WorldWideScience

Sample records for integrated ips power

  1. Automated Integration of Dedicated Hardwired IP Cores in Heterogeneous MPSoCs Designed with ESPAM

    Directory of Open Access Journals (Sweden)

    Ed Deprettere

    2008-06-01

    Full Text Available This paper presents a methodology and techniques for automated integration of dedicated hardwired (HW IP cores into heterogeneous multiprocessor systems. We propose an IP core integration approach based on an HW module generation that consists of a wrapper around a predefined IP core. This approach has been implemented in a tool called ESPAM for automated multiprocessor system design, programming, and implementation. In order to keep high performance of the integrated IP cores, the structure of the IP core wrapper is devised in a way that adequately represents and efficiently implements the main characteristics of the formal model of computation, namely, Kahn process networks, we use as an underlying programming model in ESPAM. We present details about the structure of the HW module, the supported types of IP cores, and the minimum interfaces these IP cores have to provide in order to allow automated integration in heterogeneous multiprocessor systems generated by ESPAM. The ESPAM design flow, the multiprocessor platforms we consider, and the underlying programming (KPN model are introduced as well. Furthermore, we present the efficiency of our approach by applying our methodology and ESPAM tool to automatically generate, implement, and program heterogeneous multiprocessor systems that integrate dedicated IP cores and execute real-life applications.

  2. Study of transmitting electric power utility communications in IP network. Transmission of existing electric power utility communications in best effort type IP network under delay constraint; Denryokuyo tsushin kaisen no IP mo eno shuyo kento. Chien jikan seiyakuka ni okeru best effort gata IP mo eno kison denryokuyo tsushin kaisen no shuyo

    Energy Technology Data Exchange (ETDEWEB)

    Miyake, H.

    2000-07-01

    Since IP network does best effort behavior fundamentally, it always generates delay time and delay variation. For this reason, IP network has been unsuitable to transmit real time data such as a voice. However, in recent years, the technologies which transmit real time data in IP network, e.g. VoIP, have spread. If it is possible to transmit the existing electric power utility communications in IP network using these technologies, total network cost can be reduced by the reduction of required bandwidth and the simplification of communication network systems. In this report, it is examined quantitatively whether end-end delay time of the existing electric power utility communications, e.g. on-line, telephone, carrier relay, CDT (cyclic digital transmission equipment), video conference, ITV(industrial television), is within their permission delay time when they are transmitted in the best effort type IP network. (author)

  3. Integrating QoS and security functions in an IP-VPN gateway

    Science.gov (United States)

    Fan, Kuo-Pao; Chang, Shu-Hsin; Lin, Kuan-Ming; Pen, Mau-Jy

    2001-10-01

    IP-based Virtual Private Network becomes more and more popular. It can not only reduce the enterprise communication cost but also increase the revenue of the service provider. The common IP-VPN application types include Intranet VPN, Extranet VPN, and remote access VPN. For the large IP-VPN market, some vendors develop dedicated IP-VPN devices; while some vendors add the VPN functions into their existing network equipment such as router, access gateway, etc. The functions in the IP-VPN device include security, QoS, and management. The common security functions supported are IPSec (IP Security), IKE (Internet Key Exchange), and Firewall. The QoS functions include bandwidth control and packet scheduling. In the management component, policy-based network management is under standardization in IETF. In this paper, we discuss issues on how to integrate the QoS and security functions in an IP-VPN Gateway. We propose three approaches to do this. They are (1) perform Qos first (2) perform IPSec first and (3) reserve fixed bandwidth for IPSec. We also compare the advantages and disadvantages of the three proposed approaches.

  4. Securing VoIP keeping your VoIP network safe

    CERN Document Server

    (Bud) Bates, Regis J Jr

    2015-01-01

    Securing VoIP: Keeping Your VoIP Network Safe will show you how to take the initiative to prevent hackers from recording and exploiting your company's secrets. Drawing upon years of practical experience and using numerous examples and case studies, technology guru Bud Bates discusses the business realities that necessitate VoIP system security and the threats to VoIP over both wire and wireless networks. He also provides essential guidance on how to conduct system security audits and how to integrate your existing IT security plan with your VoIP system and security plans, helping you prevent

  5. Benefit-Cost Analysis of Integrated Paratransit Systems : Volume 4. Issues in Community Acceptance and IP Implementation.

    Science.gov (United States)

    1979-09-01

    The report describes various factors which influence community acceptance of integrated paratransit (IP) systems. In order to fully explore past events in those communities which have already accepted IP, a case study approach has been used. Seven we...

  6. Truncated power control for improving TCP/IP performance over CDMA wireless links

    DEFF Research Database (Denmark)

    Cianca, Ernestina; Prasad, Ramjee; De Sanctis, Mauro

    2005-01-01

    The issue of the performance degradation of transmission control protocol/Internet Protocol (TCP/IP) over wireless links due to the presence of noncongestion-related packet losses has been addressed with a physical layer approach. The effectiveness of automatic repeat request techniques...... in enhancing TCP/IP performance depends on the tradeoff between frame transmission delay and residual errors after retransmissions. The paper shows how a truncated power control can be effectively applied to improve that tradeoff so that a higher transmission reliability is provided without increasing...... the frame transmission delay through the radio link layer and without increasing the energy consumption. An analytical framework has been developed to show the feasibility and effectiveness of the proposed power control. The analytical results, which are carried out assuming a constant multiuser...

  7. Integrated care for mental health social inclusion through job placement: Implementing IPS in Spain

    OpenAIRE

    Koatz, Débora; Hilarión, Pilar; Bonet, Pere; Suñol, Rosa

    2016-01-01

    Introduction: Individual Placement and Support (IPS) is an integrated social, labor and mental health intervention with an important component of evidence for its effectiveness in helping people with severe mental disorders. Its objective is to obtain and maintain competitive jobs, increase social inclusion and quality of life, and while consuming fewer resources. In Europe, IPS model (which began 14 year ago) is currently implemented in four countries which share background with Dartmouth Co...

  8. Pressurisation of IP-SOFC technology for second generation hybrid application

    Energy Technology Data Exchange (ETDEWEB)

    Jones, L.

    2005-07-01

    The Integrated Planar Solid Oxide Fuel Cell (IP-SOFC) technology developed by Rolls-Royce plc is a hybrid fuel cell technology considered highly suitable for the distributed power generation market. This report presents the results of a project to examine the technical viability of the IP-SOFC technology and some of the associated hybrid system component technologies under pressurised conditions and to investigate the validity of the predicted pressurisation phenomena. The work included: identification of critical material specifications, construction processes, control parameters, etc; the design and commissioning of two pressurised IP-SOFC test rigs at Rolls Royce in Derby; testing two multi-bundle strips at high temperature and atmospheric pressure; testing an active IP-SOFC bundle at high temperature and pressure; testing an experimental steam reforming unit at high temperature and pressure; testing a novel low pressure drop, off-gas combustor concept under atmospheric and pressurised conditions; design studies to identify key parameters affecting the successful integration and packaging of the fuel cell stack with certain associated hybrid components; and designing a hybrid system experimental verification rig. Significant progress was made in addressing the development challenges associated with the IP-SOFC of leakage, performance, durability, yield and geometry, the reaction rate of steam reforming and emissions from the off-gas combustor. Recommendations for future work are made.

  9. Vaccines and IP Rights: A Multifaceted Relationship.

    Science.gov (United States)

    Durell, Karen

    2016-01-01

    Just as there are many forms of vaccines and components to vaccines-particular compositions, delivery systems, components, and distribution networks-there are a variety of intellectual property (IP) protections applicable for vaccines. IP rights such as patent, copyright, trademarks, plant breeders' rights, and trade secrets may all be applicable to vaccines. Thus, discussion of IP rights and vaccines should not begin and end with the application of one IP right to a vaccine. The discussion should engage considerations of multiple IP rights applicable to a vaccine and how these can be utilized in an integrated manner in a strategy aimed at supporting the development and distribution of the vaccine. Such an approach to IP rights to vaccines allows for the integrated rights to be considered in light of the justifications for protecting vaccines with IP rights, as well as the issues relating to specific IP rights for vaccines, such as compulsory license regimes, available humanitarian purpose IP credits, etc. To view vaccines as the subject of multiple IP protections involves a refocusing, but the outcome can provide significant benefits for vaccine development and distribution.

  10. Chromatin immunoprecipitation (ChIP) of plant transcription factors followed by sequencing (ChIP-SEQ) or hybridization to whole genome arrays (ChIP-CHIP)

    NARCIS (Netherlands)

    Kaufmann, K.; Muiño, J.M.; Østerås, M.; Farinelli, L.; Krajewski, P.; Angenent, G.C.

    2010-01-01

    Chromatin immunoprecipitation (ChIP) is a powerful technique to study interactions between transcription factors (TFs) and DNA in vivo. For genome-wide de novo discovery of TF-binding sites, the DNA that is obtained in ChIP experiments needs to be processed for sequence identification. The sequences

  11. Mobility management in mobile IP

    Science.gov (United States)

    Medidi, Sirisha; Golshani, Forouzan

    2002-07-01

    There is an emerging interest in integrating mobile wireless communication with the Internet based on the Ipv6 technology. Many issues introduced by the mobility of users arise when such an integration is attempted. This paper addresses the problem of mobility management, i.e., that of tracking the current IP addresses of mobile terminals and sustaining active IP connections as mobiles move. The paper presents some architectural and mobility management options for integrating wireless access to the Internet. We then present performance results for Mobile IPv4, route optimization and Mobile IPv6.

  12. Challenges Regarding IP Core Functional Reliability

    Science.gov (United States)

    Berg, Melanie D.; LaBel, Kenneth A.

    2017-01-01

    For many years, intellectual property (IP) cores have been incorporated into field programmable gate array (FPGA) and application specific integrated circuit (ASIC) design flows. However, the usage of large complex IP cores were limited within products that required a high level of reliability. This is no longer the case. IP core insertion has become mainstream including their use in highly reliable products. Due to limited visibility and control, challenges exist when using IP cores and subsequently compromise product reliability. We discuss challenges and suggest potential solutions to critical application IP insertion.

  13. Glowbal IP: An Adaptive and Transparent IPv6 Integration in the Internet of Things

    Directory of Open Access Journals (Sweden)

    Antonio J. Jara

    2012-01-01

    Full Text Available The Internet of Things (IoT requires scalability, extensibility and a transparent integration of multi-technology in order to reach an efficient support for global communications, discovery and look-up, as well as access to services and information. To achieve these goals, it is necessary to enable a homogenous and seamless machine-to-machine (M2M communication mechanism allowing global access to devices, sensors and smart objects. In this respect, the proposed answer to these technological requirements is called Glowbal IP, which is based on a homogeneous access to the devices/sensors offered by the IPv6 addressing and core network. Glowbal IP's main advantages with regard to 6LoWPAN/IPv6 are not only that it presents a low overhead to reach a higher performance on a regular basis, but also that it determines the session and identifies global access by means of a session layer defined over the application layer. Technologies without any native support for IP are thereby adaptable to IP e.g. IEEE 802.15.4 and Bluetooth Low Energy. This extension towards the IPv6 network opens access to the features and methods of the devices through a homogenous access based on WebServices (e.g. RESTFul/CoAP. In addition to this, Glowbal IP offers global interoperability among the different devices, and interoperability with external servers and users applications. All in all, it allows the storage of information related to the devices in the network through the extension of the Domain Name System (DNS from the IPv6 core network, by adding the Service Directory extension (DNS-SD to store information about the sensors, their properties and functionality. A step forward in network-based information systems is thereby reached, allowing a homogenous discovery, and access to the devices from the IoT. Thus, the IoT capabilities are exploited by allowing an easier and more transparent integration of the end users applications with sensors for the future evaluations and

  14. Integrative analysis of histone ChIP-seq and transcription data using Bayesian mixture models

    DEFF Research Database (Denmark)

    Klein, Hans-Ulrich; Schäfer, Martin; Porse, Bo T

    2014-01-01

    Histone modifications are a key epigenetic mechanism to activate or repress the transcription of genes. Datasets of matched transcription data and histone modification data obtained by ChIP-seq exist, but methods for integrative analysis of both data types are still rare. Here, we present a novel...

  15. ChIP-PIT: Enhancing the Analysis of ChIP-Seq Data Using Convex-Relaxed Pair-Wise Interaction Tensor Decomposition.

    Science.gov (United States)

    Zhu, Lin; Guo, Wei-Li; Deng, Su-Ping; Huang, De-Shuang

    2016-01-01

    In recent years, thanks to the efforts of individual scientists and research consortiums, a huge amount of chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) experimental data have been accumulated. Instead of investigating them independently, several recent studies have convincingly demonstrated that a wealth of scientific insights can be gained by integrative analysis of these ChIP-seq data. However, when used for the purpose of integrative analysis, a serious drawback of current ChIP-seq technique is that it is still expensive and time-consuming to generate ChIP-seq datasets of high standard. Most researchers are therefore unable to obtain complete ChIP-seq data for several TFs in a wide variety of cell lines, which considerably limits the understanding of transcriptional regulation pattern. In this paper, we propose a novel method called ChIP-PIT to overcome the aforementioned limitation. In ChIP-PIT, ChIP-seq data corresponding to a diverse collection of cell types, TFs and genes are fused together using the three-mode pair-wise interaction tensor (PIT) model, and the prediction of unperformed ChIP-seq experimental results is formulated as a tensor completion problem. Computationally, we propose efficient first-order method based on extensions of coordinate descent method to learn the optimal solution of ChIP-PIT, which makes it particularly suitable for the analysis of massive scale ChIP-seq data. Experimental evaluation the ENCODE data illustrate the usefulness of the proposed model.

  16. Foundations of hardware IP protection

    CERN Document Server

    Torres, Lionel

    2017-01-01

    This book provides a comprehensive and up-to-date guide to the design of security-hardened, hardware intellectual property (IP). Readers will learn how IP can be threatened, as well as protected, by using means such as hardware obfuscation/camouflaging, watermarking, fingerprinting (PUF), functional locking, remote activation, hidden transmission of data, hardware Trojan detection, protection against hardware Trojan, use of secure element, ultra-lightweight cryptography, and digital rights management. This book serves as a single-source reference to design space exploration of hardware security and IP protection. · Provides readers with a comprehensive overview of hardware intellectual property (IP) security, describing threat models and presenting means of protection, from integrated circuit layout to digital rights management of IP; · Enables readers to transpose techniques fundamental to digital rights management (DRM) to the realm of hardware IP security; · Introduce designers to the concept of salutar...

  17. Characterization, Monitoring, and Sensor Technology Integrated Program (CMST-IP)

    International Nuclear Information System (INIS)

    1994-04-01

    The Characterization, Monitoring, and Sensor Technology Integrated Program seeks to deliver needed technologies, timely and cost-effectively, to the Office of Waste Management (EM-30), the Office of Environmental Restoration (EM-40), and the Office of Facility Transition and Management (EM-60). The scope of characterizations monitoring, and sensor technology needs that are required by those organizations encompass: (1) initial location and characterization of wastes and waste environments - prior to treatment; (2) monitoring of waste retrieval, remediation and treatment processes; (3) characterization of the co-position of final waste treatment forms to evaluate the performance of waste treatments processes; and (4) site closure and compliance monitoring. Wherever possible, the CMST-IP fosters technology transfer and commercialization of technologies that it sponsors

  18. IP validation in remote microelectronics testing

    Science.gov (United States)

    Osseiran, Adam; Eshraghian, Kamran; Lachowicz, Stefan; Zhao, Xiaoli; Jeffery, Roger; Robins, Michael

    2004-03-01

    This paper presents the test and validation of FPGA based IP using the concept of remote testing. It demonstrates how a virtual tester environment based on a powerful, networked Integrated Circuit testing facility, aimed to complement the emerging Australian microelectronics based research and development, can be employed to perform the tasks beyond the standard IC test. IC testing in production consists in verifying the tested products and eliminating defective parts. Defects could have a number of different causes, including process defects, process migration and IP design and implementation errors. One of the challenges in semiconductor testing is that while current fault models are used to represent likely faults (stuck-at, delay, etc.) in a global context, they do not account for all possible defects. Research in this field keeps growing but the high cost of ATE is preventing a large community from accessing test and verification equipment to validate innovative IP designs. For these reasons a world class networked IC teletest facility has been established in Australia under the support of the Commonwealth government. The facility is based on a state-of-the-art semiconductor tester operating as a virtual centre spanning Australia and accessible internationally. Through a novel approach the teletest network provides virtual access to the tester on which the DUT has previously been placed. The tester software is then accessible as if the designer is sitting next to the tester. This paper presents the approach used to test and validate FPGA based IPs using this remote test approach.

  19. Exact solution of the p + ip pairing Hamiltonian and a hierarchy of integrable models

    International Nuclear Information System (INIS)

    Dunning, Clare; Ibañez, Miguel; Sierra, Germán; Links, Jon; Zhao, Shao-You

    2010-01-01

    Using the well-known trigonometric six-vertex solution of the Yang–Baxter equation we derive an integrable pairing Hamiltonian with anyonic degrees of freedom. The exact algebraic Bethe ansatz solution is obtained using standard techniques. From this model we obtain several limiting models, including the pairing Hamiltonian with p + ip-wave symmetry. An in-depth study of the p + ip model is then undertaken, including a mean-field analysis, analytical and numerical solutions of the Bethe ansatz equations and an investigation of the topological properties of the ground-state wavefunction. Our main result is that the ground-state phase diagram of the p + ip model consists of three phases. There is the known boundary line with gapless excitations that occurs for vanishing chemical potential, separating the topologically trivial strong pairing phase and the topologically non-trivial weak pairing phase. We argue that a second boundary line exists separating the weak pairing phase from a topologically trivial weak coupling BCS phase, which includes the Fermi sea in the limit of zero coupling. The ground state on this second boundary line is the Moore–Read state

  20. Programmable genetic algorithm IP core for sensing and surveillance applications

    Science.gov (United States)

    Katkoori, Srinivas; Fernando, Pradeep; Sankaran, Hariharan; Stoica, Adrian; Keymeulen, Didier; Zebulum, Ricardo

    2009-05-01

    Real-time evolvable systems are possible with a hardware implementation of Genetic Algorithms (GA). We report the design of an IP core that implements a general purpose GA engine which has been successfully synthesized and verified on a Xilinx Virtex II Pro FPGA Device (XC2VP30). The placed and routed IP core has an area utilization of only 13% and clock speed of 50MHz. The GA core can be customized in terms of the population size, number of generations, cross-over and mutation rates, and the random number generator seed. The GA engine can be tailored to a given application by interfacing with the application specific fitness evaluation module as well as the required storage memory (to store the current and new populations). The core is soft in nature i.e., a gate-level netlist is provided which can be readily integrated with the user's system. The GA IP core can be readily used in FPGA based platforms for space and military applications (for e.g., surveillance, target tracking). The main advantages of the IP core are its programmability, small footprint, and low power consumption. Examples of concept systems in sensing and surveillance domains will be presented.

  1. Mobile telephones: a comparison of radiated power between 3G VoIP calls and 3G VoCS calls.

    Science.gov (United States)

    Jovanovic, Dragan; Bragard, Guillaume; Picard, Dominique; Chauvin, Sébastien

    2015-01-01

    The purpose of this study is to assess the mean RF power radiated by mobile telephones during voice calls in 3G VoIP (Voice over Internet Protocol) using an application well known to mobile Internet users, and to compare it with the mean power radiated during voice calls in 3G VoCS (Voice over Circuit Switch) on a traditional network. Knowing that the specific absorption rate (SAR) is proportional to the mean radiated power, the user's exposure could be clearly identified at the same time. Three 3G (High Speed Packet Access) smartphones from three different manufacturers, all dual-band for GSM (900 MHz, 1800 MHz) and dual-band for UMTS (900 MHz, 1950 MHz), were used between 28 July and 04 August 2011 in Paris (France) to make 220 two-minute calls on a mobile telephone network with national coverage. The places where the calls were made were selected in such a way as to describe the whole range of usage situations of the mobile telephone. The measuring equipment, called "SYRPOM", recorded the radiation power levels and the frequency bands used during the calls with a sampling rate of 20,000 per second. In the framework of this study, the mean normalised power radiated by a telephone in 3G VoIP calls was evaluated at 0.75% maximum power of the smartphone, compared with 0.22% in 3G VoCS calls. The very low average power levels associated with use of 3G devices with VoIP or VoCS support the view that RF exposure resulting from their use is far from exceeding the basic restrictions of current exposure limits in terms of SAR.

  2. Extracellular Matrix-Dependent Generation of Integration- and Xeno-Free iPS Cells Using a Modified mRNA Transfection Method

    Directory of Open Access Journals (Sweden)

    Kang-In Lee

    2016-01-01

    Full Text Available Human induced pluripotent stem cells (iPS cells hold great promise in the field of regenerative medicine, especially immune-compatible cell therapy. The most important safety-related issues that must be resolved before the clinical use of iPS cells include the generation of “footprint-free” and “xeno-free” iPS cells. In this study, we sought to examine whether an extracellular matrix- (ECM- based xeno-free culture system that we recently established could be used together with a microRNA-enhanced mRNA reprogramming method for the generation of clinically safe iPS cells. The notable features of this method are the use of a xeno-free/feeder-free culture system for the generation and expansion of iPS cells rather than the conventional labor-intensive culture systems using human feeder cells or human feeder-conditioned medium and the enhancement of mRNA-mediated reprogramming via the delivery of microRNAs. Strikingly, we observed the early appearance of iPS cell colonies (~11 days, substantial reprogramming efficiency (~0.2–0.3%, and a high percentage of ESC-like colonies among the total colonies (~87.5%, indicating enhanced kinetics and reprogramming efficiency. Therefore, the combined method established in this study provides a valuable platform for the generation and expansion of clinically safe (i.e., integration- and xeno-free iPS cells, facilitating immune-matched cell therapy in the near future.

  3. IP Centrex

    OpenAIRE

    Massa Torrelles, Roger

    2006-01-01

    Este documento recoge el trabajo realizado para diseñar e implementar una centralita o PBX para Telefonía IP basada en VoIP (Voz sobre IP) mediante SIP. Proporcionando una alternativa a las actuales centralitas de telefonía, basadas en hardware, que son caras y poco escalables. Se detallan los conceptos VoIP, IP Centrex, se plantean diferentes esquemas para el diseño de IP Centrex y se presentan los detalles de la implementación de IP Centrex. Para la implementación de IP...

  4. Power Systems Integration Laboratory | Energy Systems Integration Facility

    Science.gov (United States)

    | NREL Power Systems Integration Laboratory Power Systems Integration Laboratory Research in the Energy System Integration Facility's Power Systems Integration Laboratory focuses on the microgrid applications. Photo of engineers testing an inverter in the Power Systems Integration Laboratory

  5. In Silico Pooling of ChIP-seq Control Experiments

    Science.gov (United States)

    Sun, Guannan; Srinivasan, Rajini; Lopez-Anido, Camila; Hung, Holly A.; Svaren, John; Keleş, Sündüz

    2014-01-01

    As next generation sequencing technologies are becoming more economical, large-scale ChIP-seq studies are enabling the investigation of the roles of transcription factor binding and epigenome on phenotypic variation. Studying such variation requires individual level ChIP-seq experiments. Standard designs for ChIP-seq experiments employ a paired control per ChIP-seq sample. Genomic coverage for control experiments is often sacrificed to increase the resources for ChIP samples. However, the quality of ChIP-enriched regions identifiable from a ChIP-seq experiment depends on the quality and the coverage of the control experiments. Insufficient coverage leads to loss of power in detecting enrichment. We investigate the effect of in silico pooling of control samples within multiple biological replicates, multiple treatment conditions, and multiple cell lines and tissues across multiple datasets with varying levels of genomic coverage. Our computational studies suggest guidelines for performing in silico pooling of control experiments. Using vast amounts of ENCODE data, we show that pairwise correlations between control samples originating from multiple biological replicates, treatments, and cell lines/tissues can be grouped into two classes representing whether or not in silico pooling leads to power gain in detecting enrichment between the ChIP and the control samples. Our findings have important implications for multiplexing samples. PMID:25380244

  6. Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence

    OpenAIRE

    Li, Cecilia; Lev, Sophie; Saiardi, Adolfo; Desmarini, Desmarini; Sorrell, Tania C.; Djordjevic, Julianne T.

    2016-01-01

    Fungal inositol polyphosphate (IP) kinases catalyse phosphorylation of IP3 to inositol pyrophosphate, PP-IP5/IP7, which is essential for virulence of Cryptococcus neoformans. Cryptococcal Kcs1 converts IP6 to PP-IP5/IP7, but the kinase converting IP5 to IP6 is unknown. Deletion of a putative IP5 kinase-encoding gene (IPK1) alone (ipk1?), and in combination with KCS1 (ipk1?kcs1?), profoundly reduced virulence in mice. However, deletion of KCS1 and IPK1 had a greater impact on virulence attenua...

  7. Heterogeneous IP Ecosystem enabling Reuse (HIER)

    Science.gov (United States)

    2017-03-22

    HIER project, DARPA also established additional concepts in the formation of the Common Heterogeneous Integration and IP Reuse Strategies (CHIPS...would need a major change to  business model to offer  Hard  or Soft IP – So CHIPS program can be a better fit to these firms • DoD‐Contractor IP pricing

  8. Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells.

    Science.gov (United States)

    Kannappan, Ramaswamy; Mattapally, Saidulu; Wagle, Pooja A; Zhang, Jianyi

    2018-05-18

    The role of p53 transactivation domain (p53-TAD), a multifunctional and dynamic domain, on DNA repair and retaining DNA integrity in human iPS cells has never been studied. p53-TAD was knocked out in iPS cells using CRISPR/Cas9 and was confirmed by DNA sequencing. p53-TAD KO cells were characterized by: accelerated proliferation, decreased population doubling time, and unaltered Bcl2, BBC3, IGF1R, Bax and altered Mdm2, p21, and PIDD transcripts expression. In p53-TAD KO cells p53 regulated DNA repair proteins XPA, DNA polH and DDB2 expression were found to be reduced compared to p53-WT cells. Exposure to low dose of doxorubicin (Doxo) induced similar DNA damage and DNA damage response (DDR) measured by RAD50 and MRE11 expression, Checkpoint kinase 2 activation and γH2A.X recruitment at DNA strand breaks in both the cell groups indicating silencing p53-TAD do not affect DDR mechanism upstream of p53. Following removal of Doxo p53-WT hiPS cells underwent DNA repair, corrected their damaged DNA and restored DNA integrity. Conversely, p53-TAD KO hiPS cells did not undergo complete DNA repair and failed to restore DNA integrity. More importantly continuous culture of p53-TAD KO hiPS cells underwent G2/M cell cycle arrest and expressed cellular senescent marker p16 INK4a . Our data clearly shows that silencing transactivation domain of p53 did not affect DDR but affected the DNA repair process implying the crucial role of p53 transactivation domain in maintaining DNA integrity. Therefore, activating p53-TAD domain using small molecules may promote DNA repair and integrity of cells and prevent senescence.

  9. Legal Protection on IP Cores for System-on-Chip Designs

    Science.gov (United States)

    Kinoshita, Takahiko

    The current semiconductor industry has shifted from vertical integrated model to horizontal specialization model in term of integrated circuit manufacturing. In this circumstance, IP cores as solutions for System-on-Chip (SoC) have become increasingly important for semiconductor business. This paper examines to what extent IP cores of SoC effectively can be protected by current intellectual property system including integrated circuit layout design law, patent law, design law, copyright law and unfair competition prevention act.

  10. Power-Aware Multi-Layer Translucent Network Design: an Integrated OPEX/CAPEX Analysis

    DEFF Research Database (Denmark)

    Saldaña Cercos, Silvia; Resendo, Leandro C.; Ribeiro, Moisés R. N.

    2014-01-01

    We propose a three-phase network design model minimizing CAPEX and OPEX in IP-over-WDM architectures. By forbidding reconfiguration (accounting for 58\\% of the OPEX) we achieve only 4.2\\% increase in power consumption at no CAPEX expenses.......We propose a three-phase network design model minimizing CAPEX and OPEX in IP-over-WDM architectures. By forbidding reconfiguration (accounting for 58\\% of the OPEX) we achieve only 4.2\\% increase in power consumption at no CAPEX expenses....

  11. Protecting LHC IP1/IP5 Components Against Radiation Resulting from Colliding Beam Interactions

    CERN Document Server

    Mokhov, N V; Kerby, J S; Strait, J B

    2003-01-01

    Beam-induced energy deposition in the LHC high luminosity interaction region (IR) components due to both pp collisions and beam loss in the IR vicinity is a significant challenge for the design of the high luminosity insertions. It was shown in our previous studies that a set of absorbers would reduce both the peak power density and total heat load to tolerable levels. In this paper the results of further optimization and comprehensive MARS calculations are summarized for the LHC lattice, version 6.4, for the updated IP1 and IP5 layouts and a baseline pp-collision source term. Power density, power dissipation, particle fluxes and spectra, accumulated dose and residual dose rates are studied in the components of the inner triplets including their TAS absorbers, the TAN neutral beam absorbers, separation dipoles, and quadrupoles of the outer triplets and possible collimators there. Results are given for the nominal luminosity of 1034 cm-2 s-1. The current design is proved to provide the best safety margin under...

  12. Flexoelectric effect in an in-plane switching (IPS) liquid crystal cell for low-power consumption display devices.

    Science.gov (United States)

    Kim, Min Su; Bos, Philip J; Kim, Dong-Woo; Yang, Deng-Ke; Lee, Joong Hee; Lee, Seung Hee

    2016-10-12

    Technology of displaying static images in portable displays, advertising panels and price tags pursues significant reduction in power consumption and in product cost. Driving at a low-frequency electric field in fringe-field switching (FFS) mode can be one of the efficient ways to save powers of the recent portable devices, but a serious drop of image-quality, so-called image-flickering, has been found in terms of the coupling of elastic deformation to not only quadratic dielectric effect but linear flexoelectric effect. Despite of the urgent requirement of solving the issue, understanding of such a phenomenon is yet vague. Here, we thoroughly analyze and firstly report the flexoelectric effect in in-plane switching (IPS) liquid crystal cell. The effect takes place on the area above electrodes due to splay and bend deformations of nematic liquid crystal along oblique electric fields, so that the obvious spatial shift of the optical transmittance is experimentally observed and is clearly demonstrated based on the relation between direction of flexoelectric polarization and electric field polarity. In addition, we report that the IPS mode has inherent characteristics to solve the image-flickering issue in the low-power consumption display in terms of the physical property of liquid crystal material and the electrode structure.

  13. CASSys: an integrated software-system for the interactive analysis of ChIP-seq data

    Directory of Open Access Journals (Sweden)

    Alawi Malik

    2011-06-01

    Full Text Available The mapping of DNA-protein interactions is crucial for a full understanding of transcriptional regulation. Chromatin-immunoprecipitation followed bymassively parallel sequencing (ChIP-seq has become the standard technique for analyzing these interactions on a genome-wide scale. We have developed a software system called CASSys (ChIP-seq data Analysis Software System spanning all steps of ChIP-seq data analysis. It supersedes the laborious application of several single command line tools. CASSys provides functionality ranging from quality assessment and -control of short reads, over the mapping of reads against a reference genome (readmapping and the detection of enriched regions (peakdetection to various follow-up analyses. The latter are accessible via a state-of-the-art web interface and can be performed interactively by the user. The follow-up analyses allow for flexible user defined association of putative interaction sites with genes, visualization of their genomic context with an integrated genome browser, the detection of putative binding motifs, the identification of over-represented Gene Ontology-terms, pathway analysis and the visualization of interaction networks. The system is client-server based, accessible via a web browser and does not require any software installation on the client side. To demonstrate CASSys’s functionality we used the system for the complete data analysis of a publicly available Chip-seq study that investigated the role of the transcription factor estrogen receptor-α in breast cancer cells.

  14. Qualification of Type IP-2, Type IP-3 and Type A packages for radioactive liquid shipments

    International Nuclear Information System (INIS)

    Marcu, L.; Sullivan, G.; Lo, K.K.

    2006-01-01

    Commercial products such as pails, drums or bulk containers can be used for radioactive materials transportation if they can be shown to meet the regulatory requirements. Ontario Power Generation (OPG) has successfully tested and qualified several off-the-shelf containers as Type IP-2, Type IP-3 and Type A packages for liquids in accordance with the International and Canadian Regulations. This paper describes the testing and qualification of these commercial products, and discusses the problems encountered and lessons learned during this process. (author)

  15. Generation of iPS cell lines from schizophrenia patients using a non-integrative method

    Directory of Open Access Journals (Sweden)

    Jaroslaw Sochacki

    2016-07-01

    Full Text Available Skin biopsies were collected from three male patients (age 45, 44 and 44 with clinically diagnosed schizophrenia. The patients were diagnosed according to DSM-5 criteria by a trained psychiatrist. Dermal fibroblast cell lines were established and expanded for subsequent reprogramming procedures. Induced pluripotent stem (iPS cells were derived using the integration-free CytoTune®-iPS 2.0 Sendai Reprogramming Kit, containing Sendai virus particles of the four Yamanaka factors Oct3/4, Sox2, Klf4 and c-Myc.

  16. An ethernet/IP security review with intrusion detection applications

    International Nuclear Information System (INIS)

    Laughter, S. A.; Williams, R. D.

    2006-01-01

    Supervisory Control and Data Acquisition (SCADA) and automation networks, used throughout utility and manufacturing applications, have their own specific set of operational and security requirements when compared to corporate networks. The modern climate of heightened national security and awareness of terrorist threats has made the security of these systems of prime concern. There is a need to understand the vulnerabilities of these systems and how to monitor and protect them. Ethernet/IP is a member of a family of protocols based on the Control and Information Protocol (CIP). Ethernet/IP allows automation systems to be utilized on and integrated with traditional TCP/IP networks, facilitating integration of these networks with corporate systems and even the Internet. A review of the CIP protocol and the additions Ethernet/IP makes to it has been done to reveal the kind of attacks made possible through the protocol. A set of rules for the SNORT Intrusion Detection software is developed based on the results of the security review. These can be used to monitor, and possibly actively protect, a SCADA or automation network that utilizes Ethernet/IP in its infrastructure. (authors)

  17. VoIP Security

    OpenAIRE

    Fontanini, Piero

    2008-01-01

    VOIP or Voice Over Internet Protocol is a common term for phone service over IP based networks. There are much information about VoIP and some of how VoIP can be secured. There is however no standard for VoIP and no general solution for VoIP Security. The security in VoIP systems today are often non existing or in best case weak and often based on proprietary solutions. This master thesis investigates threats to VoIP system and describes existing alternatives for securing Vo...

  18. Security of IP Telephony in Ecuador: Online Analysis

    Directory of Open Access Journals (Sweden)

    José Estrada

    2016-06-01

    Full Text Available Telephony is a global service and thus telephone networks have been a coveted target for criminals. Now that voice can be transported over IP and that multiple services are integrated in a convergent model through Internet, there are more incentives to attack and more attackers. Moreover, the development of open source telephone applications has encouraged the massive use of IP telephony, but not an increased awareness about embedded security risks. Due to the current and intensive adoption of IP telephony systems in Ecuador, we conducted an exploration based on public information to obtain statistics about telephone systems connected to Internet in Ecuador. Additionally, using a deliberately vulnerable IP telephony system, we collected more data to do a preliminary analysis of threats to such systems. We found that hundreds of telephone systems were publicly available on the Internet and using outdated versions of Asterisk-based applications. We also found thousands of malicious interactions on the IP telephony system we deployed on the Internet.

  19. PEMBELAJARAN IPS DALAM REALITA DI ERA KTSP: STUDI EKSPLORASI PELAKSANAAN PEMBELAJARAN IPS PADA JENJANG SMP DI KABUPATEN PATI

    Directory of Open Access Journals (Sweden)

    Edi Sutrisna

    2011-10-01

    Full Text Available Application of KTSP as a curriculum based on competency requires the implementation of strategies and methods that can deliver a number of learners achieving a particular competence. IPS as a subject who has a noble purpose, namely to prepare students to be good citizens, should be taught to students through appropriate strategies and methods by utilizing various media sources and learning. Most social studies teachers still promote the use of expository strategies in presenting lessons of Social Science education and the use of resources and learning media are minimal. Environment, as a laboratory of IPS is not utilized properly.The study shows that most teachers still tend to use expository teaching strategies, use of resources and learning media that are less varied, and integrated approaches to teaching social studies can not be realized by the teachers due to various constraints.   Keywords: learning, IPS, junior school, KTSP   Penerapan KTSP sebagai kurikulum berbasis kompetensi membutuhkan penerapan strategi dan metode yang dapat memberikan sejumlah peserta didik mencapai kompetensi tertentu. IPS sebagai subjek yang memiliki tujuan mulia, yaitu untuk mempersiapkan siswa untuk menjadi warga negara yang baik, harus diajarkan kepada siswa melalui strategi yang tepat dan metode dengan memanfaatkan berbagai sumber media dan pembelajaran. Kebanyakan guru IPS masih menggunakan strategi ekspositori dalam menyajikan meteri pelajaran IPS dengan menggunakan sumber daya dan media pembelajaran yang minimal. Lingkungan sekitar, sebagai laboratorium IPS tidak digunakan menunjukkan pembelajaran yang baik. Kebanyakan guru masih cenderung untuk menggunakan strategi pengajaran ekspositori, penggunaan sumber daya dan media pembelajaran yang kurang bervariasi, dan pendekatan terpadu untuk mengajar IPS, sehingga tidak dapat direalisasikan oleh para guru karena berbagai kendala.   Kata kunci: pembelajaran, IPS, SMP, KTSP  

  20. Grid Integration | Water Power | NREL

    Science.gov (United States)

    Grid Integration Grid Integration For marine and hydrokinetic technologies to play a larger role in supplying the nation's energy needs, integration into the U.S. power grid is an important challenge to address. Efficient integration of variable power resources like water power is a critical part of the

  1. Impact of artefact removal on ChIP quality metrics in ChIP-seq and ChIP-exo data.

    Directory of Open Access Journals (Sweden)

    Thomas Samuel Carroll

    2014-04-01

    Full Text Available With the advent of ChIP-seq multiplexing technologies and the subsequent increase in ChIP-seq throughput, the development of working standards for the quality assessment of ChIP-seq studies has received significant attention. The ENCODE consortium’s large scale analysis of transcription factor binding and epigenetic marks as well as concordant work on ChIP-seq by other laboratories has established a new generation of ChIP-seq quality control measures. The use of these metrics alongside common processing steps has however not been evaluated. In this study, we investigate the effects of blacklisting and removal of duplicated reads on established metrics of ChIP-seq quality and show that the interpretation of these metrics is highly dependent on the ChIP-seq preprocessing steps applied. Further to this we perform the first investigation of the use of these metrics for ChIP-exo data and make recommendations for the adaptation of the NSC statistic to allow for the assessment of ChIP-exo efficiency.

  2. ReMap 2018: an updated atlas of regulatory regions from an integrative analysis of DNA-binding ChIP-seq experiments.

    Science.gov (United States)

    Chèneby, Jeanne; Gheorghe, Marius; Artufel, Marie; Mathelier, Anthony; Ballester, Benoit

    2018-01-04

    With this latest release of ReMap (http://remap.cisreg.eu), we present a unique collection of regulatory regions in human, as a result of a large-scale integrative analysis of ChIP-seq experiments for hundreds of transcriptional regulators (TRs) such as transcription factors, transcriptional co-activators and chromatin regulators. In 2015, we introduced the ReMap database to capture the genome regulatory space by integrating public ChIP-seq datasets, covering 237 TRs across 13 million (M) peaks. In this release, we have extended this catalog to constitute a unique collection of regulatory regions. Specifically, we have collected, analyzed and retained after quality control a total of 2829 ChIP-seq datasets available from public sources, covering a total of 485 TRs with a catalog of 80M peaks. Additionally, the updated database includes new search features for TR names as well as aliases, including cell line names and the ability to navigate the data directly within genome browsers via public track hubs. Finally, full access to this catalog is available online together with a TR binding enrichment analysis tool. ReMap 2018 provides a significant update of the ReMap database, providing an in depth view of the complexity of the regulatory landscape in human. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  3. Intelligent Advanced Communications IP Telephony Feasibility for the U.S. Navy (DVD)

    National Research Council Canada - National Science Library

    Binns, Todd D; Naas, Bill

    2007-01-01

    ...: 2 DVD-ROMs; 4 3/4 in.; 2.68 GB. ABSTRACT: The purpose of this research paper is to research technologies and solutions supporting the communications infrastructure necessary to implement an integrated VoIP (IP telephony...

  4. An Installation of IPS Bypass Line at the Fuel Test Loop

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Ho Young; Ahn, G. H.; Lee, M.; Kim, M. S.; Cho, S. H.; Han, J. S.; Hur, S. O. [KAERI, Daejeon (Korea, Republic of)

    2010-12-15

    The Fuel Test Loop(FTL) was installed for the national goal of self-supporting technology in the field of design and construction of nuclear power plant. The FTL with the fuel irradiation equipment is essential in developing, improving and inspecting the fuel of CANDU type or PWR type nuclear power plant. The FTL should be operated at the same conditions of commercial nuclear power plant such as temperature, pressure, flow rate, neutron flux and so on. Starting designing in December 2001, the FTL was installed from March 2007 to August 2008. Especially the In Pile Section(IPS) was installed at IR1 hole in August 2008. Until September 2009 after loading the test fuel, a series of power escalation tests (LSD, CSB1, CSB2, HSB, HOP) were conducted. And it was operated at the condition of CSB2 for the 8 cycles from October 2009 to July 2010. But it could not be normally operated in early 2010, because the high radiation released from irradiated materials due to the worn down bearing of main cooling pump. So, we removed the IPS and installed a newly designed IPS bypass line to prevent increasing high radiation. In this report we will present preliminary works, main works processes, devices of making work environments, a designing and manufacturing of IPS bypass line and a rack of IPS, installing know-hows, problems and solutions broke out during the work etc. We believe that our efforts to complete successful installing and operating of the FTL system will contribute for the efficient utilization of HANARO

  5. Salt Lake City Area Integrated Projects Electric Power Marketing. Draft environmental impact statement: Volume 3, Appendix A

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    The Salt Lake City Area Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Green, Gunnison, Rio Grande, and Colorado rivers and on Deer and Plateau creeks in the states of Wyoming, Utah, Colorado, Arizona, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams;) are influenced by Western power scheduling and transmission decisions. The EIS alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Westerns firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this environmental impact statement (EIS) include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources.

  6. A survey of IP over ATM architectures

    Energy Technology Data Exchange (ETDEWEB)

    Chen, H.; Tsang, R.; Brandt, J.; Hutchins, J.

    1997-07-01

    Over the past decade, the Internet has burgeoned into a worldwide information highway consisting of approximately 5 million hosts on over 45,000 interconnected networks. This unprecedented growth, together with the introduction of multimedia workstations, has spurred the development of innovative applications that require high speed, low latency, and real-time transport. Today`s Internet can neither scale in its bandwidth nor guarantee the Quality of Services (QoS) necessary to meet these performance requirements. Many network researchers propose to use the Asynchronous Transfer Mode (ATM) technology as the underlying infrastructure for the next generation of workgroup, campus, and enterprise IP networks. Since ATM is significantly different from today`s legacy network technologies, efficient implementation of IP over ATM is especially challenging. This tutorial paper covers several existing proposals that integrate IP over ATM.

  7. PERFORMANCE EVALUATION OF INTEGRATED MACRO AND MICRO MOBILITY PROTOCOLS FOR WIDE AREA WIRELESS NETWORKS

    Directory of Open Access Journals (Sweden)

    R.Gunasundari

    2010-03-01

    Full Text Available The success of next generation wireless networks will rely much on advanced mechanisms for seamless mobility support among emerging heterogeneous technologies. Currently, Mobile IP is the most promising solution for mobility management in the Internet. Several IP micro mobility approaches have been proposed to enhance the performance of Mobile IP which supports quality of service, minimum packet loss, limited handoff delay and scalability and power conservation but they are not scalable for macro mobility. A practical solution would therefore require integration of Mobile IP and Micro mobility protocols where Mobile IP handles macro mobility and micro mobility protocols handles micro mobility. In this paper an integrated mobility management protocol for IP based wireless networks is proposed and analyzed. Simulation results presented in this paper are based on ns 2.

  8. Salt Lake City Area Integrated Projects electric power marketing -- Final environmental impact statement. Volume 1: Summary

    International Nuclear Information System (INIS)

    1996-01-01

    The Colorado River Storage Project Customer Service Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Colorado, Green, Gunnison, and Rio Grande rivers and on Plateau Creek in Arizona, Colorado, Utah, Wyoming, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams) are influenced by Western power scheduling and transmission decisions. The environmental impact statement (EIS) alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Western's firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this EIS include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources. Western has identified commitment-level alternative 1, the Post-1989 commitment level, as its preferred alternative. The impact evaluations indicate that this commitment level is also the environmentally preferred alternative

  9. PENGGUNAAN METODE SIMULASI DALAM PEMBELAJARAN KETERAMPILAN LITERASI INFORMASI IPS BAGI MAHASISWA PGSD

    Directory of Open Access Journals (Sweden)

    Ana Nurhasanah

    2016-06-01

    Full Text Available Abstrak. Mata pelajaran IPS di Sekolah Dasar dikembangkan sebagai mata pelajaran terintegrasi atau integrative social studies, bukan sebagai pendidikan disiplin ilmu. Tantangan yang dihadapi peserta didik saat ini adalah banyak dan beragamnya masalah-masalah sosial yang harus dihadapi dalam kehidupan sehari-hari, oleh sebab itu pembelajaran IPS bertujuan untuk  mengembangkan keterampilan sosial. Namun, mengingat perkembangan siswa SD yang masih dalam tingkat berpikir kongkrit maka disarankan pembelajaran IPS SD menggunakan contoh-contoh masalah sosial yang kongkrit dan yang  mungkin melibatkan pengalaman-pengalaman siswa SD secara langsung. Namun dalam kenyataannya berdasarkan wawancara pada guru-guru SD di kota Serang masih banyak ditemukan kesulitan dalam mengajarkan IPS. Hal ini menunjukan bahwa kemampuan guru-guru di SD belum sesuai dengan tuntutan tujuan pembelajaran IPS. Oleh sebab itu penting kiranya mahasiswa PGSD semester V sebagai calon tenaga pendidik dibekali pengalaman dengan metode simulasi guna mengembangkan literasi informasi pada pembelajaran IPS yang menunjang pada pengembangan karir profesionalnya nanti. Kata kunci: metode simulasi, literasi informasi IPS, dan mahasiswa  Abstract. Social studies in elementary school subjects developed as an integrated or integrative social studies, not as educational disciplines. The challenges facing students today are many and varied social problems that must be faced in everyday life, so learning IPS aims to develop social skills. However, considering the development of elementary school students who are still in the level of concrete thinking it is advisable elementary social studies learning using examples of concrete social problems and that may involve experiences elementary students directly. But in reality based on the interviews of the teachers in the city of Serang there are still many difficulties in teaching social studies. This shows that the ability of teachers in primary

  10. CMOS integrated switching power converters

    CERN Document Server

    Villar-Pique, Gerard

    2011-01-01

    This book describes the structured design and optimization of efficient, energy processing integrated circuits. The approach is multidisciplinary, covering the monolithic integration of IC design techniques, power electronics and control theory. In particular, this book enables readers to conceive, synthesize, design and implement integrated circuits with high-density high-efficiency on-chip switching power regulators. Topics covered encompass the structured design of the on-chip power supply, efficiency optimization, IC-compatible power inductors and capacitors, power MOSFET switches and effi

  11. LMIP/AAA: Local Authentication, Authorization and Accounting (AAA) Protocol for Mobile IP

    Science.gov (United States)

    Chenait, Manel

    Mobile IP represents a simple and scalable global mobility solution. However, it inhibits various vulnerabilities to malicious attacks and, therefore, requires the integration of appropriate security services. In this paper, we discuss two authentication schemes suggested for Mobile IP: standard authentication and Mobile IP/AAA authentication. In order to provide Mobile IP roaming services including identity verication, we propose an improvement to Mobile/AAA authentication scheme by applying a local politic key management in each domain, hence we reduce hando latency by avoiding the involvement of AAA infrastructure during mobile node roaming.

  12. Smart Grid Applications for a Practical Implementation of IP over Narrowband Power Line Communications

    Directory of Open Access Journals (Sweden)

    Noelia Uribe-Pérez

    2017-11-01

    Full Text Available Currently, Advanced Metering Infrastructure (AMI systems have equipped the low voltage section with a communication system that is being used mainly for metering purposes, but it can be further employed for additional applications related to the Smart Grid (SG concept. This paper explores the potential applications beyond metering of the available channel in a Power Line Communication-based AMI system. To that end, IP has been implemented over Narrow Band-Power Line Communication (NB-PLC in a real microgrid, which includes an AMI system. A thorough review of potential applications for the SG that might be implemented for this representative case is included in order to provide a realistic analysis of the potentiality of NB-PLC beyond smart metering. The results demonstrate that existing AMI systems based on NB-PLC have the capacity to implement additional applications such as remote commands or status signals, which entails an added value for deployed AMI systems.

  13. Localitzador Gràfic de Direccions IP 'IpLocInspector'

    OpenAIRE

    Ordóñez Chapado, Miguel

    2006-01-01

    En aquest treball s'ha desenvolupat una aplicació capaç de localitzar adreces IP. En este trabajo se ha desarrollado una aplicación capaz de localizar direcciones IP. In this work an application was developed capable of locating IP addresses.

  14. Feasibility Study of VoIP Integration into the MYSEA Environment

    National Research Council Canada - National Science Library

    Tse, Lily

    2005-01-01

    .... VoIP is widely implemented with H.323 and Session Initiation Protocol (SIP) standards. However, both protocols are poorly designed for networks with common security solutions such as firewalls and Network Address Translation...

  15. Salt Lake City Area Integrated Projects Electric Power Marketing. Draft environmental impact statement: Volume 4, Appendixes B-D

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    The Salt Lake City Area Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Green, Gunnison, Rio Grande, and Colorado rivers and on Deer and Plateau creeks in the states of Wyoming, Utah, Colorado, Arizona, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams;) are influenced by Western power scheduling and transmission decisions. The EIS alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Westerns firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this environmental impact statement (EIS) include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources.

  16. Salt Lake City Area Integrated Projects Electric Power Marketing. Draft environmental impact statement: Volume 2, Sections 1-16

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    The Salt Lake City Area Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Green, Gunnison, Rio Grande, and Colorado rivers and on Deer and Plateau creeks in the states of Wyoming, Utah, Colorado, Arizona, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams;) are influenced by Western power scheduling and transmission decisions. The EIS alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Westerns firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this environmental impact statement (EIS) include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources.

  17. SEMICONDUCTOR INTEGRATED CIRCUITS A 10-bit 200-kS/s SAR ADC IP core for a touch screen SoC

    Science.gov (United States)

    Xingyuan, Tong; Yintang, Yang; Zhangming, Zhu; Wenfang, Sheng

    2010-10-01

    Based on a 5 MSBs (most-significant-bits)-plus-5 LSBs (least-significant-bits) C-R hybrid D/A conversion and low-offset pseudo-differential comparison approach, with capacitor array axially symmetric layout topology and resistor string low gradient mismatch placement method, an 8-channel 10-bit 200-kS/s SAR ADC (successive-approximation-register analog-to-digital converter) IP core for a touch screen SoC (system-on-chip) is implemented in a 0.18 μm 1P5M CMOS logic process. Design considerations for the touch screen SAR ADC are included. With a 1.8 V power supply, the DNL (differential non-linearity) and INL (integral non-linearity) of this converter are measured to be about 0.32 LSB and 0.81 LSB respectively. With an input frequency of 91 kHz at 200-kS/s sampling rate, the spurious-free dynamic range and effective-number-of-bits are measured to be 63.2 dB and 9.15 bits respectively, and the power is about 136 μW. This converter occupies an area of about 0.08 mm2. The design results show that it is very suitable for touch screen SoC applications.

  18. Evaluation of VoIP QoS Performance in Wireless Mesh Networks

    Directory of Open Access Journals (Sweden)

    Mohammad Tariq Meeran

    2017-07-01

    Full Text Available The main focus of this research article is the evaluation of selected voice over Internet protocol (VoIP solutions in wireless mesh network (WMN scenarios. While WMNs have self-healing, self-forming, and dynamic topology features, they still pose challenges for the implementation of multimedia applications such as voice in various scenarios. Therefore, various solutions to make WMN more suitable for VoIP application have been proposed in the scientific literature. In this work, we have extensively explored a set of applicable scenarios by conducting experiments by means of a network simulator. The following scenarios were selected as the most representatives for performance evaluation: first responders, flooded village, remote village, and platoon deployment. Each selected scenario has been studied under six sub-scenarios corresponding to various combinations of the IEEE 802.11g, 802.11n, 802.11s, and 802.11e standards; the G.711 and G.729 codecs; and the ad hoc on demand distance vector (AODV and hybrid wireless mesh protocol (HWMP routing protocols. The results in terms of quality of service (measured with the mean opinion score rating scale, supported by the analysis of delay, jitter and packet loss, show that 802.11g integration with both VoIP codecs and AODV routing protocol results in better VoIP performance as compared to most other scenarios. In case of 802.11g integration with 802.11s, VoIP performance decreases as compared to the other sub-scenarios without 802.11s. The results also show that 802.11n integration with 802.11e decreases VoIP performance in larger deployments. We conclude the paper with some recommendations in terms of combinations of those standards and protocols with a view to achieve a higher quality of service for the given scenarios.

  19. Salt Lake City Utah Integrated Projects electric power marketing. Final environmental impact statement, Volume 5: Appendix E

    International Nuclear Information System (INIS)

    1996-01-01

    The Colorado River Storage Project Customer Service Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Colorado, Green, Gunnison, and Rio Grande rivers and on Plateau Creek in Arizona, Colorado, Utah, Wyoming, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams) are influenced by Western power scheduling and transmission decisions. The environmental impact statement (EIS) alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Western's firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this EIS include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources. Western has identified commitment-level alternative 1, the Post-1989 commitment level, as its preferred alternative. The impact evaluations indicate that this commitment level is also the environmentally preferred alternative

  20. An IP-10 (CXCL10)-Derived Peptide Inhibits Angiogenesis

    Science.gov (United States)

    Yates-Binder, Cecelia C.; Rodgers, Margaret; Jaynes, Jesse; Wells, Alan; Bodnar, Richard J.; Turner, Timothy

    2012-01-01

    Angiogenesis plays a critical role in processes such as organ development, wound healing, and tumor growth. It requires well-orchestrated integration of soluble and matrix factors and timely recognition of such signals to regulate this process. Previous work has shown that newly forming vessels express the chemokine receptor CXC receptor 3 (CXCR3) and, activation by its ligand IP-10 (CXCL10), both inhibits development of new vasculature and causes regression of newly formed vessels. To identify and develop new therapeutic agents to limit or reverse pathological angiogenesis, we identified a 21 amino acid fragment of IP-10, spanning the α-helical domain residues 77–98, that mimic the actions of the whole IP-10 molecule on endothelial cells. Treatment of the endothelial cells with the 22 amino acid fragment referred to as IP-10p significantly inhibited VEGF-induced endothelial motility and tube formation in vitro, properties critical for angiogenesis. Using a Matrigel plug assay in vivo, we demonstrate that IP-10p both prevented vessel formation and induced involution of nascent vessels. CXCR3 neutralizing antibody was able to block the inhibitory effects of the IP-10p, demonstrating specificity of the peptide. Inhibition of endothelial function by IP-10p was similar to that described for IP-10, secondary to CXCR3-mediated increase in cAMP production, activation of PKA inhibiting cell migration, and inhibition of VEGF-mediated m-calpain activation. IP-10p provides a novel therapeutic agent that inhibits endothelial cell function thus, allowing for the modulation of angiogenesis. PMID:22815829

  1. An integrated model of multiple-condition ChIP-Seq data reveals predeterminants of Cdx2 binding.

    Directory of Open Access Journals (Sweden)

    Shaun Mahony

    2014-03-01

    Full Text Available Regulatory proteins can bind to different sets of genomic targets in various cell types or conditions. To reliably characterize such condition-specific regulatory binding we introduce MultiGPS, an integrated machine learning approach for the analysis of multiple related ChIP-seq experiments. MultiGPS is based on a generalized Expectation Maximization framework that shares information across multiple experiments for binding event discovery. We demonstrate that our framework enables the simultaneous modeling of sparse condition-specific binding changes, sequence dependence, and replicate-specific noise sources. MultiGPS encourages consistency in reported binding event locations across multiple-condition ChIP-seq datasets and provides accurate estimation of ChIP enrichment levels at each event. MultiGPS's multi-experiment modeling approach thus provides a reliable platform for detecting differential binding enrichment across experimental conditions. We demonstrate the advantages of MultiGPS with an analysis of Cdx2 binding in three distinct developmental contexts. By accurately characterizing condition-specific Cdx2 binding, MultiGPS enables novel insight into the mechanistic basis of Cdx2 site selectivity. Specifically, the condition-specific Cdx2 sites characterized by MultiGPS are highly associated with pre-existing genomic context, suggesting that such sites are pre-determined by cell-specific regulatory architecture. However, MultiGPS-defined condition-independent sites are not predicted by pre-existing regulatory signals, suggesting that Cdx2 can bind to a subset of locations regardless of genomic environment. A summary of this paper appears in the proceedings of the RECOMB 2014 conference, April 2-5.

