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Sample records for incidental finding lca

  1. Incidental findings in musculoskeletal radiology

    International Nuclear Information System (INIS)

    Wuennemann, F.; Rehnitz, C.; Weber, M.A.

    2017-01-01

    Increasing numbers of conventional X-rays, computed tomography and magnetic resonance imaging in the inpatient, outpatient and scientific routine leads to an increasing number of incidental findings. The correct interpretation of these incidental findings with respect to the relevance and the evaluation concerning further work-up is an important task of radiologists. Description of common incidental findings in musculoskeletal imaging and their clinical classification. A PubMed literature search was performed using the following terms: incidental findings, population-based imaging, musculoskeletal imaging, non-ossifying fibroma, enchondroma, osteodystrophia deformans, chondrosarcoma, fibrous dysplasia, simple bone cyst, unicameral bone cyst, solitary bone cyst, aneurysmal bone cyst, vertebral hemangioma, bone island, osteopoikilosis, Tarlov cyst and diffuse idiopathic skeletal hyperostosis (DISH). Incidental findings are observed in up to 40% of imaging procedures. In up to 6% these incidental findings involve the skeletal system. Common incidental findings are discussed and their clinical relevance is explained. (orig.) [de

  2. Incidental findings on MRI of the spine

    Energy Technology Data Exchange (ETDEWEB)

    Kamath, S.; Jain, N.; Goyal, N.; Mansour, R. [Department of Radiology, University Hospital of Wales, Cardiff (United Kingdom); Mukherjee, K. [Department of Radiology, University Hospital of Wales, Cardiff (United Kingdom)], E-mail: kausikmukherjee@doctors.org.uk

    2009-04-15

    MRI is widely used as the imaging of choice for spinal disorders and may reveal either a clinically insignificant incidental abnormality or a significant lesion, unrelated to the spine, which may explain the patient's symptoms. This article attempts to establish the importance of such findings and describes a sensible approach to the reporting of MRI examinations of the spine with special attention to the incidental findings commonly encountered. The MRI characteristics of such findings are briefly described.

  3. Fetal MRI: incidental findings in the mother

    International Nuclear Information System (INIS)

    Abdullah, Selwan B.; Dietz, Kelly R.; Holm, Tara L.

    2016-01-01

    Fetal magnetic resonance imaging (MRI) is a routinely used tool in prenatal diagnosis; however, there is a lack of studies evaluating incidental findings observed in the mother. This study describes and quantifies incidental findings observed in the mother during fetal MRI. We reviewed all fetal MRI studies at the University of Minnesota Medical Center from February 2008 to September 2014. Two pediatric radiologists retrospectively conducted a consensus evaluation. The maternal findings were categorized into neurologic, gynecologic, urinary, gastrointestinal and musculoskeletal. Hydronephrosis consistent with the stage of pregnancy was recorded but was not included as an abnormal finding. Abnormal findings were classified into three groups, depending on their clinical significance: level I (low), level II (medium) and level III (high). We evaluated 332 pregnant patients with a mean age of 29.3 years and a mean gestational age of 29 weeks. Of these, 55.4% had at least 1 incidental finding, for a total of 262 incidental maternal findings. Of the 262 abnormalities, 113 (43.1%) were neurologic, 69 were gynecologic (26.3%), 36 (13.7%) urinary, 24 (9.2%) gastrointestinal and 20 (7.6%) musculoskeletal. Of the 262 incidental findings, 237 (90.5%) were level I, 24 (9.2%) were level II and 1 (0.4%) was level III. Our results suggest that although the vast majority of incidental maternal findings are benign, more significant findings are still encountered and should be expected. (orig.)

  4. Fetal MRI: incidental findings in the mother

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    Abdullah, Selwan B. [University of Maryland Medical Center, Diagnostic Radiology and Nuclear Medicine, Baltimore, MD (United States); University of Minnesota, Medical School, Minneapolis, MN (United States); Dietz, Kelly R.; Holm, Tara L. [University of Minnesota, Department of Radiology, Minneapolis, MN (United States)

    2016-11-15

    Fetal magnetic resonance imaging (MRI) is a routinely used tool in prenatal diagnosis; however, there is a lack of studies evaluating incidental findings observed in the mother. This study describes and quantifies incidental findings observed in the mother during fetal MRI. We reviewed all fetal MRI studies at the University of Minnesota Medical Center from February 2008 to September 2014. Two pediatric radiologists retrospectively conducted a consensus evaluation. The maternal findings were categorized into neurologic, gynecologic, urinary, gastrointestinal and musculoskeletal. Hydronephrosis consistent with the stage of pregnancy was recorded but was not included as an abnormal finding. Abnormal findings were classified into three groups, depending on their clinical significance: level I (low), level II (medium) and level III (high). We evaluated 332 pregnant patients with a mean age of 29.3 years and a mean gestational age of 29 weeks. Of these, 55.4% had at least 1 incidental finding, for a total of 262 incidental maternal findings. Of the 262 abnormalities, 113 (43.1%) were neurologic, 69 were gynecologic (26.3%), 36 (13.7%) urinary, 24 (9.2%) gastrointestinal and 20 (7.6%) musculoskeletal. Of the 262 incidental findings, 237 (90.5%) were level I, 24 (9.2%) were level II and 1 (0.4%) was level III. Our results suggest that although the vast majority of incidental maternal findings are benign, more significant findings are still encountered and should be expected. (orig.)

  5. Renal Myxoma, an Incidental Finding

    Directory of Open Access Journals (Sweden)

    Parth Thakker

    2017-07-01

    Full Text Available Myxomas are mesenchymal tumors commonly found in the heart and skin. Renal myxomas are rare, having only been documented 14 times. Our case is a 55-year-old woman who presented to our clinic after a right renal mass was incidentally found on CT. Evaluation with MRI showed a mass that appeared to arise from the supero-medial cortex of the right kidney. As the imaging was concerning for renal cell carcinoma, the patient underwent a partial nephrectomy. Microscopic examination showed a well-circumscribed mass with polygonal to spindle-shaped cells in a granular eosinophilic cytoplasm. Immunohistochemical staining for CD-10, Desmin, HMB-45, and Pankeratin were negative.

  6. Incidental Cardiac Findings on Thoracic Imaging.

    LENUS (Irish Health Repository)

    Kok, Hong Kuan

    2013-02-07

    The cardiac structures are well seen on nongated thoracic computed tomography studies in the investigation and follow-up of cardiopulmonary disease. A wide variety of findings can be incidentally picked up on careful evaluation of the pericardium, cardiac chambers, valves, and great vessels. Some of these findings may represent benign variants, whereas others may have more profound clinical importance. Furthermore, the expansion of interventional and surgical practice has led to the development and placement of new cardiac stents, implantable pacemaker devices, and prosthetic valves with which the practicing radiologist should be familiar. We present a collection of common incidental cardiac findings that can be readily identified on thoracic computed tomography studies and briefly discuss their clinical relevance.

  7. Clinically relevant incidental cardiovascular findings in CT examinations

    International Nuclear Information System (INIS)

    Voigt, P.; Fahnert, J.; Kahn, T.; Surov, A.; Schramm, D.; Bach, A.G.

    2017-01-01

    Incidental cardiovascular findings are a frequent phenomenon in computed tomography (CT) examinations. As the result of a dedicated PubMed search this article gives a systemic overview of the current literature on the most important incidental cardiovascular findings, their prevalence and clinical relevance. The majority of incidental cardiovascular findings are of only low clinical relevance; however, highly relevant incidental findings, such as aortic aneurysms, thromboses and thromboembolic events can also occasionally be found, especially in oncology patients. The scans from every CT examination should also be investigated for incidental findings as they can be of decisive importance for the further clinical management of patients, depending on their clinical relevance. (orig.) [de

  8. Incidental nuclear medicine findings affecting patient management

    International Nuclear Information System (INIS)

    Hector, B. M.

    2009-01-01

    Full text:A 62-year-old female patient presenting with flank pain and severe renal failure. Initial imaging modalities were unable to diagnose the cause, however, following a 18F fluorodeoxyglucose (18F-FDG) Positron Emission Tomography (PET) scan the patient was diagnosed and staged with Stage III cervical cancer. Stage III cervical cancer is usually treated by a combination of chemotherapy and radiotherapy. An incidental finding of a retroperitoneal urine leak on the PET scan and subsequent MAG-3 renal scan contraindicated the use of chemotherapy as a treatment and therefore severely affected patient management.

  9. Autosomal-dominant osteopetrosis: An incidental finding

    Directory of Open Access Journals (Sweden)

    Rajathi Maria

    2010-01-01

    Full Text Available Osteopetrosis is a descriptive term that refers to a group of rare, heritable disorders of the skeleton. Osteopetrotic conditions vary greatly in their presentation and severity, from just as an incidental finding on radiographs to causing life-threatening complications such as bone marrow suppression. It is caused by failure of osteoclast development and function. Osteopetrosis can be inherited as autosomal-recessive, autosomal-dominant or as X-linked traits, with the most severe forms being the autosomal-recessive ones. The severity of the disease is mild to moderate in the autosomal-dominant forms, with normal life expectancy. Diagnosis is largely based on clinical and radiographic evaluation. The present paper reports a case of autosomal-dominant osteopetrosis complicated by osteomyelitis with a short review of the condition.

  10. Incidental findings in youths volunteering for brain MRI research.

    Science.gov (United States)

    Gur, R E; Kaltman, D; Melhem, E R; Ruparel, K; Prabhakaran, K; Riley, M; Yodh, E; Hakonarson, H; Satterthwaite, T; Gur, R C

    2013-10-01

    MRIs are obtained in research in healthy and clinical populations, and incidental findings have been reported. Most studies have examined adults with variability in parameters of image acquisition and clinical measures available. We conducted a prospective study of youths and documented the frequency and concomitants of incidental findings. Youths (n = 1400) with an age range from 8-23 years were imaged on the same 3T scanner, with a standard acquisition protocol providing 1.0 mm(3) isotropic resolution of anatomic scans. All scans were reviewed by an experienced board-certified neuroradiologist and were categorized into 3 groups: 1) normal: no incidental findings; 2) coincidental: incidental finding(s) were noted, further reviewed with an experienced pediatric neuroradiologist, but were of no clinical significance; 3) incidental findings that on further review were considered to have potential clinical significance and participants were referred for appropriate clinical follow-up. Overall, 148 incidental findings (10.6% of sample) were noted, and of these, 12 required clinical follow-up. Incidental findings were not related to age. However, whites had a higher incidence of pineal cysts, and males had a higher incidence of cavum septum pellucidum, which was associated with psychosis-related symptoms. Incidental findings, moderated by race and sex, occur in approximately one-tenth of participants volunteering for pediatric research, with few requiring follow-up. The incidence supports a 2-tiered approach of neuroradiologic reading and clinical input to determine the potential significance of incidental findings detected on research MR imaging scans.

  11. Case Report on Septate Uterus: An Incidental Finding in a ...

    African Journals Online (AJOL)

    Case Report on Septate Uterus: An Incidental Finding in a Multiparous Woman who Had an Emergency Cesarean Section. ... Journal of Basic and Clinical Reproductive Sciences. Journal Home · ABOUT THIS JOURNAL · Advanced Search ...

  12. Incidental extra-mammary findings in breast MRI

    International Nuclear Information System (INIS)

    Alduk, A.M.; Prutki, M.; Stern-Padovan, R.

    2015-01-01

    Aim: To investigate the frequency, distribution, and nature of incidental extra-mammary findings detected with breast MRI. Materials and methods: Incidental findings were defined as unexpected lesions outside the breast, not previously known or suspected at the time of referral. Five hundred consecutive breast MRI studies performed from June 2010 to September 2012 were reviewed in this retrospective study for which the institutional review board granted approval and waived the requirement for informed consent. MRI findings were compared with subsequent diagnostic procedures in order to differentiate benign from malignant lesions. Results: One hundred and thirty-eight incidental findings were found in 107 of the 500 (21.4%) examined patients. The most common site was the liver (61/138; 44.2%), followed by the lung (24/138; 17.4%), mediastinum (22/138; 15.9%), pleural cavity (15/138; 10.9%), bone tissue (9/138; 6.5%), spleen (3/138; 2.2%), major pectoral muscle (3/138; 2.2%), and kidney (1/138; 0.7%). Twenty-five of the 138 (18.1%) incidental findings were confirmed to be malignant, whereas the remaining 113 (81.9%) were benign. Malignant findings were exclusively detected in patients with known breast carcinoma, whereas incidental findings in patients without a history of carcinoma were all benign. Twenty-five of 100 (24.8%) incidental findings among patients with history of breast cancer were malignant. Conclusion: Although many of incidental findings were benign, some were malignant, altering the diagnostic work-up, staging, and treatment. Therefore, it is important to assess the entire field of view carefully for abnormalities when reviewing breast MRI studies. - Highlights: • 500 consecutive breast MRI studies were retrospectively reviewed. • Incidental findings were found in 107/500 (21.4%) of examined patients. • Incidental extra-mammary findings on breast MRI are common. • Malignant findings were exclusively detected in patients with known breast

  13. Implication and Approach to Incidental Findings in Live Ultrasound Models

    Directory of Open Access Journals (Sweden)

    Shahram Lotfipour

    2011-05-01

    Full Text Available Introduction: Incidental findings during ultrasound examinations occur frequently with live models in training sessions. Because of the broad scope of training sessions available, the ethics and guidelines of dealing with incidental findings in live models need to be discussed. Methods: We provide a case of an endovaginal ultrasound that had significant unexpected findings. Results: This report demonstrates an important finding uncovered during an endovaginal modeling session. Conclusion: Models should be notified beforehand of the possibility of an incidental finding, informed about it, made aware of potential associated costs, referred to another physician for follow-up, and provided a copy of the scans. A secure copy of the ultrasound scan should be stored for future reference. [West J Emerg Med. 2011;12(4:472–474.

  14. Patients' views on incidental findings from clinical exome sequencing

    Directory of Open Access Journals (Sweden)

    Kristin E. Clift

    2015-03-01

    Full Text Available This article characterizes the opinions of patients and family members of patients undergoing clinical genomic-based testing regarding the return of incidental findings from these tests. Over sixteen months, we conducted 55 in-depth interviews with individuals to explore their preferences regarding which types of results they would like returned to them. Responses indicate a diversity of attitudes toward the return of incidental findings and a diversity of justifications for those attitudes. The majority of participants also described an imperative to include the patient in deciding which results to return rather than having universal, predetermined rules governing results disclosure. The results demonstrate the importance of a patient centered-approach to returning incidental findings.

  15. Incidental findings in musculoskeletal radiology; Zufallsbefunde in der muskuloskeletalen Radiologie

    Energy Technology Data Exchange (ETDEWEB)

    Wuennemann, F.; Rehnitz, C.; Weber, M.A. [Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie, Heidelberg (Germany)

    2017-04-15

    Increasing numbers of conventional X-rays, computed tomography and magnetic resonance imaging in the inpatient, outpatient and scientific routine leads to an increasing number of incidental findings. The correct interpretation of these incidental findings with respect to the relevance and the evaluation concerning further work-up is an important task of radiologists. Description of common incidental findings in musculoskeletal imaging and their clinical classification. A PubMed literature search was performed using the following terms: incidental findings, population-based imaging, musculoskeletal imaging, non-ossifying fibroma, enchondroma, osteodystrophia deformans, chondrosarcoma, fibrous dysplasia, simple bone cyst, unicameral bone cyst, solitary bone cyst, aneurysmal bone cyst, vertebral hemangioma, bone island, osteopoikilosis, Tarlov cyst and diffuse idiopathic skeletal hyperostosis (DISH). Incidental findings are observed in up to 40% of imaging procedures. In up to 6% these incidental findings involve the skeletal system. Common incidental findings are discussed and their clinical relevance is explained. (orig.) [German] Mit steigender Menge an konventionellen Roentgen- sowie CT- und MRT-Bildern im stationaeren, ambulanten und wissenschaftlichen Alltag steigt unweigerlich auch die Zahl der Zufallsbefunde. Die korrekte Einordnung bzgl. deren Relevanz, ob eine weitere Abklaerung notwendig ist oder nicht, stellt eine wichtige Aufgabe des Radiologen dar. Vorstellung haeufiger Zufallsbefunde des muskuloskeletalen Systems und deren klinische Einordnung. Pubmed-Literaturrecherche zu den Stichworten ''incidental findings'', ''population-based imaging'', ''musculoskeletal imaging'', ''non-ossifying fibroma'', ''enchondroma'', ''osteodysthrophia deformans'', ''chondrosarcoma'', ''fibrous dysplasia'', &apos

  16. Renal arterial aneurysm--an incidental finding at autopsy.

    Directory of Open Access Journals (Sweden)

    Vaideeswar P

    1998-01-01

    Full Text Available Herein we describe a rare case of saccular renal artery aneurysm seen as an incidental autopsy finding in an elderly, hypertensive female. The aneurysm was seen as a small exophytic mass with calcified wall and lumen occluded by recanalized thrombus.

  17. Incidental finding of hypertension and diminished femoral pulses ...

    African Journals Online (AJOL)

    2012-06-08

    Jun 8, 2012 ... Case Study: Incidental finding of hypertension and diminished femoral pulses. 168. Vol 55 No 2. S Afr Fam Pract 2013. Introduction. Coarctation of the aorta is ... Surgery of the aorta and its branches. Philadelphia: WB Saunders Company, 2000; p. 3-10. 2. Rao PS. Coarctation of the aorta. Curr Cardiol Rep.

  18. Incidental findings in chest X-rays; Zufallsbefunde im Roentgenthorax

    Energy Technology Data Exchange (ETDEWEB)

    Wielpuetz, M.O.; Kauczor, H.U. [Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie, Heidelberg (Germany); Universitaet Heidelberg, Translational Lung Research Center (TLRC), Deutsches Zentrum fuer Lungenforschung (DZL), Heidelberg (Germany); Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie mit Nuklearmedizin, Thoraxklinik, Heidelberg (Germany); Weckbach, S. [Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie, Heidelberg (Germany); Universitaet Heidelberg, Translational Lung Research Center (TLRC), Deutsches Zentrum fuer Lungenforschung (DZL), Heidelberg (Germany)

    2017-04-15

    Conventional projection radiography (chest x-ray) is one of the most frequently requested procedures in radiology. Even though chest x-ray imaging is frequently performed in asymptomatic patients for preoperative assessment, clinically relevant incidental findings are relatively scarce. This is due to the relatively low sensitivity of chest x-rays where few clinically relevant incidental findings are to be expected, as any detectable pathologies will as a rule already be clinically symptomatic. Recommendations from relevant societies for the management of incidental findings, apart from the clarification of incidental nodules, do not exist. This review article therefore describes the most frequent and typical incidental findings of lung parenchyma (apart from pulmonary nodules), mediastinal structures including the hilum of the lungs, pleura, chest wall and major vessels. Also described are those findings which can be diagnosed with sufficient certainty from chest x-rays so that further clarification is not necessary and those which must be further clarified by multislice imaging procedures or other techniques. (orig.) [German] Eine der haeufigsten Untersuchungen in der Radiologie ist die konventionelle Projektionsradiographie des Thorax (Roentgenthorax). Auch wenn projektionsradiographische Aufnahmen im Rahmen einer praeoperativen Abklaerung haeufig als orientierende Untersuchung angefertigt werden, sind - bedingt durch die relativ geringe Sensitivitaet des Roentgenthorax - wenig klinisch relevante Zufallsbefunde zu erwarten, da nachweisbare Pathologien in der Regel bereits auch klinisch apparent sind. Empfehlungen entsprechender Fachgesellschaften zu Zufallsbefunden im Roentgenthorax jenseits der Abklaerung von Rundherden liegen nicht vor. Die vorliegende Arbeit beleuchtet daher haeufige und typische Zufallsbefunde des Lungenparenchyms (ausser den Lungenrundherden), der mediastinalen Strukturen einschliesslich der Hili, der Pleura, der Thoraxwand sowie der

  19. Incidental MRI Findings in Patients with Impaired Cognitive Function

    International Nuclear Information System (INIS)

    Hwang, Yoon Joon

    2013-01-01

    This study aims to evaluate the incidental findings on brain MRI of patients with cognitive function impairments. We analyzed magnetic resonance (MR) findings of 236 patients with decreased cognitive function. MR protocols include conventional T2 weighted axial images, fluid attenuated inversion recovery axial images, T1 weighted coronal 3-dimensional magnetization-prepared rapid acquisition of gradient echo and diffusion tensor images. We retrospectively evaluated the signal changes that suggest acute/subacute infarction and space occupying lesions which show mass effect. Incidental MR findings were seen in 16 patients. Nine patients (3.8%) showed increased signal intensity on trace map of diffusion tensor images suggesting acute/subacute infarctions. Space occupying lesions were detected in 7 patients, and 3 lesions (1.27%) had mass effect and edema and were considered clinically significant lesions that diminish cognitive functions. Several incidental MR findings were detected in patients with decreased cognitive function, and the incidence of aucte/subacute infarctions were higher. Proper evaluations of MRI in patients with impaired cognitive functions will be helpful in early detection and management of ischemic lesions and space occupying lesions.

  20. Managing incidental findings in population based biobank research

    Directory of Open Access Journals (Sweden)

    Berge Solberg

    2012-04-01

    Full Text Available With the introduction of whole genome sequencing in medical research, the debate on how to handle incidental findings is becoming omnipresent. Much of the literature on the topic so far, seems to defend the researcher’s duty to inform, the participant’s right to know combined with a thorough informed consent in order to protect and secure high ethical standards in research. In this paper, we argue that this ethical response to incidental findings and whole genome sequencing is appropriate in a clinical context, in what we call therapeutic research. However, we further argue, that it is rather inappropriate in basic research, like the research going on in public health oriented population based biobanks. Our argument is based on two premises: First, in population based biobank research the duties and rights involved are radically different from a clinical based setting. Second, to introduce the ethical framework from the clinical setting into population based basic research, is not only wrong, but it may lead to unethical consequences. A Norwegian population based biobank and the research-ethical debate in Norway on the regulation of whole genome sequencing is used as an illustrative case to demonstrate the pitfalls when approaching the debate on incidental findings in population based biobank research.

  1. Incidental findings, genetic screening and the challenge of personalisation

    Directory of Open Access Journals (Sweden)

    Carlo Petrini

    2014-12-01

    Full Text Available Genetic tests frequently produce more information than is initially expected. Several documents have addressed this issue and offer suggestions regarding how this information should be managed and, in particular, concerning the expedience of revealing (or not revealing it to the persons concerned. While the approaches to the management of these incidental findings (IFs vary, it is usually recommended that the information be disclosed if there is confirmed clinical utility and the possibility of treatment or prevention. However, this leaves unsolved some fundamental issues such as the different ways of interpreting "clinical utility", countless sources of uncertainty and varying ways of defining the notion of "incidental". Guidelines and other reference documents can offer indications to those responsible for managing IFs but should not be allowed to relieve researchers and healthcare professionals of their responsibilities.

  2. Incidental Findings in Neuroimaging: Ethical and Medicolegal Considerations.

    Science.gov (United States)

    Leung, Lawrence

    2013-01-01

    With the rapid advances in neurosciences in the last three decades, there has been an exponential increase in the use of neuroimaging both in basic sciences and clinical research involving human subjects. During routine neuroimaging, incidental findings that are not part of the protocol or scope of research agenda can occur and they often pose a challenge as to how they should be handled to abide by the medicolegal principles of research ethics. This paper reviews the issue from various ethical (do no harm, general duty to rescue, and mutual benefits and owing) and medicolegal perspectives (legal liability, fiduciary duties, Law of Tort, and Law of Contract) with a suggested protocol of approach.

  3. Incidental finding of cutaneous meningeal heterotopia in aplasia cutis congenita.

    Science.gov (United States)

    Kenyon, Katharine; Zedek, Daniel; Sayed, Christopher

    2016-07-01

    Aplasia cutis congenita and cutaneous meningeal heterotopia are both rare congenital conditions that most commonly occur on the scalp and may appear clinically and histologically similar. A subtype of aplasia cutis congenita, membranous aplasia cutis congenita, and cutaneous meningeal heterotopia are both proposed to result from neural tube closure errors. However, neither non-membranous nor membranous aplasia cutis congenita are known to occur together with cutaneous meningeal heterotopia in the same lesion. We report the incidental finding of cutaneous meningeal heterotopia within a lesion of aplasia cutis congenita. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Managing incidental findings in human subjects research: analysis and recommendations.

    Science.gov (United States)

    Wolf, Susan M; Lawrenz, Frances P; Nelson, Charles A; Kahn, Jeffrey P; Cho, Mildred K; Clayton, Ellen Wright; Fletcher, Joel G; Georgieff, Michael K; Hammerschmidt, Dale; Hudson, Kathy; Illes, Judy; Kapur, Vivek; Keane, Moira A; Koenig, Barbara A; Leroy, Bonnie S; McFarland, Elizabeth G; Paradise, Jordan; Parker, Lisa S; Terry, Sharon F; Van Ness, Brian; Wilfond, Benjamin S

    2008-01-01

    No consensus yet exists on how to handle incidental findings (IFs) in human subjects research. Yet empirical studies document IFs in a wide range of research studies, where IFs are findings beyond the aims of the study that are of potential health or reproductive importance to the individual research participant. This paper reports recommendations of a two-year project group funded by NIH to study how to manage IFs in genetic and genomic research, as well as imaging research. We conclude that researchers have an obligation to address the possibility of discovering IFs in their protocol and communications with the IRB, and in their consent forms and communications with research participants. Researchers should establish a pathway for handling IFs and communicate that to the IRB and research participants. We recommend a pathway and categorize IFs into those that must be disclosed to research participants, those that may be disclosed, and those that should not be disclosed.

  5. Incidental Findings in Neuroimaging: Ethical and Medicolegal Considerations

    Directory of Open Access Journals (Sweden)

    Lawrence Leung

    2013-01-01

    Full Text Available With the rapid advances in neurosciences in the last three decades, there has been an exponential increase in the use of neuroimaging both in basic sciences and clinical research involving human subjects. During routine neuroimaging, incidental findings that are not part of the protocol or scope of research agenda can occur and they often pose a challenge as to how they should be handled to abide by the medicolegal principles of research ethics. This paper reviews the issue from various ethical (do no harm, general duty to rescue, and mutual benefits and owing and medicolegal perspectives (legal liability, fiduciary duties, Law of Tort, and Law of Contract with a suggested protocol of approach.

  6. Spatial resolution and chest nodule detection: an interesting incidental finding

    Science.gov (United States)

    Toomey, R. J.; McEntee, M. F.; Ryan, J. T.; Evanoff, M. G.; Hayes, A.; Brennan, P. C.

    2010-02-01

    This study reports an incidental finding from a larger work. It examines the relationship between spatial resolution and nodule detection for chest radiographs. Twelve examining radiologists with the American Board of Radiology read thirty chest radiographs in two conditions - full (1500 × 1500 pixel) resolution, and 300 × 300 pixel resolution linearly interpolated to 1500 × 1500 pixels. All images were surrounded by a 10-pixel sharp grey border to aid in focussing the observer's eye when viewing the comparatively unsharp interpolated images. Fifteen of the images contained a single simulated pulmonary nodule. Observers were asked to rate their confidence that a nodule was present on each radiograph on a scale of 1 (least confidence, certain no lesion is present) to 6 (most confidence, certain a lesion was present). All other abnormalities were to be ignored. No windowing, levelling or magnification of the images was permitted and viewing distance was constrained to approximately 70cm. Images were displayed on a 3 megapixel greyscale monitor. Receiver operating characteristic (ROC) analysis was applied to the results of the readings using the Dorfman-Berbaum-Metz multiplereader, multiple-case method. No statistically significant differences were found with either readers and cases treated as random or with cases treated as fixed. Low spatial frequency information appears to be sufficient for the detection of chest lesion of the type used in this study.

  7. Management of intracranial incidental findings on brain MRI; Management intrakranieller Zufallsbefunde in der MRT-Bildgebung

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    Langner, S.; Buelow, R.; Kirsch, M. [University Medicine Greifswald (Germany). Inst. for Diagnostic Radiology and Neuroradiology; Fleck, S. [University Medicine Greifswald (Germany). Dept. of Neurosurgery; Angermaier, A. [University Medicine Greifswald (Germany). Dept. of Neurology

    2016-12-15

    The wider use of MRI for imaging of the head in both research and clinical practice has led to an increasing number of intracranial incidental findings. Most of these findings have no immediate medical consequences. Nevertheless, knowledge of common intracranial incidental findings and their clinical relevance is necessary to adequately discuss the findings with the patient. Based on the author's experiences from a large population-based study, the most common incidental MR findings in the brain will be presented, discussing their clinical relevance and giving recommendations for management according to the current literature and guidelines.

  8. Prevalence and clinical significance of extravascular incidental findings in patients undergoing CT cervico-cerebral angiography

    International Nuclear Information System (INIS)

    Crockett, Matthew Thomas; Murphy, Blathnaid; Smith, Jennifer; Kavanagh, Eoin Carl

    2015-01-01

    Highlights: • CT cervico-cerebral angiography (CTCCA) is a commonly performed study for assessment of vascular pathologies of head and neck. • This study assessed the prevalence, clinical significance and management of extravascular incidental findings detected on CTCCA. • This study demonstrated the presence of clinically significant incidental findings in 14% of patients undergoing CTCCA with 8% of these findings deemed to be highly significant. 19% of patients with highly clinically significant findings did not receive appropriate follow up. • A standardised method of reporting incidental findings, such as that used in this paper is suggested to aid radiologists and referring physicians in recording and communicating these findings. - Abstract: Introduction: CT cervico-cerebral angiography (CTCCA) is now the first line diagnostic imaging modality for the majority of vascular pathologies of the head and neck with diagnostic value comparable to or better than traditional angiographic techniques. The aim of this study was to assess the prevalence, clinical significance and management of extravascular incidental findings detected on CTCCA. Materials and methods: A retrospective review of the CTCCA reports of 302 consecutive patients from 2009 to 2013 was undertaken. Extravascular incidental findings were classified, according to an adaptation of the CT colonography data and reporting system (CRADS), as EV1–EV4. EV1 = no incidental findings, EV2 = clinically insignificant incidental finding, EV3 = incidental finding of intermediate clinical significance, EV4 = highly clinically significant finding. Follow up of the electronic medical records of patients with EV3 or EV4 findings was undertaken to determine subsequent management. Results: Potentially clinically significant findings were demonstrated in 14.2% of patients with 8.6% of patients having a highly clinically significant finding. 4 incidental findings were confirmed to be malignant lesions and 5

  9. Intracranial incidental findings on brain MR images in a pediatric neurology practice: a retrospective study.

    Science.gov (United States)

    Gupta, Surya N; Belay, Brook

    2008-01-15

    Previous studies have addressed the prevalence of incidental findings largely in healthy adult and pediatric populations. Our study aims to elucidate the prevalence of incidental findings in a pediatric neurology practice. We reviewed the charts of 1618 patients seen at a pediatric neurology practice at a tertiary care center from September 2003 to December 2005 for clinical data and incidental intracranial findings on brain magnetic resonance imaging reports. Incidental findings were divided into two categories: normal or abnormal variants. Clinical and demographic data were assessed for associations with incidental findings. From 1618 charts reviewed, only 666 patients (41% of all patients) had brain MRIs ordered. One-hundred and seventy-one (171) patients (25.7% of all patients; 95% CI: 22.6, 29.0) had incidental findings. Of these, 113 (17.0%; 95% CI: 14.1, 19.8) were classified as normal-variants and 58 (8.7%; 95% CI: 6.6, 10.9) were classified as abnormal. The nature of incidental findings was not related to age group, sex or clinical diagnosis (p=0.29, p=0.31 and p=0.69 respectively). Two patients (0.3%; 95% CI: approximately 0.0, 0.7) required neurosurgical referral. We report a high prevalence of and a low rate of referrals for incidental findings in comparison to previous studies. The present study may help guide management decisions and discussions with patients and families. Future studies should attempt to address issues of associations between primary or secondary diagnoses and intracranial incidental findings in a controlled, prospective fashion.

  10. Papillary Cystadenoma: An Incidental Finding in Tubal Ligation

    Directory of Open Access Journals (Sweden)

    Tabitha Lynn Ward

    2018-01-01

    Full Text Available von Hippel-Lindau disease (vHLD is a rare autosomal dominant disorder with multiple benign and malignant tumors of different organs. We report a papillary cystadenoma of the mesosalpinx found in close association with an adenomatoid tumor discovered incidentally following tubal ligation in a patient with vHLD.

  11. Incidental Findings in Imaging Research: Evaluating Incidence, Benefit and Burden

    Science.gov (United States)

    Orme, Nicholas M.; Fletcher, Joel G.; Siddiki, Hassan A.; Harmsen, W. Scott; O’Byrne, Megan M.; Port, John D.; Tremaine, William J.; Pitot, Henry C.; McFarland, Beth; Robinson, Marguerite E.; Koenig, Barabara A.; King, Bernard F.; Wolf, Susan M.

    2013-01-01

    Context Little information exists concerning the frequency of clinically significant incidental findings (IFs) identified in the course of imaging research across a broad spectrum of imaging modalities and body regions. Objective To estimate the frequency with which research imaging IFs generate further clinical action, and the medical benefit/burden of identifying these IFs. Design, Setting, and Participants Retrospective review of subjects undergoing a research imaging exam that was interpreted by a radiologist for IFs in the first quarter of 2004, with 3-year clinical follow-up. An expert panel reviewed IFs generating clinical action to determine medical benefit/burden based on predefined criteria. Main Outcome Measures Frequency of (1) IFs that generated further clinical action by modality, body part, age, gender, and (2) IFs resulting in clear medical benefit or burden. Results 1376 patients underwent 1426 research imaging studies. 40% (567/1426) of exams had at least one IF (1055 total). Risk of an IF increased significantly by age (OR=1.5; [1.4–1.7=95% C.I.] per decade increase). Abdominopelvic CT generated more IFs than other exams (OR=18.9 compared with ultrasound; 9.2% with subsequent clinical action), with CT Thorax and MR brain next (OR=11.9 and 5.9; 2.8% and 2.2% with action, respectively). Overall 6.2% of exams (35/567) with an IF generated clinical action, resulting in clear medical benefit in 1.1% (6/567) and clear medical burden in 0.5% (3/567). In most instances, medical benefit/burden was unclear (4.6%; 26/567). Conclusions The frequency of IFs in imaging research exams varies significantly by imaging modality, body region and age. Research imaging studies at high risk for generating IFs can be identified. Routine evaluation of research images by radiologists may result in identification of IFs in a substantial number of cases and subsequent clinical action to address them in much smaller number. Such clinical action can result in medical

  12. Incidental dentomaxillofacial findings on cone beam computed tomography images of Iranian population

    Directory of Open Access Journals (Sweden)

    Leila Khojastepour

    2014-04-01

    Full Text Available BACKGROUND AND AIM: The present study aimed to assess the nature and prevalence of incidental findings in cone beam computed tomography (CBCT images of oral and maxillofacial patients. METHODS: In this cross-sectional study, 773 CBCT samples were retrieved from archives of a private oral and maxillofacial radiology center. Any findings that were not related to the reason of CBCT request was recorded in forms designed originally for this study. RESULTS: 475 patients out of 773 had at least one incidental finding. It composed about 60% of the patients. The largest frequency of incidental findings were cases of periapical lesions. (n = 189, followed by mucous thickening of maxillary sinus (n = 170, retained root (n = 32, impaction and 3rd molar (n = 26. Other incidental findings were torus (n = 25, dental anomalies (n = 13, vertical root fracture (n = 5, intra bony lesion and periapical pathosis (n = 4 and the lowest frequency was sialoliths (n = 1. CONCLUSION: About half of the subjects have had at least one incidental finding, so the precise review of the CBCT images seems to be necessary.

  13. LCA Cookbook

    DEFF Research Database (Denmark)

    Hauschild, Michael Z.; Bjørn, Anders

    2018-01-01

    The LCA cookbook presents the provisions and actions from the ILCD Handbook that are central in the performance of an LCA. The selection is intended to cover all those activities that an LCA practitioner needs to undertake in a typical process-LCA , and the presentation follows the normal progres...... progression of the LCA work according to the ISO framework. For explanation of the reasoning behind the actions, the reader is referred to the presentation of the methodological elements in Part 2 of the book....

  14. Clinical magnetic resonance imaging. Frequent incidental cerebral findings; Klinische Magnetresonanztomographie. Haeufige zerebrale Zufallsbefunde

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, A.; Ditter, P.; Schild, H.H.; Hattingen, E. [Universitaetsklinikum Bonn, Funktionseinheit Neuroradiologie der Klinik fuer Radiologie, Bonn (Germany); Weidauer, S. [St.-Katharinen-Krankenhaus, Neurologische Klinik, Frankfurt/M (Germany)

    2017-04-15

    The increasing use of magnetic resonance imaging (MRI) in clinical diagnostics means that patients and physicians are confronted more often with incidental findings. In the literature there are fluctuating data on the incidence of such findings and guidelines concerning the further procedure exist in only very few cases, such as incidental aneurysms and pituitary adenomas. The diagnostic and therapeutic implications which can be derived from incidental findings depend on multiple factors, such as anatomical location, patient age, comorbidity and patient wishes. For this reason it often makes sense to refer patients with incidental findings to an interdisciplinary neurological center at an early stage. In this review frequent incidental cerebral findings, epidemiological data, imaging criteria and, where possible, recommendations for the further procedure are shown. (orig.) [German] Durch den gehaeuften Einsatz der MRT in der zerebralen Diagnostik werden Arzt und Patienten in zunehmendem Masse mit Zufallsbefunden, auch Nebenbefunde genannt, konfrontiert. In der Literatur existieren sehr schwankende Angaben zur Haeufigkeit solcher Zufallsbefunde. Nur fuer einzelne dieser Befunde, wie z. B. das inzidentelle Aneurysma oder das Hypophysenadenom, existieren Leitlinien fuer das weitere Prozedere. Die aus einem Zufallsbefund abzuleitenden diagnostischen und therapeutischen Konsequenzen sind von vielen Faktoren, wie z. B. der anatomischen Lage, dem Patientenalter, den Komorbiditaeten und dem Patientenwunsch abhaengig. Daher ist es oft sinnvoll, den Patienten mit einem Zufallsbefund fruehzeitig in einem interdisziplinaeren Neurozentrum vorzustellen. In der vorliegenden Arbeit werden haeufige zerebrale Zufallsbefunde mit epidemiologischen Daten, bildgebenden Kriterien und - wenn moeglich - Empfehlungen bzgl. des weiteren Vorgehens gezeigt. (orig.)

  15. Clinically relevant incidental cardiovascular findings in CT examinations; Klinisch relevante kardiovaskulaere Zufallsbefunde bei CT-Untersuchungen

    Energy Technology Data Exchange (ETDEWEB)

    Voigt, P.; Fahnert, J.; Kahn, T.; Surov, A. [Universitaetsklinikum Leipzig, Klinik fuer Diagnostische und Interventionelle Radiologie, Leipzig (Germany); Schramm, D.; Bach, A.G. [Universitaetsklinikum Halle (Saale), Klinik fuer Radiologie, Halle (Germany)

    2017-04-15

    Incidental cardiovascular findings are a frequent phenomenon in computed tomography (CT) examinations. As the result of a dedicated PubMed search this article gives a systemic overview of the current literature on the most important incidental cardiovascular findings, their prevalence and clinical relevance. The majority of incidental cardiovascular findings are of only low clinical relevance; however, highly relevant incidental findings, such as aortic aneurysms, thromboses and thromboembolic events can also occasionally be found, especially in oncology patients. The scans from every CT examination should also be investigated for incidental findings as they can be of decisive importance for the further clinical management of patients, depending on their clinical relevance. (orig.) [German] Inzidentelle kardiovaskulaere Befunde sind ein haeufiges Phaenomen bei CT-Untersuchungen. Mit dieser Arbeit soll nach gezielter PubMed-Recherche ein systematischer Literaturueberblick ueber die wichtigsten kardiovaskulaeren Zufallsbefunde sowie deren Haeufigkeit und klinische Relevanz gegeben werden. Die Mehrzahl der inzidentellen kardiovaskulaeren Befunde sind klinisch nur von untergeordneter Bedeutung, allerdings werden immer wieder auch hochgradig relevante Zufallsbefunde wie beispielsweise Aortenaneurysmata oder - gerade bei onkologischen Patienten - Thrombosen und thrombembolische Ereignisse detektiert. Jede CT-Untersuchung sollte gezielt nach inzidentellen Befunden durchsucht werden, da diese je nach klinischer Relevanz von entscheidender Bedeutung fuer das weitere klinische Management des Patienten sein koennen. (orig.)

  16. Whole-body MRI in neurofibromatosis: incidental findings and prevalence of scoliosis

    International Nuclear Information System (INIS)

    Jaremko, Jacob L.; MacMahon, Peter J.; Torriani, Martin; Bredella, Miriam A.; Merker, Vanessa L.; Plotkin, Scott R.; Mautner, Victor F.

    2012-01-01

    To demonstrate incidental findings and scoliosis on whole-body MRI (WBMRI) in patients with neurofibromatosis type 1 and 2 (NF1 and NF2, respectively), and schwannomatosis. Institutional review board approval and written informed consent were obtained for this prospective HIPAA-compliant study. A total of 247 subjects (141 with NF1, 55 with NF2, 51 with schwannomatosis; 132 women (53.5%); mean age, 41 years, range, 18-97 years) underwent WBMRI using coronal STIR (TR/TE: 4190/111 ms, TI: 150 ms) and T1-weighted images (TR/TE: 454/10 ms), 10-mm slice thickness, imaging time ∝40 min. Images were reviewed for the presence of incidental findings, outside of nerve sheath tumors. The presence of scoliosis was recorded and curve morphology was assessed and quantified. Incidental findings other than scoliosis were recorded in 104/247 (42%) patients, most often affecting the musculoskeletal system (65/247 patients, 26%). We found 16/247 (6.5%) significant incidental findings likely to affect clinical management, including avascular necrosis of bone in eight patients (five with NF2), eight insufficiency fractures, and four non-neurogenic neoplasms (Hodgkin's lymphoma, liposarcoma, dermoid cyst, large uterine myoma requiring excision). Scoliosis was seen in 50/247 patients (20%), including 8/55 with NF2 (15%) and 11/51 with schwannomatosis (22%). Incidental findings in the neurofibromatoses frequently involve the skeleton. Given the relatively high incidence of unsuspected osteonecrosis and stress fractures, close attention to the skeleton on WBMRI is advised. In addition, knowledge of common incidental findings can help clinicians prepare patients who undergo WBMRI for potential unexpected findings. (orig.)

  17. Whole-body MRI in neurofibromatosis: incidental findings and prevalence of scoliosis

    Energy Technology Data Exchange (ETDEWEB)

    Jaremko, Jacob L.; MacMahon, Peter J.; Torriani, Martin; Bredella, Miriam A. [Massachusetts General Hospital and Harvard Medical School, Musculoskeletal Imaging and Intervention, Department of Radiology, Boston, MA (United States); Merker, Vanessa L.; Plotkin, Scott R. [Massachusetts General Hospital, Department of Neurology and Cancer Center, Boston, MA (United States); Mautner, Victor F. [University Medical Center Hamburg-Eppendorf, Department of Neurology, Hamburg (Germany)

    2012-08-15

    To demonstrate incidental findings and scoliosis on whole-body MRI (WBMRI) in patients with neurofibromatosis type 1 and 2 (NF1 and NF2, respectively), and schwannomatosis. Institutional review board approval and written informed consent were obtained for this prospective HIPAA-compliant study. A total of 247 subjects (141 with NF1, 55 with NF2, 51 with schwannomatosis; 132 women (53.5%); mean age, 41 years, range, 18-97 years) underwent WBMRI using coronal STIR (TR/TE: 4190/111 ms, TI: 150 ms) and T1-weighted images (TR/TE: 454/10 ms), 10-mm slice thickness, imaging time {proportional_to}40 min. Images were reviewed for the presence of incidental findings, outside of nerve sheath tumors. The presence of scoliosis was recorded and curve morphology was assessed and quantified. Incidental findings other than scoliosis were recorded in 104/247 (42%) patients, most often affecting the musculoskeletal system (65/247 patients, 26%). We found 16/247 (6.5%) significant incidental findings likely to affect clinical management, including avascular necrosis of bone in eight patients (five with NF2), eight insufficiency fractures, and four non-neurogenic neoplasms (Hodgkin's lymphoma, liposarcoma, dermoid cyst, large uterine myoma requiring excision). Scoliosis was seen in 50/247 patients (20%), including 8/55 with NF2 (15%) and 11/51 with schwannomatosis (22%). Incidental findings in the neurofibromatoses frequently involve the skeleton. Given the relatively high incidence of unsuspected osteonecrosis and stress fractures, close attention to the skeleton on WBMRI is advised. In addition, knowledge of common incidental findings can help clinicians prepare patients who undergo WBMRI for potential unexpected findings. (orig.)

  18. Renal lymphangiectasia: incidental finding at multislice computed tomography and literature review

    Energy Technology Data Exchange (ETDEWEB)

    Vasconcelos, Rodrigo Abdalla de; Pereira, Emanuelle Santiago [Hospital de Base do Distrito Federal (HBDF), Brasilia, DF (Brazil); Bauab Junior, Tufik [Instituto de Radiodiagnostico Rio Preto - Ultra-X and Hospital de Base de Faculdade de Medicina de Sao Jose do Rio Preto (Famerp), Sao Jose do Rio Preto, SP (Brazil); Valente, Rodolfo Silva [Hospital Universitario de Brasilia (HUB), Brasilia, DF (Brazil)

    2012-05-15

    Renal lymphangiectasia is a rare condition characterized by parapyelic and perirenal fluid collections, which may progress from asymptomatic condition to chronic renal failure. The present report describes a case of incidental computed tomography finding of bilateral lymphangiectasia in an asymptomatic patient, as well as the main imaging findings with a comprehensive literature review. (author)

  19. Incidental findings on MRI scans of patients presenting with audiovestibular symptoms.

    Science.gov (United States)

    Papanikolaou, Vasileios; Khan, Mohammad H; Keogh, Ivan J

    2010-06-07

    The evaluation of patients presenting with audiovestibular symptoms usually includes MRI of the internal auditory meatus, the cerebellopontine angle and the brain. A significant percentage of these scans will present unexpected, incidental findings, which could have important clinical significance. To determine the frequency and clinical significance of incidental findings on MRI scans of patients with audiovestibular symptoms. A retrospective analysis of 200 serial MRI scans. Gender distribution: equal. Age range: 17-82 years. One-hundred and four scans (52%) were normal and 1 scan (0.5%) demonstrated a unilateral vestibular schwannoma. Ninety-five scans (47.5%) demonstrated incidental findings. Sixty-six of these (33%) were considered of ishaemic origin and did not require further action. Five (2.5%) scans demonstrated significant findings which warranted appropriate referral; Two Gliomas (1%), 2 cases of extensive White Matter Lesions (1%), 1 lipoma (0.5%). The remaining scans demonstrated various other findings. Investigation of patients with audiovestibular symptoms with MRI scans revealed incidental findings in a significant percentage (47.5%). The majority of these findings were benign warranting no further action and only 2.5% required further referral. It is the responsibility of the referring Otolaryngologist to be aware of these findings, to be able to assess their significance, to inform the patient and if needed to refer for further evaluation.

  20. Incidental findings on cone beam computed tomography scans in cleft lip and palate patients

    NARCIS (Netherlands)

    Kuijpers, Mette A. R.; Pazera, Andrzej; Admiraal, Ronald J.; Berge, Stefaan J.; Vissink, Arjan; Pazera, Pawel

    Cone beam computed tomography (CBCT) is frequently used in treatment planning for alveolar bone grafting (ABG) and orthognathic surgery in patients with cleft lip and palate (CLP). CBCT images may depict coincident findings. The aim of this study was to assess the prevalence of incidental findings

  1. System-Level Process Change Improves Communication and Follow-Up for Emergency Department Patients With Incidental Radiology Findings.

    Science.gov (United States)

    Baccei, Steven J; Chinai, Sneha A; Reznek, Martin; Henderson, Scott; Reynolds, Kevin; Brush, D Eric

    2018-04-01

    The appropriate communication and management of incidental findings on emergency department (ED) radiology studies is an important component of patient safety. Guidelines have been issued by the ACR and other medical associations that best define incidental findings across various modalities and imaging studies. However, there are few examples of health care facilities designing ways to manage incidental findings. Our institution aimed to improve communication and follow-up of incidental radiology findings in ED patients through the collaborative development and implementation of system-level process changes including a standardized loop-closure method. We assembled a multidisciplinary team to address the nature of these incidental findings and designed new workflows and operational pathways for both radiology and ED staff to properly communicate incidental findings. Our results are based on all incidental findings received and acknowledged between November 1, 2016, and May 30, 2017. The total number of incidental findings discovered was 1,409. Our systematic compliance fluctuated between 45% and 95% initially after implementation. However, after overcoming various challenges through optimization, our system reached a compliance rate of 93% to 95%. Through the implementation of our new, standardized communication system, a high degree of compliance with loop closure for ED incidental radiology findings was achieved at our institution. Copyright © 2017 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  2. Incidental benign parotid lesions on FDG-PET: prevalence and clinico-pathologic findings

    International Nuclear Information System (INIS)

    Lim, Il Han; Lee, Won Woo; Chung, Jin Haeng; Park, So Yeon; Kim, Sang Hee; Kim, Yu Kyeong; Kim, Sang Eun

    2007-01-01

    Incidental parotid lesions on F-18 FDG-PET can mimic distant metastasis of underlying malignancy. The prevalence and the clinico-pathologic findings of PET positive parotid lesions have not been known. We investigated how often incidental parotid lesions are found on clinical FDG-PET studies and what the clinico-pathologic characteristics of those parotid lesions are in the present study. We retrospectively reviewed 3,344 cases of FDG-PET which had been obtained in our hospital from May 2003 to Dec 2006. The indications of FDG-PET were: evaluation of known/suspected cancer (n = 3,212) or screening of cancer in healthy subjects (n = 132). Incidental parotid lesion on FDG-PET was defined as an un-expected FDG uptake in one of parotid glands which was not primary target lesion of current FDG/PET. FDG uptake was represented by maximum standardized uptake value (maxSUV). Final diagnosis was made by pathologic analysis or clinical follow-up assessment. Fifteen (0.45% = 15/3,344) incidental parotid lesions were found and they were all benign lesions. The maxSUV ranged from 1.7 to 8.6 (mean ± s.d. = 3.7 ± 1.9). Final diagnoses of the incidental parotid lesions were; Warthin's tumor (n = 2), pleomorphic adenoma (n = 1), other un-specified benign lesion (n 1), and benign lesions under bases of imaging studies (n = 3) and of clinical follow-up (n = 8). All of incidentally found parotid lesions in clinical FDG-PET studies were confirmed as benign lesions with prevalence of 0.45%. Close follow up using PET or CT might be a reasonable approach for determining the nature of incidentally found parotid lesions

  3. LCA Applications

    DEFF Research Database (Denmark)

    Owsianiak, Mikołaj; Bjørn, Anders; Laurent, Alexis

    2018-01-01

    The chapter gives examples of applications of LCA by the central societal actors in government, industry and citizens, and discusses major motivations and challenges for the use of LCA to support science-based decision-making from their respective perspectives. We highlight applications of LCA...... environmental impacts of products and systems and support decisions around production and consumption and highlights factors that prevent its even more widespread application....

  4. LCA History

    DEFF Research Database (Denmark)

    Bjørn, Anders; Owsianiak, Mikołaj; Molin, Christine

    2018-01-01

    The idea of LCA was conceived in the 1960s when environmental degradation and in particular the limited access to resources started becoming a concern. This chapter gives a brief summary of the history of LCA since then with a focus on the fields of methodological development, application...

  5. Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?

    Directory of Open Access Journals (Sweden)

    Tirthankar Gayen

    2014-01-01

    Full Text Available Pseudoxanthoma elasticum (PXE is an inherited disorder characterized by generalized fragmentation and progressive calcification of elastic tissue. We report two sporadic cases of PXE, both of whom presented with asymptomatic yellowish papules over the flexural sites for cosmetic reasons. Histopathological findings on hematoxylin and eosin and Verhoeff-Van Gieson (VVG staining were classical of PXE. In addition to this, renal calcification was documented on plain radiography of kidneys, ureters, and bladder (KUB in both the cases. Paucity of literature describing the association of nephrocalcinosis with PXE prompted the present report.

  6. Prevalence of incidental findings on magnetic resonance imaging: Cuban project to map the human brain

    International Nuclear Information System (INIS)

    Hernandez Gonzalez, Gertrudis de los Angeles; Alvarez Sanchez, Marilet; Jordan Gonzalez, Jose

    2010-01-01

    To determine the prevalence of incidental findings in healthy subjects of the Cuban Human Brain Mapping Project sample, it was performed a retrospective descriptive study of the magnetic resonance imaging (MRI) obtained from 394 healthy subjects that make up the sample of the project, between 2006-2007, with an age range of 18 to 68 years (mean 33,12), of which 269 (68,27 %) are male and 125 (31,73 %) are women. It was shown that 40,36 % had one or more anomaly in the magnetic resonance imaging (MRI). In total, the number of incidental findings was 188, 23,6 % of which were brain findings and 24,11 % were non-brain findings, among the latter, were the sinusopathy with 20,81 % and maxillary polyps with 3,30 %. The most prevalent brain findings were: intrasellar arachnoidocele, 11,93 %, followed by the prominence of the pituitary gland, 5,84 %, ventricular asymmetry, 1,77 % and bone defects, 1,02 %. Other brain abnormalities found with very low prevalence had no pathological significance, except for two cases with brain tumor, which were immediately sent to a specialist. Incidental findings in MRI are common in the general population (40,36 %), being the sinusopathy, and intrasellar arachnoidocele the most common findings. Asymptomatic individuals who have any type of structural abnormality provide invaluable information on the prevalence of these abnormalities in a presumably healthy population, which may be used as references for epidemiological studies

  7. Healed perivalvular abscess: Incidental finding on transthoracic echocardiography

    Directory of Open Access Journals (Sweden)

    Vishnu Datt

    2014-01-01

    Full Text Available A 36-year-old male patient presented with the complaints of palpitations and breathlessness. Preoperative transthoracic echocardiography (TTE revealed a bicuspid aortic valve; severe aortic regurgitation with dilated left ventricle (LV and mild LV systolic dysfunction (ejection fraction 50%. He was scheduled to undergo aortic valve replacement. History was not suggestive of infective endocarditis (IE. Preoperative TTE did not demonstrate any aortic perivalvular abscess. Intraoperative transesophageal echocardiography (TEE examination using the mid-esophageal (ME long-axis view, showed an abscess cavity affecting the aortic valve, which initially was assumed to be a dissection flap, but later confirmed to be an abscess cavity by color Doppler examination. The ME aortic valve short-axis view showed two abscesses; one was at the junction of the non-coronary and left coronary commissure and the other one above the right coronary cusp. Intraoperatively, these findings were confirmed by the surgeons. The case report demonstrates the superiority of TEE over TTE in diagnosing perivalvular abscesses.

  8. An incidental finding of myocardial uptake on HDP bone scan

    International Nuclear Information System (INIS)

    Smith, T.

    1998-01-01

    Full text: A 75 year old male referred with a history of wrist pain for a HDP bone scan(700Mbq) had dynamic and blood pool images. A posterior sweep and planar images were performed after 2 hours. The scan demonstrated a fracture of the left radial styloid, other degenerative arthritis and diffuse tracer uptake throughout the myocardium. The differential diagnoses included cardiac amyloid, myocardial infarction (MI) and calcific pericarditis. The patient, a non insulin dependent diabetic with previous MI in 1978 and hypertension had nocturnal dyspnoea and no chest pain. Chest X-ray was normal. ECG revealed old inferior infarct. Echocardiography showed mild hypokinesis of the inferior wall, low normal LV contractility, normal pericardium and no evidence of amyloid. A Rest (400Mbq) / Stress(1200Mbq) Sestamibi(MIBI) was performed to assess status of ischaemic heart disease (IHD). The patient experienced leg fatigue and shortness of breath but no chest pain. Rest ECG showed sinus bradycardia with ST/T wave changes. Stress ECG showed ST segment depression (0.5mm). Planar and SPECT studies showed reversible perfusion defects in the anterior wall and apex with a fixed inferolateral defect. Gated SPECT showed normal wall motion apart from the inferolateral infarct. The exact cause of the HDP uptake in the myocardium is unknown. The echo findings exclude amyloid or pericarditis. The MIBI study confirmed a small inferolateral infarct and myocardial ischaemia in the anterior wall and apex. The scan has affected patient management by diagnosing a fracture of the radial styloid and confirming previous infarction and myocardial ischaemia. An open view must be taken of the cardiac HDP uptake. The most likely diagnosis in this patient is silent IHD, which has been demonstrated in one other case known to us

  9. Freedom of Choice About Incidental Findings Can Frustrate Participants' True Preferences.

    Science.gov (United States)

    Viberg, Jennifer; Segerdahl, Pär; Langenskiöld, Sophie; Hansson, Mats G

    2016-03-01

    Ethicists, regulators and researchers have struggled with the question of whether incidental findings in genomics studies should be disclosed to participants. In the ethical debate, a general consensus is that disclosed information should benefit participants. However, there is no agreement that genetic information will benefit participants, rather it may cause problems such as anxiety. One could get past this disagreement about disclosure of incidental findings by letting participants express their preferences in the consent form. We argue that this freedom of choice is problematic. In transferring the decision to participants, it is assumed that participants will understand what they decide about and that they will express what they truly want. However, psychological findings about people's reaction to probabilities and risk have been shown to involve both cognitive and emotional challenges. People change their attitude to risk depending on what is at stake. Their mood affects judgments and choices, and they over- and underestimate probabilities depending on whether they are low or high. Moreover, different framing of the options can steer people to a specific choice. Although it seems attractive to let participants express their preferences to incidental findings in the consent form, it is uncertain if this choice enables people to express what they truly prefer. In order to better understand the participants' preferences, we argue that future empirical work needs to confront the participant with the complexity of the uncertainty and the trade-offs that are connected with the uncertain predictive value of genetic risk information. © 2015 John Wiley & Sons Ltd.

  10. Incidental findings in healthy control research subjects using whole-body MRI

    International Nuclear Information System (INIS)

    Morin, S.H.X.; Cobbold, J.F.L.; Lim, A.K.P.; Eliahoo, J.; Thomas, E.L.; Mehta, S.R.; Durighel, G.; Fitzpatrick, J.; Bell, J.D.

    2009-01-01

    Aim: Magnetic resonance imaging (MRI) is a powerful clinical tool used increasingly in the research setting. We aimed to assess the prevalence of incidental findings in a sequential cohort of healthy volunteers undergoing whole-body MRI as part of a normal control database for imaging research studies. Materials and methods: 148 healthy volunteers (median age 36 years, range 21-69 years; 63.5% males, 36.5% females) were enrolled into a prospective observational study at a single hospital-based MRI research unit in London, UK. Individuals with a clinical illness, treated or under investigation were excluded from the study. Results: 43 (29.1%) scans were abnormal with a total of 49 abnormalities detected. Of these, 20 abnormalities in 19 patients (12.8%) were of clinical significance. The prevalence of incidental findings increased significantly with both increasing age and body mass index (BMI). Obese subjects had a fivefold greater risk of having an incidental abnormality on MRI (OR 5.4, CI 2.1-14.0). Conclusions: This study showed that more than one quarter of healthy volunteers have MR-demonstrable abnormalities. There was an increased risk of such findings in obese patients. This has ethical and financial implications for future imaging research, particularly with respect to informed consent and follow-up of those with abnormalities detected during the course of imaging studies.

  11. Incidental enchondromas at knee magnetic resonance imaging: intraobserver and interobserver agreement and prevalence of imaging findings

    Directory of Open Access Journals (Sweden)

    Sandra Akemi Nakamura

    2013-06-01

    Full Text Available Objective To evaluate intra- and interobserver agreement in the identification of incidental enchondromas at knee magnetic resonance imaging, and to assess the prevalence of imaging findings. Materials and Methods Retrospective study reviewing 326 knee magnetic resonance images acquired in the period between November 2009 and September 2010. The images were independently and blindly analyzed by two specialists in musculoskeletal radiology, with the objective of identifying incidental enchondromas, presence of foci with signal similar to bone marrow and foci of signal absence suggestive of calcifications within the enchondromas. Inter- and intraobserver agreements were analyzed. Results Eleven lesions compatible with enchondromas (3.3% were identified. The interobserver agreement for the presence of enchondroma was high. Prevalence of foci of bone marrow signal inside the enchondromas was of 54.55%, and foci suggestive of calcification corresponded to 36.36%. The intraobserver agreement for foci of bone marrow signal in enchondromas was perfect, and interobserver agreement was high. Conclusion The prevalence of incidental enchondromas in the current study was compatible with data in the literature. Excellent agreement was observed in the identification of enchondromas and in the assessment of imaging findings. A higher prevalence of fat signal foci was observed as compared with signal absence suggestive of calcifications.

  12. Incidental findings are frequent in young healthy individuals undergoing magnetic resonance imaging in brain research imaging studies

    DEFF Research Database (Denmark)

    Hartwigsen, Gesa; Siebner, Hartwig R; Deuschl, Günther

    2010-01-01

    There is an ongoing debate about how to handle incidental findings (IF) detected in healthy individuals who participate in research-driven magnetic resonance imaging (MRI) studies. There are currently no established guidelines regarding their management....

  13. Incidental radiologic findings at breast cancer diagnosis and likelihood of disease recurrence.

    Science.gov (United States)

    Brothers, Joel M; Kidwell, Kelley M; Brown, Richard K J; Henry, N Lynn

    2016-01-01

    Despite guidelines recommending against its routine use, perioperative imaging for distant metastases is frequently performed in newly diagnosed breast cancer patients, uncovering incidental findings of uncertain significance. We assessed the clinical significance of incidental findings by determining if their presence is associated with disease recurrence. A retrospective review of staging imaging was performed in patients with stage II or III invasive breast cancer diagnosed during 2008-2009 at a large academic medical center. Data related to perioperative imaging and disease recurrence were abstracted from the medical record. Kaplan-Meier curves and Cox proportional hazards models were used to assess the association between incidental findings and time to disease recurrence. A total of 169 of 340 patients (49.7 %) underwent staging evaluation for distant metastases (CT chest, abdomen, pelvis, bone scan, and/or PET-CT). Of these, 146 (86.4 %) had at least one suspicious or indeterminate finding. Follow-up studies were performed in 73 (43.2 %) patients. Nineteen patients were diagnosed with metastatic disease at diagnosis, 18 of whom had stage III disease. In patients without metastatic disease at diagnosis, 32 later developed recurrence. Non-calcified pulmonary nodules were associated with shorter time to disease recurrence (hazard ratio 2.51, 95 % CI 1.13-5.57, p = 0.02). Imaging for distant metastases frequently reveals indeterminate findings, most of which are not associated with disease recurrence. The association between pulmonary nodules and recurrence warrants validation in an independent cohort. Overall, these findings support current guidelines recommending against routine extent of disease evaluation in patients with newly diagnosed stage II breast cancer.

  14. Incidental bone scan findings in oral cavity in patients with cancer

    International Nuclear Information System (INIS)

    Gutierrez G, Patricia; Salvatierra R, Guillermo; Garcia, Arlene; Morales, Rosanna; Cano, Roque; Ortiz L, Jesus; Sotelo R, Silvia; Bustamante, Cesar

    2007-01-01

    The main aim of the present work, done in the Nuclear medicine Center IPEN-INEN, was to identify as incidental findings, increased inflammatory uptake in oral cavity in routine bone scintigraphies for neoplasic diseases control. A descriptive and retrospective study was performed studying bone scans from patients with cancer, that came to the Nuclear Medicine Center in 2003 and revising records of those who had inflammatory uptake in the oral cavity. It is concluded that, in cancer patients these findings are underestimated. Prospective research should be needed in order to determine the frequency of inflammatory oral cavity pathology detected in bone scintigraphies. (author)

  15. Incidental finding of single coronary artery in a patient with alcoholic cardiomyopathy presenting as acute heart failure.

    Science.gov (United States)

    McNair, Patrick; Jones, Erica; Truong, Quynh; Singh, Harsimran

    Single coronary artery is a rare clinical finding. Diagnosis is typically made incidentally after the patient presents with symptoms and undergoes coronary angiography, coronary computed tomography angiography (CTA), or post-mortem during autopsy. Several high-risk features of anomalous coronary arteries have been described in the literature. Our paper describes a case of dilated alcoholic cardiomyopathy presenting as heart failure with diagnostic workup incidentally revealing single coronary artery. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Societal preferences for the return of incidental findings from clinical genomic sequencing: a discrete-choice experiment.

