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Sample records for immunohistochemistry twenty-seven archival

Diagnosis of lymphoma in paraffin wax sections by nested PCR and immunohistochemistry.

OpenAIRE

Kitamura, Y; Nanba, E; Inui, S; Tanigawa, T; Ichihara, K

1996-01-01

AIMS: To investigate whether nested polymerase chain reaction (PCR) and immunohistochemistry can be used to diagnose malignant lymphoma. METHODS: Paraffin wax embedded tissue sections from 31 patients with malignant lymphoma were analysed by nested PCR and immunohistochemistry using standard protocols. RESULTS: Nested PCR amplification of 1 pg DNA confirmed monoclonality in B cell lymphoma; PCR amplification of 10 pg DNA confirmed monoclonality in T cell lymphoma. Twenty seven (87%) samples w...
The Antigerminative Activity of Twenty-Seven Monoterpenes

Directory of Open Access Journals (Sweden)

Laura De Martino

2010-09-01

Full Text Available Monoterpenes, the main constituents of essential oils, are known for their many biological activities. The present work studied the potential biological activity of twenty-seven monoterpenes, including monoterpene hydrocarbons and oxygenated ones, against seed germination and subsequent primary radicle growth of Raphanus sativus L. (radish and Lepidium sativum L. (garden cress, under laboratory conditions. The compounds, belonging to different chemical classes, showed different potency in affecting both parameters evaluated. The assayed compounds demonstrated a good inhibitory activity in a dose-dependent way. In general, radish seed is more sensitive than garden cress and its germination appeares more inhibited by alcohols; at the highest concentration tested, the more active substances were geraniol, borneol, (±-β-citronellol and α-terpineol. Geraniol and carvone inhibited, in a significant way, the germination of garden cress, at the highest concentration tested. Radicle elongation of two test species was inhibited mainly by alcohols and ketones. Carvone inhibited the radicle elongation of both seeds, at almost all concentrations assayed, while 1,8-cineole inhibited their radicle elongation at the lowest concentrations (10−5 M, 10−6 M.
Dual pathology in Rasmussen's encephalitis: a study of seven cases and review of the literature.

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Takei, Hidehiro; Wilfong, Angus; Malphrus, Amy; Yoshor, Daniel; Hunter, Jill V; Armstrong, Dawna L; Bhattacharjee, Meenakshi B

2010-08-01

Dual pathology has previously been reported in less than 10% of cases of Rasmussen's encephalitis (RE). Given the rarity of RE, it appears unlikely that dual pathology in RE is merely a coincidence. We therefore reviewed all cases of RE experienced in our institution to assess for an additional/associated pathology. A total of seven patients with RE were identified in our archives. Seven children (4 boys and 3 girls, age range: 3-16 years, mean: 9.5 years) with medically refractory epilepsy underwent surgical resection for intractable seizures. The surgical specimens were examined with routine neurohistological techniques, and immunohistochemistry was performed with an extensive panel of antibodies for viruses, lymphocytes, microglia/macrophages, human leukocyte antigen (HLA)-DR, astrocytes, and neurons. Relevant literature was reviewed. Microscopically, all seven cases demonstrated the inflammatory pathology of RE in the cortex and white matter with leptomeningeal and perivascular lymphocytic infiltration, microglial nodules with/without neuronophagia, neuronal loss and gliosis. The HLA-DR antibody was extremely helpful in highlighting the extent of microglial cell proliferation/activation that was not appreciable with standard histology. An unexpected finding in all seven cases was the presence of cortical dysplasia. In our series of seven cases, there was co-occurrence of the inflammatory/destructive pathology of RE with malformative/dysplastic features in cortical architecture in 100% of cases, raising questions about the possible relationships between the two entities. Awareness of the possibility of dual pathology in RE is important for clinical and pathological diagnosis, and may affect the management and outcome of these patients. Immunohistochemistry is very helpful to make a definitive diagnosis of both pathologies.
Web Archives for the Analog Archivist: Using Webpages Archived by the Internet Archive to Improve Processing and Description

OpenAIRE

Gelfand, Aleksandr

2018-01-01

Twenty years ago the Internet Archive was founded with the wide-ranging mission of providing universal access to all knowledge. In the two decades since, that organization has captured and made accessible over 150 billion websites. By incorporating the use of Internet Archive's Wayback Machine into their workflows, archivists working primarily with analog records may enhance their ability in such tasks as the construction of a processing plan, the creation of more accurate historical descript...
Can Archival Tissue Reveal Answers to Modern Research Questions?: Computer-Aided Histological Assessment of Neuroblastoma Tumours Collected over 60 Years

Directory of Open Access Journals (Sweden)

Albert Chetcuti

2014-02-01

Full Text Available Despite neuroblastoma being the most common extracranial solid cancer in childhood, it is still a rare disease. Consequently, the unavailability of tissue for research limits the statistical power of studies. Pathology archives are possible sources of rare tissue, which, if proven to remain consistent over time, could prove useful to research of rare disease types. We applied immunohistochemistry to investigate whether long term storage caused any changes to antigens used diagnostically for neuroblastoma. We constructed and quantitatively assessed a tissue microarray containing neuroblastoma archival material dating between 1950 and 2007. A total of 119 neuroblastoma tissue cores were included spanning 6 decades. Fourteen antibodies were screened across the tissue microarray (TMA. These included seven positive neuroblastoma diagnosis markers (NB84, Chromogranin A, NSE, Ki-67, INI1, Neurofilament Protein, Synaptophysin, two anticipated to be negative (S100A, CD99, and five research antibodies (IL-7, IL-7R, JAK1, JAK3, STAT5. The staining of these antibodies was evaluated using Aperio ImageScope software along with novel pattern recognition and quantification algorithms. This analysis demonstrated that marker signal intensity did not decrease over time and that storage for 60 years had little effect on antigenicity. The construction and assessment of this neuroblastoma TMA has demonstrated the feasibility of using archival samples for research.
Pearls and pitfalls in neural CGRP immunohistochemistry

DEFF Research Database (Denmark)

Warfvinge, Karin; Edvinsson, Lars

2013-01-01

This review outlines the pearls and pitfalls of calcitonin-gene related protein (CGRP) immunohistochemistry of the brain. PEARLS: In 1985, CGRP was first described in cerebral arteries using immunohistochemistry. Since then, cerebral CGRP (and, using novel antibodies, its receptor components) has...
Assessment of Self-Archiving in Institutional Repositories: Across Disciplines

Science.gov (United States)

Xia, Jingfeng

2007-01-01

This research examined self-archiving practices by four disciplines in seven institutional repositories. By checking each individual item for its metadata and deposition status, the research found that a disciplinary culture is not obviously presented. Rather, self-archiving is regulated by a liaison system and a mandate policy.
Scientometric Analysis of Scientific Validity of Medical Archives Regarding Other Medical Journals in Bosnia and Herzegovina.

Science.gov (United States)

Masic, Izet; Begic, Edin; Zunic, Lejla

2016-02-01

Medical Archives is the oldest medical journal in Bosnia and Herzegovina (B&H) (founded in 1947.). A total of 104 articles were published in Medical Archives during 2015. Analyzing the type of articles, original articles are present in majority during 2015-80.7% (in last seven years, 561 (76%) were original out of 738). In last seven years, 651 (88.2%) articles were from the field of clinical medicine (preclinical disciplines, in the last three years are more represented than in previous years). Collaboration rate in 2015 was 0,92. Articles written in collaboration of five authors (21.1 %) are found to be predominant. From year to year, most often required time for a decision on acceptance or on the revision prior acceptance is between 50 and 60 days (30% of cases in 2015). During 2015, 47.1% of articles were originally from B&H (eleven countries were represented). H index of Medical Archive for 2014 was 12, and does not vary during the last decade. In 2015 in B&H about twenty-five journals are issued in the field of biomedical and life sciences in general (six are indexed on Medline/PubMed, one is indexed in the Science Citation Index Expanded (SCIE)/Web of Science base). According to GoogleScholar the biggest h5 index has Bosnian Journal of Basic Medical Sciences (BJBMS) and Medical Archives, while the biggest h5 median has BJBMS i Acta Informatica Medica. The highest H-index (13) in B&H has Izet Masic MD, PhD, Enver Zerem MD, PhD and Semir Vranic MD, PhD, while highest g-index (22) has Enver Zerem MD, PhD (analyzed by software package "Publish or Perish"). By comparing the state of medical publishing in B&H with neighboring countries (Croatia, Serbia, Montenegro), we have concluded that B&H is behind Croatia and Serbia by following parameters: Total Documents, Total Cites and H index but in front of Montenegro.
Chapter Twenty Seven

African Journals Online (AJOL)

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to arrest customers comprised unfair and discriminatory practices”. ... Even in French feminist theatre of 1870 -1914, Doestoevsky's fiction and Malaysian and ..... called “sex workers”) are compelled to pay tax to the government on their income. .... When a politician sells out his principles, or simply throws them to the wind to.
Measurement of Gene Expression in Archival Paraffin-Embedded Tissues

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Cronin, Maureen; Pho, Mylan; Dutta, Debjani; Stephans, James C.; Shak, Steven; Kiefer, Michael C.; Esteban, Jose M.; Baker, Joffre B.

2004-01-01

Throughout the last decade many laboratories have shown that mRNA levels in formalin-fixed and paraffin-embedded (FPE) tissue specimens can be quantified by reverse transcriptase-polymerase chain reaction (RT-PCR) techniques despite the extensive RNA fragmentation that occurs in tissues so preserved. We have developed RT-PCR methods that are sensitive, precise, and that have multianalyte capability for potential wide use in clinical research and diagnostic assays. Here it is shown that the extent of fragmentation of extracted FPE tissue RNA significantly increases with archive storage time. Probe and primer sets for RT-PCR assays based on amplicons that are both short and homogeneous in length enable effective reference gene-based data normalization for cross comparison of specimens that differ substantially in age. A 48-gene assay used to compare gene expression profiles from the same breast cancer tissue that had been either frozen or FPE showed very similar profiles after reference gene-based normalization. A 92-gene assay, using RNA extracted from three 10-μm FPE sections of archival breast cancer specimens (dating from 1985 to 2001) yielded analyzable data for these genes in all 62 tested specimens. The results were substantially concordant when estrogen receptor, progesterone receptor, and HER2 receptor status determined by RT-PCR was compared with immunohistochemistry assays for these receptors. Furthermore, the results highlight the advantages of RT-PCR over immunohistochemistry with respect to quantitation and dynamic range. These findings support the development of RT-PCR analysis of FPE tissue RNA as a platform for multianalyte clinical diagnostic tests. PMID:14695316
Parieto-occipital encephalomalacia in children; clinical and electrophysiological features of twenty-seven cases.

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Karaoğlu, Pakize; Polat, Ayşe İpek; Yiş, Uluç; Hız, Semra

2015-01-01

Brain injuries occurring at a particular time may cause damages in well-defined regions of brain. Perinatal hypoxic ischemic encephalopathy and hypoglycemia are some of the most common types of brain injuries. Neonatal hypoglycemia can cause abnormal myelination in parietal and occipital lobes resulting in parieto-occipital encephalomalacia. There is a small number of studies about clinical and electroencephalographic (EEG) features of children with parieto-occipital encephalomalacia. They might have important neurologic sequelae such as cortical visual loss, seizures, and psychomotor retardation. We aimed to evaluate the causes of parieto-occipital encephalomalacia and evaluate the clinical and electrophysiological features of children with parieto-occipital encephalomalacia. We evaluated clinical features and EEGs of 27 children with parieto-occipital encephalomalacia. Descriptive statistics were used. Hospitalization during the neonatal period was the most common cause (88.9%) of parieto-occipital brain injury. Eleven patients (40.7%) had a history of neonatal hypoglycemia. Twenty-three patients (85.2%) had epilepsy and nine of the epileptic patients (39%) had refractory seizures. Most of the patients had bilateral (50%) epileptic discharges originating from temporal, parietal, and occipital lobes (56.2%). However, some patients had frontal sharp waves and some had continuous spike and wave discharges during sleep. Visual abnormalities were evident in 15 (55.6%) patients. Twenty-two (81.5%) had psychomotor retardation. Fine motor skills, social contact and language development were impaired more than gross motor skills. In our study, most of the patients with parieto-occipital encephalomalacia had an eventful perinatal history. Epilepsy, psychomotor retardation, and visual problems were common neurologic complications.
Detection of apoptotic cells using immunohistochemistry

NARCIS (Netherlands)

Newbold, Andrea; Martin, Ben P.; Cullinane, Carleen; Bots, Michael

2014-01-01

Immunohistochemistry is commonly used to show the presence of apoptotic cells in situ. In this protocol, B-cell lymphoma cells are injected into recipient mice and, on tumor formation, the mice are treated with the apoptosis inducer vorinostat (a histone deacetylase inhibitor). Tumor samples are
Programmed Death-Ligand 1 Immunohistochemistry Testing

DEFF Research Database (Denmark)

Büttner, Reinhard; Gosney, John R; Skov, Birgit Guldhammer

2017-01-01

Purpose Three programmed death-1/programmed death-ligand 1 (PD-L1) inhibitors are currently approved for treatment of non-small-cell lung cancer (NSCLC). Treatment with pembrolizumab in NSCLC requires PD-L1 immunohistochemistry (IHC) testing. Nivolumab and atezolizumab are approved without PD-L1...
[Immunohistochemistry diagnosis of fungal infections].

Science.gov (United States)

Rocha, D C; Duarte, M I; Pagliari, C; de Oliveira, M S

1998-01-01

Because the mycosis incidence has increased a lot with the appearing of AIDS, the Immunohistochemistry study among fungus shows the importance of fast methods for their identification that have advantage of been a durable method in comparison with immunofluorescence and the possibility of making retrospective studies in material embedded in paraffin. The Immunohistochemistry reaction with Histoplasma capsulatum, Pneumocystis carinii; and Criptococcus neoformans antibodies were sensitive, specifics, and intensely positive in all the cases previously diagnosed as Histoplasmosis, Pneumocystosis and Cryptococcosis, without cross-reaction with other fungus; while the anti-Candida albicans antibody showed weak positiveness in four Histoplasmosis cases, in one of Paracoccidioidomycosis cases and Sporotrichosis case; and the reactions with the antibody anti-P. brasiliensis were intensely positive in all the Paracoccidioidomycosis cases and weakly positive in two Histoplasmosis and two of the four Candidiasis cases. The previous identification of each fungi on tissue sample was made by Grocott method. This preliminary study showed that it is necessary to use other kinds of antibody and fungus, in order to get more details about the possible occurrence of cross-reactions. We suggest the use of new antibodies, with new standardizations in order to find the best titles for each reaction and eliminate the cross-reactions.
MVP immunohistochemistry is a useful adjunct in distinguishing leiomyosarcoma from leiomyoma and leiomyoma with bizarre nuclei.

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Lintel, Nicholas J; Luebker, Stephen A; Lele, Subodh M; Koepsell, Scott A

2018-03-01

Morphologically, distinguishing between leiomyoma (LM) and leiomyosarcoma (LMS) is not always straightforward, especially with benign variants such as bizarre leiomyoma (BLM). To identify potential markers of malignancy in uterine smooth muscle tumors, proteomic studies were performed followed by assessment of protein expression by immunohistochemistry. Archival formalin-fixed, paraffin-embedded tissues from tumors (n = 23) diagnosed as LM, BLM, and LMS (using published criteria) were selected for the study. Sequential window acquisition of all theoretical fragment ion spectra mass spectrometry was applied to pooled samples of formalin-fixed, paraffin-embedded LM and LMS tumor tissue to assay the relative protein quantities and look for expression patterns differentiating the 2 tumor types. A total of 592 proteins were quantified, and 10 proteins were differentially expressed between LM and LMS. Select proteins were chosen for evaluation by immunohistochemistry (IHC) based on antibody availability and biologic relevance in the literature. IHC was performed on a tissue microarray, and intensity was evaluated using imaging software. Major vault protein (MVP) and catechol O-methyltransferase had 3.05 and 13.94 times higher expression in LMS relative to LM by sequential window acquisition of all theoretical fragment ion spectra mass spectrometry, respectively. By IHC, MVP (clone 1014; Santa Cruz Biotechnology, Dallas, TX) was found to be 50% sensitive and 100% specific when comparing LMS to LM. Catechol O-methyltransferase (clone FL-271; Santa Cruz Biotechnology) had a sensitivity of 38% and a specificity of 88%. Six of 7 BLM had expression of MVP similar to LM. Immunohistochemical staining for MVP is a useful adjunct in distinguishing LMS from LM and BLM in difficult cases. Copyright © 2018. Published by Elsevier Inc.
Standardization of positive controls in diagnostic immunohistochemistry

DEFF Research Database (Denmark)

Torlakovic, Emina E; Nielsen, Søren; Francis, Glenn

2015-01-01

Diagnostic immunohistochemistry (dIHC) has been practiced for several decades, with an ongoing expansion of applications for diagnostic use, and more recently for detection of prognostic and predictive biomarkers. However, standardization of practice has yet to be achieved, despite significant...
Archival Descriptions from the National Archives Catalog

Data.gov (United States)

National Archives and Records Administration — Archival Descriptions from the National Archives Catalog data set provides archival descriptions of the permanent holdings of the federal government in the custody...
Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization.

Science.gov (United States)

Pauletti, G; Godolphin, W; Press, M F; Slamon, D J

1996-07-04

Amplification and overexpression of the HER-2/neu gene occurs in 25-30% of human breast cancers. This genetic alteration is associated with a poor clinical prognosis in women with either node negative or node positive breast cancers. The initial studies testing this association were somewhat controversial and this controversy was due in large part to significant heterogeneity in both the methods and/or reagents used in testing archival material for the presence of the alteration. These methods included a number of solid matrix blotting techniques for DNA, RNA and protein as well as immunohistochemistry. Fluorescence in situ hybridization (FISH) represents the newest methodologic approach for testing for this genetic alteration. In this study, FISH is compared to Southern, Northern and Western blot analyses as well as immunohistochemistry in a large cohort of archival human breast cancer specimens. FISH was found to be superior to all other methodologies tested in assessing formalin fixed, paraffin embedded material for HER-2/neu amplification. The results from this study also confirm that overexpression of HER-2/neu rarely occurs in the absence of gene amplification in breast cancer (approximately 3% of cases). This method of analysis is rapid, reproducible and extremely reliable in detecting presence of HER-2/neu gene amplification and should have clinical utility.
Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine - Part 2: Immunohistochemistry Test Performance Characteristics

NARCIS (Netherlands)

Torlakovic, E.E.; Cheung, C.C.; D'Arrigo, C.; Dietel, M.; Francis, G.D.; Gilks, C.B.; Hall, J.A.; Hornick, J.L.; IBRAHIM, M.; Marchetti, A.; Miller, K.; Krieken, J.H.J.M. van; Nielsen, S.; Swanson, P.E.; Vyberg, M.; Zhou, X.; Taylor, C.R.

2017-01-01

All laboratory tests have test performance characteristics (TPCs), whether or not they are explicitly known to the laboratorian or the pathologist. TPCs are thus also an integral characteristic of immunohistochemistry (IHC) tests and other in situ, cell-based molecular assays such as DNA or RNA in
The mycobiota associated with paper archives and their potential control

Directory of Open Access Journals (Sweden)

SAIFELDIN A. F. EL-NAGERABI

2014-07-01

Full Text Available El-Nagerabi SAF, Elshafie AE, Al-Hinai UA. 2014. The mycobiota associated with paper archives and their potential control. Nusantara Bioscience 6: 19-25. Historical collections kept in archives and libraries represent a cultural and artistic heritage of innumerable value. Recently in Oman, more than seventy thousand documents were collected from different countries and displayed as archives showed evident sign of mold contamination. The objectives of the present study were to screen these archives for mold invasion and a test for the effective control measure. For this, 102 samples were collected from documents of different sources and incubated on potato dextrose agar (PDA at ambient temperature (25○C±2. The isolated fungi were identified microscopically and confirmed with DNA extraction, PCR and DNA sequencing. Twenty-two fungal species belonging to 11 genera were recovered. The genus Penicillium (46.8% was the most prevalent, followed by Aspergillus (30.7%, Cladosporium (7%, Rhizopus (4%, and Chaetomium (3.5% whereas the remaining 6 genera represent only 8%. Eleven species were previously reported from similar substrates, whereas 11 species and one genus are new records for the mycoflora of archives. Sodium hypochlorite at 0.3-5.2% completely inhibited the fungal growth of the 10 tested fungal isolates with minimum inhibition concentration at 0.7%. Fumigation of books with 0.7-5.2% sodium hypochlorite completely inhibited all fungi without evident damage of the documents or ink discoloration. Therefore, sodium hypochlorite can be recommended as effective and eco-friendly disinfectant for archives comparable to other hazardous chemicals.

Evaluation of Podoplanin Expression in Hepatocellular Carcinoma Using RNAscope and Immunohistochemistry - A Preliminary Report.

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Cioca, Andreea; Cimpean, Anca Maria; Ceausu, Raluca Amalia; Tarlui, Valeria; Toma, Alina; Marin, Irina; Raica, Marius

2017-01-01

Podoplanin (PDPN), a mucin-type transmembrane glycoprotein, is expressed in a variety of human cancer types, and contributes to tumor progression. Our goal was to evaluate PDPN expression in hepatocellular carcinoma (HCC) using both immunohistochemistry (IHC) and RNAscope in situ hybridization. Twenty patients with HCC who underwent partial hepatectomy with curative intent were retrospectively analyzed. IHC gave positive results in 11 cases, while RNAscope assay for PDPN detected amplification in 16 cases. A significant association was noted between PDPN protein expression and histological tumor grade (p=0.036). Four cases that had negative PDPN results by RNAscope were also negative by IHC, while the remaining five cases with negative results by IHC were positive by RNAscope. A positive relationship was found between PDPN mRNA protein expression (p<0.001). Our preliminary results suggest that PDPN contributes to the malignant potential of HCC. RNAscope proved to be a more sensitive and reliable method than IHC in PDPN detection. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
A twenty-seven kilometre film

CERN Multimedia

2009-01-01

For the past two weeks, Bram Conjaerts, a Belgian filmmaker, has been touring the CERN sites and surrounding countryside conducting research for his new documentary. The film will follow the entire 27 Km length of the LHC ring, but unlike most documentaries about the LHC, it will take place mostly above ground! Bram Conjaerts during his visit to CERN.While working towards his film degree in 2008, Bram Conjaerts won an award at the International Documentary Festival for his documentary "Henri and the Islands", an anthropological documentary about the smallest village in Belgium. In an unlikely change of subject matter he decided to use the prize money to make a film about the LHC. "With the money granted by the Flemish government, I wanted to create a documentary about something adventurous and something that I did not know about, " explains Conjaerts. "I started doing research about the LHC and CERN and I came across the fantasy of...
Web archives

DEFF Research Database (Denmark)

Finnemann, Niels Ole

2018-01-01

This article deals with general web archives and the principles for selection of materials to be preserved. It opens with a brief overview of reasons why general web archives are needed. Section two and three present major, long termed web archive initiatives and discuss the purposes and possible...... values of web archives and asks how to meet unknown future needs, demands and concerns. Section four analyses three main principles in contemporary web archiving strategies, topic centric, domain centric and time-centric archiving strategies and section five discuss how to combine these to provide...... a broad and rich archive. Section six is concerned with inherent limitations and why web archives are always flawed. The last sections deal with the question how web archives may fit into the rapidly expanding, but fragmented landscape of digital repositories taking care of various parts...
21 CFR 864.1860 - Immunohistochemistry reagents and kits.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Immunohistochemistry reagents and kits. 864.1860 Section 864.1860 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Biological Stains § 864.1860...
2015 Cataloging Hidden Special Collections and Archives Unconference and Symposium: Innovation, Collaboration, and Models. Proceedings of the CLIR Cataloging Hidden Special Collections and Archives Symposium (Philadelphia, Pennsylvania, March 12-13, 2015)

Science.gov (United States)

Oestreicher, Cheryl, Ed.

2015-01-01

The 2015 CLIR Unconference & Symposium was the capstone event to seven years of grant funding through CLIR's Cataloging Hidden Special Collections and Archives program. These proceedings group presentations by theme. Collaborations provides examples of multi-institutional projects, including one international collaboration; Student and Faculty…
Upfront immunohistochemistry improves specificity of Helicobacter pylori diagnosis. A French pathology laboratory point of view.

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Ginestet, Florent; Guibourg, Briac; Doucet, Laurent; Théreaux, Jérémie; Robaszkiewicz, Michel; Marcorelles, Pascale; Uguen, Arnaud

2017-10-01

There is no consensus about the histopathologic methods to detect Helicobacter pylori in gastric biopsies to date. We aimed to question about the value of upfront anti-H. pylori immunohistochemistry in this field. We led a retrospective study about the rate of H. pylori-positive gastric biopsies before and after the implementation of upfront immunohistochemistry, the inter-rater and intermethods agreements in H. pylori identification about Hematoxylin-Eosin Saffron (HES), Giemsa, and immunohistochemistry stains and the histopathologic features associated with low amounts of H. pylori. First, the rate of H. pylori-positive gastric biopsies significantly diminished after the implementation of upfront immunohistochemistry (from 21.15% to 12.56%, Ppylori infection before the use of immunohistochemistry. Secondly, immunohistochemistry was the most reproducible and performing stain (kappa values >0.80), but HES and Giemsa stains also presented good-to-very good agreements. Finally, less than 1% of gastric biopsies with inconspicuous H. pylori infection showed no mucosal injury pointing out that any HES-detected mucosal injury could help to preselect the gastric biopsies requiring ancillary stains for the detection of H. pylori. Albeit being considered as a gold standard in the detection of H. pylori, the interest of using immunohistochemistry as an upfront stain on gastric biopsies is still debated. In our opinion, its use in second line in case of ambiguous HE/HES-Giemsa result is more appropriate. Further effort is needed to optimize the inexpensive but feasible HE/HES-based detection of H. pylori. © 2017 John Wiley & Sons Ltd.
Diffusion-Weighted Magnetic Resonance Diagnosis of Local Recurrences of Prostate Cancer after Radical Prostatectomy: Preliminary Evaluation on Twenty-Seven Cases

Directory of Open Access Journals (Sweden)

Salvatore Francesco Carbone

2014-01-01

Full Text Available Objectives. To assess the diagnostic performance of diffusion-weighted MR imaging (DWI in patients affected by prostatic fossa (PF relapse after radical prostatectomy (RP for prostatic carcinoma (PC. Methods. Twenty-seven patients showing a nodular lesion in the PF at T2-weighted MR imaging after RP, with diagnosis of PC relapse established by biopsy or PSA determinations, were investigated by DWI. Two readers evaluated the DWI results in consensus and the apparent diffusion coefficient (ADC of the nodules, separately; a mean value was obtained (ADCm. Results. Relapses did not significantly differ in size in respect of postsurgical benign nodules. The DWI qualitative evaluation showed sensitivity, specificity, accuracy, ppv, and npv values, respectively, of 83.3%, 88.9%, 85.2%, 93.7%, and 72.7% (100%, 87.5%, 95.6%, 93.7%, and 100%, for nodules >6 mm. The intraclass correlation coefficient (ICC for ADC evaluation between the two readers was 0.852 (95% CI 0.661–0.935; P=0.0001. The ADCm values for relapses and benign nodules were, respectively, 0.98±0.21×10−3 mm2/sec and 1.24±0.32×10−3 mm2/sec (P=0.006. Sensitivity, specificity, accuracy, ppv and npv of ADCm were, respectively, 77.8%, 88.9%, 81.8%, 93.3%, and 66.7% (93.3%, 87.5%, 85.4%, 93.3%, and 87.5% for nodules >6 mm. Conclusions. Diffusion-weighted MR imaging is a promising tool in the management of a hyperintense nodule detected by T2-weighted sequences. This might have a relevant importance in contouring radiotherapy treatment volumes.
Carrier detection of duchenne and becker muscular dystrophy using muscle dystrophin immunohistochemistry

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Acary S. Bulle Oliveira

1992-12-01

Full Text Available To ascertain whether dystrophin immunohistochemistry could improve DMD/ BMD carrier detection, we analyzed 14 muscle biopsies from 13 DMD and one BMD probable and possible carriers. All women were also evaluated using conventional methods, including genetic analysis, clinical and neurological evaluation, serum CK levels, KMG, and muscle biopsy. In 6 cases, there was a mosaic of dystrophin-positive and dystrophin-deficient fibers that allowed to make the diagnosis of a carrier state. Comparing dystrophin immunohistochemistry to the traditional methods, it was noted that this method is less sensitive than serum CK measuremens, but is more sensitive than EMG and muscle biopsy. The use of dystrophin immunohistochemistry in addition to CK, EMG and muscle biopsy improved the accuracy of carrier detection. This method is also helpful to distinguish manifesting DMD carriers from patients with other neuromuscular diseases like limb-girdle muscular dystrophy and spinal muscular atrophy.
Immunohistochemistry and Polymerase Chain Reaction for Detection Human Papilloma Virus in Warts: A Comparative Study

Science.gov (United States)

Lee, Hong Sun; Lee, Ji Hyun; Choo, Ji Yoon; Byun, Hee Jin; Jun, Jin Hyun

2016-01-01

Background Immunohistochemistry and polymerase chain reaction (PCR) are the most widely used methods for the detection of viruses. PCR is known to be a more sensitive and specific method than the immunohistochemical method at this time, but PCR has the disadvantages of high cost and skilled work to use widely. With the progress of technology, the immunohistochemical methods used in these days has come to be highly sensitive and actively used in the diagnostic fields. Objective To evaluate and compare the usefulness of immunohistochemistry and PCR for detection human papilloma virus (HPV) in wart lesions. Methods Nine biopsy samples of verruca vulgaris and 10 of condyloma accuminatum were examined. Immunohistochemical staining using monoclonal antibody to HPV L1 capsid protein and PCR were done for the samples. DNA sequencing of the PCR products and HPV genotyping were also done. Results HPV detection rate was 78.9% (88.9% in verruca vulgaris, 70.0% in condyloma accuminatum) on immunohistochemistry and 100.0% for PCR. HPV-6 genotype showed a lower positivity rate on immunohistochemistry (50.0%) as compared to that of the other HPV genotypes. Conclusion Immunohistochemistry for HPV L1 capsid protein showed comparable sensitivity for detection HPV. Considering the high cost and great effort needed for the PCR methods, we can use immunohistochemistry for HPV L1 capsid protein with the advantage of lower cost and simple methods for HPV detection. PMID:27489431
Author! author!: creating a digital archive of publications in a hospital library setting.

Science.gov (United States)

Rourke, Diane; Samsundar, Devica Ramjit; Shalini, Channapatna

2005-01-01

Baptist Hospital of Miami has been honoring its staff authors annually during National Library Week since 1979, at the time the library was relocated. Upon "doing the math" and realizing that twenty-five years had passed, a special event was planned to celebrate the occasion in 2004. A merger of four hospitals in 1995 to form Baptist Health South Florida, and an addition of a fifth hospital in 2003 added into the complexity of these publications. Organizing the event led to the conclusion that there had to be a "better way" to manage the publication archive. This paper will include a look back at the event's past, present efforts to develop an archival database, and future plans to make articles available electronically to users, copyright permitting.
Attitudes of the Japanese public and doctors towards use of archived information and samples without informed consent: Preliminary findings based on focus group interviews

Directory of Open Access Journals (Sweden)

Fukuhara Shunichi

2002-01-01

Full Text Available Abstract Background The purpose of this study is to explore laypersons' attitudes toward the use of archived (existing materials such as medical records and biological samples and to compare them with the attitudes of physicians who are involved in medical research. Methods Three focus group interviews were conducted, in which seven Japanese male members of the general public, seven female members of the general public and seven physicians participated. Results It was revealed that the lay public expressed diverse attitudes towards the use of archived information and samples without informed consent. Protecting a subject's privacy, maintaining confidentiality, and communicating the outcomes of studies to research subjects were regarded as essential preconditions if researchers were to have access to archived information and samples used for research without the specific informed consent of the subjects who provided the material. Although participating physicians thought that some kind of prior permission from subjects was desirable, they pointed out the difficulties involved in obtaining individual informed consent in each case. Conclusions The present preliminary study indicates that the lay public and medical professionals may have different attitudes towards the use of archived information and samples without specific informed consent. This hypothesis, however, is derived from our focus groups interviews, and requires validation through research using a larger sample.
Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine. Part 3: Technical Validation of Immunohistochemistry (IHC) Assays in Clinical IHC Laboratories.

Science.gov (United States)

Torlakovic, Emina E; Cheung, Carol C; D'Arrigo, Corrado; Dietel, Manfred; Francis, Glenn D; Gilks, C Blake; Hall, Jacqueline A; Hornick, Jason L; Ibrahim, Merdol; Marchetti, Antonio; Miller, Keith; van Krieken, J Han; Nielsen, Soren; Swanson, Paul E; Vyberg, Mogens; Zhou, Xiaoge; Taylor, Clive R

2017-03-01

Validation of immunohistochemistry (IHC) assays is a subject that is of great importance to clinical practice as well as basic research and clinical trials. When applied to clinical practice and focused on patient safety, validation of IHC assays creates objective evidence that IHC assays used for patient care are "fit-for-purpose." Validation of IHC assays needs to be properly informed by and modeled to assess the purpose of the IHC assay, which will further determine what sphere of validation is required, as well as the scope, type, and tier of technical validation. These concepts will be defined in this review, part 3 of the 4-part series "Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine."
Main - RPSD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ... as rice. Data file File name: rpsd_main_sjis.zip File URL: ftp://ftp.biosciencedbc.jp/archive/rpsd/LATEST/r.../ftp.biosciencedbc.jp/archive/rpsd/LATEST/rpsd_main_utf8.zip File size: 120 KB Simple search URL http://togo...nse Update History of This Database Site Policy | Contact Us Main - RPSD | LSDB Archive ...
Protocol - RPD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...e version) File URL: ftp://ftp.biosciencedbc.jp/archive/rpd/LATEST/rpd_protocol_jp.zip File size: 535 KB Fil...e name: rpd_protocol_en.zip (English version) File URL: ftp://ftp.biosciencedbc.jp/archiv...tabase Database Description Download License Update History of This Database Site Policy | Contact Us Protocol - RPD | LSDB Archive ...
Archive & Data Management Activities for ISRO Science Archives

Science.gov (United States)

Thakkar, Navita; Moorthi, Manthira; Gopala Krishna, Barla; Prashar, Ajay; Srinivasan, T. P.

2012-07-01

ISRO has kept a step ahead by extending remote sensing missions to planetary and astronomical exploration. It has started with Chandrayaan-1 and successfully completed the moon imaging during its life time in the orbit. Now, in future ISRO is planning to launch Chandrayaan-2 (next moon mission), Mars Mission and Astronomical mission ASTROSAT. All these missions are characterized by the need to receive process, archive and disseminate the acquired science data to the user community for analysis and scientific use. All these science missions will last for a few months to a few years but the data received are required to be archived, interoperable and requires a seamless access to the user community for the future. ISRO has laid out definite plans to archive these data sets in specified standards and develop relevant access tools to be able to serve the user community. To achieve this goal, a Data Center is set up at Bangalore called Indian Space Science Data Center (ISSDC). This is the custodian of all the data sets of the current and future science missions of ISRO . Chandrayaan-1 is the first among the planetary missions launched/to be launched by ISRO and we had taken the challenge and developed a system for data archival and dissemination of the payload data received. For Chandrayaan-1 the data collected from all the instruments are processed and is archived in the archive layer in the Planetary Data System (PDS 3.0) standards, through the automated pipeline. But the dataset once stored is of no use unless it is made public, which requires a Web-based dissemination system that can be accessible to all the planetary scientists/data users working in this field. Towards this, a Web- based Browse and Dissemination system has been developed, wherein users can register and search for their area of Interest and view the data archived for TMC & HYSI with relevant Browse chips and Metadata of the data. Users can also order the data and get it on their desktop in the PDS
The Self-Organized Archive: SPASE, PDS and Archive Cooperatives

Science.gov (United States)

King, T. A.; Hughes, J. S.; Roberts, D. A.; Walker, R. J.; Joy, S. P.

2005-05-01

Information systems with high quality metadata enable uses and services which often go beyond the original purpose. There are two types of metadata: annotations which are items that comment on or describe the content of a resource and identification attributes which describe the external properties of the resource itself. For example, annotations may indicate which columns are present in a table of data, whereas an identification attribute would indicate source of the table, such as the observatory, instrument, organization, and data type. When the identification attributes are collected and used as the basis of a search engine, a user can constrain on an attribute, the archive can then self-organize around the constraint, presenting the user with a particular view of the archive. In an archive cooperative where each participating data system or archive may have its own metadata standards, providing a multi-system search engine requires that individual archive metadata be mapped to a broad based standard. To explore how cooperative archives can form a larger self-organized archive we will show how the Space Physics Archive Search and Extract (SPASE) data model will allow different systems to create a cooperative and will use Planetary Data System (PDS) plus existing space physics activities as a demonstration.
Variation in calculated human exposure. Comparison of calculations with seven European human exposure models

NARCIS (Netherlands)

Swartjes F; ECO

2003-01-01

Twenty scenarios, differing with respect to land use, soil type and contaminant, formed the basis for calculating human exposure from soil contaminants with the use of models contributed by seven European countries (one model per country). Here, the human exposures to children and children
Statistical Considerations for Immunohistochemistry Panel Development after Gene Expression Profiling of Human Cancers

Science.gov (United States)

Betensky, Rebecca A.; Nutt, Catherine L.; Batchelor, Tracy T.; Louis, David N.

2005-01-01

In recent years there have been a number of microarray expression studies in which different types of tumors were classified by identifying a panel of differentially expressed genes. Immunohistochemistry is a practical and robust method for extending gene expression data to common pathological specimens with the advantage of being applicable to paraffin-embedded tissues. However, the number of assays required for successful immunohistochemical classification remains unclear. We propose a simulation-based method for assessing sample size for an immunohistochemistry investigation after a promising gene expression study of human tumors. The goals of such an immunohistochemistry study would be to develop and validate a marker panel that yields improved prognostic classification of cancer patients. We demonstrate how the preliminary gene expression data, coupled with certain realistic assumptions, can be used to estimate the number of immunohistochemical assays required for development. These assumptions are more tenable than alternative assumptions that would be required for crude analytic sample size calculations and that may yield underpowered and inefficient studies. We applied our methods to the design of an immunohistochemistry study for glioma classification and estimated the number of assays required to ensure satisfactory technical and prognostic validation. Simulation approaches for computing power and sample size that are based on existing gene expression data provide a powerful tool for efficient design of follow-up genomic studies. PMID:15858152
Images - RPSD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ta file File name: rpsd_images.zip File URL: ftp://ftp.biosciencedbc.jp/archive/rpsd/LATEST/rpsd_images.zip ... History of This Database Site Policy | Contact Us Images - RPSD | LSDB Archive ...
Main - PLACE | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ilable. Data file File name: place_main.zip File URL: ftp://ftp.biosciencedbc.jp/archive/place/LATEST/place_...se Update History of This Database Site Policy | Contact Us Main - PLACE | LSDB Archive ...

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine

DEFF Research Database (Denmark)

Cheung, Carol C; D'Arrigo, Corrado; Dietel, Manfred

2017-01-01

The numbers of diagnostic, prognostic, and predictive immunohistochemistry (IHC) tests are increasing; the implementation and validation of new IHC tests, revalidation of existing tests, as well as the on-going need for daily quality assurance monitoring present significant challenges to clinical...... to develop and maintain high quality "fit-for-purpose" IHC testing in the era of precision medicine. This is the final part of the 4-part series "Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine."......The numbers of diagnostic, prognostic, and predictive immunohistochemistry (IHC) tests are increasing; the implementation and validation of new IHC tests, revalidation of existing tests, as well as the on-going need for daily quality assurance monitoring present significant challenges to clinical...... laboratories. There is a need for proper quality tools, specifically tissue tools that will enable laboratories to successfully carry out these processes. This paper clarifies, through the lens of laboratory tissue tools, how validation, verification, and revalidation of IHC tests can be performed in order...
Calorimeter Process Variable Archiving

International Nuclear Information System (INIS)

Huffman, David

2002-01-01

These steps were taken to maintain weekly archives: (1) Friday morning you stop the archiver and wait for it to finish writing data (the lock file will be removed from the directory); (2) move the current archive information to a PC via FTP; (3) remove all previous archive information in the previous directory; (4) move the current archive into the previous directory; (5) start a new archive; (6) burn a CDROM of the archive; and (7) copy the current archive to a specific directory. There are 2 ways to check if the Calorimeter Archiver is running, either through the WEB based front end or directly from a command line. Once the archiver is running it can be monitored from a WEB page. This only works with a browser launched from the online machine running the archiver. Each time the browser is reloaded there should be an update reported in the last write check field. You might have to wait a few minutes to see the update. Calorimetry currently takes readings every (300 sec.) 5 minutes. The second method to verify the archiver is running is to issue a command from a Linux cluster machine.
Analyzing Archival Intelligence: A Collaboration Between Library Instruction and Archives

Directory of Open Access Journals (Sweden)

Merinda Kaye Hensley

2014-07-01

Full Text Available Although recent archival scholarship promotes the use of primary sources for developing students’ analytical research skills, few studies focus on standards or protocols for teaching or assessing archival instruction. Librarians have designed and tested standards and learning assessment strategies for library instruction and archivists would do well to collaborate with and learn from their experience. This study examines lessons learned from one such collaboration between an instructional services librarian and archivist to evaluate and enhance archival instruction in the University Archives’ Student Life and Culture Archival Program (SLC Archives at the University of Illinois at Urbana-Champaign Library. Based on evaluative data from a student survey and in-depth interviews, the authors offer strategies for meeting and exceeding learning outcomes for archival intelligence more successfully.
Burkitt\\'s lymphoma in Uganda: the role of immunohistochemistry in ...

