WorldWideScience

Sample records for hypothetical 100-year peak

  1. 100 years of superconductivity

    CERN Document Server

    Rogalla, Horst

    2011-01-01

    Even a hundred years after its discovery, superconductivity continues to bring us new surprises, from superconducting magnets used in MRI to quantum detectors in electronics. 100 Years of Superconductivity presents a comprehensive collection of topics on nearly all the subdisciplines of superconductivity. Tracing the historical developments in superconductivity, the book includes contributions from many pioneers who are responsible for important steps forward in the field.The text first discusses interesting stories of the discovery and gradual progress of theory and experimentation. Emphasizi

  2. [Osteology--100 years].

    Science.gov (United States)

    Götte, S

    2001-10-01

    As is the case for many other subspecialties of medical science, osteology has developed in tandem with technological progress over the last 100 years. The discover of X-rays made visualization of the skeletal system possible. Progress in surgery and hygiene permitted examination and treatment of bones in vivo. Optical techniques made it possible to gain insight into the microarchitecture of the bone. Chemistry and biochemistry opened the door for pathophysiology and microcellular assessment of the bone so that modern osteology deals with interventions in cellular mechanisms, in particular for the treatment of bone diseases. The realization that the bone represents a dynamic tissue, characterized by processes of generation and degeneration, was decisive. These events have a profound influence on the treatment of osteoporosis. Questions pertaining to osteology have been subject to heightened interdisciplinary debate in the past few years, which is reflected in interdisciplinary associations and co-operative groups, and ultimately the umbrella Society of Osteology. Contemplation of the subject from an interdisciplinary viewpoint shows what a significant and natural role orthopedics plays in research on bone metabolism, but also in the treatment of bone diseases. Interdisciplinary cooperation aids quality control and is also reflected in the formulation of common guidelines for the clinical picture of osteoporosis, which constitutes a major epidemiological disease.

  3. 100 Years of General Relativity

    CERN Document Server

    Ellis, George F R

    2015-01-01

    This is Chapter 1 in the book General Relativity and Gravitation: A Centennial Perspective, Edited by Abhay Ashtekar (Editor in Chief), Beverly Berger, James Isenberg, Malcolm MacCallum. Publisher: Cambridge University Press (June, 2015). It gives a survey of themes that have been developed during the 100 years of progress in general relativity theory.

  4. Hypothetical Justifications

    Directory of Open Access Journals (Sweden)

    Bernd Lahno

    2009-01-01

    Full Text Available A basic conviction in moral non-cognitivism is: only hypothetical norms may be justified. Hartmut Kliemt argues for a moderate variant: there are only hypothetical justifications of norms whether the norms are hypothetical or categorical in kind. In this paper the concept of 'hypothetical justification' is analyzed. It is argued that hypothetical justifications are not of the kind that we should look for in normative ethics.

  5. 100-Year Floodplains, 100 Year Floodplains, Published in 2007, Not Applicable scale, Dunn County, WI.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at Not Applicable scale, was produced all or in part from LIDAR information as of 2007. It is described as '100 Year...

  6. Energizer keep going: 100 years of superconductivity

    Institute of Scientific and Technical Information of China (English)

    Pengcheng Dai; Xing-jiang Zhou; Dao-xin Yao

    2011-01-01

    It has been 100 years since Heike Kamerlingh Onnes discovered superconductivity on April 8,1911.Amazingly,this field is still very active and keeps booming,like a magic.A lot of new phenomena and materials have been found,and superconductors have been used in many different fields to improve our lives.Onnes won the Nobel Prize for this incredible discovery in 1913 and used the word superconductivity for the first time.Onnes believed that quantum mechanics would explain the effect,but he could not produce a theory at that time.Now we know superconductivity is a macroscopic quantum phenomenon.

  7. Analysis of 100 Years of Curriculum Designs

    Directory of Open Access Journals (Sweden)

    Lynn Kelting-Gibson

    2013-01-01

    Full Text Available Fifteen historical and contemporary curriculum designs were analyzed for elements of assessment that support student learning and inform instructional decisions. Educational researchers are purposely paying attention to the role assessment plays in a well-designed planning and teaching process. Assessment is a vital component to educational planning and teaching because it is a way to gather accurate evidence of student learning and information to inform instructional decisions. The purpose of this review was to analyze 100 years of curriculum designs to uncover elements of assessment that will support teachers in their desire to improve student learning. Throughout this research the author seeks to answer the question: Do historical and contemporary curriculum designs include elements of assessment that help teachers improve student learning? The results of the review reveal that assessment elements were addressed in all of the curricular designs analyzed, but not all elements of assessment were identified using similar terminology. Based on the analysis of this review, it is suggested that teachers not be particular about the terminology used to describe assessment elements, as all curriculum models discussed use one or more elements similar to the context of pre, formative, and summative assessments.

  8. [Radical prostatectomy--100 years of evolution].

    Science.gov (United States)

    Gofrit, Ofer N; Shalhav, Arieh L

    2008-07-01

    Prostate cancer is the most common malignant disease in men. The incidence of prostate cancer has been rising since the early 1990s. Not all men inflicted by prostate cancer will develop clinical disease. Therefore, sorting these cases is a great clinical challenge. Radical prostatectomy has undergone evolution in the last 100 years. Better understanding of the pelvic anatomy has led to a decrease in the blood loss during surgery and in the rate of urinary incontinence and erectile dysfunction following surgery. The introduction of laparoscopy in the late 1990s to this surgery provided the surgeon with a magnified multi-angle field of view and facilitated accurate dissection and suturing. Decreased damage to neighboring tissue made recovery hastier. Nevertheless, laparoscopic radical prostatectomy is a technically challenging surgery and did not become popular. The last step in the evolution of radical prostatectomy is the introduction of robotic systems for assistance in laparoscopic radical prostatectomy. A master-slave robotic system is composed of console and mechanical arms. The surgeon is provided with a magnified three dimensional view of the operative field and with two mechanical arms that accurately replicate its fingers movements. The initial results of robotic-assisted laparoscopic prostatectomy seem promising, however, long-term follow-up and comparison to open surgeries are lacking. Robotic systems were rapidly implemented in the American market and in the year 2006, 40% of all radical prostatectomies were robotic assisted. Future systems may reveal deep structures to the visualized surface by superimposing MRI images on the surgical field.

  9. The Royal Aircraft Establishment - 100 Years of Research.

    Science.gov (United States)

    1981-10-02

    OF RESIARCH.(U) OCT 61 A J SMITH UNCLASSIFIED RAE-TN-FS-432 DRIC-BR-80894 NLslomommmmoimco IE-E,,.IuENE 1111U1IIIjj -. ’ jI2 MICROCOPY RESOLUTION TESI ...Aircraft Estpblishment - 100 years of research 7a. (For Translations ) .Title in Foreign Language 7b. (For Conference Papers) Title, Place and Date of

  10. A 100-year review: Carbohydrates - characterization, digestion, and utilization

    Science.gov (United States)

    Our knowledge of the role of carbohydrates in dairy cattle nutrition has advanced substantially during the 100 years in which the Journal of Dairy Science has been published. In this review, we traced the history of scientific investigation and discovery from crude fiber, nitrogen-free extract, and ...

  11. Spring wheat gliadins: Have they changed in 100 years?

    Science.gov (United States)

    There have been many hard red spring (HRS) wheat cultivars released in North Dakota during the last 100 years. These cultivars have been improved for various characteristics such as, adaptation to weather conditions, high yield, and good milling and baking quality. The objectives of this study wer...

  12. Flood-hazard study: 100-year flood stage for Lucerne Lake, San Bernadino County, California

    Science.gov (United States)

    Busby, Mark William

    1977-01-01

    A study of the flood hydrology of Lucerne Valley, Calif., was made to develop the 100-year stage for Lucerne Lake. Synthetic-hydrologic techniques were used; and the 100-year flood stage was estimated to be at an elevation of 2,849.3 feet above mean sea level. Channel dimensions were measured at 59 sites in Lucerne Valley. Dranage area-discharge relations developed from channel-geometry data for sites nearby were used to estimate the discharge at 12 additional sites where channel geometry could not be measured. In order to compute the total volume discharge into the playa, the peak discharges were converted to volumes. From the Apple Valley report (Busby, 1975) the equation formulated from the relation between peak discharge and flood volume for the deserts of California was used to compute the flood volumes for routing into Lucerne Lake. (Woodard-USGS)

  13. Bacteriophages, revitalized after 100 years in the shadow of antibiotics

    Institute of Scientific and Technical Information of China (English)

    Hongping; Wei

    2015-01-01

    <正>The year 2015 marks 100 years since Dr.Frederick Twort discovered the"filterable lytic factor",which was later independently discovered and named "bacteriophage" by Dr.Felix d’Herelle.On this memorable centennial,it is exciting to see a special issue published by Virologica Sinica on Phages and Therapy.In this issue,readers will not only fi nd that bacteriophage research is a

  14. Extending dry storage of spent LWR fuel for 100 years.

    Energy Technology Data Exchange (ETDEWEB)

    Einziger, R. E.

    1998-12-16

    Because of delays in closing the back end of the fuel cycle in the U.S., there is a need to extend dry inert storage of spent fuel beyond its originally anticipated 20-year duration. Many of the methodologies developed to support initial licensing for 20-year storage should be able to support the longer storage periods envisioned. This paper evaluates the applicability of existing information and methodologies to support dry storage up to 100 years. The thrust of the analysis is the potential behavior of the spent fuel. In the USA, the criteria for dry storage of LWR spent fuel are delineated in 10 CFR 72 [1]. The criteria fall into four general categories: maintain subcriticality, prevent the release of radioactive material above acceptable limits, ensure that radiation rates and doses do not exceed acceptable levels, and maintain retrievability of the stored radioactive material. These criteria need to be considered for normal, off-normal, and postulated accident conditions. The initial safety analysis report submitted for licensing evaluated the fuel's ability to meet the requirements for 20 years. It is not the intent to repeat these calculations, but to look at expected behavior over the additional 80 years, during which the temperatures and radiation fields are lower. During the first 20 years, the properties of the components may change because of elevated temperatures, presence of moisture, effects of radiation, etc. During normal storage in an inert atmosphere, there is potential for the cladding mechanical properties to change due to annealing or interaction with cask materials. The emissivity of the cladding could also change due to storage conditions. If there is air leakage into the cask, additional degradation could occur through oxidation in breached rods, which could lead to additional fission gas release and enlargement of cladding breaches. Air in-leakage could also affect cover gas conductivity, cladding oxidation, emissivity changes, and

  15. 100 years after Smoluchowski: stochastic processes in cell biology

    Science.gov (United States)

    Holcman, D.; Schuss, Z.

    2017-03-01

    100 years after Smoluchowski introduced his approach to stochastic processes, they are now at the basis of mathematical and physical modeling in cellular biology: they are used for example to analyse and to extract features from a large number (tens of thousands) of single molecular trajectories or to study the diffusive motion of molecules, proteins or receptors. Stochastic modeling is a new step in large data analysis that serves extracting cell biology concepts. We review here Smoluchowski’s approach to stochastic processes and provide several applications for coarse-graining diffusion, studying polymer models for understanding nuclear organization and finally, we discuss the stochastic jump dynamics of telomeres across cell division and stochastic gene regulation.

  16. Opening the 100-Year Window for Time Domain Astronomy

    CERN Document Server

    Grindlay, Jonathan; Los, Edward; Servillat, Mathieu

    2012-01-01

    The large-scale surveys such as PTF, CRTS and Pan-STARRS-1 that have emerged within the past 5 years or so employ digital databases and modern analysis tools to accentuate research into Time Domain Astronomy (TDA). Preparations are underway for LSST which, in another 6 years, will usher in the second decade of modern TDA. By that time the Digital Access to a Sky Century @ Harvard (DASCH) project will have made available to the community the full sky Historical TDA database and digitized images for a century (1890--1990) of coverage. We describe the current DASCH development and some initial results, and outline plans for the "production scanning" phase and data distribution which is to begin in 2012. That will open a 100-year window into temporal astrophysics, revealing rare transients and (especially) astrophysical phenomena that vary on time-scales of a decade. It will also provide context and archival comparisons for the deeper modern surveys

  17. Total Hip Arthroplasty – over 100 years of operative history

    Directory of Open Access Journals (Sweden)

    Stephen Richard Knight

    2011-11-01

    Full Text Available Total hip arthroplasty (THA has completely revolutionised the nature in which the arthritic hip is treated, and is considered to be one of the most successful orthopaedic interventions of its generation (1. With over 100 years of operative history, this review examines the progression of the operation from its origins, together with highlighting the materials and techniques that have contributed to its development. Knowledge of its history contributes to a greater understanding of THA, such as the reasons behind selection of prosthetic materials in certain patient groups, while demonstrating the importance of critically analyzing research to continually determine best operative practice. Finally, we describe current areas of research being undertaken to further advance techniques and improve outcomes.

  18. Relativity and Gravitation : 100 Years After Einstein in Prague

    CERN Document Server

    Ledvinka, Tomáš; General Relativity, Cosmology and Astrophysics : Perspectives 100 Years After Einstein's Stay in Prague

    2014-01-01

    In early April 1911 Albert Einstein arrived in Prague to become full professor of theoretical physics at the German part of Charles University. It was there, for the first time, that he concentrated primarily on the problem of gravitation. Before he left Prague in July 1912 he had submitted the paper “Relativität und Gravitation: Erwiderung auf eine Bemerkung von M. Abraham” in which he remarkably anticipated what a future theory of gravity should look like. At the occasion of the Einstein-in-Prague centenary an international meeting was organized under a title inspired by Einstein's last paper from the Prague period: "Relativity and Gravitation, 100 Years after Einstein in Prague". The main topics of the conference included: classical relativity, numerical relativity, relativistic astrophysics and cosmology, quantum gravity, experimental aspects of gravitation, and conceptual and historical issues. The conference attracted over 200 scientists from 31 countries, among them a number of leading experts in ...

  19. Hypothetical constructs, hypothetical questions, and the expert witness.

    Science.gov (United States)

    Brodsky, Stanley L; Titcomb, Caroline; Sams, David M; Dickson, Kara; Benda, Yves

    2012-01-01

    Professor John Henry Wigmore in 1940 described the hypothetical question as an intolerable obstruction of truth. Since that time, the nature and application of the hypothetical question in the courtroom, as well as responses to this line of questioning during expert testimony, have been sources of controversy. Governed by legal philosophical foundations, the hypothetical construct addresses what there is, in a general sense, and what can or ought to be. Alexy (2004) has described the nature of legal philosophy as the epistemological question of what we can know. This article begins by examining the philosophical underpinnings, legal parameters, and teaching purposes of posing hypothetical queries. A social-psychological backdrop for the use of hypothetical questions is then discussed followed by a broader discussion of the hypothetical question's role in court procedures. This paper identifies hypothetical questions used in court as devices to elicit information, or as predictions that potentially change underlying factual interpretations of evidence. In particular, on cross examination hypothetical questions seek to make opposing experts assume facts that are incongruent with their conclusions or opinions. Sometimes in these situations, experts are led to re-evaluate opinions based on alternative understandings of events and behaviors. Thus, this paper's final aim is to explore a foundational understanding of hypothetical questions asked of expert witnesses with special reference to mental health issues. Options for responding to hypothetical questions on the stand are considered along the dimensions of assertiveness-passivity, compliance-resistance, and possible redefinitions of the hypothetical issues.

  20. Overuse syndrome in musicians--100 years ago. An historical review.

    Science.gov (United States)

    Fry, H J

    Overuse syndrome in musicians was extensively reported 100 years ago. The clinical features and results of treatment, which were recorded in considerable detail, match well the condition that is described today. The medical literature that is reviewed here extends from 1830 to 1911 and includes 21 books and 54 articles from the English language literature, apart from two exceptions; however, the writers of the day themselves reviewed French, German and Italian literature on the subject. The disorder was said to result from the overuse of the affected parts. Two theories of aetiology, not necessarily mutually exclusive, were argued. The central theory regarded the lesion as being in the central nervous system, the peripheral theory implied a primary muscle disorder. No serious case was put forward for a psychogenic origin, though emotional factors were believed to aggravate the condition. Advances in musical instrument manufacture--particularly the development of the concert piano and the clarinet--may have played a part in the prevalence of overuse syndrome in musicians. Total rest from the mechanical use of the hand was the only effective treatment recorded.

  1. [Sheehan's syndrome--a forgotten disease with 100 years' history].

    Science.gov (United States)

    Krysiak, Robert; Okopień, Bogusław

    2015-01-01

    Although named after Harold Sheehan, postpartum ischemic pituitary necrosis was reported for the first time 100 years ago in Przeglad Lekarski by Leon Konrad Gliński. In the majority of cases, the syndrome is a consequence of severe postpartum bleeding episode resulting in severe hypotension or hemorrhagic shock. The frequency of Sheehan's syndrome has decreased in developed countries as a result of improved obstetrical care, but this clinical entity remains a common cause of hypopituitarism in developing countries. The syndrome is characterized by varying degrees of anterior pituitary dysfunction resulting from the deficiency of multiple pituitary hormones. The order of frequency of hormone loss has generally been found to be growth hormone and prolactin, gonadotropins, ACTH and thyrotropin. Women with Sheehan's syndrome exhibit a variety of signs and symptoms including failure to lactate or resume menses, loss of genital and axillary hair, and often occurring long after delivery clinical manifestations of central hypothyroidism and secondary adrenal insufficiency. Diagnosis is based on laboratory studies, including hormone levels and hormone stimulation tests. Treatment of Sheehan's syndrome involves hormone replacement therapy. The aim of this study is to review current knowledge on clinically relevant aspects of this clinical entity and to provide the reader with recommendations concerning its diagnosis and treatment.

  2. Framing 100-year overflowing and overtopping marine submersion hazard resulting from the propagation of 100-year joint hydrodynamic conditions

    Science.gov (United States)

    Nicolae Lerma, A.; Bulteau, T.; Elineau, S.; Paris, F.; Pedreros, R.

    2016-12-01

    Marine submersion is an increasing concern for coastal cities as urban development reinforces their vulnerabilities while climate change is likely to foster the frequency and magnitude of submersions. Characterising the coastal flooding hazard is therefore of paramount importance to ensure the security of people living in such places and for coastal planning. A hazard is commonly defined as an adverse phenomenon, often represented by a magnitude of a variable of interest (e.g. flooded area), hereafter called response variable, associated with a probability of exceedance or, alternatively, a return period. Characterising the coastal flooding hazard consists in finding the correspondence between the magnitude and the return period. The difficulty lies in the fact that the assessment is usually performed using physical numerical models taking as inputs scenarios composed by multiple forcing conditions that are most of the time interdependent. Indeed, a time series of the response variable is usually not available so we have to deal instead with time series of forcing variables (e.g. water level, waves). Thus, the problem is twofold: on the one hand, the definition of scenarios is a multivariate matter; on the other hand, it is tricky and approximate to associate the resulting response, being the output of the physical numerical model, to the return period defined for the scenarios. In this study, we illustrate the problem on the district of Leucate, located in the French Mediterranean coast. A multivariate extreme value analysis of waves and water levels is performed offshore using a conditional extreme model, then two different methods are used to define and select 100-year scenarios of forcing variables: one based on joint exceedance probability contours, a method classically used in coastal risks studies, the other based on environmental contours, which are commonly used in the field of structure design engineering. We show that these two methods enable one to

  3. Progress of Cometary Science in the Past 100 Years

    Science.gov (United States)

    Sekanina, Zdenek

    1999-01-01

    Enormous strides made by cometary science during the 20th century defy any meaningful comparison of its state 100 years ago and now. The great majority of the subfields enjoying much attention nowadays did not exist in the year 1900. Dramatic developments, especially in the past 30-50 years, have equally affected observational and theoretical studies of comets. The profound diversification of observing techniques has been documented by the ever widening limits on the electromagnetic spectrum covered. While the time around 1900 marked an early period of slow and painful experimentation with photographic methods in cometary studies, observations of comets from the x-ray region to the radio waves have by now become routine. Many of the new techniques, and all those involved with the wavelengths shorter than about 300 nm, were made possible by another major breakthrough of this century - observing from space. Experiments on dedicated Earth-orbiting satellites as well as several deep-space probes have provided fascinating new information on the nature and makeup of comets. In broader terms, much of the progress has been achieved thanks to fundamental discoveries and major advances in electronics, whose applications resulted in qualitatively new instruments (e.g. radiotelescopes) and sensors or detectors (e.g. CCD arrays). The most universal effect on the entire cometary science, from observing to data handling to quantitative interpretations, has been, as in any other branch of science, due to the introduction of electronic computers, with their processing capabilities not only unheard of, but literally unimaginable, in the age of classical desk calculators. As if all this should not be enough, the today's generations of comet scientists have, in addition, been blessed with nature's highly appreciated cooperation. Indeed, in the span of a dozen years, between 1985 and 1997, we were privileged to witness four remarkable cometary events: (i) a return of Halley

  4. Global change and water resources in the next 100 years

    Science.gov (United States)

    Larsen, Matthew C.; Hirsch, R.M.

    2010-01-01

    We are in the midst of a continental-scale, multi-year experiment in the United States, in which we have not defined our testable hypotheses or set the duration and scope of the experiment, which poses major water-resources challenges for the 21st century. What are we doing? We are expanding population at three times the national growth rate in our most water-scarce region, the southwestern United States, where water stress is already great and modeling predicts decreased streamflow by the middle of this century. We are expanding irrigated agriculture from the west into the east, particularly to the southeastern states, where increased competition for ground and surface water has urban, agricultural, and environmental interests at odds, and increasingly, in court. We are expanding our consumption of pharmaceutical and personal care products to historic high levels and disposing them in surface and groundwater, through sewage treatment plants and individual septic systems. These substances are now detectable at very low concentrations and we have documented significant effects on aquatic species, particularly on fish reproduction function. We don’t yet know what effects on human health may emerge, nor do we know if we need to make large investments in water treatment systems, which were not designed to remove these substances. These are a few examples of our national-scale experiment. In addition to these water resources challenges, over which we have some control, climate change models indicate that precipitation and streamflow patterns will change in coming decades, with western mid-latitude North America generally drier. We have already documented trends in more rain and less snow in western mountains. This has large implications for water supply and storage, and groundwater recharge. We have documented earlier snowmelt peak spring runoff in northeastern and northwestern States, and western montane regions. Peak runoff is now about two weeks earlier than it was

  5. Global change and water resources in the next 100 years

    Science.gov (United States)

    Larsen, M. C.; Hirsch, R. M.

    2010-03-01

    We are in the midst of a continental-scale, multi-year experiment in the United States, in which we have not defined our testable hypotheses or set the duration and scope of the experiment, which poses major water-resources challenges for the 21st century. What are we doing? We are expanding population at three times the national growth rate in our most water-scarce region, the southwestern United States, where water stress is already great and modeling predicts decreased streamflow by the middle of this century. We are expanding irrigated agriculture from the west into the east, particularly to the southeastern states, where increased competition for ground and surface water has urban, agricultural, and environmental interests at odds, and increasingly, in court. We are expanding our consumption of pharmaceutical and personal care products to historic high levels and disposing them in surface and groundwater, through sewage treatment plants and individual septic systems. These substances are now detectable at very low concentrations and we have documented significant effects on aquatic species, particularly on fish reproduction function. We don’t yet know what effects on human health may emerge, nor do we know if we need to make large investments in water treatment systems, which were not designed to remove these substances. These are a few examples of our national-scale experiment. In addition to these water resources challenges, over which we have some control, climate change models indicate that precipitation and streamflow patterns will change in coming decades, with western mid-latitude North America generally drier. We have already documented trends in more rain and less snow in western mountains. This has large implications for water supply and storage, and groundwater recharge. We have documented earlier snowmelt peak spring runoff in northeastern and northwestern States, and western montane regions. Peak runoff is now about two weeks earlier than it was

  6. 100-Year Floodplains, 100 year flood plain data, Published in 2006, 1:1200 (1in=100ft) scale, Washoe County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at 1:1200 (1in=100ft) scale, was produced all or in part from Field Survey/GPS information as of 2006. It is described...

  7. 100 Years Jubilee for the discovery of the enzymes in yeast

    DEFF Research Database (Denmark)

    Berg, Rolf W.

    1997-01-01

    The work by Prof. E. Buchner 100 years ago which led to the discovery of the enzymes in yeast for brewing beer is reviewed.......The work by Prof. E. Buchner 100 years ago which led to the discovery of the enzymes in yeast for brewing beer is reviewed....

  8. 100 Years Jubilee for the discovery of the enzymes in yeast

    DEFF Research Database (Denmark)

    Berg, Rolf W.

    1997-01-01

    The work by Prof. E. Buchner 100 years ago which led to the discovery of the enzymes in yeast for brewing beer is reviewed.......The work by Prof. E. Buchner 100 years ago which led to the discovery of the enzymes in yeast for brewing beer is reviewed....

  9. 100-Year Floodplains, Digitized FEMA flood maps, Published in unknown, Eureka County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, was produced all or in part from Hardcopy Maps information as of unknown. It is described as 'Digitized FEMA flood maps'. Data by...

  10. 100-Year Floodplains, Floodplain, Published in 2000, Smaller than 1:100000 scale, Taylor County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at Smaller than 1:100000 scale, was produced all or in part from Hardcopy Maps information as of 2000. It is described...

  11. 100-Year Floodplains, FEMA FIRM Mapping, Published in 2014, Not Applicable scale, GIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at Not Applicable scale, was produced all or in part from Other information as of 2014. It is described as 'FEMA FIRM...

  12. Base (100-year) flood elevations for selected sites in Marion County, Missouri

    Science.gov (United States)

    Southard, Rodney E.; Wilson, Gary L.

    1998-01-01

    The primary requirement for community participation in the National Flood Insurance Program is the adoption and enforcement of floodplain management requirements that minimize the potential for flood damages to new construction and avoid aggravating existing flooding conditions. This report provides base flood elevations (BFE) for a 100-year recurrence flood for use in the management and regulation of 14 flood-hazard areas designated by the Federal Emergency Management Agency as approximate Zone A areas in Marion County, Missouri. The one-dimensional surface-water flow model, HEC-RAS, was used to compute the base (100-year) flood elevations for the 14 Zone A sites. The 14 sites were located at U.S., State, or County road crossings and the base flood elevation was determined at the upstream side of each crossing. The base (100-year) flood elevations for BFE 1, 2, and 3 on the South Fork North River near Monroe City, Missouri, are 627.7, 579.2, and 545.9 feet above sea level. The base (100-year) flood elevations for BFE 4, 5, 6, and 7 on the main stem of the North River near or at Philadelphia and Palmyra, Missouri, are 560.5, 539.7, 504.2, and 494.4 feet above sea level. BFE 8 is located on Big Branch near Philadelphia, a tributary to the North River, and the base (100-year) flood elevation at this site is 530.5 feet above sea level. One site (BFE 9) is located on the South River near Monroe City, Missouri. The base (100-year) flood elevation at this site is 619.1 feet above sea level. Site BFE 10 is located on Bear Creek near Hannibal, Missouri, and the base (100-year) elevation is 565.5 feet above sea level. The four remaining sites (BFE 11, 12, 13, and 14) are located on the South Fabius River near Philadelphia and Palmyra, Missouri. The base (100-year) flood elevations for BFE 11, 12, 13, and 14 are 591.2, 578.4, 538.7, and 506.9 feet above sea level.

  13. Assessment Gaze, Refraction, and Blur: The Course of Achievement Testing in the Past 100 Years

    Science.gov (United States)

    Baker, Eva L.; Chung, Gregory K. W. K.; Cai, Li

    2016-01-01

    This chapter addresses assessment (testing) with an emphasis on the 100-year period since the American Education Research Association was formed. The authors start with definitions and explanations of contemporary tests. They then look backward into the 19th century to significant work by Horace Mann and Herbert Spencer, who engendered two…

  14. Blister rust in North America: What we have not learned in the past 100 years

    Science.gov (United States)

    Eugene P. Van Arsdel; Brian W. Geils

    2011-01-01

    Introduction of Cronartium ribicola (white pine blister rust) greatly motivated development of tree disease control and research in America. Although foresters and pathologists have learned much in the past 100 years, more remains to learn. The most important lesson is that fear of blister rust has reduced pine regeneration more than the disease itself. Based on six...

  15. 100 years of selection of sugar beet at the Ivanivska research-selection station.

    Directory of Open Access Journals (Sweden)

    А. С. Лейбович

    2009-10-01

    Full Text Available In given article the historical way of development of selection of sugar beet at the Ivanivska research-selection station is opened. For 100 years of selection work at station by scientific employees are created and introduced into manufacture over 20 grades of sugar beet.

  16. 100 years of mapping the Holocene Rhine-Meuse delta plain: combining research and teaching

    NARCIS (Netherlands)

    Cohen, K. M.; Stouthamer, E.; Hoek, W. Z.; Middelkoop, H.

    2012-01-01

    The history of modern soil, geomorphological and shallow geological mapping in the Holocene Rhine-Meuse delta plain goes back about 100 years. The delta plain is of very heterogeneous build up, with clayey and peaty flood basins, dissected by sandy fluvial distributary channel belts with fine textur

  17. The Observation Of Defects Of School Buildings Over 100 Years Old In Perak

    Directory of Open Access Journals (Sweden)

    Alauddin Kartina

    2016-01-01

    Full Text Available Malaysia is blessed with a rich legacy of heritage buildings with unique architectural and historical values. The heritage buildings become a symbol of the national identity of our country. Therefore, heritage buildings, as important monuments should be conserved well to ensure the extension of the building’s life span and to make sure continuity functions of the building for future generations. The aim of this study is to analyze the types of defects attached in school buildings over 100 years located in Perak. The data were collected in four different schools aged over 100 years in Perak. The finding of the study highlighted the types of defects which were categorized based on building elements, including external wall, roof, door, ceiling, staircase, column, internal wall, floor and windows. Finding showed that the type of defects occurred in school buildings over 100 years in Perak is the same as the other heritage buildings. This finding can be used by all parties to take serious actions in preventing defects from occurring in buildings over 100 years. This would ensure that buildings’ functional life span can be extended for future use.

  18. Molecules at surfaces: 100 years of physical chemistry in Berlin-Dahlem.

    Science.gov (United States)

    Ertl, Gerhard

    2013-01-02

    Scratching the surface: for over 100 years the interactions of molecules at surfaces have been studied at the Fritz Haber Institute of the Max Planck Society, Berlin. Nobel Laureate Gerhard Ertl looks back at some of the key developments in this time, and the people who made them. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Assessing Hypothetical Gravity Control Propulsion

    CERN Document Server

    Millis, M G

    2006-01-01

    Gauging the benefits of hypothetical gravity control propulsion is difficult, but addressable. The major challenge is that such breakthroughs are still only notional concepts rather than being specific methods from which performance can be rigorously quantified. A recent assessment by Tajmar and Bertolami used the rocket equation to correct naive misconceptions, but a more fundamental analysis requires the use of energy as the basis for comparison. The energy of a rocket is compared to an idealized space drive for the following cases: Earth-to-orbit, interstellar transit, and levitation. The space drive uses 3.6 times less energy for Earth to orbit. For deep space travel, space drive energy scales as the square of delta-v, while rocket energy scales exponentially. This has the effect of rendering a space drive 150-orders-of-magnitude better than a 17,000-sec Specific Impulse rocket for sending a modest 5000 kg probe to traverse 5 light-years in 50 years. Indefinite levitation, which is impossible for a rocket...

  20. Creating Long Term Income Streams for the 100 Year Starship Study Initiative

    Science.gov (United States)

    Sylvester, A. J.

    Development and execution of long term research projects are very dependent on a consistent application of funding to maximize the potential for success. The business structure for the 100 Year Starship Study project should allow for multiple income streams to cover the expenses of the research objectives. The following examples illustrate the range of potential avenues: 1) affiliation with a charitable foundation for creating a donation program to fund a long term endowment for research, 2) application for grants to fund initial research projects and establish the core expertise of the research entity, 3) development of intellectual property which can then be licensed for additional revenue, 4) creation of spinout companies with equity positions retained by the lab for funding the endowment, and 5) funded research which is dual use for the technology goals of the interstellar flight research objectives. With the establishment of a diversified stream of funding options, then the endowment can be funded at a level to permit dedicated research on the interstellar flight topics. This paper will focus on the strategy of creating spinout companies to create income streams which would fund the endowment of the 100 Year Starship Study effort. This technique is widely used by universities seeking to commercially develop and market technologies developed by university researchers. An approach will be outlined for applying this technique to potentially marketable technologies generated as a part of the 100 Year Starship Study effort.

  1. 100 years of Epilepsia: landmark papers and their influence in neuropsychology and neuropsychiatry.

    Science.gov (United States)

    Hermann, Bruce

    2010-07-01

    As part of the 2009 International League Against Epilepsy (ILAE) Centenary Celebration, a special symposium was dedicated to Epilepsia (100 Years of Epilepsia: Landmark Papers and Their Influence). The Associate Editors were asked to identify a particularly salient and meaningful paper in their areas of expertise. From the content areas of neuropsychology and neuropsychiatry two very interesting papers were identified using quite different ascertainment techniques. One paper addressed the problem of psychosis in temporal lobe epilepsy, whereas the other represents the first paper to appear in Epilepsia presenting quantitative assessment of cognitive status in epilepsy. These two papers are reviewed in detail and placed in historical context.

  2. Accuracy assessment of the UT1 prediction method based on 100-year series analysis

    CERN Document Server

    Malkin, Z; Tolstikov, A

    2013-01-01

    A new method has been developed at the Siberian Research Institute of Metrology (SNIIM) for highly accurate prediction of UT1 and Pole coordinates. The method is based on construction of a general polyharmonic model of the variations of the Earth rotation parameters using all the data available for the last 80-100 years, and modified autoregression technique. In this presentation, a detailed comparison was made of real-time UT1 predictions computed making use of this method in 2006-2010 with simultaneous predictions computed at the International Earth Rotation and Reference Systems Service (IERS). Obtained results have shown that proposed method provides better accuracy at different prediction lengths.

  3. Fascia Research Congress evidence from the 100 year perspective of Andrew Taylor Still.

    Science.gov (United States)

    Findley, Thomas W; Shalwala, Mona

    2013-07-01

    More than 100 years ago A.T. Still MD founded osteopathic medicine, and specifically described fascia as a covering, with common origins of layers of the fascial system despite diverse names for individual parts. Fascia assists gliding and fluid flow and is highly innervated. Fascia is intimately involved with respiration and with nourishment of all cells of the body, including those of disease and cancer. This paper reviews information presented at the first three International Fascia Research Congresses in 2007, 2009 and 2012 from the perspective of Dr Still, that fascia is vital for organism's growth and support, and it is where disease is sown. Published by Elsevier Ltd.

  4. 100-year history of the development of bread winter wheat breeding programs

    Directory of Open Access Journals (Sweden)

    М. А. Литвиненко

    2016-05-01

    Full Text Available Purpose. Review of the main achievements of the Wheat Breeding and Seed ProductionDepartment in the Plant Breeding and Genetic Institute – National Centre of Seed and Cultivar Investigation in the developing theoretical principles of breeding and creation of winter wheat varieties of different types during 100-year (1916–2016 period of breeding programs realization. Results. The main theoretical, methodical developments and breeding achievements of Wheat Breeding and Seed Production Department during 100-year (1916–2016 history have been considered. In the course of the Department activity, the research and metho­dology grounds of bread winter wheat breeding and seed production have been laid, 9 stages of breeding programs development have been accomplished. As a result, more than 130 varieties of different types have been created, 87 of them have been released in some periods or registered in the State registers of plants varieties of Ukraine and other countries and grown in the total sowing area about 220 million hectares.

  5. Solving the Supreme Problem: 100 years of selection and recruitment at the Journal of Applied Psychology.

    Science.gov (United States)

    Ployhart, Robert E; Schmitt, Neal; Tippins, Nancy T

    2017-03-01

    This article reviews 100 years of research on recruitment and selection published in the Journal of Applied Psychology. Recruitment and selection research has been present in the Journal from the very first issue, where Hall (1917) suggested that the challenge of recruitment and selection was the Supreme Problem facing the field of applied psychology. As this article shows, the various topics related to recruitment and selection have ebbed and flowed over the years in response to business, legal, and societal changes, but this Supreme Problem has captivated the attention of scientist-practitioners for a century. Our review starts by identifying the practical challenges and macro forces that shaped the sciences of recruitment and selection and helped to define the research questions the field has addressed. We then describe the evolution of recruitment and selection research and the ways the resulting scientific advancements have contributed to staffing practices. We conclude with speculations on how recruitment and selection research may proceed in the future. Supplemental material posted online provides additional depth by including a summary of practice challenges and scientific advancements that affected the direction of selection and recruitment research and an outline of seminal articles published in the Journal and corresponding time line. The 100-year anniversary of the Journal of Applied Psychology is very much the celebration of recruitment and selection research, although predictions about the future suggest there is still much exciting work to be done. (PsycINFO Database Record

  6. Oceanic environmental changes of subarctic Bering Sea in recent 100 years: Evidence from molecular fossils

    Institute of Scientific and Technical Information of China (English)

    LU; Bing; CHEN; Ronghua; ZHOU; Huaiyang; WANG; Zipan; CHEN

    2005-01-01

    The core sample B2-9 from the seafloor of the subarctic Bering Sea was dated with 210Pb to obtain a consecutive sequence of oceanic sedimentary environments at an interval of a decade during 1890-1999. A variety of molecular fossils were detected, including n-alkanes, isoprenoids, fatty acids, sterols, etc. By the characteristics of these fine molecules (C27, C28, and C29 sterols) and their molecular indices (Pr/Ph, ∑C+22/∑C?21, CPI and C18∶2/C18∶0) and in consideration of the variation of organic carbon content, the 100-year evolution history of subarctic sea paleoenvironment was reestablished. It is indicated that during the past 100 years in the Arctic, there were two events of strong climate warming (1920-1950 and 1980-1999), which resulted in an oxidated sediment environment owing to decreasing terrigenous organic matters and increasing marine-derived organic matters, and two events of transitory climate cooling (1910 and 1970-1980), which resulted in a slightly reduced sediment environment owing to increasing terrigenous organic matters and decreasing marine-derived organic matters. It is revealed that the processes of warming/cooling alternated climate are directly related to the Arctic and global climate variations.

  7. Did Open Solar Magnetic Field Increase during the Last 100 Years: A Reanalysis of Geomagnetic Activity

    CERN Document Server

    Mursula, K; Karinen, A

    2004-01-01

    Long-term geomagnetic activity presented by the aa index has been used to show that the heliospheric magnetic field has more than doubled during the last 100 years. However, serious concern has been raised on the long-term consistency of the aa index and on the centennial rise of the solar magnetic field. Here we reanalyze geomagnetic activity during the last 100 years by calculating the recently suggested IHV (Inter-Hour Variability) index as a measure of local geomagnetic activity for seven stations. We find that local geomagnetic activity at all stations follows the same qualitative long-term pattern: an increase from early 1900s to 1960, a dramatic dropout in 1960s and a (mostly weaker) increase thereafter. Moreover, at all stations, the activity at the end of the 20th century has a higher average level than at the beginning of the century. This agrees with the result based on the aa index that global geomagnetic activity, and thereby, the open solar magnetic field has indeed increased during the last 100...

  8. Reducing hypothetical bias in choice experiments

    DEFF Research Database (Denmark)

    Ladenburg, Jacob; Olsen, Søren Bøye; Nielsen, Rasmus Christian Fejer

    Hypothetical bias in stated preference studies is an essential problem which reduces the validity of the obtained welfare estimates for non-market goods. In the attempt to mitigate hypothetical bias, a type of reminder known as Cheap Talk, has been applied in previous studies and found to overall...... eliminate some of the hypothetical bias. The present paper tests an addition to Cheap Talk, an Opt-Out Reminder. The Opt-Out Reminder is an objective short script presented prior to the choice sets, prompting the respondent to choose the opt-out alternative, if he/she finds the proposed policy generated...... alternatives in a choice set too expensive. The results suggest that adding an Opt-Out Reminder to Cheap Talk can in fact reduce hypothetical bias even further and reduces some of the ineffectiveness of CT in relation to the survey bid range and experienced respondents....

  9. Sedimentary records of eutrophication and hypoxia in the Changjiang Estuary over the last 100 years

    Science.gov (United States)

    Xuwen, F.; Hongliang, L.; Zhao, M.; Xuefa, S.

    2012-12-01

    We selected two cores in the Changjiang Estuary, one located in the Changjiang Estuary mud area (CEMA) within the region of seasonal hypoxia, the other located in the Cheju Island mud area (SCIMA) and outside the hypoxia region. The grain size, total organic carbon (TOC), stable carbon isotopic ratios (δ13 Corg), biomarkers (the sum of brassicasterol, dinosterol and alkenone) and some redox sensitive elements (RSEs) were determined on the 210Pb-dated sediment cores to study potential hundrend-years eutrophication and hypoxia. The sediment record in CEMA showed that an increase in TOC (21%), biomarkers (141%) and δ13 Corg (1.6‰PDB ) occurred since 1950s and a marked increase since 1970s. These distributions indicated the enhanced productivity and establshed the history of eutrophication in the Changjiang Estuary during the past 100 years. Some RSEs have been enriched significantly since the late 1960s to 1970s, the rates of Mo/Al, Cd/Al and As/Al increased about 83%, 73% and 50% respectively. These data may indicate the onset of hypoxia in the Changjiang Estuary during the last 100 years. The increasing of marine organic matter and RSEs accumulation was corresponding with the fertilizer consumption and high nutrient inputs from the Changjiang River. The riverine runoff of fertilizers and nutrients stimulated the algae (e g. brassicasterol, dinosterol) blooming. Enhanced primary production resulted in an enrichment of organic matter and hypoxia invoked organic matter preserved in the sediment. For the core sediment in SCIMA, the geochemical indicators (TOC, biomarkers and δ13Corg ) increased in difference degrees before 1950s~1970s and then were almost the constant. Productivity in the SCIMA have been mainly influenced by climate ocean circulation changes over the last 100 years. The RSEs were controlled by "grain size effects" which indicated no hypoxia occurred. This study concluded that δ13 Corg, RSEs and biomarkers in sediment could be used to trace or

  10. Operation of the aircraft as a discipline of knowledge after 100 years of experience

    Directory of Open Access Journals (Sweden)

    Stanisław Danilecki

    2015-12-01

    Full Text Available The paper presents the course of the most important stages of development of the discipline related to the maintenance of aircrafts, as a synthesis of the 100-year experience. It is presented linking of technical maintenance of the aircraft with other disciplines of knowledge. The scope of technical maintenance was defined. The division and analysis of the methods for the maintenance was made. There were defined and discussed definitions used in the theory of maintenance, in conjunction with the construction of the aircraft and the tasks arising for constructor-manufacturer. MSG subsequent versions of the document constituting the logistical procedures for determining the programmable handling of civil airplanes were discussed.[b]Keywords[/b]: aviation, aircraft, maintenance aircrafts

  11. 100 years of applied psychology research on individual careers: From career management to retirement.

    Science.gov (United States)

    Wang, Mo; Wanberg, Connie R

    2017-03-01

    This article surveys 100 years of research on career management and retirement, with a primary focus on work published in the Journal of Applied Psychology. Research on career management took off in the 1920s, with most attention devoted to the development and validation of career interest inventories. Over time, research expanded to attend to broader issues such as the predictors and outcomes of career interests and choice; the nature of career success and who achieves it; career transitions and adaptability to change; retirement decision making and adjustment; and bridge employment. In this article, we provide a timeline for the evolution of the career management and retirement literature, review major theoretical perspectives and findings on career management and retirement, and discuss important future research directions. (PsycINFO Database Record

  12. Sustainable Foods and Medicines Support Vitality, Sex and Longevity for a 100-Year Starship Expedition

    Science.gov (United States)

    Edwards, M. R.

    Extended space flight requires foods and medicines that sustain crew health and vitality. The health and therapeutic needs for the entire crew and their children for a 100-year space flight must be sustainable. The starship cannot depend on resupply or carry a large cargo of pharmaceuticals. Everything in the starship must be completely recyclable and reconstructable, including food, feed, textiles, building materials, pharmaceuticals, vaccines, and medicines. Smart microfarms will produce functional foods with superior nutrition and sensory attributes. These foods provide high-quality protein and nutralence (nutrient density), that avoids obesity, diabetes, and other Western diseases. The combination of functional foods, lifestyle actions, and medicines will support crew immunity, energy, vitality, sustained strong health, and longevity. Smart microfarms enable the production of fresh medicines in hours or days, eliminating the need for a large dispensary, which eliminates concern over drug shelf life. Smart microfarms are adaptable to the extreme growing area, resource, and environmental constraints associated with an extended starship expedition.

  13. [The 100-year anniversary of Eugene Jamot's (1879-1937) admittance to the Pharo School].

    Science.gov (United States)

    Milleliri, J M; Louis, F J

    2010-04-01

    For the 100-year anniversary of Dr. Eugene Jamot's (1879-1937) admittance to the Pharo School (then known as the Training School of the Colonial Army Health Corps), the authors describe the life of a French military physician working in Africa. Eugene Jamot devoted 22 years of his life to fighting sleeping sickness. Using a standardized approach that has become a textbook example, he was highly successful in controlling this dreaded tropical disease. Despite being criticized by some officials of the colonial administration and becoming the target of an obvious smear campaign because of his strong personality and growing fame, Jamot handed down a set of values that are recognized by most physicians working to improve the living conditions of the unfortunately still suffering African population.

  14. Prediction of Climatic Change for the Next 100 Years in the Apulia Region, Southern Italy

    Directory of Open Access Journals (Sweden)

    Mladen Todorovic

    2007-12-01

    Full Text Available The impact of climate change on water resources and use for agricultural production has become a critical question for sustainability. Our objective was investigate the impact of the expected climate changes for the next 100 years on the water balance variations, climatic classifications, and crop water requirements in the Apulia region (Southern Italy. The results indicated that an increase of temperature, in the range between 1.3 and 2,5 °C, is expected in the next 100 years. The reference evapotranspiration (ETo variations would follow a similar trend; as averaged over the whole region, the ETo increase would be about 15.4%. The precipitation will not change significantly on yearly basis although a slight decrease in summer months and a slight increase during the winter season are foreseen. The climatic water deficit (CWD is largely caused by ETo increase, and it would increase over the whole Apulia region in average for more than 200 mm. According to Thornthwaite and Mather climate classification, the moisture index will decrease in the future, with decreasing of humid areas and increasing of aridity zones. The net irrigation requirements (NIR, calculated for ten major crops in the Apulia region, would increase significantly in the future. By the end of the 21st Century, the foreseen increase of NIR, in respect to actual situation, is the greatest for olive tree (65%, wheat (61%, grapevine (49%, and citrus (48% and it is slightly lower for maize (35%, sorghum (34%, sunflower (33%, tomato (31%, and winter and spring sugar beet (both 27%.

  15. 77 FR 66823 - Freedom of Information Act Request for Papers Submitted to DARPA for the 2011 100 Year Starship...

    Science.gov (United States)

    2012-11-07

    ... of the Secretary Freedom of Information Act Request for Papers Submitted to DARPA for the 2011 100 Year Starship Symposium AGENCY: Defense Advanced Research Projects Agency (DARPA), DoD. ACTION: Notice... panels at the 2011 100 Year Starship Symposium must provide DARPA a written response explaining...

  16. Reducing hypothetical bias in choice experiments

    DEFF Research Database (Denmark)

    Ladenburg, Jacob; Olsen, Søren Bøye; Nielsen, Rasmus Christian Fejer

    eliminate some of the hypothetical bias. The present paper tests an addition to Cheap Talk, an Opt-Out Reminder. The Opt-Out Reminder is an objective short script presented prior to the choice sets, prompting the respondent to choose the opt-out alternative, if he/she finds the proposed policy generated...... alternatives in a choice set too expensive. The results suggest that adding an Opt-Out Reminder to Cheap Talk can in fact reduce hypothetical bias even further and reduces some of the ineffectiveness of CT in relation to the survey bid range and experienced respondents....

  17. [Nutrient dynamics over the past 100 years and its restoration baseline in Dianshan Lake].

    Science.gov (United States)

    Li, Xiao-Ping; Chen, Xiao-Hua; Dong, Xu-Hui; Dong, Zhi; Sun, Dun-Ping

    2012-10-01

    The restoration of eutrophic lakes requires a good knowledge on the history and baseline of nutrients in the lakes. This work conducted an analysis on 210Pb/137Cs, water content, loss-on-ignition, sedimentary total phosphorus (TP), total nitrogen (TN), total organic carbon (TOC) and diatoms in the four sediment cores from Dianshan Lake (near Shanghai City). Good coherence in palaeoproxies between the cores indicates a relatively stable sedimentary environment. With increasing human impact, diatom communities shifted from oligo-trophic species Cyclotella bodanica, C. ocelata, Achnanthes minutissima, Cocconeis placentula var lineate, Cymbella sp. , Fragilaria pintata, F. brevistrata, F. construens var venter to recent eutrophic species including Cyclostephanos dubias, C. atomus, Stephanodiscus minitulus, S. hantzschi, Aulacoseria alpigena. The epilimnetic TP over the past 100 years reconstructed using an established diatom-TP transfer function matches well with the monitoring TP where exists. Based on the sedimentary nutrient characteristics and diatom-reconstructed nutrient dynamics, we proposed that the nutrient baseline for Dianshan Lake is 50-60 microg x L(-1), 500 mg x kg(-1) and 550 mg x kg(-1) for water TP concentration, sedimentary TP and TN, respectively.

  18. Individual differences and their measurement: A review of 100 years of research.

    Science.gov (United States)

    Sackett, Paul R; Lievens, Filip; Van Iddekinge, Chad H; Kuncel, Nathan R

    2017-03-01

    This article reviews 100 years of research on individual differences and their measurement, with a focus on research published in the Journal of Applied Psychology. We focus on 3 major individual differences domains: (a) knowledge, skill, and ability, including both the cognitive and physical domains; (b) personality, including integrity, emotional intelligence, stable motivational attributes (e.g., achievement motivation, core self-evaluations), and creativity; and (c) vocational interests. For each domain, we describe the evolution of the domain across the years and highlight major theoretical, empirical, and methodological developments, including relationships between individual differences and variables such as job performance, job satisfaction, and career development. We conclude by discussing future directions for individual differences research. Trends in the literature include a growing focus on substantive issues rather than on the measurement of individual differences, a differentiation between constructs and measurement methods, and the use of innovative ways of assessing individual differences, such as simulations, other-reports, and implicit measures. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  19. The Current Status of Ticks in Turkey: A 100-Year Period Review from 1916 to 2016.

    Science.gov (United States)

    İnci, Abdullah; Yıldırım, Alparslan; Düzlü, Önder

    2016-09-01

    Environmental and bio-ecological changes, some administrative and political mistakes, and global warming seriously affect the behaviors of ticks in Turkey and globally. The global public sensitivity toward tick infestations has increased along with increases in tick-borne diseases (TBDs). Recently, the World Health Organization (WHO) developed a new political concept, "One Health," for specific struggle strategies against tick infestations and TBDs. To highlight the importance of the issue, the WHO had declared the year 2015 for vector-borne diseases and adopted the slogan "small bites big threat". In global struggle strategies, the epidemiological aspects and dynamics of increasing tick populations and their effects on the incidence of the TBDs mainly with zoonotic characteristics have been specifically targeted. In Turkey, during the last century, approximately 47 tick species, including eight soft and 39 hard tick species in three and six genera belonging to Argasidae and Ixodidae, respectively, had already been reported. In this article, the recorded tick species, regional infestations, and medical and veterinary importance in Turkey were chronologically reviewed based on a 100-year period between 1916 and 2016.

  20. Under Connecticut Skies: Exploring 100 Years of Astronomy at Van Vleck Observatory in Middletown, Connecticut

    Science.gov (United States)

    Kilgard, Roy E.; Williams, Amrys; Erickson, Paul; Herbst, William; Redfield, Seth

    2017-01-01

    Under Connecticut Skies examines the history of astronomy at Van Vleck Observatory, located on the campus of Wesleyan University in Middletown, Connecticut. Since its dedication in June of 1916, Van Vleck has been an important site of astronomical research, teaching, and public outreach. Over a thousand visitors pass through the observatory each year, and regular public observing nights happen year-round in cooperation with the Astronomical Society of Greater Hartford. Our project explores the place-based nature of astronomical research, the scientific instruments, labor, and individuals that have connected places around the world in networks of observation, and the broader history of how observational astronomy has linked local people, amateur observers, professional astronomers, and the tools and objects that have facilitated their work under Connecticut’s skies over the past 100 years. Our research team has produced a historical exhibition to help commemorate the observatory’s centennial that opened to the public in May of 2016. Our work included collecting, documenting, and interpretting this history through objects, archival documents, oral histories, photographs, and more. The result is both a museum and a working history "laboratory" for use by student and professional researchers. In addition to the exhibit itself, we have engaged in new interpretive programs to help bring the history of astronomy to life. Future work will include digitization of documents and teaching slides, further collection of oral histories, and expanding the collection to the web for use by off-site researches.

  1. Lessons to be learned from an analysis of ammonium nitrate disasters in the last 100 years

    Energy Technology Data Exchange (ETDEWEB)

    Pittman, William; Han, Zhe; Harding, Brian; Rosas, Camilo; Jiang, Jiaojun; Pineda, Alba; Mannan, M. Sam, E-mail: mannan@tamu.edu

    2014-09-15

    Highlights: • Root causes and contributing factors from ammonium nitrate incidents are categorized into 10 lessons. • The lessons learned from the past 100 years of ammonium nitrate incidents can be used to improve design, operation, and maintenance procedures. • Improving organizational memory to help improve safety performance. • Combating and changing organizational cultures. - Abstract: Process safety, as well as the safe storage and transportation of hazardous or reactive chemicals, has been a topic of increasing interest in the last few decades. The increased interest in improving the safety of operations has been driven largely by a series of recent catastrophes that have occurred in the United States and the rest of the world. A continuous review of past incidents and disasters to look for common causes and lessons is an essential component to any process safety and loss prevention program. While analyzing the causes of an accident cannot prevent that accident from occurring, learning from it can help to prevent future incidents. The objective of this article is to review a selection of major incidents involving ammonium nitrate in the last century to identify common causes and lessons that can be gleaned from these incidents in the hopes of preventing future disasters. Ammonium nitrate has been involved in dozens of major incidents in the last century, so a subset of major incidents were chosen for discussion for the sake of brevity. Twelve incidents are reviewed and ten lessons from these incidents are discussed.

  2. Physiological and morphological acclimation to height in cupressoid leaves of 100-year-old Chamaecyparis obtusa.

    Science.gov (United States)

    Shiraki, Ayumi; Azuma, Wakana; Kuroda, Keiko; Ishii, H Roaki

    2016-10-15

    Cupressoid (scale-like) leaves are morphologically and functionally intermediate between stems and leaves. While past studies on height acclimation of cupressoid leaves have focused on acclimation to the vertical light gradient, the relationship between morphology and hydraulic function remains unexplored. Here, we compared physiological and morphological characteristics between treetop and lower-crown leaves of 100-year-old Chamaecyparis obtusa Endl. trees (~27 m tall) to investigate whether height-acclimation compensates for hydraulic constraints. We found that physiological acclimation of leaves was determined by light, which drove the vertical gradient of evaporative demand, while leaf morphology and anatomy were determined by height. Compared with lower-crown leaves, treetop leaves were physiologically acclimated to water stress. Leaf hydraulic conductance was not affected by height, and this contributed to higher photosynthetic rates of treetop leaves. Treetop leaves had higher leaf area density and greater leaf mass per area, which increase light interception but could also decrease hydraulic efficiency. We inferred that transfusion tissue flanking the leaf vein, which was more developed in the treetop leaves, contributes to water-stress acclimation and maintenance of leaf hydraulic conductance by facilitating osmotic adjustment of leaf water potential and efficient water transport from xylem to mesophyll. Our findings may represent anatomical adaptation that compensates for hydraulic constraints on physiological function with increasing height.

  3. Revisiting extreme storms of the past 100 years for future safety of large water management infrastructures

    Science.gov (United States)

    Chen, Xiaodong; Hossain, Faisal

    2016-07-01

    Historical extreme storm events are widely used to make Probable Maximum Precipitation (PMP) estimates, which form the cornerstone of large water management infrastructure safety. Past studies suggest that extreme precipitation processes can be sensitive to land surface feedback and the planetary warming trend, which makes the future safety of large infrastructures questionable given the projected changes in land cover and temperature in the coming decades. In this study, a numerical modeling framework was employed to reconstruct 10 extreme storms over CONUS that occurred during the past 100 years, which are used by the engineering profession for PMP estimation for large infrastructures such as dams. Results show that the correlation in daily rainfall for such reconstruction can range between 0.4 and 0.7, while the correlation for maximum 3-day accumulation (a standard period used in infrastructure design) is always above 0.5 for post-1948 storms. This suggests that current numerical modeling and reanalysis data allow us to reconstruct big storms after 1948 with acceptable accuracy. For storms prior to 1948, however, reconstruction of storms shows inconsistency with observations. Our study indicates that numerical modeling and data may not have advanced to a sufficient level to understand how such old storms (pre-1948) may behave in future warming and land cover conditions. However, the infrastructure community can certainly rely on the use of model reconstructed extreme storms of the 1948-present period to reassess safety of our large water infrastructures under assumed changes in temperature and land cover.

  4. Reactions to Hypothetical, Jealousy Producing Events.

    Science.gov (United States)

    Hansen, Gary L.

    1982-01-01

    Asked subjects (N=220) how they would feel about their mates' behavior in eight hypothetical situations designed to measure jealousy. Responses indicated that jealousy is likely to be a major issue. Sex role orientation is most consistently related to jealousy with sex role traditional subjects being the most jealous. (Author)

  5. LOW FREQUENCY VARIABILITY OF INTERANNUAL CHANGE PATTERNS FOR GLOBAL MEAN TEMPERATURE DURING THE RECENT 100 YEARS

    Institute of Scientific and Technical Information of China (English)

    刘晶淼; 丁裕国; 等

    2002-01-01

    The TEEOF method that expands temporally is used to conduct a diagnostic study of the variation patterns of 1,3,6and 10 years with regard to mean air temperature over the globe and Southern and Northern Hemispheres over the course of 100 years.The results show that the first mode of TEEOF takes up more than 50%in the total variance,with each of the first mode in the interannual osicllations generally standing for annually varying patterns which are related with climate and reflecting long-term tendency of change in air temperature.It is particularly true for the first mode on the 10-year scale.which shows an obvious ascending ascending trend concerning the temperature in winter and consistently the primary component of time goes in a way that is very close to the sequence of actual temperature,Apart from the first mode of all time sections of TEEOF for the globe and the two hemispheres and the second mode of the 1-year TEEOF.interannual variation described by other characteristic vectors are showing various patterns,with corresponding primary components having relation with longterm variability of specific interannual quasi-periodic oscillation structures.A T2 test applied to the annual variation pattern shows that the abrupt changes for the southern Hemisphere and the globe come close to the result of a uni-element t test for mean temperature than those for the Northern Hemisphere do.It indicates that the T2 test,when carried out with patterns of multiple variables.Seems more reasonable than the t test with single elements.

  6. To Humbly Go: Guarding Against Perpetuating Models of Colonization in the 100-Year Starship Study

    Science.gov (United States)

    Kramer, W. R.

    Past patterns of exploration, colonization and exploitation on Earth continue to provide the predominant paradigms that guide many space programs. Any project of crewed space exploration, especially of the magnitude envisioned by the 100-Year Starship Study, must guard against the hubris that may emerge among planners, crew, and others associated with the project, including those industries and bureaucracies that will emerge from the effort. Maintaining a non-exploitative approach may be difficult in consideration of the century of preparatory research and development and the likely multigenerational nature of the voyage itself. Starting now with mission dreamers and planners, the purpose of the voyage must be cast as one of respectful learning and humble discovery, not of conquest (either actual or metaphorical) or other inappropriate models, including military. At a minimum, the Study must actively build non-violence into the voyaging culture it is beginning to create today. References to exploitive colonization, conquest, destiny and other terms from especially American frontier mythology, while tempting in their propagandizing power, should be avoided as they limit creative thinking about alternative possible futures. Future voyagers must strive to adapt to new environments wherever possible and be assimilated by new worlds both biologically and behaviorally rather than to rely on attempts to recreate the Earth they have left. Adaptation should be strongly considered over terraforming. This paper provides an overview of previous work linking the language of colonization to space programs and challenges the extension of the myth of the American frontier to the Starship Study. It argues that such metaphors would be counter-productive at best and have the potential to doom long-term success and survival by planting seeds of social decay and self-destruction. Cautions and recommendations are suggested.

  7. Rainfall and Drought In Equatorial East Africa During The Past 1,100 Years

    Science.gov (United States)

    Verschuren, D.; Laird, K. R.; Cumming, B. F.

    Knowledge of natural long-term rainfall variability is essential for water-resource and land-use management in all dry-land regions of the world. In tropical Africa, data rel- evant to determining this variability are scarce because of the lack of long instrumen- tal climate records and the limited potential of some high-resolution proxy climate archives such as tree rings and ice cores. An 1,100-year reconstruction of decadel- scale variability in African rainfall and drought based on lake-level and salinity fluc- tuations of Lake Naivasha (Eastern Rift Valley, Kenya) now indicates that eastern equatorial Africa within the last millennia has alternated between strongly contrast- ing climatic conditions, including significantly reduced effective moisture during the 'Medieval Warm Period' (~AD 900-1270), and a generally higher effective moisture than today during the 'Little Ice Age' (~AD 1270-1850) interrupted by three episodes of prolonged aridity (~AD 1380-1420, 1560-1620, and 1760-1840) more severe than any historically recorded drought. Pattern and timing of the reconstructed Little Ice Age climate fluctuations correlate with the residual record of atmospheric radiocar- bon production, suggesting that long-term variations in solar radiation may have con- tributed to African rainfall variability at these time scales. In agreement with other recently documented instances of a solar influence on long-term variations in hydro- logical balance, solar minima correlated with increases in effective moisture and solar maxima with increased aridity. It remains unclear, however, whether variation in solar radiation generated fluctuations in effective moisture mainly by means of a direct or indirect influence on rainfall, or rather through the influence of temperature variations on evaporation rates.

  8. The Archives of the Department of Terrestrial Magnetism: Documenting 100 Years of Carnegie Science

    Science.gov (United States)

    Hardy, S. J.

    2005-12-01

    The archives of the Department of Terrestrial Magnetism (DTM) of the Carnegie Institution of Washington document more than a century of geophysical and astronomical investigations. Primary source materials available for historical research include field and laboratory notebooks, equipment designs, plans for observatories and research vessels, scientists' correspondence, and thousands of expedition and instrument photographs. Yet despite its history, DTM long lacked a systematic approach to managing its documentary heritage. A preliminary records survey conducted in 2001 identified more than 1,000 linear feet of historically-valuable records languishing in dusty, poorly-accessible storerooms. Intellectual control at that time was minimal. With support from the National Historical Publications and Records Commission, the "Carnegie Legacy Project" was initiated in 2003 to preserve, organize, and facilitate access to DTM's archival records, as well as those of the Carnegie Institution's administrative headquarters and Geophysical Laboratory. Professional archivists were hired to process the 100-year backlog of records. Policies and procedures were established to ensure that all work conformed to national archival standards. Records were appraised, organized, and rehoused in acid-free containers, and finding aids were created for the project web site. Standardized descriptions of each collection were contributed to the WorldCat bibliographic database and the AIP International Catalog of Sources for History of Physics. Historic photographs and documents were digitized for online exhibitions to raise awareness of the archives among researchers and the general public. The success of the Legacy Project depended on collaboration between archivists, librarians, historians, data specialists, and scientists. This presentation will discuss key aspects (funding, staffing, preservation, access, outreach) of the Legacy Project and is aimed at personnel in observatories, research

  9. 100-Year Floodplains, flood plain, Published in 2009, 1:24000 (1in=2000ft) scale, Washington County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at 1:24000 (1in=2000ft) scale, was produced all or in part from Other information as of 2009. It is described as 'flood...

