Technology Data Exchange (ETDEWEB)

Seyed, F.B. (John Brown Engineers and Constructors Ltd., London (GB)); Patel, M.H. (University Coll., London (GB). Dept. of Mechanical Engineering)

1992-01-01

Derivations are presented for calculation of pressure and internal flow induced forces on flexible risers and other curved pipes using a mathematically rigorous approach. Approximate and exact methods are presented for calculation of pressure forces on straight and curved pipes in two dimensions. The mathematical identity of these equations with those for effective tension is illustrated. The force arising from the flow of an internal fluid of constant density is then calculated and combined with those for pressure forces in derivation of the catenary equations including pressure and internal flow terms. It is shown that internal flow contributes a new term to the expression for effective tension. These governing equations are then reduced for the specific cases of simple catenary, steep-S, lazy-S, steep-wave and lazy-wave risers. In each case, the solution method has been presented and the governing equilibrium and geometric compatability conditions cited. (author).

Collective coordinates and an accompanying metric force in structural isomerization dynamics of molecules

International Nuclear Information System (INIS)

Yanao, Tomohiro; Takatsuka, Kazuo

2003-01-01

Structural isomerization dynamics of three- and four-atom clusters of vanishing total angular momentum is studied in terms of internal coordinates of n-body systems on the basis of a gauge theory. The so-called principal-axis hyperspherical coordinates are employed effectively as collective variables for the study of isomerization reactions. It turns out that the non-Euclidean metric on the internal space gives rise to a force, which works in response to internal motions called the democratic (kinematic) rotations in the internal space. This metric force generally tends to induce an asymmetry in mass balance of a system, and is coupled with the usual potential force to give rise to trapped motions in the vicinity of the transition states of the cluster. This observation provides a different perspective for the so-called recrossing problem in chemical reaction dynamics

Nonequilibrium forces between neutral atoms mediated by a quantum field

International Nuclear Information System (INIS)

Behunin, Ryan O.; Hu, Bei-Lok

2010-01-01

We study forces between two neutral atoms, modeled as three-dimensional harmonic oscillators, arising from mutual influences mediated by an electromagnetic field but not from their direct interactions. We allow as dynamical variables the center-of-mass motion of the atom, its internal degrees of freedom, and the quantum field treated relativistically. We adopt the method of nonequilibrium quantum field theory which can provide a first-principles, systematic, and unified description including the intrinsic and induced dipole fluctuations. The inclusion of self-consistent back-actions makes possible a fully dynamical description of these forces valid for general atom motion. In thermal equilibrium we recover the known forces--London, van der Waals, and Casimir-Polder--between neutral atoms in the long-time limit. We also reproduce a recently reported force between atoms when the system is out of thermal equilibrium at late times. More noteworthy is the discovery of the existence of a type of (or identification of the source of some known) interatomic force which we call the ''entanglement force,'' originating from the quantum correlations of the internal degrees of freedom of entangled atoms.

Low frequency temperature forcing of chemical oscillations.

Science.gov (United States)

Novak, Jan; Thompson, Barnaby W; Wilson, Mark C T; Taylor, Annette F; Britton, Melanie M

2011-07-14

The low frequency forcing of chemical oscillations by temperature is investigated experimentally in the Belousov-Zhabotinsky (BZ) reaction and in simulations of the Oregonator model with Arrhenius temperature dependence of the rate constants. Forcing with temperature leads to modulation of the chemical frequency. The number of response cycles per forcing cycle is given by the ratio of the natural frequency to the forcing frequency and phase locking is only observed in simulations when this ratio is a whole number and the forcing amplitude is small. The global temperature forcing of flow-distributed oscillations in a tubular reactor is also investigated and synchronisation is observed in the variation of band position with the external signal, reflecting the periodic modulation of chemical oscillations by temperature.

Drag force and jet propulsion investigation of a swimming squid

Directory of Open Access Journals (Sweden)

Tabatabaei Mahdi

2015-01-01

Full Text Available In this study, CAD model of a squid was obtained by taking computer tomography images of a real squid. The model later placed into a computational domain to calculate drag force and performance of jet propulsion. The drag study was performed on the CAD model so that drag force subjected to real squid was revealed at squid’s different swimming speeds and comparison has been made with other underwater creatures (e.g., a dolphin, sea lion and penguin. The drag coefficient (referenced to total wetted surface area of squid is 0.0042 at Reynolds number 1.6x106 that is a %4.5 difference from Gentoo penguin. Besides, jet flow of squid was simulated to observe the flow region generated in the 2D domain utilizing dynamic mesh method to mimic the movement of squid’s mantle cavity.

Investigation of Plasma Spray Coatings as an Alternative to Hard Chrome Plating on Internal Surfaces

National Research Council Canada - National Science Library

Legg, Keith O; Sartwell, Bruce D; Legoux, Jean-Gabriel; Nestler, Montia; Dambra, Christopher; Wang, Daming; Quets, John; Natishan, Paul; Bretz, Philip; Devereaux, Jon

2006-01-01

.... This document constitutes the final report on an investigation of deposition of coatings using miniature plasma spray guns that could replace hard chromium on internal surfaces where conventional...

Nanoscale investigation on Pseudomonas aeruginosa biofilm formed on porous silicon using atomic force microscopy.

Science.gov (United States)

Kannan, Ashwin; Karumanchi, Subbalakshmi Latha; Krishna, Vinatha; Thiruvengadam, Kothai; Ramalingam, Subramaniam; Gautam, Pennathur

2014-01-01

Colonization of surfaces by bacterial cells results in the formation of biofilms. There is a need to study the factors that are important for formation of biofilms since biofilms have been implicated in the failure of semiconductor devices and implants. In the present study, the adhesion force of biofilms (formed by Pseudomonas aeruginosa) on porous silicon substrates of varying surface roughness was quantified using atomic force microscopy (AFM). The experiments were carried out to quantify the effect of surface roughness on the adhesion force of biofilm. The results show that the adhesion force increased from 1.5 ± 0.5 to 13.2 ± 0.9 nN with increase in the surface roughness of silicon substrate. The results suggest that the adhesion force of biofilm is affected by surface roughness of substrate. © 2014 Wiley Periodicals, Inc.

An Investigation of the Posterior Component of Occlusal Force

Science.gov (United States)

1994-05-01

into factors which can contribute to and/or modify bite force. Corrucini et al (1985) reported differences between mouth breathers (diagnosed on history ...both of those factors to be associated with facial morphology. Ingervall et al diagnosed mouth breathing based upon history , rhinomanometrically...that, in normal physiologic function, the dentition is loaded from many directions in addition to purely from an axial direction. Paranormal habits and

Global limit load solutions for thick-walled cylinders with circumferential cracks under combined internal pressure, axial force and bending moment − Part II: Finite element validation

International Nuclear Information System (INIS)

Li, Yuebing; Lei, Yuebao; Gao, Zengliang

2014-01-01

Global limit load solutions for thick-walled cylinders with circumferential internal/external surface and through-wall defects under combined positive/negative axial force, positive/negative global bending moment and internal pressure have been developed in Part I of this paper. In this Part II, elastic-perfectly plastic 3-D finite element (FE) analyses are performed for selected cases, covering a wide range of geometries and load combinations, to validate the developed limit load solutions. The results show that these limit load solutions can predict the FE data very well for the cases with shallow or deep and short cracks and are conservative. For the cases with very long and deep cracks, the predictions are reasonably accurate and more conservative. -- Highlights: • Elastic-perfectly plastic 3D finite element limiting analyses of cylinders. • Thin/thick-walled cylinders with circumferential surface defects. • Combined loading for pressure, end-force and global bending moment. • Totally 1458 cases analysed and tabulated normalised results provided. • Results used to validate the developed limit load solutions in Part I of this paper

Regional Civil Support Forces for Homeland Defense and Civil Support Missions

National Research Council Canada - National Science Library

Nuismer, Barbara A

2007-01-01

To protect the homeland, a plan to form ten regional Civil Support Forces (CSF) made up of National Guard forces has been proposed by senior fellow Christine Wormuth of the Center for Strategic and International Studies (CSIS...

Geologic investigation :an update of subsurface geology on Kirtland Air Force Base, New Mexico.

Energy Technology Data Exchange (ETDEWEB)

Van Hart, Dirk (GRAM, Inc.)

2003-06-01

The objective of this investigation was to generate a revised geologic model of Kirtland Air Force Base (KAFB) incorporating the geological and geophysical data produced since the Site-Wide Hydrogeologic Characterization Project (SWHC) of 1994 and 1995. Although this report has certain stand-alone characteristics, it is intended to complement the previous work and to serve as a status report as of late 2002. In the eastern portion of KAFB (Lurance Canyon and the Hubbell bench), of primary interest is the elevation to which bedrock is buried under a thin cap of alluvium. Elevation maps of the bedrock top reveal the paleodrainage that allows for the interpretation of the area's erosional history. The western portion of KAFB consists of the eastern part of the Albuquerque basin where bedrock is deeply buried under Santa Fe Group alluvium. In this area, the configuration of the down-to-the-west, basin-bounding Sandia and West Sandia faults is of primary interest. New geological and geophysical data and the reinterpretation of old data help to redefine the location and magnitude of these elements. Additional interests in this area are the internal stratigraphy and structure of the Santa Fe Group. Recent data collected from new monitoring wells in the area have led to a geologic characterization of the perched Tijeras Arroyo Groundwater system and have refined the known limits of the Ancestral Rio Grande fluvial sediments within the Santa Fe Group. Both the reinterpretation of the existing data and a review of the regional geology have shown that a segment of the boundary between the eastern and western portions of KAFB is a complicated early Tertiary (Laramide) wrench-fault system, the Tijeras/Explosive Ordnance Disposal Area/Hubbell Spring system. A portion of this fault zone is occupied by a coeval ''pull-apart'' basin filled with early Tertiary conglomerates, whose exposures form the ''Travertine Hills''.

Research Status and Feasibility Analysis on the Participation in International Joint Studies for Radionuclide and Colloid Migration Using Foreign Underground Research Facilities

Energy Technology Data Exchange (ETDEWEB)

Baik, Min Hoon; Park, Chung Kyun; Lee, Jae Kwang; Choi, Jong Won

2007-12-15

The research status of the potential international joint projects that we can join were analyzed by investigating world-wide underground research facilities. Based upon the investigations, we visited Aspo in Sweden and GTS in Switzerland, discussed about the participation in the international joint projects and mutual cooperation, and then discussed in detail about time and method for the participation by inviting an expert from Nagra. It is resulted from the investigations and discussions that it is most relevant to participate in the following two international joint projects. 1) Task Force on Modelling of Groundwater Flow and Transport of Solutes in Aspo, 2) CFM project in GTS. We also summarized the on-going current status for the participation in the two international joint projects.

Women in International Policing: Replacing an “Old Boys Club”?

Directory of Open Access Journals (Sweden)

Saskia Hufnagel

2018-03-01

Full Text Available Globalisation has increased the importance of international police cooperation. While cross-border law enforcement can be traced back as far as the Nineteenth Century, police cooperation today—such as Joint Investigation Teams, International Liaison Officers, and Interpol—only came about in the Twentieth Century. It was developed to counter transnational organised crime, such as drug crime and immigration crime, as well as terrorism. But, another aspect of international policing is that of peacekeeping; that is, the deployment of national police to countries during or after conflict to maintain law and order where the local police do not have sufficient capacities. This paper examines how women have been elevated in this police cooperation role, particularly Interpol and international peacekeeping. The discussion focuses on whether there are indications that internationally related tasks and agencies provide a more accepting environment for female police officers as opposed to a national police force setting.

Experimental and theoretical investigation on the depressurization of a vessel with internals

International Nuclear Information System (INIS)

Vigni, P.; Oriolo, F.; Rosa, U.

1978-01-01

This paper is about some blow-down experiments performed at the Scalbatraio Center of the University of Pisa. The blow-down tests have been made to investigate the depressurization of a vessel with internal structures, reproducing the geometry of a BWR. The experimental data have been compared with calculations performed by the RELAP program, in order to evaluate the scaling effects related to their application to large scale units. (author)

Experimental Investigation of Piston Rings for Internal Combustion Engines

DEFF Research Database (Denmark)

Christiansen, Jens; Klit, Peder; Vølund, Anders

2007-01-01

One of the major prerequisites for calculating piston ring friction is a good description of the tribological situation. A very important condition for describing the frictional behavior of a piston ring correctly is knowledge about the amount of lubricant present. For piston rings the external...... forces are small compared to the rest of the acting forces the main design idea is to fix the piston, while the cylinder liner moves. This approach makes it simple to measure the parameters mentioned above by putting the instrumentation in the piston. The aim of this paper is describe the tribological...

Investigation of Unbalanced Magnetic Force in Magnetic Geared Machine Using Analytical Methods

DEFF Research Database (Denmark)

Zhang, Xiaoxu; Liu, Xiao; Chen, Zhe

2016-01-01

The electromagnetic structure of the magnetic geared machine (MGM) may induce a significant unbalanced magnetic force (UMF). However, few methods have been developed to theoretically reveal the essential reasons for this issue in the MGM. In this paper, an analytical method based on an air....... Second, the magnetic field distribution in the MGM is modeled by an exact subdomain method, which allows the magnetic forces to be calculated quantitatively. The magnetic forces in two MGMs are then studied under no-load and full-load conditions. Finally, the finite-element calculation confirms......-gap relative permeance theory is first developed to qualitatively study the origins of the UMF in the MGM. By means of formula derivations, three kinds of magnetic field behaviors in the air gaps are found to be the potential sources of UMF. It is also proved that the UMF is possible to avoid by design choices...

International building code for bamboo

NARCIS (Netherlands)

Janssen, J.J.A.; Kumar, Arun; Ramanuja Rao, I.V.; Sastry, Cherla

2002-01-01

One of the recommendations in the International Bamboo Congress and Workshop, held at Bali in 1995, requested the International Network for Bamboo and Rattan (INBAR), "to organize a task force to discuss and finalize a building code for bamboo". Consequently a draft was prepared under the title, "An

Black Carbon Radiative Forcing over the Tibetan Plateau

Energy Technology Data Exchange (ETDEWEB)

He, Cenlin; Li, Qinbin; Liou, K. N.; Takano, Y.; Gu, Yu; Qi, L.; Mao, Yuhao; Leung, Lai-Yung R.

2014-11-28

We estimate the snow albedo forcing and direct radiative forcing (DRF) of black carbon (BC) in the Tibetan Plateau using a global chemical transport model in conjunction with a stochastic snow model and a radiative transfer model. Our best estimate of the annual BC snow albedo forcing in the Plateau is 2.9 W m-2 (uncertainty: 1.5–5.0 W m-226 ). We find that BC-snow internal mixing increases the albedo forcing by 40-60% compared with external mixing and coated BC increases the forcing by 30-50% compared with uncoated BC, whereas Koch snowflakes reduce the forcing by 20-40% relative to spherical snow grains. Our best estimate of the annual BC DRF at the top of the atmosphere is 2.3 W m-2 (uncertainty: 0.7–4.3 W m-230 ) in the Plateau after scaling the modeled BC absorption optical depth to Aerosol Robotic Network (AERONET) observations. The BC forcings are attributed to emissions from different regions.

Labour Force Participation Rates of Older Persons: An International Comparison.

Science.gov (United States)

Clark, Robert L.; Anker, Richard

1990-01-01

Using data from 151 countries, labor force participation of older men and women was analyzed and related to economic, demographic, and policy variables. Reduced participation rates are related to increased income levels, structural changes, social security programs, and, for men, the ratio of older persons to persons of standard working age. (SK)

Discrete Lattice effect of various forcing methods of body force on immersed Boundary-Lattice Boltzmann method

Energy Technology Data Exchange (ETDEWEB)

Son, Sung Wan; Ha, Man Yeong; Yoon, Hyun Sik [Pusan National University, Busan (Korea, Republic of); Jeong, Hae Kwon [POSCO, Pohang (Korea, Republic of); Balachandar, S. [University of Florida, Florida (United States)

2013-02-15

We investigate the discrete lattice effect of various forcing methods in the lattice Boltzmann method (LBM) to include the body force obtained from the immersed boundary method (IBM). In the immersed boundary lattice Boltzmann method (IB-LBM), the LBM needs a forcing method to involve the body force on a forcing point near the immersed boundary that is calculated by IBM. The proper forcing method in LBM is derived to include the body force, which appears to resolve problems such as multiphase flow, non-ideal gas behavior, etc. Many researchers have adopted different forcing methods in LBM to involve the body force from IBM, even when they solved similar problems. However, it is necessary to evaluate the discrete lattice effect, which originates from different forcing methods in LBM, to include the effect of the body force from IBM on the results. Consequently, in this study, a rigorous analysis of the discrete lattice effect for different forcing methods in IB-LBM is performed by solving various problems.

Discrete Lattice effect of various forcing methods of body force on immersed Boundary-Lattice Boltzmann method

International Nuclear Information System (INIS)

Son, Sung Wan; Ha, Man Yeong; Yoon, Hyun Sik; Jeong, Hae Kwon; Balachandar, S.

2013-01-01

We investigate the discrete lattice effect of various forcing methods in the lattice Boltzmann method (LBM) to include the body force obtained from the immersed boundary method (IBM). In the immersed boundary lattice Boltzmann method (IB-LBM), the LBM needs a forcing method to involve the body force on a forcing point near the immersed boundary that is calculated by IBM. The proper forcing method in LBM is derived to include the body force, which appears to resolve problems such as multiphase flow, non-ideal gas behavior, etc. Many researchers have adopted different forcing methods in LBM to involve the body force from IBM, even when they solved similar problems. However, it is necessary to evaluate the discrete lattice effect, which originates from different forcing methods in LBM, to include the effect of the body force from IBM on the results. Consequently, in this study, a rigorous analysis of the discrete lattice effect for different forcing methods in IB-LBM is performed by solving various problems.

Molecular force sensors to measure stress in cells

International Nuclear Information System (INIS)

Prabhune, Meenakshi; Rehfeldt, Florian; Schmidt, Christoph F

2017-01-01

Molecularly generated forces are essential for most activities of biological cells, but also for the maintenance of steady state or homeostasis. To quantitatively understand cellular dynamics in migration, division, or mechanically guided differentiation, it will be important to exactly measure stress fields within the cell and the extracellular matrix. Traction force microscopy and related techniques have been established to determine the stress transmitted from adherent cells to their substrates. However, different approaches are needed to directly assess the stress generated inside the cell. This has recently led to the development of novel molecular force sensors. In this topical review, we briefly mention methods used to measure cell-external forces, and then summarize and explain different designs for the measurement of cell-internal forces with their respective advantages and disadvantages. (topical review)

Results of investigations of an 0.010-scale 140A/B configuration (model 72-OTS) of the Rockwell International space shuttle orbiter in the NASA/Langley Research Center unitary plan wind tunnel

Science.gov (United States)

Petrozzi, M. T.; Milam, M. D.