    Science.gov (United States)

    Regier, Dean A; Peacock, Stuart J; Pataky, Reka; van der Hoek, Kimberly; Jarvik, Gail P; Hoch, Jeffrey; Veenstra, David

    2015-04-07

    An important challenge with the application of next-generation sequencing technology is the possibility of uncovering incidental genomic findings. A paucity of evidence on personal utility for incidental findings has hindered clinical guidelines. Our objective was to estimate personal utility for complex information derived from incidental genomic findings. We used a discrete-choice experiment to evaluate participants' personal utility for the following attributes: disease penetrance, disease treatability, disease severity, carrier status and cost. Study participants were drawn from the Canadian public. We analyzed the data with a mixed logit model. In total, 1200 participants completed our questionnaire (available in English and French). Participants valued receiving information about high-penetrance disorders but expressed disutility for receiving information on low-penetrance disorders. The average willingness to pay was $445 (95% confidence interval [CI] $322-$567) to receive incidental findings in a scenario where clinicians returned information about high-penetrance, medically treatable disorders, but only 66% of participants (95% CI 63%-71%) indicated that they would choose to receive information in that scenario. On average, participants placed an important value ($725, 95% CI $600-$850) on having a choice about what type of findings they would receive, including receipt of information about high-penetrance, treatable disorders or receipt of information about high-penetrance disorders with or without available treatment. The predicted uptake of that scenario was 76% (95% CI 72%-79%). Most participants valued receiving incidental findings, but personal utility depended on the type of finding, and not all participants wanted to receive incidental results, regardless of the potential health implications. These results indicate that to maximize benefit, participant-level preferences should inform the decision about whether to return incidental findings. © 2015

  17. Organisational LCA

    DEFF Research Database (Denmark)

    Martínez-Blanco, Julia; Finkbeiner, Matthias

    2018-01-01

    environmental performance over time, supporting strategic decisions, and informing corporate sustainability reporting. Several initiatives are on the way for the LCA of organisations: the UNEP/SETAC Life Cycle Initiative published the ‘Guidance on organizational LCA’, using ISO/TS 14072 as a backbone; moreover......, when the unit of analysis and the system boundaries are defined. Also, the approach for data collection needs to be fixed. Organisational LCA is a compilation and evaluation of the inputs, outputs and potential environmental impacts of the activities associated with the organisation adopting a life...... cycle perspective. It includes not only the facilities of the organisation itself, but also the activities upstream and downstream the value chain. This methodology is capable of serving multiple goals at the same time, like identifying environmental hotspots throughout the value chain, tracking...

  18. MR imaging of the pelvis: a guide to incidental musculoskeletal findings for abdominal radiologists.

    Science.gov (United States)

    Gaetke-Udager, Kara; Girish, Gandikota; Kaza, Ravi K; Jacobson, Jon; Fessell, David; Morag, Yoav; Jamadar, David

    2014-08-01

    Occasionally patients who undergo magnetic resonance imaging for presumed pelvic disease demonstrate unexpected musculoskeletal imaging findings in the imaged field. Such incidental findings can be challenging to the abdominal radiologist, who may not be familiar with their appearance or know the appropriate diagnostic considerations. Findings can include both normal and abnormal bone marrow, osseous abnormalities such as Paget's disease, avascular necrosis, osteomyelitis, stress and insufficiency fractures, and athletic pubalgia, benign neoplasms such as enchondroma and bone island, malignant processes such as metastasis and chondrosarcoma, soft tissue processes such as abscess, nerve-related tumors, and chordoma, joint- and bursal-related processes such as sacroiliitis, iliopsoas bursitis, greater trochanteric pain syndrome, and labral tears, and iatrogenic processes such as bone graft or bone biopsy. Though not all-encompassing, this essay will help abdominal radiologists to identify and describe this variety of pelvic musculoskeletal conditions, understand key radiologic findings, and synthesize a differential diagnosis when appropriate.

  19. Prevalence of cartilaginous tumours as an incidental finding on MRI of the knee

    International Nuclear Information System (INIS)

    Stomp, Wouter; Reijnierse, Monique; Bloem, Johan L.; Kloppenburg, Margreet; Mutsert, Renee de; Heijer, Martin den; Bovee, Judith V.M.G.

    2015-01-01

    The purpose was to determine prevalence of enchondromas and atypical cartilaginous tumour/chondrosarcoma grade 1 (ACT/CS1) of the knee on MRI in a large cohort study, namely the Netherlands Epidemiology of Obesity (NEO) study. Participants aged 45 to 65 years were prospectively included, oversampling overweight and obese persons. Within a subgroup of participants, MRI of the right knee was performed and screened for incidental cartilaginous tumours, as defined by their characteristic location and appearance. Forty-nine cartilaginous tumours were observed in 44 out of 1285 participants (estimated population prevalence 2.8 %, 95 % CI 2.0-4.0 %). Mean largest tumour diameter was 12 mm (range 2-31 mm). Eight participants with a tumour larger than 20 mm or a tumour with aggressive features were referred to rule out low-grade chondrosarcoma. One was lost to follow-up, three had histologically proven ACT/CS1 and four had dynamic contrast MRI findings consistent with benign enchondroma. Incidental cartilaginous tumours were relatively common on knee MRI and may be regarded as a normal concurrent finding. However, more tumours than expected were ACT/CS1. Because further examination was performed only when suspicion of chondrosarcoma was high, the actual prevalence might be even higher. (orig.)

  20. Prevalence of cartilaginous tumours as an incidental finding on MRI of the knee

    Energy Technology Data Exchange (ETDEWEB)

    Stomp, Wouter; Reijnierse, Monique; Bloem, Johan L. [Leiden University Medical Center, Department of Radiology, Leiden (Netherlands); Kloppenburg, Margreet [Leiden University Medical Center, Department of Rheumatology, Leiden (Netherlands); Leiden University Medical Center, Department of Clinical Epidemiology, Leiden (Netherlands); Mutsert, Renee de; Heijer, Martin den [Leiden University Medical Center, Department of Clinical Epidemiology, Leiden (Netherlands); Bovee, Judith V.M.G. [Leiden University Medical Center, Department of Pathology, Leiden (Netherlands); Collaboration: NEO study group

    2015-12-15

    The purpose was to determine prevalence of enchondromas and atypical cartilaginous tumour/chondrosarcoma grade 1 (ACT/CS1) of the knee on MRI in a large cohort study, namely the Netherlands Epidemiology of Obesity (NEO) study. Participants aged 45 to 65 years were prospectively included, oversampling overweight and obese persons. Within a subgroup of participants, MRI of the right knee was performed and screened for incidental cartilaginous tumours, as defined by their characteristic location and appearance. Forty-nine cartilaginous tumours were observed in 44 out of 1285 participants (estimated population prevalence 2.8 %, 95 % CI 2.0-4.0 %). Mean largest tumour diameter was 12 mm (range 2-31 mm). Eight participants with a tumour larger than 20 mm or a tumour with aggressive features were referred to rule out low-grade chondrosarcoma. One was lost to follow-up, three had histologically proven ACT/CS1 and four had dynamic contrast MRI findings consistent with benign enchondroma. Incidental cartilaginous tumours were relatively common on knee MRI and may be regarded as a normal concurrent finding. However, more tumours than expected were ACT/CS1. Because further examination was performed only when suspicion of chondrosarcoma was high, the actual prevalence might be even higher. (orig.)

  1. Incidental finding of a left over guide wire on a positron emission tomography

    International Nuclear Information System (INIS)

    Yap, Kok Hooi; Lee, Phong Teck; Buch, Mamta; Rammohan, Kandadai Seshadri

    2012-01-01

    The Seldinger technique is commonly used cannulate vessels for radiographical procedures. Loss of a guide wire into the circulation is a rare and preventable complication. It is often noticed by chance during routine radiographs. However, there is a lack of reported cases of incidental fin dings of leftover guide wire on a PET scan. An intravascular foreign body should be retrieved as soon as the diagnosis is made, to prevent complications such as embolisation or vascular damage by fractured wires. Interventional radiology is the method of choice for retrieval. We report a rare case of the coincidental finding of a lost guide wire on a PET scan. A 37 year old man presented with psychotic episodes, thigh weakness, weight gain, increased appetite and leg cramps. He was subsequently diagnosed with cushing syndrome secondary to ectopic adrenocorticotropic secretion from a right lung tumour. He subsequently underwent a staging positron emission tomography (PET) scan. The lung tumour had no uptake on PET bit had increased activity uptake on octreotide scanning. These appearances were suggestive of with carcinoid tumour. The PET scan also revealed an incidental finding of a leftover guide wire used during peripheral inserted central catheter (PICC) recently. The wire extended from right atrium to inferior vena cava. It also showed a high uptake in the adrenal glands, indicating hyperplasia, which was most likely due to adrenocorticotropic hormone stimulation. He underwent a percutaneous wire retrieval via the right femoral vein in a cardiac catheterisation laboratory and was transferred to a thoracic surgical unit for lung tumor resection

  2. Incidental finding of a left over guide wire on a positron emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Yap, Kok Hooi; Lee, Phong Teck; Buch, Mamta; Rammohan, Kandadai Seshadri

    2012-12-15

    The Seldinger technique is commonly used cannulate vessels for radiographical procedures. Loss of a guide wire into the circulation is a rare and preventable complication. It is often noticed by chance during routine radiographs. However, there is a lack of reported cases of incidental fin dings of leftover guide wire on a PET scan. An intravascular foreign body should be retrieved as soon as the diagnosis is made, to prevent complications such as embolisation or vascular damage by fractured wires. Interventional radiology is the method of choice for retrieval. We report a rare case of the coincidental finding of a lost guide wire on a PET scan. A 37 year old man presented with psychotic episodes, thigh weakness, weight gain, increased appetite and leg cramps. He was subsequently diagnosed with cushing syndrome secondary to ectopic adrenocorticotropic secretion from a right lung tumour. He subsequently underwent a staging positron emission tomography (PET) scan. The lung tumour had no uptake on PET bit had increased activity uptake on octreotide scanning. These appearances were suggestive of with carcinoid tumour. The PET scan also revealed an incidental finding of a leftover guide wire used during peripheral inserted central catheter (PICC) recently. The wire extended from right atrium to inferior vena cava. It also showed a high uptake in the adrenal glands, indicating hyperplasia, which was most likely due to adrenocorticotropic hormone stimulation. He underwent a percutaneous wire retrieval via the right femoral vein in a cardiac catheterisation laboratory and was transferred to a thoracic surgical unit for lung tumor resection.

  3. Incidental finding of breast cancer during myocardial perfusion imaging - a case study

    International Nuclear Information System (INIS)

    Maglica, Deanna L.

    2009-01-01

    Full text: There are many incidences in Nuclear Medicine where incidental findings of pathologies other than those under investigation are found. This is mainly due to the non-specific biodistribution of the radiopharmaceuticals throughout the body. Sestamibi is one such agent that can be used for multi-imaging purposes, such as cardiac, parathyroid and carcinoma imaging. A female patient with a known history of cardiac disease presented to our department for a myocardial perfusion stress rest study. Dipryridamole was used instead of an exercise test due to leg pain and poor patient mobility. 450MBq of 99mTc- Sestamibi was injected into the patient during stress and a further IOOOMBq of 99mTc-Sestamibi during rest approximately three hours later. Post stress/rest images illustrated not only a small inferolateral infarct, but also an abnormal focus of increased activity in the right breast in the lower outer quadrant. Knowing 99mTc-Sestamibi to have a high affinity to carcinoma cells, the abnormal focal uptake was correctly diagnosed as a breast cancer malignancy. Breast cancer was confirmed on mammography and the patient underwent breast surgery, chemotherapy and radiation therapy. This case highlights the importance of thoroughly checking all cardiac SPECT 99mTc-Sestamibi cine images for incidental findings of other pathologies.

  4. Temporomandibular joint MR images: Incidental head and neck findings and pathologies.

    Science.gov (United States)

    Orhan, Kaan; Avsever, Hakan; Aksoy, Seçil; Seki, Umut; Bozkurt, Poyzan

    2017-10-17

    To report the number and frequency of incidental findings (IFs) detected during magnetic resonance (MR) imaging screening of the temporomandibular joint (TMJ) and to define related diseases. Bilateral TMJ MR images in the sagittal and coronal sections, from 518 patients with TMJ symptoms were evaluated retrospectively. Patients who were diagnosed with IFs were sent for consultation and clarification of the findings. Patient age, gender, IFs, locations, and diseases were classified and noted.  Results: Seventy-eight (15%) patients were diagnosed with 117 IFs. Of them, 43 were diagnosed with a single IF, and 35 were diagnosed with more than one IF. The most frequent locations were paranasal sinuses and mastoid air cells. The most frequent diseases were inflammatory and cystic lesions.  Discussion: While examining TMJ MR images, it is important to check for evidence of IFs or pathologies that may have mimicked signs and symptoms of TMJ disorders.

  5. Fat deposition in the urinary bladder wall: Incidental finding on abdominal computed tomography: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Park, Min Ho; Moon, Sung Kyoung; Ahn, Sung Eun; Park, Seong Jin; Lim, Joo Won; Lee, Dong Ho [Dept. of Radiology, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul (Korea, Republic of)

    2015-02-15

    In a computed tomography (CT) scan, fat deposition in the urinary bladder wall is seen as a linear hypoattenuating band surrounded by soft tissue density. It is uncommon, but is often seen in normal cases. However, there is no report of fat deposition in the urinary bladder wall in Korea. The authors encountered a 62-year-old male patient who showed an incidental hypoattenuating band in the urinary bladder wall on abdominal CT. The patient showed no clinical signs related to fat deposition in the urinary bladder wall. When the patient's previous abdominal CT was retrospectively reviewed, the same CT finding was seen. This linear hypoattenuating band within the urinary bladder wall should be considered as a normal CT finding, although it is uncommon.

  6. Return of individual research results and incidental findings in the clinical trials cooperative group setting.

    Science.gov (United States)

    Ferriere, Michael; Van Ness, Brian

    2012-04-01

    The National Cancer Institute (NCI)-funded cooperative group cancer clinical trial system develops experimental therapies and often collects samples from patients for correlative research. The cooperative group bank (CGB) system maintains biobanks with a current policy not to return research results to individuals. An online survey was created, and 10 directors of CGBs completed the surveys asking about understanding and attitudes in changing policies to consider return of incidental findings (IFs) and individual research results (IRRs) of health significance. The potential impact of the 10 consensus recommendations of Wolf et al. presented in this issue are examined. Reidentification of samples is often not problematic; however, changes to the current banking and clinical trial systems would require significant effort to fulfill an obligation of recontact of subjects. Additional resources, as well as a national advisory board would be required to standardize implementation.

  7. An incidental primary papillary carcinoma arising in a thyroglossal duct cyst: Report of a rare finding

    Directory of Open Access Journals (Sweden)

    Mohammad Jaseem Hassan

    2016-01-01

    Full Text Available The thyroglossal duct cysts (TGDCs are the most common congenital anomaly of the thyroid, usually manifested as painless midline neck mass. Malignancy is very rare and is reported in around 1% of cases as an incidental finding after histopathological evaluation of resected cyst. Papillary carcinoma is the most common carcinoma reported in TGDC. Here, we report a case of 17-year-old-female, who presented with a gradually increasing midline neck mass which moves with swallowing. On imaging a diagnosis of infected TGDC was made. The Sistrunk operation was done and a diagnosis of primary papillary carcinoma arising in a TGDC was rendered histopathologically. The contemporary appearance of papillary carcinoma thyroid was reported in about 20% cases of TGDC carcinoma, thus it is essential to differentiate primary papillary carcinoma arising in a TGDC from those of metastatic papillary carcinoma thyroid by strict diagnostic criteria.

  8. Tubular sigmoid duplication in an adult man: an interesting incidental finding.

    Science.gov (United States)

    Asour, Amani; Kim, Hyun-Kyung; Arya, Shobhit; Hepworth, Clive

    2017-11-12

    A 61-year-old man attended an outpatient colorectal clinic for a chronic, non-specific abdominal pain, associated with rectal bleeding. He underwent a number of investigations including a CT pneumocolon, which revealed an incidental finding of 20 cm of additional sigmoid colon. This case is interesting because tubular sigmoid duplication is an extremely unusual condition, rarely diagnosed in adults; only a few cases have been reported of this condition in the adult population. Our team chose to treat this patient conservatively, in order to avoid putting the patient at risk of an unnecessary surgery. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  9. Incidental Finding of Inferior Vena Cava Atresia Presenting with Deep Venous Thrombosis following Physical Exertion

    Directory of Open Access Journals (Sweden)

    Shalini Koppisetty

    2015-01-01

    Full Text Available Inferior vena cava atresia (IVCA is a rare but well described vascular anomaly. It is a rare risk factor for deep venous thrombosis (DVT, found in approximately 5% of cases of unprovoked lower extremity (LE DVT in patients <30 years of age. Affected population is in the early thirties, predominantly male, often with a history of major physical exertion and presents with extensive or bilateral DVTs. Patients with IVC anomalies usually develop compensatory circulation through the collateral veins with enlarged azygous/hemizygous veins. Despite the compensatory circulation, the venous drainage of the lower limbs is often insufficient leading to venous stasis and thrombosis. We describe a case of extensive and bilateral deep venous thrombosis following physical exertion in a thirty-six-year-old male patient with incidental finding of IVCA on imaging.

  10. Impact of incidental findings on integrated 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in patients with gastric cancer.

    Science.gov (United States)

    Tae, Chung Hyun; Lee, Jun Haeng; Choi, Joon Young; Min, Byung-Hoon; Rhee, Poong-Lyul; Kim, Jae J

    2015-03-01

    Since positron emission tomography/computed tomography (PET/CT) has been introduced, many incidental findings have been identified. The aim of this study was to assess the clinical significance of incidental findings on PET/CT in patients with gastric cancer. A total of 421 patients with gastric cancer underwent PET/CT for initial staging. Incidental findings on PET/CT were classified into five categories according to clinical significance--normal variant, benign, probably benign, probably malignant, and definitely malignant. We obtained information regarding follow-up examinations, additional visits, final diagnosis of incidental findings and short-term medical costs for further evaluation. Eight hundred eighty-two incidental findings were detected in 386 (91.7%) patients. Of 274 incidental findings classified as probably benign, probably malignant or definitely malignant, 130 required one or more additional investigations. Finally, 12 (9.2%) were proved to be associated with second primary malignancy or metastasis of gastric cancer. One hundred twenty-nine additional outpatient visits and 10 additional hospitalizations were needed for evaluating the incidental findings. The treatment strategy for gastric cancer was changed in one patient. The estimated cost of additional investigations was $US283 (95% CI: $US248-$US311) per patient. Incidental findings on PET/CT were common. Although the incidental findings were suspicious of malignancy, most were benign with high costs for additional investigations. © 2015 Wiley Publishing Asia Pty Ltd.

  11. Prevalence of incidental or unexpected findings on low-dose CT performed during routine SPECT/CT nuclear medicine studies

    International Nuclear Information System (INIS)

    Yap, Kelvin Kwok-Ho; Sutherland, Tom; Shafik-Eid, Raymond; Taubman, Kim; Schlicht, Stephen; Ramaseshan, Ganeshan

    2015-01-01

    In nuclear medicine, single-photon-emission computed tomography (SPECT) is often combined with ‘simultaneous’ low-dose CT (LDCT) to provide complementary anatomical and functional correlation. As a consequence, numerous incidental and unexpected findings may be detected on LDCT. Recognition of these findings and appropriate determination of their relevance can add to the utility of SPECT/CT. We aimed to evaluate the prevalence and categorise the relevance of incidental and unexpected findings on LDCT scans performed as part of routine SPECT/CT studies. All available LDCT scans performed as part of SPECT/CT studies at St. Vincent's Hospital Melbourne in the year 2013 were retrospectively reviewed. Two qualified radiologists independently reviewed the studies and any previous available imaging and categorised any detected incidental findings. A total of 2447 LDCT studies were reviewed. The relevance of the findings was classified according to a modified version of a scale used in the Colonography Reporting and Data System: E1 = normal or normal variant (28.0%); E2 = clinically unimportant (63.5%); E3 = likely unimportant or incompletely characterised (6.2%); E4 = potentially important (2.5%). Imaging specialists need to be cognisant of incidental and unexpected findings present on LDCT studies performed as part of SPECT/CT. Appropriate categorisation of findings and communication of potentially important findings to referring clinicians should form part of routine practice. The overall prevalence of potentially significant incidental and unexpected findings in our series was 8.7% (E3, 6.2%; E4, 2.5%) and was comparable to rates in other published imaging series.

  12. An incidental case of biliary fascioliasis with subtle clinical findings: US and MRCP findings

    International Nuclear Information System (INIS)

    Önder, Hakan; Ekici, Faysal; Adin, Emin; Kuday, Suzan; Gümüş, Hatice; Bilici, Aslan

    2013-01-01

    Fascioliasis is a disease caused by the trematode Fasciola hepatica. Cholangitis is a common clinical manifestation. Although fascioliasis may show various radiological and clinical features, cases without biliary dilatation are rare. We present unique ultrasound (US) and magnetic resonance cholangiopancreatography (MRCP) findings of a biliary fascioliasis case which doesn’t have biliary obstruction or cholestasis. Radiologically, curvilinear parasites compatible with juvenile and mature Fasciola hepatica within the gallbladder and common bile duct were found. The parasites appear as bright echogenic structures with no acoustic shadow on US and hypo-intense curvilinear lesions on T2 weighted MRCP images. Imaging studies may significantly contribute to the diagnosis of patients with subtle clinical and laboratory findings, particularly in endemic regions

  13. Description and pilot results from a novel method for evaluating return of incidental findings from next-generation sequencing technologies.

    Science.gov (United States)

    Goddard, Katrina A B; Whitlock, Evelyn P; Berg, Jonathan S; Williams, Marc S; Webber, Elizabeth M; Webster, Jennifer A; Lin, Jennifer S; Schrader, Kasmintan A; Campos-Outcalt, Doug; Offit, Kenneth; Feigelson, Heather Spencer; Hollombe, Celine

    2013-09-01

    The aim of this study was to develop, operationalize, and pilot test a transparent, reproducible, and evidence-informed method to determine when to report incidental findings from next-generation sequencing technologies. Using evidence-based principles, we proposed a three-stage process. Stage I "rules out" incidental findings below a minimal threshold of evidence and is evaluated using inter-rater agreement and comparison with an expert-based approach. Stage II documents criteria for clinical actionability using a standardized approach to allow experts to consistently consider and recommend whether results should be routinely reported (stage III). We used expert opinion to determine the face validity of stages II and III using three case studies. We evaluated the time and effort for stages I and II. For stage I, we assessed 99 conditions and found high inter-rater agreement (89%), and strong agreement with a separate expert-based method. Case studies for familial adenomatous polyposis, hereditary hemochromatosis, and α1-antitrypsin deficiency were all recommended for routine reporting as incidental findings. The method requires definition of clinically actionable incidental findings and provide documentation and pilot testing of a feasible method that is scalable to the whole genome.

  14. Informed consent for exome sequencing research in families with genetic disease: the emerging issue of incidental findings.

    Science.gov (United States)

    Bergner, Amanda L; Bollinger, Juli; Raraigh, Karen S; Tichnell, Crystal; Murray, Brittney; Blout, Carrie Lynn; Telegrafi, Aida Bytyci; James, Cynthia A

    2014-11-01

    Genomic sequencing technology is increasingly used in genetic research. Studies of informed consent for exome and genome sequencing (ES/GS) research have largely involved hypothetical scenarios or healthy individuals enrolling in population-based studies. Studies have yet to explore the consent experiences of adults with inherited disease. We conducted a qualitative interview study of 15 adults recently enrolled in a large-scale ES/GS study (11 affected adults, four parents of affected children). Our study had two goals: (1) to explore three theoretical barriers to consent for ES/GS research (interpretive/technical complexity, possibility of incidental findings, and risks of loss of privacy); and (2) to explore how interviewees experienced the consent process. Interviewees could articulate study goals and processes, describe incidental findings, discuss risks of privacy loss, and reflect on their consent experience. Few expected the study would identify the genetic cause of their condition. All elected to receive incidental findings. Interviewees acknowledged paying little attention to potential implications of incidental findings in light of more pressing goals of supporting research regarding their own medical conditions. Interviewees suggested that experience living with a genetic condition prepared them to adjust to incidental findings. Interviewees also expressed little concern about loss of confidentiality of study data. Some experienced the consent process as very long. None desired reconsent prior to return of study results. Families with inherited disease likely would benefit from a consent process in which study risks and benefits were discussed in the context of prior experiences with genetic research and genetic disease. © 2014 Wiley Periodicals, Inc.

  15. Incidental extracerebral findings on brain nonenhanced magnetic resonance imaging: frequency, nondetection rate, and clinical importance

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Ming-Liang; Wei, Xiao-Er [School of Medicine, Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People' s Hospital, Shanghai (China); Lu, Li-Yan [Nanjing Medical University, Department of Radiology, Nanjing First Hospital, Nanjing (China); Li, Wen-Bin [School of Medicine, Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People' s Hospital, Shanghai (China); Kashgar Prefecture Second People' s Hospital, Imaging Center, Kashgar (China)

    2017-03-15

    This study aims to elucidate the frequency, nondetection rate, and clinical importance of incidental extracerebral findings (IECFs) on brain nonenhanced magnetic resonance imaging (MRI). A total of 8284 brain MRIs performed between January 1, 2015 and December 31, 2015 were evaluated for the presence of IECFs and the distribution of IECFs was analyzed. IECFs were categorized as E1 (clinically unimportant, e.g., sinus mucosal thickening); E2 (likely unimportant, e.g., pharyngeal mucosal symmetrical thickening); and E3 (potentially important, e.g., pharyngeal mucosal asymmetrical thickening). The nondetection rate was determined by comparing the results of the structured approach with the initial MRI reports. The medical records were examined for patients with E3 IECFs to assess clinical importance and outcome of these lesions. A total of 5992 IECFs were found in 4469 of the 8284 patients (54.0%). E1 findings constituted 82.2% (4924/5992) of all IECFs; E2 constituted 16.6% (995/5992) and E3 constituted 1.2% (73/5992). Overall IECFs and E1 findings were significantly more common in male patients (P < 0.05). Statistically significant difference was also seen between the different age groups (P < 0.001). The nondetection rate was 56.9% (3409/5992) for overall IECFs and 32.9% (24/73) for E3 IECFs. Of the 73 patients with E3 IECFs, 34 (46.6%) received final diagnosis and appropriate treatment during the study period. IECFs are prevalent in clinical patients on brain MR images with a nondetection rate of 32.9% for potentially important (E3) findings. The reporting of IECFs according to clinical importance is helpful for patients' management. (orig.)

  16. Extraspinal incidental findings on routine MRI of lumbar spine: Prevalence and reporting Rates in 1278 patients

    Energy Technology Data Exchange (ETDEWEB)

    Tuncel, Sedat Alpaslan; Cagli, Bekir; Tekatas, Aslan; Kirici, Yadigar Mehmet; Unlu, Ercument; Genchellac, Haken [Trakya University Faculty of Medicine, Balkan Campus, Edirne (Turkmenistan)

    2015-08-15

    The aim of the present study was to determine the prevalence and reporting rate of incidental findings (IF) in adult outpatients undergoing lumbar magnetic resonance imaging (MRI). Re-evaluation of a total of 1278 lumbar MRI images (collected from patients with a mean age of 50.5 years, range 16-91 years) captured between August 2010-August 2011 was done by a neuroradiologist and a musculoskeletal radiologist. IFs were classified according to organ or system (liver, gallbladder, kidney, bladder, uterus, ovary, lymph node, intestine and aorta). The rate of reporting of a range of IF was examined. The outcome of each patient's treatment was evaluated based on review of hospital records and by telephone interviews. A total of 253 IFs were found in 241 patients (18.8% of 1278). Among these, clinically significant IFs (n = 34) included: 2 renal masses (0.15%), 2 aortic aneurysms (0.15%), 2 cases of hydronephrosis (0.15%), 11 adrenal masses (0.86%), 7 lymphadenopathies (0.55%), 6 cases of endometrial or cervical thickening (0.47%), 1 liver hemangioma (0.08%), 1 pelvic fluid (0.08%) and 2 ovarian dermoid cysts (0.15%). Overall, 28% (71/253) of IFs were included in the clinical reports, while clinically significant findings were reported in 41% (14/34) of cases. Extraspinal IFs are commonly detected during a routine lumbar MRI, and many of these findings are not clinically significant. However, IFs including clinically important findings are occasionally omitted from formal radiological reports.

  17. Disclosing incidental findings in brain research: the rights of minors in decision-making.

    Science.gov (United States)

    Di Pietro, Nina C; Illes, Judy

    2013-11-01

    MRI is used routinely in research with children to generate new knowledge about brain development. The detection of unexpected brain abnormalities (incidental findings; IFs) in these studies presents unique challenges. While key issues surrounding incidence and significance, duty of care, and burden of disclosure have been addressed substantially for adults, less empirical data and normative analyses exist for minors who participate in minimal risk research. To identify ethical concerns and fill existing gaps, we conducted a comprehensive review of papers that focused explicitly on the discovery of IFs in minors. The discourse in the 21 papers retrieved for this analysis amply covered practical issues such as informed consent and screening, difficulties in ascertaining clinical significance, the economic costs and burden of responsibility on researchers, and risks (physical or psychological). However, we found little discussion about the involvement of minors in decisions about disclosure of IFs in the brain, especially for IFs of low clinical significance. In response, we propose a framework for managing IFs that integrates practical considerations with explicit appreciation of rights along the continuum of maturity. This capacity-adjusted framework emphasizes the importance of involving competent minors and respecting their right to make decisions about disclosure. Copyright © 2013 Wiley Periodicals, Inc.

  18. Multiple variations of the coeliac axis, hepatic and renal vasculature as incidental findings illustrated by MDCTA.

    Science.gov (United States)

    Rafailidis, Vasileios; Papadopoulos, Georgios; Kouskouras, Konstantinos; Chryssogonidis, Ioannis; Velnidou, Anastasia; Kalogera-Fountzila, Anna

    2016-08-01

    Vascular anatomical variations are not uncommon and may affect any organ's arterial or venous vasculature. The coexistence of variations in different organic systems is less commonly found, but of great clinical significance in a series of clinical conditions like organ transplantation and surgical preoperative planning. Multidetector computed tomography angiography (MDCTA) has emerged as a valuable alternative to the conventional angiography for accurate evaluation of vascular anatomy and pathology. Radiologists should be familiar with each organ's vascular variations and always report them to the clinician, even if they represent an incidental finding. This case report presents a 52-year-old female patient undergoing abdominal MDCTA for characterization of a renal lesion. This examination revealed the presence of three hilar arteries on the left kidney, a main renal vein in combination with an additional renal vein in both sides along with a replaced right hepatic artery originating from the superior mesenteric artery. Moreover, both inferior phrenic arteries were found originating from the coeliac axis. 3D volume rendering technique images were used in the evaluation of vascular anatomy as illustrated in this case report.

  19. Considering Actionability at the Participant's Research Setting Level for Anticipatable Incidental Findings from Clinical Research.

    Science.gov (United States)

    Ortiz-Osorno, Alberto Betto; Ehler, Linda A; Brooks, Judith

    2015-01-01

    Determining what constitutes an anticipatable incidental finding (IF) from clinical research and defining whether, and when, this IF should be returned to the participant have been topics of discussion in the field of human subject protections for the last 10 years. It has been debated that implementing a comprehensive IF-approach that addresses both the responsibility of researchers to return IFs and the expectation of participants to receive them can be logistically challenging. IFs have been debated at different levels, such as the ethical reasoning for considering their disclosure or the need for planning for them during the development of the research study. Some authors have discussed the methods for re-contacting participants for disclosing IFs, as well as the relevance of considering the clinical importance of the IFs. Similarly, other authors have debated about when IFs should be disclosed to participants. However, no author has addressed how the "actionability" of the IFs should be considered, evaluated, or characterized at the participant's research setting level. This paper defines the concept of "Actionability at the Participant's Research Setting Level" (APRSL) for anticipatable IFs from clinical research, discusses some related ethical concepts to justify the APRSL concept, proposes a strategy to incorporate APRSL into the planning and management of IFs, and suggests a strategy for integrating APRSL at each local research setting. © 2015 American Society of Law, Medicine & Ethics, Inc.

  20. Institutional review board perspectives on obligations to disclose genetic incidental findings to research participants.

    Science.gov (United States)

    Gliwa, Catherine; Yurkiewicz, Ilana R; Lehmann, Lisa Soleymani; Hull, Sara Chandros; Jones, Nathan; Berkman, Benjamin E

    2016-07-01

    Researchers' obligations to disclose genetic incidental findings (GIFs) have been widely debated, but there has been little empirical study of the engagement of institutional review boards (IRBs) with this issue. This article presents data from the first extensive (n = 796) national survey of IRB professionals' understanding of, experience with, and beliefs surrounding GIFs. Most respondents had dealt with questions about GIFs (74%), but only a minority (47%) felt prepared to address them. Although a majority believed that there is an obligation to disclose GIFs (78%), there is still not consensus about the supporting ethical principles. Respondents generally did not endorse the idea that researchers' additional time and effort (7%), and lack of resources (29%), were valid reasons for diminishing a putative obligation. Most (96%) supported a right not to know, but this view became less pronounced (63%) when framed in terms of specific case studies. IRBs are actively engaged with GIFs but have not yet reached consensus. Respondents were uncomfortable with arguments that could be used to limit an obligation to return GIFs. This could indicate that IRBs are providing some of the impetus for the trend toward returning GIFs, although questions remain about the relative contribution of other stakeholders.Genet Med 18 7, 705-711.

  1. Incidental finding of knee osteoarthritis in bone scans performed in obese patients with neoplasia

    International Nuclear Information System (INIS)

    Regalado R, R.; Morales G, R.; Cano P, R.; Mendoza P, G.; Vidal N, L.

    1996-01-01

    Bone scanning performed in the Nuclear Medicine Center (IPEN-INEN) to patients with neoplastic diagnosis between January 1995 and June 1996, permitted the incidental finding of increased uptake images in the knees of 28 patients associated to an asymptomatic arthropathy: osteoarthritis. The histories and bone scanning of this patients were reviewed obtaining their weight, occupation, symptomatology, neoplastic diagnosis and previous scan diagnosis. Patients under 66 years old, asymptomatic, were included, not presenting secondary focuses, without arthropathia antecedent and with a body mass index equal or above class I. The arthropathy was classified according to the localization of the compromised compartment of the knee. >From the body mass index assessment of every patient it was obtained: Class I=12, Class II=11, Class III=3 and Class IV=1. The predominant localization of the osteoarthritic lesions was the patellar zone. We discuss factors that may influence the absence of symptoms of this disease, the relation obesity-osteoarthritis and the usefulness of bone scanning in the diagnosis of this arthropathy in these patients. (authors). 16 refs., 1 fig., 3 tabs

  2. How do clinical genetics consent forms address the familial approach to confidentiality and incidental findings? A mixed-methods study.

    Science.gov (United States)

    Dheensa, Sandi; Crawford, Gillian; Salter, Claire; Parker, Michael; Fenwick, Angela; Lucassen, Anneke

    2018-01-01

    Genetic test results can be relevant to patients and their relatives. Questions thus arise around whether clinicians regard genetic information as confidential to individuals or to families, and about how they broach this and other issues, including the potential for incidental findings, in consent (forms) for genetic testing. We conducted a content analysis of UK-wide genetic testing consent forms and interviewed 128 clinicians/laboratory scientists. We found that almost all genetic services offered patients multiple, sometimes unworkable, choices on forms, including an option to veto the use of familial genetic information to benefit relatives. Participants worried that documented choices were overriding professional judgement and cautioned against any future forms dictating practice around incidental findings. We conclude that 'tick-box' forms, which do little to enhance autonomy, are masking valid consent processes in clinical practice. As genome-wide testing becomes commonplace, we must re-consider consent processes, so that they protects patients'-and relatives'-interests.

  3. Clinical and radiological findings of incidental Rathke's cleft cysts in children and adolescents

    Directory of Open Access Journals (Sweden)

    Yeon Joung Oh

    2014-03-01

    Full Text Available PurposeIn the pediatric population, Rathke's cleft cysts (RCCs are known to be an infrequent cause of headaches, visual disturbances, and pituitary dysfunction. We investigated the clinical characteristics of children in whom RCCs were incidentally discovered and evaluated whether RCCs influence the treatment response of patients with proven endocrinopathy.MethodsA retrospective analysis was conducted in 34 patients with RCCs who were diagnosed between 2006 and 2013 at Hallym University Medical Center. Their clinical, hormonal, and imaging findings were reviewed. We evaluated the clinical outcomes of the patients with concomitant RCCs and endocrinopathy compared to matched controls.ResultsTwenty-six of 34 patients with radiologically proven RCCs had endocrine disorders. They were 9 boys and 17 girls, with ages ranging from 4.8 to 17.4 years at the time of the diagnosis. Of these, 7 (27% had idiopathic short stature, 7 (27% had growth hormone deficiency (GHD, and 12 (46% had central precocious puberty (CPP. Nineteen of 26 patients (73.1% showed low signal intensities on T1-weighted images (T1WI and high signal intensities on T2-weighted images. The incidence of hypointensity on T1WI was higher in the patients with RCCs accompanied by endocrinopathy than in those without endocrinopathy (P=0.033. The treatment outcomes of the patients with CPP and GHD with and without RCCs were similar.ConclusionCPP and GHD patients with a small RCC (less than 20 mm expressing cystic magnetic resonance intensity can be managed with medical treatment, although the RCCs need to be closely monitored in radiological studies to observe their growth.

  4. Local physeal widening on MR imaging: an incidental finding suggesting prior metaphyseal insult

    International Nuclear Information System (INIS)

    Laor, T.; Hartman, A.L.; Jaramillo, D.

    1997-01-01

    To offer a descriptive review which characterizes and evaluates the significance of local physeal widening, (cartilaginous signal extending from the physis into the adjacent metaphysis), identified on magnetic resonance (MR) imaging. MR images (recollected from exams performed between 1988 and 1995) of 31 metaphyses in 22 children where we recognized local physeal widening were examined retrospectively. These areas of physeal widening were evaluated for morphology, depth, location, signal intensity, and the coexistence of epiphyseal alterations. The characteristics of the signal abnormalities were correlated with the duration and type of any identifiable insult to the adjacent metaphysis, and with the development of growth disturbance. Twenty-six metaphyses had identifiable insults (19 single event and 7 sustained or repetitive). The widened physes were of focal tongue (n = 15), broad band (n 10), or mixed (n = 6) morphology. Most (n = 27) areas of widening were isointense with the physeal cartilage on all sequences. Subsequent growth disturbance was more likely when the metaphyseal insult was a single event rather than sustained or repetitive (P = 0.023), with focal tongues (P = 0.029), and with centrally located lesions (P = 0.030). In five cases, the adjacent epiphysis showed signal abnormalities; all developed growth disturbance. Histologic examinations available in two limbs confirmed that the MR findings represented extensions of hypertrophic physeal chondrocytes into the metaphysis. Incidentally observed local physeal widening in a growing bone may represent the imprint of a previous or ongoing interference with endochondral ossification from a prior metaphyseal insult, rather than a primary metaphyseal disorder. Single event insults, physeal widening of focal tongue morphology, central distribution in the metaphysis, and concomitant epiphyseal signal abnormalities on MR imaging are significant predictors of subsequent growth disturbance. (orig.). With 9

  5. Femoral head avascular necrosis: a frequently missed incidental finding on multidetector CT

    International Nuclear Information System (INIS)

    Barille, M.F.; Wu, Jim S.; McMahon, Colm J.

    2014-01-01

    Aim: To determine the incidence of missed femoral head avascular necrosis (AVN) on pelvic computed tomography (CT) performed for clinical indications other than assessment for AVN. Materials and methods: The study was a Health Insurance Portability and Accountability Act (HIPAA)-compliant retrospective study. The picture archiving and communication system (PACS) database was queried for patients with diagnosis of femoral head AVN on magnetic resonance imaging (MRI), who also underwent pelvic multidetector CT after or <30 days before the MRI examination. The MRI and CT images of 144 hips of 72 patients (39 patients with reported AVN on MRI and 33 age-matched controls; mean age = 60 years, 28 male, 44 female), were reviewed in consensus by two readers in a randomized, blinded manner. Using MRI-proven CT-visible AVN as a reference standard, the incidence of missed AVN on initial CT interpretation was determined. Results: Readers confirmed AVN in 33 patients on the MRI images. Nine hips with AVN underwent joint replacement of the affected joint(s) prior to subsequent CT and were excluded. Forty-three MRI-proven AVN cases in 28 patients (15 bilateral, 13 unilateral) were available for analysis. The study readers diagnosed 35/43 (81%) MRI-proven AVN cases in 22/28 (79%) patients. Four of the 35 (11%) cases of MRI-proven, CT-visible AVN were prospectively reported in 3/22 (14%) patients at initial clinical interpretation, with a miss rate of 89% per hip and 86% per patient. Conclusion: Multidetector CT has high accuracy for detection of AVN; however, this is frequently missed as an incidental finding (89% missed in the present study). Assessment for signs of femoral AVN should be part of routine search pattern in interpretation of pelvic CT

  6. Femoral head avascular necrosis: a frequently missed incidental finding on multidetector CT.

    Science.gov (United States)

    Barille, M F; Wu, Jim S; McMahon, Colm J

    2014-03-01

    To determine the incidence of missed femoral head avascular necrosis (AVN) on pelvic computed tomography (CT) performed for clinical indications other than assessment for AVN. The study was a Health Insurance Portability and Accountability Act (HIPAA)-compliant retrospective study. The picture archiving and communication system (PACS) database was queried for patients with diagnosis of femoral head AVN on magnetic resonance imaging (MRI), who also underwent pelvic multidetector CT after or AVN on MRI and 33 age-matched controls; mean age = 60 years, 28 male, 44 female), were reviewed in consensus by two readers in a randomized, blinded manner. Using MRI-proven CT-visible AVN as a reference standard, the incidence of missed AVN on initial CT interpretation was determined. Readers confirmed AVN in 33 patients on the MRI images. Nine hips with AVN underwent joint replacement of the affected joint(s) prior to subsequent CT and were excluded. Forty-three MRI-proven AVN cases in 28 patients (15 bilateral, 13 unilateral) were available for analysis. The study readers diagnosed 35/43 (81%) MRI-proven AVN cases in 22/28 (79%) patients. Four of the 35 (11%) cases of MRI-proven, CT-visible AVN were prospectively reported in 3/22 (14%) patients at initial clinical interpretation, with a miss rate of 89% per hip and 86% per patient. Multidetector CT has high accuracy for detection of AVN; however, this is frequently missed as an incidental finding (89% missed in the present study). Assessment for signs of femoral AVN should be part of routine search pattern in interpretation of pelvic CT. Copyright © 2013 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  7. Incidental Finding of Lamellar Calcification of the Falx Cerebri Leading to the Diagnosis of Gorlin-Goltz Syndrome

    Directory of Open Access Journals (Sweden)

    I. Saulite

    2013-10-01

    Full Text Available Here, we report the case of an incidental finding of lamellar calcification of the falx cerebri in a routine computed tomography scan of the head after an accidental trauma. This lamellar calcification led to the diagnosis of Gorlin-Goltz syndrome (GGS in the patient and her daughter. Lamellar calcification of the falx cerebri is a pathognomonic feature of GGS. Our case report highlights the importance of a multidisciplinary diagnostic approach to GGS.

  8. Incidental finding of lamellar calcification of the falx cerebri leading to the diagnosis of gorlin-goltz syndrome.

    Science.gov (United States)

    Saulite, I; Voykov, B; Mehra, T; Hoetzenecker, W; Guenova, E

    2013-01-01

    Here, we report the case of an incidental finding of lamellar calcification of the falx cerebri in a routine computed tomography scan of the head after an accidental trauma. This lamellar calcification led to the diagnosis of Gorlin-Goltz syndrome (GGS) in the patient and her daughter. Lamellar calcification of the falx cerebri is a pathognomonic feature of GGS. Our case report highlights the importance of a multidisciplinary diagnostic approach to GGS.

  9. Primary thymic extranodal marginal zone B cell lymphoma as an incidental finding in a Caucasian woman

    DEFF Research Database (Denmark)

    Krogh Petersen, Jeanette; Larsen, Thomas Stauffer; Møller, Michael Boe

    2015-01-01

    Primary thymic extranodal marginal zone B cell lymphoma (TML) is an extremely rare lymphoma strongly associated with autoimmune disease. We report an exceedingly rare case of TML found in a non-Asian population. TML was found incidentally in a 60-year-old Caucasian woman with a short history...

  10. Incidental findings of thyroid tissue in cervical lymph nodes: old controversy not yet resolved?

    NARCIS (Netherlands)

    Triantafyllou, A.; Williams, M.D.; Angelos, P.; Shah, J.P.; Westra, W.H.; Hunt, J.L.; Devaney, K.O.; Rinaldo, A.; Slootweg, P.J.; Gnepp, D.R.; Silver, C.; Ferlito, A.

    2016-01-01

    The clinical significance of papillary or follicular thyroid tissue incidentally discovered in cervical lymph nodes during pathological assessment of neck dissections for non-thyroid cancers of the upper aero-digestive tract is critically reviewed. Special emphasis is given to controversies over

  11. Life cycle assessment (LCA)

    DEFF Research Database (Denmark)

    Thrane, Mikkel; Schmidt, Jannick Andresen

    2004-01-01

    The chapter introduces Life Cycle Assessment (LCA) and its application according to the ISO 1404043 standards.......The chapter introduces Life Cycle Assessment (LCA) and its application according to the ISO 1404043 standards....

  12. Incidental extracolonic findings on bright lumen MR colonography in a population at increased risk for colorectal carcinoma

    International Nuclear Information System (INIS)

    Yusuf, Erlangga; Florie, Jasper; Nio, Chung Yung; Jensch, Sebastian; Nievelstein, Rutger A.J.; Baak, Lubbertus; Stoker, Jaap

    2011-01-01

    Purpose: Incidental extracolonic findings affect patient treatment and cost. Therefore, to consider magnetic resonance colonography (MRC) as a tool for colorectal cancer and polyps screening, more knowledge is needed on extracolonic findings. In this study, we sought to determine the prevalence and the spectrum of extracolonic findings in patients with an increased risk colorectal cancer that underwent bright lumen MRC. Materials and methods: MRC examinations were performed in 210 patients. A gadolinium solution was administered rectally for distension of the colon. Extracolonic findings were scored by two radiologists and classified by using C-RADS Reporting System. All findings (with advice regarding work-up) were reported to the patient's physician and followed up for 4.5 years on average. Results: Extracolonic findings were found in 125 (59.5%) patients. Ten (4.8%) had 'potentially important' findings (C-RADS category E4). Twenty-five patients (11.9%) had 'likely unimportant' findings (E3), 90 (42.8%) had 'clinically unimportant' findings (E2) and 85 (40.5%) had a normal exam (E1). In 14 (6.7%) patients additional work-up was performed for their incidentally discovered lesions. In three of them surgery was performed. After work-up, only in two (1.0%) patients a malignancy was found. Conclusion: The number of new relevant extracolonic findings is small and the required additional work-up is limited. This should be considered for implementation of 'bright lumen' MRC as a screening tool.

  13. Incidental head and neck findings on 18F-fluoro-deoxy-glucose positron emission tomography computed tomography.

    Science.gov (United States)

    Williams, S P; Kinshuck, A J; Williams, C; Dwivedi, R; Wieshmann, H; Jones, T M

    2015-09-01

    The overlapping risk factors for lung and head and neck cancer present a definite risk of synchronous malignant pathology. This is the first study to specifically review incidental positron emission tomography computed tomography findings in the head and neck region in lung carcinoma patients. A retrospective review was performed of all lung cancer patients who underwent positron emission tomography computed tomography imaging over a five-year period (January 2008 - December 2012), identified from the Liverpool thoracic multidisciplinary team database. Six hundred and nine patients underwent positron emission tomography computed tomography imaging over this period. In 76 (12.5 per cent) scans, incidental regions of avid 18F-fluoro-deoxy-glucose uptake were reported in the head and neck region. In the 28 patients who were fully investigated, there were 4 incidental findings of malignancy. In lung cancer patients undergoing investigative positron emission tomography computed tomography scanning, a significant number will also present with areas of clinically significant 18F-fluoro-deoxy-glucose uptake in the head and neck region. Of these, at least 5 per cent may have an undiagnosed malignancy.

  14. Incidental finding of multiple well-differentiated papillary mesotheliomas in peritoneum

    DEFF Research Database (Denmark)

    Jakobsen, Mark; Engvad, Birte; Jensen, Thor

    2016-01-01

    We present a case of multiple well-differentiated papillary mesotheliomas (WDPM) in the peritoneum found incidentally in a 63-year-old man with urothelial carcinoma of the bladder. When multiple tumors are seen, malignant mesothelioma should be excluded by histopathological examination as this ma...... with a good prognosis. Great care is needed when diagnosing mesothelial proliferations, given the crucial nature of a benign vs malignant diagnosis. No standardized treatment has yet been established....

  15. LCA and Sustainability

    DEFF Research Database (Denmark)

    Moltesen, Andreas; Bjørn, Anders

    2018-01-01

    LCA is often presented as a sustainability assessment tool. This chapter analyses the relationship between LCA and sustainability. This is done by first outlining the history of the sustainability concept, which gained momentum with the Brundtland Commission’s report ‘Our Common Future report...... is then demonstrated, and the strategy of LCA to achieving environmental protection, namely to guide the reduction of environmental impacts per delivery of a function, is explained. The attempt to broaden the scope of LCA, beyond environmental protection, by so-called life cycle sustainability assessment (LCSA......) is outlined. Finally, the limitations of LCA in guiding a sustainable development are discussed....

  16. Incidental findings on brain Magnetic Resonance Imaging in long-term survivors of breast cancer treated with adjuvant chemotherapy.

    Science.gov (United States)

    Koppelmans, Vincent; Schagen, Sanne B; Poels, Mariëlle M F; Boogerd, Willem; Seynaeve, Caroline; van der Lugt, Aad; Breteler, Monique M B

    2011-11-01

    Incidental brain findings defined as previously undetected abnormalities of potential clinical relevance that are unexpectedly discovered at brain imaging and are unrelated to the purpose of the examination are common in the general population. Because it is unclear whether the prevalence of incidental findings in breast cancer patients treated with chemotherapy is different to that in the general population, we compared the prevalence in breast cancer survivors treated with chemotherapy to that in a population-based sample of women without a history of any cancer. Structural brain MRI (1.5T) was performed in 191 female CMF (Cyclophosphamide, Methotrexate, 5-Fluorouracil) chemotherapy-exposed breast cancer survivors. A reference group of 1590 women without a history of cancer was sampled from a population-based cohort study. All participants were aged 50 to 80 years. Five trained reviewers recorded the brain abnormalities. Two experienced neuro-radiologists reviewed the incidental findings. The cancer survivors had completed chemotherapy on average 21 years before. Of the 191 subjects, 2.6% had an aneurysm and 3.7% had a meningioma. The prevalence of meningiomas and aneurysms was not different between the groups. The prevalence of pituitary macro adenomas in the breast cancer survivors (1.6%) was higher than that in the reference group (0.1%) (OR=23.7; 95% CI 2.3-245.8). Contrary to commonly held opinions, we did not observe an increased prevalence of meningiomas in cancer survivors. Breast cancer survivors previously treated with chemotherapy are more likely to develop pituitary adenomas than persons without a history of cancer and chemotherapy treatment. Copyright © 2011 Elsevier Ltd. All rights reserved.

  17. Pancreatic neuroendocrine tumor - incidental finding during a follow-up CT for primary ovarian carcinoma

    International Nuclear Information System (INIS)

    Ivanova, D.; Balev, B.

    2013-01-01

    Pancreatic neuroendocrine tumors (PNET) are primary, usually we 11-differentiated pancreatic tumors. Their origin is not fully understood, but they are thought to develop from the pluripotent cells in the exocrine part of the pancreas. PNET are a heterogeneous group with different malignant potential. In some of the patients with sporadical forms of PNET there is association with other malignancies such as ovarian cancer, breast cancer, bladder and prostate cancers. We present a case of 50-year-old woman, with incidentally found pancreatic neoplasm, during a follow-up CT for ovarian cancer. Laparotomy and pancreatic biopsy are performed. Histological diagnosis confirms a well- differentiated endocrine tumor of the pancreas. (authors)

  18. Incidental finding of a precaval right renal artery on CT: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hae Seung; Kim, Hyun Cheol; Shin, Hyeong Cheol; Kim, Young Hwa; Nam, Deok Ho; Kim, Il Young; Kim, Hyung Hwan; Bae, Won Kyung [Soonchunhyang University, Cheonan Hospital, Cheonan (Korea, Republic of)

    2005-07-15

    The right renal artery passing anterior to the inferior vena cava is a rare variant of the normal renal arterial anatomy, and identifying this anomaly is important for the planning of minimally invasive renal surgery. The presence of this precaval right renal artery was detected on the contrast-enhanced CT scan by identifying the right renal artery passing anterior to the inferior vena cava. We report here on a case of a precaval right renal artery as a main supplying artery, and this was incidentally found on CT.

  19. Incidental finding of a precaval right renal artery on CT: a case report

    International Nuclear Information System (INIS)

    Lee, Hae Seung; Kim, Hyun Cheol; Shin, Hyeong Cheol; Kim, Young Hwa; Nam, Deok Ho; Kim, Il Young; Kim, Hyung Hwan; Bae, Won Kyung

    2005-01-01

    The right renal artery passing anterior to the inferior vena cava is a rare variant of the normal renal arterial anatomy, and identifying this anomaly is important for the planning of minimally invasive renal surgery. The presence of this precaval right renal artery was detected on the contrast-enhanced CT scan by identifying the right renal artery passing anterior to the inferior vena cava. We report here on a case of a precaval right renal artery as a main supplying artery, and this was incidentally found on CT

  20. Incidental abdominopelvic findings on expanded field-of-view lumbar spinal MRI: frequency, clinical importance, and concordance in interpretation by neuroimaging and body imaging radiologists

    International Nuclear Information System (INIS)

    Maxwell, A.W.P.; Keating, D.P.; Nickerson, J.P.

    2015-01-01

    Aim: To characterize the frequency of identification, clinical importance, and concordance in interpretation of incidental abdominopelvic findings identified on routine lumbar spinal MRI using supplemental expanded field-of-view (FOV) coronal imaging. Materials and methods: All lumbar spinal MRI reports over a 12-month period were retrospectively reviewed for the presence of incidental abdominopelvic findings identified using expanded FOV coronal imaging. Medical records were used to identify those findings that received follow-up, which were then categorized according to final diagnosis and classified as “indeterminate,” “likely clinically unimportant,” and “likely clinically important”. All cases that received follow-up were blindly and independently re-reviewed by a neuroimaging radiologist and body-imaging radiologist, and reviewer performances were compared to assess for agreement with regard to lesion significance, need for follow-up, and other parameters. Results: In total, 2067 reports were reviewed: 687 (33.2%) featured one or more incidental abdominopelvic findings, and 102 (4.9%) findings received further evaluation. Of these, 11 (10.9%) were classified as “indeterminate,” 50 (49%) as “likely clinically unimportant,” and 41 (40.1%) were classified as “likely clinically important.” Excellent agreement was observed between the reviewing radiologists for all evaluated parameters. Conclusion: The addition of an expanded FOV coronal sequence to the standard lumbar spinal MRI protocol was associated with the identification of a large number of incidental abdominopelvic findings, the minority of which represent likely clinically important findings. Most incidental findings were confidently dismissed by a neuroimaging radiologist as likely clinically unimportant without utilization of additional clinical or radiographic resources. - Highlights: • Expanded field-of-view (FOV) MRI improves detection of important incidental findings.

  1. Main Characteristics of LCA

    DEFF Research Database (Denmark)

    Bjørn, Anders; Owsianiak, Mikołaj; Molin, Christine

    2017-01-01

    Life cycle assessment (LCA) has a number of defining characteristics that enables it to address questions that no other assessment tools can address. This chapter begins by demonstrating how the use of LCA in the late 2000s led to a drastic shift in the dominant perception that biofuels were “green......”, “sustainable” or “carbon neutral”, which led to a change in biofuel policies . This is followed by a grouping of the LCA characteristics into four headlines and an explanation of these: (1) takes a life cycle perspective , (2) covers a broad range of environmental issues, (3) is quantitative, (4) is based...... on science. From the insights of the LCA characteristics we then consider the strengths and limitations of LCA and end the chapter by listing 10 questions that LCA can answer and 3 that it cannot....

  2. Gorlin-goltz syndrome, an incidental finding: A rare case report

    Directory of Open Access Journals (Sweden)

    Sanyasi Gandhiraj

    2012-01-01

    Full Text Available Gorlin-Goltz syndrome is an uncommonly found rare disease which shows various possible diverse manifestations of multisystem anomalies, high degree penetration rate with variable expressiveness at least on three body systems. Cutaneous, skeletal, ophthalmological, neurological and reproductive systems are commonly affected in this syndrome. Multiple keratocysts of the jaws are the frequently developed early abnormality than any other. Hereditary autosomal dominant trait is explained as the causative factor for the development of the syndrome. In this case two major and seven minor anomalies were registered. The anomalies found in the patient were not categorized as serious life-threatening abnormalities excepting the multiple keratocysts which were treated by enucleation, curettage and Camoy′s solution application. An incidental detection of Gorlin-Goltz syndrome with multisystem anomalies of a 14-year-old female patient, who had reported for the swelling in the left body of the mandible, is described in this article.

  3. Cystadenocarcinoma of the appendix: an incidental imaging finding in a patient with adenocarcinomas of the ascending and the sigmoid colon

    Directory of Open Access Journals (Sweden)

    Prassopoulos Panos

    2003-10-01

    Full Text Available Abstract Background Primary adenocarcinomas of the appendix are uncommon. Mucoceles that result from mucinous adenocarcinomas of the appendix may be incidentally detected on imaging. Case presentation A case of a mucocele of the appendix, due to cystadenocarcinoma, is presented as an incidental imaging finding in a female, 86-year-old patient. The patient was admitted due to rectal hemorrhage and underwent colonoscopy, x-ray, US and CT. Adenocarcinoma of the ascending colon, adenomatous polyp of the sigmoid colon and a cystic lesion in the right iliac fossa were diagnosed. The cystic lesion was characterized as mucocele. The patient underwent right hemicolectomy, excision of the mucocele and sigmoidectomy. She recovered well and in two-year follow-up is free from cancer. Conclusions Preoperative diagnosis of an underlying malignancy in a mucocele is important for patient management, but it is difficult on imaging studies. Small lymph nodes or soft tissue stranding in the surrounding fat on computed tomography examination may suggest the possibility of malignancy.

  4. Effect of Direct Marketing for Uterine Artery Embolization on Rates of Leiomyomas, Incidental Findings, and Management After Pelvic MRI.

    Science.gov (United States)

    Gurwara, Sheena; Allen, Brian C; Kouri, Brian; Clingan, M Jennings; Picard, Melissa; Leyendecker, John R

    2016-07-01

    The aim of this study was to determine whether a self-referred population screened by an interventional radiology (IR) clinic and a non-IR, physician-referred population differed with regard to suitability for uterine artery embolization (UAE) for symptomatic leiomyomas on the basis of preprocedure MRI. This was an institutional review board-approved, HIPAA-compliant retrospective study of 301 women evaluated in an IR clinic for possible UAE from January 2009 to September 2012. Subjects were retrospectively divided into two groups: self-referred via direct marketing (group A, n = 203; mean age, 41.8 years; range, 22-58 years) and physician referred (group B, n = 98; mean age, 42.9 years; range, 30-65 years). There was no significant difference between groups in presenting symptoms (multiple symptoms, bleeding, bulk-related symptoms, pain). After initial screening, 73.4% of group A (149 of 203) and 79.6% of group B (78 of 98) underwent MRI (P = .242). On the basis of MRI findings, 91.3% of group A (136 of 149) and 94.9% of group B (74 of 78) had uterine leiomyomas (P = .328). Adenomyosis without leiomyoma was present in 4.0% of group A (6 of 149) and 3.8% of group B (3 of 78) (P = .947). Incidental findings requiring further clinical or imaging evaluation were found in 20.8% of group A (31 of 149) and 24.4% of group B (19 of 78) (P = .539). After MRI, 41.6% of group A (62 of 149) and 48.7% of group B (38 of 78) proceeded to UAE (P = .306). After initial screening, similar proportions of self-referred and physician-referred patients were candidates for UAE. The rates of confirmed leiomyomas and incidental findings on MRI were similar between groups. Copyright © 2016 American College of Radiology. All rights reserved.

  5. High rates of clinically relevant incidental findings by total-body CT scanning in trauma patients; results of the REACT-2 trial

    Energy Technology Data Exchange (ETDEWEB)

    Treskes, K.; Bos, S.A.; Sierink, J.C.; Luitse, J.S.K.; Goslings, J.C. [Academic Medical Center, Trauma Unit, Department of Surgery, Amsterdam (Netherlands); Beenen, L.F.M. [Academic Medical Center, Department of Radiology, Amsterdam (Netherlands); Edwards, M.J.R. [Radboud University Medical Center, Department of Trauma and emergency surgery, Nijmegen (Netherlands); Beuker, B.J.A. [University Medical Center Groningen, Trauma Unit, Department of Surgery, Groningen (Netherlands); Muradin, G.S.R. [University Medical Center Rotterdam, Department of Radiology, Erasmus MC, Rotterdam (Netherlands); Hohmann, J. [University of Basel Hospital, Department of Radiology and Nuclear Medicine, Basel (Switzerland); Hollmann, M.W. [Academic Medical Center, Department of Anaesthesiology, Amsterdam (Netherlands); Dijkgraaf, M.G.W. [Academic Medical Center, Clinical Research Unit, Amsterdam (Netherlands); Collaboration: REACT-2 study group

    2017-06-15

    To determine whether there is a difference in frequency and clinical relevance of incidental findings detected by total-body computed tomography scanning (TBCT) compared to those by the standard work-up (STWU) with selective computed tomography (CT) scanning. Trauma patients from five trauma centres were randomized between April 2011 and January 2014 to TBCT imaging or STWU consisting of conventional imaging with selective CT scanning. Incidental findings were divided into three categories: 1) major finding, may cause mortality; 2) moderate finding, may cause morbidity; and 3) minor finding, hardly relevant. Generalized estimating equations were applied to assess differences in incidental findings. In total, 1083 patients were enrolled, of which 541 patients (49.9 %) were randomized for TBCT and 542 patients (50.1 %) for STWU. Major findings were detected in 23 patients (4.3 %) in the TBCT group compared to 9 patients (1.7 %) in the STWU group (adjusted rate ratio 2.851; 95%CI 1.337-6.077; p < 0.007). Findings of moderate relevance were detected in 120 patients (22.2 %) in the TBCT group compared to 86 patients (15.9 %) in the STWU group (adjusted rate ratio 1.421; 95%CI 1.088-1.854; p < 0.010). Compared to selective CT scanning, more patients with clinically relevant incidental findings can be expected by TBCT scanning. (orig.)

  6. Incidental finding of an extensive oropharyngeal mass in magnetic resonance imaging of a patient with temporomandibular disorder: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Omolehinwa, Temitope T.; Mupparapu, Mel; Akintoye, SundayO. [Dept. of Oral Medicine, School of Dental Medicine, University of Pennsylvania, Philadelphia (United States)

    2016-12-15

    In this report, we describe the incidental finding of an oropharyngeal mass in a patient who presented with a chief complaint of temporomandibular pain. The patient was initially evaluated by an otorhinolaryngologist for complaints of headaches, earache, and sinus congestion. Due to worsening headaches and trismus, he was further referred for the management of temporomandibular disorder. The clinical evaluation was uneventful except for limited mouth opening (trismus). An advanced radiological evaluation using magnetic resonance imaging revealed a mass in the nasopharyngeal/oropharyngeal region. The mass occupied the masticatory space and extended superioinferiorly from the skull base to the mandible. A diagnostic biopsy of the lesion revealed a long-standing human papilloma virus (HPV-16)-positive squamous cell carcinoma of the oropharynx. This case illustrates the need for the timely radiological evaluation of seemingly innocuous orofacial pain.

  7. Incidental finding of unilateral isolated aplasia of serratus anterior muscle and winged scapula on chest radiograph: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Joon Sung; Park, Hyun Jin; Ko, Jeong Min [Dept. of Radiology, St. Vincent' s Hospital, College of Medicine, The Catholic University of Korea, Suwon (Korea, Republic of)

    2014-10-15

    The isolated aplasia of the serratus anterior muscle with winging of scapula is very rare, and only a few cases are reported. Here, we present a case of a 30-year-old Korean male who initially presented with a left flank pain. His physical exam did not show any significant finding in his right shoulder. However, his chest radiograph showed absence of right serratus anterior muscle and slightly elevated and medially rotated right scapula. Subsequent CT scan showed the right serratus anterior muscle aplasia and medial winging of the right scapula. This case is unique in two aspects. First, the combination of abnormalities is different from the typical congenital abnormalities involving shoulder girdle, such as Sprengel deformity or Poland syndrome. Secondly, this was incidentally diagnosed with chest radiograph, without clinical impression. Careful reading of chest radiograph can help the radiologists to detect such clinically silent abnormalities.

  8. Minimizing liability risks under the ACMG recommendations for reporting incidental findings in clinical exome and genome sequencing

    Science.gov (United States)

    Evans, Barbara J.