  10. The Hunterian Neurosurgical Laboratory: the first 100 years of neurosurgical research.

    Science.gov (United States)

    Sampath, P; Long, D M; Brem, H

    2000-01-01

    Modern neurosurgery has long had a strong laboratory foundation, and much of this tradition can be traced to the Hunterian Neurosurgical Laboratory of the Johns Hopkins Hospital. Founded with the basic goals of investigating the causes and symptoms of disease and establishing the crucial role that surgeons may play in the treatment of disease, the Hunterian laboratory has adhered to these tenets, despite the dramatic changes in neurosurgery that have occurred in the last 100 years. Named for the famous English surgeon John Hunter (1728-1793), the Hunterian laboratory was conceived by William Welch and William Halsted as a special laboratory for experimental work in surgery and pathology. In 1904, Harvey Cushing was appointed by Halsted to direct the laboratory. With the three primary goals of student education, veterinary surgery that stressed surgical techniques, and meticulous surgical and laboratory record-keeping, the laboratory was quite productive, introducing the use of physiological saline solutions, describing the anatomic features and function of the pituitary gland, and establishing the field of endocrinology. In addition, the original development of hanging drop tissue culture, fundamental investigations into cerebrospinal fluid, and countless contributions to otolaryngology by Samuel Crowe all occurred during this "crucible" period. In 1912, Cushing was succeeded by Walter Dandy, whose work on experimental hydrocephalus and cerebrospinal fluid circulation led to the development of pneumoencephalography. The early days of neurosurgery evolved with close ties to general surgery, and so did the Hunterian laboratory. After Dandy began devoting his time to clinical work, general surgeons (first Jay McLean and then, in 1922, Ferdinand Lee) became the directors of the laboratory. Between 1928 and 1942, more than 150 original articles were issued from the Hunterian laboratory; these articles described significant advances in surgery, including pioneering

  11. Murine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years.

    Directory of Open Access Journals (Sweden)

    Rolf Knoth

    Full Text Available BACKGROUND: Essentially all knowledge about adult hippocampal neurogenesis in humans still comes from one seminal study by Eriksson et al. in 1998, although several others have provided suggestive findings. But only little information has been available in how far the situation in animal models would reflect the conditions in the adult and aging human brain. We therefore here mapped numerous features associated with adult neurogenesis in rodents in samples from human hippocampus across the entire lifespan. Such data would not offer proof of adult neurogenesis in humans, because it is based on the assumption that humans and rodents share marker expression patterns in adult neurogenesis. Nevertheless, together the data provide valuable information at least about the presence of markers, for which a link to adult neurogenesis might more reasonably be assumed than for others, in the adult human brain and their change with increasing age. METHODS AND FINDINGS: In rodents, doublecortin (DCX is transiently expressed during adult neurogenesis and within the neurogenic niche of the dentate gyrus can serve as a valuable marker. We validated DCX as marker of granule cell development in fetal human tissue and used DCX expression as seed to examine the dentate gyrus for additional neurogenesis-associated features across the lifespan. We studied 54 individuals and detected DCX expression between birth and 100 years of age. Caveats for post-mortem analyses of human tissues apply but all samples were free of signs of ischemia and activated caspase-3. Fourteen markers related to adult hippocampal neurogenesis in rodents were assessed in DCX-positive cells. Total numbers of DCX expressing cells declined exponentially with increasing age, and co-expression of DCX with the other markers decreased. This argued against a non-specific re-appearance of immature markers in specimen from old brains. Early postnatally all 14 markers were co-expressed in DCX-positive cells

  12. Evolution of iron minerals in a 100years-old Technosol. Consequences on Zn mobility

    Energy Technology Data Exchange (ETDEWEB)

    Coussy, Samuel; Grangeon, Sylvain; Bataillard, Philippe; Khodja, Hicham; Maubec, Nicolas; Faure, Pierre; Schwartz, Christophe; Dagois, Robin (BRGM- France); (CNRS-UMR)

    2017-03-01

    The prediction of the long term trace element mobility in anthropogenic soils would be a way to anticipate land management and should help in reusing slightly contaminated materials. In the present study, iron (Fe) and zinc (Zn) status evolution was investigated in a 100-year old Technosol. The site of investigation is an old brownfield located in the Nord-Pas-de-Calais region (France) which has not been reshaped since the beginning of the last century. The whole soil profile was sampled as a function of depth, and trace elements mobility at each depth was determined by batch leaching test. A specific focus on Fe and Zn status was carried out by bulk analyses, such as selective dissolution, X-ray diffraction (XRD) and X-ray absorption spectroscopy (XAS). Fe and Zn status in the profile samples was also studied using laterally resolved techniques such as μ-particle induced X-ray emission (μ-PIXE) and μ-Rutherford backscattering spectroscopy (μ-RBS). The results indicate that (i) Fe is mainly under Fe(III) form, except a minor contribution of Fe(II) in the deeper samples, (ii) some Fe species inherited from the past have been weathered and secondary minerals are constituted of metal-bearing sulphates and Fe (hydr)oxides, (iii) ferrihydrite is formed during pedogenesis (iv) 20 to 30% more Fe (hydr)oxides are present in the surface than in depth and (v) Zn has tetrahedral coordination and is sorbed to phases of increasing crystallinity when depth increases. Zn-bearing phases identified in the present study are: complex Fe, Mn, Zn sulphides, sulphates, organic matter, and ferrihydrite. Soil formation on such material does not induce a dramatic increase of Zn solubility since efficient scavengers are concomitantly formed in the system. However, Technosols are highly heterogeneous and widely differ from one place to another. The behavior examined in this study is not generic and will depend on the type of Technosol and on the secondary minerals formed as well as on

  13. 100 years of vegetation decline and recovery in Lake Fure, Denmark

    DEFF Research Database (Denmark)

    Jensen, Kaj Sand; Pedersen, Niels Lagergaard; Thorsgaard, Inge;

    2008-01-01

    by reducing water transparency from a summer mean of 5-6 m in the early 1900s to a minimum of 1.6 m at the peak of eutrophication, followed by recovery to a recent maximum of 4.1 m. • Macrophyte occurrence and abundance changed in accordance with altered environmental conditions and species' life-history...... the probability of recolonization. Species reaching Lake Fure may fail to establish because sediments have become richer in nutrients and organic matter and less consolidated, while shading and competition have increased from emergent reeds, tall submerged angiosperms and fast-growing macroalgae....

  14. 100 years of mapping the Holocene Rhine-Meuse delta plain: combining research and teaching

    Science.gov (United States)

    Cohen, K. M.; Stouthamer, E.; Hoek, W. Z.; Middelkoop, H.

    2012-04-01

    The history of modern soil, geomorphological and shallow geological mapping in the Holocene Rhine-Meuse delta plain goes back about 100 years. The delta plain is of very heterogeneous build up, with clayey and peaty flood basins, dissected by sandy fluvial distributary channel belts with fine textured levees grading into tidal-influenced rivers and estuaries. Several generations of precursor rivers occur as alluvial ridges and buried ribbon sands. They form an intricate network originating from repeated avulsions, back to 8000 years ago. Present rivers have been embanked since ca. 1250 AD and the delta plain (~ 3000 km2) has been reclaimed for agriculture. Soils are young and subject to oxidation and compaction. The first detailed field map of channel belts and floodbasins was made in 1926 by Vink, a geography teacher from Amsterdam. Soil mapping and Holocene geology gained interest after WW-II, with Wageningen soil scientists Edelman, Hoeksema and Pons taking lead. Utrecht University started teaching and research on the subject in 1959, launching an undergraduate mapping field course based on hand augering and field observation. An archive of borehole logs and local maps started to build up. Initially focused on soil mapping, from 1973 the course shifted to a geomorphological-geological focus. Berendsen took over supervision, introduced standard description protocols and legends and increased coring depth. This resulted in 1982 in his influential PhD thesis on the Rhine delta's genesis. New coring and sampling methods came and extensive 14C dating campaigns began. With steadily increasing numbers of students, accumulation of data speeded up, and increasingly larger parts of the delta were mapped. The academic mapping ran in parallel with soil survey and geological survey mapping campaigns. The computer was introduced in the field course and digital data archiving began in 1989. A series of PhD studies on thematic aspects of delta evolution and an increasing number

  15. Hypothetical conflict situations with friends and peers

    Directory of Open Access Journals (Sweden)

    Petrović Danijela S.

    2012-01-01

    Full Text Available This paper deals with age and sex differences in preferred strategies of conflict resolution in friendship and peer relationships. The study was conducted on the sample of 286 adolescents. Conflict resolution strategies have been investigated by the method of hypothetical conflict situations. For the purposes of this research, we have created an instrument consisting of 20 hypothetical situations, with the following subjects of conflict: breaking the agreement, non-compliance with opinion differences, provocations, dishonesty and stubbornness. Conflict resolution strategies we examined were giving in, withdrawal, competition and problem solving. The results have shown that problem solving is the dominant strategy of adolescents in conflict with friends, while in peer conflicts they more often opt for competition. Age differences are reflected in the fact that older adolescents are more likely to choose problem solving than younger, whereas younger adolescents are more likely to choose a retreat (withdrawal strategy than older. Girls are more prone to choosing problem solving than boys, who, on the other hand, tend to withdraw more than girls. Also, gender of the other person in the conflict is proved to be important - in conflict with male peers, adolescents choose competition to a greater extent and withdraw to a minor extent, compared to when they are in conflict with female peers. The results have practical implications as well. In programs for teaching constructive conflict resolution that are designed for younger adolescents there should be more emphasis on empowerment and training for assertive behaviour. In addition, when teaching about constructive conflict resolution strategies, it is important to consider the gender of adolescents as well as the gender of the person with whom they are in conflict.

  16. δ18O record and temperature change over the past 100 years in ice cores on the Tibetan Plateau

    Institute of Scientific and Technical Information of China (English)

    YAO; Tandong; GUO; Xuejun; Lonnie; Thompson; DUAN; Keqin; WANG; Ninglian; PU; Jianchen; XU; Baiqing; YANG; Xiaoxin; SUN; Weizhen

    2006-01-01

    The 213 m ice core from the Puruogangri Ice Field on the Tibetan Plateau facilitates the study of the regional temperature changes with its δ18O record of the past 100 years. Here we combine information from this core with that from the Dasuopu ice core (from the southern Tibetan Plateau), the Guliya ice core (from the northwestern Plateau) and the Dunde ice core (from the northeastern Plateau) to learn about the regional differences in temperature change across the Tibetan Plateau. The δ18O changes vary with region on the Plateau, the variations being especially large between South and North and between East and West. Moreover, these four ice cores present increasing δ18O trends, indicating warming on the Tibetan Plateau over the past 100 years. A comparative study of Northern Hemisphere (NH) temperature changes, the δ18O-reflected temperature changes on the Plateau, and available meteorological records show consistent trends in overall warming during the past 100 years.

  17. 100 years of superconductivity

    CERN Multimedia

    Globe Info

    2011-01-01

    Public lecture by Philippe Lebrun, who works at CERN on applications of superconductivity and cryogenics for particle accelerators. He was head of CERN’s Accelerator Technology Department during the LHC construction period. Centre culturel Jean Monnet, route de Gex Tuesday 11 October from 8.30 p.m. to 10.00 p.m. » Suitable for all – Admission free - Lecture in French » Number of places limited For further information: +33 (0)4 50 42 29 37

  18. 100 years of radar

    CERN Document Server

    Galati, Gaspare

    2016-01-01

    This book offers fascinating insights into the key technical and scientific developments in the history of radar, from the first patent, taken out by Hülsmeyer in 1904, through to the present day. Landmark events are highlighted and fascinating insights provided into the exceptional people who made possible the progress in the field, including the scientists and technologists who worked independently and under strict secrecy in various countries across the world in the 1930s and the big businessmen who played an important role after World War II. The book encourages multiple levels of reading. The author is a leading radar researcher who is ideally placed to offer a technical/scientific perspective as well as a historical one. He has taken care to structure and write the book in such a way as to appeal to both non-specialists and experts. The book is not sponsored by any company or body, either formally or informally, and is therefore entirely unbiased. The text is enriched by approximately three hundred ima...

  19. In Silico screening for functional candidates amongst hypothetical proteins

    DEFF Research Database (Denmark)

    Desler, Claus; Suravajhala, Prashanth; Sanderhoff, May

    2009-01-01

    BACKGROUND: The definition of a hypothetical protein is a protein that is predicted to be expressed from an open reading frame, but for which there is no experimental evidence of translation. Hypothetical proteins constitute a substantial fraction of proteomes of human as well as of other...... strategy where eukaryotic hypothetical proteins are sorted according to two criteria that can be reliably identified in silico: the presence of subcellular targeting signals and presence of characterized protein domains. To validate the selection strategy we applied it on a database of human hypothetical......, defined as hypothetical in 2006, have later been characterized as mitochondrial. CONCLUSION: Among the total amount of human proteins hypothetical in 2006, 21% have later been experimentally characterized and 6% of those have been shown to have a role in a mitochondrial context. In contrast, among...

  20. Prediction of permafrost distribution on the Qinghai-Tibet Plateau in the next 50 and 100 years

    Institute of Scientific and Technical Information of China (English)

    NAN Zhuotong; LI Shuxun; CHENG Guodong

    2005-01-01

    Intergovernmental Panel on Climate Change (IPCC) in 2001 reported that the Earth air temperature would rise by 1.4-5.8℃ and 2.5℃ on average by the year 2100. China regional climate model results also showed that the air temperature on the Qinghai-Tibet Plateau (QTP) would increase by 2.2-2.6℃ in the next 50 years. A numerical permafrost model was ed to predict the changes of permafrost distribution on the QTP over the next 50 and 100 years under the two climatic warming scenarios, i.e. 0.02℃/a, the lower value of IPCC's estimation, and 0.052℃/a, the higher value predicted by Qin et al. Simulation results show that ( i ) in the case of 0.02℃/a air-temperature rise, permafrost area on the QTP will shrink about 8.8% in the next 50 years, and high temperature permafrost with mean annual ground temperature (MAGT) higher than -0.11℃ may turn into seasonal frozen soils. In the next 100 years, permafrost with MAGT higher than -0.5℃ will disappear and the permafrost area will shrink up to 13.4%. (ii) In the case of 0.052℃/a air-temperature rise, permafrost area on the QTP will reduce about 13.5% after 50 years. More remarkable degradation will take place after 100 years, and permafrost area will reduce about 46%. Permafrost with MAGT higher than -2℃ will turn into seasonal frozen soils and even unfrozen soils.

  1. Induced metamorphosis in crustacean y-larvae: towards a solution to a 100-year-old riddle

    DEFF Research Database (Denmark)

    Glenner, Henrik; Høeg, Jens T; Grygier, Mark J

    2008-01-01

    BACKGROUND: The y-larva, a crustacean larval type first identified more than 100 years ago, has been found in marine plankton samples collected in the arctic, temperate and tropical regions of all oceans. The great species diversity found among y-larvae (we have identified more than 40 species......-larvae into a novel, highly reduced juvenile stage by applying the crustacean molting hormone 20-HE. The new stage is slug-like, unsegmented and lacks both limbs and almost all other traits normally characterizing arthropods, but it is capable of vigorous peristaltic motions. CONCLUSION: From our observations on live...

  2. A MODEL TO EVALUATE 100-YEAR ENERGY-MIX SCENARIOS TO FACILITATE DEEP DECARBONIZATION IN THE SOUTHEASTERN UNITED STATES

    Energy Technology Data Exchange (ETDEWEB)

    Adkisson, Mary A [ORNL; Qualls, A L [ORNL

    2016-08-01

    The Southeast United States consumes approximately one billion megawatt-hours of electricity annually; roughly two-thirds from carbon dioxide (CO2) emitting sources. The balance is produced by non-CO2 emitting sources: nuclear power, hydroelectric power, and other renewables. Approximately 40% of the total CO2 emissions come from the electric grid. The CO2 emitting sources, coal, natural gas, and petroleum, produce approximately 372 million metric tons of CO2 annually. The rest is divided between the transportation sector (36%), the industrial sector (20%), the residential sector (3%), and the commercial sector (2%). An Energy Mix Modeling Analysis (EMMA) tool was developed to evaluate 100-year energy mix strategies to reduce CO2 emissions in the southeast. Current energy sector data was gathered and used to establish a 2016 reference baseline. The spreadsheet-based calculation runs 100-year scenarios based on current nuclear plant expiration dates, assumed electrical demand changes from the grid, assumed renewable power increases and efficiency gains, and assumed rates of reducing coal generation and deployment of new nuclear reactors. Within the model, natural gas electrical generation is calculated to meet any demand not met by other sources. Thus, natural gas is viewed as a transitional energy source that produces less CO2 than coal until non-CO2 emitting sources can be brought online. The annual production of CO2 and spent nuclear fuel and the natural gas consumed are calculated and summed. A progression of eight preliminary scenarios show that nuclear power can substantially reduce or eliminate demand for natural gas within 100 years if it is added at a rate of only 1000 MWe per year. Any increases in renewable energy or efficiency gains can offset the need for nuclear power. However, using nuclear power to reduce CO2 will result in significantly more spent fuel. More efficient advanced reactors can only marginally reduce the amount of spent fuel generated in

  3. How phenobarbital revolutionized epilepsy therapy: the story of phenobarbital therapy in epilepsy in the last 100 years.

    Science.gov (United States)

    Yasiry, Zeid; Shorvon, Simon D

    2012-12-01

    Phenobarbital (phenobarbitone) was first used as an antiepileptic drug 100 years ago, in 1912. This article tells the story of the discovery of its antiepileptic action, its early development, and the subsequent course of its clinical use over the 100-year period. The side effects, pharmacokinetics, and misuse of barbiturates are considered, along with the more recent clinical trials and the drug's current clinical utilization. The introduction of controlled drug regulations, the comparative cost of phenobarbital, and its inclusion on the World Health Organization (WHO) essential drug list are discussed. It is one of the few drugs on the formulary in 1912 that is still listed today, and remarkably its efficacy in epilepsy has not been significantly bettered. The current recommendation by the WHO is that phenobarbital should be offered as the first option for therapy for convulsive epilepsy in adults and children if availability can be ensured. This is rated as a strong recommendation because of the proven efficacy and low cost of phenobarbital, and despite its perceived side-effect profile and the practical problems of access. Whether this recommendation puts "a hierarchy on the brain," as has been suggested, is arguable. Much still needs to be learned about the drug's effects, and the issues raised by phenobarbital have lessons for all antiepileptic drug therapy. Wiley Periodicals, Inc. © 2012 International League Against Epilepsy.

  4. Preschool Children's Judgments about Hypothetical and Actual Transgressions.

    Science.gov (United States)

    Smetana, Judith G.; And Others

    1993-01-01

    Examined three and four year olds' judgments about transgressions. Children judged moral transgressions to be more serious, punishable, and wrong than conventional transgressions; hypothetical transgressions to be more wrong independent of rules than actual transgressions; and hypothetical moral transgressions to be more independent of rules than…

  5. Quantification of uncertainties in the 100-year flow at an ungaged site near a gaged station and its application in Georgia

    Science.gov (United States)

    Cho, Huidae; Bones, Emma

    2016-08-01

    The Federal Emergency Management Agency has introduced the concept of the "1-percent plus" flow to incorporate various uncertainties in estimation of the 100-year or 1-percent flow. However, to the best of the authors' knowledge, no clear directions for calculating the 1-percent plus flow have been defined in the literature. Although information about standard errors of estimation and prediction is provided along with the regression equations that are often used to estimate the 1-percent flow at ungaged sites, uncertainty estimation becomes more complicated when there is a nearby gaged station because regression flows and the peak flow estimate from a gage analysis should be weighted to compute the weighted estimate of the 1-percent flow. In this study, an equation for calculating the 1-percent plus flow at an ungaged site near a gaged station is analytically derived. Also, a detailed process is introduced for calculating the 1-percent plus flow for an ungaged site near a gaged station in Georgia as an example and a case study is performed. This study provides engineers and practitioners with a method that helps them better assess flood risks and develop mitigation plans accordingly.

  6. Simulated carbon and water processes of forest ecosystems in Forsmark and Oskarshamn during a 100-year period

    Energy Technology Data Exchange (ETDEWEB)

    Gustafsson, David; Jansson, Per-Erik [Royal Inst. of Technology, Stockholm (Sweden). Dept. of Land and Water Resources Engineering; Gaerdenaes, Annemieke [Swedish Univ. of Agricultural Sciences, Uppsala (Sweden). Dept. of Soil Sciences; Eckersten, Henrik [Swedish Univ. of Agricultural Sciences, Uppsala (Sweden). Dept. of Crop Production Ecology

    2006-12-15

    The Swedish Nuclear Fuel and Waste Management Co (SKB) is currently investigating the Forsmark and Oskarshamn areas for possible localisation of a repository for spent nuclear fuel. Important components of the investigations are characterizations of the land surface ecosystems in the areas with respect to hydrological and biological processes, and their implications for the fate of radionuclide contaminants entering the biosphere from a shallow groundwater contamination. In this study, we simulate water balance and carbon turnover processes in forest ecosystems representative for the Forsmark and Oskarshamn areas for a 100-year period using the ecosystem process model CoupModel. The CoupModel describes the fluxes of water and matter in a one-dimensional soil-vegetation-atmosphere system, forced by time series of meteorological variables. The model has previously been parameterized for many of the vegetation systems that can be found in the Forsmark and Oskarshamn areas: spruce/pine forests, willow, grassland and different agricultural crops. This report presents a platform for further use of models like CoupModel for investigations of radionuclide turnover in the Forsmark and Oskarshamn area based on SKB data, including a data set of meteorological forcing variables for Forsmark 1970-2004, suitable for simulations of a 100-year period representing the present day climate, a hydrological parameterization of the CoupModel for simulations of the forest ecosystems in the Forsmark and Oskarshamn areas, and simulated carbon budgets and process descriptions for Forsmark that correspond to a possible steady state of the soil storage of the forest ecosystem.

  7. In Silico screening for functional candidates amongst hypothetical proteins

    Directory of Open Access Journals (Sweden)

    Sanderhoff May

    2009-09-01

    Full Text Available Abstract Background The definition of a hypothetical protein is a protein that is predicted to be expressed from an open reading frame, but for which there is no experimental evidence of translation. Hypothetical proteins constitute a substantial fraction of proteomes of human as well as of other eukaryotes. With the general belief that the majority of hypothetical proteins are the product of pseudogenes, it is essential to have a tool with the ability of pinpointing the minority of hypothetical proteins with a high probability of being expressed. Results Here, we present an in silico selection strategy where eukaryotic hypothetical proteins are sorted according to two criteria that can be reliably identified in silico: the presence of subcellular targeting signals and presence of characterized protein domains. To validate the selection strategy we applied it on a database of human hypothetical proteins dating to 2006 and compared the proteins predicted to be expressed by our selecting strategy, with their status in 2008. For the comparison we focused on mitochondrial proteins, since considerable amounts of research have focused on this field in between 2006 and 2008. Therefore, many proteins, defined as hypothetical in 2006, have later been characterized as mitochondrial. Conclusion Among the total amount of human proteins hypothetical in 2006, 21% have later been experimentally characterized and 6% of those have been shown to have a role in a mitochondrial context. In contrast, among the selected hypothetical proteins from the 2006 dataset, predicted by our strategy to have a mitochondrial role, 53-62% have later been experimentally characterized, and 85% of these have actually been assigned a role in mitochondria by 2008. Therefore our in silico selection strategy can be used to select the most promising candidates for subsequent in vitro and in vivo analyses.

  8. Side effects and accounting aspects of hypothetical large-scale Southern Ocean iron fertilization

    Directory of Open Access Journals (Sweden)

    A. Oschlies

    2010-12-01

    Full Text Available Recent suggestions to slow down the increase in atmospheric carbon dioxide have included ocean fertilization by addition of the micronutrient iron to Southern Ocean surface waters, where a number of natural and artificial iron fertilization experiments have shown that low ambient iron concentrations limit phytoplankton growth. Using a coupled carbon-climate model with the marine biology's response to iron addition calibrated against data from natural iron fertilization experiments, we examine biogeochemical side effects of a hypothetical large-scale Southern Ocean Iron Fertilization (OIF that need to be considered when attempting to account for possible OIF-induced carbon offsets. In agreement with earlier studies our model simulates an OIF-induced increase in local air-sea CO2 fluxes by about 73 GtC over a 100-year period, which amounts to about 48% of the OIF-induced increase in organic carbon export out of the fertilized area. Offsetting CO2 return fluxes outside the region and after stopping the fertilization at 1, 7, 10, 50, and 100 years are quantified for a typical accounting period of 100 years. For continuous Southern Ocean iron fertilization, the CO2 return flux outside the fertilized area cancels about 20% of the fertilization-induced CO2 air-sea flux within the fertilized area on a 100-yr timescale. This "leakage" effect has a radiative impact more than twice as large as the simulated enhancement of marine N2O emissions. Other side effects not yet discussed in terms of accounting schemes include a decrease in Southern Ocean oxygen levels and a simultaneous shrinking of tropical suboxic areas, and accelerated ocean acidification in the entire water column in the Southern Ocean at the expense of reduced globally-averaged surface-water acidification. A prudent approach to account for the OIF-induced carbon sequestration would account for global air-sea CO2 fluxes rather

  9. CoSMoS Southern California v3.0 Phase 1 (100-year storm) storm hazard projections

    Science.gov (United States)

    Barnard, Patrick; Erikson, Li; Foxgrover, Amy; O'Neill, Andrea; Herdman, Liv

    2016-01-01

    The Coastal Storm Modeling System (CoSMoS) makes detailed predictions (meter-scale) over large geographic scales (100s of kilometers) of storm-induced coastal flooding and erosion for both current and future sea-level rise (SLR) scenarios. CoSMoS v3.0 for Southern California shows projections for future climate scenarios (sea-level rise and storms) to provide emergency responders and coastal planners with critical storm-hazards information that can be used to increase public safety, mitigate physical damages, and more effectively manage and allocate resources within complex coastal settings. Phase I data for Southern California include flood-hazard information for the coast from the Mexican Border to Pt. Conception for a 100-year storm scenario and sea-level rise 0 - 2 m. Changes from previous data releases may be reflected in some areas. Data are complete for the information presented but are considered preliminary; changes may be reflected in the full data release (Phase II) in summer 2016.

  10. Induced metamorphosis in crustacean y-larvae: Towards a solution to a 100-year-old riddle

    Directory of Open Access Journals (Sweden)

    Grygier Mark J

    2008-05-01

    Full Text Available Abstract Background The y-larva, a crustacean larval type first identified more than 100 years ago, has been found in marine plankton samples collected in the arctic, temperate and tropical regions of all oceans. The great species diversity found among y-larvae (we have identified more than 40 species at our study site alone indicates that the adult organism may play a significant ecological role. However, despite intense efforts, the adult y-organism has never been identified, and nothing is therefore known about its biology. Results We have successfully and repeatedly induced metamorphosis of y-larvae into a novel, highly reduced juvenile stage by applying the crustacean molting hormone 20-HE. The new stage is slug-like, unsegmented and lacks both limbs and almost all other traits normally characterizing arthropods, but it is capable of vigorous peristaltic motions. Conclusion From our observations on live and preserved material we conclude that adult Facetotecta are endoparasitic in still to be identified marine hosts and with a juvenile stage that represents a remarkable convergence to that seen in parasitic barnacles (Crustacea Cirripedia Rhizocephala. From the distribution and abundance of facetotectan y-larvae in the world's oceans we furthermore suggest that these parasites are widespread and could play an important role in the marine environment.

  11. PeakWorks

    Energy Technology Data Exchange (ETDEWEB)

    2016-11-30

    The PeakWorks software is designed to assist in the quantitative analysis of atom probe tomography (APT) generated mass spectra. Specifically, through an interactive user interface, mass peaks can be identified automatically (defined by a threshold) and/or identified manually. The software then provides a means to assign specific elemental isotopes (including more than one) to each peak. The software also provides a means for the user to choose background subtraction of each peak based on background fitting functions, the choice of which is left to the users discretion. Peak ranging (the mass range over which peaks are integrated) is also automated allowing the user to chose a quantitative range (e.g. full-widthhalf- maximum). The software then integrates all identified peaks, providing a background-subtracted composition, which also includes the deconvolution of peaks (i.e. those peaks that happen to have overlapping isotopic masses). The software is also able to output a 'range file' that can be used in other software packages, such as within IVAS. A range file lists the peak identities, the mass range of each identified peak, and a color code for the peak. The software is also able to generate 'dummy' peak ranges within an outputted range file that can be used within IVAS to provide a means for background subtracted proximity histogram analysis.

  12. Economic Valuation of Hypothetical Paratransit Retrofitting

    Directory of Open Access Journals (Sweden)

    Naili Huda

    2015-06-01

    Full Text Available This paper describes a feasibility analysis of conventional and retrofitted paratransits, comparing economic performance of conventional paratransit with those using lead acid and lithium batteries. Research object is Dago-Kalapa paratransit in Bandung, West Java, travelling the distance of 11 km in town, under 8 peak hour operation. After calculating the estimated annual cost and benefit; net present value (NPV, payback period (PBP and internal rate of return (IRR then were quantified to provide feasibility description of those three paratransits. In addition, a sensitivity analysis regarding discount rate, gasoline price and battery price is given to offer broader sense of factors embraced. It is found that both gasoline and lead acid paratransit have big NPVs with only slight differences, while lithium paratransit has negative NPV. This phenomenon applies to their PBPs and IRRs as well. Only when gasoline costs reaches IDR 15,000 will electric paratransit prevails over conventional one. Thus, it can be inferred that at the moment, paratransit runs with gasoline is still the most cost effective compared to its counterparts. However, starting retrofitting from now is endorsed due to its environmental benefit. Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;}

  13. The protection of Canfranc Internation Railway Sattion against natural risks. Analysis and evaluation of its effectiveness 100 years later.

    Science.gov (United States)

    Fabregas, S.; Hurtado, R.; Mintegui, J.

    2012-04-01

    In the late XIXth century and early XXth century, the international railway station in Canfranc "Los Arañones" is built in the Central Pyrenees of Huesca in Spain, along the border between France and Spain. Just after starting the construction of the huge station (250 m long), it was found that natural hazards such as flash floods, landslides, falling blocks and avalanches affected it and compromised the safety of users and infrastructures.Quickly, hydrological restoration works were carried out along "Los Arañones" gorgers basins to reduce joint residual risks. Longitudinal and transversal dams for floods, a large reforestation work to prevent against falling blocks, erosion, flooding and regarding avalanches stone walls were built, as well as benches of grit, snow rakes, and "empty dams", which were created as experimental structures to dissipate the energy of the avalanche in the track zone and wich do not exist anywhere else in the world. All the works were carried out mainly by hand, with materials such as stone, cement and iron. Over 2,500,000 holes were made for planting more than 15 different species of trees, and more than 400,000 tons of stone were moved to build more than 12 different kinds of control measures.It is essential to emphasize the empirical nature of these works and Canfranc's function as a "laboratory or field tests", with most of its structures still effective 100 years after its construction. The works involved about 30% of the total cost of the station in the early XX century. Nowadays to have an "equivalent protection" with the current technology, around 100 million euro should be invested. It is also necessary to validate the current effectiveness of such works, its maintenance task and the protective role of the forest.

  14. Paniek over Peak Food

    NARCIS (Netherlands)

    Koning, N.B.J.

    2015-01-01

    Het kon niet uitblijven. De groei van de voedselproductie stagneert en na Peak Oil dreigt nu Peak Food. Onzin, vindt Niek Koning, die zogenaamde peak is een van de toppen in een langjarige golfbeweging op de landbouwmarkten. Toch zijn er genoeg redenen om je zorgen te maken over de wereldvoedselvoor

  15. 100-Year Floodplains, NC Floodplain Mapping Program data, Published in 2007, 1:12000 (1in=1000ft) scale, Iredell County GIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at 1:12000 (1in=1000ft) scale, was produced all or in part from LIDAR information as of 2007. It is described as 'NC...

  16. 100-Year Floodplains, FEMA Floodway and Flood Boundary Maps, Published in 2005, 1:24000 (1in=2000ft) scale, Lafayette County Land Records.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at 1:24000 (1in=2000ft) scale, was produced all or in part from Other information as of 2005. It is described as 'FEMA...

  17. 100-Year Floodplains, FEMA Flood Zones, Published in 2010, 1:2400 (1in=200ft) scale, Effingham County Board Of Commissioners.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Published Reports/Deeds information as of 2010. It is...

  18. 100-Year Floodplains, Flood plains from FEMA, Published in 2003, 1:600 (1in=50ft) scale, Town of Cary NC.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at 1:600 (1in=50ft) scale, was produced all or in part from LIDAR information as of 2003. It is described as 'Flood...

  19. 100-Year Floodplains, FEMA DFIRM preliminary map out now, to be published in 2009, Published in 2009, 1:12000 (1in=1000ft) scale, Brown County, WI.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at 1:12000 (1in=1000ft) scale, was produced all or in part from Other information as of 2009. It is described as 'FEMA...

  20. 100-Year Floodplains, Data provided by FEMA and WI DNR, Published in 2009, 1:2400 (1in=200ft) scale, Dane County Land Information Office.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at 1:2400 (1in=200ft) scale as of 2009. It is described as 'Data provided by FEMA and WI DNR'. Data by this publisher...

  1. The story of the Hawaiian Volcano Observatory -- A remarkable first 100 years of tracking eruptions and earthquakes

    Science.gov (United States)

    Babb, Janet L.; Kauahikaua, James P.; Tilling, Robert I.

    2011-01-01

    The year 2012 marks the centennial of the Hawaiian Volcano Observatory (HVO). With the support and cooperation of visionaries, financiers, scientists, and other individuals and organizations, HVO has successfully achieved 100 years of continuous monitoring of Hawaiian volcanoes. As we celebrate this milestone anniversary, we express our sincere mahalo—thanks—to the people who have contributed to and participated in HVO’s mission during this past century. First and foremost, we owe a debt of gratitude to the late Thomas A. Jaggar, Jr., the geologist whose vision and efforts led to the founding of HVO. We also acknowledge the pioneering contributions of the late Frank A. Perret, who began the continuous monitoring of Kīlauea in 1911, setting the stage for Jaggar, who took over the work in 1912. Initial support for HVO was provided by the Massachusetts Institute of Technology (MIT) and the Carnegie Geophysical Laboratory, which financed the initial cache of volcano monitoring instruments and Perret’s work in 1911. The Hawaiian Volcano Research Association, a group of Honolulu businessmen organized by Lorrin A. Thurston, also provided essential funding for HVO’s daily operations starting in mid-1912 and continuing for several decades. Since HVO’s beginning, the University of Hawaiʻi (UH), called the College of Hawaii until 1920, has been an advocate of HVO’s scientific studies. We have benefited from collaborations with UH scientists at both the Hilo and Mänoa campuses and look forward to future cooperative efforts to better understand how Hawaiian volcanoes work. The U.S. Geological Survey (USGS) has operated HVO continuously since 1947. Before then, HVO was under the administration of various Federal agencies—the U.S. Weather Bureau, at the time part of the Department of Agriculture, from 1919 to 1924; the USGS, which first managed HVO from 1924 to 1935; and the National Park Service from 1935 to 1947. For 76 of its first 100 years, HVO has been

  2. Accumulation of pharmaceuticals, Enterococcus, and resistance genes in soils irrigated with wastewater for zero to 100 years in central Mexico.

    Directory of Open Access Journals (Sweden)

    Philipp Dalkmann

    Full Text Available Irrigation with wastewater releases pharmaceuticals, pathogenic bacteria, and resistance genes, but little is known about the accumulation of these contaminants in the environment when wastewater is applied for decades. We sampled a chronosequence of soils that were variously irrigated with wastewater from zero up to 100 years in the Mezquital Valley, Mexico, and investigated the accumulation of ciprofloxacin, enrofloxacin, sulfamethoxazole, trimethoprim, clarithromycin, carbamazepine, bezafibrate, naproxen, diclofenac, as well as the occurrence of Enterococcus spp., and sul and qnr resistance genes. Total concentrations of ciprofloxacin, sulfamethoxazole, and carbamazepine increased with irrigation duration reaching 95% of their upper limit of 1.4 µg/kg (ciprofloxacin, 4.3 µg/kg (sulfamethoxazole, and 5.4 µg/kg (carbamazepine in soils irrigated for 19-28 years. Accumulation was soil-type-specific, with largest accumulation rates in Leptosols and no time-trend in Vertisols. Acidic pharmaceuticals (diclofenac, naproxen, bezafibrate were not retained and thus did not accumulate in soils. We did not detect qnrA genes, but qnrS and qnrB genes were found in two of the irrigated soils. Relative concentrations of sul1 genes in irrigated soils were two orders of magnitude larger (3.15 × 10(-3 ± 0.22 × 10(-3 copies/16S rDNA than in non-irrigated soils (4.35 × 10(-5± 1.00 × 10(-5 copies/16S rDNA, while those of sul2 exceeded the ones in non-irrigated soils still by a factor of 22 (6.61 × 10(-4 ± 0.59 × 10(-4 versus 2.99 × 10(-5 ± 0.26 × 10(-5 copies/16S rDNA. Absolute numbers of sul genes continued to increase with prolonging irrigation together with Enterococcus spp. 23S rDNA and total 16S rDNA contents. Increasing total concentrations of antibiotics in soil are not accompanied by increasing relative abundances of resistance genes. Nevertheless, wastewater irrigation enlarges the absolute concentration of resistance genes in soils due to a

  3. Comparing hypothetical versus non-hypothetical methods for measuring willingness to pay in a food context

    Directory of Open Access Journals (Sweden)

    Laura Martínez-Carrasco

    2015-12-01

    Full Text Available Choosing a valid procedure to measure willingness to pay (WTP is crucial for designating optimum price policies or for evaluating the demand for new products. This study compares two methods for obtaining WTP in a food context: a random nth price auction and an open-ended contingent valuation (CV question. Participants were regular salad tomato buyers of Alicante and they were randomly assigned to one of the two treatments. The products about which they would show their WTP were traditional tomato varieties. Both treatments were divided into three stages: in the first stage the only available information was a reference price for the tomatoes. In stages 2 and 3 we revealed the local origin and the organic grown of the tomatoes respectively. Our results show that in the auction the percentage of participants willing to pay the same or more than the reference price was between 20 and 30%. In the CV method this percentage was between 40 and 65%. The mean WTP in the auction, considering the whole of the individuals, was situated between 1.90 and 2.13 €/kg. These same results obtained through the CV were situated between 2.54 and 3.21 €/kg. The results confirmed the findings of previous papers in which the hypothetical bias of CV was clarified because it yields higher values for WTP than the auction, especially when referring to the number of individuals willing to pay more. Additionally, hedonic price models were estimated for the prices obtained by both methods with the result that in all the models, WTP was directly related to the price paid for the latest purchase of tomatoes.

  4. Comparing hypothetical versus non-hypothetical methods for measuring willingness to pay in a food context

    Energy Technology Data Exchange (ETDEWEB)

    Martínez-Carrasco, L.; Brugarolas, M.; Martínez-Poveda, A.; Ruiz-Martínez, J.J.

    2015-07-01

    Choosing a valid procedure to measure willingness to pay (WTP) is crucial for designating optimum price policies or for evaluating the demand for new products. This study compares two methods for obtaining WTP in a food context: a random nth price auction and an open-ended contingent valuation (CV) question. Participants were regular salad tomato buyers of Alicante and they were randomly assigned to one of the two treatments. The products about which they would show their WTP were traditional tomato varieties. Both treatments were divided into three stages: in the first stage the only available information was a reference price for the tomatoes. In stages 2 and 3 we revealed the local origin and the organic grown of the tomatoes respectively. Our results show that in the auction the percentage of participants willing to pay the same or more than the reference price was between 20 and 30%. In the CV method this percentage was between 40 and 65%. The mean WTP in the auction, considering the whole of the individuals, was situated between 1.90 and 2.13 €/kg. These same results obtained through the CV were situated between 2.54 and 3.21 €/kg. The results confirmed the findings of previous papers in which the hypothetical bias of CV was clarified because it yields higher values for WTP than the auction, especially when referring to the number of individuals willing to pay more. Additionally, hedonic price models were estimated for the prices obtained by both methods with the result that in all the models, WTP was directly related to the price paid for the latest purchase of tomatoes. (Author)

  5. Are Bragg Peaks Gaussian?

    Science.gov (United States)

    Hammouda, Boualem

    2014-01-01

    It is common practice to assume that Bragg scattering peaks have Gaussian shape. The Gaussian shape function is used to perform most instrumental smearing corrections. Using Monte Carlo ray tracing simulation, the resolution of a realistic small-angle neutron scattering (SANS) instrument is generated reliably. Including a single-crystal sample with large d-spacing, Bragg peaks are produced. Bragg peaks contain contributions from the resolution function and from spread in the sample structure. Results show that Bragg peaks are Gaussian in the resolution-limited condition (with negligible sample spread) while this is not the case when spread in the sample structure is non-negligible. When sample spread contributes, the exponentially modified Gaussian function is a better account of the Bragg peak shape. This function is characterized by a non-zero third moment (skewness) which makes Bragg peaks asymmetric for broad neutron wavelength spreads. PMID:26601025

  6. Lexical exponents of hypothetical modality in Polish and Lithuanian

    Directory of Open Access Journals (Sweden)

    Roman Roszko

    2015-11-01

    To analyse both the languages there is used the method of theoretical contrastive studies, which the most important features are: (1 orienting the studies from the content grounds to the formal grounds, (2 using a semantic interlanguage as tertium comparationis. First of all, the content of hypothetical modality and its definition and paraphrase is given here. Next, the gradational character of this category is discussed. There are distinguished six groups of lexemes expressing the corresponding degrees of hypothetical modality — from a shadow of uncertainty (minimal degree of probability to an almost complete certainty (maximum degree of probability. The experimental Polish-Lithuanian corpus is widely applied in the studies.

  7. Peak Experience Project

    Science.gov (United States)

    Scott, Daniel G.; Evans, Jessica

    2010-01-01

    This paper emerges from the continued analysis of data collected in a series of international studies concerning Childhood Peak Experiences (CPEs) based on developments in understanding peak experiences in Maslow's hierarchy of needs initiated by Dr Edward Hoffman. Bridging from the series of studies, Canadian researchers explore collected…

  8. Peak Experience Project

    Science.gov (United States)

    Scott, Daniel G.; Evans, Jessica

    2010-01-01

    This paper emerges from the continued analysis of data collected in a series of international studies concerning Childhood Peak Experiences (CPEs) based on developments in understanding peak experiences in Maslow's hierarchy of needs initiated by Dr Edward Hoffman. Bridging from the series of studies, Canadian researchers explore collected…

  9. Preferences for Physically Disabled Counselors in Hypothetical Counseling Situations

    Science.gov (United States)

    Mitchell, David C.; Frederickson, William A.

    1975-01-01

    The preferences of 320 undergraduate students for one of three disabled counselors or for a nondisabled counselor on each of Brabham and Thoreson's 20 hypothetical counseling situations were obtained. Significant counselor preferences existed for 18 of the 20 situations, and when categorized by sex, significant counselor preferences existed for 4…

  10. Genome-wide screens for expressed hypothetical proteins

    DEFF Research Database (Denmark)

    Madsen, Claus Desler; Durhuus, Jon Ambæk; Rasmussen, Lene Juel

    2012-01-01

    A hypothetical protein (HP) is defined as a protein that is predicted to be expressed from an open reading frame, but for which there is no experimental evidence of translation. HPs constitute a substantial fraction of proteomes of human as well as of other organisms. With the general belief...

  11. The Chandrasekhar's Equation for Two-Dimensional Hypothetical White Dwarfs

    CERN Document Server

    De, Sanchari

    2014-01-01

    In this article we have extended the original work of Chandrasekhar on the structure of white dwarfs to the two-dimensional case. Although such two-dimensional stellar objects are hypothetical in nature, we strongly believe that the work presented in this article may be prescribed as Master of Science level class problem for the students in physics.

  12. Scaffolding for Argumentation in Hypothetical and Theoretical Biology Concepts

    Science.gov (United States)

    Weng, Wan-Yun; Lin, Yu-Ren; She, Hsiao-Ching

    2017-01-01

    The present study investigated the effects of online argumentation scaffolding on students' argumentation involving hypothetical and theoretical biological concepts. Two types of scaffolding were developed in order to improve student argumentation: continuous scaffolding and withdraw scaffolding. A quasi-experimental design was used with four…

  13. Hypothetical Markets: Educational Application of Ronald Dworkin's "Sovereign Virtue"

    Science.gov (United States)

    Gough, Stephen

    2006-01-01

    The purpose of this paper is to consider, in principle and at the most general level, a particular possible approach to educational policy-making. This approach involves an education-specific application of the notion of hypothetical markets first developed in Ronald Dworkin's book "Sovereign Virtue: The theory and practice of equality" (2000).…

  14. A Hypothetical Learning Trajectory for Conceptualizing Matrices as Linear Transformations

    Science.gov (United States)

    Andrews-Larson, Christine; Wawro, Megan; Zandieh, Michelle

    2017-01-01

    In this paper, we present a hypothetical learning trajectory (HLT) aimed at supporting students in developing flexible ways of reasoning about matrices as linear transformations in the context of introductory linear algebra. In our HLT, we highlight the integral role of the instructor in this development. Our HLT is based on the "Italicizing…

  15. Substance Abuse Counselors and Moral Reasoning: Hypothetical and Authentic Dilemmas

    Science.gov (United States)

    Sias, Shari M.

    2009-01-01

    This exploratory study examined the assumption that the level of moral reasoning (Defining Issues Test; J. R. Rest, 1986) used in solving hypothetical and authentic dilemmas is similar for substance abuse counselors (N = 188). The statistical analyses used were paired-sample t tests, Pearson product-moment correlation, and simultaneous multiple…

  16. The central peak revisited

    Energy Technology Data Exchange (ETDEWEB)

    Shirane, G.

    1995-10-27

    The central peak in SrTiO{sub 3} was first observed by Riste and his collaborators in 1971. This was one of the key discoveries leading to an understanding of the dynamics of phase transitions. The most recent discovery of two length scales in SrTiO{sub 3} motivated a reinvestigation of the soft phonon and associated central peak by neutron scattering. These recent experiments shed new light on the nature of the central peak. It is now well established to be strongly sample dependent and it originates from defects in bulk crystals.

  17. Pikes Peak, Colorado

    Science.gov (United States)

    Brunstein, Craig; Quesenberry, Carol; Davis, John; Jackson, Gene; Scott, Glenn R.; D'Erchia, Terry D.; Swibas, Ed; Carter, Lorna; McKinney, Kevin; Cole, Jim

    2006-01-01

    For 200 years, Pikes Peak has been a symbol of America's Western Frontier--a beacon that drew prospectors during the great 1859-60 Gold Rush to the 'Pikes Peak country,' the scenic destination for hundreds of thousands of visitors each year, and an enduring source of pride for cities in the region, the State of Colorado, and the Nation. November 2006 marks the 200th anniversary of the Zebulon M. Pike expedition's first sighting of what has become one of the world's most famous mountains--Pikes Peak. In the decades following that sighting, Pikes Peak became symbolic of America's Western Frontier, embodying the spirit of Native Americans, early explorers, trappers, and traders who traversed the vast uncharted wilderness of the Western Great Plains and the Southern Rocky Mountains. High-quality printed paper copies of this poster are available at no cost from Information Services, U.S. Geological Survey (1-888-ASK-USGS).

  18. Peak Oil, Peak Coal and Climate Change

    Science.gov (United States)

    Murray, J. W.

    2009-05-01

    Research on future climate change is driven by the family of scenarios developed for the IPCC assessment reports. These scenarios create projections of future energy demand using different story lines consisting of government policies, population projections, and economic models. None of these scenarios consider resources to be limiting. In many of these scenarios oil production is still increasing to 2100. Resource limitation (in a geological sense) is a real possibility that needs more serious consideration. The concept of 'Peak Oil' has been discussed since M. King Hubbert proposed in 1956 that US oil production would peak in 1970. His prediction was accurate. This concept is about production rate not reserves. For many oil producing countries (and all OPEC countries) reserves are closely guarded state secrets and appear to be overstated. Claims that the reserves are 'proven' cannot be independently verified. Hubbert's Linearization Model can be used to predict when half the ultimate oil will be produced and what the ultimate total cumulative production (Qt) will be. US oil production can be used as an example. This conceptual model shows that 90% of the ultimate US oil production (Qt = 225 billion barrels) will have occurred by 2011. This approach can then be used to suggest that total global production will be about 2200 billion barrels and that the half way point will be reached by about 2010. This amount is about 5 to 7 times less than assumed by the IPCC scenarios. The decline of Non-OPEC oil production appears to have started in 2004. Of the OPEC countries, only Saudi Arabia may have spare capacity, but even that is uncertain, because of lack of data transparency. The concept of 'Peak Coal' is more controversial, but even the US National Academy Report in 2007 concluded only a small fraction of previously estimated reserves in the US are actually minable reserves and that US reserves should be reassessed using modern methods. British coal production can be

  19. Peak of Achievement

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    China’s first inland research station on the highest peak of Antarctic progresses smoothly China will complete the construction of its first inland Antarctic research station at Dome A,the highest polar icecap peak at 4,093 meters above sea level,next year,according to a south pole scientist involved in the project. "The preparatory work for the new sta-

  20. Dr Margaretha Brongersma-Sanders (1905-1996), Dutch scientist: an annotated bibliography of her work to celebrate 100 years since her birth

    NARCIS (Netherlands)

    Turner, S.; Cadée, G.C.

    2006-01-01

    Dr Margaretha Brongersma-Sanders, palaeontologist, pioneer geochemist, geobiologist and oceanographer, Officer of the Order of Oranje Nassau was born 100 years ago (February 20th, 1905) in Kampen in The Netherlands. The fields of research that she covered during her lifetime include taxonomy of rece

  1. Struggles for Perspective: A Commentary on ""One Story of Many to Be Told": Following Empirical Studies of College and Adult Writing through 100 Years of NCTE Journals"

    Science.gov (United States)

    Brandt, Deborah

    2011-01-01

    In this article, the author comments on Kevin Roozen and Karen Lunsford's insightful examination of empirical studies of college and adult writing published in NCTE journals over the last 100 years. One sees in their account the struggles for perspective that marked writing studies in this period, as researchers applied ever wider lenses to the…

  2. Long term contaminant migration and impacts from uranium mill tailings. Comparison of computer models using a hypothetical dataset

    Energy Technology Data Exchange (ETDEWEB)

    Camus, H. [CEA Centre d' Etudes Nucleaires de Fontenay-aux-Roses (France). Inst. de Protection et de Surete Nucleaire] [and others

    1995-11-01

    and not to represent realistic releases. As such, the results presented do not reflect the actual impact of any real facility. While absolute conclusions about critical pathways etc should not be drawn, a number of useful indicative observations can be made arising from the results comparisons. The V1.07 exercise is essentially a simplified but comprehensive performance assessment of a hypothetical waste disposal facility. The range of results provided using a variety of modelling approaches and models in differing stages of development suggests that it is difficult to exclude from consideration particular contaminants or migration and exposure pathways in advance of detailed assumptions for source terms and other site and assessment specific features. This is consistent with results from an earlier, more generic, BIOMOVS multiple pathway study. Peak impacts on individuals from uranium mill tailings, may not arise for many hundreds of years. Since during this period many possible site and environmental changes might occur, not least because of human actions, a Reference Biosphere approach may be appropriate in developing the scenarios to be modelled for a real site. Reference Biospheres for solid waste disposal assessments are under discussion elsewhere within the BIOMOVS II programme. Methods are available for assessing radiological and non-radiological health risks to individuals from releases from tailings facilities, though their relative significance will be locally dependent. Simplifications to modelling of contaminant accumulation in soil (eg using a 100 year residence time for all contaminants) are probably inappropriate. The long term accumulation potential of the different contaminants may be substantially different. It follows that assumptions have to be made about soil structure and use over the long term. Simplification of the U-238 decay chain, i e assuming Pb-210 and Po-210 are in secular equilibrium with the long-lived parent, Ra-226, is probably not

  3. ERPs reveal sensitivity to hypothetical contexts in spoken discourse.

    Science.gov (United States)

    Dwivedi, Veena D; Drury, John E; Molnar, Monika; Phillips, Natalie A; Baum, Shari; Steinhauer, Karsten

    2010-08-04

    We used event-related potentials to examine the interaction between two dimensions of discourse comprehension: (i) referential dependencies across sentences (e.g. between the pronoun 'it' and its antecedent 'a novel' in: 'John is reading a novel. It ends quite abruptly'), and (ii) the distinction between reference to events/situations and entities/individuals in the real/actual world versus in hypothetical possible worlds. Cross-sentential referential dependencies are disrupted when the antecedent for a pronoun is embedded in a sentence introducing hypothetical entities (e.g. 'John is considering writing a novel. It ends quite abruptly'). An earlier event-related potential reading study showed such disruptions yielded a P600-like frontal positivity. Here we replicate this effect using auditorily presented sentences and discuss the implications for our understanding of discourse-level language processing.

  4. ATOME : a blackboard architecture with temporal and hypothetical reasoning

    OpenAIRE

    Laasri, Hassan; Maitre, Brigitte; Mondot, Thierry; Charpillet, François; Haton, Jean-Paul

    1988-01-01

    To cope with high level AI-based applications as signal understanding, process control or decision making, an AI system must take into account various knowledge sources and reasoning schemes. In this paper, we propose a blackboard-based architecture which achieves opportunism and efficiency while controlling multiple knowledge sources. In addition it integrates temporal and hypothetical reasoning to deal with applications evolving in time, and manipulating noisy or errorfull information.

  5. Correlation-Peak Imaging

    Science.gov (United States)

    Ziegler, A.; Metzler, A.; Köckenberger, W.; Izquierdo, M.; Komor, E.; Haase, A.; Décorps, M.; von Kienlin, M.

    1996-08-01

    Identification and quantitation in conventional1H spectroscopic imagingin vivois often hampered by the small chemical-shift range. To improve the spectral resolution of spectroscopic imaging, homonuclear two-dimensional correlation spectroscopy has been combined with phase encoding of the spatial dimensions. From the theoretical description of the coherence-transfer signal in the Fourier-transform domain, a comprehensive acquisition and processing strategy is presented that includes optimization of the width and the position of the acquisition windows, matched filtering of the signal envelope, and graphical presentation of the cross peak of interest. The procedure has been applied to image the spatial distribution of the correlation peaks from specific spin systems in the hypocotyl of castor bean (Ricinus communis) seedlings. Despite the overlap of many resonances, correlation-peak imaging made it possible to observe a number of proton resonances, such as those of sucrose, β-glucose, glutamine/glutamate, lysine, and arginine.

  6. Processing counterfactual and hypothetical conditionals: an fMRI investigation.

    Science.gov (United States)

    Kulakova, Eugenia; Aichhorn, Markus; Schurz, Matthias; Kronbichler, Martin; Perner, Josef

    2013-05-15

    Counterfactual thinking is ubiquitous in everyday life and an important aspect of cognition and emotion. Although counterfactual thought has been argued to differ from processing factual or hypothetical information, imaging data which elucidate these differences on a neural level are still scarce. We investigated the neural correlates of processing counterfactual sentences under visual and aural presentation. We compared conditionals in subjunctive mood which explicitly contradicted previously presented facts (i.e. counterfactuals) to conditionals framed in indicative mood which did not contradict factual world knowledge and thus conveyed a hypothetical supposition. Our results show activation in right occipital cortex (cuneus) and right basal ganglia (caudate nucleus) during counterfactual sentence processing. Importantly the occipital activation is not only present under visual presentation but also with purely auditory stimulus presentation, precluding a visual processing artifact. Thus our results can be interpreted as reflecting the fact that counterfactual conditionals pragmatically imply the relevance of keeping in mind both factual and supposed information whereas the hypothetical conditionals imply that real world information is irrelevant for processing the conditional and can be omitted. The need to sustain representations of factual and suppositional events during counterfactual sentence processing requires increased mental imagery and integration efforts. Our findings are compatible with predictions based on mental model theory. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. On hypothetical bias and calibration in cost-benefit studies.

    Science.gov (United States)

    Liljas, B; Blumenschein, K

    2000-05-01

    Despite a sound foundation in economic welfare theory, willingness to pay (WTP) has not been used as a measure of benefits in economic evaluations of health and health care to the same extent as in other fields. Some have suggested that this is due to non-economists' reluctance to placing dollar values on the benefits of health care. However, another potential reason could be uncertainties about the validity of the WTP measure. In this paper, we outline the bias problems with the WTP method, and specifically focus on hypothetical bias; i.e. whether the WTP from hypothetical elicitation methods overstates the real WTP or not. This is done by examining the literature in this field, with emphasis on economic experiments where there is a greater possibility for comparison. The findings are that hypothetical WTP in general significantly overestimates real WTP, but that calibration methods to reduce or eliminate this difference are currently being developed. We conclude that while the area is still very much under development, there seem to be reasons to view the use of cost-benefit analysis as a reasonable alternative to the more common cost-effectiveness analysis.

  8. Hypothetical contractarianism and the disclosure requirement problem in informed consent.

    Science.gov (United States)

    Cust, Kenneth F T

    1991-01-01

    Two of the more deeply problematic issues surrounding the doctrine of informed consent are providing a justification for the practice of informed consent and providing an account of the nature and amount of information that must be disclosed in order for informed consent to take place. This paper is concerned with the latter problem, the problem of disclosure requirements, but it deals with this problem in a novel way; it approaches the problem by asking what fully informed and fully rational agents would agree to under certain hypothetical conditions. In general terms I juxtapose the hypothetical contractarianism found in Rawls' A Theory of Justice with that found in Gauthier's Morals By Agreement and ask what their respective hypothetical contractors would agree to with respect to choosing a particular standard of disclosure to govern the practice of informed consent. In more specific terms a contrast is made between what a Rawlsian agent behind a veil of ignorance would choose as compared to what, in Gauthier's terms, an ideal actor making an Archimedean choice would choose. The idea of an Archimedean point, and the subsequent choice made from that point, although technically identified by Rawls, originated with Archimedes of Syracuse.

  9. Structural and Functional Annotation of Hypothetical Proteins of O139

    Directory of Open Access Journals (Sweden)

    Md. Saiful Islam

    2015-06-01

    Full Text Available In developing countries threat of cholera is a significant health concern whenever water purification and sewage disposal systems are inadequate. Vibrio cholerae is one of the responsible bacteria involved in cholera disease. The complete genome sequence of V. cholerae deciphers the presence of various genes and hypothetical proteins whose function are not yet understood. Hence analyzing and annotating the structure and function of hypothetical proteins is important for understanding the V. cholerae. V. cholerae O139 is the most common and pathogenic bacterial strain among various V. cholerae strains. In this study sequence of six hypothetical proteins of V. cholerae O139 has been annotated from NCBI. Various computational tools and databases have been used to determine domain family, protein-protein interaction, solubility of protein, ligand binding sites etc. The three dimensional structure of two proteins were modeled and their ligand binding sites were identified. We have found domains and families of only one protein. The analysis revealed that these proteins might have antibiotic resistance activity, DNA breaking-rejoining activity, integrase enzyme activity, restriction endonuclease, etc. Structural prediction of these proteins and detection of binding sites from this study would indicate a potential target aiding docking studies for therapeutic designing against cholera.

  10. Peak-interviewet

    DEFF Research Database (Denmark)

    Raalskov, Jesper; Warming-Rasmussen, Bent

    Peak-interviewet er en særlig effektiv metode til at gøre ubevidste menneskelige ressourcer bevidste. Fokuspersonen (den interviewede) interviewes om en selvvalgt, personlig succesoplevelse. Terapeuten/coachen (intervieweren) spørger ind til processen, som ledte hen til denne succes. Herved afdæk...

  11. Peak-interviewet

    DEFF Research Database (Denmark)

    Raalskov, Jesper; Warming-Rasmussen, Bent

    Peak-interviewet er en særlig effektiv metode til at gøre ubevidste menneskelige ressourcer bevidste. Fokuspersonen (den interviewede) interviewes om en selvvalgt, personlig succesoplevelse. Terapeuten/coachen (intervieweren) spørger ind til processen, som ledte hen til denne succes. Herved afdæk...

  12. Impact Crater with Peak

    Science.gov (United States)

    2002-01-01

    (Released 14 June 2002) The Science This THEMIS visible image shows a classic example of a martian impact crater with a central peak. Central peaks are common in large, fresh craters on both Mars and the Moon. This peak formed during the extremely high-energy impact cratering event. In many martian craters the central peak has been either eroded or buried by later sedimentary processes, so the presence of a peak in this crater indicates that the crater is relatively young and has experienced little degradation. Observations of large craters on the Earth and the Moon, as well as computer modeling of the impact process, show that the central peak contains material brought from deep beneath the surface. The material exposed in these peaks will provide an excellent opportunity to study the composition of the martian interior using THEMIS multi-spectral infrared observations. The ejecta material around the crater can is well preserved, again indicating relatively little modification of this landform since its initial creation. The inner walls of this approximately 18 km diameter crater show complex slumping that likely occurred during the impact event. Since that time there has been some downslope movement of material to form the small chutes and gullies that can be seen on the inner crater wall. Small (50-100 m) mega-ripples composed of mobile material can be seen on the floor of the crater. Much of this material may have come from the walls of the crater itself, or may have been blown into the crater by the wind. The Story When a meteor smacked into the surface of Mars with extremely high energy, pow! Not only did it punch an 11-mile-wide crater in the smoother terrain, it created a central peak in the middle of the crater. This peak forms kind of on the 'rebound.' You can see this same effect if you drop a single drop of milk into a glass of milk. With craters, in the heat and fury of the impact, some of the land material can even liquefy. Central peaks like the one

  13. Demand Curves for Hypothetical Cocaine in Cocaine-Dependent Individuals

    Science.gov (United States)

    Bruner, Natalie R.; Johnson, Matthew W.

    2013-01-01

    Rationale Drug purchasing tasks have been successfully used to examine demand for hypothetical consumption of abused drugs including heroin, nicotine, and alcohol. In these tasks drug users make hypothetical choices whether to buy drugs, and if so, at what quantity, at various potential prices. These tasks allow for behavioral economic assessment of that drug's intensity of demand (preferred level of consumption at extremely low prices) and demand elasticity (sensitivity of consumption to price), among other metrics. However, a purchasing task for cocaine in cocaine-dependent individuals has not been investigated. Objectives This study examined a novel Cocaine Purchasing Task and the relation between resulting demand metrics and self-reported cocaine use data. Methods Participants completed a questionnaire assessing hypothetical purchases of cocaine units at prices ranging from $0.01 to $1,000. Demand curves were generated from responses on the Cocaine Purchasing Task. Correlations compared metrics from the demand curve to measures of real-world cocaine use. Results Group and individual data were well modeled by a demand curve function. The validity of the Cocaine Purchasing Task was supported by a significant correlation between the demand curve metrics of demand intensity and Omax (determined from Cocaine Purchasing Task data) and self-reported measures of cocaine use. Partial correlations revealed that after controlling for demand intensity, demand elasticity and the related measure, Pmax, were significantly correlated with real-world cocaine use. Conclusions Results indicate that the Cocaine Purchasing Task produces orderly demand curve data, and that these data relate to real-world measures of cocaine use. PMID:24217899

  14. Demand curves for hypothetical cocaine in cocaine-dependent individuals.

    Science.gov (United States)

    Bruner, Natalie R; Johnson, Matthew W

    2014-03-01

    Drug purchasing tasks have been successfully used to examine demand for hypothetical consumption of abused drugs including heroin, nicotine, and alcohol. In these tasks, drug users make hypothetical choices whether to buy drugs, and if so, at what quantity, at various potential prices. These tasks allow for behavioral economic assessment of that drug's intensity of demand (preferred level of consumption at extremely low prices) and demand elasticity (sensitivity of consumption to price), among other metrics. However, a purchasing task for cocaine in cocaine-dependent individuals has not been investigated. This study examined a novel Cocaine Purchasing Task and the relation between resulting demand metrics and self-reported cocaine use data. Participants completed a questionnaire assessing hypothetical purchases of cocaine units at prices ranging from $0.01 to $1,000. Demand curves were generated from responses on the Cocaine Purchasing Task. Correlations compared metrics from the demand curve to measures of real-world cocaine use. Group and individual data were well modeled by a demand curve function. The validity of the Cocaine Purchasing Task was supported by a significant correlation between the demand curve metrics of demand intensity and O max (determined from Cocaine Purchasing Task data) and self-reported measures of cocaine use. Partial correlations revealed that after controlling for demand intensity, demand elasticity and the related measure, P max, were significantly correlated with real-world cocaine use. Results indicate that the Cocaine Purchasing Task produces orderly demand curve data, and that these data relate to real-world measures of cocaine use.

  15. Constraints on hypothetical counterexamples to the Casas-Alvero conjecture

    CERN Document Server

    Laterveer, Robert

    2012-01-01

    The Casas-Alvero conjecture states: if a complex univariate polynomial has a common root with each of its derivatives, then it has a unique root. We show that hypothetical counterexamples must have at least 5 different roots. The first case where the conjecture is not known is in degree 12. We study the case of degree 12, and more generally degree p+1, where p is a prime number. While we don't come closing to solving the conjecture in degree 12, we present several further constraints that counterexamples would have to satisfy.