  2. Diseño del Sistema Integral de Medicion de Gestion (SIMEG de la IPS del Instituto de Seguros Sociales

    Directory of Open Access Journals (Sweden)

    Paula Bernal Gelvis

    2000-12-01

    Full Text Available Este articulo presenta los resultados obtenidos en la monografia "Diserio del Sistema Integral de Medici6n de la Gestión (SIMEG en la Institución prestadora de servicios (IPS del Instituto de Seguros Sociales (ISS"; en la que -utilizando la inferencia deductiva-, se plantea el SIMEG como una herramienta administrativa para la evaluación y el monitoreo de la gestión. Para el diseño de esta herramienta, en primera instancia se realiza un acercamiento teórico a la metodología recurriendo a diversas fuentes bibliográficas (Iibros, artículos, publicaciones en Internet, panelistas, seminarios, etc. para determinar el estado del arte del Balanced Scorecard y las metodologías analoqas tales como el SIMEG; y en segundo lugar, se construye un marco conceptual sobre el objeto de estudio, la Institución prestadora de servicios (IPS del ISS, a través del establecimiento del marco legal, el análisis situacional y la recolección de información interna (administrativa, estratégica. presupuestal, financiera, contable, estadistica, etc.. De esta manera se logra una aproximaci6n te6rica al Sistema integral de medición de la gestión, SIMEG, que proporcione las herramientas necesarias para comprender la magnitud y el alcance de la metodología que se pretende implementar. Finalmente se describe paso a paso el proceso metodológico utilizado en su implantación en la IPS del ISS y, por ultimo, se plantean sugerencias con el objeto de asegurar el éxito en dicho proceso.

  3. Computational Methods for ChIP-seq Data Analysis and Applications

    KAUST Repository

    Ashoor, Haitham

    2017-04-25

    The development of Chromatin immunoprecipitation followed by sequencing (ChIP-seq) technology has enabled the construction of genome-wide maps of protein-DNA interaction. Such maps provide information about transcriptional regulation at the epigenetic level (histone modifications and histone variants) and at the level of transcription factor (TF) activity. This dissertation presents novel computational methods for ChIP-seq data analysis and applications. The work of this dissertation addresses four main challenges. First, I address the problem of detecting histone modifications from ChIP-seq cancer samples. The presence of copy number variations (CNVs) in cancer samples results in statistical biases that lead to inaccurate predictions when standard methods are used. To overcome this issue I developed HMCan, a specially designed algorithm to handle ChIP-seq cancer data by accounting for the presence of CNVs. When using ChIP-seq data from cancer cells, HMCan demonstrates unbiased and accurate predictions compared to the standard state of the art methods. Second, I address the problem of identifying changes in histone modifications between two ChIP-seq samples with different genetic backgrounds (for example cancer vs. normal). In addition to CNVs, different antibody efficiency between samples and presence of samples replicates are challenges for this problem. To overcome these issues, I developed the HMCan-diff algorithm as an extension to HMCan. HMCan-diff implements robust normalization methods to address the challenges listed above. HMCan-diff significantly outperforms another state of the art methods on data containing cancer samples. Third, I investigate and analyze predictions of different methods for enhancer prediction based on ChIP-seq data. The analysis shows that predictions generated by different methods are poorly overlapping. To overcome this issue, I developed DENdb, a database that integrates enhancer predictions from different methods. DENdb also

  4. Voice Over Internet Protocol (VoIP) in a Control Center Environment

    Science.gov (United States)

    Pirani, Joseph; Calvelage, Steven

    2010-01-01

    The technology of transmitting voice over data networks has been available for over 10 years. Mass market VoIP services for consumers to make and receive standard telephone calls over broadband Internet networks have grown in the last 5 years. While operational costs are less with VoIP implementations as opposed to time division multiplexing (TDM) based voice switches, is it still advantageous to convert a mission control center s voice system to this newer technology? Marshall Space Flight Center (MSFC) Huntsville Operations Support Center (HOSC) has converted its mission voice services to a commercial product that utilizes VoIP technology. Results from this testing, design, and installation have shown unique considerations that must be addressed before user operations. There are many factors to consider for a control center voice design. Technology advantages and disadvantages were investigated as they refer to cost. There were integration concerns which could lead to complex failure scenarios but simpler integration for the mission infrastructure. MSFC HOSC will benefit from this voice conversion with less product replacement cost, less operations cost and a more integrated mission services environment.

  5. On the implementation of IP protection using biometrics based information hiding and firewall

    Science.gov (United States)

    Basu, Abhishek; Nandy, Kingshuk; Banerjee, Avishek; Giri, Supratick; Sarkar, Souvik; Sarkar, Subir Kumar

    2016-02-01

    System-on-chip-based design style creates a revolution in very large scale integration industry with design efficiency, operating speed and development time. To support this process, reuse and exchange of components are essential in electronic form called intellectual property (IP). This, however, increases the possibility of encroachment of IP of the design. So copyright protection of IP against piracy is the most important concern for IP vendors. The existing solutions for IP protection are still not secure enough with flexibility, cost, etc. This paper proposes an information-hiding-based solution for IP protection by embedding a biometric copyright information and firewall inside an IP in the form of a finite state machine with unique configuration. The scheme first introduces biometric signature-based copyright as ownership proof. Second, firewall interrupts the normal functionality of IP at the end of the user time period. The experimental outcomes of field-programmable-gate-array implementation illustrate the efficiency of the proposed method.

  6. Experimental evaluation of the IP multimedia subsystem

    NARCIS (Netherlands)

    Oredope, A.; Liotta, A.; Yang, K.; Tyrode-Goilo, D.H.; Magedanz, T.; Mauro Madeira, E.R.M.; Dini, P.

    2005-01-01

    The IP Multimedia Subsystem (IMS) is the latest framework for a seamless conversion of the ordinary Internet with mobile cellular systems. As such it has the backing of all major companies since it aims to offer a unified solution to integrated mobile services, including mechanisms for security,

  7. Multiformat decoder for a DSP-based IP set-top box

    Science.gov (United States)

    Pescador, F.; Garrido, M. J.; Sanz, C.; Juárez, E.; Samper, D.; Antoniello, R.

    2007-05-01

    Internet Protocol Set-Top Boxes (IP STBs) based on single-processor architectures have been recently introduced in the market. In this paper, the implementation of an MPEG-4 SP/ASP video decoder for a multi-format IP STB based on a TMS320DM641 DSP is presented. An initial decoder for PC platform was fully tested and ported to the DSP. Using this code an optimization process was started achieving a 90% speedup. This process allows real-time MPEG-4 SP/ASP decoding. The MPEG-4 decoder has been integrated in an IP STB and tested in a real environment using DVD movies and TV channels with excellent results.

  8. Salt Lake City Area Integrated Projects electric power marketing final environmental impact statement. Volume 4: Appendixes B-D

    International Nuclear Information System (INIS)

    1996-01-01

    The Colorado River Storage Project Customer Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Colorado, Green, Gunnison, and Rio Grande rivers and on Plateau Creek in Arizona, Colorado, Utah, Wyoming, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams) are influenced by Western power scheduling and transmission decisions. The environmental impact statement (EIS) alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Western's firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this EIS include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources. Western has identified commitment-level alternative 1, the Post-1989 commitment level, as its preferred alternative. The impact evaluations indicate that this commitment level is also the environmentally preferred alter native

  9. Salt Lake City Area Integrated Projects electric power marketing -- Final environmental impact statement. Volume 2: Sections 1--16

    International Nuclear Information System (INIS)

    1996-01-01

    The Colorado River Storage Project Customer Service Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Colorado, Green, Gunnison, and Rio Grande rivers and on Plateau Creek in Arizona, Colorado, Utah, Wyoming, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams) are influenced by Western power scheduling and transmission decisions. The environmental impact statement (EIS) alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Western's firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this EIS include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources. Western has identified commitment-level alternative 1, the Post-1989 commitment level, as its preferred alternative. The impact evaluations indicate that this commitment level is also the environmentally preferred alternative

  10. The psisub(IPS)-LAS relation for extragalactic radio sources

    International Nuclear Information System (INIS)

    Banhatti, D.G.

    1984-01-01

    Metre-wavelength interplanetary scintillation (IPS) observations give the overall angular sizes psi of scintillating compact structures in radio sources. From 326.5-MHz IPS data for a sample of faint (Ooty) radio sources, log psi versus log (largest angular size) is seen, on average, to have a slope 0.2, significantly less than one. A similar trend is seen from 81.5-MHz IPS data for a sample of strong, powerful (3CR) double sources, although the slope is 0.4 and the mean psi about four times larger. The difference in slopes is due mainly to the large spread in the redshifts of the 3CR sources compared to the expected narrow range for the Ooty sources, while the difference in mean psi values is due to the different methods of determining psi for the two samples, the different frequencies used for the IPS observations and the different mean LAS values. (author)

  11. Evaluation of IP Portfolios

    DEFF Research Database (Denmark)

    Søberg, Peder Veng

    2009-01-01

    As a result of an inquiry concerning how to evaluate IP (intellectual property) portfolios in order to enable the best possible use of IP resources within organizations, an IP evaluation approach primarily applicable for patents and utility models is developed. The developed approach is useful...... of the organization owning the IP....

  12. RIDES: Robust Intrusion Detection System for IP-Based Ubiquitous Sensor Networks.

    Science.gov (United States)

    Amin, Syed Obaid; Siddiqui, Muhammad Shoaib; Hong, Choong Seon; Lee, Sungwon

    2009-01-01

    The IP-based Ubiquitous Sensor Network (IP-USN) is an effort to build the "Internet of things". By utilizing IP for low power networks, we can benefit from existing well established tools and technologies of IP networks. Along with many other unresolved issues, securing IP-USN is of great concern for researchers so that future market satisfaction and demands can be met. Without proper security measures, both reactive and proactive, it is hard to envisage an IP-USN realm. In this paper we present a design of an IDS (Intrusion Detection System) called RIDES (Robust Intrusion DEtection System) for IP-USN. RIDES is a hybrid intrusion detection system, which incorporates both Signature and Anomaly based intrusion detection components. For signature based intrusion detection this paper only discusses the implementation of distributed pattern matching algorithm with the help of signature-code, a dynamically created attack-signature identifier. Other aspects, such as creation of rules are not discussed. On the other hand, for anomaly based detection we propose a scoring classifier based on the SPC (Statistical Process Control) technique called CUSUM charts. We also investigate the settings and their effects on the performance of related parameters for both of the components.

  13. PVM and IP multicast

    Energy Technology Data Exchange (ETDEWEB)

    Dunigan, T.H.; Hall, K.A.

    1996-12-01

    This report describes a 1994 demonstration implementation of PVM that uses IP multicast. PVM`s one-to-many unicast implementation of its pvm{_}mcast() function is replaced with reliable IP multicast. Performance of PVM using IP multicast over local and wide-area networks is measured and compared with the original unicast implementation. Current limitations of IP multicast are noted.

  14. Effective Domain Partitioning for Multi-Clock Domain IP Core Wrapper Design under Power Constraints

    Science.gov (United States)

    Yu, Thomas Edison; Yoneda, Tomokazu; Zhao, Danella; Fujiwara, Hideo

    The rapid advancement of VLSI technology has made it possible for chip designers and manufacturers to embed the components of a whole system onto a single chip, called System-on-Chip or SoC. SoCs make use of pre-designed modules, called IP-cores, which provide faster design time and quicker time-to-market. Furthermore, SoCs that operate at multiple clock domains and very low power requirements are being utilized in the latest communications, networking and signal processing devices. As a result, the testing of SoCs and multi-clock domain embedded cores under power constraints has been rapidly gaining importance. In this research, a novel method for designing power-aware test wrappers for embedded cores with multiple clock domains is presented. By effectively partitioning the various clock domains, we are able to increase the solution space of possible test schedules for the core. Since previous methods were limited to concurrently testing all the clock domains, we effectively remove this limitation by making use of bandwidth conversion, multiple shift frequencies and properly gating the clock signals to control the shift activity of various core logic elements. The combination of the above techniques gains us greater flexibility when determining an optimal test schedule under very tight power constraints. Furthermore, since it is computationally intensive to search the entire expanded solution space for the possible test schedules, we propose a heuristic 3-D bin packing algorithm to determine the optimal wrapper architecture and test schedule while minimizing the test time under power and bandwidth constraints.

  15. Using VoIP to compete.

    Science.gov (United States)

    Werbach, Kevin

    2005-09-01

    Internet telephony, or VoIP, is rapidly replacing the conventional kind. This year, for the first time, U.S. companies bought more new Internet-phone connections than standard lines. The major driver behind this change is cost. But VoIP isn't just a new technology for making old-fashioned calls cheaper, says consultant Kevin Werbach. It is fundamentally changing how companies use voice communications. What makes VoIP so powerful is that it turns voice into digital data packets that can be stored, copied, combined with other data, and distributed to virtually any device that connects to the Internet. And it makes it simple to provide all the functionality of a corporate phone-call features, directories, security-to anyone anywhere there's broadband access. That fosters new kinds of businesses such as virtual call centers, where widely dispersed agents work at all hours from their homes. The most successful early adopters, says Werbach, will focus more on achieving business objectives than on saving money. They will also consider how to push VoIP capabilities out to the extended organization, making use of everyone as a resource. Deployment may be incremental, but companies should be thinking about where VoIP could take them. Executives should ask what they could do if, on demand, they could bring all their employees, customers, suppliers, and partners together in a virtual room, with shared access to every modern communications and computing channel. They should take a fresh look at their business processes to find points at which richer and more customizable communications could eliminate bottlenecks and enhance quality. The important dividing line won't be between those who deploy Vol P and those who don't, or even between early adopters and laggards. It will be between those who see Vol P as just a new way to do the same old things and those who use itto rethink their entire businesses.

  16. IPS observation system for the Miyun 50 m radio telescope and its commissioning observation

    International Nuclear Information System (INIS)

    Zhu Xinying; Zhang Xizhen; Zhang Hongbo; Kong Deqing; Qu Huipeng

    2012-01-01

    Ground-based observation of Interplanetary Scintillation (IPS) is an important approach for monitoring solar wind. A ground-based IPS observation system has been newly implemented on a 50 m radio telescope at Miyun station, managed by the National Astronomical Observatories, Chinese Academy of Sciences. This observation system has been constructed for the purpose of observing solar wind speed and the associated scintillation index by using the normalized cross-spectrum of a simultaneous dual-frequency IPS measurement. The system consists of a universal dual-frequency front-end and a dual-channel multi-function back-end specially designed for IPS. After careful calibration and testing, IPS observations on source 3C 273B and 3C 279 have been successfully carried out. The preliminary observation results show that this newly-developed observation system is capable of performing IPS observation. The system's sensitivity for IPS observation can reach over 0.3 Jy in terms of an IPS polarization correlator with 4 MHz bandwidth and 2 s integration time. (research papers)

  17. Mobile IP and protocol authentication extension

    OpenAIRE

    Nguyen, Phuc V.

    2011-01-01

    Mobile IP is an open standard, defined by the Internet Engineering Task Force (IETF) RFC 3220. By using Mobile IP, you can keep the same IP address, stay connected, and maintain ongoing applications while roaming between IP networks. Mobile IP is scalable for the Internet because it is based on IP - any media that can support IP can support Mobile IP.

  18. Integrated power electronic converters and digital control

    CERN Document Server

    Emadi, Ali; Nie, Zhong

    2009-01-01

    Non-isolated DC-DC ConvertersBuck ConverterBoost ConverterBuck-Boost ConverterIsolated DC-DC ConvertersFlyback ConverterForward ConverterPush-Pull ConverterFull-Bridge ConverterHalf-Bridge ConverterPower Factor CorrectionConcept of PFCGeneral Classification of PFC CircuitsHigh Switching Frequency Topologies for PFCApplication of PFC in Advanced Motor DrivesIntegrated Switched-Mode Power ConvertersSwitched-Mode Power SuppliesThe Concept of Integrated ConverterDefinition of Integrated Switched-Mode Power Supplies (ISMPS)Boost-Type Integrated TopologiesGeneral Structure of Boost-Type Integrated T

  19. RIDES: Robust Intrusion Detection System for IP-Based Ubiquitous Sensor Networks

    Directory of Open Access Journals (Sweden)

    Sungwon Lee

    2009-05-01

    Full Text Available TheIP-based Ubiquitous Sensor Network (IP-USN is an effort to build the “Internet of things”. By utilizing IP for low power networks, we can benefit from existing well established tools and technologies of IP networks. Along with many other unresolved issues, securing IP-USN is of great concern for researchers so that future market satisfaction and demands can be met. Without proper security measures, both reactive and proactive, it is hard to envisage an IP-USN realm. In this paper we present a design of an IDS (Intrusion Detection System called RIDES (Robust Intrusion DEtection System for IP-USN. RIDES is a hybrid intrusion detection system, which incorporates both Signature and Anomaly based intrusion detection components. For signature based intrusion detection this paper only discusses the implementation of distributed pattern matching algorithm with the help of signature-code, a dynamically created attack-signature identifier. Other aspects, such as creation of rules are not discussed. On the other hand, for anomaly based detection we propose a scoring classifier based on the SPC (Statistical Process Control technique called CUSUM charts. We also investigate the settings and their effects on the performance of related parameters for both of the components.

  20. Impact of genome assembly status on ChIP-Seq and ChIP-PET data mapping

    Directory of Open Access Journals (Sweden)

    Sachs Laurent

    2009-12-01

    Full Text Available Abstract Background ChIP-Seq and ChIP-PET can potentially be used with any genome for genome wide profiling of protein-DNA interaction sites. Unfortunately, it is probable that most genome assemblies will never reach the quality of the human genome assembly. Therefore, it remains to be determined whether ChIP-Seq and ChIP-PET are practicable with genome sequences other than a few (e.g. human and mouse. Findings Here, we used in silico simulations to assess the impact of completeness or fragmentation of genome assemblies on ChIP-Seq and ChIP-PET data mapping. Conclusions Most currently published genome assemblies are suitable for mapping the short sequence tags produced by ChIP-Seq or ChIP-PET.

  1. ejIP: A TCP/IP Stack for Embedded Java

    DEFF Research Database (Denmark)

    Schoeberl, Martin

    2011-01-01

    present the design and implementation of a network stack written entirely in Java. This implementation serves as an example how to implement system functions in a safe language and gives evidence that Java can be used for operating system related functionality. The described TCP/IP stack ejIP has already...

  2. APLIKASI SERVER VIRTUAL IP UNTUK MIKROKONTROLER

    OpenAIRE

    Ashari, Ahmad

    2008-01-01

    Selama ini mikrokontroler yang terhubung ke satu komputer hanya dapat diakses melalui satu IP saja, padahal kebanyakan sistem operasi sekarang dapat memperjanjikan lebih dari satu IP untuk setiap komputer dalam bentuk virtual IP. Penelitian ini mengkaji pemanfaatan virtual IP dari IP aliasing pada sistem operasi Linux sebagai Server Virtual IP untuk mikrokontroler. Prinsip dasar Server Virtual IP adalah pembuatan Virtual Host pada masing-masing IP untuk memproses paket-paket data dan menerjem...

  3. Low-power digital ASIC for on-chip spectral analysis of low-frequency physiological signals

    International Nuclear Information System (INIS)

    Nie Zedong; Zhang Fengjuan; Li Jie; Wang Lei

    2012-01-01

    A digital ASIC chip customized for battery-operated body sensing devices is presented. The ASIC incorporates a novel hybrid-architecture fast Fourier transform (FFT) unit that is capable of scalable spectral analysis, a licensed ARM7TDMI IP hardcore and several peripheral IP blocks. Extensive experimental results suggest that the complete chip works as intended. The power consumption of the FFT unit is 0.69 mW at 1 MHz with 1.8 V power supply. The low-power and programmable features of the ASIC make it suitable for ‘on-the-fly’ low-frequency physiological signal processing. (semiconductor integrated circuits)

  4. Design of IP Camera Access Control Protocol by Utilizing Hierarchical Group Key

    Directory of Open Access Journals (Sweden)

    Jungho Kang

    2015-08-01

    Full Text Available Unlike CCTV, security video surveillance devices, which we have generally known about, IP cameras which are connected to a network either with or without wire, provide monitoring services through a built-in web-server. Due to the fact that IP cameras can use a network such as the Internet, multiple IP cameras can be installed at a long distance and each IP camera can utilize the function of a web server individually. Even though IP cameras have this kind of advantage, it has difficulties in access control management and weakness in user certification, too. Particularly, because the market of IP cameras did not begin to be realized a long while ago, systems which are systematized from the perspective of security have not been built up yet. Additionally, it contains severe weaknesses in terms of access authority to the IP camera web server, certification of users, and certification of IP cameras which are newly installed within a network, etc. This research grouped IP cameras hierarchically to manage them systematically, and provided access control and data confidentiality between groups by utilizing group keys. In addition, IP cameras and users are certified by using PKI-based certification, and weak points of security such as confidentiality and integrity, etc., are improved by encrypting passwords. Thus, this research presents specific protocols of the entire process and proved through experiments that this method can be actually applied.

  5. Energy star compliant voice over internet protocol (VoIP) telecommunications network including energy star compliant VoIP devices

    Science.gov (United States)

    Kouchri, Farrokh Mohammadzadeh

    2012-11-06

    A Voice over Internet Protocol (VoIP) communications system, a method of managing a communications network in such a system and a program product therefore. The system/network includes an ENERGY STAR (E-star) aware softswitch and E-star compliant communications devices at system endpoints. The E-star aware softswitch allows E-star compliant communications devices to enter and remain in power saving mode. The E-star aware softswitch spools messages and forwards only selected messages (e.g., calls) to the devices in power saving mode. When the E-star compliant communications devices exit power saving mode, the E-star aware softswitch forwards spooled messages.

  6. Power up your plant - An introduction to integrated process and power automation

    Energy Technology Data Exchange (ETDEWEB)

    Vasel, Jeffrey

    2010-09-15

    This paper discusses how a single integrated system can increase energy efficiency, improve plant uptime, and lower life cycle costs. Integrated Process and Power Automation is a new system integration architecture and power strategy that addresses the needs of the process and power generation industries. The architecture is based on Industrial Ethernet standards such as IEC 61850 and Profinet as well as Fieldbus technologies. The energy efficiency gains from integration are discussed in a power generation use case. A power management system success story from a major oil and gas company, Petrobras, is also discussed.

  7. Dynamic Reactive Power Compensation of Large Scale Wind Integrated Power System

    DEFF Research Database (Denmark)

    Rather, Zakir Hussain; Chen, Zhe; Thøgersen, Paul

    2015-01-01

    wind turbines especially wind farms with additional grid support functionalities like dynamic support (e,g dynamic reactive power support etc.) and ii) refurbishment of existing conventional central power plants to synchronous condensers could be one of the efficient, reliable and cost effective option......Due to progressive displacement of conventional power plants by wind turbines, dynamic security of large scale wind integrated power systems gets significantly compromised. In this paper we first highlight the importance of dynamic reactive power support/voltage security in large scale wind...... integrated power systems with least presence of conventional power plants. Then we propose a mixed integer dynamic optimization based method for optimal dynamic reactive power allocation in large scale wind integrated power systems. One of the important aspects of the proposed methodology is that unlike...

  8. Modeling ChIP sequencing in silico with applications.

    Directory of Open Access Journals (Sweden)

    Zhengdong D Zhang

    2008-08-01

    Full Text Available ChIP sequencing (ChIP-seq is a new method for genomewide mapping of protein binding sites on DNA. It has generated much excitement in functional genomics. To score data and determine adequate sequencing depth, both the genomic background and the binding sites must be properly modeled. To develop a computational foundation to tackle these issues, we first performed a study to characterize the observed statistical nature of this new type of high-throughput data. By linking sequence tags into clusters, we show that there are two components to the distribution of tag counts observed in a number of recent experiments: an initial power-law distribution and a subsequent long right tail. Then we develop in silico ChIP-seq, a computational method to simulate the experimental outcome by placing tags onto the genome according to particular assumed distributions for the actual binding sites and for the background genomic sequence. In contrast to current assumptions, our results show that both the background and the binding sites need to have a markedly nonuniform distribution in order to correctly model the observed ChIP-seq data, with, for instance, the background tag counts modeled by a gamma distribution. On the basis of these results, we extend an existing scoring approach by using a more realistic genomic-background model. This enables us to identify transcription-factor binding sites in ChIP-seq data in a statistically rigorous fashion.

  9. Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq

    NARCIS (Netherlands)

    Johannes, Frank; Wardenaar, Rene; Colomé Tatché, Maria; Mousson, Florence; de Graaf, Petra; Mokry, Michal; Guryev, Victor; Timmers, H. Th. Marc; Cuppen, Edwin; Jansen, Ritsert C.; Bateman, Alex

    2010-01-01

    Motivation: ChIP-chip and ChIP-seq technologies provide genomewide measurements of various types of chromatin marks at an unprecedented resolution. With ChIP samples collected from different tissue types and/ or individuals, we can now begin to characterize stochastic or systematic changes in

  10. Integration of 128 channels for monitoring, acquisition and control with existing LHCD DAC system

    International Nuclear Information System (INIS)

    Joshi, Ramesh; Virani, Chetan; Wadhwani, Archana; Sharma, P.K.

    2015-01-01

    Lower Hybrid Current Drive (LHCD) data acquisition system needs to be upgraded for additional channel requirement. The existing VME based DAC has been used since long with 32 analog input channels for data monitoring and control. Additional 128 channels require integrating with existing DAC. There are four layers of waveguides which deliver final output power into tokamak. Each layer requires 32 channels for power measurement. For the same requirement 128 analog input channels have been integrated with the help of carrier board and IP modules. Acromag IP330 modules have been procured and finally integrated with additional carrier board with existing VME hardware. Each module provides 32 analog input channels. Device driver has been developed for each module and integrated with existing program. LHCD DAC system has been upgraded with additional 128 channels requirement. It has been successfully testing with recent SST-1 campaign. (author)

  11. Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq

    NARCIS (Netherlands)

    Johannes, F.; Wardenaar, R.; Colome-Tatche, M.; Mousson, F.; de Graaf, P.; Mokry, M.; Guryev, V.; Timmers, H.T.; Cuppen, E.; Jansen, R.

    2010-01-01

    MOTIVATION: ChIP-chip and ChIP-seq technologies provide genome-wide measurements of various types of chromatin marks at an unprecedented resolution. With ChIP samples collected from different tissue types and/or individuals, we can now begin to characterize stochastic or systematic changes in

  12. Penggunaan Media Presentase Microsoft Power Point Untuk Meningkatkan Hasil Belajar IPS Terpadu Pada Siswa Kelas VIII a SMP Negeri 2 Tanantovea

    OpenAIRE

    Hitler, Ahmad

    2014-01-01

    Permasalahan yang diangkat dalam penelitian adalah apakah dengan penggunaan media Presentase Microsoft Power Point pada mata pembelajaran IPS Terpadu dapat meningkatkan hasil belajar siswa kelas VIII A di SMP Negeri 2 Tanantovea. Penelitian ini bertujuan untuk meningkatkan hasil belajar siswa pada pokok bahasan Kolonialisme dan Imperialisme Barat di kelas VIII A SMP Negeri 2 Tanantovea. Penelitian ini dilakukan dalam 2 siklus, setiap siklus terdiri dari perencanaan, pelaksanaan tindakan, obs...

  13. Optimizing hourly hydro operations at the Salt Lake City Area integrated projects

    International Nuclear Information System (INIS)

    Veselka, T.D.; Hamilton, S.; McCoy, J.

    1995-01-01

    The Salt Lake City Area (SLCA) office of the Western Area Power Administration (Western) is responsible for marketing the capacity and energy generated by the Colorado Storage, Collbran, and Rio Grande hydropower projects. These federal resources are collectively called the Salt Lake City Area Integrated Projects (SLCA/IP). In recent years, stringent operational limitations have been placed on several of these hydropower plants including the Glen Canyon Dam, which accounts for approximately 80% of the SLCA/IP resources. Operational limitations on SLCA/IP hydropower plants continue to evolve as a result of decisions currently being made in the Glen Canyon Dam Environmental Impact Statement (EIS) and the Power Marketing EIS. To analyze a broad range of issues associated with many possible future operational restrictions, Argonne National Laboratory (ANL), with technical assistance from Western has developed the Hydro LP (Linear Program) Model. This model simulates hourly operations at SLCA/IP hydropower plants for weekly periods with the objective of maximizing Western's net revenues. The model considers hydropower operations for the purpose of serving SLCA firm loads, loads for special projects, Inland Power Pool (IPP) spinning reserve requirements, and Western's purchasing programs. The model estimates hourly SLCA/IP generation and spot market activities. For this paper, hourly SLCA/IP hydropower plant generation is simulated under three operational scenarios and three hydropower conditions. For each scenario an estimate of Western's net revenue is computed

  14. Implementasi Sistem IP PBX menggunakan Briker

    Directory of Open Access Journals (Sweden)

    DWI ARYANTA

    2017-06-01

    Full Text Available Abstrak VoIP (Voice over Internet Protocol adalah komunikasi suara jarak jauh yang digunakan melalui jaringan IP. Pada penelitian ini dirancang sistem IP PBX dengan menggunakan teknologi berbasis VoIP. IP PBX adalah perangkat switching komunikasi telepon dan data berbasis teknologi Internet Protocol (IP yang mengendalikan ekstension telepon analog maupun ekstension IP Phone. Software VirtualBox digunakan dengan tujuan agar lebih memudahkan dalam sistem pengoperasian Linux yang dimana program untuk membuat IP PBX adalah menggunakan Briker yang bekerja pada Operating System Linux 2.6. Setelah proses penginstalan Briker pada Virtualbox dilakukan implementasi jaringan IP PBX. Setelah mengimplementasikan jaringan IP PBX sesuai dengan topologi, kemudian melakukan pengujian success call rate dan analisis Quality of Service (QoS. Pengukuran QoS menggunakan parameter jitter, delay, dan packet loss yang dihasilkan dalam sistem IP PBX ini. Nilai jitter sesama user Briker (baik pada smartphone maupun komputer mempunyai rata-rata berada pada nilai 16,77 ms. Sedangkan nilai packetloss yang didapat pada saat terdapat pada saat user 1 sebagai pemanggil telepon adalah 0%. Sedangkan persentase packet loss pada saat user 1 sebagai penerima telepon adalah 0,01%. Nilai delay pada saat berkomunikasi antar user berada pada 11,75 ms. Secara keseluruhan nilai yang didapatkan melalui penelitian ini, dimana hasil pengujian parameter-parameter QOS sesuai dengan standar yang telah direkomendasikan oleh ITU dan didapatkan nilai QoS dengan hasil “baik”. Kata Kunci : Briker, VoIP, QoS, IP PBX, Smartphone. Abstract VoIP (Voice over Internet Protocol is a long-distance voice communications over IP networks are used. In this study, IP PBX systems designed using VoIP -based technologies. IP PBX is a telephone switching device and data communication technology-based Internet Protocol (IP which controls the analog phone extensions and IP Phone extensions. VirtualBox software is

  15. Analysis of ChIP-seq Data in R/Bioconductor.

    Science.gov (United States)

    de Santiago, Ines; Carroll, Thomas

    2018-01-01

    The development of novel high-throughput sequencing methods for ChIP (chromatin immunoprecipitation) has provided a very powerful tool to study gene regulation in multiple conditions at unprecedented resolution and scale. Proactive quality-control and appropriate data analysis techniques are of critical importance to extract the most meaningful results from the data. Over the last years, an array of R/Bioconductor tools has been developed allowing researchers to process and analyze ChIP-seq data. This chapter provides an overview of the methods available to analyze ChIP-seq data based primarily on software packages from the open-source Bioconductor project. Protocols described in this chapter cover basic steps including data alignment, peak calling, quality control and data visualization, as well as more complex methods such as the identification of differentially bound regions and functional analyses to annotate regulatory regions. The steps in the data analysis process were demonstrated on publicly available data sets and will serve as a demonstration of the computational procedures routinely used for the analysis of ChIP-seq data in R/Bioconductor, from which readers can construct their own analysis pipelines.

  16. Integrated Wind Power Planning Tool

    DEFF Research Database (Denmark)

    Rosgaard, M. H.; Giebel, Gregor; Nielsen, T. S.

    2012-01-01

    model to be developed in collaboration with ENFOR A/S; a danish company that specialises in forecasting and optimisation for the energy sector. This integrated prediction model will allow for the description of the expected variability in wind power production in the coming hours to days, accounting......This poster presents the current state of the public service obligation (PSO) funded project PSO 10464, with the working title "Integrated Wind Power Planning Tool". The project commenced October 1, 2011, and the goal is to integrate a numerical weather prediction (NWP) model with purely...

  17. In vitro synthesis and purification of PhIP-deoxyguanosine and PhIP-DNA oligomer covalent complexes

    Energy Technology Data Exchange (ETDEWEB)

    Freeman, J.

    1994-12-01

    2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a heterocyclic amine compound formed when meats are cooked at high temperatures. PhIP damages DNA by forming covalent complexes with DNA carcinogen. In an effort to understand how the binding of PhIP to DNA may cause cancer, it is important to characterize the structures of PhIP-damaged DNA molecules. Our HPLC data support fluorescence and {sup 32}P Post-labeling studies which indicate the formation of several species of 2{prime}deoxyguanosine-(dG) or oligodeoxynucleotide-PhIP adducts. The reaction of PhIP with dG resulted in a reddish precipitate that was likely the major adduct, N-(deoxyguanosin-8-yl)-PhIP (dG-C8-PhIP) adduct, with a more polar adduct fraction remaining in the supernatant. Reversed-phase HPLC analysis of the adducts in the supernatant revealed the existence of species of much shorter retention times than the dG-C8-PhIP adduct, confirming that these species are more polar than dG-C8-PhIP. At least four adducts were formed in the reaction of PhIP with DNA oligomer. HPLC analysis of the PhIP-DNA oligomer supernatant after butanol extractions revealed four unresolved peaks which spectra had maximum wavelengths between 340 and 360 nm. Though adduct peaks were not completely resolved, there was {approximately}3 minutes interval between the DNA oligomer peak and the adduct peaks. Furthermore, fluorescence emission data of the DNA oligomer-PhIP adduct solution show heterogeneous binding. The more polar PhIP adducts were fraction-collected and their structures will be solved by nuclear magnetic resonance or x-ray crystallography.

  18. Ensuring Software IP Cleanliness

    OpenAIRE

    Mahshad Koohgoli; Richard Mayer

    2007-01-01

    At many points in the life of a software enterprise, determination of intellectual property (IP) cleanliness becomes critical. The value of an enterprise that develops and sells software may depend on how clean the software is from the IP perspective. This article examines various methods of ensuring software IP cleanliness and discusses some of the benefits and shortcomings of current solutions.

  19. Generation of urine iPS cell line from a patient with obsessive-compulsive disorder using a non-integrative method

    Directory of Open Access Journals (Sweden)

    Jaroslaw Sochacki

    2016-07-01

    Full Text Available Urine sample was collected from a 29-year-old male patient with an early onset form of DSM-5 obsessive-compulsive disorder (OCD, comorbid body dysmorphic and excoriation (skin-picking disorders, and a positive family history for OCD. Urine cell line was established and expanded for the reprogramming procedure. Induced pluripotent stem (iPS cells were derived using the integration-free CytoTune®-iPS 2.0 Sendai Reprogramming Kit, which includes Sendai virus particles of the four Yamanaka factors Oct3/4, Sox2, Klf4 and c-Myc.

  20. Gevaar VoIP voor telecomsector overdreven

    NARCIS (Netherlands)

    Deventer, M.O. van; Wegberg, M. van

    2004-01-01

    Het is een hype Voice-over-IP (VoIP) voor te stellen als een ontwrichtende technologie die de telecomindustrie ingrijpend zal veranderen. Maar hoe ontwrichtend is VoIP eigenlijk? Oskar van Deventer en Marc van Wegberg analyseren drie vormen van VoIP en laten zien dat alleen ‘VoIP-chat’ potentieel

  1. Space Network IP Services (SNIS): An Architecture for Supporting Low Earth Orbiting IP Satellite Missions

    Science.gov (United States)

    Israel, David J.

    2005-01-01

    The NASA Space Network (SN) supports a variety of missions using the Tracking and Data Relay Satellite System (TDRSS), which includes ground stations in White Sands, New Mexico and Guam. A Space Network IP Services (SNIS) architecture is being developed to support future users with requirements for end-to-end Internet Protocol (IP) communications. This architecture will support all IP protocols, including Mobile IP, over TDRSS Single Access, Multiple Access, and Demand Access Radio Frequency (RF) links. This paper will describe this architecture and how it can enable Low Earth Orbiting IP satellite missions.

  2. Ensuring Software IP Cleanliness

    Directory of Open Access Journals (Sweden)

    Mahshad Koohgoli

    2007-12-01

    Full Text Available At many points in the life of a software enterprise, determination of intellectual property (IP cleanliness becomes critical. The value of an enterprise that develops and sells software may depend on how clean the software is from the IP perspective. This article examines various methods of ensuring software IP cleanliness and discusses some of the benefits and shortcomings of current solutions.

  3. How to Integrate Variable Power Source into a Power Grid

    Science.gov (United States)

    Asano, Hiroshi

    This paper discusses how to integrate variable power source such as wind power and photovoltaic generation into a power grid. The intermittent renewable generation is expected to penetrate for less carbon intensive power supply system, but it causes voltage control problem in the distribution system, and supply-demand imbalance problem in a whole power system. Cooperative control of customers' energy storage equipment such as water heater with storage tank for reducing inverse power flow from the roof-top PV system, the operation technique using a battery system and the solar radiation forecast for stabilizing output of variable generation, smart charging of plug-in hybrid electric vehicles for load frequency control (LFC), and other methods to integrate variable power source with improving social benefits are surveyed.

  4. Wireless Power Transfer Roadway Integration

    OpenAIRE

    Gardner, Trevor

    2017-01-01

    Electric vehicles represent a major accomplishment in the energy and transportation industry. Unfortunately, they are restricted to a small travel range because of limited battery life. Successful integration of wireless power transfer (WPT) systems into the infrastructure would remove the range restrictions of EVs. To successfully integrate this technology, several requirements must be met. First, the embedment process cannot interfere with the electrical performance of the inductive power t...

  5. Bayesian modeling of ChIP-chip data using latent variables.

    KAUST Repository

    Wu, Mingqi; Liang, Faming; Tian, Yanan

    2009-01-01

    and plants. Various methods have been proposed in the literature for analyzing the ChIP-chip data, such as the sliding window methods, the hidden Markov model-based methods, and Bayesian methods. Although, due to the integrated consideration of uncertainty

  6. Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis

    Directory of Open Access Journals (Sweden)

    J. Travis Hinson

    2016-12-01

    Full Text Available AMP-activated protein kinase (AMPK is a metabolic enzyme that can be activated by nutrient stress or genetic mutations. Missense mutations in the regulatory subunit, PRKAG2, activate AMPK and cause left ventricular hypertrophy, glycogen accumulation, and ventricular pre-excitation. Using human iPS cell models combined with three-dimensional cardiac microtissues, we show that activating PRKAG2 mutations increase microtissue twitch force by enhancing myocyte survival. Integrating RNA sequencing with metabolomics, PRKAG2 mutations that activate AMPK remodeled global metabolism by regulating RNA transcripts to favor glycogen storage and oxidative metabolism instead of glycolysis. As in patients with PRKAG2 cardiomyopathy, iPS cell and mouse models are protected from cardiac fibrosis, and we define a crosstalk between AMPK and post-transcriptional regulation of TGFβ isoform signaling that has implications in fibrotic forms of cardiomyopathy. Our results establish critical connections among metabolic sensing, myocyte survival, and TGFβ signaling.

  7. Implementasi Protokol Keamanan TLS pada Aplikasi Layanan Komunikasi Suara Melalui Jaringan TCP/IP (VoIP)

    OpenAIRE

    Hariady, Ricky

    2011-01-01

    Saat ini layanan komunikasi suara melalui jaringan TCP/IP atau yang lebih dikenal dengan VoIP (Voice over IP) telah semakin banyak digunakan, namun teknologi VoIP yang ada saat ini masih rentan terhadap penyadapan ataupun pencurian data. Sementara protokol kriptografi TLS (Transport Layer Security) telah teruji dan banyak digunakan untuk mengamankan komunikasi melalui internet seperti pada layanan email dan web. Dengan mengimplementasikan protokol TLS pada sebuah aplikasi Vo...

  8. A distributed control approach for power and energy management in a notional shipboard power system

    Science.gov (United States)

    Shen, Qunying

    The main goal of this thesis is to present a power control module (PCON) based approach for power and energy management and to examine its control capability in shipboard power system (SPS). The proposed control scheme is implemented in a notional medium voltage direct current (MVDC) integrated power system (IPS) for electric ship. To realize the control functions such as ship mode selection, generator launch schedule, blackout monitoring, and fault ride-through, a PCON based distributed power and energy management system (PEMS) is developed. The control scheme is proposed as two-layer hierarchical architecture with system level on the top as the supervisory control and zonal level on the bottom as the decentralized control, which is based on the zonal distribution characteristic of the notional MVDC IPS that was proposed as one of the approaches for Next Generation Integrated Power System (NGIPS) by Norbert Doerry. Several types of modules with different functionalities are used to derive the control scheme in detail for the notional MVDC IPS. Those modules include the power generation module (PGM) that controls the function of generators, the power conversion module (PCM) that controls the functions of DC/DC or DC/AC converters, etc. Among them, the power control module (PCON) plays a critical role in the PEMS. It is the core of the control process. PCONs in the PEMS interact with all the other modules, such as power propulsion module (PPM), energy storage module (ESM), load shedding module (LSHED), and human machine interface (HMI) to realize the control algorithm in PEMS. The proposed control scheme is implemented in real time using the real time digital simulator (RTDS) to verify its validity. To achieve this, a system level energy storage module (SESM) and a zonal level energy storage module (ZESM) are developed in RTDS to cooperate with PCONs to realize the control functionalities. In addition, a load shedding module which takes into account the reliability

  9. Development of an integrated campus security alerting system ...

    African Journals Online (AJOL)

    This work presents an integrated alerting system which uses both the Internet Protocol (IP) cameras and micro-switches for monitoring security situations thereby providing an immediate alerting signal to the security personnel. The system has the input unit, processing unit, control unit and the power supply unit as its ...

  10. A survey of Attacks on VoIP networks and Countermeasures

    African Journals Online (AJOL)

    PROF. OLIVER OSUAGWA

    2015-06-01

    Jun 1, 2015 ... integrity and availability of the services rendered on VoIP networks. In this paper, the various ... described in [2] and [5], denial of service in [1], eavesdropping ..... distributed denial of service (DDoS) [9],. [2]. •. Session initiation ...

  11. Power management techniques for integrated circuit design

    CERN Document Server

    Chen, Ke-Horng

    2016-01-01

    This book begins with the premise that energy demands are directing scientists towards ever-greener methods of power management, so highly integrated power control ICs (integrated chip/circuit) are increasingly in demand for further reducing power consumption. * A timely and comprehensive reference guide for IC designers dealing with the increasingly widespread demand for integrated low power management * Includes new topics such as LED lighting, fast transient response, DVS-tracking and design with advanced technology nodes * Leading author (Chen) is an active and renowned contributor to the power management IC design field, and has extensive industry experience * Accompanying website includes presentation files with book illustrations, lecture notes, simulation circuits, solution manuals, instructors manuals, and program downloads.

  12. The challenge of integrating large scale wind power

    Energy Technology Data Exchange (ETDEWEB)

    Kryszak, B.

    2007-07-01

    The support of renewable energy sources is one of the key issues in current energy policies. The paper presents aspects of the integration of wind power in the electric power system from the perspective of a Transmission System Operator (TSO). Technical, operational and market aspects related to the integration of more than 8000 MW of installed wind power into the Transmission Network of Vattenfall Europe Transmission are discussed, and experiences with the transmission of wind power, wind power prediction, balancing of wind power, power production behaviour and fluctuations are reported. Moreover, issues for wind power integration on a European level will be discussed with the background of a wind power study. (auth)

  13. An IP-oriented 11-bit 160 MS/s 2-channel current-steering DAC

    International Nuclear Information System (INIS)

    Xu Ning; Li Fule; Zhang Chun; Wang Zhihua

    2014-01-01

    This paper presents an 11-bit 160 MS/s 2-channel current-steering digital-to-analog converter (DAC) IP. The circuit and layout are carefully designed to optimize its performance and area. A 6-2-3 segmented structure is used for the trade-off among linearity, area and layout complexity. The sizes of current source transistors are calculated out according to the process matching parameter. The unary current cells are placed in a one-dimension distribution to simplify the layout routing, spare area and wiring layer. Their sequences are also carefully designed to reduce integral nonlinearity. The test result presents an SFDR of 72 dBc at 4.88 MHz input signal with DNL ⩽ 0.25 LSB, INL ⩽ 0.8 LSB. The full-scale output current is 5 mA with a 2.5 V analog power supply. The core of each channel occupies 0.08 mm 2 in a 1P-8M 55 nm CMOS process. (semiconductor integrated circuits)

  14. Wind power integration connection and system operational aspects

    CERN Document Server

    Fox, Brendan

    2014-01-01

    Wind Power Integration provides a wide-ranging discussion on all major aspects of wind power integration into electricity supply systems. This second edition has been fully revised and updated to take account of the significant growth in wind power deployment in the past few years. New discussions have been added to describe developments in wind turbine generator technology and control, the network integration of wind power, innovative ways to integrate wind power when its generation potential exceeds 50% of demand, case studies on how forecasting errors have affected system operation, and an update on how the wind energy sector has fared in the marketplace. Topics covered include: the development of wind power technology and its world-wide deployment; wind power technology and the interaction of various wind turbine generator types with the utility network; and wind power forecasting and the challenges faced by wind energy in modern electricity markets.

  15. Real-time impact of power balancing on power system operation with large scale integration of wind power

    DEFF Research Database (Denmark)

    Basit, Abdul; Hansen, Anca Daniela; Sørensen, Poul Ejnar

    2017-01-01

    Highly wind power integrated power system requires continuous active power regulation to tackle the power imbalances resulting from the wind power forecast errors. The active power balance is maintained in real-time with the automatic generation control and also from the control room, where...... power system model. The power system model takes the hour-ahead regulating power plan from power balancing model and the generation and power exchange capacities for the year 2020 into account. The real-time impact of power balancing in a highly wind power integrated power system is assessed...

  16. IPs

    African Journals Online (AJOL)

    Fr. Ikenga

    special rights to the under-privileged IPs based on their culture, religion and .... and exploitation of natural resources, political determination and autonomy, .... supportive and sustaining.33Balancing individualism and communalism will avoid ...

  17. VoIP Accessibility: A Usability Study of Voice over Internet Protocol (VoIP) Systems and A Survey of VoIP Users with Vision Loss

    Science.gov (United States)

    Packer, Jaclyn; Reuschel, William

    2018-01-01

    Introduction: Accessibility of Voice over Internet Protocol (VoIP) systems was tested with a hands-on usability study and an online survey of VoIP users who are visually impaired. The survey examined the importance of common VoIP features, and both methods assessed difficulty in using those features. Methods: The usability test included four paid…

  18. Offloading IP Flows onto Lambda-Connections

    NARCIS (Netherlands)

    Fioreze, Tiago; Oude Wolbers, Mattijs; van de Meent, R.; Pras, Aiko

    2007-01-01

    Optical networks are capable of switching IP traffic via lambda connections. In this way, big IP flows that overload the regular IP routing level may be moved to the optical level, where they get better Quality of Service (QoS). At the same time, the IP routing level is off-loaded and can serve

  19. Mobile IP: Security & application

    NARCIS (Netherlands)

    Tuquerres, G.; Salvador, M.R.; Sprenkels, Ron

    1999-01-01

    As required in the TGS Mobile IP Advanced Module, this paper presents a survey of common security threats which mobile IP networks are exposed to as well as some proposed solutions to deal with such threats.

  20. Predictive IP controller for robust position control of linear servo system.

    Science.gov (United States)

    Lu, Shaowu; Zhou, Fengxing; Ma, Yajie; Tang, Xiaoqi

    2016-07-01

    Position control is a typical application of linear servo system. In this paper, to reduce the system overshoot, an integral plus proportional (IP) controller is used in the position control implementation. To further improve the control performance, a gain-tuning IP controller based on a generalized predictive control (GPC) law is proposed. Firstly, to represent the dynamics of the position loop, a second-order linear model is used and its model parameters are estimated on-line by using a recursive least squares method. Secondly, based on the GPC law, an optimal control sequence is obtained by using receding horizon, then directly supplies the IP controller with the corresponding control parameters in the real operations. Finally, simulation and experimental results are presented to show the efficiency of proposed scheme. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

  1. Voice over IP Security

    CERN Document Server

    Keromytis, Angelos D

    2011-01-01

    Voice over IP (VoIP) and Internet Multimedia Subsystem technologies (IMS) are rapidly being adopted by consumers, enterprises, governments and militaries. These technologies offer higher flexibility and more features than traditional telephony (PSTN) infrastructures, as well as the potential for lower cost through equipment consolidation and, for the consumer market, new business models. However, VoIP systems also represent a higher complexity in terms of architecture, protocols and implementation, with a corresponding increase in the potential for misuse. In this book, the authors examine the

  2. Design of ion-pump power supply control software system based on TCP/IP protocol

    International Nuclear Information System (INIS)

    Lin Feiyu; Huang Jijiang; Guo Yuhui; Fang Zheng; Wang Yanyu

    2009-01-01

    This paper discuss a Ion-pump Power Supply control system making use of RS232 series bus and Intranet. The system's hardware VAC800 is composed of MSP430F149 mixed-signal processors produced by TI and UA7000A network model. MSP430F149 has advantages of ultra-low-power and high-integration. The Ion-pump Power Supply control system has the characteristics of strong function, simple structure, high reliability, strong resistance of noise, no peripheral chip, etc. Visual studio 2005 is used to design the system's software. The Ion-pump Power supplier control system can remotely monitor and control Ion-pump Power Suppliers. (authors)

  3. Telefonía IP (ToIP): principios fundamentales, arquitectura y aspecto regulatorio en el Ecuador

    OpenAIRE

    Narváez García, William Fernando; Ugalde Peña, Pablo Esteban

    2006-01-01

    En este documento, hemos tratado de explicar el funcionamiento de la telefonía IP dentro de poco, comenzamos hablando con una introducción al tema al comentar sobre la actual tendencia a la conocida como patrón ALL-IP. Luego hemos visto conveniente hacer un comentario acerca de la evolución de las telecomunicaciones desde sus primeros pasos con Guillermo Marconi hasta nuestros días con la ToIP. De modo que existe un concepto claro de lo que la ToIP significa, en primer lugar se explica ...

  4. CanOpen on RASTA: The Integration of the CanOpen IP Core in the Avionics Testbed

    Science.gov (United States)

    Furano, Gianluca; Guettache, Farid; Magistrati, Giorgio; Tiotto, Gabriele; Ortega, Carlos Urbina; Valverde, Alberto

    2013-08-01

    This paper presents the work done within the ESA Estec Data Systems Division, targeting the integration of the CanOpen IP Core with the existing Reference Architecture Test-bed for Avionics (RASTA). RASTA is the reference testbed system of the ESA Avionics Lab, designed to integrate the main elements of a typical Data Handling system. It aims at simulating a scenario where a Mission Control Center communicates with on-board computers and systems through a TM/TC link, thus providing the data management through qualified processors and interfaces such as Leon2 core processors, CAN bus controllers, MIL-STD-1553 and SpaceWire. This activity aims at the extension of the RASTA with two boards equipped with HurriCANe controller, acting as CANOpen slaves. CANOpen software modules have been ported on the RASTA system I/O boards equipped with Gaisler GR-CAN controller and acts as master communicating with the CCIPC boards. CanOpen serves as upper application layer for based on CAN defined within the CAN-in-Automation standard and can be regarded as the definitive standard for the implementation of CAN-based systems solutions. The development and integration of CCIPC performed by SITAEL S.p.A., is the first application that aims to bring the CANOpen standard for space applications. The definition of CANOpen within the European Cooperation for Space Standardization (ECSS) is under development.

  5. IP Infrastructure Geolocation

    Science.gov (United States)

    2015-03-01

    by non-commercial enti- ties. HostiP is a community-driven geolocation service. It provides an Application Pro- gramming Interface ( API ) for...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS IP INFRASTRUCTURE GEOLOCATION Thesis Advisor: Second Reader: by Guan Yan Cai March...FUNDING NUMBERS IP INFRASTRUCfURE GEOLOCATION N66001-2250-59231 6. AUTHOR(S) Guan Yan Cai 7. PERFORMING ORGANIZATION NAME(S) AND AOORESS(ES) 9

  6. Fundamentals of power integrity for computer platforms and systems

    CERN Document Server

    DiBene, Joseph T

    2014-01-01

    An all-encompassing text that focuses on the fundamentals of power integrity Power integrity is the study of power distribution from the source to the load and the system level issues that can occur across it. For computer systems, these issues can range from inside the silicon to across the board and may egress into other parts of the platform, including thermal, EMI, and mechanical. With a focus on computer systems and silicon level power delivery, this book sheds light on the fundamentals of power integrity, utilizing the author's extensive background in the power integrity industry and un

  7. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.

    Science.gov (United States)

    Tamplin, Owen J; Cox, Brian J; Rossant, Janet

    2011-12-15

    The node and notochord are key tissues required for patterning of the vertebrate body plan. Understanding the gene regulatory network that drives their formation and function is therefore important. Foxa2 is a key transcription factor at the top of this genetic hierarchy and finding its targets will help us to better understand node and notochord development. We performed an extensive microarray-based gene expression screen using sorted embryonic notochord cells to identify early notochord-enriched genes. We validated their specificity to the node and notochord by whole mount in situ hybridization. This provides the largest available resource of notochord-expressed genes, and therefore candidate Foxa2 target genes in the notochord. Using existing Foxa2 ChIP-seq data from adult liver, we were able to identify a set of genes expressed in the notochord that had associated regions of Foxa2-bound chromatin. Given that Foxa2 is a pioneer transcription factor, we reasoned that these sites might represent notochord-specific enhancers. Candidate Foxa2-bound regions were tested for notochord specific enhancer function in a zebrafish reporter assay and 7 novel notochord enhancers were identified. Importantly, sequence conservation or predictive models could not have readily identified these regions. Mutation of putative Foxa2 binding elements in two of these novel enhancers abrogated reporter expression and confirmed their Foxa2 dependence. The combination of highly specific gene expression profiling and genome-wide ChIP analysis is a powerful means of understanding developmental pathways, even for small cell populations such as the notochord. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. 76 FR 47114 - Wireless E911 Location Accuracy Requirements; E911 Requirements for IP-Enabled Service Providers

    Science.gov (United States)

    2011-08-04

    .... Power and Associates, indicate that indoor wireless calls have increased dramatically in the past few... Docket No. 05-196; FCC 11-107] Wireless E911 Location Accuracy Requirements; E911 Requirements for IP... transmission is entirely over IP-based networks. By referencing E.164 telephone numbers and eliminating...

  9. Structural safety test and analysis of type IP-2 transport packages with bolted lid type and thick steel plate for radioactive waste drums in a NPP

    International Nuclear Information System (INIS)

    Kim, Dong Hak; Seo, Ki Seog; Lee, Sang Jin; Lee, Kyung Ho; Kim, Jeong Mook

    2007-01-01

    If a type IP-2 transport package were to be subjected to a free drop test and a penetration test under the normal conditions of transport, it should prevent a loss or dispersal of the radioactive contents and a more than 20% increase in the maximum radiation level at any external surface of the package. In this paper, we suggested the analytic method to evaluate the structural safety of a type IP-2 transport package using a thick steel plate for a structure part and a bolt for tying a bolt. Using an analysis a loss or disposal of the radioactive contents and a loss of shielding integrity were confirmed for two kinds of type IP-2 transport packages to transport radioactive waste drums from a waste facility to a temporary storage site in a nuclear power plant. Under the free drop condition the maximum average stress at the bolts and the maximum opening displacement of a lid were compared with the tensile stress of a bolt and the steps in a lid, which were made to avoid a streaming radiation in the shielding path, to evaluate a loss or dispersal of radioactive waste contents. Also a loss of shielding integrity was evaluated using the maximum decrease in a shielding thickness. To verify the impact dynamic analysis for free drop test condition and evaluate experimentally the safety of two kinds of type IP-2 transport packages, free drop tests were conducted with various drop directions

  10. Mobile-ip Aeronautical Network Simulation Study

    Science.gov (United States)

    Ivancic, William D.; Tran, Diepchi T.

    2001-01-01

    NASA is interested in applying mobile Internet protocol (mobile-ip) technologies to its space and aeronautics programs. In particular, mobile-ip will play a major role in the Advanced Aeronautic Transportation Technology (AATT), the Weather Information Communication (WINCOMM), and the Small Aircraft Transportation System (SATS) aeronautics programs. This report presents the results of a simulation study of mobile-ip for an aeronautical network. The study was performed to determine the performance of the transmission control protocol (TCP) in a mobile-ip environment and to gain an understanding of how long delays, handoffs, and noisy channels affect mobile-ip performance.

  11. Self-powered integrated systems-on-chip (energy chip)

    KAUST Repository

    Hussain, Muhammad Mustafa

    2010-04-23

    In today\\'s world, consumer driven technology wants more portable electronic gadgets to be developed, and the next big thing in line is self-powered handheld devices. Therefore to reduce the power consumption as well as to supply sufficient power to run those devices, several critical technical challenges need to be overcome: a. Nanofabrication of macro/micro systems which incorporates the direct benefit of light weight (thus portability), low power consumption, faster response, higher sensitivity and batch production (low cost). b. Integration of advanced nano-materials to meet the performance/cost benefit trend. Nano-materials may offer new functionalities that were previously underutilized in the macro/micro dimension. c. Energy efficiency to reduce power consumption and to supply enough power to meet that low power demand. We present a pragmatic perspective on a self-powered integrated System on Chip (SoC). We envision the integrated device will have two objectives: low power consumption/dissipation and on-chip power generation for implementation into handheld or remote technologies for defense, space, harsh environments and medical applications. This paper provides insight on materials choices, intelligent circuit design, and CMOS compatible integration.

