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Sample records for human internal organs

  1. Human Capital Development in the International Organization: Rhetoric and Reality

    Science.gov (United States)

    Kulvisaechana, Somboon

    2006-01-01

    Purpose: The purpose of this study is to present empirical evidence of the nature of corporate rhetoric in developing human capital and how it becomes embedded within a large international organization operating in the Nordic region. The qualitative case study aims to examine the sensemaking of individual managers, and how human capital rhetoric…

  2. THE HUMAN RIGHTS APPROACH TO MARKETS IN THE WORLD TRADE ORGANIZATION, UNITED NATIONS AND INTERNATIONAL LABOUR ORGANIZATION

    Directory of Open Access Journals (Sweden)

    Mehari Fisseha

    2014-07-01

    Full Text Available In the shadow of World War II’s end, unprecedented discourse regarding international human rights was birthed from knowledge regarding the gross abuses that took place and subsequent shock that the civilized world had no international legislation in place to counter similar, future atrocities. In 1948, the International Labour Organization (ILO adopted the Freedom of Association and Protection of the Right to Organise Convention while, in the same year, the United Nations (UN adopted the Universal Declaration of Human Rights [Swepston 1998, p.169]. The comparatively younger World Trade Organization (WTO has been both condemned and heralded for its handling, and lack thereof, of human rights violations. In the formidable wake of globalisation, all three organizations have had to bind their human rights policies to economics, thereby enhancing the interconnectivity of the entities and, by extension, international policy. The following, critical comment explores the history and current state of UN, ILO, and WTO human rights’ approaches to market policy, affording particular attention to recommendations for amending the policies in order to foster greater cohesion and address one of the most pressing human rights issues of the twenty-first century.

  3. The patterns and expression of KDR in normal tissues of human internal organs.

    Science.gov (United States)

    Huang, Jianfei; Zhu, Huijun; Wang, Xudong; Tang, Qi; Huang, Hua; Wu, Kerong; Zhu, Jin; Feng, Zhenqing; Shi, Gongshen

    2011-12-01

    KDR has been implicated for playing an important role in the formation of new blood vessels and in solid tumor growth. It was considered as one of the most important regulators of angiogenesis and a key target in anticancer treatment. In the present study, we characterized KDR mRNA and protein expression in normal tissues of perinatal and adult tissues using One-step Real-Time RT-PCR and immunohistochemistry with a self-made anti-KDR antibody. The expression of KDR mRNA and protein in perinatal internal organs were all higher than in adult organs including brain, kidney, liver, lung and heart, respectively. KDR protein was presented in the cell plasma membrane of human internal tissues. The expression of KDR protein was raised in macrophage of spleen, and decreased in neurons of brain, myocardium, bronchial epithelial cells and alveolar epithelial cell, proximal and distal tubules cells, and hepatic cells with the maturity process of human organs. Notably, the order of KDR protein expression from highest to lowest is as follows: brain, liver, heart, kidney, and lung in adult tissues with statistically significant. It follows that how to balance the potential therapeutic side effect with human internal organs in targeted therapy of over-expressing KDR tumor.

  4. Comparison of LAIR-1 genetic pathways in murine vs human internal organs.

    Science.gov (United States)

    Sun, Shuqiu; Jiao, Yan; Wei, Wei; Postlethwaite, Arnold E; Gu, Weikuan; Sun, Dianjun

    2014-11-15

    Growing evidence suggests that defective expression or dysfunction of LAIR-1, a novel immunoinhibitory receptor for collagen, is closely associated with some autoimmune diseases, cancers, as well as viral infections. We analyzed the variation of LAIR-1 genetic pathways in murine versus human internal organs, including the lung and brain. The results showed that, under physiological conditions, LAIR-1 links more closely to the common genes in mouse than in human, which poses tissue specificity. It means that mice experimental data in relation to the role of LAIR-1 immune regulation may be overestimated when applied to assess human conditions. Moreover, we found that the in vivo interaction of LAIR-1 with LAIR-2 rarely occurs, implying that the species difference in LAIR-1 genetic pathways could not be primarily attributed to the existence of human LAIR-2. In summary, this study opens the door for insight into LAIR-1 functions inside the human body, and raises concern as to extrapolative credibility of the murine model in biomedical research.

  5. Cis-regulatory underpinnings of human GLI3 expression in embryonic craniofacial structures and internal organs.

    Science.gov (United States)

    Abbasi, Amir A; Minhas, Rashid; Schmidt, Ansgar; Koch, Sabine; Grzeschik, Karl-Heinz

    2013-10-01

    The zinc finger transcription factor Gli3 is an important mediator of Sonic hedgehog (Shh) signaling. During early embryonic development Gli3 participates in patterning and growth of the central nervous system, face, skeleton, limb, tooth and gut. Precise regulation of the temporal and spatial expression of Gli3 is crucial for the proper specification of these structures in mammals and other vertebrates. Previously we reported a set of human intronic cis-regulators controlling almost the entire known repertoire of endogenous Gli3 expression in mouse neural tube and limbs. However, the genetic underpinning of GLI3 expression in other embryonic domains such as craniofacial structures and internal organs remain elusive. Here we demonstrate in a transgenic mice assay the potential of a subset of human/fish conserved non-coding sequences (CNEs) residing within GLI3 intronic intervals to induce reporter gene expression at known regions of endogenous Gli3 transcription in embryonic domains other than central nervous system (CNS) and limbs. Highly specific reporter expression was observed in craniofacial structures, eye, gut, and genitourinary system. Moreover, the comparison of expression patterns directed by these intronic cis-acting regulatory elements in mouse and zebrafish embryos suggests that in accordance with sequence conservation, the target site specificity of a subset of these elements remains preserved among these two lineages. Taken together with our recent investigations, it is proposed here that during vertebrate evolution the Gli3 expression control acquired multiple, independently acting, intronic enhancers for spatiotemporal patterning of CNS, limbs, craniofacial structures and internal organs.

  6. Immunity of international organizations

    CERN Document Server

    Schrijver, Nico

    2015-01-01

    Immunity rules are part and parcel of the law of international organizations. It has long been accepted that international organizations and their staff need to enjoy immunity from the jurisdiction of national courts. However, it is the application of these rules in practice that increasingly causes controversy. Claims against international organizations are brought before national courts by those who allegedly suffer from their activities. These can be both natural and legal persons such as companies. National courts, in particular lower courts, have often been less willing to recognize the immunity of the organization concerned than the organization s founding fathers. Likewise, public opinion and legal writings frequently criticize international organizations for invoking their immunity and for the lack of adequate means of redress for claimants. It is against this background that an international conference was organized at Leiden University in June 2013. A number of highly qualified academics and practit...

  7. Neurology and international organizations.

    Science.gov (United States)

    Mateen, Farrah J

    2013-07-23

    A growing number of international stakeholders are engaged with neurologic diseases. This article provides a brief overview of important international stakeholders in the practice of neurology, including global disease-specific programs, United Nations agencies, governmental agencies with international influence, nongovernmental organizations, international professional organizations, large private donors, private-public partnerships, commercial interests, armed forces, and universities and colleges. The continued engagement of neurologists is essential for the growing number of international organizations that can and should incorporate neurologic disease into their global agendas.

  8. International organizations as orchestrators

    CERN Document Server

    Abbott, Kenneth W

    2015-01-01

    International Organizations as Orchestrators reveals how IOs leverage their limited authority and resources to increase their effectiveness, power, and autonomy from states. By 'orchestrating' intermediaries - including NGOs - IOs can shape and steer global governance without engaging in hard, direct regulation. This volume is organized around a theoretical model that emphasizes voluntary collaboration and support. An outstanding group of scholars investigate the significance of orchestration across key issue areas, including trade, finance, environment and labor, and in leading organizations, including the GEF, G20, WTO, EU, Kimberley Process, UNEP and ILO. The empirical studies find that orchestration is pervasive. They broadly confirm the theoretical hypotheses while providing important new insights, especially that states often welcome IO orchestration as achieving governance without creating strong institutions. This volume changes our understanding of the relationships among IOs, nonstate actors and sta...

  9. Distribution of heavy metals in internal organs and tissues of Korean molluscan shellfish and potential risk to human health.

    Science.gov (United States)

    Mok, Jong Soo; Kwon, Ji Young; Son, Kwang Tae; Choi, Woo Seok; Kim, Poong Ho; Lee, Tae Seek; Kim, Ji Hoe

    2015-09-01

    Molluscan shellfish (gastropods and bivalves) were collected from major fish markets on the Korean coast and analyzed for mercury by direct Hg analyzer and for other metals, such as cadmium, lead, chromium, silver, nickel, copper and zinc, using inductively coupled plasma mass spectrometry. Distribution of heavy metals in muscles, internal organs and whole tissues were determined and a potential risk assessment was conducted to evaluate their hazard for human consumption. Heavy metals were accumulated significantly higher (P organs than in muscles for all species. The mean Cd level, which had the highest level of three hazardous metals (Cd, Pb, and Hg) in all internal-organ samples were above the regulatory limit of Korea and the mean level in whole tissue samples of the selected gastropod species, bay scallop and comb pen shell, exceeded the limit (except in a few cases). The sum of the estimated dietary intake of Cd, Pb and Hg for each part of all tested species accounted for 1.59-16.94, 0.02-0.36, and 0.07-0.16% respectively, of the provisional tolerable daily intake adopted by the Joint FAO/WHO Expert Committee on Food Additives. The hazard index for each part of gastropods and bivalves was below 1.0, however, the maximum HI for internal organs of all analysed species was quite high (0.71). These results suggest that consumption of flesh after removing the internal organs of some molluscan shellfish (all gastropod species, bay scallop and comb pen shell) is a suitable way for reducing Cd exposure.

  10. [Human functioning and disability: exploring the scope of the World Health Organization's international classification].

    Science.gov (United States)

    Sampaio, Rosana Ferreira; Luz, Madel Terezinha

    2009-03-01

    The theoretical discussion on disability is dichotomized according to the medical and social perspectives. The biomedical model focuses on impairment, disease, or physical abnormality and how these factors produce disability. The social approach suggests that the meaning of disability and impairment emerges from specific social and cultural contexts. The WHO created the International Classification of Functioning, Disability and Health (ICF), with a classification system and theoretical model based on the combination of the medical and social models and using a biopsychosocial approach to integrate the health dimensions. Despite the importance and immediacy of the ICF, some concepts were insufficiently detailed and justified and could lead to distinct interpretations. This essay proposes to describe the ICF model and analyze the scope of the biopsychosocial theory for exploring the relational nature of the 'disability' and 'impairment' categories, as well as the universal nature of the WHO proposal. One of the most positive aspects of the ICF is to highlight the interactive nature of disability and the division of the phenomenon into three dimensions, thus demonstrating the degree of complexity in the process of human functioning and disability.

  11. Distribution of heavy metals in muscles and internal organs of Korean cephalopods and crustaceans: risk assessment for human health.

    Science.gov (United States)

    Mok, Jong Soo; Kwon, Ji Young; Son, Kwang Tae; Choi, Woo Seok; Shim, Kil Bo; Lee, Tae Seek; Kim, Ji Hoe

    2014-12-01

    Samples of seven species of cephalopods and crustaceans were collected from major fish markets on the Korean coast and analyzed for mercury (Hg) using a direct Hg analyzer and for the metals cadmium (Cd), lead (Pb), chromium, silver, nickel, copper, and zinc using inductively coupled plasma mass spectrometry. The distributions of heavy metals in muscles, internal organs, and whole tissues were determined, and a risk assessment was conducted to provide information concerning consumer safety. The heavy metals accumulated to higher levels (P organs than in muscles for all species. The mean concentrations of Cd, which had the highest concentrations of the three hazardous metals (Cd, Pb, and Hg), in all internal organs (except those of blue crab) exceeded the regulatory limits set by Korea and the European Union. The Cd concentrations in all whole tissues of squid and octopus (relatively large cephalopods), red snow crab, and snow crab exceeded the European Union limits. The estimated dietary intake of Cd, Pb, and Hg for each part of all species accounted for 1.73 to 130.57%, 0.03 to 0.39%, and 0.93 to 1.67%, respectively, of the provisional tolerable daily intake adopted by the Joint Food and Agriculture Organization and World Health Organization Expert Committee on Food Additives; the highest values were found in internal organs. The hazard index (HI) is recognized as a reasonable parameter for assessing the risk of heavy metal consumption associated with contaminated food. Because of the high HI (>1.0) of the internal organs of cephalopods and the maximum HI for whole tissue of 0.424, consumers eating internal organs or whole tissues of cephalopods could be at risk of high heavy metal exposure. Therefore, the internal organs of relatively large cephalopods and crabs (except blue crab) are unfit for consumption. However, consumption of flesh after removing internal organs is a suitable approach for decreasing exposure to harmful metals.

  12. Integrated endoscopic OCT system and in-vivo images of human internal organs

    Science.gov (United States)

    Sergeev, Alexander M.; Gelikonov, Valentin M.; Gelikonov, Grigory V.; Feldchtein, Felix I.; Kuranov, Roman V.; Gladkova, Natalia D.; Shakhova, Natalia M.; Snopova, Ludmila; Shakhov, Andrei; Kuznetzova, Irina N.; Denisenko, Arkady; Pochinko, Vitaly; Chumakov, Yuri; Almasov, Valentin

    1998-04-01

    First results of endoscopic applications of optical coherence tomography (OCT) for in vivo studies of human mucosa in respiratory, gastrointestinal, urinary and genital tracts are presented. A novel endoscopic OCT (EOCT) system has been created that is based on the integration of a sampling arm of an all-optical-fiber interferometer into standard endoscopic devices using their biopsy channel to transmit low-coherence radiation to investigated tissue. We have studied mucous membranes of esophagus, larynx, stomach, urinary bladder, uterine cervix and endometrium as typical localization for carcinomatous processes. Images of tumor tissues versus healthy tissues have been recorded and analyzed. Violations of well-defined stratified healthy mucosa structure in cancered tissue is distinctly seen by EOCT, thus making this technique promising for early diagnosis of tumors and precise guiding of excisional biopsy.

  13. Making International Organizations More Democratic

    OpenAIRE

    Frey, Bruno S.; Alois Stutzer

    2017-01-01

    World governance today is characterized by international organizations lacking democratic legitimacy and control by the citizens they claim to represent. They are also criticized for being inefficient. This leads to violent protests and to NGOs having great influence. To address these problems, we propose international governance based on the democratic idea of citizen participation: All citizens of the member countries of international organizations have the potential right to participate in...

  14. International organizations before national courts

    CERN Document Server

    Reinisch, August

    2000-01-01

    This book presents a radical, empirical investigation of how national courts "react" to disputes involving international organizations, analyzing in particular whether such organizations should be immune to national jurisdictions. Under the headings "domestic legal personality" and "immunity" of international organizations, some of the issues covered have already been treated in international legal scholarship, mostly in the form of short articles or case notes. This study, however, provides a thorough comparative analysis and the largest compilation of relevant decisions on the subject, making it indispensable for practitioners as well as academics in the field.

  15. Mercury and selenium concentrations in the internal organs of toothed whales and dolphins marketed for human consumption in Japan.

    Science.gov (United States)

    Endo, Tetsuya; Haraguchi, Koichi; Sakata, Masakatsu

    2002-12-02

    Small cetaceans (toothed whales odontoceti and dolphins delphinidae) have been traditionally hunted along the coast of Japan and fresh red meat and blubber, as well as boiled internal organs such as liver, kidney, lung and small intestine, are still being sold for human consumption. We surveyed mercury contamination in boiled liver, kidney and lung products marketed in Japan between 1999-2001. The average +/- S.D. of total mercury (T-Hg) was 370 +/- 525 (range: 7.60 approximately 1980, n = 26) microg/g in liver, 40.5 +/- 48.5 (7.30-95.1, n = 15) microg/g in kidney and 42.8 +/- 43.8 (2.10-79.6, n = 23) microg/g in lung. A high correlation was observed between T-Hg and selenium (Se) concentrations in these organs, supporting the formation of a Hg-Se complex. The formation of a Hg-Se complex probably contribute to the detoxification of Hg for cetaceans and allows a very large accumulation of Hg in livers. The provisional permitted level of T-Hg in marine foods set by the Japanese Ministry of Health and Welfare is 0.4 microg/ g, and the provisional permitted weekly intake (PTWI) set by WHO is 5 microg/kg bw/week. The maximal T-Hg detected in boiled liver (1,980 microg/g) exceeds the permitted level by approximately 5,000 times and the consumption of only 0.15 g of liver exceeds the PTWI of 60 kg of body weight of the consumer, suggesting the possibility of an acute intoxication by T-Hg even after a single consumption of the product.

  16. International Organizations and Organizational Fields

    DEFF Research Database (Denmark)

    Vetterlein, Antje; Moschella, Manuela

    2014-01-01

    The purpose of this paper is to account for varieties of organizational change. In particular, we contend that in order to explain change in international organizations (IOs) we cannot simply dichotomize between change and the lack thereof. Rather, change is best conceptualized as made up of two ...

  17. International human resources management challenges and changes

    CERN Document Server

    2015-01-01

    This book covers the issues related to human resource management (HRM) in an international context. It gives perspectives and future direction in International HRM research. The chapters explore the models, tools and processes used by international organizations in order to assist international managers to better face the challenges and changes in HRM. It is suitable to HR managers, engineers, entrepreneurs, practitioners, academics and researchers in the field.

  18. Standardization of human IL-29 (IFN-λ1): establishment of a World Health Organization international reference reagent for IL-29 (IFN-λ1).

    Science.gov (United States)

    Meager, Anthony; Heath, Alan; Dilger, Paula; Zoon, Kathryn; Wadhwa, Meenu

    2014-11-01

    Human interleukin-29 (IL-29), a helical cytokine with interferon-like activities, is currently being developed as a clinical biotherapeutic to treat chronic hepatitis C infection and some cancers. As such, the World Health Organization (WHO) has recognized a need for biological standardization of IL-29 and the establishment of an internationally available reference reagent of IL-29. In order to accomplish this, an international collaborative study that evaluates WHO candidate reference reagents of IL-29 was instigated by the National Institute for Biological Standards and Control (NIBSC) in 2010 and was carried out in the succeeding year. Two preparations of human sequence recombinant IL-29, one expressed in murine NS0 cells and the other in Escherichia coli, were formulated and lyophilized at NIBSC before evaluation in the collaborative study for their suitability to serve as a reference reagent. The preparations were tested by 6 laboratories from 4 countries using in vitro bioassays and also evaluated for thermal stability within the NIBSC laboratory. On the basis of the results of the collaborative study, both preparations, 07/212 (NS0-derived) and 10/176 (E. coli-derived) were judged sufficiently active and stable to serve as a reference reagent. However, since IL-29 produced in E. coli is in development for clinical applications, it was recommended that the preparation coded 10/176 be established as the WHO international reference reagent for human IL-29. This recommendation was accepted, and the IL-29 preparation coded 10/176 was formally established by the WHO ECBS at its meeting in October 2012 as the WHO international reference reagent for IL-29 with an assigned unitage of 5,000 reference units per ampoule.

  19. Critical Dose of Internal Organs Internal Exposure - 13471

    Energy Technology Data Exchange (ETDEWEB)

    Grigoryan, G.; Amirjanyan, A. [Nuclear and Radiation Safety Centre (Armenia); Grigoryan, N. [Yerevan State Medical University 4Tigran Mets,375010 Yerevan (Armenia)

    2013-07-01

    The health threat posed by radionuclides has stimulated increased efforts to developed characterization on the biological behavior of radionuclides in humans in all ages. In an effort motivated largely by the Chernobyl nuclear accident, the International Commission on Radiological Protection (ICRP) is assembling a set of age specific biokinetic models for environmentally important radioelements. Radioactive substances in the air, mainly through the respiratory system and digestive tract, is inside the body. Radioactive substances are unevenly distributed in various organs and tissues. Therefore, the degree of damage will depend not only on the dose of radiation have but also on the critical organ, which is the most accumulation of radioactive substances, which leads to the defeat of the entire human body. The main objective of radiation protection, to avoid exceeding the maximum permissible doses of external and internal exposure of a person to prevent the physical and genetic damage people. The maximum tolerated dose (MTD) of radiation is called a dose of radiation a person in uniform getting her for 50 years does not cause changes in the health of the exposed individual and his progeny. The following classification of critical organs, depending on the category of exposure on their degree of sensitivity to radiation: First group: the whole body, gonads and red bone marrow; Second group: muscle, fat, liver, kidney, spleen, gastrointestinal tract, lungs and lens of the eye; The third group: bone, thyroid and skin; Fourth group: the hands, forearms, feet. MTD exposure whole body, gonads and bone marrow represent the maximum exposures (5 rem per year) experienced by people in their normal activities. The purpose of this article is intended dose received from various internal organs of the radionuclides that may enter the body by inhalation, and gastrointestinal tract. The biokinetic model describes the time dependent distribution and excretion of different

  20. Towards International Humanism

    Science.gov (United States)

    Huxley, Julian

    1971-01-01

    The basic task before the educational profession today is to study and understand the evolutionary-humanist revolution, to follow up its educational implications; and to enable as many as possible of the world's growing minds to be illuminated by its new vision of human destiny. (Author/JB)

  1. The Development of Customary International Law by International Organizations

    DEFF Research Database (Denmark)

    Odermatt, Jed

    2017-01-01

    discussion about whether and how the practice of international organizations as such may contribute to the development of customary international law. This contribution discusses the organization that is the most capable of contributing to the development of customary international law in its own right......: the European Union. Using examples from the EU’s treaty practice and from the Court of Justice of the EU, it argues that the Union does not simply represent the collective will of its Member States, but also is capable of contributing to customary international law in its own right.......In his Fourth Report on the Identification of Customary International Law (2016), Special Rapporteur Michael Wood confirmed that ‘[i]n certain cases, the practice of international organizations also contributes to the expression, or creation, of rules of customary international law...

  2. APECTS REGARDING INTERNAL AUDIT PLANNING IN THE NONPROFIT ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    DANIELA VITAN

    2015-04-01

    Full Text Available Our study refers to the planning of internal audit within the nonprofit organizations. The starting point is the hypothesis that planning of internal audit in nonprofit organizations is printed by their specific features and we want to highlight the way this influence occurs, which are the specific objectives that have to be pursued within the internal audit. During our research, in order to test the hypothesis we studied the national legal regulations, the specific literature of the field and we realized a practical documentation by consulting the internal audit guides of a foreign nonprofit organization. Our study reveals that in this area the legislation in force refers only to the compulsiveness of developing the internal audit activity in some specific categories of nonprofit organizations, without referring to the specific rules of organizing this activity within the nonprofit organizations. The national literature of the field is poor, but at the international level, the authors have concerns regarding the internal audit within the nonprofits. From a practical point of view, we emphasized the specific aspects of nonprofit organizations followed while planning internal audit regarding the financial system, budgetary system, internal control system, financing sources and human resources. We concluded that each audited field is influenced by the specific features of non-profit organizations within them. These features must be taken into account when planning the audit and drawing up the specific procedures within the nonprofits in order to add value to the audited information within internal audit engagement.

  3. International multicenter opinion study: administrative personnel from Spanish and Mexican health centers faced with human organ donation for transplantation.

    Science.gov (United States)

    Ríos, A; López-Navas, A; Ayala-García, M A; Sebastián, M J; Martínez-Alarcón, L; González, B; Ramírez, E J; Muñoz, G; Camacho, A; Rodríguez, J S; Martínez, M A; Nieto, A; Ramis, G; Ramírez, P; Parrilla, P

    2010-10-01

    Administrative personnel from healthcare centers are an important opinion group given their direct relationship to patients and the general public. The objective of this study was to analyze the attitudes of administrative personnel in Spanish and Mexican healthcare centers toward various kinds of donation. A random selection of 418 administrative staff from 32 primary care centers and 9 hospitals in Spain and Mexico ("Proyecto Donante, Murcia") used a validated questionnaire to explore attitudes. Most (76%) respondents favored deceased donation. Mexican workers had the most favorable attitude (Ppersonal experience of organ donation and transplantation (ODT), attitude toward living donation, attitude toward the donation of a family member's organs, discussion of ODT, partner's attitude toward ODT, participation in pro-social activities, and variables related to attitudes toward the body. Most respondents (89%) favored related living kidney donation (LKD) and 87% favored living liver donation (LLD). Mexican respondents showed the most favorable attitudes (Ppersonal experience of ODT, belief that a transplant is needed, willingness to accept a living organ, family discussion about ODT, partner's attitude about the matter, and respondent's awareness of the view of his or her religion toward ODT. Attitudes toward deceased organ donation were not favorable among administrative personnel from Spanish compared with Mexican centers, although attitudes toward LKD and LLD were favorable in both countries. Copyright © 2010 Elsevier Inc. All rights reserved.

  4. The International Human Epigenome Consortium

    DEFF Research Database (Denmark)

    Stunnenberg, Hendrik G; Hirst, Martin

    2016-01-01

    The International Human Epigenome Consortium (IHEC) coordinates the generation of a catalog of high-resolution reference epigenomes of major primary human cell types. The studies now presented (see the Cell Press IHEC web portal at http://www.cell.com/consortium/IHEC) highlight the coordinated ac...... achievements of IHEC teams to gather and interpret comprehensive epigenomic datasets to gain insights in the epigenetic control of cell states relevant for human health and disease. PAPERCLIP.......The International Human Epigenome Consortium (IHEC) coordinates the generation of a catalog of high-resolution reference epigenomes of major primary human cell types. The studies now presented (see the Cell Press IHEC web portal at http://www.cell.com/consortium/IHEC) highlight the coordinated...

  5. Child organ trafficking: global reality and inadequate international response.

    Science.gov (United States)

    Bagheri, Alireza

    2016-06-01

    In organ transplantation, the demand for human organs has grown far faster than the supply of organs. This has opened the door for illegal organ trade and trafficking including from children. Organized crime groups and individual organ brokers exploit the situation and, as a result, black markets are becoming more numerous and organized organ trafficking is expanding worldwide. While underprivileged and vulnerable men and women in developing countries are a major source of trafficked organs, and may themselves be trafficked for the purpose of illegal organ removal and trade, children are at especial risk of exploitation. With the confirmed cases of children being trafficked for their organs, child organ trafficking, which once called a "modern urban legend", is a sad reality in today's world. By presenting a global picture of child organ trafficking, this paper emphasizes that child organ trafficking is no longer a myth but a reality which has to be addressed. It argues that the international efforts against organ trafficking and trafficking in human beings for organ removal have failed to address child organ trafficking adequately. This chapter suggests that more orchestrated international collaboration as well as development of preventive measure and legally binding documents are needed to fight child organ trafficking and to support its victims.

  6. International Organizations and Environmental Protection

    DEFF Research Database (Denmark)

    Meyer, Jan-Henrik; Kaiser, Wolfram

    of sustainable development.” · Sara Lorenzini, University of Trento Wolfram Kaiser is Professor of European Studies at the University of Portsmouth and Visiting Professor at the College of Europe in Bruges. His recent publications include Writing the Rules for Europe: Experts, Cartels, and International...

  7. Regional International Organizations as Conflict Managers: The ...

    African Journals Online (AJOL)

    the roles of regional international organizations in conflict management. With ... organizations have assumed increasingly varied, and in some cases primary roles in conflict ... communications, financial resources and chain command. The result ... North Atlantic Treaty Organization (NATO) issued a declaration on terrorism.

  8. ASPECTS ON THE INTERNATIONAL LEGAL PERSONALITY OF INTERNATIONAL ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    NICOLAE PURDA

    2012-05-01

    Full Text Available An international organization is an association of states, holder of rights and duties which it acquires by the will of the founding states and which acts as an entity which is distinct and independent from the states that form it. The constituent instrument of the organization proclaims the establishment of such, as well as its character of being a subject of international law, but at the same time it delimitates the domain in which the international legal personality can manifest and also the content of its capacity.

  9. United Nations and Other International Organizations.

    Science.gov (United States)

    Negaard, Chere; Van Fossen, Michael

    1993-01-01

    Presents an annotated bibliography of 124 items published by the United Nations and 12 other international organizations in 1992-93. Themes addressed include agriculture, development, poverty eradication, trade, privatization, peace, conflict resolution, women's equality, and health issues. (LRW)

  10. Future Performance Trend Indicators: A Current Value Approach to Human Resources Accounting. Report II: Internal Consistencies and Relationships to Performance in Organization VI. Technical Report.

    Science.gov (United States)

    Pecorella, Patricia A.; Bowers, David G.

    Conventional accounting systems provide no indication as to what conditions and events lead to reported outcomes, since they traditionally do not include measurements of the human organization and its relationship to events at the outcome stage. Human resources accounting is used to measure these additional types of data. This research is…

  11. International Organization and Peacekeeping. Teacher's Guide.

    Science.gov (United States)

    Freeman, Robert E.

    The teaching guide for secondary students focuses on the structure, authority, and decision making procedures of international organizations and their ability to keep peace. Students participate in an exercise for predicting how present organizations can handle peace-threatening situations and how they can be designed to improve their peacekeeping…

  12. Specialized Rules of Treaty Interpretation: International Organizations

    NARCIS (Netherlands)

    Brölmann, C.; Hollis, D.B.

    2012-01-01

    This paper addresses treaty interpretation in the context of international organizations, with particular attention to interpreting the founding or constitutive treaties of organizations. That not all interpretive rules are the same for all treaties is a well-tried proposition (see e.g. Arnold McNai

  13. Budgeting-Based Organization of Internal Control

    Science.gov (United States)

    Rogulenko, Tatiana; Ponomareva, Svetlana; Bodiaco, Anna; Mironenko, Valentina; Zelenov, Vladimir

    2016-01-01

    The article suggests methodical approaches to the budgeting-based organization of internal control, determines the tasks and subtasks of control that consist in the construction of an efficient system for the making, implementation, control, and analysis of managerial decisions. The organization of responsibility centers by means of implementing…

  14. International energy: Research organizations, 1986--1990

    Energy Technology Data Exchange (ETDEWEB)

    Hendricks, P.; Jordan, S. (eds.) (USDOE Office of Scientific and Technical Information, Oak Ridge, TN (USA))

    1991-03-01

    The International Energy: Research Organizations publication contains the standardized names of energy research organizations used in energy information databases. Involved in this cooperative task are (1) the technical staff of the USDOE Office of Scientific and Technical Information (OSTI) in cooperation with the member countries of the Energy Technology Data Exchange (ETDE) and (2) the International Nuclear Information System (INIS). This publication identifies current organizations doing research in all energy fields, standardizes the format for recording these organization names in bibliographic citations, assigns a numeric code to facilitate data entry, and identifies report number prefixes assigned by these organizations. These research organization names may be used in searching the databases Energy Science Technology'' on DIALOG and Energy'' on STN International. These organization names are also used in USDOE databases on the Integrated Technical Information System. Research organizations active in the past five years, as indicated by database records, were identified to form this publication. This directory includes approximately 34,000 organizations that reported energy-related literature from 1986 to 1990 and updates the DOE Energy Data Base: Corporate Author Entries.

  15. International energy: Research organizations, 1986 - 1990

    Science.gov (United States)

    Hendricks, P.; Jordan, S.

    1991-03-01

    The International Energy: Research Organizations publication contains the standardized names of energy research organizations used in energy information databases. Involved in this cooperative task are (1) the technical staff of the USDOE Office of Scientific and Technical Information (OSTI) in cooperation with the member countries of the Energy Technology Data Exchange (ETDE), and (2) the International Nuclear Information System (INIS). This publication identifies current organizations doing research in all energy fields, standardizes the format for recording these organization names in bibliographic citations, assigns a numeric code to facilitate data entry, and identifies report number prefixes assigned by these organizations. These research organization names may be used in searching the databases Energy Science and Technology on DIALOG and Energy on STN International. These organization names are also used in USDOE databases on the Integrated Technical Information System. Research organizations active in the past five years, as indicated by database records, were identified to form this publication. This directory includes approximately 34,000 organizations that reported energy-related literature from 1986 to 1990 and updates the DOE Energy Data Base: Corporate Author Entries.

  16. 22 CFR 140.7 - Multilateral institutions and international organizations.

    Science.gov (United States)

    2010-04-01

    ... TO DRUG TRAFFICKERS Enforcement § 140.7 Multilateral institutions and international organizations. Assistance provided to or through multilateral institutions or international organizations is subject to this... that a recipient multilateral institution or international organization may be or may have...

  17. TRANSNATIONAL ORGANIZED CRIME. AN (INTERNATIONAL SECURITY PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Ionel Stoica

    2016-10-01

    Full Text Available For the past two decades organized crime has become a transnational phenomenon, and its impact is still far from being fully known and understood by common people. Its forms of manifestation, whether explicit, or subtle, are permanently evolving and adapting. As a result, its interference with the activities from the legal area makes it difficult to identify and counteract. After a long period of time when it was more a peripheral phenomenon, current transnational organized crime tends to become a major danger to the political, social and economic stability of the states. Through its nature and goals, as well as through the complexity of its forms of manifestation, transnational organized crime represents a major challenge for the state and nonstate organizations that deal with national and international security This paper focuses on the phenomenon starting from some of the most influent theories in international relations, presents the current features of transnational organized criminal groups and analyzes the causes and the favoring factors of the phenomenon, as well as the impact of the phenomenon upon national and international security at political, economic-financial and military level. The approach is an interdisciplinary one and also covers the nexus between transnational organized crime and international terrorism.

  18. An international organization for remote sensing

    Science.gov (United States)

    Helm, Neil R.; Edelson, Burton I.

    1991-01-01

    A recommendation is presented for the formation of a new commercially oriented international organization to acquire or develop, coordinate or manage, the space and ground segments for a global operational satellite system to furnish the basic data for remote sensing and meteorological, land, and sea resource applications. The growing numbers of remote sensing programs are examined and possible ways of reducing redundant efforts and improving the coordination and distribution of these global efforts are discussed. This proposed remote sensing organization could play an important role in international cooperation and the distribution of scientific, commercial, and public good data.

  19. Human Rights: Dialogue and International Cooperation

    Institute of Scientific and Technical Information of China (English)

    王水霞; 孟保林

    2007-01-01

    @@ Dialogue is a major form of international cooperation on human rights issues. It is also instrumental in settling human rights disputes between nations. In this age of globalization, extensive global dialogues on human rights serve to deepen mutual understanding between nations, speed up the formation of international norms governing human rights, and hasten the advent of a harmonious world.

  20. Identities of states in international organizations

    NARCIS (Netherlands)

    Wessel, Ramses A.; Dekker, I.F.; Dekker, Ige F.

    2015-01-01

    In academic debates on the responsibility of international organizations and their member States the different identities of States play a crucial role. However, apart from the difficulty to clearly separate ‘State’ and ‘member State’ identities, it is even more complex to distinguish between the

  1. Identities of states in international organizations

    NARCIS (Netherlands)

    Wessel, Ramses A.; Dekker, Ige F.

    2015-01-01

    In academic debates on the responsibility of international organizations and their member States the different identities of States play a crucial role. However, apart from the difficulty to clearly separate ‘State’ and ‘member State’ identities, it is even more complex to distinguish between the di

  2. US Human Rights Conduct and International Legitimacy

    DEFF Research Database (Denmark)

    Keating, Vincent Charles

    Did the Bush administration fundamentally harm the international human rights system through its rejection of human rights norms? This is the central question explored within US Human Rights Conduct and International Legitimacy, which analyses the practices of legitimacy between the Bush...... nations have followed in America's footsteps, and that the Bush administration's deviation from international norms has served to reaffirm worldwide commitment to human rights....

  3. Immunity and privilege of international organizations in Kosovo

    Directory of Open Access Journals (Sweden)

    Arif Riza

    2016-11-01

    Full Text Available To speak for the Diplomatic Law (Immunities and Privileges in International Organizations, first, this topic briefly describes the international organizations, what are they, as established, as extinct, and finally, as a shared international organizations. They are not subject of this paper, but Immunity and Privileges in International Organizations are. This paper gives an overview of the history of the immunity and privileges in international organizations, conventions, laws of the country regarding Immunities and Privileges, where the seat of the International Organization, Immunities and privileges of diplomatic representatives in international organizations, Immunities and privileges of representatives of international organizations in the state where the seat of the Organization, immunity and privileges of members of the family, diplomatic representatives International Organizations, Immunities and Privileges in the European Union, the difference between the immunity and privileges of international organizations, and Immunity and Privileges between states. This paper analyzes also the immunity and inviolability of buildings of International Organizations, immunity and inviolability of the archives of international organizations, the immunity and privileges of goods to international organizations, the release from the obligation of tax payments, the release from the provision of the diplomatic staff of International Organizations, etc. However, the paper includes charts, respectively, some official data from countries where the headquarters of international organizations are situated and gives an overview of the number of international governmental and nongovernmental organizations.

  4. Leadership in a Humane Organization

    Science.gov (United States)

    Dimitrov, Danielle

    2015-01-01

    Purpose: The purpose of this paper is to explore the way leadership influences an organization to become humane through its features and behaviors; as well as the organizational circumstances in which humane leadership can be nurtured. The first empirical case study, in the fields of Human Resource Development (HRD) and hospitality management, to…

  5. Leadership in a Humane Organization

    Science.gov (United States)

    Dimitrov, Danielle

    2015-01-01

    Purpose: The purpose of this paper is to explore the way leadership influences an organization to become humane through its features and behaviors; as well as the organizational circumstances in which humane leadership can be nurtured. The first empirical case study, in the fields of Human Resource Development (HRD) and hospitality management, to…

  6. International Organization for Standardization (ISO) 15189.

    Science.gov (United States)

    Schneider, Frank; Maurer, Caroline; Friedberg, Richard C

    2017-09-01

    The College of American Pathologists (CAP) offers a suite of laboratory accreditation programs, including one specific to accreditation to the international organization for standardization (ISO) 15189 standard for quality management specific to medical laboratories. CAP leaders offer an overview of ISO 15189 including its components, internal audits, occurrence management, document control, and risk management. The authors provide a comparison of its own ISO 15189 program, CAP 15189, to the CAP Laboratory Accreditation Program. The authors conclude with why laboratories should use ISO 15189. © The Korean Society for Laboratory Medicine.

  7. Human organ markets and inherent human dignity.

    Science.gov (United States)

    MacKellar, Calum

    2014-01-01

    It has been suggested that human organs should be bought and sold on a regulated market as any other material property belongingto an individual. This would have the advantage of both addressing the grave shortage of organs available for transplantation and respecting the freedom of individuals to choose to do whatever they want with their body parts. The old arguments against such a market in human organs are, therefore, being brought back into question. The article examines the different arguments both in favour and against the sale of human organs. It concludes that the body and any of its elements is a full expression of the whole person. As such, they cannot have a price if the individual is to retain his or her full inherent dignity and if society is to retain and protect this very important concept.

  8. Immunity and privilege of international organizations in Kosovo

    OpenAIRE

    Arif Riza

    2016-01-01

    To speak for the Diplomatic Law (Immunities and Privileges) in International Organizations, first, this topic briefly describes the international organizations, what are they, as established, as extinct, and finally, as a shared international organizations. They are not subject of this paper, but Immunity and Privileges in International Organizations are. This paper gives an overview of the history of the immunity and privileges in international organizations, conventions, laws of the country...

  9. Integrating internal communications, human resource management and marketing concepts into the new internal marketing philosophy

    OpenAIRE

    Dubravka Sinčić; Nina Pološki Vokić

    2007-01-01

    Successful companies attach great importance to human resource management and internal communications, because they are aware of the value of those activities and of strategic advantage they can bring to the organization. They should also realize that it is necessary to live internal marketing philosophy, if they stream to offer quality products and services to both markets: internal and external. The idea of satisfied employees for the benefit of satisfied customers is accepted a...

  10. International Organizations as Producers of Development Goods

    Directory of Open Access Journals (Sweden)

    Fabio Daneri

    2015-07-01

    Full Text Available International organizations can be considered as providers of “development goods”, which contribute to the process of development of recipient countries. This phenomenon gives birth to a particular market, with its own characteristics, which is very similar to an oligopoly due to the high requirements needed for the birth of an international organization. This paper will analyze the characteristics of this particular market, where goods are financed by developed countries and consumed by emerging countries. Given these peculiar characteristics, this market is characterized by several particular features, the mainly being a suboptimal level of finance, given that only a part of the public opinion in developed countries is concerned about the economics of emerging countries. In addition to this phenomena, it must be added that several actors are involved, being them individuals, ministries, NGOs, private companies, so that everybody tend to benefit by the intermediation of the resources. It should be highlighted that, for the time being, it is very difficult to modify the characteristics of this market, which tends to have stable and self-perpetuating features.

  11. 22 CFR 41.24 - International organization aliens.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false International organization aliens. 41.24... aliens. (a) Definition of international organization. “International organization” means: (1) Any public...)(27)(I), INTELSAT or any successor or separated entity thereof. (b) Aliens coming to international...

  12. 5 CFR 870.509 - Transfers to international organizations.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Transfers to international organizations. 870.509 Section 870.509 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL... Transfers to international organizations. An employee transferred to an international organization...

  13. 5 CFR 352.304 - International organizations covered.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false International organizations covered. 352... REEMPLOYMENT RIGHTS Detail and Transfer of Federal Employees to International Organizations § 352.304 International organizations covered. (a) An agency may detail or transfer an employee under this...

