77 FR 66082 - NASA International Space Station Advisory Committee; Meeting

Science.gov (United States)

2012-11-01

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 12-090] NASA International Space Station Advisory Committee; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of..., the National Aeronautics and Space Administration announces an open meeting of the NASA International...

Biophysics

CERN Document Server

Glaser, Roland

1999-01-01

The message of this book is that biophysics is the science of physical principles underlying the "phenomenon life" on all levels of organization. Rather than teaching "physics for biologists" or "physical methods applied to biology", it regards its subject as a defined discipline with its own network of ideas and approaches. The book starts by explaining molecular structures of biological systems, various kinds of atomic, molecular and ionic interactions, movements, energy transfer, self organization of supramolecular structures and dynamic properties of biological membranes. It then goes on to introduce the biological organism as a non-equilibrium system, before treating thermodynamic concepts of osmotic and electrolyte equilibria as well as currents and potential profiles. It continues with topics of environmental biophysics and such medical aspects as the influence of electromagnetic fields or radiation on living systems and the biophysics of hearing and noice protection. The book concludes with a discussi...

Methods in Modern Biophysics

CERN Document Server

Nölting, Bengt

2006-01-01

Incorporating recent dramatic advances, this textbook presents a fresh and timely introduction to modern biophysical methods. An array of new, faster and higher-power biophysical methods now enables scientists to examine the mysteries of life at a molecular level. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, proteomics, and protein folding and structure. Incorporating much information previously unavailable in tutorial form, Nölting employs worked examples and 267 illustrations to fully detail the techniques and their underlying mechanisms. Methods in Modern Biophysics is written for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in biophysics, biochemistry and related fields. Special features in the 2nd edition: • Illustrates the high-resolution methods for ultrashort-living protei...

Methods in Modern Biophysics

CERN Document Server

Nölting, Bengt

2010-01-01

Incorporating recent dramatic advances, this textbook presents a fresh and timely introduction to modern biophysical methods. An array of new, faster and higher-power biophysical methods now enables scientists to examine the mysteries of life at a molecular level. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, proteomics, and protein folding and structure. Incorporating much information previously unavailable in tutorial form, Nölting employs worked examples and about 270 illustrations to fully detail the techniques and their underlying mechanisms. Methods in Modern Biophysics is written for advanced undergraduate and graduate students, postdocs, researchers, lecturers, and professors in biophysics, biochemistry and related fields. Special features in the 3rd edition: Introduces rapid partial protein ladder sequencing - an important...

Biophysical Aspects of Radiation Quality. Second Panel Report

International Nuclear Information System (INIS)

1968-01-01

If a living system is exposed to ionizing radiation a sequence of events follows. It starts with the absorption and dissipation of radiation energy, and continues through various physico-chemical and biochemical reactions up to the final biological end point observed. One of the aims of research in quantitative radiation biology is to understand the mechanism of this sequence of actions and to explore the differences in quality of different kinds of radiations. Because of its complexity, progress in this work requires the combined efforts of physicists, biochemists, biologists and physicians. It should, however, be done in very close collaboration rather than in following isolated lines in any one direction. For this reason, and because of the growing importance of the field for almost all applications of ionizing radiations, it was felt desirable to bring together a group of scientists engaged in research on radiation quality who represented a wide range of interests. The first panel on Biophysical Aspects of Radiation Quality, convened by the International Atomic Energy Agency in Vienna and held from 29 March to 2 April 1965, proved to be a successful beginning, stimulating a useful exchange of ideas and information. By this meeting, and the resulting collection of papers, published in 1966 as No. 58 of the Agency's Technical Reports Series, the importance of research on radiation quality was highlighted and the field itself became more clearly defined. The Agency held a second Panel on the same subject in Vienna from 14 to 18 April 1967. This meeting was attended by 18 experts from 10 countries, and representatives from Euratom and WHO. The Czechoslovak Socialist Republic, France, India and Poland were represented for the first time. Fourteen papers were presented and discussed in some detail. It became evident that much progress had been made since the previous meeting in certain areas such as microdosimetry, the dependence of the oxygen effect on radiation

International Working Group on Fast Reactors Second Annual Meeting. Summary Report

International Nuclear Information System (INIS)

1969-01-01

The Agenda of the Meeting was as follows: Opening of the meeting. 2. Appraisal of the IWGFB's activity for the period from the first annual meeting of the Group. 3. Comments on national programmes on fast breeder reactors. 4. Presentation of general findings and conclusions of national and regional meetings on fast reactor problems held in represented countries and international organisations last year. 5. Comments on the programmes of international meetings on fast reactors to be held in 1969. 6. Consideration of a schedule for meetings on fast reactors in 1970. 7. Suggestions for the topics and location of specialists' meetings in 1969-1970. 8. Suggestions for reviews and studies in the field of fast reactors. 9. The time and place of the third annual meeting of the IWGFR. 10. Closing of the meeting

Course on Bioelectrochemistry which was the 11th International School of Biophysics

CERN Document Server

Blank, Martin

1983-01-01

This is the first course devoted to bioelectrochemistry held within the frame­ work of the International School of Biophysics. Although this branch of scientific research is already about two centuries old, as a truly independent one it has been in a stage of lively development since only a few decades ago and this is why a first course at the E. Majorana Center was devoted to it. Since bioelectrochemistry consists of many sub-fields, it is impossible to include, even superficially, all of them in a short course lasting just a week, and therefore the chapter of redox-reactions was chosen for this first course as being most general in character. But even restricting the course to redox-reactions, only a few subjects could be included and therefore the choice among them was made considering the most general guidelines that could serve as a basis for the further study of individual problems. In this way we hope to give a sound basis to the study of and to stimulate further interest in this branch of both biolog...

Internet and Audiology: A Review of the First International Meeting.

Science.gov (United States)

Andersson, Gerhard; Lunner, Thomas; Laplante-Lévesque, Ariane; Preminger, Jill E

2015-09-01

The purpose of this research forum article is to describe the impetus for holding the First International Meeting on Internet and Audiology (October 2014) and to introduce the special research forum that arose from the meeting. The rationale for the First International Meeting on Internet and Audiology is described. This is followed by a short description of the research sections and articles appearing in the special issue. Six articles consider the process of health care delivery over the Internet; this includes health care specific to hearing, tinnitus, and balance. Four articles discuss the development of effective Internet-based treatment programs. Six articles describe and evaluate Internet-based interventions specific to adult hearing aid users. The fledgling field of Internet and audiology is remarkably broad. The Second International Meeting on Internet and Audiology ocurred in September 2015.

English as a lingua franca used at international meetings

Directory of Open Access Journals (Sweden)

Barančicová Jana

2015-09-01

Full Text Available The paper deals with the use of English as a lingua franca. It concentrates on the environment of international meetings where English is used as a lingua franca. The aim of the research conducted through a survey of members of a NATO working group is to find out how native and non-native speakers feel about English used as a lingua franca during international meetings and how these two groups of speakers see each other in multinational interaction from the point of view of linguistics. The sections dealing with non-native speakers concentrate on the level of knowledge of English and on how native speakers cope with the English used during the meetings. The sections dealing with the views of English native speakers should establish the approach they take towards mistakes made by non-native speakers, whether native speakers should adjust the way they speak at international meetings and how they generally view the fact that their mother tongue is used all around the world.

Internet and Audiology: A Review of the Second International Meeting.

Science.gov (United States)

Laplante-Lévesque, Ariane; Lunner, Thomas; Andersson, Gerhard; Preminger, Jill E

2016-10-01

This article describes the Second International Meeting on Internet and Audiology, which took place at the Eriksholm Research Centre, Oticon A/S, Denmark September 24 to 25, 2015, and introduces the research forum arising from the meeting. The potential gains of the Internet within audiology are framed within the central role of quality connections among people, ideas, and objects. First, the meeting is summarized. Second, the 11 articles arising from the meeting and collected in this research forum are grouped into 2 themes: design and evaluation. Last, the benefits of interoperability and standardization are discussed. We look forward to the day when the Internet is an integral part of audiology, and we invite readers to attend future editions of the International Meeting on Internet and Audiology.

International Working Group on Fast Reactors Sixth Annual Meeting. Summary Report

International Nuclear Information System (INIS)

1973-01-01

The Agenda of the Meeting was as follows: 1. Review of IWGFR Activities - 1a. Approval of the minutes of the Fifth IWGFR Meeting. 1b. Report by Scientific Secretary regarding the activities of the Group. 2. Comments on National Programmes on Fast Breeder Reactors. 3. International Coordination of the Schedule for Major Fast Reactor Meetings and other major international meetings having a predominant fast reactor interest. 4. Consideration of Conferences on Fast Reactors. 4a. IAEA Symposium on Fuel and Fuel Elements for Fast Reactors, Brussels, Belgium 2-6 July 1973. 4b. International Symposium on Physics of Fast Reactors, Tokyo, Japan, 16 to 23 October 1973. 4c. International Conference on Fast Reactor Power Stations, London, UK, 11 to 14 March 1974 . 4d. Suggestions of the IWGFR members on other conferences. 5. Consideration of a Schedule for Specialists' Meetings in 1973-74. 6. Other Business - 6a. First-aid in Sodium Burns. 6b. Principles of Good Practice for Safe Operation of Sodium Circuits. 6c. Bibliography on Fast Reactors. 7. The Date and Place of the Seventh Annual Meeting of the IWGFR

International Meeting on Simulation in Healthcare 2007

National Research Council Canada - National Science Library

Gordon, James; Anderson, Beverlee

2007-01-01

1200 individuals attended the 2007 International Meeting on Simulation in Healthcare and had access to panels, keynotes and workshop sessions to further their knowledge of use of simulation in health...

New horizons in Biophysics

Science.gov (United States)

2011-01-01

This editorial celebrates the re-launch of PMC Biophysics previously published by PhysMath Central, in its new format as BMC Biophysics published by BioMed Central with an expanded scope and Editorial Board. BMC Biophysics will fill its own niche in the BMC series alongside complementary companion journals including BMC Bioinformatics, BMC Medical Physics, BMC Structural Biology and BMC Systems Biology. PMID:21595996

Fundamental Concepts in Biophysics Volume 1

CERN Document Server

Jue, Thomas

2009-01-01

HANDBOOK OF MODERN BIOPHYSICS Series Editor Thomas Jue, PhD Handbook of Modern Biophysics brings current biophysics topics into focus, so that biology, medical, engineering, mathematics, and physical-science students or researchers can learn fundamental concepts and the application of new techniques in addressing biomedical challenges. Chapters explicate the conceptual framework of the physics formalism and illustrate the biomedical applications. With the addition of problem sets, guides to further study, and references, the interested reader can continue to explore independently the ideas presented. Volume I: Fundamental Concepts in Biophysics Editor Thomas Jue, PhD In Fundamental Concepts in Biophysics, prominent professors have established a foundation for the study of biophysics related to the following topics: Mathematical Methods in Biophysics Quantum Mechanics Basic to Biophysical Methods Computational Modeling of Receptor–Ligand Binding and Cellular Signaling Processes Fluorescence Spectroscopy Elec...

Abstracts and papers of the 1996 International RERTR Meeting

International Nuclear Information System (INIS)

1996-10-01

The 1996 International Meeting on Reduced Enrichment for Research and Test Reactors (RERTR) was sponsored by the Korea Atomic Energy Research Institute and the International Atomic Energy Agency and was held in Seoul, Korea, on 6-10 October 1996. The abstracts and available papers that were presented at this meeting are provided. The most important subject dealt with was progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program. The major events, findings, and activities of 1996 are reviewed with the results which the RERTR Program has achieved by the end of 1995 in collaboration of the ANL and its many international partners

Abstracts and papers of the 1996 International RERTR Meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-10-01

The 1996 International Meeting on Reduced Enrichment for Research and Test Reactors (RERTR) was sponsored by the Korea Atomic Energy Research Institute and the International Atomic Energy Agency and was held in Seoul, Korea, on 6-10 October 1996. The abstracts and available papers that were presented at this meeting are provided. The most important subject dealt with was progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program. The major events, findings, and activities of 1996 are reviewed with the results which the RERTR Program has achieved by the end of 1995 in collaboration of the ANL and its many international partners.

Biophysical Evaluation of Food Decontamination Effects on Tissue and Bacteria

DEFF Research Database (Denmark)

Andersen, Ann Zahle; Duelund, Lars; Brewer, Jonathan

2011-01-01

Traditionally, the effects and efficiency of food surface decontamination processes, such as chlorine washing, radiation, or heating, have been evaluated by sensoric analysis and colony-forming unit (CFU) counts of surface swabs or carcass rinses. These methods suffice when determining probable...... consumer responses or meeting legislative contamination limits. However, in the often very costly, optimization process of a new method, more quantitative and unbiased results are invaluable. In this study, we employed a biophysical approach for the investigation of qualitative and quantitative changes...... that there are no contradictions between data obtained by either approach. However, the biophysical methods draw a much more nuanced picture of the effects and efficiency of the investigated decontamination method, revealing, e.g., an exponential dose/response relationship between SonoSteam® treatment time and changes in collagen...

Encyclopedia of biophysics

CERN Document Server

2013-01-01

The Encyclopedia of Biophysics is envisioned both as an easily accessible source of information and as an introductory guide to the scientific literature. It includes entries describing both Techniques and Systems.  In the Techniques entries, each of the wide range of methods which fall under the heading of Biophysics are explained in detail, together with the value and the limitations of the information each provides. Techniques covered range from diffraction (X-ray, electron and neutron) through a wide range of spectroscopic methods (X-ray, optical, EPR, NMR) to imaging (from electron microscopy to live cell imaging and MRI), as well as computational and simulation approaches. In the Systems entries, biophysical approaches to specific biological systems or problems – from protein and nucleic acid structure to membranes, ion channels and receptors – are described. These sections, which place emphasis on the integration of the different techniques, therefore provide an inroad into Biophysics from a biolo...

ICFA: Protvino meeting looks at trends in international collaboration

Energy Technology Data Exchange (ETDEWEB)

Anon.

1991-01-15

International collaboration is the lifeblood of Big Science, and in high energy physics the triennial 'Future Perspectives' meeting organized by the International Committee for Future Accelerators (ICFA) provides a valuable opportunity to reappraise trends in this collaboration. The latest meeting was held in October at Protvino, near Moscow, where the Institute for High Energy Physics is the scene of construction work for the 21-kilometre UNK proton rings and the projected home of a big new linear collider for electrons and positrons.

ICFA: Protvino meeting looks at trends in international collaboration

International Nuclear Information System (INIS)

Anon.

1991-01-01

International collaboration is the lifeblood of Big Science, and in high energy physics the triennial 'Future Perspectives' meeting organized by the International Committee for Future Accelerators (ICFA) provides a valuable opportunity to reappraise trends in this collaboration. The latest meeting was held in October at Protvino, near Moscow, where the Institute for High Energy Physics is the scene of construction work for the 21-kilometre UNK proton rings and the projected home of a big new linear collider for electrons and positrons

Contact expert group for international radwaste projects. Fourth meeting

International Nuclear Information System (INIS)

1997-06-01

The Contact Expert Group for International Radwaste Projects is the result of an IAEA seminar on ''International Co-operation on Nuclear Waste Management in the Russian Federation'', 15-17 May 1995, that was requested and sponsored by the Nordic countries. In two working groups at the Seminar, participants from the Russian Federation and 17 countries and international organizations co-operating with the Russian Federation in waste management projects recognized the need for setting up a contact group of experts to assist in co-ordinating their efforts. Such co-ordination would help avoid redundancy and duplication of effort, assure that priority needs were made known to the international community, and provide points of contact to facilitate co-operation. This report is a compilation of the 4. CEG meeting materials, both prepared by the CEG Secretariat and presented by meeting's participants. The materials discussed by the CEG and subsequently modified are presented in the finally approved version. As in the case of previous similar reports, the documentation presented was just compiled without any editing and thus should be considered only as ''working proceedings'' of the meeting

75 FR 32798 - Preparation for International Cooperation on Cosmetic Regulations; Public Meeting

Science.gov (United States)

2010-06-09

... cosmetics' industry trade associations. Currently, the ICCR members are Health Canada; the European... for International Cooperation on Cosmetic Regulations; Public Meeting AGENCY: Food and Drug... public meeting entitled ``International Cooperation on Cosmetic Regulations (ICCR)--Preparation for ICCR...

78 FR 20662 - Preparation for International Cooperation on Cosmetics Regulation; Public Meeting

Science.gov (United States)

2013-04-05

... authority members will enter into constructive dialogue with their relevant cosmetics industry trade...] Preparation for International Cooperation on Cosmetics Regulation; Public Meeting AGENCY: Food and Drug... public meeting entitled, ``International Cooperation on Cosmetics Regulation (ICCR)--Preparation for ICCR...

76 FR 18767 - Preparation for International Cooperation on Cosmetics Regulations; Public Meeting

Science.gov (United States)

2011-04-05

... cosmetics' industry trade associations. Currently, the ICCR members are Health Canada; the European...] Preparation for International Cooperation on Cosmetics Regulations; Public Meeting AGENCY: Food and Drug... announcing a public meeting entitled ``International Cooperation on Cosmetics Regulations (ICCR)--Preparation...

76 FR 58332 - Announcement of Meeting of the International Telecommunication Advisory Committee

Science.gov (United States)

2011-09-20

..., NW., Washington, DC 20520, to seek further advice from the telecommunications industry on (a) whether... DEPARTMENT OF STATE [Public Notice: 6869] Announcement of Meeting of the International Telecommunication Advisory Committee Summary: This notice announces a meeting of the International Telecommunication...

Proceedings of the Twentieth International Microgravity Measurements Group Meeting

Science.gov (United States)

DeLombard, Richard (Compiler)

2001-01-01

The International Microgravity Measurements Group annual meetings provide a forum for an exchange of information and ideas about various aspects of microgravity acceleration research in international microgravity research programs. These meetings are sponsored by the PI Microgravity Services (PIMS) project at the NASA Glenn Research Center. The twentieth MGMG meeting was held 7-9 August 2001 at the Hilton Garden Inn Hotel in Cleveland, Ohio. The 35 attendees represented NASA, other space agencies, universities, and commercial companies; eight of the attendees were international representatives from Canada, Germany, Italy, Japan, and Russia. Seventeen presentations were made on a variety of microgravity environment topics including the International Space Station (ISS), acceleration measurement and analysis results, science effects from microgravity accelerations, vibration isolation, free flyer satellites, ground testing, and microgravity outreach. Two working sessions were included in which a demonstration of ISS acceleration data processing and analyses were performed with audience participation. Contained within the minutes is the conference agenda which indicates each speaker, the title of their presentation, and the actual time of their presentation. The minutes also include the charts for each presentation which indicate the author's name(s) and affiliation. In some cases, a separate written report was submitted and has been included here.

Report on the IAEA Technical Meeting of the International Network of Nuclear Reaction Data Centres

International Nuclear Information System (INIS)

Forrest, R.; Dunaeva, S.; Otsuka, N.

2010-07-01

This report summarizes the IAEA Technical Meeting of the International Network of Nuclear Reaction Data Centres (biennial Data Centre Heads Meeting), held at the Japan Nuclear Reaction Data Centre, Hokkaido University, Sapporo, Japan, from 20 - 23 April 2010. The meeting was attended by 27 participants from 12 cooperating data centres of seven Member States and two International Organizations. The report contains a summary of the meeting, the conclusions and actions, the lists of working papers and presentations presented at the meeting. This report summarizes the IAEA Technical Meeting of the International Network of Nuclear Reaction Data Centres (biennial Data Centre Heads Meeting), held at the Japan Nuclear Reaction Data Centre, Hokkaido University, Sapporo, Japan, from 20 - 23 April 2010. The meeting was attended by 27 participants from 12 cooperating data centres of seven Member States and two International Organizations. The report contains a summary of the meeting, the conclusions and actions, the lists of working papers and presentations presented at the meeting. (author)

International Code Centres Network. Summary Report of the Technical Meeting

International Nuclear Information System (INIS)

Chung, H-K.

2011-01-01

Fifteen international experts on computational aspects of atomic, molecular and particle surface interaction data for fusion energy research participated in the 2nd technical meeting of the International Code Centres Network. Participants reported their research on data production and computational capabilities at their institutions. Experts in the field of plasma modeling of magnetic fusion research joined this meeting to present the data needs and bring the perspective of data users. The interaction and discussion among data producers and data users in this two-day meeting led to an agreement that the scope and function of Code Centres Network should be reformulated to serve the needs of fusion community in more effective way. (author)

Advanced Techniques in Biophysics

CERN Document Server

Arrondo, José Luis R

2006-01-01

Technical advancements are basic elements in our life. In biophysical studies, new applications and improvements in well-established techniques are being implemented every day. This book deals with advancements produced not only from a technical point of view, but also from new approaches that are being taken in the study of biophysical samples, such as nanotechniques or single-cell measurements. This book constitutes a privileged observatory for reviewing novel applications of biophysical techniques that can help the reader enter an area where the technology is progressing quickly and where a comprehensive explanation is not always to be found.

Biophysics of radiation action

International Nuclear Information System (INIS)

Dertinger, H.

1984-01-01

Understanding the cellular response to ionizing radiation is not only necessary to meet the requirements of radioprotection, but also for medical application of radiation in cancer treatment. In terms of radiobiology, cancer therapy means the selective inactivation of malignant cells without affecting the normal healthy tissue. However, for several physical and biological reasons, this ideal situation is normally not attained. The elaboration of biophysical parameters that could be used to improve the selective sterilization of tumor cells has become one of the main activities of cellular radiobiology during the last two decades. Progress in this field has been facilitated by the development of tissue culture techniques allowing to grow and analyze cells in a synthetic nutrient medium. This chapter describes the physical and biological factors which determine cellular radiosensitivity and which are important to know for better understanding the cellular radiation action, in particular with reference to cancer treatment

Biophysics and the Challenges of Emerging Threats

CERN Document Server

Puglisi, Joseph D

2009-01-01

This volume is a collection of articles from the proceedings of the International School of Structural Biology and Magnetic Resonance 8th Course: Biophysics and the Challenges of Emerging Threats. This NATO Advance Study Institute (ASI) was held in Erice at the Ettore Majorana Foundation and Centre for Scientific Culture on 19 through 30 June 2007. The ASI brought together a diverse group of experts who bridged the fields of virology and biology, biophysics, chemistry and physics. Prominent lecturers and students from around the world representant a total of 24 countries participated in the NATO ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU). The central hypothesis underlying this ASI was that interdisciplinary research, merging principles of physics, chemistry and biology, can drive new discovery in detecting and fighting bioterrorism agents, lead to cleaner environments, and help propel development in NATO partner countries. The ASI merged the relat...

Fifteenth annual meeting of the International Working Group on Fast Reactors. Summary report

International Nuclear Information System (INIS)

1982-09-01

The Fifteenth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous Annual Group Meeting, in Obninsk, USSR, Vienna from 30 March to 2 April 1982. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors

Sixteenth annual meeting of the International Working Group on Fast Reactors. Summary report

Energy Technology Data Exchange (ETDEWEB)

NONE

1983-10-01

The Sixteenth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous Annual Meeting Group, in Vienna from 12-15 April 1983. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors.

Fifteenth annual meeting of the International Working Group on Fast Reactors. Summary report

Energy Technology Data Exchange (ETDEWEB)

NONE

1982-09-01

The Fifteenth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous Annual Group Meeting, in Obninsk, USSR, Vienna from 30 March to 2 April 1982. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors.

Sixteenth annual meeting of the International Working Group on Fast Reactors. Summary report

International Nuclear Information System (INIS)

1983-10-01

The Sixteenth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous Annual Meeting Group, in Vienna from 12-15 April 1983. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors

76 FR 75599 - Advisory Committee on International Economic Policy; Notice of Meeting Cancellation

Science.gov (United States)

2011-12-02

... DEPARTMENT OF STATE [Public Notice: 7659] Advisory Committee on International Economic Policy; Notice of Meeting Cancellation The meeting of the Advisory Committee on International Economic Policy... Tiffany Enoch, Office of Economic Policy Analysis and Public Diplomacy, Bureau of Economic, and Business...

78 FR 49296 - NASA International Space Station Advisory Committee; Meeting

Science.gov (United States)

2013-08-13

.... Greg Mann, Office of International and Interagency Relations, (202) 358-5140, NASA Headquarters... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 13-091] NASA International Space Station... meeting. SUMMARY: In accordance with the Federal Advisory Committee Act, Public Law 92-463, as amended...

75 FR 51852 - NASA International Space Station Advisory Committee; Meeting

Science.gov (United States)

2010-08-23

.... Donald Miller, Office of International and Interagency Relations, (202) 358-1527, National Aeronautics... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-090)] NASA International Space Station... meeting. SUMMARY: In accordance with the Federal Advisory Committee Act, Public Law 92-463, as amended...

76 FR 33700 - Board for International Food and Agricultural Development; Notice of Meeting

Science.gov (United States)

2011-06-09

... Citizenship and Public Affairs, Syracuse University. Board members with continuing service include Elsa Murano... International Food and Agricultural Development; Notice of Meeting Pursuant to the Federal Advisory Committee Act, notice is hereby given of the public meeting of the Board for International Food and Agricultural...

Meeting of Commission of International Committee on Petrology of Coals

Energy Technology Data Exchange (ETDEWEB)

Timofeev, P P; Bogolyubova, L I

1982-03-01

In Urbana, Illinois from 18-20 May 1979 the XXXII session of the International Committee on Petrology met. Reports were made on standards for the study of bituminous and anthracite coals. Use of reflective capacity of vitrain to determine coalification of coals was discussed along with a proposition to establish numerical boundaries between brown, bituminous and anthracite coals. The re-editing of the International Dictionary on Petrology of Coals was agreed upon in view of new facts on microcomponents of coal and methods of studying them. The next meeting of the Commission took place at Ostrav, Czechoslovakia from 14-26 April 1980. At the plenary session, new officials were elected and agreement to re-edit the Dictionary on Petrology of Coals was confirmed. At the meeting of the Commission on Coal Petrography the question of the determination of components of coal by quantitative diagnosis, and results of determining components of vitrain by measuring its reflective capacity were reported on. At the meeting of the Committee on Applying Facts of Petrology in Geology, the classification of solid oil bitumen and organic substance of sediments was discussed. At the meeting of the Committee on the Application of the Petrology of Coals in Industry, attention was given to discussing basic parameters for the international classification of coals to be presented at the meeting of the Economic Commission of Europe in Geneva. In the final plenary session of the commission, results of discussions were summarized. The next session was to be held in France in 1981. (In Russian)

77 FR 61583 - International Energy Agency Meetings

Science.gov (United States)

2012-10-10

...) will meet on October 17 and 18, 2012, at the headquarters of the IEA in Paris, France in connection... the International Energy Agency (IEA) will be held at the headquarters of the IEA, 9, rue de la F... October 18. The purpose of this notice is to permit attendance by representatives of U.S. company members...

The biophysical link between climate, water, and vegetation in bioenergy agro-ecosystems

International Nuclear Information System (INIS)

Bagley, Justin E.; Davis, Sarah C.; Georgescu, Matei; Hussain, Mir Zaman; Miller, Jesse; Nesbitt, Stephen W.; VanLoocke, Andy; Bernacchi, Carl J.

2014-01-01

Land use change for bioenergy feedstocks is likely to intensify as energy demand rises simultaneously with increased pressure to minimize greenhouse gas emissions. Initial assessments of the impact of adopting bioenergy crops as a significant energy source have largely focused on the potential for bioenergy agroecosystems to provide global-scale climate regulating ecosystem services via biogeochemical processes. Such as those processes associated with carbon uptake, conversion, and storage that have the potential to reduce global greenhouse gas emissions (GHG). However, the expansion of bioenergy crops can also lead to direct biophysical impacts on climate through water regulating services. Perturbations of processes influencing terrestrial energy fluxes can result in impacts on climate and water across a spectrum of spatial and temporal scales. Here, we review the current state of knowledge about biophysical feedbacks between vegetation, water, and climate that would be affected by bioenergy-related land use change. The physical mechanisms involved in biophysical feedbacks are detailed, and interactions at leaf, field, regional, and global spatial scales are described. Locally, impacts on climate of biophysical changes associated with land use change for bioenergy crops can meet or exceed the biogeochemical changes in climate associated with rising GHG's, but these impacts have received far less attention. Realization of the importance of ecosystems in providing services that extend beyond biogeochemical GHG regulation and harvestable yields has led to significant debate regarding the viability of various feedstocks in many locations. The lack of data, and in some cases gaps in knowledge associated with biophysical and biochemical influences on land–atmosphere interactions, can lead to premature policy decisions. - Highlights: • The physical basis for biophysical impacts of expanding bioenergy agroecosystems on climate and water is described. • We

Biophysical pathology in cancer transformation

Czech Academy of Sciences Publication Activity Database

Pokorný, Jiří; Pokorný, Jan

S1, Nov (2013), s. 1-9 ISSN 2324-9110 R&D Projects: GA ČR(CZ) GAP102/11/0649 Institutional support: RVO:68378271 ; RVO:67985882 Keywords : cancer biophysics * Warburg effect * reverse Warburg effect * biological electrodynamics * coherent states Subject RIV: BO - Biophysics

Summary Report of the Technical Meeting on International Network of Nuclear Reaction Data Centres

International Nuclear Information System (INIS)

Otsuka, Naohiko

2013-07-01

This report summarizes the IAEA Technical Meeting on the International Network of Nuclear Reaction Data Centres, held at the IAEA Headquarters in Vienna, Austria from 23 to 25 April 2013. The meeting was attended by 24 participants representing 13 cooperative centres from 8 Member States and 2 International Organisations. A summary of the meeting is given in this report along with the conclusions and actions. (author)

A Multi-Sensor Approach to Enhance the Prediction of Mangrove Biophysical Characteristics in Chilika Lagoon and Bhitarkanika Wildlife Sanctuary, Odisha, India

Science.gov (United States)

Kumar, A.; Bledsoe, R.; Mishra, D. R.; Cameron, C.; Dahal, S.; Remillard, C.; Stone, A.; Stupp, P.

2017-12-01

Mangroves, one of the most productive ecosystems on Earth, play a major role in coastal ecosystem processes from mitigating erosion to acting as a barrier against tidal and storm surges associated with tropical cyclones. India has about 5 % of the world's mangrove vegetation, and over half of which is found along the east coast of the country. Chilika Lagoon and Bhitarkanika Wildlife Sanctuary are Ramsar sites of international wetland importance, situated in the state of Odisha along the east coast of India. Chilika Lagoon holds three small, but distinct mangrove patches, while Bhitarkanika Wildlife Sanctuary has several large, dense patches of mangroves. There is growing concern for the effective management and conservation of these mangrove forests. This study demonstrated the use of a suite of satellite data (Terra, Landsat, and Sentinel-1) for meeting the following objectives: 1. Derive a long-term spatio-temporal phenological maps of the biophysical parameters (chlorophyll, leaf area index, gross primary productivity, and evapotranspiration); 2. Analyze long-term spatio-temporal variability of physical and meteorological parameters; 3. Document decadal changes in mangroves area estimates starting from 1995 to 2017 using Landsat and radar data. The time series developed in this study revealed a phenological pattern for mangrove biophysical characteristics. Historical analysis of land cover maps indicated decrease in dense mangrove area and increase in open mangrove area and fragmentation. The results of this study will be used as an efficient biophysical mapping and monitoring protocol for mangrove forests in restoration decision-making.

XXIX International Meeting on Fundamental Physics, Sitges, Barcelona, Spain, 5-9 February, 2001

International Nuclear Information System (INIS)

Fonseca, V.; Dobado, A.

2001-01-01

The XXIX International Winter Meeting on Fundamental Physics took place in Sitges, Barcelona, Spain, from 5 to 9 February, 2001. The meeting was organized by the Universidad Complutense de Madrid (UCM) in collaboration with CIEMAT. It was supported by the Programa Nacional de Fisica de Altas Energias, by UCM and CIEMAT. As in previous editions, it brought together researchers working in experimental and theoretical Particle and Astroparticle Physics. More than seventy physicists from several countries participated in the Meeting. General talks, most recent results and time for physics discussions were considered in the program. In parallel to the development of the Meeting several other events took place. These events included a meeting to study the future of the Spanish Program of Advanced Studies in Theoretical High Energy Physics, an informal meeting to study the future for detection of high energy neutrino beams with underground detectors in the Canary Islands and another one concerning the PDGE /Proyecto Data Grid Espana). In addition we had the last day a special seminar in the honour of the 60th anniversary of Professor Yndurain. Francisco J. Yndurain played a leading role in the development of High Energy Physics in Spain and all over he was one of the founders of the International Meeting on Fundamental Physics in 1973 (in those days called International Winter Meeting on Fundamental Physics). The efficient assistance of M. Fatas in the organization of the conference is warmly appreciated. We thank R. Pascual for helping us to find the excellent hotel Calipolis where the meeting took place. We are deeply indebted to M. J. Josa and to the HEGRA people form the UCM for their valuable technical assistance along the entire process of preparing the Meeting. We also thank J. C. Gonzalez and M. Lopez for their effort in the preparation of these proceedings and finally to p. Seoane for the design of the poster, advertisements and the logo of the Meeting. Finally

Abstracts and papers of the 1997 International RERTR Meeting

International Nuclear Information System (INIS)

1997-10-01

The 1997 International Meeting on Reduced Enrichment for Research and Test Reactors (RERTR) was sponsored by the Argonne National Laboratory and was held in Jackson Hole, Wyoming, U.S.A. on 5-10 October 1997. The abstracts and available papers that were presented at this meeting are dealing with: National RERTR Programs; Fuel Development, Testing and Evaluation; Safety Tests and Evaluations; Core Conversion Studies; New LEU Reactors; Mo-99 Production From LEU Fission; Spent Fuel Management; Fuel Cycle issues

Summary Report on IAEA Technical Meeting on the International Network of Nuclear Reaction Data Centres

International Nuclear Information System (INIS)

Otsuka, Naohiko

2011-07-01

This report summarizes the IAEA Technical Meeting of the International Network of Nuclear Reaction Data Centres, held at the IAEA Headquarters in Vienna, Austria from 23 - 24 May 2011. The meeting was attended by 25 participants from 13 cooperating data centres of nine Member States and two International Organizations. The report contains a summary of the meeting, the conclusions and actions, the lists of working papers and presentations presented at the meeting. (author)

Summary Report of the Technical Meeting on International Network of Nuclear Reaction Data Centres

International Nuclear Information System (INIS)

Otsuka, Naohiko

2012-06-01

This report summarizes the IAEA Technical Meeting on the International Network of Nuclear Reaction Data Centres, held at the OECD Nuclear Energy Agency (NEA) in Issy-les-Moulineaux, France from 16 to 19 April 2012. The meeting was attended by twenty-three participants representing thirteen cooperative centres from eight Member States and two International Organisations. A summary of the meeting is given in this report along with the conclusions and actions. (author)

American Telemedicine Association: 18th Annual International Meeting & Tradeshow

Directory of Open Access Journals (Sweden)

Benjamin Forstag

2012-12-01

Full Text Available For 18 years, the American Telemedicine Association (ATA Annual International Meeting & Exposition has been the premier forum for professionals in the telemedicine, telehealth and mHealth space -- one of the fastest growing meetings in the country. ATA 2013 is on course to be the largest ATA meeting ever, with over 6,000 projected attendees.  The program will include 500 educational sessions and posters, highlighting the latest innovations, applications and research in telemedicine. The 2013 exhibit hall will feature nearly 300 of the leading vendors in remote healthcare technologies. With over 6000 projected attendees, from all around the world, there's no better place to meet and network with your peers and thought leaders in the field. Detailed program information--including courses, sessions and CME information--will be available January 2013 at:http://www.americantelemed.org.

Meeting Report: The Twelfth International Mouse Genome Conference

Energy Technology Data Exchange (ETDEWEB)

Manolakou, Katerina; Cross, Sally H.; Simpson, Eleanor H.; Jackson, Ian J.

1998-10-01

The annual International Mouse Genome Conference (IMGC) is where, scientifically speaking, classical mouse genetics meets the relative newcomer of genomics. The 12th meeting took place last October in the delightful Bavarian village of Garmisch-Partenkirchen, and we were greeted by the sight on the mountains of the first snowfall of the season. However the discussions left little time for exploration. Minds of participants in Garmisch were focused by a recent document produced by the NIH and by discussions within other funding agencies worldwide. If implemented, the proposals will further enhance the status of the mouse as the principal model for study of the function of the human genome.

Biophysical applications of satellite remote sensing

CERN Document Server

Hanes, Jonathan

2014-01-01

Including an introduction and historical overview of the field, this comprehensive synthesis of the major biophysical applications of satellite remote sensing includes in-depth discussion of satellite-sourced biophysical metrics such as leaf area index.

Mathematical biophysics

CERN Document Server

Rubin, Andrew

2014-01-01

This book presents concise descriptions and analysis of the classical and modern models used in mathematical biophysics. The authors ask the question "what new information can be provided by the models that cannot be obtained directly from experimental data?" Actively developing fields such as regulatory mechanisms in cells and subcellular systems and electron transport and energy transport in membranes are addressed together with more classical topics such as metabolic processes, nerve conduction and heart activity, chemical kinetics, population dynamics, and photosynthesis. The main approach is to describe biological processes using different mathematical approaches necessary to reveal characteristic features and properties of simulated systems. With the emergence of powerful mathematics software packages such as MAPLE, Mathematica, Mathcad, and MatLab, these methodologies are now accessible to a wide audience. Provides succinct but authoritative coverage of a broad array of biophysical topics and models Wr...

Historical and Critical Review on Biophysical Economics

Science.gov (United States)

Adigüzel, Yekbun

2016-07-01

Biophysical economics is initiated with the long history of the relation of economics with ecological basis and biophysical perspectives of the physiocrats. It inherently has social, economic, biological, environmental, natural, physical, and scientific grounds. Biological entities in economy like the resources, consumers, populations, and parts of production systems, etc. could all be dealt by biophysical economics. Considering this wide scope, current work is a “biophysical economics at a glance” rather than a comprehensive review of the full range of topics that may just be adequately covered in a book-length work. However, the sense of its wide range of applications is aimed to be provided to the reader in this work. Here, modern approaches and biophysical growth theory are presented after the long history and an overview of the concepts in biophysical economics. Examples of the recent studies are provided at the end with discussions. This review is also related to the work by Cleveland, “Biophysical Economics: From Physiocracy to Ecological Economics and Industrial Ecology” [C. J. Cleveland, in Advances in Bioeconomics and Sustainability: Essay in Honor of Nicholas Gerogescu-Roegen, eds. J. Gowdy and K. Mayumi (Edward Elgar Publishing, Cheltenham, England, 1999), pp. 125-154.]. Relevant parts include critics and comments on the presented concepts in a parallelized fashion with the Cleveland’s work.

Behaviour of core internals. Proceedings of the IAEA specialists meeting. Working document

International Nuclear Information System (INIS)

1998-01-01

This meeting was organized by the IAEA within the framework of its International Working Group on Life Management of Nuclear Power Plants. It was held in Rez near Prague on the 6-8 October 1998. The purpose of the meeting was to provide an international forum for discussion on recent results in research and utility experience and to provide recommendations for future developments in NPP life management programmes. 12 papers were presented during 3 sessions. Individual abstracts have been prepared for each of the papers

Report on the IAEA technical meeting of the International Network of Nuclear Reaction Data Centres

Energy Technology Data Exchange (ETDEWEB)

Schwerer, O; Dunaeva, S [International Atomic Energy Agency, Nuclear Data Section, Vienna (Austria); org, S Dunaeva@iaea [eds.

2007-11-15

An IAEA Technical Meeting of the International Network of Nuclear Reaction Data Centres was held at IAEA Headquarters, Vienna, Austria, from 8 to 10 October 2007. The meeting was attended by 19 participants from 11 cooperating data centres of six Member States and two international organizations. A summary of the meeting is given in this report, along with the conclusions, actions, and status reports of the participating data centres. (author)

Report on the IAEA technical meeting of the International Network of Nuclear Reaction Data Centres

International Nuclear Information System (INIS)

Schwerer, O.; Dunaeva, S.; S.Dunaeva@iaea.org

2007-11-01

An IAEA Technical Meeting of the International Network of Nuclear Reaction Data Centres was held at IAEA Headquarters, Vienna, Austria, from 8 to 10 October 2007. The meeting was attended by 19 participants from 11 cooperating data centres of six Member States and two international organizations. A summary of the meeting is given in this report, along with the conclusions, actions, and status reports of the participating data centres. (author)

75 FR 19671 - International Standards on the Transport of Dangerous Goods; Public Meeting

Science.gov (United States)

2010-04-15

... (UNSCOE TDG) to be held June 21-30, 2010 in Geneva, Switzerland. During this meeting, PHMSA is also... international agenda. Information Regarding The UNSCOE TDG Meeting: DATES: Wednesday, June 9, 2010; 9:30 a.m.-12..., 2013. Topics on the agenda for the UNSCOE TDG meeting include: [cir] Explosives and related matters...

77 FR 50516 - Fogarty International Center; Notice of Meetings

Science.gov (United States)

2012-08-21

... Board. The meeting will be open to the public as indicated below, with attendance limited to space... and the discussions could disclose confidential trade secrets or commercial property such as... Federal Domestic Assistance Program Nos. 93.106, Minority International Research Training Grant in the...

78 FR 50426 - Fogarty International Center; Notice of Meeting

Science.gov (United States)

2013-08-19

... meeting will be open to the public as indicated below, with attendance limited to space available... discussions could disclose confidential trade secrets or commercial property such as patentable materials, and... Assistance Program Nos. 93.106, Minority International Research Training Grant in the Biomedical and...

77 FR 1705 - Fogarty International Center; Notice of Meetings

Science.gov (United States)

2012-01-11

... meeting will be open to the public as indicated below, with attendance limited to space available... discussions could disclose confidential trade secrets or commercial property such as patentable materials, and... of Federal Domestic Assistance Program Nos. 93.106, Minority International Research Training Grant in...

The Third International Meeting on Genetic Disorders in the RAS/MAPK Pathway: Toward a Therapeutic Approach

OpenAIRE

Korf, Bruce; Ahmadian, Reza; Allanson, Judith; Aoki, Yoko; Bakker, Annette; Wright, Emma Burkitt; Denger, Brian; Elgersma, Ype; Gelb, Bruce D.; Gripp, Karen W.; Kerr, Bronwyn; Kontaridis, Maria; Lazaro, Conxi; Linardic, Corinne; Lozano, Reymundo

2015-01-01

"The Third International Meeting on Genetic Disorders in the RAS/MAPK Pathway: Towards a Therapeutic Approach" was held at the Renaissance Orlando at SeaWorld Hotel (August 2-4, 2013). Seventy-one physicians and scientists attended the meeting, and parallel meetings were held by patient advocacy groups (CFC International, Costello Syndrome Family Network, NF Network and Noonan Syndrome Foundation). Parent and patient advocates opened the meeting with a panel discussion to set the stage regard...

An ethnographic study: Becoming a physics expert in a biophysics research group

Science.gov (United States)

Rodriguez, Idaykis

Expertise in physics has been traditionally studied in cognitive science, where physics expertise is understood through the difference between novice and expert problem solving skills. The cognitive perspective of physics experts only create a partial model of physics expertise and does not take into account the development of physics experts in the natural context of research. This dissertation takes a social and cultural perspective of learning through apprenticeship to model the development of physics expertise of physics graduate students in a research group. I use a qualitative methodological approach of an ethnographic case study to observe and video record the common practices of graduate students in their biophysics weekly research group meetings. I recorded notes on observations and conduct interviews with all participants of the biophysics research group for a period of eight months. I apply the theoretical framework of Communities of Practice to distinguish the cultural norms of the group that cultivate physics expert practices. Results indicate that physics expertise is specific to a topic or subfield and it is established through effectively publishing research in the larger biophysics research community. The participant biophysics research group follows a learning trajectory for its students to contribute to research and learn to communicate their research in the larger biophysics community. In this learning trajectory students develop expert member competencies to learn to communicate their research and to learn the standards and trends of research in the larger research community. Findings from this dissertation expand the model of physics expertise beyond the cognitive realm and add the social and cultural nature of physics expertise development. This research also addresses ways to increase physics graduate student success towards their PhD. and decrease the 48% attrition rate of physics graduate students. Cultivating effective research

Summary Report of the Technical Meeting on International Network of Nuclear Reaction Data Centres

International Nuclear Information System (INIS)

Otuka, Naohiko; Herman, Michal

2016-07-01

This report summarizes the IAEA Technical Meeting on the International Network of Nuclear Reaction Data Centres held at the China Hall of Science and Technology in Beijing, China from 7 to 10 June 2016. The meeting was attended by 23 participants representing 13 cooperative Centres from 8 Member States (China, Hungary, India, Japan, Korea, Russia, Ukraine and USA) and 2 International Organisations (NEA, IAEA) as well as two participants from Kazakhstan. A summary of the meeting is given in this report along with the conclusions and actions. (author)

Twelfth annual meeting of the International Working Group on Fast Reactors. Summary report. Part I

Energy Technology Data Exchange (ETDEWEB)

NONE

1979-05-01

The Twelfth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous AGM,in Vienna from 27 to 30 March 1979. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors.

Twelfth annual meeting of the International Working Group on Fast Reactors. Summary report. Part I

International Nuclear Information System (INIS)

1979-05-01

The Twelfth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous AGM,in Vienna from 27 to 30 March 1979. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors

76 FR 48939 - Announcement of Meeting of the International Telecommunication Advisory Committee

Science.gov (United States)

2011-08-09

... Street, NW., Washington, DC 20520, to seek advice from the telecommunications industry on: (a) The consultation of International Telecommunication Union, Telecommunication Standardization Sector Study Group 15... Telecommunication Advisory Committee SUMMARY: This notice announces a meeting of the International Telecommunication...

proceedings of the 11. Annual meeting of the Federation of Societies on Experimental Biology

International Nuclear Information System (INIS)

1996-01-01

The proceedings of the 11. Annual meeting of the Federation of Societies on Experimental Biology contains 1850 abstracts, which include the following topics: neuroscience and behaviour; biophysics; pharmacology; comparative physiology; nervous regulation; endocrinology; nefrology; vascular biology; toxicity; molecular biophysics; radiobiology and others. Among these, 169 abstracts have been indexed separately for the INIS database

77 FR 52784 - U.S. Department of State Advisory Committee on Private International Law: Notice of Annual Meeting

Science.gov (United States)

2012-08-30

... Choice of Court Agreements; international contract law; developments in major PIL organizations... International Law: Notice of Annual Meeting The Department of State's Advisory Committee on Private International Law (ACPIL) will hold its annual meeting on developments in private international law on Thursday...

Abstracts and papers of the 2002 International RERTR Meeting

International Nuclear Information System (INIS)

2002-11-01

This 24th RERTR meeting has been organized in cooperation with the IAEA. It was attended by almost 200 participants coming from almost 30 different countries. Among them we have representatives from governmental and international organizations, private companies, reactor operators, fuel developers, regulators. The papers presented during following sessions: national and international RERTR programs, fuel development, manufacturing and qualification; fuel performance; HEU and LEU fuel cycle; LEU target development; licensing, safety and core assessment; reactor core conversion; acceptance program and spent fuel transportation; spent fuel management

Theoretical Molecular Biophysics

CERN Document Server

Scherer, Philipp

2010-01-01

"Theoretical Molecular Biophysics" is an advanced study book for students, shortly before or after completing undergraduate studies, in physics, chemistry or biology. It provides the tools for an understanding of elementary processes in biology, such as photosynthesis on a molecular level. A basic knowledge in mechanics, electrostatics, quantum theory and statistical physics is desirable. The reader will be exposed to basic concepts in modern biophysics such as entropic forces, phase separation, potentials of mean force, proton and electron transfer, heterogeneous reactions coherent and incoherent energy transfer as well as molecular motors. Basic concepts such as phase transitions of biopolymers, electrostatics, protonation equilibria, ion transport, radiationless transitions as well as energy- and electron transfer are discussed within the frame of simple models.

Biophysics an introduction

CERN Document Server

Cotteril, Rodney

2002-01-01

Biophysics: An Introduction, is a concise balanced introduction to this subject. Written in an accessible and readable style, the book takes a fresh, modern approach with the author successfully combining key concepts and theory with relevant applications and examples drawn from the field as a whole. Beginning with a brief introduction to the origins of biophysics, the book takes the reader through successive levels of complexity, from atoms to molecules, structures, systems and ultimately to the behaviour of organisms. The book also includes extensive coverage of biopolymers, biomembranes, biological energy, and nervous systems. The text not only explores basic ideas, but also discusses recent developments, such as protein folding, DNA/RNA conformations, molecular motors, optical tweezers and the biological origins of consciousness and intelligence.

76 FR 52016 - NASA International Space Station Advisory Committee and the Aerospace Safety Advisory Panel; Meeting

Science.gov (United States)

2011-08-19

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-074)] NASA International Space Station Advisory Committee and the Aerospace Safety Advisory Panel; Meeting AGENCY: National Aeronautics and Space... meeting of the NASA International Space Station Advisory Committee and the Aerospace Safety Advisory Panel...