  12. Self-powered integrated systems-on-chip (energy chip)

    Science.gov (United States)

    Hussain, M. M.; Fahad, H.; Rojas, J.; Hasan, M.; Talukdar, A.; Oommen, J.; Mink, J.

    2010-04-01

    In today's world, consumer driven technology wants more portable electronic gadgets to be developed, and the next big thing in line is self-powered handheld devices. Therefore to reduce the power consumption as well as to supply sufficient power to run those devices, several critical technical challenges need to be overcome: a. Nanofabrication of macro/micro systems which incorporates the direct benefit of light weight (thus portability), low power consumption, faster response, higher sensitivity and batch production (low cost). b. Integration of advanced nano-materials to meet the performance/cost benefit trend. Nano-materials may offer new functionalities that were previously underutilized in the macro/micro dimension. c. Energy efficiency to reduce power consumption and to supply enough power to meet that low power demand. We present a pragmatic perspective on a self-powered integrated System on Chip (SoC). We envision the integrated device will have two objectives: low power consumption/dissipation and on-chip power generation for implementation into handheld or remote technologies for defense, space, harsh environments and medical applications. This paper provides insight on materials choices, intelligent circuit design, and CMOS compatible integration.

  13. Adjusting the IP $\\beta$ Functions in RHIC

    CERN Document Server

    Wittmer, W; Pilat, F; Ptitsyn, V; Van Zeijts, J

    2004-01-01

    The beta functions at the IP can be adjusted without perturbation of other optics functions via several approaches. In this paper we describe a scheme based on a vector knob, which assigns fixed values to the different tuning quadrupoles and scales them by a common multiplier. The values for the knob vector were calculated for a lattice without any errors using MADX. Previous studies for the LHC [1] have shown that this approach can meet the design goals. A specific feature of the RHIC lattice is the nested power supply system. To cope with the resulting problems a detailed response matrix analysis has been carried out and different sets of knobs were calculated and compared. The knobs were tested at RHIC during the 2004 run and preliminary results are discussed. Simultaneously a new approach to measure the beam sizes of both colliding beams at the IP, based on the tunability provided by the knobs, was developed and tested.

  14. Subtype-selective regulation of IP(3) receptors by thimerosal via cysteine residues within the IP(3)-binding core and suppressor domain.

    Science.gov (United States)

    Khan, Samir A; Rossi, Ana M; Riley, Andrew M; Potter, Barry V L; Taylor, Colin W

    2013-04-15

    IP(3)R (IP(3) [inositol 1,4,5-trisphosphate] receptors) and ryanodine receptors are the most widely expressed intracellular Ca(2+) channels and both are regulated by thiol reagents. In DT40 cells stably expressing single subtypes of mammalian IP(3)R, low concentrations of thimerosal (also known as thiomersal), which oxidizes thiols to form a thiomercurylethyl complex, increased the sensitivity of IP(3)-evoked Ca(2+) release via IP(3)R1 and IP(3)R2, but inhibited IP(3)R3. Activation of IP(3)R is initiated by IP(3) binding to the IBC (IP(3)-binding core; residues 224-604) and proceeds via re-arrangement of an interface between the IBC and SD (suppressor domain; residues 1-223). Thimerosal (100 μM) stimulated IP(3) binding to the isolated NT (N-terminal; residues 1-604) of IP(3)R1 and IP(3)R2, but not to that of IP(3)R3. Binding of a competitive antagonist (heparin) or partial agonist (dimeric-IP(3)) to NT1 was unaffected by thiomersal, suggesting that the effect of thimerosal is specifically related to IP(3)R activation. IP(3) binding to NT1 in which all cysteine residues were replaced by alanine was insensitive to thimerosal, so too were NT1 in which cysteine residues were replaced in either the SD or IBC. This demonstrates that thimerosal interacts directly with cysteine in both the SD and IBC. Chimaeric proteins in which the SD of the IP(3)R was replaced by the structurally related A domain of a ryanodine receptor were functional, but thimerosal inhibited both IP(3) binding to the chimaeric NT and IP(3)-evoked Ca(2+) release from the chimaeric IP(3)R. This is the first systematic analysis of the effects of a thiol reagent on each IP(3)R subtype. We conclude that thimerosal selectively sensitizes IP(3)R1 and IP(3)R2 to IP(3) by modifying cysteine residues within both the SD and IBC and thereby stabilizing an active conformation of the receptor.

  15. Subtype-selective regulation of IP3 receptors by thimerosal via cysteine residues within the IP3-binding core and suppressor domain

    Science.gov (United States)

    Khan, Samir A.; Rossi, Ana M.; Riley, Andrew M.; Potter, Barry V. L.; Taylor, Colin W.

    2013-01-01

    IP3R (IP3 [inositol 1,4,5-trisphosphate] receptors) and ryanodine receptors are the most widely expressed intracellular Ca2+ channels and both are regulated by thiol reagents. In DT40 cells stably expressing single subtypes of mammalian IP3R, low concentrations of thimerosal (also known as thiomersal), which oxidizes thiols to form a thiomercurylethyl complex, increased the sensitivity of IP3-evoked Ca2+ release via IP3R1 and IP3R2, but inhibited IP3R3. Activation of IP3R is initiated by IP3 binding to the IBC (IP3-binding core; residues 224–604) and proceeds via re-arrangement of an interface between the IBC and SD (suppressor domain; residues 1–223). Thimerosal (100 μM) stimulated IP3 binding to the isolated NT (N-terminal; residues 1–604) of IP3R1 and IP3R2, but not to that of IP3R3. Binding of a competitive antagonist (heparin) or partial agonist (dimeric-IP3) to NT1 was unaffected by thiomersal, suggesting that the effect of thimerosal is specifically related to IP3R activation. IP3 binding to NT1 in which all cysteine residues were replaced by alanine was insensitive to thimerosal, so too were NT1 in which cysteine residues were replaced in either the SD or IBC. This demonstrates that thimerosal interacts directly with cysteine in both the SD and IBC. Chimaeric proteins in which the SD of the IP3R was replaced by the structurally related A domain of a ryanodine receptor were functional, but thimerosal inhibited both IP3 binding to the chimaeric NT and IP3-evoked Ca2+ release from the chimaeric IP3R. This is the first systematic analysis of the effects of a thiol reagent on each IP3R subtype. We conclude that thimerosal selectively sensitizes IP3R1 and IP3R2 to IP3 by modifying cysteine residues within both the SD and IBC and thereby stabilizing an active conformation of the receptor. PMID:23282150

  16. Scheduling of Power System Cells Integrating Stochastic Power Generation

    International Nuclear Information System (INIS)

    Costa, L.M.

    2008-12-01

    Energy supply and climate change are nowadays two of the most outstanding problems which societies have to cope with under a context of increasing energy needs. Public awareness of these problems is driving political willingness to take actions for tackling them in a swift and efficient manner. Such actions mainly focus in increasing energy efficiency, in decreasing dependence on fossil fuels, and in reducing greenhouse gas emissions. In this context, power systems are undergoing important changes in the way they are planned and managed. On the one hand, vertically integrated structures are being replaced by market structures in which power systems are un-bundled. On the other, power systems that once relied on large power generation facilities are witnessing the end of these facilities' life-cycle and, consequently, their decommissioning. The role of distributed energy resources such as wind and solar power generators is becoming increasingly important in this context. However, the large-scale integration of such type of generation presents many challenges due, for instance, to the uncertainty associated to the variability of their production. Nevertheless, advanced forecasting tools may be combined with more controllable elements such as energy storage devices, gas turbines, and controllable loads to form systems that aim to reduce the impacts that may be caused by these uncertainties. This thesis addresses the management under market conditions of these types of systems that act like independent societies and which are herewith named power system cells. From the available literature, a unified view of power system scheduling problems is also proposed as a first step for managing sets of power system cells in a multi-cell management framework. Then, methodologies for performing the optimal day-ahead scheduling of single power system cells are proposed, discussed and evaluated under both a deterministic and a stochastic framework that directly integrates the

  17. Research Developments on Power System Integration of Wind Power

    DEFF Research Database (Denmark)

    Chen, Zhe; Hansen, Jens Carsten; Wu, Qiuwei

    2011-01-01

    variability and prediction, wind power plant ancillary services, grid connection and operation, Smart grids and demand side management under market functionality. The topics of the first group of PhD program starting 2011 under the wind energy Sino-Danish Centre for Education & Research (SDC) are also......This paper presents an overview on the recent research activities and tendencies regarding grid integration of wind power in Denmark and some related European activities, including power electronics for enhancing wind power controllability, wind turbines and wind farms modeling, wind power...

  18. Applying a gaming approach to IP strategy.

    Science.gov (United States)

    Gasnier, Arnaud; Vandamme, Luc

    2010-02-01

    Adopting an appropriate IP strategy is an important but complex area, particularly in the pharmaceutical and biotechnology sectors, in which aspects such as regulatory submissions, high competitive activity, and public health and safety information requirements limit the amount of information that can be protected effectively through secrecy. As a result, and considering the existing time limits for patent protection, decisions on how to approach IP in these sectors must be made with knowledge of the options and consequences of IP positioning. Because of the specialized nature of IP, it is necessary to impart knowledge regarding the options and impact of IP to decision-makers, whether at the level of inventors, marketers or strategic business managers. This feature review provides some insight on IP strategy, with a focus on the use of a new 'gaming' approach for transferring the skills and understanding needed to make informed IP-related decisions; the game Patentopolis is discussed as an example of such an approach. Patentopolis involves interactive activities with IP-related business decisions, including the exploitation and enforcement of IP rights, and can be used to gain knowledge on the impact of adopting different IP strategies.

  19. PolyaPeak: Detecting Transcription Factor Binding Sites from ChIP-seq Using Peak Shape Information

    Science.gov (United States)

    Wu, Hao; Ji, Hongkai

    2014-01-01

    ChIP-seq is a powerful technology for detecting genomic regions where a protein of interest interacts with DNA. ChIP-seq data for mapping transcription factor binding sites (TFBSs) have a characteristic pattern: around each binding site, sequence reads aligned to the forward and reverse strands of the reference genome form two separate peaks shifted away from each other, and the true binding site is located in between these two peaks. While it has been shown previously that the accuracy and resolution of binding site detection can be improved by modeling the pattern, efficient methods are unavailable to fully utilize that information in TFBS detection procedure. We present PolyaPeak, a new method to improve TFBS detection by incorporating the peak shape information. PolyaPeak describes peak shapes using a flexible Pólya model. The shapes are automatically learnt from the data using Minorization-Maximization (MM) algorithm, then integrated with the read count information via a hierarchical model to distinguish true binding sites from background noises. Extensive real data analyses show that PolyaPeak is capable of robustly improving TFBS detection compared with existing methods. An R package is freely available. PMID:24608116

  20. Generation of an iPS cell line via a non-integrative method using urine-derived cells from a patient with USH2A-associated retinitis pigmentosa

    Directory of Open Access Journals (Sweden)

    Yonglong Guo

    2018-05-01

    Full Text Available We have established an induced pluripotent stem (iPS cell line using urine-derived cells from a 27-year-old male patient with retinitis pigmentosa associated with point mutations in the USH2A gene. Feeder-free culture conditions and the integration-free CytoTune™-iPS 2.0 Sendai Reprogramming Kit were used.

  1. Integrated Wind Power Planning Tool

    DEFF Research Database (Denmark)

    Rosgaard, M. H.; Hahmann, Andrea N.; Nielsen, T. S.

    This poster describes the status as of April 2012 of the Public Service Obligation (PSO) funded project PSO 10464 \\Integrated Wind Power Planning Tool". The project goal is to integrate a meso scale numerical weather prediction (NWP) model with a statistical tool in order to better predict short...... term power variation from off shore wind farms, as well as to conduct forecast error assessment studies in preparation for later implementation of such a feature in an existing simulation model. The addition of a forecast error estimation feature will further increase the value of this tool, as it...

  2. Extending Tactical Fleet Communications Through VoIP

    Science.gov (United States)

    2014-09-01

    corporate world , the military is leveraging VoIP communication solutions as well. Shore commands like Tactical Training Group Pacific use VoIP for...VoIP fuzzing (e.g., Asteroid , PROTOS, Sip-Proxy)  VoIP signaling manipulation (e.g., IAXAuthJack, IAXHangup, SIP-Kill)  VoIP media...as well, but instead of just matching the information to rules, it compares synchronization information between the protocols to determine if the

  3. Hardware IP security and trust

    CERN Document Server

    Bhunia, Swarup; Tehranipoor, Mark

    2017-01-01

    This book provides an overview of current Intellectual Property (IP) based System-on-Chip (SoC) design methodology and highlights how security of IP can be compromised at various stages in the overall SoC design-fabrication-deployment cycle. Readers will gain a comprehensive understanding of the security vulnerabilities of different types of IPs. This book would enable readers to overcome these vulnerabilities through an efficient combination of proactive countermeasures and design-for-security solutions, as well as a wide variety of IP security and trust assessment and validation techniques. This book serves as a single-source of reference for system designers and practitioners for designing secure, reliable and trustworthy SoCs.

  4. Presence in the IP multimedia subsystem

    NARCIS (Netherlands)

    Lin, L.; Liotta, A.

    2007-01-01

    With an ever increasing penetration of Internet Protocol (IP) technologies, the wireless industry is evolving the mobile core network towards all-IP network. The IP Multimedia Subsystem (IMS) is a standardised Next Generation Network (NGN) architectural framework defined by the 3rd Generation

  5. Power System Operation with Large Scale Wind Power Integration

    DEFF Research Database (Denmark)

    Suwannarat, A.; Bak-Jensen, B.; Chen, Z.

    2007-01-01

    to the uncertain nature of wind power. In this paper, proposed models of generations and control system are presented which analyze the deviation of power exchange at the western Danish-German border, taking into account the fluctuating nature of wind power. The performance of the secondary control of the thermal......The Danish power system starts to face problems of integrating thousands megawatts of wind power, which produce in a stochastic behavior due to natural wind fluctuations. With wind power capacities increasing, the Danish Transmission System Operator (TSO) is faced with new challenges related...... power plants and the spinning reserves control from the Combined Heat and Power (CHP) units to achieve active power balance with the increased wind power penetration is presented....

  6. Performance of VoIP on HSDPA

    DEFF Research Database (Denmark)

    Wang, Bang; Pedersen, Klaus I.; Kolding, Troels E.

    2005-01-01

    This paper provides packet scheduler design and performance simulations for running VoIP services over high-speed downlink packet access (HSDPA) in WCDMA. The main challenge of supporting VoIP service on HSDPA is the tight delay requirement combined with the small VoIP packet size. A packet...... scheduler design incorporating VoIP packet aggregation and user multiplexing is proposed and the VoIP capacity is studied for a macro-cellular environment. Results are obtained for different delay budgets and packet scheduling settings, using either blind round robin or a slightly modified version...... of proportional fair scheduling. For proportional fair scheduling with code-multiplexing of 4-users, the downlink VoIP cell capacity on HSDPA is found to be in the range 72-104 users depending on whether the delay budget for the Node-B scheduling and user reception equals 80 ms or 150 ms, respectively....

  7. Practical Integration-Free Episomal Methods for Generating Human Induced Pluripotent Stem Cells.

    Science.gov (United States)

    Kime, Cody; Rand, Tim A; Ivey, Kathryn N; Srivastava, Deepak; Yamanaka, Shinya; Tomoda, Kiichiro

    2015-10-06

    The advent of induced pluripotent stem (iPS) cell technology has revolutionized biomedicine and basic research by yielding cells with embryonic stem (ES) cell-like properties. The use of iPS-derived cells for cell-based therapies and modeling of human disease holds great potential. While the initial description of iPS cells involved overexpression of four transcription factors via viral vectors that integrated within genomic DNA, advances in recent years by our group and others have led to safer and higher quality iPS cells with greater efficiency. Here, we describe commonly practiced methods for non-integrating induced pluripotent stem cell generation using nucleofection of episomal reprogramming plasmids. These methods are adapted from recent studies that demonstrate increased hiPS cell reprogramming efficacy with the application of three powerful episomal hiPS cell reprogramming factor vectors and the inclusion of an accessory vector expressing EBNA1. Copyright © 2015 John Wiley & Sons, Inc.

  8. Measuring the impostor phenomenon: a comparison of Clance's IP Scale and Harvey's I-P Scale.

    Science.gov (United States)

    Holmes, S W; Kertay, L; Adamson, L B; Holland, C L; Clance, P R

    1993-02-01

    Many of the discrepancies reported to date in empirical investigations of the impostor phenomenon (IP) may be due in part to (a) the use of different methods for identifying individuals suffering from this syndrome (impostors), (b) the common use of a median split procedure to classify subjects and (c) the fact that subjects in many studies were drawn from impostor-prone samples. In this study, we compared the scores of independently identified impostors and nonimpostors on two instruments designed to measure the IP: Harvey's I-P Scale and Clance's IP Scale. The results suggest that Clance's scale may be the more sensitive and reliable instrument. Cutoff score suggestions for both instruments are offered.

  9. A comparison of the microstructure and properties of the IPS Empress 2 and the IPS Empress glass-ceramics.

    Science.gov (United States)

    Höland, W; Schweiger, M; Frank, M; Rheinberger, V

    2000-01-01

    The aim of this report is to analyze the microstructures of glass-ceramics of the IPS Empress 2 and IPS Empress systems by scanning electron microscopy. The main properties of the glass-ceramics were determined and compared to each other. The flexural strength of the pressed glass-ceramic (core material) was improved by a factor of more than three for IPS Empress 2 (lithium disilicate glass-ceramic) in comparison with IPS Empress (leucite glass-ceramic). For the fracture toughness, the K(IC) value was measured as 3.3 +/- 0.3 MPa. m(0.5) for IPS Empress 2 and 1.3 +/- 0.1 MPa. m(0.5) for IPS Empress. Abrasion behavior, chemical durability, and optical properties such as translucency of all glass-ceramics fulfill the dental standards. The authors concluded that IPS Empress 2 can be used to fabricate 3-unit bridges up to the second premolar. Copyright 2000 John Wiley & Sons, Inc.

  10. Integrating Photovoltaic Systems in Power System: Power Quality Impacts and Optimal Planning Challenges

    Directory of Open Access Journals (Sweden)

    Aida Fazliana Abdul Kadir

    2014-01-01

    Full Text Available This paper is an overview of some of the main issues in photovoltaic based distributed generation (PVDG. A discussion of the harmonic distortion produced by PVDG units is presented. The maximum permissible penetration level of PVDG in distribution system is also considered. The general procedures of optimal planning for PVDG placement and sizing are also explained in this paper. The result of this review shows that there are different challenges for integrating PVDG in the power systems. One of these challenges is integrated system reliability whereas the amount of power produced by renewable energy source is consistent. Thus, the high penetration of PVDG into grid can decrease the reliability of the power system network. On the other hand, power quality is considered one of the challenges of PVDG whereas the high penetration of PVDGs can lead to more harmonic propagation into the power system network. In addition to that, voltage fluctuation of the integrated PVDG and reverse power flow are two important challenges to this technology. Finally, protection of power system with integrated PVDG is one of the most critical challenges to this technology as the current protection schemes are designed for unidirectional not bidirectional power flow pattern.

  11. Overcoming communication challenges in integrative supportive cancer care: The integrative physician, the psycho-oncologist, and the patient.

    Science.gov (United States)

    Ben-Arye, Eran; Shavit, Efrat; Wiental, Haya; Schiff, Elad; Agour, Olga; Samuels, Noah

    2016-12-01

    Complementary/integrative medicine (CIM) services are increasingly being integrated into conventional supportive cancer care, presenting a number of challenges to communication between healthcare professionals (HCPs). The purpose of the present study was to explore the impact of the communication between integrative physicians (IPs) trained in CIM and social workers (SWs) working as psycho-oncologists in the same oncology setting. We examine whether IP-SW communication correlates with the number of patient-SW sessions, as provided within the oncology department. SW-IP communication, defined as a summary of the IP consultation sent to the patient's SW, was compared to SW-patient communication, defined as the number of psycho-oncology treatment sessions. Of 344 patients referred by their oncology HCP for IP consultation, 91 were referred by an SW and 253 by an oncologist or nurse. IP-to-SW summaries were provided for 150 patients referred by a non-SW HCP (43.6%), and for 91 of SW-referred patients (26.5%). In all, 32 patients referred to the IP had no psycho-oncology interaction with an SW; 58 only one meeting; and 254 with ≥2 interactions, with 119 having >6 sessions. SW-patient interactions were greater with higher rates of IP-SW communication, for both patients referred by an SW (79.1%) and those referred by a non-SW HCP (77.3%) when compared to patients for whom no summary was provided (64.1%; p= 0.02). A greater level of IP-SW communication, measured by the provision of an IP summary to the patient's SW, was found to correlate with a higher rate of SW-patient interactions. The use of a structured two-way referral-summary between IPs and SWs has the potential to advance the SW-patient psycho-oncology interaction, within an integrative supportive cancer care setting. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Outbreak of Ips nitidus and Ips shangrila in northeastern margin of the Tibetan Plateau

    Czech Academy of Sciences Publication Activity Database

    Jakuš, R.; Kalinová, Blanka; Hoskovec, Michal; Knížek, M.; Schlyter, F.; Sun, J.-H.; Zhang, Q. H.

    2011-01-01

    Roč. 89, - (2011), s. 111-117 ISSN 1436-1566 R&D Projects: GA MŠk ME 860 Institutional research plan: CEZ:AV0Z40550506 Keywords : Ips shangrila * Ips nitidus * pheromone s * GCxGC-TOFMS Subject RIV: CC - Organic Chemistry

  13. PENGEMBANGAN PERANGKAT PEMBELAJARAN IPS TERPADU BERBASIS OUTDOOR LEARNING

    Directory of Open Access Journals (Sweden)

    Nugraheni Rachmawati

    2013-03-01

    Full Text Available AbstrakPelaksanaan kegiatan pembelajaran tematik di SD kota Semarang belum optimal. Sebagian besar guru belum menyusun dan menggunakan perangkat pembelaja- ran IPS Terpadu berbasis outdoor learning. Tujuan penelitian ini mengembangkan, mengkaji keefektifan dan kepraktisan perangkat pembelajaran. Penelitian ini meru- pakan penelitian pengembangan yang dimodifikasi dari penelitian Borg and Gall. Subjek penelitian adalah siswa kelas 3 SD N Jatingaleh 01-02 Kota Semarang ta- hun pelajaran 2012/2013. Spesifikasi produk yang dikembangkan adalah perangkat pembelajaran IPS terpadu berbasis outdoor learning berupa silabus, RPP, media CD Interaktif, LKS dan alat evaluasi meliputi test kognitif, lembar observasi aktivi- tas serta angket respons siswa dan guru. Data dianalisis secara deskriptif dan Pretest- Posttest Control Group Design. Hasil penelitian menunjukkan bahwa pengembangan perangkat pembelajaran tergolong valid. Keefektifan perangkat dilihat dari aktivitas dan hasil belajar siswa. Aktivitas siswa tergolong sangat tinggi. Hasil belajar kog- nitif siswa setelah mengikuti pembelajaran IPS Terpadu berbasis Outdoor Learning mengalami peningkatan yang signifikan serta mencapai ketuntasan belajar. Rata- rata hasil belajar kognitif siswa secara signifikan lebih besar daripada kelompok siswa yang mengikuti pembelajaran in door. Saran, hendaknya dapat dikembangkan lagi keefektifanya sehingga dapat lebih menggali kemampuan siswa, tidak hanya dalam segi kognitif dan afektif tetapi juga psikomotor. AbstractImplementation of thematic learning activities in elementary school of Semarang is not opti- mal. Most of the teachers do not prepare and use integrated social science learning tools based on outdoor learning. This research is aimed to develop the tools and to review the effectiveness and practicality of integrated social science learning based on outdoor learning. This is a research and development study modified from the research developed by Borg and

  14. Integral Indicator of Ecological Footprint for Croatian Power Plants

    International Nuclear Information System (INIS)

    Strijov, V.; Granic, G.; Juric, Z.; Jelavic, B.; Antesevic Maricic, S.

    2009-01-01

    The main goal of this paper is to present the methodology of construction of the Integral Indicator for Croatian Thermal Power Plants and Combined Heat and Power Plants. The Integral Indicator is necessary to compare Power Plants selected according to a certain criterion. The criterion of the Ecological Footprint is chosen. The following features of the Power Plants are used: generated electricity and heat; consumed coal and liquid fuel; sulphur content in fuel; emitted CO 2 , SO 2 , NO x and particles. To construct the Integral Indicator the linear model is used. The model parameters are tuned by the Principal Component Analysis algorithm. The constructed Integral Indicator is compared with several others, such as Pareto-Optimal Slicing Indicator and Metric Indicator. The Integral Indicator keeps as much information about features of the Power Plants as possible; it is simple and robust.(author).

  15. Voice over IP in Wireless Heterogeneous Networks

    DEFF Research Database (Denmark)

    Fathi, Hanane; Chakraborty, Shyam; Prasad, Ramjee

    with the deployment of wireless heterogeneous systems, both speech and data traffic are carrried over wireless links by the same IP-based packet-switched infrastructure. However, this combination faces some challenges due to the inherent properties of the wireless network. The requirements for good quality VoIP...... communications are difficult to achieve in a time-varying environment due to channel errors and traffic congestion and across different systems. The provision of VoIP in wireless heterogeneous networks requires a set of time-efficient control mechanisms to support a VoIP session with acceptable quality....... The focus of Voice over IP in Wierless Heterogeneous Networks is on mechanisms that affect the VoIP user satisfaction  while not explicitly involved in the media session. This relates to the extra delays introduced by the security and the signaling protocols used to set up an authorized VoIP session...

  16. TradeWind. Integrating wind. Developing Europe's power market for the large-scale integration of wind power. Final report

    Energy Technology Data Exchange (ETDEWEB)

    2009-02-15

    Based on a single European grid and power market system, the TradeWind project explores to what extent large-scale wind power integration challenges could be addressed by reinforcing interconnections between Member States in Europe. Additionally, the project looks at the conditions required for a sound power market design that ensures a cost-effective integration of wind power at EU level. In this way, the study addresses two issues of key importance for the future integration of renewable energy, namely the weak interconnectivity levels between control zones and the inflexibility and fragmented nature of the European power market. Work on critical transmission paths and interconnectors is slow for a variety of reasons including planning and administrative barriers, lack of public acceptance, insufficient economic incentives for TSOs, and the lack of a joint European approach by the key stakeholders. (au)

  17. PowerCube: Integrated Power, Propulsion, and Pointing for CubeSats, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Tethers Unlimited, Inc. proposes to develop the PowerCube, an integrated power, propulsion, and pointing solution for CubeSats. The PowerCube combines three...

  18. Review of Integration of Distributed Energy Resources (DERs) into Power Systems

    DEFF Research Database (Denmark)

    Wu, Qiuwei; Xu, Zhao

    2011-01-01

    state‐of‐the‐art DER integration concepts  relations existing DER integration concepts to the EV system The power balancing challenges of power systems brought by high penetration of intermittent DER have been discussed, especially the wind power integration in the Danish context. The relevance...... of the integration of electric vehicles (EVs) to the DER integration concepts have been analyzed as well based on the energy storage potential of EVs.   Two main concepts for DER integration, virtual power plant (VPP) and microgrids, are described and a comparison of the two concepts have been done. The comparison......An overview of the integration of distributed energy resources (DER) into power systems has been presented in this report. Different aspects of integration of DER into power systems have been reviewed and discussed which are listed below.    needs of DER integration into power systems  various...

  19. Lateral power transistors in integrated circuits

    CERN Document Server

    Erlbacher, Tobias

    2014-01-01

    This book details and compares recent advancements in the development of novel lateral power transistors (LDMOS devices) for integrated circuits in power electronic applications. It includes the state-of-the-art concept of double-acting RESURF topologies.

  20. DNA end resection by CtIP and exonuclease 1 prevents genomic instability

    DEFF Research Database (Denmark)

    Eid, Wassim; Steger, Martin; El-Shemerly, Mahmoud

    2010-01-01

    End resection of DNA-which is essential for the repair of DNA double-strand breaks (DSBs) by homologous recombination-relies first on the partnership between MRE11-RAD50-NBS1 (MRN) and CtIP, followed by a processive step involving helicases and exonucleases such as exonuclease 1 (EXO1). In this s......End resection of DNA-which is essential for the repair of DNA double-strand breaks (DSBs) by homologous recombination-relies first on the partnership between MRE11-RAD50-NBS1 (MRN) and CtIP, followed by a processive step involving helicases and exonucleases such as exonuclease 1 (EXO1...... of DNA-PK-dependent radial chromosome formation. Thus, our study identifies new functions of CtIP and EXO1 in DNA end resection and provides new information on the regulation of DSB repair pathways, which is a key factor in the maintenance of genome integrity....

  1. National strategy of nuclear power intellectual property

    International Nuclear Information System (INIS)

    Bo Huaitao

    2008-01-01

    The IP strategy includes four strategic levels: international level, national level, industry level and enterprise level. The national nuclear power IP strategy is an industry level strategy, which is also one part of national IP strategy, permeating with the IP strategy of the international level and enterprise level mutually. Commencing from the angles of the national level and the industry level, the author tries to provide a reference for IP strategy by an initial study about IP strategy in nuclear power industry.. The author holds that independent innovation is at the root of strategic establishment; enterprise is the main body for strategic implementation; and evaluating index must be consummated in the strategic evaluation. (authors)

  2. Smart Power: New power integrated circuit technologies and their applications

    Science.gov (United States)

    Kuivalainen, Pekka; Pohjonen, Helena; Yli-Pietilae, Timo; Lenkkeri, Jaakko

    1992-05-01

    Power Integrated Circuits (PIC) is one of the most rapidly growing branches of the semiconductor technology. The PIC markets has been forecast to grow from 660 million dollars in 1990 to 1658 million dollars in 1994. It has even been forecast that at the end of the 1990's the PIC markets would correspond to the value of the whole semiconductor production in 1990. Automotive electronics will play the leading role in the development of the standard PIC's. Integrated motor drivers (36 V/4 A), smart integrated switches (60 V/30 A), solenoid drivers, integrated switch-mode power supplies and regulators are the latest standard devices of the PIC manufactures. ASIC (Application Specific Integrated Circuits) PIC solutions are needed for the same reasons as other ASIC devices: there are no proper standard devices, a company has a lot of application knowhow, which should be kept inside the company, the size of the product must be reduced, and assembly costs are wished to be reduced by decreasing the number of discrete devices. During the next few years the most probable ASIC PIC applications in Finland will be integrated solenoid and motor drivers, an integrated electronic lamp ballast circuit and various sensor interface circuits. Application of the PIC technologies to machines and actuators will strongly be increased all over the world. This means that various PIC's, either standard PIC's or full custom ASIC circuits, will appear in many products which compete with the corresponding Finnish products. Therefore the development of the PIC technologies must be followed carefully in order to immediately be able to apply the latest development in the smart power technologies and their design methods.

  3. Innovative use of power integrated modules for DC power supplies

    DEFF Research Database (Denmark)

    Ørndrup Nielsen, Rasmus; Elkiær, Alexander; Munk-Nielsen, Stig

    2013-01-01

    In this article several innovative ways of utilizing Power Integrated Modules (PIM) as switching device in a DC power supply are presented. PIM have advantages in compactness of design, cost and fast prototype due to easier PCB layout. A PIM converter topology is chosen and designed resulting...... in an experimental setup. Results from the setup are presented showing the feasibility of using a PIM module as almost all power semiconductors in a DC power supply....

  4. Electric Vehicle Integration into Modern Power Networks

    DEFF Research Database (Denmark)

    software tools to assess the impacts resulting from the electric vehicles deployment on the steady state and dynamic operation of electricity grids, identifies strategies to mitigate them and the possibility to support simultaneously large-scale integration of renewable energy sources. New business models......Electric Vehicle Integration into Modern Power Networks provides coverage of the challenges and opportunities posed by the progressive integration of electric drive vehicles. Starting with a thorough overview of the current electric vehicle and battery state-of-the-art, this work describes dynamic...... and control management architectures, as well as the communication infrastructure required to integrate electric vehicles as active demand are presented. Finally, regulatory issues of integrating electric vehicles into modern power systems are addressed. Inspired by two courses held under the EES...

  5. Electric Vehicle Integration into Modern Power Networks

    DEFF Research Database (Denmark)

    Electric Vehicle Integration into Modern Power Networks provides coverage of the challenges and opportunities posed by the progressive integration of electric drive vehicles. Starting with a thorough overview of the current electric vehicle and battery state-of-the-art, this work describes dynamic...... software tools to assess the impacts resulting from the electric vehicles deployment on the steady state and dynamic operation of electricity grids, identifies strategies to mitigate them and the possibility to support simultaneously large-scale integration of renewable energy sources. New business models...... and control management architectures, as well as the communication infrastructure required to integrate electric vehicles as active demand are presented. Finally, regulatory issues of integrating electric vehicles into modern power systems are addressed. Inspired by two courses held under the EES...

  6. 77 FR 33227 - Assessment Questionnaire-IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT)

    Science.gov (United States)

    2012-06-05

    ... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2011-0069] Assessment Questionnaire--IP Sector... comments concerning new Information Collection Request--Assessment Questionnaire--IP Sector Specific Agency... http://www.regulations.gov , including any personal information provided. OMB is particularly...

  7. 76 FR 48159 - Integrated System Power Rates

    Science.gov (United States)

    2011-08-08

    ... DEPARTMENT OF ENERGY Southwestern Power Administration Integrated System Power Rates AGENCY... American Electric Reliability Corporation and to cover increased investments and replacements in..., prepared a Current Power Repayment Study using existing system rates. The Study indicates that Southwestern...

  8. A summary of impacts of wind power integration on power system small-signal stability

    Science.gov (United States)

    Yan, Lei; Wang, Kewen

    2017-05-01

    Wind power has been increasingly integrated into power systems over the last few decades because of the global energy crisis and the pressure on environmental protection, and the stability of the system connected with wind power is becoming more prominent. This paper summaries the research status, achievements as well as deficiencies of the research on the impact of wind power integration on power system small-signal stability. In the end, the further research needed are discussed.

  9. IP Connected Low Power Wireless Personal Area Networks in the Future Internet

    DEFF Research Database (Denmark)

    Jacobsen, Rune Hylsberg; Toftegaard, Thomas Skjødeberg; Kjærgaard, Jens Kristian

    2012-01-01

    The Internet of Things is a key concept of the Future Internet. The Internet of Things potentially interconnects billions of small devices in a large ubiquitous infrastructure based on the Internet Protocol (IP). Typically, these devices will be limited in computational capacity, memory......WPANs). The authors address the key mechanisms from network aspects down to device design aspects and discuss how technologies interplay to make real application deployment practical for the Internet of Things....

  10. System and market integration of wind power in Denmark

    DEFF Research Database (Denmark)

    Lund, Henrik; Hvelplund, Frede; Alberg Østergaard, Poul

    2013-01-01

    Denmark has more than 10 years’ of experience with a wind share of approximately 20 per cent. During these 10 years, electricity markets have been subject to developments with a key focus on integrating wind power as well as trading electricity with neighbouring countries. This article introduces...... a methodology to analyse and understand the current market integration of wind power and concludes that the majority of Danish wind power in the period 2004e2008 was used to meet the domestic demand. Based on a physical analysis, at least 63 per cent of Danish wind power was used domestically in 2008....... To analyse the remaining 37 per cent, we must apply a market model to identify cause-effect relationships. The Danish case does not illustrate any upper limit for wind power integration, as also illustrated by Danish political targets to integrate 50 per cent by 2020. In recent years, Danish wind power has...

  11. Dynamic energy management employing renewable energy sources in IP over DWDM networks

    DEFF Research Database (Denmark)

    Chen, Xin; Phillips, Chris; Wang, Jiayuan

    2013-01-01

    management framework employing renewable energy sources in IP over DWDM core networks. The main concept is to combine infrastructure sleeping and virtual router migration to improve the network energy efficiency. By using the energy source information provided by the smart grid, the nodes that are powered...

  12. Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function.

    Science.gov (United States)

    Scherer, Paul C; Ding, Yan; Liu, Zhiqing; Xu, Jing; Mao, Haibin; Barrow, James C; Wei, Ning; Zheng, Ning; Snyder, Solomon H; Rao, Feng

    2016-03-29

    The family of cullin-RING E3 Ligases (CRLs) and the constitutive photomorphogenesis 9 (COP9) signalosome (CSN) form dynamic complexes that mediate ubiquitylation of 20% of the proteome, yet regulation of their assembly/disassembly remains poorly understood. Inositol polyphosphates are highly conserved signaling molecules implicated in diverse cellular processes. We now report that inositol hexakisphosphate (IP6) is a major physiologic determinant of the CRL-CSN interface, which includes a hitherto unidentified electrostatic interaction between the N-terminal acidic tail of CSN subunit 2 (CSN2) and a conserved basic canyon on cullins. IP6, with an EC50 of 20 nM, acts as an intermolecular "glue," increasing cullin-CSN2 binding affinity by 30-fold, thereby promoting assembly of the inactive CRL-CSN complexes. The IP6 synthase, Ins(1,3,4,5,6)P5 2-kinase (IPPK/IP5K) binds to cullins. Depleting IP5K increases the percentage of neddylated, active Cul1 and Cul4A, and decreases levels of the Cul1/4A substrates p27 and p21. Besides dysregulating CRL-mediated cell proliferation and UV-induced apoptosis, IP5K depletion potentiates by 28-fold the cytotoxic effect of the neddylation inhibitor MLN4924. Thus, IP5K and IP6 are evolutionarily conserved components of the CRL-CSN system and are potential targets for cancer therapy in conjunction with MLN4924.

  13. Integrated Power, Avionics, and Software (IPAS) Flexible Systems Integration

    Data.gov (United States)

    National Aeronautics and Space Administration — The Integrated Power, Avionics, and Software (IPAS) facility is a flexible, multi-mission hardware and software design environment. This project will develop a...

  14. IPS Empress: a standard of excellence.

    Science.gov (United States)

    Hornbrook, D S; Roberts, M

    1998-01-01

    For 10 years, clinicians have been able to provide patients with a proven aesthetic and functional restoration that exhibits wear-compatibility, durability, and marginal integrity. This leucite-reinforced, pressed ceramic (IPS Empress, Ivoclar Williams, Amherst, NY) presents to patients and dentists the option of a metal-free alternative which retains the functional advantages of a porcelain-fused-to-metal restoration. This article illustrates the importance of sound laboratory communication in the utilization of this restorative material, focusing upon three aspects: midline and incisal edge inclination, elimination of open gingival embrasures, and incisal edge translucency. Techniques are also presented in order to efficiently communicate details of each case presented to the laboratory.

  15. IP Security für Linux

    OpenAIRE

    Parthey, Mirko

    2001-01-01

    Die Nutzung des Internet für sicherheitskritische Anwendungen erfordert kryptographische Schutzmechanismen. IP Security (IPsec) definiert dafür geeignete Protokolle. Diese Arbeit gibt einen Überblick über IPsec. Eine IPsec-Implementierung für Linux (FreeS/WAN) wird auf Erweiterbarkeit und Praxistauglichkeit untersucht. Using the Internet in security-critical areas requires cryptographic protection, for which IP Security (IPsec) defines suitable protocols. This paper gives an overview of IP...

  16. Design and development of FPGA based TCP/IP module for real time computers in nuclear power plants

    International Nuclear Information System (INIS)

    Balasri, G. Janani; Santhana Raj, A.; Gour, Aditya; Murali, N.; Manikandan, J.

    2013-01-01

    An VME (Virtual Module Europa) bus based Real Time Computer's (RTC's) are being developed for Prototype Fast Breeder Reactor (PFBR) which is in an advanced stage of construction at Kalpakkam, where the RTC's have to communicate to the central process computer on the data collected from the field instrument and receive data from the central process computer. A Distributed Digital Control System (DDSC) architecture has been designed for this communication which is based on Transfer Communication Protocol/Internet Protocol (TCP/IP) over Ethernet. Currently the RTC's uses 'Wiznet Module', a bought out chip which implements the TCP/IP stack in hardware. This project concentrates on the design and development of Field Programmable Gate Array (FPGA) based TCP/IP module that runs on Microblaze, a 32-bit softcore processor, to take care of the communication as that of Wiznet module. Advantage of switching over to FPGA based system are its reconfigurability, desired number of sockets, and the design is stable even if the FPGA's get obsolete. (author)

  17. Design and Evaluation of IP Header Compression for Cellular-Controlled P2P Networks

    DEFF Research Database (Denmark)

    Madsen, T.K.; Zhang, Qi; Fitzek, F.H.P.

    2007-01-01

    In this paper we advocate to exploit terminal cooperation to stabilize IP communication using header compression. The terminal cooperation is based on direct communication between terminals using short range communication and simultaneously being connected to the cellular service access point....... The short range link is than used to provide first aid information to heal the decompressor state of the neighboring node in case of a packet loss on the cellular link. IP header compression schemes are used to increase the spectral and power efficiency loosing robustness of the communication compared...

  18. Study on improved Ip-iq APF control algorithm and its application in micro grid

    Science.gov (United States)

    Xie, Xifeng; Shi, Hua; Deng, Haiyingv

    2018-01-01

    In order to enhance the tracking velocity and accuracy of harmonic detection by ip-iq algorithm, a novel ip-iq control algorithm based on the Instantaneous reactive power theory is presented, the improved algorithm adds the lead correction link to adjust the zero point of the detection system, the Fuzzy Self-Tuning Adaptive PI control is introduced to dynamically adjust the DC-link Voltage, which meets the requirement of the harmonic compensation of the micro grid. Simulation and experimental results verify the proposed method is feasible and effective in micro grid.

  19. Integrated approach to economical, reliable, safe nuclear power production

    International Nuclear Information System (INIS)

    1982-06-01

    An Integrated Approach to Economical, Reliable, Safe Nuclear Power Production is the latest evolution of a concept which originated with the Defense-in-Depth philosophy of the nuclear industry. As Defense-in-Depth provided a framework for viewing physical barriers and equipment redundancy, the Integrated Approach gives a framework for viewing nuclear power production in terms of functions and institutions. In the Integrated Approach, four plant Goals are defined (Normal Operation, Core and Plant Protection, Containment Integrity and Emergency Preparedness) with the attendant Functional and Institutional Classifications that support them. The Integrated Approach provides a systematic perspective that combines the economic objective of reliable power production with the safety objective of consistent, controlled plant operation

  20. Integrated Control for Small Power Wind Generator

    Directory of Open Access Journals (Sweden)

    Hongliang Liu

    2018-05-01

    Full Text Available The control strategies of the small power wind generator are usually divided into the maximum power point tracking (MPPT case, which requires the wind generator produce power as much as possible, and the power limited control (PLC case that demands the wind generator produce a power level following the load requirement. Integration of these two operating cases responding to flexible and sophisticated power demands is the main topic of this article. A small power wind generator including the sluggish mechanical dynamic phenomenon, which uses the permanent magnet synchronous generator, is introduced to validate different control methods integrating MPPT and PLC cases and based on hysteresis control. It is a matter of an indirect power control method derived from three direct methods following perturb and observe principle as well as from a look-up table. To analyze and compare the proposed power control methods, which are implemented into an emulator of a small power wind generator, a power demand profile is used. This profile is randomly generated based on measured rapid wind velocity data. Analyzing experimental results, from the power viewpoint, all proposed methods reveal steady-state error with big amount of peak resulting from the nature of perturb and observe.

  1. IPS – A SYSTEM FOR REAL-TIME NAVIGATION AND 3D MODELING

    Directory of Open Access Journals (Sweden)

    D. Grießbach

    2012-07-01

    Full Text Available fdaReliable navigation and 3D modeling is a necessary requirement for any autonomous system in real world scenarios. German Aerospace Center (DLR developed a system providing precise information about local position and orientation of a mobile platform as well as three-dimensional information about its environment in real-time. This system, called Integral Positioning System (IPS can be applied for indoor environments and outdoor environments. To achieve high precision, reliability, integrity and availability a multi-sensor approach was chosen. The important role of sensor data synchronization, system calibration and spatial referencing is emphasized because the data from several sensors has to be fused using a Kalman filter. A hardware operating system (HW-OS is presented, that facilitates the low-level integration of different interfaces. The benefit of this approach is an increased precision of synchronization at the expense of additional engineering costs. It will be shown that the additional effort is leveraged by the new design concept since the HW-OS methodology allows a proven, flexible and fast design process, a high re-usability of common components and consequently a higher reliability within the low-level sensor fusion. Another main focus of the paper is on IPS software. The DLR developed, implemented and tested a flexible and extensible software concept for data grabbing, efficient data handling, data preprocessing (e.g. image rectification being essential for thematic data processing. Standard outputs of IPS are a trajectory of the moving platform and a high density 3D point cloud of the current environment. This information is provided in real-time. Based on these results, information processing on more abstract levels can be executed.

  2. Analysis of Handoff Mechanisms in Mobile IP

    Science.gov (United States)

    Jayaraj, Maria Nadine Simonel; Issac, Biju; Haldar, Manas Kumar

    2011-06-01

    One of the most important challenges in mobile Internet Protocol (IP) is to provide service for a mobile node to maintain its connectivity to network when it moves from one domain to another. IP is responsible for routing packets across network. The first major version of IP is the Internet Protocol version 4 (IPv4). It is one of the dominant protocols relevant to wireless network. Later a newer version of IP called the IPv6 was proposed. Mobile IPv6 is mainly introduced for the purpose of mobility. Mobility management enables network to locate roaming nodes in order to deliver packets and maintain connections with them when moving into new domains. Handoff occurs when a mobile node moves from one network to another. It is a key factor of mobility because a mobile node can trigger several handoffs during a session. This paper briefly explains on mobile IP and its handoff issues, along with the drawbacks of mobile IP.

  3. Direct reduction of N-acetoxy-PhIP by tea polyphenols: a possible mechanism for chemoprevention against PhIP-DNA adduct formation

    International Nuclear Information System (INIS)

    Lin Dongxin; Thompson, Patricia A.; Teitel, Candee; Chen Junshi; Kadlubar, Fred F.

    2003-01-01

    The chemopreventive effect of tea against 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adduct formation and its mechanism were studied. Rats were exposed to freshly prepared aqueous extracts of green tea (3% (w/v)) as the sole source of drinking water for 10 days prior to administration with a single dose of PhIP (10 mg/kg body weight) by oral gavage. PhIP-DNA adducts in the liver, colon, heart, and lung were measured using the 32 P-postlabelling technique. Rats pre-treated with tea and given PhIP 20 h before sacrifice had significantly reduced levels of PhIP-DNA adducts as compared with controls given PhIP alone. The possible mechanism of protective effect of tea on PhIP-DNA adduct formation was then examined in vitro. It was found that an aqueous extract of green and black tea, mixtures of green and black tea polyphenols, as well as purified polyphenols could strongly inhibit the DNA binding of N-acetoxy-PhIP, a putative ultimate carcinogen of PhIP formed in vivo via metabolic activation. Among these, epigallocatechin gallate was exceptionally potent. HPLC analyses of these incubation mixtures containing N-acetoxy-PhIP and the tea polyphenols each revealed the production of the parent amine, PhIP, indicating the involvement of a redox mechanism. In view of the presence of relatively high levels of tea polyphenols in rat and human plasma after ingestion of tea, this study suggests that direct reduction of the ultimate carcinogen N-acetoxy-PhIP by tea polyphenols is likely to be involved in the mechanism of chemoprotection of tea against this carcinogen

  4. Integration of power to gas/power to liquid in the ongoing transformation processes; Integration von Power to Gas/Power to Liquid in den laufenden Transformationsprozess

    Energy Technology Data Exchange (ETDEWEB)

    Purr, Katja; Osiek, Dirk; Lange, Martin; and others

    2016-03-15

    The objective of this position paper is to assess from the current level of knowledge of the Federal Environment Agency the role and perspective of power to gas / power to Liquid (PtG / PtL) in a fully renewable energy system and in particular to appoint the challenges of integration and further development of this technique in the current transformation process in the next few years. Here also the comparison to other Power to X-options and their greenhouse gas reduction effect is shown. The geographic focus of the considerations is on Germany, knowing that a full renewable energy supply in Germany must be especially for economic reasons embedded in a long term international energy policy. [German] Ziel dieses Positionspapiers ist es, aus dem derzeitigen Kenntnisstand des Umweltbundesamts die Rolle und Perspektive von Power to Gas/Power to Liquid (PtG/PtL) in einem vollstaendig regenerativen Energiesystem einzuschaetzen und insbesondere die Herausforderungen bei der Integration und Weiterentwicklung dieser Technik im laufenden Transformationsprozess in den naechsten Jahren zu benennen. Dabei wird auch der Vergleich zu anderen Power to X-Optionen und deren Treibhausgasminderungswirkung dargestellt. Der geografische Fokus der Betrachtungen liegt dabei auf Deutschland, wohlwissend, dass eine vollstaendige regenerative Energieversorgung Deutschlands insbesondere aus oekonomischen Gruenden langfristig in eine internationale Energiepolitik eingebettet sein muss.

  5. A study on opening displacement of lid and decrease in shielding thickness of a type IP-2 transport package in drop events

    International Nuclear Information System (INIS)

    Kim, Dong Hak; Seo, Ki Seog; Kim, Jae Yong; Lee, Ju Chan; Yoon, Jeong Hyoun; Lee, Kyung Ho; Kim, Sung Hwan; Lee, Heung Young

    2005-01-01

    Radioactive waste generated from nuclear power plants shall be transported in accordance with designated regulations, which is to protect radiation workers and the public against potential radiation exposure caused by the transportations. Each transport package of radioactive waste is to be designed to have enough safety to fulfill with the regulations and technical standards in domestic and foreign regulations. In accordance with IAEA safety standard series TS-R-1 which is widely accepted by most of its member states, industrial package can be divided into IP-1, IP-2 and IP-3 along with other Type A and Type B packages, a conventional clarification. IP-2 package shall be designed to meet the designated requirements in addition to those for type IP-1 package. IP-2 package is subject to the free drop and stacking tests under normal conditions of transport as regulated in the regulation. In this paper, opening displacement of lid and body and decrease in shielding thickness of an IP-2 package are analytically evaluated, which is proposed for on-site transportation in domestic nuclear power plants. The results of the analysis is compared with design requirements of the package that loss or dispersal of the radioactive contents should be prevented and total loss of shielding effect from free drop shall be less than 20%

  6. IP3 levels and their modulation FY fusicoccin measured by a novel [3H] IP3 binding assay

    International Nuclear Information System (INIS)

    Aducci, P.; Marra, M.

    1990-01-01

    A recently developed sensitive assay based on the binding reaction of IP3 to bovine adrenal preparations has been utilized for determining the level of endogenous inositol-1,4,5 trisphosphate (IP3) in maize roots and coleoptiles. The amount of IP3 found in these tissues ranges from 0.1 to 1.0 nmol g-1 fresh weight. Reproducible results were obtained with extracts of tissues from a same harvest, while they showed a 2-3 fold variation when different batches of plantlets were compared. The fungal phytotoxin fusicoccin (FC) known to affect several physiological processes in higher plants, increases the level of IP3 in coleoptiles. This observation suggests that IP3 might be involved in the transduction of the FC encoded signal from its receptors at the plasmalemma level to the cell machinery

  7. KEEFEKTIFAN MODEL CONNECTED DAN INTEGRATED DALAM PEMBELAJARAN IPS SMP DI KOTA YOGYAKARTA

    Directory of Open Access Journals (Sweden)

    Idrus idrus

    2011-01-01

    Full Text Available This research aimed to: (1 analyze the differences in social studies learning achievement between the students using connected and integrated models and those using conventional model; and (2 analyze the hierarchy of the effect of the learning models  among the connected, integrated, and conventional. This experimental research employed a matching post-test comparison group design. The population of this research was National Standardized Schools of Junior Secondary Schools in Yogyakarta. The technique used for sample drawing was multistage sampling. In this research, the independent variable was the learning model which consisted of three categories: integrated, connected, and conventional models. The dependent variable was the mean score of students’ learning achievement in social studies subject. Data collection was done by means of an achievement test. Instrument validation was done by discriminating power and difficulty index, while the reliability was calculated by KR-20. The pre-requisite  test included normality and homogeneity tests. The normality test used Kolmogorov-Smirnov and the homogeneity test used Levene Test. Data were analyzed in one way anova analysis and continued with Scheffe comparison test on the significance level of 0.05. The results of the experiment show that there are  significant difference among the students’ learning achievement who used integrated, connected, and conventional models. The continued test using Scheffe ensured that the integrated model was more effective than the connected and conventional models, while the connected model was more effective in improving the students’ learning achievement in social studies subject compared with the conventional model. Therefore, the hierarchy of the effect of the learning models is first the integrated model followed by connected and conventional models. Key words: Connected, Integrated Models, Social Studies Learning

  8. Smart power systems and renewable energy system integration

    CERN Document Server

    2016-01-01

    This monograph presents a wider spectrum of researches, developments, and case specific studies in the area of smart power systems and integration of renewable energy systems. The book will be for the benefit of a wider audience including researchers, postgraduate students, practicing engineers, academics, and regulatory policy makers. It covers a wide range of topics from fundamentals, and modelling and simulation aspects of traditional and smart power systems to grid integration of renewables; Micro Grids; challenges in planning and operation of a smart power system; risks, security, and stability in smart operation of a power system; and applied research in energy storage. .

  9. Host based internet protocol (IP) packet analysis to enhance network security

    International Nuclear Information System (INIS)

    Ahmad, T.; Ahmad, S.Z.; Yasin, M.M.

    2007-01-01

    Data communication in a computer network environment is facing serious security threats from numerous sources such as viruses, worms, Zombies etc. These threats can be broadly characterized as internal or external security threats. Internal threats are mainly attributed to sneaker-nets, utility modems and unauthorized users, which can be minimized by skillful network administration, password management and optimum usage policy definition. The external threats need more serious attention as these attacks are mostly coming from public networks such as Internet. Frequency and complexity of such attacks is much higher as compared to internal attacks. This paper presents a host based network layer screening of external and internal IP packets for logging, analyzing and real-time detection of possible IP spoofing and Denial of Service attacks. This work can also be used in tuning security rules definition for gateway firewalls. Software has been developed which intercepts IP traffic and analyses it with respect to integrity and origin of I P packet. The received IP packets are parsed and analyzed for possible signs of intrusion. The results show that by watching and categorizing composition of various transport protocol such as TCP, UDP, ICMP and others along with verifying the origin of received IP packet can help in devising real-time firewall rule and blocking possible external attack. This is highly desirable for fighting against zero day attacks and can result in a better Mean Time between Failures (MTBF) to increase the survivability of computer network. Used in a right context, packet screening and filtering can be a useful tool for provision of reliable and stable network services. (author)

  10. Analysis for Large Scale Integration of Electric Vehicles into Power Grids

    DEFF Research Database (Denmark)

    Hu, Weihao; Chen, Zhe; Wang, Xiaoru

    2011-01-01

    Electric Vehicles (EVs) provide a significant opportunity for reducing the consumption of fossil energies and the emission of carbon dioxide. With more and more electric vehicles integrated in the power systems, it becomes important to study the effects of EV integration on the power systems......, especially the low and middle voltage level networks. In the paper, the basic structure and characteristics of the electric vehicles are introduced. The possible impacts of large scale integration of electric vehicles on the power systems especially the advantage to the integration of the renewable energies...... are discussed. Finally, the research projects related to the large scale integration of electric vehicles into the power systems are introduced, it will provide reference for large scale integration of Electric Vehicles into power grids....

  11. Integration of torrefaction with steam power plant

    Energy Technology Data Exchange (ETDEWEB)

    Zakri, B.; Saari, J.; Sermyagina, E.; Vakkilainen, E.

    2013-09-01

    Torrefaction is one of the pretreatment technologies to enhance the fuel characteristics of biomass. The efficient and continuous operation of a torrefaction reactor, in the commercial scale, demands a secure biomass supply, in addition to adequate source of heat. Biorefinery plants or biomass-fuelled steam power plants have the potential to integrate with the torrefaction reactor to exchange heat and mass, using available infrastructure and energy sources. The technical feasibility of this integration is examined in this study. A new model for the torrefaction process is introduced and verified by the available experimental data. The torrefaction model is then integrated in different steam power plants to simulate possible mass and energy exchange between the reactor and the plants. The performance of the integrated plant is investigated for different configurations and the results are compared. (orig.)

  12. Enhanced service zone architecture for multiservices over IP

    Science.gov (United States)

    Michaely, Boaz; Mohan, Seshadri

    2001-07-01

    Recently, the field of IP Telephony has been experienced considerable evolution through the specification of new protocols and introduction of products implementing these protocols. We visualize IP Telephony evolving to soon offer multiservices encompassing not only voice, but also data, video and multimedia. While the progress has focused on refining protocols and architectures, very little attention has been given to business models for offering these services. This paper introduces the concept of a Service Zone, which from a service provider/network operator perspective fits within the operator's administrative domain, but is viewed as an independent zone with its own management and services, requiring minimal integration with the core network services. Besides its own management, the Enhanced Services Zone may also provide provisioning and maintenance features needed to provide the customer services and availability that subscribers expect from a telephony service providers. The platform must provide reliable service over time, be scalable to meet increased capacity demands, and be upgradeable to incorporate advanced services and features as they become available. Signaling flows are illustrated using SIP and H.323.

