WorldWideScience

Sample records for innovative tools advance

  1. Drive Cost Reduction, Increase Innovation and Mitigate Risk with Advanced Knowledge Discovery Tools Designed to Unlock and Leverage Prior Knowledge

    International Nuclear Information System (INIS)

    Mitchell, I.

    2016-01-01

    Full text: The nuclear industry is knowledge-intensive and includes a diverse number of stakeholders. Much of this knowledge is at risk as engineers, technicians and project professionals retire, leaving a widening skills and information gap. This knowledge is critical in an increasingly complex environment with information from past projects often buried in decades-old, non-integrated systems enterprise. Engineers can spend 40% or more of their time searching for answers across the enterprise instead of solving problems. The inability to access trusted industry knowledge results in increased risk and expense. Advanced knowledge discovery technologies slash research times by as much as 75% and accelerate innovation and problem solving by giving technical professionals access to the information they need, in the context of the problems they are trying to solve. Unlike traditional knowledge management approaches, knowledge discovery tools powered by semantic search technologies are adept at uncovering answers in unstructured data and require no tagging, organization or moving of data, meaning a smaller IT footprint and faster time-to-knowledge. This session will highlight best-in-class knowledge discovery technologies, content, and strategies to give nuclear industry organizations the ability to leverage the corpus of enterprise knowledge into the future. (author

  2. Webinar as the innovative marketing tool: its place and a role in system of advancement of educational services

    Directory of Open Access Journals (Sweden)

    Matuhina Tatiana Vasilevna

    2011-04-01

    Full Text Available Marketing of webinar represents research which is carried out by seminar carrying out in a network the Internet, by means of virtual conference. Webinar as the innovative marketing tool allows the buyer to investigate a product or service, and to the supplier to investigate requirements and interests of the consumers by means of decrease in expenses for marketing since the technology of webinar-marketing is much more economic traditional than means of marketing, advertising, polls, seminars and conferences.

  3. Bridging Innovation and Outreach to Overcome Global Gaps in Radiation Oncology Through Information and Communication Tools, Trainee Advancement, Engaging Industry, Attention to Ethical Challenges, and Political Advocacy.

    Science.gov (United States)

    Dad, Luqman; Royce, Trevor J; Morris, Zachary; Moran, Meena; Pawlicki, Todd; Khuntia, Deepak; Hardenbergh, Patricia; Cummings, Bernard; Mayr, Nina; Hu, Kenneth

    2017-04-01

    An evolving paradigm in global outreach in radiation oncology has been the implementation of a more region-specific, needs-based approach to help close the gap in radiation services to low- and middle-income countries through the use of innovative tools in information and communication technology. This report highlights 4 information and communication technology tools in action today: (1) the NCCN Framework for Resource Stratification of NCCN guidelines, (2) ASTRO e-Contouring, (3) i.treatsafely.org, and (4) ChartRounds.com. We also render special consideration to matters related to global outreach that we believe require distinct attention to help us meet the goals established by the 2011 United Nations׳ Declaration on noncommunicable diseases: (1) trainee advancement toward careers in global health, (2) ethical challenges of international outreach, (3) critical importance of political advocacy, and (4) collaboration with Industry. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. INNOVATION MANAGEMENT TOOLS IN PUBLISHING COMPANIES

    Directory of Open Access Journals (Sweden)

    A. Shegda

    2013-09-01

    Full Text Available This article is devoted to the highly topical issue of modern publishing business as innovation management. introduction of technological innovation, measured as a promising strategy for the development of a constructive industry. The paper deals with main problems in managing of publishing companies. The reference consider of innovation management tools. In the article are exams the problems of books trend decline which require publishers introducing innovative methods of production and distribution. It was found that while the tools can be used. The process of innovation management with the following basic tools like as marketing innovation bench marketing, franchising, engineering innovation. It was found that while the tools can be used. So, the aim of the article is to analyze the modern tools of innovation management in the publishing field.

  5. Innovative Instructional Tools from the AMS

    Science.gov (United States)

    Abshire, W. E.; Geer, I. W.; Mills, E. W.; Nugnes, K. A.; Stimach, A. E.

    2016-12-01

    Since 1996, the American Meteorological Society (AMS) has been developing online educational materials with dynamic features that engage students and encourage additional exploration of various concepts. Most recently, AMS transitioned its etextbooks to webBooks. Now accessible anywhere with internet access, webBooks can be read with any web browser. Prior versions of AMS etextbooks were difficult to use in a lab setting, however webBooks are much easier to use and no longer a hurdle to learning. Additionally, AMS eInvestigations Manuals, also in webBook format, include labs with innovative features and educational tools. One such example is the AMS Climate at a Glance (CAG) app that draws data from NOAA's Climate at a Glance website. The user selects historical data of a given parameter and the app calculates various statistics revealing whether or not the results are consistent with climate change. These results allow users to distinguish between climate variability and climate change. This can be done for hundreds of locations across the U.S. and on multiple time scales. Another innovative educational tool used in AMS eInvestigations Manuals is the AMS Conceptual Climate Energy Model (CCEM). The CCEM is a computer simulation designed to enable users to track the paths that units of energy might follow as they enter, move through and exit an imaginary system according to simple rules applied to different scenarios. The purpose is to provide insight into the impacts of physical processes that operate in the real world. Finally, AMS educational materials take advantage of Google Earth imagery to reproduce the physical aspects of globes, allowing users to investigate spatial relationships in three dimensions. Google Earth imagery is used to explore tides, ocean bottom bathymetry and El Nino and La Nina. AMS will continue to develop innovative educational materials and tools as technology advances, to attract more students to the Earth sciences.

  6. Open Innovation at NASA: A New Business Model for Advancing Human Health and Performance Innovations

    Science.gov (United States)

    Davis, Jeffrey R.; Richard, Elizabeth E.; Keeton, Kathryn E.

    2014-01-01

    This paper describes a new business model for advancing NASA human health and performance innovations and demonstrates how open innovation shaped its development. A 45 percent research and technology development budget reduction drove formulation of a strategic plan grounded in collaboration. We describe the strategy execution, including adoption and results of open innovation initiatives, the challenges of cultural change, and the development of virtual centers and a knowledge management tool to educate and engage the workforce and promote cultural change.

  7. Towards multidisciplinary support tools for innovation tasks

    NARCIS (Netherlands)

    Wits, Wessel Willems; Bakker, H.M.; Chechurin, L.S.

    2012-01-01

    This paper highlights the imperative need for innovation and characterizes a promising support tool to stimulate this process. The importance of innovation for both a global economy and specifically for engineering education is discussed. Additionally, the urgency for multidisciplinary skills for

  8. Advanced Prosthetic Gait Training Tool

    Science.gov (United States)

    2015-12-01

    modules to train individuals to distinguish gait deviations (trunk motion and lower-limb motion). Each of these modules help trainers improve their...AWARD NUMBER: W81XWH-10-1-0870 TITLE: Advanced Prosthetic Gait Training Tool PRINCIPAL INVESTIGATOR: Dr. Karim Abdel-Malek CONTRACTING...study is to produce a computer-based Advanced Prosthetic Gait Training Tool to aid in the training of clinicians at military treatment facilities

  9. ANT Advanced Neural Tool

    Energy Technology Data Exchange (ETDEWEB)

    Labrador, I.; Carrasco, R.; Martinez, L.

    1996-07-01

    This paper describes a practical introduction to the use of Artificial Neural Networks. Artificial Neural Nets are often used as an alternative to the traditional symbolic manipulation and first order logic used in Artificial Intelligence, due the high degree of difficulty to solve problems that can not be handled by programmers using algorithmic strategies. As a particular case of Neural Net a Multilayer Perception developed by programming in C language on OS9 real time operating system is presented. A detailed description about the program structure and practical use are included. Finally, several application examples that have been treated with the tool are presented, and some suggestions about hardware implementations. (Author) 15 refs.

  10. ANT Advanced Neural Tool

    International Nuclear Information System (INIS)

    Labrador, I.; Carrasco, R.; Martinez, L.

    1996-01-01

    This paper describes a practical introduction to the use of Artificial Neural Networks. Artificial Neural Nets are often used as an alternative to the traditional symbolic manipulation and first order logic used in Artificial Intelligence, due the high degree of difficulty to solve problems that can not be handled by programmers using algorithmic strategies. As a particular case of Neural Net a Multilayer Perception developed by programming in C language on OS9 real time operating system is presented. A detailed description about the program structure and practical use are included. Finally, several application examples that have been treated with the tool are presented, and some suggestions about hardware implementations. (Author) 15 refs

  11. The NRNU MEPhI activities in the development and applications of advanced tools for innovative nuclear energy systems sustainability assessments - 5020

    International Nuclear Information System (INIS)

    Andrianov, A.; Dogov, A.; Kuptsov, I.; Fedorova, E.; Svetlichnyy, L.; Utianskaia, T.; Korovin, Y.

    2015-01-01

    This report delineates the multi-objective optimization and uncertainty treatment modules for the IAEA energy planning software MESSAGE developed at the National Research Nuclear University MEPhI and the Obninsk Institute for Nuclear Power Engineering intended for multi-objective optimization and sustainability assessments of innovative nuclear energy systems with account of uncertainty. The authors present some results of implementation of these tools for multi-objective nuclear energy system optimization studies. The developed software allows searching for compromises between the conflicting factors that determine the nuclear energy systems' effectiveness and calculating corresponding trade-off rates; carrying out comparative multi-criteria analysis of alternatives as well as choosing, ranking, and sorting corresponding options taking into account the evolution dynamics, structure and organization of a nuclear fuel cycle and the most important system constraints and restrictions. (authors)

  12. Advanced real-time multi-display educational system (ARMES): An innovative real-time audiovisual mentoring tool for complex robotic surgery.

    Science.gov (United States)

    Lee, Joong Ho; Tanaka, Eiji; Woo, Yanghee; Ali, Güner; Son, Taeil; Kim, Hyoung-Il; Hyung, Woo Jin

    2017-12-01

    The recent scientific and technologic advances have profoundly affected the training of surgeons worldwide. We describe a novel intraoperative real-time training module, the Advanced Robotic Multi-display Educational System (ARMES). We created a real-time training module, which can provide a standardized step by step guidance to robotic distal subtotal gastrectomy with D2 lymphadenectomy procedures, ARMES. The short video clips of 20 key steps in the standardized procedure for robotic gastrectomy were created and integrated with TilePro™ software to delivery on da Vinci Surgical Systems (Intuitive Surgical, Sunnyvale, CA). We successfully performed the robotic distal subtotal gastrectomy with D2 lymphadenectomy for patient with gastric cancer employing this new teaching method without any transfer errors or system failures. Using this technique, the total operative time was 197 min and blood loss was 50 mL and there were no intra- or post-operative complications. Our innovative real-time mentoring module, ARMES, enables standardized, systematic guidance during surgical procedures. © 2017 Wiley Periodicals, Inc.

  13. Innovative algorithms and tools summary and outlook

    International Nuclear Information System (INIS)

    Fine, V.E.; Naumann, N.A.

    2003-01-01

    This contribution provides a summary of the 'Session IV: Innovative Algorithms and Tools'. The 'tools' portion of the session IV comprised three oral sessions, 12 talks by seven speakers, and three posters. The algorithmic part was covered by 15 talks and three poster presentations. We will try to give a summary of the main development directions, and state our personal views and interpretation on it as well as an outlook

  14. Innovative Tools to Assess Systems Thinking Ability

    Science.gov (United States)

    2017-12-01

    addition to the six cognitive ability constructs, there are two motivational attributes that are highly relevant to systems thinking performance...roles of the habenular complex, the reward system , and the cingulate motor area revealed by functional magnetic resonance imaging. Journal of...Technical Report 1362 Innovative Tools to Assess Systems Thinking Ability Cory Adis Michelle Wisecarver Chelsey Raber Personnel

  15. International Conference on Advanced Computing for Innovation

    CERN Document Server

    Angelova, Galia; Agre, Gennady

    2016-01-01

    This volume is a selected collection of papers presented and discussed at the International Conference “Advanced Computing for Innovation (AComIn 2015)”. The Conference was held at 10th -11th of November, 2015 in Sofia, Bulgaria and was aimed at providing a forum for international scientific exchange between Central/Eastern Europe and the rest of the world on several fundamental topics of computational intelligence. The papers report innovative approaches and solutions in hot topics of computational intelligence – advanced computing, language and semantic technologies, signal and image processing, as well as optimization and intelligent control.

  16. Young children's tool innovation across culture: Affordance visibility matters.

    Science.gov (United States)

    Neldner, Karri; Mushin, Ilana; Nielsen, Mark

    2017-11-01

    Young children typically demonstrate low rates of tool innovation. However, previous studies have limited children's performance by presenting tools with opaque affordances. In an attempt to scaffold children's understanding of what constitutes an appropriate tool within an innovation task we compared tools in which the focal affordance was visible to those in which it was opaque. To evaluate possible cultural specificity, data collection was undertaken in a Western urban population and a remote Indigenous community. As expected affordance visibility altered innovation rates: young children were more likely to innovate on a tool that had visible affordances than one with concealed affordances. Furthermore, innovation rates were higher than those reported in previous innovation studies. Cultural background did not affect children's rates of tool innovation. It is suggested that new methods for testing tool innovation in children must be developed in order to broaden our knowledge of young children's tool innovation capabilities. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Advanced SOA tools and applications

    CERN Document Server

    Brzezinski, Jerzy; Cellary, Wojciech; Grzech, Adam; Zielinski, Krzysztof

    2014-01-01

    This book presents advanced software development tools for construction, deployment and governance of Service Oriented Architecture (SOA) applications. Novel technical concepts and paradigms, formulated during the research stage and during development of such tools are presented and illustrated by practical usage examples. Hence this book will be of interest not only to theoreticians but also to engineers who cope with real-life problems. Additionally, each chapter contains an overview of related work, enabling comparison of the proposed concepts with exiting solutions in various areas of the SOA development process. This makes the book interesting also for students and scientists who investigate similar issues.

  18. Advanced pressure tube sampling tools

    International Nuclear Information System (INIS)

    Wittich, K.C.; King, J.M.

    2002-01-01

    Deuterium concentration is an important parameter that must be assessed to evaluate the Fitness for service of CANDU pressure tubes. In-reactor pressure tube sampling allows accurate deuterium concentration assessment to be made without the expenses associated with fuel channel removal. This technology, which AECL has developed over the past fifteen years, has become the standard method for deuterium concentration assessment. AECL is developing a multi-head tool that would reduce in-reactor handling overhead by allowing one tool to sequentially sample at all four axial pressure tube locations before removal from the reactor. Four sets of independent cutting heads, like those on the existing sampling tools, facilitate this incorporating proven technology demonstrated in over 1400 in-reactor samples taken to date. The multi-head tool is delivered by AECL's Advanced Delivery Machine or other similar delivery machines. Further, AECL has developed an automated sample handling system that receives and processes the tool once out of the reactor. This system retrieves samples from the tool, dries, weighs and places them in labelled vials which are then directed into shielded shipping flasks. The multi-head wet sampling tool and the automated sample handling system are based on proven technology and offer continued savings and dose reduction to utilities in a competitive electricity market. (author)

  19. Designing an ICT tool platform to support SME business model innovation: Results of a first design cycle

    NARCIS (Netherlands)

    de Reuver, G.A.; Athanasopoulou, A.; Haaker, T.I.; Roelfsema, M.; Riedle, M; Breitfuss, G.

    2016-01-01

    Business model innovation (BMI) is becoming increasingly relevant for enterprises as they are faced with profound changes like digitalization. While business model thinking in academia has advanced, practical tooling that supports business model innovation for small and medium sized enterprises

  20. TOOLS FOR COLLABORATION AND INNOVATION IN SMES

    Directory of Open Access Journals (Sweden)

    Joe ENGLISH

    2014-11-01

    Full Text Available SMEs (small and medium-sized enterprises and micro-enterprises are the backbone of the EU economy. Their prosperity is a crucial factor for achieving more growth and more and better jobs in the EU. They are vital to fulfilling the goal of a more equal and productive society with higher social and economic integration. Yet they are often poorly equipped to fulfill their potential as innovators and entrepreneurs, especially in the relentless transition to a knowledge based society, both because of their diverse academic backgrounds and their lack of training. This paper summarizes work currently underway by two diverse teams across Europe to develop and roll out a suite of training and tools to enhance the innovation and collaboration capacities and capabilities of small and micro-businesses.

  1. CATEGORICAL TOOL OF INNOVATIVE LABOR PROVIDING IN MODERN CONDITIONS

    Directory of Open Access Journals (Sweden)

    Anna Chernoivanova

    2017-03-01

    Full Text Available The article aims to study theoretical foundations of providing innovative work in modern conditions based on systematizing categorical tools. As a result of the study we found out the innovative work features and singled it out among other related to it categories such as “creative work”, “intellectual work”, “labor management”; summarized theoretical propositions about the nature of innovation work and clarified its definition. Classification of innovative work was grounded. The features of the innovative work were defined. Innovative work was singled out among other related to it types of work. Keywords: innovative work, the types of innovative work, creative work.

  2. IMPLEMENTING A VALUE ASSESSMENT TOOL FOR SERVICE INNOVATION IDEAS

    OpenAIRE

    TOR HELGE AAS

    2010-01-01

    There has not been much discussion of how firms may assess the value of service innovation projects ex-ante in the extant research literature. This paper theoretically derives a value assessment tool for service innovation ideas called QSI (tool for pre-Qualification of Service Innovation projects). Thereafter QSI is implemented in three firms and it is explored to what degree the implementation improved managerial decision making on service innovation projects and investments. The findings i...

  3. Advanced design cultures long-term perspective and continuous innovation

    CERN Document Server

    2015-01-01

    This book describes new thinking and practice in Advanced Design (ADD) – design that is not merely highly developed but anticipates the future by envisioning novel products and processes. The focus is especially on the front end of innovation and the search for solutions in complex pioneering processes using design-related tools and practices. The book opens by describing these tools, the approaches that characterize ADD, and its historical dimension. Specific fields in which ADD has flourished are then examined, exploring the dynamics between research and design. The coverage ranges from transportation, lighting, and electrical appliances through to business networks, technology parks, and the development of ground-breaking materials. AdvanceDesign is the name of the research group at the Politecnico di Milano (Italy’s largest technical university) of which the authors are members. It was chosen to reflect both the “advanced”, tangible dimension of design in terms of modern product development, mater...

  4. Finland: Innovation Policy Tools under National Innovation System Crisis

    Directory of Open Access Journals (Sweden)

    Daria A. Vorobeva

    2017-01-01

    Full Text Available Purpose: the for a long time Finland’s national innovation system (NIS had been being one of the most successful and effective in the world. But some years ago the situation changed: Finland’s NIS run into system crisis. And today Finnish government tries to work out anticrisis innovation policy. So the purpose of this article is to show up the innovation policy instruments which are able put an end to the crisis and to determine conditions of their successful use. Methods: the article is based on the national innovation systems concept and government policy-mix aimed at the NIS development. Results: the authors show up how Finnish government looks for optimal policy-mix to overcome the crisis, demonstrate in details complementary components of the relevant innovation policy, describe conditions for their success and effectiveness to consider whether they are useful in other countries. Conclusions and Relevance: to overcome the NIS crisis the Finnish government uses such instruments as strategic programs of socio-economic development with targets which can’t be achieved without adequate high technology and innovative development complemented by incentives to make business innovate actively. The conditions of such policy success are: 1 such feature of Finnish society as all stakeholders of economic development consensus on one issue: the main factor of development are innovations; 2 anticrisis stage of Finnish innovative policy is based previously accumulated knowledge and know-how. 

  5. ADVANCED POWER SYSTEMS ANALYSIS TOOLS

    Energy Technology Data Exchange (ETDEWEB)

    Robert R. Jensen; Steven A. Benson; Jason D. Laumb

    2001-08-31

    The use of Energy and Environmental Research Center (EERC) modeling tools and improved analytical methods has provided key information in optimizing advanced power system design and operating conditions for efficiency, producing minimal air pollutant emissions and utilizing a wide range of fossil fuel properties. This project was divided into four tasks: the demonstration of the ash transformation model, upgrading spreadsheet tools, enhancements to analytical capabilities using the scanning electron microscopy (SEM), and improvements to the slag viscosity model. The ash transformation model, Atran, was used to predict the size and composition of ash particles, which has a major impact on the fate of the combustion system. To optimize Atran key factors such as mineral fragmentation and coalescence, the heterogeneous and homogeneous interaction of the organically associated elements must be considered as they are applied to the operating conditions. The resulting model's ash composition compares favorably to measured results. Enhancements to existing EERC spreadsheet application included upgrading interactive spreadsheets to calculate the thermodynamic properties for fuels, reactants, products, and steam with Newton Raphson algorithms to perform calculations on mass, energy, and elemental balances, isentropic expansion of steam, and gasifier equilibrium conditions. Derivative calculations can be performed to estimate fuel heating values, adiabatic flame temperatures, emission factors, comparative fuel costs, and per-unit carbon taxes from fuel analyses. Using state-of-the-art computer-controlled scanning electron microscopes and associated microanalysis systems, a method to determine viscosity using the incorporation of grey-scale binning acquired by the SEM image was developed. The image analysis capabilities of a backscattered electron image can be subdivided into various grey-scale ranges that can be analyzed separately. Since the grey scale's intensity

  6. CATEGORICAL TOOL OF INNOVATIVE LABOR PROVIDING IN MODERN CONDITIONS

    OpenAIRE

    Chernoivanova, Anna

    2017-01-01

    The article aims to study theoretical foundations of providing innovative work in modern conditions based on systematizing categorical tools. As a result of the study we found out the innovative work features and singled it out among other related to it categories such as “creative work”, “intellectual work”, “labor management”; summarized theoretical propositions about the nature of innovation work and clarified its definition. Classification of innovative work was grounded. The features of ...

  7. High Performance Grinding and Advanced Cutting Tools

    CERN Document Server

    Jackson, Mark J

    2013-01-01

    High Performance Grinding and Advanced Cutting Tools discusses the fundamentals and advances in high performance grinding processes, and provides a complete overview of newly-developing areas in the field. Topics covered are grinding tool formulation and structure, grinding wheel design and conditioning and applications using high performance grinding wheels. Also included are heat treatment strategies for grinding tools, using grinding tools for high speed applications, laser-based and diamond dressing techniques, high-efficiency deep grinding, VIPER grinding, and new grinding wheels.

  8. Advancing innovation in health care leadership: a collaborative experience.

    Science.gov (United States)

    Garcia, Victor H; Meek, Kevin L; Wilson, Kimburli A

    2011-01-01

    The changing framework of today's health care system requires leaders to be increasingly innovative in how they approach their daily functions and responsibilities. Sustaining and advancing a level of innovation that already exists can be challenging for health care administrators with the demands of time and resource limitations. Using collaboration to bring new-age teaching and disciplines to front-line leadership, one hospital was able to reinvigorate a culture of innovation through multiple levels and disciplines of the organization. The Innovation Certification Course provided nursing leaders and other managers' an evidence-drive approach, new principles and useful strategies of innovative leadership and graduate program education.

  9. Innovative tool for specifying customer requirements

    NARCIS (Netherlands)

    Ellman, A.; Wendrich, Robert E.; Tiainen, T.

    2014-01-01

    This paper presents the design and development of an App based tool for specification of customer requirements (CR) for product development. The most Quality Function Deployment (QFD) tools and methods are system based or used as an Excel document for specification and evaluation. Nowadays tool

  10. Innovative Software Algorithms and Tools parallel sessions summary

    International Nuclear Information System (INIS)

    Gaines, Irwin

    2001-01-01

    A variety of results were presented in the poster and 5 parallel sessions of the Innovative Software, Algorithms and Tools (ISAT) sessions. I will briefly summarize these presentations and attempt to identify some unifying trends

  11. Modern tools in the management of competitiveness of innovative entrepreneurship

    Directory of Open Access Journals (Sweden)

    K. Reshetov

    2015-01-01

    Full Text Available The purpose of this paper is to study the role of planning and forecasting in management of economic systems, including the management of innovative business structures. Methods. Methodological basis of this paper is generalization of literary sources.Results. The article shows the importance and feasibility of using modern tools in the management of competitiveness of innovative entrepreneurship, in particular the need to apply foresight design and road mapping. This article substantiates the practical necessity of using modern innovative business structures in order to achieve high competitiveness planning tools and forecasting of its activities (and in particular, foresight design and road mapping.

  12. PII- Potential Innovation Index: a Tool to Benchmark Innovation Capabilities in International Context

    Directory of Open Access Journals (Sweden)

    Daniel Galvez

    2013-12-01

    Full Text Available Benchmarking has become a useful tool for companies, enabling better decision-making and improvement of internal practices towards world-class performance. Nevertheless, concerning SMEs’ innovation capabilities from traditional sectors, benchmarking applications have been scarce. This article uses a predefined metric named the “Potential Innovation Index (PII”, based on internal practices of the firms to compare innovation capabilities of two groups of similar SMEs from 2 different geographical, cultural and social contexts. Results were used to analyze similarities and differences, strengths and weaknesses of the groups. Obtained results confirm the difficulties to innovate of this type firms, no matters the sector or country, as over 55% of the companies studied were evaluated as having a low innovative performance. However, regarding the index’s constitutive practices, significant differences were found. Which leads to infer that innovation support strategies to enhance innovation must be adapted to the local context and culture.

  13. Innovative voucher as a prospect tool for grant funding

    Directory of Open Access Journals (Sweden)

    V. A. Barinova

    2015-01-01

    Full Text Available The article aims to explore innovative international practice for advancing the mechanisms of distributing grant funding. Authors analyze a practical case study of successful implementation of innovative vouchers overseas, and draw parallels with regard to already formed institutes in Russia, corresponding with foreign in terms of their functional. Possible mechanisms for implementing successful foreign practices of utilizing innovative vouchers in Russia were studied in this article. On the basis of conducted analysis authors evaluate perspectives of implementing the suggested scheme in Russia.

  14. Brains, tools, innovation and biogeography in crows and ravens

    Science.gov (United States)

    2012-01-01

    Background Crows and ravens (Passeriformes: Corvus) are large-brained birds with enhanced cognitive abilities relative to other birds. They are among the few non-hominid organisms on Earth to be considered intelligent and well-known examples exist of several crow species having evolved innovative strategies and even use of tools in their search for food. The 40 Corvus species have also been successful dispersers and are distributed on most continents and in remote archipelagos. Results This study presents the first molecular phylogeny including all species and a number of subspecies within the genus Corvus. We date the phylogeny and determine ancestral areas to investigate historical biogeographical patterns of the crows. Additionally, we use data on brain size and a large database on innovative behaviour and tool use to test whether brain size (i) explains innovative behaviour and success in applying tools when foraging and (ii) has some correlative role in the success of colonization of islands. Our results demonstrate that crows originated in the Palaearctic in the Miocene from where they dispersed to North America and the Caribbean, Africa and Australasia. We find that relative brain size alone does not explain tool use, innovative feeding strategies and dispersal success within crows. Conclusions Our study supports monophyly of the genus Corvus and further demonstrates the direction and timing of colonization from the area of origin in the Palaearctic to other continents and archipelagos. The Caribbean was probably colonized from North America, although some North American ancestor may have gone extinct, and the Pacific was colonized multiple times from Asia and Australia. We did not find a correlation between relative brain size, tool use, innovative feeding strategies and dispersal success. Hence, we propose that all crows and ravens have relatively large brains compared to other birds and thus the potential to be innovative if conditions and circumstances

  15. Editoral Comment: Innovation as a Multidimensional Solution Tool to ...

    African Journals Online (AJOL)

    International Journal of Basic, Applied and Innovative Research. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 3, No 1 (2014) >. Log in or Register to get access to full text downloads.

  16. Stream analysis, a practical tool for innovators and change agents

    NARCIS (Netherlands)

    Kastelein, A.

    1993-01-01

    To survive organizations have to innovate and to change. Fundamental questions are: * Which strategies and tools could be applied succesfully in the everchanging environment? * Are the identified instruments effective iri our business? * Do we need professional support? In more than a dozen projects

  17. Brains, tools, innovation and biogeography in crows and ravens

    DEFF Research Database (Denmark)

    Jønsson, Knud Andreas; Fabre, Pierre-Henri Fréderic; Irestedt, Martin

    2012-01-01

    BACKGROUND:Crows and ravens (Passeriformes: Corvus) are large-brained birds with enhanced cognitive abilities relative to other birds. They are among the few non-hominid organisms on Earth to be considered intelligent and well-known examples exist of several crow species having evolved innovative....... Hence, we propose that all crows and ravens have relatively large brains compared to other birds and thus the potential to be innovative if conditions and circumstances are right.......BACKGROUND:Crows and ravens (Passeriformes: Corvus) are large-brained birds with enhanced cognitive abilities relative to other birds. They are among the few non-hominid organisms on Earth to be considered intelligent and well-known examples exist of several crow species having evolved innovative...... Corvus. We date the phylogeny and determine ancestral areas to investigate historical biogeographical patterns of the crows. Additionally, we use data on brain size and a large database on innovative behaviour and tool use to test whether brain size (i) explains innovative behaviour and success...

  18. European regulatory tools for advanced therapy medicinal products.

    Science.gov (United States)

    Flory, Egbert; Reinhardt, Jens

    2013-12-01

    Increasing scientific knowledge and technical innovations in the areas of cell biology, biotechnology and medicine resulted in the development of promising therapeutic approaches for the prevention and treatment of human diseases. Advanced therapy medicinal products (ATMPs) reflect a complex and innovative class of biopharmaceuticals as these products are highly research-driven, characterised by innovative manufacturing processes and heterogeneous with regard to their origin, type and complexity. This class of ATMP integrates gene therapy medicinal products, somatic cell therapy medicinal products and tissue engineering products and are often individualized and patient-specific products. Multiple challenges arise from the nature of ATMPs, which are often developed by micro, small and medium sized enterprises, university and academia, for whom regulatory experiences are limited and regulatory requirements are challenging. Regulatory guidance such as the reflection paper on classification of ATMPs and guidelines highlighting product-specific issues support academic research groups and pharmaceutical companies to foster the development of safe and effective ATMPs. This review provides an overview on the European regulatory aspects of ATMPs and highlights specific regulatory tools such as the ATMP classification procedure, a discussion on the hospital exemption for selected ATMPs as well as borderline issues towards transplants/transfusion products.

  19. Innovations in Advanced Materials and Metals Manufacturing Project (IAM2)

    Energy Technology Data Exchange (ETDEWEB)

    Scott, Elizabeth [Columbia River Economic Development Council, Vancouver, WA (United States)

    2017-01-06

    This project, under the Jobs and Innovation Accelerator Challenge, Innovations in Advanced Materials and Metals Manufacturing Project, contracted with Cascade Energy to provide a shared energy project manager engineer to work with five different companies throughout the Portland metro grant region to implement ten energy efficiency projects and develop a case study to analyze the project model. As a part of the project, the energy project manager also looked into specific new technologies and methodologies that could change the way energy is consumed by manufacturers—from game-changing equipment and technology to monitor energy use to methodologies that change the way companies interact and use their machines to reduce energy consumption.

  20. 76 FR 23543 - The Jobs and Innovation Accelerator Challenge; a Coordinated Initiative To Advance Regional...

    Science.gov (United States)

    2011-04-27

    ... Jobs and Innovation Accelerator Challenge; a Coordinated Initiative To Advance Regional Competitiveness... Federal resources to support regional innovation and sustainable economic prosperity. Knowing that regional innovation clusters provide a globally proven approach for developing economic prosperity, this...

  1. Advanced free-form micro tooling

    DEFF Research Database (Denmark)

    Tosello, Guido; Gavillet, J.

    2011-01-01

    -beam lithography and nano imprinting lithography [Che05][Che09] have high manufacturing cost and a low throughput. The aim was obtain large tool area with nano structures patterning without using energy intensive nano machining (e.g. focus ion beam, X-ray lithography, etc) but, instead, by exploiting the advantage......The present deliverable contains the report of the work and results achieved within the framework of WP 2.2 in Tasks 2.2.4 “Advanced free-form micro tooling” in experimental research done regarding practical applications of methods of applying nano structures to tooling solutions. As part of Task 2.......2.4, tests based on three different chemical-based-batch techniques to establish surface nano (i.e. sub-μm) structures on large tools area were performed. The three approached regarded: o Scheme 1  The use of Ø500nm nanobeads deposition for direct patterning of a Ø4inch. silicon wafer and subsequent nickel...

  2. Diamond turning on advanced machine tool prototypes

    International Nuclear Information System (INIS)

    Arnold, J.B.; Steger, P.J.

    1975-01-01

    Specular-quality metal mirrors are being machined for use in laser optical systems. The fabrication process incorporates special quality diamond tools and specially constructed turning machines. The machines are controlled by advanced control techniques and are housed in an environmentally controlled laboratory to insure ultimate machine stability and positional accuracy. The materials from which these mirrors are primarily produced are the softer face-center-cubic structure metals, such as gold, silver, copper, and aluminum. Mirror manufacturing by the single-point diamond machining process is in an early stage of development, but it is anticipated that this method will become the most economical way for producing high-quality metal mirrors. (U.S.)

  3. Conceptual assessment tool for advanced undergraduate electrodynamics

    Science.gov (United States)

    Baily, Charles; Ryan, Qing X.; Astolfi, Cecilia; Pollock, Steven J.

    2017-12-01

    As part of ongoing investigations into student learning in advanced undergraduate courses, we have developed a conceptual assessment tool for upper-division electrodynamics (E&M II): the Colorado UppeR-division ElectrodyNamics Test (CURrENT). This is a free response, postinstruction diagnostic with 6 multipart questions, an optional 3-question preinstruction test, and accompanying grading rubrics. The instrument's development was guided by faculty-consensus learning goals and research into common student difficulties. It can be used to gauge the effectiveness of transformed pedagogy, and to gain insights into student thinking in the covered topic areas. We present baseline data representing 500 students across 9 institutions, along with validity, reliability, and discrimination measures of the instrument and scoring rubric.

  4. Conceptual assessment tool for advanced undergraduate electrodynamics

    Directory of Open Access Journals (Sweden)

    Charles Baily

    2017-09-01

    Full Text Available As part of ongoing investigations into student learning in advanced undergraduate courses, we have developed a conceptual assessment tool for upper-division electrodynamics (E&M II: the Colorado UppeR-division ElectrodyNamics Test (CURrENT. This is a free response, postinstruction diagnostic with 6 multipart questions, an optional 3-question preinstruction test, and accompanying grading rubrics. The instrument’s development was guided by faculty-consensus learning goals and research into common student difficulties. It can be used to gauge the effectiveness of transformed pedagogy, and to gain insights into student thinking in the covered topic areas. We present baseline data representing 500 students across 9 institutions, along with validity, reliability, and discrimination measures of the instrument and scoring rubric.

  5. Creating a new innovation practice and a different innovation orientation through implementation of an idea competition tool

    DEFF Research Database (Denmark)

    Nicolajsen, Hanne Westh; Scupola, Ada

    2012-01-01

    We investigate how an idea competition tool act as catalyst to create a new innovation practice and innovation orientation in an engineering consultancy company. The idea competition is used internally in the organization to collect employee ideas for internal process improvements. The case study...... barriers by creating a strategic business architecture encouraging employees to contribute with innovative ideas that the company may develop and implement for the good of the company. The findings indicate that more and different innovation orientations may co-exist in the same organization, complementing...... each other, such as balancing an external customer orientation with an innovation orientation focusing on internal innovations....

  6. Public procurement as a tool to drive innovation in South Africa ...

    African Journals Online (AJOL)

    This article is an analysis of the use of public procurement as a tool to drive innovation. It explores the meaning of innovative procurement or public procurement of innovation, as well as the rationale for using public procurement to drive innovation. It then focuses on South Africa and evaluates whether there is scope within ...

  7. Innovations and Advances in Computer, Information, Systems Sciences, and Engineering

    CERN Document Server

    Sobh, Tarek

    2013-01-01

    Innovations and Advances in Computer, Information, Systems Sciences, and Engineering includes the proceedings of the International Joint Conferences on Computer, Information, and Systems Sciences, and Engineering (CISSE 2011). The contents of this book are a set of rigorously reviewed, world-class manuscripts addressing and detailing state-of-the-art research projects in the areas of  Industrial Electronics, Technology and Automation, Telecommunications and Networking, Systems, Computing Sciences and Software Engineering, Engineering Education, Instructional Technology, Assessment, and E-learning.

  8. The development of tool manufacture in humans: what helps young children make innovative tools?

    Science.gov (United States)

    Chappell, Jackie; Cutting, Nicola; Apperly, Ian A; Beck, Sarah R

    2013-11-19

    We know that even young children are proficient tool users, but until recently, little was known about how they make tools. Here, we will explore the concepts underlying tool making, and the kinds of information and putative cognitive abilities required for children to manufacture novel tools. We will review the evidence for novel tool manufacture from the comparative literature and present a growing body of data from children suggesting that innovation of the solution to a problem by making a tool is a much more challenging task than previously thought. Children's difficulty with these kinds of tasks does not seem to be explained by perseveration with unmodified tools, difficulty with switching to alternative strategies, task pragmatics or issues with permission. Rather, making novel tools (without having seen an example of the required tool within the context of the task) appears to be hard, because it is an example of an 'ill-structured problem'. In this type of ill-structured problem, the starting conditions and end goal are known, but the transformations and/or actions required to get from one to the other are not specified. We will discuss the implications of these findings for understanding the development of problem-solving in humans and other animals.

  9. The development of tool manufacture in humans: what helps young children make innovative tools?

    Science.gov (United States)

    Chappell, Jackie; Cutting, Nicola; Apperly, Ian A.; Beck, Sarah R.

    2013-01-01

    We know that even young children are proficient tool users, but until recently, little was known about how they make tools. Here, we will explore the concepts underlying tool making, and the kinds of information and putative cognitive abilities required for children to manufacture novel tools. We will review the evidence for novel tool manufacture from the comparative literature and present a growing body of data from children suggesting that innovation of the solution to a problem by making a tool is a much more challenging task than previously thought. Children's difficulty with these kinds of tasks does not seem to be explained by perseveration with unmodified tools, difficulty with switching to alternative strategies, task pragmatics or issues with permission. Rather, making novel tools (without having seen an example of the required tool within the context of the task) appears to be hard, because it is an example of an ‘ill-structured problem’. In this type of ill-structured problem, the starting conditions and end goal are known, but the transformations and/or actions required to get from one to the other are not specified. We will discuss the implications of these findings for understanding the development of problem-solving in humans and other animals. PMID:24101620

  10. An innovative virtual reality training tool for orthognathic surgery.

    Science.gov (United States)

    Pulijala, Y; Ma, M; Pears, M; Peebles, D; Ayoub, A

    2018-02-01

    Virtual reality (VR) surgery using Oculus Rift and Leap Motion devices is a multi-sensory, holistic surgical training experience. A multimedia combination including 360° videos, three-dimensional interaction, and stereoscopic videos in VR has been developed to enable trainees to experience a realistic surgery environment. The innovation allows trainees to interact with the individual components of the maxillofacial anatomy and apply surgical instruments while watching close-up stereoscopic three-dimensional videos of the surgery. In this study, a novel training tool for Le Fort I osteotomy based on immersive virtual reality (iVR) was developed and validated. Seven consultant oral and maxillofacial surgeons evaluated the application for face and content validity. Using a structured assessment process, the surgeons commented on the content of the developed training tool, its realism and usability, and the applicability of VR surgery for orthognathic surgical training. The results confirmed the clinical applicability of VR for delivering training in orthognathic surgery. Modifications were suggested to improve the user experience and interactions with the surgical instruments. This training tool is ready for testing with surgical trainees. Copyright © 2018 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  11. Counterfactual Imagination as a Mental Tool for Innovation

    Directory of Open Access Journals (Sweden)

    Monika Chylińska

    2017-11-01

    Full Text Available In the article I demonstrate some of the possible ways by which counterfactual im⁠agination can lead people to innovation and the creation of novel and valuable solutions. I start with adopting the broad definition of counterfactuals, by which counterfactual imagination is understood as the ability to imagine alternative states of affairs which can relate to the past, present or future. I explain how counterfactual imagination differs from other sorts of imaginative and creative thoughts, pointing out that counterfactual types of thinking always rely on facts and involve a change in some features of the actual world, leaving other such features unaltered. I also show that the concept of counterfactual imagination can be useful when we aim to describe the very earliest manifestations of imaginative capacities in children, which can be seen in their make-believe games. All the mentioned characteristics of counterfactual imagination are further used to examine how what if and would be sorts of thinking and imagining might influence people’s creative performance. I conclude with the suggestion that—if guided properly—counterfactual imagination could be a truly valuable mental tool for innovation. This demonstration is partly influenced by Ruth Byrne’s multi-faceted analysis of counterfactual imagination, mainly from her book, The Rational Imagination: How People Create Alternatives to Reality.

  12. The EU-ADR Web Platform: delivering advanced pharmacovigilance tools.

    Science.gov (United States)

    Oliveira, José Luis; Lopes, Pedro; Nunes, Tiago; Campos, David; Boyer, Scott; Ahlberg, Ernst; van Mulligen, Erik M; Kors, Jan A; Singh, Bharat; Furlong, Laura I; Sanz, Ferran; Bauer-Mehren, Anna; Carrascosa, Maria C; Mestres, Jordi; Avillach, Paul; Diallo, Gayo; Díaz Acedo, Carlos; van der Lei, Johan

    2013-05-01

    Pharmacovigilance methods have advanced greatly during the last decades, making post-market drug assessment an essential drug evaluation component. These methods mainly rely on the use of spontaneous reporting systems and health information databases to collect expertise from huge amounts of real-world reports. The EU-ADR Web Platform was built to further facilitate accessing, monitoring and exploring these data, enabling an in-depth analysis of adverse drug reactions risks. The EU-ADR Web Platform exploits the wealth of data collected within a large-scale European initiative, the EU-ADR project. Millions of electronic health records, provided by national health agencies, are mined for specific drug events, which are correlated with literature, protein and pathway data, resulting in a rich drug-event dataset. Next, advanced distributed computing methods are tailored to coordinate the execution of data-mining and statistical analysis tasks. This permits obtaining a ranked drug-event list, removing spurious entries and highlighting relationships with high risk potential. The EU-ADR Web Platform is an open workspace for the integrated analysis of pharmacovigilance datasets. Using this software, researchers can access a variety of tools provided by distinct partners in a single centralized environment. Besides performing standalone drug-event assessments, they can also control the pipeline for an improved batch analysis of custom datasets. Drug-event pairs can be substantiated and statistically analysed within the platform's innovative working environment. A pioneering workspace that helps in explaining the biological path of adverse drug reactions was developed within the EU-ADR project consortium. This tool, targeted at the pharmacovigilance community, is available online at https://bioinformatics.ua.pt/euadr/. Copyright © 2012 John Wiley & Sons, Ltd.

  13. International conference on Advances in Intelligent Control and Innovative Computing

    CERN Document Server

    Castillo, Oscar; Huang, Xu; Intelligent Control and Innovative Computing

    2012-01-01

    In the lightning-fast world of intelligent control and cutting-edge computing, it is vitally important to stay abreast of developments that seem to follow each other without pause. This publication features the very latest and some of the very best current research in the field, with 32 revised and extended research articles written by prominent researchers in the field. Culled from contributions to the key 2011 conference Advances in Intelligent Control and Innovative Computing, held in Hong Kong, the articles deal with a wealth of relevant topics, from the most recent work in artificial intelligence and decision-supporting systems, to automated planning, modelling and simulation, signal processing, and industrial applications. Not only does this work communicate the current state of the art in intelligent control and innovative computing, it is also an illuminating guide to up-to-date topics for researchers and graduate students in the field. The quality of the contents is absolutely assured by the high pro...

  14. A Holistic Approach to Interdisciplinary Innovation Supported by a Simple Tool

    DEFF Research Database (Denmark)

    Denise J. Stokholm, Marianne

    2008-01-01

    Innovation is recognised as a strategy to achieve competitive businesses and products. Managing innovation at all levels requires integration of knowledge and interdisciplinary cooperation. Different understandings and approaches to innovation between professions often result in communication...... problems. To overcome this barrier a common ground is needed. This paper describes a holistic approach to innovation and presents a simple tool for facilitating cooperation on a diversity of innovation matters. It describes the development and use of the tool and demonstrates its capacity to support...

  15. Developing Anticipatory Life Cycle Assessment Tools to Support Responsible Innovation

    Science.gov (United States)

    Wender, Benjamin

    Several prominent research strategy organizations recommend applying life cycle assessment (LCA) early in the development of emerging technologies. For example, the US Environmental Protection Agency, the National Research Council, the Department of Energy, and the National Nanotechnology Initiative identify the potential for LCA to inform research and development (R&D) of photovoltaics and products containing engineered nanomaterials (ENMs). In this capacity, application of LCA to emerging technologies may contribute to the growing movement for responsible research and innovation (RRI). However, existing LCA practices are largely retrospective and ill-suited to support the objectives of RRI. For example, barriers related to data availability, rapid technology change, and isolation of environmental from technical research inhibit application of LCA to developing technologies. This dissertation focuses on development of anticipatory LCA tools that incorporate elements of technology forecasting, provide robust explorations of uncertainty, and engage diverse innovation actors in overcoming retrospective approaches to environmental assessment and improvement of emerging technologies. Chapter one contextualizes current LCA practices within the growing literature articulating RRI and identifies the optimal place in the stage gate innovation model to apply LCA. Chapter one concludes with a call to develop anticipatory LCA---building on the theory of anticipatory governance---as a series of methodological improvements that seek to align LCA practices with the objectives of RRI. Chapter two provides a framework for anticipatory LCA, identifies where research from multiple disciplines informs LCA practice, and builds off the recommendations presented in the preceding chapter. Chapter two focuses on crystalline and thin film photovoltaics (PV) to illustrate the novel framework, in part because PV is an environmentally motivated technology undergoing extensive R&D efforts and

  16. Nuclear and radiation applications in industry: Tools for innovation

    International Nuclear Information System (INIS)

    Machi, S.; Iyer, R.

    1994-01-01

    Applications of nuclear and radiation technologies have been contributing to industrial efficiency, energy conservation, and environmental protection for many years. Some of these are: Manufacturing industries: Radiation processing technologies are playing increasing roles during manufacturing of such everyday products as wire and cable, automobile tires, plastic films and sheets, and surface materials. Production processes: Other techniques employing radioisotope gauges are indispensable for on-line thickness measurements during paper, plastic, and steel plate production. Processing and quality checks are made using nucleonic control systems that are common features of industrial production lines. Sterilization of medical products using electron beam accelerators or cobalt-60 radiation is better than the conventional methods. Industrial safety and product quality: Non-destructive examination or testing using gamma- or X-ray radiography is widely used for checking welds, casting, machinery, and ceramics to ensure quality and safety. Additionally, radiotracer techniques are unique tools for the optimization of chemical processes in reactors, leakage detection, and wear and corrosion studies, for example. Environmental protection: An innovative technology using electron beams to simultaneously remove sulfur dioxide (SO 2 ) and nitrogen oxides (NO x ) has been under development. The electron beam technology is very cost competitive and its byproduct can be used as agricultural fertilizer

  17. Value Innovation in Learner-Centered Design. How to Develop Valuable Learning Tools

    Science.gov (United States)

    Breuer, Henning; Schwarz, Heinrich; Feller, Kristina; Matsumoto, Mitsuji

    2014-01-01

    This paper shows how to address technological, cultural and social transformations with empirically grounded innovation. Areas in transition such as higher education and learning techniques today bring about new needs and opportunities for innovative tools and services. But how do we find these tools? The paper argues for using a strategy of…

  18. Early Learning Assessment Innovation in South Africa: A Locally Appropriate Monitoring Tool

    Science.gov (United States)

    Dawes, Andrew; Biersteker, Linda; Girdwood, Elizabeth; Snelling, Matthew; Tredoux, C. G.

    2018-01-01

    In 2015, Innovation Edge commissioned the development of South Africa's first national-level preschool child assessment tool. The project's key innovations were that the tool should fairly assess children from across the cultural and socio-economic spectrum, be inexpensive in terms of equipment and administration costs, and be administered in…

  19. IT Tools for Foresight: The Integrated Insight and Response System of Deutsche Telekom Innovation Laboratories

    DEFF Research Database (Denmark)

    Rohrbeck, René; Thom, Nico; Arnold, Heinrich

    2015-01-01

    . The overall system consists of a tool for scanning for weak signals on change (PEACOQ Scouting Tool), a tool for collecting internal ideas (PEACOQ Gate 0.5), and a tool for triggering organizational responses (Foresight Landing page). Particularly the link to innovation management and R&D strategy...

  20. [Advance directives, a tool to humanize care].

    Science.gov (United States)

    Olmari-Ebbing, M; Zumbach, C N; Forest, M I; Rapin, C H

    2000-07-01

    The relationship between the patient and a medical care giver is complex specially as it implies to the human, juridical and practical points of view. It depends on legal and deontological considerations, but also on professional habits. Today, we are confronted to a fundamental modification of this relationship. Professional guidelines exist, but are rarely applied and rarely taught in universities. However, patients are eager to move from a paternalistic relationship to a true partnership, more harmonious and more respectful of individual values ("value based medicine"). Advance directives give us an opportunity to improve our practices and to provide care consistent with the needs and wishes of each patient.

  1. Innovation Training within the Australian Advanced Manufacturing Industry

    Science.gov (United States)

    Donovan, Jerome Denis; Maritz, Alex; McLellan, Andrew

    2013-01-01

    Innovation has emerged as a core driver for the future profitability and success of the manufacturing sector, and increasingly both governments and the private sector are examining ways to support the development of innovation capabilities within organisations. In this research, we have evaluated a government-funded innovation training course…

  2. Advanced tools for enhancing control room collaborations

    International Nuclear Information System (INIS)

    Abla, G.; Flanagan, S.M.; Peng, Q.; Burruss, J.R.; Schissel, D.P.

    2006-01-01

    The US National Fusion Collaboratory (NFC) project has been exploring a variety of computer and network technologies to develop a persistent, efficient, reliable and convenient collaborative environment for magnetic fusion research. One goal is to enhance remote and collocated team collaboration by integrating collaboration software tools into control room operations as well as with data analysis tools. To achieve this goal, the NFC recently introduced two new collaboration technologies into the DIII-D tokamak control room. The first technology is a high-resolution, large format Shared Display Wall (SDW). By creating a shared public display space and providing real time visual information about the multiple aspects of complex experiment activity, the large SDW plays an important role in increasing the rate of information dissemination and promoting interaction among team members. The second technology being implemented is the 'tokamak control room aware' Instant Messaging (IM) service. In addition to providing text-chat capabilities for research scientists, it enables them to automatically receive information about experiment operations and data analysis processes to remotely monitor the status of ongoing tokamak experiment. As a result, the IM service has become a unified portal interface for team collaboration and remote participation

  3. Advanced tools for enhancing control room collaborations

    Energy Technology Data Exchange (ETDEWEB)

    Abla, G. [General Atomics, P.O. Box 85608, San Diego, CA 92186 5608 (United States)]. E-mail: abla@fusion.gat.com; Flanagan, S.M. [General Atomics, P.O. Box 85608, San Diego, CA 92186 5608 (United States); Peng, Q. [General Atomics, P.O. Box 85608, San Diego, CA 92186 5608 (United States); Burruss, J.R. [General Atomics, P.O. Box 85608, San Diego, CA 92186 5608 (United States); Schissel, D.P. [General Atomics, P.O. Box 85608, San Diego, CA 92186 5608 (United States)

    2006-07-15

    The US National Fusion Collaboratory (NFC) project has been exploring a variety of computer and network technologies to develop a persistent, efficient, reliable and convenient collaborative environment for magnetic fusion research. One goal is to enhance remote and collocated team collaboration by integrating collaboration software tools into control room operations as well as with data analysis tools. To achieve this goal, the NFC recently introduced two new collaboration technologies into the DIII-D tokamak control room. The first technology is a high-resolution, large format Shared Display Wall (SDW). By creating a shared public display space and providing real time visual information about the multiple aspects of complex experiment activity, the large SDW plays an important role in increasing the rate of information dissemination and promoting interaction among team members. The second technology being implemented is the 'tokamak control room aware' Instant Messaging (IM) service. In addition to providing text-chat capabilities for research scientists, it enables them to automatically receive information about experiment operations and data analysis processes to remotely monitor the status of ongoing tokamak experiment. As a result, the IM service has become a unified portal interface for team collaboration and remote participation.

  4. Advanced reach tool (ART) : Development of the mechanistic model

    NARCIS (Netherlands)

    Fransman, W.; Tongeren, M. van; Cherrie, J.W.; Tischer, M.; Schneider, T.; Schinkel, J.; Kromhout, H.; Warren, N.; Goede, H.; Tielemans, E.

    2011-01-01

    This paper describes the development of the mechanistic model within a collaborative project, referred to as the Advanced REACH Tool (ART) project, to develop a tool to model inhalation exposure for workers sharing similar operational conditions across different industries and locations in Europe.

  5. Advanced REACH tool: A Bayesian model for occupational exposure assessment

    NARCIS (Netherlands)

    McNally, K.; Warren, N.; Fransman, W.; Entink, R.K.; Schinkel, J.; Van Tongeren, M.; Cherrie, J.W.; Kromhout, H.; Schneider, T.; Tielemans, E.

    2014-01-01

    This paper describes a Bayesian model for the assessment of inhalation exposures in an occupational setting; the methodology underpins a freely available web-based application for exposure assessment, the Advanced REACH Tool (ART). The ART is a higher tier exposure tool that combines disparate

  6. Assess your competitor collaboration to advance sustainability : an assessment tool

    NARCIS (Netherlands)

    DiVito, Lori; Garima, Sharma

    2016-01-01

    If your company is currently collaborating with competitors in order to advance sustainability, this tool will help you think about how to take that collaboration to the next level and achieve better results. If you’re still at the planning stages, this tool can help you reflect on where you would

  7. Advanced tools for in vivo skin analysis.

    Science.gov (United States)

    Cal, Krzysztof; Zakowiecki, Daniel; Stefanowska, Justyna

    2010-05-01

    A thorough examination of the skin is essential for accurate disease diagnostics, evaluation of the effectiveness of topically applied drugs and the assessment of the results of dermatologic surgeries such as skin grafts. Knowledge of skin parameters is also important in the cosmetics industry, where the effects of skin care products are evaluated. Due to significant progress in the electronics and computer industries, sophisticated analytic devices are increasingly available for day-to-day diagnostics. The aim of this article is to review several advanced methods for in vivo skin analysis in humans: magnetic resonance imaging, electron paramagnetic resonance, laser Doppler flowmetry and time domain reflectometry. The molecular bases of these techniques are presented, and several interesting applications in the field are discussed. Methods for in vivo assessment of the biomechanical properties of human skin are also reviewed.

  8. LASER CUTTING AS AN INNOVATIVE CREATIVITY TOOL IN TEXTILE DESIGN

    Directory of Open Access Journals (Sweden)

    Banu Hatice Gurcum

    2016-12-01

    Full Text Available Innovative technologies have become the most widespread rapid and flexible technique of cutting, welding, printing and coloring in fashion and textile sectors in a very short time. Laser systems as the most common used innovative technology engrave, cut, form, print, shade appropriated formatted drawings and sketches as well as they provide reliable placements for the lay out plans and precision cutting and the production sector rapid and qualified. The practical applications and conveniences that innovative Technologies employ, influence design process, designers can design in a more creative, rapid, precise and effective manner. Although design is a context where technology is effective, the style, mood and the background of the designer is still important. Designers while making innovative studies should take the advantage of the developing technologies in experimental processes and should combine technological opportunities with aesthetics. Textile designer as in all other domains of design, should harmonise with the change and should define his/her style with the innovative Technologies in an innovative manner and renew him/herself all the time. This study aims to classify laser cutting technology applications available in textile and fashion sector as well as to present the laser technology as a means of process, product, material innovation and explains the contributions of laser systems to creativity.

  9. The Water-Energy-Food Nexus: Advancing Innovative, Policy-Relevant Methods

    Science.gov (United States)

    Crootof, A.; Albrecht, T.; Scott, C. A.

    2017-12-01

    The water-energy-food (WEF) nexus is rapidly expanding in scholarly literature and policy settings as a novel way to address complex Anthropocene challenges. The nexus approach aims to identify tradeoffs and synergies of water, energy, and food systems, internalize social and environmental impacts, and guide development of cross-sectoral policies. However, a primary limitation of the nexus approach is the absence - or gaps and inconsistent use - of adequate methods to advance an innovative and policy-relevant nexus approach. This paper presents an analytical framework to identify robust nexus methods that align with nexus thinking and highlights innovative nexus methods at the frontier. The current state of nexus methods was assessed with a systematic review of 245 journal articles and book chapters. This review revealed (a) use of specific and reproducible methods for nexus assessment is uncommon - less than one-third of the reviewed studies present explicit methods; (b) nexus methods frequently fall short of capturing interactions among water, energy, and food - the very concept they purport to address; (c) assessments strongly favor quantitative approaches - 70% use primarily quantitative tools; (d) use of social science methods is limited (26%); and (e) many nexus methods are confined to disciplinary silos - only about one-quarter combine methods from diverse disciplines and less than one-fifth utilize both quantitative and qualitative approaches. Despite some pitfalls of current nexus methods, there are a host of studies that offer innovative approaches to help quantify nexus linkages and interactions among sectors, conceptualize dynamic feedbacks, and support mixed method approaches to better understand WEF systems. Applying our analytical framework to all 245 studies, we identify, and analyze herein, seventeen studies that implement innovative multi-method and cross-scalar tools to demonstrate promising advances toward improved nexus assessment. This paper

  10. ADEPT - an innovative tool to reduce worker exposure using virtual job planning

    International Nuclear Information System (INIS)

    Verzilov, Y.; Husain, A.; Trifanov, A.

    2011-01-01

    Advanced Dose Exposure Planning Tool (ADEPT) is Kinectrics' innovative solution for assisting nuclear station staff to effectively minimize worker dose during inspection and maintenance activities. ADEPT is a PC-based software that provides 3D virtual reality job simulations for radioactive environments around the CANDU reactor components, namely, the horizontal feeder cabinet, the vertical feeder cabinet and the reactor face. ADEPT allows users to walk through a virtual job plan and receive a live radiation dose estimate for the planned work. A worker dose estimation is based on a predetermined radiation field around reactor components and a user-defined job description. Radiation fields are based on the Outage Activity Transport Monitoring (OATM) data. (author)

  11. ADEPT - an innovative tool to reduce worker exposure using virtual job planning

    Energy Technology Data Exchange (ETDEWEB)

    Verzilov, Y.; Husain, A. [Kinectrics Inc., Toronto, Ontario (Canada); Trifanov, A. [SoftBeam Ltd., Montreal, Quebec (Canada)

    2011-07-01

    Advanced Dose Exposure Planning Tool (ADEPT) is Kinectrics' innovative solution for assisting nuclear station staff to effectively minimize worker dose during inspection and maintenance activities. ADEPT is a PC-based software that provides 3D virtual reality job simulations for radioactive environments around the CANDU reactor components, namely, the horizontal feeder cabinet, the vertical feeder cabinet and the reactor face. ADEPT allows users to walk through a virtual job plan and receive a live radiation dose estimate for the planned work. A worker dose estimation is based on a predetermined radiation field around reactor components and a user-defined job description. Radiation fields are based on the Outage Activity Transport Monitoring (OATM) data. (author)

  12. EPA Leadership on Science, Innovation, and Decision Support Tools for Addressing Current and Future Challenges.

    Science.gov (United States)

    Hecht, Alan D; Ferster, Aaron; Summers, Kevin

    2017-10-16

    When the U.S. Environmental Protection Agency (EPA) was established nearly 50 years ago, the nation faced serious threats to its air, land, and water, which in turn impacted human health. These threats were effectively addressed by the creation of EPA (in 1970) and many subsequent landmark environmental legislations which in turn significantly reduced threats to the Nation's environment and public health. A key element of historic legislation is research aimed at dealing with current and future problems. Today we face national and global challenges that go beyond classic media-specific (air, land, water) environmental legislation and require an integrated paradigm of action and engagement based on (1) innovation based on science and technology, (2) stakeholder engagement and collaboration, and (3) public education and support. This three-pronged approach recognizes that current environmental problems, include social as well as physical and environmental factors, are best addressed through collaborative problem solving, the application of innovation in science and technology, and multiple stakeholder engagement. To achieve that goal, EPA's Office of Research and Development (ORD) is working directly with states and local communities to develop and apply a suite of accessible decision support tools (DST) that aim to improve environmental conditions, protect human health, enhance economic opportunity, and advance a resilient and sustainability society. This paper showcases joint EPA and state actions to develop tools and approaches that not only meet current environmental and public health challenges, but do so in a way that advances sustainable, healthy, and resilient communities well into the future. EPA's future plans should build on current work but aim to effectively respond to growing external pressures. Growing pressures from megatrends are a major challenge for the new Administration and for cities and states across the country. The recent hurricanes hitting

  13. Innovation in Citizen Science – Perspectives on Science-Policy Advances

    Directory of Open Access Journals (Sweden)

    Susanne Hecker

    2018-04-01

    Full Text Available Citizen science is growing as a field of research with contributions from diverse disciplines, promoting innovation in science, society, and policy. Inter- and transdisciplinary discussions and critical analyses are needed to use the current momentum to evaluate, demonstrate, and build on the advances that have been made in the past few years. This paper synthesizes results of discussions at the first international citizen science conference of the European Citizen Science Association (ECSA in 2016 in Berlin, Germany, and distills major points of the discourse into key recommendations. To enhance innovation in science, citizen science needs to clearly demonstrate its scientific benefit, branch out across disciplines, and foster active networking and new formats of collaboration, including true co-design with participants. For fostering policy advances, it is important to embrace opportunities for policy-relevant monitoring and policy development and to work with science funders to find adequate avenues and evaluation tools to support citizen science. From a society angle it is crucial to engage with societal actors in various formats that suit participants and to evaluate two-way learning outcomes as well as to develop the transformative role of science communication. We hope that these key perspectives will promote citizen science progress at the science-society-policy interface.

  14. Innovation and the future of advanced dosimetry: 2D to 5D

    Science.gov (United States)

    Oldham, Mark

    2017-05-01

    Recent years have witnessed a remarkable evolution in the techniques, capabilities and applications of 3D dosimetry. Initially the goal was simple: to innovate new techniques capable of comprehensively measuring and verifying exquisitely intricate dose distributions from a paradigm changing emerging new therapy, IMRT. Basic questions emerged: how well were treatment planning systems modelling the complex delivery, and how could treatments be verified for safe use on patients? Since that time, equally significant leaps of innovation have continued in the technology of treatment delivery. In addition, clinical practice has been transformed by the addition of on-board imaging capabilities, which tend to hypo-fractionation strategies and margin reduction. The net result is a high stakes treatment setting where the clinical morbidity of any unintended treatment deviation is exacerbated by the combination of highly conformal dose distributions given with reduced margins with fractionation regimens unfriendly to healthy tissue. Not surprisingly this scenario is replete with challenges and opportunities for new and improved dosimetry systems. In particular tremendous interest exists in comprehensive 3D dosimetry systems, and systems that can resolve the dose in moving structures (4D) and even in deforming structures (5D). Despite significant progress in the capability of multi-dimensional dosimetry systems, it is striking that true 3D dosimetry systems are today largely found in academic institutions or specialist clinics. The reasons will be explored. We will highlight innovations occurring both in treatment delivery and in advanced dosimetry methods designed to verify them, and explore current and future opportunities for advanced dosimetry tools in clinical practice and translational research.

  15. An Engineering Educator's Decision Support Tool for Improving Innovation in Student Design Projects

    Science.gov (United States)

    Ozaltin, Nur Ozge; Besterfield-Sacre, Mary; Clark, Renee M.

    2015-01-01

    Learning how to design innovatively is a critical process skill for undergraduate engineers in the 21st century. To this end, our paper discusses the development and validation of a Bayesian network decision support tool that can be used by engineering educators to make recommendations that positively impact the innovativeness of product designs.…

  16. idSpace Tooling and Training for collaborative distributed product innovation

    NARCIS (Netherlands)

    Rutjens, Marjo; Bitter-Rijpkema, Marlies; Grube, Pascal; Heider, Thomas

    2009-01-01

    Rutjens, M., Bitter-Rijpkema, M., Grube, P. P., & Heider, T. (2009). idSpace Tooling and Training for collaborative distributed product innovation. Workshop during the e-Learning Baltic conference. June, 17-19, 2009, Rostock, Germany.

  17. Recent advances in systems metabolic engineering tools and strategies.

    Science.gov (United States)

    Chae, Tong Un; Choi, So Young; Kim, Je Woong; Ko, Yoo-Sung; Lee, Sang Yup

    2017-10-01

    Metabolic engineering has been playing increasingly important roles in developing microbial cell factories for the production of various chemicals and materials to achieve sustainable chemical industry. Nowadays, many tools and strategies are available for performing systems metabolic engineering that allows systems-level metabolic engineering in more sophisticated and diverse ways by adopting rapidly advancing methodologies and tools of systems biology, synthetic biology and evolutionary engineering. As an outcome, development of more efficient microbial cell factories has become possible. Here, we review recent advances in systems metabolic engineering tools and strategies together with accompanying application examples. In addition, we describe how these tools and strategies work together in simultaneous and synergistic ways to develop novel microbial cell factories. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Innovative leasing engineering as tool for synchronization of innovative, leasing and buying cycles

    Science.gov (United States)

    Yaskova, Natalia; Alekseeva, Tatyana

    2017-10-01

    This article suggests a new principle of cyclic synchronization of innovative, leasing and buying cycles in construction “innovative leasing engineering” which facilitates the accelerated transition of the national economy to the innovative way of development. Cyclical nature of economic phenomena is not only their immanent property, but also the subject of economic analysis. Modern format of decision making management requires analysis of the many cycles which fill any kind of activity. Accounting and reconciliation of construction, design, investment, buying, reproduction, leasing and other cycles is important for investment and construction sphere from the point of view of necessity for synchronization and position of determining the nature of trends in sectoral development.