    2014-01-01

    Recent recommendations by the American College of Medical Genetics and Genomics (ACMG) for reporting incidental findings present novel ethical and legal issues. This article expresses no views on the ethical aspects of these recommendations and focuses strictly on liability risks and how to minimize them. The recommendations place labs and clinicians in a new liability environment that exposes them to intentional tort lawsuits as well to traditional suits for negligence. Intentional tort suits are especially troubling because of their potential to inflict ruinous personal financial losses on individual clinicians and laboratory personnel. This article surveys this new liability landscape and describes analytical approaches for minimizing tort liabilities. To a considerable degree, liability risks can be controlled by structuring activities in ways that make future lawsuits nonviable before the suits ever arise. Proactive liability analysis is an effective tool for minimizing tort liabilities in connection with the testing and reporting activities that the ACMG recommends. PMID:24030435

  9. Incidental finding of unilateral isolated aplasia of serratus anterior muscle and winged scapula on chest radiograph: A case report

    International Nuclear Information System (INIS)

    Choi, Joon Sung; Park, Hyun Jin; Ko, Jeong Min

    2014-01-01

    The isolated aplasia of the serratus anterior muscle with winging of scapula is very rare, and only a few cases are reported. Here, we present a case of a 30-year-old Korean male who initially presented with a left flank pain. His physical exam did not show any significant finding in his right shoulder. However, his chest radiograph showed absence of right serratus anterior muscle and slightly elevated and medially rotated right scapula. Subsequent CT scan showed the right serratus anterior muscle aplasia and medial winging of the right scapula. This case is unique in two aspects. First, the combination of abnormalities is different from the typical congenital abnormalities involving shoulder girdle, such as Sprengel deformity or Poland syndrome. Secondly, this was incidentally diagnosed with chest radiograph, without clinical impression. Careful reading of chest radiograph can help the radiologists to detect such clinically silent abnormalities.

  10. Minimizing liability risks under the ACMG recommendations for reporting incidental findings in clinical exome and genome sequencing.

    Science.gov (United States)

    Evans, Barbara J

    2013-12-01

    Recent recommendations by the American College of Medical Genetics and Genomics (ACMG) for reporting incidental findings present novel ethical and legal issues. This article expresses no views on the ethical aspects of these recommendations and focuses strictly on liability risks and how to minimize them. The recommendations place labs and clinicians in a new liability environment that exposes them to intentional tort lawsuits as well to traditional suits for negligence. Intentional tort suits are especially troubling because of their potential to inflict ruinous personal financial losses on individual clinicians and laboratory personnel. This article surveys this new liability landscape and describes analytical approaches for minimizing tort liabilities. To a considerable degree, liability risks can be controlled by structuring activities in ways that make future lawsuits nonviable before the suits ever arise. Proactive liability analysis is an effective tool for minimizing tort liabilities in connection with the testing and reporting activities that the ACMG recommends.

  11. Incidental finding of an extensive oropharyngeal mass in magnetic resonance imaging of a patient with temporomandibular disorder: A case report

    International Nuclear Information System (INIS)

    Omolehinwa, Temitope T.; Mupparapu, Mel; Akintoye, SundayO.

    2016-01-01

    In this report, we describe the incidental finding of an oropharyngeal mass in a patient who presented with a chief complaint of temporomandibular pain. The patient was initially evaluated by an otorhinolaryngologist for complaints of headaches, earache, and sinus congestion. Due to worsening headaches and trismus, he was further referred for the management of temporomandibular disorder. The clinical evaluation was uneventful except for limited mouth opening (trismus). An advanced radiological evaluation using magnetic resonance imaging revealed a mass in the nasopharyngeal/oropharyngeal region. The mass occupied the masticatory space and extended superioinferiorly from the skull base to the mandible. A diagnostic biopsy of the lesion revealed a long-standing human papilloma virus (HPV-16)-positive squamous cell carcinoma of the oropharynx. This case illustrates the need for the timely radiological evaluation of seemingly innocuous orofacial pain

  12. Ecodesign Implementation and LCA

    DEFF Research Database (Denmark)

    McAloone, Tim C.; Pigosso, Daniela Cristina Antelmi

    2018-01-01

    implementation into manufacturing companies. Existing methods and tools for ecodesign implementation will be described, focusing on a multifaceted approach to environmental improvement through product development. Additionally, the use of LCA in an ecodesign implementation context will be further described...... in terms of the challenges and opportunities, together with the discussion of a selection of simplified LCA tools. Finally, a seven-step approach for ecodesign implementation which has been applied by several companies will be described....

  13. LCA of Drinking Water Supply

    DEFF Research Database (Denmark)

    Godskesen, Berit; Meron, Noa; Rygaard, Martin

    2018-01-01

    Water supplies around the globe are growing complex and include more intense treatment methods than just decades ago. Now, desalination of seawater and wastewater reuse for both non-potable and potable water supply have become common practice in many places. LCA has been used to assess...... the potentials and reveal hotspots among the possible technologies and scenarios for water supplies of the future. LCA studies have been used to support decisions in the planning of urban water systems and some important findings include documentation of reduced environmental impact from desalination of brackish...... water over sea water, the significant impacts from changed drinking water quality and reduced environmental burden from wastewater reuse instead of desalination. Some of the main challenges in conducting LCAs of water supply systems are their complexity and diversity, requiring very large data...

  14. Ethical framework for the detection, management and communication of incidental findings in imaging studies, building on an interview study of researchers’ practices and perspectives

    NARCIS (Netherlands)

    E.M. Bunnik (Eline); L. Van Bodegom (Lisa); W. Pinxten (Wim); I.D. de Beaufort (Inez); M.W. Vernooij (Meike)

    2017-01-01

    textabstractBackground: As thousands of healthy research participants are being included in small and large imaging studies, it is essential that dilemmas raised by the detection of incidental findings are adequately handled. Current ethical guidance indicates that pathways for dealing with

  15. Non-traumatic incidental findings in patients undergoing whole-body computed tomography at initial emergency admission.

    Science.gov (United States)

    Kroczek, Eduard K; Wieners, Gero; Steffen, Ingo; Lindner, Tobias; Streitparth, Florian; Hamm, Bernd; Maurer, Martin H

    2017-10-01

    To evaluate the number, localisation and importance of non-traumatic incidental findings (IFs) in patients with suspected or obvious multiple trauma undergoing whole-body CT (WBCT) in a level-1 trauma centre. Between January 2009 and December 2013, a total of 2440 patients with trauma undergoing WBCT at admission to a level-1 trauma centre of a university hospital were retrospectively analysed, through imaging IFs unrelated to trauma with the radiological reports. All IFs were grouped into four categories according to their clinical relevance. Category 1: urgent treatment or further clarification needed; category 2: further examination and follow-up within 3-6 months required; category 3: findings with no immediate consequences for the treatment of the patient but of potential relevance in the future; category 4: harmless findings. Altogether, 5440 IFs in 2440 patients (1735 male, 705 female; mean age 45.1 years) were documented. In 204 patients (8.4%) urgent category 1 findings were reported, 766 patients (31.4%) had category 2 findings, 1236 patients (50.7%) had category 3 findings and 1173 patients (48.1%) had category 4 findings. Most IFs were detected in the abdomen/pelvis (42.5%). 602 (24.7%) of the patients had no IFs. WBCT scans of unrelated trauma patients demonstrate a high rate of IF. A substantial percentage (8.4%) of patients had urgent category 1IFs and a high percentage (31.4%) had category 2 IFs requiring a follow-up. This high number of patients with polytrauma undergoing WBCT, having IFs of high relevance, poses a major challenge for the level-1 trauma centre in the acute and postacute management of these patients. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  16. Incidental findings on cone beam computed tomography scans in cleft lip and palate patients

    NARCIS (Netherlands)

    Kuijpers, M.A.R.; Pazera, A.; Admiraal, R.J.C.; Berge, S.J.; Vissink, A.; Pazera, P.

    2014-01-01

    OBJECTIVES: Cone beam computed tomography (CBCT) is frequently used in treatment planning for alveolar bone grafting (ABG) and orthognathic surgery in patients with cleft lip and palate (CLP). CBCT images may depict coincident findings. The aim of this study was to assess the prevalence of

  17. Mycoplasma hominis: an incidental but significant finding by routine bacteriological culture

    DEFF Research Database (Denmark)

    Gertsen, Jan Berg; Schønheyder, Henrik Carl

    2009-01-01

    bacteriological culture during a 4-year period. Methods: Dpt. of Clinical Microbiology, Aalborg Hospital serves a population of 0.5 mio. Aerobic bacteriologic cultures are routinely carried out on 5% horse blood agar and chocolate agar (SSI Diagnostika, DK) at 35 °C in 5% CO2. The finding of translucent, pinpoint...... not respond to surgical drainage of the abscesses (if present) and prolonged empirical intravenous therapy with a β-lactam antibiotic and metronidazole (median 9 days). The tentative diagnosis of M. hominis prompted a change of antibiotic therapy to either moxifloxacin or clindamycin which was followed...... by resolution of symptoms and normalisation of CRP (median 9 days). Conclusion: M. hominis is a rare finding by prolonged incubation of conventional blood agar. A pathogenic role of M. hominis was supported by the lack of clinical response to surgical drainage and prolonged empirical antibiotic therapy...

  18. Incidental finding of congenital pericardial and mediastinal pleural defect by pneumothorax in an adult

    International Nuclear Information System (INIS)

    Sugiura, Y.; Matsusaka, Y.; Nemoto, E.; Hashizume, T.; Kaseda, S.

    2015-01-01

    Introduction: Congenital pericardial defect (CPD) is an uncommon anomaly. If once cardiac herniation occurs, it threatens life. We report a case of left-sided pneumothorax with consequent protrusion of the heart into left thoracic cavity through not only a large CPD but also congenital pleuropericardium window. Case presentation: A 67-year-old man presenting with sudden-onset left-sided chest pain and slight dyspnea was referred to our hospital. Chest X-ray showed a left lung collapse, and also revealed a pneumopericardium along the right border of the ascending aorta. Subsequent computed tomography (CT) scan revealed that the heart was displaced into the left hemithorax. Thus, we diagnosed the patient with pneumothorax and a defect of the pericardial and mediastinal pleurae. Subsequently, a chest tube was inserted into the left thoracic cavity, and the collapsed lung was promptly inflated. The cardiac position was reinstated within mediastinum as evidenced by follow-up CT scan. The QRS axis on his electrocardiogram (ECG) was altered from 52° to 73°. Together with the cardiac relocation evidenced by the QRS axis shift on ECG and findings of CT, we determined that there was a low potential for complications and opted against surgical repair. Discussion: When the CPD is sufficiently large, surgical intervention is not necessary. The size of the CPD can be assessed not only by CT findings, but the alteration of the QRS axis on ECG also provides useful information whether cardiac herniation can be resolved by the inflated lung. - Highlights: • We reported a case of congenital pericardial defect (CPD) with pneumothorax. • We described how to manage to alleviate life-threatening complications. • The size of CPD was assessed by CT findings and the alteration of QRS axis on ECG

  19. Research cardiac magnetic resonance imaging in end stage renal disease - incidence, significance and implications of unexpected incidental findings

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Elaine; Weir-McCall, Jonathan R.; Houston, J.G.; Struthers, Allan D. [Ninewells Hospital, Division of Cardiovascular and Diabetes Medicine, Dundee (United Kingdom); Patel, Rajan K.; Jardine, Alan G.; Mark, Patrick B. [Institute of Cardiovascular and Medical Sciences, Glasgow (United Kingdom); Roditi, Giles [NHS Greater Glasgow and Clyde, Department of Radiology, Glasgow Royal Infirmary, Glasgow (United Kingdom)

    2017-01-15

    Left ventricular mass (LVM) at cardiac magnetic resonance imaging (CMR) is a frequent end point in clinical trials in nephrology. Trial participants with end stage renal disease (ESRD) may have a greater frequency of incidental findings (IF). We retrospectively investigated prevalence of IF in previous research CMR and reviewed their subsequent impact on participants. Between 2002 and 2006, 161 ESRD patients underwent CMR in a transplant assessment study. Images were used to assess LV mass and function. In the current study a radiologist reviewed the scans for IF. Review of patient records determined the subsequent clinical significance of IF. There were 150 IF in 95 study participants. Eighty-four (56 %) were new diagnoses. One hundred and two were non-cardiac. Fifteen were suspicious of malignancy. There was a clinically significant IF for 14.9 % of the participants. In six cases earlier identification of an IF may have improved quality of life or survival. Without radiology support clinically important IF may be missed on CMR. Patients undergoing CMR in trials should be counselled about the frequency and implications of IF. Patients with ESRD have a higher prevalence of IF than reported in other populations. Nephrology studies require mechanisms for radiologist reporting and strategies for dealing with IF. (orig.)

  20. Gorlin-Goltz syndrome: incidental finding on routine ct scan following car accident.

    Science.gov (United States)

    Kalogeropoulou, Christina; Zampakis, Petros; Kazantzi, Santra; Kraniotis, Pantelis; Mastronikolis, Nicholas S

    2009-11-25

    Gorlin-Goltz syndrome is a rare hereditary disease. Pathogenesis of the syndrome is attributed to abnormalities in the long arm of chromosome 9 (q22.3-q31) and loss or mutations of human patched gene (PTCH1 gene). Multiple basal cell carcinomas (BCCs), odontogenic keratocysts, skeletal abnormalities, hyperkeratosis of palms and soles, intracranial ectopic calcifications of the falx cerebri and facial dysmorphism are considered the main clinical features. Diagnosis is based upon established major and minor clinical and radiological criteria and ideally confirmed by DNA analysis. Because of the different systems affected, a multidisciplinary approach team of various experts is required for a successful management. We report the case of a 19 year-old female who was involved in a car accident and found to present imaging findings of Gorlin-Goltz syndrome during a routine whole body computed tomography (CT) scan in order to exclude traumatic injuries. Radiologic findings of the syndrome are easily identifiable on CT scans and may prompt to early verification of the disease, which is very important for regular follow-up and better survival rates from the co-existent diseases.

  1. Incidental finding of both cholecystoduodenal fistula and caecum carcinoma with MDCT imaging

    International Nuclear Information System (INIS)

    Groudeva, V.; Adam, G.; Malla Houech, I-V.; Davidkov, L.; Stoinova, V.

    2015-01-01

    Full text: Bouveret’s syndrome is a rare condition of gastric outlet obstruction, due to the impaction of gallstones in the duodenum. Most commonly it affects women and usually a history of cholelithiasis is present. We present the case of 86 years old female, with complaints of fullness, belching, acids, loss of appetite and weight for a few weeks. The examination revealed soft abdomen, painful palpation and a palpable movable mass in the right lower quadrant. The patient was referred to the imaging department for assessment of the finding. MDCT of the abdomen was carried out on 320 - row Aquillion ONE Toshiba machine, using contrast medium. The aim is to clarifying the accurate managing of the diagnosis of cholecystoduodenal fistula using MDCT. MDCT identified the presence of two independent from one another diseases, characterized by similar complaints. An enhancing mass with irregular borders in the caecal area was visualized. In addition presence of pneumobilia and a communication extending from the gallbladder to the duodenum and calculi in the latter were identified.The findings were consistent with cholecystoduodenal fistula. the patient underwent surgery, right hemicolectomy was performed together with duodenotomy and calculus extraction. Different conditions may present with overlapping symptoms and imaging diagnostic comes in help with the investigation. Since the condition of cholecystoduodenal fistula is associated with high risk of complications and death, it appeals to quick diagnosis and treatment. the use of MDCT in clinical practice as a non-invasive method allows precise identification of the signs of this disease

  2. Brain MRI findings in patients with initial cerebral thrombosis and the relationship between incidental findings, aging and dementia

    International Nuclear Information System (INIS)

    Iwamoto, Toshihiko; Okada, Toyohiro; Ogawa, Kimikazu; Yanagawa, Kiyotaka; Uno, Masanobu; Takasaki, Masaru

    1994-01-01

    To estimate the relationship between aging, dementia and changes observed on magnetic resonance imaging (MRI) seen in elderly patients with cerebral thrombosis, MRI findings in 103 patients with an initial stroke event (thrombosis group) were compared with those of 37 patients with hypertension/diabetes (high risk group) and 78 patients without those disorders (low risk group). In addition to the causative lesions in the thrombosis group, periventricular hyperintensities (PVH), spotty lesions (SL), silent infarctions (SI), ventricular dilatation (VD), and cortical atrophy (CA) were analyzed in these groups. Infarctions located in the internal capsule/corona radiata were the most frequent causative lesion. Compared to the low risk group, a high incidence of patchy/diffuse PVH, SI, and severe CA was seen in both the thrombosis group and the high risk group. Widespread PVH and multiple SL increased with age in the thrombosis group, while severe CA was seen in each group. SI and VD tended to increase after age 60, though they were not significant. Dementia, diagnosed in 40 out of 78 patients, increased with age. Multivariate analysis revealed the degree of the effects of MRI findings on dementia to be marked in PVH, brain atrophy, causative lesions, and SL, in that order. These results indicated that diffuse PVH and brain atrophy, developing with age, promoted dementia in the elderly with vascular lesions. Moreover, they suggested that a variety of silent brain lesions recognized on MRI other than infarction can affect symptoms in the elderly. (author)

  3. LCA of Energy Systems

    DEFF Research Database (Denmark)

    Laurent, Alexis; Espinosa Martinez, Nieves; Hauschild, Michael Zwicky

    2018-01-01

    Energy systems are essential in the support of modern societies’ activities, and can span a wide spectrum of electricity and heat generation systems and cooling systems. Along with their central role and large diversity, these systems have been demonstrated to cause serious impacts on human health...... , ecosystems and natural resources. Over the past two decades, energy systems have thus been the focus of more than 1000 LCA studies, with the aim to identify and reduce these impacts. This chapter addresses LCA applications to energy systems for generation of electricity and heat . The chapter gives insight...

  4. Primary hydatid disease of the femur: unsuspected and incidental MRI findings with long-term curative results on medical treatment alone

    International Nuclear Information System (INIS)

    Poyanli, A.; Sencer, S.; Akan, K.; Poyanli, O.; Sayrak, H.

    2001-01-01

    This report describes the early magnetic resonance imaging (MRI) findings and long-term follow-up results of albendazole treatment in a 16-year-old girl with primary hydatid disease of the femur diagnosed incidentally during the course of a post-traumatic knee infection. As far as we know, this is the first report of the early MRI findings and long-term outcome of medical treatment in primary hydatid disease of the femur in this age group. (orig.)

  5. Primary hydatid disease of the femur: unsuspected and incidental MRI findings with long-term curative results on medical treatment alone

    Energy Technology Data Exchange (ETDEWEB)

    Poyanli, A.; Sencer, S. [Dept. of Radiology, Istanbul Faculty of Medicine (Turkey); Akan, K.; Poyanli, O. [Dept. of Orthopaedics and Traumatology, Goeztepe SSK Educational Hospital, Istanbul (Turkey); Sayrak, H. [Dept. of Pathology, Goeztepe SSK Educational Hospital, Istanbul (Turkey)

    2001-11-01

    This report describes the early magnetic resonance imaging (MRI) findings and long-term follow-up results of albendazole treatment in a 16-year-old girl with primary hydatid disease of the femur diagnosed incidentally during the course of a post-traumatic knee infection. As far as we know, this is the first report of the early MRI findings and long-term outcome of medical treatment in primary hydatid disease of the femur in this age group. (orig.)

  6. Intracranial haemorrhage: an incidental finding at magnetic resonance imaging in a cohort of late preterm and term infants

    Energy Technology Data Exchange (ETDEWEB)

    Sirgiovanni, Ida; Groppo, Michela; Bassi, Laura; Passera, Sofia; Schiavolin, Paola; Fumagalli, Monica; Mosca, Fabio [Universita degli Studi di Milano, Neonatal Intensive Care Unit, Department of Clinical Science and Community Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan (Italy); Avignone, Sabrina; Cinnante, Claudia; Triulzi, Fabio [Universita degli Studi di Milano, Department of Neuroradiology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan (Italy); Lista, Gianluca [V. Buzzi Children' s Hospital, ICP, Neonatal Intensive Care Unit, Milan (Italy)

    2014-03-15

    Intracranial haemorrhage (ICH) in term newborns has been increasingly recognised but the occurrence in late preterm infants and the clinical presentation are still unclear. To investigate the appearance of intracranial haemorrhage at MRI in a cohort of infants born at 34 weeks' gestation or more and to correlate MRI findings with neonatal symptoms. We retrospectively reviewed neonatal brain MRI scans performed during a 3-year period. We included neonates ≥34 weeks' gestation with intracranial haemorrhage and compared findings with those in babies without intracranial haemorrhage. Babies were classified into three groups according to haemorrhage location: (1) infratentorial, (2) infra- and supratentorial, (3) infra- and supratentorial + parenchymal involvement. Intracranial haemorrhage was observed in 36/240 babies (15%). All of these 36 had subdural haemorrhage. Sixteen babies were included in group 1; 16 in group 2; 4 in group 3. All infants in groups 1 and 2 were asymptomatic except one who was affected by intraventricular haemorrhage grade 3. Among the infants in group 3, who had intracranial haemorrhage with parenchymal involvement, three of the four (75%) presented with acute neurological symptoms. Uncomplicated spontaneous vaginal delivery was reported in 20/36 neonates (56%), vacuum extraction in 4 (11%) and caesarean section in 12 (33%). Babies with intracranial haemorrhage had significantly higher gestational age (38 ± 2 weeks vs. 37 ± 2 weeks) and birth weight (3,097 ± 485 g vs. 2,803 ± 741 g) compared to babies without intracranial haemorrhage and were more likely to be delivered vaginally than by caesarian section. Mild intracranial haemorrhage (groups 1 and 2) is relatively common in late preterm and term infants, although it mostly represents an incidental finding in clinically asymptomatic babies; early neurological symptoms appear to be related to parenchymal involvement. (orig.)

  7. Incidental Anatomic Finding of Celiacomesenteric Trunk Associated with 'Nutcracker Phenomenon,' or Compression of the Left Renal Vein.

    Science.gov (United States)

    Peterson, Joshua; Hage, Anthony N; Diljak, Stephan; Long, Benjamin D; Marcusa, Daniel P; Stribley, John M; Brzezinski, David W; Eliason, Jonathan

    2017-12-15

    BACKGROUND Celiacomesenteric trunk (CMT) is a very rare anatomic finding in which the celiac artery and the superior mesenteric artery (SMA) originate from the abdominal aorta through a common trunk. Clinical associations with CMT include arterial aneurysm, thrombosis, and celiac artery compression. However, an association between CMT and abdominal venous congestion caused by left renal vein compression, or 'nutcracker phenomenon,' has not been previously reported. CASE REPORT A 91-year-old woman, who died from a cerebrovascular accident (CVA), underwent a cadaveric examination at our medical school. On examination of the abdomen, there was an incidental finding of CMT. The arterial and venous diameters were measured, and vascular histopathology was undertaken. The vascular anatomy was consistent with CMT type 1-b. Nutcracker phenomenon (NCP) (left renal vein compression) was seen anatomically as dilatation and engorgement of the left renal vein, relative to the right renal vein (10.77±0.13 mm vs. 4.49±0.56 mm, respectively), and dilatation and engorgement of the left ovarian vein, relative to the right ovarian vein (4.37±0.15 mm vs. 1.06±0.09 mm, respectively) with left ovarian varicocele. The aortoceliac angle (ACA) and the aortomesenteric angle (AMA) approached zero degrees. CONCLUSIONS We have described a rare anatomic finding of CMT that created an acute AMA and NCP. Awareness of this rare association between CMT and NCP by clinicians, vascular surgeons, and radiologists may be of value in the future evaluation and surgical management of patients who present clinically with 'nutcracker syndrome.'

  8. Intracranial haemorrhage: an incidental finding at magnetic resonance imaging in a cohort of late preterm and term infants

    International Nuclear Information System (INIS)

    Sirgiovanni, Ida; Groppo, Michela; Bassi, Laura; Passera, Sofia; Schiavolin, Paola; Fumagalli, Monica; Mosca, Fabio; Avignone, Sabrina; Cinnante, Claudia; Triulzi, Fabio; Lista, Gianluca

    2014-01-01

    Intracranial haemorrhage (ICH) in term newborns has been increasingly recognised but the occurrence in late preterm infants and the clinical presentation are still unclear. To investigate the appearance of intracranial haemorrhage at MRI in a cohort of infants born at 34 weeks' gestation or more and to correlate MRI findings with neonatal symptoms. We retrospectively reviewed neonatal brain MRI scans performed during a 3-year period. We included neonates ≥34 weeks' gestation with intracranial haemorrhage and compared findings with those in babies without intracranial haemorrhage. Babies were classified into three groups according to haemorrhage location: (1) infratentorial, (2) infra- and supratentorial, (3) infra- and supratentorial + parenchymal involvement. Intracranial haemorrhage was observed in 36/240 babies (15%). All of these 36 had subdural haemorrhage. Sixteen babies were included in group 1; 16 in group 2; 4 in group 3. All infants in groups 1 and 2 were asymptomatic except one who was affected by intraventricular haemorrhage grade 3. Among the infants in group 3, who had intracranial haemorrhage with parenchymal involvement, three of the four (75%) presented with acute neurological symptoms. Uncomplicated spontaneous vaginal delivery was reported in 20/36 neonates (56%), vacuum extraction in 4 (11%) and caesarean section in 12 (33%). Babies with intracranial haemorrhage had significantly higher gestational age (38 ± 2 weeks vs. 37 ± 2 weeks) and birth weight (3,097 ± 485 g vs. 2,803 ± 741 g) compared to babies without intracranial haemorrhage and were more likely to be delivered vaginally than by caesarian section. Mild intracranial haemorrhage (groups 1 and 2) is relatively common in late preterm and term infants, although it mostly represents an incidental finding in clinically asymptomatic babies; early neurological symptoms appear to be related to parenchymal involvement. (orig.)

  9. Reducing false-positive incidental findings with ensemble genotyping and logistic regression based variant filtering methods.

    Science.gov (United States)

    Hwang, Kyu-Baek; Lee, In-Hee; Park, Jin-Ho; Hambuch, Tina; Choe, Yongjoon; Kim, MinHyeok; Lee, Kyungjoon; Song, Taemin; Neu, Matthew B; Gupta, Neha; Kohane, Isaac S; Green, Robert C; Kong, Sek Won

    2014-08-01

    As whole genome sequencing (WGS) uncovers variants associated with rare and common diseases, an immediate challenge is to minimize false-positive findings due to sequencing and variant calling errors. False positives can be reduced by combining results from orthogonal sequencing methods, but costly. Here, we present variant filtering approaches using logistic regression (LR) and ensemble genotyping to minimize false positives without sacrificing sensitivity. We evaluated the methods using paired WGS datasets of an extended family prepared using two sequencing platforms and a validated set of variants in NA12878. Using LR or ensemble genotyping based filtering, false-negative rates were significantly reduced by 1.1- to 17.8-fold at the same levels of false discovery rates (5.4% for heterozygous and 4.5% for homozygous single nucleotide variants (SNVs); 30.0% for heterozygous and 18.7% for homozygous insertions; 25.2% for heterozygous and 16.6% for homozygous deletions) compared to the filtering based on genotype quality scores. Moreover, ensemble genotyping excluded > 98% (105,080 of 107,167) of false positives while retaining > 95% (897 of 937) of true positives in de novo mutation (DNM) discovery in NA12878, and performed better than a consensus method using two sequencing platforms. Our proposed methods were effective in prioritizing phenotype-associated variants, and an ensemble genotyping would be essential to minimize false-positive DNM candidates. © 2014 WILEY PERIODICALS, INC.

  10. Nine cases of nonpalpable testicular mass. An incidental finding in a large scale ultrasonography survey

    International Nuclear Information System (INIS)

    Avci, A.; Eken, C.; Ozgok, Y.; Erol, B.

    2008-01-01

    Nonpalpable testicular masses are usually diagnosed during routine ultrasonography (US) examinations for other conditions. There are conflicting results on the final diagnosis and management of these lesions. In the present study we report the results of a large US series of 5104 patients on nonpalpable testicular masses and discuss the management of these patients. This retrospective observational study was performed in a secondary care military hospital. A total of 5104 patients underwent a US and 11 of them were diagnosed as having a nonpalpable testicular mass. These 11 patients also underwent magnetic resonance imaging (MRI). Two of them refused surgery and were excluded from the study. The remaining nine patients underwent intraoperative US-guided localization and excisional biopsy of the non-palpable testicular parenchymal mass. A radical orchiectomy was required in all of them. US and MRI findings, frozen and final pathology results were recorded. The median age of study subjects was 24 years. The final pathology revealed a malign tumor in eight patients and an inflammatory mass in one patient. There were inconsistent results in four patients between frozen section analysis and final pathology. MRI improved the definition of the solid masses in all patients. MRI enhances the certainty of the diagnosis of malignity in nonpalpable testicular masses, particularly in conditions that generally can not be diagnosed with ultrasonography alone. Frozen section analysis is not an accredited method in diagnosing malign lesions in non-palpable testicular masses. (author)

  11. Introduction to LCA Methodology

    DEFF Research Database (Denmark)

    Hauschild, Michael Z.

    2018-01-01

    In order to offer the reader an overview of the LCA methodology in the preparation of the more detailed description of its different phases, a brief introduction is given to the methodological framework according to the ISO 14040 standard and the main elements of each of its phases. Emphasis...

  12. LCA Experiences in Danish Industry

    DEFF Research Database (Denmark)

    Broberg, Ole; Christensen, Per

    1999-01-01

    of the products with subsequent new priorities in the environmental efforts. Only a few enterprises have built up in-house LCA competence whereas consultants are heavily involved in LCA work. In large enterprises LCA work is pre-dominantly carried out by environmental staff members, but also product development...

  13. Abdominal Hernias, Giant Colon Diverticulum, GIST, Intestinal Pneumatosis, Colon Ischemia, Cold Intussusception, Gallstone Ileus, and Foreign Bodies: Our Experience and Literature Review of Incidental Gastrointestinal MDCT Findings

    Science.gov (United States)

    Gatta, G.; Rella, R.; Donatello, D.; Falco, G.; Grassi, R.

    2017-01-01

    Incidental gastrointestinal findings are commonly detected on MDCT exams performed for various medical indications. This review describes the radiological MDCT spectrum of appearances already present in the past literature and in today's experience of several gastrointestinal acute conditions such as abdominal hernia, giant colon diverticulum, GIST, intestinal pneumatosis, colon ischemia, cold intussusception, gallstone ileus, and foreign bodies which can require medical and surgical intervention or clinical follow-up. The clinical presentation of this illness is frequently nonspecific: abdominal pain, distension, nausea, fever, rectal bleeding, vomiting, constipation, or a palpable mass, depending on the disease. A proper differential diagnosis is essential in the assessment of treatment and in this case MDCT exam plays a central rule. We wish that this article will familiarize the radiologist in the diagnosis of this kind of incidental MDCT findings for better orientation of the therapy. PMID:28638830

  14. Abdominal Hernias, Giant Colon Diverticulum, GIST, Intestinal Pneumatosis, Colon Ischemia, Cold Intussusception, Gallstone Ileus, and Foreign Bodies: Our Experience and Literature Review of Incidental Gastrointestinal MDCT Findings

    Directory of Open Access Journals (Sweden)

    G. Di Grezia

    2017-01-01

    Full Text Available Incidental gastrointestinal findings are commonly detected on MDCT exams performed for various medical indications. This review describes the radiological MDCT spectrum of appearances already present in the past literature and in today’s experience of several gastrointestinal acute conditions such as abdominal hernia, giant colon diverticulum, GIST, intestinal pneumatosis, colon ischemia, cold intussusception, gallstone ileus, and foreign bodies which can require medical and surgical intervention or clinical follow-up. The clinical presentation of this illness is frequently nonspecific: abdominal pain, distension, nausea, fever, rectal bleeding, vomiting, constipation, or a palpable mass, depending on the disease. A proper differential diagnosis is essential in the assessment of treatment and in this case MDCT exam plays a central rule. We wish that this article will familiarize the radiologist in the diagnosis of this kind of incidental MDCT findings for better orientation of the therapy.

  15. Abdominal Hernias, Giant Colon Diverticulum, GIST, Intestinal Pneumatosis, Colon Ischemia, Cold Intussusception, Gallstone Ileus, and Foreign Bodies: Our Experience and Literature Review of Incidental Gastrointestinal MDCT Findings.

    Science.gov (United States)

    Di Grezia, G; Gatta, G; Rella, R; Donatello, D; Falco, G; Grassi, R; Grassi, R

    2017-01-01

    Incidental gastrointestinal findings are commonly detected on MDCT exams performed for various medical indications. This review describes the radiological MDCT spectrum of appearances already present in the past literature and in today's experience of several gastrointestinal acute conditions such as abdominal hernia, giant colon diverticulum, GIST, intestinal pneumatosis, colon ischemia, cold intussusception, gallstone ileus, and foreign bodies which can require medical and surgical intervention or clinical follow-up. The clinical presentation of this illness is frequently nonspecific: abdominal pain, distension, nausea, fever, rectal bleeding, vomiting, constipation, or a palpable mass, depending on the disease. A proper differential diagnosis is essential in the assessment of treatment and in this case MDCT exam plays a central rule. We wish that this article will familiarize the radiologist in the diagnosis of this kind of incidental MDCT findings for better orientation of the therapy.

  16. Abdominal Hernias, Giant Colon Diverticulum, GIST, Intestinal Pneumatosis, Colon Ischemia, Cold Intussusception, Gallstone Ileus, and Foreign Bodies: Our Experience and Literature Review of Incidental Gastrointestinal MDCT Findings

    OpenAIRE

    Di Grezia, G.; Gatta, G.; Rella, R.; Donatello, D.; Falco, G.; Grassi, R.; Grassi, R.

    2017-01-01

    Incidental gastrointestinal findings are commonly detected on MDCT exams performed for various medical indications. This review describes the radiological MDCT spectrum of appearances already present in the past literature and in today’s experience of several gastrointestinal acute conditions such as abdominal hernia, giant colon diverticulum, GIST, intestinal pneumatosis, colon ischemia, cold intussusception, gallstone ileus, and foreign bodies which can require medical and surgical interven...

  17. Future-Oriented LCA

    DEFF Research Database (Denmark)

    Olsen, Stig Irving; Borup, Mads; Andersen, Per Dannemand

    2018-01-01

    LCA is often applied for decision-making that concerns actions reaching near or far into the future. However, traditional life cycle assessment methodology must be adjusted for the prospective and change-oriented purposes, but no standardised way of doing this has emerged yet. In this chapter some...... challenges are described and some learnings are derived. Many of the future-oriented LCAs published so far perform relatively short-term prediction of simple comparisons. But for more long-term time horizons foresight methods can be of help. Scenarios established by qualified experts about future...... technological and economic developments are indispensable in future technology assessments. The uncertainties in future-oriented LCAs are to a large extent qualitative and it is important to emphasise that LCA of future technologies will provide a set of answers and not ‘the’ answer....

  18. Coronary dual source multi detector computed tomography in patients suspected of coronary artery disease: Prevalence of incidental extra-cardiac findings

    International Nuclear Information System (INIS)

    Bendix, K.; Jensen, J.M.; Poulsen, S.; Mygind, N.; Norgaard, B.L.

    2011-01-01

    Objectives: (1) To establish the prevalence of incidental extra-cardiac findings (ECFs) in coronary multi detector computed tomography (CCT) performed in a large, homogeneous cohort of patients suspected of coronary artery disease (CAD). (2) To examine whether any association can be established between ECFs and pretest risk as determined by conventional risk factors for CAD, the Diamond-Forrester risk model or coronary artery calcium scores. (3) To assess cost related to extra-cardiac examinations. Design: Retrospective study of consecutive patients who had CCT performed. A large field of view was recreated from the non-enhanced CT scan and evaluated by a radiologist for incidental ECFs. Subjects: Patients with chest pain referred to CTA by a cardiologist. Results: In 1383 patients a total of 481 ECFs were indentified, 378 minor (meaning no follow-up was needed) and 103 major ECFs (ECF followed up clinically and/or with additional imaging), in a total of 393 (28%) patients. 85 (6%) patients had one major ECF and 9 (0.7%) patients had two major ECFs. In 19 (4 cases of malignancy) patients the major ECF had therapeutic consequences. Significant positive associations were found between age and smoking, respectively and the presence of ECFs. The cost estimate of saving one life from malignant disease based on ECF examinations is 40,190 Euro . Conclusion: Incidental extra-cardiac findings are common, sometimes revealing serious, even malignant disease. Diagnostic follow-up of major ECFs seems to be cost-effective in a Danish clinical setting. We recommend investigating a large field of view for incidental ECFs following CCT.

  19. LCA of Wastewater Treatment

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred

    2018-01-01

    of LCA studies addressing wastewater treatment have from the very first published cases, been on energy and resource consumption. In recent time, the use of characterisation has increased and besides global warming potential, especially eutrophication is in focus. Even the toxicity-related impact......The main purpose of wastewater treatment is to protect humans against waterborne diseases and to safeguard aquatic bio-resources like fish. The dominating environmental concerns within this domain are indeed still potential aquatic eutrophication/oxygen depletion due to nutrient/organic matter...

  20. Incidental Findings in Abdominal Dual-Energy Computed Tomography: Correlation Between True Noncontrast and Virtual Noncontrast Images Considering Renal and Liver Cysts and Adrenal Masses.

    Science.gov (United States)

    Slebocki, Karin; Kraus, Bastian; Chang, De-Hua; Hellmich, Martin; Maintz, David; Bangard, Christopher

    To assess correlation between attenuation measurements of incidental findings in abdominal second generation dual-energy computed tomography (CT) on true noncontrast (TNC) and virtual noncontrast (VNC) images. Sixty-three patients underwent arterial dual-energy CT (Somatom Definition Flash, Siemens; pitch factor, 0.75-1.0; gantry rotation time, 0.28 seconds) after endovascular aneurysm repair, consisting of a TNC single energy CT scan (collimation, 128 × 0.6 mm; 120 kVp) and a dual-energy arterial phase scan (collimation, 32 × 0.6 mm, 140 and 100 kVp; blended, 120 kVp data set). Attenuation measurements in Hounsfield units (HU) of liver parenchyma and incidental findings like renal and hepatic cysts and adrenal masses on TNC and VNC images were done by drawing regions of interest. Statistical analysis was performed by paired t test and Pearson correlation. Incidental findings were detected in 56 (89%) patients. There was excellent correlation for both renal (n = 40) and hepatic cysts (n = 12) as well as adrenal masses (n = 6) with a Pearson correlation of 0.896, 0.800, and 0.945, respectively, and mean attenuation values on TNC and VNC images of 10.6 HU ± 12.8 versus 5.1 HU ± 17.5 (attenuation value range from -8.8 to 59.1 HU vs -11.8 to 73.4 HU), 6.4 HU ± 5.8 versus 6.3 HU ± 4.6 (attenuation value range from 2.0 to 16.2 HU vs -3.0 to 15.9 HU), and 12.8 HU ± 11.2 versus 12.4 HU ± 10.2 (attenuation value range from -2.3 to 27.5 HU vs -2.2 to 23.6 HU), respectively. As proof of principle, liver parenchyma measurements also showed excellent correlation between TNC and VNC (n = 40) images with a Pearson correlation of 0.839 and mean attenuation values on TNC and VNC images of 47.2 HU ± 10.5 versus 43.8 HU ± 8.7 (attenuation value range from 21.9 to 60.2 HU vs 4.5 to 65.3 HU). In conclusion, attenuation measurements of incidental findings like renal cysts or adrenal masses on TNC and VNC images derived from second generation dual-energy CT scans show excellent

  1. Incidental findings in paranasal sinuses and mastoid cells. A cross-sectional magnetic resonance imaging (MRI) study in a pediatric radiology department

    International Nuclear Information System (INIS)

    Kalle, T. von; Fabig-Moritz, C.; Winkler, P.; Heumann, H.

    2012-01-01

    Purpose: Misdiagnosis of 'sinusitis' is still frequent in children, although mucosal swelling in the paranasal sinuses of children has been reported as a common incidental finding. Recent radiological publications on the problem are rare. We prospectively evaluated the mucosal thickening in the paranasal sinuses and mastoid cells of children who underwent MRI of the head for reasons other than sinusitis or mastoiditis. Materials and Methods: 147 patients, 0.2 - 22.7 years, median 8.9. Axial and sagittal T2 TSE images were evaluated by two experienced pediatric radiologists. Categories for the degree of mucosal swelling were for the maxillary, frontal and sphenoid sinuses: no swelling, minor: 50 %. Results: 61 % of children had one or more salient findings in their paranasal sinuses or mastoid cells. 48 % had mucosal swelling in their paranasal cavities, 25 % in their mastoid cells. The prevalence was higher among children less than 10 years of age (60 % and 42 %) and among children with current upper respiratory tract infection (71 % and 35 %). There was no correlation to a history of headache, snoring, asthma and allergies, or to gender or place of residence. Conclusion: Mucosal swelling in paranasal sinuses and in mastoid cells is a frequent incidental finding in children. Even major mucosal swelling in a paranasal sinus is not necessarily a sign of infection. In radiological reports the terms 'sinusitis' and 'mastoiditis' should therefore be used with great caution. The initiation of treatment should be based on clinical symptoms and not on radiological abnormalities alone. (orig.)

  2. Ectopic adrenal tissue of spermatic cord in a 3- year- old boy, an incidental finding during orchidopexy: A case report

    Directory of Open Access Journals (Sweden)

    Biserka Pigac

    2017-11-01

    Full Text Available Ectopic adrenal tissue is usually found in kidney and retroperitoneum, yet other locations are considered uncommon. Spermatic cord remains one of the sites where this entity is mostly incidentally found during surgical procedure in childhood. Macroscopically, it represents as yellowish, lipomatous nodule. We present a case of ectopic adrenal tissue of spermatic cord in a 3- year- old boy, found during orchidopexy of the right testicle. Histopathological analysis of the spermatic cord nodule revealed adrenal cortical tissue composed of zona fasciculata cells. Although usually being benign and asymptomatic, cases of hyperplasia, adenoma and carcinoma arising from ectopic adrenal tissue have been reported. Therefore, removal of this tissue, when detected, is recommended.

  3. CNVs affecting cancer predisposing genes (CPGs) detected as incidental findings in routine germline diagnostic chromosomal microarray (CMA) testing.

    Science.gov (United States)

    Innes, Josie; Reali, Lisa; Clayton-Smith, Jill; Hall, Georgina; Lim, Derek Hk; Burghel, George J; French, Kim; Khan, Unzela; Walker, Daniel; Lalloo, Fiona; Evans, D Gareth R; McMullan, Dominic; Maher, Eamonn R; Woodward, Emma R

    2018-02-01

    Identification of CNVs through chromosomal microarray (CMA) testing is the first-line investigation in individuals with learning difficulties/congenital abnormalities. Although recognised that CMA testing may identify CNVs encompassing a cancer predisposition gene (CPG), limited information is available on the frequency and nature of such results. We investigated CNV gains and losses affecting 39 CPGs in 3366 pilot index case individuals undergoing CMA testing, and then studied an extended cohort (n=10 454) for CNV losses at 105 CPGs and CNV gains at 9 proto-oncogenes implicated in inherited cancer susceptibility. In the pilot cohort, 31/3366 (0.92%) individuals had a CNV involving one or more of 16/39 CPGs. 30/31 CNVs involved a tumour suppressor gene (TSG), and 1/30 a proto-oncogene (gain of MET ). BMPR1A , TSC2 and TMEM127 were affected in multiple cases. In the second stage analysis, 49/10 454 (0.47%) individuals in the extended cohort had 50 CNVs involving 24/105 CPGs. 43/50 CNVs involved a TSG and 7/50 a proto-oncogene (4 gains, 3 deletions). The most frequently involved genes, FLCN (n=10) and SDHA (n=7), map to the Smith-Magenis and cri-du-chat regions, respectively. Incidental identification of a CNV involving a CPG is not rare and poses challenges for future cancer risk estimation. Prospective data collection from CPG-CNV cohorts ascertained incidentally and through syndromic presentations is required to determine the risks posed by specific CNVs. In particular, ascertainment and investigation of adults with CPG-CNVs and adults with learning disability and cancer, could provide important information to guide clinical management and surveillance. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  4. LCA profiles for building components:

    DEFF Research Database (Denmark)

    Marsh, Rob

    2016-01-01

    . A full bivariate linear regression analysis is performed, showing statistically significant correlations with strong direct relationships between environmental impact categories. A simplified LCA profile consisting of total primary energy, global warming potential and acidification potential is developed...

  5. Incidental findings in paranasal sinuses and mastoid cells. A cross-sectional magnetic resonance imaging (MRI) study in a pediatric radiology department

    Energy Technology Data Exchange (ETDEWEB)

    Kalle, T. von; Fabig-Moritz, C.; Winkler, P. [Olgahospital Klinikum, Stuttgart (Germany). Radiologie; Heumann, H. [Olgahospital Klinikum, Stuttgart (Germany). Paediatrische HNO-Heilkunde und Otologie

    2012-07-15

    Purpose: Misdiagnosis of 'sinusitis' is still frequent in children, although mucosal swelling in the paranasal sinuses of children has been reported as a common incidental finding. Recent radiological publications on the problem are rare. We prospectively evaluated the mucosal thickening in the paranasal sinuses and mastoid cells of children who underwent MRI of the head for reasons other than sinusitis or mastoiditis. Materials and Methods: 147 patients, 0.2 - 22.7 years, median 8.9. Axial and sagittal T2 TSE images were evaluated by two experienced pediatric radiologists. Categories for the degree of mucosal swelling were for the maxillary, frontal and sphenoid sinuses: no swelling, minor: < 5 mm, or major: {>=} 5 mm; for ethmoid cells and mastoid cells: not present, minor: {<=} 50 % of cells, or major: > 50 %. Results: 61 % of children had one or more salient findings in their paranasal sinuses or mastoid cells. 48 % had mucosal swelling in their paranasal cavities, 25 % in their mastoid cells. The prevalence was higher among children less than 10 years of age (60 % and 42 %) and among children with current upper respiratory tract infection (71 % and 35 %). There was no correlation to a history of headache, snoring, asthma and allergies, or to gender or place of residence. Conclusion: Mucosal swelling in paranasal sinuses and in mastoid cells is a frequent incidental finding in children. Even major mucosal swelling in a paranasal sinus is not necessarily a sign of infection. In radiological reports the terms 'sinusitis' and 'mastoiditis' should therefore be used with great caution. The initiation of treatment should be based on clinical symptoms and not on radiological abnormalities alone. (orig.)

  6. Cradle to Cradle and LCA

    DEFF Research Database (Denmark)

    Bjørn, Anders; Hauschild, Michael Z.

    2018-01-01

    with the circular economy , the C2C certification and examples of C2C certified or inspired products and systems. This is followed by a comparison of C2C with eco-efficiency and LCA . Because of their important differences, we conclude that care should be taken when combing C2C and LCA, e.g. using LCA to evaluate......Cradle to Cradle (C2C) offers a positive vision of a future, where products are radically redesigned to be beneficial to humans and the environment. The idea is not to reduce negative impacts (as in LCA), but to increase positive impacts . This chapter presents the C2C concept and its relationship...... products inspired by C2C. We then provide an in-depth analysis of the conflicts between C2C and LCA and offer solutions. Finally, we reflect upon how LCA practitioners can learn from C2C in terms of providing a vision of a sustainable future, creating a sense of urgency for change and communicating results...

  7. LCA of Soil and Groundwater Remediation

    DEFF Research Database (Denmark)

    Søndergaard, Gitte Lemming; Owsianiak, Mikolaj

    2018-01-01

    Today, there is increasing interest in applying LCA to support decision-makers in contaminated site management. In this chapter, we introduce remediation technologies and associated environmental impacts, present an overview of literature findings on LCA applied to remediation technologies...... and present methodological issues to consider when conducting LCAs within the area. Within the field of contaminated site remediation , a terminology distinguishing three types of environmental impacts: primary, secondary and tertiary, is often applied. Primary impacts are the site-related impacts due...... and efficiency of remediation, which are important for assessment or primary impacts; (ii) robust assessment of primary impacts using site-specific fate and exposure models; (iii) weighting of primary and secondary (or tertiary) impacts to evaluate trade-offs between life cycle impacts from remediation...

  8. MIBI Tc-99m uptake due to breast cancer recurrence as an incidental finding in a patient with atypical chest pain

    International Nuclear Information System (INIS)

    Saavedra, P.; Cano, R.; Morales, R.; Urquiaga, J.; Negron, S.; Munoz, L.; Aguilar, C.; Mendoza, G.; Lopez, D.; Carlos, I.

    2005-01-01

    The purpose of this paper is lo report incidental findings of uptake of Tc99m-MIBI in anterior chest in a patient evaluated for a typical chest pain. A retrospective data collection was performed through chart review of the patient, a 67 year-old women, who had atypical chest pain with cardiac risk factors (hypertension, obesity, hypercholesterolemia, diabetes) with history of left total mastectomy (1995) without adjuvant chemotherapy and negative follow-up. Myocardial Perfusion imaging with Tc99m-MIBI was normal and showed uptake in anterior left chest in sagital views, described as suspected recurrent breast cancer. Oncological and cardiological evaluation of the patient was done and detected minimal palpable lesion in the surgery scar. Incisional biopsy of the lump in the surgery scar was positive for Infiltrative Ductal Breast Carcinoma. Tc-99m-MIBI is useful for detection of recurrence of breast carcinoma in surgery scar

  9. Striated nephrogram as an incidental finding in MRI examination of children; Streifiges Nephrogramm als Zufallsbefund nach Kontrastmittelgabe bei Kindern in der MRT

    Energy Technology Data Exchange (ETDEWEB)

    Strocka, S.; Sorge, I.; Ritter, L.; Hirsch, F.W. [Leipzig Univ. (Germany). Dept. of Pediatric Radiology

    2016-01-15

    A highly striated contrast pattern of the kidneys occasionally appears in abdominal MRI examinations of children following the administration of gadolinium. As this phenomenon is well known but has not yet been explicitly described in literature, we investigated how frequently and in which clinical context this occurred. 855 abdominal MRI examinations with contrast media of 362 children between 2006 and 2014 were analysed retrospectively. A striated renal parenchyma was found in a total of nine children and eleven examinations (1.3 % of examinations) and did only occur at a field strength of 3 Tesla. Of these children, seven had previously had tumors and chemotherapy. In two children there was no evidence of a previously serious condition with medications or a kidney disease. All of them had a normal renal function. A noticeably striated nephrogram in the later phase of an MRI examination following administration of gadolinium may appear as an incidental finding in examinations at 3 Tesla without pathological relevance.

  10. Involvement of LCA5 in Leber congenital amaurosis and retinitis pigmentosa in the Spanish population.

    Science.gov (United States)

    Corton, Marta; Avila-Fernandez, Almudena; Vallespín, Elena; López-Molina, María Isabel; Almoguera, Berta; Martín-Garrido, Esther; Tatu, Sorina D; Khan, M Imran; Blanco-Kelly, Fiona; Riveiro-Alvarez, Rosa; Brión, María; García-Sandoval, Blanca; Cremers, Frans P M; Carracedo, Angel; Ayuso, Carmen

    2014-01-01

    We aimed to identify novel genetic defects in the LCA5 gene underlying Leber congenital amaurosis (LCA) in the Spanish population and to describe the associated phenotype. Case series. A cohort of 217 unrelated Spanish families affected by autosomal recessive or isolated retinal dystrophy, that is, 79 families with LCA and 138 families with early-onset retinitis pigmentosa (EORP). A total of 100 healthy, unrelated Spanish individuals were screened as controls. High-resolution homozygosity mapping was performed in 44 patients with LCA using genome-wide single nucleotide polymorphism (SNP) microarrays. Direct sequencing of the LCA5 gene was performed in 5 patients who showed homozygous regions at chromosome 6 and in 173 unrelated individuals with LCA or EORP. The ophthalmic history of 8 patients carrying LCA5 mutations was reviewed and additional examinations were performed, including electroretinography (ERG), optical coherence tomography (OCT), and fundus photography. Single nucleotide polymorphism genotyping, identity-by-descent (IBD) regions, LCA5 mutations, best-corrected visual acuity, visual field assessments, fundus appearance, ERG, and OCT findings. Four novel and 2 previously reported LCA5 mutations have been identified in 6 unrelated families with LCA by homozygosity mapping or Sanger sequencing. Thus, LCA5 mutations have a frequency of 7.6% in the Spanish population. However, no LCA5 mutations were found in 138 patients with EORP. Although most of the identified LCA5 mutations led to a truncated protein, a likely pathogenic missense variant was identified for the first time as a cause of LCA, segregating in 2 families. We also have characterized a novel splicing site mutation at the RNA level, demonstrating that the mutant LCA5 transcript was absent in a patient. All patients carrying LCA5 mutations presented nystagmus, night blindness, and progressive loss of visual acuity and visual field leading to blindness toward the third decade of life. Fundoscopy

  11. Neglectable benefit of searching for incidental findings in the Dutch-Belgian lung cancer screening trial (NELSON) using low-dose multidetector CT

    International Nuclear Information System (INIS)

    Wiel, J.C.M. van de; Wang, Y.; Xu, D.M.; Zaag-Loonen, H.J. van der; Jagt, E.J. van der; Oudkerk, M.; Klaveren, R.J. van

    2007-01-01

    The purpose of this study was to prospectively determine the frequency and spectrum of incidental findings (IFs) and their clinical implications in a high risk population for lung cancer undergoing low-dose multidetector computed tomography (MDCT) screening for lung cancer. Scans of 1,929 participants were evaluated for lung lesions and IFs by two radiologists. IFs were categorised as not clinically relevant or possibly clinically relevant. Findings were considered possibly clinically relevant if they could require further evaluation or could have substantial clinical implications. All possibly clinically relevant IFs were reviewed by a third radiologist, who determined its clinical relevance. Of all 1,929 participants, 1,410 (73%) had not clinically relevant IFs and 163 (8%) had possibly clinically relevant IFs of which 129 (79%) were indeed considered clinically relevant. Additional imaging was performed mainly by ultrasound (112 of 118, 96%). All but one lesion were concluded to be benign, mostly cysts (n = 115, 80%). Only 21 (1%) participants had findings with clinical implications. In one participant a malignancy was found, yet without any clinical benefit since no curative treatment was possible. Based on our results, we advise against systematically searching for and reporting of IFs in lung cancer screening studies using low-dose MDCT. (orig.)

  12. Incidentally detected non-palpable testicular tumours in adults at scrotal ultrasound: impact of radiological findings on management Radiologic review and recommendations of the ESUR scrotal imaging subcommittee

    International Nuclear Information System (INIS)

    Rocher, Laurence; Ramchandani, Parvati; Belfield, Jane; Bertolotto, Michele; Derchi, Lorenzo E.; Correas, Jean Michel; Oyen, Raymond; Tsili, Athina C.; Turgut, Ahmet Tuncay; Dogra, Vikram; Fizazi, Karim; Freeman, Simon; Richenberg, Jonathan

    2016-01-01

    The increasing detection of small testicular lesions by ultrasound (US) in adults can lead to unnecessary orchiectomies. This article describes their nature, reviews the available literature on this subject and illustrates some classical lesions. We also suggest recommendations to help characterization and management. The ESUR scrotal imaging subcommittee searched for original and review articles published before May 2015 using the Pubmed and Medline databases. Key words used were 'testicular ultrasound', 'contrast-enhanced sonography', 'sonoelastography', 'magnetic resonance imaging', 'testis-sparing surgery', 'testis imaging', 'Leydig cell tumour', 'testicular cyst'. Consensus was obtained amongst the members of the subcommittee, urologist and medical oncologist. Simple cysts are frequent and benign, and do not require follow up or surgery. Incidentally discovered small solid testicular lesions detected are benign in up to 80 %, with Leydig cell tumours being the most frequent. However, the presence of microliths, macrocalcifications and hypoechoic areas surrounding the nodule are findings suggestive of malignant disease. Asymptomatic small testicular lesions found on ultrasound are mainly benign, but findings such as microliths or hypoechoic regions surrounding the nodules may indicate malignancy. Colour Doppler US remains the basic examination for characterization. The role of newer imaging modalities in characterization is evolving. (orig.)

  13. LCA of Biofuels and Biomaterials

    DEFF Research Database (Denmark)

    Hjuler, Susanne Vedel; Hansen, Sune Balle

    2018-01-01

    , the potential of bio-products as substitutes for fossil-based products is receiving much attention. According to many LCA studies, bio-products are environmentally superior to fossil products in some life cycle impact categories, while the picture is often opposite in others. Bio-products is a highly diverse...

  14. Antifreeze life cycle assessment (LCA

    Directory of Open Access Journals (Sweden)

    Kesić Jelena

    2005-01-01

    Full Text Available Antifreeze based on ethylene glycol is a commonly used commercial product The classification of ethylene glycol as a toxic material increased the disposal costs for used antifreeze and life cycle assessment became a necessity. Life Cycle Assessment (LCA considers the identification and quantification of raw materials and energy inputs and waste outputs during the whole life cycle of the analyzed product. The objectives of LCA are the evaluation of impacts on the environment and improvements of processes in order to reduce and/or eliminate waste. LCA is conducted through a mathematical model derived from mass and energy balances of all the processes included in the life cycle. In all energy processes the part of energy that can be transformed into some other kind of energy is called exergy. The concept of exergy considers the quality of different types of energy and the quality of different materials. It is also a connection between energy and mass transformations. The whole life cycle can be described by the value of the total loss of exergy. The physical meaning of this value is the loss of material and energy that can be used. The results of LCA are very useful for the analyzed products and processes and for the determined conditions under which the analysis was conducted. The results of this study indicate that recycling is the most satisfactory solution for the treatment of used antifreeze regarding material and energy consumption but the re-use of antifreeze should not be neglected as a solution.

  15. Globalisation and Mainstreaming of LCA

    DEFF Research Database (Denmark)

    Wangel, Arne

    2018-01-01

    The chapter describes how a globalised economy exacerbates the need of a mainstreaming of LCA, in particular the emergence of long, complex and geographically highly dispersed global value chains (GVCs). In documenting the three phases of the UNEP-SETAC Life Cycle Initiative, a conventional roadmap...

  16. LCA of a washing machine

    DEFF Research Database (Denmark)

    Erichsen, Hanne K. Linnet

    1997-01-01

    Task 2.1 has the aim to generate inforamtion of the present situation for electrical motors through life cycle assessment (LCA). When assessing the environmental burdens through out the life cycle of the motor it is necessary to look at the life cycle of the product in which the motor is used...

  17. Retained Intra-Abdominal Surgical Clamp Complicating Emergency Laparotomy: Incidental Finding on Hysterosalpingogram for Evaluation of Tubal Infertility

    Directory of Open Access Journals (Sweden)

    Adebiyi Gbadebo Adesiyun

    2014-01-01

    Full Text Available The finding of intraperitoneal foreign body complicating surgical intervention broadly remains as an issue of safety in the operative room, a source of emotive concern for the patient, and an upsetting but equally embarrassing situation to the surgeon and the team. However, in the media world, it is a source of sumptuous and captivating headline on the newspaper and to the legal profession, an attractive case to prosecute. A middle age teacher presented with secondary infertility. She had emergency laparotomy fifteen years ago for ruptured tubal ectopic pregnancy in a private hospital and postoperative period was uneventful. Amongst other investigations to find out the cause of infertility, she had hysterosalpingography and a radio-opaque clamp was visualized on the films. She was counselled and had laparotomy. A pair of surgical Kocher clamps was retrieved buried in the mesentery.

  18. Attributional and consequential LCA of milk production

    NARCIS (Netherlands)

    Thomassen, M.A.; Dalgaard, P.; Heijungs, R.; Boer, de I.J.M.

    2008-01-01

    Background, aim and scope Different ways of performing a life cycle assessment (LCA) are used to assess the environmental burden of milk production. A strong connection exists between the choice between attributional LCA (ALCA) and consequential LCA (CLCA) and the choice of how to handle

  19. Attributional and consequential LCA of milk production

    NARCIS (Netherlands)

    Thomassen, Marlies A.; Dalgaard, Randi; Heijungs, Reinout; De Boer, Imke

    Background, aim and scope: Different ways of performing a life cycle assessment (LCA) are used to assess the environmental burden of milk production. A strong connection exists between the choice between attributional LCA (ALCA) and consequential LCA (CLCA) and the choice of how to handle

  20. Acute suppurative appendicitis associated with Enterobius vermicularis: an incidental finding or a causative agent? A case report.

    Science.gov (United States)

    Efared, Boubacar; Atsame-Ebang, Gabrielle; Soumana, Boubacar Marou; Tahiri, Layla; Hammas, Nawal; El Fatemi, Hinde; Chbani, Laila

    2017-10-06

    Histological acute appendicitis patterns associated with Enterobius vermicularis is an extremely rare finding. The exact role of this parasite in acute appendicitis is controversial as usually resected specimens show no evidence of histological inflammation. We present herein a case of a 21-year-old male Arabic patient who presented with clinical syndrome of acute appendicitis. Emergency appendectomy was performed and the histopathological examination of the resected specimen showed the presence of E. vermicularis as well as intense acute inflammatory patterns such as mucosal ulceration and suppurative necrosis. The post-operative course was uneventful and the patient was discharged with appropriate anti-helmintic drug prescription. Acute appendicitis due to E. vermicularis is a very rare occurrence. The histopathological analysis of resected specimens should pay special attention to search for this parasite for adequate post-operative treatment of patients.

  1. Incidental Anatomic Finding of Celiacomesenteric Trunk Associated with ‘Nutcracker Phenomenon,’ or Compression of the Left Renal Vein

    Science.gov (United States)

    Peterson, Joshua; Hage, Anthony N.; Diljak, Stephan; Long, Benjamin D.; Marcusa, Daniel P.; Brzezinski, David W.; Eliason, Jonathan

    2017-01-01

    Patient: Female, 91 Final Diagnosis: Nutcracker syndrome • celiacomesenteric trunk Symptoms: Dyspepsia • dysphagia Medication: — Clinical Procedure: — Specialty: Surgery Objective: Congenital defects/diseases Background: Celiacomesenteric trunk (CMT) is a very rare anatomic finding in which the celiac artery and the superior mesenteric artery (SMA) originate from the abdominal aorta through a common trunk. Clinical associations with CMT include arterial aneurysm, thrombosis, and celiac artery compression. However, an association between CMT and abdominal venous congestion caused by left renal vein compression, or ‘nutcracker phenomenon,’ has not been previously reported. Case Report: A 91-year-old woman, who died from a cerebrovascular accident (CVA), underwent a cadaveric examination at our medical school. On examination of the abdomen, there was an incidental finding of CMT. The arterial and venous diameters were measured, and vascular histopathology was undertaken. The vascular anatomy was consistent with CMT type 1-b. Nutcracker phenomenon (NCP) (left renal vein compression) was seen anatomically as dilatation and engorgement of the left renal vein, relative to the right renal vein (10.77±0.13 mm vs. 4.49±0.56 mm, respectively), and dilatation and engorgement of the left ovarian vein, relative to the right ovarian vein (4.37±0.15 mm vs. 1.06±0.09 mm, respectively) with left ovarian varicocele. The aortoceliac angle (ACA) and the aortomesenteric angle (AMA) approached zero degrees. Conclusions: We have described a rare anatomic finding of CMT that created an acute AMA and NCP. Awareness of this rare association between CMT and NCP by clinicians, vascular surgeons, and radiologists may be of value in the future evaluation and surgical management of patients who present clinically with ‘nutcracker syndrome.’ PMID:29242494

  2. Incidental findings of the kidneys, adrenal glands, adnexa uteri, gastrointestinal tract, mesentery and lymph nodes. Assessment and management recommendations; Zufallsbefunde von Niere, Nebenniere, Adnexen, Gastrointestinaltrakt, Mesenterium und Lymphknoten. Bewertung und Managementempfehlung

    Energy Technology Data Exchange (ETDEWEB)

    Scharitzer, M.; Tamandl, D.; Ba-Ssalamah, A. [Medizinische Universitaet Wien, Universitaetsklinik fuer Radiologie und Nuklearmedizin, Wien (Austria)

    2017-04-15

    Besides the upper abdominal parenchymal organs, the increasing application of cross-sectional imaging has also led to a rising number of incidental findings in the kidneys, adrenal glands, adnexa uteri, the gastrointestinal tract, mesentery and abdominal lymph nodes. Abdominal computed tomography investigations often show unexpected findings without any correlating symptoms. The growing clinical relevance is due to the large number of incidental findings as well as an increasing awareness of ethical and socioeconomic factors. When interpreting radiological findings not only morphological criteria but also individual risk factors of the patient and the clinical context are of great importance. The aims of this article are the description and evaluation of frequent incidental findings detected by computed tomography and to provide information about management recommendations. (orig.) [German] Neben den parenchymatoesen Oberbauchorganen hat der zunehmende Einsatz von Schnittbildverfahren zu einer vermehrten Anzahl von Zufallsbefunden der Nieren, Nebennieren, Adnexe, des Gastrointestinaltrakts, Mesenteriums und der intraabdominellen Lymphknoten gefuehrt. Abdominelle CT-Untersuchungen zeigen haeufig unerwartete Befunde ohne korrelierende Symptomatik. Die steigende klinische Relevanz ist einerseits auf die Zunahme inzidenteller Pathologien und andererseits auf ein wachsendes Bewusstsein ethischer und soziooekonomischer Faktoren zurueckzufuehren. Bei der radiologischen Interpretation sind neben morphologischen Kriterien sowohl die Einbeziehung der individuellen Risikofaktoren des Patienten als auch der klinische Gesamtkontext von grosser Bedeutung. Das Ziel dieses Artikels ist eine Beschreibung und Bewertung der in der Computertomographie detektierten genannten Zufallsbefunde sowie weiterer Managementempfehlungen. (orig.)