  13. HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data

    Directory of Open Access Journals (Sweden)

    Maher Christopher A

    2010-07-01

    Full Text Available Abstract Background Protein-DNA interaction constitutes a basic mechanism for the genetic regulation of target gene expression. Deciphering this mechanism has been a daunting task due to the difficulty in characterizing protein-bound DNA on a large scale. A powerful technique has recently emerged that couples chromatin immunoprecipitation (ChIP with next-generation sequencing, (ChIP-Seq. This technique provides a direct survey of the cistrom of transcription factors and other chromatin-associated proteins. In order to realize the full potential of this technique, increasingly sophisticated statistical algorithms have been developed to analyze the massive amount of data generated by this method. Results Here we introduce HPeak, a Hidden Markov model (HMM-based Peak-finding algorithm for analyzing ChIP-Seq data to identify protein-interacting genomic regions. In contrast to the majority of available ChIP-Seq analysis software packages, HPeak is a model-based approach allowing for rigorous statistical inference. This approach enables HPeak to accurately infer genomic regions enriched with sequence reads by assuming realistic probability distributions, in conjunction with a novel weighting scheme on the sequencing read coverage. Conclusions Using biologically relevant data collections, we found that HPeak showed a higher prevalence of the expected transcription factor binding motifs in ChIP-enriched sequences relative to the control sequences when compared to other currently available ChIP-Seq analysis approaches. Additionally, in comparison to the ChIP-chip assay, ChIP-Seq provides higher resolution along with improved sensitivity and specificity of binding site detection. Additional file and the HPeak program are freely available at http://www.sph.umich.edu/csg/qin/HPeak.

  14. Isolation, pointing, and suppression (IPS) system for high-performance spacecraft

    Science.gov (United States)

    Hindle, Tim; Davis, Torey; Fischer, Jim

    2007-04-01

    Passive mechanical isolation is often times the first step taken to remedy vibration issues on-board a spacecraft. In many cases, this is done with a hexapod of axial members or struts to obtain the desired passive isolation in all six degrees-of-freedom (DOF). In some instances, where the disturbance sources are excessive or the payload is particularly sensitive to vibration, additional steps are taken to improve the performance beyond that of passive isolation. Additional performance or functionality can be obtained with the addition of active control, using a hexapod of hybrid (passive/active) elements at the interface between the payload and the bus. This paper describes Honeywell's Isolation, Pointing, and Suppression (IPS) system. It is a hybrid isolation system designed to isolate a sensitive spacecraft payload with very low passive resonant break frequencies while affording agile independent payload pointing, on-board payload disturbance rejection, and active isolation augmentation. This system is an extension of the work done on Honeywell's previous Vibration Isolation, Steering, and Suppression (VISS) flight experiment. Besides being designed for a different size payload than VISS, the IPS strut includes a dual-stage voice coil design for improved dynamic range as well as improved low-noise drive electronics. In addition, the IPS struts include integral load cells, gap sensors, and payloadside accelerometers for control and telemetry purposes. The associated system-level control architecture to accomplish these tasks is also new for this program as compared to VISS. A summary of the IPS system, including analysis and hardware design, build, and single axis bipod testing will be reviewed.

  15. The future of integrated coal gasification combined cycle power plants

    International Nuclear Information System (INIS)

    Mueller, R.; Termuehlen, H.

    1991-01-01

    This paper examines the future of integrated coal gasification combined cycle (IGCC) power plants as affected by various technical, economical and environmental trends in power generation. The topics of the paper include a description of natural gas-fired combined cycle power plants, IGCC plants, coal gasifier concepts, integration of gasifiers into combined cycle power plants, efficiency, environmental impacts, co-products of IGCC power plants, economics of IGCC power plants, and a review of IGCC power plant projects

  16. How 60 Minutes ticked off Illinois Power

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    A November 60 Minutes broadcast on CBS television asserting that costs are out of control at the Illinois Power Co's(IP) Clinton nuclear power project because of management incompetence triggered a series of rebuttals and counter-rebuttals. A review of the events and correspondence during the planning stage and after the broadcast explores the question of construction cost overruns and the economic impact the broadcast had on IP's investors, employees, and customers. A parallel filming by IP was aired to show how the CBS edited the interview with IP officials. IP personnel feel betrayed by what they consider misconceptions and errors in the broadcast and are unhappy that an employee morale problem was worsened. Counter-arguments by both parties indicate a disagreement on both facts and interpretations

  17. Overview of Power Quality and Integrated Testing at JSC

    Science.gov (United States)

    Davies, Francis

    2018-01-01

    This presentation describes the basic philosophy behind integrated testing and partially integrated testing. It lists some well known errors in space systems that were or could have been caught during integrated testing. Two examples of integrated testing at the Johnson Space Center (JSC) are mentioned, and then an overview of two test facilities that do power testing (partially integrated testing) at JSC are presented, with information on the capabilities of each. Finally a list of three projects that has problems caught during power quality or Electromagnetic Interference (EMI) testing is presented.

  18. Clinical performance of IPS-Empress 2 ceramic crowns inserted by general dental practitioners.

    Science.gov (United States)

    Mansour, Yasar F; Al-Omiri, Mahmoud K; Khader, Yousef Saleh; Al-Wahadni, Ahed

    2008-05-01

    The aim of this study was to evaluate the clinical performance of IPS-Empress 2(R) all-ceramic crowns placed by general dental practitioners. Eighty-two IPS-Empress 2 crowns placed in 64 patients (27 females and 37 males) were evaluated. These crowns had been in place for 15.2 to 57.2 months (mean 25.3 months, SD=9.3). Survival analysis was conducted using the Kaplan-Meier method. Of the 82 crowns 93.9% were rated satisfactory. In terms of the integrity of the restorations, fracture was observed in three crowns and two showed a crack upon transillumination. Five crowns were rated unsatisfactory for color match; one for marginal adaptation; and none for discoloration, secondary caries, or sensitivity. IPS-Empress 2(R) is a suitable material to fabricate all-ceramic crowns; when these all-ceramic crowns were inserted by general dental practitioners, they functioned satisfactorily with low failure rates during an observation period ranging between 15.2 to 57.2 months.

  19. Intellectual Property and Strategic Agreements (IP/SA) | FNLCR

    Science.gov (United States)

    What does IP/SA handle? IP/SA handles all invention issues including patents and copyrights. All employee inventionreports are filed through the IP/SA office for all activities under the OTS contract.Additionally,&nbs

  20. Integrated low power ultrasound sensor interfaces

    OpenAIRE

    Gustafsson, Martin

    2005-01-01

    Imagine that the technical development can take the ultrasound measurement systems from the large piece of machinery today, to a coin size system tomorrow. The factor that has reduced the size of electronic systems over time is integration and integrated circuits. In this thesis circuit simulator models of complete ultrasound systems are used to design custom integrated circuits. These circuits are optimized for low power consumption and small size. The models that are used predict the acoust...

  1. MOBILTEL - Mobile Multimodal Telecommunications dialogue system based on VoIP telephony

    Directory of Open Access Journals (Sweden)

    Anton Čižmár

    2009-10-01

    Full Text Available In this paper the project MobilTel ispresented. The communication itself is becoming amultimodal interactive process. The MobilTel projectprovides research and development activities inmultimodal interfaces area. The result is a functionalarchitecture for mobile multimodal telecommunicationsystem running on handheld device. The MobilTelcommunicator is a multimodal Slovak speech andgraphical interface with integrated VoIP client. Theother possible modalities are pen – touch screeninteraction, keyboard, and display on which theinformation is more user friendly presented (icons,emoticons, etc., and provides hyperlink and scrollingmenu availability.We describe the method of interaction between mobileterminal (PDA and MobilTel multimodal PCcommunicator over a VoIP WLAN connection basedon SIP protocol. We also present the graphicalexamples of services that enable users to obtaininformation about weather or information about trainconnection between two train stations.

  2. Opportunities for IP  in Communications Beyond 3G

    DEFF Research Database (Denmark)

    Nielsen, Thomas Toftegaard; Jacobsen, Rune H.

    2005-01-01

    Future communication will be based on TCP/IP as common network and transport layers to provide global connectivity to users and applications. IP is used to provide ubiquitous access across different access networks and exploits the benefits of a common connectivity layer while reducing the cost...... of operation and maintenance of the network. This paper discusses the opportunities for IP in the evolution towards a future broadband, all-IP mobile communication network. In particular, we argue for three opportunities for the future: Interworking access technologies over IP, IP layer transparency...

  3. Model integration and the economics of nuclear power

    International Nuclear Information System (INIS)

    Lundgren, S.

    1985-01-01

    The author proposes and applies a specific approach to model integration, i.e. the merger of two or several independently developed models. The approach is intended for integrations of activity analysis sector models and applied general equilibrium models. Model integration makes it possible to extend the range of applicability of applied general equilibrium models by exploiting the information contained in sector models. It also makes it possible to evaluate the validity of the partial equilibrium analyses in which sector models often are employed. The proposed approach is used to integrate a sector model of electricity and heat production with a general equilibrium model of the Swedish economy. Both models have been constructed within the research programme. The author uses the integrated model to look at two issues concerning the role of nuclear power on the Swedish electricity market: What are the likely consequences of a nuclear power discontinuation and how does the nuclear power investment programme of the 1970's and the early 1980's compare with a socially efficient one. (Author)

  4. Thermodynamic and economic analysis on geothermal integrated combined-cycle power plants

    International Nuclear Information System (INIS)

    Bettocchi, R.; Cantore, G.; Negri di Montenegro, G.; Gadda, E.

    1992-01-01

    This paper considers geothermal integrated power plants obtained matching a geothermal plant with, a two pressure level combined plant. The purpose of the paper is the evaluation of thermodynamic and economic aspects on geothermal integrated combined-cycle power plant and a comparison with conventional solutions. The results show that the integrated combined plant power is greater than the sum of combined cycle and geothermal plant powers considered separately and that the integrated plant can offer economic benefits reaching the 16% of the total capital required

  5. Mobile IP

    NARCIS (Netherlands)

    Heijenk, Geert; Sallent, S.; Pras, Aiko

    1999-01-01

    The Internet is growing exponentially, both in the amount of traffic carried, and in the amount of hosts connected. IP technology is becoming more and more important, in company networks (Intranets), and also in the core networks for the next generation mobile networks. Further, wireless access to

  6. PowerCube: Integrated Power, Propulsion, and Pointing for CubeSats, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The PowerCube is a 1U CubeSat module that provides integrated propulsion, power, and precision pointing to enable the low-cost CubeSat platform to be used to conduct...

  7. Wind power integration : From individual wind turbine to wind park as a power plant

    NARCIS (Netherlands)

    Zhou, Y.

    2009-01-01

    As power capacities of single wind turbine, single wind park and total wind power installation are continuously increasing, the wind power begins to challenge the safety operation of the power system. This thesis focuses on the grid integration aspects such as the dynamic behaviours of wind power

  8. Continuously Connected With Mobile IP

    Science.gov (United States)

    2002-01-01

    Cisco Systems developed Cisco Mobile Networks, making IP devices mobile. With this innovation, a Cisco router and its connected IP devices can roam across network boundaries and connection types. Because a mobile user is able to keep the same IP address while roaming, a live IP connection can be maintained without interruption. Glenn Research Center jointly tested the technology with Cisco, and is working to use it on low-earth-orbiting research craft. With Cisco's Mobile Networks functionality now available in Cisco IOS Software release 12.2(4)T, the commercial advantages and benefits are numerous. The technology can be applied to public safety, military/homeland security, emergency management services, railroad and shipping systems, and the automotive industry. It will allow ambulances, police, firemen, and the U.S. Coast Guard to stay connected to their networks while on the move. In the wireless battlefield, the technology will provide rapid infrastructure deployment for U.S. national defense. Airline, train, and cruise passengers utilizing Cisco Mobile Networks can fly all around the world with a continuous Internet connection. Cisco IOS(R) Software is a registered trademark of Cisco Systems.

  9. 76 FR 50726 - Integrated System Power Rates: Correction

    Science.gov (United States)

    2011-08-16

    ... DEPARTMENT OF ENERGY Southwestern Power Administration Integrated System Power Rates: Correction AGENCY: Southwestern Power Administration, DOE. ACTION: Notice of public review and comment; Correction... date listed for the combined Public Information and Comment Forum (Forum) was erroneously listed in the...

  10. 75 FR 13235 - IP-Enabled Services

    Science.gov (United States)

    2010-03-19

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 63 [WC Docket No. 04-36; FCC 09-40] IP-Enabled Services AGENCY: Federal Communications Commission ACTION: Final rule; announcement of effective date... Internet Protocol (VoIP) service the discontinuance obligations that apply to domestic non-dominant...

  11. A 10-bit 200-kS/s SAR ADC IP core for a touch screen SoC

    International Nuclear Information System (INIS)

    Tong Xingyuan; Yang Yintang; Zhu Zhangming; Sheng Wenfang

    2010-01-01

    Based on a 5 MSBs (most-significant-bits)-plus-5 LSBs (least-significant-bits) C-R hybrid D/A conversion and low-offset pseudo-differential comparison approach, with capacitor array axially symmetric layout topology and resistor string low gradient mismatch placement method, an 8-channel 10-bit 200-kS/s SAR ADC (successive-approximation-register analog-to-digital converter) IP core for a touch screen SoC (system-on-chip) is implemented in a 0.18 μm 1P5M CMOS logic process. Design considerations for the touch screen SAR ADC are included. With a 1.8 V power supply, the DNL (differential non-linearity) and INL (integral non-linearity) of this converter are measured to be about 0.32 LSB and 0.81 LSB respectively. With an input frequency of 91 kHz at 200-kS/s sampling rate, the spurious-free dynamic range and effective-number-of-bits are measured to be 63.2 dB and 9.15 bits respectively, and the power is about 136 μW. This converter occupies an area of about 0.08 mm 2 . The design results show that it is very suitable for touch screen SoC applications. (semiconductor integrated circuits)

  12. Agency IP Data

    Data.gov (United States)

    National Aeronautics and Space Administration — Public data set for NASA Agency Intellectual Property (IP). The distribution contains both Patent information as well as General Release of Open Source Software.

  13. Research of future network with multi-layer IP address

    Science.gov (United States)

    Li, Guoling; Long, Zhaohua; Wei, Ziqiang

    2018-04-01

    The shortage of IP addresses and the scalability of routing systems [1] are challenges for the Internet. The idea of dividing existing IP addresses between identities and locations is one of the important research directions. This paper proposed a new decimal network architecture based on IPv9 [11], and decimal network IP address from E.164 principle of traditional telecommunication network, the IP address level, which helps to achieve separation and identification and location of IP address, IP address form a multilayer network structure, routing scalability problem in remission at the same time, to solve the problem of IPv4 address depletion. On the basis of IPv9, a new decimal network architecture is proposed, and the IP address of the decimal network draws on the E.164 principle of the traditional telecommunication network, and the IP addresses are hierarchically divided, which helps to realize the identification and location separation of IP addresses, the formation of multi-layer IP address network structure, while easing the scalability of the routing system to find a way out of IPv4 address exhausted. In addition to modifying DNS [10] simply and adding the function of digital domain, a DDNS [12] is formed. At the same time, a gateway device is added, that is, IPV9 gateway. The original backbone network and user network are unchanged.

  14. IP Address Management Principles and Practice

    CERN Document Server

    Rooney, Timothy

    2010-01-01

    This book will be the first covering the subject of IP address management (IPAM). The practice of IPAM includes the application of network management disciplines to IP address space and associated network services, namely DHCP (Dynamic Host Configuration Protocol) and DNS (Domain Name System). The consequence of inaccurately configuring DHCP is that end users may not be able to obtain IP addresses to access the network. Without proper DNS configuration, usability of the network will greatly suffer as the name-to-address lookup process may fail. Imagine having to navigate to a website or send a

  15. [Modern research progress of traditional Chinese medicine based on integrative pharmacology].

    Science.gov (United States)

    Wang, Ping; Tang, Shi-Huan; Su, Jin; Zhang, Jia-Qi; Cui, Ru-Yi; Xu, Hai-Yu; Yang, Hong-Jun

    2018-04-01

    Integrative pharmacology (IP) is a discipline that studies the interaction, integration and principle of action of multiple components with the body, emphasizing the integrations of multi-level and multi-link, such as "whole and part", " in vivo and in vitro ", " in vivo process and activity evaluation". After four years of development and practice, the theory and method of IP has received extensive attention and application.In order to better promote the development of IP, this paper systematically reviews the concepts, research contents, research methods and application fields about IP. Copyright© by the Chinese Pharmaceutical Association.

  16. A hidden Ising model for ChIP-chip data analysis

    KAUST Repository

    Mo, Q.

    2010-01-28

    Motivation: Chromatin immunoprecipitation (ChIP) coupled with tiling microarray (chip) experiments have been used in a wide range of biological studies such as identification of transcription factor binding sites and investigation of DNA methylation and histone modification. Hidden Markov models are widely used to model the spatial dependency of ChIP-chip data. However, parameter estimation for these models is typically either heuristic or suboptimal, leading to inconsistencies in their applications. To overcome this limitation and to develop an efficient software, we propose a hidden ferromagnetic Ising model for ChIP-chip data analysis. Results: We have developed a simple, but powerful Bayesian hierarchical model for ChIP-chip data via a hidden Ising model. Metropolis within Gibbs sampling algorithm is used to simulate from the posterior distribution of the model parameters. The proposed model naturally incorporates the spatial dependency of the data, and can be used to analyze data with various genomic resolutions and sample sizes. We illustrate the method using three publicly available datasets and various simulated datasets, and compare it with three closely related methods, namely TileMap HMM, tileHMM and BAC. We find that our method performs as well as TileMap HMM and BAC for the high-resolution data from Affymetrix platform, but significantly outperforms the other three methods for the low-resolution data from Agilent platform. Compared with the BAC method which also involves MCMC simulations, our method is computationally much more efficient. Availability: A software called iChip is freely available at http://www.bioconductor.org/. Contact: moq@mskcc.org. © The Author 2010. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org.

  17. BEC-BCS crossover in a (p+ip)-wave pairing Hamiltonian coupled to bosonic molecular pairs

    International Nuclear Information System (INIS)

    Dunning, Clare; Isaac, Phillip S.; Links, Jon; Zhao, Shao-You

    2011-01-01

    We analyse a (p+ip)-wave pairing BCS Hamiltonian, coupled to a single bosonic degree of freedom representing a molecular condensate, and investigate the nature of the BEC-BCS crossover for this system. For a suitable restriction on the coupling parameters, we show that the model is integrable and we derive the exact solution by the algebraic Bethe ansatz. In this manner we also obtain explicit formulae for correlation functions and compute these for several cases. We find that the crossover between the BEC state and the strong pairing p+ip phase is smooth for this model, with no intermediate quantum phase transition.

  18. Operational Space Weather Products at IPS

    Science.gov (United States)

    Neudegg, D.; Steward, G.; Marshall, R.; Terkildsen, M.; Kennewell, J.; Patterson, G.; Panwar, R.

    2008-12-01

    IPS Radio and Space Services operates an extensive network (IPSNET) of monitoring stations and observatories within the Australasian and Antarctic regions to gather information on the space environment. This includes ionosondes, magnetometers, GPS-ISM, oblique HF sounding, riometers, and solar radio and optical telescopes. IPS exchanges this information with similar organisations world-wide. The Regional Warning Centre (RWC) is the Australian Space Forecast Centre (ASFC) and it utilizes this data to provide products and services to support customer operations. A wide range of customers use IPS services including; defence force and emergency services using HF radio communications and surveillance systems, organisations involved in geophysical exploration and pipeline cathodic protection, GPS users in aviation. Subscriptions to the alerts, warnings, forecasts and reports regarding the solar, geophysical and ionospheric conditions are distributed by email and Special Message Service (SMS). IPS also develops and markets widely used PC software prediction tools for HF radio skywave and surface wave (ASAPS/GWPS) and provides consultancy services for system planning.

  19. Dynamic Optimization for IPS2 Resource Allocation Based on Improved Fuzzy Multiple Linear Regression

    Directory of Open Access Journals (Sweden)

    Maokuan Zheng

    2017-01-01

    Full Text Available The study mainly focuses on resource allocation optimization for industrial product-service systems (IPS2. The development of IPS2 leads to sustainable economy by introducing cooperative mechanisms apart from commodity transaction. The randomness and fluctuation of service requests from customers lead to the volatility of IPS2 resource utilization ratio. Three basic rules for resource allocation optimization are put forward to improve system operation efficiency and cut unnecessary costs. An approach based on fuzzy multiple linear regression (FMLR is developed, which integrates the strength and concision of multiple linear regression in data fitting and factor analysis and the merit of fuzzy theory in dealing with uncertain or vague problems, which helps reduce those costs caused by unnecessary resource transfer. The iteration mechanism is introduced in the FMLR algorithm to improve forecasting accuracy. A case study of human resource allocation optimization in construction machinery industry is implemented to test and verify the proposed model.

  20. Parallel factor ChIP provides essential internal control for quantitative differential ChIP-seq.

    Science.gov (United States)

    Guertin, Michael J; Cullen, Amy E; Markowetz, Florian; Holding, Andrew N

    2018-04-17

    A key challenge in quantitative ChIP combined with high-throughput sequencing (ChIP-seq) is the normalization of data in the presence of genome-wide changes in occupancy. Analysis-based normalization methods were developed for transcriptomic data and these are dependent on the underlying assumption that total transcription does not change between conditions. For genome-wide changes in transcription factor (TF) binding, these assumptions do not hold true. The challenges in normalization are confounded by experimental variability during sample preparation, processing and recovery. We present a novel normalization strategy utilizing an internal standard of unchanged peaks for reference. Our method can be readily applied to monitor genome-wide changes by ChIP-seq that are otherwise lost or misrepresented through analytical normalization. We compare our approach to normalization by total read depth and two alternative methods that utilize external experimental controls to study TF binding. We successfully resolve the key challenges in quantitative ChIP-seq analysis and demonstrate its application by monitoring the loss of Estrogen Receptor-alpha (ER) binding upon fulvestrant treatment, ER binding in response to estrodiol, ER mediated change in H4K12 acetylation and profiling ER binding in patient-derived xenographs. This is supported by an adaptable pipeline to normalize and quantify differential TF binding genome-wide and generate metrics for differential binding at individual sites.

  1. Dynamic Mobile IP routers in ad hoc networks

    NARCIS (Netherlands)

    Kock, B.A.; Schmidt, J.R.

    2005-01-01

    This paper describes a concept combining mobile IP and ad hoc routing to create a robust mobile network. In this network all nodes are mobile and globally and locally reachable under the same IP address. Essential for implementing this network are the dynamic mobile IP routers. They act as gateways

  2. VoIP over WLAN

    OpenAIRE

    Nikkari, Joni

    2007-01-01

    Tässä opinnäytetyössä tutkitaan VoIP over WLAN -tekniikan mahdollisuuksia nykyaikaisessa käyttöympäristössä, sekä yritysmaailman että kotikäyttäjän näkökulmasta. Toimiakseen VoWLAN tarvitsee kaksi eri tekniikkaa: langattoman lähiverkon sekä WLAN-puhelimen, joka perustuu VoIP-tekniikkaan.; WLAN:ssa tietoliikenne kulkee normaalin kaapeloinnin sijasta radiotaajuuksia käyttämällä. Standardina toimii IEEE 802.11, joka määrittelee WLAN-verkkojen toiminnan. Standardia on kehitetty jatkuvasti, ja si...

  3. Protection against cancer by dietary IP6 and inositol.

    Science.gov (United States)

    Vucenik, Ivana; Shamsuddin, AbulKalam M

    2006-01-01

    Inositol hexaphosphate (IP(6)) is a naturally occurring polyphosphorylated carbohydrate, abundantly present in many plant sources and in certain high-fiber diets, such as cereals and legumes. In addition to being found in plants, IP(6) is contained in almost all mammalian cells, although in much smaller amounts, where it is important in regulating vital cellular functions such as signal transduction, cell proliferation, and differentiation. For a long time IP(6) has been recognized as a natural antioxidant. Recently IP(6) has received much attention for its role in cancer prevention and control of experimental tumor growth, progression, and metastasis. In addition, IP(6) possesses other significant benefits for human health, such as the ability to enhance immune system, prevent pathological calcification and kidney stone formation, lower elevated serum cholesterol, and reduce pathological platelet activity. In this review we show the efficacy and discuss some of the molecular mechanisms that govern the action of this dietary agent. Exogenously administered IP(6) is rapidly taken up into cells and dephosphorylated to lower inositol phosphates, which further affect signal transduction pathways resulting in cell cycle arrest. A striking anticancer action of IP(6) was demonstrated in different experimental models. In addition to reducing cell proliferation, IP(6) also induces differentiation of malignant cells. Enhanced immunity and antioxidant properties also contribute to tumor cell destruction. Preliminary studies in humans show that IP(6) and inositol, the precursor molecule of IP(6), appear to enhance the anticancer effect of conventional chemotherapy, control cancer metastases, and improve quality of life. Because it is abundantly present in regular diet, efficiently absorbed from the gastrointestinal tract, and safe, IP(6) + inositol holds great promise in our strategies for cancer prevention and therapy. There is clearly enough evidence to justify the

  4. Large-scale integration of wind power into power systems as well as on transmission networks for offshore wind power plants. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Betancourt, Uta; Ackermann, Thomas (eds.)

    2013-11-01

    This proceedings contains contributions to the followings main topics: Grid integration experiences; Flexibility and economics of integration; Voltage control issues; Offshore wind power plants; Forecasting; Grid code issues; HVDC connection issues; Frequency control issues; National grid's perspective; Power system balancing; Power system issues; New grid and generators issues; Flexibility with storage and demand side management; AC connected offshore wind power plants; Economic and market issues; Modelling issues; Offshore grid issues.

  5. Ifabiyi, IP

    African Journals Online (AJOL)

    Ifabiyi, IP. Vol 11, No 1 (2013) - Articles Analysis of the Impacts of Rainfall Variability on Public Water Supply in Ilorin, Nigeria Abstract. ISSN: 2006-7003. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of ...

  6. IndigoVision IP video keeps watch over remote gas facilities in Amazon rainforest

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2010-07-15

    In Brazil, IndigoVision's complete IP video security technology is being used to remotely monitor automated gas facilities in the Amazon rainforest. Twelve compounds containing millions of dollars of process automation, telemetry, and telecom equipment are spread across many thousands of miles of forest and centrally monitored in Rio de Janeiro using Control Center, the company's Security Management software. The security surveillance project uses a hybrid IP network comprising satellite, fibre optic, and wireless links. In addition to advanced compression technology and bandwidth tuning tools, the IP video system uses Activity Controlled Framerate (ACF), which controls the frame rate of the camera video stream based on the amount of motion in a scene. In the absence of activity, the video is streamed at a minimum framerate, but the moment activity is detected the framerate jumps to the configured maximum. This significantly reduces the amount of bandwidth needed. At each remote facility, fixed analog cameras are connected to transmitter nodules that convert the feed to high-quality digital video for transmission over the IP network. The system also integrates alarms with video surveillance. PIR intruder detectors are connected to the system via digital inputs on the transmitters. Advanced alarm-handling features in the Control Center software process the PIR detector alarms and alert operators to potential intrusions. This improves operator efficiency and incident response. 1 fig.

  7. An Efficient and Secure m-IPS Scheme of Mobile Devices for Human-Centric Computing

    Directory of Open Access Journals (Sweden)

    Young-Sik Jeong

    2014-01-01

    Full Text Available Recent rapid developments in wireless and mobile IT technologies have led to their application in many real-life areas, such as disasters, home networks, mobile social networks, medical services, industry, schools, and the military. Business/work environments have become wire/wireless, integrated with wireless networks. Although the increase in the use of mobile devices that can use wireless networks increases work efficiency and provides greater convenience, wireless access to networks represents a security threat. Currently, wireless intrusion prevention systems (IPSs are used to prevent wireless security threats. However, these are not an ideal security measure for businesses that utilize mobile devices because they do not take account of temporal-spatial and role information factors. Therefore, in this paper, an efficient and secure mobile-IPS (m-IPS is proposed for businesses utilizing mobile devices in mobile environments for human-centric computing. The m-IPS system incorporates temporal-spatial awareness in human-centric computing with various mobile devices and checks users’ temporal spatial information, profiles, and role information to provide precise access control. And it also can extend application of m-IPS to the Internet of things (IoT, which is one of the important advanced technologies for supporting human-centric computing environment completely, for real ubiquitous field with mobile devices.

  8. Generic 12-Bus Test System for Wind Power Integration Studies

    DEFF Research Database (Denmark)

    Adamczyk, Andrzej Grzegorz; Altin, Müfit; Göksu, Ömer

    2012-01-01

    , inertial response, frequency control, damping of electromechanical oscillations, balanced and unbalanced fault management, etc. Hence, the power system components: conventional power plants with controls, transmission lines, transformers and loads should be represented accurately to achieve realistic power......High wind power penetration levels into power systems requires an appropriate power system model when assessing impact on the overall system stability. The model should capture the wide range of dynamics related to the wind integration studies, such as voltage control, synchronizing power control...... system characteristics. Additionally, the power system model should be simple and computationally manageable in order to simulate multiple scenarios with different control parameters in a reasonable time. In this paper, a generic power system model is presented in order to comprehend the wind integration...

  9. Split degenerate states and stable p+ip phases from holography

    Energy Technology Data Exchange (ETDEWEB)

    Nie, Zhang-Yu; Zeng, Hui [Kunming University of Science and Technology, Kunming (China); Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing (China); Pan, Qiyuan [Hunan Normal Univ., Key Lab. of Low Dimensional Quantum Structures and Quantum Control of Ministry of Education, and Synergetic Innovation Center for Quantum Effects and Applications, Dept. of Physics, Changsha (China); Zeng, Hua-Bi [Yangzhou University, College of Physics Science and Technology, Yangzhou, Jiangsu (China); National Central University, Department of Physics, Chungli (China)

    2017-02-15

    In this paper, we investigate the p+ip superfluid phases in the complex vector field holographic p-wave model. We find that in the probe limit, the p+ip phase and the p-wave phase are equally stable, hence the p and ip orders can be mixed with an arbitrary ratio to form more general p+λip phases, which are also equally stable with the p-wave and p+ip phases. As a result, the system possesses a degenerate thermal state in the superfluid region. We further study the case on considering the back-reaction on the metric, and we find that the degenerate ground states will be separated into p-wave and p+ip phases, and the p-wave phase is more stable. Finally, due to the different critical temperature of the zeroth order phase transitions from p-wave and p+ip phases to the normal phase, there is a temperature region where the p+ip phase exists but the p-wave phase does not. In this region we find the stable holographic p+ip phase for the first time. (orig.)

  10. Electric vehicles and large-scale integration of wind power

    DEFF Research Database (Denmark)

    Liu, Wen; Hu, Weihao; Lund, Henrik

    2013-01-01

    with this imbalance and to reduce its high dependence on oil production. For this reason, it is interesting to analyse the extent to which transport electrification can further the renewable energy integration. This paper quantifies this issue in Inner Mongolia, where the share of wind power in the electricity supply...... was 6.5% in 2009 and which has the plan to develop large-scale wind power. The results show that electric vehicles (EVs) have the ability to balance the electricity demand and supply and to further the wind power integration. In the best case, the energy system with EV can increase wind power...... integration by 8%. The application of EVs benefits from saving both energy system cost and fuel cost. However, the negative consequences of decreasing energy system efficiency and increasing the CO2 emission should be noted when applying the hydrogen fuel cell vehicle (HFCV). The results also indicate...

  11. Bayesian Modeling of ChIP-chip Data Through a High-Order Ising Model

    KAUST Repository

    Mo, Qianxing

    2010-01-29

    ChIP-chip experiments are procedures that combine chromatin immunoprecipitation (ChIP) and DNA microarray (chip) technology to study a variety of biological problems, including protein-DNA interaction, histone modification, and DNA methylation. The most important feature of ChIP-chip data is that the intensity measurements of probes are spatially correlated because the DNA fragments are hybridized to neighboring probes in the experiments. We propose a simple, but powerful Bayesian hierarchical approach to ChIP-chip data through an Ising model with high-order interactions. The proposed method naturally takes into account the intrinsic spatial structure of the data and can be used to analyze data from multiple platforms with different genomic resolutions. The model parameters are estimated using the Gibbs sampler. The proposed method is illustrated using two publicly available data sets from Affymetrix and Agilent platforms, and compared with three alternative Bayesian methods, namely, Bayesian hierarchical model, hierarchical gamma mixture model, and Tilemap hidden Markov model. The numerical results indicate that the proposed method performs as well as the other three methods for the data from Affymetrix tiling arrays, but significantly outperforms the other three methods for the data from Agilent promoter arrays. In addition, we find that the proposed method has better operating characteristics in terms of sensitivities and false discovery rates under various scenarios. © 2010, The International Biometric Society.

  12. IP- -: A Reduced Internet Protocol for Optical Packet Networking

    Science.gov (United States)

    Ohta, Masataka; Fujikawa, Kenji

    IP- - is proposed as an Internet Protocol suitable for optical packet networking. As optical routers require much faster control than electric ones and lack of optical buffers other than those by fiber delay lines requires fixed time control, Internet Protocols must be at least as simple as IPv4 and much simpler than IPv6. IP- - also addresses issues of IP address space exhaustion and IP routing table explosion.

  13. Methods of formation of efficiency indexes of electric power sources integration in regional electric power systems

    International Nuclear Information System (INIS)

    Marder, L.I.; Myzin, A.I.

    1993-01-01

    A methodic approach to the grounding of the integration process efficiency within the Unified electric power system is given together with the selection of a rational areal structure and concentration of power-generating source capacities. Formation of an economic functional according to alternative scenavies including the cost components taking account of the regional interests is considered. A method for estimation and distribution of the effect from electric power production integration in the power systems under new economic conditions is proposed

  14. Hybrid integrated biological-solid-state system powered with adenosine triphosphate

    Science.gov (United States)

    Roseman, Jared M.; Lin, Jianxun; Ramakrishnan, Siddharth; Rosenstein, Jacob K.; Shepard, Kenneth L.

    2015-12-01

    There is enormous potential in combining the capabilities of the biological and the solid state to create hybrid engineered systems. While there have been recent efforts to harness power from naturally occurring potentials in living systems in plants and animals to power complementary metal-oxide-semiconductor integrated circuits, here we report the first successful effort to isolate the energetics of an electrogenic ion pump in an engineered in vitro environment to power such an artificial system. An integrated circuit is powered by adenosine triphosphate through the action of Na+/K+ adenosine triphosphatases in an integrated in vitro lipid bilayer membrane. The ion pumps (active in the membrane at numbers exceeding 2 × 106 mm-2) are able to sustain a short-circuit current of 32.6 pA mm-2 and an open-circuit voltage of 78 mV, providing for a maximum power transfer of 1.27 pW mm-2 from a single bilayer. Two series-stacked bilayers provide a voltage sufficient to operate an integrated circuit with a conversion efficiency of chemical to electrical energy of 14.9%.

  15. Covert Channels in SIP for VoIP Signalling

    Science.gov (United States)

    Mazurczyk, Wojciech; Szczypiorski, Krzysztof

    In this paper, we evaluate available steganographic techniques for SIP (Session Initiation Protocol) that can be used for creating covert channels during signaling phase of VoIP (Voice over IP) call. Apart from characterizing existing steganographic methods we provide new insights by introducing new techniques. We also estimate amount of data that can be transferred in signalling messages for typical IP telephony call.

  16. On-chip enzymatic microbiofuel cell-powered integrated circuits.

    Science.gov (United States)

    Mark, Andrew G; Suraniti, Emmanuel; Roche, Jérôme; Richter, Harald; Kuhn, Alexander; Mano, Nicolas; Fischer, Peer

    2017-05-16

    A variety of diagnostic and therapeutic medical technologies rely on long term implantation of an electronic device to monitor or regulate a patient's condition. One proposed approach to powering these devices is to use a biofuel cell to convert the chemical energy from blood nutrients into electrical current to supply the electronics. We present here an enzymatic microbiofuel cell whose electrodes are directly integrated into a digital electronic circuit. Glucose oxidizing and oxygen reducing enzymes are immobilized on microelectrodes of an application specific integrated circuit (ASIC) using redox hydrogels to produce an enzymatic biofuel cell, capable of harvesting electrical power from just a single droplet of 5 mM glucose solution. Optimisation of the fuel cell voltage and power to match the requirements of the electronics allow self-powered operation of the on-board digital circuitry. This study represents a step towards implantable self-powered electronic devices that gather their energy from physiological fluids.

  17. DiffServ resource management in IP-based radio access networks

    NARCIS (Netherlands)

    Heijenk, Geert; Karagiannis, Georgios; Rexhepi, Vlora; Westberg, Lars; prof.dr. Prasad, R.; prof.dr. Bach Andersen, J.

    2001-01-01

    The increasing popularity of the Internet, the flexibility of IP, and the wide deployment of IP technologies, as well as the growth of mobile communications have driven the development of IP-based solutions for wireless networking. The introduction of IP-based transport in Radio Access Networks

  18. Conference on renewable energies integration to power grids

    International Nuclear Information System (INIS)

    Laffaille, Didier; Bischoff, Torsten; Merkel, Marcus; Rohrig, Kurt; Glatigny, Alain; Quitmann, Eckard; Lehec, Guillaume; Teirlynck, Thierry; Stahl, Oliver

    2014-01-01

    The French-German office for Renewable energies (OFAEnR) organised a conference on renewable energies integration to power grids. In the framework of this French-German exchange of experience, more than 150 participants exchanged views on the perspectives and possible solutions of this integration in order to warrant the security of supplies and the grid stability in a context of increasing injection and decentralization of renewable power sources. This document brings together the available presentations (slides) made during this event: 1 - French distribution grids - Overview and perspectives (Didier Laffaille); 2 - Distribution Grids in Germany - Overview and Perspective (Torsten Bischoff); 3 - Integration of renewable energies into distribution grids - a case example from Germany (Marcus Merkel); 4 - Regeneratives Kombikraftwerk Deutschland: System Services with 100 % Renewable energies (Kurt Rohrig); 5 - Overview of the different grid instrumentation-control and automation tools (Alain Glatigny); 6 - Which Ancillary Services needs the Power System? The contribution from Wind Power Plants (Eckard Quitmann); 7 - The Flexibility Aggregator - the example of the GreenLys Project (Guillaume Lehec); 8 - Energy Pool - Providing flexibility to the electric system. Consumption cut-off solutions in France (Thierry Teirlynck); 9 - Demand Response experiences from Germany (Oliver Stahl)

  19. Integration of distributed generation in the power system

    CERN Document Server

    Bollen, Math H J

    2011-01-01

    "The integration of new sources of energy like wind power, solar-power, small-scale generation, or combined heat and power in the power grid is something that impacts a lot of stakeholders: network companies (both distribution and transmission), the owners and operators of the DG units, other end-users of the power grid (including normal consumers like you and me) and not in the least policy makers and regulators. There is a lot of misunderstanding about the impact of DG on the power grid, with one side (including mainly some but certainly not all, network companies) claiming that the lights will go out soon, whereas the other side (including some DG operators and large parks of the general public) claiming that there is nothing to worry about and that it's all a conspiracy of the large production companies that want to protect their own interests and keep the electricity price high. The authors are of the strong opinion that this is NOT the way one should approach such an important subject as the integration...

  20. A fast neutron detector with IP by track measurement

    International Nuclear Information System (INIS)

    Miao Zhengqiang; Yang Jun; Zhang Qiang; Zhao Xiangfeng; Wang Daohua

    2004-01-01

    Imaging Plate(IP) is very sensitive to electric particles, especially to heavy ions. As we know, the recoiling protons are produced while fast neutrons scattered in light material containing hydrogen. When the recoiling proton enters in the sensitive layer of IP, a track will be recorded by IP. In this paper, a fast neutron detector based on IP and (n, p) reaction is described in detail, the detector's efficiency is studied also. (authors)

  1. Security risks in IP telephony

    OpenAIRE

    Řezáč, Filip; Vozňák, Miroslav

    2010-01-01

    This paper deals with VoIP communication security and various techniques of VoIP attacks. We divided these threats in several categories according to their specific behaviour and their impact on the affected system. We also tried to find effective methods to prevent or mitigate these attacks. We focused our work on Spam over Internet Telephony (SPIT) as a real threat for the future. We have developed both a tool generating SPIT attacks and AntiSPIT tool defending communication systems against...

  2. Engineering of radioimmunoassay (RIA) IP10.1

    International Nuclear Information System (INIS)

    Hari Nurcahyadi

    2010-01-01

    Engineering of Radioimmunoassay (RIA) IP10.1 is an innovative by PRPN - BATAN in 2010. Innovations made to the device IP10.1 RIA is the sample changer system, sample changer system on the device RIA IP10.1 applied 2 linear axis system (X, Z) with AC servo motor. In the RIA IP10.1 also use 5 pieces of the detector, so the enumeration process 50 (Fifty) sample is expected to be faster. Like its predecessor, The whole enumeration, data collection procedures and mechanisms operating within this system is entirely controlled by a PC via an electronic module. Electronics module consists of a high voltage module, amplifier and signal processor module, the module enumerators, low-voltage module, the module driver motor controller and a USB interface. The data acquisition and communication system using a USB port with the computer. (author)

  3. Empirical Information Metrics for Prediction Power and Experiment Planning

    Directory of Open Access Journals (Sweden)

    Christopher Lee

    2011-01-01

    Full Text Available In principle, information theory could provide useful metrics for statistical inference. In practice this is impeded by divergent assumptions: Information theory assumes the joint distribution of variables of interest is known, whereas in statistical inference it is hidden and is the goal of inference. To integrate these approaches we note a common theme they share, namely the measurement of prediction power. We generalize this concept as an information metric, subject to several requirements: Calculation of the metric must be objective or model-free; unbiased; convergent; probabilistically bounded; and low in computational complexity. Unfortunately, widely used model selection metrics such as Maximum Likelihood, the Akaike Information Criterion and Bayesian Information Criterion do not necessarily meet all these requirements. We define four distinct empirical information metrics measured via sampling, with explicit Law of Large Numbers convergence guarantees, which meet these requirements: Ie, the empirical information, a measure of average prediction power; Ib, the overfitting bias information, which measures selection bias in the modeling procedure; Ip, the potential information, which measures the total remaining information in the observations not yet discovered by the model; and Im, the model information, which measures the model’s extrapolation prediction power. Finally, we show that Ip + Ie, Ip + Im, and Ie — Im are fixed constants for a given observed dataset (i.e. prediction target, independent of the model, and thus represent a fundamental subdivision of the total information contained in the observations. We discuss the application of these metrics to modeling and experiment planning.    

  4. The CMOS Integration of a Power Inverter

    OpenAIRE

    Mannarino, Eric Francis

    2016-01-01

    Due to their falling costs, the use of renewable energy systems is expanding around the world. These systems require the conversion of DC power into grid-synchronous AC power. Currently, the inverters that carry out this task are built using discrete transistors. TowerJazz Semiconductor Corp. has created a commercial CMOS process that allows for blocking voltages of up to 700 V, effectively removing the barrier to integrating power inverters onto a single chip. This thesis explores this proce...

  5. IP access networks with QoS support

    Science.gov (United States)

    Sargento, Susana; Valadas, Rui J. M. T.; Goncalves, Jorge; Sousa, Henrique

    2001-07-01

    The increasing demand of new services and applications is pushing for drastic changes on the design of access networks targeted mainly for residential and SOHO users. Future access networks will provide full service integration (including multimedia), resource sharing at the packet level and QoS support. It is expected that using IP as the base technology, the ideal plug-and-play scenario, where the management actions of the access network operator are kept to a minimum, will be achieved easily. This paper proposes an architecture for access networks based on layer 2 or layer 3 multiplexers that allows a number of simplifications in the network elements and protocols (e.g. in the routing and addressing functions). We discuss two possible steps in the evolution of access networks towards a more efficient support of IP based services. The first one still provides no QoS support and was designed with the goal of reusing as much as possible current technologies; it is based on tunneling to transport PPP sessions. The second one introduces QoS support through the use of emerging technologies and protocols. We illustrate the different phases of a multimedia Internet access session, when using SIP for session initiation, COPS for the management of QoS policies including the AAA functions and RSVP for resource reservation.

  6. Effect of CMOS Technology Scaling on Fully-Integrated Power Supply Efficiency

    OpenAIRE

    Pillonnet , Gaël; Jeanniot , Nicolas

    2016-01-01

    International audience; Integrating a power supply in the same die as the powered circuits is an appropriate solution for granular, fine and fast power management. To allow same-die co-integration, fully integrated DC-DC converters designed in the latest CMOS technologies have been greatly studied by academics and industrialists in the last decade. However, there is little study concerning the effects of the CMOS scaling on these particular circuits. To show the trends, this paper compares th...

  7. iTAR: a web server for identifying target genes of transcription factors using ChIP-seq or ChIP-chip data.

    Science.gov (United States)

    Yang, Chia-Chun; Andrews, Erik H; Chen, Min-Hsuan; Wang, Wan-Yu; Chen, Jeremy J W; Gerstein, Mark; Liu, Chun-Chi; Cheng, Chao

    2016-08-12

    Chromatin immunoprecipitation followed by massively parallel DNA sequencing (ChIP-seq) or microarray hybridization (ChIP-chip) has been widely used to determine the genomic occupation of transcription factors (TFs). We have previously developed a probabilistic method, called TIP (Target Identification from Profiles), to identify TF target genes using ChIP-seq/ChIP-chip data. To achieve high specificity, TIP applies a conservative method to estimate significance of target genes, with the trade-off being a relatively low sensitivity of target gene identification compared to other methods. Additionally, TIP's output does not render binding-peak locations or intensity, information highly useful for visualization and general experimental biological use, while the variability of ChIP-seq/ChIP-chip file formats has made input into TIP more difficult than desired. To improve upon these facets, here we present are fined TIP with key extensions. First, it implements a Gaussian mixture model for p-value estimation, increasing target gene identification sensitivity and more accurately capturing the shape of TF binding profile distributions. Second, it enables the incorporation of TF binding-peak data by identifying their locations in significant target gene promoter regions and quantifies their strengths. Finally, for full ease of implementation we have incorporated it into a web server ( http://syslab3.nchu.edu.tw/iTAR/ ) that enables flexibility of input file format, can be used across multiple species and genome assembly versions, and is freely available for public use. The web server additionally performs GO enrichment analysis for the identified target genes to reveal the potential function of the corresponding TF. The iTAR web server provides a user-friendly interface and supports target gene identification in seven species, ranging from yeast to human. To facilitate investigating the quality of ChIP-seq/ChIP-chip data, the web server generates the chart of the

  8. The ChIP-Seq tools and web server: a resource for analyzing ChIP-seq and other types of genomic data.

    Science.gov (United States)

    Ambrosini, Giovanna; Dreos, René; Kumar, Sunil; Bucher, Philipp

    2016-11-18

    ChIP-seq and related high-throughput chromatin profilig assays generate ever increasing volumes of highly valuable biological data. To make sense out of it, biologists need versatile, efficient and user-friendly tools for access, visualization and itegrative analysis of such data. Here we present the ChIP-Seq command line tools and web server, implementing basic algorithms for ChIP-seq data analysis starting with a read alignment file. The tools are optimized for memory-efficiency and speed thus allowing for processing of large data volumes on inexpensive hardware. The web interface provides access to a large database of public data. The ChIP-Seq tools have a modular and interoperable design in that the output from one application can serve as input to another one. Complex and innovative tasks can thus be achieved by running several tools in a cascade. The various ChIP-Seq command line tools and web services either complement or compare favorably to related bioinformatics resources in terms of computational efficiency, ease of access to public data and interoperability with other web-based tools. The ChIP-Seq server is accessible at http://ccg.vital-it.ch/chipseq/ .

  9. Integrated assessment of water-power grid systems under changing climate

    Science.gov (United States)

    Yan, E.; Zhou, Z.; Betrie, G.

    2017-12-01

    Energy and water systems are intrinsically interconnected. Due to an increase in climate variability and extreme weather events, interdependency between these two systems has been recently intensified resulting significant impacts on both systems and energy output. To address this challenge, an Integrated Water-Energy Systems Assessment Framework (IWESAF) is being developed to integrate multiple existing or developed models from various sectors. In this presentation, we are focusing on recent improvement in model development of thermoelectric power plant water use simulator, power grid operation and cost optimization model, and model integration that facilitate interaction among water and electricity generation under extreme climate events. A process based thermoelectric power water use simulator includes heat-balance, climate, and cooling system modules that account for power plant characteristics, fuel types, and cooling technology. The model is validated with more than 800 power plants of fossil-fired, nuclear and gas-turbine power plants with different cooling systems. The power grid operation and cost optimization model was implemented for a selected regional in the Midwest. The case study will be demonstrated to evaluate the sensitivity and resilience of thermoelectricity generation and power grid under various climate and hydrologic extremes and potential economic consequences.

  10. Wind power integration into the automatic generation control of power systems with large-scale wind power

    DEFF Research Database (Denmark)

    Basit, Abdul; Hansen, Anca Daniela; Altin, Müfit

    2014-01-01

    Transmission system operators have an increased interest in the active participation of wind power plants (WPP) in the power balance control of power systems with large wind power penetration. The emphasis in this study is on the integration of WPPs into the automatic generation control (AGC......) of the power system. The present paper proposes a coordinated control strategy for the AGC between combined heat and power plants (CHPs) and WPPs to enhance the security and the reliability of a power system operation in the case of a large wind power penetration. The proposed strategy, described...... and exemplified for the future Danish power system, takes the hour-ahead regulating power plan for generation and power exchange with neighbouring power systems into account. The performance of the proposed strategy for coordinated secondary control is assessed and discussed by means of simulations for different...

  11. Low Power Consumption Wireless Sensor Communication System Integrated with an Energy Harvesting Power Source

    Directory of Open Access Journals (Sweden)

    Vlad MARSIC

    2013-01-01

    Full Text Available This paper presents the testing results of a wireless sensor communication system with low power consumption integrated with an energy harvesting power source. The experiments focus on the system’s capability to perform continuous monitoring and to wirelessly transmit the data acquired from the sensors to a user base station, for realization of completely battery-free wireless sensor system. Energy harvesting technologies together with system design optimization for power consumption minimization ensure the system’s energy autonomous capability demonstrated in this paper by presenting the promising testing results achieved following its integration with structural health monitoring and body area network applications.

  12. An infrastructure with a unified control plane to integrate IP into optical metro networks to provide flexible and intelligent bandwidth on demand for cloud computing

    Science.gov (United States)

    Yang, Wei; Hall, Trevor

    2012-12-01

    The Internet is entering an era of cloud computing to provide more cost effective, eco-friendly and reliable services to consumer and business users and the nature of the Internet traffic will undertake a fundamental transformation. Consequently, the current Internet will no longer suffice for serving cloud traffic in metro areas. This work proposes an infrastructure with a unified control plane that integrates simple packet aggregation technology with optical express through the interoperation between IP routers and electrical traffic controllers in optical metro networks. The proposed infrastructure provides flexible, intelligent, and eco-friendly bandwidth on demand for cloud computing in metro areas.

  13. Presence in the IP Multimedia Subsystem

    Directory of Open Access Journals (Sweden)

    Ling Lin

    2007-01-01

    Full Text Available With an ever increasing penetration of Internet Protocol (IP technologies, the wireless industry is evolving the mobile core network towards all-IP network. The IP Multimedia Subsystem (IMS is a standardised Next Generation Network (NGN architectural framework defined by the 3rd Generation Partnership Project (3GPP to bridge the gap between circuit-switched and packet-switched networks and consolidate both sides into on single all-IP network for all services. In this paper, we provide an insight into the limitation of the presence service, one of the fundamental building blocks of the IMS. Our prototype-based study is unique of its kind and helps identifying the factors which limit the scalability of the current version of the presence service (3GPP TS 23.141 version 7.2.0 Release 7 [1], which will in turn dramatically limit the performance of advanced IMS services. We argue that the client-server paradigm behind the current IMS architecture does not suite the requirements of the IMS system, which defies the very purpose of its introduction. We finally elaborate on possible avenues for addressing this problem.

  14. On-line Monitoring of VoIP Quality Using IPFIX

    Directory of Open Access Journals (Sweden)

    Petr Matousek

    2014-01-01

    Full Text Available The main goal of VoIP services is to provide a reliable and high-quality voice transmission over packet networks. In order to prove the quality of VoIP transmission, several approaches were designed. In our approach, we are concerned about on-line monitoring of RTP and RTCP traffic. Based on these data, we are able to compute main VoIP quality metrics including jitter, delay, packet loss, and finally R-factor and MOS values. This technique of VoIP quality measuring can be directly incorporated into IPFIX monitoring framework where an IPFIX probe analyses RTP/RTCP packets, computes VoIP quality metrics, and adds these metrics into extended IPFIX flow records. Then, these extended data are stored in a central IPFIX monitoring system called collector where can be used for monitoring purposes. This paper presents a functional implementation of IPFIX plugin for VoIP quality measurement and compares the results with results obtained by other tools.

  15. Hybrid integrated biological-solid-state system powered with adenosine triphosphate.

    Science.gov (United States)

    Roseman, Jared M; Lin, Jianxun; Ramakrishnan, Siddharth; Rosenstein, Jacob K; Shepard, Kenneth L

    2015-12-07

    There is enormous potential in combining the capabilities of the biological and the solid state to create hybrid engineered systems. While there have been recent efforts to harness power from naturally occurring potentials in living systems in plants and animals to power complementary metal-oxide-semiconductor integrated circuits, here we report the first successful effort to isolate the energetics of an electrogenic ion pump in an engineered in vitro environment to power such an artificial system. An integrated circuit is powered by adenosine triphosphate through the action of Na(+)/K(+) adenosine triphosphatases in an integrated in vitro lipid bilayer membrane. The ion pumps (active in the membrane at numbers exceeding 2 × 10(6) mm(-2)) are able to sustain a short-circuit current of 32.6 pA mm(-2) and an open-circuit voltage of 78 mV, providing for a maximum power transfer of 1.27 pW mm(-2) from a single bilayer. Two series-stacked bilayers provide a voltage sufficient to operate an integrated circuit with a conversion efficiency of chemical to electrical energy of 14.9%.

  16. Feasible reactor power cutback logic development for an integral reactor

    International Nuclear Information System (INIS)

    Han, Soon-Kyoo; Lee, Chung-Chan; Choi, Suhn; Kang, Han-Ok

    2013-01-01

    Major features of integral reactors that have been developed around the world recently are simplified operating systems and passive safety systems. Even though highly simplified control system and very reliable components are utilized in the integral reactor, the possibility of major component malfunction cannot be ruled out. So, feasible reactor power cutback logic is required to cope with the malfunction of components without inducing reactor trip. Simplified reactor power cutback logic has been developed on the basis of the real component data and operational parameters of plant in this study. Due to the relatively high rod worth of the integral reactor the control rod assembly drop method which had been adapted for large nuclear power plants was not desirable for reactor power cutback of the integral reactor. Instead another method, the control rod assembly control logic of reactor regulating system controls the control rod assembly movements, was chosen as an alternative. Sensitivity analyses and feasibility evaluations were performed for the selected method by varying the control rod assembly driving speed. In the results, sensitivity study showed that the performance goal of reactor power cutback system could be achieved with the limited range of control rod assembly driving speed. (orig.)

  17. International energy technology collaboration: wind power integration into electricity systems

    International Nuclear Information System (INIS)

    Justus, D.

    2006-01-01

    A rapid growth of wind power since the 1990s has led to notable market shares in some electricity markets. This growth is concentrated in a few countries with effective Research, Development and Demonstration (RD and D) programmes and with policies that support its diffusion into the market place. The speed and depth of its penetration in these electricity markets have amplified the need to address grid integration concerns, so as not to impede the further penetration of wind power. Research on technologies, tools and practices for integrating large amounts of wind power into electricity supply systems is attempting to respond to this need. In recent years, existing international collaborative research efforts have expanded their focus to include grid integration of wind power and new consortia have been formed to pool knowledge and resources. Effective results benefit a few countries that already have a significant amount of wind in their electricity supply fuel mix, as well as to the potential large markets worldwide. This paper focuses on the challenge of bringing significant amounts of intermittent generating sources into grids dominated by large central generating units. It provides a brief overview of the growth of wind power, mainly since 1990, the technical and operational issues related to integration and selected collaborative programmes underway to address grid integration concerns. (author)

  18. Characterization of in vivo DNA-binding events of plant transcription factors by ChIP-seq

    NARCIS (Netherlands)

    Mourik, Van Hilda; Muiño, J.M.; Pajoro, Alice; Angenent, G.C.; Kaufmann, Kerstin

    2015-01-01

    Chromatin immunoprecipitation followed by next-generation sequencing (ChIP-seq) is a powerful technique for genome-wide identification of in vivo binding sites of DNA-binding proteins. The technique had been used to study many DNA-binding proteins in a broad variety of species. The basis of the

  19. Summarisation of construction and commissioning experience for nuclear power integrated test facility

    International Nuclear Information System (INIS)

    Xiao Zejun; Jia Dounan; Jiang Xulun; Chen Bingde

    2003-01-01

    Since the foundation of Nuclear Power Institute of China, it has successively designed various engineering experimental facilities, and constructed nuclear power experimental research base, and accumulated rich construction experiences of nuclear power integrated test facility. The author presents experience on design, construction and commissioning of nuclear power integrated test facility

  20. Security Considerations around End-to-End Security in the IP-based Internet of Things

    NARCIS (Netherlands)

    Brachmann, M.; Garcia-Mochon, O.; Keoh, S.L.; Kumar, S.S.