  19. Understanding Managers Decision Making Process for Tools Selection in the Core Front End of Innovation

    DEFF Research Database (Denmark)

    Appio, Francesco P.; Achiche, Sofiane; McAloone, Tim C.

    2011-01-01

    New product development (NPD) describes the process of bringing a new product or service to the market. The Fuzzy Front End (FFE) of Innovation is the term describing the activities happening before the product development phase of NPD. In the FFE of innovation, several tools are used to facilita...... hypotheses are tested. A preliminary version of a theoretical model depicting the decision process of managers during tools selection in the FFE is proposed. The theoretical model is built from the constructed hypotheses....

  20. Innovative R.E.A. tools for integrated bathymetric survey

    Science.gov (United States)

    Demarte, Maurizio; Ivaldi, Roberta; Sinapi, Luigi; Bruzzone, Gabriele; Caccia, Massimo; Odetti, Angelo; Fontanelli, Giacomo; Masini, Andrea; Simeone, Emilio

    2017-04-01

    sensors useful for seabed analysis. The very stable platform located on the top of the USV allows for taking-off and landing of the RPAS. By exploiting its higher power autonomy and load capability, the USV will be used as a mothership for the RPAS. In particular, during the missions the USV will be able to furnish recharging possibility for the RPAS and it will be able to function as a bridge for the communication between the RPAS and its control station. The main advantage of the system is the remote acquisition of high-resolution bathymetric data from RPAS in areas where the possibility to have a systematic and traditional survey are few or none. These tools (USV carrying an RPAS with Hyperspectral camera) constitute an innovative and powerful system that gives to the Emergency Response Unit the right instruments to react quickly. The developing of this support could be solve the classical conflict between resolution, needed to capture the fine scale variability and coverage, needed for the large environmental phenomena, with very high variability over a wide range of spatial and temporal scales as the coastal environment.

  1. Beyond bionics: a tool of innovation and sustainability

    NARCIS (Netherlands)

    Trotto, A.; Cianfanelli, E.; Feijs, L.M.G.; Kyffin, S.

    2006-01-01

    Formal and typological innovation and ecological sustainability are essential premises for "meaningful" products. Applying bionics to the design process is a valuable approach to convey those concepts. A didactic research led at the Department of Industrial Design of the University of Florence has

  2. Methods and tools for innovation management procuring enterprises

    OpenAIRE

    A. V. Bogomolov

    2013-01-01

    The traditional methods of quality control of grain, dock-led feasibility, proposed and tested in practice near-mill elevator innovative methods of management organization, introduction of resource-saving technologies, different allow using «piezo electronic sensor» more quickly and accurately detect early damage of grain of wheat and ensure its further storage without loss of quality are described.

  3. Reply to "transforming oncology care": advancing value, accessing innovation.

    Science.gov (United States)

    Paradis, Rebecca

    2015-09-01

    Alternative payment models in oncology are already successfully standardizing care, curbing costs, and improving the patient experience. Yet, it is unclear whether decision makers are adequately considering patient access to innovation when creating these models, which could have severe consequences for a robust innovation ecosystem and the lives of afflicted patients. The suggested chart includes recommendations on: Allowing for the adoption of new, promising therapies; Promoting the measurement of patient-centered outcomes; and Providing support for personalized medicine.

  4. Firm Readiness Level for Innovation Projects: A New Decision-Making Tool for Innovation Managers

    Directory of Open Access Journals (Sweden)

    Daniel Galvez

    2018-03-01

    Full Text Available Innovation projects represent a major challenge for business managers due to their associated uncertainty degree. The already existing methodologies to support the innovation projects are aimed at piloting them and establishing the management stages in a flexible and agile way during their deployment. This paper proposes a complementary ex-ante methodology that seeks to aid the decision-making of companies to choose whether or not to launch a potential innovation project. This methodology evaluates to what extent the technological system of the company has the minimum required maturity degree of competencies to successfully achieve the innovation project. Thus, in first instance, an innovation project is characterized according to its novelty degree; both inside the company and in its environment. Subsequently, according to the previous characterization, the future project will have an impact on the technological system of the company. The capabilities of the firm are represented by a set of good practices associated with the innovation projects’ management that the company is able to deploy. Finally, the minimum maturity degree required by a particular project of these practices is determined. Then, the gap between the maturity requirement profile and the current profile of the company is established enabling to decide on the implementation of the project or not.

  5. A Firm-Level Innovation Management Framework and Assessment Tool for Increasing Competitiveness

    Directory of Open Access Journals (Sweden)

    Sorin Cohn

    2013-10-01

    Full Text Available Innovation depends on much more than just technology and R&D. It is a means to an end – competitive success and higher market value – and it needs to be managed strategically and methodically for tangible corporate performance where it matters: in the market. This article introduces a comprehensive corporate innovation management framework (v-CIM and a targeted competitiveness assessment tool (i-TCA. Properly used by corporate leaders, this framework and its associated tool enable innovation managers to decide on priorities for competitive development, adopt appropriate innovation strategies to meet corporate goals, monitor progress, make adjustments, and help create and maintain a culture of innovation that is aligned with business goals.

  6. Innovation pressure : service companies race to improve their horizontal multi-frac completion tools and techniques

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, G.

    2010-11-15

    This article described innovations in horizontal multi-frac completion tools and techniques that service companies are providing in the field. BJ Services has developed coiled tubing technology for annular fracing in cased-hole horizontal wells, which enables producers to complete with closer spacing, and frac sleeves that form an integral part of the casing string. Trican Well Service Ltd. recommends pumping through casing to create an unobstructed conduit, reducing friction and allowing the high pressure needed to create complex fractures. The Burst Port System is designed for selective fracturing: integrated casing collars that contain pre-milled ports are placed into the horizontal well casing; the C2C, a selective fracturing cup tool with a unique pressure equalization valve, straddles the port; and pressure is built up the designated burst point, leaving an isolated conduit to the formation. Recent chemical innovations include ecologically safe frac fluids and fluids designed to work in cold temperatures. The Viking PW (produced water) system can accommodate produced water, recycled water, and recycled oil-based frac systems and tolerates other contaminants. Non-toxic EcoClean fluids protect water wells and aquifers during treatments. A new frac fluid modifies the surface property of proppant, allowing deeper penetration with less settling and banking. Advances in well simulation technology, micro-seismic techniques that can listen and locate fracing events in real time, and directional drillers were also described. Low gas prices are inspiring companies to improve efficiency ad lower costs, which is creating a greater emphasis on development. 2 figs.

  7. Method and Tools for Development of Advanced Instructional Systems

    NARCIS (Netherlands)

    Arend, J. van der; Riemersma, J.B.J.

    1994-01-01

    The application of advanced instructional systems (AISs), like computer-based training systems, intelligent tutoring systems and training simulators, is widely spread within the Royal Netherlands Army. As a consequence there is a growing interest in methods and tools to develop effective and

  8. Advanced Computing Tools and Models for Accelerator Physics

    International Nuclear Information System (INIS)

    Ryne, Robert; Ryne, Robert D.

    2008-01-01

    This paper is based on a transcript of my EPAC'08 presentation on advanced computing tools for accelerator physics. Following an introduction I present several examples, provide a history of the development of beam dynamics capabilities, and conclude with thoughts on the future of large scale computing in accelerator physics

  9. Methods and tools for innovation management procuring enterprises

    Directory of Open Access Journals (Sweden)

    A. V. Bogomolov

    2013-01-01

    Full Text Available The traditional methods of quality control of grain, dock-led feasibility, proposed and tested in practice near-mill elevator innovative methods of management organization, introduction of resource-saving technologies, different allow using «piezo electronic sensor» more quickly and accurately detect early damage of grain of wheat and ensure its further storage without loss of quality are described.

  10. Value Innovation in Learner-Centered Design. How to Develop Valuable Learning Tools.

    Directory of Open Access Journals (Sweden)

    Henning Breuer

    2014-02-01

    Full Text Available This paper shows how to address technological, cultural and social transformations with empirically grounded innovation. Areas in transition such as higher education and learning techniques today bring about new needs and opportunities for innovative tools and services. But how do we find these tools? The paper argues for using a strategy of (user value innovation that creatively combines ethnographic methods with strategic industry analysis. By focusing on unmet and emerging needs ethnographic research identifies learner values, needs and challenges but does not determine solutions. Blue-ocean strategy tools can identify new opportunities that alter existing offerings but give weak guidance on what will be most relevant to users. The triangulation of both is illustrated through an innovation project in higher education.

  11. Life Cycle Assessment as Entrepreneurial Tool for Business Management and Green Innovations

    Directory of Open Access Journals (Sweden)

    Cassiano Moro Piekarski

    2013-01-01

    Full Text Available A transition for a green economy has encouraged companies to use new tools which promote internal corporate entrepreneurship, increase the competitiveness and achieve sustainable results. This article presented a theoretical discussion of how the Life Cycle Assessment (LCA can presents as an entrepreneurial tool for modern business management and green innovation. Studies of LCA were analyzed showing benefits and applications in the areas of strategic planning, production, process of development of products, search and development, social and environmental responsibility, and marketing. As for green innovations, there were analyzed studies of innovations in products, processes and services. The tool assists in making sustainable decisions, fortifies the management of the business processes, the management of operations and the promotion of greener innovations.

  12. Advanced and sustainable fuel cycles for innovative reactor systems

    International Nuclear Information System (INIS)

    Glatz, J. P.; Malmbeck, R.; Purroy, D. S.; Soucek, P.; Inoue, T.; Uozumi, K.

    2007-01-01

    The key objective of nuclear energy systems of the future as defined by the Generation IV road map is to provide a sustainable energy generation for the future. It includes the requirement to minimize the nuclear waste produced and thereby notably reduce the long term stewardship burden in the future. It is therefore evident that the corresponding fuel cycles will play a central role in trying to achieve these goals by creating clean waste streams which contain almost exclusively the fission products. A new concept based on a grouped separation of actinides is widely discussed in this context, but it is of course a real challenge to achieve this type of separation since technologies available today have been developed to separate actinides from each other. In France, the CEA has launched extensive research programs in the ATALANTE facility in Marcoule to develop the advanced fuel cycles for new generation reactor systems. In this so called global actinide management (GAM) concept, the actinides are extracted in a sequence of chemical reactions (grouped actinide extraction (GANEX)) and immediately reintroduced in the fuel fabrication process is to use all actinides in the energy production process. The new group separation processes can be derived as in this case from aqueous techniques but also from so-called pyrochemical partitioning processes. Significant progress was made in recent years for both routes in the frame of the European research projects PARTNEW, PYROREP and EUROPART, mainly devoted to the separation of minor actinides in the frame of partitioning and transmutation (P and T) studies. The fuels used in the new generation reactors will be significantly different from the commercial fuels of today. Because of the fuel type and the very high burn-ups reached, pyrometallurgical reprocessing could be the preferred method. The limited solubility of some of the fuel materials in acidic aqueous solutions, the possibility to have an integrated irradiation and

  13. An Engineering Innovation Tool: Providing Science Educators a Picture of Engineering in Their Classroom

    Science.gov (United States)

    Ross, Julia Myers; Peterman, Karen; Daugherty, Jenny L.; Custer, Rodney L.

    2018-01-01

    An Engineering Innovation Tool was designed to support science teachers as they navigate the opportunities and challenges the inclusion of engineering affords by providing a useful tool to be used within the professional development environment and beyond. The purpose of this manuscript is to share the design, development and substance of the tool…

  14. Biotechnology: a tool for sustainable innovation in agriculture

    International Nuclear Information System (INIS)

    Nocera, Rachele

    2015-01-01

    Feed 9.6 billion people, according to UN projections, will populate the planet in 2050. This is the challenge that agriculture is called to deal and that will be one of the topics carriers EXPO 2015. The answer to food needs of a population growing, in particular in the Countries in the developing world, will certainly not unique, but the road seems marked: it is that of an i ntensification sustainable a griculture, supported by innovation and research, able to enhance agricultural yields without adding to the budget input necessary for the production (energy, earth, water). [it

  15. Building a competitive regional innovation environment : the regional development platform method as a tool for regional innovation policy

    OpenAIRE

    Harmaakorpi, Vesa

    2004-01-01

    The study focuses on building a regional innovation policy tool that takes into account the demands of the present techno-economic and socio-institutional paradigms. Regions are seen to be strongly dependent on their history. The competitiveness of a region is based on the regional resource configurations. In a turbulent world these resource configurations have to be renewed over time setting demands for regional dynamic capabilities. This study emphasises five regional dynamic capabilities: ...

  16. Latest Community Coordinated Modeling Center (CCMC) services and innovative tools supporting the space weather research and operational communities.

    Science.gov (United States)

    Mendoza, A. M. M.; Rastaetter, L.; Kuznetsova, M. M.; Mays, M. L.; Chulaki, A.; Shim, J. S.; MacNeice, P. J.; Taktakishvili, A.; Collado-Vega, Y. M.; Weigand, C.; Zheng, Y.; Mullinix, R.; Patel, K.; Pembroke, A. D.; Pulkkinen, A. A.; Boblitt, J. M.; Bakshi, S. S.; Tsui, T.

    2017-12-01

    The Community Coordinated Modeling Center (CCMC), with the fundamental goal of aiding the transition of modern space science models into space weather forecasting while supporting space science research, has been serving as an integral hub for over 15 years, providing invaluable resources to both space weather scientific and operational communities. CCMC has developed and provided innovative web-based point of access tools varying from: Runs-On-Request System - providing unprecedented global access to the largest collection of state-of-the-art solar and space physics models, Integrated Space Weather Analysis (iSWA) - a powerful dissemination system for space weather information, Advanced Online Visualization and Analysis tools for more accurate interpretation of model results, Standard Data formats for Simulation Data downloads, and Mobile apps to view space weather data anywhere to the scientific community. In addition to supporting research and performing model evaluations, CCMC also supports space science education by hosting summer students through local universities. In this poster, we will showcase CCMC's latest innovative tools and services, and CCMC's tools that revolutionized the way we do research and improve our operational space weather capabilities. CCMC's free tools and resources are all publicly available online (http://ccmc.gsfc.nasa.gov).

  17. Strategic thinking as a tool for technological innovation in smes

    Directory of Open Access Journals (Sweden)

    Darcy Luz Mendoza

    2016-11-01

    Full Text Available The present study aims to design strategies that allow smes to watch from one strategic thinking technological innovation, in order to meet the financial core objective to grow and be competitive in the market. The article illustrates how smes can get enterprise development from a planned technological innovation from its institutional philosophy, it imposes a challenge for these companies, the establishment of an action plan and building articulated development scenarios involve and benefit all stakeholders generating competitive advantages. The study was conducted using a survey of 95 businesses in La Guajira department, having as strategy exposed by Daft (2005 who finds that competitive strategy is about being different, select a number of different activities that other been selected to offer a unique mix of value. The research results suggest that smes do not have a department that demonstrates technological structure that have made a process for the development and successful commercialization of new or improved products, either that these companies think the strategies from its institutional philosophy, putting into practice the strategic thinking.

  18. Advanced subgrid modeling for Multiphase CFD in CASL VERA tools

    International Nuclear Information System (INIS)

    Baglietto, Emilio; Gilman, Lindsey; Sugrue, Rosie

    2014-01-01

    This work introduces advanced modeling capabilities that are being developed to improve the accuracy and extend the applicability of Multiphase CFD. Specifics of the advanced and hardened boiling closure model are described in this work. The development has been driven by new physical understanding, derived from the innovative experimental techniques available at MIT. A new experimental-based mechanistic approach to heat partitioning is proposed. The model introduces a new description of the bubble evaporation, sliding and interaction on the heated surface to accurately capture the evaporation occurring at the heated surface, while also tracking the local surface conditions. The model is being assembled to cover an extended application area, up to Critical Heat Flux (CHF). The accurate description of the bubble interaction, effective microlayer and dry surface area are considered to be the enabling quantities towards innovated CHF capturing methodologies. Further, improved mechanistic force-balance models for bubble departure predictions and lift-off diameter predictions are implemented in the model. Studies demonstrate the influence of the newly implemented partitioning components. Finally, the development work towards a more consistent and integrated hydrodynamic closure is presented. The main objective here is to develop a set of robust momentum closure relations which focuses on the specific application to PWR conditions, but will facilitate the application to other geometries, void fractions, and flow regimes. The innovative approach considers local flow conditions on a cell-by-cell basis to ensure robustness. Closure relations of interest initially include drag, lift, and turbulence dispersion, with near wall corrections applied for both drag and lift. (author)

  19. Animal-assisted interventions as innovative tools for mental health

    Directory of Open Access Journals (Sweden)

    Francesca Cirulli

    2011-12-01

    Full Text Available There is a growing interest for the potential health benefits of human-animal interactions. Although scientific evidence on the effects is far from being consistent, companion animals are used with a large number of human subjects, ranging from children to elderly people, who benefit most from emotional support. Based on a comprehensive review of the literature, this paper examines the potential for domesticated animals, such as dogs, for providing emotional and physical opportunities to enrich the lives of many frail subjects. In particular, we focus on innovative interventions, including the potential use of dogs to improve the life of emotionally-impaired children, such as those affected by autism spectrum disorders. Overall an ever increasing research effort is needed to search for the mechanism that lie behind the human-animal bond as well as to provide standardized methodologies for a cautious and effective use of animal-assisted interventions.

  20. Research Game: an innovative educational tool for teachers and students

    Directory of Open Access Journals (Sweden)

    Franca Sangiorgio

    2014-12-01

    Full Text Available This contribution describes ‘Research Game’, a game produced in a Lifelong Learning Programme-Comenius Project (The European Scientific Research Game which aims at motivating secondary school students through the experience of the excitement of scientific research. The project proposes practical and didactic works which combine theoretical activities with ICT in order to introduce students to the scientific research. Students collaborated internationally across Europe, to build hypotheses, carry out research, test the validity of their hypothesis and finalize a theory based on their findings. On the project platform (www.researchgame.eu/platform teachers and students registered, created a team, interacted on a forum space, played and learned science in a new innovative way. Here, the students shared their research findings with other groups of all Europe; finally competed online playing a serious game and showing to be able to apply the scientific method.

  1. Infographics: An Innovative Tool to Capture Consumers' Attention

    Science.gov (United States)

    Niebaum, Kelly; Cunningham-Sabo, Leslie; Carroll, Jan; Bellows, Laura

    2015-01-01

    Using infographics as educational tools has emerged as a strategy to reach consumers in today's information-saturated environment. Through the use of engaging and informative graphics, educators can deliver meaningful messages tailored to targeted audiences. Varying types of effectively designed infographics can be used to capture the attention of…

  2. An innovative simulation tool for waste to energy generation opportunities

    Directory of Open Access Journals (Sweden)

    Bilal Abderezzak

    2017-03-01

    Full Text Available The new world energy policies encourage the use of renewable energy sources with clean technologies, and abandon progressively the fossil fuel dependence. Another energy generation trend called commonly the “Waste-to-Energy” solution, uses organic waste as a response for two major problems: energy generation and waste management. Thanks to the anaerobic digestion, the organic waste can provide a biogas composed essentially from Carbone dioxide (CO2 and Methane (CH4. This work aims essentially to help students, researchers and even decision makers to consider the importance of biogas generation. The proposed tool is the last version of our previous tool which is enhanced and completed. It presents the potential to produce biogas of any shortlisted kind of waste, including also some energy valorization ways. A technical economical data are introduced for eventual feasibility studies.

  3. Anvil Forecast Tool in the Advanced Weather Interactive Processing System

    Science.gov (United States)

    Barrett, Joe H., III; Hood, Doris

    2009-01-01

    Meteorologists from the 45th Weather Squadron (45 WS) and National Weather Service Spaceflight Meteorology Group (SMG) have identified anvil forecasting as one of their most challenging tasks when predicting the probability of violations of the Lightning Launch Commit Criteria and Space Shuttle Flight Rules. As a result, the Applied Meteorology Unit (AMU) was tasked to create a graphical overlay tool for the Meteorological Interactive Data Display System (MIDDS) that indicates the threat of thunderstorm anvil clouds, using either observed or model forecast winds as input. The tool creates a graphic depicting the potential location of thunderstorm anvils one, two, and three hours into the future. The locations are based on the average of the upper level observed or forecasted winds. The graphic includes 10 and 20 n mi standoff circles centered at the location of interest, as well as one-, two-, and three-hour arcs in the upwind direction. The arcs extend outward across a 30 sector width based on a previous AMU study that determined thunderstorm anvils move in a direction plus or minus 15 of the upper-level wind direction. The AMU was then tasked to transition the tool to the Advanced Weather Interactive Processing System (AWIPS). SMG later requested the tool be updated to provide more flexibility and quicker access to model data. This presentation describes the work performed by the AMU to transition the tool into AWIPS, as well as the subsequent improvements made to the tool.

  4. From the abstract to the concrete - Implementation of an innovative tool in home care.

    Science.gov (United States)

    Kajamaa, Anu; Schulz, Klaus-Peter

    2018-02-01

    Background The implementation of innovations in practice is a critical factor for change and development processes in health and home care. We therefore analyze how an innovative tool - a mobility agreement to maintain physical mobility of home care clients - was implemented in Finnish home care. Methods Our study involves ethnographic research of 13 home care visits, two years after the mobility agreement was implemented. We analyze the emergence of contradictions, the motives of the actors and the use of artifacts supporting or inhibiting the implementation. Two in-depth cases illustrate the implementation of the mobility agreement in home care visits. Findings Our findings show that, first, to achieve practice change and development, the innovation implementation requires the overcoming of contradictions in the implementation process. Second, it calls for the emergence of a shared motive between the actors to transform the abstract concept of an innovation into a concrete practice. Third, artifacts, customary to the clients are important in supporting the implementation process. Fourth, the implementation brings about a modification of the innovation and the adopting social system. Conclusions Innovation implementation should be seen as a transformation process of an abstract concept into a concrete practice, enabled by the actors involved. Concept design and implementation should be closely linked. In health/home care innovation management, the implementation of innovations needs to be understood as a complex collective learning process. Results can be far reaching - in our case leading to change of home care workers' professional understanding and elderly clients' mobility habits.

  5. Knowledge Preservation and Consolidation through an Innovative Multimedia Tool

    International Nuclear Information System (INIS)

    Corniani, E.

    2013-01-01

    The JRC (Joint Research Centre) is the European Commission’s in-house science service. It provides the science for policy decisions, with a view to ensuring that the EU achieves its Europe 2020 goals for a productive economy as well as a safe, secure and sustainable future. The JRC plays a key role in the European Research Area and reinforces its multi-disciplinarity by networking extensively with leading scientific organisations in the Member States, Associated Countries and worldwide. The presentation is about • JRC methodology in Knowledge Preservation; • A Multimedia tool developed for preserving knowledge on WWER reactors; • EC involvement on Fast Reactors

  6. TESPI (Tool for Environmental Sound Product Innovation): a simplified software tool to support environmentally conscious design in SMEs

    Science.gov (United States)

    Misceo, Monica; Buonamici, Roberto; Buttol, Patrizia; Naldesi, Luciano; Grimaldi, Filomena; Rinaldi, Caterina

    2004-12-01

    TESPI (Tool for Environmental Sound Product Innovation) is the prototype of a software tool developed within the framework of the "eLCA" project. The project, (www.elca.enea.it)financed by the European Commission, is realising "On line green tools and services for Small and Medium sized Enterprises (SMEs)". The implementation by SMEs of environmental product innovation (as fostered by the European Integrated Product Policy, IPP) needs specific adaptation to their economic model, their knowledge of production and management processes and their relationships with innovation and the environment. In particular, quality and costs are the main driving forces of innovation in European SMEs, and well known barriers exist to the adoption of an environmental approach in the product design. Starting from these considerations, the TESPI tool has been developed to support the first steps of product design taking into account both the quality and the environment. Two main issues have been considered: (i) classic Quality Function Deployment (QFD) can hardly be proposed to SMEs; (ii) the environmental aspects of the product life cycle need to be integrated with the quality approach. TESPI is a user friendly web-based tool, has a training approach and applies to modular products. Users are guided through the investigation of the quality aspects of their product (customer"s needs and requirements fulfilment) and the identification of the key environmental aspects in the product"s life cycle. A simplified check list allows analyzing the environmental performance of the product. Help is available for a better understanding of the analysis criteria. As a result, the significant aspects for the redesign of the product are identified.

  7. Patent data mining: a tool for accelerating HIV vaccine innovation.

    Science.gov (United States)

    Clark, K; Cavicchi, J; Jensen, K; Fitzgerald, R; Bennett, A; Kowalski, S P

    2011-05-31

    Global access to advanced vaccine technologies is challenged by the interrelated components of intellectual property (IP) management strategies, technology transfer (legal and technical) capabilities and the capacity necessary for accelerating R&D, commercialization and delivery of vaccines. Due to a negative association with the management of IP, patents are often overlooked as a vast resource of freely available, information akin to scientific journals as well as business and technological information and trends fundamental for formulating policies and IP management strategies. Therefore, a fundamental step towards facilitating global vaccine access will be the assembly, organization and analysis of patent landscapes, to identify the amount of patenting, ownership (assignees) and fields of technology covered. This is critical for making informed decisions (e.g., identifying licensees, building research and product development collaborations, and ascertaining freedom to operate). Such information is of particular interest to the HIV vaccine community where the HIV Vaccine Enterprise, have voiced concern that IP rights (particularly patents and trade secrets) may prevent data and materials sharing, delaying progress in research and development of a HIV vaccine. We have compiled and analyzed a representative HIV vaccine patent landscape for a prime-boost, DNA/adenoviral vaccine platform, as an example for identifying obstacles, maximizing opportunities and making informed IP management strategy decisions towards the development and deployment of an efficacious HIV vaccine. Copyright © 2011 Elsevier Ltd. All rights reserved.

  8. Debt swaps as an innovative tool for financing renewable energies

    International Nuclear Information System (INIS)

    Gugler, A.

    1999-01-01

    The emergence of a so-called 'secondary market' for Third World debt papers laid the foundations for different types of debt swaps or debt conversions. A debt conversion is a financial transaction in which a 'converter' (or investor) exchanges (swaps) a debt denominated in a hard currency for a domestic debt payable in local currency by the debtor government. This operation is attractive for the investor because it can imply a significant leverage, since the debt paper is purchased at an often substantial discount on the secondary market, whereas the debtor government will redeem it at a rate above the purchase price. Debt swaps can play a role as an additional source of development finance, but their contribution should not be overestimated. Over the last ten years, debt-for-development and debt-for-nature swaps have generated an estimated US$ 1 billion in local currency. In recent years, debt swaps originating with non-governmental organizations have considerably slowed, probably due to rising prices for commercial debt titles. On the other hand, it is expected that there will be an increase of official debt conversions in the future. Since they can be an attractive financing tool, debt swaps could also be used in order to fund investments in or credit facilities for alternative energies. (orig.)

  9. Digital marketing as a tool for innovation and business leverage

    Directory of Open Access Journals (Sweden)

    Andrea Cristina Marin

    2018-01-01

    Full Text Available This article presents a research that sought to clarify and evidence the evolution of the historical scenario of marketing science and the sales processes attributed to it, contextualizing how such changes of concepts through their epochs of evolution and their paradigms were applied by companies as to the present day. The speed of structural changes in the new economy and the opportunities generated by current information and communication technologies require companies to continually rethink their business, analyzing new marketing concepts that outperform traditional marketing and can be used in the digital environment as a way of attracting and relationship with customers. This is a descriptive bibliographical research with a qualitative focus, which includes a brief historical survey about the science of Marketing, as well as an investigation that discusses the technology attributed to Digital Marketing as a tool for leveraging business in the contemporary model of today's companies, based on the works of the authors who discuss the theme, such as Las Casas (2009; At the end of the research it was possible to verify that the impact of the new information and communication technologies transformed the way in which the companies are currently related using new forms of advertisements to intensify and adapt the competitiveness established by the current market parameters to other competing companies .

  10. Innovation

    Science.gov (United States)

    EPA frames innovation as critical to the protection of human health and the environment through initiatives such as sustainable practices, innovative research, prize competitions, innovation awards, partnerships, and community activities.

  11. Interoperable mesh and geometry tools for advanced petascale simulations

    International Nuclear Information System (INIS)

    Diachin, L; Bauer, A; Fix, B; Kraftcheck, J; Jansen, K; Luo, X; Miller, M; Ollivier-Gooch, C; Shephard, M S; Tautges, T; Trease, H

    2007-01-01

    SciDAC applications have a demonstrated need for advanced software tools to manage the complexities associated with sophisticated geometry, mesh, and field manipulation tasks, particularly as computer architectures move toward the petascale. The Center for Interoperable Technologies for Advanced Petascale Simulations (ITAPS) will deliver interoperable and interchangeable mesh, geometry, and field manipulation services that are of direct use to SciDAC applications. The premise of our technology development goal is to provide such services as libraries that can be used with minimal intrusion into application codes. To develop these technologies, we focus on defining a common data model and data-structure neutral interfaces that unify a number of different services such as mesh generation and improvement, front tracking, adaptive mesh refinement, shape optimization, and solution transfer operations. We highlight the use of several ITAPS services in SciDAC applications

  12. Using Developmental Evaluation as a Design Thinking Tool for Curriculum Innovation in Professional Higher Education

    Science.gov (United States)

    Leonard, Simon N.; Fitzgerald, Robert N.; Riordan, Geoffrey

    2016-01-01

    This paper argues for the use of "developmental" evaluation as a design-based research tool for sustainable curriculum innovation in professional higher education. Professional education is multi-faceted and complex with diverse views from researchers, professional practitioners, employers and the world of politics leaving little…

  13. 3D data processing with advanced computer graphics tools

    Science.gov (United States)

    Zhang, Song; Ekstrand, Laura; Grieve, Taylor; Eisenmann, David J.; Chumbley, L. Scott

    2012-09-01

    Often, the 3-D raw data coming from an optical profilometer contains spiky noises and irregular grid, which make it difficult to analyze and difficult to store because of the enormously large size. This paper is to address these two issues for an optical profilometer by substantially reducing the spiky noise of the 3-D raw data from an optical profilometer, and by rapidly re-sampling the raw data into regular grids at any pixel size and any orientation with advanced computer graphics tools. Experimental results will be presented to demonstrate the effectiveness of the proposed approach.

  14. Advanced software tools for digital loose part monitoring systems

    International Nuclear Information System (INIS)

    Ding, Y.

    1996-01-01

    The paper describes two software modules as analysis tools for digital loose part monitoring systems. The first module is called acoustic module which utilizes the multi-media features of modern personal computers to replay the digital stored short-time bursts with sufficient length and in good quality. This is possible due to the so-called puzzle technique developed at ISTec. The second module is called classification module which calculates advanced burst parameters and classifies the acoustic events in pre-defined classes with the help of an artificial multi-layer perception neural network trained with the back propagation algorithm. (author). 7 refs, 7 figs

  15. Advanced software tools for digital loose part monitoring systems

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Y [Institute for Safety Technology (ISTec) GmbH, Garching (Germany)

    1997-12-31

    The paper describes two software modules as analysis tools for digital loose part monitoring systems. The first module is called acoustic module which utilizes the multi-media features of modern personal computers to replay the digital stored short-time bursts with sufficient length and in good quality. This is possible due to the so-called puzzle technique developed at ISTec. The second module is called classification module which calculates advanced burst parameters and classifies the acoustic events in pre-defined classes with the help of an artificial multi-layer perception neural network trained with the back propagation algorithm. (author). 7 refs, 7 figs.

  16. Commissioning software tools at the Advanced Photon Source

    International Nuclear Information System (INIS)

    Emery, L.

    1995-01-01

    A software tool-oriented approach has been adopted in the commissioning of the Advanced Photon Source (APS) at Argonne National Laboratory, particularly in the commissioning of the Positron Accumulator Ring (PAR). The general philosophy is to decompose a complicated procedure involving measurement, data processing, and control into a series of simpler steps, each accomplished by a generic toolkit program. The implementation is greatly facilitated by adopting the SDDS (self-describing data set protocol), which comes with its own toolkit. The combined toolkit has made accelerator physics measurements easier. For instance, the measurement of the optical functions of the PAR and the beamlines connected to it have been largely automated. Complicated measurements are feasible with a combination of tools running independently

  17. Review on advanced composite materials boring mechanism and tools

    Science.gov (United States)

    Shi, Runping; Wang, Chengyong

    2011-05-01

    With the rapid development of aviation and aerospace manufacturing technology, advanced composite materials represented by carbon fibre reinforced plastics (CFRP) and super hybrid composites (fibre/metal plates) are more and more widely applied. The fibres are mainly carbon fibre, boron fibre, Aramid fiber and Sic fibre. The matrixes are resin matrix, metal matrix and ceramic matrix. Advanced composite materials have higher specific strength and higher specific modulus than glass fibre reinforced resin composites of the 1st generation. They are widely used in aviation and aerospace industry due to their high specific strength, high specific modulus, excellent ductility, anticorrosion, heat-insulation, sound-insulation, shock absorption and high&low temperature resistance. They are used for radomes, inlets, airfoils(fuel tank included), flap, aileron, vertical tail, horizontal tail, air brake, skin, baseboards and tails, etc. Its hardness is up to 62~65HRC. The holes are greatly affected by the fibre laminates direction of carbon fibre reinforced composite material due to its anisotropy when drilling in unidirectional laminates. There are burrs, splits at the exit because of stress concentration. Besides there is delamination and the hole is prone to be smaller. Burrs are caused by poor sharpness of cutting edge, delamination, tearing, splitting are caused by the great stress caused by high thrust force. Poorer sharpness of cutting edge leads to lower cutting performance and higher drilling force at the same time. The present research focuses on the interrelation between rotation speed, feed, drill's geometry, drill life, cutting mode, tools material etc. and thrust force. At the same time, holes quantity and holes making difficulty of composites have also increased. It requires high performance drills which won't bring out defects and have long tool life. It has become a trend to develop super hard material tools and tools with special geometry for drilling

  18. Advance of technological innovations of electric power in 2012

    International Nuclear Information System (INIS)

    Mayumi, Akihiko; Tanaka, Masanori; Takebe, Toshiro

    2013-01-01

    Twelve companies in Japan reported on the technological innovations in 2012. The Japan Atomic Power Company mainly studied five projects; (1) control of wall thinning of the secondary system in PWR by injection of molybdic acid, (2) application of pipe test method using electromagnetic acoustic resonance to existing equipment, (3) developed high performance Co-60 crud removal resin for Tsuruga Power Station Unit 2, (4) improvement of technology for safety of core in FBR, and (5) improvement of technology for coolant of FBR by dispersing nano-particles in liquid sodium metal. Tokyo Electric Power Company developed mainly three projects; (1) the support for the mental health care activities by industry protection staff at the Fukushima Daiichi and Daini Nuclear Power Plant, (2) laboratory test method using non-radioactive cesium for performance of decontamination reagent, and (3) decontamination effects estimation code (DeConEP). Hokuriku Electric Power Company reported the operations management measures in accordance with the safety enhancement measures to Shika nuclear power station. Other nine reports are published by Hokkaido Electric Power Co., Inc. Tohoku Electric Power Co., Inc. Chubu Electric Power Co., Inc., The Kansai Electric Power Co., Inc., The Chugoku Electric Power Co., Inc., Shikoku Electric Power Co., Inc., Kyushu Electric Power Co., Inc., Okinawa Electric Power Company Inc. and J-Power. (S.Y.)

  19. NOTE: An innovative phantom for quantitative and qualitative investigation of advanced x-ray imaging technologies

    Science.gov (United States)

    Chiarot, C. B.; Siewerdsen, J. H.; Haycocks, T.; Moseley, D. J.; Jaffray, D. A.

    2005-11-01

    Development, characterization, and quality assurance of advanced x-ray imaging technologies require phantoms that are quantitative and well suited to such modalities. This note reports on the design, construction, and use of an innovative phantom developed for advanced imaging technologies (e.g., multi-detector CT and the numerous applications of flat-panel detectors in dual-energy imaging, tomosynthesis, and cone-beam CT) in diagnostic and image-guided procedures. The design addresses shortcomings of existing phantoms by incorporating criteria satisfied by no other single phantom: (1) inserts are fully 3D—spherically symmetric rather than cylindrical; (2) modules are quantitative, presenting objects of known size and contrast for quality assurance and image quality investigation; (3) features are incorporated in ideal and semi-realistic (anthropomorphic) contexts; and (4) the phantom allows devices to be inserted and manipulated in an accessible module (right lung). The phantom consists of five primary modules: (1) head, featuring contrast-detail spheres approximate to brain lesions; (2) left lung, featuring contrast-detail spheres approximate to lung modules; (3) right lung, an accessible hull in which devices may be placed and manipulated; (4) liver, featuring conrast-detail spheres approximate to metastases; and (5) abdomen/pelvis, featuring simulated kidneys, colon, rectum, bladder, and prostate. The phantom represents a two-fold evolution in design philosophy—from 2D (cylindrically symmetric) to fully 3D, and from exclusively qualitative or quantitative to a design accommodating quantitative study within an anatomical context. It has proven a valuable tool in investigations throughout our institution, including low-dose CT, dual-energy radiography, and cone-beam CT for image-guided radiation therapy and surgery.

  20. An innovative phantom for quantitative and qualitative investigation of advanced x-ray imaging technologies

    International Nuclear Information System (INIS)

    Chiarot, C B; Siewerdsen, J H; Haycocks, T; Moseley, D J; Jaffray, D A

    2005-01-01

    Development, characterization, and quality assurance of advanced x-ray imaging technologies require phantoms that are quantitative and well suited to such modalities. This note reports on the design, construction, and use of an innovative phantom developed for advanced imaging technologies (e.g., multi-detector CT and the numerous applications of flat-panel detectors in dual-energy imaging, tomosynthesis, and cone-beam CT) in diagnostic and image-guided procedures. The design addresses shortcomings of existing phantoms by incorporating criteria satisfied by no other single phantom: (1) inserts are fully 3D-spherically symmetric rather than cylindrical; (2) modules are quantitative, presenting objects of known size and contrast for quality assurance and image quality investigation; (3) features are incorporated in ideal and semi-realistic (anthropomorphic) contexts; and (4) the phantom allows devices to be inserted and manipulated in an accessible module (right lung). The phantom consists of five primary modules: (1) head, featuring contrast-detail spheres approximate to brain lesions; (2) left lung, featuring contrast-detail spheres approximate to lung modules; (3) right lung, an accessible hull in which devices may be placed and manipulated; (4) liver, featuring conrast-detail spheres approximate to metastases; and (5) abdomen/pelvis, featuring simulated kidneys, colon, rectum, bladder, and prostate. The phantom represents a two-fold evolution in design philosophy-from 2D (cylindrically symmetric) to fully 3D, and from exclusively qualitative or quantitative to a design accommodating quantitative study within an anatomical context. It has proven a valuable tool in investigations throughout our institution, including low-dose CT, dual-energy radiography, and cone-beam CT for image-guided radiation therapy and surgery. (note)

  1. A retrospective analysis of funding and focus in US advanced fission innovation

    Science.gov (United States)

    Abdulla, A.; Ford, M. J.; Morgan, M. G.; Victor, D. G.

    2017-08-01

    Deep decarbonization of the global energy system will require large investments in energy innovation and the deployment of new technologies. While many studies have focused on the expenditure that will be needed, here we focus on how government has spent public sector resources on innovation for a key carbon-free technology: advanced nuclear. We focus on nuclear power because it has been contributing almost 20% of total US electric generation, and because the US program in this area has historically been the world’s leading effort. Using extensive data acquired through the Freedom of Information Act, we reconstruct the budget history of the Department of Energy’s program to develop advanced, non-light water nuclear reactors. Our analysis shows that—despite spending 2 billion since the late 1990s—no advanced design is ready for deployment. Even if the program had been well designed, it still would have been insufficient to demonstrate even one non-light water technology. It has violated much of the wisdom about the effective execution of innovative programs: annual funding varies fourfold, priorities are ephemeral, incumbent technologies and fuels are prized over innovation, and infrastructure spending consumes half the budget. Absent substantial changes, the possibility of US-designed advanced reactors playing a role in decarbonization by mid-century is low.

  2. Innovations in building regulation and control for advancing sustainability in buildings (I)

    NARCIS (Netherlands)

    Meacham, B.; Visscher, H.J.; Meijer, F.M.; Chan, C.; Chan, E.; Laubscher, J.; Neng Kwei Sung, J.; Dodds, B.; Serra, J.; Tenorio, J.A.; Echeverria, J.B.; Sanches-Ostiz, A.

    2014-01-01

    This session brings together policy-makers, government officials, researchers and others to present perspectives on how innovation in building regulation and control, such as performancebased approaches, are currently being used to advance sustainability concepts in buildings, and where and how we

  3. Integrating Social Neuroscience and Social Work: Innovations for Advancing Practice-Based Research

    Science.gov (United States)

    Matto, Holly C.; Strolin-Goltzman, Jessica

    2010-01-01

    Throughout the social work profession, there is ongoing interest in building a social science agenda that can address the complex practice-based questions faced by social work professionals today. Methodological innovations and unique funding opportunities have already significantly advanced research on social work practice. Still, there is…

  4. Advancing Management Innovation: Synthesizing Processes, Levels of Analysis, and Change Agents

    NARCIS (Netherlands)

    Volberda, H.W.; van den Bosch, F.; Mihalache, R.O.

    2014-01-01

    Despite the mounting evidence that innovation in management can fuel competitive advantage, we still know relatively little about how firms introduce new ways of managing. The goal of this introductory essay—and the Themed Section it introduces—is to advance this knowledge. To this end, we first

  5. Systematic review of innovative ablative therapies for the treatment of locally advanced pancreatic cancer

    NARCIS (Netherlands)

    Rombouts, S. J. E.; Vogel, J. A.; van Santvoort, H. C.; van Lienden, K. P.; van Hillegersberg, R.; Busch, O. R. C.; Besselink, M. G. H.; Molenaar, I. Q.

    2015-01-01

    BackgroundLocally advanced pancreatic cancer (LAPC) is associated with a very poor prognosis. Current palliative (radio)chemotherapy provides only a marginal survival benefit of 2-3 months. Several innovative local ablative therapies have been explored as new treatment options. This systematic

  6. Lean production tools and decision latitude enable conditions for innovative learning in organizations: a multilevel analysis.

    Science.gov (United States)

    Fagerlind Ståhl, Anna-Carin; Gustavsson, Maria; Karlsson, Nadine; Johansson, Gun; Ekberg, Kerstin

    2015-03-01

    The effect of lean production on conditions for learning is debated. This study aimed to investigate how tools inspired by lean production (standardization, resource reduction, visual monitoring, housekeeping, value flow analysis) were associated with an innovative learning climate and with collective dispersion of ideas in organizations, and whether decision latitude contributed to these associations. A questionnaire was sent out to employees in public, private, production and service organizations (n = 4442). Multilevel linear regression analyses were used. Use of lean tools and decision latitude were positively associated with an innovative learning climate and collective dispersion of ideas. A low degree of decision latitude was a modifier in the association to collective dispersion of ideas. Lean tools can enable shared understanding and collective spreading of ideas, needed for the development of work processes, especially when decision latitude is low. Value flow analysis played a pivotal role in the associations. Copyright © 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  7. Otolaryngology--head and neck surgery in undergraduate medical education: advances and innovations.

    Science.gov (United States)

    Fung, Kevin

    2015-02-01

    Medical students graduate with the knowledge and skills to be undifferentiated general physicians. Otolaryngology-head and neck surgery (OtoHNS) is an essential component of primary healthcare, but is disproportionately under-represented in undergraduate medical education (UME). Advances and innovations in educational technology may represent an exciting and creative solution to this important problem. Failure to meet this educational need will result in substantial downstream effects in primary healthcare delivery. The objectives of this study were to 1) demonstrate current deficits in OtoHNS teaching at the UME level; 2) develop, validate, and critically appraise educational innovations that may enrich OtoHNS teaching in medical school curricula; and 3) propose a process for standardization of learning objectives for OtoHNS in UME as it relates to development and deployment of such educational tools. A white paper, prepared as a Triological Society thesis, which consolidates a prospective 10-year investigation of the problem of and potential solutions for under-representation of OtoHNS in UME. Cited datasets include multicenter surveys, cohort studies, and prospective, randomized controlled trials. A series of published and unpublished data were synthesized that addresses the following: 1) the current state of OtoHNS teaching at the UME level with respect to content, volume, structure, and methods; and 2) educational innovations including e-learning and simulation with emphasis on validity and learning effectiveness. Educational innovations specific to postgraduate (residency) training were excluded. Data support the observation that there is uniformly disproportionate under-representation of OtoHNS within UME curricula. Medical school graduates, especially those pursuing primary care specialties, report poor overall comfort levels in managing OtoHNS problems. A series of novel teaching methods were developed and validated using e-learning and simulation

  8. Towards Innovative Geospatial Tools for Fit-For Land Rights Mapping

    Science.gov (United States)

    Koeva, M.; Bennett, R.; Gerke, M.; Crommelinck, S.; Stöcker, C.; Crompvoets, J.; Ho, S.; Schwering, A.; Chipofya, M.; Schultz, C.; Zein, T.; Biraro, M.; Alemie, B.; Wayumba, R.; Kundert, K.

    2017-09-01

    In large parts of sub Saharan Africa it remains an ongoing challenging to map millions of unrecognized land rights. Existing approaches for recognizing these rights have proven inappropriate in many cases. A new generation of tools needs to be developed to support faster, cheaper, easier, and more responsible land rights mapping. This is the main goal of its4land, an European Commission Horizon 2020 project that aims to develop innovative tools inspired by the continuum of land rights, fit-for-purpose land administration, and cadastral intelligence. its4land is using strategic collaboration between the EU and East Africa to deliver innovative, scalable, and transferrable ICT solutions. The innovation process incorporates a broad range of stakeholders and emergent geospatial technologies, including smart sketchmaps, UAVs, automated feature extraction, as well as geocloud services. The aim is to combine innovative technologies, capture the specific needs, market opportunities and readiness of end-users in the domain of land tenure information recording in Eastern Africa. The project consists of a four year work plan, € 3.9M funding, and eight consortium partners collaborating with stakeholders from six case study locations in Ethiopia, Kenya, and Rwanda. The major tasks include tool development, prototyping, and demonstration for local, national, regional, and international interest groups. The case locations cover different land uses such as: urban, peri-urban, rural smallholder, and (former) pastoralist. This paper describes the project's activities within the first 18 months and covers barriers discovered, lessons learned and results achieved.

  9. A Business intelligence tool for studying value co-creation and innovation

    DEFF Research Database (Denmark)

    Tanev, Stoyan; Ruskov, Petko; Georgiev, Lachezar

    2011-01-01

    Value co-creation is an emerging marketing and innovation paradigm describing a broader opening of the firm to its customers by providing them with the opportunity to become active participants in the design and development of personalized products, services and experiences. However......, there is not yet a fully satisfactory theoretical vision about its distinctive characteristics as compared to more traditional value creation approaches. One of the challenges in studying value co-creation is the lack of business intelligence (BI) tools that can be used in the conceptualization of value co...... is the relationship between the degree of firms’ involvement in value co-creation activities and their innovativeness....

  10. Locally advanced cervix carcinoma - innovation in combined modality therapy

    International Nuclear Information System (INIS)

    Swift, Patrick S.

    1996-01-01

    Locally advanced cervical carcinoma continues to be a challenge to the clinician due to local failure as well as systemic metastases. Standard intracavitary and external beam techniques result in local control rates of only 35-65%, with long term survival rates of 25-60% in patients with state IIIA-IVA disease, indicating the need to identify new treatment strategies. Optimization programs for remote-afterloading interstitial brachytherapy allow the delivery of higher local doses of radiation to volumes that more closely approximate tumor target volumes as identified on MR scans, leading to improved therapeutic ratios. Identification of subsets of patients more likely to fail standard therapy, either locally or systemically, may be possible through such techniques as in vivo measurements of hypoxia with Eppendorf oxygen electrodes, interstitial fluid pressure measurements, the Comet assay, and nitroimidazole binding methods. Traditional chemotherapies, administered in either a neoadjuvant role or concomitantly with radiation have been disappointing in prospective trials. A variety of new agents are being investigated to determine if they can increase the frequency or duration of complete response. The taxanes, with response rates of 17-23% by themselves, are being assessed as potential radiosensitizers. The camptotheicin CRT-11 (Irinotecan) has demonstrated activity in platinum resistant cervix cancer, with response rates of 24%. Bioradiotherapeutic approaches, using 13-cis-retinoic acid and interferon-2a, are undergoing phase II studies. Neoangiogenesis inhibitors and vaccines against HPV are also being examined. The aggressive pursuit of techniques that help identify those patients most likely to fail, that allow the delivery of higher radiation doses more safely to the target volume, and that incorporate the use of more effective systemic therapies is necessary to improve the outcome for this disease

  11. The industrial research project: “Blu-Archeosys – Innovative Technologies and Advanced Systems as Support in Underwater Archaeology”

    Directory of Open Access Journals (Sweden)

    Salvatore Lorusso

    2003-02-01

    Full Text Available The reasons of the research about new technologies as support in naval and underwater archaeology or, more generally, in waters archaeology are various and described in this work, where the characteristics of the research project “BLU-ARCHEOSYS – Innovative Technologies and Advanced SYStems as Support in Underwater ARCHaeology” are illustrated. This industrial research project faces problems regarding innovative technologies and instruments in waters archaeology and it comprehends synergic steps and joined works among skilled professionals that have the competences to interpret qualitative and/or quantitative data within an artistic – historical and technical – historical study, also with the involvement of various public and private institutions. The BLUARCHEOSYS project has, in fact, the objective to create technologies that have a reply in underwater archaeology and contemporaneously in other sectors. In particular, starting from the methodological way that spans from the discovery in underwater or subaerial environment to the collocation of the objects in museums, the intent is to support the different methodological stages with specific tools and innovative technologies. The education project, presented to the Ministry with the research one, is articulated in the different branches of artistic-historical character, of the management, normative and operative character, and of the technical-diagnostic-material-preservative character. The professionals will have not only theoretical knowledge about standard and consolidated technologies, but they will be also experts about methodologies, in particular the diagnostic ones, that put in field the innovative tools evaluated in the project, with consequent competitive advantage in the working field, more and more demanding specific sector competences.

  12. Clinical Holistic Health: Advanced Tools for Holistic Medicine

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2006-01-01

    Full Text Available According to holistic medical theory, the patient will heal when old painful moments, the traumatic events of life that are often called “gestalts”, are integrated in the present “now”. The advanced holistic physician’s expanded toolbox has many different tools to induce this healing, some that are more dangerous and potentially traumatic than others. The more intense the therapeutic technique, the more emotional energy will be released and contained in the session, but the higher also is the risk for the therapist to lose control of the session and lose the patient to his or her own dark side. To avoid harming the patient must be the highest priority in holistic existential therapy, making sufficient education and training an issue of highest importance. The concept of “stepping up” the therapy by using more and more “dramatic” methods to get access to repressed emotions and events has led us to a “therapeutic staircase” with ten steps: (1 establishing the relationship; (2 establishing intimacy, trust, and confidentiality; (3 giving support and holding; (4 taking the patient into the process of physical, emotional, and mental healing; (5 social healing of being in the family; (6 spiritual healing — returning to the abstract wholeness of the soul; (7 healing the informational layer of the body; (8 healing the three fundamental dimensions of existence: love, power, and sexuality in a direct way using, among other techniques, “controlled violence” and “acupressure through the vagina”; (9 mind-expanding and consciousness-transformative techniques like psychotropic drugs; and (10 techniques transgressing the patient's borders and, therefore, often traumatizing (for instance, the use of force against the will of the patient.We believe that the systematic use of the staircase will greatly improve the power and efficiency of holistic medicine for the patient and we invite a broad cooperation in scientifically testing the

  13. Clinical holistic health: advanced tools for holistic medicine.

    Science.gov (United States)

    Ventegodt, Søren; Clausen, Birgitte; Nielsen, May Lyck; Merrick, Joav

    2006-02-24

    According to holistic medical theory, the patient will heal when old painful moments, the traumatic events of life that are often called "gestalts", are integrated in the present "now". The advanced holistic physician's expanded toolbox has many different tools to induce this healing, some that are more dangerous and potentially traumatic than others. The more intense the therapeutic technique, the more emotional energy will be released and contained in the session, but the higher also is the risk for the therapist to lose control of the session and lose the patient to his or her own dark side. To avoid harming the patient must be the highest priority in holistic existential therapy, making sufficient education and training an issue of highest importance. The concept of "stepping up" the therapy by using more and more "dramatic" methods to get access to repressed emotions and events has led us to a "therapeutic staircase" with ten steps: (1) establishing the relationship; (2) establishing intimacy, trust, and confidentiality; (3) giving support and holding; (4) taking the patient into the process of physical, emotional, and mental healing; (5) social healing of being in the family; (6) spiritual healing--returning to the abstract wholeness of the soul; (7) healing the informational layer of the body; (8) healing the three fundamental dimensions of existence: love, power, and sexuality in a direct way using, among other techniques, "controlled violence" and "acupressure through the vagina"; (9) mind-expanding and consciousness-transformative techniques like psychotropic drugs; and (10) techniques transgressing the patient's borders and, therefore, often traumatizing (for instance, the use of force against the will of the patient). We believe that the systematic use of the staircase will greatly improve the power and efficiency of holistic medicine for the patient and we invite a broad cooperation in scientifically testing the efficiency of the advanced holistic

  14. Advances in Intelligent Modelling and Simulation Simulation Tools and Applications

    CERN Document Server

    Oplatková, Zuzana; Carvalho, Marco; Kisiel-Dorohinicki, Marek

    2012-01-01

    The human capacity to abstract complex systems and phenomena into simplified models has played a critical role in the rapid evolution of our modern industrial processes and scientific research. As a science and an art, Modelling and Simulation have been one of the core enablers of this remarkable human trace, and have become a topic of great importance for researchers and practitioners. This book was created to compile some of the most recent concepts, advances, challenges and ideas associated with Intelligent Modelling and Simulation frameworks, tools and applications. The first chapter discusses the important aspects of a human interaction and the correct interpretation of results during simulations. The second chapter gets to the heart of the analysis of entrepreneurship by means of agent-based modelling and simulations. The following three chapters bring together the central theme of simulation frameworks, first describing an agent-based simulation framework, then a simulator for electrical machines, and...

  15. Innovation killers: how financial tools destroy your capacity to do new things.

    Science.gov (United States)

    Christensen, Clayton M; Kaufman, Stephen P; Shih, Willy C

    2008-01-01

    Most companies aren't half as innovative as their senior executives want them to be (or as their marketing claims suggest they are). What's stifling innovation? There are plenty of usual suspects, but the authors finger three financial tools as key accomplices. Discounted cash flow and net present value, as commonly used, underestimate the real returns and benefits of proceeding with an investment. Most executives compare the cash flows from innovation against the default scenario of doing nothing, assuming--incorrectly--that the present health of the company will persist indefinitely if the investment is not made. In most situations, however, competitors' sustaining and disruptive investments over time result in deterioration of financial performance. Fixed- and sunk-cost conventional wisdom confers an unfair advantage on challengers and shackles incumbent firms that attempt to respond to an attack. Executives in established companies, bemoaning the expense of building new brands and developing new sales and distribution channels, seek instead to leverage their existing brands and structures. Entrants, in contrast, simply create new ones. The problem for the incumbent isn't that the challenger can spend more; it's that the challenger is spared the dilemma of having to choose between full-cost and marginal-cost options. The emphasis on short-term earnings per share as the primary driver of share price, and hence shareholder value creation, acts to restrict investments in innovative long-term growth opportunities. These are not bad tools and concepts in and of themselves, but the way they are used to evaluate investments creates a systematic bias against successful innovation. The authors recommend alternative methods that can help managers innovate with a much more astute eye for future value.

  16. Tourists' acceptance of advanced technology-based innovations for promoting arts and culture

    NARCIS (Netherlands)

    Pantano, E.; Corvello, V.

    2014-01-01

    Advanced technologies are able to influence tourists' decisions. They can be exploited for attracting touristic flows towards cultural destinations. In particular, virtual tours are new tools based on advanced 3D graphics that can be useful for promoting arts and culture. In this paper, we test

  17. Student and Preceptor Advancement in a Dedicated Education Site: Innovation in Clinical Education for Advanced Practice Nurses.

    Science.gov (United States)

    Hall, Katherine C; Diffenderfer, Sandy K; Stidham, April; Mullins, Christine M

    2018-04-19

    In the 1990s, dedicated education units transformed undergraduate preceptorships, but graduate preceptorships remain static. The dyadic nurse practitioner preceptorship model supports an environment where faculty, students, and preceptors may overlook nuances that affect the teaching-learning process. This article describes an innovative clinical education model, Student and Preceptor Advancement in a Dedicated Education Site, designed to improve preceptorships for advanced practice nurses. The focus is on adaptations made to facilitate use in advanced practice nursing programs.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

  18. Innovation

    DEFF Research Database (Denmark)

    Nielsen, Janni; Yaganeh, Suzanne; Bloch Rasmussen, Leif

    2013-01-01

    This paper contributes to a theoretical discussion of creation of innovation with participants in, or outside, organisations. We address the creation of innovation with a complex theoretical understanding drawing on the Scandinavian and the Participatory Design tradition introducing two approaches...... to the processes of innovation. We ask if innovation can be initiated and enhanced looking at two collaborative approaches; participatory innovation (PIN) and cooperative innovation (COIN). We invite to dialogue and reflections on PIN’s conflict and creative frictions on one side and COIN’s complexity......, complementarity in diversity and the didactic scaffolding of the innovation process on the other side. Our contribution focuses on the methods and practices for facilitation of co-creating activities between different groups leading to cooperation, and innovation in thinking....

  19. DengueTools: innovative tools and strategies for the surveillance and control of dengue.

    Science.gov (United States)

    Wilder-Smith, Annelies; Renhorn, Karl-Erik; Tissera, Hasitha; Abu Bakar, Sazaly; Alphey, Luke; Kittayapong, Pattamaporn; Lindsay, Steve; Logan, James; Hatz, Christoph; Reiter, Paul; Rocklöv, Joacim; Byass, Peter; Louis, Valérie R; Tozan, Yesim; Massad, Eduardo; Tenorio, Antonio; Lagneau, Christophe; L'Ambert, Grégory; Brooks, David; Wegerdt, Johannah; Gubler, Duane

    2012-01-01

    Dengue fever is a mosquito-borne viral disease estimated to cause about 230 million infections worldwide every year, of which 25,000 are fatal. Global incidence has risen rapidly in recent decades with some 3.6 billion people, over half of the world's population, now at risk, mainly in urban centres of the tropics and subtropics. Demographic and societal changes, in particular urbanization, globalization, and increased international travel, are major contributors to the rise in incidence and geographic expansion of dengue infections. Major research gaps continue to hamper the control of dengue. The European Commission launched a call under the 7th Framework Programme with the title of 'Comprehensive control of Dengue fever under changing climatic conditions'. Fourteen partners from several countries in Europe, Asia, and South America formed a consortium named 'DengueTools' to respond to the call to achieve better diagnosis, surveillance, prevention, and predictive models and improve our understanding of the spread of dengue to previously uninfected regions (including Europe) in the context of globalization and climate change.The consortium comprises 12 work packages to address a set of research questions in three areas:Research area 1: Develop a comprehensive early warning and surveillance system that has predictive capability for epidemic dengue and benefits from novel tools for laboratory diagnosis and vector monitoring.Research area 2: Develop novel strategies to prevent dengue in children.Research area 3: Understand and predict the risk of global spread of dengue, in particular the risk of introduction and establishment in Europe, within the context of parameters of vectorial capacity, global mobility, and climate change.In this paper, we report on the rationale and specific study objectives of 'DengueTools'. DengueTools is funded under the Health theme of the Seventh Framework Programme of the European Community, Grant Agreement Number: 282589 Dengue Tools.

  20. Development of Innovative Tools and Models for Vocational Education and Training in Central and Western Romania

    Directory of Open Access Journals (Sweden)

    Liviu Moldovan

    2009-12-01

    Full Text Available This paper presents an initiative developed by two partner universities from Romania and Norway entitled „Innovative Tools and models for Vocational Education and Training in Central and western Romania” (MoVE-IT financed by SEE mechanism [1]. It has the priority to develop human resource through promotion of education and training, by means of distance learning. The objective, legal issues, outcome and results and envisaged impact of the project are presented.

  1. Tools for advanced simulations to nuclear propulsion systems in rockets

    International Nuclear Information System (INIS)

    Torres Sepulveda, A.; Perez Vara, R.

    2004-01-01

    While chemical propulsion rockets have dominated space exploration, other forms of rocket propulsion based on nuclear power, electrostatic and magnetic drive, and other principles besides chemical reactions, have been considered from the earliest days of the field. The goal of most of these advanced rocket propulsion schemes is improved efficiency through higher exhaust velocities, in order to reduce the amount of fuel the rocket vehicle needs to carry, though generally at the expense of high thrust. Nuclear propulsion seems to be the most promising short term technology to plan realistic interplanetary missions. The development of a nuclear electric propulsion spacecraft shall require the development of models to analyse the mission and to understand the interaction between the related subsystems (nuclear reactor, electrical converter, power management and distribution, and electric propulsion) during the different phases of the mission. This paper explores the modelling of a nuclear electric propulsion (NEP) spacecraft type using EcosimPro simulation software. This software is a multi-disciplinary simulation tool with a powerful object-oriented simulation language and state-of-the-art solvers. EcosimPro is the recommended ESA simulation tool for environmental Control and Life Support Systems (ECLSS) and has been used successfully within the framework of the European activities of the International Space Station programme. Furthermore, propulsion libraries for chemical and electrical propulsion are currently being developed under ESA contracts to set this tool as standard usage in the propulsion community. At present, there is not any workable NEP spacecraft, but a standardized-modular, multi-purpose interplanetary spacecraft for post-2000 missions, called ISC-2000, has been proposed in reference. The simulation model presented on this paper is based on the preliminary designs for this spacecraft. (Author)

  2. Tools of integration of innovation-oriented machine-building enterprises in industrial park environment

    Directory of Open Access Journals (Sweden)

    К.О. Boiarynova

    2017-08-01

    Full Text Available The research is devoted to the development of the tools for the integration of innovation-oriented mechanical engineering enterprises into the environment of industrial park as functional economic systems, which are capable on the own development basis to provide the development of resident enterprises. The article analyzes the opportunities for the development of mechanical engineering enterprises. The formed structure of the mechanism of integration of mechanical engineering enterprises as functional economic systems into the industrial park environment is based on: 1 the development of participation programs in the industrial park of the mechanical engineering enterprises as an innovation-oriented partner, which foresees the development of the enterprise immediately and the development of other residents; 2 the provision of high-tech equipment of resident enterprises of industrial parks; 3 the creation of subsidiary-spin-out enterprises of large mechanical engineering enterprises for high-tech production in the industrial park. The author proposes the road map that reveals the procedures for the integration and functioning the investigated enterprises through interaction as well as in the ecosystem of the industrial park and in the general ecosystem of functioning, and the tools for providing economic functionality through economic and organizational proceedings at preventive, partner and resident phases of integration. The tools allow the innovation-oriented mechanical engineering enterprises to integrate into such territorial structures as industrial parks, this in complex will allow carrying out their purposes in the development of the real sector of the economy.