African Journals Online (AJOL)

Background: Haematoxylin and eosin staining has remained the standard diagnostic method for Burkitt\\'s lymphoma. Ancillary tests including immunohistochemistry, not widely available in developing countries, are important tools in verifying the diagnosis of lymphomas with equivocal morphological findings. Objective: To ...
Archives and the computer

CERN Document Server

Cook, Michael Garnet

1986-01-01

Archives and the Computer deals with the use of the computer and its systems and programs in archiving data and other related materials. The book covers topics such as the scope of automated systems in archives; systems for records management, archival description, and retrieval; and machine-readable archives. The selection also features examples of archives from different institutions such as the University of Liverpool, Berkshire County Record Office, and the National Maritime Museum.The text is recommended for archivists who would like to know more about the use of computers in archiving of
Archives and the computer

CERN Document Server

Cook, Michael Garnet

1980-01-01

Archives and the Computer deals with the use of the computer and its systems and programs in archiving data and other related materials. The book covers topics such as the scope of automated systems in archives; systems for records management, archival description, and retrieval; and machine-readable archives. The book also features examples of systems for records management from different institutions such as theTyne and Wear Archive Department, Dyfed Record Office, and the University of Liverpool. Included in the last part are appendices. Appendix A is a directory of archival systems, Appen
Main - KOME | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ntents List of datasets Data file File name: kome_main.zip File URL: ftp://ftp.biosciencedbc.jp/archive/kome...ase Database Description Download License Update History of This Database Site Policy | Contact Us Main - KOME | LSDB Archive ...
Reference - PLACE | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ailable. Data file File name: place_reference.zip File URL: ftp://ftp.biosciencedbc.jp/archive/place/LATEST/...ber About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Reference - PLACE | LSDB Archive ...
Discrimination of p53 immunohistochemistry-positive tumors by its staining pattern in gastric cancer

International Nuclear Information System (INIS)

Ando, Koji; Oki, Eiji; Saeki, Hiroshi; Yan, Zhao; Tsuda, Yasuo; Hidaka, Gen; Kasagi, Yuta; Otsu, Hajime; Kawano, Hiroyuki; Kitao, Hiroyuki; Morita, Masaru; Maehara, Yoshihiko

2015-01-01

Immunohistochemistry staining of p53 is a cheap and simple method to detect aberrant function of p53. However, there are some discrepancies between the result of immunohistochemistry staining and mutation analysis. This study attempted to find a new definition of p53 staining by its staining pattern. Immunohistochemistry staining of p53 and TP53 gene mutation analysis were performed in 148 gastric cancer patients. Also SNP-CGH array analysis was conducted to four cases. Positive staining of p53 was observed in 88 (59.5%) tumors. Tumors with positive p53 staining showed malignant features compared to negative tumors. Mutation of TP53 gene was observed in 29 (19.6%) tumors with higher age and differentiated type. In positive p53 tumors, two types could be distinguished; aberrant type and scattered type. With comparison to TP53 gene mutation analysis, all the scattered type had wild-type TP53 gene (P = 0.0003). SNP-CGH array showed that scattered-type tumors had no change in the structure of chromosome 17. P53-scattered-type staining tumors may reflect a functionally active nonmutated TP53 gene. In interpretation of p53 immunohistochemistry staining, distinguishing p53-positive tumors by their staining pattern may be important in gastric cancer
Alignment - SAHG | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...e URL: ftp://ftp.biosciencedbc.jp/archive/sahg/LATEST/sahg_alignment.zip File size: 12.0 MB Simple search UR...s Database Database Description Download License Update History of This Database Site Policy | Contact Us Alignment - SAHG | LSDB Archive ...
Exon - ASTRA | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ontents Exons in variants Data file File name: astra_exon.zip File URL: ftp://ftp.biosciencedbc.jp/archive/a... About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Exon - ASTRA | LSDB Archive ...
Access to Archives at the National Archives of Namibia ...

African Journals Online (AJOL)

This article is based on findings of a study of the National Archives of Namibia conducted in 2015. The study investigated the terms and conditions that guide access at the National Archives of Namibia. The study also investigated how the National Archives of Namibia has conformed to the ICA Code of Ethics and The ...
Locus - ASTRA | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...URL: ftp://ftp.biosciencedbc.jp/archive/astra/LATEST/astra_locus.zip File size: 887 KB Simple search URL htt...icing type (ex. cassette) About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Locus - ASTRA | LSDB Archive ...
Protein - TP Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...p_atlas_protein.zip File URL: ftp://ftp.biosciencedbc.jp/archive/tp_atlas/LATEST/...story of This Database Site Policy | Contact Us Protein - TP Atlas | LSDB Archive ...
IMMUNOHISTOCHEMISTRY VERSUS IMMUNOFLUORESENCE IN THE DIAGNOSIS OF AUTOIMMUNE BLISTERING DISEASES

Directory of Open Access Journals (Sweden)

Ana Maria Abreu Velez

2013-11-01

Full Text Available Introduction: In patients with autoimmune skin blistering diseases (ABDs, the diagnostic gold standard has classically been direct and indirect immunofluorescence (DIF and IIF, despite inherent technical problems of autofluorescence. Aim: We sought to overcome autofluorescence issues and compare the reliability of immunofluorescence versus immunohistochemistry (IHC staining in the diagnoses of these diseases. Methods: We tested via IHC for anti-human IgG, IgM, IgA, IgD, IgE, Kappa light chains, Lambda light chains, Complement/C3c, Complement/C1q, Complement/C3d, albumin and fibrinogen in 30 patients affected by a new variant of endemic pemphigus foliaceus in El Bagre, Colombia (El Bagre-EPF, and 30 control biopsies from the endemic area. We also tested archival biopsies from patients with ABDs whose diagnoses were made clinically, histopathologically and by DIF/IIF studies from 2 independent dermatopathology laboratories in the USA. Specifically, we tested 34 patients with bullous pemphigoid (BP, 18 with pemphigus vulgaris (PV, 8 with pemphigus foliaceus (PF, 14 with dermatitis herpetiformis (DH and 30 control skin samples from plastic esthetic surgery reduction surgeries. Results: The diagnostic correlation between IHC and DIF-IIF was almost 98% in most cases. IHC revealed evidence of autofluorescence around dermal blood vessels, dermal eccrine glands and neurovascular packages feeding skin appendices in ABDs; this autofluorescence may represent a non-specific immune response. Strong patterns of positivity were seen also in endothelial-mesenchymal cell junction-like structures, as well as between dermal fibrohistiocytic cells. In PV, we noted strong reactivity to neurovascular packages supplying sebaceous glands, as well as apocrine glands with edematous changes. Conclusions: We suggest that IHC is as reliable as DIF or IIF for the diagnosis of ABDs; our findings further suggest that what has previously been considered DIF/IIF autofluorescence
HyperArchiver: an EPICS archiver prototype based on Hypertable

International Nuclear Information System (INIS)

Giacchini, M.; Giovannini, L.; Montis, M.; Bassato, G.; Vasquez, J.A.; Prete, G.; Andrighetto, A.; Petkus, R.; Lange, R.; Kasemir, K.; Del Campo, M.; Jugo, J.

2012-01-01

This work started in the context of NSLS2 project at Brookhaven National Laboratory. The NSLS2 control system foresees a very high number of PV variables and has strict requirements in terms of archiving/retrieving rate: our goal was to store 10 K PV/sec and retrieve 4 K PV/sec for a group of 4 signals. The HyperArchiver is an EPICS Archiver implementation engined by Hypertable, an open source database whose internal architecture is derived from Google's Big Table. We discuss the performance of HyperArchiver and present the results of some comparative tests. (authors)
New Korean Record of Twenty Eight Species of the Family Ichneumonidae (Hymenoptera

Directory of Open Access Journals (Sweden)

Choi, Jin-Kyung

2014-04-01

Full Text Available We report twenty eight ichneumonid species new to Korea. These species belong to seven subfamilies. Among them five subfamilies, Diacritinae Townes, 1965, Microleptinae Townes, 1958, Orthocentrinae F$\\ddot{o} $ 수식 이미지rster, 1869, Orthopelmatinae Schmiedeknecht, 1910, Phrudinae Townes and Townes, 1949, are newly introduced to Korean fauna. All specimens are based on the insect collection of animal systematic laboratory at the Yeungnam University Gyeongsan Campus. Photographs of habitus of newly recorded subfamilies, diagnosis of 28 species and host information are provided.
Solubility - eSOL | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ta file File name: esol.zip File URL: ftp://ftp.biosciencedbc.jp/archive/esol/LAT... License Update History of This Database Site Policy | Contact Us Solubility - eSOL | LSDB Archive ...
Nike Twins Seven Seven: Nigerian Batik Artist.

Science.gov (United States)

LaDuke, Betty

1987-01-01

Chronicles the personal and professional life of Nike Twins Seven Seven (born 1951), a Nigerian batik artist, and her husband, Twins Seven Seven, a musician-artist, both of whom have received international acclaim. (BJV)
Tryptophan metabolism in breast cancers: molecular imaging and immunohistochemistry studies

International Nuclear Information System (INIS)

Juhász, Csaba; Nahleh, Zeina; Zitron, Ian; Chugani, Diane C.; Janabi, Majid Z.; Bandyopadhyay, Sudeshna; Ali-Fehmi, Rouba; Mangner, Thomas J.; Chakraborty, Pulak K.; Mittal, Sandeep; Muzik, Otto

2012-01-01

Introduction: Tryptophan oxidation via the kynurenine pathway is an important mechanism of tumoral immunoresistance. Increased tryptophan metabolism via the serotonin pathway has been linked to malignant progression in breast cancer. In this study, we combined quantitative positron emission tomography (PET) with tumor immunohistochemistry to analyze tryptophan transport and metabolism in breast cancer. Methods: Dynamic α-[ 11 C]methyl-L-tryptophan (AMT) PET was performed in nine women with stage II–IV breast cancer. PET tracer kinetic modeling was performed in all tumors. Expression of L-type amino acid transporter 1 (LAT1), indoleamine 2,3-dioxygenase (IDO; the initial and rate-limiting enzyme of the kynurenine pathway) and tryptophan hydroxylase 1 (TPH1; the initial enzyme of the serotonin pathway) was assessed by immunostaining of resected tumor specimens. Results: Tumor AMT uptake peaked at 5–20 min postinjection in seven tumors; the other two cases showed protracted tracer accumulation. Tumor standardized uptake values (SUVs) varied widely (2.6–9.8) and showed a strong positive correlation with volume of distribution values derived from kinetic analysis (P < .01). Invasive ductal carcinomas (n = 6) showed particularly high AMT SUVs (range, 4.7–9.8). Moderate to strong immunostaining for LAT1, IDO and TPH1 was detected in most tumor cells. Conclusions: Breast cancers show differential tryptophan kinetics on dynamic PET. SUVs measured 5–20 min postinjection reflect reasonably the tracer's volume of distribution. Further studies are warranted to determine if in vivo AMT accumulation in these tumors is related to tryptophan metabolism via the kynurenine and serotonin pathways.

Open archive solutions to traditional archive/library cooperation

Directory of Open Access Journals (Sweden)

Donatella Castelli

2003-09-01

Full Text Available The diffusion of Internet is changing the role of archives and libraries and it is opening a wide range of new possibilities. The new vision is that in few years it will be possible to cross-access multiple libraries, archives, museums, and data repositories. The implementation of this revolutionary vision requires the solution of a number of technical, organizational, sociological, and economical issues. Recently, the proposal of a new, low cost technical solution for open repositories of pre-print material, the Open Archives Initiative Protocol for Metadata Harvesting ( OAI-PMH, has greatly stimulated the discussion about these issues in many application frameworks. This paper overviews the status of this discussion in the library and conventional archives frameworks.
Main - TP Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...me: tp_atlas_en.zip File URL: ftp://ftp.biosciencedbc.jp/archive/tp_atlas/LATEST/...d License Update History of This Database Site Policy | Contact Us Main - TP Atlas | LSDB Archive ...
Biomarkers for ALK and ROS1 in Lung Cancer: Immunohistochemistry and Fluorescent In Situ Hybridization.

Science.gov (United States)

Luk, Peter P; Selinger, Christina I; Mahar, Annabelle; Cooper, Wendy A

2018-06-14

- A small proportion of non-small cell lung cancers harbor rearrangements of ALK or ROS1 genes, and these tumors are sensitive to targeted tyrosine kinase inhibitors. It is crucial for pathologists to accurately identify tumors with these genetic alterations to enable patients to access optimal treatments and avoid unnecessary side effects of less effective agents. Although a number of different techniques can be used to identify ALK- and ROS1-rearranged lung cancers, immunohistochemistry and fluorescence in situ hybridization are the mainstays. - To review the role of immunohistochemistry in assessment of ALK and ROS1 rearrangements in lung cancer, focusing on practical issues in comparison with other modalities such as fluorescence in situ hybridization. - This manuscript reviews the current literature on ALK and ROS1 detection using immunohistochemistry and fluorescence in situ hybridization as well as current recommendations. - Although fluorescence in situ hybridization remains the gold standard for detecting ALK and ROS1 rearrangement in non-small cell lung cancer, immunohistochemistry plays an important role and can be an effective screening method for detection of these genetic alterations, or a diagnostic test in the setting of ALK.
Main - AT Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ... name: at_atlas_en.zip File URL: ftp://ftp.biosciencedbc.jp/archive/at_atlas/LATE... Database Description Download License Update History of This Database Site Policy | Contact Us Main - AT Atlas | LSDB Archive ...
Flat Files - JSNP | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ... Data file File name: jsnp_flat_files File URL: ftp://ftp.biosciencedbc.jp/archiv...his Database Database Description Download License Update History of This Database Site Policy | Contact Us Flat Files - JSNP | LSDB Archive ...
OPS index - KOME | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...listed. Data file File name: kome_ops_index.zip File URL: ftp://ftp.biosciencedbc.jp/archive/kome/LATEST/kom...e History of This Database Site Policy | Contact Us OPS index - KOME | LSDB Archive ...
Clone - ClEST | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...le URL: ftp://ftp.biosciencedbc.jp/archive/clest/LATEST/clest_clone.zip File size: 660 KB Simple search URL ...ion Download License Update History of This Database Site Policy | Contact Us Clone - ClEST | LSDB Archive ...
Image files - RPD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ftp://ftp.biosciencedbc.jp/archive/rpd/LATEST/rpd_gel_image.zip File size: 38.5 MB Simple search URL - Data ... License Update History of This Database Site Policy | Contact Us Image files - RPD | LSDB Archive ...
Protein - AT Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ..._protein.zip File URL: ftp://ftp.biosciencedbc.jp/archive/at_atlas/LATEST/at_atla...About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Protein - AT Atlas | LSDB Archive ...
Cluster - ClEST | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...e File name: clest_cluster.zip File URL: ftp://ftp.biosciencedbc.jp/archive/clest/LATEST/clest_cluster.zip F...ownload License Update History of This Database Site Policy | Contact Us Cluster - ClEST | LSDB Archive ...
Gel table - RPD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...d_main.zip File URL: ftp://ftp.biosciencedbc.jp/archive/rpd/LATEST/rpd_main.zip File size: 1 KB Simple searc...iption Download License Update History of This Database Site Policy | Contact Us Gel table - RPD | LSDB Archive ...
tRNA - RMG | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...File URL: ftp://ftp.biosciencedbc.jp/archive/rmg/LATEST/rmg_trna.zip File size: 1 KB Simple search URL http:...ption Download License Update History of This Database Site Policy | Contact Us tRNA - RMG | LSDB Archive ...
Enhancers - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...d phase2.0 Data file File name: Enhancers File URL: ftp://ftp.biosciencedbc.jp/archive/fantom...load License Update History of This Database Site Policy | Contact Us Enhancers - FANTOM5 | LSDB Archive ...
All 5' EST - KOME | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...n of data contents 5' EST sequences Data file File name: CSV: kome_est_5end_all.zip File URL: ftp://ftp.biosciencedbc.jp/archiv...fasta.zip File URL: ftp://ftp.biosciencedbc.jp/archive/kome/LATEST/kome_est_5end_...se Description Download License Update History of This Database Site Policy | Contact Us All 5' EST - KOME | LSDB Archive ...
All 3' EST - KOME | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...n of data contents 3' EST sequences Data file File name: CSV: kome_est_3end_all.zip File URL: ftp://ftp.biosciencedbc.jp/archiv...fasta.zip File URL: ftp://ftp.biosciencedbc.jp/archive/kome/LATEST/kome_est_3end_...se Description Download License Update History of This Database Site Policy | Contact Us All 3' EST - KOME | LSDB Archive ...
About Libraries - AcEST | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ormat text file. Data file File name: acest_library.zip File URL: ftp://ftp.biosciencedbc.jp/archive/acest/L...ATEST/acest_library.zip File size: 2KB Simple search URL http://togodb.biosciencedbc.jp/togodb/view/archiv...s Database Database Description Download License Update History of This Database Site Policy | Contact Us About Libraries - AcEST | LSDB Archive ...
The Dora Lange Archive

DEFF Research Database (Denmark)

Holm, Isak Winkel; Bjering, Jens Christian Borrebye

2016-01-01

The first season of Nic Pizzolatto's True Detective (2014) is not only a show about a murder, but also a show about how to gather and organize information in an archive. Having identified two archival problems—its temporal and topical extension—the article turns to Jacques Derrida's Archive Fever......: a Freudian Impression in order to explain how the archiving problems of the crime investigation are, in fact, intrinsic to any archiving practice. Lastly, the article addresses the political significance of the show's archiving problems by help of Derrida's text on the American Constitution and of Hardt...
Measurement of gene expression in archival paraffin-embedded tissues: development and performance of a 92-gene reverse transcriptase-polymerase chain reaction assay.

Science.gov (United States)

Cronin, Maureen; Pho, Mylan; Dutta, Debjani; Stephans, James C; Shak, Steven; Kiefer, Michael C; Esteban, Jose M; Baker, Joffre B

2004-01-01

Throughout the last decade many laboratories have shown that mRNA levels in formalin-fixed and paraffin-embedded (FPE) tissue specimens can be quantified by reverse transcriptase-polymerase chain reaction (RT-PCR) techniques despite the extensive RNA fragmentation that occurs in tissues so preserved. We have developed RT-PCR methods that are sensitive, precise, and that have multianalyte capability for potential wide use in clinical research and diagnostic assays. Here it is shown that the extent of fragmentation of extracted FPE tissue RNA significantly increases with archive storage time. Probe and primer sets for RT-PCR assays based on amplicons that are both short and homogeneous in length enable effective reference gene-based data normalization for cross comparison of specimens that differ substantially in age. A 48-gene assay used to compare gene expression profiles from the same breast cancer tissue that had been either frozen or FPE showed very similar profiles after reference gene-based normalization. A 92-gene assay, using RNA extracted from three 10- micro m FPE sections of archival breast cancer specimens (dating from 1985 to 2001) yielded analyzable data for these genes in all 62 tested specimens. The results were substantially concordant when estrogen receptor, progesterone receptor, and HER2 receptor status determined by RT-PCR was compared with immunohistochemistry assays for these receptors. Furthermore, the results highlight the advantages of RT-PCR over immunohistochemistry with respect to quantitation and dynamic range. These findings support the development of RT-PCR analysis of FPE tissue RNA as a platform for multianalyte clinical diagnostic tests.
RT-PCR for detection of all seven genotypes of Lyssavirus genus.

Science.gov (United States)

Vázquez-Morón, S; Avellón, A; Echevarría, J E

2006-08-01

The Lyssavirus genus includes seven species or genotypes named 1-7. Rabies genotypes correlate with geographical distribution and specific hosts. Co-circulation of different lyssaviruses, imported cases, and the presence of unknown viruses, such as Aravan, Khujand, Irkut and West Caucasian Bat Virus, make it necessary to use generic methods able to detect all lyssaviruses. Primer sequences were chosen from conserved regions in all genotypes in order to optimise a generic RT-PCR. Serial dilutions of 12 RNA extracts from all seven Lyssavirus genotypes were examined to compare the sensitivity of the RT-PCR standardised in this study with a published RT-PCR optimised for EBLV1 detection and capable of amplifying RNA from all seven lyssaviruses. All seven genotypes were detected by both RT-PCRs, however, the sensitivity was higher with the new version of the test. Twenty samples submitted for rabies diagnosis were tested by the new RT-PCR. Eight out of 20 samples from six dogs, one horse and one bat were found positive, in agreement with immunofluorescence results. Seven samples from terrestrial mammals were genotype 1 and one from a bat was genotype 5. In conclusion, this method can be used to complement immunofluorescence for the diagnosis of rabies, enabling the detection of unexpected lyssaviruses during rabies surveillance.
Main data - RMG | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ftp://ftp.biosciencedbc.jp/archive/rmg/LATEST/rmg_main.zip File size: 1 KB Simple search URL http://togodb.b... This Database Database Description Download License Update History of This Database Site Policy | Contact Us Main data - RMG | LSDB Archive ...

PREIMS - AT Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...Targeted Proteins Research Program (TPRP). Data file File name: at_atlas_preims.zip File URL: ftp://ftp.biosciencedbc.jp/archiv...base Database Description Download License Update History of This Database Site Policy | Contact Us PREIMS - AT Atlas | LSDB Archive ...
EST data - RED | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...st.zip File URL: ftp://ftp.biosciencedbc.jp/archive/red/LATEST/red_est.zip File size: 629 KB Simple search U...ase Database Description Download License Update History of This Database Site Policy | Contact Us EST data - RED | LSDB Archive ...
ORF information - KOME | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ... File URL: ftp://ftp.biosciencedbc.jp/archive/kome/LATEST/kome_orf_infomation.zip File size: 526 KB Simple s...ut This Database Database Description Download License Update History of This Database Site Policy | Contact Us ORF information - KOME | LSDB Archive ...
An Empirical Comparison of Seven Iterative and Evolutionary Function Optimization Heuristics

Science.gov (United States)

Baluja, Shumeet

1995-01-01

This report is a repository of the results obtained from a large scale empirical comparison of seven iterative and evolution-based optimization heuristics. Twenty-seven static optimization problems, spanning six sets of problem classes which are commonly explored in genetic algorithm literature, are examined. The problem sets include job-shop scheduling, traveling salesman, knapsack, binpacking, neural network weight optimization, and standard numerical optimization. The search spaces in these problems range from 2368 to 22040. The results indicate that using genetic algorithms for the optimization of static functions does not yield a benefit, in terms of the final answer obtained, over simpler optimization heuristics. Descriptions of the algorithms tested and the encodings of the problems are described in detail for reproducibility.
Mapping data - KOME | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...tional Rice Genome Sequencing Project (IRGSP) Data file File name: kome_mapping_data.zip File URL: ftp://ftp.biosciencedbc.jp/archiv...(Transcriptional Unit) About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Mapping data - KOME | LSDB Archive ...
Spot table - RPD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...d_spot.zip File URL: ftp://ftp.biosciencedbc.jp/archive/rpd/LATEST/rpd_spot.zip F... cDNA. (multiple entries) About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Spot table - RPD | LSDB Archive ...
Public Heath in Colonial and Post-Colonial Ghana: Lesson-Drawing for The Twenty-First Century

Directory of Open Access Journals (Sweden)

Adu-Gyamfi, Samuel

2017-06-01

Full Text Available Public health in twenty-first century Ghana is mired with several issues ranging from the inadequacy of public health facilities, improper settlement planning, insanitary conditions, and the inadequacy of laws and their implementation. This situation compared to the colonial era is a direct contradiction. Development in the pre-colonial era to the colonial era sought to make the prevention of diseases a priority in the colonial administration. This was begun with the establishment of the health branch in 1909 as a response to the bubonic plague that was fast spreading in the colony. From here public health policies and strategies were enacted to help the diseases prevention cause. Various public health boards, the medical research institute or the laboratory branch, the waste management department, the use of preventive medicine and maintenance of good settlement planning and sanitation were public health measures in the colonial era. This research seeks to analyse the public health system in the colonial era so as to draw basic lessons for twenty-first century Ghana. Archival data and other secondary sources are reviewed and analysed to help draw these lessons. Richard Rose’s lesson-drawing approach was used to draw the lessons.
Archival standards, in archival open access software And offer appropriate software for internal archival centers

Directory of Open Access Journals (Sweden)

Abdolreza Izadi

2016-12-01

Full Text Available The purpose of this study is Study of Descriptive Metadata Standards in Archival open source software, to determine the most appropriate descriptive metadata standard (s and also Encoder Software support of these standards. The approach of present study is combination and library methods, Delphi and descriptive survey are used. Data gathering in library study is fiche, in the Delphi method is questionnaire and in descriptive survey is checklist. Statistical population contains 5 Archival open source software. The findings suggest that 5 metadata standards, consist of EAD, ISAD, EAC-CPF, ISAAR & ISDF, diagnosed appropriate by Delphi Panel members as the most appropriate descriptive metadata standards to use for archival software. Moreover, ICA-ATOM and Archivist toolkit in terms of support for standards that were suitable, diagnosed as the most appropriate archival software.
VLBA Archive &Distribution Architecture

Science.gov (United States)

Wells, D. C.

1994-01-01

Signals from the 10 antennas of NRAO's VLBA [Very Long Baseline Array] are processed by a Correlator. The complex fringe visibilities produced by the Correlator are archived on magnetic cartridges using a low-cost architecture which is capable of scaling and evolving. Archive files are copied to magnetic media to be distributed to users in FITS format, using the BINTABLE extension. Archive files are labelled using SQL INSERT statements, in order to bind the DBMS-based archive catalog to the archive media.
(reprocessed)CAGE peaks - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...g38/mm10). Data file File name: (reprocessed)CAGE_peaks (Homo sapiens) File URL: ftp://ftp.biosciencedbc.jp/archive/fantom...)CAGE_peaks (Mus musculus) File URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/d...his Database Site Policy | Contact Us (reprocessed)CAGE peaks - FANTOM5 | LSDB Archive ...
(reprocessed)pooled_ctss - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...e: (reprocessed)pooled_ctss (Homo sapiens) File URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/re...) File URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/reprocessed/mm10...ory of This Database Site Policy | Contact Us (reprocessed)pooled_ctss - FANTOM5 | LSDB Archive ...
License - PSCDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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Download - RPSD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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License - DMPD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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Disease - MicrobeDB.jp | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...File name: disease.tar.gz File URL: ftp://ftp.biosciencedbc.jp/archive/microbedb/...iption Download License Update History of This Database Site Policy | Contact Us Disease - MicrobeDB.jp | LSDB Archive ...
PSCID List - PSCDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...t.zip File URL: ftp://ftp.biosciencedbc.jp/archive/pscdb/LATEST/pscdb_pscid_list.zip File size: 24.4 KB Simp...nd-binding sites About This Database Database Description Download License Update History of This Database Site Policy | Contact Us PSCID List - PSCDB | LSDB Archive ...
Characterization of monoclonal antibodies against human thyrotropin and use in an immunoradiometric assay and immunohistochemistry

International Nuclear Information System (INIS)

Benkirane, M.; Bon, D.; Bellot, F.; Prince, P.; Delori, P.; Hassoun, J.; Carayon, P.

1987-01-01

Monoclonal antibodies were prepared against human thyrotropin. 13 different antibodies were characterized. Ten antibodies were of the IgG1 subclass. The affinities of the antibodies were in the range 10 9 -10 11 mol -1 .l. Four of them were specific for hTSH and did not react with hLH, hFSH, hCG or αhCG. Four reacted with these hormones and recognized the α subunit of hCG. One cross-reacted only with HFSH. The remaining four antibodies recognized the holo-hTSH only, and thus were designated as anti-conformational determinants. Monoclonal antibodies reacting with different antigenic determinants on the hTSH molecule defined seven clusters. Two of them were used to develop a simplified two-site sandwich radioimmunoassay in which one monoclonal antibody was immobilized on tubes (anti-βTSH) and another (anti-α) labelled with 125 I. This assay was highly specific and demonstrated a sensitivity level of 0.1 μIU/ml. Two monoclonal antibodies were used in immunohistochemistry and their quality and specificity was assessed in the detection of hTSH immunoreactivity in human pituitary biological sections. 20 refs.; 6 figs.; 2 tabs
Download - SSBD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ion Download License Update History of This Database Site Policy | Contact Us Download - SSBD | LSDB Archive ...
Archives: Mathematics Connection

African Journals Online (AJOL)

Items 1 - 9 of 9 ... Archives: Mathematics Connection. Journal Home > Archives: Mathematics Connection. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 9 of 9 Items. 2011 ...
Download - DGBY | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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Download - SAHG | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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Download - Metabolonote | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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License - GRIPDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...e Database Description Download License Update History of This Database Site Policy | Contact Us License - GRIPDB | LSDB Archive ...
License - GETDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...se Database Description Download License Update History of This Database Site Policy | Contact Us License - GETDB | LSDB Archive ...
Gaia Data Release 1. The archive visualisation service

Science.gov (United States)

Moitinho, A.; Krone-Martins, A.; Savietto, H.; Barros, M.; Barata, C.; Falcão, A. J.; Fernandes, T.; Alves, J.; Silva, A. F.; Gomes, M.; Bakker, J.; Brown, A. G. A.; González-Núñez, J.; Gracia-Abril, G.; Gutiérrez-Sánchez, R.; Hernández, J.; Jordan, S.; Luri, X.; Merin, B.; Mignard, F.; Mora, A.; Navarro, V.; O'Mullane, W.; Sagristà Sellés, T.; Salgado, J.; Segovia, J. C.; Utrilla, E.; Arenou, F.; de Bruijne, J. H. J.; Jansen, F.; McCaughrean, M.; O'Flaherty, K. S.; Taylor, M. B.; Vallenari, A.

2017-09-01

searches. Integration of the Aladin Lite and JS9 applications add support to the visualisation of HiPS and FITS maps. The production of the all-sky source density map that became the iconic image of Gaia DR1 is described in detail. Conclusions: On the day of DR1, over seven thousand users accessed the Gaia Archive visualisation portal. The system, running on a single machine, proved robust and did not fail while enabling thousands of users to visualise and explore the over one billion sources in DR1. There are still several limitations, most noticeably that users may only choose from a list of pre-computed visualisations. Thus, other visualisation applications that can complement the archive service are examined. Finally, development plans for Data Release 2 are presented.
Archives: Philosophical Papers

African Journals Online (AJOL)

Items 1 - 26 of 26 ... Archives: Philosophical Papers. Journal Home > Archives: Philosophical Papers. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 26 of 26 Items. 2008. Vol 37 ...
Archives: Kenya Veterinarian

African Journals Online (AJOL)

Items 1 - 21 of 21 ... Archives: Kenya Veterinarian. Journal Home > Archives: Kenya Veterinarian. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 21 of 21 Items. 2014. Vol 38, No ...
Archives: Agronomie Africaine

African Journals Online (AJOL)

Items 1 - 50 of 55 ... Archives: Agronomie Africaine. Journal Home > Archives: Agronomie Africaine. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 50 of 55 Items, 1 2 > >>. 2017 ...
A Critical Archival Pedagogy: The Lesbian Herstory Archives and a Course in Radical Lesbian Thought

Directory of Open Access Journals (Sweden)

Kailah R. Carden

2016-07-01

Full Text Available This paper is the story of a critical archival pedagogy that emerged through the undergraduate course Radical Lesbian Thought. As teachers and students, we dialogically co-constructed the praxis and content of the course throughout the semester. We employed archives throughout the course as theory, site, and pedagogy. In this paper we identify three archival frameworks: dialogue and difference, collaborative knowledge production, and archival methodology; and detail how they informed three course activities: reading and writing archival letters, visiting the Lesbian Herstory Archives, and completing final archival projects. We argue that archives provide theoretical and practical opportunities, in the tradition of critical pedagogy, to challenge and rearrange powered classroom structures and practices of thought.
License - JSNP | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - JSNP | LSDB Archive ...
Download - ASTRA | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...is Database Database Description Download License Update History of This Database Site Policy | Contact Us Download - ASTRA | LSDB Archive ...
Archives: Water SA

African Journals Online (AJOL)

Items 1 - 50 of 71 ... Archives: Water SA. Journal Home > Archives: Water SA. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 50 of 71 Items, 1 2 > >>. 2018. Vol 44, No 1 (2018) ...
License - KOME | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...out This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - KOME | LSDB Archive ...
Download - RED | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...t This Database Database Description Download License Update History of This Database Site Policy | Contact Us Download - RED | LSDB Archive ...
Download - GRIPDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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License - RMOS | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...out This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - RMOS | LSDB Archive ...
CAGE peaks - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...E Data file File name: CAGE_peaks File URL: ftp://ftp.biosciencedbc.jp/archive/fantom... This Database Database Description Download License Update History of This Database Site Policy | Contact Us CAGE peaks - FANTOM5 | LSDB Archive ...
License - ASTRA | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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License - SSBD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...thout notice. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - SSBD | LSDB Archive ...
Download - PSCDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...cess [here]. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Download - PSCDB | LSDB Archive ...

License - SAHG | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ut notice. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - SAHG | LSDB Archive ...
License - RPSD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...thout notice. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - RPSD | LSDB Archive ...
The Immunohistochemistry and Toluidine Blue Roles for Helicobacter pylori Detection in Patients with Gastritis

Science.gov (United States)

Tajalli, Raziye; Nobakht, Maliheh; Mohammadi-Barzelighi, Hajar; Agah, Shahram; Rastegar-Lari, Abdolaziz; Sadeghipour, Alireza

2013-01-01

Background: Helicobacter pylori, which is associated with many upper gastrointestinal diseases, is found in half of the population of the world. Several special stains and immunohistochemistry stain for H. pylori are available. The need for and usefulness of immunohistochemical (IHC) technique has been debated for years. Toluidine blue is a simple stain for microbiological studies and is easily available in laboratories. Therefore, this study was conducted to compare hematoxylin and eosin (H&E), Giemsa and toluidine blue staining with immunehistochemistry for detection of H. pylori in patients with gastritis and also to correlate the results of these staining methods with pathological grading. Methods: We reviewed 54 consecutive gastric biopsy specimens stained by H&E and Giemsa as well as by toluidine blue and immunohistochemistry stains for H. pylori. Results: H. pylori was positively identified by IHC in 43 (79.63%) patients, while positive samples were found in 18 (33.33%), 24 (44.44%) and 33 (61.11%) patients using H&E, Giemsa and toluidine blue staining methods. Our results showed that classical histological staining methods are not sensitive enough to identify low numbers or coccoid forms of organism, while toluidine blue and immunohistochemistry play an important role in detection of H. pylori infection. Conclusion: Toluidine blue has been proved to be much more reliable than H&E and Giemsa in detection of H. pylori. In addition, in post treatment biopsies and in biopsies with unexplained chronic active gastritis without histological evidence of H. pylori should have immunohistochemistry done to detect possible low density or coccoid form of organisms. PMID:23279833
Private political archives

Directory of Open Access Journals (Sweden)

Waldemar Chorążyczewski

2010-12-01

Full Text Available "Private political archives" are understood by me as all acts collected intently by a private person. These acts are connected with the person's participation in political life and gathered in order to be used in public activity as the source of argumentation and information about factors and mechanisms of political processes. Private political archives of the first half of the XVI century were mainly created by royal servants, often with reference to their job duties. These duties could inspire to collect political acts for private purposes. During the reign of Sigismund Augustus, archives of gentry activists were developed to small extent and they mainly focused on parliamentary life. Private political archives were created outside the executionist movement, namely in the community gathered around the royal court. After 1572, Crown and Lithuanian magnates greatly influenced the creation of political archives. Archives of lesser gentry, scarce and poor, did not disappear completely. However, they became difficult for identification. Therefore, developmental process concerned exclusively documentary "treasure troves" created by magnates. They had the financial means and possibilities to create truly valuable political archives. The same as in the previous period the dynamisms of executionist movement was reflected in political archival documentation, now the creation of patronage system and clientele, or traditionally understood magnate oligarchy, (depending on the point of view corresponded best to archives development. The heritage of previous generations was the treasure trove of patterns and solutions. However, this trove was used selectively, on one hand giving up patterns and rights that were uncomfortable, and, on the other, giving the value of precedence to unexpected acts that gained more importance or even new content in changed political conditions. The application of interpretation principle raised interest in old acts and patterns
BRC - MicrobeDB.jp | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...table). Data file File name: brc.tar.gz File URL: ftp://ftp.biosciencedbc.jp/archive/microbedb/LATEST/brc.ta...rains in JCM. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us BRC - MicrobeDB.jp | LSDB Archive ...
SRA - MicrobeDB.jp | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...e following table). Data file File name: sra.tar.gz File URL: ftp://ftp.biosciencedbc.jp/archive/microbedb/L...t This Database Database Description Download License Update History of This Database Site Policy | Contact Us SRA - MicrobeDB.jp | LSDB Archive ...
Gastrin-releasing peptide receptor imaging in human breast carcinoma versus immunohistochemistry

NARCIS (Netherlands)

de Wiele, Christophe Van; Phonteyne, Philippe; Pauwels, Patrick; Goethals, Ingeborg; Van den Broecke, Rudi; Cocquyt, Veronique; Dierckx, Rudi Andre

This study reports on the uptake of (99m)Tc-RP527 by human breast carcinoma and its relationship to gastrin-releasing peptide receptor (GRIP-R) expression as measured by immunohistochemistry (IHC). Methods: Nine patients referred because of a clinical diagnosis suggestive of breast carcinoma and 5
Archives: ORiON

African Journals Online (AJOL)

Items 1 - 27 of 27 ... Archives: ORiON. Journal Home > Archives: ORiON. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 27 of 27 Items. 2017. Vol 33, No 2 (2017) · Vol 33, No 1 ...
Download - RPD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data .... If it is, access [here]. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Download - RPD | LSDB Archive ...
License - RED | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ts might be changed without notice. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - RED | LSDB Archive ...
Download - JSNP | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data .... If it is, access [here]. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Download - JSNP | LSDB Archive ...
Movie collection - TogoTV | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...ols. Data file File name: movie File URL: ftp://ftp.biosciencedbc.jp/archive/togotv/movie/ File size: 200 GB...ata entries 1169 entries - About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Movie collection - TogoTV | LSDB Archive ...
License - GenLibi | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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License - ClEST | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

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The ERASMUS experiment archive

Science.gov (United States)

Isakeit, Dieter; Sabbatini, Massimo; Carey, William

2005-08-01

The Erasmus Experiment Archive is an electronic database, accessible through the Internet, that collects in a single reference repository scientific, technical and operational information regarding the experiments performed in the experiment facilities which fall under the responsibility of the ESA Directorate of Human Spaceflight, Microgravity and Exploration. The archive is operated, filled with content and kept up-to-date by the Erasmus User Centre. which forms part of the Directorate. The archive shares its records and is interoperable with similar experiment archives of the partner agencies NASA USA) and JAXA (Japan) through a mutually agreed standard for experiment records called the International Distributed Experiment Archive (IDEA).
Body weight - Open TG-GATEs | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...le URL: ftp://ftp.biosciencedbc.jp/archive/open-tggates/LATEST/open_tggates_body_...atabase Description Download License Update History of This Database Site Policy | Contact Us Body weight - Open TG-GATEs | LSDB Archive ...
(reprocessed)CAGE_peaks_annotation - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/reprocessed/hg38_latest/extra/CAGE_peaks_annotation/ ...e URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/reprocessed/mm10_latest/extra/CAGE_peaks_annotat...te History of This Database Site Policy | Contact Us (reprocessed)CAGE_peaks_annotation - FANTOM5 | LSDB Archive ...
(reprocessed)CAGE_peaks_expression - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...sciencedbc.jp/archive/fantom5/datafiles/reprocessed/hg38_latest/extra/CAGE_peaks_expression/ File size: 3.3 ...tp.biosciencedbc.jp/archive/fantom5/datafiles/reprocessed/mm10_latest/extra/CAGE_peaks_expression/ File size...f This Database Site Policy | Contact Us (reprocessed)CAGE_peaks_expression - FANTOM5 | LSDB Archive ...
Download - fRNAdb | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...Download License Update History of This Database Site Policy | Contact Us Download - fRNAdb | LSDB Archive ...
Download - TogoTV | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ... Download License Update History of This Database Site Policy | Contact Us Download - TogoTV | LSDB Archive ...

Paraffin-based immunohistochemistry in the evaluation of glomerular diseases in renal biopsies

International Nuclear Information System (INIS)

Rathore, M.U.; Khadim, M.T.; Atique, M.