  16. Search for the hypothetical $\\pi$ -> $\\mu$ + x decay

    CERN Document Server

    Bilger, R; Denig, A; Föhl, K; Hautle, P; Kluge, W; Konter, J A; Kurz, G; Mango, S; Schapler, D; Schonleber, F; Siodlaczek, U; Van den Brandt, B; Wagner, G J; Wieser, R

    1995-01-01

    The KARMEN collaboration has reported the possible observation of a hitherto unknown neutral and weakly interacting particle x, which is produced in the decay pi -> mu + x with a mass m(x) = 33.9 MeV. We have searched for this hypothetical decay branch by studying muons from pion decay in flight with the LEPS spectrometer at the piE3 channel at PSI and find branching ratios BR(pi- to mu- anti-x) 2e-8 derived in a recent theoretical paper our result would leave only a narrow region for the existence of x if it is a heavy neutrino.

  17. Consequences of a hypothetical incident for different sectors

    CERN Document Server

    Bertinelli, F; Garion, C; Jimenez, J M; Parma, V; Perin, A; Schmidt, R; Tavian, L; Tock, J P; van Weelderen, R

    2011-01-01

    During the 2009 long shutdown, the LHC machine has been partially consolidated by adding safety relief devices in order to better protect the cryostats against large helium release and consequently to mitigate the risks of collateral damages. After recalling the present relief valve implementation and other mitigations related to the collateral damages, this paper describes the damage process of a hypothetical incident, presents its consequences for the different sectors and for beam energies up to 5 TeV with emphasis on the induced downtime.

  18. Estimating Potential Effects of Hypothetical Oil Spills on Polar Bears

    Science.gov (United States)

    Amstrup, Steven C.; Durner, G.M.; McDonald, T.L.; Johnson, W.R.

    2006-01-01

    Much is known about the transport and fate of oil spilled into the sea and its toxicity to exposed wildlife. Previously, however, there has been no way to quantify the probability that wildlife dispersed over the seascape would be exposed to spilled oil. Polar bears, the apical predator of the arctic, are widely dispersed near the continental shelves of the Arctic Ocean, an area also undergoing considerable hydrocarbon exploration and development. We used 15,308 satellite locations from 194 radiocollared polar bears to estimate the probability that polar bears could be exposed to hypothetical oil spills. We used a true 2 dimensional Gausian kernel density estimator, to estimate the number of bears likely to occur in each 1.00 km2 cell of a grid superimposed over near shore areas surrounding 2 oil production facilities: the existing Northstar oil production facility, and the proposed offshore site for the Liberty production facility. We estimated the standard errors of bear numbers per cell with bootstrapping. Simulated oil spill footprints for September and October, the times during which we hypothesized effects of an oil-spill would be worst, were estimated using real wind and current data collected between 1980 and 1996. We used ARC/Info software to calculate overlap (numbers of bears oiled) between simulated oil-spill footprints and polar bear grid-cell values. Numbers of bears potentially oiled by a hypothetical 5912 barrel spill (the largest spill thought probable from a pipeline breach) ranged from 0 to 27 polar bears for September open water conditions, and from 0 to 74 polar bears in October mixed ice conditions. Median numbers oiled by the 5912 barrel hypothetical spill from the Liberty simulation in September and October were 1 and 3 bears, equivalent values for the Northstar simulation were 3 and 11 bears. In October, 75% of trajectories from the 5912 barrel simulated spill at Liberty oiled 9 or fewer bears while 75% of the trajectories affected 20 or

  19. Effects of hypothetical improvised nuclear detonation on the electrical infrastructure

    Energy Technology Data Exchange (ETDEWEB)

    Barrett, Christopher L.; Eubank, Stephen; Evrenosoglu, C. Yaman; Marathe, Achla; Marathe, Madhav V.; Phadke, Arun; Thorp, James; Vullikanti, Anil [Virginia Tech, Blacksburg, VA (United States). Network Dynamics and Simulation Science Lab.

    2013-07-01

    We study the impacts of a hypothetical improvised nuclear detonation (IND) on the electrical infrastructure and its cascading effects on other urban inter-dependent infrastructures of a major metropolitan area in the US. We synthesize open source information, expert knowledge, commercial software and Google Earth data to derive a realistic electrical transmission and distribution network spanning the region. A dynamic analysis of the geo-located grid is carried out to determine the cause of malfunction of components, and their short-term and long-term effect on the stability of the grid. Finally a detailed estimate of the cost of damage to the major components of the infrastructure is provided.

  20. 100 years of Planck's quantum

    CERN Document Server

    Duck, Ian M

    2000-01-01

    This invaluable book takes the reader from Planck's discovery of the quantum in 1900 to the most recent interpretations and applications of nonrelativistic quantum mechanics.The introduction of the quantum idea leads off the prehistory of quantum mechanics, featuring Planck, Einstein, Bohr, Compton, and de Broglie's immortal contributions. Their original discovery papers are featured with explanatory notes and developments in Part 1.The invention of matrix mechanics and quantum mechanics by Heisenberg, Born, Jordan, Dirac, and Schrödinger is presented next, in Part 2.Following that, in Part 3,

  1. 100 Years of Chinese Education

    Institute of Scientific and Technical Information of China (English)

    ZHANG ZHIPING

    2010-01-01

    @@ This year marks the 100th anniversary of the foundation of the Department of Chinese Language and Literature (DOCLL) of Peking University. On March 31, 1910, the Imperial Capital University (the predecessor of today's Peking University) was estab-lished, with a Chinese literature school as an independent teaching unit.

  2. 100 Years of Chinese Education

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    This year marks the 100th anniversary of the foundation of the Department of Chinese Language and Literature (DOCLL) of Peking University. On March 31,1910,the Imperial Capital University (the predecessor of today’s Peking University) was established,with a Chinese literature school as an independent teaching unit.

  3. 100 years of Philips Research

    Science.gov (United States)

    van Delft, Dirk

    2014-03-01

    On Thursday 23 October 1913, a Dutch newspaper published the following advertisement: Hiring: A capable young scientist with a doctorate in physics. Must be a good experimenter. Letters containing information on age, life history and references may be submitted to Philips in Eindhoven. Two days later, a candidate applied: Gilles Holst. At that time, Holst was working in Leiden as an assistant to Heike Kamerlingh Onnes, a recent Nobel Prize winner.

  4. 100 years of radionuclide metrology.

    Science.gov (United States)

    Judge, S M; Arnold, D; Chauvenet, B; Collé, R; De Felice, P; García-Toraño, E; Wätjen, U

    2014-05-01

    The discipline of radionuclide metrology at national standards institutes started in 1913 with the certification by Curie, Rutherford and Meyer of the first primary standards of radium. In early years, radium was a valuable commodity and the aim of the standards was largely to facilitate trade. The focus later changed to providing standards for the new wide range of radionuclides, so that radioactivity could be used for healthcare and industrial applications while minimising the risk to patients, workers and the environment. National measurement institutes responded to the changing demands by developing new techniques for realising primary standards of radioactivity. Looking ahead, there are likely to be demands for standards for new radionuclides used in nuclear medicine, an expansion of the scope of the field into quantitative imaging to facilitate accurate patient dosimetry for nuclear medicine, and an increasing need for accurate standards for radioactive waste management and nuclear forensics.

  5. FEMA 100 year Flood Data

    Data.gov (United States)

    California Department of Resources — The Q3 Flood Data product is a digital representation of certain features of FEMA's Flood Insurance Rate Map (FIRM) product, intended for use with desktop mapping...

  6. Elusive but not hypothetical: axillary meristems in Wollemia nobilis.

    Science.gov (United States)

    Burrows, Geoffrey E

    2012-01-01

    The branches of Wollemia nobilis are unbranched; however, it has been noted that new branches can form from the distal end of damaged ones, and branches can grow from axillary structures once a terminal strobilus has fallen. Tomlinson and Huggett (2011, Annals of Botany 107: 909-916) have recently investigated the formation of these reiterative branches and stated in the title of their paper that 'Partial shoot reiteration in Wollemia nobilis (Araucariaceae) does not arise from "axillary meristems"'. They go on to state 'Further research may reveal the presence of these elusive, but still only hypothetical, axillary meristems'. In this Viewpoint, I argue that Tomlinson and Huggett do not refer to previously published information that indicates that axillary meristems are present in Wollemia nobilis branch leaf axils, and that their anatomical methods were probably not optimal for locating and examining these minute structures. Thus, whilst I would agree that the axillary meristems in branch leaf axils of Wollemia nobilis are elusive, I contend that they are not hypothetical.

  7. On the hypothetical utilization of atmospheric potential energy

    Directory of Open Access Journals (Sweden)

    Thomas Frisius

    2014-09-01

    Full Text Available Atmospheric potential energy is typically divided into an available and a nonavailable part. In this article a hypothetical utilization of a fraction of the nonavailable potential energy is described. This part stems from the water vapor that can be converted into the liquid phase. An energy gain results when the potential energy of the condensate relative to a reference height exceeds the energy necessary to condensate the water vapor. It is shown that this can be the case in a saturated atmosphere without convective available potential energy. Finally, simulations with the numerical cloud model HURMOD are performed to estimate the usability of the device in practice. Indeed, a positive energy output results in a simulation with immediate gathering of the condensate. On the contrary, potential energy gained falls significantly short of the necessary energy for forming the condensate when a realistic cloud microphysical scheme allowing re-evaporation of condensate is applied. Taken together it can be concluded that, a utilization of atmospheric potential energy is hypothetically possible but the practical realization is probably not feasible.

  8. Further tests of entreaties to avoid hypothetical bias in referendum contingent valuation

    Science.gov (United States)

    Thomas C. Brown; Icek Ajzen; Daniel Hrubes

    2003-01-01

    Over-estimation of willingness to pay in contingent markets has been attributed largely to hypothetical bias. One promising approach for avoiding hypothetical bias is to tell respondents enough about such bias that they self-correct for it. A script designed for this purpose by Cummings and Taylor was used in hypothetical referenda that differed in payment amount. In...

  9. Geyser Peak Cabernet Sauvignon

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    <正>年份:2000产地:美国加州Sonoma County售价:$196 Geyser Peak(盖世峰)成立于1880年,是美国军有的过百岁葡萄酒庄。可惜美国酿制葡萄酒的技术在近三四十年才有突破,历史再悠久也没有太多帮助近二十年Geyser Peak就努力改进,希望迎头赶上其它加州新秀的水平,1989年,他们就聘请了澳洲Penfolds酒庄的酿酒师Daryl Groom,让旗下出品多了一份澳洲式的"霎眼娇"风格。2003年,Geyser Peak更在International Wine & Spirit Competition赢得"最佳美国葡萄酒生产商"大奖。

  10. History of views on the relative positions of Antarctica and South America: A 100-year tango between Patagonia and the Antarctic Peninsula

    Science.gov (United States)

    Miller, H.

    2007-01-01

    Discussion of continental drift around Antarctica began nearly 100 years ago. While the Gondwana connections of Antarctica to Africa and Australia have been well defined for decades, the relative pre-drift positions of the Antarctic Peninsula and Patagonia continue to be subjects of controversy. Certainly older figures, which showed a paleo-position of the Peninsula crossing over continental crust of the Falkland Plateau or even South Africa or Patagonia, are out of consideration now. But contradictory opinions remain over the relative paleo-position of the Peninsula as a more or less straight prolongation of the Patagonian Andes, versus a position parallel to Patagonia along the Pacific coast. Geological reasons are found for both opinions, but geophysical observations on the adjacent ocean floors, particularly the evolution of the Weddell Sea crust, speak for the last-mentioned reconstruction.

  11. CoSMoS Southern California v3.0 Phase 1 (100-year storm) flood hazard projections: Los Angeles, San Diego and Orange counties

    Science.gov (United States)

    Barnard, Patrick; Erikson, Li; Foxgrover, Amy; O'Neill, Andrea; Herdman, Liv

    2015-01-01

    The Coastal Storm Modeling System (CoSMoS) makes detailed predictions (meter-scale) over large geographic scales (100s of kilometers) of storm-induced coastal flooding and erosion for both current and future sea-level rise (SLR) scenarios. CoSMoS v3.0 for Southern California shows projections for future climate scenarios (sea-level rise and storms) to provide emergency responders and coastal planners with critical storm-hazards information that can be used to increase public safety, mitigate physical damages, and more effectively manage and allocate resources within complex coastal settings. Phase I data for Southern California include flood-hazard information for the coast from the Mexican Border to Pt. Conception for a 100-year storm scenario. Data are complete for the information presented but are considered preliminary; changes may be reflected in the full data release (Phase II) in summer 2016.

  12. 还原染料百年发展史话(待续)%The development of vat dyes in 100 years(to be continued)

    Institute of Scientific and Technical Information of China (English)

    陈荣圻

    2015-01-01

    1901年,BASF合成并生产了第1只还原染料(还原染料RSN),距今超过一百年,如果说1987年合成靛蓝早已诞生于BASF,那离百年就更远了.还原染料化学结构复杂,合成过程冗长、三废量大、难于处理,所以价格昂贵.但因其色彩鲜艳、密度高,非其他棉用染料所能取代.还原染料除了印染,经颜料化后,某些染料可制得高档有机颜料,有些品种还能拓展到光物理、电化学领域的液晶、光导材料等高科技领域,是不可缺失的功能材料,旧貌换新颜.%The first vat dye (vat dye RSN) was synthesized and produced by BASF in 1901, which was more than 100 years. Considering indigo blue was synthesized by BASF in 1987, it has a history of far more than 100 years. Vat dyes are expensive because of its complex chemical structure and long synthesis process with large amount of "three wastes" that are difficult to deal with. However, vat dyes are colourful, high color density and impossible to be replaced by any other dyes. Besides printing and dyeing, vat dyes can obtain high-grade organic pigments after pigmentation. Some of those high-grade organic pigments can extend to optical physics, liquid crystal in the electrochemistry optical material fields and other high-tech fields, which are indispensable function materials and completely changed.

  13. Effects of 100 years wastewater irrigation on resistance genes, class 1 integrons and IncP-1 plasmids in Mexican soil

    Directory of Open Access Journals (Sweden)

    Sven eJechalke

    2015-03-01

    Full Text Available Long-term irrigation with untreated wastewater can lead to an accumulation of antibiotic substances and antibiotic resistance genes in soil. However, little is known so far about effects of wastewater, applied for decades, on the abundance of IncP-1 plasmids and class 1 integrons which may contribute to the accumulation and spread of resistance genes in the environment, and their correlation with heavy metal concentrations.Therefore, a chronosequence of soils that were irrigated with wastewater from zero to 100 years was sampled in the Mezquital Valley in Mexico in the dry season. The total community DNA was extracted and the absolute and relative abundance (relative to 16S rRNA genes of antibiotic resistance genes (tet(W, tet(Q, aadA, class 1 integrons (intI1, quaternary ammonium compound resistance genes (qacE+qacEΔ1 and IncP-1 plasmids (korB were quantified by real-time PCR. Except for intI1 and qacE+qacEΔ1 the abundances of selected genes were below the detection limit in non-irrigated soil. Confirming the results of a previous study, the absolute abundance of 16S rRNA genes in the samples increased significantly over time (linear regression model, p < 0.05 suggesting an increase in bacterial biomass due to repeated irrigation with wastewater. Correspondingly, all tested antibiotic resistance genes as well as intI1 and korB significantly increased in abundance over the period of 100 years of irrigation. In parallel, concentrations of the heavy metals Zn, Cu, Pb, Ni, and Cr significantly increased. However, no significant positive correlations were observed between the relative abundance of selected genes and years of irrigation, indicating no enrichment in the soil bacterial community due to repeated wastewater irrigation or due to a potential co-selection by increasing concentrations of heavy metals.

  14. Reconstruction of soil moisture for the past 100 years in eastern Siberia by using δ13C of larch tree rings

    Science.gov (United States)

    Tei, Shunsuke; Sugimoto, Atsuko; Yonenobu, Hitoshi; Yamazaki, Takeshi; Maximov, Trofim C.

    2013-07-01

    stable carbon isotope ratio (δ13C) chronology for the past 100 years was developed from larch tree rings in eastern Siberia (near Yakutsk, 62°14'N, 129°37'E), to reconstruct past soil moisture water equivalent (SWE). Based on the correlation analyses between SWE and tree ring δ13C, we developed a linear regression model for SWE in the late growing period (LGP: 15 July to 31 August) using annual tree ring δ13C, which was calculated from the combination of latewood in a current year and earlywood in the following year, and then reconstructed SWE (LGP) for 1908-2007. Reconstructed SWE was compared with factors such as the output of the land surface model, annual precipitation, and Palmer Drought Severity Index for July. From the results, the reconstructed SWE appears reasonable and shows a large variation, including repeated occurrences of severe drought and an unprecedented high soil moisture event in 2006-2007 during the past 100 years. The reconstruction also captured a past documented record of severe drought in the 1940s. Despite the generally good performance of the reconstruction, by the 1930s the estimated SWE was higher than that expected from the annual precipitation. Tree ring width and δ13C were negatively correlated in most periods. However, the negative correlation was weaker for the period from 1919 to 1925, when relatively low air temperature was observed. This result suggests that the rate of photosynthesis, together with the degree of stomata opening, also affected the tree ring δ13C during cool periods.

  15. Changes in C37 alkenones flux on the eastern continental shelf of the Bering Sea: the record of Emiliania huxleyi bloom over the past 100 years

    Science.gov (United States)

    Harada, N.; Sato, M.; Okazaki, Y.; Oguri, K.; Tadai, O.; Saito, S.; Konno, S.; Jordan, R. W.; Katsuki, K.; Shin, K.; Narita, H.

    2008-12-01

    Flourishes of coccolithophores can be detected by ocean color imagery with data from the satellite-borne Sea-viewing Wide Field-of-view sensor SeaWiFs that was launched in 1997. Thus, temporally and spatially large-scale blooms of Emiliania huxleyi (E. huxleyi) have been distinguished annually in the eastern continental shelf of the Bering Sea since 1997. In 1997, a combination of atmospheric mechanisms produced summer weather anomalies such as calm winds, clear skies, and warm air temperature over the Bering Sea and the weather anomalies caused depletion of the subpycnocline nutrient reservoir (Napp and Hunt, 2001). After depletion of nitrate and silicate, a sustained (more than 4-month-long) bloom of E. huxleyi was observed (Stockwell et al., 2001). Because of the speed and magnitude with which parts of the Bering Sea ecosystem responded to changes in atmospheric factors (Napp and Hunt, 2001) and because a bloom of the coccolithophorid, Coccolithus pelagicus has also been detected in the northeastern Atlantic Ocean off Iceland every year since 1997 (Ostermann, 2001), the appearance of an E. huxleyi bloom in the Bering Sea could be related to atmospherically forced decadal oscillations or global factors. We have investigated spatial expansion and temporal development of E. huxleyi bloom on the continental shelf in the Bering Sea by using a biomarker of E. huxleyi, C37 alkenones flux recorded in the sediments during the past 100 years. As a result, the E. huxleyi bloom had been prominent since 1970"fs at latest during the last 100 years. In this presentation, we will discuss the relationship between E. huxleyi bloom and activity of Aleutian low, and also changes in diatom assemblages. References Napp and Hunt, 2001, Fish Oceanogr., 10, 61-68. Ostermann, 2001, WHOI annual report, pp.17-18. Stockwell et al., 2001, Fish Oceanogr., 10, 99-116.

  16. A Theory on the Ventilation over Hypothetical Urban Areas

    Science.gov (United States)

    Liu, Chun-Ho; Ng, Chi-To; Wong, Colman C. C.

    2013-04-01

    Urban roughness is one of the major factors affecting the flows and turbulence structures in the bottom of the atmospheric boundary layer (ABL). Whereas, our understanding of their relation is limited. In this paper, we attempt to examine the interaction among aerodynamic resistance (friction factor f), ventilation (air exchange rate ACH), and pollutant removal (pollutant removal rate PCH). Using the method of characteristic, analytical solution shows that the turbulent ventilation of a hypothetical urban area is directly proportional to the square root of friction factor (ACH? f1-2) regardless of the building geometry. Next, a series of computational fluid dynamics (CFD) sensitivity tests are performed to verify the theory. In addition to the commonly employed rectangular building models, seven types of urban roughness elements, in the form of idealized building models, are tested. As a pilot study, the building models are of the same height so a roof level is easily defined across the entire hypothetical urban areas. Two configurations of passive scalar sources, ground-level-only (vehicular emission) and all-solid-boundary (heat dissipation), are employed to contrast their transport behaviors. To look into the mechanism of ventilation and pollutant removal, the ACH and PCH are partitioned into their respective mean and turbulent components. The CFD results show that both the ventilation and pollutant removal are mainly attributed to their turbulent components (over 60%). Moreover, the ACH″ and f1-2 calculation from the CFD results agree very well with the analytical solution (correlation coefficient over 0.9). However, the pollutant and heat exhibit different removal behaviors so simple estimates using friction factor have not yet arrived. Because of the substantial aged air removal by ACH″ and its linear relation with f1-2, it is proposed to use friction factor, which can be determined by wind tunnel experiments or mathematical modeling, as a

  17. Radiological Consequence Analyses Following a Hypothetical Severe Accident in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Juyub; Kim, Juyoul [FNC Technology Co., Yongin (Korea, Republic of)

    2016-10-15

    In order to reflect the lessons learned from the Fukushima Daiichi nuclear power plant accident, a simulator which is named NANAS (Northeast Asia Nuclear Accident Simulator) for overseas nuclear accident has been developed. It is composed of three modules: source-term estimation, atmospheric dispersion prediction and dose assessment. For the source-term estimation module, the representative reactor types were selected as CPR1000, BWR5 and BWR6 for China, Japan and Taiwan, respectively. Considering the design characteristics of each reactor type, the source-term estimation module simulates the transient of design basis accident and severe accident. The atmospheric dispersion prediction module analyzes the transport and dispersion of radioactive materials and prints out the air and ground concentration. Using the concentration result, the dose assessment module calculates effective dose and thyroid dose in the Korean Peninsula region. In this study, a hypothetical severe accident in Japan was simulated to demonstrate the function of NANAS. As a result, the radiological consequence to Korea was estimated from the accident. PC-based nuclear accident simulator, NANAS, has been developed. NANAS contains three modules: source-term estimation, atmospheric dispersion prediction and dose assessment. The source-term estimation module simulates a nuclear accident for the representative reactor types in China, Japan and Taiwan. Since the maximum calculation speed is 16 times than real time, it is possible to estimate the source-term release swiftly in case of the emergency. The atmospheric dispersion prediction module analyzes the transport and dispersion of radioactive materials in wide range including the Northeast Asia. Final results of the dose assessment module are a map projection and time chart of effective dose and thyroid dose. A hypothetical accident in Japan was simulated by NANAS. The radioactive materials were released during the first 24 hours and the source

  18. Peak mass and dynamical friction

    CERN Document Server

    Del Popolo, A

    1995-01-01

    We show how the results given by several authors relatively to the mass of a density peak are changed when small scale substructure induced by dynamical friction are taken into account. The peak mass obtained is compared to the result of Peacock \\& Heavens (1990) and to the peak mass when dynamical friction is absent to show how these effects conspire to reduce the mass accreted by the peak.

  19. Peak capacity in unidimensional chromatography.

    Science.gov (United States)

    Neue, Uwe Dieter

    2008-03-14

    The currently existing knowledge about peak capacity in unidimensional separations is reviewed. The majority of the paper is dedicated to reversed-phase gradient chromatography, covering specific techniques as well as the subject of peak compression. Other sections deal with peak capacity in isocratic chromatography, size-exclusion chromatography and ion-exchange chromatography. An important topic is the limitation of the separation power and the meaning of the concept of peak capacity for real applications.

  20. Disability and marginal utility of income: evidence from hypothetical choices.

    Science.gov (United States)

    Tengstam, Sven

    2014-03-01

    It is often assumed that disability reduces the marginal utility of income. In this article, individuals' marginal utility of income in two states-(i) paralyzed in both legs from birth and (ii) not mobility impaired at all-is measured through hypothetical choices between imagined lotteries behind a so-called veil of ignorance. The outcomes of the lotteries include both income and disability status. It is found that most people have higher marginal utility when paralyzed than when not mobility impaired at all. The two marginal utilities are evaluated at the same levels of income. Having personal experience of mobility impairment and supporting the Left Party, the Social Democratic Party, the Green Party, or the Liberal Party are associated with having a higher marginal utility when paralyzed. The results suggest that more than full insurance of income losses connected to being disabled is optimal. The results further suggest that, given a utilitarian social welfare function, resources should be transferred to rather than from disabled people. Finally, if the transfers are not large enough to smooth out the marginal utilities of the disabled and the nondisabled, distributional weights based on disability status should be used in cost-benefit analysis.

  1. Comprehensive computerized medical imaging: interim hypothetical economic evaluation

    Science.gov (United States)

    Warburton, Rebecca N.; Fisher, Paul D.; Nosil, Josip

    1990-08-01

    The 422-bed Victoria General Hospital (VGH) and Siemens Electric Limited have since 1983 been piloting the implementation of comprehensive computerized medical imaging, including digital acquisition of diagnostic images, in British Columbia. Although full PACS is not yet in place at VGH, experience to date habeen used to project annual cost figures (including capital replacement) for a fully-computerized department. The resulting economic evaluation has been labelled hypothetical to emphasize that some key cost components were estimated rather than observed; this paper presents updated cost figures based on recent revisions to proposed departmental equipment configuration which raised the cost of conventional imaging equipment by 0.3 million* and lowered the cost of computerized imaging equipment by 0.8 million. Compared with conventional diagnostic imaging, computerized imaging appears to raise overall annual costs at VGH by nearly 0.7 million, or 11.6%; this is more favourable than the previous results, which indicated extra annual costs of 1 million (16.9%). Sensitivity analysis still indicates that all reasonable changes in the underlying assumptions result in higher costs for computerized imaging than for conventional imaging. Computerized imaging offers lower radiation exposure to patients, shorter waiting times, and other potential advantages, but as yet the price of obtaining these benefits remains substantial.

  2. Large-scale screening of hypothetical metal-organic frameworks

    Science.gov (United States)

    Wilmer, Christopher E.; Leaf, Michael; Lee, Chang Yeon; Farha, Omar K.; Hauser, Brad G.; Hupp, Joseph T.; Snurr, Randall Q.

    2012-02-01

    Metal-organic frameworks (MOFs) are porous materials constructed from modular molecular building blocks, typically metal clusters and organic linkers. These can, in principle, be assembled to form an almost unlimited number of MOFs, yet materials reported to date represent only a tiny fraction of the possible combinations. Here, we demonstrate a computational approach to generate all conceivable MOFs from a given chemical library of building blocks (based on the structures of known MOFs) and rapidly screen them to find the best candidates for a specific application. From a library of 102 building blocks we generated 137,953 hypothetical MOFs and for each one calculated the pore-size distribution, surface area and methane-storage capacity. We identified over 300 MOFs with a predicted methane-storage capacity better than that of any known material, and this approach also revealed structure-property relationships. Methyl-functionalized MOFs were frequently top performers, so we selected one such promising MOF and experimentally confirmed its predicted capacity.

  3. Large-scale screening of hypothetical metal-organic frameworks.

    Science.gov (United States)

    Wilmer, Christopher E; Leaf, Michael; Lee, Chang Yeon; Farha, Omar K; Hauser, Brad G; Hupp, Joseph T; Snurr, Randall Q

    2011-11-06

    Metal-organic frameworks (MOFs) are porous materials constructed from modular molecular building blocks, typically metal clusters and organic linkers. These can, in principle, be assembled to form an almost unlimited number of MOFs, yet materials reported to date represent only a tiny fraction of the possible combinations. Here, we demonstrate a computational approach to generate all conceivable MOFs from a given chemical library of building blocks (based on the structures of known MOFs) and rapidly screen them to find the best candidates for a specific application. From a library of 102 building blocks we generated 137,953 hypothetical MOFs and for each one calculated the pore-size distribution, surface area and methane-storage capacity. We identified over 300 MOFs with a predicted methane-storage capacity better than that of any known material, and this approach also revealed structure-property relationships. Methyl-functionalized MOFs were frequently top performers, so we selected one such promising MOF and experimentally confirmed its predicted capacity.

  4. A 100-Year Retrospective Landscape-Level Carbon Budget for the Sooke Lake Watershed, British Columbia: Constraining Estimates of Terrestrial to Aquatic DOC Transfers.

    Science.gov (United States)

    Trofymow, J. A.; Smiley, B. P. K.

    2014-12-01

    To address how natural disturbance, forest harvest, and deforestation from reservoir creation affect landscape-level carbon (C) budgets, a retrospective C budget for the 8500 ha Sooke watershed from 1911 - 2012 was developed using historic spatial inventory and disturbance data. Data was input to a spatially-explicit version of the Carbon Budget Model-Canadian Forest Sector (CBM-CFS3), an inventory-based C budget model used to simulate forest C dynamics at multiple scales. In 1911 the watershed was dominated by mature/old Douglas-fir forests with aboveground biomass C (ABC) of 262 Mg C/ha and net ecosystem production (NEP) of 0.63 Mg C/ha/yr. Land was cleared around Sooke Lake, a dam built and lake expanded from 370 to 450 ha in 1915, 610 ha in 1970, 670 ha in 1980 and 810 ha in 2002. Along with deforestation, fires and localized harvest occurred from 1920 - 1940, reducing ABC to 189 Mg C/ha, with NEP varying from -1.63 to 0.13 Mg C/ha/yr. Distributed harvest occurred 1954 - 1998, with a minimum ABC of 148 Mg C/ha in 1991. By 2012 ABC (177 Mg C/ha) and NEP (2.29 Mg C/ha/yr) had increased. Over 100 years, 2430 ha forest was cut and replanted and 640 ha deforested. CBM-CFS3 includes transfers of dissolved organic C (DOC) to aquatic systems, however data has not been available to parameterize DOC flux. DOC fluxes are modelled as a fraction of decay loss from humified soil C with a default of 100% of losses to CO2 and 0% to DOC. Stream flow and [DOC] data from 1996 - 2012 for 3 watershed catchments, Rithet, Judge and Council were used to estimate annual DOC fluxes. Rithet, Judge and Council differed both in area % disturbed (logging or fire) over 100 years (39%, 93%, 91%) and in area % mature/old forest (>80yrs in 2012) (67%, 56%, 21%). DOC flux for Rithet and Judge ranged from 0.037 - 0.057 Mg C/ha/yr, Council averaged 0.017 Mg C/ha/yr. Low DOC fluxes were likely due to influences of a small lake in the catchment. Constraining CBM-CFS3 to observed DOC fluxes, required

  5. Spacecraft Mission Design for the Mitigation of the 2017 PDC Hypothetical Asteroid Threat

    Science.gov (United States)

    Barbee, Brent W.; Sarli, Bruno V.; Lyzhoft, Josh; Chodas, Paul W.; Englander, Jacob A.

    2017-01-01

    This paper presents a detailed mission design analysis results for the 2017 Planetary Defense Conference (PDC) Hypothetical Asteroid Impact Scenario, documented at https:cneos.jpl.nasa.govpdcspdc17. The mission design includes campaigns for both reconnaissance (flyby or rendezvous) of the asteroid (to characterize it and the nature of the threat it poses to Earth) and mitigation of the asteroid, via kinetic impactor deflection, nuclear explosive device (NED) deflection, or NED disruption. Relevant scenario parameters are varied to assess the sensitivity of the design outcome, such as asteroid bulk density, asteroid diameter, momentum enhancement factor, spacecraft launch vehicle, and mitigation system type. Different trajectory types are evaluated in the mission design process from purely ballistic to those involving optimal midcourse maneuvers, planetary gravity assists, and/or low-thrust solar electric propulsion. The trajectory optimization is targeted around peak deflection points that were found through a novel linear numerical technique method. The optimization process includes constrain parameters, such as Earth departure date, launch declination, spacecraft, asteroid relative velocity and solar phase angle, spacecraft dry mass, minimum/maximum spacecraft distances from Sun and Earth, and Earth-spacecraft communications line of sight. Results show that one of the best options for the 2017 PDC deflection is solar electric propelled rendezvous mission with a single spacecraft using NED for the deflection.

  6. A centennial to celebrate : energy and minerals science and technology 100 years of excellence : improving the quality of life of Canadians through natural resources

    Energy Technology Data Exchange (ETDEWEB)

    Udd, J.; Reeve, D.

    2007-07-01

    The year 2007 marked the 100th anniversary of Natural Resources Canada's (NRCan) contribution to science and technology excellence in energy and minerals. This publication discussed the 100 years of excellence of the energy and minerals science and technology sector. It discussed the history of Natural Resources Canada, with reference to the early years; first fuel testing efforts; first World War; the 1920s and 1930s; second World War; post-war years; the 1970s and 1980s; and the 1990s to the present. The publication discussed the creation of the Canada Centre for Mineral and Energy Technology (CANMET) as well as some current NRCan science and technology activities, such as alternative energy programs; energy efficiency for buildings, industries and communities; clean coal; oil sands tailings and water management; community energy systems; renewable energy efficient technology projects (RET) such as RETscreen; hybrid scoop; the anti-vibration rock drill handle; mine waste management; and green mines-green energy. Other NRCan science and technology programs that were presented in the publication included materials technology laboratory relocation; corrosion management tools for the oil and gas pipeline industry; lightweight magnesium engine cradle; mine environment neutral drainage program; metallurgical processing; counter-terrorism; and clean energy. figs.

  7. Intraspecific variation in fine root respiration and morphology in response to in situ soil nitrogen fertility in a 100-year-old Chamaecyparis obtusa forest.

    Science.gov (United States)

    Makita, Naoki; Hirano, Yasuhiro; Sugimoto, Takanobu; Tanikawa, Toko; Ishii, Hiroaki

    2015-12-01

    Soil N fertility has an effect on belowground C allocation, but the physiological and morphological responses of individual fine root segments to variations in N availability under field conditions are still unclear. In this study, the direction and magnitude of the physiological and morphological function of fine roots in response to variable in situ soil N fertility in a forest site were determined. We measured the specific root respiration (Rr) rate, N concentration and morphology of fine root segments with 1-3 branching orders in a 100-year-old coniferous forest of Chamaecyparis obtusa. Higher soil N fertility induced higher Rr rates, root N concentration, and specific root length (SRL), and lower root tissue density (RTD). In all fertility levels, the Rr rates were significantly correlated positively with root N and SRL and negatively with RTD. The regression slopes of respiration with root N and RTD were significantly higher along the soil N fertility gradient. Although no differences in the slopes of Rr and SRL relationship were found across the levels, there were significant shifts in the intercept along the common slope. These results suggest that a contrasting pattern in intraspecific relationships between specific Rr and N, RTD, and SRL exists among soils with different N fertility. Consequently, substantial increases in soil N fertility would exert positive effects on organ-scale root performance by covarying the Rr, root N, and morphology for their potential nutrient and water uptake.

  8. Organochlorine pesticides (OCPs) in wetland soils under different land uses along a 100-year chronosequence of reclamation in a Chinese estuary

    Science.gov (United States)

    Bai, Junhong; Lu, Qiongqiong; Zhao, Qingqing; Wang, Junjing; Gao, Zhaoqin; Zhang, Guangliang

    2015-12-01

    Soil profiles were collected at a depth of 30 cm in ditch wetlands (DWs), riverine wetlands (RiWs) and reclaimed wetlands (ReWs) along a 100-year chronosequence of reclamation in the Pearl River Delta. In total, 16 OCPs were measured to investigate the effects of wetland reclamation and reclamation history on OCP levels. Our results showed that average ∑DDTs, HCB, MXC, and ∑OCPs were higher in surface soils of DWs compared to RiWs and ReWs. Both D30 and D20 soils contained the highest ∑OCP levels, followed by D40 and D100 soils; lower ∑OCP levels occurred in D10 soils. Higher ∑OCP levels were observed in the younger RiWs than in the older ones, and surface soils exhibited higher ∑OCP concentrations in the older ReWs compared with younger ReWs. The predominant percentages of γ-HCH in ∑HCHs (>42%) and aldrin in ∑DRINs (>46%) in most samples reflected the recent use of lindane and aldrin. The presence of dominant DDT isomers (p,p’-DDE and p,p’-DDD) indicated the historical input of DDT and significant aerobic degradation of the compound. Generally, DW soils had a higher ecotoxicological risk of OCPs than RiW and ReW soils, and the top 30 cm soils had higher ecotoxicological risks of HCHs than of DDTs.

  9. The beginnings of Orthopedic Surgery at the Mayo Clinic: A Review of the First Orthopedic Patients who Presented Over 100 Years Ago.

    Science.gov (United States)

    Camp, Christopher L; Morrey, Bernard F; Trousdale, Robert T

    2016-01-01

    Formalized training in the specialty of orthopedic surgery began at the Mayo Clinic nearly 100 years ago, and treatment of patients with musculoskeletal injuries and disease began even earlier. A robust historical patient database provides the opportunity for review of the first recorded orthopedic cases at our institution, which date back to 1907. The first 400 sequential medical charts of the Mayo Clinic's patient record database were comprehensively reviewed in order to identify the first documented orthopedic cases. Of the first 400 patients reviewed, 15 (4%) received specific orthopedic diagnoses. All presented during a three week period in 1907, and they traveled from all over the region for evaluation. The diagnoses included skeletal tuberculosis (n=6), traumatic fracture (n=3), osteomyelitis (n=2), syphilitic pathologic fracture (n=1), syphilitic ostitis of the tibia and radius (n=1), painful flat foot (n=1), and Morton's toe (n=1). Included with the records are patient demographics, diagnoses, symptoms, physical examination findings, radiograph reports, operative reports, and detailed drawings of symptomatology. Although the technology and science has advanced since the early practice of orthopedic surgery that took place over a century ago, we consider ourselves to be merely an extension of those who established the field before us. Just as the past relies on the future for the continuation of what it began so many years ago, we rely on our founders for the groundwork that they laid in creating this field of surgical medicine.

  10. Peak data for U.S. Geological Survey gaging stations, Texas network and computer program to estimate peak-streamflow frequency

    Science.gov (United States)

    Slade, R.M.; Asquith, W.H.

    1996-01-01

    About 23,000 annual peak streamflows and about 400 historical peak streamflows exist for about 950 stations in the surface-water data-collection network of Texas. These data are presented on a computer diskette along with the corresponding dates, gage heights, and information concerning the basin, and nature or cause for the flood. Also on the computer diskette is a U.S. Geological Survey computer program that estimates peak-streamflow frequency based on annual and historical peak streamflow. The program estimates peak streamflow for 2-, 5-, 10-, 25-, 50-, and 100-year recurrence intervals and is based on guidelines established by the Interagency Advisory Committee on Water Data. Explanations are presented for installing the program, and an example is presented with discussion of its options.

  11. Adolescents' explicit and implicit evaluations of hypothetical and actual peers with different bullying participant roles.

    Science.gov (United States)

    Pouwels, J Loes; Lansu, Tessa A M; Cillessen, Antonius H N

    2017-07-01

    This study examined how adolescents evaluate bullying at three levels of specificity: (a) the general concept of bullying, (b) hypothetical peers in different bullying participant roles, and (c) actual peers in different bullying participant roles. Participants were 163 predominantly ethnic majority adolescents in The Netherlands (58% girls; Mage=16.34years, SD=0.79). For the hypothetical peers, we examined adolescents' explicit evaluations as well as their implicit evaluations. Adolescents evaluated the general concept of bullying negatively. Adolescents' explicit evaluations of hypothetical and actual peers in the bullying roles depended on their own role, but adolescents' implicit evaluations of hypothetical peers did not. Adolescents' explicit evaluations of hypothetical peers and actual peers were different. Hypothetical bullies were evaluated negatively by all classmates, whereas hypothetical victims were evaluated relatively positively compared with the other roles. However, when adolescents evaluated their actual classmates, the differences between bullies and the other roles were smaller, whereas victims were evaluated the most negatively of all roles. Further research should take into account that adolescents' evaluations of hypothetical peers differ from their evaluations of actual peers. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. 47 CFR 69.608 - Carrier Common Line hypothetical net balance.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Carrier Common Line hypothetical net balance. 69.608 Section 69.608 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... net balance. The hypothetical net balance shall be equal to a Carrier Common Line revenue...

  13. Combining aptamers and in silico interaction studies to decipher the function of hypothetical proteins

    DEFF Research Database (Denmark)

    Suravajhala, Prashanth; Burri, Harsha Vardhan Reddy; Heiskanen, Arto

    2014-01-01

    We present the potential role of aptamers in elucidating the function of hypothetical proteins, as well as the possibilities provided by bioinformatics for establishing a benchmark for aptamer-protein prediction methods. With these future perspectives, the role of hypothetical proteins as target ...

  14. Methods for estimating peak discharge and flood boundaries of streams in Utah

    Science.gov (United States)

    Thomas, B.E.; Lindskov, K.L.

    1983-01-01

    Equations for estimating 2-, 5-, 10-, 25-, 50-, and 100-year peak discharges and flood depths at ungaged sites in Utah were developed using multiple-regression techniques. Ratios of 500- to 100-year values also were determined. The peak discharge equations are applicable to unregulated streams and the flood depth equations are applicable to the unregulated flow in natural stream channels. The flood depth data can be used to approximate flood prone areas. Drainage area and mean basin elevation are the two basin characteristics needed to use these equations. The standard error of estimate ranges from 38% to 74% for the 100-year peak discharge and from 23% to 33% for the 100-year flood depth. Five different flood mapping methods are described. Streams are classified into four categories as a basis for selecting a flood mapping method. Procedures for transferring flood depths obtained from the regression equations to a flood boundary map are outlined. Also, previous detailed flood mapping by government agencies and consultants is summarized to assist the user in quality control and to minimize duplication of effort. Methods are described for transferring flood frequency data from gaged to ungaged sites on the same stream. Peak discharge and flood depth frequency relations and selected basin characteristics data, updated through the 1980 water year, are tabulated for more than 300 gaging stations in Utah and adjoining states. In addition, weighted estimates of peak discharge relations based on the station data and the regression estimates are provided for each gaging station used in the regression analysis. (Author 's abstract)

  15. PEAK SHAVING CONSIDERING STREAMFLOW UNCERTAINTIES

    African Journals Online (AJOL)

    user

    The main thrust of this paper is peak shaving with a Stochastic hydro model. In peak sharing, the amount of ... Fuel cost at a conventional hydro plant is nil. On the other hand, the ... s(k) = spill at the hydro plant in period k. I(k) = loss due to ...

  16. Central control of information transmission through the intraspinal arborizations of sensory fibers examined 100 years after Ramón y Cajal.

    Science.gov (United States)

    Rudomin, Pablo

    2002-01-01

    About 100 years ago, Santiago Ramón y Cajal reported that sensory fibers entering the spinal cord have ascending and descending branches, and that each of them sends collaterals to the gray matter where they have profuse ramifications. To him this was a fundamental discovery and proposed that the intraspinal branches of the sensory fibers were "centripetal conductors by which sensory excitation is propagated to the various neurons in the gray matter". In addition, he assumed that "conduction of excitation within the intraspinal arborizations of the afferent fibers would be proportional to the diameters of the conductors", and that excitation would preferentially flow through the coarsest branches. The invariability of some elementary reflexes such as the knee jerk would be the result of a long history of plastic adaptations and natural selection of the safest neuronal organizations. There is now evidence suggesting that in the adult cat, the intraspinal branches of sensory fibers are not hard wired routes that diverge excitation to spinal neurons in an invariable manner, but rather dynamic pathways where excitation flow can be centrally addressed to reach specific neuronal targets. This central control of information flow is achieved by means of specific sets of GABAergic interneurons that produce primary afferent depolarization (PAD) via axo-axonic synapses and reduce transmitter release (presynaptic inhibition). The PAD produced by single, or by small groups of GABAergic interneurons in group I muscle afferents, can remain confined to some sets of intraspinal arborizations of the afferent fibers and not spread to nearby collaterals. In muscle spindle afferents this local character of PAD allows cutaneous and descending inputs to differentially inhibit the PAD in segmental and ascending collaterals of individual fibers, which may be an effective way to decouple the information flow arising from common sensory inputs. This feature appears to play an important role

  17. From Rail-Oriented to Automobile-Oriented Urban Development and Back. 100 Years of Paradigm Change and Transport Policy in Berlin

    Directory of Open Access Journals (Sweden)

    Friedemann Kunst

    2016-10-01

    Full Text Available Transport and its side effects are major problems in rapidly growing cities. Car traffic dominates these cities and pollutes the environment without being able to sufficiently secure the mobility of the urban population and goods. A paradigm shift in urban and transport policy will be necessary to change this situation. In spite of its different development dynamics, Berlin is an interesting example to discuss development strategies for rapidly growing cities because in the course of more than 100 years, a twofold paradigm shift has occurred in the city both conceptually and practically:  Berlin has shifted from a city dominated by rail traffic  to an automobile-oriented city,  and has then gradually transformed back into a city in which  an intertwined system of public and non-motorized individual means of transport secures the mobility of the urban population. The interdependencies on the conceptual level between urban planning and transport policies as well as on a practical level between urban structures and transport systems can be studied using the example of Berlin. Experiences with the implementation of automobile-oriented planning and the special conditions in the first decade after reunification led to protests, reflection, and a revision of the transport policy. A strategically designed process of integrated planning has brought about a trend reversal, and steered the development of transport in the direction of clearly formulated sustainability-oriented objectives. In this process, the reintegration of transport and spatial planning and a reorganization of institutional structures at the administrative level was of particular importance. Compact, rail-oriented settlement structures like in the metropolitan region of Berlin make it easier to dispense with automobiles than sprawled structures. The residual role that qualitatively improved automobiles will take in the cities of the future will have to be determined by research and

  18. Changes in stable isotopes, lignin-derived phenols, and fossil pigments in sediments of Lake Biwa, Japan: implications for anthropogenic effects over the last 100 years.

    Science.gov (United States)

    Hyodo, Fujio; Tsugeki, Narumi; Azuma, Jun-Ichi; Urabe, Jotaro; Nakanishi, Masami; Wada, Eitaro

    2008-09-15

    We measured stable nitrogen (N) and carbon (C) isotope ratios, lignin-derived phenols, and fossil pigments in sediments of known ages to elucidate the historical changes in the ecosystem status of Lake Biwa, Japan, over the last 100 years. Stable N isotope ratios and algal pigments in the sediments increased rapidly from the early 1960s to the 1980s, and then remained relatively constant, indicating that eutrophication occurred in the early 1960s but ceased in the 1980s. Stable C isotope ratios of the sediment increased from the 1960s, but decreased after the 1980s to the present. This decrease in stable C isotope ratios after the 1980s could not be explained by annual changes in either terrestrial input or algal production. However, when the C isotope ratios were corrected for the Suess effect, the shift to more negative isotopic value in atmospheric CO(2) by fossil fuel burning, the isotopic value showed a trend, which is consistent with the other biomarkers and the monitoring data. The trend was also mirrored by the relative abundance of lignin-derived phenols, a unique organic tracer of material that originated from terrestrial plants, which decreased in the early 1960s and recovered to some degree in the 1980s. We detected no notable difference in the composition of lignin phenols, suggesting that the terrestrial plant composition did not change markedly. However, we found that lignin accumulation rate increased around the 1980s. These results suggest that although eutrophication has stabilized since the 1980s, allochthonous organic matter input has changed in Lake Biwa over the past 25 years.

  19. Fractionation, transfer, and ecological risks of heavy metals in riparian and ditch wetlands across a 100-year chronosequence of reclamation in an estuary of China

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Rong [State Key Laboratory of Water Environment Stimulation, School of Environment, Beijing Normal University, Beijing 100875 (China); School of Nature Conservation, Beijing Forestry University, Beijing 100083 (China); Bai, Junhong, E-mail: junhongbai@163.com [State Key Laboratory of Water Environment Stimulation, School of Environment, Beijing Normal University, Beijing 100875 (China); Lu, Qiongqiong; Zhao, Qingqing; Gao, Zhaoqin; Wen, Xiaojun; Liu, Xinhui [State Key Laboratory of Water Environment Stimulation, School of Environment, Beijing Normal University, Beijing 100875 (China)

    2015-06-01

    The effect of reclamation on heavy metal concentrations and the ecological risks in ditch wetlands (DWs) and riparian wetlands (RWs) across a 100-year chronosequence in the Pearl River Estuary of China was investigated. Concentrations of 4 heavy metals (Cd, Cu, Pb, and Zn) in soil and plant samples, and sequential extracts of soil samples were determined, using inductively coupled plasma atomic absorption spectrometry. Results showed that heavy metal concentrations were higher in older DW soils than in the younger ones, and that the younger RW soils contained higher heavy metal concentrations compared to the older ones. Although the increasing tendency of heavy metal concentrations in soil was obvious after wetland reclamation, the metals Cu, Pb, and Zn exhibited low or no risks to the environment based on the risk assessment code (RAC). Cd, on the other hand, posed a medium or high risk. Cd, Pb, and Zn were mainly bound to Fe–Mn oxide, whereas most of Cu remained in the residual phase in both ditch and riparian wetland soils, and the residual proportions generally increased with depth. Bioconcentration and translocation factors for most of these four heavy metals significantly decreased in the DWs with older age (p < 0.05), whereas they increased in the RWs with younger age (p < 0.05). The DW soils contained higher concentrations of heavy metals in the organic fractions, whereas there were more carbonate and residual fractions in the RW soils. The non-bioavailable fractions of Cu and Zn, and the organic-bound Cd and Pb significantly inhibited plant growth. - Highlights: • Heavy metals in ditch wetland accumulated with increasing reclamation history. • Heavy metals exist in the Fe–Mn oxides and residual fractions in both wetlands. • Cd posed a medium to high environmental risk while low risk for other metals. • Long reclamation history caused lower BCFs and TFs in DWs and higher levels in RWs. • RW soils contained more heavy metals in the carbonate

  20. Upwelling and anthropogenic forcing on phytoplankton productivity and community structure changes in the Zhejiang coastal area over the last 100 years

    Institute of Scientific and Technical Information of China (English)

    DUAN Shanshan; XING Lei; ZHANG Hailong; FENG Xuwen; YANG Haili; ZHAO Meixun

    2014-01-01

    Phytoplankton productivity and community structure in marginal seas have been altered significantly dur-ing the past three decades, but it is still a challenge to distinguish the forcing mechanisms between climate change and anthropogenic activities. High time-resolution biomarker records of two 210Pb-dated sediment cores (#34:28.5°N, 122.272°E;CJ12-1269:28.861 9°N, 122.515 3°E) from the Min-Zhe coastal mud area were compared to reveal changes of phytoplankton productivity and community structure over the past 100 years. Phytoplankton productivity started to increase gradually from the 1970s and increased rapidly after the late 1990s at Site #34;and it started to increase gradually from the middle 1960s and increased rapidly after the late 1980s at Site CJ12-1269. Productivity of Core CJ12-1269 was higher than that of Core #34. Phy-toplankton community structure variations displayed opposite patterns in the two cores. The decreasing D/B (dinosterol/brassicasterol) ratio of Core #34 since the 1960s revealed increased diatom contribution to total productivity. In contrast, the increasing D/B ratio of Core CJ12-1269 since the 1950s indicated in-creased dinoflagellate contribution to total productivity. Both the productivity increase and the increased dinoflagellate contribution in Core CJ12-1269 since the 1950-1960s were mainly caused by anthropogenic activities, as the location was closer to the Changjiang River Estuary with higher nutrient concentration and decreasing Si/N ratios. However, increased diatom contribution in Core #34 is proposed to be caused by increased coastal upwelling, with higher nutrient concentration and higher Si/N ratios.

  1. How to use your peak flow meter

    Science.gov (United States)

    Peak flow meter - how to use; Asthma - peak flow meter; Reactive airway disease - peak flow meter; Bronchial asthma - peak flow meter ... If your airways are narrowed and blocked due to asthma, your peak flow values drop. You can ...

  2. Doppler peaks from active perturbations

    CERN Document Server

    Magueijo, J; Coulson, D; Ferreira, P; Magueijo, Joao; Albrecht, Andreas; Coulson, David; Ferreira, Pedro

    1995-01-01

    We examine how the qualitative structure of the Doppler peaks in the angular power spectrum of the cosmic microwave anisotropy depends on the fundamental nature of the perturbations which produced them. The formalism of Hu and Sugiyama is extended to treat models with cosmic defects. We discuss how perturbations can be ``active'' or ``passive'' and ``incoherent'' or ``coherent'', and show how causality and scale invariance play rather different roles in these various cases. We find that the existence of secondary Doppler peaks and the rough placing of the primary peak unambiguously reflect these basic properties.

  3. Analysis of the Magnitude and Frequency of Peak Discharge and Maximum Observed Peak Discharge in New Mexico and Surrounding Areas

    Science.gov (United States)

    Waltemeyer, Scott D.

    2008-01-01

    (mean value is 62, and median value is 59) for the 100-year flood. The 1996 investigation standard error of prediction for the flood regions ranged from 41 to 96 percent (mean value is 67, and median value is 68) for the 100-year flood that was analyzed by using generalized least-squares regression analysis. Overall, the equations based on generalized least-squares regression techniques are more reliable than those in the 1996 report because of the increased length of record and improved geographic information system (GIS) method to determine basin and climatic characteristics. Flood-frequency estimates can be made for ungaged sites upstream or downstream from gaging stations by using a method that transfers flood-frequency data at the gaging station to the ungaged site by using a drainage-area ratio adjustment equation. The peak discharge for a given recurrence interval at the gaging station, drainage-area ratio, and the drainage-area exponent from the regional regression equation of the respective region is used to transfer the peak discharge for the recurrence interval to the ungaged site. Maximum observed peak discharge as related to drainage area was determined for New Mexico. Extreme events are commonly used in the design and appraisal of bridge crossings and other structures. Bridge-scour evaluations are commonly made by using the 500-year peak discharge for these appraisals. Peak-discharge data collected at 293 gaging stations and 367 miscellaneous sites were used to develop a maximum peak-discharge relation as an alternative method of estimating peak discharge of an extreme event such as a maximum probable flood.

  4. Indications of progressive desiccation of the Transvaal Lowveld over the past 100 years, and implications for the water stabilization programme in the Kruger National Park

    Directory of Open Access Journals (Sweden)

    U. De V. Pienaar

    1985-12-01

    Full Text Available All available rainfall statistics recorded for the Kruger National Park area since 1907, coupled with an analysis of all the historical climatological data on hand, appear to confirm the quasi-twenty-year rainfall oscillation in precipitation pattern for the summer rainfall area. This was first pointed out by Tyson & Dyer (1975. The dendrochronological data obtained by Hall (1976 from a study of growth rings of a very old yellowwood tree (Podocarpus falcatus in Natal, also appear to indicate a superimposed, long-term (80-100 years pattern of alternate below- average and above-average rainfall periods. The historical data relating to climate in the park, during the past century or two, seem to bear out such a pattern. If this can be confirmed, it will be an enormous aid not only in wildlife-management planning, but also to agriculturists, demographic planners and others. It would appear that the long, relatively dry rainfall period of 1860-1970, with its concomitant progressive desiccation of the @ area in question, has passed over into the next aboveverage rainfall era. This does not mean that there will be no further cataclysmic droughts during future rainfall trough periods. It is therefore wise to plan ahead to meet such contingencies. The present water distribution pattern in the park (natural plus artificial water is conspicuously still well below that which pertained, during dry seasons, at the turn of the century, when the Sabi and Shingwedzi game reserves were proclaimed. It is the declared policy of the National Parks Board of Trustees to simulate natural regulating mechanisms as closely as possible. In consequence the artificial water-for-game program is a long way from completion. The large numbers of game animals in the park (including dominant species such as elephant Loxodonta africana and buffalo Syncerus coffer can no longer migrate out of the area to escape natural catastrophes (such as the crippling droughts of 1911-1917, the

  5. Make peak flow a habit!

    Science.gov (United States)

    ... asthma - peak flow References Durrani SR, Busse WW. Management of asthma in adolescents and adults. In: Adkinson NF Jr, Bochner BS, Burks AW, et al, eds. Middleton's Allergy Principles and Practice . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap ...

  6. [Science in the crosshairs of enlightenment. Significance of hypothetical thinking].

    Science.gov (United States)

    Wieland, Wolfgang

    2011-01-01

    To further the enlightenment primarily or even only by means of science was the hope of most representatives of the movement of the enlightenment which gave its name to a whole period of European cultural history. Only a few of its representatives, like Montesquieu and Rousseau, doubted for good reasons, whether and how the goals of the enlightenment can be reached at all by the means of science alone. In his Discours préliminaires to the Encyclopédie D'Alembert still wanted to limit science proper to the narrower field of those kinds of research which were strictly based on observations and calculations alone. In this way he remained committed to Descartes' ideal method of receiving authentic knowledge only by deduction from evident axioms or fundamental theorems. Pascal's casual discovery of the calculation of probabilities allowed to apply mathematics on the hidden laws of the apparent casualties of the human life world. Bacon's project of empirical science as a rational and methodological art of conducting experiments could replace the methodological ideal of science more geometrico. Lichtenberg's refined sensibility for the subjunctive linguistic forms of hypothetical thinking indicates a new understanding of inventing and testing hypotheses as the two most important methods of the experimental sciences when compared to the formal sciences of logic and mathematics. Whoever is studying the history of science of modern times in the cross wire of the enlightenment, will realize soon that science has always been in need of being illuminated about its own chances, risks and side effects. The project of enlightenment through science had to be complemented by the project of an enlightenment about science right from its beginning. Because of the implicit risks and side effects the project of enlightenment has to be enlightenment despite of science and because of science. On the one hand, as a special form of human practice the sciences are directed towards

  7. Peak Oil and other threatening peaks-Chimeras without substance

    Energy Technology Data Exchange (ETDEWEB)

    Radetzki, Marian, E-mail: marian@radetzki.bi [Lulea University of Technology (Sweden)

    2010-11-15

    The Peak Oil movement has widely spread its message about an impending peak in global oil production, caused by an inadequate resource base. On closer scrutiny, the underlying analysis is inconsistent, void of a theoretical foundation and without support in empirical observations. Global oil resources are huge and expanding, and pose no threat to continuing output growth within an extended time horizon. In contrast, temporary or prolonged supply crunches are indeed plausible, even likely, on account of growing resource nationalism denying access to efficient exploitation of the existing resource wealth.

  8. Peak Oil and other threatening peaks. Chimeras without substance

    Energy Technology Data Exchange (ETDEWEB)

    Radetzki, Marian [Luleaa University of Technology (Sweden)

    2010-11-15

    The Peak Oil movement has widely spread its message about an impending peak in global oil production, caused by an inadequate resource base. On closer scrutiny, the underlying analysis is inconsistent, void of a theoretical foundation and without support in empirical observations. Global oil resources are huge and expanding, and pose no threat to continuing output growth within an extended time horizon. In contrast, temporary or prolonged supply crunches are indeed plausible, even likely, on account of growing resource nationalism denying access to efficient exploitation of the existing resource wealth. (author)

  9. Ultrasonic Transducer Peak-to-Peak Optical Measurement

    Directory of Open Access Journals (Sweden)

    Pavel Skarvada

    2012-01-01

    Full Text Available Possible optical setups for measurement of the peak-to-peak value of an ultrasonic transducer are described in this work. The Michelson interferometer with the calibrated nanopositioner in reference path and laser Doppler vibrometer were used for the basic measurement of vibration displacement. Langevin type of ultrasonic transducer is used for the purposes of Electro-Ultrasonic Nonlinear Spectroscopy (EUNS. Parameters of produced mechanical vibration have to been well known for EUNS. Moreover, a monitoring of mechanical vibration frequency shift with a mass load and sample-transducer coupling is important for EUNS measurement.

  10. MODFLOW-NWT model of a hypothetical stream-aquifer system to assess capture map bias

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — A MODFLOW-NWT (version 1.0.9) model of a hypothetical stream-aquifer system is presented for the evaluation and characterization of capture map bias. The...

  11. Explaining the discrepancy between intentions and actions: the case of hypothetical bias in contingent valuation.

    Science.gov (United States)

    Ajzen, Icek; Brown, Thomas C; Carvajal, Franklin

    2004-09-01

    An experiment was designed to account for intention-behavior discrepancies by applying the theory of planned behavior to contingent valuation. College students (N = 160) voted in hypothetical and real payment referenda to contribute $8 to a scholarship fund. Overestimates of willingness to pay in the hypothetical referendum could not be attributed to moderately favorable latent dispositions. Instead, this hypothetical bias was explained by activation of more favorable beliefs and attitudes in the context of a hypothetical rather than a real referendum. A corrective entreaty was found to eliminate this bias by bringing beliefs, attitudes, and intentions in line with those in the real payment situation. As a result, the theory of planned behavior produced more accurate prediction of real payment when participants were exposed to the corrective entreaty.

  12. Uncertainty Analysis of Climate Warming During the Last 100 Years%近百年气候变暖的不确定性分析

    Institute of Scientific and Technical Information of China (English)

    赵宗慈; 王绍武; 罗勇; 江滢

    2009-01-01

    As mentioned in the IPCC report, the linear trend of the global annual mean surface air temperature during the last 100 years (1906 to 2005) is 0.74℃(in the range of 0.56 to 0.921℃). The wanning trend in China is 0.53~0.86℃ during the same period. But it should emphasized that there are some uncertainties and gaps in the information about the recent climate warming, especially in some special regions such as in China. The uncertainties of climate warming in China come from both lack of the observed data during the first half of the 20th century and the urbanization process (heat island effects) during the second half of the 20th century that might contribute 25% of the total wanning. The climate warming in China during the last 50 years is not only contributed by the human activity, but also by the urbanization, the natural periodicity and decadal variability, dimming and brightening of the solar radiation, as well as other forcing factors such as solar activity, volcanic activity and interactions inside the climate system. The fractional uncertainties of the future climate prediction and projections vary due to internal variability of the global climate system, climatemodel uncertainty and scenario uncertainty. The global climate models do not have adequately fine resolutions due to the lack of high speed computers, with inveracious simulations by the models, especially in the regional scales. The parameterizations of the physical, chemical and biological processes in the global climate system are complicated. The present climate models can hardly describe those processes, interactions and the feedback mechanisms, . such as clouds-aerosols-radiation feedbacks. The future climate changes will be caused by both natural and anthropogenic forcing factors. It is difficult to predict solar and volcanic activities in a long period. The human activities in future are provided as some scenarios, not the real human emissions. Therefore, the reliability of climate

  13. Detection and Mitigation of Hypothetical Bias in Contingent Valuation With An Application To Curbside Recycling

    OpenAIRE

    Aadland, David; Caplan, Arthur J.

    2001-01-01

    In this paper, we use a unique curbside-recycling data set to test the effectiveness of "cheap talk" and "preference uncertainty" in mitigating hypothetical bias in contingent valuation. The sample includes two types of households-those located in communities with curbside recycling programs (mandatory or voluntary) and those in communities without curbside recycling. Using stated and revealed preference data, detect significant hypothetical bias. Cheap talk and preference-uncertainty control...

  14. Mitigating Hypothetical Bias in Stated Preference Data: Evidence from Sports Tourism

    OpenAIRE

    John Whitehead; Melissa S. Weddell; Pete Groothuis

    2014-01-01

    One of the major criticisms of stated preference data is hypothetical bias. Using a unique data set of both stated and actual behavior we test for hypothetical bias of stated preference survey responses. We consider whether respondents tend to overstate their participatory sporting event behavior ex ante when compared to their actual behavior at different registration fees. We find that behavioral intentions accurately predicts actual behavior at a middle level of respondent certainty, over p...

  15. Proceedings of the Conference on Hypothetical Reasoning, 23-24 August 2014, Tübingen

    OpenAIRE

    Piecha, Thomas; Schroeder-Heister, Peter

    2015-01-01

    Hypothetical reasoning or reasoning under assumptions is a key concept of logic, philosophy of science and mathematics. The Conference on Hypothetical Reasoning focussed on its logical aspects, such as assumption-based calculi and their proof theory, logical consequence from a proof-theoretic or model-theoretic point of view, logics of conditionals, proof systems, structure of assumption-based proofs, hypotheses in proof-theoretic semantics, notions of implication, substructural logics, hy...

  16. Steeper delay and probability discounting of potentially real versus hypothetical cigarettes (but not money) among smokers.