  14. Vomeronasal organ and human pheromones.

    Science.gov (United States)

    Trotier, D

    2011-09-01

    For many organisms, pheromonal communication is of particular importance in managing various aspects of reproduction. In tetrapods, the vomeronasal (Jacobson's) organ specializes in detecting pheromones in biological substrates of congeners. This information triggers behavioral changes associated, in the case of certain pheromones, with neuroendocrine correlates. In human embryos, the organ develops and the nerve fibers constitute a substrate for the migration of GnRH-secreting cells from the olfactory placode toward the hypothalamus. After this essential step for subsequent secretion of sex hormones by the anterior hypophysis, the organ regresses and the neural connections disappear. The vomeronasal cavities can still be observed by endoscopy in some adults, but they lack sensory neurons and nerve fibers. The genes which code for vomeronasal receptor proteins and the specific ionic channels involved in the transduction process are mutated and nonfunctional in humans. In addition, no accessory olfactory bulbs, which receive information from the vomeronasal receptor cells, are found. The vomeronasal sensory function is thus nonoperational in humans. Nevertheless, several steroids are considered to be putative human pheromones; some activate the anterior hypothalamus, but the effects observed are not comparable to those in other mammals. The signaling process (by neuronal detection and transmission to the brain or by systemic effect) remains to be clearly elucidated.

  15. Bioethics and international human rights.

    Science.gov (United States)

    Thomasma, D C

    1997-01-01

    Noting how the spread of medical technology is creating clashes with traditional values and within cultures, the author addresses the clash between Western rights-based incentives, as used by the United Nations to guarantee respect for life and dignity, and communitarian traditions. He proposes a mean between wholesale cultural relativism and international absolutism.

  16. Progress in the international protection of human rights.

    Science.gov (United States)

    Suter, Keith

    2002-01-01

    Great progress has been made in the international protection of human rights since 10 December 1948 (when the United Nations General Assembly adopted the Universal Declaration of Human Rights). Amidst the doom and gloom of the media's reporting of current affairs, it is easy to overlook this progress. This article provides a definition of 'human rights' and examines early human rights campaigns. It then considers the areas of progress: human rights are now part of the international political vocabulary, there is a recognition that respect for human rights can assist a country's economic and social development, there has been a growth of human rights treaties and techniques and non-governmental organizations (NGOs) see protecting human rights as a major activity. State sovereignty has been eroded as national governments are being held accountable to the international community for their human rights policies. A new challenge is to ensure respect for human rights by non-state entities, such as transnational corporations. The growing culture of international protection of human rights is here to stay. This is not a reason for complacency, but it is a sign of hope.

  17. International Program and Local Organizing Committees

    Science.gov (United States)

    2012-12-01

    International Program Committee Dionisio Bermejo (Spain) Roman Ciurylo (Poland) Elisabeth Dalimier (France) Alexander Devdariani (Russia) Milan S Dimitrijevic (Serbia) Robert Gamache (USA) Marco A Gigosos (Spain) Motoshi Goto (Japan) Magnus Gustafsson (Sweden) Jean-Michel Hartmann (France) Carlos Iglesias (USA) John Kielkopf (USA) John C Lewis (Canada) Valery Lisitsa (Russia) Eugene Oks (USA) Christian G Parigger (USA) Gillian Peach (UK) Adriana Predoi-Cross (Canada) Roland Stamm (Germany) Local Organizing Committee Nikolay G Skvortsov (Chair, St Petersburg State University) Evgenii B Aleksandrov (Ioffe Physico-Technical Institute, St Petersburg) Vadim A Alekseev (Scientific Secretary, St Petersburg State University) Sergey F Boureiko (St.Petersburg State University) Yury N Gnedin (Pulkovo Observatory, St Petersburg) Alexander Z Devdariani (Deputy Chair, St Petersburg State University) Alexander P Kouzov (Deputy Chair, St Petersburg State University) Nikolay A Timofeev (St Petersburg State University)

  18. International law, human rights and HIV/AIDS.

    OpenAIRE

    Patterson, David; London, Leslie

    2002-01-01

    This article explores the relevance of international human rights law in the response to the HIV/AIDS epidemic at national and international levels. Public health advocates can use arguments based on this body of law to promote responses to HIV/AIDS that reflect sound public health principles and documented best practice. Development assistance is increasingly linked to rights-based approaches, such as participatory processes, and strategic alliances between health professionals, organization...

  19. International Perspective on Teaching Human Sexuality

    Science.gov (United States)

    Wylie, Kevan; Weerakoon, Patricia

    2010-01-01

    Objective: The authors outline international training programs in human sexuality. Methods: The authors reviewed the international literature and Internet resources to identify key training opportunities and curricula, with particular emphasis on training opportunities for psychiatrists. Results: The authors outline key resources and training…

  20. The Human Rights Approach to Education in International Organisations

    Science.gov (United States)

    Hufner, Klaus

    2011-01-01

    In this article, the work of three international governmental organisations (IGOs) dealing with human rights will be discussed, namely the United Nations Educational, Scientific and Cultural Organization (UNESCO), the United Nations Children's Fund (UNICEF) and the Council of Europe (CoE). In the first section, the main characteristics of the…

  1. The Human Rights Approach to Education in International Organisations

    Science.gov (United States)

    Hufner, Klaus

    2011-01-01

    In this article, the work of three international governmental organisations (IGOs) dealing with human rights will be discussed, namely the United Nations Educational, Scientific and Cultural Organization (UNESCO), the United Nations Children's Fund (UNICEF) and the Council of Europe (CoE). In the first section, the main characteristics of the…

  2. Legal Personality of Inter-Governmental International Organizations

    Directory of Open Access Journals (Sweden)

    Cristian Jura

    2013-05-01

    Full Text Available Upon the incorporation of an inter-governmental international organization, the states assign to such entities some of their powers, based on which the organization will promote the collective interests of its members. Thus, the international organizations perform some public functions based on which they enter in contact with other entities of international order, such as different states or other organizations. Manifesting as such, they acquire their own legal personality, distinct from that of the states forming it, and which it is opposable erga omnes. The scope of such article is to examine the legal personality of inter-governmental international organizations providing one apprehends the limits of their juridical personality. In the achievement of such objective, I have developed both the internal juridical personality and the international juridical personality of international organizations, recording the manner of manifestation of such legal personality.

  3. Human dignity according to international instruments on human rights

    Directory of Open Access Journals (Sweden)

    José Pablo Alzina de Aguilar

    2011-01-01

    Full Text Available According to international instruments on human rights, the dignity of the human person is the foundation of human rights, and both human dignity and human rights are inherent to the human being, universal and inviolable. This understanding of human dignity is not a fruitless truism, but the solid foundation on which to build a world community under the rule of the new ius gentium: the International Law for Humankind. Moreover, it is the clue to answer many questions raised by the new world of globalization and of the exponential growth of international rules.Consequently, there is a need to a common doctrine on a notion of human dignity which will allow the implementation and adjudication of the aforementioned instruments, at the service of the human person and in conformity with the juridical conscience which they reflect. Philosophy of Law concepts which can be traced back to Aristotle provide that notion. According to these concepts, the demanding nature of “human dignity” sustains the notion of “legal personhood”, and both notions pertain to the realm of Law and Right, not of Morale and Values. Thus, human dignity and human rights are and must be, respectively, a basic principle and a necessary part of any Law system, including international law

  4. World Energy Data System (WENDS). Volume V. International organization data

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-06-01

    The World Energy Data System contains organized data on those countries and international organizations that may have critical impact on the world energy scene. WENDS has acquired and organized information on the following energy-related organizations: Asian Development Bank; European Economic Community; Inter-American Development Bank; International Atomic Energy Agency; International Energy Agency; Nuclear Energy Agency; United Nations; and World Bank. Within each organizational grouping most of the following topics are addressed: organization background, government background, energy background (energy policy and objectives), energy research and development activities, and international activities.

  5. International law, human rights and HIV/AIDS.

    Science.gov (United States)

    Patterson, David; London, Leslie

    2002-01-01

    This article explores the relevance of international human rights law in the response to the HIV/AIDS epidemic at national and international levels. Public health advocates can use arguments based on this body of law to promote responses to HIV/AIDS that reflect sound public health principles and documented best practice. Development assistance is increasingly linked to rights-based approaches, such as participatory processes, and strategic alliances between health professionals, organizations of people living with HIV/AIDS, and affected communities. Legal and human rights advocacy strategies are increasingly productive and necessary. PMID:12571725

  6. International human resource management and organizational learning

    Directory of Open Access Journals (Sweden)

    Bogićević-Milikić Biljana

    2005-01-01

    Full Text Available Global companies are pressed by the need to simultaneously manage globally since they consider the whole world as their own market, and locally, because the global market consists of various different and weakly connected market segments. The need to be global and local at the same time presents, perhaps the most important challenge for management of global companies in 21st century. Searching this balance presents also an important challenge for human resource management (HRM, regarding the ways of accomplishing it. HRM is expected to contribute to achievement of global competitive advantage worldwide efficiency, local responsiveness, as well as transfer of learning within global organizations. The transfer of learning gains on its importance as many authors see it as the main motive of establishing global companies. However, regardless of recognized significance of organizational learning for global companies, international HRM literature simply lacks studies related to transfer of learning, recommendations about how to develop this organizational ability, how to improve it and measure, and how to provide permanency of the learning process. Therefore, the aim of this paper is through reviewing the relevant literature, to shed light on different aspects of the responsiveness-integration paradigm and its implications on the transfer of learning in global companies.

  7. Endocrine Disruptors: An Evolving Health Concern in International Organizations

    Directory of Open Access Journals (Sweden)

    Iris Borowy

    2016-12-01

    Full Text Available Endocrine disrupting chemicals (EDCs are compounds believed to mimic hormones in animal and human bodies and which are thought therefore to be a potential threat to health. Agencies including the European Commission, the International Labour Office (ILO, the Food and Agriculture Organization (FAO, the World Health Organization (WHO, the UN Environment Programme (UNEP each had some responsibility for chemicals in the wider environment over the last five decades. Despite this, the issue of how far the use of EDCs represents a threat to public health remains contested and policy remains uncertain. This article aims to examine the response of IHOs to the growing perception that EDCs can have negative health impacts by disentangling the various agendas and actors involved.

  8. Institutionalising Human Governance Determinant: Steering Organizations towards Sustainability

    Science.gov (United States)

    Muhamad Hanapiyah, Zulkefli; Daud, Salina; Abdullah, Wan Mohammad Taufik Wan

    2016-03-01

    This paper discusses past researches on human governance elements. Eight elements of human governance are proposed in this paper: leadership, integrity, religiosity, spirituality, culture, recruitment, training and internal control policy. Empirical study shall be conducted in the future study to confirm the eight elements of human governance proposed in this paper. It is expected that these elements may enhance the human governance practice in the organizations.

  9. Human rights violations in organ procurement practice in China.

    Science.gov (United States)

    Paul, Norbert W; Caplan, Arthur; Shapiro, Michael E; Els, Charl; Allison, Kirk C; Li, Huige

    2017-02-08

    Over 90% of the organs transplanted in China before 2010 were procured from prisoners. Although Chinese officials announced in December 2014 that the country would completely cease using organs harvested from prisoners, no regulatory adjustments or changes in China's organ donation laws followed. As a result, the use of prisoner organs remains legal in China if consent is obtained. We have collected and analysed available evidence on human rights violations in the organ procurement practice in China. We demonstrate that the practice not only violates international ethics standards, it is also associated with a large scale neglect of fundamental human rights. This includes organ procurement without consent from prisoners or their families as well as procurement of organs from incompletely executed, still-living prisoners. The human rights critique of these practices will also address the specific situatedness of prisoners, often conditioned and traumatized by a cascade of human rights abuses in judicial structures. To end the unethical practice and the abuse associated with it, we suggest to inextricably bind the use of human organs procured in the Chinese transplant system to enacting Chinese legislation prohibiting the use of organs from executed prisoners and making explicit rules for law enforcement. Other than that, the international community must cease to abet the continuation of the present system by demanding an authoritative ban on the use of organs from executed Chinese prisoners.

  10. Human genetics: international projects and personalized medicine.

    Science.gov (United States)

    Apellaniz-Ruiz, Maria; Gallego, Cristina; Ruiz-Pinto, Sara; Carracedo, Angel; Rodríguez-Antona, Cristina

    2016-03-01

    In this article, we present the progress driven by the recent technological advances and new revolutionary massive sequencing technologies in the field of human genetics. We discuss this knowledge in relation with drug response prediction, from the germline genetic variation compiled in the 1000 Genomes Project or in the Genotype-Tissue Expression project, to the phenome-genome archives, the international cancer projects, such as The Cancer Genome Atlas or the International Cancer Genome Consortium, and the epigenetic variation and its influence in gene expression, including the regulation of drug metabolism. This review is based on the lectures presented by the speakers of the Symposium "Human Genetics: International Projects & New Technologies" from the VII Conference of the Spanish Pharmacogenetics and Pharmacogenomics Society, held on the 20th and 21st of April 2015.

  11. Human Insecurity: Understanding International Migration from A Human Security Perspective

    Directory of Open Access Journals (Sweden)

    Francesca Vietti

    2013-07-01

    Full Text Available This article examines contemporary, mass migration from the perspective of human security. It tracks the development of the human security model of international relations, and compares it to the well-established state security model that has served as the dominant paradigm for international relations since the seventeenth century. The article argues that human security offers a more effective approach to many of the underlying problems and threats associated with mass migration, than does the traditional state-security model.  It challenges national and international authorities to address threats to human security, in order to minimize forced migration and to create the conditions for migration by choice, not necessity.

  12. Education, Social Cohesion, and the Future Role of International Organizations.

    Science.gov (United States)

    Heyneman, Stephen P.

    2003-01-01

    Summarizes social cohesion issues within education, concerns over how education performs this function, and implications for international organizations. The paper reviews the purposes of public education, discusses some modern challenges to these traditional functions and why it may be important for international organizations to assume a new…

  13. Curricula and Organization of Primary Care Residencies in Internal Medicine.

    Science.gov (United States)

    Eisenberg, John M.

    1980-01-01

    The organization and curricula of internal medicine residencies programs that emphasize primary care are described and compared with traditional residencies in internal medicine. It is noted that primary care residents spend more time in ambulatory care and are allowed more electives in specialties outside of internal medicine. Out-of-hospital…

  14. “GAY RIGHTS ARE HUMAN RIGHTS”: : THE FRAMING OF NEW INTERPRETATIONS OF INTERNATIONAL HUMAN RIGHTS NORMS

    NARCIS (Netherlands)

    Holzhacker, Ron

    2014-01-01

    “Gay Rights are Human Rights” may have begun as a slogan chanted in the street, but academics and human rights organizations began to use the international human rights frame systematically in the 1990s to argue for universal human rights to fully apply to LGBT persons. This framing gradually began

  15. “GAY RIGHTS ARE HUMAN RIGHTS”: : THE FRAMING OF NEW INTERPRETATIONS OF INTERNATIONAL HUMAN RIGHTS NORMS

    NARCIS (Netherlands)

    Holzhacker, Ron

    2014-01-01

    “Gay Rights are Human Rights” may have begun as a slogan chanted in the street, but academics and human rights organizations began to use the international human rights frame systematically in the 1990s to argue for universal human rights to fully apply to LGBT persons. This framing gradually began

  16. Protection and Effective Functioning of International Organizations. Final Report International Institutional Law; Secure Haven project

    NARCIS (Netherlands)

    Dikker Hupkes, S.D.

    2009-01-01

    This report deals with the legal relationship between International Organizations and their host states. It focuses on the ways in which the effective functioning of those International Organizations is ensured in the relevant seat agreements and multilateral treaties. The report deals specifically

  17. Students' Understandings of Human Organs and Organ Systems.

    Science.gov (United States)

    Reiss, Michael J.; Tunnicliffe, Sue Dale

    2001-01-01

    Discusses students' understandings of their own internal structure. Analysis shows the extent to which student understanding increases with age and the degree to which students know more about some organs and organ systems than others. Gender differences in the drawings were generally not large and there were some intriguing differences in the…

  18. 26 CFR 1.1441-8 - Exemption from withholding for payments to foreign governments, international organizations...

    Science.gov (United States)

    2010-04-01

    ... foreign governments, international organizations, foreign central banks of issue, and the Bank for... payments to foreign governments, international organizations, foreign central banks of issue, and the Bank...). (d) Exemption for payments to international organizations. A payment to an international...

  19. Public Discourse on Human Trafficking in International Issue Arenas

    Directory of Open Access Journals (Sweden)

    Niina Meriläinen

    2015-01-01

    Full Text Available The purpose of this study is to better understand how the complex problem of human trafficking is addressed in international debates. How the discussion about human trafficking develops and how it is debated ultimately influences how the decision-making process unfolds. In order to understand the formation of public policy and laws, therefore, it is important to study the debate that occurs prior to decision making. This analysis focuses on the narratives used by major, well-established human rights and political actors that argue for necessary actions to be undertaken—such as the formation of new policies and laws in the European Union—as an attempt to protect citizens of the EU and other regions in the world from becoming victims of trafficking networks. Our research examines how the topic of human trafficking is framed and how this framework is intertwined in the debate with other social problems. We focus on how human trafficking is discussed by two well-established human rights Non-Governmental Organizations (NGOs, Amnesty International (Amnesty and Human Rights Watch (HRW, in addition to the European Parliament (EP. The research questions for this study include: (1 In what context is human trafficking discussed by the three actors? (2 How do these actors frame the definition of human trafficking in their presentations? To answer these questions, we have conducted a systematic content analysis of documents that include official statements and research reports of the NGOs, as well as resolutions and recommendations of the EP. Altogether, 240 documents were analyzed in detail. These findings indicate that the two human rights organizations, Amnesty and Human Rights Watch, along with the European Parliament, all address human trafficking as an important social problem, albeit to varying degrees. Each actor has a different method of correlating human trafficking with many other social problems, thereby emphasizing different causes and

  20. ASPECTS REGARDING INTERNATIONAL RESPONSIBILITY BY ANALYSING THE AGENCY RELATIONSHIP BETWEEN THE INTERNATIONAL ORGANIZATION AND THE STATE

    Directory of Open Access Journals (Sweden)

    Ovidiu-Emilian IVĂNESCU

    2016-05-01

    Full Text Available The study analyses the consequences for the responsibility of the organization and the relevant state of an agency relationship between an international organization acting as a principal and a state acting as its agent. It is prouved that an international organization may be responsible for damage caused by the conduct of the state. We can also sustain that the state itself may bear responsability for having established or for not having terminated the agency relationship if it commits wrongful conduct on behalf of the international organization.

  1. Reproductive cloning and human health: an ethical, international, and nursing perspective.

    Science.gov (United States)

    Sanchez-Sweatman, L R

    2000-03-01

    Human reproductive cloning came to the public's attention when Dolly, a sheep, was cloned in Scotland in 1997. This news quickly spread around the world causing both excitement at the possibilities that cloning techniques could offer, as well as apprehension about the ethical, social and legal implications should human reproductive cloning become possible. Many international organizations, such as the World Health Organization, the International Council of Nurses, and governments were concerned about the impact of human reproductive cloning on human health, dignity and human rights. To this end, many institutions have drafted resolutions, protocols and position statements outlining their concerns. This paper will outline some of the major ethical issues surrounding human reproductive cloning, the position of various international organizations and governments, and specifically the position of the International Council of Nurses.

  2. The privileges and immunities of international organizations in domestic courts

    CERN Document Server

    2013-01-01

    International organizations are increasingly operating across borders and engaging in legal transactions in virtually all jurisdictions. This makes, familiarity with the applicable law and practice imperative for both international organizations and those who engage in legal relations with them. Furthermore, the issue of whether, how, and to what extent domestic courts take into account decisions of foreign and international courts and tribunals in their own decision-making has become increasingly important in recent years. This book provides a comprehensive empirical study of this transnational judicial dialogue, focusing on the law and practice of domestic jurisdictions concerning the legal personality, privileges, and immunities of international organizations. It presents a selection of detailed country-by-country studies, examining the manner of judicial dialogue across domestic jurisdictions, and between national and international courts. The approach taken in this book intersects with three highly topi...

  3. Internal flows of organism. Seitainai no nagare

    Energy Technology Data Exchange (ETDEWEB)

    Ryumae, S. (Tokyo Inst. of Technology, Tokyo (Japan). Faculty of Engineering)

    1993-08-15

    Introduction is given about features of flows in living things and about some flow phenomena that have been subjects of current researches, and methodological problems involved in the researches are explained. There are some different features of the flow in living things from those in artificial flow. The structural elements of the former flow (channels, fluid, flow change) vary in accordance with environment, activity state and health conditions. Explanation is given about features of the blood flow in the human body, with figures and a table of blood state on being pulsed out from the left cardiac, mean flow phases in the human systemic circulation, change of wave shapes of blood pressure, viscosity of blood, characteristics of vessel elasticity and collapsible flow, representative values of blood dynamics in each blood vessel. With regard to the respiratory system, features of air flow in human lung respiration are explained with figures of a branching model of air ways, a model of respiratory mechanism, relation between inner pressure and inner volume in the lung, total resistance of the air way in each branched generation, flow rate distribution formed by vibration flow and Pendelluft effect. Three problems in handling the flow in living things are pointed out, namely measurement of the state in living things as it is, by non-invasive means, analysis of phenomenon occuring in non-steady fluctuation and individual difference in the flow. 5 refs., 12 figs., 1 tab.

  4. North Atlantic Treaty Organization, the United States, and International Legitimacy

    Science.gov (United States)

    2014-05-22

    8. 42Following the signing of the Treaty of Versailles in 1919, the Albanian State was created but with only one-half of the Albanian population...NORTH ATLANTIC TREATY ORGANIZATION, THE UNITED STATES, AND INTERNATIONAL LEGITIMACY A Monograph by MAJ Mark Van Gelder...North Atlantic Treaty Organization, The United States, and International Legitimacy 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

  5. International energy: Research organizations, 1988--1992. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Hendricks, P.; Jordan, S. [eds.] [USDOE Office of Scientific and Technical Information, Oak Ridge, TN (United States)

    1993-06-01

    This publication contains the standardized names of energy research organizations used in energy information databases. Involved in this cooperative task are (1) the technical staff of the US DOE Office of Scientific and Technical Information (OSTI) in cooperation with the member countries of the Energy Technology Data Exchange (ETDE) and (2) the International Nuclear Information System (INIS). ETDE member countries are also members of the International Nuclear Information System (INIS). Nuclear organization names recorded for INIS by these ETDE member countries are also included in the ETDE Energy Database. Therefore, these organization names are cooperatively standardized for use in both information systems. This publication identifies current organizations doing research in all energy fields, standardizes the format for recording these organization names in bibliographic citations, assigns a numeric code to facilitate data entry, and identifies report number prefixes assigned by these organizations. These research organization names may be used in searching the databases ``Energy Science & Technology`` on DIALOG and ``Energy`` on STN International. These organization names are also used in USDOE databases on the Integrated Technical Information System. Research organizations active in the past five years, as indicated by database records, were identified to form this publication. This directory includes approximately 31,000 organizations that reported energy-related literature from 1988 to 1992 and updates the DOE Energy Data Base: Corporate Author Entries.

  6. The Education Policies of International Organizations: Specific Differences and Convergences

    Science.gov (United States)

    Akkari, Abdeljalil; Lauwerier, Thibaut

    2015-01-01

    This article analyzes the role that international organizations play in orienting education reforms and changes, based on an examination of key texts these organizations produced in the 1990s. The analysis shows that some specific trends persist: UNESCO and UNICEF centre their philosophy on a humanistic and child-centered vision of education,…

  7. 17 CFR 200.72 - Supervision of internal organization.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Supervision of internal organization. 200.72 Section 200.72 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.72 Supervision...

  8. The Education Policies of International Organizations: Specific Differences and Convergences

    Science.gov (United States)

    Akkari, Abdeljalil; Lauwerier, Thibaut

    2015-01-01

    This article analyzes the role that international organizations play in orienting education reforms and changes, based on an examination of key texts these organizations produced in the 1990s. The analysis shows that some specific trends persist: UNESCO and UNICEF centre their philosophy on a humanistic and child-centered vision of education,…

  9. International Space Station Research Benefits for Humanity

    Science.gov (United States)

    Thumm, Tracy; Robinson, Julie A.; Johnson-Green, Perry; Buckley, Nicole; Karabadzhak, George; Nakamura, Tai; Kamigaichi, Shigeki; Sorokin, Igor V.; Zell, Martin; Fuglesang, Christer; Sabbagh, Jean; Pignataro, Salvatore

    2012-01-01

    The ISS partnership has seen a substantial increase in research accomplished, crew efforts devoted to research, and results of ongoing research and technology development. The ISS laboratory is providing a unique environment for research and international collaboration that benefits humankind. Benefits come from the engineering development, the international partnership, and from the research results. Benefits can be of three different types: scientific discovery, applications to life on Earth, and applications to future exploration. Working across all ISS partners, we identified key themes where the activities on the ISS improve the lives of people on Earth -- not only within the partner nations, but also in other nations of the world. Three major themes of benefits to life on earth emerged from our review: benefits to human health, education, and Earth observation and disaster response. Other themes are growing as use of the ISS continues. Benefits to human health range from advancements in surgical technology, improved telemedicine, and new treatments for disease. Earth observations from the ISS provide a wide range of observations that include: marine vessel tracking, disaster monitoring and climate change. The ISS participates in a number of educational activities aimed to inspire students of all ages to learn about science, technology, engineering and mathematics. To date over 63 countries have directly participated in some aspect of ISS research or education. In summarizing these benefits and accomplishments, ISS partners are also identifying ways to further extend the benefits to people in developing countries for the benefits of humankind.

  10. International Space Station Benefits for Humanity

    Science.gov (United States)

    Thumm, Tracy L.; Robinson, Julie A.; Buckley, Nicole; Johnson-Green, Perry; Kamigaichi, Shigeki; Karabadzhak, George; Nakamura, Tai; Sabbagh, Jean; Sorokin, Igor; Zell, Martin

    2012-01-01

    The ISS partnership has seen a substantial increase in research accomplished, crew efforts devoted to research, and results of ongoing research and technology development. The ISS laboratory is providing a unique environment for research and international collaboration that benefits humankind. Benefits come from the engineering development, the international partnership, and from the research results. Benefits can be of three different types: scientific discovery, applications to life on Earth, and applications to future exploration. Working across all ISS partners, we identified key themes where the activities on the ISS improve the lives of people on Earth--not only within the partner nations, but also in other nations of the world. Three major themes of benefits to life on earth emerged from our review: benefits to human health, education, and Earth observation and disaster response. Other themes are growing as use of the ISS continues. Benefits to human health range from advancements in surgical technology, improved telemedicine, and new treatments for disease. Earth observations from the ISS provide a wide range of observations that include: marine vessel tracking, disaster monitoring and climate change. The ISS participates in a number of educational activities aimed to inspire students of all ages to learn about science, technology, engineering and mathematics. To date over 63 countries have directly participated in some aspect of ISS research or education. In summarizing these benefits and accomplishments, ISS partners are also identifying ways to further extend the benefits to people in developing countries for the benefits of humankind.

  11. Does organ selling violate human dignity?

    Science.gov (United States)

    Alpinar-Şencan, Zümrüt; Baumann, Holger; Biller-Andorno, Nikola

    2017-07-11

    Shortages in the number of donated organs after death and the growing number of end-stage organ failure patients on waiting lists call for looking at alternatives to increase the number of organs that could be used for transplantation purposes. One option that has led to a legal and ethical debate is to have regulated markets in human organs. Opponents of a market in human organs offer different arguments that are mostly founded on contingent factors that can be adjusted. However, some authors have asked the question whether we still have a reason to believe that there is something wrong with offering human organs for sale for transplantation purposes, even if the circumstances under which the practice takes place are improved. One prominent argument regarding this appeals to the notion of human dignity. It is argued that organ selling violates human dignity. This paper presents a systematic discussion of dignity-based arguments in the organ selling debate, and then develops a social account of dignity. It is argued that allowing the practice of organ selling inherently runs the risk of promoting the notion that some persons have less worth than others and that persons have a price, which is incompatible with dignity. The approach is defended against possible objections and it is shown that it can capture the notion that autonomy is linked to human dignity in important ways, while dignity at the same time can constrain the autonomous choices of persons with regards to certain practices.

  12. Does international family nursing need a professional organization?

    Science.gov (United States)

    Curry, Donna Miles

    2007-11-01

    An International Family Nursing Conference has been held on a periodic basis since the 1980s. It started with several nursing professionals with a common interest: wanting to meet to share research and practice ideas. The organization of these conferences has been completely voluntary and sponsored by some very benevolent individuals and an institution of higher education. The fact that any of these conferences came off is attributed to considerable personal financial support and an untold number of volunteer hours. A group met in 2005 at the 7th International Family Nursing Conference in Victoria, British Columbia, Canada, to discuss whether there was any interest in forming a professional organization for family nursing. This article explores the cost/ benefits of such an endeavor. Input from other small newly created professional nursing organizations is shared. Conclusions provide summative questions related to development of a formal international professional nursing organization that family nurses must address.

  13. International infectious disease law: revision of the World Health Organization's International Health Regulations.

    Science.gov (United States)

    Gostin, Lawrence O

    2004-06-02

    The International Health Regulations (IHR), the only global regulations for infectious disease control, have not been significantly changed since they were first issued in 1951. The World Health Organization (WHO) is currently engaged in a process to modernize the IHR. This article reviews WHO's draft revised IHR and recommends new reforms to improve global health, which include (1) a robust mission, emphasizing the WHO's core public health purposes, functions, and essential services; (2) broad scope, flexibly covering diverse health threats; (3) global surveillance, developing informational networks of official and unofficial data sources; (4) national public health systems, setting performance criteria, measuring outcomes, and holding states accountable; (5) human rights protection, setting science-based standards and fair procedures; and (6) good governance, adopting the principles of fairness, objectivity, and transparency. The WHO should ensure state compliance with health norms and generous economic and technical assistance to poorer countries. An important issue for the international community is how sovereign countries can join together to make global health work for everyone, the poor and the wealthy alike.

  14. Learning organizations, internal marketing, and organizational commitment in hospitals.

    Science.gov (United States)

    Tsai, Yafang

    2014-04-04

    Knowledge capital is becoming more important to healthcare establishments, especially for hospitals that are facing changing societal and industrial patterns. Hospital staff must engage in a process of continual learning to improve their healthcare skills and provide a superior service to their patients. Internal marketing helps hospital administrators to improve the quality of service provided by nursing staff to their patients and allows hospitals to build a learning culture and enhance the organizational commitment of its nursing staff. Our empirical study provides nursing managers with a tool to allow them to initiate a change in the attitudes of nurses towards work, by constructing a new 'learning organization' and using effective internal marketing. A cross-sectional design was employed. Two hundred questionnaires were distributed to nurses working in either a medical centre or a regional hospital in Taichung City, Taiwan, and 114 valid questionnaires were returned (response rate: 57%). The entire process of distribution and returns was completed between 1 October and 31 October 2009. Hypothesis testing was conducted using structural equation modelling. A significant positive correlation was found between the existence of a 'learning organization', internal marketing, and organizational commitment. Internal marketing was a mediator between creating a learning organization and organizational commitment. Nursing managers may be able to apply the creation of a learning organization to strategies that can strengthen employee organizational commitment. Further, when promoting the creation of a learning organization, managers can coordinate their internal marketing practices to enhance the organizational commitment of nurses.

  15. A human rights approach to human trafficking for organ removal.

    Science.gov (United States)

    Budiani-Saberi, Debra; Columb, Seán

    2013-11-01

    Human trafficking for organ removal (HTOR) should not be reduced to a problem of supply and demand of organs for transplantation, a problem of organized crime and criminal justice, or a problem of voiceless, abandoned victims. Rather, HTOR is at once an egregious human rights abuse and a form of human trafficking. As such, it demands a human-rights based approach in analysis and response to this problem, placing the victim at the center of initiatives to combat this phenomenon. Such an approach requires us to consider how various measures impact or disregard victims/potential victims of HTOR and gives us tools to better advocate their interests, rights and freedoms.

  16. Interns at an International, Humanitarian Organization: Career Pathways and Meaning Making

    Science.gov (United States)

    Mather, Peter C.

    2008-01-01

    This qualitative study examined the career shaping experiences and related meaning making processes of 12 interns at The Carter Center, an international, humanitarian organization. Experiences shaping participants' careers were grouped into the following themes--academics and intellectual curiosity; travel abroad; religion; relationships--family,…

  17. What International Aid Organizations Can Learn from International Adult Learning: Experiences from Cambodia

    Science.gov (United States)

    Berkvens, Jan

    2012-01-01

    Purpose: Many countries receive international support to strengthen professional capacity. The effect of these professional development activities (PDAs), however, is often negligible. This article provides useful insights on how international aid organizations could improve their PDAs, by describing an intervention developed and applied in…

  18. 19 CFR 145.39 - Articles for diplomatic officers, representatives of international organizations, and foreign...

    Science.gov (United States)

    2010-04-01

    ... of international organizations, and foreign military personnel. 145.39 Section 145.39 Customs Duties..., representatives of international organizations, and foreign military personnel. Free entry of articles in mail articles addressed to diplomatic officers, representatives of certain international organizations,...

  19. 77 FR 53250 - International Civil Aviation Organization's (ICAO) Dangerous Goods Panel; Notice of Public Meeting

    Science.gov (United States)

    2012-08-31

    ... Federal Aviation Administration International Civil Aviation Organization's (ICAO) Dangerous Goods Panel... meeting. SUMMARY: In preparation for the International Civil Aviation Organization's (ICAO) Dangerous... International Civil Aviation Organization's Dangerous Goods Panel's (ICAO DGP's) Working Group of the Whole...

  20. 78 FR 16756 - International Civil Aviation Organization's (ICAO) Dangerous Goods Panel; Notice of Public Meeting

    Science.gov (United States)

    2013-03-18

    ... Federal Aviation Administration International Civil Aviation Organization's (ICAO) Dangerous Goods Panel... meeting. SUMMARY: In preparation for the International Civil Aviation Organization's (ICAO) Dangerous... prepares for the International Civil Aviation Organization's Dangerous Goods Panel's (ICAO DGP's)...

  1. INMARSAT - The International Maritime Satellite Organization: Origins and structure

    Science.gov (United States)

    Doyle, S. E.

    1977-01-01

    The third session of the International Conference on the Establishment of an International Maritime Satellite System established the International Maritime Satellite Organization (INMARSAT) in 1976. Its main functions are to improve maritime communications via satellite, thereby facilitating more efficient emergency communications, ship management, and maritime public correspondence services. INMARSAT's aims are similar to those of the Intergovernmental Maritime Consultative Organization (IMCO), the main United Nations organization dealing with maritime affairs. The specific functions of INMARSAT have been established by an Intersessional Working Group (IWG) which met three times between general conference meetings. Initial investment shares for the creation of INMARSAT were shared by the United States (17%), the United Kingdom (12%), the U.S.S.R. (11%), Norway (9.50%), Japan (8.45%), Italy (4.37%), and France (3.50%).

  2. Outplacement Services for Displaced Employees: Attitudes of Human Resource Managers Based on Differences in Internal and External Delivery

    Science.gov (United States)

    Kilcrease, Kelly M.

    2013-01-01

    The results from a survey of 238 human resources executives from organizations that offer outplacement counseling (OPC) internally and 168 that offer it externally suggest that internal OPC delivery is inferior to external OPC delivery. The author found that most internal OPC organizations did not offer the 13 traditional OPC services, even when…

  3. Outplacement Services for Displaced Employees: Attitudes of Human Resource Managers Based on Differences in Internal and External Delivery

    Science.gov (United States)

    Kilcrease, Kelly M.

    2013-01-01

    The results from a survey of 238 human resources executives from organizations that offer outplacement counseling (OPC) internally and 168 that offer it externally suggest that internal OPC delivery is inferior to external OPC delivery. The author found that most internal OPC organizations did not offer the 13 traditional OPC services, even when…

  4. Microfabrication of human organs-on-chips.

    Science.gov (United States)

    Huh, Dongeun; Kim, Hyun Jung; Fraser, Jacob P; Shea, Daniel E; Khan, Mohammed; Bahinski, Anthony; Hamilton, Geraldine A; Ingber, Donald E

    2013-11-01

    'Organs-on-chips' are microengineered biomimetic systems containing microfluidic channels lined by living human cells, which replicate key functional units of living organs to reconstitute integrated human organ-level pathophysiology in vitro. These microdevices can be used to test efficacy and toxicity of drugs and chemicals, and to create in vitro models of human disease. Thus, they potentially represent low-cost alternatives to conventional animal models for pharmaceutical, chemical and environmental applications. Here we describe a protocol for the fabrication, microengineering and operation of these microfluidic organ-on-chip systems. First, microengineering is used to fabricate a multilayered microfluidic device that contains two parallel elastomeric microchannels separated by a thin porous flexible membrane, along with two full-height, hollow vacuum chambers on either side; this requires ∼3.5 d to complete. To create a 'breathing' lung-on-a-chip that mimics the mechanically active alveolar-capillary interface of the living human lung, human alveolar epithelial cells and microvascular endothelial cells are cultured in the microdevice with physiological flow and cyclic suction applied to the side chambers to reproduce rhythmic breathing movements. We describe how this protocol can be easily adapted to develop other human organ chips, such as a gut-on-a-chip lined by human intestinal epithelial cells that experiences peristalsis-like motions and trickling fluid flow. Also, we discuss experimental techniques that can be used to analyze the cells in these organ-on-chip devices.

  5. Solid organ transplantation: the Italian experience in the international context.

    Science.gov (United States)

    Nanni Costa, A; De Cillia, C; Di Ciaccio, P; Rizzato, L; Venettoni, S

    2011-01-01

    The Italian experience in the organization of transplantation procedures could represent a relevant example of an internal development at a national level, combined with a strengthening of international collaborations. These results can be attributed first to the creation of the Italian National Transplant Centre (Centro Nazionale Trapianti [CNT]), and then to an ongoing European process that is leading to a greater awareness of the importance of closer collaboration between the organizations already existing and operating in the field of transplantation. This article summarizes the role and the most significant achievements of the CNT. Copyright © 2011. Published by Elsevier Inc.

  6. Principles of the institutional law of international organizations

    CERN Document Server

    Amerasinghe-Chittharanjan, Felix

    1996-01-01

    Dr Amerasinghe starts with a brief history of international organizations. In fourteen substantive chapters, he then deals with subjects such as interpretation, membership and representation, the doctrine of "ultra vires", responsibility, liability of members to third parties, internal law and employment relations, privileges and immunities, dispute settlement, and, finally, dissolution and succession. There is a full and detailed examination of the problems connected with each of these subjects. The primary object of the book is to discuss principles, but Dr Amerasinghe also studies the law and practice of different organizations, using a rigourous analysis of the material alongside his functional examination of the law.

  7. Nanotechnological Strategies for Biofabrication of Human Organs

    Directory of Open Access Journals (Sweden)

    Rodrigo A. Rezende

    2012-01-01

    Full Text Available Nanotechnology is a rapidly emerging technology dealing with so-called nanomaterials which at least in one dimension have size smaller than 100 nm. One of the most potentially promising applications of nanotechnology is in the area of tissue engineering, including biofabrication of 3D human tissues and organs. This paper focused on demonstrating how nanomaterials with nanolevel size can contribute to development of 3D human tissues and organs which have macrolevel organization. Specific nanomaterials such as nanofibers and nanoparticles are discussed in the context of their application for biofabricating 3D human tissues and organs. Several examples of novel tissue and organ biofabrication technologies based on using novel nanomaterials are presented and their recent limitations are analyzed. A robotic device for fabrication of compliant composite electrospun vascular graft is described. The concept of self-assembling magnetic tissue spheroids as an intermediate structure between nano- and macrolevel organization and building blocks for biofabrication of complex 3D human tissues and organs is introduced. The design of in vivo robotic bioprinter based on this concept and magnetic levitation of tissue spheroids labeled with magnetic nanoparticles is presented. The challenges and future prospects of applying nanomaterials and nanotechnological strategies in organ biofabrication are outlined.

  8. Assessing Summit Engagement with Other International Organizations in Global Governance

    Directory of Open Access Journals (Sweden)

    Marina Larionova

    2016-03-01

    Full Text Available Recent decades have witnessed dramatic changes all over the world. One major trend is the proliferation and diversification of actors, forums and their arrangements to address global governance challenges, which has led to fragmentation in global governance. However, such contested multilateralism has a positive dimension, as the emergence of informal multilateral institutions claiming a major role in defining the global governance agenda creates alternatives for providing common goods. New arrangements acquire their own actorness and place in the system of global governance. In certain policy areas, there is a clear trend for the new summit institutions’ leadership. The most visible recent cases include the Group of 20 (G20, the BRICS group of Brazil, Russia, India, China and South Africa, and the Asia-Pacific Economic Cooperation (APEC forum, with APEC gaining importance regionally and globally. These new informal groupings work on their own agenda. They also engage with established international organizations to steer global governance processes. Taken together, the transformative trends in international relations, the emergence of new actors, tensions between exclusive and inclusive clubs, and demands for the legitimacy and effectiveness of the international institutions define the relevance of the study, systematization and comparative analysis of the effectiveness of this model of cooperation among international institutions. This article builds an analytical framework by undertaking three tasks. It first reviews the key concepts. Second, it argues for a rational choice institutionalist approach. Third, it puts forward a hypothesis for research: to compensate for their inefficiencies, summit institutions engage with other international organizations in a mode they regard most efficient for attainment of their goals. The modes of those institutions’ engagement with other international organizations as reflected in the leaders

  9. How China's Procuratorial Organs Protect Human Rights

    Institute of Scientific and Technical Information of China (English)

    JING DALI

    2011-01-01

    @@ Question: The Twelfth Five-Year Program, which was approved by the 2011 session of the National People's Congress, calls for better protection of human rights and more work to promote China's human rights cause.Would you tell us about the role played by procuratorial organs in this endeavor?