    2012-01-01

    The IP-based Internet of Things refers to the interconnection of smart objects in a Low-power and Lossy Network (LLN) with the Internetby means of protocols such as 6LoWPAN or CoAP. The provisioning of an end-to-end security connection is the key to ensure basic functionalities such as software

  1. Capturing value from Intellectual Property (IP) in a global environment

    DEFF Research Database (Denmark)

    Alcácer, Juan; Beukel, Karin; Cassiman, Bruno

    2017-01-01

    Globalization should provide firms with an opportunity to leverage their know-how and reputation across countries to create value. However, it remains challenging for them to actually capture that value using traditional Intellectual Property (IP) tools. In this paper, we document the strong growth...... in patents, trademarks, and industrial designs used by firms to protect their IP globally. We then show that IP protection remains fragmented; the quality of IP applications might be questionable; and developing a comprehensive IP footprint worldwide is very costly. Growing numbers of applications...

  2. Real-time capture and reconstruction system with multiple GPUs for a 3D live scene by a generation from 4K IP images to 8K holograms.

    Science.gov (United States)

    Ichihashi, Yasuyuki; Oi, Ryutaro; Senoh, Takanori; Yamamoto, Kenji; Kurita, Taiichiro

    2012-09-10

    We developed a real-time capture and reconstruction system for three-dimensional (3D) live scenes. In previous research, we used integral photography (IP) to capture 3D images and then generated holograms from the IP images to implement a real-time reconstruction system. In this paper, we use a 4K (3,840 × 2,160) camera to capture IP images and 8K (7,680 × 4,320) liquid crystal display (LCD) panels for the reconstruction of holograms. We investigate two methods for enlarging the 4K images that were captured by integral photography to 8K images. One of the methods increases the number of pixels of each elemental image. The other increases the number of elemental images. In addition, we developed a personal computer (PC) cluster system with graphics processing units (GPUs) for the enlargement of IP images and the generation of holograms from the IP images using fast Fourier transform (FFT). We used the Compute Unified Device Architecture (CUDA) as the development environment for the GPUs. The Fast Fourier transform is performed using the CUFFT (CUDA FFT) library. As a result, we developed an integrated system for performing all processing from the capture to the reconstruction of 3D images by using these components and successfully used this system to reconstruct a 3D live scene at 12 frames per second.

  3. Integrated project risk management of nuclear power projects

    International Nuclear Information System (INIS)

    Wang Xiaohui; Xu Yuanhui

    2001-01-01

    The concept and the features of risks in nuclear power projects are introduced, and in terms of nuclear power projects' own features, the Nuclear Power Project Integrated Risk Management Model is presented. The identification, estimation, evaluation, response plan development, control of risks and the theoretical basis of risk management are discussed. The model has feedback and control functions in order to control and manage the risks dynamically

  4. FAKTOR-FAKTOR YANG MEMPENGARUHI KESULITAN BELAJAR IPS TERPADU KELAS VII DI SMP NEGERI 1 PLANTUNGAN KABUPATEN KENDAL

    Directory of Open Access Journals (Sweden)

    Lina Maftukhah,

    2012-10-01

    Full Text Available Kesulitan belajar dipengaruhi oleh berbagai macam faktor, baik faktor intern maupun faktor ekstern. Berdasarkan hasil observasi dari data nilai UAS IPS Terpadu sebagian besar siswa kelas VII SMP Negeri 1 Plantungan mendapat nilai rendah dan menyebabkan tidak lulus KKM. Hal ini dapat dijadikan indikasi bahwa siswa mengalami kesulitan belajar IPS Terpadu. Permasalahan yang dikaji dalam penelitian ini adalah apa saja faktor-faktor yang mempengaruhi kesulitan belajar mata pelajaran IPS Terpadu Siswa Kelas VII dan faktor apakah yang lebih dominan mempengaruhi kesulitan belajar mata pelajaran IPS Terpadu Siswa Kelas VII SMP Negeri 1 Plantungan Kabupaten Kendal Tahun Ajaran 2011/2012. Penelitian ini bertujuan untuk mengetahui faktor-faktor apa saja yang mempengaruhi kesulitan belajar mata pelajaran IPS Terpadu dan faktor apakah yang lebih dominan mempengaruhi kesulitan belajar mata pelajaran IPS Terpadu. Penelitian ini dilakukan di SMP N egeri 1 Plantungan Kabupaten Kendal. Populasi penelitian ini adalah siswa kelas VII sebanyak 131 siswa. Pengambilan sampel dilakukan secara proposional claster random sampling dan didapat sampel sebanyak 100 siswa. Variabel dalam penelitian ini adalah faktor-faktor yang mempengaruhi kesulitan belajar IPS Terpadu kelas VII SMP Negeri 1 Plantungan Kabupaten Kendal. Metode pengumpulan data yang digunakan adalah metode kuesioner dan dokumentasi. Sedangkan untuk analisis data yang digunakan adalah analisis faktor dan deskriptif persentase. Berdasarkan analisis faktor terdapat 5 komponen yang akan membentuk 5 faktor baru. Adapun tingkat kesulitan belajar siswa dari 5 faktor baru berdasarkan uji Deskripsi Persentase sebagai berikut : (a kemampuan siswa 61,55%, (b kemampuan guru 66,75%, (c sarana penunjang 77,00%, (d dukungan sekolah 72,67%, (e dukungan keluarga 62,00%. Dari kelima faktor yang ada, faktor kemampuan siswa merupakan pengaruh yang paling dominan dengan koefisien varian sebesar 61,55% dengan kategori menghambat

  5. Enabling new e-health business models by converging IP-based and non-IP-based home networks

    OpenAIRE

    Hartog, F.T.H. den; Tijmes, M.R.; Cramer, E.R.; Noorbergen, A.

    2013-01-01

    Current efforts in extending the Internet are focused on achieving full support of services and user-centric content from sectors such as energy management, education, and e-health. Until recently, these sectors typically developed their own communication infrastructure and systems, leading to point solutions, often built on non-IP technologies. We describe a demonstrator that shows how a non-IP supporting Continua-certified health device, such as a weighing scale, can be unlocked for use by ...

  6. HPC Access Using KVM over IP

    Science.gov (United States)

    2007-06-08

    Lightwave VDE /200 KVM-over-Fiber (Keyboard, Video and Mouse) devices installed throughout the TARDEC campus. Implementation of this system required...development effort through the pursuit of an Army-funded Phase-II Small Business Innovative Research (SBIR) effort with IP Video Systems (formerly known as...visualization capabilities of a DoD High- Performance Computing facility, many advanced features are necessary. TARDEC-HPC’s SBIR with IP Video Systems

  7. Design and development of VHDL based IP core for coincidence analyzer for FPGA based TDCR system

    International Nuclear Information System (INIS)

    Agarwal, Shivam; Gupta, Ashutosh; Chaudhury, Probal; Sharma, M.K.; Kulkarni, M.S.

    2018-01-01

    The coincidence counting technique is used in activity measurement methods to determine the activity of radionuclide e.g. 4πβ-γ method and Triple to Double Coincidence Ratio (TDCR) method etc. The 4πβ-γ method requires two inputs Coincidence Analyzer (CA) whereas; TDCR method requires three inputs CA. A VHDL (Very High Speed Integrated Circuit Hardware Description Language) based IP (Intellectual Property) core for coincidence analyzer has been designed and implemented in FPGA (Field Programmable Gate Array) for TDCR system. The developed IP not only facilitates the coincidence counting of three channels simultaneously but also provides an extendable dead time feature

  8. IP3 stimulates CA++ efflux from fusogenic carrot protoplasts

    International Nuclear Information System (INIS)

    Rincon, M.; Boss, W.F.

    1986-01-01

    Polyphosphoinositide breakdown plays an important role in signal transduction in animal cells (Berridge and Irvine, 1984, Nature, 312:315). Upon stimulation, phospholipase C hydrolyzes phosphatidylinositol 4,5-bisphosphate to inositol 1,4,5-trisphosphate (IP 3 ) and diacylglycerol both of which act as cellular second messengers. IP 3 mobilizes Ca ++ from internal stores, hence the cytosolic free Ca ++ concentration increases and those physiological activities regulated by Ca ++ are stimulated. To test if plant cells also responded to IP 3 , Ca ++ efflux studies were done with fusogenic carrot protoplasts released in EGTA. The protoplasts were preloaded with 45 Ca ++ placed in a Ca ++ -free medium, and efflux determined as 45 Ca ++ loss from the protoplasts. IP 3 (10-20μM) caused enhanced 45 Ca ++ efflux and the response was sustained for at least 15 min. In plants, as in animals, the observed IP 3 -enhanced 45 Ca ++ efflux suggested that IP 3 released Ca ++ from internal stores, and the increased free cytosolic Ca ++ activated Ca ++ pumping mechanisms which restored the Ca ++ concentration in the cytosol to the normal level

  9. Development of an integrated database management system to evaluate integrity of flawed components of nuclear power plant

    International Nuclear Information System (INIS)

    Mun, H. L.; Choi, S. N.; Jang, K. S.; Hong, S. Y.; Choi, J. B.; Kim, Y. J.

    2001-01-01

    The object of this paper is to develop an NPP-IDBMS(Integrated DataBase Management System for Nuclear Power Plants) for evaluating the integrity of components of nuclear power plant using relational data model. This paper describes the relational data model, structure and development strategy for the proposed NPP-IDBMS. The NPP-IDBMS consists of database, database management system and interface part. The database part consists of plant, shape, operating condition, material properties and stress database, which are required for the integrity evaluation of each component in nuclear power plants. For the development of stress database, an extensive finite element analysis was performed for various components considering operational transients. The developed NPP-IDBMS will provide efficient and accurate way to evaluate the integrity of flawed components

  10. VoIP and PBX security and forensics a practical approach

    CERN Document Server

    Androulidakis, Iosif I

    2016-01-01

    This book begins with an introduction to PBXs (Private Branch Exchanges) and the scene, statistics and involved actors. It discusses confidentiality, integrity and availability threats in PBXs. The author examines the threats and the technical background as well as security and forensics involving PBXs. The purpose of this book is to raise user awareness in regards to security and privacy threats present in PBXs, helping both users and administrators safeguard their systems. The new edition includes a major update and extension to the VoIP sections in addition to updates to forensics.

  11. Power system integration of VSC-HVDC connected offshore wind power plants

    DEFF Research Database (Denmark)

    Zeni, Lorenzo; Kjær, Philip Carne

    This report presents an overview of challenges and solutions for the integration into the power system of offshore wind power plants (WPPs) connected to onshore grids through a voltage-source converter based high voltage direct current (VSC-HVDC) transmission system. Aspects that are touched upon...... of the network in the vicinity of the HVDC station and (iii) limiting characteristics of WPPs such as inherent control and communication delays, presence of mechanical resonances at the same frequency as POD and active power ramp-rate limitations. Clustering of wind power plants The proof of concept...... introduction to justify the study, describe the state-of-art and formulate the project’s objectives, the report is essentially divided into three parts, as follows. Control principles of offshore AC networks The control of offshore AC networks relies purely on power electronics, especially if Type 4 wind...

  12. Thermionic integrated circuit technology for high power space applications

    International Nuclear Information System (INIS)

    Yadavalli, S.R.

    1984-01-01

    Thermionic triode and integrated circuit technology is in its infancy and it is emerging. The Thermionic triode can operate at relatively high voltages (up to 2000V) and at least tens of amperes. These devices, including their use in integrated circuitry, operate at high temperatures (800 0 C) and are very tolerant to nuclear and other radiations. These properties can be very useful in large space power applications such as that represented by the SP-100 system which uses a nuclear reactor. This paper presents an assessment of the application of thermionic integrated circuitry with space nuclear power system technology. A comparison is made with conventional semiconductor circuitry considering a dissipative shunt regulator for SP-100 type nuclear power system rated at 100 kW. The particular advantages of thermionic circuitry are significant reductions in size and mass of heat dissipation and radiation shield subsystems

  13. Power and Responsibility in Therapy: Integrating Feminism and Multiculturalism

    Science.gov (United States)

    Williams, Elizabeth Nutt; Barber, Jill S.

    2004-01-01

    The integration of feminist and multicultural approaches to psychotherapy, called for many times, has not yet materialized. This article reviews possible reasons this integration has not taken place and offers an approach to integration based on the guiding principles of power and responsibility, which builds on previous theories and approaches.

  14. Economic Evaluation of Three Available Solutions for Promotion of Wind Power Integration

    Directory of Open Access Journals (Sweden)

    Hong-Kun Chen

    2017-01-01

    Full Text Available The limited operational flexibility of combined heat and power (CHP units is the main cause of wind power curtailment in the thermal-electrical power system of Northern China. Pumped hydrostorage (PHS, heat storage (HS, and electric boiler (EB are investigated as three alternative options for the promotion of wind power integration. On the basis of two linear models that determine the capacities of these three facilities required for integrating the curtailed wind power, economic evaluation in terms of investment costs and environmental benefits is presented. Analysis results show that HS requires the least investment and has a good performance of coal saving when accommodating the same amount of curtailed wind power. And EB has the greatest potential for wind power integration with the huge growth of installed capacity of wind power in the future.

  15. Economic Impact Assessment of Wind Power Integration: A Quasi-Public Goods Property Perspective

    Directory of Open Access Journals (Sweden)

    Huiru Zhao

    2015-08-01

    Full Text Available The integration of wind power into power grid will bring some impacts on the multiple subjects of electric power system. Economic impacts of wind power integration on multiple subjects of China’s electric power system were quantitatively assessed from Quasi-public goods property perspective in this paper. Firstly, the Quasi-public goods property of transmission services provided by power grid corporations was elaborated. Secondly, the multiple subjects of China’s electric power system, which include electricity generation enterprises (EGEs, power grid corporations (PGCs, electricity consumers (ECs, and environment, were detailed analyzed. Thirdly, based on the OPF-based nodal price model and transmission service cost allocation model, the economic impact assessment model of wind power integration was built from Quasi-public goods property perspective. Then, the IEEE-24 bus system employed in this paper was introduced according to current status of China’s electric power system, and the modeling of wind turbine was also introduced. Finally, the simulation analysis was performed, and the economic impacts of wind power integration on EGEs, PGCs, ECs and Environment were calculated. The results indicate, from Quasi-public goods property perspective, the wind power integration will bring positive impacts on EGEs, PGCs and Environment, while negative impacts on ECs. The findings can provide references for power system managers, energy planners, and policy makers.

  16. Power Loss Analysis for Wind Power Grid Integration Based on Weibull Distribution

    Directory of Open Access Journals (Sweden)

    Ahmed Al Ameri

    2017-04-01

    Full Text Available The growth of electrical demand increases the need of renewable energy sources, such as wind energy, to meet that need. Electrical power losses are an important factor when wind farm location and size are selected. The capitalized cost of constant power losses during the life of a wind farm will continue to high levels. During the operation period, a method to determine if the losses meet the requirements of the design is significantly needed. This article presents a Simulink simulation of wind farm integration into the grid; the aim is to achieve a better understanding of wind variation impact on grid losses. The real power losses are set as a function of the annual variation, considering a Weibull distribution. An analytical method has been used to select the size and placement of a wind farm, taking into account active power loss reduction. It proposes a fast linear model estimation to find the optimal capacity of a wind farm based on DC power flow and graph theory. The results show that the analytical approach is capable of predicting the optimal size and location of wind turbines. Furthermore, it revealed that the annual variation of wind speed could have a strong effect on real power loss calculations. In addition to helping to improve utility efficiency, the proposed method can develop specific designs to speeding up integration of wind farms into grids.

  17. Mobile IP: state of the art report

    NARCIS (Netherlands)

    Karagiannis, Georgios; Heijenk, Geert

    Due to roaming, a mobile device may change its network attachment each time it moves to a new link. This might cause a disruption for the Internet data packets that have to reach the mobile node. Mobile IP is a protocol, developed by the Mobile IP Internet Engineering Task Force (IETF) working

  18. Quantitative analysis of macro-ARG using IP system

    International Nuclear Information System (INIS)

    Nakajima, Eiichi; Kawai, Kenji; Furuta, Yoshitake

    1997-01-01

    Recent progress in imaging plate (IP) system allow us to analyze autoradiographic images quantitatively. In the 'whole-body autoradiography', a method clarify the distribution of radioisotope or labeled compounds in the tissues and organs in a freeze-dried whole-body section of small animals such as rats and mice, the sections are pressed against a IP for exposure and the IP is scanned by Bio-Imaging Analyzer (Fuji Photo Film Co., Ltd) and a digital autoradiographic image is given. Quantitative data concerning the activity in different tissues can be obtained using an isotope scale as a reference source. Fading effect, application of IP system for distribution of receptor binding ARG, analysis of radio-spots on TLC and radioactive concentration in liquid such as blood are also discussed. (author)

  19. Integration of Small Solar tower Systems into Distributed Power Islands

    Energy Technology Data Exchange (ETDEWEB)

    Romero, M.; Marcos, M. J.; Tellez, F. M.; Blanco, M.; Fernandez, V.; Baonza, F.; Berger, S. [Ciemat, Madrid (Spain)

    2000-07-01

    One of the short-term priorities for renewable energies in Europe is their integration for local power supply into communities and energy islands (blocks of buildings, new neighborhoods in residential areas, shopping centers, hospitals, recreational areas, eco-paks, small rural areas or isolated ones such as islands or mountain communities). Following this strategy, the integration of small tower fields into so-called MIUS (Modular Integrated Utility Systems) is proposed. This application strongly influences field concepts leadings to modular multi-tower systems able to more closely track demand, meet reliability requirements with fewer megawatts of installed power and spread construction costs over time after output has begum. In addition, integration into single-cycle high-efficiency gas turbines plus waste-heat applications clearly increments the solar share. The chief questions are whether solar towers can be redesigned for such distributed markets and the keys to their feasibility. This paper includes the design and performance analysis of a 1.36-MW plant and integration in the MIUS system, as well as the expected cost of electricity and a sensitivity analysis of the small tower plant's performance with design parameters like heliostat configuration and tower height. A practical application is analyzed for a shopping center with 85% power demand during day-time by using a hybrid solar tower and a gas turbine producing electricity and waste heat for hot water and heating and cooling of spaces. The operation mode proposed is covering night demand with power from the grid and solar-gas power island mode during 14 hours daytime with a maximum power production of 1.36 MW. (Author) 26 refs.

  20. Integration of Small Solar Tower Systems Into Distributed Power Islands

    International Nuclear Information System (INIS)

    Romero, M.; Marcos, M. J.; Tellez, F. M.; Blanco, M.; Fernandez, V.; Baonza, F.; Berger, S.

    1999-01-01

    One of the short-term priorities for renewable energies in Europe is their integration for local power supply into communities and energy islands (blocks of buildings, new neighborhoods in residential areas, shopping centers, hospitals, recreational areas, eco-parks, small rural areas or isolated ones such as islands or mountain communities). Following this strategy, the integration of small tower fields into so-called MIUS (Modular Integrated Utility Systems) is proposed. This application strongly influences field concepts leading to modular multi-tower systems able to more closely track demand, meet reliability requirements with fewer megawatts of installed power and spread construction costs over time after output has begun. In addition, integration into single-cycle high-efficiency gas turbines plus waste-heat applications clearly increments the solar share. The chief questions are whether solar towers can be redesigned for such distributed markets and the keys to their feasibility. This paper includes the design and performance analysis of a 1.36-MW plant and integration in the MIUS system, as well as the expected cost of electricity and a sensitivity analysis of the small tower plant's performance with design parameters like heliostats configuration and tower height. A practical application is analyzed for a shopping center with 85% power demand during day-time by using a hybrid solar tower and a gas turbine producing electricity and waste heat for hot water and heating and cooling of spaces. The operation mode proposed is covering night demand with power from the grid and solar-gas power island mode during 14 hours daytime with a maximum power production of 1.36 MW. (Author) 26 refs

  1. Liquid Oxygen/Liquid Methane Integrated Power and Propulsion

    Science.gov (United States)

    Banker, Brian; Ryan, Abigail

    2016-01-01

    The proposed paper will cover ongoing work at the National Aeronautics and Space Administration (NASA) Johnson Space Center (JSC) on integrated power and propulsion for advanced human exploration. Specifically, it will present findings of the integrated design, testing, and operational challenges of a liquid oxygen / liquid methane (LOx/LCH4) propulsion brassboard and Solid Oxide Fuel Cell (SOFC) system. Human-Mars architectures point to an oxygen-methane economy utilizing common commodities, scavenged from the planetary atmosphere and soil via In-Situ Resource Utilization (ISRU), and common commodities across sub-systems. Due to the enormous mass gear-ratio required for human exploration beyond low-earth orbit, (for every 1 kg of payload landed on Mars, 226 kg will be required on Earth) increasing commonality between spacecraft subsystems such as power and propulsion can result in tremendous launch mass and volume savings. Historically, propulsion and fuel cell power subsystems have had little interaction outside of the generation (fuel cell) and consumption (propulsion) of electrical power. This was largely due to a mismatch in preferred commodities (hypergolics for propulsion; oxygen & hydrogen for fuel cells). Although this stove-piped approach benefits from simplicity in the design process, it means each subsystem has its own tanks, pressurization system, fluid feed system, etc. increasing overall spacecraft mass and volume. A liquid oxygen / liquid methane commodities architecture across propulsion and power subsystems would enable the use of common tankage and associated pressurization and commodity delivery hardware for both. Furthermore, a spacecraft utilizing integrated power and propulsion could use propellant residuals - propellant which could not be expelled from the tank near depletion due to hydrodynamic considerations caused by large flow demands of a rocket engine - to generate power after all propulsive maneuvers are complete thus utilizing

  2. Systems and methods for an integrated electrical sub-system powered by wind energy

    Science.gov (United States)

    Liu, Yan [Ballston Lake, NY; Garces, Luis Jose [Niskayuna, NY

    2008-06-24

    Various embodiments relate to systems and methods related to an integrated electrically-powered sub-system and wind power system including a wind power source, an electrically-powered sub-system coupled to and at least partially powered by the wind power source, the electrically-powered sub-system being coupled to the wind power source through power converters, and a supervisory controller coupled to the wind power source and the electrically-powered sub-system to monitor and manage the integrated electrically-powered sub-system and wind power system.

  3. A hybrid optical switch architecture to integrate IP into optical networks to provide flexible and intelligent bandwidth on demand for cloud computing

    Science.gov (United States)

    Yang, Wei; Hall, Trevor J.

    2013-12-01

    The Internet is entering an era of cloud computing to provide more cost effective, eco-friendly and reliable services to consumer and business users. As a consequence, the nature of the Internet traffic has been fundamentally transformed from a pure packet-based pattern to today's predominantly flow-based pattern. Cloud computing has also brought about an unprecedented growth in the Internet traffic. In this paper, a hybrid optical switch architecture is presented to deal with the flow-based Internet traffic, aiming to offer flexible and intelligent bandwidth on demand to improve fiber capacity utilization. The hybrid optical switch is capable of integrating IP into optical networks for cloud-based traffic with predictable performance, for which the delay performance of the electronic module in the hybrid optical switch architecture is evaluated through simulation.

  4. Power System Integration of Flexible Demand in the Low Voltage Network

    DEFF Research Database (Denmark)

    Thavlov, Anders

    , it is natural to consider electricity consumption from households as an integrated part of a potential flexible demand side in the future power system. However, as an individual unit a single household is not able to generate a large impact in the power system. Therefore, a mechanism is needed which can...... is even greater as almost 50% of the electricity consumption in households is utilised for space heating and cooling and for heating of domestic hot water. Consequently, there exists a significant potential in the integration of power consumption for heating purposes in households for demand response...... of electricity on the Nordic energy exchange, Nord Pool, or alternatively the flexibility can be sold as an ancillary service to the transmission system operator. In this way, the electricity consumption in households are indirectly integrated into the power market, through the virtual power plant...

  5. Vehicular Integration of Wireless Power Transfer Systems and Hardware Interoperability Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    Onar, Omer C [ORNL; Campbell, Steven L [ORNL; Seiber, Larry Eugene [ORNL; White, Cliff P [ORNL; Chinthavali, Madhu Sudhan [ORNL

    2016-01-01

    Several wireless charging methods are under development or available as an aftermarket option in the light-duty automotive market. However, there are not a sufficient number of studies detailing the vehicle integration methods, particularly a complete vehicle integration with higher power levels. This paper presents the design, development, implementation, and vehicle integration of wireless power transfer (WPT)-based electric vehicle (EV) charging systems for various test vehicles. Before having the standards effective, it is expected that WPT technology first will be integrated as an aftermarket retrofitting approach. Inclusion of this technology on production vehicles is contingent upon the release of the international standards. The power stages of the system are introduced with the design specifications and control systems including the active front-end rectifier with power factor correction, high frequency power inverter, high frequency isolation transformer, coupling coils, vehicle side full-bridge rectifier and filter, and the vehicle battery. The operating principles of the control, and communications, systems are presented. Aftermarket conversion approaches including the WPT on-board charger (OBC) integration, WPT CHAdeMO integration, and WPT direct battery connection scenarios are described. The experiments are carried out using the integrated vehicles and the results obtained to demonstrate the system performance including the stage-by-stage efficiencies.

  6. Power reserve provision with wind farms. Grid integration of wind power

    Energy Technology Data Exchange (ETDEWEB)

    Gesino, Alejandro J.

    2011-07-01

    Wind power is, admittedly, different from other power technologies and integrating large amounts of it in the existing power systems is a challenge that requires innovative approaches to keep the sustainability of the power system operation. In the coming years its contribution to the system security will become mandatory as far as the trend goes towards more decentralized structures and an increase in complexity due to a higher number of market participants. This PhD addresses one of the fundamental ancillary services researching about a secure and flexible methodology for power reserve provision with wind farms. Based on the current needs and security standards of those highly developed European grid codes, a new model for power reserve provision with wind power is developed. This methodology, algorithms and variables are tested based on real scenarios from five German wind farm clusters. Finally, once the methodology for power reserve provision with wind power has been tested, real control capabilities from already installed wind farms in Germany and Portugal are analyzed. Their capabilities of following control commands as well as an error deviation analysis are also presented. (orig.)

  7. Large-scale Wind Power integration in a Hydro-Thermal Power Market

    OpenAIRE

    Trøtscher, Thomas

    2007-01-01

    This master thesis describes a quadratic programming model used to calculate the spot prices in an efficient multi-area power market. The model has been adapted to Northern Europe, with focus on Denmark West and the integration of large quantities of wind power. In the model, demand and supply of electricity are equated, at an hourly time resolution, to find the spot price in each area. Historical load values are used to represent demand which is assumed to be completely inelastic. Supply i...

  8. Internetworking with TCP/IP

    CERN Document Server

    Comer, Douglas E

    2014-01-01

    An internationally best-selling, conceptual introduction to the TCP/IP protocols and Internetworking, this book interweaves a clear discussion of fundamentals and scientific principles with details and examples drawn from the latest technologies. Leading author Douglas Comer covers layering and packet formats for all the Internet protocols, includingTCP, IPv4, IPv6, DHCP, and DNS. In addition, the text explains new trends in Internet systems, including packet classification, Software Defined Networking (SDN), and mesh protocols used in The Internet of Things. The text is appropriate for individuals interested in learning more about TCP/IP protocols, Internet architecture, and current networking technologies, as well as engineers who build network systems. It is suitable for junior to graduate-level courses in Computer Networks, Data Networks, Network Protocols, and Internetworking.

  9. An Attacker-Defender Model for IP-Based Networks

    National Research Council Canada - National Science Library

    Barkley, Timothy R

    2008-01-01

    .... Because IP flows are defined essentially in terms of origin-destination (O-D) pairs, we represent IP traffic engineering as a multi-commodity flow problem in which each O-D pair is treated as a separate commodity...

  10. Wind power potential and integration in Africa

    Directory of Open Access Journals (Sweden)

    Agbetuyi, A.F.

    2013-03-01

    Full Text Available Wind energy penetration into power networks is increasing very rapidly all over the world. The great concern about global warming and continued apprehensions about nuclear power around the world should drive most countries in Africa into strong demand for wind generation because of its advantages which include the absence of harmful emissions, very clean and almost infinite availability of wind that is converted into electricity. This paper shows the power available in the wind. It also gives an overview of the wind power potential and integration in some selected Africa countries like Egypt, Morocco, South Africa and Nigeria and the challenges of wind power integration in Africa’s continent are also discussed. The Northern part of Africa is known to be Africa’s Wind pioneers having installed and connected the Wind Energy Converters (WEC to the grid. About 97% of the continent’s total wind installations are located in Egypt, Morocco and Tunisia. Research work should commence on the identified sites with high wind speeds in those selected Africa countries, so that those potential sites can be connected to the grid. This is because the ability of a site to sufficiently accommodate wind generation not only depends on wind speeds but on its ability to interconnect to the existing grid. If these wind energy potentials are tapped and connected to the grid, the erratic and epileptic power supply facing most countries in Africa will be reduced; thereby reducing rural-urban migration and more jobs will be created.

  11. Control and management of distribution system with integrated DERs via IEC 61850 based communication

    Directory of Open Access Journals (Sweden)

    Ikbal Ali

    2017-06-01

    Full Text Available Distributed Energy Resources (DERs are being increasingly integrated in the distribution systems and resulting in complex power flow scenarios. In such cases, effective control, management and protection of distribution systems becomes highly challenging. Standardized and interoperable communication in distribution systems has the potential to deal with such challenges to achieve higher energy efficiency and reliability. Ed. 2 of IEC 61850 standards, for utility automation, standardizing the exchange of data among different substations, DERs, control centers, PMUs and PDCs. This paper demonstrates the modelling of information and services needed for control, management and protection of distribution systems with integrated DERs. This paper has used IP tunnels and/or mapping over IP layer for transferring IEC 61850 messages, such as sample values (SVs and GOOSE (Generic Object Oriented Substation Event, over distribution system Wide Area Network (WAN. Finally performance of the proposed communication configurations for different applications is analyzed by calculating End-to-End (ETE delay, throughput and jitter.

  12. Design And Implementation of Low Area/Power Elliptic Curve Digital Signature Hardware Core

    Directory of Open Access Journals (Sweden)

    Anissa Sghaier

    2017-06-01

    Full Text Available The Elliptic Curve Digital Signature Algorithm(ECDSA is the analog to the Digital Signature Algorithm(DSA. Based on the elliptic curve, which uses a small key compared to the others public-key algorithms, ECDSA is the most suitable scheme for environments where processor power and storage are limited. This paper focuses on the hardware implementation of the ECDSA over elliptic curveswith the 163-bit key length recommended by the NIST (National Institute of Standards and Technology. It offers two services: signature generation and signature verification. The proposed processor integrates an ECC IP, a Secure Hash Standard 2 IP (SHA-2 Ip and Random Number Generator IP (RNG IP. Thus, all IPs will be optimized, and different types of RNG will be implemented in order to choose the most appropriate one. A co-simulation was done to verify the ECDSA processor using MATLAB Software. All modules were implemented on a Xilinx Virtex 5 ML 50 FPGA platform; they require respectively 9670 slices, 2530 slices and 18,504 slices. FPGA implementations represent generally the first step for obtaining faster ASIC implementations. Further, the proposed design was also implemented on an ASIC CMOS 45-nm technology; it requires a 0.257 mm2 area cell achieving a maximum frequency of 532 MHz and consumes 63.444 (mW. Furthermore, in this paper, we analyze the security of our proposed ECDSA processor against the no correctness check for input points and restart attacks.

  13. The wavy Mutation Maps to the Inositol 1,4,5-Trisphosphate 3-Kinase 2 (IP3K2) Gene of Drosophila and Interacts with IP3R to Affect Wing Development.

    Science.gov (United States)

    Dean, Derek M; Maroja, Luana S; Cottrill, Sarah; Bomkamp, Brent E; Westervelt, Kathleen A; Deitcher, David L

    2015-11-27

    Inositol 1,4,5-trisphosphate (IP3) regulates a host of biological processes from egg activation to cell death. When IP3-specific receptors (IP3Rs) bind to IP3, they release calcium from the ER into the cytoplasm, triggering a variety of cell type- and developmental stage-specific responses. Alternatively, inositol polyphosphate kinases can phosphorylate IP3; this limits IP3R activation by reducing IP3 levels, and also generates new signaling molecules altogether. These divergent pathways draw from the same IP3 pool yet cause very different cellular responses. Therefore, controlling the relative rates of IP3R activation vs. phosphorylation of IP3 is essential for proper cell functioning. Establishing a model system that sensitively reports the net output of IP3 signaling is crucial for identifying the controlling genes. Here we report that mutant alleles of wavy (wy), a classic locus of the fruit fly Drosophila melanogaster, map to IP3 3-kinase 2 (IP3K2), a member of the inositol polyphosphate kinase gene family. Mutations in wy disrupt wing structure in a highly specific pattern. RNAi experiments using GAL4 and GAL80(ts) indicated that IP3K2 function is required in the wing discs of early pupae for normal wing development. Gradations in the severity of the wy phenotype provide high-resolution readouts of IP3K2 function and of overall IP3 signaling, giving this system strong potential as a model for further study of the IP3 signaling network. In proof of concept, a dominant modifier screen revealed that mutations in IP3R strongly suppress the wy phenotype, suggesting that the wy phenotype results from reduced IP4 levels, and/or excessive IP3R signaling. Copyright © 2016 Dean et al.

  14. The wavy Mutation Maps to the Inositol 1,4,5-Trisphosphate 3-Kinase 2 (IP3K2 Gene of Drosophila and Interacts with IP3R to Affect Wing Development

    Directory of Open Access Journals (Sweden)

    Derek M. Dean

    2016-02-01

    Full Text Available Inositol 1,4,5-trisphosphate (IP3 regulates a host of biological processes from egg activation to cell death. When IP3-specific receptors (IP3Rs bind to IP3, they release calcium from the ER into the cytoplasm, triggering a variety of cell type- and developmental stage-specific responses. Alternatively, inositol polyphosphate kinases can phosphorylate IP3; this limits IP3R activation by reducing IP3 levels, and also generates new signaling molecules altogether. These divergent pathways draw from the same IP3 pool yet cause very different cellular responses. Therefore, controlling the relative rates of IP3R activation vs. phosphorylation of IP3 is essential for proper cell functioning. Establishing a model system that sensitively reports the net output of IP3 signaling is crucial for identifying the controlling genes. Here we report that mutant alleles of wavy (wy, a classic locus of the fruit fly Drosophila melanogaster, map to IP3 3-kinase 2 (IP3K2, a member of the inositol polyphosphate kinase gene family. Mutations in wy disrupt wing structure in a highly specific pattern. RNAi experiments using GAL4 and GAL80ts indicated that IP3K2 function is required in the wing discs of early pupae for normal wing development. Gradations in the severity of the wy phenotype provide high-resolution readouts of IP3K2 function and of overall IP3 signaling, giving this system strong potential as a model for further study of the IP3 signaling network. In proof of concept, a dominant modifier screen revealed that mutations in IP3R strongly suppress the wy phenotype, suggesting that the wy phenotype results from reduced IP4 levels, and/or excessive IP3R signaling.

  15. An integrated GIS environment enhancing the operation and planning of power utilities

    International Nuclear Information System (INIS)

    Yared, George Antoine

    1996-05-01

    The evolution of electrical power systems was tightly geared by the development of two fields: power engineering, with the advanced technology of physical elements comprising all parts of a power system, and information processing tools to manage the performance of electric power utilities. Compared to power engineering that has gone through tremendous developments, information technology applications for electrical power systems are relatively young. The possible improvements of these applications are in their graphical, mapping an data analysis capabilities. State-of-the art information technology such as Geographic Information Systems provides these facilities. The objective of this thesis is to devise a technique that combines power system software tools with the Geographic Information Systems software to enhance the operation, control and planning of electrical transmission systems. The load flow, voltage control and fault analysis models for the transmission system will be re-engineered in a Geographic Information System environment.The research is generic, special attention is given to its application to the Lebanese electrical power system, which is recovering from an infrastructure devastating war. The research entails integrating power systems analysis and control package, or PSACP developed at the AUB within a Geographic Information Systems environment. This will enhance the power modeling capabilities by the use of powerful thematic mapping, geographic and data analysis and user interface techniques that come with Geographic Information Systems. An overview of the two technologies involved is presented, followed by a detailed description of the integration technique before describing the integrated system. Moving to a higher level, the features of the system are presented, followed by sample applications of the integrated system on the Lebanese electrical power system. The thesis contributes to the research arena by developing a software re

  16. PRI-CAT: a web-tool for the analysis, storage and visualization of plant ChIP-seq experiments.

    NARCIS (Netherlands)

    Muino, J.M.; Hoogstraat, M.; Ham, van R.C.H.J.; Dijk, van A.D.J.

    2011-01-01

    Although several tools for the analysis of ChIP-seq data have been published recently, there is a growing demand, in particular in the plant research community, for computational resources with which such data can be processed, analyzed, stored, visualized and integrated within a single,

  17. CPICOR{trademark}: Clean power from integrated coal-ore reduction

    Energy Technology Data Exchange (ETDEWEB)

    Wintrell, R.; Miller, R.N.; Harbison, E.J.; LeFevre, M.O.; England, K.S.

    1997-12-31

    The US steel industry, in order to maintain its basic iron production, is thus moving to lower coke requirements and to the cokeless or direct production of iron. The US Department of Energy (DOE), in its Clean Coal Technology programs, has encouraged the move to new coal-based technology. The steel industry, in its search for alternative direct iron processes, has been limited to a single process, COREX{reg_sign}. The COREX{reg_sign} process, though offering commercial and environmental acceptance, produces a copious volume of offgas which must be effectively utilized to ensure an economical process. This volume, which normally exceeds the internal needs of a single steel company, offers a highly acceptable fuel for power generation. The utility companies seeking to offset future natural gas cost increases are interested in this clean fuel. The COREX{reg_sign} smelting process, when integrated with a combined cycle power generation facility (CCPG) and a cryogenic air separation unit (ASU), is an outstanding example of a new generation of environmentally compatible and highly energy efficient Clean Coal Technologies. This combination of highly integrated electric power and hot metal coproduction, has been designated CPICOR{trademark}, Clean Power from Integrated Coal/Ore Reduction.

  18. Understanding Innovative Potential (IP) in an ICT Context

    DEFF Research Database (Denmark)

    Rai, Sudhanshu

    a dynamic perspective in its conception, operation and instantiation. I conclude this paper with insights on what I call the dynamic IP threshold arguing that being dynamic cannot be seen as a point in time but a threshold existing over time. I then discuss some implications. I suggest that firms need...... to consider IP as a long term investment not only in human capital but in the way the human capital is allowed to engage with new ideas. I suggest IP can be build using institutional logics that enable openness and collegiality....

  19. Optimal integration of linear Fresnel reflector with gas turbine cogeneration power plant

    International Nuclear Information System (INIS)

    Dabwan, Yousef N.; Mokheimer, Esmail M.A.

    2017-01-01

    Highlights: • A LFR integrated solar gas turbine cogeneration plant (ISGCPP) has been simulated. • The optimally integrated LFR with gas turbine cogeneration plant can achieve an annual solar share of 23%. • Optimal integration of LFR with gas turbine cogeneration system can reduce CO 2 emission by 18%. • Compared to a fully-solar-powered LFR plant, the optimal ISGCPP reduces the LEC by 83%. • ISGCPP reduces the LEC by 50% compared to plants integrated with carbon capture technology. - Abstract: Solar energy is an abundant resource in many countries in the Sunbelt, especially in the middle east, countries, where recent expansion in the utilization of natural gas for electricity generation has created a significant base for introducing integrated solar‐natural gas power plants (ISGPP) as an optimal solution for electricity generation in these countries. ISGPP reduces the need for thermal energy storage in traditional concentrated solar thermal plants and results in dispatchable power on demand at lower cost than stand-alone concentrated thermal power and much cheaper than photovoltaic plants. Moreover, integrating concentrated solar power (CSP) with conventional fossil fuel based thermal power plants is quite suitable for large-scale central electric power generation plants and it can be implemented in the design of new installed plants or during retrofitting of existing plants. The main objective of the present work is to investigate the possible modifications of an existing gas turbine cogeneration plant, which has a gas turbine of 150 MWe electricity generation capacity and produces steam at a rate of 81.4 at 394 °C and 45.88 bars for an industrial process, via integrating it with concentrated solar power system. In this regard, many simulations have been carried out using Thermoflow software to explore the thermo-economic performance of the gas turbine cogeneration plant integrated with LFR concentrated solar power field. Different electricity

  20. Implicit Particle Filter for Power System State Estimation with Large Scale Renewable Power Integration.

    Science.gov (United States)

    Uzunoglu, B.; Hussaini, Y.

    2017-12-01

    Implicit Particle Filter is a sequential Monte Carlo method for data assimilation that guides the particles to the high-probability by an implicit step . It optimizes a nonlinear cost function which can be inherited from legacy assimilation routines . Dynamic state estimation for almost real-time applications in power systems are becomingly increasingly more important with integration of variable wind and solar power generation. New advanced state estimation tools that will replace the old generation state estimation in addition to having a general framework of complexities should be able to address the legacy software and able to integrate the old software in a mathematical framework while allowing the power industry need for a cautious and evolutionary change in comparison to a complete revolutionary approach while addressing nonlinearity and non-normal behaviour. This work implements implicit particle filter as a state estimation tool for the estimation of the states of a power system and presents the first implicit particle filter application study on a power system state estimation. The implicit particle filter is introduced into power systems and the simulations are presented for a three-node benchmark power system . The performance of the filter on the presented problem is analyzed and the results are presented.

  1. The impact of the CO_2 separation system integration with a 900 MW_e power unit on its thermodynamic and economic indices

    International Nuclear Information System (INIS)

    Łukowicz, Henryk; Mroncz, Marcin

    2015-01-01

    This paper presents an analysis of the thermal cycle of a supercritical 900 MW_e condensing power plant which meets the “capture ready” requirements. The CO_2 separation method selected for the analysis is chemical absorption using MEA (monoethanolamine) or ammonia as sorbent. The indispensable scope of the turbine system upgrade necessitated by the incorporation of the carbon dioxide separation installation is proposed. The change in indices of the power unit operation after integration with the capture installation is presented for different variants of the retrofit. If MEA is used for carbon dioxide separation, the smallest drop in electric power can be observed in the case of hard coal for added stages at the intermediate pressure part outlet. In the case of lignite, the most favourable upgrade solution in terms of the smallest drop in electric power is elimination of one low pressure part and a backpressure turbine is added at the same time. If ammonia is used as sorbent, the best upgrade solution in terms of the smallest drop in electric power is the variant with more stages added at the IP part outlet, regardless of the type of fuel. An economic analysis is conducted for the proposed variants. - Highlights: • Impact of steam extraction on the turbine operation. • Adding more stages at the intermediate pressure part outlet. • Installing a backpressure turbine. • Eliminating one of the operating low pressure parts. • Economic assessment of proposed variants.

  2. Geothermal Exploration By Using Time Domain IP Method:Balikesir (Gure) And Canakkale (Geyikli) Cases From Turkey

    Science.gov (United States)

    Tezel, O.; Ozcep, F.

    2017-12-01

    Geothermal energy is heat derived from the earth. It is the thermal energy contained in the rock and fluid (that fills the fractures and pores within the rock) in the earth's crust. These resources are always at a temperature higher than 20°C. Geothermal energy requires no fuel, and is therefore virtually emission free and independent of fluctuations in fuel cost. Since a geothermal power plant doesn't rely on transient sources of energy, unlike, for example, wind turbines or solar panels, its capacity factor can be quite large. Induced polarization (IP) results at geothermal regions show prominent, extended low resistivity zones. Environmental-IP methods can assist in the assessment of the acid generating potential of waste rock and tailings from mine operations. Resistivity can be used to map contamination plumes. Resistivity and chargeability values were determined using the IP method on geothermal resources in Balikesir Güre (Turkey). In this study we found low resistance values and high chargeability values at the geothermal resource. Finally drilling and IP results were correlated to verify our findings. After the positive results of obtained data, a similar study was carried out in Geyikli Area (Canakkale) and a geothermal resource with 450C temperature of 5 lt/sec was explored at a depth of 970 m.

  3. Equivalent Method of Integrated Power Generation System of Wind, Photovoltaic and Energy Storage in Power Flow Calculation and Transient Simulation

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    The integrated power generation system of wind, photovoltaic (PV) and energy storage is composed of several wind turbines, PV units and energy storage units. The detailed model of integrated generation is not suitable for the large-scale powe.r system simulation because of the model's complexity and long computation time. An equivalent method for power flow calculation and transient simulation of the integrated generation system is proposed based on actual projects, so as to establish the foundation of such integrated system simulation and analysis.

  4. Integration of renewable energies into the German power system and their influence on investments in new power plants. Integrated consideration of effects on power plant investment and operation

    Energy Technology Data Exchange (ETDEWEB)

    Harthan, Ralph Oliver

    2015-01-14

    The increasing share of renewable energies in the power sector influences the economic viability of investments in new conventional power plants. Many studies have investigated these issues by considering power plant operation or the long-term development of the power plant fleet. However, power plant decommissioning, investment and operation are intrinsically linked. This doctoral thesis therefore presents a modelling framework for an integrated consideration of power plant decommissioning, investment and operation. In a case study focusing on Germany, the effects of the integration of renewable energies on power plant decommissioning, investment and operation are evaluated in the context of different assumptions regarding the remaining lifetime of nuclear power plants. With regard to the use of nuclear power, a phase-out scenario and a scenario with lifetime extension of nuclear power plants (by on average 12 years) are considered. The results show that static decommissioning (i.e. considering fixed technical lifetimes) underestimates the capacity available in the power sector in the scenario without lifetime extension since retrofit measures (versus decommissioning) are not taken into account. In contrast, capacity available in the case of nuclear lifetime extension is overestimated since mothballing (versus regular operation) is not considered. If the impact on decommissioning decisions of profit margins accrued during power plant operation are considered (''dynamic decommissioning''), the electricity price reduction effect due to a lifetime extension is reduced by more than half in comparison to static decommissioning. Scarcity situations do not differ significantly between the scenarios with and without lifetime extension with dynamic decommissioning; in contrast, there is a significantly higher need for imports without lifetime extension with static decommissioning. The case study demonstrates that further system flexibility is needed for

  5. Integration of renewable energies into the German power system and their influence on investments in new power plants. Integrated consideration of effects on power plant investment and operation

    International Nuclear Information System (INIS)

    Harthan, Ralph Oliver

    2015-01-01

    The increasing share of renewable energies in the power sector influences the economic viability of investments in new conventional power plants. Many studies have investigated these issues by considering power plant operation or the long-term development of the power plant fleet. However, power plant decommissioning, investment and operation are intrinsically linked. This doctoral thesis therefore presents a modelling framework for an integrated consideration of power plant decommissioning, investment and operation. In a case study focusing on Germany, the effects of the integration of renewable energies on power plant decommissioning, investment and operation are evaluated in the context of different assumptions regarding the remaining lifetime of nuclear power plants. With regard to the use of nuclear power, a phase-out scenario and a scenario with lifetime extension of nuclear power plants (by on average 12 years) are considered. The results show that static decommissioning (i.e. considering fixed technical lifetimes) underestimates the capacity available in the power sector in the scenario without lifetime extension since retrofit measures (versus decommissioning) are not taken into account. In contrast, capacity available in the case of nuclear lifetime extension is overestimated since mothballing (versus regular operation) is not considered. If the impact on decommissioning decisions of profit margins accrued during power plant operation are considered (''dynamic decommissioning''), the electricity price reduction effect due to a lifetime extension is reduced by more than half in comparison to static decommissioning. Scarcity situations do not differ significantly between the scenarios with and without lifetime extension with dynamic decommissioning; in contrast, there is a significantly higher need for imports without lifetime extension with static decommissioning. The case study demonstrates that further system flexibility is needed for

  6. Voice over IP in the Local Exchange: A Case Study

    OpenAIRE

    Weiss, Martin B. H.; Kim, Hak-Ju

    2001-01-01

    There have been a small number of cost studies of Voice over IP (VoIP) in the academic literature. Generally, they have been for abstract networks, have not been focused on the public switched telephone network, or they have not included the operating costs. This paper presents the operating cost portion of our ongoing research project comparing circuit-switched and IP network costs for an existing local exchange carrier. We have found that (1) The operating cost differential between IP and c...

  7. Integration trends in monolithic power ICs: Application and technology challenges

    NARCIS (Netherlands)

    Rose, M.; Bergveld, H.J.

    2016-01-01

    This paper highlights the general trend towards further monolithic integration in power applications by enabling power management and interfacing solutions in advanced CMOS nodes. The need to combine high-density digital circuits, power-management circuits, and robust interfaces in a single

  8. Security Risks in IP Telephony

    Directory of Open Access Journals (Sweden)

    Filip Rezac

    2010-01-01

    Full Text Available This paper deals with VoIP communication security and various techniques of VoIP attacks. We divided these threats in several categories according to their specific behaviour and their impact on the affected system. We also tried to find effective methods to prevent or mitigate these attacks. We focused our work on Spam over Internet Telephony (SPIT as a real threat for the future. We have developed both a tool generating SPIT attacks and AntiSPIT tool defending communication systems against SPIT attacks. AntiSPIT represents an effective protection based on statistical blacklist and works without participation of the called party which is a significant advantage.

  9. Comparison of performance between TCP/IP over ATM e ATM nativo

    OpenAIRE

    Marcelo Silva Freitas

    2001-01-01

    Com o recente desenvolvimento de tecnologias de redes de altas taxas de transmissão, tais como Asynchronous Transfer Mode (ATM), o problema da carência por largura de banda foi solucionado. A questão atual é a implementação de sistemas que suportem os protocolos ATM de forma nativa e integral. Atualmente tem-se utilizado aplicativos tradicionais baseados nos protocolos TCP(UDP)/IP no topo da pilha de protocolos ATM. Tal modelo traz redundâncias que implicam diretamente em aumento de overhead ...

  10. Generator Rescheduling under Congested Power System with Wind Integrated Competitive Power Market

    Directory of Open Access Journals (Sweden)

    Sadhan Gope

    2017-02-01

    Full Text Available Integration of renewable energy like wind or solar energy creates a huge pressure to the system operator (SO to ensure the congestion free transmission network under deregulated power market. Congestion Management (CM with integration of wind farm in double auction electricity market are described in this work to minimize fuel cost, system losses and locational marginal price (LMP of the system. Location of Wind Farm (WF is identified based by using Bus sensitivity factor (BSF, which is also used for selection of load bus for double auction bidding (DAB. The impacts of wind farm in congested power system under deregulated environment have been investigated in this work. Modified 39-bus New England test system is used for demonstrate the effectiveness of the presented approach by using Sequential Quadratic Programming (SQP.

  11. Integrated systems for power plant cooling and wastewater management

    International Nuclear Information System (INIS)

    Haith, D.A.

    1975-01-01

    The concept of integrated management of energy and water resources, demonstrated in hydropower development, may be applicable to steam-generated power, also. For steam plants water is a means of disposing of a waste product, which is unutilized energy in the form of heat. One framework for the evolution of integrated systems is the consideration of possible technical linkages between power plant cooling and municipal wastewater management. Such linkages include the use of waste heat as a mechanism for enhancing wastewater treatment, the use of treated wastewater as make-up for evaporative cooling structures, and the use of a pond or reservoir for both cooling and waste stabilization. This chapter reports the results of a systematic evaluation of possible integrated systems for power plant cooling and waste water management. Alternatives were analyzed for each of three components of the system--power plant cooling (condenser heat rejection), thermally enhanced waste water treatment, and waste water disposal. Four cooling options considered were evaporative tower, open cycle, spray pond, and cooling pond. Three treatment alternatives considered were barometric condenser-activated sludge, sectionalized condenser-activated sludge, and cooling/stabilization pond. Three disposal alternatives considered were ocean discharge, land application (spray irrigation), and make-up (for evaporative cooling). To facilitate system comparisons, an 1100-MW nuclear power plant was selected. 31 references

  12. Ade-Ojo, IP

    African Journals Online (AJOL)

    Ade-Ojo, IP. Vol 40, No 2 (2013) - Articles Myasthenia gravis following chicken pox infection in a Nigerian primary school girl. Abstract PDF. ISSN: 0302-4660. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions ...

  13. A 39-kD plasma membrane protein (IP39) is an anchor for the unusual membrane skeleton of Euglena gracilis

    International Nuclear Information System (INIS)

    Rosiere, T.K.; Marrs, J.A.; Bouck, G.B.

    1990-01-01

    The major integral plasma membrane protein (IP39) of Euglena gracilis was radiolabeled, peptide mapped, and dissected with proteases to identify cytoplasmic domains that bind and anchor proteins of the cell surface. When plasma membranes were radioiodinated and extracted with octyl glucoside, 98% of the extracted label was found in IP39 or the 68- and 110-kD oligomers of IP39. The octyl glucoside extracts were incubated with unlabeled cell surface proteins immobilized on nitrocellulose (overlays). Radiolabel from the membrane extract bound one (80 kD) of the two (80 and 86 kD) major membrane skeletal protein bands. Resolubilization of the bound label yielded a radiolabeled polypeptide identical in Mr to IP39. Intact plasma membranes were also digested with papain before or after radioiodination, thereby producing a cytoplasmically truncated IP39. The octyl glucoside extract of truncated IP39 no longer bound to the 80-kD membrane skeletal protein in the nitrocellulose overlays. EM of intact or trypsin digested plasma membranes incubated with membrane skeletal proteins under stringent conditions similar to those used in the nitrocellulose overlays revealed a partially reformed membrane skeletal layer. Little evidence of a membrane skeletal layer was found, however, when plasma membranes were predigested with papain before reassociation. A candidate 80-kD binding domain of IP39 has been tentatively identified as a peptide fragment that was present after trypsin digestion of plasma membranes, but was absent after papain digestion in two-dimensional peptide maps of IP39. Together, these data suggest that the unique peripheral membrane skeleton of Euglena binds to the plasma membrane through noncovalent interactions between the major 80-kD membrane skeletal protein and a small, papain sensitive cytoplasmic domain of IP39

  14. Mobile location services over the next generation IP core network

    DEFF Research Database (Denmark)

    Thongthammachart, Saowanee; Olesen, Henning

    2003-01-01

    network is changing from circuit-switched to packet-switched technology and evolving to an IP core network based on IPv6. The IP core network will allow all IP devices to be connected seamlessly. Due to the movement detection mechanism of Mobile IPv6, mobile terminals will periodically update....... The concept of mobile location services over the next generation IP networks is described. We also discuss the effectiveness of the short-range wireless network regarding a mobile user's position inside buildings and hotspot areas....

  15. Sliding mode load frequency control for multi-area time-delay power system with wind power integration

    DEFF Research Database (Denmark)

    Mi, Yang; Hao, Xuezhi; Liu, Yongjuan

    2017-01-01

    The interconnected time-delay power system has become an important issue for the open communication network. Meanwhile, due to the output power fluctuation of integrated wind energy, load frequency control (LFC) for power system with variable sources and loads has become more complicated. The novel...

  16. IPS Empress inlays luted with a self-adhesive resin cement after 1 year.

    Science.gov (United States)

    Taschner, Michael; Frankenberger, Roland; García-Godoy, Franklin; Rosenbusch, Silke; Petschelt, Anselm; Krämer, Norbert

    2009-02-01

    To prospectively compare the clinical performance of two different resin composites for luting IPS Empress inlays and onlays. 83 IPS Empress restorations were placed in 30 subjects. All restorations were inserted under rubber dam. 43 inlays/onlays were luted with a self-adhesive resin cement [RelyX Unicem (RX)]. A multistep adhesive (Syntac) was used with Variolink II low viscosity (SV) and served as control (n=40). The restorations were evaluated after 2 weeks: Baseline = 1st recall (R1), after 6 months (R2) and after 1 year (R3) by two calibrated examiners using the modified USPHS criteria. From R1 to R3, one failure was noticed in the SV group (R2) due to marginal enamel chipping. After 1 year of clinical service, SV revealed significantly better results regarding color match and integrity inlay (Mann-Whitney U-test, P0.05).

  17. Low Power Consumption Wireless Sensor Communication System Integrated with an Energy Harvesting Power Source

    OpenAIRE

    Vlad MARSIC; Alessandro GIULIANO; Meiling ZHU

    2013-01-01

    This paper presents the testing results of a wireless sensor communication system with low power consumption integrated with an energy harvesting power source. The experiments focus on the system’s capability to perform continuous monitoring and to wirelessly transmit the data acquired from the sensors to a user base station, for realization of completely battery-free wireless sensor system. Energy harvesting technologies together with system design optimization for power consumption minimiza...

  18. Uniform decrease of alpha-global field power induced by intermittent photic stimulation of healthy subjects

    Directory of Open Access Journals (Sweden)

    Rau R.

    2002-01-01

    Full Text Available Nineteen-channel EEGs were recorded from the scalp surface of 30 healthy subjects (16 males and 14 females, mean age: 34 years, SD: 11.7 years at rest and under trains of intermittent photic stimulation (IPS at rates of 5, 10 and 20 Hz. Digitalized data were submitted to spectral analysis with fast fourier transformation providing the basis for the computation of global field power (GFP. For quantification, GFP values in the frequency ranges of 5, 10 and 20 Hz at rest were divided by the corresponding data obtained under IPS. All subjects showed a photic driving effect at each rate of stimulation. GFP data were normally distributed, whereas ratios from photic driving effect data showed no uniform behavior due to high interindividual variability. Suppression of alpha-power after IPS with 10 Hz was observed in about 70% of the volunteers. In contrast, ratios of alpha-power were unequivocal in all subjects: IPS at 20 Hz always led to a suppression of alpha-power. Dividing alpha-GFP with 20-Hz IPS by alpha-GFP at rest (R = alpha-GFP IPS/alpha-GFPrest thus resulted in ratios lower than 1. We conclude that ratios from GFP data with 20-Hz IPS may provide a suitable paradigm for further investigations.