2012-01-01

Objective: To determine sensitivity and specificity of paraffin-based immunohistochemistry in the evaluation of glomerular diseases in renal biopsies using immunofluorescence as gold standard. Study Design: Cross-sectional analytical study. Place and Duration of Study: Department of Histopathology, Armed Forces Institute of Pathology, Rawalpindi, from August 2008 to August 2009. Methodology: Seventy renal biopsy specimens fulfilling the inclusion criteria for light microscopy and immuno-fluorescence during the study period were evaluated. Antibodies to immunoglobulins (IgG, IgA, and IgM) and components of complement system (C3) were applied on 70 formalin-fixed paraffin-embedded renal biopsy specimens previously classified by means of light microscopy and immunofluorescence (IF). Staining for these antibodies was recorded as positive and negative for immunohistochemistry (IHC) and IF in paired proportions presuming IF as gold standard test. The sensitivity, specificity, positive predictive value and negative predictive value of individual antibody were calculated. Results: Of 70 patients, mean age was 33 +- 18 years ranging from 2 to 80 years. Forty five (64%) were males and 25 (36%) were females. The sensitivity, specificity and predictive values of individual antibodies to IgG, IgA, IgM and C3 were very low and generally in the range of 40 - 60%. Conclusion: The sensitivity, specificity and predictive values of immunohistochemistry on formalin-fixed paraffin-embedded renal biopsy specimens were very low and therefore, not suitable for evaluation of renal biopsies in current circumstances. (author)
The CORDEX archive in ESGF: a global archive for regional data

Science.gov (United States)

Juckes, Martin; Lautenschlager, Michael; Legutke, Stephanie; Bøssing Christensen, Ole; Kolax, Michael; Denvil, Sébastien

2013-04-01

The CORDEX program will produce regional model simulations for all areas of the globe, run by many modelling centres but with a consistent set of experimental parameters. Following the example set with the Coupled Model Inter-comparison Project, Phase 5 (CMIP5) archive of global climate simulations, a federated archive infrastructure will be exploited to support efficient distribution of the data and provide a single catalogue with a flexible search interface. Initial work towards establishing the European component of federated archive for CORDEX using the Earth System Grid Federation (ESGF) software has been started in the FP7 project IS-ENES (InfraStructure for the European Network for Earth System Modelling http://is.enes.org) and will be continued under IS-ENES2 (with additional support for an archive node at the University of Cape Town, S. Africa). The ESGF system allows data held at multiple sites to be accessed by users in a transparent manner. This poster will describe key adaptations of the ESGF CMIP5 infrastructure for CORDEX and some of the data services the system will provide. The vocabularies which underpin the facets of the search interface have been adapted and extended, a strategy for quality control has been developed. For the CMIP5 archive, most modelling centres contributing data also deployed an ESGF archive node. For the CORDEX archive a different approach will be followed because data is expected from a larger number of contributors without the resources needed to run such software. Instead, the CORDEX federated archive will be hosted at a moderate number of institutions with the required resources and expertise.
License - dbQSNP | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...escription Download License Update History of This Database Site Policy | Contact Us License - dbQSNP | LSDB Archive ...
License - eSOL | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...iption Download License Update History of This Database Site Policy | Contact Us License - eSOL | LSDB Archive ...
Archiving Websites

DEFF Research Database (Denmark)

Brügger, Niels

This book treats the micro archiving of websites, i.e. archiving by researchers, students or others without special technical knowledge who, using a standard computer, wish to save a website for further study. The phenomenon is discussed from the standpoint that Internet research must be able...
Erythrovirus B19 infection in acquired immunodeficiency syndrome: screening by histopathology, immunohistochemistry, and in situ hybridization

Directory of Open Access Journals (Sweden)

Sérgio Setúbal

2006-06-01

Full Text Available Erythrovirus B19 infects erythrocytic progenitors, transiently interrupting erythropoiesis. In AIDS patients it causes chronic anemia amenable to treatment. We looked for evidences of B19 infection in stored bone marrow material from patients with acquired immunodeficiency syndrome. Histological sections were made from stored paraffin blocks from 33 autopsies (39 blocks and 35 biopsies (45 blocks, 30 patients performed from 1988 to 2002. They were examined after hematoxylin-eosin (HE staining, immunohistochemical (IHC, and in situ hybridization. HE revealed intra-nuclear inclusion bodies ("lantern cells" suggesting B19 infection in 19 sections corresponding to 19 of 63 patients examined with this test. Seven of 78 sections subjected to immunohistochemistry were positive, corresponding to 7 of 58 patients examined with this test. Fourteen sections corresponding to 13 of the 20 HE and/or IHC positive patients were subjected to in situ hybridization, with six positives results. Among the 13 patients subjected to the three techniques, only one gave unequivocal positive results in all and was considered a true positive. The frequency of B19 infection (1/63 patients in the material examined can be deemed low.
Download - eSOL | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...Database Description Download License Update History of This Database Site Policy | Contact Us Download - eSOL | LSDB Archive ...
(Per)Forming Archival Research Methodologies

Science.gov (United States)

Gaillet, Lynee Lewis

2012-01-01

This article raises multiple issues associated with archival research methodologies and methods. Based on a survey of recent scholarship and interviews with experienced archival researchers, this overview of the current status of archival research both complicates traditional conceptions of archival investigation and encourages scholars to adopt…
CAGE_peaks_annotation - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...file File name: CAGE_peaks_annotation File URL: ftp://ftp.biosciencedbc.jp/archive/fantom...on Download License Update History of This Database Site Policy | Contact Us CAGE_peaks_annotation - FANTOM5 | LSDB Archive ...
pSort search result - KOME | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...name: kome_psort_search_result.zip File URL: ftp://ftp.biosciencedbc.jp/archive/kome/LATEST/kome_psort_searc...abase Description Download License Update History of This Database Site Policy | Contact Us pSort search result - KOME | LSDB Archive ...
Use of routine histopathology and factor VIII-related antigen/von Willebrand factor immunohistochemistry to differentiate primary hemangiosarcoma of bone from telangiectatic osteosarcoma in 54 dogs.

Science.gov (United States)

Giuffrida, M A; Bacon, N J; Kamstock, D A

2017-12-01

Hemangiosarcoma (HSA) of bone and telangiectatic osteosarcoma (tOSA) can appear similar histologically, but differ in histogenesis (malignant endothelial cells versus osteoblasts), and may warrant different treatments. Immunohistochemistry (IHC) for endothelial cell marker factor VIII-related antigen/von Willebrand factor (FVIII-RAg/vWF) is a well-documented ancillary test to confirm HSA diagnoses in soft tissues, but its use in osseous HSA is rarely described. Archived samples of 54 primary appendicular bone tumours previously diagnosed as HSA or tOSA were evaluated using combination routine histopathology (RHP) and IHC. Approximately 20% of tumours were reclassified on the basis of FVIII-RAg/vWF immunoreactivity, typically from an original diagnosis of tOSA to a reclassified diagnosis of HSA. No sample with tumour osteoid clearly identified on RHP was immunopositive for FVIII-RAg/vWF. RHP alone was specific but not sensitive for diagnosis of HSA, compared with combination RHP and IHC. Routine histopathological evaluation in combination with FVIII-RAg/vWF IHC can help differentiate canine primary appendicular HSA from tOSA. © 2016 John Wiley & Sons Ltd.
The prognostic and predictive value of sstr_2-immunohistochemistry and sstr_2-targeted imaging in neuroendocrine tumors

International Nuclear Information System (INIS)

Brunner, Philippe; Joerg, Ann-Catherine; Mueller-Brand, Jan; Glatz, Katharina; Bubendorf, Lukas; Radojewski, Piotr; Umlauft, Maria; Spanjol, Petar-Marko; Krause, Thomas; Dumont, Rebecca A.; Walter, Martin A.; Marincek, Nicolas; Maecke, Helmut R.; Briel, Matthias; Schmitt, Anja; Perren, Aurel

2017-01-01

Our aim was to assess the prognostic and predictive value of somatostatin receptor 2 (sstr_2) in neuroendocrine tumors (NETs). We established a tissue microarray and imaging database from NET patients that received sstr_2-targeted radiopeptide therapy with yttrium-90-DOTATOC, lutetium-177-DOTATOC or alternative treatment. We used univariate and multivariate analyses to identify prognostic and predictive markers for overall survival, including sstr_2-imaging and sstr_2-immunohistochemistry. We included a total of 279 patients. In these patients, sstr_2-immunohistochemistry was an independent prognostic marker for overall survival (HR: 0.82, 95 % CI: 0.67 - 0.99, n = 279, p = 0.037). In DOTATOC patients, sstr_2-expression on immunohistochemistry correlated with tumor uptake on sstr_2-imaging (n = 170, p < 0.001); however, sstr_2-imaging showed a higher prognostic accuracy (positive predictive value: +27 %, 95 % CI: 3 - 56 %, p = 0.025). Sstr_2-expression did not predict a benefit of DOTATOC over alternative treatment (p = 0.93). Our results suggest sstr_2 as an independent prognostic marker in NETs. Sstr_2-immunohistochemistry correlates with sstr_2-imaging; however, sstr_2-imaging is more accurate for determining the individual prognosis. (orig.)
Transnational archives: the Canadian case

Directory of Open Access Journals (Sweden)

Julia Creet

2011-05-01

Full Text Available This paper is a brief overview of the concept of the transnational archive as a counterpoint to the idea that a national archive is necessarily a locus of a static idea of nation. The Canadian national archives is used as a case study of an archives that was transnational in its inception, and one that has continued to change in its mandate and materials as a response to patterns in migration and changing notions of multiculturalism as a Canadian federal policy. It introduces the most recent formation of the transnational archive and its denizens: the genealogical archive inhabited by family historians.
Analysis list - ChIP-Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...://ftp.biosciencedbc.jp/archive/chip-atlas/LATEST/chip_atlas_analysis_list.zip File size: 44.8 KB Simple sea...e class. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Analysis list - ChIP-Atlas | LSDB Archive ...
Archives d’architectes et églises du XXe siècle

Directory of Open Access Journals (Sweden)

Simon Texier

2012-05-01

Full Text Available Depuis une vingtaine d’années, les archives d’architecture du XXe siècle, conservées au sein de la Cité de l’architecture et du patrimoine, ont été le support d’une considérable avancée de la recherche. L’architecture religieuse en a elle aussi bénéficié ; elle n’en souffre pas moins toujours d’un certain retard, et ce malgré l’extrême richesse des fonds d’architectes ou d’entrepreneurs. L’importance des études préparatoires et des projets non réalisés ou le développement massif de la construction d’édifices religieux après 1945 comptent parmi les axes des recherches possibles.Over the past twenty years, the 20th-century architectural archives held today at the Cité de l’Architecture et du Patrimoine have underpinned considerable progress in research in the history of architecture. Religious architecture has also benefited from this progress, although, despite the considerable interest of the archives of certain architects or building firms, studies in this particular field are still lacking,. Amongst the new research directions that can be suggested today, this article draws attention to two fields: the study of preliminary projects and of projects that, in the end, were not carried out, and the massive development of new religious building after 1945.
ArchiveDB—Scientific and technical data archive for Wendelstein 7-X

International Nuclear Information System (INIS)

Hennig, Christine; Maier, Josef; Grün, Martin; Krom, Jon; Blum, Torsten; Grahl, Michael; Heimann, Peter; Riemann, Heike; Laqua, Heike; Lewerentz, Marc; Spring, Anett; Werner, Andreas

2016-01-01

Highlights: • ArchiveDB archives all scientific and technical data of Wendelstein. • Primary index is the measured absolute time. • Continuously arising data is chunked in time for storage. • The Big Data Lambda Architecture pattern is applied. • The system is in place since a decade and a major change of underlying technology has been mastered. - Abstract: ArchiveDB is the data archive for all scientific and technical data collected at the Wendelstein 7-X project. It is a distributed system allowing continuous data archival. ArchiveDB has demanding requirements regarding performance efficiency (storage performance of 30 GB/s during experiments, expected storage amount of 1.4 PB/year), reliability (availability of 364 days/year), maintainability (testability) and portability (including change of hardware and software). Data acquisition with continuous operation and high time resolutions (up to nanoseconds scale) for physics data is supported as well as long-term recording up to 24 h/7 days for operational data (∼1 Hz rate). Moreover, all results of data analysis are stored in the archive. Another challenge, uniform retrieval of measured and analyzed data, allowing time and structure information as selection criteria, is mastered as well. The key concepts of data storage and retrieval are: (1) partitioning of incoming data in groups and stream, (2) chunking of data in boxes of manageable size covering a finite time period, and (3) indexing of data using absolute time as ordering and indexing criteria. Continuous operation of the ArchiveDB software and hardware for various systems and components relevant to Wendelstein 7-X has been done successfully for several years, thus, showing that the key requirements are satisfied. The overall data amount so far has reached 7 Terabyte over 9 years of data taking. Round-the-clock operation of the archive is in place since 5 years. Initial plasma operation OP1.1 of Wendelstein 7-X has been supported with no downtime
ArchiveDB—Scientific and technical data archive for Wendelstein 7-X

Energy Technology Data Exchange (ETDEWEB)

Hennig, Christine, E-mail: Christine.Hennig@ipp.mpg.de [Max Planck Institute for Plasma Physics, Wendelsteinstraße 1, 17491 Greifswald (Germany); Maier, Josef, E-mail: Josef.Maier@ipp.mpg.de [Max Planck Institute for Plasma Physics, Boltzmannstraße 2, 85748 Garching (Germany); Grün, Martin, E-mail: Martin.Gruen@ipp.mpg.de [FERCHAU Engineering GmbH, Steinmüllerallee 2, 51643 Gummersbach (Germany); Krom, Jon, E-mail: Jon.Krom@ipp.mpg.de [Max Planck Institute for Plasma Physics, Wendelsteinstraße 1, 17491 Greifswald (Germany); Blum, Torsten, E-mail: Torsten.Bluhm@ipp.mpg.de [Max Planck Institute for Plasma Physics, Wendelsteinstraße 1, 17491 Greifswald (Germany); Grahl, Michael, E-mail: Michael.Grahl@ipp.mpg.dem [Max Planck Institute for Plasma Physics, Wendelsteinstraße 1, 17491 Greifswald (Germany); Heimann, Peter, E-mail: Peter.Heimann@ipp.mpg.de [Max Planck Institute for Plasma Physics, Boltzmannstraße 2, 85748 Garching (Germany); Riemann, Heike, E-mail: Heike.Riemann@ipp.mpg.de [Max Planck Institute for Plasma Physics, Wendelsteinstraße 1, 17491 Greifswald (Germany); Laqua, Heike, E-mail: Heike.Laqua@ipp.mpg.de [Max Planck Institute for Plasma Physics, Wendelsteinstraße 1, 17491 Greifswald (Germany); Lewerentz, Marc, E-mail: Marc.Lewerentz@ipp.mpg.de [Max Planck Institute for Plasma Physics, Wendelsteinstraße 1, 17491 Greifswald (Germany); Spring, Anett, E-mail: Anett.Spring@ipp.mpg.de [Max Planck Institute for Plasma Physics, Wendelsteinstraße 1, 17491 Greifswald (Germany); Werner, Andreas, E-mail: Andreas.Werner@ipp.mpg.de [Max Planck Institute for Plasma Physics, Wendelsteinstraße 1, 17491 Greifswald (Germany)

2016-11-15

Highlights: • ArchiveDB archives all scientific and technical data of Wendelstein. • Primary index is the measured absolute time. • Continuously arising data is chunked in time for storage. • The Big Data Lambda Architecture pattern is applied. • The system is in place since a decade and a major change of underlying technology has been mastered. - Abstract: ArchiveDB is the data archive for all scientific and technical data collected at the Wendelstein 7-X project. It is a distributed system allowing continuous data archival. ArchiveDB has demanding requirements regarding performance efficiency (storage performance of 30 GB/s during experiments, expected storage amount of 1.4 PB/year), reliability (availability of 364 days/year), maintainability (testability) and portability (including change of hardware and software). Data acquisition with continuous operation and high time resolutions (up to nanoseconds scale) for physics data is supported as well as long-term recording up to 24 h/7 days for operational data (∼1 Hz rate). Moreover, all results of data analysis are stored in the archive. Another challenge, uniform retrieval of measured and analyzed data, allowing time and structure information as selection criteria, is mastered as well. The key concepts of data storage and retrieval are: (1) partitioning of incoming data in groups and stream, (2) chunking of data in boxes of manageable size covering a finite time period, and (3) indexing of data using absolute time as ordering and indexing criteria. Continuous operation of the ArchiveDB software and hardware for various systems and components relevant to Wendelstein 7-X has been done successfully for several years, thus, showing that the key requirements are satisfied. The overall data amount so far has reached 7 Terabyte over 9 years of data taking. Round-the-clock operation of the archive is in place since 5 years. Initial plasma operation OP1.1 of Wendelstein 7-X has been supported with no downtime
License - Q-TARO | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...thout notice. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - Q-TARO | LSDB Archive ...
Download - GenLibi | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...access [here]. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Download - GenLibi | LSDB Archive ...
Identification and characterization of twenty-seven short ...

Indian Academy of Sciences (India)

They have been successfully applied to resolve phylo- genetic relationships among various groups at different tax- onomic ranks (Nikaido et al. 2003; Chen et al. .... nizable flanking direct repeats (DRs) that are diagnostic of amplification via RNA intermediates during retrotransposi- tion (Weiner et al. 1986; Deininger 1989) ...

GPCR Interaction - GRIPDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us GRI...ed information (disease etc.). Data file File name: gripdb_main.zip File URL: ftp://ftp.biosciencedbc.jp/archive/gripdb/LATEST/gri...godb.biosciencedbc.jp/togodb/view/gripdb_main#en Data acquisition method PDB, Refseq Data analysis method - ...Number of data entries 409 entries Data item Description GRIP ID Interaction ID Main Title Interaction title...tabase Database Description Download License Update History of This Database Site Policy | Contact Us GPCR Interaction - GRIPDB | LSDB Archive ...
License - RGP gmap | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...nged without notice. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - RGP gmap | LSDB Archive ...
Download - Plabrain DB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us Plabrain...s Database Database Description Download License Update History of This Database Site Policy | Contact Us Download - Plabrain DB | LSDB Archive ...
National Archives Catalog and API

Data.gov (United States)

National Archives and Records Administration — The National Archives Catalog is the online catalog of NARA's nationwide holdings in the Washington, DC area, Regional Archives, and Presidential Libraries.
Lessons learned from planetary science archiving

Science.gov (United States)

Zender, J.; Grayzeck, E.

2006-01-01

The need for scientific archiving of past, current, and future planetary scientific missions, laboratory data, and modeling efforts is indisputable. To quote from a message by G. Santayama carved over the entrance of the US Archive in Washington DC “Those who can not remember the past are doomed to repeat it.” The design, implementation, maintenance, and validation of planetary science archives are however disputed by the involved parties. The inclusion of the archives into the scientific heritage is problematic. For example, there is the imbalance between space agency requirements and institutional and national interests. The disparity of long-term archive requirements and immediate data analysis requests are significant. The discrepancy between the space missions archive budget and the effort required to design and build the data archive is large. An imbalance exists between new instrument development and existing, well-proven archive standards. The authors present their view on the problems and risk areas in the archiving concepts based on their experience acquired within NASA’s Planetary Data System (PDS) and ESA’s Planetary Science Archive (PSA). Individual risks and potential problem areas are discussed based on a model derived from a system analysis done upfront. The major risk for a planetary mission science archive is seen in the combination of minimal involvement by Mission Scientists and inadequate funding. The authors outline how the risks can be reduced. The paper ends with the authors view on future planetary archive implementations including the archive interoperability aspect.
Resources for the User's Guide to the Royal Hetman's Archives in archives and library collections

Directory of Open Access Journals (Sweden)

Krzysztof Syta

2012-12-01

Full Text Available This article is an overview of archival collections with provenance of hetman's archives, but physically separated into collections in archives and libraries across Poland (Kraków, Kórnik, Łódź, Poznań, Warszawa and also Ukraine (Kiev, Lviv. Research, which later became an inspiration for this overview, has been conducted mainly in the early 90s. In the light of the above, this article does not claim to be called a "guide" to the royalhetmans' archives of the sixteenth through to the eighteenth century, but it could be viewed as an outline of such archival finding aid. This overview focuses on characteristics of different types of archival material, which author considered integrally connected to holding of an office of hetman, i.e.: personal, administrative and military, judiciary, financial, and also correspondence. Qualification criteria may raise some concerns, because selection of archives is subjective by nature, but also because in the discussed time period there was social consensus on the fact that one's private life and public sphere would overlap. Most of the archival materials used in this study comes from the hetman's archives of the eighteenth century (Jan Clement Branicki's; Franciszek Ksawery Branicki's; Stanisław Mateusz, Wacław, Seweryn Rzewuski's and Adam Mikołaj Sieniawski's. Eighteen century is considered to be the peak of development of private archives, which - without a doubt - had great impact on the preservation of hetman's archives of that period. Moreover, the fact that there is significantly larger collection of hetman's archives of that period, compared to previous two centuries, is the result of the hetman's office having a special place within the political system of the Polish-Lithuanian Commonwealth.
License - fRNAdb | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...be changed without notice. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - fRNAdb | LSDB Archive ...
License - AT Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ... might be changed without notice. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - AT Atlas | LSDB Archive ...
License - TP Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ... might be changed without notice. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - TP Atlas | LSDB Archive ...
Archives: Ethiopian Veterinary Journal

African Journals Online (AJOL)

Items 1 - 16 of 16 ... Archives: Ethiopian Veterinary Journal. Journal Home > Archives: Ethiopian Veterinary Journal. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 16 of 16 Items ...
Archives: Nigerian Veterinary Journal

African Journals Online (AJOL)

Items 1 - 49 of 49 ... Archives: Nigerian Veterinary Journal. Journal Home > Archives: Nigerian Veterinary Journal. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 49 of 49 Items ...
Archives: Continuing Medical Education

African Journals Online (AJOL)

Items 51 - 88 of 88 ... Archives: Continuing Medical Education. Journal Home > Archives: Continuing Medical Education. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 51 - 88 of 88 ...
Archives: African Studies Monographs

African Journals Online (AJOL)

Archives: African Studies Monographs. Journal Home > Archives: African Studies Monographs. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 5 of 5 Items. 2007. Vol 8 (2007) ...
Theoretical currents of Archival Science

Directory of Open Access Journals (Sweden)

Carlos Alberto Ávila Araújo

2013-08-01

Full Text Available Archival Science was formed, as a scientific discipline, in the late nineteenth century, from the consolidation of a custody and heritage model. In the twentieth century, several theories have been developed, systematized in this article in four axes. As a result, Archival Science has expanded its scope of studies. As a result of this expansion, there are contemporary perspectives with systemic models, covering different types of archives, concerned with the sociocultural context of the archives, and also insering digital technologies in the practice of archives.
GPCR Mutation information - GRIPDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us GRI...s and exposed in molecular surface. Data file File name: gripdb_mutation_info.zip File URL: ftp://ftp.biosciencedbc.jp/archive/gri...pdb/LATEST/gripdb_mutation_info.zip File size: 766 bytes Si...mple search URL http://togodb.biosciencedbc.jp/togodb/view/gripdb_mutation_info#en Data acquisition method P... Site Policy | Contact Us GPCR Mutation information - GRIPDB | LSDB Archive ...
Archives: Malawi Medical Journal

African Journals Online (AJOL)

Items 1 - 50 of 72 ... Archives: Malawi Medical Journal. Journal Home > Archives: Malawi Medical Journal. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 50 of 72 Items, 1 2 > >> ...
Archives: African Health Sciences

African Journals Online (AJOL)

Items 1 - 50 of 67 ... Archives: African Health Sciences. Journal Home > Archives: African Health Sciences. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 50 of 67 Items, 1 2 > >> ...
Archives: Health SA Gesondheid

African Journals Online (AJOL)

Items 1 - 42 of 42 ... Archives: Health SA Gesondheid. Journal Home > Archives: Health SA Gesondheid. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 42 of 42 Items. 2018 ...
Download - Open TG-GATEs | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...Download License Update History of This Database Site Policy | Contact Us Download - Open TG-GATEs | LSDB Archive ...
FTP archives for physics

International Nuclear Information System (INIS)

Trunec, D.; Brablec, A.; Kapicka, V.

1995-01-01

We have established archives for programs, data, papers etc. in physics (mainly for plasma physics). The archives are located at computer ftp.muni.cz in the directory pub/muni.cz/physics. These archives can be reached by anonymous FTP or by gopher server gopher.muni.cz (147.251.4.33). At the present time, programs for PC, cross sections for electrons, swarm parameters and rate constants stored are in the archives. We would like to collect the programs for calculations in physics (mainly for PC). We suppose that each program should have a testing example and some description. We would also like to collect physical constants and experimental or theoretical data (e.g. cross sections, swarm parameters and rate constants), which are important for other calculation or for comparison with the results of others studies. Interested scholars are invited to sent us their programs, data, preprints and reports for these archives. All files in the archives are in public domain and can be obtained using computer network Internet

Download - tRNADB-CE | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us tRNAD...f This Database Site Policy | Contact Us Download - tRNADB-CE | LSDB Archive ...
Archives: Mizan Law Review

African Journals Online (AJOL)

Items 1 - 21 of 21 ... Archives: Mizan Law Review. Journal Home > Archives: Mizan Law Review. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 21 of 21 Items. 2017. Vol 11, No 2 ...
Cytomorphology and immunohistochemistry of extrarenal rhabdoid tumor: A case report with review of literature

Directory of Open Access Journals (Sweden)

Manjula Jain

2011-01-01

Full Text Available Extrarenal rhabdoid tumor (ERRT is a rare, aggressive tumor with extremely poor prognosis. We report a case of ERRT with intraspinal extension in a 1.5-year-old child diagnosed by fine needle aspiration cytology (FNAC and immunohistochemistry. The child presented with a right lumbar region lump of two months duration. Ultrasound guided FNAC was performed and cell block was prepared. Smears were highly cellular and showed a dispersed population of large round cells having abundant pale eosinophillic cytoplasm, centrally to eccentrically placed nucleus with large prominent nucleoli. Immunohistochemistry was carried out on cell block which was positive for epithelial membrane antigen EMA and Vimentin. It was negative for leucocyte common antigen [LCA], wilms tumor 1, WT1, desmin and neuron specific enolaseNSE, thus ruling out other tumors like lymphoma, Wilms tumor, rhabdomyosarcoma, and neuroblastoma. A final diagnosis of ERRT was given. ERRT is an extremely rare tumor of retroperitoneal area; it should be included in the differential diagnosis of malignant round cell tumor in children. Cell block in this case is mandatory for putting up the panel of immunohistochemistry which can clinch the diagnosis of rhabdoid tumor and treatment can be started as early as possible.
Prolonged survival of a cat diagnosed with feline infectious peritonitis by immunohistochemistry.

Science.gov (United States)

Hugo, Timothy B; Heading, Kathryn L

2015-01-01

A 4-year-old, neutered male, British shorthair cat was presented with inappetence, vomiting, hyperproteinemia, and hyperglobulinemia. An exploratory celiotomy identified enlarged mesenteric lymph nodes. Immunohistochemistry of lymph node biopsies confirmed feline infectious peritonitis. This patient had a prolonged survival of 787 d after initial presentation.
Comparison of Chromogenic In Situ Hybridisation with Fluorescence In Situ Hybridisation and Immunohistochemistry for the Assessment of Her-2/neu Oncogene in Archival Material of Breast Carcinoma

International Nuclear Information System (INIS)

Pothos, Alexios; Plastira, Konstantina; Plastiras, Aris; Vlachodimitropoulos, Dimitrios; Goutas, Nikolaos; Angelopoulou, Roxani

2008-01-01

The successful treatment of breast cancer is dependent upon a number of complex factors. Her-2/neu gene amplification is known to be one of the most common genetic alterations associated with breast cancer and its accurate determination has become necessary for the selection of patients for trastuzumab therapy. The aim of this study was to prove the consistency of chromogenic in situ hybridisation (CISH) technique after analyzing the overexpression of the Her-2/neu proto-oncogene in 100 invasive breast carcinomas and by comparing CISH results with immunohistochemistry (IHC) and fluorescence in situ hybridisation (FISH). Moreover, it was done to evaluate the possible correlation of estrogen (ERs) and progesterone receptors (PRs), the proliferation marker Ki67 and the tumour suppressor gene p53 with HER-2/neu status of these breast carcinomas. Of the 100 breast carcinomas that were analysed, 22 cases showed HER-2/neu amplification, 66 cases showed no amplification, whereas 12 cases were non-interpretable in both assays (FISH and CISH). Consequently, the overall concordance between FISH and CISH was 100%. Additionally, it was observed that when HER-2/neu gene was overexpressed, there was an association with negative PRs and ERs status, negative p53 protein expression and high Ki67 labelling index. It is concluded that patients with tumours scoring 2+ with the CBE356 antibody (borderline immunohistochemistry-tested cases) would also benefit from CISH as it is shown to be highly accurate, practical and can be easily integrated into routine testing in any histopathology laboratory. Finally, CISH represents an important addition to the HER2 testing algorithm
Update History of This Database - dbQSNP | LSDB Archive [Life Science Database Archive metadata

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Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us dbQSNP Update History of This Database Date Update contents 2017/02/16 dbQSNP English archiv...e Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - dbQSNP | LSDB Archive ... ...e site is opened. 2002/10/23 dbQSNP (http://qsnp.gen.kyushu-u.ac.jp/) is opened. About This Database Databas
Fermilab History and Archives Project | Home

Science.gov (United States)

Special Events Early Users Meetings (1979 - 1989) The Tevatron Natural History Discoveries Technology Site Fermilab History and Archives Project Fermilab History and Archives Project Fermi National Accelerator Laboratory Home About the Archives History & Archives Online Request Contact Us Site Index
Soft Tissue Tumor Immunohistochemistry Update: Illustrative Examples of Diagnostic Pearls to Avoid Pitfalls.

Science.gov (United States)

Wei, Shi; Henderson-Jackson, Evita; Qian, Xiaohua; Bui, Marilyn M

2017-08-01

- Current 2013 World Health Organization classification of tumors of soft tissue arranges these tumors into 12 groups according to their histogenesis. Tumor behavior is classified as benign, intermediate (locally aggressive), intermediate (rarely metastasizing), and malignant. In our practice, a general approach to reaching a definitive diagnosis of soft tissue tumors is to first evaluate clinicoradiologic, histomorphologic, and cytomorphologic features of the tumor to generate some pertinent differential diagnoses. These include the potential line of histogenesis and whether the tumor is benign or malignant, and low or high grade. Although molecular/genetic testing is increasingly finding its applications in characterizing soft tissue tumors, currently immunohistochemistry still not only plays an indispensable role in defining tumor histogenesis, but also serves as a surrogate for underlining molecular/genetic alterations. Objective- To provide an overview focusing on the current concepts in the classification and diagnosis of soft tissue tumors, incorporating immunohistochemistry. This article uses examples to discuss how to use the traditional and new immunohistochemical markers for the diagnosis of soft tissue tumors. Practical diagnostic pearls, summary tables, and figures are used to show how to avoid diagnostic pitfalls. - Data were obtained from pertinent peer-reviewed English-language literature and the authors' first-hand experience as bone and soft tissue pathologists. - -The ultimate goal for a pathologist is to render a specific diagnosis that provides diagnostic, prognostic, and therapeutic information to guide patient care. Immunohistochemistry is integral to the diagnosis and management of soft tissue tumors.
Update History of This Database - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available CAGE TSS aggregation 」「 CAGE peaks 」 2015/12/07 FANTOM5 archive site is opened. (Archive V1) 2014/03/27 FANTOM5 ( http://fantom...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...5 Update History of This Database Date Update contents 2017/03/14 FANTOM5 English arch...escription Download License Update History of This Database Site Policy | Contact Us Update History of This Database - FANTOM5 | LSDB Archive ...
Prostate-specific membrane antigen PET imaging and immunohistochemistry in adenoid cystic carcinoma-@]@a preliminary analysis

Energy Technology Data Exchange (ETDEWEB)

Klein Nulent, Thomas J.W.; Es, Robert J.J. van [Utrecht Cancer Center, University Medical Center Utrecht, Department of Head and Neck Surgical Oncology, P.O. Box 85500, Utrecht (Netherlands); University Medical Center Utrecht, Department of Oral and Maxillofacial Surgery, Utrecht (Netherlands); Krijger, Gerard C.; Keizer, Bart de [University Medical Center Utrecht, Department of Radiology and Nuclear Medicine, Utrecht (Netherlands); Bree, Remco de [Utrecht Cancer Center, University Medical Center Utrecht, Department of Head and Neck Surgical Oncology, P.O. Box 85500, Utrecht (Netherlands); Willems, Stefan M. [University Medical Center Utrecht, Department of Pathology, Utrecht (Netherlands)

2017-09-15

Adenoid cystic carcinoma (AdCC) of the head and neck is an uncommon malignant epithelial tumour of the secretory glands. Many patients develop slowly growing local recurrence and/or distant metastasis, for which treatment options are limited. A retrospective analysis of 9 AdCC patients was conducted to analyse the visualization of AdCC on PSMA PET/CT and to investigate the expression of PSMA on primary, recurrent and metastatic AdCC tumour tissue using immunohistochemistry. Local recurrence occurred in six patients and eight developed distant metastasis. All PET/CTs depicted PSMA-ligand uptake. Four PSMA PET/CTs showed suspected residual disease, eight scans depicted uptake in areas suspected of distant metastasis. Median Maximum Standardized Uptake Value (SUV{sub max}) in local recurrent and distant metastatic AdCC was 2.52 (IQR 2.41-5.95) and 4.01 (IQR 2.66-8.71), respectively. All primary tumours showed PSMA expression on immunohistochemistry (5-90% expression), as well as all available specimens of local recurrence and distant metastases. PSMA PET/CT is able to detect and visualize local recurrent and distant metastatic AdCC. PSMA-specific targeting is supported by PSMA expression on immunohistochemistry. (orig.)
Data archiving in experimental physics

International Nuclear Information System (INIS)

Dalesio, L.R.; Watson, W. III; Bickley, M.; Clausen, M.

1998-01-01

In experimental physics, data is archived from a wide variety of sources and used for a wide variety of purposes. In each of these environments, trade-offs are made between data storage rate, data availability, and retrieval rate. This paper presents archive alternatives in EPICS, the overall archiver design and details on the data collection and retrieval requirements, performance studies, design choices, design alternatives, and measurements made on the beta version of the archiver
Update History of This Database - DMPD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us DMPD Update History of This Database Date Update contents 2010/03/29 DMPD English archive si....jp/macrophage/ ) is released. About This Database Database Description Download License Update History of Thi...s Database Site Policy | Contact Us Update History of This Database - DMPD | LSDB Archive ...
In Vitro Evaluation of Molecular Tumor Targets in Nuclear Medicine: Immunohistochemistry Is One Option, but Under Which Conditions?

Science.gov (United States)

Reubi, Jean Claude

2017-12-01

The identification of new molecular targets for diagnostic and therapeutic applications using in vitro methods is an important challenge in nuclear medicine. One such method is immunohistochemistry, increasingly popular because it is easy to perform. This review presents the case for conducting receptor immunohistochemistry to evaluate potential molecular targets in human tumor tissue sections. The focus is on the immunohistochemistry of G-protein-coupled receptors, one of the largest families of cell surface proteins, representing a major class of drug targets and thus playing an important role in nuclear medicine. This review identifies common pitfalls and challenges and provides guidelines on performing such immunohistochemical studies. An appropriate validation of the target is a prerequisite for developing robust and informative new molecular probes. © 2017 by the Society of Nuclear Medicine and Molecular Imaging.
Digital Forensics Formats: Seeking a Digital Preservation Storage Container Format for Web Archiving

Directory of Open Access Journals (Sweden)

Yunhyong Kim

2012-12-01

Full Text Available In this paper we discuss archival storage container formats from the point of view of digital curation and preservation, an aspect of preservation overlooked by most other studies. Considering established approaches to data management as our jumping off point, we selected seven container format attributes that are core to the long term accessibility of digital materials. We have labeled these core preservation attributes. These attributes are then used as evaluation criteria to compare storage container formats belonging to five common categories: formats for archiving selected content (e.g. tar, WARC, disk image formats that capture data for recovery or installation (partimage, dd raw image, these two types combined with a selected compression algorithm (e.g. tar+gzip, formats that combine packing and compression (e.g. 7-zip, and forensic file formats for data analysis in criminal investigations (e.g. aff – Advanced Forensic File format. We present a general discussion of the storage container format landscape in terms of the attributes we discuss, and make a direct comparison between the three most promising archival formats: tar, WARC, and aff. We conclude by suggesting the next steps to take the research forward and to validate the observations we have made.
Ethics and Truth in Archival Research

Science.gov (United States)

Tesar, Marek

2015-01-01

The complexities of the ethics and truth in archival research are often unrecognised or invisible in educational research. This paper complicates the process of collecting data in the archives, as it problematises notions of ethics and truth in the archives. The archival research took place in the former Czechoslovakia and its turbulent political…
Immunohistochemistry of LAMP-2 and adipophilin for phospholipidosis in liver and kidney in ketoconazole-treated mice.

Science.gov (United States)

Asaoka, Yoshiji; Togashi, Yuko; Imura, Naoko; Sai, Takafumi; Miyoshi, Tomoya; Miyamoto, Yohei

2013-09-01

Drug-induced phospholipidosis is an abnormal accumulation of phospholipids in the lysosomes following repeated administration of cationic amphiphilic drugs. Phospholipidosis is detected histopathologically as cytoplasmic vacuolation; however, it is difficult to distinguish from lipid accumulation since their morphological features are similar. In this study, we investigated the usefulness of immunohistochemistry for lysosome-associated membrane protein-2 (LAMP-2) and adipophilin, a membrane protein of cytosolic non-lysosomal lipid droplets, in the liver and kidneys of mice orally administered ketoconazole, an inducer of hepatic phospholipidosis. In 7-week-old mice administered ketoconazole (300 mg/kg/day) for 7 days, cytoplasmic vacuolation was histopathologically observed in centrilobular hepatocytes and proximal tubular epithelial cells under the fasted condition. The cytoplasmic vacuolation consisted of foamy vacuoles, which were revealed to be phospholipidosis-characteristic lamellar bodies by electron microscopy. Furthermore, lipid-like vacuoles were observed in the perilobular hepatocytes, and revealed to be lipid droplets by electron microscopy. In immunohistochemistry, the foamy vacuoles and lipid-like vacuoles were positive for LAMP-2 and adipophilin, respectively. These results indicate that immunohistochemistry for LAMP-2 and adipophilin could distinguish between phospholipidosis and lipid accumulation. Additionally, it could detect ketoconazole-induced phospholipidosis in the glycogen-rich livers of non-fasted mice. In conclusion, ketoconazole induced phospholipidosis in not only the liver but also the kidneys, and immunohistochemistry for LAMP-2 and adipophilin could be useful for the pathological evaluation of drug-induced phospholipidosis in mice. Crown Copyright © 2012. Published by Elsevier GmbH. All rights reserved.
Microwave processing of gustatory tissues for immunohistochemistry

Science.gov (United States)

Bond, Amanda; Kinnamon, John C.

2013-01-01

We use immunohistochemistry to study taste cell structure and function as a means to elucidate how taste receptor cells communicate with nerve fibers and adjacent taste cells. This conventional method, however, is time consuming. In the present study we used taste buds from rat circumvallate papillae to compare conventional immunohistochemical tissue processing with microwave processing for the colocalization of several biochemical pathway markers (PLCβ2, syntaxin-1, IP3R3, α-gustducin) and the nuclear stain, Sytox. The results of our study indicate that in microwave versus conventional immunocytochemistry: (1) fixation quality is improved; (2) the amount of time necessary for processing tissue is decreased; (3) antigen retrieval is no longer needed; (4) image quality is superior. In sum, microwave tissue processing of gustatory tissues is faster and superior to conventional immunohistochemical tissue processing for many applications. PMID:23473796
Discordance between imaging and immunohistochemistry in unilateral primary aldosteronism.

Science.gov (United States)

Nanba, Aya T; Nanba, Kazutaka; Byrd, James B; Shields, James J; Giordano, Thomas J; Miller, Barbara S; Rainey, William E; Auchus, Richard J; Turcu, Adina F

2017-12-01

Correct subtyping of primary aldosteronism (PA) is essential for good surgical outcomes. Adrenal vein sampling (AVS) and/or computed tomography (CT) are used for PA subclassification. Clinical and/or biochemical improvement after surgery, however, is not always achieved in patients with presumed unilateral PA. We aimed to identify the pitfalls in PA subclassification leading to surgical treatment failures. We retrospectively studied 208 patients who underwent adrenal vein sampling (AVS) for PA subclassification in a tertiary referral centre, between January 2009 and August 2016. Simultaneous bilateral AVS was performed before and after cosyntropin administration. We implemented immunohistochemistry for aldosterone synthase (CYP11B2) and 17α-hydroxylase/17,20 lyase (CYP17A1) in adrenal glands resected from patients without improvement of PA after surgical treatment and from those with limitations in AVS interpretation. Of 55 patients who underwent adrenalectomy, three (5.5%) had no improvement of PA. All three patients underwent partial adrenalectomy to remove a CT-detected nodule present on the same side with AVS lateralization. Immunohistochemistry revealed a CYP11B2-negative nodule in both cases available. All patients who underwent total adrenalectomy based on AVS lateralization benefitted from surgery, including three patients with unilateral unsuccessful AVS and aldosterone suppression in the catheterized side vs inferior vena cava. Radiographically identified adrenal nodules are not always a source of PA, even when ipsilateral with AVS lateralization. These data caution against reliance on imaging findings, either alone or in conjunction with AVS, to guide surgery for PA. © 2017 John Wiley & Sons Ltd.
Update History of This Database - SAHG | LSDB Archive [Life Science Database Archive metadata

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Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us SAHG Update History of This Database Date Update contents 2016/05/09 SAHG English archive si...te is opened. 2009/10 SAHG ( http://bird.cbrc.jp/sahg ) is opened. About This Database Database Description ...Download License Update History of This Database Site Policy | Contact Us Update History of This Database - SAHG | LSDB Archive ...
Update History of This Database - RMOS | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us RMOS Update History of This Database Date Update contents 2015/10/27 RMOS English archive si...12 RMOS (http://cdna01.dna.affrc.go.jp/RMOS/) is opened. About This Database Database Description Download License Update Hi...story of This Database Site Policy | Contact Us Update History of This Database - RMOS | LSDB Archive ...