  10. International criminal tribunals and human rights law: Adherence and contextualization

    NARCIS (Netherlands)

    Zeegers, K.J.

    2015-01-01

    Given their mandate to prosecute persons responsible for the most atrocious of human rights violations, International Criminal Tribunals (ICTs) are generally hailed as welcome enforcers of international human rights law: a new instrument in the toolkit of human rights protectors. However, ICTs inves

  11. Human Rights, Human Needs, Human Development, Human Security - Relationships between four international human discourses.

    NARCIS (Netherlands)

    D.R. Gasper (Des)

    2007-01-01

    markdownabstractAbstract: Human rights, human development and human security form increasingly important, partly interconnected, partly competitive and misunderstood ethical and policy discourses. Each tries to humanize a pre-existing and unavoidable major discourse of everyday life, policy and

  12. Towards Participation and Equality: The UN's International Labour Organization.

    Science.gov (United States)

    Konig, A.

    1990-01-01

    The role of the International Labour Organization (ILO) in vocational rehabilitation and employment for people with disabilities is examined. The ILO's recent emphasis on community-based training and employment programs, social reintegration of disabled citizens through self-employment and union-generating activities, and special programs for…

  13. World Regionalization of Higher Education: Policy Proposals for International Organizations

    Science.gov (United States)

    de Prado Yepes, Cesar

    2006-01-01

    International organizations dealing with higher education should pay more attention to the rise of autonomous world regional processes and explore synergies. This article gives an overview of new macro-regional processes around the world. The European case is the most salient, but developments in America and East Asia are also noticeable. In the…

  14. Human skin: an independent peripheral endocrine organ.

    Science.gov (United States)

    Zouboulis, C C

    2000-01-01

    The historical picture of the endocrine system as a set of discrete hormone-producing organs has been substituted by organs regarded as organized communities in which the cells emit, receive and coordinate molecular signals from established endocrine organs, other distant sources, their neighbors, and themselves. In this wide sense, the human skin and its tissues are targets as well as producers of hormones. Although the role of hormones in the development of human skin and its capacity to produce and release hormones are well established, little attention has been drawn to the ability of human skin to fulfil the requirements of a classic endocrine organ. Indeed, human skin cells produce insulin-like growth factors and -binding proteins, propiomelanocortin derivatives, catecholamines, steroid hormones and vitamin D from cholesterol, retinoids from diet carotenoids, and eicosanoids from fatty acids. Hormones exert their biological effects on the skin through interaction with high-affinity receptors, such as receptors for peptide hormones, neurotransmitters, steroid hormones and thyroid hormones. In addition, the human skin is able to metabolize hormones and to activate and inactivate them. These steps are overtaken in most cases by different skin cell populations in a coordinated way indicating the endocrine autonomy of the skin. Characteristic examples are the metabolic pathways of the corticotropin-releasing hormone/propiomelanocortin axis, steroidogenesis, vitamin D, and retinoids. Hormones exhibit a wide range of biological activities on the skin, with major effects caused by growth hormone/insulin-like growth factor-1, neuropeptides, sex steroids, glucocorticoids, retinoids, vitamin D, peroxisome proliferator-activated receptor ligands, and eicosanoids. At last, human skin produces hormones which are released in the circulation and are important for functions of the entire organism, such as sex hormones, especially in aged individuals, and insulin-like growth

  15. How to Brand an International Organization. NATO Case Study

    Directory of Open Access Journals (Sweden)

    Gigi Mihaita

    2011-05-01

    Full Text Available Branding products and companies has always been associated with private enterprises and less, if ever, with international intergovernmental organizations. International organizations now have a long history behind them, a history often marked by contradictory events. In the last decade the international organizations developed their own public relations department in an attempt to communicate promptly and transmit the general audience their version of reality. Having this in mind we will try to briefly present in the current work the main reasons why we believe that the international organizations, NATO in particular, have started to see themselves as brand and to create a so called “commercial identity” by becoming a brand. By applying the conceptual and analytical framework used in analyzing the marketing strategies of the private companies we will try to see whether NATO is about to become a brand. Our starting point will be a 2008 statement of Jean-François Bureau, deputy general secretary responsible with NATO’s public diplomacy: “We have the green light to think about a branding policy for NATO”. Nowadays global society, perceptions tend to become more important than reality itself, and thus positive perceptions tend to become crucial. NATO has suffered an image decline in the last decade, therefore some new communication measures tend to impose themselves. The distinction between soft power and propaganda must be carefully analyzed when we speak about branding NATO. Thus we hope to bring some necessary clarifications in the area of NATO branding. Is there a brand? Is a brand going to be constructed? How does it differ from a commercial society? Does NATO need its own TV channel? Raising questions and offering a new perspective is, in the end, our primary goal, as a debate on this subject is a must that offers a new perspective in the area of theory of international organizations.

  16. Speckle-correlation monitoring of the microhemodynamics of internal organs

    Science.gov (United States)

    Zimnyakov, D. A.; Khmara, M. B.; Vilensky, M. A.; Kozlov, V. V.; Sadovoĭ, A. V.; Gorfinkel, I. V.; Zdrajevsky, R. A.; Isaeva, A. A.

    2009-12-01

    The results of preliminary experimental studies of the possibility of monitoring blood microcirculation in surface layers of internal organs of laboratory animals in the course of laparotomy using full-field speckle correlometry are presented. The transmission of laser radiation to the probed part of the organ and the delivery of scattered speckle-modulated radiation to the detector (a CMOS camera) are performed using a fiberoptic endoscopic system. In the course of experiments, the microhemodynamics of the intestine, liver, spleen, kidneys, and pancreas in rat in a normal state and under induced ischemia and peritonitis, as well as under the action of drugs with clearly pronounced vasodilative effects (lidocaine, papaverine), is studied. The problems and prospects of speckle-correlation monitoring of the microhemodynamics of internal organs under laboratory and clinical conditions are discussed.

  17. Cooperation between International Organizations in Complex Emergencies in Eastern Africa

    DEFF Research Database (Denmark)

    Pradhan-Blach, Flemming; Schaub Jr, Gary John; LeRiche, Matthew

    This report addresses the challenges of cooperation between international organizations in complex emergencies in fragile states of East Africa. An expert seminar was conducted on the basis of a paper on the subject to discuss problems, challenges, and possible solutions. Denmark and the rest...... of the international community often face the problem of poor coordination, lack of cooperation, and de-confliction of assistance in such situations. Countries and organizations are aware of these problems and have undertaken efforts to resolve them, but it remains insufficient. Attempts to better coordinate have been...... made at various levels—between governments, between organizations, and between local actors. Some improvements in effectiveness are being observed. Since 2005, Danish development policy has tried to take these efforts into account, as do policies that are still under development. The necessity...

  18. Cooperation between International Organizations in Complex Emergencies in Eastern Africa

    DEFF Research Database (Denmark)

    Pradhan-Blach, Flemming; Schaub Jr, Gary John; LeRiche, Matthew

    This report addresses the challenges of cooperation between international organizations in complex emergencies in fragile states of East Africa. An expert seminar was conducted on the basis of a paper on the subject to discuss problems, challenges, and possible solutions. Denmark and the rest...... of the international community often face the problem of poor coordination, lack of cooperation, and de-confliction of assistance in such situations. Countries and organizations are aware of these problems and have undertaken efforts to resolve them, but it remains insufficient. Attempts to better coordinate have been...... made at various levels—between governments, between organizations, and between local actors. Some improvements in effectiveness are being observed. Since 2005, Danish development policy has tried to take these efforts into account, as do policies that are still under development. The necessity...

  19. Presence in International Organisms: A Policy for a Collective Challenge

    Directory of Open Access Journals (Sweden)

    Manuel Montobbio

    2006-01-01

    Full Text Available What does the presence of Spaniards in international organisations signify and entail? Why, for what, and how should this be promoted? In order to answer such questions, the author analyses the meaning and implications of this presence in a globalised world in which a commitment to effective multilateralism entails a commitment to the international organisms as forums for and actors in global governance, and their presence in our societies and lives. This means both the promoting of Spanish presence in the administrations inwhich the proposals are formed which embody the general interest of the international organisations, like the multilateralisation of Spanish society. For this reason, in the framework of its multilateral policy, Spain is currently developing a policy of promoting the presence of Spaniards in international organisations in the areas of information, training, promotion and incentives, the outlines and results of which are described in this article.

  20. Toward a Human Rights Method for Measuring International Copyright Law’s Compliance with International Human Rights Law

    Directory of Open Access Journals (Sweden)

    Saleh Al-Sharieh

    2016-04-01

    Full Text Available States parties to international copyright instruments are required to give effect to their obligations under international copyright law and fulfil their international human rights obligations with respect to striking a balance between the human rights of the authors of intellectual works and human rights of the users of those same works. The High Commissioner of Human Rights has concluded that such balance ‘is one familiar to intellectual property law’. This conclusion assumes that international copyright law is already compliant with international human rights law. However, international copyright law instruments are not clear about how to reach an appropriate balance between these rights and, as a result, different stakeholders in the international copyright community seek and defend varied versions of balance which are not necessarily consistent. Concurrently, international human rights law bodies and scholars have examined the human rights of authors and users of intellectual works through a copyright law lens, missing a chance to articulate a clear human rights principle of balance. A proper human rights balance between authors’ and users’ human rights recognises the limited nature of both sets of human rights, rejects any hierarchy between them, and interprets them in conformity with the notion of the interdependence and indivisibility of human rights.

  1. The Role and Purposes of Public Schools and Religious Fundamentalism: An International Human Rights Law Perspective

    Science.gov (United States)

    Hodgson, Douglas Charles

    2012-01-01

    The question of what are today the legitimate and proper role and purposes of public schools can only be answered by a close examination and analysis of the human right to education which has been developed by such international organizations as the United Nations and the United Nations Educational, Scientific and Cultural Organization, and by…

  2. 26 CFR 31.3121(b)(15)-1 - Services in employ of international organization.

    Science.gov (United States)

    2010-04-01

    ... organization. (a) Subject to the provisions of section 1 of the International Organizations Immunities Act (22 U.S.C. 288), services performed in the employ of an international organization as defined in section... with the intent thereof— (18) International organization. The term “international organization” means...

  3. 76 FR 174 - International Business Machines (IBM), Global Sales Operations Organization, Sales and...

    Science.gov (United States)

    2011-01-03

    ... Employment and Training Administration International Business Machines (IBM), Global Sales Operations...; International Business Machines (IBM), Global Sales Operations Organization, Sales and Distribution Business..., applicable to workers of International Business Machines (IBM), Global Sales Operations Organization,...

  4. The proposed market for human organs.

    Science.gov (United States)

    Spurr, S J

    1993-01-01

    During the last decade there have been enormous advances in the transplantation of vital human organs--in particular, the kidney, lung, heart, liver, pancreas, and small intestine. Unfortunately, efforts to provide the benefits of these operations to patients have been severely hindered by limitations in the supply of organs--limitations that are a consequence of regulation prohibiting the use of market incentives to increase the supply. Markets for organs could take various forms: sales by living donors; sales of future interests in organs, to be removed on the death of the donor; and sales of organs of a recently deceased person by the family of the deceased. Two additional issues relate to the design of a market: the geographic scope of the market and rules of liability for the sale of diseased or defective organs.

  5. Organizations And Services In The System Of International Aviation Navigation

    Directory of Open Access Journals (Sweden)

    Alexander I. Travnikov

    2015-03-01

    Full Text Available In the present article author reveals the order of creation, structure, aims and objectives of national and international intergovernmental aeronautical organizations, governing procedure for flight operations and providing direct air traffic control over sovereign territory and abroad. In this article, author notes that in the world there are three main organizational and legal forms of air traffic control systems to ensure coordination between civil and military air navigation services (agencies. In the Russian Federation, author notes that air navigation services on behalf of the State are made by the State Corporation for Air Traffic Management that has the legal status of the commercial organization - the Federal State Unitary Enterprise. Author analyzes the work of the Organization for the Civil Air Navigation Services (CANSO, the International Federation of Air Traffic Controllers (IFATCA. During the study author also concludes that in the past decade, there is the steady trend of transferring functions of air navigation from the State to commercial organizations (joint stock companies and limited liability companies, which are financed from the funds received as payment for air traffic services. The responsibility for the improper maintenance of international air navigation, of course, is borne by the State. Author notes that regional and international intergovernmental aeronautical organizations operate in respect of all aircraft (public, civil, experimental, i.e., perform general air navigation, unlike ICAO, which takes standards and recommended practices, rules and procedures for safety and air traffic services only to civil aircraft, that does not ensure the creation of a regulatory framework for the global unification of aeronautical processes.

  6. Self-organized Criticality Model for Ocean Internal Waves

    Institute of Scientific and Technical Information of China (English)

    WANG Gang; LIN Min; QIAO Fang-Li; HOU Yi-Jun

    2009-01-01

    In this paper, we present a simple spring-block model for ocean internal waves based on the self-organized criticality (SOC). The oscillations of the water blocks in the model display power-law behavior with an exponent of-2 in the frequency domain, which is similar to the current and sea water temperature spectra in the actual ocean and the universal Garrett and Munk deep ocean internal wave model [Geophysical Fluid Dynamics 2 (1972) 225; J. Geophys. Res. 80 (1975) 291]. The influence of the ratio of the driving force to the spring coefficient to SOC behaviors in the model is also discussed.

  7. G20: Engaging with International Organizations to Generate Growth

    Directory of Open Access Journals (Sweden)

    Marina Larionova

    2017-08-01

    Full Text Available Born in response to economic and financial crises which existing institutions were unable to address adequately, the G20 transformed from a crisis management group into the premier forum for international economic cooperation. Like its predecessor, the G7 (which was set up in 1975, and BRICS (established in 2009, G20 is an informal club or summit institution. To ensure continuity, legitimacy and efficiency in fulfilling their global governance functions of deliberation, direction-setting, decision-making, delivery and the development of global governance, the G20 members engage other international organizations. It is hypothesized that to maximize benefits from its engagement with international organizations, the G20 resorts to a combination of the “catalyst”, “core group” and “parallel treatment” approaches exercised by summit institutions. These include exerting an influence in promoting changes to international organizations through endorsement or stimulus, compelling them to reform, imparting a new direction by giving a lead that the other organizations would follow, and creating original mechanisms, working in parallel with existing institutions. The article tests this assumption. To trace the dynamics of G20 engagement with multilateral organizations and identify preferred models across the presidencies and policy areas, the analysis is carried out within the rational choice institutionalist paradigm, drawing on the quantitative and qualitative analysis of documents adopted by the G20. Findings from the study indicate that the intensity of the G20 engagement with the IOs is very high and G20 mostly resorts to a combination of the catalyst and core group approaches, though the pattern depends on the policy area, the IOs and the presidency agenda. The intensity of G20 engagement with the IMF, Financial Stability Board, World Bank, and Organization for Economic Co-operation and Development by far exceeds the intensity of its

  8. Human Rights, Human Needs, Human Development, Human Security : Relationships between four international 'human' discourses

    NARCIS (Netherlands)

    D.R. Gasper (Des)

    2007-01-01

    textabstractHuman rights, human development and human security form increasingly important, partly interconnected, partly competitive and misunderstood ethical and policy discourses. Each tries to humanize a pre-existing and unavoidable major discourse of everyday life, policy and politics; each

  9. Organic Fertilisation, Soil Quality and Human Health

    OpenAIRE

    2012-01-01

    Chapters: 1) Convergence or divide in the movement for sustainable and just agriculture. 2) No-till agriculture in the USA. 3) Organic fertilizers in sub-Saharan farming systems. 4) Biofuel Production Byproducts as Soil Amendments. 5) Pseudomonas and microbes for disease-suppressive soils. 6) Conservation Tillage Impact on Soil Aggregation, Organic Matter Turnover and Biodiversity. 7) Sustainable agricultural NP turnover in the 27 European countries. 8) Tomato production for human health, not...

  10. Perfused human organs versus Mary Shelley's Frankenstein

    Directory of Open Access Journals (Sweden)

    Leung Lawrence

    2009-01-01

    Full Text Available Abstract Novel drugs have to go through mandatory pre-clinical testing before they can be approved for use in clinical trials. In essence, it is a form of bench-to-bedside (N2B translational medicine, but the wastage rate of target candidates is immensely high. Effects seen in vitro often do not translate to in vivo human settings. The search is on for better models closer to human physiology to be used in pre-clinical drug screening. The Ex Vivo Metrics© system has been introduced where a human organ is harvested and revitalized in a controlled environment suitable for testing of both drug efficacy and potential toxicity. This commentary expresses the author's views regarding this technology of perfused human organs.

  11. Perfused human organs versus Mary Shelley's Frankenstein.

    Science.gov (United States)

    Leung, Lawrence

    2009-01-23

    Novel drugs have to go through mandatory pre-clinical testing before they can be approved for use in clinical trials. In essence, it is a form of bench-to-bedside (N2B) translational medicine, but the wastage rate of target candidates is immensely high. Effects seen in vitro often do not translate to in vivo human settings. The search is on for better models closer to human physiology to be used in pre-clinical drug screening. The Ex Vivo Metrics system has been introduced where a human organ is harvested and revitalized in a controlled environment suitable for testing of both drug efficacy and potential toxicity. This commentary expresses the author's views regarding this technology of perfused human organs.

  12. Marketing human organs: the autonomy paradox.

    Science.gov (United States)

    Marshall, P A; Thomasma, D C; Daar, A S

    1996-03-01

    The severe shortage of organs for transplantation and the continual reluctance of the public to voluntarily donate has prompted consideration of alternative strategies for organ procurement. This paper explores the development of market approaches for procuring human organs for transplantation and considers the social and moral implications of organ donation as both a "gift of life" and a "commodity exchange." The problematic and paradoxical articulation of individual autonomy in relation to property rights and marketing human body parts is addressed. We argue that beliefs about proprietorship over human body parts and the capacity to provide consent for organ donation are culturally constructed. We contend that the political and economic framework of biomedicine, in western and non-western nations, influences access to transplantation technology and shapes the form and development of specific market approaches. Finally, we suggest that marketing approaches for organ procurement are and will be negotiated within cultural parameters constrained by several factors: beliefs about the physical body and personhood, religious traditions, economic conditions, and the availability of technological resources.

  13. 78 FR 59413 - International Civil Aviation Organization's (ICAO) Dangerous Goods Panel; Notice of Public Meeting

    Science.gov (United States)

    2013-09-26

    ... Federal Aviation Administration International Civil Aviation Organization's (ICAO) Dangerous Goods Panel... meeting. SUMMARY: In preparation for the International Civil Aviation Organization's (ICAO) Dangerous... Organization's Dangerous Goods Panel's (ICAO DGP's) 24th Panel Meeting. The agenda for the Working Group is...

  14. (Dis)organizing through imbrications of human and material agencies

    DEFF Research Database (Denmark)

    Tavella, Elena

    and material agencies. However there is a lack of insight into how human and material agencies are imbricated during the emergence of (dis)order, and how different imbrications lead to (dis)order. This paper addresses this gap by presenting a content analysis of a book reporting the Battle of Stalingrad during...... to organize different activities within one and the same organizational context, which led to (dis)order. Whether order or disorder emerged was dependent on how human and material agencies were imbricated within the conduct of particular activities, and how they related to internal or external influencing...

  15. Foundations of Collective Cultural Rights in International Human Rights Law

    NARCIS (Netherlands)

    Donders, Y.; Jakubowski, A.

    2016-01-01

    Although collective cultural rights are included in international human rights law, their place and their nature and significance are not well-explored or understood. This chapter aims to classify collective cultural rights in international human rights instruments and to explore how these rights

  16. Human rights and the requirement for international medical aid.

    Science.gov (United States)

    Tolchin, Benjamin

    2008-08-01

    Every year approximately 18 million people die prematurely from treatable medical conditions including infectious diseases and nutritional deficiencies. The deaths occur primarily amongst the poorest citizens of poor developing nations. Various groups and individuals have advanced plans for major international medical aid to avert many of these unnecessary deaths. For example, the World Health Organization's Commission on Macroeconomics and Health estimated that eight million premature deaths could be prevented annually by interventions costing roughly US$57 bn per year. This essay advances an argument that human rights require high-income nations to provide such aid. The essay briefly examines John Rawls' obligations of justice and the reasons that their applicability to cases of international medical aid remains controversial. Regardless, the essay argues that purely humanitarian obligations bind the governments and citizens of high-income liberal democracies at a minimum to provide major medical aid to avert premature deaths in poor nations. In refusing to undertake such medical relief efforts, developed nations fail to adequately protect a fundamental human right to life.

  17. From Internal Marketing to Human Resource Marketing. A Conceptual Framework of the Human Resources Marketing

    OpenAIRE

    Neagu Olimpia

    2011-01-01

    The paper focuses on shaping a conceptual framework of the human resources marketing, having as starting points the interactions between internal marketing and human management resources at the organisation’s level. The concept of internal customers, belonging to internal marketing and refering to the employees, can be taken in the human resources marketing as focus of the specific processes.

  18. A Competitive Market in Human Organs

    Directory of Open Access Journals (Sweden)

    Danny Frederick

    2010-11-01

    Full Text Available I offer consequentialist and deontological arguments for a competitive market in human organs, from live as well as dead donors. I consider the objections that a market in organs will frustrate altruism, coerce the desperate, expose under-informed agents to unacceptable risks, exacerbate inequality, degrade those who participate in it, involve a kind of slavery, impose invidious costs, and impair third-party choice sets. I show that each of these objections is without merit and that, in consequence, the opposition to markets in organs is an untenable endorsement of death, suffering and the suppression of freedom.

  19. The International Humanitarian Response to the Refugee Crisis Along the Balkan Route in the View of Strategies of International Organizations

    Directory of Open Access Journals (Sweden)

    Latifi Veton

    2017-06-01

    Full Text Available Being one of the largest movements of displaced people through European borders since World War Two, the Syrian refugee crisis of 2015 and 2016, tested the coordination of the states and international organizations, and as well as the strategies for response of the latter to such enormous fluxes of displaced people along the Balkan corridor. The quick on-time reaction of the specialized humanitarian international organizations made significant achievements by the international organizations in terms of humanitarian assistance for the refugees and support for the governments of the region. Their approach mainly sought to create a partnership with the governments of the Balkan route in handling the serious humanitarian challenges (with a different strategy compared to other experiences, mainly this time through providing assistance and protection to the refugees throughout the corridor of the refugee crisis, it showed how important is such coordination at the end, with an aim to avoid further human catastrophes along refugee routes, and to avoid major security repercussions for the countries of the region.

  20. International Human Rights and the Mistreatment of Women During Childbirth.

    Science.gov (United States)

    Khosla, Rajat; Zampas, Christina; Vogel, Joshua P; Bohren, Meghan A; Roseman, Mindy; Erdman, Joanna N

    2016-12-01

    International human rights bodies have played a critical role in codifying, setting standards, and monitoring human rights violations in the context of sexual and reproductive health and rights. In recent years, these institutions have developed and applied human rights standards in the more particular context of maternal mortality and morbidity, and have increasingly recognized a critical human rights issue in the provision and experience of care during and after pregnancy, including during childbirth. However, the international human rights standards on mistreatment during facility-based childbirth remain, in an early stage of development, focused largely on a discrete subset of experiences, such as forced sterilization and lack of access to emergency obstetric care. As a consequence, the range of mistreatment that women may experience has not been adequately addressed or analyzed under international human rights law. Identifying human rights norms and standards related to the full range of documented mistreatment is thus a first step towards addressing violations of human rights during facility-based childbirth, ensuring respectful and humane treatment, and developing a program of work to improve the overall quality of maternal care. This article reviews international human rights standards related to the mistreatment of women during childbirth in facility settings under regional and international human rights law and lays out an agenda for further research and action.

  1. International Human Rights and the Mistreatment of Women During Childbirth

    Science.gov (United States)

    Zampas, Christina; Vogel, Joshua P.; Bohren, Meghan A.; Roseman, Mindy; Erdman, Joanna N.

    2016-01-01

    Abstract International human rights bodies have played a critical role in codifying, setting standards, and monitoring human rights violations in the context of sexual and reproductive health and rights. In recent years, these institutions have developed and applied human rights standards in the more particular context of maternal mortality and morbidity, and have increasingly recognized a critical human rights issue in the provision and experience of care during and after pregnancy, including during childbirth. However, the international human rights standards on mistreatment during facility-based childbirth remain, in an early stage of development, focused largely on a discrete subset of experiences, such as forced sterilization and lack of access to emergency obstetric care. As a consequence, the range of mistreatment that women may experience has not been adequately addressed or analyzed under international human rights law. Identifying human rights norms and standards related to the full range of documented mistreatment is thus a first step towards addressing violations of human rights during facility-based childbirth, ensuring respectful and humane treatment, and developing a program of work to improve the overall quality of maternal care. This article reviews international human rights standards related to the mistreatment of women during childbirth in facility settings under regional and international human rights law and lays out an agenda for further research and action. PMID:28559681

  2. 26 CFR 1.892-6T - Income of international organizations (temporary regulations).

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Income of international organizations (temporary... International Organizations Immunities Act (22 U.S.C. 288) (the provisions of which are set forth in paragraph (b)(3) of § 1.893-1), the income of an international organization (as defined in section...

  3. 26 CFR 1.893-1 - Compensation of employees of foreign governments or international organizations.

    Science.gov (United States)

    2010-04-01

    ... or international organizations. 1.893-1 Section 1.893-1 Internal Revenue INTERNAL REVENUE SERVICE... Compensation of employees of foreign governments or international organizations. (a) Employees of foreign...) Employees of international organizations—(1) Exempt from tax. Except to the extent that the exemption...

  4. Crimes against humanity: the role of international courts.

    Directory of Open Access Journals (Sweden)

    Eder Milton Schneider

    Full Text Available We study the role of international tribunals, like the International Criminal Court (ICC, as an effective way of reducing the number and/or gravity of crimes against humanity. The action of the ICC is directed against leaders that promote or tolerate these kinds of crimes, that is, political authorities, army commanders, civil leaders, etc. In order to simulate the action of the ICC we build a hierarchical society where the most important leaders have the highest connectivity and can spread their points of view, or their orders, through a chain of less but still highly connected deputy chiefs or opinion chieftains. In this way, if they practice misconduct, corruption, or any kind of discriminatory or criminal actions against individuals or groups, it would very difficult and improbable that they will be prosecuted by the courts of their own country. It is to alleviate this situation that the ICC was created. Its mission is to process and condemn crimes against humanity though a supranational organism that can act on criminal leaders in any country. In this study, the action of the ICC is simulated by removing the corrupt leader and replacing it by a "decent" one. However, as the action of the corrupt leader could have spread among the population by the time the ICC acts, we try to determine if a unique action of the ICC is sufficient or if further actions are required, depending on the degree of deterioration of the human rights in the hypothetical country. The results evidence the positive effect of the ICC action with a relatively low number of interventions. The effect of the ICC is also compared with the action of the local national judiciary system.

  5. Crimes against humanity: the role of international courts.

    Science.gov (United States)

    Schneider, Eder Milton; Iglesias, José Roberto; Hallberg, Karen; Kuperman, Marcelo Néstor

    2014-01-01

    We study the role of international tribunals, like the International Criminal Court (ICC), as an effective way of reducing the number and/or gravity of crimes against humanity. The action of the ICC is directed against leaders that promote or tolerate these kinds of crimes, that is, political authorities, army commanders, civil leaders, etc. In order to simulate the action of the ICC we build a hierarchical society where the most important leaders have the highest connectivity and can spread their points of view, or their orders, through a chain of less but still highly connected deputy chiefs or opinion chieftains. In this way, if they practice misconduct, corruption, or any kind of discriminatory or criminal actions against individuals or groups, it would very difficult and improbable that they will be prosecuted by the courts of their own country. It is to alleviate this situation that the ICC was created. Its mission is to process and condemn crimes against humanity though a supranational organism that can act on criminal leaders in any country. In this study, the action of the ICC is simulated by removing the corrupt leader and replacing it by a "decent" one. However, as the action of the corrupt leader could have spread among the population by the time the ICC acts, we try to determine if a unique action of the ICC is sufficient or if further actions are required, depending on the degree of deterioration of the human rights in the hypothetical country. The results evidence the positive effect of the ICC action with a relatively low number of interventions. The effect of the ICC is also compared with the action of the local national judiciary system.

  6. Internal structure analysis of particle-double network gels used in a gel organ replica

    Science.gov (United States)

    Abe, Mei; Arai, Masanori; Saito, Azusa; Sakai, Kazuyuki; Kawakami, Masaru; Furukawa, Hidemitsu

    2016-04-01

    In recent years, the fabrication of patient organ replicas using 3D printers has been attracting a great deal of attention in medical fields. However, the cost of these organ replicas is very high as it is necessary to employ very expensive 3D printers and printing materials. Here we present a new gel organ replica, of human kidney, fabricated with a conventional molding technique, using a particle-double network hydrogel (P-DN gel). The replica is transparent and has the feel of a real kidney. It is expected that gel organ replicas produced this way will be a useful tool for the education of trainee surgeons and clinical ultrasonography technologists. In addition to developing a gel organ replica, the internal structure of the P-DN gel used is also discussed. Because the P-DN gel has a complex structure comprised of two different types of network, it has not been possible to investigate them internally in detail. Gels have an inhomogeneous network structure. If it is able to get a more uniform structure, it is considered that this would lead to higher strength in the gel. In the present study we investigate the structure of P-DN gel, using the gel organ replica. We investigated the internal structure of P-DN gel using Scanning Microscopic Light Scattering (SMILS), a non-contacting and non-destructive.

  7. From organized internal traffic to collective navigation of bacterial swarms

    Science.gov (United States)

    Ariel, Gil; Shklarsh, Adi; Kalisman, Oren; Ingham, Colin; Ben-Jacob, Eshel

    2013-12-01

    Bacterial swarming resulting in collective navigation over surfaces provides a valuable example of cooperative colonization of new territories. The social bacterium Paenibacillus vortex exhibits successful and diverse swarming strategies. When grown on hard agar surfaces with peptone, P. vortex develops complex colonies of vortices (rotating bacterial aggregates). In contrast, during growth on Mueller-Hinton broth gelled into a soft agar surface, a new strategy of multi-level organization is revealed: the colonies are organized into a special network of swarms (or ‘snakes’ of a fraction of millimeter in width) with intricate internal traffic. More specifically, cell movement is organized in two or three lanes of bacteria traveling between the back and the front of the swarm. This special form of cellular logistics suggests new methods in which bacteria can share resources and risk while searching for food or migrating into new territories. While the vortices-based organization on hard agar surfaces has been modeled before, here, we introduce a new multi-agent bacterial swarming model devised to capture the swarms-based organization on soft surfaces. We test two putative generic mechanisms that may underlie the observed swarming logistics: (i) chemo-activated taxis in response to chemical cues and (ii) special align-and-push interactions between the bacteria and the boundary of the layer of lubricant collectively generated by the swarming bacteria. Using realistic parameters, the model captures the observed phenomena with semi-quantitative agreement in terms of the velocity as well as the dynamics of the swarm and its envelope. This agreement implies that the bacteria interactions with the swarm boundary play a crucial role in mediating the interplay between the collective movement of the swarm and the internal traffic dynamics.

  8. 7th International Conference on Knowledge Management in Organizations (KMO)

    CERN Document Server

    Herrera, Francisco; Pérez, Javier; Rodríguez, Juan; 7th International Conference on Knowledge Management in Organizations: Service and Cloud Computing

    2013-01-01

    The seventh International Conference on Knowledge Management in Organizations (KMO) brings together researchers and developers from industry and the academic world to report on the latest scientific and technical advances on knowledge management in organisations.   KMO 2012 provides an international forum for authors to present and discuss research focused on the role of knowledge management for innovative services in industries, to shed light on recent advances in cloud computing for KM as well as to identify future directions for researching the role of knowledge management in service innovation and how cloud computing can be used to address many of the issues currently facing KM in academia and industrial sectors. The conference took place at Salamanca in Spain on the 11th-13th July in 2012.

  9. The challenges of organizing an international course in Latin America

    Directory of Open Access Journals (Sweden)

    Filippo Vairo

    2014-01-01

    Full Text Available The Latin American School of Human and Medical Genetics (ELAG is the main course of its kind in the genetics field in Latin America. Here we describe the main challenges regarding the organization of such event, including how we obtain funding and how we proceed with student selection. Thus, we aim to share our experience with other groups that intend to follow this format to create similar events in other areas in this region of the world.

  10. International Human Rights Mechanism and Construction of Harmonious Human Rights Relations

    Institute of Scientific and Technical Information of China (English)

    LIU JIE

    2007-01-01

    @@ The international human rights mechanism is a product of the pursuit for peace and justice of the human society. As the core values of the international human rights mechanism, the universal human rights standards provide the international community with a basic path of human rights development in different countries. In recent years a limited few of countries have utilized the universal human rights standards to promote their own strategic wills, and interfere in the sovereignty and domestic affairs of other countries with the excuse of human rights.However, the establishment and improvement of the human rights mechanism provide an institutional mode and path for the promotion of equality, dialog, and cooperation in the human rights issues of all countries. In addition, the establishment and improvement of the human rights mechanism also benefit the construction of harmonious human rights relations in a faster pace on the precondition of respect for national sovereignty by the international community.

  11. The changing role of health-oriented international organizations and nongovernmental organizations.

    Science.gov (United States)

    Okma, Kieke G H; Kay, Adrian; Hockenberry, Shelby; Liu, Joanne; Watkins, Susan

    2016-10-01

    Apart from governments, there are many other actors active in the health policy arena, including a wide array of international organizations (IOs), public-private partnerships and non-governmental organizations (NGOs) that state as their main mission to improve the health of (low-income) populations of low-income countries. Despite the steady rise in numbers and prominence of NGOs, however, there is lack of empirical knowledge about their functioning in the international policy arena, and most studies focus on the larger organizations. This has also caused a somewhat narrow focus of theoretical studies. Some scholars applied the 'principal-agent' theory to study the origins of IOs, for example, other focus on changing power relations. Most of those studies implicitly assume that IOs, public-private partnerships and large NGOs act as unified and rational actors, ignoring internal fragmentation and external pressure to change directions. We assert that the classic analytical instruments for understanding the shaping and outcome of public policy: ideas, interests and institutions apply well to the study of IOs. As we will show, changing ideas about the proper role of state and non-state actors, changing positions and activities of major stakeholders in the (international) health policy arena, and shifts in political institutions that channel the voice of diverging interests resulted in (and reflected) the changing positions of the health-oriented organizations-and also affect their future outlook. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  12. Teaching International Law: Concepts in International Relations

    Science.gov (United States)

    Starbird, Caroline; Pettit, Jenny; Singleton, Laurel

    2004-01-01

    This book is designed to introduce students to public international law. Topics covered include international public organizations, such as the United Nations and World Trade Organization, international courts, international human rights law, international trade law, and international environmental law. The goal of each study is to examine how…

  13. Determinants of human resource investment in internal controls

    National Research Council Canada - National Science Library

    Jong-Hag Choi Joonil Lee Catherine Heyjung Sonu

    2013-01-01

    Using the unique reporting environment in Korea, this study investigates the determinants of human resource investment in internal controls for 1352 listed firms disclosing the number of personnel who...

  14. AFRREV IJAH: An International Journal of Arts and Humanities - Vol ...

    African Journals Online (AJOL)

    PROMOTING ACCESS TO AFRICAN RESEARCH ... AFRREV IJAH: An International Journal of Arts and Humanities - Vol 6, No 2 (2017) ... Taylor and Francis Journals under the critical lens of readability analysis ... Current Issue Atom logo

  15. The role of international humanitarian organizations of the western Balkans: Serbia case

    Directory of Open Access Journals (Sweden)

    Stajić Ljubomir

    2013-01-01

    Full Text Available The Western Balkans in the period from 1992 to 2000 and later was the site of serious armed conflicts in which there was a significant threat to human life and other human rights of the civilian population. The deployment of international humanitarian organizations in this area was significant and with somewhat different role than the example of the African continent or elsewhere. Period of the ten war years as many post-war years of their engagement was quite enough for methodologically correct examination of their role, problems and attitudes of the 'beneficiaries' of these organizations on the activities of these organizations and their synchronization with the government. Numerous problems were noted from the practice of humanitarian organizations that are potentially useful for improvements in the future. In this paper we present only some parts of the expert group from Serbia extensive research who exactly talking about these problems. Particularly interesting are the data on the abuse of humanitarian aid as well as data that are different from those presented by some official international organizations.

  16. [Organ transplantation and human dignity. Editorial].

    Science.gov (United States)

    Bardenheuer, H J; Kupatt, C; Anselm, R

    1994-08-01

    Modern medicine has succeeded in achieving enormous technical developments. One recent highlight has been the introduction of postmortem organ transplantation. At the same time, serious objections have been raised concerning the radical changes in the cultural conception of the inviolable body. One major objection arises from the conflict of considering a brain-dead person as dead. The presence of brain death is a prerequisite for post-mortem organ donation, because only during this phase of dying does the individual quality as dead while the organs, other than the brain, remain viable. The objection implies scepticism as to the physician's ability to distinguish a dead from a living person. On the other hand, even the critics must rely on the physician's ability to discriminate, e.g., when to discontinue resuscitation. The medical community has not found reasons to restrict the definition of irreversible coma 25 years after its first formulation. It must be clearly recognised that reasons other than medical ones can be decisive for refusing organ donation. One ethical problem is the therapeutic benefit of organ transplantation. The beneficiary of the treatment is not the donor, but another person, the recipient. The concept of human dignity does not allow the use of a person for purposes other than the ones he/she consents to, as Immanual Kant stated. Although the human corpse is not a person in the full sense, even if it is protected by the thought of respect for the former person, the life-interest of the organ recipient had to be considered legitimate.(ABSTRACT TRUNCATED AT 250 WORDS)

  17. International Human Resource Management: A Review from Pakistani Perspective

    OpenAIRE

    Shah, Syed Tanveer Hussain; Jamil, Raja Ahmed; Shah, Tazeem Ali; Kazmi, Zain

    2014-01-01

    This article provides information about the International Human Resource Management and discusses HRM according to the international prospective in Pakistan. In this article it is discussed that how environmental and cultural factors affect the recruitment, selection and industry/employee relation in Pakistan. In the end some conclusions are made in reference to the context.

  18. International Human Resource Management: A Review from Pakistani Perspective

    OpenAIRE

    Shah, Syed Tanveer Hussain; Jamil, Raja Ahmed; Shah, Tazeem Ali; Kazmi, Zain

    2014-01-01

    This article provides information about the International Human Resource Management and discusses HRM according to the international prospective in Pakistan. In this article it is discussed that how environmental and cultural factors affect the recruitment, selection and industry/employee relation in Pakistan. In the end some conclusions are made in reference to the context.

  19. 78 FR 44959 - Public Workshop Related to the International Maritime Organization's Development of a Mandatory...

    Science.gov (United States)

    2013-07-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard Public Workshop Related to the International Maritime Organization's Development of a... International Maritime Organization (IMO Polar Code). Various safety topics will be discussed including...

  20. The Role Of Soft Law Acts In The Mechanism Of Functioning Of International Organizations

    OpenAIRE

    2014-01-01

    Present article focuses on the norms of soft law in the framework of international organizations. Today majority of scientists become an interesting phenomenon decision of international organizations which are increasingly sound as a category of "soft law" and its influence on the development of international law in general. International organizations cease to be the "second" subject of international law, and if you have not won the first place, it is only a matter of time. In the article th...

  1. Human Work Interaction Design Meets International Development

    DEFF Research Database (Denmark)

    Campos, Pedro; Clemmensen, Torkil; Barricelli, Barbara Rita

    2017-01-01

    Over the last decade, empirical relationships between work domain analysis and HCI design have been identified by much research in the field of Human Work Interaction Design (HWID) across five continents. Since this workshop takes place at the Interact Conference in Mumbai, there is a unique oppo...

  2. 48 CFR 245.302 - Contracts with foreign governments or international organizations.

    Science.gov (United States)

    2010-10-01

    ... governments or international organizations. 245.302 Section 245.302 Federal Acquisition Regulations System... international organizations. (1) General. (i) Approval. A contractor may use Government property on work for foreign governments and international organizations only when approved in writing by the...

  3. 48 CFR 45.302 - Contracts with foreign governments or international organizations.

    Science.gov (United States)

    2010-10-01

    ... governments or international organizations. 45.302 Section 45.302 Federal Acquisition Regulations System... Government Property 45.302 Contracts with foreign governments or international organizations. Requests by, or for the benefit of, foreign Governments or international organizations to use Government...

  4. 28 CFR 5.303 - Exemption available to persons accredited to international organizations.

    Science.gov (United States)

    2010-07-01

    ... to international organizations. 5.303 Section 5.303 Judicial Administration DEPARTMENT OF JUSTICE... to persons accredited to international organizations. Persons designated by foreign governments as their representatives in or to an international organization, other than nationals of the United...

  5. 29 CFR 452.27 - National, international organizations, and intermediate bodies.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false National, international organizations, and intermediate..., international organizations, and intermediate bodies. The officers of a national or international labor organization or of an intermediate body must be elected either directly by secret ballot among the members...