  3. Advanced Infusion Techniques with 3-D Printed Tooling

    Energy Technology Data Exchange (ETDEWEB)

    Nuttall, David [ORNL; Elliott, Amy M [ORNL; Post, Brian K [ORNL; Love, Lonnie J [ORNL

    2016-05-10

    The manufacturing of tooling for large, contoured surfaces for fiber-layup applications requires significant effort to understand the geometry and then to subtractively manufacture the tool. Traditional methods for the auto industry use clay that is hand sculpted. In the marine pleasure craft industry, the exterior of the model is formed from a foam lay-up that is either hand cut or machined to create smooth lines. Engineers and researchers at Oak Ridge National Laboratory s Manufacturing Demonstration Facility (ORNL MDF) collaborated with Magnum Venus Products (MVP) in the development of a process for reproducing legacy whitewater adventure craft via digital scanning and large scale 3-D printed layup molds. The process entailed 3D scanning a legacy canoe form, converting that form to a CAD model, additively manufacturing (3-D Print) the mold tool, and subtractively finishing the mold s transfer surfaces. Future work will include applying a gelcoat to the mold transfer surface and infusing using vacuum assisted resin transfer molding, or VARTM principles, to create a watertight vessel. The outlined steps were performed on a specific canoe geometry found by MVP s principal participant. The intent of utilizing this geometry is to develop an energy efficient and marketable process for replicating complex shapes, specifically focusing on this particular watercraft, and provide a finished product for demonstration to the composites industry. The culminating part produced through this agreement has been slated for public presentation and potential demonstration at the 2016 CAMX (Composites and Advanced Materials eXpo) exposition in Anaheim, CA. Phase I of this collaborative research and development agreement (MDF-15-68) was conducted under CRADA NFE-15-05575 and was initiated on May 7, 2015, with an introduction to the MVP product line, and concluded in March of 2016 with the printing of and processing of a canoe mold. The project partner Magnum Venous Products (MVP) is

  4. MARKETING TOOLS FOR PROMOTING INNOVATIONS IN THE SYSTEM OF HIGHER EDUCATION

    Directory of Open Access Journals (Sweden)

    Natalya O. Kolchina

    2016-06-01

    Full Text Available Introduction: the article is concerned with the tools for promoting innovative educational products within the framework of the concept “Europe of knowledge” on the basis of education integration, researches and innovations. The relevance of the article is caused by increasing importance of promoting innovative products in the field of higher education through the means designed to popularize science not only among science professional, but also among the general public. Materials and Methods: the author uses descriptive method and analyzes the scholar literature on the promotion and introduction of innovative products in the field of education through the media. Results: the results show the need for using the exhibition activity parameters to introduce and implement the educational programmes “Tempus”, “Erasmus+”, and others, and to create relationship between universities and representatives of business communities from the partner countries. The authors emphasise the differences in the mechanism of impact on the target audience (a high school leaver, a student or a representative of a business community. The article presents a combination of essential elements in core objectives of the strategy “Europe 2020” (particularly in the context of priority of the rapid development and components of seven priority initiatives which determine the scheme for the strategic development of the EU member states in the field of education until 2020. Discussion and Conclusions: a professionally designed exposition, well-prepared advertising materials and adequate work with representatives of business communities and partner universities whihin the education exhibition can increase the number of applications to participate in the programme “Capicity-building in the field of higher education”. Promoting innovative products through using some marketing tools is differential in nature and indirectly related to the specifics of their posi

  5. DengueTools: innovative tools and strategies for the surveillance and control of dengue

    Directory of Open Access Journals (Sweden)

    Annelies Wilder-Smith

    2012-03-01

    Full Text Available Dengue fever is a mosquito-borne viral disease estimated to cause about 230 million infections worldwide every year, of which 25,000 are fatal. Global incidence has risen rapidly in recent decades with some 3.6 billion people, over half of the world's population, now at risk, mainly in urban centres of the tropics and subtropics. Demographic and societal changes, in particular urbanization, globalization, and increased international travel, are major contributors to the rise in incidence and geographic expansion of dengue infections. Major research gaps continue to hamper the control of dengue. The European Commission launched a call under the 7th Framework Programme with the title of ‘Comprehensive control of Dengue fever under changing climatic conditions’. Fourteen partners from several countries in Europe, Asia, and South America formed a consortium named ‘DengueTools’ to respond to the call to achieve better diagnosis, surveillance, prevention, and predictive models and improve our understanding of the spread of dengue to previously uninfected regions (including Europe in the context of globalization and climate change.The consortium comprises 12 work packages to address a set of research questions in three areas: Research area 1: Develop a comprehensive early warning and surveillance system that has predictive capability for epidemic dengue and benefits from novel tools for laboratory diagnosis and vector monitoring. Research area 2: Develop novel strategies to prevent dengue in children. Research area 3: Understand and predict the risk of global spread of dengue, in particular the risk of introduction and establishment in Europe, within the context of parameters of vectorial capacity, global mobility, and climate change.In this paper, we report on the rationale and specific study objectives of ‘DengueTools’. DengueTools is funded under the Health theme of the Seventh Framework Programme of the European Community, Grant

  6. The advancement of electric vehicles - case: Tesla Motors. Disruptive technology requiring systemic innovating

    OpenAIRE

    Lehtinen, Petri

    2015-01-01

    Electric vehicles have existed for over 100 years as a disruptive innovation. Even though they have always been easier to use, quieter and cleaner, gasoline cars have beaten it in price, range and faster fueling. As gasoline cars have been the technological standard for the past 150 years there has been no motivation by car manufacturers to advance electric vehicles. By producing electric vehicles Tesla Motors has appropriately become the first successful startup car manufacturer in over 100 ...

  7. Lessons learned from the tokamak Advanced Reactor Innovation and Evaluation Study (ARIES)

    International Nuclear Information System (INIS)

    Krakowski, R.A.; Bathke, C.G.; Miller, R.L.; Werley, K.A.

    1994-01-01

    Lessons from the four-year ARIES (Advanced Reactor Innovation and Evaluation Study) investigation of a number of commercial magnetic-fusion-energy (MFE) power-plant embodiments of the tokamak are summarized. These lessons apply to physics, engineering and technology, and environmental, safety, and health (ES ampersand H) characteristics of projected tokamak power plants. Summarized herein are the composite conclusions and lessons developed in the course of four conceptual tokamak power-plant designs. A general conclusion from this extensive investigation of the commercial potential of tokamak power plants is the need for combined, symbiotic advances in both physics, engineering, and materials before economic competitiveness with developing advanced energy sources can be realized. Advances in materials are also needed for the exploitation of environmental advantages otherwise inherent in fusion power

  8. Lessons learned from the Tokamak Advanced Reactor Innovation and Evaluation Study (ARIES)

    International Nuclear Information System (INIS)

    Krakowski, R.A.; Bathke, C.G.; Miller, R.L.; Werley, K.A.

    1994-01-01

    Lessons from the four-year ARIES (Advanced Reactor Innovation and Evaluation Study) investigation of a number of commercial magnetic-fusion-energy (MFE) power-plant embodiments of the tokamak are summarized. These lessons apply to physics, engineering and technology, and environmental, safety and health (ES ampersand H) characteristics of projected tokamak power plants. A general conclusion from this extensive investigation of the commercial potential of tokamak power plants is the need for combined, symbiotic advances relative to present understanding in physics, engineering, and materials before economic competitiveness with developing advanced energy sources can be realized. Advanced tokamak plasmas configured in the second-stability regime that achieve both high β and bootstrap fractions near unity through strong profile control offer high promise in this regard

  9. Innovative grinding wheel design for cost-effective machining of advanced ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Licht, R.H.; Kuo, P.; Liu, S.; Murphy, D.; Picone, J.W.; Ramanath, S.

    2000-05-01

    This Final Report covers the Phase II Innovative Grinding Wheel (IGW) program in which Norton Company successfully developed a novel grinding wheel for cost-effective cylindrical grinding of advanced ceramics. In 1995, Norton Company successfully completed the 16-month Phase I technical effort to define requirements, design, develop, and evaluate a next-generation grinding wheel for cost-effective cylindrical grinding of advanced ceramics using small prototype wheels. The Phase II program was initiated to scale-up the new superabrasive wheel specification to larger diameters, 305-mm to 406-mm, required for most production grinding of cylindrical ceramic parts, and to perform in-house and independent validation grinding tests.

  10. TOWARDS INNOVATIVE GEOSPATIAL TOOLS FOR FIT-FOR-PURPOSE LAND RIGHTS MAPPING

    Directory of Open Access Journals (Sweden)

    M. Koeva

    2017-09-01

    Full Text Available In large parts of sub Saharan Africa it remains an ongoing challenging to map millions of unrecognized land rights. Existing approaches for recognizing these rights have proven inappropriate in many cases. A new generation of tools needs to be developed to support faster, cheaper, easier, and more responsible land rights mapping. This is the main goal of its4land, an European Commission Horizon 2020 project that aims to develop innovative tools inspired by the continuum of land rights, fit-for-purpose land administration, and cadastral intelligence. its4land is using strategic collaboration between the EU and East Africa to deliver innovative, scalable, and transferrable ICT solutions. The innovation process incorporates a broad range of stakeholders and emergent geospatial technologies, including smart sketchmaps, UAVs, automated feature extraction, as well as geocloud services. The aim is to combine innovative technologies, capture the specific needs, market opportunities and readiness of end-users in the domain of land tenure information recording in Eastern Africa. The project consists of a four year work plan, € 3.9M funding, and eight consortium partners collaborating with stakeholders from six case study locations in Ethiopia, Kenya, and Rwanda. The major tasks include tool development, prototyping, and demonstration for local, national, regional, and international interest groups. The case locations cover different land uses such as: urban, peri-urban, rural smallholder, and (former pastoralist. This paper describes the project’s activities within the first 18 months and covers barriers discovered, lessons learned and results achieved.

  11. Innovated Conceptual Design of Loading Unloading Tool for Livestock at the Port

    Science.gov (United States)

    Mustakim, Achmad; Hadi, Firmanto

    2018-03-01

    The condition of loading and unloading process of livestock in a number of Indonesian ports doesn’t meet the principle of animal welfare, which makes cattle lose weight and injury when unloaded. Livestock loading and unloading is done by throwing cattle into the sea one by one, tying cattle hung with a sling strap and push the cattle to the berth directly. This process is against PP. 82 year 2000 on Article 47 and 55 about animal welfare. Innovation of loading and unloading tools design offered are loading and unloading design with garbarata. In the design of loading and unloading tools with garbarata, apply the concept of semi-horizontal hydraulic ladder that connects the ship and truck directly. This livestock unloading equipment design innovation is a combination of fire extinguisher truck design and bridge equipped with weightlifting equipment. In 10 years of planning garbarata, requires a total cost of IDR 321,142,921; gets benefits IDR 923,352,333; and BCR (Benefit-Cost Ratio) Value worth 2.88. BCR value >1 means the tool is feasible applied. The designs of this loading and unloading tools are estimated up to 1 hour faster than existing way. It can also minimize risks such as injury and also weight reduction livestock agencies significantly.

  12. Ultrafast Bessel beams: advanced tools for laser materials processing

    Science.gov (United States)

    Stoian, Razvan; Bhuyan, Manoj K.; Zhang, Guodong; Cheng, Guanghua; Meyer, Remy; Courvoisier, Francois

    2018-05-01

    Ultrafast Bessel beams demonstrate a significant capacity of structuring transparent materials with a high degree of accuracy and exceptional aspect ratio. The ability to localize energy on the nanometer scale (bypassing the 100-nm milestone) makes them ideal tools for advanced laser nanoscale processing on surfaces and in the bulk. This allows to generate and combine micron and nano-sized features into hybrid structures that show novel functionalities. Their high aspect ratio and the accurate location can equally drive an efficient material modification and processing strategy on large dimensions. We review, here, the main concepts of generating and using Bessel non-diffractive beams and their remarkable features, discuss general characteristics of their interaction with matter in ablation and material modification regimes, and advocate their use for obtaining hybrid micro and nanoscale structures in two and three dimensions (2D and 3D) performing complex functions. High-throughput applications are indicated. The example list ranges from surface nanostructuring and laser cutting to ultrafast laser welding and the fabrication of 3D photonic systems embedded in the volume.

  13. Functional toxicology: tools to advance the future of toxicity testing

    Science.gov (United States)

    Gaytán, Brandon D.; Vulpe, Chris D.

    2014-01-01

    The increased presence of chemical contaminants in the environment is an undeniable concern to human health and ecosystems. Historically, by relying heavily upon costly and laborious animal-based toxicity assays, the field of toxicology has often neglected examinations of the cellular and molecular mechanisms of toxicity for the majority of compounds—information that, if available, would strengthen risk assessment analyses. Functional toxicology, where cells or organisms with gene deletions or depleted proteins are used to assess genetic requirements for chemical tolerance, can advance the field of toxicity testing by contributing data regarding chemical mechanisms of toxicity. Functional toxicology can be accomplished using available genetic tools in yeasts, other fungi and bacteria, and eukaryotes of increased complexity, including zebrafish, fruit flies, rodents, and human cell lines. Underscored is the value of using less complex systems such as yeasts to direct further studies in more complex systems such as human cell lines. Functional techniques can yield (1) novel insights into chemical toxicity; (2) pathways and mechanisms deserving of further study; and (3) candidate human toxicant susceptibility or resistance genes. PMID:24847352

  14. Astonishing advances in mouse genetic tools for biomedical research.

    Science.gov (United States)

    Kaczmarczyk, Lech; Jackson, Walker S

    2015-01-01

    The humble house mouse has long been a workhorse model system in biomedical research. The technology for introducing site-specific genome modifications led to Nobel Prizes for its pioneers and opened a new era of mouse genetics. However, this technology was very time-consuming and technically demanding. As a result, many investigators continued to employ easier genome manipulation methods, though resulting models can suffer from overlooked or underestimated consequences. Another breakthrough, invaluable for the molecular dissection of disease mechanisms, was the invention of high-throughput methods to measure the expression of a plethora of genes in parallel. However, the use of samples containing material from multiple cell types could obfuscate data, and thus interpretations. In this review we highlight some important issues in experimental approaches using mouse models for biomedical research. We then discuss recent technological advances in mouse genetics that are revolutionising human disease research. Mouse genomes are now easily manipulated at precise locations thanks to guided endonucleases, such as transcription activator-like effector nucleases (TALENs) or the CRISPR/Cas9 system, both also having the potential to turn the dream of human gene therapy into reality. Newly developed methods of cell type-specific isolation of transcriptomes from crude tissue homogenates, followed by detection with next generation sequencing (NGS), are vastly improving gene regulation studies. Taken together, these amazing tools simplify the creation of much more accurate mouse models of human disease, and enable the extraction of hitherto unobtainable data.

  15. Innovative methods and tools for professionals working in supported living services for intellectually disabled persons.

    Science.gov (United States)

    Gruiz, Katalin

    2015-01-01

    Autonomy of mid-seriously and seriously intellectually disabled persons is encouraged both by legislations on human rights and the modern social care and services. The process leading to the maximum possible autonomy is illustrated by a developmental spiral in our model. Specialty of the development is that the personal educational projects are realized during everyday activities. The process requires conscious professionals with an empowering and motivating attitude, with adult relationship to the intellectually disabled persons and versatile skills and tools. In this educational relationship the social professional and the supported person are equal partners moving together along the spiral of human development. An innovative tool-battery has been developed aiding support-staff in the 'pedagogical' task embedded into everyday social services. The tool-battery and its first application in supported living services of the Hungarian Down Foundation are introduced in this paper.

  16. Discover Space Weather and Sun's Superpowers: Using CCMC's innovative tools and applications

    Science.gov (United States)

    Mendoza, A. M. M.; Maddox, M. M.; Kuznetsova, M. M.; Chulaki, A.; Rastaetter, L.; Mullinix, R.; Weigand, C.; Boblitt, J.; Taktakishvili, A.; MacNeice, P. J.; Pulkkinen, A. A.; Pembroke, A. D.; Mays, M. L.; Zheng, Y.; Shim, J. S.

    2015-12-01

    Community Coordinated Modeling Center (CCMC) has developed a comprehensive set of tools and applications that are directly applicable to space weather and space science education. These tools, some of which were developed by our student interns, are capable of serving a wide range of student audiences, from middle school to postgraduate research. They include a web-based point of access to sophisticated space physics models and visualizations, and a powerful space weather information dissemination system, available on the web and as a mobile app. In this demonstration, we will use CCMC's innovative tools to engage the audience in real-time space weather analysis and forecasting and will share some of our interns' hands-on experiences while being trained as junior space weather forecasters. The main portals to CCMC's educational material are ccmc.gsfc.nasa.gov and iswa.gsfc.nasa.gov

  17. VITA-6.2: Advanced visual tool for information management

    International Nuclear Information System (INIS)

    Jacobson, Z.; Truong, Q.S.; Houston, B.; Taylor, V.; Herber, N.; El Gebaly, A.

    2007-01-01

    Visual Interface for Text Analysis (VITA), our combined user interface and meta-search engine software application, improves the quality and speed at which intelligence analysts can explore novel massive text corpora via innovations that facilitate user contextual awareness. (author)

  18. Innovators.

    Science.gov (United States)

    NEA Today, 2001

    2001-01-01

    Describes various innovations that have been developed to enhance education. These innovations include: helping educators help at-risk students succeed; promoting high school journalism; ensuring quality online learning experiences; developing a student performing group that uses theater to address social issues; and having students design their…

  19. STRING 3: An Advanced Groundwater Flow Visualization Tool

    Science.gov (United States)

    Schröder, Simon; Michel, Isabel; Biedert, Tim; Gräfe, Marius; Seidel, Torsten; König, Christoph

    2016-04-01

    The visualization of 3D groundwater flow is a challenging task. Previous versions of our software STRING [1] solely focused on intuitive visualization of complex flow scenarios for non-professional audiences. STRING, developed by Fraunhofer ITWM (Kaiserslautern, Germany) and delta h Ingenieurgesellschaft mbH (Witten, Germany), provides the necessary means for visualization of both 2D and 3D data on planar and curved surfaces. In this contribution we discuss how to extend this approach to a full 3D tool and its challenges in continuation of Michel et al. [2]. This elevates STRING from a post-production to an exploration tool for experts. In STRING moving pathlets provide an intuition of velocity and direction of both steady-state and transient flows. The visualization concept is based on the Lagrangian view of the flow. To capture every detail of the flow an advanced method for intelligent, time-dependent seeding is used building on the Finite Pointset Method (FPM) developed by Fraunhofer ITWM. Lifting our visualization approach from 2D into 3D provides many new challenges. With the implementation of a seeding strategy for 3D one of the major problems has already been solved (see Schröder et al. [3]). As pathlets only provide an overview of the velocity field other means are required for the visualization of additional flow properties. We suggest the use of Direct Volume Rendering and isosurfaces for scalar features. In this regard we were able to develop an efficient approach for combining the rendering through raytracing of the volume and regular OpenGL geometries. This is achieved through the use of Depth Peeling or A-Buffers for the rendering of transparent geometries. Animation of pathlets requires a strict boundary of the simulation domain. Hence, STRING needs to extract the boundary, even from unstructured data, if it is not provided. In 3D we additionally need a good visualization of the boundary itself. For this the silhouette based on the angle of

  20. Advanced Fuel Cycle Economic Tools, Algorithms, and Methodologies

    Energy Technology Data Exchange (ETDEWEB)

    David E. Shropshire

    2009-05-01

    The Advanced Fuel Cycle Initiative (AFCI) Systems Analysis supports engineering economic analyses and trade-studies, and requires a requisite reference cost basis to support adequate analysis rigor. In this regard, the AFCI program has created a reference set of economic documentation. The documentation consists of the “Advanced Fuel Cycle (AFC) Cost Basis” report (Shropshire, et al. 2007), “AFCI Economic Analysis” report, and the “AFCI Economic Tools, Algorithms, and Methodologies Report.” Together, these documents provide the reference cost basis, cost modeling basis, and methodologies needed to support AFCI economic analysis. The application of the reference cost data in the cost and econometric systems analysis models will be supported by this report. These methodologies include: the energy/environment/economic evaluation of nuclear technology penetration in the energy market—domestic and internationally—and impacts on AFCI facility deployment, uranium resource modeling to inform the front-end fuel cycle costs, facility first-of-a-kind to nth-of-a-kind learning with application to deployment of AFCI facilities, cost tradeoffs to meet nuclear non-proliferation requirements, and international nuclear facility supply/demand analysis. The economic analysis will be performed using two cost models. VISION.ECON will be used to evaluate and compare costs under dynamic conditions, consistent with the cases and analysis performed by the AFCI Systems Analysis team. Generation IV Excel Calculations of Nuclear Systems (G4-ECONS) will provide static (snapshot-in-time) cost analysis and will provide a check on the dynamic results. In future analysis, additional AFCI measures may be developed to show the value of AFCI in closing the fuel cycle. Comparisons can show AFCI in terms of reduced global proliferation (e.g., reduction in enrichment), greater sustainability through preservation of a natural resource (e.g., reduction in uranium ore depletion), value from

  1. Progress in LHCD: a tool for advanced regimes on ITER

    Energy Technology Data Exchange (ETDEWEB)

    Tuccillo, A. A.

    2005-07-01

    Since the early 80s, Lower Hybrid (LH) waves have driven plasma current non-inductively in tokamak experiments with efficiency far higher than other auxiliary systems, especially at low plasma temperature. The latter aspect makes LH the natural candidate for off axis current drive (CD) in ITER where current profile control will be required to maintain burning performance on a long time scale. The difficulties in coupling LH waves in high performance H-mode plasmas led in the 90s to the decision, by the ITER JCT, of not supporting directly the development of a LH system, with subsequent exclusion of LH from ITER initial Hn and CD systems. Nevertheless, the LH activity continued in all areas: theory, experiments, modelling and R and D. Recently, in JET, the problem of coupling LH waves in severe edge conditions (ELMy plasmas and very low SOL densities) has been solved by localised gas injection. LH has then boosted the research on advanced scenarios allowing a variety of current profiles, from peaked to deeply hollow, to be used in generating Internal Transport Barriers (ITBs). In JET, long ITBs (11s) have been sustained for times close to the resistive time scale in full CD conditions, additionally pulses lasting minutes, relying on LHCD, are routinely obtained in Tore Supra. Advanced scenarios have also been obtained in conditions of dominant electron heating (FTU, Tore Supra) and efficient CD has been demonstrated at ITER relevant densities on FTU. In these experiments, an improvement of the Electron Cyclotron (EC) CD efficiency (up to 4?) due to synergy with LH is also observed both in normal operation and with EC resonating at a down shifted frequency. Modelling all these experiments has been a good test bench for LH codes and has increased the confidence in their use to predict future experiments. The use of LH as an actuator for Real Time Control of the plasma current profile has become a powerful tool to optimise ITB dynamics in JET and JT-60U. An LH system

  2. Innovative Tools for Water Quality/Quantity Management: New York City's Operations Support Tool

    Science.gov (United States)

    Wang, L.; Schaake, J. C.; Day, G. N.; Porter, J.; Sheer, D. P.; Pyke, G.

    2011-12-01

    The New York City Department of Environmental Protection (DEP) manages New York City's water supply, which is comprised of over 20 reservoirs and supplies more than 1 billion gallons of water per day to over 9 million customers. Recently, DEP has initiated design of an Operations Support Tool (OST), a state-of-the-art decision support system to provide computational and predictive support for water supply operations and planning. This presentation describes the technical structure of OST, including the underlying water supply and water quality models, data sources and database management, reservoir inflow forecasts, and the functionalities required to meet the needs of a diverse group of end users. OST is a major upgrade of DEP's current water supply - water quality model, developed to evaluate alternatives for controlling turbidity in NYC's Catskill reservoirs. While the current model relies on historical hydrologic and meteorological data, OST can be driven by forecasted future conditions. It will receive a variety of near-real-time data from a number of sources. OST will support two major types of simulations: long-term, for evaluating policy or infrastructure changes over an extended period of time; and short-term "position analysis" (PA) simulations, consisting of multiple short simulations, all starting from the same initial conditions. Typically, the starting conditions for a PA run will represent those for the current day and traces of forecasted hydrology will drive the model for the duration of the simulation period. The result of these simulations will be a distribution of future system states based on system operating rules and the range of input ensemble streamflow predictions. DEP managers will analyze the output distributions and make operation decisions using risk-based metrics such as probability of refill. Currently, in the developmental stages of OST, forecasts are based on antecedent hydrologic conditions and are statistical in nature. The

  3. State-of-the-art Report on Innovative Fuels for Advanced Nuclear Systems

    International Nuclear Information System (INIS)

    Chauvin, N.; Minato, K.; Ogata, T.; Lee, C.B.; Pouchon, M.A.; Pasamehmetoglu, K.O.; Choi, Y.J.; Kennedy, J.R.; Massara, S.; Cornet, S.; ); Sommers, J.; ); McClellan, K.

    2014-01-01

    Development of innovative fuels such as homogeneous and heterogeneous fuels, ADS fuels, and oxide, metal, nitride and carbide fuels is an important stage in the implementation process of advanced nuclear systems. Several national and international R and D programmes are investigating minor actinide-bearing fuels due to their ability to help reduce the radiotoxicity of spent fuel and therefore decrease the burden on geological repositories. Minor actinides can be converted into a suitable fuel form for irradiation in reactor systems where they are transmuted into fission products with a significantly shorter half-life. This report compares recent studies of fuels containing minor actinides for use in advanced nuclear systems. The studies review different fuels for several types of advanced reactors by examining various technical issues associated with fabrication, characterisation, irradiation performance, design and safety criteria, as well as technical maturity. (authors)

  4. Customised 3D Printing: An Innovative Training Tool for the Next Generation of Orbital Surgeons.

    Science.gov (United States)

    Scawn, Richard L; Foster, Alex; Lee, Bradford W; Kikkawa, Don O; Korn, Bobby S

    2015-01-01

    Additive manufacturing or 3D printing is the process by which three dimensional data fields are translated into real-life physical representations. 3D printers create physical printouts using heated plastics in a layered fashion resulting in a three-dimensional object. We present a technique for creating customised, inexpensive 3D orbit models for use in orbital surgical training using 3D printing technology. These models allow trainee surgeons to perform 'wet-lab' orbital decompressions and simulate upcoming surgeries on orbital models that replicate a patient's bony anatomy. We believe this represents an innovative training tool for the next generation of orbital surgeons.

  5. Lean management: innovative tools for engaging teams in continuous quality improvement.

    Science.gov (United States)

    Perreault, Lucille; Vaillancourt, Lise; Filion, Catherine; Hadj, Camélia

    2014-01-01

    Lean management has proven to be a sustainable method to ensure a high level of patient care through innovation and teamwork. It involves a set of six tools that allow for visual management shared among team members. The team focuses their efforts on the improvement of organizational indicators in a standardized and engaging way, resulting in the sustainability of improvements. This article outlines the program's rollout at Montfort Hospital (l'Hôpital Montfort). In only a few months, two pilot units accomplished close to 50 improvements each. In addition, the organizational employee satisfaction questionnaire showed very positive results. Copyright © 2014 Longwoods Publishing.

  6. The Advanced Exploration Systems Water Recovery Project: Innovation on 2 Fronts

    Science.gov (United States)

    Sarguisingh, Miriam M.; Neumeyer, Derek; Shull, Sarah

    2012-01-01

    As NASA looks forward to sending humans farther away from Earth, we will have to develop a transportation architecture that is highly reliable and that can sustain life for long durations without the benefit of Earth s proximity for continuous resupply or even operational guidance. NASA has consistently been challenged with performing great feats of innovation, but particularly in this time of economic stress, we are challenged to go farther with less. The Advanced Exploration Systems (AES) projects were implemented to address both of these needs by not only developing innovative technologies, but by incorporating innovative management styles and processes that foster the needed technical innovation given a small amount of resources. This presentation explains how the AES Water Recovery Project is exhibiting innovation on both fronts; technical and process. The AES Water Recovery Project (WRP) is actively engineering innovative technologies in order to maximize the efficiency of water recovery. The development of reliable, energy-efficient, and low-mass spacecraft systems to provide environmental control and life support (ECLS) is critical to enable long-duration human missions outside of low-Earth orbit. Recycling of life support consumables is necessary to reduce resupply mass and provide for vehicle autonomy. To address this, the WRP is working on a rotary distiller that has shown enhanced performance over the state-of-the-art (SOA). Additionally, the WRP is looking at innovative ways to address issues present in the state-of-the-art (SOA) systems pertaining to toxicity and calcium scale buildup. As an AES project, the WRP has a more streamlined Skunk Works like approach to technology development intended to reduce overhead but achieve a more refined end product. The project has incorporated key partnerships between NASA centers as well as between NASA and industry. A minimal project management style has been implemented such that risks are managed and

  7. User involvement and supporting tools in business-to-business service innovations: Insights from Facility Management services

    DEFF Research Database (Denmark)

    Nardelli, Giulia

    is the generalizability of the findings to other business-to-business service sectors. More research conducted both in FM services and other service sectors would help to shed light on the generalizability of these findings. Originality/value – The study contributes with new and detailed insights into the complexity......Purpose – This article investigates and conceptualizes user involvement in business-to-business service innovations as well as the tools that are used to support interactions in such a service innovation process. Design/methodology/approach – The paper uses a qualitative research approach to answer...... the research question. By following Miles and Huberman (1984)’s this study started with a literature review of studies investigating service innovation, service innovations models, user roles and tools in service innovation in general, to conduct an empirical investigation in facility management (FM) services...

  8. Innovation

    African Journals Online (AJOL)

    In recent years ULA has emphasized advocacy, and contributed to progress towards new legislation (freedom of information, copyright, the ... East African Community e-government strategy) of importance to the library and ... Innovation Vol.

  9. An Innovative Unmanned System for Advanced Environmental Monitoring: Design and Development

    Science.gov (United States)

    Marsella, Ennio; Giordano, Laura; Evangelista, Lorenza; Iengo, Antonio; di Filippo, Alessandro; Coppola, Aniello

    2015-04-01

    The paper summarizes the design and development of a new technology and tools for real-time coordination and control of unmanned vehicles for advanced environmental monitoring. A new Unmanned System has been developed at Institute for Coastal Marine Environmental - National Research Council (Italy), in the framework of two National Operational Programs (PON): Technological Platform for Geophysical and Environmental Marine Survey-PITAM and Integrated Systems and Technologies for Geophysical and Environmental Monitoring in coastal-marine areas-STIGEAC. In particular, the system includes one Unmanned Aerial Vehicle (UAV) and two Unmanned Marine Vehicles (UMV). Major innovations concern the implementation of a new architecture to control each drone and/or to allow the cooperation between heterogeneous vehicles, the integration of distributed sensing techniques and real-time image processing capabilities. Part of the research in these projects involves, therefore, an architecture, where the ground operator can communicate with the Unmanned Vehicles at various levels of abstraction using pointing devices and video viewing. In detail, a Ground Control Station (GCS) has been design and developed to allow the government in security of the drones within a distance up to twenty kilometers for air explorations and within ten nautical miles for marine activities. The Ground Control Station has the following features: 1. hardware / software system for the definition of the mission profiles; 3. autonomous and semi-autonomous control system by remote control (joystick or other) for the UAV and UMVs; 4. integrated control system with comprehensive visualization capabilities, monitoring and archiving of real-time data acquired from scientific payload; 5. open structure to future additions of systems, sensors and / or additional vehicles. In detail, the UAV architecture is a dual-rotor, with an endurance ranging from 55 to 200 minutes, depending on payload weight (maximum 26 kg) and

  10. TOOLS OF KNOWLEDGE DISSEMINATION WITHIN A NATIONAL DEFENSE INSTITUTION FOR INNOVATION, TECHNOLOGY AND SCIENCE

    Directory of Open Access Journals (Sweden)

    Edson Aparecida de Araújo Querido Oliveira

    2006-11-01

    Full Text Available This paper describes and analyzes in a National Defense Institution for Innovation, Technology and Science its tools of knowledge dissemination. The methodology contemplates the period of 2004 and 2005. Qualitative and quantitative information orientate the research in order to understand focal aspects on knowledge dissemination, in comparison with theoretical references of renowned authors and other elaborated research searching for elements to perform an organizational diagnosis, focused on the knowledge dissemination as well as on the forces which promote or obstruct the organizational development. Conclusions are that the tools of knowledge dissemination must suitable to spread the tacit knowledge in such a way as the explicit ones and that, in a National Defense Institution, other important aspects must be considered, a time that, being the spread knowledge of wrong form can, besides bringing damages for the organization, to compromise the national sovereignty.

  11. New tools for Content Innovation and data sharing: Enhancing reproducibility and rigor in biomechanics research.

    Science.gov (United States)

    Guilak, Farshid

    2017-03-21

    We are currently in one of the most exciting times for science and engineering as we witness unprecedented growth in our computational and experimental capabilities to generate new data and models. To facilitate data and model sharing, and to enhance reproducibility and rigor in biomechanics research, the Journal of Biomechanics has introduced a number of tools for Content Innovation to allow presentation, sharing, and archiving of methods, models, and data in our articles. The tools include an Interactive Plot Viewer, 3D Geometric Shape and Model Viewer, Virtual Microscope, Interactive MATLAB Figure Viewer, and Audioslides. Authors are highly encouraged to make use of these in upcoming journal submissions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Characterizing the intrinsic bioremediation potential of 1,4-dioxane and trichloroethene using innovative environmental diagnostic tools.

    Science.gov (United States)

    Chiang, Sheau-Yun Dora; Mora, Rebecca; Diguiseppi, William H; Davis, Greg; Sublette, Kerry; Gedalanga, Phillip; Mahendra, Shaily

    2012-09-01

    An intrinsic biodegradation study involving the design and implementation of innovative environmental diagnostic tools was conducted to evaluate whether monitored natural attenuation (MNA) could be considered as part of the remedial strategy to treat an aerobic aquifer contaminated with 1,4-dioxane and trichloroethene (TCE). In this study, advanced molecular biological and stable isotopic tools were applied to confirm in situ intrinsic biodegradation of 1,4-dioxane and TCE. Analyses of Bio-Trap® samplers and groundwater samples collected from monitoring wells verified the abundance of bacteria and enzymes capable of aerobically degrading TCE and 1,4-dioxane. Furthermore, phospholipid fatty acid analysis with stable isotope probes (PLFA-SIP) of the microbial community validated the ability for microbial degradation of TCE and 1,4-dioxane. Compound specific isotope analysis (CSIA) of groundwater samples for TCE resulted in δ(13)C values that indicated likely biodegradation of TCE in three of the four monitoring wells sampled. Results of the MNA evaluation showed that enzymes capable of aerobically degrading TCE and 1,4-dioxane were present, abundant, and active in the aquifer. Taken together, these results provide direct evidence of the occurrence of TCE and 1,4-dioxane biodegradation at the study site, supporting the selection of MNA as part of the final remedy at some point in the future.

  13. Promoting development and uptake of health innovations: The Nose to Tail Tool [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Archna Gupta

    2016-03-01

    Full Text Available Introduction Health sector management is increasingly complex as new health technologies, treatments, and innovative service delivery strategies are developed. Many of these innovations are implemented prematurely, or fail to be implemented at scale, resulting in substantial wasted resources.   Methods A scoping review was conducted to identify articles that described the scale up process conceptually or that described an instance in which a healthcare innovation was scaled up. We define scale up as the expansion and extension of delivery or access to an innovation for all end users in a jurisdiction who will benefit from it. Results Sixty nine articles were eligible for review. Frequently described stages in the innovation process and contextual issues that influence progress through each stage were mapped. 16 stages were identified: 12 deliberation and 4 action stages. Included papers suggest that innovations progress through stages of maturity and the uptake of innovation depends on the innovation aligning with the interests of 3 critical stakeholder groups (innovators, end users and the decision makers and is also influenced by 3 broader contexts (social and physical environment, the health system, and the regulatory, political and economic environment. The 16 stages form the rows of the Nose to Tail Tool (NTT grid and the 6 contingency factors form columns. The resulting stage-by-issue grid consists of 72 cells, each populated with cell-specific questions, prompts and considerations from the reviewed literature. Conclusion We offer a tool that helps stakeholders identify the stage of maturity of their innovation, helps facilitate deliberative discussions on the key considerations for each major stakeholder group and the major contextual barriers that the innovation faces. We believe the NTT will help to identify potential problems that the innovation will face and facilitates early modification, before large investments are made in a

  14. Innovation as a Tool to Make the First Years Count: I-Lab--An Innovation Approach to Unattended Social Needs

    Science.gov (United States)

    Goettsch, Marieke; Mateo Diaz, Mercedes; Canete, Nicolas

    2018-01-01

    One of the main objectives of the Inter-American Development Bank (IDB) is to improve the lives of people in the Latin America and Caribbean (LAC) region by reducing inequality. In 2008, the IDB's Division of Competitiveness, Technology and Innovation (CTI) developed the Innovation Lab (I-Lab), which falls under the umbrella of a growing set of…

  15. Innovative Practice in Advancement of Academic Nurse Educator Careers: Developing Scholarship From Program Grants.

    Science.gov (United States)

    Eddy, Linda L; Hoeksel, Renee; Fitzgerald, Cindy; Doutrich, Dawn

    We describe an innovative practice in advancing careers of academic nurse educators: demonstrating scholarly productivity from program grants. Scholarly productivity is often narrowly defined, especially in research-intensive institutions. The expectation may be a career trajectory based on the traditional scholarship of discovery. However, nurse educators, especially at the associate and full professor ranks, are often involved in leadership activities that include writing and managing program grants. We encourage the academy to value and support the development of program grants that include significant scholarly components, and we offer exemplars of associate and full professor scholarship derived from these projects.

  16. Food Safety Practices Assessment Tool: An Innovative Way to Test Food Safety Skills among Individuals with Special Needs

    Science.gov (United States)

    Carbone, Elena T.; Scarpati, Stanley E.; Pivarnik, Lori F.

    2013-01-01

    This article describes an innovative assessment tool designed to evaluate the effectiveness of a food safety skills curriculum for learners receiving special education services. As schools respond to the increased demand for training students with special needs about food safety, the need for effective curricula and tools is also increasing. A…

  17. An inquiry on managers use of decision-making tools in the core front end of the innovation process

    DEFF Research Database (Denmark)

    Appio, Francesco P.; Achiche, Sofiane; McAloone, Tim C.

    2013-01-01

    This paper focuses on the Core Front End (CFE) activities of the innovation process to say, Opportunity Identification and Opportunity Analysis. In the CFE of innovation, several tools are used to facilitate and optimise decisions. To select them, managers of the product development team have...... is chosen and how those tools impact specific performance metrics. From the analyses and hypotheses testing performed, it clearly emerges that there is no link between being aware of basic requirements (inputs/outputs) to appropriately use a certain tool and dimensions such as tools’ effectiveness...

  18. TNO-ADVANCE: a modular power train simulation and design tool

    NARCIS (Netherlands)

    Venne, J.W.C. van de; Hendriksen, P.; Smokers, R.T.M.; Verkiel, M.

    1998-01-01

    To support its activities in the field of conventional and hybrid vehicles, TNO has developed ADVANCE, a modular simulation tool for the design and evaluation of advanced power trains. In this paper the various features and the potential of ADVANCE are described and illustrated by means of two case

  19. Advanced aviation environmental modeling tools to inform policymakers

    Science.gov (United States)

    2012-08-19

    Aviation environmental models which conform to international guidance have advanced : over the past several decades. Enhancements to algorithms and databases have increasingly : shown these models to compare well with gold standard measured data. The...

  20. Reactor physics innovations of the advanced CANDU reactor core: adaptable and efficient

    International Nuclear Information System (INIS)

    Chan, P.S.W.; Hopwood, J.M.; Bonechi, M.

    2003-01-01

    The Advanced CANDU Reactor (ACR) is designed to have a benign, operator-friendly core physics characteristic, including a slightly negative coolant-void reactivity and a moderately negative power coefficient. The discharge fuel burnup is about three times that of natural uranium fuel in current CANDU reactors. Key features of the reactor physics innovations in the ACR core include the use of H 2 O coolant, slightly enriched uranium (SEU) fuel, and D 2 O moderator in a reduced lattice pitch. These innovations result in substantial improvements in economics, as well as significant enhancements in reactor performance and waste reduction over the current reactor design. The ACR can be readily adapted to different power outputs by increasing or decreasing the number of fuel channels, while maintaining identical fuel and fuel-channel characteristics. The flexibility provided by on-power refuelling and simple fuel bundle design enables the ACR to easily adapt to the use of plutonium and thorium fuel cycles. No major modifications to the basic ACR design are required because the benign neutronic characteristics of the SEU fuel cycle are also inherent in these advanced fuel cycles. (author)

  1. Innovation

    African Journals Online (AJOL)

    The purpose of Innovation journal of appropriate librarianship and information work in Southern Africa is to publish material on libraries, information supply and other related matters in South and Southern Africa. Vol 45 (2012). DOWNLOAD FULL TEXT Open Access DOWNLOAD FULL TEXT Subscription or Fee Access ...

  2. Innovation

    DEFF Research Database (Denmark)

    Torfing, Jacob; Ricard, Lykke Margot

    2017-01-01

    Innovation i krydsfeltet mellem forskellige styringsparadigmer i offentlige organisationer. New Public Governance gør det muligt at skabe offentlig værdi på nye måder. Men NPG er ingen trylledrik, der fra den ene dag til den anden skaber balance mellem borgernes store forventninger og en trængt ø...

  3. TCAD tool for innovative MEMS and MOEMS: an all-in-one solution

    Science.gov (United States)

    Triltsch, U.; Büttgenbach, S.

    2008-02-01

    In this paper we present a TCAD tool for MEMS, which combines process and layout design and provides links to behavioral modeling tools as well as to specialized modules for the optimized design of single components. There is a large amount of new fabrication technologies available which make the design of highly innovative MEMS and MOEMS possible. The design of such systems not only incorporates the layout of masks but also involves the composition of a flawless process chain. TCAD tools for MEMS available today do mostly not support the design of new fabrication processes together with behavioral simulation and layout design. Therefore, there is a need for a methodical approach to component-design, which leads an engineer from single components to a system ready for fabrication. Based on a conceptual model for the design process the latest version of the modular software environment BICEP 3S (Braunschweigs Integrated CAD-Environment for Product Planning Process Simulation) is explained. The concept and data model of building blocks on component level, that act as knowledge containers for fabrication ready functional elements of microsystems, are shown in detail. As the detailed simulation of single process steps is crucial in fabrication oriented design cycles, we present an atomistic etch-simulator as one example for specialized simulation modules of our design environment.

  4. Semer: a simple calculational tool for the economic evaluations of reactor systems and associated innovations

    Energy Technology Data Exchange (ETDEWEB)

    Nisan, S. [CEA Cadarache, Nuclear Reactor Directorate, DRN, Dept. of Reactor Studies, DER, Reactor and Innovative Systems Service, SERSI, 13 - Saint Paul lez Durance (France); Rouyer, J.L. [Electricite de France (EDF), Pole Industrie, Div. Ingenierie et Services, 93 - Saint-Denis (France)

    2001-07-01

    This paper summarises part of our on-going investigations on the economic evaluations of various nuclear and fossil energy systems and related innovations. These investigations are principally concerned with the development of the code system SEMER and its validation. SEMER has been developed to furnish top management and project leaders a simple tool for cost evaluations enabling a choice between competitive technological options. The cost evaluation models, actually integrated in the SEMER system, already cover a very wide range of electricity producing systems and, where relevant, their associated fuel cycles: The ''global models'', allowing rapid but relatively approximate overall cost estimations (about 15 % error). These include: Almost all the electricity producing systems using fossil energies (Oil, Coal, Gas, including gas turbines with combined cycles); Nuclear reactor systems including all the French PWRs, HTRs, Compact PWRs, and PWRs for nuclear propulsion systems. (author)

  5. Semer: a simple calculational tool for the economic evaluations of reactor systems and associated innovations

    International Nuclear Information System (INIS)

    Nisan, S.; Rouyer, J.L.

    2001-01-01

    This paper summarises part of our on-going investigations on the economic evaluations of various nuclear and fossil energy systems and related innovations. These investigations are principally concerned with the development of the code system SEMER and its validation. SEMER has been developed to furnish top management and project leaders a simple tool for cost evaluations enabling a choice between competitive technological options. The cost evaluation models, actually integrated in the SEMER system, already cover a very wide range of electricity producing systems and, where relevant, their associated fuel cycles: The ''global models'', allowing rapid but relatively approximate overall cost estimations (about 15 % error). These include: Almost all the electricity producing systems using fossil energies (Oil, Coal, Gas, including gas turbines with combined cycles); Nuclear reactor systems including all the French PWRs, HTRs, Compact PWRs, and PWRs for nuclear propulsion systems. (author)

  6. Combinatorial hexapeptide ligand libraries (ProteoMiner): an innovative fractionation tool for differential quantitative clinical proteomics.

    Science.gov (United States)

    Hartwig, Sonja; Czibere, Akos; Kotzka, Jorg; Passlack, Waltraud; Haas, Rainer; Eckel, Jürgen; Lehr, Stefan

    2009-07-01

    Blood serum samples are the major source for clinical proteomics approaches, which aim to identify diagnostically relevant or treatment-response related proteins. But, the presence of very high-abundance proteins and the enormous dynamic range of protein distribution hinders whole serum analysis. An innovative tool to overcome these limitations, utilizes combinatorial hexapeptide ligand libraries (ProteoMiner). Here, we demonstrate that ProteoMiner can be used for comparative and quantitative analysis of complex proteomes. We spiked serum samples with increasing amounts (3 microg to 300 microg) of whole E. coli lysate, processed it with ProteoMiner and performed quantitative analyses of 2D-gels. We found, that the concentration of the spiked bacteria proteome, reflected by the maintained proportional spot intensities, was not altered by ProteoMiner treatment. Therefore, we conclude that the ProteoMiner technology can be used for quantitative analysis of low abundant proteins in complex biological samples.

  7. Innovations in resource efficiency and quality management as a tool for balanced development of flour mills

    Directory of Open Access Journals (Sweden)

    A. V. Bogomolov

    2017-01-01

    Full Text Available The article considers innovative tools used in flour mills and offers management solutions aimed at increasing the competitiveness of these enterprises. The relevance of the research topic is due to the need to expand the share of the industry market through the production of domestic products based on effective quality management. Studies have shown that most mills of modern foreign flour producers are equipped with the equipment necessary to enrich the product obtained. At present, enterprises of the Altai Territory, Kemerovo, Tomsk, Ryazan and Leningrad Regions, as well as Bashkiria and Tatarstan, are engaged in flour enrichment in Russia. Calculations confirm that flour fortification not only represents a number of advantages for human health, but also is economically beneficial for industry enterprises. The introduction of concentrates into flour may lead to a slight increase in cost, but should not cause significant changes in the selling price of the final product. These technological changes will allow the flour mill to use new competitive opportunities. Improving the quality of products due to the restoration of the level of vitamins and the increase of nutritional value will attract an additional consumer. The author developed an economic-mathematical model for optimizing the structure of production and sales of products using modern components based on the example of the flour-grinding enterprise of the Belgorod region. The calculations made allowed to ensure the maximum economic effect in the conditions of maintaining the existing system of distribution of products through the distribution channels, as well as maintaining the invariance of its value with the existing volumes of production. From this it follows that innovations in systems of resource efficiency and quality management are an effective tool for the balanced development of flour milling enterprises.

  8. Innovation

    OpenAIRE

    2012-01-01

    Présenté par FutuRIS, plate-forme prospective sur la recherche, l’innovation et la société animée par l’Association Nationale de la Recherche et de la Technologie, ce volume livre un panorama du système français de recherche et d’innovation dans son environnement européen. Sont abordés dans une première partie les champs décisionnels concernés, les politiques nationales menées en matière de R&D, les relations entre enseignement supérieur et recherche et l’Espace européen de la recherche à l’h...

  9. INNOVATION

    DEFF Research Database (Denmark)

    Helms, Niels Henrik

    2012-01-01

    Kravet om innovation og kreativitet er på flere måder en stor og en ny udfordring for voksenuddannelserne. Det udfordrer det didaktiske dilemma, det at vi skal gøres til kompetente og frie mennesker gennem pædagogiske handlinger, som netop pålægger os en ufrihed. – Men hvor denne ufrihed tidligere...... kunne begrundes med, at skolen eller uddannelsen vidste bedre, så er det ikke længere tilfældet. Skolen skal sørge for, at vi lærer noget – og ikke noget andet. Men det kan ikke længere med bestemthed afgøres, hvad det er vi skal lære i skolen, fordi det nye, det kreative og ikke mindst innovative...

  10. Desktop Publishing: A Powerful Tool for Advanced Composition Courses.

    Science.gov (United States)

    Sullivan, Patricia

    1988-01-01

    Examines the advantages of using desktop publishing in advanced writing classes. Explains how desktop publishing can spur creativity, call attention to the interaction between words and pictures, encourage the social dimensions of computing and composing, and provide students with practical skills. (MM)

  11. Micro gravity - an important tool for development of advanced materials

    International Nuclear Information System (INIS)

    Sadiq, S.

    1995-01-01

    Microgravity provides the researchers the opportunity to investigate and improve the methods of creating advanced materials on earth. This can in turn assist in the advanced of economically significant technologies and technology infusement into the private sector. In some unique cases, involving inherently expensive materials that must have high purity, such as composites, high grade alloys etc. small amounts be made in space commercially and viably. A number of developed countries have gained sufficient expertise in material processing and other experiments under microgravity conditions, and their progress has been quite tremendous in this vital area of space research. The four important modes of platform, i.e., space shuttle/satellite, rocket flights, aircraft and drop tower tests have been employed for this purpose. Processing of materials in all such cases differs from the point of view of its cost effectiveness, time required to perform the expertise, instrumentation set up etc. In region of Far East and South East Asia, only one or two countries have made some advances in material processing experiments under microgravity conditions both in the upper atmosphere as well as using Drop Tower Test, but limited experimental means have made these countries to strive in this research area compared to work done in author advanced countries. The paper describes a brief history of microgravity experiments, their types and mode of transport employed for processing of novel materials under extreme low gravity or zero gravity conditions. This will definitely be useful and beneficial to developing nations of this region have entered an era of sophisticated and advanced materials processing and its utilization for industries such as aerospace, nuclear power plants, strategic materials, electronics, biological communication etc. (author)

  12. Lessons from an innovation-leader and tools to learn them

    Directory of Open Access Journals (Sweden)

    Bill Williams

    2014-09-01

    Full Text Available Purpose: A number of recent reports have suggested that communication and management skills are important competences for engineers today and are likely to continue so in the future.  While participation in strategy management decisions is expected to be important for engineers in technology driven firms, little attention is given to strategy management tools in many undergraduate engineering courses. The paper demonstrates one approach to tackling this issue. Design/methodology/approach: The authors initially present a critique of the use of standard strategy management tools SWOT analysis and Porter’s 5 Forces for decision making about future company policy. This critique is then complemented by a case-study of a university start-up, a recognized innovation-leader, in which SWOT analysis, Porter’s 5 Forces and PESTLE analysis are applied retrospectively as sense-making constructs to understand the firm’s previous policy decisions. Findings and Originality/value: The paper illustrates the potential of retrospective use of strategy management tools is demonstrated. Research limitations/implications: An obstacle confronting researchers in studies of this type is that for reasons of confidentiality it is difficult to gain access to current objective data on the financial situation and policy decisions of a firm. Furthermore this work presents a single case study. Both limitations are addressed in the appropriate section of the article. Originality/value: The value of the retrospective use of strategy management tools is illustrated.  The paper makes proposals regarding how such data can be employed in role-play activities in preparing engineers to develop interdisciplinary communication skills in the context of strategy management decision making

  13. Advanced Vibration Analysis Tool Developed for Robust Engine Rotor Designs

    Science.gov (United States)

    Min, James B.

    2005-01-01

    The primary objective of this research program is to develop vibration analysis tools, design tools, and design strategies to significantly improve the safety and robustness of turbine engine rotors. Bladed disks in turbine engines always feature small, random blade-to-blade differences, or mistuning. Mistuning can lead to a dramatic increase in blade forced-response amplitudes and stresses. Ultimately, this results in high-cycle fatigue, which is a major safety and cost concern. In this research program, the necessary steps will be taken to transform a state-of-the-art vibration analysis tool, the Turbo- Reduce forced-response prediction code, into an effective design tool by enhancing and extending the underlying modeling and analysis methods. Furthermore, novel techniques will be developed to assess the safety of a given design. In particular, a procedure will be established for using natural-frequency curve veerings to identify ranges of operating conditions (rotational speeds and engine orders) in which there is a great risk that the rotor blades will suffer high stresses. This work also will aid statistical studies of the forced response by reducing the necessary number of simulations. Finally, new strategies for improving the design of rotors will be pursued.

  14. ADVANCED AND RAPID DEVELOPMENT OF DYNAMIC ANALYSIS TOOLS FOR JAVA

    Directory of Open Access Journals (Sweden)

    Alex Villazón

    2012-01-01

    Full Text Available Low-level bytecode instrumentation techniques are widely used in many software-engineering tools for the Java Virtual Machine (JVM, that perform some form of dynamic program analysis, such as profilers or debuggers. While program manipulation at the bytecode level is very flexible, because the possible bytecode transformations are not restricted, tool development based on this technique is tedious and error-prone. As a promising alternative, the specification of bytecode instrumentation at a higher level using aspect-oriented programming (AOP can reduce tool development time and cost. Unfortunately, prevailing AOP frameworks lack some features that are essential for certain dynamic analyses. In this article, we focus on three common shortcomings in AOP frameworks with respect to the development of aspect-based tools - (1 the lack of mechanisms for passing data between woven advices in local variables, (2 the support for user-defined static analyses at weaving time, and (3 the absence of pointcuts at the level of individual basic blocks of code. We propose @J, an annotation-based AOP language and weaver that integrates support for these three features. The benefits of the proposed features are illustrated with concrete examples.

  15. Human Factors Evaluation of Advanced Electric Power Grid Visualization Tools

    Energy Technology Data Exchange (ETDEWEB)

    Greitzer, Frank L.; Dauenhauer, Peter M.; Wierks, Tamara G.; Podmore, Robin

    2009-04-01

    This report describes initial human factors evaluation of four visualization tools (Graphical Contingency Analysis, Force Directed Graphs, Phasor State Estimator and Mode Meter/ Mode Shapes) developed by PNNL, and proposed test plans that may be implemented to evaluate their utility in scenario-based experiments.

  16. Advanced Tools for Smartphone-Based Experiments: Phyphox

    Science.gov (United States)

    Staacks, S.; Hütz, S.; Stampfer, C.; Heinke, H.

    2018-01-01

    The sensors in modern smartphones are a promising and cost-effective tool for experimentation in physics education, but many experiments face practical problems. Often the phone is inaccessible during the experiment and the data usually needs to be analyzed subsequently on a computer. We address both problems by introducing a new app, called…

  17. Toward an evidence-based system for innovation support for implementing innovations with quality: tools, training, technical assistance, and quality assurance/quality improvement.

    Science.gov (United States)

    Wandersman, Abraham; Chien, Victoria H; Katz, Jason

    2012-12-01

    An individual or organization that sets out to implement an innovation (e.g., a new technology, program, or policy) generally requires support. In the Interactive Systems Framework for Dissemination and Implementation, a Support System should work with Delivery Systems (national, state and/or local entities such as health and human service organizations, community-based organizations, schools) to enhance their capacity for quality implementation of innovations. The literature on the Support System [corrected] has been underresearched and under-developedThis article begins to conceptualize theory, research, and action for an evidence-based system for innovation support (EBSIS). EBSIS describes key priorities for strengthening the science and practice of support. The major goal of EBSIS is to enhance the research and practice of support in order to build capacity in the Delivery System for implementing innovations with quality, and thereby, help the Delivery System achieve outcomes. EBSIS is guided by a logic model that includes four key support components: tools, training, technical assistance, and quality assurance/quality improvement. EBSIS uses the Getting To Outcomes approach to accountability to aid the identification and synthesis of concepts, tools, and evidence for support. We conclude with some discussion of the current status of EBSIS and possible next steps, including the development of collaborative researcher-practitioner-funder-consumer partnerships to accelerate accumulation of knowledge on the Support System.

  18. Advances in analytical tools for high throughput strain engineering

    DEFF Research Database (Denmark)

    Marcellin, Esteban; Nielsen, Lars Keld

    2018-01-01

    The emergence of inexpensive, base-perfect genome editing is revolutionising biology. Modern industrial biotechnology exploits the advances in genome editing in combination with automation, analytics and data integration to build high-throughput automated strain engineering pipelines also known...... as biofoundries. Biofoundries replace the slow and inconsistent artisanal processes used to build microbial cell factories with an automated design–build–test cycle, considerably reducing the time needed to deliver commercially viable strains. Testing and hence learning remains relatively shallow, but recent...... advances in analytical chemistry promise to increase the depth of characterization possible. Analytics combined with models of cellular physiology in automated systems biology pipelines should enable deeper learning and hence a steeper pitch of the learning cycle. This review explores the progress...

  19. Comparison of simplified and advanced building simulation tool with measured data

    DEFF Research Database (Denmark)

    Christensen, Jørgen Erik; Schiønning, Peder; Dethlefsen, Espen

    2013-01-01

    In the future building design must progress to a format where CO 2 neutral societies are optimized as a whole and innovative technologies integrated. The purpose of this paper is to demonstrate the problems using a simplified design tool to simulate a complicated building and how this may not give...

  20. Control Systems with Saturating Inputs Analysis Tools and Advanced Design

    CERN Document Server

    Corradini, Maria Letizia; Giannoni, Fabio; Orlando, Giuseppe

    2012-01-01

    This series aims to report new developments in the fields of control and information sciences - quickly, informally and at a high level. The type of material considered for publication includes: 1. Preliminary drafts of monographs and advanced textbooks 2. Lectures on a new field, or presenting a new angle on a classical field 3. Research reports 4. Reports of meetings, provided they are a) of exceptional interest and b) devoted to a specific topic. The timeliness of subject material is very important.

  1. A Review of Innovation Systems Framework as a Tool for Gendering Agricultural Innovations: Exploring Gender Learning and System Empowerment

    Science.gov (United States)

    Kingiri, Ann N.

    2013-01-01

    Purpose: To reflect on the opportunities that a systems understanding of innovation provides for addressing gender issues relevant to women, and to provide some insight on how these might be tackled. Approach: Review of literature relating to gender issues and how they relate to achieving, on the one hand, equity and efficiency goals, and on the…

  2. CAPACITY BUILDING OF TEACHERS THROUGH DISTANCE MODE USING TELECONFERENCEING AS AN INNOVATIVE TOOL

    Directory of Open Access Journals (Sweden)

    Manas RANJAN PANIGRAHI

    2012-04-01

    Full Text Available Sarva Shiksha Abhiyan (SSA is a national programme to the goals of Universalization of Elementary Education in India. Distance Education Programme (DEP plays a major role in providing technical support to the states in building capacity among institutions and people at national, state, district and sub-district levels to design, develop, produce and deliver distance learning inputs and materials in a recurrent manner. Rajasthan Council of Primary Education, Jaipur and DEP-SSA, IGNOU, New Delhi has organized 07 content based teleconferences during the period January, 2005 to October, 2005 for the capacity building of elementary school teachers. The main Objective of the study was to find out the effectiveness of the capacity building of teachers through distance mode using teleconferencing as an innovative tool. Method: the researcher was used survey method under descriptive research for investigating the impact of teleconference programmes organized on different topics and areas. Sample: The sample consists of 4775 elementary school teachers as participants from the different learning ends of the Rajasthan were selected for the study. Tools: The DEP-SSA, IGNOU developed structured opinionnaire/feedback format to know the effectiveness of teleconference programme. Data analysis: The collected data were tabulated and analyzed with the percentage techniques and it is presented in table. Finding: Most of the teacher respondents agreed on the positive contribution of teleconferencing towards capacity building of teachers.

  3. Innovations and advances in computing, informatics, systems sciences, networking and engineering

    CERN Document Server

    Elleithy, Khaled

    2015-01-01

    Innovations and Advances in Computing, Informatics, Systems Sciences, Networking and Engineering  This book includes a set of rigorously reviewed world-class manuscripts addressing and detailing state-of-the-art research projects in the areas of Computer Science, Informatics, and Systems Sciences, and Engineering. It includes selected papers from the conference proceedings of the Eighth and some selected papers of the Ninth International Joint Conferences on Computer, Information, and Systems Sciences, and Engineering (CISSE 2012 & CISSE 2013). Coverage includes topics in: Industrial Electronics, Technology & Automation, Telecommunications and Networking, Systems, Computing Sciences and Software Engineering, Engineering Education, Instructional Technology, Assessment, and E-learning.  ·       Provides the latest in a series of books growing out of the International Joint Conferences on Computer, Information, and Systems Sciences, and Engineering; ·       Includes chapters in the most a...

  4. Advanced tools for smartphone-based experiments: phyphox

    OpenAIRE

    Staacks, Sebastian; Hütz, Simon; Heinke, Heidrun; Stampfer, Christoph

    2018-01-01

    The sensors in modern smartphones are a promising and cost-effective tool for experimentation in physics education, but many experiments face practical problems. Often the phone is inaccessible during the experiment and the data usually needs to be analyzed subsequently on a computer. We address both problems by introducing a new app, called "phyphox", which is specifically designed for utilizing experiments in physics teaching. The app is free and designed to offer the same set of features o...

  5. State of an innovation system: theoretical and empirical advance towards an innovation efficiency index. Or: Walking between ridicule and praise: measuring innovation systems effieciency with a single indicator

    NARCIS (Netherlands)

    Montalvo Corral, C.; Mohammadian Moghayer, S.

    2011-01-01

    Innovation is currently seen as a cornerstone not only for economic development but also as an intrinsic human activity that could help to face the great challenges of human kind. Given the importance of innovation in the new European 2020 Strategy, measuring progress but also monitoring what drives

  6. Advances in diamond tools for working lithoid materials

    International Nuclear Information System (INIS)

    Rosso, M.; Ugues, D.; Valle, A.

    2001-01-01

    Lithoid material is a general definition to indicate a wide category of ornamental materials: they can be divided into natural (i.e. granite) or artificial (i.e. conglomerates and ceramics). All the lithoid materials are subjected to surface machining operations in order to obtain final work piece ready to be introduced an the market in form of slabs or tiles. This paper deals with the attempts of producing a machining diamond tools using a sintered steel binder. The opportunity of using a steel binder has been already highly studied by diamond tools industry, but with not satisfying outcomes and not longer developed, basically due to the catalysis action of iron and to the diamond degradation mechanism provided by high processing temperature. The binding matrix was produced by infiltration sintering. Infiltration requires the pore structure to be open and interconnected; thus, the sintered solid skeleton must have an at least 10 % porosity. Therefore, the infiltration sintering of the steel skeleton uses a temperature lower than the usually required for steel sintering one. Using the suitable infiltration agent will result in low infiltration temperature levels too (1). This should give the opportunity to work with a steel binder for diamond dispersed machining tools, without causing excessive damages to the diamond mechanical properties. The paper aims at overcoming the diamond degradation by lowering the production temperature using a definitively controlled infiltration sintering process. (author)

  7. The OGC Innovation Program Testbeds - Advancing Architectures for Earth and Systems

    Science.gov (United States)

    Bermudez, L. E.; Percivall, G.; Simonis, I.; Serich, S.

    2017-12-01

    The OGC Innovation Program provides a collaborative agile process for solving challenging science problems and advancing new technologies. Since 1999, 100 initiatives have taken place, from multi-million dollar testbeds to small interoperability experiments. During these initiatives, sponsors and technology implementers (including academia and private sector) come together to solve problems, produce prototypes, develop demonstrations, provide best practices, and advance the future of standards. This presentation will provide the latest system architectures that can be used for Earth and space systems as a result of the OGC Testbed 13, including the following components: Elastic cloud autoscaler for Earth Observations (EO) using a WPS in an ESGF hybrid climate data research platform. Accessibility of climate data for the scientist and non-scientist users via on demand models wrapped in WPS. Standards descriptions for containerize applications to discover processes on the cloud, including using linked data, a WPS extension for hybrid clouds and linking to hybrid big data stores. OpenID and OAuth to secure OGC Services with built-in Attribute Based Access Control (ABAC) infrastructures leveraging GeoDRM patterns. Publishing and access of vector tiles, including use of compression and attribute options reusing patterns from WMS, WMTS and WFS. Servers providing 3D Tiles and streaming of data, including Indexed 3d Scene Layer (I3S), CityGML and Common DataBase (CDB). Asynchronous Services with advanced pushed notifications strategies, with a filter language instead of simple topic subscriptions, that can be use across OGC services. Testbed 14 will continue advancing topics like Big Data, security, and streaming, as well as making easier to use OGC services (e.g. RESTful APIs). The Call for Participation will be issued in December and responses are due on mid January 2018.

  8. Tools of the trade introduction to advanced mathematics

    CERN Document Server

    Sally, Jr, Paul J

    2008-01-01

    This book provides a transition from the formula-full aspects of the beginning study of college level mathematics to the rich and creative world of more advanced topics. It is designed to assist the student in mastering the techniques of analysis and proof that are required to do mathematics. Along with the standard material such as linear algebra, construction of the real numbers via Cauchy sequences, metric spaces and complete metric spaces, there are three projects at the end of each chapter that form an integral part of the text. These projects include a detailed discussion of topics such

  9. Advanced impedance matching system for ICRF heating using innovative twin stub tuner and frequency variation

    International Nuclear Information System (INIS)

    Kumazawa, R.; Saito, K.; Kasahara, H.; Seki, T.; Mutoh, T.; Shimpo, F.; Nomura, G.; Kato, A.; Okada, H.; Zhao, Y.; Kwak, J.G.; Yoon, J.S.

    2008-01-01

    Ion cyclotron range of frequency (ICRF) heating has been a reliable tool for steady-state plasma heating with high RF power of several tens of megawatts. However, a sudden increase in the reflected RF power during ICRF heating experiments with ELMy H-mode plasmas is an issue which must be solved for future fusion experimental devices or fusion reactors. This paper describes an innovative ICRF heating system using a frequency feedback control to reduce the reflected power in response to the rapid change in the plasma impedance in the ELMy H-mode plasma. A twin stub tuner has been newly invented for this purpose. The feasibility of keeping the reflected RF power fraction at a low level, e.g. 1%, is demonstrated even with a large change in plasma resistance, e.g. 2 ∼ 8Ω. Calculated and experimental results are presented for the conventional double stub tuner impedance matching system equipped with the twin stub tuner.