A MySQL Based EPICS Archiver

International Nuclear Information System (INIS)

Slominski, Christopher

2009-01-01

Archiving a large fraction of the EPICS signals within the Jefferson Lab (JLAB) Accelerator control system is vital for postmortem and real-time analysis of the accelerator performance. This analysis is performed on a daily basis by scientists, operators, engineers, technicians, and software developers. Archiving poses unique challenges due to the magnitude of the control system. A MySQL Archiving system (Mya) was developed to scale to the needs of the control system; currently archiving 58,000 EPICS variables, updating at a rate of 11,000 events per second. In addition to the large collection rate, retrieval of the archived data must also be fast and robust. Archived data retrieval clients obtain data at a rate over 100,000 data points per second. Managing the data in a relational database provides a number of benefits. This paper describes an archiving solution that uses an open source database and standard off the shelf hardware to reach high performance archiving needs. Mya has been in production at Jefferson Lab since February of 2007.
A MySQL Based EPICS Archiver

Energy Technology Data Exchange (ETDEWEB)

Christopher Slominski

2009-10-01

Archiving a large fraction of the EPICS signals within the Jefferson Lab (JLAB) Accelerator control system is vital for postmortem and real-time analysis of the accelerator performance. This analysis is performed on a daily basis by scientists, operators, engineers, technicians, and software developers. Archiving poses unique challenges due to the magnitude of the control system. A MySQL Archiving system (Mya) was developed to scale to the needs of the control system; currently archiving 58,000 EPICS variables, updating at a rate of 11,000 events per second. In addition to the large collection rate, retrieval of the archived data must also be fast and robust. Archived data retrieval clients obtain data at a rate over 100,000 data points per second. Managing the data in a relational database provides a number of benefits. This paper describes an archiving solution that uses an open source database and standard off the shelf hardware to reach high performance archiving needs. Mya has been in production at Jefferson Lab since February of 2007.
License - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM....0 International . If you use data from this database, please be sure attribute this database as follows: FANTOM...se Database Description Download License Update History of This Database Site Policy | Contact Us License - FANTOM5 | LSDB Archive ...
License - Trypanosomes Database | LSDB Archive [Life Science Database Archive metadata

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Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us Trypanoso... Attribution-Share Alike 2.1 Japan . If you use data from this database, please be sure attribute this database as follows: Trypanoso...nse Update History of This Database Site Policy | Contact Us License - Trypanosomes Database | LSDB Archive ...
Online Archives

Directory of Open Access Journals (Sweden)

Julian D. Richards

2004-01-01

Full Text Available Online archives are of increasing importance in Archaeological Informatics, but like any new genre they prompt a number of questions. What is their relationship to publication? What should go in them? How should they be delivered and indexed? Can they be preserved? Whilst their delivery requires technology, we must also consider how that technology should best be employed in the service of our discipline. This article attempts to address some of these questions but it need not be read from start to finish. The links from this summary provide one fairly linear route through the text but each section is self-contained and can also be accessed directly from the Contents page. The problems posed by effective publication of archaeological fieldwork have exercised the profession for many decades. The issues raised go to the core of discussion of whether preservation by record is a valid concept, and indeed whether archaeological data exist. There are different schools of thought about the relationship between publication and archiving, but hopefully we can accept that data are recorded observations but still agree that they have a re-use value for re-examination and re-interpretation. Since the 1960s archaeology has experienced a publication crisis point. The scenario is familiar. Excavation is destruction; it is an unrepeatable experiment and the archaeologist has a professional obligation to make a full and accessible record of his/her observations. Yet full publication is increasingly expensive and difficult, and excavation monographs are read by few people, and bought by even fewer. In England the development of post-PPG16 fieldwork has exacerbated the problem by creating a mountain of unpublished grey literature and making the work of synthesis even harder; a similar situation exists in other countries. Meanwhile museum archives are also reaching breaking point; most are running out of storage space, few can provide facilities for access, and
Update History of This Database - SSBD | LSDB Archive [Life Science Database Archive metadata

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Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us SSBD Update History of This Database Date Update contents 2016/07/25 SSBD English archive si...tion Download License Update History of This Database Site Policy | Contact Us Update History of This Database - SSBD | LSDB Archive ... ...te is opened. 2013/09/03 SSBD ( http://ssbd.qbic.riken.jp/ ) is opened. About This Database Database Descrip
The Comparison Study of Six University Archives

Directory of Open Access Journals (Sweden)

Chun-Fen Liu

2004-03-01

Full Text Available The university archives is not only the extension of a building, but also includes the archival records, archivists and equipments. The university archives is the historical memory of a university, which could let people to predict the future by reviewing the past. The university archives has abundant collections, both teachers and students can review history of this university. This paper mainly compares six university archives of Taiwan, and the interviewing method is used in this research. After comparison of the six university archives, we have found the six university archives have different organizational structures, budgets, and functions. Finally the authors propose some suggestions.[Article content in Chinese
Archives Library Information Center

Data.gov (United States)

National Archives and Records Administration — ALIC is an online library catalog of books, periodicals, and other materials contained in Archives I and II and book collections located in other facilities.
The Ethics of Archival Research

Science.gov (United States)

McKee, Heidi A.; Porter, James E.

2012-01-01

What are the key ethical issues involved in conducting archival research? Based on examination of cases and interviews with leading archival researchers in composition, this article discusses several ethical questions and offers a heuristic to guide ethical decision making. Key to this process is recognizing the person-ness of archival materials.…
GRIP Database original data - GRIPDB | LSDB Archive [Life Science Database Archive metadata

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Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us GRI...PDB GRIP Database original data Data detail Data name GRIP Database original data DOI 10....18908/lsdba.nbdc01665-006 Description of data contents GRIP Database original data It consists of data table...s and sequences. Data file File name: gripdb_original_data.zip File URL: ftp://ftp.biosciencedbc.jp/archive/gripdb/LATEST/gri...e Database Description Download License Update History of This Database Site Policy | Contact Us GRIP Database original data - GRIPDB | LSDB Archive ...
Dynamic Data Management Based on Archival Process Integration at the Centre for Environmental Data Archival

Science.gov (United States)

Conway, Esther; Waterfall, Alison; Pepler, Sam; Newey, Charles

2015-04-01

In this paper we decribe a business process modelling approach to the integration of exisiting archival activities. We provide a high level overview of existing practice and discuss how procedures can be extended and supported through the description of preservation state. The aim of which is to faciliate the dynamic controlled management of scientific data through its lifecycle. The main types of archival processes considered are: • Management processes that govern the operation of an archive. These management processes include archival governance (preservation state management, selection of archival candidates and strategic management) . • Operational processes that constitute the core activities of the archive which maintain the value of research assets. These operational processes are the acquisition, ingestion, deletion, generation of metadata and preservation actvities, • Supporting processes, which include planning, risk analysis and monitoring of the community/preservation environment. We then proceed by describing the feasability testing of extended risk management and planning procedures which integrate current practices. This was done through the CEDA Archival Format Audit which inspected British Atmospherics Data Centre and National Earth Observation Data Centre Archival holdings. These holdings are extensive, comprising of around 2PB of data and 137 million individual files which were analysed and characterised in terms of format based risk. We are then able to present an overview of the risk burden faced by a large scale archive attempting to maintain the usability of heterogeneous environmental data sets. We conclude by presenting a dynamic data management information model that is capable of describing the preservation state of archival holdings throughout the data lifecycle. We provide discussion of the following core model entities and their relationships: • Aspirational entities, which include Data Entity definitions and their associated
Archives: Medical Journal of Zambia

African Journals Online (AJOL)

Items 1 - 39 of 39 ... Archives: Medical Journal of Zambia. Journal Home > Archives: Medical Journal of Zambia. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 39 of 39 Items ...
Archives: Annals of Pediatric Surgery

African Journals Online (AJOL)

Items 1 - 32 of 32 ... Archives: Annals of Pediatric Surgery. Journal Home > Archives: Annals of Pediatric Surgery. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 32 of 32 Items ...
Archives: Town and Regional Planning

African Journals Online (AJOL)

Items 1 - 12 of 12 ... Archives: Town and Regional Planning. Journal Home > Archives: Town and Regional Planning. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 12 of 12 ...
Archives: Egyptian Journal of Biology

African Journals Online (AJOL)

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Archives: Pan African Medical Journal

African Journals Online (AJOL)

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Archives: Orient Journal of Medicine

African Journals Online (AJOL)

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Archives: Libyan Journal of Medicine

African Journals Online (AJOL)

Items 1 - 23 of 23 ... Archives: Libyan Journal of Medicine. Journal Home > Archives: Libyan Journal of Medicine. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 23 of 23 Items ...
Archives: African Crop Science Journal

African Journals Online (AJOL)

Items 1 - 50 of 99 ... Archives: African Crop Science Journal. Journal Home > Archives: African Crop Science Journal. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 50 of 99 ...
Archives: African Crop Science Journal

African Journals Online (AJOL)

Items 51 - 99 of 99 ... Archives: African Crop Science Journal. Journal Home > Archives: African Crop Science Journal. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 51 - 99 of 99 ...

Utility of CK7 and CK20 immunohistochemistry in the detection of synchronous breast and colon carcinoma in a pleural effusion: a case report and supporting survey of archival material

DEFF Research Database (Denmark)

Stopyra, G A; Warhol, M J; Multhaupt, H A

2001-01-01

, respectively. An immunohistochemical survey of archival breast and colon primary and metastatic carcinomas confirmed the established CK7+/CK20- phenotype of breast and CK7-/CK20+ phenotype of colon primary carcinomas, and the maintenance of this phenotype in metastases thereof. A survey of benign and malignant...
Accuracy of HER2 status determination on breast core-needle biopsies (immunohistochemistry, FISH, CISH and SISH vs FISH).

Science.gov (United States)

Arnould, Laurent; Roger, Pascal; Macgrogan, Gaëtan; Chenard, Marie-Pierre; Balaton, André; Beauclair, Sophie; Penault-Llorca, Frederique

2012-05-01

Preoperative breast cancer diagnosis on core biopsies has become a standard of care in many countries. Controversies exist concerning the accuracy of HER2 testing on biopsies as compared with surgical specimens, and few data exist concerning the use of emerging technologies such as bright-field in-situ hybridization in such a setting. A French multicenter, cross-sectional, histopathological study assessed the concordance of HER2 status determined by immunohistochemistry and silver (SISH) or chromogenic in-situ hybridization (CISH) on core-needle biopsies with HER2 status determined by fluorescence in-situ hybridization (FISH) on surgical specimens. The concordance between biopsy and operative results was also assessed for each method. We studied 260 breast tumors from 24 centers between April 2003 and August 2009. Excellent concordance (κ: 0.92-0.97) was shown between immunohistochemistry and FISH with low discordance rates (2-4%), high specificity (97-98%) and sensitivity values (95-99%), with no significant difference according to the immunohistochemistry interpretation guidelines used. The correlation between SISH and CISH on biopsies and FISH on surgical samples was strong (κ: 0.96 and 0.94, respectively), with no significant difference between false negative rates or sensitivity and specificity values (2 and 5%, 99 and 96%, 98 and 98%, respectively). Whatever the evaluation technique, excellent concordance between biopsies and surgical specimens was observed (κ ≥ 0.97; discordance rates between 1 and 2%), with high sensitivity (98-99%) and specificity (98-100%). Based on these results, when FISH cannot be used, SISH and/or CISH could be proposed as an alternative method to determine HER2 status and to confirm any ambiguous immunohistochemistry results, either for preoperative percutaneous biopsies or for surgical specimens. They could also be used for quality controls and immunohistochemistry calibration.
Tomorrow’s Universities and the Seven Pillars of the Knowledge Revolution

Directory of Open Access Journals (Sweden)

Ismail Serageldin

2013-09-01

Full Text Available The emerging Knowledge Revolution goes beyond the changing technologies and the challenges and opportunities they create to include the structure of knowledge and how it is transmitted inter-generationally and across countries. There are seven major features of that profound transformation, which I call “The Seven Pillars of the New Knowledge Revolution”. These are: (i Parsing, Life & Organization; (ii Image & Text; (iii Humans & Machines; (iv Complexity & Chaos; (v Computation & Research; (vi Convergence & Transformation; and (vii Pluridisciplinarity & Policy. This diagnosis has profound implications on how one should think about the design and management of our institutions of learning, starting not only with universities, but also the school system, as well as our research institutions (whether in universities or in public and private labs, and the supporting institutions of knowledge (like museums, libraries and archives. Radical proposals are advanced for the content, method, participants and organizational setting of education, as well as the role of the University as mediator of transitions, its relationship with society and economy, as well as its physical presence, governance structure and the values it should promote. Core functions and curricula for the future, along with the possibility of a global university consortium, are discussed.
Outlook: The Next Twenty Years

Energy Technology Data Exchange (ETDEWEB)

Murayama, Hitoshi

2003-12-07

I present an outlook for the next twenty years in particle physics. I start with the big questions in our field, broken down into four categories: horizontal, vertical, heaven, and hell. Then I discuss how we attack the bigquestions in each category during the next twenty years. I argue for a synergy between many different approaches taken in our field.
Archives: African Journal of Urology

African Journals Online (AJOL)

Items 1 - 50 of 66 ... Archives: African Journal of Urology. Journal Home > Archives: African Journal of Urology. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 50 of 66 Items, 1 2 ...
Archives: Jos Journal of Medicine

African Journals Online (AJOL)

Items 1 - 18 of 18 ... Archives: Jos Journal of Medicine. Journal Home > Archives: Jos Journal of Medicine. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 18 of 18 Items. 2017 ...
Archives: Edo Journal of Counselling

African Journals Online (AJOL)

Items 1 - 6 of 6 ... Archives: Edo Journal of Counselling. Journal Home > Archives: Edo Journal of Counselling. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 6 of 6 Items. 2011 ...
Archives: les cahiers du cread

African Journals Online (AJOL)

Items 1 - 24 of 24 ... Archives: les cahiers du cread. Journal Home > Archives: les cahiers du cread. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 24 of 24 Items. 2016 ...
Archives: Annals of Modern Education

African Journals Online (AJOL)

Items 1 - 8 of 8 ... Archives: Annals of Modern Education. Journal Home > Archives: Annals of Modern Education. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 8 of 8 Items. 2016 ...
NASA's Astrophysics Data Archives

Science.gov (United States)

Hasan, H.; Hanisch, R.; Bredekamp, J.

2000-09-01

The NASA Office of Space Science has established a series of archival centers where science data acquired through its space science missions is deposited. The availability of high quality data to the general public through these open archives enables the maximization of science return of the flight missions. The Astrophysics Data Centers Coordinating Council, an informal collaboration of archival centers, coordinates data from five archival centers distiguished primarily by the wavelength range of the data deposited there. Data are available in FITS format. An overview of NASA's data centers and services is presented in this paper. A standard front-end modifyer called `Astrowbrowse' is described. Other catalog browsers and tools include WISARD and AMASE supported by the National Space Scince Data Center, as well as ISAIA, a follow on to Astrobrowse.
Download - PGDBj - Ortholog DB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available e Description Download License Update History of This Database Site Policy | Contact Us Download - PGDBj - Ortholog DB | LSDB Archive ... ...List Contact us PGDBj - Ortholog DB Download First of all, please read the license of this database. Data na...switchLanguage; BLAST Search Image Search Home About Archive Update History Data
SODA: Smart Objects, Dumb Archives

Science.gov (United States)

Nelson, Michael L.; Maly, Kurt; Zubair, Mohammad; Shen, Stewart N. T.

2004-01-01

We present the Smart Object, Dumb Archive (SODA) model for digital libraries (DLs). The SODA model transfers functionality traditionally associated with archives to the archived objects themselves. We are exploiting this shift of responsibility to facilitate other DL goals, such as interoperability, object intelligence and mobility, and heterogeneity. Objects in a SODA DL negotiate presentation of content and handle their own terms and conditions. In this paper we present implementations of our smart objects, buckets, and our dumb archive (DA). We discuss the status of buckets and DA and how they are used in a variety of DL projects.
Implementation of immunohistochemistry on frozen ear notch tissue samples in diagnosis of bovine viral diarrhea virus in persistently infected cattle

Directory of Open Access Journals (Sweden)

Bedeković Tomislav

2011-12-01

Full Text Available Abstract Background Bovine viral diarrhea is a contagious disease of domestic and wild ruminants and one of the most economically important diseases in cattle. Bovine viral diarrhea virus belongs to the genus Pestivirus, within the family Flaviviridae. The identification and elimination of the persistently infected animals from herds is the initial step in the control and eradication programs. It is therefore necessary to have reliable methods for diagnosis of bovine viral diarrhea virus. One of those methods is immunohistochemistry. Immunohistochemistry on formalin fixed, paraffin embedded tissue is a routine technique in diagnosis of persistently infected cattle from ear notch tissue samples. However, such technique is inappropriate due to complicated tissue fixation process and it requires more days for preparation. On the contrary, immunohistochemistry on frozen tissue was usually applied on organs from dead animals. In this paper, for the first time, the imunohistochemistry on frozen ear notch tissue samples was described. Findings Seventeen ear notch tissue samples were obtained during the period 2008-2009 from persistently infected cattle. Samples were fixed in liquid nitrogen and stored on -20°C until testing. Ear notch tissue samples from all persistently infected cattle showed positive results with good section quality and possibility to determinate type of infected cells. Conclusions Although the number of samples was limited, this study indicated that immunohistochemistry on formalin fixed paraffin embedded tissue can be successfully replaced with immunohistochemistry on frozen ear notch tissue samples in diagnosis of persistently infected cattle.
Archival Education in Scandinavian Countries

Directory of Open Access Journals (Sweden)

Muhammet Hanefi Kutluoğlu

2008-03-01

Full Text Available Every country has responsibilities to provide the necessary personnel needed for their archival inheritance by education. Education can be shaped through tradition, historical inheritance and scientifi c necessities by defi ning the right educational method. Scandinavian countries have determined different education models based on their tradition, historical inheritance and requirements. In this article we focused on the formation of archival tradition, application of archival education in Scandinavian countries and the infl uence of the developments taking place in Europe on these countries. The relation between the archival education in European and Scandinavian countries is evaluated through a comparative method, and similarities to other countries are also evaluated. Finally, the present situation of archival education and the measures needed in this fi eld are taken into consideration.
Digital Preservation at the Swiss Federal Archives

International Nuclear Information System (INIS)

Ohnesorge, Krystyna

2012-01-01

The Swiss Federal Archives (SFA) archives Swiss government data when it is no longer in use. The SFA is responsible for advising, inspecting and issuing directives in records management and archiving services in offices, agencies and institutions subjected to the Federal Act on Archiving; as well as archiving and disseminating records and data of archival value. With regard to RWM, it thus in fact is an additional regulator. The conceptual basis for digital archiving at the SFA is based on the ISO OAIS Open Archival Information System Reference Model (ISO 14721:2003). The SFA use a process-orientated approach. The SFA and the Federal Office decide jointly which documents and data are to be archived. Archive-worthy documents and data are selected on the basis of a systematic appraisal. Wherever possible this should be carried out pro-actively - before the documents are actually created - based on an indexing or classification system. If there is clarity, people will know what data - and metadata - to keep for the submission. The submission is split into several stages, from appraisal to the conclusion of the submission. Information is never changed once it is archived, except that it carries out conservation measures. New information is a new submission. The sustainable information management is a core expertise of national archives. The SFA preserves digital records and data and is responsible for their secure and appropriate safe-keeping, description and dissemination. For the archiving of relational databases (e.g. Microsoft Access, Oracle and SQL Server), the SFA have developed a format known as SIARD (Software Independent Archiving of Relational Databases). SIARD is an open standard and is supported by the SIARD Suite application, which can be used to convert relational databases into SIARD format. The SIARD Suite is now in use worldwide (over 170 downloads). The SFA distribute the SIARD Suite free of charge in conformity with the license agreement. Currently
Taxon (Viridiplantae) - PGDBj - Ortholog DB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available of This Database Site Policy | Contact Us Taxon (Viridiplantae) - PGDBj - Ortholog DB | LSDB Archive ... ...List Contact us PGDBj - Ortholog DB Taxon (Viridiplantae) Data detail Data name Taxon (Viridiplantae) DOI 10...switchLanguage; BLAST Search Image Search Home About Archive Update History Data
Taxon (Cyanobacteria) - PGDBj - Ortholog DB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available of This Database Site Policy | Contact Us Taxon (Cyanobacteria) - PGDBj - Ortholog DB | LSDB Archive ... ...List Contact us PGDBj - Ortholog DB Taxon (Cyanobacteria) Data detail Data name Taxon (Cyanobacteria) DOI 10...switchLanguage; BLAST Search Image Search Home About Archive Update History Data
Toward a Greater Discourse: Issues in Religious Archives

Directory of Open Access Journals (Sweden)

Robert Presutti

2010-06-01

Full Text Available The topic of religious archives, a catalyst of much discussion in archival literature, has traditionally been overlooked within the discourse of the American Theological Library Association (ATLA. This essay provides a survey analysis of three pertinent issues in religious archives with the intention of generating a wider discussion on religious archives within ATLA. These issues include the role of graduate archival education, the effects of religious faith on both the archival record and the individual archivist, and the idea of a theology of archives. An extended review of the contributions of James O’Toole to the discussion of religious archives is utilized.
Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer

NARCIS (Netherlands)

de Jong, Andrea E.; van Puijenbroek, Marjo; Hendriks, Yvonne; Tops, Carli; Wijnen, Juul; Ausems, Margreet G. E. M.; Meijers-Heijboer, Hanne; Wagner, Anja; van Os, Theo A. M.; Bröcker-Vriends, Annette H. J. T.; Vasen, Hans F. A.; Morreau, Hans

2004-01-01

Immunohistochemistry (IHC) and microsatellite instability (MSI) analysis can be used to identify patients with a possible DNA mismatch repair defect [hereditary nonpolyposis colorectal carcinoma (HNPCC)]. The Bethesda criteria have been proposed to select families for determination of MSI. The aims
The prognostic and predictive value of sstr{sub 2}-immunohistochemistry and sstr{sub 2}-targeted imaging in neuroendocrine tumors

Energy Technology Data Exchange (ETDEWEB)

Brunner, Philippe [University Hospital Basel, Institute of Pathology (Switzerland); University Hospital Basel, Institute of Nuclear Medicine (Switzerland); Joerg, Ann-Catherine; Mueller-Brand, Jan [University Hospital Basel, Institute of Nuclear Medicine (Switzerland); Glatz, Katharina; Bubendorf, Lukas [University Hospital Basel, Institute of Pathology (Switzerland); Radojewski, Piotr; Umlauft, Maria; Spanjol, Petar-Marko; Krause, Thomas; Dumont, Rebecca A.; Walter, Martin A. [University Hospital Bern, Institute of Nuclear Medicine (Switzerland); Marincek, Nicolas [University Hospital Basel, Institute of Nuclear Medicine (Switzerland); University Hospital Bern, Institute of Nuclear Medicine (Switzerland); Maecke, Helmut R. [University Hospital Basel, Division of Radiological Chemistry (Switzerland); Briel, Matthias [University Hospital Basel, Basel Institute for Clinical Epidemiology and Biostatistics (Switzerland); McMaster University, Department of Clinical Epidemiology and Biostatistics, Hamilton (Canada); Schmitt, Anja; Perren, Aurel [University Bern, Institute of Pathology, Bern (Switzerland)

2017-03-15

Our aim was to assess the prognostic and predictive value of somatostatin receptor 2 (sstr{sub 2}) in neuroendocrine tumors (NETs). We established a tissue microarray and imaging database from NET patients that received sstr{sub 2}-targeted radiopeptide therapy with yttrium-90-DOTATOC, lutetium-177-DOTATOC or alternative treatment. We used univariate and multivariate analyses to identify prognostic and predictive markers for overall survival, including sstr{sub 2}-imaging and sstr{sub 2}-immunohistochemistry. We included a total of 279 patients. In these patients, sstr{sub 2}-immunohistochemistry was an independent prognostic marker for overall survival (HR: 0.82, 95 % CI: 0.67 - 0.99, n = 279, p = 0.037). In DOTATOC patients, sstr{sub 2}-expression on immunohistochemistry correlated with tumor uptake on sstr{sub 2}-imaging (n = 170, p < 0.001); however, sstr{sub 2}-imaging showed a higher prognostic accuracy (positive predictive value: +27 %, 95 % CI: 3 - 56 %, p = 0.025). Sstr{sub 2}-expression did not predict a benefit of DOTATOC over alternative treatment (p = 0.93). Our results suggest sstr{sub 2} as an independent prognostic marker in NETs. Sstr{sub 2}-immunohistochemistry correlates with sstr{sub 2}-imaging; however, sstr{sub 2}-imaging is more accurate for determining the individual prognosis. (orig.)

Phenome data - High-sugar stress - DGBY | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...s.zip File size: 90KB File name: Original file: High-sugar_stress.xls File URL: ftp://ftp.biosciencedbc.jp/archive/dgby/LATEST/Hi... Center for Protein Sequences） About This Database Database Description Download License Update History of Thi...s Database Site Policy | Contact Us Phenome data - High-sugar stress - DGBY | LSDB Archive ... ...List Contact us DGBY Phenome data - High-sugar stress Data detail Data name Phenome data - High-sugar stress
Twenty Practices of an Entrepreneurial University

DEFF Research Database (Denmark)

Gjerding, Allan Næs; Wilderom, Celeste P.M.; Cameron, Shona P.B.

2006-01-01

studies twenty organisational practices against which a University's entrepreneurship can be measured. These twenty practices or factors in effect formed the basis for an entrepreneurship audit. During a series of interviews, the extent to which the universities are seen as entrepreneurial...
Chromogenic in situ hybridization for Her-2/neu-oncogene in breast cancer: comparison of a new dual-colour chromogenic in situ hybridization with immunohistochemistry and fluorescence in situ hybridization.

Science.gov (United States)

Mayr, Doris; Heim, Sibylle; Weyrauch, Kerstin; Zeindl-Eberhart, Evelyn; Kunz, Anne; Engel, Jutta; Kirchner, Thomas

2009-12-01

Her-2/neu testing is used as a marker for Herceptin therapy. The aim was to investigate new dual-colour chromogenic in situ hybridization (CISH), in a large number of breast carcinomas (n = 205) with DNA-specific dual-colour probes (ZytoVision, Bremerhaven, Germany) and to compare the results with immunohistochemistry (n = 205) and fluorescence in situ hybridization (FISH) (n = 129). Paraffin-embedded tissue of 205 patients was used. After immunohistochemistry with a focus on immunohistochemically uncertain cases, Her-2/neu amplification using dual-colour CISH (ZytoVision) was analysed. Validation by FISH was performed. The results were: immunohistochemistry, 27.8% with strong expression, 53.7% with uncertain overexpression and 18.5% with no expression; FISH, 25.6% amplified and 74.4% negative; CISH, 35.6% amplified, 62.9% negative and 1.5% not evaluable. Comparison of immunohistochemistry with CISH: CISH negative in 100% with immunohistochemistry 0/1+, amplified in 82.5% with immunohistochemistry 3+; 5.9% contradictory results: 4.4% immunohistochemistry 3+ and negative by CISH, 1.5% negative in immunohistochemistry but amplified by CISH; FISH (129 cases), 8.5% contradictory results to immunohistochemistry, 6.2% immunohistochemistry 3+ and negative by FISH, 2.3% negative by immunohistochemistry and amplified by FISH; comparison of CISH and FISH, 94.6% same results, 3.9% different ones, 1.6% CISH not analysable. CISH, using dual-colour probes (ZytoVision) is as good as FISH for Her-2/neu analysis. The few discrepant results are likely to be caused by polysomy or tumour heterogeneity.
Internet FAQ Archives - Online Education - faqs.org

Science.gov (United States)

faqs.org Internet FAQ Archives - Online Education faqs.org faqs.org - Internet FAQ Archives Internet FAQ Archives Online Education Internet RFC Index Usenet FAQ Index Other FAQs Documents Tools IFC Rated FAQs Internet RFC/STD/FYI/BCP Archives The Internet RFC series of documents is also available from
Efficiency of PR communication in establishing links between archives and students: case study of the State Archives in Zadar

Directory of Open Access Journals (Sweden)

Goran Pavelin

2013-03-01

Full Text Available The aim of the paper is to highlight the changing role of archives and to use the case study to indicate the lacking communication with students due to the absence of PR activities, as well as to point to the difficulties of access to digital archival materials needed for student research. Using PR strategies the archives can sensitise the public for its material through different public programmes, exhibitions and fostering goodmedia relations. The archives try to develop good relations with target groups, in this case with students as potential users, taking into consideration their research needs and materials they are interested in. Research findings on student needs for archival data are extremely rare, even in recent American research. Therefore, we conducted this research using a questionnaire for students of four departments of the University of Zadar (geography, history, art history, tourism and communication, who were users of the State Archives in Zadar. The research results show whether the subjects use archival material, for what purposes, and what other resources they used prior to archival material. It also provides information on the level of familiarity with online archival material and use of web pages with archival resources. We can conclude that the students in Zadar are not well acquainted with the digital resources and use them rarely for their research purposes. The situation can be improved by having the State Archives in Zadar take a more proactive role in identifying target groups of students, their user profiles, difficulties they face, and by allowing a more flexible access to archival material. In addition to goo d relations with the Department of Information Sciences, the Archives should foster links with other departments and include them in planning and implementation of their programmes.
Update History of This Database - fRNAdb | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us fRNAdb Update History of This Database Date Update contents 2016/03/29 fRNAdb English archiv...on Download License Update History of This Database Site Policy | Contact Us Update History of This Database - fRNAdb | LSDB Archive ... ...e site is opened. 2006/12 fRNAdb ( http://www.ncrna.org/ ) is opened. About This Database Database Descripti
Sample ontology, GOstat and ontology term enrichment - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM....biosciencedbc.jp/archive/fantom5/datafiles/LATEST/extra/Ontology/ File size: 1.8 MB Simple search URL - Dat...t Us Sample ontology, GOstat and ontology term enrichment - FANTOM5 | LSDB Archive ...
IN SITU IMMUNE RESPONSE EVALUATION VIA IMMUNOHISTOCHEMISTRY IN SKIN BIOPSIES FROM PATIENTS AFFECTED BY AUTOIMMUNE BLISTERING DISEASES

Directory of Open Access Journals (Sweden)

Ana Maria Abreu Velez

2013-11-01

Full Text Available Introduction: The in situ immune response in skin biopsies from patients affected by autoimmune skin blistering diseases (ABD is not well characterized. Aim: Our investigation attempts to immunophenotype cells in lesional skin in several ABD, utilizing immunohistochemistry (ICH. Methods: We tested by IHC for CD4, CD8, CD19, CD20, CD45, CD56/NCAM, PAX-5, granzyme B, myeloperoxidase, neutrophil elastase, LAT and ZAP-70 in patients affected by ABD. We tested 30 patients with endemic pemphigus foliaceus (EPF, 15 controls from the EPF endemic area, and 15 biopsies from healthy controls from the USA. We also tested archival biopsies from patients with selected ABD, including 30 patients with bullous pemphigoid, 20 with pemphigus vulgaris, 8 with pemphigus foliaceus and 14 with dermatitis herpetiformis. Results: We found a predominantly CD8 positive/CD45 positive T cell infiltrate in all ABD. Our skin biopsies demonstrated consistently positive staining for myeloperoxidase, but negative staining for neutrophil elastase. Most ABD biopsies displayed negative staining for CD4 and B cell markers; natural killer cell markers were also rarely seen. ZAP-70 and LAT were frequently detected. In El Bagre-EPF, a significant fragmentation of T cells in lesional skin was noted, as well as autoreactivity to lymph nodes. Conclusions: The documented T cell and myeloperoxidase staining are indicative of the role of T lymphocytes and neutrophils in lesional biopsies in patients with ABD, in addition to previously documented deposition of B cells, immunoglobulins and complement in situ. In El Bagre-EPF, T cells could also target lymph nodes; however, further studies are needed to confirm this possibility.
Update History of This Database - RMG | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us RMG Update History of This Database Date Update contents 2016/08/22 The contact address is c...dna.affrc.go.jp/ ) is opened. About This Database Database Description Download License Update Hi...story of This Database Site Policy | Contact Us Update History of This Database - RMG | LSDB Archive ... ... URL of the portal site is changed. 2013/08/07 RMG archive site is opened. 2002/09/25 RMG ( http://rmg.rice.
Update History of This Database - DGBY | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us DGBY Update History of This Database Date Update contents 2014/10/20 The URL of the portal s...aro.affrc.go.jp/yakudachi/yeast/index.html ) is opened. About This Database Database Description Download License Update Hi...story of This Database Site Policy | Contact Us Update History of This Database - DGBY | LSDB Archive ... ... Expression of attribution in License is updated. 2012/03/08 DGBY English archive site is opened. 2006/10/02
The FARC fuel archive of VVER

International Nuclear Information System (INIS)

Zizin, M.N.; Parfenova, N.A.; Proselkov, V.N.; Shishkov, L.K.

1998-01-01

The principles of organisation are explained and the structure of the FARC fuel archive for VVER reactors is described. The objective of the archive is accumulation of fuel data, data storage and obtaining the fuel using characteristics. The working version of fuel archive on 01.07.98 is realised, in which the data tables for fuel assemblies for 169 VVER-440 cycles and 35 VVER-1000 cycles are stored. There are two different versions of fuel archive - for VVER-440 (FARC) and for VVER-1000 (FARC1000). A structure of some tables and the texts of programs for them differ. The algorithms and codes for checking integrity, reasonableness and reliability of fuel archive data are developed. (author)
Pathway enrichment and co-expression cluster analysis - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...lusters File URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/phase1.3/extra/Co-expression_clusters...ite Policy | Contact Us Pathway enrichment and co-expression cluster analysis - FANTOM5 | LSDB Archive ...
Archival Information Management System.

Science.gov (United States)

1995-02-01

management system named Archival Information Management System (AIMS), designed to meet the audit trail requirement for studies completed under the...are to be archived to the extent that future reproducibility and interrogation of results will exist. This report presents a prototype information
Update History of This Database - TogoTV | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us TogoTV Update History of This Database Date Update contents 2017/05/12 TogoTV English archiv...ription Download License Update History of This Database Site Policy | Contact Us Update History of This Database - TogoTV | LSDB Archive ... ...e site is opened. 2007/07/20 TogoTV ( http://togotv.dbcls.jp/ ) is opened. About This Database Database Desc
Update History of This Database - ConfC | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us ConfC Update History of This Database Date Update contents 2016/09/20 ConfC English archive ...tion Download License Update History of This Database Site Policy | Contact Us Update History of This Database - ConfC | LSDB Archive ... ...site is opened. 2005/05/01 ConfC (http://mbs.cbrc.jp/ConfC/) is opened. About This Database Database Descrip
Update History of This Database - tRNADB-CE | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us tRNAD...11/08/25 License is updated. 2010/03/29 tRNADB-CE English archive site is opened. 2008/7/1 tRNADB-CE( http:/...Download License Update History of This Database Site Policy | Contact Us Update History of This Database - tRNADB-CE | LSDB Archive ...
Costs of Archival Storage

DEFF Research Database (Denmark)

Nielsen, Anders Bo; Thirifays, Alex; Kejser, Ulla Bøgvad

2012-01-01

to determine the costs of establishing and maintaining a preservation solution destined for long-term preservation of digital materials and to develop a tool capable of doing this operation. In order to fulfill the purposes, the project employed a combination of own and external experience as well as the OAIS......This paper presents an analysis of the cost of archival storage. The study is part of a project conducted by The Danish National Archives, The Royal Library, and The State and University Library to develop a generic cost model for digital preservation (CMDP). The purposes of the study were...... Reference Model as a framework to fully understand and identify the cost critical activities of bit-preservation as described in Archival Storage. We found that the costs of Archival Storage are obviously closely linked to the data volume, but also to the required preservation quality, especially...
Protein (Viridiplantae) - PGDBj - Ortholog DB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available ase Description Download License Update History of This Database Site Policy | Contact Us Protein (Viridiplantae) - PGDBj - Ortholog DB | LSDB Archive ... ...List Contact us PGDBj - Ortholog DB Protein (Viridiplantae) Data detail Data name Protein (Viridiplantae) DO...switchLanguage; BLAST Search Image Search Home About Archive Update History Data
License - Plabrain DB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us Plabrain... Alike 2.1 Japan . If you use data from this database, please be sure attribute this database as follows: Plabrain...of this database (http://dbarchive.lifesciencedb.jp/english/en/plabrain-db/desc.html) in the article or pape...se Description Download License Update History of This Database Site Policy | Contact Us License - Plabrain DB | LSDB Archive ...
Quantification in immunohistochemistry: the measurement of the ratios of collagen types I and II

NARCIS (Netherlands)

van der Loos, C. M.; Marijianowski, M. M.; Becker, A. E.

1994-01-01

Quantitative techniques in immunohistochemistry are needed, but they are rarely applied because of doubtful reproducibility. We have developed a method for the detection of collagen types I and III in situ. The method applied was a two-step immuno-alkaline phosphatase technique with visualization of

Archiving Electronic Publications - a Librarian's Point of View

Science.gov (United States)

Grothkopf, U.

Archiving electronic journals is complex. There are many questions: Who is responsible for archiving? What is archived? How many copies should be archived. How can one ensure the integrity of electronic documents? How can access be maintained? Technology will provide some answers. Electronic archives will require periodic refreshing and migration to new technology. Many factors remain unknown at present.
A Background to Motion Picture Archives.

Science.gov (United States)

Fletcher, James E.; Bolen, Donald L., Jr.

The emphasis of archives is on the maintenance and preservation of materials for scholarly research and professional reference. Archives may be established as separate entities or as part of a library or museum. Film archives may include camera originals (positive and negative), sound recordings, outtakes, scripts, contracts, advertising…
Protein (Cyanobacteria) - PGDBj - Ortholog DB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available ut This Database Database Description Download License Update History of This Database Site Policy | Contact Us Protein (Cyanobacteria) - PGDBj - Ortholog DB | LSDB Archive ... ...List Contact us PGDBj - Ortholog DB Protein (Cyanobacteria) Data detail Data name Protein (Cyanobacteria) DO...switchLanguage; BLAST Search Image Search Home About Archive Update History Data
Reframing transitions and contesting memories: The archive and the archival object in Peruvian cinema

OpenAIRE

Barrow, Sarah

2015-01-01

This essay considers the stories behind the production and screening of two very different Peruvian films that both reveal much about the way the archive, the archival object and archival fragment have worked to disrupt and force a reconsideration of key moments in Peruvian political history of the twentieth century. One, a feature film by Francisco Lombardi, Ojos que no ven/Eyes that don’t see (2003), provides a provocative perspective on the impact of the televisual revelations of the corru...
Hematoxylin and Eosin Counterstaining Protocol for Immunohistochemistry Interpretation and Diagnosis.