  6. 19 CFR 148.89 - Property of public international organizations and foreign governments.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Property of public international organizations and... Personnel of Foreign Governments and International Organizations and Special Treatment for Returning Individuals § 148.89 Property of public international organizations and foreign governments. (a)...

  7. 48 CFR 1445.302 - Contracts with foreign governments or international organizations.

    Science.gov (United States)

    2010-10-01

    ... governments or international organizations. 1445.302 Section 1445.302 Federal Acquisition Regulations System... Government Property 1445.302 Contracts with foreign governments or international organizations. The HCA... governments or international organizations request use of Government production and research property...

  8. 48 CFR 3445.405 - Contracts with foreign governments or international organizations.

    Science.gov (United States)

    2010-10-01

    ... governments or international organizations. 3445.405 Section 3445.405 Federal Acquisition Regulations System... Rental of Government Property 3445.405 Contracts with foreign governments or international organizations. Requests by, or for the benefit of, foreign governments or international organizations to use ED...

  9. 26 CFR 31.3306(c)(16)-1 - Services in employ of international organization.

    Science.gov (United States)

    2010-04-01

    ... of 1954) § 31.3306(c)(16)-1 Services in employ of international organization. (a) Subject to the provisions of section 1 of the International Organizations Immunities Act (22 U.S.C. 228), services performed in the employ of an international organization as defined in section 7701(a)(18) are excepted...

  10. International organizations to enable world-wide mobile satellite services

    Science.gov (United States)

    Anglin, Richard L., Jr.

    1993-01-01

    Numbers of systems exist or have been proposed to provide world-wide mobile satellite services (MSS). Developers of these systems have formulated institutional structures they consider most appropriate for profitable delivery of these services. MSS systems provide niche services and complement traditional telecommunications networks; they are not integrated into world-wide networks. To be successful, MSS system operators must be able to provide an integrated suite of services to support the increasing globalization, interconnectivity, and mobility of business. The critical issue to enabling 'universal roaming' is securing authority to provide MSS in all of the nations of the world. Such authority must be secured in the context of evolving trends in international telecommunications, and must specifically address issues of standardization, regulation and organization. Today, only one existing organization has such world-wide authority. The question is how proponents of new MSS systems and services can gain similar authority. Securing the appropriate authorizations requires that these new organizations reflect the objectives of the nations in which services are to be delivered.

  11. Human Rights Education and the International Baccalaureate Diploma Programme

    Science.gov (United States)

    Froman, Nica

    2015-01-01

    In 2003, the International Baccalaureate Diploma Programme (IBDP)--a program implemented in thousands of schools globally--introduced a human rights course (Makivirta, 2003). This curriculum is the first of its kind to hold potential widespread influence on human rights education in the formal education sector. In this study, I analyze the…

  12. The Netherlands and the Development of International Human Rights Instruments

    NARCIS (Netherlands)

    Reiding, H.

    2007-01-01

    When discussing the Netherlands' international human rights policies, the first aspects to come to mind are usually those related to how it addresses and reacts to concrete human rights violations by other countries. In fact, there sometimes appears to be a tendency for public opinion to identify a

  13. International human rights and cultural diversity: a balancing act

    NARCIS (Netherlands)

    Donders, Y.

    2013-01-01

    It is broadly agreed that international human rights law and cultural diversity have a mutually interdependent and beneficial relationship. Many human rights, such as the rights to freedom of expression, freedom of religion, freedom of assembly, as well as the rights to take part in cultural life an

  14. An International Urogynecological Association (IUGA) / International Continence Society (ICS) Joint Report on the Terminology for Female Pelvic Organ Prolapse (POP)

    NARCIS (Netherlands)

    Haylen, Bernard T; Maher, Christopher F; Barber, Matthew D; Camargo, Sérgio; Dandolu, Vani; Digesu, Alex; Goldman, Howard B; Huser, Martin; Milani, Alfredo L; Moran, Paul A; Schaer, Gabriel N; Withagen, Mariëlla I J

    2016-01-01

    INTRODUCTION: The terminology for female pelvic floor prolapse (POP) should be defined and organized in a clinically-based consensus Report. METHODS: This Report combines the input of members of two International Organizations, the International Urogynecological Association (IUGA) and the Internatio

  15. Driving Force to Socialize the International Norms of Human Rights

    Institute of Scientific and Technical Information of China (English)

    LIU BO

    2011-01-01

    Human rights,as a great term and lofty goal,have unquestionably become a topic of mainstream talk in the present-day world.2 Such mainstream talk has been internalized into part of the social structure.The current international society is experiencing a profound reorganization and transition in values.All kinds of new interactions under the context of globalization have resulted in the development of the current norms of international human rights,which are constructed on the basis of law and ethics.Therefore,analyzing the dynamic factors of socialization that support the operation of human rights norms in international society has become increasingly important in today's mutually dependent society.

  16. Workshop meeting report Organs-on-Chips: human disease models.

    Science.gov (United States)

    van de Stolpe, Anja; den Toonder, Jaap

    2013-09-21

    The concept of "Organs-on-Chips" has recently evolved and has been described as 3D (mini-) organs or tissues consisting of multiple and different cell types interacting with each other under closely controlled conditions, grown in a microfluidic chip, and mimicking the complex structures and cellular interactions in and between different cell types and organs in vivo, enabling the real time monitoring of cellular processes. In combination with the emerging iPSC (induced pluripotent stem cell) field this development offers unprecedented opportunities to develop human in vitro models for healthy and diseased organ tissues, enabling the investigation of fundamental mechanisms in disease development, drug toxicity screening, drug target discovery and drug development, and the replacement of animal testing. Capturing the genetic background of the iPSC donor in the organ or disease model carries the promise to move towards "in vitro clinical trials", reducing costs for drug development and furthering the concept of personalized medicine and companion diagnostics. During the Lorentz workshop (Leiden, September 2012) an international multidisciplinary group of experts discussed the current state of the art, available and emerging technologies, applications and how to proceed in the field. Organ-on-a-chip platform technologies are expected to revolutionize cell biology in general and drug development in particular.

  17. Nucleosome Organization in Human Embryonic Stem Cells.

    Directory of Open Access Journals (Sweden)

    Puya G Yazdi

    Full Text Available The fundamental repeating unit of eukaryotic chromatin is the nucleosome. Besides being involved in packaging DNA, nucleosome organization plays an important role in transcriptional regulation and cellular identity. Currently, there is much debate about the major determinants of the nucleosome architecture of a genome and its significance with little being known about its role in stem cells. To address these questions, we performed ultra-deep sequencing of nucleosomal DNA in two human embryonic stem cell lines and integrated our data with numerous epigenomic maps. Our analyses have revealed that the genome is a determinant of nucleosome organization with transcriptionally inactive regions characterized by a "ground state" of nucleosome profiles driven by underlying DNA sequences. DNA sequence preferences are associated with heterogeneous chromatin organization around transcription start sites. Transcription, histone modifications, and DNA methylation alter this "ground state" by having distinct effects on both nucleosome positioning and occupancy. As the transcriptional rate increases, nucleosomes become better positioned. Exons transcribed and included in the final spliced mRNA have distinct nucleosome profiles in comparison to exons not included at exon-exon junctions. Genes marked by the active modification H3K4m3 are characterized by lower nucleosome occupancy before the transcription start site compared to genes marked by the inactive modification H3K27m3, while bivalent domains, genes associated with both marks, lie exactly in the middle. Combinatorial patterns of epigenetic marks (chromatin states are associated with unique nucleosome profiles. Nucleosome organization varies around transcription factor binding in enhancers versus promoters. DNA methylation is associated with increasing nucleosome occupancy and different types of methylations have distinct location preferences within the nucleosome core particle. Finally, computational

  18. Nucleosome Organization in Human Embryonic Stem Cells.

    Science.gov (United States)

    Yazdi, Puya G; Pedersen, Brian A; Taylor, Jared F; Khattab, Omar S; Chen, Yu-Han; Chen, Yumay; Jacobsen, Steven E; Wang, Ping H

    2015-01-01

    The fundamental repeating unit of eukaryotic chromatin is the nucleosome. Besides being involved in packaging DNA, nucleosome organization plays an important role in transcriptional regulation and cellular identity. Currently, there is much debate about the major determinants of the nucleosome architecture of a genome and its significance with little being known about its role in stem cells. To address these questions, we performed ultra-deep sequencing of nucleosomal DNA in two human embryonic stem cell lines and integrated our data with numerous epigenomic maps. Our analyses have revealed that the genome is a determinant of nucleosome organization with transcriptionally inactive regions characterized by a "ground state" of nucleosome profiles driven by underlying DNA sequences. DNA sequence preferences are associated with heterogeneous chromatin organization around transcription start sites. Transcription, histone modifications, and DNA methylation alter this "ground state" by having distinct effects on both nucleosome positioning and occupancy. As the transcriptional rate increases, nucleosomes become better positioned. Exons transcribed and included in the final spliced mRNA have distinct nucleosome profiles in comparison to exons not included at exon-exon junctions. Genes marked by the active modification H3K4m3 are characterized by lower nucleosome occupancy before the transcription start site compared to genes marked by the inactive modification H3K27m3, while bivalent domains, genes associated with both marks, lie exactly in the middle. Combinatorial patterns of epigenetic marks (chromatin states) are associated with unique nucleosome profiles. Nucleosome organization varies around transcription factor binding in enhancers versus promoters. DNA methylation is associated with increasing nucleosome occupancy and different types of methylations have distinct location preferences within the nucleosome core particle. Finally, computational analysis of nucleosome

  19. International Human Trafficking: Measuring Clandestinity by the Structural Equation Approach

    Directory of Open Access Journals (Sweden)

    Alexandra Rudolph

    2017-06-01

    Full Text Available Worldwide human trafficking is the third most often registered international criminal activity, ranked only after drug and weapon trafficking. This article focusses on three questions: 1 How can human trafficking be measured? 2 What are the causes and indicators of this criminal activity which exploits individuals? 3 Which countries observe a high (or low level of human trafficking inflow? We apply the Multiple Indicators Multiple Causes structural equation model to measure human trafficking inflows in a way which includes all potential causes and indicators in one estimation model. The human trafficking measurement focusses on international human trafficking. We use freely available existing data and thus generate an objective measure of the extent of trafficking. Countries are ranked according to their potential to be a destination country based on various characteristics of the trafficking process.

  20. Selenium in human male reproductive organs.

    Science.gov (United States)

    Oldereid, N B; Thomassen, Y; Purvis, K

    1998-08-01

    The objective of the study was to obtain information on the concentration and distribution of selenium throughout the human male reproductive tract. Material was removed at autopsy from 41 men who had died suddenly and unexpectedly. Semen samples were also provided from 184 men attending an andrology clinic for fertility investigation and from 32 healthy volunteers. Significant positive correlations in the selenium concentration were demonstrated between the different reproductive organs, the testis having the highest concentrations. No correlation was found between the concentration of selenium in the genital organs and liver, kidney or blood, suggesting that its uptake and/or biochemical activity in the reproductive organs may be controlled by similar mechanisms not shared by the other organs. No significant age-dependent changes could be detected in tissue selenium concentrations. In a group of men under fertility investigation, a significant positive correlation was obtained between seminal plasma concentrations of selenium and concentrations of spermatozoa in the same ejaculate. A significant positive correlation between concentrations of zinc and selenium in the same ejaculates indicated that selenium may arise largely from the prostate gland.

  1. International language management and diversity climate in multicultural organizations

    DEFF Research Database (Denmark)

    Lauring, Jakob; Selmer, Jan

    2012-01-01

    to internationalization is how to develop and support an environment that is tolerant of the diversity which exists in multicultural organizations. Based on questionnaire responses from 489 members of academic multicultural departments, we examined the relation between the management of a common language and a positive......Increasing globalization has made the use and management of language a vital element of engaging in international business activities. Despite this fact, empirical surveys with many respondents examining language management are extremely rare. Another equally important issue related...... diversity climate. Results showed that consistency in English management communication had strong positive relationships with all of the four investigated diversity climate variables; openness to linguistic, visible, value, and informational diversity. English communication consistency had a positive...

  2. REGULATING DOMESTIC WORK BY THE INTERNATIONAL LABOUR ORGANIZATION

    Directory of Open Access Journals (Sweden)

    Alina Paula LARION

    2014-06-01

    Full Text Available Housework or domestic work is the work performed in the interest for one or more households. Convention No.189/2011 and Recommendation of domestic workers no.201/2011 were adopted in the framework of the 100th session of the International Labour Organization Conference. These regulations provided detailed and constructive orientations on how to regulate a category of workers who need support. This document presents some aspects of domestic workers rights provided by Convention no. 189 and Recommendation No. 201. Thus, we will talk about the rights of domestic workers regarding salary, hours off, social protection, health and safety at work, and what are the measures which should be adopted by states which ratify this Convention.

  3. Functional network organization of the human brain.

    Science.gov (United States)

    Power, Jonathan D; Cohen, Alexander L; Nelson, Steven M; Wig, Gagan S; Barnes, Kelly Anne; Church, Jessica A; Vogel, Alecia C; Laumann, Timothy O; Miezin, Fran M; Schlaggar, Bradley L; Petersen, Steven E

    2011-11-17

    Real-world complex systems may be mathematically modeled as graphs, revealing properties of the system. Here we study graphs of functional brain organization in healthy adults using resting state functional connectivity MRI. We propose two novel brain-wide graphs, one of 264 putative functional areas, the other a modification of voxelwise networks that eliminates potentially artificial short-distance relationships. These graphs contain many subgraphs in good agreement with known functional brain systems. Other subgraphs lack established functional identities; we suggest possible functional characteristics for these subgraphs. Further, graph measures of the areal network indicate that the default mode subgraph shares network properties with sensory and motor subgraphs: it is internally integrated but isolated from other subgraphs, much like a "processing" system. The modified voxelwise graph also reveals spatial motifs in the patterning of systems across the cortex.

  4. 49 CFR 604.7 - Qualified human service organizations.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Qualified human service organizations. 604.7... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CHARTER SERVICE Exceptions § 604.7 Qualified human service organizations. (a) A recipient may provide charter service to a qualified human service organization (QHSO)...

  5. Labor rights as legal constitutional category – Kosovo in relation to international labor organization

    Directory of Open Access Journals (Sweden)

    Muhamet Vokrri

    2015-11-01

    Full Text Available The purpose of this study paper is the analyzing of the processes that followed the labor relations, its historical development respectively, since its first concrete efforts from the representatives of the workers (unions till the establishment of the International Labor Organization (1919. As it is known the labor law presents one of the fundamental rights of the human being, thus such rights (right to work, freedom of work are constitutional category and protected in whole legal systems of the present time. The efforts to install such positive spirit were not easy. Genuinely is known that bearers of progressive developments in this field (end of XIX century were organized groups of workers (unions, then initiatives from various statesmen and later to be materialized from the governments of present time followed by the addressing and protecting of these rights in international aspect. Practice has proved that creation, purpose and activity of International Labor Organization has provided its benefits in achieving the primary principles of work, such rights proclaimed by the majority of world states and embedded in their highest legal act (Constitution of the organization in question (ILO. We consider that bearers of government politics of Kosovo, responsible sectors of this field respectively, shall regard these rules set and implemented by this international body and at the same time make maximal efforts towards advancing the current legislation in this field as well as to utilize all necessary resources in order to achieve the vital goal which is the adherence in ILO. This would certainly have an impact on minimizing the occurrence of eventual discontent from the organized groups (Unions as well as other classes and naturally the progress and positive effects in this field would be visible and useful for the society.

  6. Internal mixing of the organic aerosol by gas phase diffusion of semivolatile organic compounds

    Directory of Open Access Journals (Sweden)

    C. Marcolli

    2004-01-01

    Full Text Available This paper shows that most of the so far identified constituents of the tropospheric organic particulate matter belong to a semivolatile fraction for which gas phase diffusion in the lower troposphere is sufficiently fast to establish thermodynamic equilibrium between aerosol particles. For the first time analytical expressions for this process are derived. Inspection of vapor pressure data of a series of organic substances allows a rough estimate for which substances this mixing process must be considered. As general benchmarks we conclude that for typical aerosol radii between 0.1 and 1 µm this mixing process is efficient at 25°C for polar species with molecular weights up to 200 and for non-polar species up to 320. At −10°C, these values are shifted to 150 for polar and to 270 for non-polar substances. The extent of mixing of this semivolatile fraction is governed by equilibrium thermodynamics, leading to a selectively, though not completely, internally mixed aerosol. The internal mixing leads to a systematic depression of melting and deliquescence points of organic and mixed organic/inorganic aerosols, thus leading to an aerosol population in the lower troposphere which is predominantly liquid.

  7. The Influence of Human Resource Practices on Internal Customer Satisfaction and Organizational Effectiveness

    Directory of Open Access Journals (Sweden)

    IRFAN ULLAH

    2013-08-01

    Full Text Available It is generally believed that the impact of Human Resource Practices on internal customer satisfaction can create comparative advantage for the organizational performance. The main objective of this study was to find out the impact of Human Resource Practices on internal customer satisfaction and organizational effectiveness. The impact of human resource practices on the overall performance of organizations has been a leading subject of research and the results havebeen encouraging, indicative of positive relationship between Human Resource practices and organizational effectiveness. Data was collected through personally administered questionnaire-based survey from 290 banking personnel of Pakistan. Structural equation modeling was used to examine the anticipated model. The results showed that some Human Resource Practices appear to be linked to internal customer satisfaction and organizational effectiveness. The implications for practitioners were to modify and emphasize certain human resource practices, and to emphasize the role of internal customers for organizational effectiveness enhancement. These findings revealed the importance of internal customers in enhancing employee morale, organizational commitment, employee productivity, turnover rate and the organization’s ability to attract talent.

  8. The Influence of Human Resource Practices on Internal Customer Satisfaction and Organizational Effectiveness

    Directory of Open Access Journals (Sweden)

    Irfan Ullah

    2013-08-01

    Full Text Available It is generally believed that the impact of Human Resource Practices on internal customer satisfaction can create comparative advantage for the organizational performance. The main objective of this study was to find out the impact of Human Resource Practices on internal customer satisfaction and organizational effectiveness. The impact of human resource practices on the overall performance of organizations has been a leading subject of research and the results have been encouraging, indicative of positive relationship between Human Resource practices and organizational effectiveness. Data was collected through personally administered questionnaire-based survey from 290 banking personnel of Pakistan. Structural equation modeling was used to examine the anticipated model. The results showed that some Human Resource Practices appear to be linked to internal customer satisfaction and organizational effectiveness. The implications for practitioners were to modify and emphasize certain human resource practices, and to emphasize the role of internal customers for organizational effectiveness enhancement. These findings revealed the importance of internal customers in enhancing employee morale, organizational commitment, employee productivity, turnover rate and the organization’s ability to attract talent.

  9. Direct determination of internal radiation dose in human blood

    OpenAIRE

    Tanır, Ayse Güneş; Güleç, Özge

    2014-01-01

    The purpose of this study is to measure the internal radiation dose using a human blood sample. In the literature, there is no process that allows the direct measurement of the internal radiation dose received by a person. The luminescence counts from a blood sample having a laboratory-injected radiation dose and the waste blood of the patient injected with a radiopharmaceutical for diagnostic purposes were both measured. The decay and dose-response curves were plotted for the different doses...

  10. Repatriation of human remains following death in international travellers.

    Science.gov (United States)

    Connolly, Ruairi; Prendiville, Richard; Cusack, Denis; Flaherty, Gerard

    2017-03-01

    Death during international travel and the repatriation of human remains to one's home country is a distressing and expensive process. Much organization is required involving close liaison between various agencies. A review of the literature was conducted using the PubMed database. Search terms included: 'repatriation of remains', 'death', 'abroad', 'tourism', 'travel', 'travellers', 'travelling' and 'repatriation'. Additional articles were obtained from grey literature sources and reference lists. The local national embassy, travel insurance broker and tour operator are important sources of information to facilitate the repatriation of the deceased traveller. Formal identification of the deceased's remains is required and a funeral director must be appointed. Following this, the coroner in the country or jurisdiction receiving the repatriated remains will require a number of documents prior to providing clearance for burial. Costs involved in repatriating remains must be borne by the family of the deceased although travel insurance may help defray some of the costs. If the death is secondary to an infectious disease, cremation at the site of death is preferred. No standardized procedure is in place to deal with the remains of a migrant's body at present and these remains are often not repatriated to their country of origin. Repatriation of human remains is a difficult task which is emotionally challenging for the bereaving family and friends. As a travel medicine practitioner, it is prudent to discuss all eventualities, including the risk of death, during the pre-travel consultation. Awareness of the procedures involved in this process may ease the burden on the grieving family at a difficult time.

  11. Human Dignity in International Law: Issues and Challenges

    Directory of Open Access Journals (Sweden)

    Izabela Bratiloveanu

    2012-05-01

    Full Text Available We intend to present in this synthesis study the concept of human dignity, reviewing the main legalinstruments on the protection of human rights that defines it, concisely analysing the jurisprudence of theEuropean Court of Justice and of the European Court of Human Rights, focusing on the key moments of itsjurisprudential definition. Human dignity, through its continuously expending presence in international lawand through the controversies related to it, is an exciting and challenging topic of debate for Romanian andforeign literature, being one of the issues and challenges of the new millennium.

  12. RESHAPING ORGANIZATIONS – MANAGING PEOPLE THROUGH HR STRATEGIES AND INTERNAL MARKETING

    Directory of Open Access Journals (Sweden)

    Roxana Cioclov

    2014-10-01

    Full Text Available The following paper aims at presenting key concepts in regard to the interconnectivity between two similar and frequently confused practices – Human Resource Management and Internal Marketing. Therefore, it is intend to present both fields distinctively, in order to emphasise in the end the added value of the two working together. Given the fact that, in the specialised literature, there are different approaches on this subject and many questions raised regarding the separation of the instruments and particular objectives of the two practices, the paper presents a simplified approach on the HRM Cycle in comparison with the IM Cycle. Therefore, the paper is structured as follows: (1 HRM’s impact on the general activity of an organization – whether it is a manufacturing company or a service provider; (2 IM’s impact on the internal and external environment of the organization; (3 Analysis on the connection and in-/inter-/dependency of the two concepts and their meaning. Although HRM seems to bring numerous advantages to the organization, the current paper states that HR cannot be done at the same efficiency level in the absence of good Internal Marketing practices that allow the word - of - mouth to spread between the present and possible future employees. It is about a good branding that has to exceed the company’s geographical boundaries and to create the need, not only in terms of product consumer’s behavior, but also in regard to employees that want to be part of the brand.

  13. Attitude to the traditional knowledge of international governmental organizations and suggested strategies of China

    Directory of Open Access Journals (Sweden)

    Gong Cheng

    2012-07-01

    Full Text Available Traditional knowledge is an important issue for international governmental organizations (IGOs. A number of international conferences have been held to discuss this topic, and a number of relevant reports and resolutions have been produced. These resolutions reflect different interests at stake and express a different understanding and position towards traditional knowledge. IGOs led by the Convention on Biological Diversity focus more on environment and biodiversity, whereas IGOs including the World Intellectual Property Organization and World Trade Organization focus on economic development and international trade. Other IGOs such as the United Nations Declaration on the Rights of Indigenous Peoples focus on society and human rights. In consideration of China’s commitment to IGOs and rich history, China should attach moreimportance to the protection of traditional knowledge, and consider the initiation of legislation that provides the benefits of information sharing as described in the Nagoya Protocol. This will establish a benefit sharing system to protect traditional knowledge as a way to ensure harmonious development among the environment, economy, and society.

  14. Key points for developing an international declaration on nursing, human rights, human genetics and public health policy.

    Science.gov (United States)

    Anderson, G; Rorty, M V

    2001-05-01

    Human rights legislation pertaining to applications of human genetic science is still lacking at an international level. Three international human rights documents now serve as guidelines for countries wishing to develop such legislation. These were drafted and adopted by the United Nations Educational, Scientific and Cultural Organization, the Human Genome Organization, and the Council of Europe. It is critically important that the international nursing community makes known its philosophy and practice-based knowledge relating to ethics and human rights, and contributes to the globalization of genetics. Nurses have particular expertise because they serve in a unique role at grass roots level to mediate between genetic science and its application to public health policies and medical interventions. As a result, nurses worldwide need to focus a constant eye on human rights ideals and interpret these within social, cultural, economic and political contexts at national and local levels. The purpose of this article is to clarify and legitimate the need for an international declaration on nursing, human rights, human genetics and public health policy. Because nurses around the world are the professional workforce by which genetic health care services and genetic research protocols will be delivered in the twenty-first century, members of the discipline of nursing need to think globally while acting locally. Above all other disciplines involved in genetics, nursing is in a good position to articulate an expanded theory of ethics beyond the principled approach of biomedical ethics. Nursing is sensitive to cultural diversity and community values; it is sympathetic to and can introduce an ethic of caring and relational ethics that listen to and accommodate the needs of local people and their requirements for public health.

  15. Determinants of human resource investment in internal controls

    Directory of Open Access Journals (Sweden)

    Jong-Hag Choi

    2013-09-01

    Full Text Available Using the unique reporting environment in Korea, this study investigates the determinants of human resource investment in internal controls for 1352 listed firms disclosing the number of personnel who are in charge of internal control-related tasks (IC personnel from 2005 to 2008. We find that the number of IC personnel within a firm and several key departments increase with firm size, number of employees, complexity and for Chaebols, and decrease in rapidly growing firms. Additional analysis reveals that the factors influencing internal control systems have an accentuated effect on firms with relatively larger firm size.

  16. Determinants of human resource investment in internal controls

    Institute of Scientific and Technical Information of China (English)

    Jong-Hag; Choi; Joonil; Lee; Catherine; Heyjung; Sonu

    2013-01-01

    Using the unique reporting environment in Korea, this study investigates the determinants of human resource investment in internal controls for 1352 listed firms disclosing the number of personnel who are in charge of internal controlrelated tasks(IC personnel) from 2005 to 2008. We find that the number of IC personnel within a firm and several key departments increase with firm size,number of employees, complexity and for Chaebols, and decrease in rapidly growing firms. Additional analysis reveals that the factors influencing internal control systems have an accentuated effect on firms with relatively larger firm size.

  17. Creating human organs in chimaera pigs: an ethical source of immunocompatible organs?

    Science.gov (United States)

    Shaw, David; Dondorp, Wybo; Geijsen, Niels; de Wert, Guido

    2015-12-01

    New techniques in regenerative medicine may soon enable the creation of human organs inside animals using induced pluripotent stem cells. This technology has the potential to solve the organ scarcity problem by providing a limitless source of personalised organs for transplantation, but also raises several ethical issues, particularly concerning animal welfare, the 'human features' problem and human dignity.

  18. Tonotopic organization of human auditory association cortex.

    Science.gov (United States)

    Cansino, S; Williamson, S J; Karron, D

    1994-11-07

    Neuromagnetic studies of responses in human auditory association cortex for tone burst stimuli provide evidence for a tonotopic organization. The magnetic source image for the 100 ms component evoked by the onset of a tone is qualitatively similar to that of primary cortex, with responses lying deeper beneath the scalp for progressively higher tone frequencies. However, the tonotopic sequence of association cortex in three subjects is found largely within the superior temporal sulcus, although in the right hemisphere of one subject some sources may be closer to the inferior temporal sulcus. The locus of responses for individual subjects suggests a progression across the cortical surface that is approximately proportional to the logarithm of the tone frequency, as observed previously for primary cortex, with the span of 10 mm for each decade in frequency being comparable for the two areas.

  19. Teaching about Child Labor and International Human Rights. ERIC Digest.

    Science.gov (United States)

    Hamot, Gregory E.; Jensen, Elizabeth S.

    An estimated 246 million children between the ages of 5 and 17 work in the agricultural, industrial, and craft sectors worldwide. Approximately 180 million of these children work under the worst forms of child labor as defined by the International Labor Organization (2002). In spite of conventions and protocols designed to eradicate the worst…

  20. Organization of human hypothalamus in fetal development.

    Science.gov (United States)

    Koutcherov, Yuri; Mai, Jürgen K; Ashwell, Ken W S; Paxinos, George

    2002-05-13

    The organization of the human hypothalamus was studied in 33 brains aged from 9 weeks of gestation (w.g.) to newborn, using immunohistochemistry for parvalbumin, calbindin, calretinin, neuropeptide Y, neurophysin, growth-associated protein (GAP)-43, synaptophysin, and the glycoconjugate 3-fucosyl- N-acetyl-lactosamine. Developmental stages are described in relation to obstetric trimesters. The first trimester (morphogenetic periods 9-10 w.g. and 11-14 w.g.) is characterized by differentiating structures of the lateral hypothalamic zone, which give rise to the lateral hypothalamus (LH) and posterior hypothalamus. The PeF differentiates at 18 w.g. from LH neurons, which remain anchored in the perifornical position, whereas most of the LH cells are displaced laterally. A transient supramamillary nucleus was apparent at 14 w.g. but not after 16 w.g. As the ventromedial nucleus differentiated at 13-16 w.g., three principal parts, the ventrolateral part, the dorsomedial part, and the shell, were revealed by distribution of calbindin, calretinin, and GAP43 immunoreactivity. The second trimester (morphogenetic periods 15-17 w.g., 18-23 w.g., and 24-33 w.g.) is characterized by differentiation of the hypothalamic core, in which calbindin- positive neurons revealed the medial preoptic nucleus at 16 w.g. abutted laterally by the intermediate nucleus. The dorsomedial nucleus was clearly defined at 10 w.g. and consisted of compact and diffuse parts, an organization that was lost after 15 w.g. Differentiation of the medial mamillary body into lateral and medial was seen at 13-16 w.g. Late second trimester was marked by differentiation of periventricular zone structures, including suprachiasmatic, arcuate, and paraventricular nuclei. The subnuclear differentiation of these nuclei extends into the third trimester. The use of chemoarchitecture in the human fetus permitted the identification of interspecies nuclei homologies, which otherwise remain concealed in the cytoarchitecture.

  1. Human resources evaluation in a marketing organization

    Directory of Open Access Journals (Sweden)

    Gutić Dragutin

    2009-01-01

    Full Text Available This work is first of all part of authors' initiated thinking in which in a certain way they try to promote the idea and need to accept and develop the concept of human resources management by marketing managers. This work's subject matter deals with human resources evaluation in a marketing organization as an important and certain element of this management. A new approach with critical reference to the present state of theory and practice is explained, new solutions are offered and thorough, almost radical changes and turnarounds are supported. Marketing managers mostly reluctantly accept the evaluation system for their employees. They often say that this is not their basic job, that it unnecessarily and absurdly puts a burden on them, that it takes their time, or they think however that their goal is to increase sales, to extend the existing and enter new markets, to improve the relationship with buyers and consumers etc. Evaluation enables employees to understand clearly what they are expected and how their results will be evaluated. Each member of the organization wants to know and have feedback about his or her work. This assessment of his or her work is a basis for rewarding, job security, career development, promotion in the organization, improvement and professional training etc. Evaluation is not in the least easy and simple work. On the contrary, It is a matter of a very complicated work followed by many difficulties and different restrictions in practice. It is a fact that great part of failure and poor system lies in an approach systematically incomplete and taken for granted. The authors gave a thorough review of basic restrictions and difficulties that should be count on when evaluating the employees. They come from the evaluators themselves (marketing managers, unelaborated evaluation methodology, as well as insufficient and late information as a base for evaluation. Marketing managers efficiency evaluation is focused through

  2. Funcionalidade e incapacidade humana: explorando o escopo da classificação internacional da Organização Mundial da Saúde Human functioning and disability: exploring the scope of the World Health Organization's international classification

    Directory of Open Access Journals (Sweden)

    Rosana Ferreira Sampaio

    2009-03-01

    Full Text Available A produção teórica sobre incapacidade se apresenta dicotomizada nas perspectivas médica e social. O modelo biomédico foca a deficiência, doença ou anormalidade corporal e como esses fatores produzem incapacidade. A abordagem social sugere que o significado de deficiência e incapacidade emerge de contextos sociais e culturais específicos. A OMS criou a Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF, que traz um sistema de classificação e modelo teórico baseados na junção dos modelos médico e social e usa uma abordagem biopsicossocial para integrar as dimensões da saúde. Apesar da importância e atualidade da CIF, alguns conceitos foram pouco detalhados e justificados, podendo ocasionar interpretações distintas. Propõe-se com este ensaio descrever o modelo da CIF e analisar o alcance da teoria biopsicossocial para explorar a natureza relacional das categorias deficiência e incapacidade, bem como o caráter universal da proposta da OMS. Um dos aspectos mais positivos da CIF é trazer à baila a natureza interativa da incapacidade e a divisão do fenômeno em três dimensões, mostrando o grau de complexidade do processo de funcionalidade e incapacidade humana.The theoretical discussion on disability is dichotomized according to the medical and social perspectives. The biomedical model focuses on impairment, disease, or physical abnormality and how these factors produce disability. The social approach suggests that the meaning of disability and impairment emerges from specific social and cultural contexts. The WHO created the International Classification of Functioning, Disability and Health (ICF, with a classification system and theoretical model based on the combination of the medical and social models and using a biopsychosocial approach to integrate the health dimensions. Despite the importance and immediacy of the ICF, some concepts were insufficiently detailed and justified and could lead to

  3. Mechanisms of endothelium and internal organs dysfunction associated with exposure to cobalt chloride (experimental study

    Directory of Open Access Journals (Sweden)

    L.V. Gigolaeva

    2016-09-01

    Full Text Available Cobalt administration in the human body is a risk factor for developing pulmonary and cardiovascular health problems. In this paper we report the results of functional studies and biochemical mechanisms of endothelial dysfunction and pathology of internal organs in cobalt intoxication in experiment. System-organ nature of the activation of oxidative processes is identified according to the increase of MDA secondary product in erythrocytes and homogenates of internal organs as well as the participation of AOC imbalance in the development of lipid peroxidation, the peculiarities of the violations of NO release endothelial function and participation in this process of L-arginine and an analogue of endogenous inhibitor of expression eNOS -L–NC - arginine methyl ester (L-NAME or L-nitro-arginine-methilester with cobalt intoxication in conditions of activation of oxidative processes. Chronic cobalt intoxication in rats leads to the activation of oxidative processes, thus there is inhibition of superoxide dismutase activity and the concentration of catalase and ceruloplasmin increased. Cholesterol metabolism is disturbed, as well as impaired nitric oxide production and its bioavailability, which is accompanied by the change of the microcirculatory hemodynamics of the visceral organs. The evaluation of the internal organs’ functional state according to the activity of the Na+,K+-ATPase in homogenates is performed, as well as due to the activity of organ-specific and excretory enzymes in blood serum on the background of cobalt toxicity. The role of changes of cholesterol metabolism is established – as a risk factor of atherogenesis in violation of the bioavailability of nitric oxide. For the pathogenetic correction of violations we applied the method using the endogenous antioxidant coenzyme Q10 and regulators of the expression eNOS L-arginine, L-NAME and their combination with coenzyme Q10.

  4. 12 CFR 269.10 - Time for internal labor organization business, consultations and negotiations.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Time for internal labor organization business... § 269.10 Time for internal labor organization business, consultations and negotiations. Solicitation of... and representatives of a labor organization shall, whenever practicable, be conducted on official time...

  5. IMPROVEMENT OF THE METHODS OF INTERNAL CONTROL OF INVENTORIES IN AGRICULTURAL ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    Afanasenko A. N.

    2013-11-01

    Full Text Available The article considers the necessity of inventories for any organization. The fate of the organization depends on its management effectiveness and its financial position. The organizational peculiarities of internal control in the agricultural sphere have been studied and the ways of improvement of the organizational and methodological mechanisms have been offered for the internal control of inventories in agricultural organizations

  6. GENASIS national and international monitoring networks for persistent organic pollutants

    Science.gov (United States)

    Brabec, Karel; Dušek, Ladislav; Holoubek, Ivan; Hřebíček, Jiří; Kubásek, Miroslav; Urbánek, Jaroslav

    2010-05-01

    Persistent organic pollutants (POPs) remain in the centre of scientific attention due to their slow rates of degradation, their toxicity, and potential for both long-range transport and bioaccumulation in living organisms. This group of compounds covers large number of various chemicals from industrial products, such as polychlorinated biphenyls, etc. The GENASIS (Global Environmental Assessment and Information System) information system utilizes data from national and international monitoring networks to obtain as-complete-as-possible set of information and a representative picture of environmental contamination by persistent organic pollutants (POPs). There are data from two main datasets on POPs monitoring: 1.Integrated monitoring of POPs in Košetice Observatory (Czech Republic) which is a long term background site of the European Monitoring and Evaluation Programme (EMEP) for the Central Europe; the data reveals long term trends of POPs in all environmental matrices. The Observatory is the only one in Europe where POPs have been monitored not only in ambient air, but also in wet atmospheric deposition, surface waters, sediments, soil, mosses and needles (integrated monitoring). Consistent data since the year 1996 are available, earlier data (up to 1998) are burdened by high variability and high detection limits. 2.MONET network is ambient air monitoring activities in the Central and Eastern European region (CEEC), Central Asia, Africa and Pacific Islands driven by RECETOX as the Regional Centre of the Stockholm Convention for the region of Central and Eastern Europe under the common name of the MONET networks (MONitoring NETwork). For many of the participating countries these activities generated first data on the atmospheric levels of POPs. The MONET network uses new technologies of air passive sampling, which was developed, tested, and calibrated by RECETOX in cooperation with Environment Canada and Lancaster University, and was originally launched as a

  7. Biomedicine and international human rights law: in search of a global consensus.

    Science.gov (United States)

    Andorno, Roberto

    2002-01-01

    Global challenges raised by biomedical advances require global responses. Some international organizations have made significant efforts over the last few years to establish common standards that can be regarded as the beginning of an international biomedical law. One of the main features of this new legal discipline is the integration of its principles into a human rights framework. This strategy seems the most appropriate, given the role of "universal ethics" that human rights play in our world of philosophical pluralism. In addition to the general standards that are gradually being established, a widespread consensus exists on the urgency of preventing two specific procedures: human germ-line interventions and human reproductive cloning. PMID:12571724

  8. Toward a Hermeneutical Theory of International Human Rights Education

    Science.gov (United States)

    Al-Daraweesh, Fuad; Snauwaert, Dale T.

    2013-01-01

    The purpose of this essay is to articulate and defend the epistemological foundations of international human rights education from the perspective of a hermeneutical interpretive methodology. Fuad Al-Daraweesh and Dale Snauwaert argue here that this methodology potentially alleviates the challenges that face the cross-cultural implementation of…

  9. Toward a Hermeneutical Theory of International Human Rights Education

    Science.gov (United States)

    Al-Daraweesh, Fuad; Snauwaert, Dale T.

    2013-01-01

    The purpose of this essay is to articulate and defend the epistemological foundations of international human rights education from the perspective of a hermeneutical interpretive methodology. Fuad Al-Daraweesh and Dale Snauwaert argue here that this methodology potentially alleviates the challenges that face the cross-cultural implementation of…

  10. 75 FR 3950 - Self-Regulatory Organizations; International Securities Exchange, LLC; Order Approving Proposed...

    Science.gov (United States)

    2010-01-25

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Order Approving Proposed..., the International Securities Exchange, LLC (``ISE'' or ``Exchange'') filed with the Securities...

  11. 77 FR 4852 - Self-Regulatory Organizations; International Securities Exchange, LLC; Order Approving a Proposed...

    Science.gov (United States)

    2012-01-31

    ... From the Federal Register Online via the Government Publishing Office ] SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Order Approving a Proposed... International Securities Exchange, LLC (the ``Exchange'' or ``ISE'') filed with the Securities and...

  12. 76 FR 59472 - Self-Regulatory Organizations; International Securities Exchange, Inc., Order Granting Approval...

    Science.gov (United States)

    2011-09-26

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; International Securities Exchange, Inc., Order Granting Approval of... International Securities Exchange, LLC (the ``Exchange'' or the ``ISE'') filed with the Securities and...

  13. International Law and Human Rights: Trends concerning International Migrants and Refugees.

    Science.gov (United States)

    Goodwin-Gill, Guy S.

    1989-01-01

    Places migrants and refugees within the human rights context, contrasting inalienable rights with the demands of sovereignty, and juxtaposing the two in a context of existing and developing international standards. Shows how the law must evolve, responding coherently to contemporary problems, if the structure of rights is to be maintained.…

  14. International Law and Human Rights: Trends concerning International Migrants and Refugees.

    Science.gov (United States)

    Goodwin-Gill, Guy S.

    1989-01-01

    Places migrants and refugees within the human rights context, contrasting inalienable rights with the demands of sovereignty, and juxtaposing the two in a context of existing and developing international standards. Shows how the law must evolve, responding coherently to contemporary problems, if the structure of rights is to be maintained.…

  15. Quality Control Review of the Defense Finance and Accounting Service Internal Audit Organization

    Science.gov (United States)

    2014-12-01

    No. DODIG-2015-043 D E C E M B E R 1 , 2 0 1 4 Quality Control Review of the Defense Finance and Accounting Service Internal Audit Organization... FINANCE AND ACCOUNTING SERVICE SUBJECT: Quality Control Review of the Defense Finance and Accounting Service Internal Audit Organization (Report No...organization, Defense Finance and Accounting Service Office of Internal Review (DFAS IR), in effect for the period ended June 30, 2014. The generally

  16. Leading by example: the role of international trauma organizations in global trauma initiatives.

    Science.gov (United States)

    Leighton, Ross

    2014-01-01

    As road traffic fatalities have emerged among the leading global threats to human health and safety, there is an imminent need for the mobilization of large medical organizations and private companies. Collectively, these partnerships can have a tremendous impact on road traffic safety through garnering funding for important initiatives, lobbying governments for policy reforms, and implementing organizational frameworks that foster the transfer of health-care knowledge to optimize trauma care in developing countries. In particular, concerted efforts by major orthopaedic associations can directly enable overwhelmed health-care systems to improve upon their prehospital care, emergency triage systems, trauma care protocols, and rehabilitation programs. The "SIGN" and "Broken Earth" programs serve as prime examples of the powerful impact international trauma organizations can have on global trauma initiatives.