1975-01-01

Experimental aerodynamic investigations were conducted in the NASA/Langley unitary plan wind tunnel on a sting mounted 0.010-scale outer mold line model of the 140A/B configuration of the Rockwell International Space Shuttle Vehicle. The primary test objectives were to obtain: (1) six component force and moment data for the mated vehicle at subsonic and transonic conditions, (2) effects of configuration build-up, (3) effects of protuberances, ET/orbiter fairings and attach structures, and (4) elevon deflection effects on wing bending moment. Six component aerodynamic force and moment data and base and balance cavity pressures were recorded over Mach numbers of 1.6, 2.0, 2.5, 2.86, 3.9, and 4.63 at a nominal Reynolds number of 20 to the 6th power per foot. Selected configurations were tested at angles of attack and sideslip from -10 deg to +10 deg. For all configurations involving the orbiter, wing bending, and torsion coefficients were measured on the right wing.

An experimental investigation on the effects of exponential window and impact force level on harmonic reduction in impact-synchronous model analysis

Energy Technology Data Exchange (ETDEWEB)

Chao, Ong Zhi; Cheet, Lim Hong; Yee, Khoo Shin [Mechanical Engineering Department, Faculty of EngineeringUniversity of Malaya, Kuala Lumpur (Malaysia); Rahman, Abdul Ghaffar Abdul [Faculty of Mechanical Engineering, University Malaysia Pahang, Pekan (Malaysia); Ismail, Zubaidah [Civil Engineering Department, Faculty of Engineering, University of Malaya, Kuala Lumpur (Malaysia)

2016-08-15

A novel method called Impact-synchronous modal analysis (ISMA) was proposed previously which allows modal testing to be performed during operation. This technique focuses on signal processing of the upstream data to provide cleaner Frequency response function (FRF) estimation prior to modal extraction. Two important parameters, i.e., windowing function and impact force level were identified and their effect on the effectiveness of this technique were experimentally investigated. When performing modal testing during running condition, the cyclic loads signals are dominant in the measured response for the entire time history. Exponential window is effectively in minimizing leakage and attenuating signals of non-synchronous running speed, its harmonics and noises to zero at the end of each time record window block. Besides, with the information of the calculated cyclic force, suitable amount of impact force to be applied on the system could be decided prior to performing ISMA. Maximum allowable impact force could be determined from nonlinearity test using coherence function. By applying higher impact forces than the cyclic loads along with an ideal decay rate in ISMA, harmonic reduction is significantly achieved in FRF estimation. Subsequently, the dynamic characteristics of the system are successfully extracted from a cleaner FRF and the results obtained are comparable with Experimental modal analysis (EMA)

An experimental investigation on the effects of exponential window and impact force level on harmonic reduction in impact-synchronous model analysis

International Nuclear Information System (INIS)

Chao, Ong Zhi; Cheet, Lim Hong; Yee, Khoo Shin; Rahman, Abdul Ghaffar Abdul; Ismail, Zubaidah

2016-01-01

A novel method called Impact-synchronous modal analysis (ISMA) was proposed previously which allows modal testing to be performed during operation. This technique focuses on signal processing of the upstream data to provide cleaner Frequency response function (FRF) estimation prior to modal extraction. Two important parameters, i.e., windowing function and impact force level were identified and their effect on the effectiveness of this technique were experimentally investigated. When performing modal testing during running condition, the cyclic loads signals are dominant in the measured response for the entire time history. Exponential window is effectively in minimizing leakage and attenuating signals of non-synchronous running speed, its harmonics and noises to zero at the end of each time record window block. Besides, with the information of the calculated cyclic force, suitable amount of impact force to be applied on the system could be decided prior to performing ISMA. Maximum allowable impact force could be determined from nonlinearity test using coherence function. By applying higher impact forces than the cyclic loads along with an ideal decay rate in ISMA, harmonic reduction is significantly achieved in FRF estimation. Subsequently, the dynamic characteristics of the system are successfully extracted from a cleaner FRF and the results obtained are comparable with Experimental modal analysis (EMA)

Investigating Internalization and Intracellular Trafficking of GPCRs

DEFF Research Database (Denmark)

Foster, Simon R; Bräuner-Osborne, Hans

2017-01-01

for signal transduction. One of the major mechanisms for GPCR regulation involves their endocytic trafficking, which serves to internalize the receptors from the plasma membrane and thereby attenuate G protein-dependent signaling. However, there is accumulating evidence to suggest that GPCRs can signal...... independently of G proteins, as well as from intracellular compartments including endosomes. It is in this context that receptor internalization and intracellular trafficking have attracted renewed interest within the GPCR field. In this chapter, we will review the current understanding and methodologies...

Capillary forces in tapping mode atomic force microscopy

NARCIS (Netherlands)

Zitzler, L.; Herminghaus, S.; Mugele, Friedrich Gunther

2002-01-01

We investigated the influence of the relative humidity on amplitude and phase of the cantilever oscillation while operating an atomic force microscope (AFM) in the tapping mode. If the free oscillation amplitude A0 exceeds a certain critical amplitude Ac, the amplitude- and phase-distance curves

Study and development of indirect force measurement. Application to the identification of diesel engine internal sources; Etude et developpement de la mesure indirecte d'efforts. Application a l'identification des sources internes d'un moteur Diesel

Energy Technology Data Exchange (ETDEWEB)

Leclere, Q.

2003-12-15

The aim of this work is to develop a diagnostic method allowing to quantify vibratory sources of stationary operating machines from measurements. The direct measurement of sources using a force sensor is often difficult to obtain, not to say impossible. Thus, their estimation is assessed from both operating response measurements and a transfer model of the structure. Concerning the method, several original developments are put forward, especially to optimise the technique when the machine structure has an heterogeneous dynamic behaviour. Moreover, a reliability indicator of the force estimation is introduced, based on the comparison between different approaches of the transfer system inversion. The reliability of results are indeed a crucial point for indirect force measurement, because the technique is known to be very sensitive to different types of errors (measurement noise, model error). The method is applied to the identification of Diesel engine internal sources. A special attention is paid to the construction of the transfer model, estimated by both experimental and numerical approaches. Identified forces are compared to excitations computed through a simple drive train model. The comparison allows to underline some model deficiencies as well as the relative robustness of the method. A source ranking operation is realized in order to present the interest of the indirect force measurement results. (author)

Force-Time Entropy of Isometric Impulse.

Science.gov (United States)

Hsieh, Tsung-Yu; Newell, Karl M

2016-01-01

The relation between force and temporal variability in discrete impulse production has been viewed as independent (R. A. Schmidt, H. Zelaznik, B. Hawkins, J. S. Frank, & J. T. Quinn, 1979 ) or dependent on the rate of force (L. G. Carlton & K. M. Newell, 1993 ). Two experiments in an isometric single finger force task investigated the joint force-time entropy with (a) fixed time to peak force and different percentages of force level and (b) fixed percentage of force level and different times to peak force. The results showed that the peak force variability increased either with the increment of force level or through a shorter time to peak force that also reduced timing error variability. The peak force entropy and entropy of time to peak force increased on the respective dimension as the parameter conditions approached either maximum force or a minimum rate of force production. The findings show that force error and timing error are dependent but complementary when considered in the same framework with the joint force-time entropy at a minimum in the middle parameter range of discrete impulse.

Changes in gluteal muscle forces with alteration of footstrike pattern during running.

Science.gov (United States)

Vannatta, Charles Nathan; Kernozek, Thomas W; Gheidi, Naghmeh

2017-10-01

Gait retraining is a common form of treatment for running related injuries. Proximal factors at the hip have been postulated as having a role in the development of running related injuries. How altering footstrike affects hip muscles forces and kinematics has not been described. Thus, we aimed to quantify differences in hip muscle forces and hip kinematics that may occur when healthy runners are instructed to alter their foot strike pattern from their habitual rear-foot strike to a forefoot strike. This may gain insight on the potential etiology and treatment methods of running related lower extremity injury. Twenty-five healthy female runners completed a minimum of 10 running trials in a controlled laboratory setting under rear-foot strike and instructed forefoot strike conditions. Kinetic and kinematic data were used in an inverse dynamic based static optimization to estimate individual muscle forces during running. Within subject differences were investigated using a repeated measures multi-variate analysis of variance. Peak gluteus medius and minimus and hamstring forces were reduced while peak gluteus maximus force was increased when running with an instructed forefoot strike pattern. Peak hip adduction, hip internal rotation, and heel-COM distance were also reduced. Therefore, instructing habitual rearfoot strike runners to run with a forefoot strike pattern resulted in changes in peak gluteal and hamstring muscle forces and hip kinematics. These changes may be beneficial to the development and treatment of running related lower extremity injury. Copyright © 2017 Elsevier B.V. All rights reserved.

Forced response of the East Asian summer rainfall over the past millennium: results from a coupled model simulation

Energy Technology Data Exchange (ETDEWEB)

Liu, Jian; Wang, Hongli; Ti, Ruyuan [Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, State Key Laboratory of Lake Science and Environment, Nanjing (China); Wang, Bin [University of Hawaii at Manoa, Department of Meteorology and IPRC, Honolulu, HI (United States); Kuang, Xueyuan [Nanjing University, School of Atmospheric Sciences, Nanjing (China)

2011-01-15

The centennial-millennial variation of the East Asian summer monsoon (EASM) precipitation over the past 1000 years was investigated through the analysis of a millennium simulation of the coupled ECHO-G model. The model results indicate that the centennial-millennial variation of the EASM is essentially a forced response to the external radiative forcing (insolation, volcanic aerosol, and green house gases). The strength of the response depends on latitude; and the spatial structure of the centennial-millennial variation differs from the interannual variability that arises primarily from the internal feedback processes within the climate system. On millennial time scale, the extratropical and subtropical precipitation was generally strong during Medieval Warm Period (MWP) and weak during Little Ice Age (LIA). The tropical rainfall is insensitive to the effective solar radiation forcing (insolation plus radiative effect of volcanic aerosols) but significantly responds to the modern anthropogenic radiative forcing. On centennial time scale, the variation of the extratropical and subtropical rainfall also tends to follow the effective solar radiation forcing closely. The forced response features in-phase rainfall variability between the extratropics and subtropics, which is in contrast to the anti-correlation on the interannual time scale. Further, the behavior of the interannual-decadal variation in the extratropics is effectively modulated by change of the mean states on the millennial time scale, suggesting that the structure of the internal mode may vary with significant changes in the external forcing. These findings imply that on the millennial time scale, (a) the proxy data in the extratropical EA may more sensitively reflect the EASM rainfall variations, and (b) the Meiyu and the northern China rainfall provide a consistent measure for the EASM strength. (orig.)

Thermal creep force: analysis and application

OpenAIRE

Wolfe, David M.

2016-01-01

Approved for public release; distribution is unlimited The existence of two motive forces on a Crookes radiometer has complicated the investigation of either force independently. The thermal creep shear force, in particular, has been subject to differing interpretations of the direction in which it acts and its order of magnitude. A horizontal vane radiometer design is provided, which isolates the thermal creep shear force. The horizontal vane radiometer is explored through experiment, kin...

The effect of shear force on ink transfer in gravure offset printing

International Nuclear Information System (INIS)

Lee, Taik-Min; Lee, Seung-Hyun; Noh, Jae-Ho; Kim, Dong-Soo; Chun, Sangki

2010-01-01

This paper asserts that shear force plays an important role in the printing mechanism of gravure offset line printing. To that end, a theoretical printing model showing shear force dependence on the printing angle is proposed. The decrement of the internal angle between the printing direction and the pattern-line direction increases shear force, thereby enhancing the amount of transferred ink in the off stage. A printing experiment using pattern-line widths of 80 µm and 20 µm shows the angle dependence of the line width, thickness and amount of transferred ink, reflecting the effect of shear force. The effect of the internal angle on cross-sectional differences in lines with a width of 20 µm and with angle variation is greater than that in lines with a width of 80 µm, which corresponds with the theoretical prediction that shear force has greater influence on a narrower line. The strong correlation between the experimental data and the theoretical model supports the validation of the theoretical model

Climate Implications of the Heterogeneity of Anthropogenic Aerosol Forcing

Science.gov (United States)

Persad, Geeta Gayatri

Short-lived anthropogenic aerosols are concentrated in regions of high human activity, where they interact with radiation and clouds, causing horizontally heterogeneous radiative forcing between polluted and unpolluted regions. Aerosols can absorb shortwave energy in the atmosphere, but deplete it at the surface, producing opposite radiative perturbations between the surface and atmosphere. This thesis investigates climate and policy implications of this horizontal and vertical heterogeneity of anthropogenic aerosol forcing, employing the Geophysical Fluid Dynamics Laboratory's AM2.1 and AM3 models, both at a global scale and using East Asia as a regional case study. The degree of difference between spatial patterns of climate change due to heterogeneous aerosol forcing versus homogeneous greenhouse gas forcing deeply impacts the detection, attribution, and prediction of regional climate change. This dissertation addresses a gap in current understanding of these two forcings' response pattern development, using AM2.1 historical forcing simulations. The results indicate that fast atmospheric and land-surface processes alone substantially homogenize the global pattern of surface energy flux response to heterogeneous aerosol forcing. Aerosols' vertical redistribution of energy significantly impacts regional climate, but is incompletely understood. It is newly identified here, via observations and historical and idealized forcing simulations, that increased aerosol-driven atmospheric absorption may explain half of East Asia's recent surface insolation decline. Further, aerosols' surface and atmospheric effects counteract each other regionally---atmospheric heating enhances summer monsoon circulation, while surface dimming suppresses it---but absorbing aerosols' combined effects reduce summer monsoon rainfall. This thesis constitutes the first vertical decomposition of aerosols' impacts in this high-emissions region and elucidates the monsoonal response to aerosols

Atomic force microscopy investigation of growth process of organic TCNQ aggregates on SiO2 and mica substrates

Science.gov (United States)

Huan, Qing; Hu, Hao; Pan, Li-Da; Xiao, Jiang; Du, Shi-Xuan; Gao, Hong-Jun

2010-08-01

Deposition patterns of tetracyanoquinodimethane (TCNQ) molecules on different surfaces are investigated by atomic force microscopy. A homemade physical vapour deposition system allows the better control of molecule deposition. Taking advantage of this system, we investigate TCNQ thin film growth on both SiO2 and mica surfaces. It is found that dense island patterns form at a high deposition rate, and a unique seahorse-like pattern forms at a low deposition rate. Growth patterns on different substrates suggest that the fractal pattern formation is dominated by molecule-molecule interaction. Finally, a phenomenal “two-branch" model is proposed to simulate the growth process of the seahorse pattern.

Atomic force microscopy investigation of growth process of organic TCNQ aggregates on SiO2 and mica substrates

International Nuclear Information System (INIS)

Qing, Huan; Hao, Hu; Li-Da, Pan; Jiang, Xiao; Shi-Xuan, Du; Hong-Jun, Gao

2010-01-01

Deposition patterns of tetracyanoquinodimethane (TCNQ) molecules on different surfaces are investigated by atomic force microscopy. A homemade physical vapour deposition system allows the better control of molecule deposition. Taking advantage of this system, we investigate TCNQ thin film growth on both SiO 2 and mica surfaces. It is found that dense island patterns form at a high deposition rate, and a unique seahorse-like pattern forms at a low deposition rate. Growth patterns on different substrates suggest that the fractal pattern formation is dominated by molecule–molecule interaction. Finally, a phenomenal “two-branch” model is proposed to simulate the growth process of the seahorse pattern. (general)

A combined optical and atomic force microscope for live cell investigations

International Nuclear Information System (INIS)

Madl, Josef; Rhode, Sebastian; Stangl, Herbert; Stockinger, Hannes; Hinterdorfer, Peter; Schuetz, Gerhard J.; Kada, Gerald

2006-01-01

We present an easy-to-use combination of an atomic force microscope (AFM) and an epi-fluorescence microscope, which allows live cell imaging under physiological conditions. High-resolution AFM images were acquired while simultaneously monitoring either the fluorescence image of labeled membrane components, or a high-contrast optical image (DIC, differential interference contrast). By applying two complementary techniques at the same time, additional information and correlations between structure and function of living organisms were obtained. The synergy effects between fluorescence imaging and AFM were further demonstrated by probing fluorescence-labeled receptor clusters in the cell membrane via force spectroscopy using antibody-functionalized tips. The binding probability on receptor-containing areas identified with fluorescence microscopy ('receptor-positive sites') was significantly higher than that on sites lacking receptors

Investigating the Linear Dependence of Direct and Indirect Radiative Forcing on Emission of Carbonaceous Aerosols in a Global Climate Model

Energy Technology Data Exchange (ETDEWEB)

Chen, Yanju [Department of Civil and Environmental Engineering, University of Illinois at Urbana-Champaign, Urbana IL USA; Wang, Hailong [Atmospheric Sciences and Global Change Division, Pacific Northwest National Laboratory, Richland WA USA; Singh, Balwinder [Atmospheric Sciences and Global Change Division, Pacific Northwest National Laboratory, Richland WA USA; Ma, Po-Lun [Atmospheric Sciences and Global Change Division, Pacific Northwest National Laboratory, Richland WA USA; Rasch, Philip J. [Atmospheric Sciences and Global Change Division, Pacific Northwest National Laboratory, Richland WA USA; Bond, Tami C. [Department of Civil and Environmental Engineering, University of Illinois at Urbana-Champaign, Urbana IL USA

2018-02-02

The linearity of dependence of aerosol direct and indirect radiative forcing (DRF and IRF) on emissions is essential to answer the policy-relevant question on how the change in forcing would result from a change in emission. In this study, the forcing-to-emission relationship is investigated for black carbon (BC) and primary organic carbon (OC) emitted from North America and Asia. Direct and indirect radiative forcing of BC and OC are simulated with the Community Atmosphere Model (CAM5.1). Two diagnostics are introduced to aid in policy-relevant discussion: emission-normalized forcing (ENF) and linearity (R). DRF is linearly related to emission for both BC and OC from the two regions and emission-normalized DRF is similar, within 15%. IRF is linear to emissions for weaker sources and regions far from source (North American BC and OC), while for large emission sources and near source regions (Asian OC) the response of forcing to emission is sub-linear. In North America emission-normalized IRF (ENIRF) is 2-4 times higher than that in Asia. The difference among regions and species is primarily caused by failure of accumulation mode particles to become CCN, and then to activate into CDNC. Optimal aggregation area (30ºx 30º) has been used to communicate the regional variation of forcing-to-emission relationship. For IRF, only 15-40% of the Earth’s surface is significantly affected by the two emission regions, but the forcing in these regions comprises most of the global impact. Linearity of IRF occurs in about two-thirds of the significant regions except for Asian OC. ENF is an effective tool to estimate forcing changes due to reduction of surface emissions, as long as there is sufficient attention to the causes of nonlinearity in the simulations used to derive ENIRF (emission into polluted regions and emission elevation). The differences in ENIRF have important implications for policy decisions. Lower ENIRF in more polluted region like Asia means that reductions of

Surface structure investigations using noncontact atomic force microscopy

International Nuclear Information System (INIS)

Kolodziej, J.J.; Such, B.; Goryl, M.; Krok, F.; Piatkowski, P.; Szymonski, M.