76 FR 6171 - U.S. Department of State Advisory Committee on Private International Law (ACPIL): Public Meeting...

Science.gov (United States)

2011-02-03

... International Law (ACPIL): Public Meeting on Family Law The Department of State, Office of Legal Adviser, Office of Private International Law would like to give notice of a public meeting to discuss preparations for the upcoming Special Commission of the Hague Conference on Private International Law on the 1980...

Proceedings of the fifth PTCOG meeting and international workshop on biomedical accelerators

Energy Technology Data Exchange (ETDEWEB)

1987-04-01

This volume contains the proceeding and individual papers presented at the Fifth PTCOG meeting and International Workshop on Biomedical Accelerators. The meeting was divided into sessions on the biomedical aspects of therapy delivery, new biomedical accelerators, facilities, and beam localization and status report. Individual papers have been abstracted and indexed for the Energy Data Base.

Proceedings of the fifth PTCOG meeting and international workshop on biomedical accelerators

International Nuclear Information System (INIS)

1987-04-01

This volume contains the proceeding and individual papers presented at the Fifth PTCOG meeting and International Workshop on Biomedical Accelerators. The meeting was divided into sessions on the biomedical aspects of therapy delivery, new biomedical accelerators, facilities, and beam localization and status report. Individual papers have been abstracted and indexed for the Energy Data Base

Exploring the Educational Value of Clinical Vignettes from the Society of General Internal Medicine National Meeting in the Internal Medicine Clerkship

Science.gov (United States)

Wofford, James L; Singh, Sonal

2006-01-01

INTRODUCTION Whether the clinical vignettes presented at the Society of General Internal Medicine (SGIM) annual meeting could be of educational value to third year students in the Internal Medicine clerkship has not been studied. OBJECTIVE To explore the relevance and learning value of clinical vignettes from the SGIM national meeting in the Internal Medicine clerkship. SETTING Third year Ambulatory Internal Medicine clerkship at one academic medical center (academic year 2005 to 2006). METHODS Students were introduced to the clinical vignette and oriented to the database of clinical vignettes available through the SGIM annual meeting website. Students then reviewed 5 to 10 clinical vignettes using a worksheet, and rated the learning value of each vignette using a 5-point Likert scale (1 = least, 5 = greatest). A single investigator evaluated congruence of the vignette with the Clerkship Directors of Internal Medicine (CDIM)-SGIM curriculum to assess relevance. MAIN RESULTS A total of 42 students evaluated 371 clinical vignettes from the 2004 and 2005 meetings. The clinical vignettes were curriculum-congruent in 42.6% (n = 175), and clearly incongruent in 40.4% (n = 164). The mean rating for learning value was 3.8 (±1.0) (5 signifying greatest learning value). Curriculum-congruent vignettes had a higher mean learning value compared with curriculum-incongruent vignettes (4.0 vs 3.6, Student's t-test, P =.017). CONCLUSION The clinical vignettes presented at the national SGIM meeting offer clinical content that is relevant and of some educational value for third year clerkship students. Based on this pilot study, the educational value and strategies for their use in the clinical clerkships deserve further study. PMID:17026730

78 FR 70392 - Notice of Meeting of Advisory Committee on International Law

Science.gov (United States)

2013-11-25

... Law A meeting of the Department of State's Advisory Committee on International Law will take place on... Law School (Frederick Lawrence Student Conference Center), 2000 H Street NW., Washington, DC. Acting... Director, Advisory Committee on International Law, United States Department of State. [FR Doc. 2013-28232...

Clusters and Groups of Galaxies : International Meeting

CERN Document Server

Giuricin, G; Mezzetti, M

1984-01-01

The large-scale structure of the Universe and systems Clusters, and Groups of galaxies are topics like Superclusters, They fully justify the meeting on "Clusters of great interest. and Groups of Galaxies". The topics covered included the spatial distribution and the clustering of galaxies; the properties of Superclusters, Clusters and Groups of galaxies; radio and X-ray observations; the problem of unseen matter; theories concerning hierarchical clustering, pancakes, cluster and galaxy formation and evolution. The meeting was held at the International Center for Theoretical Physics in Trieste (Italy) from September 13 to September 16, 1983. It was attended by about 150 participants from 22 nations who presented 67 invited lectures (il) and contributed papers (cp), and 45 poster papers (pp). The Scientific Organizing Committee consisted of F. Bertola, P. Biermann, A. Cavaliere, N. Dallaporta, D. Gerba1, M. Hack, J . V . Peach, D. Sciama (Chairman), G. Setti, M. Tarenghi. We are particularly indebted to D. Scia...

International Discussion Meeting on High-Tc Superconductors

CERN Document Server

1988-01-01

In the past two years conferences on superconductivity have been characterized by the attendance of hundreds of scientists. Consequently, the organizers were forced to schedule numerous parallel sessions and poster presentations with an almost unsurveyable amount of information. It was, therefore, felt that a more informal get-together, providing ample time for a thourough discussion of some topics of current interest in high-temperature superconductivity, was timely and benefitial for leading scientists as well as for newcomers in the field. The present volume contains the majority of papers presented at the International Discussion Meeting on High-Tc Superconductors held at the Mauterndorf Castle in the Austrian Alps from February 7 to 11, 1988. Each subject was introduced in review form by a few invited speakers and then discussed together with the contributed poster presentations. These discussion sessions chaired by selected scientists turned out to be the highlights of the meeting, not only because all ...

Integrated Molecular and Cellular Biophysics

CERN Document Server

Raicu, Valerica

2008-01-01

This book integrates concepts and methods from physics, biology, biochemistry and physical chemistry into a standalone, unitary text of biophysics that aims to provide a quantitative description of structures and processes occurring in living matter. The book introduces graduate physics students and physicists interested in biophysics research to 'classical' as well as emerging areas of biophysics. The advanced undergraduate physics students and the life scientists are also invited to join in, by building on their knowledge of basic physics. Essential notions of biochemistry and biology are introduced, as necessary, throughout the book, while the reader's familiarity with basic knowledge of physics is assumed. Topics covered include interactions between biological molecules, physical chemistry of phospholipids association into bilayer membranes, DNA and protein structure and folding, passive and active electrical properties of the cell membrane, classical as well as fractal aspects of reaction kinetics and di...

77 FR 71028 - Notice of Meeting of Advisory Committee on International Law

Science.gov (United States)

2012-11-28

... Law A meeting of the Advisory Committee on International Law will take place on Friday December 14, from 9:30 a.m. to approximately 5:30 p.m., at the George Washington University Law School (Frederick... current international legal topics, including corporate social responsibility, principles of self-defense...

76 FR 72023 - Notice of Meeting of the Advisory Committee on International Law

Science.gov (United States)

2011-11-21

... International Law A meeting of the Advisory Committee on International Law will take place on Thursday, December 8, 2011, from 9:30 a.m. to approximately 5:30 p.m., at the George Washington University Law School...; federalism and international law; and the possibility of a new Restatement of Foreign Relations Law. Members...

75 FR 32532 - Notice of Meeting of the Advisory Committee on International Law

Science.gov (United States)

2010-06-08

... International Law A meeting of the Advisory Committee on International Law will take place on Monday, June 21, 2010, from 9:30 a.m. to approximately 5:30 p.m., at the George Washington University Law School... Criminal Court review conference and ad hoc international criminal tribunals; the law of war regarding...

IAEA International Database on Irradiated Nuclear Graphite Properties. Summary report of consultants' meeting. 12. meeting of the Technical Steering Committee

International Nuclear Information System (INIS)

Chung, H.K.; Wickham, A.J.

2010-02-01

The 12th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties was held on 12-13 November 2009 at the IAEA Headquarters, Vienna, Austria. All discussions, recommendations and actions of this Consultants' Meeting are recorded in this report. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database, and make recommendations for action over the next year. This report contains the status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

Biophysical influence of airborne carbon nanomaterials on natural pulmonary surfactant.

Science.gov (United States)

Valle, Russell P; Wu, Tony; Zuo, Yi Y

2015-05-26

Inhalation of nanoparticles (NP), including lightweight airborne carbonaceous nanomaterials (CNM), poses a direct and systemic health threat to those who handle them. Inhaled NP penetrate deep pulmonary structures in which they first interact with the pulmonary surfactant (PS) lining at the alveolar air-water interface. In spite of many research efforts, there is a gap of knowledge between in vitro biophysical study and in vivo inhalation toxicology since all existing biophysical models handle NP-PS interactions in the liquid phase. This technical limitation, inherent in current in vitro methodologies, makes it impossible to simulate how airborne NP deposit at the PS film and interact with it. Existing in vitro NP-PS studies using liquid-suspended particles have been shown to artificially inflate the no-observed adverse effect level of NP exposure when compared to in vivo inhalation studies and international occupational exposure limits (OELs). Here, we developed an in vitro methodology called the constrained drop surfactometer (CDS) to quantitatively study PS inhibition by airborne CNM. We show that airborne multiwalled carbon nanotubes and graphene nanoplatelets induce a concentration-dependent PS inhibition under physiologically relevant conditions. The CNM aerosol concentrations controlled in the CDS are comparable to those defined in international OELs. Development of the CDS has the potential to advance our understanding of how submicron airborne nanomaterials affect the PS lining of the lung.

La Rábida 2015 International Scientific Meeting on Nuclear Physics

CERN Document Server

Alonso, Clara; Andrés, María; Pérez-Bernal, Francisco

2016-01-01

This volume covers invited papers presented during the La Rábida 2015 International Scientific Meeting on Nuclear Physics, which can be considered heir of a well known series of triennial international summer schools on Nuclear Physics organized from 1982 till 2003 by the Basic Nuclear Physics group in the University of Sevilla. The La Rábida 2015 meeting offered to graduate students and young researchers a broad view of the field of Nuclear Physics. The first invited speaker presented the state-of-the-art of Relativistic Mean Field calculations. The second set of notes covers selected topics in gamma ray spectroscopy with exotic nuclei. The third speaker presented an introduction to the subject of severe accidents in nuclear power plants. In the forth set of notes, the author illustrated how to use laser spectroscopy to determine very important observables of atomic nuclei. The fifth speaker devoted its notes to explain several aspects of neutrino physics. Finally, the sixth speaker presented an overview o...

Developing a physics expert identity in a biophysics research group

Science.gov (United States)

Rodriguez, Idaykis; Goertzen, Renee Michelle; Brewe, Eric; Kramer, Laird H.

2015-06-01

We investigate the development of expert identities through the use of the sociocultural perspective of learning as participating in a community of practice. An ethnographic case study of biophysics graduate students focuses on the experiences the students have in their research group meetings. The analysis illustrates how the communities of practice-based identity constructs of competencies characterize student expert membership. A microanalysis of speech, sound, tones, and gestures in video data characterize students' social competencies in the physics community of practice. Results provide evidence that students at different stages of their individual projects have opportunities to develop social competencies such as mutual engagement, negotiability of the repertoire, and accountability to the enterprises as they interact with group members. The biophysics research group purposefully designed a learning trajectory including conducting research and writing it for publication in the larger community of practice as a pathway to expertise. The students of the research group learn to become socially competent as specific experts of their project topic and methodology, ensuring acceptance, agency, and membership in their community of practice. This work expands research on physics expertise beyond the cognitive realm and has implications for how to design graduate learning experiences to promote expert identity development.

Papers from the Fifth International Brain-Computer Interface Meeting

Science.gov (United States)

Huggins, Jane E.; Wolpaw, Jonathan R.

2014-06-01

Brain-computer interfaces (BCIs), also known as brain-machine interfaces (BMIs), translate brain activity into new outputs that replace, restore, enhance, supplement or improve natural brain outputs. BCI research and development has grown rapidly for the past two decades. It is beginning to provide useful communication and control capacities to people with severe neuromuscular disabilities; and it is expanding into new areas such as neurorehabilitation that may greatly increase its clinical impact. At the same time, significant challenges remain, particularly in regard to translating laboratory advances into clinical use. The papers in this special section report some of the work presented at the Fifth International BCI Meeting held on 3-7 June 2013 at the Asilomar Conference Center in Pacific Grove, California, USA. Like its predecessors over the past 15 years, this meeting was supported by the National Institutes of Health, the National Science Foundation, and a variety of other governmental and private sponsors [1]. This fifth meeting was organized and managed by a program committee of BCI researchers from throughout the world [2]. It retained the distinctive retreat-style format developed by the Wadsworth Center researchers who organized and managed the first four meetings. The 301 attendees came from 165 research groups in 29 countries; 37% were students or postdoctoral fellows. Of more than 200 extended abstracts submitted for peer review, 25 were selected for oral presentation [3], and 181 were presented as posters [4] and published in the open-access conference proceedings [5]. The meeting featured 19 highly interactive workshops [6] covering the broad spectrum of BCI research and development, as well as many demonstrations of BCI systems and associated technology. Like the first four meetings, this one included attendees and embraced topics from across the broad spectrum of disciplines essential to effective BCI research and development, including

Smoothing of, and parameter estimation from, noisy biophysical recordings.

Directory of Open Access Journals (Sweden)

Quentin J M Huys

2009-05-01

Full Text Available Biophysically detailed models of single cells are difficult to fit to real data. Recent advances in imaging techniques allow simultaneous access to various intracellular variables, and these data can be used to significantly facilitate the modelling task. These data, however, are noisy, and current approaches to building biophysically detailed models are not designed to deal with this. We extend previous techniques to take the noisy nature of the measurements into account. Sequential Monte Carlo ("particle filtering" methods, in combination with a detailed biophysical description of a cell, are used for principled, model-based smoothing of noisy recording data. We also provide an alternative formulation of smoothing where the neural nonlinearities are estimated in a non-parametric manner. Biophysically important parameters of detailed models (such as channel densities, intercompartmental conductances, input resistances, and observation noise are inferred automatically from noisy data via expectation-maximization. Overall, we find that model-based smoothing is a powerful, robust technique for smoothing of noisy biophysical data and for inference of biophysical parameters in the face of recording noise.

International Working Group on Fast Reactors Thirteenth Annual Meeting. Summary Report. Part II

International Nuclear Information System (INIS)

1980-10-01

The Thirteenth Annual Meeting of the IAEA International Working Group on Fast Reactors was held at the IAEA Headquarters, Vienna, Austria from 9 to 11 April 1980. The Summary Report (Part I) contains the Minutes of the Meeting. The Summary Report (Part II) contains the papers which review the national programme in the field of LMFBRs and other presentations at the Meeting. The Summary Report (Part III) contains the discussions on the review of the national programmes

International Working Group on Fast Reactors Thirteenth Annual Meeting. Summary Report. Part I

International Nuclear Information System (INIS)

1980-09-01

The Thirteenth Annual Meeting of the IAEA International Working Group on Fast Reactors was held at the IAEA Headquarters, Vienna, Austria from 9 to 11 April 1980. The Summary Report (Part I) contains the Minutes of the Meeting. The Summary Report (Part II) contains the papers which review the national programme in the field of LMFBRs and other presentations at the Meeting. The Summary Report (Part III) contains the discussions on the review of the national programmes

International Code Centres Network. Summary Report of the 3rd Biennial Technical Meeting

International Nuclear Information System (INIS)

Chung, Hyun-Kyung

2013-07-01

This report summarizes the proceedings of the third Technical Meeting of the International Code Centres Network held on 6-8 May in 2013. Ten experts from seven member states and four IAEA staff members attended the three-day meeting held at the IAEA Headquarters in Vienna to discuss issues on uncertainty estimates of theoretical atomic and molecular data. The report includes discussions on data issues, meeting conclusions and recommendations for the IAEA Atomic and Molecular Data Unit. (author)

International Working Group on Past Reactors Thirteenth Annual Meeting. Summary Report. Part III

International Nuclear Information System (INIS)

1981-04-01

The Thirteenth Annual Meeting of the IAEA International Working Group on Fast Reactors was held at the IAEA Headquarters, Vienna, Austria from 9 to 11 April 1980. The Summary Report (Part I) contains the Minutes of the Meeting. The Summary Report (Part II) contains the papers which review the national programme in the field of LMFBRs and other presentations at the Meeting. The Summary Report (Part III) contains the discussions on the review of the national programmes

76 FR 77584 - U.S. Department of State Advisory Committee on Private International Law (ACPIL): Public Meeting...

Science.gov (United States)

2011-12-13

... International Law (ACPIL): Public Meeting on Electronic Commerce The Department of State, Office of Legal... electronic transferable records. Working Group IV (international electronic commerce) of the United Nations... electronic transferable records. A report from that meeting, once it is published, should be available at...

Structure and biophysics

CERN Document Server

Puglisi, Joseph D

2007-01-01

This volume is a collection of articles from the proceedings of the ISSBMR 7th Course: Structure and Biophysics - New Technologies for Current Challenges in Biology and Beyond. This NATO Advanced Institute (ASI) was held in Erice at the Ettore Majorana Foundation and Centre for Scientific Culture on 22 June through 3 July 2005. The ASI brought together a diverse group of experts in the fields of Structural Biology, Biophysics and Physics. Prominent lecturers, from seven different countries, and students from around the world participated in the NATO ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU). Advances in nuclear magnetic resonance spectroscopy (NMR) and x-ray crystallography have allowed the three-dimensional structures of many biological macromolecules and their complexes, including the ribosome and RNA polymerase to be solved. Fundamental principles of NMR spectroscopy and dynamics, x-ray crystallography, computation and experimental dynamics we...

Meeting report of the first conference of the International Placenta Stem Cell Society (IPLASS)

Science.gov (United States)

Parolini, O.; Alviano, F.; Betz, A.G.; Bianchi, D.W.; Götherström, C.; Manuelpillai, U.; Mellor, A.L.; Ofir, R.; Ponsaerts, P.; Scherjon, S.A.; Weiss, M.L.; Wolbank, S.; Wood, K.J.; Borlongan, C.V.

2012-01-01

The International Placenta Stem Cell Society (IPLASS) was founded in June 2010. Its goal is to serve as a network for advancing research and clinical applications of stem/progenitor cells isolated from human term placental tissues, including the amnio-chorionic fetal membranes and Wharton's jelly. The commitment of the Society to champion placenta as a stem cell source was realized with the inaugural meeting of IPLASS held in Brescia, Italy, in October 2010. Officially designated as an EMBO-endorsed scientific activity, international experts in the field gathered for a 3-day meeting, which commenced with “Meet with the experts” sessions, IPLASS member and board meetings, and welcome remarks by Dr. Ornella Parolini, President of IPLASS. The evening's highlight was a keynote plenary lecture by Dr. Diana Bianchi. The subsequent scientific program consisted of morning and afternoon oral and poster presentations, followed by social events. Both provided many opportunities for intellectual exchange among the 120 multi-national participants. This allowed a methodical and deliberate evaluation of the status of placental cells in research in regenerative and reparative medicine. The meeting concluded with Dr. Parolini summarizing the meeting's highlights. This further prepared the fertile ground on which to build the promising potential of placental cell research. The second IPLASS meeting will take place in September 2012 in Vienna, Austria. This meeting report summarizes the thought-provoking lectures delivered at the first meeting of IPLASS. PMID:21575989

77 FR 19646 - International Whaling Commission; 64th Annual Meeting; Nominations

Science.gov (United States)

2012-04-02

... Commissioner representing the positions of non-governmental organizations. Generally, only one non-governmental... the U.S. IWC Commissioner representing the positions of non-governmental organizations. Generally... International Whaling Commission; 64th Annual Meeting; Nominations AGENCY: National Marine Fisheries Service...

Exploring the biophysical option space for feeding the world without deforestation.

Science.gov (United States)

Erb, Karl-Heinz; Lauk, Christian; Kastner, Thomas; Mayer, Andreas; Theurl, Michaela C; Haberl, Helmut

2016-04-19

Safeguarding the world's remaining forests is a high-priority goal. We assess the biophysical option space for feeding the world in 2050 in a hypothetical zero-deforestation world. We systematically combine realistic assumptions on future yields, agricultural areas, livestock feed and human diets. For each scenario, we determine whether the supply of crop products meets the demand and whether the grazing intensity stays within plausible limits. We find that many options exist to meet the global food supply in 2050 without deforestation, even at low crop-yield levels. Within the option space, individual scenarios differ greatly in terms of biomass harvest, cropland demand and grazing intensity, depending primarily on the quantitative and qualitative aspects of human diets. Grazing constraints strongly limit the option space. Without the option to encroach into natural or semi-natural land, trade volumes will rise in scenarios with globally converging diets, thereby decreasing the food self-sufficiency of many developing regions.

Biophysical properties and functional significance of stem water storage tissues in Neotropical savanna trees.

Science.gov (United States)

F.G. Scholz; S.J. Bucci; G. Goldstein; F.C. Meinzer; A.C. Franco; F. Miralles-Wilhelm

2007-01-01

Biophysical characteristics of sapwood and outer parenchyma water storage compartments were studied in stems of eight dominant Brazilian Cerrado tree species to assess the impact of differences in tissue capacitance on whole-plant water relations. Both the sapwood and outer parenchyma tissues played an important role in regulation of internal water deficits of Cerrado...

Meeting report: GSC M5 roundtable at the 13th International Society for Microbial Ecology meeting in Seattle, WA, USA August 22-27, 2010

Science.gov (United States)

Gilbert, Jack A.; Meyer, Folker; Knight, Rob; Field, Dawn; Kyrpides, Nikos; Yilmaz, Pelin; Wooley, John

2010-01-01

This report summarizes the proceedings of the Metagenomics, Metadata, Metaanalysis, Models and Metainfrastructure (M5) Roundtable at the 13th International Society for Microbial Ecology Meeting in Seattle, WA, USA August 22-27, 2010. The Genomic Standards Consortium (GSC) hosted this meeting as a community engagement exercise to describe the GSC to the microbial ecology community during this important international meeting. The roundtable included five talks given by members of the GSC, and was followed by audience participation in the form of a roundtable discussion. This report summarizes this event. Further information on the GSC and its range of activities can be found at http://www.gensc.org. PMID:21304725

Meeting report: GSC M5 roundtable at the 13th International Society for Microbial Ecology meeting in Seattle, WA, USA August 22-27, 2010.

Science.gov (United States)

Gilbert, Jack A; Meyer, Folker; Knight, Rob; Field, Dawn; Kyrpides, Nikos; Yilmaz, Pelin; Wooley, John

2010-12-15

This report summarizes the proceedings of the Metagenomics, Metadata, Metaanalysis, Models and Metainfrastructure (M5) Roundtable at the 13th International Society for Microbial Ecology Meeting in Seattle, WA, USA August 22-27, 2010. The Genomic Standards Consortium (GSC) hosted this meeting as a community engagement exercise to describe the GSC to the microbial ecology community during this important international meeting. The roundtable included five talks given by members of the GSC, and was followed by audience participation in the form of a roundtable discussion. This report summarizes this event. Further information on the GSC and its range of activities can be found at http://www.gensc.org.

Proceedings of fifth international topical meeting on nuclear thermal hydraulics, operations and safety

International Nuclear Information System (INIS)

1997-01-01

The fifth international topical meeting on nuclear thermohydraulics, operations and safety was convened in Beijing in April 14-18, 1997. The topical meeting was sponsored by the Chinese Nuclear Society and cosponsored by American Nuclear Society, Atomic Energy Society of Japan, American Society of Mechanical Engineers, Canada Nuclear Society, Korean Nuclear Society, Mexican Nuclear Society, Nuclear Society of Slovenia and Spanish Nuclear Society. There were 262 articles were published in the meeting. They are related nuclear power thermohydraulics, operations and safety

76 FR 34209 - International Whaling Commission; 63rd Annual Meeting; Nominations

Science.gov (United States)

2011-06-13

... Commissioner representing the positions of non-governmental organizations. Generally, only one non-governmental... recommendations to the U.S. IWC Commissioner representing the positions of non-governmental organizations... International Whaling Commission; 63rd Annual Meeting; Nominations AGENCY: National Marine Fisheries Service...

Biophysics: for HTS hit validation, chemical lead optimization, and beyond.

Science.gov (United States)

Genick, Christine C; Wright, S Kirk

2017-09-01

There are many challenges to the drug discovery process, including the complexity of the target, its interactions, and how these factors play a role in causing the disease. Traditionally, biophysics has been used for hit validation and chemical lead optimization. With its increased throughput and sensitivity, biophysics is now being applied earlier in this process to empower target characterization and hit finding. Areas covered: In this article, the authors provide an overview of how biophysics can be utilized to assess the quality of the reagents used in screening assays, to validate potential tool compounds, to test the integrity of screening assays, and to create follow-up strategies for compound characterization. They also briefly discuss the utilization of different biophysical methods in hit validation to help avoid the resource consuming pitfalls caused by the lack of hit overlap between biophysical methods. Expert opinion: The use of biophysics early on in the drug discovery process has proven crucial to identifying and characterizing targets of complex nature. It also has enabled the identification and classification of small molecules which interact in an allosteric or covalent manner with the target. By applying biophysics in this manner and at the early stages of this process, the chances of finding chemical leads with novel mechanisms of action are increased. In the future, focused screens with biophysics as a primary readout will become increasingly common.

76 FR 33399 - Advisory Committee on International Economic Policy; Notice of Open Meeting

Science.gov (United States)

2011-06-08

... concerning issues and challenges in international economic policy. The meeting will focus on issues relating to the advent of cloud computing as a new business model in international trade, the implications of... (Omnibus Diplomatic Security and Antiterrorism Act of 1986), as amended; Public Law 107-56 (USA Patriot Act...

Summary report of consultants meeting on IAEA International Database on Irradiated Nuclear Graphite Properties. 11. meeting of the Technical Steering Committee

International Nuclear Information System (INIS)

Humbert, D.; Wickham, A.J.

2009-05-01

The 11th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties was held on 25-26 March 2009 at the IAEA Headquarters, Vienna, Austria. All discussions, recommendations and actions of this Consultants' Meeting are recorded in this report. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database, and make recommendations for action over the next year. This report contains the status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

Summary report of consultants' meeting - IAEA International Database on Irradiated Nuclear Graphite Properties. 8th meeting of the Technical Steering Committee

International Nuclear Information System (INIS)

Humbert, D.; Wickham, A.J.

2006-05-01

The '8th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties' was held on 15-16 March 2006 at the IAEA Headquarters, Vienna, Austria. All discussions, recommendations and actions of this Consultants' Meeting are recorded in this report. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database and make recommendations for actions for the next year. This report contains the current status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

Fourteenth Annual Meeting of the International Working Group on Past Reactors. Summary Report. Part I

International Nuclear Information System (INIS)

1981-11-01

The Fourteenth Annual Meeting of the IAEA-IWGFR was held in accordance with the recommendations of the previous Annual Group Meeting, at the Vienna International Centre, Vienna from 31 March to 3 April 1981. All Member States of the group were represented at the meeting: France, the Federal Republic of Germany, India, Italy, Japan, the Union of Soviet Socialist Republics, the United Kingdom and the United States of America. The meeting was also attended by representatives from the Commission of European Communities, the Nuclear Energy Agency of the Organisation for Economic Co-operation and Development, the International Atomic Energy Agency and observers from Switzerland. The Agenda of the Meeting was as follows: 1. Review of IWGFR activities; 2. Consideration of future method of operation of the IWGFR; 3. Consideration of Conferences on Fast Reactors; 4. Consideration of the major recommendations of some of the IWGFR specialists' meetings for which the support of the IWGFR is requested; 5. Consideration of a schedule for specialists' meetings in 1981-1982; 6. Presentations and discussions on national programmes on fast breeder reactors.; 7. Recommendation of the IWGFR regarding a request of Switzerland concerning participation in the IWGFR; 8. The date and place of the Fifteenth Annual Meeting of the IWGFR

Radiation dosimetry and radiation biophysics

International Nuclear Information System (INIS)

Anon.

1981-01-01

Radiation dosimetry and radiation biophysics are two closely integrated programs whose joint purpose is to explore the connections between the primary physical events produced by radiation and their biological consequences in cellular systems. The radiation dosimetry program includes the theoretical description of primary events and their connection with the observable biological effects. This program also is concerned with the design and measurement of physical parameters used in theory or to support biological experiments. The radiation biophysics program tests and uses the theoretical developments for experimental design, and provides information for further theoretical development through experiments on cellular systems

Radiation dosimetry and radiation biophysics

International Nuclear Information System (INIS)

Anon.

1979-01-01

Radiation dosimetry and radiation biophysics are two closely integrated programs whose joint purpose is to explore the connections between the primary physical events produced by radiation and their biological consequences in cellular systems. The radiation dosimetry program includes the theoretical description of primary events and their connection with the observable biological effects. This program also is concerned with design and measurement of those physical parameters used in the theory or to support biological experiments. The radiation biophysics program tests and makes use of the theoretical developments for experimental design. Also, this program provides information for further theoretical development through experiments on cellular systems

Meeting Report of the Fifth International Cancer Epigenetics Conference in Beijing, China, October 2016.

Science.gov (United States)

Gao, Dan; Herman, James G; Cui, Hengmi; Jen, Jin; Fuks, Francois; Brock, Malcolm V; Ushijima, Toshikazu; Croce, Carlo; Akiyama, Yoshimitsu; Guo, Mingzhou

2017-07-01

Fifth International Cancer Epigenetics Conference, Beijing, China, 21-23 October 2016 This meeting reported many new findings in the field of cancer epigenetics, including basic science, translational and clinical studies. In this report, we summarize some of the main advancements and prospects in cancer epigenetics presented at this meeting.

International Meeting: Excited QCD 2014

CERN Document Server

Giacosa, Francesco; Malek, Magdalena; Marinkovic, Marina; Parganlija, Denis

2014-01-01

Excited QCD 2014 will take place on the beautiful Bjelasnica mountain located in the vicinity of the Bosnian capital Sarajevo. Bjelasnica was a venue of the XIV Winter Olympic Games and it is situated only 30 kilometers from Sarajevo International Airport. The workshop program will start on February 2 and finish on February 8, 2014, with scientific lectures taking place from February 3 to 7. Workshop participants will be accomodated in Hotel Marsal, only couple of minutes by foot from the Olympic ski slopes. ABOUT THE WORKSHOP This edition is the sixth in a series of workshops that were previously organised in Poland, Slovakia, France and Portugal. Following the succesful meeting in 2013, the Workshop is returning to Sarajevo Olympic mountains in 2014, exactly thirty years after the Games. The workshop covers diverse aspects of QCD: (i) QCD at low energies: excited hadrons, glueballs, multiquarks. (ii) QCD at high temperatures and large densities: heavy-ion collisions, jets, diffraction, hadronisation, quark-...

Abstracts and Papers of the 2003 International RERTR Meeting

International Nuclear Information System (INIS)

2003-10-01

The papers presented at the 25th International Meeting on Reduced Enrichment for Research and Test Reactors (RERTR) were classified according to the following subjects: National programs covering shipment of HEU to countries of origin and national RERTR programs; Molybdenum 99 production by using LEU fuel; Development and fabrication of new type of LEU fuel elements; Reactor core conversion analysis; Safety, spent fuel and regulatory issues; spent fuel storage and management

The Biophysics Microgravity Initiative

Science.gov (United States)

Gorti, S.

2016-01-01

Biophysical microgravity research on the International Space Station using biological materials has been ongoing for several decades. The well-documented substantive effects of long duration microgravity include the facilitation of the assembly of biological macromolecules into large structures, e.g., formation of large protein crystals under micro-gravity. NASA is invested not only in understanding the possible physical mechanisms of crystal growth, but also promoting two flight investigations to determine the influence of µ-gravity on protein crystal quality. In addition to crystal growth, flight investigations to determine the effects of shear on nucleation and subsequent formation of complex structures (e.g., crystals, fibrils, etc.) are also supported. It is now considered that long duration microgravity research aboard the ISS could also make possible the formation of large complex biological and biomimetic materials. Investigations of various materials undergoing complex structure formation in microgravity will not only strengthen NASA science programs, but may also provide invaluable insight towards the construction of large complex tissues, organs, or biomimetic materials on Earth.

Abstracts of the 10. Annual meeting of the Federation of the Experimental Biological Societies

International Nuclear Information System (INIS)

1995-01-01

The meeting was about experimental biology and it was discussed topics related to medicine, pharmacology, cellular biology, biophysics, toxicology, physiology, immunology, radiobiology, photobiology, natural products and environment

Summary report on [IAEA] technical meeting of the International Network of Nuclear Reaction Data Centres

International Nuclear Information System (INIS)

Dunaeva, S.; Otsuka, N.; Schwerer, O.

2009-08-01

An IAEA Technical Meeting of the International Network of Nuclear Reaction Data Centres was held at the IAEA Headquarters in Vienna from 25 to 26 May 2009. The meeting was attended by 23 participants from 13 cooperating data centres. A summary of the meeting is given in this report, along with the conclusions, actions, and status report of the participating data centres. (author)

76 FR 30229 - Notice of Meeting of the Advisory Committee on International Law

Science.gov (United States)

2011-05-24

... International Law A meeting of the Advisory Committee on International Law will take place on Monday, June 6, 2011, from 9:30 a.m. to approximately 5:30 p.m., at the George Washington University Law School... accountability mechanisms; the Arctic region and the Law of the Sea Convention; and national security in the...

Biophysics of NASA radiation quality factors

International Nuclear Information System (INIS)

Cucinotta, Francis A.

2015-01-01

NASA has implemented new radiation quality factors (QFs) for projecting cancer risks from space radiation exposures to astronauts. The NASA QFs are based on particle track structure concepts with parameters derived from available radiobiology data, and NASA introduces distinct QFs for solid cancer and leukaemia risk estimates. The NASA model was reviewed by the US National Research Council and approved for use by NASA for risk assessment for International Space Station missions and trade studies of future exploration missions to Mars and other destinations. A key feature of the NASA QFs is to represent the uncertainty in the QF assessments and evaluate the importance of the QF uncertainty to overall uncertainties in cancer risk projections. In this article, the biophysical basis for the probability distribution functions representing QF uncertainties was reviewed, and approaches needed to reduce uncertainties were discussed. (author)

Abstracts and papers of the 1999 International RERTR Meeting

International Nuclear Information System (INIS)

1999-10-01

The papers presented at the 22nd International RERTR Meeting dealt with the following topics: development and testing of new fuel elements (uranium-molybdenum alloys); research reactors core conversion studies (change from highly to moderately or slightly enriched uranium), including both measurements and calculations: spent fuel storage and transportation; production of 99 Mo from low enriched uranium. A number of papers were devoted to the status and future of national RERTR programs

The biophysics of neuronal growth

International Nuclear Information System (INIS)

Franze, Kristian; Guck, Jochen

2010-01-01

For a long time, neuroscience has focused on biochemical, molecular biological and electrophysiological aspects of neuronal physiology and pathology. However, there is a growing body of evidence indicating the importance of physical stimuli for neuronal growth and development. In this review we briefly summarize the historical background of neurobiophysics and give an overview over the current understanding of neuronal growth from a physics perspective. We show how biophysics has so far contributed to a better understanding of neuronal growth and discuss current inconsistencies. Finally, we speculate how biophysics may contribute to the successful treatment of lesions to the central nervous system, which have been considered incurable until very recently.

Biophysical regulation of stem cell differentiation.

Science.gov (United States)

Govey, Peter M; Loiselle, Alayna E; Donahue, Henry J

2013-06-01

Bone adaptation to its mechanical environment, from embryonic through adult life, is thought to be the product of increased osteoblastic differentiation from mesenchymal stem cells. In parallel with tissue-scale loading, these heterogeneous populations of multipotent stem cells are subject to a variety of biophysical cues within their native microenvironments. Bone marrow-derived mesenchymal stem cells-the most broadly studied source of osteoblastic progenitors-undergo osteoblastic differentiation in vitro in response to biophysical signals, including hydrostatic pressure, fluid flow and accompanying shear stress, substrate strain and stiffness, substrate topography, and electromagnetic fields. Furthermore, stem cells may be subject to indirect regulation by mechano-sensing osteocytes positioned to more readily detect these same loading-induced signals within the bone matrix. Such paracrine and juxtacrine regulation of differentiation by osteocytes occurs in vitro. Further studies are needed to confirm both direct and indirect mechanisms of biophysical regulation within the in vivo stem cell niche.

International VLBI Service for Geodesy and Astrometry: General Meeting Proceedings

Science.gov (United States)

Vandenberg, Nancy R. (Editor); Baver, Karen D. (Editor)

2002-01-01

This volume contains the proceedings of the second General Meeting of the International VLBI Service for Geodesy and Astrometry (IVS), held in Tsukuba, Japan, February 4-7, 2002. The contents of this volume also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/gm2002. The key-note of the second GM was prospectives for the future, in keeping with the re-organization of the IAG around the motivation of geodesy as 'an old science with a dynamic future' and noting that providing reference frames for Earth system science that are consistent over decades on the highest accuracy level will provide a challenging role for IVS. The goal of the meeting was to provide an interesting and informative program for a wide cross section of IVS members, including station operators, program managers, and analysts. This volume contains 72 papers and five abstracts of papers presented at the GM. The volume also includes reports about three splinter meetings held in conjunction with the GM: a mini-TOW (Technical Operations Workshop), the third IVS Analysis Workshop and a meeting of the analysis working group on geophysical modeling.

The relationship between fetal biophysical profile and cord blood PH

Directory of Open Access Journals (Sweden)

Valadan M

2009-02-01

Full Text Available "nBackground: The Biophysical Profile (BPP is a noninvasive test that predicts the presence or absence of fetal asphyxia and, ultimately, the risk of fetal death in the antenatal period. Intervention on the basis of an abnormal biophysical profile result has been reported to yield a significant reduction in prenatal mortality, and an association exists between biophysical profile scoring and a decreased cerebral palsy rate in a given population. The BPP evaluates five characteristics: fetal movement, tone, breathing, heart reactivity, and amniotic fluid (AF volume estimation. The purpose of study was to determine whether there are different degree of acidosis at which the biophysical activity (acute marker are affected. "nMethods: In a prospective study of 140 patients undergoing cesarean section before onset of labor, the fetal biophysical profile was performed 24h before the time of cesarean and was matched with cord arterial PH that was obtained from a cord segment (10-20cm that was double clamped after delivery of newborn. (using cord arterial PH less than 7.20 for the diagnosis of acidosis. "nResults: The fetal biophysical profile was found to have a significant relationship with umbilical blood PH. The sensitivity, specificity, positive predictive value, negative predictive value of fetal biophysical profile score were: 88.9%, 88.6%, 50%, 98.1%. "nConclusion: The first manifestations of fetal acidosis are nonreactive nonstress testing and fetal breathing loss; in advanced acidemia fetal movements and fetal tone are compromised. A protocol of antepartum fetal evaluation is suggested based upon the individual biophysical components rather than the score alone.

International Working Group on Life Management of Nuclear Power Plants regular meeting. Working material

International Nuclear Information System (INIS)

1994-01-01

The aim of this meeting is to review the IWG activities in 1992-1993, other relevant activities, national programmes, projects of international organizations and provide recommendations of the Agency's activities, forward programmes in this area, priority scope and content of publications and meetings to be organized and sponsored by the Agency. Refs, figs and tabs

International VLBI Service for Geodesy and Astrometry 2004 General Meeting Proceedings

Science.gov (United States)

Vandenberg, Nancy R. (Editor); Baver, Karen D. (Editor)

2004-01-01

This volume is the proceedings of the third General Meeting of the International VLBI Service for Geodesy and Astromctry IVS), held in Otlawa, Canada, February 9-11,2004. The keynote of the third GM was visions for the next decade following the main theme of "Today's Results and Tomorrow's Vision". with a recognition that the outstanding VLBI results available today are the foundation and motivation for the next generation VLBI system requirements. The goal of the meeting was to provide an interesting and informative program for a wide cross section of IVS members, including station operators, program managers, and analysts.

Biophysical Evaluation of SonoSteam®:

DEFF Research Database (Denmark)

Andersen, Ann Zahle; Duelund, Lars; Brewer, Jonathan R.

and safety evaluations. Our results show that there are no contradictions between data obtained by either approach. However, the biophysical methods draw a much more nuanced picture of the effects and efficiency of the investigated decontamination method, revealing e.g. an exponential dose/response...... relationship between SonoSteam treatment time and changes in collagen I, and a depth dependency in bacterial reduction, which points toward CFU counts overestimating total bacterial reduction. In conclusion the biophysical methods provide a less biased, reproducible and highly detailed system description...

Report of international symposium on the 22nd Japan annual nuclear energy meeting, PNC general meeting and business report about nuclear energy

Energy Technology Data Exchange (ETDEWEB)

NONE

1989-04-15

This conference report consists of three parts, which report the 22nd annual nuclear energy meeting in Japan, including the list of Korean delegates, program and the contents of five session, the conference report for PNC general meeting and the report on international symposium for fruition of nuclear power business. It introduces the main conception and the contents of the symposium.

Biophysical Cancer Transformation Pathway

Czech Academy of Sciences Publication Activity Database

Pokorný, Jiří

2009-01-01

Roč. 28, č. 2 (2009), s. 105-123 ISSN 1536-8378 Institutional research plan: CEZ:AV0Z20670512 Keywords : Biophysics * Cancer * Electromagnetic fields Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 0.729, year: 2009

VIII International Meeting on Lorentzian Geometry

CERN Document Server

Flores, José; Palomo, Francisco; GeLoMa 2016; Lorentzian geometry and related topics

2017-01-01

This volume contains a collection of research papers and useful surveys by experts in the field which provide a representative picture of the current status of this fascinating area. Based on contributions from the VIII International Meeting on Lorentzian Geometry, held at the University of Málaga, Spain, this volume covers topics such as distinguished (maximal, trapped, null, spacelike, constant mean curvature, umbilical...) submanifolds, causal completion of spacetimes, stationary regions and horizons in spacetimes, solitons in semi-Riemannian manifolds, relation between Lorentzian and Finslerian geometries and the oscillator spacetime. In the last decades Lorentzian geometry has experienced a significant impulse, which has transformed it from just a mathematical tool for general relativity to a consolidated branch of differential geometry, interesting in and of itself. Nowadays, this field provides a framework where many different mathematical techniques arise with applications to multiple parts of mathem...

Meeting report: First International Conference on Crimean-Congo hemorrhagic fever.

Science.gov (United States)

Papa, Anna; Weber, Friedemann; Hewson, Roger; Weidmann, Manfred; Koksal, Iftihar; Korukluoglu, Gulay; Mirazimi, Ali

2015-08-01

Crimean-Congo hemorrhagic fever (CCHF) is the most widespread tick-borne disease of humans, occurring from western China to the Balkans in Eurasia and south throughout the length of Africa. Its incidence has increased over the past decade, particularly in Turkey and Iran, and the disease has also emerged in India. Research has been hindered by limited laboratory capacity in many regions where the disease is prevalent, indicating the need for collaboration between investigators in endemic countries and those with greater scientific resources. In an effort to increase such collaboration, the First International Conference on Crimean-Congo hemorrhagic fever was held in Thessaloniki, Greece, from February 13 to 14, 2015. This meeting followed the conclusion of an EU-supported Collaborative Project under the Health Cooperation Work Programme of the 7th Framework Programme (Grant agreement No. 260427). It is expected to be the first in a series of meetings that will bring together researchers from around the world to exchange knowledge and experience on various aspects of CCHF. This report summarizes major presentations by the invited speakers at the First International Conference on CCHF. Copyright © 2015 Elsevier B.V. All rights reserved.

Fast reactor safety: proceedings of the international topical meeting. Volume 2

International Nuclear Information System (INIS)

1985-07-01

The emphasis of this meeting was on the safety-related aspects of fast reactor design, analysis, licensing, construction, and operation. Relative to past meetings, there was less emphasis on the scientific and technological basis for accident assessment. Because of its broad scope, the meeting attracted 217 attendees from a wide cross section of the design, safety analysis, and safety technology communities. Eight countries and two international organizations were represented. A total of 126 papers were presented, with contributions from the United States, France, Japan, the United Kingdom, Germany, and Italy. Sessions covered in Volume 2 include: safety design concepts; operational transient experiments; analysis of seismic and external events; HCDA-related codes, analysis, and experiments; sodium fires; instrumentation and control/PPS design; whole-core accident analysis codes; and impact of safety design considerations on future LMFBR developments

The International Commission of Non-Ionizing Radiation Protection: meeting the challenges in NIR protection

Energy Technology Data Exchange (ETDEWEB)

McKinlay, A [National Radiological Protection Board, Didcot (United Kingdom). ICNIRP

2002-07-01

This paper summarises ICNIRP's brief history from its beginnings as a committee of the International Radiation Protection Association (IRPA) to the present as an independent International Commission, and examines how it has structured itself to meet the challenges in non-ionising radiation (NIR) protection now and in the future.

Minutes of the 23rd meeting of the International Nuclear Data Committee

International Nuclear Information System (INIS)

Nichols, A.L.

2000-06-01

The document contains the reports of the two working groups on 'Nuclear Data Dissemination and Co-ordination' and 'Nuclear Data Technology Transfer and Training', the full report of the 23rd meeting of the International Nuclear Data Committee, and seven appendices

ENS RRFM 2005: 9th international topical meeting on research reactor fuel management. Transactions

International Nuclear Information System (INIS)

2005-01-01

The ENS topical meeting on research reactor fuel management is an annual conference launched successfully in 1997. It has since then grown into well established international forum for the exchange and expertise on all significant aspects of the nuclear fuel cycle of research reactors. Oral presentations at this meeting were divided in the following four sessions: International Topics; Fuel Development, Qualification, Fabrication and Licensing; Reactor Operation, Fuel Safety and Core Conversion; Spent Fuel Management, Back-end Options, Transportation. The three poster sessions were devoted to fuel development, qualification, fabrication and licensing; reactor operation, fuel safety, core conversion, spent fuel; spent fuel management, fuel cycle back-end options, transportation

Proceedings of the 1988 International Meeting on Reduced Enrichment for Research and Test Reactors

Energy Technology Data Exchange (ETDEWEB)

1993-07-01

The international effort to develop and implement new research reactor fuels utilizing low-enriched uranium, instead of highly- enriched uranium, continues to make solid progress. This effort is the cornerstone of a widely shared policy aimed at reducing, and possibly eliminating, international traffic in highly-enriched uranium and the nuclear weapon proliferation concerns associated with this traffic. To foster direct communication and exchange of ideas among the specialists in this area, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at Argonne National Laboratory, sponsored this meeting as the eleventh of a series which began 1978. Individual papers presented at the meeting have been cataloged separately.

Proceedings of the 1988 International Meeting on Reduced Enrichment for Research and Test Reactors

International Nuclear Information System (INIS)

1993-07-01

The international effort to develop and implement new research reactor fuels utilizing low-enriched uranium, instead of highly- enriched uranium, continues to make solid progress. This effort is the cornerstone of a widely shared policy aimed at reducing, and possibly eliminating, international traffic in highly-enriched uranium and the nuclear weapon proliferation concerns associated with this traffic. To foster direct communication and exchange of ideas among the specialists in this area, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at Argonne National Laboratory, sponsored this meeting as the eleventh of a series which began 1978. Individual papers presented at the meeting have been cataloged separately

The third international meeting on genetic disorders in the RAS/MAPK pathway: towards a therapeutic approach.

Science.gov (United States)

Korf, Bruce; Ahmadian, Reza; Allanson, Judith; Aoki, Yoko; Bakker, Annette; Wright, Emma Burkitt; Denger, Brian; Elgersma, Ype; Gelb, Bruce D; Gripp, Karen W; Kerr, Bronwyn; Kontaridis, Maria; Lazaro, Conxi; Linardic, Corinne; Lozano, Reymundo; MacRae, Calum A; Messiaen, Ludwine; Mulero-Navarro, Sonia; Neel, Benjamin; Plotkin, Scott; Rauen, Katherine A; Roberts, Amy; Silva, Alcino J; Sittampalam, Sitta G; Zhang, Chao; Schoyer, Lisa

2015-08-01

"The Third International Meeting on Genetic Disorders in the RAS/MAPK Pathway: Towards a Therapeutic Approach" was held at the Renaissance Orlando at SeaWorld Hotel (August 2-4, 2013). Seventy-one physicians and scientists attended the meeting, and parallel meetings were held by patient advocacy groups (CFC International, Costello Syndrome Family Network, NF Network and Noonan Syndrome Foundation). Parent and patient advocates opened the meeting with a panel discussion to set the stage regarding their hopes and expectations for therapeutic advances. In keeping with the theme on therapeutic development, the sessions followed a progression from description of the phenotype and definition of therapeutic endpoints, to definition of genomic changes, to identification of therapeutic targets in the RAS/MAPK pathway, to preclinical drug development and testing, to clinical trials. These proceedings will review the major points of discussion. © 2015 Wiley Periodicals, Inc.

Abstracts and papers presented at the 2004 international RERTR meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-07-01

Oral and poster presentations of the Meeting covered the following topics: National and international programs related to Reduced Enrichment for Research and Test Reactors (RERTR). Development of new fuel types, testing, fabrication, modelling. Studies of reactor cores conversion from highly enriched to low enriched fuel, including licensing. New and converted reactors. Spent fuel management including storage and transportation. Production of Molybdenum 99 under converted core conditions.

Abstracts and papers presented at the 2004 international RERTR meeting

International Nuclear Information System (INIS)

2005-01-01

Oral and poster presentations of the Meeting covered the following topics: National and international programs related to Reduced Enrichment for Research and Test Reactors (RERTR). Development of new fuel types, testing, fabrication, modelling. Studies of reactor cores conversion from highly enriched to low enriched fuel, including licensing. New and converted reactors. Spent fuel management including storage and transportation. Production of Molybdenum 99 under converted core conditions

Summary report of consultants' meeting on IAEA international database on irradiated nuclear graphite properties

International Nuclear Information System (INIS)

Humbert, D.; Wickham, A.J.