  3. Incidental versus non-incidental thyroid carcinoma: Clinical presentation, surgical management and prognosis.

    Science.gov (United States)

    González-Sánchez-Migallón, Elena; Flores-Pastor, Benito; Pérez-Guarinos, Carmen Victoria; Miguel-Perelló, Joana; Chaves-Benito, Asunción; Illán-Gómez, Fátima; Carrillo-Alcaraz, Andrés; Aguayo-Albasini, José Luis

    2016-11-01

    Thyroid cancer may be clinically evident as a tumor mass in the neck or as a histopathological incidental finding after thyroid surgery for an apparent benign condition. Our objective was to assess the differences in clinical signs, surgical management, and course between incidental and clinically diagnosed thyroid tumors. A retrospective study was conducted on patients operated on for benign or malignant thyroid disease from January 2000 to March 2014. Among the 1415 patients who underwent any thyroid surgery, 264 neoplasms were found, of which 170 were incidental. A comparison was made of incidental versus non-incidental carcinomas. Among incidental carcinomas, cases whose indication for surgery was Graves' disease were compared to those with multinodular goiter. Incidental carcinomas were in earlier stages and required less aggressive surgery. There were no differences in surgical complications between incidental and clinical tumors, but mortality and relapses were markedly higher in non-incidental cancers (4.4% vs 0% and 13.2% vs 4.8% respectively). Carcinomas developing on Graves' disease showed no differences from all other incidental tumors in terms of complications, mortality, or relapse after surgery. Early stage thyroid cancer has better survival and prognosis after surgical treatment. Copyright © 2016 SEEN. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Review of LCA studies of solid waste management systems – Part I: Lessons learned and perspectives

    International Nuclear Information System (INIS)

    Laurent, Alexis; Bakas, Ioannis; Clavreul, Julie; Bernstad, Anna; Niero, Monia; Gentil, Emmanuel; Hauschild, Michael Z.; Christensen, Thomas H.

    2014-01-01

    Highlights: • We perform a critical review of 222 LCA studies of solid waste management systems. • Studies mainly concentrated in Europe with little application in developing countries. • Assessments of relevant waste types apart from household waste have been overlooked. • Local specificities of systems prevent a meaningful generalisation of the LCA results. • LCA should support recommendations representative of the local conditions. - Abstract: The continuously increasing solid waste generation worldwide calls for management strategies that integrate concerns for environmental sustainability. By quantifying environmental impacts of systems, life cycle assessment (LCA) is a tool, which can contribute to answer that call. But how, where and to which extent has it been applied to solid waste management systems (SWMSs) until now, and which lessons can be learnt from the findings of these LCA applications? To address these questions, we performed a critical review of 222 published LCA studies of SWMS. We first analysed the geographic distribution and found that the published studies have primarily been concentrated in Europe with little application in developing countries. In terms of technological coverage, they have largely overlooked application of LCA to waste prevention activities and to relevant waste types apart from household waste, e.g. construction and demolition waste. Waste management practitioners are thus encouraged to abridge these gaps in future applications of LCA. In addition to this contextual analysis, we also evaluated the findings of selected studies of good quality and found that there is little agreement in the conclusions among them. The strong dependence of each SWMS on local conditions, such as waste composition or energy system, prevents a meaningful generalisation of the LCA results as we find it in the waste hierarchy. We therefore recommend stakeholders in solid waste management to regard LCA as a tool, which, by its ability of

  5. Review of LCA studies of solid waste management systems – Part I: Lessons learned and perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Laurent, Alexis, E-mail: alau@dtu.dk [Division for Quantitative Sustainability Assessment, Department of Management Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); Bakas, Ioannis [Division for Quantitative Sustainability Assessment, Department of Management Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); Clavreul, Julie [Residual Resources Engineering, Department of Environmental Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); Bernstad, Anna [Water and Environmental Engineering, Department of Chemical Engineering, Lund University, 221 00 Lund (Sweden); Niero, Monia [Division for Quantitative Sustainability Assessment, Department of Management Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); ECO – Ecosystems and Environmental Sustainability, Department of Chemical and Biochemical Engineering, Technical University of Denmark, 4000 Roskilde (Denmark); Gentil, Emmanuel [Copenhagen Resource Institute, 1215 Copenhagen K (Denmark); Hauschild, Michael Z. [Division for Quantitative Sustainability Assessment, Department of Management Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); Christensen, Thomas H. [Residual Resources Engineering, Department of Environmental Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark)

    2014-03-01

    Highlights: • We perform a critical review of 222 LCA studies of solid waste management systems. • Studies mainly concentrated in Europe with little application in developing countries. • Assessments of relevant waste types apart from household waste have been overlooked. • Local specificities of systems prevent a meaningful generalisation of the LCA results. • LCA should support recommendations representative of the local conditions. - Abstract: The continuously increasing solid waste generation worldwide calls for management strategies that integrate concerns for environmental sustainability. By quantifying environmental impacts of systems, life cycle assessment (LCA) is a tool, which can contribute to answer that call. But how, where and to which extent has it been applied to solid waste management systems (SWMSs) until now, and which lessons can be learnt from the findings of these LCA applications? To address these questions, we performed a critical review of 222 published LCA studies of SWMS. We first analysed the geographic distribution and found that the published studies have primarily been concentrated in Europe with little application in developing countries. In terms of technological coverage, they have largely overlooked application of LCA to waste prevention activities and to relevant waste types apart from household waste, e.g. construction and demolition waste. Waste management practitioners are thus encouraged to abridge these gaps in future applications of LCA. In addition to this contextual analysis, we also evaluated the findings of selected studies of good quality and found that there is little agreement in the conclusions among them. The strong dependence of each SWMS on local conditions, such as waste composition or energy system, prevents a meaningful generalisation of the LCA results as we find it in the waste hierarchy. We therefore recommend stakeholders in solid waste management to regard LCA as a tool, which, by its ability of

  6. USEEIOv1.1 - openLCA

    Data.gov (United States)

    U.S. Environmental Protection Agency — This is a version of the full USEEIO v1.1 model in the openLCA schema serialized as JSON-LD that can be imported into openLCA software (www.openlca.org) v1.5 and...

  7. Temporal Considerations of Carbon Sequestration in LCA

    Science.gov (United States)

    James Salazar; Richard Bergman

    2013-01-01

    Accounting for carbon sequestration in LCA illustrates the limitations of a single global warming characterization factor. Typical cradle-to-grave LCA models all emissions from end-of-life processes and then characterizes these flows by IPCC GWP (100-yr) factors. A novel method estimates climate change impact by characterizing annual emissions with the IPCC GHG forcing...

  8. Transportation Life Cycle Assessment (LCA) Synthesis, Phase II

    Science.gov (United States)

    2018-04-24

    The Transportation Life Cycle Assessment (LCA) Synthesis includes an LCA Learning Module Series, case studies, and analytics on the use of the modules. The module series is a set of narrated slideshows on topics related to environmental LCA. Phase I ...

  9. LCA versus RA - an introduction

    DEFF Research Database (Denmark)

    Olsen, Stig Irving

    2000-01-01

    Risk Assessment (RA) of chemicals is an environmental management tool used to assess the risk of specific chemicals, which are harmful to man or the environment under certain circumstances of use or in certain environmental recipients. Life Cycle Assessment (LCA) or environmental assessment...... of Industrial Products) developed in Denmark (Wenzel et al., 1997), respectively. The interactions between the two tools can be viewed from two different angles: 1. As a general reflection of how the tools supplement each other in the total environmental effort. 2. As an assessment of coincidences...... on Principles and Methods for Hazard and Risk Assessment)focuses on an assessment of the toxicological and ecotoxicological risks, the focus of this article's comparison of assessment principles, data requirements etc. will be on the assessment of toxicity and ecotoxicity in EDIP's impact assessment methodology...

  10. LCA of Food and Agriculture

    DEFF Research Database (Denmark)

    Dijkman, Teunis Johannes; Basset-Mens, Claudine; Antón, Assumpció

    2018-01-01

    , preparation and waste of the food. In the waste management stage, food waste can be handled using a number of technologies, such as landfilling, incineration , composting or digestion. A number of case studies are looked at here where the life cycles of typical food products (meat , cheese, bread, tomatoes......This chapter deals with the application of Life Cycle Assessment to evaluate the environmental sustainability of agriculture and food processing. The life cycle of a food product is split into six stages: production and transportation of inputs to the farm, cultivation, processing, distribution...... , consumption and waste management . A large number of LCA studies focus on the two first stages in cradle-to-farm gate studies, as they are the stages where most impacts typically occur, due to animal husbandry and manure handling, production and use of fertilisers and the consumption of fuel to operate farm...

  11. Incidental Vocabulary Learning in Second Language Acquisition: A Literature Review

    Directory of Open Access Journals (Sweden)

    Falcon Dario Restrepo Ramos

    2015-01-01

    Full Text Available This literature review aims to analyze previous studies that address the incidental learning of vocabulary in second language acquisition. The articles included in this literature review look into the understanding of vocabulary learning through incidental means, the relationship of reading and incidental vocabulary learning, and the strategies and tasks that promote the incidental learning of vocabulary. The findings show that L2 learners develop much of their vocabulary by incidental means through exposure to words in informative contexts. Moreover, this exposure is promoted by reading, and enhanced through multimodal glosses. Further research may focus on listening for higher lexical retention rates, the circumstances that allow incidental learning of multi-word phrases and collocations, and the use of technology-based methods for incidental vocabulary acquisition.

  12. LCA of Solid Waste Management Systems

    DEFF Research Database (Denmark)

    Bakas, Ioannis; Laurent, Alexis; Clavreul, Julie

    2018-01-01

    The chapter explores the application of LCA to solid waste management systems through the review of published studies on the subject. The environmental implications of choices involved in the modelling setup of waste management systems are increasingly in the spotlight, due to public health...... concerns and new legislation addressing the impacts from managing our waste. The application of LCA to solid waste management systems, sometimes called “waste LCA”, is distinctive in that system boundaries are rigorously defined to exclude all life cycle stages except from the end-of-life. Moreover...... LCA on solid waste systems....

  13. Mapping and characterization of LCA networks

    DEFF Research Database (Denmark)

    Bjørn, Anders; Owsianiak, Mikolaj; Laurent, Alexis

    2013-01-01

    Purpose: The aims of this study were to provide an up-todate overview of global, regional and local networks supporting life cycle thinking and to characterize them according to their structure and activities. Methods: Following a tentative life cycle assessment (LCA) network definition, a mapping......: The provided list of LCA networks is currently the most comprehensive, publicly available mapping. We believe that the results of this mapping can serve as a basis for deciding where priorities should be set to increase the dissemination and development of LCA worldwide. In this aim, we also advocate...... was performed based on (1) a literature search, (2) a web search and (3) an inquiry to stakeholders distributed via the two largest LCA fora. Networks were characterized based on responses from a survey. Results and discussion: We identified 100 networks, of which 29 fulfilled all six criteria composing our...

  14. Implications of the Incidental Finding of a MYCN Amplified Adrenal Tumor: A Case Report and Update of a Pediatric Disease Diagnosed in Adults

    Directory of Open Access Journals (Sweden)

    Anna Koumarianou

    2013-01-01

    Full Text Available MYCN is a well-known oncogene overexpressed in different human malignancies including neuroblastoma, rhabdomyosarcoma, medulloblastoma, astrocytoma, Wilms’ tumor, and small cell lung cancer. While neuroblastoma is one of the most common childhood malignancies, in adults it is extremely rare and its treatment is based on pediatric protocols that take into consideration stage and genotypic features, such as MYCN amplification. Although neuroblastoma therapy has evolved, identification of early stage patients who need chemotherapy continues to pose a therapeutic challenge. The emerging prognostic role of MYCN phenotype of this disease is currently under investigation as it may redefine MYCN amplified subgroups. We describe an unusual case of adult neuroblastoma with MYCN amplification diagnosed incidentally and discuss possible therapeutic dilemmas.

  15. Review of LCA studies of solid waste management systems – Part I: Lessons learned and perspectives

    DEFF Research Database (Denmark)

    Laurent, Alexis; Bakas, Ioannis; Clavreul, Julie

    2014-01-01

    distribution and found that the published studies have primarily been concentrated in Europe with little application in developing countries. In terms of technological coverage, they have largely overlooked application of LCA to waste prevention activities and to relevant waste types apart from household waste......The continuously increasing solid waste generation worldwide calls for management strategies that integrate concerns for environmental sustainability. By quantifying environmental impacts of systems, life cycle assessment (LCA) is a tool, which can contribute to answer that call. But how, where...... and to which extent has it been applied to solid waste management systems (SWMSs) until now, and which lessons can be learnt from the findings of these LCA applications? To address these questions, we performed a critical review of 222 published LCA studies of SWMS. We first analysed the geographic...

  16. Achado incidental de glândula sebácea em colo uterino: provavelmente um processo metaplásico An incidental finding of sebaceous glands in the uterine cervix: a probable metaplastic process

    Directory of Open Access Journals (Sweden)

    Daniel Cury Ogata

    2012-06-01

    Full Text Available As glândulas sebáceas ectópicas são achados muito infrequentes no trato genital feminino. Descrevemos um caso que ocorreu em paciente de 42 anos de idade, submetida à histerectomia total, devido à leiomiomatose e ao prolapso uterino.The ectopic sebaceous glands have been extremely rare findings in female genital system. We describe the case of 42 years-old patient with total hysterectomy due to leiomyomatosis and uterine prolapsed.

  17. Incidental renal neoplasms

    DEFF Research Database (Denmark)

    Rabjerg, Maj; Mikkelsen, Minne Nedergaard; Walter, Steen

    2014-01-01

    On the basis of associations between tumor size, pathological stage, histological subtype and tumor grade in incidentally detected renal cell carcinoma vs symptomatic renal cell carcinoma, we discussed the need for a screening program of renal cell carcinoma in Denmark. We analyzed a consecutive...... series of 204 patients with renal tumors in 2011 and 2012. The tumors were classified according to detection mode: symptomatic and incidental and compared to pathological parameters. Eighty-nine patients (44%) were symptomatic, 113 (55%) were incidental. Information was not available in two patients...

  18. LCA of Chemicals and Chemical Products

    DEFF Research Database (Denmark)

    Fantke, Peter; Ernstoff, Alexi

    2018-01-01

    This chapter focuses on the application of Life Cycle Assessment (LCA) to evaluate the environmental performance of chemicals as well as of products and processes where chemicals play a key role. The life cycle stages of chemical products, such as pharmaceuticals drugs or plant protection products......, are discussed and differentiated into extraction of abiotic and biotic raw materials, chemical synthesis and processing, material processing, product manufacturing, professional or consumer product use, and finally end-of-life . LCA is discussed in relation to other chemicals management frameworks and concepts...... including risk assessment , green and sustainable chemistry , and chemical alternatives assessment. A large number of LCA studies focus on contrasting different feedstocks or chemical synthesis processes, thereby often conducting a cradle to (factory) gate assessment. While typically a large share...

  19. Attributional and consequential LCA of milk production

    DEFF Research Database (Denmark)

    Thomassen, Marlies A; Dalgaard, Randi; Heijungs, Reinout

    2008-01-01

    Background, aim and scope  Different ways of performing a life cycle assessment (LCA) are used to assess the environmental burden of milk production. A strong connection exists between the choice between attributional LCA (ALCA) and consequential LCA (CLCA) and the choice of how to handle co......-products. Insight is needed in the effect of choice on results of environmental analyses of agricultural products, such as milk. The main goal of this study was to demonstrate and compare ALCA and CLCA of an average conventional milk production system in The Netherlands. Materials and methods  ALCA describes...... the pollution and resource flows within a chosen system attributed to the delivery of a specified amount of the functional unit. CLCA estimates how pollution and resource flows within a system change in response to a change in output of the functional unit. For an average Dutch conventional milk production...

  20. Emerging role of Geographical Information System (GIS), Life Cycle Assessment (LCA) and spatial LCA (GIS-LCA) in sustainable bioenergy planning.

    Science.gov (United States)

    Hiloidhari, Moonmoon; Baruah, D C; Singh, Anoop; Kataki, Sampriti; Medhi, Kristina; Kumari, Shilpi; Ramachandra, T V; Jenkins, B M; Thakur, Indu Shekhar

    2017-10-01

    Sustainability of a bioenergy project depends on precise assessment of biomass resource, planning of cost-effective logistics and evaluation of possible environmental implications. In this context, this paper reviews the role and applications of geo-spatial tool such as Geographical Information System (GIS) for precise agro-residue resource assessment, biomass logistic and power plant design. Further, application of Life Cycle Assessment (LCA) in understanding the potential impact of agro-residue bioenergy generation on different ecosystem services has also been reviewed and limitations associated with LCA variability and uncertainty were discussed. Usefulness of integration of GIS into LCA (i.e. spatial LCA) to overcome the limitations of conventional LCA and to produce a holistic evaluation of the environmental benefits and concerns of bioenergy is also reviewed. Application of GIS, LCA and spatial LCA can help alleviate the challenges faced by ambitious bioenergy projects by addressing both economics and environmental goals. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Anticipate and communicate: Ethical management of incidental and secondary findings in the clinical, research, and direct-to-consumer contexts (December 2013 report of the Presidential Commission for the Study of Bioethical Issues).

    Science.gov (United States)

    Weiner, Christine

    2014-09-15

    Genomic population research increases the possibility of finding genetic coding anomalies that are not the primary object of research but may have significance for the current and future medical care of research participants and progeny. The December 2013 Report of the Presidential Commission for the Study of Bioethical Issues (Anticipate and Communicate: Ethical Management of Incidental and Secondary Findings in the Clinical, Research, and Direct-to-Consumer Contexts (http://bioethics.gov/sites/default/files/FINALAnticipateCommunicate_PCSBI_0.pdf)) recommends that a researcher anticipate these findings and make a plan that addresses which findings will be communicated to research participants and how. Following these recommendations will be disruptive for both investigators and institutional review boards (IRBs) until the research community reaches consensus, or a mechanism for evolving consensus, on which results should be returned to research participants. A protocol-by-protocol approach, though laborious, makes sense for both investigators and IRBs as the research community thinks through the implications of genomic research. Epidemiologists will note that discussion of the return of results and the plan for communicating findings should be included in both the participant consent agreement and the research protocol submitted to the IRB. © The Author 2014. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  2. Recent LCA Developments In Waste Management

    DEFF Research Database (Denmark)

    Christensen, Thomas Højlund; Astrup, Thomas Fruergaard; Brogaard, Line Kai-Sørensen

    2015-01-01

    Based on 10 years of experience we briefly present key issues which should receive special attention when waste LCA is performed. Attention paid to the importance of good data on waste composition, the contribution of environmental impacts from capital goods, assessing the value of recovered mate...

  3. Use of Input–Output Analysis in LCA

    DEFF Research Database (Denmark)

    Mattila, Tuomas J.

    2018-01-01

    Input–output analysis can be used as a tool for complementing the traditionally process-based life cycle assessment (LCA) with macroeconomic data from the background systems. Properly used, it can result in faster and more accurate LCA. It also provides opportunities for streamlining the LCA inve...

  4. Crane. Incidental Classroom Instruction 20295

    Energy Technology Data Exchange (ETDEWEB)

    Reynolds, Richard Jennings [Los Alamos National Laboratory

    2016-04-01

    The purpose of this course is to introduce safe hoisting and rigging practices to personnel who are attempting to become LANL incidental crane operators and to review and refresh safe hoisting and rigging practices with existing incidental crane operators.

  5. Negative incidental emotions augment fairness sensitivity.

    Science.gov (United States)

    Liu, Cuizhen; Chai, Jing Wen; Yu, Rongjun

    2016-04-22

    Previous studies have shown that task-unrelated emotions induced incidentally exert carryover effects on individuals' subsequent decisions in financial negotiations. However, the specificity of these emotion effects are not clear. In three experiments, we systematically investigated the role of seven transiently induced basic emotions (disgust, sadness, anger, fear, happiness, surprise and neutral) on rejection of unfair offers using the ultimatum game. We found that all negative emotions (disgust, sadness, anger and fear), but not happiness or surprise, significantly increased rejection rates, suggesting that the effect of incidental negative emotions on fairness is not specific to the type of negative emotion. Our findings highlight the role of fleeting emotions in biasing decision-making processes and suggest that all incidental negative emotions exert similar effects on fairness sensitivity, possibly by potentiating attention towards negative aspects of the situation.

  6. Incidental findings of liver, biliary system, pancreas and spleen in asymptomatic patients. Assessment and management recommendations; Zufallsbefunde von Leber, Gallensystem, Pankreas und Milz bei asymptomatischen Patienten. Bewertung und Managementempfehlung

    Energy Technology Data Exchange (ETDEWEB)

    Scharitzer, M.; Tamandl, D.; Ba-Ssalamah, A. [Medizinische Universitaet Wien, Universitaetsklinik fuer Radiologie und Nuklearmedizin, Wien (Austria)

    2017-04-15

    The increased use of highly developed imaging procedures, such as multidetector-row computed tomography and magnetic resonance imaging has led to a substantial increase of asymptomatic and unexpected findings. Abdominal CT investigations are particularly affected with a large number of incidental findings. This valuable diagnostic procedure also entails the risk of complex and cost-intensive subsequent investigations with partly invasive procedures. For this reason radiologists are more often confronted with the difficult task of correctly assessing these lesions, to decide on the need for additional investigations and to inform the patient in detail about the clinical relevance. The aims of this article are to describe the most common abdominal incidentalomas, to assist with the interpretation and differential diagnosis and to give recommendations for further management. (orig.) [German] Die vermehrte Verwendung hoch entwickelter bildgebender Verfahren wie Multidetektorcomputertomographie und Magnetresonanztomographie hat zu einer betraechtlichen Zunahme asymptomatischer und unerwarteter Befunde gefuehrt. Besonders betroffen sind abdominelle CT-Untersuchungen mit einer Vielzahl inzidenteller Befunde. Dieses wertvolle Diagnoseverfahren birgt auch die Gefahr aufwendiger und auch kostenintensiver Folgeuntersuchungen mit z. T. invasiven Verfahren. Vor diesem Hintergrund stellt sich fuer den Radiologen immer haeufiger die schwierige Aufgabe, diese Laesionen korrekt einzuschaetzen, ueber die Notwendigkeit einer weiteren Abklaerung zu entscheiden und den Patienten umfassend ueber die klinische Relevanz zu informieren. Das Ziel dieses Artikels ist es, die am haeufigsten vorkommenden abdominellen Zufallsbefunde zu beschreiben sowie Hilfestellung bei ihrer Interpretation und Differenzialdiagnose mit Empfehlungen fuer das weitere Management zu geben. (orig.)

  7. Panorama 2013 - Using LCA in selecting technologies

    International Nuclear Information System (INIS)

    Collet, Pierre

    2012-12-01

    Our society is increasingly concerned with safeguarding the environment. By assessing the impact that the manufacture of a product or the delivery of a service can have on the environment, Life-Cycle Assessment (LCA) can be used to identify key sources of pollution and possible ways of mitigating against it. The ways in which this tool can be used are demonstrated here by various projects which help define innovative energy production systems. (author)

  8. On process optimization considering LCA methodology.

    Science.gov (United States)

    Pieragostini, Carla; Mussati, Miguel C; Aguirre, Pío

    2012-04-15

    The goal of this work is to research the state-of-the-art in process optimization techniques and tools based on LCA, focused in the process engineering field. A collection of methods, approaches, applications, specific software packages, and insights regarding experiences and progress made in applying the LCA methodology coupled to optimization frameworks is provided, and general trends are identified. The "cradle-to-gate" concept to define the system boundaries is the most used approach in practice, instead of the "cradle-to-grave" approach. Normally, the relationship between inventory data and impact category indicators is linearly expressed by the characterization factors; then, synergic effects of the contaminants are neglected. Among the LCIA methods, the eco-indicator 99, which is based on the endpoint category and the panel method, is the most used in practice. A single environmental impact function, resulting from the aggregation of environmental impacts, is formulated as the environmental objective in most analyzed cases. SimaPro is the most used software for LCA applications in literature analyzed. The multi-objective optimization is the most used approach for dealing with this kind of problems, where the ε-constraint method for generating the Pareto set is the most applied technique. However, a renewed interest in formulating a single economic objective function in optimization frameworks can be observed, favored by the development of life cycle cost software and progress made in assessing costs of environmental externalities. Finally, a trend to deal with multi-period scenarios into integrated LCA-optimization frameworks can be distinguished providing more accurate results upon data availability. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Evaluation of environmental impact by LCA method. LCA shuho ni yoru kankyo fuka hyoka

    Energy Technology Data Exchange (ETDEWEB)

    Sakamura, H.; Utsuno, F.; Yasui, I. (The University of Tokyo, Tokyo (Japan). Institute of Industrial Science)

    1994-06-01

    This paper explains the concept, history, and analytic methods of life cycle assessment (LCA), showing its application to beer bottles and cement factories as specific examples. The LCA is a method to calculate substances and energies put into the whole process of production of a product from raw material mining to product wasting and environmental loads emitted therefrom. It also evaluates the result collectively and quantitatively. A first case of the research is reportedly the one performed at Coca-Cola Co., Ltd. in 1969. Full-scale researches have gone forward in European countries in the recent several years, and are progressing to international networks. The analytic methods can be divided largely into an accumulation method to analyze data in each process and add them up, and a method to use an industrial association table. The former method is the most generally used method currently in overseas countries if referred to the LCA. Because the LCA can cause the analytic result and evaluation to vary depending on the purpose, it is important to define the goal, and set the scope. The LCA must develop in the future although it has a number of problems. 10 refs., 5 figs., 2 tabs.

  10. Review of methodologies for Social LCA

    DEFF Research Database (Denmark)

    Jørgensen, Andreas; Hauschild, Michael Zwicky

    on their approaches to the goal and scope definition, inventory, and impact assessment phases of LCA. The review concludes that a main methodical difference lies in the definition of impact categories to be included in the assessment as well as in the formulation of indicators. Another challenging aspect is the data...... collection. Some SLCA proposals opinion that the use of generic process data is not feasible in SLCA, because social impacts are claimed not to be process specific but rather company specific. This change could easily imply a strong need for site-specific data leading to a very demanding data collection...

  11. Incidental fear cues increase monetary loss aversion.

    Science.gov (United States)

    Schulreich, Stefan; Gerhardt, Holger; Heekeren, Hauke R

    2016-04-01

    In many everyday decisions, people exhibit loss aversion-a greater sensitivity to losses relative to gains of equal size. Loss aversion is thought to be (at least partly) mediated by emotional--in particular, fear-related--processes. Decision research has shown that even incidental emotions, which are unrelated to the decision at hand, can influence decision making. The effect of incidental fear on loss aversion, however, is thus far unclear. In two studies, we experimentally investigated how incidental fear cues, presented during (Study 1) or before (Study 2) choices to accept or reject mixed gambles over real monetary stakes, influence monetary loss aversion. We find that the presentation of fearful faces, relative to the presentation of neutral faces, increased risk aversion-an effect that could be attributed to increased loss aversion. The size of this effect was moderated by psychopathic personality: Fearless dominance, in particular its interpersonal facet, but not self-centered impulsivity, attenuated the effect of incidental fear cues on loss aversion, consistent with reduced fear reactivity. Together, these results highlight the sensitivity of loss aversion to the affective context. (c) 2016 APA, all rights reserved).

  12. Quantifying uncertainty in LCA-modelling of waste management systems

    DEFF Research Database (Denmark)

    Clavreul, Julie; Guyonnet, D.; Christensen, Thomas Højlund

    2012-01-01

    Uncertainty analysis in LCA studies has been subject to major progress over the last years. In the context of waste management, various methods have been implemented but a systematic method for uncertainty analysis of waste-LCA studies is lacking. The objective of this paper is (1) to present...... the sources of uncertainty specifically inherent to waste-LCA studies, (2) to select and apply several methods for uncertainty analysis and (3) to develop a general framework for quantitative uncertainty assessment of LCA of waste management systems. The suggested method is a sequence of four steps combining...

  13. Survey on the Use of LCA in European Chemical Industry

    DEFF Research Database (Denmark)

    Olsen, Stig Irving

    1999-01-01

    During 1997 a questionnaire was sent to 40 European chemical manufacturers representing different positions in the supply chain. 25 companies (62.5%) responded, of which 23 had been involved in LCA to some degree. The questionnaire consisted of 30 questions divided into four parts dealing...... industry has taken up the LCA methodology and is testing its applicability for their purposes, although they still feel the methodology is a bit immature. The resources devoted to LCA depends to a great extent on the company's position in the supply chain and on the size of the company. Many of the LCA...

  14. Incidental Finding of Isolated Colonic Neurofibroma

    Directory of Open Access Journals (Sweden)

    Haritha Chelimilla

    2013-09-01

    Full Text Available Neurofibromatosis is a genetic disorder manifested by characteristic cutaneous lesions called neurofibromas. There are two distinct neurocutaneous syndromes named neurofibromatosis type 1 (also called von Recklinghausen disease or NF1 and neurofibromatosis type 2 (NF2. NF1 is by far the most common presentation and is caused by an autosomal dominant mutation in the NF1 gene mapped to chromosome 17q11.2. The literature shows that gastrointestinal involvement is noted in systemic neurofibromatosis in up to 25% of patients, but isolated intestinal neurofibromatosis is a very rare manifestation. We herein present the case of a 70-year-old woman who was diagnosed with an isolated colonic neurofibroma without any systemic signs of neurofibromatosis; only a few case reports of this condition have been published to date.

  15. Incidental finding of pheochromocytoma after imaging exam

    Directory of Open Access Journals (Sweden)

    Bianca Lara Teixeira

    2017-11-01

    Full Text Available Pheochromocytomas — 90% of those being benign — are relatively rare tumors of the adrenal medulla, catecholamines producers. About 75% of patients manifest the sudden classic triad characterized by severe hypertension, palpitations and headache. The diagnosis is confirmed by urinary metanephrines dosage, and radiological tests such as ultrasonography, computed tomography and magnetic resonance imaging. The curative treatment consists in removing the tumor, and videolaparoscopy is the chosen surgical technique. This report describes the case of a woman, who sought the emergency unit complaining of left back, and after imaging tests, was evidenced a large adrenal mass. The patient presented as a symptom linked to the secreting tumor was only secondary hypertension. It was opted to perform an open surgery as a consequence of the tumor dimensions, and the person presents herself normotensive after left adrenectomy.

  16. Autosomal Dominant Polycystic Kidney Disease, incidental finding ...

    African Journals Online (AJOL)

    N.J. Gildenhuys

    2016-06-30

    Jun 30, 2016 ... This case study serves as a learning opportunity and future reference in the cases and management of ... sentation, special investigations, and treatment. The table ... trauma to an abnormal kidney is still a controversial topic. .... running into fence. AP ... He does not have any prior medical or surgical history.

  17. Incidental emotions influence risk preference and outcome evaluation.

    Science.gov (United States)

    Zhao, Ding; Gu, Ruolei; Tang, Ping; Yang, Qiwei; Luo, Yue-Jia

    2016-10-01

    Incidental emotions, which are irrelevant to the current decision, play a significant role in the decision-making process. In this study, to investigate the influence of incidental emotions on behavioral, psychological, and electrophysiological responses in the process of decision making, participants were required to perform a monetary gambling task. During the selection stage, an emotional picture, which was chosen from the Chinese Affective Picture System and fell into one of three categories: negative, neutral, and positive, was presented between two alternatives (small/large amount of bet). The pictures were provided to induce incidental emotions. ERPs and self-rating emotional experiences to outcome feedback were recorded during the task. Behavioral results showed that positive incidental emotions elicited risk preference, but emotional experiences to outcome feedback were not influenced by incidental emotions. The feedback-related negativity amplitudes were larger in the positive emotion condition than in the negative and neutral emotion conditions for small outcomes (including wins and losses), whereas there was no difference between the three conditions for large outcomes. In addition, the amplitudes of P3 were reduced overall in the negative emotion condition. We suggest that incidental emotions have modulated both the option assessment stage (manifested in behavioral choices) and the outcome evaluation stage (manifested in ERP amplitudes) of decision making unconsciously (indicated by unchanged subjective emotional experiences). The current findings have expanded our understanding of the role of incidental emotion in decision making. © 2016 Society for Psychophysiological Research.

  18. LCA Experiences in Danish Industry: Results of a Survey

    DEFF Research Database (Denmark)

    Broberg, Ole; Christensen, Per

    1999-01-01

    A study on Danish industry's experiences with LCA has been performed. Twenty-six enterprises from different sectors filled in a questionnaire. The enterprises are still in an adoption and learning phase and experiences with full-blown LCA's are sparse. Expectations of future market pressure...

  19. Are functional fillers improving environmental behavior of plastics? A review on LCA studies.

    Science.gov (United States)

    Civancik-Uslu, Didem; Ferrer, Laura; Puig, Rita; Fullana-I-Palmer, Pere

    2018-06-01

    The use of functional fillers can be advantageous in terms of cost reduction and improved properties in plastics. There are many types of fillers used in industry, organic and inorganic, with a wide application area. As a response to the growing concerns about environmental damage that plastics cause, recently fillers have started to be considered as a way to reduce it by decreasing the need for petrochemical resources. Life cycle assessment (LCA) is identified as a proper tool to evaluate potential environmental impacts of products or systems. Therefore, in this study, the literature regarding LCA of plastics with functional fillers was reviewed in order to see if the use of fillers in plastics could be environmentally helpful. It was interesting to find out that environmental impacts of functional fillers in plastics had not been studied too often, especially in the case of inorganic fillers. Therefore, a gap in the literature was identified for the future works. Results of the study showed that, although there were not many and some differences exist among the LCA studies, the use of fillers in plastics industry may help to reduce environmental emissions. In addition, how LCA methodology was applied to these materials was also investigated. Copyright © 2018 Elsevier B.V. All rights reserved.

  20. A thematic review of life cycle assessment (LCA) applied to pig production

    International Nuclear Information System (INIS)

    McAuliffe, Graham A.; Chapman, Deborah V.; Sage, Colin L.

    2016-01-01

    Commercial livestock production is known to have significant impacts on the environment. Pig production is a complex system which involves the production of animal feed, transportation, animal rearing and waste management. One tool for assessing the environmental performance of such complex systems is life cycle assessment (LCA). LCA has been applied to pig production considerably to date. This paper provides a chronological review of state-of-the-art pig production LCAs under three themes: feed production; entire-system livestock rearing; and waste management. The study considers how LCA applications have addressed technological improvements in animal husbandry, and highlights methodological limitations, particularly related to cross-study comparisons. Recent research demonstrates crude protein reduction in feed and anaerobic treatment of pig excreta resulting in bioenergy production are the key targets for environmental performance improvements related to pig production. - Highlights: • An extensive review of LCA applied to pig production is provided chronologically over the past decade. • Individual studies have been categorised into feed, whole-system pig production and waste management themes. • We consider how LCAs have addressed state-of-the-art pig husbandry. • We offer a discussion on key findings, limitations and future research.

  1. A thematic review of life cycle assessment (LCA) applied to pig production

    Energy Technology Data Exchange (ETDEWEB)

    McAuliffe, Graham A., E-mail: g.a.mcauliffe@umail.ucc.ie [Department of Geography, University College Cork, O' Donovan' s Road, Cork (Ireland); School of Biological, Earth and Environmental Sciences, University College Cork, Distillery Fields, North Mall, Cork (Ireland); Chapman, Deborah V. [School of Biological, Earth and Environmental Sciences, University College Cork, Distillery Fields, North Mall, Cork (Ireland); Sage, Colin L. [Department of Geography, University College Cork, O' Donovan' s Road, Cork (Ireland)

    2016-01-15

    Commercial livestock production is known to have significant impacts on the environment. Pig production is a complex system which involves the production of animal feed, transportation, animal rearing and waste management. One tool for assessing the environmental performance of such complex systems is life cycle assessment (LCA). LCA has been applied to pig production considerably to date. This paper provides a chronological review of state-of-the-art pig production LCAs under three themes: feed production; entire-system livestock rearing; and waste management. The study considers how LCA applications have addressed technological improvements in animal husbandry, and highlights methodological limitations, particularly related to cross-study comparisons. Recent research demonstrates crude protein reduction in feed and anaerobic treatment of pig excreta resulting in bioenergy production are the key targets for environmental performance improvements related to pig production. - Highlights: • An extensive review of LCA applied to pig production is provided chronologically over the past decade. • Individual studies have been categorised into feed, whole-system pig production and waste management themes. • We consider how LCAs have addressed state-of-the-art pig husbandry. • We offer a discussion on key findings, limitations and future research.

  2. Dynamic life cycle assessment (LCA) of renewable energy technologies

    Energy Technology Data Exchange (ETDEWEB)

    Pehnt, M. [Institut for Energy and Environmental Research, Heidelberg (Germany)

    2006-01-01

    Before new technologies enter the market, their environmental superiority over competing options must be asserted based on a life cycle approach. However, when applying the prevailing status-quo Life Cycle Assessment (LCA) approach to future renewable energy systems, one does not distinguish between impacts which are 'imported' into the system due to the 'background system' (e.g. due to supply of materials or final energy for the production of the energy system), and what is the improvement potential of these technologies compared to competitors (e.g. due to process and system innovations or diffusion effects). This paper investigates a dynamic approach towards the LCA of renewable energy technologies and proves that for all renewable energy chains, the inputs of finite energy resources and emissions of greenhouse gases are extremely low compared with the conventional system. With regard to the other environmental impacts the findings do not reveal any clear verdict for or against renewable energies. Future development will enable a further reduction of environmental impacts of renewable energy systems. Different factors are responsible for this development, such as progress with respect to technical parameters of energy converters, in particular, improved efficiency; emissions characteristics; increased lifetime, etc.; advances with regard to the production process of energy converters and fuels; and advances with regard to 'external' services originating from conventional energy and transport systems, for instance, improved electricity or process heat supply for system production and ecologically optimized transport systems for fuel transportation. The application of renewable energy sources might modify not only the background system, but also further downstream aspects, such as consumer behavior. This effect is, however, strongly context and technology dependent. (author)

  3. Intentional Learning Vs Incidental Learning

    OpenAIRE

    Shahbaz Ahmed

    2017-01-01

    This study is conducted to demonstrate the knowledge of intentional learning and incidental learning. Hypothesis of this experiment is intentional learning is better than incidental learning, participants were demonstrated and were asked to learn the 10 non sense syllables in a specific sequence from the colored cards in the end they were asked to recall the background color of each card instead of non-sense syllables. Independent variables of the experiment are the colored cards containing n...

  4. Incorporating Health Impacts from Exposure to Chemicals in Food Packaging in LCA

    DEFF Research Database (Denmark)

    Ernstoff, Alexi; Trier, Xenia; Jolliet, Oliver

    2014-01-01

    Life cycle assessments (LCA) on the environmental and public health impacts of food and beverage packaging materials have found some advantages to plastic over glass. Entirely missing from these evaluations are the health impacts of possible chemical, e.g. endocrine dis-ruptor, exposure through...... migration of chemicals from the packaging into the food product. We build a framework based on a life cycle perspective to predict which chemicals may be in a package that are not intentionally added ingredients, and we apply this approach to the US EPA’s CPCAT database. In total we find 1,154 chemicals...... within the CPCAT database related to food-contact materials; out of these 107 are potential endocrine disruptors according to the TEDX list of endocrine disruptors. We also build a framework in an effort to begin harmonizing LCA to include health impacts of chemical exposure related to food packaging...

  5. poLCA: An R Package for Polytomous Variable Latent Class Analysis

    Directory of Open Access Journals (Sweden)

    Drew A. Linzer

    2011-08-01

    Full Text Available poLCA is a software package for the estimation of latent class and latent class regression models for polytomous outcome variables, implemented in the R statistical computing environment. Both models can be called using a single simple command line. The basic latent class model is a finite mixture model in which the component distributions are assumed to be multi-way cross-classification tables with all variables mutually independent. The latent class regression model further enables the researcher to estimate the effects of covariates on predicting latent class membership. poLCA uses expectation-maximization and Newton-Raphson algorithms to find maximum likelihood estimates of the model parameters.

  6. Private Arbitration of Incidental Public Law Issues

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2009-01-01

     The article discusses the incidental public law issues which can arise in an arbitration case, e.g. concerning power, heating, natural gas and other public facility legislation, national or Community legal restrictive trade practices law, and rules on state administration approval of the terms...... by arbitration, and where the award is nullifiable only if its findings are in violation of public policy, the ordre public. The article relies on UNCITRAL's Model Arbitration Law, the new Danish arbitration act (DAA), national European case law, and literature and case law of the European Court....

  7. Understanding the LCA and ISO water footprint: A response to ...

    Science.gov (United States)

    Water footprinting has emerged as an important approach to assess water use related effects from consumption of goods and services. Assessment methods are proposed by two different communities, the Water Footprint Network (WFN) and the Life Cycle Assessment (LCA) community. The proposed methods are broadly similar and encompass both the computation of water use and its impacts, but differ in communication of a water footprint result. In this paper, we explain the role and goal of LCA and ISO-compatible water footprinting and resolve the six issues raised by Hoekstra (2016) in “A critique on the water-scarcity weighted water footprint in LCA”. By clarifying the concerns, we identify both the overlapping goals in the WFN and LCA water footprint assessments and discrepancies between them. The main differing perspective between the WFN and LCA-based approach seems to relate to the fact that LCA aims to account for environmental impacts, while the WFN aims to account for water productivity of global fresh water as a limited resource. We conclude that there is potential to use synergies in research for the two approaches and highlight the need for proper declaration of the methods applied. This paper advances efforts to understand ways to accurately capture use of water in life cycle analysis in other contexts. As the paper indicates, there is a discussion about whether quantities of water should be weighted by some local stress factor. This paper attempts to brid

  8. LCA sensitivity analysis of a multi-megawatt wind turbine

    International Nuclear Information System (INIS)

    Martinez, E.; Jimenez, E.; Blanco, J.; Sanz, F.

    2010-01-01

    During recent years renewables have been acquiring gradually a significant importance in the world market (especially in the Spanish energetic market) and in society; this fact makes clear the need to increase and improve knowledge of these power sources. Starting from the results of a Life Cycle Assessment (LCA) of a multi-megawatt wind turbine, this work is aimed to assess the relevance of different choices that have been made during its development. Looking always to cover the largest possible spectrum of options, four scenarios have been analysed, focused on four main phases of lifecycle: maintenance, manufacturing, dismantling, and recycling. These scenarios facilitate to assess the degree of uncertainty of the developed LCA due to choices made, excluding from the assessment the uncertainty due to the inaccuracy and the simplification of the environmental models used or spatial and temporal variability in different parameters. The work has been developed at all times using the of Eco-indicator99 LCA method. (author)

  9. LCA sensitivity analysis of a multi-megawatt wind turbine

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, E. [Grupo Eolicas Riojanas, Carretera de Laguardia, 91-93, 26006 Logrono, La Rioja (Spain); Department of Mechanical Engineering, University of La Rioja, Logrono, La Rioja (Spain); Jimenez, E. [Department of Electrical Engineering, University of La Rioja, Logrono, La Rioja (Spain); Blanco, J.; Sanz, F. [Department of Mechanical Engineering, University of La Rioja, Logrono, La Rioja (Spain)

    2010-07-15

    During recent years renewables have been acquiring gradually a significant importance in the world market (especially in the Spanish energetic market) and in society; this fact makes clear the need to increase and improve knowledge of these power sources. Starting from the results of a Life Cycle Assessment (LCA) of a multi-megawatt wind turbine, this work is aimed to assess the relevance of different choices that have been made during its development. Looking always to cover the largest possible spectrum of options, four scenarios have been analysed, focused on four main phases of lifecycle: maintenance, manufacturing, dismantling, and recycling. These scenarios facilitate to assess the degree of uncertainty of the developed LCA due to choices made, excluding from the assessment the uncertainty due to the inaccuracy and the simplification of the environmental models used or spatial and temporal variability in different parameters. The work has been developed at all times using the of Eco-indicator99 LCA method. (author)

  10. Addressing crop interactions within cropping systems in LCA

    DEFF Research Database (Denmark)

    Goglio, Pietro; Brankatschk, Gerhard; Knudsen, Marie Trydeman

    2018-01-01

    objectives of this discussion article are as follows: (i) to discuss the characteristics of cropping systems which might affect the LCA methodology, (ii) to discuss the advantages and the disadvantages of the current available methods for the life-cycle assessment of cropping systems, and (iii) to offer...... management and emissions, and (3) functional unit issues. The LCA approaches presented are as follows: cropping system, allocation approaches, crop-by-crop approach, and combined approaches. The various approaches are described together with their advantages and disadvantages, applicability...... considers cropping system issues if they are related to multiproduct and nutrient cycling, while the crop-by-crop approach is highly affected by assumptions and considers cropping system issues only if they are related to the analyzed crop. Conclusions Each LCA approach presents advantages and disadvantages...

  11. LIFE CYCLE ASSESSMENT (LCA AS A TOOL FOR BUSINESS STRATEGY

    Directory of Open Access Journals (Sweden)

    Rodrigo Salvador

    2014-09-01

    Full Text Available The growing concern about the development of sustainable production systems leads organizations to seek the support of management tools for decision-making. Considering the whole life cycle of the product, the Life Cycle Assessment (LCA has an important role in this scenario. The objective of this paper is to present, through the theoretical discussion, the role of LCA in strategic planning of the organization. It showed the enormous potential for decision making on the environmental aspect, but also the critical factor in the development shares in the competitive context. The use of LCA can reduce the environmental impacts of the system under study (primary purpose and guide the range of advantages in the fields of marketing, legislation and environmental labeling, competitive strategies, efficiency use of resources and others.

  12. Cradle to Cradle and LCA – is there a conflict?

    DEFF Research Database (Denmark)

    Bjørn, Anders; Hauschild, Michael Zwicky

    2011-01-01

    The Cradle to Cradle (C2C) approach to ecodesign has been gaining increasing interest among industries, authorities and consumers over the last years. With its focus on resource conservation through closing loops, use of solar-based energy sources, avoidance of certain chemicals and the stated aim...... to create good rather than just avoid doing too much evil, it appeals more to industry than traditional LCA-based ecodesign. What are the real differences between the two approaches, and is there a conflict? Potential points of divergence between C2C and LCA are identified and the ability of C2C to support...

  13. An improved model for estimating pesticide emissions for agricultural LCA

    DEFF Research Database (Denmark)

    Dijkman, Teunis Johannes; Birkved, Morten; Hauschild, Michael Zwicky

    2011-01-01

    Credible quantification of chemical emissions in the inventory phase of Life Cycle Assessment (LCA) is crucial since chemicals are the dominating cause of the human and ecotoxicity-related environmental impacts in Life Cycle Impact Assessment (LCIA). When applying LCA for assessment of agricultural...... products, off-target pesticide emissions need to be quantified as accurately as possible because of the considerable toxicity effects associated with chemicals designed to have a high impact on biological organisms like for example insects or weed plants. PestLCI was developed to estimate the fractions...

  14. Kajian Dampak Lingkungan Global dari Kegiatan Keramba Jaring Apung melalui Life Cycle Assessment (LCA

    Directory of Open Access Journals (Sweden)

    Tri Heru Prihadi

    2016-11-01

    and other aquatic organisms, and further, may cause fish mass mortality. Recently these conditions have not fully solved by Indonesian scientists. Application of Best Management Practice (BMP with Life Cycle Assessment (LCA using quantitative model is the best way for implementing a Sustainable Aquaculture. This case was the first attempt of using the quantitative LCA in Indonesia. This research was conducted to quantify and evaluate environmental aspects that were affected by floating net cage (KJA. The result showed that fish culture in KJA contributed significant impacts to the aquatic environment. From many factors of KJA, feed was the most dominant factor that caused the global environmental impact (above 70%, in form of global warming potential, abiotic depletion, eutrophycation, ozone depletion potential, human toxicity, and biodiversity depletion. Feed consist of many substances. Soybean Brazil and winter wheat were the major substances that brought out the most environmental impact. Thus, it is important to find alternative materials to substitute these substances. Other factors of KJA (plastic drums, polystyrene foam, bamboo, steel, net, farming scale, etc. also affected the quantity and kind of impacts to aquatic environment.

  15. Introduction to Part III: Application of LCA in Practice

    DEFF Research Database (Denmark)

    Rosenbaum, Ralph K.

    2018-01-01

    While Part II of this book presents the theoretical foundation and methodology of LCA, Part III is dedicated to a comprehensive discussion of how this methodology has been adapted and applied in practice. The chapters of Part III provide an easily readable and accessible introduction to different...

  16. LCA single score analysis of man-made cellulose fibres

    NARCIS (Netherlands)

    Shen, L.; Patel, M.K.

    2010-01-01

    In this study, the LCA report “Life Cycle assessment of man-made cellulose fibres” [3] is extended to the single score analysis in order to provide an additional basis for decision making. The single score analysis covers 9 to 11 environmental impact categories. Three single score methods (Single

  17. Radiology reports for incidental thyroid nodules on CT and MRI: high variability across subspecialties.

    Science.gov (United States)

    Grady, A T; Sosa, J A; Tanpitukpongse, T P; Choudhury, K R; Gupta, R T; Hoang, J K

    2015-02-01

    Variability in radiologists' reporting styles and recommendations for incidental thyroid nodules can lead to confusion among clinicians and may contribute to inconsistent patient care. Our aim was to describe reporting practices of radiologists for incidental thyroid nodules seen on CT and MR imaging and to determine factors that influence reporting styles. This is a retrospective study of patients with incidental thyroid nodules reported on CT and MR imaging between January and December 2011, identified by text search for "thyroid nodule" in all CT and MR imaging reports. The studies included CT and MR imaging scans of the neck, spine, and chest. Radiology reports were divided into those that mentioned the incidental thyroid nodules only in the "Findings" section versus those that reported the incidental thyroid nodules in the "Impression" section as well, because this latter reporting style gives more emphasis to the finding. Univariate and multivariate analyses were performed to identify radiologist, patient, and nodule characteristics that influenced reporting styles. Three hundred seventy-five patients met the criterion of having incidental thyroid nodules. One hundred thirty-eight (37%) patients had incidental thyroid nodules reported in the "Impression" section. On multivariate analysis, only radiologists' divisions and nodule size were associated with reporting in "Impression." Chest radiologists and neuroradiologists were more likely to report incidental thyroid nodules in the "Impression" section than their abdominal imaging colleagues, and larger incidental thyroid nodules were more likely to be reported in "Impression" (P ≤ .03). Seventy-three percent of patients with incidental thyroid nodules of ≥20 mm were reported in the "Impression" section, but higher variability in reporting was seen for incidental thyroid nodules measuring 10-14 mm and 15-19 mm, which were reported in "Impression" for 61% and 50% of patients, respectively. Reporting

  18. INCIDENTAL VOCABULARY LEARNING THROUGH READING

    Directory of Open Access Journals (Sweden)

    Holly Warzecha, M.A. TESOL

    2017-04-01

    Full Text Available The purpose of the following paper is to take a closer look at the benefits of incidental learning through reading, with a specific focus on vocabulary acquisition. The teaching of vocabulary has traditionally been an explicit process where the target vocabulary is taken out of context and taught separately. However, this kind of explicit teaching and learning may only take into account a form-meaning connection. Therefore, this paper explores research on incidental learning and specifically looks at what it takes to acquire new vocabulary incidentally through reading while considering the coverage rates of texts, how many words must be known already from the text, how many repetitions it takes to learn a word, types of texts that promote learning, and the effects of pairing students‘ reading with learner tasks. After reviewing many studies, it can be concluded that more reading is better. More specifically, extensive reading of chosen novels at an appropriate level and interest to the students showed important gains in vocabulary. In addition, readings that were supplemented with additional activities that focused on both form and meaning showed an even higher increase in word retention.

  19. Using Incidental Vocabulary Acquisition to Enrich the Students Vocabulary Mastery

    OpenAIRE

    Asmayanti, St

    2015-01-01

    The research aimed to find out the improvement the students'vocabulary in terms of improving their understanding about of nouns and adjectives. To explain the increase, the researcher used a classroom action research (CAR) which was conducted in two cycles in which each cycle consisted of four meetings.The subject was the students at the eight grade of SMP Askari Pallangga Gowa. The number of samples consisted of 37 students. The research findings indicated that using Incidental Vocabulary Ac...

  20. 78 FR 33357 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

    Science.gov (United States)

    2013-06-04

    ... confidence in these values is unknown. Table 3--Marine Mammal Density Estimates Density Species (animals/km\\2... unintentional taking of marine animals occurring incidental to the shock testing which involved large explosives... Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to Conducting...

  1. Management of an incidentally discovered pulmonary nodule

    International Nuclear Information System (INIS)

    Beigelman-Aubry, Catherine; Hill, Catherine; Grenier, Philippe A.

    2007-01-01

    The incidental finding of a pulmonary nodule on computed tomography (CT) is becoming an increasingly frequent event. The discovery of such a nodule should evoke the possibility of a small bronchogenic carcinoma, for which excision is indicated without delay. However, invasive diagnostic procedures should be avoided in the case of a benign lesion. The objectives of this review article are: (1) to analyze the CT criteria defining benign nodules, nodules of high suspicion of malignancy and indeterminate nodules, (2) to analyze the diagnostic performances and limitations of complementary investigations requested to characterize indeterminate lung nodules, (3) to review the criteria permitting to assess the probability of malignancy of indeterminate nodules and (4) to report on the new guidelines provided by the Fleischner Society for the management of small indeterminate pulmonary nodules, according to their prior probability of malignancy. (orig.)

  2. Making the most of LCA in technical inter-organisational R&D projects

    DEFF Research Database (Denmark)

    Sandin, Gustav; Clancy, Gunilla; Heimersson, Sara

    2014-01-01

    In technical Research and Development (R&D) projects, a Life Cycle Assessment (LCA) of the technology under development is sometimes carried out. Particularly in inter-organisational R&D projects, the roles of LCAs tend to be unclear and arbitrary, and as a consequence, LCA work is not adequately...... designed for the needs of the project. There is a need for research on how to choose an appropriate role for LCA in such projects and how to plan LCA work accordingly. We have identified some possible roles of LCA in inter-organisational R&D projects and used experiences from LCA work in different...... such projects to identify four project characteristics that are decisive for what roles the LCA can have. The project characteristics are: (i) the project's potential influence on environmental impacts, (ii) the degrees of freedom available for the technical direction of the project, (iii) the project...

  3. Application of Life Cycle Assessment (LCA) in Sugar Industries

    Science.gov (United States)

    Astuti, Arieyanti Dwi; Astuti, Rahayu Siwi Dwi; Hadiyanto, Hadiyanto

    2018-02-01

    Sugar is one of the main commodities that are needed for human life. The demand of sugar is very high with the trend increase from year to year. This condition makes the sugar industry become a leading industry that must be maintained sustainability. The sustainability of the sugar industry is influenced by the use of energy and natural resources and the resulting environmental impacts. Therefore, an effort is needed to analyze the environmental aspects and potential environmental impacts resulting from a product (sugar), by using Life Cycle Assessment (LCA). LCA is a very important tool for the analysis of a process/system from its cradle to grave. This technique is very useful in the estimation of energy usage and environmental load of a product/system. This paper aims to describe the main elements of sugar industries using Life Cycle Assessment.

  4. Integrating LCA and EHS expertise in the assessment of nanoparticles

    DEFF Research Database (Denmark)

    Olsen, Stig Irving; Hankin, Steve; Chaudry, Qasim

    DTU with their expertise in LCA have joined forces with IOM in two nanotechnology-related projects, one of which additionally involves and is lead by FERA. The first project, Nancore, includes the evaluation of health risks and environmental impacts over the life cycle concurrently with the devel......DTU with their expertise in LCA have joined forces with IOM in two nanotechnology-related projects, one of which additionally involves and is lead by FERA. The first project, Nancore, includes the evaluation of health risks and environmental impacts over the life cycle concurrently...... the overall environmental impacts of the technology. Through the concurrent assessments, the strengths of the two tools are combined to provide a more qualified assessment of both the health and safety aspects and the life cycle impacts. The overall aim of the second project, sponsored by Defra...

  5. Challenges in LCA modelling of multiple loops for aluminium cans

    DEFF Research Database (Denmark)

    Niero, Monia; Olsen, Stig Irving

    considered the case of closed-loop recycling for aluminium cans, where body and lid are different alloys, and discussed the abovementioned challenge. The Life Cycle Inventory (LCI) modelling of aluminium processes is traditionally based on a pure aluminium flow, therefore neglecting the presence of alloying...... elements. We included the effect of alloying elements on the LCA modelling of aluminium can recycling. First, we performed a mass balance of the main alloying elements (Mn, Fe, Si, Cu) in aluminium can recycling at increasing levels of recycling rate. The analysis distinguished between different aluminium...... packaging scrap sources (i.e. used beverage can and mixed aluminium packaging) to understand the limiting factors for multiple loop aluminium can recycling. Secondly, we performed a comparative LCA of aluminium can production and recycling in multiple loops considering the two aluminium packaging scrap...

  6. 2d-LCA - an alternative to x-wires

    Science.gov (United States)

    Puczylowski, Jaroslaw; Hölling, Michael; Peinke, Joachim

    2014-11-01

    The 2d-Laser Cantilever Anemometer (2d-LCA) is an innovative sensor for two-dimensional velocity measurements in fluids. It uses a micostructured cantilever made of silicon and SU-8 as a sensing element and is capable of performing mesurements with extremly high temporal resolutions up to 150 kHz. The size of the cantilever defines its spatial resolution, which is in the order of 150 μm only. Another big feature is a large angular range of 180° in total. The 2d-LCA has been developed as an alternative measurement method to x-wires with the motivation to create a sensor that can operate in areas where the use of hot-wire anemometry is difficult. These areas include measurements in liquids and in near-wall or particle-laden flows. Unlike hot-wires, the resolution power of the 2d-LCA does not decrease with increasing flow velocity, making it particularly suitable for measurements in high speed flows. Comparative measurements with the 2d-LCA and hot-wires have been carried out in order to assess the performance of the new anemometer. The data of both measurement techniques were analyzed using the same stochastic methods including a spectral analysis as well as an inspection of increment statistics and structure functions. Furthermore, key parameters, such as mean values of both velocity components, angles of attack and the characteristic length scales were determined from both data sets. The analysis reveals a great agreement between both anemometers and thus confirms the new approach.

  7. LCA as a Tool to Evaluate Green Infrastructure's Environmental Performance

    Science.gov (United States)

    Catalano De Sousa, M.; Erispaha, A.; Spatari, S.; Montalto, F.

    2011-12-01

    Decentralized approaches to managing urban stormwater through use of green infrastructure (GI) often lead to system-wide efficiency gains within the urban watershed's energy supply system. These efficiencies lead to direct greenhouse gas (GHG) emissions savings, and also restore some ecosystem functions within the urban landscape. We developed a consequential life cycle assessment (LCA) model to estimate the life cycle energy, global warming potential (GWP), and payback times for each if GI were applied within a select neighborhood in New York City. We applied the SIMAPRO LCA software and the economic input-output LCA (EIO-LCA) tool developed by Carnegie Mellon University. The results showed that for a new intersection installation highlighted in this study a conventional infrastructure construction would emit and use approximately 3 times more for both CO2 and energy than a design using GI. Two GI benefits were analyzed with regards to retrofitting the existing intersection. The first was related to the savings in energy and CO2 at the Waste Water Treatment Plant via runoff reduction accrued from GI use. The second benefit was related to the avoided environmental costs associated with an additional new grey infrastructure installation needed to prevent CSO in case of no GI implementation. The first benefit indicated a high payback time for a GI installation in terms of CO2 and energy demand (80 and 90 years respectively) and suggest a slow energy and carbon recovery time. However, concerning to the second benefit, GI proved to be a sustainable alternative considering the high CO2 releases (429 MTE) and energy demand (5.5 TJ) associated with a grey infrastructure construction.

  8. Potential and limitations of environmental design with LCA tools

    Directory of Open Access Journals (Sweden)

    Alexander Hollberg

    2017-10-01

    Full Text Available The built environment has a very high impact on the environment. Architects can largely define the environmental impact a building will cause throughout its lifetime through its design. Especially the choice of material and the type of construction can be influenced in early design stages. To quantify the environmental impact, tools for Life Cycle Assessment (LCA are used. This paper discusses the results of four case studies of applying four different novel LCA tools in four different academic courses at different universities. The results show that the success of applying LCA tools highly depends on the point of time during the design process and the design strategy the student pursues. If the right tool is used at the right moment and matches the design strategy, it can help to improve the architectural quality and reduce environmental impacts. In most cases however, the time of application did not fit, resulting in additional effort for applying the LCA tool. In consequence, the architectural elaboration of the design and the improvement of environmental performance compete against each other. Either the architectural quality suffers or the tool is employed late and the environmental performance cannot be improved. Even if the point in time of the tool application is right, the success depends highly on the design strategy. The number of tools is growing and there is an adequate tool available for each design stage. The design strategy has to match the tool and this requires a willingness to adapt the design approach. The issue of environmental design shifted from a lack of adequate tools to the lack of adequate design approaches. Tools can be easily taught in seminars. Environmental design strategies, however, have to be included in design studios and developed throughout the entire design phase to become part of architectural education.

  9. WILCI: a LCA tool dedicated to MSW incineration in France

    OpenAIRE

    Beylot , Antoine; Muller , Stéphanie; Descat , Marie; Ménard , Yannick; Michel , Pascale; Villeneuve , Jacques

    2017-01-01

    International audience; Life Cycle Assessment (LCA) has been increasingly used in the last decades to evaluate the global environmental performance of waste treatment options. This is in particular the case considering incineration that is the major treatment route for Municipal Solid Waste (MSW) in France (28% of French MSW are incinerated, in 126 MSW incineration plants; ADEME, 2015). In this context, this article describes a new Excel-tool, WILCI (for Waste Incineration Life Cycle Inventor...

  10. Life cycle assessment of products and technologies. LCA Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Koukkari, H.; Nors, M. (eds.)

    2009-12-15

    VTT Technical Research Centre of Finland organised a Symposium 'Life Cycle Assessment of Products and Technologies' on the 6th of October, 2009. The Symposium gave a good overview of methods, tools and applications of Life Cycle Assessment developed and utilised in several technology fields of VTT. The 12 Symposium papers deal with recent LCA studies on products and technologies. The scope ranges from beverage cups to urban planning, from inventory databases to rating systems. Topical issues relating to climate change concern biorefineries and the overall impacts of the utilisation of biomass. The calculation of carbon footprints is also introduced through paper products and magazines. One example of LCA tools developed at VTT addresses cement manufacturing. VTT's transport emission database, LIPASTO, was introduced in detail. The use of LCA methods and life cycle thinking is described in various contexts: product development in relation to precision instruments; selection of materials and work processes in relation to sediment remediation project; and procedures of sustainability rating through VTT's office building Digitalo. The Climate Bonus project presented a demonstrated ICT support that informs about the greenhouse gas emissions and carbon footprints of households. (orig.)

  11. Animation, Incidental Learning, and Continuing Motivation.

    Science.gov (United States)

    Rieber, Lloyd P.

    1991-01-01

    Effects of animated graphics presentations on incidental learning and the degree to which various computer practice activities contain intrinsically motivating characteristics were studied with 70 fourth graders learning about Newton's laws of motion. Incidental learning occurred without sacrifice of intentional learning. Students were highly…

  12. Prevalence and associated factors of incidentally diagnosed ...

    African Journals Online (AJOL)

    ... prostate specific antigen and Biopsy results were analyzed using STATA 11. The prevalence of incidental prostatic cancer was calculated and logistic regression ... had PSA >10 ng/mL and in total; 33 (21.71%) had incidental prostatic carcinoma. ... prostatectomy for presumed benign prostatic hyperplasia in Tanzania with ...

  13. 47 CFR 15.13 - Incidental radiators.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Incidental radiators. 15.13 Section 15.13 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES General § 15.13 Incidental radiators. Manufacturers of these devices shall employ good engineering practices to minimize the risk of...

  14. Innovation strategies in a fruit growers association impacts assessment by using combined LCA and s-LCA methodologies.

    Science.gov (United States)

    Tecco, Nadia; Baudino, Claudio; Girgenti, Vincenzo; Peano, Cristiana

    2016-10-15

    In the challenging world of territorial transformations within the agriculture, there is an increasing need for an integrated methodological framework of assessment that is able to reconcile the demand for solutions that are both economically sustainable and contribute to environmental and social improvement. This study aims to assess the introduction of innovation into agro-food systems by combining an environmental life cycle (LCA) assessment and a social life cycle assessment (s-LCA) to support the decision making process of a fruit growers co-op for the adoption of mulching and covering in raspberry farming. LCA and s-LCA have been applied independently under specific consistency requirements, selecting two scenarios to compare the impact with (1) and without (2) the innovation and then combined within a cause-effect chain. The interactions between the environment and socioeconomic components were considered within a nested frameset of business and territorial features. The total emissions from raspberry production in Scenario 1, according to the Global Warming Potential (GWP) Impact Category amounted to 2.2840kg of CO2 eq. In Scenario 2, the impact of production was associated with a GWP of 0.1682kg of CO2 eq. Social repercussions analysis from Scenario 1 compared to Scenario 2 indicate more satisfaction for working conditions and the management of climate risks. The mulching and covering, implemented within a given framework of farm activity, created conditions for the preservation of a model in which raspberry production contributes to landscape protection, the business sustainability of farms and the creation of employment. The combined use of the two methods contributes to the development of a strategy planning due to its ability to deliver, as well as specific analysis at a functional level, a wider framework for assessing the consistency of the impacts related to innovation in raspberry production. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Incidentals

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The Master-of-Nets Garden has characteristic night scenery. From March 15 to November 20, it is open to visitors in the evenings. Apart from viewing the garden by night, visitors can also enjoy performances full of local color, such as pingtan (story telling and ballad singing in Suzhou dialect), music played on the guzheng (zither-like musical instruments), and Kunqu Opera.