2006-01-01

Surfaces of several A III B V compound semiconductors (InSb, GaAs, InP, InAs) of the (0 0 1) orientation have been studied with noncontact atomic force microscopy (NC-AFM). Obtained atomically resolved patterns have been compared with structural models available in the literature. It is shown that NC-AFM is an efficient tool for imaging complex surface structures in real space. It is also demonstrated that the recent structural models of III-V compound surfaces provide a sound base for interpretation of majority of features present in recorded patterns. However, there are also many new findings revealed by the NC-AFM method that is still new experimental technique in the context of surface structure determination

International Taxation of Philanthropy : Removing tax obstacles for international charities

NARCIS (Netherlands)

Koele, I.A.

2007-01-01

Non-profit organizations are increasingly subjected to the forces of globalization. Although this should not come as a surprise, it is curious to note that the taxation of international philanthropy is an area where discrimination as to residence is still very obvious. Whereas domestic philanthropic

On the use of quartic force fields in variational calculations

Science.gov (United States)

Fortenberry, Ryan C.; Huang, Xinchuan; Yachmenev, Andrey; Thiel, Walter; Lee, Timothy J.

2013-06-01

Quartic force fields (QFFs) have been shown to be one of the most effective ways to efficiently compute vibrational frequencies for small molecules. In this letter we discuss how the simple-internal or bond-length bond-angle (BLBA) coordinates can be transformed into Morse-cosine (-sine) coordinates which produce potential energy surfaces from QFFs that possess proper limiting behavior and can describe the vibrational (or rovibrational) energy levels of an arbitrary molecular system to 5 cm-1 or better compared to experiment. We investigate parameter scaling in the Morse coordinate, symmetry considerations, and examples of transformed QFFs making use of the MULTIMODE, TROVE, and VTET variational vibrational methods.

An investigation of major influences on the seismic response of APR1400 reactor vessel internals - 15145

International Nuclear Information System (INIS)

Byun, Y.J.; Kim, J.G.; Sung, K.K.; Lee, D.H.

2015-01-01

This paper deals with 3 topics concerning the APR1400 reactor vessel internals (RVI) seismic analysis: nonlinear problems, approaches to account for uncertainties of seismic model, and dynamic responses to various seismic excitations. First, the noticeable nonlinear characteristics of the RVI seismic model are discussed, and the modeling methods for properly simulating the nonlinear behaviors of RVI under seismic loads are presented. By applying these methods to the seismic model, the seismic analysis can correctly predict the dynamic response of RVI. Next, two approaches to account for the uncertainties of seismic model are evaluated: the time history broadening method, and the sensitivity analysis based on NUREG-0800, Section 4.2, Appendix A. From the evaluation results, it is confirmed that the time history broadening method employed in the seismic analysis of APR1400 RVI sufficiently accounts for the uncertainty of seismic model. Finally, the response characteristics of APR1400 RVI to various seismic excitations are investigated. The seismic excitations corresponding to various soil profiles, including the effects of cracked and un-cracked concrete stiffness on the reactor containment building structure, are used as forcing functions. From this study, the effects of various site conditions on the dynamic response of APR1400 RVI are identified. As a result, the enveloped seismic responses obtained from this study will contribute to the development of RVI seismic design that covers a wide range of potential site conditions. (authors)

New advances in the forced response computation of periodic structures using the wave finite element (WFE) method

OpenAIRE

Mencik , Jean-Mathieu

2014-01-01

International audience; The wave finite element (WFE) method is investigated to describe the harmonic forced response of onedimensional periodic structures like those composed of complex substructures and encountered in engineering applications. The dynamic behavior of these periodic structures is analyzed over wide frequency bands where complex spatial dynamics, inside the substructures, are likely to occur.Within theWFE framework, the dynamic behavior of periodic structures is described in ...

Investigation of pile foundations of nuclear power plants with help of non linear analyses

International Nuclear Information System (INIS)

Diaz, B.E.; Schulz, M.; Costa, E.; Vaz, L.E.

1984-01-01

A few important 1300 MW PWR nuclear power plants have been built over pile foundations. The design requirements of Nuclear Power Plants prescribe accurate investigation of the as built conditions of the foundation. This study must take into account the actual concrete strength existent among and along the pile shafts of the foundation. In order to simulate the structural response of the foundation up to the failure, a non linear analysis must be performed. In this paper the required computer analysis procedures will be described. It can be verified that the redistribution of the internal forces in this highly hyperstatic soil-structure system can be of two types. The total applied forces over the foundation are redistributed among the piles and for each pile itself a local redistribution of forces takes place along the pile shaft. This type of analysis allows an accurate investigation of the actual safety margin existent in the pile foundation, based on the actual as built conditions of the construction. (Author) [pt

Investigating the effective factors on management internal controls applying

Directory of Open Access Journals (Sweden)

Ahmad Ahmadkhani

2012-08-01

Full Text Available Information technology plays an important role on increasing internal control in many organizations. In this paper, we present an empirical study to measure the impact of information technology, hiring high quality skilled management team, using high quality standards and increasing employees' awareness on managing internal control. The survey uses a questionnaire based on Likert scale and distributes among the people who work in either administration or financial sectors of governmental agencies in province of Zanjan, Iran. The results of the study indicate that the implementation of information technology positively influences management team to control their system, more effectively, using more skilled and specialized managers positively influences management internal control, an organization with suitable standard positively influences management internal control and increasing employees' awareness positively influences management internal control.

Surface electromyography activity of the rectus abdominis, internal oblique, and external oblique muscles during forced expiration in healthy adults.

Science.gov (United States)

Ito, Kenichi; Nonaka, Koji; Ogaya, Shinya; Ogi, Atsushi; Matsunaka, Chiaki; Horie, Jun

2016-06-01

We aimed to characterize rectus abdominis, internal oblique, and external oblique muscle activity in healthy adults under expiratory resistance using surface electromyography. We randomly assigned 42 healthy adult subjects to 3 groups: 30%, 20%, and 10% maximal expiratory intraoral pressure (PEmax). After measuring 100% PEmax and muscle activity during 100% PEmax, the activity and maximum voluntary contraction of each muscle during the assigned experimental condition were measured. At 100% PEmax, the external oblique (pinternal oblique (pexternal oblique (pinternal oblique (pexternal oblique: pinternal oblique: p<0.01). The abdominal oblique muscles are the most active during forced expiration. Moreover, 30% PEmax is the minimum intensity required to achieve significant, albeit very slight, muscle activity during expiratory resistance. Copyright © 2016 Elsevier Ltd. All rights reserved.

Mechanical design and force calibration of dual-axis micromechanical probe for friction force microscopy

International Nuclear Information System (INIS)

Fukuzawa, Kenji; Terada, Satoshi; Shikida, Mitsuhiro; Amakawa, Hiroaki; Zhang, Hedong; Mitsuya, Yasunaga

2007-01-01

A dual-axis micromechanical probe that combines a double cantilever and torsion beams is presented. This probe can reduce the mechanical cross-talk between the lateral and vertical force detections. In addition, dual-axis forces can be detected by measuring the dual-axis displacement of the probe end using the optical lever-based method used in conventional friction force microscopes (FFMs). In this paper, the mechanical design of the probe, the details of the fabrication method, FFM performance, and calibration of the friction force are discussed. The mechanical design and the microfabrication method for probes that can provide a force resolution of the order of 1 nN without mechanical cross-talk are presented. Calibration of the lateral force signal is possible by using the relationship between the lateral force and the piezodisplacement at the onset of the probe scanning. The micromechanical probe enables simultaneous and independent detection of atomic and friction forces. This leads to accurate investigation of nanotribological phenomena and visualization of the distribution of the friction properties, which helps the identification of the material properties

Reorganised force control in elbow pain patients during isometric wrist extension

DEFF Research Database (Denmark)

Mista, Christian Ariel; Monterde, Sonia; Inglés, Montserrat

2018-01-01

INTRODUCTION: Reorganised force control may be an important adaptation following painful traumas. In this study, force control adaptations were assessed in elbow pain patients. Increasing the contraction demand may overcome pain interference on the motor control and as such act as an internal...... voluntary contraction. Pressure pain thresholds were recorded at the lateral epicondyle and tibialis anterior muscle. Contraction force was recorded using a three-directional force transducer. Participants performed contractions according with visual feedback of the task-related force intensity (main...... direction of wrist extension) and another set of contractions with feedback of the three force directions. Going from the simple to the detailed force feedback will increase the demand of the motor task. Force steadiness in all 3 dimensions and force direction was extracted. RESULTS: Compared with controls...

A combined optical and atomic force microscope for live cell investigations

Energy Technology Data Exchange (ETDEWEB)

Madl, Josef [Institute for Biophysics, Johannes Kepler University Linz, Altenbergerstr. 69, 4040 Linz (Austria); Rhode, Sebastian [Institute for Biophysics, Johannes Kepler University Linz, Altenbergerstr. 69, 4040 Linz (Austria); Stangl, Herbert [Institute for Medical Chemistry, Medical University Vienna, Waehringerstr. 10, 1090 Vienna (Austria); Stockinger, Hannes [Department of Molecular Immunology, Center for Biomolecular Medicine and Pharmacology, Medical University Vienna, Lazarettgasse 19, 1090 Vienna (Austria); Hinterdorfer, Peter [Institute for Biophysics, Johannes Kepler University Linz, Altenbergerstr. 69, 4040 Linz (Austria); Schuetz, Gerhard J. [Institute for Biophysics, Johannes Kepler University Linz, Altenbergerstr. 69, 4040 Linz (Austria); Kada, Gerald [Scientec, Mitterbauerweg 4, 4020 Linz (Austria)]. E-mail: gerald_kada@agilent.com

2006-06-15

We present an easy-to-use combination of an atomic force microscope (AFM) and an epi-fluorescence microscope, which allows live cell imaging under physiological conditions. High-resolution AFM images were acquired while simultaneously monitoring either the fluorescence image of labeled membrane components, or a high-contrast optical image (DIC, differential interference contrast). By applying two complementary techniques at the same time, additional information and correlations between structure and function of living organisms were obtained. The synergy effects between fluorescence imaging and AFM were further demonstrated by probing fluorescence-labeled receptor clusters in the cell membrane via force spectroscopy using antibody-functionalized tips. The binding probability on receptor-containing areas identified with fluorescence microscopy ('receptor-positive sites') was significantly higher than that on sites lacking receptors.

Deficits of anticipatory grip force control after damage to peripheral and central sensorimotor systems.

Science.gov (United States)

Hermsdörfer, Joachim; Hagl, Elke; Nowak, Dennis A

2004-11-01

Healthy subjects adjust their grip force economically to the weight of a hand-held object. In addition, inertial loads, which arise from arm movements with the grasped object, are anticipated by parallel grip force modulations. Internal forward models have been proposed to predict the consequences of voluntary movements. Anesthesia of the fingers impairs grip force economy but the feedforward character of the grip force/load coupling is preserved. To further analyze the role of sensory input for internal forward models and to characterize the consequences of central nervous system damage for anticipatory grip force control, we measured grip force behavior in neurological patients. We tested a group of stroke patients with varying degrees of impaired fine motor control and sensory loss, a single patient with complete and permanent differentation from all tactile and proprioceptive input, and a group of patients with amyotrophic lateral sclerosis (ALS) that exclusively impairs the motor system without affecting sensory modalities. Increased grip forces were a common finding in all patients. Sensory deficits were a strong but not the only predictor of impaired grip force economy. The feedforward mode of grip force control was typically preserved in the stroke patients despite their central sensory deficits, but was severely disturbed in the patient with peripheral sensory deafferentation and in a minority of stroke patients. Moderate deficits of feedforward control were also obvious in ALS patients. Thus, the function of the internal forward model and the precision of grip force production may depend on a complex anatomical and functional network of sensory and motor structures and their interaction in time and space.

Expanding the role of internal facility assessments

Energy Technology Data Exchange (ETDEWEB)

Kolpa, R.L.; Levenson, J.B. [Argonne National Lab., IL (United States); Weaver, M.A. [Headquarters Air Force Materiel Command, Wright-Patterson AFB, OH (United States)

1996-05-01

The US Air Force (USAF) Environmental Compliance Assessment and Management Program (ECAMP) is an effective and comprehensive system to evaluate environmental compliance at individual USAF installations. The ECAMP assessment is typically performed by a team of experts from the installation`s Major Command (MAJCOM) Headquarters, and is often augmented with technical contractor support. As directed by Air Force policy, an external ECAMP assessment is required at a minimum of every three years for each installation. In the intervening years, each installation is required to perform an internal ECAMP assessment, with its own personnel and resources. Even though team composition differs, the internal and external ECAMP assessments are likely to be very similar in scope, objectives, and deliverables. For over nine years, Argonne National Laboratory (ANL) has supported several Air Force MAJCOMs in performing their external ECAMP assessments. More recently, ANL has also had the opportunity to provide technical support and training at individual installations during their preparation and conduct of internal ECAMP assessments. From that experience, the authors have learned that the quality and value of the internal assessment is enhanced by making it a vehicle for training, planning, and interaction among organizations. Various strategies and techniques have been successfully employed to derive maximum benefit and insight from the internal assessment process. Experiences that involve expanding the scope and objectives of internal assessments to meet specific goals are presented. The expansion of scope and objectives include preassessment training, planning, and evaluator interactions as part of the overall internal assessment process.

Force sharing and other collaborative strategies in a dyadic force perception task.

Science.gov (United States)

Tatti, Fabio; Baud-Bovy, Gabriel

2018-01-01

When several persons perform a physical task jointly, such as transporting an object together, the interaction force that each person experiences is the sum of the forces applied by all other persons on the same object. Therefore, there is a fundamental ambiguity about the origin of the force that each person experiences. This study investigated the ability of a dyad (two persons) to identify the direction of a small force produced by a haptic device and applied to a jointly held object. In this particular task, the dyad might split the force produced by the haptic device (the external force) in an infinite number of ways, depending on how the two partners interacted physically. A major objective of this study was to understand how the two partners coordinated their action to perceive the direction of the third force that was applied to the jointly held object. This study included a condition where each participant responded independently and another one where the two participants had to agree upon a single negotiated response. The results showed a broad range of behaviors. In general, the external force was not split in a way that would maximize the joint performance. In fact, the external force was often split very unequally, leaving one person without information about the external force. However, the performance was better than expected in this case, which led to the discovery of an unanticipated strategy whereby the person who took all the force transmitted this information to the partner by moving the jointly held object. When the dyad could negotiate the response, we found that the participant with less force information tended to switch his or her response more often.

Realising traceable electrostatic forces despite non-linear balance motion

International Nuclear Information System (INIS)

Stirling, Julian; Shaw, Gordon A

2017-01-01

Direct realisation of force, traceable to fundamental constants via electromagnetic balances, is a key goal of the proposed redefinition of the international system of units (SI). This will allow small force metrology to be performed using an electrostatic force balance (EFB) rather than subdivision of larger forces. Such a balance uses the electrostatic force across a capacitor to balance an external force. In this paper we model the capacitance of a concentric cylinder EFB design as a function of the displacement of its free electrode, accounting for the arcuate motion produced by parallelogram linkages commonly used in EFB mechanisms. From this model we suggest new fitting procedures to reduce uncertainties arising from non-linear motion as well as methods to identify misalignment of the mechanism. Experimental studies on both a test capacitor and the NIST EFB validate the model. (paper)

Influence of forced internal air circulation on airflow distribution and heat transfer in a gas double-dynamic solid-state fermentation bioreactor.

Science.gov (United States)

Chen, Hongzhang; Qin, Lanzhi; Li, Hongqiang

2014-02-01

Internal air circulation affects the temperature field distribution in a gas double-dynamic solid-state fermentation bioreactor (GDSFB). To enhance heat transfer through strengthening internal air circulation in a GDSFB, we put an air distribution plate (ADP) into the bioreactor and studied the effects of forced internal air circulation on airflow, heat transfer, and cellulase activity of Trichoderma viride L3. Results showed that ADP could help form a steady and uniform airflow distribution, and with gas-guide tubes, air reversal was formed inside the bioreactor, thus resulting in a smaller temperature difference between medium and air by enhancing convective heat transfer inside the bioreactor. Using an ADP of 5.35 % aperture ratio caused a 1 °C decrease in the average temperature difference during the solid-state fermentation process of T. viride L3. Meanwhile, the cellulase activity of T. viride L3 increased by 13.5 %. The best heat-transfer effect was attained when using an ADP of 5.35 % aperture ratio and setting the fan power to 125 V (4.81 W) in the gas double-dynamic solid-state fermentation (GDSF) process. An option of suitable aperture ratio and fan power may be conducive to ADPs' industrial amplification.

Search Results | Page 176 | IDRC - International Development ...

International Development Research Centre (IDRC) Digital Library (Canada)

... (FBOs) are one of the driving forces for political and social change. ... In this project, IDRC will partner with the Norman Paterson School of International Affairs (NPSIA) in furthering a program of research on international human rights. Project.

Controlling Casimir force via coherent driving field

Science.gov (United States)

Ahmad, Rashid; Abbas, Muqaddar; Ahmad, Iftikhar; Qamar, Sajid

2016-04-01

A four level atom-field configuration is used to investigate the coherent control of Casimir force between two identical plates made up of chiral atomic media and separated by vacuum of width d. The electromagnetic chirality-induced negative refraction is obtained via atomic coherence. The behavior of Casimir force is investigated using Casimir-Lifshitz formula. It is noticed that Casimir force can be switched from repulsive to attractive and vice versa via coherent control of the driving field. This switching feature provides new possibilities of using the repulsive Casimir force in the development of new emerging technologies, such as, micro-electro-mechanical and nano-electro-mechanical systems, i.e., MEMS and NEMS, respectively.

An investigation of structural design methodology for HTGR reactor internals with ceramic materials (Contract research)

International Nuclear Information System (INIS)

Sumita, Junya; Shibata, Taiju; Nakagawa, Shigeaki; Iyoku, Tatsuo; Sawa, Kazuhiro

2008-03-01

To advance the performance and safety of HTGR, heat-resistant ceramic materials are expected to be used as reactor internals of HTGR. C/C composite and superplastic zirconia are the promising materials for this purpose. In order to use these new materials as reactor internals in HTGR, it is necessary to establish a structure design method to guarantee the structural integrity under environmental and load conditions. Therefore, C/C composite expected as reactor internals of VHTR is focused and an investigation on the structural design method applicable to the C/C composite and a basic applicability of the C/C composite to representative structures of HTGR were carried out in this report. As the results, it is found that the competing risk theory for the strength evaluation of the C/C composite is applicable to design method and C/C composite is expected to be used as reactor internals of HTGR. (author)

Afghanistan’s Local War: Building Local Defense Forces

Science.gov (United States)

2010-01-01

Afghanistan’s Local War: Building Local Defense Forces economic and other development conditions. As the Nobel Prize- winning economist Amartya Sen ...strengthen warlords 9 Amartya Sen , Development as Freedom, New York: Anchor Books, 2000, p. 11. Mitigating Risks 77 • weaken central government forces...Taliban Afghanistan, Bonn: Bonn International Center for Conversion, 2002. Sen , Amartya , Development as Freedom, New York: Anchor Books, 2000. Shahrani

8. International Conference on Pulse Investigations in Chemistry, Biology and Physics - PULS'2008. Abstracts

International Nuclear Information System (INIS)

2008-01-01

The Report comprises abstracts of 68 communications (oral and posters) presented during the 8. International Conference on Pulse Investigations in Chemistry, Biology and Physics - PULS'2008, held on September 6 - 12, 2008 in Cracow. Presentations cover a variety of research fields representing different fields of pulse radiolysis in chemistry, biology and physics

8. International Conference on Pulse Investigations in Chemistry, Biology and Physics - PULS'2008. Abstracts

Energy Technology Data Exchange (ETDEWEB)

NONE

2008-07-01

The Report comprises abstracts of 68 communications (oral and posters) presented during the 8. International Conference on Pulse Investigations in Chemistry, Biology and Physics - PULS'2008, held on September 6 - 12, 2008 in Cracow. Presentations cover a variety of research fields representing different fields of pulse radiolysis in chemistry, biology and physics.