  10. CATEGORIES AND TOOLS FOR MANAGING THE INTEGRATED PROJECTS AND PROGRAMS OF INNOVATIVE DEVELOPMENT OF GEOTRIONS IN RUSSIA

    Directory of Open Access Journals (Sweden)

    Chudin Anatoly Andreyevich

    2013-05-01

    Full Text Available "An integrated approach to managing the development of the innovative three-component systems, including "population” (social sphere, economy (industrial sphere, and territory (regional sphere, has been developed." These spheres of innovative development have the earth coordinates, are linked non-continuously but inseparably, so they can be analyzed only comprehensively. Following N.D. Matrusov [1] we will call them geotrions. The most important problems in geotrion management are considered in many researches, including [2, 3, 4]. The developed approach serves to overcome many obstacles to the effective development of the innovation process in Russia. The work identifies its basic categories, tools and technologies. The developed approach has revealed the minimum full table of the most significant parameters in the management of the innovation process in the geotrion (parameters of the order and integral parameters of the interaction between the processes, which provided a simple model and the effectiveness of management, through the use of its own power.

  11. Effects of research tool patents on biotechnology innovation in a developing country: A case study of South Korea

    Directory of Open Access Journals (Sweden)

    Ryu Tae-Kyu

    2009-03-01

    Full Text Available Abstract Background Concerns have recently been raised about the negative effects of patents on innovation. In this study, the effects of patents on innovations in the Korean biotech SMEs (small and medium-sized entrepreneurs were examined using survey data and statistical analysis. Results The survey results of this study provided some evidence that restricted access problems have occurred even though their frequency was not high. Statistical analysis revealed that difficulties in accessing patented research tools were not negatively correlated with the level of innovation performance and attitudes toward the patent system. Conclusion On the basis of the results of this investigation in combination with those of previous studies, we concluded that although restricted access problems have occurred, this has not yet deterred innovation in Korea. However, potential problems do exist, and the effects of restricted access should be constantly scrutinized.

  12. Effects of research tool patents on biotechnology innovation in a developing country: a case study of South Korea.

    Science.gov (United States)

    Kang, Kyung-Nam; Ryu, Tae-Kyu; Lee, Yoon-Sik

    2009-03-26

    Concerns have recently been raised about the negative effects of patents on innovation. In this study, the effects of patents on innovations in the Korean biotech SMEs (small and medium-sized entrepreneurs) were examined using survey data and statistical analysis. The survey results of this study provided some evidence that restricted access problems have occurred even though their frequency was not high. Statistical analysis revealed that difficulties in accessing patented research tools were not negatively correlated with the level of innovation performance and attitudes toward the patent system. On the basis of the results of this investigation in combination with those of previous studies, we concluded that although restricted access problems have occurred, this has not yet deterred innovation in Korea. However, potential problems do exist, and the effects of restricted access should be constantly scrutinized.

  13. Materials modelling - a possible design tool for advanced nuclear applications

    International Nuclear Information System (INIS)

    Hoffelner, W.; Samaras, M.; Bako, B.; Iglesias, R.

    2008-01-01

    The design of components for power plants is usually based on codes, standards and design rules or code cases. However, it is very difficult to get the necessary experimental data to prove these lifetime assessment procedures for long-term applications in environments where complex damage interactions (temperature, stress, environment, irradiation) can occur. The rules used are often very simple and do not have a basis which take physical damage into consideration. The linear life fraction rule for creep and fatigue interaction can be taken as a prominent example. Materials modelling based on a multi-scale approach in principle provides a tool to convert microstructural findings into mechanical response and therefore has the capability of providing a set of tools for the improvement of design life assessments. The strength of current multi-scale modelling efforts is the insight they offer as regards experimental phenomena. To obtain an understanding of these phenomena it is import to focus on issues which are important at the various time and length scales of the modelling code. In this presentation the multi-scale path will be demonstrated with a few recent examples which focus on VHTR applications. (authors)

  14. Competency Assessment Tool (CAT). The Evaluation of an Innovative Competency-Based Assessment Experience in Higher Education

    Science.gov (United States)

    Ion, Georgeta; Cano, Elena; Cabrera, Nati

    2016-01-01

    This article examines an innovation in teaching-learning and assessment processes through the use of a platform called the Competency Assessment Tool (CAT). It allows for the tracking of student blogs with the objective of improving self-reflective processes and providing feedback. The experiment was carried out in six universities in Catalonia,…

  15. Play it forward : A Game-based tool for Sustainable Product and Business Model Innovation in the Fuzzy Front End

    NARCIS (Netherlands)

    Dewulf, K.R.

    2010-01-01

    Dealing with sustainability in the fuzzy front end of innovation is complex and often hard. There are a number of tools available to guide designers, engineers and managers in the design process after the specifications of the product or service are already set, but methods supporting goal finding

  16. Requirements for advanced decision support tools in future distribution network planning

    NARCIS (Netherlands)

    Grond, M.O.W.; Morren, J.; Slootweg, J.G.

    2013-01-01

    This paper describes the need and requirements for advanced decision support tools in future network planning from a distribution network operator perspective. The existing tools will no longer be satisfactory for future application due to present developments in the electricity sector that increase

  17. Advanced REACH Tool : Development and application of the substance emission potential modifying factor

    NARCIS (Netherlands)

    Tongeren, M. van; Fransman, W.; Spankie, S.; Tischer, M.; Brouwer, D.; Schinkel, J.; Cherrie, J.W.; Tielemans, E.

    2011-01-01

    The Advanced REACH Tool (ART) is an exposure assessment tool that combines mechanistically modelled inhalation exposure estimates with available exposure data using a Bayesian approach. The mechanistic model is based on nine independent principal modifying factors (MF). One of these MF is the

  18. Advanced ion trap structures with integrated tools for qubit manipulation

    Science.gov (United States)

    Sterk, J. D.; Benito, F.; Clark, C. R.; Haltli, R.; Highstrete, C.; Nordquist, C. D.; Scott, S.; Stevens, J. E.; Tabakov, B. P.; Tigges, C. P.; Moehring, D. L.; Stick, D.; Blain, M. G.

    2012-06-01

    We survey the ion trap fabrication technologies available at Sandia National Laboratories. These include four metal layers, precision backside etching, and low profile wirebonds. We demonstrate loading of ions in a variety of ion traps that utilize these technologies. Additionally, we present progress towards integration of on-board filtering with trench capacitors, photon collection via an optical cavity, and integrated microwave electrodes for localized hyperfine qubit control and magnetic field gradient quantum gates. [4pt] This work was supported by Sandia's Laboratory Directed Research and Development (LDRD) Program and the Intelligence Advanced Research Projects Activity (IARPA). Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the US Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

  19. Water quality management of aquifer recharge using advanced tools.

    Science.gov (United States)

    Lazarova, Valentina; Emsellem, Yves; Paille, Julie; Glucina, Karl; Gislette, Philippe

    2011-01-01

    Managed aquifer recharge (MAR) with recycled water or other alternative resources is one of the most rapidly growing techniques that is viewed as a necessity in water-short areas. In order to better control health and environmental effects of MAR, this paper presents two case studies demonstrating how to improve water quality, enable reliable tracing of injected water and better control and manage MAR operation in the case of indirect and direct aquifer recharge. Two water quality management strategies are illustrated on two full-scale case studies, including the results of the combination of non conventional and advanced technologies for water quality improvement, comprehensive sampling and monitoring programs including emerging pollutants, tracer studies using boron isotopes and integrative aquifer 3D GIS hydraulic and hydrodispersive modelling.

  20. Allogeneic mesenchymal precursor cells (MPCs): an innovative approach to treating advanced heart failure.

    Science.gov (United States)

    Westerdahl, Daniel E; Chang, David H; Hamilton, Michele A; Nakamura, Mamoo; Henry, Timothy D

    2016-09-01

    Over 37 million people worldwide are living with Heart Failure (HF). Advancements in medical therapy have improved mortality primarily by slowing the progression of left ventricular dysfunction and debilitating symptoms. Ultimately, heart transplantation, durable mechanical circulatory support (MCS), or palliative care are the only options for patients with end-stage HF. Regenerative therapies offer an innovative approach, focused on reversing myocardial dysfunction and restoring healthy myocardial tissue. Initial clinical trials using autologous (self-donated) bone marrow mononuclear cells (BMMCs) demonstrated excellent safety, but only modest efficacy. Challenges with autologous stem cells include reduced quality and efficacy with increased patient age. The use of allogeneic mesenchymal precursor cells (MPCs) offers an "off the shelf" therapy, with consistent potency and less variability than autologous cells. Preclinical and initial clinical trials with allogeneic MPCs have been encouraging, providing the support for a large ongoing Phase III trial-DREAM-HF. We provide a comprehensive review of preclinical and clinical data supporting MPCs as a therapeutic option for HF patients. The current data suggest allogeneic MPCs are a promising therapy for HF patients. The results of DREAM-HF will determine whether allogeneic MPCs can decrease major adverse clinical events (MACE) in advanced HF patients.

  1. Advancing innovations in social/personality psychology and health: opportunities and challenges.

    Science.gov (United States)

    Rothman, Alexander J; Klein, William M P; Cameron, Linda D

    2013-05-01

    Social, personality, and health psychologists have a long tradition of active and productive collaborations that have advanced the development of intervention strategies that promote health and well-being and the specification of the theoretical principles that underlie those strategies. This special issue is designed to continue this tradition of collaboration and to highlight areas of research and investigative strategies that offer opportunities for innovation. This concluding paper examines how investigators construe the interface between theory and practice and, with that lens, considers several themes that have emerged across the papers that comprise this special issue. As evidenced by the papers in this special issue, investigators are well-positioned to leverage advances in understanding of human health and well-being. However, to capitalize on this opportunity, investigators need to commit to cultivating a culture of scientific activity that prioritizes the engagement of theory and practice-the pursuit of both understanding and use. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  2. Advanced Recyclable Media System reg-sign. Innovative technology summary report

    International Nuclear Information System (INIS)

    1998-12-01

    The objective of the Large-Scale Demonstration Project (LSDP) is to select and demonstrate potentially beneficial technologies at the Argonne National Laboratory East's (ANL) Chicago Pile-5 (CP-5) Research Reactor. The purpose of the LSDP is to demonstrate that using innovative and improved deactivation and decommissioning (D and D) technologies from various sources can result in significant benefits, such as decreased cost and increased health and safety, as compared with baseline D and D technologies. This report describes a demonstration of the Advanced Recyclable Media System reg-sign technology which was employed by Surface Technology Systems, Inc. to remove coatings from a concrete floor. This demonstration is part of the CP-5 LSDP sponsored by the US Department of Energy (DOE) Office of Science and Technology Deactivation and Decommissioning Focus Area (DDFA). The Advanced Recyclable Media System reg-sign (ARMS) technology is an open blast technology which uses a soft recyclable media. The patented ARMS Engineered Blast Media consists of a fiber-reinforced polymer matrix which can be manufactured in various grades of abrasiveness. The fiber media can be remade and/or reused up to 20 times and can clean almost any surface (e.g., metal, wood, concrete, lead) and geometry including corners and the inside of air ducts

  3. Penile prosthesis implant: scientific advances and technological innovations over the last four decades.

    Science.gov (United States)

    Chung, Eric

    2017-02-01

    Despite introduction of oral phosphodiesterase type 5 inhibitors and intracavernosal vasoactive agents, penile prosthesis implant remains a relevant and desired option with sales of penile prostheses continue to stay high, as many men became refractory to medical therapy and/or seeking a more effective and permanent therapy. There are two types of penile prosthesis implants: inflatable and non-inflatable types, and the inflatable penile implants can be subdivided into single-, two- and three-piece devices. Non-inflatable penile prosthesis (non-IPP) may be referred to as semi-rigid rod or malleable prosthesis. IPP is considered a superior option to malleable prosthesis as it produces penile rigidity and flaccidity that closely replicates a normal penile erectile function. Since the introduction of IPP by Scott in 1973, surgical landscape for penile prosthesis implantation has changed dramatically. Advances in prosthesis design, device technologies and surgical techniques have made penile prosthesis implant a more natural, durable and reliable device. The following article reviews the scientific advances and technological innovation in modern penile prosthesis implants over the last four decades.

  4. tkLayout: a design tool for innovative silicon tracking detectors

    Science.gov (United States)

    Bianchi, G.

    2014-03-01

    A new CMS tracker is scheduled to become operational for the LHC Phase 2 upgrade in the early 2020's. tkLayout is a software package developed to create 3d models for the design of the CMS tracker and to evaluate its fundamental performance figures. The new tracker will have to cope with much higher luminosity conditions, resulting in increased track density, harsher radiation exposure and, especially, much higher data acquisition bandwidth, such that equipping the tracker with triggering capabilities is envisaged. The design of an innovative detector involves deciding on an architecture offering the best trade-off among many figures of merit, such as tracking resolution, power dissipation, bandwidth, cost and so on. Quantitatively evaluating these figures of merit as early as possible in the design phase is of capital importance and it is best done with the aid of software models. tkLayout is a flexible modeling tool: new performance estimates and support for different detector geometries can be quickly added, thanks to its modular structure. Besides, the software executes very quickly (about two minutes), so that many possible architectural variations can be rapidly modeled and compared, to help in the choice of a viable detector layout and then to optimize it. A tracker geometry is generated from simple configuration files, defining the module types, layout and materials. Support structures are automatically added and services routed to provide a realistic tracker description. The tracker geometries thus generated can be exported to the standard CMS simulation framework (CMSSW) for full Monte Carlo studies. tkLayout has proven essential in giving guidance to CMS in studying different detector layouts and exploring the feasibility of innovative solutions for tracking detectors, in terms of design, performance and projected costs. This tool has been one of the keys to making important design decisions for over five years now and has also enabled project engineers

  5. Advanced Epi Tools for Gallium Nitride Light Emitting Diode Devices

    Energy Technology Data Exchange (ETDEWEB)

    Patibandla, Nag; Agrawal, Vivek

    2012-12-01

    Over the course of this program, Applied Materials, Inc., with generous support from the United States Department of Energy, developed a world-class three chamber III-Nitride epi cluster tool for low-cost, high volume GaN growth for the solid state lighting industry. One of the major achievements of the program was to design, build, and demonstrate the world’s largest wafer capacity HVPE chamber suitable for repeatable high volume III-Nitride template and device manufacturing. Applied Materials’ experience in developing deposition chambers for the silicon chip industry over many decades resulted in many orders of magnitude reductions in the price of transistors. That experience and understanding was used in developing this GaN epi deposition tool. The multi-chamber approach, which continues to be unique in the ability of the each chamber to deposit a section of the full device structure, unlike other cluster tools, allows for extreme flexibility in the manufacturing process. This robust architecture is suitable for not just the LED industry, but GaN power devices as well, both horizontal and vertical designs. The new HVPE technology developed allows GaN to be grown at a rate unheard of with MOCVD, up to 20x the typical MOCVD rates of 3{micro}m per hour, with bulk crystal quality better than the highest-quality commercial GaN films grown by MOCVD at a much cheaper overall cost. This is a unique development as the HVPE process has been known for decades, but never successfully commercially developed for high volume manufacturing. This research shows the potential of the first commercial-grade HVPE chamber, an elusive goal for III-V researchers and those wanting to capitalize on the promise of HVPE. Additionally, in the course of this program, Applied Materials built two MOCVD chambers, in addition to the HVPE chamber, and a robot that moves wafers between them. The MOCVD chambers demonstrated industry-leading wavelength yield for GaN based LED wafers and industry

  6. Analysis of Sequence Diagram Layout in Advanced UML Modelling Tools

    Directory of Open Access Journals (Sweden)

    Ņikiforova Oksana

    2016-05-01

    Full Text Available System modelling using Unified Modelling Language (UML is the task that should be solved for software development. The more complex software becomes the higher requirements are stated to demonstrate the system to be developed, especially in its dynamic aspect, which in UML is offered by a sequence diagram. To solve this task, the main attention is devoted to the graphical presentation of the system, where diagram layout plays the central role in information perception. The UML sequence diagram due to its specific structure is selected for a deeper analysis on the elements’ layout. The authors research represents the abilities of modern UML modelling tools to offer automatic layout of the UML sequence diagram and analyse them according to criteria required for the diagram perception.

  7. AN ADVANCED TOOL FOR APPLIED INTEGRATED SAFETY MANAGEMENT

    Energy Technology Data Exchange (ETDEWEB)

    Potts, T. Todd; Hylko, James M.; Douglas, Terence A.

    2003-02-27

    WESKEM, LLC's Environmental, Safety and Health (ES&H) Department had previously assessed that a lack of consistency, poor communication and using antiquated communication tools could result in varying operating practices, as well as a failure to capture and disseminate appropriate Integrated Safety Management (ISM) information. To address these issues, the ES&H Department established an Activity Hazard Review (AHR)/Activity Hazard Analysis (AHA) process for systematically identifying, assessing, and controlling hazards associated with project work activities during work planning and execution. Depending on the scope of a project, information from field walkdowns and table-top meetings are collected on an AHR form. The AHA then documents the potential failure and consequence scenarios for a particular hazard. Also, the AHA recommends whether the type of mitigation appears appropriate or whether additional controls should be implemented. Since the application is web based, the information is captured into a single system and organized according to the >200 work activities already recorded in the database. Using the streamlined AHA method improved cycle time from over four hours to an average of one hour, allowing more time to analyze unique hazards and develop appropriate controls. Also, the enhanced configuration control created a readily available AHA library to research and utilize along with standardizing hazard analysis and control selection across four separate work sites located in Kentucky and Tennessee. The AHR/AHA system provides an applied example of how the ISM concept evolved into a standardized field-deployed tool yielding considerable efficiency gains in project planning and resource utilization. Employee safety is preserved through detailed planning that now requires only a portion of the time previously necessary. The available resources can then be applied to implementing appropriate engineering, administrative and personal protective equipment

  8. The virtual supermarket: an innovative research tool to study consumer food purchasing behaviour.

    Science.gov (United States)

    Waterlander, Wilma E; Scarpa, Michael; Lentz, Daisy; Steenhuis, Ingrid H M

    2011-07-25

    Economic interventions in the food environment are expected to effectively promote healthier food choices. However, before introducing them on a large scale, it is important to gain insight into the effectiveness of economic interventions and peoples' genuine reactions to price changes. Nonetheless, because of complex implementation issues, studies on price interventions are virtually non-existent. This is especially true for experiments undertaken in a retail setting. We have developed a research tool to study the effects of retail price interventions in a virtual-reality setting: the Virtual Supermarket. This paper aims to inform researchers about the features and utilization of this new software application. The Virtual Supermarket is a Dutch-developed three-dimensional software application in which study participants can shop in a manner comparable to a real supermarket. The tool can be used to study several food pricing and labelling strategies. The application base can be used to build future extensions and could be translated into, for example, an English-language version. The Virtual Supermarket contains a front-end which is seen by the participants, and a back-end that enables researchers to easily manipulate research conditions. The application keeps track of time spent shopping, number of products purchased, shopping budget, total expenditures and answers on configurable questionnaires. All data is digitally stored and automatically sent to a web server. A pilot study among Dutch consumers (n = 66) revealed that the application accurately collected and stored all data. Results from participant feedback revealed that 83% of the respondents considered the Virtual Supermarket easy to understand and 79% found that their virtual grocery purchases resembled their regular groceries. The Virtual Supermarket is an innovative research tool with a great potential to assist in gaining insight into food purchasing behaviour. The application can be obtained via an URL

  9. The virtual supermarket: An innovative research tool to study consumer food purchasing behaviour

    Directory of Open Access Journals (Sweden)

    Steenhuis Ingrid HM

    2011-07-01

    Full Text Available Abstract Background Economic interventions in the food environment are expected to effectively promote healthier food choices. However, before introducing them on a large scale, it is important to gain insight into the effectiveness of economic interventions and peoples' genuine reactions to price changes. Nonetheless, because of complex implementation issues, studies on price interventions are virtually non-existent. This is especially true for experiments undertaken in a retail setting. We have developed a research tool to study the effects of retail price interventions in a virtual-reality setting: the Virtual Supermarket. This paper aims to inform researchers about the features and utilization of this new software application. Results The Virtual Supermarket is a Dutch-developed three-dimensional software application in which study participants can shop in a manner comparable to a real supermarket. The tool can be used to study several food pricing and labelling strategies. The application base can be used to build future extensions and could be translated into, for example, an English-language version. The Virtual Supermarket contains a front-end which is seen by the participants, and a back-end that enables researchers to easily manipulate research conditions. The application keeps track of time spent shopping, number of products purchased, shopping budget, total expenditures and answers on configurable questionnaires. All data is digitally stored and automatically sent to a web server. A pilot study among Dutch consumers (n = 66 revealed that the application accurately collected and stored all data. Results from participant feedback revealed that 83% of the respondents considered the Virtual Supermarket easy to understand and 79% found that their virtual grocery purchases resembled their regular groceries. Conclusions The Virtual Supermarket is an innovative research tool with a great potential to assist in gaining insight into food

  10. The virtual supermarket: An innovative research tool to study consumer food purchasing behaviour

    Science.gov (United States)

    2011-01-01

    Background Economic interventions in the food environment are expected to effectively promote healthier food choices. However, before introducing them on a large scale, it is important to gain insight into the effectiveness of economic interventions and peoples' genuine reactions to price changes. Nonetheless, because of complex implementation issues, studies on price interventions are virtually non-existent. This is especially true for experiments undertaken in a retail setting. We have developed a research tool to study the effects of retail price interventions in a virtual-reality setting: the Virtual Supermarket. This paper aims to inform researchers about the features and utilization of this new software application. Results The Virtual Supermarket is a Dutch-developed three-dimensional software application in which study participants can shop in a manner comparable to a real supermarket. The tool can be used to study several food pricing and labelling strategies. The application base can be used to build future extensions and could be translated into, for example, an English-language version. The Virtual Supermarket contains a front-end which is seen by the participants, and a back-end that enables researchers to easily manipulate research conditions. The application keeps track of time spent shopping, number of products purchased, shopping budget, total expenditures and answers on configurable questionnaires. All data is digitally stored and automatically sent to a web server. A pilot study among Dutch consumers (n = 66) revealed that the application accurately collected and stored all data. Results from participant feedback revealed that 83% of the respondents considered the Virtual Supermarket easy to understand and 79% found that their virtual grocery purchases resembled their regular groceries. Conclusions The Virtual Supermarket is an innovative research tool with a great potential to assist in gaining insight into food purchasing behaviour. The

  11. Vγ9Vδ2 T cells as a promising innovative tool for immunotherapy of hematologic malignancies

    Directory of Open Access Journals (Sweden)

    Serena Meraviglia

    2011-12-01

    Full Text Available The potent anti-tumor activities of γδ T cells, their ability to produce pro-inflammatory cytokines, and their strong cytolytic activity have prompted the development of protocols in which γδ agonists or ex vivo-expanded γδ cells are administered to tumor patients. γδ T cells can be selectively activated by either synthetic phosphoantigens or by drugs that enhance their accumulation into stressed cells as aminobisphosphonates, thus offering new avenues for the development of γδ T cell-based immunotherapies. The recent development of small drugs selectively activating Vγ9Vδ2 T lymphocytes, which upregulate the endogenous phosphoantigens, has enabled the investigators to design the experimental approaches of cancer immunotherapies; several ongoing phase I and II clinical trials are focused on the role of the direct bioactivity of drugs and of adoptive cell therapies involving phosphoantigen- or aminobisphosphonate-activated Vγ9Vδ2 T lymphocytes in humans. In this review, we focus on the recent advances in the activation/expansion of γδ T cells in vitro and in vivo that may represent a promising target for the design of novel and highly innovative immunotherapy in patients with hematologic malignancies.

  12. Grand Challenges of Advanced Computing for Energy Innovation Report from the Workshop Held July 31-August 2, 2012

    Energy Technology Data Exchange (ETDEWEB)

    Larzelere, Alex R.; Ashby, Steven F.; Christensen, Dana C.; Crawford, Dona L.; Khaleel, Mohammad A.; John, Grosh; Stults, B. Ray; Lee, Steven L.; Hammond, Steven W.; Grover, Benjamin T.; Neely, Rob; Dudney, Lee Ann; Goldstein, Noah C.; Wells, Jack; Peltz, Jim

    2013-03-06

    On July 31-August 2 of 2012, the U.S. Department of Energy (DOE) held a workshop entitled Grand Challenges of Advanced Computing for Energy Innovation. This workshop built on three earlier workshops that clearly identified the potential for the Department and its national laboratories to enable energy innovation. The specific goal of the workshop was to identify the key challenges that the nation must overcome to apply the full benefit of taxpayer-funded advanced computing technologies to U.S. energy innovation in the ways that the country produces, moves, stores, and uses energy. Perhaps more importantly, the workshop also developed a set of recommendations to help the Department overcome those challenges. These recommendations provide an action plan for what the Department can do in the coming years to improve the nation’s energy future.

  13. Target Costing as a Strategic Tool to Commercialize the Product and Service Innovation

    DEFF Research Database (Denmark)

    Jiang, Liping; Hansen, Carsten Ørts

    What is the issue? Innovation is an important key to success in today's competitive marketplace. Firms therefore have strived hard to innovate and stay ahead. However, they have to face the brutal fact that firms often fail to obtain the commercial success of innovation. Why is it important......? With keen international competition and accelerating pace of technology change, the ability to introduce innovations into the market and capture the profits generated by an innovation is of strategic importance. It can put a firm at a competitive advantage and build a firm’s sustainable financial benefits....... What can be done? The implementation of target costing will increase the odds of commercial success of an innovation. It aims at fulfilling the economic potential of an innovation by focusing on the market and customers during the design and price setting stages. This price will, on one hand, impose...

  14. Findings: Sector-Leading and Innovative Practice in Advancing Equality and Diversity. Report to HEFCE by the Equality Challenge Unit

    Science.gov (United States)

    Higher Education Funding Council for England, 2017

    2017-01-01

    Following our "Call for evidence of sector-leading and innovative practice in advancing equality and diversity" (HEFCE Circular letter 16/2016), HEFCE commissioned the Equality Challenge Unit (ECU) to report back on the range of equality and diversity practice undertaken across the higher education sector. Of 120 submissions received,…

  15. How innovative ICT tools can enhance understanding of interactions between societal, hydrological and environmental changes

    Science.gov (United States)

    Foglia, L.; Borsi, I.; Cannata, M.; De Filippis, G.; Criollo, R.; Mehl, S.; Rossetto, R.

    2017-12-01

    The interaction of environmental, physical, and socioeconomic processes alter and are altered by water and by how human can affect water use. For example, a warming climate increases the chance of warm temperatures and lack of precipitation, and when combined with growing population requires understanding of impact on water resources and on all the processes related to the water budget including evapotranspiration. On this foundation, humans add engineered and social systems to control, manage, utilize, and alter our water environment for a variety of uses and through a variety of organizational and individual decisions. Some engineered systems have mixed consequences, for example groundwater helped sustain agriculture during drought periods, but then groundwater levels critically decrease with no chances to recover in some parts of the world. Innovative ICT tools have been demonstrated as a helpful tool for enhancing human understanding of the effect that societal, economical, and policy-based decisions have on the water resources and on the environment in general. Here we apply the new FREEWAT platform to demonstrate the importance of developing ad-hoc database and hydrological models to simulate different scenarios using a participatory approach. Stakeholders have been involved in data collection, database design and model development during the entire project period and discussion between researcher and stakeholders have been fostered during Focus Groups and workshops organized in many countries in Europe and beyond (including case studies in Ukraine and Africa). FREEWAT is an open source and public domain GIS integrated modelling environment for simulation of water quantity and quality in surface water and groundwater with an integrated water management and planning module. FREEWAT aims at promoting water resource management by simplifying the application of the Water Framework Directive and related Directives. Fourteen case studies have been considered and

  16. Action Observation and Motor Imagery: Innovative Cognitive Tools in the Rehabilitation of Parkinson’s Disease

    Directory of Open Access Journals (Sweden)

    Giovanni Abbruzzese

    2015-01-01

    Full Text Available Parkinson’s disease (PD is characterized by a progressive impairment of motor skills with deterioration of autonomy in daily living activities. Physiotherapy is regarded as an adjuvant to pharmacological and neurosurgical treatment and may provide small and short-lasting clinical benefits in PD patients. However, the development of innovative rehabilitation approaches with greater long-term efficacy is a major unmet need. Motor imagery (MI and action observation (AO have been recently proposed as a promising rehabilitation tool. MI is the ability to imagine a movement without actual performance (or muscle activation. The same cortical-subcortical network active during motor execution is engaged in MI. The physiological basis of AO is represented by the activation of the “mirror neuron system.” Both MI and AO are involved in motor learning and can induce improvements of motor performance, possibly mediated by the development of plastic changes in the motor cortex. The review of available evidences indicated that MI ability and AO feasibility are substantially preserved in PD subjects. A few preliminary studies suggested the possibility of using MI and AO as parts of rehabilitation protocols for PD patients.

  17. Innovative data tools: a suite for managing peer outreach to key affected populations in Viet Nam.

    Science.gov (United States)

    Nga, Nguyen Thien; Jacka, David; Van Hai, Nguyen; Trinh, Nguyen Kieu; Boisen, Neil; Neukom, Josselyn

    2012-07-01

    The paper tools used to monitor outreach work in all major cities in Viet Nam had substantial writing requirements for each contact with difficulty maintaining confidentiality. This paper describes the development of a Unique Identifier Code (UIC), a field data collection notebook (databook) and a computer data entry system in Viet Nam. The databook can document 40 individual clients and has space for commodity distribution, group contacts and needles/syringe collection for each month. Field implementation trials of the UIC and databook have been undertaken by more than 160 peer outreach workers to document their work with people who inject drugs (PWID) and sex workers (SW). Following an expanded trial in Hai Phong province, there have been requests for national circulation of the databook to be used by peer educators documenting outreach to PWID, SW and men who have sex with men. The standardized UIC and databook, in a variety of locally adapted formats, have now been introduced in more than 40 of the 63 provinces in Viet Nam. This development in Viet Nam is, to our knowledge, the first example of the combination of a confidential UIC and an innovative, simple pocket-sized paper instrument with associated customized data-entry software for documenting outreach.

  18. tkLayout: a Design Tool for Innovative Silicon Tracking Detectors

    CERN Document Server

    Bianchi, Giovanni

    2014-01-01

    A new CMS tracker is scheduled to become operational for the LHC Phase 2 upgrade in the early 2020's. tkLayout is a software package developed to create 3d models for the design of the CMS tracker and to evaluate its fundamental performance figures. The new tracker will have to cope with much higher luminosity conditions, resulting in increased track density, harsher radiation exposure and, especially, much higher data acquisition bandwidth, such that equipping the tracker with triggering capabilities is envisaged. The design of an innovative detector involves deciding on an architecture offering the best trade-off among many figures of merit, such as tracking resolution, power dissipation, bandwidth, cost and so on. Quantitatively evaluating these figures of merit as early as possible in the design phase is of capital importance and it is best done with the aid of software models. tkLayout is a flexible modeling tool: new performance estimates and support for different detector geometries can be quickly ad...

  19. Powerful tools for genetic modification: Advances in gene editing.

    Science.gov (United States)

    Roesch, Erica A; Drumm, Mitchell L

    2017-11-01

    Recent discoveries and technical advances in genetic engineering, methods called gene or genome editing, provide hope for repairing genes that cause diseases like cystic fibrosis (CF) or otherwise altering a gene for therapeutic benefit. There are both hopes and hurdles with these technologies, with new ideas emerging almost daily. Initial studies using intestinal organoid cultures carrying the common, F508del mutation have shown that gene editing by CRISPR/Cas9 can convert cells lacking CFTR function to cells with normal channel function, providing a precedent that this technology can be harnessed for CF. While this is an important precedent, the challenges that remain are not trivial. A logistical issue for this and many other genetic diseases is genetic heterogeneity. Approximately, 2000 mutations associated with CF have been found in CFTR, the gene responsible for CF, and thus a feasible strategy that would encompass all individuals affected by the disease is particularly difficult to envision. However, single strategies that would be applicable to all subjects affected by CF have been conceived and are being investigated. With all of these approaches, efficiency (the proportion of cells edited), accuracy (how often other sites in the genome are affected), and delivery of the gene editing components to the desired cells are perhaps the most significant, impending hurdles. Our understanding of each of these areas is increasing rapidly, and while it is impossible to predict when a successful strategy will reach the clinic, there is every reason to believe it is a question of "when" and not "if." © 2017 Wiley Periodicals, Inc.

  20. Innovations in the Endovascular Management of Critical Limb Ischemia: Retrograde Tibiopedal Access and Advanced Percutaneous Techniques.

    Science.gov (United States)

    Mustapha, Jihad A; Diaz-Sandoval, Larry J; Saab, Fadi

    2017-08-01

    Retrograde tibiopedal access and interventions have contributed to advance of endovascular techniques to treat critical limb ischemia (CLI) patients. This review encompasses the spectrum from advanced diagnostic imaging and technical therapeutic approaches for infrapopliteal occlusions, to a discussion of current standards and future directions. Contemporary studies of infrapopliteal angioplasty show suboptimal short-term and 1-year clinical outcomes. Comparative data is needed to shift the focus from PTA to disruptive treatment modalities that can further improve outcomes. Retrograde pedal access has emerged as an important tool to facilitate successfully percutaneous revascularization and limb salvage in patients with CLI. To efficiently approach the complexity of CLI, new thought processes are needed to change the reigning paradigms. Retrograde tibial-pedal access has shown improvement in the rate of successful revascularizations and is an important tool in the amputation-prevention armamentarium. Additional technologies may further improve success rates. Drug-eluting stents have shown better outcomes than PTA in patients with focal infrapopliteal lesions. Registry data have demonstrated the advantage of several atherectomy devices in the tibial arteries. More recently, bioresorbable vascular scaffolds have been used successfully, and further studies with drug-coated balloons are underway. Interventional operators are now even working in the inframalleolar space to reconstitute the plantar arch. Well-conducted studies are needed to generate high-quality evidence in the field of critical limb ischemia management.

  1. Advancing alternate tools: why science education needs CRP and CRT

    Science.gov (United States)

    Dodo Seriki, Vanessa

    2018-03-01

    Ridgeway and Yerrick's paper, Whose banner are we waving?: exploring STEM partnerships for marginalized urban youth, unearthed the tensions that existed between a local community "expert" and a group of students and their facilitator in an afterschool program. Those of us who work with youth who are traditionally marginalized, understand the importance of teaching in culturally relevant ways, but far too often—as Ridgeway and Yerrick shared—community partners have beliefs, motives, and ideologies that are incompatible to the program's mission and goals. Nevertheless, we often enter partnerships assuming that the other party understands the needs of the students or community; understands how in U.S. society White is normative while all others are deficient; and understands how to engage with students in culturally relevant ways. This forum addresses the underlying assumption, described in the Ridgeway and Yerrick article, that educators—despite their background and experiences—are able to teach in culturally relevant ways. Additionally, I assert based on the finding in the article that just as Ladson-Billings and Tate (Teach Coll Rec 97(1):47-68, 1995) asserted, race in the U.S. society, as a scholarly pursuit, was under theorized. The same is true of science education; race in science education is under theorized and the use of culturally relevant pedagogy and critical race theory as a pedagogical model and analytical tool, respectively, in science education is minimal. The increased use of both would impact our understanding of who does science, and how to broaden participation among people of color.

  2. Teaching Advanced Data Analysis Tools to High School Astronomy Students

    Science.gov (United States)

    Black, David V.; Herring, Julie; Hintz, Eric G.

    2015-01-01

    A major barrier to becoming an astronomer is learning how to analyze astronomical data, such as using photometry to compare the brightness of stars. Most fledgling astronomers learn observation, data reduction, and analysis skills through an upper division college class. If the same skills could be taught in an introductory high school astronomy class, then more students would have an opportunity to do authentic science earlier, with implications for how many choose to become astronomers. Several software tools have been developed that can analyze astronomical data ranging from fairly straightforward (AstroImageJ and DS9) to very complex (IRAF and DAOphot). During the summer of 2014, a study was undertaken at Brigham Young University through a Research Experience for Teachers (RET) program to evaluate the effectiveness and ease-of-use of these four software packages. Standard tasks tested included creating a false-color IR image using WISE data in DS9, Adobe Photoshop, and The Gimp; a multi-aperture analyses of variable stars over time using AstroImageJ; creating Spectral Energy Distributions (SEDs) of stars using photometry at multiple wavelengths in AstroImageJ and DS9; and color-magnitude and hydrogen alpha index diagrams for open star clusters using IRAF and DAOphot. Tutorials were then written and combined with screen captures to teach high school astronomy students at Walden School of Liberal Arts in Provo, UT how to perform these same tasks. They analyzed image data using the four software packages, imported it into Microsoft Excel, and created charts using images from BYU's 36-inch telescope at their West Mountain Observatory. The students' attempts to complete these tasks were observed, mentoring was provided, and the students then reported on their experience through a self-reflection essay and concept test. Results indicate that high school astronomy students can successfully complete professional-level astronomy data analyses when given detailed

  3. Advanced practice physiotherapy in paediatric orthopaedics: innovation and collaboration to improve service delivery.

    Science.gov (United States)

    Ó Mír, M; O'Sullivan, C

    2018-02-01

    One in eight paediatric primary care presentations is for a musculoskeletal (MSK) disorder. These patients are frequently referred to paediatric orthopaedic surgeons; however, up to 50% of referrals are for normal variants. This results in excessive wait-times and impedes access for urgent surgical cases. Adult MSK medicine has successfully utilised advanced practice physiotherapists (APP) managing non-surgical candidates, with documented benefits both to patients and services. There is a gap in the literature with regard to APP in paediatric orthopaedics. In this review, we investigate demands on paediatric orthopaedic services, examine the literature regarding APP in paediatric orthopaedics and explore the value the role has to offer current outpatient services. Paediatric orthopaedic services are under-resourced with concurrent long wait times. Approximately 50% of referrals are for normal variants, which do not require specialist intervention. Poor musculoskeletal examination skills and low diagnostic confidence amongst primary care physicians have been identified as a cause of inappropriate referrals. APP clinics for normal variants have reported independent management rate and discharge rates of 95% and marked reduction in patient wait times. There is limited evidence to support the APP in paediatric orthopaedics. Further studies are needed investigating diagnostic agreement, patient/stakeholder satisfaction, patient outcomes and economic evaluation. Paediatric orthopaedics is in crisis as to how to effectively manage the overwhelming volume of referrals. Innovative multidisciplinary solutions are required so that the onus is not solely on physicians to provide all services. The APP in paediatric orthopaedics may be part of the solution.

  4. Assimilation Patterns in the Use of Advanced Manufacturing Technologies in SMEs: Exploring their Effects on Product Innovation Performance

    Directory of Open Access Journals (Sweden)

    Sylvestre Uwizeyemungu

    2015-10-01

    Full Text Available Manufacturing small and medium-sized enterprises (SMEs are more and more adopting advanced manufacturing technologies (AMT aimed at fostering product innovation process, improving product quality, streamlining the production process, and gaining productivity. In this study, we analyze the relationship between AMT proficiency levels in manufacturing SMEs and product innovation performance. Using data from 616 manufacturing SMEs, and considering a wide range of various AMT (20 different types of AMT grouped into 5 categories, we derived three AMT assimilation patterns through a cluster analysis procedure combining hierarchical and non-hierarchical clustering algorithms. The analysis of the relationship between AMT assimilation patterns and product innovation performance shows a rather unexpected picture: in spite of the existence of clearly distinct patterns of AMT assimilation, we find no significant relationship between any pattern and product innovation performance. Instead, we find the organizational and environmental context of SMEs to be more determinant for product innovation performance than any of the AMT assimilation patterns. From a practical point of view, this study indicates that manufacturing SMEs managers interested in fostering their innovation capabilities through AMT assimilation need to be aware of the contingency effects of their organizational size, age, and sector of activity.

  5. 3D printing technology as innovative tool for math and geometry teaching applications

    Science.gov (United States)

    Huleihil, M.

    2017-01-01

    The industrial revolution and automation of production processes have changed the face of the world. Three dimensional (3D) printing has the potential to revolutionize manufacturing and further change methods of production toward allowing in increasing number of people to produce products at home. According to a recent OECD (see Backer [1]) publication, “…tapping into the next industrial revolution requires actions on many levels and in many different areas. In particular, unlocking the potential of emerging and enabling technologies requires policy development along a number of fronts, from commercialization to regulation and the supply of skills through education.” In this paper we discuss the role of schools and their responsibility to act as quickly as possible to design a plan of action that will prepare the future citizens to deal with this new reality. This requires planning of action in different directions and on different planes, such as labs, teachers, and curricula. 3D printing requires higher levels of thinking, innovation and creativity. It has the power to develop human imagination and give students the opportunity to visualize numbers, two- dimensional shapes, and three-dimensional objects. The combination of thinking, design, and production has immense power to increase motivation and satisfaction, with a highly probable increase in a student’s math and geometry achievements. The CAD system includes a measure tool which enables and alternative way for calculating properties of the objects under consideration and allows development of reflection and critical thinking. The research method was based on comparison between a reference group and a test group; it was found that intervention significantly improved the reflection abilities of 6th grade students in mathematics.

  6. An innovative multivariate tool for fuel consumption and costs estimation of agricultural operations

    Directory of Open Access Journals (Sweden)

    Mirko Guerrieri

    2016-12-01

    Full Text Available The estimation of operating costs of agricultural and forestry machineries is a key factor in both planning agricultural policies and farm management. Few works have tried to estimate operating costs and the produced models are normally based on deterministic approaches. Conversely, in the statistical model randomness is present and variable states are not described by unique values, but rather by probability distributions. In this study, for the first time, a multivariate statistical model based on Partial Least Squares (PLS was adopted to predict the fuel consumption and costs of six agricultural operations such as: ploughing, harrowing, fertilization, sowing, weed control and shredding. The prediction was conducted on two steps: first of all few initial selected parameters (time per surface-area unit, maximum engine power, purchase price of the tractor and purchase price of the operating machinery were used to estimate the fuel consumption; then the predicted fuel consumption together with the initial parameters were used to estimate the operational costs. Since the obtained models were based on an input dataset very heterogeneous, these resulted to be extremely efficient and so generalizable and robust. In details the results show prediction values in the test with r always ≥ 0.91. Thus, the approach may results extremely useful for both farmers (in terms of economic advantages and at institutional level (representing an innovative and efficient tool for planning future Rural Development Programmes and the Common Agricultural Policy. In light of these advantages the proposed approach may as well be implemented on a web platform and made available to all the stakeholders.

  7. Evaluation of the professional process portfolio: an innovative tool to help develop and demonstrate leadership competency.

    Science.gov (United States)

    Hastings, Elisabeth S; Chacko, Mariam R; Acosta, Amy B; Hergenroeder, Albert C; Wiemann, Constance M

    2015-02-01

    The professional process portfolio (PPP) was adopted by the Maternal Child and Health Bureau (MCHB) as an 'innovation' in best practice for all Leadership in Education and Adolescent Health (LEAH) Training Programs; however it had not been formally evaluated. Thus the objective was to evaluate the utility of the PPP for graduates of the LEAH training program in terms of (1) how alumni have used, adapted, and applied it since completing fellowship, (2) what fellows learned or gained through completing it, and (3) how it can be improved for continued use in training programs. Graduates from six disciplines were asked via telephone or email to participate in a survey regarding their experience with the PPP. Descriptive statistics were generated for demographic characteristics and closed-choice questions. Responses to open-ended questions were analyzed by a team of faculty using framework analysis. Sixty-one graduates completed surveys. The majority (85%) found the PPP useful and utilized it post-graduation for multiple purposes in professional development: interviewing, training, and referencing previous work. Graduates recommended that the PPP be improved by making it electronic, discipline-specific, and providing earlier and more frequent instruction from faculty on expectations of creating it. Four themes emerged from the qualitative data analysis: accomplishment, experiential learning, skills and accountability, and a best practice of learning. The PPP was an effective personal learning tool for the majority of graduates and enhanced graduates' experiences. We highlight the ways that the PPP may facilitate the development of learning experiences associated with MCH leadership competence.

  8. An innovative multivariate tool for fuel consumption and costs estimation of agricultural operations

    International Nuclear Information System (INIS)

    Guerrieri, M.; Fedrizzi, M.; Antonucci, F.; Pallottino, F.; Sperandio, G.; Pagano, M.; Figorilli, S.; Menesatti, P.; Costa, C.

    2016-01-01

    The estimation of operating costs of agricultural and forestry machineries is a key factor in both planning agricultural policies and farm management. Few works have tried to estimate operating costs and the produced models are normally based on deterministic approaches. Conversely, in the statistical model randomness is present and variable states are not described by unique values, but rather by probability distributions. In this study, for the first time, a multivariate statistical model based on Partial Least Squares (PLS) was adopted to predict the fuel consumption and costs of six agricultural operations such as: ploughing, harrowing, fertilization, sowing, weed control and shredding. The prediction was conducted on two steps: first of all few initial selected parameters (time per surface-area unit, maximum engine power, purchase price of the tractor and purchase price of the operating machinery) were used to estimate the fuel consumption; then the predicted fuel consumption together with the initial parameters were used to estimate the operational costs. Since the obtained models were based on an input dataset very heterogeneous, these resulted to be extremely efficient and so generalizable and robust. In details the results show prediction values in the test with r always ≥ 0.91. Thus, the approach may results extremely useful for both farmers (in terms of economic advantages) and at institutional level (representing an innovative and efficient tool for planning future Rural Development Programmes and the Common Agricultural Policy). In light of these advantages the proposed approach may as well be implemented on a web platform and made available to all the stakeholders.

  9. An innovative multivariate tool for fuel consumption and costs estimation of agricultural operations

    Energy Technology Data Exchange (ETDEWEB)

    Guerrieri, M.; Fedrizzi, M.; Antonucci, F.; Pallottino, F.; Sperandio, G.; Pagano, M.; Figorilli, S.; Menesatti, P.; Costa, C.

    2016-07-01

    The estimation of operating costs of agricultural and forestry machineries is a key factor in both planning agricultural policies and farm management. Few works have tried to estimate operating costs and the produced models are normally based on deterministic approaches. Conversely, in the statistical model randomness is present and variable states are not described by unique values, but rather by probability distributions. In this study, for the first time, a multivariate statistical model based on Partial Least Squares (PLS) was adopted to predict the fuel consumption and costs of six agricultural operations such as: ploughing, harrowing, fertilization, sowing, weed control and shredding. The prediction was conducted on two steps: first of all few initial selected parameters (time per surface-area unit, maximum engine power, purchase price of the tractor and purchase price of the operating machinery) were used to estimate the fuel consumption; then the predicted fuel consumption together with the initial parameters were used to estimate the operational costs. Since the obtained models were based on an input dataset very heterogeneous, these resulted to be extremely efficient and so generalizable and robust. In details the results show prediction values in the test with r always ≥ 0.91. Thus, the approach may results extremely useful for both farmers (in terms of economic advantages) and at institutional level (representing an innovative and efficient tool for planning future Rural Development Programmes and the Common Agricultural Policy). In light of these advantages the proposed approach may as well be implemented on a web platform and made available to all the stakeholders.

  10. Energy, economic, and environmental impacts of advanced industrial process innovations, 1976--1996

    International Nuclear Information System (INIS)

    Quinn, J.E.; Reed, J.E.

    1997-01-01

    The mission of the Office of Industrial Technologies (OIT), within the Office of Energy Efficiency and Renewable Energy, is to develop and deploy advanced energy efficiency, renewable energy, and pollution-prevention technologies, through partnerships with industry, government, and non-governmental organizations. OIT's objectives have evolved and broadened over nearly two decades, continually responding to a changing energy situation and shifting national priorities. Today, the key focus of the OIT programs is the Industries of the Future approach. This strategy of close collaboration with industry catalyzes and facilitates technology development and transfer efforts in seven manufacturing industries that together account for over 80% of the energy used and over 80% of the wastes produced by the manufacturing sector. In this approach senior level industry groups develop a future vision of their industry and a technology roadmap to attain the vision. DOE helps facilitate this process and partners with industry to identify and pursue an advanced technology R and D portfolio. The seven industries are aluminum, chemicals, forest products, glass, metalcasting, petroleum refining, and steel. In managing all its activities, OIT draws upon program support provided primarily by national Laboratories, universities, and private-sector research organizations throughout the country that have the diverse and specialized expertise needed to develop advanced industrial technologies. Approximately 78 industrial technologies developed with Office of Industrial Technology (OIT) support have successfully entered commercial markets. These technologies have saved a cumulative total of almost 900 trillion Btu, representing a new production cost savings of over $1.8 billion. These dollar savings represent the net total value of all energy saved by technologies developed with OIT support minus the net cost to industry of using the technologies (including capital costs, operating and

  11. Aerosol processing: a wind of innovation in the field of advanced heterogeneous catalysts.

    Science.gov (United States)

    Debecker, Damien P; Le Bras, Solène; Boissière, Cédric; Chaumonnot, Alexandra; Sanchez, Clément

    2018-04-16

    Aerosol processing is long known and implemented industrially to obtain various types of divided materials and nanomaterials. The atomisation of a liquid solution or suspension produces a mist of aerosol droplets which can then be transformed via a diversity of processes including spray-drying, spray pyrolysis, flame spray pyrolysis, thermal decomposition, micronisation, gas atomisation, etc. The attractive technical features of these aerosol processes make them highly interesting for the continuous, large scale, and tailored production of heterogeneous catalysts. Indeed, during aerosol processing, each liquid droplet undergoes well-controlled physical and chemical transformations, allowing for example to dry and aggregate pre-existing solid particles or to synthesise new micro- or nanoparticles from mixtures of molecular or colloidal precursors. In the last two decades, more advanced reactive aerosol processes have emerged as innovative means to synthesise tailored-made nanomaterials with tunable surface properties, textures, compositions, etc. In particular, the "aerosol-assisted sol-gel" process (AASG) has demonstrated tremendous potential for the preparation of high-performance heterogeneous catalysts. The method is mainly based on the low-cost, scalable, and environmentally benign sol-gel chemistry process, often coupled with the evaporation-induced self-assembly (EISA) concept. It allows producing micronic or submicronic, inorganic or hybrid organic-inorganic particles bearing tuneable and calibrated porous structures at different scales. In addition, pre-formed nanoparticles can be easily incorporated or formed in a "one-pot" bottom-up approach within the porous inorganic or hybrid spheres produced by such spray drying method. Thus, multifunctional catalysts with tailored catalytic activities can be prepared in a relatively simple way. This account is an overview of aerosol processed heterogeneous catalysts which demonstrated interesting performance in

  12. WE-D-BRD-01: Innovation in Radiation Therapy Delivery: Advanced Digital Linac Features

    Energy Technology Data Exchange (ETDEWEB)

    Xing, L [Stanford University, Stanford, CA (United States); Wong, J [Johns Hopkins University, Baltimore, MD (United States); Li, R [Stanford University, Palo Alto, CA (United States)

    2014-06-15

    Last few years has witnessed significant advances in linac technology and therapeutic dose delivery method. Digital linacs equipped with high dose rate FFF beams have been clinically implemented in a number of hospitals. Gated VMAT is becoming increasingly popular in treating tumors affected by respiratory motion. This session is devoted to update the audience with these technical advances and to present our experience in clinically implementing the new linacs and dose delivery methods. Topics to be covered include, technical features of new generation of linacs from different vendors, dosimetric characteristics and clinical need for FFF-beam based IMRT and VMAT, respiration-gated VMAT, the concept and implementation of station parameter optimized radiation therapy (SPORT), beam level imaging and onboard image guidance tools. Emphasis will be on providing fundamental understanding of the new treatment delivery and image guidance strategies, control systems, and the associated dosimetric characteristics. Commissioning and acceptance experience on these new treatment delivery technologies will be reported. Clinical experience and challenges encountered during the process of implementation of the new treatment techniques and future applications of the systems will also be highlighted. Learning Objectives: Present background knowledge of emerging digital linacs and summarize their key geometric and dosimetric features. SPORT as an emerging radiation therapy modality specifically designed to take advantage of digital linacs. Discuss issues related to the acceptance and commissioning of the digital linacs and FFF beams. Describe clinical utility of the new generation of digital linacs and their future applications.

  13. WE-D-BRD-01: Innovation in Radiation Therapy Delivery: Advanced Digital Linac Features

    International Nuclear Information System (INIS)

    Xing, L; Wong, J; Li, R

    2014-01-01

    Last few years has witnessed significant advances in linac technology and therapeutic dose delivery method. Digital linacs equipped with high dose rate FFF beams have been clinically implemented in a number of hospitals. Gated VMAT is becoming increasingly popular in treating tumors affected by respiratory motion. This session is devoted to update the audience with these technical advances and to present our experience in clinically implementing the new linacs and dose delivery methods. Topics to be covered include, technical features of new generation of linacs from different vendors, dosimetric characteristics and clinical need for FFF-beam based IMRT and VMAT, respiration-gated VMAT, the concept and implementation of station parameter optimized radiation therapy (SPORT), beam level imaging and onboard image guidance tools. Emphasis will be on providing fundamental understanding of the new treatment delivery and image guidance strategies, control systems, and the associated dosimetric characteristics. Commissioning and acceptance experience on these new treatment delivery technologies will be reported. Clinical experience and challenges encountered during the process of implementation of the new treatment techniques and future applications of the systems will also be highlighted. Learning Objectives: Present background knowledge of emerging digital linacs and summarize their key geometric and dosimetric features. SPORT as an emerging radiation therapy modality specifically designed to take advantage of digital linacs. Discuss issues related to the acceptance and commissioning of the digital linacs and FFF beams. Describe clinical utility of the new generation of digital linacs and their future applications

  14. Statistical Monitoring of Innovation Capacities of the Serbian Firms as Decision- Making Tool

    Directory of Open Access Journals (Sweden)

    Marija Mosurović Ružičić

    2016-12-01

    Full Text Available The subject of this paper is to underline the importance of using data obtained via the official statistical reports that is based on Oslo manual methodology manual (Community Innovation Survey for strategic decision making both at the national level as well as at the level of the company. These data enable monitoring and evaluating the innovation capacity of the firms with the aim of improving it. The paper, also, points out the importance of the firm's innovation capacity assessment as an impeller of economic development based on knowledge. By the data obtained by presented methodology, national decision makers can clearly comprehend and improve the direction of innovation policy and its integration into the wider policy framework that encourage economic development based on innovation. At the firm level, the use of data implies development of professional management of the innovative firm that will be able to respond to problem situations of the modern economy through the formulation of appropriate strategies. The paper analyzed data from three statistical periods during which the Oslo manual methodology had been applied in Serbia. Analysis has shown that the data obtained in this way are not sufficiently used by decision-makers an occasion rating innovation capacity of enterprises.

  15. The service blueprint as a tool for designing innovative pharmaceutical services.

    Science.gov (United States)

    Holdford, D A; Kennedy, D T

    1999-01-01

    To describe service blueprints, discuss their need and design, and provide examples of their use in advancing pharmaceutical care. Service blueprints are pictures or maps of service processes that permit the people involved in designing, providing, managing, and using the service to better understand them and deal with them objectively. A service blueprint simultaneously depicts the service process and the roles of consumers, service providers, and supporting services. Service blueprints can be useful in pharmacy because many of the obstacles to pharmaceutical care are a result of insufficient planning by service designers and/or poor communication between those designing services and those implementing them. One consequence of this poor design and communication is that many consumers and third party payers are uninformed about pharmacist roles. Service blueprints can be used by pharmacists to promote the value of pharmaceutical care to consumers and other decision makers. They can also assist in designing better pharmaceutical services. Blueprints are designed by identifying and mapping a process from the consumer's point of view, mapping employee actions and support activities, and adding visible evidence of service at each consumer action step. Key components of service blueprints are consumer actions, "onstage" and "backstage" employee actions, and support processes. Blueprints can help pharmacy managers identify and correct problems with the service process, provide pharmacy employees an opportunity to offer feedback in the planning stages of services, and demonstrate the value of pharmaceutical services to consumers. Service blueprints can be a valuable tool for designing, implementing, and evaluating pharmacy services.

  16. Second NASA Technical Interchange Meeting (TIM): Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box (TTB)

    Science.gov (United States)

    ONeil, D. A.; Mankins, J. C.; Christensen, C. B.; Gresham, E. C.

    2005-01-01

    The Advanced Technology Lifecycle Analysis System (ATLAS), a spreadsheet analysis tool suite, applies parametric equations for sizing and lifecycle cost estimation. Performance, operation, and programmatic data used by the equations come from a Technology Tool Box (TTB) database. In this second TTB Technical Interchange Meeting (TIM), technologists, system model developers, and architecture analysts discussed methods for modeling technology decisions in spreadsheet models, identified specific technology parameters, and defined detailed development requirements. This Conference Publication captures the consensus of the discussions and provides narrative explanations of the tool suite, the database, and applications of ATLAS within NASA s changing environment.

  17. Advanced Design Tools for the Lifetime of Power Electronics – Study Case on Motor Drive Application

    DEFF Research Database (Denmark)

    Ma, Ke; Vernica, Ionut; Blaabjerg, Frede

    2016-01-01

    assessment of reliability performance for the power electronics is a crucial and emerging need, because it is the essential information for the reliability improvements, and thus reduction of the cost-of-energy. Unfortunately, there is still lack of suitable tools for the reliability assessment in power...... electronics. In this paper, an advanced design tool structure, which can acquire various reliability metrics of the power electronics, is proposed. The proposed design tool is based on the failure mechanisms in the critical components of the power electronics, and the mission profiles in the converter...

  18. Knowledge management as a strategic tool to foster innovativeness in SMEs

    NARCIS (Netherlands)

    Zhou, H.; Uhlaner, L.M.

    2009-01-01

    This study examines the relationship between knowledge management (KM) (in terms of external acquisition and internal sharing) and innovation behavior. The concept of absorptive capacity and assumptions from the dynamic capabilities view underlie the proposed framework and hypotheses. The framework

  19. Knowledge Management as a Strategic Tool to Foster Innovativeness of SMEs

    NARCIS (Netherlands)

    H. Zhou (Haibo); L.M. Uhlaner (Lorraine)

    2009-01-01

    textabstractThis study examines the relationship between knowledge management (KM) (in terms of external acquisition and internal sharing) and innovation behavior. The concept of absorptive capacity and assumptions from the dynamic capabilities view underlie the proposed framework and hypotheses.

  20. Market Regulators of Service Spheres Innovative Development as a Tool of Regional Socio-Economic Policy

    OpenAIRE

    Pugacheva, Anna S.; Filippova, Viktoriya P.; Kon, Andrei Y.; Dorzhieva, Lyudmila B.; Silchenok, Igor S.; Pugacheva, Natalya B.; Lunev, Alexander N.; Mustafina, Alfiya A.

    2016-01-01

    The relevance of the study is conditioned by the innovative development of service spheres as the reduction of territorial social and economic differentiation to the level, due to objective differences of the regions and to balance of their revenue base and expenditure commitments. The service sector is one of the most dynamic and growing segments of regional markets and one of the characteristics of effective socio-economic policy in the region. Innovative development of service spheres as a...

  1. Innovative Approaches to Development and Ground Testing of Advanced Bimodal Space Power and Propulsion Systems

    International Nuclear Information System (INIS)

    Hill, T.; Noble, C.; Martinell, J.; Borowski, S.

    2000-01-01

    The last major development effort for nuclear power and propulsion systems ended in 1993. Currently, there is not an initiative at either the National Aeronautical and Space Administration (NASA) or the U.S. Department of Energy (DOE) that requires the development of new nuclear power and propulsion systems. Studies continue to show nuclear technology as a strong technical candidate to lead the way toward human exploration of adjacent planets or provide power for deep space missions, particularly a 15,000 lbf bimodal nuclear system with 115 kW power capability. The development of nuclear technology for space applications would require technology development in some areas and a major flight qualification program. The last major ground test facility considered for nuclear propulsion qualification was the U.S. Air Force/DOE Space Nuclear Thermal Propulsion Project. Seven years have passed since that effort, and the questions remain the same, how to qualify nuclear power and propulsion systems for future space flight. It can be reasonably assumed that much of the nuclear testing required to qualify a nuclear system for space application will be performed at DOE facilities as demonstrated by the Nuclear Rocket Engine Reactor Experiment (NERVA) and Space Nuclear Thermal Propulsion (SNTP) programs. The nuclear infrastructure to support testing in this country is aging and getting smaller, though facilities still exist to support many of the technology development needs. By renewing efforts, an innovative approach to qualifying these systems through the use of existing facilities either in the U.S. (DOE's Advance Test Reactor, High Flux Irradiation Facility and the Contained Test Facility) or overseas should be possible

  2. Innovation Approaches to Development and Ground Testing of Advanced Bimodal Space Power and Propulsion Systems

    Energy Technology Data Exchange (ETDEWEB)

    Hill, T.; Noble, C.; Martinell, J. (INEEL); Borowski, S. (NASA Glenn Research Center)

    2000-07-14

    The last major development effort for nuclear power and propulsion systems ended in 1993. Currently, there is not an initiative at either the National Aeronautical and Space Administration (NASA) or the U.S. Department of Energy (DOE) that requires the development of new nuclear power and propulsion systems. Studies continue to show nuclear technology as a strong technical candidate to lead the way toward human exploration of adjacent planets or provide power for deep space missions, particularly a 15,000 lbf bimodal nuclear system with 115 kW power capability. The development of nuclear technology for space applications would require technology development in some areas and a major flight qualification program. The last major ground test facility considered for nuclear propulsion qualification was the U.S. Air Force/DOE Space Nuclear Thermal Propulsion Project. Seven years have passed since that effort, and the questions remain the same, how to qualify nuclear power and propulsion systems for future space flight. It can be reasonably assumed that much of the nuclear testing required to qualify a nuclear system for space application will be performed at DOE facilities as demonstrated by the Nuclear Rocket Engine Reactor Experiment (NERVA) and Space Nuclear Thermal Propulsion (SNTP) programs. The nuclear infrastructure to support testing in this country is aging and getting smaller, though facilities still exist to support many of the technology development needs. By renewing efforts, an innovative approach to qualifying these systems through the use of existing facilities either in the U.S. (DOE's Advance Test Reactor, High Flux Irradiation Facility and the Contained Test Facility) or overseas should be possible.

  3. Innovative Approaches to Development and Ground Testing of Advanced Bimodal Space Power and Propulsion Systems

    Energy Technology Data Exchange (ETDEWEB)

    Hill, Thomas Johnathan; Noble, Cheryl Ann; Noble, C.; Martinell, John Stephen; Borowski, S.

    2000-07-01

    The last major development effort for nuclear power and propulsion systems ended in 1993. Currently, there is not an initiative at either the National Aeronautical and Space Administration (NASA) or the U.S. Department of Energy (DOE) that requires the development of new nuclear power and propulsion systems. Studies continue to show nuclear technology as a strong technical candidate to lead the way toward human exploration of adjacent planets or provide power for deep space missions, particularly a 15,000 lbf bimodal nuclear system with 115 kW power capability. The development of nuclear technology for space applications would require technology development in some areas and a major flight qualification program. The last major ground test facility considered for nuclear propulsion qualification was the U.S. Air Force/DOE Space Nuclear Thermal Propulsion Project. Seven years have passed since that effort, and the questions remain the same, how to qualify nuclear power and propulsion systems for future space flight. It can be reasonable assumed that much of the nuclear testing required to qualify a nuclear system for space application will be performed at DOE facilities as demonstrated by the Nuclear Rocket Engine Reactor Experiment (NERVA) and Space Nuclear Thermal Propulsion (SNTP) programs. The nuclear infrastructure to support testing in this country is aging and getting smaller, though facilities still exist to support many of the technology development needs. By renewing efforts, an innovative approach to qualifying these systems through the use of existing facilities either in the U.S. (DOE's Advance Test Reactor, High Flux Irradiation Facility and the Contained Test Facility) or overseas should be possible.

  4. Advancement of Tools Supporting Improvement of Work Safety in Selected Industrial Company

    Science.gov (United States)

    Gembalska-Kwiecień, Anna

    2018-03-01

    In the presented article, the advancement of tools to improve the safety of work in the researched industrial company was taken into consideration. Attention was paid to the skillful analysis of the working environment, which includes the available technologies, work organization and human capital. These factors determine the development of the best prevention activities to minimize the number of accidents.

  5. AVATAR: AdVanced Aerodynamic Tools for lArge Rotors

    DEFF Research Database (Denmark)

    Schepers, J.C.; Ceyhan, O.; Savenije, F.J.

    2015-01-01

    An EERA (European Energy Research Alliance) consortium started an ambitious EU FP7 project AVATAR (AdVanced Aerodynamic Tools of lArge Rotors) in November 2013. The project lasts 4 years and is carried out in a consortium with 11 research institutes and two industry partners. The motivation...

  6. Next-Generation Entrepreneurs Ready to Advance Breast Cancer Research Innovations | Poster

    Science.gov (United States)

    By Michele Newton and Thomas Stackhouse, Contributing Writers, and Rosemarie Truman, Guest Writer Editor’s note: In May 2014, the Breast Cancer Start-Up Challenge was named one of six finalists in the HHS Innovates Award Competition. This award celebrates innovations developed by employees of the U.S. Department of Health and Human Services (HHS) to support the mission of HHS.

  7. Virtual reality in advanced medical immersive imaging: a workflow for introducing virtual reality as a supporting tool in medical imaging

    KAUST Repository

    Knodel, Markus M.