  17. The Impact of International Human Rights Law on International Criminal Procedure = De invloed van internationale mensenrechten op internationaal strafprocesrecht

    NARCIS (Netherlands)

    Zeegers, K.

    2013-01-01

    This article examines the impact of international human rights law on international criminal procedure. Given the fact that international criminal courts and tribunals (ICTs) are not party to human rights treaties, the question arises whether these norms formally even apply to them. The first part o

  18. The Impact of International Human Rights Law on International Criminal Procedure = De invloed van internationale mensenrechten op internationaal strafprocesrecht

    NARCIS (Netherlands)

    Zeegers, K.

    2013-01-01

    This article examines the impact of international human rights law on international criminal procedure. Given the fact that international criminal courts and tribunals (ICTs) are not party to human rights treaties, the question arises whether these norms formally even apply to them. The first part o

  19. The role of international organizations in the spread of genetically modified food

    Directory of Open Access Journals (Sweden)

    Papić-Brankov Tatjana

    2012-01-01

    Full Text Available Numerous international organizations on the direct or indirect way influence the diffusion of genetically modified (GM food. Particularly important role in this process play a World Bank (WB, World Trade Organization (WTO, Consultative Group for International Agricultural Research (CGIAR, the Organization for Food and Agriculture United Nations (FAO UN, various international foundations, universities and other scientific institutions. The paper concludes that taking in consideration, inequality of diffusion recognizing GM plant culture, ignoring the interests of poor farmers and countries, restrictions on technology transfer and general domination of the private sector, certain international organizations are trying to reconcile interest of multinational companies and the needs of the poor.

  20. Restoring America's Leadership through Scholarships for Undergraduates from Developing Countries: The Uniting Students in America (USA) Proposal. Joint Hearing before the Subcommittee on International Organizations, Human Rights, and Oversight of the Committee on Foreign Affairs and the Subcommittee on Higher Education, Lifelong Learning, and Competitiveness of the Committee on Education and Labor, House of Representatives, One Hundred Tenth Congress, Second Session (June 19, 2008). Serial Number 110-189 (Committee on Foreign Affairs). Serial Number 110-96 (Committee on the Education and Labor)

    Science.gov (United States)

    US House of Representatives, 2008

    2008-01-01

    This joint hearing follows a hearing focused on a report issued by the Subcommittee on International Organizations, Human Rights, and Oversight entitled, "The Decline in America's Reputation, Why?" based on a series of some 10 hearings. The report documented the dramatic decline in international approval for American leadership from historic…

  1. The state of the international organ trade: a provisional picture based on integration of available information.

    Science.gov (United States)

    Shimazono, Yosuke

    2007-12-01

    Organ transplantation is widely practised worldwide. The expansion of organ transplantation has led to a critical shortage of organs and the development of the organ trade. Many patients travel to areas where organs are obtainable through commercial transactions. Although the international organ trade is regarded as an important health policy issue, its current state remains obscure because of scarce data and the lack of efforts to synthesize available data. This paper is an attempt to integrate information about the current international organ trade and create a tentative global picture based on a systematic review of 309 media reports, journal articles and other documents. The international organ trade is described in terms of its forms, the organ-exporting countries, the organ-importing countries and its outcomes and consequences.

  2. 26 CFR 31.3401(a)(5)-1 - Remuneration for services for foreign government or international organization.

    Science.gov (United States)

    2010-04-01

    ... government or international organization. 31.3401(a)(5)-1 Section 31.3401(a)(5)-1 Internal Revenue INTERNAL....3401(a)(5)-1 Remuneration for services for foreign government or international organization. (a... are immaterial for purposes of the exception. (b) Services for international organization. (1)...

  3. Employing moderate resolution sensors in human rights and international humanitarian law monitoring

    Science.gov (United States)

    Marx, Andrew J.

    Organizations concerned with human rights are increasingly using remote sensing as a tool to improve their detection of human rights and international humanitarian law violations. However, as these organizations have transitioned to human rights monitoring campaigns conducted over large regions and extended periods of time, current methods of using fine- resolution sensors and manpower-intensive analyses have become cost- prohibitive. To support the continued growth of remote sensing in human rights and international humanitarian law monitoring campaigns, this study researches how moderate resolution land observatories can provide complementary data to operational human rights monitoring efforts. This study demonstrates the capacity of moderate resolutions to provide data to monitoring efforts by developing an approach that uses Landsat Enhanced Thematic Mapper Plus (ETM+) as part of a system for the detection of village destruction in Darfur, Sudan. Village destruction is an indicator of a human rights or international humanitarian law violations in Darfur during the 2004 study period. This analysis approach capitalizes on Landsat's historical archive and systematic observations by constructing a historic spectral baseline for each village in the study area that supports automated detection of a potentially destroyed village with each new overpass of the sensor. Using Landsat's near-infrared band, the approach demonstrates high levels of accuracy when compared with a U.S. government database documenting destroyed villages. This approach is then applied to the Darfur conflict from 2002 to 2008, providing new data on when and where villages were destroyed in this widespread and long-lasting conflict. This application to the duration of a real-world conflict illustrates the abilities and shortcomings of moderate resolution sensors in human rights monitoring efforts. This study demonstrates that moderate resolution satellites have the capacity to contribute

  4. Internal marketing: creating quality employee experiences in health care organizations.

    Science.gov (United States)

    Masri, Maysoun Dimachkie; Oetjen, Dawn; Rotarius, Timothy

    2011-01-01

    To cope with the recent challenges within the health care industry, health care managers need to engage in the internal marketing of their various services. Internal marketing has been used as an effective management tool to increase employees' motivation, satisfaction, and productivity (J Mark Commun. 2010;16(5):325-344). Health care managers should understand that an intense focus on internal marketing factors will lead to a quality experience for employees that will ultimately have a positive effect on the patient experiences.

  5. Human resource management in the project-oriented organization

    NARCIS (Netherlands)

    J.R. Turner; M. Huemann; A. Keegan

    2008-01-01

    Human Resource Management (HRM) in project-oriented organizations is a relatively unexplored topic though it is essential to the success of the organization and its competitive advantage. Project-oriented organizations operate differently from classic business organizations in that they adopt tempor

  6. Human resource management in the project-oriented organization

    NARCIS (Netherlands)

    Turner, J.R.; Huemann, M.; Keegan, A.

    2008-01-01

    Human Resource Management (HRM) in project-oriented organizations is a relatively unexplored topic though it is essential to the success of the organization and its competitive advantage. Project-oriented organizations operate differently from classic business organizations in that they adopt

  7. The Prospects of Membership in International Organizations: The Case of Kosovo

    Directory of Open Access Journals (Sweden)

    Ardian Emini

    2016-12-01

    Full Text Available The purpose of this paper is to analyze the perspective of Kosovo and its membership in international organizations. There are three pillars upon which the analysis of the paper is built. Initially the general question of theoretical frameworks in general the organizations which focus on the elaboration of the very concept of statehood and state-building in general and specifically on Kosovo. The final section deals with a range of behaviors and initiatives of countries in general and the challenges for membership in international organizations. With the aim of contextualizing the subject, the paper focuses on the case of Kosovo state and membership in international organizations with a view to strengthening the international subjectivity and security in the international arena. Finally, the paper concludes that the importance of the accession countries, namely Kosovo's membership in international organizations, and the use of multilateral diplomacy are vital to their safety and welfare.

  8. Human Resource Management in Virtual Organizations. Research in Human Resource Management Series.

    Science.gov (United States)

    Heneman, Robert L., Ed.; Greenberger, David B., Ed.

    This document contains 14 papers on human resources (HR) and human resource management (HRM) in virtual organizations. The following papers are included: "Series Preface" (Rodger Griffeth); "Volume Preface" (Robert L. Heneman, David B. Greenberger); "The Virtual Organization: Definition, Description, and…

  9. Human internal and external exposure to PBDEs - A review of levels and sources

    DEFF Research Database (Denmark)

    Frederiksen, Marie; Vorkamp, Katrin; Thomsen, Marianne

    2009-01-01

    ingest more dust than adults. Infants are also exposed to PBDEs via breast milk. Internal human exposure has generally been found to be one order of magnitude larger in North America than in Europe and Asia. These differences cannot solely be explained by the dietary intake as meat products are the only......This paper reviews the existing literature on human exposure to polybrominated diphenyl ethers (PBDEs), with particular focus on external exposure routes (e.g. dust, diet, and air) and the resulting internal exposure to PBDEs (e.g. breast milk and blood). Being lipophilic and persistent organic...... compounds, PBDEs accumulate in lipid-rich tissues. Consequently, food items like fish from high trophic levels or lipid-rich oils have been found to contain relatively high concentrations of PBDEs, thus presenting an important exposure pathway to humans. The presence of PBDEs in various products of everyday...

  10. The third international workshop of human chromosome 5. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    The Third International Workshop on Human Chromosome 5 was held in Laguna Beach, California, March 5-8, 1994. The pace at which new mapping information has been published in the last year make almost any report outdated before publication. Much of the information in this report and the most recent data from the Human chromosome 5 Genome Center at U.C. Irvine on the physical map of chromosome 5 are accessible via a WWW server. For most loci referred to in this report that can be detected by Polymerase Chain Reaction, the sequences of the oligonucleotide primers are available and some primer sequences are provided in this report.

  11. Similarity or dissimilarity in the relations between human service organizations.

    Science.gov (United States)

    Bruynooghe, Kevin; Verhaeghe, Mieke; Bracke, Piet

    2008-01-01

    Exchange theory and homophily theory give rise to counteracting expectations for the interaction between human service organizations. Based on arguments of exchange theory, more interaction is expected between dissimilar organizations having complementary resources. Based on arguments of homophily theory, organizations having similar characteristics are expected to interact more. Interorganizational relations between human service organizations in two regional networks in Flanders are examined in this study. Results indicate that human service organizations tend to cooperate more with similar organizations as several homophily effects but not one effect of dissimilarity were found to be significant. The results of this study contribute to the understanding of interorganizational networks of human service organizations and have implications for the development of integrated care.

  12. International human rights law aspects of forced migrations, evictions and displacement: current issues and challenges

    OpenAIRE

    Scholten, Andrew

    2016-01-01

    The aim of this paper is an analysis of the categories of evictions, forced migrations and internal displacement in the context of international human rights law. Forced migrations and selected categories of internal displacement are important issues of international human rights law and international humanitarian law for more than forty years. The UDHR, adopted in 1948, does not contain any provisions related to forced human mobility and internal displacement. Despite this fact ...

  13. Strategic human resource management: insights from the international hotel industry

    OpenAIRE

    Gannon, Judie; Roper, Angela; Liz, Doherty

    2015-01-01

    In the strategic human resource management (SHRM) field three approaches have dominated, namely, the universal or best-practice, best-fit or contingency and resource-based view (RBV). This study investigates evidence for the simultaneous or mixed adoption of these approaches by eight case study firms in the international hotel industry. Findings suggest there is considerable evidence of the combined use of the first two approaches but that the SHRM RBV approach was difficult to achieve by all...

  14. Endocrine activity of persistent organic pollutants accumulated in human silicone implants — Dosing in vitro assays by partitioning from silicone

    DEFF Research Database (Denmark)

    Gilbert, Dorothea; Mayer, Philipp; Pedersen, Mikael

    2015-01-01

    Persistent organic pollutants (POPs) accumulated in human tissues may pose a risk for human health by interfering with the endocrine system. This study establishes a new link between actual human internal POP levels and the endocrine active dose in vitro, applying partitioning-controlled dosing...

  15. Euthanasia and international human rights law: prolegomena for an international debate.

    Science.gov (United States)

    Van den Akker, B; Janssens, R M; Ten Have, H A

    1997-10-01

    In this paper we examine in what respects international human rights law can provide a basis for the establishment of an international debate on euthanasia. Such a debate seems imperative, as in many countries euthanasia is considered taboo in the context of medical practice, yet at the same time, supposedly, decisions are taken to intentionally shorten patients' lives. In the Netherlands, the act of euthanasia will not lead to the prosecution of the physician involved if the physician has complied with certain procedures. The Dutch debate centres on procedures marginalizing important moral aspects of euthanasia. An international debate, addressing the fundamental morality of euthanasia and of other medical decisions involving the end of life, will eventually enhance medical practice in the Netherlands as well as in other countries.

  16. 76 FR 60574 - Self-Regulatory Organizations; International Securities Exchange, Incorporated; Notice of...

    Science.gov (United States)

    2011-09-29

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, Incorporated; Notice of Proposed... given that on September 21, 2011, the International Securities Exchange, LLC (the ``Exchange'' or the.... 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of...

  17. 78 FR 65400 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2013-10-31

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and... thereunder,\\2\\ notice is hereby given that on October 17, 2013, the International Securities Exchange, LLC... the self-regulatory organization. The Commission is publishing this notice to solicit comments on...

  18. 77 FR 40121 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2012-07-06

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...\\ notice is hereby given that on June 20, 2012, the International Securities Exchange, LLC (the ``Exchange... Organization's Statement of the Terms of Substance of the Proposed Rule Change The ISE proposes to amend...

  19. 76 FR 48187 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by International...

    Science.gov (United States)

    2011-08-08

    ... COMMISSION Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by International... July 25, 2011, the International Securities Exchange, Inc. (``ISE'' or the ``Exchange'') filed with the...). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of Substance of...

  20. 77 FR 3308 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2012-01-23

    ...] Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and Immediate... 19b-4 thereunder,\\2\\ notice is hereby given that, on January 5, 2012, the International Securities... Organization's Statement of the Terms of Substance of the Proposed Rule Change The ISE is proposing to...

  1. Functional Patterns in International Organizations for University Cooperation in Latin America and the Caribbean

    Science.gov (United States)

    Lopez, Daniel A.; Lopez, Daniel C.; Andrade, Lorenzo I.; Lopez, Boris A.

    2011-01-01

    This study analyzes the coverage, organizational patterns, problems and trends of international organizations for university cooperation in Latin America and the Caribbean. More than 30 international organizations for cooperation currently operating in Latin America and the Caribbean were identified. Two groups of institutions with more than 60%…

  2. 75 FR 27029 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2010-05-13

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and... 19b-4 thereunder,\\2\\ notice is hereby given that on April 30, 2010, the International Securities... prepared by the self- regulatory organization. The Commission is publishing this notice to solicit...

  3. 76 FR 64136 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2011-10-17

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and... International Securities Exchange, LLC (the ``Exchange'' or ``ISE'') filed with the Securities and Exchange... the self-regulatory organization. The Commission is publishing this notice to solicit comments on...

  4. 78 FR 48742 - Self-Regulatory Organizations; Miami International Securities Exchange LLC; Notice of Filing and...

    Science.gov (United States)

    2013-08-09

    ... COMMISSION Self-Regulatory Organizations; Miami International Securities Exchange LLC; Notice of Filing and... thereunder,\\2\\ notice is hereby given that on July 23, 2013, Miami International Securities Exchange LLC...- regulatory organization. The Commission is publishing this notice to solicit comments on the proposed...

  5. 78 FR 78435 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2013-12-26

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and... thereunder,\\2\\ notice is hereby given that on December 18, 2013, the International Securities Exchange, LLC.... \\1\\ 15 U.S.C. 78s(b)(1) \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of...

  6. 76 FR 77275 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing of...

    Science.gov (United States)

    2011-12-12

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing of... on November 29, 2011, the International Securities Exchange, LLC (the ``Exchange'' or the ``ISE...(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of...

  7. 78 FR 11921 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing of...

    Science.gov (United States)

    2013-02-20

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing of... 19b-4 thereunder,\\2\\ notice is hereby given that on February 6, 2013, the International Securities... self-regulatory organization. The Commission is publishing this notice to solicit comments on...

  8. 31 CFR 538.531 - Official activities of the United States Government and international organizations.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Official activities of the United States Government and international organizations. 538.531 Section 538.531 Money and Finance: Treasury....531 Official activities of the United States Government and international organizations. (a)...

  9. 76 FR 41850 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing of...

    Science.gov (United States)

    2011-07-15

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing of... on July 1, 2011, the International Securities Exchange, LLC (the ``Exchange'' or the ``ISE'') filed...). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of Substance of...

  10. 76 FR 31385 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing of...

    Science.gov (United States)

    2011-05-31

    ... COMMISSION [Release No. 34-64538; File No. SR-ISE-2011-30) Self-Regulatory Organizations; International... thereunder,\\2\\ notice is hereby given that on May 23, 2011, the International Securities Exchange, LLC (the.... \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of...

  11. 77 FR 17102 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2012-03-23

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...\\ notice is hereby given that on March 7, 2012, the International Securities Exchange, LLC (the ``Exchange.... \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of...

  12. 77 FR 35729 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2012-06-14

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and... hereby given that on June 1, 2012, the International Securities Exchange, LLC (the ``Exchange'' or the.... 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of...

  13. 75 FR 79058 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2010-12-17

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...\\ notice is hereby given that on November 30, 2010, the International Securities Exchange, LLC (the...-regulatory organization. The Commission is publishing this notice to ] solicit comments on the proposed...

  14. 48 CFR 1845.405 - Contracts with foreign governments or international organizations.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contracts with foreign governments or international organizations. 1845.405 Section 1845.405 Federal Acquisition Regulations System... Rental of Government Property 1845.405 Contracts with foreign governments or international organizations....

  15. 78 FR 75439 - Self-Regulatory Organizations; Miami International Securities Exchange LLC; Notice of Filing and...

    Science.gov (United States)

    2013-12-11

    ... COMMISSION Self-Regulatory Organizations; Miami International Securities Exchange LLC; Notice of Filing and... is hereby given that on November 26, 2013, Miami International Securities Exchange LLC (``MIAX'' or.... 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of...

  16. FREEDOM OF SPEECH IN INDONESIAN PRESS: INTERNATIONAL HUMAN RIGHTS PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Clara Staples

    2016-06-01

    Full Text Available This paper will firstly examine the international framework of human rights law and its guidelines for safeguarding the right to freedom of speech in the press. Secondly, it will describe the constitutional and other legal rights protecting freedom of speech in Indonesia and assess their compatibility with the right to freedom of speech under the international human rights law framework. Thirdly it will consider the impact of Indonesia’s constitutional law and criminal and civil law, including sedition and defamation laws, and finally media ownership, on the interpretation and scope of the right to freedom of speech in the press. Consideration of these laws will be integrated with a discussion of judicial processes. This discussion will be used to determine how and in what circumstances the constitutional right to freedom of speech in the press may be facilitated or enabled, or on the other hand, limited, overridden or curtailed in Indonesia. Conclusions will then be drawn regarding the strengths and weaknesses of Indonesian laws in safeguarding the right to freedom of speech in the press and the democratic implications from an international human rights perspective. This inquiry will be restricted to Indonesian laws in existence during the post-New Order period of 1998 to the present, and to the information and analysis provided by English-language sources.

  17. Human rights, cultural pluralism, and international health research.

    Science.gov (United States)

    Marshall, Patricia A

    2005-01-01

    In the field of bioethics, scholars have begun to consider carefully the impact of structural issues on global population health, including socioeconomic and political factors influencing the disproportionate burden of disease throughout the world. Human rights and social justice are key considerations for both population health and biomedical research. In this paper, I will briefly explore approaches to human rights in bioethics and review guidelines for ethical conduct in international health research, focusing specifically on health research conducted in resource-poor settings. I will demonstrate the potential for addressing human rights considerations in international health research with special attention to the importance of collaborative partnerships, capacity building, and respect for cultural traditions. Strengthening professional knowledge about international research ethics increases awareness of ethical concerns associated with study design and informed consent among researchers working in resource-poor settings. But this is not enough. Technological and financial resources are also necessary to build capacity for local communities to ensure that research results are integrated into existing health systems. Problematic issues surrounding the application of ethical guidelines in resource-poor settings are embedded in social history, cultural context, and the global political economy. Resolving the moral complexities requires a commitment to engaged dialogue and action among investigators, funding agencies, policy makers, governmental institutions, and private industry.

  18. The necessity of strengthening the cooperation between tissue banks and organ transplant organizations at national, regional, and international levels.

    Science.gov (United States)

    Morales Pedraza, Jorge

    2013-12-01

    The donation of tissues and organs increases significantly when tissue banks and organ transplant organizations work together in the procurement of organs and tissues at donor sources (hospitals, coroners system, organ procurement agencies, and funeral homes, among others). To achieve this important goal, national competent health authorities should considered the establishment of a mechanism that promote the widest possible cooperation between tissue banks and organ transplant organizations with hospitals, research medical institutions, universities, and other medical institutions and facilities. One of the issues that can facilitate this cooperation is the establishment of a coding and traceability system that could identify all tissues and organs used in transplant activities carried out in any country. The promotion of national, regional, and international cooperation between tissue banks and organ transplant organizations would enable the sharing of relevant information that could be important for medical practice and scientific studies carried out by many countries, particularly for those countries with a weak health care system.

  19. Internal marketing within a health care organization: developing an implementation plan.

    Science.gov (United States)

    Hallums, A

    1994-05-01

    This paper discusses how the concept of internal marketing can be applied within a health care organization. In order to achieve a market orientation an organization must identify the needs and wants of its customers and how these may change in the future. In order to achieve this, internal marketing is a necessary step to the implementation of the organizations marketing strategy. An outline plan for the introduction of an internal marketing programme within an acute hospital trust is proposed. The plan identifies those individuals and departments who should be involved in the planning and implementation of the programme. The benefits of internal marketing to the Trust are also considered.

  20. {sup 131}I-CRTX internal dosimetry: animal model and human extrapolation

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Henrique Martins de; Ferreira, Andrea Vidal; Soares, Marcella Araugio; Silveira, Marina Bicalho; Santos, Raquel Gouvea dos [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN-CNEN-MG), Belo Horizonte, MG (Brazil)], e-mail: hma@cdtn.br

    2009-07-01

    Snake venoms molecules have been shown to play a role not only in the survival and proliferation of tumor cells but also in the processes of tumor cell adhesion, migration and angiogenesis. {sup 125}I-Crtx, a radiolabeled version of a peptide derived from Crotalus durissus terrificus snake venom, specifically binds to tumor and triggers apoptotic signalling. At the present work, {sup 125}I-Crtx biokinetic data (evaluated in mice bearing Erlich tumor) were treated by MIRD formalism to perform Internal Dosimetry studies. Doses in several organs of mice were determinate, as well as in implanted tumor, for {sup 131}I-Crtx. Doses results obtained for animal model were extrapolated to humans assuming a similar concentration ratio among various tissues between mouse and human. In the extrapolation, it was used human organ masses from Cristy/Eckerman phantom. Both penetrating and non-penetrating radiation from {sup 131}I in the tissue were considered in dose calculations. (author)

  1. {sup 131}I-SPGP internal dosimetry: animal model and human extrapolation

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Henrique Martins de; Ferreira, Andrea Vidal; Soprani, Juliana; Santos, Raquel Gouvea dos [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN-CNEN-MG), Belo Horizonte, MG (Brazil)], e-mail: hma@cdtn.br; Figueiredo, Suely Gomes de [Universidade Federal do Espirito Santo, (UFES), Vitoria, ES (Brazil). Dept. de Ciencias Fisiologicas. Lab. de Quimica de Proteinas

    2009-07-01

    Scorpaena plumieri is commonly called moreia-ati or manganga and is the most venomous and one of the most abundant fish species of the Brazilian coast. Soprani 2006, demonstrated that SPGP - an isolated protein from S. plumieri fish- possess high antitumoral activity against malignant tumours and can be a source of template molecules for the development (design) of antitumoral drugs. In the present work, Soprani's {sup 125}ISPGP biokinetic data were treated by MIRD formalism to perform Internal Dosimetry studies. Absorbed doses due to the {sup 131}I-SPGP uptake were determinate in several organs of mice, as well as in the implanted tumor. Doses obtained for animal model were extrapolated to humans assuming a similar ratio for various mouse and human tissues. For the extrapolation, it was used human organ masses from Cristy/Eckerman phantom. Both penetrating and non-penetrating radiation from {sup 131}I were considered. (author)

  2. The Organization of Islamic Cooperation in contemporary international society

    Directory of Open Access Journals (Sweden)

    Víctor Luis Gutiérrez Castillo

    2014-06-01

    Full Text Available The Organisation of Islamic Cooperation (OIC is an international organisation consisting of 57 member States of Muslim confession, also Palestina. This organisation is "the collective voice of the Muslim world" and works to "safeguard and protect the interests of the Muslim world in the spirit of promoting international peace and harmony". In 28 June 2011 during the 38th Council of Foreign Ministers meeting (CFM in Astana (Kazakhstan the organisation changed its name from Organisation of the Islamic Conference to its current name.The OIC also changed its logo at this time.The Organisation of Islamic Cooperation (OIC has a permanent delegation of the United Nations and it’s the second largest international organisation outside the United Nations. In recent years it has been increasing its importance in the international society and it has played an important role in regional conflicts

  3. EPA's Role in the International Maritime Organization (IMO)

    Science.gov (United States)

    IMO promotes cooperation in regulation of shipping in international trade and encourages the adoption of the highest practicable standards concerning maritime safety, efficiency of navigation, and prevention and control of marine pollution from ships.

  4. 76 FR 27677 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing of...

    Science.gov (United States)

    2011-05-12

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing of Proposed Rule Change by International Securities Exchange to Amend ISE Rule 2102 May 6, 2011. Pursuant to...\\ notice is hereby given that on May 5, 2011, the International Securities Exchange, LLC (the...

  5. 76 FR 72367 - Income of Foreign Governments and International Organizations; Correction

    Science.gov (United States)

    2011-11-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Parts 1 and 602 RIN 1545-BG08 Income of Foreign Governments and International Organizations; Correction AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Correction...

  6. 8 CFR 316.20 - American institutions of research, public international organizations, and designations under the...

    Science.gov (United States)

    2010-01-01

    ... international organizations, and designations under the International Immunities Act. 316.20 Section 316.20... under the International Immunities Act. (a) American institutions of research. The following-listed... University of Beirut (Near East College Associations). Arctic Institute of North America, Inc. Armour...

  7. A theoretical model to address organizational human conflict and disruptive behavior in health care organizations.

    Science.gov (United States)

    Piper, Llewellyn E

    2006-01-01

    This article proposes a theoretical model for leaders to use to address organizational human conflict and disruptive behavior in health care organizations. Leadership is needed to improve interpersonal relationships within the workforce. A workforce with a culture of internal conflict will be unable to achieve its full potential to delivery quality patient care.

  8. Self-organized internal architectures of chiral micro-particles

    OpenAIRE

    2014-01-01

    The internal architecture of polymeric self-assembled chiral micro-particles is studied by exploring the effect of the chirality, of the particle sizes, and of the interface/surface properties in the ordering of the helicoidal planes. The experimental investigations, performed by means of different microscopy techniques, show that the polymeric beads, resulting from light induced polymerization of cholesteric liquid crystal droplets, preserve both the spherical shape and the internal self-org...

  9. Globalizing Lifelong Learning - International Organizations' Strategies of Lifelong Learning

    OpenAIRE

    Zapp, Mike

    2012-01-01

    While the 1970s still knew 'permanent education' (Council of Europe), 'recurrent education' (OECD) and 'lifelong education' (UNESCO), over the past 20 years, 'lifelong learning' has become the single buzz word and catch-all term for reform in above all (pre-) primary, higher and adult education in both national and international education policy making. Both highly industrialized and less industrialized countries embrace the term, in many cases motivated by international and supra...

  10. Documentation: International Legal Human Rights Framework -- Human Rights and the Institutionalisation of ASEAN: An Ambiguous Relationship

    Directory of Open Access Journals (Sweden)

    Theodor Rathgeber

    2014-01-01

    Full Text Available While the ASEAN Charter of 2007 heralded an era of improved democracy, human rights protection and good governance in accordance with the rule of law, the reality on the ground tells a different story. While all of the trappings of a human rights mechanism are in place, the normative and protective capacity of the regime is ambiguous at best. The adoption of core international human rights treaties by ASEAN member states presents an ambiguous picture, one which reveals significant variations between the ten countries. The purported institutionalisation of international human rights standards since 2007 in the region via the creation of an ASEAN human rights mechanism in that year is betrayed by the poor condition of actual protection of human rights at the national and regional level. The article analyses the situation on the ground in light of the normative obligations and aspirations of the states.

  11. Reverse Engineering Human Pathophysiology with Organs-on-Chips.

    Science.gov (United States)

    Ingber, Donald E

    2016-03-10

    While studies of cultured cells have led to new insights into biological control, greater understanding of human pathophysiology requires the development of experimental systems that permit analysis of intercellular communications and tissue-tissue interactions in a more relevant organ context. Human organs-on-chips offer a potentially powerful new approach to confront this long-standing problem.

  12. The Discourse on Human Rights and the International Regime of Human Rights

    Directory of Open Access Journals (Sweden)

    Eyassu Gayim

    2016-11-01

    Full Text Available The international regime of human rights governs the kinds of freedoms, liberties, benefits, autonomy and protection which human beings are entitled to, what kind of obligations we have in this connection and what the roles of states are in recognizing and protecting these rights. Yet, the sources, foundation and justifications for these rights and who we are by nature to deserve some rights has been contentious over the centuries, not least because we live in social context, which requires balancing rights by meeting the broader community interests: political order, stability, and satisfying the general welfare. This paper re-visits the major contentious positions in the discourse on human rights for purposes of explaining how the international community has navigated when shaping the contours of the international regime of human rights. Has this regime endorsed, rejected or avoided some of these positions? Does it follow a clear political ideology?

  13. The Council for International Organizations and Medical Sciences (CIOMS) guidelines on ethics of clinical trials.

    Science.gov (United States)

    Macrae, Duncan J

    2007-05-01

    Numerous bodies from many countries, including governments, government regulatory departments, research organizations, medical professional bodies, and health care providers, have issued guidance or legislation on the ethical conduct of clinical trials. It is possible to trace the development of current guidelines back to the post-World War II Nuremburg war crimes trials, more specifically the "Doctors' Trial." From that trial emerged the Nuremburg Code, which set out basic principles to be observed when conducting research involving human subjects and which subsequently formed the basis for comprehensive international guidelines on medical research, such as the Declaration of Helsinki. Most recently, the Council for International Organizations and Medical Sciences (CIOMS) produced detailed guidelines (originally published in 1993 and updated in 2002) on the implementation of the principles outlined in the Declaration of Helsinki. The CIOMS guidelines set in an appropriate context the challenges of present-day clinical research, by addressing complex issues including HIV/AIDS research, availability of study treatments after a study ends, women as research subjects, safeguarding confidentiality, compensation for adverse events, as well guidelines on consent.

  14. Fourth international workshop on human chromosome 5. Final progress report

    Energy Technology Data Exchange (ETDEWEB)

    McPherson, J.D.

    1996-12-31

    The Fourth International Workshop on Human Chromosome 5 was held in Manchester, UK on November 9--10, 1996 and was hosted by the University of Manchester. The major goals of the workshop were: (1) to collate the various genetic, cytogenetic and physical maps of human chromosome 5; (2) to integrate these maps and identify/correct discrepancies between them wherever possible; (3) to catalogue the sequence-ready contigs of the chromosome; (4) to co-ordinate the various sequencing efforts to avoid future duplication; (5) to establish the first (to the author`s knowledge) web site for the human chromosome 5 community which contains the above information in a readily accessible form.

  15. PERFORMANCE OF HUMAN RESOURCE MANAGEMENT IN AN INTERNATIONALLY OPERATING COMPANY

    Directory of Open Access Journals (Sweden)

    Ladislav Mura

    2012-02-01

    Full Text Available In our days, society is greatly influenced and altered by the process of internationalization andglobalization. Globalization refers to a whole set of changes, not to one single dimensional change.The process of internationalization puts a special and high importance on the work of humanresources managers. In order to remain successful and competitive in the international businessenvironment, companies have to pay close attention to cultural factors. These may considerablydiffer among workers in multinational companies. We are taking a careful look at human resourcemanagement in this new age, and especially at the impact of globalization and internationalization.Our case study is built on the company MOL, specifically on some of the activities it develops in thefield of human resource management: training programmes, personnel motivation, careerdevelopment. We highlight some of the critical aspects of human resources management at MOL,and see what lessons are being learned and what conclusions we can draw.

  16. Growing human organs in pigs-A dream or reality?

    Science.gov (United States)

    Nagashima, Hiroshi; Matsunari, Hitomi

    2016-07-01

    Organ transplantation has been the last line of therapy for saving patients experiencing end-stage organ failure. However, the success of organ transplantation is critically dependent on the availability of donor organs. There are high expectations for research on organ regeneration as a solution to the donor shortage issue faced by transplantation medicine. Thus, generation of human organs from pluripotent stem cells is now one of the ultimate goals of regenerative medicine. In recent years, several approaches to using pluripotent stem cells to generate organs of complex structure and function have been developed. Reproductive biology plays an indispensable role in the development of innovative organ regeneration researches. In this review, we discuss the potential of the animal biotechnology aiming at making human organs using pigs as a platform. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  17. Human Rights Education in the Perspective of International Human Rights Law

    Institute of Scientific and Technical Information of China (English)

    卓泽渊

    2007-01-01

    @@ In a statement issued on the 2004 World Human Rights Day, Ms.Louse Arbour, United Nations High Commissioner for Human Rights,described human rights education as a strategy tor attainment of "human rights for all," as a basic means for developing a universal culture of human rights, as an instrument for promoting equality and involvement of the people in decision-making under democratic mechanisms, and as an investment to prevent infringements upon human rights and to ward off conflicts of violence. It should be noted that so much importance attached by UN human rights organ to human rights education epitomizes the empowering characters of human rights education and the functions it performs in the global human rights system.

  18. Radiology trainer. Torso, internal organs and vessels. 2. ed.; Radiologie-Trainer. Koerperstamm, innere Organe und Gefaesse

    Energy Technology Data Exchange (ETDEWEB)

    Staebler, Axel [Orthopaedische Klinik Harlaching, Muenchen (Germany). Radiologische Praxis; Erlt-Wagner, Birgit (eds.) [Klinikum der Universitaet Muenchen (Germany). Inst. fuer Klinische Radiologie

    2013-11-01

    The radiology training textbook is based on case studies of the clinical experience, including radiological imaging and differential diagnostic discussion. The scope of this volume covers the torso, internal organs and vessels. The following issues are discussed: lungs, pleura, mediastinum; heart and vascular system; upper abdomen organs; gastrointestinal tract; urogenital system.

  19. Through Internal Control System, Jatirogo Organic Coconut Sugar Farmers Gained Access to the Export Market

    OpenAIRE

    Setyowati, Theresia Eko

    2014-01-01

    By founding Jatirogo organic coconut sugar ICS, 1,554 farmer members now have stronger bargaining power in marketing organic coconut sugar. Jatirogo organic coconut sugar ICS has succeeded to export its organic gula semut. By obtaining international certifications (EU Regulation, NOP-USDA, and JAS), KSU Jatirogo sends organic gula semut to various countries, such as the United States, Australia, and European and Asian countries, by collaborating with KSU Jatirogo and exporting companies. ...

  20. International regulations on the organization of shift work.

    Science.gov (United States)

    Kogi, K

    1998-01-01

    Changes since the early 1990s in international regulations on night and shift work were reviewed, including changes in complex shift systems, greater flexibility, increased female participation in night work and attention to health effects. Recent international regulations have focused on (i) a broadened scope of regulatory measures treating both genders equally, (ii) multifaceted protection, and (iii) consultation weighing many aspects of job design. The application of these international regulations depends on national laws and practice, with possible derogations. It calls for local support measures, including (i) guidelines for enterprise-level consultations on shift schedules, (ii) promotion of health and safety measures, and (iii) participatory strategies for locally adjusted shiftwork arrangements and social support.

  1. Motivation and policies of human resources management in the organization

    Directory of Open Access Journals (Sweden)

    Jovanović Goca

    2017-01-01

    Full Text Available Organizations today operate in an uncertain environment, accompanied by constant change and technological innovation. The greatest impact on performance as the key feature of human resources business. Motivation and employee satisfaction becoming the basis of a modern organization. Motivated employees today represent a strategic resource which confer a competitive advantage of the organization.

  2. World health organization perspective on implementation of International Health Regulations.

    Science.gov (United States)

    Hardiman, Maxwell Charles

    2012-07-01

    In 2005, the International Health Regulations were adopted at the 58th World Health Assembly; in June 2007, they were entered into force for most countries. In 2012, the world is approaching a major 5-year milestone in the global commitment to ensure national capacities to identify, investigate, assess, and respond to public health events. In the past 5 years, existing programs have been boosted and some new activities relating to International Health Regulations provisions have been successfully established. The lessons and experience of the past 5 years need to be drawn upon to provide improved direction for the future.

  3. Internalization of cystatin C in human cell lines.

    Science.gov (United States)

    Ekström, Ulf; Wallin, Hanna; Lorenzo, Julia; Holmqvist, Bo; Abrahamson, Magnus; Avilés, Francesc X

    2008-09-01

    Altered protease activity is considered important for tumour invasion and metastasis, processes in which the cysteine proteases cathepsin B and L are involved. Their natural inhibitor cystatin C is a secreted protein, suggesting that it functions to control extracellular protease activity. Because cystatins added to cell cultures can inhibit polio, herpes simplex and coronavirus replication, which are intracellular processes, the internalization and intracellular regulation of cysteine proteases by cystatin C should be considered. The extension, mechanism and biological importance of this hypothetical process are unknown. We investigated whether internalization of cystatin C occurs in a set of human cell lines. Demonstrated by flow cytometry and confocal microscopy, A-431, MCF-7, MDA-MB-453, MDA-MB-468 and Capan-1 cells internalized fluorophore-conjugated cystatin C when exposed to physiological concentrations (1 microm). During cystatin C incubation, intracellular cystatin C increased after 5 min and accumulated for at least 6 h, reaching four to six times the baseline level. Western blotting showed that the internalized inhibitor was not degraded. It was functionally intact and extracts of cells exposed to cystatin C showed a higher capacity to inhibit papain and cathepsin B than control cells (decrease in enzyme activity of 34% and 37%, respectively). The uptake of labelled cystatin C was inhibited by unlabelled inhibitor, suggesting a specific pathway for the internalization. We conclude that the cysteine protease inhibitor cystatin C is internalized in significant quantities in various cancer cell lines. This is a potentially important physiological phenomenon not previously described for this group of inhibitors.

  4. The Self-Organization of Human Interaction

    DEFF Research Database (Denmark)

    Dale, Rick; Fusaroli, Riccardo; Duran, Nicholas

    2013-01-01

    We describe a “centipede’s dilemma” that faces the sciences of human interaction. Research on human interaction has been involved in extensive theoretical debate, although the vast majority of research tends to focus on a small set of human behaviors, cognitive processes, and interactive contexts....... The problem is that naturalistic human interaction must integrate all of these factors simultaneously, and grander theoretical mitigation cannot come only from focused experimental or computational agendas. We look to dynamical systems theory as a framework for thinking about how these multiple behaviors...

  5. Expanded benefits for humanity from the International Space Station

    Science.gov (United States)

    Rai, Amelia; Robinson, Julie A.; Tate-Brown, Judy; Buckley, Nicole; Zell, Martin; Tasaki, Kazuyuki; Karabadzhak, Georgy; Sorokin, Igor V.; Pignataro, Salvatore

    2016-09-01

    In 2012, the International Space Station (ISS) (Fig. 1) partnership published the updated International Space Station Benefits for Humanity[1], a compilation of stories about the many benefits being realized in the areas of human health, Earth observations and disaster response, and global education. This compilation has recently been revised to include updated statistics on the impacts of the benefits, and new benefits that have developed since the first publication. Two new sections have also been added to the book, economic development of space and innovative technology. This paper will summarize the updates on behalf of the ISS Program Science Forum, made up of senior science representatives across the international partnership. The new section on "Economic Development of Space" highlights case studies from public-private partnerships that are leading to a new economy in low earth orbit (LEO). Businesses provide both transportation to the ISS as well as some research facilities and services. These relationships promote a paradigm shift of government-funded, contractor-provided goods and services to commercially-provided goods purchased by government agencies. Other examples include commercial firms spending research and development dollars to conduct investigations on ISS and commercial service providers selling services directly to ISS users. This section provides examples of ISS as a test bed for new business relationships, and illustrates successful partnerships. The second new section, "Innovative Technology," merges technology demonstration and physical science findings that promise to return Earth benefits through continued research. Robotic refueling concepts for life extensions of costly satellites in geo-synchronous orbit have applications to robotics in industry on Earth. Flame behavior experiments reveal insight into how fuel burns in microgravity leading to the possibility of improving engine efficiency on Earth. Nanostructures and smart fluids are

  6. Expanded Benefits for Humanity from the International Space Station

    Science.gov (United States)

    Rai, Amelia; Robinson, Julie A.; Tate-Brown, Judy; Buckley, Nicole; Zell, Martin; Tasaki, Kazuyuki; Karabadzhak, Georgy; Sorokin, Igor V.; Pignataro, Salvatore

    2016-01-01

    In 2012, the International Space Station (ISS) partnership published the updated International Space Station Benefits for Humanity, 2nd edition, a compilation of stories about the many benefits being realized in the areas of human health, Earth observations and disaster response, and global education. This compilation has recently been revised to include updated statistics on the impacts of the benefits, and new benefits that have developed since the first publication. Two new sections have also been added to the book, economic development of space and innovative technology. This paper will summarize the updates on behalf of the ISS Program Science Forum, made up of senior science representatives across the international partnership. The new section on "Economic Development of Space" highlights case studies from public-private partnerships that are leading to a new economy in low earth orbit (LEO). Businesses provide both transportation to the ISS as well as some research facilities and services. These relationships promote a paradigm shift of government-funded, contractor-provided goods and services to commercially-provided goods purchased by government agencies. Other examples include commercial firms spending research and development dollars to conduct investigations on ISS and commercial service providers selling services directly to ISS users. This section provides examples of ISS as a test bed for new business relationships, and illustrates successful partnerships. The second new section, Innovative Technology, merges technology demonstration and physical science findings that promise to return Earth benefits through continued research. Robotic refueling concepts for life extensions of costly satellites in geo-synchronous orbit have applications to robotics in industry on Earth. Flame behavior experiments reveal insight into how fuel burns in microgravity leading to the possibility of improving engine efficiency on Earth. Nanostructures and smart fluids are

  7. The Inauguration of the International Organization for Cooperation in Evaluation

    Science.gov (United States)

    Mertens, Donna M.