Estimation of the forces acting on the tibiofemoral joint during knee extension exercises

Directory of Open Access Journals (Sweden)

Rodrigo Rico Bini

2008-02-01

Full Text Available http://dx.doi.org/10.5007/1980-0037.2008v10n1p35 The objectives of this study were to: (1 evaluate the resistive torque of an open kinetic chain strength-training machine for performing knee extensions, and (2 perform an analysis estimating internal forces in the tibiofemoral joint. During a fi rst phase of the study, measurements were taken of the machine under analysis (external forces, and then calculations were performed to estimate forces on the lower limb (internal forces. Equations were defi ned to calculate human force (HF, and the moment of muscular force (MMF. Perpendicular muscular force (MFp and joint force (JFp, axial muscular force (MF” and joint force (JF”, and total muscular force (MF and joint force (JF were all calculated. Five knee angles were analyzed (zero, 30, 45, 60, and 90 degrees. A reduction was observed in HF at higher knee angles, while MF and JF also increased at the same time. HF was always lower than the load selected on the machine, which indicates a reduced overload imposed by the machine. The reduction observed in MFp and JFp at higher knee angles indicates a lower tendency to shear the tibia in relation to the femur. At the same time, there was an increase in JF” due to higher MF”. The biomechanical model proposed in this study has shown itself adequate for the day-to-day needs of professionals who supervise orient strength training.

Physicists' Forced Migrations under Hitler

Science.gov (United States)

Beyerchen, Alan

2011-03-01

When the Nazis came to power in early 1933 they initiated formal and informal measures that forced Jews and political opponents from public institutions such as universities. Some physicists retired and others went into industry, but most emigrated. International communication and contact made emigration a viable option despite the desperate economic times in the Great Depression. Another wave of emigrations followed the annexation of Austria in 1938. Individual cases as well as general patterns of migration and adaptation to new environments will be examined in this presentation. One important result of the forced migrations was that many of the physicists expelled under Hitler played important roles in strengthening physics elsewhere, often on the Allied side in World War II.

Investigation of combined free and forced convection in a 2 x 6 rod bundle during controlled flow transients

International Nuclear Information System (INIS)

Bates, J.M.; Khan, E.U.

1980-10-01

An experimental study was performed to obtain local fluid velocity and temperature measurements in the mixed (combined free and forced) convection regime for specific flow coastdown transients. A brief investigation of steady-state flows for the purely free-convection regime was also completed. The study was performed using an electrically heated 2 x 6 rod bundle contained in a flow housing. In addition a transient data base was obtained for evaluating the COBRA-WC thermal-hydraulic computer program

Design and construction of a heat stage for investigations of samples by atomic force microscopy above ambient temperatures

DEFF Research Database (Denmark)

Bækmark, Thomas Rosleff; Bjørnholm, Thomas; Mouritsen, Ole G.

1997-01-01

The construction from simple and cheap commercially available parts of a miniature heat stage for the direct heating of samples studied with a commercially available optical-lever-detection atomic force microscope is reported. We demonstrate that by using this heat stage, atomic resolution can...... be obtained on highly oriented pyrolytic graphite at 52 °C. The heat stage is of potential use for the investigation of biological material at physiological temperatures. ©1997 American Institute of Physics....

Experimental investigation of the influence of internal frames on the vibroacoustic behavior of a stiffened cylindrical shell using wavenumber analysis

Science.gov (United States)

Meyer, V.; Maxit, L.; Renou, Y.; Audoly, C.

2017-09-01

The understanding of the influence of non-axisymmetric internal frames on the vibroacoustic behavior of a stiffened cylindrical shell is of high interest for the naval or aeronautic industries. Several numerical studies have shown that the non-axisymmetric internal frame can increase the radiation efficiency significantly in the case of a mechanical point force. However, less attention has been paid to the experimental verification of this statement. That is why this paper proposes to compare the radiation efficiency estimated experimentally for a stiffened cylindrical shell with and without internal frames. The experimental process is based on scanning laser vibrometer measurements of the vibrations on the surface of the shell. A transform of the vibratory field in the wavenumber domain is then performed. It allows estimating the far-field radiated pressure with the stationary phase theorem. An increase of the radiation efficiency is observed in the low frequencies. Analysis of the velocity field in the physical and wavenumber spaces allows highlighting the coupling of the circumferential orders at the origin of the increase in the radiation efficiency.

Universal spin-momentum locked optical forces

Energy Technology Data Exchange (ETDEWEB)

Kalhor, Farid [Department of Electrical and Computer Engineering, University of Alberta, Edmonton, Alberta T6G 1H9 (Canada); Thundat, Thomas [Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta T6G 1H9 (Canada); Jacob, Zubin, E-mail: zjacob@purdue.edu [Department of Electrical and Computer Engineering, University of Alberta, Edmonton, Alberta T6G 1H9 (Canada); Birck Nanotechnology Center, Department of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47906 (United States)

2016-02-08

Evanescent electromagnetic waves possess spin-momentum locking, where the direction of propagation (momentum) is locked to the inherent polarization of the wave (transverse spin). We study the optical forces arising from this universal phenomenon and show that the fundamental origin of recently reported non-trivial optical chiral forces is spin-momentum locking. For evanescent waves, we show that the direction of energy flow, the direction of decay, and the direction of spin follow a right hand rule for three different cases of total internal reflection, surface plasmon polaritons, and HE{sub 11} mode of an optical fiber. Furthermore, we explain how the recently reported phenomena of lateral optical force on chiral and achiral particles are caused by the transverse spin of the evanescent field and the spin-momentum locking phenomenon. Finally, we propose an experiment to identify the unique lateral forces arising from the transverse spin in the optical fiber and point to fundamental differences of the spin density from the well-known orbital angular momentum of light. Our work presents a unified view on spin-momentum locking and how it affects optical forces on chiral and achiral particles.

Application of orthodontic forces prior to autotransplantation - case reports.

Science.gov (United States)

Cho, J-H; Hwang, H-S; Chang, H-S; Hwang, Y-C

2013-02-01

This case report describes the successful autotransplantation of mandibular molars after application of orthodontic forces and discusses the advantages of this technique, that is, pre-application of an orthodontic force for autotransplantation. After clinical and radiographic examination, autotransplantation was planned with the patient's written informed consent. An orthodontic force was applied, and the surgical procedure was performed after tooth mobility had increased. Root canal treatment was performed within 2 weeks of autotransplantation. At the 1-year follow-up, the transplanted teeth revealed asymptomatic and healthy periodontal conditions. Autotransplantation is the surgical movement of a tooth from its original location to another site. The pre-application of orthodontic force technique was recently introduced for autogenous tooth transplantation. Pre-application of an orthodontic force may be a useful treatment option for autotransplantation. © 2012 International Endodontic Journal.

The everyday violence of forced displacement : community, memory and identity politics among Kurdish internal forced migrants in Turkey

NARCIS (Netherlands)

Geerse, M.T.

2011-01-01

Kurds in Turkey: the everyday violence of their forced displacement. Roughly fifteen years ago, more than one million Kurds were forcibly displaced from their villages in Southeast Turkey, mostly by Turkish security troops, who were engaged in a violent struggle with the PKK, an armed organization

What are the minimum requirements for ketogenic diet services in resource-limited regions? Recommendations from the International League Against Epilepsy Task Force for Dietary Therapy.

Science.gov (United States)

Kossoff, Eric H; Al-Macki, Nabil; Cervenka, Mackenzie C; Kim, Heung D; Liao, Jianxiang; Megaw, Katherine; Nathan, Janak K; Raimann, Ximena; Rivera, Rocio; Wiemer-Kruel, Adelheid; Williams, Emma; Zupec-Kania, Beth A

2015-09-01

Despite the increasing use of dietary therapies for children and adults with refractory epilepsy, the availability of these treatments in developing countries with limited resources remains suboptimal. One possible contributory factor may be the costs. There is often reported a significant perceived need for a large ketogenic diet team, supplements, laboratory studies, and follow-up visits to provide this treatment. The 2009 Epilepsia Consensus Statement described ideal requirements for a ketogenic diet center, but in some situations this is not feasible. As a result, the International League Against Epilepsy (ILAE) Task Force on Dietary Therapy was asked to convene and provide practical, cost-effective recommendations for new ketogenic diet centers in resource-limited regions of the world. Wiley Periodicals, Inc. © 2015 International League Against Epilepsy.

Investigation of water entry impact forces on airborne-launched AUVs

Directory of Open Access Journals (Sweden)

Duo Qi

2016-01-01

Full Text Available Airborne-launched AUVs withstand great fluid impact force at the early stage when entering the water, which may cause damage to their structure and inner components in severe cases. Due to their large volume and mass, the major challenge involved in conducting experiments to measure the water entry impacts on real-life AUVs is the high demand for the experimental devices, finding a suitable site, and the cost of the experiments. Using a gas gun as launching device, water entry experiments using a full-size AUV model are conducted under various conditions. The axial and radial force changes that occur during the water entry process are obtained, and some accompanied phenomena such as cavitation and turnover under different water entry conditions are observed. Computational fluid dynamics (CFD is used to simulate the water entry process of airborne-launched AUVs. The simulation results fit well with the experimental data, the latter of which show that both the water entry velocity and entry angle have a great influence on the impact load during the water entry process. These data can provide valuable reference information for AUV structure design and launch condition selection.

Hydrodynamic investigation of a self-propelled robotic fish based on a force-feedback control method

International Nuclear Information System (INIS)

Wen, L; Wang, T M; Liang, J H; Wu, G H

2012-01-01

We implement a mackerel (Scomber scombrus) body-shaped robot, programmed to display the three most typical body/caudal fin undulatory kinematics (i.e. anguilliform, carangiform and thunniform), in order to biomimetically investigate hydrodynamic issues not easily tackled experimentally with live fish. The robotic mackerel, mounted on a servo towing system and initially at rest, can determine its self-propelled speed by measuring the external force acting upon it and allowing for the simultaneous measurement of power, flow field and self-propelled speed. Experimental results showed that the robotic swimmer with thunniform kinematics achieved a faster final swimming speed (St = 0.424) relative to those with carangiform (St = 0.43) and anguilliform kinematics (St = 0.55). The thrust efficiency, estimated from a digital particle image velocimetry (DPIV) flow field, showed that the robotic swimmer with thunniform kinematics is more efficient (47.3%) than those with carangiform (31.4%) and anguilliform kinematics (26.6%). Furthermore, the DPIV measurements illustrate that the large-scale characteristics of the flow pattern generated by the robotic swimmer with both anguilliform and carangiform kinematics were wedge-like, double-row wake structures. Additionally, a typical single-row reverse Karman vortex was produced by the robotic swimmer using thunniform kinematics. Finally, we discuss this novel force-feedback-controlled experimental method, and review the relative self-propelled hydrodynamic results of the robot when utilizing the three types of undulatory kinematics. (paper)

Force sharing and other collaborative strategies in a dyadic force perception task

Science.gov (United States)

Tatti, Fabio

2018-01-01

When several persons perform a physical task jointly, such as transporting an object together, the interaction force that each person experiences is the sum of the forces applied by all other persons on the same object. Therefore, there is a fundamental ambiguity about the origin of the force that each person experiences. This study investigated the ability of a dyad (two persons) to identify the direction of a small force produced by a haptic device and applied to a jointly held object. In this particular task, the dyad might split the force produced by the haptic device (the external force) in an infinite number of ways, depending on how the two partners interacted physically. A major objective of this study was to understand how the two partners coordinated their action to perceive the direction of the third force that was applied to the jointly held object. This study included a condition where each participant responded independently and another one where the two participants had to agree upon a single negotiated response. The results showed a broad range of behaviors. In general, the external force was not split in a way that would maximize the joint performance. In fact, the external force was often split very unequally, leaving one person without information about the external force. However, the performance was better than expected in this case, which led to the discovery of an unanticipated strategy whereby the person who took all the force transmitted this information to the partner by moving the jointly held object. When the dyad could negotiate the response, we found that the participant with less force information tended to switch his or her response more often. PMID:29474433

Experimental investigation and modelling of surface roughness and resultant cutting force in hard turning of AISI H13 Steel

Science.gov (United States)

Boy, M.; Yaşar, N.; Çiftçi, İ.

2016-11-01

In recent years, turning of hardened steels has replaced grinding for finishing operations. This process is compared to grinding operations; hard turning has higher material removal rates, the possibility of greater process flexibility, lower equipment costs, and shorter setup time. CBN or ceramic cutting tools are widely used hard part machining. For successful application of hard turning, selection of suitable cutting parameters for a given cutting tool is an important step. For this purpose, an experimental investigation was conducted to determine the effects of cutting tool edge geometry, feed rate and cutting speed on surface roughness and resultant cutting force in hard turning of AISI H13 steel with ceramic cutting tools. Machining experiments were conducted in a CNC lathe based on Taguchi experimental design (L16) in different levels of cutting parameters. In the experiments, a Kistler 9257 B, three cutting force components (Fc, Ff and Fr) piezoelectric dynamometer was used to measure cutting forces. Surface roughness measurements were performed by using a Mahrsurf PS1 device. For statistical analysis, analysis of variance has been performed and mathematical model have been developed for surface roughness and resultant cutting forces. The analysis of variance results showed that the cutting edge geometry, cutting speed and feed rate were the most significant factors on resultant cutting force while the cutting edge geometry and feed rate were the most significant factor for the surface roughness. The regression analysis was applied to predict the outcomes of the experiment. The predicted values and measured values were very close to each other. Afterwards a confirmation tests were performed to make a comparison between the predicted results and the measured results. According to the confirmation test results, measured values are within the 95% confidence interval.

On Effective Radiative Forcing of Partial Internally and Externally Mixed Aerosols and Their Effects on Global Climate

Science.gov (United States)

Zhou, Chen; Zhang, Hua; Zhao, Shuyun; Li, Jiangnan

2018-01-01

The total effective radiative forcing (ERF) due to partial internally mixed (PIM) and externally mixed (EM) anthropogenic aerosols, as well as their climatic effects since the year of 1850, was evaluated and compared using the aerosol-climate online coupled model of BCC_AGCM2.0_CUACE/Aero. The influences of internal mixing (IM) on aerosol hygroscopicity parameter, optical properties, and concentration were considered. Generally, IM could markedly weaken the negative ERF and cooling effects of anthropogenic aerosols. The global annual mean ERF of EM anthropogenic aerosols from 1850 to 2010 was -1.87 W m-2, of which the aerosol-radiation interactive ERF (ERFari) and aerosol-cloud interactive ERF (ERFaci) were -0.49 and -1.38 W m-2, respectively. The global annual mean ERF due to PIM anthropogenic aerosols from 1850 to 2010 was -1.23 W m-2, with ERFari and ERFaci of -0.23 and -1.01 W m-2, respectively. The global annual mean surface temperature and water evaporation and precipitation were reduced by 1.74 K and 0.14 mm d-1 for EM scheme and 1.28 K and 0.11 mm d-1 for PIM scheme, respectively. However, the relative humidity near the surface was slightly increased for both mixing cases. The Intertropical Convergence Zone was southwardly shifted for both EM and PIM cases but was less southwardly shifted in PIM scheme due to the less reduction in atmospheric temperature in the midlatitude and low latitude of the Northern Hemisphere.

Gender Integration and the Swedish Armed Forces

DEFF Research Database (Denmark)

Gustafsson, Daniel Marcus Sunil

This paper discusses different gender aspects of the Swedish Armed Forces with specific references to sexual harassment and prostitution. By using the concept of Hegemonic Masculinity, sexual harassment of the women in the Swedish Armed Forces is explained in terms of a need of the men within...... the organisation to reinforce the notion of women as inferior and subordinate to men, whereby the external hegemony is believed to be restored. Likewise, male Swedish peacekeepers’ demand for prostitution during international peacekeeping missions is explained in terms of a need to confirm manhood and as homo...

International workshop on site investigation and evaluation based on the siting process in Sweden

International Nuclear Information System (INIS)

Andersson, Johan; Stroem, A.

2001-06-01

SKB's goal is to commence surface based site investigations in 2002. Extensive preparations are now being made for this transition to the next phase in the siting process for the deep repository for spent nuclear fuel. The purpose of the international workshop on site characterisation held at Aespoe April 2001 was to: present the SKB site investigation and evaluation programme to a group of international experts; discuss whether the available toolbox of investigation methods for surface based site investigations is appropriate and state-of-the-art in an international perspective; and by working group sessions discuss the level of ambition in the programme for site investigation for each discipline. This report summarises the conclusions of the workshop in general terms. Many of the detailed comments and ideas obtained at the workshop have already inspired and will also directly inspire the on-going planning work for site characterisation. The core activity at the workshop was the work performed by working groups. They addressed what should be considered for a site characterisation programme, based on the generic planning made so far by SKB. The working groups also outlined site specific characterisation programmes for the sites suggested by SKB. The tasks were strictly confined to technical and scientific modelling issues. The working group chairmen presented the working group results at the workshop and have also submitted short memos to SKB. The present document is a compilation of these memos. The SKB generic programme as presented in the existing top level documents, 'Requirements and Criteria and Overall Programme', received general endorsement and was appreciated for being comprehensive and systematic. For example, it contains comprehensive lists of parameters to be measured. However, there is need for prioritisation and sequencing. This is actually included in the current planning process at SKB where the generic programme later this year will be adapted to

Langmuir- Blodgett layers of amphiphilic molecules investigated by Atomic Force Microscopy

NARCIS (Netherlands)

Zdravkova, Aneliya Nikolova

2007-01-01

Langmuir - Blodgett technique and Atomic Force Microscopy were used to study the phase behaviour of organic molecules (fatty alcohols and monoacid saturated triglycerides) at air-water and air-solid interfaces. The structure of binary mixed LB monolayers of fatty alcohols was reported. The

Theoretical Investigation of Peak-Delay Force Reduction for Caissons Exposed to Non-breaking Short-Crested Waves

DEFF Research Database (Denmark)

Burcharth, H. F.; Liu, Z.

In nature coastal structures are exposed to oblique short-crested waves. The effect of wave incident angle on total wave force on a long caisson are twofold. The one is the force reduction due to the reduction of instantaneous point pressure on the caisson, named point-pressure force reduction....... The other is the force reduction due to the fact that the peak pressures do not occur simultaneously along the caisson, named peak-delay force reduction. These two reduction effects can also be expected with short-crested waves, as the short-crestedness of waves means the spreading of wave energy over...... a range of incident angles. The peak-delay force reduction, i.e. no simultaneous peak along caisson, is of particular interest because the equipment improvement in construction enables the building of considerably long caissons. In Japan length of caissons exceeds often 100m. This paper will concentrate...