    2018-02-27

    Radiologic evaluation of images from computed tomography (CT) or magnetic resonance imaging for diagnostic purposes is based on the analysis of single slices, occasionally supplementing this information with 3D reconstructions as well as surface or volume rendered images. However, due to the complexity of anatomical or pathological structures in biomedical imaging, innovative visualization techniques are required to display morphological characteristics three dimensionally. Virtual reality is a modern tool of representing visual data, The observer has the impression of being “inside” a virtual surrounding, which is referred to as immersive imaging. Such techniques are currently being used in technical applications, e.g. in the automobile industry. Our aim is to introduce a workflow realized within one simple program which processes common image stacks from CT, produces 3D volume and surface reconstruction and rendering, and finally includes the data into a virtual reality device equipped with a motion head tracking cave automatic virtual environment system. Such techniques have the potential to augment the possibilities in non-invasive medical imaging, e.g. for surgical planning or educational purposes to add another dimension for advanced understanding of complex anatomical and pathological structures. To this end, the reconstructions are based on advanced mathematical techniques and the corresponding grids which we can export are intended to form the basis for simulations of mathematical models of the pathogenesis of different diseases.

  8. COINS: An innovative informatics and neuroimaging tool suite built for large heterogeneous datasets

    Directory of Open Access Journals (Sweden)

    Adam eScott

    2011-12-01

    Full Text Available The availability of well-characterized neuroimaging data with large numbers of subjects, especially for clinical populations, is critical to advancing our understanding of the healthy and diseased brain. Such data enables questions to be answered in a much more generalizable manner and also has the potential to yield solutions derived from novel methods that were conceived after the original studies' implementation. Though there is currently growing interest in data sharing, the neuroimaging community has been struggling for years with how to best encourage sharing data across brain imaging studies. With the advent of studies that are much more consistent across sites (e.g., resting fMRI, diffusion tensor imaging, and structural imaging the potential of pooling data across studies continues to gain momentum.At the Mind Research Network (MRN, we have developed the COllaborative Informatics and Neuroimaging Suite (COINS; http://coins.mrn.org to provide researchers with an information system based on an open-source model that includes web-based tools to manage studies, subjects, imaging, clinical data and other assessments. The system currently hosts data from 9 institutions, over 300 studies, over 14,000 subjects, and over 19,000 MRI, MEG, and EEG scan sessions in addition to more than 180,000 clinical assessments. In this paper we provide a description of COINS with comparison to a valuable and popular system known as XNAT. Although there are many similarities between COINS and other electronic data management systems, the differences that may concern researchers in the context of multi-site, multi-organizational data-sharing environments with intuitive ease of use and PHI security are emphasized as important attributes.

  9. Collaborative innovation as a tool for environmental, economic and social sustainability in regional governance

    DEFF Research Database (Denmark)

    Torfing, Jacob; Hofstad, Hege

    2015-01-01

    solutions to common problems. The paper analyses the efforts of Norwegian regions to enhance collaborative innovation through the formation of interactive governance arenas. It compares three different policy areas in order to better understand how different forms of interactive governance enhance...... collaborative innovation for economic, social and environmental sustainability. The ultimate goal is to assess the ability and potential of Norwegian regions to solve wicked and unruly problems through collaborative innovation.......In the Scandinavian countries, the regional level of governance is neither the locus of large-scale policy reforms nor a significant provider of welfare to citizens. Nevertheless, it has some important policy tasks in the area of environmental, economic, and social sustainability. These policy...

  10. An empowerment-based approach to developing innovative e-health tools for self-management

    NARCIS (Netherlands)

    Alpay, L.; Boog, P. van der; Dumaij, A.

    2011-01-01

    E-health is seen as an important technological tool in achieving self-management; however, there is little evidence of how effective e-health is for self-management. Example tools remain experimental and there is limited knowledge yet about the design, use, and effects of this class of tools. By way

  11. Innovative tools for business coalitions in B2B applications how negotiation, auction and game theory can support small- and medium-sized business in e-business

    CERN Document Server

    Argoneto, Pierluigi

    2011-01-01

    Discussion of how to implement innovative tools makes the book relevant to both researchers and managers The simulation environment allows the reader to evaluate the performance of the approaches proposed Includes methodologies to improve e-marketplace performances through coalition

  12. Advancing tuberculosis drug regimen development through innovative quantitative translational pharmacology methods and approaches.

    Science.gov (United States)

    Hanna, Debra; Romero, Klaus; Schito, Marco

    2017-03-01

    The development of novel tuberculosis (TB) multi-drug regimens that are more efficacious and of shorter duration requires a robust drug development pipeline. Advances in quantitative modeling and simulation can be used to maximize the utility of patient-level data from prior and contemporary clinical trials, thus optimizing study design for anti-TB regimens. This perspective article highlights the work of seven project teams developing first-in-class translational and quantitative methodologies that aim to inform drug development decision-making, dose selection, trial design, and safety assessments, in order to achieve shorter and safer therapies for patients in need. These tools offer the opportunity to evaluate multiple hypotheses and provide a means to identify, quantify, and understand relevant sources of variability, to optimize translation and clinical trial design. When incorporated into the broader regulatory sciences framework, these efforts have the potential to transform the development paradigm for TB combination development, as well as other areas of global health. Copyright © 2016. Published by Elsevier Ltd.

  13. Volpe Center Annual Accomplishments: Advancing Transportation Innovation for the Public Good - January 2018

    Science.gov (United States)

    2018-01-01

    The Volpe Centers Annual Accomplishments highlights our best work of 2017 and illustrates the sustained impact of the Volpe Center in supporting the U.S. DOTs top priorities and strategic goals: safety, infrastructure, innovation, and accountab...

  14. LCA as a Tool for Assessing Product and Process Oriented Eco-Innovations Undertaken by Enterprises

    Directory of Open Access Journals (Sweden)

    Rybaczewska-Błażejowska Magdalena

    2017-09-01

    Full Text Available This paper examines the application of life cycle assessment (LCA as an approach to foster the product and process oriented eco- innovation of enterprises, using the fruit and vegetable processing plant as an example. LCA, which is traditionally used to assess the impacts of a single product system on the environment, was applied in the enterprise context. This was made possible by forming an indicator describing the environmental profile of an enterprise, which is calculated by the sum of the multiplication of the environmental impact assessment (LCIA results for individual unit processes within a particular impact category and their weights reflecting the structure of production in an enterprise. In order to distinguish and indicate the direction in which an enterprise should undertake its eco-innovative actions (implementing eco-innovations within the product or production process the LCIA results are presented individually for products and production processes. The research was conducted in full compliance with the LCA methodology. LCA proved that the analysed enterprise has the largest negative impacts on the environment in the following impact categories: marine eco-toxicity, freshwater eco-toxicity, freshwater eutrophication, human toxicity and natural land transformation. They result primarily from the consumption of thermal and electric energy in the production processes. Therefore, to improve energy efficiency, the enterprise should take eco-innovative actions in the processes applied.

  15. Russian National Corpus as a Tool of Linguo-Didactic Innovation in Teaching Languages

    Science.gov (United States)

    Ponomareva, Lyubov Dmitrievna; Churilina, Lyubov Nikolaevna; Buzhinskaya, Darya Sergeyevna; Derevskova, Elena Nikolayevna; Dorfman, Oksana Vyacheslavovna; Sokolova, Elena Petrovna

    2016-01-01

    Emphasis on universal learning activities of each student rather than acquisition of ready knowledge, as well as on how an individual masters a language necessitate the development and application of innovative technologies promoting functional-semantic and textual approaches. In the modern context, Russian language teachers, along with knowledge…

  16. Redefining responsible research and innovation for the advancement of biobanking and biomedical research.

    Science.gov (United States)

    Yu, Helen

    2016-12-01

    One of the core objectives of responsible research and innovation (RRI) is to maximize the value of publicly funded research so that it may be returned to benefit society. However, while RRI encourages innovation through societal engagement, it can give rise to complex and previously untested issues that challenge the existing legal frameworks on intellectual property (IP) and public entitlement to benefits of research. In the case of biobanking, the personal nature of human biological materials and often altruistic intention of participants to donate samples intensifies the need to adhere to RRI principles with respect to the research, development, and commercialization of innovations derived from biobanks. However, stakeholders participate and collaborate with others in the innovation process to fulfill their own agenda. Without IP to safeguard investments in R&D, stakeholders may hesitate to contribute to the translation of discoveries into innovations. To realize the public benefit objective, RRI principles must protect the interests of stakeholders involved in the translation and commercialization of knowledge. This article explores the seemingly contradictory and competing objectives of open science and commercialization and proposes a holistic innovation framework directed at improving RRI practice for positive impact on obtaining the optimal social and economic values from research.

  17. 5th Conference on Advanced Mathematical and Computational Tools in Metrology

    CERN Document Server

    Cox, M G; Filipe, E; Pavese, F; Richter, D

    2001-01-01

    Advances in metrology depend on improvements in scientific and technical knowledge and in instrumentation quality, as well as on better use of advanced mathematical tools and development of new ones. In this volume, scientists from both the mathematical and the metrological fields exchange their experiences. Industrial sectors, such as instrumentation and software, will benefit from this exchange, since metrology has a high impact on the overall quality of industrial products, and applied mathematics is becoming more and more important in industrial processes.This book is of interest to people

  18. Current Research on Containment Technologies for Verification Activities: Advanced Tools for Maintaining Continuity of Knowledge

    International Nuclear Information System (INIS)

    Smartt, H.; Kuhn, M.; Krementz, D.

    2015-01-01

    The U.S. National Nuclear Security Administration (NNSA) Office of Non-proliferation and Verification Research and Development currently funds research on advanced containment technologies to support Continuity of Knowledge (CoK) objectives for verification regimes. One effort in this area is the Advanced Tools for Maintaining Continuity of Knowledge (ATCK) project. Recognizing that CoK assurances must withstand potential threats from sophisticated adversaries, and that containment options must therefore keep pace with technology advances, the NNSA research and development on advanced containment tools is an important investment. The two ATCK efforts underway at present address the technical containment requirements for securing access points (loop seals) and protecting defined volumes. Multiple U.S. national laboratories are supporting this project: Sandia National Laboratories (SNL), Savannah River National Laboratory (SRNL), and Oak Ridge National Laboratory (ORNL). SNL and SRNL are developing the ''Ceramic Seal,'' an active loop seal that integrates multiple advanced security capabilities and improved efficiency housed within a small-volume ceramic body. The development includes an associated handheld reader and interface software. Currently at the prototype stage, the Ceramic Seal will undergo a series of tests to determine operational readiness. It will be field tested in a representative verification trial in 2016. ORNL is developing the Whole Volume Containment Seal (WCS), a flexible conductive fabric capable of enclosing various sizes and shapes of monitored items. The WCS includes a distributed impedance measurement system for imaging the fabric surface area and passive tamper-indicating features such as permanent-staining conductive ink. With the expected technology advances from the Ceramic Seal and WCS, the ATCK project takes significant steps in advancing containment technologies to help maintain CoK for various verification

  19. Provider Tools for Advance Care Planning and Goals of Care Discussions: A Systematic Review.

    Science.gov (United States)

    Myers, Jeff; Cosby, Roxanne; Gzik, Danusia; Harle, Ingrid; Harrold, Deb; Incardona, Nadia; Walton, Tara

    2018-01-01

    Advance care planning and goals of care discussions involve the exploration of what is most important to a person, including their values and beliefs in preparation for health-care decision-making. Advance care planning conversations focus on planning for future health care, ensuring that an incapable person's wishes are known and can guide the person's substitute decision maker for future decision-making. Goals of care discussions focus on preparing for current decision-making by ensuring the person's goals guide this process. To provide evidence regarding tools and/or practices available for use by health-care providers to effectively facilitate advance care planning conversations and/or goals of care discussions. A systematic review was conducted focusing on guidelines, randomized trials, comparative studies, and noncomparative studies. Databases searched included MEDLINE, EMBASE, and the proceedings of the International Advance Care Planning Conference and the American Society of Clinical Oncology Palliative Care Symposium. Although several studies report positive findings, there is a lack of consistent patient outcome evidence to support any one clinical tool for use in advance care planning or goals of care discussions. Effective advance care planning conversations at both the population and the individual level require provider education and communication skill development, standardized and accessible documentation, quality improvement initiatives, and system-wide coordination to impact the population level. There is a need for research focused on goals of care discussions, to clarify the purpose and expected outcomes of these discussions, and to clearly differentiate goals of care from advance care planning.

  20. Bacteriophage-based tools: recent advances and novel applications [version 1; referees: 3 approved

    Directory of Open Access Journals (Sweden)

    Lisa O'Sullivan

    2016-11-01

    Full Text Available Bacteriophages (phages are viruses that infect bacterial hosts, and since their discovery over a century ago they have been primarily exploited to control bacterial populations and to serve as tools in molecular biology. In this commentary, we highlight recent diverse advances in the field of phage research, going beyond bacterial control using whole phage, to areas including biocontrol using phage-derived enzybiotics, diagnostics, drug discovery, novel drug delivery systems and bionanotechnology.

  1. The categorization of the impacts of the results of scientific and technological innovation in the Agency of Nuclear energy and advanced technologies (AENTA)

    International Nuclear Information System (INIS)

    Rodriguez Cardona, R.; Cobas Aranda, M.

    2010-01-01

    Science and technology are essential to the development of contemporary societies, however, there are different concepts and methodologies internationally to assess the economic and social impact of science and technology. In our country he has worked intensely with this aim and has established a national nomenclature of impact of science, technology and innovation. The Agency of Nuclear energy and advanced technologies (AEN-TA) is intended to improve the management of the programmes and projects management system framed within the system of science and technological innovation of the Republic of Cuba (SCIT) and one of the aspects of your special attention is the proper selection and follow-up (ex - before and during) projects to ensure that they contribute to improving the level of economic and social of our country one of his fundamental premises. This work has aims to show how the bases of the categorization of the impacts of the projects were established in the AEN-Mt management programs, as a management tool for the selection and monitoring of them, and which are characterized by a flexibility that keeping their identity do not differ from the established in the country. (author)

  2. Knowledge Management as a Strategic Tool to Foster Innovativeness of SMEs

    OpenAIRE

    Zhou, Haibo; Uhlaner, Lorraine

    2009-01-01

    textabstractThis study examines the relationship between knowledge management (KM) (in terms of external acquisition and internal sharing) and innovation behavior. The concept of absorptive capacity and assumptions from the dynamic capabilities view underlie the proposed framework and hypotheses. The framework is empirically tested using a random sample of 649 Dutch small to medium sized enterprises (SMEs). Our empricial results indicate that external acquisition practices play a key role in ...

  3. Ethnodrama: An Innovative Knowledge Translation Tool in the Management of Lymphedema

    OpenAIRE

    Ahmed, Shahid; Quinlan, Elizabeth; McMullen, Linda; Thomas, Roanne; Fichtner, Pam; Block, Janice

    2015-01-01

    Background: Lymphedema can cause significant physical impairment and quality-of-life issues. Yet there is a gap in knowledge about lymphedema among breast cancer survivors (BCS), and health care professionals (HCP). Ethnodrama is an innovative knowledge translation strategy that uses theatrical performances for dissemination of research results. We evaluated the impact of live ethnodrama on HCP' and BCS' awareness and attitudes in relation to impact of lymphedema on BCS' lives. Methods: Ethno...

  4. Designing a Business Model for Environmental Monitoring Services Using Fast MCDS Innovation Support Tools

    Directory of Open Access Journals (Sweden)

    Tuomo Eskelinen

    2017-11-01

    Full Text Available The free availability of open data provides opportunities to start new businesses and gain business intelligence. However, although data is often used to support decisions and actions, the possibilities offered by modern sensor technologies with connections to cloud-based data collection services are not being effectively capitalized. Data collection systems are also not generally open source solutions, even though open and flexibly adjustable systems would broaden the opportunities for solutions and larger revenue streams. In this article, we used action research methods to discover new business opportunities in a semi-open information system that utilizes environmental monitoring data. We applied a four-stage innovation process for industry, which included context definition, idea generation, and selection, and produced multi-criteria decision support (MCDS data to help the design of business model. This was done to reveal business opportunities for an environmental monitoring service. Among these opportunities, one service-style business model canvas was identified as feasible and selected for further development. We identified items that are needed in the commercialization process of environmental monitoring services. Our process combines open environmental monitoring data, participative innovation process, and MCDS support, and it supports and accelerates a co-creative business model creation process that is cost-beneficial in terms of saving time. The results are applicable to the creation of an open data information system that supports data-driven innovation.

  5. Innovative Positioning as a Marketing Tool of Retailers on the Food Market

    Directory of Open Access Journals (Sweden)

    Grażyna Śmigielska

    2017-03-01

    Full Text Available Objective: The aim of the paper is to develop the theory of retail business positioning as a part of marketing innovation-based strategy. It is proposed that innovative retail formats and business models should be included in it. Research Design & Methods: The critical literature review on the existing dimensions of business positioning as well as the new, suggested dimensions is made. General trends in food retailers’ positioning in Poland and the positioning strategy development of Carrefour are analysed in the form of examples and a short case study. They are based on the secondary sources like academic papers, retail magazines and companies’ web sites. Findings: On the fragmented food markets retailers position themselves by introducing format innovations and stressing low price. Then they have to reposition themselves by attributes other than price. Big mass merchandisers are now segmenters. Implications & Recommendations: In Poland the tendencies for buying natural, Fair Trade, diabetics, organic or functional products, as well as the focus on the elderly segment are opportunities for retailers. Yet, trading up creates new opportunities for discounters. Contribution & Value Added: The paper contributes to the theory of retail positioning by linking elements of the marketing and the entrepreneurship approaches. It also develops knowledge about the Polish retail food market.

  6. Innovation in Flight: Research of the NASA Langley Research Center on Revolutionary Advanced Concepts for Aeronautics

    Science.gov (United States)

    Chambers, Joseph R.

    2005-01-01

    The goal of this publication is to provide an overview of the topic of revolutionary research in aeronautics at Langley, including many examples of research efforts that offer significant potential benefits, but have not yet been applied. The discussion also includes an overview of how innovation and creativity is stimulated within the Center, and a perspective on the future of innovation. The documentation of this topic, especially the scope and experiences of the example research activities covered, is intended to provide background information for future researchers.

  7. Accelerating Innovation that Enhances Resource Recovery in the Wastewater Sector: Advancing a National Testbed Network.

    Science.gov (United States)

    Mihelcic, James R; Ren, Zhiyong Jason; Cornejo, Pablo K; Fisher, Aaron; Simon, A J; Snyder, Seth W; Zhang, Qiong; Rosso, Diego; Huggins, Tyler M; Cooper, William; Moeller, Jeff; Rose, Bob; Schottel, Brandi L; Turgeon, Jason

    2017-07-18

    This Feature examines significant challenges and opportunities to spur innovation and accelerate adoption of reliable technologies that enhance integrated resource recovery in the wastewater sector through the creation of a national testbed network. The network is a virtual entity that connects appropriate physical testing facilities, and other components needed for a testbed network, with researchers, investors, technology providers, utilities, regulators, and other stakeholders to accelerate the adoption of innovative technologies and processes that are needed for the water resource recovery facility of the future. Here we summarize and extract key issues and developments, to provide a strategy for the wastewater sector to accelerate a path forward that leads to new sustainable water infrastructures.

  8. Conference Scene: From innovative polymers to advanced nanomedicine: Key challenges, recent progress and future perspectives

    NARCIS (Netherlands)

    Feijen, Jan; Hennink, W.E.; Zhong, Zhiyuan

    2013-01-01

    Recent developments in polymer-based controlled delivery systems have made a significant clinical impact. The second Symposium on Innovative Polymers for Controlled Delivery (SIPCD) was held in Suzhou, China to address the key challenges and provide up-to-date progress and future perspectives in the

  9. Experimental Watershed Study Designs: A Tool for Advancing Process Understanding and Management of Mixed-Land-Use Watersheds

    Science.gov (United States)

    Hubbart, J. A.; Kellner, R. E.; Zeiger, S. J.

    2016-12-01

    Advancements in watershed management are both a major challenge, and urgent need of this century. The experimental watershed study (EWS) approach provides critical baseline and long-term information that can improve decision-making, and reduce misallocation of mitigation investments. Historically, the EWS approach was used in wildland watersheds to quantitatively characterize basic landscape alterations (e.g. forest harvest, road building). However, in recent years, EWS is being repurposed in contemporary multiple-land-use watersheds comprising a mosaic of land use practices such as urbanizing centers, industry, agriculture, and rural development. The EWS method provides scalable and transferrable results that address the uncertainties of development, while providing a scientific basis for total maximum daily load (TMDL) targets in increasing numbers of Clean Water Act 303(d) listed waters. Collaborative adaptive management (CAM) programs, designed to consider the needs of many stakeholders, can also benefit from EWS-generated information, which can be used for best decision making, and serve as a guidance tool throughout the CAM program duration. Of similar importance, long-term EWS monitoring programs create a model system to show stakeholders how investing in rigorous scientific research initiatives improves decision-making, thereby increasing management efficiencies through more focused investments. The evolution from classic wildland EWS designs to contemporary EWS designs in multiple-land-use watersheds will be presented while illustrating how such an approach can encourage innovation, cooperation, and trust among watershed stakeholders working to reach the common goal of improving and sustaining hydrologic regimes and water quality.

  10. Simulation as a tool for developing knowledge mobilisation strategies: Innovative knowledge transfer in youth services

    Directory of Open Access Journals (Sweden)

    Michael Ungar

    2015-09-01

    Full Text Available While there are excellent models of knowledge mobilisation (KMb that address the opportunity for co-production and sharing of best practice knowledge among human service professionals, it remains unclear whether these models will work in less formal settings like community-based non-government organisations (NGOs where there are fewer resources for KMb. For three days, 65 policy-makers, senior staff of NGOs, mental health professionals, KMb specialists and youth participated in a set of simulation exercises to problem solve how to mobilise knowledge in less formal settings that provide services to children and youth in challenging contexts (CYCC. Based on simulation exercises used in other settings (such as the deployment of international aid workers, participants were first provided with reports synthesising best practice knowledge relevant to their workplaces. They then engaged in an appreciative inquiry process, and were finally tasked with developing innovative strategies for KMb. Observation notes and exit interviews were used to evaluate the process and assess impact. Findings related to the process of the simulation exercises show the technique of simulation to be useful but that it requires effort to keep participants focused on the task of KMb rather than the content of best practices within a focal population. With regard to developing innovative KMb strategies, findings suggest that service providers in less formal community-based services prefer KMb activities that promote one-to-one relationships, including the participation of youth themselves, who can speak to the effectiveness of the interventions they have experienced. Unexpectedly, the use of electronic communication, including social media, was not viewed very positively by participants. These results suggest that the use of simulation to search for innovative KMb strategies and to problem solve around barriers to KMb has the potential to inform new ways of co-producing and

  11. Design and field test of collaborative tools in the service of an innovative organization

    International Nuclear Information System (INIS)

    De Beler, N.; Parfouru, S.

    2012-01-01

    This paper presents the design process of collaborative tools, based on ICT, aiming at supporting the tasks of the team that manages an outage of an energy production plant for maintenance activities. The design process follows an iterative and multidisciplinary approach, based on a collective tasks modeling of the outage management team in the light of Socio Organizational and Human (SOH) field studies, and on the state of the art of ICT. Field test of the collaborative tools designed plays a great place in this approach, allowing taking into account the operational world but involves also some risks which must be managed. To implement tools on all the production plants, we build an 'operational concept' with a level of description which authorizes the evolution of tools and allows some local adaptations. The field tests provide lessons on the ICT topics. For examples: the status of the remote access tools, the potential of use of a given information input by an actor for several individual and collective purposes, the actors perception of the tools meaning, and the requirements for supporting the implementation of change. (authors)

  12. Development of the Music Therapy Assessment Tool for Advanced Huntington's Disease: A Pilot Validation Study.

    Science.gov (United States)

    O'Kelly, Julian; Bodak, Rebeka

    2016-01-01

    Case studies of people with Huntington's disease (HD) report that music therapy provides a range of benefits that may improve quality of life; however, no robust music therapy assessment tools exist for this population. Develop and conduct preliminary psychometric testing of a music therapy assessment tool for patients with advanced HD. First, we established content and face validity of the Music Therapy Assessment Tool for Advanced HD (MATA-HD) through focus groups and field testing. Second, we examined psychometric properties of the resulting MATA-HD in terms of its construct validity, internal consistency, and inter-rater and intra-rater reliability over 10 group music therapy sessions with 19 patients. The resulting MATA-HD included a total of 15 items across six subscales (Arousal/Attention, Physical Presentation, Communication, Musical, Cognition, and Psychological/Behavioral). We found good construct validity (r ≥ 0.7) for Mood, Communication Level, Communication Effectiveness, Choice, Social Behavior, Arousal, and Attention items. Cronbach's α of 0.825 indicated good internal consistency across 11 items with a common focus of engagement in therapy. The inter-rater reliability (IRR) Intra-Class Coefficient (ICC) scores averaged 0.65, and a mean intra-rater ICC reliability of 0.68 was obtained. Further training and retesting provided a mean of IRR ICC of 0.7. Preliminary data indicate that the MATA-HD is a promising tool for measuring patient responses to music therapy interventions across psychological, physical, social, and communication domains of functioning in patients with advanced HD. © the American Music Therapy Association 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  13. Inspection, maintenance, and repair of large pumps and piping systems using advanced robotic tools

    International Nuclear Information System (INIS)

    Lewis, R.K.; Radigan, T.M.

    1998-01-01

    Operating and maintaining large pumps and piping systems can be an expensive proposition. Proper inspections and monitoring can reduce costs. This was difficult in the past, since detailed pump inspections could only be performed by disassembly and many portions of piping systems are buried or covered with insulation. Once these components were disassembled, a majority of the cost was already incurred. At that point, expensive part replacement usually took place whether it was needed or not. With the completion of the Pipe Walkertrademark/LIP System and the planned development of the Submersible Walkertrademark, this situation is due to change. The specifications for these inspection and maintenance robots will ensure that. Their ability to traverse both horizontal and vertical, forward and backward, make them unique tools. They will open the door for some innovative approaches to inspection and maintenance of large pumps and piping systems

  14. Anvil Forecast Tool in the Advanced Weather Interactive Processing System (AWIPS)

    Science.gov (United States)

    Barrett, Joe H., III; Hood, Doris

    2009-01-01

    Launch Weather Officers (LWOs) from the 45th Weather Squadron (45 WS) and forecasters from the National Weather Service (NWS) Spaceflight Meteorology Group (SMG) have identified anvil forecasting as one of their most challenging tasks when predicting the probability of violating the Lightning Launch Commit Criteria (LLCC) (Krider et al. 2006; Space Shuttle Flight Rules (FR), NASA/JSC 2004)). As a result, the Applied Meteorology Unit (AMU) developed a tool that creates an anvil threat corridor graphic that can be overlaid on satellite imagery using the Meteorological Interactive Data Display System (MIDDS, Short and Wheeler, 2002). The tool helps forecasters estimate the locations of thunderstorm anvils at one, two, and three hours into the future. It has been used extensively in launch and landing operations by both the 45 WS and SMG. The Advanced Weather Interactive Processing System (AWIPS) is now used along with MIDDS for weather analysis and display at SMG. In Phase I of this task, SMG tasked the AMU to transition the tool from MIDDS to AWIPS (Barrett et aI., 2007). For Phase II, SMG requested the AMU make the Anvil Forecast Tool in AWIPS more configurable by creating the capability to read model gridded data from user-defined model files instead of hard-coded files. An NWS local AWIPS application called AGRID was used to accomplish this. In addition, SMG needed to be able to define the pressure levels for the model data, instead of hard-coding the bottom level as 300 mb and the top level as 150 mb. This paper describes the initial development of the Anvil Forecast Tool for MIDDS, followed by the migration of the tool to AWIPS in Phase I. It then gives a detailed presentation of the Phase II improvements to the AWIPS tool.

  15. Highlights from the 2015 WIN Symposium: novel targets, innovative agents, and advanced technologies-a WINning strategy?

    Science.gov (United States)

    Schilsky, Richard L

    2015-01-01

    The worldwide innovative networking (WIN) consortium comprises a global alliance of 28 academic and clinical cancer centres, 11 pharmaceutical and technology companies and five charitable or health payer organisations. Since its inception the consortium has striven to provide a forum for all of its members to network, share information and experience, and perform clinical trials with the overarching goal of advancing the care of patients with cancer through the use of precision medicine. The annual 2-day WIN Symposium is the most visible output of the consortium and provides an opportunity for around 400 experts and other delegates to meet and discuss the latest research and initiatives in personalised cancer medicine. The seventh WIN Symposium, held in Paris, France, 29-30 June 2015, consisted of nine plenary and eight poster sessions that covered the overarching theme of novel targets, innovative agents, and advanced technologies being a winning strategy. Highlights included discussions of immune mechanisms and ways to target the cancer immunome and systems biology approaches to supporting personalised cancer. The latest data from the BATTLE-2 and WINther trials were discussed, and round table discussions were held that focused on how best to design the next generation of clinical trials, which included SPRING, SUMMER, and BOOSTER being initiated by the WIN Consortium.

  16. Evolution of the Pediatric Advanced Life Support course: enhanced learning with a new debriefing tool and Web-based module for Pediatric Advanced Life Support instructors.

    Science.gov (United States)

    Cheng, Adam; Rodgers, David L; van der Jagt, Élise; Eppich, Walter; O'Donnell, John

    2012-09-01

    To describe the history of the Pediatric Advanced Life Support course and outline the new developments in instructor training that will impact the way debriefing is conducted during Pediatric Advanced Life Support courses. The Pediatric Advanced Life Support course, first released by the American Heart Association in 1988, has seen substantial growth and change over the past few decades. Over that time, Pediatric Advanced Life Support has become the standard for resuscitation training for pediatric healthcare providers in North America. The incorporation of high-fidelity simulation-based learning into the most recent version of Pediatric Advanced Life Support has helped to enhance the realism of scenarios and cases, but has also placed more emphasis on the importance of post scenario debriefing. We developed two new resources: an online debriefing module designed to introduce a new model of debriefing and a debriefing tool for real-time use during Pediatric Advanced Life Support courses, to enhance and standardize the quality of debriefing by Pediatric Advanced Life Support instructors. In this article, we review the history of Pediatric Advanced Life Support and Pediatric Advanced Life Support instructor training and discuss the development and implementation of the new debriefing module and debriefing tool for Pediatric Advanced Life Support instructors. The incorporation of the debriefing module and debriefing tool into the 2011 Pediatric Advanced Life Support instructor materials will help both new and existing Pediatric Advanced Life Support instructors develop and enhance their debriefing skills with the intention of improving the acquisition of knowledge and skills for Pediatric Advanced Life Support students.

  17. Development of an innovative uav-mounted screening tool for landfill gas emissions

    DEFF Research Database (Denmark)

    Fjelsted, Lotte; Thomasen, T. B.; Valbjørn, I. L.

    2015-01-01

    Identification of landfill gas emission hot spots are potentially a very time consuming process, and the use of an Unmanned Aerial Vehicle (UAV) based screening tool could be an effective investigation strategy. In this study, the potential use of a long-wave thermal infrared camera was investiga......Identification of landfill gas emission hot spots are potentially a very time consuming process, and the use of an Unmanned Aerial Vehicle (UAV) based screening tool could be an effective investigation strategy. In this study, the potential use of a long-wave thermal infrared camera...

  18. An Assessment Tool applied to Manure Management Systems using Innovative Technologies

    DEFF Research Database (Denmark)

    Sørensen, Claus Aage Grøn; Jacobsen, B.H.; Sommer, Sven Gjedde

    2003-01-01

    of operational and cost-effective animal manure handling technologies. An assessment tool covering the whole chain of the manure handling system from the animal houses to the field has been developed. The tool enables a system-oriented evaluation of labour demand, machinery capacity and costs related......In Denmark, stringent new regulations, placing strict time limits on manure application and setting thresholds for nitrogen utilisation, have been imposed in order to increase the efficiency of uptake of plant nutrients from manure. An important factor in meeting these requirements is the use...

  19. Electronic nose as an innovative tool for the diagnosis of grapevine crown gall

    Energy Technology Data Exchange (ETDEWEB)

    Blasioli, S., E-mail: sonia.blasioli@unibo.it [Dipartimento di Scienze e Tecnologie Agroambientali, Universita di Bologna, V.le Fanin, 44, 40127 Bologna (Italy); Biondi, E., E-mail: erbiondi@tin.it [Dipartimento di Scienze e Tecnologie Agroambientali, Universita di Bologna, V.le Fanin, 44, 40127 Bologna (Italy); Braschi, I., E-mail: ilaria.braschi@unibo.it [Dipartimento di Scienze e Tecnologie Agroambientali, Universita di Bologna, V.le Fanin, 44, 40127 Bologna (Italy); Mazzucchi, U., E-mail: umberto.mazzucchi@unibo.it [Dipartimento di Scienze e Tecnologie Agroambientali, Universita di Bologna, V.le Fanin, 44, 40127 Bologna (Italy); Bazzi, C., E-mail: carlo.bazzi@unibo.it [Dipartimento di Scienze e Tecnologie Agroambientali, Universita di Bologna, V.le Fanin, 44, 40127 Bologna (Italy); Gessa, C.E., E-mail: carloemanuele.gessa@unibo.it [Dipartimento di Scienze e Tecnologie Agroambientali, Universita di Bologna, V.le Fanin, 44, 40127 Bologna (Italy)

    2010-07-05

    For the first time, a portable electronic nose was used to discriminate between healthy and galled grapevines, experimentally inoculated with two tumourigenic strains of Agrobacterium vitis. The volatile profile of target cutting samples was analysed by headspace solid phase microextraction coupled with gas chromatography-mass spectrometry. Spectra from tumoured samples revealed the presence of styrene which is compatible with decarboxylation of cinnamic acid involved in secondary metabolism of plants. Principal Component Analysis confirmed the difference in volatile profiles of infected vines and their healthy controls. Linear Discriminant Analysis allowed the correct discrimination between healthy and galled grapevines (83.3%, cross-validation). Although a larger number of samples should be analysed to create a more robust model, our results give novel interesting clues to go further with research on the diagnostic potential of this innovative system associated with multi-dimensional chemometric techniques.

  20. Innovative analytical tools to characterize prebiotic carbohydrates of functional food interest.

    Science.gov (United States)

    Corradini, Claudio; Lantano, Claudia; Cavazza, Antonella

    2013-05-01

    Functional foods are one of the most interesting areas of research and innovation in the food industry. A functional food or functional ingredient is considered to be any food or food component that provides health benefits beyond basic nutrition. Recently, consumers have shown interest in natural bioactive compounds as functional ingredients in the diet owing to their various beneficial effects for health. Water-soluble fibers and nondigestible oligosaccharides and polysaccharides can be defined as functional food ingredients. Fructooligosaccharides (FOS) and inulin are resistant to direct metabolism by the host and reach the caecocolon, where they are used by selected groups of beneficial bacteria. Furthermore, they are able to improve physical and structural properties of food, such as hydration, oil-holding capacity, viscosity, texture, sensory characteristics, and shelf-life. This article reviews major innovative analytical developments to screen and identify FOS, inulins, and the most employed nonstarch carbohydrates added or naturally present in functional food formulations. High-performance anion-exchange chromatography with pulsed electrochemical detection (HPAEC-PED) is one of the most employed analytical techniques for the characterization of those molecules. Mass spectrometry is also of great help, in particularly matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), which is able to provide extensive information regarding the molecular weight and length profiles of oligosaccharides and polysaccharides. Moreover, MALDI-TOF-MS in combination with HPAEC-PED has been shown to be of great value for the complementary information it can provide. Some other techniques, such as NMR spectroscopy, are also discussed, with relevant examples of recent applications. A number of articles have appeared in the literature in recent years regarding the analysis of inulin, FOS, and other carbohydrates of interest in the field and

  1. WATERPROTECT: Innovative tools enabling drinking water protection in rural and urban environments

    Science.gov (United States)

    Seuntjens, Piet; Campling, Paul; Joris, Ingeborg; Wauters, Erwin; Lopez de Alda, Miren; Kuczynska, Anna; Lajer Hojberg, Anker; Capri, Ettore; Brabyn, Cristina; Boeckaert, Charlotte; Mellander, Per Erik; Pauwelyn, Ellen; Pop, Edit

    2017-04-01

    High-quality, safe, and sufficient drinking water is essential for life: we use it for drinking, food preparation and cleaning. Agriculture is the biggest source of pesticides and nitrate pollution in European fresh waters. The overarching objective of the recently approved H2020 project WATERPROTECT is to contribute to effective uptake and realisation of management practices and mitigation measures to protect drinking water resources. Therefore WATERPROTECT will create an integrative multi-actor participatory framework including innovative instruments that enable actors to monitor, to finance and to effectively implement management practices and measures for the protection of water sources. We propose seven case studies involving multiple actors in implementing good practices (land management, farming, product stewardship, point source pollution prevention) to ensure safe drinking water supply. The seven case studies cover different pedo-climatic conditions, different types of farming systems, different legal frameworks, larger and smaller water collection areas across the EU. In close cooperation with actors in the field in the case studies (farmers associations, local authorities, water producing companies, private water companies, consumer organisations) and other stakeholders (fertilizer and plant protection industry, environment agencies, nature conservation agencies, agricultural administrations) at local and EU level, WATERPROTECT will develop innovative water governance models investigating alternative pathways from focusing on the 'costs of water treatment' to 'rewarding water quality delivering farming systems'. Water governance structures will be built upon cost-efficiency analysis related to mitigation and cost-benefit analysis for society, and will be supported by spatially explicit GIS analyses and predictive models that account for temporal and spatial scaling issues. The outcome will be improved participatory methods and public policy instruments

  2. iMindMap as an Innovative Tool in Teaching and Learning Accounting: An Exploratory Study

    Science.gov (United States)

    Wan Jusoh, Wan Noor Hazlina; Ahmad, Suraya

    2016-01-01

    Purpose: The purpose of this study is to explore the use of iMindMap software as an interactive tool in the teaching and learning method and also to be able to consider iMindMap as an alternative instrument in achieving the ultimate learning outcome. Design/Methodology/Approach: Out of 268 students of the management accounting at the University of…

  3. Laser Pointers: Low-Cost, Low-Tech Innovative, Interactive Instruction Tool

    Science.gov (United States)

    Zdravkovska, Nevenka; Cech, Maureen; Beygo, Pinar; Kackley, Bob

    2010-01-01

    This paper discusses the use of laser pointers at the Engineering and Physical Sciences Library, University of Maryland, College Park, as a personal response system (PRS) tool to encourage student engagement in and interactivity with one-shot, lecture-based information literacy sessions. Unlike more sophisticated personal response systems like…

  4. QChain - integrating social, environmental and economic value: a tool to support innovation in production chains

    NARCIS (Netherlands)

    Kassahun, A.; Chatenier, du E.; Bots, P.W.G.; Hofstede, Gert Jan; Bloemhof, J.M.; Scholten, H.; Korver, S.; Beulens, A.J.M.

    2011-01-01

    Today's consumers increasingly demand products that are produced sustainably and ethically. As a result, businesses need to address sustainability and social responsibility issues and find a proper balance between people, planet and profit (PPP) aspects of their production chains. Software tools can

  5. Design-Thinking, Making, and Innovating: Fresh Tools for the Physician's Toolbox

    Science.gov (United States)

    Albala, L.; Bober, T.; Mallozzi, M.; Koeneke-Hernandez, L.; Ku, B.

    2018-01-01

    Medical school education should foster creativity by enabling students to become "makers" who prototype and design. Healthcare professionals and students experience pain points on a daily basis, but are not given the tools, training, or opportunity to help solve them in new, potentially better ways. The student physician of the future…

  6. The Human Rights Key: An innovative tool for teaching health and ...

    African Journals Online (AJOL)

    I propose the Human Rights Key as a useful visual communication tool to guide students in connecting their classroom learning with the reality of local, regional and international health and human rights issues. As an OER with a Creative Commons licence, the Key is available online for both educators and students to use ...

  7. A framework for evaluating innovative statistical and risk assessment tools to solve environment restoration problems

    International Nuclear Information System (INIS)

    Hassig, N.L.; Gilbert, R.O.; Pulsipher, B.A.

    1991-09-01

    Environmental restoration activities at the US Department of Energy (DOE) Hanford site face complex issues due to history of varied past contaminant disposal practices. Data collection and analysis required for site characterization, pathway modeling, and remediation selection decisions must deal with inherent uncertainties and unique problems associated with the restoration. A framework for working through the statistical aspects of the site characterization and remediation selection problems is needed. This framework would facilitate the selection of appropriate statistical tools for solving unique aspects of the environmental restoration problem. This paper presents a framework for selecting appropriate statistical and risk assessment methods. The following points will be made: (1) pathway modelers and risk assessors often recognize that ''some type'' of statistical methods are required but don't work with statisticians on tools development in the early planning phases of the project; (2) statistical tools selection and development are problem-specific and often site-specific, further indicating a need for up-front involvement of statisticians; and (3) the right tool, applied in the right way can minimize sampling costs, get as much information as possible out of the data that does exist, provide consistency and defensibility for the results, and given structure and quantitative measures to decision risks and uncertainties

  8. IdeMatch – a digital tool for innovative, social and transdisciplinary learning designs

    DEFF Research Database (Denmark)

    Hansen, Gitte Riis

    This paper presents IdeMatch which is a digital tool implemented in University College Zealand (UCZ) in spring 2015. IdeMatch is based on educational policies and educational structural intentions and needs, and this paper examines and offers an outline for the learning perspective and the impact...... that IdeMatch has got concerning teaching and learning designs....

  9. Innovative Stormwater Quality Tools by SARA for Holistic Watershed Master Planning

    Science.gov (United States)

    Thomas, S. M.; Su, Y. C.; Hummel, P. R.

    2016-12-01

    Stormwater management strategies such as Best Management Practices (BMP) and Low-Impact Development (LID) have increasingly gained attention in urban runoff control, becoming vital to holistic watershed master plans. These strategies can help address existing water quality impairments and support regulatory compliance, as well as guide planning and management of future development when substantial population growth and urbanization is projected to occur. However, past efforts have been limited to qualitative planning due to the lack of suitable tools to conduct quantitative assessment. The San Antonio River Authority (SARA), with the assistance of Lockwood, Andrews & Newnam, Inc. (LAN) and AQUA TERRA Consultants (a division of RESPEC), developed comprehensive hydrodynamic and water quality models using the Hydrological Simulation Program-FORTRAN (HSPF) for several urban watersheds in the San Antonio River Basin. These models enabled watershed management to look at water quality issues on a more refined temporal and spatial scale than the limited monitoring data. They also provided a means to locate and quantify potential water quality impairments and evaluate the effects of mitigation measures. To support the models, a suite of software tools were developed. including: 1) SARA Timeseries Utility Tool for managing and processing of large model timeseries files, 2) SARA Load Reduction Tool to determine load reductions needed to achieve screening levels for each modeled constituent on a sub-basin basis, and 3) SARA Enhanced BMP Tool to determine the optimal combination of BMP types and units needed to achieve the required load reductions. Using these SARA models and tools, water quality agencies and stormwater professionals can determine the optimal combinations of BMP/LID to accomplish their goals and save substantial stormwater infrastructure and management costs. The tools can also help regulators and permittees evaluate the feasibility of achieving compliance

  10. Motivational interviewing: a valuable tool for the psychiatric advanced practice nurse.

    Science.gov (United States)

    Karzenowski, Abby; Puskar, Kathy

    2011-01-01

    Motivational Interviewing (MI) is well known and respected by many health care professionals. Developed by Miller and Rollnick (2002) , it is a way to promote behavior change from within and resolve ambivalence. MI is individualized and is most commonly used in the psychiatric setting; it is a valuable tool for the Psychiatric Advanced Nurse Practice Nurse. There are many resources that talk about what MI is and the principles used to apply it. However, there is little information about how to incorporate MI into a clinical case. This article provides a summary of articles related to MI and discusses two case studies using MI and why advanced practice nurses should use MI with their patients.

  11. Open Innovation Strategy: Open platform-based digital mapping; as tools for value creation and value capture : Case study of OpenStreetMap and Google Maps

    OpenAIRE

    William, Jeffry Leonardo; Wijaya, Mochamad Rifky

    2017-01-01

    Open innovation has been rising in popularity as an alternative to traditional model for organizations to enhance innovation in their products or services. In the past, the innovation processes was time-consuming and costly. It has now become significantly efficient and effective, supported by the advancement of today’s IT such as Internet, Cloud Computing and Big Data. Open innovation has changed the aspect of the innovation source; from closed internal R&D to fully utilization of consum...

  12. NASA Technical Interchange Meeting (TIM): Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box

    Science.gov (United States)

    ONeil, D. A.; Craig, D. A.; Christensen, C. B.; Gresham, E. C.

    2005-01-01

    The objective of this Technical Interchange Meeting was to increase the quantity and quality of technical, cost, and programmatic data used to model the impact of investing in different technologies. The focus of this meeting was the Technology Tool Box (TTB), a database of performance, operations, and programmatic parameters provided by technologists and used by systems engineers. The TTB is the data repository used by a system of models known as the Advanced Technology Lifecycle Analysis System (ATLAS). This report describes the result of the November meeting, and also provides background information on ATLAS and the TTB.

  13. Advanced computational tools and methods for nuclear analyses of fusion technology systems

    International Nuclear Information System (INIS)

    Fischer, U.; Chen, Y.; Pereslavtsev, P.; Simakov, S.P.; Tsige-Tamirat, H.; Loughlin, M.; Perel, R.L.; Petrizzi, L.; Tautges, T.J.; Wilson, P.P.H.

    2005-01-01

    An overview is presented of advanced computational tools and methods developed recently for nuclear analyses of Fusion Technology systems such as the experimental device ITER ('International Thermonuclear Experimental Reactor') and the intense neutron source IFMIF ('International Fusion Material Irradiation Facility'). These include Monte Carlo based computational schemes for the calculation of three-dimensional shut-down dose rate distributions, methods, codes and interfaces for the use of CAD geometry models in Monte Carlo transport calculations, algorithms for Monte Carlo based sensitivity/uncertainty calculations, as well as computational techniques and data for IFMIF neutronics and activation calculations. (author)

  14. Intelligent tools for building a scientific information platform advanced architectures and solutions

    CERN Document Server

    Skonieczny, Lukasz; Rybinski, Henryk; Kryszkiewicz, Marzena; Niezgodka, Marek

    2013-01-01

    This book is a selection of results obtained within two years of research per- formed under SYNAT - a nation-wide scientific project aiming at creating an infrastructure for scientific content storage and sharing for academia, education and open knowledge society in Poland. The selection refers to the research in artificial intelligence, knowledge discovery and data mining, information retrieval and natural language processing, addressing the problems of implementing intelligent tools for building a scientific information platform.This book is a continuation and extension of the ideas presented in “Intelligent Tools for Building a Scientific Information Platform” published as volume 390 in the same series in 2012. It is based on the SYNAT 2012 Workshop held in Warsaw. The papers included in this volume present an overview and insight into information retrieval, repository systems, text processing, ontology-based systems, text mining, multimedia data processing and advanced software engineering.  

  15. Systems Biology-Driven Hypotheses Tested In Vivo: The Need to Advancing Molecular Imaging Tools.

    Science.gov (United States)

    Verma, Garima; Palombo, Alessandro; Grigioni, Mauro; La Monaca, Morena; D'Avenio, Giuseppe

    2018-01-01

    Processing and interpretation of biological images may provide invaluable insights on complex, living systems because images capture the overall dynamics as a "whole." Therefore, "extraction" of key, quantitative morphological parameters could be, at least in principle, helpful in building a reliable systems biology approach in understanding living objects. Molecular imaging tools for system biology models have attained widespread usage in modern experimental laboratories. Here, we provide an overview on advances in the computational technology and different instrumentations focused on molecular image processing and analysis. Quantitative data analysis through various open source software and algorithmic protocols will provide a novel approach for modeling the experimental research program. Besides this, we also highlight the predictable future trends regarding methods for automatically analyzing biological data. Such tools will be very useful to understand the detailed biological and mathematical expressions under in-silico system biology processes with modeling properties.

  16. Synthetic biology and molecular genetics in non-conventional yeasts: Current tools and future advances.

    Science.gov (United States)

    Wagner, James M; Alper, Hal S

    2016-04-01

    Coupling the tools of synthetic biology with traditional molecular genetic techniques can enable the rapid prototyping and optimization of yeast strains. While the era of yeast synthetic biology began in the well-characterized model organism Saccharomyces cerevisiae, it is swiftly expanding to include non-conventional yeast production systems such as Hansenula polymorpha, Kluyveromyces lactis, Pichia pastoris, and Yarrowia lipolytica. These yeasts already have roles in the manufacture of vaccines, therapeutic proteins, food additives, and biorenewable chemicals, but recent synthetic biology advances have the potential to greatly expand and diversify their impact on biotechnology. In this review, we summarize the development of synthetic biological tools (including promoters and terminators) and enabling molecular genetics approaches that have been applied in these four promising alternative biomanufacturing platforms. An emphasis is placed on synthetic parts and genome editing tools. Finally, we discuss examples of synthetic tools developed in other organisms that can be adapted or optimized for these hosts in the near future. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Global search tool for the Advanced Photon Source Integrated Relational Model of Installed Systems (IRMIS) database

    International Nuclear Information System (INIS)

    Quock, D.E.R.; Cianciarulo, M.B.

    2007-01-01

    The Integrated Relational Model of Installed Systems (IRMIS) is a relational database tool that has been implemented at the Advanced Photon Source to maintain an updated account of approximately 600 control system software applications, 400,000 process variables, and 30,000 control system hardware components. To effectively display this large amount of control system information to operators and engineers, IRMIS was initially built with nine Web-based viewers: Applications Organizing Index, IOC, PLC, Component Type, Installed Components, Network, Controls Spares, Process Variables, and Cables. However, since each viewer is designed to provide details from only one major category of the control system, the necessity for a one-stop global search tool for the entire database became apparent. The user requirements for extremely fast database search time and ease of navigation through search results led to the choice of Asynchronous JavaScript and XML (AJAX) technology in the implementation of the IRMIS global search tool. Unique features of the global search tool include a two-tier level of displayed search results, and a database data integrity validation and reporting mechanism.

  18. Development of an innovative uav-mountd screening tool for landfill gas emisiions

    DEFF Research Database (Denmark)

    Fjelsted, L.; Thomasen, T. B.; Valbjørn, I. L.

    2015-01-01

    Identification of landfill gas emission hot spots are potentially a very time consuming process, and the use of an Unmanned Aerial Vehicle (UAV) based screening tool could be an effective investigation strategy. In this study, the potential use of a long-wave thermal infrared camera was investiga......Identification of landfill gas emission hot spots are potentially a very time consuming process, and the use of an Unmanned Aerial Vehicle (UAV) based screening tool could be an effective investigation strategy. In this study, the potential use of a long-wave thermal infrared camera...... was investigated. The correlation between surface soil temperatures and landfill gas emissions was examined in a field study conducted at Hedeland Landfill near Roskilde, Denmark. The surface temperatures were both measured with a soil thermometer and a long-wave infrared camera and compared to detected methane...

  19. A Case Study Optimizing Human Resources in Rwanda's First Dental School: Three Innovative Management Tools.

    Science.gov (United States)

    Hackley, Donna M; Mumena, Chrispinus H; Gatarayiha, Agnes; Cancedda, Corrado; Barrow, Jane R

    2018-06-01

    Harvard School of Dental Medicine, University of Maryland School of Dentistry, and the University of Rwanda (UR) are collaborating to create Rwanda's first School of Dentistry as part of the Human Resources for Health (HRH) Rwanda initiative that aims to strengthen the health care system of Rwanda. The HRH oral health team developed three management tools to measure progress in systems-strengthening efforts: 1) the road map is an operations plan for the entire dental school and facilitates delivery of the curriculum and management of human and material resources; 2) each HRH U.S. faculty member develops a work plan with targeted deliverables for his or her rotation, which is facilitated with biweekly flash reports that measure progress and keep the faculty member focused on his or her specific deliverables; and 3) the redesigned HRH twinning model, changed from twinning of an HRH faculty member with a single Rwandan faculty member to twinning with multiple Rwandan faculty members based on shared academic interests and goals, has improved efficiency, heightened engagement of the UR dental faculty, and increased the impact of HRH U.S. faculty members. These new tools enable the team to measure its progress toward the collaborative's goals and understand the successes and challenges in moving toward the planned targets. The tools have been valuable instruments in fostering discussion around priorities and deployment of resources as well as in developing strong relationships, enabling two-way exchange of knowledge, and promoting sustainability.

  20. The Sylvia Fedoruk Canadian Centre for Nuclear Innovation: advancing knowledge through partnerships

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, N.; Root, J.H., E-mail: neil.alexander@usask.ca, E-mail: john.root@usask.ca [Sylvia Fedoruk Canadian Centre for Nuclear Innovation, Saskatoon, SK (Canada); Chad, K., E-mail: karen.chad@usask.ca [Univ. of Saskatchewan, Saskatoon, SK (Canada); Bereznai, G., E-mail: george.bereznai@uoit.ca [Univ. of Ontario Inst. of Tech., Faculty of Energy Systems and Nuclear Science, Oshawa, ON (Canada); Dalzell, M.T.J., E-mail: matthew.dalzell@usask.ca [Sylvia Fedoruk Canadian Centre for Nuclear Innovation, Saskatoon, SK (Canada)

    2014-07-01

    The vision of the Sylvia Fedoruk Canadian Centre for Nuclear Innovation is to place the Canadian province of Saskatchewan among global leaders in nuclear research, development and training through partnerships with industry and academia for economic and social benefit. Saskatchewan is one of the world's largest producers of uranium and home to pioneering research in nuclear medicine, most notably the development of cobalt-60 teletherapy. The Fedoruk Centre is striving to build on this legacy through the attainment of four strategic goals: (1) building nuclear expertise and capacity through the support to academic programs and research projects in partnership with industry, academic institutions and research organizations in nuclear medicine, materials research, energy and the environment; (2) enhancing innovation in partnership with the research community and industry; (3) engaging communities and increasing understanding of risks, benefits and potential impacts of nuclear technologies; and (4) ensuring the sustainability and accountability of the Centre and its resources. The Fedoruk Centre's mandate includes the stewardship of select nuclear facilities, the first being a 24 MeV cyclotron and nuclear substances laboratory as a resource for the development of novel imaging agents, training and production of radioisotopes for clinical diagnoses. By attracting new research leadership in the nuclear domain, developing networks of expertise, training highly-qualified personnel in nuclear disciplines, stimulating industrial partnerships, and creating conditions for fact-based conversation regarding nuclear issues, the Fedoruk Centre is working to establish a research and innovation capacity to support a vibrant nuclear sector in Saskatchewan. (author)

  1. The Sylvia Fedoruk Canadian Centre for Nuclear Innovation: advancing knowledge through partnerships

    International Nuclear Information System (INIS)

    Alexander, N.; Root, J.H.; Chad, K.; Bereznai, G.; Dalzell, M.T.J.

    2014-01-01

    The vision of the Sylvia Fedoruk Canadian Centre for Nuclear Innovation is to place the Canadian province of Saskatchewan among global leaders in nuclear research, development and training through partnerships with industry and academia for economic and social benefit. Saskatchewan is one of the world's largest producers of uranium and home to pioneering research in nuclear medicine, most notably the development of cobalt-60 teletherapy. The Fedoruk Centre is striving to build on this legacy through the attainment of four strategic goals: (1) building nuclear expertise and capacity through the support to academic programs and research projects in partnership with industry, academic institutions and research organizations in nuclear medicine, materials research, energy and the environment; (2) enhancing innovation in partnership with the research community and industry; (3) engaging communities and increasing understanding of risks, benefits and potential impacts of nuclear technologies; and (4) ensuring the sustainability and accountability of the Centre and its resources. The Fedoruk Centre's mandate includes the stewardship of select nuclear facilities, the first being a 24 MeV cyclotron and nuclear substances laboratory as a resource for the development of novel imaging agents, training and production of radioisotopes for clinical diagnoses. By attracting new research leadership in the nuclear domain, developing networks of expertise, training highly-qualified personnel in nuclear disciplines, stimulating industrial partnerships, and creating conditions for fact-based conversation regarding nuclear issues, the Fedoruk Centre is working to establish a research and innovation capacity to support a vibrant nuclear sector in Saskatchewan. (author)

  2. Advancing Innovation Through Collaboration: Implementation of the NASA Space Life Sciences Strategy

    Science.gov (United States)

    Davis, Jeffrey R.; Richard, Elizabeth E.

    2010-01-01

    On October 18, 2010, the NASA Human Health and Performance center (NHHPC) was opened to enable collaboration among government, academic and industry members. Membership rapidly grew to 90 members (http://nhhpc.nasa.gov ) and members began identifying collaborative projects as detailed in this article. In addition, a first workshop in open collaboration and innovation was conducted on January 19, 2011 by the NHHPC resulting in additional challenges and projects for further development. This first workshop was a result of the SLSD successes in running open innovation challenges over the past two years. In 2008, the NASA Johnson Space Center, Space Life Sciences Directorate (SLSD) began pilot projects in open innovation (crowd sourcing) to determine if these new internet-based platforms could indeed find solutions to difficult technical problems. From 2008 to 2010, the SLSD issued 34 challenges, 14 externally and 20 internally. The 14 external challenges were conducted through three different vendors: InnoCentive, Yet2.com and TopCoder. The 20 internal challenges were conducted using the InnoCentive platform, customized to NASA use, and promoted as NASA@Work. The results from the 34 challenges involved not only technical solutions that were reported previously at the 61st IAC, but also the formation of new collaborative relationships. For example, the TopCoder pilot was expanded by the NASA Space Operations Mission Directorate to the NASA Tournament Lab in collaboration with Harvard Business School and TopCoder. Building on these initial successes, the NHHPC workshop in January of 2011, and ongoing NHHPC member discussions, several important collaborations have been developed: (1) Space Act Agreement between NASA and GE for collaborative projects (2) NASA and academia for a Visual Impairment / Intracranial Hypertension summit (February 2011) (3) NASA and the DoD through the Defense Venture Catalyst Initiative (DeVenCI) for a technical needs workshop (June 2011) (4

  3. Innovative experimental particle physics through technological advances: Past, present and future

    International Nuclear Information System (INIS)

    Cheung, Harry W.K.; Fermilab

    2005-01-01

    This mini-course gives an introduction to the techniques used in experimental particle physics with an emphasis on the impact of technological advances. The basic detector types and particle accelerator facilities will be briefly covered with examples of their use and with comparisons. The mini-course ends with what can be expected in the near future from current technology advances. The mini-course is intended for graduate students and post-docs and as an introduction to experimental techniques for theorists

  4. In Silico PCR Tools for a Fast Primer, Probe, and Advanced Searching.

    Science.gov (United States)

    Kalendar, Ruslan; Muterko, Alexandr; Shamekova, Malika; Zhambakin, Kabyl

    2017-01-01

    The polymerase chain reaction (PCR) is fundamental to molecular biology and is the most important practical molecular technique for the research laboratory. The principle of this technique has been further used and applied in plenty of other simple or complex nucleic acid amplification technologies (NAAT). In parallel to laboratory "wet bench" experiments for nucleic acid amplification technologies, in silico or virtual (bioinformatics) approaches have been developed, among which in silico PCR analysis. In silico NAAT analysis is a useful and efficient complementary method to ensure the specificity of primers or probes for an extensive range of PCR applications from homology gene discovery, molecular diagnosis, DNA fingerprinting, and repeat searching. Predicting sensitivity and specificity of primers and probes requires a search to determine whether they match a database with an optimal number of mismatches, similarity, and stability. In the development of in silico bioinformatics tools for nucleic acid amplification technologies, the prospects for the development of new NAAT or similar approaches should be taken into account, including forward-looking and comprehensive analysis that is not limited to only one PCR technique variant. The software FastPCR and the online Java web tool are integrated tools for in silico PCR of linear and circular DNA, multiple primer or probe searches in large or small databases and for advanced search. These tools are suitable for processing of batch files that are essential for automation when working with large amounts of data. The FastPCR software is available for download at http://primerdigital.com/fastpcr.html and the online Java version at http://primerdigital.com/tools/pcr.html .

  5. Overview of experimental work to ensure innovation of nuclear fuel for future advanced PWRs

    International Nuclear Information System (INIS)

    Zymak, J.; Valach, M.; Hejna, J.

    2002-11-01

    It is envisaged that advanced nuclear fuel will be operated in high burnup conditions, at a high linear power and at considerable mechanical fuel-cladding interactions. The report gives an overview of experimental work investigating phenomena that will affect APWR fuel, such as the manufacturing technology, thermal properties and safety requirements

  6. Ethnodrama: An Innovative Knowledge Translation Tool in the Management of Lymphedema.

    Science.gov (United States)

    Ahmed, Shahid; Quinlan, Elizabeth; McMullen, Linda; Thomas, Roanne; Fichtner, Pam; Block, Janice

    2015-01-01

    Lymphedema can cause significant physical impairment and quality-of-life issues. Yet there is a gap in knowledge about lymphedema among breast cancer survivors (BCS), and health care professionals (HCP). Ethnodrama is an innovative knowledge translation strategy that uses theatrical performances for dissemination of research results. We evaluated the impact of live ethnodrama on HCP' and BCS' awareness and attitudes in relation to impact of lymphedema on BCS' lives. Ethnodrama performances were developed by script writers and a theatre director in collaboration with the investigators and BCS using data from published research and pre-performances workshops. Six interactive live performances were given to audiences of BCS, HCP, and community members in four cities across Canada. After watching these live performances, members of the audiences were asked to complete a paper-based questionnaire regarding their knowledge of lymphedema, and their attitudes and practices toward lymphedema. Of 238 audience members who participated in the survey, 55 (23%) were BCS and 85 (37.5%) were HCP. Most members rated the performances as very effective in changing their (84%) or other people's (93%) understanding of lymphedema; 96% reported being motivated to seek additional information on lymphedema, and 72% of HCP anticipated changes in their practices related to lymphedema screening. Overall no significant differences were noted in responses to ethnodrama between BCS and HCP. Open-ended responses were supportive of the findings from the closed-ended questions. Our results indicate that ethnodrama performances effectively convey information and positively affecting changes in HCP' and BCS' attitudes toward lymphedema.

  7. An Innovative Interactive Modeling Tool to Analyze Scenario-Based Physician Workforce Supply and Demand

    Science.gov (United States)

    Gupta, Saurabh; Black-Schaffer, W. Stephen; Crawford, James M.; Gross, David; Karcher, Donald S.; Kaufman, Jill; Knapman, Doug; Prystowsky, Michael B.; Wheeler, Thomas M.; Bean, Sarah; Kumar, Paramhans; Sharma, Raghav; Chamoli, Vaibhav; Ghai, Vikrant; Gogia, Vineet; Weintraub, Sally; Cohen, Michael B.

    2015-01-01

    Effective physician workforce management requires that the various organizations comprising the House of Medicine be able to assess their current and future workforce supply. This information has direct relevance to funding of graduate medical education. We describe a dynamic modeling tool that examines how individual factors and practice variables can be used to measure and forecast the supply and demand for existing and new physician services. The system we describe, while built to analyze the pathologist workforce, is sufficiently broad and robust for use in any medical specialty. Our design provides a computer-based software model populated with data from surveys and best estimates by specialty experts about current and new activities in the scope of practice. The model describes the steps needed and data required for analysis of supply and demand. Our modeling tool allows educators and policy makers, in addition to physician specialty organizations, to assess how various factors may affect demand (and supply) of current and emerging services. Examples of factors evaluated include types of professional services (3 categories with 16 subcategories), service locations, elements related to the Patient Protection and Affordable Care Act, new technologies, aging population, and changing roles in capitated, value-based, and team-based systems of care. The model also helps identify where physicians in a given specialty will likely need to assume new roles, develop new expertise, and become more efficient in practice to accommodate new value-based payment models. PMID:28725751

  8. An Innovative Interactive Modeling Tool to Analyze Scenario-Based Physician Workforce Supply and Demand

    Directory of Open Access Journals (Sweden)

    Saurabh Gupta BPharm

    2015-10-01

    Full Text Available Effective physician workforce management requires that the various organizations comprising the House of Medicine be able to assess their current and future workforce supply. This information has direct relevance to funding of graduate medical education. We describe a dynamic modeling tool that examines how individual factors and practice variables can be used to measure and forecast the supply and demand for existing and new physician services. The system we describe, while built to analyze the pathologist workforce, is sufficiently broad and robust for use in any medical specialty. Our design provides a computer-based software model populated with data from surveys and best estimates by specialty experts about current and new activities in the scope of practice. The model describes the steps needed and data required for analysis of supply and demand. Our modeling tool allows educators and policy makers, in addition to physician specialty organizations, to assess how various factors may affect demand (and supply of current and emerging services. Examples of factors evaluated include types of professional services (3 categories with 16 subcategories, service locations, elements related to the Patient Protection and Affordable Care Act, new technologies, aging population, and changing roles in capitated, value-based, and team-based systems of care. The model also helps identify where physicians in a given specialty will likely need to assume new roles, develop new expertise, and become more efficient in practice to accommodate new value-based payment models.