    Science.gov (United States)

    Green, Ryan M; Lawyer, Steven R

    2014-10-01

    There is a strong relationship between drug use and the tendency to discount the value of outcomes as a function of their delay and probability. Most discounting researchers use hypothetical monetary outcomes to establish discounting patterns among human subjects, who tend to discount the value of hypothetical money and real money similarily. However, no research to date has examined whether hypothetical non-monetary outcomes are discounted similarly to real non-monetary outcomes. In this study, smokers were assigned randomly to complete delay and probability discounting tasks for money and cigarettes that were either potentially real (n=33) or hypothetical (n=31). Consistent with previous research, smokers discounted the value of hypothetical and potentially real money similarly. However, smokers evidenced steeper rates of discounting for potentially real cigarettes in both delay and probability discounting. These findings suggest domain-specific discounting patterns in which potentially real and hypothetical outcomes may be synonymous in the context of monetary outcomes, but not in the context of non-monetary outcomes. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Significance Tests for Periodogram Peaks

    CERN Document Server

    Frescura, F A M; Frank, B S

    2007-01-01

    We discuss methods currently in use for determining the significance of peaks in the periodograms of time series. We discuss some general methods for constructing significance tests, false alarm probability functions, and the role played in these by independent random variables and by empirical and theoretical cumulative distribution functions. We also discuss the concept of "independent frequencies" in periodogram analysis. We propose a practical method for estimating the significance of periodogram peaks, applicable to all time series irrespective of the spacing of the data. This method, based on Monte Carlo simulations, produces significance tests that are tailor-made for any given astronomical time series.

  18. Hubbert's Peak -- A Physicist's View

    Science.gov (United States)

    McDonald, Richard

    2011-04-01

    Oil, as used in agriculture and transportation, is the lifeblood of modern society. It is finite in quantity and will someday be exhausted. In 1956, Hubbert proposed a theory of resource production and applied it successfully to predict peak U.S. oil production in 1970. Bartlett extended this work in publications and lectures on the finite nature of oil and its production peak and depletion. Both Hubbert and Bartlett place peak world oil production at a similar time, essentially now. Central to these analyses are estimates of total ``oil in place'' obtained from engineering studies of oil reservoirs as this quantity determines the area under the Hubbert's Peak. Knowing the production history and the total oil in place allows us to make estimates of reserves, and therefore future oil availability. We will then examine reserves data for various countries, in particular OPEC countries, and see if these data tell us anything about the future availability of oil. Finally, we will comment on synthetic oil and the possibility of carbon-neutral synthetic oil for a sustainable future.

  19. Flood hazards along the Toutle and Cowlitz rivers, Washington, from a hypothetical failure of Castle Lake blockage

    Science.gov (United States)

    Laenen, Antonius; Orzol, L.L.

    1987-01-01

    A recent evaluation of groundwater and material in the blockage impounding Castle Lake shows that the blockage is potentially unstable against failure from piping due to heave and internal erosion when groundwater levels are seasonally high. There is also a remote possibility that a 6.8 or greater magnitude earthquake could occur in the Castle Lake area when groundwater levels are critically high. If this situation occurs, the debris blockage that confines Castle Lake could breach from successive slope failure with liquefaction of a portion of the blockage. A dam-break computer model was used to simulate discharge through a hypothetical breach in the Castle Lake blockage that could be caused by failure by heave, internal erosion, or liquefaction. Approximately 18,500 acre-ft of stored water would be released from an assumed breach that fully developed to a 1,000-ft width over a 15-minute time period. The resulting flood, incorporating 3.4 x 10 to the 6th power cu yd of the debris blockage, would reach a peak magnitude of 1,500,000 cu ft/s (cubic feet per second). The flood is also assumed to incorporate an additional 137x10 to the 6th power cu yd of saturated debris material from downstream deposits. Flow is considered to be hyperconcentrated with sediment throughout the course of the flood. The hypothetical hyperconcentrated flow is routed downstream, superimposed on normal winter flood flows by use of a one-dimensional unsteady-state numerical streamflow simulation model. From a starting magnitude of 1,500,000 cu ft/s, the peak increases to 2,100,000 cu ft/s at N-1 Dam (12 mi downstream) and attenuates to 1,200,000 cu ft/s at Kid Valley (25 mi downstream) , to 100,000 cu ft/s at Longview and the confluence of the Columbia River (65 mi downstream). From time of breach, the flood peak would take 2.2 hr to reach Toutle, 3.8 hr to reach Castle Rock, and 8.5 hr to reach Longview. Communities of Toutle , Castle Rock, Kelso, and Longview would experience extreme to

  20. Discriminate Modelling of Peak and Off-Peak Motorway Capacity

    Directory of Open Access Journals (Sweden)

    Hashim Mohammed Alhassan

    2013-02-01

    Full Text Available Traffic theory is concerned with the movement of discrete objects in real time over a finite network in 2 Dimensions. It is compatible with or dependent on fundamental diagram of traffic. Without question traffic flow is an essential quantitative parameter that is used in planning, designs and roadway improvements.  Road capacity is significant because it is an important indicator of road performance and can point road managers in the right road maintenance and traffic management direction. In this paper four direct empirical capacity measurement methods have been considered. To test the efficacy of each method, data for peak period, off-peak and transition to peak have been used. The headway and the volume methods lack predictive capability and are suitable only for current assessment of flow rates.  The product limit method is weak in its predictive capability in view of the arbitrariness in the selection of the capacity value. It is also an extreme value method; hence not all volume data can be used with this method. The fundamental diagram method has good predictive capability and furnishes capacity values consistent with the standard of the facility. Unlike other methods, it does not rely on bottleneck conditions to deliver the capacity value.  The paper concluded that each method is uniquely suited to prevailing conditions and can be so employed.

  1. Longitudinal peak detected Schottky spectrum

    CERN Document Server

    Shaposhnikova, E

    2009-01-01

    The "peak detected Schottky" spectrum is a diagnostic used since the late seventies for beam observation in the SPS and now already applied to the LHC. This tool was always believed, however without proof, to give a good picture of the particle distribution in synchrotron frequencies similar to the longitudinal Schottky spectrum of unbunched beam for revolution frequencies.In this paper an analysis of this measurement technique is presented both in a general form and for the particular realisation in the SPS. In addition the limitations of the present experimental set-up are discussed together with possible improvements. The analysis shows that for an optimised experimental set-up the spectrum of the peak detected signal is very close to the synchrotron frequency distribution inside the bunch - much closer than that given by the traditional longitudinal bunched-beam Schottky spectrum.

  2. Expression profiling of hypothetical genes in Desulfovibrio vulgaris leads to improved functional annotation

    Energy Technology Data Exchange (ETDEWEB)

    Elias, Dwayne A.; Mukhopadhyay, Aindrila; Joachimiak, Marcin P.; Drury, Elliott C.; Redding, Alyssa M.; Yen, Huei-Che B.; Fields, Matthew W.; Hazen, Terry C.; Arkin, Adam P.; Keasling, Jay D.; Wall, Judy D.

    2008-10-27

    Hypothetical and conserved hypothetical genes account for>30percent of sequenced bacterial genomes. For the sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough, 347 of the 3634 genes were annotated as conserved hypothetical (9.5percent) along with 887 hypothetical genes (24.4percent). Given the large fraction of the genome, it is plausible that some of these genes serve critical cellular roles. The study goals were to determine which genes were expressed and provide a more functionally based annotation. To accomplish this, expression profiles of 1234 hypothetical and conserved genes were used from transcriptomic datasets of 11 environmental stresses, complemented with shotgun LC-MS/MS and AMT tag proteomic data. Genes were divided into putatively polycistronic operons and those predicted to be monocistronic, then classified by basal expression levels and grouped according to changes in expression for one or multiple stresses. 1212 of these genes were transcribed with 786 producing detectable proteins. There was no evidence for expression of 17 predicted genes. Except for the latter, monocistronic gene annotation was expanded using the above criteria along with matching Clusters of Orthologous Groups. Polycistronic genes were annotated in the same manner with inferences from their proximity to more confidently annotated genes. Two targeted deletion mutants were used as test cases to determine the relevance of the inferred functional annotations.

  3. Structure and functional annotation of hypothetical proteins having putative Rubisco activase function from Vitis vinifera.

    Science.gov (United States)

    Kumar, Suresh

    2015-01-01

    Rubisco is a very large, complex and one of the most abundant proteins in the world and comprises up to 50% of all soluble protein in plants. The activity of Rubisco, the enzyme that catalyzes CO2 assimilation in photosynthesis, is regulated by Rubisco activase (Rca). In the present study, we searched for hypothetical protein of Vitis vinifera which has putative Rubisco activase function. The Arabidopsis and tobacco Rubisco activase protein sequences were used as seed sequences to search against Vitis vinifera in UniprotKB database. The selected hypothetical proteins of Vitis vinifera were subjected to sequence, structural and functional annotation. Subcellular localization predictions suggested it to be cytoplasmic protein. Homology modelling was used to define the three-dimensional (3D) structure of selected hypothetical proteins of Vitis vinifera. Template search revealed that all the hypothetical proteins share more than 80% sequence identity with structure of green-type Rubisco activase from tobacco, indicating proteins are evolutionary conserved. The homology modelling was generated using SWISS-MODEL. Several quality assessment and validation parameters computed indicated that homology models are reliable. Further, functional annotation through PFAM, CATH, SUPERFAMILY, CDART suggested that selected hypothetical proteins of Vitis vinifera contain ATPase family associated with various cellular activities (AAA) and belong to the AAA+ super family of ring-shaped P-loop containing nucleoside triphosphate hydrolases. This study will lead to research in the optimization of the functionality of Rubisco which has large implication in the improvement of plant productivity and resource use efficiency.

  4. Drivers of peak sales for pharmaceutical brands

    NARCIS (Netherlands)

    Fischer, Marc; Leeflang, Peter S. H.; Verhoef, Peter C.

    2010-01-01

    Peak sales are an important metric in the pharmaceutical industry. Specifically, managers are focused on the height-of-peak-sales and the time required achieving peak sales. We analyze how order of entry and quality affect the level of peak sales and the time-to-peak-sales of pharmaceutical brands.

  5. Modeled future peak streamflows in four coastal Maine rivers

    Science.gov (United States)

    Hodgkins, Glenn A.; Dudley, Robert W.

    2013-01-01

    the magnitude of air temperatures increase in the four basins, peak flows decrease by larger amounts. If precipitation is held constant (no change from historical values), 17 to 26 percent decreases in peak flow occur at the four basins when temperature is increased by 7.2°F. If temperature is held constant, 26 to 38 percent increases in peak flow result from a 15-percent increase in precipitation. The largest decreases in peak flows at the four basins result from 15-percent decreases in precipitation combined with temperature increases of 10.8°F. The largest increases in peak flows generally result from 30-percent increases in precipitation combined with 3.6 °F decreases in temperatures. In many cases when temperature and precipitation both increase, small increases or decreases in annual daily maximum peak flows result. For likely changes projected for the northeastern United States for the middle of the 21st century (temperature increase of 3.6 °F and precipitation increases of 0 to 15 percent), peak-flow changes at the four coastal Maine basins in this study are modeled to be evenly distributed between increases and decreases of less than 25 percent. Peak flows with 50-percent and 1-percent AEPs (equivalent to 2-year and 100-year recurrence interval peak flows, respectively) were calculated for the four basins in the study using the PRMS-modeled annual daily maximum peak flows. Modeled peak flows with 50-percent and 1-percent AEPs with adjusted temperatures and precipitation were compared to unadjusted (historical) modeled values. Changes in peak flows with 50-percent AEPs are similar to changes in annual daily maximum peak flow; changes in peak flows with 1-percent AEPs are similar in pattern to changes in annual daily maximum peak flow, but some of the changes associated with increasing precipitation are much larger than changes in annual daily maximum peak flow. Substantial decreases in maximum annual winter snowpack water equivalent are modeled to occur

  6. Structural Analysis of Hypothetical Proteins from Helicobacter pylori: An Approach to Estimate Functions of Unknown or Hypothetical Proteins

    Directory of Open Access Journals (Sweden)

    Bong-Jin Lee

    2012-06-01

    Full Text Available Helicobacter pylori (H. pylori have a unique ability to survive in extreme acidic environments and to colonize the gastric mucosa. It can cause diverse gastric diseases such as peptic ulcers, chronic gastritis, mucosa-associated lymphoid tissue (MALT lymphoma, gastric cancer, etc. Based on genomic research of H. pylori, over 1600 genes have been functionally identified so far. However, H. pylori possess some genes that are uncharacterized since: (i the gene sequences are quite new; (ii the function of genes have not been characterized in any other bacterial systems; and (iii sometimes, the protein that is classified into a known protein based on the sequence homology shows some functional ambiguity, which raises questions about the function of the protein produced in H. pylori. Thus, there are still a lot of genes to be biologically or biochemically characterized to understand the whole picture of gene functions in the bacteria. In this regard, knowledge on the 3D structure of a protein, especially unknown or hypothetical protein, is frequently useful to elucidate the structure-function relationship of the uncharacterized gene product. That is, a structural comparison with known proteins provides valuable information to help predict the cellular functions of hypothetical proteins. Here, we show the 3D structures of some hypothetical proteins determined by NMR spectroscopy and X-ray crystallography as a part of the structural genomics of H. pylori. In addition, we show some successful approaches of elucidating the function of unknown proteins based on their structural information.

  7. The effect of the solemn oath script in hypothetical choice experiment survey: A pilot study

    NARCIS (Netherlands)

    Magistris, de T.; Pascucci, S.

    2014-01-01

    We test the effect of the solemn oath (HO) in Hypothetical CE Survey (CE). We conducted CE surveys with three treatments: (1) CE without a cognitive task, (2) CE with a CT script, and (3) CE with a HO. Results generally suggest lower WTPs values with the HO, than without the HO script.

  8. An Assessment of the Hypothetical Impact of Drug Abuse on Combat Capability. Volume I.

    Science.gov (United States)

    1979-12-01

    25 I .4 Jill 1.6 MICROCOPY RESOLUTION TEST CHART NATIONAt BIURIA OF gMANI£ IWOI) A LEVEL AD SAI-80-113-WA AN ASSESSMENT OF THE HYPOTHETICAL IMPACTo OF...potential loss of unit effectiveness in each of these units. The resulting measure of unit effectiveness provides a powerful analy- tic tool for comparing

  9. Developing a Hypothetical Multi-Dimensional Learning Progression for the Nature of Matter

    Science.gov (United States)

    Stevens, Shawn Y.; Delgado, Cesar; Krajcik, Joseph S.

    2010-01-01

    We describe efforts toward the development of a hypothetical learning progression (HLP) for the growth of grade 7-14 students' models of the structure, behavior and properties of matter, as it relates to nanoscale science and engineering (NSE). This multi-dimensional HLP, based on empirical research and standards documents, describes how students…

  10. Can a Repeated Opt-Out Reminder remove hypothetical bias in discrete choice experiments?

    DEFF Research Database (Denmark)

    Alemu, Mohammed Hussen; Olsen, Søren Bøye

    Recent papers have suggested that use of a so-called Repeated Opt-Out Reminder (ROOR) might mitigate hypothetical bias in stated Discrete Choice Experiments (DCE), but evidence so far has only been circumstantial. We provide the first comprehensive test of whether a ROOR can actually mitigate...

  11. What We Say and What We Do: The Relationship between Real and Hypothetical Moral Choices

    Science.gov (United States)

    FeldmanHall, Oriel; Mobbs, Dean; Evans, Davy; Hiscox, Lucy; Navrady, Lauren; Dalgleish, Tim

    2012-01-01

    Moral ideals are strongly ingrained within society and individuals alike, but actual moral choices are profoundly influenced by tangible rewards and consequences. Across two studies we show that real moral decisions can dramatically contradict moral choices made in hypothetical scenarios (Study 1). However, by systematically enhancing the…

  12. The impact of arbitrarily applicable relational responding on evaluative learning about hypothetical money and shock outcomes.

    Science.gov (United States)

    Dymond, Simon; Molet, Mikael; Davies, Lynette

    2017-08-01

    Evaluative learning comprises changes in preferences after co-occurrences between conditioned stimuli (CSs) and an unconditioned stimulus (US) of affective value. Co-occurrences may involve relational responding. Two experiments examined the impact of arbitrary relational responding on evaluative preferences for hypothetical money and shock outcomes. In Experiment 1, participants were trained to make arbitrary relational responses by placing CSs of the same size but different colours into boxes and were then instructed that these CSs represented different intensities of hypothetical USs (money or shock). Liking ratings of the CSs were altered in accordance with the underlying bigger/smaller than relations. A reversal of preference was also observed: the CS associated with the smallest hypothetical shock was rated more positively than the CS associated with the smallest amount of hypothetical money. In Experiment 2, procedures from Relational Frame Theory (RFT) established a relational network of more than/less than relations consisting of five CSs (A-B-C-D-E). Overall, evaluative preferences were altered, but not reversed, depending on (a) how stimuli had been related to one another during the learning phase and (b) whether those stimuli referred to money or shocks. The contribution of RFT to evaluative learning research is discussed.

  13. Understanding Solitude: Young Children's Attitudes and Responses toward Hypothetical Socially Withdrawn Peers

    Science.gov (United States)

    Coplan, Robert J.; Girardi, Alberta; Findlay, Leanne C.; Frohlick, Sherri L.

    2007-01-01

    The goal of the present study was to explore young children's attitudes and responses to different forms of social withdrawal by eliciting responses to hypothetical vignettes. Participants included 137 children (49 boys, 88 girls) in kindergarten and grade 1 classes (M[subscript age] = 75.94 months, SD = 9.03) in Ottawa, Canada. Parents rated…

  14. fMRI evidence of a hot-cold empathy gapin hypothetical and real aversive choices

    Directory of Open Access Journals (Sweden)

    Min Jeong Kang

    2013-06-01

    Full Text Available Hypothetical bias is the common finding that hypothetical monetary values for goods are higher than real values. We extend this research to the domain of bads such as consumer and household choices made to avoid aversive outcomes (e.g., insurance. Previous evidence of hot-cold empathy gaps suggest food disgust is likely to be strongly underestimated in hypothetical (cold choice. Depending on relative underestimation of food disgust and pain of spending, the hypothetical bias for aversive bads can go in the typical direction for goods, disappear, or reverse in sign. We find that the bias is reversed in sign—subjects pay more to avoid bads when choice is real. fMRI shows that real choice more strongly activates striatum and medial prefrontal cortex (reward regions and shows distinct activity in insula and amygdala (disgust and fear regions. The neural findings suggest ways to exogeneously manipulate or record brain activity in order to create better forecasts of actual consumer choice.

  15. Consequences in Norway after a hypothetical accident at Sellafield - Predicted impacts on the environment.

    Energy Technology Data Exchange (ETDEWEB)

    Thoerring, H.; Liland, A.

    2010-12-15

    This report deals with the environmental consequences in Norway after a hypothetical accident at Sellafield. The investigation is limited to the terrestrial environment, and focus on animals grazing natural pastures, plus wild berries and fungi. Only 137Cs is considered. The predicted consequences are severe, in particular for mutton and goat milk production. (Author)

  16. Physicians' willingness to grant requests for assistance in dying for children: a study of hypothetical cases

    NARCIS (Netherlands)

    Vrakking, A.M.; Heide, van der A.; Looman, C.W.; Delden, van J.J.M.; Philipsen, B.D.; Maas, van der P.J.; Wal, van der G.

    2005-01-01

    OBJECTIVE: To study the willingness of Dutch physicians to use potentially life-shortening or lethal drugs for severely ill children. STUDY DESIGN: We asked 63 pediatricians about their approach to 10 hypothetical cases of children with cancer. The age of the child (15, 11, or 6 years), the child's

  17. LC-MS/MS based proteomic analysis and functional inference of hypothetical proteins in Desulfovibrio vulgaris.

    Science.gov (United States)

    Zhang, Weiwen; Culley, David E; Gritsenko, Marina A; Moore, Ronald J; Nie, Lei; Scholten, Johannes C M; Petritis, Konstantinos; Strittmatter, Eric F; Camp, David G; Smith, Richard D; Brockman, Fred J

    2006-11-03

    High efficiency capillary liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used to examine the proteins extracted from Desulfovibrio vulgaris cells across six treatment conditions. While our previous study provided a proteomic overview of the cellular metabolism based on proteins with known functions [W. Zhang, M.A. Gritsenko, R.J. Moore, D.E. Culley, L. Nie, K. Petritis, E.F. Strittmatter, D.G. Camp II, R.D. Smith, F.J. Brockman, A proteomic view of the metabolism in Desulfovibrio vulgaris determined by liquid chromatography coupled with tandem mass spectrometry, Proteomics 6 (2006) 4286-4299], this study describes the global detection and functional inference for hypothetical D. vulgaris proteins. Using criteria that a given peptide of a protein is identified from at least two out of three independent LC-MS/MS measurements and that for any protein at least two different peptides are identified among the three measurements, 129 open reading frames (ORFs) originally annotated as hypothetical proteins were found to encode expressed proteins. Functional inference for the conserved hypothetical proteins was performed by a combination of several non-homology based methods: genomic context analysis, phylogenomic profiling, and analysis of a combination of experimental information, including peptide detection in cells grown under specific culture conditions and cellular location of the proteins. Using this approach we were able to assign possible functions to 20 conserved hypothetical proteins. This study demonstrated that a combination of proteomics and bioinformatics methodologies can provide verification of the expression of hypothetical proteins and improve genome annotation.

  18. Neurofeedback training for peak performance

    Directory of Open Access Journals (Sweden)

    Marek Graczyk

    2014-11-01

    Full Text Available [b]aim[/b]. One of the applications of the Neurofeedback methodology is peak performance in sport. The protocols of the neurofeedback are usually based on an assessment of the spectral parameters of spontaneous EEG in resting state conditions. The aim of the paper was to study whether the intensive neurofeedback training of a well-functioning Olympic athlete who has lost his performance confidence after injury in sport, could change the brain functioning reflected in changes in spontaneous EEG and event related potentials (ERPs. [b]case study[/b]. The case is presented of an Olympic athlete who has lost his performance confidence after injury in sport. He wanted to resume his activities by means of neurofeedback training. His QEEG/ERP parameters were assessed before and after 4 intensive sessions of neurotherapy. Dramatic and statistically significant changes that could not be explained by error measurement were observed in the patient. [b]conclusion[/b]. Neurofeedback training in the subject under study increased the amplitude of the monitoring component of ERPs generated in the anterior cingulate cortex, accompanied by an increase in beta activity over the medial prefrontal cortex. Taking these changes together, it can be concluded that that even a few sessions of neurofeedback in a high performance brain can significantly activate the prefrontal cortical areas associated with increasing confidence in sport performance.

  19. Peak Detection Using Wavelet Transform

    Directory of Open Access Journals (Sweden)

    Omar Daoud

    2014-07-01

    Full Text Available A new work based-wavelet transform is designed to o vercome one of the main drawbacks that found in the present new technologies. Orthogonal Frequency Divi sion Multiplexing (OFDMis proposed in the literature to enhance the multimedia resolution. Ho wever, the high peak power (PAPR values will obstr uct such achievements. Therefore, a new proposition is found in this work, making use of the wavelet transforms methods, and it is divided into three ma in stages; de-noising stage, thresholding stage and then the replacement stage. In order to check the system stages validity; a mat hematical model has been built and its checked afte r using a MATLAB simulation. A simulated bit error ra te (BER achievement will be compared with our previously published work, where an enhancement fro m 8×10 -1 to be 5×10 -1 is achieved. Moreover, these results will be compared to the work found in the l iterature, where we have accomplished around 27% PAPR extra reduction. As a result, the BER performance has been improved for the same bandwidth occupancy. Moreover and due to the de-noise stage, the verification rate ha s been improved to reach 81%. This is in addition t o the noise immunity enhancement.

  20. Effects of urbanization on peak streamflows in four Connecticut communities, 1980-84

    Science.gov (United States)

    Weiss, L.A.

    1990-01-01

    Ratios of peak flows in urban basins to peak flows in rural basins in Connecticut are about 1.5 to 6.1 for the 2-year flood and 1.1 to 4.3 for the 100-year flood. The lower ratios, in each case, apply where 30% of the area is served by storm sewers, and the higher ratios apply where 90% of the area is served by storm sewers. Peak flows for six small urban streams were determined from rainfall and runoff data collected from 1981 to 1984 and from a distributed-routing rainfall-runoff model that simulated storm runoff for the period 1951-80. Recurrence intervals of the peak flows for these streams and three other urban streams were estimated using the log-Pearson Type III method and compared with peak flows for rural streams that were computed from regression equations. A comparison of the ratios of urban to rural peak flows shows that basins where more than 50% of the area is served by storm sewers have urban to rural ratios that are outside the 95% confidence limits of the rural regression equations. Peak flows for such areas can be adjusted graphically for the effects of urbanization if the streams drain less than 10 sq mi and manmade storage is less than 4.5 million cu ft/sq mi. (USGS)

  1. 100 years of Weyl’s law

    Directory of Open Access Journals (Sweden)

    Victor Ivrii

    2016-08-01

    Full Text Available Abstract We discuss the asymptotics of the eigenvalue counting function for partial differential operators and related expressions paying the most attention to the sharp asymptotics. We consider Weyl asymptotics, asymptotics with Weyl principal parts and correction terms and asymptotics with non-Weyl principal parts. Semiclassical microlocal analysis, propagation of singularities and related dynamics play crucial role. We start from the general theory, then consider Schrödinger and Dirac operators with the strong magnetic field and, finally, applications to the asymptotics of the ground state energy of heavy atoms and molecules with or without a magnetic field.

  2. Dairy innovations over the past 100 Years.

    Science.gov (United States)

    Tunick, Michael H

    2009-09-23

    The dairy industry in the United States has undergone many changes over the past century. Adulteration and contamination of milk were rampant before the passage and enforcement of the Pure Food and Drug Act of 1906, and the introduction and eventual acceptance of certified and pasteurized milk have provided consumers with a consistently safe product. Homogenization and advances in the packaging and transport of milk gradually took hold, improving the milk supply. Other developments included the concentration of milk and whey, lactose-reduced milk, and the popularization of yogurt. Consumers have benefited from advances in butter packaging, low-fat ice cream, cheese manufacture, and yogurt technology, which has helped create the large demand for dairy products in the United States. Current trends and issues, including the increasing popularity of organic and artisanal products and the use of rBST, will shape the future of the dairy industry.

  3. Appraising Schumpeter's "Essence" after 100 years

    DEFF Research Database (Denmark)

    Andersen, Esben Sloth

    by presenting it as only requiring the introduction of innovative entrepreneurs into the set-up of the Walrasian System. Actually, he could easily define the function of his type of entrepreneurs in this manner, but the analysis of the overall process of evolution required a radical reinterpretation...... of the system of general economic equilibrium. He thus made clear that he could not accept the standard interpretation of the quick Walrasian process of adaptation (tâtonnement). Instead, he saw the innovative transformation of routine behaviour as a relatively slow and conflict-ridden process...

  4. Spinoff 2003: 100 Years of Powered Flight

    Science.gov (United States)

    2003-01-01

    Today, NASA continues to reach milestones in space exploration with the Hubble Telescope, Earth-observing systems, the Space Shuttle, the Stardust spacecraft, the Chandra X-Ray Observatory, the International Space Station, the Mars rovers, and experimental research aircraft these are only a few of the many initiatives that have grown out of NASA engineering know-how to drive the Agency s missions. The technical expertise gained from these programs has transferred into partnerships with academia, industry, and other Federal agencies, ensuring America stays capable and competitive. With Spinoff 2003, we once again highlight the many partnerships with U.S. companies that are fulfilling the 1958 Space Act stipulation that NASA s vast body of scientific and technical knowledge also benefit mankind. This year's issue showcases innovations such as the cochlear implant in health and medicine, a cockpit weather system in transportation, and a smoke mask benefiting public safety; many other products are featured in these disciplines, as well as in the additional fields of consumer/home/recreation, environment and resources management, computer technology, and industrial productivity/ manufactacturing technology. Also in this issue, we devote an entire section to NASA s history in the field of flight and showcase NASA s newest enterprise dedicated to education. The Education Enterprise will provide unique teaching and learning experiences for students and teachers at all levels in science, technology, engineering, and mathematics. The Agency also is committed, as never before, to engaging parents and families through NASA s educational resources, content, and opportunities. NASA s catalyst to intensify its focus on teaching and learning springs from our mission statement: to inspire the next generation of explorers as only NASA can.

  5. 100-Year UPS,"Swifter" Olympics

    Institute of Scientific and Technical Information of China (English)

    Guo Yan; Yang Wei

    2007-01-01

    @@ As the official logistics and express delivery sponsor of 2008Beijing Olympics,UPS will manage all logistical operations at the Olympics Test Events(formally known as "Good Luck Beijing Events")and the actual Games through which majority of equipmerit used at the events will flow.

  6. 100 years of international arbitration and adjudication

    National Research Council Canada - National Science Library

    KEITH, Kenneth

    2014-01-01

    ...) - peaceful means of settlement of international disputes - processes for clarification and development of international law - Hague Academy on International Law - arbitration and adjudication within...

  7. After 100 years, is coevolution relevant?

    Science.gov (United States)

    Geral I. McDonald

    2011-01-01

    On the 100th anniversary of the introduction of Cronartium ribicola into western North America, it is fitting to assess the philosophical foundation of plant pathology and forest ecology. We should ask whether this foundation provides sufficient understanding of blister rust, other diseases of North American forests, and general forest ecology to insure the application...

  8. [100 years of the Babinski sign].

    Science.gov (United States)

    Estañol Vidal, B; Huerta Díaz, E; García Ramos, G

    1997-01-01

    In 1896 Joseph Francois Felix Babinski described for the first time the phenomenon of the toes. In his first paper he simply described extension of all toes with noxious stimulation of the sole of the foot. It was not until 1898 that he specifically described the extension of the hallux with stimulation of the lateral border of the sole. Babinski was probably not aware at the time that E. Remak, a German physician, had previously described the sign. In his third paper of 1903 Babinski concludes that if other authors had described the abnormal reflex before him, they found it fortuitously and did not realize its semiologic value. Babinski probably discovered it by a combination of chance, careful observation and intuition. He also had in mind practical applications of the sign particularly in the differential diagnosis with hysteria and in medico-legal areas. Several of his observations and the physiopathological mechanism proposed by him are still valid today. He realized since 1896 that the Babinski reflex was part of the flexor reflex synergy. He observed that several patients during the first hours of an acute cerebral or spinal insult had absent extensor reflexes. He realized that most patients with the abnormal reflex had weakness of the toes and ankles. He found a lack of correlation between hyperactive myotatic reflexes and the presence of an upgoing hallux. He discovered that not all patients with hemiplegia or paraplegia had the sign. He thought erroneously that some normal subjects could have an upgoing toe. His dream of a practical application of the sign has been fully achieved. The motto of Babinski was Observatio summa lex. Perhaps there is no better dictum in clinical neurology.

  9. Appraising Schumpeter's "Essence" after 100 years

    DEFF Research Database (Denmark)

    Andersen, Esben Sloth

    by presenting it as only requiring the introduction of innovative entrepreneurs into the set-up of the Walrasian System. Actually, he could easily define the function of his type of entrepreneurs in this manner, but the analysis of the overall process of evolution required a radical reinterpretation...

  10. Analysis of 100 Years of Curriculum Designs

    Science.gov (United States)

    Kelting-Gibson, Lynn

    2013-01-01

    Fifteen historical and contemporary curriculum designs were analyzed for elements of assessment that support student learning and inform instructional decisions. Educational researchers are purposely paying attention to the role assessment plays in a well-designed planning and teaching process. Assessment is a vital component to educational…

  11. Lurpak: Ready for another 100 years?

    DEFF Research Database (Denmark)

    Grunert, Klaus G.

    2001-01-01

    The Lur mark - the forerunner and very foundation of Lurpak butter - celebrates its 100th anniversary this year. That is an unusual and impressive lifetime for a consumer goods brand and something Danish dairy sector can be proud of.......The Lur mark - the forerunner and very foundation of Lurpak butter - celebrates its 100th anniversary this year. That is an unusual and impressive lifetime for a consumer goods brand and something Danish dairy sector can be proud of....

  12. The 100 year DASCH Transient Search

    Science.gov (United States)

    Miller, George F.; Grindlay, J. E.; Tang, S.; Los, E.

    2014-01-01

    The Digital Access to a Sky Century at Harvard (DASCH) project is currently digitizing the roughly 500,000 photographic plates maintained by the Harvard College Observatory. The Harvard plate collection covers each point of the sky roughly 500 to 3000 times from 1885 to 1992, with limiting magnitudes ranging from B=14-18 mag and photometric accuracy within ±0.1 mag. Production scanning (up to 400 plates/day) is proceeding in Galactic coordinates from the North Galactic Pole and is currently at roughly 50 degrees galactic latitude. The vastness of these data makes the DASCH project ideal to search for transient behavior. In particular, the large time base of the DASCH collection gives an unprecedented advantage when searching for outbursting systems with recurrence rates of decades or longer. These include recurrent novae, rare WZ Sge Cataclysmic Variables, blazars, X-Ray binaries, and supernovae in the Virgo Supercluster. We report here the discovery of previously unidentified stellar-like objects that underwent abnormally large (Δm=5-9) outbursts discovered with DASCH. We also report the discovery of outbursts from previously quiet AM CVn stars, as well as attempt to characterize their recurrence rates.

  13. 100 years of the physics of diodes

    Science.gov (United States)

    Zhang, Peng; Valfells, Ágúst; Ang, L. K.; Luginsland, J. W.; Lau, Y. Y.

    2017-03-01

    The Child-Langmuir Law (CL), discovered a century ago, gives the maximum current that can be transported across a planar diode in the steady state. As a quintessential example of the impact of space charge shielding near a charged surface, it is central to the studies of high current diodes, such as high power microwave sources, vacuum microelectronics, electron and ion sources, and high current drivers used in high energy density physics experiments. CL remains a touchstone of fundamental sheath physics, including contemporary studies of nanoscale quantum diodes and nano gap based plasmonic devices. Its solid state analog is the Mott-Gurney law, governing the maximum charge injection in solids, such as organic materials and other dielectrics, which is important to energy devices, such as solar cells and light emitting diodes. This paper reviews the important advances in the physics of diodes since the discovery of CL, including virtual cathode formation and extension of CL to multiple dimensions, to the quantum regime, and to ultrafast processes. We review the influence of magnetic fields, multiple species in bipolar flow, electromagnetic and time dependent effects in both short pulse and high frequency THz limits, and single electron regimes. Transitions from various emission mechanisms (thermionic-, field-, and photoemission) to the space charge limited state (CL) will be addressed, especially highlighting the important simulation and experimental developments in selected contemporary areas of study. We stress the fundamental physical links between the physics of beams to limiting currents in other areas, such as low temperature plasmas, laser plasmas, and space propulsion.

  14. Beam Line: 100 years of elementary particles

    Science.gov (United States)

    Pais, A.; Weinberg, S.; Quigg, C.; Riordan, M.; Panofsky, W. K. H.

    1997-04-01

    This issue of Beam Line commemorates the 100th anniversary of the April 30, 1897 report of the discovery of the electron by J.J. Thomson and the ensuing discovery of other subatomic particles. In the first three articles, theorists Abraham Pais, Steven Weinberg, and Chris Quigg provide their perspectives on the discoveries of elementary particles as well as the implications and future directions resulting from these discoveries. In the following three articles, Michael Riordan, Wolfgang Panofsky, and Virginia Trimble apply our knowledge about elementary particles to high-energy research, electronics technology, and understanding the origin and evolution of our Universe.

  15. Leadership: reflections over the past 100 years.

    Science.gov (United States)

    Gregoire, Mary B; Arendt, Susan W

    2014-05-01

    Leadership, viewed by the American Dietetic Association as the ability to inspire and guide others toward building and achieving a shared vision, is a much written-about topic. Research on leadership has addressed the topic using many different approaches, from a very simplistic definition of traits to a more complex process involving interactions, emotions, and learning. Thousands of books and papers have been published on the topic of leadership. This review paper will provide examples of the varying foci of the writings on this topic and includes references for instruments used to measure leadership traits and behaviors. Research is needed to determine effective strategies for preparing dietitians to be effective leaders and assume leadership positions. Identifying ways to help dietitians better reflect on their leadership experiences to enhance their learning and leadership might be one strategy to explore.

  16. Mendelism in human genetics: 100 years on.

    Science.gov (United States)

    Majumdar, Sisir K

    2003-01-01

    Genetics (Greek word--'genes' = born) is a science without an objective past. But the genre of genetics was always roaming in the corridors of human psyche since antiquity. The account of heritable deformities in human often appears in myths and legends. Ancient Hindu Caste system was based on the assumption that both desirable and undesirable traits are passed from generation to generation. In Babylonia 60 birth defects were listed on Clay tablets written around 5,000 year ago. The Jewish Talmud contains accurate description of the inheritance of haemophilia--a human genetic disorder. The Upanisads vedant--800--200 BC provides instructions for the choice of a wife emphasizing that no heritable illness should be present and that the family should show evidence of good character for several preceding generations. These examples indicate that heritable human traits played a significant role in social customs are presented in this article.

  17. Cost-effectiveness models for chronic obstructive pulmonary disease : cross-model comparison of hypothetical treatment scenarios

    NARCIS (Netherlands)

    Hoogendoorn, Martine; Feenstra, Talitha L; Asukai, Yumi; Borg, Sixten; Hansen, Ryan N; Jansson, Sven-Arne; Samyshkin, Yevgeniy; Wacker, Margarethe; Briggs, Andrew H; Lloyd, Adam; Sullivan, Sean D; Rutten-van Mölken, Maureen P M H

    2014-01-01

    OBJECTIVES: To compare different chronic obstructive pulmonary disease (COPD) cost-effectiveness models with respect to structure and input parameters and to cross-validate the models by running the same hypothetical treatment scenarios. METHODS: COPD modeling groups simulated four hypothetical inte

  18. Retro-information in Wheeler-Feynman Universe Model: Applications Over an Hypothetical Concept in Quantum Mechanics

    OpenAIRE

    Jacquet, Philippe; Joly, Véronique

    1998-01-01

    Twisting the non-locality concept in quantum mechanics we introduce the hypothetical concept of retro-information. We analyse the effect of paradoxal coupling on source of retro-information in order to quantify the new means of computing that could be derived from such an hypothetical concept.

  19. Is Silence Golden? Elementary School Teachers' Strategies and Beliefs regarding Hypothetical Shy/Quiet and Exuberant/Talkative Children

    Science.gov (United States)

    Coplan, Robert J.; Hughes, Kathleen; Bosacki, Sandra; Rose-Krasnor, Linda

    2011-01-01

    The primary goal of the present study was to examine elementary teachers' strategies, attitudes, and beliefs regarding hypothetical shy (i.e., quiet), exuberant (i.e., overly talkative), and average (i.e., typical) children. We explored whether these strategies and beliefs varied as a function of the gender of the hypothetical child as well as…

  20. Trends in peak flows of selected streams in Kansas

    Science.gov (United States)

    Rasmussen, T.J.; Perry, C.A.

    2001-01-01

    -flow records containing trends introduce statistical error into flood-frequency analysis. To examine the effect of trends on flood-frequency analysis, statistically significant trends were added systematically to four nontrending station records. Flood magnitudes estimated on the basis of each data series were compared. The added trends resulted in changes in the 100-year flood magnitudes of as much as 70 percent.

  1. Facility Location with Double-peaked Preferences

    DEFF Research Database (Denmark)

    Filos-Ratsikas, Aris; Li, Minming; Zhang, Jie

    2015-01-01

    We study the problem of locating a single facility on a real line based on the reports of self-interested agents, when agents have double-peaked preferences, with the peaks being on opposite sides of their locations. We observe that double-peaked preferences capture real-life scenarios and thus...... complement the well-studied notion of single-peaked preferences. We mainly focus on the case where peaks are equidistant from the agents’ locations and discuss how our results extend to more general settings. We show that most of the results for single-peaked preferences do not directly apply to this setting...

  2. The marginal willingness-to-pay for attributes of a hypothetical HIV vaccine.

    Science.gov (United States)

    Cameron, Michael P; Newman, Peter A; Roungprakhon, Surachet; Scarpa, Riccardo

    2013-08-12

    This paper estimates the marginal willingness-to-pay for attributes of a hypothetical HIV vaccine using discrete choice modeling. We use primary data from 326 respondents from Bangkok and Chiang Mai, Thailand, in 2008-2009, selected using purposive, venue-based sampling across two strata. Participants completed a structured questionnaire and full rank discrete choice modeling task administered using computer-assisted personal interviewing. The choice experiment was used to rank eight hypothetical HIV vaccine scenarios, with each scenario comprising seven attributes (including cost) each of which had two levels. The data were analyzed in two alternative specifications: (1) best-worst; and (2) full-rank, using logit likelihood functions estimated with custom routines in Gauss matrix programming language. In the full-rank specification, all vaccine attributes are significant predictors of probability of vaccine choice. The biomedical attributes of the hypothetical HIV vaccine (efficacy, absence of VISP, absence of side effects, and duration of effect) are the most important attributes for HIV vaccine choice. On average respondents are more than twice as likely to accept a vaccine with 99% efficacy, than a vaccine with 50% efficacy. This translates to a willingness to pay US$383 more for a high efficacy vaccine compared with the low efficacy vaccine. Knowledge of the relative importance of determinants of HIV vaccine acceptability is important to ensure the success of future vaccination programs. Future acceptability studies of hypothetical HIV vaccines should use more finely grained biomedical attributes, and could also improve the external validity of results by including more levels of the cost attribute.

  3. The Ability of Children With Language Impairment to Dissemble Emotions in Hypothetical Scenarios and Natural Situations.

    Science.gov (United States)

    Brinton, Bonnie; Fujiki, Martin; Hurst, Noel Quist; Jones, Emily Rowberry; Spackman, Matthew P

    2015-10-01

    This study examined the ability of children with language impairment (LI) to dissemble (hide) emotional reactions when socially appropriate to do so. Twenty-two children with LI and their typically developing peers (7;1-10;11 [years;months]) participated in two tasks. First, participants were presented with hypothetical scenarios in which the main character was exposed to situations that would require dissembling an emotional reaction for social purposes (e.g., receiving a disappointing gift from a grandparent). In the second task, children were presented with four naturally occurring opportunities to dissemble emotion (e.g., receiving a disappointing reward for taking part in the study). Although the ability to dissemble emotion was still emerging in children in both groups, typically developing children judged that dissemblance was appropriate significantly more often than did children with LI in the hypothetical scenarios. In naturalistic scenarios, there was little difference between groups in low-cost scenarios (those in which the child had nothing to lose by hiding emotion). In the high-cost scenario (hiding emotion meant accepting a disappointing prize), more typically developing children concealed their disappointment than did children with LI. These differences neared statistical significance (p = .058). Children with typically developing language showed a greater ability to dissemble in hypothetical scenarios. In naturalistic scenarios, performance was more nuanced. In low-cost scenarios, there was little difference between groups. In the high-cost scenario, typically developing children tended to dissemble more often than did children with LI.

  4. Parent and medical professional willingness to enroll children in a hypothetical pediatric optic neuritis treatment trial

    Directory of Open Access Journals (Sweden)

    Amy eWaldman

    2011-11-01

    Full Text Available The Optic Neuritis Treatment Trial and subsequent studies have had a tremendous impact on the treatment and prognosis of optic neuritis and multiple sclerosis in adults. The results of these studies have been extrapolated to children; however, pediatric data are sparse. Using the method of prospective preference assessment, the willingness of parents and medical professionals to enroll children in a hypothetical Pediatric Optic Neuritis Treatment Trial was assessed using a mock consent form and questionnaire. A 3-arm trial was proposed: 1 intravenous corticosteroids, 2 high-dose oral corticosteroids, and 3 an oral placebo. The forms were completed by 198 parents and 49 physicians. After reviewing the hypothetical scenario, trial design, risks and benefits, and alternatives to the study, 21% of parents would enroll their children in the trial whereas 98% of medical professionals would enroll their patients. With medical professional recommendation, 43% of parents would enroll their children. The manner in which this hypothetical trial was presented to parents, specifically with respect to the recommendation of their child’s health care team, influenced a parent’s willingness to participate.

  5. In Silico Structural and Functional Annotation of Hypothetical Proteins of Vibrio cholerae O139

    Science.gov (United States)

    Islam, Md. Saiful; Shahik, Shah Md.; Sohel, Md.; Patwary, Noman I. A.

    2015-01-01

    In developing countries threat of cholera is a significant health concern whenever water purification and sewage disposal systems are inadequate. Vibrio cholerae is one of the responsible bacteria involved in cholera disease. The complete genome sequence of V. cholerae deciphers the presence of various genes and hypothetical proteins whose function are not yet understood. Hence analyzing and annotating the structure and function of hypothetical proteins is important for understanding the V. cholerae. V. cholerae O139 is the most common and pathogenic bacterial strain among various V. cholerae strains. In this study sequence of six hypothetical proteins of V. cholerae O139 has been annotated from NCBI. Various computational tools and databases have been used to determine domain family, protein-protein interaction, solubility of protein, ligand binding sites etc. The three dimensional structure of two proteins were modeled and their ligand binding sites were identified. We have found domains and families of only one protein. The analysis revealed that these proteins might have antibiotic resistance activity, DNA breaking-rejoining activity, integrase enzyme activity, restriction endonuclease, etc. Structural prediction of these proteins and detection of binding sites from this study would indicate a potential target aiding docking studies for therapeutic designing against cholera. PMID:26175663

  6. Structural and functional analysis of hypothetical and conserved proteins of Clostridium tetani.

    Science.gov (United States)

    Enany, Shymaa

    2014-01-01

    The progress in biological technologies has led to rapid accumulation of microbial genomic sequences with a vast number of uncharacterized genes. Proteins encoded by these genes are usually uncharacterized, hypothetical, and/or conserved. In Clostridium tetani (C. tetani), these proteins constitute up to 50% of the expressed proteins. In this regard, understanding the functions and the structures of these proteins is crucially important, particularly in C. tetani, which is a medically important pathogen. Here, we used a variety of bioinformatics tools and databases to analyze 10 hypothetical and conserved proteins in C. tetani. We were able to provide a detailed overview of the functional contributions of some of these proteins in several cellular functions, including (1) evolving antibiotic resistance, (2) interaction with enzymes pathways, and (3) involvement in drug transportation. Among these candidates, we postulated the involvement of one of these hypothetical proteins in the pathogenic activity of tetanus. The structural and functional prediction of these proteins should serve in uncovering and better understanding the function of C. tetani cells to ultimately discover new possible drug targets.

  7. Structural engineering developments in power plant cooling tower construction. 100 years of natural draught cooling towers - from tower cooler to cooling tower. Bautechnische Entwicklungen im Kraftwerkskuehlturmbau. 100 Jahre Naturzugkuehltuerme - vom Kaminkuehler zum Kuehlkamin

    Energy Technology Data Exchange (ETDEWEB)

    Damjakob, H.; Depe, T.; Vrangos, V. (Balcke-Duerr AG, Ratingen (Germany))

    1992-06-01

    Almost exactly 100 years ago, tower-type structures were first used for the production of artificial ventilation for cooling purposes. The shell of these so-called tower coolers, today known as 'natural draught cooling towers', was, from the outset, the subject of multiple structural engineering develepments in respect of design, material, construction and statistical calculation. These developments have been stimulated especially by the spasmodic increase in dimensions in the application of power plant cooling towers and, more recently, in connection with ecological requirements. (orig.).

  8. The extreme dry/wet events in northern China during recent 100 years%中国近代北方极端干湿事件的演变规律

    Institute of Scientific and Technical Information of China (English)

    马柱国; 丹利; 胡跃文

    2004-01-01

    Using monthly precipitation and monthly mean temperature, a surface humid index was proposed. According to the index, the distributed characteristics of extreme dryness has been fully analyzed. The results indicated that there is an obvious increasing trend of extreme dryness in the central part of northern China and northeastern China in the last 10 years, which shows a high frequency period of extreme dryness; while a low frequency period in the regions during the last 100 years. Compared with variation trend of the temperature in these regions, the region of high frequent extreme dryness is consistent with the warming trend in the same region.

  9. 27 CFR 9.140 - Atlas Peak.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Atlas Peak. 9.140 Section... THE TREASURY LIQUORS AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.140 Atlas Peak. (a) Name. The name of the viticultural area described in this section is “Atlas Peak.”...

  10. Estimation of peak heat flux onto the targets for CFETR with extended divertor leg

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Chuanjia; Chen, Bin [School of Nuclear Science and Technology, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026 (China); Xing, Zhe [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei, Anhui 230031 (China); Wu, Haosheng [School of Nuclear Science and Technology, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026 (China); Mao, Shifeng, E-mail: sfmao@ustc.edu.cn [School of Nuclear Science and Technology, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026 (China); Luo, Zhengping; Peng, Xuebing [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei, Anhui 230031 (China); Ye, Minyou [School of Nuclear Science and Technology, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026 (China); Institute of Plasma Physics, Chinese Academy of Sciences, Hefei, Anhui 230031 (China)

    2016-11-01

    Highlights: • A hypothetical geometry is assumed to extend the outer divertor leg in CFETR. • Density scan SOLPS simulation is done to study the peak heat flux onto target. • Attached–detached regime transition in out divertor occurs at lower puffing rate. • Unexpected delay of attached–detached regime transition occurs in inner divertor. - Abstract: China Fusion Engineering Test Reactor (CFETR) is now in conceptual design phase. CFETR is proposed as a good complement to ITER for demonstrating of fusion energy. Divertor is a crucial component which faces the plasmas and handles huge heat power for CFETR and future fusion reactor. To explore an effective way for heat exhaust, various methods to reduce the heat flux to divertor target should be considered for CFETR. In this work, the effect of extended out divertor leg on the peak heat flux is studied. The magnetic configuration of the long leg divertor is obtained by EFIT and Tokamak Simulation Code (TSC), while a hypothetical geometry is assumed to extend the out divertor leg as long as possible inside vacuum vessel. A SOLPS simulation is performed to study peak heat flux of the long leg divertor for CFETR. D{sub 2} gas puffing is used and increasing of the puffing rate means increase of plasma density. Both peak heat flux onto inner and outer targets are below 10 MW/m{sup 2} is achieved. A comparison between the peak heat flux between long leg and conventional divertor shows that an attached–detached regime transition of out divertor occurs at lower gas puffing gas puffing rate for long leg divertor. While for the inner divertor, even the configuration is almost the same, the situation is opposite.

  11. On the trail of double peak hydrographs

    Science.gov (United States)

    Martínez-Carreras, Núria; Hissler, Christophe; Gourdol, Laurent; Klaus, Julian; Juilleret, Jérôme; François Iffly, Jean; McDonnell, Jeffrey J.; Pfister, Laurent

    2016-04-01

    A double peak hydrograph features two peaks as a response to a unique rainfall pulse. The first peak occurs at the same time or shortly after the precipitation has started and it corresponds to a fast catchment response to precipitation. The delayed peak normally starts during the recession of the first peak, when the precipitation has already ceased. Double peak hydrographs may occur for various reasons. They can occur (i) in large catchments when lag times in tributary responses are large, (ii) in urban catchments where the first peak is often caused by direct surface runoff on impervious land cover, and the delayed peak to slower subsurface flow, and (iii) in non-urban catchments, where the first and the delayed discharge peaks are explained by different runoff mechanisms (e.g. overland flow, subsurface flow and/or deep groundwater flow) that have different response times. Here we focus on the third case, as a formal description of the different hydrological mechanisms explaining these complex hydrological dynamics across catchments with diverse physiographic characteristics is still needed. Based on a review of studies documenting double peak events we have established a formal classification of catchments presenting double peak events based on their regolith structure (geological substratum and/or its weathered products). We describe the different hydrological mechanisms that trigger these complex hydrological dynamics across each catchment type. We then use hydrometric time series of precipitation, runoff, soil moisture and groundwater levels collected in the Weierbach (0.46 km2) headwater catchment (Luxembourg) to better understand double peak hydrograph generation. Specifically, we aim to find out (1) if the generation of a double peak hydrograph is a threshold process, (2) if the hysteretic relationships between storage and discharge are consistent during single and double peak hydrographs, and (3) if different functional landscape units (the hillslopes

  12. Feasibility Analysis and Simulation of Integrated Renewable Energy System for Power Generation: A Hypothetical Study of Rural Health Clinic

    Directory of Open Access Journals (Sweden)

    Vincent Anayochukwu Ani

    2015-01-01

    Full Text Available This paper presents the feasibility analysis and study of integrated renewable energy (IRE using solar photovoltaic (PV and wind turbine (WT system in a hypothetical study of rural health clinic in Borno State, Nigeria. Electrical power consumption and metrology data (such as solar radiation and wind speed were used for designing and analyzing the integrated renewable energy system. The health clinic facility energy consumption is 19 kWh/day with a 3.4 kW peak demand load. The metrological data was collected from National Aeronautics and Space Administration (NASA website and used to analyze the performance of electrical generation system using HOMER program. The simulation and optimization results show that the optimal integrated renewable energy system configuration consists of 5 kW PV array, BWC Excel-R 7.5 kW DC wind turbine, 24 unit Surrette 6CS25P battery cycle charging, and a 19 kW AC/DC converter and that the PV power can generate electricity at 9,138 kWh/year while the wind turbine system can generate electricity at 7,490 kWh/year, giving the total electrical generation of the system as 16,628 kWh/year. This would be suitable for deployment of 100% clean energy for uninterruptable power performance in the health clinic. The economics analysis result found that the integrated renewable system has total NPC of 137,139 US Dollar. The results of this research show that, with a low energy health facility, it is possible to meet the entire annual energy demand of a health clinic solely through a stand-alone integrated renewable PV/wind energy supply.

  13. Sensitivity Analysis of Evacuation Speed in Hypothetical NPP Accident by Earthquake

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung-yeop; Lim, Ho-Gon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    Effective emergency response in emergency situation of nuclear power plant (NPP) can make consequences be different therefore it is regarded important when establishing an emergency response plan and assessing the risk of hypothetical NPP accident. Situation of emergency response can be totally changed when NPP accident caused by earthquake or tsunami is considered due to the failure of roads and buildings by the disaster. In this study evacuation speed has been focused among above various factors and reasonable evacuation speed in earthquake scenario has been investigated. Finally, sensitivity analysis of evacuation speed in hypothetical NPP accident by earthquake has been performed in this study. Evacuation scenario can be entirely different in the situation of seismic hazard and the sensitivity analysis of evacuation speed in hypothetical NPP accident by earthquake has been performed in this study. Various references were investigated and earthquake evacuation model has been developed considering that evacuees may convert their evacuation method from using a vehicle to walking when they face the difficulty of using a vehicle due to intense traffic jam, failure of buildings and roads, and etc. The population dose within 5 km / 30 km have been found to be increased in earthquake situation due to decreased evacuation speed and become 1.5 - 2 times in the severest earthquake evacuation scenario set up in this study. It is not agreed that using same emergency response model which is used for normal evacuation situations when performing level 3 probabilistic safety assessment for earthquake and tsunami event. Investigation of data and sensitivity analysis for constructing differentiated emergency response model in the event of seismic hazard has been carried out in this study.

  14. Comparison of the hypothetical 57Co brachytherapy source with the 192Ir source

    Science.gov (United States)

    Toossi, Mohammad Taghi Bahreyni; Rostami, Atefeh; Khosroabadi, Mohsen; Khademi, Sara; Knaup, Courtney

    2016-01-01

    Aim of the study The 57Co radioisotope has recently been proposed as a hypothetical brachytherapy source due to its high specific activity, appropriate half-life (272 days) and medium energy photons (114.17 keV on average). In this study, Task Group No. 43 dosimetric parameters were calculated and reported for a hypothetical 57Co source. Material and methods A hypothetical 57Co source was simulated in MCNPX, consisting of an active cylinder with 3.5 mm length and 0.6 mm radius encapsulated in a stainless steel capsule. Three photon energies were utilized (136 keV [10.68%], 122 keV [85.60%], 14 keV [9.16%]) for the 57Co source. Air kerma strength, dose rate constant, radial dose function, anisotropy function, and isodose curves for the source were calculated and compared to the corresponding data for a 192Ir source. Results The results are presented as tables and figures. Air kerma strength per 1 mCi activity for the 57Co source was 0.46 cGyh–1 cm 2 mCi–1. The dose rate constant for the 57Co source was determined to be 1.215 cGyh–1U–1. The radial dose function for the 57Co source has an increasing trend due to multiple scattering of low energy photons. The anisotropy function for the 57Co source at various distances from the source is more isotropic than the 192Ir source. Conclusions The 57Co source has advantages over 192Ir due to its lower energy photons, longer half-life, higher dose rate constant and more isotropic anisotropic function. However, the 192Ir source has a higher initial air kerma strength and more uniform radial dose function. These properties make 57Co a suitable source for use in brachytherapy applications. PMID:27688731

  15. [Study on willingness to participate and willingness to pay for hypothetical industrial injury insurance scheme].

    Science.gov (United States)

    Wu, Yuan; Dong, Hengjin; Duan, Shengnan; Liu, Xiaofang; Ye, Chiyu; You, Hua; Hu, Huimei; Wang, Linhao; Zhang, Xing; Wang, Jing

    2014-10-01

    To investigate workers' willingness to participate and wiliness to pay for a hypothetical industrial injury insurance scheme, to analyze the influential factors, and to provide information for policy making of the government. Multistage cluster sampling was used to select subjects: In the first stage, 9 small, medium, orlarge enterprises were selected fromthree cities (counties) in Zhejiang province, China, according to the level of economic development, transportation convenience, and cooperation of government agencies; in the second stage, several workshops were randomly selected from each of the 9 enterprises. Face-to-face interviews among all workers in the workshops were conducted by trained interviewers using a pre-designed questionnaire. It was found that 73.87% (2095) of all workers were willing to participate in the hypothetical work injury insurance scheme and to pay 2.21% of monthly wage (51.77 yuan) on average, and more than half of the workers were willing to pay less than 1%of monthly wage (35 yuan). Of the 741 workers who were not willing to participate, 327 thought that the premium should be borne by the state or enterprises, instead of individuals, and others were not willing to participate because of low income, unstable job, or poor understanding of the hypothetical industrial injury insurance scheme. Logistic regression analysis showed that workers with higher education levels, longer length of services, longer weekly working time, or more knowledge of occupational diseases showed higher willingness to participate in the scheme; workers who were exposed to physical hazards, had health records, or had participated in the existing medical insurance or industrial injury insurance were more willing to participate. Multiple linear regression analysis showed that with increasing average monthly wage, weekly working time, and self?health evaluation, the proportion of workers with willingness to pay increased; however, with increasing work intensity and

  16. The Use of the Lexical Exponents of Hypothetical Modality in Polish and Lithuanian

    Directory of Open Access Journals (Sweden)

    Danuta Roszko

    2016-12-01

    Full Text Available The Use of the Lexical Exponents of Hypothetical Modality in Polish and Lithuanian In this article the author focuses on the issue of hypothetical modality[1] in Polish and Lithuanian. A list of the basic exponents of hypothetical modality in both languages is presented. However, the focus is mainly placed on the lexical exponents. On the basis of one of the six groups, which describes a high degree of probability (H5, the differences between the use of the lexical exponents in both languages are examined. In the study, multilingual corpora resources, including The Polish-Lithuanian parallel corpus Clarin-PL., are utilized. [1] [In the academic literature, for the notion described herein, the term of epistemic modality is also used.  Nevertheless, in this paper I will continue to use the term of hypotheticality, which I borrowed from the studies on modality, conducted in Polish-Bulgarian cooperation (Slavic Institute of Polish Academy of Sciences and Institute for Bulgarian Language of the Bulgarian Academy of Sciences.]   O użyciu wykładników leksykalnych modalności hipotetycznej w językach polskim i litewskim W artykule autorka porusza zagadnienie modalności hipotetycznej[1]  w językach polskim i litewskim. Przedstawia wykaz podstawowych wykładników modalności hipotetycznej w obu językach. Główną uwagę skupia jednak na wykładnikach leksykalnych. Na przykładzie jednej z sześciu grup, opisującej wysoki stopień prawdopodobieństwa (H5, omawia różnice użycia wykładników leksykalnych w obu językach. W badaniach wykorzystuje wielojęzyczne zasoby korpusowe, w tym Polsko-litewski korpus równoległy Clarin-PL. [1] [W literaturze przedmiotu na oznaczenie opisywanych tu treści stosowany jest również termin epistemiczności. Niemniej jednak w tej pracy autorka pozostaje przy terminie hipotetyczności, który zapożycza z badań nad modalnością, prowadzonych we współpracy polsko-bułgarskiej (Instytut Slawistyki PAN i

  17. A study on the recriticality possibilities of fast reactor cores after a hypothetical core meltdown accident

    Energy Technology Data Exchange (ETDEWEB)

    Na, Byung Chan; Han, Do Hee; Kim, Young Cheol

    1997-04-01

    The preliminary and parametric sensitivity study on recriticality risk of fast reactor cores after a hypothetical total core meltdown accident was performed. Only the neutronic aspects of the accident was considered for this study, independent of the accident scenario. Estimation was made for the quantities of molten fuel which must be ejected out of the core in order to assure a sub-critical state. Diverse parameters were examined: molten pool type (homogenized or stratified), fuel temperature, conditions of the reactor core, core size (small or large), and fuel type (oxide, nitride, metal) (author). 7 refs.

  18. Ab-initio Study of Known and Hypothetical Metal-Organic Frameworks

    Science.gov (United States)

    Fuentes-Cabrera, Miguel; Nicholson, Don M.

    2004-03-01

    Rosi et al. [1] have found that microporous Metal-Organic Frameworks (MOF) materials are candidates for hydrogen storage applications. In particular, MOF-5 was found to adsorb hydrogen up to 4.5 weight percent at 78 kelvin and 1.0 weight percent at room temperature and pressure of 20 bar. We use ab-initio techniques to investigate hydrogen adsorption, stability, and the electronic properties of known and hypothetical Metal-Organic Frameworks. [1] N.L. Rosi, J. Eckert, M. Eddaoudi, D.T. Vodak, J. Kim, M. O'Keeffe, and O.M. Yaghi

  19. The geomorphic structure of the runoff peak

    Directory of Open Access Journals (Sweden)

    R. Rigon

    2011-06-01

    Full Text Available This paper develops a theoretical framework to investigate the core dependence of peak flows on the geomorphic properties of river basins. Based on the theory of transport by travel times, and simple hydrodynamic characterization of floods, this new framework invokes the linearity and invariance of the hydrologic response to provide analytical and semi-analytical expressions for peak flow, time to peak, and area contributing to the peak runoff. These results are obtained for the case of constant-intensity hyetograph using the Intensity-Duration-Frequency (IDF curves to estimate extreme flow values as a function of the rainfall return period. Results show that, with constant-intensity hyetographs, the time-to-peak is greater than rainfall duration and usually shorter than the basin concentration time. Moreover, the critical storm duration is shown to be independent of rainfall return period as well as the area contributing to the flow peak. The same results are found when the effects of hydrodynamic dispersion are accounted for. Further, it is shown that, when the effects of hydrodynamic dispersion are negligible, the basin area contributing to the peak discharge does not depend on the channel velocity, but is a geomorphic propriety of the basin. As an example this framework is applied to three watersheds. In particular, the runoff peak, the critical rainfall durations and the time to peak are calculated for all links within a network to assess how they increase with basin area.

  20. [A peak recognition algorithm designed for chromatographic peaks of transformer oil].

    Science.gov (United States)

    Ou, Linjun; Cao, Jian

    2014-09-01

    In the field of the chromatographic peak identification of the transformer oil, the traditional first-order derivative requires slope threshold to achieve peak identification. In terms of its shortcomings of low automation and easy distortion, the first-order derivative method was improved by applying the moving average iterative method and the normalized analysis techniques to identify the peaks. Accurate identification of the chromatographic peaks was realized through using multiple iterations of the moving average of signal curves and square wave curves to determine the optimal value of the normalized peak identification parameters, combined with the absolute peak retention times and peak window. The experimental results show that this algorithm can accurately identify the peaks and is not sensitive to the noise, the chromatographic peak width or the peak shape changes. It has strong adaptability to meet the on-site requirements of online monitoring devices of dissolved gases in transformer oil.

  1. Evaluating the impacts of farmers' behaviors on a hypothetical agricultural water market based on double auction

    Science.gov (United States)

    Du, Erhu; Cai, Ximing; Brozović, Nicholas; Minsker, Barbara

    2017-05-01

    Agricultural water markets are considered effective instruments to mitigate the impacts of water scarcity and to increase crop production. However, previous studies have limited understanding of how farmers' behaviors affect the performance of water markets. This study develops an agent-based model to explicitly incorporate farmers' behaviors, namely irrigation behavior (represented by farmers' sensitivity to soil water deficit λ) and bidding behavior (represented by farmers' rent seeking μ and learning rate β), in a hypothetical water market based on a double auction. The model is applied to the Guadalupe River Basin in Texas to simulate a hypothetical agricultural water market under various hydrological conditions. It is found that the joint impacts of the behavioral parameters on the water market are strong and complex. In particular, among the three behavioral parameters, λ affects the water market potential and its impacts on the performance of the water market are significant under most scenarios. The impacts of μ or β on the performance of the water market depend on the other two parameters. The water market could significantly increase crop production only when the following conditions are satisfied: (1) λ is small and (2) μ is small and/or β is large. The first condition requires efficient irrigation scheduling, and the second requires well-developed water market institutions that provide incentives to bid true valuation of water permits.