Experimental Investigation of 2:1 and 3:1 Internal Resonances in Nonlinear MEMS Arch Resonators

KAUST Repository

Ramini, Abdallah; Hajjaj, Amal Z.; Younis, Mohammad I.

2016-01-01

We demonstrate experimentally internal resonances in MEMS resonators. The investigation is conducted on in-plane MEMS arch resonators fabricated with a highly doped silicon. The resonators are actuated electrostatically and their stiffness are tuned by electrothermal loading by passing an electrical current though the microstructures. We show that through this tuning, the ratio of the various resonance frequencies can be varied and set at certain ratios. Particularly, we adjust the resonance frequencies of two different vibrational modes to 2:1 and 3:1. Finally, we validate the internal resonances at these ratios through frequency-response curves and FFTs.

Experimental Investigation of 2:1 and 3:1 Internal Resonances in Nonlinear MEMS Arch Resonators

KAUST Repository

Ramini, Abdallah

2016-12-05

We demonstrate experimentally internal resonances in MEMS resonators. The investigation is conducted on in-plane MEMS arch resonators fabricated with a highly doped silicon. The resonators are actuated electrostatically and their stiffness are tuned by electrothermal loading by passing an electrical current though the microstructures. We show that through this tuning, the ratio of the various resonance frequencies can be varied and set at certain ratios. Particularly, we adjust the resonance frequencies of two different vibrational modes to 2:1 and 3:1. Finally, we validate the internal resonances at these ratios through frequency-response curves and FFTs.

Numerical and experimental investigation of melting with internal heat generation within cylindrical enclosures

Energy Technology Data Exchange (ETDEWEB)

Amber Shrivastava; Brian Williams; Ali S. Siahpush; Bruce Savage; John Crepeau

2014-06-01

There have been significant efforts by the heat transfer community to investigate the melting phenomenon of materials. These efforts have included the analytical development of equations to represent melting, numerical development of computer codes to assist in modeling the phenomena, and collection of experimental data. The understanding of the melting phenomenon has application in several areas of interest, for example, the melting of a Phase Change Material (PCM) used as a thermal storage medium as well as the melting of the fuel bundle in a nuclear power plant during an accident scenario. The objective of this research is two-fold. First a numerical investigation, using computational fluid dynamics (CFD), of melting with internal heat generation for a vertical cylindrical geometry is presented. Second, to the best of authors knowledge, there are very limited number of engineering experimental results available for the case of melting with Internal Heat Generation (IHG). An experiment was performed to produce such data using resistive, or Joule, heating as the IHG mechanism. The numerical results are compared against the experimental results and showed favorable correlation. Uncertainties in the numerical and experimental analysis are discussed. Based on the numerical and experimental analysis, recommendations are made for future work.

Physical sciences research plans for the International Space Station

Science.gov (United States)

Trinh, E. H.

2003-01-01

The restructuring of the research capabilities of the International Space Station has forced a reassessment of the Physical Sciences research plans and a re-targeting of the major scientific thrusts. The combination of already selected peer-reviewed flight investigations with the initiation of new research and technology programs will allow the maximization of the ISS scientific and technological potential. Fundamental and applied research will use a combination of ISS-based facilities, ground-based activities, and other experimental platforms to address issues impacting fundamental knowledge, industrial and medical applications on Earth, and the technology required for human space exploration. The current flight investigation research plan shows a large number of principal investigators selected to use the remaining planned research facilities. c2003 American Institute of Aeronautics and Astronautics. Published by Elsevier Science Ltd. All rights reserved.

Spectroscopic investigation of the vibrational quasi-continuum arising from internal rotation of a methyl group

Energy Technology Data Exchange (ETDEWEB)

Hougen, J.T. [NIST, Gaithersburg, MD (United States)

1993-12-01

The goal of this project is to use spectroscopic techniques to investigate in detail phenomena involving the vibrational quasi-continuum in a simple physical system. Acetaldehyde was chosen for the study because: (i) methyl groups have been suggested to be important promotors of intramolecular vibrational relaxation, (ii) the internal rotation of a methyl group is an easily describle large-amplitude motion, which should retain its simple character even at high levels of excitation, and (iii) the aldehyde carbonyl group offers the possibility of both vibrational and electronic probing. The present investigation of the ground electronic state has three parts: (1) understanding the {open_quotes}isolated{close_quotes} internal-rotation motion below, at, and above the top of the torsional barrier, (2) understanding in detail traditional (bond stretching and bending) vibrational fundamental and overtone states, and (3) understanding interactions involving states with multiquantum excitations of at least one of these two kinds of motion.

Biodegradable Piezoelectric Force Sensor.

Science.gov (United States)

Curry, Eli J; Ke, Kai; Chorsi, Meysam T; Wrobel, Kinga S; Miller, Albert N; Patel, Avi; Kim, Insoo; Feng, Jianlin; Yue, Lixia; Wu, Qian; Kuo, Chia-Ling; Lo, Kevin W-H; Laurencin, Cato T; Ilies, Horea; Purohit, Prashant K; Nguyen, Thanh D

2018-01-30

Measuring vital physiological pressures is important for monitoring health status, preventing the buildup of dangerous internal forces in impaired organs, and enabling novel approaches of using mechanical stimulation for tissue regeneration. Pressure sensors are often required to be implanted and directly integrated with native soft biological systems. Therefore, the devices should be flexible and at the same time biodegradable to avoid invasive removal surgery that can damage directly interfaced tissues. Despite recent achievements in degradable electronic devices, there is still a tremendous need to develop a force sensor which only relies on safe medical materials and requires no complex fabrication process to provide accurate information on important biophysiological forces. Here, we present a strategy for material processing, electromechanical analysis, device fabrication, and assessment of a piezoelectric Poly-l-lactide (PLLA) polymer to create a biodegradable, biocompatible piezoelectric force sensor, which only employs medical materials used commonly in Food and Drug Administration-approved implants, for the monitoring of biological forces. We show the sensor can precisely measure pressures in a wide range of 0-18 kPa and sustain a reliable performance for a period of 4 d in an aqueous environment. We also demonstrate this PLLA piezoelectric sensor can be implanted inside the abdominal cavity of a mouse to monitor the pressure of diaphragmatic contraction. This piezoelectric sensor offers an appealing alternative to present biodegradable electronic devices for the monitoring of intraorgan pressures. The sensor can be integrated with tissues and organs, forming self-sensing bionic systems to enable many exciting applications in regenerative medicine, drug delivery, and medical devices.

External and internal structure of weevils (Insecta: Coleoptera) investigated with phase-contrast X-ray imaging

International Nuclear Information System (INIS)

Hoennicke, M.G.; Cusatis, C.; Rigon, L.; Menk, R.-H.; Arfelli, F.; Foerster, L.A.; Rosado-Neto, G.H.

2010-01-01

Weevils (Coleoptera: Curculionidae) are identified by the external structure (dorsal, ventral and lateral features) and also by internal structure. The genitalia can be used to distinguish the sex and to identify the insects when the external structure appears identical. For this purpose, a destructive dissecting microscopy procedure is usually employed. In this paper, phase contrast X-ray imaging (radiography and tomography) is employed to investigate the internal structure (genitalia) of two entire species of weevils that presents very similar external structures (Sitophilus oryzae and Sitophilus zeamais). The detection of features, which looks like the genital structure, shows that such non-destructive technique could be used as an alternative method for identification of insects. This method is especially useful in examining the internal features of precious species from museum collections, as already described in the recent literature.

COMPETITIVENESS IN SERVICES, DRIVING FORCE OF ECONOMIC DEVELOPMENT

OpenAIRE

RAMONA PÎRVU; MARIA DANATIE ENESCU

2012-01-01

The competitiveness of a nation is ensured by the profitable activity of firms. They strengthen their position in the domestic and international markets through global strategies whose purpose is to increase productivity and maintain it at a high level. For this, the company must take into account both the internal economic environment which ensures operating conditions and the external economic environment’s development. The five competitive forces determine the industry’s profitability beca...

[Investigating work, age, health and work participation in the ageing work force in Germany].

Science.gov (United States)

Ebener, M; Hasselhorn, H M

2015-04-01

Working life in Germany is changing. The work force is ageing and the number of people available to the labour market will - from now on - shrink considerably. Prospectively, people will have to work longer; but still today, most people leave employment long before reaching official retirement age. What are the reasons for this? In this report, a conceptual framework and the German lidA Cohort Study are presented. The "lidA conceptual framework on work, age, health and work participation" visualises determinants of employment (11 "domains") in higher working age, e. g., "work", "health", "social status" and "life style". The framework reveals 4 key characteristics of withdrawal from work: leaving working life is the result of an interplay of different domains (complexity); (early) retirement is a process with in part early determinants in the life course (processual character); retirement has a strong individual component (individuality); retirement is embedded in a strong structural frame (structure). On the basis of this framework, the "lidA Cohort Study on work, age, health and work participation" (www.lida-studie.de) investigates long-term effects of work on health and work participation in the ageing work force in Germany. It is the only large study in Germany operationalising the concept of employability in a broad interdisciplinary approach. Employees subject to social security and born in 1959 or in 1965 will be interviewed (CAPI) every 3 years (N[wave 1]=6 585, N[wave 2]=4 244) and their data will be linked (where consented) with social security data covering employment history and with health insurance data. The study design ("Schaie's most efficient design") allows for a tri-factor model that isolates the impact of age, cohort and time. In 2014, the second wave was completed. In the coming years lidA will analyse the association of work, health and work participation, and identify age as well as generation differences. lidA will investigate the

Report of the Fermilab ILC Citizens' Task Force

Energy Technology Data Exchange (ETDEWEB)

None

2008-06-01

Fermi National Accelerator Laboratory convened the ILC Citizens' Task Force to provide guidance and advice to the laboratory to ensure that community concerns and ideas are included in all public aspects of planning and design for a proposed future accelerator, the International Linear Collider. In this report, the members of the Task Force describe the process they used to gather and analyze information on all aspects of the proposed accelerator and its potential location at Fermilab in northern Illinois. They present the conclusions and recommendations they reached as a result of the learning process and their subsequent discussions and deliberations. While the Task Force was charged to provide guidance on the ILC, it became clear during the process that the high cost of the proposed accelerator made a near-term start for the project at Fermilab unlikely. Nevertheless, based on a year of extensive learning and dialogue, the Task Force developed a series of recommendations for Fermilab to consider as the laboratory develops all successor projects to the Tevatron. The Task Force recognizes that bringing a next-generation particle physics project to Fermilab will require both a large international effort and the support of the local community. While the Task Force developed its recommendations in response to the parameters of a future ILC, the principles they set forth apply directly to any large project that may be conceived at Fermilab, or at other laboratories, in the future. With this report, the Task Force fulfills its task of guiding Fermilab from the perspective of the local community on how to move forward with a large-scale project while building positive relationships with surrounding communities. The report summarizes the benefits, concerns and potential impacts of bringing a large-scale scientific project to northern Illinois.

Force Protection and Command Relationships: Who's Responsible

National Research Council Canada - National Science Library

Moller, James

1998-01-01

.... This monograph analyzes the joint force protection program by investigating the terms: command, chain of command, command relationship, and how these terms authorize and empower a commander to implement this program across the joint force...

Globally Coupled Chaotic Maps with Constant Force

International Nuclear Information System (INIS)

Li Jinghui

2008-01-01

We investigate the motion of the globally coupled maps (logistic map) with a constant force. It is shown that the constant force can cause multi-synchronization for the globally coupled chaotic maps studied by us.

Microscopic investigation of InGaN/GaN heterostructure laser diode degradation using Kelvin probe force microscopy

International Nuclear Information System (INIS)

Lochthofen, A; Mertin, W; Bacher, G; Furitsch, M; Bruederl, G; Strauss, U; Haerle, V

2008-01-01

We report on Kelvin probe force microscopy (KPFM) measurements on fresh and artificially aged InGaN/GaN laser test structures. In the case of an unbiased laser diode, a comparison of the surface potential between a fresh and a stressed laser diode shows a pronounced modification of the laser facet due to the aging process. Performing KPFM measurements under forward bias, a correlation between the macroscopic I-V characteristics and the microscopic voltage drop across the heterostructure layer sequence is found. This clearly demonstrates the potential of KPFM for investigating InGaN/GaN laser diode degradation

STRATEGIC PRIORITIES FOR THE INTERNAL MIGRATION PROCESSES REGULATION IN UKRAINE

Directory of Open Access Journals (Sweden)

Olga Balueva

2018-01-01

Full Text Available As the result of the annexation of the Crimea and Donbass military conflict, there was an emergence of forced migration. It ought to be emphasized that today issues related to addressing problems of internally displaced persons (IDPs, are relevant and require an integrated approach. The increase in the number of IDPs in the country raises the issue of identifying the strategic priorities of the state policy. The purpose of this research is to formulate strategic priorities of the state policy of support for IDPs’. The subject of the study is theoretical and methodological principles of the state policy to support IDPs. The research methodology includes a set of scientific research methods that provide identifying the strategic priorities of the state policy for IDPs’ support, developing effective mechanisms for these priorities achievement, and conceptual vision of solving IDPs’ problems. In the course of investigations, the following methods are used: analysis while studying the main problems of internally displaced persons; logical synthesis and synthesis while drawing conclusions. Results. Scientific novelty of the article. In the article, the conceptual foundations of the IDPs support have been formed, an attention has been focused on the feasibility of using a strategic approach, which involves the formation and implementation of a set of strategically oriented measures aimed at solving the most acute issues and matters related to internal forced migration, directing the IDPs potential and internally displaced businesses to strengthen local communities and social and economic development of the resettlement territories. The main stages and conceptual foundations for the Strategy formation on the IDPs support have been proposed. The strategy is based on an integrated approach to addressing IDPs and internally displaced businesses, taking into account the interests of host communities. Practical implications. The result of the Strategy

A Snapshot of Serial Rape: An Investigation of Criminal Sophistication and Use of Force on Victim Injury and Severity of the Assault.

Science.gov (United States)

de Heer, Brooke

2016-02-01

Prior research on rapes reported to law enforcement has identified criminal sophistication and the use of force against the victim as possible unique identifiers to serial rape versus one-time rape. This study sought to contribute to the current literature on reported serial rape by investigating how the level of criminal sophistication of the rapist and use of force used were associated with two important outcomes of rape: victim injury and overall severity of the assault. In addition, it was evaluated whether rapist and victim ethnicity affected these relationships. A nation-wide sample of serial rape cases reported to law enforcement collected by the Federal Bureau of Investigation (FBI) was analyzed (108 rapists, 543 victims). Results indicated that serial rapists typically used a limited amount of force against the victim and displayed a high degree of criminal sophistication. In addition, the more criminally sophisticated the perpetrator was, the more sexual acts he performed on his victim. Finally, rapes between a White rapist and White victim were found to exhibit higher levels of criminal sophistication and were more severe in terms of number and types of sexual acts committed. These findings provide a more in-depth understanding of serial rape that can inform both academics and practitioners in the field about contributors to victim injury and severity of the assault. © The Author(s) 2014.

Effect of fatigue on force production and force application technique during repeated sprints.

Science.gov (United States)

Morin, Jean-Benoit; Samozino, Pierre; Edouard, Pascal; Tomazin, Katja

2011-10-13

We investigated the changes in the technical ability of force application/orientation against the ground vs. the physical capability of total force production after a multiple-set repeated sprints series. Twelve male physical education students familiar with sprint running performed four sets of five 6-s sprints (24s of passive rest between sprints, 3min between sets). Sprints were performed from a standing start on an instrumented treadmill, allowing the computation of vertical (F(V)), net horizontal (F(H)) and total (F(Tot)) ground reaction forces for each step. Furthermore, the ratio of forces was calculated as RF=F(H)F(Tot)(-1), and the index of force application technique (D(RF)) representing the decrement in RF with increase in speed was computed as the slope of the linear RF-speed relationship. Changes between pre- (first two sprints) and post-fatigue (last two sprints) were tested using paired t-tests. Performance decreased significantly (e.g. top speed decreased by 15.7±5.4%; Pmultiple-set repeated sprint series, both the total force production capability and the technical ability to apply force effectively against the ground are altered, the latter to a larger extent than the former. Copyright © 2011 Elsevier Ltd. All rights reserved.

The Force of Gardening: Investigating Children's Learning in a Food Garden

Science.gov (United States)

Green, Monica; Duhn, Iris

2015-01-01

School gardens are becoming increasingly recognised as important sites for learning and for bringing children into relationship with food. Despite the well-known educational and health benefits of gardening, children's interactions with the non-human entities and forces within garden surroundings are less understood and examined in the wider…

Scratch direction and threshold force in nanoscale scratching using atomic force microscopes

Energy Technology Data Exchange (ETDEWEB)

Tseng, Ampere A., E-mail: ampere.tseng@asu.edu [Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan (China); Kuo, Chung-Feng Jeffrey; Jou, Shyankay [Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan (China); Nishimura, Shinya; Shirakashi, Jun-ichi [Department of Electrical and Electronic Engineering, Tokyo University of Agriculture and Technology, Tokyo 184-8588 (Japan)

2011-09-01

The nanoscaled tip in an AFM (atomic force microscope) has become an effective scratching tool for material removing in nanofabrication. In this article, the characteristics of using a diamond-coated pyramidal tip to scratch Ni-Fe thin film surfaces was experimentally investigated with the focus on the evaluation of the influence of the scratch or scan direction on the final shape of the scratched geometry as well as the applied scratch force. Results indicated that both the scratched profile and the scratch force were greatly affected by the scratch direction. It has been found that, to minimize the formation of protuberances along the groove sides and to have a better control of the scratched geometry, the tip face should be perpendicular to the scratching direction, which is also known as orthogonal cutting condition. To demonstrate the present findings, three groove patterns have been scratched with the tip face perpendicular to the scratching direction and very little amount of protuberances was observed. The threshold scratch force was also predicted based on the Hertz contact theory. Without considering the surface friction and adhesive forces between the tip and substrate, the threshold force predicted was twice smaller than the measurement value. Finally, recommendations for technical improvement and research focuses are provided.

Scratch direction and threshold force in nanoscale scratching using atomic force microscopes

International Nuclear Information System (INIS)

Tseng, Ampere A.; Kuo, Chung-Feng Jeffrey; Jou, Shyankay; Nishimura, Shinya; Shirakashi, Jun-ichi

2011-01-01

The nanoscaled tip in an AFM (atomic force microscope) has become an effective scratching tool for material removing in nanofabrication. In this article, the characteristics of using a diamond-coated pyramidal tip to scratch Ni-Fe thin film surfaces was experimentally investigated with the focus on the evaluation of the influence of the scratch or scan direction on the final shape of the scratched geometry as well as the applied scratch force. Results indicated that both the scratched profile and the scratch force were greatly affected by the scratch direction. It has been found that, to minimize the formation of protuberances along the groove sides and to have a better control of the scratched geometry, the tip face should be perpendicular to the scratching direction, which is also known as orthogonal cutting condition. To demonstrate the present findings, three groove patterns have been scratched with the tip face perpendicular to the scratching direction and very little amount of protuberances was observed. The threshold scratch force was also predicted based on the Hertz contact theory. Without considering the surface friction and adhesive forces between the tip and substrate, the threshold force predicted was twice smaller than the measurement value. Finally, recommendations for technical improvement and research focuses are provided.