Science.gov (United States)

Grosset, Andrée-Anne; Loayza-Vega, Kevin; Adam-Granger, Éloïse; Birlea, Mirela; Gilks, Blake; Nguyen, Bich; Soucy, Geneviève; Tran-Thanh, Danh; Albadine, Roula; Trudel, Dominique

2017-12-21

Hematoxylin and eosin (H&E) staining is a well-established technique in histopathology. However, immunohistochemistry (IHC) interpretation is done exclusively with hematoxylin counterstaining. Our goal was to investigate the potential of H&E as counterstaining (H&E-IHC) to allow for visualization of a marker while confirming the diagnosis on the same slide. The quality of immunostaining and the fast-technical performance were the main criteria to select the final protocol. We stained multiple diagnostic tissues with class I IHC tests with different subcellular localization markers (anti-CK7, CK20, synaptophysin, CD20, HMB45, and Ki-67) and with double-staining on prostate tissues with anti-high molecular weight keratins/p63 (DAB detection) and p504s (alkaline phosphatase detection). To validate the efficacy of the counterstaining, we stained tissue microarrays from the Canadian Immunohistochemistry Quality Control (cIQc) with class II IHC tests (ER, PR, HER2, and p53 markers). Interobserver and intraobserver concordance was assessed by κ statistics. Excellent agreement of H&E-IHC interpretation was observed in comparison with standard IHC from our laboratory (κ, 0.87 to 1.00), and with the cIQc reference values (κ, 0.81 to 1.00). Interobserver and intraobserver agreement was excellent (κ, 0.89 to 1.00 and 0.87 to 1.00, respectively). We therefore show for the first time the potential of using H&E counterstaining for IHC interpretation. We recommend the H&E-IHC protocol to enhance diagnostic precision for the clinical workflow and research studies.
Percutaneous gastrostomy -a report of twenty-seven cases-

International Nuclear Information System (INIS)

Kim, Tae Ho; Lee, Ho Suk; Kim, Yong Joo; Kim, Tae Hun; Suh, Kyung Jin; Kang, Duk Sik

1991-01-01

Nutritional support by gastrostomy feeding is an important treatment adjunct when major swallowing difficulty or debilitating diseases is present. This technique for percutaneous placement of a gastric feeding tube now provides many patients with a simple, safe, and well-tolerated alternative to surgical feeding gastrostomy. We experienced 27 cases of percutaneous gastrostomy from January 1989 to February 1991 at Kyungpook National University Hospital. The underlying diseases of the patients were esophageal cancer (11), pyriform sinus cancer (4), laryngeal cancer (3), tongue cancer (2), lye stricture (1), lung cancer (1), chordoma (1), lethal midline granuloma (1), malignant lymphoma (1), maxillary cancer (1), and tonsil cancer (1). Selding method was used in all cases. In five patients it was difficult to insert the nasogastric tube for air insufflation, and one patient had subtotal gastrectomy with gastrojejunostomy, but gastrostomy was performed in all cases. The general condition improved in all patients. We experienced one case of mild peritonitis, but no other significant complications were observed. Gastrostomy tubes were patient in all patients during their survival period, except two patients who experienced obstruction 2 and 6 months after the procedure. Percutaneous gastrostomy can be used safely and effectively in such patients who have pharyngoesophageal or CNS lesions precluding oral intake
Archives: South African Journal of Botany

African Journals Online (AJOL)

Archives: South African Journal of Botany. Journal Home > Archives: South African Journal of Botany. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. This journal has not ...
License - tRNADB-CE | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us tRNAD...-Share Alike 2.1 Japan. If you use data from this database, please be sure attribute this database as follows: tRNAD...: About This Database Database Description Download License Update History of This Database Site Policy | Contact Us License - tRNADB-CE | LSDB Archive ...
The Wismut biosample archive in the occupational medical research. Pathological and molecular epidemiological archive

International Nuclear Information System (INIS)

Bruening, Thomas; Johnen, Georg

2015-01-01

Worldwide only few biosample archives exist that focus on samples from employees with occupational exposures, especially radiation exposure. The Wismut biosample archive of former uranium miners is a valuable resource for the occupational medical research.
Download - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM... and CAGE TSS aggregation fantom5_new_experimental_details.zip (273 KB) basic (1.3 TB) Simple search and dow...nload 3 (reprocessed)HeliscopeCAGE sequencing, Delve mapping and CAGE TSS aggregation fantom5_rp_exp_details...access [here]. About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Download - FANTOM5 | LSDB Archive ...
Archives: Ethiopian Journal of Health Sciences

African Journals Online (AJOL)

Items 1 - 50 of 65 ... Archives: Ethiopian Journal of Health Sciences. Journal Home > Archives: Ethiopian Journal of Health Sciences. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives ...
Issues and prospects of digitizing liberation movements' archives ...

African Journals Online (AJOL)

User

collective memory. Keywords: digitization,. NAHECS, liberation archives, digitally born, audio- visual. Introduction and background to liberation archives. Archives are generally records of .... long term preservation and access to selected archival materials ..... by International Library of African Music. (ILAM) in. Rhodes.
Life Sciences Data Archive (LSDA)

Data.gov (United States)

National Aeronautics and Space Administration — NASA's Life Sciences Data Archive (LSDA) is an active archive that provides information and data from 1961 (Mercury Project) through current flight and flight analog...
Archives: South African Journal of Education

African Journals Online (AJOL)

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Archives: West African Journal of Medicine

African Journals Online (AJOL)

Items 1 - 40 of 40 ... Archives: West African Journal of Medicine. Journal Home > Archives: West African Journal of Medicine. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 40 of ...
Archives: Journal of Psychology in Africa

African Journals Online (AJOL)

Archives: Journal of Psychology in Africa. Journal Home > Archives: Journal of Psychology in Africa. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 4 of 4 Items. 2005. Vol 15 ...
Providing comprehensive and consistent access to astronomical observatory archive data: the NASA archive model

Science.gov (United States)

McGlynn, Thomas; Fabbiano, Giuseppina; Accomazzi, Alberto; Smale, Alan; White, Richard L.; Donaldson, Thomas; Aloisi, Alessandra; Dower, Theresa; Mazzerella, Joseph M.; Ebert, Rick; Pevunova, Olga; Imel, David; Berriman, Graham B.; Teplitz, Harry I.; Groom, Steve L.; Desai, Vandana R.; Landry, Walter

2016-07-01

Since the turn of the millennium a constant concern of astronomical archives have begun providing data to the public through standardized protocols unifying data from disparate physical sources and wavebands across the electromagnetic spectrum into an astronomical virtual observatory (VO). In October 2014, NASA began support for the NASA Astronomical Virtual Observatories (NAVO) program to coordinate the efforts of NASA astronomy archives in providing data to users through implementation of protocols agreed within the International Virtual Observatory Alliance (IVOA). A major goal of the NAVO collaboration has been to step back from a piecemeal implementation of IVOA standards and define what the appropriate presence for the US and NASA astronomy archives in the VO should be. This includes evaluating what optional capabilities in the standards need to be supported, the specific versions of standards that should be used, and returning feedback to the IVOA, to support modifications as needed. We discuss a standard archive model developed by the NAVO for data archive presence in the virtual observatory built upon a consistent framework of standards defined by the IVOA. Our standard model provides for discovery of resources through the VO registries, access to observation and object data, downloads of image and spectral data and general access to archival datasets. It defines specific protocol versions, minimum capabilities, and all dependencies. The model will evolve as the capabilities of the virtual observatory and needs of the community change.
The new European Hubble archive

Science.gov (United States)

De Marchi, Guido; Arevalo, Maria; Merin, Bruno

2016-01-01

The European Hubble Archive (hereafter eHST), hosted at ESA's European Space Astronomy Centre, has been released for public use in October 2015. The eHST is now fully integrated with the other ESA science archives to ensure long-term preservation of the Hubble data, consisting of more than 1 million observations from 10 different scientific instruments. The public HST data, the Hubble Legacy Archive, and the high-level science data products are now all available to scientists through a single, carefully designed and user friendly web interface. In this talk, I will show how the the eHST can help boost archival research, including how to search on sources in the field of view thanks to precise footprints projected onto the sky, how to obtain enhanced previews of imaging data and interactive spectral plots, and how to directly link observations with already published papers. To maximise the scientific exploitation of Hubble's data, the eHST offers connectivity to virtual observatory tools, easily integrates with the recently released Hubble Source Catalog, and is fully accessible through ESA's archives multi-mission interface.
The Rosetta Science Archive: Status and Plans for Completing and Enhancing the Archive Content

Science.gov (United States)

Heather, D.; Barthelemy, M.; Fraga, D.; Grotheer, E.; O'Rourke, L.; Taylor, M.

2017-09-01

On 30 September 2016, Rosetta's signal flat-lined, confirming that the spacecraft had completed its incredible mission by landing on the surface of Comet 67P/Churyumov-Gerasimenko. Although this marked an end to the spacecraft's active operations, intensive work is still on-going with instrument teams preparing their final science data increments for delivery and ingestion into ESA's Planetary Science Archive (PSA). In addition to this, ESA is establishing contracts with a number of instrument teams to enhance and improve their data and documentation in an effort to provide the best long- term archive possible for the Rosetta mission. This presentation will outline the current status of the Rosetta archive, as well as highlighting some of the 'enhanced archiving' activities planned and underway with the various instrument teams on Rosetta to ensure the scientific legacy of the mission.
Prediction information - GRIPDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us GRI...a.nbdc01665-004 Description of data contents Predicted GPCR interaction regions Data file File name: gripdb_...predicted_info.zip File URL: ftp://ftp.biosciencedbc.jp/archive/gripdb/LATEST/gripdb_predicted_info.zip File... size: 219 KB Simple search URL http://togodb.biosciencedbc.jp/togodb/view/gripdb...entries Data item Description ID Prediction information ID GRIP ID GRIP ID related wigh the prediction Predi

Envirion - KEGG MEDICUS | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available [ Credits ] English ]; } else if ( url.search(//en//) != -1 ) { url = url.replace(/...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us KEGG MEDI...y approved drugs. Data file File name: kegg_medicus_environ_en.zip File URL: ftp:...//ftp.biosciencedbc.jp/archive/kegg-medicus/LATEST/kegg_medicus_environ_en.zip File size: 79 KB Simple searc...h URL http://togodb.biosciencedbc.jp/togodb/view/kegg_medicus_environ_en Data acquisition method - Data anal
Disease - KEGG MEDICUS | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available [ Credits ] English ]; } else if ( url.search(//en//) != -1 ) { url = url.replace(/...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us KEGG MEDI...bling computational processing and analysis of disease data. Data file File name: kegg_medi...cus_disease_en.zip File URL: ftp://ftp.biosciencedbc.jp/archive/kegg-medicus/LATEST/kegg_medicus_d...isease_en.zip File size: 733 KB Simple search URL http://togodb.biosciencedbc.jp/togodb/view/kegg_medicus_di
Drug - KEGG MEDICUS | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available [ Credits ] English ]; } else if ( url.search(//en//) != -1 ) { url = url.replace(/...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us KEGG MEDI...metabolizing enzyme, and other molecular interaction network information. Data file File name: kegg_medi...cus_drug_en.zip File URL: ftp://ftp.biosciencedbc.jp/archive/kegg-medicus/LATEST/kegg_medi...cus_drug_en.zip File size: 5.2 MB Simple search URL http://togodb.biosciencedbc.jp/togodb/view/kegg_medi
License - KEGG MEDICUS | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available [ Credits ] English ]; } else if ( url.search(//en//) != -1 ) { url = url.replace(/...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us KEGG MEDI...ion-NonCommercial-NoDerivs 2.1 Japan. If you use data from this database, please be sure attribute this data...whole of this database, and acquire data; and freely redistribute part or whole of the data from this databa...This Database Site Policy | Contact Us License - KEGG MEDICUS | LSDB Archive ...
Update History of This Database - KAIKOcDNA | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us KAIKOcDNA Update History of This Database Date Update contents 2014/10/20 The URL of the dat... database ( http://sgp.dna.affrc.go.jp/EST/ ) is opened. About This Database Database Description Download License Update Hi...story of This Database Site Policy | Contact Us Update History of This Database - KAIKOcDNA | LSDB Archive ... ...abase maintenance site is changed. 2014/10/08 KAIKOcDNA English archive site is opened. 2004/04/12 KAIKOcDNA
Update History of This Database - TP Atlas | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us TP Atlas Update History of This Database Date Update contents 2013/12/16 The email address i...s ( http://www.tanpaku.org/tpatlas/ ) is opened. About This Database Database Description Download License Update History of Thi...s Database Site Policy | Contact Us Update History of This Database - TP Atlas | LSDB Archive ... ...n the contact information is corrected. 2013/11/19 TP Atlas English archive site is opened. 2008/4/1 TP Atla
Update History of This Database - KEGG MEDICUS | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available glish archive site is opened. 2010/10/01 KEGG MEDICUS ( http://www.kegg.jp/kegg/medicus/ ) is opened. About ...[ Credits ] English ]; } else if ( url.search(//en//) != -1 ) { url = url.replace(/...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us KEGG MEDI...CUS Update History of This Database Date Update contents 2014/05/09 KEGG MEDICUS En...This Database Database Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - KEGG MEDICUS | LSDB Archive ...
Development of Ultra-Super Sensitive Immunohistochemistry and Its Application to the Etiological Study of Adult T-Cell Leukemia/Lymphoma

International Nuclear Information System (INIS)

Hasui, Kazuhisa; Wang, Jia; Tanaka, Yuetsu; Izumo, Shuji; Eizuru, Yoshito; Matsuyama, Takami

2012-01-01

Antigen retrieval (AR) and ultra-super sensitive immunohistochemistry (ultra-IHC) have been established for application to archival human pathology specimens. The original ultra-IHC was the ImmunoMax method or the catalyzed signal amplification system (ImmunoMax/CSA method), comprising the streptavidin-biotin complex (sABC) method and catalyzed reporter deposition (CARD) reaction with visualization of its deposition. By introducing procedures to diminish non-specific staining in the original ultra-IHC method, we developed the modified ImmunoMax/CSA method with AR heating sections in an AR solution (heating-AR). The heating-AR and modified ImmunoMax/CSA method visualized expression of the predominantly simple present form of HTLV-1 proviral DNA pX region p40Tax protein (Tax) in adult T-cell leukemia/lymphoma (ATLL) cells in archival pathology specimens in approximately 75% of cases. The simple present form of Tax detected exhibited a close relation with ATLL cell proliferation. We also established a new simplified CSA (nsCSA) system by replacing the sABC method with the secondary antibody- and horse radish peroxidase-labeled polymer reagent method, introducing the pretreatments blocking non-specific binding of secondary antibody reagent, and diminishing the diffusion of deposition in the CARD reaction. Combined with AR treating sections with proteinase K solution (enzymatic-AR), the nsCSA system visualized granular immunostaining of the complex present form of Tax in a small number of ATLL cells in most cases, presenting the possibility of etiological pathological diagnosis of ATLL and suggesting that the complex present form of Tax-positive ATLL cells were young cells derived from ATLL stem cells. The heating-AR and ultra-IHC detected physiological expression of the p53 protein and its probable phosphorylation by Tax in peripheral blood mononuclear cells of peripheral blood tissue specimens from HTLV-1 carriers, as well as physiological and pathological expression
Archives: Journal of Mining and Geology

African Journals Online (AJOL)

Items 1 - 13 of 13 ... Archives: Journal of Mining and Geology. Journal Home > Archives: Journal of Mining and Geology. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 13 of 13 ...
Archives: African Journal of Oral Health

African Journals Online (AJOL)

Items 1 - 6 of 6 ... Archives: African Journal of Oral Health. Journal Home > Archives: African Journal of Oral Health. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 6 of 6 Items ...
Study on archive management for nuclear facility decommissioning projects

International Nuclear Information System (INIS)

Huang Ling; Gong Jing; Luo Ning; Liao Bing; Zhou Hao

2011-01-01

This paper introduces the main features and status of the archive management for nuclear facility decommissioning projects, and explores and discusses the countermeasures in its archive management. Taking the practice of the archive management system of a reactor decommissioning project as an example, the paper illustrates the establishment of archive management system for the nuclear facility decommissioning projects. The results show that the development of a systematic archive management principle and system for nuclear decommissioning projects and the construction of project archives for the whole process from the design to the decommissioning by digitalized archive management system are one effective route to improve the complete, accurate and systematic archiving of project documents, to promote the standardization and effectiveness of the archive management and to ensure the traceability of the nuclear facility decommissioning projects. (authors)
The FARC fuel archive of WWER

International Nuclear Information System (INIS)

Zizin, M.N.; Parfenova, N.A.; Proselkov, V.N.; Shishkov, L.K.

1998-01-01

The principles of organisation are explained and the structure of the FARC fuel archive for WWER reactors is circumscribed. The objective of archive is accumulation of fuel data, data storage and obtaining of fuel using characteristics. The working version of fuel archive on 01 July 1998 is realised, in which the data tables for fuel assemblies for 169 WWER-440 cycles and 35 WWER-1000 cycles are stored. There are two different versions of fuel archive - for WWER-440 (FARC) and for WWER-1000 (FARC1000). A structure of some tables and the texts of programs for them differ. (Authors)
Capital in the Twenty-First Century

DEFF Research Database (Denmark)

Hansen, Per H.

2014-01-01

Review essay on: Capital in the Twenty-First Century. By Thomas Piketty . Translated by Arthur Goldhammer . Cambridge, Mass.: The Belknap Press of Harvard University Press, 2014. viii + 685 pp......Review essay on: Capital in the Twenty-First Century. By Thomas Piketty . Translated by Arthur Goldhammer . Cambridge, Mass.: The Belknap Press of Harvard University Press, 2014. viii + 685 pp...
Data archiving and analysis for CWDD

International Nuclear Information System (INIS)

Coleman, T.A.; Novick, A.H.; Meystrik, C.C.; Marselle, J.R.

1992-01-01

A computer system has been developed to handle archiving and analysis of data acquired during operations of the Continuous Wave Deuterium Demonstrator (CWDD). Data files generated by the CWDD Instrumentation and Control system are transferred across a local area network to the CWDD Archive system where they are enlisted into the archive and stored on removeable media optical disk drives. A relational database management system maintains an on-line database catalog of all archived files. This database contains information about file contents and formats, and holds signal parameter configuration tables needed to extract and interpret data from the files. Software has been developed to assist the selection and retrieval of data on demand based upon references in the catalog. Data retrieved from the archive is transferred to commercial data visualization applications for viewing, plotting and analysis
COMMUNITY AWARENESS FOR ARCHIVES IN TANZANIA: A ...

African Journals Online (AJOL)

Walter

challenges facing Zanzibar National Archives (ZNA). The study ... legally preserved under the Records and Archives Management Act,. 2002. Lastly, in .... in the findings, the Archives face a lot of challenges on his operation such as lack of ...
A dialogue between archive, knowledge and technology

Directory of Open Access Journals (Sweden)

Henrique Machado dos Santos

2015-11-01

Full Text Available Objective. Perform a brief reflection on knowledge management in archives, emphasizing the connections necessary for a dialogue between archive, knowledge and technology. Method. It consists in review of material previously published in the areas of Management Science, Archival Science and Information Science. The sources consulted consist of books, theses, texts on websites and scientific journal articles indexed in Google Scholar. Thus, the collected data is analyzed qualitatively. Results. There is a close relationship between the archive, knowledge and technology. In this sense, the document has the role of interlocutor in this dialogue. The interdisciplinary scenario envisioned, enhance existing rapprochement between the archival practices and knowledge management, in order to make possible a feedback cycle that will support the practices related to the management, either, of knowledge, of information or of documents. Conclusions. There is need for further studies to address the potential of the archives in order to fill possible gaps theory thus reach multiple looks more points interdisciplinary convergence. Finally, there is the informational potential of archives, then mediated by technology information, can enrich the knowledge management practices, and for this it is essential to strengthen the interdisciplinary relationships between Management Science, Archival Science and Information Science.
Re-using the archive in video posters: a win-win for users and archives

NARCIS (Netherlands)

Sanders, W.; Salgado, Mariana

2017-01-01

Re-use of digital archival content means interpretation; and the ability to create new and original interpretations of cultural heritage materials constitutes necessary contemporary digital and media literacy skills for any (aspiring) scholar and, by extension, informed citizen. For archives, re-use
Protein - Trypanosomes Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us Trypanoso...nhibitor of the protein. Data file File name: trypanosome.zip File URL: ftp://ftp....biosciencedbc.jp/archive/trypanosome/LATEST/trypanosome.zip File size: 1.4 KB Simple search URL http://togo...db.biosciencedbc.jp/togodb/view/trypanosome#en Data acquisition method - Data analysis method - Number of da...ndelian inheritance in Man ) map Location of the gene on a chromosome or its chromosome number pdb PDB ID (P
Download - KEGG MEDICUS | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available [ Credits ] English ]; } else if ( url.search(//en//) != -1 ) { url = url.replace(/...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us KEGG MEDI...search and download 1 README README_e.html - 2 Drug kegg_medicus_drug_en.zip (5.2... MB) Simple search and download 3 Environ kegg_medicus_environ_en.zip (79 KB) Simple search and download 4 Disease kegg_medi...nload License Update History of This Database Site Policy | Contact Us Download - KEGG MEDICUS | LSDB Archive ...
High-Intensity Focused Ultrasound for the Treatment of Wrinkles and Skin Laxity in Seven Different Facial Areas

OpenAIRE

Park, Hyunchul; Kim, Eunjin; Kim, Jeongeun; Ro, Youngsuck; Ko, Jooyeon

2015-01-01

Background High-intensity focused ultrasound (HIFU) treatment has recently emerged in response to the increasing demand for noninvasive procedures for skin lifting and tightening. Objective This study was aimed at evaluating the clinical efficacy of and patient satisfaction with HIFU treatment for wrinkles and laxity in seven different areas of the face in Asian skin. Methods Twenty Korean patients with facial wrinkle and laxity were analyzed after a single session of HIFU treatment. Two inde...

Diagnosis of filamentous fungi on tissue sections by immunohistochemistry using anti-aspergillus antibody.

Science.gov (United States)

Challa, Sundaram; Uppin, Shantveer G; Uppin, Megha S; Pamidimukkala, Umabala; Vemu, Lakshmi

2015-06-01

Identification based on histology alone has limitations as Aspergillus species share morphology with other filamentous fungi. Differentiation of Aspergillus species from hyalohyphomycetes and dematiaceous fungi is important as the antifungal susceptibility varies among different species and genera. Given these problems, ancillary techniques are needed to increase specificity. Our aim was to study the utility of immunohistochemistry (IHC) with anti-Aspergillus antibody in the identification of Aspergillus species and to differentiate them from other filamentous fungi. Fifty formalin fixed, paraffin embedded tissue sections including 47 from cases of culture proven filamentous fungi, 3 from colonies of cultures of hyalohyphomycetes, and 11 smears from cultures were subjected to IHC studies using polyclonal rabbit anti-Aspergillus antibody (Abcam, UK) after antigen retrieval. The IHC on tissue sections was positive in 88% cases involving culture proven Aspergillus species. There was no cross reactivity with Mucorales species, Candida species, dematiaceous fungi and hyalohyphomycetes. Hence immunohistochemistry can be used as an ancillary technique for the diagnosis of Aspergillus species. © The Author 2015. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Engaging With Colonial Archives: Reflections Of An End-User

Directory of Open Access Journals (Sweden)

Ayodeji Olukoju

2016-06-01

Full Text Available Official and/or public archives were a byproduct of colonial rule in Africa. (Archives are a byproduct of administrative governance everywhere. Given the density and diversity of colonial archival records, historians have tended to rely on them for the study of the colonial period. Publications on the use of archives have not captured the perspective of end-users, who often face peculiar challenges in the use of colonial and metropolitan archives. This paper provides an end-user perspective on colonial archives in Nigeria and the United Kingdom. It highlights the challenges of data collection and prospects of optimal use of archival source material. The discussion is of general application to users of colonial archives especially in the former British colonies in Africa.
Update History of This Database - Q-TARO | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us Q-TARO Update History of This Database Date Update contents 2014/10/20 The URL of the portal...ption Download License Update History of This Database Site Policy | Contact Us Update History of This Database - Q-TARO | LSDB Archive ... ... site is changed. 2013/12/17 The URL of the portal site is changed. 2013/12/13 Q-TARO English archive site i...s opened. 2009/11/15 Q-TARO ( http://qtaro.abr.affrc.go.jp/ ) is opened. About This Database Database Descri
ACRF Archive User Meeting Summary

Energy Technology Data Exchange (ETDEWEB)

SA Edgerton; RA McCord; DP Kaiser

2007-10-30

On October 30, 2007, the U.S. Department of Energy’s (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility (ACRF) sponsored an all-day workshop to assess the status of the ACRF Archive. Focus areas included usability of current functions, plans for revised functions, proposals for new functions, and an overarching discussion of new ideas. Although 13 scientists familiar with ACRF and the ARM Program were invited to the workshop, only 10 scientists were available to attend the workshop. ACRF consists of the infrastructure that was developed to support the ARM Program and includes the ACRF Archive (previously called the ARM Archive). The scientists who participated in the meeting ranged from those who used the Archive frequently to those who seldom or never had accessed the Archive. The group was spread across disciplines, i.e. modelers, conservationists, and others from universities and government laboratories. A few of the participants were funded by the ARM Program, but most were not funded currently by ARM. During the past year, several improvements were made to the ACRF Archive to link it with the ARM/ACRF web pages, add a shopping cart feature, and expand on search parameters. Additional modifications have been proposed and prototypes of these proposals were made available for the participants. The participants were given several exercises to do before the meeting, and their feedback was requested to help identify potential problems and shortcomings with the existing structure and to recommend improvements.
Build It—And Advocate for It—And They Will Come: Lessons from a Collaborative Project in Archives Advocacy and Program Development

Directory of Open Access Journals (Sweden)

Jodi Allison-Bunnell

2013-09-01

Full Text Available Libraries at small- and mid-sized academic institutions continue to re-define themselves as journal and monograph collections go online, budgets and staffing remain flat or reduced, and value to student learning and the institutional mission needs to be apparent. This all spells opportunity for archival programs which, with a strong focus on advocacy and daylighting formerly hidden collections of unique content, can re-invigorate the library and spotlight the active role today's service- and user-oriented archives can play in supporting student research, fostering ties with constituents, and ensuring the preservation of an institution's stories and history. A recently-completed National Historical Publications and Records Commission (NHPRC-funded grant project involving seven private institutions in Washington and Oregon utilized a focus on effective advocacy and consulting archivists to move archival programs to the next level. Despite limited resource levels at most of the institutions, tangible and sustainable progress was made on describing collections, establishing best-practices and policies, and perhaps most importantly, cultivating a strong ethic of persistent, creative, low-cost advocacy and outreach.
Science in the archives pasts, presents, futures

CERN Document Server

2017-01-01

"Science in the Archives" reveals affinities and continuities among the sciences of the archives, across many disciplines and centuries, in order to present a better picture of essential archival practices and, thereby, the meaning of science. For in both the natural and human sciences, archives of the most diverse forms make cumulative, collective knowledge possible. Yet in contrast to laboratories, observatories, or the field, archives have yet to be studied across the board as central sites of science. The volume covers episodes in the history of astronomy, geology, genetics, classical philology, climatology, history, medicine, and ancient natural philosophy, as well as fundamental practices such as collecting, retrieval strategies, and data mining. The time frame spans doxology in Greco-Roman antiquity to NSA surveillance techniques and the quantified-self movement. Each chapter explores the practices, politics, economics, and open-ended potential of the sciences of the archives, making this the first boo...
Care of architectural archival material

Directory of Open Access Journals (Sweden)

Perović-Ivović Svetlana

2015-01-01

Full Text Available The paper focuses on the complex issue of the preservation and maintenance of architectural records as a distinctive type of archival material, addressing the problems of care and storage of diverse oversize documents done on different supports: architectural drawings on drafting cloth, waxed cloth, paper, plastic film; reproductions such as blueprints, diazo prints, and other types of non-textual documents. Attention is paid to all types of damage caused both by internal factors, i.e. resulting from the nature of the support material, and by external factors involved in the degradation of architectural archival material. The paper also presents comparative conservation methods applied to architectural documents kept in the Archives of Yugoslavia. In conclusion, it points to the importance of preventive care as regards storage conditions, handling and display of this type of archival material.
Building an Archival Collections Portal

Directory of Open Access Journals (Sweden)

Stuart Marquis

2008-06-01

Full Text Available Columbia University Libraries has developed the Archival Collections Portal, a unified search system helping users discover archival resources in a streamlined way. We combined the power of Lucene and Solr to search XML, parse JSON objects, create EAD-compliant documents, and deliver results in an easy-to-use interface. By reusing MARC records and employing new search engine features and techniques, we are able to bring important and hard-to-find collections to researchers and archivists. The canonical home page of the Portal is http://www.columbia.edu/library/archival/.
Experiment information - GRIPDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us GRI...a.nbdc01665-002 Description of data contents Experimentally identified GPCR interaction regions Data file File name: gri...pdb_exp_info.zip File URL: ftp://ftp.biosciencedbc.jp/archive/gripdb/LATEST/gripdb_exp_info.zip ...File size: 6.2 KB Simple search URL http://togodb.biosciencedbc.jp/togodb/view/gri...es Data item Description ID Experiment information ID GRIP ID1 GRIP ID related wigh the experiment GRIP ID2 No. in GRI
Digital audiovisual archives

CERN Document Server

Stockinger, Peter

2013-01-01

Today, huge quantities of digital audiovisual resources are already available - everywhere and at any time - through Web portals, online archives and libraries, and video blogs. One central question with respect to this huge amount of audiovisual data is how they can be used in specific (social, pedagogical, etc.) contexts and what are their potential interest for target groups (communities, professionals, students, researchers, etc.).This book examines the question of the (creative) exploitation of digital audiovisual archives from a theoretical, methodological, technical and practical
Methodological Challenges in Protein Microarray and Immunohistochemistry for the Discovery of Novel Autoantibodies in Paediatric Acute Disseminated Encephalomyelitis

Science.gov (United States)

Peschl, Patrick; Ramberger, Melanie; Höftberger, Romana; Jöhrer, Karin; Baumann, Matthias; Rostásy, Kevin; Reindl, Markus

2017-01-01

Acute disseminated encephalomyelitis (ADEM) is a rare autoimmune-mediated demyelinating disease affecting mainly children and young adults. Differentiation to multiple sclerosis is not always possible, due to overlapping clinical symptoms and recurrent and multiphasic forms. Until now, immunoglobulins reactive to myelin oligodendrocyte glycoprotein (MOG antibodies) have been found in a subset of patients with ADEM. However, there are still patients lacking autoantibodies, necessitating the identification of new autoantibodies as biomarkers in those patients. Therefore, we aimed to identify novel autoantibody targets in ADEM patients. Sixteen ADEM patients (11 seronegative, 5 seropositive for MOG antibodies) were analysed for potential new biomarkers, using a protein microarray and immunohistochemistry on rat brain tissue to identify antibodies against intracellular and surface neuronal and glial antigens. Nine candidate antigens were identified in the protein microarray analysis in at least two patients per group. Immunohistochemistry on rat brain tissue did not reveal new target antigens. Although no new autoantibody targets could be found here, future studies should aim to identify new biomarkers for therapeutic and prognostic purposes. The microarray analysis and immunohistochemistry methods used here have several limitations, which should be considered in future searches for biomarkers. PMID:28327523
The Manifesto or the ten commandments of creating a private archive

Directory of Open Access Journals (Sweden)

Waldemar Chorążyczewski

2013-03-01

Full Text Available If, pursuant to the spirit of our time, and the interest of all the users of the archives, the versatility of the domain of archive studies, has the greatest value, then our goal is not to accumulate the archives of private provenance by the public or social data archives, but rather, to strive for the private archives in Poland to come about again. The public archives have natural right to exclusivity as far as amassing public archival materials is concerned. However, apart from that, parity of the right to cumulate materials ought to be upheld. Private archives ought to have the right to gather materials of other private archivists, as well as social data archives. The owners of such private archives, should also have the right to appoint an inheriting subject from among the public or private archives. Parity of archives will contribute towards an upswing in the position of the public archives as an institution of public trust. The public archives will keep a registry of private and social data archives. The latter will not be conveyed to anyone without the knowledge of the public archives. Public archives will also be required to take possession of the private and social data archive materials, in the event of their being closed down.
Results of de-novo and Motif activity analyses - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM... JASPAR) Data file File name: Motifs File URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/phase1.3...tabase Database Description Download License Update History of This Database Site Policy | Contact Us Results of de-novo and Motif activity analyses - FANTOM5 | LSDB Archive ...
Self-archiving to Institutional Repositories Is Improved by Assisted and Mandated Deposit; Disciplinary Culture is not a Factor. A Review of: Xia, Jingfeng. “Assessment of Self-Archiving in Institutional Repositories: Across Disciplines.” The Journal of Academic Librarianship 33.6 (Dec. 2007: 647-54.

Directory of Open Access Journals (Sweden)

Gaby Haddow

2008-06-01

Full Text Available Objective – To test the assumption that authors familiar with subject-based repositories are more likely to self-archive to institutional repositories. Design – Comparative content analysis. Setting – Institutional repositories (IRs from the following seven universities: Queensland University of Technology (QUT, University of Melbourne, University of Queensland, Lund University, University of Glasgow, University of Southampton, and University of Strathclyde. The IRs included in the study were selected on the basis of repository size and use of EPrints software. Faculty size data and IR deposit policies were drawn from universities’ Websites. Methods – Each IR was searched to determine the number of deposits in the disciplines of chemistry, physics, economics and sociology. Physics and economics were selected because these disciplines have established internationally renowned subject-based repositories, in contrast to chemistry and sociology, which have not. Deposits from the disciplines were identified from subject terms, keywords and departmental names in metadata records. A “deposit rate” for the four disciplines in each IR was calculated. The metadata records were examined for name of the depositor, date of deposit, full-text availability, item type, and format. Information in the field “Deposited By” was used to identify the extent of self-archiving (that is, deposited by the author. Faculty size for the four disciplines at the seven universities was established from departmental Web site information. For the purposes of making comparisons between the IRs, these data were converted into “rates of faculty” size by dividing the number of faculty in the department by the total number of faculty at the institution. A weighted rate of deposits by discipline was calculated by dividing the rate offaculty size by the deposit rates. To take into account disciplinary differences in publication productivity, these rates were
36 CFR 1253.1 - National Archives Building.

Science.gov (United States)

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false National Archives Building... PUBLIC AVAILABILITY AND USE LOCATION OF RECORDS AND HOURS OF USE § 1253.1 National Archives Building. (a) The National Archives Building is located at 700 Pennsylvania Avenue, NW., Washington, DC 20408...
Building a successful archival programme a practical approach

CERN Document Server

Ramos, Marisol

2006-01-01

This valuable resource provides information on best practices and solutions to successfully establish an archival programme; it uses a practical approach, without the use of technical or theoretical jargon. Additionally it serves as a companion text in a theoretical archival course. The book provides easy-to-follow advice on how to assess the information needs of any institution and the greater community for which the archives were created to serve. Guidelines for achievable goals are provided for starting an archives programme in an environment where a small budget or even a 'no budget' can threaten the future of the archives. First book that attempts to de-mystify archives Practical approaches without the use of technical jargon Easy to follow Plans of Action.
A single simple procedure for dewaxing, hydration and heat-induced epitope retrieval (HIER) for immunohistochemistry in formalin fixed paraffin-embedded tissue

DEFF Research Database (Denmark)

Paulsen, I M S; Dimke, H; Frische, S

2015-01-01

Heat-induced epitope retrieval (HIER) is widely used for immunohistochemistry on formalin fixed paraffin-embedded tissue and includes temperatures well above the melting point of paraffin. We therefore tested whether traditional xylene-based removal of paraffin is required on sections from paraff...... of dewaxing in xylene. In conclusion, the HIER procedure described and tested can be used as a single procedure enabling dewaxing, hydration and epitope retrieval for immunohistochemistry in formalin fixed paraffin-embedded tissue....
Email-Set Visualization: Facilitating Re-Finding in Email Archives

OpenAIRE

Gorton, Douglas; Murthy, Uma; Vemuri, Naga Srinivas; Pérez-Quiñones, Manuel A.

2007-01-01

In this paper we describe ESVT – EmailSet Visualization Tool, an email archive tool that provides users a visualization to re-find and discover information in their email archive. ESVT is an end-to-end email archive tool that can be used from archiving a user’s email messages to visualizing queries on the email archive. We address email archiving by allowing import of email messages from an email server or from a standard existing email client. The central idea in ESVT’s visualization, an “em...
Locating Archives within the Landscape: Records, Memory and Place

Directory of Open Access Journals (Sweden)

Jeannette Bastian

2014-12-01

Full Text Available Linking archives, memory and landscape, this article considers a series of questions, and attempts to address some of them: How do archivists and scholars who concern themselves with archives think about place and its relationship to records? Why and how is place archival? How are those archival relationships expressed and what do they signify for the people inhabiting that space? What are the memory implications of the relationship between place, archives and community and how are traditional archives both the products of place as well as influencers themselves upon the landscape?
Picture archiving and communication in radiology.

Science.gov (United States)

Napoli, Marzia; Nanni, Marinella; Cimarra, Stefania; Crisafulli, Letizia; Campioni, Paolo; Marano, Pasquale

2003-01-01

After over 80 years of exclusive archiving of radiologic films, at present, in Radiology, digital archiving is increasingly gaining ground. Digital archiving allows a considerable reduction in costs and space saving, but most importantly, immediate or remote consultation of all examinations and reports in the hospital clinical wards, is feasible. The RIS system, in this case, is the starting point of the process of electronic archiving which however is the task of PACS. The latter can be used as radiologic archive in accordance with the law provided that it is in conformance with some specifications as the use of optical long-term storage media or with electronic track of change. PACS archives, in a hierarchical system, all digital images produced by each diagnostic imaging modality. Images and patient data can be retrieved and used for consultation or remote consultation by the reporting radiologist who requires images and reports of previous radiologic examinations or by the referring physician of the ward. Modern PACS owing to the WEB server allow remote access to extremely simplified images and data however ensuring the due regulations and access protections. Since the PACS enables a simpler data communication within the hospital, security and patient privacy should be protected. A secure and reliable PACS should be able to minimize the risk of accidental data destruction, and should prevent non authorized access to the archive with adequate security measures in relation to the acquired knowledge and based on the technological advances. Archiving of data produced by modern digital imaging is a problem now present also in small Radiology services. The technology is able to readily solve problems which were extremely complex up to some years ago as the connection between equipment and archiving system owing also to the universalization of the DICOM 3.0 standard. The evolution of communication networks and the use of standard protocols as TCP/IP can minimize

Archival storage solutions for PACS

Science.gov (United States)

Chunn, Timothy

1997-05-01

While they are many, one of the inhibitors to the wide spread diffusion of PACS systems has been robust, cost effective digital archive storage solutions. Moreover, an automated Nearline solution is key to a central, sharable data repository, enabling many applications such as PACS, telemedicine and teleradiology, and information warehousing and data mining for research such as patient outcome analysis. Selecting the right solution depends on a number of factors: capacity requirements, write and retrieval performance requirements, scaleability in capacity and performance, configuration architecture and flexibility, subsystem availability and reliability, security requirements, system cost, achievable benefits and cost savings, investment protection, strategic fit and more.This paper addresses many of these issues. It compares and positions optical disk and magnetic tape technologies, which are the predominant archive mediums today. Price and performance comparisons will be made at different archive capacities, plus the effect of file size on storage system throughput will be analyzed. The concept of automated migration of images from high performance, high cost storage devices to high capacity, low cost storage devices will be introduced as a viable way to minimize overall storage costs for an archive. The concept of access density will also be introduced and applied to the selection of the most cost effective archive solution.
The FAA's postmortem forensic toxicology self-evaluated proficiency test program: the second seven years.

Science.gov (United States)

Chaturvedi, Arvind K; Craft, Kristi J; Cardona, Patrick S; Rogers, Paul B; Canfield, Dennis V

2009-05-01

During toxicological evaluations of samples from fatally injured pilots involved in civil aviation accidents, a high degree of quality control/quality assurance (QC/QA) is maintained. Under this philosophy, the Federal Aviation Administration (FAA) started a forensic toxicology proficiency-testing (PT) program in July 1991. In continuation of the first seven years of the PT findings reported earlier, PT findings of the next seven years are summarized herein. Twenty-eight survey samples (12 urine, 9 blood, and 7 tissue homogenate) with/without alcohols/volatiles, drugs, and/or putrefactive amine(s) were submitted to an average of 31 laboratories, of which an average of 25 participants returned their results. Analytes in survey samples were correctly identified and quantitated by a large number of participants, but some false positives of concern were reported. It is anticipated that the FAA's PT program will continue to serve the forensic toxicology community through this important part of the QC/QA for laboratory accreditations.
Colorectal Carcinomas With Isolated Loss of PMS2 Staining by Immunohistochemistry.