  2. Women's Behavioral Responses to the Threat of a Hypothetical Date Rape Stimulus: A Qualitative Analysis.

    Science.gov (United States)

    Anderson, RaeAnn E; Brouwer, Amanda M; Wendorf, Angela R; Cahill, Shawn P

    2016-05-01

    One in four college women experience sexual assault on campus; yet, campuses rarely provide the in-depth self-defense programs needed to reduce sexual assault risk. Further, little is known about the range of possible behaviors elicited by sexual assault threat stimuli besides assertion. To fill this gap, the aim of the current study was to explore qualitative themes in women's intended behavioral responses to a hypothetical sexual assault threat, date rape, by using a laboratory-controlled threat. College women (N = 139) were randomly assigned to one of four different levels of sexual assault threat presented via an audio-recorded vignette. Participants articulated how they would hypothetically respond to the experimentally assigned threat. Responses were blinded and analyzed using Consensual Qualitative Research methodology. Six major themes emerged: assertion, compliance/acceptance, conditional decision making, avoidance, expressions of discomfort, and allusion to future contact. Although almost all participants described assertion, a number of non-assertive responses were described that are not currently recognized in the literature. These non-assertive responses, including compliance/acceptance, conditional decision making, and avoidance, may represent unique behavioral response styles and likely reflect the complex psychological process of behavioral response to threat. The variety of themes found illustrates the great range of behavioral responses to threat. This broad range is not currently well represented or measured in the literature and better understanding of these responses can inform future interventions, advocacy efforts, and policies focused on sexual assault.

  3. Evaluation of the Thermal Response of the 5-DHLWaste Package-Hypothetical Fire Accident

    Energy Technology Data Exchange (ETDEWEB)

    R.W. Moore

    2001-11-03

    The purpose of this calculation is to determine the thermal response of the 5-defense high level waste (DHLW)/Department of Energy (DOE) codisposal waste package (WP) to the hypothetical fire accident. The objective is to calculate the temperature response of the DHLW glass to the hypothetical short-term fire defined in 10 CFR 71, Section 73(c)(4), Reference 1. The scope of the calculation includes evaluation of the accident with the waste package above ground, at the Yucca Mountain surface facility. The scope is intended to cover a DHLW WP. This WP is loaded with DHLW canisters containing glass from the Savannah River Site (SRS) and a DOE canister containing Training, Research, and Isotope General Atomics (TRIGA) spent nuclear fuel (SNF). The information provided by the sketches attached to this calculation is that for the potential design of the type of WP considered in this calculation. In addition to the nominal design configuration thermal load case, the effects of varying the central DOE canister and DHLW thermal loads are determined. Also, the effects of varying values of the flame and WP outer surface emissivities are evaluated.

  4. OPPORTUNITY COSTS OF REWARD DELAYS AND THE DISCOUNTING OF HYPOTHETICAL MONEY AND CIGARETTES

    Science.gov (United States)

    Johnson, Patrick S.; Herrmann, Evan S.; Johnson, Matthew W.

    2015-01-01

    Humans are reported to discount delayed rewards at lower rates than nonhumans. However, nonhumans are studied in tasks that restrict reinforcement during delays, whereas humans are typically studied in tasks that do not restrict reinforcement during delays. In nonhuman tasks, the opportunity cost of restricted reinforcement during delays may increase delay discounting rates. The present within-subjects study used online crowdsourcing (Amazon Mechanical Turk, or MTurk) to assess the discounting of hypothetical delayed money (and cigarettes in smokers) under four hypothetical framing conditions differing in the availability of reinforcement during delays. At one extreme, participants were free to leave their computer without returning, and engage in any behavior during reward delays (modeling typical human tasks). At the opposite extreme, participants were required to stay at their computer and engage in little other behavior during reward delays (modeling typical nonhuman tasks). Discounting rates increased as an orderly function of opportunity cost. Results also indicated predominantly hyperbolic discounting, the “magnitude effect,” steeper discounting of cigarettes than money, and positive correlations between discounting rates of these commodities. This is the first study to test the effects of opportunity costs on discounting, and suggests that procedural differences may partially account for observed species differences in discounting. PMID:25388973

  5. Potential radiological exposure rates resulting from hypothetical dome failure at Tank W-10

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    The main plant area at Oak Ridge National Laboratory (ORNL) contains 12 buried Gunite tanks that were used for the storage and transfer of liquid radioactive waste. Although the tanks are no longer in use, they are known to contain some residual contaminated sludges and liquids. In the event of an accidental tank dome failure, however unlikely, the liquids, sludges, and radioactive contaminants within the tank walls themselves could create radiation fields and result in above-background exposures to workers nearby. This Technical Memorandum documents a series of calculations to estimate potential radiological exposure rates and total exposures to workers in the event of a hypothetical collapse of a Gunite tank dome. Calculations were performed specifically for tank W-10 because it contains the largest radioactivity inventory (approximately half of the total activity) of all the Gunite tanks. These calculations focus only on external, direct gamma exposures for prescribed, hypothetical exposure scenarios and do not address other possible tank failure modes or routes of exposure. The calculations were performed with established, point-kernel gamma ray modeling codes.

  6. Fluid-structure interaction analysis of a hypothetical core disruptive accident in LMFBRs

    Energy Technology Data Exchange (ETDEWEB)

    Liu Chuang [Department of Engineering Mechanics, Tsinghua University, Beijing 100084 (China)]. E-mail: lch98@mails.tsinghua.edu.cn; Zhang Xiong [Department of Engineering Mechanics, Tsinghua University, Beijing 100084 (China); Lu Mingwan [Department of Engineering Mechanics, Tsinghua University, Beijing 100084 (China)

    2005-03-01

    To ensure safety, it is necessary to assess the integrity of a reactor vessel of liquid-metal fast breeder reactor (LMFBR) under HCDA. Several important problems for a fluid-structural interaction analysis of HCDA are discussed in the present paper. Various loading models of hypothetical core disruptive accident (HCDA) are compared and the polytropic processes of idea gas (PPIG) law is recommended. In order to define a limited total energy release, a '5% truncation criterion' is suggested. The relationship of initial pressure of gas bubble and the total energy release is given. To track the moving interfaces and to avoid the severe mesh distortion an arbitrary Lagrangrian-Eulerian (ALE) approach is adopted in the finite element modeling (FEM) analysis. Liquid separation and splash from a free surface are discussed. By using an elasticity solution under locally uniform pressure, two simplified analytical solutions for 3D and axi-symmetric case of the liquid impact pressure on roof slab are derived. An axi-symmetric finite elements code FRHCDA for fluid-structure interaction analysis of hypothetical core disruptive accident in LMFBR is developed. The CONT benchmark problem is calculated. The numerical results agree well with those from published papers.

  7. Physicians' willingness to grant requests for assistance in dying for children: a study of hypothetical cases.

    Science.gov (United States)

    Vrakking, Astrid M; van der Heide, Agnes; Looman, Caspar W N; van Delden, Johannes J M; Onwuteaka-Philipsen, Bregje D; van der Maas, Paul J; van der Wal, Gerrit

    2005-05-01

    To study the willingness of Dutch physicians to use potentially life-shortening or lethal drugs for severely ill children. We asked 63 pediatricians about their approach to 10 hypothetical cases of children with cancer. The age of the child (15, 11, or 6 years), the child's (explicit) request, and the opinion of the parents varied. Two hypothetical cases were also presented to 125 general practitioners and 208 clinical specialists. Most pediatricians were willing to increase morphine in all cases. A total of 48% to 60% of pediatricians were willing to use lethal drugs in children at the child's request, when the parents agreed; when parents requested ending of life of their unconscious child, 37% to 42% of pediatricians were willing; 13% to 28% of pediatricians were willing when parents did not agree with their child's request. General practitioners and clinical specialists were as willing as pediatricians to use lethal drugs at the child's request, but less willing to grant a request of parents for their unconscious child. Many Dutch pediatricians are willing to use potentially life-shortening or lethal drugs for children. The legal limit of 12 years, as the age under which voluntary euthanasia is forbidden, is not fully supported by Dutch physicians.

  8. Do dark matter halos explain lensing peaks?

    Science.gov (United States)

    Zorrilla Matilla, José Manuel; Haiman, Zoltán; Hsu, Daniel; Gupta, Arushi; Petri, Andrea

    2016-10-01

    We have investigated a recently proposed halo-based model, Camelus, for predicting weak-lensing peak counts, and compared its results over a collection of 162 cosmologies with those from N-body simulations. While counts from both models agree for peaks with S /N >1 (where S /N is the ratio of the peak height to the r.m.s. shape noise), we find ≈50 % fewer counts for peaks near S /N =0 and significantly higher counts in the negative S /N tail. Adding shape noise reduces the differences to within 20% for all cosmologies. We also found larger covariances that are more sensitive to cosmological parameters. As a result, credibility regions in the {Ωm,σ8} are ≈30 % larger. Even though the credible contours are commensurate, each model draws its predictive power from different types of peaks. Low peaks, especially those with 2 important cosmological information in N-body data, as shown in previous studies, but Camelus constrains cosmology almost exclusively from high significance peaks (S /N >3 ). Our results confirm the importance of using a cosmology-dependent covariance with at least a 14% improvement in parameter constraints. We identified the covariance estimation as the main driver behind differences in inference, and suggest possible ways to make Camelus even more useful as a highly accurate peak count emulator.

  9. Electrocapillary instability of magnetic fluid peak

    CERN Document Server

    Mkrtchyan, Levon; Dikansky, Yuri

    2013-01-01

    The paper presents an experimental study of the capillary electrostatic instability occurring under effect of a constant electric field on a magnetic fluid individual peak. The peaks under study occur at disintegration of a magnetic fluid layer applied on a flat electrode surface under effect of a perpendicular magnetic field. The electrocapillary instability shows itself as an emission of charged drops jets from the peak point in direction of the opposing electrode. The charged drops emission repeats periodically and results in the peak shape pulsations. It is shown that a magnetic field affects the electrocapillary instability occurrence regularities and can stimulate its development. The critical electric and magnetic field strengths at which the instability occurs have been measured; their dependence on the peak size is shown. The hysteresis in the system has been studied; it consists in that the charged drops emission stops at a lesser electric (or magnetic) field strength than that of the initial occurr...

  10. Providing peak river flow statistics and forecasting in the Niger River basin

    Science.gov (United States)

    Andersson, Jafet C. M.; Ali, Abdou; Arheimer, Berit; Gustafsson, David; Minoungou, Bernard

    2017-08-01

    Flooding is a growing concern in West Africa. Improved quantification of discharge extremes and associated uncertainties is needed to improve infrastructure design, and operational forecasting is needed to provide timely warnings. In this study, we use discharge observations, a hydrological model (Niger-HYPE) and extreme value analysis to estimate peak river flow statistics (e.g. the discharge magnitude with a 100-year return period) across the Niger River basin. To test the model's capacity of predicting peak flows, we compared 30-year maximum discharge and peak flow statistics derived from the model vs. derived from nine observation stations. The results indicate that the model simulates peak discharge reasonably well (on average + 20%). However, the peak flow statistics have a large uncertainty range, which ought to be considered in infrastructure design. We then applied the methodology to derive basin-wide maps of peak flow statistics and their associated uncertainty. The results indicate that the method is applicable across the hydrologically active part of the river basin, and that the uncertainty varies substantially depending on location. Subsequently, we used the most recent bias-corrected climate projections to analyze potential changes in peak flow statistics in a changed climate. The results are generally ambiguous, with consistent changes only in very few areas. To test the forecasting capacity, we ran Niger-HYPE with a combination of meteorological data sets for the 2008 high-flow season and compared with observations. The results indicate reasonable forecasting capacity (on average 17% deviation), but additional years should also be evaluated. We finish by presenting a strategy and pilot project which will develop an operational flood monitoring and forecasting system based in-situ data, earth observations, modelling, and extreme statistics. In this way we aim to build capacity to ultimately improve resilience toward floods, protecting lives and

  11. The Origin of Weak Lensing Convergence Peaks

    CERN Document Server

    Liu, Jia

    2016-01-01

    Weak lensing convergence peaks are a promising tool to probe nonlinear structure evolution at late times, providing additional cosmological information beyond second-order statistics. Previous theoretical and observational studies have shown that the cosmological constraints on $\\Omega_m$ and $\\sigma_8$ are improved by a factor of up to ~ 2 when peak counts and second-order statistics are combined, compared to using the latter alone. We study the origin of lensing peaks using observational data from the 154 deg$^2$ Canada-France-Hawaii Telescope Lensing Survey. We found that while high peaks (with height $\\kappa$ >3.5 $\\sigma_\\kappa$, where $\\sigma_\\kappa$ is the r.m.s. of the convergence $\\kappa$) are typically due to one single massive halo of ~$10^{15}M_\\odot$, low peaks ($\\kappa$ ~ their virial radii), compared with ~0.25 virial radii for halos linked with high peaks, hinting that low peaks are more immune to baryonic processes whose impact is confined to the inner regions of the dark matter halos. Our fi...

  12. 100 years of power plant technology - 100 years of material technology

    Energy Technology Data Exchange (ETDEWEB)

    Schoch, W.

    1983-07-01

    The introduction of the steam turbine required a spasmodic further development of steam boiler technology for the development of new boilers. The difficulties which occurred in this process due to the lack of suitable steels are indicated in this paper. Design and manufacture have nevertheless still not been resolved satisfactorily. With the founding of the VGB the operators endeavoured to find solutions. Further developments up to the technical maturity of our present conventional and nuclear power plant technology are described.

  13. Peak load arrangements : Assessment of Nordel guidelines

    Energy Technology Data Exchange (ETDEWEB)

    2009-07-01

    Two Nordic countries, Sweden and Finland, have legislation that empowers the TSO to acquire designated peak load resources to mitigate the risk for shortage situations during the winter. In Denmark, the system operator procures resources to maintain a satisfactory level of security of supply. In Norway the TSO has set up a Regulation Power Option Market (RKOM) to secure a satisfactory level of operational reserves at all times, also in winter with high load demand. Only the arrangements in Finland and Sweden fall under the heading of Peak Load Arrangements defined in Nordel Guidelines. NordREG has been invited by the Electricity Market Group (EMG) to evaluate Nordel's proposal for 'Guidelines for transitional Peak Load Arrangements'. The EMG has also financed a study made by EC Group to support NordREG in the evaluation of the proposal. The study has been taken into account in NordREG's evaluation. In parallel to the EMG task, the Swedish regulator, the Energy Markets Inspectorate, has been given the task by the Swedish government to investigate a long term solution of the peak load issue. The Swedish and Finnish TSOs have together with Nord Pool Spot worked on finding a harmonized solution for activation of the peak load reserves in the market. An agreement accepted by the relevant authorities was reached in early January 2009, and the arrangement has been implemented since 19th January 2009. NordREG views that the proposed Nordel guidelines have served as a starting point for the presently agreed procedure. However, NordREG does not see any need to further develop the Nordel guidelines for peak load arrangements. NordREG agrees with Nordel that the market should be designed to solve peak load problems through proper incentives to market players. NordREG presumes that the relevant authorities in each country will take decisions on the need for any peak load arrangement to ensure security of supply. NordREG proposes that such decisions should be

  14. Relationship between cooperation in an iterated prisoner's dilemma game and the discounting of hypothetical outcomes.

    Science.gov (United States)

    Yi, Richard; Johnson, Matthew W; Bickel, Warren K

    2005-08-01

    A number of authors have proposed that preference for a larger, delayed reward in delay discounting is similar to cooperation in a repeated prisoner's dilemma game versus tit-for-tat. This proposal was examined by correlating delay-discounting (Experiment 1) and probability-discounting (Experiment 2) rates for hypothetical monetary gains and losses with performance in a repeated prisoner's dilemma game. Correlations between rate of delay discounting (discounting parameters and area under the curve) and proportion of cooperation in the repeated prisoner's dilemma game versus tit-for-tat were significant across three magnitudes, and correlations were generally higher with discounting for losses than with that for gains. As was expected, correlations between rate of delay discounting and performance versus a random strategy in the prisoner's dilemma game were not significant. Correlations between rate of probability-discounting and cooperation rate in a repeated prisoner's dilemma game versus neither a tit-for-tat nor a random strategy were significant.

  15. Hypothetical Outcome Plots Outperform Error Bars and Violin Plots for Inferences about Reliability of Variable Ordering.

    Directory of Open Access Journals (Sweden)

    Jessica Hullman

    Full Text Available Many visual depictions of probability distributions, such as error bars, are difficult for users to accurately interpret. We present and study an alternative representation, Hypothetical Outcome Plots (HOPs, that animates a finite set of individual draws. In contrast to the statistical background required to interpret many static representations of distributions, HOPs require relatively little background knowledge to interpret. Instead, HOPs enables viewers to infer properties of the distribution using mental processes like counting and integration. We conducted an experiment comparing HOPs to error bars and violin plots. With HOPs, people made much more accurate judgments about plots of two and three quantities. Accuracy was similar with all three representations for most questions about distributions of a single quantity.

  16. Positive versus negative framing of a hypothetical infant immunization: the influence of involvement.

    Science.gov (United States)

    Donovan, R J; Jalleh, G

    2000-02-01

    Framing studies dealing with health messages show mixed results, although a tendency in favor of negative framing. Involvement has been hypothesized to account for these conflicting results. The authors selected a realistic issue (immunization of infants) deemed high or low involving depending on the respondent's circumstances: women with an infant or who were pregnant or intending to get pregnant in the next 12 months were deemed to be high involved; women in none of these categories were deemed to be low involved. A convenience sample of adult women was presented with a hypothetical "new" immunization that protected infants against respiratory complaints such as bronchitis and pneumonia Side effects (the common flu) were framed positively (90% chance of no side effects) or negatively (10% chance of side effects). The authors found positive framing to be superior for low-involved respondents, but there was no framing effect for high-involved respondents.

  17. NMR Structure of the hypothetical protein encoded by the YjbJ gene from Escherichia coli

    Energy Technology Data Exchange (ETDEWEB)

    Pineda-Lucena, Antonio; Liao, Jack; Wu, Bin; Yee, Adelinda; Cort, John R.; Kennedy, Michael A.; Edwards, Aled M.; Arrowsmith, Cheryl H.

    2002-06-01

    Here we describe the solution structure of YjbJ (gil418541) as part of a structural proteomics project on the feasibility of the high-throughput generation of samples from Escherichia coli for structural studies. YjbJ is a hypothetical protein from Escherichia coli protein of unknown function. It is conserved, showing significant sequence identity to four predicted prokaryotic proteins, also of unknown function (Figure 1A). These include gil16762921 from Salmonella enterica (S. typhi), gil17938413 from Agrobacterium tumefaciens, gil16265654 from Sinorizhobium meliloti, and gil15599932 from Pseudomona aeruginosa. The structure of YjbJ reveals a new variation of a common motif (four-helix bundle) that could not be predicted from the protein sequence. Although the biochemical function is unknown, the existence of patterns of conserved residues on the protein surface suggest that the fold and function of all these proteins could be similar.

  18. Performance assessment for a hypothetical low-level waste disposal facility

    Energy Technology Data Exchange (ETDEWEB)

    Smith, C.S.; Rohe, M.J.; Ritter, P.D. [and others

    1997-01-01

    Disposing of low-level waste (LLW) is a concern for many states throughout the United States. A common disposal method is below-grade concrete vaults. Performance assessment analyses make predictions of contaminant release, transport, ingestion, inhalation, or other routes of exposure, and the resulting doses for various disposal methods such as the below-grade concrete vaults. Numerous assumptions are required to simplify the processes associated with the disposal facility to make predictions feasible. In general, these assumptions are made conservatively so as to underestimate the performance of the facility. The objective of this report is to describe the methodology used in conducting a performance assessment for a hypothetical waste facility located in the northeastern United States using real data as much as possible. This report consists of the following: (a) a description of the disposal facility and site, (b) methods used to analyze performance of the facility, (c) the results of the analysis, and (d) the conclusions of this study.

  19. Casimir Effect as a Test for Thermal Corrections and Hypothetical Long-Range Interactions

    CERN Document Server

    Klimchitskaya, G L; Fischbach, E; Krause, D E; López, D; Mostepanenko, V M

    2005-01-01

    We have performed a precise experimental determination of the Casimir pressure between two gold-coated parallel plates by means of a micromachined oscillator. In contrast to all previous experiments on the Casimir effect, where a small relative error (varying from 1% to 15%) was achieved only at the shortest separation, our smallest experimental error ($\\sim 0.5$%) is achieved over a wide separation range from 170 nm to 300 nm at 95% confidence. We have formulated a rigorous metrological procedure for the comparison of experiment and theory without resorting to the previously used root-mean-square deviation, which has been criticized in the literature. This enables us to discriminate among different competing theories of the thermal Casimir force, and to resolve a thermodynamic puzzle arising from the application of Lifshitz theory to real metals. Our results lead to a more rigorous approach for obtaining constraints on hypothetical long-range interactions predicted by extra-dimensional physics and other exte...

  20. Comparison of hypothetical and experienced EQ-5D valuations: relative weights of the five dimensions

    DEFF Research Database (Denmark)

    Rand-Hendriksen, K.; Augestad, L. A.; Sønbø Kristiansen, Ivar;

    2012-01-01

    Survey and on HH ratings from the US EQ-5D valuation study conducted in 2001. We then compared patterns in the relative magnitudes of coefficients that corresponded to the five dimensions. Results In the HH model, self-care and pain/discomfort were the most important dimensions, while usual activities......Purpose EQ-5D tariffs are typically based on general population valuations studies, but whether valuations of experienced health (EH) or hypothetical health (HH) are more appropriate is disputed. Previous comparisons of valuations of EH and HH have focused on absolute differences in dimension......-specific regression coefficients. We examined differences in the relative importance attributed to the EQ-5D dimensions between EH and HH valuations of EQ-5D states in the United States. Methods We used the regression model from the US EQ-5D valuation study on EH ratings from the 2000-2003 Medical Expenditure Panel...

  1. Assessment of Loads and Performance of a Containment in a Hypothetical Accident (ALPHA). Facility design report

    Energy Technology Data Exchange (ETDEWEB)

    Yamano, Norihiro; Maruyama, Yu; Kudo, Tamotsu; Moriyama, Kiyofumi; Ito, Hideo; Komori, Keiichi; Sonobe, Hisao; Sugimoto, Jun [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-06-01

    In the ALPHA (Assessment of Loads and Performance of Containment in Hypothetical Accident) program, several tests have been performed to quantitatively evaluate loads to and performance of a containment vessel during a severe accident of a light water reactor. The ALPHA program focuses on investigating leak behavior through the containment vessel, fuel-coolant interaction, molten core-concrete interaction and FP aerosol behavior, which are generally recognized as significant phenomena considered to occur in the containment. In designing the experimental facility, it was considered to simulate appropriately the phenomena mentioned above, and to cover experimental conditions not covered by previous works involving high pressure and temperature. Experiments from the viewpoint of accident management were also included in the scope. The present report describes design specifications, dimensions, instrumentation of the ALPHA facility based on the specific test objectives and procedures. (author)

  2. Hypothetical superparamagnetic magnetometer in a pigeon's upper beak probably does not work.

    Science.gov (United States)

    Jandačka, Petr; Alexa, Petr; Pištora, Jaromír; Trojková, Jana

    2013-04-01

    We reanalysed the role of superparamagnetic magnetite clusters observed in a pigeon's upper beak to decide if this matter can be a component of some sort of pigeon magnetometer for Earth orientation. We investigated the mutual interaction of the magnetite clusters induced by the geomagnetic field. The force sensitivity of the hypothetical magnetometer in a pigeon's upper beak was estimated considering the previously presented threshold magnetic sensitivity of pigeons, measured in electrophysiological and behavioural investigations. The typical intercluster magnetic force seems to be 10(-19)N well above the threshold magnetic sensitivity. To strengthen our results, we measured the magnetic susceptibility of superparamagnetic magnetite using a vibrating sample magnetometer. Finally we performed theoretical kinematic analysis of the motion of magnetite clusters in cell plasma. The results indicate that magnetite clusters, constituted by superparamagnetic nanoparticles and observed in a pigeon's upper beak, may not be a component of a measuring system providing the magnetic map.

  3. Signal coverage approach to the detection probability of hypothetical extraterrestrial emitters in the Milky Way

    Science.gov (United States)

    Grimaldi, Claudio

    2017-04-01

    The lack of evidence for the existence of extraterrestrial life, even the simplest forms of animal life, makes it is difficult to decide whether the search for extraterrestrial intelligence (SETI) is more a high-risk, high-payoff endeavor than a futile attempt. Here we insist that even if extraterrestrial civilizations do exist and communicate, the likelihood of detecting their signals crucially depends on whether the Earth lies within a region of the galaxy covered by such signals. By considering possible populations of independent emitters in the galaxy, we build a statistical model of the domain covered by hypothetical extraterrestrial signals to derive the detection probability that the Earth is within such a domain. We show that for general distributions of the signal longevity and directionality, the mean number of detectable emitters is less than one even for detection probabilities as large as 50%, regardless of the number of emitters in the galaxy.

  4. Hypothetical Outcome Plots Outperform Error Bars and Violin Plots for Inferences about Reliability of Variable Ordering

    Science.gov (United States)

    Hullman, Jessica; Resnick, Paul; Adar, Eytan

    2015-01-01

    Many visual depictions of probability distributions, such as error bars, are difficult for users to accurately interpret. We present and study an alternative representation, Hypothetical Outcome Plots (HOPs), that animates a finite set of individual draws. In contrast to the statistical background required to interpret many static representations of distributions, HOPs require relatively little background knowledge to interpret. Instead, HOPs enables viewers to infer properties of the distribution using mental processes like counting and integration. We conducted an experiment comparing HOPs to error bars and violin plots. With HOPs, people made much more accurate judgments about plots of two and three quantities. Accuracy was similar with all three representations for most questions about distributions of a single quantity. PMID:26571487

  5. Numerical interpretation of the MARA 8 experiment simulating a hypothetical core disruptive accident

    Energy Technology Data Exchange (ETDEWEB)

    Robbe, M.F. E-mail: mfrobbe@cea.fr; Lepareux, M.; Cariou, Y

    2003-03-01

    In the case of a hypothetical core disruptive accident (HCDA) in a liquid metal fast breeder reactor (LMFBR), it is assumed that the core of the nuclear reactor has melted partially and that the chemical interaction between the molten fuel and the liquid sodium has created a high-pressure gas bubble in the core. The violent expansion of this bubble loads and deforms the reactor vessel, thus endangering the safety of the nuclear plant. The experimental test MARA 8 simulates the explosive phenomenon in a mock-up included in a flexible vessel with a flexible roof. This paper presents a numerical simulation of the test and a comparison of the computed results with the experimental results and previous numerical ones.

  6. Performance assessment for a hypothetical low-level waste disposal facility

    Energy Technology Data Exchange (ETDEWEB)

    Smith, C.S.; Rohe, M.J.; Ritter, P.D. [and others

    1997-01-01

    Disposing of low-level waste (LLW) is a concern for many states throughout the United States. A common disposal method is below-grade concrete vaults. Performance assessment analyses make predictions of contaminant release, transport, ingestion, inhalation, or other routes of exposure, and the resulting doses for various disposal methods such as the below-grade concrete vaults. Numerous assumptions are required to simplify the processes associated with the disposal facility to make predictions feasible. In general, these assumptions are made conservatively so as to underestimate the performance of the facility. The objective of this report is to describe the methodology used in conducting a performance assessment for a hypothetical waste facility located in the northeastern United States using real data as much as possible. This report consists of the following: (a) a description of the disposal facility and site, (b) methods used to analyze performance of the facility, (c) the results of the analysis, and (d) the conclusions of this study.

  7. Structure of the hypothetical Mycoplasma protein, MPN555, suggestsa chaperone function

    Energy Technology Data Exchange (ETDEWEB)

    Schulze-Gahmen, Ursula; Aono, Shelly; Chen, Shengfeng; Yokota,Hisao; Kim, Rosalind; Kim, Sung-Hou

    2005-06-15

    The crystal structure of the hypothetical protein MPN555from Mycoplasma pneumoniae (gi pbar 1673958) has been determined to a resolution of 2.8 Angstrom using anomalous diffraction data at the Sepeak wavelength. Structure determination revealed a mostly alpha-helical protein with a three-lobed shape. The three lobes or fingers delineate a central binding groove and additional grooves between lobes 1 and 3, and between lobes 2 and 3. For one of the molecules in the asymmetric unit,the central binding pocket was filled with a peptide from the uncleaved N-terminal affinity tag. The MPN555 structure has structural homology to two bacterial chaperone proteins, SurA and trigger factor from Escherichia coli. The structural data and the homology to other chaperone for MPN555.

  8. A new drug design strategy: Killing drug resistant bacteria by deactivating their hypothetical genes.

    Science.gov (United States)

    Wong, Tit-Yee; Kuo, Jimmy

    2016-10-01

    Despite that a bacterial genome is complicated by large numbers of horizontally transferred (HT) genes and function unknown hypothetical (FUN) genes, the Genic-Transcriptional-Stop-Signals-Ratio (TSSR) of a genome shows that HT and FUN genes are complementary to all other genes in the genome. When HT or certain FUN genes are omitted from the Escherichia coli K-12 genome, its Genomic-TSSR value becomes totally incomparable to other E. coli strains. The Genic-TSSR correlation tree of a pathogen shows that some FUN genes would form a unique cluster. Removing these genes by site-specific mutation or gene-knockout should lead to the demise of this pathogen.

  9. On a hypothetical generational relationship between HCN and constituents of the reductive citric acid cycle.

    Science.gov (United States)

    Eschenmoser, Albert

    2007-04-01

    Encouraged by observations made on the course of reactions the HCN-tetramer can undergo with acetaldehyde, I delineate a constitutional and potentially generational relationship between HCN and those constituents of the reductive citric acid cycle that are direct precursors of amino acids in contemporary metabolism. In this context, the robustness postulate of classical prebiotic chemistry is questioned, and, by an analysis of the (hypothetical) reaction-tree of a stepwise hydrolysis of the HCN-tetramer, it is shown how such a non-robust chemical reaction platform could harbor the potential for the emergence of autocatalytic cycles. It is concluded that the chemistry of HCN should be revisited by focussing on its non-robust parts in order to demonstrate its full potential as one of the possible roots of prebiotic self-organizing chemical processes.

  10. Geologic simulation model for a hypothetical site in the Columbia Plateau. [AEGIS

    Energy Technology Data Exchange (ETDEWEB)

    Petrie, G.M.; Zellmer, J.T.; Lindberg, J.W.; Foley, M.G.

    1981-04-01

    This report describes the structure and operation of the Assessment of Effectiveness of Geologic Isolation Systems (AEGIS) Geologic Simulation Model, a computer simulation model of the geology and hydrology of an area of the Columbia Plateau, Washington. The model is used to study the long-term suitability of the Columbia Plateau Basalts for the storage of nuclear waste in a mined repository. It is also a starting point for analyses of such repositories in other geologic settings. The Geologic Simulation Model will aid in formulating design disruptive sequences (i.e. those to be used for more detailed hydrologic, transport, and dose analyses) from the spectrum of hypothetical geological and hydrological developments that could result in transport of radionuclides out of a repository. Quantitative and auditable execution of this task, however, is impossible without computer simulation. The computer simulation model aids the geoscientist by generating the wide spectrum of possible future evolutionary paths of the areal geology and hydrology, identifying those that may affect the repository integrity. This allows the geoscientist to focus on potentially disruptive processes, or series of events. Eleven separate submodels are used in the simulation portion of the model: Climate, Continental Glaciation, Deformation, Geomorphic Events, Hydrology, Magmatic Events, Meteorite Impact, Sea-Level Fluctuations, Shaft-Seal Failure, Sub-Basalt Basement Faulting, and Undetected Features. Because of the modular construction of the model, each submodel can easily be replaced with an updated or modified version as new information or developments in the state of the art become available. The model simulates the geologic and hydrologic systems of a hypothetical repository site and region for a million years following repository decommissioning. The Geologic Simulation Model operates in both single-run and Monte Carlo modes.

  11. The multiple roles of hypothetical gene BPSS1356 in Burkholderia pseudomallei.

    Directory of Open Access Journals (Sweden)

    Hokchai Yam

    Full Text Available Burkholderia pseudomallei is an opportunistic pathogen and the causative agent of melioidosis. It is able to adapt to harsh environments and can live intracellularly in its infected hosts. In this study, identification of transcriptional factors that associate with the β' subunit (RpoC of RNA polymerase was performed. The N-terminal region of this subunit is known to trigger promoter melting when associated with a sigma factor. A pull-down assay using histidine-tagged B. pseudomallei RpoC N-terminal region as bait showed that a hypothetical protein BPSS1356 was one of the proteins bound. This hypothetical protein is conserved in all B. pseudomallei strains and present only in the Burkholderia genus. A BPSS1356 deletion mutant was generated to investigate its biological function. The mutant strain exhibited reduced biofilm formation and a lower cell density during the stationary phase of growth in LB medium. Electron microscopic analysis revealed that the ΔBPSS1356 mutant cells had a shrunken cytoplasm indicative of cell plasmolysis and a rougher surface when compared to the wild type. An RNA microarray result showed that a total of 63 genes were transcriptionally affected by the BPSS1356 deletion with fold change values of higher than 4. The expression of a group of genes encoding membrane located transporters was concurrently down-regulated in ΔBPSS1356 mutant. Amongst the affected genes, the putative ion transportation genes were the most severely suppressed. Deprivation of BPSS1356 also down-regulated the transcriptions of genes for the arginine deiminase system, glycerol metabolism, type III secretion system cluster 2, cytochrome bd oxidase and arsenic resistance. It is therefore obvious that BPSS1356 plays a multiple regulatory roles on many genes.

  12. Molecular Characterization and Immune Protection of a New Conserved Hypothetical Protein of Eimeria tenella.

    Directory of Open Access Journals (Sweden)

    Qi Zhai

    Full Text Available The genome sequences of Eimeria tenella have been sequenced, but >70% of these genes are currently categorized as having an unknown function or annotated as conserved hypothetical proteins, and few of them have been studied. In the present study, a conserved hypothetical protein gene of E. tenella, designated EtCHP559, was cloned using rapid amplification of cDNA 5'-ends (5'RACE based on the expressed sequence tag (EST. The 1746-bp full-length cDNA of EtCHP559 contained a 1224-bp open reading frame (ORF that encoded a 407-amino acid polypeptide with the predicted molecular weight of 46.04 kDa. Real-time quantitative PCR analysis revealed that EtCHP559 was expressed at higher levels in sporozoites than in the other developmental stages (unsporulated oocysts, sporulated oocysts and second generation merozoites. The ORF was inserted into pCold-TF to produce recombinant EtCHP559. Using western blotting, the recombinant protein was successfully recognized by rabbit serum against E. tenella sporozoites. Immunolocalization by using EtCHP559 antibody showed that EtCHP559 was mainly distributed on the parasite surface in free sporozoites and became concentrated in the anterior region after sporozoites were incubated in complete medium. The EtCHP559 became uniformly dispersed in immature and mature schizonts. Inhibition of EtCHP559 function using anti-rEtCHP559 polyclonal antibody reduced the ability of E. tenella sporozoites to invade host cells by >70%. Animal challenge experiments demonstrated that the recombinant EtCHP559 significantly increased the average body weight gain, reduced the oocyst outputs, alleviated cecal lesions of the infected chickens, and resulted in anticoccidial index >160 against E. tenella. These results suggest that EtCHP559 plays an important role in sporozoite invasion and could be an effective candidate for the development of a new vaccine against E. tenella.

  13. Bayesian peak picking for NMR spectra.

    Science.gov (United States)

    Cheng, Yichen; Gao, Xin; Liang, Faming

    2014-02-01

    Protein structure determination is a very important topic in structural genomics, which helps people to understand varieties of biological functions such as protein-protein interactions, protein-DNA interactions and so on. Nowadays, nuclear magnetic resonance (NMR) has often been used to determine the three-dimensional structures of protein in vivo. This study aims to automate the peak picking step, the most important and tricky step in NMR structure determination. We propose to model the NMR spectrum by a mixture of bivariate Gaussian densities and use the stochastic approximation Monte Carlo algorithm as the computational tool to solve the problem. Under the Bayesian framework, the peak picking problem is casted as a variable selection problem. The proposed method can automatically distinguish true peaks from false ones without preprocessing the data. To the best of our knowledge, this is the first effort in the literature that tackles the peak picking problem for NMR spectrum data using Bayesian method.

  14. Osteoporosis: Peak Bone Mass in Women

    Science.gov (United States)

    ... not supported by your browser. Home Osteoporosis Women Osteoporosis: Peak Bone Mass in Women Publication available in: ... drug products. NIH Pub. No. 15-7891 NIH Osteoporosis and Related Bone Diseases ~ National Resource Center 2 ...

  15. Bayesian Peak Picking for NMR Spectra

    KAUST Repository

    Cheng, Yichen

    2014-02-01

    Protein structure determination is a very important topic in structural genomics, which helps people to understand varieties of biological functions such as protein-protein interactions, protein–DNA interactions and so on. Nowadays, nuclear magnetic resonance (NMR) has often been used to determine the three-dimensional structures of protein in vivo. This study aims to automate the peak picking step, the most important and tricky step in NMR structure determination. We propose to model the NMR spectrum by a mixture of bivariate Gaussian densities and use the stochastic approximation Monte Carlo algorithm as the computational tool to solve the problem. Under the Bayesian framework, the peak picking problem is casted as a variable selection problem. The proposed method can automatically distinguish true peaks from false ones without preprocessing the data. To the best of our knowledge, this is the first effort in the literature that tackles the peak picking problem for NMR spectrum data using Bayesian method.

  16. Amplification of postwildfire peak flow by debris

    Science.gov (United States)

    Kean, J. W.; McGuire, L. A.; Rengers, F. K.; Smith, J. B.; Staley, D. M.

    2016-08-01

    In burned steeplands, the peak depth and discharge of postwildfire runoff can substantially increase from the addition of debris. Yet methods to estimate the increase over water flow are lacking. We quantified the potential amplification of peak stage and discharge using video observations of postwildfire runoff, compiled data on postwildfire peak flow (Qp), and a physically based model. Comparison of flood and debris flow data with similar distributions in drainage area (A) and rainfall intensity (I) showed that the median runoff coefficient (C = Qp/AI) of debris flows is 50 times greater than that of floods. The striking increase in Qp can be explained using a fully predictive model that describes the additional flow resistance caused by the emergence of coarse-grained surge fronts. The model provides estimates of the amplification of peak depth, discharge, and shear stress needed for assessing postwildfire hazards and constraining models of bedrock incision.

  17. Peak Vegetation Growth 2000 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 2000 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  18. Peak Vegetation Growth 2004 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 2004 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  19. Peak Vegetation Growth 1999 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1999 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  20. Peak Vegetation Growth 1993 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1993 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  1. Peak Vegetation Growth 1994 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1994 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  2. Peak Vegetation Growth 1995 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1995 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  3. Peak Vegetation Growth 1998 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1998 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  4. Peak Vegetation Growth 2001 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 2001 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  5. Peak Vegetation Growth 2003 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 2003 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  6. Peak Vegetation Growth 1997 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1997 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  7. Peak Vegetation Growth 1990 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1990 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  8. Peak Vegetation Growth 1996 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1996 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  9. Peak Vegetation Growth 2005 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 2005 peak vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the map...

  10. Tectonics, Climate and Earth's highest peaks

    Science.gov (United States)

    Robl, Jörg; Prasicek, Günther; Hergarten, Stefan

    2016-04-01

    Prominent peaks characterized by high relief and steep slopes are among the most spectacular morphological features on Earth. In collisional orogens they result from the interplay of tectonically driven crustal thickening and climatically induced destruction of overthickened crust by erosional surface processes. The glacial buzz-saw hypothesis proposes a superior status of climate in limiting mountain relief and peak altitude due to glacial erosion. It implies that peak altitude declines with duration of glacial occupation, i.e., towards high latitudes. This is in strong contrast with high peaks existing in high latitude mountain ranges (e.g. Mt. St. Elias range) and the idea of peak uplift due to isostatic compensation of spatially variable erosional unloading an over-thickened orogenic crust. In this study we investigate landscape dissection, crustal thickness and vertical strain rates in tectonically active mountain ranges to evaluate the influence of erosion on (latitudinal) variations in peak altitude. We analyze the spatial distribution of serval thousand prominent peaks on Earth extracted from the global ETOPO1 digital elevation model with a novel numerical tool. We compare this dataset to crustal thickness, thickening rate (vertical strain rate) and mean elevation. We use the ratios of mean elevation to peak elevation (landscape dissection) and peak elevation to crustal thickness (long-term impact of erosion on crustal thickness) as indicators for the influence of erosional surface processes on peak uplift and the vertical strain rate as a proxy for the mechanical state of the orogen. Our analysis reveals that crustal thickness and peak elevation correlate well in orogens that have reached a mechanically limited state (vertical strain rate near zero) where plate convergence is already balanced by lateral extrusion and gravitational collapse and plateaus are formed. On the Tibetan Plateau crustal thickness serves to predict peak elevation up to an altitude

  11. Cosmic Microwave Background Acoustic Peak Locations

    CERN Document Server

    Pan, Zhen; Mulroe, Brigid; Narimani, Ali

    2016-01-01

    The Planck collaboration has measured the temperature and polarization of the cosmic microwave background well enough to determine the locations of eight peaks in the temperature (TT) power spectrum, five peaks in the polarization (EE) power spectrum and twelve extrema in the cross (TE) power spectrum. The relative locations of these extrema give a striking, and beautiful, demonstration of what we expect from acoustic oscillations in the plasma; e.g., that EE peaks fall half way between TT peaks. We expect this because the temperature map is predominantly sourced by temperature variations in the last scattering surface, while the polarization map is predominantly sourced by gradients in the velocity field, and the harmonic oscillations have temperature and velocity 90 degrees out of phase. However, there are large differences in expectations for extrema locations from simple analytic models vs. numerical calculations. Here we quantitatively explore the origin of these differences in gravitational potential tr...

  12. A summary review of the photos of the ethnic groups in Yunnan in the past 100 years%云南百年民族题材照片的人类学解读

    Institute of Scientific and Technical Information of China (English)

    尹绍亭

    2015-01-01

    This paper gives a comprehensive review of the photos of the ethnic groups in Yunnan taken by Chinese and international ethnologists and anthropologists in the past 100 years.These pho-tos are divided into three historical periods according to their characteristics.The paper discusses the theoretical orientations,cultural implications as well as the value,significance and weaknesses of these photos as precious data of visual anthropology.%本文系统地梳理回顾了中外人类学民族学者百年来所拍摄的云南田野照片。根据拍摄时代和资料的特征,笔者将照片分为三个阶段,并逐一讨论各阶段照片资料的理论取向和文化内涵,表现了作为影视人类学重要途径的照片拍摄研究的价值、意义以及存在的问题。

  13. 1,3:2,4-Dibenzylidene-D-sorbitol (DBS) and its derivatives--efficient, versatile and industrially-relevant low-molecular-weight gelators with over 100 years of history and a bright future.

    Science.gov (United States)

    Okesola, Babatunde O; Vieira, Vânia M P; Cornwell, Daniel J; Whitelaw, Nicole K; Smith, David K

    2015-06-28

    Dibenzylidene-D-sorbitol (DBS) has been a well-known low-molecular-weight gelator of organic solvents for over 100 years. As such, it constitutes a very early example of a supramolecular gel--a research field which has recently developed into one of intense interest. The ability of DBS to self-assemble into sample-spanning networks in numerous solvents is predicated upon its 'butterfly-like' structure, whereby the benzylidene groups constitute the 'wings' and the sorbitol backbone the 'body'--the two parts representing the molecular recognition motifs underpinning its gelation mechanism, with the nature of solvent playing a key role in controlling the precise assembly mode. This gelator has found widespread applications in areas as diverse as personal care products and polymer nucleation/clarification, and has considerable potential in applications such as dental composites, energy technology and liquid crystalline materials. Some derivatives of DBS have also been reported which offer the potential to expand the scope and range of applications of this family of gelators and endow the nansocale network with additional functionality. This review aims to explain current trends in DBS research, and provide insight into how by combining a long history of application, with modern methods of derivatisation and analysis, the future for this family of gelators is bright, with an increasing number of high-tech applications, from environmental remediation to tissue engineering, being within reach.

  14. Bank erosion history of a mountain stream determined by means of anatomical changes in exposed tree roots over the last 100 years (Bílá Opava River — Czech Republic)

    Science.gov (United States)

    Malik, Ireneusz; Matyja, Marcin

    2008-06-01

    The date of exposure of spruce roots as a result of bank erosion was investigated on the Bílá Opava River in the northeastern Czech Republic. Following the exposure of roots, wood cells in the tree rings divide into early wood and late wood. Root cells within the tree rings also become smaller and more numerous. These processes permit dating of the erosion episodes in which roots were exposed. Sixty root samples were taken from seven sampling sites selected on two riverbed reaches. The results of root exposure dating were compared to historical data on hydrological flooding. Using the root exposure dating method, several erosion episodes were recorded for the last 100 years. The greatest bank erosion was recorded as consequence of an extraordinary flood in July 1997. In the upper, rocky part of the valley studied, bank erosion often took place during large floods that occurred in the early 20th century. In the lower, alluvial part of the valley, erosion in the exposed roots was recorded only in 1973 and has been intensive ever since. It is suggested that banks in the lower part are more frequently undercut, which leads to the falling of trees within whose roots older erosion episodes were recorded. Locally, bank erosion is often intensified by the position of 1- to 2-m boulders in the riverbed, which direct water into the parts of the banks where erosion occurs. Selective bank erosion could be intensified by debris dams and hillslope material supply to the riverbed.

  15. Application of a stent splint to protect intraoral organs from radiation injury to a 97 year-old patient with multiple oral cancers who survived over 100 year-old

    Energy Technology Data Exchange (ETDEWEB)

    Yanagisawa, Shigetaka; Kawamura, Tetsuo; Shimizu, Masatsugu; Aoki, Hirooki; Mizuki, Harumi; Ashizawa, Akira (Oita Medical Coll., Hasama (Japan))

    1989-06-01

    Radiation therapy had been used with increasing frequency in recent years in the management of oral cancers of advanced ages. In those cases we have to take good care to maintain the oral health of patients undergoing cancerocidal dose of radiation therapy. Using splints, as a tissue displacer, during radiation, we could treat a 99-year-old female patient without serious radiation sequelae, successfully she survived over 100 year-old. As she visited us at 97 year-old, the primary lesions located on the left upper lip, nose, upper and lower gums were diagnosed as multiple verrucous carcinoma histologically. Seventeen months after the first radiotherapy to the lip, nose and upper jaw, we planned again radiotherapy to the recurrent tumor of the lower gum. In order to eliminate and minimize side effects of the second irradiation for the contigenous intraoral organs, we devised a splint to exclude the tongue and upper gum apart from a radiation field. The splint, as tissue displacer, was made of heat-cured acrylic resin and divided into two pieces which were formed like full denture without artificial teeth. They were applied to the upper and lower jaws. The lower one had a large wing to exclude the tongue from irradiation field. After setting of the splint, she had been clenched slightly with an aid of chin cap. Then we could finish successfully the radiotherapy with 10 MV X-ray 40 Gy as scheduled without serious troubles. (author).

  16. Review and Preview on The Development of the World women's 100 m Running in Nearly 100 Years%世界女子百米短跑百年发展的回顾与前瞻

    Institute of Scientific and Technical Information of China (English)

    王刚; 辛飞庆; 辛飞兵

    2014-01-01

    为了解和掌握近百年来世界女子百米短跑变化状况,运用文献资料法、数理统计法和比较法,分析世界女子百米短跑发展趋势,旨在探索当今及未来世界女子百米短跑发展趋势。结论:奥运会女子纪录不断被刷新,美国女子百米仍处世界领先水平,夺取奥运女子百米桂冠黑人选手居多,女性的生理结构决定女子百米成绩已达到女子极限。%This paper aims to understand and grasp the changes of the world women's 100 m running in nearly 100 years, explores the current and future development trend of world women's 100m running by methods of literature material , mathematical statistics and comparative law.Results show that the Olym-pic Games women's record has been refreshed on and on , the United States sprinters are still leading in the world, black sprinters is in the majority seizing the best title of Olympic games , the performance has reached the limit determined by the physiological structure of the female.

  17. Do dark matter halos explain lensing peaks?

    CERN Document Server

    Matilla, José Manuel Zorrilla; Hsu, Daniel; Gupta, Arushi; Petri, Andrea

    2016-01-01

    We have investigated a recently proposed halo-based model, Camelus, for predicting weak-lensing peak counts, and compared its results over a collection of 162 cosmologies with those from N-body simulations. While counts from both models agree for peaks with $\\mathcal{S/N}>1$ (where $\\mathcal{S/N}$ is the ratio of the peak height to the r.m.s. shape noise), we find $\\approx 50\\%$ fewer counts for peaks near $\\mathcal{S/N}=0$ and significantly higher counts in the negative $\\mathcal{S/N}$ tail. Adding shape noise reduces the differences to within $20\\%$ for all cosmologies. We also found larger covariances that are more sensitive to cosmological parameters. As a result, credibility regions in the $\\{\\Omega_m, \\sigma_8\\}$ are $\\approx 30\\%$ larger. Even though the credible contours are commensurate, each model draws its predictive power from different types of peaks. Low peaks, especially those with $23)$. Our results confirm the importance of using a cosmology-dependent covariance with at least a 14\\% improveme...

  18. Probable hydrologic effects of a hypothetical failure of Mackay Dam on the Big Lost River Valley from Mackay, Idaho to the Idaho National Engineering Laboratory

    Science.gov (United States)

    Druffel, Leroy; Stiltner, Gloria J.; Keefer, Thomas N.

    1979-01-01

    Mackay Dam is an irrigation reservoir on the Big Lost River, Idaho, approximately 7.2 kilometers northwest of Mackay, Idaho. Consequences of possible rupture of the dam have long concerned the residents of the river valley. The presence of reactors and of a management complex for nuclear wastes on the reservation of the Idaho National Engineering Laboratory (INEL), near the river , give additional cause for concern over the consequences of a rupture of Mackay Dam. The objective of this report is to calculate and route the flood wave resulting from the hypothetical failure of Mackay Dam downstream to the INEL. Both a full and a 50 percent partial breach of this dam are investigated. Two techniques are used to develop the dam-break model. The method of characteristics is used to propagate the shock wave after the dam fails. The linear implicit finite-difference solution is used to route the flood wave after the shock wave has dissipated. The time of travel of the flood wave, duration of flooding, and magnitude of the flood are determined for eight selected sites from Mackay Dam, Idaho, through the INEL diversion. At 4.2 kilometers above the INEL diversion, peak discharges of 1,550.2 and 1,275 cubic meters per second and peak flood elevations of 1,550.3 and 1,550.2 meters were calculated for the full and partial breach, respectively. Flood discharges and flood peaks were not compared for the area downstream of the diversion because of the lack of detailed flood plain geometry. (Kosco-USGS)

  19. Signs of hypothetical flora on the planet venus: Revision of the TV experiment data (1975-1982)

    Science.gov (United States)

    Ksanfomality, L. V.; Selivanov, A. S.; Gektin, Yu. M.; Avanesov, G. A.

    2016-05-01

    Unique archive data from investigations of the surface of Venus performed with television cameras on the VENERA missions in 1975 and 1982 were reprocessed with up-to-date techniques, which substantially improved their level of detail. Numerous objects exhibiting a complex regular structure and presumably very slow motions (in the case of hypothetical fauna) have been found. The objects are noticeable in size and may testify to the existence of life. This paper reviews the results of searching for and identifying hypothetical objects of Venusian flora. The detected and identified hypothetical objects considerably exhaust the corresponding potential of the television images. It is concluded that, to investigate the surface of Venus, a new special mission, much more sophisticated than the VENERA missions (1975-1982), should be urgently carried out.

  20. Flood frequency analysis for nonstationary annual peak records in an urban drainage basin

    Science.gov (United States)

    Villarini, G.; Smith, J.A.; Serinaldi, F.; Bales, J.; Bates, P.D.; Krajewski, W.F.

    2009-01-01

    Flood frequency analysis in urban watersheds is complicated by nonstationarities of annual peak records associated with land use change and evolving urban stormwater infrastructure. In this study, a framework for flood frequency analysis is developed based on the Generalized Additive Models for Location, Scale and Shape parameters (GAMLSS), a tool for modeling time series under nonstationary conditions. GAMLSS is applied to annual maximum peak discharge records for Little Sugar Creek, a highly urbanized watershed which drains the urban core of Charlotte, North Carolina. It is shown that GAMLSS is able to describe the variability in the mean and variance of the annual maximum peak discharge by modeling the parameters of the selected parametric distribution as a smooth function of time via cubic splines. Flood frequency analyses for Little Sugar Creek (at a drainage area of 110 km2) show that the maximum flow with a 0.01-annual probability (corresponding to 100-year flood peak under stationary conditions) over the 83-year record has ranged from a minimum unit discharge of 2.1 m3 s- 1 km- 2 to a maximum of 5.1 m3 s- 1 km- 2. An alternative characterization can be made by examining the estimated return interval of the peak discharge that would have an annual exceedance probability of 0.01 under the assumption of stationarity (3.2 m3 s- 1 km- 2). Under nonstationary conditions, alternative definitions of return period should be adapted. Under the GAMLSS model, the return interval of an annual peak discharge of 3.2 m3 s- 1 km- 2 ranges from a maximum value of more than 5000 years in 1957 to a minimum value of almost 8 years for the present time (2007). The GAMLSS framework is also used to examine the links between population trends and flood frequency, as well as trends in annual maximum rainfall. These analyses are used to examine evolving flood frequency over future decades. ?? 2009 Elsevier Ltd.

  1. Behavioral Economics of Cigarette Purchase Tasks: Within-Subject Comparison of Real, Potentially Real, and Hypothetical Cigarettes.

    Science.gov (United States)

    Wilson, A George; Franck, Christopher T; Koffarnus, Mikhail N; Bickel, Warren K

    2016-05-01

    Hypothetical rewards are commonly used in studies of laboratory-based tobacco demand. However, behavioral economic demand procedures require confirmation that the behavior elicited from real and hypothetical reward types are equivalent, and that results attained from these procedures are comparable to other accepted tasks, such as the hypothetical purchase task. Nineteen smokers were asked to purchase 1 week's worth of cigarettes that they would consume over the following week either at one price that incrementally increased across four weekly sessions ("real" sessions) or four prices in a single session ("potentially real" session), one of which was randomly chosen to be actualized. At each session, participants also completed a hypothetical cigarette purchase task. After each week, participants reported the number of cigarettes they actually smoked. Demand was found to be equivalent under both the real and potentially real reward conditions but statistically different from the demand captured in the hypothetical purchase task. However, the amounts purchased at specific prices in the hypothetical purchase task were significantly correlated with the amount purchased at comparable prices in the other two tasks (except for the highest price examined in both tasks of $1.00 per cigarette). Number of cigarettes consumed that were obtained outside of the study was correlated with study cigarette price. Combined, these results suggest that purchasing behavior during potentially real sessions (1) was not functionally different from real sessions, (2) imposes fewer costs to the experimenter, and (3) has high levels of both internal and external validity. © The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  2. An Efficient Method to Design Premature End-of-Life Trajectories: A Hypothetical Alternate Fate for Cassini

    Science.gov (United States)

    Vaquero, Mar; Senent, Juan

    2015-01-01

    What would happen if, hypothetically, the highly successful Cassini mission were to end prematurely due to lack of propellant or sudden subsystem failure? A solid plan to quickly produce a solution for any given scenario, regardless of where the spacecraft is along its reference path, must be in place to safely dispose of the spacecraft and meet all planetary protection requirements. As a contingency plan for this hypothetical situation, a method to design viable high-fidelity terminating trajectories based on a hybrid approach that exploits two-body and three-body flyby transfers combined with a numerical optimization scheme is detailed in this paper.

  3. Simulations of a hypothetical temperature control structure at Detroit Dam on the North Santiam River, northwestern Oregon

    Science.gov (United States)

    Buccola, Norman L.; Stonewall, Adam J.; Rounds, Stewart A.

    2015-01-01

    Water temperature models of Detroit Lake, Big Cliff Lake, and the North Santiam River in northwestern Oregon were used to assess the potential for a hypothetical structure with variable intake elevations and an internal connection to power turbines at Detroit Dam (scenario SlidingWeir) to release more natural, pre-dam temperatures year round. This hypothetical structure improved outflow temperature control from Detroit Dam while meeting minimum dry-season release rates and lake levels specified by the rule curve specified for Detroit Lake.

  4. Investigating a Hypothetical Semiconductor Laser Bar Using a Laser Diode Simulation/Emulation Tool Using Random Levels of Defects

    Directory of Open Access Journals (Sweden)

    C.K. Amuzuvi

    2014-02-01

    Full Text Available In this study, Barlase, a semiconductor laser diode emulation tool, is used to emulate the by-emitter degradation of high power semiconductor laser diodes. Barlase is a software that uses a LabView control interface. We have demonstrated how Barlase works using a hypothetical laser diode bar (multiple emitters to validate the usefulness of the tool. A scenario using the hypothetical bar was investigated to demonstrate Barlase as follows: random low-level of defects distributed across the bar. The results of the simulation show the successful implementation of Barlase in the by-emitter analysis of laser diodes.

  5. Ground-Water Capture Zone Delineation of Hypothetical Systems: Methodology Comparison and Real-World Applications

    Science.gov (United States)

    Ahern, J. A.; Lilly, M. R.; Hinzman, L. D.

    2003-12-01

    A capture zone is the aquifer volume through which ground-water flows to a pumping well over a given time of travel. Determining a well's capture zone aids in water-supply management by creating an awareness of the water source. This helps ensure sustainable pumping operations and outlines areas where protection from contamination is critical. We are delineating the capture zones of hypothetical conceptual models that resemble the Fairbanks, Alaska floodplain both in aquifer parameters and boundary conditions. We begin with a very simple hydrogeologic system and gradually add complexity such as heterogeneity, anisotropy, multiple wells, and zones of permafrost. Commonly-used delineation methods are applied to each case. These include calculated fixed-radius, analytical and numerical models. The calculated fixed-radius method uses a mathematical equation with several simplifying assumptions. Analytical techniques employ a series of equations that likewise assume simple conditions, although to a lesser degree than the fixed-radius method. Our chosen numerical model is MODFLOW-2000, which offers a particle-tracking package (MODPATH) for delineating recharge areas. The delineations are overlayed for each conceptual model in order to compare the capture zones produced by the different methods. Contrasts between capture zones increase with the complexity of the hydrogeology. Simpler methods are restricted by their underlying assumptions. When methods can no longer account for complexities in the conceptual model, the resulting delineations remain similar to those of simpler models. Meanwhile, the zones generated by more sophisticated methods are able to change with changes to the conceptual model. Hence, the simpler methods now lack accuracy and credibility. We have found that these simpler techniques tend to overestimate the capture zone. Water-supply managers must consider such inaccuracies when evaluating the costs of each method. In addition to comparing delineation

  6. 近百年El Nino/La Nina事件与北京气候相关性分析%Correlation Analysis Between El Nino/La Nina Phenomenon During the Recent 100 Years and Beijing Climate

    Institute of Scientific and Technical Information of China (English)

    刘桂莲; 张明庆

    2001-01-01

    Results of the analysis suggest that during the recent 100 years there e xists a strong correlation between the El Nino/La Nina phenomenon and Beijing′s rainfall in summer(June—August),mean monthly maximum temperature (July) and mean monthly minimum temperature in winter (January).El Nino phenomenon appears a negative-correlation with the summer rainfall and the mean monthly minimum te mperature;whereas a positive correlation with the mean monthly maximum temperatu re in summer.La Nina phenomenon appears a positive correlation with the summer r ainfall and the mean monthly minimum temperature in winter;whereas a negative-c orrelation with the mean monthly maximum temperature in summer.%通过对近百年El Nino/La Nina事件与北京气候相关性研究发现,El Nino/ La Nina事件与北京夏季(6~8月)降水、平均最高气温(7月)和冬季(1月)平均最低气温之间 相互关系显著。El Nino事件与夏季降水、冬季平均最低气温呈负相关,与夏季平均最高气 温呈正相关,造成降水减少,气温年较差增大,大陆性增强的气候特点。La Nina事件与夏 季降水、冬季平均最低气温呈正相关,与夏季平均最高气温呈负相关,使降水增加,气温年 较差减小,大陆性减弱的气候特点。

  7. 中国近百年地面温度变化自然因子的因果链分析%The Causal Chain Analysis of Natural Factors for China Sur face Temperature Variation during the Recent 100 Years

    Institute of Scientific and Technical Information of China (English)

    朱玉祥; 赵亮

    2014-01-01

    采用格兰杰(Granger)因果检验法,从自然因素的角度,即从天文因子(太阳黑子数SSN)和地球运动因子(地极移动X方向和Y方向)的角度,对我国近百年地面温度(TC)的变化进行了归因分析。所得结果如下:滞后1~11年内, SSN都不是TC的Granger原因;对于TC和极移X方向,当滞后6年时信度最高,此时极移X方向是TC的Granger原因(87%信度)。研究结果可能暗示,极移X方向的变化可能会导致6年后中国地面气温的变化。%The attribution analysis of China surface temperature(TC) in the recent 100 years is done from the angle of the astronomical factor(sunspot number, SSN) and the earth movement factor(polar shift x direction and y direction ) by using Granger causality test. The results are as follows:(1) SSN is not the Granger cause of TC in all of 1 to 11 years lags;(2) when the lag is 6 years, conifdence is the highest, at this time polar shift x direction is the Granger cause of TC (87%conifdence);(3) when the lag is 12 years, TC is the Granger cause of the polar shift y direction, the conifdence is 86%. The research results of the paper suggest that the change of polar shift x direction possibly results in the change of TC, and the change of TC possibly inlfuences the change of the polar shift y direction.

  8. Estimates of Flow Duration, Mean Flow, and Peak-Discharge Frequency Values for Kansas Stream Locations

    Science.gov (United States)

    Perry, Charles A.; Wolock, David M.; Artman, Joshua C.

    2004-01-01

    Streamflow statistics of flow duration and peak-discharge frequency were estimated for 4,771 individual locations on streams listed on the 1999 Kansas Surface Water Register. These statistics included the flow-duration values of 90, 75, 50, 25, and 10 percent, as well as the mean flow value. Peak-discharge frequency values were estimated for the 2-, 5-, 10-, 25-, 50-, and 100-year floods. Least-squares multiple regression techniques were used, along with Tobit analyses, to develop equations for estimating flow-duration values of 90, 75, 50, 25, and 10 percent and the mean flow for uncontrolled flow stream locations. The contributing-drainage areas of 149 U.S. Geological Survey streamflow-gaging stations in Kansas and parts of surrounding States that had flow uncontrolled by Federal reservoirs and used in the regression analyses ranged from 2.06 to 12,004 square miles. Logarithmic transformations of climatic and basin data were performed to yield the best linear relation for developing equations to compute flow durations and mean flow. In the regression analyses, the significant climatic and basin characteristics, in order of importance, were contributing-drainage area, mean annual precipitation, mean basin permeability, and mean basin slope. The analyses yielded a model standard error of prediction range of 0.43 logarithmic units for the 90-percent duration analysis to 0.15 logarithmic units for the 10-percent duration analysis. The model standard error of prediction was 0.14 logarithmic units for the mean flow. Regression equations used to estimate peak-discharge frequency values were obtained from a previous report, and estimates for the 2-, 5-, 10-, 25-, 50-, and 100-year floods were determined for this report. The regression equations and an interpolation procedure were used to compute flow durations, mean flow, and estimates of peak-discharge frequency for locations along uncontrolled flow streams on the 1999 Kansas Surface Water Register. Flow durations, mean

  9. The PEAK experience in South Carolina

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    The PEAK Institute was developed to provide a linkage for formal (schoolteachers) and nonformal educators (extension agents) with agricultural scientists of Clemson University`s South Carolina Agricultural Experiment Station System. The goal of the Institute was to enable teams of educators and researchers to develop and provide PEAK science and math learning experiences related to relevant agricultural and environmental issues of local communities for both classroom and 4-H Club experiences. The Peak Institute was conducted through a twenty day residential Institute held in June for middle school and high school teachers who were teamed with an Extension agent from their community. These educators participated in hands-on, minds-on sessions conducted by agricultural researchers and Clemson University Cooperative Extension specialists. Participants were given the opportunity to see frontier science being conducted by scientists from a variety of agricultural laboratories.