  9. An Innovative Interactive Modeling Tool to Analyze Scenario-Based Physician Workforce Supply and Demand.

    Science.gov (United States)

    Gupta, Saurabh; Black-Schaffer, W Stephen; Crawford, James M; Gross, David; Karcher, Donald S; Kaufman, Jill; Knapman, Doug; Prystowsky, Michael B; Wheeler, Thomas M; Bean, Sarah; Kumar, Paramhans; Sharma, Raghav; Chamoli, Vaibhav; Ghai, Vikrant; Gogia, Vineet; Weintraub, Sally; Cohen, Michael B; Robboy, Stanley J

    2015-01-01

    Effective physician workforce management requires that the various organizations comprising the House of Medicine be able to assess their current and future workforce supply. This information has direct relevance to funding of graduate medical education. We describe a dynamic modeling tool that examines how individual factors and practice variables can be used to measure and forecast the supply and demand for existing and new physician services. The system we describe, while built to analyze the pathologist workforce, is sufficiently broad and robust for use in any medical specialty. Our design provides a computer-based software model populated with data from surveys and best estimates by specialty experts about current and new activities in the scope of practice. The model describes the steps needed and data required for analysis of supply and demand. Our modeling tool allows educators and policy makers, in addition to physician specialty organizations, to assess how various factors may affect demand (and supply) of current and emerging services. Examples of factors evaluated include types of professional services (3 categories with 16 subcategories), service locations, elements related to the Patient Protection and Affordable Care Act, new technologies, aging population, and changing roles in capitated, value-based, and team-based systems of care. The model also helps identify where physicians in a given specialty will likely need to assume new roles, develop new expertise, and become more efficient in practice to accommodate new value-based payment models.

  10. Science in the Eyes of Preschool Children: Findings from an Innovative Research Tool

    Science.gov (United States)

    Dubosarsky, Mia D.

    How do young children view science? Do these views reflect cultural stereotypes? When do these views develop? These fundamental questions in the field of science education have rarely been studied with the population of preschool children. One main reason is the lack of an appropriate research instrument that addresses preschool children's developmental competencies. Extensive body of research has pointed at the significance of early childhood experiences in developing positive attitudes and interests toward learning in general and the learning of science in particular. Theoretical and empirical research suggests that stereotypical views of science may be replaced by authentic views following inquiry science experience. However, no preschool science intervention program could be designed without a reliable instrument that provides baseline information about preschool children's current views of science. The current study presents preschool children's views of science as gathered from a pioneering research tool. This tool, in the form of a computer "game," does not require reading, writing, or expressive language skills and is operated by the children. The program engages children in several simple tasks involving picture recognition and yes/no answers in order to reveal their views about science. The study was conducted with 120 preschool children in two phases and found that by the age of 4 years, participants possess an emergent concept of science. Gender and school differences were detected. Findings from this interdisciplinary study will contribute to the fields of early childhood, science education, learning technologies, program evaluation, and early childhood curriculum development.

  11. Innovative fabrication processing of advanced composite materials concepts for primary aircraft structures

    Science.gov (United States)

    Kassapoglou, Christos; Dinicola, Al J.; Chou, Jack C.

    1992-01-01

    The autoclave based THERM-X(sub R) process was evaluated by cocuring complex curved panels with frames and stiffeners. The process was shown to result in composite parts of high quality with good compaction at sharp radius regions and corners of intersecting parts. The structural properties of the postbuckled panels fabricated were found to be equivalent to those of conventionally tooled hand laid-up parts. Significant savings in bagging time over conventional tooling were documented. Structural details such as cocured shear ties and embedded stiffener flanges in the skin were found to suppress failure modes such as failure at corners of intersecting members and skin stiffeners separation.

  12. Launching the dialogue: Safety and innovation as partners for success in advanced manufacturing.

    Science.gov (United States)

    Geraci, C L; Tinkle, S S; Brenner, S A; Hodson, L L; Pomeroy-Carter, C A; Neu-Baker, N

    2018-06-01

    Emerging and novel technologies, materials, and information integrated into increasingly automated and networked manufacturing processes or into traditional manufacturing settings are enhancing the efficiency and productivity of manufacturing. Globally, there is a move toward a new era in manufacturing that is characterized by: (1) the ability to create and deliver more complex designs of products; (2) the creation and use of materials with new properties that meet a design need; (3) the employment of new technologies, such as additive and digital techniques that improve on conventional manufacturing processes; and (4) a compression of the time from initial design concept to the creation of a final product. Globally, this movement has many names, but "advanced manufacturing" has become the shorthand for this complex integration of material and technology elements that enable new ways to manufacture existing products, as well as new products emerging from new technologies and new design methods. As the breadth of activities associated with advanced manufacturing suggests, there is no single advanced manufacturing industry. Instead, aspects of advanced manufacturing can be identified across a diverse set of business sectors that use manufacturing technologies, ranging from the semiconductors and electronics to the automotive and pharmaceutical industries. The breadth and diversity of advanced manufacturing may change the occupational and environmental risk profile, challenge the basic elements of comprehensive health and safety (material, process, worker, environment, product, and general public health and safety), and provide an opportunity for development and dissemination of occupational and environmental health and safety (OEHS) guidance and best practices. It is unknown how much the risk profile of different elements of OEHS will change, thus requiring an evolution of health and safety practices. These changes may be accomplished most effectively through multi

  13. Music Therapy Advances in Neuro-disability - Innovations in Research and Practice

    DEFF Research Database (Denmark)

    O'Kelly, Julian; Magee, Wendy L.; Street, Alex

    2014-01-01

    therapy, music neuroscience and music psychology addressing the needs of those with acquired and degenerative neurological conditions. The diverse and evolving work in this field is reflected in the topics covered, including disorders of consciousness, dementia, stroke, and the use of modern neuro......-imaging methods to measure the effects of music therapy at a cortical level. A discussion of the implications of these converging foci highlights the benefits of the cross-disciplinary dialogue that characterised the conference.......This article provides a summary of the oral papers presented during a two day international conference, which took place on 7th & 8th June 2013, at the Royal Hospital for Neuro-disability (RHN) in London. The summary texts detail innovative research projects and clinical developments across music...

  14. Coevolution of patients and hospitals: how changing epidemiology and technological advances create challenges and drive organizational innovation.

    Science.gov (United States)

    Lega, Federico; Calciolari, Stefano

    2012-01-01

    Over the last 20 years, hospitals have revised their organizational structures in response to new environmental pressures. Today, demographic and epidemiologic trends and recent technological advances call for new strategies to cope with ultra-elderly frail patients characterized by chronic conditions, high-severity health problems, and complex social situations. The main areas of change surround new ways of managing emerging clusters of patients whose needs are not efficiently or effectively met within traditional hospital organizations. Following the practitioner and academic literature, we first identify the most relevant clusters of new kinds of patients who represent an increasingly larger share of the hospital population in developed countries. Second, we propose a framework that synthesizes the major organizational innovations adopted by successful organizations around the world. We conclude by substantiating the trends of and the reasoning behind the prospective pattern of hospital organizational development.

  15. Contemporary molecular tools in microbial ecology and their application to advancing biotechnology.

    Science.gov (United States)

    Rashid, Mamoon; Stingl, Ulrich

    2015-12-01

    Novel methods in microbial ecology are revolutionizing our understanding of the structure and function of microbes in the environment, but concomitant advances in applications of these tools to biotechnology are mostly lagging behind. After more than a century of efforts to improve microbial culturing techniques, about 70-80% of microbial diversity - recently called the "microbial dark matter" - remains uncultured. In early attempts to identify and sample these so far uncultured taxonomic lineages, methods that amplify and sequence ribosomal RNA genes were extensively used. Recent developments in cell separation techniques, DNA amplification, and high-throughput DNA sequencing platforms have now made the discovery of genes/genomes of uncultured microorganisms from different environments possible through the use of metagenomic techniques and single-cell genomics. When used synergistically, these metagenomic and single-cell techniques create a powerful tool to study microbial diversity. These genomics techniques have already been successfully exploited to identify sources for i) novel enzymes or natural products for biotechnology applications, ii) novel genes from extremophiles, and iii) whole genomes or operons from uncultured microbes. More can be done to utilize these tools more efficiently in biotechnology. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Contemporary molecular tools in microbial ecology and their application to advancing biotechnology

    KAUST Repository

    Rashid, Mamoon; Stingl, Ulrich

    2015-01-01

    Novel methods in microbial ecology are revolutionizing our understanding of the structure and function of microbes in the environment, but concomitant advances in applications of these tools to biotechnology are mostly lagging behind. After more than a century of efforts to improve microbial culturing techniques, about 70–80% of microbial diversity – recently called the “microbial dark matter” – remains uncultured. In early attempts to identify and sample these so far uncultured taxonomic lineages, methods that amplify and sequence ribosomal RNA genes were extensively used. Recent developments in cell separation techniques, DNA amplification, and high-throughput DNA sequencing platforms have now made the discovery of genes/genomes of uncultured microorganisms from different environments possible through the use of metagenomic techniques and single-cell genomics. When used synergistically, these metagenomic and single-cell techniques create a powerful tool to study microbial diversity. These genomics techniques have already been successfully exploited to identify sources for i) novel enzymes or natural products for biotechnology applications, ii) novel genes from extremophiles, and iii) whole genomes or operons from uncultured microbes. More can be done to utilize these tools more efficiently in biotechnology.

  17. Contemporary molecular tools in microbial ecology and their application to advancing biotechnology

    KAUST Repository

    Rashid, Mamoon

    2015-09-25

    Novel methods in microbial ecology are revolutionizing our understanding of the structure and function of microbes in the environment, but concomitant advances in applications of these tools to biotechnology are mostly lagging behind. After more than a century of efforts to improve microbial culturing techniques, about 70–80% of microbial diversity – recently called the “microbial dark matter” – remains uncultured. In early attempts to identify and sample these so far uncultured taxonomic lineages, methods that amplify and sequence ribosomal RNA genes were extensively used. Recent developments in cell separation techniques, DNA amplification, and high-throughput DNA sequencing platforms have now made the discovery of genes/genomes of uncultured microorganisms from different environments possible through the use of metagenomic techniques and single-cell genomics. When used synergistically, these metagenomic and single-cell techniques create a powerful tool to study microbial diversity. These genomics techniques have already been successfully exploited to identify sources for i) novel enzymes or natural products for biotechnology applications, ii) novel genes from extremophiles, and iii) whole genomes or operons from uncultured microbes. More can be done to utilize these tools more efficiently in biotechnology.

  18. Synergy between scientific advancement and technological innovation, illustrated by a mechanism-based model characterizing sodium-glucose cotransporter-2 inhibition.

    Science.gov (United States)

    Zhang, Liping; Ng, Chee M; List, James F; Pfister, Marc

    2010-09-01

    Advances in experimental medicine and technological innovation during the past century have brought tremendous progress in modern medicine and generated an ever-increasing amount of data from bench and bedside. The desire to extend scientific knowledge motivates effective data integration. Technological innovation makes this possible, which in turn accelerates the advancement in science. This mutually beneficial interaction is illustrated by the development of an expanded mechanism-based model for understanding a novel mechanism, sodium-glucose cotransporter-2 SGLT2 inhibition for potential treatment of type 2 diabetes mellitus.

  19. Advanced technology care innovation for older people in Italy: necessity and opportunity to promote health and wellbeing.

    Science.gov (United States)

    Lattanzio, Fabrizia; Abbatecola, Angela M; Bevilacqua, Roberta; Chiatti, Carlos; Corsonello, Andrea; Rossi, Lorena; Bustacchini, Silvia; Bernabei, Roberto

    2014-07-01

    Even though there is a constant and accelerating growth of the aging population worldwide, such a rapid rise is negatively impacting available home and community services not able to encompass the necessities associated with the increased number of older people. In particular, there are increasing demands on e-health care services and smart technologies needed for frail elders with chronic diseases and also for those experiencing active aging. Advanced Technology Care Innovation for older persons encompasses all sectors (assistive technology, robotics, home automation, and home care- and institution-based healthcare monitoring, telemedicine) dedicated to promoting health and wellbeing in all types of living environments. Considering that there is a large concern and demand by older persons to remain in familiar social living surroundings, study projects joined with industries have been currently initiated, especially across Europe to improve health and wellbeing. This article will highlight the latest updates in Europe and, in particular in Italy, regarding scientific projects dedicated to unraveling how diverse needs can be translated into an up-to-date technology innovation for the growing elder population. We will provide information regarding advanced technology designed for those with specific geriatric-correlated conditions in familiar living settings and for individuals aging actively. This is an important action because numerous emerging developments are based on user needs identified by geriatricians, thus, underlining the indispensable role of geriatric medicine toward future guidelines on specific technology. Copyright © 2014 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

  20. Millimeter-wave imaging of magnetic fusion plasmas: technology innovations advancing physics understanding

    Science.gov (United States)

    Wang, Y.; Tobias, B.; Chang, Y.-T.; Yu, J.-H.; Li, M.; Hu, F.; Chen, M.; Mamidanna, M.; Phan, T.; Pham, A.-V.; Gu, J.; Liu, X.; Zhu, Y.; Domier, C. W.; Shi, L.; Valeo, E.; Kramer, G. J.; Kuwahara, D.; Nagayama, Y.; Mase, A.; Luhmann, N. C., Jr.

    2017-07-01

    Electron cyclotron emission (ECE) imaging is a passive radiometric technique that measures electron temperature fluctuations; and microwave imaging reflectometry (MIR) is an active radar imaging technique that measures electron density fluctuations. Microwave imaging diagnostic instruments employing these techniques have made important contributions to fusion science and have been adopted at major fusion facilities worldwide including DIII-D, EAST, ASDEX Upgrade, HL-2A, KSTAR, LHD, and J-TEXT. In this paper, we describe the development status of three major technological advancements: custom mm-wave integrated circuits (ICs), digital beamforming (DBF), and synthetic diagnostic modeling (SDM). These have the potential to greatly advance microwave fusion plasma imaging, enabling compact and low-noise transceiver systems with real-time, fast tracking ability to address critical fusion physics issues, including ELM suppression and disruptions in the ITER baseline scenario, naturally ELM-free states such as QH-mode, and energetic particle confinement (i.e. Alfvén eigenmode stability) in high-performance regimes that include steady-state and advanced tokamak scenarios. Furthermore, these systems are fully compatible with today’s most challenging non-inductive heating and current drive systems and capable of operating in harsh environments, making them the ideal approach for diagnosing long-pulse and steady-state tokamaks.

  1. Innovation in the planning of V-Y rotation advancement flaps: A template for flap design

    Directory of Open Access Journals (Sweden)

    Utku Can Dölen

    2018-01-01

    Full Text Available Local flaps exhibit excellent color matching that no other type of flap can compete with. Moreover, surgery using a local flap is easier and faster than surgery using a distant or free flap. However, local flaps can be much more difficult to design. We designed 2 templates to plan a V-Y rotation advancement flap. The template for a unilateral V-Y rotation advancement flap was used on the face (n=5, anterior tibia (n=1, posterior axilla (n=1, ischium (n=1, and trochanter (n=2. The template for a bilateral flap was used on the sacrum (n=8, arm (n=1, and anterior tibia (n=1. The causes of the defects were meningocele (n=3, a decubitus ulcer (n=5, pilonidal sinus (n=3, and skin tumor excision (n=10. The meningocele patients were younger than 8 days. The mean age of the adult patients was 50.4 years (range, 19–80 years. All the donor areas of the flaps were closed primarily. None of the patients experienced wound dehiscence or partial/total flap necrosis. The templates guided surgeons regarding the length and the placement of the incision for a V-Y rotation advancement flap according to the size of the wound. In addition, they could be used for the training of residents.

  2. The emergence of forensic nursing and advanced nursing practice in Switzerland: an innovative case study consultation.

    Science.gov (United States)

    Romain-Glassey, Nathalie; Ninane, Françoise; de Puy, Jacqueline; Abt, Maryline; Mangin, Patrice; Morin, Diane

    2014-01-01

    The objectives of this article were to systematically describe and examine the novel roles and responsibilities assumed by nurses in a forensic consultation for victims of violence at a University Hospital in French-speaking Switzerland. Utilizing a case study methodology, information was collected from two main sources: (a) discussion groups with nurses and forensic pathologists and (b) a review of procedures and protocols. Following a critical content analysis, the roles and responsibilities of the forensic nurses were described and compared with the seven core competencies of advanced nursing practice as outlined by Hamric, Spross, and Hanson (2009). Advanced nursing practice competencies noted in the analysis included "direct clinical practice," "coaching and guidance," and "collaboration." The role of the nurse in terms of "consultation," "leadership," "ethics," and "research" was less evident in the analysis. New forms of nursing are indeed practiced in the forensic clinical setting, and our findings suggest that nursing practice in this domain is following the footprints of an advanced nursing practice model. Further reflections are required to determine whether the role of the forensic nurse in Switzerland should be developed as a clinical nurse specialist or that of a nurse practitioner.

  3. Damage Characterization and Real-Time Health Monitoring of Aerospace Materials Using Innovative NDE Tools

    Science.gov (United States)

    Matikas, Theodore E.

    2010-07-01

    The objective of this work is to characterize the damage and monitor in real-time aging structural components used in aerospace applications by means of advanced nondestructive evaluation techniques. Two novel experimental methodologies are used in this study, based on ultrasonic microscopy and nonlinear acoustics. It is demonstrated in this work that ultrasonic microscopy can be successfully utilized for local elastic property measurement, crack-size determination as well as for interfacial damage evaluation in high-temperature materials, such as metal matrix composites. Nonlinear acoustics enables real-time monitoring of material degradation in aerospace structures. When a sinusoidal ultrasonic wave of a given frequency and of sufficient amplitude is introduced into a nonharmonic solid, the fundamental wave distorts as it propagates, and therefore the second and higher harmonics of the fundamental frequency are generated. Measurements of the amplitude of these harmonics provide information on the coefficient of second- and higher-order terms of the stress-strain relation for a nonlinear solid. It is shown in this article that the material bulk nonlinear parameter for metallic alloy samples at different fatigue levels exhibits large changes compared to linear ultrasonic parameters, such as velocity and attenuation.

  4. Index of Access: a new innovative and dynamic tool for rural health service and workforce planning.

    Science.gov (United States)

    McGrail, Matthew R; Russell, Deborah J; Humphreys, John S

    2017-10-01

    Objective Improving access to primary health care (PHC) remains a key issue for rural residents and health service planners. This study aims to show that how access to PHC services is measured has important implications for rural health service and workforce planning. Methods A more sophisticated tool to measure access to PHC services is proposed, which can help health service planners overcome the shortcomings of existing measures and long-standing access barriers to PHC. Critically, the proposed Index of Access captures key components of access and uses a floating catchment approach to better define service areas and population accessibility levels. Moreover, as demonstrated through a case study, the Index of Access enables modelling of the effects of workforce supply variations. Results Hypothetical increases in supply are modelled for a range of regional centres, medium and small rural towns, with resulting changes of access scores valuable to informing health service and workforce planning decisions. Conclusions The availability and application of a specific 'fit-for-purpose' access measure enables a more accurate empirical basis for service planning and allocation of health resources. This measure has great potential for improved identification of PHC access inequities and guiding redistribution of PHC services to correct such inequities. What is known about the topic? Resource allocation and health service planning decisions for rural and remote health settings are currently based on either simple measures of access (e.g. provider-to-population ratios) or proxy measures of access (e.g. standard geographical classifications). Both approaches have substantial limitations for informing rural health service planning and decision making. What does this paper add? The adoption of a new improved tool to measure access to PHC services, the Index of Access, is proposed to assist health service and workforce planning. Its usefulness for health service planning is

  5. Development of innovative inspection tools for higher reliability of PHWR fuel

    International Nuclear Information System (INIS)

    Kamalesh Kumar, B.; Viswanathan, B.; Laxminarayana, B.; Ganguly, C.

    2003-01-01

    'Full text:' Advent of Computer aided manufacturing systems has led to very high rate of production with greater reliability. The conventional inspection tools and systems, which are often manual based do not complement with output of highly automated production line. In order to overcome the deficiency, a strategic plan was developed for having automated inspection facility for PHWR fuel assembly line. Laser based systems with their inherently high accuracy and quick response times are a favorite for metrology purpose. Non-contact nature of laser-based measurement ensures minimal contamination, low wear and tear and good repeatability. So far two laser-based systems viz. Pellet density measurement systems and triangulation sensors have been developed. Laser based fuel pellet inspection system and PHWR fuel bundle metric station are under development. Machine vision-based systems have been developed to overcome certain limitations when inspection has to be carried out on such a large scale manually. These deficiencies arise from limitations of resolution, accessibility, fatigue and absence of quantification ability. These problems get further compounded in inspection of fuel components because of their relatively small sizes, close tolerances required and the reflective surfaces. PC based vision system has been developed for inspecting components and fuel assemblies. The paper would touch upon the details of the various laser systems and vision systems that have been indigenously developed for PHWR Fuel Metrology and their impact on the assembly production line. (author)

  6. Student perceptions and effectiveness of an innovative learning tool: Anatomy Glove Learning System.

    Science.gov (United States)

    Lisk, Kristina; McKee, Pat; Baskwill, Amanda; Agur, Anne M R

    2015-01-01

    A trend in anatomical education is the development of alternative pedagogical approaches to replace or complement experiences in a cadaver laboratory; however, empirical evidence on their effectiveness is often not reported. This study aimed to evaluate the effectiveness of Anatomy Glove Learning System (AGLS), which enables students to learn the relationship between hand structure and function by drawing the structures onto a worn glove with imprinted bones. Massage therapy students (n = 73) were allocated into two groups and drew muscles onto either: (1) the glove using AGLS instructional videos (3D group); or (2) paper with palmar/dorsal views of hand bones during an instructor-guided activity (2D group). A self-confidence measure and knowledge test were completed before, immediately after, and one-week following the learning conditions. Self-confidence of hand anatomy in the 3D group gradually increased (3.2/10, 4.7/10, and 4.8/10), whereas self-confidence in the 2D group began to decline one-week later (3.2/10, 4.4/10, and 3.9/10). Knowledge of hand anatomy improved in both groups immediately after learning, (P learning tool (mean = 8.6 ± 2.2). This study provides evidence demonstrating that AGLS and the traditional 2D learning approach are equally effective in promoting students' self-confidence and knowledge of hand anatomy. © 2014 American Association of Anatomists.

  7. Case-based debates: an innovative teaching tool in nephrology education.

    Science.gov (United States)

    Jhaveri, Kenar D; Chawla, Arun; Shah, Hitesh H

    2012-01-01

    Medical educators have called for new teaching methods and materials that supplement the traditional lecture format, and education in a range of health professions, including medicine, nursing, and pharmacy, is using a game-based approach to teach learners. Here, we describe a novel teaching tool in a case-based debate using the game format. Two teams of first- and second-year nephrology fellows participated in a PowerPoint game-based debate about which tests to order to diagnose transplant-related case. Our pilot study assessed the participant acceptance of case-based debate sessions and rewards system, and participant perceptions of using this approach to teach fellows and residents the importance of each test ordered and its cost-effectiveness in medicine. Each test ordered requires an explanation and has a point value attached to it (based on relevance and cost of positive and negative test results). The team that comes up with the diagnosis with most points wins the game. A faculty member leads a short concluding discussion. Subjective evaluations found these case-based debates to be highly entertaining and thought-provoking and to enhance self-directed learning.

  8. 1950-nm diode laser-assisted microanastomoses (LAMA): an innovative surgical tool for hand surgery emergencies.

    Science.gov (United States)

    Leclère, Franck Marie; Schoofs, Michel; Vogt, Peter; Casoli, Vincent; Mordon, Serge

    2015-05-01

    Based on previous observations, the 1950-nm diode laser seems to be an ideal wavelength for laser microvascular anastomoses. The data presented here, part of a larger ongoing study, assess its use in emergency hand surgery. Between 2011 and 2014, 11 patients were operated on for hand trauma with laser-assisted microanastomoses (LAMA) and prospectively analysed. LAMA was performed with a 1950-nm diode laser after placement of equidistant stitches. For vessel size laser parameters were used: spot size 400 μm, five spots for each wall, power 125 mW, and arterial/venous fluence 100/90 J/cm(2) (spot duration 1/0.9 s). Mean operating time for arterial and venous microanastomoses was 7.3 ± 1.4 and 8.7 ± 1.0 min, respectively. Three anastomoses required a secondary laser application. Arterial and venous patency rates were 100 % at the time of surgery. The success rate for the 11 procedures assessed clinically and with the Doppler was 100 %. The technique is compared to the current literature. The 1950-nm LAMA is a reliable tool with excellent results in emergency hand surgery. The system is very compact and transportable for utilization in the emergency operating room.

  9. Digital stethoscope as an innovative tool on the teaching of auscultatory skills.

    Science.gov (United States)

    Mesquita, Claudio Tinoco; Reis, Jader Costa dos; Simões, Luciana Silveira; Moura, Eduardo Cardoso de; Rodrigues, Gustavo Amarante; Athayde, Carolina Cunto de; Machado, Hugo Lima; Lanzieri, Pedro Gemal

    2013-02-01

    Physical cardiovascular examination, particularly cardiac auscultation, is one of the most difficult clinical skills for students during their medical training. Studies suggest that the use of technologies such as digital stethoscope increase the accuracy of clinical examination, however, its impact on the teaching of cardiac auscultation for undergraduate students of medicine is not known. The objective is to demonstrate the usefulness of the digital stethoscope compared to traditional methods as a tool in the teaching of auscultatory skills. nterventional, longitudinal, controlled, unicenter and randomized study. Thirty-eight medicine students were enrolled for a cardiovascular semiology course lasting eight weeks. The course program included lectures and bedside practice in Cardiology wards. In the practical lessons, the students were randomized into two groups: 1) (n = 21) digital stethoscope (Littmann® Model 3200, 3M); and 2) (n = 17) conventional stethoscopes. A pre-training evaluation was conducted through a test using the software Heart Sounds®, which was repeated after the course. The average scores were compared by paired T test and unpaired T test. It is observed that, at the end of the course, there was a significantly greater improvement in the group that used the digital stethoscope (51.9%) compared to the group using the conventional stethoscope (29.5%). Short-term interventions for cardiac semiology teaching are able to contribute significantly to improving proficiency in the identification of heart sounds. The use of digital stethoscope proved to be a positive factor in teaching these skills.

  10. OccIDEAS: An Innovative Tool to Assess Past Asbestos Exposure in the Australian Mesothelioma Registry

    Directory of Open Access Journals (Sweden)

    Ewan MacFarlane

    2012-03-01

    Full Text Available Malignant mesothelioma is an uncommon but rapidly fatal disease for which the principal aetiological agent is exposure to asbestos. Mesothelioma is of particular significance in Australia where asbestos use was very widespread from the 1950s until the 1980s. Exposure to asbestos includes occupational exposure associated with working with asbestos or in workplaces where asbestos is used and also ‘take-home’ exposure of family members of asbestos exposed workers. Asbestos exposure may also be nonoccupational, occurring as a consequence of using asbestos products in non-occupational contexts and passive exposure is also possible, such as exposure to asbestos products in the built environment or proximity to an environmental source of exposure, for example an asbestos production plant. The extremely long latency period for this disease makes exposure assessment problematic in the context of a mesothelioma registry. OccIDEAS, a recently developed online tool for retrospective exposure assessment, has been adapted for use in the Australian Mesothelioma Registry (AMR to enable systematic retrospective exposure assessment of consenting cases. Twelve occupational questionnaire modules and one non-occupational module have been developed for the AMR, which form the basis of structured interviews using OccIDEAS, which also stores collected data and provides a framework for generating metrics of exposure.

  11. Advanced core physics and thermal hydraulics analysis of boiling water reactors using innovative fuel concepts

    International Nuclear Information System (INIS)

    Winter, Dominik

    2014-01-01

    The economical operation of a boiling water reactor (BWR) is mainly achieved by the axially uniform utilization of the nuclear fuel in the assemblies which is challenging because the neutron spectrum in the active reactor core varies with the axial position. More precisely, the neutron spectrum becomes harder the higher the position is resulting in a decrease of the fuel utilization because the microscopic fission cross section is smaller by several orders of magnitude. In this work, the use of two fuel concepts based on a mixed oxide (MOX) fuel and an innovative thorium-plutonium (ThPu) fuel is investigated by a developed simulation model encompassing thermal hydraulics, neutronics, and fuel burnup. The main feature of these fuel concepts is the axially varying enrichment in plutonium which is, in this work, recycled from spent nuclear fuel and shows a high fission fraction of the absorption cross section for fast incident neutron energies. The potential of balancing the overall fuel utilization by an increase of the fission rate in the upper part of the active height with a combination of the harder spectrum and the higher fission fraction of the absorption cross section in the BWR core is studied. The three particular calculational models for thermal hydraulics, neutronics, and fuel burnup provide results at fuel assembly and/or at core level. In the former case, the main focus lies on the thermal hydraulics analysis, fuel burnup, and activity evolution after unloading from the core and, in the latter case, special attention is paid to reactivity safety coefficients (feedback effects) and the optimization of the operational behavior. At both levels (assembly and core), the isotopic buildup and depletion rates as a function of the active height are analyzed. In addition, a comparison between the use of conventional fuel types with homogeneous enrichments and the use of the innovative fuel types is made. In the framework of the simulations, the ThPu and the MOX

  12. Innovative Graduate Research Education for Advancement of Implementation Science in Adolescent Behavioral Health.

    Science.gov (United States)

    Burton, Donna L; Levin, Bruce Lubotsky; Massey, Tom; Baldwin, Julie; Williamson, Heather

    2016-04-01

    An innovative approach to research education that integrates the theory and principles of implementation science, participatory research, and service learning in the area of adolescent behavioral health is presented. Qualitative interviews and surveys of program participants have been conducted to assess the program's curricula, service-learning partnerships, student (scholar) satisfaction, and views of community partnerships and academic mentors. The Institute has experienced the successful completion of its first and second cohorts and enrollment of a third cohort of scholars. Community partners are utilizing results of service-learning projects to influence agency operations. Institute scholars have identified research and service learning experiences as key factors in the decision to apply to the Institute graduate certificate program. The availability of tuition support is identified as valuable but not ranked as the most important reason for scholar interest in the program. Academic mentors report positive relationships with community agencies. Future iterations of the program will expand options for distance learning and alternatives to traditional graduate education for community-based scholars. Community partner agency capacity for participation is expected to change over time. Methods are being identified to both sustain existing partnerships and develop new community partnership relationships.

  13. Towards an advanced e-Infrastructure for Civil Protection applications: Research Strategies and Innovation Guidelines

    Science.gov (United States)

    Mazzetti, P.; Nativi, S.; Verlato, M.; Angelini, V.

    2009-04-01

    In the context of the EU co-funded project CYCLOPS (http://www.cyclops-project.eu) the problem of designing an advanced e-Infrastructure for Civil Protection (CP) applications has been addressed. As a preliminary step, some studies about European CP systems and operational applications were performed in order to define their specific system requirements. At a higher level it was verified that CP applications are usually conceived to map CP Business Processes involving different levels of processing including data access, data processing, and output visualization. At their core they usually run one or more Earth Science models for information extraction. The traditional approach based on the development of monolithic applications presents some limitations related to flexibility (e.g. the possibility of running the same models with different input data sources, or different models with the same data sources) and scalability (e.g. launching several runs for different scenarios, or implementing more accurate and computing-demanding models). Flexibility can be addressed adopting a modular design based on a SOA and standard services and models, such as OWS and ISO for geospatial services. Distributed computing and storage solutions could improve scalability. Basing on such considerations an architectural framework has been defined. It is made of a Web Service layer providing advanced services for CP applications (e.g. standard geospatial data sharing and processing services) working on the underlying Grid platform. This framework has been tested through the development of prototypes as proof-of-concept. These theoretical studies and proof-of-concept demonstrated that although Grid and geospatial technologies would be able to provide significant benefits to CP applications in terms of scalability and flexibility, current platforms are designed taking into account requirements different from CP. In particular CP applications have strict requirements in terms of: a) Real

  14. Automated innovative diagnostic, data management and communication tool, for improving malaria vector control in endemic settings.

    Science.gov (United States)

    Vontas, John; Mitsakakis, Konstantinos; Zengerle, Roland; Yewhalaw, Delenasaw; Sikaala, Chadwick Haadezu; Etang, Josiane; Fallani, Matteo; Carman, Bill; Müller, Pie; Chouaïbou, Mouhamadou; Coleman, Marlize; Coleman, Michael

    2016-01-01

    Malaria is a life-threatening disease that caused more than 400,000 deaths in sub-Saharan Africa in 2015. Mass prevention of the disease is best achieved by vector control which heavily relies on the use of insecticides. Monitoring mosquito vector populations is an integral component of control programs and a prerequisite for effective interventions. Several individual methods are used for this task; however, there are obstacles to their uptake, as well as challenges in organizing, interpreting and communicating vector population data. The Horizon 2020 project "DMC-MALVEC" consortium will develop a fully integrated and automated multiplex vector-diagnostic platform (LabDisk) for characterizing mosquito populations in terms of species composition, Plasmodium infections and biochemical insecticide resistance markers. The LabDisk will be interfaced with a Disease Data Management System (DDMS), a custom made data management software which will collate and manage data from routine entomological monitoring activities providing information in a timely fashion based on user needs and in a standardized way. The ResistanceSim, a serious game, a modern ICT platform that uses interactive ways of communicating guidelines and exemplifying good practices of optimal use of interventions in the health sector will also be a key element. The use of the tool will teach operational end users the value of quality data (relevant, timely and accurate) to make informed decisions. The integrated system (LabDisk, DDMS & ResistanceSim) will be evaluated in four malaria endemic countries, representative of the vector control challenges in sub-Saharan Africa, (Cameroon, Ivory Coast, Ethiopia and Zambia), highly representative of malaria settings with different levels of endemicity and vector control challenges, to support informed decision-making in vector control and disease management.

  15. Energy systems. Tome 3: advanced cycles, low environmental impact innovative systems

    International Nuclear Information System (INIS)

    Gicquel, R.

    2009-01-01

    This third tome about energy systems completes the two previous ones by showing up advanced thermodynamical cycles, in particular having a low environmental impact, and by dealing with two other questions linked with the study of systems with a changing regime operation: - the time management of energy, with the use of thermal and pneumatic storage systems and time simulation (schedule for instance) of systems (solar energy type in particular); - the technological dimensioning and non-nominal regime operation studies. Because this last topic is particularly complex, new functionalities have been implemented mainly by using the external classes mechanism, which allows the user to freely personalize his models. This tome is illustrated with about 50 examples of cycles modelled with Thermoptim software. Content: foreword; 1 - generic external classes; 2 - advanced gas turbine cycles; 3 - evaporation-concentration, mechanical steam compression, desalination, hot gas drying; 4 - cryogenic cycles; 5 - electrochemical converters; 6 - global warming, CO 2 capture and sequestration; 7 - future nuclear reactors (coupled to Hirn and Brayton cycles); 8 - thermodynamic solar cycles; 10 - pneumatic and thermal storage; 11 - calculation of thermodynamic solar facilities; 12 - problem of technological dimensioning and non-nominal regime; 13 - exchangers modeling and parameterizing for the dimensioning and the non-nominal regime; 14 - modeling and parameterizing of volumetric compressors; 15 - modeling and parameterizing of turbo-compressors and turbines; 16 - identification methodology of component parameters; 17 - case studies. (J.S.)

  16. Passive Safety Systems in Advanced Water Cooled Reactors (AWCRS). Case Studies. A Report of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO)

    International Nuclear Information System (INIS)

    2013-09-01

    This report presents the results from the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) collaborative project (CP) on Advanced Water Cooled Reactor Case Studies in Support of Passive Safety Systems (AWCR), undertaken under the INPRO Programme Area C. INPRO was launched in 2000 - on the basis of a resolution of the IAEA General Conference (GC(44)/RES/21) - to ensure that nuclear energy is available in the 21st century in a sustainable manner, and it seeks to bring together all interested Member States to consider actions to achieve innovation. An important objective of nuclear energy system assessments is to identify 'gaps' in the various technologies and corresponding research and development (R and D) needs. This programme area fosters collaboration among INPRO Member States on selected innovative nuclear technologies to bridge technology gaps. Public concern about nuclear reactor safety has increased after the Fukushima Daiichi nuclear power plant accident caused by the loss of power to pump water for removing residual heat in the core. As a consequence, there has been an increasing interest in designing safety systems for new and advanced reactors that are passive in nature. Compared to active systems, passive safety features do not require operator intervention, active controls, or an external energy source. Passive systems rely only on physical phenomena such as natural circulation, thermal convection, gravity and self-pressurization. Passive safety features, therefore, are increasingly recognized as an essential component of the next-generation advanced reactors. A high level of safety and improved competitiveness are common goals for designing advanced nuclear power plants. Many of these systems incorporate several passive design concepts aimed at improving safety and reliability. The advantages of passive safety systems include simplicity, and avoidance of human intervention, external power or signals. For these reasons, most

  17. Improved algorithms and advanced features of the CAD to MC conversion tool McCad

    International Nuclear Information System (INIS)

    Lu, L.; Fischer, U.; Pereslavtsev, P.

    2014-01-01

    Highlights: •The latest improvements of the McCad conversion approach including decomposition and void filling algorithms is presented. •An advanced interface for the materials editing and assignment has been developed and added to the McCAD GUI. •These improvements have been tested and successfully applied to DEMO and ITER NBI (Neutral Beam Injector) applications. •The performance of the CAD model conversion process is shown to be significantly improved. -- Abstract: McCad is a geometry conversion tool developed at KIT to enable the automatic bi-directional conversions of CAD models into the Monte Carlo (MC) geometries utilized for neutronics calculations (CAD to MC) and, reversed (MC to CAD), for visualization purposes. The paper presents the latest improvements of the conversion algorithms including improved decomposition, void filling and an advanced interface for the materials editing and assignment. The new implementations and features were tested on fusion neutronics applications to the DEMO and ITER NBI (Neutral Beam Injector) models. The results demonstrate greater stability and enhanced efficiency of McCad conversion process

  18. CSAU (code scaling, applicability and uncertainty), a tool to prioritize advanced reactor research

    International Nuclear Information System (INIS)

    Wilson, G.E.; Boyack, B.E.

    1990-01-01

    Best Estimate computer codes have been accepted by the US Nuclear Regulatory Commission as an optional tool for performing safety analysis related to the licensing and regulation of current nuclear reactors producing commercial electrical power, providing their uncertainty is quantified. In support of this policy change, the NRC and its contractors and consultants have developed and demonstrated an uncertainty quantification methodology called CSAU. At the process level, the method is generic to any application which relies on best estimate computer code simulations to determine safe operating margins. The primary use of the CSAU methodology is to quantify safety margins for existing designs; however, the methodology can also serve an equally important role in advanced reactor research for plants not yet built. Applied early, during the period when alternate designs are being evaluated, the methodology can identify the relative importance of the sources of uncertainty in the knowledge of each plant behavior and, thereby, help prioritize the research needed to bring the new designs to fruition. This paper describes the CSAU methodology, at the generic process level, and provides the general principles whereby it may be applied to evaluations of advanced reactor designs. 9 refs., 1 fig., 1 tab

  19. Innovative partnerships to advance public health training in community-based academic residency programs

    Directory of Open Access Journals (Sweden)

    Lo JC

    2017-10-01

    Full Text Available Joan C Lo,1–3 Thomas E Baudendistel,2,3 Abhay Dandekar,3,4 Phuoc V Le,5 Stanton Siu,2,3 Bruce Blumberg6 1Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA; 2Department of Medicine, Kaiser Permanente Oakland Medical Center, Oakland, CA, USA; 3Graduate Medical Education, Kaiser Permanente East Bay, Oakland, CA, USA; 4Department of Pediatrics, Kaiser Permanente Oakland Medical Center, Oakland, CA, USA; 5School of Public Health, University of California Berkeley, Berkeley, CA, USA; 6Graduate Medical Education, Kaiser Permanente Northern California, Oakland, CA, USA Abstract: Collaborative partnerships between community-based academic residency ­training programs and schools of public health, represent an innovative approach to training future physician leaders in population management and public health. In Kaiser Permanente Northern California, development of residency-Masters in Public Health (MPH tracks in the Internal Medicine Residency and the Pediatrics Residency programs, with MPH graduate studies completed at the University of California Berkeley School of Public Health, enables physicians to integrate clinical training with formal education in epidemiology, biostatistics, health policy, and disease prevention. These residency-MPH programs draw on more than 50 years of clinical education, public health training, and health services research – creating an environment that sparks inquiry and added value by developing skills in patient-centered care through the lens of population-based outcomes. Keywords: graduate medical education, public health, master’s degree, internal medicine, pediatrics, residency training

  20. Comparing the Advanced REACH Tool's (ART) Estimates With Switzerland's Occupational Exposure Data.

    Science.gov (United States)

    Savic, Nenad; Gasic, Bojan; Schinkel, Jody; Vernez, David

    2017-10-01

    The Advanced REACH Tool (ART) is the most sophisticated tool used for evaluating exposure levels under the European Union's Registration, Evaluation, Authorisation and restriction of CHemicals (REACH) regulations. ART provides estimates at different percentiles of exposure and within different confidence intervals (CIs). However, its performance has only been tested on a limited number of exposure data. The present study compares ART's estimates with exposure measurements collected over many years in Switzerland. Measurements from 584 cases of exposure to vapours, mists, powders, and abrasive dusts (wood/stone and metal) were extracted from a Swiss database. The corresponding exposures at the 50th and 90th percentiles were calculated in ART. To characterize the model's performance, the 90% CI of the estimates was considered. ART's performance at the 50th percentile was only found to be insufficiently conservative with regard to exposure to wood/stone dusts, whereas the 90th percentile showed sufficient conservatism for all the types of exposure processed. However, a trend was observed with the residuals, where ART overestimated lower exposures and underestimated higher ones. The median was more precise, however, and the majority (≥60%) of real-world measurements were within a factor of 10 from ART's estimates. We provide recommendations based on the results and suggest further, more comprehensive, investigations. © The Author 2017. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

  1. Advanced Practice Nursing Committee on Process Improvement in Trauma: An Innovative Application of the Strong Model.

    Science.gov (United States)

    West, Sarah Katherine

    2016-01-01

    This article aims to summarize the successes and future implications for a nurse practitioner-driven committee on process improvement in trauma. The trauma nurse practitioner is uniquely positioned to recognize the need for clinical process improvement and enact change within the clinical setting. Application of the Strong Model of Advanced Practice proves to actively engage the trauma nurse practitioner in process improvement initiatives. Through enhancing nurse practitioner professional engagement, the committee aims to improve health care delivery to the traumatically injured patient. A retrospective review of the committee's first year reveals trauma nurse practitioner success in the domains of direct comprehensive care, support of systems, education, and leadership. The need for increased trauma nurse practitioner involvement has been identified for the domains of research and publication.

  2. Technologic advances in aural rehabilitation: applications and innovative methods of service delivery.

    Science.gov (United States)

    Sweetow, Robert W; Sabes, Jennifer Henderson

    2007-06-01

    The level of interest in aural rehabilitation has increased recently, both in clinical use and in research presentations and publications. Advances in aural rehabilitation have seen previous techniques such as speech tracking and analytic auditory training reappear in computerized forms. These new delivery methods allow for a consistent, cost-effective, and convenient training program. Several computerized aural rehabilitation programs for hearing aid wearers and cochlear implant recipients have recently been developed and were reported on at the 2006 State of the Science Conference of the Rehabilitation Engineering Research Center on Hearing Enhancement at Gallaudet University. This article reviews these programs and outlines the similarities and differences in their design. Another promising area of aural rehabilitation research is the use of pharmaceuticals in the rehabilitation process. The results from a study of the effect of d-amphetamine in conjunction with intensive aural rehabilitation with cochlear implant patients are also described.

  3. Introduction of an Evaluation Tool to Predict the Probability of Success of Companies: The Innovativeness, Capabilities and Potential Model (ICP

    Directory of Open Access Journals (Sweden)

    Michael Lewrick

    2009-05-01

    Full Text Available Successful innovation requires management and in this paper a model to help manage the innovation process is presented. This model can be used to audit the management capability to innovate and to monitor how sales increase is related to innovativeness. The model was developed from a study of companies in the high technology cluster around Munich and validated using statistical procedures. The model was found to be effective at predicting the success or otherwise of the innovation strategy pursued by the company. The use of this model and how it can be used to identify areas for improvement are documented in this paper.

  4. Innovative grinding wheel design for cost-effective machining of advanced ceramics. Phase I, final report

    Energy Technology Data Exchange (ETDEWEB)

    Licht, R.H.; Ramanath, S.; Simpson, M.; Lilley, E.

    1996-02-01

    Norton Company successfully completed the 16-month Phase I technical effort to define requirements, design, develop, and evaluate a next-generation grinding wheel for cost-effective cylindrical grinding of advanced ceramics. This program was a cooperative effort involving three Norton groups representing a superabrasive grinding wheel manufacturer, a diamond film manufacturing division and a ceramic research center. The program was divided into two technical tasks, Task 1, Analysis of Required Grinding Wheel Characteristics, and Task 2, Design and Prototype Development. In Task 1 we performed a parallel path approach with Superabrasive metal-bond development and the higher technical risk, CVD diamond wheel development. For the Superabrasive approach, Task 1 included bond wear and strength tests to engineer bond-wear characteristics. This task culminated in a small-wheel screening test plunge grinding sialon disks. In Task 2, an improved Superabrasive metal-bond specification for low-cost machining of ceramics in external cylindrical grinding mode was identified. The experimental wheel successfully ground three types of advanced ceramics without the need for wheel dressing. The spindle power consumed by this wheel during test grinding of NC-520 sialon is as much as to 30% lower compared to a standard resin bonded wheel with 100 diamond concentration. The wheel wear with this improved metal bond was an order of magnitude lower than the resin-bonded wheel, which would significantly reduce ceramic grinding costs through fewer wheel changes for retruing and replacements. Evaluation of ceramic specimens from both Tasks 1 and 2 tests for all three ceramic materials did not show evidence of unusual grinding damage. The novel CVD-diamond-wheel approach was incorporated in this program as part of Task 1. The important factors affecting the grinding performance of diamond wheels made by CVD coating preforms were determined.

  5. Advanced Artificial Science. The development of an artificial science and engineering research infrastructure to facilitate innovative computational modeling, analysis, and application to interdisciplinary areas of scientific investigation.

    Energy Technology Data Exchange (ETDEWEB)

    Saffer, Shelley (Sam) I.

    2014-12-01

    This is a final report of the DOE award DE-SC0001132, Advanced Artificial Science. The development of an artificial science and engineering research infrastructure to facilitate innovative computational modeling, analysis, and application to interdisciplinary areas of scientific investigation. This document describes the achievements of the goals, and resulting research made possible by this award.

  6. Development of a tool of probabilistic safety analysis for advanced nuclear reactors

    International Nuclear Information System (INIS)

    Hidalgo H, F.E.; Fran N, P.

    2007-01-01

    It is developing a tool to explain in a simple way in that it consists the Probabilistic Safety Analysis (APS) and at the same time to facilitate the comparison among the different designs of advanced nuclear reactors starting from their safety systems. This tool for teaching contemplates all the workspaces in an APS, but it is deepened only in what is the development of accident sequences and systems models. At the moment its have incorporated three types of advanced reactors, ABWR, ESBWR, and the HTGR and they are compared among if and with a BWR like that of Laguna Verde. This tool is carried out in Visual Basic code because it is a platform that can be used in any Windows atmosphere and for their easy programming. The system includes a tree of events developed for this purpose for a research HTGR built in Japan (HTTR) to have a point of comparison of the same one with other reactors of previous generations. It is that in the fourth generation reactors the measure of frequency of core damage doesn't make the same sense that for reactors of previous generations, which is due to its passive safety systems and its design type of the fuel, that which makes indispensable the development of another type of risk measure. The tree of events is presented for the initiator event 'the rupture of the main pipe' that causes the depressurization of the HTTR reactor. In this article it was concluded that it is necessary to evaluate the accident until reaching to the liberation of fission products that one knows in APS like an APS study level 1 and level 2 together. The final states developed starting from the possible phenomena that happen in these scenarios are presented. For this, its are considered flaws of all the mitigation systems that intervene in this accident. The tree of events developed for this work and the definition of the final states contributes to the development of as carrying out an APS for fourth generation reactors, with the purpose of developing an APS

  7. THE FLAG: A Web Resource of Innovative Assessment Tools for Faculty in College Science, Mathematics, Engineering, and Technology

    Science.gov (United States)

    Zeilik, M.; Mathieu, R. D.; National InstituteScience Education; College Level-One Team

    2000-12-01

    Even the most dedicated college faculty often discover that their students fail to learn what was taught in their courses and that much of what students do learn is quickly forgotten after the final exam. To help college faculty improve student learning in college Science, Mathematics, Engineering and Technology (SMET), the College Level - One Team of the National Institute for Science Education has created the "FLAG" a Field-tested Learning Assessment Guide for SMET faculty. Developed with funding from the National Science Foundation, the FLAG presents in guidebook format a diverse and robust collection of field-tested classroom assessment techniques (CATs), with supporting information on how to apply them in the classroom. Faculty can download the tools and techniques from the website, which also provides a goals clarifier, an assessment primer, a searchable database, and links to additional resources. The CATs and tools have been reviewed by an expert editorial board and the NISE team. These assessment strategies can help faculty improve the learning environments in their SMET courses especially the crucial introductory courses that most strongly shape students' college learning experiences. In addition, the FLAG includes the web-based Student Assessment of Learning Gains. The SALG offers a convenient way to evaluate the impact of your courses on students. It is based on findings that students' estimates of what they gained are more reliable and informative than their observations of what they liked about the course or teacher. It offers accurate feedback on how well the different aspects of teaching helped the students to learn. Students complete the SALG online after a generic template has been modified to fit the learning objectives and activities of your course. The results are presented to the teacher as summary statistics automatically. The FLAG can be found at the NISE "Innovations in SMET Education" website at www.wcer.wisc.edu/nise/cl1

  8. Local Stories Adapted as Learning Tools Innovation of Fairy Tale for Teacher to Improve the Literacy Skills of Student in Secondary Schools

    Directory of Open Access Journals (Sweden)

    Nazla Maharani Umaya

    2017-04-01

    Full Text Available One of the obstacles on the fairy tale of learning in secondary schools is there is not enough learning tool as an innovation. The example is found only one or two kind of teaching materials that use for learning, and only about 25% of the fairy tale text has from the local stories in each material. Student need more material than that to help them finish the study easily. The methods of research is exploratory mixed design. It's because the first sequent of this research is gathering qualitative data exploration for development, and collecting qualitative data to explain relationship found in the quantitative data (experimental result. An epic story is an object of the local stories chosen. All developed a tools consisting of a teacher guide, student books, and audiovisual. The result of this research is an increased literacy in students and the effectiveness of learning tools of the fairy tale for secondary school students. The conclusions is the study that the local story adapted as a learning tools innovation is effective to facilitate student learning and improve literacy skills better than regular tools. It can be a part of technical innovation competency development training of teachers in teaching. Except where otherwise noted, content on this site is licensed under a Creative Commons Attribution 4.0 International License

  9. Innovations in Primary Health Care: the use of communications technology and information tools to support local management.

    Science.gov (United States)

    Pinto, Luiz Felipe; Rocha, Cristianne Maria Famer

    2016-05-01

    Social media has been used in different contexts as a way to streamline the flow of data and information for decision making. This has contributed to the issue of knowledge production in networks and the expansion of communication channels so that there is greater access to health services. This article describes the results of research done on 16 Information Technology and Communications Observatories in Health Care - OTICS Network in Rio - covering the Municipal Health Secretariat in Rio de Janeiro which supported the integration of primary health care and promoted the monitoring of health. It is a descriptive case study. The results relate to the support given to employees in training covering the dissemination of information, communication, training and information management in primary health care. This innovative means of communication in public health, with very little cost to the Unified Health System (SUS), allowed for a weekly registering of work processes for teams that worked in 193 primary health care units (APS) using blogs, whose total accesses reached the seven million mark in mid-2015. In the future there is a possibility that distance learning tools could be used to assist in training processes and in the continuing education of professionals in family health teams.

  10. Innovative practice: exploring acculturation theory to advance rehabilitation from pediatric to adult "cultures" of care.

    Science.gov (United States)

    Nguyen, Tram; Baptiste, Sue

    2015-01-01

    This perspective paper explores the application of acculturation and the inherent concepts and ideas associated with this theory in rehabilitation to provide a framework for interpreting patient circumstances, responses and behaviours as they move from one culture to the next. Traditionally acculturation theory has been use to examine changes in culture in an ethnic or country sense, however, this paper is among the first to apply acculturation theory to the rehabilitation service cultures from pediatric to adult care for youth with chronic health conditions. The objectives of this paper are threefold: (1) to critically appraise key literature in the development of acculturation theory, (2) to discuss how acculturation theory can be applied in rehabilitation practice through a clinical vignette, and finally (3) to discuss how acculturation theory can advance rehabilitation by enhancing client-centered practice. Acculturation theory can provide insight into how patients are experiencing a change in health care "cultures", in the context of their overarching life circumstances. This, coming from a broader societal perspective can in turn inform an optimal approach to client-centered practice, and the application of rehabilitation-specific team inputs. This theoretical framework can heighten practitioners' awareness of patients' unique worldviews related to their expectations for care and treatment thus reducing fear of diversity to establish positive partnerships between patients and clinicians. An understanding of patients' acculturation processes will add new insight into how we can best deliver services and supports to optimise health, opportunities and experiences for youth with chronic conditions.

  11. The DNP/MPH Dual Degree: An Innovative Graduate Education Program for Advanced Public Health Nursing.

    Science.gov (United States)

    Shaw, Kathy; Harpin, Scott; Steinke, Geraldine; Stember, Marilyn; Krajicek, Marilyn

    2017-03-01

    Strong professional priorities, evolving Affordable Care Act requirements, and a significantly limited public health nursing workforce prompted the University of Colorado College of Nursing to collaborate with the School of Public Health to implement one of the first Doctor of Nursing Practice/Master of Public Health dual degree programs in the nation. Federal grant funding supported the development, implementation, and evaluation of this unique post-baccalaureate dual degree program, for which there were no roadmaps, models, or best practices to follow. Several key issues emerged that serve as lessons learned in creating a new, novel higher education pathway for Advanced Public Health Nursing. This paper highlights two of those: (1) marketing, admission, and matriculation across two programs, and (2) enhancing curricula through distance coursework and interprofessional education. When collaboration with a school of public health is possible, the Doctor of Nursing Practice/Master of Public Health dual degree is an efficient way to prepare public health nurses' with the highest level of public health knowledge, practice, and leadership expertise. © 2016 Wiley Periodicals, Inc.

  12. Advancing the Frontiers in Nanocatalysis, Biointerfaces, and Renewable Energy Conversion by Innovations of Surface Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Somorjai, G.A.; Frei, H.; Park, J.Y.

    2009-07-23

    The challenge of chemistry in the 21st century is to achieve 100% selectivity of the desired product molecule in multipath reactions ('green chemistry') and develop renewable energy based processes. Surface chemistry and catalysis play key roles in this enterprise. Development of in situ surface techniques such as high-pressure scanning tunneling microscopy, sum frequency generation (SFG) vibrational spectroscopy, time-resolved Fourier transform infrared methods, and ambient pressure X-ray photoelectron spectroscopy enabled the rapid advancement of three fields: nanocatalysts, biointerfaces, and renewable energy conversion chemistry. In materials nanoscience, synthetic methods have been developed to produce monodisperse metal and oxide nanoparticles (NPs) in the 0.8-10 nm range with controlled shape, oxidation states, and composition; these NPs can be used as selective catalysts since chemical selectivity appears to be dependent on all of these experimental parameters. New spectroscopic and microscopic techniques have been developed that operate under reaction conditions and reveal the dynamic change of molecular structure of catalysts and adsorbed molecules as the reactions proceed with changes in reaction intermediates, catalyst composition, and oxidation states. SFG vibrational spectroscopy detects amino acids, peptides, and proteins adsorbed at hydrophobic and hydrophilic interfaces and monitors the change of surface structure and interactions with coadsorbed water. Exothermic reactions and photons generate hot electrons in metal NPs that may be utilized in chemical energy conversion. The photosplitting of water and carbon dioxide, an important research direction in renewable energy conversion, is discussed.

  13. Crossdisciplinary fundamental research--the seed for scientific advance and technological innovation.

    Science.gov (United States)

    Kroto, Harold

    2011-12-28

    As it was earlier in the 1980's, so it is now, fundamental science research is under threat as decisions are made on science funding by people who do not do fundamental research, seem congenitally incapable of understanding what it is and furthermore in the face of countless examples seem blind to how important it has been to the technologies that govern our modern life and will be to the future technologies that we desperately need to develop to survive. In this article some general observations are made on how the fascination for what happens in space and stars was the key trigger that gave birth to Science itself and a particular case is outlined which indicates that this same fascination is still the catalyst of some fundamental breakthroughs today. This article also outlines an archetypal example of the way major breakthroughs are often made by the synergy that comes from cross-disciplinary research in a way which is totally surprising. In this case it started from a curiosity about the quantum mechanical description of molecular dynamics and involved pioneering advances in synthetic organic chemistry which led to the suprising discovery that some exotic carbon molecules were abundant in space and stars. These results initiated an experiment using a new technology that represented a major breakthrough in cluster science. The upshot was totally unpredictable, the birth of a whole new field of Chemistry as well as a paradigm shift in major areas of Nanoscience and Nanotechnology.

  14. Frugal innovation in medicine for low resource settings

    OpenAIRE

    Tran , Viet-Thi; Ravaud , Philippe

    2016-01-01

    International audience; Whilst it is clear that technology is crucial to advance healthcare: innovation in medicine is not just about high-tech tools, new procedures or genome discoveries. In constrained environments, healthcare providers often create unexpected solutions to provide adequate healthcare to patients. These inexpensive but effective frugal innovations may be imperfect, but they have the power to ensure that health is within reach of everyone. Frugal innovations are not limited t...

  15. Preclinical models for an innovative glioblastoma therapeutical strategy by 188Re-SSS encapsulated in nano-tools: translational view

    International Nuclear Information System (INIS)

    Cikankowitz, A.; Belloche, C.; Verger, E.; Garcion, E.; Hindre, F.; Chassain, G.; Fellah, B.; Abadie, J.; Chouin, N.; Ibisch, C.; Davodeau, F.; Couez, D.; Lepareur, N.; Lacoeuille, F.; Menei, P.

    2015-01-01

    Full text of publication follows. Aim: Glioblastoma (GBM) is the most frequent cancer of the nervous system and therapies currently used cannot treat definitively this disease. By the way of NucSan (Nuclear for health) program which supports research development about the use of radio pharmaceutics in oncology, the aim of the proposed work is to provide evidences that internal radiotherapy through lipid nanocapsules loaded with Rhenium-188 (LNC 188 Re-SSS) is an alternative therapeutic strategy for GBM that can be translated to human medicine. Previous works have shown a remarkable efficiency of this tool among syngeneic rats linked with local and peripheral recruitments of the immune system's effectors. In this context, two animal models have been chosen to validate the feasibility of this new innovative therapy design (LNC 188 Re-SSS stereotactic injection). Materials and methods: the syngeneic six weeks old C57BL/6J female mice were treated 6 or 12 days after stereotactic GL261 cells implantation, by a single injection of increasing activities of LNC 188 Re-SSS (0,925; 1,85 and 2,7 MBq/5μl). MRI was used to follow tumor progression to determine the mass volume through the selection of regions of interest. The increased median survival time (IMST) was also assessed for treated mice versus control mice (stereotactic injection of saline solution). For long time survival animals (3 times the median survival time), they were rechallenged through the same procedure in the other hemisphere. The brachy-cephalic dog bearing spontaneous tumor will lead to additional evidences to specifically highlight the potential of this innovative technology for GBM treatment. In order to validate procedures of intracerebral injections, a stereotactic head frame specially designed for dog has been conceived which allow both images acquisition (MRI-SPECT and PET) and the achievement of biopsies. Results/Perspectives: as previously observed on rat models, the preliminary data show

  16. NASA Advanced Concepts Office, Earth-To-Orbit Team Design Process and Tools

    Science.gov (United States)

    Waters, Eric D.; Garcia, Jessica; Threet, Grady E., Jr.; Phillips, Alan

    2013-01-01

    The Earth-to-Orbit Team (ETO) of the Advanced Concepts Office (ACO) at NASA Marshall Space Flight Center (MSFC) is considered the pre-eminent "go-to" group for pre-phase A and phase A concept definition. Over the past several years the ETO team has evaluated thousands of launch vehicle concept variations for a significant number of studies including agency-wide efforts such as the Exploration Systems Architecture Study (ESAS), Constellation, Heavy Lift Launch Vehicle (HLLV), Augustine Report, Heavy Lift Propulsion Technology (HLPT), Human Exploration Framework Team (HEFT), and Space Launch System (SLS). The ACO ETO Team is called upon to address many needs in NASA's design community; some of these are defining extremely large trade-spaces, evaluating advanced technology concepts which have not been addressed by a large majority of the aerospace community, and the rapid turn-around of highly time critical actions. It is the time critical actions, those often limited by schedule or little advanced warning, that have forced the five member ETO team to develop a design process robust enough to handle their current output level in order to meet their customer's needs. Based on the number of vehicle concepts evaluated over the past year this output level averages to four completed vehicle concepts per day. Each of these completed vehicle concepts includes a full mass breakdown of the vehicle to a tertiary level of subsystem components and a vehicle trajectory analysis to determine optimized payload delivery to specified orbital parameters, flight environments, and delta v capability. A structural analysis of the vehicle to determine flight loads based on the trajectory output, material properties, and geometry of the concept is also performed. Due to working in this fast-paced and sometimes rapidly changing environment, the ETO Team has developed a finely tuned process to maximize their delivery capabilities. The objective of this paper is to describe the interfaces

  17. Advances in In Vitro and In Silico Tools for Toxicokinetic Dose ...

    Science.gov (United States)

    Recent advances in vitro assays, in silico tools, and systems biology approaches provide opportunities for refined mechanistic understanding for chemical safety assessment that will ultimately lead to reduced reliance on animal-based methods. With the U.S. commercial chemical landscape encompassing thousands of chemicals with limited data, safety assessment strategies that reliably predict in vivo systemic exposures and subsequent in vivo effects efficiently are a priority. Quantitative in vitro-in vivo extrapolation (QIVIVE) is a methodology that facilitates the explicit and quantitative application of in vitro experimental data and in silico modeling to predict in vivo system behaviors and can be applied to predict chemical toxicokinetics, toxicodynamics and also population variability. Tiered strategies that incorporate sufficient information to reliably inform the relevant decision context will facilitate acceptance of these alternative data streams for safety assessments. This abstract does not necessarily reflect U.S. EPA policy. This talk will provide an update to an international audience on the state of science being conducted within the EPA’s Office of Research and Development to develop and refine approaches that estimate internal chemical concentrations following a given exposure, known as toxicokinetics. Toxicokinetic approaches hold great potential in their ability to link in vitro activities or toxicities identified during high-throughput screen

  18. The O3E program: Innovative educational and communication tools for better face natural hazards and emergencies

    Science.gov (United States)

    Berenguer, Jean Luc; Solarino, Stefano; Corboulex, Françoise; Ponzone, Monica; Cremonini, Roberto; Eva, Claudio; Eva, Elena; Ferretti, Gabriele; Leputh, Jessica; Barroux, Emmanuel; Sornette, Anne; Luyet, Vincent; Bosset, Henry

    2010-05-01

    As dramatically reminded during the last days by the Haiti disaster, earthquakes are traumatic events as storms or floods. They cause more damages when population don't have the knowledge of these phenomena and doesn't know how to deal with it. Presently, it's not possible to predict an earthquakes or extreme meteorological events. Preparation stay the best and efficient way to save life. Education and training are two essential ingredients to help the population to perceive the scientific information formerly confined in the laboratories, in particular in the domain of the environmental risk. The "O3E" innovative Project (European Observatory for Education and Environment) is established after 10 years (1997-2007) of regional, national and international programs ("Sismos of the Schools", "Rinamed Medocc"), and from Italian and Swiss experiences concerning environment tools for education. This project with cooperation between scientists of France, Italy and Switzerland, is born to promote a responsible behavior of young citizens by means of scientific information about natural risks. ARGAL (Agency for Geological Risk in the Latin Arc - France) operates the administrative and technical coordination. The first innovative output of O3E is the creation of a school network in the Alpine and Mediterranean areas equipped with environmental sensors installed direct into the educational buildings. The data by seismometers, weather stations, river's flows and soil moisture, recorded in the schools and processed by the students, are collected on dedicated servers and then made available through a internet platform to the entire educational community. By means of coordinated activities of critical analysis of data, their comparison with the information available through other media, the awareness about the importance of knowledge and evaluation of reliable data about their own territory is promoted. This equipment's network "O3E," is the starting point of many other activities

  19. Use of an Innovative Personality-Mindset Profiling Tool to Guide Culture-Change Strategies among Different Healthcare Worker Groups.