  16. Incidental Learning of Melodic Structure of North Indian Music.

    Science.gov (United States)

    Rohrmeier, Martin; Widdess, Richard

    2017-07-01

    Musical knowledge is largely implicit. It is acquired without awareness of its complex rules, through interaction with a large number of samples during musical enculturation. Whereas several studies explored implicit learning of mostly abstract and less ecologically valid features of Western music, very little work has been done with respect to ecologically valid stimuli as well as non-Western music. The present study investigated implicit learning of modal melodic features in North Indian classical music in a realistic and ecologically valid way. It employed a cross-grammar design, using melodic materials from two modes (rāgas) that use the same scale. Findings indicated that Western participants unfamiliar with Indian music incidentally learned to identify distinctive features of each mode. Confidence ratings suggest that participants' performance was consistently correlated with confidence, indicating that they became aware of whether they were right in their responses; that is, they possessed explicit judgment knowledge. Altogether our findings show incidental learning in a realistic ecologically valid context during only a very short exposure, they provide evidence that incidental learning constitutes a powerful mechanism that plays a fundamental role in musical acquisition. Copyright © 2016 Cognitive Science Society, Inc.

  17. Beginning LCA. A guide into environmental life cycle assessment

    Energy Technology Data Exchange (ETDEWEB)

    Van den Berg, N.W. [ed.; Huppes, G. [Centre of Environmental Science CLM, Leiden University, Leiden (Netherlands); Dutilh, C.E. [Unilever, Van den Bergh Netherlands, Rotterdam (Netherlands)

    1995-02-01

    The main goal of this document is to provide practical guidance for those who want to start with Life Cycle Assessment (LCA). The document has been set up in the form of modules. Module 1 provides arguments to decide whether or not LCA is the right tool to use in a particular case. In this module other ways to study interactions with the environment will be mentioned as well. Module 2 explains the process of formulating the purpose and scope of the study. The results will give a general picture of the characteristics of the LCA. The next step, which is called the inventory analysis, represents the largest amount of work and is split up into four parts, i.e. Modules 3,4,5, and 6. Module 3 gives guidelines and detailed examples on how to construct a flowchart of the study. Module 5 describes how to collect the required data and Module 4 how to define the system boundaries. Finally, the processing of data is described in Module 6. The result of the inventory is a list of emissions and extractions for all processes involved in manufacturing and required for the functioning of a product, service or activity during the entire life cycle. Sometimes results are so clear that you may decide to stop after the inventory stage. Usually however, it is useful to carry out the impact assessment, which is split up into two parts (Modules 7 and 8). Instructions are given on how to translate the list of environmental interventions of the entire life cycle of the product into a table with scores on environmental themes: the classification/characterization. A basic substance list that might be used is added (Module 7). Also a description showing how to evaluate the results of the classification/characterization is given, so that conclusions may be drawn on the information that has been generated (Module 8). Module 9, the last module, describes how to complete the LCA. It provides suggestions on how to present the results and indications about the improvement analysis.

  18. REVIEW OF EXISTING LCA STUDIES ON WASTE WATER TREATMENT TECHNOLOGIES

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred; Hauschild, Michael Zwicky

    The EU research project “NEPTUNE” is related to the EU Water Framework Directive and focused on the development of new waste water treatment technologies (WWTT) for municipal waste water. The sustainability of these WWTTs is going to be assessed by the use of life cycle assessment (LCA). New life...... importance of the different life cycle stages and the individual impact categories in the total impact from the waste water treatment, and the degree to which micropollutants, pathogens and whole effluent toxicity have been included in earlier studies. The results show that more than 30 different WWTT (and...

  19. The importance of the application context for the design of Social LCA methodology

    DEFF Research Database (Denmark)

    Jørgensen, Andreas

    comprises users of the Social LCA, their target audience, ethical considerations of relevance to the application of Social LCA, and legal limitations. The users of the Social LCA are either companies, NGOs or GOs, and the target audience is the recipients of the assessment results from the above mentioned...... user groups. Both users’ and their target audience’s views are found through analysis of interviews with potential user groups. Ethical considerations concern negative social impacts that may occur in relation to the application of Social LCA. These are included here, as it is assumed that the overall...

  20. Incidental mastoid opacification in children on MRI

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Sumit; Kuruva, Manohar [University of Arkansas for Medical Sciences, Pediatric Radiology, Little Rock, AR (United States); Rettiganti, Mallikarjuna Rao [University of Arkansas for Medical Sciences and Arkansas Children' s Hospital Research Institute, Biostatistics Program, Department of Pediatrics, Little Rock, AR (United States); Qin, Curtis [Georgetown University Hospital, Radiology, Washington, DC (United States); Hegde, Shilpa V. [University of Pittsburgh Medical Centre, Section of Neuroradiology, Pittsburgh, PA (United States)

    2016-05-15

    The opacification the mastoid cavity is frequently reported by radiologists on cross-sectional imaging done for non-otological indications. It is well known that presence of fluid the mastoid does not amount to mastoiditis. This study seeks to provide an evidence-based confirmation of this known finding. The purpose of our study was to determine the prevalence of mastoid opacification in children undergoing outpatient brain MRI examination. Our study included 515 outpatient children who had brain MRI for indications other than mastoiditis or otitis media from January 2014 to March 2014. Children with history of skull base trauma or radiation were excluded. The age range was 15 days to 18 years. The overall prevalence of mastoid opacification was determined using one sample proportion and exact 95% Clopper-Pearson confidence intervals. The prevalence of mastoid opacification was analyzed based on gender, age and presenting symptoms using chi-square test of association. One hundred ten children (21.4%) had mastoid opacification. Younger patients tended to have higher opacification rates with the prevalence in children younger than 1 year of age and between 1 and 2 years of age as high as 41.7% (20/48) and 47.5% (38/80), respectively. The diagnosis of mastoiditis in children should not be based upon a radiologist's report of finding fluid or mucosal thickening in the mastoid air cells as incidental opacification the mastoid is seen frequently. (orig.)

  1. Incidental mastoid opacification in children on MRI

    International Nuclear Information System (INIS)

    Singh, Sumit; Kuruva, Manohar; Rettiganti, Mallikarjuna Rao; Qin, Curtis; Hegde, Shilpa V.

    2016-01-01

    The opacification the mastoid cavity is frequently reported by radiologists on cross-sectional imaging done for non-otological indications. It is well known that presence of fluid the mastoid does not amount to mastoiditis. This study seeks to provide an evidence-based confirmation of this known finding. The purpose of our study was to determine the prevalence of mastoid opacification in children undergoing outpatient brain MRI examination. Our study included 515 outpatient children who had brain MRI for indications other than mastoiditis or otitis media from January 2014 to March 2014. Children with history of skull base trauma or radiation were excluded. The age range was 15 days to 18 years. The overall prevalence of mastoid opacification was determined using one sample proportion and exact 95% Clopper-Pearson confidence intervals. The prevalence of mastoid opacification was analyzed based on gender, age and presenting symptoms using chi-square test of association. One hundred ten children (21.4%) had mastoid opacification. Younger patients tended to have higher opacification rates with the prevalence in children younger than 1 year of age and between 1 and 2 years of age as high as 41.7% (20/48) and 47.5% (38/80), respectively. The diagnosis of mastoiditis in children should not be based upon a radiologist's report of finding fluid or mucosal thickening in the mastoid air cells as incidental opacification the mastoid is seen frequently. (orig.)

  2. Relative Preference and Localized Food Affect Predator Space Use and Consumption of Incidental Prey.

    Directory of Open Access Journals (Sweden)

    Tyler E Schartel

    Full Text Available Abundant, localized foods can concentrate predators and their foraging efforts, thus altering both the spatial distribution of predation risk and predator preferences for prey that are encountered incidentally. However, few investigations have quantified the spatial scale over which localized foods affect predator foraging behavior and consumption of incidental prey. In spring 2010, we experimentally tested how point-source foods altered how generalist predators (white-footed mice, Peromyscus leucopus utilized space and depredated two incidental prey items: almonds (Prunus dulcis; highly profitable and maple seeds (Acer saccharum; less profitable. We estimated mouse population densities with trapping webs, quantified mouse consumption rates of these incidental prey items, and measured local mouse activity with track plates. We predicted that 1 mouse activity would be elevated near full feeders, but depressed at intermediate distances from the feeder, 2 consumption of both incidental prey would be high near feeders providing less-preferred food and, 3 consumption of incidental prey would be contingent on predator preference for prey relative to feeders providing more-preferred food. Mouse densities increased significantly from pre- to post-experiment. Mean mouse activity was unexpectedly greatest in control treatments, particularly <15 m from the control (empty feeder. Feeders with highly preferred food (sunflower seeds created localized refuges for incidental prey at intermediate distances (15 to 25m from the feeder. Feeders with less-preferred food (corn generated localized high risk for highly preferred almonds <10 m of the feeder. Our findings highlight the contingent but predictable effects of locally abundant food on risk experienced by incidental prey, which can be positive or negative depending on both spatial proximity and relative preference.

  3. Incidental intraductal papillomas (breast diagnosed on needle core biopsy do not need to be excised.

    Science.gov (United States)

    Jaffer, Shabnam; Bleiweiss, Ira J; Nagi, Chandandeep

    2013-01-01

    Most authors recommend excision of intraductal papillomas diagnosed on core needle biopsy. This leads to the question of whether or not excision is necessary for incidental intraductal papillomas on core needle biopsy as opposed to those corresponding to imaging findings. Using the pathology computerized data base we retrospectively identified 46 incidental intraductal papillomas diagnosed on core needle biopsy from 1/2000 to 12/2008. Clinical, radiologic, and pathologic information was gathered and correlated. All core needle biopsies were reviewed to confirm the diagnosis of incidental intraductal papillomas, and excision specimens reviewed when available. Of the 46 patients, follow-up information was available in only 38. The age of the patients ranged from 39 to 82 years (mean = 48 years). Most incidental intraductal papillomas were diagnosed by mammotome core needle biopsy (36 cases). A total of 33 cases were performed for calcifications with the following indications: clustered = 21, new = 4, pleomorphic = 3, increasing = 3, indeterminant = 2. The correlating diagnoses included the following: fibrocystic changes with calcium phosphate = 18 or calcium oxalate = 10, fibroadenoma with calcifications = 5. The three masses were: two cases of cystic papillary apocrine metaplasia (I Ultrasound and 1 MRI) and 1 fibroadenoma (Ultrasound). In all cases, the intraductal papillomas were ≤0.2 cm, were not associated with calcifications, and were incidental to them or the underlying mass. A total of 14 patients underwent excision, whereas the remaining 24 have remained radiologically stable for over 12 months. The excision specimen findings were: fibrocystic changes = 8 and intraductal papilloma = 6. With the exception of one case, all the intraductal papilloma remained incidental to imaging findings. In this solitary case, the calcifications were described as pleomorphic and corresponded to fibrocystic changes calcifications on core needle

  4. Environmental assessment of digestate treatment technologies using LCA methodology.

    Science.gov (United States)

    Vázquez-Rowe, Ian; Golkowska, Katarzyna; Lebuf, Viooltje; Vaneeckhaute, Céline; Michels, Evi; Meers, Erik; Benetto, Enrico; Koster, Daniel

    2015-09-01

    The production of biogas from energy crops, organic waste and manure has augmented considerably the amounts of digestate available in Flanders. This has pushed authorities to steadily introduce legislative changes to promote its use as a fertilising agent. There is limited arable land in Flanders, which entails that digestate has to compete with animal manure to be spread. This forces many anaerobic digestion plants to further treat digestate in such a way that it can either be exported or the nitrogen be removed. Nevertheless, the environmental impact of these treatment options is still widely unknown, as well as the influence of these impacts on the sustainability of Flemish anaerobic digestion plants in comparison to other regions where spreading of raw digestate is allowed. Despite important economic aspects that must be considered, the use of Life Cycle Assessment (LCA) is suggested in this study to identify the environmental impacts of spreading digestate directly as compared to four different treatment technologies. Results suggest relevant environmental gains when the digestate mix is treated using the examined conversion technologies prior to spreading, although important trade-offs between impact categories were observed and discussed. The promising results of digestate conversion technologies suggest that further LCA analyses should be performed to delve into, for instance, the appropriateness to shift to nutrient recovery technologies rather than digestate conversion treatments. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Experiential Knowledge Complements an LCA-Based Decision Support Framework

    Directory of Open Access Journals (Sweden)

    Heng Yi Teah

    2015-09-01

    Full Text Available A shrimp farmer in Taiwan practices innovation through trial-and-error for better income and a better environment, but such farmer-based innovation sometimes fails because the biological mechanism is unclear. Systematic field experimentation and laboratory research are often too costly, and simulating ground conditions is often too challenging. To solve this dilemma, we propose a decision support framework that explicitly utilizes farmer experiential knowledge through a participatory approach to alternatively estimate prospective change in shrimp farming productivity, and to co-design options for improvement. Data obtained from the farmer enable us to quantitatively analyze the production cost and greenhouse gas (GHG emission with a life cycle assessment (LCA methodology. We used semi-quantitative graphical representations of indifference curves and mixing triangles to compare and show better options for the farmer. Our results empower the farmer to make decisions more systematically and reliably based on the frequency of heterotrophic bacteria application and the revision of feed input. We argue that experiential knowledge may be less accurate due to its dependence on varying levels of farmer experience, but this knowledge is a reasonable alternative for immediate decision-making. More importantly, our developed framework advances the scope of LCA application to support practically important yet scientifically uncertain cases.

  6. PROMOTING INCIDENTAL VOCABULARY LEARNING THROUGH VERBAL DRAMATIZATION OF WORDS

    Directory of Open Access Journals (Sweden)

    Looi-Chin Ch’ng

    2014-12-01

    Full Text Available Despite the fact that explicit teaching of vocabulary is often practised in English as a Second Language (ESL classrooms, it has been proven to be rather ineffective, largely because words are not taught in context. This has prompted the increasing use of incidental vocabulary learning approach, which emphasises on repeated readings as a source for vocabulary learning. By adopting this approach, this study aims to investigate students’ ability in learning vocabulary incidentally via verbal dramatization of written texts. In this case, readers’ theatre (RT is used as a way to allow learners to engage in active reading so as to promote vocabulary learning. A total of 160 diploma students participated in this case study and they were divided equally into two groups, namely classroom reading (CR and RT groups. A proficiency test was first conducted to determine their vocabulary levels. Based on the test results, a story was selected as the reading material in the two groups. The CR group read the story through a normal reading lesson in class while the RT group was required to verbally dramatize the text through readers’ theatre activity. Then, a post-test based on vocabulary levels was carried out and the results were compared. The findings revealed that incidental learning was more apparent in the RT group and their ability to learn words from the higher levels was noticeable through higher accuracy scores. Although not conclusive, this study has demonstrated the potential of using readers’ theatre as a form of incidental vocabulary learning activity in ESL settings.

  7. Risk of appendicitis in patients with incidentally discovered appendicoliths.

    Science.gov (United States)

    Khan, Muhammad Sohaib; Chaudhry, Mustafa Belal Hafeez; Shahzad, Noman; Tariq, Marvi; Memon, Wasim Ahmed; Alvi, Abdul Rehman

    2018-01-01

    An appendicolith-related appendiceal obstruction leading to appendicitis is a commonly encountered surgical emergency that has clear evidence-based management plans. However, there is no consensus on management of asymptomatic patients when appendicoliths are found incidentally. The objective of this study was to determine the risk of appendicitis in patients with an incidental finding of the appendicolith. A retrospective matched cohort study of patients with appendicolith discovered incidentally on computed tomographic scan from January 2008 to December 2014 at our institution was completed. The size and position of the appendicolith were ascertained. The study group was matched by age and gender to a control group. Both groups were contacted and interviewed regarding development of appendicitis. In total, 111 patients with appendicolith were successfully contacted and included in the study. Mean age was found to be 38 ± 15 y with 36 (32%) of the study population being females. Mean length of appendix was 66 ± 16 mm, and mean width was 5.8 ± 0.9 mm. Mean size of the appendicolith was 3.6 ± 1.1 mm (1.4-7.8 mm). Fifty-eight percent of appendicoliths was located at the proximal end or whole of appendix, 31% at mid area, and 11% at the distal end of appendix. All patients of the study and control groups were contacted, and at a mean follow-up of 4.0 ± 1.7 y, there was no occurrence of acute appendicitis in either group. Patients with incidentally discovered appendicolith on radiological imaging did not develop appendicitis. Hence, the risk of developing acute appendicitis for these patients does not seem higher than the general population. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Incidental gallbladder cancer: what management?

    Directory of Open Access Journals (Sweden)

    Sidi Mohammed Bouchentouf

    2011-11-01

    Full Text Available Gallbladder cancer (GBC represents 3.8% of all gastrointestinal cancers and usually known to be of a poor prognosis. In 0.2–2.9% of cases, this cancer is found in cholecystectomy specimens. A better understanding of spread mode of this tumor helps a better surgical management. The aim of the present review is to underline the management of GBC based on the comprehension of risk factors and anatomic features. A Medline, PubMed database search was performed to identify articles published from 2000 to 2011 using the keywords ‘carcinoma of gallbladder’, ‘incidental gallbladder cancer’, ‘gallbladder neoplasm’ and ‘cholecystectomy’. Some pathological situations such as chronic lithiasis and biliopancreatic junction abnormalities have been clearly identified as predisposing to GBC. Laparoscopy increases peritoneal and parietal tumor dissemination, thus, it should not be performed when GBC is suspected. Most determinant prognostic factors are nodal, perineural and venous involvement, invasion of the cystic duct and the tumor differentiation. The simple cholecystectomy is sufficient for tumors classified as T1a; for other cancers exceeding the muscularis, radical re-resection is required due to the high risk of recurrence. This aggressive surgery improved the overall survival of patients. There is still no standard adjuvant treatment; patients should be included in prospective trials.

  9. Mutations in LCA5, encoding the ciliary protein lebercilin, cause Leber congenital amaurosis.

    NARCIS (Netherlands)

    Hollander, A.I. den; Koenekoop, R.K.; Mohamed, M.D.; Arts, H.H.; Boldt, K.; Towns, K.V.; Sedmak, T.; Beer, M. de; Nagel-Wolfrum, K.; McKibbin, M.; Dharmaraj, S.; Lopez, I.; Ivings, L.; Williams, G.A.; Springell, K.; Woods, C.G.; Jafri, H.; Rashid, Y.; Strom, T.M.; Zwaag, B. van der; Gosens, I.; Kersten, F.F.J.; Wijk, E. van; Veltman, J.A.; Zonneveld, M.N.; Beersum, S.E.C. van; Maumenee, I.H.; Wolfrum, U.; Cheetham, M.E.; Ueffing, M.; Cremers, F.P.M.; Inglehearn, C.F.; Roepman, R.

    2007-01-01

    Leber congenital amaurosis (LCA) causes blindness or severe visual impairment at or within a few months of birth. Here we show, using homozygosity mapping, that the LCA5 gene on chromosome 6q14, which encodes the previously unknown ciliary protein lebercilin, is associated with this disease. We

  10. Involvement of LCA5 in Leber congenital amaurosis and retinitis pigmentosa in the Spanish population

    NARCIS (Netherlands)

    Corton, M.; Avila-Fernandez, A.; Vallespin, E.; Lopez-Molina, M.I.; Almoguera, B.; Martin-Garrido, E.; Tatu, S.D.; Khan, M.I.; Blanco-Kelly, F.; Riveiro-Alvarez, R.; Brion, M.; Garcia-Sandoval, B.; Cremers, F.P.M.; Carracedo, A.; Ayuso, C.

    2014-01-01

    OBJECTIVE: We aimed to identify novel genetic defects in the LCA5 gene underlying Leber congenital amaurosis (LCA) in the Spanish population and to describe the associated phenotype. DESIGN: Case series. PARTICIPANTS: A cohort of 217 unrelated Spanish families affected by autosomal recessive or

  11. From LCC to LCA Using a Hybrid Input Output Model – A Maritime Case Study

    DEFF Research Database (Denmark)

    Kjær, Louise Laumann; Pagoropoulos, Aris; Hauschild, Michael Zwicky

    2015-01-01

    As companies try to embrace life cycle thinking, Life Cycle Assessment (LCA) and Life Cycle Costing (LCC) have proven to be powerful tools. In this paper, an Environmental Input-Output model is used for analysis as it enables an LCA using the same economic input data as LCC. This approach helps...

  12. Differences of Longitudinal Chromatic Aberration (LCA) between Eyes with Intraocular Lenses from Different Manufacturers

    Science.gov (United States)

    Nakajima, Masashi; Hiraoka, Takahiro; Yamamoto, Toshiya; Takagi, Seiu; Hirohara, Yoko; Oshika, Tetsuro

    2016-01-01

    Several researchers have studied the longitudinal chromatic aberration (LCA) of eyes implanted with an intraocular lens (IOL). We investigated the LCA of eyes implanted with yellow-colored IOLs from three different manufacturers: Alcon Inc., HOYA Corp., and AMO Inc. The number of subjects was 11, 16, and 16, respectively. The LCA of eyes implanted with SN60WF and SN60AT (Alcon Inc.), and with XY-1 (HOYA Corp.), was the same as that of phakic eyes. The LCA of eyes with ZCB00V (AMO Inc.) was smaller than that of phakic eyes. The LCA of eyes implanted with Alcon’s and HOYA’s IOLs, but not the LCA of eyes implanted with AMO’s IOLs, was positively correlated with the powers of the IOLs. We also performed simulations to verify the impacts of LCA on visual performance for 4-mm pupil diameter; the simulations were a polychromatic modulation transfer function (MTF) and a visual Strehl ratio computed on the basis of an optical transfer function (VSOTF). We concluded that the differences between the LCA of different manufacturers do not affect visual performances when some extent of higher-order aberration (HOA) exists. The smaller HOA of AMO IOLs may enhance visual performance. PMID:27258141

  13. The Glasgow consensus on the delineation between pesticide emission inventory and impact assessment for LCA

    DEFF Research Database (Denmark)

    Rosenbaum, Ralph K.; Anton, Assumpció; Bengoa, Xavier

    2015-01-01

    Pesticides are applied to agricultural fields to optimise crop yield and their global use is substantial. Their consideration in life cycle assessment (LCA) is affected by important inconsistencies between the emission inventory and impact assessment phases of LCA. A clear definition...

  14. How methodological choices affect LCA climate impact results: the case of structural timber

    DEFF Research Database (Denmark)

    De Rosa, Michele; Pizzol, Massimo; Schmidt, Jannick

    2018-01-01

    Purpose Life cycle assessment (LCA) is broadly applied to assess the environmental impact of products through their life cycle. LCA of bio-based products is particularly challenging due to the uncertainties in modeling the natural biomass production process. While uncertainties related to invento...

  15. The value of the exergetic life cycle assessment besides the LCA

    NARCIS (Netherlands)

    Cornelissen, Rene; Hirs, Gerard

    2002-01-01

    In this paper the value of the exergetic life cycle assessment (ELCA) has been analysed. The ELCA uses the framework of the life cycle assessment (LCA) and can be seen as the exergy analysis of a complete life cycle. The value of the ELCA besides the LCA has been discussed. It is shown that the ELCA

  16. The complexity and challenges of determining GHG (greenhouse gas) emissions from grid electricity consumption and conservation in LCA (life cycle assessment) – A methodological review

    International Nuclear Information System (INIS)

    Soimakallio, Sampo; Kiviluoma, Juha; Saikku, Laura

    2011-01-01

    The way in which GHG (greenhouse gas) emissions associated with grid electricity consumption is handled in different LCA (life cycle assessment) studies, varies significantly. Apart from differences in actual research questions, methodological choices and data set selection have a significant impact on the outcomes. These inconsistencies result in difficulties to compare the findings of various LCA studies. This review paper explores the issue from a methodological point of view. The perspectives of ALCA (attributional life cycle assessment) and CLCA (consequential life cycle assessment) are reflected. Finally, the paper summarizes the key issues and provides suggestions on the way forward. The major challenge related to both of the LCA categories is to determine the GHG emissions of the power production technologies under consideration. Furthermore, the specific challenge in ALCA is to determine the appropriate electricity production mix, and in CLCA, to identify the marginal technologies affected and related consequences. Significant uncertainties are involved, particularly in future-related LCAs, and these should not be ignored. Harmonization of the methods and data sets for various purposes is suggested, acknowledging that selections might be subjective. -- Highlights: ► Methods to assess GHG emissions from grid electricity consumption in LCA vary. ► We explored the major challenges related to various methods. ► Significant uncertainties are involved particularly in future-related GHG emissions. ► The most appropriate method depends on the equity viewpoints.

  17. Characterisation of social impacts in LCA. Part 1: Development of indicators for labour rights

    DEFF Research Database (Denmark)

    Dreyer, Louise Camilla; Hauschild, Michael Zwicky; Schierbeck, Jens

    2010-01-01

    dignity and well-being as the ultimate goal and area of protection of Social LCA. The intended main application of this framework for Social LCA was to support management decisions in companies who wish to conduct business in a socially responsible manner, by providing information about the potential...... social impacts on people caused by the activities in the life cycle of a product. Environmental LCA normally uses quantitative and comparable indicators to provide a simple representation of the environmental impacts from the product lifecycle. This poses a challenge to the Social LCA framework because......Background, Aim and Scope The authors have earlier suggested a framework for life cycle impact assessment (LCIA) to form the modelling basis of Social LCA. In this framework the fundamental labour rights were pointed out as obligatory issues to be addressed, and protection and promotion of human...

  18. Energy system analysis of marginal electricity supply in consequential LCA

    DEFF Research Database (Denmark)

    Lund, Henrik; Mathiesen, Brian Vad; Christensen, Per

    2010-01-01

    Background, aim and scope This paper discusses the identification of the environmental consequences of marginal electricity supplies in consequential life cycle assessments (LCA). According to the methodology, environmental characteristics can be examined by identifying affected activities, i...... in capacity but can be characterised as a complex set of affected electricity and heat supply technologies. A long-term YAM technology is identified for the Danish BAU2030 system in the case of three different long-term marginal changes in capacity, namely coal, natural gas or wind power. Discussion Four...... of four different situations are provided. We suggest that the technology mix with the installation of natural gas or coal power plant is applied as the marginal capacity. Conclusions The environmental consequences of marginal changes in electricity supply cannot always be represented solely by long...

  19. Roadmap toward addressing and communicating uncertainty in LCA

    DEFF Research Database (Denmark)

    Laurin, Lise; Vigon, Bruce; Fantke, Peter

    2017-01-01

    -characterized uncertainty. The group has investigated current best LCA practices, such as refinements to the pedigree matrix used to assess LCI data quality. In parallel, in the frame of UNEP-SETAC Life Cycle Initiative flagship project on providing Harmonization and Global Guidance for Environmental Life Cycle Impact...... uncertainty is further related to input data, model selection and choices, amongst other aspects. Currently, methods exist to assess and assign uncertainty and variability on LCI data as well as LCIA characterization results. However, often uncertainty is only assessed and reported qualitatively......, is not comparable across impact categories and not consistently assessed and reported across levels of detail. Furthermore, many existing methods and models do not report uncertainty at all or limit their uncertainty assessment to a sensitivity analysis of selected input parameters, while ignoring variability...

  20. LCA and economic evaluation of landfill leachate and gas technologies

    DEFF Research Database (Denmark)

    Damgaard, Anders; Manfredi, Simone; Merrild, Hanna Kristina

    2011-01-01

    Landfills receiving a mix of waste, including organics, have developed dramatically over the last 3–4 decades; from open dumps to engineered facilities with extensive controls on leachate and gas. The conventional municipal landfill will in most climates produce a highly contaminated leachate...... and a significant amount of landfill gas. Leachate controls may include bottom liners and leachate collection systems as well as leachate treatment prior to discharge to surface water. Gas controls may include oxidizing top covers, gas collection systems with flares or gas utilization systems for production...... of electricity and heat.The importance of leachate and gas control measures in reducing the overall environmental impact from a conventional landfill was assessed by life-cycle-assessment (LCA). The direct cost for the measures were also estimated providing a basis for assessing which measures are the most cost...

  1. Compostable cutlery and waste management: an LCA approach.

    Science.gov (United States)

    Razza, Francesco; Fieschi, Maurizio; Innocenti, Francesco Degli; Bastioli, Catia

    2009-04-01

    The use of disposable cutlery in fast food restaurants and canteens in the current management scenario generates mixed heterogeneous waste (containing food waste and non-compostable plastic cutlery). The waste is not recyclable and is disposed of in landfills or incinerated with or without energy recovery. Using biodegradable and compostable (B&C) plastic cutlery, an alternative management scenario is possible. The resulting mixed homogeneous waste (containing food waste and compostable plastic cutlery) can be recycled through organic recovery, i.e., composting. This LCA study, whose functional unit is "serving 1000 meals", shows that remarkable improvements can be obtained by shifting from the current scenario to the alternative scenario (based on B&C cutlery and final organic recovery of the total waste). The non-renewable energy consumption changes from 1490 to 128MJ (an overall 10-fold energy savings) and the CO(2) equivalents emission changes from 64 to 22 CO(2) eq. (an overall 3-fold GHG savings).

  2. LCA and external costs in comparative assessment of electricity chains. Decision support for sustainable electricity provision?

    International Nuclear Information System (INIS)

    Voss, A.

    2002-01-01

    The provision of energy and electricity plays an important role in a country's economic and environmental performance and the sustainability of its development. Sustainable development of the energy and electricity sector depends on finding ways of meeting energy service demands of the present generation that are economically viable, environmentally sound, and socially acceptable and do not jeopardize the ability of future generations to meet their own energy needs. Life Cycle Assessment (LCA) and external cost valuation are considered to offer opportunities to assist energy policy in a comprehensive comparative evaluation of electricity supply options with regard to the different dimensions of sustainable energy provision as well as in the implementation of appropriate internalization strategies. The paper addresses life cycle assessment and external cost analysis carried out for selected electricity systems of interest under German conditions. Results from a comprehensive comparative assessment of various electricity supply options with regard to their environmental impacts, health risks, raw materials requirements as well as their resulting external cost will be summarised. The use of LCA based indicators for assessing the relative sustainability of electricity systems and the use of total (internal plus external) cost assessment as measure of economic and environmental efficiency of energy systems will be discussed. Open problems related to life cycle analysis of energy chains and the assessment of environmental damage costs are critically reviewed, to illustrate how in spite of existing uncertainties the state of the art results may provide helpful energy policy decision support. The paper starts with some remarks on what the concept of sustainability in terms of energy systems means. (author)

  3. Incidental copy-number variants identified by routine genome testing in a clinical population

    Science.gov (United States)

    Boone, Philip M.; Soens, Zachry T.; Campbell, Ian M.; Stankiewicz, Pawel; Cheung, Sau Wai; Patel, Ankita; Beaudet, Arthur L.; Plon, Sharon E.; Shaw, Chad A.; McGuire, Amy L.; Lupski, James R.

    2013-01-01

    Purpose Mutational load of susceptibility variants has not been studied on a genomic scale in a clinical population, nor has the potential to identify these mutations as incidental findings during clinical testing been systematically ascertained. Methods Array comparative genomic hybridization, a method for genome-wide detection of DNA copy-number variants, was performed clinically on DNA from 9,005 individuals. Copy-number variants encompassing or disrupting single genes were identified and analyzed for their potential to confer predisposition to dominant, adult-onset disease. Multigene copy-number variants affecting dominant, adult-onset cancer syndrome genes were also assessed. Results In our cohort, 83 single-gene copy-number variants affected 40 unique genes associated with dominant, adult-onset disorders and unrelated to the patients’ referring diagnoses (i.e., incidental) were found. Fourteen of these copy-number variants are likely disease-predisposing, 25 are likely benign, and 44 are of unknown clinical consequence. When incidental copy-number variants spanning up to 20 genes were considered, 27 copy-number variants affected 17 unique genes associated with dominant, adult-onset cancer predisposition. Conclusion Copy-number variants potentially conferring susceptibility to adult-onset disease can be identified as incidental findings during routine genome-wide testing. Some of these mutations may be medically actionable, enabling disease surveillance or prevention; however, most incidentally observed single-gene copy-number variants are currently of unclear significance to the patient. PMID:22878507

  4. How could disclosing incidental information from whole-genome sequencing affect patient behavior?

    Science.gov (United States)

    Christensen, Kurt D; Green, Robert C

    2013-06-01

    In this article, we argue that disclosure of incidental findings from whole-genome sequencing has the potential to motivate individuals to change health behaviors through psychological mechanisms that differ from typical risk assessment interventions. Their ability to do so, however, is likely to be highly contingent upon the nature of the incidental findings and how they are disclosed, the context of the disclosure and the characteristics of the patient. Moreover, clinicians need to be aware that behavioral responses may occur in unanticipated ways. This article argues for commentators and policy makers to take a cautious but optimistic perspective while empirical evidence is collected through ongoing research involving whole-genome sequencing and the disclosure of incidental information.

  5. Large Eustachian valve: An incidental finding yet perplexing

    Directory of Open Access Journals (Sweden)

    Anju Sarupria

    2014-01-01

    Full Text Available Eustachian valve (EV, a remnant of the right valve of sinus venosus in the right atrium can be puzzling. Often it is confused with Chiari network or atrial adhesions and is reported with unusual complications. We report a case of large EV impeding cannulation of inferior vena cava (IVC during aortic valve replacement. Transesophageal echocardiography diagnosed the presence of large EV and warned of the difficulty with IVC cannulation and helped preparedness for an alternative plan during surgery.

  6. CASE SERIES Substantive incidental cardiac findings revealed by ...

    African Journals Online (AJOL)

    For years, the technological limitations inherent in CT imaging of the thorax meant that the heart was an ill-defined and largely ignored. 'space-filler' between the lungs. With the advent of multi-detector CT scanning (MDCT) in the late 1990s, and shortened imaging times, it has now become possible to clearly identify cardiac ...

  7. Incidental findings of Cysticercus tenuicollis metacestodes in five oryx species

    Directory of Open Access Journals (Sweden)

    Stephen Chege

    2016-01-01

    Conclusions: This study shows that, Arabian oryx, beisa oryx, fringe-eared oryx, gemsbok and scimitar-horned oryx are susceptible to C. tenuicollis. Based on the epidemiology and the life cycle of this parasite, it is possible that these captive animals ingested the parasite through contaminated feed which could have happened in the pasture land or stray dogs and wild canidae (e.g. fox visited the zoo contaminating the oryx feed. Stray dogs and wild canidae should be prevented from visiting pasture land and a captive animal facility.

  8. Case Report on Septate Uterus: An Incidental Finding in a ...

    African Journals Online (AJOL)

    Background: Septate uterus is caused by incomplete resorption of the Mullerian duct during embryogenesis which may alter the reproductive outcome of the patients. It is the commonest form of structural uterine anomaly and has the highest reproductive failure rate. Case Report: A 21-year-old booked G4P2. +1 woman with ...

  9. Antithyroperoxidase Antibodies in Encephalopathy : Diagnostic Marker or Incidental Finding?

    NARCIS (Netherlands)

    Dontje, B.; Van Santen, H. M.; Niermeijer, J. M.; Schonenberg-Meinema, D.; Van Trotsenburg, A. S P

    2016-01-01

    Patients with acute encephalopathy who are thoroughly examined for an underlying diagnosis and in whom infectious, metabolic, and malignant causes are excluded can form a true diagnostic dilemma. If antithyroperoxidase antibodies (anti-TPO abs) are present, the diagnosis steroid responsive

  10. POLAND' SYNDROME: An Incidental findings on routine medical ...

    African Journals Online (AJOL)

    Dr Hamidu

    SM is a 20 year, old young man who came for routine medical check for recruitment into a local football club. Born to a 45 ... mimicking a radical mastectomy. A dense ascending line as a result of the absence of the ... centered around reconstructive surgical procedures on the hand. They may however be some functional.

  11. 77 FR 17037 - Intent To Prepare a Draft Environmental Impact Statement for the Louisiana Coastal Area (LCA...

    Science.gov (United States)

    2012-03-23

    ... Environmental Impact Statement for the Louisiana Coastal Area (LCA)--Louisiana, Mississippi River Hydrodynamic... impact statement (EIS) for the Louisiana Coastal Area (LCA)--Louisiana, Mississippi River Hydrodynamic... tiered off of the November 2004, programmatic EIS for the Louisiana Coastal Area (LCA), Louisiana...

  12. The significance of incidental focal colonic 18FDG uptake on PET scanning

    International Nuclear Information System (INIS)

    Bartholomeusz, Dylan; Schultz, Christopher

    2009-01-01

    Full text: The incidental discovery of colonic polyps, colonic malignancy, diverticulitis and inflammation during PET scanning is well described. This study is a retrospective review of the incidence and follow up of incidental focal FOG uptake in the colon detected during routine PET scanning. PET scan reports over 12 months were reviewed for the reporting of incidental colonic uptake and then clinical follow up performed in available patient records for the incidence of further colonic investigation and results. In 2008, 1985 PET scans were reported at the Royal Adelaide Hospital for the staging and detection of malignancy. Review of the results show that incidental focal colonic uptake was seen in 27 cases, (II female aged 56-83 years). Follow up colonoscopy was performed in 8 cases and in 4 cases showed tubulovillous adenomas, 7-9 mm in size, in the region of abnormal FOG uptake, I had divetticulae and another focal inflammation. Two colonoscopies revealed no abnormality (25% false negative rate). One patient with Head and Neck cancer did not have colonoscopy but the colonic lesion resolved on a post therapy PET scan. Of the 18 cases that did not have colonoscopic follow up 5 were reported on the PET scan to have diffuse probably physiological caecal activity but 13 had focal lesions in the large bowel. Although incidental colonic lesions were detected in only 1.3% of studies, of those having colonoscopy 75 % had significant findings.

  13. Trends in port-site metastasis after laparoscopic resection of incidental gallbladder cancer: A systematic review.

    Science.gov (United States)

    Berger-Richardson, David; Chesney, Tyler R; Englesakis, Marina; Govindarajan, Anand; Cleary, Sean P; Swallow, Carol J

    2017-03-01

    The risk of port-site metastasis after laparoscopic removal of incidental gallbladder cancer was previously estimated to be 14-30%. The present study was designed to determine the incidence of port-site metastasis in incidental gallbladder cancer in the modern era (2000-2014) versus the historic era (1991-1999). We also investigated the site of port-site metastasis. Using PRISMA, a systematic review was conducted to identify papers that addressed the development of port-site metastasis after laparoscopic resection of incidental gallbladder cancer. Studies that described cancer-specific outcomes in ≥5 patients were included. A validated quality appraisal tool was used, and a weighted estimate of the incidence of port-site metastasis was calculated. Based on data extracted from 27 papers that met inclusion criteria, the incidence of port-site metastasis in incidental gallbladder cancer has decreased from 18.6% prior to 2000 (95% confidence interval 15.3-21.9%, n = 7) to 10.3% since then (95% confidence interval 7.9-12.7%, n = 20) (P extraction site is at significantly higher risk than nonextraction sites. The incidence of port-site metastasis in incidental gallbladder cancer has decreased but remains high relative to other primary tumors. Any preoperative finding that raises the suspicion of gallbladder cancer should prompt further investigation and referral to a hepato-pancreato-biliary specialist. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Effects of Incidental Emotions on Moral Dilemma Judgments: An Analysis Using the CNI Model.

    Science.gov (United States)

    Gawronski, Bertram; Conway, Paul; Armstrong, Joel; Friesdorf, Rebecca; Hütter, Mandy

    2018-02-01

    Effects of incidental emotions on moral dilemma judgments have garnered interest because they demonstrate the context-dependent nature of moral decision-making. Six experiments (N = 727) investigated the effects of incidental happiness, sadness, and anger on responses in moral dilemmas that pit the consequences of a given action for the greater good (i.e., utilitarianism) against the consistency of that action with moral norms (i.e., deontology). Using the CNI model of moral decision-making, we further tested whether the three kinds of emotions shape moral dilemma judgments by influencing (a) sensitivity to consequences, (b) sensitivity to moral norms, or (c) general preference for inaction versus action regardless of consequences and moral norms (or some combination of the three). Incidental happiness reduced sensitivity to moral norms without affecting sensitivity to consequences or general preference for inaction versus action. Incidental sadness and incidental anger did not show any significant effects on moral dilemma judgments. The findings suggest a central role of moral norms in the contribution of emotional responses to moral dilemma judgments, requiring refinements of dominant theoretical accounts and supporting the value of formal modeling approaches in providing more nuanced insights into the determinants of moral dilemma judgments. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  15. Sources Of Incidental Events In Collective Water Supply System

    Directory of Open Access Journals (Sweden)

    Szpak Dawid

    2015-11-01

    Full Text Available The publication presents the main types of incidental events in collective water supply system. The special attention was addressed to the incidental events associated with a decrease in water quality, posing a threat to the health and life of inhabitants. The security method against incidental contamination in the water source was described.

  16. IAQ performance of interior finishing products and the role of LCA

    CSIR Research Space (South Africa)

    Ampofo-Anti, N

    2010-01-01

    Full Text Available of interior finishing products to be more performance-oriented, where performance is defined in terms of the life cycle human health effects 4 . 3.0 LCA – the science-based tool Life Cycle Assessment (LCA) is a science-based tool which is designed... of interior finishing products and the role of LCA Naalamkai Ampofo-Anti, Senior Researcher, CSIR 1.0 Introduction The environmental rating and certification of products is a voluntary, market-based response by industry and business to the consumer’s...

  17. LCA and economic evaluation of landfill leachate and gas technologies.

    Science.gov (United States)

    Damgaard, Anders; Manfredi, Simone; Merrild, Hanna; Stensøe, Steen; Christensen, Thomas H

    2011-07-01

    Landfills receiving a mix of waste, including organics, have developed dramatically over the last 3-4 decades; from open dumps to engineered facilities with extensive controls on leachate and gas. The conventional municipal landfill will in most climates produce a highly contaminated leachate and a significant amount of landfill gas. Leachate controls may include bottom liners and leachate collection systems as well as leachate treatment prior to discharge to surface water. Gas controls may include oxidizing top covers, gas collection systems with flares or gas utilization systems for production of electricity and heat. The importance of leachate and gas control measures in reducing the overall environmental impact from a conventional landfill was assessed by life-cycle-assessment (LCA). The direct cost for the measures were also estimated providing a basis for assessing which measures are the most cost-effective in reducing the impact from a conventional landfill. This was done by modeling landfills ranging from a simple open dump to highly engineered conventional landfills with energy recovery in form of heat or electricity. The modeling was done in the waste LCA model EASEWASTE. The results showed drastic improvements for most impact categories. Global warming went from an impact of 0.1 person equivalent (PE) for the dump to -0.05 PE for the best design. Similar improvements were found for photochemical ozone formation (0.02 PE to 0.002 PE) and stratospheric ozone formation (0.04 PE to 0.001 PE). For the toxic and spoiled groundwater impact categories the trend is not as clear. The reason for this was that the load to the environment shifted as more technologies were used. For the dump landfill the main impacts were impacts for spoiled groundwater due to lack of leachate collection, 2.3 PE down to 0.4 PE when leachate is collected. However, at the same time, leachate collection causes a slight increase in eco-toxicity and human toxicity via water (0.007 E to 0

  18. Incidental transients problems in reactor. Application examples

    International Nuclear Information System (INIS)

    Marbach, G.

    1988-03-01

    The fast neutron reactor fuel element qualification should be made not only for nominal operation but also for incidental and accidental transients. Different studies and tests permit to bring this justification such as simulation in hot laboratory after irradiation of irradiated pins or specific tests interpretation [fr

  19. Incidental learning in second language acquisition

    NARCIS (Netherlands)

    Hulstijn, J.H.; Chapelle, C.A.

    2013-01-01

    The term incidental learning is used, in applied linguistics, to refer to the acquisition of a word or expression without the conscious intention to commit the element to memory, such as "picking up" an unknown word from listening to someone or from reading a text.

  20. Incidental diagnosis of diseases on un-enhanced helical computed tomography performed for ureteric colic

    Directory of Open Access Journals (Sweden)

    Ather M Hammad

    2003-03-01

    Full Text Available Abstract Background Patients presenting in the emergency room with flank pain suggestive of acute ureteric colic may have alternative underlying conditions mimicking ureteric stones. An early diagnosis and appropriate treatment for other causes of flank pain is important. The majority of centers around the world are increasingly using un-enhanced helical CT (UHCT for evaluation of ureteric colic. This study was conducted to determine the incidence and spectrum of significant incidental diagnoses established or suggested on UHCT performed for suspected renal/ureteric colic. Methods Urologist and radiologist reviewed 233 consecutive UHCT, performed for suspected renal/ureteral colic along with assessment of the medical records. Radiological diagnoses of clinical entities not suspected otherwise were analyzed. All other relevant radiological, biochemical and serological investigations and per-operative findings were also noted. Results Ureteral calculi were identified in 148 examinations (64%, findings of recent passage of calculi in 10 (4% and no calculus in 75 examinations (32%. Overall the incidental findings (additional or alternative diagnosis were found in 28 (12% CT scans. Twenty (71% of these diagnoses were confirmed by per-operative findings, biopsy, and other radiological and biochemical investigations or on clinical follow up. Conclusion A wide spectrum of significant incidental diagnoses can be identified on UHCT performed for suspected renal/ureteral colic. In the present series of 233 consecutive CT examinations, the incidence of incidental diagnosis was 12%.

  1. Evaluation of the Significance of Incidental Breast Lesions Detected by Chest CT

    International Nuclear Information System (INIS)

    Kim, Jae Hyun; Chang, Yun Woo; Hwang, Jung Hwa; Kim, Hyung Hwan; Lee, Eun Hye; Yang, Seung Boo

    2013-01-01

    To evaluate the significance of incidentally detected breast lesions on a chest CT scan. Thirty-six incidental breast lesions in 26 patients were detected on a chest CT scan and were correlated with breast sonography, retrospectively. Among them, twenty-four breast lesions in 20 patients that were correlated with chest CT and sonography were available to pathology or follow up sonography. The CT findings were compared with sonographic findings according to the pathologic results. Incidentally detected breast lesions on a chest CT scan were correlated with sonography in 86% (31/36). Among 24 lesions that were available to pathology or follow up sonography, seven (29.2%) lesions were malignant and 17 (70.8%) lesions were benign. CT revealed a significant difference between benign and malignant lesions in terms of shape and margin (p = 0.007; p = 0.008, respectively). The CT findings were well correlated with sonographic findings in shape and margin (p = 0.001, respectively). Incidentally detected breast lesions on chest CT can be correlated with sonography. An irregular shape or a non-circumscribed margin of breast lesions on a CT scan can be considered as a suggestive sign of malignancy.

  2. 76 FR 73600 - Taking and Importing Marine Mammals; Taking Marine Mammals Incidental to Missile Launch...

    Science.gov (United States)

    2011-11-29

    ... years if NMFS finds, after notification and opportunity for public comment, that the taking will have a... taking. Regulations governing the taking of northern elephant seals (Mirounga angustirostris), Pacific... a period not to exceed 1 year, take of pinnipeds, by harassment, incidental to missile launch...

  3. 75 FR 28587 - Taking and Importing Marine Mammals; Taking Marine Mammals Incidental to Missile Launch...

    Science.gov (United States)

    2010-05-21

    ... granted for periods up to 5 years if NMFS finds, after notification and opportunity for public comment... such taking. Regulations governing the taking of northern elephant seals (Mirounga angustirostris... would authorize, for a period not to exceed 1 year, take of pinnipeds, by harassment, incidental to...

  4. LCA Study of Oleaginous Bioenergy Chains in a Mediterranean Environment

    Directory of Open Access Journals (Sweden)

    Daniele Cocco

    2014-09-01

    Full Text Available This paper reports outcomes of life cycle assessments (LCAs of three different oleaginous bioenergy chains (oilseed rape, Ethiopian mustard and cardoon under Southern Europe conditions. Accurate data on field practices previously collected during a three-year study at two sites were used. The vegetable oil produced by oleaginous seeds was used for power generation in medium-speed diesel engines while the crop residues were used in steam power plants. For each bioenergy chain, the environmental impact related to cultivation, transportation of agricultural products and industrial conversion for power generation was evaluated by calculating cumulative energy demand, acidification potential and global warming potential. For all three bioenergy chains, the results of the LCA study show a considerable saving of primary energy (from 70 to 86 GJ·ha−1 and greenhouse gas emissions (from 4.1 to 5.2 t CO2·ha−1 in comparison to power generation from fossil fuels, although the acidification potential of these bioenergy chains may be twice that of conventional power generation. In addition, the study highlights that land use changes due to the cultivation of the abovementioned crops reduce soil organic content and therefore worsen and increase greenhouse gas emissions for all three bioenergy chains. The study also demonstrates that the exploitation of crop residues for energy production greatly contributes to managing environmental impact of the three bioenergy chains.

  5. Assessing the environmental impacts of freshwater consumption in LCA.

    Science.gov (United States)

    Pfister, Stephan; Koehler, Annette; Hellweg, Stefanie

    2009-06-01

    A method for assessing the environmental impacts of freshwater consumption was developed. This method considers damages to three areas of protection: human health, ecosystem quality, and resources. The method can be used within most existing life-cycle impact assessment (LCIA) methods. The relative importance of water consumption was analyzed by integrating the method into the Eco-indicator-99 LCIA method. The relative impact of water consumption in LCIA was analyzed with a case study on worldwide cotton production. The importance of regionalized characterization factors for water use was also examined in the case study. In arid regions, water consumption may dominate the aggregated life-cycle impacts of cotton-textile production. Therefore, the consideration of water consumption is crucial in life-cycle assessment (LCA) studies that include water-intensive products, such as agricultural goods. A regionalized assessment is necessary, since the impacts of water use vary greatly as a function of location. The presented method is useful for environmental decision-support in the production of water-intensive products as well as for environmentally responsible value-chain management.

  6. LCA comparison of container systems in municipal solid waste management

    International Nuclear Information System (INIS)

    Rives, Jesus; Rieradevall, Joan; Gabarrell, Xavier

    2010-01-01

    The planning and design of integrated municipal solid waste management (MSWM) systems requires accurate environmental impact evaluation of the systems and their components. This research assessed, quantified and compared the environmental impact of the first stage of the most used MSW container systems. The comparison was based on factors such as the volume of the containers, from small bins of 60-80 l to containers of 2400 l, and on the manufactured materials, steel and high-density polyethylene (HDPE). Also, some parameters such as frequency of collections, waste generation, filling percentage and waste container contents, were established to obtain comparable systems. The methodological framework of the analysis was the life cycle assessment (LCA), and the impact assessment method was based on CML 2 baseline 2000. Results indicated that, for the same volume, the collection systems that use HDPE waste containers had more of an impact than those using steel waste containers, in terms of abiotic depletion, global warming, ozone layer depletion, acidification, eutrophication, photochemical oxidation, human toxicity and terrestrial ecotoxicity. Besides, the collection systems using small HDPE bins (60 l or 80 l) had most impact while systems using big steel containers (2400 l) had less impact. Subsequent sensitivity analysis about the parameters established demonstrated that they could change the ultimate environmental impact of each waste container collection system, but that the comparative relationship between systems was similar.

  7. Estimating pesticide emission fractions for use in LCA: A global consensus-building effort

    DEFF Research Database (Denmark)

    Fantke, Peter; Anton, Assumpcio; Basset-Mens, Claudine

    2016-01-01

    agreement on recommended default agricultural pesticide emission fractions to environmental media. Consensual decisions on the assessment framework are (a) primary distributions are used as inputs for LCIA, while further investigating how to assess secondary emissions, (b) framework and LCA application...... and application method scenarios will be based on sensitiv ity analysis, (g) default emission estimates for LCA will be derived from production-weighted averages, and (h) emission fractions will be reported spatially disaggregated. Recommendations for LCA practitioners and database developers are (a) LCA studies...... the field as part of technosphere and ecosphere, (e) fate and exposure processes should be included in LCIA (e.g. crop uptake), (f) default emission estimates should be used in absence of detailed scenario data, (g) and all assumptions should be reported. The recommended pesticide emission fractions results...

  8. LCA for assessing the environmental performance of a company with the environmental management system ISO 14000

    International Nuclear Information System (INIS)

    Rigamonti, L.; Perotto, E.

    2008-01-01

    The environmental management system is an ordered pattern to treat and manage environmental issues and to improve the environmental performance of companies. It is proposed an example of application of LCA to a manufacturing company with ISO 14000. [it

  9. Transportation life cycle assessment (LCA) synthesis : life cycle assessment learning module series.

    Science.gov (United States)

    2015-03-12

    The Life Cycle Assessment Learning Module Series is a set of narrated, self-advancing slideshows on : various topics related to environmental life cycle assessment (LCA). This research project produced the first 27 of such modules, which : are freely...

  10. Neonatal disease environment limits the efficacy of retinal transplantation in the LCA8 mouse model

    OpenAIRE

    Cho, Seo-Hee; Song, Ji Yun; Shin, Jinyeon; Kim, Seonhee

    2016-01-01

    Background Mutations of Crb1 gene cause irreversible and incurable visual impairment in humans. This study aims to use an LCA8-like mouse model to identify host-mediated responses that might interfere with survival, retinal integration and differentiation of grafted cells during neonatal cell therapy. Methods Mixed retinal donor cells (1?~?2???104) isolated from neural retinas of neonatal eGFP transgenic mice were injected into the subretinal space of LCA8-like model neonatal mice. Markers of...

  11. Incidental and clinically actionable genetic variants in 1005 whole exomes and genomes from Qatar

    Directory of Open Access Journals (Sweden)

    Abhinav Jain

    2017-10-01

    Full Text Available Next generation sequencing (NGS technologies such as whole genome and whole exome sequencing has enabled accurate diagnosis of genetic diseases through identification of variations at the genome wide level. While many large populations have been adequately covered in global sequencing efforts little is known on the genomic architecture of populations from Middle East, and South Asia and Africa. Incidental findings and their prevalence in populations have been extensively studied in populations of Caucasian descent. The recent emphasis on genomics and availability of genome-scale datasets in public domain for ethnic population in the Middle East prompted us to estimate the prevalence of incidental findings for this population. In this study, we used whole genome and exome data for a total 1005 non-related healthy individuals from Qatar population dataset which contained 20,930,177 variants. Systematic analysis of the variants in 59 genes recommended by the American College of Medical Genetics and Genomics for reporting of incidental findings revealed a total of 2 pathogenic and 2 likely pathogenic variants. Our analysis suggests the prevalence of incidental variants in population-scale datasets is approx. 0.6%, much lower than those reported for global populations. Our study underlines the essentiality to study population-scale genomes from ethnic groups to understand systematic differences in genetic variants associated with disease predisposition.

  12. The Role of Medial Temporal Lobe Regions in Incidental and Intentional Retrieval of Item and Relational Information in Aging.

    Science.gov (United States)

    Wang, Wei-Chun; Giovanello, Kelly S

    2016-06-01

    Considerable neuropsychological and neuroimaging work indicates that the medial temporal lobes are critical for both item and relational memory retrieval. However, there remain outstanding issues in the literature, namely the extent to which medial temporal lobe regions are differentially recruited during incidental and intentional retrieval of item and relational information, and the extent to which aging may affect these neural substrates. The current fMRI study sought to address these questions; participants incidentally encoded word pairs embedded in sentences and incidental item and relational retrieval were assessed through speeded reading of intact, rearranged, and new word-pair sentences, while intentional item and relational retrieval were assessed through old/new associative recognition of a separate set of intact, rearranged, and new word pairs. Results indicated that, in both younger and older adults, anterior hippocampus and perirhinal cortex indexed incidental and intentional item retrieval in the same manner. In contrast, posterior hippocampus supported incidental and intentional relational retrieval in both age groups and an adjacent cluster in posterior hippocampus was recruited during both forms of relational retrieval for older, but not younger, adults. Our findings suggest that while medial temporal lobe regions do not differentiate between incidental and intentional forms of retrieval, there are distinct roles for anterior and posterior medial temporal lobe regions during retrieval of item and relational information, respectively, and further indicate that posterior regions may, under certain conditions, be over-recruited in healthy aging. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  13. XSemantic: An Extension of LCA Based XML Semantic Search

    Science.gov (United States)

    Supasitthimethee, Umaporn; Shimizu, Toshiyuki; Yoshikawa, Masatoshi; Porkaew, Kriengkrai

    One of the most convenient ways to query XML data is a keyword search because it does not require any knowledge of XML structure or learning a new user interface. However, the keyword search is ambiguous. The users may use different terms to search for the same information. Furthermore, it is difficult for a system to decide which node is likely to be chosen as a return node and how much information should be included in the result. To address these challenges, we propose an XML semantic search based on keywords called XSemantic. On the one hand, we give three definitions to complete in terms of semantics. Firstly, the semantic term expansion, our system is robust from the ambiguous keywords by using the domain ontology. Secondly, to return semantic meaningful answers, we automatically infer the return information from the user queries and take advantage of the shortest path to return meaningful connections between keywords. Thirdly, we present the semantic ranking that reflects the degree of similarity as well as the semantic relationship so that the search results with the higher relevance are presented to the users first. On the other hand, in the LCA and the proximity search approaches, we investigated the problem of information included in the search results. Therefore, we introduce the notion of the Lowest Common Element Ancestor (LCEA) and define our simple rule without any requirement on the schema information such as the DTD or XML Schema. The first experiment indicated that XSemantic not only properly infers the return information but also generates compact meaningful results. Additionally, the benefits of our proposed semantics are demonstrated by the second experiment.

  14. Differences between LCA for analysis and LCA for policy : A case study on the consequences of allocation choices in bio-energy policies

    NARCIS (Netherlands)

    Wardenaar, T.; Van Ruijven, T.W.J.; Beltran, A.M.; Vad, K.; Guinee, J.; Heijungs, R.

    2012-01-01

    Purpose - The increasing concern for adverse effects of climate change has spurred the search for alternatives for conventional energy sources. Life cycle assessment (LCA) has increasingly been used to assess the potential of these alternatives to reduce greenhouse gas emissions. The popularity of

  15. Differences between LCA for analysis and LCA for policy : A case study on the consequences of allocation choices in bio-energy policies

    NARCIS (Netherlands)

    Wardenaar, Tjerk; Van Ruijven, Theo; Beltran, Angelica Mendoza; Vad, Kathrine; Guinée, Jeroen B.; Heijungs, Reinout

    Purpose: The increasing concern for adverse effects of climate change has spurred the search for alternatives for conventional energy sources. Life cycle assessment (LCA) has increasingly been used to assess the potential of these alternatives to reduce greenhouse gas emissions. The popularity of

  16. Prospective time-resolved LCA of fully electric supercap vehicles in Germany.

    Science.gov (United States)

    Zimmermann, Benedikt M; Dura, Hanna; Baumann, Manuel J; Weil, Marcel R

    2015-07-01

    The ongoing transition of the German electricity supply toward a higher share of renewable and sustainable energy sources, called Energiewende in German, has led to dynamic changes in the environmental impact of electricity over the last few years. Prominent scenario studies predict that comparable dynamics will continue in the coming decades, which will further improve the environmental performance of Germany's electricity supply. Life cycle assessment (LCA) is the methodology commonly used to evaluate environmental performance. Previous LCA studies on electric vehicles have shown that the electricity supply for the vehicles' operation is responsible for the major part of their environmental impact. The core question of this study is how the prospective dynamic development of the German electricity mix will affect the impact of electric vehicles operated in Germany and how LCA can be adapted to analyze this impact in a more robust manner. The previously suggested approach of time-resolved LCA, which is located between static and dynamic LCA, is used in this study and compared with several static approaches. Furthermore, the uncertainty issue associated with scenario studies is addressed in general and in relation to time-resolved LCA. Two scenario studies relevant to policy making have been selected, but a moderate number of modifications have been necessary to adapt the data to the requirements of a life cycle inventory. A potential, fully electric vehicle powered by a supercapacitor energy storage system is used as a generic example. The results show that substantial improvements in the environmental repercussions of the electricity supply and, consequentially, of electric vehicles will be achieved between 2020 and 2031 on the basis of the energy mixes predicted in both studies. This study concludes that although scenarios might not be able to predict the future, they should nonetheless be used as data sources in prospective LCA studies, because in many cases

  17. Global warming impact assessment of a crop residue gasification project—A dynamic LCA perspective

    International Nuclear Information System (INIS)

    Yang, Jin; Chen, Bin

    2014-01-01

    Highlights: • A dynamic LCA is proposed considering time-varying factors. • Dynamic LCA is used to highlight GHG emission hotspots of gasification projects. • Indicators are proposed to reflect GHG emission performance. • Dynamic LCA alters the static LCA results. • Crop residue gasification project has high GHG abatement potential. - Abstract: Bioenergy from crop residues is one of the prevailing sustainable energy sources owing to the abundant reserves worldwide. Amongst a wide variety of energy conversion technologies, crop residue gasification has been regarded as promising owing to its higher energy efficiency than that of direct combustion. However, prior to large-scale application of crop residue gasification, the lifetime environmental performance should be investigated to shed light on sustainable strategies. As traditional static life cycle assessment (LCA) does not include temporal information for dynamic processes, we proposed a dynamic life cycle assessment approach, which improves the static LCA approach by considering time-varying factors, e.g., greenhouse gas characterization factors and energy intensity. As the gasification project can reduce greenhouse gas (GHG) discharge compared with traditional direct fuel combustion, trade-offs between the benefits of global warming mitigation and the impact on global warming of crop residue gasification should be considered. Therefore, indicators of net global warming mitigation benefit and global warming impact mitigation period are put forward to justify the feasibility of the crop residue gasification project. The proposed dynamic LCA and indicators were then applied to estimate the life cycle global warming impact of a crop residue gasification system in China. Results show that the crop residue gasification project has high net global warming mitigation benefit and a short global warming impact mitigation period, indicating its prominent potential in alleviating global warming impact. During

  18. Broadening GHG accounting with LCA: application to a waste management business unit.

    Science.gov (United States)

    Fallaha, Sophie; Martineau, Geneviève; Bécaert, Valérie; Margni, Manuele; Deschênes, Louise; Samson, Réjean; Aoustin, Emmanuelle

    2009-11-01

    In an effort to obtain the most accurate climate change impact assessment, greenhouse gas (GHG) accounting is evolving to include life-cycle thinking. This study (1) identifies similarities and key differences between GHG accounting and life-cycle assessment (LCA), (2) compares them on a consistent basis through a case study on a waste management business unit. First, GHG accounting is performed. According to the GHG Protocol, annual emissions are categorized into three scopes: direct GHG emissions (scope 1), indirect emissions related to electricity, heat and steam production (scope 2) and other indirect emissions (scope 3). The LCA is then structured into a comparable framework: each LCA process is disaggregated into these three scopes, the annual operating activities are assessed, and the environmental impacts are determined using the IMPACT2002+ method. By comparing these two approaches it is concluded that both LCA and GHG accounting provide similar climate change impact results as the same major GHG contributors are determined for scope 1 emissions. The emissions from scope 2 appear negligible whereas emissions from scope 3 cannot be neglected since they contribute to around 10% of the climate change impact of the waste management business unit. This statement is strengthened by the fact that scope 3 generates 75% of the resource use damage and 30% of the ecosystem quality damage categories. The study also shows that LCA can help in setting up the framework for a annual GHG accounting by determining the major climate change contributors.

  19. Development of a Carbon Emission Calculations System for Optimizing Building Plan Based on the LCA Framework

    Directory of Open Access Journals (Sweden)

    Feifei Fu

    2014-01-01

    Full Text Available Life cycle thinking has become widely applied in the assessment for building environmental performance. Various tool are developed to support the application of life cycle assessment (LCA method. This paper focuses on the carbon emission during the building construction stage. A partial LCA framework is established to assess the carbon emission in this phase. Furthermore, five typical LCA tools programs have been compared and analyzed for demonstrating the current application of LCA tools and their limitations in the building construction stage. Based on the analysis of existing tools and sustainability demands in building, a new computer calculation system has been developed to calculate the carbon emission for optimizing the sustainability during the construction stage. The system structure and detail functions are described in this paper. Finally, a case study is analyzed to demonstrate the designed LCA framework and system functions. This case is based on a typical building in UK with different plans of masonry wall and timber frame to make a comparison. The final results disclose that a timber frame wall has less embodied carbon emission than a similar masonry structure. 16% reduction was found in this study.