Science.gov (United States)

Alpert, Lindsay; Pai, Reetesh K; Srivastava, Amitabh; McKinnon, Wendy; Wilcox, Rebecca; Yantiss, Rhonda K; Arcega, Ramir; Wang, Hanlin L; Robert, Marie E; Liu, Xiuli; Pai, Rish K; Zhao, Lei; Westerhoff, Maria; Hampel, Heather; Kupfer, Sonia; Setia, Namrata; Xiao, Shu-Yuan; Hart, John; Frankel, Wendy L

2018-04-01

- Isolated loss of PMS2 staining is an uncommon immunophenotype in colorectal carcinomas, accounting for approximately 4% of tumors with microsatellite instability. Limited information regarding these tumors is available in the literature. - To compare the clinicopathologic features of colorectal carcinomas with isolated PMS2 loss by immunohistochemistry to those with other forms of mismatch repair deficiency. - Ninety-three colorectal carcinomas with isolated PMS2 loss by immunohistochemistry and 193 with other forms of mismatch repair deficiency were identified. Forty (43%) of the isolated PMS2 loss cases and 35 control cases (18%) had a known germline mutation or a clinical diagnosis of Lynch syndrome. - Overall, isolated PMS2-loss tumors occurred in significantly younger patients ( P PMS2-loss group also exhibited increased odds of disease-specific death (odds ratio [OR], 3.09; 95% CI, 1.41-6.85; P = .007). When the analysis was restricted to germline mutation/Lynch syndrome cases and controls, no significant differences were detected for age, sex, tumor location, tumor grade, histologic features, or distant metastases, although a trend toward increased odds of disease-specific death in the isolated PMS2-loss group was evident (OR, 3.87; 95% CI, 0.89-27.04; P = .10). - Unusual clinicopathologic features observed in colorectal carcinomas with isolated PMS2 loss are likely related to the high proportion of cases caused by germline mutations. Isolated PMS2-loss tumors may demonstrate more aggressive behavior than other tumors with microsatellite instability, but larger studies are needed to investigate that possibility further.
American archives and climate change: Risks and adaptation

Directory of Open Access Journals (Sweden)

T. Mazurczyk

Full Text Available Climate change directly affects the future security of cultural resources. Cultural heritage and in particular, archives, are increasingly at risk of degradation due to climate change threats and triggers. This study evaluated present and future consequences of water-related climate change impacts using a mapping methodology to assess exposure of American archives to incompatible weather extremes. Susceptibility to climate change threats like sea level rise, storm surge, surface water flooding, and humidity, all influenced by a combination of temperature rise and increased precipitation, at a worst-case scenario were assessed for 1232 archival repositories. Results indicate that approximately 98.8% of archives are likely to be affected by at least one climate risk factor, though on average, most archives are at low risk of exposure (90% when risk factors are combined. Future storm surge plus sea level rise was likely to impact 17.7% of archival repositories with 22.1% affected by only storm surge and 4.3% affected by only sea level rise (1.8-m scenario. Fewer archives were likely to be susceptible to surface water flooding (2.4%. More than 90% of archives were estimated to have a temperature change greater than ±1 °C, with 7.5% of sites likely to change by ±10 °C, and 69.5% of archives were likely to receive at least 152 mm more rainfall by 2100 over current annual averages. In terms of sustainability, developing appropriate socio-economic planning schemes that integrate cumulative exposure of archives to future climate patterns is critically important for safeguarding society and its heritage. The outcomes from the risk assessment in this study aid in the decision-making process by promoting strategic adaptation protocols and providing administrators a way to prioritize archival management goals based on the expected severity of future climate change impacts. Keywords: Archives, Climate change, Sea level rise, Storm surge, Cultural
Nuclear-like Seq in mt Genome - RMG | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available ar-like Seq in mt Genome Data detail Data name Nuclear-like Seq in mt Genome DOI 10...e Site Policy | Contact Us Nuclear-like Seq in mt Genome - RMG | LSDB Archive ... ...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us RMG Nucle
Cluster (Viridiplantae) - PGDBj - Ortholog DB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available 0”. This cluster ID is uniquely-assigned by the PGDBj Ortholog Database. Cluster size Number of proteins aff...r About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Cluster (Viridiplantae) - PGDBj - Ortholog DB | LSDB Archive ... ...List Contact us PGDBj - Ortholog DB Cluster (Viridiplantae) Data detail Data name Cluster (Viridiplantae) DO...switchLanguage; BLAST Search Image Search Home About Archive Update History Data
Cluster (Cyanobacteria) - PGDBj - Ortholog DB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available 3090”. This cluster ID is uniquely-assigned by the PGDBj Ortholog Database. Cluster size Number of proteins ...ster About This Database Database Description Download License Update History of This Database Site Policy | Contact Us Cluster (Cyanobacteria) - PGDBj - Ortholog DB | LSDB Archive ... ...List Contact us PGDBj - Ortholog DB Cluster (Cyanobacteria) Data detail Data name Cluster (Cyanobacteria) DO...switchLanguage; BLAST Search Image Search Home About Archive Update History Data
Effect of Enrofloxacin on Histochemistry, Immunohistochemistry and Molecular Changes in Lamb Articular Cartilage.

Science.gov (United States)

Khazaeel, Kaveh; Mazaheri, Yazdan; Hashemi Tabar, Mahmood; Najafzadeh, Hossein; Morovvati, Hassan; Ghadrdan, Alireza

2015-01-01

Enrofloxacin is a synthetic chemotherapeutic agent from the class of the fluoroquinolones that is widely used to treat bacterial infections. It is metabolized to ciprofloxacin in the body as active metabolite. Fluoroquinolones change in the articular cartilage, especially with high doses and more than two weeks use. So, due to relatively excessive use of enrofloxacin in mammals and similarity of lambs to human subjects with respect to skeletal activity cycles, this study was done to investigate the effects of enrofloxacin on some cellular and molecular changes in growing lamb articular cartilage to evaluate some possible mechanisms involved these changes. Twelve, 2-month-old male lambs divided into three groups: control group received only normal saline; therapeutic group received 5mg/kg enrofloxacin subcutaneously, daily, for 15 days and toxic group received 35 mg/kg enrofloxacin in the same manner as therapeutic group. Twenty four hours after the last dose, the animals were sacrificed, and their stifle joints were dissected. Sampling from distal femoral and proximal tibial extremities was done quickly for further histological and molecular studies. Collagen-п content was studied with avidin-biotin immunohistochemistry method in different groups. Expression of Sox9 and caspase-3 was evaluated by Real-time PCR. Immunohistochemical changes were included decreases of matrix proteoglycans, carbohydrates, and Collagen-п in the toxic group. Some of these changes were observed in the therapeutic group with less intensity in comparison to the toxic group. Enrofloxacin were significantly decreased (P≤0.05). Sox9 expression in therapeutic and toxic groups compared to control group. But caspase -3 expressions in the toxic group significantly increased (P≤0.0001) with a comparison to other groups, while, between control and therapeutic groups, there were no significant differences. So, it can be concluded that enrofloxacin increases apoptosis in chondrocytes and
Database Dump - fRNAdb | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us fRNAdb Database Dump Data detail Data name Database Dump DOI 10.18908/lsdba.nbdc00452-002 De... data (tab separeted text) Data file File name: Database_Dump File URL: ftp://ftp....biosciencedbc.jp/archive/frnadb/LATEST/Database_Dump File size: 673 MB Simple search URL - Data acquisition...s. Data analysis method - Number of data entries 4 files - About This Database Database Description Download... License Update History of This Database Site Policy | Contact Us Database Dump - fRNAdb | LSDB Archive ...
Archives: Tropical Journal of Pharmaceutical Research

African Journals Online (AJOL)

Items 1 - 50 of 97 ... Archives: Tropical Journal of Pharmaceutical Research. Journal Home > Archives: Tropical Journal of Pharmaceutical Research. Log in or Register to get access to full text downloads.
Archives: Nigerian Journal of Physiological Sciences

African Journals Online (AJOL)

Items 1 - 19 of 19 ... Archives: Nigerian Journal of Physiological Sciences. Journal Home > Archives: Nigerian Journal of Physiological Sciences. Log in or Register to get access to full text downloads.
Archives: Nigerian Journal of Pharmaceutical Research

African Journals Online (AJOL)

Items 1 - 9 of 9 ... Archives: Nigerian Journal of Pharmaceutical Research. Journal Home > Archives: Nigerian Journal of Pharmaceutical Research. Log in or Register to get access to full text downloads.
(reprocessed)HeliscopeCAGE sequencing, Delve mapping and CAGE TSS aggregation - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...ntified by CAGE tag analysis (BED format) *.rdna.fa.gz: rDNA sequences (FASTA format) Data file File name: fantom...5_rp_exp_details.zip File URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/20161221/fantom5_rp_exp_detai...tp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/reprocessed/hg38_latest/basic/ File size: 1.4 TB File na...me: (reprocessed)basic (Mus musculus) File URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/datafiles/reproce
EPICS data archiver at SSRF beamlines

International Nuclear Information System (INIS)

Hu Zheng; Mi Qingru; Zheng Lifang; Li Zhong

2014-01-01

The control system of SSRF (Shanghai Synchrotron Radiation Facility) is based on EPICS (Experimental Physics and Industrial Control System). Operation data storage for synchrotron radiation facility is important for its status monitoring and analysis. At SSRF, operation data used to be index files recorded by traditional EPICS Channel Archiver. Nevertheless, index files are not suitable for long-term maintenance and difficult for data analysis. Now, RDB Channel Archiver and MySQL are used for SSRF beamline operation data archiving, so as to promote the data storage reliability and usability. By applying a new uploading mechanism to RDB Channel Archiver, its writing performance is improved. A web-based GUI (Graphics User Interface) is also developed to make it easier to access database. (authors)
Old and New Archives

Directory of Open Access Journals (Sweden)

Ioana Vasiloiu

2015-01-01

Full Text Available Library and museum archives are real testimony of collective memory. Old or new, their "universe" is fascinating. They are the path to an almost forgotten world with all its cultural and intellectual problems or allow us to reconsider the social, historical, political and cultural present. The inestimable value of their manuscripts, books and periodicals made medieval Romanian library archives to be famous in that age. Its content figured out the Romanian humanist's vast intellectual activity and their connection to European values. Their remains, which can be found today especially at Romanian Academy Library, depict some aspects of Romanian medieval cultural life. Particularly, with its huge number of manuscripts, books and periodicals, the National Romanian Literature Museum archives contribute to Romanian history reconstruction from the commencement to present.
Archival claims in Southern Africa | Mnjama | Innovation

African Journals Online (AJOL)

The author examines the problem of archival claims in the region. He begins by defining the broad categories of archives that fall under the rubric of `migrated archives' and shows that virtually all states in the region are affected by problems related to this phenomenon. He argues that failure to distinguish the different ...
Un cinéma palestinien « en mal d’archive » The “Archive Fever” of Palestinian Cinema

Directory of Open Access Journals (Sweden)

Laure Fourest

2012-05-01

Full Text Available À partir de l’analyse de trois films palestiniens réalisés dans les années 2000, cet article propose d’interroger l’insertion d’images d’archives par les cinéastes dans leur montage : quelles stratégies mettent-ils en œuvre et à quelles fins ? Qu’apportent des images d’archives en plus des témoignages filmés ? Comment le recours à ces images permet-il de participer au débat historiographique qui sous-tend et détermine en partie le conflit israélo-palestinien ? Dans le contexte palestinien où il n’existe pas d’institution archivistique officielle, les archives sont porteuses d’enjeux particulièrement saillants, donnant lieu à un véritable « mal d’archive ». Celui-ci fait naître une multiplicité de stratégies cinématographiques visant à questionner cette zone d’inconfort, où le maniement des qualités émotionnelles et sensorielles de l’archive peut être un moyen de faire preuve.Through the analysis of three Palestinian films created in the 2000-2010 period, this article considers filmmakers’ insertion of archival images in their montages: what strategies do they employ and for what purpose? What do archival images add to filmed testimony? How does the use of these images enable participation in the historiographical debate underlying and partly determining the Israel-Palestine conflict? In the Palestinian context, where no official archive institution exists, archives entail particularly salient issues, making their lack truly sore. This generates a multiplicity of cinematographic strategies aiming to challenge this discomfort zone, where the manipulation of the emotional and sensorial qualities of archives can be a means of proving something.
Update History of This Database - PSCDB | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us PSCDB Update History of This Database Date Update contents 2016/11/30 PSCDB English archive ...site is opened. 2011/11/13 PSCDB ( http://idp1.force.cs.is.nagoya-u.ac.jp/pscdb/ ) is opened. About This Database Database... Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - PSCDB | LSDB Archive ...
Distribution of dendritic cells expressing dendritic cell-specific ICAM-3-grabbing non-integrin (DC-SIGN, CD209): Morphological analysis using a novel Photoshop-aided multiple immunohistochemistry technique.

Science.gov (United States)

Masuda, Akihiro; Nishikawa, Toshio

2014-08-01

The distribution of dendritic cells (DCs) expressing DC-specific ICAM-3-grabbing non-integrin (DC-SIGN, CD209) and the morphological interaction of DC-SIGN⁺ DCs with other cells, especially B cells, in tonsillar and other lymphoid tissues were investigated by multiple immunohistochemistry (IHC) using the graphics editing program Photoshop, which enabled staining with 4 or more antibodies in formalin-fixed paraffin sections. Images obtained by repetition of conventional IHC using diaminobenzidine color development in a tissue section were processed on Photoshop for multiple staining. DC-SIGN⁺ DCs were present in the area around the lymphoid follicles and formed a DC-SIGN⁺ DC-rich area, and these cells contacted not only T cells, fascin⁺ DCs, and blood vessels but also several subsets of B cells simultaneously, including naïve and memory B cells. DC-SIGN⁺ DCs may play an important role in the regulation of the immune response mediated by not only T cells but also B cells. The multiple IHC method introduced in the present study is a simple and useful method for analyzing details of complex structures. Because this method can be applied to routinely processed paraffin sections with conventional IHC with diaminobenzidine, it can be applied to a wide variety of archival specimens.
Data archiving system implementation in ITER's CODAC Core System

International Nuclear Information System (INIS)

Castro, R.; Abadie, L.; Makushok, Y.; Ruiz, M.; Sanz, D.; Vega, J.; Faig, J.; Román-Pérez, G.; Simrock, S.; Makijarvi, P.

2015-01-01

Highlights: • Implementation of ITER's data archiving solution. • Integration of the solution into CODAC Core System. • Data archiving structure. • High efficient data transmission into fast plant system controllers. • Fast control and data acquisition in Linux. - Abstract: The aim of this work is to present the implementation of data archiving in ITER's CODAC Core System software. This first approach provides a client side API and server side software allowing the creation of a simplified version of ITERDB data archiving software, and implements all required elements to complete data archiving flow from data acquisition until its persistent storage technology. The client side includes all necessary components that run on devices that acquire or produce data, distributing and streaming to configure remote archiving servers. The server side comprises an archiving service that stores into HDF5 files all received data. The archiving solution aims at storing data coming for the data acquisition system, the conventional control and also processed/simulated data.

Space power technology for the twenty-first century (SPT21)

International Nuclear Information System (INIS)

Borger, W.U.; Massie, L.D.

1988-01-01

During the spring and summer months of 1987, the Aero Propulsion Laboratory of the Air Force Wright Aeronautical Laboratories, Wright-Patterson AFB, Ohio in cooperation with the Air Force Space Technology Center at Kirtland AFB, New Mexico, undertook an initiative to develop a Strategic Plan for Space Power Technology Development. The initiative was called SPT21, Space Power Technology for the Twenty-First Century. The planning process involved the participation of other Government organizations (U.S. Army, Navy, DOE and NASA) along with major aerospace companies and universities. Following an SPT21 kickoff meeting on 28 May 1987, detailed strategic planning was accomplished through seven (7) Space Power Technology Discipline Workshops commencing in June 1987 and concluding in August 1987. Technology Discipline Workshops were conducted in the following areas: (1) Solar Thermal Dynamic Power Systems (2) Solar Photovoltaic Cells and Arrays (3) Thermal Management Technology (4) Energy Storage Technology (5) Nuclear Power Systems Technology (6) Power Conditioning, Distribution and Control and (7) Systems Technology/Advanced Concepts. This technical paper summarizes the planning process and describes the salient findings and conclusions of the workshops
Cellular Proliferation by Multiplex Immunohistochemistry Identifies High-Risk Multiple Myeloma in Newly Diagnosed, Treatment-Naive Patients.

Science.gov (United States)

Ely, Scott; Forsberg, Peter; Ouansafi, Ihsane; Rossi, Adriana; Modin, Alvin; Pearse, Roger; Pekle, Karen; Perry, Arthur; Coleman, Morton; Jayabalan, David; Di Liberto, Maurizio; Chen-Kiang, Selina; Niesvizky, Ruben; Mark, Tomer M

2017-12-01

Therapeutic options for multiple myeloma (MM) are growing, yet clinical outcomes remain heterogeneous. Cytogenetic analysis and disease staging are mainstays of risk stratification, but data suggest a complex interplay between numerous abnormalities. Myeloma cell proliferation is a metric shown to predict outcomes, but available methods are not feasible in clinical practice. Multiplex immunohistochemistry (mIHC), using multiple immunostains simultaneously, is universally available for clinical use. We tested mIHC as a method to calculate a plasma cell proliferation index (PCPI). By mIHC, marrow trephine core biopsy samples were costained for CD138, a plasma cell-specific marker, and Ki-67. Myeloma cells (CD138 + ) were counted as proliferating if coexpressing Ki-67. Retrospective analysis was performed on 151 newly diagnosed, treatment-naive patients divided into 2 groups on the basis of myeloma cell proliferation: low (PCPI ≤ 5%, n = 87), and high (PCPI > 5%, n = 64). Median overall survival (OS) was not reached versus 78.9 months (P = .0434) for the low versus high PCPI groups. Multivariate analysis showed that only high-risk cytogenetics (hazard ratio [HR] = 2.02; P = .023), International Staging System (ISS) stage > I (HR = 2.30; P = .014), and PCPI > 5% (HR = 1.70; P = .041) had independent effects on OS. Twenty-three (36%) of the 64 patients with low-risk disease (ISS stage 1, without high-risk cytogenetics) were uniquely reidentified as high risk by PCPI. PCPI is a practical method that predicts OS in newly diagnosed myeloma and facilitates broader use of MM cell proliferation for risk stratification. Copyright © 2017 Elsevier Inc. All rights reserved.
Art from Archives: The Archival Trend in Contemporary Art and Culture

Directory of Open Access Journals (Sweden)

Martyn Jolly

2014-12-01

Full Text Available If the archival mode has been important over the last thirty years, it will only continue to become more important in the next thirty years. In the fifteen years since Lev Manovich wrote The Language of New Media, in which he identified the database with its operations of searching navigating and viewing as the new-media correlate to the novel and cinema with their operations of narrative storytelling, databases have only increased in scale, complexity and ubiquity — at an exponential rate, as is the case with all technologies. Archives are being uncovered or created at an unprecedented rate, digitized at an unprecedented rate and made searchable at an unprecedented rate. New ways of interrogating the archive, new ways of searching metadata and new ways of presenting iterations from the archive, such as more complex data visualizations, are being developed. At the same time photographs are manifesting themselves in a wider range of material substances — etched in stone or glass, printed on cloth or metal, projected on walls and buildings, and sliding along LED arrays or screens. But the story isn’t all about the seductions of new media. The more artists and historians work in this area, the more they realize that there are still troves and troves of objects and images, laid down in all their recalcitrant materiality by those who came before, just waiting to be rediscovered and reinvented.
Profiles of international archives: Les archives Jean Piaget, University of Geneva, Switzerland.

Science.gov (United States)

Burman, Jeremy Trevelyan

2013-05-01

This research report provides a look behind closed doors at the Jean Piaget Archives in Geneva, Switzerland. It situates the potential visitor, contextualizes the Archives in its own history, and then describes what scholars can expect to find. New details about Piaget's views on Equal Rights and Equal Pay are also provided, including a look at how they affected the women who worked his factory (esp. Bärbel Inhelder). (PsycINFO Database Record (c) 2013 APA, all rights reserved).
THE LA PALMA DATA ARCHIVE

NARCIS (Netherlands)

ZUIDERWIJK, EJ; MARTIN, R; RAIMOND, E; VANDIEPEN, GNJ

The operation of the La Palma Data Archive is described in detail. The archive contains data taken since early 1986 with the Isaac Newton Group; 74% of the 260,000 entries are of astronomical sources. Several hundreds of queries are made on the catalog each year, resulting in approximately one
36 CFR 1280.66 - May I use the National Archives Library?

Science.gov (United States)

2010-07-01

... Archives Library? 1280.66 Section 1280.66 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... the Washington, DC, Area? § 1280.66 May I use the National Archives Library? The National Archives Library facilities in the National Archives Building and in the National Archives at College Park are...
Tango archiving service status

International Nuclear Information System (INIS)

Abeille, G.; Pierre-Joseph, S.; Guyot, J.; Ounsy, M.; Rubio, S.; Strangolino, G.; Passuello, R.

2012-01-01

In modern scientific instruments like ALBA, ELLETRA or Synchrotron Soleil, the monitoring and tuning of thousands of parameters is essential to drive high-performing accelerators and beamlines. To keep track of these parameters and to easily manage large volumes of technical data, an archiving service is a key component of a modern control system like Tango. To achieve this, a high-available archiving service is provided as a feature of the Tango control system. This archiving service stores data coming from the Tango control system into MySQL or Oracle databases. Tree sub-services are provided: 1) An historical service with an archiving period up to 10 seconds; 2) A short term service providing a few weeks retention with a period up to 100 milliseconds; and 3) A snapshot service which takes 'snapshots' of Tango parameters and can reapply them to the control system on user demand. This paper presents how to obtain a high-performance and scalable service based on our feedback after several years of operation. The deployment architecture in the different Tango institutes will then be detailed. The paper concludes with a description of the next steps and incoming features which will be available in the next future. (authors)
NASA Data Archive Evaluation

Science.gov (United States)

Holley, Daniel C.; Haight, Kyle G.; Lindstrom, Ted

1997-01-01

The purpose of this study was to expose a range of naive individuals to the NASA Data Archive and to obtain feedback from them, with the goal of learning how useful people with varied backgrounds would find the Archive for research and other purposes. We processed 36 subjects in four experimental categories, designated in this report as C+R+, C+R-, C-R+ and C-R-, for computer experienced researchers, computer experienced non-researchers, non-computer experienced researchers, and non-computer experienced non-researchers, respectively. This report includes an assessment of general patterns of subject responses to the various aspects of the NASA Data Archive. Some of the aspects examined were interface-oriented, addressing such issues as whether the subject was able to locate information, figure out how to perform desired information retrieval tasks, etc. Other aspects were content-related. In doing these assessments, answers given to different questions were sometimes combined. This practice reflects the tendency of the subjects to provide answers expressing their experiences across question boundaries. Patterns of response are cross-examined by subject category in order to bring out deeper understandings of why subjects reacted the way they did to the archive. After the general assessment, there will be a more extensive summary of the replies received from the test subjects.
Donors and archives a guidebook for successful programs

CERN Document Server

Purcell, Aaron D

2015-01-01

Donors and Archives: A Guidebook for Successful Programs highlights the importance of development and fundraising for archives, while focusing on the donor and potential donor. Their interest, their support, their enthusiasm, and their stuff are vital to the success of archival programs.
Discussion the exploitation of nuclear power archival resources

International Nuclear Information System (INIS)

Fan Fei

2012-01-01

In recent years with the development of government policy on nuclear power by the 'proper development' to 'positive rapid development', the nuclear power stations have mushroomed. As an important part of nuclear power plant the archives plays an important role in ensuring the safe and stable operation. With the increasing nuclear power archival resources, its how the rational and efficient development and utilization of nuclear power as an important corporate archivists subject. Nuclear power archives is no longer a static file 'archive' but a steady steam of out knowledge and wisdom of the 'think tank', 'treasure', our archives staff also no longer simply a medium used to provide lending, but to provide reference 'experts' and 'think tank'. Based on the analysis of nuclear features of archival resources, the use of a new perspective on nuclear power development and utilization of enterprise file made bold attempts and innovation. (author)
Research Groups & Research Subjects - RED | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available rch Groups & Research Subjects Data detail Data name Research Groups & Research Sub... Number of data entries 174 entries Data item Description Research ID Research ID (Subject number) Institute...tion Download License Update History of This Database Site Policy | Contact Us Research Groups & Research Subjects - RED | LSDB Archive ... ...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us RED Resea... Organization Section Section (Department) User name User name Experimental title Experimental title (Rese
NASA's Long-Term Astrophysics Data Archives

OpenAIRE

Rebull, L. M.; Desai, V.; Teplitz, H.; Groom, S.; Akeson, R.; Berriman, G. B.; Helou, G.; Imel, D.; Mazzarella, J. M.; Accomazzi, A.; McGlynn, T.; Smale, A.; White, R.

2017-01-01

NASA regards data handling and archiving as an integral part of space missions, and has a strong track record of serving astrophysics data to the public, beginning with the the IRAS satellite in 1983. Archives enable a major science return on the significant investment required to develop a space mission. In fact, the presence and accessibility of an archive can more than double the number of papers resulting from the data. In order for the community to be able to use the data, they have to b...
Archival Discipline in Dewey Decimal Classification

Directory of Open Access Journals (Sweden)

Laura Manzoni

2017-05-01

Full Text Available This paper regards the ways archival discipline is treated in DDC. After a short introduction about the discipline in Italy, the essay focuses on the analysis of division 020 of DDC 23, with specific attention to section 025 and with punctual reference to section 651, concerning archival material. The aim of the paper is to point out archival discipline’s peculiarities and its differences from library science, as well as underlining the critical issues on how this discipline is handled in DDC.
Life Sciences Data Archive (LSDA)

Science.gov (United States)

Fitts, M.; Johnson-Throop, Kathy; Thomas, D.; Shackelford, K.

2008-01-01

In the early days of spaceflight, space life sciences data were been collected and stored in numerous databases, formats, media-types and geographical locations. While serving the needs of individual research teams, these data were largely unknown/unavailable to the scientific community at large. As a result, the Space Act of 1958 and the Science Data Management Policy mandated that research data collected by the National Aeronautics and Space Administration be made available to the science community at large. The Biomedical Informatics and Health Care Systems Branch of the Space Life Sciences Directorate at JSC and the Data Archive Project at ARC, with funding from the Human Research Program through the Exploration Medical Capability Element, are fulfilling these requirements through the systematic population of the Life Sciences Data Archive. This program constitutes a formal system for the acquisition, archival and distribution of data for Life Sciences-sponsored experiments and investigations. The general goal of the archive is to acquire, preserve, and distribute these data using a variety of media which are accessible and responsive to inquiries from the science communities.
Studio Constructing an Archive - Modelkabinettet

DEFF Research Database (Denmark)

2012-01-01

. This has, among other subjects, included an analysis of the architectural exhibition "OMA Progress" at the Barbican Arts Centre in London as well as OMA's architecture, design strategy and media usage. The study has been based on discussions of archives, collections and architecture exhibitions as cultural...... products, historiography, media and architectural representation. Based on the above studies, the students have developed their own projects, which reflect in a critical manner on exhibitions, archives and collections. In Studio Constructing an Archive we focus on architectural representation and its...... significance and influence on the development of architecture and our understanding of architecture. During the spring semester, we have, in particular, been discussing the model and its media characteristics....
Archival services and technologies for scientific data

International Nuclear Information System (INIS)

Meyer, Jörg; Hardt, Marcus; Streit, Achim; Wezel, Jos van

2014-01-01

After analysis and publication, there is no need to keep experimental data online on spinning disks. For reliability and costs inactive data is moved to tape and put into a data archive. The data archive must provide reliable access for at least ten years following a recommendation of the German Science Foundation (DFG), but many scientific communities wish to keep data available much longer. Data archival is on the one hand purely a bit preservation activity in order to ensure the bits read are the same as those written years before. On the other hand enough information must be archived to be able to use and interpret the content of the data. The latter is depending on many also community specific factors and remains an areas of much debate among archival specialists. The paper describes the current practice of archival and bit preservation in use for different science communities at KIT for which a combination of organizational services and technical tools are required. The special monitoring to detect tape related errors, the software infrastructure in use as well as the service certification are discussed. Plans and developments at KIT also in the context of the Large Scale Data Management and Analysis (LSDMA) project are presented. The technical advantages of the T10 SCSI Stream Commands (SSC-4) and the Linear Tape File System (LTFS) will have a profound impact on future long term archival of large data sets.
Archival Services and Technologies for Scientific Data

Science.gov (United States)

Meyer, Jörg; Hardt, Marcus; Streit, Achim; van Wezel, Jos

2014-06-01

After analysis and publication, there is no need to keep experimental data online on spinning disks. For reliability and costs inactive data is moved to tape and put into a data archive. The data archive must provide reliable access for at least ten years following a recommendation of the German Science Foundation (DFG), but many scientific communities wish to keep data available much longer. Data archival is on the one hand purely a bit preservation activity in order to ensure the bits read are the same as those written years before. On the other hand enough information must be archived to be able to use and interpret the content of the data. The latter is depending on many also community specific factors and remains an areas of much debate among archival specialists. The paper describes the current practice of archival and bit preservation in use for different science communities at KIT for which a combination of organizational services and technical tools are required. The special monitoring to detect tape related errors, the software infrastructure in use as well as the service certification are discussed. Plans and developments at KIT also in the context of the Large Scale Data Management and Analysis (LSDMA) project are presented. The technical advantages of the T10 SCSI Stream Commands (SSC-4) and the Linear Tape File System (LTFS) will have a profound impact on future long term archival of large data sets.
Archives and societal provenance Australian essays

CERN Document Server

Piggott, Michael

2012-01-01

Records and archival arrangements in Australia are globally relevant because Australia's indigenous people represent the oldest living culture in the world, and because modern Australia is an ex-colonial society now heavily multicultural in outlook. Archives and Societal Provenance explores this distinctiveness using the theoretical concept of societal provenance as propounded by Canadian archival scholars led by Dr Tom Nesmith. The book's seventeen essays blend new writing and re-workings of earlier work, comprising the fi rst text to apply a societal provenance perspective to a national sett
Evaluation of epidermal growth factor receptor (EGFR) by chromogenic in situ hybridization (CISH) and immunohistochemistry (IHC) in archival gliomas using bright-field microscopy.

Science.gov (United States)

Marquez, Abbey; Wu, Rina; Zhao, Jianxin; Tao, Jianhua; Shi, Zuorong

2004-03-01

Overexpression of EGFR secondary to EGFR gene amplification is a common feature in primary malignant gliomas. To correctly assess EGFR protein and gene level as possible prognostic and predictive markers in gliomas, straightforward assays, which can be used routinely in the pathology laboratory to evaluate EGFR status, becomes critical. EGFR gene amplification and chromosome 7 aneuploidy was detected in 34 formalin-fixed, paraffin-embedded benign and malignant gliomas by chromogenic in situ hybridization (CISH) using digoxigenin-labeled EGFR and biotin-labeled chromosome 7 centromeric probes. The results were evaluated by bright-field microscopy under a 40x objective lens. EGFR protein level was detected by immunohistochemistry (IHC) using monoclonal antibody 31G7. Five cases, 3 astrocytoma grade III (33%) and 2 glioblastoma multiforme (GBM) (33%), had EGFR amplification displayed as diaminobenzidine-stained multiple dots suggesting the pattern of double-minute chromosomes. Chromosome 7 polysomy was found in 68% gliomas, 100% GBM, 67% astrocytoma grade III, 42% astrocytoma grade II, 50% astrocytoma grade I, 100% ependymoma, and the 1 case of mixed glioma III. High expression of EGFR protein was present in 62% gliomas and displayed membrane and cytoplasmic staining. All tumors with EGFR gene amplification showed EGFR high expression. High expression of EGFR without gene amplification was observed in all grades of gliomas. Simultaneous detection of EGFR gene copies or chromosome 7 centromere signals along with tissue morphology allows us to compare CISH results easily with IHC results. Our results show that CISH is an objective, practical, and accurate assay to screen for EGFR gene status in gliomas.
Infrastructural challenges on archives and recordkeeping at the ...

African Journals Online (AJOL)

... immediate attention. Given the importance of the national memory in the form of archives or records, the paper recommends that records and archival infrastructural issues be given due attention by both the government and the National Archives of Zimbabwe itself in order to ensure sound records management practices.

Iterating archival footage and the memory of war

NARCIS (Netherlands)

Noordegraaf, J.; Bordina, A.; Campanini, S.; Mariani, A.

2012-01-01

In this article I focus on the archive as a specific site of memory, in particular the audiovisual archive. I investigate the use of audiovisual archival records as sources for remembering war, specifically the war in the former Yugoslavia (1991-1995). I do so by discussing one particular case
A comprehensive cost model for NASA data archiving

Science.gov (United States)

Green, J. L.; Klenk, K. F.; Treinish, L. A.

1990-01-01

A simple archive cost model has been developed to help predict NASA's archiving costs. The model covers data management activities from the beginning of the mission through launch, acquisition, and support of retrospective users by the long-term archive; it is capable of determining the life cycle costs for archived data depending on how the data need to be managed to meet user requirements. The model, which currently contains 48 equations with a menu-driven user interface, is available for use on an IBM PC or AT.
EAC Working Group for Archaeological Archives, A European View of Selecting for Archaeological Archives

Directory of Open Access Journals (Sweden)

Brown, Duncan H.

2017-12-01

Full Text Available This paper examines the issues around selecting for archaeological archives, including the reasons for doing so, how selection fit into a project and the methodological framework. The context is ‘Making Choices’, a project of the Europae Archaeologiae Consilium that is looking at how all choices are made across archaeological practice, while the foundations are provided by existing standards for archiving and for selection.
A new archival infrastructure for highly-structured astronomical data

Science.gov (United States)

Dovgan, Erik; Knapic, Cristina; Sponza, Massimo; Smareglia, Riccardo

2018-03-01

With the advent of the 2020 Radio Astronomy Telescopes era, the amount and format of the radioastronomical data is becoming a massive and performance-critical challenge. Such an evolution of data models and data formats require new data archiving techniques that allow massive and fast storage of data that are at the same time also efficiently processed. A useful expertise for efficient archiviation has been obtained through data archiving of Medicina and Noto Radio Telescopes. The presented archival infrastructure named the Radio Archive stores and handles various formats, such as FITS, MBFITS, and VLBI's XML, which includes description and ancillary files. The modeling and architecture of the archive fulfill all the requirements of both data persistence and easy data discovery and exploitation. The presented archive already complies with the Virtual Observatory directives, therefore future service implementations will also be VO compliant. This article presents the Radio Archive services and tools, from the data acquisition to the end-user data utilization.
Finding "Science" in the Archives of the Spanish Monarchy.

Science.gov (United States)

Portuondo, Maria M

2016-03-01

This essay explores the history of several archives that house the early modern records of Spanish imperial science. The modern "archival turn" urges us to think critically about archives and to recognize in the history of these collections an embedded, often implicit, history that--unless properly recognized, acknowledged, and understood--can distort the histories we are trying to tell. This essay uses a curious episode in the history of science to illustrate how Spanish archives relate to each other and shape the collections they house. During the late eighteenth century a young navy officer, Martín Fernández de Navarrete, was dispatched to all the principal archives of the Spanish monarchy with a peculiar mission: he was to search for evidence that the Spanish in fact had a scientific tradition. This essay uses his mission to explain how the original purpose of an archive--the archive's telos--may persist as a strong and potentially deterministic force in the work of historians of science. In the case of the archives discussed, this telos was shaped by issues as wide ranging as defending a nation's reputation against claims of colonial neglect and as idiosyncratic as an archivist's selection criteria.
Exploiting NASA's Cumulus Earth Science Cloud Archive with Services and Computation

Science.gov (United States)

Pilone, D.; Quinn, P.; Jazayeri, A.; Schuler, I.; Plofchan, P.; Baynes, K.; Ramachandran, R.

2017-12-01

NASA's Earth Observing System Data and Information System (EOSDIS) houses nearly 30PBs of critical Earth Science data and with upcoming missions is expected to balloon to between 200PBs-300PBs over the next seven years. In addition to the massive increase in data collected, researchers and application developers want more and faster access - enabling complex visualizations, long time-series analysis, and cross dataset research without needing to copy and manage massive amounts of data locally. NASA has started prototyping with commercial cloud providers to make this data available in elastic cloud compute environments, allowing application developers direct access to the massive EOSDIS holdings. In this talk we'll explain the principles behind the archive architecture and share our experience of dealing with large amounts of data with serverless architectures including AWS Lambda, the Elastic Container Service (ECS) for long running jobs, and why we dropped thousands of lines of code for AWS Step Functions. We'll discuss best practices and patterns for accessing and using data available in a shared object store (S3) and leveraging events and message passing for sophisticated and highly scalable processing and analysis workflows. Finally we'll share capabilities NASA and cloud services are making available on the archives to enable massively scalable analysis and computation in a variety of formats and tools.
Oral History Archives | Fellowship | Indian Academy of Sciences

Indian Academy of Sciences (India)

Oral history archive. Audio and video documentaries. In the Academy Council meeting held in December 2011, the proposal of creating an 'Oral history archive' was discussed and finalized for implementation. The archive is intended to be a repository of audio and video documentaries of some of the leading scientists of ...
Update History of This Database - RED | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us RED Update History of This Database Date Update contents 2015/12/21 Rice Expression Database English archi...s Database Database Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - RED | LSDB Archive ... ...ve site is opened. 2000/10/1 Rice Expression Database ( http://red.dna.affrc.go.jp/RED/ ) is opened. About Thi
No innocent deposits forming archives by rethinking appraisal

CERN Document Server

Cox, Richard J

2003-01-01

The public increase of interest in the past has not necessarily brought with it a greater understanding about how archives are formed. To this end, Richard Cox takes a serious look at archival repositories and collections. Cox suggests that archives do not just happen, but are consciously shaped (and sometimes distorted) by archivists, the creators of records, and other individuals and institutions. In this series of essays, Cox offers archivists rare insight into the fundamentals of appraisal, and historians and other users of archives the opportunity to appreciate the collections they all to
PACS: Picture Archiving and Communication Systems

International Nuclear Information System (INIS)

Gell, G.; Schneider, G.H.; Becker, M.; Wiltgen, M.

1988-01-01

A growing number of medical imaging modalities produces images that are initially calculated and stored as digital information in a computer. For diagnosis, archiving and communication a hardcopy (usually on X-ray film) is produced from these data. It is estimated that in 1995 about 80% of all imaging procedures will generate digital images. This trend leads to the development of systems, where the X-ray film is not only replaced in his function as a radiation detector, but also in his other functions as the medium for image presentation, image communication and image archiving. In short, one wants a completely digital picture archiving and communication system (PACS). The rationale behind PACS efforts is to achieve better functionality and to save costs, mainly by reducing the consumption of expensive X-ray films and the need for storage space for film archives. 7 refs., 2 figs. (Author)
Database Description - tRNADB-CE | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us tRNAD...B-CE Database Description General information of database Database name tRNADB-CE Alter...CC BY-SA Detail Background and funding Name: MEXT Integrated Database Project Reference(s) Article title: tRNAD... 2009 Jan;37(Database issue):D163-8. External Links: Article title: tRNADB-CE 2011: tRNA gene database curat...n Download License Update History of This Database Site Policy | Contact Us Database Description - tRNADB-CE | LSDB Archive ...
YAC contig information - RGP physicalmap | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available 8908/lsdba.nbdc00318-06-001 Description of data contents YAC contigs on the rice chromosomes Data file File name: rgp_physical...map_yac_contigs.zip File URL: ftp://ftp.biosciencedbc.jp/archive/rgp-physicalmap/LATEST/rgp_physical...sciencedbc.jp/togodb/view/rgp_physicalmap_yac_contigs#en Data acquisition method The range including YAC con...m Description Chrom. No. Chromosome number Region Region number Physical map image The file name of rice physical...n Download License Update History of This Database Site Policy | Contact Us YAC contig information - RGP physicalmap | LSDB Archive ...
High Energy Astrophysics Science Archive Research Center

Data.gov (United States)

National Aeronautics and Space Administration — The High Energy Astrophysics Science Archive Research Center (HEASARC) is the primary archive for NASA missions dealing with extremely energetic phenomena, from...
CAGE peaks identified as true TSS by TSS classifier - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...p://ftp.biosciencedbc.jp/archive/fantom5/datafiles/phase1.3/extra/TSS_classifier/ File size: 32 MB Simple se...arch URL - Data acquisition method - Data analysis method TSS Classifier（ http://sourceforge.net/p/tom...ase Description Download License Update History of This Database Site Policy | Contact Us CAGE peaks identified as true TSS by TSS classifier - FANTOM5 | LSDB Archive ...
Archival approaches in the work of Paul Otlet

Directory of Open Access Journals (Sweden)

Leomar José Montilla Peña

2015-02-01

Full Text Available We present a bibliometric study of the Treaty of Documentation of Paul Otlet where the goal was to analyze approaches the archival area registered on it. For this study, used the descriptive words method and the associated words method. We applied a longitudinal statistical sampling for periods 1898 to 1933, because he published the first three scientists manuals the classical Archives. The results revealed that there is a total of 10 references related to the archives, the author being Otlet else mentioned, it has more citations and references on this area. The topics most frequently used by Otlet on archival science for discursive reasoning were: methods of organization and administrative documents. The analysis finds that archival approaches registered in the Treaty of Documentation have centrality and low density.
Evolution of Archival Storage (from Tape to Memory)

Science.gov (United States)

Ramapriyan, Hampapuram K.

2015-01-01

Over the last three decades, there has been a significant evolution in storage technologies supporting archival of remote sensing data. This section provides a brief survey of how these technologies have evolved. Three main technologies are considered - tape, hard disk and solid state disk. Their historical evolution is traced, summarizing how reductions in cost have helped being able to store larger volumes of data on faster media. The cost per GB of media is only one of the considerations in determining the best approach to archival storage. Active archives generally require faster response to user requests for data than permanent archives. The archive costs have to consider facilities and other capital costs, operations costs, software licenses, utilities costs, etc. For meeting requirements in any organization, typically a mix of technologies is needed.
National Archives and Records Administration Employee Locator

Data.gov (United States)

National Archives and Records Administration — The National Archives and Records Administration Employee Locator is an online system that provides the name, office symbol, location, room, telephone number, and...
Data Mining the Internet Archive Collection

Directory of Open Access Journals (Sweden)

Caleb McDaniel

2014-03-01

Full Text Available The collections of the Internet Archive (IA include many digitized sources of interest to historians, including early JSTOR journal content, John Adams’s personal library, and the Haiti collection at the John Carter Brown Library. In short, to quote Programming Historian Ian Milligan, “The Internet Archive rocks.” In this lesson, you’ll learn how to download files from such collections using a Python module specifically designed for the Internet Archive. You will also learn how to use another Python module designed for parsing MARC XML records, a widely used standard for formatting bibliographic metadata.
Making Nuclear Malaysia Email Archives Portable

International Nuclear Information System (INIS)

Shaharum Ramli

2013-01-01

Nuclear Malaysia e-mails can be accessed from any computer and anywhere, even worldwide, via web access. However, this mobility is lost when the e-mails are moved to a personal computer into archive files such as Microsoft Outlook data files. Outlook e-mail archives can only be read on the computer where it is stored. This removal has to be done because of storage space constraints on the e-mail server. This paper shows how e-mail archives can be made portable, brought and read anywhere using a free portable e-mail client application such as Mozilla Thunderbird, Portable Edition. (author)
Real-time data archiving for GTA

International Nuclear Information System (INIS)

Cole, R.A.; Atkins, W.H.