    2005-01-01

    Building an international evaluation community has the potential to strengthen the presence, practice, policies, and theories of evaluation and its contribution to improving the effectiveness of programs, policies, and services by making evaluation more rigorous, visible, and responsive to stakeholders. Following 7 years of work by evaluation…

  8. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are an important astrobiology focus. The ORganics Exposure in Orbit (OREOcube) experiment will investigate, in real time, chemical changes in organic compounds exposed to low Earth orbit radiation conditions on an International Space Stat

  9. 76 FR 46351 - International Civil Aviation Organization's (ICAO) Dangerous Goods Panel; Notice of Public Meeting

    Science.gov (United States)

    2011-08-02

    ... Federal Aviation Administration International Civil Aviation Organization's (ICAO) Dangerous Goods Panel... Organization's (ICAO) Dangerous Goods Panel (DGP) to be held October 11-21, 2011, in Montreal, Quebec, Canada... Aviation Organization's Dangerous Goods Panel (ICAO DGP) Meeting. Proposals that are approved by the...

  10. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are an important astrobiology focus. The ORganics Exposure in Orbit (OREOcube) experiment will investigate, in real time, chemical changes in organic compounds exposed to low Earth orbit radiation conditions on an International Space Stat

  11. Human Resource Development in Changing Organizations.

    Science.gov (United States)

    London, Manuel; Wueste, Richard A.

    This book is intended to help managers and human resource professionals understand organizational change and manage its effects on their own development and that of their subordinates. The following topics are covered in 11 chapters: organizational change, employee motivation, new managerial roles, human performance systems, upward and peer…

  12. Preliminary Measurement of Internal Organs of Congjiang Fragrance Pig and Huanjiang Fragrance Pig

    Institute of Scientific and Technical Information of China (English)

    Shen; Xuelin; Duan; Yongbang; Zhang; Yi; Liu; Peiqiong

    2014-01-01

    Fragrance pig is a famous miniature local breed in China,which is similar to human on the aspects of physical structure,anatomy,nutrition,metabolism and blood biochemical indicators. The internal organs of Congjiang fragrance pig and Huanjiang fragrance pig with different month ages were weighed. The results showed that the proportion of stomach in body weight in Congjiang fragrance pig was higher than that in Min pig,Harbin white and Landrace,and the proportion of large intestine in body weight in Congjiang fragrance pig was also higher than that in ordinary pigs; the weights of heart,liver and kidney in 8- 10 months old Congjiang fragrance pig were similar to that in Chinese adults. This provided reference data for future in-depth development and utilization of fragrance pig.

  13. Ultrastructure of the ganglion on human internal laryngeal nerve.

    Science.gov (United States)

    Ramaswamy, S; Shankar, S K; Manjunath, K Y; Devanathan, P H; Nityaseelan, N

    1994-01-01

    There is now definite evidence for the presence of a macroscopic ganglion on the human internal laryngeal nerve, with the distribution of its post-ganglionic fibres to the glands in the saccule and to the glands at the root of epiglottis in the vicinity of the opening of the saccule. This ganglion could be identified as early as 14 weeks in human foetal larynx, which contains immature neurons. Seven ganglia, dissected from human laryngectomy specimens and resected for carcinoma larynx, were studied by electron microscopy. Ultrastructurally, the neurons and the synaptic terminals had both small, round, luscent vesicles and dense core vesicles. Symmetrical, asymmetrical and electrical synaptic complexes were noted. A few neurons revealed degenerative changes suggestive of axotomy. The location of the ganglion on the internal laryngeal nerve, a branch of nervus vagus, and ultrastructural demonstration of large and small dense core vesicles and small luscent vesicles in the neurons of this ganglion, lead us to believe that the ganglion is parasympathetic in nature.

  14. 8 CFR 319.5 - Public international organizations in which the U.S. participates by treaty or statute.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Public international organizations in which... UNITED STATES CITIZENS § 319.5 Public international organizations in which the U.S. participates by treaty or statute. Organizations designated by the President as international organizations pursuant...

  15. Acompañamiento in Colombia: international human rights protection of IDPs

    Directory of Open Access Journals (Sweden)

    Luis Enrique Eguren

    1999-04-01

    Full Text Available The deployment of international observerscan effectively deter human rights violationsagainst displaced people and those workingwith them. This article discusses the role oforganisations such as Peace BrigadesInternational in providing international humanrights protection.

  16. Mapping internal connectivity through human migration in malaria endemic countries.

    Science.gov (United States)

    Sorichetta, Alessandro; Bird, Tom J; Ruktanonchai, Nick W; Zu Erbach-Schoenberg, Elisabeth; Pezzulo, Carla; Tejedor, Natalia; Waldock, Ian C; Sadler, Jason D; Garcia, Andres J; Sedda, Luigi; Tatem, Andrew J

    2016-08-16

    Human mobility continues to increase in terms of volumes and reach, producing growing global connectivity. This connectivity hampers efforts to eliminate infectious diseases such as malaria through reintroductions of pathogens, and thus accounting for it becomes important in designing global, continental, regional, and national strategies. Recent works have shown that census-derived migration data provides a good proxy for internal connectivity, in terms of relative strengths of movement between administrative units, across temporal scales. To support global malaria eradication strategy efforts, here we describe the construction of an open access archive of estimated internal migration flows in endemic countries built through pooling of census microdata. These connectivity datasets, described here along with the approaches and methods used to create and validate them, are available both through the WorldPop website and the WorldPop Dataverse Repository.

  17. Direct determination of internal radiation dose in human blood

    CERN Document Server

    Tanır, Ayse Güneş

    2014-01-01

    The purpose of this study is to measure the internal radiation dose using a human blood sample. In the literature, there is no process that allows the direct measurement of the internal radiation dose received by a person. The luminescence counts from a blood sample having a laboratory-injected radiation dose and the waste blood of the patient injected with a radiopharmaceutical for diagnostic purposes were both measured. The decay and dose-response curves were plotted for the different doses. The doses received by the different blood aliquots can be determined by interpolating the luminescence counts to the dose-response curve. This study shows that the dose received by a person can be measured directly, simply and retrospectively by using only a very small amount of blood sample. The results will have important ramifications for the medicine and healthcare fields in particular. This will also be very important in cases of suspicion of radiation poisoning, malpractice and so on.

  18. [International cooperation and affirmative action policies: the role of the Pan American Health Organization (PAHO)].

    Science.gov (United States)

    Maio, Marcos Chor; Pires-Alves, Fernando A; Paiva, Carlos Henrique Assunção; Silva Magalhães, Rodrigo Cesar da

    2010-07-01

    The article analyzes the formulation, legitimation, and implementation of a policy with an ethnic/race approach by the Pan American Health Organization (PAHO). The study includes the emergence of the theme within this international organization, the institutional dynamics related to it, and the proposals focused on the Black population in Latin America. These issues are discussed on the basis of interaction between PAHO and a range of intergovernmental agencies and private organizations working in the international health domain. Participation by PAHO in the ethnic/racial theme provides elements for understanding the dual role played by intergovernmental organizations in the new global scenario, as both social actors and arenas. As an important social actor in the international health field, PAHO has produced and disseminated values and guidelines related to the ethnic/racial theme. As an arena, the organization has proven open to various interests, seeking to work harmoniously with them through its internal administration.

  19. Work organization and human resource management

    CERN Document Server

    Davim, J

    2014-01-01

    This book provides support to academics as well as managers, who deal with policies and strategies related to work issues. Effective work practices and good employee relations are a real necessity of nowadays organizations, as they can help to reduce absenteeism, employee turnover, and organizational costs. Instead, they support high levels of commitment, effectiveness, performance as well as productivity. The book focusses on the implications of those changes in productivity and organizations management. It explores the models, tools and processes used by organizations in order to help managers become better prepared to face the challenges and changes in work and, consequently, in the way how to manage todays' organizations.

  20. Design of artificial human joints & organs

    CERN Document Server

    Pal, Subrata

    2013-01-01

    This book covers the design science and methodology of artificial joints and organs.  It presents the mechanical characterization of the hard and soft tissues as well as the viscoelastic properties of the tissue.

  1. The Global Traffic in Human Organs

    OpenAIRE

    2000-01-01

    Inspired by Sweetness and Power, in which Sidney Mintz traces the colonial and mercantilist routes of enslaving tastes and artificial needs, this paper maps a late-20th-century global trade in bodies, body parts, desires, and invented scarcities. Organ transplant takes place today in a transnational space with surgeons, patients, organ donors, recipients, brokers, and intermediariessome with criminal connectionsfollowing new paths of capital and technology in the global economy. The stakes ar...

  2. Release of Human Creativity within an Organization

    Directory of Open Access Journals (Sweden)

    Milan Simončič

    2013-10-01

    Full Text Available Research Question (RQ: What are the conditions for creativity inthe researched organization?Purpose: The purpose of this study was to determine how employees understand the conditions for releasing creative potential in anorganizational unit.Method: The study used a descriptive approach in which the characteristics of creative organizations were defined, the objectivesand policies (expectations of management of the organization were summarized, and a survey among employees was carried out that werestatistically analysed.Results: The results showed to which level conditions for creativityare established, how employees understand organizational policies related to quality, and how employees evaluate the creativity level of management.Organization: The management of organizational units obtain answers related to creativity conditions and influence of leadership. In addition, the research findings will be used to increase individual’s creativity.Society: The research emphasized the importance of the activation process, the promotion and maintenance of creativity within anorganization.Originality: This is the first such study in the researched organization.Limitations/Future Research: The study is based on a questionnaire containing seven statements and was conducted in only one of the organizational units within an organization.

  3. Report on the Second International Workshop on Human Chromosome 9

    Energy Technology Data Exchange (ETDEWEB)

    Kwiatkowski, D.J. [Brigham and Women`s Hospital, Boston, MA (United States); Armour, J. [Univ. of Leicester (England). Dept. of Genetics; Bale, A.E. [Yale Univ., New Haven, CT (United States). Dept. of Genetics] [and others

    1993-12-31

    The Second International Workshop on Human Chromosome 9 was held in Chatham, Massachusetts on April 18--20, 1993. Fifty-three abstracts were received and the data presented on posters. The purpose of the meeting was to bring together all interested investigators working on the map of chromosome 9, many of whom had disease-specific interests. After a brief presentation of interests and highlighted results, the meeting broke up into the following subgroups for production of consensus maps: 9p; 9cen-q32; 9q32 ter. A global mapping group also met. Reports of each of these working groups is presented in the summary.

  4. Human Asset Internalization and Global Sourcing of Services

    DEFF Research Database (Denmark)

    Ørberg Jensen, Peter D.; Petersen, Bent

    In this exploratory study we look at human asset aspects of offshore outsourcing of services that over time become more advanced and strategic potent to the outsourcing firms. As a consequence, the outsourcing firms might want to internalize the operations. We focus on the ways that outsourcing...... firms may transfer key personnel of local service providers to whollyownedsubsidiaries. We argue that a felt need for applying more powerful incentives on key personnel of the service provider ‐ to harness and empower the sourcing operation ‐ may in itself be a motive for, and key driver of...

  5. Human Internal Jugular Valve M-mode Ultrasound Characterization

    OpenAIRE

    Menegatti, Erica; Tessari, Mirko; Gianesini, Sergio; Vannini, Maria Elena; Sisini, Francesco; Zamboni, Paolo

    2013-01-01

    In humans the mechanism governing the internal jugular vein (IJV) valve opening and closure is still unclear. M-mode is used in echo-cardiology for the heart valves assessment. Sometimes it was performed also in deep peripheral veins and in vena cava assessment, but never in the IJV valve. Aim of the present study is to investigate the IJV valves physiology in healthy volunteers, by means of both B and M-mode ultrasound. Eighty-three (83) healthy volunteers (35 Male, 48 Female, 25.7±6.7 y.o.)...

  6. The Articles on the Responsibility of International Organizations: magnifying the fissures in the law of international responsibility

    NARCIS (Netherlands)

    d' Aspremont, J.

    2012-01-01

    It is against the backdrop of the conceptual impairment inherited from the Articles on State Responsibility (hereafter ASR) that this note, rather than zeroing in on what could have been better devised at the micro-level of the Articles on the Responsibility of International Organizations (hereafter

  7. The Articles on the Responsibility of International Organizations: Magnifying the Fissures in the Law of International Responsibility

    NARCIS (Netherlands)

    d' Aspremont, J.

    2012-01-01

    It is against the backdrop of the conceptual impairment inherited from the Articles on State Responsibility (hereafter ASR) that this note, rather than zeroing in on what could have been better devised at the micro-level of the Articles on the Responsibility of International Organizations (hereafter

  8. From Subsidiary to Branch Organization of International Banks

    DEFF Research Database (Denmark)

    Goldberg, Lawrence; Sweeney, Richard J.; Wihlborg, Clas

    2005-01-01

    with the intention to reap economies of scale and scope by providing services in an integrated organization. Nordea has so far operated under a legal structure with subsidiaries in the host countries. When the new branch organization is implemented, EU directives specify that the home country is responsible...... for supervision, regulation as well as deposit insurance. Supervisors in all involved countries are challenged by this prospect and they are negotiating to obtain an acceptable division of responsibilities. We argue that the Nordea case offers an opportunity to implement the EU's vision and to develop...

  9. 49 CFR 604.15 - Registration of qualified human service organizations.

    Science.gov (United States)

    2010-10-01

    ... Human Service Organizations and Duties for Recipients With Respect to Charter Registration Web site § 604.15 Registration of qualified human service organizations. (a) Qualified human service... human service organization resides; (3) Basic financial information regarding the qualified...

  10. Human resources evaluation in a marketing organization

    National Research Council Canada - National Science Library

    Gutić Dragutin; Matković Ivan

    2009-01-01

    This work is first of all part of authors' initiated thinking in which in a certain way they try to promote the idea and need to accept and develop the concept of human resources management by marketing managers...

  11. Calibration and commutability assessment of the 1st International Standard for Diphtheria Antitoxin Human.

    Science.gov (United States)

    Stickings, Paul; Rigsby, Peter; Coombes, Laura; von Hunolstein, Christina; Ralli, Luisa; Pinto, Antonella; Sesardic, Dorothea

    2013-11-01

    The 1st International Standard for Diphtheria Antitoxin Human (coded 10/262) was established by the World Health Organization Expert Committee on Biological Standardization in 2012. This paper describes the production, characterization and calibration of the new standard which is intended for use in the standardization of assays used to measure diphtheria antibody responses in human serum. The new standard was calibrated in terms of the International Standard for Diphtheria Antitoxin Equine in an international collaborative study. A total of 8 participants from 8 different countries performed in vivo and/or in vitro toxin neutralization tests and returned data that was used to assign units to the proposed new standard. The new standard has a diphtheria antitoxin potency of 2 IU/ampoule and is predicted to be stable. A follow up study was performed to assess commutability of the new standard. The follow up study was an existing external quality assessment, modified to include the new standard. Results obtained suggest that the new standard is commutable, showing comparable behaviour to native human serum samples in the majority of the assays compared, and is therefore suitable for use as a reference preparation in assays used to measure the level of anti-diphtheria antibodies in human serum.

  12. The Roles of Internal Communications, Human Resource Management and Marketing Concepts in Determining Holistic Internal Marketing Philosophy

    OpenAIRE

    Sinčić Ćorić, Dubravka; Pološki Vokić, Nina

    2009-01-01

    The paper analyses the triad of internal marketing (IM), internal communications (IC) and human resource management (HRM) parallely, which was not the prior interest of academics (so far only the dyads of those concepts were analyzed). The scopes, overlaps and differences between the three concepts are analyzed. By combining three before mentioned concepts a holistic internal marketing philosophy is described. The main conclusions are that a holistic internal marketing philosophy is grounded ...

  13. International agri-food chains and networks. Management and Organization

    NARCIS (Netherlands)

    Bijman, J.; Omta, S.W.F.; Trienekens, J.H.; Wijnands, J.H.M.; Wubben, E.F.M.

    2006-01-01

    This book brings together a rich collection of papers on management and organization in agri-food chains and networks. Producers, processors, traders and retailers of agricultural and food products operate in an economic and institutional environment that is increasingly dominated by global developm

  14. Creating human organs in chimaera pigs : an ethical source of immunocompatible organs?

    NARCIS (Netherlands)

    Shaw, David; Dondorp, Wybo; Geijsen, Niels; de Wert, Guido

    2015-01-01

    New techniques in regenerative medicine may soon enable the creation of human organs inside animals using induced pluripotent stem cells. This technology has the potential to solve the organ scarcity problem by providing a limitless source of personalised organs for transplantation, but also raises

  15. Creating human organs in chimaera pigs : an ethical source of immunocompatible organs?

    NARCIS (Netherlands)

    Shaw, David; Dondorp, Wybo; Geijsen, Niels; de Wert, Guido

    2014-01-01

    New techniques in regenerative medicine may soon enable the creation of human organs inside animals using induced pluripotent stem cells. This technology has the potential to solve the organ scarcity problem by providing a limitless source of personalised organs for transplantation, but also raises

  16. Bio-terrorism, human security and public health: can international law bring them together in an age of globalization?

    Science.gov (United States)

    Aginam, Obijiofor

    2005-09-01

    Bio-terrorism, the use of a microorganism with the deliberate intent of causing infection, before and since the anthrax attacks in the United States in October 2001, has emerged as a real medical and public health threat. The link between bio-terrorism, human security and public health raises complex questions on the normative trajectories of international law, the mandates of international organizations, and global health governance. In May 2001, the World Health Assembly of the World Health Organization (WHO) passed a resolution entitled "Global Health Security: Epidemic Alert and Response" which inter alia, urged WHO member states to participate actively in the verification and validation of surveillance data and information concerning health emergencies of international concern. This article explores the links between bio-terrorism, human security and public health, and investigates the effectiveness of international legal mechanisms that link them in an age of globalization of public health. The article explores the interaction of WHO's 'soft-law' approaches to global health security, and the 'moribund' negotiations of the verification and monitoring protocol to the Biological Weapons Convention 1972. Can international law link bio-terrorism, public health and human security? Does the WHO collaborate with other international organizations within and outside the United Nations system to develop effective legal and governance approaches to bio-terrorism and global health security? The article concludes that the globalization of public health threats like bio-terrorism requires globalized legal approaches.

  17. Humane Society International's global campaign to end animal testing.

    Science.gov (United States)

    Seidle, Troy

    2013-12-01

    The Research & Toxicology Department of Humane Society International (HSI) operates a multifaceted and science-driven global programme aimed at ending the use of animals in toxicity testing and research. The key strategic objectives include: a) ending cosmetics animal testing worldwide, via the multinational Be Cruelty-Free campaign; b) achieving near-term reductions in animal testing requirements through revision of product sector regulations; and c) advancing humane science by exposing failing animal models of human disease and shifting science funding toward human biology-based research and testing tools fit for the 21st century. HSI was instrumental in ensuring the implementation of the March 2013 European sales ban for newly animal-tested cosmetics, in achieving the June 2013 cosmetics animal testing ban in India as well as major cosmetics regulatory policy shifts in China and South Korea, and in securing precedent-setting reductions in in vivo data requirements for pesticides in the EU through the revision of biocides and plant protection product regulations, among others. HSI is currently working to export these life-saving measures to more than a dozen industrial and emerging economies. 2013 FRAME.

  18. Enterococcus faecalis internalization in human umbilical vein endothelial cells (HUVEC).

    Science.gov (United States)

    Millán, Diana; Chiriboga, Carlos; Patarroyo, Manuel A; Fontanilla, Marta R

    2013-04-01

    Initial Enterococcus faecalis-endothelial cell molecular interactions which lead to enterococci associating in the host endothelial tissue, colonizing it and proliferating there can be assessed using in vitro models. Cultured human umbilical vein endothelial cells (HUVEC) have been used to study other Gram-positive bacteria-cell interactions; however, few studies have been aimed at establishing the relationship of E. faecalis with endothelial cells. The aggregation substance (AS) family of adhesins represents an E. faecalis virulence factor which has been implicated in endocarditis severity and bacterial persistence. The Asc10 protein (a member of this family) promotes bacterium-bacterium aggregation and bacterium-host cell binding. Evaluating Asc10 role in bacterial internalization by cultured enterocytes has shown that this adhesin facilitates E. faecalis endocytosis by HT-29 cells. A few eukaryotic cell structural components, such as cytoskeletal proteins, have been involved in E. faecalis entry into cell-lines; it is thus relevant to determine whether Asc10, as well as microtubules and actin microfilaments, play a role in E. faecalis internalization by cultured endothelial cells. The role of Asc10 and cytoskeleton proteins in E. faecalis ability to enter HUVEC was assessed in the present study, as well as cell apoptosis induction by enterococcal internalization by HUVEC; the data indicated increased cell apoptosis and that cytoskeleton components were partially involved in E. faecalis entry to endothelial cells, thereby suggesting that E. faecalis Asc10 protein would not be a critical factor for bacterial entry to cultured HUVEC.

  19. Human motion perception: Higher-order organization

    Science.gov (United States)

    Kaiser, Mary K.; Proffitt, Dennis R.

    1990-01-01

    An overview is given of higher-order motion perception and organization. It is argued that motion is sufficient to fully specify a number of environmental properties, including: depth order, three-dimensional form, object displacement, and dynamics. A grammar of motion perception is proposed; applications of this work for display design are discussed.

  20. Conservation and human rights: the need for international standards

    Energy Technology Data Exchange (ETDEWEB)

    Oviedo, Gonzalo [International Union for the Conservation of Nature (International organizations without location); Pabon, Luis [The Nature Conservancy (United States); Painter, Michael; Redford, Kent [The Wildlife Conservation Society (United States); Siegele, Linda [Foundation for International Environmental Law and Development (United Kingdom); Springer, Jenny [WWF-US (United States); Thomas, David [Birdlife International (International organizations without location); Painemilla, Kristen Walker [Conservation International (United States); Roe, Dilys

    2010-05-15

    Conservation doesn't happen in a vacuum. In recent years, awareness has grown of the relationship of international conservation practice to indigenous peoples and local communities, and especially the links between conservation and human rights. The impacts protected areas can have on rural communities – such as evictions and lost access to natural resources – are now under particular scrutiny. Concern is meanwhile rising over the human rights implications of some climate change mitigation and adaptation measures. But awareness is also growing of the positive contributions of nature conservation to the rights of people to secure their livelihoods, enjoy healthy and productive environments, and live with dignity. International NGOs can play a central role in supporting and promoting conservation actions that respect the rights of indigenous peoples and local communities, and help sustain their livelihoods. Many conservation organisations have long worked towards this. It is vital that they hold to consistent principles and implement measures that ensure their application, so their action on conservation remains accountable, transparent and sustainable.

  1. International Guidelines on Human Rights and Drug Control

    Science.gov (United States)

    Pol, Luciana

    2017-01-01

    Abstract Discrimination and inequality shape women’s experiences of drug use and in the drug trade and the impact of drug control efforts on them, with disproportionate burdens faced by poor and otherwise marginalized women. In recent years, UN member states and UN drug control and human rights entities have recognized this issue and made commitments to integrate a ‘gender perspective’ into drug control policies, with ‘gender’ limited to those conventionally deemed women. But the concept of gender in international law is broader, rooted in socially constructed and culturally determined norms and expectations around gender roles, sex, and sexuality. Also, drug control policies often fail to meaningfully address the specific needs and circumstances of women (inclusively defined), leaving them at risk of recurrent violations of their rights in the context of drugs. This article explores what it means to ‘mainstream’ this narrower version of gender into drug control efforts, using as examples various women’s experiences as people who use drugs, in the drug trade, and in the criminal justice system. It points to international guidelines on human rights and drug control as an important tool to ensure attention to women’s rights in drug control policy design and implementation. PMID:28630557

  2. Integrating International Engineering Organizations For Successful ISS Operations

    Science.gov (United States)

    Blome, Elizabeth; Duggan, Matt; Patten, L.; Pieterek, Hhtrud

    2006-01-01

    The International Space Station (ISS) is a multinational orbiting space laboratory that is built in cooperation with 16 nations. The design and sustaining engineering expertise is spread worldwide. As the number of Partners with orbiting elements on the ISS grows, the challenge NASA is facing as the ISS integrator is to ensure that engineering expertise and data are accessible in a timely fashion to ensure ongoing operations and mission success. Integrating international engineering teams requires definition and agreement on common processes and responsibilities, joint training and the emergence of a unique engineering team culture. ISS engineers face daunting logistical and political challenges regarding data sharing requirements. To assure systematic information sharing and anomaly resolution of integrated anomalies, the ISS Partners are developing multi-lateral engineering interface procedures. Data sharing and individual responsibility are key aspects of this plan. This paper describes several examples of successful multilateral anomaly resolution. These successes were used to form the framework of the Partner to Partner engineering interface procedures, and this paper describes those currently documented multilateral engineering processes. Furthermore, it addresses the challenges experienced to date, and the forward work expected in establishing a successful working relationship with Partners as their hardware is launched.

  3. The politics of inter-regionalism: Relations between international regional organizations

    NARCIS (Netherlands)

    Vleuten, J.M. van der; Ribeiro Hoffman, A.

    2013-01-01

    As the development of relations between international regional organizations, inter-regionalism denotes a relatively recent phenomenon. Largely due to systemic bipolarity, inter-regional relations remained limited to 'dialogue partnerships' between the European Community (EC) and other regional

  4. World Health Organization/International Confederation of Midwives Collaboration: pathways to healthy nations.

    Science.gov (United States)

    Phumaphi, Joy

    2006-03-01

    In this paper, the collaboration between the World Health Organization (WHO) and the International Confederation of Midwives (ICM) to reduce maternal mortality and morbidity, and baby mortality and morbidity, is explicated.

  5. International Labor Organizations, 1864-1997: The Weight of History and the Challenges of the Present

    Directory of Open Access Journals (Sweden)

    Dimitris Stevis

    2015-08-01

    Full Text Available Deepening neoliberal integration, the end of the Cold War, and the decline or compromise of communist and socialist parties, offer a window of opportunity for international labor politics. Why is it, then, that the comprehensive network of global and regional labor organizations continues to play a marginal role, even though they are clearly conscious of these developments, and have sought to respond to them? The answer to this question has important practical and theoretical implications. My general goal, therefore, is to situate the contemporary predicament of international labor organizations within its historical context. Activists would like to know whether labor organizations are basically sound but need to be reformed or fundamentally unsuitable for a vital international labor politics. Theoretically, international labor organizations provide us with a rich record through which to investigate cross-border relations at the level of society and state-society relations.

  6. The politics of inter-regionalism: Relations between international regional organizations

    NARCIS (Netherlands)

    Vleuten, J.M. van der; Ribeiro Hoffman, A.

    2013-01-01

    As the development of relations between international regional organizations, inter-regionalism denotes a relatively recent phenomenon. Largely due to systemic bipolarity, inter-regional relations remained limited to 'dialogue partnerships' between the European Community (EC) and other regional grou

  7. Staphylococcus saprophyticus ATCC 15305 is internalized into human urinary bladder carcinoma cell line 5637.

    Science.gov (United States)

    Szabados, Florian; Kleine, Britta; Anders, Agnes; Kaase, Martin; Sakinç, Türkân; Schmitz, Inge; Gatermann, Sören

    2008-08-01

    Invasion of bacteria into nonphagocytic host cells is an important pathogenicity factor for escaping the host defence system. Gram-positive organisms, for example Staphylococcus aureus and Listeria monocytogenes, are invasive in nonphagocytic cells, and this mechanism is discussed as an important part of the infection process. Uropathogenic Escherichia coli and Staphylococcus saprophyticus can cause acute and recurrent urinary tract infections as well as bloodstream infections. Staphylococcus saprophyticus shows strong adhesion to human urinary bladder carcinoma and Hep2 cells and expresses the 'Microbial Surface Components Recognizing Adhesive Matrix molecule' (MSCRAMM)-protein SdrI with collagen-binding activity. MSCRAMMs are responsible for adhesion and collagen binding in S. aureus and are discussed as an important pathogenicity factor for invasion. To investigate internalization in S. aureus, several fluorescence activated cell sorting (FACS) assays have been described recently. We used a previously described FACS assay, with slight modifications, in addition to an antibiotic protection assay and transmission electron microscopy to show that S. saprophyticus ATCC 15305 and the wild-type strain 7108 were internalized into the human urinary bladder carcinoma cell line 5637. The discovery of the internalization of S. saprophyticus may be an important step for understanding the pathogenicity of recurrent infections caused by this organism.

  8. HUMAN CAPITAL HETEROGENEITY AND ORGANIZATIONAL PERFORMANCE ANALYSIS: AN EMPIRICAL STUDY ABOUT INTERNATIONAL HOTEL CHAINS IN TURKEY

    Directory of Open Access Journals (Sweden)

    Ali Halici

    2012-01-01

    Full Text Available Today, workforce diversity is not only a legal requirement for organizations, but it is also a must to survive in a highly competitive business environment. The prime motive for this study is to investigate the relationship between workforce diversity and perception of discrimination. The basic hypothesis of the study is that as the workforce diversity increases, the perception of discrimination decreases. In order to test the hypothesis, a survey is carried out international hotel chains in Istanbul. There are 19 international hotel chains in Turkey. In this study research is designed to understand human capital heterogeneity pattern of international chains of hotel industry and how this contribute organizational culture strategically that help to manage organizational performance much more efficiently with cross sectional data. Globalization of markets, changing demographics in the labor market, new business strategies requiring team work and the shift from a manufacturing to a service economy are the prime reasons for human capital heterogeneity (HCH. HCH improves the organizational capabilities in terms of flexibility, creativity, problem solving and competitive advantage. Especially in the service sector, in order to gain competitive advantage, organizations need a diverse workforce for both understanding the diverse needs of customers and answering to these needs in a prompt and proper way.

  9. Organization Context and Human Resource Management in the Small Firm

    NARCIS (Netherlands)

    J.M.P. de Kok (Jan); L.M. Uhlaner (Lorraine)

    2001-01-01

    textabstractThis paper examines the relationship between organization contextual variables and human resource management (HRM) practices in small firms. The proposed model is based on an integration of theoretical perspectives, including the resource-based approach, institutional theory, transaction

  10. [Trends of activities in international organization and authorities in each country regarding risk management of nanomaterials].

    Science.gov (United States)

    Shono, Fumiaki; Kumamoto, Masatoshi; Inoue, Kozo

    2013-01-01

    The Organisation for Economic Co-operation and Development (OECD) estimates that in 2015 the worldwide nanotechnology-related market will reach about US$1 trillion and will create about two million additional jobs. The field began with the general technical industry, including many areas of the pharmaceutical, medical, agricultural, and environmental/energy industries, and recently has expanded to the formulation of nanotechnology. In particular, elements of nanometer-sized research and development (R & D) in the areas of drug delivery systems and nanomedicine are attracting widespread interest. On the other hand, the potential negative effects on human health and the environment of nanomaterials manufactured on the industrial scale have not been investigated in detail. Therefore, although the risks have not been fully clarified, research institutions and international organizations such as the OECD are working in earnest to elucidate them. This paper outlines the status of initiatives in industry and regulatory conditions and trends in individual countries and institutions to determine the safety of nanomaterials from the perspective of international relations.

  11. An International Urogynecological Association (IUGA) / International Continence Society (ICS) Joint Report on the Terminology for Female Pelvic Organ Prolapse (POP).

    Science.gov (United States)

    Haylen, Bernard T; Maher, Christopher F; Barber, Matthew D; Camargo, Sérgio; Dandolu, Vani; Digesu, Alex; Goldman, Howard B; Huser, Martin; Milani, Alfredo L; Moran, Paul A; Schaer, Gabriel N; Withagen, Mariëlla I J

    2016-02-01

    The terminology for female pelvic floor prolapse (POP) should be defined and organized in a clinically-based consensus Report. This Report combines the input of members of two International Organizations, the International Urogynecological Association (IUGA) and the International Continence Society (ICS), assisted at intervals by external referees. Appropriate core clinical categories and a sub-classification were developed to give a coding to definitions. An extensive process of fourteen rounds of internal and external review was involved to exhaustively examine each definition, with decision-making by collective opinion (consensus). A Terminology Report for female POP, encompassing over 230 separate definitions, has been developed. It is clinically-based with the most common diagnoses defined. Clarity and user-friendliness have been key aims to make it interpretable by practitioners and trainees in all the different specialty groups involved in female pelvic floor dysfunction and POP. Female-specific imaging (ultrasound, radiology and MRI) and conservative and surgical managements are major additions and appropriate figures have been included to supplement and clarify the text. Emerging concepts and measurements, in use in the literature and offering further research potential, but requiring further validation, have been included as an appendix. Interval (5-10 year) review is anticipated to keep the document updated and as widely acceptable as possible. A consensus-based Terminology Report for female POP has been produced to aid clinical practice and research. © 2016 Wiley Periodicals, Inc., and The International Urogynecological Association.

  12. Marketing communication practices of public organizations to prevent human trafficking

    OpenAIRE

    T.M. Borysova

    2013-01-01

    The aim of the article. The aim of the article is to analyze marketing communicative measures against human trafficking which were implemented by public organizations in 15 regions of Ukraine in 2011-2012. There are following research objectives: to investigate what kind of campaign or program of preventing the potential victims of human trafficking has been used by Ukrainian public organizations during 2011-2012; to determine whether marketing communicative measures have been implement...

  13. Internal branding : Within a Swedish non-profit organization

    OpenAIRE

    Diep, Lisa; Stedt, Amanda

    2015-01-01

    The aid sector has received a lot of attention the recent years whereas the public has recognized the societal situation in developing countries. As many people has become more generous with their donations, an increasing number of non-profit organizations (NPO) has emerged which has created a competitive environment in the non-profit sector. As a result, many NPOs has started to adapt business-like qualities such as implementing a marketing strategy and building a brand. The purpose of this ...

  14. Internal branding : Within a Swedish non-profit organization

    OpenAIRE

    Diep, Lisa; Stedt, Amanda

    2015-01-01

    The aid sector has receive a lot of attention the recent years whereas the public has recognized the societal situation in developing countries. As many people has become more generous with their donations, an increasing number of non-profit organizations (NPO) has emerged which has created a competitive environment in the non-profit sector. As a result, many NPOs has started to adapt business-like qualities such as implementing a marketing strategy and building a brand. The purpose of this s...

  15. 78 FR 77519 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2013-12-23

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and... thereunder,\\2\\ notice is hereby given that, on December 5, 2013, the International Securities Exchange, LLC... handle enforcement jurisdiction in this manner. See supra note 6. With respect to arbitration...

  16. 78 FR 1901 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2013-01-09

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and... Rule 19b-4 thereunder,\\2\\ notice is hereby given that on December 21, 2012, the International... change references in Supplementary Material .01 from NASD to FINRA. ISE Rule 1800 (Arbitration) is being...

  17. Chinese and Taiwanese International College Students' Participation in Social Organizations: Implications for College Counseling Professionals

    Science.gov (United States)

    Tsai, Pei-Chun; Wong, Y. Joel

    2012-01-01

    This qualitative focus group study explored the meaning of Chinese and Taiwanese international students' lived experiences in social organizations. Participants were 9 Chinese and Taiwanese international college students in a midwestern U.S. university. The analyses uncovered 7 themes: social support, recreation, emotional support, practical…

  18. 77 FR 3295 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2012-01-23

    ...] Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and Immediate...\\ notice is hereby given that, on January 3, 2012, the International Securities Exchange, LLC (the... interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory...

  19. 76 FR 2173 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2011-01-12

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and... thereunder,\\2\\ notice is hereby given that on January 5, 2011, the International Securities Exchange, LLC... interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory...

  20. 76 FR 21416 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2011-04-15

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...\\ notice is hereby given that on April 7, 2011, the International Securities Exchange, LLC (the ``Exchange... described in Items I, II, and III below, which items have been prepared by the self-regulatory...

  1. 77 FR 14847 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2012-03-13

    ... COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...,\\2\\ notice is hereby given that on February 22, 2012, the International Securities Exchange, LLC (the... interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory...

  2. Risk analysis and the law: international law, the World Trade Organization, Codex Alimentarius and national legislation.

    Science.gov (United States)

    Horton, L R

    2001-12-01

    This paper discusses the place of risk analysis in international trade from a US perspective, through looking at the activities of the World Trade Organization and the Codex Alimentarius Commission. After examining what the trade agreements say about risk analysis and how international bodies are advancing and using risk analysis, the paper goes on to assess how risk analysis is used at a national level. Finally, recommendations are made for strengthening international food safety initiatives.

  3. Chapter 3: International non-governmental organizations in the emerging world society: the example of ISPRM.

    Science.gov (United States)

    Reinhardt, Jan D; von Groote, Per M; DeLisa, Joel A; Melvin, John L; Bickenbach, Jerome E; Li, Leonard S W; Stucki, Gerold

    2009-09-01

    Using the International Society of Physical and Rehabilitation Medicine (ISPRM) as a case in point, the paper describes the complex world societal situation within which non-governmental organizations that address health issues have to operate.This paper describes the complex world societal situation within which non-governmental organizations (NGOs), that are addressing health issues have to operate. In particular, as an international organization in official relation with the World Health Organization (WHO), ISPRM is confronted with a variety of responsibilities and a true world health political mandate. The accompanying rights need to be played out in relation to its own internal member organization and external allies. The theory of the world society and the current situation are briefly reviewed. The role of international NGOs within the world health polity, rehabilitation and Physical and Rehabilitation Medicine (PRM) is highlighted, whilst special emphasis is placed on NGOs in official relation with WHO. Functions, dysfunctions and challenges of international NGOs operating in the health sector are discussed. Against this background, key approaches to enhance ISPRM's political role are analysed. These include transparent and accountable development of the organization, the differentiation between internal and external policy relations, the harmonization of organizational structures and procedures, the consequential use of political structures available to influence WHO's agenda, and the identification of other policy players of major relevance to PRM in order to build strategic alliances with external partners and to enhance ISPRM's membership base.

  4. 76 FR 50221 - International Workshop on Alternative Methods for Human and Veterinary Rabies Vaccine Testing...

    Science.gov (United States)

    2011-08-12

    ... HUMAN SERVICES International Workshop on Alternative Methods for Human and Veterinary Rabies Vaccine... ``International Workshop on Alternative Methods for Human and Veterinary Rabies Vaccine Testing: State of the... approaches that may reduce, refine, or replace animal use in human and veterinary rabies vaccine...

  5. Self-organized criticality in human epidemiology

    Science.gov (United States)

    Stollenwerk, Nico

    2005-07-01

    As opposed to most sociological fields, data are available in good quality for human epidemiology, describing the interaction between individuals being susceptible to or infected by a disease. Mathematically, the modelling of such systems is done on the level of stochastic master equations, giving likelihood functions for real live data. We show in a case study of meningococcal disease, that the observed large fluctuations of outbreaks of disease among the human population can be explained by the theory of accidental pathogens, leading the system towards a critical state, characterized by power laws in outbreak distributions. In order to make the extremely difficult parameter estimation close to a critical state with absorbing boundary possible, we investigate new algorithms for simulation of the disease dynamics on the basis of winner takes all strategies, and combine them with previously developed parameter estimation schemes.

  6. Investigation of how to implement successful KPIs for organizations – based on an empirical study at an international organization

    OpenAIRE

    Shen, Jing

    2013-01-01

    In the information age, KPIs (Key Performance Indicators) are commonly used for business performance measurement in organizations; however there’s no single best way about how to implement KPIs, which means that a company can select any arbitrary suitable KPIs. The thesis will do research and investigations based on existing academic theory and a case study in an international logistic company. The research was aiming at helping organizations to develop and implement successful KPIs that are ...