Trafficking in Persons: The U.S. and International Response

National Research Council Canada - National Science Library

Miko, Francis T

2006-01-01

Trafficking in people for prostitution and forced labor is one of the most prolific areas of international criminal activity and is of significant concern to the United States and the international community...

Investigating the Role of International Law in Controlling Communicable Diseases

Directory of Open Access Journals (Sweden)

Aliasghar Kheirkhah

2017-02-01

Full Text Available International law globally plays a key role in the surveillance and control of communicable diseases. Throughout the nineteenth century, international law played a dominant role in harmonizing the inconsistent national quarantine regulations of European nation states; facilitating the exchange of epidemiological information on infectious diseases; establishing international health organizations; and standardization of surveillance. Today, due to changed forms of infectious diseases and individuals' lifestyles as well as individuals' proximity caused by increased air travels, communicable diseases are in an international and cross-border form. In this regard, binding regulations and inconsistent rules adopted in international multilateral institutions like the World Health Organization, World Trade Organization, Food and Agriculture Organization can be of great use in surveillance and control of communicable diseases. With the globalization of public health, international law can be used as an essential tool in monitoring global health and reducing human vulnerability and mortality.

Towards an integrated model of international migration

Directory of Open Access Journals (Sweden)

Douglas S. MASSEY

2012-12-01

Full Text Available Demographers have yet to develop a suitable integrated model of international migration and consequently have been very poor at forecasting immigration. This paper outlines the basic elements of an integrated model and surveys recent history to suggest the key challenges to model construction. A comprehensive theory must explain the structural forces that create a supply of people prone to migrate internationally, the structural origins of labour demand in receiving countries, the motivations of those who respond to these forces by choosing to migrate internationally, the growth and structure of transnational networks that arise to support international movement, the behaviour states in response to immigrant flows, and the influence of state actions on the behaviour of migrants. Recent history suggests that a good model needs to respect the salience of markets, recognize the circularity of migrant flows, appreciate the power of feedback effects, and be alert unanticipated consequences of policy actions.

Medicolegal investigation of political killings in El Salvador.

Science.gov (United States)

Thomsen, J L; Gruschow, J; Stover, E

1989-06-17

An axiom of Thomas Hobbes states that "people are never more helpless than when the force meant to protect their rights turns against them." Hobbes' axiom holds true today, with Amnesty International reporting that hundreds of thousands have been murdered by their governments. This article examines the medicolegal aspects of an investigation into the deaths of two Salvadoran peasants who were reportedly tortured and executed by soldiers in February 1988. One of the authors, Thomsen, participated in the investigation as a court-ordered expert, and as a representative of the American Association for the Advancement of Science and of a Salvadoran legal aid organization. His necropsy findings are reported with observations and comments. The article concludes with suggestions for initiatives that might be undertaken by individual physicians and institutions to improve the quality and impartiality of medicolegal investigations into political killings.

32 CFR 632.4 - Deadly force.

Science.gov (United States)

2010-07-01

..., is substantially important to national security. (See paragraph (b) of this section.) (iii) Escape of... security or an essential national defense mission. (2) Substantially important to national security based... INVESTIGATIONS USE OF FORCE BY PERSONNEL ENGAGED IN LAW ENFORCEMENT AND SECURITY DUTIES § 632.4 Deadly force. (a...

A new magnetic spectrometer for the investigation of the internal conversion electron in capture reaction

International Nuclear Information System (INIS)

Suarez, A.A.

1978-01-01

Planning, development and manufacture of a new beta spectrometer for the investigation of the internal conversion electrons, from 0,02 to 10 MeV, emitted during the radioative capture process of the thermal neutrons. The resolution on the base of resolution curve is about 1,5 X 10 sup(-3) [pt

Impact of internal variability on projections of Sahel precipitation change

Science.gov (United States)

Monerie, Paul-Arthur; Sanchez-Gomez, Emilia; Pohl, Benjamin; Robson, Jon; Dong, Buwen

2017-11-01

The impact of the increase of greenhouse gases on Sahelian precipitation is very uncertain in both its spatial pattern and magnitude. In particular, the relative importance of internal variability versus external forcings depends on the time horizon considered in the climate projection. In this study we address the respective roles of the internal climate variability versus external forcings on Sahelian precipitation by using the data from the CESM Large Ensemble Project, which consists of a 40 member ensemble performed with the CESM1-CAM5 coupled model for the period 1920-2100. We show that CESM1-CAM5 is able to simulate the mean and interannual variability of Sahel precipitation, and is representative of a CMIP5 ensemble of simulations (i.e. it simulates the same pattern of precipitation change along with equivalent magnitude and seasonal cycle changes as the CMIP5 ensemble mean). However, CESM1-CAM5 underestimates the long-term decadal variability in Sahel precipitation. For short-term (2010-2049) and mid-term (2030-2069) projections the simulated internal variability component is able to obscure the projected impact of the external forcing. For long-term (2060-2099) projections external forcing induced change becomes stronger than simulated internal variability. Precipitation changes are found to be more robust over the central Sahel than over the western Sahel, where climate change effects struggle to emerge. Ten (thirty) members are needed to separate the 10 year averaged forced response from climate internal variability response in the western Sahel for a long-term (short-term) horizon. Over the central Sahel two members (ten members) are needed for a long-term (short-term) horizon.

Contact force structure and force chains in 3D sheared granular systems

Science.gov (United States)

Mair, Karen; Jettestuen, Espen; Abe, Steffen

2010-05-01

Faults often exhibit accumulations of granular debris, ground up to create a layer of rock flour or fault gouge separating the rigid fault walls. Numerical simulations and laboratory experiments of sheared granular materials, suggest that applied loads are preferentially transmitted across such systems by transient force networks that carry enhanced forces. The characterisation of such features is important since their nature and persistence almost certainly influence the macroscopic mechanical stability of these systems and potentially that of natural faults. 3D numerical simulations of granular shear are a valuable investigation tool since they allow us to track individual particle motions, contact forces and their evolution during applied shear, that are difficult to view directly in laboratory experiments or natural fault zones. In characterising contact force distributions, it is important to use global structure measures that allow meaningful comparisons of granular systems having e.g. different grain size distributions, as may be expected at different stages of a fault's evolution. We therefore use a series of simple measures to characterise the structure, such as distributions and correlations of contact forces that can be mapped onto a force network percolation problem as recently proposed by Ostojic and coworkers for 2D granular systems. This allows the use of measures from percolation theory to both define and characterise the force networks. We demonstrate the application of this method to 3D simulations of a sheared granular material. Importantly, we then compare our measure of the contact force structure with macroscopic frictional behaviour measured at the boundaries of our model to determine the influence of the force networks on macroscopic mechanical stability.

Processes of Internal and International Migration from Chitwan, Nepal.

Science.gov (United States)

Bohra, Pratikshya; Massey, Douglas S

2009-01-01

In this study we examine which factors predict internal and international migration from Chitwan, a flat valley located in the South-Central region of Nepal, seeking to measure the effect of theoretically specified variables such as human capital, social capital, physical capital, and neighborhood socioeconomic conditions while controlling for demographic variables. We use data from the Chitwan Valley Family Study (CVFS) to estimate a series of discrete time event history models of first and repeat migration to three competing destinations: other locations within Chitwan, other districts within Nepal, and places outside of Nepal. Results support hypotheses derived from neoclassical economics, the theory of new economics of migration, social capital theory, and cumulative causation theory. Our results underscore the need for a synthetic theoretical model that incorporates factors operating at the individual, household, and community levels. The use of multiple explanatory models yields a clearer picture of the forces driving internal and international migration from rural districts in developing nations such as Nepal.

Lift force fluctuations of magnetically levitated vehicles with an integrated synchronous linear motor and their significance for the technical security

Energy Technology Data Exchange (ETDEWEB)

Mnich, P; Huebner, K D

1980-07-15

In this paper the influence of the motor current on the magnetic force is investigated by an analytical method. With the integrated synchronous linear motor the reactions of the current sheet on the excitation field are depending on the pole angle and the amplitude of the current sheet. For an undisturbed operation - current sheet and induction wave in phase - the influence of the motor current on the magnetic force can be neglected. In case of a disturbed performance, i.e. when the pole angle is changing periodically, fluctuations of the magnetic force will be found. This effect has to be compensated by a reserve magnetic force in the levitation control. With the technical data for the new magnetic levitation pilots plants (International Traffic Fair 1979 at Hamburg and Transrapid - Pilot Plant Emsland) the stated relations are evaluated. Approximated relations for the levitation force are derived. For comparison, a finite-difference computer programme from the 'Institut fuer elektrische Maschinen, Antriebe und Bahnen, Technische Universitaet Braunschweig' is applied. The approximated relations developed in this paper are verified - with a sufficient precision - by the numerical calculations.

Atomic-force microscopy: a powerful, multipurpose technique for the investigation of materials

International Nuclear Information System (INIS)

Cousty, J.

2010-01-01

An atomic-force microscope (AFM) comprises a probe (a tip) mounted at the free extremity of a spring of known stiffness, a control system, and a scanning system, which moves the probe across the sample's surface. The interaction between probe and surface (forces, or force gradient) is kept equal to a set value, by continuously adjusting the separation distance, via a feedback loop. An AFM image thus corresponds to a constant-interaction contour, obtained by moving the tip along the surface. This contour matches, as a rule, the topography of the sample. The image obtained is then the topography of the surface. The contribution made by AFM to materials science is illustrated in 4 examples. The first example concerns the first observations of irradiation damage in an electrical insulator material, thus one not readily observable by means of conventional electron microscopes. The second illustration relates to monitoring the emergence of defects due to plastic deformation observed in metals. The third example serves as an illustration of the capability afforded by AFM, of ensuring the acquisition of two types of information. Using an AFM fitted with a special module, the electrical resistivity of the passive layer that covers the surface of stainless steels was measured, concurrently with the sample's topography. The final illustration concerns the 3-dimensional self-organization of molecules at the interface between a solid and a liquid. (A.C.)

Investigation on the Effect of a Pre-Center Drill Hole and Tool Material on Thrust Force, Surface Roughness, and Cylindricity in the Drilling of Al7075.

Science.gov (United States)

Ghasemi, Amir Hossein; Khorasani, Amir Mahyar; Gibson, Ian

2018-01-16

Drilling is one of the most useful metal cutting processes and is used in various applications, such as aerospace, electronics, and automotive. In traditional drilling methods, the thrust force, torque, tolerance, and tribology (surface roughness) are related to the cutting condition and tool geometry. In this paper, the effects of a pre-center drill hole, tool material, and drilling strategy (including continuous and non-continuous feed) on thrust force, surface roughness, and dimensional accuracy (cylindricity) have been investigated. The results show that using pre-center drill holes leads to a reduction of the engagement force and an improvement in the surface quality and cylindricity. Non-continuous drilling reduces the average thrust force and cylindricity value, and High Speed Steels HSS-Mo (high steel speed + 5-8% Mo) reduces the maximum quantity of cutting forces. Moreover, cylindricity is directly related to cutting temperature and is improved by using a non-continuous drilling strategy.

Investigation on the Effect of a Pre-Center Drill Hole and Tool Material on Thrust Force, Surface Roughness, and Cylindricity in the Drilling of Al7075

Directory of Open Access Journals (Sweden)

Amir Hossein Ghasemi

2018-01-01

Full Text Available Drilling is one of the most useful metal cutting processes and is used in various applications, such as aerospace, electronics, and automotive. In traditional drilling methods, the thrust force, torque, tolerance, and tribology (surface roughness are related to the cutting condition and tool geometry. In this paper, the effects of a pre-center drill hole, tool material, and drilling strategy (including continuous and non-continuous feed on thrust force, surface roughness, and dimensional accuracy (cylindricity have been investigated. The results show that using pre-center drill holes leads to a reduction of the engagement force and an improvement in the surface quality and cylindricity. Non-continuous drilling reduces the average thrust force and cylindricity value, and High Speed Steels HSS-Mo (high steel speed + 5–8% Mo reduces the maximum quantity of cutting forces. Moreover, cylindricity is directly related to cutting temperature and is improved by using a non-continuous drilling strategy.

Finite element modeling and experimentation of bone drilling forces

International Nuclear Information System (INIS)

Lughmani, W A; Bouazza-Marouf, K; Ashcroft, I

2013-01-01

Bone drilling is an essential part of many orthopaedic surgery procedures, including those for internal fixation and for attaching prosthetics. Estimation and control of bone drilling forces are critical to prevent drill breakthrough, excessive heat generation, and mechanical damage to the bone. This paper presents a 3D finite element (FE) model for prediction of thrust forces experienced during bone drilling. The model incorporates the dynamic characteristics involved in the process along with the accurate geometrical considerations. The average critical thrust forces and torques obtained using FE analysis, for set of machining parameters are found to be in good agreement with the experimental results

Cooperation Agreement. The text of the Cooperation Agreement between the International Atomic Energy Agency and the ITER International Fusion Energy Organization

International Nuclear Information System (INIS)

2009-01-01

The text of the Cooperation Agreement between the International Atomic Energy Agency and the ITER International Fusion Energy Organization is reproduced herein for the information of all Members. The Agreement entered into force on 13 October 2008 pursuant to Article 8

Cooperation Agreement. The Text of the Cooperation Agreement between the International Atomic Energy Agency and the ITER International Fusion Energy Organization

International Nuclear Information System (INIS)

2009-01-01

The text of the Cooperation Agreement between the International Atomic Energy Agency and the ITER International Fusion Energy Organization is reproduced herein for the information of all Members. The Agreement entered into force on 13 October 2008 pursuant to Article 8

International Investment Law and EU Law

DEFF Research Database (Denmark)

regional economic integration agreements, International Competition Law, International Investment Regulation, International Monetary Law, International Intellectual Property Protection and International Tax Law. In addition to the regular annual volumes, EYIEL Special Issues routinely address specific...... current topics in International Economic Law. The entry into force of the Lisbon Treaty entails sweeping changes with respect to foreign investment regulation. Most prominently, the Treaty on the Functioning of the European Union (TFEU) now contains in its Article 207 an explicit competence...... for the regulation of foreign direct investment as part of the Common Commercial Policy (CCP) chapter. With this new competence, the EU will become an important actor in the field of international investment politics and law. The new empowerment in the field of international investment law prompts a multitude...

International Inequalities: Algebraic Investigations into Health and Economic Development

Science.gov (United States)

Staats, Susan; Robertson, Douglas

2009-01-01

The Millennium Project is an international effort to improve the health, economic status, and environmental resources of the world's most vulnerable people. Using data associated with the Millennium Project, students use algebra to explore international development issues including poverty reduction and the relationship between health and economy.…

Investigation, sensitivity analysis, and multi-objective optimization of effective parameters on temperature and force in robotic drilling cortical bone.

Science.gov (United States)

Tahmasbi, Vahid; Ghoreishi, Majid; Zolfaghari, Mojtaba

2017-11-01

The bone drilling process is very prominent in orthopedic surgeries and in the repair of bone fractures. It is also very common in dentistry and bone sampling operations. Due to the complexity of bone and the sensitivity of the process, bone drilling is one of the most important and sensitive processes in biomedical engineering. Orthopedic surgeries can be improved using robotic systems and mechatronic tools. The most crucial problem during drilling is an unwanted increase in process temperature (higher than 47 °C), which causes thermal osteonecrosis or cell death and local burning of the bone tissue. Moreover, imposing higher forces to the bone may lead to breaking or cracking and consequently cause serious damage. In this study, a mathematical second-order linear regression model as a function of tool drilling speed, feed rate, tool diameter, and their effective interactions is introduced to predict temperature and force during the bone drilling process. This model can determine the maximum speed of surgery that remains within an acceptable temperature range. Moreover, for the first time, using designed experiments, the bone drilling process was modeled, and the drilling speed, feed rate, and tool diameter were optimized. Then, using response surface methodology and applying a multi-objective optimization, drilling force was minimized to sustain an acceptable temperature range without damaging the bone or the surrounding tissue. In addition, for the first time, Sobol statistical sensitivity analysis is used to ascertain the effect of process input parameters on process temperature and force. The results show that among all effective input parameters, tool rotational speed, feed rate, and tool diameter have the highest influence on process temperature and force, respectively. The behavior of each output parameters with variation in each input parameter is further investigated. Finally, a multi-objective optimization has been performed considering all the

Manipulating bubbles with secondary Bjerknes forces

Energy Technology Data Exchange (ETDEWEB)

Lanoy, Maxime [Institut Langevin, ESPCI ParisTech, CNRS (UMR 7587), PSL Research University, 1 rue Jussieu, 75005 Paris (France); Laboratoire Matière et Systèmes Complexes, Université Paris-Diderot, CNRS (UMR 7057), 10 rue Alice Domon et Léonie Duquet, 75013 Paris (France); Derec, Caroline; Leroy, Valentin [Laboratoire Matière et Systèmes Complexes, Université Paris-Diderot, CNRS (UMR 7057), 10 rue Alice Domon et Léonie Duquet, 75013 Paris (France); Tourin, Arnaud [Institut Langevin, ESPCI ParisTech, CNRS (UMR 7587), PSL Research University, 1 rue Jussieu, 75005 Paris (France)

2015-11-23

Gas bubbles in a sound field are submitted to a radiative force, known as the secondary Bjerknes force. We propose an original experimental setup that allows us to investigate in detail this force between two bubbles, as a function of the sonication frequency, as well as the bubbles radii and distance. We report the observation of both attractive and, more interestingly, repulsive Bjerknes force, when the two bubbles are driven in antiphase. Our experiments show the importance of taking multiple scatterings into account, which leads to a strong acoustic coupling of the bubbles when their radii are similar. Our setup demonstrates the accuracy of secondary Bjerknes forces for attracting or repealing a bubble, and could lead to new acoustic tools for noncontact manipulation in microfluidic devices.

Manipulating bubbles with secondary Bjerknes forces

International Nuclear Information System (INIS)

Lanoy, Maxime; Derec, Caroline; Leroy, Valentin; Tourin, Arnaud

2015-01-01

Gas bubbles in a sound field are submitted to a radiative force, known as the secondary Bjerknes force. We propose an original experimental setup that allows us to investigate in detail this force between two bubbles, as a function of the sonication frequency, as well as the bubbles radii and distance. We report the observation of both attractive and, more interestingly, repulsive Bjerknes force, when the two bubbles are driven in antiphase. Our experiments show the importance of taking multiple scatterings into account, which leads to a strong acoustic coupling of the bubbles when their radii are similar. Our setup demonstrates the accuracy of secondary Bjerknes forces for attracting or repealing a bubble, and could lead to new acoustic tools for noncontact manipulation in microfluidic devices

Reasons for medical evacuations of soldiers serving in International Security Assistance Force (ISAF) operation in Afghanistan.