  19. Development of a type IP-2 freight container and leak testing during the longitudinal and transverse racking tests

    International Nuclear Information System (INIS)

    Holden, G.V.

    2002-01-01

    The leak performance of freight containers has never been particularly well defined within the UK and up to the publication of 'A DETR guide to the approval of freight containers as IP-2 and IP-3 packages' freight containers with twin rear doors were acceptable as IP-2/3 packages. The containment argument has usually been based on providing adequate load securing and transport under exclusive use (with no transhipment between modes). Hence the likelihood for dropping the freight container during transhipment is eliminated. These arguments are less acceptable to competent authorities and the document above requires that leak integrity is determined during the standard freight container tests. This paper outlines the methodology used to determine the acceptable leak rate from the container (in terms of a pressure drop); the justification for conducting leak testing during racking only; the results of tests and difficulties that were overcome during design. (author)

  20. Incentives and barriers for wind power expansion and system integration in Denmark

    DEFF Research Database (Denmark)

    Hvelplund, Frede; Ostergaard, Poul Alberg; Meyer, Niels I

    2017-01-01

    In Denmark expansion of on-shore, near-shore and off-shore wind power is planned to increase the wind power share to 50% of electricity consumption by 2020. In this situation a continuation of past policies will not suffice, and a dual-track incentive system that both establishes incentives...... for investing in wind power and integration infrastructure with integration between the electricity, heating and transportation sectors, is required. The current Danish taxation system discourages electricity use and works against this integration. Likewise, the current day-ahead electricity spot market...... is not appropriate for a high-wind future as wind reduces price levels, but integration across sectors can partly assist in increasing demand and prices. The European Emission Trading System does not suffice in providing a level playing field for wind power and thus needs a revision. Another barrier for on...

  1. Multi-gigabit low-power radiation-tolerant data links and improved data motion in trackers

    International Nuclear Information System (INIS)

    Miller, M; Brewer, F; Wang, D; Magazzu, G

    2014-01-01

    We present a set of links based on data-transmission IP in 130nm designed for rapid integration into ASIC designs. These links are designed for use in very high radiation environments as occur in high energy physics experiments. The designs are additionally low power and small area, easing integration with other electronic systems. These links are well suited to use in tracking detectors. Trackers, due to their close proximity to the collision, are subject to very high levels of radiation, and hence require such radiation hardened electronics. The portfolio of radiation hardened data transmission blocks consists of a 1Gbps serializer/deserializer with a very low power consumption ∼ 1mW for each. A differential transmitter and differential receiver rated at 3GHz, both designed to be much faster than needed, as insurance against radiation damage. Finally, the impact of a prototype low-latency, low-power ( < 60mW total link power) 5Gbps link is considered. Case analysis of the impacts of using lower powered, higher speed blocks in hypothetical trackers is studied, showing power improvements relative to alternative technologies

  2. Biobjective VoIP Service Management in Cloud Infrastructure

    Directory of Open Access Journals (Sweden)

    Jorge M. Cortés-Mendoza

    2016-01-01

    Full Text Available Voice over Internet Protocol (VoIP allows communication of voice and/or data over the internet in less expensive and reliable manner than traditional ISDN systems. This solution typically allows flexible interconnection between organization and companies on any domains. Cloud VoIP solutions can offer even cheaper and scalable service when virtualized telephone infrastructure is used in the most efficient way. Scheduling and load balancing algorithms are fundamental parts of this approach. Unfortunately, VoIP scheduling techniques do not take into account uncertainty in dynamic and unpredictable cloud environments. In this paper, we formulate the problem of scheduling of VoIP services in distributed cloud environments and propose a new model for biobjective optimization. We consider the special case of the on-line nonclairvoyant dynamic bin-packing problem and discuss solutions for provider cost and quality of service optimization. We propose twenty call allocation strategies and evaluate their performance by comprehensive simulation analysis on real workload considering six months of the MIXvoip company service.

  3. Limitations and possibilities of low cell number ChIP-seq

    Directory of Open Access Journals (Sweden)

    Gilfillan Gregor D

    2012-11-01

    Full Text Available Abstract Background Chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq offers high resolution, genome-wide analysis of DNA-protein interactions. However, current standard methods require abundant starting material in the range of 1–20 million cells per immunoprecipitation, and remain a bottleneck to the acquisition of biologically relevant epigenetic data. Using a ChIP-seq protocol optimised for low cell numbers (down to 100,000 cells / IP, we examined the performance of the ChIP-seq technique on a series of decreasing cell numbers. Results We present an enhanced native ChIP-seq method tailored to low cell numbers that represents a 200-fold reduction in input requirements over existing protocols. The protocol was tested over a range of starting cell numbers covering three orders of magnitude, enabling determination of the lower limit of the technique. At low input cell numbers, increased levels of unmapped and duplicate reads reduce the number of unique reads generated, and can drive up sequencing costs and affect sensitivity if ChIP is attempted from too few cells. Conclusions The optimised method presented here considerably reduces the input requirements for performing native ChIP-seq. It extends the applicability of the technique to isolated primary cells and rare cell populations (e.g. biobank samples, stem cells, and in many cases will alleviate the need for cell culture and any associated alteration of epigenetic marks. However, this study highlights a challenge inherent to ChIP-seq from low cell numbers: as cell input numbers fall, levels of unmapped sequence reads and PCR-generated duplicate reads rise. We discuss a number of solutions to overcome the effects of reducing cell number that may aid further improvements to ChIP performance.

  4. Wind power integration into the automatic generation control of power systems with large-scale wind power

    Directory of Open Access Journals (Sweden)

    Abdul Basit

    2014-10-01

    Full Text Available Transmission system operators have an increased interest in the active participation of wind power plants (WPP in the power balance control of power systems with large wind power penetration. The emphasis in this study is on the integration of WPPs into the automatic generation control (AGC of the power system. The present paper proposes a coordinated control strategy for the AGC between combined heat and power plants (CHPs and WPPs to enhance the security and the reliability of a power system operation in the case of a large wind power penetration. The proposed strategy, described and exemplified for the future Danish power system, takes the hour-ahead regulating power plan for generation and power exchange with neighbouring power systems into account. The performance of the proposed strategy for coordinated secondary control is assessed and discussed by means of simulations for different possible future scenarios, when wind power production in the power system is high and conventional production from CHPs is at a minimum level. The investigation results of the proposed control strategy have shown that the WPPs can actively help the AGC, and reduce the real-time power imbalance in the power system, by down regulating their production when CHPs are unable to provide the required response.

  5. Secure IP mobility management for VANET

    CERN Document Server

    Taha, Sanaa

    2013-01-01

    This brief presents the challenges and solutions for VANETs' security and privacy problems occurring in mobility management protocols including Mobile IPv6 (MIPv6), Proxy MIPv6 (PMIPv6), and Network Mobility (NEMO). The authors give an overview of the concept of the vehicular IP-address configurations as the prerequisite step to achieve mobility management for VANETs, and review the current security and privacy schemes applied in the three mobility management protocols. Throughout the brief, the authors propose new schemes and protocols to increase the security of IP addresses within VANETs in

  6. Best Practices: Power Quality and Integrated Testing at JSC

    Science.gov (United States)

    Davis, Lydia

    2018-01-01

    This presentation discusses Best Practices for Power Quality and Integrated Testing at JSC in regards to electrical systems. These high-level charts include mostly generic information; however, a specific issue is discussed involving flight hardware that could have been discovered prior to flight with an integrated test.

  7. Secure Protocol and IP Core for Configuration of Networking Hardware IPs in the Smart Grid

    Directory of Open Access Journals (Sweden)

    Marcelo Urbina

    2018-02-01

    Full Text Available Nowadays, the incorporation and constant evolution of communication networks in the electricity sector have given rise to the so-called Smart Grid, which is why it is necessary to have devices that are capable of managing new communication protocols, guaranteeing the strict requirements of processing required by the electricity sector. In this context, intelligent electronic devices (IEDs with network architectures are currently available to meet the communication, real-time processing and interoperability requirements of the Smart Grid. The new generation IEDs include an Field Programmable Gate Array (FPGA, to support specialized networking switching architectures for the electric sector, as the IEEE 1588-aware High-availability Seamless Redundancy/Parallel Redundancy Protocol (HSR/PRP. Another advantage to using an FPGA is the ability to update or reconfigure the design to support new requirements that are being raised to the standards (IEC 61850. The update of the architecture implemented in the FPGA can be done remotely, but it is necessary to establish a cyber security mechanism since the communication link generates vulnerability in the case the attacker gains physical access to the network. The research presented in this paper proposes a secure protocol and Intellectual Property (IP core for configuring and monitoring the networking IPs implemented in a Field Programmable Gate Array (FPGA. The FPGA based implementation proposed overcomes this issue using a light Layer-2 protocol fully implemented on hardware and protected by strong cryptographic algorithms (AES-GCM, defined in the IEC 61850-90-5 standard. The proposed secure protocol and IP core are applicable in any field where remote configuration over Ethernet is required for IP cores in FPGAs. In this paper, the proposal is validated in communications hardware for Smart Grids.

  8. Intellectual Property and Strategic Agreements (IP/SA) | FNLCR Staging

    Science.gov (United States)

    IP/SA handles all invention issues including patents and copyrights. All employee inventionreports are filed through the IP/SA office for all activities under the OTS contract.Additionally,request for assignment ofcopyri

  9. Prognostic value of CtIP/RBBP8 expression in breast cancer

    International Nuclear Information System (INIS)

    Soria-Bretones, Isabel; Sáez, Carmen; Ruíz-Borrego, Manuel; Japón, Miguel A; Huertas, Pablo

    2013-01-01

    CtIP/RBBP8 is a multifunctional protein involved in transcription, DNA replication, DNA repair by homologous recombination and the G1 and G2 checkpoints. Its multiple roles are controlled by its interaction with several specific factors, including the tumor suppressor proteins BRCA1 and retinoblastoma. Both its functions and interactors point to a putative oncogenic potential of CtIP/RBBP8 loss. However, CtIP/RBBP8 relevance in breast tumor appearance, development, and prognosis has yet to be established. We performed a retrospective analysis of CtIP/RBBP8 and RB1 levels by immunohistochemistry using 384 paraffin-embedded breast cancer biopsies obtained during tumor removal surgery. We have observed that low or no expression of CtIP/RBBP8 correlates with high-grade breast cancer and with nodal metastasis. Reduction on CtIP/RBBP8 is most common in hormone receptor (HR)-negative, HER2-positive, and basal-like tumors. We observed lower levels of RB1 on those tumors with reduced CtIP/RBBP8 levels. On luminal tumors, decreased but not absence of CtIP/RBBP8 levels correlate with increased disease-free survival when treated with a combination of hormone, radio, and chemo therapies

  10. Integration of Renewable Generation in Power System Defence Plans

    DEFF Research Database (Denmark)

    Das, Kaushik

    Increasing levels of penetration of wind power and other renewable generations in European power systems pose challenges to power system security. The power system operators are continuously challenged especially when generations from renewables are high thereby reducing online capacity of conven......Increasing levels of penetration of wind power and other renewable generations in European power systems pose challenges to power system security. The power system operators are continuously challenged especially when generations from renewables are high thereby reducing online capacity......, one of them being the North East area with high share of wind power generation.The aim of this study is to investigate how renewable generations like wind power can contribute to the power system defence plans. This PhD project “Integration of Renewable Generation in Power System Defence Plans...

  11. China's Indigenous IP Policies -- Here to Stay?

    OpenAIRE

    Prud'homme, Dan

    2013-01-01

    In 2010 and 2011, foreign businesses and governments welcomed measures believed to dramatically reform a highly controversial branch of China’s indigenous innovation policy which provided government procurement preferences to applicants who can meet restrictive indigenous intellectual property (IP) rights requirements. However, this article describes specific examples of (what can be labeled) China’s “indigenous IP policy” that are still very much in force, in particular several programs link...

  12. CMOS analog integrated circuits high-speed and power-efficient design

    CERN Document Server

    Ndjountche, Tertulien

    2011-01-01

    High-speed, power-efficient analog integrated circuits can be used as standalone devices or to interface modern digital signal processors and micro-controllers in various applications, including multimedia, communication, instrumentation, and control systems. New architectures and low device geometry of complementary metaloxidesemiconductor (CMOS) technologies have accelerated the movement toward system on a chip design, which merges analog circuits with digital, and radio-frequency components. CMOS: Analog Integrated Circuits: High-Speed and Power-Efficient Design describes the important tren

  13. 9{sup th} international workshop on large-scale integration of wind power into power systems as well as on transmission networks for offshore wind power plants. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Betancourt, Uta; Ackermann, Thomas (eds.)

    2010-07-01

    Within the 9th International Workshop on large-scale integration of wind power into power systems as well as on transmission networks for offshore wind power plants at 18th to 19th October, 2010 in Quebec (Canada), lectures and poster papers were presented to the following themes: (1) Keynote session and panel; (2) European grid integration studies; (3) Modeling; (4) Wind forecasting; (5) North American grid integration studies; (6) Voltage stability and control; (7) Grid codes and impact studies; (8) Canadian University research (WESNet); (9) Operation and dispatch; (9) Offshore wind power plants; (10) Frequency Control; (11) Methodologies to estimate wind power impacts on power systems, summaries from IEAWIND collaboration; (12) HVDC; (13) Grid codes and system impact studies; (14) Modeling and validation; (15) Regulations, markets and offshore wind energy; (16) Integration issues; (17) Wind turbine control system; (18) Energy management and IT solutions.

  14. Internetiside VoIP sobib ka ettevõtteile / Valdur Laid

    Index Scriptorium Estoniae

    Laid, Valdur, 1969-

    2005-01-01

    Ilmunud ka: Delovõje Vedomosti 8. juuni lk. 19. Kommunikatsiooni liikumisest internetti ehk IP-võrku ning selle võimalustest ettevõtjaile. Vt. samas: Väikefirmade IP-lahendus jõuab aasta lõpus massturule

  15. Grid Code Requirements for Wind Power Integration

    DEFF Research Database (Denmark)

    Wu, Qiuwei

    2018-01-01

    This chapter reviews the grid code requirements for integration of wind power plants (WPPs). The grid codes reviewed are from the UK, Ireland, Germany, Denmark, Spain, Sweden, the USA, and Canada. Transmission system operators (TSOs) around the world have specified requirements for WPPs under...

  16. A hierarchical clustering scheme approach to assessment of IP-network traffic using detrended fluctuation analysis

    Science.gov (United States)

    Takuma, Takehisa; Masugi, Masao

    2009-03-01

    This paper presents an approach to the assessment of IP-network traffic in terms of the time variation of self-similarity. To get a comprehensive view in analyzing the degree of long-range dependence (LRD) of IP-network traffic, we use a hierarchical clustering scheme, which provides a way to classify high-dimensional data with a tree-like structure. Also, in the LRD-based analysis, we employ detrended fluctuation analysis (DFA), which is applicable to the analysis of long-range power-law correlations or LRD in non-stationary time-series signals. Based on sequential measurements of IP-network traffic at two locations, this paper derives corresponding values for the LRD-related parameter α that reflects the degree of LRD of measured data. In performing the hierarchical clustering scheme, we use three parameters: the α value, average throughput, and the proportion of network traffic that exceeds 80% of network bandwidth for each measured data set. We visually confirm that the traffic data can be classified in accordance with the network traffic properties, resulting in that the combined depiction of the LRD and other factors can give us an effective assessment of network conditions at different times.

  17. Anticipation of Traffic Demands to Guarantee QoS in IP/Optical Networks

    Directory of Open Access Journals (Sweden)

    Carolina Pinart

    2010-09-01

    Full Text Available Traffic in the Internet backbone is expected to grow above a few Tbit/s in 2020. To cope with this, operators are moving to IP/optical network architectures, where IP is the convergence layer for all services. On the other hand, the quality of service (QoS requirements of future applications encompasses the individualization of services and the assurance of stricter quality parameters such as latency, jitter or capacity. In other words, future optical networks will not only transport more IP data, but they will also have to offer differentiated QoS requirements to services. Finally, some emerging applications, e.g., grid computing, need greater flexibility in the usage of network resources, which involves establishing and releasing connections as if they were virtualized resources controlled by other elements or layers. In this context, traffic-driven lightpath provisioning and service-plane approaches arise as very interesting candidate solutions to solve the main challenges described above. This work reviews the concepts of service-oriented and self-managed networks and relates them to propose an integrated approach to assure QoS by offering flow-aware networking in the sense that traffic demands will be anticipated in a suitable way, lightpaths will be established taking into account QoS information (i.e., impairments and complex services will be decomposed into optical connections so that the above techniques can be employed to assure QoS for any service.

  18. All-IP-Ethernet architecture for real-time sensor-fusion processing

    Science.gov (United States)

    Hiraki, Kei; Inaba, Mary; Tezuka, Hiroshi; Tomari, Hisanobu; Koizumi, Kenichi; Kondo, Shuya

    2016-03-01

    Serendipter is a device that distinguishes and selects very rare particles and cells from huge amount of population. We are currently designing and constructing information processing system for a Serendipter. The information processing system for Serendipter is a kind of sensor-fusion system but with much more difficulties: To fulfill these requirements, we adopt All IP based architecture: All IP-Ethernet based data processing system consists of (1) sensor/detector directly output data as IP-Ethernet packet stream, (2) single Ethernet/TCP/IP streams by a L2 100Gbps Ethernet switch, (3) An FPGA board with 100Gbps Ethernet I/F connected to the switch and a Xeon based server. Circuits in the FPGA include 100Gbps Ethernet MAC, buffers and preprocessing, and real-time Deep learning circuits using multi-layer neural networks. Proposed All-IP architecture solves existing problem to construct large-scale sensor-fusion systems.

  19. IP EUROTRANS: from MYRRHA towards XT-ADS

    International Nuclear Information System (INIS)

    Debruyn, D.

    2006-01-01

    The integrated project (IP) EUROTRANS (EUROpean Research Programme for the TRANSmutation of High-Level Nuclear Waste in an Accelerator Driven System) has been launched in the Euratom Sixth Framework Programme (FP6) and has officially started in April 2005 for a duration of four years. This project is the logical continuation of several activities worked out within the previous Framework Programme (FP5), namely the ADOPT network, the FUETRA, BASTRA and TESTRA clusters and the PDS-XADS project. The project is divided into five main sub-projects or domains (DMs). SCK-CEN coordinates the DM1 DESIGN described hereafter. The aim of DM2 ECATS is to provide validated experimental input from relevant coupling experiments of an accelerator, a spallation target and a sub-critical blanket, while the development and demonstration of the associated technologies is devoted to the remaining DMs, DM3 AFTRA (fuels), DM4 DEMETRA (heavy liquid metal technologies) and DM5 NUDATRA (nuclear data). The objective of the DM1 DESIGN of IP EUROTRANS is to proceed by a significant jump towards the demonstration of the industrial transmutation through the ADS route. The strategy of European Transmutation Demonstration (ETD) is carried out with two interconnected activities: (1) the first activity is to develop an advanced design file leading to a short-term (i.e. realisation within the next 10 years) experimental demonstration of the technical feasibility of Transmutation (at 50 to 100 MWth) in an Accelerator Driven System (XT-ADS). Liquid lead-bismuth eutectic (LBE) is used as primary coolant and material for the spallation target and the core is designed with standard MOX fuel; (2) the second activity is to carry out in parallel a reference conceptual design for a modular EFIT (European Facility for Industrial Transmutation) machine with a power of up to several 100 MWth, as a basis for a cost estimate and safety studies for an ADS-based transmutation system. For the EFIT, liquid lead is used

  20. Unjuk Kerja IP PBX Asterisk dan FreeSWITCH pada Topologi Bertingkat di Jaringan Kampus

    Directory of Open Access Journals (Sweden)

    Iwan Setiawan

    2017-08-01

    Full Text Available Internet Protocol-based Private Branch Exchange (IP PBX diperlukan untuk menghubungkan panggilan antar perangkat komunikasi Voice over Internet Protocol (VoIP di sebuah jaringan lokal (LAN. Dengan adanya IP PBX, layanan VoIP dapat disediakan di atas jaringan data/IP yang sudah tergelar. Penelitian ini kami lakukan untuk mengetahui unjuk kerja VoIP pada dua IP PBX yang menggunakan perangkat lunak server Asterisk dan FreeSWITCH. Kami merancang sebuah arsitektur jaringan eksperimen yang diadaptasi dari topologi bertingkat pada jaringan kampus (CAN di lokasi penelitian dengan hierarki perangkat yang terdiri dari core switch, distribution switch, dan access switch. Kedua IP PBX ditempatkan pada hierarki yang berbeda pada topologi jaringan tersebut agar dapat diketahui pengaruhnya terhadap unjuk kerja VoIP. Konsep eksperimen ini diharapkan dapat menjadi salah satu dasar untuk mendesain arsitektur IP PBX secara terpusat dan tersebar pada jaringan kampus. Unjuk kerja VoIP kami ukur dengan parameter-parameter Quality of Service (QoS dan Quality of Experience (QoE. Selain itu, kami juga mengukur konsumsi prosesor dan memori yang dipakai oleh perangkat lunak server VoIP pada saat komunikasi terjadi. Pengukuran dilakukan dengan skenario phone-to-phone pada jaringan eksperimen yang terhubung ke jaringan kampus aktif. Hasil penelitian menunjukkan bahwa penempatan IP PBX di hierarki yang berbeda pada topologi jaringan berpengaruh terhadap unjuk kerja VoIP khususnya pada IP PBX Asterisk. Ketika dibandingkan, unjuk kerja IP PBX FreeSWITCH dalam hal QoS dan QoE sedikit lebih baik daripada Asterisk pada rerata latensi/delay, jitter, Mean Opinion Score (MOS, dan konsumsi memori yaitu 41,012 ms, 0,060 ms, 5, dan 1 % untuk IP PBX 1 serta 41,016 ms, 0,066 ms, 5, dan 0,5 % untuk IP PBX 2

  1. 76 FR 69284 - Certain Integrated Solar Power Systems and Components Thereof: Notice of Institution of...

    Science.gov (United States)

    2011-11-08

    ... the United States after importation of certain integrated solar power systems and components thereof... certain integrated solar power systems and components thereof that infringe one or more of claims 6 and 10... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-811] Certain Integrated Solar Power...

  2. Voice over IP phone calls from your smartphone

    CERN Multimedia

    2014-01-01

    All CERN users do have a Lync account (see here) and can use Instant Messaging, presence and other features. In addition, if your number is activated on Lync IP Phone(1) system then you can make standard phone calls from your computer (Windows/Mac).   Recently, we upgraded the infrastructure to Lync 2013. One of the major features is the possibility to make Voice over IP phone calls from a smartphone using your CERN standard phone number (not mobile!). Install Lync 2013 on iPhone/iPad, Android or Windows Phone, connect to WiFi network and make phone calls as if you were in your office. There will be no roaming charges because you will be using WiFi to connect to CERN phone system(2). Register here to the presentation on Tuesday 29 April at 11 a.m. in the Technical Training Center and see the most exciting features of Lync 2013.   Looking forward to seeing you! The Lync team (1) How to register on Lync IP Phone system: http://information-technology.web.cern.ch/book/lync-ip-phone-serv...

  3. Validation of the Spanish version of the Irrational Procrastination Scale (IPS.

    Directory of Open Access Journals (Sweden)

    Georgina Guilera

    Full Text Available The present study is centered in adapting and validating a Spanish version of the Irrational Procrastination Scale (IPS. The sample consists of 365 adults aged 18-77 years (M = 37.70, SD = 12.64. Participants were administered two measures of procrastination, the IPS and the Decisional Procrastination Questionnaire, as well as the Big Five Inventory, and the Satisfaction With Life Scale. First, the factor and replication analysis revealed that the internal structure of the scale is clearly one-dimensional, supporting the idea that IPS seems to measure general procrastination as a single trait. Second, the internal consistency is satisfactory as is the temporal stability of the IPS scores. Third, the correlations encountered between the IPS scores and other measures of procrastination, personality traits and satisfaction with life are all in the expected direction and magnitude. Finally, consistent with previous research, procrastination is related to age, with the youngest being the most procrastinating group. This study represents the first attempt in adapting and validating the IPS measure of procrastination into Spanish. Results suggest that the Spanish version of the IPS offers valid and reliable scores when applied to adult population.

  4. Validation of the Spanish version of the Irrational Procrastination Scale (IPS)

    Science.gov (United States)

    Guilera, Georgina; Penelo, Eva; Morin, Christopher; Steel, Piers; Gómez-Benito, Juana

    2018-01-01

    The present study is centered in adapting and validating a Spanish version of the Irrational Procrastination Scale (IPS). The sample consists of 365 adults aged 18–77 years (M = 37.70, SD = 12.64). Participants were administered two measures of procrastination, the IPS and the Decisional Procrastination Questionnaire, as well as the Big Five Inventory, and the Satisfaction With Life Scale. First, the factor and replication analysis revealed that the internal structure of the scale is clearly one-dimensional, supporting the idea that IPS seems to measure general procrastination as a single trait. Second, the internal consistency is satisfactory as is the temporal stability of the IPS scores. Third, the correlations encountered between the IPS scores and other measures of procrastination, personality traits and satisfaction with life are all in the expected direction and magnitude. Finally, consistent with previous research, procrastination is related to age, with the youngest being the most procrastinating group. This study represents the first attempt in adapting and validating the IPS measure of procrastination into Spanish. Results suggest that the Spanish version of the IPS offers valid and reliable scores when applied to adult population. PMID:29304119

  5. Validation of the Spanish version of the Irrational Procrastination Scale (IPS).

    Science.gov (United States)

    Guilera, Georgina; Barrios, Maite; Penelo, Eva; Morin, Christopher; Steel, Piers; Gómez-Benito, Juana

    2018-01-01

    The present study is centered in adapting and validating a Spanish version of the Irrational Procrastination Scale (IPS). The sample consists of 365 adults aged 18-77 years (M = 37.70, SD = 12.64). Participants were administered two measures of procrastination, the IPS and the Decisional Procrastination Questionnaire, as well as the Big Five Inventory, and the Satisfaction With Life Scale. First, the factor and replication analysis revealed that the internal structure of the scale is clearly one-dimensional, supporting the idea that IPS seems to measure general procrastination as a single trait. Second, the internal consistency is satisfactory as is the temporal stability of the IPS scores. Third, the correlations encountered between the IPS scores and other measures of procrastination, personality traits and satisfaction with life are all in the expected direction and magnitude. Finally, consistent with previous research, procrastination is related to age, with the youngest being the most procrastinating group. This study represents the first attempt in adapting and validating the IPS measure of procrastination into Spanish. Results suggest that the Spanish version of the IPS offers valid and reliable scores when applied to adult population.

  6. ELISA-based assay for IP-10 detection from filter paper samples

    DEFF Research Database (Denmark)

    Drabe, Camilla Heldbjerg; Blauenfeldt, Thomas; Ruhwald, Morten

    2014-01-01

    IP-10 is a small pro-inflammatory chemokine secreted primarily from monocytes and fibroblasts. Alterations in IP-10 levels have been associated with inflammatory conditions including viral and bacterial infections, immune dysfunction, and tumor development. IP-10 is increasingly recognized as a b...... as a biomarker that predicts severity of various diseases and can be used in the immunodiagnostics of Mycobacterium tuberculosis and cytomegalovirus infection. Here, we describe an ELISA-based method to detect IP-10 from dried blood and plasma spot samples....

  7. Pressure ulcer incidence and progression in critically ill subjects: influence of low air loss mattress versus a powered air pressure redistribution mattress.

    Science.gov (United States)

    Black, Joyce; Berke, Christine; Urzendowski, Gail

    2012-01-01

    The primary objective of this study was to compare facility-acquired pressure ulcer incidence and progression of pressure ulcers present on admission in critically ill patients, using 2 different support surfaces. We completed a comparison cohort study in a surgical intensive care unit (ICU). The study setting was a 12-bed cardiovascular ICU in a university-based hospital in the Midwestern United States. The sample comprised 52 critically ill patients; 31 were placed on low air loss weight-based pressure redistribution-microclimate management system beds and 21 were placed on integrated powered air pressure redistribution beds. Prior to the start of the study, 5 low airloss beds were placed in open rooms in the cardiovascular surgical ICU. Inclusion criteria were anticipated ICU stay of 3 days, and patients did not receive a speciality bed for pulmonary or wound issues. Initial assessment of the patients included risk assessment and prior events that would increase risk for pressure ulcer development such as extended time in operating room, along with skin assessment for existing pressure ulcers. Subjects in both groups had ongoing skin assessment every 3 to 4 days and a subjective evaluation of heel elevation and turning or repositioning by the researcher. Data were collected until the subjects were dismissed from the ICU. Patients admitted to the unit were assigned to open rooms following the usual protocols. The mean length of stay was 7.0 days, with an 8.1-day length of stay for subjects on "low air loss with microclimate management" beds (LAL-MCM) and 6.6 days on the integrated power pressure air redistribution (IP-AR) beds (P = NS). The incidence of pressure ulcers on the buttocks, sacrum, or coccyx was 0% (0/31) on the low air loss bed and 18% (4/21) on the IP-AR bed (P = .046). Five subjects had 6 pressure ulcers on admission. Two pressure ulcers on 2 patients worsened on the integrated power air redistribution beds, which required specialty bed rental

  8. CATCHprofiles: Clustering and Alignment Tool for ChIP Profiles

    DEFF Research Database (Denmark)

    G. G. Nielsen, Fiona; Galschiøt Markus, Kasper; Møllegaard Friborg, Rune

    2012-01-01

    IP-profiling data and detect potentially meaningful patterns, the areas of enrichment must be aligned and clustered, which is an algorithmically and computationally challenging task. We have developed CATCHprofiles, a novel tool for exhaustive pattern detection in ChIP profiling data. CATCHprofiles is built upon...... a computationally efficient implementation for the exhaustive alignment and hierarchical clustering of ChIP profiling data. The tool features a graphical interface for examination and browsing of the clustering results. CATCHprofiles requires no prior knowledge about functional sites, detects known binding patterns...... it an invaluable tool for explorative research based on ChIP profiling data. CATCHprofiles and the CATCH algorithm run on all platforms and is available for free through the CATCH website: http://catch.cmbi.ru.nl/. User support is available by subscribing to the mailing list catch-users@bioinformatics.org....

  9. Numerical study of IP3-induced Ca2+ spiral pattern evolution

    International Nuclear Information System (INIS)

    Tang Jun; Ma Jun; Yi Ming; Jia Ya

    2008-01-01

    The effect of change in concentration of messenger molecule inositol 1,4,5-trisphosphate (IP 3 ) on intracellular Ca 2+ spiral pattern evolution is studied numerically. The results indicate that when the IP 3 concentration decreases from 0.27 μM, a physiologically reasonable value, to different values, the spiral centre drifts to the edge of the medium and disappears for a small enough IP 3 concentration. The instability of spiral pattern can be understood in terms of excitability-change controlled by the IP 3 concentration. On the other hand, when the IP 3 concentration increases from 0.27 μM, a homogeneous area with a high Ca 2+ concentration emerges and competes with the spiral pattern. A high enough IP 3 concentration can lead the homogeneous area to occupy the whole medium. The instability of spiral pattern is ascribed to the change in stability of a stationary state with a high Ca 2+ concentration. (general)

  10. Application of Mobile-ip to Space and Aeronautical Networks

    Science.gov (United States)

    Leung, Kent; Shell, Dan; Ivancic, William D.; Stewart, David H.; Bell, Terry L.; Kachmar, Brian A.

    2001-01-01

    The National Aeronautics and Space Administration (NASA) is interested in applying mobile Internet protocol (mobile-ip) technologies to its space and aeronautics programs. In particular, mobile-ip will play a major role in the Advanced Aeronautic Transportation Technology (AAT-F), the Weather Information Communication (WINCOMM), and the Small Aircraft Transportation System (SATS) aeronautics programs. This paper describes mobile-ip and mobile routers--in particular, the features, capabilities, and initial performance of the mobile router are presented. The application of mobile-router technology to NASA's space and aeronautics programs is also discussed.

  11. Power quality and integration of wind farms in weak grids in India

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, P.; Hauge Madsen, P. [Risoe National Lab., Roskilde (Denmark). Wind Energy and Atmospheric Physics Dept.; Vikkelsoe, A.; Koelbaek Jensen, K. [Danske Elvaerkers Forening Udredningsafdelingen (DEFU), Lyngby (Denmark); Fathima, K.A.; Unnikrishnan, A.K.

    2000-04-01

    This is the final report of a joint Danish and Indian project' Power Quality and Integration of Wind Farms in Weak Grids'. The power quality issues have been studied and analysed with the Indian conditions as a case. On the basis of meetings with Danish wind turbine industry, Indian electricity boards, nodal agencies, wind turbine industry and authorities, the critical power quality as-pects in India have been identified. Measurements on selected wind farms and wind turbines have quantified the power quality, and analyses of power quality issues, especially reactive power compensation, have been performed. Based on measurements and analyses, preliminary recommendations for grid integration of wind turbines in weak grids have been formulated. (au)

  12. Why (and how) to regulate power exchanges in the EU market integration context?

    International Nuclear Information System (INIS)

    Meeus, Leonardo

    2011-01-01

    The European Union (EU) market integration is leading to increasingly monopolistic electricity market infrastructures, which has opened a debate on the regulation of these so-called power exchanges. In this paper, we start by stating that there are two types of power exchanges in Europe, i.e. 'merchant' and 'cost-of-service regulated' power exchanges. We then discuss how regulation can be used to better align their incentives with the main power exchange tasks. We conclude that adopting the cost-of-service regulated model for all power exchanges in Europe could be counterproductive in the current context, but that regulation can help ensure that the benefits of the EU market integration materialize. Promising regulatory actions include tempering the reinforced market power of power exchanges, and quality-of-service regulation for the ongoing cooperation among power exchanges to organize trade across borders. - Research highlights: → Market integration is leading to increasingly monopolistic electricity market infrastructures. → Regulation can help tempering the market power of these so-called power exchanges in Europe. → Cost-of-service regulation for all power exchanges could however be counterproductive. → More promising is to subject cooperation among power exchanges to quality of service regulation.

  13. Non-exclusive satellite power system

    Energy Technology Data Exchange (ETDEWEB)

    Drummond, J.E. (Power Conversion Technology, Inc., San Diego, Calif.); Cowhey, P.F. (California, University, La Jolla, Calif.)

    1980-09-01

    A modification of the satellite solar power system employing smaller satellites that are not stationary but move in circular or elliptical orbits of two or three hour periods is discussed. The orbits could be inclined at plus or minus 63.4 deg, 73.1 deg, or 14.3 deg to the equatorial plane. This Interregional or Isoinsolation Power System (IPS) greatly reduces the mass and cost of the antenna needed in the sky and the area required for the rectenna and safety region on the ground (the product of the areas of the antennas and rectennas of the IPS system being between 10 and 20 times lower than that required in the conventional SPS system). International control of IPS through a Solar Satellite Consortium (Solsat) is advocated, patterned after the successful Intelsat consortium, and it is stressed that the system must not be allowed to acquire a military capacity. It is emphasized that the smaller rectennas would not destabilize the ionosphere.

  14. Mathematical Representation of VoIP Connection Delay

    Directory of Open Access Journals (Sweden)

    M. Halas

    2007-09-01

    Full Text Available The main topic of this article is to define mathematical formulation of VoIP connection delay model. It handles about all partial delay components, the mechanism of their generation, facilities and their mathematical formulation. Thereafter based on mathematical formulation of all partial delay components, the final mathematical model of whole VoIP call delay is created. In conclusion of this article the results of the designed mathematical model are compared with the experimentally gained results.

  15. The Regulatory Challenges and Opportunities of IP Telephony: Perspective on Malaysia

    OpenAIRE

    Md Khaled Shukran

    2011-01-01

    IP telephony is a transmission of voice and data over Packet Switched IP Networks and it has become a key issue in the telecommunication industry worldwide because of its higher efficiency and cheapest call rate. Hence, most of the countries in the world set up their telecommunication platform on IP based network as a fast revenue generating sources. Though Malaysia is on the way forward on IP based platform but the growth is not reached at satisfactory level due to the absence of effective r...

  16. Evaluation and Investigation of the Delay in VoIP Networks

    Directory of Open Access Journals (Sweden)

    V. Janata

    2011-06-01

    Full Text Available The paper is focused mainly on the delay problems, which considerably influence the final quality of connections in VoIP (Voice over IP networks. The paper provides a detailed exploration of the nature and mechanisms of the delay. The main purpose of the investigation was an attempt to formulate a mathematical model of delay in the VoIP network and its subsequent analysis by laboratory data.

  17. Research and Application of Construction of Operation Integration for Smart Power Distribution and Consumption Based on “Integration of Marketing with Distribution”

    Directory of Open Access Journals (Sweden)

    Zhenbao Feng

    2014-05-01

    Full Text Available The “information integrated platform of marketing and distribution integration system” researched and developed by this article is an advanced application platform to concurrently design and develop the automation of marketing and power distribution through integration and analysis of existing data based on the data platform of Jiaozuo Power Supply Corporation. It uses data mining and data bus technology, uniform analysis of comprehensive marketing and distribution data. And it conducts a real time monitoring on power utilization information for marketing and early warning maintenance business of power distribution according to electric business model, which realizes an integration of marketing and distribution business, achieves the target of integrated operation of marketing and distribution, improves the operation level of business, reduces maintenance costs of distribution grid, increases electricity sales of distribution grid and provide reliable practical basis for operation and maintenance of Jiaozuo power marketing and distribution.

  18. Digital signage sobre IP

    OpenAIRE

    Casademont Filella, Albert

    2012-01-01

    Projecte que versa sobre el disseny i la implementació d'un sistema de Digital Signage (Cartelleria Digital) sobre IP, creant un gestor que permeti controlar de forma remota tot un conjunt de petits dispositius connectats a pantalles que emeten continguts multimèdia com vídeos, imatges, feeds rss...

  19. Ultra low-power integrated circuit design for wireless neural interfaces

    CERN Document Server

    Holleman, Jeremy; Otis, Brian

    2014-01-01

    Presenting results from real prototype systems, this volume provides an overview of ultra low-power integrated circuits and systems for neural signal processing and wireless communication. Topics include analog, radio, and signal processing theory and design for ultra low-power circuits.

  20. Standardization efforts in IP telephony

    Science.gov (United States)

    Sengodan, Senthil; Bansal, Raj

    1999-11-01

    The recent interest in IP telephony has led to a tremendous increase of standardization activities in the area. The three main standards bodies in the area of IP telephony are the International Telecommunication Union's (ITU-T) Study Group (SG) 16, the Internet Engineering Task Force (IETF) and the European Telecommunication Standards Institute's (ETSI) TIPHON project. In addition, forums such as the International Multimedia Teleconferencing Consortium (IMTC), the Intelligent Network Forum (INF), the International Softswitch Consortium (ISC), the Electronic Computer Telephony Forum (ECTF), and the MIT's Internet Telephony Consortium (ITC) are looking into various other aspects that aim at the growth of this industry. This paper describes the main tasks (completed and in progress) undertaken by these organizations. In describing such work, an overview of the underlying technology is also provided.

  1. Extraction Of Electronic Evidence From VoIP: Identification & Analysis Of Digital Speech

    Directory of Open Access Journals (Sweden)

    David Irwin

    2012-09-01

    Full Text Available The Voice over Internet Protocol (VoIP is increasing in popularity as a cost effective and efficient means of making telephone calls via the Internet. However, VoIP may also be an attractive method of communication to criminals as their true identity may be hidden and voice and video communications are encrypted as they are deployed across the Internet. This produces in a new set of challenges for forensic analysts compared with traditional wire-tapping of the Public Switched Telephone Network (PSTN infrastructure, which is not applicable to VoIP. Therefore, other methods of recovering electronic evidence from VoIP are required.  This research investigates the analysis and recovery of digitised human, which persists in computer memory after a VoIP call.This paper proposes a proof of concept how remnants of digitised human speech from a VoIP call may be identified within a forensic memory capture based on how the human voice is detected via a microphone and encoded to a digital format using the sound card of your personal computer. This digital format is unencrypted whist processed in Random Access Memory (RAM before it is passed to the VoIP application for encryption and  transmission over the Internet. Similarly, an incoming encrypted VoIP call is decrypted by the VoIP application and passes through RAM unencrypted in order to be played via the speaker output.A series of controlled tests were undertaken whereby RAM captures were analysed for remnants of digital speech after a VoIP audio call with known conversation. The identification and analysis of digital speech from RAM attempts to construct an automatic process for the identification and subsequent reconstruction of the audio content of a VoIP call.

  2. A Reactive and Cycle-True IP Emulator for MPSoC Exploration

    DEFF Research Database (Denmark)

    Mahadevan, Shankar; Angiolini, Federico; Sparsø, Jens

    2008-01-01

    The design of MultiProcessor Systems-on-Chip (MPSoC) emphasizes intellectual-property (IP)-based communication-centric approaches. Therefore, for the optimization of the MPSoC interconnect, the designer must develop traffic models that realistically capture the application behavior as executing...... on the IP core. In this paper, we introduce a Reactive IP Emulator (RIPE) that enables an effective emulation of the IP-core behavior in multiple environments, including bit and cycle-true simulation. The RIPE is built as a multithreaded abstract instruction-set processor, and it can generate reactive...

  3. Low-power analog integrated circuits for wireless ECG acquisition systems.

    Science.gov (United States)

    Tsai, Tsung-Heng; Hong, Jia-Hua; Wang, Liang-Hung; Lee, Shuenn-Yuh

    2012-09-01

    This paper presents low-power analog ICs for wireless ECG acquisition systems. Considering the power-efficient communication in the body sensor network, the required low-power analog ICs are developed for a healthcare system through miniaturization and system integration. To acquire the ECG signal, a low-power analog front-end system, including an ECG signal acquisition board, an on-chip low-pass filter, and an on-chip successive-approximation analog-to-digital converter for portable ECG detection devices is presented. A quadrature CMOS voltage-controlled oscillator and a 2.4 GHz direct-conversion transmitter with a power amplifier and upconversion mixer are also developed to transmit the ECG signal through wireless communication. In the receiver, a 2.4 GHz fully integrated CMOS RF front end with a low-noise amplifier, differential power splitter, and quadrature mixer based on current-reused folded architecture is proposed. The circuits have been implemented to meet the specifications of the IEEE 802.15.4 2.4 GHz standard. The low-power ICs of the wireless ECG acquisition systems have been fabricated using a 0.18 μm Taiwan Semiconductor Manufacturing Company (TSMC) CMOS standard process. The measured results on the human body reveal that ECG signals can be acquired effectively by the proposed low-power analog front-end ICs.

  4. Integrative ChIP-seq/microarray analysis identifies a CTNNB1 target signature enriched in intestinal stem cells and colon cancer.

    Science.gov (United States)

    Watanabe, Kazuhide; Biesinger, Jacob; Salmans, Michael L; Roberts, Brian S; Arthur, William T; Cleary, Michele; Andersen, Bogi; Xie, Xiaohui; Dai, Xing

    2014-01-01

    Deregulation of canonical Wnt/CTNNB1 (beta-catenin) pathway is one of the earliest events in the pathogenesis of colon cancer. Mutations in APC or CTNNB1 are highly frequent in colon cancer and cause aberrant stabilization of CTNNB1, which activates the transcription of Wnt target genes by binding to chromatin via the TCF/LEF transcription factors. Here we report an integrative analysis of genome-wide chromatin occupancy of CTNNB1 by chromatin immunoprecipitation coupled with high-throughput sequencing (ChIP-seq) and gene expression profiling by microarray analysis upon RNAi-mediated knockdown of CTNNB1 in colon cancer cells. We observed 3629 CTNNB1 binding peaks across the genome and a significant correlation between CTNNB1 binding and knockdown-induced gene expression change. Our integrative analysis led to the discovery of a direct Wnt target signature composed of 162 genes. Gene ontology analysis of this signature revealed a significant enrichment of Wnt pathway genes, suggesting multiple feedback regulations of the pathway. We provide evidence that this gene signature partially overlaps with the Lgr5+ intestinal stem cell signature, and is significantly enriched in normal intestinal stem cells as well as in clinical colorectal cancer samples. Interestingly, while the expression of the CTNNB1 target gene set does not correlate with survival, elevated expression of negative feedback regulators within the signature predicts better prognosis. Our data provide a genome-wide view of chromatin occupancy and gene regulation of Wnt/CTNNB1 signaling in colon cancer cells.

  5. Chip-integrated optical power limiter based on an all-passive micro-ring resonator

    Science.gov (United States)

    Yan, Siqi; Dong, Jianji; Zheng, Aoling; Zhang, Xinliang

    2014-10-01

    Recent progress in silicon nanophotonics has dramatically advanced the possible realization of large-scale on-chip optical interconnects integration. Adopting photons as information carriers can break the performance bottleneck of electronic integrated circuit such as serious thermal losses and poor process rates. However, in integrated photonics circuits, few reported work can impose an upper limit of optical power therefore prevent the optical device from harm caused by high power. In this study, we experimentally demonstrate a feasible integrated scheme based on a single all-passive micro-ring resonator to realize the optical power limitation which has a similar function of current limiting circuit in electronics. Besides, we analyze the performance of optical power limiter at various signal bit rates. The results show that the proposed device can limit the signal power effectively at a bit rate up to 20 Gbit/s without deteriorating the signal. Meanwhile, this ultra-compact silicon device can be completely compatible with the electronic technology (typically complementary metal-oxide semiconductor technology), which may pave the way of very large scale integrated photonic circuits for all-optical information processors and artificial intelligence systems.

  6. Integration of Wind Power into the Danish Power System

    DEFF Research Database (Denmark)

    Rácz, Viktor J.; Yadav, Priyadarshini; Vestergaard, Niels

    Wind energy is a major player in the Danish electricity market with an ambitious goal to pursue 50% of the electricity market by 2020. This paper examines the economic impacts of increasing integration of large-scale wind power to the existing electrical grid. Firstly, we survey the literature...... the price of electricity. We have observed the degree of influence of the fossil fuel prices, total demand, wind power production and import on the electricity price and the individual co-efficiency for the years 2000, 2005 and 2010, according to the energy mix. Using a grid management model for the Western...... Denmark region, we simulate the effect of an increase in wind penetration level on the electricity generation costs and on the CO2 emissions at various penetration levels. The results show that as the wind penetration level increases the cost of electricity production rises thus, reducing the CO2 emission...

  7. Integrated Computing, Communication, and Distributed Control of Deregulated Electric Power Systems

    Energy Technology Data Exchange (ETDEWEB)

    Bajura, Richard; Feliachi, Ali

    2008-09-24

    Restructuring of the electricity market has affected all aspects of the power industry from generation to transmission, distribution, and consumption. Transmission circuits, in particular, are stressed often exceeding their stability limits because of the difficulty in building new transmission lines due to environmental concerns and financial risk. Deregulation has resulted in the need for tighter control strategies to maintain reliability even in the event of considerable structural changes, such as loss of a large generating unit or a transmission line, and changes in loading conditions due to the continuously varying power consumption. Our research efforts under the DOE EPSCoR Grant focused on Integrated Computing, Communication and Distributed Control of Deregulated Electric Power Systems. This research is applicable to operating and controlling modern electric energy systems. The controls developed by APERC provide for a more efficient, economical, reliable, and secure operation of these systems. Under this program, we developed distributed control algorithms suitable for large-scale geographically dispersed power systems and also economic tools to evaluate their effectiveness and impact on power markets. Progress was made in the development of distributed intelligent control agents for reliable and automated operation of integrated electric power systems. The methodologies employed combine information technology, control and communication, agent technology, and power systems engineering in the development of intelligent control agents for reliable and automated operation of integrated electric power systems. In the event of scheduled load changes or unforeseen disturbances, the power system is expected to minimize the effects and costs of disturbances and to maintain critical infrastructure operational.

  8. The international power market: Myth and reality

    International Nuclear Information System (INIS)

    Bailly, H.C.; Roseman, E.

    1992-01-01

    As the market for independent power (IP) explodes overseas, a number of companies that have been active in project development in the United States are looking hungrily abroad. Some developers view the international market as less competitive than in the U.S., and many are attracted by its size. The backlog of IP activity overseas has now reached over 140,000 MW, primarily in Asia and Europe. The U.S. has about a ten-year head start on IP projects abroad, where project activity has taken off only in the last three years. In 1978, the Public Utility Regulatory Policies Acr (PURPA) required U.S. utilities to purchase power from developers of qualified facilities (QFs), and in the process, created a business that has thrown to over $10 billion in annual sales. Since 1985, IP has added as much new capacity as utilities. The authors project that in the 1990s, IP will add 45-50 GW of new capacity, or between 40%-50% of total U.S. capacity. With nearly 3,200 IP projects (over 46,000 MW) on line in the U.S., many developers are hoping that their U.S. experience will serve them well in developing projects elsewhere. Moreover, many developers expect that such experience will give them a leg up on foreign competitors, who have few, if any, megawatts on line. Do these hopes reflect the emerging reality, or are they dangerous misinformation? As U.S. developers approach projects elsewhere, what are the key advantages and constraints their U.S. experience confers? This paper reviews five common myths about the international market for IP and compares the U.S. market with the opportunities abroad. In the process, the authors explore issues specific to IP, not general issues of doing business outside the U.S

  9. VoIP under the EU regulatory framework : preventing foreclosure?

    NARCIS (Netherlands)

    Sadowski, B.M.; Straathof, B.

    2005-01-01

    In June 2004, the European Commission (EC) issued an "Information and Consultation Document" (European Commission 2004) that discussed how the Regulatory Framework of the European Union (EU) should be adapted to accommodate Voice over IP (VoIP) and invited relevant parties to comment on the

  10. Non-integrability of the Anisotropic Stormer Problem and the Isosceles Three-Body Problem

    Science.gov (United States)

    Nomikos, D. G.; Papageorgiou, V. G.

    2009-02-01

    We study the Anisotropic Stormer Problem (ASP) and the Isosceles Three-Body Problem (IP), from the viewpoint of integrability, using Morales-Ramis theory and its generalization. The study of their integrability presents particular interest since they model important physical phenomena. Both problems can be reduced with respect to the S1 symmetry. Almeida and Stuchi [M.A. Almeida, T.J. Stuchi, Non-integrability of the anisotropic Stormer problem with angular momentum, Physica D 189 (2004) 219-233] proved that the reduced ASP is non-integrable for almost all values of the parameters. In this paper we establish the non-integrability (in the extended Liouville sense) of the remaining cases. The IP is a special case of the three-body problem and it can be considered as a generalization of the Sitnikov problem. Here we prove that the complexified reduced IP does not admit an additional independent meromorphic first integral.

  11. On the Cryptographic Features of a VoIP Service

    Directory of Open Access Journals (Sweden)

    Dimitrios Alvanos

    2018-01-01

    Full Text Available Security issues of typical Voice over Internet Protocol (VoIP applications are studied in this paper; in particular, the open source Linphone application is being used as a case study. An experimental analysis indicates that protecting signalling data with the TLS protocol, which unfortunately is not always the default option, is needed to alleviate several security concerns. Moreover, towards improving security, it is shown that a VoIP application may operate over a virtual private network without significantly degrading the overall performance. The conclusions of this study provide useful insights to the usage of any VoIP application.

  12. Integration of Photovoltaic Plants and Supercapacitors in Tramway Power Systems

    Directory of Open Access Journals (Sweden)

    Flavio Ciccarelli

    2018-02-01

    Full Text Available The growing interest in the use of energy storage systems to improve the performance of tramways has prompted the development of control techniques and optimal storage devices, displacement, and sizing to obtain the maximum profit and reduce the total installation cost. Recently, the rapid diffusion of renewable energy generation from photovoltaic panels has also created a large interest in coupling renewable energy and storage units. This study analyzed the integration of a photovoltaic power plant, supercapacitor energy storage system, and railway power system. Random optimization was used to verify the feasibility of this integration in a real tramway electric system operating in the city of Naples, and the benefits and total cost of this integration were evaluated.

  13. Dynamic model of frequency control in Danish power system with large scale integration of wind power

    DEFF Research Database (Denmark)

    Basit, Abdul; Hansen, Anca Daniela; Sørensen, Poul Ejnar

    2013-01-01

    This work evaluates the impact of large scale integration of wind power in future power systems when 50% of load demand can be met from wind power. The focus is on active power balance control, where the main source of power imbalance is an inaccurate wind speed forecast. In this study, a Danish...... power system model with large scale of wind power is developed and a case study for an inaccurate wind power forecast is investigated. The goal of this work is to develop an adequate power system model that depicts relevant dynamic features of the power plants and compensates for load generation...... imbalances, caused by inaccurate wind speed forecast, by an appropriate control of the active power production from power plants....

  14. Management information system for cost-schedule integration control for nuclear power projects

    International Nuclear Information System (INIS)

    Liu Wei; Wang Yongqing; Tian Li

    2001-01-01

    Based on the project management experience abroad and at home, a cost-schedule integration control model was developed to improve nuclear power project management. The model integrates cost data with the scheduling data by unity coding to efficiently implement cost-schedule integration control on line. The software system architecture and database is designed and implemented. The system functions include estimating and forecasting dynamically cash flow, scheduling and evaluating deviation from the cost-schedule plan, etc. The research and development of the system should improve the architecture of computer integrated management information systems for nuclear power projects in China

  15. Challenges and options for large scale integration of wind power

    International Nuclear Information System (INIS)

    Tande, John Olav Giaever

    2006-01-01

    Challenges and options for large scale integration of wind power are examined. Immediate challenges are related to weak grids. Assessment of system stability requires numerical simulation. Models are being developed - validation is essential. Coordination of wind and hydro generation is a key for allowing more wind power capacity in areas with limited transmission corridors. For the case study grid depending on technology and control the allowed wind farm size is increased from 50 to 200 MW. The real life example from 8 January 2005 demonstrates that existing marked based mechanisms can handle large amounts of wind power. In wind integration studies it is essential to take account of the controllability of modern wind farms, the power system flexibility and the smoothing effect of geographically dispersed wind farms. Modern wind farms contribute to system adequacy - combining wind and hydro constitutes a win-win system (ml)

  16. Evaluation of wind power planning in Denmark – Towards an integrated perspective

    DEFF Research Database (Denmark)

    Sperling, Karl; Hvelplund, Frede; Mathiesen, Brian Vad

    2010-01-01

    Wind power is a maturing technology that may form an essential element of fully renewable energy systems in a number of countries. Denmark has a long history of wind power development and is planning to expand its existing capacity. If large-scale penetration of wind power is to be achieved......, an integrated framework is needed that can respond to the associated challenges. This paper argues for adopting an integrated macro perspective when evaluating and building frameworks to support wind power development. This macro perspective is applied to the case of Denmark, and more specifically to concrete...

  17. Unveiling combinatorial regulation through the combination of ChIP information and in silico cis-regulatory module detection

    Science.gov (United States)

    Sun, Hong; Guns, Tias; Fierro, Ana Carolina; Thorrez, Lieven; Nijssen, Siegfried; Marchal, Kathleen

    2012-01-01

    Computationally retrieving biologically relevant cis-regulatory modules (CRMs) is not straightforward. Because of the large number of candidates and the imperfection of the screening methods, many spurious CRMs are detected that are as high scoring as the biologically true ones. Using ChIP-information allows not only to reduce the regions in which the binding sites of the assayed transcription factor (TF) should be located, but also allows restricting the valid CRMs to those that contain the assayed TF (here referred to as applying CRM detection in a query-based mode). In this study, we show that exploiting ChIP-information in a query-based way makes in silico CRM detection a much more feasible endeavor. To be able to handle the large datasets, the query-based setting and other specificities proper to CRM detection on ChIP-Seq based data, we developed a novel powerful CRM detection method ‘CPModule’. By applying it on a well-studied ChIP-Seq data set involved in self-renewal of mouse embryonic stem cells, we demonstrate how our tool can recover combinatorial regulation of five known TFs that are key in the self-renewal of mouse embryonic stem cells. Additionally, we make a number of new predictions on combinatorial regulation of these five key TFs with other TFs documented in TRANSFAC. PMID:22422841

  18. Method for assessing wind power integration in a hydro based power system

    International Nuclear Information System (INIS)

    Norheim, I.; Palsson, M.; Tande, J.O.G.; Uhlen, K.

    2006-01-01

    The present paper demonstrates a method for assessment of how much wind power that can be integrated in a system with limited transmission capacity. Based on hydro inflow data and wind measurements (for different locations of planned wind farms in an area) it is possible to assess how much wind power that can be fed into a certain point in the transmission network without violating the transmission capacity limits. The proposed method combines the use of market modelling and detailed network analysis in order to assess the probability of network congestions rather than focusing on extreme cases. By computing the probability distribution of power flow on critical corridors in the grid it is possible to assess the likelihood of network congestions and the amount of energy that must be curtailed to fulfil power system security requirements (n-1). This way the assessment is not only made of worst case scenarios, assuming maximal flow from hydro plants and maximal wind power production. As extreme case scenarios are short term and may be solved by market mechanisms or automatic system protection schemes (disconnection of wind power or hydro power), the proposed method may reveal that it would be economic to install more wind power than if only based on analysis of worst case scenarios. (orig.)