2007-06-01

The '9th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties' was held on 26-27 March 2007 at the IAEA Headquarters, Vienna, Austria. All discussions, recommendations and actions of this Consultants' Meeting are recorded in this report. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database and make recommendations for actions for the next year. This report contains the current status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

Developing A Transdisciplinary Process and Community Partnerships to Anticipate Climate Change at the Local Level: The Role of Biophysical and Sociocultural Calendars

Science.gov (United States)

Kassam, K. A.; Samimi, C.; Trabucco, A.

2017-12-01

Difference is essential to solving the most complex problems faced by humanity. Anthropogenic climate change is one such "wicked problem" that demands cognitive diversity. Biophysical and social scientists must collaborate with scholars from the humanities to address practical issues of concern to local communities, which are at the forefront of impacts of climatic variation. As such, communities of inquirers (e.g. biophysical and social sciences, humanities) must work in tandem with communities of practice (e.g. farmers, fishers, gatherers, herders, hunters). This leads to co-generated knowledge where an adaptation strategy to climatic variation is locally grounded in the biophysical and sociocultural context of the communities where the impacts of climatic variation are most felt. We will present an innovative and `real time' example participatory and transdisciplinary research from an international project where we are developing integrated biophysical and sociocultural calendars, in short, ecological calendars, which are ecologically and culturally grounded in the local context to develop anticipatory capacity to anthropogenic climate change.

78 FR 22263 - Advisory Council on the Standards for Internal Control in the Federal Government; Meeting

Science.gov (United States)

2013-04-15

... GOVERNMENT ACCOUNTABILITY OFFICE Advisory Council on the Standards for Internal Control in the... Standards for Internal Control in the Federal Government; Notice of Meeting. SUMMARY: The US Government Accountability Office (GAO) is initiating efforts to revise the Standards for Internal Control in the Federal...

The physical basis of biochemistry the foundations of molecular biophysics

CERN Document Server

Bergethon, Peter R

1998-01-01

The objective of this book is to provide a unifying approach to the study of biophysical chemistry for the advanced undergraduate who has had a year of physics, organic chem­ istry, calculus, and biology. This book began as a revised edition of Biophysical Chemistry: Molecules to Membranes, which Elizabeth Simons and I coauthored. That short volume was written in an attempt to provide a concise text for a one-semester course in biophysical chemistry at the graduate level. The experience of teaching biophysical chemistry to bi­ ologically oriented students over the last decade has made it clear that the subject requires a more fundamental text that unifies the many threads of modem science: physics, chem­ istry, biology, mathematics, and statistics. This book represents that effort. This volume is not a treatment of modem biophysical chemistry with its rich history and many contro­ versies, although a book on that topic is also needed. The Physical Basis of Biochemistry is an introduction to the philosophy...

Past and Present Biophysical Redundancy of Countries as a Buffer to Changes in Food Supply

Science.gov (United States)

Fader, Marianela; Rulli, Maria Cristina; Carr, Joel; Dell' Angelo, Jampel; D' Odorico, Paolo; Gephart, Jessica A.; Kummu, Matti; Magliocca, Nicholas; Porkka, Miina; Prell, Christina;

Past and present biophysical redundancy of countries as a buffer to changes in food supply

Science.gov (United States)

Fader, Marianela; Rulli, Maria Cristina; Carr, Joel; Dell'Angelo, Jampel; D'Odorico, Paolo; Gephart, Jessica A.; Kummu, Matti; Magliocca, Nicholas; Porkka, Miina; Prell, Christina; Puma, Michael J.; Ratajczak, Zak; Seekell, David A.; Suweis, Samir; Tavoni, Alessandro

2016-05-01

Spatially diverse trends in population growth, climate change, industrialization, urbanization and economic development are expected to change future food supply and demand. These changes may affect the suitability of land for food production, implying elevated risks especially for resource-constrained, food-importing countries. We present the evolution of biophysical redundancy for agricultural production at country level, from 1992 to 2012. Biophysical redundancy, defined as unused biotic and abiotic environmental resources, is represented by the potential food production of ‘spare land’, available water resources (i.e., not already used for human activities), as well as production increases through yield gap closure on cultivated areas and potential agricultural areas. In 2012, the biophysical redundancy of 75 (48) countries, mainly in North Africa, Western Europe, the Middle East and Asia, was insufficient to produce the caloric nutritional needs for at least 50% (25%) of their population during a year. Biophysical redundancy has decreased in the last two decades in 102 out of 155 countries, 11 of these went from high to limited redundancy, and nine of these from limited to very low redundancy. Although the variability of the drivers of change across different countries is high, improvements in yield and population growth have a clear impact on the decreases of redundancy towards the very low redundancy category. We took a more detailed look at countries classified as ‘Low Income Economies (LIEs)’ since they are particularly vulnerable to domestic or external food supply changes, due to their limited capacity to offset for food supply decreases with higher purchasing power on the international market. Currently, nine LIEs have limited or very low biophysical redundancy. Many of these showed a decrease in redundancy over the last two decades, which is not always linked with improvements in per capita food availability.

Fast reactor safety: proceedings of the international topical meeting. Volume 1

Energy Technology Data Exchange (ETDEWEB)

1985-07-01

The emphasis of this meeting was on the safety-related aspects of fast reactor design, analysis, licensing, construction, and operation. Relative to past meetings, there was less emphasis on the scientific and technological basis for accident assessment. Because of its broad scope, the meeting attracted 217 attendees from a wide cross section of the design, safety analysis, and safety technology communities. Eight countries and two international organizations were represented. A total of 126 papers were presented, with contributions from the United States, France, Japan, the United Kingdom, Germany, and Italy. Sessions covered in Volume 1 include: impact of safety and licensing considerations on fast reactor design; safety aspects of innovative designs; intra-subassembly behavior; operational safety; design accommodation of seismic and other external events; natural circulation; safety design concepts; safety implications derived from operational plant data; decay heat removal; and assessment of HCDA consequences.

Fast reactor safety: proceedings of the international topical meeting. Volume 1

International Nuclear Information System (INIS)

1985-07-01

The emphasis of this meeting was on the safety-related aspects of fast reactor design, analysis, licensing, construction, and operation. Relative to past meetings, there was less emphasis on the scientific and technological basis for accident assessment. Because of its broad scope, the meeting attracted 217 attendees from a wide cross section of the design, safety analysis, and safety technology communities. Eight countries and two international organizations were represented. A total of 126 papers were presented, with contributions from the United States, France, Japan, the United Kingdom, Germany, and Italy. Sessions covered in Volume 1 include: impact of safety and licensing considerations on fast reactor design; safety aspects of innovative designs; intra-subassembly behavior; operational safety; design accommodation of seismic and other external events; natural circulation; safety design concepts; safety implications derived from operational plant data; decay heat removal; and assessment of HCDA consequences

Proceedings of the 9. National Meeting on Condensed Matter Physics

International Nuclear Information System (INIS)

1986-01-01

The 9. National Meeting on Condensed Matter Physics presents works developed in the following fields: amorphous materials, atomic and molecular physics, biophysics, crystallography, defects, growth and critical phenomena, instrumentation, liquid crystals, magnetism, matter science/mechanical properties, metals and alloys, optic, magnetic resonance and semiconductors. (M.C.K.) [pt

Proceedings of the 12. National Meeting on Condensed Matter Physics

International Nuclear Information System (INIS)

1989-01-01

The XII National Meeting on Condensed Matter Physics presented works in the areas: atomic and molecular physics; biophysics; crystallography; defects growth and characterization of crystals; instrumentation; liquid crystals; magnetism; science of materials, metals and alloys; magnetic resonance; semiconductors; superconductivity and; surfaces and thin films. (M.C.K.) [pt

Meeting International Society for Technology in Education Competencies with a Problem-Based Learning Video Framework

Science.gov (United States)

Skoretz, Yvonne M.; Cottle, Amy E.

2011-01-01

Meeting International Society for Technology in Education competencies creates a challenge for teachers. The authors provide a problem-based video framework that guides teachers in enhancing 21st century skills to meet those competencies. To keep the focus on the content, the authors suggest teaching the technology skills only at the point the…

Third International Meeting on Next Generation Safeguards: Safeguards-by-Design at Enrichment Facilities

International Nuclear Information System (INIS)

Long, Jon D.; McGinnis, Brent R.; Morgan, James B.; Whitaker, Michael; Lockwood, Dunbar; Shipwash, Jacqueline L.

2011-01-01

The Third International Meeting on Next Generation Safeguards (NGS3) was hosted by the U.S. Department of Energy (DOE)/National Nuclear Security Administration's (NNSA) Office of Nonproliferation and International Security (NIS) in Washington, D.C. on 14-15 December 2010; this meeting focused on the Safeguards-by-Design (SBD) concept. There were approximately 100 participants from 13 countries, comprised of safeguards policy and technical experts from government and industry. Representatives also were present from the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials (ABACC), the European Atomic Energy Agency (Euratom), and the International Atomic Energy Agency (IAEA). The primary objective of this meeting was to exchange views and provide recommendations on implementation of the SBD concept for four specific nuclear fuel cycle facility types: gas centrifuge enrichment plants (GCEPs), GEN III and GEN IV reactors, aqueous reprocessing plants, and mixed oxide fuel fabrication facilities. The general and facility-specific SBD documents generated from the four working groups, which were circulated for comment among working group participants, are intended to provide a substantive contribution to the IAEA's efforts to publish SBD guidance for these specific types of nuclear facilities in the near future. The IAEA has described the SBD concept as an approach in which 'international safeguards are fully integrated into the design process of a new nuclear facility from the initial planning through design, construction, operation, and decommissioning.' As part of the Next Generation Safeguards Initiative (NGSI), the DOE is working to establish SBD as a global norm through DOE laboratory studies, international workshops, engagement with industry and the IAEA, and setting an example through its use in new nuclear facilities in the United States. This paper describes the discussion topics and final recommendations of the Enrichment Facilities Working

77 FR 27468 - Center for Scientific Review, Notice of Closed Meetings

Science.gov (United States)

2012-05-10

..., (Virtual Meeting). Contact Person: Edwin C Clayton, Ph.D., Scientific Review Officer, Center for Scientific...-408-9041, [email protected] . Name of Committee: Biological Chemistry and Macromolecular Biophysics Integrated Review Group; Synthetic and Biological Chemistry B Study Section. Date: May 30-31, 2012. Time: 8...

Global energy modeling - A biophysical approach

Energy Technology Data Exchange (ETDEWEB)

Dale, Michael

2010-09-15

This paper contrasts the standard economic approach to energy modelling with energy models using a biophysical approach. Neither of these approaches includes changing energy-returns-on-investment (EROI) due to declining resource quality or the capital intensive nature of renewable energy sources. Both of these factors will become increasingly important in the future. An extension to the biophysical approach is outlined which encompasses a dynamic EROI function that explicitly incorporates technological learning. The model is used to explore several scenarios of long-term future energy supply especially concerning the global transition to renewable energy sources in the quest for a sustainable energy system.

Biophysical Regulation of Vascular Differentiation and Assembly

CERN Document Server

Gerecht, Sharon

2011-01-01

The ability to grow stem cells in the laboratory and to guide their maturation to functional cells allows us to study the underlying mechanisms that govern vasculature differentiation and assembly in health and disease. Accumulating evidence suggests that early stages of vascular growth are exquisitely tuned by biophysical cues from the microenvironment, yet the scientific understanding of such cellular environments is still in its infancy. Comprehending these processes sufficiently to manipulate them would pave the way to controlling blood vessel growth in therapeutic applications. This book assembles the works and views of experts from various disciplines to provide a unique perspective on how different aspects of its microenvironment regulate the differentiation and assembly of the vasculature. In particular, it describes recent efforts to exploit modern engineering techniques to study and manipulate various biophysical cues. Biophysical Regulation of Vascular Differentiation and Assembly provides an inter...

Biophysics and systems biology.

Science.gov (United States)

Noble, Denis

2010-03-13

Biophysics at the systems level, as distinct from molecular biophysics, acquired its most famous paradigm in the work of Hodgkin and Huxley, who integrated their equations for the nerve impulse in 1952. Their approach has since been extended to other organs of the body, notably including the heart. The modern field of computational biology has expanded rapidly during the first decade of the twenty-first century and, through its contribution to what is now called systems biology, it is set to revise many of the fundamental principles of biology, including the relations between genotypes and phenotypes. Evolutionary theory, in particular, will require re-assessment. To succeed in this, computational and systems biology will need to develop the theoretical framework required to deal with multilevel interactions. While computational power is necessary, and is forthcoming, it is not sufficient. We will also require mathematical insight, perhaps of a nature we have not yet identified. This article is therefore also a challenge to mathematicians to develop such insights.

Large-scale biophysical evaluation of protein PEGylation effects

DEFF Research Database (Denmark)

Vernet, Erik; Popa, Gina; Pozdnyakova, Irina

2016-01-01

PEGylation is the most widely used method to chemically modify protein biopharmaceuticals, but surprisingly limited public data is available on the biophysical effects of protein PEGylation. Here we report the first large-scale study, with site-specific mono-PEGylation of 15 different proteins...... of PEGylation on the thermal stability of a protein based on data generated by circular dichroism (CD), differential scanning calorimetry (DSC), or differential scanning fluorimetry (DSF). In addition, DSF was validated as a fast and inexpensive screening method for thermal unfolding studies of PEGylated...... proteins. Multivariate data analysis revealed clear trends in biophysical properties upon PEGylation for a subset of proteins, although no universal trends were found. Taken together, these findings are important in the consideration of biophysical methods and evaluation of second...

77 FR 12605 - Center for Scientific Review; Notice of Closed Meetings

Science.gov (United States)

2012-03-01

..., (Virtual Meeting). Contact Person: Eduardo A Montalvo, Ph.D., Scientific Review Officer, Center for... Person: Allen Richon, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes...: Chemistry, Biochemistry, Biophysics, and Bioengineering. Date: March 15-20, 2012. Time: 11 a.m. to 5 p.m...

Biophysical models of larval dispersal in the Benguela Current ...

African Journals Online (AJOL)

We synthesise and update results from the suite of biophysical, larval-dispersal models developed in the Benguela Current ecosystem. Biophysical models of larval dispersal use outputs of physical hydrodynamic models as inputs to individual-based models in which biological processes acting during the larval life are ...

Estimation efficiency of usage satellite derived and modelled biophysical products for yield forecasting

Science.gov (United States)

Kolotii, Andrii; Kussul, Nataliia; Skakun, Sergii; Shelestov, Andrii; Ostapenko, Vadim; Oliinyk, Tamara

2015-04-01

Efficient and timely crop monitoring and yield forecasting are important tasks for ensuring of stability and sustainable economic development [1]. As winter crops pay prominent role in agriculture of Ukraine - the main focus of this study is concentrated on winter wheat. In our previous research [2, 3] it was shown that usage of biophysical parameters of crops such as FAPAR (derived from Geoland-2 portal as for SPOT Vegetation data) is far more efficient for crop yield forecasting to NDVI derived from MODIS data - for available data. In our current work efficiency of usage such biophysical parameters as LAI, FAPAR, FCOVER (derived from SPOT Vegetation and PROBA-V data at resolution of 1 km and simulated within WOFOST model) and NDVI product (derived from MODIS) for winter wheat monitoring and yield forecasting is estimated. As the part of crop monitoring workflow (vegetation anomaly detection, vegetation indexes and products analysis) and yield forecasting SPIRITS tool developed by JRC is used. Statistics extraction is done for landcover maps created in SRI within FP-7 SIGMA project. Efficiency of usage satellite based and modelled with WOFOST model biophysical products is estimated. [1] N. Kussul, S. Skakun, A. Shelestov, O. Kussul, "Sensor Web approach to Flood Monitoring and Risk Assessment", in: IGARSS 2013, 21-26 July 2013, Melbourne, Australia, pp. 815-818. [2] F. Kogan, N. Kussul, T. Adamenko, S. Skakun, O. Kravchenko, O. Kryvobok, A. Shelestov, A. Kolotii, O. Kussul, and A. Lavrenyuk, "Winter wheat yield forecasting in Ukraine based on Earth observation, meteorological data and biophysical models," International Journal of Applied Earth Observation and Geoinformation, vol. 23, pp. 192-203, 2013. [3] Kussul O., Kussul N., Skakun S., Kravchenko O., Shelestov A., Kolotii A, "Assessment of relative efficiency of using MODIS data to winter wheat yield forecasting in Ukraine", in: IGARSS 2013, 21-26 July 2013, Melbourne, Australia, pp. 3235 - 3238.

Coding Theory and Applications : 4th International Castle Meeting

CERN Document Server

Malonek, Paula; Vettori, Paolo

2015-01-01

The topics covered in this book, written by researchers at the forefront of their field, represent some of the most relevant research areas in modern coding theory: codes and combinatorial structures, algebraic geometric codes, group codes, quantum codes, convolutional codes, network coding and cryptography. The book includes a survey paper on the interconnections of coding theory with constrained systems, written by an invited speaker, as well as 37 cutting-edge research communications presented at the 4th International Castle Meeting on Coding Theory and Applications (4ICMCTA), held at the Castle of Palmela in September 2014. The event’s scientific program consisted of four invited talks and 39 regular talks by authors from 24 different countries. This conference provided an ideal opportunity for communicating new results, exchanging ideas, strengthening international cooperation, and introducing young researchers into the coding theory community.

Delineating Biophysical Environments of the Sunda Banda Seascape, Indonesia

Directory of Open Access Journals (Sweden)

Mingshu Wang

2015-01-01

Full Text Available The Sunda Banda Seascape (SBS, located in the center of the Coral Triangle, is a global center of marine biodiversity and a conservation priority. We proposed the first biophysical environmental delineation of the SBS using globally available satellite remote sensing and model-assimilated data to categorize this area into unique and meaningful biophysical classes. Specifically, the SBS was partitioned into eight biophysical classes characterized by similar sea surface temperature, chlorophyll a concentration, currents, and salinity patterns. Areas within each class were expected to have similar habitat types and ecosystem functions. Our work supplemented prevailing global marine management schemes by focusing in on a regional scale with finer spatial resolution. It also provided a baseline for academic research, ecological assessments and will facilitate marine spatial planning and conservation activities in the area. In addition, the framework and methods of delineating biophysical environments we presented can be expanded throughout the whole Coral Triangle to support research and conservation activities in this important region.

Structural biophysics

International Nuclear Information System (INIS)

Anon.

1979-01-01

Summaries of research projects conducted during 1978 and 1979 are presented. The structural biophysics group explores the high-resolution structure of biological macromolecules and cell organelles. Specific subject areas include: the basic characteristics of photosynthesis in plants; the chemical composition of individual fly ash particles at the site of their damaging action in tissues; direct analysis of frozen-hydrated biological samples by scanning electron microscopy; yeast genetics; the optical activity of DNA aggregates; measurement and characterization of lipoproteins; function of lipoproteins; and the effect of radiation and pollutants on mammalian cells

IGORR-IV: Proceedings of the fourth meeting of the International Group On Research Reactors

International Nuclear Information System (INIS)

Rosenbalm, K.F.

1995-01-01

The fourth meeting of the International Group on Research Reactors (IGORR-IV) was attended by was good 55 registered participants from 28 organizations in 13 countries, which compares well with the previous meetings. Twenty-nine papers were presented in five sessions over the two-day meeting. Session subjects were: Operating Research Reactors and Facility Upgrades; Research Reactors in Desin and Construction; Research, Development, and Analysis Results of Thermal Hydraulic Calculations, U 3 Si 2 Fuel Performance and Faibrication; Structural Materials Performance; Neutronics; Severe Accident analysis. Written versions of the papers or hard copies of the viewgraphs used are published in these Proceedings

Biophysics of NASA radiation quality factors.

Science.gov (United States)

Cucinotta, Francis A

2015-09-01

NASA has implemented new radiation quality factors (QFs) for projecting cancer risks from space radiation exposures to astronauts. The NASA QFs are based on particle track structure concepts with parameters derived from available radiobiology data, and NASA introduces distinct QFs for solid cancer and leukaemia risk estimates. The NASA model was reviewed by the US National Research Council and approved for use by NASA for risk assessment for International Space Station missions and trade studies of future exploration missions to Mars and other destinations. A key feature of the NASA QFs is to represent the uncertainty in the QF assessments and evaluate the importance of the QF uncertainty to overall uncertainties in cancer risk projections. In this article, the biophysical basis for the probability distribution functions representing QF uncertainties was reviewed, and approaches needed to reduce uncertainties were discussed. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

78 FR 38430 - Notice of Meeting of Advisory Committee on International Law

Science.gov (United States)

2013-06-26

... DEPARTMENT OF STATE [Public Notice 8351] Notice of Meeting of Advisory Committee on International Law Correction In notice document 2013-13719, appearing on page 34702 in the issue of Monday, June 10, 2013, make the following correction: In the third column, in the last paragraph, the entry ``(202-776...

Recent progress in Biophysics

International Nuclear Information System (INIS)

Bemski, G.

1980-03-01

Recent progress in biophysics is reviewed, and three examples of the use of physical techniques and ideas in biological research are given. The first one deals with the oxygen transporting protein-hemoglobin, the second one with photosynthesis, and the third one with image formation, using nuclear magnetic resonance. (Author) [pt

Fast reactor safety: proceedings of the international topical meeting. Volume 2. [R

Energy Technology Data Exchange (ETDEWEB)

1985-07-01

The emphasis of this meeting was on the safety-related aspects of fast reactor design, analysis, licensing, construction, and operation. Relative to past meetings, there was less emphasis on the scientific and technological basis for accident assessment. Because of its broad scope, the meeting attracted 217 attendees from a wide cross section of the design, safety analysis, and safety technology communities. Eight countries and two international organizations were represented. A total of 126 papers were presented, with contributions from the United States, France, Japan, the United Kingdom, Germany, and Italy. Sessions covered in Volume 2 include: safety design concepts; operational transient experiments; analysis of seismic and external events; HCDA-related codes, analysis, and experiments; sodium fires; instrumentation and control/PPS design; whole-core accident analysis codes; and impact of safety design considerations on future LMFBR developments.

IAEA International Database on Irradiated Nuclear Graphite Properties. 7th meeting of the Technical Steering Committee

International Nuclear Information System (INIS)

Humbert, D.; Wickham, A.J.

2005-06-01

This report summarizes the Consultant Meeting '7th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties' held on 16-17 March 2005 at the IAEA Headquarters, Vienna, Austria. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database and to make recommendations for actions for the next year. The purposes of the meeting were fully met. This report contains the current status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

IAEA International Database on Irradiated Nuclear Graphite Properties. 6th meeting of the Technical Steering Committee

International Nuclear Information System (INIS)

Humbert, D.; Wickham, A.J.

2004-12-01

This report summarizes the Consultant Meeting 6th Meeting of the Technical Steering Committee for the International Database on Irradiated Nuclear Graphite Properties' held on 16-17 September 2004 at Plas Tan-Y-Bwlch, Maentwrog, Gwynedd, UK. The purposes of the meeting were to review the matters and actions identified in the previous meeting, undertake a review of the current status of the database and to make recommendations for actions for the next year. The purposes of the meeting were fully met. This report contains the current status of the identified actions as well as a summary of the recommendations on enhancements to the database. (author)

MODELLING BIOPHYSICAL PARAMETERS OF MAIZE USING LANDSAT 8 TIME SERIES

Directory of Open Access Journals (Sweden)

T. Dahms

2016-06-01

Full Text Available Open and free access to multi-frequent high-resolution data (e.g. Sentinel – 2 will fortify agricultural applications based on satellite data. The temporal and spatial resolution of these remote sensing datasets directly affects the applicability of remote sensing methods, for instance a robust retrieving of biophysical parameters over the entire growing season with very high geometric resolution. In this study we use machine learning methods to predict biophysical parameters, namely the fraction of absorbed photosynthetic radiation (FPAR, the leaf area index (LAI and the chlorophyll content, from high resolution remote sensing. 30 Landsat 8 OLI scenes were available in our study region in Mecklenburg-Western Pomerania, Germany. In-situ data were weekly to bi-weekly collected on 18 maize plots throughout the summer season 2015. The study aims at an optimized prediction of biophysical parameters and the identification of the best explaining spectral bands and vegetation indices. For this purpose, we used the entire in-situ dataset from 24.03.2015 to 15.10.2015. Random forest and conditional inference forests were used because of their explicit strong exploratory and predictive character. Variable importance measures allowed for analysing the relation between the biophysical parameters with respect to the spectral response, and the performance of the two approaches over the plant stock evolvement. Classical random forest regression outreached the performance of conditional inference forests, in particular when modelling the biophysical parameters over the entire growing period. For example, modelling biophysical parameters of maize for the entire vegetation period using random forests yielded: FPAR: R² = 0.85; RMSE = 0.11; LAI: R² = 0.64; RMSE = 0.9 and chlorophyll content (SPAD: R² = 0.80; RMSE=4.9. Our results demonstrate the great potential in using machine-learning methods for the interpretation of long-term multi-frequent remote sensing

Modelling Biophysical Parameters of Maize Using Landsat 8 Time Series

Science.gov (United States)

Dahms, Thorsten; Seissiger, Sylvia; Conrad, Christopher; Borg, Erik

2016-06-01

Open and free access to multi-frequent high-resolution data (e.g. Sentinel - 2) will fortify agricultural applications based on satellite data. The temporal and spatial resolution of these remote sensing datasets directly affects the applicability of remote sensing methods, for instance a robust retrieving of biophysical parameters over the entire growing season with very high geometric resolution. In this study we use machine learning methods to predict biophysical parameters, namely the fraction of absorbed photosynthetic radiation (FPAR), the leaf area index (LAI) and the chlorophyll content, from high resolution remote sensing. 30 Landsat 8 OLI scenes were available in our study region in Mecklenburg-Western Pomerania, Germany. In-situ data were weekly to bi-weekly collected on 18 maize plots throughout the summer season 2015. The study aims at an optimized prediction of biophysical parameters and the identification of the best explaining spectral bands and vegetation indices. For this purpose, we used the entire in-situ dataset from 24.03.2015 to 15.10.2015. Random forest and conditional inference forests were used because of their explicit strong exploratory and predictive character. Variable importance measures allowed for analysing the relation between the biophysical parameters with respect to the spectral response, and the performance of the two approaches over the plant stock evolvement. Classical random forest regression outreached the performance of conditional inference forests, in particular when modelling the biophysical parameters over the entire growing period. For example, modelling biophysical parameters of maize for the entire vegetation period using random forests yielded: FPAR: R² = 0.85; RMSE = 0.11; LAI: R² = 0.64; RMSE = 0.9 and chlorophyll content (SPAD): R² = 0.80; RMSE=4.9. Our results demonstrate the great potential in using machine-learning methods for the interpretation of long-term multi-frequent remote sensing datasets to model

Social media in radiology: early trends in Twitter microblogging at radiology's largest international meeting.

Science.gov (United States)

Hawkins, C Matthew; Duszak, Richard; Rawson, James V

2014-04-01

Twitter is a social media microblogging platform that allows rapid exchange of information between individuals. Despite its widespread acceptance and use at various other medical specialty meetings, there are no published data evaluating its use at radiology meetings. The purpose of this study is to quantitatively and qualitatively evaluate the use of Twitter as a microblogging platform at recent RSNA annual meetings. Twitter activity meta-data tagged with official meeting hashtags #RSNA11 and #RSNA12 were collected and analyzed. Multiple metrics were evaluated, including daily and hourly Twitter activity, frequency of microblogging activity over time, characteristics of the 100 most active Twitter users at each meeting, characteristics of meeting-related tweets, and the geographic origin of meeting microbloggers. The use of Twitter microblogging increased by at least 30% by all identifiable meaningful metrics between the 2011 and 2012 RSNA annual meetings, including total tweets, tweets per day, activity of the most active microbloggers, and total number of microbloggers. Similar increases were observed in numbers of North American and international microbloggers. Markedly increased use of the Twitter microblogging platform at recent RSNA annual meetings demonstrates the potential to leverage this technology to engage meeting attendees, improve scientific sessions, and promote improved collaboration at national radiology meetings. Copyright © 2014 American College of Radiology. Published by Elsevier Inc. All rights reserved.

Medical laboratories in sub-Saharan Africa that meet international quality standards.

Science.gov (United States)

Schroeder, Lee F; Amukele, Timothy

2014-06-01

A recent survey of laboratories in Kampala, Uganda, demonstrated that only 0.3% of laboratories (3/954) met international quality standards. To benchmark laboratory quality throughout the rest of sub-Saharan Africa (SSA), we compiled a list of SSA laboratories meeting international quality standards. Accrediting bodies were queried via online registries or direct communication in May 2013. There were 380 laboratories accredited to international standards in SSA. Ninety-one percent were in South Africa. Thirty-seven of 49 countries had no laboratories accredited to international quality standards. Accredited laboratory density (per million people) in South Africa, Namibia, and Botswana were similar to those in many European countries. Single variable linear regression showed a correlation between accredited laboratory density and health expenditures per person (adjusted R(2) = 0.81, P clinical laboratory. For those that do, there is a strong correlation between country-specific accredited laboratory density and per-capita health expenditures. Copyright© by the American Society for Clinical Pathology.

International VLBI Service for Geodesy and Astrometry: 2000 General Meeting Proceedings

Science.gov (United States)

Vandenberg, Nancy R. (Editor); Baver, Karen D. (Editor)

2000-01-01

This volume is the proceedings of the first General Meeting of the International Very Long Base Interferometry (VLBI) Service for Geodesy and Astrometry (IVS), held in Koetzting, Germany, February 21-24, 2000. The content of this volume also appears on the IVS web site at: http://ivscc.gsfc.nasa.gov/publications/gm2000. The goal of the program committee for the General Meeting was to provide an interesting and informative program for a wide cross section of IVS members, including station operators, program managers, and analysts. The program included reports, tutorials, invited and contributed papers, and poster presentations. The tutorial papers should be particularly useful references because each one provides an overview and introduction to a topic relevant to VLBI.

Final report for Conference Support Grant "From Computational Biophysics to Systems Biology - CBSB12"

Energy Technology Data Exchange (ETDEWEB)

Hansmann, Ulrich H.E.

2012-07-02

This report summarizes the outcome of the international workshop From Computational Biophysics to Systems Biology (CBSB12) which was held June 3-5, 2012, at the University of Tennessee Conference Center in Knoxville, TN, and supported by DOE through the Conference Support Grant 120174. The purpose of CBSB12 was to provide a forum for the interaction between a data-mining interested systems biology community and a simulation and first-principle oriented computational biophysics/biochemistry community. CBSB12 was the sixth in a series of workshops of the same name organized in recent years, and the second that has been held in the USA. As in previous years, it gave researchers from physics, biology, and computer science an opportunity to acquaint each other with current trends in computational biophysics and systems biology, to explore venues of cooperation, and to establish together a detailed understanding of cells at a molecular level. The conference grant of $10,000 was used to cover registration fees and provide travel fellowships to selected students and postdoctoral scientists. By educating graduate students and providing a forum for young scientists to perform research into the working of cells at a molecular level, the workshop adds to DOE's mission of paving the way to exploit the abilities of living systems to capture, store and utilize energy.

Handbook of Single-Molecule Biophysics

CERN Document Server

Hinterdorfer, Peter

2009-01-01

The last decade has seen the development of a number of novel biophysical methods that allow the manipulation and study of individual biomolecules. The ability to monitor biological processes at this fundamental level of sensitivity has given rise to an improved understanding of the underlying molecular mechanisms. Through the removal of ensemble averaging, distributions and fluctuations of molecular properties can be characterized, transient intermediates identified, and catalytic mechanisms elucidated. By applying forces on biomolecules while monitoring their activity, important information can be obtained on how proteins couple function to structure. The Handbook of Single-Molecule Biophysics provides an introduction to these techniques and presents an extensive discussion of the new biological insights obtained from them. Coverage includes: Experimental techniques to monitor and manipulate individual biomolecules The use of single-molecule techniques in super-resolution and functional imaging Single-molec...

Abstracts and available papers presented at the 2005 International RERTR Meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-07-01

Oral and poster presentations of the Meeting covered the following topics: National and international programs related to Reduced Enrichment for Research and Test Reactors (RERTR). Development of new fuel types, testing, fabrication, modelling. Studies of reactor cores conversion from highly enriched to low enriched fuel, including licensing. New and converted reactors. Spent fuel management including storage and transportation. Production of Molybdenum 99 under converted core conditions.

IGORR-IV: Proceedings of the fourth meeting of the International Group On Research Reactors

Energy Technology Data Exchange (ETDEWEB)

Rosenbalm, K F [comp.

1995-07-01

The fourth meeting of the International Group on Research Reactors (IGORR-IV) was attended by was good 55 registered participants from 28 organizations in 13 countries, which compares well with the previous meetings. Twenty-nine papers were presented in five sessions over the two-day meeting. Session subjects were: Operating Research Reactors and Facility Upgrades; Research Reactors in Desin and Construction; Research, Development, and Analysis Results of Thermal Hydraulic Calculations, U{sub 3}Si{sub 2} Fuel Performance and Faibrication; Structural Materials Performance; Neutronics; Severe Accident analysis. Written versions of the papers or hard copies of the viewgraphs used are published in these Proceedings.

Biophysical impacts of climate-smart agriculture in the Midwest United States.

Science.gov (United States)

Bagley, Justin E; Miller, Jesse; Bernacchi, Carl J

2015-09-01

The potential impacts of climate change in the Midwest United States present unprecedented challenges to regional agriculture. In response to these challenges, a variety of climate-smart agricultural methodologies have been proposed to retain or improve crop yields, reduce agricultural greenhouse gas emissions, retain soil quality and increase climate resilience of agricultural systems. One component that is commonly neglected when assessing the environmental impacts of climate-smart agriculture is the biophysical impacts, where changes in ecosystem fluxes and storage of moisture and energy lead to perturbations in local climate and water availability. Using a combination of observational data and an agroecosystem model, a series of climate-smart agricultural scenarios were assessed to determine the biophysical impacts these techniques have in the Midwest United States. The first scenario extended the growing season for existing crops using future temperature and CO2 concentrations. The second scenario examined the biophysical impacts of no-till agriculture and the impacts of annually retaining crop debris. Finally, the third scenario evaluated the potential impacts that the adoption of perennial cultivars had on biophysical quantities. Each of these scenarios was found to have significant biophysical impacts. However, the timing and magnitude of the biophysical impacts differed between scenarios. © 2014 John Wiley & Sons Ltd.

Scientific Meetings Database: A New Tool for CTBT-Related International Cooperation

Energy Technology Data Exchange (ETDEWEB)

Knapik, Jerzy F.; Girven, Mary L.

1999-08-20

The mission of international cooperation is defined in the Comprehensive Nuclear-Test-Ban Treaty (CTBT). Ways and means of implementation were the subject of discussion during the International Cooperation Workshop held in Vienna in November 1998, and during the Regional Workshop for CTBTO International Cooperation held in Cairo, Egypt in June 1999. In particular, a database of ''Scientific and Technical Meetings Directly or Indirectly Related to CTBT Verification-Related Technologies'' was developed by the CTBTO PrepCom/PTS/International Cooperation section and integrated into the organization's various web sites in cooperation with the U.S. Department of Energy CTBT Research and Development Program. This database, the structure and use of which is described in this paper/presentation is meant to assist the CTBT-related scientific community in identifying worldwide expertise in the CTBT verification-related technologies and should help experts, particularly those of less technologically advanced States Signatories, to strengthen contacts and to pursue international cooperation under the Tredy regime. Specific opportunities for international cooperation, in particular those provided by active participation in the use and further development of this database, are presented in this paper and/or presentation.

78 FR 52206 - Center For Scientific Review; Notice of Closed Meetings

Science.gov (United States)

2013-08-22

...: Biophysics, Biochemistry and Chemistry. Date: September 18-19, 2013. Time: 8:00 a.m. to 3:00 p.m. Agenda: To..., Bethesda, MD 20892 (Virtual Meeting). Contact Person: John L Bowers, Ph.D., Scientific Review Officer..., Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701...

78 FR 36789 - Center for Scientific Review; Notice of Closed Meetings

Science.gov (United States)

2013-06-19

.... Contact Person: Aruna K Behera, Ph.D., Scientific Review Officer, Center for Scientific Review, National...: Biochemistry & Macromolecular Biophysics. Date: July 15-17, 2013. Time: 8:00 a.m. to 12:00 p.m. Agenda: To..., Bethesda, MD 20892 (Virtual Meeting). Contact Person: James W Mack, Ph.D., Scientific Review Officer...

Role of Membrane Biophysics in Alzheimer's - related cell pathways

Directory of Open Access Journals (Sweden)

Donghui eZhu

2015-05-01

Full Text Available Cellular membrane alterations are commonly observed in many diseases, including Alzheimer’s disease (AD. Membrane biophysical properties, such as membrane molecular order, membrane fluidity, organization of lipid rafts, and adhesion between membrane and cytoskeleton, play an important role in various cellular activities and functions. While membrane biophysics impacts a broad range of cellular pathways, this review addresses the role of membrane biophysics in amyloid-β peptide aggregation, Aβ-induced oxidative pathways, amyloid precursor protein processing, and cerebral endothelial functions in AD. Understanding the mechanism(s underlying the effects of cell membrane properties on cellular processes should shed light on the development of new preventive and therapeutic strategies for this devastating disease.

78 FR 19062 - U.S. Department of State Advisory Committee on Private International Law (ACPIL): Public Meeting...

Science.gov (United States)

2013-03-28

... International Law (ACPIL): Public Meeting on Electronic Commerce The Office of the Assistant Legal Adviser for... UNCITRAL's Working Group IV (electronic commerce), the UNCITRAL Secretariat has prepared draft provisions... on electronic transferable records. The public meeting will take place on Tuesday, April 30, 2013...

77 FR 1548 - Advisory Committee on International Economic Policy; Notice of Open Meeting

Science.gov (United States)

2012-01-10

... and challenges in international economic policy. The meeting will examine a New Focus on Investment: Attracting Inbound Foreign Direct Investment to the United States, and will highlight the U.S.-Turkey Economic Partnership Commission. Subcommittee reports will be led by the Investment Subcommittee, the...

78 FR 2709 - Advisory Committee on International Economic Policy; Notice of Open Meeting

Science.gov (United States)

2013-01-14

... hosted by the Assistant Secretary of State for Economic and Business Affairs Jose W. Fernandez and... Subcommittee, the Subcommittee on Women in International Economic Policy, and the Stakeholder Advisory Board on... Guidelines for Multinational Enterprises. This meeting is open to public participation, though seating is...

Biophysics of molecular gastronomy.

Science.gov (United States)

Brenner, Michael P; Sörensen, Pia M

2015-03-26

Chefs and scientists exploring biophysical processes have given rise to molecular gastronomy. In this Commentary, we describe how a scientific understanding of recipes and techniques facilitates the development of new textures and expands the flavor palette. The new dishes that result engage our senses in unexpected ways. PAPERCLIP. Copyright © 2015 Elsevier Inc. All rights reserved.

Proceedings of the international topical meeting on nuclear and hazardous waste management

International Nuclear Information System (INIS)

Anon.

1988-01-01

This book contains the proceedings of the 1988 International Topical Meeting on Nuclear and Hazardous Waste Management. Included are the following articles: Defense radioactive waste management: status and challenges, Secrets of successful siting legislation for low-level radioactive waste disposal facilities, A generic hazardous waste management training program, Status of industry standards for decommissioning of nuclear facilities

Biotic games and cloud experimentation as novel media for biophysics education

Science.gov (United States)

Riedel-Kruse, Ingmar; Blikstein, Paulo

2014-03-01

First-hand, open-ended experimentation is key for effective formal and informal biophysics education. We developed, tested and assessed multiple new platforms that enable students and children to directly interact with and learn about microscopic biophysical processes: (1) Biotic games that enable local and online play using galvano- and photo-tactic stimulation of micro-swimmers, illustrating concepts such as biased random walks, Low Reynolds number hydrodynamics, and Brownian motion; (2) an undergraduate course where students learn optics, electronics, micro-fluidics, real time image analysis, and instrument control by building biotic games; and (3) a graduate class on the biophysics of multi-cellular systems that contains a cloud experimentation lab enabling students to execute open-ended chemotaxis experiments on slimemolds online, analyze their data, and build biophysical models. Our work aims to generate the equivalent excitement and educational impact for biophysics as robotics and video games have had for mechatronics and computer science, respectively. We also discuss how scaled-up cloud experimentation systems can support MOOCs with true lab components and life-science research in general.

76 FR 4987 - Advisory Committee on International Economic Policy; Notice of Open Meeting

Science.gov (United States)

2011-01-27

... Secretary of State for Economic, Energy, and Business Affairs Jose W. Fernandez and Committee Chair Ted... Subcommittee, the Economic Sanctions Subcommittee, and the Subcommittee on Women in International Economic Policy. This meeting is open to public participation, though seating is limited. Entry to the building is...

Proceedings of the 1978 international meeting on reduced enrichment for research and test reactors

Energy Technology Data Exchange (ETDEWEB)

Travelli, A [Argonne National Laboratory, Argonne, IL (United States)

1993-08-01

November 9-10, 1978, marked the first of what has become an annual event - the International Meeting on Reduced Enrichment for Research and Test Reactors (RERTR). The RERTR Program had been started only three months earlier, and the meeting brought together for the first time many people who became major program participants in later years. This first meeting emphasized fuel development, and while it established the basis for all later meetings, it was unique in several respects. It was a time of feeling each other out, and of sharing new ideas, concerns, and hopes. In the absence of an established precedent, a number of participants came with written papers while others made only verbal presentations. Informality added spice and special importance to the discussions at the end of each presentation and, especially, to the panel discussion at the end of the meeting. An important achievement was a consensus on near-, medium-, and long-term density goals for the various fuels. This consensus resulted in a list written on the blackboard at the end of the panel discussion, and reproduced on page 216, which outlined the goals of each fabricator. Luckily, both presentations and discussions were recorded on audio tape. These recordings were transcribed and used to complete the informal presentations and to append the discussions at the end of each presentation. Considerable effort was expended in clearing the transcribed papers and key discussions with the participants. A few issues could not be resolved quickly, and in the frantic rush of those early years, these proceedings were set aside. Believing that the proceedings of this first meeting are important as a historical record of the beginning of the international RERTR effort, we have recently dusted off the manuscript and finished our editing job.

Proceedings of the 1978 international meeting on reduced enrichment for research and test reactors

International Nuclear Information System (INIS)

Travelli, A.

1993-08-01

November 9-10, 1978, marked the first of what has become an annual event - the International Meeting on Reduced Enrichment for Research and Test Reactors (RERTR). The RERTR Program had been started only three months earlier, and the meeting brought together for the first time many people who became major program participants in later years. This first meeting emphasized fuel development, and while it established the basis for all later meetings, it was unique in several respects. It was a time of feeling each other out, and of sharing new ideas, concerns, and hopes. In the absence of an established precedent, a number of participants came with written papers while others made only verbal presentations. Informality added spice and special importance to the discussions at the end of each presentation and, especially, to the panel discussion at the end of the meeting. An important achievement was a consensus on near-, medium-, and long-term density goals for the various fuels. This consensus resulted in a list written on the blackboard at the end of the panel discussion, and reproduced on page 216, which outlined the goals of each fabricator. Luckily, both presentations and discussions were recorded on audio tape. These recordings were transcribed and used to complete the informal presentations and to append the discussions at the end of each presentation. Considerable effort was expended in clearing the transcribed papers and key discussions with the participants. A few issues could not be resolved quickly, and in the frantic rush of those early years, these proceedings were set aside. Believing that the proceedings of this first meeting are important as a historical record of the beginning of the international RERTR effort, we have recently dusted off the manuscript and finished our editing job

Co-ordination of the international network of nuclear structure and decay data evaluators. Summary report of an IAEA advisory group meeting

Energy Technology Data Exchange (ETDEWEB)

Pronyaev, V G

2001-02-01

The IAEA Nuclear Data Section convened the fourteenth meeting of the International Nuclear Structure and Decay Data Evaluators Network at IAEA Headquarters, Vienna, 4-7 December 2000. The meeting was attended by 22 scientists from 7 Member States and 1 international organization concerned with compilation, evaluation, and dissemination of nuclear structure and decay data. The present document contains a meeting summary, the recommendations, the data center reports and proposals considered by the participants. (author)

Preface: Special Topic on Single-Molecule Biophysics.

Science.gov (United States)

Makarov, Dmitrii E; Schuler, Benjamin

2018-03-28

Single-molecule measurements are now almost routinely used to study biological systems and processes. The scope of this special topic emphasizes the physics side of single-molecule observations, with the goal of highlighting new developments in physical techniques as well as conceptual insights that single-molecule measurements bring to biophysics. This issue also comprises recent advances in theoretical physical models of single-molecule phenomena, interpretation of single-molecule signals, and fundamental areas of statistical mechanics that are related to single-molecule observations. A particular goal is to illustrate the increasing synergy between theory, simulation, and experiment in single-molecule biophysics.

Biophysical shunt theory for neuropsychopathology: Part I.

Science.gov (United States)

Naisberg, Y; Avnon, M; Weizman, A

1995-11-01

We present a new model of the origin of schizophrenia based on biophysical ionic shunts in neuronal (electrical) pathways. Microstructural and molecular evidence is presented for the way in which changes in the neuronal membrane ionic channels may facilitate membrane property rearrangement, leading to a change in the density and composition of the ion channel charge which in turn causes a change in ionic flow orientation and distribution. We suggest that, under abnormal conditions, ionic flow shunts are created which redirect the biophysical collateral neuronal (electrical) pathways, resulting in psychiatric signs and symptoms. This model is complementary to the biological basis of schizophrenia.

Proceedings from an international consensus meeting on posttransplantation diabetes mellitus : recommendations and future directions

NARCIS (Netherlands)

Sharif, A.; Hecking, M.; de Vries, A. P. J.; Porrini, E.; Hornum, M.; Rasoul-Rockenschaub, S.; Berlakovich, G.; Krebs, M.; Kautzky-Willer, A.; Schernthaner, G.; Marchetti, P.; Pacini, G.; Ojo, A.; Takahara, S.; Larsen, J. L.; Budde, K.; Eller, K.; Pascual, J.; Jardine, A.; Bakker, S. J. L.; Valderhaug, T. G.; Jenssen, T. G.; Cohney, S.; Saeemann, M. D.

A consensus meeting was held in Vienna on September 8-9, 2013, to discuss diagnostic and therapeutic challenges surrounding development of diabetes mellitus after transplantation. The International Expert Panel comprised 24 transplant nephrologists, surgeons, diabetologists and clinical scientists,

Proceedings from an international consensus meeting on posttransplantation diabetes mellitus: recommendations and future directions

DEFF Research Database (Denmark)

Sharif, A.; Hecking, M.; de Vries, A.P.

2014-01-01

A consensus meeting was held in Vienna on September 8-9, 2013, to discuss diagnostic and therapeutic challenges surrounding development of diabetes mellitus after transplantation. The International Expert Panel comprised 24 transplant nephrologists, surgeons, diabetologists and clinical scientist...

International topical meeting. Research Reactor Fuel Management (RRFM) and meeting of the International Group on Reactor Research (IGORR)

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

Nuclear research and test reactors have been in operation for over 60 years, over 270 research reactors are currently operating in more than 50 countries. This meeting is dedicated to different aspects of research reactor fuels: new fuels for new reactors, the conversion to low enriched uranium fuels, spent fuel management and computational tools for core simulation. About 80 contributions are reported in this document, they are organized into 7 sessions: 1) international topics and overview on new projects and fuel, 2) new projects and upgrades, 3) fuel development, 4) optimisation and research reactor utilisation, 5) innovative methods in research reactors physics, 6) safety, operation and research reactor conversion, 7) fuel back-end management, and a poster session. Experience from Australian, Romanian, Libyan, Syrian, Vietnamese, South-African and Ghana research reactors are reported among other things. The Russian program for research reactor spent fuel management is described and the status of the American-driven program for the conversion to low enriched uranium fuels is presented. (A.C.)

77 FR 57180 - Advisory Committee on International Economic Policy; Notice of Open Meeting

Science.gov (United States)

2012-09-17

... of State for Economic and Business Affairs Jose W. Fernandez and Committee Chair Ted Kassinger. The... on Women in International Economic Policy, and the Stakeholder Advisory Board on the U.S. National... Enterprises. This meeting is open to public participation, though seating is limited. Entry to the building is...

77 FR 33014 - Advisory Committee on International Economic Policy; Notice of Open Meeting

Science.gov (United States)

2012-06-04

... of State for Economic and Business Affairs Jose W. Fernandez and Committee Chair Ted Kassinger. The... Subcommittee, the Sanctions Subcommittee, the Subcommittee on Women in International Economic Policy, and the...://www.state.gov/e/eb/adcom/aciep/index.htm for updates. This meeting is open to public participation...