    Science.gov (United States)

    Grayson, M Lindsay; Macesic, Nenad; Huang, G Khai; Bond, Katherine; Fletcher, Jason; Gilbert, Gwendolyn L; Gordon, David L; Hellsten, Jane F; Iredell, Jonathan; Keighley, Caitlin; Stuart, Rhonda L; Xuereb, Charles S; Cruickshank, Marilyn

    2015-01-01

    Important culture-change initiatives (e.g. improving hand hygiene compliance) are frequently associated with variable uptake among different healthcare worker (HCW) categories. Inherent personality differences between these groups may explain change uptake and help improve future intervention design. We used an innovative personality-profiling tool (ColourGrid®) to assess personality differences among standard HCW categories at five large Australian hospitals using two data sources (HCW participant surveys [PS] and generic institution-wide human resource [HR] data) to: a) compare the relative accuracy of these two sources; b) identify differences between HCW groups and c) use the observed profiles to guide design strategies to improve uptake of three clinically-important initiatives (improved hand hygiene, antimicrobial stewardship and isolation procedure adherence). Results from 34,243 HCWs (HR data) and 1045 survey participants (PS data) suggest that HCWs were different from the general population, displaying more individualism, lower power distance, less uncertainty avoidance and greater cynicism about advertising messages. HR and PS data were highly concordant in identifying differences between the three key HCW categories (doctors, nursing/allied-health, support services) and predicting appropriate implementation strategies. Among doctors, the data suggest that key messaging should differ between full-time vs part-time (visiting) senior medical officers (SMO, VMO) and junior hospital medical officers (HMO), with SMO messaging focused on evidence-based compliance, VMO initiatives emphasising structured mandatory controls and prestige loss for non-adherence, and for HMOs focusing on leadership opportunity and future career risk for non-adherence. Compared to current standardised approaches, targeted interventions based on personality differences between HCW categories should result in improved infection control-related culture-change uptake. Personality

  20. Use of an Innovative Personality-Mindset Profiling Tool to Guide Culture-Change Strategies among Different Healthcare Worker Groups.

    Directory of Open Access Journals (Sweden)

    M Lindsay Grayson

    Full Text Available Important culture-change initiatives (e.g. improving hand hygiene compliance are frequently associated with variable uptake among different healthcare worker (HCW categories. Inherent personality differences between these groups may explain change uptake and help improve future intervention design.We used an innovative personality-profiling tool (ColourGrid® to assess personality differences among standard HCW categories at five large Australian hospitals using two data sources (HCW participant surveys [PS] and generic institution-wide human resource [HR] data to: a compare the relative accuracy of these two sources; b identify differences between HCW groups and c use the observed profiles to guide design strategies to improve uptake of three clinically-important initiatives (improved hand hygiene, antimicrobial stewardship and isolation procedure adherence.Results from 34,243 HCWs (HR data and 1045 survey participants (PS data suggest that HCWs were different from the general population, displaying more individualism, lower power distance, less uncertainty avoidance and greater cynicism about advertising messages. HR and PS data were highly concordant in identifying differences between the three key HCW categories (doctors, nursing/allied-health, support services and predicting appropriate implementation strategies. Among doctors, the data suggest that key messaging should differ between full-time vs part-time (visiting senior medical officers (SMO, VMO and junior hospital medical officers (HMO, with SMO messaging focused on evidence-based compliance, VMO initiatives emphasising structured mandatory controls and prestige loss for non-adherence, and for HMOs focusing on leadership opportunity and future career risk for non-adherence.Compared to current standardised approaches, targeted interventions based on personality differences between HCW categories should result in improved infection control-related culture-change uptake. Personality

  1. Advanced Modeling Tools for Controlling Complex Assets Across Time Delay, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed innovation is a hybrid simulation module to replace the current "Behavioral Sim" in JSC's Predictive Interactive Graphical Interface (PIGI). PIGI helps...

  2. A Labview System with Novel and Advanced Prognostic Tools, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose a portable data acquisition and prognostic system that contains both hardware and software with several innovative ideas. First, our hardware system...

  3. Advanced Analytical Tools for the Characterization of Fundamental Jet Noise Sources and Structures, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — There is a need for innovative technologies and methods for noise reduction, noise prediction, and noise diagnostics. A comprehensive approach to reducing noise from...

  4. How Project Management Tools Aid in Association to Advance Collegiate Schools of Business (AACSB) International Maintenance of Accreditation

    Science.gov (United States)

    Cann, Cynthia W.; Brumagim, Alan L.

    2008-01-01

    The authors present the case of one business college's use of project management techniques as tools for accomplishing Association to Advance Collegiate Schools of Business (AACSB) International maintenance of accreditation. Using these techniques provides an efficient and effective method of organizing maintenance efforts. In addition, using…

  5. Advances in In Vitro and In Silico Tools for Toxicokinetic Dose Modeling and Predictive Toxicology (WC10)

    Science.gov (United States)

    Recent advances in vitro assays, in silico tools, and systems biology approaches provide opportunities for refined mechanistic understanding for chemical safety assessment that will ultimately lead to reduced reliance on animal-based methods. With the U.S. commercial chemical lan...

  6. Gamma-gamma density and lithology tools simulation based on GEANT4 advanced low energy Compton scattering (GALECS) package

    International Nuclear Information System (INIS)

    Esmaeili-sani, Vahid; Moussavi-zarandi, Ali; Boghrati, Behzad; Afarideh, Hossein

    2012-01-01

    Geophysical bore-hole data represent the physical properties of rocks, such as density and formation lithology, as a function of depth in a well. Properties of rocks are obtained from gamma ray transport logs. Transport of gamma rays, from a 137 Cs point gamma source situated in a bore-hole tool, through rock media to detectors, has been simulated using a GEANT4 radiation transport code. The advanced Compton scattering concepts were used to gain better analyses about well formation. The simulation and understanding of advanced Compton scattering highly depends on how accurately the effects of Doppler broadening and Rayleigh scattering are taken into account. A Monte Carlo package that simulates the gamma-gamma well logging tools based on GEANT4 advanced low energy Compton scattering (GALECS).

  7. Gamma-gamma density and lithology tools simulation based on GEANT4 advanced low energy Compton scattering (GALECS) package

    Energy Technology Data Exchange (ETDEWEB)

    Esmaeili-sani, Vahid, E-mail: vaheed_esmaeely80@yahoo.com [Department of Nuclear Engineering and Physics, Amirkabir University of Technology, P.O. Box 4155-4494, Tehran (Iran, Islamic Republic of); Moussavi-zarandi, Ali; Boghrati, Behzad; Afarideh, Hossein [Department of Nuclear Engineering and Physics, Amirkabir University of Technology, P.O. Box 4155-4494, Tehran (Iran, Islamic Republic of)

    2012-02-01

    Geophysical bore-hole data represent the physical properties of rocks, such as density and formation lithology, as a function of depth in a well. Properties of rocks are obtained from gamma ray transport logs. Transport of gamma rays, from a {sup 137}Cs point gamma source situated in a bore-hole tool, through rock media to detectors, has been simulated using a GEANT4 radiation transport code. The advanced Compton scattering concepts were used to gain better analyses about well formation. The simulation and understanding of advanced Compton scattering highly depends on how accurately the effects of Doppler broadening and Rayleigh scattering are taken into account. A Monte Carlo package that simulates the gamma-gamma well logging tools based on GEANT4 advanced low energy Compton scattering (GALECS).

  8. A study of the development of critical thinking skills using an innovative web 2.0 tool.

    Science.gov (United States)

    Eales-Reynolds, Lesley-Jane; Gillham, David; Grech, Carol; Clarke, Colin; Cornell, Jacqueline

    2012-10-01

    Healthcare educators face numerous challenges including technological change, information overload, and the need to maintain clinical expertise and research knowledge across multiple specialities. Students also need to develop their capacity for critical thinking, using and discriminating between diverse sources of knowledge in order to advance their own practice. To investigate student perceptions of the affordances of a novel web 2.0-based tool--the Web Resource Appraisal Process (WRAP), designed to support the development of critical thinking skills, and to identify how student's understanding of critical thinking and their use of web 2.0 resources might inform the cross-disciplinary development of the WRAP. A two phase, action research study of student perceptions of the WRAP and their ability to source and identify valid information sources. Implemented at the University of South Australia, development of the WRAP is an international project with the University of Westminster, UK. Students from international locations participated in the project. A mixed methods approach was adopted involving a two phase action research study. In phase one, student perceptions of the WRAP were obtained using a modified course feedback questionnaire. This informed the development of a subsequent questionnaire used to survey student perceptions of their usage of online resources, the ease of access of such resources and their approaches to determining their validity. Results suggest that students mainly use traditional resources when preparing work for assessment and they either do not understand the concept of, or do not exercise, critical thinking skills in such activities. However, the feedback from students using the WRAP, demonstrated that they found it instructive and useful. To ensure that practice developments are based on authoritative evidence, students need to develop critical thinking skills which may be facilitated by tools such as the WRAP. Crown Copyright © 2012

  9. Mobilization for energy renovation. Innovative tools for the uptake of deep renovation of the existing building stock based on behavioural insights

    OpenAIRE

    Taranu, Victoria; Verbeeck, Griet

    2015-01-01

    Mobilization for energy renovation. Innovative tools for the uptake of deep renovation of the existing building stock based on behavioural insights. In the context of climate change it is a priority to reduce the energy demand and make a shift towards renewable sources of energy. In Flanders almost half of the existing residential building stock was built before 1970 with low levels of insulation and inefficient installations. The vast majority of Fle...

  10. Image Montaging for Creating a Virtual Pathology Slide: An Innovative and Economical Tool to Obtain a Whole Slide Image.

    Science.gov (United States)

    Banavar, Spoorthi Ravi; Chippagiri, Prashanthi; Pandurangappa, Rohit; Annavajjula, Saileela; Rajashekaraiah, Premalatha Bidadi

    2016-01-01

    Background . Microscopes are omnipresent throughout the field of biological research. With microscopes one can see in detail what is going on at the cellular level in tissues. Though it is a ubiquitous tool, the limitation is that with high magnification there is a small field of view. It is often advantageous to see an entire sample at high magnification. Over the years technological advancements in optics have helped to provide solutions to this limitation of microscopes by creating the so-called dedicated "slide scanners" which can provide a "whole slide digital image." These scanners can provide seamless, large-field-of-view, high resolution image of entire tissue section. The only disadvantage of such complete slide imaging system is its outrageous cost, thereby hindering their practical use by most laboratories, especially in developing and low resource countries. Methods . In a quest for their substitute, we tried commonly used image editing software Adobe Photoshop along with a basic image capturing device attached to a trinocular microscope to create a digital pathology slide. Results . The seamless image created using Adobe Photoshop maintained its diagnostic quality. Conclusion . With time and effort photomicrographs obtained from a basic camera-microscope set up can be combined and merged in Adobe Photoshop to create a whole slide digital image of practically usable quality at a negligible cost.

  11. Nanotechnology solutions for Alzheimer's disease: advances in research tools, diagnostic methods and therapeutic agents.

    Science.gov (United States)

    Nazem, Amir; Mansoori, G Ali

    2008-03-01

    A century of research has passed since the discovery and definition of Alzheimer's disease (AD), the primary common dementing disorder worldwide. However, AD lacks definite diagnostic approaches and effective cure at the present. Moreover, the currently available diagnostic tools are not sufficient for an early screening of AD in order to start preventive approaches. Recently the emerging field of nanotechnology has promised new techniques to solve some of the AD challenges. Nanotechnology refers to the techniques of designing and manufacturing nanosize (1-100 nm) structures through controlled positional and/or self-assembly of atoms and molecules. In this report, we present the promises that nanotechnology brings in research on the AD diagnosis and therapy. They include its potential for the better understanding of the AD root cause molecular mechanisms, AD's early diagnoses, and effective treatment. The advances in AD research offered by the atomic force microscopy, single molecule fluorescence microscopy and NanoSIMS microscopy are examined here. In addition, the recently proposed applications of nanotechnology for the early diagnosis of AD including bio-barcode assay, localized surface plasmon resonance nanosensor, quantum dot and nanomechanical cantilever arrays are analyzed. Applications of nanotechnology in AD therapy including neuroprotections against oxidative stress and anti-amyloid therapeutics, neuroregeneration and drug delivery beyond the blood brain barrier (BBB) are discussed and analyzed. All of these applications could improve the treatment approach of AD and other neurodegenerative diseases. The complete cure of AD may become feasible by a combination of nanotechnology and some other novel approaches, like stem cell technology.

  12. Advanced Differential Radar Interferometry (A-DInSAR) as integrative tool for a structural geological analysis

    Science.gov (United States)

    Crippa, B.; Calcagni, L.; Rossi, G.; Sternai, P.

    2009-04-01

    Advanced Differential SAR interferometry (A-DInSAR) is a technique monitoring large-coverage surface deformations using a stack of interferograms generated from several complex SLC SAR images, acquired over the same target area at different times. In this work are described the results of a procedure to calculate terrain motion velocity on highly correlated pixels (E. Biescas, M. Crosetto, M. Agudo, O. Monserrat e B. Crippa: Two Radar Interferometric Approaches to Monitor Slow and Fast Land Deformation, 2007) in two area Gemona - Friuli, Northern Italy, Pollino - Calabria, Southern Italy, and, furthermore, are presented some consideration, based on successful examples of the present analysis. The choice of these pixels whose displacement velocity is calculated depends on the dispersion index value (DA) or using coherence values along the stack interferograms. A-DInSAR technique allows to obtain highly reliable velocity values of the vertical displacement. These values concern the movement of minimum surfaces of about 80m2 at the maximum resolution and the minimum velocity that can be recognized is of the order of mm/y. Because of the high versatility of the technology, because of the large dimensions of the area that can be analyzed (of about 10000Km2) and because of the high precision and reliability of the results obtained, we think it is possible to exploit radar interferometry to obtain some important information about the structural context of the studied area, otherwise very difficult to recognize. Therefore we propose radar interferometry as a valid investigation tool whose results must be considered as an important integration of the data collected in fieldworks.

  13. High resolution X-ray emission spectroscopy: An advanced tool for actinide research

    Science.gov (United States)

    Vitova, T.; Brendebach, B.; Dardenne, K.; Denecke, M. A.; Lebid, A.; Löble, M.; Rothe, J.; Batuk, O. N.; Hormes, J.; Liu, D.; Breher, F.; Geckeis, H.

    2010-03-01

    High resolution X-ray emission spectroscopy (HRXES) is becoming increasingly important for our understanding of electronic and coordination structures. The combination of such information with development of quantum theoretical tools will advance our capability for predicting reactivity and physical behavior especially of 5f elements. HRXES can be used to remove lifetime broadening by registering the partial fluorescence yield emitted by the sample (i.e., recording a windowed signal from the energy dispersed fluorescence emission while varying incident photon energy), thereby yielding highly resolved X-ray absorption fine structure (XAFS) spectra. Such spectra often display resonant features not observed in conventional XAFS. The spectrometer set-up can also be used for a wide range of other experiments, for example, resonant inelastic X-ray scattering (RIXS), where bulk electron configuration information in solids, liquids and gases is obtained. Valence-selective XAFS studies, where the local structure of a selected element's valence state present in a mixture of valence states can be obtained, as well as site-selective XAFS studies, where the coordination structure of a metal bound to selected elements can be differentiated from that of all the other ligating atoms. A HRXES spectrometer has been constructed and is presently being commissioned for use at the INE-Beamline for actinide research at the synchrotron source ANKA at FZK. We present the spectrometer's compact, modular design, optimized for attaining a wide range of energies, and first test measurement results. Examples from HRXES studies of lanthanides, actinides counter parts, are also shown.

  14. Innovation: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  15. Effects of the Advanced Innovative Internet-Based Communication Education Program on Promoting Communication Between Nurses and Patients With Dementia.

    Science.gov (United States)

    Chao, Hui-Chen; Kaas, Merrie; Su, Ying-Hwa; Lin, Mei-Feng; Huang, Mei-Chih; Wang, Jing-Jy

    2016-06-01

    Effective communication between nurses and patients with dementia promotes the quality of patient care by improving the identification of patient needs and by reducing the miscommunication-related frustration of patients and nurses. This study evaluates the effects of an advanced innovative Internet-based communication education (AIICE) program on nurses' communication knowledge, attitudes, frequency of assessing patient communication capacity, and communication performance in the context of care for patients with dementia. In addition, this study attempts to evaluate the indirect effects of this program on outcomes for patients with dementia, including memory and behavior-related problems and depressive symptoms. A quasi-experimental research design with a one-group repeated measure was conducted. Convenience sampling was used to recruit nurses from long-term care facilities in southern Taiwan. Data were analyzed using general estimating equations to compare changes over time across three points: baseline, fourth-week posttest, and 16th-week posttest. One hundred five nurses completed the AIICE program and the posttest surveys. The findings indicate that nurses' communication knowledge, frequency in assessing patients' communication capacity, and communication performance had improved significantly over the baseline by either the 4th- or 16th-week posttest (p < .01). However, communication attitude showed no significant improvement in the posttest survey (p = .40). Furthermore, the findings indicate that the memory and behavior-related problems and the depressive symptoms of patients had decreased significantly by the 16th-week posttest (p = .05). This study showed that the AIICE program improves nurses' communication knowledge, frequency to assess patients' communication capacity, and communication performance and alleviates the memory and behavior-related problems and depressive symptoms of patients. The continuous communication training of nurses using the

  16. Advancing Clouds Lifecycle Representation in Numerical Models Using Innovative Analysis Methods that Bridge ARM Observations and Models Over a Breadth of Scales

    Energy Technology Data Exchange (ETDEWEB)

    Kollias, Pavlos [McGill Univ., Montreal, QC (Canada

    2016-09-06

    This the final report for the DE-SC0007096 - Advancing Clouds Lifecycle Representation in Numerical Models Using Innovative Analysis Methods that Bridge ARM Observations and Models Over a Breadth of Scales - PI: Pavlos Kollias. The final report outline the main findings of the research conducted using the aforementioned award in the area of cloud research from the cloud scale (10-100 m) to the mesoscale (20-50 km).

  17. Approach to the open advanced facilities initiative for innovation (strategic use by industry) at the University of Tsukuba, Tandem Accelerator Complex

    International Nuclear Information System (INIS)

    Sasa, K.; Tagishi, Y.; Naramoto, H.; Kudo, H.; Kita, E.

    2010-01-01

    The University of Tsukuba, Tandem Accelerator Complex (UTTAC) possesses the 12UD Pelletron tandem accelerator and the 1 MV Tandetron accelerator for University's inter-department education research. We have actively advanced collaborative researches with other research institutes and industrial users. Since the Open Advanced Facilities Initiative for Innovation by the Ministry of Education, Culture, Sports, Science and Technology started in 2007, 12 industrial experiments have been carried out at the UTTAC. This report describes efforts by University's accelerator facility to get industrial users. (author)

  18. Benefits Innovations in Employee Behavioral Health.

    Science.gov (United States)

    Sherman, Bruce; Block, Lori

    2017-01-01

    More and more employers recognize the business impact of behavioral health concerns in the workplace. This article provides insights into some of the current innovations in behavioral health benefits, along with their rationale for development. Areas of innovation include conceptual and delivery models, technological advance- ments, tools for engaging employees and ways of quantifying the business value of behavioral health benefits. The rapid growth of innovative behavioral health services should provide employers with confidence that they can tailor a program best suited to their priorities, organizational culture and cost limitations.

  19. Advance directives as a tool to respect patients' values and preferences: discussion on the case of Alzheimer's disease.

    Science.gov (United States)

    Porteri, Corinna

    2018-02-20

    The proposal of the new criteria for the diagnosis of Alzheimer's disease (AD) based on biomarker data is making possible a diagnosis of AD at the mild cognitive impairment (MCI) or predementia/prodromal- stage. Given the present lack of effective treatments for AD, the opportunity for the individuals to personally take relevant decisions and plan for their future before and if cognitive deterioration occurs is one the main advantages of an early diagnosis. Advance directives are largely seen as an effective tool for planning medical care in the event the subject becomes incompetent. Nevertheless, their value has been questioned with regard to people with dementia by scholars who refer to the arguments of personal identity and of patient's changing interests before and after the onset of dementia. In this paper, I discuss the value of advance directives in Alzheimer's disease and other kind of dementia. Despite critics, I argue that advance directives are especially advisable in dementia and provide reasons in favor of their promotion at an early stage of the disease as a valuable tool to respect patients' values and preferences on medical treatment, including participation in research and end of life decisions. I mainly support advance directives that include both decisions regarding health care and the appointment of an attorney in fact. I conclude that patients with AD at a prodromal or early stage should be offered the opportunity to execute an advance directive, and that not to honor a demented individual's directive would be an unacceptable form of discrimination towards those patients.

  20. THE INTERNATIONAL EXPERIENCE OF INTERACTION BETWEEN GOVERNMENT AND BUSINESS IN THE SPHERE OF INNOVATION: NEW TOOLS FOR INDUSTRIAL DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Anastasiya Yurievna Nikitaeva

    2015-09-01

    Full Text Available The article is devoted to the study of international experience of interaction between government and business in the innovative development of the industrial sector. Purpose of the paper is to determine the features and content of the new mechanisms of industrial development, based on integration platform of economic agents’ partnership.Methodology. The complex of system, synergy, institutional, evolutionary, and endogenous approaches is used as a methodological basis of research. Methodological apparatus of the article is presented by methods of the analysis, synthesis, abstraction, logical generalization.Results: the assessment of influence of government and commercial structures partnership on the innovative industrial development is given; the tendency of expansion of a partnership segment in the innovative sphere of the industry is empirically illustrated; features and key technologies of the new integration mechanism of industrial development are given.Conclusion: complication of innovative processes in combination with other factors results in expediency of development of partnership of economic entities in the sphere of industrial development. The extent and effectiveness of partnership practices in innovation is largely determined by the role of state institutions. For innovation of industrial development it is expedient to form the mechanisms using the integrated capacity of public and private institutions.Practical implications: the results of the study can be used in the justification of the priorities and measures of the state innovation and industrial policy, the development of concepts and programs of clustering of the regions and the development of public-private partnerships, and also formation of strategy of development of industrial structures.

  1. Real-time potentiometric sensor; an innovative tool for monitoring hydrolysis of chemo/bio-degradable drugs in pharmaceutical sciences.

    Science.gov (United States)

    Ma'mun, Ahmed; Abd El-Rahman, Mohamed K; Abd El-Kawy, Mohamed

    2018-05-30

    In recent years, the whole field of ion-selective electrodes(ISEs) in pharmaceutical sciences has expanded far beyond its original roots. The diverse range of opportunities offered by ISEs was broadly used in a number of pharmaceutical applications, with topics presented ranging from bioanalysis of drugs and metabolites, to protein binding studies, green analytical chemistry, impurity profiling, and drug dissolution in biorelevant media. Inspired from these advances and with the aim of extending the functional capabilities of ISEs, the primary focus of the present paper is the utilization of ISE as a tool in personalized medicine. Given the opportunity to explore biological events in real-time (such as drug metabolism) could be central to personalized medicine. (ATR) is a chemo-degradable and bio-degradable pharmaceutically active drug. Laudanosine (LDS) is the major degradation product and metabolite of ATR and is potentially toxic and reported to possess epileptogenic activity which increases the risk of convulsive effects. In this work, ATR have been subjected to both chemical and biological hydrolysis, and the course of the reactions is monitored by means of a ISE. In this study, we have designed an efficient real-time tracking strategy which substantially resolve the challenges of the ATR chemical and biological degradation kinetics. By utilizing a potentiometric sensor, tracking of ATR chemical and biological degradation kinetics can be performed in a very short time with excellent accuracy. The LOD was calculated to be 0.23 μmol L -1 , the potential drift was investigated over a period of 60 min and the value was 0.25 mV h -1 . Real serum samples for measurement the rate of in vitro metabolism of ATR was performed. Furthermore, a full description of the fabricated screen-printed sensor was presented. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. Next generation human skin constructs as advanced tools for drug development.

    Science.gov (United States)

    Abaci, H E; Guo, Zongyou; Doucet, Yanne; Jacków, Joanna; Christiano, Angela

    2017-11-01

    Many diseases, as well as side effects of drugs, manifest themselves through skin symptoms. Skin is a complex tissue that hosts various specialized cell types and performs many roles including physical barrier, immune and sensory functions. Therefore, modeling skin in vitro presents technical challenges for tissue engineering. Since the first attempts at engineering human epidermis in 1970s, there has been a growing interest in generating full-thickness skin constructs mimicking physiological functions by incorporating various skin components, such as vasculature and melanocytes for pigmentation. Development of biomimetic in vitro human skin models with these physiological functions provides a new tool for drug discovery, disease modeling, regenerative medicine and basic research for skin biology. This goal, however, has long been delayed by the limited availability of different cell types, the challenges in establishing co-culture conditions, and the ability to recapitulate the 3D anatomy of the skin. Recent breakthroughs in induced pluripotent stem cell (iPSC) technology and microfabrication techniques such as 3D-printing have allowed for building more reliable and complex in vitro skin models for pharmaceutical screening. In this review, we focus on the current developments and prevailing challenges in generating skin constructs with vasculature, skin appendages such as hair follicles, pigmentation, immune response, innervation, and hypodermis. Furthermore, we discuss the promising advances that iPSC technology offers in order to generate in vitro models of genetic skin diseases, such as epidermolysis bullosa and psoriasis. We also discuss how future integration of the next generation human skin constructs onto microfluidic platforms along with other tissues could revolutionize the early stages of drug development by creating reliable evaluation of patient-specific effects of pharmaceutical agents. Impact statement Skin is a complex tissue that hosts various

  3. Multivariate data analysis as a tool in advanced quality monitoring in the food production chain

    DEFF Research Database (Denmark)

    Bro, R.; van den Berg, F.; Thybo, A.

    2002-01-01

    This paper summarizes some recent advances in mathematical modeling of relevance in advanced quality monitoring in the food production chain. Using chemometrics-multivariate data analysis - it is illustrated how to tackle problems in food science more efficiently and, moreover, solve problems...

  4. THE ANALYSIS OF THE EVOLUTION OF THE FUNCTIONAL GEOMETRY OF THE TOOL AT THE LATHING WITH A TRANSVERSE ADVANCE

    Directory of Open Access Journals (Sweden)

    Dan DOBROTĂ

    2017-12-01

    Full Text Available The role of processing by machining is to generate surfaces that have to meet the requirements imposed by the designer through the execution drawing of the piece. The study aims to analyze how the functional geometry of the tool evolves when lathing with a transverse advance. The technological process of lathing with transverse advance is realized with a variable machining speed, and this also causes a variation of the functional geomtry of the tool. Thus, in the paper was established the optimal construction geometry of a lathe knife that can be used for lathing a piece of a certain diameter. Under these conditions, a correlation was established between the values of the geometrical constructive parameters of the knife used for the transverse lathing and the diameter of the workpiece which can be processed in optimal conditions

  5. Regional Innovation Clusters

    Data.gov (United States)

    Small Business Administration — The Regional Innovation Clusters serve a diverse group of sectors and geographies. Three of the initial pilot clusters, termed Advanced Defense Technology clusters,...

  6. Advances in Chimera Grid Tools for Multi-Body Dynamics Simulations and Script Creation

    Science.gov (United States)

    Chan, William M.

    2004-01-01

    This viewgraph presentation contains information about (1) Framework for multi-body dynamics - Geometry Manipulation Protocol (GMP), (2) Simulation procedure using Chimera Grid Tools (CGT) and OVERFLOW-2 (3) Further recent developments in Chimera Grid Tools OVERGRID, Grid modules, Script library and (4) Future work.

  7. Advancing Research in Second Language Writing through Computational Tools and Machine Learning Techniques: A Research Agenda

    Science.gov (United States)

    Crossley, Scott A.

    2013-01-01

    This paper provides an agenda for replication studies focusing on second language (L2) writing and the use of natural language processing (NLP) tools and machine learning algorithms. Specifically, it introduces a range of the available NLP tools and machine learning algorithms and demonstrates how these could be used to replicate seminal studies…

  8. Open innovation in urban energy systems

    Energy Technology Data Exchange (ETDEWEB)

    Arnold, M. [Technische Universitaet Muenchen, TUM School of Management, Freising (Germany); Barth, V. [Carl von Ossietzky Universitaet Oldenburg, Ecological Economics, Oldenburg (Germany)

    2012-08-15

    Despite recent efforts, existing urban energy systems still hardly meet the demands of sustainable development or climate change. Meeting these targets thus will require innovations that use energy much more efficiently and emit far less greenhouse gases. These innovations need to be made on the production as well as the consumption side, on all levels, and need to cover not only technical aspects, but even more service solutions. While many of these solutions still need to be developed, some are already invented but only exist in limited market segments. Opening closed urban planning processes and using open innovation tools can foster bottom-up urban energy system transformation by addressing the interactive ways of decision-making integrating company representatives and citizens. While open innovation tools like (open) innovation workshops or ideas competitions are already used by several companies to find and develop new designs and products, there is yet little experience with energy efficiency ideas and bottom-up changes. Therefore, we analyse energy-efficient ideas generated in three different ideas competitions. We discuss the findings for theory and research on open innovation approaches and bottom-up urban changes. Our results show that there are a vast number of ideas available in the public. Open innovation tools offer advanced possibilities to generate energy-efficient solutions.

  9. The role of advanced calculation and simulation tools in the evolution of fuel; El papel de las herramientas avanzadas de calculo y simulacion en la evolucion del combustible

    Energy Technology Data Exchange (ETDEWEB)

    Munoz-Reja, C.; Cerracin, A.; Corpa, R.

    2015-07-01

    This article is focused on the role of the advanced calculation/simulation tools on the development of the fuel designs as well as in the assessment of the effect of the changes in the operation. With this purpose, the article describes and shows some examples of the use by ENUSA of some of these tools in the fuel engineering. To conclude, the future on the evolution of the advanced tools is also presented. (Author)

  10. 3D scanning and printing as conversation tools: an innovative treatment of a vandalized bronze statue, The Thinker by Rodin

    NARCIS (Netherlands)

    Beentjes, T.; van der Molen, R.; Saunders, D.; Strlic, M.; Korenberg, C.; Luxford, N.; Birkhölzer, K.

    2013-01-01

    This contribution discusses the innovative treatment of a severely vandalized bronze sculpture, The Thinker by Auguste Rodin, from the Singer Museum in Laren, The Netherlands. Additional aspects of this controversial treatment such as decision making and documentation are also discussed. In 2007 the

  11. ADVANCED TOOLS FOR ASSESSING SELECTED PRESCRIPTION AND ILLICIT DRUGS IN TREATED SEWAGE EFFLUENTS AND SOURCE WATERS

    Science.gov (United States)

    The purpose of this poster is to present the application and assessment of advanced technologies in a real-world environment - wastewater effluent and source waters - for detecting six drugs (azithromycin, fluoxetine, omeprazole, levothyroxine, methamphetamine, and methylenedioxy...

  12. Biomimetic design method for innovation and sustainability

    CERN Document Server

    Helfman Cohen, Yael

    2017-01-01

    Presenting a novel biomimetic design method for transferring design solutions from nature to technology, this book focuses on structure-function patterns in nature and advanced modeling tools derived from TRIZ, the theory of inventive problem-solving. The book includes an extensive literature review on biomimicry as an engine of both innovation and sustainability, and discusses in detail the biomimetic design process, current biomimetic design methods and tools. The structural biomimetic design method for innovation and sustainability put forward in this text encompasses (1) the research method and rationale used to develop and validate this new design method; (2) the suggested design algorithm and tools including the Findstructure database, structure-function patterns and ideality patterns; and (3) analyses of four case studies describing how to use the proposed method. This book offers an essential resource for designers who wish to use nature as a source of inspiration and knowledge, innovators and sustain...

  13. Physics-based Modeling Tools for Life Prediction and Durability Assessment of Advanced Materials, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The technical objectives of this program are: (1) to develop a set of physics-based modeling tools to predict the initiation of hot corrosion and to address pit and...

  14. Evaluation and demonstration of commercialization potential of CCSI tools within gPROMS advanced simulation platform

    Energy Technology Data Exchange (ETDEWEB)

    Lawal, Adekola [Process Systems Enterprise Inc., Cedar Knolls, NJ (United States); Schmal, Pieter [Process Systems Enterprise Inc., Cedar Knolls, NJ (United States); Ramos, Alfredo [Process Systems Enterprise Inc., Cedar Knolls, NJ (United States); Cano, Alejandro [Process Systems Enterprise Inc., Cedar Knolls, NJ (United States); Bhattacharyya, Debangsu [West Virginia Univ., Morgantown, WV (United States); Mebane, David [West Virginia Univ., Morgantown, WV (United States); Sahinidis, Nikolaos [Carnegie Mellon Univ., Pittsburgh, PA (United States); Chowdhury, Ananya [Process Systems Enterprise Inc., Cedar Knolls, NJ (United States); Liu, Xiaohui [Process Systems Enterprise Inc., Cedar Knolls, NJ (United States); Bellinghausen, Stefan [Process Systems Enterprise Inc., Cedar Knolls, NJ (United States)

    2017-05-29

    PSE, in the first phase of the CCSI commercialization project, set out to identify market opportunities for the CCSI tools combined with existing gPROMS platform capabilities and develop a clear technical plan for the proposed commercialization activities.

  15. Advanced repair solution of clear defects on HTPSM by using nanomachining tool

    Science.gov (United States)

    Lee, Hyemi; Kim, Munsik; Jung, Hoyong; Kim, Sangpyo; Yim, Donggyu

    2015-10-01

    As the mask specifications become tighter for low k1 lithography, more aggressive repair accuracy is required below sub 20nm tech. node. To meet tight defect specifications, many maskshops select effective repair tools according to defect types. Normally, pattern defects are repaired by the e-beam repair tool and soft defects such as particles are repaired by the nanomachining tool. It is difficult for an e-beam repair tool to remove particle defects because it uses chemical reaction between gas and electron, and a nanomachining tool, which uses physical reaction between a nano-tip and defects, cannot be applied for repairing clear defects. Generally, film deposition process is widely used for repairing clear defects. However, the deposited film has weak cleaning durability, so it is easily removed by accumulated cleaning process. Although the deposited film is strongly attached on MoSiN(or Qz) film, the adhesive strength between deposited Cr film and MoSiN(or Qz) film becomes weaker and weaker by the accumulated energy when masks are exposed in a scanner tool due to the different coefficient of thermal expansion of each materials. Therefore, whenever a re-pellicle process is needed to a mask, all deposited repair points have to be confirmed whether those deposition film are damaged or not. And if a deposition point is damaged, repair process is needed again. This process causes longer and more complex process. In this paper, the basic theory and the principle are introduced to recover clear defects by using nanomachining tool, and the evaluated results are reviewed at dense line (L/S) patterns and contact hole (C/H) patterns. Also, the results using a nanomachining were compared with those using an e-beam repair tool, including the cleaning durability evaluated by the accumulated cleaning process. Besides, we discuss the phase shift issue and the solution about the image placement error caused by phase error.

  16. Proposal for a Method for Business Model Performance Assessment: Toward an Experimentation Tool for Business Model Innovation

    Directory of Open Access Journals (Sweden)

    Antonio Batocchio

    2017-04-01

    Full Text Available The representation of business models has been recently widespread, especially in the pursuit of innovation. However, defining a company’s business model is sometimes limited to discussion and debates. This study observes the need for performance measurement so that business models can be data-driven. To meet this goal, the work proposed as a hypothesis the creation of a method that combines the practices of the Balanced Scorecard with a method of business models representation – the Business Model Canvas. Such a combination was based on study of conceptual adaptation, resulting in an application roadmap. A case study application was performed to check the functionality of the proposition, focusing on startup organizations. It was concluded that based on the performance assessment of the business model it is possible to propose the search for change through experimentation, a path that can lead to business model innovation.

  17. Functional connectivity in post-stroke aphasia: innovative tools at the service of evidence-based practice

    Directory of Open Access Journals (Sweden)

    Edith Durand

    2014-05-01

    This study presents an innovative approach to clinical management in post-stroke aphasia. Specifically, the evidence shows that specific anomia therapy for verbs normalizes DMN integration, thus reflecting the large scope impact of speech therapy. Also, the correlation between DMN integration values and reactivity to SFA/V shows that DMN status before therapy can be predictive of response to specific therapy. Altogether, these results show that functional integration measures of the DMN can highlight prognosis and therapy efficiency in aphasia rehabilitation.

  18. Implementation of a professional portfolio: a tool to demonstrate professional development for advanced practice.

    Science.gov (United States)

    Chamblee, Tracy B; Dale, Juanita Conkin; Drews, Barbie; Spahis, Joanna; Hardin, Teri

    2015-01-01

    The literature has a gap related to professional development for APRNs. In the United States, many health care organizations use clinical advancement programs for registered nurses, but APRNs are not often included in these programs. If APRNs are included, advancement opportunities are very limited. At CMC, implementation of a professional portfolio resulted in increased satisfaction among APPs regarding their ability to showcase professional growth and expertise, as well as the uniqueness of their advanced practice. Use of the professional portfolio led to improved recognition by APS and organizational leaders of APP performance excellence during the annual performance evaluation, as well as improved recognition among APP colleagues in terms of nominations for honors and awards.

  19. Diffusion Weighted MRI as a predictive tool for effect of radiotherapy in locally advanced cervical cancer

    DEFF Research Database (Denmark)

    Haack, Søren; Tanderup, Kari; Fokdal, Lars

    Diffusion weighted MRI has shown great potential in diagnostic cancer imaging and may also have value for monitoring tumor response during radiotherapy. Patients with advanced cervical cancer are treated with external beam radiotherapy followed by brachytherapy. This study evaluates the value of DW......-MRI for predicting outcome of patients with advanced cervical cancer at time of brachytherapy. Volume of hyper-intensity on highly diffusion sensitive images and resulting ADC value for treatment responders and non-responders is compared. The change of ADC and volume of hyper-intensity over time of BT is also...

  20. THE PROJECTED RATE OF COMPETENCE FORMATION AS A TOOL OF EDUCATIONAL MANAGEMENT OF ADVANCED LEVEL OF EDUCATION

    Directory of Open Access Journals (Sweden)

    L. V. Lvov

    2017-01-01

    Full Text Available Introduction. Specially organized complex of the scientific research directed to obtaining the reliable advancing information about development of pedagogical members is necessary for the development of educational policy, the strategy of development for educational systems, and methods of management of quality of pedagogical activity at different stages of education. The result of the educational management of professional and educational process is caused by the quality of pedagogical design. In turn, the quality of pedagogical forecasting is a factor determining the overall effectiveness of management through the pedagogical design.The aim of this article is to describe the model that allows applying the rate of competence formation as a tool of educational management and providing the advanced level of education. Methodology and research methods are based on pre-competence and context approach, which supposes the content selection as a set of competencies and designing the educational and professional process with the use of the rate of formation of ability and readiness (competency as a tool of teaching management.Results. The author states socio-pedagogical contradiction, which is in acute shortage of predictive tools in the management of the educational process. The article describes terminology and empirical mathematical models that underpin pedagogical management of the educational and professional training of students that provides the advanced level of formation of organizational and managerial competence.Scientific novelty. The author clarifies the concept of the advanced level of education; introduces the term of the rate of formation of competency; proposes a new model to solve the problem of predicting learning outcomes and timely management influence by managers of education at all stages of the design and functioning of the educational system in the conditions of implementation of competence-based approach in the higher school

  1. Cluster as a Tool to Increase the Competitiveness and Innovative Activity of Enterprises of the Defense Industry Complex

    Directory of Open Access Journals (Sweden)

    Katrina B. Dobrova

    2017-01-01

    Full Text Available Purpose: the main goal of the publication is to make a comprehensive study of the possible application of the cluster approach to improve the competitiveness and innovation activity of enterprises of the defense industry complex.Methods: the methodology of the research is based on the collection and analysis of initial data and information, the article uses a systematic approach to the study of socio-economic processes and phenomena. The research is based on modern theory of competition, innovation, as well as the modern paradigm of cluster development of the economy. In preparing the study, practical materials from Corporation “Rostec”.Results: the article gives the notion of cluster, the prospects for the use of the cluster approach to enhance competitiveness and innovation enterprises of the military-industrial complex. It is noted that the activation of interaction with the “civil sector” is particularly relevant in the context of the reduction of the state defense order, and the theory and practice of cluster management offers a number of forms of cluster interaction between the enterprises of the defense industry and the civil sector. It is emphasized that the development of cluster mechanisms can solve a number of problems related to the insufficient financial stability of defense industry enterprises in the context of a reduction in the state defense order, low innovation activity and the lack of developed models of interaction with small innovative enterprises. Ultimately, the use of cluster mechanisms in the development of defense enterprises is intended to enhance the competitiveness of the complex, both nationally and globally. It is stated that the existing clusters are not able to fully solve a number of specific tasks related to the diversification of integrated defense industry structures. Attention is drawn to the fact that existing clusters are not able to fully solve a number of specific tasks related to the

  2. Energy systems. Tome 3: advanced cycles, low environmental impact innovative systems; Systeme energetiques, TOME 3: cycles avances, systemes innovants a faible impact environnemental

    Energy Technology Data Exchange (ETDEWEB)

    Gicquel, R

    2009-07-01

    This third tome about energy systems completes the two previous ones by showing up advanced thermodynamical cycles, in particular having a low environmental impact, and by dealing with two other questions linked with the study of systems with a changing regime operation: - the time management of energy, with the use of thermal and pneumatic storage systems and time simulation (schedule for instance) of systems (solar energy type in particular); - the technological dimensioning and non-nominal regime operation studies. Because this last topic is particularly complex, new functionalities have been implemented mainly by using the external classes mechanism, which allows the user to freely personalize his models. This tome is illustrated with about 50 examples of cycles modelled with Thermoptim software. Content: foreword; 1 - generic external classes; 2 - advanced gas turbine cycles; 3 - evaporation-concentration, mechanical steam compression, desalination, hot gas drying; 4 - cryogenic cycles; 5 - electrochemical converters; 6 - global warming, CO{sub 2} capture and sequestration; 7 - future nuclear reactors (coupled to Hirn and Brayton cycles); 8 - thermodynamic solar cycles; 10 - pneumatic and thermal storage; 11 - calculation of thermodynamic solar facilities; 12 - problem of technological dimensioning and non-nominal regime; 13 - exchangers modeling and parameterizing for the dimensioning and the non-nominal regime; 14 - modeling and parameterizing of volumetric compressors; 15 - modeling and parameterizing of turbo-compressors and turbines; 16 - identification methodology of component parameters; 17 - case studies. (J.S.)

  3. Research, development and innovation in the electrical energy sector of Brazil: toward a tool for the support of the decision-making process

    Energy Technology Data Exchange (ETDEWEB)

    Machado, Fernando Vieira; Salles-Filho, Sergio; Brittes, Jose Juiz Pereira; Corder, Solange Maria; Boer, Denile Cominato [Universidade Estadual de Campinas (UNICAMP), SP (Brazil)

    2008-07-01

    The objective of this article is to present a tool to help in the decision making process for the allocation of resources for research, development and innovation in the electrical energy sector in Brazil. It provides a computerized tool for the management of a portfolio of projects which contains myriads of information of projects of research, development, and innovation financed by companies in the area of the generation, transmission and distribution of electrical energy in Brazil. This tool permits the collection and analysis of this information with a view to evaluating the direction and progress of investments made in the past five years. The electrical energy sector of Brazil invests hundreds of millions of reals each year in research and development (henceforth 'R and D'). The investment of these resources is required by a set of federal laws. This legal framework is a consequence of the process of the privatization of the sector which began in 1997. The investment of the financial resources in R and D projects is supervised by the Brazilian Electricity Regulatory Agency (henceforth 'ANEEL'). It is the responsibility of ANEEL to evaluate and approve proposed R and D projects, and monitor their results, as per the 'Handbook of R and D of the Electrical Energy Sector.' This tool for supporting the decision-making process serves exactly the purpose of helping both ANEEL in the approval of resources under its supervision, as well as helping companies within the electrical energy sector in the management of applied resources. Almost one billion reals (approximately US $500,000,000) were invested in more than 3000 projects from 1998 to 2006. The data base associated with these projects already contains information concerning 1412 projects from 1998 to 2004, permitting significant analyses of the results and impacts of the allocation of resources. (author)

  4. Teaching Advanced Concepts in Computer Networks: VNUML-UM Virtualization Tool

    Science.gov (United States)

    Ruiz-Martinez, A.; Pereniguez-Garcia, F.; Marin-Lopez, R.; Ruiz-Martinez, P. M.; Skarmeta-Gomez, A. F.

    2013-01-01

    In the teaching of computer networks the main problem that arises is the high price and limited number of network devices the students can work with in the laboratories. Nowadays, with virtualization we can overcome this limitation. In this paper, we present a methodology that allows students to learn advanced computer network concepts through…

  5. Just-in-Time Teaching: A Tool for Enhancing Student Engagement in Advanced Foreign Language Learning

    Science.gov (United States)

    Abreu, Laurel; Knouse, Stephanie

    2014-01-01

    Scholars have indicated a need for further research on effective pedagogical strategies designed for advanced foreign language courses in the postsecondary setting, especially in light of decreased enrollments at this level and the elimination of foreign language programs altogether in some institutions (Paesani & Allen, 2012). This article…

  6. A Clinical Assessment Tool for Advanced Theory of Mind Performance in 5 to 12 Year Olds

    Science.gov (United States)

    O'Hare, Anne E.; Bremner, Lynne; Nash, Marysia; Happe, Francesca; Pettigrew, Luisa M.

    2009-01-01

    One hundred forty typically developing 5- to 12-year-old children were assessed with a test of advanced theory of mind employing Happe's strange stories. There was no significant difference in performance between boys and girls. The stories discriminated performance across the different ages with the lowest performance being in the younger…

  7. Advanced tools for modeling, design and optimization of wind turbine systems

    DEFF Research Database (Denmark)

    Iov, F.; Hansen, A.D.; Jauch, C.

    2005-01-01

    As wind turbine technology and control has advanced over the last decade, this has led to a high penetration of wind turbines into the power system. Whether it be for a large wind turbine or an offshore wind farm with hundreds of MW power capacity, the electrical system has become more and more i...

  8. Social Capital and Entrepreneurial Behaviour Advancing Innovativeness in Interaction between Small Rural Entrepreneurs and Researchers: A Phenomenographic Study

    Science.gov (United States)

    Iivonen, Sari; Kyro, Paula; Mynttinen, Sinikka; Sarkka-Tirkkonen, Marjo; Kahiluoto, Helena

    2011-01-01

    Innovation processes between entrepreneurs and researchers are activated by interaction. Social capital increases the efficiency of action, for example, information dissemination by minimising redundancy. To learn more about how to build and develop social capital assumes that we understand how entrepreneurs behave and what their expectations of…

  9. Innovating innovation Policy. Rethinking green innovation policy in evolutionary perspective

    NARCIS (Netherlands)

    Arentsen, Maarten J.; Dinica, V.; Marquart, N.E.

    1999-01-01

    Advanced environmental standards such as sustainability require substantial improvements in the environmental performances of present technologies. Governments are faced with the challenge to design green innovation policies able to support producers and users of technologies to comply with such

  10. Innovation in Retail Process: From Consumers’ Experience to Immersive Store Design

    Directory of Open Access Journals (Sweden)

    Eleonora Pantano

    2012-09-01

    Full Text Available Due to the current advances in Information and Communication Technologies and consumers’ increasing interest in entertaining and interactive retail environments, the sector of retailing is forced to pursuit innovation to maintain existing consumers and attract new ones. Especially the use of virtual reality techniques offers tools for supporting the design of innovative systems capable of enhancing this process. The aim of this paper is to integrate the consumers’ experience in the development of innovation process for retailing. In particular, our findings highlight how the immersive technologies can be an efficient tool for pushing innovation in retailing. Therefore, the paper provides important issues for scholars and practitioners.

  11. The development of environmental assessment tools to support the creation of dementia friendly care environments: Innovative practice.

    Science.gov (United States)

    Waller, Sarah; Masterson, Abigail; Evans, Simon C

    2017-02-01

    The need for more dementia friendly design in hospitals and other care settings is now widely acknowledged. Working with 26 NHS Trusts in England as part of a Department of Health commissioned programme, The King's Fund developed a set of overarching design principles and an environmental assessment tool for hospital wards in 2012. Following requests from other sectors, additional tools were developed for hospitals, care homes, health centres and housing with care. The tools have proven to be effective in both disseminating the principles of dementia friendly design and in enabling the case to be made for improvements that have a positive effect on patient outcomes and staff morale. This paper reports on the development, use and review of the environmental assessment tools, including further work that is now being taken forward by The Association for Dementia Studies, University of Worcester.

  12. Development of a Screening Tool to Facilitate Technology Transfer of an Innovative Technology to Treat Perchlorate-Contaminated Water

    National Research Council Canada - National Science Library

    Craig, Daniel A

    2008-01-01

    Perchlorate contamination of drinking water is a significant problem nationwide. The purpose of this study was to develop a tool to predict the cost and performance of tailored granular activated carbon (T-GAC...

  13. Effects of advanced laser processing on the microstructure and residual stresses of H13 tool steel

    NARCIS (Netherlands)

    Trojan, Karel; Ocelík, Václav; Ganev, Nikolaj; Němeček, Stanislav; Čapek, Jiří

    2017-01-01

    The aim of this paper is to describe the effects of laser processing on the microstructure and residual stresses of laser cladded H13 tool steel on the classical construct steel S355 substrate. This research paper concludes that in this case of laser cladding, phase transformation and not shrinkage

  14. Optimization of Friction Stir Welding Tool Advance Speed via Monte-Carlo Simulation of the Friction Stir Welding Process.

    Science.gov (United States)

    Fraser, Kirk A; St-Georges, Lyne; Kiss, Laszlo I

    2014-04-30

    Recognition of the friction stir welding process is growing in the aeronautical and aero-space industries. To make the process more available to the structural fabrication industry (buildings and bridges), being able to model the process to determine the highest speed of advance possible that will not cause unwanted welding defects is desirable. A numerical solution to the transient two-dimensional heat diffusion equation for the friction stir welding process is presented. A non-linear heat generation term based on an arbitrary piecewise linear model of friction as a function of temperature is used. The solution is used to solve for the temperature distribution in the Al 6061-T6 work pieces. The finite difference solution of the non-linear problem is used to perform a Monte-Carlo simulation (MCS). A polynomial response surface (maximum welding temperature as a function of advancing and rotational speed) is constructed from the MCS results. The response surface is used to determine the optimum tool speed of advance and rotational speed. The exterior penalty method is used to find the highest speed of advance and the associated rotational speed of the tool for the FSW process considered. We show that good agreement with experimental optimization work is possible with this simplified model. Using our approach an optimal weld pitch of 0.52 mm/rev is obtained for 3.18 mm thick AA6061-T6 plate. Our method provides an estimate of the optimal welding parameters in less than 30 min of calculation time.

  15. LACO-Wiki: A land cover validation tool and a new, innovative teaching resource for remote sensing and the geosciences

    Science.gov (United States)

    See, Linda; Perger, Christoph; Dresel, Christopher; Hofer, Martin; Weichselbaum, Juergen; Mondel, Thomas; Steffen, Fritz

    2016-04-01

    The validation of land cover products is an important step in the workflow of generating a land cover map from remotely-sensed imagery. Many students of remote sensing will be given exercises on classifying a land cover map followed by the validation process. Many algorithms exist for classification, embedded within proprietary image processing software or increasingly as open source tools. However, there is little standardization for land cover validation, nor a set of open tools available for implementing this process. The LACO-Wiki tool was developed as a way of filling this gap, bringing together standardized land cover validation methods and workflows into a single portal. This includes the storage and management of land cover maps and validation data; step-by-step instructions to guide users through the validation process; sound sampling designs; an easy-to-use environment for validation sample interpretation; and the generation of accuracy reports based on the validation process. The tool was developed for a range of users including producers of land cover maps, researchers, teachers and students. The use of such a tool could be embedded within the curriculum of remote sensing courses at a university level but is simple enough for use by students aged 13-18. A beta version of the tool is available for testing at: http://www.laco-wiki.net.

  16. Recent advances in microbial production of fuels and chemicals using tools and strategies of systems metabolic engineering

    DEFF Research Database (Denmark)

    Cho, Changhee; Choi, So Young; Luo, Zi Wei

    2015-01-01

    The advent of various systems metabolic engineering tools and strategies has enabled more sophisticated engineering of microorganisms for the production of industrially useful fuels and chemicals. Advances in systems metabolic engineering have been made in overproducing natural chemicals...... and producing novel non-natural chemicals. In this paper, we review the tools and strategies of systems metabolic engineering employed for the development of microorganisms for the production of various industrially useful chemicals belonging to fuels, building block chemicals, and specialty chemicals......, in particular focusing on those reported in the last three years. It was aimed at providing the current landscape of systems metabolic engineering and suggesting directions to address future challenges towards successfully establishing processes for the bio-based production of fuels and chemicals from renewable...

  17. Recent advances in microbial production of fuels and chemicals using tools and strategies of systems metabolic engineering.

    Science.gov (United States)

    Cho, Changhee; Choi, So Young; Luo, Zi Wei; Lee, Sang Yup

    2015-11-15

    The advent of various systems metabolic engineering tools and strategies has enabled more sophisticated engineering of microorganisms for the production of industrially useful fuels and chemicals. Advances in systems metabolic engineering have been made in overproducing natural chemicals and producing novel non-natural chemicals. In this paper, we review the tools and strategies of systems metabolic engineering employed for the development of microorganisms for the production of various industrially useful chemicals belonging to fuels, building block chemicals, and specialty chemicals, in particular focusing on those reported in the last three years. It was aimed at providing the current landscape of systems metabolic engineering and suggesting directions to address future challenges towards successfully establishing processes for the bio-based production of fuels and chemicals from renewable resources. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Innovation at DARPA

    Science.gov (United States)

    2016-07-01

    Distribution Statement A: Approved for Public Release, Distribution Unlimited Innovation at DARPA July 2016 1 Distribution...Statement A: Approved for Public Release, Distribution Unlimited Innovation at DARPA A Long History of Innovation DARPA, the Defense Advanced Research...guided work that has “changed the world"—a phrase frequently heard at DARPA to ensure a focus on transformative innovation as opposed to incremental

  19. Potential for MERLIN-Expo, an advanced tool for higher tier exposure assessment, within the EU chemical legislative frameworks

    International Nuclear Information System (INIS)

    Suciu, Nicoleta; Tediosi, Alice; Ciffroy, Philippe; Altenpohl, Annette; Brochot, Céline; Verdonck, Frederik; Ferrari, Federico; Giubilato, Elisa; Capri, Ettore; Fait, Gabriella

    2016-01-01

    MERLIN-Expo merges and integrates advanced exposure assessment methodologies, allowing the building of complex scenarios involving several pollution sources and targets. The assessment of exposure and risks to human health from chemicals is of major concern for policy and ultimately benefits all citizens. The development and operational fusion of the advanced exposure assessment methodologies envisaged in the MERLIN-Expo tool will have a significant impact in the long term on several policies dealing with chemical safety management. There are more than 30 agencies in Europe related to exposure and risk evaluation of chemicals, which have an important role in implementing EU policies, having especially tasks of technical, scientific, operational and/or regulatory nature. The main purpose of the present paper is to introduce MERLIN-Expo and to highlight its potential for being effectively integrated within the group of tools available to assess the risk and exposure of chemicals for EU policy. The main results show that the tool is highly suitable for use in site-specific or local impact assessment, with minor modifications it can also be used for Plant Protection Products (PPPs), biocides and REACH, while major additions would be required for a comprehensive application in the field of consumer and worker exposure assessment. - Highlights: • Exposure and risk evaluation of chemicals • Coupling environmental exposure and pharmacokinetic models • MERLIN-expo as a higher tier exposure tool • MERLIN-expo potential application in EU chemical regulations • EU legislations and policies related to risk assessment and management of chemicals

  20. Potential for MERLIN-Expo, an advanced tool for higher tier exposure assessment, within the EU chemical legislative frameworks

    Energy Technology Data Exchange (ETDEWEB)

    Suciu, Nicoleta, E-mail: nicoleta.suciu@unicatt.it [Università Cattolica del Sacro Cuore, 29122 Piacenza (Italy); Tediosi, Alice [Aeiforia Srl, 29027 Gariga di Podenzano (PC) (Italy); Ciffroy, Philippe [Electricité de France (EDF) R& D, National Hydraulic and Environment Laboratory, 6 quai Watier, 78400 Chatou (France); Altenpohl, Annette [Österreichisches Normungsinstitut/Austrian Standards Institute, Heinestraße 38, 1020 Wien (Austria); Brochot, Céline [INERIS, Parc ALATA, BP2, 60550 Verneuil en Halatte (France); Verdonck, Frederik [ARCHE cvba, Liefkensstraat 35d, 9032 Gent-Wondelgem (Belgium); Ferrari, Federico [Aeiforia Srl, 29027 Gariga di Podenzano (PC) (Italy); Giubilato, Elisa [University Ca Foscari Venice, Department of Environmental Sciences, Informatics and Statistics, via Torino 155, 30172 Mestre-Venice (Italy); Capri, Ettore [Università Cattolica del Sacro Cuore, 29122 Piacenza (Italy); Fait, Gabriella [EFSA, via Carlo Magno 1/a, 43126 Parma (Italy)

    2016-08-15

    MERLIN-Expo merges and integrates advanced exposure assessment methodologies, allowing the building of complex scenarios involving several pollution sources and targets. The assessment of exposure and risks to human health from chemicals is of major concern for policy and ultimately benefits all citizens. The development and operational fusion of the advanced exposure assessment methodologies envisaged in the MERLIN-Expo tool will have a significant impact in the long term on several policies dealing with chemical safety management. There are more than 30 agencies in Europe related to exposure and risk evaluation of chemicals, which have an important role in implementing EU policies, having especially tasks of technical, scientific, operational and/or regulatory nature. The main purpose of the present paper is to introduce MERLIN-Expo and to highlight its potential for being effectively integrated within the group of tools available to assess the risk and exposure of chemicals for EU policy. The main results show that the tool is highly suitable for use in site-specific or local impact assessment, with minor modifications it can also be used for Plant Protection Products (PPPs), biocides and REACH, while major additions would be required for a comprehensive application in the field of consumer and worker exposure assessment. - Highlights: • Exposure and risk evaluation of chemicals • Coupling environmental exposure and pharmacokinetic models • MERLIN-expo as a higher tier exposure tool • MERLIN-expo potential application in EU chemical regulations • EU legislations and policies related to risk assessment and management of chemicals.

  1. Using Enabling Technologies to Advance Data Intensive Analysis Tools in the JPL Tropical Cyclone Information System

    Science.gov (United States)

    Knosp, B.; Gangl, M. E.; Hristova-Veleva, S. M.; Kim, R. M.; Lambrigtsen, B.; Li, P.; Niamsuwan, N.; Shen, T. P. J.; Turk, F. J.; Vu, Q. A.

    2014-12-01

    The JPL Tropical Cyclone Information System (TCIS) brings together satellite, aircraft, and model forecast data from several NASA, NOAA, and other data centers to assist researchers in comparing and analyzing data related to tropical cyclones. The TCIS has been supporting specific science field campaigns, such as the Genesis and Rapid Intensification Processes (GRIP) campaign and the Hurricane and Severe Storm Sentinel (HS3) campaign, by creating near real-time (NRT) data visualization portals. These portals are intended to assist in mission planning, enhance the understanding of current physical processes, and improve model data by comparing it to satellite and aircraft observations. The TCIS NRT portals allow the user to view plots on a Google Earth interface. To compliment these visualizations, the team has been working on developing data analysis tools to let the user actively interrogate areas of Level 2 swath and two-dimensional plots they see on their screen. As expected, these observation and model data are quite voluminous and bottlenecks in the system architecture can occur when the databases try to run geospatial searches for data files that need to be read by the tools. To improve the responsiveness of the data analysis tools, the TCIS team has been conducting studies on how to best store Level 2 swath footprints and run sub-second geospatial searches to discover data. The first objective was to improve the sampling accuracy of the footprints being stored in the TCIS database by comparing the Java-based NASA PO.DAAC Level 2 Swath Generator with a TCIS Python swath generator. The second objective was to compare the performance of four database implementations - MySQL, MySQL+Solr, MongoDB, and PostgreSQL - to see which database management system would yield the best geospatial query and storage performance. The final objective was to integrate our chosen technologies with our Joint Probability Density Function (Joint PDF), Wave Number Analysis, and

  2. [Most innovative drugs labelled during the last years in paediatrics: does the paediatrician have the tools for their identification?].

    Science.gov (United States)

    Autret-Leca, E

    2010-08-01

    When a new drug is labelled, before deciding its integration in the therapeutic strategy, the doctor has to know the degree of innovation of the drug, i.e. its actual benefit and the improvement of actual benefit, also called added value over other available drugs. For each new medicine in France, after drug approval by the French Drug Agency, the French National Authority for Health thought its "Commission de transparence" (Transparency Commission) issues an opinion about the degree of innovation of the drug, which is independent of the marketing authorization. The added value over other available drugs is quantified by five levels of improvement: level I, major progress to level V, no progress. The complete opinion of the Transparency Commission and its synthesis (one page) is online http://www.has-sante.fr/. Between 2006 and 2008, no paediatric drug has obtained a level I of improvement (major progress), ten have obtained a level II (significant progress), 11 a level III (moderate progress), 12 a level IV (minor progress) and for 38 drugs, no progress has been retained. The need to know and to follow therapeutic recommendations is the evidence based medicine. The opinions of the Transparency Commission are one of those recommendations. Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.

  3. EEGLAB, SIFT, NFT, BCILAB, and ERICA: new tools for advanced EEG processing.

    Science.gov (United States)

    Delorme, Arnaud; Mullen, Tim; Kothe, Christian; Akalin Acar, Zeynep; Bigdely-Shamlo, Nima; Vankov, Andrey; Makeig, Scott

    2011-01-01

    We describe a set of complementary EEG data collection and processing tools recently developed at the Swartz Center for Computational Neuroscience (SCCN) that connect to and extend the EEGLAB software environment, a freely available and readily extensible processing environment running under Matlab. The new tools include (1) a new and flexible EEGLAB STUDY design facility for framing and performing statistical analyses on data from multiple subjects; (2) a neuroelectromagnetic forward head modeling toolbox (NFT) for building realistic electrical head models from available data; (3) a source information flow toolbox (SIFT) for modeling ongoing or event-related effective connectivity between cortical areas; (4) a BCILAB toolbox for building online brain-computer interface (BCI) models from available data, and (5) an experimental real-time interactive control and analysis (ERICA) environment for real-time production and coordination of interactive, multimodal experiments.

  4. [Biomarkers in emergency medicine and critical care patients: advances and pitfalls for news tools].

    Science.gov (United States)

    Claessens, Yann-Erick; Mallet-Coste, Thomas; Riqué, Thomas; Macchi, Marc-Alexis; Ray, Patrick; Chenevier-Gobeaux, Camille

    2014-01-01

    The use of biomarkers has changed approach of diagnosis and treatment procedures in emergency medicine, especially in the field of cardiovascular disorders. Effectiveness of new strategies that integrate biomarkers has precluded development and research in novel tools that may improve safety and efficiency at bedside. This mini-review presents current knowledge on utility of biomarkers in emergency medicine, including data that should be taken into account to avoid misleading utilization. Copyright © 2013. Published by Elsevier Masson SAS.

  5. Effects of advanced laser processing on the microstructure and residual stresses of H13 tool steel

    OpenAIRE

    Trojan, Karel; Ocelík, Václav; Ganev, Nikolaj; Němeček, Stanislav; Čapek, Jiří

    2017-01-01

    The aim of this paper is to describe the effects of laser processing on the microstructure and residual stresses of laser cladded H13 tool steel on the classical construct steel S355 substrate. This research paper concludes that in this case of laser cladding, phase transformation and not shrinkage is likely to be a dominant effect on the formation of compressive residual stresses along the clad. Furthermore, martensitic structure and unequal concentration of alloying elements was observed on...

  6. Advanced software tool for the creation of a typical meteorological year

    International Nuclear Information System (INIS)

    Skeiker, Kamal; Ghani, Bashar Abdul

    2008-01-01

    The generation of a typical meteorological year is of great importance for calculations concerning many applications in the field of thermal engineering. In this context, method that has been proposed by Hall et al. is selected for generating typical data, and an improved criterion for final selection of typical meteorological month (TMM) was demonstrated. The final selection of the most representative year was done by examining a composite score S. The composite score was calculated as the weighed sum of the scores of the four meteorological parameters used. These parameters are air dry bulb temperature, relative humidity, wind velocity and global solar radiation intensity. Moreover, a new modern software tool using Delphi 6.0 has been developed, utilizing the Filkenstein-Schafer statistical method for the creation of a typical meteorological year for any site of concern. Whereas, an improved criterion for final selection of typical meteorological month was employed. Such tool allows the user to perform this task without an intimate knowledge of all of the computational details. The final alphanumerical and graphical results are presented on screen, and can be saved to a file or printed as a hard copy. Using this software tool, a typical meteorological year was generated for Damascus, capital of Syria, as a test run example. The data processed used were obtained from the Department of Meteorology and cover a period of 10 years (1991-2000)

  7. Advanced Neutron Detection Methods: new Tools for Countering Nuclear Terrorism (412th Brookhaven Lecture)

    International Nuclear Information System (INIS)

    Vanier, Peter

    2006-01-01

    Acts of terrorism have become almost daily occurrences in the international news. Yet one of the most feared types of terrorism - nuclear terrorism - has not yet happened. One important way of preventing nuclear terrorism is to safeguard nuclear materials, and many people worldwide work continuously to achieve that goal. A second, vital defense is being developed: greatly improved methods of detecting material that a nuclear terrorist would need so that timely discovery of the material could become more probable. Special nuclear materials can emit neutrons, either spontaneously or when excited by a source of high-energy gamma rays, such as an electron accelerator. Traditional neutron detectors can sense these neutrons, but not the direction from which the neutrons come, or their energy. The odds against finding smuggled nuclear materials using conventional detectors are great. However, innovative designs of detectors are producing images that show the locations and even the shapes of man-made neutron sources, which stand out against the uniform background produced by cosmic rays. With the new detectors, finding needles in haystacks - or smuggled nuclear materials in a huge container among thousands of others in a busy port - suddenly becomes possible.