  10. Conserved hypothetical BB0462 protein enhances the transcription activity of oppAV promoter

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Borrelia burgdorferi BB0462 ORF encodes an unknown functional protein with 110 amino acids.A BLAST search in protein databases and the secondary structure being predicted by the program JUFO showed that the conserved hypothetical BB0462 protein was similar to the members of the YbaB protein family in both amino acid composition and protein structure.The co-transformation of BB0462 ORF and oppA upstream regulation DNA into E.coli host cells and β-galactosidase activity assay demonstrated that the BB0462 protein enhanced the transcriptional activity of the oppAV promoter,but does not affect those of oppAⅠ,Ⅱ,Ⅲ and Ⅳ promoters.Analysis of DNA retardation and competitive repression also confirmed that the BB0462 protein bound to the 409 bp upstream regulation DNA fragment close to the initiation codon of the oppAV gene.All data in our study suggested that the BB0462 protein was involved in the transcriptional regulation of the oppAV gene

  11. "Hypothetical machines": the science fiction dreams of Cold War social science.

    Science.gov (United States)

    Lemov, Rebecca

    2010-06-01

    The introspectometer was a "hypothetical machine" Robert K. Merton introduced in the course of a 1956 how-to manual describing an actual research technique, the focused interview. This technique, in turn, formed the basis of wartime morale research and consumer behavior studies as well as perhaps the most ubiquitous social science tool, the focus group. This essay explores a new perspective on Cold War social science made possible by comparing two kinds of apparatuses: one real, the other imaginary. Even as Merton explored the nightmare potential of such machines, he suggested that the clear aim of social science was to build them or their functional equivalent: recording machines to access a person's experiential stream of reality, with the ability to turn this stream into real-time data. In this way, the introspectometer marks and symbolizes a broader entry during the Cold War of science-fiction-style aspirations into methodological prescriptions and procedural manuals. This essay considers the growth of the genre of methodological visions and revisions, painstakingly argued and absorbed, but punctuated by sci-fi aims to transform "the human" and build newly penetrating machines. It also considers the place of the nearly real-, and the artificial "near-substitute" as part of an experimental urge that animated these sciences.

  12. Hypothetical biotechnology companies: A role-playing student centered activity for undergraduate science students.

    Science.gov (United States)

    Chuck, Jo-Anne

    2011-01-01

    Science students leaving undergraduate programs are entering the biotechnology industry where they are presented with issues which require integration of science content. Students find this difficult as through-out their studies, most content is limited to a single subdiscipline (e.g., biochemistry, immunology). In addition, students need knowledge of the ethical, economic, and legal frame work in which the industry operates. This article presents an approach to deliver these outcomes in a collaborative and active learning modality which promotes deep learning. In the model, groups of final year undergraduate students form hypothetical biotechnology companies and identify real issues of interest to industry, make integrative team decisions, use professional level technology, and develop appropriate communication skills. The final successful teaching paradigm was based on self reflection, observation, and student feedback to ensure appropriate attainment of content, group work skills and increased confidence in professional decision-making. It is these outcomes which will facilitate life long learning skills, a major outcome applicable for all tertiary education.

  13. Testing the feasibility of a hypothetical whaling-conservation permit market in Norway.

    Science.gov (United States)

    Huang, Biao; Abbott, Joshua K; Fenichel, Eli P; Muneepeerakul, Rachata; Perrings, Charles; Gerber, Leah

    2017-02-24

    A "cap and trade" style system for managing whale harvests represents a potentially useful approach to resolve the current gridlock in international whale management. The establishment of whale permit markets, open to both whalers and conservationists, could reveal the strength of conservation demand. However, while much is known about demand for whale-based products there is uncertainty about demand for conservation and the willingness of conservation interests to engage in the market. This makes it difficult to predict the outcome of a hypothetical whale permit market. As a thought experiment, we develop a bioeconomic model to evaluate the influence of economic uncertainty about demand for whale conservation or harvest. We use simulations over a wide range of parameterizations of whaling and conservation demands to examine the potential ecological consequences of the establishment of a whale permit market in Norwegian waters under bounded (but substantial) economic uncertainty. We find that while a whale conservation market has the potential to yield a wide range of conservation and harvest outcomes, the most likely outcomes are those in which conservationists buy all whale permits. This article is protected by copyright. All rights reserved.

  14. Features of Hypothetical Plasma Phase Transition in Interiors of Saturn and Jupiter

    CERN Document Server

    Ukrainets, Artem

    2013-01-01

    Anomalous features for hypothetical Plasma Phase Transitions (PPT), which is expected to occur in mixed hydrogen-helium plasma in interior of Jupiter and Saturn, are under discussion. The characteristics of the Coulomb and density corrections (the so-called non-ideality corrections) are reconstructed for hydrogen-helium plasma in the vicinity of phase coexistence boundary of this PPT in version of Saumon and Chabrier, using tabular data for hydrogen-helium EOS of Saumon, Chabrier and VanHorn and some general thermodynamic relations. Two previously unknown characteristics of the studied PPT have been estimated based on these results: (i) -- the jump of the electrostatic potential across the phase boundary of PPT (Galvani potential), and (ii) -- the scale of non-congruency for this PPT (the differences in chemical composition of the coexisting hydrogen-helium phases), which could be expected in H2/He mixture at typical parameters of plasma in interior of Jupiter and Saturn. While the first effect -- the potenti...

  15. Identification of functional candidates amongst hypothetical proteins of Treponema pallidum ssp. pallidum.

    Science.gov (United States)

    Naqvi, Ahmad Abu Turab; Shahbaaz, Mohd; Ahmad, Faizan; Hassan, Md Imtaiyaz

    2015-01-01

    Syphilis is a globally occurring venereal disease, and its infection is propagated through sexual contact. The causative agent of syphilis, Treponema pallidum ssp. pallidum, a Gram-negative sphirochaete, is an obligate human parasite. Genome of T. pallidum ssp. pallidum SS14 strain (RefSeq NC_010741.1) encodes 1,027 proteins, of which 444 proteins are known as hypothetical proteins (HPs), i.e., proteins of unknown functions. Here, we performed functional annotation of HPs of T. pallidum ssp. pallidum using various database, domain architecture predictors, protein function annotators and clustering tools. We have analyzed the sequences of 444 HPs of T. pallidum ssp. pallidum and subsequently predicted the function of 207 HPs with a high level of confidence. However, functions of 237 HPs are predicted with less accuracy. We found various enzymes, transporters, binding proteins in the annotated group of HPs that may be possible molecular targets, facilitating for the survival of pathogen. Our comprehensive analysis helps to understand the mechanism of pathogenesis to provide many novel potential therapeutic interventions.

  16. Economic impacts of a hypothetical H1N1 pandemic : a cross-sectional analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Braeton J.; Shaneyfelt, Calvin R.

    2010-06-01

    A NISAC study on the economic effects of a hypothetical H1N1 pandemic was done in order to assess the differential impacts at the state and industry levels given changes in absenteeism, mortality, and consumer spending rates. Part of the analysis was to determine if there were any direct relationships between pandemic impacts and gross domestic product (GDP) losses. Multiple regression analysis was used because it shows very clearly which predictors are significant in their impact on GDP. GDP impact data taken from the REMI PI+ (Regional Economic Models, Inc., Policy Insight +) model was used to serve as the response variable. NISAC economists selected the average absenteeism rate, mortality rate, and consumer spending categories as the predictor variables. Two outliers were found in the data: Nevada and Washington, DC. The analysis was done twice, with the outliers removed for the second analysis. The second set of regressions yielded a cleaner model, but for the purposes of this study, the analysts deemed it not as useful because particular interest was placed on determining the differential impacts to states. Hospitals and accommodation were found to be the most important predictors of percentage change in GDP among the consumer spending variables.

  17. Hydrologic effects of hypothetical earthquake-caused floods below Jackson Lake, northwestern Wyoming

    Science.gov (United States)

    Glass, W.R.; Keefer, T.N.; Rankl, J.G.

    1976-01-01

    Jackson Lake, located in Grand Teton National Park, Wyoming, is in an area of seismic instability. There is a possibility of flooding in the Snake River downstream from Jackson Lake Dam in the event of a severe earthquake. Hypothetical floods were routed 38 miles (61 kilometers) downstream from the dam for three cases: (1) Instantaneous destruction of the dam outlet structure, (2) instantaneous destruction of the entire dam, and (3) for waves overtopping the dam without failure of the dam. In each case, a full reservoir was assumed. Hydrographs for outflow from the reservoir for the two cases of dam failure were developed utilizing an accelerated discharge due to the travel of a negative wave through the reservoir, and Muskingum storage routing. For the case of waves overtopping the dam, a 10-foot (3-meter) wave was assumed to be propagated from the upstream end of the reservori. A multiple-linearization technique was used to route the flow through the reach. The model was calibrated from U.S. Geological Survey streamflow records. Most extensive flooding and largest water velocities would occur if the entire dam were destroyed; floods for the other two cases were smaller. An inundation map was prepared from channel conveyance curves and profiles of the water surface. (Woodard-USGS)

  18. Radioactive particulate release associated with the DOT specification 6M container under hypothetical accident conditions

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, J.M.; Raney, P.J.

    1986-02-01

    A testing program was conducted to determine the leakage of depleted uranium dioxide powder (DUO) from the inner containment components of the US Department of Transportation's (DOT) specification 6M container under hypothetical accident conditions. Depleted uranium dioxide was selected as a surrogate for plutonium oxide because of the similarities in the powder characteristics, density and particle size, and because of the special handling and special facilities required for plutonium oxide. The DUO was packaged inside food pack cans in three different configurations inside the 2R vessel of the 6M container. The amount of DUO powder leakage ranged from none detectable (<2 x 10/sup -7/ g) to a high of 1 x 10/sup -3/ g. The combination of gravity, vibration and pressure produced the highest leakage of DUO. Containers that had hermetic seals (leak rates <6 x 10/sup -4/ atm cc/min) did not leak any detectable amount (<2 x 10/sup -7/ g) of DUO under the test conditions. Impact forces had no effect on the leakage of particles with the packaging configurations used. 23 refs., 24 figs., 3 tabs.

  19. Summary of four release consequence analyses for hypothetical nuclear waste repositories in salt and granite

    Energy Technology Data Exchange (ETDEWEB)

    Cole, C.R.; Bond, F.W.

    1980-12-01

    Release consequence methology developed under the Assessment of Effectiveness of Geologic Isolation Systems (AEGIS) program has now been applied to four hypothetical repository sites. This paper summarizes the results of these four studies in order to demonstrate that the far-field methodology developed under the AEGIS program offers a practical approach to the post-closure safety assessment of nuclear waste repositories sited in deep continental geologic formations. The four studies are briefly described and compared according to the following general categories: physical description of the repository (size, inventory, emplacement depth); geologic and hydrologic description of the site and the conceptual hydrologic model for the site; description of release scenario; hydrologic model implementation and results; engineered barriers and leach rate modeling; transport model implementation and results; and dose model implementation and results. These studies indicate the following: numerical modeling is a practical approach to post-closure safety assessment analysis for nuclear waste repositories; near-field modeling capability needs improvement to permit assessment of the consequences of human intrusion and pumping well scenarios; engineered barrier systems can be useful in mitigating consequences for postulated release scenarios that short-circuit the geohydrologic system; geohydrologic systems separating a repository from the natural biosphere discharge sites act to mitigate the consequences of postulated breaches in containment; and engineered barriers of types other than the containment or absorptive type may be useful.

  20. Modelling wet deposition in simulations of volcanic ash dispersion from hypothetical eruptions of Merapi, Indonesia

    Science.gov (United States)

    Dare, Richard A.; Potts, Rodney J.; Wain, Alan G.

    2016-10-01

    The statistical impact of including the process of wet deposition in dispersion model predictions of the movement of volcanic ash is assessed. Based on hypothetical eruptions of Merapi, Indonesia, sets of dispersion model simulations were generated, each containing four simulations per day over a period of three years, to provide results based on a wide range of atmospheric conditions. While on average dry sedimentation removes approximately 10% of the volcanic ash from the atmosphere during the first 24 h, wet deposition removes an additional 30% during seasons with highest rainfall (December and January) but only an additional 1% during August and September. The majority of the wet removal is due to in-cloud rather than below-cloud collection of volcanic ash particles. The largest uncertainties in the amount of volcanic ash removed by the process of wet deposition result from the choice of user-defined parameters used to compute the scavenging coefficient, and from the definition of the cloud top height. Errors in the precipitation field provided by the numerical weather prediction model utilised here have relatively less impact.

  1. Sequence Analysis of Hypothetical Proteins from 26695 to Identify Potential Virulence Factors

    Directory of Open Access Journals (Sweden)

    Ahmad Abu Turab Naqvi

    2016-09-01

    Full Text Available Helicobacter pylori is a Gram-negative bacteria that is responsible for gastritis in human. Its spiral flagellated body helps in locomotion and colonization in the host environment. It is capable of living in the highly acidic environment of the stomach with the help of acid adaptive genes. The genome of H. pylori 26695 strain contains 1,555 coding genes that encode 1,445 proteins. Out of these, 340 proteins are characterized as hypothetical proteins (HP. This study involves extensive analysis of the HPs using an established pipeline which comprises various bioinformatics tools and databases to find out probable functions of the HPs and identification of virulence factors. After extensive analysis of all the 340 HPs, we found that 104 HPs are showing characteristic similarities with the proteins with known functions. Thus, on the basis of such similarities, we assigned probable functions to 104 HPs with high confidence and precision. All the predicted HPs contain representative members of diverse functional classes of proteins such as enzymes, transporters, binding proteins, regulatory proteins, proteins involved in cellular processes and other proteins with miscellaneous functions. Therefore, we classified 104 HPs into aforementioned functional groups. During the virulence factors analysis of the HPs, we found 11 HPs are showing significant virulence. The identification of virulence proteins with the help their predicted functions may pave the way for drug target estimation and development of effective drug to counter the activity of that protein.

  2. Process design and economic analysis of a hypothetical bioethanol production plant using carob pod as feedstock.

    Science.gov (United States)

    Sánchez-Segado, S; Lozano, L J; de Los Ríos, A P; Hernández-Fernández, F J; Godínez, C; Juan, D

    2012-01-01

    A process for the production of ethanol from carob (Ceratonia siliqua) pods was designed and an economic analysis was carried out for a hypothetical plant. The plant was assumed to perform an aqueous extraction of sugars from the pods followed by fermentation and distillation to produce ethanol. The total fixed capital investment for a base case process with a capacity to transform 68,000 t/year carob pod was calculated as 39.61 millon euros (€) with a minimum bioethanol production cost of 0.51 €/L and an internal rate of return of 7%. The plant was found to be profitable at carob pod prices lower than 0.188 €/kg. An increase in the transformation capacity of the plant from 33,880 to 135,450 t/year was calculated to result in an increase in the internal rate of return from 5.50% to 13.61%. The obtained results show that carob pod is a promising alternative source for bioethanol production.

  3. The hypothetical ancestral animal. the Urmetazoa: telomerase activity in sponges (Porifera

    Directory of Open Access Journals (Sweden)

    ISABEL M. MÜLLER

    2003-05-01

    Full Text Available Sponges (Porifera represent the lowest metazoan phylum, characterized by a pronounced plasticity in the determination of cell lineages, and they are the closest related taxon to the hypothetical ancestral animal, the Urmetazoa, from which the metazoan lineages diverged. In a first approach to elucidate the molecular mechanisms controlling the switch from the cell lineage with a putative indefinite growth capacity to senescent, somatic cells, the activity of the telomerase as an indicator for immortality has been determined. The studies were performed with the marine demosponges Suberites domuncula and Geodia cydonium, in vivo with tissue but also in vitro using the primmorph system. Primmorphs are formed from dissociated cells which have retained their proliferation potency. It was found that the activity of telomerase in tissue of both sponges is high. Based on this and additional findings it is assumed that the separation of the senescent sponge cell lineage from the immortal germ-/somatic cell lineage is triggered by the loss of contact to cell adhesion factors. First evidence is included which suggests that the final progress of the senescent, telomerase-negative cells to cell death is caused by apoptosis.

  4. The labelling and reporting of euthanasia by Belgian physicians: a study of hypothetical cases.

    Science.gov (United States)

    Smets, Tinne; Cohen, Joachim; Bilsen, Johan; Van Wesemael, Yanna; Rurup, Mette L; Deliens, Luc

    2012-02-01

    Belgium legalized euthanasia in 2002. Physicians must report each euthanasia case to the Federal Control and Evaluation Committee. This study examines which end-of-life decisions (ELDs) Belgian physicians label 'euthanasia', which ELDs they think should be reported and the physician characteristics associated with correct labelling of euthanasia cases, the awareness that they should be reported and the reporting of them. Five hypothetical cases of ELDs: intensified pain alleviation, palliative/terminal sedation, euthanasia with neuromuscular relaxants, euthanasia with morphine and life-ending without patient request were presented in a cross-sectional survey of 914 physicians in Belgium in 2009. About 19% of physicians did not label a euthanasia case with neuromuscular relaxants 'euthanasia', 27% did not know that it should be reported. Most physicians labelled a euthanasia case with morphine 'intensification of pain and symptom treatment' (39%) or 'palliative/terminal sedation' (37%); 21% of physicians labelled this case 'euthanasia'. Cases describing other ELDs were sometimes also labelled 'euthanasia'. Factors associated with a higher likelihood of labelling a euthanasia case correctly were: living in Flanders, being informed about the euthanasia law and having a positive attitude towards societal control over euthanasia. Whether a physician correctly labelled the euthanasia cases strongly determined their reporting knowledge and intentions. There is no consensus among physicians about the labelling of euthanasia and other ELDs, and about which cases must be reported. Mislabelling of ELDs could impede societal control over euthanasia. The provision of better information to physicians appears to be necessary.

  5. Sequence Analysis of Hypothetical Proteins from Helicobacter pylori 26695 to Identify Potential Virulence Factors

    Science.gov (United States)

    Naqvi, Ahmad Abu Turab; Anjum, Farah; Khan, Faez Iqbal; Islam, Asimul; Ahmad, Faizan

    2016-01-01

    Helicobacter pylori is a Gram-negative bacteria that is responsible for gastritis in human. Its spiral flagellated body helps in locomotion and colonization in the host environment. It is capable of living in the highly acidic environment of the stomach with the help of acid adaptive genes. The genome of H. pylori 26695 strain contains 1,555 coding genes that encode 1,445 proteins. Out of these, 340 proteins are characterized as hypothetical proteins (HP). This study involves extensive analysis of the HPs using an established pipeline which comprises various bioinformatics tools and databases to find out probable functions of the HPs and identification of virulence factors. After extensive analysis of all the 340 HPs, we found that 104 HPs are showing characteristic similarities with the proteins with known functions. Thus, on the basis of such similarities, we assigned probable functions to 104 HPs with high confidence and precision. All the predicted HPs contain representative members of diverse functional classes of proteins such as enzymes, transporters, binding proteins, regulatory proteins, proteins involved in cellular processes and other proteins with miscellaneous functions. Therefore, we classified 104 HPs into aforementioned functional groups. During the virulence factors analysis of the HPs, we found 11 HPs are showing significant virulence. The identification of virulence proteins with the help their predicted functions may pave the way for drug target estimation and development of effective drug to counter the activity of that protein. PMID:27729842

  6. Bioinformatics and structural characterization of a hypothetical protein from Streptococcus mutans: implication of antibiotic resistance.

    Directory of Open Access Journals (Sweden)

    Jie Nan

    Full Text Available As an oral bacterial pathogen, Streptococcus mutans has been known as the aetiologic agent of human dental caries. Among a total of 1960 identified proteins within the genome of this organism, there are about 500 without any known functions. One of these proteins, SMU.440, has very few homologs in the current protein databases and it does not fall into any protein functional families. Phylogenetic studies showed that SMU.440 is related to a particular ecological niche and conserved specifically in some oral pathogens, due to lateral gene transfer. The co-occurrence of a MarR protein within the same operon among these oral pathogens suggests that SMU.440 may be associated with antibiotic resistance. The structure determination of SMU.440 revealed that it shares the same fold and a similar pocket as polyketide cyclases, which indicated that it is very likely to bind some polyketide-like molecules. From the interlinking structural and bioinformatics studies, we have concluded that SMU.440 could be involved in polyketide-like antibiotic resistance, providing a better understanding of this hypothetical protein. Besides, the combination of multiple methods in this study can be used as a general approach for functional studies of a protein with unknown function.

  7. Public acceptance of a hypothetical Ebola virus vaccine in Aceh, Indonesia: A hospital-based survey

    Directory of Open Access Journals (Sweden)

    Harapan Harapan

    2017-04-01

    Full Text Available Objective: To determine the acceptance towards a hypothetical Ebola virus vaccine (EVV and associated factors in a non-affected country, Indonesia. Methods: A hospital-based, cross-sectional study was conducted in four regencies of Aceh, Indonesia. A set of pre-tested questionnaires was used to obtain information on acceptance towards EVV and a range of explanatory variables. Associations between EVV acceptance and explanatory variables were tested using multi-steps logistic regression analysis and the Spearman's rank correlation. Results: Participants who had knowledge on Ebola virus disease (EVD were 45.3% (192/424 and none of the participants achieved 80% correct answers on the knowledge regarding to EVD. About 73% of participants expressed their willingness to receive the EVV. Education attainment, occupation, monthly income, have heard regarding to EVD previously, socioeconomic level, attitude towards vaccination practice and knowledge regarding to EVD were associated significantly with acceptance towards EVV in univariate analysis (P < 0.05. In the final multivariate model, socio-economic level, attitude towards vaccination practice and knowledge regarding to EVD were the independent explanatory variables for EVV acceptance. Conclusions: The knowledge of EVD was low, but this minimally affected the acceptance towards EVV. However, to facilitate optimal uptake of EVV, dissemination of vaccine-related information prior to its introduction is required.

  8. An Application of Graphical Approach to Construct Multiple Testing Procedure in a Hypothetical Phase III Design

    Directory of Open Access Journals (Sweden)

    Naitee eTing

    2014-01-01

    Full Text Available Many multiple testing procedures (MTP have been developed in recent years. Among these new procedures, the graphical approach is flexible and easy to communicate with non-statisticians. A hypothetical Phase III clinical trial design is introduced in this manuscript to demonstrate how graphical approach can be applied in clinical product development. In this design, an active comparator is used. It is thought that this test drug under development could potentially be superior to this comparator. For comparison of efficacy, the primary endpoint is well established and widely accepted by regulatory agencies. However, an important secondary endpoint based on Phase II findings looks very promising. The target dose may have a good opportunity to deliver superiority to the comparator. Furthermore, a lower dose is included in case the target dose may demonstrate potential safety concerns. This Phase III study is designed as a non-inferiority trial with two doses, and two endpoints. This manuscript will illustrate how graphical approach is applied to this design in handling multiple testing issues.

  9. Some Phenomenological Aspects of the Peak Experience

    Science.gov (United States)

    Rosenblatt, Howard S.; Bartlett, Iris

    1976-01-01

    This article relates the psychological dynamics of "peak experiences" to two concepts, intentionality and paradoxical intention, within the philosophical orientation of phenomenology. A review of early philosophical theories of self (Kant and Hume) is presented and compared with the experiential emphasis found in the phenomenology of Husserl.…

  10. Some Phenomenological Aspects of the Peak Experience

    Science.gov (United States)

    Rosenblatt, Howard S.; Bartlett, Iris

    1976-01-01

    This article relates the psychological dynamics of "peak experiences" to two concepts, intentionality and paradoxical intention, within the philosophical orientation of phenomenology. A review of early philosophical theories of self (Kant and Hume) is presented and compared with the experiential emphasis found in the phenomenology of Husserl.…

  11. Real estate price peaks: a comparative overview

    CERN Document Server

    Röhner, B M

    2006-01-01

    First, we emphasize that the real estate price peaks which are currently under way in many industrialized countries (one important exception is Japan) share many of the characteristics of previous historical price peaks. In particular, we show that: (i) In the present episode real price increases are, at least for now, of the same order of magnitude as in previous episodes, typically of the order of 80 percent to 100 percent. (ii) Historically, price peaks turned out to be symmetrical with respect to the peak; soft landing, i.e. an upgoing phase followed by a plateau, has rarely (if ever) been observed. (iii) The inflated demand is mainly boosted by investors and high-income buyers. (iv) In the present as well as in previous episodes, the main engines in the upgoing phase have been the hot markets which developed in major cities such as London, Los Angeles, New York, Paris, San Francisco or Sydney. In our conclusion, we propose a prediction for real estate prices in the West of the United States over the peri...

  12. Environmental sustainability comparison of a hypothetical pneumatic waste collection system and a door-to-door system.

    Science.gov (United States)

    Punkkinen, Henna; Merta, Elina; Teerioja, Nea; Moliis, Katja; Kuvaja, Eveliina

    2012-10-01

    Waste collection is one of the life cycle phases that influence the environmental sustainability of waste management. Pneumatic waste collection systems represent a new way of arranging waste collection in densely populated urban areas. However, limited information is available on the environmental impacts of this system. In this study, we compare the environmental sustainability of conventional door-to-door waste collection with its hypothetical pneumatic alternative. Furthermore, we analyse whether the size of the hypothetical pneumatic system, or the number of waste fractions included, have an impact on the results. Environmental loads are calculated for a hypothetical pneumatic waste collection system modelled on an existing dense urban area in Helsinki, Finland, and the results are compared to those of the prevailing, container-based, door-to-door waste collection system. The evaluation method used is the life-cycle inventory (LCI). In this study, we report the atmospheric emissions of greenhouse gases (GHG), SO(2) and NO(x). The results indicate that replacing the prevailing system with stationary pneumatic waste collection in an existing urban infrastructure would increase total air emissions. Locally, in the waste collection area, emissions would nonetheless diminish, as collection traffic decreases. While the electricity consumption of the hypothetical pneumatic system and the origin of electricity have a significant bearing on the results, emissions due to manufacturing the system's components prove decisive. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. Peak Discharge, Flood Profile, Flood Inundation, and Debris Movement Accompanying the Failure of the Upper Reservoir at the Taum Sauk Pump Storage Facility near Lesterville, Missouri

    Science.gov (United States)

    Rydlund, Jr., Paul H.

    2006-01-01

    The Taum Sauk pump-storage hydroelectric power plant located in Reynolds County, Missouri, uses turbines that operate as pumps and hydraulic head generated by discharging water from an upper to a lower reservoir to produce electricity. A 55-acre upper reservoir with a 1.5- billion gallon capacity was built on top of Proffit Mountain, approximately 760 feet above the floodplain of the East Fork Black River. At approximately 5:16 am on December 14, 2005, a 680-foot wide section of the upper reservoir embankment failed suddenly, sending water rushing down the western side of Proffit Mountain and emptying into the floodplain of East Fork Black River. Flood waters from the upper reservoir flowed downstream through Johnson's Shut-Ins State Park and into the lower reservoir of the East Fork Black River. Floods such as this present unique challenges and opportunities to analyze and document peak-flow characteristics, flood profiles, inundation extents, and debris movement. On December 16, 2005, Light Detection and Ranging (LiDAR) data were collected and used to support hydraulic analyses, forensic failure analyses, damage extent, and mitigation of future disasters. To evaluate the impact of sedimentation in the lower reservoir, a bathymetric survey conducted on December 22 and 23, 2005, was compared to a previous bathymetric survey conducted in April, 2005. Survey results indicated the maximum reservoir capacity difference of 147 acre-feet existed at a pool elevation of 730 feet. Peak discharge estimates of 289,000 cubic feet per second along Proffit Mountain and 95,000 cubic feet per second along the East Fork Black River were determined through indirect measurement techniques. The magnitude of the embankment failure flood along the East Fork Black River was approximately 4 times greater than the 100-year flood frequency estimate of 21,900 cubic feet per second, and approximately 3 times greater than the 500-year flood frequency estimate of 30,500 cubic feet per second

  14. Spanish Peaks, Sangre de Cristo Range, Colorado

    Science.gov (United States)

    2002-01-01

    The Spanish Peaks, on the eastern flank of the Sangre de Cristo range, abruptly rise 7,000 feet above the western Great Plains. Settlers, treasure hunters, trappers, gold and silver miners have long sighted on these prominent landmarks along the Taos branch of the Santa Fe trail. Well before the westward migration, the mountains figured in the legends and history of the Ute, Apache, Comanche, and earlier tribes. 'Las Cumbres Espanolas' are also mentioned in chronicles of exploration by Spaniards including Ulibarri in 1706 and later by de Anza, who eventually founded San Francisco (California). This exceptional view (STS108-720-32), captured by the crew of Space Shuttle mission STS108, portrays the Spanish Peaks in the context of the southern Rocky Mountains. Uplift of the Sangre de Cristo began about 75 million years ago and produced the long north-trending ridges of faulted and folded rock to the west of the paired peaks. After uplift had ceased (26 to 22 million years ago), the large masses of igneous rock (granite, granodiorite, syenodiorite) that form the Peaks were emplaced (Penn, 1995-2001). East and West Spanish Peaks are 'stocks'-bodies of molten rock that intruded sedimentary layers, cooled and solidified, and were later exposed by erosion. East Peak (E), at 12,708 ft is almost circular and is about 5 1/2 miles long by 3 miles wide, while West Peak (W), at 13,623 ft is roughly 2 3/4 miles long by 1 3/4 miles wide. Great dikes-long stone walls-radiate outward from the mountains like spokes of a wheel, a prominent one forms a broad arc northeast of East Spanish Peak. As the molten rock rose, it forced its way into vertical cracks and joints in the sedimentary strata; the less resistant material was then eroded away, leaving walls of hard rock from 1 foot to 100 feet wide, up to 100 feet high, and as long as 14 miles. Dikes trending almost east-west are also common in the region. For more information visit: Sangres.com: The Spanish Peaks (accessed January 16

  15. Ammonia synthesis catalyst 100 years:Practice, enlightenment and challenge%氨合成催化剂100年:实践、启迪和挑战

    Institute of Scientific and Technical Information of China (English)

    刘化章

    2014-01-01

    Haber-Bosch发明的氨合成催化剂创立已经100周年。介绍了氨合成催化剂在理论和实践方面的发展、成就及其启迪,展望了氨合成催化剂的未来和面临的新挑战。催化合成氨技术在20世纪化学工业的发展中起着核心的作用。一个世纪以来,氨合成催化剂经历了Fe3O4基熔铁催化剂、Fe1-xO基熔铁催化剂、Ru基催化剂等发展阶段,以及钴钼双金属氮化物催化剂的发现。实践表明,氨合成催化剂是多相催化领域中许多基础研究的起点和试金石,没有别的反应象氨合成反应一样,能够把理论、模型催化剂和实验连接起来。催化合成氨反应仍然是多相催化理论研究的一个理想的模型体系。理解该反应机理并转换成完美技术成为催化研究领域发展的基本标准。这个永不结束的故事仍然没有结束。除了关于反应的基本步骤、真实结构、亚氮化物这些问题之外,催化合成氨在理论上一个新的挑战是关于在室温和常压下氨合成的预测,包括电催化合成氨、光催化合成氨和化学模拟生物固氮以及包括氮分子在内的催化化学研究中几种最稳定的小分子的活化方法等。%Ammonia synthesis catalyst found by Haber-Bosch achieves its history of 100 years. The current understanding and enlightenment from foundation and development of ammonia synthesis catalyst are reviewed, and its future and facing new challenge remained today are expected. Catalytic ammo-nia synthesis technology has played a central role in the development of the chemical industry dur-ing the 20th century. During 100 years, ammonia synthesis catalyst has come through diversified seedtime such as Fe3O4-based iron catalysts, Fe1-xO-based iron catalysts, ruthenium-based catalysts, and discovery of a Co-Mo-N system. Often new techniques, methods, and theories of catalysis have initially been developed and applied in connection with studies of

  16. Effects of disclosing hypothetical genetic test results for salt sensitivity on salt restriction behavior

    Directory of Open Access Journals (Sweden)

    Takeshima T

    2013-05-01

    Full Text Available Taro Takeshima,1,2 Masanobu Okayama,1 Masanori Harada,3 Ryusuke Ae,4 Eiji Kajii1 1Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University, Tochigi, Japan; 2Department of Healthcare Epidemiology, Kyoto University Graduate School of Medicine and Public Health, Kyoto, Japan; 3Department for Support of Rural Medicine, Yamaguchi Grand Medical Center, Yamaguchi, Japan; 4Department of General Internal Medicine, Hamasaka Public Hospital, Mikata, Japan Background: A few studies have explored the effects of disclosure of genetic testing results on chronic disease predisposition. However, these effects remain unclear in cases of hypertension. Reducing salt intake is an important nonpharmacological intervention for hypertension. We investigated the effects of genetic testing for salt sensitivity on salt restriction behavior using hypothetical genetic testing results. Methods: We conducted a cross-sectional study using a self-completed questionnaire. We enrolled consecutive outpatients who visited primary care clinics and small hospitals between September and December 2009 in Japan. We recorded the patients’ baseline characteristics and data regarding their salt restriction behavior, defined as reducing salt intake before and after disclosure of hypothetical salt sensitivity genetic test results. Behavioral stage was assessed according to the five-stage transtheoretical model. After dividing subjects into salt restriction and no salt restriction groups, we compared their behavioral changes following positive and negative test results and analyzed the association between the respondents’ characteristics and their behavioral changes. Results: We analyzed 1562 participants with a mean age of 58 years. In the no salt restriction group, which included patients at the precontemplation, contemplation, and preparation stages, 58.7% stated that their behavioral stage progressed after a positive test result, although 29

  17. Historic Seismicity, Computed Peak Ground Accelerations, and Seismic Site Conditions for Northeast Mexico

    Science.gov (United States)

    Montalvo-Arriet, J. C.; Galván-Ramírez, I. N.; Ramos-Zuñiga, L. G.; Navarro de León, I.; Ramírez-Fernández, J. A.; Quintanilla-López, Y.; Cavazos-Tovar, N. P.

    2007-05-01

    In this study we present the historic seismicity, computed peak ground accelerations, and mapping of seismic site conditions for northeast Mexico. We start with a compilation of the regional seismicity in northeast Mexico (24- 31°N, 87-106°W) for the 1787-2006 period. Our study area lies within three morphotectonic provinces: Basin and Range and Rio Grande rift, Sierra Madre Oriental and Gulf Coastal Plain. Peak ground acceleration (PGA) maps were computed for three different scenarios: 1928 Parral, Chihuahua (MW = 6.5); 1931 Valentine, Texas (MW = 6.4); and a hypothetical earthquake located in central Coahuila (MW = 6.5). Ground acceleration values were computed using attenuation relations developed for central and eastern North America and the Basin and Range province. The hypothetical earthquake in central Coahuila is considered a critical scenario for the main cities of northeast Mexico. The damage associated with this hypothetical earthquake could be severe because the majority of the buildings were constructed without allowance for seismic accelerations. The expected PGA values in Monterrey, Saltillo and Monclova range from 30 to 70 cm/s2 (0.03 to 0.07g). This earthquake might also produce or trigger significant landslides and rock falls in the Sierra Madre Oriental, where several cities are located (e.g. suburbs of Monterrey). Additionally, the Vs30 distribution for the state of Nuevo Leon and the cities of Linares and Monterrey are presented. The Vs30 data was obtained using seismic refraction profiling correlated with borehole information. According to NEHRP soil classification, sites classes A, B and C are dominant. Sites with class D occupy minor areas in both cities. Due to the semi-arid conditions in northeast Mexico, we obtained the highest values of Vs30 in Quaternary deposits (alluvium) cemented by caliche. Similar values of Vs30 were obtained in Reno and Las Vegas, Nevada. This work constitutes the first attempt at understanding and

  18. RELAP5 analyses of two hypothetical flow reversal events for the advanced neutron source reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chen, N.C.J.; Wendel, M.W.; Yoder, G.L. Jr. [Oak Ridge National Lab., TN (United States)

    1995-09-01

    This paper presents RELAP5 results of two hypothetical, low flow transients analyzed as part of the Advanced Neutron Source Reactor safety program. The reactor design features four independent coolant loops (three active and one in standby), each containing a main curculation pump (with battery powered pony motor), heat exchanger, an accumulator, and a check valve. The first transient assumes one of these pumps fails, and additionally, that the check valve in that loop remains stuck in the open position. This accident is considered extremely unlikely. Flow reverses in this loop, reducing the core flow because much of the coolant is diverted from the intact loops back through the failed loop. The second transient examines a 102-mm-diam instantaneous pipe break near the core inlet (the worst break location). A break is assumed to occur 90 s after a total loss-of-offsite power. Core flow reversal occurs because accumulator injection overpowers the diminishing pump flow. Safety margins are evaluated against four thermal limits: T{sub wall}=T{sub sat}, incipient boiling, onset of significant void, and critical heat flux. For the first transient, the results show that these limits are not exceeded (at a 95% non-exceedance probability level) if the pony motor battery lasts 30 minutes (the present design value). For the second transient, the results show that the closest approach of the fuel surface temperature to the local saturation temperature during core flow reversal is about 39{degrees}C. Therefore the fuel remains cool during this transient. Although this work is done specifically for the ANSR geometry and operating conditions, the general conclusions may be applicable to other highly subcooled reactor systems.

  19. Phototaxic foraging of the archaepaddler, a hypothetical deep-sea species.

    Science.gov (United States)

    Bertin, R J; van de Grind, W A

    1998-01-01

    An autonomous agent (animat, hypothetical animal), called the (archae) paddler, is simulated in sufficient detail to regard its simulated aquatic locomotion (paddling) as physically possible. The paddler is supposed to be a model of an animal that might exist, although it is perfectly possible to view it as a model of a robot that might be built. The agent is assumed to navigate in a simulated deep-sea environment, where it forages for autoluminescent prey. It uses a biologically inspired phototaxic foraging strategy, while paddling in a layer just above the bottom. The advantage of this living space is that the navigation problem--and hence our model--is essentially two-dimensional. Moreover, the deep-sea environment is physically simple (and hence easy to simulate): no significant currents, constant temperature, completely dark. A foraging performance metric is developed that circumvents the necessity to solve the traveling salesman problem. A parametric simulation study then quantifies the influence of habitat factors, such as the density of prey, and body geometry (e.g., placement, direction and directional selectivity of the eyes) on foraging success. Adequate performance proves to require a specific body geometry adapted to the habitat characteristics. In general, performance degrades gracefully for modest changes of the geometric and habitat parameters, indicating that we work in a stable region of "design space." The parameters have to strike a compromise between, on the one hand, to "see" as many targets at the same time as possible. One important conclusion is that simple reflex-based navigation can be surprisingly efficient. Additionally, performance in a global task (foraging) depends strongly on local parameters such as visual direction tuning, position of the eyes and paddles, and so forth. Behavior and habitat "mold" the body, and the body geometry strongly influences performance. The resulting platform enables further testing of foraging strategies

  20. Neonatal nurses' response to a hypothetical premature birth situation: What if it was my baby?

    Science.gov (United States)

    Green, Janet; Darbyshire, Philip; Adams, Anne; Jackson, Debra

    2016-12-09

    Evolving technology and scientific advancement have increased the chances of survival of the extremely premature baby; however, such survival can be associated with some severe long-term morbidities. The research investigates the caregiving and ethical dilemmas faced by neonatal nurses when caring for extremely premature babies (defined as ≤24 weeks' gestation). This article explores the issues arising for neonatal nurses when they considered the philosophical question of 'what if it was me and my baby', or what they believed they would do in the hypothetical situation of going into premature labour and delivering an extremely premature baby. Data were collected via a questionnaire to Australian neonatal nurses and semi-structured interviews with 24 neonatal nurses in New South Wales, Australia. Relevant ethical approvals have been obtained by the researchers. A qualitative approach was used to analyse the data. The theme 'imagined futures' was generated which comprised three sub-themes: 'choice is important', 'not subjecting their own baby to treatment' and 'nurses and outcome predictions'. The results offer an important and unique understanding into the perceptions of nursing staff who care for extremely premature babies and their family, see them go home and witness their evolving outcomes. The results show that previous clinical and personal experiences led the nurses in the study to choose to have the belief that if in a similar situation, they would choose not to have their own baby resuscitated and subjected to the very treatment that they provide to other babies. The theme 'imagined futures' offers an overall understanding of how neonatal nurses imagine what the life of the extremely premature baby and his or her family will be like after discharge from neonatal intensive care. The nurses' past experience has led them to believe that they would not want this life for themselves and their baby, if they were to deliver at 24 weeks' gestation or less. © The

  1. Increasing membrane interactions of local anaesthetics as hypothetic mechanism for their cardiotoxicity enhanced by myocardial ischaemia.

    Science.gov (United States)

    Tsuchiya, Hironori; Mizogami, Maki; Shigemi, Kenji

    2012-11-01

    While myocardial ischaemia enhances the cardiotoxicity of local anaesthetics, the pharmacological background remains unclear. Cardiolipin (CL) localized in mitochondrial membranes is possibly the site of cardiotoxic action of local anaesthetics and peroxynitrite is produced by cardiac ischaemia and reperfusion. We verified the hypothetic mechanism that local anaesthetics may interact with CL-containing biomembranes to change the membrane biophysical property and their membrane interactions may be increased by peroxynitrite. Biomimetic membranes were prepared with different phospholipids and cholesterol of varying compositions. The membrane preparations were reacted with peroxynitrite of pathologically relevant concentrations and local anaesthetics (bupivacaine and lidocaine) of a cardiotoxic concentration separately or in combination. Changes in membrane fluidity were determined by measuring fluorescence polarization. Peroxynitrite decreased the fluidity of biomimetic membranes at 0.1-10 μM with the relative potency being CL>1-stearoyl-2-arachidonoylphosphatidylcholine>1,2-dipalmitoylphosphatidylcholine-constituting membranes, indicating the lipid peroxidation-induced membrane rigidification determined by the unsaturation degree of membrane lipids. When treated with 0.1-10 μM peroxynitrite, biomimetic membranes were more rigid with elevating the CL content from 0% to 30 mol%, suggesting that CL is a primary target of peroxynitrite. Bupivacaine and lidocaine fluidized at 200 μM biomimetic membranes containing 10 mol% CL and their effects were increased by pre-treating the membranes with 0.1 and 1 μM peroxynitrite. Cardiotoxic bupivacaine and lidocaine increasingly interact with CL-containing mitochondria model membranes which are relatively rigidified by peroxynitrite. Such an increasing membrane interaction may be, at least in part, responsible for the local anaesthetic cardiotoxicity enhanced by myocardial ischaemia.

  2. Role of gender norms and group identification on hypothetical and experimental pain tolerance.

    Science.gov (United States)

    Pool, Gregory J; Schwegler, Andria F; Theodore, Brian R; Fuchs, Perry N

    2007-05-01

    Previous research indicates that men typically tolerate more pain in experimental settings than women. One likely explanation for these group differences in pain tolerance is conformity to traditional, gender group social norms (i.e., the ideal man is masculine and tolerates more pain; the ideal woman is feminine and tolerates less pain). According to self-categorization theory, norms guide behavior to the degree that group members adopt the group identity. Therefore, high-identifying men are expected to conform to gender norms and tolerate more pain than high-identifying women who conform to different gender norms as a guide for their behavior. We conducted two studies to investigate whether gender group identification moderates individuals' conformity to pain tolerance and reporting norms. In the first study, participants indicated their gender identification and expected tolerance of a hypothetical painful stimulus. As anticipated, high-identifying men reported significantly greater pain tolerance than high-identifying women. No differences existed between low-identifying men and women. To determine if self-reported pain tolerance in a role-playing scenario corresponds to actual pain tolerance in an experimental setting, the second study examined pain tolerance to a noxious stimulus induced by electrical stimulation of the index finger. The experimental outcome revealed that high-identifying men tolerated more painful stimulation than high-identifying women. Further, high-identifying men tolerated more pain than low-identifying men. These results highlight the influence of social norms on behavior and suggest the need to further explore the role of norms in pain reporting behaviors.

  3. Soil carbon sequestration, carbon markets, and conservation agriculture practices: A hypothetical examination in Mozambique

    Directory of Open Access Journals (Sweden)

    Timoteo E. Simone

    2017-09-01

    Full Text Available Payments for Environmental Services (PES are relatively novel mechanisms whereby the adoption of sustainable management practices by a stakeholder is rewarded by incentives linked to external markets. Adoption of PES for conservation agricultural practices (CAPS by smallholder farmers may provide opportunities to increase household income or cover the technology costs of adoption if the carbon sequestration benefits of CAPS are quantifiable, adoption rates are accelerated and maintained, a mechanism exists whereby carbon sequestration services can be compensated, and carbon offset exchange markets are viable. This research suggests a methodology to examine a PES market for carbon offsets generated by the adoption of CAPS by farmers in Mozambique. Assuming a cumulative adoption of 60% over a 20-year period, revenue from PES market participation to CA adopters was two times higher than revenue earned when disadoption occurred midway through the simulation. Lower adoption targets are associated with higher per household returns when fertilizer rates typical to the region are increased. Establishing and maintaining a sustainable PES system in the study region would require significant investment in time and resources. The lack of on-the-ground institutions or local support for such a program would also challenge successful implementation. Finally, the programs where participant success depends on external markets, such as the hypothetical one suggested here, are subject to the ebb and flow of foreign demand for carbon offsets. Addressing these three broad constraints to a PES/CAPS program in the region would require grass-roots driven policy initiatives with buy-in at multiple social, economic, and political levels.

  4. Contribution of sponge genes to unravel the genome of the hypothetical ancestor of Metazoa (Urmetazoa).

    Science.gov (United States)

    Müller, W E; Schröder, H C; Skorokhod, A; Bünz, C; Müller, I M; Grebenjuk, V A

    2001-10-03

    Recently the term Urmetazoa, as the hypothetical metazoan ancestor, was introduced to highlight the finding that all metazoan phyla including the Porifera (sponges) are derived from one common ancestor. Sponges as the evolutionarily oldest, still extant phylum, are provided with a complex network of structural and functional molecules. Analyses of sponge genomes from Demospongiae (Suberites domuncula and Geodia cydonium), Calcarea (Sycon raphanus) and Hexactinellida (Aphrocallistes vastus) have contributed also to the reconstruction of the evolutionary position of Metazoa with respect to Fungi. Furthermore, these analyses have provided evidence that the characteristic evolutionary novelties of Metazoa, such as the extracellular matrix molecules, the cell surface receptors, the nervous signal transduction molecules as well as the immune molecule existing in Porifera, share high sequence and in some aspects also functional similarities to related polypeptides found in other metazoan phyla. During the transition to Metazoa new domains occurred; as one example, the formation of the death domain from the ankyrin is outlined. In parallel, domanial proteins have been formed, such as the receptor tyrosine kinases. The metazoan essentials have been defined by analyzing and comparing the sponge sequences with the related sequences from the metazoans Homo sapiens, Caenorhabditis elegans and Drosophila melanogaster, the fungus Saccharomyces cerevisiae and the plant Arabidopsis thaliana. The data revealed that those sponge molecules grouped to cell adhesion cell recognition proteins are predominantly found in Protostomia and Deuterostomia while they are missing in Fungi and Viridiplantae. Moreover, evidence is presented allowing the conclusion that the sponge molecules are more closely related to the corresponding molecules from H. sapiens than to those of C. elegans or D. melanogaster. Especially surprising was the finding that the Demospongiae are provided with elements of

  5. Plutonium Worlds. Fast Breeders, Systems Analysis and Computer Simulation in the Age of Hypotheticality

    Directory of Open Access Journals (Sweden)

    Sebastian Vehlken

    2014-09-01

    Full Text Available This article examines the media history of one of the hallmark civil nuclear energy programs in Western Germany – the development of Liquid Metal Fast Breeder Reactor (LMFBR technology. Promoted as a kind of perpetuum mobile of the Atomic Age, the "German Manhattan Project" not only imported big science thinking. In its context, nuclear technology was also put forth as an avantgarde of scientific inquiry, dealing with the most complex and critical technological endeavors. In the face of the risks of nuclear technology, German physicist Wolf Häfele thus announced a novel epistemology of "hypotheticality". In a context where traditional experimental engineering strategies became inappropiate, he called for the application of advanced media technologies: Computer Simulations (CS and Systems Analysis (SA generated computerized spaces for the production of knowledge. In the course of the German Fast Breeder program, such methods had a twofold impact. One the one hand, Häfele emphazised – as the "father of the German Fast Breeder" – the utilization of CS for the actual planning and construction of the novel reactor type. On the other, namely as the director of the department of Energy Systems at the International Institute for Applied Systems Analysis (IIASA, Häfele advised SA-based projections of energy consumption. These computerized scenarios provided the rationale for the conception of Fast Breeder programs as viable and necessary alternative energy sources in the first place. By focusing on the role of the involved CS techniques, the paper thus investigates the intertwined systems thinking of nuclear facilities’s planning and construction and the design of large-scale energy consumption and production scenarios in the 1970s and 1980s, as well as their conceptual afterlives in our contemporary era of computer simulation.

  6. Hypothetical influence of non-indexed Spanish journals on the impact factor of radiological journals

    Energy Technology Data Exchange (ETDEWEB)

    Miguel-Dasit, Alberto [MR Section, La Plana de Vila-Real Hospital, Castellon (Spain); Aleixandre, Rafael [Institute of History of Science and Documentation Lopez Pinero, University of Valencia-CSIC, Valencia (Spain); Valderrama, Juan C. [Institute of History of Science and Documentation Lopez Pinero, University of Valencia-CSIC, Valencia (Spain); Marti-Bonmati, Luis [Department of Radiology, MR Section, Dr. Peset University Hospital, Avenida Gaspar Aguilar 90, E-46017 Valencia (Spain)]. E-mail: marti_lui@gva.es; Sanfeliu, Pilar [Cardenal Herrera-CEU University, Alfara, Valencia (Spain)

    2005-06-01

    Objective: The aim of this study was to analyze the hypothetical changes in the 2001 impact factor of 52 radiological journals included in the Science Citation Index-Journal Citation Reports by also counting cites proceeding from 73 Spanish journals on different medical specialties. Also, to estimate the possible impact factor of the official Spanish radiology journal, Radiologia, not included in this database. Materials and methods: A modified 2001 impact factor of 52 radiological journals and Radiologia was obtained by adding the number of cites in 1999 and 2000 from the medical Spanish journals. Data were obtained by consulting the 2001 edition of the Journal Citation Reports in the 'Web of Science' database. Results: The 16,985 bibliographical references were analysed (232 of them to radiological journals). The journal with the largest increase in its 2001 impact factor (from 1.83 to 1.90) was Radiologic Clinics of North America. European Journal of Radiology was the European journal with the highest increase (from 1.084 to 1.110) in the difference between the 2001 modified and original impact factor. The modified 2001 impact factor of the 34 American journals was statistically higher (P = 0.016) than that of the 18 European journals (1.64 versus 0.93). Differences between the 2001 modified and original impact factor were slightly higher in the American journals (no statistically significant difference). The 2001 impact factor of Radiologia was 0.056. Discussion: Differences between the 2001 original and modified impact factor were small, but larger in the American journals. The 2001 impact factor of Radiologia was modest, although similar to other publications included in the Journal Citation Reports.

  7. Predicting VO2peak from Submaximal- and Peak Exercise Models: The HUNT 3 Fitness Study, Norway.

    Directory of Open Access Journals (Sweden)

    Henrik Loe

    Full Text Available Peak oxygen uptake (VO2peak is seldom assessed in health care settings although being inversely linked to cardiovascular risk and all-cause mortality. The aim of this study was to develop VO2peak prediction models for men and women based on directly measured VO2peak from a large healthy population.VO2peak prediction models based on submaximal- and peak performance treadmill work were derived from multiple regression analysis. 4637 healthy men and women aged 20-90 years were included. Data splitting was used to generate validation and cross-validation samples.The accuracy for the peak performance models were 10.5% (SEE = 4.63 mL⋅kg(-1⋅min(-1 and 11.5% (SEE = 4.11 mL⋅kg(-1⋅min(-1 for men and women, respectively, with 75% and 72% of the variance explained. For the submaximal performance models accuracy were 14.1% (SEE = 6.24 mL⋅kg(-1⋅min(-1 and 14.4% (SEE = 5.17 mL⋅kg(-1⋅min(-1 for men and women, respectively, with 55% and 56% of the variance explained. The validation and cross-validation samples displayed SEE and variance explained in agreement with the total sample. Cross-classification between measured and predicted VO2peak accurately classified 91% of the participants within the correct or nearest quintile of measured VO2peak.Judicious use of the exercise prediction models presented in this study offers valuable information in providing a fairly accurate assessment of VO2peak, which may be beneficial for risk stratification in health care settings.

  8. Effect of gear ratio on peak power and time to peak power in BMX cyclists.

    Science.gov (United States)

    Rylands, Lee P; Roberts, Simon J; Hurst, Howard T

    2017-03-01

    The aim of this study was to ascertain if gear ratio selection would have an effect on peak power and time to peak power production in elite Bicycle Motocross (BMX) cyclists. Eight male elite BMX riders volunteered for the study. Each rider performed three, 10-s maximal sprints on an Olympic standard indoor BMX track. The riders' bicycles were fitted with a portable SRM power meter. Each rider performed the three sprints using gear ratios of 41/16, 43/16 and 45/16 tooth. The results from the 41/16 and 45/16 gear ratios were compared to the current standard 43/16 gear ratio. Statistically, significant differences were found between the gear ratios for peak power (F(2,14) = 6.448; p = .010) and peak torque (F(2,14) = 4.777; p = .026), but no significant difference was found for time to peak power (F(2,14) = 0.200; p = .821). When comparing gear ratios, the results showed a 45/16 gear ratio elicited the highest peak power,1658 ± 221 W, compared to 1436 ± 129 W and 1380 ± 56 W, for the 43/16 and 41/16 ratios, respectively. The time to peak power showed a 41/16 tooth gear ratio attained peak power in -0.01 s and a 45/16 in 0.22 s compared to the 43/16. The findings of this study suggest that gear ratio choice has a significant effect on peak power production, though time to peak power output is not significantly affected. Therefore, selecting a higher gear ratio results in riders attaining higher power outputs without reducing their start time.

  9. The Doppler peaks from a generic defect

    CERN Document Server

    Magueijo, J

    1996-01-01

    We investigate which of the exotic Doppler peak features found for textures and cosmic strings are generic novelties pertaining to defects. We find that the ``out of phase'' texture signature is an accident. Generic defects, when they generate a secondary peak structure similar to inflation, apply to it an additive shift. It is not necessary for this shift to be ``out of phase''. We also show which factors are responsible for the absence of secondary oscillations found for cosmic strings. Within this general analysis we finally consider the conditions under which topological defects and inflation can be confused. It is argued that only \\Omega=1 inflation and a defect with a horizon size coherence length have a chance to be confused. Any other inflationary or defect model always differ distinctly. (To appear in the proceedings of the XXXIth Moriond meeting, ``Microwave Background Anisotropies'')

  10. Solar Cycle 24: is the peak coming?

    CERN Document Server

    Sello, Stefano

    2012-01-01

    Solar cycle activity forecasting, mainly its magnitude and timing, is an essential issue for numerous scientific and technological applications: in fact, during an active solar period, many strong eruptions occur on the Sun with increasing frequency, such as flares, coronal mass ejections, high velocity solar wind photons and particles, which can severely affect the Earth's ionosphere and the geomagnetic field, with impacts on the low atmosphere. Thus it is very important to develop reliable solar cycle prediction methods for the incoming solar activity. The current solar cycle 24 appeared unusual from many points of view: an unusually extended minimum period, and a global low activity compared to those of the previous three or four cycles. Currently, there are many different evidences that the peak in the northern hemisphere already occurred at 2011.6 but not yet in the southern hemisphere. In this brief note we update the peak prediction and its timing, based on the most recent observations.

  11. Peak oil, food systems, and public health.

    Science.gov (United States)

    Neff, Roni A; Parker, Cindy L; Kirschenmann, Frederick L; Tinch, Jennifer; Lawrence, Robert S

    2011-09-01

    Peak oil is the phenomenon whereby global oil supplies will peak, then decline, with extraction growing increasingly costly. Today's globalized industrial food system depends on oil for fueling farm machinery, producing pesticides, and transporting goods. Biofuels production links oil prices to food prices. We examined food system vulnerability to rising oil prices and the public health consequences. In the short term, high food prices harm food security and equity. Over time, high prices will force the entire food system to adapt. Strong preparation and advance investment may mitigate the extent of dislocation and hunger. Certain social and policy changes could smooth adaptation; public health has an essential role in promoting a proactive, smart, and equitable transition that increases resilience and enables adequate food for all.

  12. Excursion set peaks: the role of shear

    CERN Document Server

    Castorina, Emanuele; Hahn, Oliver; Sheth, Ravi K

    2016-01-01

    Recent analytical work on the modelling of dark halo abundances and clustering has demonstrated the advantages of combining the excursion set approach with peaks theory. We extend these ideas and introduce a model of excursion set peaks that incorporates the role of initial tidal effects or shear in determining the gravitational collapse of dark haloes. The model -- in which the critical density threshold for collapse depends on the tidal influences acting on protohaloes -- is well motivated from ellipsoidal collapse arguments and is also simple enough to be analytically tractable. We show that the predictions of this model are in very good agreement with measurements of the halo mass function and traditional scale dependent halo bias in N-body simulations across a wide range of masses and redshift. The presence of shear in the collapse threshold means that halo bias is naturally predicted to be nonlocal, and that protohalo densities at fixed mass are naturally predicted to have Lognormal-like distributions. ...

  13. Reducing Peak Power in Automated Weapon Laying

    Science.gov (United States)

    2016-02-01

    The values used are determined based on a number of factors including available power, maximum motor speed , maximum safe slewing speeds , peak...METHODS, ASSUMPTIONS, AND PROCEDURES Conventions and Variable Definitions Before describing the formulas to solve the aforementioned problems, it is...These two formulas are set equal to each other in equation 9 and then solved for t2 in equation 10. Note that the negative value of α2 results in a

  14. Hanford Site peak gust wind speeds

    Energy Technology Data Exchange (ETDEWEB)

    Ramsdell, J.V.

    1998-09-29

    Peak gust wind data collected at the Hanford Site since 1945 are analyzed to estimate maximum wind speeds for use in structural design. The results are compared with design wind speeds proposed for the Hanford Site. These comparisons indicate that design wind speeds contained in a January 1998 advisory changing DOE-STD-1020-94 are excessive for the Hanford Site and that the design wind speeds in effect prior to the changes are still appropriate for the Hanford Site.

  15. METing SUSY on the Z peak

    Energy Technology Data Exchange (ETDEWEB)

    Barenboim, G.; Bernabeu, J.; Vives, O. [Universitat de Valencia, Departament de Fisica Teorica, Burjassot (Spain); Universitat de Valencia-CSIC, Parc Cientific U.V., IFIC, Paterna (Spain); Mitsou, V.A.; Romero, E. [Universitat de Valencia-CSIC, Parc Cientific U.V., IFIC, Paterna (Spain)

    2016-02-15

    Recently the ATLAS experiment announced a 3 σ excess at the Z-peak consisting of 29 pairs of leptons together with two or more jets, E{sub T}{sup miss} > 225 GeV and HT > 600 GeV, to be compared with 10.6 ± 3.2 expected lepton pairs in the Standard Model. No excess outside the Z-peak was observed. By trying to explain this signal with SUSY we find that only relatively light gluinos, m{sub g} or similar 400 GeV decaying predominantly to Z-boson plus a light gravitino, such that nearly every gluino produces at least one Z-boson in its decay chain, could reproduce the excess. We construct an explicit general gauge mediation model able to reproduce the observed signal overcoming all the experimental limits. Needless to say, more sophisticated models could also reproduce the signal, however, any model would have to exhibit the following features: light gluinos, or heavy particles with a strong production cross section, producing at least one Z-boson in its decay chain. The implications of our findings for the Run II at LHC with the scaling on the Z peak, as well as for the direct search of gluinos and other SUSY particles, are pointed out. (orig.)

  16. Will peak oil accelerate carbon dioxide emissions?

    Science.gov (United States)

    Caldeira, K.; Davis, S. J.; Cao, L.

    2008-12-01

    The relative scarcity of oil suggests that oil production is peaking and will decline thereafter. Some have suggested that this represents an opportunity to reduce carbon dioxide emissions. However, in the absence of constraints on carbon dioxide emission, "peak oil" may drive a shift towards increased reliance on coal as a primary energy source. Because coal per unit energy, in the absence of carbon capture and disposal, releases more carbon dioxide to the atmosphere than oil, "peak oil" may lead to an acceleration of carbon dioxide emissions. We will never run out of oil. As oil becomes increasingly scarce, prices will rise and therefore consumption will diminish. As prices rise, other primary energy sources will become increasingly competitive with oil. The developed world uses oil primarily as a source of transportation fuels. The developing world uses oil primarily for heat and power, but the trend is towards increasing reliance on oil for transportation. Liquid fuels, including petroleum derivatives such as gasoline and diesel fuel, are attractive as transportation fuels because of their relative abundance of energy per unit mass and volume. Such considerations are especially important for the air transport industry. Today, there is little that can compete with petroleum-derived transportation fuels. Future CO2 emissions from the transportation sector largely depend on what replaces oil as a source of fuel. Some have suggested that biomass-derived ethanol, hydrogen, or electricity could play this role. Each of these potential substitutes has its own drawbacks (e.g., low power density per unit area in the case of biomass, low power density per unit volume in the case of hydrogen, and low power density per unit mass in the case of battery storage). Thus, it is entirely likely that liquefaction of coal could become the primary means by which transportation fuels are produced. Since the burning of coal produces more CO2 per unit energy than does the burning of

  17. Effect of Rainfall on Traffic Stream Characteristics during Peak and Non-Peak Periods

    Directory of Open Access Journals (Sweden)

    Hashim Mohammed Alhassan

    2012-01-01

    Full Text Available This paper examined the effect of rainfall on traffic stream behaviour during  peak and non-peak periods on a basic highway section. Data on this section which is located on the J5 was collected for four months during which 99 rainfall events occurred. The traffic consisted of 75.80% cars, 10.23% motorcycles, 3.51% trucks and 10.46%  of other vehicles. Traffic was observed for both rain and no-rain conditions and the data was analysed to see the effect of the rain. The results showed decreases in the speed as the rain intensity increased. Similarly, the traffic flow rates decreased as the rain intensity increased. This trend was observed for both peak and non-peak periods and for both directions. It is concluded that the effect of rain during peak period could have more serious consequences on the traffic flow than during non-peak periods because of the higher flow rates and the constrained nature of the flow. Consequently, capacity degradations up to 30% during peak periods would require resources to be employed to manage the traffic.

  18. Philosophical Foundation of Chinese Modernity and the Development of Chinese Philosophy in Recent 100 Years%中华现代性的哲学奠基与百年来的中国哲学

    Institute of Scientific and Technical Information of China (English)

    沈清松

    2013-01-01

    提本文关心的问题在于“中华现代性”的哲学奠基,并扣紧此一思路将百年来的中国哲学发展分为四个阶段。第一阶段,哲学作为西方现代性基础思想之引进者,最领风骚。第二阶段,哲学协助反思民族精神,虽渐退居第二线,然已开始思索中华现代性的方向。第三阶段,哲学工作者致力提出数个融合中西的哲学体系,试图为中华现代性作哲学奠基,在人文、社会科学界中实属难能可贵。现在,处于第四期后期,中国哲学面对全球化与后现代挑战,应能在跨文化与全世界脉络中继续探辟概念系统、生活世界与中华精神资源,进行批判性、合理性、顾全整体的哲学思索。%Focusing on the problematics of Chinese modernity and its philosophical foundation, this paper divides the development of philosophy in China in recent 100 years into four peroiods.In its first period, from 1911 to 1927, philosophers in China were the most enthusiastic in introdu-cing Western modernity and its philosophical foundations from various forms and doctrines of modern Western philosophy.This period was the most pro-gressive and, indeed, impacted all Chinese intellectuals at the time.In its second period from 1928 to 1949, during the time of national construction and the Japanese invasion, philosophers stepped behind, serving as helpers in clarifying and articulating the Chinese spirit and Chinese subjectivity at the time of its awakening.This prepared for the philosophical foundation of a Chinese model of modernity.In the third period from 1949 to 1980, some major philosophical figures had built their philosophical systems synthesizing Western and Chinese philosophies.This was, indeed, most precious, and also unique, in comparison with other disciplines in the humanities and the social sciences.These philosophical systems could be seen as divers at-tempts to lay the philosophical foundation of Chinese

  19. Consequences in Norway after a hypothetical accident at Sellafield - Predicted impacts on the environment

    Energy Technology Data Exchange (ETDEWEB)

    Thoerring, H.; Ytre-Eide, M.A.; Liland, A.