1992-01-01

The architecture of the GTA (Ground Test Accelerator) control system, the nature of a typical GTA commissioning activity, and the varied interests of those analyzing the data make it challenging to develop a general-purpose scheme for archiving data and making the data available to those who will use it. Addressing the needs of those who develop and trouble-shoot hardware and software increases the challenge. This paper describes the aspects of GTA that affect archiving operations and discusses how the features of the EPICS archiving module meet a variety of needs for storing and accessing data. (Author) 2 refs

Sparking ideas, making connections:Digital Film Archives and collaborative scholarship

OpenAIRE

Atkinson, Sarah Anne

2012-01-01

Film archiving is a rapidly changing field as a result of the accelerating development of online digital technologies. Taking as its case study the example of SP-ARK (1), the Sally Potter online film archive, this article proposes a notable shift from the traditional single-user archive model to emerging multi-user, collaborative forms of archival scholarship. The digital preservation and presentation of archival materials dramatically impact upon the nature of the types and levels of access ...
Update History of This Database - RPD | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us RPD Update History of This Database Date Update contents 2016/02/02 Rice Proteome Database English archi...s Database Database Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - RPD | LSDB Archive ... ...ve site is opened. 2003/01/07 Rice Proteome Database ( http://gene64.dna.affrc.go.jp/RPD/ ) is opened. About Thi
Update History of This Database - PLACE | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us PLACE Update History of This Database Date Update contents 2016/08/22 The contact address is...s Database Database Description Download License Update History of Thi...s Database Site Policy | Contact Us Update History of This Database - PLACE | LSDB Archive ... ... changed. 2014/10/20 The URLs of the database maintenance site and the portal site are changed. 2014/07/17 PLACE English archi
Molecular Morphology of Pituitary Cells, from Conventional Immunohistochemistry to Fluorescein Imaging

Directory of Open Access Journals (Sweden)

R. Yoshiyuki Osamura

2011-04-01

Full Text Available In situ hybridization (ISH at the electron microscopic (EM level is essential for elucidating the intracellular distribution and role of mRNA in protein synthesis. EM-ISH is considered to be an important tool for clarifying the intracellular localization of mRNA and the exact site of pituitary hormone synthesis on the rough endoplasmic reticulum. A combined ISH and immunohistochemistry (IHC under EM (EM-ISH&IHC approach has sufficient ultrastructural resolution, and provides two-dimensional images of the subcellular localization of pituitary hormone and its mRNA in a pituitary cell. The advantages of semiconductor nanocrystals (quantum dots, Qdots and confocal laser scanning microscopy (CLSM enable us to obtain three-dimensional images of the subcellular localization of pituitary hormone and its mRNA. Both EM-ISH&IHC and ISH & IHC using Qdots and CLSM are useful for understanding the relationships between protein and mRNA simultaneously in two or three dimensions. CLSM observation of rab3B and SNARE proteins such as SNAP-25 and syntaxin has revealed that both rab3B and SNARE system proteins play important roles and work together as the exocytotic machinery in anterior pituitary cells. Another important issue is the intracellular transport and secretion of pituitary hormone. We have developed an experimental pituitary cell line, GH3 cell, which has growth hormone (GH linked to enhanced yellow fluorescein protein (EYFP. This stable GH3 cell secretes GH linked to EYFP upon stimulation by Ca2+ influx or Ca2+ release from storage. This GH3 cell line is useful for the real-time visualization of the intracellular transport and secretion of GH. These three methods from conventional immunohistochemistry and fluorescein imaging allow us to consecutively visualize the process of transcription, translation, transport and secretion of anterior pituitary hormone.
Medical image digital archive: a comparison of storage technologies

Science.gov (United States)

Chunn, Timothy; Hutchings, Matt

1998-07-01

A cost effective, high capacity digital archive system is one of the remaining key factors that will enable a radiology department to eliminate film as an archive medium. The ever increasing amount of digital image data is creating the need for huge archive systems that can reliably store and retrieve millions of images and hold from a few terabytes of data to possibly hundreds of terabytes. Selecting the right archive solution depends on a number of factors: capacity requirements, write and retrieval performance requirements, scaleability in capacity and performance, conformance to open standards, archive availability and reliability, security, cost, achievable benefits and cost savings, investment protection, and more. This paper addresses many of these issues. It compares and positions optical disk and magnetic tape technologies, which are the predominant archive mediums today. New technologies will be discussed, such as DVD and high performance tape. Price and performance comparisons will be made at different archive capacities, plus the effect of file size on random and pre-fetch retrieval time will be analyzed. The concept of automated migration of images from high performance, RAID disk storage devices to high capacity, NearlineR storage devices will be introduced as a viable way to minimize overall storage costs for an archive.
Archives: HTS Teologiese Studies / Theological Studies

African Journals Online (AJOL)

Items 1 - 50 of 120 ... Archives: HTS Teologiese Studies / Theological Studies. Journal Home > Archives: HTS Teologiese Studies / Theological Studies. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search ...
Vendor neutral archive in PACS

International Nuclear Information System (INIS)

Agarwal, Tapesh Kumar; Sanjeev

2012-01-01

An archive is a location containing a collection of records, documents, or other materials of historical importance. An integral part of Picture Archiving and Communication System (PACS) is archiving. When a hospital needs to migrate a PACS vendor, the complete earlier data need to be migrated in the format of the newly procured PACS. It is both time and money consuming. To address this issue, the new concept of vendor neutral archive (VNA) has emerged. A VNA simply decouples the PACS and workstations at the archival layer. This is achieved by developing an application engine that receives, integrates, and transmits the data using the different syntax of a Digital Imaging and Communication in Medicine (DICOM) format. Transferring the data belonging to the old PACS to a new one is performed by a process called migration of data. In VNA, a number of different data migration techniques are available to facilitate transfer from the old PACS to the new one, the choice depending on the speed of migration and the importance of data. The techniques include simple DICOM migration, prefetch-based DICOM migration, medium migration, and the expensive non-DICOM migration. “Vendor neutral” may not be a suitable term, and “architecture neutral,” “PACS neutral,” “content neutral,” or “third-party neutral” are probably better and preferred terms. Notwithstanding this, the VNA acronym has come to stay in both the medical IT user terminology and in vendor nomenclature, and radiologists need to be aware of its impact in PACS across the globe
Archives: Nigerian Journal of Gastroenterology and Hepatology

African Journals Online (AJOL)

Items 1 - 15 of 15 ... Archives: Nigerian Journal of Gastroenterology and Hepatology. Journal Home > Archives: Nigerian Journal of Gastroenterology and Hepatology. Log in or Register to get access to full text downloads.
Archives: Journal of Medical and Biomedical Sciences

African Journals Online (AJOL)

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Archives: Egyptian Journal of Medical Human Genetics

African Journals Online (AJOL)

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Archives: South African Journal of Clinical Nutrition

African Journals Online (AJOL)

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Archives: Journal of Medicine and Biomedical Research

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Archives: African Journal of Finance and Management

African Journals Online (AJOL)

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Archives: Arab Journal of Nephrology and Transplantation

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Archives: African Journal of Science and Technology

African Journals Online (AJOL)

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Archives: Journal of Science and Technology (Ghana)

African Journals Online (AJOL)

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ModelArchiver—A program for facilitating the creation of groundwater model archives

Science.gov (United States)

Winston, Richard B.

2018-03-01

ModelArchiver is a program designed to facilitate the creation of groundwater model archives that meet the requirements of the U.S. Geological Survey (USGS) policy (Office of Groundwater Technical Memorandum 2016.02, https://water.usgs.gov/admin/memo/GW/gw2016.02.pdf, https://water.usgs.gov/ogw/policy/gw-model/). ModelArchiver version 1.0 leads the user step-by-step through the process of creating a USGS groundwater model archive. The user specifies the contents of each of the subdirectories within the archive and provides descriptions of the archive contents. Descriptions of some files can be specified automatically using file extensions. Descriptions also can be specified individually. Those descriptions are added to a readme.txt file provided by the user. ModelArchiver moves the content of the archive to the archive folder and compresses some folders into .zip files.As part of the archive, the modeler must create a metadata file describing the archive. The program has a built-in metadata editor and provides links to websites that can aid in creation of the metadata. The built-in metadata editor is also available as a stand-alone program named FgdcMetaEditor version 1.0, which also is described in this report. ModelArchiver updates the metadata file provided by the user with descriptions of the files in the archive. An optional archive list file generated automatically by ModelMuse can streamline the creation of archives by identifying input files, output files, model programs, and ancillary files for inclusion in the archive.
Archives decontamination by gamma irradiation

International Nuclear Information System (INIS)

Bratu, E.; Moise, I.V.; Cutrubinis, M.; Negut, D.C.; Virgolici, Marian

2009-01-01

The treatment of archives with gamma irradiation is an efficient and environmental friendly alternative for biological decontamination of large volume of archives. It substitutes the use of chemicals for conservation and contributes to safer workplaces. This work is targeting documents from recent archives where the value of information is not obsolete and may become an important historical and cultural testimony. For a successful treatment, an optimal absorbed dose has to be established. An excessive dose may damage papers and an insufficient one will not reduce bioburden to the desired level. An interdisciplinary team was performing various physical and chemical tests in order to evaluate deterioration of paper at high doses. In the case of natural disaster, it is not excluded the '' emergency '' treatment for documents in immediate danger of total destruction. (authors)
The MWA archive infrastructure: archiving terabytes of data over dedicated WAN connections

Science.gov (United States)

Wicenec, Andreas; Pallot, Dave; Checcucci, Alessio; Kitaeff, Slava; Vinsen, Kevin; Wu, Chen

2012-09-01

The Murchison Wide Field Array (MWA) is being upgraded from 32 tiles to 128 tiles of 16 dual-polarization dipole antennas. In the course of this project the software and the data infrastructure are also undergoing a major overhaul in order to cope with a more continuous and remote operational model; and the substantial increase in data rate (400 MB/s from the correlator plus 160 MB/s from the real time imaging pipeline). During the course of 2012/13 the data collected by the MWA will be transported via a dedicated 40 Gbit WAN network link between the Murchison Radio Observatory (MRO) and Perth (700 km). However, this network will not be available for some time; and until then, the data will be transported using disk arrays instead. Once in Perth, the data will be ingested into a tape library. The archiving process itself consists of various steps executed either at the MRO site or in Perth, and makes use of a modied version of the archiving system from the Atacama Large Millimeter Array (ALMA). This includes the extraction of meta-data from the original raw data and the ingestion and generation of the appropriate data links for the MWA archive. The MWA correlator generates a collection of small les all belonging to the same observation. In order to optimise the network transfer and the storage of those les they are transparently packed into larger containers at the MRO site and subsequently handled as one big le. This paper describes the setup of the MWA archiving infrastructure.
The clinical characteristics of twenty-eight idiopathic pulmonary fibrosis cases

International Nuclear Information System (INIS)

Yu Yong; Shi Minhua; Hu Huacheng

2007-01-01

Objective: To summarize the clinical characteristics of idiopathic pulmonary fibrosis (IPF). Methods: The clinical characteristics of twenty-eight cases diagnosed as IPF between 1991 and 2006 were studied retrospectively. Results: Most IPF patients had an insidious onset of progressive dyspnea and non-productive cough. Inspiratory crackles and finger clubbing were also noted in most patients. The most impressive appearance of their radiography was peripheral reticular and nodular opacities, distributed largely at the lung bases. Pulmonary function test showed restrictive impairment and impaired oxygen diffusion. The arterial blood gas analysis revealed type I respiratory failure. One IPF case was complicated with lung cancer. The symptoms of fifteen cases(71.4%) were relieved under the therapy with glucocorticoid. Seven patients died as yet in our group and the middle duration was 24 months. Conclusions: The diagnosis of IPF relies mostly on the clinical characteristics, radiography, pulmonary function test, blood gas analysis and exclusion of other ILD. Atypical cases need lung biopsy to do further the diagnosis. Therapy with glucocorticoid may be effective in some cases. Prognosis in IPF cases complicated with lung cancer is poor. (authors)

Monoclonal antibodies against pregnancy-specific β1-glycoprotein (SP1) in immunohistochemistry and radioimmunoassay

International Nuclear Information System (INIS)

Wahlstroem, T.; Heikinheimo, M.

1983-01-01

Monoclonal mouse antibodies against pregnancy-specific beta-1-glycoprotein (SP 1 ) have been studied for their suitability in immunoperoxidase staining and radioimmunoassay methodologies. These antibodies were useful in staining normal placentas, hydatidiform moles, invasive moles and choriocarcinomas. They showed good specificity, with minimal background staining, and will thus be superior to conventional polyclonal antisera in immunohistochemistry. However, the presently tested monoclonal anti-SP 1 antibodies were found not to be suitable for radioimmunoassay. (Auth.)
HeliscopeCAGE sequencing, Delve mapping and CAGE TSS aggregation - FANTOM5 | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us FANTOM...at) Data file File name: fantom5_new_experimental_details.zip File URL: ftp://ftp.biosciencedbc.jp/archive/fantom5/LATEST/fantom...osciencedbc.jp/archive/fantom5/datafiles/LATEST/basic/ File size: 2.5 TB Simple s...earch URL http://togodb.biosciencedbc.jp/togodb/view/fantom5_new_experimental_details#en Data acquisition me...thod - Data analysis method HeliScopeCAGE ( http://fantom.gsc.riken.jp/protocols/heliscope.html ) Delve (Ali
Update History of This Database - Arabidopsis Phenome Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us Arabidopsis Phenome Database Update History of This Database Date Update contents 2017/02/27 Arabidopsis Phenome Data...base English archive site is opened. - Arabidopsis Phenome Database (http://jphenom...e.info/?page_id=95) is opened. About This Database Database Description Download License Update History of This Database... Site Policy | Contact Us Update History of This Database - Arabidopsis Phenome Database | LSDB Archive ...
Archives: Ethiopian Journal of Environmental Studies and ...

African Journals Online (AJOL)

Items 1 - 50 of 54 ... Archives: Ethiopian Journal of Environmental Studies and Management. Journal Home > Archives: Ethiopian Journal of Environmental Studies and Management. Log in or Register to get access to full text downloads.
YAC clone information - RGP physicalmap | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available 08/lsdba.nbdc00318-06-002 Description of data contents YAC clones selected with DNA markers Data file File name: rgp_physical...map_yac_clones.zip File URL: ftp://ftp.biosciencedbc.jp/archive/rgp-physicalmap/LATEST/rgp_physical...sciencedbc.jp/togodb/view/rgp_physicalmap_yac_clones#en Data acquisition method YAC clones selected with RGP...rom. No. Chromosome number Region Region number Physical map image The file name of rice physical map Order ...bout This Database Database Description Download License Update History of This Database Site Policy | Contact Us YAC clone information - RGP physicalmap | LSDB Archive ...
Crosswalking EAD: Collaboration in Archival Description

Directory of Open Access Journals (Sweden)

Amy McCrory

2005-09-01

Full Text Available Different library departments must work together, both formally and informally, in implementing encoded archival description and in repackaging descriptive information about archival collections to other formats, particularly machine-readable cataloging. The authors, one a technical services librarian and the other a special collections archivist, describe their experiences collaborating in these processes at The Ohio State University. Although other institutions may differ in their organizational structure, the authors hope to provide technical guidance, as well as a model of collaboration between archivists and technical services personnel. Careful dialogue and planning are essential to transcend the traditional divide between archival and library descriptive practices and systems.
Digital archives. Alcune note

Directory of Open Access Journals (Sweden)

Francesca Zanella

2014-12-01

Full Text Available MoRE is a digital native museum where projects of artworks are exposed, and also a digital archive where documents about art projectsare collected. MoRE is a multi-layered platform where artists, curators, art historians confront each other collecting art projects, organizing their documentation and defining tools for the communication and surveys on the public. In this paper some critical referencesare identified, that constitute a model for the project as they reflect on the impact of the digital dimension on the transformation of the museum and archive.
Rhizobia symbiosis of seven leguminous species growing along Xindian riverbank of Northern Taiwan

Directory of Open Access Journals (Sweden)

Cheng-Tai Huang

2018-01-01

Full Text Available Legume-rhizobia symbioses of seven leguminous species growing along Xindian riverbank of Northern Taiwan were investigated in this study. These legumes form either determinate or indeterminate types of root nodules. The determinate nodules of Alysicarpus vaginalis, Desmodium. triflorum, D. heterophyllum, Sesbania cannabina and the indeterminate nodules of Mimosa pudica harbored bacteroids of morphological uniformity (length of 1-3 μm, while the indeterminate nodules of Crotalaria zanzibarica and Trifolium repens contained bacteroids of highly pleomorphism (size varying from 1 to 5 μm. The enclosed bacteria were isolated from respective nodules, and twenty slow-growing and nine fast-growing rhizobial isolates were recovered. The slow-growing isolates were classified to the genus Bradyrhizobium based on the 16S rRNA sequences, whereas the fast-growing rhizobia comprise four genera, Neorhizobium, Rhizobium, Cupriavidus and Paraburkholderia. Results of stable isotope analyses revealed that the seven leguminous species had similar and consistently negative δ15N values in leaves (mean of -1.2 ‰, whereas the values were positive (varying from 3.7 to 7.3 ‰ in the nodules. These values were significantly higher in the indeterminate nodules than those in the determinate ones. In addition, variations in the values of leaf δ13C (varying from -29 to -34‰ among the seven legumes were measured, indicating their photosynthetic water use efficiencies were different. This is the first field survey to report the rhizobial diversity and the nutrient relationships of sympatric legume in Taiwan.
Archives: Annals of Ibadan Postgraduate Medicine

African Journals Online (AJOL)

Items 1 - 29 of 29 ... Archives: Annals of Ibadan Postgraduate Medicine. Journal Home > Archives: Annals of Ibadan Postgraduate Medicine. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue ...
Northern European long term climate archives

Energy Technology Data Exchange (ETDEWEB)

Hohl, Veronica [Stockholm Univ. (Sweden)

2005-01-01

The Swedish Nuclear Fuel and Waste Management Company is responsible for the management and disposal of Sweden's radioactive waste. It is intended to deposit the spent nuclear fuel in a deep geological repository. This repository shall keep the radiotoxic material separated from humans and the environment for extended periods, from decades to millennia and possibly to geological timescales. During this time perspective climate induced changes such as shore-level displacement and evolution of permafrost and ice sheets are expected to occur which may affect the repository. The possible occurrence, extent and duration of these long-term changes, are therefore of interest when considering the assessment of repository performance and safety. The main climate parameters determining both surface and subsurface conditions are temperature and precipitation. As a result of the last advance of the Weichselian ice sheet only few geological archives exist, which contain information on past climatic conditions in Sweden before c 16,000 years BP. The purpose of this literature review is to compile and evaluate available information from Scandinavian, Northern and Central European geological archives, which record climatic conditions during the Weichselian time period. The compilation provides paleotemperature data sets, which may be used to explore the possible evolution of periglacial permafrost in Sweden. This report is a synopsis of 22 publications detailing climatic and environmental changes during the Weichselian time period in Northwestern Europe based on quantified paleotemperature records. Some of the data is presented as temperature curves which were digitised specifically for this report. The time range covered by the different publications varies considerably. Only few authors dealt with the whole Weichselian period and the majority cover only a few thousand years. This however is not considered to influence the reliability of the archives. The reason for the
Northern European long term climate archives

International Nuclear Information System (INIS)

Hohl, Veronica

2005-01-01

The Swedish Nuclear Fuel and Waste Management Company is responsible for the management and disposal of Sweden's radioactive waste. It is intended to deposit the spent nuclear fuel in a deep geological repository. This repository shall keep the radiotoxic material separated from humans and the environment for extended periods, from decades to millennia and possibly to geological timescales. During this time perspective climate induced changes such as shore-level displacement and evolution of permafrost and ice sheets are expected to occur which may affect the repository. The possible occurrence, extent and duration of these long-term changes, are therefore of interest when considering the assessment of repository performance and safety. The main climate parameters determining both surface and subsurface conditions are temperature and precipitation. As a result of the last advance of the Weichselian ice sheet only few geological archives exist, which contain information on past climatic conditions in Sweden before c 16,000 years BP. The purpose of this literature review is to compile and evaluate available information from Scandinavian, Northern and Central European geological archives, which record climatic conditions during the Weichselian time period. The compilation provides paleotemperature data sets, which may be used to explore the possible evolution of periglacial permafrost in Sweden. This report is a synopsis of 22 publications detailing climatic and environmental changes during the Weichselian time period in Northwestern Europe based on quantified paleotemperature records. Some of the data is presented as temperature curves which were digitised specifically for this report. The time range covered by the different publications varies considerably. Only few authors dealt with the whole Weichselian period and the majority cover only a few thousand years. This however is not considered to influence the reliability of the archives. The reason for the varying
Molecular imaging with 68Ga-SSTR PET/CT and correlation to immunohistochemistry of somatostatin receptors in neuroendocrine tumours

International Nuclear Information System (INIS)

Kaemmerer, Daniel; Haugvik, Sven-Petter; Hommann, Merten; Peter, Luisa; Lupp, Amelie; Schulz, Stefan; Saenger, Joerg; Prasad, Vikas; Kulkarni, Harshad; Baum, Richard Paul

2011-01-01

Somatostatin receptors (SSTR) are known for an overexpression in gastroenteropancreatic neuroendocrine tumours (GEP-NET). The aim of the present study was to find out if the receptor density predicted by the semi-quantitative parameters generated from the static positron emission tomography (PET/CT) correlated with the in vitro immunohistochemistry using a novel rabbit monoclonal anti-SSTR2A antibody (clone UMB-1) for specific SSTR2A immunohistochemistry and polyclonal antibodies for SSTR1 and 3-5. Overall 14 surgical specimens generated from 34 histologically documented GEP-NET patients were correlated with the preoperative 68 Ga-DOTA-NOC PET/CT. Quantitative assessment of the receptor density was done using the immunoreactive score (IRS) of Remmele and Stegner; the additional 4-point IRS classification for immunohistochemistry and standardized uptake values (SUV max and SUV mean ) were used for PET/CT. The IRS for SSTR2A and SSTR5 correlated highly significant with the SUV max on the PET/CT (p mean (p max on the 68 Ga-DOTA-NOC PET/CT scans is concordant with the affinity profile of 68 Ga-DOTA-NOC to the SSTR subtypes and demonstrates the excellent qualification of somatostatin analogues in the diagnostics of NET. This study correlating somatostatin receptor imaging using 68 Ga-DOTA-NOC PET/CT with immunohistochemically analysed SSTR also underlines the approval of therapy using somatostatin analogues, follow-up imaging as well as radionuclide therapy. (orig.)
Records Group. The problem of fonds in the American archival studies

Directory of Open Access Journals (Sweden)

Bartosz Nowożycki

2017-12-01

Full Text Available The term record group means a group of fonds (records and it is a type of archival fonds rarely described in Polish archival literature. Most often it is associated with the complex archival fonds, due to its comlicated structure and blurred borderlines – an effect of administrative system varying from the Polish one. The post-war attempts to modify and broaden the meaning of the complex fonds caused its resemblance to the term record group. Irena Radtke in her paper given during the 6th Archival Methods Conference in Warsaw in 1970 proposed, that the complex fonds should be one comprising records of foreign provenance that are an effect of passive succession. Bohdan Ryszewski, addressing Radtke’s idea, noticed that passive succession might be a source of complications. However, this conceptualization of the definition of the complex fonds did not correspond with the American understanding of it as an above-fonds structure.Bogdan Kroll has touched the core of the problem; he noticed that an archival construction comprising materials of various provenances cannot be seen neither as an archival fonds, nor as a complex fonds. He saw a discrepancy between the structure and partition of archival holdings and archival theory; thus Kroll proposed abandoning the term complex fonds and implementation of the term archival complex. The archival complex was supposed to be archival materials of various origins merged (in or outside of an archive into fonds, or parts of archival fonds of different institutions having the same characteristic – function. The complex was supposed to make up a separate entity in logic structure of archival holdings, comprising of all archival fonds and/or their pieces being parts of the main fonds of the complex. The problem of lack of above-fonds forms in the Polish archival theory has been also noticed by Józef Siemieński, who has formulated the term of higher-order fonds. According to his idea the higher
Update History of This Database - GenLibi | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us GenLibi Update History of This Database Date Update contents 2014/03/25 GenLibi English archi...base Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - GenLibi | LSDB Archive ... ...ve site is opened. 2007/03/01 GenLibi ( http://gene.biosciencedbc.jp/ ) is opened. About This Database Data
tRNA sequence data, annotation data and curation data - tRNADB-CE | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us tRNAD... tRNA sequence data, annotation data and curation data - tRNADB-CE | LSDB Archive ...
Acquisition, Preservation, and Retrieval of Archival Materials in the ...

African Journals Online (AJOL)

Information is a daily need of every person either for personal or official engagement which is obtainable from various sources including archives. This paper discusses the acquisition, preservation and retrieval of archival materials in the National Archives Kaduna, Nigeria. Case study approach was used for the study.
Conceptual Paper: Digital Preservation Strategies in Archival Institution

OpenAIRE

Ismail Adila; Bullah Affandy Habee

2018-01-01

In this paper, the overall overview of concept of preservation regardless if it is preservation of physical records/archives or digital records/archives is discussed. The concept of the preservation discussed includes preventive preservation, restorative preservation, and content preservation. Then the concept of digital preservation. Furthermore, this paper highlighted the strategies and methods used in implementing the preservation of digital records/archives. The issues those are involved ...
Using Rhythms of Relationships to Understand Email Archives

National Research Council Canada - National Science Library

Perer, Adam; Shneiderman, Ben; Oard, Douglas W

2005-01-01

...: analyzing the temporal rhythms of social relationships. We provide methods for constructing meaningful rhythms from the email headers by identifying relationships and interpreting their attributes. With these visualization techniques, email archive explorers can uncover insights that may have been otherwise hidden in the archive. We apply our methods to an individual's fifteen-year email archive, which consists of about 45,000 messages and over 4,000 relationships.
The PSI web interface to the EPICS channel archiver

International Nuclear Information System (INIS)

Gaudenz Jud; Luedeke, A.; Portmann, W.

2012-01-01

the EPICS (Experimental Physics and Industrial Control System) channel archiver is used at different facilities at PSI (Paul Scherrer Institute) like the Swiss Light Source or the medical cyclotron. The EPICS channel archiver is a powerful tool to collect control system data of thousands of EPICS process variables with rates of many Hertz each to an archive for later retrieval. Within the package of the channel archiver version 2 you get a Java application for graphical data retrieval and a command line tool for data extraction into different file formats. For the Paul Scherrer Institute (PSI) we wanted a possibility to retrieve the archived data from a web interface. It was desired to have flexible retrieval functions and to allow interchanging data references by e-mail. This web interface has been implemented by the PSI controls group and has now been in operation for several years. This paper will highlight the special features of the PSI web interface to the EPICS channel archiver
Application of LOD Technology in German Libraries and Archives

Directory of Open Access Journals (Sweden)

Dong Jie

2017-12-01

Full Text Available [Purpose/significance] Linked Open Data (LOD has been widely used in large industries, as well as non-profit organizations and government organizations. Libraries and archives are ones of the early adopters of LOD technology. Libraries and archives promote the development of LOD. Germany is one of the developed countries in the libraries and archives industry, and there are many successful cases about the application of LOD in the libraries and archives. [Method/process] This paper analyzed the successful application of LOD technology in German libraries and archives by using the methods of document investigation, network survey and content analysis. [Result/conclusion] These cases reveal in the traditional field of computer science the relationship among research topics related to libraries and archives such as artificial intelligence, database and knowledge discovery. Summing up the characteristics and experience of German practice can provide more reference value for the development of relevant practice in China.

Archive Notes: Travelling Africa & the Archives

OpenAIRE

Easton, Kai

2015-01-01

A brief introduction to a cluster of articles in the Journal of History and Culture which are revised from SOAS MA Travelling Africa archive projects (2012-13 cohort). \\ud \\ud Conference programmes /abstracts are also uploaded here from 2013, 2014, 2015 which illustrate the range of student projects for this postgraduate module.\\ud \\ud In 2013 we launched the event with guest researchers, whose titles/abstracts are also provided here.\\ud
Archives of Atmospheric Lead Pollution

Science.gov (United States)

Weiss, Dominik; Shotyk, William; Kempf, Oliver

Environmental archives such as peat bogs, sediments, corals, trees, polar ice, plant material from herbarium collections, and human tissue material have greatly helped to assess both ancient and recent atmospheric lead deposition and its sources on a regional and global scale. In Europe detectable atmospheric lead pollution began as early as 6000years ago due to enhanced soil dust and agricultural activities, as studies of peat bogs reveal. Increased lead emissions during ancient Greek and Roman times have been recorded and identified in many long-term archives such as lake sediments in Sweden, ice cores in Greenland, and peat bogs in Spain, Switzerland, the United Kingdom, and the Netherlands. For the period since the Industrial Revolution, other archives such as corals, trees, and herbarium collections provide similar chronologies of atmospheric lead pollution, with periods of enhanced lead deposition occurring at the turn of the century and since 1950. The main sources have been industry, including coal burning, ferrous and nonferrous smelting, and open waste incineration until c.1950 and leaded gasoline use since 1950. The greatest lead emissions to the atmosphere all over Europe occurred between 1950 and 1980 due to traffic exhaust. A marked drop in atmospheric lead fluxes found in most archives since the 1980s has been attributed to the phasing out of leaded gasoline. The isotope ratios of lead in the various archives show qualitatively similar temporal changes, for example, the immediate response to the introduction and phasing out of leaded gasoline. Isotope studies largely confirm source assessments based on lead emission inventories and allow the contributions of various anthropogenic sources to be calculated.
User requirements for access to Dutch spoken audio archives

NARCIS (Netherlands)

Heeren, W.F.L.

2008-01-01

Searching archived audiovisual collections will change in the near future. Instead of sifting through kilometers of analog tapes in archives' deposits, end users will be able to explore the collections from behind a personal computer, either at an archive or at their home. A first step in the
Archives as Extended Memory of Communities: The Case of ...

African Journals Online (AJOL)

Archives and the archivists are critical elements in the construction and reconstruction of social history. Archival institutions should not be viewed simply as repository institutions, but as this article argues, should be considered as extended memories of those communities whose records they house. It is through the archive ...
NADIR: A Flexible Archiving System Current Development

Science.gov (United States)

Knapic, C.; De Marco, M.; Smareglia, R.; Molinaro, M.

2014-05-01

The New Archiving Distributed InfrastructuRe (NADIR) is under development at the Italian center for Astronomical Archives (IA2) to increase the performances of the current archival software tools at the data center. Traditional softwares usually offer simple and robust solutions to perform data archive and distribution but are awkward to adapt and reuse in projects that have different purposes. Data evolution in terms of data model, format, publication policy, version, and meta-data content are the main threats to re-usage. NADIR, using stable and mature framework features, answers those very challenging issues. Its main characteristics are a configuration database, a multi threading and multi language environment (C++, Java, Python), special features to guarantee high scalability, modularity, robustness, error tracking, and tools to monitor with confidence the status of each project at each archiving site. In this contribution, the development of the core components is presented, commenting also on some performance and innovative features (multi-cast and publisher-subscriber paradigms). NADIR is planned to be developed as simply as possible with default configurations for every project, first of all for LBT and other IA2 projects.
A MYSQL-BASED DATA ARCHIVER: PRELIMINARY RESULTS

International Nuclear Information System (INIS)

Matthew Bickley; Christopher Slominski

2008-01-01

Following an evaluation of the archival requirements of the Jefferson Laboratory accelerator's user community, a prototyping effort was executed to determine if an archiver based on MySQL had sufficient functionality to meet those requirements. This approach was chosen because an archiver based on a relational database enables the development effort to focus on data acquisition and management, letting the database take care of storage, indexing and data consistency. It was clear from the prototype effort that there were no performance impediments to successful implementation of a final system. With our performance concerns addressed, the lab undertook the design and development of an operational system. The system is in its operational testing phase now. This paper discusses the archiver system requirements, some of the design choices and their rationale, and presents the acquisition, storage and retrieval performance
Archiving Reproducible Research with R and Dataverse

DEFF Research Database (Denmark)

Leeper, Thomas

2014-01-01

Reproducible research and data archiving are increasingly important issues in research involving statistical analyses of quantitative data. This article introduces the dvn package, which allows R users to publicly archive datasets, analysis files, codebooks, and associated metadata in Dataverse...
Update History of This Database - AcEST | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us AcEST Update History of This Database Date Update contents 2013/01/10 Errors found on AcEST ...s Database Database Description Download License Update History of This Data...base Site Policy | Contact Us Update History of This Database - AcEST | LSDB Archive ... ...Conting data have been correceted. For details, please refer to the following page. Data correction 2010/03/29 AcEST English archi
Sandia Data Archive (SDA) file specifications

Energy Technology Data Exchange (ETDEWEB)

Dolan, Daniel H. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ao, Tommy [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-02-01

The Sandia Data Archive (SDA) format is a specific implementation of the HDF5 (Hierarchal Data Format version 5) standard. The format was developed for storing data in a universally accessible manner. SDA files may contain one or more data records, each associated with a distinct text label. Primitive records provide basic data storage, while compound records support more elaborate grouping. External records allow text/binary files to be carried inside an archive and later recovered. This report documents version 1.0 of the SDA standard. The information provided here is sufficient for reading from and writing to an archive. Although the format was original designed for use in MATLAB, broader use is encouraged.
BAO Plate Archive Project

Science.gov (United States)

Mickaelian, A. M.; Gigoyan, K. S.; Gyulzadyan, M. V.; Paronyan, G. M.; Abrahamyan, H. V.; Andreasyan, H. R.; Azatyan, N. M.; Kostandyan, G. R.; Samsonyan, A. L.; Mikayelyan, G. A.; Farmanyan, S. V.; Harutyunyan, V. L.

2017-12-01

We present the Byurakan Astrophysical Observatory (BAO) Plate Archive Project that is aimed at digitization, extraction and analysis of archival data and building an electronic database and interactive sky map. BAO Plate Archive consists of 37,500 photographic plates and films, obtained with 2.6m telescope, 1m and 0.5m Schmidt telescopes and other smaller ones during 1947-1991. The famous Markarian Survey (or the First Byurakan Survey, FBS) 2000 plates were digitized in 2002-2005 and the Digitized FBS (DFBS, www.aras.am/Dfbs/dfbs.html) was created. New science projects have been conducted based on this low-dispersion spectroscopic material. Several other smaller digitization projects have been carried out as well, such as part of Second Byurakan Survey (SBS) plates, photographic chain plates in Coma, where the blazar ON 231 is located and 2.6m film spectra of FBS Blue Stellar Objects. However, most of the plates and films are not digitized. In 2015, we have started a project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage. Armenian Virtual Observatory (ArVO, www.aras.am/Arvo/arvo.htm) database will accommodate all new data. The project runs in collaboration with the Armenian Institute of Informatics and Automation Problems (IIAP) and will continues during 4 years in 2015-2018. The final result will be an Electronic Database and online Interactive Sky map to be used for further research projects. ArVO will provide all standards and tools for efficient usage of the scientific output and its integration in international databases.
Data archiving system implementation in ITER's CODAC Core System

Energy Technology Data Exchange (ETDEWEB)

Castro, R., E-mail: rodrigo.castro@visite.es [CIEMAT Fusion Program, Avda. Complutense 40, Madrid (Spain); Abadie, L. [ITER Organization, Route de Vinon-sur-Verdon, 13115 St. Paul-lez-Durance (France); Makushok, Y. [Sgenia, C/Chile, 4 Edificio II, Las Rozas, Madrid (Spain); Ruiz, M.; Sanz, D. [Instrumentation and Applied Acoustic Research Group, Technical University of Madrid, Madrid (Spain); Vega, J. [CIEMAT Fusion Program, Avda. Complutense 40, Madrid (Spain); Faig, J. [INDRA Sistemas, S.A. Unid. de Sistemas de Control, Dirección de Tecnología Energética, Madrid (Spain); Román-Pérez, G. [Sgenia, C/Chile, 4 Edificio II, Las Rozas, Madrid (Spain); Simrock, S.; Makijarvi, P. [ITER Organization, Route de Vinon-sur-Verdon, 13115 St. Paul-lez-Durance (France)

2015-10-15

Highlights: • Implementation of ITER's data archiving solution. • Integration of the solution into CODAC Core System. • Data archiving structure. • High efficient data transmission into fast plant system controllers. • Fast control and data acquisition in Linux. - Abstract: The aim of this work is to present the implementation of data archiving in ITER's CODAC Core System software. This first approach provides a client side API and server side software allowing the creation of a simplified version of ITERDB data archiving software, and implements all required elements to complete data archiving flow from data acquisition until its persistent storage technology. The client side includes all necessary components that run on devices that acquire or produce data, distributing and streaming to configure remote archiving servers. The server side comprises an archiving service that stores into HDF5 files all received data. The archiving solution aims at storing data coming for the data acquisition system, the conventional control and also processed/simulated data.
Troubleshooting Public Data Archiving: Suggestions to Increase Participation

Science.gov (United States)

Roche, Dominique G.; Lanfear, Robert; Binning, Sandra A.; Haff, Tonya M.; Schwanz, Lisa E.; Cain, Kristal E.; Kokko, Hanna; Jennions, Michael D.; Kruuk, Loeske E. B.

2014-01-01

An increasing number of publishers and funding agencies require public data archiving (PDA) in open-access databases. PDA has obvious group benefits for the scientific community, but many researchers are reluctant to share their data publicly because of real or perceived individual costs. Improving participation in PDA will require lowering costs and/or increasing benefits for primary data collectors. Small, simple changes can enhance existing measures to ensure that more scientific data are properly archived and made publicly available: (1) facilitate more flexible embargoes on archived data, (2) encourage communication between data generators and re-users, (3) disclose data re-use ethics, and (4) encourage increased recognition of publicly archived data. PMID:24492920
Update History of This Database - SKIP Stemcell Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us SKIP Stemcell Database Update History of This Database Date Update contents 2017/03/13 SKIP Stemcell Database... English archive site is opened. 2013/03/29 SKIP Stemcell Database ( https://www.skip.med.k...eio.ac.jp/SKIPSearch/top?lang=en ) is opened. About This Database Database Description Download License Update History of This Databa...se Site Policy | Contact Us Update History of This Database - SKIP Stemcell Database | LSDB Archive ...
BAG3 and HIF-1 α coexpression detected by immunohistochemistry correlated with prognosis in hepatocellular carcinoma after liver transplantation.

Science.gov (United States)

Xiao, Heng; Tong, Rongliang; Cheng, Shaobing; Lv, Zhen; Ding, Chaofeng; Du, Chengli; Xie, Haiyang; Zhou, Lin; Wu, Jian; Zheng, Shusen

2014-01-01

The objective is to determine the effects of BAG3 and HIF-1 α expression on the prognosis of HCC patients after liver transplantation. Samples from 31 patients with HCC receiving liver transplantation were collected for this study. The immunohistochemistry was used to detect the expression of BAG3 and HIF-1 α of HCC samples. According to the immunohistochemistry results, BAG3 and HIF-1 α staining were significantly associated with tumor TNM stage (P = 0.004, P = 0.012). A significant association between high BAG3/HIF-1 α levels and a shorter overall survival was detected, so as the combined BAG3 and HIF-1 α analysis. The results suggested that the expression level of BAG3 and HIF-1 α is efficient prognostic parameters in patients with HCC after liver transplantation.
Archive archaeology

DEFF Research Database (Denmark)

Mortensen, Eva

2017-01-01

With the rediscovery of Jerash in the 19th century as the starting point, this contribution focuses on the use of digital archives. Travel accounts, diaries, photographs, sketches and maps are to a large extent made publicly available online. Wishing to create an overview of the rediscovery...
Moving Archives

DEFF Research Database (Denmark)

Jørgensen, Anne Mette

narratives that often contain the emotion of pride and a sense of strong personal agency. These personal memories have not been inscribed in history books or museum exhibitions, they have not entered the archives, and their absence remains a problem for historical self-knowledge.Further, the dissertation...
Performing Archives: Reflections on Ways of not Being Dead in Public

Directory of Open Access Journals (Sweden)

Óscar Cornago

2014-12-01

Full Text Available The multiplication of the archives, as cultural practices and as a theoretical framework, has grown at the same rate as the suspicion about its usefulness. This paper proposes the idea of «performing archives» as a reaction to this suspicion. Through the concept of archive in Foucault and Agamben, on the one hand, and the Affects Archive project, on the other, different ways of understanding the performative dimension of archive are discussed.
Analysis of Croatian archives' web page from the perspective of public programmes

Directory of Open Access Journals (Sweden)

Goran Pavelin

2015-04-01

Full Text Available In order to remain relevant in society, archivists should promote collections and records that are kept in the archives. Through public programmes, archives interact with customers and various public actors and create the institutional image. This paper is concerned with the role of public programmes in the process of modernization of the archival practice, with the emphasis on the Croatian state archives. The aim of the paper is to identify what kind of information is offered to users and public in general on the web sites of the Croatian state archives. Public programmes involve two important components of archival practice: archives and users. Therefore, public programmes ensure good relations with the public. Croatian archivists still question the need for public relations in archives, while American and European archives have already integrated public relations into the basic archival functions. The key components needed for successful planning and implementation of public programs are the source of financing, compliance with the annual work plan, clear goals, defined target audience, cooperation and support from the local community, and the evaluation of results.
MINI REVIEW ARTICLE:Immunohistochemistry of Epithelioid Soft Tissue Sarcomas, Literature Review Based on Case Studies

Directory of Open Access Journals (Sweden)

Megha Joshi

2012-07-01

Full Text Available Neoplasms with epithelioid histology may be diagnostically challenging. Immunohisto chemistry (IHC can aid in confirming thedifferential diagnosis of mesotheliomas, melanomas, lymphomas, and soft tissue sarcomas, all tumors that can present with an epithelioid histology. Immunohistochemistry can also assist in confirming the type of sarcomas. Using cases diagnosed in acommunity hospital setting over a ten year period, the use of IHC in sarcomas will be illustrated.
Medical Archive Recording System (MARS)

OpenAIRE

Mohammad Reza Tajvidi

2007-01-01

In this talk, one of the most efficient, and reliable integrated tools for CD/DVD production workflow, called Medical Archive Recording System (MARS) by ETIAM Company, France, which is a leader in multimedia connectivity for healthcare in Europe, is going to be introduced. "nThis tool is used to record all patient studies, route the studies to printers and PACS automatically, print key images and associated reports and log all study production for automated post processing/archiving. Its...