  20. Incidental enhancing lesions found on preoperative breast MRI: management and role of second-look ultrasound.

    Science.gov (United States)

    Luciani, M L; Pediconi, F; Telesca, M; Vasselli, F; Casali, V; Miglio, E; Passariello, R; Catalano, C

    2011-09-01

    This study prospectively assessed second-look ultrasound (US) for the evaluation of incidental enhancing lesions identified on preoperative breast magnetic resonance imaging (MRI). Between 2004 and 2007, 182 patients with malignant breast lesions detected on US and/or X-ray mammography and confirmed by cytology/histology underwent preoperative breast contrast-enhanced (CE)-MRI. Patients with incidental lesions on breast MRI underwent second-look high-resolution US directed at the site of the incidental finding. Diagnosis of incidental lesions was based on biopsy or 24-month follow-up. Breast MRI detected 55 additional lesions in 46/182 (25.2%) patients. Forty-two of 55 (76.3%) lesions were detected on second-look US in 38/46 (82.6%) patients. Malignancy was confirmed for 24/42 (57.1%) correlate lesions compared with 7/13 (53.8%) noncorrelate lesions. Second-look US depicted 8/9 (88.8%) Breast Imaging Reporting and Data System (BI-RADS) 5, 16/22 (72.7%) BI-RADS 4 and 18/24 (75%) BI-RADS 3 lesions. Sensitivity, specificity, accuracy and positive and negative predictive values for lesion detection/diagnosis was 100%, 88.9%, 94.6%, 90.3% and 100% for MRI and 64.3%, 70.4%, 67.3%, 69.2% and 65.5% for second-look US. Improved performance for US was obtained when masslike lesions only were considered. Second-look US is a confirmatory method for incidental findings on breast MRI, particularly for mass-like lesions.

  1. Incidental internal carotid artery calcifications on temporal bone CT in children

    Energy Technology Data Exchange (ETDEWEB)

    Koch, Bernadette; Jones, Blaise [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Blackham, Aaron [University of Cincinnati College of Medicine, Cincinnati, OH (United States)

    2007-02-15

    Incidental internal carotid artery (ICA) calcifications are occasionally noted on CT images of the brain and temporal bone. In adults, incidental calcifications have been correlated with increased incidence of hypercholesterolemia, cardiac disease, diabetes and carotid stenosis. To determine the incidence of incidental calcifications of the carotid siphon on temporal bone CT in children. We retrospectively reviewed 24 months of consecutive temporal bone CT examinations in children aged 18 years and younger. CT examinations on 663 patients were reviewed and the presence or absence of ICA calcifications was ranked as absent, questionable or definitive. In patients in whom definitive calcifications were identified, hospital charts were reviewed for evidence of diabetes mellitus, hypercholesterolemia, hypertriglyceridemia, hyperlipidemia and chronic renal disease as potential causes of early atherosclerosis. Of the 663 patients, 25% had definitive calcifications within the wall of the ICA: 6% of children younger than 2 years and 28% of children 12-19 years of age. Incidentally noted ICA calcifications are a common finding on temporal bone CT in children, most likely a physiologic response to turbulent flow at natural bends in the artery rather than secondary to underlying disease predisposing to early atherosclerotic calcification. (orig.)

  2. Incidental internal carotid artery calcifications on temporal bone CT in children

    International Nuclear Information System (INIS)

    Koch, Bernadette; Jones, Blaise; Blackham, Aaron

    2007-01-01

    Incidental internal carotid artery (ICA) calcifications are occasionally noted on CT images of the brain and temporal bone. In adults, incidental calcifications have been correlated with increased incidence of hypercholesterolemia, cardiac disease, diabetes and carotid stenosis. To determine the incidence of incidental calcifications of the carotid siphon on temporal bone CT in children. We retrospectively reviewed 24 months of consecutive temporal bone CT examinations in children aged 18 years and younger. CT examinations on 663 patients were reviewed and the presence or absence of ICA calcifications was ranked as absent, questionable or definitive. In patients in whom definitive calcifications were identified, hospital charts were reviewed for evidence of diabetes mellitus, hypercholesterolemia, hypertriglyceridemia, hyperlipidemia and chronic renal disease as potential causes of early atherosclerosis. Of the 663 patients, 25% had definitive calcifications within the wall of the ICA: 6% of children younger than 2 years and 28% of children 12-19 years of age. Incidentally noted ICA calcifications are a common finding on temporal bone CT in children, most likely a physiologic response to turbulent flow at natural bends in the artery rather than secondary to underlying disease predisposing to early atherosclerotic calcification. (orig.)

  3. LCA of a condensing boiler according to EuP Directive

    International Nuclear Information System (INIS)

    Tremonti, M.; Breedvelt, L.; Padovan, G.; Bosio, S.; Corsini, M.

    2008-01-01

    In the light of the EuP Directive (2005/32/EC), producers of Energy using Product (EuP) are obliged to initiate eco design activities. Fourteen product groups are currently under study, one being the preparatory EC study Eco Boiler, and will result in a EuP Working Plan. The LCA of a condensing boiler, commissionated by an Italian SME in the Lombardy Region, has been conducted to support its environmental strategy and communication, to start implementing eco design activities and to anticipate implications to the EuP Directive. In line with the Eco Boiler study, no detailed LCA has been applied, instead a simplified LCA proves to be a strategic tool to support the company environmental objectives. Specifically, the condensing boiler (the option with the best environmental performance and the lowest life cycle costs for the final consumer) has been internally compared to other boilers, resulting in useful eco design recommendations

  4. LCA-LCCA of oil fired steam turbine power plant in Singapore

    International Nuclear Information System (INIS)

    Kannan, R.; Tso, C.P.; Osman, Ramli; Ho, H.K.

    2004-01-01

    A life cycle assessment (LCA) was conducted to quantify the non-renewable energy use and global warming potential in electricity generation from a typical oil fired steam turbine plant in Singapore. As the conventional LCA does not include any cost analysis, which is a major criterion in decision making, the cost of power generation is estimated using a life cycle cost analysis (LCCA) tool. It is estimated that the hidden processes consumed about 9% additional energy on top of the fuel embedded energy, while the hidden GHG emission is about 12%. A correlation is established to estimate the life cycle energy use and GHG emissions directly from the power plant net efficiency. The study methodology, results and the empirical relations are presented, together with a brief overview of the Singapore power sector. It also highlights the need for consideration of the reserves availability in the pricing mechanism and how such cost indices could be developed based on the LCA-LCCA

  5. LCA-LCCA of oil fired steam turbine power plant in Singapore

    International Nuclear Information System (INIS)

    Kannan, R.; Tso, C.P.; Osman, Ramli; Ho, H.K.

    2004-01-01

    A life cycle assessment (LCA) was conducted to quantify the non-renewable energy use and global warming potential in electricity generation from a typical oil fired steam turbine plant in Singapore. As the conventional LCA does not include any cost analysis, which is a major criterion in decision making, the cost of power generation is estimated using a life cycle cost analysis (LCCA) tool. It is estimated that the hidden processes consumed about 9% additional energy on top of the fuel embedded energy, while the hidden GHG emission is about 12%. A correlation is established to estimate the life cycle energy use and GHG emissions directly from the power plant net efficiency. The study methodology, results and the empirical relations are presented, together with a brief overview of the Singapore power sector. It also highlights the need for consideration of the reserves availability in the pricing mechanism and how such cost indices could be developed based on the LCA-LCCA. (Author)

  6. LCA of waste management systems: Development of tools for modeling and uncertainty analysis

    DEFF Research Database (Denmark)

    Clavreul, Julie

    Since the late 1990s, life cycle assessment (LCA) has been increasingly applied to waste management to quantify direct, indirect and avoided impacts from various treatment options. The construction of inventories for waste management systems differs from classical product-LCAs in that (1...... to be modelled rather than monitored as in classical LCA (e.g. landfilling or the application of processed waste on agricultural land). Therefore LCA-tools are needed which specifically address these issues and enable practitioners to model properly their systems. In this thesis several pieces of work...... in waste treatment technologies. These material transfer functions specify how substances in input flows are transferred to output flows and environmental compartments and include for example processes for anaerobic digestion or landfill gas generation. • Offering a flexible user interface where the user...

  7. Environmental assessment of solid waste landfilling technologies by means of LCA-modeling

    DEFF Research Database (Denmark)

    Manfredi, Simone; Christensen, Thomas Højlund

    2009-01-01

    By using life cycle assessment (LCA) modeling, this paper compares the environmental performance of six landfilling technologies (open dump, conventional landfill with flares, conventional landfill with energy recovery, standard bioreactor landfill, flushing bioreactor landfill and semi......-aerobic landfill) and assesses the influence of the active operations practiced on these performances. The environmental assessments have been performed by means of the LCA-based tool EASEWASTE, whereby the functional unit utilized for the LCA is “landfilling of 1 ton of wet household waste in a 10 m deep landfill...... that it is crucially important to ensure the highest collection efficiency of landfill gas and leachate since a poor capture compromises the overall environmental performance. Once gas and leachate are collected and treated, the potential impacts in the standard environmental categories and on spoiled groundwater...

  8. Systematic, efficient and consistent LCA calculations for chemical and biochemical processes

    DEFF Research Database (Denmark)

    Petchkaewkul, Kaesinee; Malakul, Pomthong; Gani, Rafiqul

    2016-01-01

    that allow a wider coverage of chemical and biochemical processes. Improvements of LCIA calculations and eco-efficiency evaluation are introduced. Also, a new model for photochemical ozone formation has been developed and implemented. Performance of LCSoft in terms of accuracy and reliability is compared......Life Cycle Assessment or LCA is a technique, which is applied for the study and evaluation of quantitative environmental impacts through the entire life cycle of products, processes or services in order to improve and/or evaluate the design of existing as well as new processes. The LCA factors can...... with another well-known LCA-software, SimaPro for a biochemical process – the production of bioethanol from cassava rhizome. The results show a very good match of new added impact categories. Also, the results from a new feature in LCSoft, which is eco-efficiency evaluation, are presented....

  9. Deliverable 4.1 Homogeneous LCA methodology agreed by NEPTUNE and INNOWATECH

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred; Hauschild, Michael Zwicky; Wenzel, Henrik

    2007-01-01

    In order to do a life cycle assessment (LCA) of a waste water treatment technique, a system to handle the mapped inventory data and a life cycle impact assessment (LCIA) method/model is needed. Besides NEPTUNE, another EU-funded project has the same methodology need namely INNOWATECH (contract No....... 036882) running in parallel with NEPTUNE but focusing on industrial waste water. With the aim of facilitating cooperation between the two projects a common LCA methodology framework has been worked out and is described in the following. This methodology work has been done as a joint effort between...... NEPTUNE WP4 and INNOWATECH WP4 represented by the WP4 lead partner IVL. The aim of the co-operation is to establish common methodologies and/or LCA models and/or tools in order to achieve a homogenous approach in INNOWATECH and NEPTUNE. Further, the aim is to facilitate possibilities of data exchange...

  10. The applicability of LCA to evaluate the key environmental challenges in food supply chains

    DEFF Research Database (Denmark)

    Aronsson, Anna K.S.; Landquist, Birgit; Esturo, Aintzane

    2014-01-01

    System analysis was performed to gain an overview of key environmental challenges and pinpoint hotspots causing environmental impacts in three European food supply chains. An overview was obtained based on a review on LCA studies for beef, dairy, orange juice and aquaculture food supply chains....... Similarities of the main environmental impacts were identified to rationalize and justify the selection of key performance indicators chosen for a simplified web based LCA tool developed within the EC funded project SENSE (FP7). Life Cycle Assessment methodology covered many of the key challenges identified...... but will not be sufficient to address all environmental impacts generated from the food supply chains. Especially for aquaculture impacts that are not taken into account with LCA are i.e. nutrient and organic matter releases, impacts associated with feed provision, diseases introduction, escapes, and changed usage...

  11. Cone Beam Computed Tomography Analysis of Incidental Maxillary Sinus Pathologies in North Indian Population

    Directory of Open Access Journals (Sweden)

    Sangeeta S Malik

    2017-01-01

    Full Text Available Introduction: Maxillary sinus can be visualized in both two-dimensional and three-dimensional images. Computed tomography (CT is considered the gold standard method for the examination of maxillary sinus. Cone beam computed tomography (CBCT addresses the limitation of CT and provides many dental advantages. It can provide valuable knowledge about the pathology with limited exposure and low cost compared with other imaging used for diagnostic purposes. Aims and Objectives: The aim of the study is to analyze the prevalence of pathological changes in maxillary sinus of asymptomatic cases using CBCT for diagnostic purposes. Materials and Methods: This retrospective study evaluated 231 patients for incidental maxillary sinus pathologies. Pathological findings were categorized as mucosal thickening, polypoid mucosal thickening, radiopacification, and no pathological findings. Evaluation of pathological findings was done using factors of age and gender. Results: The present study showed 86 cases with maxillary sinus pathology and 145 cases with no pathological findings. Patients with maxillary sinus pathology were mostly diagnosed with mucosal thickening on both sides. In right maxillary sinus, 45 cases (52.3% showed mucosal thickening, and on the left side 36 cases (41.9% were diagnosed with mucosal thickening. Among 86 cases reported, 20 right maxillary sinus (23.3% and 25 left maxillary sinus (29.1% showed no signs of pathology. Conclusion: The incidental maxillary sinus pathologies are highly prevalent in asymptomatic patients. Therefore, oral radiologists should be aware of these incidental findings which will help in early diagnosis and treatment of disease.

  12. Towards a meaningful assessment of marine ecological impacts in life cycle assessment (LCA).

    Science.gov (United States)

    Woods, John S; Veltman, Karin; Huijbregts, Mark A J; Verones, Francesca; Hertwich, Edgar G

    2016-01-01

    Human demands on marine resources and space are currently unprecedented and concerns are rising over observed declines in marine biodiversity. A quantitative understanding of the impact of industrial activities on the marine environment is thus essential. Life cycle assessment (LCA) is a widely applied method for quantifying the environmental impact of products and processes. LCA was originally developed to assess the impacts of land-based industries on mainly terrestrial and freshwater ecosystems. As such, impact indicators for major drivers of marine biodiversity loss are currently lacking. We review quantitative approaches for cause-effect assessment of seven major drivers of marine biodiversity loss: climate change, ocean acidification, eutrophication-induced hypoxia, seabed damage, overexploitation of biotic resources, invasive species and marine plastic debris. Our review shows that impact indicators can be developed for all identified drivers, albeit at different levels of coverage of cause-effect pathways and variable levels of uncertainty and spatial coverage. Modeling approaches to predict the spatial distribution and intensity of human-driven interventions in the marine environment are relatively well-established and can be employed to develop spatially-explicit LCA fate factors. Modeling approaches to quantify the effects of these interventions on marine biodiversity are less well-developed. We highlight specific research challenges to facilitate a coherent incorporation of marine biodiversity loss in LCA, thereby making LCA a more comprehensive and robust environmental impact assessment tool. Research challenges of particular importance include i) incorporation of the non-linear behavior of global circulation models (GCMs) within an LCA framework and ii) improving spatial differentiation, especially the representation of coastal regions in GCMs and ocean-carbon cycle models. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Life cycle assessment (LCA of lead-free solders from the environmental protection aspect

    Directory of Open Access Journals (Sweden)

    Mitovski Aleksandra M.

    2009-01-01

    Full Text Available Life-cycle assessment (LCA presents a relatively new approach, which allows comprehensive environmental consequences analysis of a product system over its entire life. This analysis is increasingly being used in the industry, as a tool for investigation of the influence of the product system on the environment, and serves as a protection and prevention tool in ecological management. This method is used to predict possible influences of a certain material to the environment through different development stages of the material. In LCA, the product systems are evaluated on a functionally equivalent basis, which, in this case, was 1000 cubic centimeters of an alloy. Two of the LCA phases, life-cycle inventory (LCA and life-cycle impact assessment (LCIA, are needed to calculate the environmental impacts. Methodology of LCIA applied in this analysis aligns every input and output influence into 16 different categories, divided in two subcategories. The life-cycle assessment reaserch review of the leadfree solders Sn-Cu, SAC (Sn-Ag-Cu, BSA (Bi-Sb-Ag and SABC (Sn-Ag-Bi-Cu respectively, is given in this paper, from the environmental protection aspect starting from production, through application process and finally, reclamation at the end-of-life, i.e. recycling. There are several opportunities for reducing the overall environmental and human health impacts of solder used in electronics manufacturing based on the results of the LCA, such as: using secondary metals reclaimed through post-industrial recycling; power consumption reducing by replacing older, less efficient reflow assembly equipment, or by optimizing the current equipment to perform at the elevated temperatures required for lead-free soldering, etc. The LCA analysis was done comparatively in relation to widely used Sn-Pb solder material. Additionally, the impact factors of material consumption, energy use, water and air reserves, human health and ecotoxicity have been ALSO considered including

  14. 78 FR 52135 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental To...

    Science.gov (United States)

    2013-08-22

    ...--Marine Mammal Density Estimates Density Species (animals/km \\2\\) Bottlenose dolphin \\1\\ 0.455 Atlantic... criteria and thresholds in a final rule on the unintentional taking of marine animals occurring incidental... analysis assumed the marine species populations were 100 percent small animals. The criterion with the...

  15. PestLCI - a model for estimating field emissions of pesticides in agricultural LCA

    DEFF Research Database (Denmark)

    Birkved, Morten; Hauschild, Michael Zwicky

    2006-01-01

    of a product or service is a specific element of LCA termed life cycle inventory (LCI). Estimation of chemical emissions in agricultural LCA is typically based on standard emission factors which at best are determined by a few physical-chemical substance properties and the use scenario of the chemical compound...... to the different environmental compartments. It estimates the fractions of the applied quantity which is emitted to the air, surface water, and groundwater compartment based on information which will normally be available to the model user about: type and time of application, crop species and development stage...... for other regions of the world. (c) 2006 Elsevier B.V. All rights reserved....

  16. Impact Assessment of Abiotic Resources in LCA: Quantitative Comparison of Selected Characterization Models

    DEFF Research Database (Denmark)

    Rørbech, Jakob Thaysen; Vadenbo, Carl; Hellweg, Stefanie

    2014-01-01

    Resources have received significant attention in recent years resulting in development of a wide range of resource depletion indicators within life cycle assessment (LCA). Understanding the differences in assessment principles used to derive these indicators and the effects on the impact assessment...... results is critical for indicator selection and interpretation of the results. Eleven resource depletion methods were evaluated quantitatively with respect to resource coverage, characterization factors (CF), impact contributions from individual resources, and total impact scores. We included 2247...... groups, according to method focus and modeling approach, to aid method selection within LCA....

  17. An Incidentally Detected Right Ventricular Pseudoaneurysm

    Directory of Open Access Journals (Sweden)

    Vamsi C. Gaddipati

    2017-01-01

    Full Text Available Ventricular pseudoaneurysm is an uncommon, potentially fatal complication that has been associated with myocardial infarction, cardiac surgery, chest trauma, and infectious processes. Diagnosis can be challenging, as cases are rare and slowly progressing and typically lack identifiable features on clinical presentation. As a result, advanced imaging techniques have become the hallmark of identification. Ahead, we describe a patient who presents with acute decompensated heart failure and was incidentally discovered to have a large right ventricular pseudoaneurysm that developed following previous traumatic anterior rib fracture.

  18. Impact of reading purpose on incidental word learning from context

    NARCIS (Netherlands)

    Swanborn, MSL; de Glopper, Kees

    Children read texts for various reasons. We examined how reading texts for different purposes affected amounts of incidental word learning. Grade 6 students were asked to read texts for fun, to learn about the topic of the text, and for text comprehension. Proportions of words learned incidentally

  19. Incidental Learning of Gender Agreement in L2

    Science.gov (United States)

    Denhovska, Nadiia; Serratrice, Ludovica

    2017-01-01

    Incidental learning of grammar has been an area of interest for many decades; nevertheless, existing research has primarily focused on artificial or semi-artificial languages. The present study examines the incidental acquisition of the grammar of a natural language by exposing adult speakers of an ungendered L1 (English) to the gender agreement…

  20. A tomato ER-type Ca2+-ATPase, LCA1, has a low thapsigargin-sensitivity and can transport manganese

    DEFF Research Database (Denmark)

    Johnson, Neil A.; Liu, F; Weeks, P. D.

    2008-01-01

    and directly via in vitro ATP hydrolysis. We found LCA1 to be approximately 300-fold less sensitive to thapsigargin than animal SERCAs, whereas ECA1 was thapsigargin-resistant. LCA1 showed typical pharmacological sensitivities to cyclopiazonic acid, vanadate, and eosin, consistent with it being a P...

  1. Extra-mammary findings in breast MRI

    Energy Technology Data Exchange (ETDEWEB)

    Rinaldi, Pierluigi; Costantini, M.; Belli, P.; Giuliani, M.; Bufi, E.; Fubelli, R.; Distefano, D.; Romani, M.; Bonomo, L. [Catholic University - Policlinic A. Gemelli, Department of Bio-Imaging and Radiological Sciences, Rome (Italy)

    2011-11-15

    Incidental extra-mammary findings in breast Magnetic Resonance Imaging (MRI) may be benign in nature, but may also represent a metastasis or another important lesion. We aimed to analyse the prevalence and clinical relevance of these unexpected findings. A retrospective review of 1535 breast MRIs was conducted. Only axial sequences were reassessed. Confirmation examinations were obtained in all cases. 285 patients had a confirmed incidental finding, which were located in the liver (51.9%), lung (11.2%), bone (7%), mediastinal lymph nodes (4.2%) or consisted of pleural/pericardial effusion (15.4%). 20.4% of incidental findings were confirmed to be malignant. Positive predictive value for MRI to detect a metastatic lesion was high if located within the bone (89%), lymph nodes (83%) and lung (59%), while it was low if located within the liver (9%) or if it consisted of pleural/pericardial effusion (6%). The axial enhanced sequence showed superior sensitivity to unenhanced images in detecting metastatic lesions, especially if only smaller ({<=}10 mm.) lesions were considered. The prevalence of metastatic incidental extra-mammary findings is not negligible. Particular attention should be to incidental findings located within the lung, bone and mediastinal lymph nodes. (orig.)

  2. Incidental pineal cysts in children who undergo 3-T MRI

    International Nuclear Information System (INIS)

    Whitehead, Matthew T.; Oh, Christopher C.; Choudhri, Asim F.

    2013-01-01

    Pineal cysts, both simple and complex, are commonly encountered in children. More cysts are being detected with MR technology; however, nearly all pineal cysts are benign and require no follow-up. To discover the prevalence of pineal cysts in children at our institution who have undergone high-resolution 3-T MRI. We retrospectively reviewed 100 consecutive 3-T brain MRIs in children ages 1 month to 17 years (mean 6.8 ± 5.1 years). We evaluated 3-D volumetric T1-W imaging, axial T2-W imaging, axial T2-W FLAIR (fluid attenuated inversion recovery) and coronal STIR (short tau inversion recovery) sequences. Pineal parenchymal and cyst volumes were measured in three planes. Cysts were analyzed for the presence and degree of complexity. Pineal cysts were present in 57% of children, with a mean maximum linear dimension of 4.2 mm (range 1.5-16 mm). Of these cysts, 24.6% showed thin septations or fluid levels reflecting complexity. None of the cysts demonstrated complete T2/FLAIR signal suppression. No cyst wall thickening or nodularity was present. There was no significant difference between the ages of children with and without cysts. Cysts were more commonly encountered in girls than boys (67% vs. 52%; P = 0.043). There was a slight trend toward increasing pineal gland volume with age. Pineal cysts are often present in children and can be incidentally detected by 3-T MRI. Characteristic-appearing pineal cysts in children are benign, incidental findings, for which follow-up is not required if there are no referable symptoms or excessive size. (orig.)

  3. An innovative implementation of LCA within the EIA procedure: Lessons learned from two Wastewater Treatment Plant case studies

    Energy Technology Data Exchange (ETDEWEB)

    Larrey-Lassalle, Pyrène, E-mail: pyrene.larrey-lassalle@irstea.fr [Irstea, UMR ITAP, ELSA Research Group & ELSA-PACT Industrial Chair for Environmental and Social Sustainability Assessment, 361 rue Jean François Breton, F-34196 Montpellier (France); LGEI, Ecole des mines d' Alès, 6 avenue de Clavières, 30319 Alès Cedex (France); Catel, Laureline; Roux, Philippe; Rosenbaum, Ralph K. [Irstea, UMR ITAP, ELSA Research Group & ELSA-PACT Industrial Chair for Environmental and Social Sustainability Assessment, 361 rue Jean François Breton, F-34196 Montpellier (France); Lopez-Ferber, Miguel; Junqua, Guillaume [LGEI, Ecole des mines d' Alès, 6 avenue de Clavières, 30319 Alès Cedex (France); Loiseau, Eléonore [Irstea, UMR ITAP, ELSA Research Group & ELSA-PACT Industrial Chair for Environmental and Social Sustainability Assessment, 361 rue Jean François Breton, F-34196 Montpellier (France)

    2017-03-15

    Life Cycle Assessment (LCA) has been identified in the literature as a promising tool to increase the performance of environmental assessments at different steps in the Environmental Impact Assessment (EIA) procedure. However, few publications have proposed a methodology for an extensive integration, and none have compared the results with existing EIA conclusions without LCA. This paper proposes a comprehensive operational methodology for implementing an LCA within an EIA. Based on a literature review, we identified four EIA steps that could theoretically benefit from LCA implementation, i.e., (a) the environmental comparison of alternatives, (b) the identification of key impacts, (c) the impact assessment, and (d) the impact of mitigation measures. For each of these steps, an LCA was implemented with specific goal and scope definitions that resulted in a specific set of indicators. This approach has been implemented in two contrasting Wastewater Treatment Plant (WWTP) projects and compared to existing EIA studies. The results showed that the two procedures, i.e., EIAs with or without inputs from LCA, led to different conclusions. The environmental assessments of alternatives and mitigation measures were not carried out in the original studies and showed that other less polluting technologies could have been chosen. Regarding the scoping step, the selected environmental concerns were essentially different. Global impacts such as climate change or natural resource depletion were not taken into account in the original EIA studies. Impacts other than those occurring on the project site (off-site impacts) were not assessed, either. All these impacts can be significant compared to those initially considered. On the other hand, unlike current LCA applications, EIAs usually address natural and technological risks and neighbourhood disturbances such as noises or odours, which are very important for the public acceptability of projects. Regarding the impact assessment

  4. An innovative implementation of LCA within the EIA procedure: Lessons learned from two Wastewater Treatment Plant case studies

    International Nuclear Information System (INIS)

    Larrey-Lassalle, Pyrène; Catel, Laureline; Roux, Philippe; Rosenbaum, Ralph K.; Lopez-Ferber, Miguel; Junqua, Guillaume; Loiseau, Eléonore

    2017-01-01

    Life Cycle Assessment (LCA) has been identified in the literature as a promising tool to increase the performance of environmental assessments at different steps in the Environmental Impact Assessment (EIA) procedure. However, few publications have proposed a methodology for an extensive integration, and none have compared the results with existing EIA conclusions without LCA. This paper proposes a comprehensive operational methodology for implementing an LCA within an EIA. Based on a literature review, we identified four EIA steps that could theoretically benefit from LCA implementation, i.e., (a) the environmental comparison of alternatives, (b) the identification of key impacts, (c) the impact assessment, and (d) the impact of mitigation measures. For each of these steps, an LCA was implemented with specific goal and scope definitions that resulted in a specific set of indicators. This approach has been implemented in two contrasting Wastewater Treatment Plant (WWTP) projects and compared to existing EIA studies. The results showed that the two procedures, i.e., EIAs with or without inputs from LCA, led to different conclusions. The environmental assessments of alternatives and mitigation measures were not carried out in the original studies and showed that other less polluting technologies could have been chosen. Regarding the scoping step, the selected environmental concerns were essentially different. Global impacts such as climate change or natural resource depletion were not taken into account in the original EIA studies. Impacts other than those occurring on the project site (off-site impacts) were not assessed, either. All these impacts can be significant compared to those initially considered. On the other hand, unlike current LCA applications, EIAs usually address natural and technological risks and neighbourhood disturbances such as noises or odours, which are very important for the public acceptability of projects. Regarding the impact assessment

  5. Imbalance of incidental encoding across tasks: An explanation for non-memory-related hippocampal activations?

    OpenAIRE

    Reas, Emilie T.; Brewer, James B.

    2013-01-01

    Functional neuroimaging studies have increasingly noted hippocampal activation associated with a variety of cognitive functions such as decision-making, attention, perception, incidental learning, prediction and working memory, which have little apparent relation to declarative memory. Such findings might be difficult to reconcile with classical hippocampal lesion studies that show remarkable sparing of cognitive functions outside the realm of declarative memory. Even the oft-reported hippoca...

  6. 76 FR 41463 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a...

    Science.gov (United States)

    2011-07-14

    ... requirements, many marine animals may need to remain in areas where they are exposed to chronic stimuli... Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to a Marine... Atmospheric Administration (NOAA), National Marine Fisheries Service (NMFS). ACTION: Notice; proposed...

  7. Modelling sensitivity and uncertainty in a LCA model for waste management systems - EASETECH

    DEFF Research Database (Denmark)

    Damgaard, Anders; Clavreul, Julie; Baumeister, Hubert

    2013-01-01

    In the new model, EASETECH, developed for LCA modelling of waste management systems, a general approach for sensitivity and uncertainty assessment for waste management studies has been implemented. First general contribution analysis is done through a regular interpretation of inventory and impact...

  8. Assessing Resource Intensity and Renewability of Cellulosic Ethanol Technologies using Eco-LCA

    Science.gov (United States)

    Recognizing the contributions of natural resources and the lack of their comprehensive accounting in life cycle assessment (LCA) of cellulosic ethanol, an in-depth analysis of the contribution of natural resources in the life cycle of cellulosic ethanol derived from five differen...

  9. Valg af afværge med inddragelse af livscyklusvurdering (LCA)

    DEFF Research Database (Denmark)

    Lemming, Gitte; Chambon, Julie Claire Claudia; Binning, Philip John

    2012-01-01

    Livscyklusvurdering (LCA) er anvendt til at sammenligne miljøeffekterne ved forskellige alternativer til at rense op på to forskellige TCE-forurenede grunde. De sammenlignede afværgealternativer for Lokalitet 1 er (i) in situ stimuleret reduktiv deklorering, (ii) in situ termisk desorption og (iii...

  10. The Use of Facade Mockups in in LCA Based Architectural Design

    DEFF Research Database (Denmark)

    Naboni, Emanuele

    2017-01-01

    Life Cycle Assessment is increasingly becoming important in façade architectural design. The presented research aims to describe an LCA architectural design approach based on the use of a Façade Mockup. The approach is applied and tested for the design Telecom Sustainable Campus’ façade, in Rome...

  11. LCA Study for Pilot Scale Production of Cellulose Nano Crystals (CNC) from Wood Pulp

    Science.gov (United States)

    Hongmei Gu; Richard Reiner; Richard Bergman; Alan Rudie

    2015-01-01

    Interest in cellulose nanocrystals (CNC)/cellulose nanofibrils (CNF) made from woody biomass has been growing rapidly with close attention from pulp and paper industry, governments, universities, and research institutes. Many new products development with CNCs have been studied intensively. However, little life-cycle analysis (LCA) has been conducted for the...

  12. Environmental impact assessment of CCS chains – Lessons learned and limitations from LCA literature

    NARCIS (Netherlands)

    Corsten, M.A.M.; Ramirez, C.A.; Shen, L.; Koornneef, A.; Faaij, A.P.C.

    2013-01-01

    This study performs an assessment of existing LCA literature to obtain insights into potential environmental impacts over the complete life cycle of fossil fuel fired power plants with CCS. CCS results in a net reduction of the GWP of power plants through their life cycle in the order of 65–84%

  13. Sustainable Design with Respect to LCA Using Parametric Design and BIM Tools

    DEFF Research Database (Denmark)

    Tsikos, Marios; Negendahl, Kristoffer

    minimize their design’s environmental impacts. To achieve this, this study evaluated the potential of integrating LCA into BIM, developed and proposed an Integrated Dynamic Model using Revit, Dynamo and Excel. The Integrated Dynamic model was used in case studies the results of which were compared...

  14. LCA to choose among alternative design solutions: The case study of a new Italian incineration line

    International Nuclear Information System (INIS)

    Scipioni, A.; Mazzi, A.; Niero, M.; Boatto, T.

    2009-01-01

    At international level LCA is being increasingly used to objectively evaluate the performances of different Municipal Solid Waste (MSW) management solutions. One of the more important waste management options concerns MSW incineration. LCA is usually applied to existing incineration plants. In this study LCA methodology was applied to a new Italian incineration line, to facilitate the prediction, during the design phase, of its potential environmental impacts in terms of damage to human health, ecosystem quality and consumption of resources. The aim of the study was to analyse three different design alternatives: an incineration system with dry flue gas cleaning (without- and with-energy recovery) and one with wet flue gas cleaning. The last two technological solutions both incorporating facilities for energy recovery were compared. From the results of the study, the system with energy recovery and dry flue gas cleaning revealed lower environmental impacts in relation to the ecosystem quality. As LCA results are greatly affected by uncertainties of different types, the second part of the work provides for an uncertainty analysis aimed at detecting the extent output data from life cycle analysis are influenced by uncertainty of input data, and employs both qualitative (pedigree matrix) and quantitative methods (Monte Carlo analysis).

  15. LCA as a Tool for Assessing Product and Process Oriented Eco-Innovations Undertaken by Enterprises

    Directory of Open Access Journals (Sweden)

    Rybaczewska-Błażejowska Magdalena

    2017-09-01

    Full Text Available This paper examines the application of life cycle assessment (LCA as an approach to foster the product and process oriented eco- innovation of enterprises, using the fruit and vegetable processing plant as an example. LCA, which is traditionally used to assess the impacts of a single product system on the environment, was applied in the enterprise context. This was made possible by forming an indicator describing the environmental profile of an enterprise, which is calculated by the sum of the multiplication of the environmental impact assessment (LCIA results for individual unit processes within a particular impact category and their weights reflecting the structure of production in an enterprise. In order to distinguish and indicate the direction in which an enterprise should undertake its eco-innovative actions (implementing eco-innovations within the product or production process the LCIA results are presented individually for products and production processes. The research was conducted in full compliance with the LCA methodology. LCA proved that the analysed enterprise has the largest negative impacts on the environment in the following impact categories: marine eco-toxicity, freshwater eco-toxicity, freshwater eutrophication, human toxicity and natural land transformation. They result primarily from the consumption of thermal and electric energy in the production processes. Therefore, to improve energy efficiency, the enterprise should take eco-innovative actions in the processes applied.

  16. Generic model for calculating carbon footprint of milk using four different LCA modelling approaches

    DEFF Research Database (Denmark)

    Dalgaard, Randi; Schmidt, Jannick Højrup; Flysjö, Anna

    2014-01-01

    The aim of the study is to develop a tool, which can be used for calculation of carbon footprint (using a life cycle assessment (LCA) approach) of milk both at a farm level and at a national level. The functional unit is ‘1 kg energy corrected milk (ECM) at farm gate’ and the applied methodology...

  17. Toward a computational structure for life cycle sustainability analysis: unifying LCA and LCC

    NARCIS (Netherlands)

    Heijungs, R.; Settanni, E.; Guinée, J.

    2013-01-01

    Purpose: A widely used theory of the computational structure of life cycle assessment (LCA) has been available for more than a decade. The case of environmental life cycle cost (LCC) is still less clear: even the recent Code of Practice does not specify any formula to use. Methods: This paper does

  18. Milestone 4.1 ∙ First draft on complemented LCA methodology

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred; Olsen, Stig Irving; Hauschild, Michael Zwicky

    As described in deliverable 4.1, D4.1 (Larsen et al. 2007) NEPTUNE is using two main types of life cycle impact assessment (LCIA) methodologies when doing LCA studies on the waste water treatment technologies included. The basic methodology is the well known existing EDIP97 methodology (Wenzel et...

  19. The Progress of LCA Center Denmark After Almost Two Years of Service

    DEFF Research Database (Denmark)

    Frydendal, Jeppe; Hauschild, Michael Zwicky

    2004-01-01

    . promote the use of Life Cycle Assessment and other product-oriented environmental tools in companies, 2. support companies and other in using environmental assessment of products and services, 3. ensure that the effort in the LCA area is based on a solid and scientific basis, and 4. maintain the well...

  20. Open-loop recycling: A LCA case study of PET bottle-to-fibre-recycling

    NARCIS (Netherlands)

    Shen, L.; Worrell, E.; Patel, M.K.

    2010-01-01

    This study assesses the environmental impact of polyethylene terephthalate (PET) bottle-to-fibre recycling using the methodology of life-cycle assessment (LCA). Four recycling cases, including mechanical recycling, semi-mechanical recycling, back-to-oligomer recycling and back-to-monomer recycling

  1. GLOBOX : A spatially differentiated global fate, intake and effect model for toxicity assessment in LCA

    NARCIS (Netherlands)

    Wegener Sleeswijk, Anneke; Heijungs, Reinout

    GLOBOX is a model for the calculation of spatially differentiated LCA toxicity characterisation factors on a global scale. It can also be used for human and environmental risk assessment. The GLOBOX model contains equations for the calculation of fate, intake and effect factors, and equations for

  2. Comparison of environmental impact and energy efficiency of desalination processes by LCA

    NARCIS (Netherlands)

    Tarnacki, K.M.; Melin, T.; Jansen, A.E.; Medevoort, J. van

    2011-01-01

    In this study two desalination technologies have been compared by means of LCA with the focus on energy supply with a variety of scenarios based on different assumptions. The studied technologies are reverse osmosis and the newly developed technology Memstill where electrical energy demand is

  3. Cardiac pathologies incidentally detected with non-gated chest CT; Inzidentelle Pathologien des Herzens im Thorax-CT

    Energy Technology Data Exchange (ETDEWEB)

    Scherer, Axel; Kroepil, P.; Lanzman, R.S.; Moedder, U. [Inst. fuer Radiologie, Universitaetsklinikum Duesseldorf, Heinrich-Heine-Univ. (Germany); Choy, G.; Abbara, S. [Cardiovascular Imaging Section, Massachusetts General Hospital, Harvard Medical School (United States)

    2009-12-15

    Cardiac imaging using electrocardiogram-gated multi-detector computed tomography (MDCT) permits noninvasive diagnosis of congenital and acquired cardiac pathologies and has thus become increasingly important in the last years. Several studies investigated the incidence and relevance of incidental extracardiac structures within the lungs, mediastinum, chest wall, and abdomen with gated coronary CT. This resulted in the general acceptance of the review of extracardiac structures as a routine component of coronary CT interpretation. On the other hand radiologists tend to neglect pericardial and cardiac pathologies in non-gated chest CT, which is primarily performed for the evaluation of the respiratory system or for tumor staging. Since the introduction of multi-detector spiral CT technology, the incidental detection of cardiac and pericardial findings has become possible using non-gated chest CT. This article reviews the imaging appearances and differential diagnostic considerations of incidental cardiac entities that may be encountered in non-gated chest CT. (orig.)

  4. Life cycle thinking in impact assessment—Current practice and LCA gains

    International Nuclear Information System (INIS)

    Bidstrup, Morten

    2015-01-01

    It has been advocated that life cycle thinking (LCT) should be applied in impact assessment (IA) to a greater extent, since some development proposals pose a risk of significant impacts throughout the interconnected activities of product systems. Multiple authors have proposed the usage of life cycle assessment (LCA) for such analytical advancement, but little to no research on this tool application has been founded in IA practice so far. The aim of this article is to elaborate further on the gains assigned to application of LCA. The research builds on a review of 85 Danish IA reports, which were analysed for analytical appropriateness and application of LCT. Through a focus on the non-technical summary, the conclusion and the use of specific search words, passages containing LCT were searched for in each IA report. These passages were then analysed with a generic framework. The results reveal that LCT is appropriate for most of the IAs, but that LCA is rarely applied to provide such a perspective. Without LCA, the IAs show mixed performance in regard to LCT. Most IAs do consider the product provision of development proposals, but they rarely relate impacts to this function explicitly. Many IAs do consider downstream impacts, but assessments of upstream, distant impacts are generally absent. It is concluded that multiple analytical gains can be attributed to greater application of LCA in IA practice, though some level of LCT already exists. - Highlights: • Life cycle thinking is appropriate across the types and topics of impact assessment. • Yet, life cycle assessment is rarely used for adding such perspective. • Impact assessment practice does apply some degree of life cycle thinking. • However, application of life cycle assessment could bring analytical gains

  5. Life cycle thinking in impact assessment—Current practice and LCA gains

    Energy Technology Data Exchange (ETDEWEB)

    Bidstrup, Morten, E-mail: Bidstrup@plan.aau.dk

    2015-09-15

    It has been advocated that life cycle thinking (LCT) should be applied in impact assessment (IA) to a greater extent, since some development proposals pose a risk of significant impacts throughout the interconnected activities of product systems. Multiple authors have proposed the usage of life cycle assessment (LCA) for such analytical advancement, but little to no research on this tool application has been founded in IA practice so far. The aim of this article is to elaborate further on the gains assigned to application of LCA. The research builds on a review of 85 Danish IA reports, which were analysed for analytical appropriateness and application of LCT. Through a focus on the non-technical summary, the conclusion and the use of specific search words, passages containing LCT were searched for in each IA report. These passages were then analysed with a generic framework. The results reveal that LCT is appropriate for most of the IAs, but that LCA is rarely applied to provide such a perspective. Without LCA, the IAs show mixed performance in regard to LCT. Most IAs do consider the product provision of development proposals, but they rarely relate impacts to this function explicitly. Many IAs do consider downstream impacts, but assessments of upstream, distant impacts are generally absent. It is concluded that multiple analytical gains can be attributed to greater application of LCA in IA practice, though some level of LCT already exists. - Highlights: • Life cycle thinking is appropriate across the types and topics of impact assessment. • Yet, life cycle assessment is rarely used for adding such perspective. • Impact assessment practice does apply some degree of life cycle thinking. • However, application of life cycle assessment could bring analytical gains.

  6. Bridging the gap between LCA, LCC and CBA as sustainability assessment tools

    Energy Technology Data Exchange (ETDEWEB)

    Hoogmartens, Rob, E-mail: rob.hoogmartens@uhasselt.be [Hasselt University, Faculty of Business Economics, Centre for Environmental Sciences, Agoralaan, Building D, 3590 Diepenbeek (Belgium); Van Passel, Steven, E-mail: steven.vanpassel@uhasselt.be [Hasselt University, Faculty of Business Economics, Centre for Environmental Sciences, Agoralaan, Building D, 3590 Diepenbeek (Belgium); Van Acker, Karel, E-mail: karel.vanacker@lrd.kuleuven.be [Katholieke Universiteit Leuven, Department of Metallurgy and Materials Engineering, Kasteelpark Arenberg 44, 3001 Leuven (Belgium); Dubois, Maarten, E-mail: maarten.dubois@kuleuven.be [Katholieke Universiteit Leuven, Policy Research Centre for Sustainable Materials, Kasteelpark Arenberg 44, 3001 Leuven (Belgium)

    2014-09-15

    Increasing interest in sustainability has led to the development of sustainability assessment tools such as Life Cycle Analysis (LCA), Life Cycle Costing (LCC) and Cost–Benefit Analysis (CBA). Due to methodological disparity of these three tools, conflicting assessment results generate confusion for many policy and business decisions. In order to interpret and integrate assessment results, the paper provides a framework that clarifies the connections and coherence between the included assessment methodologies. Building on this framework, the paper further focuses on key aspects to adapt any of the methodologies to full sustainability assessments. Aspects dealt with in the review are for example the reported metrics, the scope, data requirements, discounting, product- or project-related and approaches with respect to scarcity and labor requirements. In addition to these key aspects, the review shows that important connections exist: (i) the three tools can cope with social inequality, (ii) processes such as valuation techniques for LCC and CBA are common, (iii) Environmental Impact Assessment (EIA) is used as input in both LCA and CBA and (iv) LCA can be used in parallel with LCC. Furthermore, the most integrated sustainability approach combines elements of LCA and LCC to achieve the Life Cycle Sustainability Assessment (LCSA). The key aspects and the connections referred to in the review are illustrated with a case study on the treatment of end-of-life automotive glass. - Highlights: • Proliferation of assessment tools creates ambiguity and confusion. • The developed assessment framework clarifies connections between assessment tools. • Broadening LCA, key aspects are metric and data requirements. • Broadening LCC, key aspects are scope, time frame and discounting. • Broadening CBA, focus point, timespan, references, labor and scarcity are key.

  7. Bridging the gap between LCA, LCC and CBA as sustainability assessment tools

    International Nuclear Information System (INIS)

    Hoogmartens, Rob; Van Passel, Steven; Van Acker, Karel; Dubois, Maarten

    2014-01-01

    Increasing interest in sustainability has led to the development of sustainability assessment tools such as Life Cycle Analysis (LCA), Life Cycle Costing (LCC) and Cost–Benefit Analysis (CBA). Due to methodological disparity of these three tools, conflicting assessment results generate confusion for many policy and business decisions. In order to interpret and integrate assessment results, the paper provides a framework that clarifies the connections and coherence between the included assessment methodologies. Building on this framework, the paper further focuses on key aspects to adapt any of the methodologies to full sustainability assessments. Aspects dealt with in the review are for example the reported metrics, the scope, data requirements, discounting, product- or project-related and approaches with respect to scarcity and labor requirements. In addition to these key aspects, the review shows that important connections exist: (i) the three tools can cope with social inequality, (ii) processes such as valuation techniques for LCC and CBA are common, (iii) Environmental Impact Assessment (EIA) is used as input in both LCA and CBA and (iv) LCA can be used in parallel with LCC. Furthermore, the most integrated sustainability approach combines elements of LCA and LCC to achieve the Life Cycle Sustainability Assessment (LCSA). The key aspects and the connections referred to in the review are illustrated with a case study on the treatment of end-of-life automotive glass. - Highlights: • Proliferation of assessment tools creates ambiguity and confusion. • The developed assessment framework clarifies connections between assessment tools. • Broadening LCA, key aspects are metric and data requirements. • Broadening LCC, key aspects are scope, time frame and discounting. • Broadening CBA, focus point, timespan, references, labor and scarcity are key

  8. 75 FR 77617 - Taking of Marine Mammals Incidental to Specified Activities; Construction of the East Span of the...

    Science.gov (United States)

    2010-12-13

    ... functions, such as orientation, communication, finding prey, and avoiding predators, marine mammals that... Marine Mammals Incidental to Specified Activities; Construction of the East Span of the San Francisco... California. Pursuant to the Marine Mammal Protection Act (MMPA), NMFS is requesting comments on its proposal...

  9. 75 FR 54599 - Takes of Marine Mammals Incidental to Specified Activities; Construction of the Knik Arm Crossing...

    Science.gov (United States)

    2010-09-08

    ... with the Department of Transportation Federal Highways Administration (FHWA), for authorization to take... authorization is provided to the public for review. Authorization for incidental takings may be granted if NMFS finds that the taking will have a negligible impact on the species or stock(s), will not have an...

  10. Incidental diagnosis of pregnancy on bone and gallium scintigraphy

    International Nuclear Information System (INIS)

    Palestro, C.J.; Malat, J.; Collica, C.J.; Richman, A.H.

    1986-01-01

    Bone and gallium scintigraphy were performed as part of the diagnostic workup of a 21-yr-old woman who presented at our institution with a history of progressively worsening low back pain over a 1-wk period of time. The angiographic phase of the bone scan demonstrated a well-defined radionuclide blush within the pelvis just cephalad to the urinary bladder with persistent hyperemia noted in the blood-pool image. We attribute these findings to a uterine blush secondary to the pronounced uterine muscular hyperplasia, hyperemia, and edema that accompany pregnancy. Gallium scintigraphy demonstrated intense bilateral breast accumulation of the imaging agent in a typical doughnut pattern which is commonly found in the prelactating and lactating breast. Also demonstrated was apparent gallium accumulation in the placenta. This case is presented to emphasize the radionuclide findings that occur during pregnancy, particularly the incidental finding of radionuclide blush during the angiographic phase of a radionuclide scintigraphy which should alert the nuclear physician to the possibility of pregnancy in a woman of childbearing age

  11. Integrating LCA and Risk Assessment for Decision Support

    DEFF Research Database (Denmark)

    Dong, Yan; Miraglia, Simona; Manzo, Stefano

    The study aims at developing a methodology using decision analysis theory and tools to find the optimal policy (or design) of the studied system, to ensure both sustainability and meanwhile manage risks.......The study aims at developing a methodology using decision analysis theory and tools to find the optimal policy (or design) of the studied system, to ensure both sustainability and meanwhile manage risks....

  12. Incidental and intentional learning of verbal episodic material differentially modifies functional brain networks.

    Directory of Open Access Journals (Sweden)

    Marie-Therese Kuhnert

    Full Text Available Learning- and memory-related processes are thought to result from dynamic interactions in large-scale brain networks that include lateral and mesial structures of the temporal lobes. We investigate the impact of incidental and intentional learning of verbal episodic material on functional brain networks that we derive from scalp-EEG recorded continuously from 33 subjects during a neuropsychological test schedule. Analyzing the networks' global statistical properties we observe that intentional but not incidental learning leads to a significantly increased clustering coefficient, and the average shortest path length remains unaffected. Moreover, network modifications correlate with subsequent recall performance: the more pronounced the modifications of the clustering coefficient, the higher the recall performance. Our findings provide novel insights into the relationship between topological aspects of functional brain networks and higher cognitive functions.

  13. Incidental bony pathology when reporting trauma orthopantomograms

    International Nuclear Information System (INIS)

    Macanovic, M.; Gangidi, S.; Porter, G.; Brown, S.; Courtney, D.; Porter, J.

    2010-01-01

    Radiologists frequently report orthopantomograms (OPTs) and other views of the mandible, most often in patients who have suffered facial trauma. These examinations may reveal incidental pathology. It is important that radiologists are aware of the radiological appearances and the clinical significance of these lesions. In this review we will present examples of the more common odontogenic lesions including: radicular cyst, odontogenic keratocyst, dentigerous cyst, ameloblastoma, and also examples of non-odontogenic pathology: bisphosphonate-related osteonecrosis of the jaw (BRONJ) and chronic osteomyelitis. Although some of the lesions will require computed tomography (CT) or magnetic resonance imaging (MRI) for further lesion characterization and evaluation of the surrounding tissues, we are going to focus on the plain film appearances. We will also briefly discuss the pathogenesis, epidemiology, and treatment of these lesions.

  14. Incidental bony pathology when reporting trauma orthopantomograms

    Energy Technology Data Exchange (ETDEWEB)

    Macanovic, M., E-mail: mladenmaca@gmail.co [Derriford Hospital NHS Trust, Plymouth (United Kingdom); Gangidi, S.; Porter, G.; Brown, S.; Courtney, D. [Derriford Hospital NHS Trust, Plymouth (United Kingdom); Porter, J. [Community Dental Service, Plymouth Primary Care Trust, Plymouth, Devon (United Kingdom)

    2010-10-15

    Radiologists frequently report orthopantomograms (OPTs) and other views of the mandible, most often in patients who have suffered facial trauma. These examinations may reveal incidental pathology. It is important that radiologists are aware of the radiological appearances and the clinical significance of these lesions. In this review we will present examples of the more common odontogenic lesions including: radicular cyst, odontogenic keratocyst, dentigerous cyst, ameloblastoma, and also examples of non-odontogenic pathology: bisphosphonate-related osteonecrosis of the jaw (BRONJ) and chronic osteomyelitis. Although some of the lesions will require computed tomography (CT) or magnetic resonance imaging (MRI) for further lesion characterization and evaluation of the surrounding tissues, we are going to focus on the plain film appearances. We will also briefly discuss the pathogenesis, epidemiology, and treatment of these lesions.

  15. Renal cell carcinoma: incidental detection and pathological staging.

    Science.gov (United States)

    Siow, W Y; Yip, S K; Ng, L G; Tan, P H; Cheng, W S; Foo, K T

    2000-10-01

    In developed countries, there has been increased incidental detection of renal cell carcinoma (RCC). The incidence, pathological stage and survival of incidentally detected carcinoma in a developing country in Asia where, from 1990 to 1998, 165 renal cell carcinomas were identified. The clinical presentation, diagnostic-imaging modality employed, pathological staging and patient survival was reviewed. Incidental renal cancers included those that were diagnosed through health screening or detected incidentally through imaging studies for other conditions. The survival between these incidentally detected lesions and their symptomatic counterparts (suspected group) was compared. Sixty-four patients (39%) had their tumours detected incidentally, including 39 who were entirely asymptomatic and 25 who presented with non-specific symptoms, not initially suggestive of RCC. For the entire group, computed tomography provided the definitive diagnosis in 81% of cases. The incidental detection group had significantly smaller size of tumour (5.9 cm c.f. 7.6 cm), lower stage and lower histological grading. In particular, 78% of patients with incidental RCC had stage I or II diseases (TNM stage classification), compared with 57% of patients with suspected tumour (p c.f. 66% at last follow up; p < 0.05; log-rank test) over a mean follow up period of 33 months (range 1-91). Regression analysis showed that stage of disease was the only independent variable predictive of clinical outcome. In conclusion, that significant numbers of RCC were detected incidentally. These tumours were of a lower clinical pathological stage and had a better prognosis.

  16. Imbalance of incidental encoding across tasks: an explanation for non-memory-related hippocampal activations?

    Science.gov (United States)

    Reas, Emilie T; Brewer, James B

    2013-11-01

    Functional neuroimaging studies have increasingly noted hippocampal activation associated with a variety of cognitive functions--such as decision making, attention, perception, incidental learning, prediction, and working memory--that have little apparent relation to declarative memory. Such findings might be difficult to reconcile with classical hippocampal lesion studies that show remarkable sparing of cognitive functions outside the realm of declarative memory. Even the oft-reported hippocampal activations during confident episodic retrieval are not entirely congruent with evidence that hippocampal lesions reliably impair encoding but inconsistently affect retrieval. Here we explore the conditions under which the hippocampus responds during episodic recall and recognition. Our findings suggest that anterior hippocampal activity may be related to the imbalance of incidental encoding across tasks and conditions rather than due to retrieval per se. Incidental encoding and hippocampal activity may be reduced during conditions where retrieval requires greater attentional engagement. During retrieval, anterior hippocampal activity decreases with increasing search duration and retrieval effort, and this deactivation corresponds with a coincident impaired encoding of the external environment (Israel, Seibert, Black, & Brewer, 2010; Reas & Brewer, 2013; Reas, Gimbel, Hales, & Brewer, 2011). In light of this emerging evidence, we discuss the proposal that some hippocampal activity observed during memory retrieval, or other non-memory conditions, may in fact be attributable to concomitant encoding activity that is regulated by the attentional demands of the principal task. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  17. Microcarcinomas papilares de tiroides no incidentales Non-incidental papillary microcarcinomas of the thyroid

    Directory of Open Access Journals (Sweden)

    Marcelo Monteros Alvi

    2008-04-01

    Full Text Available El significado clínico de los microcarcinomas papilares de tiroides sigue siendo controvertido. La alta prevalencia en autopsias e incidental en tiroidectomías por patología benigna indican un comportamiento clínico indolente. Sin embargo, algunos desarrollan metástasis ganglionares y recurrencia local. Nuestro objetivo fue determinar características clínicas y patológicas de microcarcinonas papilares de tiroides no incidentales (MPT-NI. Se analizaron 18 pacientes con diagnóstico de microcarcinomas (tumor The clinical significance of papillary microcarcinoma of the thyroid gland keeps being controversial. Its high prevalence in autopsies and as incidental findings in thyroidectomy specimens for benign pathology indicate an indolent clinical behavior. Nevertheless some of the microcarcinomas develop lymph node metastasis and local recurrence. To determine the clinical and pathological characteristics of non-incidental papillary microcarcinomas of the thyroid (PTM -NI. 18 patients with diagnosis of non-incidental papillary microcarcinoma (tumor < 1cm with nodular expression in the thyroid gland or with lymph node metastasis have been studied. Initial diagnosis, prediction factors and evolution have been evaluated. Of 18 patients with PTM-NI, 12 demonstrated lymph node metastasis. 6 patients had positive fine needle aspiration (FNA of palpable thyroid nodules. Multifocality and extraglandular extension were associated with lymph node metastasis. Seven of the nine metastatic lymph nodes diagnosed by FNA were cystic. Histologically 83.3% of the nodules in the thyroid were non-encapsulated and showed papillary growth pattern. Multifocality and extrathyroid infiltration were associated with lymph node metastasis at presentation. 46% of the patients with thyroid nodules < 4 mm and lymph node involvement (N1 showed recurrence/persistence. The non-incidental intrathyroideal papillary microcarcinoma without capsular involvement, extraglandular

  18. "Incidental fear cues increase monetary loss aversion": Correction to Schulreich, Gerhardt, and Heekeren (2016).

    Science.gov (United States)

    2016-12-01

    Reports an error in "Incidental fear cues increase monetary loss aversion" by Stefan Schulreich, Holger Gerhardt and Hauke R. Heekeren ( Emotion , 2016[Apr], Vol 16[3], 402-412). In the current article, there was an error in the Study 2 portion of the article. The fourth paragraph of the Results section should read as follows: Performing the same analyses as in Study 1, we found an effect of incidental fear cues on decision behavior. Participants accepted fewer gambles in the fearful-face condition (32.77%) than in the neutral-face condition (33.96%), with Z = -2.187, p = .027, d = -0.998 in the Wilcoxon signed-ranks test and β = 0.012, SE = 0.0053, F(1, 21) = 4.434, p = .047, partial η² = .174 in the linear regression. This suggests increased risk aversion in the fearful-face condition. Concerning personality, however, there were no significant between-subjects effects or between-within interaction effects (all ps = .349). (The following abstract of the original article appeared in record 2015-52358-001.) In many everyday decisions, people exhibit loss aversion-a greater sensitivity to losses relative to gains of equal size. Loss aversion is thought to be (at least partly) mediated by emotional-in particular, fear-related-processes. Decision research has shown that even incidental emotions, which are unrelated to the decision at hand, can influence decision making. The effect of incidental fear on loss aversion, however, is thus far unclear. In two studies, we experimentally investigated how incidental fear cues, presented during (Study 1) or before (Study 2) choices to accept or reject mixed gambles over real monetary stakes, influence monetary loss aversion. We find that the presentation of fearful faces, relative to the presentation of neutral faces, increased risk aversion-an effect that could be attributed to increased loss aversion. The size of this effect was moderated by psychopathic personality: Fearless dominance, in particular its interpersonal facet

  19. Environmental assessment of amine-based carbon capture Scenario modelling with life cycle assessment (LCA)

    Energy Technology Data Exchange (ETDEWEB)

    Brekke, Andreas; Askham, Cecilia; Modahl, Ingunn Saur; Vold, Bjoern Ivar; Johnsen, Fredrik Moltu

    2012-07-01

    This report contains a first attempt at introducing the environmental impacts associated with amines and derivatives in a life cycle assessment (LCA) of gas power production with carbon capture and comparing these with other environmental impacts associated with the production system. The report aims to identify data gaps and methodological challenges connected both to modelling toxicity of amines and derivatives and weighting of environmental impacts. A scenario based modelling exercise was performed on a theoretical gas power plant with carbon capture, where emission levels of nitrosamines were varied between zero (gas power without CCS) to a worst case level (outside the probable range of actual carbon capture facilities). Because of extensive research and development in the areas of solvents and emissions from carbon capture facilities in the latter years, data used in the exercise may be outdated and results should therefore not be taken at face value.The results from the exercise showed: According to UseTox, emissions of nitrosamines are less important than emissions of formaldehyde with regard to toxicity related to operation of (i.e. both inputs to and outputs from) a carbon capture facility. If characterisation factors for emissions of metals are included, these outweigh all other toxic emissions in the study. None of the most recent weighting methods in LCA include characterisation factors for nitrosamines, and these are therefore not part of the environmental ranking.These results shows that the EDecIDe project has an important role to play in developing LCA methodology useful for assessing the environmental performance of amine based carbon capture in particular and CCS in general. The EDecIDe project will examine the toxicity models used in LCA in more detail, specifically UseTox. The applicability of the LCA compartment models and site specificity issues for a Norwegian/Arctic situation will be explored. This applies to the environmental compartments

  20. Examining the durability of incidentally learned trust from gaze cues.

    Science.gov (United States)

    Strachan, James W A; Tipper, Steven P

    2017-10-01

    In everyday interactions we find our attention follows the eye gaze of faces around us. As this cueing is so powerful and difficult to inhibit, gaze can therefore be used to facilitate or disrupt visual processing of the environment, and when we experience this we infer information about the trustworthiness of the cueing face. However, to date no studies have investigated how long these impressions last. To explore this we used a gaze-cueing paradigm where faces consistently demonstrated either valid or invalid cueing behaviours. Previous experiments show that valid faces are subsequently rated as more trustworthy than invalid faces. We replicate this effect (Experiment 1) and then include a brief interference task in Experiment 2 between gaze cueing and trustworthiness rating, which weakens but does not completely eliminate the effect. In Experiment 3, we explore whether greater familiarity with the faces improves the durability of trust learning and find that the effect is more resilient with familiar faces. Finally, in Experiment 4, we push this further and show that evidence of trust learning can be seen up to an hour after cueing has ended. Taken together, our results suggest that incidentally learned trust can be durable, especially for faces that deceive.

  1. Incidental Learning of Gender Agreement in L2.

    Science.gov (United States)

    Denhovska, Nadiia; Serratrice, Ludovica

    2017-10-01

    Incidental learning of grammar has been an area of interest for many decades; nevertheless, existing research has primarily focused on artificial or semi-artificial languages. The present study examines the incidental acquisition of the grammar of a natural language by exposing adult speakers of an ungendered L1 (English) to the gender agreement patterns in Russian (a language that was novel to the learners). Both receptive and productive knowledge and the mediating role of working memory (WM) in learning were measured. Speakers of the ungendered language were able to successfully acquire receptive but not productive grammatical knowledge in a new language under incidental exposure. WM was engaged in production but not in a grammaticality judgment task in the incidental learning condition, indicating cognitive effort during knowledge retrieval.

  2. Esplenectomía incidental: ¿Está justificada?

    Directory of Open Access Journals (Sweden)

    Eddy Sierra Enrique

    1997-12-01

    Full Text Available Se revisaron 77 historias clínicas de pacientes que presentaban lesiones incidentales del bazo ocurridas entre 1985 y 1994, durante operaciones intraabdominales y por examen laparoscópico. Las funciones inmunológicas del bazo y su papel contra las infecciones están bien definidas, por lo cual al ser suprimido este órgano a consecuencia de lesiones incidentales, favorecen las infecciones en dichos pacientes de por vida. De las 77 lesiones incidentales se realizaron 47(61 % esplenectomías incidentales y 30(39 % cirugías conservadoras. La úlcera duodenal y la hernia hiatal son las causas principales de esplenectomía incidental. Se presentaron 11 infecciones (23,4 % y 1 fallecido (2,1 % en la esplenectomía incidental contra 1 infección (3,3 % y ningún fallecido en la cirugía conservadora. Se llega a la conclusión de que la esplenectomía no está justificada dadas las desventajas que presenta77 medical histories of patients who presented incidental injuries of the spleen occurred between 1985 and 1994, during intraabdominal operations and by laparoscopic examination, were reviewed. The immunological functions of the spleen and its role against infections are well defined, so the removal of this organ due to incidental injuries favors the appearance of infections in these patients for the rest of their lives. Of the 77 incidental injuries 47 (61 % incidental splenectomies and 30 (39 % conservative surgeries were performed. Duodenal ulcer and hiatal hernia proved to be the main causes of incidental splenectomy. There were 11 infections (23.4 % and 1 death (2.1 % in the incidental splenectomy compared with 1 infection (3.3 % and no death in the conservative surgery. It is concluded that splenectomy is not justified because of its disadvantages

  3. Life cycle assessment (LCA) of an energy recovery plant in the olive oil industries

    Energy Technology Data Exchange (ETDEWEB)

    Intini, Francesca; Kuhtz, Silvana [Dep. Engineering and Environmental Physics, Faculty of Engineering, University of Basilicata (Italy); Gianluca Rospi, [Dep. Engineering and Environmental Physics, Faculty of Architecture, University of Basilicata (Italy)

    2012-07-01

    To reduce the GHG emissions in the UE and to increase the produced energy it is important to spread out decentralized technologies for renewable energy production. In this paper a power plant fed with biomass is studied, in particular the biomass considered is the waste of the olive oil industries. This study focuses on the possibility of using the de-oiled pomace and waste wood as fuel. A life cycle assessment (LCA) of a biomass power plant located in the South of Italy was performed. The global warming potential has been calculated and compared with that of a plant for energy production that uses refuse derived fuel (RDF) and that of one that uses coal. The LCA shows the important environmental advantages of biomass utilization in terms of greenhouse gas emissions reduction. An improved impact assessment methodology may better underline the advantages due to the biomass utilization.

  4. Intervenção da fisioterapia após ligamentoplastia do LCA

    OpenAIRE

    Bonança, Daniela

    2014-01-01

    RESUMO: Objectivo: Este estudo teve por objectivo descrever a prática clínica e os resultados da intervenção da fisioterapia, às 6, 12 e 24 semanas, em indivíduos após ligamentoplastia do LCA. Introdução: O sucesso da ligamentoplastia do LCA está directamente relacionado com a reabilitação após a realização da mesma, permitindo ao utente o retorno a um estilo de vida activo. Apesar de se saber que um programa de reabilitação estruturado e baseado na evidência tem um papel fulcral nos resul...