Mass spectrometry in structural biology and biophysics architecture, dynamics, and interaction of biomolecules

CERN Document Server

Kaltashov, Igor A; Desiderio, Dominic M; Nibbering, Nico M

2012-01-01

The definitive guide to mass spectrometry techniques in biology and biophysics The use of mass spectrometry (MS) to study the architecture and dynamics of proteins is increasingly common within the biophysical community, and Mass Spectrometry in Structural Biology and Biophysics: Architecture, Dynamics, and Interaction of Biomolecules, Second Edition provides readers with detailed, systematic coverage of the current state of the art. Offering an unrivalled overview of modern MS-based armamentarium that can be used to solve the most challenging problems in biophysics, structural biol

PREFACE: Young Researcher Meeting, Trieste 2013

Science.gov (United States)

Agostini, F.; Antolini, C.; Aversa, R.; Cattani, G.; Martinelli, M.; Mazzaferro, L.; Migliaccio, M.; Paci, F.; Pietrobon, D.; Ricci Pacifici, D.; Stellato, F.; Veneziani, M.

2013-12-01

YRM logo The Young Researcher Meeting (www.yrmr.it) has been a rapidly growing event for the last few years. Together with other initiatives which have emerged in several research areas, the young researcher meeting marks the awareness and the desire of PhD students, postdoctoral fellows and young researchers to play a major role in scientific progress. Devoted to the discussion and the interchange of new developments and ideas in physics, the meeting is primarily aimed at graduate students and postdoctoral researchers, who are encouraged to present their work in an informal atmosphere. One of the main purposes of the conference is to create an international network of young researchers, both experimentalists and theorists, and fruitful collaborations across the different branches of physics. Born in Rome in 2009, after three editions that strengthened it, the Young Researcher Meeting 2013 was held in Trieste. Propelled by the past success, the fourth meeting was a two-day conference on 3-4June. It was sponsored by the International School for Advanced Studies - SISSA - and the University of Padova, thus acquiring an even further international drive. In this volume, we collect some of the contributions that were presented at the conference. They cover topics in astrophysics and cosmology, particle and theoretical physics, soft and condensed matter, biophysics and medical physics. YRM Organising and Editorial Committee Fabio Agostini (fabio.agostini@roma2.infn.it) Dipartimento di Fisica, Università di Roma 'Tor Vergata' Via della Ricerca Scientifica 1, 00133 Roma, Italy Claudia Antolini (claudia.antolini@sissa.it) SISSA - Scuola Internazionale Superiore di Studi Avanzati Via Bonomea 265, 34136 Trieste, Italy Rossella Aversa (raversa@sissa.it) SISSA - Scuola Internazionale Superiore di Studi Avanzati Via Bonomea 265, 34136 Trieste, Italy Giordano Cattani (giordano.cattani@gmail.com) Matteo Martinelli (mmartin@sissa.it) SISSA - Scuola Internazionale Superiore di

Comparison of biophysical factors influencing on emphysema quantification with low-dose CT

Science.gov (United States)

Heo, Chang Yong; Kim, Jong Hyo

2014-03-01

Emphysema Index(EI) measurements in MDCT is known to be influenced by various biophysical factors such as total lung volume, and body size. We investigated the association of the four biophysical factors with emphysema index in low-dose MDCT. In particular, we attempted to identify a potentially stronger biophysical factor than total lung volume. A total of 400 low-dose MDCT volumes taken at 120kVp, 40mAs, 1mm thickness, and B30f reconstruction kernel were used. The lungs, airways, and pulmonary vessels were automatically segmented, and two Emphysema Indices, relative area below -950HU(RA950) and 15th percentile(Perc15), were extracted from the segmented lungs. The biophysical factors such as total lung volume(TLV), mode of lung attenuation(ModLA), effective body diameter(EBD), and the water equivalent body diameter(WBD) were estimated from the segmented lung and body area. The association of biophysical factors with emphysema indices were evaluated by correlation coefficients. The mean emphysema indices were 8.3±5.5(%) in RA950, and -930±18(HU) in Perc15. The estimates of biophysical factors were 4.7±1.0(L) in TLV, -901±21(HU) in ModLA, 26.9±2.2(cm) in EBD, and 25.9±2.6(cm) in WBD. The correlation coefficients of biophysical factors with RA950 were 0.73 in TLV, 0.94 in ModLA, 0.31 in EBD, and 0.18 WBD, the ones with Perc15 were 0.74 in TLV, 0.98 in ModLA, 0.29 in EBD, and 0.15 WBD. Study results revealed that two biophysical factors, TLV and ModLA, mostly affects the emphysema indices. In particular, the ModLA exhibited strongest correlation of 0.98 with Perc15, which indicating the ModLA is the most significant confounding biophysical factor in emphysema indices measurement.

Co-ordination of the international network of nuclear structure and decay data evaluators. Summary report of an IAEA advisory group meeting

International Nuclear Information System (INIS)

Pronyaev, V.G.

1999-03-01

The IAEA Nuclear Data Section convened the thirteenth meeting of the International Nuclear Structure and Decay Data Evaluators Network at the IAEA Headquarters, Vienna, 14-17 December 1998. The meeting was attended by 30 scientists from 10 Member States and 2 international organizations concerned with compilation, evaluation, and dissemination of nuclear structure and decay data. The present document contains a meeting summary, the conclusions and recommendations, the data center reports and proposals considered by the participants. (author)

Radiation biophysics

International Nuclear Information System (INIS)

Anon.

1979-01-01

Summaries of research projects conducted during 1978 and 1979 are presented. The overall thrust of the research is aimed at understanding the effects of radiation on organisms. Specific subject areas include: the effects of heavy-particle beam nuclear interactions in tissue on dosimetry; tracer studies with radioactive fragments of heavy-ion beams; the effects of heavy/ions on human kidney cells and Chinese hamster cells; the response of a rhabdomyosarcoma tumor system in rats to heavy-ion beams; the use of heavy charged particles in radiotherapy of human cancer; heavy-ion radiography; the biological effects of high magnetic fields; central nervous system neurotoxicity; and biophysical studies on cell membranes

Ninth plenary meeting of the International Working Group on Water Reactor Fuel Performance and Technology Vienna, 2-4 October 1989

International Nuclear Information System (INIS)

1990-03-01

The 9th Plenary Meeting of the International Working Group on Water Reactor Fuel Performance and Technology (IWGFPT) was held in Vienna from 2 to 4 October 1989. The meeting was attended by 24 participants from 18 Member States and one international organization. This publication is a summary report of this meeting. It contains review of the IWGFPT activities of the period since the 8th meeting. The representatives of the Member States presented information about National Programs and multilateral projects status with emphasis on new results. Summary of the discussion on schedule of IWGFPT activities for the period of 1990-91 is also published in this report. Refs, figs and tabs

From autopoiesis to neurophenomenology: Francisco Varela's exploration of the biophysics of being

Directory of Open Access Journals (Sweden)

DAVID RUDRAUF

2003-01-01

Full Text Available This paper reviews in detail Francisco Varela's work on subjectivity and consciousness in the biological sciences. His original approach to this "hard problem" presents a subjectivity that is radically intertwined with its biological and physical roots. It must be understood within the framework of his theory of a concrete, embodied dynamics, grounded in his general theory of autonomous systems. Through concepts and paradigms such as biological autonomy, embodiment and neurophenomenology, the article explores the multiple levels of circular causality assumed by Varela to play a fundamental role in the emergence of human experience. The concept of biological autonomy provides the necessary and sufficient conditions for characterizing biological life and identity as an emergent and circular self-producing process. Embodiment provides a systemic and dynamical framework for understanding how a cognitive -a mind- can arise in an organism in the midst of its operational cycles of internal regulation and ongoing sensorimotor coupling. Global subjective properties can emerge at different levels from the interactions of components and can reciprocally constrain local processes through an ongoing, recursive morphodynamics. Neurophenomenology is a supplementary step in the study of consciousness. Through a rigorous method, it advocates the careful examination of experience with first-person methodologies. It attempts to create heuristic mutual constraints between biophysical data and data produced by accounts of subjective experience. The aim is to explicitly ground the active and disciplined insight the subject has about his/her experience in a biophysical emergent process. Finally, we discuss Varela's essential contribution to our understanding of the generation of consciousness in the framework of what we call his "biophysics of being."

Minutes of the First International Editorial Board Meeting of Chinese Journal of Traumatology.

Science.gov (United States)

Peng, Yuan-Yuan; Tian, Y

2016-06-01

The First International Editorial Board Meeting of Chinese Journal of Traumatology was held in Guiyang, China on August 16, 2015. Totally 32 domestic and 20 foreign professors from America, Europe, Asia and Oceania attended the panel discussion about the future of this journal. Some experience from globally excellent journals was proposed.

Biophysics of Human Hair Structural, Nanomechanical, and Nanotribological Studies

CERN Document Server

Bhushan, Bharat

2010-01-01

This book presents the biophysics of hair. It deals with the structure of hair, its mechanical properties, the nanomechanical characterization, tensile deformation, tribological characterization, the thickness distribution and binding interactions on hair surface. Another important topic of the book is the health of hair, human hair and skin, hair care, cleaning and conditioning treatments and damaging processes. It is the first book on the biophysical properties of hair.

Ninth regular meeting of the International Working Group on Reliability of Reactor Pressure Components, Vienna, 18-20 October 1988

International Nuclear Information System (INIS)

1990-04-01

The 9th regular meeting of the International Working Group on Reliability of Pressure Components took place from 18-20 October 1988 at the Agency's Headquarters. The meeting was attended by 25 representatives from 19 Member States and International Organizations. The agenda of the meeting included overviews of the national activities in the field of pressure retaining components of PWRs, review of the past IWGRRPC activities and updating of the working plan for years 1989-1992. A great deal of attention was paid to the involvement of the IWGRRPC in the Agency's programme on nuclear power plant ageing and life extension. Members of the IWGRRPC reviewed the long term plan of the activities and proposed a provisional list and scope of the IAEA Specialists' Meetings planned for the period 1989-1992. Seventeen papers were presented at the meeting. A separate abstract was prepared for each of these papers. Refs, figs and tabs

Applications of synchrotron radiation in Biophysics

International Nuclear Information System (INIS)

Bemski, G.

1983-01-01

A short introduction to the generation of the synchrotron radiation is made. Following, the applications of such a radiation in biophysics with emphasis to the study of the hemoglobin molecule are presented. (L.C.) [pt

Proceedings of the international meeting on research and test reactor core conversions from HEU to LEU fuels

Energy Technology Data Exchange (ETDEWEB)

Travelli, A [Argonne National Laboratory, Argonne, IL (United States)

1983-09-01

Conversion of research and test reactor cores from the use of high enrichment uranium to the use of low enrichment uranium depends on the cooperation of many research organizations, reactor operators, and government agencies. At a technical level, it involves almost all aspects of the fuel cycle, including fuel development, testing, shipping and reprocessing; experiment performance; economics; and safety and licensing aspects. The reactors involved and the conversion activities are distributed among approximately 25 countries, making this a subject which is best dealt with on an international basis. To foster direct communication in this area, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at the Argonne National Laboratory, sponsored this meeting as the fifth of a series which began in 1978. The previous meetings were held at Argonne (International Meeting of Research Reactor Fuel Designers, Developers, and Fabricators, Argonne National Laboratory, Argonne, U.S.A., November 910, 1978), at Saclay (IAEA Consultants' Meeting on Research Reactor Core Conversions from HEU to LEU, Centre d'etudes Nucleaires de Saclay, Saclay, France, December 12-14, 1979), at Argonne (International Meeting on Development, Fabrication and Application of Reduced Enrichment Fuels for Research and Test Reactors, Argonne National Laboratory, Argonne, U.S.A., November 12-14, 1980) and at Juelich (Seminar on Research Reactor Operation and Use, Juelich Nuclear Research Center, Juelich, F.R.G., September 48, 1981). Proceedings from the two most recent previous meetings were published as ANL/RERTR/TM-3 (CONF-801144) and IAEA-SR-77. The spirit of this meeting differs slightly from that of the previous meetings. The advances which have been made and the growing maturity of the effort have caused a gradual shift of emphasis away from those topics which dominated the floor during the first meetings, such as fuel and methods development, and towards topics which concern more

Proceedings of the international meeting on research and test reactor core conversions from HEU to LEU fuels

International Nuclear Information System (INIS)

Travelli, A.

1983-09-01

Conversion of research and test reactor cores from the use of high enrichment uranium to the use of low enrichment uranium depends on the cooperation of many research organizations, reactor operators, and government agencies. At a technical level, it involves almost all aspects of the fuel cycle, including fuel development, testing, shipping and reprocessing; experiment performance; economics; and safety and licensing aspects. The reactors involved and the conversion activities are distributed among approximately 25 countries, making this a subject which is best dealt with on an international basis. To foster direct communication in this area, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at the Argonne National Laboratory, sponsored this meeting as the fifth of a series which began in 1978. The previous meetings were held at Argonne (International Meeting of Research Reactor Fuel Designers, Developers, and Fabricators, Argonne National Laboratory, Argonne, U.S.A., November 910, 1978), at Saclay (IAEA Consultants' Meeting on Research Reactor Core Conversions from HEU to LEU, Centre d'etudes Nucleaires de Saclay, Saclay, France, December 12-14, 1979), at Argonne (International Meeting on Development, Fabrication and Application of Reduced Enrichment Fuels for Research and Test Reactors, Argonne National Laboratory, Argonne, U.S.A., November 12-14, 1980) and at Juelich (Seminar on Research Reactor Operation and Use, Juelich Nuclear Research Center, Juelich, F.R.G., September 48, 1981). Proceedings from the two most recent previous meetings were published as ANL/RERTR/TM-3 (CONF-801144) and IAEA-SR-77. The spirit of this meeting differs slightly from that of the previous meetings. The advances which have been made and the growing maturity of the effort have caused a gradual shift of emphasis away from those topics which dominated the floor during the first meetings, such as fuel and methods development, and towards topics which concern more

Minutes of the 22nd meeting of the International Nuclear Data Committee

International Nuclear Information System (INIS)

Nichols, A.L.

1999-09-01

At the twenty-second meeting (held at IAEA Headquarters in Vienna, Austria, 11-14 May 1999), the International Nuclear Data Committee (INDC) formed four working groups: 1. Review of Nuclear Data Section (IAEA-NDS) Programme; 2. Technology Transfer and Training; 3. Nuclear Data Dissemination; 4. Review of Data Development. The detailed deliberations, conclusions and recommendations of each working group are given in this report

25 October 2017 - Meeting on a South-East European International Institute for Sustainable Technologies

CERN Multimedia

Ordan, Julien Marius

2017-01-01

Meeting on a South-East European International Institute for Sustainable Technologies at CERN, organised by the Ministry of Science of Montenegro, followed by a lunch hosted by CERN Director-General F. Gianotti and a site visit to CMS counting room and S'Cool LAB.

76 FR 56865 - U.S. Department of State Advisory Committee on Private International Law (ACPIL): Public Meeting...

Science.gov (United States)

2011-09-14

... International Law (ACPIL): Public Meeting on Electronic Commerce The Department of State, Office of Legal... future work of Working Group IV (international electronic commerce) of the United Nations Commission on... electronic commerce. The report of the Forty-fourth session of UNCITRAL describes the future work of Group IV...

Full text publication rates of studies presented at an international emergency medicine scientific meeting.

Science.gov (United States)

Chan, Jannet W M; Graham, Colin A

2011-09-01

The publication rate of full text papers following an abstract presentation at a medical conference is variable, and few studies have examined the situation with respect to international emergency medicine conferences. This retrospective study aimed to identify the publication rate of abstracts presented at the 2006 International Conference on Emergency Medicine (ICEM) held in Halifax, Canada. The full text publication rate was 33.2%, similar to previous emergency medicine meetings. English language barriers may play a role in the low publication rate seen.

Meeting the International Health Regulations (2005) surveillance core capacity requirements at the subnational level in Europe

DEFF Research Database (Denmark)

Ziemann, Alexandra; Rosenkötter, Nicole; Riesgo, Luis Garcia-Castrillo

2015-01-01

BACKGROUND: The revised World Health Organization's International Health Regulations (2005) request a timely and all-hazard approach towards surveillance, especially at the subnational level. We discuss three questions of syndromic surveillance application in the European context for assessing...... public health emergencies of international concern: (i) can syndromic surveillance support countries, especially the subnational level, to meet the International Health Regulations (2005) core surveillance capacity requirements, (ii) are European syndromic surveillance systems comparable to enable cross...... effect of different types of public health emergencies in a timely manner as required by the International Health Regulations (2005)....

Across Space and Time: Social Responses to Large-Scale Biophysical Systems

Science.gov (United States)

Macmynowski, Dena P.

2007-06-01

The conceptual rubric of ecosystem management has been widely discussed and deliberated in conservation biology, environmental policy, and land/resource management. In this paper, I argue that two critical aspects of the ecosystem management concept require greater attention in policy and practice. First, although emphasis has been placed on the “space” of systems, the “time”—or rates of change—associated with biophysical and social systems has received much less consideration. Second, discussions of ecosystem management have often neglected the temporal disconnects between changes in biophysical systems and the response of social systems to management issues and challenges. The empirical basis of these points is a case study of the “Crown of the Continent Ecosystem,” an international transboundary area of the Rocky Mountains that surrounds Glacier National Park (USA) and Waterton Lakes National Park (Canada). This project assessed the experiences and perspectives of 1) middle- and upper-level government managers responsible for interjurisdictional cooperation, and 2) environmental nongovernment organizations with an international focus. I identify and describe 10 key challenges to increasing the extent and intensity of transboundary cooperation in land/resource management policy and practice. These issues are discussed in terms of their political, institutional, cultural, information-based, and perceptual elements. Analytic techniques include a combination of environmental history, semistructured interviews with 48 actors, and text analysis in a systematic qualitative framework. The central conclusion of this work is that the rates of response of human social systems must be better integrated with the rates of ecological change. This challenge is equal to or greater than the well-recognized need to adapt the spatial scale of human institutions to large-scale ecosystem processes and transboundary wildlife.

Unraveling biophysical interactions of radiation pneumonitis in non-small-cell lung cancer via Bayesian network analysis.

Science.gov (United States)

Luo, Yi; El Naqa, Issam; McShan, Daniel L; Ray, Dipankar; Lohse, Ines; Matuszak, Martha M; Owen, Dawn; Jolly, Shruti; Lawrence, Theodore S; Kong, Feng-Ming Spring; Ten Haken, Randall K

2017-04-01

In non-small-cell lung cancer radiotherapy, radiation pneumonitis≥grade 2 (RP2) depends on patients' dosimetric, clinical, biological and genomic characteristics. We developed a Bayesian network (BN) approach to explore its potential for interpreting biophysical signaling pathways influencing RP2 from a heterogeneous dataset including single nucleotide polymorphisms, micro RNAs, cytokines, clinical data, and radiation treatment plans before and during the course of radiotherapy. Model building utilized 79 patients (21 with RP2) with complete data, and model testing used 50 additional patients with incomplete data. A developed large-scale Markov blanket approach selected relevant predictors. Resampling by k-fold cross-validation determined the optimal BN structure. Area under the receiver-operating characteristics curve (AUC) measured performance. Pre- and during-treatment BNs identified biophysical signaling pathways from the patients' relevant variables to RP2 risk. Internal cross-validation for the pre-BN yielded an AUC=0.82 which improved to 0.87 by incorporating during treatment changes. In the testing dataset, the pre- and during AUCs were 0.78 and 0.82, respectively. Our developed BN approach successfully handled a high number of heterogeneous variables in a small dataset, demonstrating potential for unraveling relevant biophysical features that could enhance prediction of RP2, although the current observations would require further independent validation. Copyright © 2017 Elsevier B.V. All rights reserved.

Co-ordination of the International Network of Nuclear Structure and Decay Data Evaluators; Summary Report of an IAEA Technical Meeting

Energy Technology Data Exchange (ETDEWEB)

Abriola, D.; Tuli, J.

2009-03-23

The IAEA Nuclear Data Section convened the 18th meeting of the International Network of Nuclear Structure and Decay Data Evaluators at the IAEA Headquarters, Vienna, 23 to 27 March 2009. This meeting was attended by 22 scientists from 14 Member States, plus IAEA staff, concerned with the compilation, evaluation and dissemination of nuclear structure and decay data. A summary of the meeting, recommendations/conclusions, data centre reports, and various proposals considered, modified and agreed by the participants are contained within this document. The International Network of Nuclear Structure and Decay Data (NSDD) Evaluators holds biennial meetings under the auspices of the IAEA, and consists of evaluation groups and data service centres in several countries. This network has the objective of providing up-to-date nuclear structure and decay data for all known nuclides by evaluating all existing experimental data. Data resulting from this international evaluation collaboration is included in the Evaluated Nuclear Structure Data File (ENSDF) and published in the journals Nuclear Physics A and Nuclear Data Sheets (NDS).

Biophysical aspects of photodynamic therapy.

Science.gov (United States)

Juzeniene, Asta; Nielsen, Kristian Pagh; Moan, Johan

2006-01-01

Over the last three decades photodynamic therapy (PDT) has been developed to a useful clinical tool, a viable alternative in the treatment of cancer and other diseases. Several disciplines have contributed to this development: chemistry in the development of new photosensitizing agents, biology in the elucidation of cellular processes involved in PDT, pharmacology and physiology in identifying the mechanisms of distribution of photosensitizers in an organism, and, last but not least, physics in the development of better light sources, dosimetric concepts and construction of imaging devices, optical sensors and spectroscopic methods for determining sensitizer concentrations in different tissues. Physics and biophysics have also helped to focus on the role of pH for sensitizer accumulation, dose rate effects, oxygen depletion, temperature, and optical penetration of light of different wavelengths into various types of tissue. These are all important parameters for optimally effective PDT. The present review will give a brief, physically based, overview of PDT and then discuss some of the main biophysical aspects of this therapeutic modality.

Use of Convexity in Ostomy Care: Results of an International Consensus Meeting.

Science.gov (United States)

Hoeflok, Jo; Salvadalena, Ginger; Pridham, Sue; Droste, Werner; McNichol, Laurie; Gray, Mikel

Ostomy skin barriers that incorporate a convexity feature have been available in the marketplace for decades, but limited resources are available to guide clinicians in selection and use of convex products. Given the widespread use of convexity, and the need to provide practical guidelines for appropriate use of pouching systems with convex features, an international consensus panel was convened to provide consensus-based guidance for this aspect of ostomy practice. Panelists were provided with a summary of relevant literature in advance of the meeting; these articles were used to generate and reach consensus on 26 statements during a 1-day meeting. Consensus was achieved when 80% of panelists agreed on a statement using an anonymous electronic response system. The 26 statements provide guidance for convex product characteristics, patient assessment, convexity use, and outcomes.

PREFACE: 2nd International Meeting for Researchers in Materials and Plasma Technology

Science.gov (United States)

Niño, Ely Dannier V.

2013-11-01

These proceedings present the written contributions of the participants of the 2nd International Meeting for Researchers in Materials and Plasma Technology, 2nd IMRMPT, which was held from February 27 to March 2, 2013 at the Pontificia Bolivariana Bucaramanga-UPB and Santander and Industrial - UIS Universities, Bucaramanga, Colombia, organized by research groups from GINTEP-UPB, FITEK-UIS. The IMRMPT, was the second version of biennial meetings that began in 2011. The three-day scientific program of the 2nd IMRMPT consisted in 14 Magisterial Conferences, 42 Oral Presentations and 48 Poster Presentations, with the participation of undergraduate and graduate students, professors, researchers and entrepreneurs from Colombia, Russia, France, Venezuela, Brazil, Uruguay, Argentina, Peru, Mexico, United States, among others. Moreover, the objective of IMRMPT was to bring together national and international researchers in order to establish scientific cooperation in the field of materials science and plasma technology; introduce new techniques of surface treatment of materials to improve properties of metals in terms of the deterioration due to corrosion, hydrogen embrittlement, abrasion, hardness, among others; and establish cooperation agreements between universities and industry. The topics covered in the 2nd IMRMPT include New Materials, Surface Physics, Laser and Hybrid Processes, Characterization of Materials, Thin Films and Nanomaterials, Surface Hardening Processes, Wear and Corrosion / Oxidation, Modeling, Simulation and Diagnostics, Plasma Applications and Technologies, Biomedical Coatings and Surface Treatments, Non Destructive Evaluation and Online Process Control, Surface Modification (Ion Implantation, Ion Nitriding, PVD, CVD). The editors hope that those interested in the are of materials science and plasma technology, enjoy the reading that reflect a wide range of topics. It is a pleasure to thank the sponsors and all the participants and contributors for

Building biophysics in mid-century China: the University of Science and Technology of China.

Science.gov (United States)

Luk, Yi Lai Christine

2015-01-01

Biophysics has been either an independent discipline or an element of another discipline in the United States, but it has always been recognized as a stand-alone discipline in the People's Republic of China (PRC) since 1949. To inquire into this apparent divergence, this paper investigates the formational history of biophysics in China by examining the early institutional history of one of the best-known and prestigious science and technology universities in the PRC, the University of Science and Technology of China (USTC). By showing how the university and its biophysics program co-evolved with national priorities from the school's founding in 1958 to the eve of the Cultural Revolution in 1966, the purpose of this paper is to assess the development of a scientific discipline in the context of national demands and institutional politics. Specific materials for analysis include the school's admission policies, curricula, students' dissertations, and research program. To further contextualize the institutional setting of Chinese biophysics, this paper begins with a general history of proto-biophysical institutions in China during the Nationalist-Communist transitional years. This paper could be of interest to historians wanting to know more about the origin of the biophysics profession in China, and in particular how research areas that constitute biophysics changed in tandem with socio-political contingencies.

Second meeting of the International Working Group on Advanced Technologies for Water Cooled Reactors, Helsinki, 6-9 June 1988

International Nuclear Information System (INIS)

1989-05-01

The Second Meeting of the IAEA International Working Group on Advanced Technologies for Water Cooled Reactors (IWGATWR) was held in Helsinki, Finland, from 6-9 June 1988. The Summary Report (Part II) contains the papers which review the national programmes since the first meeting of IWGATWR in May 1987 in the field of Advanced Technologies for Water Cooled Reactors and other presentations at the Meeting. A separate abstract was prepared for each of these 12 papers presented at the meeting. Figs and tabs

Introducing "biophysical redundancy": the global status and past evolution of unused water, land and productivity resources for food production

Science.gov (United States)

Fader, Marianela

2017-04-01

Countries have different resilience to sudden and long-term changes in food demand and supply. An important part of this resilience is the degree of biophysical redundancy, defined as the potential food production of 'spare land', available water resources (i.e., not already used for human activities), as well as production increases through yield gap closure on cultivated areas and potential agricultural areas. The presentation will show the results of a recently published paper1 on the evolution of biophysical redundancy for agricultural production at country level, from 1992 to 2012. Results indicate that in 2012, the biophysical redundancy of 75 (48) countries, mainly in North Africa, Western Europe, the Middle East and Asia, was insufficient to produce the caloric nutritional needs for at least 50% (25%) of their population during a year. Biophysical redundancy has decreased in the last two decades in 102 out of 155 countries, 11 of these went from high to limited redundancy, and nine of these from limited to very low redundancy. Although the variability of the drivers of change across different countries is high, improvements in yield and population growth have a clear impact on the decreases of redundancy towards the very low redundancy category. We took a more detailed look at countries classified as 'Low Income Economies (LIEs)' since they are particularly vulnerable to domestic or external food supply changes, due to their limited capacity to offset for food supply decreases with higher purchasing power on the international market. Currently, nine LIEs have limited or very low biophysical redundancy. Many of these showed a decrease in redundancy over the last two decades, which is not always linked with improvements in per capita food availability.

Minutes of the meeting of the international program committee

Science.gov (United States)

2012-12-01

The meeting of the International Program Committee occurred on 5 June 2012. The agenda consisted of the following items: - Information on conference participants, contributions and grants - Information on the financial support received by the conference - Committee membership - Organizers of the next two meeting of the ICSLS Conference participants and contributions There were about 100 registered participants for the ICSLS. They presented more than 100 contributions, namely, 19 invited talks, 20 oral contributions and more than 61 contributed papers. It was noted that only very few participants came from North America. Reasons quoted were finacial problems of laboratories and overlapping of several conferences. Finacial support received The conference received grants from St. Petersburg University, the Russian Foundation for Basic Research, and the non-profit Dynasty Foundation. About 40% of the budget was collected in the form of registration fees. Discounted fees and fee waives were provided for 40 participants. Committee membership The Committee instructed Professor A Devdariani to contact the absent members who had missed two successive conferences and ask them whether they intended to prolong their membership on the Committee, and inform other Committee members accordingly. Organizers of the next meetings of the ICSLS The 20th ICSLS held in St. John's, Newfoundland, Canada decided to hold the 22nd ICSLS at the University of Tennessee. The event will be organized by Christian Parriger. All issues regarding the next conference were discussed including budget, travel, conference site, accommodation, and proceedings. Torun, Poland was proposed for the 23d ICSLS by Roman Ciurylo. Roland Stamm proposed the Aix-Marseille University as a backup to the first proposal.

Fifth joint meeting of the American Urological Association and the Japanese Urological Association International Affiliate Society Meeting at the 105th Annual Meeting of the American Urological Association.

Science.gov (United States)

Myers, Robert P; Seki, Narihito; Gotoh, Momokazu; Chai, Toby C; Kaplan, Steven A; Inoue, Keiji; Trachtenberg, John; Kikuchi, Eiji; Nishiyama, Hiroyuki; Chang, Sam S; Lee, Cheryl; Muto, Satoru; Ito, Kazuto; Andriole, Gerald L; Eto, Masatoshi; Sumitomo, Makoto; Kamba, Tomomi; Wood, Chrsitopher G; Margulis, Vitaly; Naito, Seiji; Egawa, Shin

2010-08-01

We are heartily grateful for the warm support of all of the people concerned, including the moderators and panelists of both societies for giving us the opportunity to hold the 5(th) American Urological Association/Japanese Urological Association (AUA/JUA) International Affiliate Society Meeting, held once again at the 105th Annual Meeting of the American Urological Association (29 May-3 June 2010, San Francisco, California, USA). The year of 2010 is a memorable one, being the start of reciprocal collaborations between the AUA and the JUA. The JUA, in collaboration with the AUA, is promoting an academic exchange program whereby outstanding and promising Japanese and American junior faculty members will be given the opportunity to work in the USA and Japan for 1 month. The program not only allows the sharing of knowledge and experience, but also is designed to foster a closer alliance between the AUA and JUA, and assists in identifying future leaders within both organizations. The AUA and JUA will have an exhibit booth at each other's annual meeting, promoting our new joint activities. Both the JUA and AUA will organize educational courses in Hawaii in 2011. With all of these activities, the JUA hopes it will provide greater opportunities for young Japanese urologists to participate in educational projects in the USA. We would like to thank Professor Anton J. Bueschen, President of AUA, Professor Robert C Flanigan, Secretary General of AUA and the staff of the AUA and JUA for supporting our program. At the same time, we need the support of all the members and their valuable suggestions. We look forward to further participation of AUA members to this meeting. Seiji Naito md, President of JUA Shin Egawa md, Chairman of the International Committee of JUA.

Biophysical aspects of cancer - Electromagnetic mechanism

Czech Academy of Sciences Publication Activity Database

Pokorný, Jiří; Hašek, Jiří; Vaniš, Jan; Jelínek, František

2008-01-01

Roč. 46, č. 5 (2008), s. 310-321 ISSN 0019-5189 Institutional research plan: CEZ:AV0Z20670512; CEZ:AV0Z50200510 Keywords : Electromagnetic Fields * Biophysics * Cancer Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 0.599, year: 2008

Studies of land-cover, land-use, and biophysical properties of vegetation in the Large Scale Biosphere Atmosphere experiment in Amazonia.

Science.gov (United States)

Dar A. Robertsa; Michael Keller; Joao Vianei Soares

2003-01-01

We summarize early research on land-cover, land-use, and biophysical properties of vegetation from the Large Scale Biosphere Atmosphere (LBA) experiment in Amazoˆnia. LBA is an international research program developed to evaluate regional function and to determine how land-use and climate modify biological, chemical and physical processes there. Remote sensing has...

Report of the 86. meeting of the International bureau of weights and measurements, September 1997

International Nuclear Information System (INIS)

1998-01-01

The task of the BIPM is to ensure world-wide unification of physical measurements; its function is thus to: establish fundamental standards and scales for the measurement of the principal physical quantities and maintain the international standards; carry out comparisons of national and international standards; ensure the coordination of corresponding measurement techniques; carry out and coordinate measurements of the fundamental physical constants relevant to these activities. The BIPM operates under the exclusive supervision of the Comite International des Poids et Mesures (CIPM) which itself comes under the authority of the Conference Generale des Poids et Mesures (CGPM) and reports to it on the work accomplished by the BIPM. Delegates from all Member States of the Metre Convention attend the General Conference which, at present, meets every four years. The function of these meetings is to: discuss and initiate the arrangements required to ensure the propagation and improvement of the International System of Units (SI), which is the modern form of the metric system; confirm the results of new fundamental metrological determinations and various scientific resolutions of international scope; take all major decisions concerning the finance, organization and development of the BIPM. The CIPM has eighteen members each from a different State: at present, it meets every year. The officers of this committee present an annual report on the administrative and financial position of the BIPM to the Governments of the Member States of the Metre Convention. The principal task of the CIPM is to ensure world-wide uniformity in units of measurement. It does this by direct action or by submitting proposals to the CGPM. The activities of the BIPM, which in the beginning were limited to measurements of length and mass, and to metrological studies in relation to these quantities, have been extended to standards of measurement of electricity (1927), photometry and radiometry (1937

The Berlin International Consensus Meeting on Concussion in Sport.

Science.gov (United States)

Davis, Gavin A; Ellenbogen, Richard G; Bailes, Julian; Cantu, Robert C; Johnston, Karen M; Manley, Geoffrey T; Nagahiro, Shinji; Sills, Allen; Tator, Charles H; McCrory, Paul

2018-02-01

The Fifth International Conference on Concussion in Sport was held in Berlin in October 2016. A series of 12 questions and subquestions was developed and the expert panel members were required to perform a systematic review to answer each question. Following presentation at the Berlin meeting of the systematic review, poster abstracts and audience discussion, the summary Consensus Statement was produced. Further, a series of tools for the management of sport-related concussion was developed, including the Sport Concussion Assessment Tool Fifth edition (SCAT5), the Child SCAT5, and the Concussion Recognition Tool Fifth edition. This paper elaborates on this process, the outcomes, and explores the implications for neurosurgeons in the management of sport-related concussion. Copyright © 2017 by the Congress of Neurological Surgeons.

JPRS Report, Science & Technology, Japan, International Society of Electrochemistry Meeting (40th) Held in Kyoto on 17-22 Sep 89

National Research Council Canada - National Science Library

1990-01-01

Selected "extended abstracts" presented at the 40th International Society of Electrochemistry Meeting held 17-22 Sep 89 in Kyoto, sponsored by the International Union of Pure and Applied Chemistry (IUPAC...

40 CFR 60.4231 - What emission standards must I meet if I am a manufacturer of stationary SI internal combustion...

Science.gov (United States)

2010-07-01

... I am a manufacturer of stationary SI internal combustion engines or equipment containing such... Stationary Spark Ignition Internal Combustion Engines Emission Standards for Manufacturers § 60.4231 What emission standards must I meet if I am a manufacturer of stationary SI internal combustion engines or...

A dataset mapping the potential biophysical effects of vegetation cover change

Science.gov (United States)

Duveiller, Gregory; Hooker, Josh; Cescatti, Alessandro

2018-02-01

Changing the vegetation cover of the Earth has impacts on the biophysical properties of the surface and ultimately on the local climate. Depending on the specific type of vegetation change and on the background climate, the resulting competing biophysical processes can have a net warming or cooling effect, which can further vary both spatially and seasonally. Due to uncertain climate impacts and the lack of robust observations, biophysical effects are not yet considered in land-based climate policies. Here we present a dataset based on satellite remote sensing observations that provides the potential changes i) of the full surface energy balance, ii) at global scale, and iii) for multiple vegetation transitions, as would now be required for the comprehensive evaluation of land based mitigation plans. We anticipate that this dataset will provide valuable information to benchmark Earth system models, to assess future scenarios of land cover change and to develop the monitoring, reporting and verification guidelines required for the implementation of mitigation plans that account for biophysical land processes.

Neutrons in Biology. A satellite meeting of the IUPAB/EBSA biophysics congress

Energy Technology Data Exchange (ETDEWEB)

Koji, Yoshida; Longeville, St.; Motomu, Tanaka; Blackledge, M.; Ebel, Ch.; Cooper, J.B.; Curmi, P.; Ferrand, M.; Gutberlet, T.; Huang, Huey Hang; Haub, T.; Mitsuhiro, Hirai; Geoff, Kneale; Langan, P.; Masahisa, Wada; Junji, Sugiyama; Yoshiharu, Nishiyama; Chanzy, H.; Leckband, D.; Meilleur, F.; Nawroth, Th.; Paciaroni, A.; Parak, F.; Gaede, H.C.; Soubias, O.; Luckett, K.M.; Polozov, I.V.; Wong, K.K.Y.; Yeliseev, A.A.; Gawrisch, K.; Deme, B.; Marchal, D.; Hanson, L.; Podjarny, A.; Mitschler, A.; Hazemann, I.; Blakeley, M.; Dauvergne, M.T.; Meilleur, F.; Budayova-Spano, M.; Van Zandt, M.; Ginell, S.; Joachimiak, A.; Myles, D.; Timmins, P.A.; Pebay-Peyroula, E; Welte, W.; Prince, S.M.; Howard, T.D.; Myles, D.A.A.; Wilkinson, C.; Papiz, M.Z.; Freer, A.A.; Cogdell, R.J.; Isaacs, N.W.; Papiz, M.Z.; Prince, S.M.; Howard, T.D.; Cogdell, R.J.; Isaacs, N.W.; Rheinstaedter, M.; Sapede, D.; Svergun, D.; Tarek, M.; Tehei, M.; Trewhella, J.; Watts, A.; Zaccai, G.J

2005-07-01

This meeting focussed on the study of the structure and dynamics of biological molecules, with particular emphasis on neutron and complementary methods as well as related enabling technologies. The program covered biological problems that are being addressed by neutron scattering and those where there is the potential to do so in the future. This document provides the abstracts of the different presentations. (A.L.B.)

Neutrons in Biology. A satellite meeting of the IUPAB/EBSA biophysics congress

International Nuclear Information System (INIS)

Koji, Yoshida; Longeville, St.; Motomu, Tanaka; Blackledge, M.; Ebel, Ch.; Cooper, J.B.; Curmi, P.; Ferrand, M.; Gutberlet, T.; Huang, Huey Hang; Haub, T.; Mitsuhiro, Hirai; Geoff, Kneale; Langan, P.; Masahisa, Wada; Junji, Sugiyama; Yoshiharu, Nishiyama; Chanzy, H.; Leckband, D.; Meilleur, F.; Nawroth, Th.; Paciaroni, A.; Parak, F.; Gaede, H.C.; Soubias, O.; Luckett, K.M.; Polozov, I.V.; Wong, K.K.Y.; Yeliseev, A.A.; Gawrisch, K.; Deme, B.; Marchal, D.; Hanson, L.; Podjarny, A.; Mitschler, A.; Hazemann, I.; Blakeley, M.; Dauvergne, M.T.; Meilleur, F.; Budayova-Spano, M.; Van Zandt, M.; Ginell, S.; Joachimiak, A.; Myles, D.; Timmins, P.A.; Pebay-Peyroula, E; Welte, W.; Prince, S.M.; Howard, T.D.; Myles, D.A.A.; Wilkinson, C.; Papiz, M.Z.; Freer, A.A.; Cogdell, R.J.; Isaacs, N.W.; Papiz, M.Z.; Prince, S.M.; Howard, T.D.; Cogdell, R.J.; Isaacs, N.W.; Rheinstaedter, M.; Sapede, D.; Svergun, D.; Tarek, M.; Tehei, M.; Trewhella, J.; Watts, A.; Zaccai, G.J.

2005-01-01

This meeting focussed on the study of the structure and dynamics of biological molecules, with particular emphasis on neutron and complementary methods as well as related enabling technologies. The program covered biological problems that are being addressed by neutron scattering and those where there is the potential to do so in the future. This document provides the abstracts of the different presentations. (A.L.B.)

International climate change policy: background and significance of upcoming COP17 meeting for South Africa

CSIR Research Space (South Africa)

Thambiran, Tirusha

2011-09-01

Full Text Available COP17 is primarily a meeting about climate change and what can be done internationally to mitigate climate change. The overarching mitigation goal is to develop a legally binding agreement to control and limit the amount of GHGs that countries would...

A mathematical approach to protein biophysics

CERN Document Server

Scott, L Ridgway

2017-01-01

This book explores quantitative aspects of protein biophysics and attempts to delineate certain rules of molecular behavior that make atomic scale objects behave in a digital way.  This book will help readers to understand how certain biological systems involving proteins function as digital information systems despite the fact that underlying processes are analog in nature. The in-depth explanation of proteins from a quantitative point of view and the variety of level of exercises (including physical experiments) at the end of each chapter will appeal to graduate and senior undergraduate students in mathematics, computer science, mechanical engineering, and physics, wanting to learn about the biophysics of proteins.  L. Ridgway Scott has been Professor of Computer Science and of Mathematics at the University of Chicago since 1998, and the Louis Block Professor since 2001.  He obtained a B.S. degree (Magna Cum Laude) from Tulane University in 1969 and a PhD degree in Mathematics from the Massachusetts Ins...

Institute of Biochemistry and Biophysics. Research Report 1996-1997

International Nuclear Information System (INIS)

1998-01-01

Scientific interests of the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences have evolved from classical biochemistry, biophysics and physiological chemistry to up-to-date molecular biology. Research interests are focussed on replication, mutagenesis and repair of DNA; regulation of gene expression at various levels; biosynthesis and post-translational modifications of proteins; gene sequencing and functional analysis of open reading frames; structure, function and regulation of enzymes; conformation of proteins and peptides; modelling of structures and prediction of functions of proteins; mechanisms of electron transfer in polypeptides

Institute of Biochemistry and Biophysics. Research Report 1996-1997

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-07-01

Scientific interests of the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences have evolved from classical biochemistry, biophysics and physiological chemistry to up-to-date molecular biology. Research interests are focussed on replication, mutagenesis and repair of DNA; regulation of gene expression at various levels; biosynthesis and post-translational modifications of proteins; gene sequencing and functional analysis of open reading frames; structure, function and regulation of enzymes; conformation of proteins and peptides; modelling of structures and prediction of functions of proteins; mechanisms of electron transfer in polypeptides.

Biophysical Influence of Airborne Carbon Nanomaterials on Natural Pulmonary Surfactant

OpenAIRE

Valle, Russell P.; Wu, Tony; Zuo, Yi Y.

2015-01-01

Inhalation of nanoparticles (NP), including lightweight airborne carbonaceous nanomaterials (CNM), poses a direct and systemic health threat to those who handle them. Inhaled NP penetrate deep pulmonary structures in which they first interact with the pulmonary surfactant (PS) lining at the alveolar air–water interface. In spite of many research efforts, there is a gap of knowledge between in vitro biophysical study and in vivo inhalation toxicology since all existing biophysical models handl...

GENERAL INFORMATION MEETING on the European Co-operative Association of International Civil Servants (AMFIE)

CERN Multimedia

HR Department

2010-01-01

Wednesday 29 September 2010 at 11h (160/1-009) Mr. Dimitri ARGYROPOULOS, Chairman of AMFIE's*) Board of Directors and Mrs. Janine RIVALS, Member of AMFIE's Board of Directors, will make a general presentation on AMFIE's personal financial services and how they may benefit international civil servants. They will also focus on the particular financial challenges faced by expatriate civil servants and on the solutions AMFIE can offer. The presentation will be followed by a question and answer session. Private consultations - 9:00 to 11:00 and 14:00 to 17:30 (5/1-030) Participants who wish to meet AMFIE's representatives for one-to-one private consultations are invited to contact directly Mrs. Janine Rivals (+33/1 45 35 70 79, GSM +33/6 63 58 36 62 or jr@amfie.org) or AMFIE's Secretariat in Luxembourg (+352/42 36 61-1 or amfie@amfie.org). A dedicated form will also be available for this purpose in the meeting room during the presentation. *)\tAMFIE is a cooperative society open exclusively to international ...

Research Institute for Medical Biophysics

International Nuclear Information System (INIS)

Wynchank, S.

1989-01-01

The effects of ionising and non-ionising radiation on rodent tumours and normal tissue were studied in terms of cellular repair and the relevant biochemical and biophysical changes following radiation. Rodent tumours investigated in vivo were the CaNT adenocarcinoma and a chemically induced transplantable rhabdomyosarcoma. Radiations used were 100KVp of X-Rays, neutron beams, various magnetic fields, and microwave radiation of 2450MHz. The biochemical parameters measured were, inter alia, levels of adenosine-5'-triphoshate (ATP) and the specific activity of hexokinase (HK). Metabolic changes in ATP levels and the activity of HK were observed in tumour and normal tissues following ionising and non-ionising radiation in normoxia and hypoxia. The observation that the effect of radiation and chemotherapeutic treatment of some tumours may be size dependent can possibly now be explained by the variation of ATP content with tumour size. The enhanced tumour HK specific activity implies increased metabolism, possibly a consequence of cellular requirements to maintain homeostasis during repair processes. Other research projects of the Research Institute for Medical Biophysics involved, inter alia, gastroesophageal scintigraphies to evaluate the results of new forms of therapy. 1 ill

Eighth meeting of the International Working Group on Gas-Cooled Reactors, Vienna, 30 January - 1 February 1989. Summary report. Part 1

International Nuclear Information System (INIS)

1989-12-01

The Eighth Meeting of the IAEA International Working Group on Gas-Cooled Reactors was held in Vienna, Austria, from 30 January - 1 February, 1989. The Summary Report (Part I) contains the Minutes of the Meeting

Simulation in International Studies

Science.gov (United States)

Boyer, Mark A.

2011-01-01

Social scientists have long worked to replicate real-world phenomena in their research and teaching environments. Unlike our biophysical science colleagues, we are faced with an area of study that is not governed by the laws of physics and other more predictable relationships. As a result, social scientists, and international studies scholars more…

Management of water hyacinth: Final meeting and international conference. Working paper submitted by the Regional Coordinator

International Nuclear Information System (INIS)

1981-01-01

Full text: Final Meeting. This meeting will essentially make a terminal review of the project and register final records of work done on the various aspects, such as: - biology of the plant; - biological control; - biogas; - wastewater treatment; - papers and boards; - integrated systems, etc. We should have at the meeting a complete account of the work done in the project under each of the above headings. For example, under 'biogas' we should prepare one consolidated account of work carried out in all the three participating countries rather than individual country reports. Likewise on 'papers and boards', and the other items. To enable preparation of reports in this form there should naturally be prior consultations and contacts among the concerned investigators by correspondence and, if necessary, personal visits. These reports will then be edited and compiled by the Regional Coordinator in the form of a book or monograph on the Management of Water Hyacinth project as a whole. Contributors to chapters will be cited. International Conference. Independent of the consolidated reports, national coordinators may prepare papers for presentation at the proposed international conference. These papers could be prepared m the usual form and style for publication in international scientific journals. Although several papers could be prepared out of work done by us, we may consider the desirability of limiting the number, in order to give adequate opportunities for the other invited participants to the conference. There would be no bar on publication of these scientific papers after the conference in appropriate journals irrespective of whether a separate volume on proceedings of the conference is brought out or not. India would be happy to host the terminal review meeting to be followed by the conference. The likely period would be last week of January to first week in February, 1983. (author)

Biophysics of Hair Cell Sensory Systems

NARCIS (Netherlands)

Duifhuis, Hendrikus; Horst, Johannes; van Dijk, Pim; van Netten, Sietse

1993-01-01

The last decade revealed to auditory researchers that hair cells can not only detect and process mechanical energy, but are also able to produce it. Thanks to the active hair cell, ears can produce otoacoustic emissions. This book gives the newest insights into the biophysics and physiology of

Replacing natural wetlands with stormwater management facilities: Biophysical and perceived social values.

Science.gov (United States)

Rooney, R C; Foote, L; Krogman, N; Pattison, J K; Wilson, M J; Bayley, S E

2015-04-15

Urban expansion replaces wetlands of natural origin with artificial stormwater management facilities. The literature suggests that efforts to mimic natural wetlands in the design of stormwater facilities can expand the provision of ecosystem services. Policy developments seek to capitalize on these improvements, encouraging developers to build stormwater wetlands in place of stormwater ponds; however, few have compared the biophysical values and social perceptions of these created wetlands to those of the natural wetlands they are replacing. We compared four types of wetlands: natural references sites, natural wetlands impacted by agriculture, created stormwater wetlands, and created stormwater ponds. We anticipated that they would exhibit a gradient in biodiversity, ecological integrity, chemical and hydrologic stress. We further anticipated that perceived values would mirror measured biophysical values. We found higher biophysical values associated with wetlands of natural origin (both reference and agriculturally impacted). The biophysical values of stormwater wetlands and stormwater ponds were lower and indistinguishable from one another. The perceived wetland values assessed by the public differed from the observed biophysical values. This has important policy implications, as the public are not likely to perceive the loss of values associated with the replacement of natural wetlands with created stormwater management facilities. We conclude that 1) agriculturally impacted wetlands provide biophysical values equivalent to those of natural wetlands, meaning that land use alone is not a great predictor of wetland value; 2) stormwater wetlands are not a substantive improvement over stormwater ponds, relative to wetlands of natural origin; 3) stormwater wetlands are poor mimics of natural wetlands, likely due to fundamental distinctions in terms of basin morphology, temporal variation in hydrology, ground water connectivity, and landscape position; 4) these

Proceedings of the 1994 international meeting on reduced enrichment for research and test reactors

International Nuclear Information System (INIS)

1997-08-01

This meeting brought together participants in the international effort to minimize and eventually eliminate the use of highly enriched uranium in civilian nuclear programs. Papers cover the following topics: National programs; fuel cycle; nuclear fuels; analyses; advanced reactors; and reactor conversions. Selected papers have been indexed separately for inclusion to the Energy Science and Technology Database

Proceedings of the 1994 international meeting on reduced enrichment for research and test reactors

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-08-01

This meeting brought together participants in the international effort to minimize and eventually eliminate the use of highly enriched uranium in civilian nuclear programs. Papers cover the following topics: National programs; fuel cycle; nuclear fuels; analyses; advanced reactors; and reactor conversions. Selected papers have been indexed separately for inclusion to the Energy Science and Technology Database.