  7. Self-Organization and Human Robots

    Directory of Open Access Journals (Sweden)

    Chris Lucas

    2008-11-01

    Full Text Available Humans are rather funny things, we often tend to imagine that we are so ?special?, so divorced by our supposed ?intelligence? from the influences of the ?natural world? and so unique in our ?abstracting? abilities. We have this persistent delusion, evident since ancient Greek times, that we are ?rational?, that we can behave as ?disinterested observers? of our world, which manifests in AI thought today in a belief that, in a like manner, we can ?design?, God like, from afar, our replacements, those ?super-robots? that will do everything that we can imagine doing, but in much ?better? ways than we can achieve, and yet can avoid doing anything ?nasty?, i.e. can overcome our many human failings - obeying, I suppose, in the process, Asimov?s three ?laws of robotics?. Such human naiveté proves, in fact, to be quite amusing, at least to those of us ?schooled? in AI history. When we look at the aspirations and the expectations of our early ?pioneers?, and compare them to the actual reality of today, then we must, it seems, re-discover the meaning of the word ?humility?. Enthusiasm, good as it may be, needs to be moderated with a touch of ?common sense?, and if our current ways of doing things in our AI world don?t really work as we had hoped, then perhaps it is time to try something different (Lucas, C., 1999?

  8. Informed consent in human subject research: a comparison of current international and Nigerian guidelines.

    Science.gov (United States)

    Fadare, Joseph O; Porteri, Corinna

    2010-03-01

    Informed consent is a basic requirement for the conduct of ethical research involving human subjects. Currently, the Helsinki Declaration of the World Medical Association and the International Ethical Guidelines for Biomedical Research of the Council for International Organizations of Medical Sciences (CIOMS) are widely accepted as international codes regulating human subject research and the informed consent sections of these documents are quite important. Debates on the applicability of these guidelines in different socio-cultural settings are ongoing and many workers have advocated the need for national or regional guidelines. Nigeria, a developing country, has recently adopted its national guideline regulating human subject research: the National Health Research Ethics Committee (NHREC) code. A content analysis of the three guidelines was done to see if the Nigerian guidelines confer any additional protection for research subjects. The concept of a Community Advisory Committee in the Nigerian guideline is a novel one that emphasizes research as a community burden and should promote a form of "research friendship" to foster the welfare of research participants. There is also the need for a regular update of the NHREC code so as to address some issues that were not considered in its current version.

  9. Measurement of human potential in organizations

    Directory of Open Access Journals (Sweden)

    Rosa María Fuchs Ángeles

    2015-09-01

    Full Text Available Companies around the world are concerned about talent management in their organizations. The concern is to retain talented employees and this may not be possible if they are not properly identified. Performance and potential evaluations become then important. Performance evaluations qualify the historical record of the employee, so their measurement is provided. However, measuring the potential performance assesses potential future charges, therefore it is not a simple task. In this paper, characteristics evaluated in potential employees and tools that are commonly used are presented. Also, the case of four companies operating in Peru is shown.

  10. Human-friendly organic integrated circuits

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Sekitani

    2011-09-01

    Full Text Available Many electronic systems such as flat-panel displays, optical detectors, and sensor arrays would benefit greatly from mechanical flexibility. Ultraflexible and foldable electronics demonstrate ultimate flexibility, and are highly portable. A major obstacle toward the development of foldable electronics is the fundamental compromise between operation voltage, transistor performance, and mechanical flexibility. This review describes foldable and conformable integrated circuits based on organic thin-film transistors (TFTs with very high mechanical stability. We review our work on such transistors and integrated circuits, that continue to operate without failure, without detectable degradation during folding of the plastic substrate.

  11. 76 FR 13495 - Extending Provisions of the International Organizations Immunities Act to the Office of the High...

    Science.gov (United States)

    2011-03-11

    ... Provisions of the International Organizations Immunities Act to the Office of the High Representative in... International Organizations Immunities Act (59 Stat. 669, 22 U.S.C. 288), and the Extending Immunities to the..., exemptions, and immunities provided by the International Organizations Act be extended to the Office of...

  12. Persistent organic pollutants alter DNA methylation during human adipocyte differentiation

    NARCIS (Netherlands)

    Dungen, van den Myrthe; Murk, Tinka; Steegenga, Wilma; Gils-Kok, van Dieuwertje

    2016-01-01

    Genome-wide DNA methylation profiling was performed in human mesenchymal stem cells (hMSCs) differentiated into adipocytes (day 10) while being continuously exposed to either one of three different persistent organic pollutants (POPs), namely TCDD, PFOS, and TBT. The Illumina Infinium 450K Human DNA

  13. Protection of Human Beings Trafficked for the Purpose of Organ Removal: Recommendations.

    Science.gov (United States)

    Pascalev, Assya; Van Assche, Kristof; Sándor, Judit; Codreanu, Natalia; Naqvi, Anwar; Gunnarson, Martin; Frunza, Mihaela; Yankov, Jordan

    2016-02-01

    This report presents a comprehensive set of recommendations for protection of human beings who are trafficked for the purpose of organ removal or are targeted for such trafficking. Developed by an interdisciplinary group of international experts under the auspices of the project Trafficking in Human Beings for the Purpose of Organ Removal (also known as the HOTT project), these recommendations are grounded in the view that an individual who parts with an organ for money within an illegal scheme is ipso facto a victim and that the crime of trafficking in human beings for the purpose of organ removal (THBOR) intersects with the crime of trafficking in organs. Consequently, the protection of victims should be a priority for all actors involved in antitrafficking activities: those combating organ-related crimes, such as health organizations and survivor support services, and those combating trafficking in human beings, such as the criminal justice sectors. Taking into account the special characteristics of THBOR, the authors identify 5 key stakeholders in the protection of human beings trafficked for organ removal or targeted for such trafficking: states, law enforcement agencies and judiciary, nongovernmental organizations working in the areas of human rights and antitrafficking, transplant centers and health professionals involved in transplant medicine, and oversight bodies. For each stakeholder, the authors identify key areas of concern and concrete measures to identify and protect the victims of THBOR. The aim of the recommendations is to contribute to the development of a nonlegislative response to THBOR, to promote the exchange of knowledge and best practices in the area of victim protection, and to facilitate the development of a policy-driven action plan for the protection of THBOR victims in the European Union and worldwide.

  14. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    Organic compounds that survive in uncommon space environments are animportant astrobiology focus. The ORganics Exposure in Orbit (OREOcube)experiment will investigate, in real time, chemical changes in organiccompounds exposed to low Earth orbit radiation conditions on anInternational Space Station

  15. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are animportant astrobiology focus. The ORganics Exposure in Orbit (OREOcube)experiment will investigate, in real time, chemical changes in organiccompounds exposed to low Earth orbit radiation conditions on anInternational Space Station

  16. A Quantitative Property-Property Relationship for the Internal Diffusion Coefficients of Organic Compounds in Solid Materials

    DEFF Research Database (Denmark)

    Huang, Lei; Fantke, Peter; Jolliet, Olivier

    2017-01-01

    Indoor releases of organic chemicals encapsulated in solid materials are major contributors to human exposures and are directly related to the internal diffusion coefficient in solid materials. Existing correlations to estimate the diffusion coefficient are only valid for a limited number...... of chemical-material combinations. This paper develops and evaluates a quantitative property-property relationship (QPPR) to predict diffusion coefficients for a wide range of organic chemicals and materials. We first compiled a training dataset of 1103 measured diffusion coefficients for 158 chemicals in 32...... consolidated material types. Following a detailed analysis of the temperature influence, we developed a multiple linear regression model to predict diffusion coefficients as a function of chemical molecular weight (MW), temperature, and material type (adjusted R2 of 0.93). The internal validations showed...

  17. Business-nonprofit partnerships as a driver of internal marketing in nonprofit organizations. Consequences for nonprofit performance and moderators

    Directory of Open Access Journals (Sweden)

    Luis Ignacio Álvarez-González

    2017-04-01

    Full Text Available Nonprofit organizations (NPOs confront competitive pressures derived from complex economic and societal challenges. Their capacity to fulfil their mission increasingly depends on developing successful alliances with key external and internal stakeholders, including cooperative interorganizational relationships. In this context, the aim of this research is to analyze: (1 to which extent business-nonprofit partnerships (BNPPs foster the development of an internal marketing approach by NPOs; (2 the impact of this approach to human resource management on nonprofit performance; and (3 the possible moderating effect of the funding strategy of the nonprofit. This empirical research, based on a survey to a representative sample of Spanish NPOs, shows that cooperative relationships between nonprofit and business organizations are closely associated with a process of knowledge transfer, resulting in improved nonprofit performance; although these positive effects depend on the capacity of NPOs to generate income from commercial sources.

  18. Emotional Contagion and Proto-Organizing in Human Interaction Dynamics

    Directory of Open Access Journals (Sweden)

    James K. Hazy

    2015-06-01

    Full Text Available This paper combines the complexity notions of phase transitions and tipping points with recent advances in cognitive neuroscience to propose a general theory of human proto-organizing. It takes as a premise that a necessary prerequisite for organizing, or proto-organizing, occurs through emotional contagion in subpopulations of human interaction dynamics in complex ecosystems. Emotional contagion is posited to engender emotional understanding and identification with others, a social process that acts as a mechanism that enables (or precludes cooperative responses to opportunities and risks. Propositions are offered and further research is suggested.

  19. Transcriptomics resources of human tissues and organs

    OpenAIRE

    Uhlén, Mathias; Hallström, Björn M; Lindskog, Cecilia; Mardinoglu, Adil; Pontén, Fredrik; Nielsen, Jens

    2016-01-01

    Abstract Quantifying the differential expression of genes in various human organs, tissues, and cell types is vital to understand human physiology and disease. Recently, several large‐scale transcriptomics studies have analyzed the expression of protein‐coding genes across tissues. These datasets provide a framework for defining the molecular constituents of the human body as well as for generating comprehensive lists of proteins expressed across tissues or in a tissue‐restricted manner. Here...

  20. [Surgical research in Germany. Organization, quality and international competitiveness].

    Science.gov (United States)

    Menger, M D; Laschke, M W

    2012-04-01

    Surgical research in Germany is performed within surgical clinics by individual working groups or in surgical research divisions. Additionally, a few independent institutes and departments of surgical research have been established at medical faculties. The number of these institutions, however, is too small. To increase productivity in surgical research, structural changes are necessary, including additional establishment of further institutes and professorships. The quality of clinical research in surgery in Germany is critically discussed. International comparison shows that Germany has a low ranking with respect to the number of clinical studies published in leading surgical journals. However, there has been some improvement in the quality of clinical studies performed in surgical departments during the last 15 years. The establishment of the study center of the German Society of Surgery shows that excellent clinical studies with adequate numbers of patients can also be performed in Germany and can be published in leading journals. Accordingly, there is need to distribute the structures and the competence necessary to perform clinical studies in a standardized manner to all surgical departments involved in clinical research. The experimental surgical research in Germany is not adequately visible, although over the last 10 years the most relevant publications from institutions for surgical research have been placed in journals with a mean impact factor of 8. This may be due to the fact that 85% of these top publications are published in non-surgical journals. The aim for the future must therefore be to increase the impact factor and, thus, the attractiveness of surgical journals. This may be achieved by publishing the highest quality results from experimental surgical research not in non-surgical but in surgical journals.

  1. Politics of Internationalism - Danish Women's Movements Participating in the Building of International Women's Organizations (1888-1919)

    DEFF Research Database (Denmark)

    Fiig, Christina; Nielsen, Jytte

    2016-01-01

    The struggle for universal enfranchisement in Denmark went on for almost 70 years and was part of a broader struggle for democratization. Granting women the vote was controversial and affected fundamental power structures and male privileges in marriage, in the labor market and in politics (Fiig...... & Siim 2008: 61). The context for this political and ideological struggle was primarily local and national; however there are reasons to investigate the international inspiration and activism as a central part of the debate and struggle for enfranchisement. In this article, we move beyond the “national...... container” (Beck XX) of Denmark in the time period of 1888-1915 and analyze both the international inspiration in relation to the women’s organizations and the Danish women’s movements’ important role on the international scene....

  2. Quantifying external and internal collagen organization from Stokes-vector-based second harmonic generation imaging polarimetry

    Science.gov (United States)

    Ávila, Francisco J.; del Barco, Oscar; Bueno, Juan M.

    2017-10-01

    Collagen organization has been analyzed at both external and internal scales by combining Stokes-vector polarimetry and second harmonic generation microscopy. A significant linear relationship between the diattenuation and the external collagen organization was found. The dominant orientation of the collagen fibers was found to run parallel to the axis of diattenuation. Information on the collagen chirality was obtained from the circular dichroism, which showed also a strong dependence with the internal collagen organization. The results show that certain polarimetric parameters might be useful to extract quantitative information and characterize collagen arrangement.

  3. 42 CFR 121.13 - Definition of Human Organ Under section 301 of the National Organ Transplant Act, as amended.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Definition of Human Organ Under section 301 of the..., DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH RESOURCES DEVELOPMENT ORGAN PROCUREMENT AND TRANSPLANTATION NETWORK § 121.13 Definition of Human Organ Under section 301 of the National Organ Transplant Act,...

  4. Drug user organizations in the Nordic countries--local, national, and international dimensions.

    Science.gov (United States)

    Frank, Vibeke Asmussen; Anker, Jørgen; Tammi, Tuukka

    2012-04-01

    The article focuses on drug user organizations that represent and advocate for active "hard drug" users in the Nordic countries. It discusses the opportunities and challenges that these organizations face in their search for legitimacy and political influence. The comparative perspective points at similarities and differences in national contexts that both support and challenges the existence of drug user organizations, including drug policy, social welfare policy, trends in drug use, and organizational conditions. The article also discusses the importance of international network and transnational organizations that support drug user organizations.

  5. Marketing of human organs and tissues is justified and necessary.

    Science.gov (United States)

    Kevorkian, J

    1989-01-01

    The bioethical guidelines now banning commerce in human body parts to be used for transplantation manifest unrealistic and arbitrary inflexibility which perpetuates and worsens the deficit in organ supply. Instead of relying on traditionally revered but now outmoded and even irrelevant bioethical maxims, formulators of the guidelines should have concentrated on a more meaningful situational adaptation to contemporary real-life circumstances. Many unexpectedly relevant and important nuances of concepts such as property, ownership, and altruism must now be taken into account. Hypothetical examples explore the morality of a universal ban by fiat and the associated problems of organ supply and demand, of cost and affordability, and of fair equity. It is difficult to justify purely altruistic organ donation today, when the health care professions and industries are frantically pursuing commercial profits. It is concluded that the ban should be scrapped in favor of a well-organized, open, and legally regulated commercial market for human organs and tissues.

  6. Person-Organization Commitment: Bonds of Internal Consumer in the Context of Non-profit Organizations

    Science.gov (United States)

    Juaneda-Ayensa, Emma; Clavel San Emeterio, Mónica; González-Menorca, Carlos

    2017-01-01

    From an Organizational Behavior perspective, it is important to recognize the links generated between individuals and the organization that encourage a desire for permanence. After more than a half century of research, Organizational Commitment remains one of the open questions in the Psychology of Organizations. It is considered an essential factor for explaining individual behavior in the organization such as satisfaction, turnover intention, or loyalty. In this paper, we analyze different contributions regarding the nature of the bond between the individual and the organization. Taking into account the peculiarities of Non-profit Organizations, we present different interpretation for later validation, comparing results from the Confirmatory Factor Analysis of the four models obtained using exploratory factor analysis, both conducted on a sample of 235 members of Non-profit Organizations. PMID:28775699

  7. Person-Organization Commitment: Bonds of Internal Consumer in the Context of Non-profit Organizations.

    Science.gov (United States)

    Juaneda-Ayensa, Emma; Clavel San Emeterio, Mónica; González-Menorca, Carlos

    2017-01-01

    From an Organizational Behavior perspective, it is important to recognize the links generated between individuals and the organization that encourage a desire for permanence. After more than a half century of research, Organizational Commitment remains one of the open questions in the Psychology of Organizations. It is considered an essential factor for explaining individual behavior in the organization such as satisfaction, turnover intention, or loyalty. In this paper, we analyze different contributions regarding the nature of the bond between the individual and the organization. Taking into account the peculiarities of Non-profit Organizations, we present different interpretation for later validation, comparing results from the Confirmatory Factor Analysis of the four models obtained using exploratory factor analysis, both conducted on a sample of 235 members of Non-profit Organizations.

  8. Human Resource Management in Virtual Organizations. Research in Human Resource Management Series.

    Science.gov (United States)

    Heneman, Robert L., Ed.; Greenberger, David B., Ed.

    This document contains 14 papers on human resources (HR) and human resource management (HRM) in virtual organizations. The following papers are included: "Series Preface" (Rodger Griffeth); "Volume Preface" (Robert L. Heneman, David B. Greenberger); "The Virtual Organization: Definition, Description, and Identification" (David B. Greenberger,…

  9. [The status of human cloning in the international setting].

    Science.gov (United States)

    Rey del Castillo, Javier

    2006-01-01

    The General Assembly of the United Nations submitted a Declaration on Human Cloning in March 2005. The text of such Declaration was the result of a difficult and long process, taking more than three years. Being a Declaration instead of a Resolution, it has not legal capability in inforcing United Nations members to act according to its recommendations. This article begins with an explanation of several terms referred to cloning. Different countries' legislation on cloning is analyzed. Positions of the same countries at the Convention of the United Nations are as well analyzed. Comparing both countries' views shows that national legislation on cloning is independent and orientated by some countries' particular interests and biological and ethical views on these issues. Future developments on human cloning and its applications will be shared among all countries, both the ones currently allowing and supporting "therapeutic" cloning and the ones now banning it. In such case, it would be important to reach agreements on these issues at an international level. The article discusses possible legislative developments and offers some proposals to reach such agreements.

  10. Organization of ventricular fibrillation in the human heart.

    Science.gov (United States)

    Ten Tusscher, Kirsten H W J; Hren, Rok; Panfilov, Alexander V

    2007-06-22

    Sudden cardiac death is a major cause of death in the industrialized world, claiming approximately 300,000 victims annually in the United States alone. In most cases, sudden cardiac death is caused by ventricular fibrillation (VF). Experimental studies in large animal hearts have shown that the uncoordinated contractions during VF are caused by large numbers of chaotically wandering reentrant waves of electrical activity. However, recent clinical data on VF in the human heart seem to suggest that human VF may have a markedly different organization. Here, we use a detailed model of the human ventricles, including a detailed description of cell electrophysiology, ventricular anatomy, and fiber direction anisotropy, to study the organization of human VF. We show that characteristics of our simulated VF are qualitatively similar to the clinical data. Furthermore, we find that human VF is driven by only approximately 10 reentrant sources and thus is much more organized than VF in animal hearts of comparable size, where VF is driven by approximately 50 sources. We investigate the influence of anisotropy ratio, tissue excitability, and restitution properties on the number of reentrant sources driving VF. We find that the number of rotors depends strongest on minimum action potential duration, a property that differs significantly between human and large animal hearts. Based on these findings, we suggest that the simpler spatial organization of human VF relative to VF in large animal hearts may be caused by differences in minimum action potential duration. Both the simpler spatial organization of human VF and its suggested cause may have important implications for treating and preventing this dangerous arrhythmia in humans.

  11. Human Ia-like antigens in non-lymphoid organs.

    Science.gov (United States)

    Koyama, K; Fukunishi, T; Barcos, M; Tanigaki, N; Pressman, D

    1979-01-01

    Human Ia-like antigens in liver and kidney were shown by the immunofluorescence assay to be present mostly in the endothelial-mesenchymal cells of these organs. The parenchymal cells apparently contained no human Ia-like antigens. The antigens in liver and kidney were purified and shown to have the same subunit structure as human Ia-like antigens of cultured B-lymphoid cells. The human Ia-like antigens in non-lymphoid organs, not only in liver and kidney but also in testis, heart, muscle and brain, carried all the xenoantigenic characteristics of human Ia-like antigens expressed on lymphoid cells of B-cell lineage. Images Figure 1 PMID:389786

  12. Using non-human primates to benefit humans: research and organ transplantation.

    Science.gov (United States)

    Shaw, David; Dondorp, Wybo; de Wert, Guido

    2014-11-01

    Emerging biotechnology may soon allow the creation of genetically human organs inside animals, with non-human primates (henceforth simply "primates") and pigs being the best candidate species. This prospect raises the question of whether creating organs in primates in order to then transplant them into humans would be more (or less) acceptable than using them for research. In this paper, we examine the validity of the purported moral distinction between primates and other animals, and analyze the ethical acceptability of using primates to create organs for human use.

  13. Ethical issues of transplanting organs from transgenic animals into human beings.

    Science.gov (United States)

    Behnam Manesh, Shima; Omani Samani, Reza; Behnam Manesh, Shayan

    2014-01-01

    One of the most important applications of transgenic animals for medical purposes is to transplant their organs into human's body, an issue which has caused a lot of ethical and scientific discussions. we can divide the ethical arguments to two comprehensive groups; the first group which is known as deontological critiques (related to the action itself regardless of any results pointing the human or animal) and the second group, called the consequentialist critiques (which are directly pointing the consequences of the action). The latter arguments also can be divided to two subgroups. In the first one which named anthropocentrism, just humankind has inherent value in the moral society, and it studies the problem just from a human-based point of view while in second named, biocentrism all the living organism have this value and it deals specially with the problem from the animal-based viewpoint. In this descriptive-analytic study, ethical issues were retrieved from books, papers, international guidelines, thesis, declarations and instructions, and even some weekly journals using keywords related to transgenic animals, organ, and transplantation. According to the precautionary principle with the strong legal and ethical background, due to lack of accepted scientific certainties about the safety of the procedure, in this phase, transplanting animal's organs into human beings have the potential harm and danger for both human and animals, and application of this procedure is unethical until the safety to human will be proven.

  14. 11 CFR 100.134 - Internal communications by corporations, labor organizations, and membership organizations.

    Science.gov (United States)

    2010-01-01

    ... part, of dealing with employers concerning grievances, labor disputes, wages, rates of pay, hours of... means a person who has a vested beneficial interest in stock, has the power to direct how that stock... administer the organization, pursuant to the organization's articles, bylaws, constitution or other formal...

  15. Human vocal organ: visible-human-male-based three-dimensional visualization

    Science.gov (United States)

    Kim, Jae-woo; Lee, Donghun; Han, Jong H.; Kim, Bohyung; Kim, Dongsung; Kang, Heung Sik

    2002-05-01

    The Visible Human Project planned and promoted by National Library of Medicine (NLM) provides cryosection images of the normal male and female human bodies. The anatomy of human vocal organ is difficult to understand and to imagine due to its complexity. The purpose of this study is to develop the three-dimensionally computerized atlas of the human vocal organ using Visible Human male dataset. A self-developed program with C language and a recent personal computer can show specific organs and structures separately or together, rotate them at three axes, cross-section them transparently at any angles, and zoom them in and out. As a result, our own PC-based program will be a more interactive, more detailed, and more realistic three-dimensional computerized atlas of a human vocal organ including larygopharynx.

  16. Body futures: the case against marketing human organs.

    Science.gov (United States)

    Dougherty, C J

    1987-06-01

    Creation of a market for the buying and selling of human organs for transplantation, even if it did allow supply to match demand, would be a serious mistake. Even if the market were fairly constructed, it might not dramatically increase the supply of transplantable organs, since donations likely would decrease if selling were allowed. Such a market would create a relative disadvantage for the poor, who would feel disproportionately greater pressure to sell their organs than would the wealthy. The possibility of realizing a profit from the organs of the dead could provide an incentive for murder or for doing less than we might to save lives. An organ market, where parts of a person are viewed as commodities, could lead to a general cheapening and coarsening of human relationships. Any organ selling system would create an economic relationship between buyer and seller, rather than a charitable one, raising quality control problems. The economic system, would drive out the volunteer donor system, sapping the altruistic bond that draws people together. Finally, an organ market presents a metaphysical threat in that it demeans our bodies to the status of articles to trade. An alternative to the current voluntary donor system and an organ market is to presume passive consent to organ donation with the right to informed refusal. Unless a record of the decedent's opposition to organ removal exists, the next of kin objects on being informed of the intent to remove organs, or the decedent was a member of a group known to oppose organ removal, we should presume a person's willingness to donate organs after death to save another person's life.

  17. Actomyosin-based Self-organization of cell internalization during C. elegans gastrulation

    Directory of Open Access Journals (Sweden)

    Pohl Christian

    2012-11-01

    Full Text Available Abstract Background Gastrulation is a key transition in embryogenesis; it requires self-organized cellular coordination, which has to be both robust to allow efficient development and plastic to provide adaptability. Despite the conservation of gastrulation as a key event in Metazoan embryogenesis, the morphogenetic mechanisms of self-organization (how global order or coordination can arise from local interactions are poorly understood. Results We report a modular structure of cell internalization in Caenorhabditis elegans gastrulation that reveals mechanisms of self-organization. Cells that internalize during gastrulation show apical contractile flows, which are correlated with centripetal extensions from surrounding cells. These extensions converge to seal over the internalizing cells in the form of rosettes. This process represents a distinct mode of monolayer remodeling, with gradual extrusion of the internalizing cells and simultaneous tissue closure without an actin purse-string. We further report that this self-organizing module can adapt to severe topological alterations, providing evidence of scalability and plasticity of actomyosin-based patterning. Finally, we show that globally, the surface cell layer undergoes coplanar division to thin out and spread over the internalizing mass, which resembles epiboly. Conclusions The combination of coplanar division-based spreading and recurrent local modules for piecemeal internalization constitutes a system-level solution of gradual volume rearrangement under spatial constraint. Our results suggest that the mode of C. elegans gastrulation can be unified with the general notions of monolayer remodeling and with distinct cellular mechanisms of actomyosin-based morphogenesis.

  18. The Effect of Competitive Rivalry on Internal Communication in Private Healthcare Organizations: Evidence from Istanbul, Turkey

    Directory of Open Access Journals (Sweden)

    Gültekin Altuntas

    2014-02-01

    Full Text Available Both competitive rivalry and internal communication play a crucial role for a business to position itself in a favourable manner in order to succeed particularly in a hostile environment. While numerous studies present the importance of competitive rivalry and of communication, even internal communication separately, little is known about the specific linkage of how competitive rivalry affects communication in the literature. Within the framework of internal communication, this study focuses on the notion that competitive rivalry is related to the path and style of communication as well as to the usage of internal communication tools but not to quality of communication. Thus, our research presents the linkage and the interaction between competitive rivalry and internal communication, of which the results indicate that, overall, competitive rivalry has a significant direct positive influence on internal communication dimensions in terms of path, style and quality of communication, as well as usage of communication tools in healthcare organizations.

  19. MEG studies of human vision: Retinotopic organization of V1

    Energy Technology Data Exchange (ETDEWEB)

    Aine, C.; George, J.; Ranken, D.; Best, E.; Tiee, W.; Vigil, V.; Flynn, E.; Wood, C. [Los Alamos National Lab., NM (United States); Supek, S. [Zagreb Univ. (Croatia). Dept. of Physics

    1993-12-31

    A primary goal of noninvasive studies of human vision is to identify and characterize multiple visual areas in the human brain analogous to those identified in studies of nonhuman primates. By combining functional MEG measurements with images of individual anatomy derived from MRI, the authors hope to determine the location and arrangement of multiple visual areas in human cortex and to probe their functional significance. The authors have identified several different visual areas thus far which appear to be topographically organized. This paper focuses on the retinotopic characterization of the primary visual area (V1) in humans.

  20. Transcriptomics resources of human tissues and organs

    DEFF Research Database (Denmark)

    Uhlén, Mathias; Hallström, Björn M.; Lindskog, Cecilia

    2016-01-01

    a framework for defining the molecular constituents of the human body as well as for generating comprehensive lists of proteins expressed across tissues or in a tissue-restricted manner. Here, we review publicly available human transcriptome resources and discuss body-wide data from independent genome......Quantifying the differential expression of genes in various human organs, tissues, and cell types is vital to understand human physiology and disease. Recently, several large-scale transcriptomics studies have analyzed the expression of protein-coding genes across tissues. These datasets provide...

  1. The Pan American Health Organization and international health: a history of training, conceptualization, and collective development.

    Science.gov (United States)

    Auer, Annella; Guerrero Espinel, Juan Eduardo

    2011-08-01

    A constantly changing and increasingly complex global environment requires leaders with special competencies to respond effectively to this scenario. Within this context, the Pan American Health Organization (PAHO) goes beyond traditional leadership training models both in terms of its design as well as its conceptual approach to international health. As an intergovernmental, centenary organization in health, PAHO allows participants a unique vantage point from which to conceptualize, share experiences and develop projects relevant to international health. Derived from over two decades of experience (1985-2006) training professionals through its predessor Training Program in International Health, the Leaders in International Health Program "Edmundo Granda Ugalde" (LIHP) utilizes an innovative design, virtual and practical learning activities, and a problem-based approach to analyze the main concepts, theories, actors, forces, and processes relevant to international health. In collaboration with PAHO/WHO Representative Offices and national institutions, participants develop country projects based on priority health issues, many of which are integrated into the Organization's technical cooperation and/or implemented by relevant ministries and other entities in their respective countries/subregions. A total of 185 participants representing 31 countries have participated in the LIHP since its inception in 2008, building upon the 187 trained through its predecessor. These initiatives have contributed to the development of health professionals in the Region of the Americas devoted to international health, as well as provided important input towards a conceptual understanding of international health by fostering debate on this issue.

  2. Human exposure to organic arsenic species from seafood.

    Science.gov (United States)

    Taylor, Vivien; Goodale, Britton; Raab, Andrea; Schwerdtle, Tanja; Reimer, Ken; Conklin, Sean; Karagas, Margaret R; Francesconi, Kevin A

    2017-02-15

    Seafood, including finfish, shellfish, and seaweed, is the largest contributor to arsenic (As) exposure in many human populations. In contrast to the predominance of inorganic As in water and many terrestrial foods, As in marine-derived foods is present primarily in the form of organic compounds. To date, human exposure and toxicological assessments have focused on inorganic As, while organic As has generally been considered to be non-toxic. However, the high concentrations of organic As in seafood, as well as the often complex As speciation, can lead to complications in assessing As exposure from diet. In this report, we evaluate the presence and distribution of organic As species in seafood, and combined with consumption data, address the current capabilities and needs for determining human exposure to these compounds. The analytical approaches and shortcomings for assessing these compounds are reviewed, with a focus on the best practices for characterization and quantitation. Metabolic pathways and toxicology of two important classes of organic arsenicals, arsenolipids and arsenosugars, are examined, as well as individual variability in absorption of these compounds. Although determining health outcomes or assessing a need for regulatory policies for organic As exposure is premature, the extensive consumption of seafood globally, along with the preliminary toxicological profiles of these compounds and their confounding effect on assessing exposure to inorganic As, suggests further investigations and process-level studies on organic As are needed to fill the current gaps in knowledge.

  3. HUMAN RESOURCES AND HUMAN RESOURCES STRATEGY – STRATEGIC PARTNERS OF AN ORGANIZATION

    Directory of Open Access Journals (Sweden)

    MUNTEANU ANCA-IOANA

    2015-03-01

    Full Text Available This work is purely theoretical, based on information in the literature, but also on their correlations. The text does not have a generalized, but are personal opinions and conclusions. The objective of this paper is to present particular emphasis to be placed today on the implications of human resources of an organization and human resources strategy have on vital processes within any organization, namely strategic planning, implementing changes and achieve competitive advantage. Organizations should have easily adaptable employees with skills needed to meet customer needs and adapt to permanent changes in the environment in real time. The goal of any organization is to attract more customers to get a favorable market position and competitive advantage against competitors. To achieve these goals, the role and importance of human resources in an organization has evolved into a considerably. Being accepted as a strategic partners of the organizations, human resources begin to be involved in determining strategy, decision-making on the organization as a whole. The emphasis in this paper on presenting the importance of human resources and human resources strategy in an organization, the special role that they have in supporting the overall strategy of the organization through strategic planning, implementation of organizational changes that are so necessary to adapt company's current customer requirements, can be a focal point for business and cause awareness among key stakeholders in a company, the need straightening attention to the foregoing

  4. DNA damage in internal organs after cutaneous exposure to sulphur mustard

    Energy Technology Data Exchange (ETDEWEB)

    Batal, Mohamed [Laboratoire « Lésions des Acides Nucléiques », Université Joseph Fourier – Grenoble 1/CEA/Institut Nanoscience et Cryogénie/SCIB, UMR-E3, Grenoble (France); Département de Toxicologie et Risques Chimiques, Unité de Brûlure Chimique, Institut de Recherche Biomédicale des Armées, Antenne de La Tronche, BP87, F-38702 La Tronche Cedex (France); Boudry, Isabelle; Mouret, Stéphane; Cléry-Barraud, Cécile; Wartelle, Julien [Département de Toxicologie et Risques Chimiques, Unité de Brûlure Chimique, Institut de Recherche Biomédicale des Armées, Antenne de La Tronche, BP87, F-38702 La Tronche Cedex (France); Bérard, Izabel [Laboratoire « Lésions des Acides Nucléiques », Université Joseph Fourier – Grenoble 1/CEA/Institut Nanoscience et Cryogénie/SCIB, UMR-E3, Grenoble (France); Douki, Thierry, E-mail: thierry.douki@cea.fr [Laboratoire « Lésions des Acides Nucléiques », Université Joseph Fourier – Grenoble 1/CEA/Institut Nanoscience et Cryogénie/SCIB, UMR-E3, Grenoble (France)

    2014-07-01

    Sulphur mustard (SM) is a chemical warfare agent that attacks mainly skin, eye and lungs. Due to its lipophilic properties, SM is also able to diffuse through the skin and reach internal organs. DNA represents one of the most critical molecular targets of this powerful alkylating agent which modifies DNA structure by forming monoadducts and biadducts. These DNA lesions are involved in the acute toxicity of SM as well as its long-term carcinogenicity. In the present work we studied the formation and persistence of guanine and adenine monoadducts and guanine biadducts in the DNA of brain, lungs, kidneys, spleen, and liver of SKH-1 mice cutaneously exposed to 2, 6 and 60 mg/kg of SM. SM-DNA adducts were detected in all studied organs, except in liver at the two lowest doses. Brain and lungs were the organs with the highest level of SM-DNA adducts, followed by kidney, spleen and liver. Monitoring the level of adducts for three weeks after cutaneous exposure showed that the lifetime of adducts were not the same in all organs, lungs being the organ with the longest persistence. Diffusion from skin to internal organs was much more efficient at the highest compared to the lowest dose investigated as the result of the loss of the skin barrier function. These data provide novel information on the distribution of SM in tissues following cutaneous exposures and indicate that brain is an important target. - Highlights: • Sulphur mustard reaches internal organs after skin exposure • Adducts are detected in the DNA of internal organs • Brain is the organ with the highest level of DNA damage • The barrier function of skin is lost at high dose of sulphur mustard • DNA adducts persist in organs for 2 or 3 weeks.

  5. International Organizations, Changing Governance and China's Policy Making in Higher Education: An Analysis of the World Bank and the World Trade Organization

    Science.gov (United States)

    Yang, Rui

    2010-01-01

    In a context of intensified globalization, the importance of international governmental organizations and non-governmental organizations as influencers and shapers of the global environment is becoming prominent. Participation in international organizations leads to active incorporation of nation-states with worldwide connotations. In higher…

  6. Gene profile identifies zinc transporters differentially expressed in normal human organs and human pancreatic cancer.

    Science.gov (United States)

    Yang, J; Zhang, Y; Cui, X; Yao, W; Yu, X; Cen, P; Hodges, S E; Fisher, W E; Brunicardi, F C; Chen, C; Yao, Q; Li, M

    2013-03-01

    Deregulated expression of zinc transporters was linked to several cancers. However, the detailed expression profile of all human zinc transporters in normal human organs and in human cancer, especially in pancreatic cancer is not available. The objectives of this study are to investigate the complete expression patterns of 14 ZIP and 10 ZnT transporters in a large number of normal human organs and in human pancreatic cancer tissues and cell lines. We examined the expression patterns of ZIP and ZnT transporters in 22 different human organs and tissues, 11 pairs of clinical human pancreatic cancer specimens and surrounding normal/benign tissues, as well as 10 established human pancreatic cancer cell lines plus normal human pancreatic ductal epithelium (HPDE) cells, using real time RT-PCR and immunohistochemistry. The results indicate that human zinc transporters have tissue specific expression patterns, and may play different roles in different organs or tissues. Almost all the ZIPs except for ZIP4, and most ZnTs were down-regulated in human pancreatic cancer tissues compared to the surrounding benign tissues. The expression patterns of individual ZIPs and ZnTs are similar among different pancreatic cancer lines. Those results and our previous studies suggest that ZIP4 is the only zinc transporter that is significantly up-regulated in human pancreatic cancer and might be the major zinc transporter that plays an important role in pancreatic cancer growth. ZIP4 might serve as a novel molecular target for pancreatic cancer diagnosis and therapy.

  7. Tropospheric Chemistry of Internally Mixed Sea Salt and Organic Particles: Surprising Reactivity of NaCl with Weak Organic Acids

    Energy Technology Data Exchange (ETDEWEB)

    Laskin, Alexander; Moffet, Ryan C.; Gilles, Marry K.; Fast, Jerome D.; Zaveri, Rahul A.; Wang, Bingbing; Nigge, P.; Shutthanandan, Janani I.

    2012-08-03

    Chemical imaging analysis of internally mixed sea salt/organic particles collected on board the Department of Energy (DOE) G-1 aircraft during the 2010 Carbonaceous Aerosols and Radiative Effects Study (CARES) was performed using electron microscopy and X-ray spectro-microscopy techniques. Substantial chloride depletion in aged sea salt particles was observed, which could not be explained by the known atmospheric reactivity of sea salt with inorganic nitric and sulfuric acids. We present field evidence that chloride components in sea salt particles may effectively react with organic acids releasing HCl gas to the atmosphere, leaving behind particles depleted in chloride and enriched in the corresponding organic salts. While formation of the organic salts products is not thermodynamically favored for bulk aqueous chemistry, these reactions in aerosol are driven by high volatility and irreversible evaporation of the HCl product from drying particles. These field observations were corroborated in a set of laboratory experiments where NaCl particles mixed with organic acids were found to be depleted in chloride. Combined together, the results indicate substantial chemical reactivity of sea salt particles with secondary organics that has been largely overlooked in the atmospheric aerosol chemistry. Atmospheric aging, and especially hydration-dehydration cycles of mixed sea salt/organic particles may result in formation of organic salts that will modify acidity, hygroscopic and optical properties of aged particles.