    2010-12-15

    This report describes the possible environmental consequences for Norway due to a hypothetical accident at the Sellafield complex in the UK. The scenario considered involves an explosion and fire at the B215 facility resulting in a 1 % release of the total HAL (Highly Active liquor) inventory of radioactive waste with a subsequent air transport and deposition in Norway. Air transport modelling is based on real meteorological data from October 2008 with wind direction towards Norway and heavy precipitation. This weather is considered to be quite representative as typical seasonal weather. Based on this weather scenario, the estimated fallout in Norway will be approx 17 P Bq of caesium-137 which is 7 times higher than the fallout from the Chernobyl accident. The modelled radioactive contamination is linked with data on transfer to the food chain and statistics on production and hunting to assess the consequences for foodstuffs. The investigation has been limited to the terrestrial environment, focussing on wild berries, fungi, and animals grazing unimproved pastures (i.e. various types of game, reindeer, sheep and goats). The predicted consequences are severe - especially in connection to sheep and goat production. Up to 80 % of the lambs in Norway could be exceeding the food intervention levels for radiocaesium the first years after the fallout, with 30-40 % likely to be above for many years. There will, consequently, be a need for extensive countermeasures in large areas for years or even decades involving several hundred thousand animals each year. Large consequences are also expected for reindeer husbandry - the first year in particular due to the time of fallout which is just prior to winter slaughter. The consequences will be most sever for reindeer herding in middle and southern parts of Norway, but problems may reach as far north as Finnmark where we find the majority of Norwegian reindeer production. The consequences for game will mostly depend on the

  20. Climate Risk Informed Decision Analysis: A Hypothetical Application to the Waas Region

    Science.gov (United States)

    Gilroy, Kristin; Mens, Marjolein; Haasnoot, Marjolijn; Jeuken, Ad

    2016-04-01

    More frequent and intense hydrologic events under climate change are expected to enhance water security and flood risk management challenges worldwide. Traditional planning approaches must be adapted to address climate change and develop solutions with an appropriate level of robustness and flexibility. The Climate Risk Informed Decision Analysis (CRIDA) method is a novel planning approach embodying a suite of complementary methods, including decision scaling and adaptation pathways. Decision scaling offers a bottom-up approach to assess risk and tailors the complexity of the analysis to the problem at hand and the available capacity. Through adaptation pathway,s an array of future strategies towards climate robustness are developed, ranging in flexibility and immediacy of investments. Flexible pathways include transfer points to other strategies to ensure that the system can be adapted if future conditions vary from those expected. CRIDA combines these two approaches in a stakeholder driven process which guides decision makers through the planning and decision process, taking into account how the confidence in the available science, the consequences in the system, and the capacity of institutions should influence strategy selection. In this presentation, we will explain the CRIDA method and compare it to existing planning processes, such as the US Army Corps of Engineers Principles and Guidelines as well as Integrated Water Resources Management Planning. Then, we will apply the approach to a hypothetical case study for the Waas Region, a large downstream river basin facing rapid development threatened by increased flood risks. Through the case study, we will demonstrate how a stakeholder driven process can be used to evaluate system robustness to climate change; develop adaptation pathways for multiple objectives and criteria; and illustrate how varying levels of confidence, consequences, and capacity would play a role in the decision making process, specifically

  1. Simulation of a hypothetical core disruptive accident in the mars test-facility

    Energy Technology Data Exchange (ETDEWEB)

    Robbe, M.F.; Lepareux, M. [CEA Saclay, Dept. de Mecanique et de Technologie, 91 - Gif-sur-Yvette (France)

    2001-07-01

    In France, a large experimental programme MARA/MARS was undertaken in the 80's to estimate the mechanical consequences of an HCDA (Hypothetical Core Disruptive Accident) and to validate the SIRIUS computer code used at that time for the numerical simulations. At the end of the 80's, it was preferred to add a HCDA sodium-bubble-argon tri-component constitutive law to the general ALE fast dynamics finite element CASTEM-PLEXUS code rather than going on developing and using the specialized SIRIUS code. The experimental results of the MARA programme were used in the 90's to validate and qualify the CASTEM-PLEXUS code. A first series of computations of the tests MARA 8, MARA 10 and MARS was realised. The simulations showed a rather good agreement between the experimental and computed results for the MARA 8 and MARA 10 tests - even if there were some discrepancies - but the prediction of the MARS structure displacements and strains was overestimated. This conservatism was supposed to come from the fact that several MARS non axisymmetric structures like core elements, pumps and heat exchangers were not represented in the CASTEM-PLEXUS model. These structures, acting as porous barriers, had a protective effect on the mock-up containment by absorbing energy and slowing down the fluid impacting the containment. For these reasons, we developed in CASTEM-PLEXUS a new HCDA constitutive law taking into account the presence of the internal structures (without meshing them) by means of an equivalent porosity method. In other respects, the process used for dealing with the fluid-structure coupling in CASTEM-PLEXUS was improved. Thus a second series of simulations of the tests MARA8 and MARA10 was realised. A simulation of the test MARS was carried out too with the same simplified representation of the peripheral structures as in order to estimate the improvement provided by the new fluid-structure coupling. This paper presents a third numerical simulation of the MARS

  2. Electromechanical Peak Devices of Distributed Power Generation

    Directory of Open Access Journals (Sweden)

    S. V. Konstantinova

    2011-01-01

    Full Text Available The power world crises (1973, 1979 have demonstrated that mankind entered the expensive energy epoch. More and more attitude is given to power saving problem by including renewable power sources in energy balance of the countries. The paper analyzes a power system inBelarusand a typical chart of the active load is cited in the paper. Equalization of load chart is considered as one of measures directed on provision of higher operational efficiency of power system and power saving.  This purpose can be obtained while including electromechanical peak devices of the distributed generation in the energy balance.

  3. LARAMIE PEAK WILDERNESS STUDY AREA, WYOMING.

    Science.gov (United States)

    Segerstrom, Kenneth; Weisner, R.C.

    1984-01-01

    On the basis of a mineral survey, most of the Laramie Peak Wilderness study area in Wyoming was concluded to have little promise for the occurrence of mineral or energy resources. Only three small areas in the northern part, one extending outside the study area to Esterbrook, were found to have probable mineral-resource potential for copper and lead. The geologic setting precludes the presence of fossil-fuel resources in the study area. There are no surface indications that geothermal energy could be developed within or near the study area.

  4. Forecasting peaks of seasonal influenza epidemics.

    Science.gov (United States)

    Nsoesie, Elaine; Mararthe, Madhav; Brownstein, John

    2013-06-21

    We present a framework for near real-time forecast of influenza epidemics using a simulation optimization approach. The method combines an individual-based model and a simple root finding optimization method for parameter estimation and forecasting. In this study, retrospective forecasts were generated for seasonal influenza epidemics using web-based estimates of influenza activity from Google Flu Trends for 2004-2005, 2007-2008 and 2012-2013 flu seasons. In some cases, the peak could be forecasted 5-6 weeks ahead. This study adds to existing resources for influenza forecasting and the proposed method can be used in conjunction with other approaches in an ensemble framework.

  5. Peak oil, economic growth, and wildlife conservation

    CERN Document Server

    Gates, J Edward; Czech, Brian

    2014-01-01

    The proposed book focuses on one of the most important issues affecting humankind in this century - Peak Oil or the declining availability of abundant, cheap energy-and its effects on our industrialized economy and wildlife conservation. Energy will be one of the defining issues of the 21st Century directly affecting wildlife conservation wherever energy extraction is a primary economic activity and indirectly through deepening economic recessions. Since cheap, abundant energy has been at the core of our industrial society, and has resulted in the technological advancements we enjoy today, the

  6. Particle creation by peak electric field

    CERN Document Server

    Adorno, T C; Gitman, D M

    2016-01-01

    The particle creation by the so-called peak electric field is considered. The latter field is a combination of two exponential parts, one exponentially-increasing and another exponentially-decreasing. We find exact solutions of the Dirac equation with the field under consideration with appropriate asymptotic conditions and calculate all the characteristics of particle creation effect, in particular, differential mean numbers of created particle, total number of created particles, and the probability for a vacuum to remain a vacuum. Characteristic asymptotic regimes are discussed in detail and a comparison with the pure asymptotically decaying field is considered.

  7. Particle creation by peak electric field

    Energy Technology Data Exchange (ETDEWEB)

    Adorno, T.C. [Tomsk State University, Department of Physics, Tomsk (Russian Federation); Gavrilov, S.P. [Tomsk State University, Department of Physics, Tomsk (Russian Federation); Herzen State Pedagogical University of Russia, Department of General and Experimental Physics, St. Petersburg (Russian Federation); Gitman, D.M. [Tomsk State University, Department of Physics, Tomsk (Russian Federation); P. N. Lebedev Physical Institute, Moscow (Russian Federation); University of Sao Paulo, Institute of Physics, CP 66318, Sao Paulo, SP (Brazil)

    2016-08-15

    The particle creation by the so-called peak electric field is considered. The latter field is a combination of two exponential parts, one exponentially increasing and another exponentially decreasing. We find exact solutions of the Dirac equation with the field under consideration with appropriate asymptotic conditions and calculate all the characteristics of particle creation effect, in particular, differential mean numbers of created particle, total number of created particles, and the probability for a vacuum to remain a vacuum. Characteristic asymptotic regimes are discussed in detail and a comparison with the pure asymptotically decaying field is considered. (orig.)

  8. In-silico prediction of dual function of DksA like hypothetical protein in V. cholerae O395 genome.

    Science.gov (United States)

    Dutta, Avirup; Katarkar, Atul; Chaudhuri, Keya

    2017-01-01

    Cholera, an acute infection of the small intestine, is caused by Vibrio cholerae. The present study identified a hypothetical protein in V. cholerae O395, which was predicted to be acquired through horizontal gene transfer the origin of which was found to be from a phage. Its expression was further confirmed by RT-PCR. Homology based 3D model of the hypothetical protein indicated DksA like homologue. Protein binding site of 3D-model revealed a deep cleft which may influence the dimer formation and interaction with ds-DNA molecule. Also, canonical function of direct interaction with RNA polymerase (RNAP) holoenzyme in complex with ppGpp suggests its dual role in the pathogenesis of cholera.

  9. Springfield Processing Plant* (A Hypothetical Facility) SPP, Entry Control Point and Vehicle Gate Access Control Post Order

    Energy Technology Data Exchange (ETDEWEB)

    Baum, Gregory A. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2014-06-01

    This hypothetical order provides the requirements and instructions for the Springfield Processing Plant (SPP) Vehicle Gate and Entry Control Point (ECP) in the perimeter access building. The purpose of this post is to prevent the theft, sabotage or diversion of nuclear material (NM), control access and exit at the protected area, and to respond to emergencies according the SPP Guard Force (GF) Contingency Plan and as directed by a Guard Force Supervisor.

  10. Beyond the Peak - Tactile Temporal Discrimination Does Not Correlate with Individual Peak Frequencies in Somatosensory Cortex.

    Science.gov (United States)

    Baumgarten, Thomas J; Schnitzler, Alfons; Lange, Joachim

    2017-01-01

    The human sensory systems constantly receive input from different stimuli. Whether these stimuli are integrated into a coherent percept or segregated and perceived as separate events, is critically determined by the temporal distance of the stimuli. This temporal distance has prompted the concept of temporal integration windows or perceptual cycles. Although this concept has gained considerable support, the neuronal correlates are still discussed. Studies suggested that neuronal oscillations might provide a neuronal basis for such perceptual cycles, i.e., the cycle lengths of alpha oscillations in visual cortex and beta oscillations in somatosensory cortex might determine the length of perceptual cycles. Specifically, recent studies reported that the peak frequency (the frequency with the highest spectral power) of alpha oscillations in visual cortex correlates with subjects' ability to discriminate two visual stimuli. In the present study, we investigated whether peak frequencies in somatosensory cortex might serve as the correlate of perceptual cycles in tactile discrimination. Despite several different approaches, we were unable to find a significant correlation between individual peak frequencies in the alpha- and beta-band and individual discrimination abilities. In addition, analysis of Bayes factor provided evidence that peak frequencies and discrimination thresholds are unrelated. The results suggest that perceptual cycles in the somatosensory domain are not necessarily to be found in the peak frequency, but in other frequencies. We argue that studies based solely on analysis of peak frequencies might thus miss relevant information.

  11. PeakVizor: Visual Analytics of Peaks in Video Clickstreams from Massive Open Online Courses.

    Science.gov (United States)

    Chen, Qing; Chen, Yuanzhe; Liu, Dongyu; Shi, Conglei; Wu, Yingcai; Qu, Huamin

    2016-10-01

    Massive open online courses (MOOCs) aim to facilitate open-access and massive-participation education. These courses have attracted millions of learners recently. At present, most MOOC platforms record the web log data of learner interactions with course videos. Such large amounts of multivariate data pose a new challenge in terms of analyzing online learning behaviors. Previous studies have mainly focused on the aggregate behaviors of learners from a summative view; however, few attempts have been made to conduct a detailed analysis of such behaviors. To determine complex learning patterns in MOOC video interactions, this paper introduces a comprehensive visualization system called PeakVizor. This system enables course instructors and education experts to analyze the "peaks" or the video segments that generate numerous clickstreams. The system features three views at different levels: the overview with glyphs to display valuable statistics regarding the peaks detected; the flow view to present spatio-temporal information regarding the peaks; and the correlation view to show the correlation between different learner groups and the peaks. Case studies and interviews conducted with domain experts have demonstrated the usefulness and effectiveness of PeakVizor, and new findings about learning behaviors in MOOC platforms have been reported.

  12. Confirmation of the Expression of a Large Set of Conserved Hypothetical Proteins in Shewanella oneidensis MR-1

    Energy Technology Data Exchange (ETDEWEB)

    Elias, Dwayne A.; Monroe, Matthew E.; Smith, Richard D.; Fredrickson, Jim K.; Lipton, Mary S.

    2006-08-01

    High-throughput “omic” technologies have allowed for a relatively rapid, yet comprehensive analysis of the global expression patterns within an organism in response to perturbations. In the current study, tryptic peptides were identified with high confidence from capillary liquid chromatography-mass spectrometry analysis of 26 chemostat cultures of Shewanella oneidensis MR-1 under various conditions. Using at least one distinctive and a total of two total peptide identifications per protein, we detected the expression of 758 conserved hypothetical proteins. This included 359 such proteins previously described (Kolker et al, 2005) with an additional 399 reported herein for the first time. The latter 399 proteins ranged from 5.3 to 208.3 kDa, with 44 being of 100 amino acid residues or less. Using a combination of information including peptide detection in cells grown under specific culture conditions and predictive algorithms such as PSORT and PSORT-B, possible/plausible functions are proposed for some conserved hypothetical proteins. Such proteins were found not only to be expressed, but 19 were only expressed under certain culturing conditions, thereby providing insight into potential functions. These findings also impact the genomic annotation for S. oneidensis MR-1 by confirming that these genes code for expressed proteins. Our results indicate that 399 proteins can now be upgraded from “conserved hypothetical protein” to “expressed protein in Shewanella,” 19 of which appeared to be expressed under specific culture conditions.

  13. Statistical equivalence and test-retest reliability of delay and probability discounting using real and hypothetical rewards.

    Science.gov (United States)

    Matusiewicz, Alexis K; Carter, Anne E; Landes, Reid D; Yi, Richard

    2013-11-01

    Delay discounting (DD) and probability discounting (PD) refer to the reduction in the subjective value of outcomes as a function of delay and uncertainty, respectively. Elevated measures of discounting are associated with a variety of maladaptive behaviors, and confidence in the validity of these measures is imperative. The present research examined (1) the statistical equivalence of discounting measures when rewards were hypothetical or real, and (2) their 1-week reliability. While previous research has partially explored these issues using the low threshold of nonsignificant difference, the present study fully addressed this issue using the more-compelling threshold of statistical equivalence. DD and PD measures were collected from 28 healthy adults using real and hypothetical $50 rewards during each of two experimental sessions, one week apart. Analyses using area-under-the-curve measures revealed a general pattern of statistical equivalence, indicating equivalence of real/hypothetical conditions as well as 1-week reliability. Exceptions are identified and discussed. Copyright © 2013 Elsevier B.V. All rights reserved.

  14. Peak heart rates at extreme altitudes

    DEFF Research Database (Denmark)

    Lundby, C; Van Hall, Gerrit

    2001-01-01

    We have measured maximal heart rate during a graded maximal bicycle exercise test to exhaustion in five healthy climbers before and during an expedition to Mt. Everest. Maximal heart rates at sea level were 186 (177-204) beats/min(-1) at sea level and 170 (169-182) beats/min(-1) with acute hypoxia....... After 1, 4 and 6 weeks of acclimatization to 5400 m, maximal heart rates were 155 (135-182), 158 (144-182), and 155 (140-183) beats/min(-1), respectively. Heart rates of two of the climbers were measured during their attempt to reach the summit of Mt. Everest without the use of supplemental oxygen....... The peak heart rates at 8,750 m for the two climbers were 142 and 144 beats/min(-1), which were similar to their maximal heart rates during exhaustive bicycle exercise at 5,400 m, the values being 144 and 148 beats/min(-1), respectively. The peak heart rates at 8,750 m are in agreement with other field...

  15. Equivalence Principle and the Baryon Acoustic Peak

    CERN Document Server

    Baldauf, Tobias; Simonović, Marko; Zaldarriaga, Matias

    2015-01-01

    We study the dominant effect of a long wavelength density perturbation $\\delta(\\lambda_L)$ on short distance physics. In the non-relativistic limit, the result is a uniform acceleration, fixed by the equivalence principle, and typically has no effect on statistical averages due to translational invariance. This same reasoning has been formalized to obtain a "consistency condition" on the cosmological correlation functions. In the presence of a feature, such as the acoustic peak at $l_{\\rm BAO}$, this naive expectation breaks down for $\\lambda_Lpeak, and is calculable to all orders in the long modes. This can be used to improve the result of perturbative calculations - a technique known as "infra-red resummation"- and is explicitly applied to the one-loop calculation of power spectrum. Finally, the success of BAO reconstruction schemes is argue...

  16. Microwave peak absorption frequency of liquid

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Microwave-assisted extraction is a new effective method which has practical ap-plications in many fields. Microwave heating is one of its physical mechanisms,and it also has the characteristic of selectivity. When the applied microwave fre-quency equals a certain absorption frequency of the material (or specific compo-nent),the material will intensively absorb microwave energy. This is also known as resonant absorption,and the frequency is called the peak absorption frequency which depends on the physical structure of the material. In this work,dynamic hy-drogen bond energy was included in molecular activation energy; with the liquid cell model,the expression of interaction energy between dipolar molecules was derived. The rotational relaxation time was gotten from the Eyring viscosity formula. Then based on the relationship between dielectric dissipation coefficient and re-laxation time,the expression of microwave peak absorption frequency as a func-tion of the material physical structure,rotational inertia and electrical dipole mo-ment of molecules was established. These theoretical formulas were applied to water and benzene,and the calculated results agree fairly well with the experi-mental data. This work can not only deepen the study of the interaction between microwave and material,but also provide a possible guide for the experiment of microwave-assisted extraction.

  17. Microwave peak absorption frequency of liquid

    Institute of Scientific and Technical Information of China (English)

    HAN GuangZe; CHEN MingDong

    2008-01-01

    Microwave-assisted extraction is a new effective method which has practical ap-plications in many fields. Microwave heating is one of its physical mechanisms, and it also has the characteristic of selectivity. When the applied microwave fre-quency equals a certain absorption frequency of the material (or specific compo-nent), the material will intensively absorb microwave energy. This is also known as resonant absorption, and the frequency is called the peak absorption frequency which depends on the physical structure of the material. In this work, dynamic hy-drogen bond energy was included in molecular activation energy; with the liquid cell model, the expression of interaction energy between dipolar molecules was derived. The rotational relaxation time was gotten from the Eyring viscosity formula. Then based on the relationship between dielectric dissipation coefficient and re-laxation time, the expression of microwave peak absorption frequency as a func-tion of the material physical structure, rotational inertia and electrical dipole mo-ment of molecules was established. These theoretical formulas were applied to water and benzene, and the calculated results agree fairly well with the experi-mental data. This work can not only deepen the study of the interaction between microwave and material, but also provide a possible guide for the experiment of microwave-assisted extraction.

  18. Method and apparatus for current-output peak detection

    Energy Technology Data Exchange (ETDEWEB)

    De Geronimo, Gianluigi

    2017-01-24

    A method and apparatus for a current-output peak detector. A current-output peak detector circuit is disclosed and works in two phases. The peak detector circuit includes switches to switch the peak detector circuit from the first phase to the second phase upon detection of the peak voltage of an input voltage signal. The peak detector generates a current output with a high degree of accuracy in the second phase.

  19. , Recorded at Ladron Peak, Central New Mexico

    Science.gov (United States)

    Ricketts, J. W.; Kelley, S.; Read, A. S.; Karlstrom, K. E.

    2010-12-01

    Ladron Peak, situated on the western flank of the Rio Grande rift ~30 miles NW of Socorro, NM, is composed of Precambrian granitic and metamorphic assemblages that have been faulted and uplifted during the late Tertiary formation of the rift. The area is bounded on three sides by normal faults, including the anomalously low-angle (~26°) Jeter fault to the east, which places Precambrian rocks in the footwall against Paleozoic and Mesozoic fault slivers, and mainly Cenozoic Santa Fe Group basin fill in the hanging wall. New apatite fission track (AFT) thermochronological data collected at 22 locations along the NE and SE margins of Ladron Peak give a range of ages from 10.9 ± 1.9 to 20.4 ± 8.6 Ma. Samples within the footwall include granitic and metasedimentary rocks that have mean track lengths of 13.1 to 14.1 μm; one quartzite sample has a mean track length of 12.5 μm, suggesting time in the partial annealing zone. Within the hanging wall block, new AFT ages from the Permian Bursum and Abo Formations give cooling ages of 23.1 ± 3.3 Ma. and 59.9 ± 12.4 Ma., respectively. The Bursum Formation sample, with a track length of 13.7 μm, cooled below the 110°C isotherm during the Miocene, while the Abo Formation sample, with a track length of 11.2 μm, was only partially reset prior to rift-related deformation. Mylonitized granitic and metamorphic rocks in the immediate footwall preserve dip-slip lineations that are parallel to slip on the Jeter fault. This suggests that strain associated with exhumation was recorded by both brittle and ductile deformation. Although this type of deformation is common within metamorphic core complexes in highly extended terranes, ductile normal faulting has not been recognized within the Rio Grande rift in New Mexico, though there is some suggestion of ductile deformation around Blanca Peak in the San Luis Valley in Colorado. These observations imply one or both of the following: (1) Ductile deformation at Ladron Peak was

  20. Nutrient Dynamics over the Past 100 Years and Its Restoration Baseline in Dianshan Lake%淀山湖百年营养演化历史及营养物基准的建立

    Institute of Scientific and Technical Information of China (English)

    李小平; 陈小华; 董旭辉; 董志; 孙敦平

    2012-01-01

    Cyclotella bodanica,C.ocelata,Achnanthes minutissima,Cocconeis placentula var lineate,Cymbella sp.,Fragilaria piata,F.brevistrata,F.construens var venter to recent eutrophic species including Cyclostephanos dubius,C.atomus,Stephanodiscus minitulus,S.hantzschi,Aulacoseria alpigena.The epilimnetic TP over the past 100 years reconstructed using an established diatom-TP transfer function matches well with the monitoring TP where exists.Based on the sedimentary nutrient characteristics and diatom-reconstructed nutrient dynamics,we proposed that the nutrient baseline for Dianshan Lake is 50-60 μg·L-1,500 mg·kg-1 and 550 mg·kg-1 for water TP concentration,sedimentary TP and TN,respectively.

  1. Peak Wind Tool for General Forecasting

    Science.gov (United States)

    Barrett, Joe H., III

    2010-01-01

    The expected peak wind speed of the day is an important forecast element in the 45th Weather Squadron's (45 WS) daily 24-Hour and Weekly Planning Forecasts. The forecasts are used for ground and space launch operations at the Kennedy Space Center (KSC) and Cape Canaveral Air Force Station (CCAFS). The 45 WS also issues wind advisories for KSC/CCAFS when they expect wind gusts to meet or exceed 25 kt, 35 kt and 50 kt thresholds at any level from the surface to 300 ft. The 45 WS forecasters have indicated peak wind speeds are challenging to forecast, particularly in the cool season months of October - April. In Phase I of this task, the Applied Meteorology Unit (AMU) developed a tool to help the 45 WS forecast non-convective winds at KSC/CCAFS for the 24-hour period of 0800 to 0800 local time. The tool was delivered as a Microsoft Excel graphical user interface (GUI). The GUI displayed the forecast of peak wind speed, 5-minute average wind speed at the time of the peak wind, timing of the peak wind and probability the peak speed would meet or exceed 25 kt, 35 kt and 50 kt. For the current task (Phase II ), the 45 WS requested additional observations be used for the creation of the forecast equations by expanding the period of record (POR). Additional parameters were evaluated as predictors, including wind speeds between 500 ft and 3000 ft, static stability classification, Bulk Richardson Number, mixing depth, vertical wind shear, temperature inversion strength and depth and wind direction. Using a verification data set, the AMU compared the performance of the Phase I and II prediction methods. Just as in Phase I, the tool was delivered as a Microsoft Excel GUI. The 45 WS requested the tool also be available in the Meteorological Interactive Data Display System (MIDDS). The AMU first expanded the POR by two years by adding tower observations, surface observations and CCAFS (XMR) soundings for the cool season months of March 2007 to April 2009. The POR was expanded

  2. Assessment of environmental public exposure from a hypothetical nuclear accident for Unit-1 Bushehr nuclear power plant.

    Science.gov (United States)

    Sohrabi, M; Ghasemi, M; Amrollahi, R; Khamooshi, C; Parsouzi, Z

    2013-05-01

    Unit-1 of the Bushehr nuclear power plant (BNPP-1) is a VVER-type reactor with 1,000-MWe power constructed near Bushehr city at the coast of the Persian Gulf, Iran. The reactor has been recently operational to near its full power. The radiological impact of nuclear power plant (NPP) accidents is of public concern, and the assessment of radiological consequences of any hypothetical nuclear accident on public exposure is vital. The hypothetical accident scenario considered in this paper is a design-basis accident, that is, a primary coolant leakage to the secondary circuit. This scenario was selected in order to compare and verify the results obtained in the present paper with those reported in the Final Safety Analysis Report (FSAR 2007) of the BNPP-1 and to develop a well-proven methodology that can be used to study other and more severe hypothetical accident scenarios for this reactor. In the present study, the version 2.01 of the PC COSYMA code was applied. In the early phase of the accidental releases, effective doses (from external and internal exposures) as well as individual and collective doses (due to the late phase of accidental releases) were evaluated. The surrounding area of the BNPP-1 within a radius of 80 km was subdivided into seven concentric rings and 16 sectors, and distribution of population and agricultural products was calculated for this grid. The results show that during the first year following the modeled hypothetical accident, the effective doses do not exceed the limit of 5 mSv, for the considered distances from the BNPP-1. The results obtained in this study are in good agreement with those in the FSAR-2007 report. The agreement obtained is in light of many inherent uncertainties and variables existing in the two modeling procedures applied and proves that the methodology applied here can also be used to model other severe hypothetical accident scenarios of the BNPP-1 such as a small and large break in the reactor coolant system as well

  3. Peak Electric Load Relief in Northern Manhattan

    Directory of Open Access Journals (Sweden)

    Hildegaard D. Link

    2014-08-01

    Full Text Available The aphorism “Think globally, act locally,” attributed to René Dubos, reflects the vision that the solution to global environmental problems must begin with efforts within our communities. PlaNYC 2030, the New York City sustainability plan, is the starting point for this study. Results include (a a case study based on the City College of New York (CCNY energy audit, in which we model the impacts of green roofs on campus energy demand and (b a case study of energy use at the neighborhood scale. We find that reducing the urban heat island effect can reduce building cooling requirements, peak electricity loads stress on the local electricity grid and improve urban livability.

  4. Tim Peake and Britain's road to space

    CERN Document Server

    Seedhouse, Erik

    2017-01-01

    This book puts the reader in the flight suit of Britain’s first male astronaut, Tim Peake. It chronicles his life, along with the Principia mission and the down-to-the-last-bolt descriptions of life aboard the ISS, by way of the hurdles placed by the British government and the rigors of training at Russia’s Star City military base. In addition, this book discusses the learning curves required in astronaut and mission training and the complexity of the technologies required to launch an astronaut and keep them alive for months on end. This book underscores the fact that technology and training, unlike space, do not exist in a vacuum; complex technical systems, like the ISS, interact with the variables of human personality, and the cultural background of the astronauts. .

  5. Peak, multi-peak and broadband absorption in graphene-based one-dimensional photonic crystal

    Science.gov (United States)

    Miloua, R.; Kebbab, Z.; Chiker, F.; Khadraoui, M.; Sahraoui, K.; Bouzidi, A.; Medles, M.; Mathieu, C.; Benramdane, N.

    2014-11-01

    We theoretically investigate the possibility of enhancing light absorption in graphene-based one dimensional photonic crystal. We demonstrate that it is possible to achieve total light absorption at technologically important wavelengths using one-dimensional graphene-based photonic crystals. By means of the transfer matrix method, we investigate the effect of refractive indices and layer numbers on the optical response of the structure. We found that it is possible to achieve one peak, multi-peak or broadband, and complete optical absorption. As a result, the proposed photonic structures enable myriad potential applications such as photodetection, shielding and optical sensing.

  6. Norwegian hydropower a valuable peak power source

    Energy Technology Data Exchange (ETDEWEB)

    Brekke, Hermod

    2010-07-01

    given on a possible increase of the Norwegian hydropower peak power production to meet the growing the European demand for peak power caused by the growing non stationary production from wind mills and ocean energy from waves and sea current. Also building of reversible pump turbine power plants will be discussed even if approximately 10% power will be consumed by loss in the pumping phase compared to direct use of the water from reservoirs. (Author)

  7. Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality

    DEFF Research Database (Denmark)

    Pundhir, Sachin; Bagger, Frederik Otzen; Lauridsen, Felicia Kathrine Bratt

    2016-01-01

    Formation of nucleosome free region (NFR) accompanied by specific histone modifications at flanking nucleosomes is an important prerequisite for enhancer and promoter activity. Due to this process, active regulatory elements often exhibit a distinct shape of histone signal in the form of a peak...

  8. Peak phosphorus - peak food? The need to close the phosphorus cycle.

    Science.gov (United States)

    Rhodes, Christopher J

    2013-01-01

    The peak in the world production of phosphorus has been predicted to occur in 2033, based on world reserves of rock phosphate (URR) reckoned at around 24,000 million tonnes (Mt), with around 18,000 Mt remaining. This figure was reckoned-up to 71,000 Mt, by the USGS, in 2012, but a production maximum during the present century is still highly probable. There are complex issues over what the demand will be for phosphorus in the future, as measured against a rising population (from 7 billion to over 9 billion in 2050), and a greater per capita demand for fertiliser to grow more grain, in part to feed animals and meet a rising demand for meat by a human species that is not merely more populous but more affluent. As a counterweight to this, we may expect that greater efficiencies in the use of phosphorus - including recycling from farms and of human and animal waste - will reduce the per capita demand for phosphate rock. The unseen game changer is peak oil, since phosphate is mined and recovered using machinery powered by liquid fuels refined from crude oil. Hence, peak oil and peak phosphorus might appear as conjoined twins. There is no unequivocal case that we can afford to ignore the likelihood of a supply-demand gap for phosphorus occurring sometime this century, and it would be perilous to do so.

  9. Analysis of the Peak Resistance Frequency Method.

    Science.gov (United States)

    Wang, Boshuo; Weiland, James D

    2016-10-01

    This study analyzes the peak resistance frequency (PRF) method described by Mercanzini et al., a method that can easily extract the tissue resistance from impedance spectroscopy for many neural engineering applications but has no analytical description thus far. Mathematical analyses and computer simulations were used to explore underlying principles, accuracy, and limitations of the PRF method. The mathematical analyses demonstrated that the PRF method has an inherent but correctable deviation dependent on the idealness of the electrode-tissue interface, which is validated by simulations. Further simulations show that both frequency sampling and noise affect the accuracy of the PRF method, and in general, it performs less accurately than least squares methods. However, the PRF method achieves simplicity and reduced measurement and computation time at the expense of accuracy. From the qualitative results, the PRF method can work with reasonable precision and simplicity, although its limitation and the idealness of the electrode-tissue interface involved should be taken into consideration. This paper provides a mathematical foundation for the PRF method and its practical implementation.

  10. Z-peaked excess in goldstini scenarios

    CERN Document Server

    Liew, Seng Pei; Mawatari, Kentarou; Sakurai, Kazuki; Vereecken, Matthias

    2015-01-01

    We study a possible explanation of a 3.0 $\\sigma$ excess recently reported by the ATLAS Collaboration in events with Z-peaked same-flavour opposite-sign lepton pair, jets and large missing transverse momentum in the context of gauge-mediated SUSY breaking with more than one hidden sector, the so-called goldstini scenario. In a certain parameter space, the gluino two-body decay chain $\\tilde g\\to g\\tilde\\chi^0_{1,2}\\to gZ\\tilde G'$ becomes dominant, where $\\tilde\\chi^0_{1,2}$ and $\\tilde G'$ are the Higgsino-like neutralino and the massive pseudo-goldstino, respectively, and gluino pair production can contribute to the signal. We find that a mass spectrum such as $m_{\\tilde g}\\sim 900$ GeV, $m_{\\tilde\\chi^0_{1,2}}\\sim 700$ GeV and $m_{\\tilde G'}\\sim 600$ GeV demonstrates the rate and the distributions of the excess, without conflicting with the stringent constraints from jets plus missing energy analyses and with the CMS constraint on the identical final state.

  11. Z-peaked excess in goldstini scenarios

    Directory of Open Access Journals (Sweden)

    Seng Pei Liew

    2015-11-01

    Full Text Available We study a possible explanation of a 3.0 σ excess recently reported by the ATLAS Collaboration in events with Z-peaked same-flavour opposite-sign lepton pair, jets and large missing transverse momentum in the context of gauge-mediated SUSY breaking with more than one hidden sector, the so-called goldstini scenario. In a certain parameter space, the gluino two-body decay chain g˜→gχ˜1,20→gZG˜′ becomes dominant, where χ˜1,20 and G˜′ are the Higgsino-like neutralino and the massive pseudo-goldstino, respectively, and gluino pair production can contribute to the signal. We find that a mass spectrum such as mg˜∼1000 GeV, mχ˜1,20∼800 GeV and mG˜′∼600 GeV demonstrates the rate and the distributions of the excess, without conflicting with the stringent constraints from jets plus missing energy analyses and with the CMS constraint on the identical final state.

  12. Asymmetry parameter of peaked Fano line shapes

    Science.gov (United States)

    Meierott, S.; Hotz, T.; Néel, N.; Kröger, J.

    2016-10-01

    The spectroscopic line shape of electronic and vibrational excitations is ubiquitously described by a Fano profile. In the case of nearly symmetric and peaked Fano line shapes, the fit of the conventional Fano function to experimental data leads to difficulties in unambiguously extracting the asymmetry parameter, which may vary over orders of magnitude without degrading the quality of the fit. Moreover, the extracted asymmetry parameter depends on initially guessed values. Using the spectroscopic signature of the single-Co Kondo effect on Au(110) the ambiguity of the extracted asymmetry parameter is traced to the highly symmetric resonance profile combined with the inevitable scattering of experimental data. An improved parameterization of the conventional Fano function is suggested that enables the nonlinear optimization in a reduced parameter space. In addition, the presence of a global minimum in the sum of squared residuals and thus the independence of start parameters may conveniently be identified in a two-dimensional plot. An angular representation of the asymmetry parameter is suggested in order to reliably determine uncertainty margins via linear error propagation.

  13. A Qualitative Analysis of the Effects of Victimization History and Sexual Attitudes on Women's Hypothetical Sexual Assault Scripts.

    Science.gov (United States)

    Leiting, Kari A; Yeater, Elizabeth A

    2017-01-01

    This study examined qualitatively the effects of a sexual victimization history and sexual attitudes on 247 undergraduate women's written accounts of a hypothetical sexual assault. More severe victimization history was associated with script characteristics of greater alcohol use, knowing the man longer, and the context of a party. Greater endorsement of positive attitudes toward casual sex was related to script characteristics of greater alcohol use, acquiescing to the man, and not knowing the man as long. Finally, a more recent sexual assault was associated with script characteristics of having just met the man, the context of a party or date, and acquiescing to the man.

  14. An approach for estimating the radiological significance of a hypothetical major nuclear accident over long distance transboundary scales

    Energy Technology Data Exchange (ETDEWEB)

    Mitrakos, D., E-mail: dimitris.mitrakos@eeae.gr; Potiriadis, C.; Housiadas, C.

    2016-04-15

    Highlights: • Actions may be warranted after a major nuclear accident even at long distances. • Distance may not be the decisive parameter for longer term radiological impact. • Remote impact may vary orders of magnitude depending on the meteorological conditions. • The potential impact can be assessed using computationally inexpensive calculations. - Abstract: After the Fukushima accident important initiatives were taken in European level to enhance the nuclear safety level of the existing and planned nuclear reactors, such as the so-called nuclear “stress-tests” and the amendment of the Nuclear Safety Directive. A recent work of HERCA and WENRA focused on the need for a more consistent and harmonized response in a transboundary context in case of a hypothetical major nuclear accident in Europe. Such an accident, although very improbable, cannot be totally excluded and so, should be considered in emergency preparedness arrangements among the various European countries. In case of a hypothetical severe Fukushima-like accident in Europe, the role of the neighboring countries may be important, since the authorities should be able to provide information and advice to the government and the public, but also can contribute to the overall assessment of the situation be their own means. In this work we assess the radiological significance of a hypothetical major nuclear accident for distances longer than 300 km that are not typically covered by the internationally accepted emergency planning zones. The approach is simple and computationally inexpensive, since it is based on the calculation of only a few release scenarios at dates selected within a whole year on the basis of bounding the deposition levels at long distances in relation to the occurrence of precipitation. From the calculated results it is evident that distance is not the only decisive parameter in estimating the potential radiological significance of a severe nuclear accident. The hypothetical

  15. Potential consequences in Norway after a hypothetical accident at Leningrad nuclear power plant. Potential release, fallout and predicted impacts on the environment

    Energy Technology Data Exchange (ETDEWEB)

    Nalbandyan, A.; Ytre-Eide, M.A.; Thoerring, H.; Liland, A.; Bartnicki, J.; Balonov, M.

    2012-06-15

    The report describes different hypothetical accident scenarios at the Leningrad nuclear power plant for both RBMK and VVER-1200 reactors. The estimated release is combined with different meteorological scenarios to predict possible fallout of radioactive substances in Norway. For a hypothetical catastrophic accident at an RBMK reactor combined with a meteorological worst case scenario, the consequences in Norway could be considerable. Foodstuffs in many regions would be contaminated above the food intervention levels for radioactive cesium in Norway. (Author)

  16. Deduction Theorem and Hypothetical Syllogism Rule on Fuzzy Logic System%模糊逻辑系统中的演绎定理和HS规则

    Institute of Scientific and Technical Information of China (English)

    杨晓斌; 邓书显

    2005-01-01

    Cancelled the first axiom L1) or the third axiom L3) of the classical formal logic system we established two kinds of quasi-formal deductive system, LG*-Rand LG*, respectively. In LG*-R we proved that neither the deduction theorem nor the hypothetical syllogism (HS) rule held but a deduction theorem and an HS rule are obtained in a weak sense. We also proved that both the deduction theorem and the hypothetical syllogism(HS)rule hold in LG*.

  17. An in silico Approach for Structural and Functional Annotation of Salmonella enterica serovar typhimurium Hypothetical Protein R_27

    Directory of Open Access Journals (Sweden)

    Arif Khan

    2016-03-01

    Full Text Available Typhoid fever is a major cause of illness in most developing countries, including Bangladesh. In quest of new potential drug against Typhoid fever, the current study was designed to elucidate structural and functional details of S. typhi hypothetical protein (HP R_27. HP R_27 has the primary amino acid sequences available only. The structural annotation was determined by ProtParam, SOPMA, and CELLO. The three-dimensional (3D structure of HP R_27 predicted through homology modeling by using Phyre2. The 3D structure then refined and verified by ModRefiner, PROCHECK, ERRAT, QMEAN. The functional annotation was also performed by InterProScan, SMART, Pfam, NCBI-CDD and found Phospholipase D-like and DNA repair activity. Multiple sequence alignment also supported the existence of PLD-like domain and DNA repair protein domain in the selected hypothetical protein sequences. Finally, the cavity of drug binding was also identified to assist further molecular docking study and potent inhibitor identification. This in silico approach can be further utilized in molecular drug design for other clinically significant pathogens.

  18. The gene expression data of Mycobacterium tuberculosis based on Affymetrix gene chips provide insight into regulatory and hypothetical genes

    Directory of Open Access Journals (Sweden)

    Fu-Liu Casey S

    2007-05-01

    Full Text Available Abstract Background Tuberculosis remains a leading infectious disease with global public health threat. Its control and management have been complicated by multi-drug resistance and latent infection, which prompts scientists to find new and more effective drugs. With the completion of the genome sequence of the etiologic bacterium, Mycobacterium tuberculosis, it is now feasible to search for new drug targets by sieving through a large number of gene products and conduct genome-scale experiments based on microarray technology. However, the full potential of genome-wide microarray analysis in configuring interrelationships among all genes in M. tuberculosis has yet to be realized. To date, it is only possible to assign a function to 52% of proteins predicted in the genome. Results We conducted a functional-genomics study using the high-resolution Affymetrix oligonucleotide GeneChip. Approximately one-half of the genes were found to be always expressed, including more than 100 predicted conserved hypotheticals, in the genome of M. tuberculosis during the log phase of in vitro growth. The gene expression profiles were analyzed and visualized through cluster analysis to epitomize the full details of genomic behavior. Broad patterns derived from genome-wide expression experiments in this study have provided insight into the interrelationships among genes in the basic cellular processes of M. tuberculosis. Conclusion Our results have confirmed several known gene clusters in energy production, information pathways, and lipid metabolism, and also hinted at potential roles of hypothetical and regulatory proteins.

  19. Personality and Behavior in Social Dilemmas: Testing the Situational Strength Hypothesis and the Role of Hypothetical Versus Real Incentives.

    Science.gov (United States)

    Lozano, José H

    2016-02-01

    Previous research aimed at testing the situational strength hypothesis suffers from serious limitations regarding the conceptualization of strength. In order to overcome these limitations, the present study attempts to test the situational strength hypothesis based on the operationalization of strength as reinforcement contingencies. One dispositional factor of proven effect on cooperative behavior, social value orientation (SVO), was used as a predictor of behavior in four social dilemmas with varying degree of situational strength. The moderating role of incentive condition (hypothetical vs. real) on the relationship between SVO and behavior was also tested. One hundred undergraduates were presented with the four social dilemmas and the Social Value Orientation Scale. One-half of the sample played the social dilemmas using real incentives, whereas the other half used hypothetical incentives. Results supported the situational strength hypothesis in that no behavioral variability and no effect of SVO on behavior were found in the strongest situation. However, situational strength did not moderate the effect of SVO on behavior in situations where behavior showed variability. No moderating effect was found for incentive condition either. The implications of these results for personality theory and assessment are discussed.

  20. Hypothetical scenario exercises to improve planning and readiness for drinking water quality management during extreme weather events.

    Science.gov (United States)

    Deere, Daniel; Leusch, Frederic D L; Humpage, Andrew; Cunliffe, David; Khan, Stuart J

    2017-03-15

    Two hypothetical scenario exercises were designed and conducted to reflect the increasingly extreme weather-related challenges faced by water utilities as the global climate changes. The first event was based on an extreme flood scenario. The second scenario involved a combination of weather events, including a wild forest fire ('bushfire') followed by runoff due to significant rainfall. For each scenario, a panel of diverse personnel from water utilities and relevant agencies (e.g. health departments) formed a hypothetical water utility and associated regulatory body to manage water quality following the simulated extreme weather event. A larger audience participated by asking questions and contributing key insights. Participants were confronted with unanticipated developments as the simulated scenarios unfolded, introduced by a facilitator. Participants were presented with information that may have challenged their conventional experiences regarding operational procedures in order to identify limitations in current procedures, assumptions, and readily available information. The process worked toward the identification of a list of specific key lessons for each event. At the conclusion of each simulation a facilitated discussion was used to establish key lessons of value to water utilities in preparing them for similar future extreme events. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Individual differences in the use of the response scale determine valuations of hypothetical health states: an empirical study

    Directory of Open Access Journals (Sweden)

    Meerding Willem-Jan

    2007-04-01

    Full Text Available Abstract Background The effects of socio-demographic characteristics of the respondent, including age, on valuation scores of hypothetical health states remain inconclusive. Therefore, we analyzed data from a study designed to discriminate between the effects of respondents' age and time preference on valuations of health states to gain insight in the contribution of individual response patterns to the variance in valuation scores. Methods A total of 212 respondents from three age groups valued the same six hypothetical health states using three different methods: a Visual Analogue Scale (VAS and two variants of the Time trade-off (TTO. Analyses included a generalizability study, principal components analysis, and cluster analysis. Results Valuation scores differed significantly, but not systematically, between valuation methods. A total of 36.8% of variance was explained by health states, 1.6% by the elicitation method, and 0.2% by age group. Individual differences in the use of the response scales (e.g. a tendency to give either high or low TTO scores, or a high or low scoring tendency on the VAS were the main source of remaining variance. These response patterns were not related to age or other identifiable respondent characteristics. Conclusion Individual response patterns in this study were more important determinants of TTO or VAS valuations of health states than age or other respondent characteristics measured. Further valuation research should focus on explaining individual response patterns as a possible key to understanding the determinants of health state valuations.

  2. Combined effects of projected sea level rise, storm surge, and peak river flows on water levels in the Skagit Floodplain

    Science.gov (United States)

    Hamman, Josheph J; Hamlet, Alan F.; Fuller, Roger; Grossman, Eric

    2016-01-01

    Current understanding of the combined effects of sea level rise (SLR), storm surge, and changes in river flooding on near-coastal environments is very limited. This project uses a suite of numerical models to examine the combined effects of projected future climate change on flooding in the Skagit floodplain and estuary. Statistically and dynamically downscaled global climate model scenarios from the ECHAM-5 GCM were used as the climate forcings. Unregulated daily river flows were simulated using the VIC hydrology model, and regulated river flows were simulated using the SkagitSim reservoir operations model. Daily tidal anomalies (TA) were calculated using a regression approach based on ENSO and atmospheric pressure forcing simulated by the WRF regional climate model. A 2-D hydrodynamic model was used to estimate water surface elevations in the Skagit floodplain using resampled hourly hydrographs keyed to regulated daily flood flows produced by the reservoir simulation model, and tide predictions adjusted for SLR and TA. Combining peak annual TA with projected sea level rise, the historical (1970–1999) 100-yr peak high water level is exceeded essentially every year by the 2050s. The combination of projected sea level rise and larger floods by the 2080s yields both increased flood inundation area (+ 74%), and increased average water depth (+ 25 cm) in the Skagit floodplain during a 100-year flood. Adding sea level rise to the historical FEMA 100-year flood resulted in a 35% increase in inundation area by the 2040's, compared to a 57% increase when both SLR and projected changes in river flow were combined.

  3. ASSESSING PEAK AEROBIC CAPACITY IN DUTCH LAW ENFORCEMENT OFFICERS

    NARCIS (Netherlands)

    Wittink, Harriet; Takken, Tim; de Groot, Janke; Reneman, Michiel; Peters, Roelof; Vanhees, Luc

    2015-01-01

    Objectives: To cross-validate the existing peak rate of oxygen consumption (VO2peak) prediction equations in Dutch law enforcement officers and to determine whether these prediction equations can be used to predict VO2peak for groups and in a single individual. A further objective was to report norm

  4. Peak-power-point monitor for solar panel

    Science.gov (United States)

    Schloss, A. I.

    1972-01-01

    Attempt was made to determine solar cell panel peak power capability without disrupting power flow from panel. Separate solar cell strings were switched from panel circuits, and increasingly larger loads were added rapidly until peak power points were transversed. String wattage output was recorded and all stored string measurements summed together indicate peak power point in panel.

  5. Bankfull characteristics of Ohio streams and their relation to peak streamflows

    Science.gov (United States)

    Sherwood, James M.; Huitger, Carrie A.

    2005-01-01

    statistical techniques. The logarithms of the annual peak discharges for the 40 gaged study sites were fit by a Pearson Type III frequency distribution to develop flood-peak discharges associated with recurrence intervals of 2, 5, 10, 25, 50, and 100 years. The peak-frequency data were related to geomorphic, basin, and climatic variables by multiple-regression analysis. Simple-regression equations were developed to estimate 2-, 5-, 10-, 25-, 50-, and 100-year flood-peak discharges of rural, unregulated streams in Ohio from bankfull channel cross-sectional area. The average standard errors of prediction are 31.6, 32.6, 35.9, 41.5, 46.2, and 51.2 percent, respectively. The study and methods developed are intended to improve understanding of the relations between geomorphic, basin, and flood characteristics of streams in Ohio and to aid in the design of hydraulic structures, such as culverts and bridges, where stability of the stream and structure is an important element of the design criteria. The study was done in cooperation with the Ohio Department of Transportation and the U.S. Department of Transportation, Federal Highway Administration.

  6. Hydrogeology, ground-water quality, and the possible effects of a hypothetical radioactive water spill, Plainsboro Township, New Jersey

    Science.gov (United States)

    Lewis, J.C.; Spitz, F.J.

    1987-01-01

    Princeton University, under contract to the Department of Energy , maintains a Tokamak fusion test reactor in New Jersey. The U.S. Geological Survey investigated groundwater flow and estimated the effects of a hypothetical spill of radioactive water at the site on the local groundwater system. The study included test drilling; aquifer testing; measurement of water levels, infiltration capacity, and stream discharge; and a simulation of the hypothetical spill. The Triassic Stockton Formation-a water supply aquifer composed primarily of jointed siltstone and sandstone-underlies the site. The aquifer is confined by overlying weathered bedrock and underlying unjointed rock. Weathered bedrock is overlain by unconsolidated, partially saturated material which ranges from 6 to 39 ft in thickness. Groundwater recharge is by lateral flow into the study area, stream leakage, and precipitation. Discharge is by pumpage, evapotranspiration, stream inflow, and lateral flow out of the study area. Transmissivity of the aquifer is about 1,740 sq ft/day, and the storage coefficient is about 0.0002. The average linear velocity of groundwater at the site ranges from 100 to 270 ft/yr depending on location and time of year. The velocity over a large part of the site is controlled by on-site pumpage. Groundwater samples were collected and analyzed for common ions, trace metals, and tritium. The analyses reported no concentrations of common ions or trace metals which exceeded the criteria for drinking water standards recommended by the EPA, except for some instances of moderately high concentrations of iron and manganese. Iron and manganese are common in groundwater and surface water in the area and are not indicative of an on-site source of contamination. Tritium concentrations in the collected samples were also considered representative of background levels and were well below the maximum concentration permitted by the EPA. The fate of spilled radioactive water after a hypothetical

  7. Economic and safety analysis of unconventional peak regulation on power unit of peak shifting start-stop

    Science.gov (United States)

    Cao, X.; Zhao, J. F.; Duan, X. Q.; Jin, Y. A.

    2017-01-01

    Tthe capacity difference of peak regulation between the power gird and the actual demand has become a serious problem considering the growth in the difference between electricity supply and demand. Therefore, peak regulation of power grid needs to be deeply studied. Unconventional peak regulation on unit of peak shifting start-stop is a way that can broaden the range of power regulation, as well as benefit safe operation of the power grid. However, it requires frequent and fast unit start-stop, complex operation, and more staff labor. By carrying out unconventional thermal power unit load test, the start-stop mode of peak auxiliary equipment is studied in this paper, indicating that it has a positive effect on safety and economic of load-peaking operation. The best working conditions of the peak units is found by analysing consumption cost, safety specifications, and life lost of the start-stop peak regulation mode.

  8. The formation of peak rings in large impact craters.

    Science.gov (United States)

    Morgan, Joanna V; Gulick, Sean P S; Bralower, Timothy; Chenot, Elise; Christeson, Gail; Claeys, Philippe; Cockell, Charles; Collins, Gareth S; Coolen, Marco J L; Ferrière, Ludovic; Gebhardt, Catalina; Goto, Kazuhisa; Jones, Heather; Kring, David A; Le Ber, Erwan; Lofi, Johanna; Long, Xiao; Lowery, Christopher; Mellett, Claire; Ocampo-Torres, Rubén; Osinski, Gordon R; Perez-Cruz, Ligia; Pickersgill, Annemarie; Poelchau, Michael; Rae, Auriol; Rasmussen, Cornelia; Rebolledo-Vieyra, Mario; Riller, Ulrich; Sato, Honami; Schmitt, Douglas R; Smit, Jan; Tikoo, Sonia; Tomioka, Naotaka; Urrutia-Fucugauchi, Jaime; Whalen, Michael; Wittmann, Axel; Yamaguchi, Kosei E; Zylberman, William

    2016-11-18

    Large impacts provide a mechanism for resurfacing planets through mixing near-surface rocks with deeper material. Central peaks are formed from the dynamic uplift of rocks during crater formation. As crater size increases, central peaks transition to peak rings. Without samples, debate surrounds the mechanics of peak-ring formation and their depth of origin. Chicxulub is the only known impact structure on Earth with an unequivocal peak ring, but it is buried and only accessible through drilling. Expedition 364 sampled the Chicxulub peak ring, which we found was formed from uplifted, fractured, shocked, felsic basement rocks. The peak-ring rocks are cross-cut by dikes and shear zones and have an unusually low density and seismic velocity. Large impacts therefore generate vertical fluxes and increase porosity in planetary crust. Copyright © 2016, American Association for the Advancement of Science.

  9. The formation of peak rings in large impact craters

    Science.gov (United States)

    Morgan, Joanna V.; Gulick, Sean P. S.; Bralower, Timothy; Chenot, Elise; Christeson, Gail; Claeys, Philippe; Cockell, Charles; Collins, Gareth S.; Coolen, Marco J. L.; Ferrière, Ludovic; Gebhardt, Catalina; Goto, Kazuhisa; Jones, Heather; Kring, David A.; Le Ber, Erwan; Lofi, Johanna; Long, Xiao; Lowery, Christopher; Mellett, Claire; Ocampo-Torres, Rubén; Osinski, Gordon R.; Perez-Cruz, Ligia; Pickersgill, Annemarie; Poelchau, Michael; Rae, Auriol; Rasmussen, Cornelia; Rebolledo-Vieyra, Mario; Riller, Ulrich; Sato, Honami; Schmitt, Douglas R.; Smit, Jan; Tikoo, Sonia; Tomioka, Naotaka; Urrutia-Fucugauchi, Jaime; Whalen, Michael; Wittmann, Axel; Yamaguchi, Kosei E.; Zylberman, William

    2016-11-01

    Large impacts provide a mechanism for resurfacing planets through mixing near-surface rocks with deeper material. Central peaks are formed from the dynamic uplift of rocks during crater formation. As crater size increases, central peaks transition to peak rings. Without samples, debate surrounds the mechanics of peak-ring formation and their depth of origin. Chicxulub is the only known impact structure on Earth with an unequivocal peak ring, but it is buried and only accessible through drilling. Expedition 364 sampled the Chicxulub peak ring, which we found was formed from uplifted, fractured, shocked, felsic basement rocks. The peak-ring rocks are cross-cut by dikes and shear zones and have an unusually low density and seismic velocity. Large impacts therefore generate vertical fluxes and increase porosity in planetary crust.

  10. Conserved hypothetical protein Rv1977 in Mycobacterium tuberculosis strains contains sequence polymorphisms and might be involved in ongoing immune evasion.

    Science.gov (United States)

    Jiang, Yi; Liu, Haican; Wang, Xuezhi; Li, Guilian; Qiu, Yan; Dou, Xiangfeng; Wan, Kanglin

    2015-01-01

    Host immune pressure and associated parasite immune evasion are key features of host-pathogen co-evolution. A previous study showed that human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved and thus it was deduced that M. tuberculosis lacks antigenic variation and immune evasion. Here, we selected 151 clinical Mycobacterium tuberculosis isolates from China, amplified gene encoding Rv1977 and compared the sequences. The results showed that Rv1977, a conserved hypothetical protein, is not conserved in M. tuberculosis strains and there are polymorphisms existed in the protein. Some mutations, especially one frameshift mutation, occurred in the antigen Rv1977, which is uncommon in M.tb strains and may lead to the protein function altering. Mutations and deletion in the gene all affect one of three T cell epitopes and the changed T cell epitope contained more than one variable position, which may suggest ongoing immune evasion.

  11. In silico Sequence Analysis, Homology Modeling and Function Annotation of Ocimum basilicum Hypothetical Protein G1CT28_OCIBA

    Directory of Open Access Journals (Sweden)

    Sobia Idrees

    2012-07-01

    Full Text Available Ocimum basilicum is commonly known as sweet basil and belongs to the Lamiaceae Family. Ocimum basilicum has great therapeutic benefits and can be used for lowering blood pressure, as an antispasmodic as well as cleansing the blood. In the present study, subcellular localization prediction suggested that it is a cytoplasmic protein. We predicted the 3D structure of protein using homology modeling as 3D structure prediction approach. 3D structure of the protein was determined using Protein Structure Prediction Server (PS2 selecting MODELLER as 3D structure prediction method. Quality analysis of the model indicated that it is a reliable model. Furthermore, it was discovered that Ocimum basilicum hypothetical protein G1CT28_OCIBA is involved in two biological processes, oxidation reduction and metabolic process and the biochemical function of the protein is acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, catalytic activity and oxidoreductase.

  12. Structural properties of hypothetical CeBa2Cu3O7 compound from LSDA+DMFT calculations

    Directory of Open Access Journals (Sweden)

    Łuszczek Maciej

    2016-09-01

    Full Text Available The hypothetical stoichiometric CeBa2Cu3O7 (Ce123 compound, which has not been synthesized as a single phase yet, was studied by the density functional theory (DFT. We utilized a method which merges the local spin density approximation (LSDA with the dynamical mean-field theory (DMFT to account for the electronic correlations. The LSDA+DMFT calculations were performed in the high-temperature range. The particular emphasis was put on the pressure-induced changes in the electronic band structure related to strongly correlated 4f states. The computational results indicate the occurrence of a large negative volumetric thermal expansion coefficient near T = 500 K and a trace of a low-volume isostructural metastable state at high temperatures.

  13. Investigating a Hypothetical Semiconductor Laser Bar with a Damaged Single Emitter Using a Laser Diode Simulation/Emulation Tool

    Directory of Open Access Journals (Sweden)

    C.K. Amuzuvi

    2014-02-01

    Full Text Available This study demonstrates the use of Barlase, a semiconductor laser diode emulation tool, to emulate the by-emitter degradation of high power semiconductor laser diodes.Barlase is software that uses a LabView control interface. In this study, a hypothetical laser diode bar (multiple emitters was used to investigate a damaged single emitter randomly located in the bar and its behavior analyzed within the bar. It should however, be noted that, this scenario is valid for devices at the start of the aging process only. When all other relevant effects that affect the performance of laser diodes bars are allowed to interact over time, high levels of defects can also play important role in the degradation process. The results of this simulation scenario show the successful implementation of Barlase in the by-emitter analysis of laser diodes.

  14. Cues of High and Low Body Weight Negatively Influence Adults' Perceptions and Ratings in the Hypothetical Adoption Paradigm

    Directory of Open Access Journals (Sweden)

    Anthony A. Volk

    2006-01-01

    Full Text Available Infant and child facial cues influence perceptions and ratings in the Hypothetical Adoption Paradigm as well as actual parental care. A previous study demonstrated that infant and child facial cues of low body weight negatively influenced adults' ratings. The current study sought to replicate and expand on those results by presenting adults with normal faces as well as faces that were digitally altered to display high or low body weight. Cues of abnormal body weight significantly, and negatively, influenced adults’ ratings of adoption preference, health, and cuteness. Effect sizes were larger for cues of high body weight. Thus, infant and child facial cues of abnormal body weight may represent a relative risk factor to the quality of adult care obtained by children with abnormal body weight.

  15. Assessment in marine environment for a hypothetic nuclear accident based on the database of tidal harmonic constants.

    Science.gov (United States)

    Min, Byung-Il; Periáñez, Raúl; Park, Kihyun; Kim, In-Gyu; Suh, Kyung-Suk

    2014-10-15

    The eleven nuclear power plants in operation, under construction and a well-planned plant in the east coast of China generally use seawater for reactor cooling. In this study, an oceanic dispersion assessment system based on a database of tidal harmonic constants is developed. This system can calculate the tidal current without a large computational cost, and it is possible to calculate real-time predictions of pollutant dispersions in the ocean. Calculated amplitudes and phases have maximum errors of 10% and 20% with observations, respectively. A number of hypothetical simulations were performed according to varying of the release starting time and duration of pollutant for the six nuclear sites in China. The developed system requires a computational time of one hour for one month of real-time forecasting in Linux OS. Thus, it can use to evaluate rapidly the dispersion characteristics of the pollutants released into the sea from a nuclear accident.

  16. Automatic Peak Selection by a Benjamini-Hochberg-Based Algorithm

    KAUST Repository

    Abbas, Ahmed

    2013-01-07

    A common issue in bioinformatics is that computational methods often generate a large number of predictions sorted according to certain confidence scores. A key problem is then determining how many predictions must be selected to include most of the true predictions while maintaining reasonably high precision. In nuclear magnetic resonance (NMR)-based protein structure determination, for instance, computational peak picking methods are becoming more and more common, although expert-knowledge remains the method of choice to determine how many peaks among thousands of candidate peaks should be taken into consideration to capture the true peaks. Here, we propose a Benjamini-Hochberg (B-H)-based approach that automatically selects the number of peaks. We formulate the peak selection problem as a multiple testing problem. Given a candidate peak list sorted by either volumes or intensities, we first convert the peaks into p-values and then apply the B-H-based algorithm to automatically select the number of peaks. The proposed approach is tested on the state-of-the-art peak picking methods, including WaVPeak [1] and PICKY [2]. Compared with the traditional fixed number-based approach, our approach returns significantly more true peaks. For instance, by combining WaVPeak or PICKY with the proposed method, the missing peak rates are on average reduced by 20% and 26%, respectively, in a benchmark set of 32 spectra extracted from eight proteins. The consensus of the B-H-selected peaks from both WaVPeak and PICKY achieves 88% recall and 83% precision, which significantly outperforms each individual method and the consensus method without using the B-H algorithm. The proposed method can be used as a standard procedure for any peak picking method and straightforwardly applied to some other prediction selection problems in bioinformatics. The source code, documentation and example data of the proposed method is available at http://sfb.kaust.edu.sa/pages/software.aspx. © 2013

  17. Automatic peak selection by a Benjamini-Hochberg-based algorithm.

    Directory of Open Access Journals (Sweden)

    Ahmed Abbas

    Full Text Available A common issue in bioinformatics is that computational methods often generate a large number of predictions sorted according to certain confidence scores. A key problem is then determining how many predictions must be selected to include most of the true predictions while maintaining reasonably high precision. In nuclear magnetic resonance (NMR-based protein structure determination, for instance, computational peak picking methods are becoming more and more common, although expert-knowledge remains the method of choice to determine how many peaks among thousands of candidate peaks should be taken into consideration to capture the true peaks. Here, we propose a Benjamini-Hochberg (B-H-based approach that automatically selects the number of peaks. We formulate the peak selection problem as a multiple testing problem. Given a candidate peak list sorted by either volumes or intensities, we first convert the peaks into [Formula: see text]-values and then apply the B-H-based algorithm to automatically select the number of peaks. The proposed approach is tested on the state-of-the-art peak picking methods, including WaVPeak [1] and PICKY [2]. Compared with the traditional fixed number-based approach, our approach returns significantly more true peaks. For instance, by combining WaVPeak or PICKY with the proposed method, the missing peak rates are on average reduced by 20% and 26%, respectively, in a benchmark set of 32 spectra extracted from eight proteins. The consensus of the B-H-selected peaks from both WaVPeak and PICKY achieves 88% recall and 83% precision, which significantly outperforms each individual method and the consensus method without using the B-H algorithm. The proposed method can be used as a standard procedure for any peak picking method and straightforwardly applied to some other prediction selection problems in bioinformatics. The source code, documentation and example data of the proposed method is available at http://sfb.kaust.edu.sa/pages/software.aspx.