  8. The Advanced Light Source: A new tool for research in atomic and molecular physics

    International Nuclear Information System (INIS)

    Schlachter, F.; Robinson, A.

    1991-04-01

    The Advanced Light Source at the Lawrence Berkeley Laboratory will be the world's brightest synchrotron radiation source in the extreme ultraviolet and soft x-ray regions of the spectrum when it begins operation in 1993. It will be available as a national user facility to researchers in a broad range of disciplines, including materials science, atomic and molecular physics, chemistry, biology, imaging, and technology. The high brightness of the ALS will be particularly well suited to high-resolution studies of tenuous targets, such as excited atoms, ions, and clusters. 13 figs., 4 tabs

  9. The lead-acid eloflux cell. Research tool and candidate for advanced batteries

    Energy Technology Data Exchange (ETDEWEB)

    Kullmeine, U.; Kappus, W.

    1982-12-01

    The discharge capacity of usual lead-acid cells is limited by several mechanisms among which acid depletion is the most incisive. It is shown that the use of the so-called eloflux principle which is characterized by the flow of electrolyte through the porous electrodes, allows a significant deepe discharge and that by avoiding acid depletion the study of the other limiting processes and their functional dependence on the discharge conditions is possible. From the results it is concluded that an eloflux lead-acid cell is a promising candidate for advanced batteries with high energy density and performance.

  10. Performance analysis and optimization of an advanced pharmaceutical wastewater treatment plant through a visual basic software tool (PWWT.VB).

    Science.gov (United States)

    Pal, Parimal; Thakura, Ritwik; Chakrabortty, Sankha

    2016-05-01

    A user-friendly, menu-driven simulation software tool has been developed for the first time to optimize and analyze the system performance of an advanced continuous membrane-integrated pharmaceutical wastewater treatment plant. The software allows pre-analysis and manipulation of input data which helps in optimization and shows the software performance visually on a graphical platform. Moreover, the software helps the user to "visualize" the effects of the operating parameters through its model-predicted output profiles. The software is based on a dynamic mathematical model, developed for a systematically integrated forward osmosis-nanofiltration process for removal of toxic organic compounds from pharmaceutical wastewater. The model-predicted values have been observed to corroborate well with the extensive experimental investigations which were found to be consistent under varying operating conditions like operating pressure, operating flow rate, and draw solute concentration. Low values of the relative error (RE = 0.09) and high values of Willmott-d-index (d will = 0.981) reflected a high degree of accuracy and reliability of the software. This software is likely to be a very efficient tool for system design or simulation of an advanced membrane-integrated treatment plant for hazardous wastewater.

  11. Frugal innovation in medicine for low resource settings.

    Science.gov (United States)

    Tran, Viet-Thi; Ravaud, Philippe

    2016-07-07

    Whilst it is clear that technology is crucial to advance healthcare: innovation in medicine is not just about high-tech tools, new procedures or genome discoveries. In constrained environments, healthcare providers often create unexpected solutions to provide adequate healthcare to patients. These inexpensive but effective frugal innovations may be imperfect, but they have the power to ensure that health is within reach of everyone. Frugal innovations are not limited to low-resource settings: ingenuous ideas can be adapted to offer simpler and disruptive alternatives to usual care all around the world, representing the concept of "reverse innovation". In this article, we discuss the different types of frugal innovations, illustrated with examples from the literature, and argue for the need to give voice to this neglected type of innovation in medicine.

  12. Development of advanced risk informed asset management tool based on system dynamics approach for nuclear power plant

    International Nuclear Information System (INIS)

    Lee, Gyoung Cheol

    2007-02-01

    In the competitive circumstance of electricity industry, the economic efficiency of electricity generation facility is the most important factor to increase their competitiveness. For nuclear power plant (NPP), safety is also an essential factor. Over fast several years, efforts for development of safety concerned and financial asset maximizing method, process and tools have been continued internationally and Risk-Informed Asset Management (RIAM) methodology is suggested by Electric Power Research Institute (EPRI). This RIAM methodology is expected to provide plant operators with a project prioritization and life cycle management planning tool for making long-term maintenance plans, guiding plant budgeting, and determining the sensitivity of a plant's economic risk to the reliability and availability of system, structure, and components (SSC), as well as other technical and economic parameters. The focus of this study is to develop model that help us to resource allocation, to find what effect such allocations on the plant economic and safety performance. Detailed research process for this goal is as follow; First step for development of advanced RIAM model is to review for current RIAM model of EPRI. This part describes the overall RIAM methodology including its conceptual model, implementation process, modular approach etc. Second step is to perform feasibility study for current EPRI's RIAM model with case study. This part shows the result of feasibility study for current RIAM method by case study and discussion for result. Finally, concept of Advanced RIAM model is developed based on system dynamics approach and parameter relationship is formulated. In advanced RIAM Model, Identification of scheduled maintenance effect on other parameters and the relationship between PM Activity and failure rate is most important factor. In this study, these relationships are formulated based on system dynamics approach. Creations of these modeling tool using Vensim

  13. REBUILDING THE SOCIAL DIALOGUE AND PROMOTING INCLUSIVE ORGANIZATIONS. A TOOL FOR SOCIAL INNOVATION IN TIMES OF CRISIS

    Directory of Open Access Journals (Sweden)

    Lourdes Munduate

    2014-05-01

    Full Text Available This paper addresses the developing research agenda in the context of the difficulties of the socio-economic environment and its impact on equality policies in the employment context. We present four studies developed in the framework of improving the social dialogue and the promotion of inclusive organizations, highlighting the status of the issue in Spain and its meaning for professional practice. The studies focus on a the need to train and empower social actors - especially workers’ representatives - to lead social innovation and promote inclusive organizations, b proceedings for the current manifestations of what is known as “modern discrimination” in the work context, c labor integration of persons with disabilities, and d supporting policies to balance work and personal life.

  14. ADVANCED 3D LASER MICROSCOPY FOR MEASUREMENTS AND ANALYSIS OF VITRIFIED BONDED ABRASIVE TOOLS

    Directory of Open Access Journals (Sweden)

    WOJCIECH KAPLONEK

    2012-12-01

    Full Text Available In many applications, when a precise non-contact assessment of an abrasive tools’ surface is required, alternative measurement methods are often used. Their use offers numerous advantages (referential method as they introduce new qualities into routinely realized measurements. Over the past few years there has been a dynamic increase in the interest for using new types of classical confocal microscopy. These new types are often defined as 3D laser microscopy. This paper presents select aspects of one such method’s application – confocal laser scanning microscopy – for diagnostic analysis of abrasive tools. In addition this paper also looks at the basis for operation, the origins and the development of this measurement technique.The experimental part of this paper presents the select results of tests carried out on grinding wheel active surfaces with sintered microcrystalline corundum grains SG™ bound with glass-crystalline bond. The 3D laser measuring microscopes LEXT OLS3100 and LEXT OLS4000 by Olympus were used in the experiments. Analysis of the obtained measurement data was carried out in dedicated OLS 5.0.9 and OLS4100 2.1 programs, supported by specialist TalyMap Platinum 5.0 software. The realized experiments confirmed the possibility of using the offered measurement method. This concerns both the assessment of grinding wheel active surfaces and their defects, as well as the internal structures of the tools (grain-bond connections. The method presented is an interesting alternative to the typical methods used in the diagnostics of abrasive tools.

  15. Multi-Hazard Advanced Seismic Probabilistic Risk Assessment Tools and Applications

    International Nuclear Information System (INIS)

    Coleman, Justin L.; Bolisetti, Chandu; Veeraraghavan, Swetha; Parisi, Carlo; Prescott, Steven R.; Gupta, Abhinav

    2016-01-01

    Design of nuclear power plant (NPP) facilities to resist natural hazards has been a part of the regulatory process from the beginning of the NPP industry in the United States (US), but has evolved substantially over time. The original set of approaches and methods was entirely deterministic in nature and focused on a traditional engineering margins-based approach. However, over time probabilistic and risk-informed approaches were also developed and implemented in US Nuclear Regulatory Commission (NRC) guidance and regulation. A defense-in-depth framework has also been incorporated into US regulatory guidance over time. As a result, today, the US regulatory framework incorporates deterministic and probabilistic approaches for a range of different applications and for a range of natural hazard considerations. This framework will continue to evolve as a result of improved knowledge and newly identified regulatory needs and objectives, most notably in response to the NRC activities developed in response to the 2011 Fukushima accident in Japan. Although the US regulatory framework has continued to evolve over time, the tools, methods and data available to the US nuclear industry to meet the changing requirements have not kept pace. Notably, there is significant room for improvement in the tools and methods available for external event probabilistic risk assessment (PRA), which is the principal assessment approach used in risk-informed regulations and risk-informed decision-making applied to natural hazard assessment and design. This is particularly true if PRA is applied to natural hazards other than seismic loading. Development of a new set of tools and methods that incorporate current knowledge, modern best practice, and state-of-the-art computational resources would lead to more reliable assessment of facility risk and risk insights (e.g., the SSCs and accident sequences that are most risk-significant), with less uncertainty and reduced conservatisms.

  16. Multi-Hazard Advanced Seismic Probabilistic Risk Assessment Tools and Applications

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, Justin L. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bolisetti, Chandu [Idaho National Lab. (INL), Idaho Falls, ID (United States); Veeraraghavan, Swetha [Idaho National Lab. (INL), Idaho Falls, ID (United States); Parisi, Carlo [Idaho National Lab. (INL), Idaho Falls, ID (United States); Prescott, Steven R. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Gupta, Abhinav [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-09-01

    Design of nuclear power plant (NPP) facilities to resist natural hazards has been a part of the regulatory process from the beginning of the NPP industry in the United States (US), but has evolved substantially over time. The original set of approaches and methods was entirely deterministic in nature and focused on a traditional engineering margins-based approach. However, over time probabilistic and risk-informed approaches were also developed and implemented in US Nuclear Regulatory Commission (NRC) guidance and regulation. A defense-in-depth framework has also been incorporated into US regulatory guidance over time. As a result, today, the US regulatory framework incorporates deterministic and probabilistic approaches for a range of different applications and for a range of natural hazard considerations. This framework will continue to evolve as a result of improved knowledge and newly identified regulatory needs and objectives, most notably in response to the NRC activities developed in response to the 2011 Fukushima accident in Japan. Although the US regulatory framework has continued to evolve over time, the tools, methods and data available to the US nuclear industry to meet the changing requirements have not kept pace. Notably, there is significant room for improvement in the tools and methods available for external event probabilistic risk assessment (PRA), which is the principal assessment approach used in risk-informed regulations and risk-informed decision-making applied to natural hazard assessment and design. This is particularly true if PRA is applied to natural hazards other than seismic loading. Development of a new set of tools and methods that incorporate current knowledge, modern best practice, and state-of-the-art computational resources would lead to more reliable assessment of facility risk and risk insights (e.g., the SSCs and accident sequences that are most risk-significant), with less uncertainty and reduced conservatisms.

  17. An Innovative Tool for Intraoperative Electron Beam Radiotherapy Simulation and Planning: Description and Initial Evaluation by Radiation Oncologists

    Energy Technology Data Exchange (ETDEWEB)

    Pascau, Javier, E-mail: jpascau@mce.hggm.es [Unidad de Medicina y Cirugia Experimental, Hospital General Universitario Gregorio Maranon, Madrid (Spain); Departamento de Bioingenieria e Ingenieria Aeroespacial, Universidad Carlos III de Madrid, Madrid (Spain); Santos Miranda, Juan Antonio [Servicio de Oncologia Radioterapica, Hospital General Universitario Gregorio Maranon, Madrid (Spain); Facultad de Medicina, Universidad Complutense de Madrid, Madrid (Spain); Calvo, Felipe A. [Servicio de Oncologia Radioterapica, Hospital General Universitario Gregorio Maranon, Madrid (Spain); Facultad de Medicina, Universidad Complutense de Madrid, Madrid (Spain); Departamento de Oncologia, Hospital General Universitario Gregorio Maranon, Madrid (Spain); Bouche, Ana; Morillo, Virgina [Consorcio Hospitalario Provincial de Castellon, Castellon (Spain); Gonzalez-San Segundo, Carmen [Servicio de Oncologia Radioterapica, Hospital General Universitario Gregorio Maranon, Madrid (Spain); Facultad de Medicina, Universidad Complutense de Madrid, Madrid (Spain); Ferrer, Carlos; Lopez Tarjuelo, Juan [Consorcio Hospitalario Provincial de Castellon, Castellon (Spain); and others

    2012-06-01

    Purpose: Intraoperative electron beam radiation therapy (IOERT) involves a modified strategy of conventional radiation therapy and surgery. The lack of specific planning tools limits the spread of this technique. The purpose of the present study is to describe a new simulation and planning tool and its initial evaluation by clinical users. Methods and Materials: The tool works on a preoperative computed tomography scan. A physician contours regions to be treated and protected and simulates applicator positioning, calculating isodoses and the corresponding dose-volume histograms depending on the selected electron energy. Three radiation oncologists evaluated data from 15 IOERT patients, including different tumor locations. Segmentation masks, applicator positions, and treatment parameters were compared. Results: High parameter agreement was found in the following cases: three breast and three rectal cancer, retroperitoneal sarcoma, and rectal and ovary monotopic recurrences. All radiation oncologists performed similar segmentations of tumors and high-risk areas. The average applicator position difference was 1.2 {+-} 0.95 cm. The remaining cancer sites showed higher deviations because of differences in the criteria for segmenting high-risk areas (one rectal, one pancreas) and different surgical access simulated (two rectal, one Ewing sarcoma). Conclusions: The results show that this new tool can be used to simulate IOERT cases involving different anatomic locations, and that preplanning has to be carried out with specialized surgical input.

  18. Its4land - Challenges and Opportunities in Developing Innovative Geospatial Tools for Fit-For-Purpose Land Rights Mapping

    NARCIS (Netherlands)

    Koeva, M.N.; Crommelinck, S.; Stöcker, Claudia; Crompvoets, J.

    2018-01-01

    Mapping millions of unrecorded land rights in large parts of Sub-Saharan Africa remains a challenge. The results of many existing ICT-based approaches for recording these rights have often proven to be inappropriate; therefore, a new generation of tools needs to be developed to map land rights

  19. Concept Mapping as an Innovative Tool for the Assessment of Learning: An Experimental Experience among Business Management Degree Students

    Science.gov (United States)

    Ruiz-Palomino, Pablo; Martinez-Canas, Ricardo

    2013-01-01

    In the search to improve the quality of education at the university level, the use of concept mapping is becoming an important instructional technique for enhancing the teaching-learning process. This educational tool is based on cognitive theories by making a distinction between learning by rote (memorizing) and learning by meaning, where…

  20. Development of innovative tools based on fuelling machine for ageing management of coolant channels of 220 MWe PHWRs

    International Nuclear Information System (INIS)

    Dev, Mahender; Roy, Shyamal; Bhattachrya, Sambit; Singh, Jit Pal; Patel, R.J.; Agarwal, R.G.

    2006-01-01

    PHWR coolant channels are required to be inspected periodically to satisfy the regulatory requirement, to provide information about known or suspected problem and to provide information to assist in future design. This paper describes these tools and techniques, their capabilities and experience of implementing these in reactor site

  1. Development of a web-based tool for the assessment of health and economic outcomes of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA).

    Science.gov (United States)

    Boehler, Christian E H; de Graaf, Gimon; Steuten, Lotte; Yang, Yaling; Abadie, Fabienne

    2015-01-01

    The European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) is a European Commission led policy initiative to address the challenges of demographic change in Europe. For monitoring the health and economic impact of the social and technological innovations carried out by more than 500 stakeholder's groups ('commitments') participating in the EIP on AHA, a generic and flexible web-based monitoring and assessment tool is currently being developed. This paper describes the approach for developing and implementing this web-based tool, its main characteristics and capability to provide specific outcomes that are of value to the developers of an intervention, as well as a series of case studies planned before wider rollout. The tool builds up from a variety of surrogate endpoints commonly used across the diverse set of EIP on AHA commitments in order to estimate health and economic outcomes in terms of incremental changes in quality adjusted life years (QALYs) as well as health and social care utilisation. A highly adaptable Markov model with initially three mutually exclusive health states ('baseline health', 'deteriorated health' and 'death') provides the basis for the tool which draws from an extensive database of epidemiological, economic and effectiveness data; and also allows further customisation through remote data entry enabling more accurate and context specific estimation of intervention impact. Both probabilistic sensitivity analysis and deterministic scenario analysis allow assessing the impact of parameter uncertainty on intervention outcomes. A set of case studies, ranging from the pre-market assessment of early healthcare technologies to the retrospective analysis of established care pathways, will be carried out before public rollout, which is envisaged end 2015. Monitoring the activities carried out within the EIP on AHA requires an approach that is both flexible and consistent in the way health and economic impact is estimated across

  2. Randomized controlled trial of a video decision support tool for cardiopulmonary resuscitation decision making in advanced cancer.

    Science.gov (United States)

    Volandes, Angelo E; Paasche-Orlow, Michael K; Mitchell, Susan L; El-Jawahri, Areej; Davis, Aretha Delight; Barry, Michael J; Hartshorn, Kevan L; Jackson, Vicki Ann; Gillick, Muriel R; Walker-Corkery, Elizabeth S; Chang, Yuchiao; López, Lenny; Kemeny, Margaret; Bulone, Linda; Mann, Eileen; Misra, Sumi; Peachey, Matt; Abbo, Elmer D; Eichler, April F; Epstein, Andrew S; Noy, Ariela; Levin, Tomer T; Temel, Jennifer S

    2013-01-20

    Decision making regarding cardiopulmonary resuscitation (CPR) is challenging. This study examined the effect of a video decision support tool on CPR preferences among patients with advanced cancer. We performed a randomized controlled trial of 150 patients with advanced cancer from four oncology centers. Participants in the control arm (n = 80) listened to a verbal narrative describing CPR and the likelihood of successful resuscitation. Participants in the intervention arm (n = 70) listened to the identical narrative and viewed a 3-minute video depicting a patient on a ventilator and CPR being performed on a simulated patient. The primary outcome was participants' preference for or against CPR measured immediately after exposure to either modality. Secondary outcomes were participants' knowledge of CPR (score range of 0 to 4, with higher score indicating more knowledge) and comfort with video. The mean age of participants was 62 years (standard deviation, 11 years); 49% were women, 44% were African American or Latino, and 47% had lung or colon cancer. After the verbal narrative, in the control arm, 38 participants (48%) wanted CPR, 41 (51%) wanted no CPR, and one (1%) was uncertain. In contrast, in the intervention arm, 14 participants (20%) wanted CPR, 55 (79%) wanted no CPR, and 1 (1%) was uncertain (unadjusted odds ratio, 3.5; 95% CI, 1.7 to 7.2; P advanced cancer who viewed a video of CPR were less likely to opt for CPR than those who listened to a verbal narrative.

  3. Development of tools for safety analysis of control software in advanced reactors

    Energy Technology Data Exchange (ETDEWEB)

    Guarro, S.; Yau, M.; Motamed, M. [Advanced Systems Concepts Associates, El Segundo, CA (United States)

    1996-04-01

    Software based control systems have gained a pervasive presence in a wide variety of applications, including nuclear power plant control and protection systems which are within the oversight and licensing responsibility of the US Nuclear Regulatory Commission. While the cost effectiveness and flexibility of software based plant process control is widely recognized, it is very difficult to achieve and prove high levels of demonstrated dependability and safety assurance for the functions performed by process control software, due to the very flexibility and potential complexity of the software itself. The development of tools to model, analyze and test software design and implementations in the context of the system that the software is designed to control can greatly assist the task of providing higher levels of assurance than those obtainable by software testing alone. This report presents and discusses the development of the Dynamic Flowgraph Methodology (DFM) and its application in the dependability and assurance analysis of software-based control systems. The features of the methodology and full-scale examples of application to both generic process and nuclear power plant control systems are presented and discussed in detail. The features of a workstation software tool developed to assist users in the application of DFM are also described.

  4. Development of tools for safety analysis of control software in advanced reactors

    International Nuclear Information System (INIS)

    Guarro, S.; Yau, M.; Motamed, M.

    1996-04-01

    Software based control systems have gained a pervasive presence in a wide variety of applications, including nuclear power plant control and protection systems which are within the oversight and licensing responsibility of the US Nuclear Regulatory Commission. While the cost effectiveness and flexibility of software based plant process control is widely recognized, it is very difficult to achieve and prove high levels of demonstrated dependability and safety assurance for the functions performed by process control software, due to the very flexibility and potential complexity of the software itself. The development of tools to model, analyze and test software design and implementations in the context of the system that the software is designed to control can greatly assist the task of providing higher levels of assurance than those obtainable by software testing alone. This report presents and discusses the development of the Dynamic Flowgraph Methodology (DFM) and its application in the dependability and assurance analysis of software-based control systems. The features of the methodology and full-scale examples of application to both generic process and nuclear power plant control systems are presented and discussed in detail. The features of a workstation software tool developed to assist users in the application of DFM are also described

  5. Emerging tools for continuous nutrient monitoring networks: Sensors advancing science and water resources protection

    Science.gov (United States)

    Pellerin, Brian; Stauffer, Beth A; Young, Dwane A; Sullivan, Daniel J.; Bricker, Suzanne B.; Walbridge, Mark R; Clyde, Gerard A; Shaw, Denice M

    2016-01-01

    Sensors and enabling technologies are becoming increasingly important tools for water quality monitoring and associated water resource management decisions. In particular, nutrient sensors are of interest because of the well-known adverse effects of nutrient enrichment on coastal hypoxia, harmful algal blooms, and impacts to human health. Accurate and timely information on nutrient concentrations and loads is integral to strategies designed to minimize risk to humans and manage the underlying drivers of water quality impairment. Using nitrate sensors as an example, we highlight the types of applications in freshwater and coastal environments that are likely to benefit from continuous, real-time nutrient data. The concurrent emergence of new tools to integrate, manage and share large data sets is critical to the successful use of nutrient sensors and has made it possible for the field of continuous nutrient monitoring to rapidly move forward. We highlight several near-term opportunities for Federal agencies, as well as the broader scientific and management community, that will help accelerate sensor development, build and leverage sites within a national network, and develop open data standards and data management protocols that are key to realizing the benefits of a large-scale, integrated monitoring network. Investing in these opportunities will provide new information to guide management and policies designed to protect and restore our nation’s water resources.

  6. Modeling and monitoring of pipelines and networks advanced tools for automatic monitoring and supervision of pipelines

    CERN Document Server

    Torres, Lizeth

    2017-01-01

    This book focuses on the analysis and design of advanced techniques for on-line automatic computational monitoring of pipelines and pipe networks. It discusses how to improve the systems’ security considering mathematical models of the flow, historical flow rate and pressure data, with the main goal of reducing the number of sensors installed along a pipeline. The techniques presented in the book have been implemented in digital systems to enhance the abilities of the pipeline network’s operators in recognizing anomalies. A real leak scenario in a Mexican water pipeline is used to illustrate the benefits of these techniques in locating the position of a leak. Intended for an interdisciplinary audience, the book addresses researchers and professionals in the areas of mechanical, civil and control engineering. It covers topics on fluid mechanics, instrumentation, automatic control, signal processing, computing, construction and diagnostic technologies.

  7. Ergonomics evaluation as a powerful tool to redesign advanced interfaces of nuclear control rooms

    International Nuclear Information System (INIS)

    Santos, Isaac J.A.L. dos; Carvalho, Paulo V.R.; Oliveira, Mauro V.; Fernandes, Nelson; Oliveira, Helio C.L.; Grecco, Claudio H.S.; Mol, Antonio C.A.; Augusto, Silas C.; Teixeira, Douglas V.; Ferraz, Fernando T.

    2007-01-01

    Ergonomics is the scientific discipline concerned with the understanding of interactions among humans and other elements of a system. Ergonomics contributes to the design and evaluation of tasks, jobs, products, environments and systems in order to make them compatible with the needs, abilities and limitations of people. In the safe operation of nuclear power plant the performance of the control room crews plays an important role. In this respect, well-designed human-system interfaces (HSI) are crucial for safe and efficient operation of the plant, reducing the occurrence of incidents, accidents and the risks for human error. The aim of this paper is to describe a case study in which a methodological framework was applied to redesign advanced interfaces of a nuclear simulator. (author)

  8. The Advanced Light Source: A new tool for research in atomic physics

    International Nuclear Information System (INIS)

    Schlachter, A.S.

    1990-09-01

    The Advanced Light Source, a third-generation national synchrotron-radiation facility now under construction at the Lawrence Berkeley Laboratory in Berkeley, California, is scheduled to begin serving qualified users across a broad spectrum of research areas in the spring of 1993. Undulators will generate high-brightness, partially coherent, plane polarized, soft-x-ray and ultraviolet (XUV) radiation from below 10 eV to above 2 keV. Wigglers and bend magnets will generate high fluxes of x-rays to photon energies above 10 keV. The ALS will have an extensive research program in which XUV radiation is used to study matter in all its varied gaseous, liquid, and solid forms. 7 refs., 3 figs

  9. NATO Advanced Study Institute on Photophysical and Photochemical Tools in Polymer Science : Conformation, Dynamics, Morphology

    CERN Document Server

    1986-01-01

    In 1980 the New York Academy of Sciences sponsored a three-day conference on luminescence in biological and synthetic macromolecules. After that meeting, Professor Frans DeSchryver and I began to discuss the possibility of organizing a different kind of meeting, with time for both informal and in-depth discussions, to examine certain aspects of the application of fluorescence and phosphorescence spectroscopy to polymers. Our ideas developed through discussions with many others, particularly Professor Lucien Monnerie. By 1983, when we submitted our proposal to NATO for an Advanced Study Institute, the area had grown enormous ly. It is interesting in retrospect to look back on the points which emerged from these discussions as the basis around which the scientific program would be organized and the speakers chosen. We decided early on to focus on applications of these methods to provide information about polymer molecules and polymer systems: The topics would all relate to the conformation and dynamics of macro...

  10. TECHNOLOGICAL ADVANCEMENT OF DEPOSIT WELDING AND GAS LASER CUTTING TO INCREASE THE EFFICIENCY OF THE BIMETALLIC TOOL PRODUCTION

    Directory of Open Access Journals (Sweden)

    Burlachenko Oleg Vasil’evich

    2017-08-01

    Full Text Available Deposit welding is the application of a layer of metal on the surface of a product using fusion welding. In this paper, we consider the method of improving the technology of gas laser cutting, which makes it possible to achieve a high productivity of manufacturing a bimetallic tool. The present paper is concerned with the advantages of gas laser cutting which allows to consider this particular process of separating materials as highly-productive, low-waste, and advanced method of removing allowances of weld-deposit high-speed steel on the working surfaces of bimetallic tool. Urgency of the use of deposit welding and gas laser cutting to improve the efficiency of production of bimetallic tool is shown. The comparative analysis of gas-laser cutting and other cutting methods is given according to the geometrical parameters of cutting and surface quality. Analysis of the results of experimental studies has confirmed the high technological attractiveness and economic efficiency of manufacturing composite structures of punches and matrices when applying deposit welding of cutting parts with high-speed steels. The cost of dimensional processing of the welded cutting part is reduced by 4 to 6 times, while the manufacturing time is reduced by 6 to 12 times.

  11. Using Innovative Knowledge Management Tools for Information Technology Development, Acquisition, and Integration in the United States Army

    Science.gov (United States)

    2007-06-15

    wireless KM tool that suffers from lack of notoriety is the National Security Agency’s (NSA) wireless technology vulnerabilities database ( VAPED ). This...in the unpopularity of programs like the VAPED and the demise of the Quantum Leap exercise. The commercial world is producing even more technology... VAPED , the SDR forum, the WiMAX forum, GCN Labs and others previously cited are examples of readily available government and commercial IT knowledge

  12. Microfluidic chips with multi-junctions: an advanced tool in recovering proteins from inclusion bodies.

    Science.gov (United States)

    Yamaguchi, Hiroshi; Miyazaki, Masaya

    2015-01-01

    Active recombinant proteins are used for studying the biological functions of genes and for the development of therapeutic drugs. Overexpression of recombinant proteins in bacteria often results in the formation of inclusion bodies, which are protein aggregates with non-native conformations. Protein refolding is an important process for obtaining active recombinant proteins from inclusion bodies. However, the conventional refolding method of dialysis or dilution is time-consuming and recovered active protein yields are often low, and a cumbersome trial-and-error process is required to achieve success. To circumvent these difficulties, we used controllable diffusion through laminar flow in microchannels to regulate the denaturant concentration. This method largely aims at reducing protein aggregation during the refolding procedure. This Commentary introduces the principles of the protein refolding method using microfluidic chips and the advantage of our results as a tool for rapid and efficient recovery of active recombinant proteins from inclusion bodies.

  13. Warehousing in the Global Supply Chain Advanced Models, Tools and Applications for Storage Systems

    CERN Document Server

    2012-01-01

    With increased globalization and offshore sourcing, global supply chain management is becoming an important issue for many businesses as it involves a company's worldwide interests and suppliers rather than simply a local or national orientation. The storage systems significantly affect the level of quality of products, the customer’s service level, and the global logistic cost. The mission of warehousing systems design, control and optimization is to effectively ship products in the right place, at the right time, and in the right quantity (i.e. in any configuration) without any damages or alterations, and minimizing costs. Warehousing in the Global Supply Chain presents and discusses a set of models, tools and real applications, including a few case studies rarely presented with a sufficient detail by other literature, to illustrate the main challenges in warehousing activities. This includes all warehouse operations (from receiving to shipping), problems and issues (e.g. storage allocation, assignment,...

  14. A software tool for advanced MRgFUS prostate therapy planning and follow up

    Science.gov (United States)

    van Straaten, Dörte; Hoogenboom, Martijn; van Amerongen, Martinus J.; Weiler, Florian; Issawi, Jumana Al; Günther, Matthias; Fütterer, Jurgen; Jenne, Jürgen W.

    2017-03-01

    US guided HIFU/FUS ablation for the therapy of prostate cancer is a clinical established method, while MR guided HIFU/FUS applications for prostate recently started clinical evaluation. Even if MRI examination is an excellent diagnostic tool for prostate cancer, it is a time consuming procedure and not practicable within an MRgFUS therapy session. The aim of our ongoing work is to develop software to support therapy planning and post-therapy follow-up for MRgFUS on localized prostate cancer, based on multi-parametric MR protocols. The clinical workflow of diagnosis, therapy and follow-up of MR guided FUS on prostate cancer was deeply analyzed. Based on this, the image processing workflow was designed and all necessary components, e.g. GUI, viewer, registration tools etc. were defined and implemented. The software bases on MeVisLab with several implemented C++ modules for the image processing tasks. The developed software, called LTC (Local Therapy Control) will register and visualize automatically all images (T1w, T2w, DWI etc.) and ADC or perfusion maps gained from the diagnostic MRI session. This maximum of diagnostic information helps to segment all necessary ROIs, e.g. the tumor, for therapy planning. Final therapy planning will be performed based on these segmentation data in the following MRgFUS therapy session. In addition, the developed software should help to evaluate the therapy success, by synchronization and display of pre-therapeutic, therapy and follow-up image data including the therapy plan and thermal dose information. In this ongoing project, the first stand-alone prototype was completed and will be clinically evaluated.

  15. Mr-Moose: An advanced SED-fitting tool for heterogeneous multi-wavelength datasets

    Science.gov (United States)

    Drouart, G.; Falkendal, T.

    2018-04-01

    We present the public release of Mr-Moose, a fitting procedure that is able to perform multi-wavelength and multi-object spectral energy distribution (SED) fitting in a Bayesian framework. This procedure is able to handle a large variety of cases, from an isolated source to blended multi-component sources from an heterogeneous dataset (i.e. a range of observation sensitivities and spectral/spatial resolutions). Furthermore, Mr-Moose handles upper-limits during the fitting process in a continuous way allowing models to be gradually less probable as upper limits are approached. The aim is to propose a simple-to-use, yet highly-versatile fitting tool fro handling increasing source complexity when combining multi-wavelength datasets with fully customisable filter/model databases. The complete control of the user is one advantage, which avoids the traditional problems related to the "black box" effect, where parameter or model tunings are impossible and can lead to overfitting and/or over-interpretation of the results. Also, while a basic knowledge of Python and statistics is required, the code aims to be sufficiently user-friendly for non-experts. We demonstrate the procedure on three cases: two artificially-generated datasets and a previous result from the literature. In particular, the most complex case (inspired by a real source, combining Herschel, ALMA and VLA data) in the context of extragalactic SED fitting, makes Mr-Moose a particularly-attractive SED fitting tool when dealing with partially blended sources, without the need for data deconvolution.

  16. Clinical Virtual Reality tools to advance the prevention, assessment, and treatment of PTSD

    Science.gov (United States)

    Rizzo, Albert ‘Skip’; Shilling, Russell

    2017-01-01

    ABSTRACT Numerous reports indicate that the incidence of posttraumatic stress disorder (PTSD) in Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn (OEF/OIF/OND) military personnel has created a significant behavioural healthcare challenge. These findings have served to motivate research on how to better develop and disseminate evidence-based treatments for PTSD. The current article presents the use of Virtual Reality (VR) as a clinical tool to address the assessment, prevention, and treatment of PTSD, based on the VR projects that were evolved at the University of Southern California Institute for Creative Technologies since 2004. A brief discussion of the definition and rationale for the clinical use of VR is followed by a description of a VR application designed for the delivery of prolonged exposure (PE) for treating Service Members (SMs) and Veterans with combat- and sexual assault-related PTSD. The expansion of the virtual treatment simulations of Iraq and Afghanistan for PTSD assessment and prevention is then presented. This is followed by a forward-looking discussion that details early efforts to develop virtual human agent systems that serve the role of virtual patients for training the next generation of clinical providers, as healthcare guides that can be used to support anonymous access to trauma-relevant behavioural healthcare information, and as clinical interviewers capable of automated behaviour analysis of users to infer psychological state. The paper will conclude with a discussion of VR as a tool for breaking down barriers to care in addition to its direct application in assessment and intervention. PMID:29372007

  17. Clinical Virtual Reality tools to advance the prevention, assessment, and treatment of PTSD.

    Science.gov (United States)

    Rizzo, Albert 'Skip'; Shilling, Russell

    2017-01-01

    Numerous reports indicate that the incidence of posttraumatic stress disorder (PTSD) in Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn (OEF/OIF/OND) military personnel has created a significant behavioural healthcare challenge. These findings have served to motivate research on how to better develop and disseminate evidence-based treatments for PTSD. The current article presents the use of Virtual Reality (VR) as a clinical tool to address the assessment, prevention, and treatment of PTSD, based on the VR projects that were evolved at the University of Southern California Institute for Creative Technologies since 2004. A brief discussion of the definition and rationale for the clinical use of VR is followed by a description of a VR application designed for the delivery of prolonged exposure (PE) for treating Service Members (SMs) and Veterans with combat- and sexual assault-related PTSD. The expansion of the virtual treatment simulations of Iraq and Afghanistan for PTSD assessment and prevention is then presented. This is followed by a forward-looking discussion that details early efforts to develop virtual human agent systems that serve the role of virtual patients for training the next generation of clinical providers, as healthcare guides that can be used to support anonymous access to trauma-relevant behavioural healthcare information, and as clinical interviewers capable of automated behaviour analysis of users to infer psychological state. The paper will conclude with a discussion of VR as a tool for breaking down barriers to care in addition to its direct application in assessment and intervention.

  18. Thermal plumes and micro-contaminants release from power plants in water bodies. Development of innovative software tools to support plant management and real case applications

    International Nuclear Information System (INIS)

    Guandalini, R.

    2007-01-01

    Environmental issues are a fundamental aspect of energy generation by thermal power plants. Numerical modeling can be used to develop innovative software tools to support plant management and to analyze critical scenarios also considering meteorology forecasts. Compliance with regulatory obligations of thermal/contaminant plumes and prediction of water body physical properties at the intake/discharge location can be performed by real time systems, in order to optimize plant operations and to evaluate the amount of energy that will be generated. A procedure coupling hydrodynamic and water quality modeling for the prediction of possible areas of accumulation of micro-contaminants in a short, medium and long period is also presented. Finally, applications of thermal/pollutant prediction systems and numerical modeling of particular environmental aspects of energy production and transport are shown (e.g. chlorine diffusion from a HVDC marine anode, impact on aquatic ecosystems in coastal regions). (author)

  19. Advancing spaceborne tools for the characterization of planetary ionospheres and circumstellar environments

    Science.gov (United States)

    Douglas, Ewan Streets

    This work explores remote sensing of planetary atmospheres and their circumstellar surroundings. The terrestrial ionosphere is a highly variable space plasma embedded in the thermosphere. Generated by solar radiation and predominantly composed of oxygen ions at high altitudes, the ionosphere is dynamically and chemically coupled to the neutral atmosphere. Variations in ionospheric plasma density impact radio astronomy and communications. Inverting observations of 83.4 nm photons resonantly scattered by singly ionized oxygen holds promise for remotely sensing the ionospheric plasma density. This hypothesis was tested by comparing 83.4 nm limb profiles recorded by the Remote Atmospheric and Ionospheric Detection System aboard the International Space Station to a forward model driven by coincident plasma densities measured independently via ground-based incoherent scatter radar. A comparison study of two separate radar overflights with different limb profile morphologies found agreement between the forward model and measured limb profiles. A new implementation of Chapman parameter retrieval via Markov chain Monte Carlo techniques quantifies the precision of the plasma densities inferred from 83.4 nm emission profiles. This first study demonstrates the utility of 83.4 nm emission for ionospheric remote sensing. Future visible and ultraviolet spectroscopy will characterize the composition of exoplanet atmospheres; therefore, the second study advances technologies for the direct imaging and spectroscopy of exoplanets. Such spectroscopy requires the development of new technologies to separate relatively dim exoplanet light from parent star light. High-contrast observations at short wavelengths require spaceborne telescopes to circumvent atmospheric aberrations. The Planet Imaging Concept Testbed Using a Rocket Experiment (PICTURE) team designed a suborbital sounding rocket payload to demonstrate visible light high-contrast imaging with a visible nulling coronagraph

  20. Advanced fuelling system for use as a burn control tool in a burning plasma device

    Energy Technology Data Exchange (ETDEWEB)

    Raman, R. [Washington Univ., Seattle, WA (United States)

    2007-07-01

    Steady-state Advanced Tokamak (AT) scenarios rely on optimized density and pressure profiles to maximize the bootstrap current fraction. Under this mode of operation, the fuelling system must deposit small amounts of fuel where it is needed, and as often as needed, so as to compensate for fuel losses, but not to adversely alter the established density and pressure profiles. Conventional fuelling methods have not demonstrated successful fuelling of ATtype discharges and may be incapable of deep fuelling long pulse ELM-free discharges in ITER. The capability to deposit fuel at any desired radial location within the tokamak would provide burn control capability through alteration of the density profile. The ability to peak the density profile would ease ignition requirements, while operating ITER with density profiles that are peaked would increase the fusion power output. An advanced fuelling system should also be capable of fuelling well past internal transport barriers. Compact Toroid (CT) fuelling [R. Raman, et al., 'Experimental demonstration of tokamak fuelling by compact toroid injection,' Nucl. Fusion, 37, 967 (1997)] has the potential to meet these needs, while simultaneously providing a source of toroidal momentum input. A CT is a selfcontained toroidal plasmoid with embedded magnetic fields. The 20 Hz injector consists of the formation region, compression, acceleration and transport regions. Fuel gas is puffed into the formation region, and a combination of magnetic field and electric current ionizes this gas and creates a self-contained plasma ring (the 'CT'). Then a fast current pulse compresses and accelerates the CT by electromagnetic forces. The accelerated CT will travel at a speed of over 30 cm/{mu}s and for reactors will create a particle inventory perturbation of < 1% per pulse. At this level of particle inventory perturbation, optimized density profiles will not be adversely perturbed. Experimental data needed for the design of

  1. Myositis registries and biorepositories: powerful tools to advance clinical, epidemiologic and pathogenic research.

    Science.gov (United States)

    Rider, Lisa G; Dankó, Katalin; Miller, Frederick W

    2014-11-01

    Clinical registries and biorepositories have proven extremely useful in many studies of diseases, especially rare diseases. Given their rarity and diversity, the idiopathic inflammatory myopathies, or myositis syndromes, have benefited from individual researchers' collections of cohorts of patients. Major efforts are being made to establish large registries and biorepositories that will allow many additional studies to be performed that were not possible before. Here, we describe the registries developed by investigators and patient support groups that are currently available for collaborative research purposes. We have identified 46 myositis research registries, including many with biorepositories, which have been developed for a wide variety of purposes and have resulted in great advances in understanding the range of phenotypes, clinical presentations, risk factors, pathogenic mechanisms, outcome assessment, therapeutic responses, and prognoses. These are now available for collaborative use to undertake additional studies. Two myositis patient registries have been developed for research, and myositis patient support groups maintain demographic registries with large numbers of patients available to be contacted for potential research participation. Investigator-initiated myositis research registries and biorepositories have proven extremely useful in understanding many aspects of these rare and diverse autoimmune diseases. These registries and biorepositories, in addition to those developed by myositis patient support groups, deserve continued support to maintain the momentum in this field as they offer major opportunities to improve understanding of the pathogenesis and treatment of these diseases in cost-effective ways.

  2. The Advanced Light Source at Lawrence Berkeley Laboratory: a new tool for research in atomic physics

    International Nuclear Information System (INIS)

    Schlachter, A.S.; Robinson, A.L.

    1991-01-01

    The Advanced Light Source, a third-generation national synchrotron-radiation facility now under construction at the Lawrence Berkeley Laboratory, is scheduled to begin serving qualified users across a broad spectrum of research areas in the spring of 1993. Based on a low-emittance electron storage ring optimized to operate at 1.5 GeV, the ALS will have 10 long straight sections available for insertion devices (undulators and wigglers) and 24 high-quality bend-magnet ports. The short pulse width (30-50 ps) will be ideal for time-resolved measurements. Undulators will generate high-brightness partially coherent soft X-ray and ultraviolet (XUV) radiation from below 10 eV to above 2 keV; this radiation is plane polarized. Wigglers and bend magnets will extend the spectrum by generating high fluxes of X-rays to photon energies above 10 keV. The ALS will have an extensive research program in which XUV radiation is used to study matter in allk its varied gaseous, liquid, and solid forms. The high brightness will open new areas of research in the materials sciences, such as spatially resolved spectroscopy (spectromicroscopy), and in biology, such as X-ray microscopy with element-specific sensitivity; the high flux will allow measurements in atomic physics and chemistry to be made with tenuous gas-phase targets. Technological applications could include lithography and nano-fabrication. (orig.)

  3. The weak-ties in advanced business services as a major force of innovation and diffusion; Las Eak-Ties en los servicios avanzados a empresas como factor relevante de la innovacion y su difusion

    Energy Technology Data Exchange (ETDEWEB)

    Almenar i Llongo, V.; Hernandez Sancho, F.; Solar i Marco, V.

    2012-07-01

    This paper tries to expose the role of weak-ties of advanced business services in both mechanisms which generate innovation as well as allow technological diffusion and transfer of innovations (spillovers). Assuming that the latest information generally flows to agents through weak ties, the Weak-Ties Hypothesis (WTH) is an approach that helps to explain the importance of the relations with the environment in the process of innovation and generation of new knowledge and its implementation and dissemination, evaluating the synergy's resulting from cooperation between agents. (Author) 21 refs.

  4. Tool for evaluating the evolution Space Weather Regional Warning Centers under the innovation point of view: the Case Study of the Embrace Space Weather Program Early Stages

    Science.gov (United States)

    Denardini, Clezio Marcos

    2016-07-01

    We have developed a tool for measuring the evolutional stage of the space weather regional warning centers using the approach of the innovative evolution starting from the perspective presented by Figueiredo (2009, Innovation Management: Concepts, metrics and experiences of companies in Brazil. Publisher LTC, Rio de Janeiro - RJ). It is based on measuring the stock of technological skills needed to perform a certain task that is (or should) be part of the scope of a space weather center. It also addresses the technological capacity for innovation considering the accumulation of technological and learning capabilities, instead of the usual international indices like number of registered patents. Based on this definition, we have developed a model for measuring the capabilities of the Brazilian Study and Monitoring Program Space Weather (Embrace), a program of the National Institute for Space Research (INPE), which has gone through three national stages of development and an international validation step. This program was created in 2007 encompassing competence from five divisions of INPE in order to carry out the data collection and maintenance of the observing system in space weather; to model processes of the Sun-Earth system; to provide real-time information and to forecast space weather; and provide diagnostic their effects on different technological systems. In the present work, we considered the issues related to the innovation of micro-processes inherent to the nature of the Embrace program, not the macro-economic processes, despite recognizing the importance of these. During the development phase, the model was submitted to five scientists/managers from five different countries member of the International Space Environment Service (ISES) who presented their evaluations, concerns and suggestions. It was applied to the Embrace program through an interview form developed to be answered by professional members of regional warning centers. Based on the returning

  5. Teaching Groups as Foci for Evaluating Performance in Cost-Effectiveness of GCE Advanced Level Provision: Some Practical Methodological Innovations.

    Science.gov (United States)

    Fielding, Antony

    2002-01-01

    Analyzes subject teaching-group effectiveness in English and Welsh General Certification of Education (GCE) Advanced Level prior to a linking to resources; suggests cross-classified multilevel models with weighted random effects for disentangling student, group, and teacher effects; finds that teacher effects are considerable, but cannot find…

  6. TU-CD-304-11: Veritas 2.0: A Cloud-Based Tool to Facilitate Research and Innovation

    Energy Technology Data Exchange (ETDEWEB)

    Mishra, P; Patankar, A; Etmektzoglou, A; Svatos, M [Varian Medical Systems, Palo Alto, CA (United States); Lewis, J [Brigham and Women’s Hospital, Boston, MA (United States)

    2015-06-15

    Purpose: We introduce Veritas 2.0, a cloud-based, non-clinical research portal, to facilitate translation of radiotherapy research ideas to new delivery techniques. The ecosystem of research tools includes web apps for a research beam builder for TrueBeam Developer Mode, an image reader for compressed and uncompressed XIM files, and a trajectory log file based QA/beam delivery analyzer. Methods: The research beam builder can generate TrueBeam readable XML file either from scratch or from pre-existing DICOM-RT plans. DICOM-RT plan is first converted to XML format and then researcher can interactively modify or add control points to them. Delivered beam can be verified via reading generated images and analyzing trajectory log files. Image reader can read both uncompressed and HND-compressed XIM images. The trajectory log analyzer lets researchers plot expected vs. actual values and deviations among 30 mechanical axes. The analyzer gives an animated view of MLC patterns for the beam delivery. Veritas 2.0 is freely available and its advantages versus standalone software are i) No software installation or maintenance needed, ii) easy accessibility across all devices iii) seamless upgrades and iv) OS independence. Veritas is written using open-source tools like twitter bootstrap, jQuery, flask, and Python-based modules. Results: In the first experiment, an anonymized 7-beam DICOM-RT IMRT plan was converted to XML beam containing 1400 control points. kV and MV imaging points were inserted into this XML beam. In another experiment, a binary log file was analyzed to compare actual vs expected values and deviations among axes. Conclusions: Veritas 2.0 is a public cloud-based web app that hosts a pool of research tools for facilitating research from conceptualization to verification. It is aimed at providing a platform for facilitating research and collaboration. I am full time employee at Varian Medical systems, Palo Alto.

  7. TU-CD-304-11: Veritas 2.0: A Cloud-Based Tool to Facilitate Research and Innovation

    International Nuclear Information System (INIS)

    Mishra, P; Patankar, A; Etmektzoglou, A; Svatos, M; Lewis, J

    2015-01-01

    Purpose: We introduce Veritas 2.0, a cloud-based, non-clinical research portal, to facilitate translation of radiotherapy research ideas to new delivery techniques. The ecosystem of research tools includes web apps for a research beam builder for TrueBeam Developer Mode, an image reader for compressed and uncompressed XIM files, and a trajectory log file based QA/beam delivery analyzer. Methods: The research beam builder can generate TrueBeam readable XML file either from scratch or from pre-existing DICOM-RT plans. DICOM-RT plan is first converted to XML format and then researcher can interactively modify or add control points to them. Delivered beam can be verified via reading generated images and analyzing trajectory log files. Image reader can read both uncompressed and HND-compressed XIM images. The trajectory log analyzer lets researchers plot expected vs. actual values and deviations among 30 mechanical axes. The analyzer gives an animated view of MLC patterns for the beam delivery. Veritas 2.0 is freely available and its advantages versus standalone software are i) No software installation or maintenance needed, ii) easy accessibility across all devices iii) seamless upgrades and iv) OS independence. Veritas is written using open-source tools like twitter bootstrap, jQuery, flask, and Python-based modules. Results: In the first experiment, an anonymized 7-beam DICOM-RT IMRT plan was converted to XML beam containing 1400 control points. kV and MV imaging points were inserted into this XML beam. In another experiment, a binary log file was analyzed to compare actual vs expected values and deviations among axes. Conclusions: Veritas 2.0 is a public cloud-based web app that hosts a pool of research tools for facilitating research from conceptualization to verification. It is aimed at providing a platform for facilitating research and collaboration. I am full time employee at Varian Medical systems, Palo Alto

  8. Applied acoustics concepts, absorbers, and silencers for acoustical comfort and noise control alternative solutions, innovative tools, practical examples

    CERN Document Server

    Fuchs, Helmut V

    2013-01-01

    The author gives a comprehensive overview of materials and components for noise control and acoustical comfort. Sound absorbers must meet acoustical and architectural requirements, which fibrous or porous material alone can meet. Basics and applications are demonstrated, with representative examples for spatial acoustics, free-field test facilities and canal linings. Acoustic engineers and construction professionals will find some new basic concepts and tools for developments in order to improve acoustical comfort. Interference absorbers, active resonators and micro-perforated absorbers of different materials and designs complete the list of applications.

  9. AULA-Advanced Virtual Reality Tool for the Assessment of Attention: Normative Study in Spain.

    Science.gov (United States)

    Iriarte, Yahaira; Diaz-Orueta, Unai; Cueto, Eduardo; Irazustabarrena, Paula; Banterla, Flavio; Climent, Gema

    2016-06-01

    The present study describes the obtention of normative data for the AULA test, a virtual reality tool designed to evaluate attention problems, especially in children and adolescents. The normative sample comprised 1,272 participants (48.2% female) with an age range from 6 to 16 years (M = 10.25, SD = 2.83). The AULA test administered to them shows both visual and auditory stimuli, while randomized distractors of ecological nature appear progressively. Variables provided by AULA were clustered in different categories for their posterior analysis. Differences by age and gender were analyzed, resulting in 14 groups, 7 per sex group. Differences between visual and auditory attention were also obtained. Obtained normative data are relevant for the use of AULA for evaluating attention in Spanish children and adolescents in a more ecological way. Further studies will be needed to determine sensitivity and specificity of AULA to measure attention in different clinical populations. (J. of Att. Dis. 2016; 20(6) 542-568). © The Author(s) 2012.

  10. A new tool to give hospitalists feedback to improve interprofessional teamwork and advance patient care.

    Science.gov (United States)

    Chesluk, Benjamin J; Bernabeo, Elizabeth; Hess, Brian; Lynn, Lorna A; Reddy, Siddharta; Holmboe, Eric S

    2012-11-01

    Teamwork is a vital skill for health care professionals, but the fragmented systems within which they work frequently do not recognize or support good teamwork. The American Board of Internal Medicine has developed and is testing the Teamwork Effectiveness Assessment Module (TEAM), a tool for physicians to evaluate how they perform as part of an interprofessional patient care team. The assessment provides hospitalist physicians with feedback data drawn from their own work of caring for patients, in a way that is intended to support immediate, concrete change efforts to improve the quality of patient care. Our approach demonstrates the value of looking at teamwork in the real world of health care-that is, as it occurs in the actual contexts in which providers work together to care for patients. The assessment of individual physicians' teamwork competencies may play a role in the larger effort to bring disparate health professions together in a system that supports and rewards a team approach in hope of improving patient care.

  11. Genome editing in plants: Advancing crop transformation and overview of tools.

    Science.gov (United States)

    Shah, Tariq; Andleeb, Tayyaba; Lateef, Sadia; Noor, Mehmood Ali

    2018-05-07

    Genome manipulation technology is one of emerging field which brings real revolution in genetic engineering and biotechnology. Targeted editing of genomes pave path to address a wide range of goals not only to improve quality and productivity of crops but also permit to investigate the fundamental roots of biological systems. These goals includes creation of plants with valued compositional properties and with characters that confer resistance to numerous biotic and abiotic stresses. Numerous novel genome editing systems have been introduced during the past few years; these comprise zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats/Cas9 (CRISPR/Cas9). Genome editing technique is consistent for improving average yield to achieve the growing demands of the world's existing food famine and to launch a feasible and environmentally safe agriculture scheme, to more specific, productive, cost-effective and eco-friendly. These exciting novel methods, concisely reviewed herein, have verified themselves as efficient and reliable tools for the genetic improvement of plants. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

  12. Measuring the Benefits of Public Chargers and Improving Infrastructure Deployments Using Advanced Simulation Tools: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Wood, Eric; Neubauer. Jeremy; Burton, Evan

    2015-02-01

    With support from the U.S. Department of Energy's Vehicle Technologies Office, the National Renewable Energy Laboratory developed BLAST-V -- the Battery Lifetime Analysis and Simulation Tool for Vehicles. The addition of high-resolution spatial-temporal travel histories enables BLAST-V to investigate user-defined infrastructure rollouts of publically accessible charging infrastructure, as well as quantify impacts on vehicle and station owners in terms of improved vehicle utility and station throughput. This paper presents simulation outputs from BLAST-V that quantify the utility improvements of multiple distinct rollouts of publically available Level 2 electric vehicle supply equipment (EVSE) in the Seattle, Washington, metropolitan area. Publically available data on existing Level 2 EVSE are also used as an input to BLAST-V. The resulting vehicle utility is compared to a number of mock rollout scenarios. Discussion focuses on the estimated number of Level 2 stations necessary to substantially increase vehicle utility and how stations can be strategically sited to maximize their potential benefit to prospective electric vehicle owners.

  13. ASTRID© - Advanced Solar Tubular ReceIver Design: A powerful tool for receiver design and optimization

    Science.gov (United States)

    Frantz, Cathy; Fritsch, Andreas; Uhlig, Ralf

    2017-06-01

    In solar tower power plants the receiver is one of the critical components. It converts the solar radiation into heat and must withstand high heat flux densities and high daily or even hourly gradients (due to passage of clouds). For this reason, the challenge during receiver design is to find a reasonable compromise between receiver efficiency, reliability, lifetime and cost. There is a strong interaction between the heliostat field, the receiver and the heat transfer fluid. Therefore, a proper receiver design needs to consider these components within the receiver optimization. There are several design and optimization tools for receivers, but most of them focus only on the receiver, ignoring the heliostat field and other parts of the plant. During the last years DLR developed the ASTRIDcode for tubular receiver concept simulation. The code comprises both a high and a low-detail model. The low-detail model utilizes a number of simplifications which allow the user to screen a high number of receiver concepts for optimization purposes. The high-detail model uses a FE model and is able to compute local absorber and salt temperatures with high accuracy. One key strength of the ASTRIDcode is its interface to a ray tracing software which simulates a realistic heat flux distributions on the receiver surface. The results generated by the ASTRIDcode have been validated by CFD simulations and measurement data.

  14. Advanced semi-active engine and transmission mounts: tools for modelling, analysis, design, and tuning

    Science.gov (United States)

    Farjoud, Alireza; Taylor, Russell; Schumann, Eric; Schlangen, Timothy

    2014-02-01

    This paper is focused on modelling, design, and testing of semi-active magneto-rheological (MR) engine and transmission mounts used in the automotive industry. The purpose is to develop a complete analysis, synthesis, design, and tuning tool that reduces the need for expensive and time-consuming laboratory and field tests. A detailed mathematical model of such devices is developed using multi-physics modelling techniques for physical systems with various energy domains. The model includes all major features of an MR mount including fluid dynamics, fluid track, elastic components, decoupler, rate-dip, gas-charged chamber, MR fluid rheology, magnetic circuit, electronic driver, and control algorithm. Conventional passive hydraulic mounts can also be studied using the same mathematical model. The model is validated using standard experimental procedures. It is used for design and parametric study of mounts; effects of various geometric and material parameters on dynamic response of mounts can be studied. Additionally, this model can be used to test various control strategies to obtain best vibration isolation performance by tuning control parameters. Another benefit of this work is that nonlinear interactions between sub-components of the mount can be observed and investigated. This is not possible by using simplified linear models currently available.

  15. Advanced Online Survival Analysis Tool for Predictive Modelling in Clinical Data Science.

    Science.gov (United States)

    Montes-Torres, Julio; Subirats, José Luis; Ribelles, Nuria; Urda, Daniel; Franco, Leonardo; Alba, Emilio; Jerez, José Manuel

    2016-01-01

    One of the prevailing applications of machine learning is the use of predictive modelling in clinical survival analysis. In this work, we present our view of the current situation of computer tools for survival analysis, stressing the need of transferring the latest results in the field of machine learning to biomedical researchers. We propose a web based software for survival analysis called OSA (Online Survival Analysis), which has been developed as an open access and user friendly option to obtain discrete time, predictive survival models at individual level using machine learning techniques, and to perform standard survival analysis. OSA employs an Artificial Neural Network (ANN) based method to produce the predictive survival models. Additionally, the software can easily generate survival and hazard curves with multiple options to personalise the plots, obtain contingency tables from the uploaded data to perform different tests, and fit a Cox regression model from a number of predictor variables. In the Materials and Methods section, we depict the general architecture of the application and introduce the mathematical background of each of the implemented methods. The study concludes with examples of use showing the results obtained with public datasets.

  16. Assistance tools for generic definition of ITER maintenance tasks and scenarios in advanced supervisory control systems

    International Nuclear Information System (INIS)

    Zieba, Stéphane; Russotto, François-Xavier; Da Silva Simoes, Max; Measson, Yvan

    2013-01-01

    Highlights: ► Improve supervisory control systems for ITER in-vessel and hot cell maintenance. ► Optimize remote handling operations effectiveness, reliability and safety. ► Provide a generic description of the maintenance tasks and scenarios. ► Development of context-based assistances for operators and supervisor. ► Improvement of operator's situation awareness. -- Abstract: This paper concerns the improvement of supervisory control systems in the context of remote handling for the maintenance tasks in ITER. This work aims at providing a single formalism and tools to define in a generic way the ITER maintenance tasks and scenarios for in-vessel and hot cell operations. A three-layered approach is proposed to model these tasks and scenarios. Physical actions are defined for the scene elements. From these physical actions, behaviours are defined to represent high-level functionalities. Finally, interaction modes define the way that behaviours are achieved in terms of human–machine interactions. Case study concerning the blanket maintenance procedure is discussed concerning the contributions of the descriptive model and the context-based assistances to the activities of supervisory control

  17. Lidars as an operational tool for meteorology and advanced atmospheric research

    Science.gov (United States)

    Simeonov, Valentin; Dinoev, Todor; Serikov, Ilya; Froidevaux, Martin; Bartlome, Marcel; Calpini, Bertrand; Bobrovnikov, Sergei; Ristori, Pablo; van den Bergh, Hubert; Parlange, Marc; Archinov, Yury

    2010-05-01

    The talk will present the concept and observation results of three advanced lidar systems developed recently at the Swiss federal Institute of Technology- Lausanne (EPFL) Switzerland. Two of the systems are Raman lidars for simultaneous water vapor, temperature and aerosol observations and the third one is an ozone UV DIAL system. The Ranan lidars use vibrational water vapor and nitrogen signals to derive water vapor mixing ratio and temperature, aerosol extinction and backscatter are measured using pure-rotational Raman and elastic signals. The first Raman lidar (RALMO) is a fully automated, water vapor /temperature/aerosol lidar developed for operational use by the Swiss meteorological office (MeteoSiss). The lidar supplies water vapor mixing ratio and temperature plus aerosol extinction and backscatter coefficients at 355 nm. The operational range of the lidar is 100-7000 m (night time) and 100- 5000 m (daytime) with time resolution of 30 min. The spatial resolution varies with height from 25 to 300 m in order to maintain the maximum measurement error of 10%. The system is designed to provide long-term database with minimal instrument-induced variations in time of the measured parameters. The lidar has been in regular operation in the main aerological station of Meteoswiss- Payerne since September 2008. The second Raman lidar is a new generation, solar-blind system with an operational range 10-500 m and high spatial (1.5 m) and temporal (1 s) resolutions designed for simultaneous humidity, temperature, and aerosol measurements in the lower atmosphere. To maintain the measurement accuracy while operating with fixed spatial and temporal resolution, the receiver is designed to provide lower than ten dynamic range of the signals within the distance range of the lidar. The lidar has 360° azimuth and 240°elevation scanning ability. The lidar was used in two field campaigns aiming to study the structure of the lower atmosphere over complex terrains and, in particular

  18. Methods and tools for the evaluation of the sensitivity to natural radiations of advanced integrated circuits

    International Nuclear Information System (INIS)

    Peronnard, P.

    2009-10-01

    Atmospheric neutrons, whose fluxes and energies dependent on the altitude, the sun activity and the geographic coordinates, have been identified as being capable to provoke SEE (Single Event Effects), by indirect ionisation, in integrated devices issued from advanced manufacturing processes (nano-metric devices). This concerns not only avionics but also applications operating at ground level. The evaluation of the sensitivity to SEE provoked by natural radiation becomes thus a mandatory step during the selection of devices devoted to be included in applications requiring high reliability. The sensitivity to SEE can be mitigated by different approaches at different levels from manufacturing level (use of particular process technologies such as SOI - Silicon On Isolator -) to the system level (hardware/software redundancy). Independently of the adopted hardening approach, the so-called radiation ground testing are mandatory to evaluate the error rates of a device or a system. During such tests, the DUT (Device Under Test) is exposed to a flux of particles while it performs a given activity. For SEU (Single Event Upsets) radiation ground testing, two main strategies exist: static test: the circuit areas which are supposed to be sensitive to SEUs (registers, memories,...) are initialized with a reference pattern. The content of the sensitive area is periodically compared to the reference pattern to identify potential SEU. Dynamic test: the DUT performs an activity representative of the one it will execute during the final application. Static test: strategies are frequently adopted as they provide the intrinsic sensitivity, in terms of the average number of particles needed to provoke an SEU, of different sensitive areas of the device. From such a strategy can thus be obtained a 'worst case estimation' of the device sensitivity. This thesis aims at giving a description and validating the methodologies required to estimate the sensitivity to radiations of two types of

  19. «GREEN» LOGISTICS AS A TOOL TO ENSURE ENVIRONMENTAL SECURITY AND INSTITUTIONAL INNOVATION SUBSOIL EUROPEAN ARCTIC

    Directory of Open Access Journals (Sweden)

    M. N. Dudin

    2016-01-01

    Full Text Available This article is an overview of the major logistics and technology solutions to be implemented to streamline the subsoil use in the European Arctic. The theme of this work is very urgent, because Russia, despite the high resource base is underdeveloped institutional framework and resource extraction is characterized by the maximum level of loss of potential gross value of the hydrocarbon potential.The purpose of this article is to study Russian priorities at national and regional level, related to mining, through the use of «green» logistics as an instrument for environmental safety and institutional innovation subsoil of the European Arctic.Methodology. The methodological basis of this article are comparative, economic and statistical analysis methods.The results of this paper have become the solutions to problems, to achieve this goal, in particular: a substantiated conclusion that the Arctic is a world heritage and «climate laboratory» of the planet, so the development of the resource, industrial, transport and logistics potential of the region need to be based on «green» technologies; The article describes four environmentally-oriented direction (creating material and technical base, the formation of a safe icebreaker fleet, the development of new navigation and communication systems, power supply, which will enable to master the industrial, transport and logistics potential of the Arctic with minimal anthropogenic load.Conclusions. The following basic conclusions were as follows: first, subarctic and arctic areas are world heritage, so the development of deposits on them should be in the interest of the world community on a non-discriminatory  basis; secondly, hydrocarbon reserves, concentrated in the European Arctic, currently can not be extracted without environmental impacts, access to these resources is limited due to lack of development of the transport component, therefore, should be used aggressive techniques of extraction of

  20. Focused beam reflectance method as an innovative (PAT) tool to monitor in-line granulation process in fluidized bed.

    Science.gov (United States)

    Alshihabi, Firas; Vandamme, Thierry; Betz, Gabriele

    2013-02-01

    Fluidized bed granulation is a commonly used unit operation in the pharmaceutical industry. But still to obtain and control the desired granule size is challenging due to many process variables affecting the final product. Focused beam reflectance measurement (FBRM, Mettler-Toledo, Switzerland) is an increasingly popular particle growth analysis technique. FBRM tool was installed in two different locations inside a fluidized bed granulator (GPCG2, Glatt, Binzen) in order to monitor the granulation growth kinetics. An experimental design was created to study the effect of process variables using FBRM probe and comparing the results with the one's measured by sieve analysis. The probe location is of major importance to get smooth and robust curves. The excess feeding of binder solution might lead to agglomeration and thus to process collapse, however this phenomenon was clearly detected with FBRM method. On the other hand, the process variables at certain levels might affect the FBRM efficiency by blocking the probe window with sticky particles. A good correlation was obtained (R(2) = 0.95) between FBRM and sieve analysis mean particle size. The proposed in-line monitoring tool enables the operator to select appropriate process parameters and control the wet granulation process more efficiently.