International Working Group on Fast Reactors Eight Annual Meeting, Vienna, Austria, 15-18 April 1975. Summary Report. Part II

International Nuclear Information System (INIS)

1975-07-01

The Eighth Annual Meeting of the IAEA International Working Group on Past Reactors was held at the IAEA Headquarters in Vienna, Austria, from 15 to 18 April 1975. The Summary Report (Part I) contains the Minutes of the Meeting. The Summary Report (Part II) contains the papers which review the national programmes in the field of LMPBR’s and other presentations at the Meeting. The Summary Report (Part III) contains the discussions on the review of the national programmes

Climate Change Effects on Agriculture: Economic Responses to Biophysical Shocks

Science.gov (United States)

Nelson, Gerald C.; Valin, Hugo; Sands, Ronald D.; Havlik, Petr; Ahammad, Helal; Deryng, Delphine; Elliott, Joshua; Fujimori, Shinichiro; Hasegawa, Tomoko; Heyhoe, Edwina

2014-01-01

Agricultural production is sensitive to weather and thus directly affected by climate change. Plausible estimates of these climate change impacts require combined use of climate, crop, and economic models. Results from previous studies vary substantially due to differences in models, scenarios, and data. This paper is part of a collective effort to systematically integrate these three types of models. We focus on the economic component of the assessment, investigating how nine global economic models of agriculture represent endogenous responses to seven standardized climate change scenarios produced by two climate and five crop models. These responses include adjustments in yields, area, consumption, and international trade. We apply biophysical shocks derived from the Intergovernmental Panel on Climate Change's representative concentration pathway with end-of-century radiative forcing of 8.5 W/m(sup 2). The mean biophysical yield effect with no incremental CO2 fertilization is a 17% reduction globally by 2050 relative to a scenario with unchanging climate. Endogenous economic responses reduce yield loss to 11%, increase area of major crops by 11%, and reduce consumption by 3%. Agricultural production, cropland area, trade, and prices show the greatest degree of variability in response to climate change, and consumption the lowest. The sources of these differences include model structure and specification; in particular, model assumptions about ease of land use conversion, intensification, and trade. This study identifies where models disagree on the relative responses to climate shocks and highlights research activities needed to improve the representation of agricultural adaptation responses to climate change.

Young Researcher Meeting, L'Aquila 2015

International Nuclear Information System (INIS)

Agostini, F; Antolini, C; Bossa, M; Cattani, G; Dell'Oro, S; D'Angelo, M; Di Stefano, M; Fragione, G; Migliaccio, M; Pagnanini, L; Pietrobon, D; Pusceddu, E; Serra, M; Stellato, F

2016-01-01

The Young Researcher Meeting (www.yrmr.it) has been established as a forum for students, postdoctoral fellows and young researchers determined to play a proactive role in the scientific progress. Since 2009, we run itinerant, yearly meetings to discuss the most recent developments and achievements in physics, as we are firmly convinced that sharing expertise and experience is the foundation of the research activity. One of the main purposes of the conference is actually to create an international network of young researchers, both experimentalists and theorists, and fruitful collaborations across the different branches of physics. The format we chose is an informal meeting primarily aimed at students and postdoctoral researchers at the beginning of their scientific career, who are encouraged to present their work in brief presentations able to provide genuine engagement of the audience and cross-pollination of ideas. The sixth edition of the Young Researcher Meeting was held at the Gran Sasso Science Institute (GSSI), L'Aquila. The high number of valuable contributions gave rise to a busy program for a two-day conference on October 12 th -13 th . The event gathered 70 participants from institutes all around the world. The plenary talk sessions covered several areas of pure and applied physics, and they were complemented by an extremely rich and interactive poster session. This year's edition of the meeting also featured a lectio magistralis by Prof. E. Coccia, director of the GSSI, who discussed the frontiers in gravitational wave physics, commemorating the International Year of Light on the centenary of Einstein's theory of general relativity. On October 14 th , the participants to the conference took part to a guided tour of the Gran Sasso National Laboratories (LNGS), one of the major particle physics laboratories in the world. In this volume, we collect part of the contributions that have been presented at the conference as either talks or

Polish Academy of Sciences Institute of Biochemistry and Biophysics research report 1994-1995

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-12-31

Scientific interests of Institute of Biochemistry and Biophysics Polish Academy of Sciences are focused on DNA replication and repair, gene expression, gene sequencing and molecular biophysics. The work reviews research projects of the Institute in 1994-1995.

Polish Academy of Sciences Institute of Biochemistry and Biophysics research report 1994-1995

International Nuclear Information System (INIS)

1996-01-01

Scientific interests of Institute of Biochemistry and Biophysics Polish Academy of Sciences are focused on DNA replication and repair, gene expression, gene sequencing and molecular biophysics. The work reviews research projects of the Institute in 1994-1995

Polish Academy of Sciences Institute of Biochemistry and Biophysics research report 1994-1995

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-12-31

Scientific interests of Institute of Biochemistry and Biophysics Polish Academy of Sciences are focused on DNA replication and repair, gene expression, gene sequencing and molecular biophysics. The work reviews research projects of the Institute in 1994-1995.

Surface-enhanced Raman scattering: a new optical probe in molecular biophysics and biomedicine

DEFF Research Database (Denmark)

Kneipp, J.; Wittig, B.; Bohr, Henrik

2010-01-01

Sensitive and detailed molecular structural information plays an increasing role in molecular biophysics and molecular medicine. Therefore, vibrational spectroscopic techniques, such as Raman scattering, which provide high structural information content are of growing interest in biophysical and ...

First meeting of the International Working Group on Advanced Technologies for Water Cooled Reactors, Vienna, 18-21 May 1987. (Pt. 1)

International Nuclear Information System (INIS)

1987-12-01

The first meeting of the IAEA International Working Group on Advanced Technologies for Water Cooled Reactors was held in Vienna, Austria from 18-21 May 1987. Part I of the Summary Report contains the minutes of the meeting

Abstracts of the 10. Annual meeting of the Federation of the Experimental Biological Societies; Resumos da 10. Reuniao anual da Federacao de Sociedades de Biologia Experimental

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-12-31

The meeting was about experimental biology and it was discussed topics related to medicine, pharmacology, cellular biology, biophysics, toxicology, physiology, immunology, radiobiology, photobiology, natural products and environment.

[Biophysical methods in assessment of the skin microcirculation system].

Science.gov (United States)

Dynnik, O B; Mostovoĭ, S E; Berezovskiĭ, V A

2008-01-01

In this work has been analyzed the potential of biophysics methods in estimations of the microcirculatory system. Capillaroresistometry, Computer capillaroscopy and Laser Doppler Flowmetry can to detect of the endothelial dysfunction in the patients with chronic hepatic diseases. This instrumentals biophysics methods may be used in clinical investigations for screening early pathological conditions with dysfunction of the microcirculatory system. The methods Laser Doppler Flowmetry is important for investigations the patients with others diseases and for dynamical monitoring by quality of the treatment. The purpose of these methods an objective estimation of disorders in the microcirculatory system.

Technical committee meeting on Liquid Metal Fast Reactor (LMFR) developments. 33rd annual meeting of the International Working Group on Fast Reactors (IWG-FR). Working material

International Nuclear Information System (INIS)

2000-01-01

Over the past 33 years, the IAEA has actively encouraged and advocated international cooperation in fast reactor technology. The present publication contains information on the status of fast reactor development and on worldwide activities in this advanced nuclear power technology during 1999/2000, as reported at the 33. annual meeting of the International Working Group on Fast Reactors. It is intended to provide information regarding the current status of LMFR development in IAEA Member States

Workshops of the Sixth International Brain–Computer Interface Meeting : brain–computer interfaces past, present, and future

NARCIS (Netherlands)

Huggins, Jane E.; Guger, Christoph; Ziat, Mounia; Zander, Thorsten O.; Taylor, Denise; Tangermann, Michael; Soria-Frisch, Aureli; Simeral, John; Scherer, Reinhold; Rupp, Rüdiger; Ruffini, Giulio; Robinson, Douglas K.R.; Ramsey, Nick F.; Nijholt, Anton; Müller-Putz, Gernot R.; McFarland, Dennis J.; Mattia, Donatella; Lance, Brent J.; Kindermans, Pieter-Jan; Iturrate, Iñaki; Herff, Christian; Gupta, Disha; Do, An H.; Collinger, Jennifer L.; Chavarriaga, Ricardo; Chasey, Steven M.; Bleichner, Martin G.; Batista, Aaron; Anderson, Charles W.; Aarnoutse, Erik J.

2017-01-01

The Sixth International Brain–Computer Interface (BCI) Meeting was held 30 May–3 June 2016 at the Asilomar Conference Grounds, Pacific Grove, California, USA. The conference included 28 workshops covering topics in BCI and brain–machine interface research. Topics included BCI for specific

International Experts' Meeting on Decommissioning and Remediation after a Nuclear Accident. Presentations

International Nuclear Information System (INIS)

2013-01-01

Against the backdrop of the accident at TEPCO's Fukushima Daiichi nuclear power plant in March 2011, the Director General of the International Atomic Energy Agency (IAEA) convened the IAEA Ministerial Conference on Nuclear Safety in Vienna, Austria, in June 2011. The Conference adopted a Ministerial Declaration which, inter alia, requested the Director General to prepare a draft Action Plan covering all the relevant aspects relating to nuclear safety, emergency preparedness and response, and radiation protection of people and the environment, as well as the relevant international legal framework. On 22 September 2011, the IAEA General Conference unanimously endorsed the draft IAEA Action Plan on Nuclear Safety approved by the Board of Governors. The Action Plan sets out a comprehensive programme of work, in 12 major areas, to strengthen nuclear safety worldwide. Under one of these areas, headed 'Enhance transparency and effectiveness of communication and improve dissemination of information', the IAEA Secretariat was requested to organize an International Experts' Meeting (IEM) on decommissioning, cleanup and remediation of nuclear facilities and contaminated lands after a nuclear accident. This IEM was organized in response to that request. The IEM focussed on the complex technical, societal, environmental and economic issues that need to be considered for decommissioning and remediation activities after a nuclear accident, specifically after the emergency exposure situation of an accident has been declared ended. The objective of the IEM is to assist Member States to prepare for and to be able to manage the consequences resulting from a nuclear accident. The meeting highlighted the specific short term and long term issues that may need to be addressed during decommissioning of facilities and remediation of the off-site environment affected by a nuclear accident. It is of interest to a wide range of experts, such as decision makers, regulators, operators

Engineered biomaterial and biophysical stimulation as combinatorial strategies to address prosthetic infection by pathogenic bacteria.

Science.gov (United States)

Boda, Sunil Kumar; Basu, Bikramjit

2017-10-01

A plethora of antimicrobial strategies are being developed to address prosthetic infection. The currently available methods for implant infection treatment include the use of antibiotics and revision surgery. Among the bacterial strains, Staphylococcus species pose significant challenges particularly, with regard to hospital acquired infections. In order to combat such life threatening infectious diseases, researchers have developed implantable biomaterials incorporating nanoparticles, antimicrobial reinforcements, surface coatings, slippery/non-adhesive and contact killing surfaces. This review discusses a few of the biomaterial and biophysical antimicrobial strategies, which are in the developmental stage and actively being pursued by several research groups. The clinical efficacy of biophysical stimulation methods such as ultrasound, electric and magnetic field treatments against prosthetic infection depends critically on the stimulation protocol and parameters of the treatment modality. A common thread among the three biophysical stimulation methods is the mechanism of bactericidal action, which is centered on biophysical rupture of bacterial membranes, the generation of reactive oxygen species (ROS) and bacterial membrane depolarization evoked by the interference of essential ion-transport. Although the extent of antimicrobial effect, normally achieved through biophysical stimulation protocol is insufficient to warrant therapeutic application, a combination of antibiotic/ROS inducing agents and biophysical stimulation methods can elicit a clinically relevant reduction in viable bacterial numbers. In this review, we present a detailed account of both the biomaterial and biophysical approaches for achieving maximum bacterial inactivation. Summarizing, the biophysical stimulation methods in a combinatorial manner with material based strategies can be a more potent solution to control bacterial infections. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B

Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease

OpenAIRE

Hosseini, Poorya; Abidi, Sabia Z.; Du, E; Papageorgiou, Dimitrios P.; Choi, Youngwoon; Park, YongKeun; Higgins, John M.; Kato, Gregory J.; Suresh, Subra; Dao, Ming; Yaqoob, Zahid; So, Peter T. C.

2016-01-01

There exists a critical need for developing biomarkers reflecting clinical outcomes and for evaluating the effectiveness of treatments for sickle cell disease patients. Prior attempts to find such patient-specific markers have mostly relied upon chemical biomarkers or biophysical properties at hypoxia with limited success. We introduce unique biomarkers based on characterization of cellular biophysical properties at normoxia and show that these markers correlate sensitively with treatment usi...

Biophysical behavior of Scomberoides commersonianus skin collagen.

Science.gov (United States)

Kolli, Nagamalleswari; Joseph, K Thomas; Ramasami, T

2002-06-01

Some biophysical characteristics of the skin collagen from Scomberoides commersonianus were measured and compared to those of rat tail tendon. Stress-strain data indicate that the strain at break as well as the tensile strength of the fish skin without scales increased significantly. The maximum tension in case of rat skin is at least a factor of two higher than that observed in fish skin. The much lower hydrothermal isometric tension measurements observed in fish skin are attributable to a lesser number of heat stable crosslinks. Stress relaxation measurements in the fish skin indicate that more than one relaxation process may be involved in the stabilization of collagenous matrix. The observed differences in the biophysical behavior of fish skin may well arise from combination of changes in extent of hydroxylation of proline in collagen synthesis, hydrogen bond network and fibril orientation as compared to rat tail tendon.

Summary report of the final technical meeting on 'International Reactor Dosimetry File: IRDF-2002'

International Nuclear Information System (INIS)

Griffin, Patrick J.; Paviotti-Corcuera, R.

2003-10-01

Presentations, recommendations and conclusions of the Final Technical Meeting on 'International Reactor Dosimetry File: IRDF-2002' are summarized in this report. The main aims of this meeting were to discuss scientific and technical matters related to reactor dosimetry and to assign responsibilities for the preparation of the final version of the IRDF- 2002 library and the associated TECDOC. Tasks were assigned and deadlines were agreed. Participants emphasized that accurate and complete nuclear data for reactor dosimetry are essential to improve the assessment accuracies for reactor pressure vessel service lifetimes in nuclear power plants, as well as for other neutron metrology applications such as boron neutron capture therapy, therapeutic use of medical isotopes, nuclear physics measurements, and reactor safety applications. (author)

Cell biology, biophysics, and mechanobiology: From the basics to Clinics.

Science.gov (United States)

Zeng, Y

2017-04-29

Cell biology, biomechanics and biophysics are the key subjects that guide our understanding in diverse areas of tissue growth, development, remodeling and homeostasis. Novel discoveries such as molecular mechanism, and mechanobiological mechanism in cell biology, biomechanics and biophysics play essential roles in our understanding of the pathogenesis of various human diseases, as well as in designing the treatment of these diseases. In addition, studies in these areas will also facilitate early diagnostics of human diseases, such as cardiovascular diseases and cancer. In this special issue, we collected 10 original research articles and 1 review...

Tumor radiosensitizers - current status of development of various approaches: Report of an International Atomic Energy Agency meeting

DEFF Research Database (Denmark)

Horsman, Michael Robert; Bohm, Lothar; Margison, Geoffrey P.

2006-01-01

PURPOSE: The International Atomic Energy Agency (IAEA) held a Technical Meeting of Consultants to (1) discuss a selection of relatively new agents, not those well-established in clinical practice, that operated through a variety of mechanisms to sensitize tumors to radiation and (2) to compare...... and contrast their tumor efficacy, normal tissue toxicity, and status of development regarding clinical application. The aim was to advise the IAEA as to which developing agent or class of agents would be worth promoting further, by supporting additional laboratory research or clinical trials...... and for clinical trials that would be suitable for industrialized countries, as well as trials that were considered more appropriate for developing countries.PURPOSE: The International Atomic Energy Agency (IAEA) held a Technical Meeting of Consultants to (1) discuss a selection of relatively new agents, not those...

Summary Report of the 1. Research Coordination Meeting on Testing and Improving the International Reactor Dosimetry and Fusion File (IRDFF)

International Nuclear Information System (INIS)

Trkov, A.; Greenwood, L.R.; Simakov, S.P.

2013-09-01

In accordance with the recommendations of the International Nuclear Data Committee in May 2012, the Nuclear Data Section of IAEA has initiated a new Coordinated Research Project (CRP number F41031) with the main goal to test, validate and improve the international dosimetry library for fission and fusion (IRDFF). The output of this CRP will be a reference dosimetry database of cross sections and decay data with corresponding documentation. It will serve to the needs of fission, fusion and accelerator applications. The first Research Coordination Meeting (RCM) was held 1 to 5 July 2013 in IAEA. At this meeting, the attendees discussed the objectives of the whole CRP, presented their contributions and elaborated on consolidated recommendations and actions for implementation over the next 1.5 year period. This Summary Report documents the individual contributions and joint decisions made during this meeting. (author)

Ninth meeting of the International Working Group on Gas Cooled Reactors, Oak Ridge, USA, 8-9 November 1990

International Nuclear Information System (INIS)

1991-05-01

This report contains the minutes of the meeting, the papers presented as overview of the national programmes in the field of gas-cooled reactors and the main results from discussions on the different items of the agenda. The meeting was attended by 20 members and/or alternates from 9 countries and 2 international organizations. 8 papers were presented. A separate abstract was prepared for each of these papers. Refs, figs and tabs

Sonographic biophysical profile in detection of foetal hypoxia in 100 cases of suspected high risk pregnancy

International Nuclear Information System (INIS)

Ullah, N.; Khan, A.R.; Usman, M.

2010-01-01

Background: The foetus has become increasingly accessible and visible as a patient over the last two decades. Ultrasound imaging has broadened the scope of foetal assessment. Dynamic real time B-Mode ultrasound is used to monitor cluster of biophysical variables, both dynamic and static collectively termed as biophysical profile. The purpose of this study was to determine the effect of sonographic biophysical profile score on perinatal outcome in terms of mortality and morbidity. Methods: This descriptive study was carried on 100 randomly select ed high risk pregnant patients in Radiology Department PGMI, Government Lady Reading Hospital, Peshawar from December 2007 to June 2008. Manning biophysical profile including non-stress was employed for foetal screening, using Toshiba ultrasound machine model Nemio SSA-550A and 7.5 MHZ probe. Results: Out of 100 cases 79 (79%) had a normal biophysical profile in the last scan of 10/10 and had a normal perinatal outcome with 5 minutes Apgar score >7/10. In 13 (13%) cases Apgar score at 5 minute was < 7/10 and babies were shifted to nursery. There were 2 (2%) false positive cases that showed abnormal biophysical profile scores of 6/10 but babies were born with an Apgar score of 8/10 at 5 minutes. There were 2 (2%) neonatal deaths in this study group. The sensitivity of biophysical profile was 79.1%, specificity 92.9%. Predictive value for a positive test was 98.55%; predictive value for a negative test was 41.93%. Conclusion: Biophysical profile is highly accurate and reliable test of diagnosing foetal hypoxia. (author)

Effect of ambient light on the time needed to complete a fetal biophysical profile: A randomized controlled trial.

Science.gov (United States)

Said, Heather M; Gupta, Shweta; Vricella, Laura K; Wand, Katy; Nguyen, Thinh; Gross, Gilad

2017-10-01

The objective of this study is to determine whether ambient light serves as a fetal stimulus to decrease the amount of time needed to complete a biophysical profile. This is a randomized controlled trial of singleton gestations undergoing a biophysical profile. Patients were randomized to either ambient light or a darkened room. The primary outcome was the time needed to complete the biophysical profile. Secondary outcomes included total and individual component biophysical profile scores and scores less than 8. A subgroup analysis of different maternal body mass indices was also performed. 357 biophysical profile studies were analyzed. 182 studies were performed with ambient light and 175 were performed in a darkened room. There was no difference in the median time needed to complete the biophysical profile based on exposure to ambient light (6.1min in darkened room versus 6.6min with ambient light; P=0.73). No difference was found in total or individual component biophysical profile scores. Subgroup analysis by maternal body mass index did not demonstrate shorter study times with ambient light exposure in women who were normal weight, overweight or obese. Ambient light exposure did not decrease the time needed to complete the biophysical profile. There was no evidence that ambient light altered fetal behavior observed during the biophysical profile. Copyright © 2017 Elsevier B.V. All rights reserved.

Synthetic Biology: Engineering Living Systems from Biophysical Principles.

Science.gov (United States)

Bartley, Bryan A; Kim, Kyung; Medley, J Kyle; Sauro, Herbert M

2017-03-28

Synthetic biology was founded as a biophysical discipline that sought explanations for the origins of life from chemical and physical first principles. Modern synthetic biology has been reinvented as an engineering discipline to design new organisms as well as to better understand fundamental biological mechanisms. However, success is still largely limited to the laboratory and transformative applications of synthetic biology are still in their infancy. Here, we review six principles of living systems and how they compare and contrast with engineered systems. We cite specific examples from the synthetic biology literature that illustrate these principles and speculate on their implications for further study. To fully realize the promise of synthetic biology, we must be aware of life's unique properties. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

78 FR 16665 - International Energy Agency Meetings

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2013-03-18

... this notice is to permit attendance by representatives of U.S. company members of the IAB at a meeting... meeting among company representatives at the same location at 8:30 a.m. on March 26. The agenda for this... Refining Crisis 8. Middle East Energy Exports and the Arab Spring 9. The Turmoil in North Africa and the...

77 FR 69613 - International Energy Agency Meeting

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2012-11-20

... Policy and Conservation Act (42 U.S.C. 6272(c)(1)(A)(i)) (EPCA), the following notice of meeting is... the IEA 2. IEA Emergency Response Policies, Market Assessment, Industry Perspective 3. IEA Oil Data...)(A)(ii) of the Energy Policy and Conservation Act (42 U.S.C. 6272(c)(1)(A)(ii)), the meeting of the...

UN legal advisers meet

International Nuclear Information System (INIS)

1969-01-01

Legal Advisers from twelve international organizations belonging to the United Nations Organization's family met at the Agency's Headquarters in Vienna on 19 and 20 May to discuss legal problems of common administrative interest. The meeting was held on the initiative of the Agency while the UN Conference on the Law of Treaties was taking place in Vienna during April and May. With Mr. Constantin A. Stavropoulos, Under-Secretary, Legal Counsel of the United Nations, as chairman, this was the second meeting of Legal Advisers since 1954. The following organizations were represented: Food and Agriculture Organization of the United Nations, International Atomic Energy Agency, International Bank for Reconstruction and Development, International Civil Aviation Organization, International Labour Organisation, Inter-Governmental Maritime Consultative Organization, International Monetary Fund, International Telecommunication Union, United Nations, United Nations Educational, Scientific and Cultural Organization, United Nations Industrial Development Organization, World Health Organization. Topics discussed included the recruitment of legal staff and possible exchange of staff between organizations; competence and procedure of internal appeals committees, experience with cases before the Administrative Tribunals and evaluation of their judgments; experience with Staff Credit Unions; privileges and immunities of international organizations; headquarters and host government agreements; and patent policies of international organizations. Consultations will continue through correspondence and further meetings. (author)

Co-ordination of the International Network of Nuclear Structure and Decay Data Evaluators. Summary report of an IAEA Technical Meeting

International Nuclear Information System (INIS)

Nichols, A.L.; Tuli, J.K.

2007-09-01

The IAEA Nuclear Data Section convened the 17th meeting of the International Network of Nuclear Structure and Decay Data Evaluators in St. Petersburg, Russian Federation, 11-15 June 2007. This meeting was attended by 27 scientists from 13 Member States concerned with the compilation, evaluation and dissemination of nuclear structure and decay data. A summary of the meeting, recommendations/conclusions, data centre reports, and various proposals considered, modified and agreed by the participants are contained within this document. (author)

Proceedings of the fifteenth meeting of the international collaboration on advanced neutron sources (ICANS-XV). Advanced neutron sources towards the next century

Energy Technology Data Exchange (ETDEWEB)

Suzuki, Jun-ichi [Center for Neutron Science, Tokai Research Establishment, Japan Atomic Energy Research Institute, Tokai, Ibaraki (Japan); Itoh, Shinichi [Neutron Science Laboratory, High Energy Accelerator Research Organization, Tsukuba, Ibaraki (JP)

2001-03-01

The fifteenth meeting of the International Collaboration on Advanced Neutron Sources (ICANS-XV) was held at Epocal Tsukuba, International Congress Center on 6-9 November 2000. It was hosted by Japan Atomic Energy Research Institute (JAERI) and High Energy Accelerator Research Organization (KEK). This meeting focused on 'Neutron Sources toward the 21st Century' and research activities related to targets and moderators, neutron scattering instruments and accelerators were presented. The 151 of the presented papers are indexed individually. (J.P.N.)

Proceedings of the fifteenth meeting of the international collaboration on advanced neutron sources (ICANS-XV). Advanced neutron sources towards the next century

Energy Technology Data Exchange (ETDEWEB)

Suzuki, Jun-ichi [Center for Neutron Science, Tokai Research Establishment, Japan Atomic Energy Research Institute, Tokai, Ibaraki (Japan); Itoh, Shinichi [Neutron Science Laboratory, High Energy Accelerator Research Organization, Tsukuba, Ibaraki (JP)] (eds.)

2001-03-01

The fifteenth meeting of the International Collaboration on Advanced Neutron Sources (ICANS-XV) was held at Epocal Tsukuba, International Congress Center on 6-9 November 2000. It was hosted by Japan Atomic Energy Research Institute (JAERI) and High Energy Accelerator Research Organization (KEK). This meeting focused on 'Neutron Sources toward the 21st Century' and research activities related to targets and moderators, neutron scattering instruments and accelerators were presented. The 151 of the presented papers are indexed individually. (J.P.N.)

Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease.

Science.gov (United States)

Hosseini, Poorya; Abidi, Sabia Z; Du, E; Papageorgiou, Dimitrios P; Choi, Youngwoon; Park, YongKeun; Higgins, John M; Kato, Gregory J; Suresh, Subra; Dao, Ming; Yaqoob, Zahid; So, Peter T C

2016-08-23

Hydroxyurea (HU) has been used clinically to reduce the frequency of painful crisis and the need for blood transfusion in sickle cell disease (SCD) patients. However, the mechanisms underlying such beneficial effects of HU treatment are still not fully understood. Studies have indicated a weak correlation between clinical outcome and molecular markers, and the scientific quest to develop companion biophysical markers have mostly targeted studies of blood properties under hypoxia. Using a common-path interferometric technique, we measure biomechanical and morphological properties of individual red blood cells in SCD patients as a function of cell density, and investigate the correlation of these biophysical properties with drug intake as well as other clinically measured parameters. Our results show that patient-specific HU effects on the cellular biophysical properties are detectable at normoxia, and that these properties are strongly correlated with the clinically measured mean cellular volume rather than fetal hemoglobin level.

PREFACE: ELC International Meeting on Inference, Computation, and Spin Glasses (ICSG2013)

Science.gov (United States)

Kabashima, Yoshiyuki; Hukushima, Koji; Inoue, Jun-ichi; Tanaka, Toshiyuki; Watanabe, Osamu

2013-12-01

The close relationship between probability-based inference and statistical mechanics of disordered systems has been noted for some time. This relationship has provided researchers with a theoretical foundation in various fields of information processing for analytical performance evaluation and construction of efficient algorithms based on message-passing or Monte Carlo sampling schemes. The ELC International Meeting on 'Inference, Computation, and Spin Glasses (ICSG2013)', was held in Sapporo 28-30 July 2013. The meeting was organized as a satellite meeting of STATPHYS25 in order to offer a forum where concerned researchers can assemble and exchange information on the latest results and newly established methodologies, and discuss future directions of the interdisciplinary studies between statistical mechanics and information sciences. Financial support from Grant-in-Aid for Scientific Research on Innovative Areas, MEXT, Japan 'Exploring the Limits of Computation (ELC)' is gratefully acknowledged. We are pleased to publish 23 papers contributed by invited speakers of ICSG2013 in this volume of Journal of Physics: Conference Series. We hope that this volume will promote further development of this highly vigorous interdisciplinary field between statistical mechanics and information/computer science. Editors and ICSG2013 Organizing Committee: Koji Hukushima Jun-ichi Inoue (Local Chair of ICSG2013) Yoshiyuki Kabashima (Editor-in-Chief) Toshiyuki Tanaka Osamu Watanabe (General Chair of ICSG2013)

Summary report of the technical meeting on 'International Reactor Dosimetry File: IRDF-2002'

International Nuclear Information System (INIS)

Greenwood, L.R.; Paviotti-Corcuera, R.

2002-09-01

This report summarizes the presentations, recommendations and conclusions of the Technical Meeting on 'International Reactor Dosimetry File: IRDF-2002.' The purpose of this meeting was to discuss scientific and technical matters related to the subject and coordinate related tasks. Discussions were held and recommendations were given for the preparation of the files on topics related to: reactions to be included, need for new evaluations or revisions, decay data, radiation damage data, integral testing in benchmark fields, and computer codes to be included. Tasks were assigned and deadlines were set. The participants emphasized that accurate and complete knowledge of nuclear data for reactor dosimetry are essential for improving the accuracy of the reactor pressure vessel service life assessment of nuclear power plants as well as in other neutron metrology applications such as boron neutron capture therapy, therapeutic use of medical isotopes, nuclear physics measurements, and reactor safety applications. (author)

Biophysical radiosensitization

International Nuclear Information System (INIS)

Vladescu, C.; Apetroae, M.

1983-01-01

Experimental studies on normal and tumor-bearing rats revealed that chronic treatment with hydroquinone (5 mg/kg/day) inhibited catalase activity in liver, spleen, blood, and H 18R tumor. 3 H-hydroquinone (1.5 μCi/g body weight) showed tumor specificity, with maximum radioactivity in the tumor at 1 h after administration. The biological half-time of 3 H-hydroquinone in the tumor was 2 h, but there seems to exist a longer component, since 24 h after administration, some 30% of the maximum radioactivity could be detected in the tumor. Hydroquinone treatment produces a specific inhibition of catalase in the tumor and a higher degree of oxygenation at this level. These findings support the assumption that the mechanism of action of hydroquinone as an anticancer agent is achieved mainly via peroxide production. The oxygenation of the hypoxic tumoral tissue is done at non-toxic levels of hydroquinone, through a natural and specific biophysical pathway, recommanding hydroquinone for combined anticancer treatment (radiotherapy and chemotherapy). (orig.)

First meeting of the International Working Group on Advanced Technologies for Water Cooled Reactors, Vienna, 18-21 May 1987. (Pt. 2)

International Nuclear Information System (INIS)

1987-12-01

The First Meeting of the IAEA International Working Group on Advanced Technologies for Water Cooled Reactors was held in Vienna, Austria from 18-21 May 1987. The Summary Report (Pt. 2) contains the papers which review the national programmes in the field of Advanced Technologies for Water Cooled Reactors and other presentations at the Meeting. A separate abstract was prepared for each of the 10 papers presented at this meeting. Refs, figs

The biophysics of renal sympathetic denervation using radiofrequency energy.

Science.gov (United States)

Patel, Hitesh C; Dhillon, Paramdeep S; Mahfoud, Felix; Lindsay, Alistair C; Hayward, Carl; Ernst, Sabine; Lyon, Alexander R; Rosen, Stuart D; di Mario, Carlo

2014-05-01

Renal sympathetic denervation is currently performed in the treatment of resistant hypertension by interventionists who otherwise do not typically use radiofrequency (RF) energy ablation in their clinical practice. Adequate RF lesion formation is dependent upon good electrode-tissue contact, power delivery, electrode-tissue interface temperature, target-tissue impedance and the size of the catheter's active electrode. There is significant interplay between these variables and hence an appreciation of the biophysical determinants of RF lesion formation is required to provide effective and safe clinical care to our patients. In this review article, we summarize the biophysics of RF ablation and explain why and how complications of renal sympathetic denervation may occur and discuss methods to minimise them.

Raman spectroscopy reveals biophysical markers in skin cancer surgical margins

Science.gov (United States)

Feng, Xu; Moy, Austin J.; Nguyen, Hieu T. M.; Zhang, Yao; Fox, Matthew C.; Sebastian, Katherine R.; Reichenberg, Jason S.; Markey, Mia K.; Tunnell, James W.

2018-02-01

The recurrence rate of nonmelanoma skin cancer is highly related to the residual tumor after surgery. Although tissueconserving surgery, such as Mohs surgery, is a standard method for the treatment of nonmelanoma skin cancer, they are limited by lengthy and costly frozen-section histopathology. Raman spectroscopy (RS) is proving to be an objective, sensitive, and non-destructive tool for detecting skin cancer. Previous studies demonstrated the high sensitivity of RS in detecting tumor margins of basal cell carcinoma (BCC). However, those studies rely on statistical classification models and do not elucidate the skin biophysical composition. As a result, we aim to discover the biophysical differences between BCC and primary normal skin structures (including epidermis, dermis, hair follicle, sebaceous gland and fat). We obtained freshly resected ex vivo skin samples from fresh resection specimens from 14 patients undergoing Mohs surgery. Raman images were acquired from regions containing one or more structures using a custom built 830nm confocal Raman microscope. The spectra were grouped using K-means clustering analysis and annotated as either BCC or each of the five normal structures by comparing with the histopathology image of the serial section. The spectral data were then fit by a previously established biophysical model with eight primary skin constituents. Our results show that BCC has significant differences in the fit coefficients of nucleus, collagen, triolein, keratin and elastin compared with normal structures. Our study reveals RS has the potential to detect biophysical changes in resection margins, and supports the development of diagnostic algorithms for future intraoperative implementation of RS during Mohs surgery.

78 FR 69172 - U.S. Department of State Advisory Committee on Private International Law (ACPIL): Public Meeting...

Science.gov (United States)

2013-11-18

... International Law (ACPIL): Public Meeting on Electronic Commerce The Office of the Assistant Legal Adviser for... IV (electronic commerce), the UNCITRAL Secretariat has prepared draft provisions on electronic...://www.uncitral.org/uncitral/en/commission/working_groups/4Electronic_Commerce.html . This Working Paper...

77 FR 71828 - Meeting of the Advisory Committee; Meeting

Science.gov (United States)

2012-12-04

... recommended for inclusion on future Joint Board examinations in actuarial mathematics and methodology referred... meeting of the Advisory Committee on Actuarial Examinations (portions of which will be open to the public... Committee on Actuarial Examinations will meet at the Internal Revenue Service, 1111 Constitution Avenue NW...

75 FR 76486 - Meeting of the Advisory Committee; Meeting

Science.gov (United States)

2010-12-08

... that may be recommended for inclusion on future Joint Board examinations in actuarial mathematics and... meeting of the Advisory Committee on Actuarial Examinations (portions of which will be open to the public... the Advisory Committee on Actuarial Examinations will meet at the Internal Revenue Service, 1111...

X-Ray structure and biophysical properties of rabbit fibroblast growth factor 1

Energy Technology Data Exchange (ETDEWEB)

Lee, Jihun; Blaber, Sachiko I.; Irsigler, Andre; Aspinwall, Eric; Blaber, Michael; (FSU)

2010-01-14

The rabbit is an important and de facto animal model in the study of ischemic disease and angiogenic therapy. Additionally, fibroblast growth factor 1 (FGF-1) is emerging as one of the most important growth factors for novel pro-angiogenic and pro-arteriogenic therapy. However, despite its significance, the fundamental biophysical properties of rabbit FGF-1, including its X-ray structure, have never been reported. Here, the cloning, crystallization, X-ray structure and determination of the biophysical properties of rabbit FGF-1 are described. The X-ray structure shows that the amino-acid differences between human and rabbit FGF-1 are solvent-exposed and therefore potentially immunogenic, while the biophysical studies identify differences in thermostability and receptor-binding affinity that distinguish rabbit FGF-1 from human FGF-1.

Global issues from an African point of view. 7th International Women and Health Meeting in Uganda.

Science.gov (United States)

Shallat, L

1993-01-01

The seventh International Women and Health Meeting (IWHM) was held in Kampala, Uganda, during September 12-17, 1993. The purpose of the meeting was to devise strategies to confront such issues as the impact of economic policies on women's health, the implementation of reproductive rights, population control and policies, contraceptive technologies, AIDS, and sexual abuse and violence. In addition to these topics, discussion centered on interaction with the upcoming 1994 International Conference on Population and Development. Some participants were frustrated, however, by the procedural problems that prevented creation of a cohesive position paper and left important strategic questions unanswered. Women from Latin America and the Caribbean were kept from full participation by the lack of a Spanish translator but nevertheless held an information session on regional developments in abortion reform and population policy. These women were also successful in their bid to host the eighth IWHM in Brazil in 1996.

Co-ordination of the International Network of Nuclear Structure and Decay Data Evaluators. Summary report of an IAEA technical meeting

International Nuclear Information System (INIS)

Abriola, D.; Tuli, J.K.

2009-10-01

The IAEA Nuclear Data Section convened the 18th meeting of the International Network of Nuclear Structure and Decay Data Evaluators at the IAEA Headquarters, Vienna, 23 to 27 March 2009. This meeting was attended by 22 scientists from 14 Member States, plus IAEA staff, concerned with the compilation, evaluation and dissemination of nuclear structure and decay data. A summary of the meeting, recommendations/conclusions, data centre reports, and various proposals considered, modified and agreed by the participants are contained within this document. (author)

Co-ordination of the International Network of Nuclear Structure and Decay Data Evaluators. Summary report of an IAEA technical meeting

Energy Technology Data Exchange (ETDEWEB)

Nichols, A L; Tuli, J K [International Atomic Energy Agency, Nuclear Data Section, Vienna (Austria)

2005-09-15

The IAEA Nuclear Data Section convened the 16th meeting of the International Network of Nuclear Structure and Decay Data Evaluators at the Department of Physics and Astronomy, McMaster University, Hamilton, Canada, 6-10 June 2005. This meeting was attended by 33 scientists from 12 Member States concerned with the compilation, evaluation and dissemination of nuclear structure and decay data. A summary of the meeting, recommendations/conclusions, data centre reports, and various proposals considered, modified and agreed by the participants are contained within this document. (author)

8th International Congress on Biocatalysis (Biocat2016), Hamburg, Germany, 28 August - 1 September, 2016 : meeting report

OpenAIRE

Elleuche, Skander; Esselun, Petra; Grote, Ralf; Klippel, Barbara; Krüger, Anna; Liese, Andreas; Ostrop, Margit; Schäfers, Christian; Schröder, Carola; Antranikian, Garabed

2016-01-01

The “8th International Congress on Biocatalysis (biocat2016)” is part of a biennial conference series. Biocatalysis is a topic based on the edge of biology and chemistry, which brings together scientists from the life sciences, engineers and computer scientists. This international conference serves as a platform to meet researchers from all over the world, to find collaboration partners for future projects and to gain novel insights into modern topics and techniques. Biocat covers the most...

Trends in Attendance at Scoliosis Research Society Annual Meetings (SRS AM) and International Meeting on Advanced Spine Techniques (IMAST): Location, Location, Location.

Science.gov (United States)

Chen, Foster; Cho, Woojin; Kim, Han Jo; Levine, David B

2017-07-01

Descriptive, respective. Although overall membership in Scoliosis Research Society (SRS) has grown over the years, we were curious to see the effects of changing event venue location and timing on conference attendance. Every year, the SRS hosts two major meetings: the Annual Meeting (SRS AM) in the autumn, and the International Meeting on Advanced Spine Techniques (IMAST) in the summer. Sites have alternated from within and outside North America. Often, these meetings have also overlapped with several holidays in certain countries. This was an observational study of attendance from past SRS AM and IMAST meetings. Fourteen years of AM and 8 years of IMAST data were made available from the SRS. Participation based on delegate type and countries were tallied. Details from the 10 most represented nations and host nations per year were also tallied, and their national holidays were reviewed for overlaps with the AM. Membership in AM and IMAST increased from 820 in 2003 to 1,323 in 2016. Attendance at the AM has increased, whereas attendance at IMAST has declined, even after adjusting for membership size. Trends in participation were highly influenced by location. Participation by attendees from the host continent, and especially the host country, is generally high. The negative impact of distant meetings is profoundly seen with North Americans, whereas the positive impact of a nearby meeting was mostly clearly demonstrated by South Americans. Although SRS AM overlapped with holidays in China, Japan, or Korea nearly 50% of the time, this did not influence participation by delegates from these countries. Participation in the AM is highly influenced by location. Although North Americans represented the largest constituency, their presence was not needed to drive total attendance and was not sufficient to turn around the downturn in IMAST attendance. Choice of location can encourage the participation of delegates from the host and neighboring nations; through strategic

PREFACE: 8th Asian International Seminar on Atomic and Molecular Physics (AISAMP)

Science.gov (United States)

Williams, Jim F.; Buckman, Steve; Bieske, Evan J.

2009-09-01

These proceedings arose from the 8th Asian International Seminar on Atomic and Molecular Physics (AISAMP) which was held at the University of Western Australia 24-28 November 2008. The history of AISAMP (Takayanagi and Matsuzawa 2002) recognizes its origin from the Japan-China meeting of 1985, and the first use of the name 'The First Asian International Seminar on Atomic and Molecular Physics (AISAMP)' in 1992. The initial attendees, Japan and China, were joined subsequently by scientists from Korea, Taiwan, India, Australia and recently by Malaysia, Thailand, Vietnam, Turkey Iran, UK and USA. The main purpose of the biennial AISAMP series is to create a wide forum for exchanging ideas and information among atomic and molecular scientists and to promote international collaboration. The scope of the AISAMP8 meeting included pure, strategic and applied research involving atomic and molecular structure and processes in all forms of matter and antimatter. For 2008 the AISAMP conference incorporated the Australian Atomic and Molecular Physics and Quantum Chemistry meeting. The topics for AISAMP8 embraced themes from earlier AISAMP meetings and reflected new interests, in atomic and molecular structures, spectroscopy and collisions; atomic and molecular physics with laser or synchrotron radiation; quantum information processing using atoms and molecules; atoms and molecules in surface physics, nanotechnology, biophysics, atmospheric physics and other interdisciplinary studies. The implementation of the AISAMP themes, as well as the international representation of research interests, is indicated both in the contents list of these published manuscripts as well as in the program for the meeting. Altogether, 184 presentations were made at the 8th AISAMP, including Invited Talks and Contributed Poster Presentations, of which 60 appear in the present Proceedings after review by expert referees in accordance with the usual practice of Journal of Physics: Conference Series of

Chief, Structural Biophysics Laboratory | Center for Cancer Research

Science.gov (United States)

The SBL Chief is expected to establish a strong research program in structural biology/biophysics in addition to providing leadership of the SBL and the structural biology community in the NCI Intramural Program.  Applicants should hold a Ph.D., M.D./Ph.D., or equivalent doctoral degree in a relevant discipline, and should possess outstanding communication skills and documented leadership experience.  Tenured faculty or industrial scientists of equivalent rank with a demonstrated commitment to structural biophysics should apply.  Salary will be commensurate with experience and accomplishments.  This position is not restricted to U.S. citizens. A full civil service package of benefits (including health insurance, life insurance, and retirement) is available. This position is subject to a background investigation.  The NIH is dedicated to building a diverse community in its training and employment programs.

Socialization at the morning meeting

DEFF Research Database (Denmark)

Rimestad, L.; Gravengaard, Gitte

2016-01-01

In this ethnographic study we examine how journalism interns present ideas at morning meetings in the professional environment of a media organization. We analyse not only the idea presentation at the meeting itself, but also how editors treat the idea presentation, and how the interns perceive...

75 FR 28062 - Meeting of the Advisory Committee; Meeting

Science.gov (United States)

2010-05-19

... questions which may be recommended for inclusion on future Joint Board examinations in actuarial mathematics... meeting of the Advisory Committee on Actuarial Examinations (a portion of which will be open to the public... the Advisory Committee on Actuarial Examinations will meet in at the Internal Revenue Service Building...

Quality Saving Mechanisms of Mitochondria during Aging in a Fully Time-Dependent Computational Biophysical Model.

Directory of Open Access Journals (Sweden)

Daniel Mellem

Full Text Available Mitochondria are essential for the energy production of eukaryotic cells. During aging mitochondria run through various processes which change their quality in terms of activity, health and metabolic supply. In recent years, many of these processes such as fission and fusion of mitochondria, mitophagy, mitochondrial biogenesis and energy consumption have been subject of research. Based on numerous experimental insights, it was possible to qualify mitochondrial behaviour in computational simulations. Here, we present a new biophysical model based on the approach of Figge et al. in 2012. We introduce exponential decay and growth laws for each mitochondrial process to derive its time-dependent probability during the aging of cells. All mitochondrial processes of the original model are mathematically and biophysically redefined and additional processes are implemented: Mitochondrial fission and fusion is separated into a metabolic outer-membrane part and a protein-related inner-membrane part, a quality-dependent threshold for mitophagy and mitochondrial biogenesis is introduced and processes for activity-dependent internal oxidative stress as well as mitochondrial repair mechanisms are newly included. Our findings reveal a decrease of mitochondrial quality and a fragmentation of the mitochondrial network during aging. Additionally, the model discloses a quality increasing mechanism due to the interplay of the mitophagy and biogenesis cycle and the fission and fusion cycle of mitochondria. It is revealed that decreased mitochondrial repair can be a quality saving process in aged cells. Furthermore, the model finds strategies to sustain the quality of the mitochondrial network in cells with high production rates of reactive oxygen species due to large energy demands. Hence, the model adds new insights to biophysical mechanisms of mitochondrial aging and provides novel understandings of the interdependency of mitochondrial processes.

Proceedings of the international topical meeting on remote systems and robotics in hostile environments

International Nuclear Information System (INIS)

Anon.

1987-01-01

This book contains the proceedings of the International Topical Meeting on Remote Systems and Robotics in Hostile Environments. It is organized under the following sessions: Worldwide Applications Overview; Operating Mobile Systems; Sensors and Control Systems; Space Applications; Reactor Operations and Surveillance; Remote Equipment for Hazardous Operations; Future Mobile System; Mining and Construction Operations; Special Applications; Hot Cell Applications; Processing; Reactor Operations and Maintenance; Decontamination and Waste Handling; Remote Handling Development and Demonstration

International Working Group on Water Reactor Fuel Performance and Technology. Summary report of the 14. plenary meeting. Working material

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-12-01

The fourteenth Plenary Meeting of the International Working Group on Water Reactor Fuel Performance and Technology (IWGFPT) was held at IAEA Headquarters, Vienna, from 21 to 23 May 1997. Twenty-seven participants, from twenty two Member States and two international organizations, attended the meeting. These presentations generally gave: The general situation of the nuclear industry in the country; Fuel fabrication; Fuel performance, high burnup fuel (including MOX) operational experience; Status and trends in fuel research programmes directed to achievement sufficient safety margins at high burnups with regard to normal and transient operational conditions. Majority of countries reported on the stable situation of the nuclear fuel industry, i.e. without significant additions/cuts in nuclear power plant and fuel fabrication plant (NPP) capacities. Refs, figs, tabs.

International Working Group on Water Reactor Fuel Performance and Technology. Summary report of the 14. plenary meeting. Working material

International Nuclear Information System (INIS)

1997-01-01

The fourteenth Plenary Meeting of the International Working Group on Water Reactor Fuel Performance and Technology (IWGFPT) was held at IAEA Headquarters, Vienna, from 21 to 23 May 1997. Twenty-seven participants, from twenty two Member States and two international organizations, attended the meeting. These presentations generally gave: The general situation of the nuclear industry in the country; Fuel fabrication; Fuel performance, high burnup fuel (including MOX) operational experience; Status and trends in fuel research programmes directed to achievement sufficient safety margins at high burnups with regard to normal and transient operational conditions. Majority of countries reported on the stable situation of the nuclear fuel industry, i.e. without significant additions/cuts in nuclear power plant and fuel fabrication plant (NPP) capacities. Refs, figs, tabs

Satellite mapping of surface biophysical parameters at the biome scale over the North American grasslands: A case study

Science.gov (United States)

Wylie, B.K.; Meyer, D.J.; Tieszen, L.L.; Mannel, S.