  18. In silico identification and characterization of a hypothetical protein of Mycobacterium tuberculosis EAI5 as a potential virulent factor

    Science.gov (United States)

    Gupta, Debdoot; Banerjee, Samiddha; Pailan, Santanu; Saha, Pradipta

    2016-01-01

    Tuberculosis, a life threatening disease caused by different strains of Mycobacterium tuberculosis is creating an alarming condition due to the emergence of increasing multi drug resistance (MDR) trait. In this study, in silico approach was used for the identification of a conserved novel virulent factor in Mycobacterium tuberculosis EAI5 (Accession no.CP006578) which can also act as potential therapeutic target. Systematic comparative search of genes that are common to strain EAI5 and other human pathogenic strains of M. tuberculosis enlisted 408 genes. These were absent in the non-pathogenic Mycobacterium smegmatis MC2155 and in the human genome. Among those genes, only the protein coding hypothetical genes (97 out of 408) and their corresponding products were selected for further exploration. Of these, 11 proteins were found to have notable conserved domains, of which one hypothetical protein (NCBI Acc No. AGQ35418.1) was selected for further in silico exploration which was found to have two functional domains, one having phosphatidylinositol specific phospholipase C (PI-PLC) activity while the other short domain with weak lectin binding activity. As PI-PLC contributes virulence property in some pathogenic bacteria with a broad range of activities, different bioinformatic tools were used to explore its physicochemical and other important properties which indicated its secretary nature. This PI-PLC was previously not reported as drug/vaccine target to the best of our knowledge. Its predicted 3D structure can be explored for development of inhibitor for novel therapeutic strategies against MDR-TB.

  19. Pediatrician’s cough and cold medication prescription for hypothetical cases – A cross-sectional multi-centric study

    Directory of Open Access Journals (Sweden)

    Sudha Chandelia

    2016-03-01

    Full Text Available Background: Concerns over inappropriate use of cough and cold medication (CCM in children have been raised. In addition to being ineffective, these are now considered toxic for young children. Despite this fact studies from some regions have shown high use of these medications by physicians. However data on pediatricians and from India are negligible. Aim: To study the burden and patterns of cough and cold medications use by pediatricians for hypothetical cases. Methods: In this cross-sectional study; 172 pediatricians of various hospitals of Delhi and Haryana were enrolled from February 15 to March 15, 2012. They were contacted personally by authors and asked to write their prescriptions for two hypothetical case scenarios [having cough and cold] of two different age groups; (1 less than 2 years and (2 2–5 years. We made two categories as recommendations exist for children less than 2 years while recommendations for the second category are underway. Results were summarized as percentages, counts and; presented in tables and figures. Chi square test was used to establish association between categorical variables of subgroups. Results: Response rate was 93%. The most used CCM was antihistaminics (82% and systemic sympathomimetics (48%. The use of CCM was significantly less in teaching hospitals as compared to non-teaching (77% vs. 95%; p-value – 0.025. However there was no statistical difference in the practice of post graduates and more senior pediatricians (p value-0.895. No difference in CCM use in two age groups {(82% (less than 2 years vs. 85% (2–5 years; p-value – 0.531} was observed. Conclusion: Overall use of CCM is still high irrespective of patient age, pediatrician’s seniority or hospital setting. Efforts should be made to create awareness among the pediatricians regarding cautious use of these medications.

  20. Does message framing predict willingness to participate in a hypothetical HIV vaccine trial: an application of Prospect Theory.

    Science.gov (United States)

    Evangeli, Michael; Kafaar, Zuhayr; Kagee, Ashraf; Swartz, Leslie; Bullemor-Day, Philippa

    2013-01-01

    It is vital that enough participants are willing to participate in clinical trials to test HIV vaccines adequately. It is, therefore, necessary to explore what affects peoples' willingness to participate (WTP) in such trials. Studies have only examined individual factors associated with WTP and not the effect of messages about trial participation on potential participants (e.g., whether losses or gains are emphasized, or whether the outcome is certain or uncertain). This study explores whether the effects of message framing on WTP in a hypothetical HIV vaccine trial are consistent with Prospect Theory. This theory suggests that people are fundamentally risk averse and that (1) under conditions of low risk and high certainty, gain-framed messages will be influential (2) under conditions of high risk and low certainty, loss-framed messages will be influential. This cross-sectional study recruited 283 HIV-negative students from a South African university who were given a questionnaire that contained matched certain gain-framed, certain loss-framed, uncertain gain-framed, and uncertain loss-framed statements based on common barriers and facilitators of WTP. Participants were asked to rate how likely each statement was to result in their participation in a hypothetical preventative HIV vaccine trial. Consistent with Prospect Theory predictions, for certain outcomes, gain-framed messages were more likely to result in WTP than loss-framed messages. Inconsistent with predictions, loss-framed message were not more likely to be related to WTP for uncertain outcomes than gain-framed messages. Older students were less likely to express their WTP across the different message frames. Recruitment for HIV vaccine trials should pay attention to how messages about the trial are presented to potential participants.

  1. Response to Hypothetical Social Scenarios in Individuals with Traumatic Brain Injury Who Present Inappropriate Social Behavior: A Preliminary Report

    Directory of Open Access Journals (Sweden)

    Michel Ouellette

    2013-01-01

    Full Text Available Background: Very little research thus far has examined the decision making that underlies inappropriate social behavior (ISB post-TBI (traumatic brain injury. Objectives: To verify the usefulness of a new instrument, the Social Responding Task, for investigating whether, in social decision making, individuals with TBI, who present inappropriate social behavior (ISB, have difficulty anticipating their own feelings of embarrassment and others’ angry reactions following an ISB. Methods: Seven subjects with TBI presenting with inappropriate social behavior (TBI-ISB, 10 presenting with appropriate social behavior (TBI-ASB, and 15 healthy controls were given 12 hypothetical scenarios three times, each time ending with a different behavioral response. Subjects were asked to gauge the likelihood of their displaying the behavior in that situation (part A and of it being followed by an angry reaction from the other or by feelings of embarrassment in themselves (part B. Results: TBI-ISB subjects scored higher than TBI-ASB and healthy controls on a scale of likelihood of displaying an ISB. Results regarding expectations of angry reactions from others and feelings of embarrassment after an ISB were similar among groups. Negative correlations between endorsement of an inappropriate behavior and anticipation of negative emotional consequences were significant for both TBI-ASB and control subjects, but not for TBI-ISB subjects. Conclusions: Results suggest that the TBI-ISB participants were likely to endorse an ISB despite being able to anticipate a negative emotional response in themselves or others, suggesting that there were other explanations for their poor behavior. A self-reported likely response to hypothetical social scenarios can be a useful approach for studying the neurocognitive processes behind the poor choices of individuals with TBI-ISB, but the task needs further validation studies. A comprehensive discussion follows on the underlying

  2. [100 years of studying poliomyelitis virus and nonpoliomyelitis enteroviruses].

    Science.gov (United States)

    Lashkevich, V A

    2008-01-01

    M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitis, Russian Academy of Medical Sciences, Moscow The paper deals with the history of discovery of poliomyelitis virus by K. Landsteiner and E. Popper in 1908, the identification of three immunological types of the virus in 1949, the discovery of viral multiplication in the cultures of non-nerve cells with a cytopathogenic effect by A. Anders in 1949, the development of new diagnostic techniques, the design of inactivated poliovirus vaccine by D. Salk in 1953 and its live vaccine by A. Sabin in 1957. The advantages and disadvantages of these vaccines and the prospects for further poliomyelitis control are discussed. The characteristics and role of nonpoliomyelitis enteroviruses are considered. The most important scientific discoveries made in the study of enteroviruses are noted.

  3. Celebrating 100 Years of Flight: Testing Wing Designs in Aircraft

    Science.gov (United States)

    Pugalee, David K.; Nusinov, Chuck; Giersch, Chris; Royster, David; Pinelli, Thomas E.

    2005-01-01

    This article describes an investigation involving several designs of airplane wings in trial flight simulations based on a NASA CONNECT program. Students' experiences with data collection and interpretation are highlighted. (Contains 5 figures.)

  4. Mário de Sá-Carneiro, 100 years later

    Directory of Open Access Journals (Sweden)

    Paula Cristina Costa

    2016-12-01

    Full Text Available http://dx.doi.org/10.5007/2175-7917.2016v21n2p112 Mário de Sá-Carneiro’s work is still current even hundred years after his death: the modernity of his style is not limited to the modernist fashions of the time, but remains contemporary of today. This work has a large thematic coherence. Throughout his poetry, prose and drama, is repeated anew the theme of Myself/Other, the desire to achieve absolute perfection, such as Icarus, and the failure of this fulfillment. In texts like the well known «Quasi» and «7» poems as well as in the «A Confissão de Lúcio» novel, it is clearly present this wish for the merge between Myself and the Other and the impossibility of achieving it. Mário de Sá-Carneiro was, together with Fernando Pessoa, one of the founders of the Portuguese Modernism and one of the directors of «Orpheu» magazine. Both poets created several important isms for the Portuguese Modermism: paulismo, interseccionismo, sensacionismo. Nevertheless they kept themselves loyal to their own styles.

  5. I. P. PAVLOV: 100 YEARS OF RESERACH ON ASSOCIATIVE LEARNING

    Directory of Open Access Journals (Sweden)

    GERMÁN GUTIÉRREZ

    2005-07-01

    Full Text Available A biographical summary of Ivan Pavlov is presented, emphasizing his academic formation and achievements, and hiscontributions to general science and psychology. His main findings on associative learning are described and three areasof current development in this area are discussed: the study of behavioral mechanisms, the study of neurobiologicalmechanisms and the functional role of learning.

  6. 100 Years of Attempts to Transform Physics Education

    Science.gov (United States)

    Otero, Valerie K.; Meltzer, David E.

    2016-12-01

    As far back as the late 1800s, U.S. physics teachers expressed many of the same ideas about physics education reform that are advocated today. However, several popular reform efforts eventually failed to have wide impact, despite strong and enthusiastic support within the physics education community. Broad-scale implementation of improved instructional models today may be just as elusive as it has been in the past, and for similar reasons. Although excellent instructional models exist and have been available for decades, effective and scalable plans for transforming practice on a national basis have yet to be developed and implemented. Present-day teachers, education researchers, and policy makers can find much to learn from past efforts, both in their successes and their failures. To this end, we present a brief outline of some key ideas in U.S. physics education during the past 130 years. We address three core questions that are prominent in the literature: (a) Why and how should physics be taught? (b) What physics should be taught? (c) To whom should physics be taught? Related issues include the role of the laboratory and attempts to make physics relevant to everyday life. We provide here only a brief summary of the issues and debates found in primary-source literature; an extensive collection of historical resources on physics education is available at https://sites.google.com/site/physicseducationhistory/home.

  7. The death of Florence Nightingale: BJN 100 years ago.

    Science.gov (United States)

    Castledine, Sir George

    This August marks the centenary of the death of Florence Nightingale, who died at 2 o'clock on Saturday 13 August 1910 at her home, 10 South Street, Park Lane, London. The following are some snippets which appeared in the BJN of the 20 and 27 August 1910. It was not until the announcement of her death in the morning papers of Monday 15 August that the country heard about Nightingale's death. In her last hours she was attended by Sir Thomas Barlow and two nurses from the Nursing Sisters' Institution, Devonshire Square, founded by Mrs Elizabeth Fry in 1840.

  8. 100 years after the Marsica earthquake: contribute of outreach activities

    Science.gov (United States)

    D'Addezio, Giuliana; Giordani, Azzurra; Valle, Veronica; Riposati, Daniela

    2015-04-01

    Many outreach events have been proposed by the scientific community to celebrate the Centenary of the January 13, 1915 earthquake, that devastated the Marsica territory, located in Central Apennines. The Laboratorio Divulgazione Scientifica e Attività Museali of the Istituto Nazionale di Geofisica e Vulcanologia (INGV's Laboratory for Outreach and Museum Activities) in Rome, has realised an interactive exhibition in the Castello Piccolomini, Celano (AQ), to retrace the many aspects of the earthquake disaster, in a region such as Abruzzo affected by several destructive earthquakes during its history. The initiatives represent an ideal opportunity for the development of new programs of communication and training on seismic risk and to spread the culture of prevention. The INGV is accredited with the Servizio Civile Nazionale (National Civic Service) and volunteers are involved in the project "Science and Outreach: a comprehensive approach to the divulgation of knowledge of Earth Sciences" starting in 2014. In this contest, volunteers had the opportunity to fully contribute to the exhibition, in particular, promoting and realising two panels concerning the social and environmental consequences of the Marsica earthquake. Describing the serious consequences of the earthquake, we may raise awareness about natural hazards and about the only effective action for earthquake defense: building with anti seismic criteria. After studies and researches conducted in libraries and via web, two themes have been developped: the serious problem of orphans and the difficult reconstruction. Heavy snowfalls and the presence of wolves coming from the high and wild surrounding mountains complicated the scenario and decelerated the rescue of the affected populations. It is important to underline that the earthquake was not the only devastating event in the country in 1915; another drammatic event was, in fact, the First World War. Whole families died and the still alive infants and children were sent to Rome in hospitals and in other suitable structures. Many stories of poor orphans are known but we decided to outlines stories that besides the dramma had an happy ending. To understand the hugeness of the tragedy, we may consider that the number of towns and villages completely destroyed by the earthquake was more than fifty. The reconstruction was very difficult and slow also because of the war, and involved the relocation of settlements in different places. The first shelters to be reconstructed were those for survivors: very small shacks built with anti seismic criteria. They are still on the territory, to be a symbol of the reconstruction and a remined evidence of the earthquake.

  9. Evolutionary Lightsailing Missions for the 100-Year Starship

    Science.gov (United States)

    Friedman, L.; Garber, D.; Heinsheimer, T.

    Incremental milestones towards interstellar flight can be achieved in this century by building on first steps with lightsailing, the only known technology that might someday take us to the stars. That this is now possible is enabled by achievements of first solar sail flights, the use of nano-technology for miniaturization of spacecraft, advances in information processing and the decoding of our genomes into transportable form. This paper quantifies a series of robotic steps through and beyond the solar system that are practical and would stimulate the development of new technologies in guidance, navigation, materials, communication, sensors, information processing etc. while exploring ever-more distant, exciting space objectives at distances impractical for classical rocket-based technologies. There robotic steps may be considered as precursors to human interstellar flight, but they may also be considered as evolutionary steps that provide for a different future: One of virtual human interstellar flight that may bypass the ideas of the past (big rockets launching heavy people) in favour of those of the future ­ networking amongst the stars with information, and the physical transport of digital and biological genomes.

  10. SA stands on the shoulders of 100 years of innovation

    CSIR Research Space (South Africa)

    Wall, K

    2010-05-01

    Full Text Available Aircraft and the motor car, with improved roads, have revolutionised inter-city travel; the internet has revolutionised how learners prepare assignments; computers have revolutionised data sorting and analysis, and so on. This newspaper article...

  11. Martin Gardner: 100 Years of the Magic of Physics

    Science.gov (United States)

    Gillaspy, John D.

    2014-01-01

    2014 marks the 100th anniversary of the birth of Martin Gardner, a man whose writings helped inspire generations of young students to pursue a career in physics and mathematics. From his first to his last, and many in between, Gardner's publications often combined magic and science. A recurring theme was the clever use of physical principles…

  12. [100 years of surgery in the Kosevo Hospital in Sarajevo].

    Science.gov (United States)

    Durić, O

    1994-01-01

    The surgery Department of the Regional Hospital was opened on 1st July, 1894 in Sarajevo, what meant the beginnings of European surgery school influence here. The School was in the second half of its activity, better known as "century of surgery". The building, fittings, equipment and staff continued their work here coping the Viennese school achievements. It was headed by the prominent European surgeon, primarius Dr Josef Preindisberger, first assistant to the great personality Dr. Billroth. In the way this institution became a referral centre for two other hospitals in Sarajevo: the Vakuf's and the Military Hospital, but for some 17 more in BH, which were built in the course of ten years. Because of the therapeutic success in the domain of the general surgery and diseases of the eye and according the annual reports, the first 50 beds became insufficient for all those who wanted the treatment. So, the Department was enlarged, in 1905 a new regional Hospital was planned, to act as clinics. The World War 1 stopped the plans. During the period of Kingdom of Yugoslavia, destroyed by war, the Surgery Department continued its work with the doctors educated to continue the work on the pre war level. As a broad pathology basis, but the need of space that time chief surgeon. Primarius Milivoje Kostić worked out in details the former plan of the new hospital building up with a base for clinics. It was accepted as a ten years project, which, to the regrets, did not come to existence to the World War 2.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. Sunspot Cycle 24: Smallest Cycle in 100 Years?

    Science.gov (United States)

    2005-01-11

    and H. B. Hathaway, D. H., R. M. Wilson, and E. J. Reichmann (1994), The shape of Snodgrass (1988), The extended solar activity cycle, Nature, 333...748, the sunspot cycle, Sol. Phys., 151, 177. doi:10.1038/333748a0. Hathaway, D. H., R. M. Wilson, and E. J. Reichmann (2002), Group sun- spot numbers

  14. History of the Shaped Charge Effect: The First 100 Years

    Science.gov (United States)

    1990-03-22

    transferred, inasmuch as 10 Part 1 both originators of the effect were in proximiy - southern Gernmany and Switzerland border each other. Dr. Mohaupt’s...Mistel ( Mistletoe ) referred to the parasitic mounting of the top aircraft on the host aircraft. In the tactical version, the bomber’s nose was replaced...16) in the patents (Ref. 32) issued in France in 1940 and in Australia in 1941, wherein the inventors (Mohaupt and his two associates) had claimed the

  15. Engineering and malaria control: learning from the past 100 years

    DEFF Research Database (Denmark)

    Konradsen, Flemming; van der Hoek, Wim; Amerasinghe, Felix P

    2004-01-01

    Traditionally, engineering and environment-based interventions have contributed to the prevention of malaria in Asia. However, with the introduction of DDT and other potent insecticides, chemical control became the dominating strategy. The renewed interest in environmental-management-based approa......Traditionally, engineering and environment-based interventions have contributed to the prevention of malaria in Asia. However, with the introduction of DDT and other potent insecticides, chemical control became the dominating strategy. The renewed interest in environmental...

  16. Huck Finn: 100 Years of Durn Fool Problems.

    Science.gov (United States)

    Stanek, Lou Willett

    1985-01-01

    Discusses the censorship of Mark Twain's "Huckleberry Finn" since it was first published in 1885. Highlights include Twain's public image, viewpoints of censors, the banning of the book and school censorship cases, and the celebration of the centennial of "Huckleberry Finn." Nine references are cited. (EJS)

  17. 100 Years of Curriculum History, Theory, and Research

    Science.gov (United States)

    Schoenfeld, Alan H.

    2016-01-01

    This article reviews a collection of papers written by the American Educational Research Association's first 50 presidents that deal specifically with curricular issues. It characterizes the ways in which curricula were conceptualized, implemented, and assessed, with an eye toward the epistemological and methodological framings that the authors…

  18. 100 years of public electricity supply in Germany

    Energy Technology Data Exchange (ETDEWEB)

    Gersdorff, B. von

    1984-05-08

    On May, 8sup(th), 1884, Emil Rathenau founded Germany's first power utility company, the Municipal Electricity Works, Berlin, the predecessor of today's Berlin Power and Light Co. (Bewag). Rathenau had recognised the significance of Thomas Alva Edison's light bulb for a broad application of electricity. Block power plants with machine outputs of 150 PS were at the beginning of their development in 1884. Today, in nuclear power plants with machine outputs of around 1300 MW, the technology of power supply has reached the ''large technology'' prophesied by Rathenau at the start of the century. With today's challenge of environment conservation the power utilities are confronted with new tasks for the future.

  19. 100 Years of Attempts to Transform Physics Education

    Science.gov (United States)

    Otero, Valerie K.; Meltzer, David E.

    2016-01-01

    As far back as the late 1800s, U.S. physics teachers expressed many of the same ideas about physics education reform that are advocated today. However, several popular reform efforts eventually failed to have wide impact, despite strong and enthusiastic support within the physics education community. Broad-scale implementation of improved…

  20. Developing Resilient Children: After 100 Years of Montessori Education

    Science.gov (United States)

    Drake, Meg

    2008-01-01

    In this millennium, educators are faced with a number of issues that Dr. Maria Montessori could not have predicted. Today, students are different from the children Dr. Montessori observed in her "Casa dei Bambini." They are influenced by technology in all its forms. Some suffer from medical problems such as complex food allergies, which wreak…

  1. 100 years of seismic research on the Moho

    DEFF Research Database (Denmark)

    Prodehl, Claus; Kennett, Brian; Artemieva, Irina

    2013-01-01

    on the Moho is primarily based on the comprehensive overview of the worldwide history of seismological studies of the Earth's crust using controlled sources from 1850 to 2005, by Prodehl and Mooney (2012). Though the art of applying explosions, so-called “artificial events”, as energy sources for studies......The detection of a seismic boundary, the “Moho”, between the outermost shell of the Earth, the Earth's crust, and the Earth's mantle by A. Mohorovičić was the consequence of increased insight into the propagation of seismic waves caused by earthquakes. This short history of seismic research...

  2. 100 YEARS OF AUDI%百年奥迪

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Since entering China in 1988, Audi has been ranked "China Auto Customer Service Satisfaction" champion and "China Auto Sales Satisfaction" champion ten times by J.D. Power, meanwhile becoming the first luxury car brand in the Chinese market to exceed one million units in sales. This success is not only due to the formidable technical background based on the idea of "Innovation through Technology,"%源于德国的奥迪汽车1988年挺进中国,二十几年内,十次摘得J.D.Power公布的"中国汽车用户服务满意度"冠军和"中国汽车销售满意度"冠军,并成为第一个中国地区累计销量超过100万辆的高档汽车品牌。奥迪在中国的成功不仅源自"突破科技、启迪未来"的技术背景,更要归功于其品牌策划与本地用户的良性互动。3月21日,"心动上海"奥迪艺术展在沪申画廊开幕。策展人顾振清生于上海,

  3. Simulation of broad-band strong ground motion for a hypothetical Mw 7.1 earthquake on the Enriquillo Fault in Haiti

    Science.gov (United States)

    Douilly, Roby; Mavroeidis, George P.; Calais, Eric

    2017-10-01

    The devastating 2010 Mw 7.0 Haiti earthquake demonstrated the need to improve mitigation and preparedness for future seismic events in the region. Previous studies have shown that the earthquake did not occur on the Enriquillo Fault, the main plate boundary fault running through the heavily populated Port-au-Prince region, but on the nearby and previously unknown transpressional Léogâne Fault. Slip on that fault has increased stresses on the segment of Enriquillo Fault to the east of Léogâne, which terminates in the ˜3-million-inhabitant capital city of Port-au-Prince. In this study, we investigate ground shaking in the vicinity of Port-au-Prince, if a hypothetical rupture similar to the 2010 Haiti earthquake occurred on that segment of the Enriquillo Fault. We use a finite element method and assumptions on regional tectonic stress to simulate the low-frequency ground motion components using dynamic rupture propagation for a 52-km-long segment. We consider eight scenarios by varying parameters such as hypocentre location, initial shear stress and fault dip. The high-frequency ground motion components are simulated using the specific barrier model in the context of the stochastic modeling approach. The broad-band ground motion synthetics are subsequently obtained by combining the low-frequency components from the dynamic rupture simulation with the high-frequency components from the stochastic simulation using matched filtering at a crossover frequency of 1 Hz. Results show that rupture on a vertical Enriquillo Fault generates larger horizontal permanent displacements in Léogâne and Port-au-Prince than rupture on a south-dipping Enriquillo Fault. The mean horizontal peak ground acceleration (PGA), computed at several sites of interest throughout Port-au-Prince, has a value of ˜0.45 g, whereas the maximum horizontal PGA in Port-au-Prince is ˜0.60 g. Even though we only consider a limited number of rupture scenarios, our results suggest more intense ground

  4. Numerical tsunami simulations in the western Pacific Ocean and East China Sea from hypothetical M 9 earthquakes along the Nankai trough

    Science.gov (United States)

    Harada, Tomoya; Satake, Kenji; Furumura, Takashi

    2017-04-01

    We carried out tsunami numerical simulations in the western Pacific Ocean and East China Sea in order to examine the behavior of massive tsunami outside Japan from the hypothetical M 9 tsunami source models along the Nankai Trough proposed by the Cabinet Office of Japanese government (2012). The distribution of MTHs (maximum tsunami heights for 24 h after the earthquakes) on the east coast of China, the east coast of the Philippine Islands, and north coast of the New Guinea Island show peaks with approximately 1.0-1.7 m,4.0-7.0 m,4.0-5.0 m, respectively. They are significantly higher than that from the 1707 Ho'ei earthquake (M 8.7), the largest earthquake along the Nankai trough in recent Japanese history. Moreover, the MTH distributions vary with the location of the huge slip(s) in the tsunami source models although the three coasts are far from the Nankai trough. Huge slip(s) in the Nankai segment mainly contributes to the MTHs, while huge slip(s) or splay faulting in the Tokai segment hardly affects the MTHs. The tsunami source model was developed for responding to the unexpected occurrence of the 2011 Tohoku Earthquake, with 11 models along the Nanakai trough, and simulated MTHs along the Pacific coasts of the western Japan from these models exceed 10 m, with a maximum height of 34.4 m. Tsunami propagation was computed by the finite-difference method of the non-liner long-wave equations with the Corioli's force and bottom friction (Satake, 1995) in the area of 115-155 ° E and 8° S-40° N. Because water depth of the East China Sea is shallower than 200 m, the tsunami propagation is likely to be affected by the ocean bottom fiction. The 30 arc-seconds gridded bathymetry data provided by the General Bathymetric Chart of the Oceans (GEBCO-2014) are used. For long propagation of tsunami we simulated tsunamis for 24 hours after the earthquakes. This study was supported by the"New disaster mitigation research project on Mega thrust earthquakes around Nankai

  5. Reference Values for Peak Exercise Cardiac Output in Healthy Individuals.

    Science.gov (United States)

    Agostoni, Piergiuseppe; Vignati, Carlo; Gentile, Piero; Boiti, Costanza; Farina, Stefania; Salvioni, Elisabetta; Mapelli, Massimo; Magrì, Damiano; Paolillo, Stefania; Corrieri, Nicoletta; Sinagra, Gianfranco; Cattadori, Gaia

    2017-06-01

    Cardiac output (Q˙) is a key parameter in the assessment of cardiac function, its measurement being crucial for the diagnosis, treatment, and prognostic evaluation of all heart diseases. Until recently, Q˙ determination at peak exercise has been possible through invasive methods, so that normal values were obtained in studies based on small populations. Nowadays, peak Q˙ can be measured noninvasively by means of the inert gas rebreathing (IGR) technique. The present study was undertaken to provide reference values for peak Q˙ in the normal general population and to obtain a formula able to estimate peak exercise Q˙ from measured peak oxygen uptake (V˙o2). We studied 500 normal subjects (age, 44.9 ± 1.5 years; range, 18-77 years; 260 men, 240 women) who underwent a maximal cardiopulmonary exercise test with peak Q˙ measurement by IGR. In the overall study sample, peak Q˙ was 13.2 ± 3.5 L/min (men, 15.3 ± 3.3 L/min; women, 11.0 ± 2.0 L/min; P exercise was (4.4 × peak V˙o2) + 4.3 in the overall study cohort, (4.3 × peak V˙o2) + 4.5 in men, and (4.9 × peak V˙o2) + 3.6 in women. The simultaneous measurement of Q˙ and V˙o2 at peak exercise in a large sample of healthy subjects provided an equation to predict peak Q˙ from peak V˙o2 values. Copyright © 2017 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

  6. Do asthma patients prefer to monitor symptoms or peak flow?

    Science.gov (United States)

    Harver, Andrew; Humphries, C Thomas; Kotses, Harry

    2009-11-01

    We administered a 65-item survey to patients to assess preference of symptoms and peak flow to detect worsening asthma and to collect information about asthma triggers, asthma knowledge sources, and barriers to peak flow meter use. It was completed by 139 asthma patients. Survey responses were comparable for adult and pediatric patients and for those who owned peak flow meters and those who did not. But patients who owned a peak flow meter reported more severe asthma than others. On average, the patients preferred symptoms to peak flow for assessing worsening asthma. It is likely that the preference for symptom over peak flow monitoring was effort related: Patients preferred symptom monitoring because it was the easier of the two to conduct.

  7. Gamma-ray peak shapes from cadmium zinc telluride detectors

    Energy Technology Data Exchange (ETDEWEB)

    Namboodiri, M.N.; Lavietes, A.D.; McQuaid, J.H.

    1996-09-01

    We report the results of a study of the peak shapes in the gamma spectra measured using several 5 x 5 x 5 mm{sup 3} cadmium zinc telluride (CZT) detectors. A simple parameterization involving a Gaussian and an exponential low energy tail describes the peak shapes sell. We present the variation of the parameters with gamma energy. This type of information is very useful in the analysis of complex gamma spectra consisting of many peaks.

  8. Peak experiences of psilocybin users and non-users.

    Science.gov (United States)

    Cummins, Christina; Lyke, Jennifer

    2013-01-01

    Maslow (1970) defined peak experiences as the most wonderful experiences of a person's life, which may include a sense of awe, well-being, or transcendence. Furthermore, recent research has suggested that psilocybin can produce experiences subjectively rated as uniquely meaningful and significant (Griffiths et al. 2006). It is therefore possible that psilocybin may facilitate or change the nature of peak experiences in users compared to non-users. This study was designed to compare the peak experiences of psilocybin users and non-users, to evaluate the frequency of peak experiences while under the influence of psilocybin, and to assess the perceived degree of alteration of consciousness during these experiences. Participants were recruited through convenience and snowball sampling from undergraduate classes and at a musical event. Participants were divided into three groups, those who reported a peak experience while under the influence of psilocybin (psilocybin peak experience: PPE), participants who had used psilocybin but reported their peak experiences did not occur while they were under the influence of psilocybin (non-psilocybin peak experience: NPPE), and participants who had never used psilocybin (non-user: NU). A total of 101 participants were asked to think about their peak experiences and complete a measure evaluating the degree of alteration of consciousness during that experience. Results indicated that 47% of psilocybin users reported their peak experience occurred while using psilocybin. In addition, there were significant differences among the three groups on all dimensions of alteration of consciousness. Future research is necessary to identify factors that influence the peak experiences of psilocybin users in naturalistic settings and contribute to the different characteristics of peak experiences of psilocybin users and non-users.

  9. Some nonlinear parameters of PP intervals of pulse main peaks

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The PP intervals of pulse main peaks from healthy and unhealthy people (arrhythmia) have different nonlinear characteristics. In this paper, the extraction of PP intervals of pulse main peaks is achieved by picking up P peaks of pulse wave with wavelet transform. Furthermore, several nonlinear parameters (correlative dimensions, maximum Lyapunov exponents, complexity and approximate entropy) of the PP intervals of pulse main peaks extracted from normal and unhealthy pulse signals are calculated, with the results showing that these nonlinear parameters calculated from the main wave interval signals are helpful for analyzing human's health state and diagnosing heart diseases.

  10. Peak load pricing in the electric utility industry

    Energy Technology Data Exchange (ETDEWEB)

    Wenders, J.T.

    In the electric utility industry, cost minimization requires that heterogeneous electric generation technologies be used to produce electricity demands of different durations. In contrast to the conclusions of traditional peak-load pricing theory, the existence of a heterogeneous capital stock means that off-peak marginal cost prices almost always should include some marginal capacity costs, and that the profit maximizing regulated electric utility may set peak price above marginal cost and off-peak price below marginal cost in order to encourage the expansion of capital-intensive base load generating capacity. (auth)

  11. Nonlinear preprocessing method for detecting peaks from gas chromatograms

    Directory of Open Access Journals (Sweden)

    Min Hyeyoung

    2009-11-01

    Full Text Available Abstract Background The problem of locating valid peaks from data corrupted by noise frequently arises while analyzing experimental data. In various biological and chemical data analysis tasks, peak detection thus constitutes a critical preprocessing step that greatly affects downstream analysis and eventual quality of experiments. Many existing techniques require the users to adjust parameters by trial and error, which is error-prone, time-consuming and often leads to incorrect analysis results. Worse, conventional approaches tend to report an excessive number of false alarms by finding fictitious peaks generated by mere noise. Results We have designed a novel peak detection method that can significantly reduce parameter sensitivity, yet providing excellent peak detection performance and negligible false alarm rates from gas chromatographic data. The key feature of our new algorithm is the successive use of peak enhancement algorithms that are deliberately designed for a gradual improvement of peak detection quality. We tested our approach with real gas chromatograms as well as intentionally contaminated spectra that contain Gaussian or speckle-type noise. Conclusion Our results demonstrate that the proposed method can achieve near perfect peak detection performance while maintaining very small false alarm probabilities in case of gas chromatograms. Given the fact that biological signals appear in the form of peaks in various experimental data and that the propose method can easily be extended to such data, our approach will be a useful and robust tool that can help researchers highlight valid signals in their noisy measurements.

  12. Adaptive Peak Frequency Estimation Using a Database of PARCOR Coefficients

    Directory of Open Access Journals (Sweden)

    Iiguni Youji

    2005-01-01

    Full Text Available This paper presents an adaptive peak frequency estimation method using a database that stores PARCOR coefficients as key attributes and the corresponding peak frequencies as nonkey attributes. The least-square lattice algorithm is used to recursively estimate the PARCOR coefficients to adapt to changing circumstances. The nearest neighbor to the current PARCOR coefficient is retrieved from the database, and the corresponding peak frequency is regarded as the estimation. A simultaneous execution of database construction and peak estimation with database update is performed to accelerate the processing time and to improve the estimation accuracy.

  13. Peak compression technique in high-performance liquid chromatography

    Institute of Scientific and Technical Information of China (English)

    WEI YuXia; WANG Lin; XlAO ShengYuan; QING Hong; ZHU Yong; HU GaoFei; DENG YuLin

    2009-01-01

    Peak compression technique based on the difference of the solute migration velocity in two different mobile phases was described theoretically and confirmed using benzaldehyde and 4-hydroxyquinoline (4-HQ) as model compounds.After peak compression,the peak compression factors (the ratio of peak width at half-height under non-compression and that under compression condition) of benzaldehyde and 4-HQ were 0.19 and 0.13,respectively.By this application of the peak compression technique to the mixture,both enhanced peak height and good separation were obtained in one run cycle.This peak compression technique was introduced to determine benzaldehyde from semicarbazide-sensitive amine oxidase-catalyzed enzymetic reaction in order to illustrate the applicability of this technique to the real sample.As a result,the peak was compressed effectively,and 4.94-fold,19.3-fold and 5.74-fold enhancement in peak height,plate number and signal to noise ratio were also achieved,respectively.

  14. Zener Relaxation Peak in an Fe-Cr-Al Alloy

    Institute of Scientific and Technical Information of China (English)

    周正存; 程和法; 宫晨利; 魏健宁; 韩福生

    2002-01-01

    We have studied the temperature spectra of internal friction and relative dynamic modulus of the Fe-(25 wt%)Cr-(5wt%)Al alloy with different grain sizes. It is found that a peak appears in the internal friction versus temperature plot at about 550°C. The peak is of a stable relaxation and is reversible, which occurs not only during heating but also during cooling. Its activation energy is 2.5 (± 0.15) eV in terms of the Arrhenius relation. In addition, the peak is not obvious in specimens with a smaller grain size. It is suggested that the peak originates from Zener relaxation.

  15. The Method of Single Peak Fourier Analysis of Measuring the Size of Mosaic Block and Microstrain by X-ray Diffraction

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The values of mosaic block size and microstrain measured by the method of Voigt function are sometimes largely erroneous and difficult to be revised. In this paper, the causes of the “hook effect” which inevitably exists in the method of Fourier analysis are explained; then the method for resolving this effect is put forward; and finally the method of hypothetical function is used to simplify the method of the Fourier analysis from multi-peak to single-peak. By introducing the parameter m, this method can not only indicate the degree of errors, but also revise them as well. It is simple, clear and able to accomplish the intricate pattern calculation quickly by the aid of computer. In the end, we argue the identity between method of the approximate function and the Fourier analysis, and give a more accurate proportional coefficient k.

  16. HIERARCHIC SKELETAL ORGANIZATION - A FACTOR REGULATING THE STRUCTURE OF FATIGUE INJURIES. PART II. HYPOTHETICAL MODEL OF FORMATION AND DISTRUPTION OF BONDS BETWEEN CRYSTALLITE ASSOCIATIONS

    Directory of Open Access Journals (Sweden)

    A. S. Avrunin

    2010-01-01

    Full Text Available The authors discuss the questions concerning local structural-temporal changes in skeletal mineralization degree, local hyper-mineralization, the role of the spatial gradient of skeletal mineralization in forces distribution during locomotion, microstructural distribution of crystallite associations, ultrastructural mineral matrix transformation in the process of its formation. Hypothetical mechanisms of joining crystallite associations into a unified mineral complex are suggested; a hypothetical spatial structure of junction formation between the nearest crystallite associations is described, as well as a supposed schema of mineral massif destruction and restoration of disrupted connections.

  17. The conservation and application of three hypothetical protein coding gene for direct detection of Mycobacterium tuberculosis in sputum specimens.

    Directory of Open Access Journals (Sweden)

    Lianhua Qin

    Full Text Available BACKGROUND: Accurate and early diagnosis of tuberculosis (TB is of major importance in the control of TB. One of the most important technical advances in diagnosis of tuberculosis is the development of nucleic acid amplification (NAA tests. However, the choice of the target sequence remains controversial in NAA tests. Recently, interesting alternatives have been found in hypothetical protein coding sequences from mycobacterial genome. METHODOLOGY/PRINCIPAL FINDINGS: To obtain rational biomarker for TB diagnosis, the conservation of three hypothetical genes was firstly evaluated in 714 mycobacterial strains. The results showed that SCAR1 (Sequenced Characterized Amplified Region based on Rv0264c coding gene showed the highest conservation (99.8% and SCAR2 based on Rv1508c gene showed the secondary high conservation (99.7% in M. tuberculosis (MTB strains. SCAR3 based on Rv2135c gene (3.2% and IS6110 (8% showed relatively high deletion rate in MTB strains. Secondly, three SCAR markers were evaluated in 307 clinical sputum from patients in whom TB was suspected or patients with diseases other than TB. The amplification of IS6110 and 16SrRNA sequences together with both clinical and bacteriological identification was as a protocol to evaluate the efficacy of SCAR markers. The sensitivities and specificities, positive predictive value (PPV and negative predictive value (NPV of all NAA tests were higher than those of bacteriological detection. In four NAA tests, IS6110 and SCAR3 showed the highest PPV (100% and low NPV (70% and 68.8%, respectively, and SCAR1 and SCAR2 showed the relatively high PPV and NPV (97% and 82.6%, 95.6% and 88.8%, respectively. CONCLUSIONS/SIGNIFICANCE: Our result indicated that SCAR1 and SCAR2 with a high degree of sequence conservation represent efficient and promising alternatives as NAA test targets in identification of MTB. Moreover, the targets developed from this study may provide more alternative targets for the

  18. Determinants of physician empathy during medical education: hypothetical conclusions from an exploratory qualitative survey of practicing physicians

    Science.gov (United States)

    2014-01-01

    Background Empathy is an outcome-relevant physician characteristic and thus a crucial component of high-quality communication in health care. However, the factors that promote and inhibit the development of empathy during medical education have not been extensively researched. Also, currently there is no explicit research on the perspective of practicing physicians on the subject. Therefore the aim of our study was to explore physicians’ views of the positive and negative influences on the development of empathy during their medical education, as well as in their everyday work as physicians. Method We administered a written Qualitative Short Survey to 63 physicians in seven specialties. They were able to respond anonymously. Our open-ended question was: “What educational content in the course of your studies and/or your specialist training had a positive or negative effect on your empathy?” We analyzed the data using thematic content analysis following Mayring’s approach. Results Forty-two physicians took part in our survey. All together, they mentioned 68 specific factors (37 positive, 29 negative, 2 neutral) from which six themes emerged: 1. In general, medical education does not promote the development of empathy. 2. Recognizing the psycho-social dimensions of care fosters empathy. 3. Interactions with patients in medical practice promote empathy. 4. Physicians’ active self-development through reflective practice helps the development of empathy. 5. Interactions with colleagues can both promote and inhibit empathy through their role modeling of empathic and non-empathic behavior. 6. Stress, time pressure, and adverse working conditions are detrimental to empathy development. Conclusions Our results provide an overview of what might influence the development of clinical empathy, as well as hypothetical conclusions about how to promote it. Reflective practice seems to be lacking in current medical curricula and could be incorporated. Raising physicians

  19. Trans-Atlantic tsunamis: Simulations of the 1755 Lisbon and of hypothetical Puerto Rico trench earthquake tsunamis

    Science.gov (United States)

    Barkan, R.; ten Brink, U. S.; Lin, J.

    2008-12-01

    The great Lisbon earthquake of November 1, 1755 with an estimated moment magnitude of 8.5-9.0, was the most destructive earthquake in European history. Run-ups from a trans-oceanic tsunami were reported in the Caribbean, Brazil and Newfoundland, but there were no reports along the U.S. East Coast. Previous attempts to characterize the 1755 Lisbon earthquake source utilized geophysical surveys and modeling of the near-field earthquake intensity and near-field tsunami run-up. Here we attempt to constrain the source parameters using the far-field tsunami effects because trans-oceanic tsunami run-ups are less influenced by near source bathymetry and are unaffected by triggered submarine landslides at the source. Our far- and near-field tsunami simulations based on relative amplitude comparison, limit the earthquake source area to a region located south of Gorringe Bank in the center of Horseshoe Plain. This location contrasts with previously suggested sources such as the Marqués de Pombal and Gulf of Cadiz faults, which are farther to the east. Based on relative wave amplitude and polarity, the earthquake was likely a thrust event on a fault striking about 345 deg. and dipping to the ENE which is almost perpendicular to the trend of Gorringe Bank. Gorringe Bank, the Madeira-Tore Rise (MTR), and the Azores appear to have acted as topographic scatterers for tsunami energy, shielding most of the U.S. East Coast (with the exception of Florida) from the 1755 Lisbon tsunami. By contrast, sources located west of the MTR or in the Gulf of Cadiz could potentially affect the southeastern coast of the U.S. The Azores-Iberia plate boundary west of the MTR is characterized by strike-slip faults, which are less likely to generate tsunamis, but the Gulf of Cadiz may have thrust faults. Simulations of a hypothetical M8.9 tsunamigenic earthquake in the Puerto Rico trench were conducted to investigate its possible effect on coastal Europe. The recorded history of Western Europe extends

  20. Assessing peak aerobic capacity in Dutch law enforcement officers

    Directory of Open Access Journals (Sweden)

    Harriet Wittink

    2015-06-01

    Full Text Available Objectives: To cross-validate the existing peak rate of oxygen consumption (VO2peak prediction equations in Dutch law enforcement officers and to determine whether these prediction equations can be used to predict VO2peak for groups and in a single individual. A further objective was to report normative absolute and relative VO2peak values of a sample of law enforcement officers in the Netherlands. Material and Methods: The peak rate of oxygen consumption (ml×kg–1×min–1 was measured using a maximal incremental bicycle test in 1530 subjects, including 1068 male and 461 female police officers. Validity of the prediction equations for groups was assessed by comparing predicted VO2peak with measured VO2peak using paired t-tests. For individual differences limits of agreement (LoA were calculated. Equations were considered valid for individuals when the difference between measured and predicted VO2peak did not exceed ±1 metabolic equivalent (MET in 95% of individuals. Results: None of the equations met the validity criterion of 95% of individuals having ±1 MET difference or less than the measured value. Limits of agreement (LoAs were large in all predictions. At the individual level, none of the equations were valid predictors of VO2peak (ml×kg–1×min–1. Normative values for Dutch law enforcement officers were presented. Conclusions: Substantial differences between measured and predicted VO2peak (ml×kg–1×min–1 were found. Most tested equations were invalid predictors of VO2peak at group level and all were invalid at individual levels.

  1. Assessing peak aerobic capacity in Dutch law enforcement officers.

    Science.gov (United States)

    Wittink, Harriet; Takken, Tim; de Groot, Janke; Reneman, Michiel; Peters, Roelof; Vanhees, Luc

    2015-01-01

    To cross-validate the existing peak rate of oxygen consumption (VO2peak) prediction equations in Dutch law enforcement officers and to determine whether these prediction equations can be used to predict VO2peak for groups and in a single individual. A further objective was to report normative absolute and relative VO2peak values of a sample of law enforcement officers in the Netherlands. The peak rate of oxygen consumption (ml×kg-1×min-1) was measured using a maximal incremental bicycle test in 1530 subjects, including 1068 male and 461 female police officers. Validity of the prediction equations for groups was assessed by comparing predicted VO2peak with measured VO2peak using paired t-tests. For individual differences limits of agreement (LoA) were calculated. Equations were considered valid for individuals when the difference between measured and predicted VO2peak did not exceed ±1 metabolic equivalent (MET) in 95% of individuals. None of the equations met the validity criterion of 95% of individuals having ±1 MET difference or less than the measured value. Limits of agreement (LoAs) were large in all predictions. At the individual level, none of the equations were valid predictors of VO2peak (ml×kg-1×min-1). Normative values for Dutch law enforcement officers were presented. Substantial differences between measured and predicted VO2peak (ml×kg-1×min-1) were found. Most tested equations were invalid predictors of VO2peak at group level and all were invalid at individual levels. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

  2. Online junction temperature measurement using peak gate current

    DEFF Research Database (Denmark)

    Baker, Nick; Munk-Nielsen, Stig; Iannuzzo, Francesco

    2015-01-01

    A new method for junction temperature measurement of MOS-gated power semiconductor switches is presented. The measurement method involves detecting the peak voltage over the external gate resistor of an IGBT or MOSFET during turn-on. This voltage is directly proportional to the peak gate current...

  3. Quality Assurance in the Determination of Overlapping Peak Areas

    DEFF Research Database (Denmark)

    Christensen, L.H.; Heydorn, K.

    1987-01-01

    The ability of different computer programs to yield accurate peak areas in statistical control in the case of partially overlapping photopeaks has been tested by the Analysis of Precision. A modified Covell method, two commercially available peak-fitting programs from Nuclear Data and Ortec, and ...

  4. Psychological Preparation for Peak Performance in Sports Competition

    Science.gov (United States)

    Ohuruogu, Ben; Jonathan, Ugwuanyi I.; Ikechukwu, Ugwu Jude

    2016-01-01

    This paper attempts to make an overview of various techniques, sport psychologist adopt in psychological preparation of athletes for peak performance. To attain peak performance in sports competitions, coaches and athletes should not base their prospect on physical training on sport skills alone rather should integrate both the mental and physical…

  5. Probabilistic peak detection for first-order chromatographic data

    NARCIS (Netherlands)

    Lopatka, M.; Vivó-Truyols, G.; Sjerps, M.J.

    2014-01-01

    We present a novel algorithm for probabilistic peak detection in first-order chromatographic data. Unlike conventional methods that deliver a binary answer pertaining to the expected presence or absence of a chromatographic peak, our method calculates the probability of a point being affected by suc

  6. A rise in peak performance age in female athletes.

    Science.gov (United States)

    Elmenshawy, Ahmed R; Machin, Daniel R; Tanaka, Hirofumi

    2015-06-01

    It was reported in 1980s that ages at which peak performance was observed had remained remarkably stable in the past century, although absolute levels of athletic performance increased dramatically for the same time span. The emergence of older (masters) athletes in the past few decades has changed the demographics and age-spectrum of Olympic athletes. The primary aim of the present study was to determine whether the ages at which peak performance was observed had increased in the recent decades. The data spanning 114 years from the first Olympics (1898) to the most recent Olympics (2014) were collected using the publically available data. In the present study, ages at which Olympic medals (gold, silver, and bronze) were won were used as the indicators of peak performance age. Track and field, swimming, rowing, and ice skating events were analyzed. In men, peak performance age did not change significantly in most of the sporting events (except in 100 m sprint running). In contrast, peak performance ages in women have increased significantly since 1980s and consistently in all the athletic events examined. Interestingly, as women's peak performance age increased, they became similar to men's peak ages in many events. In the last 20-30 years, ages at which peak athletic performance is observed have increased in women but not in men.

  7. Peaked Periodic Wave Solutions to the Broer–Kaup Equation

    Science.gov (United States)

    Jiang, Bo; Bi, Qin-Sheng

    2017-01-01

    By qualitative analysis method, a sufficient condition for the existence of peaked periodic wave solutions to the Broer–Kaup equation is given. Some exact explicit expressions of peaked periodic wave solutions are also presented. Supported by National Nature Science Foundation of China under Grant No. 11102076 and Natural Science Fund for Colleges and Universities in Jiangsu Province under Grant No. 15KJB110005

  8. Deformation Induced Internal Friction Peaks in Nanocrystalline Nickel

    Institute of Scientific and Technical Information of China (English)

    LI Ping-Yun; ZHANG Xi-Yan; NI Hai-Tao; CAO Zhen-Hua; MENG Xiang-Kang

    2012-01-01

    We report the mechanical spectroscopy study of the cold-rolling induced dynamical behavior of crystalline defects in nanocrystalline (NC) nickel. The results show that internal friction (IF) peaks in NC nickel can be induced by cold-rolling. An IF peak, originating from dislocation activity, occurs when the strain is in the range of 9.7-32.8%. Two Bordoni peaks occur when the strain is 39.0% and an IF peak associated with deformation twinning appears when the strain is 42.6%. These results mean that deformation of NC nickel is mediated by different kinds of defects as the strain increases.%We report the mechanical spectroscopy study of the cold-rolling induced dynamical behavior of crystalline defects in nanocrystalline (NC) nickel The results show that internal friction (IF) peaks in NC nickel can be induced by cold-rolling.An IF peak,originating from dislocation activity,occurs when the strain is in the range of 9.7- 32.8%.Two Bordoni peaks occur when the strain is 39.0% and an IF peak associated with deformation twinning appears when the strain is 42.6%.These results mean that deformation of NC nickel is mediated by different kinds of defects as the strain increases.

  9. OBSERVATION OF ENERGY DISSIPATION PEAK IN POLYSTYRENE MELT ABOVE Tg

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In this paper two different kinds of dynamic mechanical techniques (inversed torsion pendulum and energy dissipation apparatus) were used to study the dynamic behavior of atactic monodisperse polystyrene above glass transition.The plots of energy dissipation versus temperature were presented for two atactic polystyrene samples. An apparent energy dissipation peak occurred above Tg in each plot measured by the inversed torsion pendulum, and simultaneously the sample was found to flow assuredly at the moment. To exclude the influence of the flow and demonstrate there was a peak indeed above Tg, the energy dissipation apparatus was used, in which the samples were put into a cup. An obvious peak appeared,and it was in agreement with the peak observed by the inversed torsion pendulum. On basis of the results measured by the two kinds of apparatus, a conclusion is drawn that a peak occurrs above Tg, which gives a manifestation for the existence of the liquid-liquid transition.

  10. Maximizing utilization of sport halls during peak hours

    DEFF Research Database (Denmark)

    Iversen, Evald Bundgård; Forsberg, Peter

    be increased during peak hours. DATA AND METHODOLOGYData is collected by observation of activities during two weeks on for example whether halls are used or not; the amount of playing field used; and number of participants (Iversen, 2012). Data on 1.331 activities in 36 sport halls across 4 municipalities have...... been collected. RESULTS The number of participants per activity is higher during peak hours, which is expected when demand is high. However, the usage of sport floor only differs slightly between peak and low hours. Both during peak and low hours on average 80-100 per cent of floor space is used......BACKGROUNDDuring peak hours (4.30pm-8pm) demand for timeslots in sport halls in Denmark are high and there are few timeslots available. Further, focus on how public resources are spent most efficient is increasing (Iversen, 2013). This makes it interesting to analyse how utilization could...

  11. Impact of Smart Grid Technologies on Peak Load to 2050

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The IEA's Smart Grids Technology Roadmap identified five global trends that could be effectively addressed by deploying smart grids. These are: increasing peak load (the maximum power that the grid delivers during peak hours), rising electricity consumption, electrification of transport, deployment of variable generation technologies (e.g. wind and solar PV) and ageing infrastructure. Along with this roadmap, a new working paper -- Impact of Smart Grid Technologies on Peak Load to 2050 -- develops a methodology to estimate the evolution of peak load until 2050. It also analyses the impact of smart grid technologies in reducing peak load for four key regions; OECD North America, OECD Europe, OECD Pacific and China. This working paper is a first IEA effort in an evolving modelling process of smart grids that is considering demand response in residential and commercial sectors as well as the integration of electric vehicles.

  12. Arrival Times of Gravitational Radiation Peaks for Binary Inspiral

    CERN Document Server

    Price, Richard H

    2016-01-01

    Modeling of gravitational waves (GWs) from binary black hole inspiral brings together early post-Newtonian waveforms and late quasinormal ringing waveforms. Attempts to bridge the two limits without recourse to numerical relativity involve predicting the time of the peak GW amplitude. This prediction will require solving the question of why the peak of the "source," i.e., the peak of the binary angular velocity, does not correspond to the peak of the GW amplitude. We show here that this offset can be understood as due to the existence two distinct components of the radiation: the "direct" radiation analogous to that in flat spacetime, and "scattered" radiation associated with curved spacetime. The time dependence of these two components, and of their relative phases determines the location of the peak amplitude. We use a highly simplified model to clarify the twocomponent nature of the source, then demonstrate that the explanation is valid also for an extreme mass ratio binary inspiral.

  13. Calculation of isodose curves from initial neutron radiation of a hypothetical nuclear explosion using Monte Carlo Method

    Energy Technology Data Exchange (ETDEWEB)

    Medeiros, Marcos P.C.; Rebello, Wilson F.; Andrade, Edson R., E-mail: rebello@ime.eb.br, E-mail: daltongirao@yahoo.com.br [Instituto Militar de Engenharia (IME), Rio de Janeiro, RJ (Brazil). Secao de Engenharia Nuclear; Silva, Ademir X., E-mail: ademir@nuclear.ufrj.br [Corrdenacao dos Programas de Pos-Graduacao em Egenharia (COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Programa de Engenharia Nuclear

    2015-07-01

    Nuclear explosions are usually described in terms of its total yield and associated shock wave, thermal radiation and nuclear radiation effects. The nuclear radiation produced in such events has several components, consisting mainly of alpha and beta particles, neutrinos, X-rays, neutrons and gamma rays. For practical purposes, the radiation from a nuclear explosion is divided into {sup i}nitial nuclear radiation{sup ,} referring to what is issued within one minute after the detonation, and 'residual nuclear radiation' covering everything else. The initial nuclear radiation can also be split between 'instantaneous or 'prompt' radiation, which involves neutrons and gamma rays from fission and from interactions between neutrons and nuclei of surrounding materials, and 'delayed' radiation, comprising emissions from the decay of fission products and from interactions of neutrons with nuclei of the air. This work aims at presenting isodose curves calculations at ground level by Monte Carlo simulation, allowing risk assessment and consequences modeling in radiation protection context. The isodose curves are related to neutrons produced by the prompt nuclear radiation from a hypothetical nuclear explosion with a total yield of 20 KT. Neutron fluency and emission spectrum were based on data available in the literature. Doses were calculated in the form of ambient dose equivalent due to neutrons H*(10){sub n}{sup -}. (author)

  14. Factors associated with attitude and hypothetical behaviour regarding brain death and organ transplantation: comparison between medical and other university students.

    Science.gov (United States)

    Ohwaki, Kazuhiro; Yano, Eiji; Shirouzu, Makiko; Kobayashi, Aya; Nakagomi, Tadayoshi; Tamura, Akira

    2006-01-01

    The aim of this study was to investigate the factors, including knowledge, that determine an individual's attitudes and behaviours regarding brain death and organ transplantation using questionnaires among medical and other university students. A total of 522 students (388 medical and 134 other) answered a questionnaire. The survey included the individual's knowledge about brain death, attitudes towards brain death and organ transplantation, and hypothetical behaviours assuming their willingness to donate their own or their family's organs. Medical students were more likely to have knowledge about brain death and to accept brain death and organ transplantation compared with other students, while there was no difference in their willingness to donate their own or their family's organs. Logistic regression analysis was used to assess the effects of various factors on the attitudes and behaviours. In both medical and other students, confidence in brain-death diagnosis by doctors was independently associated with their willingness to donate their own organs after the adjustment for other factors, including knowledge (odds ratio [OR], 1.85; 95% confidence interval [CI], 1.15 to 2.97 and OR, 4.97; 95% CI, 1.01 to 24.39, respectively). An increase in knowledge may cause positive attitudes towards brain death and organ transplant. Meanwhile, reducing uncertainty about the brain-death diagnostic process might have a beneficial effect on the willingness to donate organs.

  15. Altruistic reasoning in adolescent-parent dyads considering participation in a hypothetical sexual health clinical trial for adolescents.

    Science.gov (United States)

    Chávez, Noé Rubén; Williams, Camille Y; Ipp, Lisa S; Catallozzi, Marina; Rosenthal, Susan L; Breitkopf, Carmen Radecki

    2016-04-01

    Altruism is a well-established reason underlying research participation. Less is known about altruism in adolescent-parent decision-making about clinical trials enrolling healthy adolescents. This qualitative investigation focused on identifying spontaneous statements of altruism within adolescent-parent (dyadic) discussions of participation in a hypothetical phase I clinical trial related to adolescent sexual health. Content analysis revealed several response patterns to each other's altruistic reasoning. Across 70 adolescent-parent dyads in which adolescents were 14-17 years of age and 91% of their parents were mothers, a majority (61%) of dyadic discussions included a statement reflecting altruism. Parents responded to adolescents' statements of altruism more frequently than adolescents responded to parents' statements. Responses included: expresses concern, reiterates altruistic reasoning, agrees with altruistic reasoning, and adds to/expands altruistic reasoning. Since an altruistic perspective was often balanced with concerns about risk or study procedures, researchers cannot assume that altruism will directly lead to study participation. Optimizing the informed consent process for early phase clinical trials involving healthy adolescents may include supporting parents to have conversations with their adolescents which will enhance their capacity to consider all aspects of trial participation.

  16. Improving environmental assessments by integrating Species Sensitivity Distributions into environmental modeling: examples with two hypothetical oil spills.

    Science.gov (United States)

    Bejarano, Adriana C; Mearns, Alan J

    2015-04-15

    A three dimensional (3D) trajectory model was used to simulate oil mass balance and environmental concentrations of two 795,000 L hypothetical oil spills modeled under physical and chemical dispersion scenarios. Species Sensitivity Distributions (SSD) for Total Hydrocarbon Concentrations (THCs) were developed, and Hazard Concentrations (HC) used as levels of concern. Potential consequences to entrained water column organisms were characterized by comparing model outputs with SSDs, and obtaining the proportion of species affected (PSA) and areas with oil concentrations exceeding HC5s (Area ⩾ HC5). Under the physically-dispersed oil scenario ⩽ 77% of the oil remains on the water surface and strands on shorelines, while with the chemically-dispersed oil scenario ⩽ 67% of the oil is entrained in the water column. For every 10% increase in chemical dispersion effectiveness, the average PSA and Area ⩾ HC5 increases (range: 0.01-0.06 and 0.50-2.9 km(2), respectively), while shoreline oiling decreases (⩽ 2919 L/km). Integrating SSDs into modeling may improve understanding of scales of potential impacts to water column organisms, while providing net environmental benefit comparison of oil spill response options.

  17. Heat propagation in and around the deep repository. Thermal calculations applied to three hypothetical sites: Aberg, Beberg and Ceberg

    Energy Technology Data Exchange (ETDEWEB)

    Ageskog, L.; Jansson, Patrik [VBB Anlaeggning AB (Sweden)

    1999-01-01

    The purpose of the present study is to demonstrate the modelling of the thermal process in and around the deep repository for spent fuel. The model was developed in the general finite element program ANSYS and applied to the three hypothetical sites Aberg, Beberg and Ceberg included in the SR 97 analyse system. The canister emplacement in the repository was analysed based on certain criteria regarding the temperature on the canister surface. This was done with consideration to natural deviations in various thermal parameters as well as to the risk of a gap opening up between the canister surface and the bentonite buffer. The consequence of the latter was analysed separately as part of the study. The heat load in the model was applied stepwise, followingan assumed time schedule for the actual deposition work. The calculations were extended to 1,000 years after the commencement of the deposition work. The outcome of the calculation is presented as coloured prints of isotherms in and around the repository at certain time intervals.

  18. A 3-dimensional numerical simulation of the atmospheric injection of aerosols by a hypothetical basaltic fissure eruption

    Science.gov (United States)

    Tripoli, Gregory J.; Thompson, Starley L.

    1988-01-01

    Researchers simulated the atmospheric response to a hypothetical basaltic fissure eruption using heating rates based on the Roza flow eruption. The simulation employs the Colorado State University Regional Atmospheric Model (RAMS) with scavenging effects. The numerical model is a three-dimensional non-hydrostatic time-split compressible cloud/mesoscale model. Explicit microphysics include prediction of cloud, rain, crystal, and hail precipitation types. Nucleation and phoretic scavenging are predicted assuming that the pollutant makes an effective cloud droplet nucleus. Smoke is carried as a passive tracer. Long and short wave radiation heating tendencies, including the effects of the smoke, are parameterized. The longwave emission by the lava surface is neglected in the parameterization and included as an explicit heating term instead. A regional scale domain of 100 x 100 km in the horizontal and 22 km high is used. The horizontal grid spacing is taken to be 2 km and the vertical spacing is taken to be 0.75 km. The initial atmospheric state is taken to be horizontally homogenous and based on the standard atmospheric sounding. The fissure is assumed to be 90 km long and oriented in a zig/zag pattern.

  19. Analysis of a hypothetical loss of coolant accident in a Konvoi type NPP by GASFLOW and COCOSYS

    Energy Technology Data Exchange (ETDEWEB)

    Benz, Stefan; Royl, Peter [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany); Band, Sebastian [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (GRS), Koeln (Germany)

    2013-07-01

    The 3D computational fluid dynamics code GASFLOW and the German containment code system COCOSYS, which is based on a lumped-parameter approach, are used to simulate the hydrogen-air-steam distribution and hydrogen mitigation in a Konvoi type nuclear power plant in a postulated hypothetical core melt accident. A break in a coolant loop and the subsequent loss of the coolant causes a strong heat-up of the core. As a consequence hydrogen is produced by oxidation of cladding tubes. The residual steam and the produced hydrogen are released into the containment through the break in the coolant loop. Without suitable counter measures, sensitive mixtures can build up with a combustion potential which could threaten the integrity of the containment. A model of a Konvoi type nuclear power plant which is equipped with passive autocatalytic recombiners is used to simulate such accident scenario. COCOSYS allows comprehensive simulation of all relevant processes of severe accidents, whereas GASFLOW is primarily designed to simulate the distribution of steam and hydrogen within the containment. This paper presents the comparison of GASFLOW and COCOSYS simulation results for the in-vessel phase of the selected accident. (orig.)

  20. Paediatric biobanks: opinions, feelings and attitudes of parents towards the specimen donation of their sick children to a hypothetical biobank.

    Science.gov (United States)

    Salvaterra, Elena; Locatelli, Federica; Strazzer, Sandra; Borgatti, Renato; D'angelo, Grazia; Lenzi, Leonardo

    2014-01-01

    Over the last years, the storing of biological materials from children for research purposes in biobanks has become the subject of an intense debate in the scientific and ethical communities on a global level. Paediatric biobanks are an important resource for the development of translational research. At the same time, paediatric biobanks are ethically 'sensitive' due to the unique issues they raise. In this study, we explore opinions, feelings and attitudes of parents towards the specimen donation of their sick children to a hypothetical biobank. According to a qualitative methodology based on focus groups, we analysed parents' views, perceptions and inclinations towards typical ethical, legal and social aspects of paediatric biobanks such as proxy consent, minor assent, privacy protection and return of results. Our study confirms the need for specific policies dedicated to paediatric biobanks by highlighting how the nature of the disease affecting children may influence the parents' opinions and decisions towards the enrolment of their children in biobank-based research studies.