Science.gov (United States)

Korzeniewski, Krzysztof; Gregulski, Robert

2014-01-01

The article presents the results of a research study into the reasons for medical evacuations of Polish military personnel taking part in the International Security Assistance Force (ISAF) operation in Afghanistan from 2007 to 2013. The authors have analysed medical records of 485 soldiers who were medically evacuated out of a combat zone in Afghanistan for battle injuries, non-battle injuries and diseases. Each medically evacuated Polish soldier was subjected to statistical analysis. The study population comprised 25,974 soldiers assigned to the Polish Military Contingent Afghanistan in the given period. From 2007 to 2013, 1.9% of the Polish military personnel (n = 485) participating in the ISAF operation in Afghanistan were evacuated for medical reasons before the scheduled termination of their contract. 40.6% of all medical evacuations were due to battle injuries, 32.4% due to non-battle injuries, and 27.0% due to diseases. ISAF is an example of a combat operation, in which battle injuries remain the leading health problem in mission participants. 3 of 4 Polish soldiers who were medically evacuated from Afghanistan were no longer fit for military service in the area of operations due to the traumas they had suffered.

FATF as international law institute

Directory of Open Access Journals (Sweden)

І. Б. Кудас

2013-10-01

Full Text Available The article is devoted to the history of creation, analysis of the legal bases of activity, forms of decision-making, control over their implementation, measures of impact on the national banking system «of the Task force on financial measures in the sphere of money laundering». In article also addressed the question of the modern status of international bodies in the system of subjects of international law.

19 CFR 207.8 - Questionnaires to have the force of subpoenas; subpoena enforcement.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Questionnaires to have the force of subpoenas; subpoena enforcement. 207.8 Section 207.8 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION... Questionnaires to have the force of subpoenas; subpoena enforcement. Any questionnaire issued by the Commission...

International Military Cooperation: From Concepts to Constructs

Science.gov (United States)

D'Orazio, Vito

2013-01-01

International cooperation on issues of security is a central concept in many theoretical debates in international relations. This dissertation is an attempt to lay the foundation for measuring military cooperation and understanding the forces brought forth through its expansion. The central notion is that the set of policies related to military…

Calculation of the force acting on a drop in a nonuniform flow of a current-supporting fluid

International Nuclear Information System (INIS)

Korovin, V.M.

1993-01-01

In the context of wide use of intense electric currents in various technological process, it is of practical interest to investigate the characteristics of the force action of electromagnetic fields on a variety of inclusions - solid particles, drops, gas bubbles - suspended in current-supporting fluids. In the available studies one treats the simplest case, in which the vortical component of the electromagnetic forces, generated by the interaction of the current with the internal magnetic field, is nonvanishing only in small vicinities near these inclusions, and therefore these electromagnetic forces do not generate global motion of the homogeneous current-supporting fluid. In practice, in most cases the vortical component of electromagnetic forces plays a substantial role in the whole operating region of the technological device, and the motion of the current-supporting fluid is created specifically by electromagnetic forces. In the case of a varying electromagnetic field the forces acting on particles are located in the conducting fluid, moving under the field action, were calculated by Korovim (Korovim, V. M., open-quotes The calculation of forces acting on suspended particles during the flow of a conducting fluid in a varying electromagnetic field,close quotes Magn. Gidrodin, No. 1 95-102 (1991)). In the present study the authors generalize the method suggested by Korovin for calculating forces applied to both drops and particles and gas bubbles suspended in the gradient flow of a fluid moving under the action of a constant electromagnetic field. 6 refs

International organization at war

DEFF Research Database (Denmark)

Schmitt, Olivier

2017-01-01

number of practices for their power advantage to take its full effect. The article also illustrates how looking at practices helps to explain policy decisions, such as NATO’s decision to engage in Afghanistan, the establishment of an International Security and Assistance Force (ISAF) strategy...... and the wording of policy papers. By studying a case of military diplomacy, the article contributes to the emerging scholarship aimed at bridging the gap between diplomatic studies and practice-based approaches to International Relations....

Experimental investigation on flow instability of forced circulation in a vertical mini-rectangular channel

International Nuclear Information System (INIS)

Yu Zhiting; Tan Sichao; Yuan Hongsheng; Zhuang Nailiang; Chen Hanying

2015-01-01

An experimental study was conducted to investigate the flow instability in a vertical mini-rectangular channel with distilled water as the working fluid. The rotational speed of the primary pump is gradually reduced to lower the inlet flow rate until the flow becomes unstable, while maintaining all other thermal parameters unchanged. Three types of instability, characterized by large amplitude oscillation, small amplitude oscillation and flow excursion, were identified from the experimental data. A stability map for the vertical mini-rectangular channel under forced circulation was established based on the Subcooling number and Phase Change number. The oscillation periods were correlated with the fluid transit time and the boiling delay time. A flow pattern map for vertical upward flow in a mini-rectangular channel was applied to confirm the flow patterns during the oscillation. The mechanisms of the three types of instability were obtained by considering several types of flow instabilities and comparing them with the oscillations observed in this work. (author)

Further investigation on "A multiplicative regularization for force reconstruction"

Science.gov (United States)

Aucejo, M.; De Smet, O.

2018-05-01

We have recently proposed a multiplicative regularization to reconstruct mechanical forces acting on a structure from vibration measurements. This method does not require any selection procedure for choosing the regularization parameter, since the amount of regularization is automatically adjusted throughout an iterative resolution process. The proposed iterative algorithm has been developed with performance and efficiency in mind, but it is actually a simplified version of a full iterative procedure not described in the original paper. The present paper aims at introducing the full resolution algorithm and comparing it with its simplified version in terms of computational efficiency and solution accuracy. In particular, it is shown that both algorithms lead to very similar identified solutions.

Cooperation Agreement. The Text of the Cooperation Agreement between the International Atomic Energy Agency and the ITER International Fusion Energy Organization

International Nuclear Information System (INIS)

2009-01-01

The text of the Cooperation Agreement between the International Atomic Energy Agency and the ITER International Fusion Energy Organization is reproduced herein for the information of all Members. The Agreement entered into force on 13 October 2008 pursuant to Article 8 [fr

Cooperation Agreement. The Text of the Cooperation Agreement between the International Atomic Energy Agency and the ITER International Fusion Energy Organization

International Nuclear Information System (INIS)

2009-01-01

The text of the Cooperation Agreement between the International Atomic Energy Agency and the ITER International Fusion Energy Organization is reproduced herein for the information of all Members. The Agreement entered into force on 13 October 2008 pursuant to Article 8 [es

Forced convection heat transfer in He II

International Nuclear Information System (INIS)

Kashani, A.

1986-01-01

An investigation of forced convection heat transfer in He II is conducted. The study includes both experimental and theoretical treatments of the problem. The experiment consists of a hydraulic pump and a copper flow tube, 3 mm in ID and 2m long. The system allows measurements of one-dimensional heat and mass transfer in He II. The heat transfer experiments are performed by applying heat at the midpoint along the length of the flow tube. Two modes of heat input are employed, i.e., step function heat input and square pulse heat input. The heat transfer results are discussed in terms of temperature distribution in the tube. The experimental temperature profiles are compared with numerical solutions of an analytical model developed from the He II energy equation. The bath temperature is set at three different values of 1.65, 1.80, and 1.95 K. The He II flow velocity is varied up to 90 cm/s. Pressure is monitored at each end of the flow tube, and the He II pressure drop is obtained for different flow velocities. Results indicate that He II heat transfer by forced convention is considerably higher than that by internal convection. The theoretical model is in close agreement with the experiment. He II pressure drop and friction factor are very similar to those of an ordinary fluid

Perceived Discrimination and International Students' Learning: An Empirical Investigation

Science.gov (United States)

Karuppan, Corinne M.; Barari, Mahua

2011-01-01

At a time when the number of internationally mobile students worldwide has been growing steadily, the US share of this market has been declining. Since, as it is often claimed, international students are the best ambassadors for their host countries, an effective recruitment strategy is to enhance their learning experience, with the expectation…

Unexpected properties of the centrifugal force

International Nuclear Information System (INIS)

Abramowicz, M.A.

1990-01-01

Contrary to what is stated in the Newtonian dynamics, rotation of a reference frame is not sufficient for the occurrence of the centrifugal force. Instead, the necessary and sufficient condition is a motion along a path different from that of a photon trajectory in space. This calls for a rather fundamental change in understanding of the very nature of the centrifugal force. It also has important practical physical consequences: in a strong gravitational field, where light trajectories are substantially curved, centrifugal force is much weaker than the Newtonian theory predicts. In addition, when there are closed (circular) photon trajectories in space, the centrifugal force may reverse its direction - it attracts towards the rotation axis!. The weakening of the centrifugal force in strong gravitational fields and the reversal of its direction in the neighbourhood of close photon trajectories in space fully and clearly explain puzzling examples of counter intuitive behaviour of dynamical effects of rotation found previously by several authors: e.g. reversal of the ellipticity behaviour of the relativistic Maclaurin spheroids (Chandrasekhar and Miller, 1974), reversal of the viscous torque action (Anderson and Lemos, 1988), or the fact that rotation increases internal pressure of a sufficiently compact star (Abramowicz and Wagoner, 1974). Weakening of the centrifugal force implies that rotating neutron stars are less oblate (and probably more stable) than the Newtonian theory predicts. This is important for the recently discussed question of how fast can pulsars spin. (author). 23 refs, 3 figs

Unexpected properties of the centrifugal force

International Nuclear Information System (INIS)

Abramowicz, M.A.

1990-01-01

Contrary to what is stated in the Newtonian dynamics, rotation of a reference frame is not sufficient for the occurrence of the centrifugal force. Instead, the necessary and sufficient condition is a motion along a path different from that of a photon trajectory in space. This calls for a rather fundamental change in understanding of the very nature of the centrifugal force. It also has important practical physical consequences: in a strong gravitational field, where light trajectories are substantially curved, centrifugal force is much weaker than the Newtonian theory predicts. In addition, when there are closed (circular) photon trajectories in space, the centrifugal force may reverse its direction - it attracts towards the rotation axis. The weakening of the centrifugal force in strong gravitational fields and the reversal of its direction in the neighborhood of close photon trajectories in space fully and clearly explain puzzling examples of counter intuitive behaviour of dynamical effects of rotation found previously by several authors: e.g. reversal of the ellipticity behaviour of the relativistic Maclaurin spheroids (Chandrasekhar and Miller, 1974), reversal of the viscous torque action (Anderson and Lemos, 1988) or the fact that rotation increases internal pressure of a sufficiently compact star (Abramowicz and Wagoner, 1974). Weakening of the centrifugal force implies that rotating neutron stars are less oblate (and probably more stable) than the Newtonian theory predicts. This is important for the recently discussed question of how fast can pulsars spins. (author). 31 refs, 3 figs

A standing pressure wave hypothesis of oscillating forces generated during a steam line break

International Nuclear Information System (INIS)

Tinoco, H.

2001-01-01

A rapid glance at the figure depicting the net forces acting on the reactor vessel and internals, as obtained through a CFD simulation of a BWR steam line break, reveals an amazing oscillating regularity of these forces which is in glaring contrast to the chaotic behaviour of the steam pressure field in the steam annulus. Assuming that the decompression process excites and maintains standing pressure waves in the annular cylindrical region constituted by the steam annulus, it is possible to reconstruct the net forces acting on the reactor vessel and internals through the contribution of almost only the first dispersive mode. If a Neumann boundary condition is assumed at the section connecting the steam annulus to the steam dome, the frequency predicted is approximately % 5.9 higher than that of the CFD simulations. However, this connecting section allows wave transmission, and a more appropriate boundary condition should be one of the Robin type. Therefore, this section is modelled as an absorbing wall, and the corresponding normal impedance is calculated using the CFD simulations. Week non-linear effects can also be observed in the calculated forces through the presence of the first subharmonic. By the methodology described above, an estimate of the forces acting on the reactor vessel and internals of unit 3 of Forsmark Nuclear Power Plant has been obtained. (author)

Prolonged internal displacement and common mental disorders in Sri Lanka: the COMRAID study.

Science.gov (United States)

Siriwardhana, Chesmal; Adikari, Anushka; Pannala, Gayani; Siribaddana, Sisira; Abas, Melanie; Sumathipala, Athula; Stewart, Robert

2013-01-01

Evidence is lacking on the mental health issues of internally displaced persons, particularly where displacement is prolonged. The COMRAID study was carried out in year 2011 as a comprehensive evaluation of Muslims in North-Western Sri Lanka who had been displaced since 1990 due to conflict, to investigate the prevalence and correlates of common mental disorders. A cross-sectional survey was carried out among a randomly selected sample of internally displaced people who had migrated within last 20 years or were born in displacement. The total sample consisted of 450 adults aged 18-65 years selected from 141 settlements. Common mental disorders (CMDs) and post-traumatic stress disorder (PTSD) prevalences were measured using the Patient Health Questionnaire and CIDI sub-scale respectively. The prevalence of any CMD was 18.8%, and prevalence for subtypes was as follows: somatoform disorder 14.0%, anxiety disorder 1.3%, major depression 5.1%, other depressive syndromes 7.3%. PTSD prevalence was 2.4%. The following factors were significantly associated with CMDs: unemployment (odds ratio 2.8, 95% confidence interval 1.6-4.9), widowed or divorced status (4.9, 2.3-10.1) and food insecurity (1.7, 1.0-2.9). This is the first study investigating the mental health impact of prolonged forced displacement in post-conflict Sri Lanka. Findings add new insight in to mental health issues faced by internally displaced persons in Sri Lanka and globally, highlighting the need to explore broader mental health issues of vulnerable populations affected by forced displacement.

Casimir-lifshitz force out of thermal equilibrium and asymptotic nonadditivity

NARCIS (Netherlands)

Antezza, Mauro; Pitaevskii, Lev P.; Stringari, Sandro; Svetovoy, Vitaly

2006-01-01

We investigate the force acting between two parallel plates held at different temperatures. The force reproduces, as limiting cases, the well-known Casimir-Lifshitz surface-surface force at thermal equilibrium and the surface-atom force out of thermal equilibrium recently derived by M. Antezza et

Protocol Additional to the agreement between the Republic of Armenia and the International Atomic Energy Agency for the application of safeguards in connection with the Treaty on the Non-Proliferation of Nuclear Weapons. Entry into force

International Nuclear Information System (INIS)

2004-01-01

Pursuant to Article 17 of the Protocol Additional to the Agreement between the Republic of Armenia and the International Atomic Energy Agency for the Application of Safeguards in Connection with the Treaty on the Non-Proliferation of Nuclear Weapons, the Additional Protocol entered into force on 28 June 2004, the date on which the Agency received from Armenia written notification that Armenia's statutory and/or constitutional requirements for entry into force had been met

Developing a programmatic approach to investigating and remediating many unrelated comprehensive environmental response, compensation, and liability act sites at Kelly Air Force Base

International Nuclear Information System (INIS)

Kamp, G.; Regan, P.; Ninesteel, R.; Martin, R.

1988-01-01

Kelly Air Force Base (AFB), which was founded in 1917, is involved in logistics and maintenance activities supporting the Air Logistics Command. In addition, Kelly AFB hosts over 50 tenant organizations representing the Air Force, Department of Defense, and other government agencies. Over the years waste disposal from this complex was conducted in a manner that led to the identification of over 30 sites to be included in the Installation Restoration Program (IRP) after the Phase 1 investigation. A methodology was needed to prioritize the Remedial Investigations and Feasibility Study (RI/FS) activities for the sites. A Strategy Plan was developed that involved reviewing and interpreting existing data, identifying data voids relative to site specific RI/FS activities, and developing methodology to prioritize activities. Sites were prioritized, and a comprehensive IRP planning document was developed. One data deficiency was revealed -- the lack of understanding of the Basewide hydrogeologic conditions necessary to establish an effective restoration program. A Hydrogeologic Investigation was initiated to provide this data. This data will allow better interpretation of the interaction of the sites, particularly those in close proximity, and improved planning of remediation activities

Ordered and isomorphic mapping of periodic structures in the parametrically forced logistic map

Energy Technology Data Exchange (ETDEWEB)

Maranhão, Dariel M., E-mail: dariel@ifsp.edu.br [Departamento de Ciências e Matemática, Instituto Federal de Educação, Ciência e Tecnologia de São Paulo, São Paulo (Brazil); Diretoria de Informática, Universidade Nove de Julho, São Paulo (Brazil)

2016-09-23

Highlights: • A direct description of the internal structure of a periodic window in terms of winding numbers is proposed. • Periodic structures in parameter spaces are mapped in a recurrent and isomorphic way. • Sequences of winding numbers show global and local organization of periodic domains. - Abstract: We investigate the periodic domains found in the parametrically forced logistic map, the classical logistic map when its control parameter changes dynamically. Phase diagrams in two-parameter spaces reveal intricate periodic structures composed of patterns of intersecting superstable orbits curves, defining the cell of a periodic window. Cells appear multifoliated and ordered, and they are isomorphically mapped when one changes the map parameters. Also, we identify the characteristics of simplest cell and apply them to other more complex, discussing how the topography on parameter space is affected. By use of the winding number as defined in periodically forced oscillators, we show that the hierarchical organization of the periodic domains is manifested in global and local scales.

A numerical investigation of laminar forced convection in a solar collector with non-circular duct

Directory of Open Access Journals (Sweden)

Teleszewski Tomasz Janusz

2017-01-01

Full Text Available This paper presents a two-dimensional numerical study to investigate laminar flow in a flat plate solar collector with non-circular duct (regular polygonal, elliptical, and Cassini oval shape featuring forced convection with constant axial wall heat flux and constant peripheral wall temperature (H1 condition. Applying the velocity profile obtained for the duct laminar flow, the energy equation was solved exactly for the constant wall heat flux using the Boundary Element Method (BEM. Poiseuille and Nusselt numbers were obtained for flows having a different number of geometrical factors. The results are presented and discussed in the form of tables and graphs. The area goodness factor and volume goodness factor are calculated. The predicted correlations for Poiseuille and Nusselt numbers may be a very useful resource for the design and optimization of solar collectors with non-circular ducts.

A numerical investigation of laminar forced convection in a solar collector with non-circular duct

Science.gov (United States)

Janusz Teleszewski, Tomasz

2017-11-01

This paper presents a two-dimensional numerical study to investigate laminar flow in a flat plate solar collector with non-circular duct (regular polygonal, elliptical, and Cassini oval shape) featuring forced convection with constant axial wall heat flux and constant peripheral wall temperature (H1 condition). Applying the velocity profile obtained for the duct laminar flow, the energy equation was solved exactly for the constant wall heat flux using the Boundary Element Method (BEM). Poiseuille and Nusselt numbers were obtained for flows having a different number of geometrical factors. The results are presented and discussed in the form of tables and graphs. The area goodness factor and volume goodness factor are calculated. The predicted correlations for Poiseuille and Nusselt numbers may be a very useful resource for the design and optimization of solar collectors with non-circular ducts.

Factors that influence ground reaction force profiles during counter movement jumping.