2002-01-01

Quantification of biophysical parameters is needed by terrestrial process modeling and other applications. A study testing the role of multispectral data for monitoring biophysical parameters was conducted over a network of grassland field sites in the Great Plains of North America. Grassland biophysical parameters [leaf area index (LAI), fraction of absorbed photosynthetically active radiation (fPAR), and biomass] and their relationships with ground radiometer normalized difference vegetation index (NDVI) were established in this study (r2=.66–.85) from data collected across the central and northern Great Plains in 1995. These spectral/biophysical relationships were compared to 1996 field data from the Tallgrass Prairie Preserve in northeastern Oklahoma and showed no consistent biases, with most regression estimates falling within the respective 95% confidence intervals. Biophysical parameters were estimated for 21 “ground pixels” (grids) at the Tallgrass Prairie Preserve in 1996, representing three grazing/burning treatments. Each grid was 30×30 m in size and was systematically sampled with ground radiometer readings. The radiometric measurements were then converted to biophysical parameters and spatially interpolated using geostatistical kriging. Grid-based biophysical parameters were monitored through the growing season and regressed against Landsat Thematic Mapper (TM) NDVI (r2=.92–.94). These regression equations were used to estimate biophysical parameters for grassland TM pixels over the Tallgrass Prairie Preserve in 1996. This method maintained consistent regression development and prediction scales and attempted to minimize scaling problems associated with mixed land cover pixels. A method for scaling Landsat biophysical parameters to coarser resolution satellite data sets (1 km2) was also investigated.

1st International Symposium ‘Physics, Engineering and Technologies for Bio-Medicine’

International Nuclear Information System (INIS)

2017-01-01

The 1st International Symposium “Physics, Engineering and Technologies for BioMedicine” was held in Moscow at the occasion of the foundation of the new Institute PhysBio at MEPHI (Russia) on October 20-23, 2016. Under the auspices of the Russian Ministry of Science and Education, the Ministry of Health and the State Company Rosatom, the Symposium is organized by the Institute of Engineering Physics for Biomedicine (PhysBio), which has recently been established at National Research Nuclear University MEPhI (Moscow Engineering Physics Institute). The PhysBio’s goal is to train highly-skilled personnel through the research and development in engineering physics for biomedicine, including nuclear medicine, material science, laser physics and biophotonic technologies. The Symposium was aimed to meet the leading scientists and experts in nuclear medicine, biophysics, biophotonics, and emerging fields to present their works and to have invited lectures. (paper)

International Materials Research Meeting in the Greater Region: “Current Trends in the Characterisation of Materials and Surface Modification”

Science.gov (United States)

2017-10-01

Preface Dear ladies and gentlemen, On 6th and 7th of April 2017 took place the “International Materials Research Meeting in the Greater Region” at the Saarland University, Saarbrücken, Germany. This meeting corresponded to the 9th EEIGM International Conference on Advanced Materials Research and it was intended as a meeting place for researchers of the Greater Region as well as their partners of the different cooperation activities, like the EEIGM program, the ‘Erasmus Mundus’ Advanced Materials Science and Engineering Master program (AMASE), the ‘Erasmus Mundus’ Doctoral Program in Materials Science and Engineering (DocMASE) and the CREATe-Network. On this meeting, 72 participants from 15 countries and 24 institutions discussed and exchanged ideas on the latest trends in the characterization of materials and surface modifications. Different aspects of the material research of metals, ceramics, polymers and biomaterials were presented. As a conclusion of the meeting, the new astronaut of the European Space Agency Dr. Matthias Maurer, who is an alumni of the Saarland University and the EEIGM, held an exciting presentation about his activities. Following the publication of selected papers of the 2009 meeting in Volume 5 and 2012 meeting in Volume 31 of this journal, it is a great pleasure to present this selection of 9 articles to the readers of the IOP Conference Series: Materials Science and Engineering. The editors are thankful to all of the reviewers for reviewing the papers. Special praise is also given to the sponsors of the conference: European Commission within the program Erasmus Mundus (AMASE and DocMASE), Erasmus+ (AMASE), and Horizon2020 (CREATe-Network, Grant agreement No 644013): the DAAD (Alumni Program), and the German-French University (PhD-Track). List of Author signatures, Conference topics, Organization, Conference impressions and list of the participants are available in this PDF.

Meeting report: Vitiligo Global Issues Consensus Conference Workshop "Outcome measurement instruments" and Vitiligo International Symposium, Rome, Nov 30-Dec 3rd

NARCIS (Netherlands)

van Geel, Nanja; Boniface, Katia; Seneschal, Julien; Jacquemin, Clément; Speeckaert, Reinhart; Wolkerstorfer, Albert; Bekkenk, Marcel; Lommerts, Janny E.; Hamzavi, Iltefat; Pandya, Amit; Eleftheriadou, Viktoria; Ezzedine, Khaled; Giannarelli, Diana; Gnarra, Maria; Sperduti, Isabella; Prinsen, Cecilia; Harris, John; Taieb, Alain; Picardo, Mauro

2017-01-01

The international vitiligo community had last December its first "vitiligo only" research meeting in the Eternal City. Vitiligo is a well-recognized but poorly addressed public health concern worldwide. The Vitiligo International Symposium (VIS) is a strong signal for the medical world of the coming

Developing spatial biophysical accounting for multiple ecosystem services

NARCIS (Netherlands)

Remme, R.P.; Schroter, M.; Hein, L.G.

2014-01-01

Ecosystem accounting is receiving increasing interest as a way to systematically monitor the conditions of ecosystems and the ecosystem services they provide. A critical element of ecosystem accounting is understanding spatially explicit flows of ecosystem services. We developed spatial biophysical

Eighth meeting of the International Working Group on Gas-Cooled Reactors Vienna, 30 January - 1 February 1989. Summary report. Part 2

International Nuclear Information System (INIS)

1989-12-01

The Eighth Meeting of the IAEA International Working Group on Gas-Cooled Reactors was held in Vienna, Austria, from 30 January - 1 February, 1989. The Summary Report (Part II) contains the papers which review the national programmes in the field of Gas-Cooled Reactors and other presentations at the Meeting. Refs, figs and tabs

ANNUAL BALI INTERNATIONAL COMBINED CLINICAL MEETING

Directory of Open Access Journals (Sweden)

John Svigos

2015-08-01

Full Text Available Background: This valuable collaboration between Adelaide and Bali was first convened by Prof. I G. Surya, the late Prof. Made Kornia and Associate Prof. John Svigos in May 2011 at Sanglah General Hospital, Bali-Indonesia. This is a three day clinical meeting consisting of a daily Plenary Session for formal presentations running along with a Concurrent Session predominantly for “hands on” and interactive teaching. The meeting has a multidisciplinary focus which is in tune with contemporary Maternal Fetal Medicine practice and consists of obstetricians, midwives, neonatologists and obstetric anaesthetists from both cities sharing their respective experiences. From an initial modest meeting with 80 registrants this has now grown to over 300 registrants in 2015. A fourth day was trialed in 2014 in which a Field Day was incorporated into the program and enabled the overseas participants to gain some first hand experience in the workings of an orphanage (Anak Anak Bali Kids, a midwife obstetric unit (Bumi Sehat and a level two hospital (Sanjiwani Hospital, Gianyar. Further Field Days are anticipated at future meetings. The Visiting Faculty from Australia are predominantly from the Women’s and Children’s Hospital with input from The Lyell McEwin Hospital both in Adelaide, The Royal North Shore Hospital and the Royal Prince Alfred Hospital in Sydney and the King Edward Memorial Hospital in Perth. The broader strategic aspects of the collaboration have seen the rotation of three MFM Trainees from the Trigonum (Denpasar, Surabaya and Malang through Adelaide for two months in 2011 and 2012 as part of their MFM training. Unfortunately AusAID funding has not been forthcoming for further rotations to occur but in 2016 a multidisciplinary group from Sanglah General Hospital will be making a one week visit to the Women’s and Children’s Hospital as a forerunner to further visits. Meantime the collaborations with the Dr. Soetomo Hospital, Surabaya and

Radiation physics, biophysics, and radiation biology. Final report, October 1, 1971--September 30, 1977

International Nuclear Information System (INIS)

Rossi, H.H.; Hall, E.J.

1978-02-01

Research under Contract EY-76-C-02-3243 has been carried out in the area of Radiation Physics, Biophysics and Radiation Biology. During the period of this contract the major accomplishments include, in Physics, the refinement of tissue equivalent dosimetry, the formulation of the concepts of microdosimetry, the development of apparatus used in microdosimetry, and the development of ionization chambers with internal gas multiplication. Principal contributions in Radiobiology have included the determination of RBE and OER as a function of neutron energy, the study of combined effects of radiation and a variety of other agents, and the investigation of the transformation of cells in tissue culture. Theoretical research centered around the development of the theoretical framework of microdosimetry and the establishment of the Theory of Dual Radiation Action. In a cooperative effort with Brookhaven National Laboratory, a major accelerator facility dedicated exclusively to Radiobiology and Radiation Physics, has been developed. Members of the laboratory have performed extensive service to national and international organizations

Evolution and Biophysics of the Escherichia coli lac Operon

Science.gov (United States)

Ray, J. Christian; Igoshin, Oleg; Quan, Selwyn; Monds, Russell; Cooper, Tim; Balázsi, Gábor

2011-03-01

To understand, predict, and control the evolution of living organisms, we consider biophysical effects and molecular network architectures. The lactose utilization system of E. coli is among the most well-studied molecular networks in biology, making it an ideal candidate for such studies. Simulations show how the genetic architecture of the wild-type operon attenuates large metabolic intermediate fluctuations that are predicted to occur in an equivalent system with the component genes on separate operons. Quantification of gene expression in the lac operon evolved in growth conditions containing constant lactose, alternating with glucose, or constant glucose, shows characteristic gene expression patterns depending on conditions. We are simulating these conditions to show context-dependent biophysical sources and costs of different lac operon architectures.

Breast carcinoma during pregnancy. International recommendations from an expert meeting.

Science.gov (United States)

Loibl, Sibylle; von Minckwitz, Gunter; Gwyn, Karin; Ellis, Paul; Blohmer, Jens U; Schlegelberger, Brigitte; Keller, Monika; Harder, Sebastian; Theriault, Richard L; Crivellari, Diana; Klingebiel, Thomas; Louwen, Frank; Kaufmann, Manfred

2006-01-15

Breast carcinoma during pregnancy (BCP) is a difficult clinical situation, as it appears to put the health of the mother in conflict with that of the fetus. An international expert meeting was conducted to form guidelines on how to diagnose and treat women with BCP. The goal for treatment of the pregnant woman with breast carcinoma is the same as that of the nonpregnant breast carcinoma patient: local control of disease and prevention of systemic metastases. However, certain treatment modalities need to be modified because of the potential for adverse effects on the fetus. There is evidence to support the safety of anthracycline-based chemotherapy during the second and third trimesters of pregnancy (Oxford Level of Evidence [LOE] 2b). Because of the lack of evidence, the expert opinion was not to recommend the routine use of newer cytotoxic drugs like the taxanes during pregnancy (LOE 5). The recommendations provided should help to reach informed decision making by the patient. The ongoing prospective collection of data on BCP, such as that at the University of Texas M.D. Anderson Cancer Center (UTMDACC) and that of the German Breast Group/Breast International Group (GBG/BIG), is necessary to further our knowledge regarding the treatment of this unique group of breast carcinoma patients.

78 FR 64260 - U.S. Department of State Advisory Committee on Private International Law (ACPIL): Public Meeting...

Science.gov (United States)

2013-10-28

... International Law (ACPIL): Public Meeting on Cross-Border Insolvency The Office of the Assistant Legal Adviser... potential future work related to cross-border insolvency issues under consideration in the United Nations... has developed a number of instruments related to cross- border insolvency law, including the UNCITRAL...

Introduction to the special issue from the 2014 meeting of the International Behavioral Neuroscience Society.

Science.gov (United States)

Young, Jared W; Hall, F Scott; Pletnikov, Mikhail; Kent, Stephen

2015-11-01

In 2013, President Obama launched what has been optimistically described as the "decade of the brain". The launch of this effort comes on the back of widespread acknowledgement that more is required to aid those suffering from mental health disorders. Specifically, a greater understanding of the neural circuitry related to behaviors specific to mental health disorders is needed. The field of research that relates the circuitry of the brain to specific aspects of behavior is referred to as behavioral neuroscience. The International Behavioral Neuroscience Society (IBNS) was founded in 1992 specifically to meet on an annual basis and present the latest research findings in this field, and to gather together the international research community to discuss issues important for the development and progress of this scientific discipline. This special issue includes reviews of topics of emerging interest and advancing knowledge in behavioral neuroscience, based on symposia presented at the 2014 IBNS meeting. Topics discussed at the annual IBNS meeting ranged from investigations of the neural mechanisms underlying bipolar disorder, schizophrenia, depression, traumatic brain injury, and risk-taking behavior, to behavioral consequences of obesity and immune dysfunction. Novel treatment areas are covered such as the use of deep brain stimulation, as well as investigation of the behavioral impacts of nicotine withdrawal and how this research will influence the development of nicotine cessation treatments. Hence, this special issue covers a wide-range of topics in behavioral neuroscience offering an insight into the challenges faced by researchers in this decade of the brain. Copyright © 2015 Elsevier Ltd. All rights reserved.

Proceedings of the Sixth General Meeting of the International VLBI Service for Geodesy and Astrometry

Science.gov (United States)

Behrend, Dirk (Editor); Baver, Karen D. (Editor)

2010-01-01

This volume is the proceedings of the sixth General Meeting of the International VLBI Service for Geodesy and Astrometry (IVS), held in Hobart, Tasmania, Australia, February 7-13, 2010. The contents of this volume also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/gm2010. The keynote of the sixth GM was the new perspectives of the next generation VLBI system under the theme "VLBI2010: From Vision to Reality". The goal of the meeting was to provide an interesting and informative program for a wide cross-section of IVS members, including station operators, program managers, and analysts. This volume contains 88 papers. All papers were edited by the editors for usage of the English language, form, and minor content-related issues.

Materials of 4. international meeting on pulse investigations in physics, chemistry and biology. PULS'94

International Nuclear Information System (INIS)

1994-01-01

4. International Meeting on Pulse Investigations in Physics, Chemistry and Biology, PULS'94 has been organized in honor of Professor Jerzy Kroh, the precursor of radiation chemistry in Poland. The meeting has been divided into three sessions: the historical session (H) with four review lectures, lecture session (L) collected 23 papers and poster session (P) with 39 posters. The fundamental studies on early stages of radiolysis have been presented for different systems being irradiated. The pulse radiolysis and flash photolysis methods has been predominantly used in reported experimental works. The reaction of intermediate products of radiolysis and photolysis such a trapped and solvated electrons, ions and radicals has been extensively studied. The reaction mechanisms and kinetics have been also discussed

Direct Scaling of Leaf-Resolving Biophysical Models from Leaves to Canopies

Science.gov (United States)

Bailey, B.; Mahaffee, W.; Hernandez Ochoa, M.

2017-12-01

Recent advances in the development of biophysical models and high-performance computing have enabled rapid increases in the level of detail that can be represented by simulations of plant systems. However, increasingly detailed models typically require increasingly detailed inputs, which can be a challenge to accurately specify. In this work, we explore the use of terrestrial LiDAR scanning data to accurately specify geometric inputs for high-resolution biophysical models that enables direct up-scaling of leaf-level biophysical processes. Terrestrial LiDAR scans generate "clouds" of millions of points that map out the geometric structure of the area of interest. However, points alone are often not particularly useful in generating geometric model inputs, as additional data processing techniques are required to provide necessary information regarding vegetation structure. A new method was developed that directly reconstructs as many leaves as possible that are in view of the LiDAR instrument, and uses a statistical backfilling technique to ensure that the overall leaf area and orientation distribution matches that of the actual vegetation being measured. This detailed structural data is used to provide inputs for leaf-resolving models of radiation, microclimate, evapotranspiration, and photosynthesis. Model complexity is afforded by utilizing graphics processing units (GPUs), which allows for simulations that resolve scales ranging from leaves to canopies. The model system was used to explore how heterogeneity in canopy architecture at various scales affects scaling of biophysical processes from leaves to canopies.

Synthesis of the expert group meetings convened as part of the substantive preparations for the International Conference on Population and Development.

Science.gov (United States)

1993-01-01

As part of the preparation for the 1994 International Conference on Population and Development to be sponsored by the UN in Cairo, 6 expert groups were convened to consider 1) population growth; 2) population policies and programs; 3) population, development, and the environment; 4) migration; 5) the status of women; and 6) family planning programs, health, and family well-being. Each group included 15 experts representing a full range of relevant scientific disciplines and geographic regions. Each meeting lasted 5 days and included a substantive background paper prepared by the Population Division as well as technical papers. Each meeting concluded with the drafting of between 18 and 37 recommendations (a total of 162). The meeting on population, the environment, and development focused on the implications of current trends in population and the environment for sustained economic growth and sustainable development. The meeting on population policies and programs observed that, since 1984, there has been a growing convergence of views about population growth among the nations of the world and that the stabilization of world population as soon as possible is now an internationally recognized goal. The group on population and women identified practical steps that agencies could take to empower women in order to achieve beneficial effects on health, population trends, and development. The meeting on FP, health, and family well-being reviewed policy-oriented issues emerging from the experience of FP programs. The meeting on population growth and development reviewed trends and prospects of population growth and age structure and their consequences for global sustainability. The population distribution and migration experts appraised current trends and their interrelationship with development. In nearly all of the group meetings, common issues emerged. Concern was universally voiced for sustainable development and sustained economic growth, relevance of past experience

A quantitative overview of biophysical forces impinging on neural function

International Nuclear Information System (INIS)

Mueller, Jerel K; Tyler, William J

2014-01-01

The fundamentals of neuronal membrane excitability are globally described using the Hodgkin-Huxley (HH) model. The HH model, however, does not account for a number of biophysical phenomena associated with action potentials or propagating nerve impulses. Physical mechanisms underlying these processes, such as reversible heat transfer and axonal swelling, have been compartmentalized and separately investigated to reveal neuronal activity is not solely influenced by electrical or biochemical factors. Instead, mechanical forces and thermodynamics also govern neuronal excitability and signaling. To advance our understanding of neuronal function and dysfunction, compartmentalized analyses of electrical, chemical, and mechanical processes need to be revaluated and integrated into more comprehensive theories. The present perspective is intended to provide a broad overview of biophysical forces that can influence neural function, but which have been traditionally underappreciated in neuroscience. Further, several examples where mechanical forces have been shown to exert their actions on nervous system development, signaling, and plasticity are highlighted to underscore their importance in sculpting neural function. By considering the collective actions of biophysical forces influencing neuronal activity, our working models can be expanded and new paradigms can be applied to the investigation and characterization of brain function and dysfunction. (topical review)

Status of National Programmes on Fast Breeder Reactors. International Working Group on Fast Reactors, Twentieth Annual Meeting, Vienna, 24-27 March 1987

International Nuclear Information System (INIS)

1987-07-01

The Agenda of the meeting was as follows: 1. Approval of the Agenda. 2. Approval of the minutes of the 19th meeting of the IWGFR. 3. Report of the Scientific Secretary regarding the WD activities of the Working Group. 4. Presentations and discussions on national programmes on fast breeder reactors. 5. Consideration of conferences on fast breeder reactors. a. ANS-ENS International Conference on Fast Breeder Systems Experience Gained and Path to Economical Power Generation, Richland, Washington, USA, 13-17 September 1987. b. International Conference on Liquid Metal Engineering and Technology, Avignon, France, 17-20 October 1988. c. Other meetings of interest to IWGFR members. 6. Consideration of major recommendations of some of the WD IWGFR Specialists' Meetings. 7. Consideration of arrangements for Specialists' Meetings in 1987. a. Specialists' Meeting on Fission and Corrosion Products Behaviour in Primary Circuits of LMFBRs, Karlsruhe, Fed. Rep. of Germany, May 1987. b. Specialists' Meeting on LMFBR Reactor Block Antiseismic Design and Verification, Bologna, Italy, October 1987. 8. Selection of topics for Specialists' Meetings to be held in 1988 and suggestions of the IWGFR on other Specialists' Meetings and their justifications. 9. Consideration of joint research activities: a. Coordinated Research Programme on a Comparative Assessment of Processing Techniques for Analysis of Sodium Boiling Noise Detection Data. b. Coordinated Research Programme on Intercomparison of LMFBR Core Mechanics Codes. c. New Topics of CRP. d. Other Activities. 10. Updating of ''LMFBR Plant Parameters''. 11. Informal discussion on ''Safety Criteria for Fast Reactors in IWGFR Countries''. 12. The date and place of the 21th Annual Meeting of the IWGFR

Biophysical characteristics reveal neural stem cell differentiation potential.

Directory of Open Access Journals (Sweden)

Fatima H Labeed

Full Text Available Distinguishing human neural stem/progenitor cell (huNSPC populations that will predominantly generate neurons from those that produce glia is currently hampered by a lack of sufficient cell type-specific surface markers predictive of fate potential. This limits investigation of lineage-biased progenitors and their potential use as therapeutic agents. A live-cell biophysical and label-free measure of fate potential would solve this problem by obviating the need for specific cell surface markers.We used dielectrophoresis (DEP to analyze the biophysical, specifically electrophysiological, properties of cortical human and mouse NSPCs that vary in differentiation potential. Our data demonstrate that the electrophysiological property membrane capacitance inversely correlates with the neurogenic potential of NSPCs. Furthermore, as huNSPCs are continually passaged they decrease neuron generation and increase membrane capacitance, confirming that this parameter dynamically predicts and negatively correlates with neurogenic potential. In contrast, differences in membrane conductance between NSPCs do not consistently correlate with the ability of the cells to generate neurons. DEP crossover frequency, which is a quantitative measure of cell behavior in DEP, directly correlates with neuron generation of NSPCs, indicating a potential mechanism to separate stem cells biased to particular differentiated cell fates.We show here that whole cell membrane capacitance, but not membrane conductance, reflects and predicts the neurogenic potential of human and mouse NSPCs. Stem cell biophysical characteristics therefore provide a completely novel and quantitative measure of stem cell fate potential and a label-free means to identify neuron- or glial-biased progenitors.

40 CFR 60.4203 - How long must my engines meet the emission standards if I am a stationary CI internal combustion...

Science.gov (United States)

2010-07-01

... emission standards if I am a stationary CI internal combustion engine manufacturer? 60.4203 Section 60.4203... Combustion Engines Emission Standards for Manufacturers § 60.4203 How long must my engines meet the emission standards if I am a stationary CI internal combustion engine manufacturer? Engines manufactured by...

Biochemical and Biophysical Cues in Matrix Design for Chronic and Diabetic Wound Treatment.

Science.gov (United States)

Xiao, Yun; Ahadian, Samad; Radisic, Milica

2017-02-01

Progress in biomaterial science and engineering and increasing knowledge in cell biology have enabled us to develop functional biomaterials providing appropriate biochemical and biophysical cues for tissue regeneration applications. Tissue regeneration is particularly important to treat chronic wounds of people with diabetes. Understanding and controlling the cellular microenvironment of the wound tissue are important to improve the wound healing process. In this study, we review different biochemical (e.g., growth factors, peptides, DNA, and RNA) and biophysical (e.g., topographical guidance, pressure, electrical stimulation, and pulsed electromagnetic field) cues providing a functional and instructive acellular matrix to heal diabetic chronic wounds. The biochemical and biophysical signals generally regulate cell-matrix interactions and cell behavior and function inducing the tissue regeneration for chronic wounds. Some technologies and devices have already been developed and used in the clinic employing biochemical and biophysical cues for wound healing applications. These technologies can be integrated with smart biomaterials to deliver therapeutic agents to the wound tissue in a precise and controllable manner. This review provides useful guidance in understanding molecular mechanisms and signals in the healing of diabetic chronic wounds and in designing instructive biomaterials to treat them.

Biophysical models of radiobiological effects

International Nuclear Information System (INIS)

Obaturov, G.M.

1987-01-01

Radiobiological effect models at different organization levels, developed by the author, are presented. Classification and analysis of concepts and biophysical models at molecular, genetic and cellular levels, developed by Soviet and foreign authors in comparison to inherent models, are conducted from the viewpoint of system approach to radiobiological processes and of modelling principles. Models are compared with each other, limits of their applicability and drawbacks are determined. Evaluation of the model truthfulness is conducted according to a number of criteria, ways of further investigations and experimental examination of some models are proposed

Clostridium XIV Meeting

Energy Technology Data Exchange (ETDEWEB)

Lynd, Lee

2016-08-28

The 14th biannual Clostridium meeting was held at Dartmouth College from August 28 through 31, 2016. As noted in the meeting program (http://clostridiumxiv.com/wp-content/uploads/2016/09/Clostridium_XIV_program.pdf). the meeting featured 119 registered attendees, 33 oral presentations, 5 of which were given by younger presenters, 40 posters, and 2 keynote presentations, with strong participation by female and international scientists.

Biophysics of DNA

CERN Document Server

Vologodskii, Alexander

2015-01-01

Surveying the last sixty years of research, this book describes the physical properties of DNA in the context of its biological functioning. It is designed to enable both students and researchers of molecular biology, biochemistry and physics to better understand the biophysics of DNA, addressing key questions and facilitating further research. The chapters integrate theoretical and experimental approaches, emphasising throughout the importance of a quantitative knowledge of physical properties in building and analysing models of DNA functioning. For example, the book shows how the relationship between DNA mechanical properties and the sequence specificity of DNA-protein binding can be analyzed quantitatively by using our current knowledge of the physical and structural properties of DNA. Theoretical models and experimental methods in the field are critically considered to enable the reader to engage effectively with the current scientific literature on the physical properties of DNA.

Status of national programmes on fast reactors 1997/98. 31. annual meeting of the International Working Group on Fast Reactors

International Nuclear Information System (INIS)

1998-01-01

The objective of the meeting was to co-ordinate the exchange of information on the status of fast reactor development and operational experience, including experience with experimental types of reactor; to consider meeting arrangements for 1998 and 1999; and to review the IAEA co-ordinated research activities in the field of fast reactor, as well as co-ordination of the International Working Group on Fast Reactors activities with other organizations

HEPLIB '91: International users meeting on the support and environments of high energy physics computing

International Nuclear Information System (INIS)

Johnstad, H.

1991-01-01

The purpose of this meeting is to discuss the current and future HEP computing support and environments from the perspective of new horizons in accelerator, physics, and computing technologies. Topics of interest to the Meeting include (but are limited to): the forming of the HEPLIB world user group for High Energy Physic computing; mandate, desirables, coordination, organization, funding; user experience, international collaboration; the roles of national labs, universities, and industry; range of software, Monte Carlo, mathematics, physics, interactive analysis, text processors, editors, graphics, data base systems, code management tools; program libraries, frequency of updates, distribution; distributed and interactive computing, data base systems, user interface, UNIX operating systems, networking, compilers, Xlib, X-Graphics; documentation, updates, availability, distribution; code management in large collaborations, keeping track of program versions; and quality assurance, testing, conventions, standards

Scientific meetings

International Nuclear Information System (INIS)

1973-01-01

One of the main aims of the IAEA is to foster the exchange of scientific and technical information and one of the main ways of doing this is to convene international scientific meetings. They range from large international conferences bringing together several hundred scientists, smaller symposia attended by an average of 150 to 250 participants and seminars designed to instruct rather than inform, to smaller panels and study groups of 10 to 30 experts brought together to advise on a particular programme or to develop a set of regulations. The topics of these meetings cover every part of the Agency's activities and form a backbone of many of its programmes. (author)

Biophysical approach to low back pain: a pilot report

Czech Academy of Sciences Publication Activity Database

Foletti, A.; Pokorný, Jiří

2015-01-01

Roč. 34, č. 2 (2015), s. 156-159 ISSN 1536-8378 Institutional support: RVO:67985882 Keywords : Bioelectromagnetic medicine * Biophysical therapy * Coherence domains Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 1.208, year: 2015

Summary Report of an IAEA Technical Meeting on Co-ordination of the International Network of Nuclear Structure and Decay Data Evaluators

Energy Technology Data Exchange (ETDEWEB)

Abriola, D [IAEA Nuclear Data Section, Vienna (Austria); Nichols, A L [Departments of Physics, University of Surrey, Guildford (United Kingdom); Tuli, J K [Brookhaven National Laboratory, Brookhaven, Upton, NY (United States)

2011-10-15

The 19th meeting of the International Network of Nuclear Structure and Decay Data Evaluators was convened at the IAEA Headquarters, Vienna, from 4 to 8 April 2011, by the staff members of IAEA, Nuclear Data Section. This meeting was attended by 35 scientists from 20 Member States, plus IAEA staff, concerned with the compilation, evaluation and dissemination of nuclear structure and decay data. A summary of the meeting, data centre reports, various proposals considered, modified and agreed by the participants, and recommendations/conclusions are presented within this document. (author)

Summary Report of an IAEA Technical Meeting on Co-ordination of the International Network of Nuclear Structure and Decay Data Evaluators

International Nuclear Information System (INIS)

Abriola, D.; Nichols, A.L.; Tuli, J.K.

2011-10-01

The 19th meeting of the International Network of Nuclear Structure and Decay Data Evaluators was convened at the IAEA Headquarters, Vienna, from 4 to 8 April 2011, by the staff members of IAEA, Nuclear Data Section. This meeting was attended by 35 scientists from 20 Member States, plus IAEA staff, concerned with the compilation, evaluation and dissemination of nuclear structure and decay data. A summary of the meeting, data centre reports, various proposals considered, modified and agreed by the participants, and recommendations/conclusions are presented within this document. (author)

75 FR 73166 - Art Advisory Panel-Closed Meeting

Science.gov (United States)

2010-11-29

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of Closed Meeting of Art Advisory Panel for Decorative Art. SUMMARY: A closed meeting of the Art Advisory Panel will be held in Washington, DC. DATES: The...

Theoretical molecular biophysics

CERN Document Server

Scherer, Philipp O J

2017-01-01

This book gives an introduction to molecular biophysics. It starts from material properties at equilibrium related to polymers, dielectrics and membranes. Electronic spectra are developed for the understanding of elementary dynamic processes in photosynthesis including proton transfer and dynamics of molecular motors. Since the molecular structures of functional groups of bio-systems were resolved, it has become feasible to develop a theory based on the quantum theory and statistical physics with emphasis on the specifics of the high complexity of bio-systems. This introduction to molecular aspects of the field focuses on solvable models. Elementary biological processes provide as special challenge the presence of partial disorder in the structure which does not destroy the basic reproducibility of the processes. Apparently the elementary molecular processes are organized in a way to optimize the efficiency. Learning from nature by means exploring the relation between structure and function may even help to b...

Biophysical dosimetry using electron paramagnetic resonance in human tooth

International Nuclear Information System (INIS)

Khan, R.F.H.; Boreham, D.R.; Rink, W.J.

2002-01-01

Accidental dosimetry utilizing radiation induced paramagnetic species in biophysical tissues like teeth is a technique; that can measure the amount of radiation exposure to an individual. The major problem in implementing this technique at low doses is the presence of native organic signal, and various other artifacts produced as a result of sample processing. After a series of experimental trials, we developed an optimum set of rules, which uses high temperature ultrasonic treatment of enamel in KOH, multiple sample rotation during in-cavity measurement of natural and calibrated added irradiations, and dose construction using a backward extrapolation method. By using this we report the successful dose reconstruction in a few of our laboratory samples in 100 mGy range (76.29 ± 30.14) mGy with reasonably low uncertainty. Keywords: biophysical dosimetry, human tooth enamel, low dose measurements, accidental dosimetry (author)

Radiobiology, biochemistry and radiation biophysics at CYLAB

International Nuclear Information System (INIS)

Ftacnikova, S.

1998-01-01

The Cyclotron Laboratory (CYLAB) should fill the gap in the field of nuclear medicine, radiotherapy, basic research, metrology of ionizing radiation, education and implications of accelerator technology existing today in Slovak Republic. The main planned activities of this facility are in the fields of nuclear medicine (production of radioisotopes for Positron Emission Tomography - PET and for oncology) and radiotherapy (neutron capture therapy, fast neutron therapy and proton therapy). The radiobiological and biophysical research will be closely connected with medical applications, particularly with radiotherapy. Problems to be addressed include the determination of the values of Relative Biological Effectiveness (RBE) for different types of ionizing radiation involved in the therapy, microdosimetric measurements and calculations, which are indispensable in the calculation of the absorbed dose (lineal and specific energy spectra) at the cellular and macromolecular level. Radiation biophysics and medical physics help in creating therapeutic plans for radiotherapy (NCT and fast neutron therapy). In nuclear medicine, in diagnostic and therapeutical procedures it is necessary to assess the biodistribution of radiopharmaceuticals and to calculate doses in target and critical organs and to determine whole body burden - effective equivalent dose for newly developed radiopharmaceuticals

International meeting 'Selected topics on nuclear methods for non-nuclear applications'. Proceedings

International Nuclear Information System (INIS)

Stoyanov, Ch.

2007-01-01

The volume includes the presentations given on the International Meeting 'Selected Topics on Nuclear Methods for Non-nuclear Applications'. The meeting was organized by the Project CECOA. The Project 'CEnter for COoerative Activities' (CECOA) of the Institute for Nuclear Research and Nuclear Energy (INRNE) of Bulgarian Academy of Sciences is part of the Program 'Creating of Infrastructure' of Bulgarian Ministry of Science and Education. The CECOA-project unifies the groups of INRNE doing research in the field of nuclear methods. Four Laboratories of INRNE are members of CECOA-project: Moessbauer Spectroscopy and Low Radioactivity Measurements, High-Resolution Gamma-Spectroscopy, Neutron Methods in Condensed Matter, Neutron Optics and Structure Analysis. Taking into account the leading role of education on nuclear physics the Project includes program devoted to the training on nuclear physics. The presented volume contains 23 contributed papers. The contributions are separated in 6 sections. The section 'Nano technology' includes 5 papers. The activity in this field within the Project reveals the collaboration with other Institutes of Bulgarian Academy of Sciences as well as large international contacts. The section 'Radioecology and Radioactive Waste' is two fold. Part of the contributions of the section manifests the connection of the CECOA with small enterprises. The contacts are on the level of common projects concerning the investigations, remediation and release of radioactively contaminated terrain, soils, water, buildings and materials around the former uranium processing industry. Another part of the section is devoted to the application of nuclear methods to the treatment of radioactive waste produced by nuclear power stations. The section 'Neutron Physics' reveals the activity within the Project connected with the study of new materials using polarized neutrons and neutron diffraction methods. The section 'Nuclear Physics' is an introduction to some

Meeting of senior officials on managing nuclear knowledge. Meeting report

International Nuclear Information System (INIS)

2002-01-01

In response to the recommendations of several Agency advisory committees, e.g. INSAG, SAGNE 2002, SAGNA, SAGTAC, to address issues related to nuclear knowledge management, the IAEA convened a meeting on Managing Nuclear Knowledge with senior representatives from Member States. The purpose of the meeting was to sharpen awareness and understanding of the emerging concerns about the maintenance and preservation of knowledge and expertise in nuclear science, technology and applications and to better comprehend the role of the Agency in this process. The meeting was attended by more than 70 participants from 35 Member States and 4 international organizations, representing academic leaders, senior level executives, managers and governmental officials. This report includes general recommendations, summary of the keynote of the Member States, statements on the role of the IAEA and International cooperation in managing nuclear knowledge

Analysis of Reactive Oxygen Species Production and Myeloperoxidase Activity in Chemically Induced Differentiation of Human Myeloid Leukemia Cells

Czech Academy of Sciences Publication Activity Database

Souček, Karel; Kubala, Lukáš; Lojek, Antonín; Kozubík, Alois

2000-01-01

Roč. 46, - (2000), s. 420 ISSN 1433-6510. [International Meeting - Fundamentals and Applications of Modern Chemi- and Bioluminescence Research in Chemistry, Biochemistry, Medicine and Education . Dresden, 10.05.2000-13.05.2000] Institutional research plan: CEZ:AV0Z5004920 Subject RIV: BO - Biophysics

Ultrasound assessment of the fetal biophysical profile: What does an radiologist need to know?

International Nuclear Information System (INIS)

Guimaraes Filho, Helio Antonio; Araujo Junior, Edward; Marcondes Machado Nardozza, Luciano; Linhares Dias da Costa, Lavoisier; Fernandes Moron, Antonio; Mattar, Rosiane

2008-01-01

Proposed by Frank Manning about 26 years ago, fetal biophysical profile has been incorporated to the propaedeutics of non-invasive fetal well being assessment in high-risk gestations. Despite the existence of other methods for assessing fetal vitality, as Doppler flowmetry, the biophysical profile continues to be important in estimating the risk of hypoxia and perinatal morbimortality for those fetuses. In the present article, the authors review the regulatory mechanisms of fetal biophysical activities, as well as physiological and pathological factors that interfere with them. The main objective of the study is to discuss the present and important aspects of the method, and the practical applications and interpretation of its findings, in order to help radiologists improve their knowledge in this specific area of fetal ultrasonography

Twenty-eighth Meeting of the Working Party on International Nuclear Data Evaluation Co-operation. Summary Record

International Nuclear Information System (INIS)

Chadwick, Mark; ); Danon, Yaron; Herman, Mike; ); Dunn, Mike; ); Kahler, Albert Skip; ); Jacqmin, Robert; ); Plompen, Arjan; ); Fukahori, Tokio; ); Harada, Hideo; ); Iwamoto, Osamu; Yokoyama, Kenji; ); Grudzevich, Oleg; ); Ge, Zhigang; Ruan, Xichao; Wu, Haicheng; Koning, Arjan; ); Mills, Robert; ); Mcnabb, Dennis; ); Palmiotti, Giuseppe; ); Noguere, Gilles; ); Leal, Luiz; ); Cabellos, Oscar; )

2016-01-01

The NEA's nuclear data evaluation co-operation activities involve the following evaluation projects: ENDF (United States), JENDL (Japan), ROSFOND/BROND (Russia), JEFF (other Data Bank member countries) and CENDL (China) in close co-operation with the Nuclear Data Section of the International Atomic Energy Agency (IAEA). The working party was established to promote the exchange of information on nuclear data evaluations, measurements, nuclear model calculations, validation, and related topics, and to provide a framework for cooperative activities between the participating projects. The working party assesses nuclear data improvement needs and addresses these needs by initiating joint evaluation and/or measurement efforts. The 28. Meeting of the WPEC was the occasion to review the experimental activities, the evaluation projects and the Status of subgroups. This document is the summary record of the meeting. It presents: 1 - The reports on experimental activities: Experimental nuclear data activities of relevance to the evaluation projects were reviewed. Detailed information about the experimental activities is given in the reports and view-graphs presented at the meeting. 2 - The review of final or near-final subgroup reports. Results and conclusions of completed or near-completed subgroups were discussed. A summary table of all subgroup status is given in Annex 3. 3 - The status of ongoing subgroups. Activities of ongoing subgroups were presented. A summary table of all subgroup status is given in Annex 3. 4 - The proposals for new subgroups. The subgroup proposal was reviewed by WPEC. Detailed information about this proposal is given in the document. 5 - The forthcoming meetings of interest. The documents presented at the twenty-eight WPEC meeting are presented in the annex 2: Annex 2.1 Working Party on International Nuclear Data Evaluation Co-operation - WPEC; Annex 2.2 WPEC Long-term mandate (updated and extended) on a 'Expert Group on the High Priority Request

A biophysical approach to the optimisation of dendritic-tumour cell electrofusion

International Nuclear Information System (INIS)

Sukhorukov, Vladimir L.; Reuss, Randolph; Endter, Joerg M.; Fehrmann, Steffen; Katsen-Globa, Alisa; Gessner, Petra; Steinbach, Andrea; Mueller, Kilian J.; Karpas, Abraham; Zimmermann, Ulrich; Zimmermann, Heiko

2006-01-01

Electrofusion of tumour and dendritic cells (DCs) is a promising approach for production of DC-based anti-tumour vaccines. Although human DCs are well characterised immunologically, little is known about their biophysical properties, including dielectric and osmotic parameters, both of which are essential for the development of efficient electrofusion protocols. In the present study, human DCs from the peripheral blood along with a tumour cell line used as a model fusion partner were examined by means of time-resolved cell volumetry and electrorotation. Based on the biophysical cell data, the electrofusion protocol could be rapidly optimised with respect to the sugar composition of the fusion medium, duration of hypotonic treatment, frequency range for stable cell alignment, and field strengths of breakdown pulses triggering membrane fusion. The hypotonic electrofusion consistently gave a tumour-DC hybrid rate of up to 19%, as determined by counting dually labelled fluorescent hybrids in a microscope. This fusion rate is nearly twice as high as that usually reported in the literature for isotonic media. The experimental findings and biophysical approach presented here are generally useful for the development of efficient electrofusion protocols, especially for rare and valuable human cells

EDITORIAL: Special issue containing contributions from the Fourth International Brain-Computer Interface Meeting Special issue containing contributions from the Fourth International Brain-Computer Interface Meeting

Science.gov (United States)

Vaughan, Theresa M.; Wolpaw, Jonathan R.

2011-04-01

This special issue of Journal of Neural Engineering is a result of the Fourth International Brain-Computer Interface Meeting, which was held at the Asilomar Conference Center in Monterey, California, USA from 31 May to 4 June, 2010. The meeting was sponsored by the National Institutes of Health, The National Science Foundation and the Department of Defense, and was organized by the Wadsworth Center of the New York State Department of Health. It attracted over 260 participants from 17 countries—including many graduate students and postdoctoral fellows—and featured 19 workshops, platform presentations from 26 research groups, 170 posters, multiple brain-computer interface (BCI) demonstrations, and a keynote address by W Zev Rymer of the Rehabilitation Institute of Chicago. The number of participants and the diversity of the topics covered greatly exceeded those of the previous meeting in 2005, and testified to the continuing rapid expansion and growing sophistication of this exciting and still relatively new research field. BCI research focuses primarily on using brain signals to replace or restore the motor functions that people have lost due to amyotrophic lateral sclerosis (ALS), a brainstem stroke, or some other devastating neuromuscular disorder. In the last few years, attention has also turned towards using BCIs to improve rehabilitation after a stroke, and beyond that to enhancing or supplementing the capabilities of even those without disabilities. These diverse interests were represented in the wide range of topics covered in the workshops. While some workshops addressed broad traditional topics, such as signal acquisition, feature extraction and translation, and software development, many addressed topics that were entirely new or focused sharply on areas that have become important only recently. These included workshops on optimizing P300-based BCIs; improving the mutual adaptations of the BCI and the user; BCIs that can control neuroprostheses

Seminal Fluid Analysis And Biophysical Profile: Findings And ...

African Journals Online (AJOL)

Seminal Fluid Analysis And Biophysical Profile: Findings And Relevance In Infertile Males In Ilorin, Nigeria. EK Oghagbon, AAG Jimoh, SA Adebisi. Abstract. To determine if there was a bearing of body mass index (BMI) on male infertility, a cross-sectional study of males of infertile couples, attending our infertility clinic was ...

Representing biophysical landscape interactions in soil models by bridging disciplines and scales.

Science.gov (United States)

van der Ploeg, M. J.; Carranza, C.; Teixeira da Silva, R.; te Brake, B.; Baartman, J.; Robinson, D.

2017-12-01

The combination of climate change, population growth and soil threats including carbon loss, biodiversity decline and erosion, increasingly confront the global community (Schwilch et al., 2016). One major challenge in studying processes involved in soil threats, landscape resilience, ecosystem stability, sustainable land management and resulting economic consequences, is that it is an interdisciplinary field (Pelletier et al., 2012). Less stringent scientific disciplinary boundaries are therefore important (Liu et al., 2007), because as a result of disciplinary focus, ambiguity may arise on the understanding of landscape interactions. This is especially true in the interaction between a landscape's physical and biological processes (van der Ploeg et al. 2012). Biophysical landscape interactions are those biotic and abiotic processes in a landscape that have an influence on the developments within and evolution of a landscape. An important aspect in biophysical landscape interactions is the differences in scale related to the various processes that play a role in these systems. Moreover, the interplay between the physical landscape and the occurring vegetation, which often co-evolve, and the resulting heterogeneity and emerging patterns are the reason why it is so challenging to establish a theoretical basis to describe biophysical processes in landscapes (e.g. te Brake et al. 2013, Robinson et al. 2016). Another complicating factor is the response of vegetation to changing environmental conditions, including a possible, and often unknown, time-lag (e.g. Metzger et al., 2009). An integrative description for modelling biophysical interactions has been a long standing goal in soil science (Vereecken et al., 2016). We need the development of soil models that are more focused on networks, connectivity and feedbacks incorporating the most important aspects of our detailed mechanistic modelling (Paola & Leeder, 2011). Additionally, remote sensing measurement techniques

Proceedings of the 10th international topical meeting on nuclear thermal hydraulics, operation and safety (NUTHOS-10)

International Nuclear Information System (INIS)

2014-01-01

The 10th International Topical Meeting on Nuclear Thermal Hydraulics, Operations and Safety (NUTHOS-10) in Okinawa, Japan is sponsored by Atomic Energy Society of Japan, in cooperation with the International Atomic Energy Agency, and co-sponsored by American Nuclear Society Thermal Hydraulics Division among others. Enhanced safety and reducing cost are going together, which can be achieved through continued research and development efforts. NUTHOS keeps you abreast of the most updated information in the advancement of science and technology in nuclear thermal hydraulics, operations and safety, and provides you insights into the future. (J.P.N.)

International Working Group on Fast Reactors. Meeting of Specialists on the Value of Plutonium Alpha, Winfrich, UK, 30 June - 1 July 1969. Summary Report

Energy Technology Data Exchange (ETDEWEB)

NONE

1969-07-15

The meeting of specialists on the value of plutonium alpha was held at Winfrith in accordance to the recommendation of the International Working Group on Fast Reactors, and in agreement with the UK authorities. Participants from six countries and two international organizations took part in the meeting. A short review on available data for plutonium alpha received by the IAEA Nuclear Data Unit was presented. Three experiments recently known where the measurements of the alpha-value have been made in the energy range of interest were referred to.

Remote sensing of the Canadian Arctic: Modelling biophysical variables

Science.gov (United States)

Liu, Nanfeng

It is anticipated that Arctic vegetation will respond in a variety of ways to altered temperature and precipitation patterns expected with climate change, including changes in phenology, productivity, biomass, cover and net ecosystem exchange. Remote sensing provides data and data processing methodologies for monitoring and assessing Arctic vegetation over large areas. The goal of this research was to explore the potential of hyperspectral and high spatial resolution multispectral remote sensing data for modelling two important Arctic biophysical variables: Percent Vegetation Cover (PVC) and the fraction of Absorbed Photosynthetically Active Radiation (fAPAR). A series of field experiments were conducted to collect PVC and fAPAR at three Canadian Arctic sites: (1) Sabine Peninsula, Melville Island, NU; (2) Cape Bounty Arctic Watershed Observatory (CBAWO), Melville Island, NU; and (3) Apex River Watershed (ARW), Baffin Island, NU. Linear relationships between biophysical variables and Vegetation Indices (VIs) were examined at different spatial scales using field spectra (for the Sabine Peninsula site) and high spatial resolution satellite data (for the CBAWO and ARW sites). At the Sabine Peninsula site, hyperspectral VIs exhibited a better performance for modelling PVC than multispectral VIs due to their capacity for sampling fine spectral features. The optimal hyperspectral bands were located at important spectral features observed in Arctic vegetation spectra, including leaf pigment absorption in the red wavelengths and at the red-edge, leaf water absorption in the near infrared, and leaf cellulose and lignin absorption in the shortwave infrared. At the CBAWO and ARW sites, field PVC and fAPAR exhibited strong correlations (R2 > 0.70) with the NDVI (Normalized Difference Vegetation Index) derived from high-resolution WorldView-2 data. Similarly, high spatial resolution satellite-derived fAPAR was correlated to MODIS fAPAR (R2 = 0.68), with a systematic

12th Quadrennial Congress of the International Association for Radiation Research incorporating the 50th Annual Meeting of Radiation Research Society, RANZCR Radiation Oncology Annual Scientific Meeting and AINSE Radiation Science Conference

International Nuclear Information System (INIS)

2003-01-01

The 12th International Congress of Radiation Research (ICRR2003), for the first time held in the Southern Hemisphere under the auspices of the International Association of Radiation Research (IARR). The Australian affiliate of IARR is the Australian Institute of Nuclear Science and Engineering (AINSE). As with recent Congresses, the annual scientific meeting of the Radiation Research Society will be incorporated into the program. The Congress will be further enhanced by the integration of the annual scientific meeting of the Faculty of Radiation Oncology of the Royal Australian and New Zealand College of Radiologists, and the AINSE Radiation Science Conference. An exciting programme was presented with the main threads being radiation oncology, radiation biology, radiation chemistry/physics, radiation protection and the environment. Items in INIS scope have been separately indexed

International working group on life management of nuclear power plants (IWG-LMNPP). Regular meeting. 30 August - 1 September 1995. Working material. V. 2

International Nuclear Information System (INIS)

1995-01-01

This meeting of the International Working Group on Life Management of Nuclear Power Plants (IWG-LMNPP) was organized to review the national programmes of the countries and to advise the IAEA on its technical meetings and activities in the subject areas taking into consideration current progress, problems and operating experience. Refs, figs and tabs

International working group on life management of nuclear power plants (IWG-LMNPP). Regular meeting. 30 August - 1 September 1995. Working material. V. 1

International Nuclear Information System (INIS)

1995-01-01

This meeting of the International Working Group on Life Management of Nuclear Power Plants (IWG-LMNPP) was organized to review the national programmes of the countries and to advise the IAEA on its technical meetings and activities in the subject areas taking into consideration current progress, problems and operating experience. Refs, figs and tabs

Biophysical constraints on leaf expansion in a tall conifer.