  19. Why (and how) to regulate power exchanges in the EU market integration context?

    Energy Technology Data Exchange (ETDEWEB)

    Meeus, Leonardo, E-mail: leonardo.meeus@eui.e [Florence School of Regulation, Robert Schuman Centre for Advanced Studies, European University Institute, Via Boccaccio 151, Florence (Italy); Electrical Engineering Department (ESAT-ELECTA), KULeuven, Kasteelpark Arenberg 10, Heverlee (Belgium)

    2011-03-15

    The European Union (EU) market integration is leading to increasingly monopolistic electricity market infrastructures, which has opened a debate on the regulation of these so-called power exchanges. In this paper, we start by stating that there are two types of power exchanges in Europe, i.e. 'merchant' and 'cost-of-service regulated' power exchanges. We then discuss how regulation can be used to better align their incentives with the main power exchange tasks. We conclude that adopting the cost-of-service regulated model for all power exchanges in Europe could be counterproductive in the current context, but that regulation can help ensure that the benefits of the EU market integration materialize. Promising regulatory actions include tempering the reinforced market power of power exchanges, and quality-of-service regulation for the ongoing cooperation among power exchanges to organize trade across borders. - Research highlights: {yields} Market integration is leading to increasingly monopolistic electricity market infrastructures. {yields} Regulation can help tempering the market power of these so-called power exchanges in Europe. {yields} Cost-of-service regulation for all power exchanges could however be counterproductive. {yields} More promising is to subject cooperation among power exchanges to quality of service regulation.

  20. IP and resistivity survey at the INEL cold test pit

    International Nuclear Information System (INIS)

    Frangos, W.

    1997-01-01

    Induced polarization (IP) is a technique for detection of diffuse occurrences of metallic material. The Idaho National Laboratory (INEL) Cold Test Pit (CTP) has been carefully constructed to simulate stored hazardous waste occurrences. IP and resistivity surveys of the CTP show a very strong IP response and a modest resistivity response associated with the simulated waste. Several false positive resistivity anomalies are noted. 2-D inversion of the data accurately determine the lateral limits of the waste zone. The depth of burial indicated is deeper than reported by the construction engineers. Limited depth extent is recognized, in distinction to results from other, resistivity-based, methods, but it also appears too deep. IP holds promise as a method for locating buried waste

  1. Developments of integrity evaluation technology for pressurized components in nuclear power plant and IT based integrity evaluation system

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Jin; Choi, Jae Boong; Shim, Do Jun [Sungkyunkwan Univ., Seoul (Korea, Republic of)] (and others)

    2003-03-15

    The objective of this research is to develop an efficient evaluation technology and to investigate applicability of newly-developed technology, such as internet-based cyber platform, to operating power plants. Development of efficient evaluation systems for Nuclear Power Plant components, based on structural integrity assessment techniques, are increasingly demanded for safe operation with the increasing operating period of Nuclear Power Plants. The following five topics are covered in this project: development of assessment method for wall-thinned nuclear piping based on pipe test; development of structural integrity program for steam generator tubes with cracks of various shape; development of fatigue life evaluation system for mam components of NPP; development of internet-based cyber platform and integrity program for primary components of NPP; effect of aging on strength of dissimilar welds.

  2. Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data.

    Science.gov (United States)

    Waszak, Sebastian M; Kilpinen, Helena; Gschwind, Andreas R; Orioli, Andrea; Raghav, Sunil K; Witwicki, Robert M; Migliavacca, Eugenia; Yurovsky, Alisa; Lappalainen, Tuuli; Hernandez, Nouria; Reymond, Alexandre; Dermitzakis, Emmanouil T; Deplancke, Bart

    2014-01-15

    High-throughput sequencing technologies enable the genome-wide analysis of the impact of genetic variation on molecular phenotypes at unprecedented resolution. However, although powerful, these technologies can also introduce unexpected artifacts. We investigated the impact of library amplification bias on the identification of allele-specific (AS) molecular events from high-throughput sequencing data derived from chromatin immunoprecipitation assays (ChIP-seq). Putative AS DNA binding activity for RNA polymerase II was determined using ChIP-seq data derived from lymphoblastoid cell lines of two parent-daughter trios. We found that, at high-sequencing depth, many significant AS binding sites suffered from an amplification bias, as evidenced by a larger number of clonal reads representing one of the two alleles. To alleviate this bias, we devised an amplification bias detection strategy, which filters out sites with low read complexity and sites featuring a significant excess of clonal reads. This method will be useful for AS analyses involving ChIP-seq and other functional sequencing assays. The R package abs filter for library clonality simulations and detection of amplification-biased sites is available from http://updepla1srv1.epfl.ch/waszaks/absfilter

  3. A High Power Density Integrated Charger for Electric Vehicles with Active Ripple Compensation

    Directory of Open Access Journals (Sweden)

    Liwen Pan

    2015-01-01

    Full Text Available This paper suggests a high power density on-board integrated charger with active ripple compensation circuit for electric vehicles. To obtain a high power density and high efficiency, silicon carbide devices are reported to meet the requirement of high-switching-frequency operation. An integrated bidirectional converter is proposed to function as AC/DC battery charger and to transfer energy between battery pack and motor drive of the traction system. In addition, the conventional H-bridge circuit suffers from ripple power pulsating at second-order line frequency, and a scheme of active ripple compensation circuit has been explored to solve this second-order ripple problem, in which a pair of power switches shared traction mode, a ripple energy storage capacitor, and an energy transfer inductor. Simulation results in MATLAB/Simulink validated the eligibility of the proposed topology. The integrated charger can work as a 70 kW motor drive circuit or a converter with an active ripple compensation circuit for 3 kW charging the battery. The impact of the proposed topology and control strategy on the integrated charger power losses, efficiency, power density, and thermal performance has also been analysed and simulated.

  4. IP over optical multicasting for large-scale video delivery

    Science.gov (United States)

    Jin, Yaohui; Hu, Weisheng; Sun, Weiqiang; Guo, Wei

    2007-11-01

    In the IPTV systems, multicasting will play a crucial role in the delivery of high-quality video services, which can significantly improve bandwidth efficiency. However, the scalability and the signal quality of current IPTV can barely compete with the existing broadcast digital TV systems since it is difficult to implement large-scale multicasting with end-to-end guaranteed quality of service (QoS) in packet-switched IP network. China 3TNet project aimed to build a high performance broadband trial network to support large-scale concurrent streaming media and interactive multimedia services. The innovative idea of 3TNet is that an automatic switched optical networks (ASON) with the capability of dynamic point-to-multipoint (P2MP) connections replaces the conventional IP multicasting network in the transport core, while the edge remains an IP multicasting network. In this paper, we will introduce the network architecture and discuss challenges in such IP over Optical multicasting for video delivery.

  5. Photometric studies of δ Scuti stars. I. IP Virginis

    Science.gov (United States)

    Joner, Michael D.; Hintz, Eric G.; Collier, Matthew W.

    1998-01-01

    We report 15 new times of maximum light for the δ Scuti star IP Virginis (formerly known as SA 106‐1024). An analysis of all times of maximum light indicates that IP Vir has been decreasing in period at a constant rate of − days day−1. Evidence is also presented that IP Vir is a double‐mode variable with a period ratio of . This period ratio predicts a [Fe/H] value of −0.3. From photometric (uvbyβ) observations, we find a foreground reddening of .008 mag and a metallicity of [Fe/H] = +0.05. It is shown that [Fe/H] = −0.3 is most likely the correct value. Intrinsic ‐ and c1‐values, plotted in a model atmosphere grid, indicate a mean effective temperature, K, and a mean surface gravity, . All of these physical parameters support Landolt's initial conclusion that IP Vir is an ordinary δ Sct star.

  6. Functional-logic simulation of IP-blocks dose functional failures

    Directory of Open Access Journals (Sweden)

    Vyacheslav M. Barbashov

    2017-11-01

    Full Text Available The technique of functional-logical simulation of System-on-Chip (SoC total dose radiation failures is presented based on fuzzy logic sets theory. An analysis of the capabilities of this approach for IP-blocks radiation behavior is carried out along with the analysis of operating modes under irradiation influence on IP-blocks radiation behavior. The following elements of this technique application for simulation of dose radiation failures of various types of IP-units are studied: logical elements, memory units and cells, processors. Examples of criterial membership functions and operability functions construction are given for these IP-units and for various critical parameters characterizing their failures. It is shown that when modeling total dose failures it is necessary to take into account the influence of the functional mode on the model parameters. The technique proposed allows improving the reliability of the SoC radiation hardness estimation, also for the purpose of solving the problems of information security of electronic devices.

  7. An integrated reliability management system for nuclear power plants

    International Nuclear Information System (INIS)

    Kimura, T.; Shimokawa, H.; Matsushima, H.

    1998-01-01

    The responsibility in the nuclear field of the Government, utilities and manufactures has increased in the past years due to the need of stable operation and great reliability of nuclear power plants. The need to improve the reliability is not only for the new plants but also for those now running. So, several measures have been taken to improve reliability. In particular, the plant manufactures have developed a reliability management system for each phase (planning, construction, maintenance and operation) and these have been integrated as a unified system. This integrated reliability management system for nuclear power plants contains information about plant performance, failures and incidents which have occurred in the plants. (author)

  8. CtIP Mutations Cause Seckel and Jawad Syndromes.

    Directory of Open Access Journals (Sweden)

    Per Qvist

    2011-10-01

    Full Text Available Seckel syndrome is a recessively inherited dwarfism disorder characterized by microcephaly and a unique head profile. Genetically, it constitutes a heterogeneous condition, with several loci mapped (SCKL1-5 but only three disease genes identified: the ATR, CENPJ, and CEP152 genes that control cellular responses to DNA damage. We previously mapped a Seckel syndrome locus to chromosome 18p11.31-q11.2 (SCKL2. Here, we report two mutations in the CtIP (RBBP8 gene within this locus that result in expression of C-terminally truncated forms of CtIP. We propose that these mutations are the molecular cause of the disease observed in the previously described SCKL2 family and in an additional unrelated family diagnosed with a similar form of congenital microcephaly termed Jawad syndrome. While an exonic frameshift mutation was found in the Jawad family, the SCKL2 family carries a splicing mutation that yields a dominant-negative form of CtIP. Further characterization of cell lines derived from the SCKL2 family revealed defective DNA damage induced formation of single-stranded DNA, a critical co-factor for ATR activation. Accordingly, SCKL2 cells present a lowered apoptopic threshold and hypersensitivity to DNA damage. Notably, over-expression of a comparable truncated CtIP variant in non-Seckel cells recapitulates SCKL2 cellular phenotypes in a dose-dependent manner. This work thus identifies CtIP as a disease gene for Seckel and Jawad syndromes and defines a new type of genetic disease mechanism in which a dominant negative mutation yields a recessively inherited disorder.

  9. Internet Protocol-Hybrid Opto-Electronic Ring Network (IP-HORNET): A Novel Internet Protocol-Over-Wavelength Division Multiplexing (IP-Over-WDM) Multiple-Access Metropolitan Area Network (MAN)

    Science.gov (United States)

    2003-04-01

    IP-HORNET, Metropolitan Optical Networks 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT UNCLASSIFIED 18. SECURITY CLASSIFICATION...OF THIS PAGE UNCLASSIFIED 19. SECURITY CLASSIFICATION OF ABSTRACT UNCLASSIFIED 20. LIMITATION OF ABSTRACT UL NSN 7540-01-280-5500...Gemelos, and L. G. Kazovsky, “CSMA/CA MAC protocols for IP-HORNET: An IP over WDM metropolitan area ring netowrk ,” in Proceedings of GLOBE- COM’00

  10. Enabling IP Header Compression in COTS Routers via Frame Relay on a Simplex Link

    Science.gov (United States)

    Nguyen, Sam P.; Pang, Jackson; Clare, Loren P.; Cheng, Michael K.

    2010-01-01

    NASA is moving toward a networkcentric communications architecture and, in particular, is building toward use of Internet Protocol (IP) in space. The use of IP is motivated by its ubiquitous application in many communications networks and in available commercial off-the-shelf (COTS) technology. The Constellation Program intends to fit two or more voice (over IP) channels on both the forward link to, and the return link from, the Orion Crew Exploration Vehicle (CEV) during all mission phases. Efficient bandwidth utilization of the links is key for voice applications. In Voice over IP (VoIP), the IP packets are limited to small sizes to keep voice latency at a minimum. The common voice codec used in VoIP is G.729. This new algorithm produces voice audio at 8 kbps and in packets of 10-milliseconds duration. Constellation has designed the VoIP communications stack to use the combination of IP/UDP/RTP protocols where IP carries a 20-byte header, UDP (User Datagram Protocol) carries an 8-byte header, and RTP (Real Time Transport Protocol) carries a 12-byte header. The protocol headers total 40 bytes and are equal in length to a 40-byte G.729 payload, doubling the VoIP latency. Since much of the IP/UDP/RTP header information does not change from IP packet to IP packet, IP/UDP/RTP header compression can avoid transmission of much redundant data as well as reduce VoIP latency. The benefits of IP header compression are more pronounced at low data rate links such as the forward and return links during CEV launch. IP/UDP/RTP header compression codecs are well supported by many COTS routers. A common interface to the COTS routers is through frame relay. However, enabling IP header compression over frame relay, according to industry standard (Frame Relay IP Header Compression Agreement FRF.20), requires a duplex link and negotiations between the compressor router and the decompressor router. In Constellation, each forward to and return link from the CEV in space is treated

  11. Efficient IP Traffic over Optical Network Based on Wavelength Translation Switching

    DEFF Research Database (Denmark)

    Jha, Vikas; Kalia, Kartik; Chowdhary, Bhawani Shankar

    2016-01-01

    With the advent of TCP/IP protocol suite the overall era of communication technologies had been redefined. Now, we can’t ignore the presence of huge amount of IP traffic; data, voice or video increasing day by day creating more pressure on existing communicating media and supporting back bone....... With the humongous popularity of Internet the overall traffic on Internet has the same story. Focusing on transmission of IP traffic in an optical network with signals remaining in their optical nature generated at particular wavelength, proposed is the switching of optically generated IP packets through optical...... cross connects based on translation of wavelength when an IP packet is crossing the optical cross connect. Adding the concepts of layer 3 routing protocols along with the wavelength translation scheme, will help in spanning the overall optical network for a larger area....

  12. Integrated analysis of wind turbines - The impact of power systems on wind turbine design

    DEFF Research Database (Denmark)

    Barahona Garzón, Braulio

    Megawatt-size wind turbines nowadays operate in very complex environmental conditions, and increasingly demanding power system requirements. Pursuing a cost-effective and reliable wind turbine design is a multidisciplinary task. However nowadays, wind turbine design and research areas...... conditions that stem from disturbances in the power system. An integrated simulation environment, wind turbine models, and power system models are developed in order to take an integral perspective that considers the most important aeroelastic, structural, electrical, and control dynamics. Applications...... of the integrated simulation environment are presented. The analysis of an asynchronous machine, and numerical simulations of a fixedspeed wind turbine in the integrated simulation environment, demonstrate the effects on structural loads of including the generator rotor fluxes dynamics in aeroelastic studies. Power...

  13. Capturing value from IP in a global environment

    DEFF Research Database (Denmark)

    Alcacer, Juan; Beukel, Karin; Cassiman, Bruno

    Executive Summary The authors argue that challenges to capturing value from know-how and reputation through the use of different IP tools will be an increasingly important matter of strategy for global enterprises. This has important implications for management practice. Global enterprises...... will need to combine different institutional, market and non-market mechanisms. The precise combination of tools will depend on the local and regional institutional and market conditions. Abstract: This paper documents the strong growth in tools used by firms to protect their intellectual property (IP......), develop their know-how, and build and maintain their reputation globally during the last decades. We focus on three tools: patents, trademarks, and industrial designs. We find that, although most IP applications come from a few countries (the United States, European Union, Japan, China, and South Korea...

  14. An Integrated Design approach to Power Systems: from Power Flows to Electricity Markets

    Science.gov (United States)

    Bose, Subhonmesh

    Power system is at the brink of change. Engineering needs, economic forces and environmental factors are the main drivers of this change. The vision is to build a smart electrical grid and a smarter market mechanism around it to fulfill mandates on clean energy. Looking at engineering and economic issues in isolation is no longer an option today; it needs an integrated design approach. In this thesis, I shall revisit some of the classical questions on the engineering operation of power systems that deals with the nonconvexity of power flow equations. Then I shall explore some issues of the interaction of these power flow equations on the electricity markets to address the fundamental issue of market power in a deregulated market environment. Finally, motivated by the emergence of new storage technologies, I present an interesting result on the investment decision problem of placing storage over a power network. The goal of this study is to demonstrate that modern optimization and game theory can provide unique insights into this complex system. Some of the ideas carry over to applications beyond power systems.

  15. Investments and Operation in an Integrated Power and Transport System

    DEFF Research Database (Denmark)

    Juul, Nina; Boomsma, Trine Krogh

    2013-01-01

    This chapter analyses an integrated power and road transport system. For analysing the influences of including passenger road transport in the energy system, a road transport model is developed. Based on this model, the benefits of integration of the two systems and using electric-drive vehicles ...

  16. Is this the right normalization? A diagnostic tool for ChIP-seq normalization.

    Science.gov (United States)

    Angelini, Claudia; Heller, Ruth; Volkinshtein, Rita; Yekutieli, Daniel

    2015-05-09

    Chip-seq experiments are becoming a standard approach for genome-wide profiling protein-DNA interactions, such as detecting transcription factor binding sites, histone modification marks and RNA Polymerase II occupancy. However, when comparing a ChIP sample versus a control sample, such as Input DNA, normalization procedures have to be applied in order to remove experimental source of biases. Despite the substantial impact that the choice of the normalization method can have on the results of a ChIP-seq data analysis, their assessment is not fully explored in the literature. In particular, there are no diagnostic tools that show whether the applied normalization is indeed appropriate for the data being analyzed. In this work we propose a novel diagnostic tool to examine the appropriateness of the estimated normalization procedure. By plotting the empirical densities of log relative risks in bins of equal read count, along with the estimated normalization constant, after logarithmic transformation, the researcher is able to assess the appropriateness of the estimated normalization constant. We use the diagnostic plot to evaluate the appropriateness of the estimates obtained by CisGenome, NCIS and CCAT on several real data examples. Moreover, we show the impact that the choice of the normalization constant can have on standard tools for peak calling such as MACS or SICER. Finally, we propose a novel procedure for controlling the FDR using sample swapping. This procedure makes use of the estimated normalization constant in order to gain power over the naive choice of constant (used in MACS and SICER), which is the ratio of the total number of reads in the ChIP and Input samples. Linear normalization approaches aim to estimate a scale factor, r, to adjust for different sequencing depths when comparing ChIP versus Input samples. The estimated scaling factor can easily be incorporated in many peak caller algorithms to improve the accuracy of the peak identification. The

  17. Solar Type II Radio Bursts and IP Type II Events

    Science.gov (United States)

    Cane, H. V.; Erickson, W. C.

    2005-01-01

    We have examined radio data from the WAVES experiment on the Wind spacecraft in conjunction with ground-based data in order to investigate the relationship between the shocks responsible for metric type II radio bursts and the shocks in front of coronal mass ejections (CMEs). The bow shocks of fast, large CMEs are strong interplanetary (IP) shocks, and the associated radio emissions often consist of single broad bands starting below approx. 4 MHz; such emissions were previously called IP type II events. In contrast, metric type II bursts are usually narrowbanded and display two harmonically related bands. In addition to displaying complete dynamic spectra for a number of events, we also analyze the 135 WAVES 1 - 14 MHz slow-drift time periods in 2001-2003. We find that most of the periods contain multiple phenomena, which we divide into three groups: metric type II extensions, IP type II events, and blobs and bands. About half of the WAVES listings include probable extensions of metric type II radio bursts, but in more than half of these events, there were also other slow-drift features. In the 3 yr study period, there were 31 IP type II events; these were associated with the very fastest CMEs. The most common form of activity in the WAVES events, blobs and bands in the frequency range between 1 and 8 MHz, fall below an envelope consistent with the early signatures of an IP type II event. However, most of this activity lasts only a few tens of minutes, whereas IP type II events last for many hours. In this study we find many examples in the radio data of two shock-like phenomena with different characteristics that occur simultaneously in the metric and decametric/hectometric bands, and no clear example of a metric type II burst that extends continuously down in frequency to become an IP type II event. The simplest interpretation is that metric type II bursts, unlike IP type II events, are not caused by shocks driven in front of CMEs.

  18. The role of calsenilin/DREAM/KChIP3 in contextual fear conditioning.

    Science.gov (United States)

    Alexander, Jon C; McDermott, Carmel M; Tunur, Tumay; Rands, Vicky; Stelly, Claire; Karhson, Debra; Bowlby, Mark R; An, W Frank; Sweatt, J David; Schrader, Laura A

    2009-03-01

    Potassium channel interacting proteins (KChIPs) are members of a family of calcium binding proteins that interact with Kv4 potassium (K(+)) channel primary subunits and also act as transcription factors. The Kv4 subunit is a primary K(+) channel pore-forming subunit, which contributes to the somatic and dendritic A-type currents throughout the nervous system. These A-type currents play a key role in the regulation of neuronal excitability and dendritic processing of incoming synaptic information. KChIP3 is also known as calsenilin and as the transcription factor, downstream regulatory element antagonist modulator (DREAM), which regulates a number of genes including prodynorphin. KChIP3 and Kv4 primary channel subunits are highly expressed in hippocampus, an area of the brain important for learning and memory. Through its various functions, KChIP3 may play a role in the regulation of synaptic plasticity and learning and memory. We evaluated the role of KChIP3 in a hippocampus-dependent memory task, contextual fear conditioning. Male KChIP3 knockout (KO) mice showed significantly enhanced memory 24 hours after training as measured by percent freezing. In addition, we found that membrane association and interaction with Kv4.2 of KChIP3 protein was significantly decreased and nuclear KChIP3 expression was increased six hours after the fear conditioning training paradigm with no significant change in KChIP3 mRNA. In addition, prodynorphin mRNA expression was significantly decreased six hours after fear conditioning training in wild-type (WT) but not in KO animals. These data suggest a role for regulation of gene expression by KChIP3/DREAM/calsenilin in consolidation of contextual fear conditioning memories.

  19. Consumer motivation towards purchasing fruit from integrated production in Belgium.

    Science.gov (United States)

    Vannoppen, J; Verbeke, W; Van Huylenbroeck, G

    2001-01-01

    Consumer concerns about food safety have been steadily growing during the last decade. Along with the recognition of the increasing power from the consumer side of food chains, this has forced agricultural producers to innovate and adapt their production methods. One of those developments is integrated production of pip fruit (IFP). This research analyses and presents motivational structures of consumers towards purchasing IP fruit in Belgium. The research methodology builds on means-end-chain (MEC) theory, with data collected through personal laddering interviews with consumers. A hierarchical value map, indicating motivational structures for farm shop purchase of IP-labelled apples, is presented. IP-apple buyers pursue typical values, with health being paramount. The findings reveal interactions between market channel characteristics and product attributes, including characteristics that refer to production methods. Also, the study shows how outlet choice influences the perception and the motivation structure of the respondents for the specific product, fresh fruit in this case. From the findings, two sets of implications are set forth. First, marketing implications pertaining to advertising through the application of the "Means-End Conceptualization of the Components of Advertising Strategy" or MECCAS model. Second, implications to producers with respect to adapting their production methods to the needs and wants of the present end consumers.

  20. Research on TCP/IP network communication based on Node.js

    Science.gov (United States)

    Huang, Jing; Cai, Lixiong

    2018-04-01

    In the face of big data, long connection and high synchronization, TCP/IP network communication will cause performance bottlenecks due to its blocking multi-threading service model. This paper presents a method of TCP/IP network communication protocol based on Node.js. On the basis of analyzing the characteristics of Node.js architecture and asynchronous non-blocking I/O model, the principle of its efficiency is discussed, and then compare and analyze the network communication model of TCP/IP protocol to expound the reasons why TCP/IP protocol stack is widely used in network communication. Finally, according to the large data and high concurrency in the large-scale grape growing environment monitoring process, a TCP server design based on Node.js is completed. The results show that the example runs stably and efficiently.

  1. Converter Power Density Increase using Low Inductive Integrated DC-link Capacitor/Bus

    DEFF Research Database (Denmark)

    Trintis, Ionut; Franke, Toke; Rannested, Bjørn

    2015-01-01

    The power losses in switching devices have a direct effect on the maximum converter power. For a voltage source converter, the DC-link bus has a major influence on the power loss and safe operating area of the power devices. The Power Ring Film CapacitorTM integrated with an optimized bus structu...

  2. MICROSOFT DYNAMICS CRM IN CISCO IP TELEFONIJA

    OpenAIRE

    Knez, Margareta

    2011-01-01

    Microsoft Dynamics CRM je le ena od mnogih rešitev CRM, ki se iz dneva v dan bolj izpopolnjuje in postaja prijaznejša za uporabnike. Na trgu je še mnogo drugih konkurenčnih rešitev programskega orodja CRM. Tako je tudi Ciscova IP-telefonija le ena od mnogih ponudnikov te tehnologije. IP-telefonija bo počasi spodrinila navadno telefonsko linijo, saj je veliko cenejša in ponuja še mnogo dodatnih funkcionalnosti. Le lepa beseda in dobra komunikacija sta potrebni, da stranko zadovoljimo in...

  3. Nuclear power programme planning: An integrated approach

    International Nuclear Information System (INIS)

    2001-12-01

    The International Atomic Energy Agency (IAEA) has published material on different policy considerations in the introduction of nuclear power, primarily addressed to top level decision makers in government and industry in Member States. Several Member States and experts recommended to the IAEA to address the aspects of an integrated approach to nuclear power programme planning and to serve as guidance to those countries wishing to embark on a nuclear power programme. As a follow-up, the present publication is primarily intended to serve as guidance for executives and managers in Member States in planning for possible introduction of nuclear power plants in their electricity generating systems. Nuclear power programme planning, as dealt with in this publication, includes all activities that need to be carried out up to a well-founded decision to proceed with a project feasibility study. Project implementation beyond this decision is not in the scope of this publication. Although it is possible to use nuclear energy as a heat source for industrial processes, desalination and other heat applications, it is assumed in this publication that the planning is aimed towards nuclear power for electricity generation. Much of the information given would, however, also be relevant for planning of nuclear reactors for heat production. The publication was prepared within the framework of the IAEA programme on nuclear power planning, implementation and performance as a joint activity of the Nuclear Power Engineering Section and the Planning and Economic Studies Section (Division of Nuclear Power)

  4. A Novel Addressing Scheme for PMIPv6 Based Global IP-WSNs

    Directory of Open Access Journals (Sweden)

    Md. Motaharul Islam

    2011-08-01

    Full Text Available IP based Wireless Sensor Networks (IP-WSNs are being used in healthcare, home automation, industrial control and agricultural monitoring. In most of these applications global addressing of individual IP-WSN nodes and layer-three routing for mobility enabled IP-WSN with special attention to reliability, energy efficiency and end to end delay minimization are a few of the major issues to be addressed. Most of the routing protocols in WSN are based on layer-two approaches. For reliability and end to end communication enhancement the necessity of layer-three routing for IP-WSNs is generating significant attention among the research community, but due to the hurdle of maintaining routing state and other communication overhead, it was not possible to introduce a layer-three routing protocol for IP-WSNs. To address this issue we propose in this paper a global addressing scheme and layer-three based hierarchical routing protocol. The proposed addressing and routing approach focuses on all the above mentioned issues. Simulation results show that the proposed addressing and routing approach significantly enhances the reliability, energy efficiency and end to end delay minimization. We also present architecture, message formats and different routing scenarios in this paper.

  5. A novel addressing scheme for PMIPv6 based global IP-WSNs.

    Science.gov (United States)

    Islam, Md Motaharul; Huh, Eui-Nam

    2011-01-01

    IP based Wireless Sensor Networks (IP-WSNs) are being used in healthcare, home automation, industrial control and agricultural monitoring. In most of these applications global addressing of individual IP-WSN nodes and layer-three routing for mobility enabled IP-WSN with special attention to reliability, energy efficiency and end to end delay minimization are a few of the major issues to be addressed. Most of the routing protocols in WSN are based on layer-two approaches. For reliability and end to end communication enhancement the necessity of layer-three routing for IP-WSNs is generating significant attention among the research community, but due to the hurdle of maintaining routing state and other communication overhead, it was not possible to introduce a layer-three routing protocol for IP-WSNs. To address this issue we propose in this paper a global addressing scheme and layer-three based hierarchical routing protocol. The proposed addressing and routing approach focuses on all the above mentioned issues. Simulation results show that the proposed addressing and routing approach significantly enhances the reliability, energy efficiency and end to end delay minimization. We also present architecture, message formats and different routing scenarios in this paper.

  6. New generation nuclear power units of PWR type integral reactors

    International Nuclear Information System (INIS)

    Mitenkov, F.M.; Kurachen Kov, A.V.; Malamud, V.A.; Panov, Yu.K.; Runov, B.I.; Flerov, L.N.

    1997-01-01

    Design bases of new generation nuclear power units (nuclear power plants - NPP, nuclear co-generation plants - NCP, nuclear distract heating plants - NDHP), using integral type PWPS, developed in OKBM, Nizhny Novgorod and trends of design decisions optimization are considered in this report. The problems of diagnostics, servicing and repair of the integral reactor components in course of operation are discussed. The results of safety analysis, including the problems of several accident localization with postulated core melting and keeping corium in the reactor vessel and guard vessel are presented. Information on experimental substantiation of the suggested plant design decisions is presented. (author)

  7. Review Report on the Design of In-Pile Test Section(IPS)

    International Nuclear Information System (INIS)

    Lee, Jong Min; Park, Kook Nam; Shim, Bong Sik; Lee, Chung Young; Chi, Dae Young; Park, Su Ki; Ahn, Sung Ho; Kim, Young Ki; Lee, Kye Hong; Kim, Kwan Hyun

    2009-01-01

    The In-Pile Test Section(IPS) accommodating fuel pins has loaded IR-1 hole in HANARO has double pressure vessel for the design conditions of 350 deg. C, 17.5 MPa and is composed of outer assembly and inner assembly. Dummy fuel, dummy fuel supports and Top flange are the main components in inner assembly and inner pressure vessel, outer pressure vessel and head are the components in outer assembly. The IPS at current status has dummy fuels and confirm the requirements for the IPS design improvements during the design, manufacturing and installation process. Head, Top Flange, Instrumentation Feed through, Lifting Eye, Fuel Carrier Leg, Retainer and Nozzle cover are the main parts that the design needs to be changed. This report suggest the needs for the IPS design modification and it would be reflected to the new IPS design which would accommodating test fuel pins

  8. Review Report on the Design of In-Pile Test Section(IPS)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong Min; Park, Kook Nam; Shim, Bong Sik; Lee, Chung Young; Chi, Dae Young; Park, Su Ki; Ahn, Sung Ho; Kim, Young Ki; Lee, Kye Hong; Kim, Kwan Hyun

    2009-01-15

    The In-Pile Test Section(IPS) accommodating fuel pins has loaded IR-1 hole in HANARO has double pressure vessel for the design conditions of 350 deg. C, 17.5 MPa and is composed of outer assembly and inner assembly. Dummy fuel, dummy fuel supports and Top flange are the main components in inner assembly and inner pressure vessel, outer pressure vessel and head are the components in outer assembly. The IPS at current status has dummy fuels and confirm the requirements for the IPS design improvements during the design, manufacturing and installation process. Head, Top Flange, Instrumentation Feed through, Lifting Eye, Fuel Carrier Leg, Retainer and Nozzle cover are the main parts that the design needs to be changed. This report suggest the needs for the IPS design modification and it would be reflected to the new IPS design which would accommodating test fuel pins.

  9. Aspects of the epidemiology of intestinal parasitosis (IP) in children ...

    African Journals Online (AJOL)

    Aspects of the epidemiology of intestinal parasitosis (IP) in children: ... Conclusion: The low level of knowledge, practices and perceptions of mothers concerning IP is a major cause for ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  10. Integrated control centre concepts for CANDU power plants

    International Nuclear Information System (INIS)

    Lupton, L.R.; Davey, E.C.; Lapointe, P.A.; Shah, R.R.

    1990-01-01

    The size and complexity of nuclear power plants has increased significantly in the last 20 years. There is general agreement that plant safety and power production can be enhanced if more operational support systems that are significantly different from the ones based on the more conventional technologies used in plant control rooms. In particular, artificial intelligence and related technologies will play a major role in the development of innovative methods for information processing and presentation. These technologies must be integrated into the overall management and control philosophy of the plant and not be treated as vehicles to implement point solutions. The underlying philosophy behind our approach is discussed in this paper. Operator support systems will integrate into the overall control philosophy by complementing the operator. Four support systems are described; each is a prototype of a system being considered for the CANDU 3 control centre

  11. Integrated control centre concepts for CANDU power plants

    Energy Technology Data Exchange (ETDEWEB)

    Lupton, L. R.; Davey, E. C.; Lapointe, P. A.; Shah, R. R.

    1990-01-15

    The size and complexity of nuclear power plants has increased significantly in the last 20 years. There is general agreement that plant safety and power production can be enhanced if more operational support systems that are significantly different from the ones based on the more conventional technologies used in plant control rooms. In particular, artificial intelligence and related technologies will play a major role in the development of innovative methods for information processing and presentation. These technologies must be integrated into the overall management and control philosophy of the plant and not be treated as vehicles to implement point solutions. The underlying philosophy behind our approach is discussed in this paper. Operator support systems will integrate into the overall control philosophy by complementing the operator. Four support systems are described; each is a prototype of a system being considered for the CANDU 3 control centre.

  12. Small Spacecraft Integrated Power System with Active Thermal Control

    Data.gov (United States)

    National Aeronautics and Space Administration — This project will develop an integrated power generation and energy storage system with an active thermal management system. Carbon fiber solar panels will contain...

  13. Integrated Micro-Power System (IMPS) Development at NASA Glenn Research Center

    Science.gov (United States)

    Wilt, David; Hepp, Aloysius; Moran, Matt; Jenkins, Phillip; Scheiman, David; Raffaelle, Ryne

    2003-01-01

    Glenn Research Center (GRC) has a long history of energy related technology developments for large space related power systems, including photovoltaics, thermo-mechanical energy conversion, electrochemical energy storage. mechanical energy storage, power management and distribution and power system design. Recently, many of these technologies have begun to be adapted for small, distributed power system applications or Integrated Micro-Power Systems (IMPS). This paper will describe the IMPS component and system demonstration efforts to date.

  14. Integration of power to gas/power to liquid in the ongoing transformation processes

    International Nuclear Information System (INIS)

    Purr, Katja; Osiek, Dirk; Lange, Martin

    2016-01-01

    The objective of this position paper is to assess from the current level of knowledge of the Federal Environment Agency the role and perspective of power to gas / power to Liquid (PtG / PtL) in a fully renewable energy system and in particular to appoint the challenges of integration and further development of this technique in the current transformation process in the next few years. Here also the comparison to other Power to X-options and their greenhouse gas reduction effect is shown. The geographic focus of the considerations is on Germany, knowing that a full renewable energy supply in Germany must be especially for economic reasons embedded in a long term international energy policy. [de

  15. 76 FR 81955 - Assessment Questionnaire-IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT)

    Science.gov (United States)

    2011-12-29

    ... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2011-0069] Assessment Questionnaire--IP Sector... will be posted without alteration at http://www.regulations.gov , including any personal information... managers often volunteer to conduct an automated self risk assessment. The requested questionnaire...

  16. Searching CLEF-IP by Strategy

    NARCIS (Netherlands)

    W. Alink (Wouter); R. Cornacchia (Roberto); A.P. de Vries (Arjen)

    2010-01-01

    htmlabstractTasks performed by intellectual property specialists are often ad hoc, and continuously require new approaches to search a collection of documents. We therefore investigate the benets of a visual `search strategy builder' to allow IP search experts to express their approach to

  17. Operation Modeling of Power Systems Integrated with Large-Scale New Energy Power Sources

    Directory of Open Access Journals (Sweden)

    Hui Li

    2016-10-01

    Full Text Available In the most current methods of probabilistic power system production simulation, the output characteristics of new energy power generation (NEPG has not been comprehensively considered. In this paper, the power output characteristics of wind power generation and photovoltaic power generation are firstly analyzed based on statistical methods according to their historical operating data. Then the characteristic indexes and the filtering principle of the NEPG historical output scenarios are introduced with the confidence level, and the calculation model of NEPG’s credible capacity is proposed. Based on this, taking the minimum production costs or the best energy-saving and emission-reduction effect as the optimization objective, the power system operation model with large-scale integration of new energy power generation (NEPG is established considering the power balance, the electricity balance and the peak balance. Besides, the constraints of the operating characteristics of different power generation types, the maintenance schedule, the load reservation, the emergency reservation, the water abandonment and the transmitting capacity between different areas are also considered. With the proposed power system operation model, the operation simulations are carried out based on the actual Northwest power grid of China, which resolves the new energy power accommodations considering different system operating conditions. The simulation results well verify the validity of the proposed power system operation model in the accommodation analysis for the power system which is penetrated with large scale NEPG.

  18. Single-tube linear DNA amplification (LinDA) for robust ChIP-seq

    NARCIS (Netherlands)

    Shankaranarayanan, P.; Mendoza-Parra, M.A.; Walia, M.; Wang, L.; Li, N.; Trindade, L.M.; Gronemeyer, H.

    2011-01-01

    Genome-wide profiling of transcription factors based on massive parallel sequencing of immunoprecipitated chromatin (ChIP-seq) requires nanogram amounts of DNA. Here we describe a high-fidelity, single-tube linear DNA amplification method (LinDA) for ChIP-seq and reChIP-seq with picogram DNA amounts

  19. Integrated societal risk assessment framework for nuclear power and renewable energy sources

    International Nuclear Information System (INIS)

    Lee, Sang Hun; Kang, Hyun Gook

    2015-01-01

    Recently, the estimation of the social cost of energy sources has been emphasized as various novel energy options become feasible in addition to conventional ones. In particular, the social cost of introducing measures to protect power-distribution systems from power-source instability and the cost of accident-risk response for various power sources must be investigated. To account for these risk factors, an integrated societal risk assessment framework, based on power-uncertainty analysis and accident-consequence analysis, is proposed. In this study, we applied the proposed framework to nuclear power plants, solar photovoltaic systems, and wind-turbine generators. The required capacity of gas-turbine power plants to be used as backup power facilities to compensate for fluctuations in the power output from the main power source was estimated based on the performance indicators of each power source. The average individual health risk per terawatt-hours (TWh) of electricity produced by each power source was quantitatively estimated by assessing accident frequency and the consequences of specific accident scenarios based on the probabilistic risk assessment methodology. This study is expected to provide insight into integrated societal risk analysis, and can be used to estimate the social cost of various power sources

  20. Integrated societal risk assessment framework for nuclear power and renewable energy sources

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Hun; Kang, Hyun Gook [Dept. of Nuclear and Quantum Engineering, KAIST, Daejeon (Korea, Republic of)

    2015-06-15

    Recently, the estimation of the social cost of energy sources has been emphasized as various novel energy options become feasible in addition to conventional ones. In particular, the social cost of introducing measures to protect power-distribution systems from power-source instability and the cost of accident-risk response for various power sources must be investigated. To account for these risk factors, an integrated societal risk assessment framework, based on power-uncertainty analysis and accident-consequence analysis, is proposed. In this study, we applied the proposed framework to nuclear power plants, solar photovoltaic systems, and wind-turbine generators. The required capacity of gas-turbine power plants to be used as backup power facilities to compensate for fluctuations in the power output from the main power source was estimated based on the performance indicators of each power source. The average individual health risk per terawatt-hours (TWh) of electricity produced by each power source was quantitatively estimated by assessing accident frequency and the consequences of specific accident scenarios based on the probabilistic risk assessment methodology. This study is expected to provide insight into integrated societal risk analysis, and can be used to estimate the social cost of various power sources.

  1. Adaptive control of power supply for integrated circuits

    NARCIS (Netherlands)

    2012-01-01

    The present invention relates to a circuit arrangement and method for controlling power supply in an integrated circuit wherein at least one working parameter of at least one electrically isolated circuit region (10) is monitored, and the conductivity of a variable resistor means is locally

  2. A Novel Smart Meter Controlling System with Dynamic IP Addresses

    DEFF Research Database (Denmark)

    Manembu, Pinrolinvic; Welang, Brammy; Kalua Lapu, Aditya

    2017-01-01

    Smart meters are the electronic devices for measuring energy consumption in real time. Usually, static public IP addresses are allocated to realize the point-to-point (P2P) communication and remote controlling for smart metering systems. This, however, restricts the wide deployment of smart meters......, due to the deficiency of public IP resources. This paper proposes a novel subscription-based communication architecture for the support of dynamic IP addresses and group controlling of smart meters. The paper evaluates the proposed architecture by comparing the traditional P2P architecture...

  3. OSI and TCP/IP

    Science.gov (United States)

    Randolph, Lynwood P.

    1994-01-01

    The Open Systems Interconnection Transmission Control Protocol/Internet Protocol (OSI TCP/IP) and the Government Open Systems Interconnection Profile (GOSIP) are compared and described in terms of Federal internetworking. The organization and functions of the Federal Internetworking Requirements Panel (FIRP) are discussed and the panel's conclusions and recommendations with respect to the standards and implementation of the National Information Infrastructure (NII) are presented.

  4. Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome

    Directory of Open Access Journals (Sweden)

    David A. Orlando

    2014-11-01

    Full Text Available Epigenomic profiling by chromatin immunoprecipitation coupled with massively parallel DNA sequencing (ChIP-seq is a prevailing methodology used to investigate chromatin-based regulation in biological systems such as human disease, but the lack of an empirical methodology to enable normalization among experiments has limited the precision and usefulness of this technique. Here, we describe a method called ChIP with reference exogenous genome (ChIP-Rx that allows one to perform genome-wide quantitative comparisons of histone modification status across cell populations using defined quantities of a reference epigenome. ChIP-Rx enables the discovery and quantification of dynamic epigenomic profiles across mammalian cells that would otherwise remain hidden using traditional normalization methods. We demonstrate the utility of this method for measuring epigenomic changes following chemical perturbations and show how reference normalization of ChIP-seq experiments enables the discovery of disease-relevant changes in histone modification occupancy.

  5. A physiological counterpoint to mechanistic estimates of "internal power" during cycling at different pedal rates

    DEFF Research Database (Denmark)

    Hansen, Ernst Albin; Jørgensen, Lars Vincents; Sjøgaard, Gisela

    2004-01-01

    metabolic variables and to perform a physiological evaluation of five different kinematic models for calculating IP in cycling. Results showed that IP was statistically different between the kinematic models applied. IP based on metabolic variables (IP(met)) was 15, 41, and 91 W at 61, 88, and 115 rpm...... significantly with pedal rate - leg movements accounting for the largest fraction. Further, external power (EP) affected IP significantly such that IP was larger at moderate than at low EP at the majority of the pedal rates applied but on average this difference was only 8%....

  6. Review of Energy Storage System for Wind Power Integration Support

    DEFF Research Database (Denmark)

    Zhao, Haoran; Wu, Qiuwei; Hu, Shuju

    2015-01-01

    -discharging characteristics, Energy Storage System (ESS) is considered as an effective tool to enhance the flexibility and controllability not only of a specific wind farm, but also of the entire grid. This paper reviews the state of the art of the ESS technologies for wind power integration support from different aspects......With the rapid growth of wind energy development and increasing wind power penetration level, it will be a big challenge to operate the power system with high wind power penetration securely and reliably due to the inherent variability and uncertainty of wind power. With the flexible charging...

  7. Integrative ChIP-seq/microarray analysis identifies a CTNNB1 target signature enriched in intestinal stem cells and colon cancer.

    Directory of Open Access Journals (Sweden)

    Kazuhide Watanabe

    Full Text Available Deregulation of canonical Wnt/CTNNB1 (beta-catenin pathway is one of the earliest events in the pathogenesis of colon cancer. Mutations in APC or CTNNB1 are highly frequent in colon cancer and cause aberrant stabilization of CTNNB1, which activates the transcription of Wnt target genes by binding to chromatin via the TCF/LEF transcription factors. Here we report an integrative analysis of genome-wide chromatin occupancy of CTNNB1 by chromatin immunoprecipitation coupled with high-throughput sequencing (ChIP-seq and gene expression profiling by microarray analysis upon RNAi-mediated knockdown of CTNNB1 in colon cancer cells.We observed 3629 CTNNB1 binding peaks across the genome and a significant correlation between CTNNB1 binding and knockdown-induced gene expression change. Our integrative analysis led to the discovery of a direct Wnt target signature composed of 162 genes. Gene ontology analysis of this signature revealed a significant enrichment of Wnt pathway genes, suggesting multiple feedback regulations of the pathway. We provide evidence that this gene signature partially overlaps with the Lgr5+ intestinal stem cell signature, and is significantly enriched in normal intestinal stem cells as well as in clinical colorectal cancer samples. Interestingly, while the expression of the CTNNB1 target gene set does not correlate with survival, elevated expression of negative feedback regulators within the signature predicts better prognosis.Our data provide a genome-wide view of chromatin occupancy and gene regulation of Wnt/CTNNB1 signaling in colon cancer cells.

  8. Control strategies for power distribution networks with electric vehicles integration

    DEFF Research Database (Denmark)

    Hu, Junjie

    of electrical energy. A smart grid can also be dened as an electricity network that can intelligently integrate the actions of all users connected to it - generators, consumers and those that do both - in order to eciently deliver sustainable, economic and secure electricity supplies. This thesis focuses...... of the ii market. To build a complete solution for integration of EVs into the distribution network, a price coordinated hierarchical scheduling system is proposed which can well characterize the involved actors in the smart grid. With this system, we demonstrate that it is possible to schedule the charging......Demand side resources, like electric vehicles (EVs), can become integral parts of a smart grids because instead of just consuming power they are capable of providing valuable services to power systems. EVs can be used to balance the intermittent renewable energy resources such as wind and solar...

  9. Scheduling Model for Renewable Energy Sources Integration in an Insular Power System

    Directory of Open Access Journals (Sweden)

    Gerardo J. Osório

    2018-01-01

    Full Text Available Insular power systems represent an asset and an excellent starting point for the development and analysis of innovative tools and technologies. The integration of renewable energy resources that has taken place in several islands in the south of Europe, particularly in Portugal, has brought more uncertainty to production management. In this work, an innovative scheduling model is proposed, which considers the integration of wind and solar resources in an insular power system in Portugal, with a strong conventional generation basis. This study aims to show the benefits of increasing the integration of renewable energy resources in this insular power system, and the objectives are related to minimizing the time for which conventional generation is in operation, maximizing profits, reducing production costs, and consequently, reducing greenhouse gas emissions.

  10. Real-time services in IP network architectures

    Science.gov (United States)

    Gilardi, Antonella

    1996-12-01

    The worldwide internet system seems to be the success key for the provision of real time multimedia services to both residential and business users and someone says that in such a way broadband networks will have a reason to exist. This new class of applications that use multiple media (voice, video and data) impose constraints to the global network nowadays consisting of subnets with various data links. The attention will be focused on the interconnection of IP non ATM and ATM networks. IETF and ATM forum are currently involved in the developing specifications suited to adapt the connectionless IP protocol to the connection oriented ATM protocol. First of all the link between the ATM and the IP service model has to be set in order to match the QoS and traffic requirements defined in the relative environment. A further significant topic is represented by the mapping of IP resource reservation model onto the ATM signalling and in the end it is necessary to define how the routing works when there are QoS parameters associated. This paper, considering only unicast applications, will examine the above issues taking as a starting point the situation where an host launches as call set up request with the relevant QoS and traffic descriptor and at some point a router at the edge of the ATM network has to decide how forwarding and request in order to establish an end to end link with the right capabilities. The aim is to compare the proposals emerging from different standard bodies to point out convergency or incompatibility.

  11. The Incredibly Long-Lived SN 2005ip

    Science.gov (United States)

    Fox, Ori

    2016-10-01

    Type IIn supernovae (SNe IIn) are defined by their relatively narrow spectral line features associated with a dense circumstellar medium (CSM) formed by the progenitor star. The nature of the progenitor and mass loss remains relatively unknown. Shock interaction with the dense CSM can often result in significant UV emission for several years post-explosion, thereby probing the CSM characteristics, progenitor mass loss history and, ultimately, the progenitor itself. The Type IIn SN 2005ip proves to be one of the most interesting and well-studied targets within this subclass. Compared to all other supernovae, SN 2005ip is the most luminous for its age. Now more than 11 years post-explosion, the SN has released >10^51 erg throughout its lifetime as the forward shock continues to collide with a dense CSM. Here we propose HST/STIS-MAMA UV observations of SN 2005ip to investigate the massive CSM. When accounting for the shock travel time, these observations will probe material lost from the progenitor more than 1000 years prior to the explosion. We already have a single HST/STIS spectrum of SN 2005ip from 2014, which was obtained while the shock was still within a higher mass regime. With just 5 orbits, a second spectrum will allow us to directly trace the evolution of the CSM and produce new constraints on the pre-SN mass-loss history. Coinciding with Cycle 24's UV Initiative, this program offers new insight regarding both the progenitor and explosion characteristics of the SN IIn subclass.

  12. Sate-of-the-art IP switching router architecture using SFQ technology

    International Nuclear Information System (INIS)

    Miyaho, N.; Miyahara, K.; Yamazaki, A.

    2006-01-01

    Taking the recent trend of rapid IP traffic increasing and QoS in the Internet into account, we propose an innovative IP router architecture from the viewpoint of minimum switching delay, switching capacity, QoS assurance for the next generation Internet services. We examined the IP router performance using superconductivity device simulator (WinS) assuming the future-generation Nb junction process and confirmed more than 300 GHz clock operation. For the evaluation of a novel IP switch architecture, we effectively apply the SFQ circuits using Josephson junctions to an extremely restricted function block in the switching node and a conventional semiconductor technology is also applied for the rest parts of the other function blocks inside it

  13. Large Scale Integration of Renewable Power Sources into the Vietnamese Power System

    Science.gov (United States)

    Kies, Alexander; Schyska, Bruno; Thanh Viet, Dinh; von Bremen, Lueder; Heinemann, Detlev; Schramm, Stefan

    2017-04-01

    The Vietnamese Power system is expected to expand considerably in upcoming decades. Power capacities installed are projected to grow from 39 GW in 2015 to 129.5 GW by 2030. Installed wind power capacities are expected to grow to 6 GW (0.8 GW 2015) and solar power capacities to 12 GW (0.85 GW 2015). This goes hand in hand with an increase of the renewable penetration in the power mix from 1.3% from wind and photovoltaics (PV) in 2015 to 5.4% by 2030. The overall potential for wind power in Vietnam is estimated to be around 24 GW. Moreover, the up-scaling of renewable energy sources was formulated as one of the priorized targets of the Vietnamese government in the National Power Development Plan VII. In this work, we investigate the transition of the Vietnamese power system towards high shares of renewables. For this purpose, we jointly optimise the expansion of renewable generation facilities for wind and PV, and the transmission grid within renewable build-up pathways until 2030 and beyond. To simulate the Vietnamese power system and its generation from renewable sources, we use highly spatially and temporally resolved historical weather and load data and the open source modelling toolbox Python for Power System Analysis (PyPSA). We show that the highest potential of renewable generation for wind and PV is observed in southern Vietnam and discuss the resulting need for transmission grid extensions in dependency of the optimal pathway. Furthermore, we show that the smoothing effect of wind power has several considerable beneficial effects and that the Vietnamese hydro power potential can be efficiently used to provide balancing opportunities. This work is part of the R&D Project "Analysis of the Large Scale Integration of Renewable Power into the Future Vietnamese Power System" (GIZ, 2016-2018).

  14. Integral power evaluation in fossil fuel power plants; Evaluacion energetica integral en unidades de centrales termoelectricas

    Energy Technology Data Exchange (ETDEWEB)

    Figueroa I, Luis R; Sanchez H, Laura E; Rodriguez M, Jose H [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico); Nebradt G, Jesus [Unidad de Investigacion y Desarrollo de la Subdireccion de Generacion de la Comision Federal de Electricidad, (Mexico)

    2006-07-01

    In this occasion, a methodology is presented that carries out an integral energy evaluation of fossil fuel power plants units (FFPPU) with the purpose of determining the root of the significant decrements of power produced soon after the annual maintenance service. This proposal, besides identifying the origin of the energy efficiency problems, offers information about the contributions of each one of the involved equipment in the total decrement of the unit. With this methodology, the maintenance focuses in the equipment that contributes to the greater energy loss. This document presents such methodology along with its application in a real case, results and necessary remedial actions, demonstrating that its application offers bases for the investment in corrective measures. [Spanish] En esta ocasion se presenta una metodologia que efectua una evaluacion energetica integral de las unidades de centrales termoelectricas (UCT) con el fin de determinar la raiz de los decrementos de potencia significativos producidos luego del servicio anual de mantenimiento. Dicha propuesta, ademas de identificar el origen de los problemas de eficiencia energetica, brinda informacion acerca de las aportaciones de cada uno de los equipos involucrados al decremento total de la unidad. Con esta metodologia, el mantenimiento se enfoca a los equipos que contribuyen a la mayor perdida de potencia. Este documento exhibe tal metodologia junto con su aplicacion en un caso real, resultados y las acciones correctivas necesarias, demostrando que su aplicacion ofrece bases para una inversion futura en medidas correctivas.

  15. Implantación de switching y ToIP sobre una red WAN

    OpenAIRE

    Pique Palacin, Ivan

    2013-01-01

    Este proyecto tiene como objeto el diseño y la implementación de servicios de comunicaciones de LAN (Switching) y Telefonía IP (ToIP), todos ellos integrados sobre una red WAN nacional ya existente y funcionando, gestionada por un ISP. Aquest projecte té com a objecte el disseny i la implementació de serveis de comunicacions de LAN (Switching) i telefonia IP (ToIP), tots ells integrats sobre una xarxa WAN nacional ja existent i funcionant, gestionada per un ISP. Bachelor thesis for the ...

  16. Integration of plug-in hybrid electric vehicles in a regional wind-thermal power system

    International Nuclear Information System (INIS)

    Goeransson, Lisa; Karlsson, Sten; Johnsson, Filip

    2010-01-01

    This study investigates consequences of integrating plug-in hybrid electric vehicles (PHEVs) in a wind-thermal power system supplied by one quarter of wind power and three quarters of thermal generation. Four different PHEV integration strategies, with different impacts on the total electric load profile, have been investigated. The study shows that PHEVs can reduce the CO 2 -emissions from the power system if actively integrated, whereas a passive approach to PHEV integration (i.e. letting people charge the car at will) is likely to result in an increase in emissions compared to a power system without PHEV load. The reduction in emissions under active PHEV integration strategies is due to a reduction in emissions related to thermal plant start-ups and part load operation. Emissions of the power sector are reduced with up to 4.7% compared to a system without PHEVs, according to the simulations. Allocating this emission reduction to the PHEV electricity consumption only, and assuming that the vehicles in electric mode is about 3 times as energy efficient as standard gasoline operation, total emissions from PHEVs would be less than half the emissions of a standard car, when running in electric mode.

  17. Controlling applied to information processing: quality management applied to IP projects and IP services; Informationsverarbeitungs-Controlling: Qualitaetsmanagement fuer IV-Projekte und fuer IV-Service

    Energy Technology Data Exchange (ETDEWEB)

    Becker, B. [Vereinigung Deutscher Elektrizitaetswerke e.V. (VDEW), Frankfurt am Main (Germany); Beckers, F. [Isar-Amperwerke AG, Muenchen (Germany); Dewald, N. [Bayernwerk AG, Muenchen (Germany); Hauffe, P. [Pfalzwerke AG, Ludwigshafen am Rhein (Germany); Hein, F. [EVS AG Stuttgart (Germany); Hoederath, M. [Vereinigte Elektrizitaetswerke Westfalen AG (VEW), Dortmund (Germany); Seyen, R. [Staedtische Werke Nuernberg GmbH (Germany)

    1998-01-12

    The working group on information processing (IP) basics (in German: `IV-Grundlagen`) has prepared this contribution dealing with controlling applied to information processing. This new report, on the one hand, takes into consideration the role of the organizational IP unit as one offering its services to all sections of a company. On the other hand, information processing as an operational infrastructure influencing all business processes becomes increasingly important with respect to the competitiveness of the EVU. Therefore, quality management applied to IP projects and IP services must support this development. (orig./RHM) [Deutsch] Der VDEW Arbeitskreis `IV-Grundlagen` hat einen Beitrag zum Controlling fuer die Informationsverarbeitung erstellt. Hier geht zum einen die Rolle der Organisationseinheit IV als Dienstleister fuer alle Unternehmensbereiche ein. Zum anderen gewinnt die Informationsverarbeitung als betriebliche Infrastruktur fuer alle Geschaeftsprozesse zunehmende Bedeutung fuer die Wettbewerbsfaehigkeit der EVU. Das Qualitaetsmanagement fuer IV-Projekte und fuer IV-Service muss dies unterstuetzen. (orig./RHM)

  18. Development of a real-time monitoring system and integration of different computer system in LHD experiments using IP multicast

    International Nuclear Information System (INIS)

    Emoto, Masahiko; Nakamura, Yukio; Teramachi, Yasuaki; Okumura, Haruhiko; Yamaguchi, Satarou

    2002-01-01

    There are several different computer systems in LHD (Large Helical Device) experiment, and therefore the coalition of these computers is a key to perform the experiment. Real-time monitoring system is also important because the long discharge is needed in the LHD experiment. In order to achieve these two requirements, the technique of IP multicast is adopted. The authors have developed three new systems, the first one is the real-time monitoring system, the next one is the delivery system of the shot number and the last one is the real-time notification system of the plasma data registration. The first system can deliver the real-time monitoring data to the LHD experimental LAN through the firewall of the LHD control LAN in NIFS. The other two systems are used to realize high coalition of the different computers in the LHD plasma experiment. We can conclude that IP multicast is very useful both in the LHD experiment and a future large plasma experiment from various experiences. (author)

  19. Integrated Three-Port Converters for Compact and Efficient Power Management, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — To meet the ever-increasing power demand of today's spacecraft systems, an integrated power electronics system capable of interfacing, and simultaneously...