Update History of This Database - Trypanosomes Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us Trypanosomes Database Update History of This Database Date Update contents 2014/05/07 The co...ntact information is corrected. The features and manner of utilization of the database are corrected. 2014/02/04 Trypanosomes Databas...e English archive site is opened. 2011/04/04 Trypanosomes Database ( http://www.tan...paku.org/tdb/ ) is opened. About This Database Database Description Download Lice...nse Update History of This Database Site Policy | Contact Us Update History of This Database - Trypanosomes Database | LSDB Archive ...
Double-labelling immunohistochemistry for MGMT and a “cocktail” of non-tumourous elements is a reliable, quick and easy technique for inferring methylation status in glioblastomas and other primary brain tumours

OpenAIRE

Burke, Elinor; Grobler, Mariana; Elderfield, Kay; Bond, Frances; Crocker, Matthew; Taylor, Rohan; Bridges, Leslie R

2013-01-01

Background Our aim was to develop a new protocol for MGMT immunohistochemistry with good agreement between observers and good correlation with molecular genetic tests of tumour methylation. We examined 40 primary brain tumours (30 glioblastomas and 10 oligodendroglial tumours) with our new technique, namely double-labelling immunohistochemistry for MGMT and a "cocktail" of non-tumour antigens (CD34, CD45 and CD68). We compared the results with single-labelling immunohistochemistry for MGMT an...
The challenge of archiving and preserving remotely sensed data

Directory of Open Access Journals (Sweden)

John L Faundeen

2003-10-01

Full Text Available Few would question the need to archive the scientific and technical (S&T data generated by researchers. At a minimum, the data are needed for change analysis. Likewise, most people would value efforts to ensure the preservation of the archived S&T data. Future generations will use analysis techniques not even considered today. Until recently, archiving and preserving these data were usually accomplished within existing infrastructures and budgets. As the volume of archived data increases, however, organizations charged with archiving S&T data will be increasingly challenged (U.S. General Accounting Office, 2002. The U.S. Geological Survey has had experience in this area and has developed strategies to deal with the mountain of land remote sensing data currently being managed and the tidal wave of expected new data. The Agency has dealt with archiving issues, such as selection criteria, purging, advisory panels, and data access, and has met with preservation challenges involving photographic and digital media. That experience has allowed the USGS to develop management approaches, which this paper outlines.
Exploiting Multimedia in Creating and Analysing Multimedia Web Archives

Directory of Open Access Journals (Sweden)

Jonathon S. Hare

2014-04-01

Full Text Available The data contained on the web and the social web are inherently multimedia and consist of a mixture of textual, visual and audio modalities. Community memories embodied on the web and social web contain a rich mixture of data from these modalities. In many ways, the web is the greatest resource ever created by human-kind. However, due to the dynamic and distributed nature of the web, its content changes, appears and disappears on a daily basis. Web archiving provides a way of capturing snapshots of (parts of the web for preservation and future analysis. This paper provides an overview of techniques we have developed within the context of the EU funded ARCOMEM (ARchiving COmmunity MEMories project to allow multimedia web content to be leveraged during the archival process and for post-archival analysis. Through a set of use cases, we explore several practical applications of multimedia analytics within the realm of web archiving, web archive analysis and multimedia data on the web in general.
The challenge of archiving and preserving remotely sensed data

Science.gov (United States)

Faundeen, John L.

2003-01-01

Few would question the need to archive the scientific and technical (S&T) data generated by researchers. At a minimum, the data are needed for change analysis. Likewise, most people would value efforts to ensure the preservation of the archived S&T data. Future generations will use analysis techniques not even considered today. Until recently, archiving and preserving these data were usually accomplished within existing infrastructures and budgets. As the volume of archived data increases, however, organizations charged with archiving S&T data will be increasingly challenged (U.S. General Accounting Office, 2002). The U.S. Geological Survey has had experience in this area and has developed strategies to deal with the mountain of land remote sensing data currently being managed and the tidal wave of expected new data. The Agency has dealt with archiving issues, such as selection criteria, purging, advisory panels, and data access, and has met with preservation challenges involving photographic and digital media. That experience has allowed the USGS to develop management approaches, which this paper outlines.
Problems and possibilities of digital newspaper and periodical archives

Directory of Open Access Journals (Sweden)

Thomas Smits

2014-12-01

Full Text Available Digital newspaper archives are the most widely used resource for digital humanities research. The basic functionality of these archives – the ability to perform keyword searches across multiple titles – is unlikely to change. This means that researchers can safely develop a digital methodology without having to fear that new technology will make their efforts obsolete. On the basis of this observation, this article discusses three methodological problems of the digital newspaper archive. First, it provides unequal access to both different scholars and historical periods. Second, it tends to ignore the historical form of media landscapes. Third, the digital mediation of newspapers and periodicals results in a problematic loss of context. This article proposes that the solution to these problems lies in the assertion of agency over the digital newspaper archive and in the debates surrounding them by researchers. They should see digital newspaper archive as any other paper archive: with its own possibilities and limitations, which can be adjusted by the researcher.
Archives: International Journal of Development and Policy Studies

African Journals Online (AJOL)

Archives: International Journal of Development and Policy Studies. Journal Home > Archives: International Journal of Development and Policy Studies. Log in or Register to get access to full text downloads.
Archives: Communicate: Journal of Library and Information Science

African Journals Online (AJOL)

Archives: Communicate: Journal of Library and Information Science. Journal Home > Archives: Communicate: Journal of Library and Information Science. Log in or Register to get access to full text downloads.
The Operation and Architecture of the Keck Observatory Archive

Science.gov (United States)

Berriman, G. B.; Gelino, C. R.; Laity, A.; Kong, M.; Swain, M.; Holt, J.; Goodrich, R.; Mader, J.; Tran, H. D.

2014-05-01

The Infrared Processing and Analysis Center (IPAC) and the W. M. Keck Observatory (WMKO) are collaborating to build an archive for the twin 10-m Keck Telescopes, located near the summit of Mauna Kea. The Keck Observatory Archive (KOA) takes advantage of IPAC's long experience with managing and archiving large and complex data sets from active missions and serving them to the community; and of the Observatory's knowledge of the operation of its sophisticated instrumentation and the organization of the data products. By the end of 2013, KOA will contain data from all eight active observatory instruments, with an anticipated volume of 28 TB. The data include raw science and observations, quick look products, weather information, and, for some instruments, reduced and calibrated products. The goal of including data from all instruments is the cumulation of a rapid expansion of the archive's holdings, and already data from four new instruments have been added since October 2012. One more active instrument, the integral field spectrograph OSIRIS, is scheduled for ingestion in December 2013. After preparation for ingestion into the archive, the data are transmitted electronically from WMKO to IPAC for curation in the physical archive. This process includes validation of the science and content of the data and verification that data were not corrupted in transmission. The archived data include both newly-acquired observations and all previously acquired observations. The older data extends back to the date of instrument commissioning; for some instruments, such as HIRES, these data can extend as far back as 1994. KOA will continue to ingest all newly obtained observations, at an anticipated volume of 4 TB per year, and plans to ingest data from two decommissioned instruments. Access to these data is governed by a data use policy that guarantees Principal Investigators (PI) exclusive access to their data for at least 18 months, and allows for extensions as granted by
18F-FAZA PET/CT in the Preoperative Evaluation of NSCLC: Comparison with 18F-FDG and Immunohistochemistry.

Science.gov (United States)

Mapelli, Paola; Bettinardi, Valentino; Fallanca, Federico; Incerti, Elena; Compierchio, Antonia; Rossetti, Francesca; Coliva, Angela; Savi, Annarita; Doglioni, Claudio; Negri, Giampiero; Gianolli, Luigi; Picchio, Maria

2018-01-01

To assess the capability of 18F-FAZA PET/CT in identifying intratumoral hypoxic areas in early and locally advanced non-small cell lung cancer (NSCLC) patients and to compare 18FFAZA PET/CT with 18F-FDG PET/CT and histopathological biomarkers and to investigate whether the assessment of tumour to blood (T/B) and tumour to muscle (T/M) ratios provide comparable information regarding the hypoxic fractions of the tumour. Seven patients with NSCLC were prospectively enrolled (3 men, 4 women; median age: 71 years; range 63-80). All patients underwent to 18F-FDG PET/CT and 18F-FAZA PET/CT before surgery. Maximum standardized uptake value (SUVmax) was used to evaluate 18FFDG PET/CT images, while 18F-FAZA PET/CT images have been interpreted by using tumour-toblood (T/B) and tumour-to-muscle (T/M) ratio. Surgery was performed in all patients; immunohistochemical analysis for hypoxia biomarkers was performed on histologic tumor samples. All lung lesions showed intense 18F-FDG uptake (mean SUVmax: 7.35; range: 2.35-25.20). A faint 18F-FAZA uptake was observed in 6/7 patients (T/B < 1.2) while significant uptake was present in the remaining 1/7 (T/B and T/M=2.24). On both 2 and 4 h imaging after injection, no differences were observed between T/M and T/B (p=0.5), suggesting that both blood and muscle are equivalent in estimating the background activity for image analysis. Immunohisotchemical analysis showed low or absent staining for hypoxia biomarkers in 3 patients (CA-IX and GLUT-1: 0%; HIF-1α: mean 3.3%; range 0-10). Two patients showed staining for HIF-1α of 5%, with CA-IX being 60% and 30%, respectively and GLUT-1 being 30% and 80%, respectively; in 1/7 HIF-1α was 10%, CA-IX was 50% and GLUT-1 was 90%. In one patient a higher percentage of HIF-1α and CA-IX (20% and 70%, respectively) positive cells was present, with GLUT-1 being 30%. To the best of our knowledge, this is the first paper assessing hypoxia and glucose metabolism in comparison with immunohistochemistry
Immunohistochemistry for predictive biomarkers in non-small cell lung cancer.

Science.gov (United States)

Mino-Kenudson, Mari

2017-10-01

In the era of targeted therapy, predictive biomarker testing has become increasingly important for non-small cell lung cancer. Of multiple predictive biomarker testing methods, immunohistochemistry (IHC) is widely available and technically less challenging, can provide clinically meaningful results with a rapid turn-around-time and is more cost efficient than molecular platforms. In fact, several IHC assays for predictive biomarkers have already been implemented in routine pathology practice. In this review, we will discuss: (I) the details of anaplastic lymphoma kinase (ALK) and proto-oncogene tyrosine-protein kinase ROS (ROS1) IHC assays including the performance of multiple antibody clones, pros and cons of IHC platforms and various scoring systems to design an optimal algorithm for predictive biomarker testing; (II) issues associated with programmed death-ligand 1 (PD-L1) IHC assays; (III) appropriate pre-analytical tissue handling and selection of optimal tissue samples for predictive biomarker IHC.
CERN’s Archive

CERN Multimedia

Bennett, Sophia Elizabeth

2017-01-01

The CERN Archive exists in the background, supporting other endeavours and preserving CERN’s documentary heritage for future generations. It is a place to find information on all aspects of CERN’s history
The National Arts Education Archive: Ideas and Imaginings

OpenAIRE

Adams, Jeff; Bailey, Rowan; Walton, Neil

2017-01-01

The National Arts Education Archive (NAEA) is housed and maintained by the Yorkshire Sculpture Park (YSP), and managed by YSP coordinators and educators with a well-established volunteer programme. This year, 2017, as part of the celebrations of the YSP’s 40th anniversary, the Archive will hold its own exhibition entitled Treasures Revealed: a collection of items selected by people who\\ud have been involved in the Archive, whether as donors, volunteers, researchers, artists, trustees or steer...
Archives: African Journal of Applied Zoology and Environmental ...

African Journals Online (AJOL)

Archives: African Journal of Applied Zoology and Environmental Biology. Journal Home > Archives: African Journal of Applied Zoology and Environmental Biology. Log in or Register to get access to full text downloads.
Analysis on Big Data Problems and Technique Supports of Archives Informatization

Directory of Open Access Journals (Sweden)

Du Xiaoyan

2017-06-01

Full Text Available [Purpose/significance] The realistic questions of the archives informatization management are faced with data size rapidly increasing, and their types and structures more diverse and complex. [Method/process] Based on the essential attribute of archives in this paper, the big data characteristics of digital archives in their storage and utilization links were analyzed, and the support of new big data techniques in the course of archives informatization, and their applications to the storage and utilization of digital archives and knowledge discovery were researched. [Result/conclusion] Modern processing technology for big data would not only bring certain supports for the management of archives informatization, but also promote the development of its theory and practice.
Interoperability at ESA Heliophysics Science Archives: IVOA, HAPI and other implementations

Science.gov (United States)

Martinez-Garcia, B.; Cook, J. P.; Perez, H.; Fernandez, M.; De Teodoro, P.; Osuna, P.; Arnaud, M.; Arviset, C.

2017-12-01

The data of ESA heliophysics science missions are preserved at the ESAC Science Data Centre (ESDC). The ESDC aims for the long term preservation of those data, which includes missions such as Ulysses, Soho, Proba-2, Cluster, Double Star, and in the future, Solar Orbiter. Scientists have access to these data through web services, command line and graphical user interfaces for each of the corresponding science mission archives. The International Virtual Observatory Alliance (IVOA) provides technical standards that allow interoperability among different systems that implement them. By adopting some IVOA standards, the ESA heliophysics archives are able to share their data with those tools and services that are VO-compatible. Implementation of those standards can be found in the existing archives: Ulysses Final Archive (UFA) and Soho Science Archive (SSA). They already make use of VOTable format definition and Simple Application Messaging Protocol (SAMP). For re-engineered or new archives, the implementation of services through Table Access Protocol (TAP) or Universal Worker Service (UWS) will leverage this interoperability. This will be the case for the Proba-2 Science Archive (P2SA) and the Solar Orbiter Archive (SOAR). We present here which IVOA standards were already used by the ESA Heliophysics archives in the past and the work on-going.
Remediation of the protein data bank archive.

NARCIS (Netherlands)

Henrick, K.; Feng, Z.; Bluhm, W.F.; Dimitropoulos, D.; Doreleijers, J.; Dutta, S.; Flippen-Anderson, J.L.; Ionides, J.; Kamada, C.; Krissinel, E.; Lawson, C.L.; Markley, J.L.; Nakamura, H.; Newman, R.; Shimizu, Y.; Swaminathan, J.; Velankar, S.; Ory, J.; Ulrich, E.L.; Vranken, W; Westbrook, J.; Yamashita, R.; Yang, H.; Young, J.; Yousufuddin, M.; Berman, H.M.

2008-01-01

The Worldwide Protein Data Bank (wwPDB; wwpdb.org) is the international collaboration that manages the deposition, processing and distribution of the PDB archive. The online PDB archive at ftp://ftp.wwpdb.org is the repository for the coordinates and related information for more than 47 000
LBT Distributed Archive: Status and Features

Science.gov (United States)

Knapic, C.; Smareglia, R.; Thompson, D.; Grede, G.

2011-07-01

After the first release of the LBT Distributed Archive, this successful collaboration is continuing within the LBT corporation. The IA2 (Italian Center for Astronomical Archive) team had updated the LBT DA with new features in order to facilitate user data retrieval while abiding by VO standards. To facilitate the integration of data from any new instruments, we have migrated to a new database, developed new data distribution software, and enhanced features in the LBT User Interface. The DBMS engine has been changed to MySQL. Consequently, the data handling software now uses java thread technology to update and synchronize the main storage archives on Mt. Graham and in Tucson, as well as archives in Trieste and Heidelberg, with all metadata and proprietary data. The LBT UI has been updated with additional features allowing users to search by instrument and some of the more important characteristics of the images. Finally, instead of a simple cone search service over all LBT image data, new instrument specific SIAP and cone search services have been developed. They will be published in the IVOA framework later this fall.
Planetary Data Archiving Plan at JAXA

Science.gov (United States)

Shinohara, Iku; Kasaba, Yasumasa; Yamamoto, Yukio; Abe, Masanao; Okada, Tatsuaki; Imamura, Takeshi; Sobue, Shinichi; Takashima, Takeshi; Terazono, Jun-Ya

After the successful rendezvous of Hayabusa with the small-body planet Itokawa, and the successful launch of Kaguya to the moon, Japanese planetary community has gotten their own and full-scale data. However, at this moment, these datasets are only available from the data sites managed by each mission team. The databases are individually constructed in the different formats, and the user interface of these data sites is not compatible with foreign databases. To improve the usability of the planetary archives at JAXA and to enable the international data exchange smooth, we are investigating to make a new planetary database. Within a coming decade, Japan will have fruitful datasets in the planetary science field, Venus (Planet-C), Mercury (BepiColombo), and several missions in planning phase (small-bodies). In order to strongly assist the international scientific collaboration using these mission archive data, the planned planetary data archive at JAXA should be managed in an unified manner and the database should be constructed in the international planetary database standard style. In this presentation, we will show the current status and future plans of the planetary data archiving at JAXA.
Isolation of Borrelia burgdorferi from the blood of seven patients with Lyme disease.

Science.gov (United States)

Nadelman, R B; Pavia, C S; Magnarelli, L A; Wormser, G P

1990-01-01

Borrelia burgdorferi, the etiologic agent of Lyme disease, has rarely been successfully cultured from blood. We report on seven patients from Westchester County, New York, with B. burgdorferi bacteremia diagnosed between April 1987 and August 1987. One hundred thirty-two attempts to isolate spirochetes were made on blood specimens obtained from 104 patients. Twenty-two of these specimens were obtained from nine patients who had recently been bitten by Ixodes ticks but who were asymptomatic. Heparinized blood or serum specimens (0.2 to 0.4 mL) were inoculated onto 6 mL of modified Barbour-Stoenner-Kelly medium. Lyme serology was performed by enzyme-linked immunosorbent polyvalent, IgM, and IgG assays, fluorescent immunoassay, and microhemagglutination. Four of the seven patients had erythema migrans, two had facial nerve palsy, and one had a flu-like syndrome without rash. These patients represented 21% (four of 19) of all patients with the characteristic skin lesion who had blood cultures for B. burgdorferi, and 40% (two of five) of all those with facial nerve palsy. Serologic testing was frequently nonreactive; two patients had no detectable antibody on multiple sera by five different assays. All patients improved with antibiotic treatment, and had negative subsequent blood cultures, but five of seven had persistent complaints after completion of therapy. Culturing blood for B. burgdorferi may be useful in confirming the diagnosis of Lyme disease in selected patients. Use of spirochete blood cultures may facilitate a better understanding of the pathogenesis and natural history of Lyme disease.

LSDB Archive - KEGG MEDICUS | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available [ Credits ] English ]; } else if ( url.search(//en//) != -1 ) { url = url.replace(/...switchLanguage; BLAST Search Image Search Home About Archive Update History Data List Contact us KEGG MEDI...CUS Database Description General information of database Database name KEGG MEDICUS...ug design Organism Taxonomy Name: Human Taxonomy ID: 9606 Database description KEGG MEDICUS is an integrated...ge inserts) of all marketed drugs in Japan and the USA are integrated with the KEGG DRUG and KEGG DISEASE databases in KEGG MEDI
A monoclonal antibody to inclusion body disease of cranes virus enabling specific immunohistochemistry and competitive ELISA

Science.gov (United States)

Letchworth, G.J.; Fishel, J.R.; Hansen, W.R.

1997-01-01

Inclusion body disease of cranes (IBDC) herpesvirus kills some infected cranes and persists in convalescent animals. To enable further study and rapid identification of carrier animals, we developed a monoclonal antibody (MAb) to IBDC virus and used it in immunohistochemistry and a competitive enzyme-linked immunosorbent assay (ELISA). We used conventional techniques to make murine MAbs directed against IBDC virus purified from infected duck embryo cells. Hybridomas reacting in an ELISA with IBDC virus but not uninfected duck embryo cells were characterized by radioimmunoprecipitation, in situ immunohistochemistry, and competitive ELISA with neutralizing and nonneutralizing crane sera. MAb 2C11 immunoprecipitated 59-, 61-, and 110-kD proteins from IBDC virus-infected but not uninfected cells and stained glutaraldehyde-fixed IBDC virus plaques but not surrounding uninfected duck embryo cells in vitro. Antibody 2C11 did not react with duck embryo cells infected with falcon herpesvirus, psittacine herpesvirus, infectious laryngotracheitis, pigeon herpesvirus, or duck plague virus. A competitive ELISA using antibody 2C11 identified most sera that were positive in the neutralization test. This antibody will be useful in further characterizing IBDC virus, its pathogenesis, and its natural history.
Automated Metadata Extraction for Semantic Access to Spoken Word Archives

NARCIS (Netherlands)

de Jong, Franciska M.G.; Heeren, W.F.L.; van Hessen, Adrianus J.; Ordelman, Roeland J.F.; Nijholt, Antinus; Ruiz Miyares, L.; Alvarez Silva, M.R.

2011-01-01

Archival practice is shifting from the analogue to the digital world. A specific subset of heritage collections that impose interesting challenges for the field of language and speech technology are spoken word archives. Given the enormous backlog at audiovisual archives of unannotated materials and
BAG3 and HIF-1α Coexpression Detected by Immunohistochemistry Correlated with Prognosis in Hepatocellular Carcinoma after Liver Transplantation

Directory of Open Access Journals (Sweden)

Heng Xiao

2014-01-01

Full Text Available Objective. The objective is to determine the effects of BAG3 and HIF-1α expression on the prognosis of HCC patients after liver transplantation. Methods. Samples from 31 patients with HCC receiving liver transplantation were collected for this study. The immunohistochemistry was used to detect the expression of BAG3 and HIF-1α of HCC samples. Results. According to the immunohistochemistry results, BAG3 and HIF-1α staining were significantly associated with tumor TNM stage (P=0.004, P=0.012. A significant association between high BAG3/HIF-1α levels and a shorter overall survival was detected, so as the combined BAG3 and HIF-1α analysis. Conclusion. The results suggested that the expression level of BAG3 and HIF-1α is efficient prognostic parameters in patients with HCC after liver transplantation.
Digital video recording and archiving in ophthalmic surgery

Directory of Open Access Journals (Sweden)

Raju Biju

2006-01-01

Full Text Available Currently most ophthalmic operating rooms are equipped with an analog video recording system [analog Charge Couple Device camera for video grabbing and a Video Cassette Recorder for recording]. We discuss the various advantages of a digital video capture device, its archiving capabilities and our experience during the transition from analog to digital video recording and archiving. The basic terminology and concepts related to analog and digital video, along with the choice of hardware, software and formats for archiving are discussed.
Quantifying retrieval bias in Web archive search

NARCIS (Netherlands)

Samar, Thaer; Traub, Myriam C.; van Ossenbruggen, Jacco; Hardman, Lynda; de Vries, Arjen P.

2018-01-01

A Web archive usually contains multiple versions of documents crawled from the Web at different points in time. One possible way for users to access a Web archive is through full-text search systems. However, previous studies have shown that these systems can induce a bias, known as the
Archives: Journal of Technology and Education in Nigeria

African Journals Online (AJOL)

Items 1 - 18 of 18 ... Archives: Journal of Technology and Education in Nigeria. Journal Home > Archives: Journal of Technology and Education in Nigeria. Log in or Register to get access to full text downloads.
Archives: International Journal of Biological and Chemical Sciences

African Journals Online (AJOL)

Items 1 - 50 of 61 ... Archives: International Journal of Biological and Chemical Sciences. Journal Home > Archives: International Journal of Biological and Chemical Sciences. Log in or Register to get access to full text downloads.
Archives: East and Central African Journal of Surgery

African Journals Online (AJOL)

Items 1 - 40 of 40 ... Archives: East and Central African Journal of Surgery. Journal Home > Archives: East and Central African Journal of Surgery. Log in or Register to get access to full text downloads.
Archives: Western Indian Ocean Journal of Marine Science

African Journals Online (AJOL)

Items 1 - 29 of 29 ... Archives: Western Indian Ocean Journal of Marine Science. Journal Home > Archives: Western Indian Ocean Journal of Marine Science. Log in or Register to get access to full text downloads.
Archives: Tanzania Journal of Forestry and Nature Conservation

African Journals Online (AJOL)

Items 1 - 18 of 18 ... Archives: Tanzania Journal of Forestry and Nature Conservation. Journal Home > Archives: Tanzania Journal of Forestry and Nature Conservation. Log in or Register to get access to full text downloads.
Archives: Journal of Computer Science and Its Application

African Journals Online (AJOL)

Items 1 - 9 of 9 ... Archives: Journal of Computer Science and Its Application. Journal Home > Archives: Journal of Computer Science and Its Application. Log in or Register to get access to full text downloads.
Oral History Archives | Fellowship | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Fellowship; Oral History Archives. Oral history archive ... video documentaries of some of the leading scientists of the country from among Academy's fellowship. ... Math Art and Design: MAD about Math, Math Education and Outreach.
Archives: Journal of Agriculture and Social Research (JASR)

African Journals Online (AJOL)

Items 1 - 24 of 24 ... Archives: Journal of Agriculture and Social Research (JASR). Journal Home > Archives: Journal of Agriculture and Social Research (JASR). Log in or Register to get access to full text downloads.
Archives: Bayero Journal of Pure and Applied Sciences

African Journals Online (AJOL)

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Archives: African Journal of Environmental Science and Technology

African Journals Online (AJOL)

Items 1 - 50 of 117 ... Archives: African Journal of Environmental Science and Technology. Journal Home > Archives: African Journal of Environmental Science and Technology. Log in or Register to get access to full text downloads.
Archives: Nigeria Journal of Pure and Applied Physics

African Journals Online (AJOL)

Items 1 - 6 of 6 ... Archives: Nigeria Journal of Pure and Applied Physics. Journal Home > Archives: Nigeria Journal of Pure and Applied Physics. Log in or Register to get access to full text downloads.
Bleaching of melanin in the epidermis of South American fur seal and its application on enzyme immunohistochemistry

Directory of Open Access Journals (Sweden)

A.P. Silva

2011-03-01

Full Text Available The South American fur seal (Arctocephalus australis is an amphibious marine mammal distributed along the Atlantic and Pacific coasts of South America. The species is well adjusted to different habitats due to the morphology of its fin-like members and due to some adaptations in their integumentary system. Immunohistochemical studies are very important to evaluate the mechanisms of skin adaptation due the differential expression of the antigens present in the tissue depending of the region of the body surface. However, its strongly pigmented (melanin epidermis prevents the visualization of the immuno-histochemical chromogens markers. In this study a melanin bleaching method was developed aimed to allow the visualization of the chromogens without interfering in the antigen-antibody affinity for immunohistochemistry. The analysis of PCNA (proliferating cell nuclear antigen index in the epidermis of A. australis by immunohistochemistry with diaminobenzidine (DAB as chromogen was used to test the method. The bleaching of the melanin allowed to obtain the cell proliferation index in epidermis and to avoid false positive results without affecting the immunohistochemical results.
News from the Library: The CERN Web Archive

CERN Multimedia

CERN Library

2012-01-01

The World Wide Web was born at CERN in 1989. However, although historic paper documents from over 50 years ago survive in the CERN Archive, it is by no means certain that we will be able to consult today's web pages 50 years from now. The Internet Archive's Wayback Machine includes an impressive collection of archived CERN web pages from 1996 onwards. However, their coverage is not complete - they aim for broad coverage of the whole Internet, rather than in-depth coverage of particular organisations. To try to fill this gap, the CERN Archive has entered into a partnership agreement with the Internet Memory Foundation. Harvesting of CERN's publicly available web pages is now being carried out on a regular basis, and the results are available here.
NASA's astrophysics archives at the National Space Science Data Center

Science.gov (United States)

Vansteenberg, M. E.

1992-01-01

NASA maintains an archive facility for Astronomical Science data collected from NASA's missions at the National Space Science Data Center (NSSDC) at Goddard Space Flight Center. This archive was created to insure the science data collected by NASA would be preserved and useable in the future by the science community. Through 25 years of operation there are many lessons learned, from data collection procedures, archive preservation methods, and distribution to the community. This document presents some of these more important lessons, for example: KISS (Keep It Simple, Stupid) in system development. Also addressed are some of the myths of archiving, such as 'scientists always know everything about everything', or 'it cannot possibly be that hard, after all simple data tech's do it'. There are indeed good reasons that a proper archive capability is needed by the astronomical community, the important question is how to use the existing expertise as well as the new innovative ideas to do the best job archiving this valuable science data.

Enlivening Dance History Pedagogy through Archival Projects

Science.gov (United States)

Randall, Tresa

2012-01-01

Dance archives can bring students into contact with historical subjects through artifacts of the past. This article advocates the use of archival projects in undergraduate dance history courses, arguing that such hands-on learning activities give students dynamic and interactive experiences of history. The author describes a creative project she…
Archives: Afrique Science: Revue Internationale des Sciences et ...

African Journals Online (AJOL)

Items 1 - 31 of 31 ... Archives: Afrique Science: Revue Internationale des Sciences et Technologie. Journal Home > Archives: Afrique Science: Revue Internationale des Sciences et Technologie. Log in or Register to get access to full text downloads.
An Introduction to Archival Automation: A RAMP Study with Guidelines.

Science.gov (United States)

Cook, Michael

Developed under a contract with the International Council on Archives, these guidelines are designed to emphasize the role of automation techniques in archives and records services, provide an indication of existing computer systems used in different archives services and of specific computer applications at various stages of archives…
Management innovative practices for archives and special collections

CERN Document Server

Theimer, Kate

2014-01-01

Management: Innovative Practices for Archives and Special Collections explores the kinds of challenges that managers of archival programs face today and how those challenges can be met to achieve optimal results while working within existing resources. The book features thirteen case studies that demonstrate solutions to both traditional management concerns as well as new issues and opportunities presented by changes in technology and organizational environments. This book will help professionals build stronger archival programs by making effective use of people, technology, and resources whil
Clustering results - Gclust Server | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us Gclust Server Clustering results Data detail Data name Clustering results DOI 10.18908/lsdba...se Update History of This Database Site Policy | Contact Us Clustering results - Gclust Server | LSDB Archive ...
Archiving Online Do-It-Yourself Culture

DEFF Research Database (Denmark)

Roued-Cunliffe, Henriette

This paper presents the argument that it is important to consider how information collected, created and shared by DIY culture online (using the case study of refashioning) can be archived and disseminated in future.......This paper presents the argument that it is important to consider how information collected, created and shared by DIY culture online (using the case study of refashioning) can be archived and disseminated in future....
Archives: South African Journal of Animal Science

African Journals Online (AJOL)

Items 1 - 50 of 185 ... Archives: South African Journal of Animal Science. Journal Home > Archives: South African Journal of Animal Science. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue ...
Archives: Nnamdi Azikiwe University Journal of International Law ...

African Journals Online (AJOL)

Items 1 - 11 of 11 ... Archives: Nnamdi Azikiwe University Journal of International Law and Jurisprudence. Journal Home > Archives: Nnamdi Azikiwe University Journal of International Law and Jurisprudence. Log in or Register to get access to full text downloads.
70 years of EDF archives and a lot more

International Nuclear Information System (INIS)

Holgado, S.

2016-01-01

Since 1968 'EDF Archives' has been in charge of collecting and preserving EDF's documents. EDF distinguishes 2 types of documents: documents (including data) that are still used by EDF teams in their daily work for knowledge transmission or legal aspects and earlier materials that are used for research works in history, sociology or economics. EDF being a public limited liability company (SA) with a public service mission, its archives are both private and public. The oldest documents date back in the 19. century as a legacy of the 2400 enterprises producing or transporting or dispatching electricity or gas that were nationalized in 1946 to form the EDF company. EDF's archives represent 100 linear kilometers of documents, 8 kilometers of which can be consulted by the public. In 2015 a club of the archivists from the nuclear industry was created, its aims were to manage common archives, to build a mapping of all corporate archives and to harmonize managing rules. (A.C.)
The possibility of establishing a doctoral programme in archive studies

Directory of Open Access Journals (Sweden)

Waldemar Chorążyczewski

2013-03-01

Full Text Available Doctor studies have been included into formalised education system as a third cycle studies. In the light of ministerial regulations, the archive studies doctoral program ought to encompass classes on archives, methodology of sciences, didactics of higher education studies, the social role of an academic, conducting student internship. Does this mean, that a doctoral seminar in archive studies is excessive? On the contrary, the seminar seems to be the best place to bequeath knowledge and skills on methodology and the proper attitude of a scholar, in awareness of his or her role in the society.By these standards, the seminar should be understood not solely as a place to forge doctoral theses, but also as a site on which to conduct discussion with one's academic authorities and advisors and guest experts; it also should be the key class, taking up the most of the timetable. The validity of preparing an archivist for the role of a university teacher has been questioned.Both the profile of the doctor courses and observation of their effectiveness has led us to believe informal seminar to be the better way of doctoral education for archive students. Perhaps though, the kind of steps, that must be taken if doctor course on archive studies was to be created, is worth considering. Is there a chance, and, is it worth striving for the archive studies to be an independent department? It would not only mean opening doctor programmes, but also the right confer a PhD degree in Humanities, on the subject of archive studies, and not history, as it has hitherto been done. The archive studies have definite research subject, range and methodology. What is noticeable is a kind of archival sensitivity, that allows for all the users and all the purposes for using the resources to be on equal rights. Archive studies have matured, and it is ready to become an independent academic discipline. Thereby, it can be expected, that at last, it's maturity will be put to good
Update History of This Database - Yeast Interacting Proteins Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us Yeast Interacting Proteins Database Update History of This Database Date Update contents 201...0/03/29 Yeast Interacting Proteins Database English archive site is opened. 2000/12/4 Yeast Interacting Proteins Database...( http://itolab.cb.k.u-tokyo.ac.jp/Y2H/ ) is released. About This Database Database Description... Download License Update History of This Database Site Policy | Contact Us Update History of This Database... - Yeast Interacting Proteins Database | LSDB Archive ...
Realization of Data Archiving for CTBT Beijing National Data Centre

International Nuclear Information System (INIS)

Wang Juan; Shi Jianfang; Wang Xiaoming; Liu Junmin; Qiu Hongmao; Zhang Bo; Lu Yuanglei; Xu Jin

2009-01-01

It is very important issue for the large scale real time data processing system to archive data. The method of data are archiving in the paper is to facilitate the permanent storages and retrieval of all data arriving at the NDC. The data in the operation file system and the database references to the data in the operation database will be deleted automatically after the system has verified archived data is identical with original data. The data archiving operations have been realized in China National Data Center. (authors)
Description innovative practices for archives and special collections

CERN Document Server

Theimer, Kate

2014-01-01

Description: Innovative Practices for Archives and Special Collections explores how archives of different sizes and types can enhance the accessibility of their holdings. The book uses eleven case studies to demonstrate innovative ideas that could be transferred into many other settings. Readers can use these as models, sources of inspiration, or starting points for new discussions. The volume will be useful to those working in archives and special collections as well as other cultural heritage organizations, and provides ideas ranging from those that require long-term planning and coordinatio
Disembodied archives: The disconnectedness of records and archives management practices within the Pietermaritzburg Cluster of Theological Libraries, KwaZulu-Natal, South Africa

OpenAIRE

Garaba, Francis

2015-01-01

This article discusses the findings of a study that was conducted between February 2013 and November 2013 to determine the inter-connectedness between records and archives management practices for religious archives within the Pietermaritzburg Cluster of Theological libraries (PCTL). It is important to note that much of our national heritage is recorded in the archives of our religious institutions, hence the need to ensure that a continuum of care is provided for this Christian heritage from...
The GIK-Archive of sediment core radiographs with documentation

Science.gov (United States)

Grobe, Hannes; Winn, Kyaw; Werner, Friedrich; Driemel, Amelie; Schumacher, Stefanie; Sieger, Rainer

2017-12-01

The GIK-Archive of radiographs is a collection of X-ray negative and photographic images of sediment cores based on exposures taken since the early 1960s. During four decades of marine geological work at the University of Kiel, Germany, several thousand hours of sampling, careful preparation and X-raying were spent on producing a unique archive of sediment radiographs from several parts of the World Ocean. The archive consists of more than 18 500 exposures on chemical film that were digitized, geo-referenced, supplemented with metadata and archived in the data library PANGAEA®. With this publication, the images have become available open-access for use by the scientific community at https://doi.org/10.1594/PANGAEA.854841.
Hyperarchiver: an evolution of EPICS channel archiver

International Nuclear Information System (INIS)

Campo, M. del; Arredondo, I.; Jugo, J.; Giacchini, M.; Giovannini, L.

2012-01-01

Data storage is a primary issue in any research facility. In the EPICS middleware based accelerator community, Channel Archiver has been always considered the main reference. It works with Oracle and MySQL, probably the best well known relational databases. However, demanding requirements at minimum costs have fostered the development of a wide range of alternatives, like MDSPlus (Consorzio RFX), SciDB (BNL) or Hypertable (IFNF). This document launches a tool called HyperArchiver, which was firstly developed at IFNF (Italy) and eventually customised by ESS Bilbao (Spain). Based on a NoSQL database named Hypertable, it focuses on large data sets management with maximum scalability, reliability and performance. Besides the update and further customization made at ESS Bilbao, HyperArchiver is presented with a set of GUIs, in order to provide an easy use and integration with any general control system. A LabVIEW VI and two cross-platform PyQt GUIs for both Hypertable data retrieval and HyperArchiver control have been developed and successfully tested at ESS Bilbao. (author)
Infrastructural challenges on archives and recordkeeping at the ...

African Journals Online (AJOL)

Ngulup

special and cannot be sold on the market or purchased from vendors or inside bookshops. (Asogwa and ... The history of archival buildings at NAZ ..... usually thought that archive buildings should be situated in the urban centre, the seat of the.
Archive Inventory Management System (AIMS) — A Fast, Metrics Gathering Framework for Validating and Gaining Insight from Large File-Based Data Archives

Science.gov (United States)

Verma, R. V.

2018-04-01

The Archive Inventory Management System (AIMS) is a software package for understanding the distribution, characteristics, integrity, and nuances of files and directories in large file-based data archives on a continuous basis.
News from the ESO Science Archive Facility

Science.gov (United States)

Dobrzycki, A.; Arnaboldi, M.; Bierwirth, T.; Boelter, M.; Da Rocha, C.; Delmotte, N.; Forchì, V.; Fourniol, N.; klein Gebbinck, M.; Lange, U.; Mascetti, L.; Micol, A.; Moins, C.; Munte, C.; Pluciennik, C.; Retzlaff, J.; Romaniello, M.; Rosse, N.; Sequeiros, I. V.; Vuong, M.-H.; Zampieri, S.

2015-09-01

ESO Science Archive Facility (SAF) - one of the world's biggest astronomical archives - combines two roles: operational (ingest, tallying, safekeeping and distribution to observers of raw data taken with ESO telescopes and processed data generated both internally and externally) and scientific (publication and delivery of all flavours of data to external users). This paper presents the “State of the SAF.” SAF, as a living entity, is constantly implementing new services and upgrading the existing ones. We present recent and future developments related to the Archive's Request Handler and metadata handling as well as performance and usage statistics and trends. We also discuss the current and future datasets on offer at SAF.
Remediation of the protein data bank archive

Science.gov (United States)

Henrick, Kim; Feng, Zukang; Bluhm, Wolfgang F.; Dimitropoulos, Dimitris; Doreleijers, Jurgen F.; Dutta, Shuchismita; Flippen-Anderson, Judith L.; Ionides, John; Kamada, Chisa; Krissinel, Eugene; Lawson, Catherine L.; Markley, John L.; Nakamura, Haruki; Newman, Richard; Shimizu, Yukiko; Swaminathan, Jawahar; Velankar, Sameer; Ory, Jeramia; Ulrich, Eldon L.; Vranken, Wim; Westbrook, John; Yamashita, Reiko; Yang, Huanwang; Young, Jasmine; Yousufuddin, Muhammed; Berman, Helen M.

2008-01-01

The Worldwide Protein Data Bank (wwPDB; wwpdb.org) is the international collaboration that manages the deposition, processing and distribution of the PDB archive. The online PDB archive at ftp://ftp.wwpdb.org is the repository for the coordinates and related information for more than 47 000 structures, including proteins, nucleic acids and large macromolecular complexes that have been determined using X-ray crystallography, NMR and electron microscopy techniques. The members of the wwPDB–RCSB PDB (USA), MSD-EBI (Europe), PDBj (Japan) and BMRB (USA)–have remediated this archive to address inconsistencies that have been introduced over the years. The scope and methods used in this project are presented. PMID:18073189

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