  5. Life cycle assessment of waste incineration in Denmark and Italy using two LCA models

    DEFF Research Database (Denmark)

    Turconi, Roberto; Butera, Stefania; Boldrin, Alessio

    2011-01-01

    In Europe, about 20% of municipal solid waste is incinerated. Large differences can be found between northern and southern Europe regarding energy recovery efficiencies, flue gas cleaning technologies and residue management. Life-cycle assessment (LCA) of waste incineration often provides....... The overall environmental performance of the Danish system was better than the Italian, mainly because of higher heat recovery at the Danish plant. Flue gas cleaning at the Italian plant was, however, preferable to the Danish, indicating that efficient flue gas cleaning may provide significant benefits...... contradictory results if these local conditions are not properly accounted for. The importance of regional differences and site-specific data, and choice of LCA model itself, was evaluated by assessment of two waste incinerators representing northern and southern Europe (Denmark and Italy) based on two...

  6. Estimation of product specific emissions from municipal solid waste landfills for the inventory phase in LCA

    DEFF Research Database (Denmark)

    Nielsen, Per Henning; Hauschild, Michael Zwicky

    1998-01-01

    is frequently given as a quantity of solid wasteand possibly some recovered energy from waste incineration.Since product specific emissions can not be calculated or measured directly at the landfills, they must be estimated by modeling oflandfill processes. This paper presents a landfill model based on a large......), and inorganic non-metals (e.g. chlorine,) which are considered individually. The computer toolLCA-LAND is useful for estimation of emissions from specific waste products disposed in municipal solid waste landfills in Europeancountries (for the present Denmark, Germany and The Netherlands). Input data...... of materials and components and the manufacture, transportation and use of the product to thefinal disposal and possible recycling of the product. Although LCA has developed significantly during recent years, product specific emissions from disposed waste have only got minorattention in the literature leaving...

  7. Life cycle assessment (LCA) of electricity generation technologies: Overview, comparability and limitations

    DEFF Research Database (Denmark)

    Turconi, Roberto; Boldrin, Alessio; Astrup, Thomas Fruergaard

    2013-01-01

    , nuclear, biomass, hydroelectric, solar photovoltaic (PV) and wind was carried out to identify ranges of emission data for GHG, NOx and SO2 related to individual technologies. It was shown that GHG emissions could not be used as a single indicator to represent the environmental performance of a system...... identified as follows: the energy recovery efficiency and the flue gas cleaning system for fossil fuel technologies; the electricity mix used during both the manufacturing and the construction phases for nuclear and renewable technologies; and the type, quality and origin of feedstock, as well as the amount....... The most critical methodological aspects in relation to LCA studies were identified as follows: definition of the functional unit, the LCA method employed (e.g., IOA, PCA and hybrid), the emission allocation principle and/or system boundary expansion. The most important technological aspects were...

  8. Optimal utilization of waste-to-energy in an LCA perspective

    DEFF Research Database (Denmark)

    Fruergaard, Thilde; Astrup, Thomas

    2011-01-01

    Energy production from two types of municipal solid waste was evaluated using life cycle assessment (LCA): (1) mixed high calorific waste suitable for production of solid recovered fuels (SRF) and (2) source separated organic waste. For SRF, co-combustion was compared with mass burn incineration....... For organic waste, anaerobic digestion (AD) was compared with mass burn incineration. In the case of mass burn incineration, incineration with and without energy recovery was modelled. Biogas produced from anaerobic digestion was evaluated for use both as transportation fuel and for heat and power production....... All relevant consequences for energy and resource consumptions, emissions to air, water and soil, upstream processes and downstream processes were included in the LCA. Energy substitutions were considered with respect to two different energy systems: a present-day Danish system based on fossil fuels...

  9. Exposure to chemicals in food packaging as a sustainability trade-off in LCA

    DEFF Research Database (Denmark)

    Ernstoff, Alexi; Muncke, Jane; Trier, Xenia

    2016-01-01

    Hazardous chemicals in packaging, including ‘eco-friendly’ and recycled food packaging, can migrate into food and expose humans. LCA has been fundamental to indicate more ‘eco-friendly’ packages, but currently LCA does not consider exposure to chemical migrants and methods have not yet been...... but to provide life cycle context to compare the magnitude of characterized exposure to chemicals in packaging, in order to elucidate if this exposure pathway is important. We detail estimates of life cycle exposure to one known hazardous chemical in polystyrene packaging (styrene) that has data available...... developed. In this study we question if exposure to chemicals in food packaging should be considered as a sustainable design consideration, i.e. if this human health risk is relevant in a life cycle context. To answer this question, we focus on developing methods to quantify exposure to chemicals in food...

  10. Environmental sustainable decision making – The need and obstacles for integration of LCA into decision analysis

    DEFF Research Database (Denmark)

    Dong, Yan; Miraglia, Simona; Manzo, Stefano

    2018-01-01

    systems, revealing potential problem shifting between life cycle stages. Through the integration with traditional risk based decision analysis, LCA may thus facilitate a better informed decision process. In this study we explore how environmental impacts are taken into account in different fields......Decision analysis is often used to help decision makers choose among alternatives, based on the expected utility associated to each alternative as function of its consequences and potential impacts. Environmental impacts are not always among the prioritized concerns of traditional decision making...... of interest for decision makers to identify the need, potential and obstacles for integrating LCA into conventional approaches to decision problems. Three application areas are used as examples: transportation planning, flood management, and food production and consumption. The analysis of these cases shows...

  11. Differentiating the influence of incidental anger and fear on risk decision-making.

    Science.gov (United States)

    Yang, Qiwei; Zhao, Ding; Wu, Yan; Tang, Ping; Gu, Ruolei; Luo, Yue-Jia

    2018-02-01

    Previous research has revealed that incidental emotions of different valence (positive/negative/neutral) produce distinct impacts on risk decision-making. This study went on to compare the effects of different emotions of which the valence are identical. We focused on anger and fear, both of which are negative emotions but differ in motivational and appraisal dimensions. Participants finished a forced-choice gambling task, during which incidental emotions (anger/fear/happy) were elicited by facial stimuli selected from the Chinese Facial Affective Picture System. Behavioral and event-related potential (ERP) data were recorded in the experiment, which showed that anger and fear were different in their influence on behavioral risk preference and the relationship between outcome processing and subsequent risk decisions. Regarding the behavioral results, risk preference in the anger condition was higher than the fear condition, but lower than the happy condition. Regarding the ERP results elicited by outcome feedback (gain/loss), in the fear condition, the feedback-related negativity (FRN) was positively correlated with risk preference; in the anger condition, the gain-related P3 component was positively correlated with risk preference; in the happy condition, both the FRN and the loss-related P3 was negatively correlated with risk preference. The current findings provide novel insight into distinguishing the effect of different incidental emotions on risk preference. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Prevalence of incidental thyroid nodules in ultrasound studies of dogs with hypercalcemia (2008-2013).

    Science.gov (United States)

    Pollard, Rachel E; Bohannon, Laurie K; Feldman, Edward C

    2015-01-01

    Ultrasound is commonly used to evaluate the cervical region in dogs with hypercalcemia due to suspected hyperparathyroidism. Incidental thyroid nodules may be detected during these studies, however little information has been published to guide clinical decision-making when this occurs. The purpose of this cross-sectional study was to determine the prevalence of incidental thyroid nodules in hypercalcemic dogs undergoing cervical ultrasound at our hospital during the period of 2008-2013. Dogs with a palpable neck mass were excluded. Cervical ultrasound images for each dog were retrieved and reviewed by a board certified veterinary radiologist who was unaware of patient outcome. Presence, number, and dimensions of thyroid nodules were recorded. Results of thyroid nodule aspirate, biopsy or necropsy were recorded from medical records when available. Ninety-one dogs met inclusion criteria. Of these, 14/91 (15%) dogs had at least one thyroid nodule. Mean (± standard deviation) thyroid gland nodule length, width, and height were 1.51 ± 0.74, 0.96 ± 0.73, and 0.75 ± 0.36 cm, respectively. A histologic diagnosis was available for the incidental thyroid lesions in eight dogs, including one dog with two nodules. Confirmed diagnoses for these nodules were thyroid cyst (3/9, 33%), thyroid adenoma (3/9, 33%), thyroid adenocarcinoma (2/9, 22%) and nodular hyperplasia (1/9, 11%). Findings indicated that incidental thyroid nodules may be present in hypercalcemic dogs with no palpable neck mass and no clinical signs of thyroid disease. Some of these nodules may be malignant and therefore a recommendation for cytology or biopsy may be justified. © 2014 American College of Veterinary Radiology.

  13. Incidental mood state before dissonance induction affects attitude change.

    Directory of Open Access Journals (Sweden)

    Marie-Amélie Martinie

    Full Text Available The way that incidental affect impacts attitude change brought about by controlled processes has so far been examined when the incidental affective state is generated after dissonance state induction. We therefore investigated attitude change when the incidental mood occurs prior to dissonance state induction. We expected a negative mood to induce systematic processing, and a positive mood to induce heuristic processing. Given that both systematic processing and attitude change are cognitively costly, we expected participants who experienced the dissonance state in a negative mood to have insufficient resources to allocate to attitude change. In our experiment, after mood induction (negative, neutral or positive, participants were divided into low-dissonance and high-dissonance groups. They then wrote a counterattitudinal essay. Analysis of their attitudes towards the essay topic indicated that attitude change did not occur in the negative incidental mood condition. Moreover, written productivity-one indicator of cognitive resource allocation-varied according to the type of incidental mood, and only predicted attitude change in the high-dissonance group. Our results suggest that incidental mood before dissonance induction influences the style of information processing and, by so doing, affects the extent of attitude change.

  14. Accounting for ecosystem services in Life Cycle Assessment, Part II: toward an ecologically based LCA.

    Science.gov (United States)

    Zhang, Yi; Baral, Anil; Bakshi, Bhavik R

    2010-04-01

    Despite the essential role of ecosystem goods and services in sustaining all human activities, they are often ignored in engineering decision making, even in methods that are meant to encourage sustainability. For example, conventional Life Cycle Assessment focuses on the impact of emissions and consumption of some resources. While aggregation and interpretation methods are quite advanced for emissions, similar methods for resources have been lagging, and most ignore the role of nature. Such oversight may even result in perverse decisions that encourage reliance on deteriorating ecosystem services. This article presents a step toward including the direct and indirect role of ecosystems in LCA, and a hierarchical scheme to interpret their contribution. The resulting Ecologically Based LCA (Eco-LCA) includes a large number of provisioning, regulating, and supporting ecosystem services as inputs to a life cycle model at the process or economy scale. These resources are represented in diverse physical units and may be compared via their mass, fuel value, industrial cumulative exergy consumption, or ecological cumulative exergy consumption or by normalization with total consumption of each resource or their availability. Such results at a fine scale provide insight about relative resource use and the risk and vulnerability to the loss of specific resources. Aggregate indicators are also defined to obtain indices such as renewability, efficiency, and return on investment. An Eco-LCA model of the 1997 economy is developed and made available via the web (www.resilience.osu.edu/ecolca). An illustrative example comparing paper and plastic cups provides insight into the features of the proposed approach. The need for further work in bridging the gap between knowledge about ecosystem services and their direct and indirect role in supporting human activities is discussed as an important area for future work.

  15. The 2d-LCA as an alternative to x-wires

    Science.gov (United States)

    Puczylowski, Jaroslaw; Hölling, Michael; Peinke, Joachim

    2015-11-01

    The 2d-Laser Cantilever Anemometer (2d-LCA) is an innovative sensor for two-dimensional velocity measurements in fluids. It uses a micostructured cantilever made of silicon and SU-8 as a sensing element and is capable of performing mesurements with extremly high temporal resolutions up to 150kHz. The size of the cantilever defines its spatial resolution, which is in the order of 150 μm only. Another big feature is a large angular range of 180° in total. The 2d-LCA has been developed as an alternative measurement method to x-wires with the motivation to create a sensor that can operate in areas where the use of hot-wire anemometry is difficult. These areas include measurements in liquids and in near-wall or particle-laden flows. Unlike hot-wires, the resolution power of the 2d-LCA does not decrease with increasing flow velocity, making it particularly suitable for measurements in high speed flows. Comparative measurements with the 2d-LCA and hot-wires have been carried out in order to assess the performance of the new anemometer. The data of both measurement techniques were analyzed using the same stochastic methods including a spectral analysis as well as an inspection of increment statistics and structure functions. Furthermore, key parameters, such as mean values of both velocity components, angles of attack and the characteristic length scales were determined from both data sets. The analysis reveals a great agreement between both anemometers and thus confirms the new approach.

  16. Evaluation of Environmental Impacts for Rice Agroecosystems using Life Cycle Assessment (LCA)

    OpenAIRE

    S. Khoramdel; J. Shabahang; A. Amin Ghafouri

    2017-01-01

    In order to evaluate life cycle assessment (LCA) for rice agroecosystems based on mean of nitrogen fertilizer levels (less than 190, 190-200, 200-210, 210-220 and more than 220 kg N ha) during 1999-2012, an experiment was conducted. Four steps includung goal definition and scoping, inventory analysis, life cycle impact assessment and integration and interpretation were computed. Functional unit was considered as one tone paddy. Impact categories were acidification, eutrophication in aquatic a...

  17. Revision and extension of Eco-LCA metrics for sustainability assessment of the energy and chemical processes.

    Science.gov (United States)

    Yang, Shiying; Yang, Siyu; Kraslawski, Andrzej; Qian, Yu

    2013-12-17

    Ecologically based life cycle assessment (Eco-LCA) is an appealing approach for the evaluation of resources utilization and environmental impacts of the process industries from an ecological scale. However, the aggregated metrics of Eco-LCA suffer from some drawbacks: the environmental impact metric has limited applicability; the resource utilization metric ignores indirect consumption; the renewability metric fails to address the quantitative distinction of resources availability; the productivity metric seems self-contradictory. In this paper, the existing Eco-LCA metrics are revised and extended for sustainability assessment of the energy and chemical processes. A new Eco-LCA metrics system is proposed, including four independent dimensions: environmental impact, resource utilization, resource availability, and economic effectiveness. An illustrative example of comparing assessment between a gas boiler and a solar boiler process provides insight into the features of the proposed approach.

  18. LCA as an environmental technology development performance indicator of engineered nano-materials and their application in polymers

    DEFF Research Database (Denmark)

    Miseljic, Mirko; Olsen, Stig Irving; Hauschild, Michael Zwicky

    project is aimed to be holistic and thereby include the entire life cycle of the nano‐polymer products and not be like the current frequently applied nano‐material LCA case study approaches where the life cycle is reduced and system boundaries substantially limited. In order to perform accurate......Engineered nano‐material (ENM) application in products has in recent years developed to an important market segment but with rising environmental concerns, as the environmental life cycle impacts, especially toxicity of nanoparticles, are not assessed. Life cycle assessment (LCA) is a holistic tool...... to the conventional ways of attaining these in the polymer product industry. To assure environmental sustainability LCA will be performed within the MINANO project and more precisely comparing the new ENM technology and the conventional technology approach to attain the same functionalities. The LCA in the MINANO...

  19. Review of LCA studies of solid waste management systems – Part II: Methodological guidance for a better practice

    DEFF Research Database (Denmark)

    Laurent, Alexis; Clavreul, Julie; Bernstad, Anna

    2014-01-01

    conduct of the LCA. How has LCA been applied until now? Are there any inconsistencies in the past practice? To answer these questions, we draw on a critical review of 222 published LCA studies of solid waste management systems. We analyse the past practice against the ISO standard requirements......Life cycle assessment (LCA) is increasingly used in waste management to identify strategies that prevent or minimise negative impacts on ecosystems, human health or natural resources. However, the quality of the provided support to decision- and policy-makers is strongly dependent on a proper...... compositions into the inventory, and a frequent lack of essential sensitivity and uncertainty analyses. Many of these aspects are important for the reliability of the results. For each of them, we therefore provide detailed recommendations to practitioners of waste management LCAs. © 2013 Elsevier Ltd. All...

  20. Analysis and Assessment of Environmental Load of Vending Machines by a LCA Method, and Eco-Improvement Effect

    Science.gov (United States)

    Kimura, Yukio; Sadamichi, Yucho; Maruyama, Naoki; Kato, Seizo

    These days the environmental impact due to vending machines'(VM) diffusion has greatly been discussed. This paper describes the numerical evaluation of the environmental impact by using the LCA (Life Cycle Assessment) scheme and then proposes eco-improvements' strategy toward environmentally conscious products(ECP). A new objective and universal consolidated method for the LCA-evaluation, so-called LCA-NETS(Numerical Eco-load Standardization ) developed by the authors is applied to the present issue. As a result, the environmental loads at the 5years' operation and the material procurement stages are found to dominate others over the life cycle. Further eco-improvement is realized by following the order of the LCA-NETS magnitude; namely, energy saving, materials reducing, parts' re-using, and replacing with low environmental load material. Above all, parts' re-using is specially recommendable for significant reduction of the environmental loads toward ECP.

  1. Crop residues as raw materials for biorefinery systems - A LCA case study

    International Nuclear Information System (INIS)

    Cherubini, Francesco; Ulgiati, Sergio

    2010-01-01

    Our strong dependence on fossil fuels results from the intensive use and consumption of petroleum derivatives which, combined with diminishing oil resources, causes environmental and political concerns. The utilization of agricultural residues as raw materials in a biorefinery is a promising alternative to fossil resources for production of energy carriers and chemicals, thus mitigating climate change and enhancing energy security. This paper focuses on a biorefinery concept which produces bioethanol, bioenergy and biochemicals from two types of agricultural residues, corn stover and wheat straw. These biorefinery systems are investigated using a Life Cycle Assessment (LCA) approach, which takes into account all the input and output flows occurring along the production chain. This approach can be applied to almost all the other patterns that convert lignocellulosic residues into bioenergy and biochemicals. The analysis elaborates on land use change aspects, i.e. the effects of crop residue removal (like decrease in grain yields, change in soil N 2 O emissions and decrease of soil organic carbon). The biorefinery systems are compared with the respective fossil reference systems producing the same amount of products/services from fossils instead of biomass. Since climate change mitigation and energy security are the two most important driving forces for biorefinery development, the assessment focuses on greenhouse gas (GHG) emissions and cumulative primary energy demand, but other environmental categories are evaluated as well. Results show that the use of crop residues in a biorefinery saves GHG emissions and reduces fossil energy demand. For instance, GHG emissions are reduced by about 50% and more than 80% of non-renewable energy is saved. Land use change effects have a strong influence in the final GHG balance (about 50%), and their uncertainty is discussed in a sensitivity analysis. Concerning the investigation of the other impact categories, biorefinery systems

  2. LCA of strippable coatings and of steam vacuum technology used for nuclear plants decontamination

    International Nuclear Information System (INIS)

    Guidi, Giambattista; Cumo, Fabrizio; Santoli, Livio de

    2010-01-01

    The application of strippable coatings is an innovative technology for decontamination of nuclear plants and for any decontamination project aiming at removing surface contamination. An adhesive plastic coating is applied on the contaminated surface. The strippable coating is allowed to cure for up to 24 h, after which it can be easily peeled. The coating traps the contaminants in the polymer matrix. Strippable coatings are non-toxic and do not contain volatile compounds or heavy metals. Since the coating constitutes a solid waste, disposal is easier than treating contaminated liquid wastes, produced by the baseline technology: steam vacuum cleaning, based upon superheated pressurized water in order to remove contaminants from floors and walls. A life cycle assessment (LCA) has been carried out with the purpose of comparing the strippable coating with the steam vacuum technology. The functional unit of the study is represented by a surface of 1 m 2 to be decontaminated. The results of LCA achieved using Sima Pro 5.0 registered software confirm the good environmental performances of strippable coatings. Taking into account both LCA and environmental costs for liquid wastes, the advantages of strippable coatings will be more and more evident. (orig.)

  3. LCA applied to elucidate opportunities for biogas from wastewaters in Colombia.

    Science.gov (United States)

    Meneses-Jácome, A; Osorio-Molina, A; Parra-Saldívar, R; Gallego-Suárez, D; Velásquez-Arredondo, H I; Ruiz-Colorado, A A

    2015-01-01

    Biogas produced in municipal and industrial wastewater treatment facilities (BWWF) is a resource wasted in several socio-economic contexts. BWWF-based projects are compared against energy projects using conventional electricity or natural gas (NG), following strict economic considerations that usually tip the balance in favour of conventional energy supply. This is because the economic gain associated with the environmental benefits of using small biogas sources like BWWF does not overcome the technical and financial effort required in these types of project. This paper shows a broader application of life cycle assessment (LCA) methodology to explore opportunities for positive (or effective) utilization of BWWF in the Colombian context. LCA has been used to evaluate the supply-chain of NG which is the direct competitor of BWWF, in three different Colombian regions, in order to identify those where higher NG environmental impacts offer increased environmental added-value to BWWF use. LCA was also applied to study two BWWF valorization scenarios in the poultry processing industry. It shows how valorization options for BWWF are more realistic and effective when specific-regional loads are applied to the environmental assessment of NG supply-chain and BWWF valorization.

  4. Carbon Reduction Measures-Based LCA of Prefabricated Temporary Housing with Renewable Energy Systems

    Directory of Open Access Journals (Sweden)

    Ling Dong

    2018-03-01

    Full Text Available Temporary housing plays an important role in providing secure, hygienic, private, and comfortable shelter in the aftermath of disaster (such as flood, fire, earthquake, etc.. Additionally, temporary housing can also be used as a sustainable form of on-site residences for construction workers. While most of the building components used in temporary housing can be manufactured in a plant, prefabrication technology improves the production efficiency of temporary housing; furthermore, integrated renewable energy systems, for example, solar photovoltaic (PV system, offer benefits for temporary housing operations. In order to assess the environmental impacts of prefabricated temporary housing equipped with renewable energy systems, this study first divides the life cycle of temporary housing into six stages, and then establishes a life cycle assessment (LCA model for each stage. Furthermore, with the aim of reducing the environmental impacts, life cycle carbon reduction measures are proposed for each stage of temporary housing. The proposed methodology is demonstrated using a case study in China. Based on the proposed carbon reduction measures, the LCA of a prefabricated temporary housing case study building equipped with renewable energy systems indicates a carbon emissions intensity of 35.7 kg/m2·per year, as well as a reduction in material embodied emissions of 18%, assembly emissions of 17.5%, and operational emissions of 91.5%. This research proposes a carbon reduction-driven LCA of temporary housing and contributes to promoting sustainable development of prefabricated temporary housing equipped with renewable energy systems.

  5. Production of recyclates – compared with virgin Plastics – a LCA Study

    Directory of Open Access Journals (Sweden)

    Storm Birgit Kjærside

    2017-01-01

    Full Text Available Plastix A/S is a Danish cleantech company transforming discarded fishing trawls and nets into valuable green raw materials. Plastix– technology and processes solve a maritime waste problem and contribute to a more circular green economy and reduce landfilling, marine pollution, CO2 emissions and especially loss of valuable resources. Plastix– recycling technology enables recovery of discarded fishing trawls and nets via mechanical and thermal processes transforming the waste into valuable recycles which can be converted into plastic products replacing virgin raw materials. The performance has been proved through a Life Cycle Assessment (LCA study. The results from the LCA study are compared with the production of virgin materials. The results of the LCA show that especially the carbon footprint is remarkable better for Oceanix than for virgin plastics. Oceanix HDPE is 5 times better than virgin HDPE, when talking about the carbon foot print, and the results for Oceanix PP and Oceanix PA6 are 5 times and 20 times better compared with virgin PP and PA6. Also other environmental indicators are better for Oceanix compared with virgin plastics.

  6. Minimization of the LCA impact of thermodynamic cycles using a combined simulation-optimization approach

    International Nuclear Information System (INIS)

    Brunet, Robert; Cortés, Daniel; Guillén-Gosálbez, Gonzalo; Jiménez, Laureano; Boer, Dieter

    2012-01-01

    This work presents a computational approach for the simultaneous minimization of the total cost and environmental impact of thermodynamic cycles. Our method combines process simulation, multi-objective optimization and life cycle assessment (LCA) within a unified framework that identifies in a systematic manner optimal design and operating conditions according to several economic and LCA impacts. Our approach takes advantages of the complementary strengths of process simulation (in which mass, energy balances and thermodynamic calculations are implemented in an easy manner) and rigorous deterministic optimization tools. We demonstrate the capabilities of this strategy by means of two case studies in which we address the design of a 10 MW Rankine cycle modeled in Aspen Hysys, and a 90 kW ammonia-water absorption cooling cycle implemented in Aspen Plus. Numerical results show that it is possible to achieve environmental and cost savings using our rigorous approach. - Highlights: ► Novel framework for the optimal design of thermdoynamic cycles. ► Combined use of simulation and optimization tools. ► Optimal design and operating conditions according to several economic and LCA impacts. ► Design of a 10MW Rankine cycle in Aspen Hysys, and a 90kW absorption cycle in Aspen Plus.

  7. Minimization of the LCA impact of thermodynamic cycles using a combined simulation-optimization approach

    Energy Technology Data Exchange (ETDEWEB)

    Brunet, Robert; Cortes, Daniel [Departament d' Enginyeria Quimica, Escola Tecnica Superior d' Enginyeria Quimica, Universitat Rovira i Virgili, Campus Sescelades, Avinguda Paisos Catalans 26, 43007 Tarragona (Spain); Guillen-Gosalbez, Gonzalo [Departament d' Enginyeria Quimica, Escola Tecnica Superior d' Enginyeria Quimica, Universitat Rovira i Virgili, Campus Sescelades, Avinguda Paisos Catalans 26, 43007 Tarragona (Spain); Jimenez, Laureano [Departament d' Enginyeria Quimica, Escola Tecnica Superior d' Enginyeria Quimica, Universitat Rovira i Virgili, Campus Sescelades, Avinguda Paisos Catalans 26, 43007 Tarragona (Spain); Boer, Dieter [Departament d' Enginyeria Mecanica, Escola Tecnica Superior d' Enginyeria, Universitat Rovira i Virgili, Campus Sescelades, Avinguda Paisos Catalans 26, 43007, Tarragona (Spain)

    2012-12-15

    This work presents a computational approach for the simultaneous minimization of the total cost and environmental impact of thermodynamic cycles. Our method combines process simulation, multi-objective optimization and life cycle assessment (LCA) within a unified framework that identifies in a systematic manner optimal design and operating conditions according to several economic and LCA impacts. Our approach takes advantages of the complementary strengths of process simulation (in which mass, energy balances and thermodynamic calculations are implemented in an easy manner) and rigorous deterministic optimization tools. We demonstrate the capabilities of this strategy by means of two case studies in which we address the design of a 10 MW Rankine cycle modeled in Aspen Hysys, and a 90 kW ammonia-water absorption cooling cycle implemented in Aspen Plus. Numerical results show that it is possible to achieve environmental and cost savings using our rigorous approach. - Highlights: Black-Right-Pointing-Pointer Novel framework for the optimal design of thermdoynamic cycles. Black-Right-Pointing-Pointer Combined use of simulation and optimization tools. Black-Right-Pointing-Pointer Optimal design and operating conditions according to several economic and LCA impacts. Black-Right-Pointing-Pointer Design of a 10MW Rankine cycle in Aspen Hysys, and a 90kW absorption cycle in Aspen Plus.

  8. Regional characterization of freshwater Use in LCA: modeling direct impacts on human health.

    Science.gov (United States)

    Boulay, Anne-Marie; Bulle, Cécile; Bayart, Jean-Baptiste; Deschênes, Louise; Margni, Manuele

    2011-10-15

    Life cycle assessment (LCA) is a methodology that quantifies potential environmental impacts for comparative purposes in a decision-making context. While potential environmental impacts from pollutant emissions into water are characterized in LCA, impacts from water unavailability are not yet fully quantified. Water use can make the resource unavailable to other users by displacement or quality degradation. A reduction in water availability to human users can potentially affect human health. If financial resources are available, there can be adaptations that may, in turn, shift the environmental burdens to other life cycle stages and impact categories. This paper proposes a model to evaluate these potential impacts in an LCA context. It considers the water that is withdrawn and released, its quality and scarcity in order to evaluate the loss of functionality associated with water uses. Regionalized results are presented for impacts on human health for two modeling approaches regarding affected users, including or not domestic uses, and expressed in disability-adjusted life years (DALY). A consumption and quality based scarcity indicator is also proposed as a midpoint. An illustrative example is presented for the production of corrugated board with different effluents, demonstrating the importance of considering quality, process effluents and the difference between the modeling approaches.

  9. Comparative life cycle assessment (LCA) of biodiesel and fossil diesel fuel

    International Nuclear Information System (INIS)

    Spirinckx, C.; Xeuterick, D.

    1997-01-01

    Complementary to VlTO's demonstration project on the use of biodiesel as engine fuel (including on the road emission measurements) in Flanders, Belgium, a comparative life cycle assessment (LCA) has been carried out for rapeseed methyl ester (RME) and fossil diesel fuel. The primary concern of this study is the question as to whether or not the production of biodiesel is comparable to the production of fossil diesel fuel from an environmental point of view, taking into account all stages of the life cycle of these two products. The study covers: (1) a description of the LCA methodology used; (2) a definition of the goal and scope of the study: (3) an inventory of the consumption of energy and materials and the discharges to the environment, from the cradle to the grave, for both alternative fuels: (4) a comparative impact assessment; and (5) the interpretation of the results. The results of this comparative LCA can be used in the final decision making process next to the results of a social and economical assessment. 6 refs

  10. Sandstorm appearance of pulmonary alveolar microlithiasis incidentally detected in a young, asymptomatic male

    Energy Technology Data Exchange (ETDEWEB)

    Ching, Li Shyan; Bux, Shaik Ismail; Liam, Chong Kin; Rahman, Nazarina Abdul; Ho, Choon Yan [Faculty of Medicine, University Malaya Medical Center, Kuala Lumpur (Malaysia)

    2013-10-15

    Pulmonary alveolar microlithiasis (PAM) is a rare chronic disease with paucity of symptoms in contrast to the imaging findings. We present a case of a 24-year-old Malay man having an incidental abnormal pre-employment chest radiograph of dense micronodular opacities giving the classical 'sandstorm' appearance. High-resolution computed tomography of the lungs showed microcalcifications with subpleural cystic changes. Open lung biopsy showed calcospherites within the alveolar spaces. The radiological and histopathological findings were characteristic of PAM.

  11. Evaluation of the effect of accounting method, IPCC v. LCA, on grass-based and confinement dairy systems' greenhouse gas emissions.

    Science.gov (United States)

    O'Brien, D; Shalloo, L; Patton, J; Buckley, F; Grainger, C; Wallace, M

    2012-09-01

    Life cycle assessment (LCA) and the Intergovernmental Panel on Climate Change (IPCC) guideline methodology, which are the principal greenhouse gas (GHG) quantification methods, were evaluated in this study using a dairy farm GHG model. The model was applied to estimate GHG emissions from two contrasting dairy systems: a seasonal calving pasture-based dairy farm and a total confinement dairy system. Data used to quantify emissions from these systems originated from a research study carried out over a 1-year period in Ireland. The genetic merit of cows modelled was similar for both systems. Total mixed ration was fed in the Confinement system, whereas grazed grass was mainly fed in the grass-based system. GHG emissions from these systems were quantified per unit of product and area. The results of both methods showed that the dairy system that emitted the lowest GHG emissions per unit area did not necessarily emit the lowest GHG emissions possible for a given level of product. Consequently, a recommendation from this study is that GHG emissions be evaluated per unit of product given the growing affluent human population and increasing demand for dairy products. The IPCC and LCA methods ranked dairy systems' GHG emissions differently. For instance, the IPCC method quantified that the Confinement system reduced GHG emissions per unit of product by 8% compared with the grass-based system, but the LCA approach calculated that the Confinement system increased emissions by 16% when off-farm emissions associated with primary dairy production were included. Thus, GHG emissions should be quantified using approaches that quantify the total GHG emissions associated with the production system, so as to determine whether the dairy system was causing emissions displacement. The IPCC and LCA methods were also used in this study to simulate, through a dairy farm GHG model, what effect management changes within both production systems have on GHG emissions. The findings suggest that

  12. Dose assessment under incidental and accidental conditions

    International Nuclear Information System (INIS)

    Huebschmann, W.G.

    1988-01-01

    Dose assessment for the licesing process of a nuclear power plant covers the routine release of radioactive substances into the atmosphere as well as releases due to incidents. Source terms for these incidents are evaluated by the detailed incident analysis of the plant. The types of incidents to be covered are determined in the FRG by the ''Stoerfall-Leitlinien'' of the Ministry of the Interior. The calculation of dose equivalents in the environment of the plant differs from the calculation of doses due to routine releases, as incidents are single events occuring at undeterminate time, and the results must be conservative. Some details are being described. During the operation of the plant it is essential to measure not only the radioactivity release rates but also the necessary meteorological parameters for the instantaneous determination of the atmospheric dispersion in case of incidental or accidental releases of radioactivity. This instantaneous assessment assists in taking measurements of ground contamination and in deciding about countermeasures for the protection of plant personnell and population. (author) [pt

  13. Incidental Vocabulary Learning: A Semantic Field Approach

    Directory of Open Access Journals (Sweden)

    Parvaneh Khosravizadeh

    2011-10-01

    Full Text Available

    This study is an attempt to explore the difference between acquiring new words with different semantic fields to which they belong. In other words, the purpose of this study is to scrutinize the contribution of semantic field theory in learning new vocabulary items in an EFL setting. Thirty-eight students of three different levels of education took part in this research. They were exposed to some new words from four different semantic fields, and then they were tested on their acquisition of the words meaning. This exposure was through reading texts and the aim of reading was just comprehension, therefore the words were acquired incidentally. The outcome showed significant differences between groups with different levels of education regarding retention of words from different semantic fields.

  14. Asymptomatic young man with an incidental murmur.

    Science.gov (United States)

    Shojaeifard, Maryam; Pouraliakbar, Hamid Reza; Houshmand, Golnaz

    2018-05-31

    A 32-year old man was referred to our institution for transthoracic echocardiography (TTE) following detection of an incidental murmur on physical examination before blood donation. He was asymptomatic with no significant medical history. Physical examination revealed dual heart sounds with a grade II/VI systolic murmur heard in the left sternal border. An ECG was in normal sinus rhythm. TTE was performed (figure 1A-C, online supplementary videos 1-4) followed by cardiac CT angiography (CTA) (figure 1D,E).heartjnl;heartjnl-2018-313223v1/F1F1F1Figure 1(A) Transthoracic echocardiography, parasternal left ventricular long axis view. (B) Colour Doppler of modified short axis in the mid-left ventricular level. (C) Doppler flow velocity profile. (D) Cardiac CT angiography (CTA) sagittal reconstruction. (E) Three-dimensional CTA reconstruction of the heart. What is the diagnosis?Pericardial cyst.Ventricular septal defect.Kawasaki.Anomalous left coronary artery from pulmonary artery (ALCAPA). © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  15. Incidental placental choriocarcinoma in a term pregnancy: a case report

    Directory of Open Access Journals (Sweden)

    Chung Christopher

    2008-10-01

    Full Text Available Abstract Introduction Gestational choriocarcinoma occurs in 1 in 40,000 pregnancies. Of all forms of gestational choriocarcinoma, placental choriocarcinoma is the most rare. Maternal choriocarcinoma is usually diagnosed in symptomatic patients with metastases. The incidental finding of a choriocarcinoma confined to the placenta with no evidence of dissemination to the mother, or infant is the least common scenario. Case presentation The patient is an 18 year-old Gravida 1 Para 1 African American female who delivered a viable 3641 g female infant at 39 weeks gestation. Her pregnancy course was complicated by gestational hypertension during the third trimester. Her placenta revealed intraplacental choriocarcinoma. She was then followed closely by the Gynecologic Oncology service with a weekly serum beta human chorionic gonadotropin value. Beta human chorionic gonadotropin values dropped from 3070 mIU/ml to less than 2 mIU/ml two months post partum. No chemotherapy was initiated. Metastasis was ruled out by chest x-ray and whole body computed tomography scan. To date, both mother and baby are well. Conclusion Due to the potential fatal outcome of placental choriocarcinoma, careful evaluation of both mother and infant after the diagnosis is made is important. The incidence of placental choriocarcinoma may actually be higher than expected since it is not routine practice to send placentas for pathological evaluation after a normal spontaneous delivery. The obstetrician, pathologist, and pediatrician should have an increased awareness of placental choriocarcinoma and its manifestations.

  16. How Well Does LCA Model Land Use Impacts on Biodiversity?--A Comparison with Approaches from Ecology and Conservation.

    Science.gov (United States)

    Curran, Michael; de Souza, Danielle Maia; Antón, Assumpció; Teixeira, Ricardo F M; Michelsen, Ottar; Vidal-Legaz, Beatriz; Sala, Serenella; Milà i Canals, Llorenç

    2016-03-15

    The modeling of land use impacts on biodiversity is considered a priority in life cycle assessment (LCA). Many diverging approaches have been proposed in an expanding literature on the topic. The UNEP/SETAC Life Cycle Initiative is engaged in building consensus on a shared modeling framework to highlight best-practice and guide model application by practitioners. In this paper, we evaluated the performance of 31 models from both the LCA and the ecology/conservation literature (20 from LCA, 11 from non-LCA fields) according to a set of criteria reflecting (i) model completeness, (ii) biodiversity representation, (iii) impact pathway coverage, (iv) scientific quality, and (v) stakeholder acceptance. We show that LCA models tend to perform worse than those from ecology and conservation (although not significantly), implying room for improvement. We identify seven best-practice recommendations that can be implemented immediately to improve LCA models based on existing approaches in the literature. We further propose building a "consensus model" through weighted averaging of existing information, to complement future development. While our research focuses on conceptual model design, further quantitative comparison of promising models in shared case studies is an essential prerequisite for future informed model choice.

  17. How can LCA approaches contribute to improve geo-cycles management

    Science.gov (United States)

    Carreiras, M.; Ferreira, A. J. D.; Esteves, T. C. J.; Delgado, F.; Andrade, F.; Franco, J.; Pereira, C. D.

    2012-04-01

    Climate change and land use have become a major challenge for mankind and the natural environment. Greenhouse gas (GHG) emissions released into the atmosphere in ever rapidly growing volumes are most likely to be responsible for this change. Carbon dioxide gas (CO2) is suggested to be the main cause of global warming. Carbon reduction is the key to preventing this, for example, by enhancing energy efficiency and mitigating carbon emissions by means of green energy and adjusting the use of natural resources. Different activities produce distinguish impacts, and each product generates specific impacts on nature. The impact of man activities in the geo-cycles is of paramount importance in what concerns long term sustainability. Nevertheless, the environmental and sustainability impacts of different approaches and techniques of ecosystem management is a difficult question that can be assessed using LCA techniques LCA is a technique to assess environmental impacts associated with all the stages of a product's life from-cradle-to-grave. Based on that, LCA can be effective in supporting the assessment of decision making on complex sustainability issues because it can integrate the diversity of impacts categories guise and it can be adapted to a large variety of contexts. By incorporating quantitative data LCA allows decision makers to include a full range of economic, environmental, social and technical criteria. The integrated framework is configured such that the pros and cons of alternative environmental and energy strategies can be measured in terms of their ability to achieve the overall goals and objectives of the sustainable development, while satisfying the pollution control requirements. Because it is holistic, integrate and dynamic, this approach represents a state of the art tool for enhance the sustainable development of a sector, allowing a more transparent and participated management, a basic instrument for improved competitiveness. This approach may serve

  18. The incidental pulmonary nodule in a child. Part 2: Commentary and suggestions for clinical management, risk communication and prevention

    International Nuclear Information System (INIS)

    Westra, Sjirk J.; Thacker, Paul G.; Podberesky, Daniel J.; Lee, Edward Y.; Iyer, Ramesh S.; Hegde, Shilpa V.; Guillerman, R.P.; Mahani, Maryam Ghadimi

    2015-01-01

    The incidental detection of small lung nodules in children is a vexing consequence of an increased reliance on CT. We present an algorithm for the management of lung nodules detected on CT in children, based on the presence or absence of symptoms, the presence or absence of elements in the clinical history that might explain these nodules, and the imaging characteristics of the nodules (such as attenuation measurements within the nodule). We provide suggestions on how to perform a thoughtfully directed and focused search for clinically occult extrathoracic disease processes (including malignant disease) that may present as an incidentally detected lung nodule on CT. This algorithm emphasizes that because of the lack of definitive information on the natural history of small solid nodules that are truly detected incidentally, their clinical management is highly dependent on the caregivers' individual risk tolerance. In addition, we present strategies to reduce the prevalence of these incidental findings, by preventing unnecessary chest CT scans or inadvertent inclusion of portions of the lungs in scans of adjacent body parts. Application of these guidelines provides pediatric radiologists with an important opportunity to practice patient-centered and evidence-based medicine. (orig.)

  19. A Comparison between Experienced and Novice Teachers in Using Incidental Focus on Form Techniques in EFL Classrooms

    Directory of Open Access Journals (Sweden)

    Yassamin Pouriran

    2012-11-01

    Full Text Available This paper reports the findings of an empirical study that explored whether EFL teachers’ use of incidental focus-on-form techniques was influenced by their level of experience. Also, it investigated the distribution of incidental focus on form types at intermediate level and they were coded based on Lyster and Ranta (1997 and Panova and Lyster (2002 models. Incidental focus on form occurs spontaneously, without prior intention during meaning-focused activities and targets a variety of linguistic items. Here specific forms are not intentionally focused on, but are attended to spontaneously by teachers and other learners within meaning-driven contexts. Six teachers (three experienced and three novice participated in this study. The data was drawn from transcripts of oral corrective feedback moves of six intact classes which were audio and video-recorded totaling 9 hours. A descriptive design which employed qualitative and quantitative data collection procedure was adopted. The results revealed that experienced teachers used incidental focus on form techniques more frequently than novice teachers. This study supports the notion that integrative activities which can integrate a focus on form into L2 communicative activities can contribute to learning a foreign language in terms of both accuracy and fluency.

  20. Economic and environmental analysis of four different configurations of anaerobic digestion for food waste to energy conversion using LCA for: a food service provider case study.

    Science.gov (United States)

    Franchetti, Matthew

    2013-07-15

    The US disposes of more than 34 million tons of food waste in landfills per year. As this food waste decomposes it generates methane gas and negatively contributes to global warming. Diverting theses organic food wastes from landfills and to emerging technologies will prevent these wastes and greenhouse gas emissions while at the same time generating a source renewable energy by collecting the emitted gases. From a waste prevention standpoint, instead of the food waste decomposing at local landfills, it is being converted into an energy source and the by-product may be used as a fertilizer (Fine and Hadas, 2012). The purpose of this study was to compare four different configurations of anaerobic digestion of organic waste to energy technologies from an economic, energy, and emissions standpoint using LCA via a case study at a large food services provider in Northwest Ohio, USA. The technologies studied included two-stage anaerobic digestion system using ultrasound pre-treating, two stage continuous combined thermophilic acidogenic hydrogenesis and mesophilic with recirculation of the digested sludge, long-term anaerobic digestion of food waste stabilized by trace elements, and single stage anaerobic digestion. Using LCA, these scenarios were compared to landfill disposal of the food waste. The findings from the case study indicated that implementing on-site waste to energy systems will result in lower operation costs and lower environmental impacts. In addition, a standardized environmental and economic comparison of competing food waste to energy technologies is provided. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Identification and Selection of Alternative Scenarios in LCA Studies of Integrated Waste Management Systems: A Review of Main Issues and Perspectives

    Directory of Open Access Journals (Sweden)

    Andrea Raggi

    2012-09-01

    Full Text Available Life Cycle Assessment (LCA is a decision support tool that can be used to assess the environmental performance of an integrated waste management system or to identify the system with the best performance through a comparative analysis of different scenarios. The results of the analysis depend primarily on how the scenarios to be compared are defined, that is on which waste fractions are assumed to be sent to certain treatments/destinations and in what amounts. This paper reviews LCAs of integrated waste management systems with the aim of exploring how the scenarios to be compared are defined in the preliminary phase of an LCA. This critical review highlighted that various criteria, more or less subjective, are generally used for the definition of scenarios. Furthermore, the number of scenarios identified and compared is generally limited; this may entail that only the best option among a limited set of possibilities can be selected, instead of identifying the best of all possible combinations. As a result, the advisability of identifying an integrated life cycle-based methodological approach that allows finding the most environmentally sound scenario among all of those that are theoretically possible is stressed.

  2. Enabling optimization in LCA: from “ad hoc” to “structural” LCA approach—based on a biodiesel well-to-wheel case study

    DEFF Research Database (Denmark)

    Herrmann, Ivan Tengbjerg; Lundberg-Jensen, Martin; Jørgensen, Andreas

    2014-01-01

    for searching or screening product systems for environmental optimization potentials. In the presented case, the design has been a rather simple full factorial design. More complicated problems or designs, such as fractional designs, nested designs, split plot designs, and/or unbalanced data, in the context...... 2005). Through a biodiesel well-to-wheel study, we demonstrate a generic approach of applying explanatory variables and corresponding impact categories within the LCA methodology. Explanatory variables are product system variables that can influence the environmental impacts from the system....... Furthermore, using the structural approach enables two different possibilities for optimization: (1) single-objective optimization (SO) based on response surface methodology (Montgomery 2005) and (2) multiobjective optimization (MO) by the hypervolume estimation taboo search (HETS) method. HETS enables MO...

  3. Clinicoradiological studies and frequency of incidental meningiomas on brain check-up

    International Nuclear Information System (INIS)

    Ikeda, Ken; Kashihara, Hidetoshi; Hosozawa, Ken-ichi; Anan, Kozo; Tamura, Masaki; Iwamoto, Konosuke; Ito, Hirono; Kawase, Yuji; Iwasaki, Yasuo

    2008-01-01

    The purpose of this study is to evaluate clinico-radiological findings and to estimate frequency of incidental meningiomas detected by brain check-up (BC). A total of 12,258 healthy adults (8,515 men and 3,743 women) had BC, using physical check-up, brain magnetic resonance imaging (MRI) and MR angiography. Mean age (SD) was 52.6 (11.4) years, 52.7 (11.2) in men and 52.5 (11.8) in women. Duration of this study was between April 2004 and March 2007. BC subjects were divided into the first BC and the repeated BC group. The number of the first BC subjects was 5,056 (3,284 men and 1,772 women). In the repeated group defined that they had the first BC before April 2004 in our center, there were 7,202 subjects (5,231 men and 1,971 women). Fifteen subjects (7 men and 8 women) were diagnosed as meningiomas. Fourteen cases were detected by the first BC and one case by the repeated BC. The percentage of incidental meningiomas in the first BC group was calculated as 0.28, 0.18 in men and 0.45 in women. The sex ratio of women/men was 2.5. The mean age of those cases was 55.2 (10.1), 54.6 (12.9) in men and 55.8 (7.7) in women. Incidental rate of meningioma in the repeated BC group was calculated as 0.01% and 0.02% in men. No subjects had meningioma at age ≤30 years. Asymptomatic meningiomas were seen in 14 cases (93.3%) and they expected BC to ascertain healthy and normal brain by themselves. The size of tumors was ranged 10 to 46 mm and mean (SD) was 21.3 (10.2) mm. The locations of meningiomas were variable. Three cases had surgical removal. Twelve cases were under investigation on MRI. In middle-aged working subjects, incidental rates of asymptomatic meningiomas detected by BC are not uncommon in Japan. We should pay more attention to incidental meningioma when brain MRI is performed in 40-60 years women. (author)

  4. Fostering incidental experiences of nature through green infrastructure planning.

    Science.gov (United States)

    Beery, Thomas H; Raymond, Christopher M; Kyttä, Marketta; Olafsson, Anton Stahl; Plieninger, Tobias; Sandberg, Mattias; Stenseke, Marie; Tengö, Maria; Jönsson, K Ingemar

    2017-11-01

    Concern for a diminished human experience of nature and subsequent decreased human well-being is addressed via a consideration of green infrastructure's potential to facilitate unplanned or incidental nature experience. Incidental nature experience is conceptualized and illustrated in order to consider this seldom addressed aspect of human interaction with nature in green infrastructure planning. Special attention has been paid to the ability of incidental nature experience to redirect attention from a primary activity toward an unplanned focus (in this case, nature phenomena). The value of such experience for human well-being is considered. The role of green infrastructure to provide the opportunity for incidental nature experience may serve as a nudge or guide toward meaningful interaction. These ideas are explored using examples of green infrastructure design in two Nordic municipalities: Kristianstad, Sweden, and Copenhagen, Denmark. The outcome of the case study analysis coupled with the review of literature is a set of sample recommendations for how green infrastructure can be designed to support a range of incidental nature experiences with the potential to support human well-being.

  5. Incidentally Detected Enhancing Breast Lesions on Chest Computed Tomography

    International Nuclear Information System (INIS)

    Lin, Wen Chiung; Hsu, Hsian He; Yu, Jyh Cherng; Hsu, Giu Cheng; Yu, Cheng Ping; Chang, Tsun Hou; Huang, Guo Shu; Li, Chao Shiang

    2011-01-01

    To evaluate the nature and imaging appearance of incidental enhancing breast lesions detected on a routine contrast-enhanced chest CT. Twenty-three patients with incidental enhancing breast lesions on contrast-enhanced chest CT were retrospectively reviewed. The breast lesions were reviewed by unenhanced and enhanced CT, and evaluated by observing the shapes, margins, enhancement patterns and backgrounds of breast lesions. A histopathologic diagnosis or long-term follow-up served as reference standard. Sixteen (70%) patients had malignant breast lesions and seven (30%) had benign lesions. In 10 patients, the breast lesions were exclusively detected on contrast-enhanced CT. Using unenhanced CT, breast lesions with fi broglandular backgrounds were prone to be obscured (p < 0.001). Incidental primary breast cancer showed an non-significant trend of a higher percentage irregular margin (p = 0.056). All of the four incidental breast lesions with non-mass-like enhancement were proven to be malignant. Routine contrast-enhanced chest CT can reveal sufficient details to allow for the detection of unsuspected breast lesions, in which some cases may be proven as malignant. An irregular margin of incidental enhancing breast lesion can be considered a suggestive sign of malignancy

  6. Incidental Focal 18F FDG Uptake in the Prostate: Clinical Significance and Differential Diagnostic Criteria

    International Nuclear Information System (INIS)

    Cho, Suk Kyong; Choi, Joon Young; Yoo, Jang; Cheon, Miju; Lee, Ji Young; Hyun, Seung Hyup; Lee, Eun Jeong; Lee, Kyung Han; Kim, Byung Tae

    2011-01-01

    The extent and intensity of 18F FDG uptake in prostate cancer patients are known to be variable, and the clinical significance of focal 18F fluorodeoxyglucose ( 18F FDG) uptake that is incidentally found on positron emission tomography (PET) has not been established. We investigated the clinical significance of incidental focal prostate uptake of 18F FDG on PET/computed tomography (CT) and analyzed differential findings on PET/CT Between malignant and benign uptake. A total of 14,854 whole body 18F FDG PET/CT scans (4,806 that were conducted during cancer screening and 10,048 that were conducted to evaluate suspected of alleged cancer outside of the prostate) were retrospectively reviewed to determine the presence, location, multiplicity reviewed to determine the presence, location, multiplicity and maximum standardized uptake value (SUVmax) of focal prostate uptake and combined calcification. The final diagnosis determined by serum prostate specific antigen (PSA) level and biopsy was compared with PET findings. Incidental focal prostate uptake was observed in 148 of 14,854 scans (1.0%). Sixty seven of these 148 subjects who had diagnostic confirmation were selected for further analysis. Prostate cancer was diagnosed in nine of 67 subjects (13.4%). The remaining 58 subjects had no malignancy in the prostate based on normal serum PSA level (n=53), or elevated serum PSA level with a negative biopsy result (n=5). While 84.6% (11/13) of malignant uptake was peripherally located in the prostate glands, 60.2% (50/83) of benign uptake was centrally located (p 18F FDG uptake un the prostate is not common, the incidence of cancer with focal uptake is not low. Therefore, these findings deserve further evaluation. The location of the focal prostate uptake may help with the selection of high risk prostate cancer patients.

  7. Review of LCA studies of solid waste management systems – Part II: Methodological guidance for a better practice

    International Nuclear Information System (INIS)

    Laurent, Alexis; Clavreul, Julie; Bernstad, Anna; Bakas, Ioannis; Niero, Monia; Gentil, Emmanuel; Christensen, Thomas H.; Hauschild, Michael Z.

    2014-01-01

    Highlights: • We perform a critical review of 222 LCA studies of solid waste management systems. • We analyse the past LCA practice against the ISO standard and ILCD Handbook guidance. • Malpractices exist in many methodological aspects with large variations among studies. • Many of these aspects are important for the reliability of the results. • We provide detailed recommendations to practitioners of waste management LCAs. - Abstract: Life cycle assessment (LCA) is increasingly used in waste management to identify strategies that prevent or minimise negative impacts on ecosystems, human health or natural resources. However, the quality of the provided support to decision- and policy-makers is strongly dependent on a proper conduct of the LCA. How has LCA been applied until now? Are there any inconsistencies in the past practice? To answer these questions, we draw on a critical review of 222 published LCA studies of solid waste management systems. We analyse the past practice against the ISO standard requirements and the ILCD Handbook guidelines for each major step within the goal definition, scope definition, inventory analysis, impact assessment, and interpretation phases of the methodology. Results show that malpractices exist in several aspects of the LCA with large differences across studies. Examples are a frequent neglect of the goal definition, a frequent lack of transparency and precision in the definition of the scope of the study, e.g. an unclear delimitation of the system boundaries, a truncated impact coverage, difficulties in capturing influential local specificities such as representative waste compositions into the inventory, and a frequent lack of essential sensitivity and uncertainty analyses. Many of these aspects are important for the reliability of the results. For each of them, we therefore provide detailed recommendations to practitioners of waste management LCAs

  8. Review of LCA studies of solid waste management systems – Part II: Methodological guidance for a better practice

    Energy Technology Data Exchange (ETDEWEB)

    Laurent, Alexis, E-mail: alau@dtu.dk [Division for Quantitative Sustainability Assessment, Department of Management Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); Clavreul, Julie [Residual Resources Engineering, Department of Environmental Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); Bernstad, Anna [Water and Environmental Engineering, Department of Chemical Engineering, Lund University, 221 00 Lund (Sweden); Bakas, Ioannis [Division for Quantitative Sustainability Assessment, Department of Management Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); Niero, Monia [Division for Quantitative Sustainability Assessment, Department of Management Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); ECO – Ecosystems and Environmental Sustainability, Department of Chemical and Biochemical Engineering, Technical University of Denmark, 4000 Roskilde (Denmark); Gentil, Emmanuel [Copenhagen Resource Institute, 1215 Copenhagen K (Denmark); Christensen, Thomas H. [Residual Resources Engineering, Department of Environmental Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark); Hauschild, Michael Z. [Division for Quantitative Sustainability Assessment, Department of Management Engineering, Technical University of Denmark, 2800 Kgs. Lyngby (Denmark)

    2014-03-01

    Highlights: • We perform a critical review of 222 LCA studies of solid waste management systems. • We analyse the past LCA practice against the ISO standard and ILCD Handbook guidance. • Malpractices exist in many methodological aspects with large variations among studies. • Many of these aspects are important for the reliability of the results. • We provide detailed recommendations to practitioners of waste management LCAs. - Abstract: Life cycle assessment (LCA) is increasingly used in waste management to identify strategies that prevent or minimise negative impacts on ecosystems, human health or natural resources. However, the quality of the provided support to decision- and policy-makers is strongly dependent on a proper conduct of the LCA. How has LCA been applied until now? Are there any inconsistencies in the past practice? To answer these questions, we draw on a critical review of 222 published LCA studies of solid waste management systems. We analyse the past practice against the ISO standard requirements and the ILCD Handbook guidelines for each major step within the goal definition, scope definition, inventory analysis, impact assessment, and interpretation phases of the methodology. Results show that malpractices exist in several aspects of the LCA with large differences across studies. Examples are a frequent neglect of the goal definition, a frequent lack of transparency and precision in the definition of the scope of the study, e.g. an unclear delimitation of the system boundaries, a truncated impact coverage, difficulties in capturing influential local specificities such as representative waste compositions into the inventory, and a frequent lack of essential sensitivity and uncertainty analyses. Many of these aspects are important for the reliability of the results. For each of them, we therefore provide detailed recommendations to practitioners of waste management LCAs.

  9. Environmental impacts of irrigated and rain-fed barley production in Iran using life cycle assessment (LCA)

    Energy Technology Data Exchange (ETDEWEB)

    Houshyar, E.

    2017-07-01

    Current intensive grain crops production is often associated with environmental burdens. However, very few studies deal with the environmental performance of both current and alternative systems of barley production. This study was undertaken to evaluate energy consumption and environmental impacts of irrigated and rain-fed barley production. Additionally, three alternative scenarios were examined for irrigated barley fields including conservation tillage and biomass utilization policies. The findings showed that around 25 GJ/ha energy is needed in order to produce 2300 kg/ha irrigated barley and 13 GJ/ha for 1100 kg/ha rain-fed barley. Life cycle assessment (LCA) results indicated that irrigated farms had more environmental impacts than rain-fed farms. Electricity generation and consumption had the highest effect on the abiotic depletion potential, human toxicity potential, freshwater and marine aquatic ecotoxicity potential. However, alternative scenarios revealed that using soil conservation tillage systems and biomass consumption vs. gas for electricity generation at power plants can significantly mitigate environmental impacts of irrigated barley production similar to the rain-fed conditions while higher yield is obtained.

  10. Environmental impacts of irrigated and rain-fed barley production in Iran using life cycle assessment (LCA)

    International Nuclear Information System (INIS)

    Houshyar, E.

    2017-01-01

    Current intensive grain crops production is often associated with environmental burdens. However, very few studies deal with the environmental performance of both current and alternative systems of barley production. This study was undertaken to evaluate energy consumption and environmental impacts of irrigated and rain-fed barley production. Additionally, three alternative scenarios were examined for irrigated barley fields including conservation tillage and biomass utilization policies. The findings showed that around 25 GJ/ha energy is needed in order to produce 2300 kg/ha irrigated barley and 13 GJ/ha for 1100 kg/ha rain-fed barley. Life cycle assessment (LCA) results indicated that irrigated farms had more environmental impacts than rain-fed farms. Electricity generation and consumption had the highest effect on the abiotic depletion potential, human toxicity potential, freshwater and marine aquatic ecotoxicity potential. However, alternative scenarios revealed that using soil conservation tillage systems and biomass consumption vs. gas for electricity generation at power plants can significantly mitigate environmental impacts of irrigated barley production similar to the rain-fed conditions while higher yield is obtained.

  11. [A Case of Rectal Syphilis Incidentally Found at Regular Medical Check-up].

    Science.gov (United States)

    You, Ji Hong; Cho, Ki Won; Cha, Yoon Jin; Park, Hyo Jin

    2016-10-25

    Syphilis is a rare disease in the rectum. It is difficult to diagnose because the characteristics of the rectal syphilis rectal lesion are highly varied. The endoscopic findings of rectal syphilis are proctitis, ulcers, and masses. If rectal syphilis is suspected to be the cause for rectal lesions, it is important for physicians to consider the sexual history and sexual orientation of the patient. We report a case of incidental rectal syphilis in a 41-year-old man diagnosed during a regular medical check-up.

  12. LCA of greywater management within a water circular economy restorative thinking framework.

    Science.gov (United States)

    Dominguez, Sara; Laso, Jara; Margallo, María; Aldaco, Rubén; Rivero, Maria J; Irabien, Ángel; Ortiz, Inmaculada

    2018-04-15

    Greywater reuse is an attractive option for the sustainable management of water under water scarcity circumstances, within a water circular economy restorative thinking framework. Its successful deployment relies on the availability of low cost and environmentally friendly technologies. The life cycle assessment (LCA) approach provides the appropriate methodological tool for the evaluation of alternative treatments based on environmental decision criteria and, therefore, it is highly useful during the process conceptual design. This methodology should be employed in the early design phase to select those technologies with lower environmental impact. This work reports the comparative LCA of three scenarios for greywater reuse: photocatalysis, photovoltaic solar-driven photocatalysis and membrane biological reactor, in order to help the selection of the most environmentally friendly technology. The study has been focused on the removal of the surfactant sodium dodecylbenzenesulfonate, which is used in the formulation of detergents and personal care products and, thus, widely present in greywater. LCA was applied using the Environmental Sustainability Assessment methodology to obtain two main environmental indicators in order to simplify the decision making process: natural resources and environmental burdens. Energy consumption is the main contributor to both indicators owing to the high energy consumption of the light source for the photocatalytic greywater treatment. In order to reduce its environmental burdens, the most desirable scenario would be the use of solar light for the photocatalytic transformation. However, while the technological challenge of direct use of solar light is approached, the environmental suitability of the photovoltaic solar energy driven photocatalysis technology to greywater reuse has been demonstrated, as it involves the smallest environmental impact among the three studied alternatives. Copyright © 2017 Elsevier B.V. All rights

  13. Simplified LCA and matrix methods in identifying the environmental aspects of a product system.

    Science.gov (United States)

    Hur, Tak; Lee, Jiyong; Ryu, Jiyeon; Kwon, Eunsun

    2005-05-01

    In order to effectively integrate environmental attributes into the product design and development processes, it is crucial to identify the significant environmental aspects related to a product system within a relatively short period of time. In this study, the usefulness of life cycle assessment (LCA) and a matrix method as tools for identifying the key environmental issues of a product system were examined. For this, a simplified LCA (SLCA) method that can be applied to Electrical and Electronic Equipment (EEE) was developed to efficiently identify their significant environmental aspects for eco-design, since a full scale LCA study is usually very detailed, expensive and time-consuming. The environmentally responsible product assessment (ERPA) method, which is one of the matrix methods, was also analyzed. Then, the usefulness of each method in eco-design processes was evaluated and compared using the case studies of the cellular phone and vacuum cleaner systems. It was found that the SLCA and the ERPA methods provided different information but they complemented each other to some extent. The SLCA method generated more information on the inherent environmental characteristics of a product system so that it might be useful for new design/eco-innovation when developing a completely new product or method where environmental considerations play a major role from the beginning. On the other hand, the ERPA method gave more information on the potential for improving a product so that it could be effectively used in eco-redesign which intends to alleviate environmental impacts of an existing product or process.

  14. Comparing LCC with LCA to assess PSS sustainability: the case of the eco-box

    DEFF Research Database (Denmark)

    Chong, K.N.; Dreijer, L.S.; Howard, Thomas J.

    2014-01-01

    Product/Service-Systems strategies are increasingly proving to be a source of competitive advantage and environmental improvement for engineering companies, the main hypothesis being that PSS should allow to decouple functionality, user satisfaction and financial income on the one hand, from the ...... the total environmental impact of the function-delivering technology on the other. This paper describes an integration of Life Cycle Assessment (LCA) and Life Cycle Costing (LCC), in an attempt to see if the two life cycle elements are related....

  15. EcoDesign and LCA approach toward sustainable micro products development

    DEFF Research Database (Denmark)

    De Grave, Arnaud; Olsen, Stig Irving; Hansen, Hans Nørgaard

    2009-01-01

    importance in the design of micro/nano products and of downscaled production pathways. In addition, the topic of EcoDesign, which has been used for a long time now in so-called “macro size”, is explained and the panel of tools used for designing products taking care of the environment will be investigated...... in the context of micro technology. Ecodesign and LCA take into account environmental impact of production of micro and nano products, but another important issue to include is the impact of such applications on human health. A particular focus has been put on the human health risks of nanoparticles....

  16. LCA of pork products & evaluation of alternative super-chilling techniques

    DEFF Research Database (Denmark)

    Bonou, Alexandra; Birkved, Morten

    after cooling technologies, which affect the products’ shelf life: The purpose is to identify the technology leading to least environmental impacts in a life cycle perspective; also to facilitate a benchmarking of these technologies relative to existing after-cooling approaches i.e. freezing.......This LCA study has two aims: 1) The environmental assessment of Danish pork products (Danish Landrace breed): The purpose is to put the pork production system into perspective and to identify the relative contribution of different life cycle stages; 2) The comparative assessment of alternative...

  17. Characterisation of social impacts in LCA. Part 2: implementation in six company case studies

    DEFF Research Database (Denmark)

    Dreyer, Louise Camilla; Hauschild, Michael Zwicky; Schierbeck, Jens

    2010-01-01

    , Restrictions of freedom of association and collective bargaining, and Child labour (Dreyer et al, 2009a). These impact categories are considered by the authors to be among the obligatory impact categories in a Social LCA. The characterisation models combine information about the way a company manages its...... or industrial branch or sector) of the company. The resulting indicator score represents the risk that violations take place of the labour right represented by the impact category. Results The social impact characterisation is performed for each of the six case studies using the methodology earlier developed...