  20. Integrated Three-Port Converters for Compact and Efficient Power Management, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — To meet the increasing power demand of today's spacecraft systems, an integrated power electronics system capable of interfacing, and simultaneously controlling,...

  1. Detection of a rare BCR-ABL tyrosine kinase fusion protein in H929 multiple myeloma cells using immunoprecipitation (IP)-tandem mass spectrometry (MS/MS).

    Science.gov (United States)

    Breitkopf, Susanne B; Yuan, Min; Pihan, German A; Asara, John M

    2012-10-02

    Hypothesis directed proteomics offers higher throughput over global analyses. We show that immunoprecipitation (IP)-tandem mass spectrometry (LC-MS/MS) in H929 multiple myeloma (MM) cancer cells led to the discovery of a rare and unexpected BCR-ABL fusion, informing a therapeutic intervention using imatinib (Gleevec). BCR-ABL is the driving mutation in chronic myeloid leukemia (CML) and is uncommon to other cancers. Three different IP-MS experiments central to cell signaling pathways were sufficient to discover a BCR-ABL fusion in H929 cells: phosphotyrosine (pY) peptide IP, p85 regulatory subunit of phosphoinositide-3-kinase (PI3K) IP, and the GRB2 adaptor IP. The pY peptides inform tyrosine kinase activity, p85 IP informs the activating adaptors and receptor tyrosine kinases (RTKs) involved in AKT activation and GRB2 IP identifies RTKs and adaptors leading to ERK activation. Integration of the bait-prey data from the three separate experiments identified the BCR-ABL protein complex, which was confirmed by biochemistry, cytogenetic methods, and DNA sequencing revealed the e14a2 fusion transcript. The tyrosine phosphatase SHP2 and the GAB2 adaptor protein, important for MAPK signaling, were common to all three IP-MS experiments. The comparative treatment of tyrosine kinase inhibitor (TKI) drugs revealed only imatinib, the standard of care in CML, was inhibitory to BCR-ABL leading to down-regulation of pERK and pS6K and inhibiting cell proliferation. These data suggest a model for directed proteomics from patient tumor samples for selecting the appropriate TKI drug(s) based on IP and LC-MS/MS. The data also suggest that MM patients, in addition to CML patients, may benefit from BCR-ABL diagnostic screening.

  2. Practical guidelines for the comprehensive analysis of ChIP-seq data.

    Directory of Open Access Journals (Sweden)

    Timothy Bailey

    Full Text Available Mapping the chromosomal locations of transcription factors, nucleosomes, histone modifications, chromatin remodeling enzymes, chaperones, and polymerases is one of the key tasks of modern biology, as evidenced by the Encyclopedia of DNA Elements (ENCODE Project. To this end, chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq is the standard methodology. Mapping such protein-DNA interactions in vivo using ChIP-seq presents multiple challenges not only in sample preparation and sequencing but also for computational analysis. Here, we present step-by-step guidelines for the computational analysis of ChIP-seq data. We address all the major steps in the analysis of ChIP-seq data: sequencing depth selection, quality checking, mapping, data normalization, assessment of reproducibility, peak calling, differential binding analysis, controlling the false discovery rate, peak annotation, visualization, and motif analysis. At each step in our guidelines we discuss some of the software tools most frequently used. We also highlight the challenges and problems associated with each step in ChIP-seq data analysis. We present a concise workflow for the analysis of ChIP-seq data in Figure 1 that complements and expands on the recommendations of the ENCODE and modENCODE projects. Each step in the workflow is described in detail in the following sections.

  3. The extended TRIP supporting VoIP routing reservation with distributed QoS

    Science.gov (United States)

    Wang, Furong; Wu, Ye

    2004-04-01

    In this paper, an existing protocol, i.e. TRIP (Telephony Routing over IP) is developed to provide distributed QoS when making resource reservations for VoIP services such as H.323, SIP. Enhanced LSs (location servers) are deployed in ITADs (IP Telephony Administrative Domains) to take in charge of intra-domain routing policy because of small propagation price. It is an easy way to find an IP telephone route for intra-domain VoIP media association and simultaneously possess intra-domain load balancing features. For those routing reservations bridging domains, inter-domain routing policy is responsible for finding the shortest inter-domain route with enough resources. I propose the routing preference policy based on QoS price when the session traffic is shaped by a token bucket, related QoS messages, and message cooperation.

  4. Vertical integration as a source of market power

    Energy Technology Data Exchange (ETDEWEB)

    Phelps, J.H.

    1981-11-01

    This paper has put forward a theory of vertial integration where the ability of a group of firms to engage in noncompetitive pricing is increased by altering conjectural variations. An analysis of conditions faced by major oil companies at refining indicated little likelihood of market power, short of a complex, secret price fixing agreement. Vertical integration to branded retail outlets appears to have created the ability to price noncompetitively without overt collusion. More interesting for vertical policy are the results on non price rivalry where excess profits appear to have been turned into social costs.

  5. VISA Final Report: Fully Integrated Power Electronic Systems in Automotive Electronics

    NARCIS (Netherlands)

    Waffenschmidt, E.

    2011-01-01

    This report summarizes the activities related to the public funded project “Vollintegrierte leistungselektronische Systeme in der Automobilelektronik – VISA” (Fully Integrated Power Electronic Systems in Automotive Electronics). Aim of the project is to investigate the integration of components into

  6. IP cores design from specifications to production modeling, verification, optimization, and protection

    CERN Document Server

    Mohamed, Khaled Salah

    2016-01-01

    This book describes the life cycle process of IP cores, from specification to production, including IP modeling, verification, optimization, and protection. Various trade-offs in the design process are discussed, including  those associated with many of the most common memory cores, controller IPs  and system-on-chip (SoC) buses. Readers will also benefit from the author’s practical coverage of new verification methodologies. such as bug localization, UVM, and scan-chain.  A SoC case study is presented to compare traditional verification with the new verification methodologies. ·         Discusses the entire life cycle process of IP cores, from specification to production, including IP modeling, verification, optimization, and protection; ·         Introduce a deep introduction for Verilog for both implementation and verification point of view.  ·         Demonstrates how to use IP in applications such as memory controllers and SoC buses. ·         Describes a new ver...

  7. Longevity and clinical performance of IPS-Empress ceramic restorations--a literature review.

    Science.gov (United States)

    El-Mowafy, Omar; Brochu, Jean-François

    2002-04-01

    A literature review of longevity and clinical performance of IPS-Empress restorations is presented. A MEDLINE search was conducted in fall 2000. Selection criteria were set so as to identify suitable clinical trials that were published in full and that had lasted more than 2 years. A total of 6 clinical trials on the performance of IPS-Empress inlays and onlays and a total of 3 clinical trials on the performance of IPS-Empress crowns were identified. Survival rates for IPS-Empress inlays and onlays ranged from 96% at 4.5 years to 91% at 7 years; most failures were due to bulk fracture. IPS-Empress crowns had a survival rate ranging from 92% to 99% at 3 to 3.5 years; crown failure was also mainly due to fracture. Dentists should inform their patients about these survival rates when offering such treatment. The use of IPS-Empress crowns in the posterior of the mouth is not recommended until the results of more long-term clinical trials are available.

  8. The CMOS integration of a power inverter

    Science.gov (United States)

    Mannarino, Eric Francis

    Due to their falling costs, the use of renewable energy systems is expanding around the world. These systems require the conversion of DC power into grid-synchronous AC power. Currently, the inverters that carry out this task are built using discrete transistors. TowerJazz Semiconductor Corp. has created a commercial CMOS process that allows for blocking voltages of up to 700 V, effectively removing the barrier to integrating power inverters onto a single chip. This thesis explores this process using two topologies. The first is a cell-based switched-capacitor topology first presented by Ke Zou. The second is a novel topology that explores the advantage of using a bused input-output system, as in digital electronics. Simulations run on both topologies confirm the high-efficiency demonstrated in Zou’s process as well as the advantage the bus-based system has in output voltage levels.

  9. 1 mm3-sized optical neural stimulator based on CMOS integrated photovoltaic power receiver

    Science.gov (United States)

    Tokuda, Takashi; Ishizu, Takaaki; Nattakarn, Wuthibenjaphonchai; Haruta, Makito; Noda, Toshihiko; Sasagawa, Kiyotaka; Sawan, Mohamad; Ohta, Jun

    2018-04-01

    In this work, we present a simple complementary metal-oxide semiconductor (CMOS)-controlled photovoltaic power-transfer platform that is suitable for very small (less than or equal to 1-2 mm) electronic devices such as implantable health-care devices or distributed nodes for the Internet of Things. We designed a 1.25 mm × 1.25 mm CMOS power receiver chip that contains integrated photovoltaic cells. We characterized the CMOS-integrated power receiver and successfully demonstrated blue light-emitting diode (LED) operation powered by infrared light. Then, we integrated the CMOS chip and a few off-chip components into a 1-mm3 implantable optogenetic stimulator, and demonstrated the operation of the device.

  10. Data exploration, quality control and statistical analysis of ChIP-exo/nexus experiments.

    Science.gov (United States)

    Welch, Rene; Chung, Dongjun; Grass, Jeffrey; Landick, Robert; Keles, Sündüz

    2017-09-06

    ChIP-exo/nexus experiments rely on innovative modifications of the commonly used ChIP-seq protocol for high resolution mapping of transcription factor binding sites. Although many aspects of the ChIP-exo data analysis are similar to those of ChIP-seq, these high throughput experiments pose a number of unique quality control and analysis challenges. We develop a novel statistical quality control pipeline and accompanying R/Bioconductor package, ChIPexoQual, to enable exploration and analysis of ChIP-exo and related experiments. ChIPexoQual evaluates a number of key issues including strand imbalance, library complexity, and signal enrichment of data. Assessment of these features are facilitated through diagnostic plots and summary statistics computed over regions of the genome with varying levels of coverage. We evaluated our QC pipeline with both large collections of public ChIP-exo/nexus data and multiple, new ChIP-exo datasets from Escherichia coli. ChIPexoQual analysis of these datasets resulted in guidelines for using these QC metrics across a wide range of sequencing depths and provided further insights for modelling ChIP-exo data. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  11. INTEGRATED PYROLYSIS COMBINED CYCLE BIOMASS POWER SYSTEM CONCEPT DEFINITION

    International Nuclear Information System (INIS)

    Sandvig, Eric; Walling, Gary; Brown, Robert C.; Pletka, Ryan; Radlein, Desmond; Johnson, Warren

    2003-01-01

    Advanced power systems based on integrated gasification/combined cycles (IGCC) are often presented as a solution to the present shortcomings of biomass as fuel. Although IGCC has been technically demonstrated at full scale, it has not been adopted for commercial power generation. Part of the reason for this situation is the continuing low price for coal. However, another significant barrier to IGCC is the high level of integration of this technology: the gas output from the gasifier must be perfectly matched to the energy demand of the gas turbine cycle. We are developing an alternative to IGCC for biomass power: the integrated (fast) pyrolysis/ combined cycle (IPCC). In this system solid biomass is converted into liquid rather than gaseous fuel. This liquid fuel, called bio-oil, is a mixture of oxygenated organic compounds and water that serves as fuel for a gas turbine topping cycle. Waste heat from the gas turbine provides thermal energy to the steam turbine bottoming cycle. Advantages of the biomass-fueled IPCC system include: combined cycle efficiency exceeding 37 percent efficiency for a system as small as 7.6 MW e ; absence of high pressure thermal reactors; decoupling of fuel processing and power generation; and opportunities for recovering value-added products from the bio-oil. This report provides a technical overview of the system including pyrolyzer design, fuel clean-up strategies, pyrolysate condenser design, opportunities for recovering pyrolysis byproducts, gas turbine cycle design, and Rankine steam cycle. The report also reviews the potential biomass fuel supply in Iowa, provide and economic analysis, and present a summery of benefits from the proposed system

  12. INTEGRATED PYROLYSIS COMBINED CYCLE BIOMASS POWER SYSTEM CONCEPT DEFINITION

    Energy Technology Data Exchange (ETDEWEB)

    Eric Sandvig; Gary Walling; Robert C. Brown; Ryan Pletka; Desmond Radlein; Warren Johnson

    2003-03-01

    Advanced power systems based on integrated gasification/combined cycles (IGCC) are often presented as a solution to the present shortcomings of biomass as fuel. Although IGCC has been technically demonstrated at full scale, it has not been adopted for commercial power generation. Part of the reason for this situation is the continuing low price for coal. However, another significant barrier to IGCC is the high level of integration of this technology: the gas output from the gasifier must be perfectly matched to the energy demand of the gas turbine cycle. We are developing an alternative to IGCC for biomass power: the integrated (fast) pyrolysis/ combined cycle (IPCC). In this system solid biomass is converted into liquid rather than gaseous fuel. This liquid fuel, called bio-oil, is a mixture of oxygenated organic compounds and water that serves as fuel for a gas turbine topping cycle. Waste heat from the gas turbine provides thermal energy to the steam turbine bottoming cycle. Advantages of the biomass-fueled IPCC system include: combined cycle efficiency exceeding 37 percent efficiency for a system as small as 7.6 MW{sub e}; absence of high pressure thermal reactors; decoupling of fuel processing and power generation; and opportunities for recovering value-added products from the bio-oil. This report provides a technical overview of the system including pyrolyzer design, fuel clean-up strategies, pyrolysate condenser design, opportunities for recovering pyrolysis byproducts, gas turbine cycle design, and Rankine steam cycle. The report also reviews the potential biomass fuel supply in Iowa, provide and economic analysis, and present a summery of benefits from the proposed system.

  13. Application of Power Systems Economics to Wind and Solar Power Integration

    OpenAIRE

    Mills, Andrew David

    2015-01-01

    The focus of this dissertation is the economic implications of the technical challenges of integrating variable generation, namely wind and solar, into the electric power system. The research is organized around three topics: short-term variability of wind and solar generation, changes in the economic value of wind and solar with increasing penetration, and the effectiveness of different measures at mitigating changes in economic value with increasing penetration levels. Early studies of PV g...

  14. A fully integrated, wide-load-range, high-power-conversion-efficiency switched capacitor DC-DC converter with adaptive bias comparator for ultra-low-power power management integrated circuit

    Science.gov (United States)

    Asano, Hiroki; Hirose, Tetsuya; Kojima, Yuta; Kuroki, Nobutaka; Numa, Masahiro

    2018-04-01

    In this paper, we present a wide-load-range switched-capacitor DC-DC buck converter with an adaptive bias comparator for ultra-low-power power management integrated circuit. The proposed converter is based on a conventional one and modified to operate in a wide load range by developing a load current monitor used in an adaptive bias comparator. Measurement results demonstrated that our proposed converter generates a 1.0 V output voltage from a 3.0 V input voltage at a load of up to 100 µA, which is 20 times higher than that of the conventional one. The power conversion efficiency was higher than 60% in the load range from 0.8 to 100 µA.

  15. An integrated low-voltage rated HTS DC power system with multifunctions to suit smart grids

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Jian Xun, E-mail: jxjin@uestc.edu.cn [Center of Applied Superconductivity, School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072 (China); Center of Applied Superconductivity and Electrical Engineering, School of Automation Engineering, University of Electronic Science and Technology of China, Chengdu 611731 (China); Chen, Xiao Yuan [School of Engineering, Sichuan Normal University, Chengdu 610101 (China); Qu, Ronghai; Fang, Hai Yang [School of Electrical and Electronic Engineering, Huazhong University of Science and Technology, Wuhan 430074 (China); Xin, Ying [Center of Applied Superconductivity, School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072 (China)

    2015-03-15

    Highlights: • A novel LVDC HTS power transmission network is presented. • An integrated power system is achieved by using HTS DC cable and SMES. • DC superconducting cable is verified to achieve self-acting fault current limitation. • SMES is verified to achieve fast-response buffering effect under a power fluctuation. • SMES is verified to achieve favorable load voltage protection effect under a fault. - Abstract: A low-voltage rated DC power transmission network integrated with superconducting cables (SCs) and superconducting magnetic energy storage (SMES) devices has been studied with analytic results presented. In addition to the properties of loss-less and high current transportation capacity, the effectively integrated system is formed with a self-acting fault current limitation feature of the SC and a buffering effect of the SMES to power fluctuations. The results obtained show that the integrated system can achieve high-quality power transmission under common power fluctuation conditions with an advanced self-protection feature under short circuit conditions, which is identified to suit especially the smart grid applications.

  16. Briefer assessment of social network drinking: A test of the Important People Instrument-5 (IP-5).

    Science.gov (United States)

    Hallgren, Kevin A; Barnett, Nancy P

    2016-12-01

    The Important People instrument (IP; Longabaugh et al., 2010) is one of the most commonly used measures of social network drinking. Although its reliability and validity are well-supported, the length of the instrument may limit its use in many settings. The present study evaluated whether a briefer, 5-person version of the IP (IP-5) adequately reproduces scores from the full IP. College freshmen (N = 1,053) reported their own past-month drinking, alcohol-related consequences, and information about drinking in their close social networks at baseline and 1 year later. From this we derived network members' drinking frequency, percentage of drinkers, and percentage of heavy drinkers, assessed for up to 10 (full IP) or 5 (IP-5) network members. We first modeled the expected concordance between full-IP scores and scores from simulated shorter IP instruments by sampling smaller subsets of network members from full IP data. Then, using quasi-experimental methods, we administered the full IP and IP-5 and compared the 2 instruments' score distributions and concurrent and year-lagged associations with participants' alcohol consumption and consequences. Most of the full-IP variance was reproduced from simulated shorter versions of the IP (ICCs ≥ 0.80). The full IP and IP-5 yielded similar score distributions, concurrent associations with drinking (r = 0.22 to 0.52), and year-lagged associations with drinking. The IP-5 retains most of the information about social network drinking from the full IP. The shorter instrument may be useful in clinical and research settings that require frequent measure administration, yielding greater temporal resolution for monitoring social network drinking. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  17. Real-time resource availability signaling in IP multimedia subsystem networks

    NARCIS (Netherlands)

    Ozcelebi, T.; Radovanovic, I.; Sengupta, D.

    2008-01-01

    IP Multimedia Subsystem (IMS) allows the use of unlicensed, non-dedicated and nondeterministic access networks for delivering IP multimedia services. Providing end-to-end Quality-of-Service (QoS) for resource demanding real-time services (e.g. real-time multimedia) over such networks is a

  18. Web-based IP telephony penetration system evaluating level of protection from attacks and threats

    OpenAIRE

    Vozňák, Miroslav; Řezáč, Filip

    2011-01-01

    This article deals with detection of threats in IP telephony, the authors developed a penetration testing system that is able to check up the level of protection from security threats in IP telephony. SIP is being widely used in building VoIP networks. Unlike the traditional telephone networks VoIP networks does not have a closed communication which makes communication medium vulnerable to all kinds of attacks from the in truders. The SIP server is a key component of VoIP infrastr...

  19. Implementasi Server VoIP Berbasis SIP Pada LAN Nirkabel

    Directory of Open Access Journals (Sweden)

    Mohammad Shoffa Al Arofat

    2013-03-01

    Full Text Available Voice over Internet Protocol (VoIP merupakan teknologi yang memungkinkan percakapan suara jarak jauh melalui protokol internet. Dalam telekomunikasi, diperlukan teknologi pensinyalan yang berguna untuk membangun, mengawasi, dan melepas hubungan antara dua titik. Salah satu teknologi pensinyalan yang banyak digunakan untuk VoIP adalah Session Initiation Protocol, dengan implementasinya yang berupa perangkat lunak Open SIP Server. Selain pensinyalan, ada beberapa parameter yang perlu diperhatikan dalam implementasi VoIP, yaitu Mean Opinion Score (MOS, network impairment, dan bandwidth. Pengujian dilakukan terhadap enam codec, yaitu G.722, PCMA, PCMU, Speex, GSM, dan BV16. Berdasarkan hasil analisis dapat diambil kesimpulan bahwa codec yang menggunakan bandwidth paling rendah adalah Speex (27,12 kbps; Rata-rata delay yang dihasilkan oleh sipdroid lebih baik daripada jitsi.

  20. Examples of modelling IP in AEM data: synthetic and real data

    DEFF Research Database (Denmark)

    Viezzoli, Andrea; Kaminskiy, Vladislav; Fiandaca, Gianluca

    There have been multiple evidences in the literature in the past several years of what has been referred to as IP effect in the Time Domain Airborne EM data (TDEM). This phenomenon is known to be responsible for incorrect inversion modelling of electrical resistivity, lower interpreted depth...... of investigation and lost information about chargeability of the subsurface as well as about other valuable parameters. Historically there have been many suggestions to account for the IP effect using the Cole-Cole model. In current paper we are showing the possibility to extract IP information from airborne TDEM...... with both high electrical conductivity and in resistive environments. Furthermore, modelling of IP effects allows corrected resistivity models. The Amakinskaya kimberlite pipe results highlight the relevance of chargeability for kimberlite exploration....

  1. Analisis Kualitas VoIP pada SCTP Menggunakan ECN dan AQM

    Directory of Open Access Journals (Sweden)

    La Surimi

    2015-07-01

    Abstract VoIP is the real time applications that are highly dependent on the quality of  delay and jitter, which it is difficult to be met by protocol that has reliable data transfer feature and  congestion control such as TCP. On the other hand the use of UDP that has no congestion control make chance of causing congestion in the network is very large. The use of SCTP as an alternative protocol was also not able to accommodate the weaknesses of TCP and UDP. Some research shows that repairs or modifications to the SCTP congestion control mechanism is needed. The Use of ECN and AQM in some studies show that these two mechanisms can reduce delay and jitter. This study tested the quality of VoIP over SCTP with ECN and AVQ, in NS2. Simulations carried out by independent replication technique, and the results showed that ECN and AVQ can increase the value of MOS VoIP calls significantly in non ideal network scenarios. This study also did comparison of SCTP MOS that uses ECN and AVQ with MOS values VoIP using TCP and UDP. The result showed that SCTP with ECN and AVQ outperform TCP but can not surpass UDP yet.   Keywords— VoIP, SCTP, ECN, AQM,AVQ.

  2. Technical Feasibility Study of Thermal Energy Storage Integration into the Conventional Power Plant Cycle

    Directory of Open Access Journals (Sweden)

    Jacek D. Wojcik

    2017-02-01

    Full Text Available The current load balance in the grid is managed mainly through peaking fossil-fuelled power plants that respond passively to the load changes. Intermittency, which comes from renewable energy sources, imposes additional requirements for even more flexible and faster responses from conventional power plants. A major challenge is to keep conventional generation running closest to the design condition with higher load factors and to avoid switching off periods if possible. Thermal energy storage (TES integration into the power plant process cycle is considered as a possible solution for this issue. In this article, a technical feasibility study of TES integration into a 375-MW subcritical oil-fired conventional power plant is presented. Retrofitting is considered in order to avoid major changes in the power plant process cycle. The concept is tested based on the complete power plant model implemented in the ProTRAX software environment. Steam and water parameters are assessed for different TES integration scenarios as a function of the plant load level. The best candidate points for heat extraction in the TES charging and discharging processes are evaluated. The results demonstrate that the integration of TES with power plant cycle is feasible and provide a provisional guidance for the design of the TES system that will result in the minimal influence on the power plant cycle.

  3. Coordinated Control of Multi-terminal DC Grid for Wind Power Integration

    DEFF Research Database (Denmark)

    Hao, Yu; Zhao, Haoran; Wu, Qiuwei

    2016-01-01

    Multi-terminal HVDC (MTDC) technology using voltage source converter (VSC) is a good option for wind power integration. Compared with point to point DC connection, MTDC provide better controllability based on different control strategies. In this paper, proportional-integral (PI) controllers...... with tuned PI parameters are designed to coordinate DC flow among the DC grid with good dynamic performance. In order to overcome the disadvantages of the conventional PI control, a simple adaptive PI control strategy is proposed based on the system transfer function. Case studies were conducted with PowerFactory....

  4. OffshoreDC DC grids for integration of large scale wind power

    DEFF Research Database (Denmark)

    Zeni, Lorenzo; Endegnanew, Atsede Gualu; Stamatiou, Georgios

    The present report summarizes the main findings of the Nordic Energy Research project “DC grids for large scale integration of offshore wind power – OffshoreDC”. The project is been funded by Nordic Energy Research through the TFI programme and was active between 2011 and 2016. The overall...... objective of the project was to drive the development of the VSC based HVDC technology for future large scale offshore grids, supporting a standardised and commercial development of the technology, and improving the opportunities for the technology to support power system integration of large scale offshore...

  5. Integrated societal risk assessment framework for nuclear power and renewable energy sources

    Directory of Open Access Journals (Sweden)

    Sang Hun Lee

    2015-06-01

    Full Text Available Recently, the estimation of the social cost of energy sources has been emphasized as various novel energy options become feasible in addition to conventional ones. In particular, the social cost of introducing measures to protect power-distribution systems from power-source instability and the cost of accident-risk response for various power sources must be investigated. To account for these risk factors, an integrated societal risk assessment framework, based on power-uncertainty analysis and accident-consequence analysis, is proposed. In this study, we applied the proposed framework to nuclear power plants, solar photovoltaic systems, and wind-turbine generators. The required capacity of gas-turbine power plants to be used as backup power facilities to compensate for fluctuations in the power output from the main power source was estimated based on the performance indicators of each power source. The average individual health risk per terawatt-hours (TWh of electricity produced by each power source was quantitatively estimated by assessing accident frequency and the consequences of specific accident scenarios based on the probabilistic risk assessment methodology. This study is expected to provide insight into integrated societal risk analysis, and can be used to estimate the social cost of various power sources.

  6. Integration of a nuclear power plant in electrical systems, alternative programs, optimization

    International Nuclear Information System (INIS)

    Souza, J.A.M. de.

    1991-01-01

    The problem of integration of a nuclear power plants in a electrical power system, to support the power demand of the system, and mainly also support the power demand at the critical period, I.E., peak demands, is analysed. The factors considered in this analysis are: the demand structure of the region, the availability of others power plants in the electrical net and the capacity factor. (author)

  7. Bayesian modeling of ChIP-chip data using latent variables.

    KAUST Repository

    Wu, Mingqi

    2009-10-26

    BACKGROUND: The ChIP-chip technology has been used in a wide range of biomedical studies, such as identification of human transcription factor binding sites, investigation of DNA methylation, and investigation of histone modifications in animals and plants. Various methods have been proposed in the literature for analyzing the ChIP-chip data, such as the sliding window methods, the hidden Markov model-based methods, and Bayesian methods. Although, due to the integrated consideration of uncertainty of the models and model parameters, Bayesian methods can potentially work better than the other two classes of methods, the existing Bayesian methods do not perform satisfactorily. They usually require multiple replicates or some extra experimental information to parametrize the model, and long CPU time due to involving of MCMC simulations. RESULTS: In this paper, we propose a Bayesian latent model for the ChIP-chip data. The new model mainly differs from the existing Bayesian models, such as the joint deconvolution model, the hierarchical gamma mixture model, and the Bayesian hierarchical model, in two respects. Firstly, it works on the difference between the averaged treatment and control samples. This enables the use of a simple model for the data, which avoids the probe-specific effect and the sample (control/treatment) effect. As a consequence, this enables an efficient MCMC simulation of the posterior distribution of the model, and also makes the model more robust to the outliers. Secondly, it models the neighboring dependence of probes by introducing a latent indicator vector. A truncated Poisson prior distribution is assumed for the latent indicator variable, with the rationale being justified at length. CONCLUSION: The Bayesian latent method is successfully applied to real and ten simulated datasets, with comparisons with some of the existing Bayesian methods, hidden Markov model methods, and sliding window methods. The numerical results indicate that the

  8. Integrated multiscale simulation of combined heat and power based district heating system

    International Nuclear Information System (INIS)

    Li, Peifeng; Nord, Natasa; Ertesvåg, Ivar Ståle; Ge, Zhihua; Yang, Zhiping; Yang, Yongping

    2015-01-01

    Highlights: • Simulation of power plant, district heating network and heat users in detail and integrated. • Coupled calculation and analysis of the heat and pressure losses of the district heating network. • District heating is not preferable for very low heat load due to relatively high heat loss. • Lower design supply temperatures of the district heating network give higher system efficiency. - Abstract: Many studies have been carried out separately on combined heat and power and district heating. However, little work has been done considering the heat source, the district heating network and the heat users simultaneously, especially when it comes to the heating system with large-scale combined heat and power plant. For the purpose of energy conservation, it is very important to know well the system performance of the integrated heating system from the very primary fuel input to the terminal heat users. This paper set up a model of 300 MW electric power rated air-cooled combined heat and power plant using Ebsilon software, which was validated according to the design data from the turbine manufacturer. Then, the model of heating network and heat users were developed based on the fundamental theories of fluid mechanics and heat transfer. Finally the combined heat and power based district heating system was obtained and the system performances within multiscale scope of the system were analyzed using the developed Ebsilon model. Topics with regard to the heat loss, the pressure drop, the pump power consumption and the supply temperatures of the district heating network were discussed. Besides, the operational issues of the integrated system were also researched. Several useful conclusions were drawn. It was found that a lower design primary supply temperature of the district heating network would give a higher seasonal energy efficiency of the integrated system throughout the whole heating season. Moreover, it was not always right to relate low design

  9. VoIP interconnection ; between Internet, Cable, Mobile and Fixed Worlds

    NARCIS (Netherlands)

    Deventer, M.O. van; Keesmaat, I.

    2005-01-01

    Four worlds on their own that hardly interconnect; All use SIP, but differently - Internet world - Mobile world - Cable world - Fixed world - At most, only basic voice service will interoperate between those worlds In recent years, VoIP/multimedia services (VoIP: Voice over Internet Protocol) have

  10. Dynamic Optimal Energy Flow in the Integrated Natural Gas and Electrical Power Systems

    DEFF Research Database (Denmark)

    Fang, Jiakun; Zeng, Qing; Ai, Xiaomeng

    2018-01-01

    . Simulation on the test case illustrates the success of the modelling and the beneficial roles of the power-to-gas are analyzed. The proposed model can be used in the decision support for both planning and operation of the coordinated natural gas and electrical power systems.......This work focuses on the optimal operation of the integrated gas and electrical power system with bi-directional energy conversion. Considering the different response times of the gas and power systems, the transient gas flow and steady- state power flow are combined to formulate the dynamic...... optimal energy flow in the integrated gas and power systems. With proper assumptions and simplifications, the problem is transformed into a single stage linear programming. And only a single stage linear programming is needed to obtain the optimal operation strategy for both gas and power systems...

  11. A Learning-Based Approach for IP Geolocation

    Science.gov (United States)

    Eriksson, Brian; Barford, Paul; Sommers, Joel; Nowak, Robert

    The ability to pinpoint the geographic location of IP hosts is compelling for applications such as on-line advertising and network attack diagnosis. While prior methods can accurately identify the location of hosts in some regions of the Internet, they produce erroneous results when the delay or topology measurement on which they are based is limited. The hypothesis of our work is that the accuracy of IP geolocation can be improved through the creation of a flexible analytic framework that accommodates different types of geolocation information. In this paper, we describe a new framework for IP geolocation that reduces to a machine-learning classification problem. Our methodology considers a set of lightweight measurements from a set of known monitors to a target, and then classifies the location of that target based on the most probable geographic region given probability densities learned from a training set. For this study, we employ a Naive Bayes framework that has low computational complexity and enables additional environmental information to be easily added to enhance the classification process. To demonstrate the feasibility and accuracy of our approach, we test IP geolocation on over 16,000 routers given ping measurements from 78 monitors with known geographic placement. Our results show that the simple application of our method improves geolocation accuracy for over 96% of the nodes identified in our data set, with on average accuracy 70 miles closer to the true geographic location versus prior constraint-based geolocation. These results highlight the promise of our method and indicate how future expansion of the classifier can lead to further improvements in geolocation accuracy.

  12. Optimal use of tandem biotin and V5 tags in ChIP assays

    Directory of Open Access Journals (Sweden)

    Krpic Sanja

    2009-02-01

    Full Text Available Abstract Background Chromatin immunoprecipitation (ChIP assays coupled to genome arrays (Chip-on-chip or massive parallel sequencing (ChIP-seq lead to the genome wide identification of binding sites of chromatin associated proteins. However, the highly variable quality of antibodies and the availability of epitopes in crosslinked chromatin can compromise genomic ChIP outcomes. Epitope tags have often been used as more reliable alternatives. In addition, we have employed protein in vivo biotinylation tagging as a very high affinity alternative to antibodies. In this paper we describe the optimization of biotinylation tagging for ChIP and its coupling to a known epitope tag in providing a reliable and efficient alternative to antibodies. Results Using the biotin tagged erythroid transcription factor GATA-1 as example, we describe several optimization steps for the application of the high affinity biotin streptavidin system in ChIP. We find that the omission of SDS during sonication, the use of fish skin gelatin as blocking agent and choice of streptavidin beads can lead to significantly improved ChIP enrichments and lower background compared to antibodies. We also show that the V5 epitope tag performs equally well under the conditions worked out for streptavidin ChIP and that it may suffer less from the effects of formaldehyde crosslinking. Conclusion The combined use of the very high affinity biotin tag with the less sensitive to crosslinking V5 tag provides for a flexible ChIP platform with potential implications in ChIP sequencing outcomes.

  13. Optimal use of tandem biotin and V5 tags in ChIP assays

    Science.gov (United States)

    Kolodziej, Katarzyna E; Pourfarzad, Farzin; de Boer, Ernie; Krpic, Sanja; Grosveld, Frank; Strouboulis, John

    2009-01-01

    Background Chromatin immunoprecipitation (ChIP) assays coupled to genome arrays (Chip-on-chip) or massive parallel sequencing (ChIP-seq) lead to the genome wide identification of binding sites of chromatin associated proteins. However, the highly variable quality of antibodies and the availability of epitopes in crosslinked chromatin can compromise genomic ChIP outcomes. Epitope tags have often been used as more reliable alternatives. In addition, we have employed protein in vivo biotinylation tagging as a very high affinity alternative to antibodies. In this paper we describe the optimization of biotinylation tagging for ChIP and its coupling to a known epitope tag in providing a reliable and efficient alternative to antibodies. Results Using the biotin tagged erythroid transcription factor GATA-1 as example, we describe several optimization steps for the application of the high affinity biotin streptavidin system in ChIP. We find that the omission of SDS during sonication, the use of fish skin gelatin as blocking agent and choice of streptavidin beads can lead to significantly improved ChIP enrichments and lower background compared to antibodies. We also show that the V5 epitope tag performs equally well under the conditions worked out for streptavidin ChIP and that it may suffer less from the effects of formaldehyde crosslinking. Conclusion The combined use of the very high affinity biotin tag with the less sensitive to crosslinking V5 tag provides for a flexible ChIP platform with potential implications in ChIP sequencing outcomes. PMID:19196479

  14. Genome wide binding (ChIP-Seq of murine Bapx1 and Sox9 proteins in vivo and in vitro

    Directory of Open Access Journals (Sweden)

    Sumantra Chatterjee

    2016-12-01

    Full Text Available This work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing cell type specification and the generation of tissues and subsequent organs [1]. Our earlier work identified the role of the DNA-binding homeodomain containing protein Bapx1/Nkx3.2 in midgestation murine embryos. Microarray analysis of EGFP-tagged cells (both wildtype and null was integrated using ChIP-Seq analysis of Bapx1/Nkx3.2 and Sox9 DNA-binding proteins in living tissue.

  15. Emancipating Intellectual Property from Proprietarianism: Drahos, Foucault, and a Quasi-Genealogy of IP

    Directory of Open Access Journals (Sweden)

    Wendyl Luna

    2018-01-01

    Full Text Available This paper argues that Peter Drahos undertakes a partial Foucauldian genealogy by emancipating intellectual property (IP from proprietarianism. He demonstrates the dominance of proprietarianism in IP by drawing sample practices from trademark, copyright, and patent laws, and then seeks to displace the proprietarian dominance with instrumentalism, which reconstitutes IP as a “liberty-intruding privilege.” Ironically, despite doing a genealogy, Drahos does not eradicate sovereignty altogether as Michel Foucault insists, but instead determines IP as a “sovereignty mechanism” that has a “sovereignty effect.” After explaining what Foucauldian genealogy is, the paper will explain how Drahos undertakes a genealogy of IP, while highlighting the limitations of Drahos’ analysis from a Foucauldian perspective.

  16. IP-10 release assays in the diagnosis of tuberculosis infection

    DEFF Research Database (Denmark)

    Ruhwald, Morten; Aabye, Martine G; Ravn, Pernille

    2012-01-01

    The current state-of-the-art tests for infection with Mycobacterium tuberculosis - the IFN-γ release assays - rely on accurate measurement of the cytokine IFN-γ. Many other potential biomarkers are expressed in concert with IFN-γ, and IP-10 in particular has shown promising results. IP-10...

  17. Integrated packaging of multiple double sided cooling planar bond power modules

    Science.gov (United States)

    Liang, Zhenxian

    2018-04-10

    An integrated double sided cooled power module has one or multiple phase legs configuration including one or more planar power packages, each planar power package having an upper power switch unit and a lower power switch unit directly bonded and interconnected between two insulated power substrates, and further sandwiched between two heat exchangers via direct bonds. A segmented coolant manifold is interposed with the one or more planar power packages and creates a sealed enclosure that defines a coolant inlet, a coolant outlet and a coolant flow path between the inlet and the outlet. A coolant circulates along the flow path to remove heat and increase the power density of the power module.

  18. EQuIP-ped for Success

    Science.gov (United States)

    Ewing, Molly

    2015-01-01

    The Educators Evaluating the Quality of Instructional Products (EQuIP) Rubric for science is a new tool for science educators that provides criteria by which to examine the alignment and overall quality of lessons and units with respect to the "Next Generation Science Standards" ("NGSS"). The rubric criteria are divided into…

  19. (S)-(+)-Ipsdienol: Interspecific Inhibition of Ips latidens (LeConte) by Ips pini (Say) (Coleoptera: Scolytidae)

    Science.gov (United States)

    Daniel R. Miller; John H. Borden

    1992-01-01

    In south-central British Columbia, the attraction of Ips latidens (LeConte) to its pheromone, ipsenol, was inhibited by (S)-(+)-ipsdienol, a pheromone for I. pini (Say). (R)-(-)-Ipsdienol had no effect on I. latidens. (S)-(+)-lpsdienol probably plays a role in interspecific communication between the two species...

  20. Analisis Data Digital Evidence pada Layanan Voice Over Internet Protocol (VoIP

    Directory of Open Access Journals (Sweden)

    Muhamad Arsad Adam

    2016-11-01

    Full Text Available Teknologi  VoIP  (Voice  Over  Internet  Protocol merupakan  teknologi  yang  mampu  melewatkan  panggilan  suara, video  dan  data  dalam  jaringan  IP.  Voice  over  Internet  Protocol (VoIP  dalam  teknologi  komunikasi  cukup  signifikan  sehingga tidak  terlepas  dari  kejahatan  cybercrime,  Teknologi  VoIP  dapat disalahgunakan  untuk  melakukan  tindakan  kejahatan  jarak  jauh sehingga  diperlukan  langkah-langkah  investigasi  jika  terjadi masalah.  Menemukan  artefact  pada  Infrastruktur  VoIP merupakan tantangan tersendiri. WireSharks salah satu tool yang digunakan  dalam  investigasi  ini.  Metode  yang  digunakan  adalah DFIF  yang  terdiri  tahapan  adalah  Collection,  Examination, Analysis, dan Report and Documentation. Investigasi pada layanan VoIP  dapat  berhasil  dilakukan  dengan  menemukan  data  digital evidence  di  layer  5.  Tujuan  Penelitian  ini  yaitu  Mengetahui Karakteristik Data Digital berupa suara pada layanan Voice Over IP  dan  Menganalisis  Data  Digital  berupa  suara  pada  layanan Voice Over IP. Hasil dari penelitian ini barang bukti digital yang berupa  percakapan  yang  dapat  dipertanggungjawabkan  dalam pengadilan..Kata kunci— Data, Evidence, Forensik,Network, VoIP

  1. Impact of time-domain IP pulse length on measured data and inverted models

    DEFF Research Database (Denmark)

    Olsson, P. I.; Fiandaca, G.; Dahlin, T.

    2015-01-01

    The duration of time domain (TD) induced polarization (IP) current injections has significant impact on the acquired IP data as well as on the inversion models, if the standard evaluation procedure is followed. However, it is still possible to retrieve similar inversion models if the waveform...... of the injected current and the IP response waveform are included in the inversion. The on-time also generally affects the signal-tonoise ratio (SNR) where an increased on-time gives higher SNR for the IP data....

  2. Expected Future Conditions for Secure Power Operation with Large Scale of RES Integration

    International Nuclear Information System (INIS)

    Majstrovic, G.; Majstrovic, M.; Sutlovic, E.

    2015-01-01

    EU energy strategy is strongly focused on the large scale integration of renewable energy sources. The most dominant part here is taken by variable sources - wind power plants. Grid integration of intermittent sources along with keeping the system stable and secure is one of the biggest challenges for the TSOs. This part is often neglected by the energy policy makers, so this paper deals with expected future conditions for secure power system operation with large scale wind integration. It gives an overview of expected wind integration development in EU, as well as expected P/f regulation and control needs. The paper is concluded with several recommendations. (author).

  3. A Brazilian version of the "Children's Interview for Psychiatric Syndromes" (ChIPS A versão brasileira do "Children's Interview for Psychiatric Syndromes" (ChIPS

    Directory of Open Access Journals (Sweden)

    Isabella G. S. de Souza

    2009-01-01

    Full Text Available OBJETIVE: The advance of research in child and adolescent psychiatry in Brazil heavily depends on the existence of instruments for the investigation of psychiatric syndromes adapted to Brazilian Portuguese. METHODS: This article describes a careful process of translation of the Children's Interview for Psychiatric Syndromes for the purpose of use in research in Brazil. The Children's Interview for Psychiatric Syndromes has a version for parents (P-ChIPs and a version for children (ChIPS. In this article, the sections of P-ChIPS referring to attention-deficit hyperactivity disorder, oppositional-defiant disorder, conduct disorder, mania/hypomania, anorexia nervosa, bulimia nervosa and psychotic disorders were translated to Brazilian Portuguese. The sections of the ChIPS referring to substance use disorders, social anxiety disorder, specific phobias, obsessive-compulsive disorder, generalized anxiety disoder, separation anxiety disorder, post-traumatic disorders and depression/dysthimia were also adapted. Each section was translated by two independent translators and later discussed in a committee composed of experts in the field of Psychiatry and a professional of the field of linguistics. RESULT: A final version containing an interview for the main psychiatric syndromes was defined. CONCLUSION: The translated P-ChIPS is a helpful instrument in children and adolescent clinical evaluation.OBJETIVO: O avanço em pesquisa em psiquiatria da infância e adolescência no Brasil depende da existência de instrumentos para a investigação de síndromes psiquiátricas adaptadas à Língua Portuguesa. Este artigo descreve um cuidadoso processo de tradução do Children´s Interview for Psychiatric Syndromes para o uso em pesquisa no Brasil. MÉTODOS: O Children´s Interview for Psychiatric Syndromes tem uma versão para pais (P-ChIPs e uma versão para as crianças (ChIPs. Nesse artigo, as seções do P-ChIPs referentes ao transtorno do déficit de aten

  4. Planning construction of integrative schedule management for nuclear power project

    International Nuclear Information System (INIS)

    Zeng Zhenglin; Wang Wenying; Peng Fei

    2012-01-01

    This paper introduces the planning construction of integrative schedule management for Nuclear Power Project. It details schedule management system and the requirement of schedulers and the mode of three schedule management flats. And analysis it combing with the implementation of construction water and all special schedules before FCD to further propose the improving and researching direction for the integrative schedule management. (authors)

  5. Considerations on VoIP Throughput in 802.11 Networks

    Directory of Open Access Journals (Sweden)

    POTORAC, A. D.

    2009-10-01

    Full Text Available Voice data packets have to arrive at the destination in time, with a defined cadence and with low and constant delay in order to allow the real time voice reconstruction. From this point of view, transmitting voice over IP networks is the most sensitive category of applications, especially when wireless medium is involved. The paper discusses the possibilities of transmitting the maximum number of simultaneous voice streams over 802.11 wireless networks considering the main factors which impact with VoIP throughput, in a basic scenario. Starting from a proposed communication model, the number of simultaneous possible VoIP sessions is calculated, taking into consideration the contribution of the protocol overheads, the security overheads, the PHY level timings and the CODEC proprieties. Numerical results are generated and compared.

  6. Large-scale integration of wind power into the existing Chinese energy system

    DEFF Research Database (Denmark)

    Liu, Wen; Lund, Henrik; Mathiesen, Brian Vad

    2011-01-01

    stability, the maximum feasible wind power penetration in the existing Chinese energy system is approximately 26% from both technical and economic points of view. A fuel efficiency decrease occurred when increasing wind power penetration in the system, due to its rigid power supply structure and the task......This paper presents the ability of the existing Chinese energy system to integrate wind power and explores how the Chinese energy system needs to prepare itself in order to integrate more fluctuating renewable energy in the future. With this purpose in mind, a model of the Chinese energy system has...... been constructed by using EnergyPLAN based on the year 2007, which has then been used for investigating three issues. Firstly, the accuracy of the model itself has been examined and then the maximum feasible wind power penetration in the existing energy system has been identified. Finally, barriers...

  7. Threshold-based generic scheme for encrypted and tunneled Voice Flows Detection over IP Networks

    Directory of Open Access Journals (Sweden)

    M. Mazhar U. Rathore

    2015-07-01

    Full Text Available VoIP usage is rapidly growing due to its cost effectiveness, dramatic functionality over the traditional telephone network and its compatibility with public switched telephone network (PSTN. In some countries, like Pakistan, the commercial usage of VoIP is prohibited. Internet service providers (ISPs and telecommunication authorities are interested in detecting VoIP calls to either block or prioritize them. So detection of VoIP calls is important for both types of authorities. Signature-based, port-based, and pattern-based VoIP detection techniques are inefficient due to complex and confidential security and tunneling mechanisms used by VoIP. In this paper, we propose a generic, robust, efficient, and practically implementable statistical analysis-based solution to identify encrypted, non-encrypted, or tunneled VoIP media (voice flows using threshold values of flow statistical parameters. We have made a comparison with existing techniques and evaluated our system with respect to accuracy and efficiency. Our system has 97.54% direct rate and .00015% false positive rate.

  8. Integrating wind output with bulk power operations and wholesale electricity markets

    International Nuclear Information System (INIS)

    Hirst, E.

    2002-01-01

    Wind farms have three characteristics that complicate their widespread application as an electricity resource: limited control, unpredictability and variability. Therefore the integration of wind output into bulk power electric systems is qualitatively different from that of other types of generators. The electric system operator must move other generators up or down to offset the time-varying wind fluctuations. Such movements raise the costs of fuel and maintenance for these other generators. Not only is wind power different, it is new. The operators of bulk power systems have limited experience in integrating wind output into the larger system. As a consequence, market rules that treat wind fairly - neither subsidizing nor penalizing its operation - have not yet been developed. The lack of data and analytical methods encourages wind advocates and sceptics to rely primarily on their biases and beliefs in suggesting how wind should be integrated into bulk power systems. This project helps fill this data and analysis gap. Specifically, it develops and applies a quantitative method for the integration of a wind resource into a large electric system. The method permits wind to bid its output into a short-term forward market (specifically, an hour-ahead energy market) or to appear in real time and accept only intrahour and hourly imbalance payments for the unscheduled energy it delivers to the system. Finally, the method analyses the short-term (minute-to-minute) variation in wind output to determine the regulation requirement the wind resource imposes on the electrical system. (author)

  9. System Integration of Distributed Power for Complete Building Systems: Phase 2 Report

    Energy Technology Data Exchange (ETDEWEB)

    Kramer, R.

    2003-12-01

    This report describes NiSource Energy Technologies Inc.'s second year of a planned 3-year effort to advance distributed power development, deployment, and integration. Its long-term goal is to design ways to extend distributed generation into the physical design and controls of buildings. NET worked to meet this goal through advances in the implementation and control of combined heat and power systems in end-user environments and a further understanding of electric interconnection and siting issues. The specific objective of work under this subcontract is to identify the system integration and implementation issues of DG and develop and test potential solutions to these issues. In addition, recommendations are made to resolve identified issues that may hinder or slow the integration of integrated energy systems into the national energy picture.

  10. Optimal design of an IP/MPLS over DWDM network

    Directory of Open Access Journals (Sweden)

    Eduardo Canale

    2014-04-01

    Full Text Available Different approaches for deploying resilient optical networks of low cost constitute a traditional group of NP-Hard problems that have been widely studied. Most of them are based on the construction of low cost networks that fulfill connectivity constraints. However, recent trends to virtualize optical networks over the legacy fiber infrastructure, modified the nature of network design problems and turned inappropriate many of these models and algorithms. In this paper we study a design problem arising from the deployment of an IP/MPLS network over an existing DWDM infrastructure. Besides cost and resiliency, this problem integrates traffic and capacity constraints. We present: an integer programming formulation for the problem, theoretical results, and describe how several metaheuristics were applied in order to find good quality solutions, for a real application case of a telecommunications company.

  11. Consistency among integral measurements of aggregate decay heat power

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, H.; Sagisaka, M.; Oyamatsu, K.; Kukita, Y. [Nagoya Univ. (Japan)

    1998-03-01

    Persisting discrepancies between summation calculations and integral measurements force us to assume large uncertainties in the recommended decay heat power. In this paper, we develop a hybrid method to calculate the decay heat power of a fissioning system from those of different fissioning systems. Then, this method is applied to examine consistency among measured decay heat powers of {sup 232}Th, {sup 233}U, {sup 235}U, {sup 238}U and {sup 239}Pu at YAYOI. The consistency among the measured values are found to be satisfied for the {beta} component and fairly well for the {gamma} component, except for cooling times longer than 4000 s. (author)

  12. In situ remediation integrated program: Success through teamwork

    International Nuclear Information System (INIS)

    Peterson, M.E.

    1994-08-01

    The In Situ Remediation Integrated Program (ISR IP), managed under the US Department of Energy's (DOE) Office of Technology Development, focuses research and development efforts on the in-place treatment of contaminated environmental media, such as soil and groundwater, and the containment of contaminants to prevent the contaminants from spreading through the environment. As described here, specific ISR IP projects are advancing the application of in situ technologies to the demonstration point, providing developed technologies to customers within DOE. The ISR IP has also taken a lead role in assessing and supporting innovative technologies that may have application to DOE

  13. Integrative Psychotherapy ‘Revisited’

    OpenAIRE

    Marye O’Reilly-Knapp

    2017-01-01

    This article revisits aspects of the theory and methods of Integrative Psychotherapy as written and discussed by Richard G. Erskine, PhD and others. A case study demonstrates the use of Integrative Psychotherapy as the basis for therapeutic interventions that allow the client to interpret early experiences of relational failures, via a relationally based psychotherapy. Revisiting the theory and methods of Integrative Psychotherapy served to further validate the core of IP and its value as a ...

  14. Myricetin stimulates the absorption of the pro-carcinogen PhIP

    NARCIS (Netherlands)

    Schutte, M.E.; Sandt, J.J.M. van de; Alink, G.M.; Groten, J.P.; Rietjens, I.M.C.M.

    2006-01-01

    The effect of the flavonoid myricetin on the transport of the pro-carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through differentiated Caco-2 monolayers, a model for the intestinal epithelium, is described. Myricetin causes an increase of the transport of PhIP from the apical to

  15. Universal Space IP Transparent Proxy, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Communications applications are strategically moving toward Internet Protocol-based architectures and technologies. Despite IP's huge potential, (e.g. cost...

  16. 47 CFR 64.606 - VRS and IP Relay provider and TRS program certification.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false VRS and IP Relay provider and TRS program... Services and Related Customer Premises Equipment for Persons With Disabilities § 64.606 VRS and IP Relay... including notification in the Federal Register. (2) VRS and IP Relay provider. Any entity desiring to...

  17. Impact of integrating wind power in the Norwegian power system

    International Nuclear Information System (INIS)

    Tande, John Olav

    2006-04-01

    Wind power may in the future constitute a significant part of the Norwegian electricity supply. 20 TWh annual wind generation is a realistic goal for 2020 assuming wind farms on-land and offshore. The development of grid codes for wind farms is sound. It is recognising that large wind farms are basically power plants and may participate in securing efficient and stable power system operation. Modern wind farms may control the reactive power or voltage as any other power plant, and may also control active power or frequency as long as wind conditions permits. Grid code requirements must however be carefully assessed and possibly adjusted over time aiming for overall least cost solutions. Development of wind farms are today to some degree hindered by conservative assumptions being made on operation of wind farms in areas with limited power transfer capacity. By accepting temporary grid congestions, however, a large increase installed wind power is viable. For grid congestion that appears a few hours per year only, the cost of lost generation will be modest and may be economic over the alternatives of limiting wind farm capacities or increasing the grid transfer capacity. Wind generation impact on power system operation and adequacy will be overall positive. Combining wind and hydro provides for a more stable annual energy supply than hydro alone, and wind generation will generally be higher in the winter period than in the summer. Wind will replace the generation with the highest operating cost, and reduce the average Nord Pool spot market price. 20 TWh wind will reduce price with about 3 oere/kWh and CO 2 emissions by 12-14 million tons for the case of replacing coal, and about 6 million tons for replacing natural gas. Wind impact on need for balancing power is small, i.e. the extra balancing cost is about 0,8 oere per kWh wind, and about half if investment in new reserve capacity is not needed. In summary this report demonstrates options for large scale integration

  18. In Situ Remediation Integrated Program: FY 1994 program summary

    International Nuclear Information System (INIS)

    1995-04-01

    The US Department of Energy (DOE) established the Office of Technology Development (EM-50) as an element of the Office of Environmental Management (EM) in November 1989. In an effort to focus resources and address priority needs, EM-50 introduced the concept of integrated programs (IPs) and integrated demonstrations (IDs). The In Situ Remediation Integrated Program (ISR IP) focuses research and development on the in-place treatment of contaminated environmental media, such as soil and groundwater, and the containment of contaminants to prevent the contaminants from spreading through the environment. Using in situ remediation technologies to clean up DOE sites minimizes adverse health effects on workers and the public by reducing contact exposure. The technologies also reduce cleanup costs by orders of magnitude. This report summarizes project work conducted in FY 1994 under the ISR IP in three major areas: treatment (bioremediation), treatment (physical/chemical), and containment technologies. Buried waste, contaminated soils and groundwater, and containerized waste are all candidates for in situ remediation. Contaminants include radioactive waste, volatile and nonvolatile organics, heavy metals, nitrates, and explosive materials

  19. In Situ Remediation Integrated Program: FY 1994 program summary

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    The US Department of Energy (DOE) established the Office of Technology Development (EM-50) as an element of the Office of Environmental Management (EM) in November 1989. In an effort to focus resources and address priority needs, EM-50 introduced the concept of integrated programs (IPs) and integrated demonstrations (IDs). The In Situ Remediation Integrated Program (ISR IP) focuses research and development on the in-place treatment of contaminated environmental media, such as soil and groundwater, and the containment of contaminants to prevent the contaminants from spreading through the environment. Using in situ remediation technologies to clean up DOE sites minimizes adverse health effects on workers and the public by reducing contact exposure. The technologies also reduce cleanup costs by orders of magnitude. This report summarizes project work conducted in FY 1994 under the ISR IP in three major areas: treatment (bioremediation), treatment (physical/chemical), and containment technologies. Buried waste, contaminated soils and groundwater, and containerized waste are all candidates for in situ remediation. Contaminants include radioactive waste, volatile and nonvolatile organics, heavy metals, nitrates, and explosive materials.

  20. Novel characteristics of CtIP at damage-induced foci following the initiation of DNA end resection

    International Nuclear Information System (INIS)

    Fujisawa, Hiroshi; Fujimori, Akira; Okayasu, Ryuichi; Uesaka, Mitsuru; Yajima, Hirohiko

    2015-01-01

    Highlights: • CtIP becomes hyperphosphorylated and forms foci following cell irradiation. • CtIP accumulates in foci subsequent to the peak of hyperphosphorylation. • CtIP is maintained in a hypophosphorylated state at later times. • CtIP is continuously recruited to DNA double strand breaks downstream of resection. • CtIP presumably have a distinct role following the initiation of resection. - Abstract: Homologous recombination (HR) is a major repair pathway for DNA double strand breaks (DSBs), and end resection, which generates a 3′-single strand DNA tail at the DSB, is an early step in the process. Resection is initiated by the Mre11 nuclease together with CtIP. Here, we describe novel characteristics of CtIP at DSBs. At early times following exposure of human cells to ionizing radiation, CtIP localized to the DSB, became hyperphosphorylated and formed foci in an ATM-dependent manner. At later times, when the initiation of resection had occurred, CtIP foci persist but CtIP is maintained in a hypophosphorylated state, which is dependent on ATM and ATR. Exposure to cycloheximide revealed that CtIP turns over at DSB sites downstream of resection. Our findings provide strong evidence that CtIP is continuously recruited to DSBs downstream of both the initiation and extension step of resection, strongly suggesting that CtIP has functions in addition to promoting the initiation of resection during HR