Science.gov (United States)

Fredrick C. Meinzer; Barbara J. Bond; Jennifer A. Karanian

2008-01-01

The physiological mechanisms responsible for reduced extension growth as trees increase in height remain elusive. We evaluated biophysical constraints on leaf expansion in old-growth Douglas-fir (Psuedotsuga menziesii (Mirb.) Franco) trees. Needle elongation rates, plastic and elastic extensibility, bulk leaf water, (L...

75 FR 22437 - Art Advisory Panel-Notice of Closed Meeting

Science.gov (United States)

2010-04-28

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of Closed Meeting of Art Advisory Panel. SUMMARY: Closed meeting of the Art Advisory Panel will be held in Washington, DC. DATES: The meeting will...

76 FR 30243 - Art Advisory Panel-Notice of Closed Meeting

Science.gov (United States)

2011-05-24

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of closed meeting of Art Advisory Panel. SUMMARY: Closed meeting of the Art Advisory Panel will be held in Washington, DC. DATES: The meeting will...

78 FR 32307 - Art Advisory Panel-Notice of Closed Meeting

Science.gov (United States)

2013-05-29

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of closed meeting of Art Advisory Panel. SUMMARY: Closed meeting of the Art Advisory Panel will be held in Baltimore, MD. DATES: The meeting will...

75 FR 1684 - Art Advisory Panel-Notice of Closed Meeting

Science.gov (United States)

2010-01-12

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of Closed Meeting of Art Advisory Panel. SUMMARY: Closed meeting of the Art Advisory Panel will be held in Washington, DC. DATES: The meeting will...

75 FR 19465 - Art Advisory Panel-Notice of Closed Meeting

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2010-04-14

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of closed meeting of Art Advisory Panel. SUMMARY: Closed meeting of the Art Advisory Panel will be held in Washington, DC. DATES: The meeting will...

78 FR 73586 - Art Advisory Panel-Notice of Closed Meeting

Science.gov (United States)

2013-12-06

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of Closed Meeting of Art Advisory Panel. SUMMARY: Closed meeting of the Art Advisory Panel will be held in Washington, DC. DATES: The meeting will...

78 FR 59098 - Art Advisory Panel-Notice of Closed Meeting

Science.gov (United States)

2013-09-25

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of closed meeting of Art Advisory Panel. SUMMARY: Closed meeting of the Art Advisory Panel will be held in Washington, DC. DATES: The meeting will...

Biophysics and cancer

CERN Document Server

Nicolini, Claudio

1986-01-01

Since the early times of the Greek philosophers Leucippus and Democritus, and later of the Roman philosopher Lucretius, a simple, fundamental idea emerged that brought the life sciences into the realm of the physical sciences. Atoms, after various interactions, were assumed to acquire stable configurations that corresponded either to the living or to the inanimate world. This simple and unitary theory, which has evolved in successive steps to our present time, remarkably maintained its validity despite several centuries of alternative vicissitudes, and is the foundation of modern biophysics. Some of the recent developments of this ancient idea are the discovery of the direct relationship between spatial structures and chemical activity of such molecules as methane and benzene, and the later discovery of the three-dimensional structure of double-helical DNA, and of its relationship with biological activity. The relationship between the structure of various macromolecules and the function of living cells was on...

Biophysical aspects of using liposomes as delivery vehicles.

Science.gov (United States)

Ulrich, Anne S

2002-04-01

Liposomes are used as biocompatible carriers of drugs, peptides, proteins, plasmic DNA, antisense oligonucleotides or ribozymes, for pharmaceutical, cosmetic, and biochemical purposes. The enormous versatility in particle size and in the physical parameters of the lipids affords an attractive potential for constructing tailor-made vehicles for a wide range of applications. Some of the recent literature will be reviewed here and presented from a biophysical point of view, thus providing a background for the more specialized articles in this special issue on liposome technology. Different properties (size, colloidal behavior, phase transitions, and polymorphism) of diverse lipid formulations (liposomes, lipoplexes, cubic phases, emulsions, and solid lipid nanoparticles) for distinct applications (parenteral, transdermal, pulmonary, and oral administration) will be rationalized in terms of common structural, thermodynamic and kinetic parameters of the lipids. This general biophysical basis helps to understand pharmaceutically relevant aspects such as liposome stability during storage and towards serum, the biodistribution and specific targeting of cargo, and how to trigger drug release and membrane fusion. Methods for the preparation and characterization of liposomal formulations in vitro will be outlined, too.

Proceedings of the international meeting on development, fabrication, and application of Reduced Enrichment fuels for Research and Test Reactors (RERTR). Base technology

Energy Technology Data Exchange (ETDEWEB)

NONE

1983-08-01

The international effort to develop new fuel materials and designs which will make it feasible to fuel research and test reactors throughout the world with low-enrichment uranium, instead of high-enrichment uranium, has made significant progress during the past year. This progress has taken place at research centers located in many different countries, and is of crucial interest to reactor operators and licensors whose geographical distribution is even more varied. It is appropriate, therefore, that international meetings be held periodically to foster direct communication among the specialists in this area. To achieve this purpose, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at the Argonne National Laboratory, sponsored this meeting as the third of a series which begun in 1978. The papers presented at this meeting were divided into sessions according to relevant subject: status of RERTR program and safety issues; development of new fuel types; testing of new fuel elements; specific reactor applications. These proceedings were edited by various members of the RERTR Program.

Proceedings of the international meeting on development, fabrication, and application of Reduced Enrichment fuels for Research and Test Reactors (RERTR). Base technology

International Nuclear Information System (INIS)

1983-08-01

The international effort to develop new fuel materials and designs which will make it feasible to fuel research and test reactors throughout the world with low-enrichment uranium, instead of high-enrichment uranium, has made significant progress during the past year. This progress has taken place at research centers located in many different countries, and is of crucial interest to reactor operators and licensors whose geographical distribution is even more varied. It is appropriate, therefore, that international meetings be held periodically to foster direct communication among the specialists in this area. To achieve this purpose, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at the Argonne National Laboratory, sponsored this meeting as the third of a series which begun in 1978. The papers presented at this meeting were divided into sessions according to relevant subject: status of RERTR program and safety issues; development of new fuel types; testing of new fuel elements; specific reactor applications. These proceedings were edited by various members of the RERTR Program

78 FR 16049 - Art Advisory Panel-Notice of Closed Meeting

Science.gov (United States)

2013-03-13

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of Closed Meeting of Art Advisory Panel. SUMMARY: Closed meeting of the Art Advisory Panel will be held in New York, NY. DATES: The meeting will be...

Epigenetic modulation of the biophysical properties of drug-resistant cell lipids to restore drug transport and endocytic functions.

Science.gov (United States)

Vijayaraghavalu, Sivakumar; Peetla, Chiranjeevi; Lu, Shan; Labhasetwar, Vinod

2012-09-04

In our recent studies exploring the biophysical characteristics of resistant cell lipids, and the role they play in drug transport, we demonstrated the difference of drug-resistant breast cancer cells from drug-sensitive cells in lipid composition and biophysical properties, suggesting that cancer cells acquire a drug-resistant phenotype through the alteration of lipid synthesis to inhibit intracellular drug transport to protect from cytotoxic effect. In cancer cells, epigenetic changes (e.g., DNA hypermethylation) are essential to maintain this drug-resistant phenotype. Thus, altered lipid synthesis may be linked to epigenetic mechanisms of drug resistance. We hypothesize that reversing DNA hypermethylation in resistant cells with an epigenetic drug could alter lipid synthesis, changing the cell membrane's biophysical properties to facilitate drug delivery to overcome drug resistance. Herein we show that treating drug-resistant breast cancer cells (MCF-7/ADR) with the epigenetic drug 5-aza-2'-deoxycytidine (decitabine) significantly alters cell lipid composition and biophysical properties, causing the resistant cells to acquire biophysical characteristics similar to those of sensitive cell (MCF-7) lipids. Following decitabine treatment, resistant cells demonstrated increased sphingomyelinase activity, resulting in a decreased sphingomyelin level that influenced lipid domain structures, increased membrane fluidity, and reduced P-glycoprotein expression. Changes in the biophysical characteristics of resistant cell lipids facilitated doxorubicin transport and restored endocytic function for drug delivery with a lipid-encapsulated form of doxorubicin, enhancing the drug efficacy. In conclusion, we have established a new mechanism for efficacy of an epigenetic drug, mediated through changes in lipid composition and biophysical properties, in reversing cancer drug resistance.

Meeting staff representatives of the European Agencies

CERN Multimedia

Staff Association

2014-01-01

  The AASC (Assembly of Agency Staff Committee) held its 27th Meeting of the specialized European Agencies on 26 and 27 May on the premises of the OHIM (Office for Harmonization in the Internal Market) in Alicante, Spain. Two representatives of the CERN Staff Association, in charge of External Relations, attended as observers. This participation is a useful complement to regular contacts we have with FICSA (Federation of International Civil Servants' Associations), which groups staff associations of the UN Agencies, and the annual CSAIO conferences (Conference of Staff Associations of International Organizations), where each Autumn representatives of international organizations based in Europe meet to discuss themes of common interest to better promote and defend the rights of the international civil servants. All these meetings allow us to remain informed on items that are directly or indirectly related to employment and social conditions of our colleagues in other international and Europ...

Annual public meetings | IDRC - International Development ...

International Development Research Centre (IDRC) Digital Library (Canada)

Inaugural - 2009. Highlight: Getting the Word Out: IDRC's Past, Present, and Future discussed at inaugural public meeting · What we do · Funding · Resources · About IDRC. Knowledge. Innovation. Solutions. Careers · Contact Us · Site map. Sign up now for IDRC news and views sent directly to your inbox each month.

Plasma membrane--cortical cytoskeleton interactions: a cell biology approach with biophysical considerations.

Science.gov (United States)

Kapus, András; Janmey, Paul

2013-07-01

From a biophysical standpoint, the interface between the cell membrane and the cytoskeleton is an intriguing site where a "two-dimensional fluid" interacts with an exceedingly complex three-dimensional protein meshwork. The membrane is a key regulator of the cytoskeleton, which not only provides docking sites for cytoskeletal elements through transmembrane proteins, lipid binding-based, and electrostatic interactions, but also serves as the source of the signaling events and molecules that control cytoskeletal organization and remolding. Conversely, the cytoskeleton is a key determinant of the biophysical and biochemical properties of the membrane, including its shape, tension, movement, composition, as well as the mobility, partitioning, and recycling of its constituents. From a cell biological standpoint, the membrane-cytoskeleton interplay underlies--as a central executor and/or regulator--a multitude of complex processes including chemical and mechanical signal transduction, motility/migration, endo-/exo-/phagocytosis, and other forms of membrane traffic, cell-cell, and cell-matrix adhesion. The aim of this article is to provide an overview of the tight structural and functional coupling between the membrane and the cytoskeleton. As biophysical approaches, both theoretical and experimental, proved to be instrumental for our understanding of the membrane/cytoskeleton interplay, this review will "oscillate" between the cell biological phenomena and the corresponding biophysical principles and considerations. After describing the types of connections between the membrane and the cytoskeleton, we will focus on a few key physical parameters and processes (force generation, curvature, tension, and surface charge) and will discuss how these contribute to a variety of fundamental cell biological functions. © 2013 American Physiological Society.

International Meeting on Languages, Applied Linguistics and Translation

OpenAIRE

Guerra, Luis

2012-01-01

This meeting aims at providing an overview of the current theory and practice, exploring new directions and emerging trends, sharing good practice, and exchanging information regarding foreign languages, applied linguistics and translation. The meeting is an excellent opportunity for the presentation of current or previous language learning and translation projects funded by the European Commission or by other sources. Proposals are invited for one or more of the following topics, in any of t...

Enhancing Irreversible Electroporation by Manipulating Cellular Biophysics with a Molecular Adjuvant.

Science.gov (United States)

Ivey, Jill W; Latouche, Eduardo L; Richards, Megan L; Lesser, Glenn J; Debinski, Waldemar; Davalos, Rafael V; Verbridge, Scott S

2017-07-25

Pulsed electric fields applied to cells have been used as an invaluable research tool to enhance delivery of genes or other intracellular cargo, as well as for tumor treatment via electrochemotherapy or tissue ablation. These processes involve the buildup of charge across the cell membrane, with subsequent alteration of transmembrane potential that is a function of cell biophysics and geometry. For traditional electroporation parameters, larger cells experience a greater degree of membrane potential alteration. However, we have recently demonstrated that the nuclear/cytoplasm ratio (NCR), rather than cell size, is a key predictor of response for cells treated with high-frequency irreversible electroporation (IRE). In this study, we leverage a targeted molecular therapy, ephrinA1, known to markedly collapse the cytoplasm of cells expressing the EphA2 receptor, to investigate how biophysical cellular changes resulting from NCR manipulation affect the response to IRE at varying frequencies. We present evidence that the increase in the NCR mitigates the cell death response to conventional electroporation pulsed-electric fields (∼100 μs), consistent with the previously noted size dependence. However, this same molecular treatment enhanced the cell death response to high-frequency electric fields (∼1 μs). This finding demonstrates the importance of considering cellular biophysics and frequency-dependent effects in developing electroporation protocols, and our approach provides, to our knowledge, a novel and direct experimental methodology to quantify the relationship between cell morphology, pulse frequency, and electroporation response. Finally, this novel, to our knowledge, combinatorial approach may provide a paradigm to enhance in vivo tumor ablation through a molecular manipulation of cellular morphology before IRE application. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

A biotic video game smart phone kit for formal and informal biophysics education

Science.gov (United States)

Kim, Honesty; Lee, Seung Ah; Riedel-Kruse, Ingmar

2015-03-01

Novel ways for formal and informal biophysics education are important. We present a low-cost biotic game design kit that incorporates microbial organisms into an interactive gaming experience: A 3D-printable microscope containing four LEDs controlled by a joystick enable human players to provide directional light stimuli to the motile single-celled organism Euglena gracilis. These cellular behaviors are displayed on the integrated smart phone. Real time cell-tracking couples these cells into interactive biotic video game play, i.e., the human player steers Euglena to play soccer with virtual balls and goals. The player's learning curve in mastering this fun game is intrinsically coupled to develop a deeper knowledge about Euglena's cell morphology and the biophysics of its phototactic behavior. This kit is dual educational - via construction and via play - and it provides an engaging theme for a formal biophysics devices class as well as to be presented in informal outreach activities; its low cost and open soft- and hardware should enable wide adoption.

Biophysical and lipofection studies of DOTAP analogs.

Science.gov (United States)

Regelin, A E; Fankhaenel, S; Gürtesch, L; Prinz, C; von Kiedrowski, G; Massing, U

2000-03-15

In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles) membrane fluidity of liposomes and lipoplexes were determined, and lipofection efficiency was tested in a luciferase reporter gene assay. DOTAP analogs were used as single components or combined with a helper lipid, either DOPE or cholesterol. Stability of liposomes was a precondition for formation of temporarily stable lipoplexes. Addition of DOPE or cholesterol improved liposome and lipoplex stability. Transfection efficiencies of lipoplexes based on pure DOTAP analogs could be correlated with stability data and membrane fluidity at transfection temperature. Inclusion of DOPE led to rather uniform transfection and anisotropy profiles, corresponding to lipoplex stability. Cholesterol-containing lipoplexes were generally stable, showing high transfection efficiency at low relative fluidity. Our results demonstrate that the efficiency of gene transfer mediated by monocationic lipids is greatly influenced by lipoplex biophysics due to lipid composition. The measurement of fluorescence anisotropy is an appropriate method to characterize membrane fluidity within a defined system of liposomes or lipoplexes and may be helpful to elucidate structure-activity relationships.

78 FR 54925 - Audit Committee Meeting of The Board of Directors; Sunshine Act Meeting

Science.gov (United States)

2013-09-06

... NEIGHBORHOOD REINVESTMENT CORPORATION Audit Committee Meeting of The Board of Directors; Sunshine.... Executive Session With Internal Audit Director III. Title Change of the Internal Audit Director IV. Executive Session With Officers: Pending Litigation V. FY14 Risk Assessment & Internal Audit Plan VI...

Biophysical approach to low back pain: a pilot report.

Science.gov (United States)

Foletti, Alberto; Pokorný, Jiry

2015-01-01

Since biophysical treatment has been reported to be effective in the general management of pain, we decided to assess the specific effect and treatment duration of this therapeutic strategy in low back pain. We were interested in verifying the possibility that a single clinical procedure could reduce pain and improve patients' quality of life within a period of three months. An Electromagnetic Information Transfer Through Aqueous System was employed to record endogenous therapeutic signals from each individual using an electromagnetic recording device (Med Select 729). A highly significant reduction in the Roland Morris low back pain and disability questionnaire score was observed after 3 months following a single biophysical intervention (11.83 ± 6 at baseline versus 2.3 ± 3.25 at 3 months, p < 0.0001). This preliminary report provides further evidence of the theoretical implications and clinical applications of Quantum Electro Dynamic concepts in biology and medicine.

Quantum-Sequencing: Biophysics of quantum tunneling through nucleic acids

Science.gov (United States)

Casamada Ribot, Josep; Chatterjee, Anushree; Nagpal, Prashant

2014-03-01

Tunneling microscopy and spectroscopy has extensively been used in physical surface sciences to study quantum tunneling to measure electronic local density of states of nanomaterials and to characterize adsorbed species. Quantum-Sequencing (Q-Seq) is a new method based on tunneling microscopy for electronic sequencing of single molecule of nucleic acids. A major goal of third-generation sequencing technologies is to develop a fast, reliable, enzyme-free single-molecule sequencing method. Here, we present the unique ``electronic fingerprints'' for all nucleotides on DNA and RNA using Q-Seq along their intrinsic biophysical parameters. We have analyzed tunneling spectra for the nucleotides at different pH conditions and analyzed the HOMO, LUMO and energy gap for all of them. In addition we show a number of biophysical parameters to further characterize all nucleobases (electron and hole transition voltage and energy barriers). These results highlight the robustness of Q-Seq as a technique for next-generation sequencing.

When managerialism meets internationalism

DEFF Research Database (Denmark)

Dykmann, Klaas; Lewis, Jenny; Bentzen, Sune Raahede

2014-01-01

This article examines whether reform ideas that gained influence in national-level bureaucracies in the 1970s were also on the United Nations’ internal agenda. The Joint Inspection Unit (Bertrand) Report of 1971 is the focus of this analysis, as it addressed personnel problems in the UN Secretari...

A note on the roles of quantum and mechanical models in social biophysics.

Science.gov (United States)

Takahashi, Taiki; Kim, Song-Ju; Naruse, Makoto

2017-11-01

Recent advances in the applications of quantum models into various disciplines such as cognitive science, social sciences, economics, and biology witnessed enormous achievements and possible future progress. In this paper, we propose one of the most promising directions in the applications of quantum models: the combination of quantum and mechanical models in social biophysics. The possible resulting discipline may be called as experimental quantum social biophysics and could foster our understandings of the relationships between the society and individuals. Copyright © 2017 Elsevier Ltd. All rights reserved.

Biophysical processes in the Indian Ocean

Digital Repository Service at National Institute of Oceanography (India)

Mc; Murtugudde, R.; Vialard, J.; Vinayachandran, P.N.; Wiggert, J.D.; Hood, R.R.; Shankar, D.; Shetye, S.R.

Ocean Biogeochemical Processes and Ecological Variability Geophysical Monograph Series 185 Copyright 200� by the American Geophysical Union. 10.102�/2008GM000768 Biophysical Processes in the Indian Ocean J. P. McCreary, 1 R. Murtugudde, 2 J. Vialard, 3...) also plots the upper-layer thickness, h 1 , from the model of McCreary et al. [1��3] (hereinafter referred to as MKM); h 1 simulates the structure of the top of the actual thermocline reasonably well, except that it is somewhat too thin from 5...

22 CFR 401.5 - Meetings.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Meetings. 401.5 Section 401.5 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.5 Meetings. (a... meeting shall be open to the public, it shall give such advance notice to this effect as it considers...

Hierarchy and Interactions in Environmental Interfaces Regarded as Biophysical Complex Systems

Science.gov (United States)

Mihailovic, Dragutin T.; Balaz, Igor

The field of environmental sciences is abundant with various interfaces and is the right place for the application of new fundamental approaches leading towards a better understanding of environmental phenomena. For example, following the definition of environmental interface by Mihailovic and Balaž [23], such interface can be placed between: human or animal bodies and surrounding air, aquatic species and water and air around them, and natural or artificially built surfaces (vegetation, ice, snow, barren soil, water, urban communities) and the atmosphere. Complex environmental interface systems are open and hierarchically organised, interactions between their constituent parts are nonlinear, and the interaction with the surrounding environment is noisy. These systems are therefore very sensitive to initial conditions, deterministic external perturbations and random fluctuations always present in nature. The study of noisy non-equilibrium processes is fundamental for modelling the dynamics of environmental interface systems and for understanding the mechanisms of spatio-temporal pattern formation in contemporary environmental sciences, particularly in environmental fluid mechanics. In modelling complex biophysical systems one of the main tasks is to successfully create an operative interface with the external environment. It should provide a robust and prompt translation of the vast diversity of external physical and/or chemical changes into a set of signals, which are "understandable" for an organism. Although the establishment of organisation in any system is of crucial importance for its functioning, it should not be forgotten that in biophysical systems we deal with real-life problems where a number of other conditions should be reached in order to put the system to work. One of them is the proper supply of the system by the energy. Therefore, we will investigate an aspect of dynamics of energy flow based on the energy balance equation. The energy as well as

Linking biophysical models and public preferences for ecosystem service assessments: a case study for the Southern Rocky Mountains

Science.gov (United States)

Bagstad, Kenneth J.; Reed, James; Semmens, Darius J.; Sherrouse, Ben C.; Troy, Austin

2016-01-01

Through extensive research, ecosystem services have been mapped using both survey-based and biophysical approaches, but comparative mapping of public values and those quantified using models has been lacking. In this paper, we mapped hot and cold spots for perceived and modeled ecosystem services by synthesizing results from a social-values mapping study of residents living near the Pike–San Isabel National Forest (PSI), located in the Southern Rocky Mountains, with corresponding biophysically modeled ecosystem services. Social-value maps for the PSI were developed using the Social Values for Ecosystem Services tool, providing statistically modeled continuous value surfaces for 12 value types, including aesthetic, biodiversity, and life-sustaining values. Biophysically modeled maps of carbon sequestration and storage, scenic viewsheds, sediment regulation, and water yield were generated using the Artificial Intelligence for Ecosystem Services tool. Hotspots for both perceived and modeled services were disproportionately located within the PSI’s wilderness areas. Additionally, we used regression analysis to evaluate spatial relationships between perceived biodiversity and cultural ecosystem services and corresponding biophysical model outputs. Our goal was to determine whether publicly valued locations for aesthetic, biodiversity, and life-sustaining values relate meaningfully to results from corresponding biophysical ecosystem service models. We found weak relationships between perceived and biophysically modeled services, indicating that public perception of ecosystem service provisioning regions is limited. We believe that biophysical and social approaches to ecosystem service mapping can serve as methodological complements that can advance ecosystem services-based resource management, benefitting resource managers by showing potential locations of synergy or conflict between areas supplying ecosystem services and those valued by the public.

Effects of LiDAR point density, sampling size and height threshold on estimation accuracy of crop biophysical parameters.

Science.gov (United States)

Luo, Shezhou; Chen, Jing M; Wang, Cheng; Xi, Xiaohuan; Zeng, Hongcheng; Peng, Dailiang; Li, Dong

2016-05-30

Vegetation leaf area index (LAI), height, and aboveground biomass are key biophysical parameters. Corn is an important and globally distributed crop, and reliable estimations of these parameters are essential for corn yield forecasting, health monitoring and ecosystem modeling. Light Detection and Ranging (LiDAR) is considered an effective technology for estimating vegetation biophysical parameters. However, the estimation accuracies of these parameters are affected by multiple factors. In this study, we first estimated corn LAI, height and biomass (R2 = 0.80, 0.874 and 0.838, respectively) using the original LiDAR data (7.32 points/m2), and the results showed that LiDAR data could accurately estimate these biophysical parameters. Second, comprehensive research was conducted on the effects of LiDAR point density, sampling size and height threshold on the estimation accuracy of LAI, height and biomass. Our findings indicated that LiDAR point density had an important effect on the estimation accuracy for vegetation biophysical parameters, however, high point density did not always produce highly accurate estimates, and reduced point density could deliver reasonable estimation results. Furthermore, the results showed that sampling size and height threshold were additional key factors that affect the estimation accuracy of biophysical parameters. Therefore, the optimal sampling size and the height threshold should be determined to improve the estimation accuracy of biophysical parameters. Our results also implied that a higher LiDAR point density, larger sampling size and height threshold were required to obtain accurate corn LAI estimation when compared with height and biomass estimations. In general, our results provide valuable guidance for LiDAR data acquisition and estimation of vegetation biophysical parameters using LiDAR data.

Modelling benthic biophysical drivers of ecosystem structure and biogeochemical response

Science.gov (United States)

Stephens, Nicholas; Bruggeman, Jorn; Lessin, Gennadi; Allen, Icarus

2016-04-01

The fate of carbon deposited at the sea floor is ultimately decided by biophysical drivers that control the efficiency of remineralisation and timescale of carbon burial in sediments. Specifically, these drivers include bioturbation through ingestion and movement, burrow-flushing and sediment reworking, which enhance vertical particulate transport and solute diffusion. Unfortunately, these processes are rarely satisfactorily resolved in models. To address this, a benthic model that explicitly describes the vertical position of biology (e.g., habitats) and biogeochemical processes is presented that includes biological functionality and biogeochemical response capturing changes in ecosystem structure, benthic-pelagic fluxes and biodiversity on inter-annual timescales. This is demonstrated by the model's ability to reproduce temporal variability in benthic infauna, vertical pore water nutrients and pelagic-benthic solute fluxes compared to in-situ data. A key advance is the replacement of bulk parameterisation of bioturbation by explicit description of the bio-physical processes responsible. This permits direct comparison with observations and determination of key parameters in experiments. Crucially, the model resolves the two-way interaction between sediment biogeochemistry and ecology, allowing exploration of the benthic response to changing environmental conditions, the importance of infaunal functional traits in shaping benthic ecological structure and the feedback the resulting bio-physical processes exert on pore water nutrient profiles. The model is actively being used to understand shelf sea carbon cycling, the response of the benthos to climatic change, food provision and other societal benefits.

Developing a protocol for managing the biophysical condition of a ...

African Journals Online (AJOL)

Their function will focus on the overall management of water resources on a ... for the integrated management of the biophysical component of a catchment, with ... and implement a protocol which will combine and integrate the knowledge of ...

IGORR 2: Proceedings of the 2. meeting of the International Group On Research Reactors

Energy Technology Data Exchange (ETDEWEB)

NONE

1992-07-01

The International group on Research Reactors was formed to facilitate the sharing of knowledge and experience among those institutions and individuals who are actively working to design, build, and promote new research reactors or to make significant upgrades to existing facilities. Sessions during this second meeting were devoted to research reactor reports (GRENOBLE reactor, FRM-II, HIFAR, PIK, reactors at JAERI, MAPLE, ANS, NIST, MURR, TRIGA, BR-2, SIRIUS 2); other neutron sources; and two workshops were dealing with research and development results and needs and reports on progress in needed of R and D areas identified at IGORR 1.

IGORR 2: Proceedings of the 2. meeting of the International Group On Research Reactors

International Nuclear Information System (INIS)

1992-01-01

The International group on Research Reactors was formed to facilitate the sharing of knowledge and experience among those institutions and individuals who are actively working to design, build, and promote new research reactors or to make significant upgrades to existing facilities. Sessions during this second meeting were devoted to research reactor reports (GRENOBLE reactor, FRM-II, HIFAR, PIK, reactors at JAERI, MAPLE, ANS, NIST, MURR, TRIGA, BR-2, SIRIUS 2); other neutron sources; and two workshops were dealing with research and development results and needs and reports on progress in needed of R and D areas identified at IGORR 1

Proceedings of the international specialist meeting on BWR-pressure suppression containment technology. Vol. 1

International Nuclear Information System (INIS)

Schultheiss, G.F.

1981-01-01

In the frame of R + D-work for BWR-pressure suppression systems the GKSS-Forschungszentrum Geesthacht GmbH organized an international specialist meeting. All important safety relevant aspects of pressure suppression system technology have been included. About 60 experts from USA, Japan, Sweden, Italy, Netherlands and the Federal Republic of Germany participated. They came from licensing authorities, vendors, research centers and universities. In 24 papers they have shown the world-wide present status of theoretical and experimental know-how on pressure suppression system behaviour. In discussions and working groups recommendations for future work have been compiled. (orig.) [de

Proceedings of the international specialist meeting on BWR-pressure suppression containment technology. Vol. 2

International Nuclear Information System (INIS)

Schultheiss, G.F.

1981-01-01

In the frame of R + D-work for BWR-pressure suppression systems the GKSS-Forschungszentrum Geesthacht GmbH organized an international specialist meeting. All important safety relevant aspects of pressure suppression system technology have been included. About 60 experts from USA, Japan, Sweden, Italy, Netherland and the Federal Republic of Germany participated. They came from licensing authorities, vendors, research centers and universities. In 24 papers they have shown the world-wide present status of theoretical and experimental know-how on pressure suppression system behaviour. In discussions and working groups recommendations for future work have been compiled. (orig.) [de

Advances in fast reactor technology. Proceedings of the 30. meeting of the International Working Group on Fast Reactors

International Nuclear Information System (INIS)

1998-04-01

Individual States were largely responsible for early developments in experimental and prototype liquid metal fast reactors (LMFRs). However, for development of advanced LMFRs, international co-operation plays an important role. The IAEA seeks to promote such co-operation. For R and D incorporating innovative features, international co-operation allows pooling of resources and expertise in areas of common interest. Information on experience gained from R and D, and from the operation and construction of fast reactors, has been reviewed periodically by the International Working Group on Fast Reactors (IWGFR). These proceedings contain updated a new information on the status of LMFR development, as reported at the 30th meeting of the IWGFR, held in Beijing, China, from 13 to 16 May 1997

Advances in fast reactor technology. Proceedings of the 30. meeting of the International Working Group on Fast Reactors

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-04-01

Individual States were largely responsible for early developments in experimental and prototype liquid metal fast reactors (LMFRs). However, for development of advanced LMFRs, international co-operation plays an important role. The IAEA seeks to promote such co-operation. For R and D incorporating innovative features, international co-operation allows pooling of resources and expertise in areas of common interest. Information on experience gained from R and D, and from the operation and construction of fast reactors, has been reviewed periodically by the International Working Group on Fast Reactors (IWGFR). These proceedings contain updated a new information on the status of LMFR development, as reported at the 30th meeting of the IWGFR, held in Beijing, China, from 13 to 16 May 1997. Refs,figs,tabs.

Proceedings of the international information exchange meeting on diffusion phenomena in bentonite and rock. Aiming at the safety assessment of the geological disposal

International Nuclear Information System (INIS)

Sato, Haruo; Hatanaka, Koichiro

2009-12-01

The international information exchange meeting on diffusion phenomena in bentonite and rock was held at Horonobe Underground Research Center on 18th July, 2006. This meeting was hosted by Japan Atomic Energy Agency (JAEA) and supported by Hokkaido University and Radioactive Waste Management Funding and Research Center (RWMC). Totally 18 scientists who are specialists of diffusion participated from Finland (VTT) and Japan (7 research organizations) in the meeting. 6 presentations were made on recent research activities and outputs on diffusion phenomena in bentonite and rock. The 6 papers are indexed individually. (J.P.N.)

Safety culture in nuclear installations: Summary of an international topical meeting

International Nuclear Information System (INIS)

Carnino, A.; Derrough, M.; Weimann, G.

1996-01-01

An international topical meeting, Safety Culture in Nuclear Installations, was organized by the American Nuclear Society (ANS) Austria Local Section, cosponsored by the ANS Nuclear Reactor Safety and Human Factors Divisions in cooperation with the Nuclear Energy Agency of the Organization for Economic Cooperation and Development (NEA/OECD) and held in Vienna April 24-28, 1995. Some 250 experts from 30 different countries and organizations took part in the 85 paper presentations and two workshops. The concept of safety culture was initially used in the first International Nuclear Safety Advisory Group (INSAG) report on the Chernobyl accident analysis report in 1986. Although some elements of safety culture have been used over the years in nuclear safety activities, the new phrase safety culture and the concept were found interesting as highlighting the 'soft' aspects of safety and as encompassing more than human errors. Unfortunately, for many years it was used more in the way of identifying lack of safety culture. Conscious of this application, INSAG further developed the safety culture concept in the INSAG 4 report: The report contains a definition, the universal aspects of safety culture, the two main components of safety culture management and individual behaviour, and performance indicators of a good safety culture. This report is now quite famous and adopted with some additions or complementary definitions by many institutes and organizations for their daily activities

Biophysical properties of the normal-sized aorta in patients with Marfan syndrome: evaluation with MR flow mapping

NARCIS (Netherlands)

Groenink, M.; de Roos, A.; Mulder, B. J.; Verbeeten, B.; Timmermans, J.; Zwinderman, A. H.; Spaan, J. A.; van der Wall, E. E.

2001-01-01

PURPOSE: To investigate the feasibility of magnetic resonance (MR) flow mapping in the assessment of aortic biophysical properties in patients with Marfan syndrome and to detect differences in biophysical properties in the normal-sized aorta distal to the aortic root between these patients and

International Atomic Energy Agency specialists meeting on experience in ageing, maintenance, and modernization of instrumentation and control systems for improving nuclear power plant availability

Energy Technology Data Exchange (ETDEWEB)

1993-10-01

This report presents the proceedings of the Specialist`s Meeting on Experience in Aging, Maintenance and Modernization of Instrumentation and Control Systems for Improving Nuclear Power Plant Availability that was held at the Ramada Inn in Rockville, Maryland on May 5--7, 1993. The Meeting was presented in cooperation with the Electric Power Research Institute, Oak Ridge National Laboratory and the International Atomic Energy Agency. There were approximately 65 participants from 13 countries at the Meeting. Individual reports have been cataloged separately.

International Atomic Energy Agency specialists meeting on experience in ageing, maintenance, and modernization of instrumentation and control systems for improving nuclear power plant availability

International Nuclear Information System (INIS)

1993-10-01

This report presents the proceedings of the Specialist's Meeting on Experience in Aging, Maintenance and Modernization of Instrumentation and Control Systems for Improving Nuclear Power Plant Availability that was held at the Ramada Inn in Rockville, Maryland on May 5--7, 1993. The Meeting was presented in cooperation with the Electric Power Research Institute, Oak Ridge National Laboratory and the International Atomic Energy Agency. There were approximately 65 participants from 13 countries at the Meeting. Individual reports have been cataloged separately

A Method Sustaining the Bioelectric, Biophysical, and Bioenergetic Function of Cultured Rabbit Atrial Cells

OpenAIRE

Noa Kirschner Peretz; Sofia Segal; Limor Arbel-Ganon; Ronen Ben Jehuda; Ronen Ben Jehuda; Yuval Shemer; Yuval Shemer; Binyamin Eisen; Binyamin Eisen; Moran Davoodi; Ofer Binah; Ofer Binah; Yael Yaniv

2017-01-01

Culturing atrial cells leads to a loss in their ability to be externally paced at physiological rates and to maintain their shape. We aim to develop a culture method that sustains the shape of atrial cells along with their biophysical and bioenergetic properties in response to physiological pacing. We hypothesize that adding 2,3-Butanedione 2-monoxime (BDM), which inhibits contraction during the culture period, will preserve these biophysical and bioenergetic properties. Rabbit atrial cells w...

Nanoscale biophysics of the cell

CERN Document Server

Ashrafuzzaman, Mohammad

2018-01-01

Macroscopic cellular structures and functions are generally investigated using biological and biochemical approaches. But these methods are no longer adequate when one needs to penetrate deep into the small-scale structures and understand their functions. The cell is found to hold various physical structures, molecular machines, and processes that require physical and mathematical approaches to understand and indeed manipulate them. Disorders in general cellular compartments, perturbations in single molecular structures, drug distribution therein, and target specific drug-binding, etc. are mostly physical phenomena. This book will show how biophysics has revolutionized our way of addressing the science and technology of nanoscale structures of cells, and also describes the potential for manipulating the events that occur in them.

Workshops of the Fifth International Brain-Computer Interface Meeting: Defining the Future.

Science.gov (United States)

Huggins, Jane E; Guger, Christoph; Allison, Brendan; Anderson, Charles W; Batista, Aaron; Brouwer, Anne-Marie A-M; Brunner, Clemens; Chavarriaga, Ricardo; Fried-Oken, Melanie; Gunduz, Aysegul; Gupta, Disha; Kübler, Andrea; Leeb, Robert; Lotte, Fabien; Miller, Lee E; Müller-Putz, Gernot; Rutkowski, Tomasz; Tangermann, Michael; Thompson, David Edward

2014-01-01

The Fifth International Brain-Computer Interface (BCI) Meeting met June 3-7 th , 2013 at the Asilomar Conference Grounds, Pacific Grove, California. The conference included 19 workshops covering topics in brain-computer interface and brain-machine interface research. Topics included translation of BCIs into clinical use, standardization and certification, types of brain activity to use for BCI, recording methods, the effects of plasticity, special interest topics in BCIs applications, and future BCI directions. BCI research is well established and transitioning to practical use to benefit people with physical impairments. At the same time, new applications are being explored, both for people with physical impairments and beyond. Here we provide summaries of each workshop, illustrating the breadth and depth of BCI research and high-lighting important issues for future research and development.

Selected Peer-Reviewed Articles from The International Meeting on Developments in Materials, Processes and Applications of Nanotechnology (MPA 2008), UK

NARCIS (Netherlands)

Ali, Nasar; De Hosson, Jeff. Th. M.; Ahmed, W.

The International Meeting on Developments in Materials, Processes and Applications of Nanotechnology (MPA 2008) held at Robinson College, University of Cambridge, UK was the second event of the MPA conference series. The first MPA-2007, held at the University of Ulster, UK officially launched the

Third International E. coli genome meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

1994-12-31

Proceedings of the Third E. Coli Genome Meeting are provided. Presentations were divided into sessions entitled (1) Large Scale Sequencing, Sequence Analysis; (2) Databases; (3) Sequence Analysis; (4) Sequence Divergence in E. coli Strains; (5) Repeated Sequences and Regulatory Motifs; (6) Mutations, Rearrangements and Stress Responses; and (7) Origins of New Genes. The document provides a collection of abstracts of oral and poster presentations.

Epiphanies, velcro balls and McDonaldization: highlights from the 5th Meeting of the International Society for Behavioral Nutrition and Physical Activity

Directory of Open Access Journals (Sweden)

Ball Kylie

2006-09-01

Full Text Available Abstract This commentary provides an overview and selected highlights from the scientific program of the 5th Annual Meeting of the International Society for Behavioral Nutrition and Physical Activity.

Coupling Biophysical and Socioeconomic Models for Coral Reef Systems in Quintana Roo, Mexican Caribbean

Directory of Open Access Journals (Sweden)

Jessica Melbourne-Thomas

2011-09-01

Full Text Available Transdisciplinary approaches that consider both socioeconomic and biophysical processes are central to understanding and managing rapid change in coral reef systems worldwide. To date, there have been limited attempts to couple the two sets of processes in dynamic models for coral reefs, and these attempts are confined to reef systems in developed countries. We present an approach to coupling existing biophysical and socioeconomic models for coral reef systems in the Mexican state of Quintana Roo. The biophysical model is multiscale, using dynamic equations to capture local-scale ecological processes on individual reefs, with reefs connected at regional scales by the ocean transport of larval propagules. The agent-based socioeconomic model simulates changes in tourism, fisheries, and urbanization in the Quintana Roo region. Despite differences in the formulation and currencies of the two models, we were able to successfully modify and integrate them to synchronize and define information flows and feedbacks between them. A preliminary evaluation of the coupled model system indicates that the model gives reasonable predictions for fisheries and ecological variables and can be used to examine scenarios for future social-ecological change in Quintana Roo. We provide recommendations for where efforts might usefully be focused in future attempts to integrate models of biophysical and socioeconomic processes, based on the limitations of our coupled system.

Winnowing and Flocculation in Bio-physical Cohesive Substrate: A Flume Experimental and Estuarine Study

Science.gov (United States)

Ye, L.; Parsons, D. R.; Manning, A. J.

2016-12-01

Cohesive sediment, or mud, is ubiquitously found in most aqueous environments, such as coasts and estuaries. The study of cohesive sediment behaviors requires the synchronous description of mutual interactions of grains (e.g., winnowing and flocculation), their physical properties (e.g., grain size) and also the ambient water. Herein, a series of flume experiments (14 runs) with different substrate mixtures of sand-clay-EPS (Extracellular Polymeric Substrates: secreted by aquatic microorganisms) are combined with an estuarine field survey (Dee estuary, NW England) to investigate the behavior of suspensions over bio-physical cohesive substrates. The experimental results indicate that winnowing and flocculation occur pervasively in bio-physical cohesive flow systems. Importantly however, the evolution of the bed and bedform dynamics and hence turbulence production can be lower when cohesivity is high. The estuarine survey also revealed that the bio-physical cohesion provided by both the clay and microorganism fractions in the bed, that pervasively exists in many natural estuarine systems, plays a significant role in controlling the interactions between bed substrate and sediment suspension and deposition, including controlling processes such as sediment winnowing, flocculation and re-deposition. Full understanding of these processes are essential in advancing sediment transport modelling and prediction studies across natural estuarine systems and the work will report on an improved conceptual model for sediment sorting deposition in bio-physical cohesive substrates.

ICANS-XIV. The fourteenth meeting of the international collaboration on advanced neutron sources

International Nuclear Information System (INIS)

Carpenter, J. M.; Tobin, C. A.

1999-01-01

The meeting began with a reception on Sunday evening. Monday's plenary sessions included status reports on the four operating spallation neutron sources, IPNS, ISIS, KENS, and the Lujan Center; on the INR source under construction at Troitsk; on the IBR-2 pulsed reactor at Dubna; and on proposals for five new installations. We also heard reports on spin-off activities: the ASTE tests (liquid mercury target tests at the AGS accelerator at Brookhaven), the ACoM activities (developments aimed to provide cold moderators suitable for high-power pulsed sources), and the International Workshop on Cold Moderators for Pulsed Neutron Sources, held in September 1997 at Argonne. Jose Alonso and Bob Macek delivered enlightening invited talks overviewing linear accelerators and rings for spallation neutron sources. The rest of the meeting was devoted to targets and moderators and to instrumentation in a normal rotation of ICANS topics. There were altogether 84 oral reports and 23 poster presentations. On Tuesday and on Wednesday morning, we divided into separate series of sessions on Instrumentation and on Targets and Moderators. In the first, we had reports and discussions on instrumentation and techniques, on computer software, on instrument suites, and on new instruments and equipment. In the second series were sessions on liquid target systems, on solid target systems, on neutron production and target physics, on moderator physics and performance, and on target and moderator neutronics. The Tuesday evening meetings went on until 10:00, making for a 14-hour working day. That everyone willingly endured the long hours is a credit to the dedication of the attendees. On Wednesday afternoon, we boarded buses for the 1-hour trip to Argonne, where attendees toured IPNS and the Advanced Photon Source. Returning to Starved Rock, we enjoyed boat rides on the Illinois River and then a barbecue banquet dinner at the Lodge. All day Thursday and Friday morning, the attendees, in small

76 FR 53169 - Art Advisory Panel-Notice of Closed Meeting

Science.gov (United States)

2011-08-25

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of closed meeting of Art Advisory Panel for Fine Art. SUMMARY: Closed meeting of the Art Advisory Panel will be held in Washington, DC. DATES: The...

75 FR 54444 - Art Advisory Panel-Notice of Closed Meeting

Science.gov (United States)

2010-09-07

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of Closed Meeting of Art Advisory Panel for Fine Art. SUMMARY: Closed meeting of the Art Advisory Panel will be held in Washington, DC. DATES: The...

76 FR 17189 - Art Advisory Panel-Notice of closed meeting

Science.gov (United States)

2011-03-28

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of closed meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of closed meeting of Art Advisory Panel for Fine Art. SUMMARY: Closed meeting of the Art Advisory Panel will be held in Washington, DC. DATES: The...

IFPA meeting 2009 workshops report

DEFF Research Database (Denmark)

Lash, G.E.; Burton, G.J.; Chamley, L.W.

2010-01-01

Workshops are an important part of the annual meeting of the International Federation of Placenta Associations (IFPA). At IFPA Meeting 2009 diverse topics were discussed in twelve themed workshops. Topics covered included: immune response to pregnancy; signaling between fetus and placenta...

Meetings all over the world: structural and psychological characteristics of meetings in different countries

NARCIS (Netherlands)

van Eerde, W.; Buengeler, C.; Allen, J.A.; Lehmann-Willenbrock, N.; Rogelberg, S.G.

2015-01-01

Previous research on work meetings has mainly been conducted in the Anglo-Saxon context. In this chapter, we add an international perspective that addresses this question: Does the national context of the meeting influence how it is structured and perceived? We provide a descriptive-comparative

Anti-pulmonary fibrotic activity of salvianolic acid B was screened by a novel method based on the cyto-biophysical properties

International Nuclear Information System (INIS)

Liu, Miao; Zheng, Mingjing; Xu, Hanying; Liu, Lianqing; Li, Yanchun; Xiao, Wei; Li, Jianchun; Ma, Enlong

2015-01-01

Various methods have been used to evaluate anti-fibrotic activity of drugs. However, most of them are complicated, labor-intensive and lack of efficiency. This study was intended to develop a rapid method for anti-fibrotic drugs screening based on biophysical properties. A549 cells in vitro were stimulated with transforming growth factor-β1 (TGF-β1), and fibrogenesis was confirmed by conventional immunological assays. Meanwhile, the alterations of cyto-biophysical properties including morphology, roughness and stiffness were measured utilizing atomic force microscopy (AFM). It was found that fibrogenesis was accompanied with changes of cellular biophysical properties. TGF-β1-stimulated A549 cells became remarkably longer, rougher and stiffer than the control. Then, the effect of N-acetyl-L-cysteine (NAC) as a positive drug on ameliorating fibrogenesis in TGF-β1-stimulated A549 cells was verified respectively by immunological and biophysical markers. The result of Principal Component Analysis showed that stiffness was a leading index among all biophysical markers during fibrogenesis. Salvianolic acid B (SalB), a natural anti-oxidant, was detected by AFM to protect TGF-β1-stimulated A549 cells against stiffening. Then, SalB treatment was provided in preventive mode on a rat model of bleomycin (BLM) -induced pulmonary fibrosis. The results showed that SalB treatment significantly ameliorated BLM-induced histological alterations, blocked collagen accumulations and reduced α-SMA expression in lung tissues. All these results revealed the anti-pulmonary fibrotic activity of SalB. Detection of cyto-biophysical properties were therefore recommended as a rapid method for anti-pulmonary fibrotic drugs screening. - Highlights: • Fibrogenesis was accompanied with the changes of cyto-biophysical properties. • Cyto-biophysical properties could be markers for anti-fibrotic drugs screening. • Stiffness is a leading index among all biophysical markers. • SalB was

Anti-pulmonary fibrotic activity of salvianolic acid B was screened by a novel method based on the cyto-biophysical properties

Energy Technology Data Exchange (ETDEWEB)

Liu, Miao; Zheng, Mingjing; Xu, Hanying [Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110016 (China); Liu, Lianqing [Shenyang Institute of Automation China Academy of Sciences, Shenyang, 110016 (China); Li, Yanchun [Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110016 (China); Xiao, Wei [Jiangsu Kanion Pharmaceutical Co., Ltd., Nanjing, 222001 (China); Li, Jianchun, E-mail: lijianchun0317@sina.com.cn [Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110016 (China); Ma, Enlong, E-mail: enlong_ma2014@hotmail.com [Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110016 (China); Jiangsu Kanion Pharmaceutical Co., Ltd., Nanjing, 222001 (China)

2015-12-04

Various methods have been used to evaluate anti-fibrotic activity of drugs. However, most of them are complicated, labor-intensive and lack of efficiency. This study was intended to develop a rapid method for anti-fibrotic drugs screening based on biophysical properties. A549 cells in vitro were stimulated with transforming growth factor-β1 (TGF-β1), and fibrogenesis was confirmed by conventional immunological assays. Meanwhile, the alterations of cyto-biophysical properties including morphology, roughness and stiffness were measured utilizing atomic force microscopy (AFM). It was found that fibrogenesis was accompanied with changes of cellular biophysical properties. TGF-β1-stimulated A549 cells became remarkably longer, rougher and stiffer than the control. Then, the effect of N-acetyl-L-cysteine (NAC) as a positive drug on ameliorating fibrogenesis in TGF-β1-stimulated A549 cells was verified respectively by immunological and biophysical markers. The result of Principal Component Analysis showed that stiffness was a leading index among all biophysical markers during fibrogenesis. Salvianolic acid B (SalB), a natural anti-oxidant, was detected by AFM to protect TGF-β1-stimulated A549 cells against stiffening. Then, SalB treatment was provided in preventive mode on a rat model of bleomycin (BLM) -induced pulmonary fibrosis. The results showed that SalB treatment significantly ameliorated BLM-induced histological alterations, blocked collagen accumulations and reduced α-SMA expression in lung tissues. All these results revealed the anti-pulmonary fibrotic activity of SalB. Detection of cyto-biophysical properties were therefore recommended as a rapid method for anti-pulmonary fibrotic drugs screening. - Highlights: • Fibrogenesis was accompanied with the changes of cyto-biophysical properties. • Cyto-biophysical properties could be markers for anti-fibrotic drugs screening. • Stiffness is a leading index among all biophysical markers. • SalB was

Clays in natural and engineered barriers for radioactive waste confinement - 5. International meeting. Book of abstracts

International Nuclear Information System (INIS)

2012-10-01

The purpose of this fifth international meeting is to bring again together specialists in the different disciplines related to clays and clay minerals, with scientists from organizations engaged in disposal of radioactive waste in order to evaluate the progress of the research conducted in that field. Multidisciplinary approaches including geology, mineralogy, geochemistry, rheology, physics and chemistry of clay minerals and assemblages are required in order to provide a detailed characterization of the geological host formations considered for the disposal of radioactive waste and to assess the behaviour of engineered and natural barriers when submitted to various types of perturbations induced by such facilities. The evaluation of the performances of the natural barrier as well as of the impact of repository-induced disturbances upon the confinement properties of clay-rich geological formations constitute major objectives for the experimental programs being and/or to be conducted in underground research laboratories, for interpreting the subsequent scientific results, for modelling the long-term behaviour of radioactive waste repositories and carrying out safety assessment exercises. The meeting covers all the aspects of clay characterization and behaviour considered at various times and space scales relevant to confinement of radionuclides in clay from basic phenomenological processes description, to the global understanding of the performance and safety at repository and geological scales. Special emphasis will be put on the modelling of processes occurring at the mineralogical level within the clay barriers. The topics covered by the program of the meeting are also supposed to be coherent with the general objectives proposed within the Strategic Research Agenda elaborated through the Implementing Geological Disposal of Radioactive Waste Technology Platform (IGD-TP). In this context, the meeting will also offer a particular opportunity to present the more

Mass spectrometry for the biophysical characterization of therapeutic monoclonal antibodies.