  18. Environmental assessment of solid waste landfilling technologies by means of LCA-modeling.

    Science.gov (United States)

    Manfredi, Simone; Christensen, Thomas H

    2009-01-01

    By using life cycle assessment (LCA) modeling, this paper compares the environmental performance of six landfilling technologies (open dump, conventional landfill with flares, conventional landfill with energy recovery, standard bioreactor landfill, flushing bioreactor landfill and semi-aerobic landfill) and assesses the influence of the active operations practiced on these performances. The environmental assessments have been performed by means of the LCA-based tool EASEWASTE, whereby the functional unit utilized for the LCA is "landfilling of 1ton of wet household waste in a 10m deep landfill for 100 years". The assessment criteria include standard categories (global warming, nutrient enrichment, ozone depletion, photo-chemical ozone formation and acidification), toxicity-related categories (human toxicity and ecotoxicity) and impact on spoiled groundwater resources. Results demonstrate that it is crucially important to ensure the highest collection efficiency of landfill gas and leachate since a poor capture compromises the overall environmental performance. Once gas and leachate are collected and treated, the potential impacts in the standard environmental categories and on spoiled groundwater resources significantly decrease, although at the same time specific emissions from gas treatment lead to increased impact potentials in the toxicity-related categories. Gas utilization for energy recovery leads to saved emissions and avoided impact potentials in several environmental categories. Measures should be taken to prevent leachate infiltration to groundwater and it is essential to collect and treat the generated leachate. The bioreactor technologies recirculate the collected leachate to enhance the waste degradation process. This allows the gas collection period to be reduced from 40 to 15 years, although it does not lead to noticeable environmental benefits when considering a 100 years LCA-perspective. In order to more comprehensively understand the influence

  19. Climate change damage functions in LCA – (1) from global warming potential to natural environment damages

    DEFF Research Database (Denmark)

    Callesen, Ingeborg; Hauschild, Michael Zwicky; Bagger Jørgensen, Rikke

    Energy use often is the most significant contributor to the impact category ‘global warming’ in life cycle impact assessment. However, the potential global warming effects on the climate at regional level and consequential effects on the natural environment are not thoroughly described within LCA...... methodology. The current scientific understanding of the extent of climate change impacts is limited due to the immense complexity of the multi-factorial environmental changes and unknown adaptive capacities at process, species and ecosystem level. In the presentation we argue that the global warming impacts...

  20. Investor Outlook: Focus on Upcoming LCA2 Gene Therapy Phase III Results.

    Science.gov (United States)

    Schimmer, Joshua; Breazzano, Steven

    2015-09-01

    Investor interest in gene therapy has increased substantially over the past few years, and the next major catalyst for the field is likely to be Spark Therapeutics's phase III trial for the treatment of visual impairment caused by RPE65 gene mutations (often referred to as Leber congenital amaurosis type 2, or LCA2, but may include other retinal disorders). Analysis of the approach from the basic genetics, underlying visual mechanisms, clinical data, and commercialization considerations helps frame investor expectations and the potential implications for the broader field.

  1. Preparing the ground for an operational handling of long-term emissions in LCA

    DEFF Research Database (Denmark)

    Bakas, Ioannis; Hauschild, Michael Zwicky; Astrup, Thomas Fruergaard

    2015-01-01

    Currently, there is no meaningful methodology for the estimation of environmental impacts from long-term heavy metal emissions in a life cycle assessment (LCA) context, when an assessment of landfill and mining technologies is performed. In this paper, the aims are to investigate the main issues...... and their differences are highlighted.A suitable dynamic LCI is identified for landfill emissions, which calculates Ni, Zn, Cd and Pb emissions as a function of time, based on assumed developments of the leachate pH. The results of the application of the different impact assessment methods on that LCI differ by up to 8...

  2. Life Cycle Thinking and the Use of LCA in Policies Around the World

    DEFF Research Database (Denmark)

    Sonnemann, G.; Gemechu, E. D.; Sala, S.

    2018-01-01

    relevant for policies focusing on design for sustainability, sustainable consumer information, sustainable procurement and waste management, minimization and prevention as well as sector-specific policies like sustainable energy and food supply. Examples of life cycle thinking and the use of LCA...... is the 10-Year Framework of Programmes on SCP adopted in 2012 and the global agreements on the Sustainable Development Goals (SDGs) adopted in 2015. Life cycle thinking has become mature, moving from its academic origins and limited uses, primarily in-house in large companies, to more powerful approaches...

  3. BayesLCA: An R Package for Bayesian Latent Class Analysis

    Directory of Open Access Journals (Sweden)

    Arthur White

    2014-11-01

    Full Text Available The BayesLCA package for R provides tools for performing latent class analysis within a Bayesian setting. Three methods for fitting the model are provided, incorporating an expectation-maximization algorithm, Gibbs sampling and a variational Bayes approximation. The article briefly outlines the methodology behind each of these techniques and discusses some of the technical difficulties associated with them. Methods to remedy these problems are also described. Visualization methods for each of these techniques are included, as well as criteria to aid model selection.

  4. Education and training in LCA and life-cycle thinking experience and needs

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard; Bey, Niki; Hauschild, Michael Zwicky

    2003-01-01

    . The target group for the educational offers are students of both short and long term higher education, primarily engineering students of various disciplines. However, teaching within LCA and life cycle thinking also takes place in curricula for designers, architects and production technicians. The target...... group for the training are in most cases companies, and participants are in mostly employees from the environmental department, but there are also offers for governmental authorities and unemployed. Both education and further training mainly convey qualifications on a "knowing about"-level in the form...

  5. Defining incidental perineural invasion: the need for a national registry.

    Science.gov (United States)

    Buchanan, Lauren; De'Ambrosis, Brian; DeAmbrosis, Kathryn; Warren, Timothy; Huilgol, Shyamala; Soyer, H Peter; Panizza, Benedict

    2014-05-01

    This article by the Perineural Invasion (PNI) Registry Group aims to clarify clinical and histopathological ambiguities surrounding PNI in non-melanoma skin cancer (NMSC). PNI is reportedly present in approximately 2-6% of cases of NMSC and is associated with greater rates of morbidity and mortality. The distinction between clinical PNI and incidental PNI is somewhat unclear, especially in regard to management and prognosis. One important objective of the PNI Registry is to develop a standardised method of classifying perineural invasion. Hence, in this article we propose a definition for PNI and for its sub-classification. This article also provides a critical analysis of the current literature on the treatment of incidental PNI by evaluating the key cohort studies that have investigated the use of surgery or radiotherapy in the management of incidental PNI. At present, there are no universal clinical guidelines that specify the acceptable treatment of NMSC exhibiting incidental PNI. Consequently, patients often receive surgery with varying wider margins, or radiotherapy despite the limited evidence substantiating such management options. It is evident from the existing literature that current opinion is divided over the benefit of adjuvant radiotherapy. Certain prognostic factors have been proposed, such as the size and depth of tumour invasion, nerve diameter, the presence of multifocal PNI and the type of tumour. The PNI Registry is a web-based registry that has been developed to assist in attaining further data pertaining to incidental PNI in NMSC. It is envisaged that this information will provide the foundation for identifying and defining best practice in managing incidental PNI. © 2013 The Australasian College of Dermatologists.

  6. Fostering incidental experiences of nature through green infrastructure planning

    DEFF Research Database (Denmark)

    Beery, Thomas H; Raymond, Christopher M; Kyttä, Marketta

    2017-01-01

    of such experience for human well-being is considered. The role of green infrastructure to provide the opportunity for incidental nature experience may serve as a nudge or guide toward meaningful interaction. These ideas are explored using examples of green infrastructure design in two Nordic municipalities...... to consider this seldom addressed aspect of human interaction with nature in green infrastructure planning. Special attention has been paid to the ability of incidental nature experience to redirect attention from a primary activity toward an unplanned focus (in this case, nature phenomena). The value...

  7. Partial spline score test to determine if tumors are incidental

    International Nuclear Information System (INIS)

    Griffith, W.C.

    1994-01-01

    A primary consideration in many rodent bioassays is whether a tumor observed in an animal has affected its life span. When tumors are incidental, the natural death times can be regarded as random sampling times unrelated to the presence of the tumor. In this case, animals dying from natural causes and those sacrificed can be combined to estimate the prevalence p(t) of the tumors in the living animals. When tumors are incidental, the tumor incidence rate, λ T (t), is related to the prevalence by λ T (t) = p(t) 1 - p(t) , where p(t) is the derivative of the prevalence

  8. Review of LCA studies of solid waste management systems--part II: methodological guidance for a better practice.

    Science.gov (United States)

    Laurent, Alexis; Clavreul, Julie; Bernstad, Anna; Bakas, Ioannis; Niero, Monia; Gentil, Emmanuel; Christensen, Thomas H; Hauschild, Michael Z

    2014-03-01

    Life cycle assessment (LCA) is increasingly used in waste management to identify strategies that prevent or minimise negative impacts on ecosystems, human health or natural resources. However, the quality of the provided support to decision- and policy-makers is strongly dependent on a proper conduct of the LCA. How has LCA been applied until now? Are there any inconsistencies in the past practice? To answer these questions, we draw on a critical review of 222 published LCA studies of solid waste management systems. We analyse the past practice against the ISO standard requirements and the ILCD Handbook guidelines for each major step within the goal definition, scope definition, inventory analysis, impact assessment, and interpretation phases of the methodology. Results show that malpractices exist in several aspects of the LCA with large differences across studies. Examples are a frequent neglect of the goal definition, a frequent lack of transparency and precision in the definition of the scope of the study, e.g. an unclear delimitation of the system boundaries, a truncated impact coverage, difficulties in capturing influential local specificities such as representative waste compositions into the inventory, and a frequent lack of essential sensitivity and uncertainty analyses. Many of these aspects are important for the reliability of the results. For each of them, we therefore provide detailed recommendations to practitioners of waste management LCAs. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. 131I-6β-iodomethyl-19-norcholesterol scintigraphy in a patient with incidentally discovered adrenal tuberculosis

    International Nuclear Information System (INIS)

    Bardet, S.; Mallmann, V. de; Dupas, B.; Peltier, P.; Deumier, B.

    1994-01-01

    Adrenal tuberculosis is rare and usually diagnosed on clinical signs of adrenal deficiency. We report here the uncommon incidental finding of an adrenal tuberculosis which was investigated in this context by radionuclide imaging with 131 I-6β-iodomethyl-19-norcholesterol. Absence of adrenal uptake which has not yet been reported is discussed in terms of differential diagnosis with the CT scan results. (authors). 10 refs., 2 figs

  10. 50 CFR 216.107 - Incidental harassment authorization for Arctic waters.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Incidental harassment authorization for Arctic waters. 216.107 Section 216.107 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL... Incidental to Specified Activities § 216.107 Incidental harassment authorization for Arctic waters. (a...

  11. 77 FR 31062 - Programs To Reduce Incidental Capture of Sea Turtles in Shrimp Fisheries; Certifications Pursuant...

    Science.gov (United States)

    2012-05-24

    ... DEPARTMENT OF STATE [Public Notice 7894] Programs To Reduce Incidental Capture of Sea Turtles in... programs to reduce the incidental capture of sea turtles in their shrimp fisheries comparable to the... other countries and one economy do not pose a threat of the incidental taking of sea turtles protected...

  12. A Review of Effect of Different Tasks on Incidental Vocabulary Acquisition

    Science.gov (United States)

    Liu, Chen L.

    2015-01-01

    Studies of incidental vocabulary acquisition in second language learning have got more and more attention both at home and abroad. By first introducing the definition and theoretical foundations of incidental vocabulary acquisition, this paper reviews empirical studies of effect of different tasks on incidental vocabulary acquisition and points…

  13. assessment of environmental impacts in comfortable furniture production process using life cycle assessment (LCA technique

    Directory of Open Access Journals (Sweden)

    hejhar abbasi

    2016-12-01

    Full Text Available Furniture industry releases annually a large amount of volatile organic compound to the environment due to the use of adhesives, textiles, paints and coating materials. There are some different methods to measure the load of pollutions and the environmental impacts. Life cycle assessment (LCA is one of the best techniques. LCA is a technique in which all environmental impacts related to a product assessed all over its life cycle, from cradle to grave, and ultimately can be used to improve the production process and to prevent unsuitable environmental impacts. In summary, it can be concluded that the use of this technique is the basis for sustainable development and improving social, economic, and environmental indices. This study focused on the collecting of a comprehensive life cycle inventory data for comfortable furniture in two different production processes (B1 and B2 located in Tehran province, and analyzed the environmental impacts during the production process as gate to gate investigation. The results revealed that emissions in production process B1 were higher than that of production process B2. The reason for this is that basic operations such as sawing and frame assembling along with final operation have been done in the same unit for case B1. Textile production and usage, and polyurethane foam were identified as the main hotspots, respectively. Moreover, the results showed that comfortable furniture production process has the highest effects on ecosystem quality, human health, and resources (fossil fuels and mines, respectively.

  14. LCA of domestic and centralized biomass combustion: The case of Lombardy (Italy)

    International Nuclear Information System (INIS)

    Caserini, S.; Livio, S.; Giugliano, M.; Grosso, M.; Rigamonti, L.

    2010-01-01

    This paper analyzes and compares the environmental impacts of biomass combustion in small appliances such as domestic open fireplaces and stoves, and in two types of centralized combined heat and power plants, feeding district heating networks. The analysis is carried out following a Life Cycle Assessment (LCA) approach. The expected savings of GHG (greenhouse gases) emissions due to the substitution of fossil fuels with biomass are quantified, as well as emissions of toxic pollutants and substances responsible for acidification and ozone formation. The LCA results show net savings of GHG emissions when using biomass instead of conventional fuels, varying from 0.08 to 1.08 t of CO 2 eq. per t of dry biomass in the different scenarios. Avoided GHG emissions thanks to biomass combustion in Lombardy are 1.32 Mt year -1 (1.5% of total regional GHG emissions). For the other impact categories, the use of biomass in district heating systems can again cause a consistent reduction of impacts, whereas biomass combustion in residential devices shows higher impacts than fossil fuels with a particular concern for PAH, VOC and particulate matter emissions. For example, in Lombardy, PM10 emissions from domestic devices are about 8100 t year -1 , corresponding to almost one third of the total particulate emissions in 2005. (author)

  15. Case Study: LCA Methodology Applied to Materials Management in a Brazilian Residential Construction Site

    Directory of Open Access Journals (Sweden)

    João de Lassio

    2016-01-01

    Full Text Available The construction industry is increasingly concerned with improving the social, economic, and environmental indicators of sustainability. More than ever, the growing demand for construction materials reflects increased consumption of raw materials and energy, particularly during the phases of extraction, processing, and transportation of materials. This work aims to help decision-makers and to promote life cycle thinking in the construction industry. For this purpose, the life cycle assessment (LCA methodology was chosen to analyze the environmental impacts of building materials used in the construction of a residence project in São Gonçalo, Rio de Janeiro, Brazil. The LCA methodology, based on ISO 14040 and ISO 14044 guidelines, is applied with available databases and the SimaPro program. As a result, this work shows that there is a substantial waste of nonrenewable energy, increasing global warming and harm to human health in this type of construction. This study also points out that, for this type of Brazilian construction, ceramic materials account for a high percentage of the mass of a total building and are thus responsible for the majority of environmental impacts.

  16. Comparative LCA of methanol-fuelled SOFCs as auxiliary power systems on-board ships

    International Nuclear Information System (INIS)

    Strazza, C.; Del Borghi, A.; Costamagna, P.; Traverso, A.; Santin, M.

    2010-01-01

    Fuel cells own the potential for significant environmental improvements both in terms of air quality and climate protection. Through the use of renewable primary energies, local pollutant and greenhouse gas emissions can be significantly minimized over the full life cycle of the electricity generation process, so that marine industry accounts renewable energy as its future energy source. The aim of this paper is to evaluate the use of methanol in Solid Oxide Fuel Cells (SOFC), as auxiliary power systems for commercial vessels, through Life Cycle Assessment (LCA). The LCA methodology allows the assessment of the potential environmental impact along the whole life cycle of the process. The unit considered is a 20 kWel fuel cell system. In a first part of the study different fuel options have been compared (methanol, bio-methanol, natural gas, hydrogen from cracking, electrolysis and reforming), then the operation of the cell fed with methanol has been compared with the traditional auxiliary power system, i.e. a diesel engine. The environmental benefits of the use of fuel cells have been assessed considering different impact categories. The results of the analysis show that fuel production phase has a strong influence on the life cycle impacts and highlight that feeding with bio-methanol represents a highly attractive solution from a life cycle point of view. The comparison with the conventional auxiliary power system shows extremely lower impacts for SOFCs.

  17. The use of LCA for modelling sustainability and environmental impact of manufacturing processes

    Energy Technology Data Exchange (ETDEWEB)

    Culaba, A; Purvis, M [Portsmouth Univ. (United Kingdom). Dept. of Mechanical and Manufacturing Engineering

    1996-12-31

    Most industries rely significantly on natural resources for raw materials and energy requirements. As a consequence of manufacturing activities, various pollutants are generated in the process. While effects on the environment can be detrimental, wastes and emissions account for a high percentage loss in the overall material balance. Unless these unnecessary losses are minimized and recovered, the environment would continue to be disadvantaged and long-term supply of raw materials and energy would likewise be affected. The key to the analysis of such problems concerns generalised procedures for the modelling of the sustainable use of resources in manufacturing processes and the development of associated sustainability criteria. This requires identifying the various aspects of manufacturing from the time the raw materials are extracted until they have been processed into products and then used or consumed and finally disposed of. The use of life cycle assessment (LCA) methodology encompasses these analyses and that of the identification of environmental effects associated with every stage of the manufacturing process. The presentation concludes that LCA is a very useful and effective tool in providing planners, legislator and decision-makers with the necessary information on the probable impacts of manufacture on the environment as well as underlying legislation, ecological, health standards and emission limits. (author)

  18. The use of LCA for modelling sustainability and environmental impact of manufacturing processes

    Energy Technology Data Exchange (ETDEWEB)

    Culaba, A.; Purvis, M. [Portsmouth Univ. (United Kingdom). Dept. of Mechanical and Manufacturing Engineering

    1995-12-31

    Most industries rely significantly on natural resources for raw materials and energy requirements. As a consequence of manufacturing activities, various pollutants are generated in the process. While effects on the environment can be detrimental, wastes and emissions account for a high percentage loss in the overall material balance. Unless these unnecessary losses are minimized and recovered, the environment would continue to be disadvantaged and long-term supply of raw materials and energy would likewise be affected. The key to the analysis of such problems concerns generalised procedures for the modelling of the sustainable use of resources in manufacturing processes and the development of associated sustainability criteria. This requires identifying the various aspects of manufacturing from the time the raw materials are extracted until they have been processed into products and then used or consumed and finally disposed of. The use of life cycle assessment (LCA) methodology encompasses these analyses and that of the identification of environmental effects associated with every stage of the manufacturing process. The presentation concludes that LCA is a very useful and effective tool in providing planners, legislator and decision-makers with the necessary information on the probable impacts of manufacture on the environment as well as underlying legislation, ecological, health standards and emission limits. (author)

  19. Eco-efficient waste glass recycling: Integrated waste management and green product development through LCA.

    Science.gov (United States)

    Blengini, Gian Andrea; Busto, Mirko; Fantoni, Moris; Fino, Debora

    2012-05-01

    As part of the EU Life + NOVEDI project, a new eco-efficient recycling route has been implemented to maximise resources and energy recovery from post-consumer waste glass, through integrated waste management and industrial production. Life cycle assessment (LCA) has been used to identify engineering solutions to sustainability during the development of green building products. The new process and the related LCA are framed within a meaningful case of industrial symbiosis, where multiple waste streams are utilised in a multi-output industrial process. The input is a mix of rejected waste glass from conventional container glass recycling and waste special glass such as monitor glass, bulbs and glass fibres. The green building product is a recycled foam glass (RFG) to be used in high efficiency thermally insulating and lightweight concrete. The environmental gains have been contrasted against induced impacts and improvements have been proposed. Recovered co-products, such as glass fragments/powders, plastics and metals, correspond to environmental gains that are higher than those related to landfill avoidance, whereas the latter is cancelled due to increased transportation distances. In accordance to an eco-efficiency principle, it has been highlighted that recourse to highly energy intensive recycling should be limited to waste that cannot be closed-loop recycled. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Assessing sustainability of a low-input single-farm vegetable box-scheme using emergy and LCA methodology

    DEFF Research Database (Denmark)

    Markussen, Mads Ville; Kulak, M.; Østergård, Hanne

    2012-01-01

    for minimizing resource use are fuels and electricity. Substitution of these would require the use of renewable energy. However, an increase in inputs from society may imply a lower net-yield to society from the farm and would thus be less desirable. The LCA data are currently being analysed and these results......Sustainable development implies necessarily making use of renewable resources to a larger extent. Thus a sustainability assessment has to identify hotspots for reducing use of non-renewable resources and potentials for substitution of these with renewable resources. LCA as well as emergy assessment......, the emergy method lacks some of the standardization and robustness of LCA. In this study we apply both methods to the same case study. The case considered is an organic stockless vegetable farm of 7 ha in UK which distributes its products in weekly boxes to 250 local consumers. The farm has systematically...

  1. Texture and flavour memory in foods : an incidental learning experiment

    NARCIS (Netherlands)

    Mojet, J.; Koster, E.P.

    2002-01-01

    Memory plays a major role in the formation of food expectations. How accessible and how accurate is incidentally acquired and stored product information? In the present experiment the memory for variations in texture (and flavour) was tested with a new and ecologically valid method. Subjects (N=69:

  2. Preliminary Assessment of Cetacean Incidental Mortality in Artisanal ...

    African Journals Online (AJOL)

    Three dolphin species and humpback whales were reported accidentally caught in fishing gear meant to catch sharks. Dolphins were mostly reported as to be entangled in gillnets; conversely longlines were only described to incidentally catch humpback whales. Bottlenose and spinner dolphins were respectively 48.10% ...

  3. Texture and flavour memory in foods : an incidental learning experiment

    NARCIS (Netherlands)

    Mojet, J.; Köster, E.P.

    2002-01-01

    Memory plays a major role in the formation of food expectations. How accessible and how accurate is incidentally acquired and stored product information? In the present experiment the memory for variations in texture (and flavour) was tested with a new and ecologically valid method. Subjects (N =

  4. Incidental right Bochdalek hernia with interruption of the inferior ...

    African Journals Online (AJOL)

    2014-05-30

    May 30, 2014 ... Case Report doi:10.4102/sajr.v18i1.592 http://sajr.org.za. Incidental right Bochdalek hernia with interruption of the inferior vena cava and hepatic venous collateral continuation: A case report. Authors: Farzanah I. Ismail1. Rule Human2. Anith Chacko1. Parmanand Naran2. Samia Ahmad1. Siraj Ellemdin2.

  5. Guidance of Spatial Attention by Incidental Learning and Endogenous Cuing

    Science.gov (United States)

    Jiang, Yuhong V.; Swallow, Khena M.; Rosenbaum, Gail M.

    2013-01-01

    Our visual system is highly sensitive to regularities in the environment. Locations that were important in one's previous experience are often prioritized during search, even though observers may not be aware of the learning. In this study we characterized the guidance of spatial attention by incidental learning of a target's spatial probability,…

  6. Implicit and Explicit Cognitive Processes in Incidental Vocabulary Acquisition

    Science.gov (United States)

    Ender, Andrea

    2016-01-01

    Studies on vocabulary acquisition in second language learning have revealed that a large amount of vocabulary is learned without an overt intention, in other words, incidentally. This article investigates the relevance of different lexical processing strategies for vocabulary acquisition when reading a text for comprehension among 24 advanced…

  7. Is Incidental Vocabulary Acquisition Feasible to EFL Learning?

    Science.gov (United States)

    Luo, Jian-ping

    2013-01-01

    For learning English as a foreign language, the efficiency of the approach of incidental vocabulary acquisition depends on the word frequency and text coverage. However, the statistics of English corpus reveals that English is a language that has a large vocabulary size but a low word frequency as well as text coverage, which is obviously not in…

  8. Task type and incidental L2 vocabulary learning: Repetition versus ...

    African Journals Online (AJOL)

    This study investigated the effect of task type on incidental L2 vocabulary learning. The different tasks investigated in this study differed in terms of repetition of encounters and task involvement load. In a within-subjects design, 72 Iranian learners of English practised 18 target words in three exercise conditions: three ...

  9. Positron emission tomography of incidentally detected small pulmonary nodules

    DEFF Research Database (Denmark)

    Fischer, B M; Mortensen, J; Dirksen, A

    2004-01-01

    The aim of this study was to assess the value of fluorodeoxyglucose positron emission tomography (FDG PET) imaging of small pulmonary nodules incidentally detected by spiral computed tomography (CT) in a high-risk population. Ten patients (five females, five males, aged 54-72 years) were recruited...

  10. Asymptomatic renal cell carcinoma incidentally detected by abdominal CT

    International Nuclear Information System (INIS)

    Yoneda, Fumio; Miyake, Noriaki; Tsujimura, Haruhiro; Nakajima, Mikio; Akiyama, Hajime

    1987-01-01

    Four cases of renal cell carcinoma that were incidentally detected by abdominal CT are reported. Abdominal CT was performed during gastro-intestinal examination in two patients and for suspected liver disease in the other two. No patient had symptoms of renal cell carcinoma, or hematuria. In all cases, the histopathological diagnosis was renal cell carcinoma of a low stage. (author)

  11. Spatial Contiguity and Incidental Learning in Multimedia Environments

    Science.gov (United States)

    Paek, Seungoh; Hoffman, Daniel L.; Saravanos, Antonios

    2017-01-01

    Drawing on dual-process theories of cognitive function, the degree to which spatial contiguity influences incidental learning outcomes was examined. It was hypothesized that spatial contiguity would mediate what was learned even in the absence of an explicit learning goal. To test this hypothesis, 149 adults completed a multimedia-related task…

  12. Historical harvest and incidental capture of fishers in California

    Science.gov (United States)

    Jeffrey C. Lewis; William J. Zielinski

    1996-01-01

    Recent petitions to list the fisher (Martes pennanti) under the Endangered Species Act have brought attention to fisher conservation. Although commercial trapping of fishers in California ended in 1946, summarizing the commercial harvest data can provide a historical perspective to fisher conservation and may indicate the prevalence of incidental...

  13. Assessment of global environmental impacts by utilizing methodology of LCA on solar water heater for dwellings; LCA shuho ni yoru taiyonetsu onsuiki no kankyo fuka hyoka

    Energy Technology Data Exchange (ETDEWEB)

    Kamoshida, J [Shibaura Institute of Technology, Tokyo (Japan); Asai, S [Yazaki Corp., Tokyo (Japan)

    1997-11-25

    CO2 emission was quantified through the life cycle of a solar water heater to assess its environment impact. Although LCA (life cycle assessment) originally sums up I/O of all materials and energy through the whole life cycle of a product to examine environment impact, this assessment was carried out for only CO2. Calculation of CO2 emission assumed a natural circulating solar water heater of 200 l in effective hot water capacity, 2.78m{sup 2} in effective collecting area, and 0.5 in average annual collecting efficiency of total solar radiation, and an auxiliary city gas heat source for compensating insufficient heat quantity. The total CO2 emission in the life cycle of a solar water heater was obtained from an industrial association table assuming the life cycles of 10 and 20 years. CO2 emission was estimated to be 5407.1kg-CO2 and 10665.2kg-CO2 for 10 and 20 years, respectively. CO2 emission due to city gas was largest in the total CO2 emission in the life cycle. As a result, for reduction of CO2 emission due to a solar water heater, improvement of equipment efficiency was most important. 6 refs., 5 figs., 3 tabs.

  14. Skin cancer of the head and neck with incidental microscopic perineural invasion

    International Nuclear Information System (INIS)

    McCord, Mark W.; Mendenhall, William M.; Parsons, James T.; Flowers, Franklin P.

    1999-01-01

    Purpose: To address outcomes in clinically asymptomatic patients in whom the unexpected finding of microscopic perineural invasion is noted at the time of surgery. Methods and Materials: The 35 patients included in this study had skin cancers of the head and neck treated with curative intent between January 1965 and April 1995 at the University of Florida. All patients were without clinical or radiographic evidence of perineural invasion but, at the time of biopsy or surgical excision, had the incidental finding of microscopic perineural invasion. Definitive therapy consisted of radiotherapy alone after lesion biopsy (3 patients) or surgical excision preceded (2 patients) or followed (30 patients) by radiotherapy. All patients had follow-up for at least 1 year, 13 patients (37%) had follow-up for at least 5 years. Results: The 5-year local control rate was 78%. The 5-year local control rate for the few patients treated with radiotherapy alone was statistically similar to that for patients treated with surgery and radiotherapy (100% vs. 77%, p = 0.4). Multivariate analysis for factors affecting local control included sex, histology, age, treatment group, clinical T stage, initial histologic differentiation, and previously untreated vs. recurrent tumors, none of which was found to be significant. Conclusions: Both surgery plus radiotherapy and radiotherapy alone provide a relatively high rate of local control for patients with incidentally discovered perineural invasion secondary to skin cancer

  15. LCA as an environmental technology development performance indicator of engineered nano-materials and their application in polymers

    DEFF Research Database (Denmark)

    Miseljic, Mirko; Olsen, Stig Irving; Hauschild, Michael Zwicky

    Engineered nano‐material (ENM) application in products has in recent years developed to an important market segment but with rising environmental concerns, as the environmental life cycle impacts, especially toxicity of nanoparticles, are not assessed. Life cycle assessment (LCA) is a holistic tool...... project is aimed to be holistic and thereby include the entire life cycle of the nano‐polymer products and not be like the current frequently applied nano‐material LCA case study approaches where the life cycle is reduced and system boundaries substantially limited. In order to perform accurate...

  16. Occurrence of mesothelial/monocytic incidental cardiac excrescences in material from open-heart procedures: case reports and literature review.

    Science.gov (United States)

    Grossi, Vitor Gabriel Ribeiro; Lee, Karen; Demarchi, Léa Maria; Castelli, Jussara Bianchi; Aiello, Vera Demarchi

    2018-01-01

    Mesothelial/monocytic incidental cardiac excrescences (MICE) are unusual findings during the histological analysis of material from the pericardium, mediastinum, or other tissues collected in open-heart surgery. Despite their somewhat worrisome histological appearance, they show a benign clinical course, and further treatment is virtually never necessary. Hence, the importance of recognizing the entity relays in its differential diagnosis, as an unaware medical pathologist may misinterpret it for a malignant neoplasm. Other mesothelial and histiocytic proliferative lesions, sharing very close histological morphology and immunohistochemistry features with MICE, have been described in sites other than the heart or the mediastinum. This similarity has led to the proposal of the common denomination "histiocytosis with raisinoid nuclei." We report three cases from the pathology archives of the Heart Institute of São Paulo University (Incor/HC-FMUSP), diagnosed as "mesothelial/monocytic incidental cardiac excrescence," with immunohistochemical documentation, and provide a literature review of this entity.

  17. Clival Lesion incidentally discovered on cone-beam computed tomography: A case report and review of the literature

    Energy Technology Data Exchange (ETDEWEB)

    Jadhav, Aniket B.; Tadinada, Aditya; Rengasamy, Kandasamy; Lurie, Alan G. [Dept. of Oral and Maxillofacial Radiology, University of Connecticut School of Dental Medicine, Farmington (United States); Douglas, Fellows [Division of Diagnostic Sciences and Therapeutics, University of Connecticut School of Medicine, Farmington (United States)

    2014-06-15

    An osteolytic lesion with a small central area of mineralization and sclerotic borders was discovered incidentally in the clivus on the cone-beam computed tomography (CBCT) of a 27-year-old male patient. This benign appearance indicated a primary differential diagnosis of non-aggressive lesions such as fibro-osseous lesions and arrested pneumatization. Further, on magnetic resonance imaging (MRI), the lesion showed a homogenously low T1 signal intensity with mild internal enhancement after post-gadolinium and a heterogeneous T2 signal intensity. These signal characteristics might be attributed to the fibrous tissues, chondroid matrix, calcific material, or cystic component of the lesion; thus, chondroblastoma and chondromyxoid fibroma were added to the differential diagnosis. Although this report was limited by the lack of final diagnosis and the patient lost to follow-up, the incidental skull base finding would be important for interpreting the entire volume of CBCT by a qualified oral and maxillofacial radiologist.

  18. 76 FR 12070 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2011-03-04

    ... Energy's EROS operations in 2010: Marine mammals Biological impacts Company Structure Dates sighted... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and...

  19. 76 FR 35856 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2011-06-20

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations, notification is hereby...

  20. 75 FR 8921 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2010-02-26

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations, notification is hereby...

  1. 76 FR 33704 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2011-06-09

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations, notification is hereby...

  2. 77 FR 45341 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2012-07-31

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and...). SUMMARY: In accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations...

  3. 77 FR 10481 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2012-02-22

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations, notification is hereby...

  4. 77 FR 16539 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2012-03-21

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and...). SUMMARY: In accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations...

  5. 76 FR 23570 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2011-04-27

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations, notification is hereby...

  6. 75 FR 28566 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2010-05-21

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations, notification is hereby...

  7. 78 FR 22517 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2013-04-16

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and...). SUMMARY: In accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations...

  8. 75 FR 31423 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2010-06-03

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and...: In accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations, notification...

  9. 78 FR 13865 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2013-03-01

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and...). SUMMARY: In accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations...

  10. 75 FR 54851 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2010-09-09

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations, notification is hereby...

  11. 75 FR 38078 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2010-07-01

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations, notification is hereby...

  12. 77 FR 39485 - Incidental Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal...

    Science.gov (United States)

    2012-07-03

    ... Taking of Marine Mammals; Taking of Marine Mammals Incidental to the Explosive Removal of Offshore Structures in the Gulf of Mexico AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and...). SUMMARY: In accordance with the Marine Mammal Protection Act (MMPA) and implementing regulations...

  13. A limited LCA of bio-adipic acid: Manufacturing the nylon-6,6 precursor adipic acid using the benzoic acid degradation pathway from different feedstocks

    NARCIS (Netherlands)

    Duuren, van J.B.J.H.; Brehmer, B.; Mars, A.E.; Eggink, G.; Martins Dos Santos, V.A.P.; Sanders, J.P.M.

    2011-01-01

    A limited life cycle assessment (LCA) was performed on a combined biological and chemical process for the production of adipic acid, which was compared to the traditional petrochemical process. The LCA comprises the biological conversion of the aromatic feedstocks benzoic acid, impure aromatics,

  14. Leaving the lecture room and learning LCM: - Experiences from Aalborg University after 13 years and 1950 students on LCA and related issues

    DEFF Research Database (Denmark)

    Riisgaard, Henrik

    2003-01-01

    the above with focus on learning processes other than courses. The empirical data stems from 13 years experience of facilitating learning processes and a study of Aalborg University graduates with a professional career based on LCA. Besides ordinary LCA courses, this papers describes the problem...

  15. Study for a simplified LCA methodology adapted to bio-products. Final report

    International Nuclear Information System (INIS)

    2009-01-01

    Agricultural resources form a renewable stock of raw materials that can be used for various purposes: food supply, production of energy (including biofuels), bio-products and bio-based construction materials. The use of agricultural resources to produce bio-products is expanding in France and throughout the world, partly due to the presumed advantages of these products towards the environment. In this context, ADEME (the French Environment and Energy Management Agency) commissioned a study for the development of a methodological framework to evaluate the environmental impacts of bio-products. This study was also in charge of the identification of areas of improvement for the 'Bilan Produit', an environmental assessment tool developed by ADEME, in order to allow a future integration of bio-products. The first step of this study consisted of a comparative review of the existing bio-products' LCA (Life Cycle Assessment). This review underlined a deep heterogeneity among the methodologies used, as well as a lack of transparency in the results displayed. In a second step of the project, all the methodological issues in the evaluation of bio-products were studied, and recommendations for the resolution of each one of them have been proposed. These critical analyses are presented in individual fact-sheets, which detail the specific issues of each question, facts from the bibliographic review, the results of the tests conducted on three bio-products, and finally the methodological recommendations to answer the question. This project showed that some methodological recommendations had to be specified depending on the objective of the LCA: eco-design, environmental labeling or comparative LCA. The work conducted also identified some necessary improvements to the Bilan Produit tool, which come under four categories: addition of the missing inventories, integration of metadata regarding the inventories, consideration for the specific end-of-life scenarios of bio-products, and

  16. LCA of management strategies for RDF incineration and gasification bottom ash based on experimental leaching data.

    Science.gov (United States)

    Di Gianfilippo, Martina; Costa, Giulia; Pantini, Sara; Allegrini, Elisa; Lombardi, Francesco; Astrup, Thomas Fruergaard

    2016-01-01

    The main characteristics and environmental properties of the bottom ash (BA) generated from thermal treatment of waste may vary significantly depending on the type of waste and thermal technology employed. Thus, to ensure that the strategies selected for the management of these residues do not cause adverse environmental impacts, the specific properties of BA, in particular its leaching behavior, should be taken into account. This study focuses on the evaluation of potential environmental impacts associated with two different management options for BA from thermal treatment of Refuse Derived Fuel (RDF): landfilling and recycling as a filler for road sub bases. Two types of thermal treatment were considered: incineration and gasification. Potential environmental impacts were evaluated by life-cycle assessment (LCA) using the EASETECH model. Both non-toxicity related impact categories (i.e. global warming and mineral abiotic resource depletion) and toxic impact categories (i.e. human toxicity and ecotoxicity) were assessed. The system boundaries included BA transport from the incineration/gasification plants to the landfills and road construction sites, leaching of potentially toxic metals from the BA, the avoided extraction, crushing, transport and leaching of virgin raw materials for the road scenarios, and material and energy consumption for the construction of the landfills. To provide a quantitative assessment of the leaching properties of the two types of BA, experimental leaching data were used to estimate the potential release from each of the two types of residues. Specific attention was placed on the sensitivity of leaching properties and the determination of emissions by leaching, including: leaching data selection, material properties and assumptions related to emission modeling. The LCA results showed that for both types of BA, landfilling was associated with the highest environmental impacts in the non-toxicity related categories. For the toxicity

  17. Applying consequential LCA to support energy policy: Land use change effects of bioenergy production

    Energy Technology Data Exchange (ETDEWEB)

    Vázquez-Rowe, Ian, E-mail: ian.vazquez@tudor.lu; Marvuglia, Antonino; Rege, Sameer; Benetto, Enrico

    2014-02-01

    Luxembourg aims at complying with the EU objective of attaining a 14% use of bioenergy in the national grid by 2020. The increase of biomethane production from energy crops could be a valuable option in achieving this objective. However, the overall environmental benefit of such option is yet to be proven. Consequential Life Cycle Assessment (CLCA) has shown to be a useful tool to evaluate the environmental suitability of future energy scenarios and policies. The objective of this study was, therefore, to evaluate the environmental consequences of modifying the Luxembourgish agricultural system to increase maize production for biomethane generation. A total of 10 different scenarios were modelled using a partial equilibrium (PE) model to identify changes in land cultivation based on farmers' revenue maximisation, which were then compared to the baseline scenario, i.e. the state of the agricultural sector in 2009. The results were divided into three different consequential decision contexts, presenting differing patterns in terms of land use changes (LUCs) but with minor shifts in environmental impacts. Nevertheless, energy from maize production would imply substantially higher environmental impacts when compared with the current use of natural gas, mainly due to increases in climate change and agricultural land occupation impacts. The results are discussed based on the consequences they may generate on the bioenergy policy, the management of arable land, the changes in import–export flows in Luxembourg and LUCs in the domestic agricultural system. In addition, the specific PE + LCA method presented intends to be of use for other regional studies in which a high level of site-specific data is available. - Highlights: • Partial equilibrium (PE) model created for the agricultural sector in Luxembourg • PE model combined with a consequential LCA approach to support energy policy • The impact of LUCs due to the additional production of maize for energy was

  18. Applying consequential LCA to support energy policy: Land use change effects of bioenergy production

    International Nuclear Information System (INIS)

    Vázquez-Rowe, Ian; Marvuglia, Antonino; Rege, Sameer; Benetto, Enrico

    2014-01-01

    Luxembourg aims at complying with the EU objective of attaining a 14% use of bioenergy in the national grid by 2020. The increase of biomethane production from energy crops could be a valuable option in achieving this objective. However, the overall environmental benefit of such option is yet to be proven. Consequential Life Cycle Assessment (CLCA) has shown to be a useful tool to evaluate the environmental suitability of future energy scenarios and policies. The objective of this study was, therefore, to evaluate the environmental consequences of modifying the Luxembourgish agricultural system to increase maize production for biomethane generation. A total of 10 different scenarios were modelled using a partial equilibrium (PE) model to identify changes in land cultivation based on farmers' revenue maximisation, which were then compared to the baseline scenario, i.e. the state of the agricultural sector in 2009. The results were divided into three different consequential decision contexts, presenting differing patterns in terms of land use changes (LUCs) but with minor shifts in environmental impacts. Nevertheless, energy from maize production would imply substantially higher environmental impacts when compared with the current use of natural gas, mainly due to increases in climate change and agricultural land occupation impacts. The results are discussed based on the consequences they may generate on the bioenergy policy, the management of arable land, the changes in import–export flows in Luxembourg and LUCs in the domestic agricultural system. In addition, the specific PE + LCA method presented intends to be of use for other regional studies in which a high level of site-specific data is available. - Highlights: • Partial equilibrium (PE) model created for the agricultural sector in Luxembourg • PE model combined with a consequential LCA approach to support energy policy • The impact of LUCs due to the additional production of maize for energy was

  19. Comprehensive assessment of fruits and vegetables human health effects in a LCA context

    DEFF Research Database (Denmark)

    Stylianou, Katerina S.; Jolliet, O.; Fantke, Peter

    2016-01-01

    the environmental and nutritional effects of foods expressed in Disability Adjusted Life Years (DALYs). For the environmental health assessment we consider impact categories such as global warming and particulate matter (PM) as well as chemical exposure due to pesticide residues. Global warming and PM are assessed...... following a traditional LCA approach. For the pesticide residue exposure, we use publically available health impact scores derived from toxicological studies of numerous pesticide active ingredients. For the nutritional assessment we focus on the various health outcomes considered in the global burden...... in which the substituted food items are associated with negative health effects, such as red meat and trans-fat. Overall environmental health impacts associated with this addition are substantially smaller compared to nutritional benefits in each scenario, even when considering an uncertainty factor of 400...

  20. System expansion for handling co-products in LCA of sugar cane bio-energy systems

    DEFF Research Database (Denmark)

    Nguyen, T Lan T; Hermansen, John Erik

    2012-01-01

    This study aims to establish a procedure for handling co-products in life cycle assessment (LCA) of a typical sugar cane system. The procedure is essential for environmental assessment of ethanol from molasses, a co-product of sugar which has long been used mainly for feed. We compare system...... expansion and two allocation procedures for estimating greenhouse gas (GHG) emissions of molasses ethanol. As seen from our results, system expansion yields the highest estimate among the three. However, no matter which procedure is used, a significant reduction of emissions from the fuel stage...... in the abatement scenario, which assumes implementation of substituting bioenergy for fossil-based energy to reduce GHG emissions, combined with a negligible level of emissions from the use stage, keeps the estimate of ethanol life cycle GHG emissions below that of gasoline. Pointing out that indirect land use...

  1. Social LCA Scenarios: Engaging producers and consumers in new domestic oyster value chains in Denmark

    DEFF Research Database (Denmark)

    Wangel, Arne

    2014-01-01

    Efforts to develop a Social LCA methodology target the need to account for social impacts in the life cycle of existing products. Most often, the objective is to provide scientific support for decisions on alternative suppliers and terms of governance in the value chain of a particular product....... This paper suggests an application which shifts the focus to the design phase of life cycles of products and services yet to be constructed, not by a major lead company, but rather by start-ups and community groups. Health concerns and negative environmental impacts of industrial food production motivate...... the development and testing of new systems of growing, distribution and consumption. Ecological farmers contest conventional production methods, home delivery of fresh vegetables bypasses physical markets, and new food paradigms change meal preparation and dining experiences. One example is the entrepreneurs...

  2. Comparative techno-economic assessment and LCA of selected integrated sugarcane-based biorefineries.

    Science.gov (United States)

    Gnansounou, Edgard; Vaskan, Pavel; Pachón, Elia Ruiz

    2015-11-01

    This work addresses the economic and environmental performance of integrated biorefineries based on sugarcane juice and residues. Four multiproduct scenarios were considered; two from sugar mills and the others from ethanol distilleries. They are integrated biorefineries producing first (1G) and second (2G) generation ethanol, sugar, molasses (for animal feed) and electricity in the context of Brazil. The scenarios were analysed and compared using techno-economic value-based approach and LCA methodology. The results show that the best economic configuration is provided by a scenario with largest ethanol production while the best environmental performance is presented by a scenario with full integration sugar - 1G2G ethanol production. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Investor Outlook: Significance of the Positive LCA2 Gene Therapy Phase III Results.

    Science.gov (United States)

    Schimmer, Joshua; Breazzano, Steven

    2015-12-01

    Spark Therapeutics recently reported positive phase III results for SPK-RPE65 targeting the treatment of visual impairment caused by RPE65 gene mutations (often referred to as Leber congenital amaurosis type 2, or LCA2, but may include other retinal disorders), marking an important inflection point for the field of gene therapy. The results highlight the ability to successfully design and execute a randomized trial of a gene therapy and also reinforce the potentially predictive nature of early preclinical and clinical data. The results are expected to pave the way for the first approved gene therapy product in the United States and should sustain investor interest and confidence in gene therapy for many approaches, including retina targeting and beyond.

  4. A flexible matrix-based human exposure assessment framework suitable for LCA and CAA

    DEFF Research Database (Denmark)

    Jolliet, Olivier; Ernstoff, Alexi; Huang, Lei

    2016-01-01

    are not applicable to all types of near-field chemical releases from consumer products, e.g. direct dermal application. A consistent near-and far-field framework is needed for life cycle assessment (LCA) and chemical alternative assessment (CAA) to inform mitigation of human exposure to harmful chemicals. To close......Humans can be exposed to chemicals via near-field exposure pathways (e.g. through consumer product use) and far-field exposure pathways (e.g. through environmental emissions along product life cycles). Pathways are often complex where chemicals can transfer directly from products to humans during...... use or exchange between near-and far-field compartments until sub -fractions reach humans via inhalation, ingestion or dermal uptake. Currently, however, multimedia exposure models mainly focus on far-field exposure pathways. Metrics and modeling approaches used in far-field, emission-based models...

  5. Environmental assessment of Ammassuo Landfill (Finland) by means of LCA-modelling (EASEWASTE)

    DEFF Research Database (Denmark)

    Niskanen, A.; Manfredi, Simone; Christensen, Thomas Højlund

    2009-01-01

    The Old Ammassuo Landfill (Espoo, Finland) covers an area of 52 hectares and contains about 10 million tonnes of waste that was landfilled between 1987 and 2007. The majority of this waste was mixed, of which about 57% originated from households. This paper aims at describing the management...... of the Old Ammassuo Landfill throughout its operational lifetime (1987-2007), and at developing an environmental evaluation based on life-cycle assessment (LCA) using the EASEWASTE-model. The assessment criteria evaluate specific categories of impact, including standard impact categories, toxicity......) and ecotoxicity in water chronic (ETwc). The largest impact potential was found for SGR and amounted to 57.6 person equivalent (PE) per tonne of landfilled waste. However, the SGR impact may not be viewed as a significant issue in Finland as the drinking water is mostly supplied from surface water bodies. Overall...

  6. Choice of mineral fertilizer substitution principle strongly influences LCA environmental benefits of nutrient cycling in the agri-food system.

    Science.gov (United States)

    Hanserud, Ola Stedje; Cherubini, Francesco; Øgaard, Anne Falk; Müller, Daniel B; Brattebø, Helge

    2018-02-15

    Increased nutrient cycling in the agri-food system is a way to achieve a healthier nutrient stewardship and more sustainable food production. In life cycle assessment (LCA) studies, use of recycled fertilizer products is often credited by the substitution method, which subtracts the environmental burdens associated with avoided production of mineral fertilizer from the system under study. The environmental benefits from avoided fertilizer production can make an important contribution to the results, but different calculation principles and often implicit assumptions are used to estimate the amount of avoided mineral fertilizer. This may hinder comparisons between studies. The present study therefore examines how the choice of substitution principles influences LCA results. Three different substitution principles, called one-to-one, maintenance, and adjusted maintenance, are identified, and we test the importance of these in a case study on cattle slurry management. We show that the inventory of avoided mineral fertilizer varies greatly when the different principles are applied, with strong influences on two-thirds of LCA impact categories. With the one-to-one principle, there is a risk of systematically over-estimating the environmental benefits from nutrient cycling. In a sensitivity analysis we show that the difference between the principles is closely related to the application rate and levels of residual nutrients in the soil. We recommend that LCA practitioners first and foremost state and justify the substitution method they use, in order to increase transparency and comparability with other studies. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. A trade-based method for modelling supply markets in consequential LCA exemplified with Portland cement and bananas

    DEFF Research Database (Denmark)

    Sacchi, Romain

    2017-01-01

    This study proposes a method based on the analysis of trade networks over time for modelling the marginal supply of products in consequential life cycle assessment (LCA). It aims at increasing the geographical granularity of markets, accuracy of transport distances and modes and material losses d...

  8. Consensus building on the development of a stress-based indicator for LCA-based impact assessment of water consumption

    NARCIS (Netherlands)

    Boulay, Anne Marie; Bare, Jane; Camillis, De Camillo; Döll, Petra; Gassert, Francis; Gerten, Dieter; Humbert, Sebastien; Inaba, Atsushi; Itsubo, Norihiro; Lemoine, Yann; Margni, Manuele; Motoshita, Masaharu; Núñez, Montse; Pastor, A.V.; Ridoutt, Brad; Schencker, Urs; Shirakawa, Naoki; Vionnet, Samuel; Worbe, Sebastien; Yoshikawa, Sayaka; Pfister, Stephan

    2015-01-01

    Purpose: The WULCA group, active since 2007 on Water Use in LCA, commenced the development of consensus-based indicators in January 2014. This activity is planned to last 2 years and covers human health, ecosystem quality, and a stress-based indicator. This latter encompasses potential

  9. Use of LCA as a Tool for Building Ecodesign. A Case Study of a Low Energy Building in Spain

    Directory of Open Access Journals (Sweden)

    Alberto Jáñez

    2013-08-01

    Full Text Available This paper demonstrates how to achieve energy savings in the construction and operation of buildings by promoting the use of life cycle assessment techniques in the design for new buildings and for refurbishment. The paper aims to draw on the application of a specific methodology for low energy consumption, integrated planning, environmental performance evaluation of buildings, and design for sustainability and LCA techniques applied to buildings. The ENergy Saving through promotion of LIfe Cycle assessment in buildings (ENSLIC methodology based on LCA for use in an integral planning process has been promoted to stakeholders who require a means to optimize the environmental performance of buildings. Feedback from the stakeholders has facilitated the creation of simplified LCA guidelines, a systematic approach guiding the user through the alternative options regarding software choices, their strengths and weaknesses, the databases available, the usefulness of different indicators, aggregation, definition of limits and options for simplifying the process. As a result, this paper presents the applied results of a case study where this methodology is implemented serving as an energy savings evaluation tool for decision makers, end-users, professionals involved in the different stages of construction, etc. Finally, it is demonstrated how LCA can facilitate comparisons between different buildings, showing the influence of all variables on a building’s life cycle environmental impact and showing the potential for energy savings. Removing market barriers to sustainable construction is actually stricter and this is good news for promoting higher energy efficiency in buildings.

  10. Assessment of the GHG Reduction Potential from Energy Crops Using a Combined LCA and Biogeochemical Process Models: A Review

    Directory of Open Access Journals (Sweden)

    Dong Jiang

    2014-01-01

    Full Text Available The main purpose for developing biofuel is to reduce GHG (greenhouse gas emissions, but the comprehensive environmental impact of such fuels is not clear. Life cycle analysis (LCA, as a complete comprehensive analysis method, has been widely used in bioenergy assessment studies. Great efforts have been directed toward establishing an efficient method for comprehensively estimating the greenhouse gas (GHG emission reduction potential from the large-scale cultivation of energy plants by combining LCA with ecosystem/biogeochemical process models. LCA presents a general framework for evaluating the energy consumption and GHG emission from energy crop planting, yield acquisition, production, product use, and postprocessing. Meanwhile, ecosystem/biogeochemical process models are adopted to simulate the fluxes and storage of energy, water, carbon, and nitrogen in the soil-plant (energy crops soil continuum. Although clear progress has been made in recent years, some problems still exist in current studies and should be addressed. This paper reviews the state-of-the-art method for estimating GHG emission reduction through developing energy crops and introduces in detail a new approach for assessing GHG emission reduction by combining LCA with biogeochemical process models. The main achievements of this study along with the problems in current studies are described and discussed.

  11. An LCA-based evaluation of biomass to transportation fuels production and utilization pathways in a large port's context

    NARCIS (Netherlands)

    Tsalidis, George; El Discha, Fadhila; Korevaar, Gijsbert; Haije, Wim; de Jong, Wiebren; Kiel, Jaap

    This study evaluates whether a transition of large ports facilities to biofuel production for mobility improves the environmental performance and satisfies the renewable energy directive (RED) and it is the first LCA study that considers biofuel production from torrefied wood. The systems studied

  12. Thermodynamic resource indicators in LCA : A case study on the titania produced in Panzhihua city, southwest China

    NARCIS (Netherlands)

    Liao, Wenjie; Heijungs, Reinout; Huppes, Gjalt

    Purpose: While life cycle assessment (LCA) has standardized methods for assessing emission impacts, some comparable methods for the accounting or impact assessment of resource use exist, but are not as mature or standardized. This study contributes to the existing research by offering a

  13. Eco-efficient waste glass recycling: Integrated waste management and green product development through LCA

    International Nuclear Information System (INIS)

    Blengini, Gian Andrea; Busto, Mirko; Fantoni, Moris; Fino, Debora

    2012-01-01

    Highlights: ► A new eco-efficient recycling route for post-consumer waste glass was implemented. ► Integrated waste management and industrial production are crucial to green products. ► Most of the waste glass rejects are sent back to the glass industry. ► Recovered co-products give more environmental gains than does avoided landfill. ► Energy intensive recycling must be limited to waste that cannot be closed-loop recycled. - Abstract: As part of the EU Life + NOVEDI project, a new eco-efficient recycling route has been implemented to maximise resources and energy recovery from post-consumer waste glass, through integrated waste management and industrial production. Life cycle assessment (LCA) has been used to identify engineering solutions to sustainability during the development of green building products. The new process and the related LCA are framed within a meaningful case of industrial symbiosis, where multiple waste streams are utilised in a multi-output industrial process. The input is a mix of rejected waste glass from conventional container glass recycling and waste special glass such as monitor glass, bulbs and glass fibres. The green building product is a recycled foam glass (RFG) to be used in high efficiency thermally insulating and lightweight concrete. The environmental gains have been contrasted against induced impacts and improvements have been proposed. Recovered co-products, such as glass fragments/powders, plastics and metals, correspond to environmental gains that are higher than those related to landfill avoidance, whereas the latter is cancelled due to increased transportation distances. In accordance to an eco-efficiency principle, it has been highlighted that recourse to highly energy intensive recycling should be limited to waste that cannot be closed-loop recycled.

  14. Optimal utilization of waste-to-energy in an LCA perspective.

    Science.gov (United States)

    Fruergaard, T; Astrup, T

    2011-03-01

    Energy production from two types of municipal solid waste was evaluated using life cycle assessment (LCA): (1) mixed high calorific waste suitable for production of solid recovered fuels (SRF) and (2) source separated organic waste. For SRF, co-combustion was compared with mass burn incineration. For organic waste, anaerobic digestion (AD) was compared with mass burn incineration. In the case of mass burn incineration, incineration with and without energy recovery was modelled. Biogas produced from anaerobic digestion was evaluated for use both as transportation fuel and for heat and power production. All relevant consequences for energy and resource consumptions, emissions to air, water and soil, upstream processes and downstream processes were included in the LCA. Energy substitutions were considered with respect to two different energy systems: a present-day Danish system based on fossil fuels and a potential future system based on 100% renewable energy. It was found that mass burn incineration of SRF with energy recovery provided savings in all impact categories, but co-combustion was better with respect to Global Warming (GW). If all heat from incineration could be utilized, however, the two alternatives were comparable for SRF. For organic waste, mass burn incineration with energy recovery was preferable over anaerobic digestion in most impact categories. Waste composition and flue gas cleaning at co-combustion plants were critical for the environmental performance of SRF treatment, while the impacts related to utilization of the digestate were significant for the outcome of organic waste treatment. The conclusions were robust in a present-day as well as in a future energy system. This indicated that mass burn incineration with efficient energy recovery is a very environmentally competitive solution overall. Copyright © 2010 Elsevier Ltd. All rights reserved.

  15. A LCA (life cycle assessment) of the methanol production from sugarcane bagasse

    International Nuclear Information System (INIS)

    Reno, Maria Luiza Grillo; Lora, Electo Eduardo Silva; Palacio, Jose Carlos Escobar; Venturini, Osvaldo Jose; Buchgeister, Jens; Almazan, Oscar

    2011-01-01

    Nowadays one of the most important environmental issues is the exponential increase of the greenhouse effect by the polluting action of the industrial and transport sectors. The production of biofuels is considered a viable alternative for the pollution mitigation but also to promote rural development. The work presents an analysis of the environmental impacts of the methanol production from sugarcane bagasse, taking into consideration the balance of the energy life cycle and its net environmental impacts, both are included in a LCA (Life Cycle Assessment) approach. The evaluation is done as a case study of a 100,000 t/y methanol plant, using sugarcane bagasse as raw material. The methanol is produced through the BTL (Biomass to Liquid) route. The results of the environmental impacts were compared to others LCA studies of biofuel and it was showed that there are significant differences of environmental performance among the existing biofuel production system, even for the same feedstock. The differences are dependent on many factors such as farming practices, technology of the biomass conversion. With relation to the result of output/input ratio, the methanol production from sugarcane bagasse showed to be a feasible alternative for the substitution of an amount of fossil methanol obtained from natural gas. -- Highlights: → High and favorable energy ratio value of methanol from bagasse. → Sugarcane production has a low participation on environmental impacts. → The gasification and methanol synthesis can be combined in a biorefinery. → Farming biomass could cause the environmental impact land competition. → The trash of sugarcane can be used successfully in methanol production.

  16. Weight and see: Loading working memory improves incidental identification of irrelevant faces

    Directory of Open Access Journals (Sweden)

    David eCarmel

    2012-08-01

    Full Text Available Are task-irrelevant stimuli processed to a level enabling individual identification? This question is central both for perceptual processing models and for applied settings (e.g., eyewitness testimony. Lavie’s load theory proposes that working memory actively maintains attentional prioritization of relevant over irrelevant information. Loading working memory thus impairs attentional prioritization, leading to increased processing of task-irrelevant stimuli. Previous research has shown that increased working memory load leads to greater interference effects from response competing distractors. Here we test the novel prediction that increased processing of irrelevant stimuli under high working memory load should lead to a greater likelihood of incidental identification of entirely irrelevant stimuli. To test this, we asked participants to perform a word-categorization task while ignoring task-irrelevant images. The categorization task was performed during the retention interval of a working memory task with either low or high load (defined by memory set size. Following the final experimental trial, a surprise question assessed incidental identification of the irrelevant image. Loading working memory was found to improve identification of task-irrelevant faces, but not of building stimuli (shown in a separate experiment to be less distracting. These findings suggest that working memory plays a critical role in determining whether distracting stimuli will be subsequently identified.

  17. Can motivational signs prompt increases in incidental physical activity in an Australian health-care facility?

    Science.gov (United States)

    Marshall, A L; Bauman, A E; Patch, C; Wilson, J; Chen, J

    2002-12-01

    This study aimed to evaluate whether a stair-promoting signed intervention could increase the use of the stairs over the elevator in a health-care facility. A time-series design was conducted over 12 weeks. Data were collected before, during and after displaying a signed intervention during weeks 4-5 and 8-9. Evaluation included anonymous counts recorded by an objective unobtrusive motion-sensing device of people entering the elevator or the stairs. Self-report data on stair use by hospital staff were also collected. Stair use significantly increased after the first intervention phase (P = 0.02), but after the intervention was removed stair use decreased back towards baseline levels. Moreover, stair use did not significantly change after the re-introduction of the intervention. Lastly, stair use decreased below the initial baseline level during the final weeks of evaluation. Furthermore, there was no significant change in self-reported stair use by hospital staff. Therefore, the signed intervention aimed at promoting an increase in incidental physical activity produced small brief effects, which were not maintained. Further research is required to find more effective 'point of choice' interventions to increase incidental physical activity participation with more sustainable impact.

  18. The use of Meta-Regression Analysis to harmonize LCA literature: an application to GHG emissions of 2. and 3. generation biofuels

    International Nuclear Information System (INIS)

    Menten, Fabio; Cheze, Benoit; Patouillard, Laure; Bouvart, Frederique

    2013-01-01

    This article presents the results of a literature review performs with a meta-regression analysis (MRA) that focuses on the estimates of advanced biofuel Greenhouse Gas (GHG) emissions assessed with a Life Cycle Assessment (LCA) approach. The mean GHG emissions of both second (G2) and third generation (G3) biofuels and the effects of factors influencing these estimates are identified and quantified by means of specific statistical methods. 47 LCA studies are included in the database, providing 593 estimates. Each study estimate of the database is characterized by i) technical data/characteristics, ii) author's methodological choices and iii) typology of the study under consideration. The database is composed of both the vector of these estimates - expressed in grams of CO 2 equivalent per MJ of biofuel (g CO 2 eq/MJ) - and a matrix containing vectors of predictor variables which can be continuous or dummy variables. The former is the dependent variable while the latter corresponds to the explanatory variables of the meta-regression model. Parameters are estimated by mean of econometrics methods. Our results clearly highlight a hierarchy between G3 and G2 biofuels: life cycle GHG emissions of G3 biofuels are statistically higher than those of Ethanol which, in turn, are superior to those of BtL. Moreover, this article finds empirical support for many of the hypotheses formulated in narrative literature surveys concerning potential factors which may explain estimates variations. Finally, the MRA results are used to address the harmonization issue in the field of advanced biofuels GHG emissions thanks to the technique of benefits transfer using meta-regression models. The range of values hence obtained appears to be lower than the fossil fuel reference (about 83.8 in g CO 2 eq/ MJ). However, only Ethanol and BtL do comply with the GHG emission reduction thresholds for biofuels defined in both the American and European directives. (authors)

  19. Compensatory weight gain due to dopaminergic hypofunction: new evidence and own incidental observations

    Directory of Open Access Journals (Sweden)

    Bohr Iwo

    2008-12-01

    Full Text Available Abstract There is increasing evidence for a role of dopamine in the development of obesity. More specifically, dopaminergic hypofunction might lead to (overcompensatory food intake. Overeating and resulting weight gain may be induced by genetic predisposition for lower dopaminergic activity, but might also be a behavioral mechanism of compensating for decreased dopamine signaling after dopaminergic overstimulation, for example after smoking cessation or overconsumption of high palatable food. This hypothesis is in line with our incidental finding of increased weight gain after discontinuation of pharmaceutical dopaminergic overstimulation in rats. These findings support the crucial role of dopaminergic signaling for eating behaviors and offer an explanation for weight-gain after cessation of activities associated with high dopaminergic signaling. They further support the possibility that dopaminergic medication could be used to moderate food intake.

  20. Incidental focal FDG uptake in the parotid glands on PET/CT in patients with head and neck malignancy

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Young Lan; Yoon, Dae Young; Lim, Kyoung Ja; Yun, Eun Joo; Cho, Young Kwon [Hallym University College of Medicine, Department of Radiology, Kangdong Seong-Sim Hospital, Seoul (Korea, Republic of); Baek, Sora [Hallym University College of Medicine, Department of Nuclear Medicine, Kangdong Seong-Sim Hospital, Seoul (Korea, Republic of); Bae, Woo Jin; Chung, Eun Jae; Kwon, Kee Hwan [Hallym University College of Medicine, Department of Otorhinolaryngology, Ilsong Memorial Institute of Head and Neck Cancer, Kangdong Seong-Sim Hospital, Seoul (Korea, Republic of)

    2015-01-15

    To evaluate the prevalence and clinical significance of focal parotid lesions identified by {sup 18} F- FDG PET/CT in patients with nonparotid head and neck malignancies. From 3,638 PET/CT examinations using {sup 18} F-FDG conducted on 1,342 patients with nonparotid head and neck malignancies, we retrospectively identified patients showing incidental focal FDG uptake in the parotid glands. The diagnosis of parotid lesions was confirmed histopathologically or on imaging follow-up. Patient demographics, clinical features, maximum standardized uptake value (SUV{sub max}) on PET images, size and attenuation on corresponding contrast-enhanced CT images were assessed and correlated with the final diagnosis. The prevalence of incidental focal parotid FDG uptake on PET/CT was 2.1 % (95 % CI 1.4 - 3.0 %). Among 21 patients with focal parotid lesions confirmed histologically or on imaging follow-up, 7 (33.3 %) had malignant lesions (all metastases) and 14 (66.7 %) had benign lesions (four pleomorphic adenomas, two Warthin's tumours, one benign lymph node, one granulomatous lesion, six lesions without histopathological confirmation). There were no significant differences in age, sex, SUV{sub max} or CT findings between patients with benign and those with malignant lesions. Focal parotid FDG uptake on PET/CT in patients with head and neck malignancy warrants further investigations to ensure adequate therapy for incidental parotid lesions. (orig.)