Science.gov (United States)

Eagles, Alexander N; Sayers, Mark G; Lovell, Dale I

2017-05-01

The purpose of this study was to examine how hip, knee and ankle kinetics and kinematics influence effective impulse production during countermovement jumps. Eighteen semi-professional soccer players (22.8±2.2 years) volunteered to participate in the study. Participants completed three maximal countermovement jumps on two force platforms (1000 Hz) that were linked to a nine camera infrared motion capture system (500 Hz). Kinetic and kinematic data revealed jumpers who fail to achieve uniform ground reaction force curves that result in optimal impulse production during their jump always display hip adduction and or hip internal rotation during the concentric phase of the countermovement jump. The variation of hip adduction and or internal rotation likely represents failed joint transition during the concentric phase of the countermovement jump and appears to account for a non-uniform force trace seen in these jumpers. The findings suggest rehabilitation and conditioning exercises for injury prevention and performance may benefit from targeting frontal and transverse plane movement.

Mechanism of force mode dip-pen nanolithography

Energy Technology Data Exchange (ETDEWEB)

Yang, Haijun, E-mail: yanghaijun@sinap.ac.cn, E-mail: swguo@sjtu.edu.cn, E-mail: wanghuabin@cigit.ac.cn [Key Laboratory for Thin Film and Microfabrication of the Ministry of Education, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240 (China); Interfacial Water Division and Key Laboratory of Interfacial Physics and Technology, Shanghai Institute of Applied Physics, CAS, Shanghai 201800 (China); Xie, Hui; Rong, Weibin; Sun, Lining [State Key Laboratory of Robotics and Systems, Harbin Institute of Technology, Harbin 150080 (China); Wu, Haixia; Guo, Shouwu, E-mail: yanghaijun@sinap.ac.cn, E-mail: swguo@sjtu.edu.cn, E-mail: wanghuabin@cigit.ac.cn [Key Laboratory for Thin Film and Microfabrication of the Ministry of Education, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240 (China); Wang, Huabin, E-mail: yanghaijun@sinap.ac.cn, E-mail: swguo@sjtu.edu.cn, E-mail: wanghuabin@cigit.ac.cn [Centre for Tetrahertz Research, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714 (China)

2014-05-07

In this work, the underlying mechanism of the force mode dip-pen nanolithography (FMDPN) is investigated in depth by analyzing force curves, tapping mode deflection signals, and “Z-scan” voltage variations during the FMDPN. The operation parameters including the relative “trigger threshold” and “surface delay” parameters are vital to control the loading force and dwell time for ink deposition during FMDPN. A model is also developed to simulate the interactions between the atomic force microscope tip and soft substrate during FMDPN, and verified by its good performance in fitting our experimental data.

CFD investigation of flow through internally riffled boiler tubes

DEFF Research Database (Denmark)

Rasmussen, Christian; Houbak, Niels; Sørensen, Jens Nørkær

1997-01-01

In this paper we show how to model the swirling flow in an internally riffled boiler tube. The flow field is visualized and the results are compared with measurements.......In this paper we show how to model the swirling flow in an internally riffled boiler tube. The flow field is visualized and the results are compared with measurements....

Recruiting for Foreign Language Skills Strategies for the Air Force

National Research Council Canada - National Science Library

Higgins, Maureen B

2008-01-01

.... The expeditionary Air Force (AF) mission demands Airmen with international insight, foreign language proficiency, and cultural knowledge to understand the specific regional context in which air and space power may be applied...

Sensitivity of Horn of Africa Rainfall to Regional Sea Surface Temperature Forcing

Directory of Open Access Journals (Sweden)

Zewdu T. Segele

2015-05-01

Full Text Available The Abdus Salam International Center for Theoretical Physics (ICTP version 4.4 Regional Climate Model (RegCM4 is used to investigate the rainfall response to cooler/warmer sea surface temperature anomaly (SSTA forcing in the Indian and Atlantic Oceans. The effect of SSTA forcing in a specific ocean basin is identified by ensemble, averaging 10 individual simulations in which a constant or linearly zonally varying SSTA is prescribed in individual basins while specifying the 1971–2000 monthly varying climatological sea surface temperature (SST across the remaining model domain. The nonlinear rainfall response to SSTA amplitude also is investigated by separately specifying +1K, +2K, and +4K SSTA forcing in the Atlantic and Indian Oceans. The simulation results show that warm SSTs over the entire Indian Ocean produce drier conditions across the larger Blue Nile catchment, whereas warming ≥ +2K generates large positive rainfall anomalies exceeding 10 mm·day−1 over drought prone regions of Northeastern Ethiopia. However, the June–September rainy season tends to be wetter (drier when the SST warming (cooling is limited to either the Northern or Southern Indian Ocean. Wet rainy seasons generally are characterized by deepening of the monsoon trough, east of 40°E, intensification of the Mascarene high, strengthening of the Somali low level jet and the tropical easterly jet, enhanced zonal and meridional vertically integrated moisture fluxes, and steeply vertically decreasing moist static energy. The opposite conditions hold for dry monsoon seasons.

Experimental investigation on TBAB clathrate hydrate slurry flows in a horizontal tube: Forced convective heat transfer behaviors

Energy Technology Data Exchange (ETDEWEB)

Wenji, Song [Guangzhou Institute of Energy Conversion, CAS, No. 2 Nengyuan Road, Tianhe District, Guangzhou 510640 (China); Key Laboratory of Renewable Energy and Gas Hydrate, CAS, No. 2 Nengyuan Road, Tianhe District, Guangzhou 510640 (China); Graduate School of Chinese Academy of Sciences, Beijing 100039 (China); Rui, Xiao; Chong, Huang; Shihui, He; Kaijun, Dong; Ziping, Feng [Guangzhou Institute of Energy Conversion, CAS, No. 2 Nengyuan Road, Tianhe District, Guangzhou 510640 (China); Key Laboratory of Renewable Energy and Gas Hydrate, CAS, No. 2 Nengyuan Road, Tianhe District, Guangzhou 510640 (China)

2009-11-15

Tetra-n-butyl-ammonium bromide (TBAB) clathrate hydrate slurry (CHS) is one kind of secondary refrigerants, which is promising to be applied into air-conditioning or latent-heat transportation systems as a thermal storage or cold carrying medium for energy saving. It is a solid-liquid two phase mixture which is easy to produce and has high latent heat and good fluidity. In this paper, the heat transfer characteristics of TBAB slurry were investigated in a horizontal stainless steel tube under different solid mass fractions and flow velocities with constant heat flux. One velocity region of weakened heat transfer was found. Moreover, TBAB CHS was treated as a kind of Bingham fluids, and the influences of the solid particles, flow velocity and types of flow on the forced convective heat transfer coefficients of TBAB CHS were investigated. At last, criterial correlations of Nusselt number for laminar and turbulent flows in the form of power function were summarized, and the error with experimental results was within {+-}20%. (author)

Shame and the Internalized Other

DEFF Research Database (Denmark)

Montes Sanchez, Alba

2015-01-01

In Shame and Necessity, Bernard Williams engages in a forceful vindication of the ethical significance of shame. In his view, shame is an extremely productive moral emotion because of the distinctive connection that it establishes between self, others and world, through a self-evaluation that is ......In Shame and Necessity, Bernard Williams engages in a forceful vindication of the ethical significance of shame. In his view, shame is an extremely productive moral emotion because of the distinctive connection that it establishes between self, others and world, through a self......-evaluation that is mediated by an internalized other. In this paper, I examine Williams’ conception of the internalized other and contrast it with other ways of conceiving the role of others in shame. I argue that, although Williams’ views contain many important insights, much is to be gained by conceiving the role of others...

On configurational forces for gradient-enhanced inelasticity

Science.gov (United States)

Floros, Dimosthenis; Larsson, Fredrik; Runesson, Kenneth

2018-04-01

In this paper we discuss how configurational forces can be computed in an efficient and robust manner when a constitutive continuum model of gradient-enhanced viscoplasticity is adopted, whereby a suitably tailored mixed variational formulation in terms of displacements and micro-stresses is used. It is demonstrated that such a formulation produces sufficient regularity to overcome numerical difficulties that are notorious for a local constitutive model. In particular, no nodal smoothing of the internal variable fields is required. Moreover, the pathological mesh sensitivity that has been reported in the literature for a standard local model is no longer present. Numerical results in terms of configurational forces are shown for (1) a smooth interface and (2) a discrete edge crack. The corresponding configurational forces are computed for different values of the intrinsic length parameter. It is concluded that the convergence of the computed configurational forces with mesh refinement depends strongly on this parameter value. Moreover, the convergence behavior for the limit situation of rate-independent plasticity is unaffected by the relaxation time parameter.

Investigation of high flux test module for the international fusion materials irradiation facilities (IFMIF)

International Nuclear Information System (INIS)

Miyashita, Makoto; Sugimoto, Masayoshi; Yutani, Toshiaki

2007-03-01

This report describes investigation on structure of a high neutron flux test module (HFTM) for the International Fusion Materials Irradiation Facilities (IFMIF). The HFTM is aimed for neutron irradiation of a specimen in a high neutron flux domain of the test cell for irradiation ground of IFMIF. We investigated the overall structure of the HFTM that was able to include specimens in a rig and thermocouple arrangement, an interface of control signal and support structure. Moreover, pressure and the amount of the bend in the module vessel (a rectangular section pressure vessel) were calculated. The module vessel did a rectangular section from limitation of a high neutron flux domain. Also, we investigated damage of thermocouples under neutron irradiation, which was a temperature sensor of irradiation materials temperature control demanded high precision. Based on these results, drawings on the HTFM structure. (author)

Performance investigation on a 4-bed adsorption desalination cycle with internal heat recovery scheme

KAUST Repository

Thu, Kyaw

2016-10-08

Multi-bed adsorption cycle with the internal heat recovery between the condenser and the evaporator is investigated for desalination application. A numerical model is developed for a 4-bed adsorption cycle implemented with the master-and-slave configuration and the aforementioned internal heat recovery scheme. The present model captures the reversed adsorption/desorption phenomena frequently associated with the unmatched switching periods. Mesoporous silica gel and water vapor emanated from the evaporation of the seawater are employed as the adsorbent and adsorbate pair. The experimental data and investigation for such configurations are reported for the first time at heat source temperatures from 50 °C to 70 °C. The numerical model is validated rigorously and the parametric study is conducted for the performance of the cycle at assorted operation conditions such as hot and cooling water inlet temperatures and the cycle times. The specific daily water production (SDWP) of the present cycle is found to be about 10 m/day per tonne of silica gel for the heat source temperature at 70 °C. Performance comparison is conducted for various types of adsorption desalination cycles. It is observed that the AD cycle with the current configuration provides superior performance whilst is operational at unprecedentedly low heat source temperature as low as 50 °C.

The effect of magnet size on the levitation force and attractive force of single-domain YBCO bulk superconductors

International Nuclear Information System (INIS)

Yang, W M; Chao, X X; Bian, X B; Liu, P; Feng, Y; Zhang, P X; Zhou, L

2003-01-01

The levitation forces between a single-domain YBCO bulk and several magnets of different sizes have been measured at 77 K to investigate the effect of the magnet size on the levitation force. It is found that the levitation force reaches a largest (peak) value when the size of the magnet approaches that of the superconductor when the other conditions are fixed. The absolute maximum attractive force (in the field-cooled state) increases with the increasing of the magnet size, and is saturated when the magnet size approaches that of the superconductor. The maximum attractive force in the field-cooled (FC) state is much higher than that of the maximum attractive force in the zero field-cooled (ZFC) state. The results indicate that the effects of magnetic field distribution on the levitation force have to be considered during the designing and manufacturing of superconducting devices

Joint Force Quarterly. Issue 56, 1st Quarter, January 2010

Science.gov (United States)

2010-01-01

tol/comment/ columnists /guest_contributors/ article6789136.ece>. 12 Greg Bruno, Afghanistan’s National Security Forces, Council on Foreign Relations...organized criminal syndicate and narco-trafficking organization in order to maintain its revenue flow. One such criminal activity the FARC engages...international system. It is not a member of the international community, except perhaps in the negative sense (much as organized crime syndicates are

The architecture of neutrophil extracellular traps investigated by atomic force microscopy

Science.gov (United States)

Pires, Ricardo H.; Felix, Stephan B.; Delcea, Mihaela

2016-07-01

Neutrophils are immune cells that engage in a suicidal pathway leading to the release of partially decondensed chromatin, or neutrophil extracellular traps (NETs). NETs behave as a double edged sword; they can bind to pathogens thereby ensnaring them and limiting their spread during infection; however, they may bind to host circulating materials and trigger thrombotic events, and are associated with autoimmune disorders. Despite the fundamental role of NETs as part of an immune system response, there is currently a very poor understanding of how their nanoscale properties are reflected in their macroscopic impact. In this work, using a combination of fluorescence and atomic force microscopy, we show that NETs appear as a branching filament network that results in a substantially organized porous structure with openings with 0.03 +/- 0.04 μm2 on average and thus in the size range of small pathogens. Topological profiles typically up to 3 +/- 1 nm in height are compatible with a ``beads on a string'' model of nucleosome chromatin. Typical branch lengths of 153 +/- 103 nm appearing as rigid rods and height profiles of naked DNA in NETs of 1.2 +/- 0.5 nm are indicative of extensive DNA supercoiling throughout NETs. The presence of DNA duplexes could also be inferred from force spectroscopy and the occurrence of force plateaus that ranged from ~65 pN to 300 pN. Proteolytic digestion of NETs resulted in widespread disassembly of the network structure and considerable loss of mechanical properties. Our results suggest that the underlying structure of NETs is considerably organized and that part of its protein content plays an important role in maintaining its mesh architecture. We anticipate that NETs may work as microscopic mechanical sieves with elastic properties that stem from their DNA-protein composition, which is able to segregate particles also as a result of their size. Such a behavior may explain their participation in capturing pathogens and their association

International Education Hubs: Collaboration for Competitiveness and Sustainability

Science.gov (United States)

Knight, Jane

2014-01-01

This chapter focuses on the development of education hubs, a recent phenomenon in international higher education. Three models of hubs are examined in relation to the forces, risks, and opportunities of globalization and how local and international collaborations are essential for both global competitiveness and sustainability.

Collector Efficiency in Downward-Type Internal-Recycle Solar Air Heaters with Attached Fins

Directory of Open Access Journals (Sweden)

Chii-Dong Ho

2013-10-01

Full Text Available The internal-recycle operation effect on collector efficiency in downward-type rectangular solar air heaters with attached fins is theoretically investigated. It is found that considerable collector efficiency is obtainable if the collector has attached fins and the operation is carried out with internal recycling. The recycling operation increases the fluid velocity to decrease the heat transfer resistance, compensating for the undesirable effect of decreasing the heat transfer driving force (temperature difference due to remixing. The attached fins provide an enlarged heat transfer area. The order of performance in a device of same size is: double pass with recycle and fins > double pass with recycle but without fins > single pass without recycle and fins.

Plasma igniter for internal-combustion engines

Science.gov (United States)

Breshears, R. R.; Fitzgerald, D. J.

1978-01-01

Hot ionized gas (plasma) ignites air/fuel mixture in internal combustion engines more effectively than spark. Electromagnetic forces propel plasma into combustion zone. Combustion rate is not limited by flame-front speed.

The states/BC oil spill task force - an international model for formulating and influencing public policy

International Nuclear Information System (INIS)

Neel, J.; Bones, J.; Dimmick, E.; Kent, L.J.T.; Dunstan, R.; Sutherland, B.

1993-01-01

The States/British Columbia Oil Spill Task Force was established in 1989 to enhance spill coordination among the West Coast states and British Columbia, and to address a number of issues that became apparent during the Nestucca barge and Exxon Valdez oil spills. Task Force members are the directors of the oil spill prevention and response agencies in Alaska, British Columbia, California, Oregon, and Washington. The Task Force has become a national model for facilitating cooperation and building consensus between coastal states and provinces and their federal governments. In October of 1990, the task force issued a report containing a comprehensive set of recommendations addressing oil spill prevention, preparedness, and response. The group had achieved remarkable consensus, and many of the report's recommendations have been included in recent legislation enacted by the member states. The success of the task force's approach to regional coordination has also reduced the need for a proposed Pacific Oceans Resources Interstate Compact, which has been proposed to expand the states' role in areas of regulation that are otherwise federally preempted. The task force has become an effective mechanism for developing vigorous, productive relationships between government agencies, industry, and the public in both the United States and Canada. It has created important linkages between state provincial antifederal regulatory activities; for example, by providing input to Coast Guard and EPA rulemaking that implemented the Oil Pollution Act of 1990. The task force is continuing to advance its goals of promoting public policy on oil spill prevention; cooperative management of major spills by government and industry; protection of the states provincial rights and their natural and economic resources; and inter-governmental consistency in regulations adopted for oil spill prevention, contingency planning, and resource damage assessment

Correlation functions for the fractional generalized Langevin equation in the presence of internal and external noise

International Nuclear Information System (INIS)

Sandev, Trifce; Metzler, Ralf; Tomovski, Živorad

2014-01-01

We study generalized fractional Langevin equations in the presence of a harmonic potential. General expressions for the mean velocity and particle displacement, the mean squared displacement, position and velocity correlation functions, as well as normalized displacement correlation function are derived. We report exact results for the cases of internal and external friction, that is, when the driving noise is either internal and thus the fluctuation-dissipation relation is fulfilled or when the noise is external. The asymptotic behavior of the generalized stochastic oscillator is investigated, and the case of high viscous damping (overdamped limit) is considered. Additional behaviors of the normalized displacement correlation functions different from those for the regular damped harmonic oscillator are observed. In addition, the cases of a constant external force and the force free case are obtained. The validity of the generalized Einstein relation for this process is discussed. The considered fractional generalized Langevin equation may be used to model anomalous diffusive processes including single file-type diffusion

Civil Air Patrol Proposed Agreements With the Air Force Are Intended to Address Identified Problems

National Research Council Canada - National Science Library

2000-01-01

The Air Force and Civil Air Patrol relationship is usually cooperative. The Air Force includes the Patrol in its internal budget process to determine what the Patrol needs and how much money will be available to support the Patrol...

Localization and force analysis at the single virus particle level using atomic force microscopy

International Nuclear Information System (INIS)

Liu, Chih-Hao; Horng, Jim-Tong; Chang, Jeng-Shian; Hsieh, Chung-Fan; Tseng, You-Chen; Lin, Shiming

2012-01-01

Highlights: ► Localization of single virus particle. ► Force measurements. ► Force mapping. -- Abstract: Atomic force microscopy (AFM) is a vital instrument in nanobiotechnology. In this study, we developed a method that enables AFM to simultaneously measure specific unbinding force and map the viral glycoprotein at the single virus particle level. The average diameter of virus particles from AFM images and the specificity between the viral surface antigen and antibody probe were integrated to design a three-stage method that sets the measuring area to a single virus particle before obtaining the force measurements, where the influenza virus was used as the object of measurements. Based on the purposed method and performed analysis, several findings can be derived from the results. The mean unbinding force of a single virus particle can be quantified, and no significant difference exists in this value among virus particles. Furthermore, the repeatability of the proposed method is demonstrated. The force mapping images reveal that the distributions of surface viral antigens recognized by antibody probe were dispersed on the whole surface of individual virus particles under the proposed method and experimental criteria; meanwhile, the binding probabilities are similar among particles. This approach can be easily applied to most AFM systems without specific components or configurations. These results help understand the force-based analysis at the single virus particle level, and therefore, can reinforce the capability of AFM to investigate a specific type of viral surface protein and its distributions.