Science.gov (United States)

Zhang, Hao; Cui, Weidong; Gross, Michael L

2014-01-21

Monoclonal antibodies (mAbs) are powerful therapeutics, and their characterization has drawn considerable attention and urgency. Unlike small-molecule drugs (150-600 Da) that have rigid structures, mAbs (∼150 kDa) are engineered proteins that undergo complicated folding and can exist in a number of low-energy structures, posing a challenge for traditional methods in structural biology. Mass spectrometry (MS)-based biophysical characterization approaches can provide structural information, bringing high sensitivity, fast turnaround, and small sample consumption. This review outlines various MS-based strategies for protein biophysical characterization and then reviews how these strategies provide structural information of mAbs at the protein level (intact or top-down approaches), peptide, and residue level (bottom-up approaches), affording information on higher order structure, aggregation, and the nature of antibody complexes. Copyright © 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

77 FR 17570 - Art Advisory Panel-Notice of Closed Meeting

Science.gov (United States)

2012-03-26

... DEPARTMENT OF THE TREASURY Internal Revenue Service Art Advisory Panel--Notice of Closed Meeting AGENCY: Internal Revenue Service, Treasury. ACTION: Notice of Closed Meeting of Art Advisory Panel. SUMMARY: Closed meeting of the Art Advisory Panel for Fine Art will be held in New York, NY. DATES: The...

Tenth meeting of the International Working Group on Nuclear Power Plant Control and Instrumentation, Vienna, 3-5 March 1986

International Nuclear Information System (INIS)

1986-07-01

The meeting of the International Working Group on Nuclear Power Plant Control and Instrumentation (IWG-NPPCI) was organized in order to summarize operating experience of NPP control systems, gain a general overview of activities in development of modern control systems and receive recommendations on the further directions and particular measures within the Agency's programme. The papers and discussions mostly dealt with practical experience and described actual problems encountered. Emphasis was placed on the technical, industrial and economic aspects of the introduction of modern, highly automated control systems and on the improvement of plant availability and safety. A separate abstract was prepared for each of the 20 presentations of the meeting

Research in theoretical radiobiology and radiological physics: Final technical report, May 1, 1986-December 31, 1987

International Nuclear Information System (INIS)

Rossi, H.H.

1987-12-01

The work carried out under this Grant included continuation of experimental research in radiation biophysics that was previously initiated, as well as extensive theoretical efforts primarily devoted to the further development of the Theory of Dual Radiation Action. Documents for international and national organizations were prepared or evaluated. Attendance at a number of international and national meetings and scientific correspondence were also in part supported by this grant. 14 refs

Synchrotron radiation applications in biophysics and medicine

International Nuclear Information System (INIS)

Burattini, E.

1985-01-01

The peculiar properties of synchrotron radiation are briefly summarized. A short review on the possible applications of synchrotron radiation in two important fields like Biophysics and Medicine is presented. Details are given on experiments both in progress and carried out in many synchrotron radiation facilities, all over the world, using different techniques like X-ray absorption and fluorescence spectroscopy, X-ray fluorescence microanalysis, X-ray microscopy and digital subtraction angiography. Some news about the photon-activation therapy are briefly reported too

Short-Term Memory and Its Biophysical Model

Science.gov (United States)

Wang, Wei; Zhang, Kai; Tang, Xiao-wei

1996-12-01

The capacity of short-term memory has been studied using an integrate-and-fire neuronal network model. It is found that the storage of events depend on the manner of the correlation between the events, and the capacity is dominated by the value of after-depolarization potential. There is a monotonic increasing relationship between the value of after-depolarization potential and the memory numbers. The biophysics relevance of the network model is discussed and different kinds of the information processes are studied too.

Agri‐environmental Policies to Meet Consumer Preferences in Japan: An Economic‐Biophysical Model Approach

Directory of Open Access Journals (Sweden)

Tetsuya Uetake

2014-08-01

Full Text Available Promoting environmentally friendly farming products is crucial to meeting consumer demand. Although governments implement policy measures to improve the environmental performance of the agriculture sector, theirimpacts are difficult to assess. This study analyses the performance of agri‐environmental policies in Japan, by using the OECD’s policy impact model and reference level framework. In particular, it identifies the environmental impacts of three simulated agri‐environmental policies based on farms’ characteristics. The results suggest that a policy mix of regulation and an incentive payment would reduce environmental impacts, suggesting that targeted approaches could improve the cost‐effectiveness of agri‐environmental policies.

NATO Foreign Ministers December 2017 Meeting : What will emerge from NATO’s December meeting?

NARCIS (Netherlands)

Haar, Roberta

2017-01-01

What are the prospects of anything concrete emerging from the recent Foreign Ministers meeting at NATO Headquarters in Brussels? Should we anticipate that ministers attending the meeting will be able to build broad international support for any policies that might advance the alliance’s interests in

Coordination of the international network of nuclear structure and decay data evaluators. Summary report of an IAEA advisory group meeting

International Nuclear Information System (INIS)

Muir, D.W.; Pronyaev, V.G.

1998-03-01

The international network of nuclear structure and decay data (NSDD) evaluators aims at a complete and periodic nuclear structure and decay data evaluation of all nuclides, the continuous publication of these evaluations and their dissemination to the scientific community. The evaluated data resulting from this concerted international effort are introduced in the Evaluated Structure and Decay Data File (ENSDF) and published in the journals Nuclear Physics A and Nuclear Data Sheets. Periodic meetings of this network are held in order to maintain the coordination of all centres and groups participating in the compilation, evaluation and dissemination of NSDD, to maintain and improve the standards and rules governing NSDS evaluation, and to review the development and common use of the computerized systems and databases maintained specifically for this activity. This document is a summary report of the twelfth Meeting on the Coordination of the NSDD Evaluators held between 14-18 October 1996 in Budapest, Hungary

Enhancing the biophysical properties of mRFP1 through incorporation of fluoroproline

Energy Technology Data Exchange (ETDEWEB)

Deepankumar, Kanagavel; Nadarajan, Saravanan Prabhu; Ayyadurai, Niraikulam; Yun, Hyungdon, E-mail: hyungdon@ynu.ac.kr

2013-11-01

Graphical abstract: Enhancing the biophysical properties of mRFP1 through incorporation of (2S, 4R)-4-fluoroproline at proline residues after mutating non-permissive site Pro63 into Ala. -- Highlights: •We incorporate (4S)-FP into mRFP1 led to insoluble protein. •Whereas, incorporation of (4R)-FP resulted in soluble but lost its fluorescence. •mRFP1-P63A mutant accommodate (4R)-FP and gave soluble protein with fluorescence. •Moreover mRFP1-P63A[(4R)-FP] showed enhanced biophysical properties of protein. -- Abstract: Here we enhanced the stability and biophysical properties of mRFP1 through a combination of canonical and non-canonical amino acid mutagenesis. The global replacement of proline residue with (2S, 4R)-4-fluoroproline [(4R)-FP] into mRFP1 led to soluble protein but lost its fluorescence, whereas (2S, 4S)-4-fluoroproline [(4S)-FP] incorporation resulted in insoluble protein. The bioinformatics analysis revealed that (4R)-FP incorporation at Pro63 caused fluorescence loss due to the steric hindrance of fluorine atom of (4R)-FP with the chromophore. Therefore, Pro63 residue was mutated with the smallest amino acid Ala to maintain non coplanar conformation of the chromophore and helps to retain its fluorescence with (4R)-FP incorporation. The incorporation of (4R)-FP into mRFP1-P63A showed about 2–3-fold enhancement in thermal and chemical stability. The rate of maturation is also greatly accelerated over the presence of (4R)-FP into mRFP1-P63A. Our study showed that a successful enhancement in the biophysical property of mRFP1-P63A[(4R)-FP] using non-canonical amino acid mutagenesis after mutating non-permissive site Pro63 into Ala.

Materials science and biophysics applications at the ISOLDE radioactive ion beam facility

Energy Technology Data Exchange (ETDEWEB)

Wahl, U., E-mail: uwahl@itn.pt [Instituto Tecnologico e Nuclear, Estrada Nacional 10, 2686-953 Sacavem (Portugal); Centro de Fisica Nuclear da Universidade de Lisboa, Av. Prof. Gama Pinto 2, 1649-003 Lisboa (Portugal)

2011-12-15

The ISOLDE isotope separator facility at CERN provides a variety of radioactive ion beams, currently more than 800 different isotopes from {approx}70 chemical elements. The radioisotopes are produced on-line by nuclear reactions from a 1.4 GeV proton beam with various types of targets, outdiffusion of the reaction products and, if possible, chemically selective ionisation, followed by 60 kV acceleration and mass separation. While ISOLDE is mainly used for nuclear and atomic physics studies, applications in materials science and biophysics account for a significant part (currently {approx}15%) of the delivered beam time, requested by 18 different experiments. The ISOLDE materials science and biophysics community currently consists of {approx}80 scientists from more than 40 participating institutes and 21 countries. In the field of materials science, investigations focus on the study of semiconductors and oxides, with the recent additions of nanoparticles and metals, while the biophysics studies address the toxicity of metal ions in biological systems. The characterisation methods used are typical radioactive probe techniques such as Moessbauer spectroscopy, perturbed angular correlation, emission channeling, and tracer diffusion studies. In addition to these 'classic' methods of nuclear solid state physics, also standard semiconductor analysis techniques such as photoluminescence or deep level transient spectroscopy profit from the application of radioactive isotopes, which helps them to overcome their chemical 'blindness' since the nuclear half life of radioisotopes provides a signal that changes in time with characteristic exponential decay or saturation curves. In this presentation an overview will be given on the recent research activities in materials science and biophysics at ISOLDE, presenting some of the highlights during the last five years, together with a short outlook on the new developments under way.

Enhancing the biophysical properties of mRFP1 through incorporation of fluoroproline

International Nuclear Information System (INIS)

Deepankumar, Kanagavel; Nadarajan, Saravanan Prabhu; Ayyadurai, Niraikulam; Yun, Hyungdon

2013-01-01

Graphical abstract: Enhancing the biophysical properties of mRFP1 through incorporation of (2S, 4R)-4-fluoroproline at proline residues after mutating non-permissive site Pro63 into Ala. -- Highlights: •We incorporate (4S)-FP into mRFP1 led to insoluble protein. •Whereas, incorporation of (4R)-FP resulted in soluble but lost its fluorescence. •mRFP1-P63A mutant accommodate (4R)-FP and gave soluble protein with fluorescence. •Moreover mRFP1-P63A[(4R)-FP] showed enhanced biophysical properties of protein. -- Abstract: Here we enhanced the stability and biophysical properties of mRFP1 through a combination of canonical and non-canonical amino acid mutagenesis. The global replacement of proline residue with (2S, 4R)-4-fluoroproline [(4R)-FP] into mRFP1 led to soluble protein but lost its fluorescence, whereas (2S, 4S)-4-fluoroproline [(4S)-FP] incorporation resulted in insoluble protein. The bioinformatics analysis revealed that (4R)-FP incorporation at Pro63 caused fluorescence loss due to the steric hindrance of fluorine atom of (4R)-FP with the chromophore. Therefore, Pro63 residue was mutated with the smallest amino acid Ala to maintain non coplanar conformation of the chromophore and helps to retain its fluorescence with (4R)-FP incorporation. The incorporation of (4R)-FP into mRFP1-P63A showed about 2–3-fold enhancement in thermal and chemical stability. The rate of maturation is also greatly accelerated over the presence of (4R)-FP into mRFP1-P63A. Our study showed that a successful enhancement in the biophysical property of mRFP1-P63A[(4R)-FP] using non-canonical amino acid mutagenesis after mutating non-permissive site Pro63 into Ala

Chiropractic biophysics technique: a linear algebra approach to posture in chiropractic.

Science.gov (United States)

Harrison, D D; Janik, T J; Harrison, G R; Troyanovich, S; Harrison, D E; Harrison, S O

1996-10-01

This paper discusses linear algebra as applied to human posture in chiropractic, specifically chiropractic biophysics technique (CBP). Rotations, reflections and translations are geometric functions studied in vector spaces in linear algebra. These mathematical functions are termed rigid body transformations and are applied to segmental spinal movement in the literature. Review of the literature indicates that these linear algebra concepts have been used to describe vertebral motion. However, these rigid body movers are presented here as applying to the global postural movements of the head, thoracic cage and pelvis. The unique inverse functions of rotations, reflections and translations provide a theoretical basis for making postural corrections in neutral static resting posture. Chiropractic biophysics technique (CBP) uses these concepts in examination procedures, manual spinal manipulation, instrument assisted spinal manipulation, postural exercises, extension traction and clinical outcome measures.

Radiation biophysics in space

International Nuclear Information System (INIS)

Buecker, H.; Horneck, G.

1983-01-01

In a demonstration experiment bacterium sporules have been exposed to the space vacuum and to the solar radiation field at 254 nm, with the following results: 1) a short vacuum exposition of 1.3 h does not affect the vitality of the sporules, 2) the survival rate of humid sporules after UV-irradiation is consistent with terrestrial control samples, 3) after a simultaneous exposition to vacuum and solar UV-radiation the effect on the sporules is enhanced by a factor of ten as compared to the situation without vaccum exposition. Additional studies in biophysical simulation systems revealed, that the enhanced UV sensitivity is caused by the dehydration of the sporules. By this process the structure of the essential macromolecules in cell, such as DNA and proteins, is modified such that new photo-products can be formed. For these products the cells have no effective repair systems. (AJ) [de

International topical meeting TOPSEAL 2006. Transactions

International Nuclear Information System (INIS)

2006-01-01

From 17-20 September 2006, over 100 nuclear scientists and engineers from across Europe, Canada, the USA, Japan and Korea converged on the Olkiluoto Information Centre in Finland to attend TOPSEAL 2006. This international topical meeting dedicated to the subject of radioactive waste management was organised by the European Nuclear Society (ENS) in co-operation with the Finnish Nuclear Society (ATS) and the OECD/NEA. The conference was hosted by TVO, Finland's largest power utility and POSIVA, a daughter company of TVO and the country's number one radioactive waste management specialist. The main message that emerged from the conference is that a range of technological solutions exist and are currently being developed and applied across Europe - and beyond - to ensure the safe and efficient long term management of all categories of nuclear waste and spent fuel. Against the background of the nuclear revival, more and more countries are now looking closely at all available options. The TOPSEAL 2006 agenda centred upon four main sessions devoted respectively to: international perspectives on radioactive waste management; research, development and demonstration of waste storage and disposal; existing experiences with low and intermediate level radioactive waste and deep geological and near surface repositories. The conference concluded with a panel discussion entitled Future Challenges in radioactive Waste Management and a visit of the waste management facilities in Olkiluoto. Among the many issues discussed by TOPSEAL delegates was EU policy and legislation related to waste management, deep underground repositories, near surface storage, the experimental modelling of safety barriers, radiation shielding and research funding. Research and development programmes, benchmarking and long term strategies in several countries were also presented and discussed at length. A recurring theme that underpinned the discussions was the need to increase public understanding and

Review of the 25th annual scientific meeting of the International Society for Biological Therapy of Cancer.

Science.gov (United States)

Balwit, James M; Kalinski, Pawel; Sondak, Vernon K; Coulie, Pierre G; Jaffee, Elizabeth M; Gajewski, Thomas F; Marincola, Francesco M

2011-05-12

Led by key opinion leaders in the field, the 25th Annual Meeting of the International Society for Biological Therapy of Cancer (iSBTc, recently renamed the Society for Immunotherapy of Cancer, SITC) provided a scientific platform for ~500 attendees to exchange cutting-edge information on basic, clinical, and translational research in cancer immunology and immunotherapy. The meeting included keynote addresses on checkpoint blockade in cancer therapy and recent advances in therapeutic vaccination against cancer induced by Human Papilloma Virus 16. Participants from 29 countries interacted through oral presentations, panel discussions, and posters on topics that included dendritic cells and cancer, targeted therapeutics and immunotherapy, innate/adaptive immune interplay in cancer, clinical trial endpoints, vaccine combinations, countering negative regulation, immune cell trafficking to tumor microenvironment, and adoptive T cell transfer. In addition to the 50 oral presentations and >180 posters on these topics, a new SITC/iSBTc initiative to create evidence-based Cancer Immunotherapy Guidelines was announced. The SITC/iSBTc Biomarkers Taskforce announced the release of recommendations on immunotherapy biomarkers and a highly successful symposium on Immuno-Oncology Biomarkers that took place on the campus of the National Institutes of Health (NIH) immediately prior to the Annual Meeting. At the Annual Meeting, the NIH took the opportunity to publicly announce the award of the U01 grant that will fund the Cancer Immunotherapy Trials Network (CITN). In summary, the Annual Meeting gathered clinicians and scientists from academia, industry, and regulatory agencies from around the globe to interact and exchange important scientific advances related to tumor immunobiology and cancer immunotherapy.

Perspectives and Plans for Graduate Studies. 16. Biophysics 1974.

Science.gov (United States)

Ontario Council on Graduate Studies, Toronto. Advisory Committee on Academic Planning.

In March, 1973, after a review of the Ontario universities' three-year plans, a provisional embargo was placed on doctoral work in biophysics. A full-scale assessment with outside consultants was not necessary in the case of a provisional embargo. Instead, the method used to remove the embargo was self-study by the discipline group leading to a…

Southwest Ecological Restoration Institutes (SWERI) Biophysical Monitoring Workshop Report

Science.gov (United States)

Joseph Seidenberg; Judy Springer; Tessa Nicolet; Mike Battaglia; Christina Vothja

2009-01-01

On October 15-16, 2009, the Southwest Ecological Restoration Institutes (SWERI) hosted a workshop in which the participants would 1) build a common understanding of the types of monitoring that are occurring in forested ecosystems of the Southwest; 2) analyze and agree on an efficient, yet robust set of biophysical variables that can be used by land mangers and...

Biophysical and electrochemical studies of protein-nucleic acid interactions

Czech Academy of Sciences Publication Activity Database

Bowater, R. P.; Cobb, A:M.; Pivoňková, Hana; Havran, Luděk; Fojta, Miroslav

2015-01-01

Roč. 146, č. 5 (2015), s. 723-739 ISSN 0026-9247 R&D Projects: GA ČR(CZ) GBP206/12/G151; GA ČR(CZ) GAP301/11/2076 Institutional support: RVO:68081707 Keywords : ISOTHERMAL TITRATION CALORIMETRY * OSMIUM-TETROXIDE COMPLEXES * SURFACE-PLASMON RESONANCE Subject RIV: BO - Biophysics Impact factor: 1.131, year: 2015

International Conference Nuclear Energy in Central Europe 99, V. 2. Proceedings. Embedded Meeting Neutron Imaging Methods to Detect Defects in Materials

International Nuclear Information System (INIS)

Gortnar, O.; Stritar, A.

1999-01-01

International Conference Nuclear Energy in Central Europe is an annual meeting of the Nuclear Society of Slovenia. The second book of proceedings contain 14 articles from Slovenia, surrounding countries and countries of the Central and Eastern European Region. Topics cover Neutron Imaging Methods

Second Annual Meeting of the International Society of Pediatric Wound Care.

Science.gov (United States)

Keswani, Sundeep G

2015-10-01

The overarching goals of the International Society of Pediatric Wound Care (ISPeW) are to (1) set global standards for the assessment and treatment of pediatric wounds of varying etiologies; (2) provide a forum for international interprofessional collaboration among healthcare professionals, researchers, educators, and industry leaders dedicated to the care of pediatric wounds; (3) promote and support clinical research focused on the prevention, assessment, and treatment of pediatric wounds; (4) collaborate with wound care organizations worldwide on pediatric wound care issues; and (5) provide evidence-based pediatric wound care education to healthcare professionals, parents, and lay caregivers. This edition of Advances in Wound Care includes some of the work that was presented at the 2014 ISPeW meeting in Rome. The first article by Dr. Romanelli, is an in-depth description of the progression of skin physiology throughout its maturational stages and clinical implication. A cutting edge article by Dr. Timothy King then follows, with regard to scar prevention in postnatal tissues. This is followed by a comprehensive look at debridement techniques in pediatric trauma by Dr. Ankush Gosain. Next, is a cautionary article by Dr. Luca Spazzapan that examines the prevalence of diabetic foot ulcers in children and the potential for an epidemic. The last article in this series is from the keynote speaker, Dr. Amit Geffen, who eloquently examines the use of biomaterials to offload and prevent pediatric pressure ulcers.

Sixth coordination meeting of the Division of Nuclear Physics Program to meet high-priority nuclear data needs of the Office of Fusion Energy

International Nuclear Information System (INIS)

1990-06-01

The Sixth Coordination Meeting of the Program to Meet Nuclear Data Needs for Fusion Energy was held in Athens, September 19--21, 1989. The principal change from the previous meeting at Argonne was the larger international participation. One scientist from Japan represented the only non-US participation at Argonne. The present meeting included about 20% non-US participants. This change is a welcome one since the data needs are international and the limited availability of manpower and facilities will likely make international cooperation increasingly important in the future. The organization of the meeting involved collecting and distributing to all participants progress reports from the Department of Energy laboratories in advance of the meeting. Twenty-five oral presentations were made at the meeting, including many from non-DOE labs. The meeting then divided into experimental and theoretical task force groups, which carried out assigned agenda items. The reports of these groups, abstracts of the talks presented at the meeting, and the progress reports are included in this report. The topics discussed will be very familiar to participants in past meetings, but continued progress in most areas was reported. One discussion topic which reflects continuing and perhaps worsening problems was the aging of facilities and personnel, coupled with a lack of programs to renew

International Meeting on Needs and Challenges in Translational Medicine: filling the gap between basic research and clinical applications. Book of abstract

International Nuclear Information System (INIS)

Moretti, F.; Belardelli, F.; Romero, M.

2008-01-01

This multidisciplinary international meeting is organized by the Istituto Superiore di Sanita, in collaboration with Alleanza Contro il Cancro (Alliance Against Cancer, the Network of the Italian Comprehensive Cancer Centres) and EATRIS (European Advanced Translational Research Infrastructure in Medicine). The primary goal of the meeting is to provide a scientific forum to discuss the recent progress in translational research. Moreover, a particular focus will be devoted to the identification of needs, obstacles and new opportunities to promote translational research in biomedicine. The scientific programme will cover a broad range of fields including: cancer; neurosciences; rare diseases; cardiovascular diseases and infectious and autoimmune diseases. Furthermore, special attention will be given to the discussion of how comprehensive initiatives for addressing critical regulatory issues for First-In-Man - Phase I clinical studies can potentially improve the efficiency and quality of biomedical and translational research at an international level [it

International Conference on Advances in Radiation Oncology (ICARO): outcomes of an IAEA meeting.

Science.gov (United States)

Salminen, Eeva K; Kiel, Krystyna; Ibbott, Geoffrey S; Joiner, Michael C; Rosenblatt, Eduardo; Zubizarreta, Eduardo; Wondergem, Jan; Meghzifene, Ahmed

2011-02-04

The IAEA held the International Conference on Advances in Radiation Oncology (ICARO) in Vienna on 27-29 April 2009. The Conference dealt with the issues and requirements posed by the transition from conventional radiotherapy to advanced modern technologies, including staffing, training, treatment planning and delivery, quality assurance (QA) and the optimal use of available resources. The current role of advanced technologies (defined as 3-dimensional and/or image guided treatment with photons or particles) in current clinical practice and future scenarios were discussed.ICARO was organized by the IAEA at the request of the Member States and co-sponsored and supported by other international organizations to assess advances in technologies in radiation oncology in the face of economic challenges that most countries confront. Participants submitted research contributions, which were reviewed by a scientific committee and presented via 46 lectures and 103 posters. There were 327 participants from 70 Member States as well as participants from industry and government. The ICARO meeting provided an independent forum for the interaction of participants from developed and developing countries on current and developing issues related to radiation oncology.

International Conference on Advances in Radiation Oncology (ICARO: Outcomes of an IAEA Meeting

Directory of Open Access Journals (Sweden)

Wondergem Jan

2011-02-01

Full Text Available Abstract The IAEA held the International Conference on Advances in Radiation Oncology (ICARO in Vienna on 27-29 April 2009. The Conference dealt with the issues and requirements posed by the transition from conventional radiotherapy to advanced modern technologies, including staffing, training, treatment planning and delivery, quality assurance (QA and the optimal use of available resources. The current role of advanced technologies (defined as 3-dimensional and/or image guided treatment with photons or particles in current clinical practice and future scenarios were discussed. ICARO was organized by the IAEA at the request of the Member States and co-sponsored and supported by other international organizations to assess advances in technologies in radiation oncology in the face of economic challenges that most countries confront. Participants submitted research contributions, which were reviewed by a scientific committee and presented via 46 lectures and 103 posters. There were 327 participants from 70 Member States as well as participants from industry and government. The ICARO meeting provided an independent forum for the interaction of participants from developed and developing countries on current and developing issues related to radiation oncology.

76 FR 77776 - Environmental Technologies Trade Advisory Committee Public Meeting

Science.gov (United States)

2011-12-14

... DEPARTMENT OF COMMERCE International Trade Administration Environmental Technologies Trade... meeting of the Environmental Technologies Trade Advisory Committee (ETTAC). DATES: The meeting is... Energy & Environmental Industries (OEEI), International Trade Administration, Room 4053, 1401...

76 FR 51001 - Environmental Technologies Trade Advisory Committee Public Meeting

Science.gov (United States)

2011-08-17

... DEPARTMENT OF COMMERCE International Trade Administration Environmental Technologies Trade... meeting of the Environmental Technologies Trade Advisory Committee (ETTAC). DATES: The meeting is... Energy & Environmental Industries (OEEI), International Trade Administration, Room 4053, 1401...

77 FR 58356 - Environmental Technologies Trade Advisory Committee Public Meeting

Science.gov (United States)

2012-09-20

... DEPARTMENT OF COMMERCE International Trade Administration Environmental Technologies Trade... meeting of the Environmental Technologies Trade Advisory Committee (ETTAC). DATES: The meeting is... Energy & Environmental Industries (OEEI), International Trade Administration, Room 4053, 1401...

78 FR 4834 - Environmental Technologies Trade Advisory Committee Public Meeting

Science.gov (United States)

2013-01-23

... DEPARTMENT OF COMMERCE International Trade Administration Environmental Technologies Trade... meeting of the Environmental Technologies Trade Advisory Committee (ETTAC). DATES: The meeting is... Energy & Environmental Industries (OEEI), International Trade Administration, Room 4053, 1401...

From hadron therapy to cosmic rays: a life in biophysics

CERN Multimedia

Christine Sutton

2014-01-01

In 1954 – the year CERN was founded – another scientific journey began at what is now the Lawrence Berkeley National Laboratory. Beams of protons from a particle accelerator were used for the first time by John Lawrence – a doctor and the brother of Ernest Lawrence, the physicist after whom the Berkeley lab is named – to treat patients with cancer. For many years, Eleanor Blakely has been one of the leaders of that journey. She visited CERN last week and spoke with the Bulletin about her life in biophysics.   Use of the cylcotron beam to mimic "shooting stars" seen by astronauts. Black hood on subject Cornelius Tobias keeps out light during neutron irradiation experiment at the 184-inch accelerator. Helping to position Tobias in the beam line are (left to right) John Lyman of Biomedical Division, and Ralph Thomas of Health Physics. (Photo courtesy of Lawrence Berkeley National Laboratory.) Interested in biophysics, which was still a new...

Biophysical mechanisms complementing "classical" cell biology.

Science.gov (United States)

Funk, Richard H W

2018-01-01

This overview addresses phenomena in cell- and molecular biology which are puzzling by their fast and highly coordinated way of organization. Generally, it appears that informative processes probably involved are more on the biophysical than on the classical biochemical side. The coordination problem is explained within the first part of the review by the topic of endogenous electrical phenomena. These are found e.g. in fast tissue organization and reorganization processes like development, wound healing and regeneration. Here, coupling into classical biochemical signaling and reactions can be shown by modern microscopy, electronics and bioinformatics. Further, one can follow the triggered reactions seamlessly via molecular biology till into genetics. Direct observation of intracellular electric processes is very difficult because of e.g. shielding through the cell membrane and damping by other structures. Therefore, we have to rely on photonic and photon - phonon coupling phenomena like molecular vibrations, which are addressed within the second part. Molecules normally possess different charge moieties and thus small electromagnetic (EMF) patterns arise during molecular vibration. These patterns can now be measured best within the optical part of the spectrum - much less in the lower terahertz till kHz and lower Hz part (third part of this review). Finally, EMFs facilitate quantum informative processes in coherent domains of molecular, charge and electron spin motion. This helps to coordinate such manifold and intertwined processes going on within cells, tissues and organs (part 4). Because the phenomena described in part 3 and 4 of the review still await really hard proofs we need concerted efforts and a combination of biophysics, molecular biology and informatics to unravel the described mysteries in "physics of life".

Trade and Development: Proceedings of the Winter 1986 Meeting of the International Agricultural Trade Research Consortium (Texcoco, Mexico, December 1986).

Science.gov (United States)

Shane, Mathew D., Ed.

Three levels of papers are contained in this proceedings. The first set contains full research papers presented during the theme day of the meeting. The following papers were given: "International Trade and Factor Movements in Development Theory, Policy, and Experience" (T. N. Srinivasan); "Government in the Process of Trade and…

Social and Biophysical Predictors of Public Perceptions of Extreme Fires

Science.gov (United States)

Hall, T. E.; Kooistra, C. M.; Paveglio, T.; Gress, S.; Smith, A. M.

2013-12-01

To date, what constitutes an 'extreme' fire has been approached separately by biophysical and social scientists. Research on the biophysical characteristics of fires has identified potential dimensions of extremity, including fire size and vegetation mortality. On the social side, factors such as the degree of immediate impact to one's life and property or the extent of social disruption in the community contribute to a perception of extremity. However, some biophysical characteristics may also contribute to perceptions of extremity, including number of simultaneous ignitions, rapidity of fire spread, atypical fire behavior, and intensity of smoke. Perceptions of these impacts can vary within and across communities, but no studies to date have investigated such perceptions in a comprehensive way. In this study, we address the question, to what extent is the magnitude of impact of fires on WUI residents' well-being explained by measurable biophysical characteristics of the fire and subjective evaluations of the personal and community-level impacts of the fire? We bring together diverse strands of psychological theory, including landscape perception, mental models, risk perception, and community studies. The majority of social science research on fires has been in the form of qualitative case studies, and our study is methodologically unique by using a nested design (hierarchical modeling) to enable generalizable conclusions across a wide range of fires and human communities. We identified fires that burned in 2011 or 2012 in the northern Rocky Mountain region that were at least 1,000 acres and that intersected (within 15 km) urban clusters or identified Census places. For fires where an adequately large number of households was located in proximity to the fire, we drew random samples of approximately 150 individuals for each fire. We used a hybrid internet (Qualtrics) and mail survey, following the Dillman method, to measure individual perceptions. We developed two

Summary Record of the Twenty-Sixth Meeting of the Working Party on International Nuclear Data Evaluation Co-operation

International Nuclear Information System (INIS)

Dupont, Emmeric

2014-01-01

The NEA's nuclear data evaluation co-operation activities involve the following evaluation projects: ENDF (United States), JENDL (Japan), ROSFOND/BROND (Russia), JEFF (other Data Bank member countries) and CENDL (China) in close co-operation with the Nuclear Data Section of the International Atomic Energy Agency (IAEA). The working party was established to promote the exchange of information on nuclear data evaluations, measurements, nuclear model calculations, validation, and related topics, and to provide a framework for co-operative activities between the participating projects. The working party assesses nuclear data improvement needs and addresses these needs by initiating joint evaluation and/or measurement efforts. This document is the executive summary of WPEC's 26. meeting held in 2014. It presents a brief review of the 2 days meeting in particular the Reports on experimental activities in Europe, Japan, USA and China, the Brief progress reports from the evaluation projects (ENDF, JEFF, JENDL, ROSFOND, CENDL, IAEA, TENDL) with the discussion of future plans, the Review of final or near-final subgroup reports, the Status of ongoing subgroups, the Proposals for new subgroups and some information about Conferences and meetings of interest to the nuclear data community. A list of participants and a list of reports presented at this meeting are attached in appendix

International nuclear fuel cycle evaluation

International Nuclear Information System (INIS)

Witt, P.

1980-01-01

In the end of February 1980, the two-years work on the International Nuclear Fuel Cycle Evaluation (INFCE) was finished in Vienna with a plenary meeting. INFCE is likely to have been a unique event in the history of international meetings: It was ni diplomatic negotiation meeting, but a techno-analytical investigation in which the participants tenaciously shuggled for many of the formulations. Starting point had been a meeting initiated by President Carter in Washington in Oct. 1979 after the World Economy Summit Meeting in London. The results of the investigation are presented here in a brief and popular form. (orig./UA) [de

BIOPHYSICAL PROPERTIES OF NUCLEIC ACIDS AT SURFACES RELEVANT TO MICROARRAY PERFORMANCE.

Science.gov (United States)

Rao, Archana N; Grainger, David W

2014-04-01

Both clinical and analytical metrics produced by microarray-based assay technology have recognized problems in reproducibility, reliability and analytical sensitivity. These issues are often attributed to poor understanding and control of nucleic acid behaviors and properties at solid-liquid interfaces. Nucleic acid hybridization, central to DNA and RNA microarray formats, depends on the properties and behaviors of single strand (ss) nucleic acids (e.g., probe oligomeric DNA) bound to surfaces. ssDNA's persistence length, radius of gyration, electrostatics, conformations on different surfaces and under various assay conditions, its chain flexibility and curvature, charging effects in ionic solutions, and fluorescent labeling all influence its physical chemistry and hybridization under assay conditions. Nucleic acid (e.g., both RNA and DNA) target interactions with immobilized ssDNA strands are highly impacted by these biophysical states. Furthermore, the kinetics, thermodynamics, and enthalpic and entropic contributions to DNA hybridization reflect global probe/target structures and interaction dynamics. Here we review several biophysical issues relevant to oligomeric nucleic acid molecular behaviors at surfaces and their influences on duplex formation that influence microarray assay performance. Correlation of biophysical aspects of single and double-stranded nucleic acids with their complexes in bulk solution is common. Such analysis at surfaces is not commonly reported, despite its importance to microarray assays. We seek to provide further insight into nucleic acid-surface challenges facing microarray diagnostic formats that have hindered their clinical adoption and compromise their research quality and value as genomics tools.

BIOPHYSICAL PROPERTIES OF NUCLEIC ACIDS AT SURFACES RELEVANT TO MICROARRAY PERFORMANCE

Science.gov (United States)

Rao, Archana N.; Grainger, David W.

2014-01-01

Both clinical and analytical metrics produced by microarray-based assay technology have recognized problems in reproducibility, reliability and analytical sensitivity. These issues are often attributed to poor understanding and control of nucleic acid behaviors and properties at solid-liquid interfaces. Nucleic acid hybridization, central to DNA and RNA microarray formats, depends on the properties and behaviors of single strand (ss) nucleic acids (e.g., probe oligomeric DNA) bound to surfaces. ssDNA’s persistence length, radius of gyration, electrostatics, conformations on different surfaces and under various assay conditions, its chain flexibility and curvature, charging effects in ionic solutions, and fluorescent labeling all influence its physical chemistry and hybridization under assay conditions. Nucleic acid (e.g., both RNA and DNA) target interactions with immobilized ssDNA strands are highly impacted by these biophysical states. Furthermore, the kinetics, thermodynamics, and enthalpic and entropic contributions to DNA hybridization reflect global probe/target structures and interaction dynamics. Here we review several biophysical issues relevant to oligomeric nucleic acid molecular behaviors at surfaces and their influences on duplex formation that influence microarray assay performance. Correlation of biophysical aspects of single and double-stranded nucleic acids with their complexes in bulk solution is common. Such analysis at surfaces is not commonly reported, despite its importance to microarray assays. We seek to provide further insight into nucleic acid-surface challenges facing microarray diagnostic formats that have hindered their clinical adoption and compromise their research quality and value as genomics tools. PMID:24765522

Biophysical Approach to Mechanisms of Cancer Prevention and Treatment with Green Tea Catechins.

Science.gov (United States)

Suganuma, Masami; Takahashi, Atsushi; Watanabe, Tatsuro; Iida, Keisuke; Matsuzaki, Takahisa; Yoshikawa, Hiroshi Y; Fujiki, Hirota

2016-11-18

Green tea catechin and green tea extract are now recognized as non-toxic cancer preventives for humans. We first review our brief historical development of green tea cancer prevention. Based on exciting evidence that green tea catechin, (-)-epigallocatechin gallate (EGCG) in drinking water inhibited lung metastasis of B16 melanoma cells, we and other researchers have studied the inhibitory mechanisms of metastasis with green tea catechins using biomechanical tools, atomic force microscopy (AFM) and microfluidic optical stretcher. Specifically, determination of biophysical properties of cancer cells, low cell stiffness, and high deformability in relation to migration, along with biophysical effects, were studied by treatment with green tea catechins. The study with AFM revealed that low average values of Young's moduli, indicating low cell stiffness, are closely associated with strong potential of cell migration and metastasis for various cancer cells. It is important to note that treatments with EGCG and green tea extract elevated the average values of Young's moduli resulting in increased stiffness (large elasticity) of melanomas and various cancer cells. We discuss here the biophysical basis of multifunctions of green tea catechins and green tea extract leading to beneficial effects for cancer prevention and treatment.

Eleventh ITER negotiations meeting (N-11) and twelfth negotiators' standing sub-group meeting (NSSG-12)

International Nuclear Information System (INIS)

Luo Delong

2005-01-01

The Eleventh ITER Negotiations Meeting (N-11) and the Twelfth Negotiators' Standing Sub-Group (NSSG-12 convened on October 19-25, 2005 at the Kempinski Hotel Chengdu, Sichuan Province. China was the host of this meeting. Delegations from China, the European Union, Japan, the Republic of Korea, the Russian Federation and the United States of America, as well as members from the International Team, met there to continue their work to reach agreement on the joint implementation of the ITER international fusion energy R and D project. The delegations accepted the Vice Minister of Science and Technology, Mr. LIU Yanhua, and State Councillor, Mr. SHI Dinghuan as Moderators for N-11 and NSSG-12, respectively, and Mr. LUO Delong as Secretary for both meetings. At the Meeting, delegates discussed and made substantial progress on a full range of legal, technical, and administrative topics, including staffing for ITER, policies for managing the project and its procurements, and the continuing joint drafting of the agreement on establishing the international ITER Organization to implement the project. Delegates also explored the possibility of India joining the Negotiations. In the light of the reports presented to the Meeting from the recent joint exploratory mission to India, delegates identified a series of steps for the near future leading towards a possible agreement among all the Parties to India's accession. The Negotiations Meeting also discussed the progress report of NSSG and forward planning and future tasks. The Negotiators agreed that substantial progress was made on all topics, and delegations are optimistic that the Joint Implementation Agreement and related Annexes and instruments could be initialed in spring of 2006. As decided by all delegations, the next Twelfth ITER Negotiations Meeting will be held in Korea on 6 December, 2005

76 FR 26247 - Environmental Technologies Trade Advisory Committee Public Meeting

Science.gov (United States)

2011-05-06

... DEPARTMENT OF COMMERCE International Trade Administration Environmental Technologies Trade... meeting of the Environmental Technologies Trade Advisory Committee (ETTAC). DATES: The meeting is... & Environmental Industries (OEEI), International Trade Administration, Room 4053, 1401 Constitution Ave, NW...

78 FR 46921 - Environmental Technologies Trade Advisory Committee Public Meeting

Science.gov (United States)

2013-08-02

... DEPARTMENT OF COMMERCE International Trade Administration Environmental Technologies Trade... meeting of the Environmental Technologies Trade Advisory Committee (ETTAC). DATES: The meeting is... Hinman, Office of Energy & Environmental Industries (OEEI), International Trade Administration, Room 4053...

Structural and biophysical characteristics of human skin in maintaining proper epidermal barrier function

Directory of Open Access Journals (Sweden)

Magdalena Boer

2016-02-01

Full Text Available The complex structure of human skin and its physicochemical properties turn it into an efficient outermost defence line against exogenous factors, and help maintain homeostasis of the human body. This role is played by the epidermal barrier with its major part – stratum corneum. The condition of the epidermal barrier depends on individual and environmental factors. The most important biophysical parameters characterizing the status of this barrier are the skin pH, epidermal hydration, transepidermal water loss and sebum excretion. The knowledge of biophysical skin processes may be useful for the implementation of prophylactic actions whose aim is to restore the barrier function.

General Information Meeting on the European Co-operative Association of International Civil Servants (AMFIE)

CERN Multimedia

HR Department

2011-01-01

Monday 28 November 2011 at 12h (61/1-009 – Pas Perdus, room C) Mrs. Janine RIVALS, Vice-Chairwoman of AMFIE's* Board of Directors and Mrs. Hélène ECKERT, coordinator for all international organisations in Switzerland, will make a general presentation on AMFIE's personal financial services and how they may benefit international civil servants. They will also focus on the particular financial challenges faced by expatriate civil servants and on the solutions AMFIE can offer. The presentation will be followed by a question and answer session. Private consultations – from 11:00 to 12:00 and from 14:00 to 17:30 (61/1-009 and 61/0-006) Participants who wish to meet AMFIE's representatives for one-to-one private consultations are invited to contact directly Mrs. Janine Rivals (+33/1 45 35 70 79, GSM +33/6 63 58 36 62 or jr@amfie.org) or AMFIE's Secretariat in Luxembourg (+352/42 36 61-1 or amfie@amfie.org). It will be possible to make an ...

Nanoscale quantification of the biophysical characterization of combretastatin A-4-treated tumor cells using atomic force microscopy.

Science.gov (United States)

Li, Yanchun; Chen, Jv; Liu, Yutong; Zhang, Weige; He, Wenhui; Xu, Hanying; Liu, Lianqing; Ma, Enlong

2017-01-01

As an inhibitor of microtubule assembly, combretastatin A-4 (CA-4)-induced biological responses in tumor cells have been well known, but the corresponding changes in nano-biophysical properties were not investigated given the lack of an ideal tool. Using AFM technique, we investigated the alteration of nano-biophysical properties when CA-4-treated tumor cells underwent the different biological processes, including cell cycle arrest, apoptosis and autophagy. We found that CA-4-resistant cells were rougher with the presence of characteristic "ridges", indicating that the development of "ridge" structure may be a determinant of the sensitivity of cells to CA-4 compounds. CA-4 induced G2/M arrest and apoptosis in sensitive cells but triggered anti-apoptotic autophagy in resistant cells. CA-4 treatment caused an increase in stiffness in both sensitive and resistant cells. However, these cells exhibited different changes in cell surface roughness. CA-4 decreased Ra and Rq values in sensitive cells but increased these values in resistant cells. The reorganization of F-actin might contribute to the different changes of nano-biophysical properties in CA-4-sensitive and-resistant cells. Our results suggest that cellular nano-biophysical properties, such as "ridges", roughness and stiffness, could be applied as potential biomarkers for evaluating CA-4 compounds, and knowledge regarding how biological alterations cause changes in cellular nano-biophysical properties is helpful to develop a new high-resolution screening tool for anti-tumor agents.

Informal meeting on ITER developments

International Nuclear Information System (INIS)

Canobbio, E.

2000-01-01

The International Fusion Research Council (IFRC), advisory body of the IAEA, organized an informal meeting on the general status and outlook for ITER, held October 9 at Sorrento, Italy, in conjunction with the 18th IAEA Fusion Energy Conference. This article describes the main events at the meeting

Biophysical approach to chronic kidney disease management in older patients

Directory of Open Access Journals (Sweden)

Alberto Foletti

2016-06-01

Full Text Available Chronic kidney disease (CKD and its clinical progression are a critical issue in an aging population. Therefore, strategies aimed at preventing and managing the decline of renal function are warranted. Recent evidence has provided encouraging results for the improvement of renal function achieved through an integrated biophysical approach, but prospective studies on the clinical efficacy of this strategy are still lacking. This was an open-label prospective pilot study to investigate the effect of electromagnetic information transfer through the aqueous system on kidney function of older patients affected by stage 1 or 2 CKD. Patients received biophysical therapy every 3 months over a 1-year period. Estimated glomerular filtration rate (eGFR values were calculated using the CKD–Epidemiology Collaboration formula, and were recorded at baseline and at the end of treatment. Overall, 58 patients (mean age 74.8 ± 3.7 years were included in the study. At baseline, mean eGFR was 64.6 ± 15.5 mL/min, and it significantly increased to 69.9 ± 15.8 mL/min after 1 year (+5.2 ± 10 mL/min, p<0.0002. The same trend was observed among men (+5.7 ± 10.2 mL/min, p<0.0064 and women (+4.7 ± 9.9 mL/min, p<0.014. When results were analyzed by sex, no difference was found between the 2 groups. Although further and larger prospective studies are needed, our findings suggest that an integrated biophysical approach may be feasible in the management of older patients with early-stage CKD, to reduce and prevent the decline of renal function due to aging or comorbidities.

Photobiology of Symbiodinium revisited: bio-physical and bio-optical signatures

Science.gov (United States)

Hennige, S. J.; Suggett, D. J.; Warner, M. E.; McDougall, K. E.; Smith, D. J.

2009-03-01

Light is often the most abundant resource within the nutrient-poor waters surrounding coral reefs. Consequently, zooxanthellae ( Symbiodinium spp.) must continually photoacclimate to optimise productivity and ensure coral success. In situ coral photobiology is becoming dominated by routine assessments using state-of-the-art non-invasive bio-optical or chlorophyll a fluorescence (bio-physical) techniques. Multiple genetic types of Symbiodinium are now known to exist; however, little focus has been given as to how these types differ in terms of characteristics that are observable using these techniques. Therefore, this investigation aimed to revisit and expand upon a pivotal study by Iglesias-Prieto and Trench (1994) by comparing the photoacclimation characteristics of different Symbiodinium types based on their bio-physical (chlorophyll a fluorescence, reaction centre counts) and bio-optical (optical absorption, pigment concentrations) ‘signatures’. Signatures described here are unique to Symbiodinium type and describe phenotypic responses to set conditions, and hence are not suitable to describe taxonomic structure of in hospite Symbiodinium communities. In this study, eight Symbiodinium types from clades and sub-clades (A-B, F) were grown under two PFDs (Photon Flux Density) and examined. The photoacclimation response by Symbiodinium was highly variable between algal types for all bio-physical and for many bio-optical measurements; however, a general preference to modifying reaction centre content over effective antennae-absorption was observed. Certain bio-optically derived patterns, such as light absorption, were independent of algal type and, when considered per photosystem, were matched by reaction centre stoichiometry. Only by better understanding genotypic and phenotypic variability between Symbiodinium types can future studies account for the relative taxonomic and physiological contribution by Symbiodinium to coral acclimation.

76 FR 14003 - International Energy Agency Meetings