  8. Human endothelial progenitor cells internalize high-density lipoprotein.

    Science.gov (United States)

    Srisen, Kaemisa; Röhrl, Clemens; Meisslitzer-Ruppitsch, Claudia; Ranftler, Carmen; Ellinger, Adolf; Pavelka, Margit; Neumüller, Josef

    2013-01-01

    Endothelial progenitor cells (EPCs) originate either directly from hematopoietic stem cells or from a subpopulation of monocytes. Controversial views about intracellular lipid traffic prompted us to analyze the uptake of human high density lipoprotein (HDL), and HDL-cholesterol in human monocytic EPCs. Fluorescence and electron microscopy were used to investigate distribution and intracellular trafficking of HDL and its associated cholesterol using fluorescent surrogates (bodipy-cholesterol and bodipy-cholesteryl oleate), cytochemical labels and fluorochromes including horseradish peroxidase and Alexa Fluor® 568. Uptake and intracellular transport of HDL were demonstrated after internalization periods from 0.5 to 4 hours. In case of HDL-Alexa Fluor® 568, bodipy-cholesterol and bodipy-cholesteryl oleate, a photooxidation method was carried out. HDL-specific reaction products were present in invaginations of the plasma membrane at each time of treatment within endocytic vesicles, in multivesicular bodies and at longer periods of uptake, also in lysosomes. Some HDL-positive endosomes were arranged in form of "strings of pearl"- like structures. HDL-positive multivesicular bodies exhibited intensive staining of limiting and vesicular membranes. Multivesicular bodies of HDL-Alexa Fluor® 568-treated EPCs showed multilamellar intra-vacuolar membranes. At all periods of treatment, labeled endocytic vesicles and organelles were apparent close to the cell surface and in perinuclear areas around the Golgi apparatus. No HDL-related particles could be demonstrated close to its cisterns. Electron tomographic reconstructions showed an accumulation of HDL-containing endosomes close to the trans-Golgi-network. HDL-derived bodipy-cholesterol was localized in endosomal vesicles, multivesicular bodies, lysosomes and in many of the stacked Golgi cisternae and the trans-Golgi-network Internalized HDL-derived bodipy-cholesteryl oleate was channeled into the lysosomal intraellular

  9. Human endothelial progenitor cells internalize high-density lipoprotein.

    Directory of Open Access Journals (Sweden)

    Kaemisa Srisen

    Full Text Available Endothelial progenitor cells (EPCs originate either directly from hematopoietic stem cells or from a subpopulation of monocytes. Controversial views about intracellular lipid traffic prompted us to analyze the uptake of human high density lipoprotein (HDL, and HDL-cholesterol in human monocytic EPCs. Fluorescence and electron microscopy were used to investigate distribution and intracellular trafficking of HDL and its associated cholesterol using fluorescent surrogates (bodipy-cholesterol and bodipy-cholesteryl oleate, cytochemical labels and fluorochromes including horseradish peroxidase and Alexa Fluor® 568. Uptake and intracellular transport of HDL were demonstrated after internalization periods from 0.5 to 4 hours. In case of HDL-Alexa Fluor® 568, bodipy-cholesterol and bodipy-cholesteryl oleate, a photooxidation method was carried out. HDL-specific reaction products were present in invaginations of the plasma membrane at each time of treatment within endocytic vesicles, in multivesicular bodies and at longer periods of uptake, also in lysosomes. Some HDL-positive endosomes were arranged in form of "strings of pearl"- like structures. HDL-positive multivesicular bodies exhibited intensive staining of limiting and vesicular membranes. Multivesicular bodies of HDL-Alexa Fluor® 568-treated EPCs showed multilamellar intra-vacuolar membranes. At all periods of treatment, labeled endocytic vesicles and organelles were apparent close to the cell surface and in perinuclear areas around the Golgi apparatus. No HDL-related particles could be demonstrated close to its cisterns. Electron tomographic reconstructions showed an accumulation of HDL-containing endosomes close to the trans-Golgi-network. HDL-derived bodipy-cholesterol was localized in endosomal vesicles, multivesicular bodies, lysosomes and in many of the stacked Golgi cisternae and the trans-Golgi-network Internalized HDL-derived bodipy-cholesteryl oleate was channeled into the lysosomal

  10. Sterols of Pneumocystis carinii hominis Organisms Isolated from Human Lungs

    Science.gov (United States)

    Kaneshiro, Edna S.; Amit, Zunika; Chandra, Jyotsna; Baughman, Robert P.; Contini, Carlo; Lundgren, Bettina

    1999-01-01

    The opportunistic pathogen Pneumocystis carinii causes pneumonia (P. carinii pneumonia, or PCP) in immunocompromised individuals such as AIDS patients. Rat-derived P. carinii carinii organisms have distinct sterols which are not synthesized by mammals and not found in other microbes infecting mammalian lungs. The dominant sterol present in the organism is cholesterol (which is believed to be scavenged from the host), but other sterols in P. carinii carinii have an alkyl group at C-24 of the sterol side chain (C28 and C29 24-alkylsterols) and a double bond at C-7 of the nucleus. Recently, pneumocysterol (C32), which is essentially lanosterol with a C-24 ethylidene group, was detected in lipids extracted from a formalin-fixed human P. carinii-infected lung, and its structures were elucidated by gas-liquid chromatography, mass spectrometry, and nuclear magnetic resonance spectrometry in conjunction with analyses of chemically synthesized authentic standards. The sterol composition of isolated P. carinii hominis organisms has yet to be reported. If P. carinii from animal models is to be used for identifying potential drug targets and for developing chemotherapeutic approaches to clear human infections, it is important to determine whether the 24-alkylsterols of organisms found in rats are also present in organisms in humans. In the present study, sterol analyses of P. carinii hominis organisms isolated from cryopreserved human P. carinii-infected lungs and from bronchoalveolar lavage fluid were performed. Several of the same distinct sterols (e.g., fungisterol and methylcholest-7-ene-3β-ol) previously identified in P. carinii carinii were also present in organisms isolated from human specimens. Pneumocysterol was detected in only some of the samples. PMID:10548595

  11. The World Health Organization and the transition from "international" to "global" public health.

    Science.gov (United States)

    Brown, Theodore M; Cueto, Marcos; Fee, Elizabeth

    2006-01-01

    The term "global health" is rapidly replacing the older terminology of "international health." We describe the role of the World Health Organization (WHO) in both international and global health and in the transition from one to the other. We suggest that the term "global health" emerged as part of larger political and historical processes, in which WHO found its dominant role challenged and began to reposition itself within a shifting set of power alliances. Between 1948 and 1998, WHO moved from being the unquestioned leader of international health to being an organization in crisis, facing budget shortfalls and diminished status, especially given the growing influence of new and powerful players. We argue that WHO began to refashion itself as the coordinator, strategic planner, and leader of global health initiatives as a strategy of survival in response to this transformed international political context.

  12. Docetaxel-Induced Systemic Sclerosis with Internal Organ Involvement Masquerading as Congestive Heart Failure.

    Science.gov (United States)

    Park, Bumsoo; Vemulapalli, Raghavendra C; Gupta, Amit; Shreve, Maria E; Rees, Della A

    2017-01-01

    Systemic sclerosis, or scleroderma, is a complex medical disorder characterized by limited or diffuse skin thickening with frequent involvement of internal organs such as lungs, gastrointestinal tract, or kidneys. Docetaxel is a chemotherapeutic agent which has been associated with cutaneous side effects. An uncommon cutaneous side effect of docetaxel is scleroderma-like skin changes that extend from limited to diffuse cutaneous systemic sclerosis. Several case reports have been published regarding the association of docetaxel and systemic sclerosis. However, those reports demonstrated the association between docetaxel and scleroderma-like skin changes without internal organ involvement. Here, we report a case of systemic sclerosis with pulmonary arterial hypertension and a microangiopathic kidney involvement induced by docetaxel chemotherapy. After an exhaustive literature review, this could be the first case of docetaxel-induced systemic sclerosis involving internal organs.

  13. Docetaxel-Induced Systemic Sclerosis with Internal Organ Involvement Masquerading as Congestive Heart Failure

    Science.gov (United States)

    Vemulapalli, Raghavendra C.; Gupta, Amit; Shreve, Maria E.; Rees, Della A.

    2017-01-01

    Systemic sclerosis, or scleroderma, is a complex medical disorder characterized by limited or diffuse skin thickening with frequent involvement of internal organs such as lungs, gastrointestinal tract, or kidneys. Docetaxel is a chemotherapeutic agent which has been associated with cutaneous side effects. An uncommon cutaneous side effect of docetaxel is scleroderma-like skin changes that extend from limited to diffuse cutaneous systemic sclerosis. Several case reports have been published regarding the association of docetaxel and systemic sclerosis. However, those reports demonstrated the association between docetaxel and scleroderma-like skin changes without internal organ involvement. Here, we report a case of systemic sclerosis with pulmonary arterial hypertension and a microangiopathic kidney involvement induced by docetaxel chemotherapy. After an exhaustive literature review, this could be the first case of docetaxel-induced systemic sclerosis involving internal organs.

  14. Colonization of internal organs by Salmonella Enteritidis in experimentally infected laying hens housed in conventional or enriched cages.

    Science.gov (United States)

    Gast, Richard K; Guraya, Rupa; Jones, Deana R; Anderson, Kenneth E

    2013-02-01

    More human illnesses caused by Salmonella enterica subspecies enterica serovar Enteritidis throughout the world have been linked to the consumption of contaminated eggs than to any other food vehicle. Deposition of this pathogen in the edible contents of eggs occurs when systemic infections of laying hens involve colonization of reproductive organs. In recent years, the consequences of different housing systems for laying flocks have become the focus of international attention from both animal welfare and public health perspectives. Nevertheless, many questions remain unresolved regarding the food safety implications of various laying hen production systems. The present study assessed the effects of 2 different housing types (conventional cages and colony cages enriched with perching, nesting, and scratching areas) on the invasion of internal organs by Salmonella Enteritidis in experimentally infected laying hens. In 2 trials, groups of laying hens housed in each cage system were orally inoculated with doses of 1.0 × 10(7) cfu of Salmonella Enteritidis. At 5 to 6 d postinoculation, hens were euthanized and samples of internal organs were removed for bacteriologic culturing. For both trials combined, Salmonella Enteritidis was recovered from 95.3% of cecal samples, with no significant differences observed between housing systems. However, Salmonella Enteritidis was detected at significantly (P Salmonella Enteritidis.

  15. Evaluation of two human plasma pools as candidate international standard preparations for syphilitic antibodies.

    Science.gov (United States)

    Rigsby, Peter; Ison, Catherine; Brierley, Matthew; Ballard, Ron; Hagedorn, Hans-Jochen; Lewis, David A; Notermans, Daan W; Riis, Jørn; Robertson, Peter; Seppälä, Ilkka J T; Rijpkema, Sjoerd

    2009-08-01

    A collaborative study was designed to asses two freeze-dried human plasma preparations containing anti-Treponema pallidum antibodies, 05/132 and 05/122, for their suitability as international reference reagents for syphilis serology. Both preparations are intended as replacements of the first international standard (IS) for syphilitic serum antibodies (HS). Samples were tested by eight laboratories using the T. pallidum passive particle agglutination assay (TPPA), the venereal disease research laboratory test (VDRL) and the rapid plasma reagin test (RPR). In addition a range of immunoassays was also used. The outcome of the collaborative study revealed that candidate standard 05/132 contains T. pallidum-specific IgG and IgM and is reactive in VDRL or RPR, and that 05/122 contains T. pallidum-specific IgG but is not reactive in either the VDRL or RPR test. Both 05/132 and 05/122 are reactive in the TPPA. On the basis of these results the Expert Committee on Biological Standardization of the World Health Organization designated 05/132 as the 1st IS for human syphilitic plasma IgG and IgM with a unitage of 3 IU per ampoule relative to HS and 05/122 as the 1st IS for human syphilitic plasma IgG with a unitage of 300 mIU per ampoule relative to 05/132.

  16. INTERNALIZATION OF ANTIMICROBIAL PEPTIDE ACIPENSIN 1 INTO HUMAN TUMOR CELLS

    Directory of Open Access Journals (Sweden)

    E. S. Umnyakova

    2016-01-01

    Full Text Available Search for new compounds providing delivery of drugs into infected or neoplastic cells, is an important direction of biomedical research. Cell-penetrating peptides are among those compounds, due to their ability to translocate through membranes of eukaryotic cells, serving as potential carriers of various therapeutic agents to the target cells. The aim of present work was to investigate the ability of acipensin 1, an antimicrobial peptide of innate immune system, for in vitro penetration into human tumor cells. Acipensin 1 is a cationic peptide that we have previously isolated from leukocytes of the Russian sturgeon, Acipenser gueldenstaedtii. Capability of acipensin 1 to enter the human erytroleukemia K-562 cells has been investigated for the first time. A biotechnological procedure for producing a recombinant acipensin 1 peptide has been developed. The obtained peptide was conjugated with a fluorescent probe BODIPY FL. By means of confocal microscopy, we have shown that the tagged acipensin 1 rapidly enters into K-562 cells and can be detected in the intracellular space within 5 min after its addition to the cell culture. Using flow cytometry technique, penetration kinetics of the labeled peptide into K-562 cells (at nontoxic micromolar concentrations has been studied. We have observed a rapid internalization of the peptide to the target cells, thus confirming the results of microscopic analysis, i.e, the labeled acipensin was detectable in K-562 cells as soon as wihin 2-3 seconds after its addition to the incubation medium. The maximum of fluorescence was reached within a period of approx. 45 seconds, with further “plateau” at the terms of >100 seconds following cell stimulation with the test compound. These data support the concept, that the antimicrobial peptides of innate immunity system possess the features of cell-penetrating peptides, and allow us to consider the studied sturgeon peptide a promising template for development of new

  17. Strategies for transforming human service organizations into learning organizations: knowledge management and the transfer of learning.

    Science.gov (United States)

    Austin, Michael J

    2008-01-01

    This analysis describes the nature of a learning organization, defines the boundaries of evidence-informed practice, identifies the elements of knowledge management, and specifies the elements of the transfer of learning. A set of principles are presented to guide managers in transforming human service organizations into learning organizations along with a set of implementation strategies that can inform participants of the values and benefits of knowledge management. This analysis features concepts and principles adapted and synthesized from research in diverse fields, such as evidence-based health care and the for-profit sector related to learning organizations, knowledge management, and the transfer of learning.

  18. The protection of the accused in international criminal law according to the Human Rights Law Standard

    Directory of Open Access Journals (Sweden)

    Karolina Kremens

    2011-12-01

    Full Text Available The presented paper discusses the influence of international human rights law on international criminal law. It tries to give an answer to the question of whether rules protecting the accused in international criminal proceedings meet the human rights law standard provided by international declarations and covenants. Meaning, if the proceedings before the International Criminal Tribunal for Former Yugoslavia (ICTY, International Criminal Tribunal for Rwanda (ICTR and International Criminal Court (ICC meet the standard provided by international human rights law, in particular the International Covenant on Civil and Political Rights. The paper proves that international human rights law has affected international criminal law tremendously. Moreover, it is argued that the protection of the accused in the law of the international courts and tribunals with regard to his rights has improved when compared to the international human rights law standard. In particular the Rome Statute of the ICC provides the accused with the most comprehensive protection. This is especially visible in the case of such rights as the presumption of innocence, right to an interpreter and right to remain silent. Nevertheless, some shortcomings in the law of the ad hoc tribunals and ICC can be observed, in particular when it comes to identifying the commencement of protection of the accused.

  19. International round-robin experiment to test the International Organization for Standardization total-scattering draft standard.

    Science.gov (United States)

    Kadkhoda, P; Müller, A; Ristau, D; Duparré, A; Gliech, S; Lauth, H; Schuhmann, U; Reng, N; Tilsch, M; Schuhmann, R; Amra, C; Deumie, C; Jolie, C; Kessler, H; Lindström, T; Ribbing, C G; Bennett, J M

    2000-07-01

    An international round-robin experiment has been conducted among laboratories in different countries to test the measurement and the data-analysis procedures in the International Organization for Standardization draft standard ISO/DIS 13696 for measuring total scattering from low-scatter laser optics. Ten laboratories measured total backscattering from high-reflectance mirrors, 50% beam splitters, and antireflection-coated windows. Results were sent to the Laser Zentrum Hannover, which acted as coordinator and analyzed all the backscattering data. The results showed that the procedure in the draft standard was useful for measuring and reporting backscattering for low-scatter optics. Problems encountered in the round-robin experiment included the accumulation of particles on the surfaces, particularly on the high-reflectance mirrors.

  20. HUMAN RESOURCES MANAGEMENT EFFICIENCY IN THE MILITARY ORGANIZATION

    OpenAIRE

    Alexandra STANIT; RIZESCU Marius

    2012-01-01

    The effectiveness of resources available to an organization depends to an extent to a more effective use of human resources. From this point of view, people are not only very valuable or precious, but extremely expensive and becoming more expensive, requiring appropriate treatment and efficient use. The successful application of the human resources management implies a performance evaluation system, a system of employee incentives and results rewarding. This management system aims at the cont...

  1. Amsterdam Center for International law: introduction to the Symposium on Responsibility of International Organizations and of (Member) States: attributed or direct responsibility or both?

    NARCIS (Netherlands)

    Kuijper, P.J.

    2010-01-01

    This is the introduction to three articles that resulted from the Symposium on Responsibility of International Organizations and of (Member) States organized by the Amsterdam Center for International Law (ACIL) under direction of Professors André Nollkaemper and Pieter Jan Kuijper in April 2009. The

  2. Erratum to: An International Urogynecological Association (IUGA) / International Continence Society (ICS) joint report on the terminology for female pelvic organ prolapse (POP)

    NARCIS (Netherlands)

    Haylen, Bernard T.; Maher, Christopher F.; Barber, Matthew D.; Camargo, Sérgio; Dandolu, Vani; Digesu, Alex; Goldman, Howard B.; Huser, Martin; Milani, Alfredo L.; Moran, Paul A.; Schaer, Gabriel N.; Withagen, Mariëlla I J

    2016-01-01

    Introduction: The terminology for female pelvic floor prolapse (POP) should be defined and organized in a clinically-based consensus Report. Methods: This Report combines the input of members of two International Organizations, the International Urogynecological Association (IUGA) and the Internatio

  3. Structural organization and morphometric parameters in system of excretory ducts of human labial glands

    OpenAIRE

    Pilyugin A.V.; Sherstuk O.A.; Deynega T.F.; Ivanchenko N.I.

    2008-01-01

    With the aim of conformity and structural features revealing and space organization of excretory ducts of small salivary glands system of human being, the histology of wall of labial excretory ducts is studied, morphometry of their major size is carried out (external diameter, space, width of wall). In the system of excretory ducts of labial gland of human being, the change of size of their external and internal diameter is revealed, which is seen on the cutting and 3-D models such local shar...

  4. Ethical Issues of Transplanting Organs from Transgenic Animals into Human Beings

    Directory of Open Access Journals (Sweden)

    Shima Behnam Manesh

    2014-04-01

    Full Text Available One of the most important applications of transgenic animals for medical purposes is to transplant their organs into human’s body, an issue which has caused a lot of ethical and scientific discussions. we can divide the ethical arguments to two comprehensive groups; the first group which is known as deontological critiques (related to the action itself regardless of any results pointing the human or animal and the second group, called the consequentialist critiques (which are directly pointing the consequences of the action. The latter arguments also can be divided to two subgroups. In the first one which named anthropocentrism, just humankind has inherent value in the moral society, and it studies the problem just from a human-based point of view while in second named, biocentrism all the living organism have this value and it deals specially with the problem from the animal-based viewpoint. In this descriptive-analytic study, ethical issues were retrieved from books, papers, international guidelines, thesis, declarations and instructions, and even some weekly journals using keywords related to transgenic animals, organ, and transplantation. According to the precautionary principle with the strong legal and ethical background, due to lack of accepted scientific certainties about the safety of the procedure, in this phase, transplanting animal’s organs into human beings have the potential harm and danger for both human and animals, and application of this procedure is unethical until the safety to human will be proven.

  5. Estimation of internal organ motion-induced variance in radiation dose in non-gated radiotherapy

    Science.gov (United States)

    Zhou, Sumin; Zhu, Xiaofeng; Zhang, Mutian; Zheng, Dandan; Lei, Yu; Li, Sicong; Bennion, Nathan; Verma, Vivek; Zhen, Weining; Enke, Charles

    2016-12-01

    In the delivery of non-gated radiotherapy (RT), owing to intra-fraction organ motion, a certain degree of RT dose uncertainty is present. Herein, we propose a novel mathematical algorithm to estimate the mean and variance of RT dose that is delivered without gating. These parameters are specific to individual internal organ motion, dependent on individual treatment plans, and relevant to the RT delivery process. This algorithm uses images from a patient’s 4D simulation study to model the actual patient internal organ motion during RT delivery. All necessary dose rate calculations are performed in fixed patient internal organ motion states. The analytical and deterministic formulae of mean and variance in dose from non-gated RT were derived directly via statistical averaging of the calculated dose rate over possible random internal organ motion initial phases, and did not require constructing relevant histograms. All results are expressed in dose rate Fourier transform coefficients for computational efficiency. Exact solutions are provided to simplified, yet still clinically relevant, cases. Results from a volumetric-modulated arc therapy (VMAT) patient case are also presented. The results obtained from our mathematical algorithm can aid clinical decisions by providing information regarding both mean and variance of radiation dose to non-gated patients prior to RT delivery.

  6. The Organization of the Internal Irradiation Monitoring System in Conditions of Nonstandard Radionuclide Intakes

    Science.gov (United States)

    Ovchinnikov, A. V.; Izmestyev, K. M.; Demyanyuk, D. G.; Krivoshein, D. D.; Poluektov, S. Yu

    2016-06-01

    Scientific knowledge presently available in the area of monitoring the internal radiation due to nonstandard radionuclide intakes gives no way of identifying the location and nature of intakes in a reasonably accurate and expeditious manner. Both theoretical models and practical methods of personnel internal radiation screening exhibit the lack of research. To this end, the present paper deals with the experience gained by the SGChE in the monitoring of the nonstandard radionuclide penetration into internals and tissues of the personnel. It provides recommendations for the organization and implementation of such monitoring procedures, and describes the practical method for the vulnerary intake containment.

  7. Grossman-Hart (1986) Goes Global: Incomplete Contracts, Property Rights, and the International Organization of Production

    OpenAIRE

    Antras, Pol

    2011-01-01

    I survey the influence of Grossman and Hart's (1986) “The Costs and Benefits of Ownership: A Theory of Vertical and Lateral Integration,†94 Journal of Political Economy 691–719.) seminal paper in the field of International Trade. I discuss the implementation of the theory in open-economy environments and its implications for the international organization of production and the structure of international trade flows. I also review empirical work suggestive of the empirical relevance of t...

  8. National and International Standardization (International Organization for Standardization and European Committee for Standardization Relevant for Sustainability in Construction

    Directory of Open Access Journals (Sweden)

    Renata Morbiducci

    2010-12-01

    Full Text Available Sustainability in construction has a short history in terms of principles, standardizations and applications. From the Brundtland Report “Our Common Future”, a new vision of the resource deficits, climate impacts and the social responsibility gave growth to the idea of sustainability also in design and construction. Consequently, in around 2000, the international and national organizations for standardization started to develop standards for the application of sustainable principles. This paper gives an overview of existing and planned standards, and examples on how to use them as a framework for the development of methods and tools for assessment.

  9. FUNCTIONS OF SOCIAL RELATIONSHIPS IN THE ORGANIZING OF AN INTERNATIONAL JOINT VENTURE

    Directory of Open Access Journals (Sweden)

    Daniel Serafim BROTEA

    2009-12-01

    Full Text Available This paper examines the use of social relationships in the organizing of a business network in the case of an international joint venture (IJV developing over time. The organizing process and the multicultural setting of the international joint venture emphasize the actions of and interactions between individuals from various organizations. The IJV-managers' use of their social relationships in business organizing is explored through analysis of narratives of IJVmanagers in a longitudinal single case to provide empirically grounded theory. From the in-depth interviews with IJV-managers the business relationships are identified as characterized by four possible levels of interpersonal relationships whose type influences the functions of the relationships and visa versa. One business relationship may contain only one or many of these interpersonal levels and an effective business relationship contains the appropriate interpersonal level for the business issue at hand.

  10. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    Science.gov (United States)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are an important astrobiology focus. The ORganics Exposure in Orbit (OREOcube) experiment will investigate, in real time, chemical changes in organic compounds exposed to low Earth orbit radiation conditions on an International Space Station (ISS) external platform. OREOcube is packaged as an identical pair of 10-cm cube instruments, each weighing electronics, microcontroller, and data storage to make each cube an autonomous stand-alone instrument package requiring only a standard power and data interface. We have characterized the influence of mineralogically relevant inorganic materials on the stability, modification, and degradation of the organic molecules under ground laboratory experimental conditions. The results of our laboratory experiments will be used as the basis for the selection of samples for further investigations on the OREOcube ISS experiment. OREOcube is an international collaboration between the European Space Agency, the National Aeronautics and Space Administration, and University partners.

  11. Second Conference of Staff Associations of International Organizations held at CERN

    CERN Multimedia

    2001-01-01

    Representatives from the twenty organizations that attended the staff associations conference. The second Conference of Staff Associations of International Organizations (CSAIO2) just took place here at CERN on Thursday and Friday, the 25th-26th of October. Associations and Unions of twenty two organizations of greatly varying sizes were present, from the gargantuan European Commission to the smaller Commonwealth Secretariat. But size mattered not at all once the conference got under way and everyone started sharing ideas and experiences regarding the promotion and defense of staff interests. In fact, differences in size, mission and history made the Conference all the more interesting. Specific topics which the conference covered were internal appeal and grievance procedures, working time, and advancement & promotion systems. 'The information exchanged was of very high value' said Jean-Pol Matheys, President of the CERN Staff Association, which organized this event, 'I think participants left very...

  12. Cultural and psychological dimensions of human organ transplantation.

    Science.gov (United States)

    Marshall, P A; Daar, A S

    1998-01-01

    Human organ transplantation is practiced in local cultural worlds that shape beliefs about appropriate conduct for its development and application. The psychological response of individuals to the transplant experience mediate and condition its life-changing force in the context of family and community. In this paper, three cases are examined to illustrate the impact of cultural and psychological influences on human organ replacement therapies. First, we explore brain death and its implications for the definition of death and the procurement of organs. A case example from Japan provides the framework for addressing the cultural foundations that contribute to perceptions of personhood and the treatment of the body. Second, we examine marketing incentives for organ donation using a case from India where, until recently, explicit forms of financial incentives have played a role in the development of renal transplantation involving non-related living donors. Third, we focus on the psychological remifications of organ transplantation using a case that demonstrates the profound experience of being the recipient of the "gift of life". Resolution of scientific and ethical challenges in the field of organ transplantation must consider the complex and significant impact of cultural and psychological factors on organ replacement therapies.

  13. The economics and ethics of markets for human organs.

    Science.gov (United States)

    Hansmann, H

    1989-01-01

    In 1984, federal legislation outlawing payment for human organs for transplantation was adopted after only cursory discussion of the underlying policy issues. More considered analysis suggests that this prohibition may be overly broad. It appears possible to design suitably regulated market-type approaches to the acquisition and allocation of cadaveric organs (and perhaps of organs from living donors as well) that will be neither unduly offensive to ethical sensibilities nor easily abused and that may yield significant improvements over the existing system of organ procurement, which presents important ethical and practical problems of its own. Moreover, whatever ultimate judgment we reach concerning the merits of markets for transplantable organs, analysis of the sources of the initial moral resistance to the commercialization that lies behind measures such as the 1984 legislation offers insights into the respective roles of market and nonmarket institutions in general.

  14. Human Rights and Education. Comparative & International Education Series, Volume 3.

    Science.gov (United States)

    Tarrow, Norma Bernstein, Ed.

    This book discusses the relationship between human rights and education. Education is discussed both within the context of human rights, and as the ultimate sanction and guarantee of all human rights. Part 1, "Education as a Human Right," is comprised of the following chapters: (1) "Human Rights and Education: An Overview" (D.…

  15. INTERNATIONAL ORGANIZATIONS IN BRAZIL AND PORTUGAL: A (CONFORMATION TOWARD THE CAPITAL

    Directory of Open Access Journals (Sweden)

    Camila Azevedo Souza

    2014-06-01

    Full Text Available This study analyzes the action of international organizations in Brazil and Portugal, observing its implications for education policies in these two social scenarios. Guided by the historical materialism method and, more specifically, by the formulations of Antonio Gramsci, this work intends to highlight the hegemony relations that cross the educational guidelines of these organizations by identifying the application of bourgeois conception of world along the educational projects promoted by the dominant class.

  16. International Human Resource Management Education: A Survey of HR Professionals, Suggestions for Skill Dissemination.

    Science.gov (United States)

    Barclay, Lizabeth A.; Wagner-Marsh, Fraya; Loewe, G. Michael

    2002-01-01

    Surveyed a human resource professional association about training and interest in international human resources management. Based on results, offers recommendations for expanding coverage of this topic in credit and non-credit courses. (EV)

  17. Where do human organs come from? Trends of generalized and restricted altruism in organ donations.

    Science.gov (United States)

    Boas, Hagai

    2011-11-01

    The supply of human organs for transplantation is undergoing a dramatic transformation. Using data from 30 countries for the years 1995-2007, this paper suggests that organ supply today is more dependent on direct donations than on the collective organ pool. This trend is analyzed by studying different modes of altruism: "generalized altruism" relates to the procurement of organs through a one-for-all collectivized system of donations whereas "restricted altruism" relates to one-to-one donations with organs considered personal gifts. The data suggest that transplants are becoming less and less social goods and more and more personal gifts. This trend is documented and discussed in light of the linkage that social scientists hypothesize between altruism and social solidarity. Whereas altruism is conceived as generating social solidarity, the rise in direct organ donations restricts the effect of altruism to one-to-one interactions rather than one-for-all giving.

  18. Influence Of International Financial And Economic Organizations On The Development Of Russian Law

    Directory of Open Access Journals (Sweden)

    Dmitriy A. Pashencev

    2015-03-01

    Full Text Available In the present article characteristics and patterns of the impact of the international financial and economic organizations on the development of Russian law in the present-day conditions are described. It is noted, that the international financial and economic organizations firmly rooted in the world. They are based on international agreements, which participants could be also non-State structures. The role of international financial and economic organizations in the development of the negative effects of globalization and the production of global financial crisis is considered. The necessity to change the economic course of our country was proved because of the crisis and sanctions, as well as the need to find new ways of structuring the international financial and economic space, including the basis of the new inter-state unions and a new reserve currency. It is shown that the Russian domestic law should be the barrier against the destabilizing influence of transnational corporations. Legal acts of the Russian Federation defining the terms and scope of cooperation with international economic and financial organizations were analyzed. It is noted, that in accordance with applicable Russian legislation, international financial institutions have the right to invest in Russian companies, including and strategic. It is proved that the situation in the modern world and its negative manifestations determine the need for a number of effective measures and require changes in legislation. It is necessary to make changes in the current Russian legislation, first of all, investment, banking, trade, etc., to develop effective legal mechanisms for the protection of domestic producers and the national market from the expansion of multinational corporations.

  19. Regulating private human suborbital flight at the international and European level: Tendencies and suggestions

    Science.gov (United States)

    Masson-Zwaan, Tanja; Moro-Aguilar, Rafael

    2013-12-01

    In the context of the FAST20XX project (Future High-Altitude High-Speed Transport) that started in 2009 under the 7th Framework Programme of the European Union (EU), the authors reexamined the legal status of private human suborbital flight, and researched whether it might be regulated as aviation or as spaceflight. International space law is ambiguous as to accommodating suborbital activities. While some provisions of the UN outer space treaties would seem to exclude them, generally there is not any explicit condition in terms of reaching orbit as a requirement for application. International air law presents equal difficulties in dealing with this activity. The classic definition of "aircraft" as contained in the Annexes to the Chicago Convention does not really encompass the kind of rocket-powered vehicles that are envisaged here. As a result, it is unclear whether the United Nations Committee on the Peaceful Uses of Outer Space (COPUOS), the International Civil Aviation Organization (ICAO), or both could be involved in an eventual international regulation of suborbital flight. In the absence of a uniform international regime, each state has the sovereign right to regulate human suborbital flights operating within its airspace. So far, two practical solutions have been realised or proposed, and will be analyzed. On the one hand, the USA granted power for regulation and licensing over private human suborbital flight to the Office of Commercial Space Transportation of the Federal Aviation Administration (FAA/AST). Subsequent regulations by the FAA have set out a series of requirements for companies that want to operate these flights, enabling a market to develop. On the other side of the Atlantic, both the European Space Agency (ESA) and a group of representatives of the European Aviation Safety Agency (EASA) of the European Union (EU) seem to rather regard this activity as aviation, potentially subject to the regulation and certification competences of EASA

  20. Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs

    Science.gov (United States)

    Oleaga, Carlota; Bernabini, Catia; Smith, Alec S. T.; Srinivasan, Balaji; Jackson, Max; McLamb, William; Platt, Vivien; Bridges, Richard; Cai, Yunqing; Santhanam, Navaneetha; Berry, Bonnie; Najjar, Sarah; Akanda, Nesar; Guo, Xiufang; Martin, Candace; Ekman, Gail; Esch, Mandy B.; Langer, Jessica; Ouedraogo, Gladys; Cotovio, Jose; Breton, Lionel; Shuler, Michael L.; Hickman, James J.

    2016-02-01

    We report on a functional human model to evaluate multi-organ toxicity in a 4-organ system under continuous flow conditions in a serum-free defined medium utilizing a pumpless platform for 14 days. Computer simulations of the platform established flow rates and resultant shear stress within accepted ranges. Viability of the system was demonstrated for 14 days as well as functional activity of cardiac, muscle, neuronal and liver modules. The pharmacological relevance of the integrated modules were evaluated for their response at 7 days to 5 drugs with known side effects after a 48 hour drug treatment regime. The results of all drug treatments were in general agreement with published toxicity results from human and animal data. The presented phenotypic culture model exhibits a multi-organ toxicity response, representing the next generation of in vitro systems, and constitutes a step towards an in vitro “human-on-a-chip” assay for systemic toxicity screening.

  1. The evolution of human rights in World Health Organization policy and the future of human rights through global health governance.

    Science.gov (United States)

    Meier, B M; Onzivu, W

    2014-02-01

    The World Health Organization (WHO) was intended to serve at the forefront of efforts to realize human rights to advance global health, and yet this promise of a rights-based approach to health has long been threatened by political constraints in international relations, organizational resistance to legal discourses, and medical ambivalence toward human rights. Through legal research on international treaty obligations, historical research in the WHO organizational archives, and interview research with global health stakeholders, this research examines WHO's contributions to (and, in many cases, negligence of) the rights-based approach to health. Based upon such research, this article analyzes the evolving role of WHO in the development and implementation of human rights for global health, reviews the current state of human rights leadership in the WHO Secretariat, and looks to future institutions to reclaim the mantle of human rights as a normative framework for global health governance. Copyright © 2013 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  2. Touch five factors to growing and leading a human organization

    CERN Document Server

    Maffin, Tod

    2014-01-01

    For better or worse, digital business has fundamentally changed how organizations hire, market their services, and connect with stakeholders. The problem is, in an effort to use technology to connect more effectively, we have lost the humanity - that critical person-to-person connection. This book will show you how to restore that connection.

  3. Repair pathways evident in human liver organ slices

    NARCIS (Netherlands)

    Vickers, Alison E. M.; Fisher, Robyn; Olinga, Peter; Dial, Sharon

    2011-01-01

    The extension of human liver slice culture viability for several days broadens the potential of this ex vivo model for characterizing pathways of organ injury and repair, and allows for the multiple dosing of compounds. Extended viability is demonstrated by continued synthesis of GSH and ATP, and ma

  4. Impact of Internal Marketing on Employees' Customer Orientation in Social Security Organization of Gilan

    Directory of Open Access Journals (Sweden)

    Rashid Shadab Jouposhti

    2016-12-01

    Full Text Available With increasing completion between public and private insurance companiesand Social Security Organization as the greatest insurance organization the country, mangers of this organization inevitably seek for the ways to acquire higher customer satisfaction and loyalty so as to obtain and retain higher share of insurers. Meanwhile, role of employees in retention and increasing insurers is evident to all. Satisfied employees can focus their entire attempt for absorbing and retaining customer satisfaction. Internal marketing is the concept which can help Social Security Organization in gaining the goals. Thus, current research was conducted aiming at investigating impact of internal marketing on employees’ customer orientation in Social Security Organization of Gilanprovince. Descriptive-survey research method was used based on structural equation modeling which is recognized as a model for indicating internal marketing impact on customer orientation considering reviewed literature and research hypotheses, fit of which is suitable according to LISREL8 8.5 output. In the current research, internal marketing is considered asindependentvariable and costumer orientation is considered asdependentvariable and organizational commitment acts role as mediator variable. Stratified random sampling method was used for sampling in this research and field study and questionnaire was used for data collection. Statistical population included employees of Social Security Organization of Gilanprovince (N = 677. Following distribution of questionnaires, 244 perfect ones were collected. Research hypotheses were tested using structural equations method. Following analysis of questionnaire data, all research hypotheses were supported and it was shown that organizational commitment plays intermediary role in relationship between internal marketing and customer orientation

  5. Conceptualizing Human Microbiota: From Multicelled Organ to Ecological Community

    Directory of Open Access Journals (Sweden)

    Betsy Foxman

    2008-01-01

    Full Text Available The microbiota of a typical, healthy human contains 10 times as many cells as the human body and incorporates bacteria, viruses, archea, protozoans, and fungi. This diverse microbiome (the collective genomes of the microbial symbionts that inhabit a human host is essential for human functioning. We discuss the unstated assumptions and implications of current conceptualizations of human microbiota: (1 a single unit that interacts with the host and the external environment; a multicelled organ; (2 an assemblage of multiple taxa, but considered as a single unit in its interactions with the host; (3 an assemblage of multiple taxa, which each interacts with the host and the environment independently; and (4 a dynamic ecological community consisting of multiple taxa each potentially interacting with each other, the host, and the environment. Each conceptualization leads to different predictions, methodologies, and research strategies.

  6. To Share or Not to Share? The Allocation of Responsibility between International Organizations and Their Member States

    NARCIS (Netherlands)

    Ahlborn, C.

    2013-01-01

    This paper will discuss the costs and benefits of sharing responsibility between states and international organizations for their own internationally wrongful acts. Rules on shared responsibility are sparse in the existing law of international responsibility as codified by the International Law Comm

  7. Chapter 5: Organizational structures suited to ISPRM's evolving role as an international non-governmental organization in official relation with the world health organization.

    Science.gov (United States)

    von Groote, Per M; Reinhardt, Jan D; Gutenbrunner, Christoph; DeLisa, Joel A; Melvin, John L; Bickenbach, Jerome E; Stucki, Gerold

    2009-09-01

    International non-governmental organizations (NGOs) in official relation with the World Health Organization (WHO) face organizational challenges against the background of legitimate representation of their membership and accountable procedures within the organization. Moreover, challenges arise in the light of such an international NGO's civil societal mandate to help reach the "health-for-all" goals as defined by WHO and to facilitate the implementation of the United Nations (UN) Convention on the Rights of Persons with Disabilities. The objective of this paper is to examine how such an international NGO using the International Society of Physical and Rehabilitation Medicine (ISPRM) as a case in point can address these challenges. The specific aims are to analyse ISPRM's structures and procedures of internal organs and external relations and to develop solutions. These possible solutions will be presented as internal organizational scenarios and a yearly schedule of meetings closely aligned to that of WHO to facilitate an efficient internal and external interaction.

  8. The use of CT density changes at internal tissue interfaces to correlate internal organ motion with an external surrogate

    Energy Technology Data Exchange (ETDEWEB)

    Gaede, Stewart; Yu, Edward; Van Dyk, Jake; Battista, Jerry [Radiation Oncology Program, London Regional Cancer Program, London, Ontario (Canada); Carnes, Gregory; Lee, Ting-Yim [Department of Medical Biophysics, University of Western Ontario, London, Ontario (Canada)

    2009-01-21

    The purpose of this paper is to describe a non-invasive method to monitor the motion of internal organs affected by respiration without using external markers or spirometry, to test the correlation with external markers, and to calculate any time shift between the datasets. Ten lung cancer patients were CT scanned with a GE LightSpeed Plus 4-Slice CT scanner operating in a cine mode. We retrospectively reconstructed the raw CT data to obtain consecutive 0.5 s reconstructions at 0.1 s intervals to increase image sampling. We defined regions of interest containing tissue interfaces, including tumour/lung interfaces that move due to breathing on multiple axial slices and measured the mean CT number versus respiratory phase. Tumour motion was directly correlated with external marker motion, acquired simultaneously, using the sample coefficient of determination, r{sup 2}. Only three of the ten patients showed correlation higher than r{sup 2} = 0.80 between tumour motion and external marker position. However, after taking into account time shifts (ranging between 0 s and 0.4 s) between the two data sets, all ten patients showed correlation better than r{sup 2} = 0.8. This non-invasive method for monitoring the motion of internal organs is an effective tool that can assess the use of external markers for 4D-CT imaging and respiratory-gated radiotherapy on a patient-specific basis.

  9. Self-organizing human cardiac microchambers mediated by geometric confinement

    Science.gov (United States)

    Ma, Zhen; Wang, Jason; Loskill, Peter; Huebsch, Nathaniel; Koo, Sangmo; Svedlund, Felicia L.; Marks, Natalie C.; Hua, Ethan W.; Grigoropoulos, Costas P.; Conklin, Bruce R.; Healy, Kevin E.

    2015-07-01

    Tissue morphogenesis and organ formation are the consequences of biochemical and biophysical cues that lead to cellular spatial patterning in development. To model such events in vitro, we use PEG-patterned substrates to geometrically confine human pluripotent stem cell colonies and spatially present mechanical stress. Modulation of the WNT/β-catenin pathway promotes spatial patterning via geometric confinement of the cell condensation process during epithelial-mesenchymal transition, forcing cells at the perimeter to express an OCT4+ annulus, which is coincident with a region of higher cell density and E-cadherin expression. The biochemical and biophysical cues synergistically induce self-organizing lineage specification and creation of a beating human cardiac microchamber confined by the pattern geometry. These highly defined human cardiac microchambers can be used to study aspects of embryonic spatial patterning, early cardiac development and drug-induced developmental toxicity.

  10. 31 CFR 597.506 - Official activities of certain international organizations; U.S. person employees of certain...

    Science.gov (United States)

    2010-07-01

    ..., and Statements of Licensing Policy § 597.506 Official activities of certain international... International Monetary Fund, the World Food Programme, and the World Health Organization. (c) The retention...

  11. THEORETICAL AND PRACTICAL ASPECTS OF THE INTERNAL AUDIT OF ACCOUNTS RECEIVABLE AND ACCOUNTS PAYABLE IN TRADE ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    Makarenko S. A.

    2014-11-01

    Full Text Available The article is devoted to the internal audit improvement of accounts receivable and accounts payable of wholesale and retail organizations. There is an interpretation of internal audit from two perspectives

  12. THEORETICAL AND PRACTICAL ASPECTS OF THE INTERNAL AUDIT OF ACCOUNTS RECEIVABLE AND ACCOUNTS PAYABLE IN TRADE ORGANIZATIONS

    OpenAIRE

    Makarenko S. A.; Safonova M. F.

    2014-01-01

    The article is devoted to the internal audit improvement of accounts receivable and accounts payable of wholesale and retail organizations. There is an interpretation of internal audit from two perspectives

  13. Prediction of 3D internal organ position from skin surface motion: results from electromagnetic tracking studies

    Science.gov (United States)

    Wong, Kenneth H.; Tang, Jonathan; Zhang, Hui J.; Varghese, Emmanuel; Cleary, Kevin R.

    2005-04-01

    An effective treatment method for organs that move with respiration (such as the lungs, pancreas, and liver) is a major goal of radiation medicine. In order to treat such tumors, we need (1) real-time knowledge of the current location of the tumor, and (2) the ability to adapt the radiation delivery system to follow this constantly changing location. In this study, we used electromagnetic tracking in a swine model to address the first challenge, and to determine if movement of a marker attached to the skin could accurately predict movement of an internal marker embedded in an organ. Under approved animal research protocols, an electromagnetically tracked needle was inserted into a swine liver and an electromagnetically tracked guidewire was taped to the abdominal skin of the animal. The Aurora (Northern Digital Inc., Waterloo, Canada) electromagnetic tracking system was then used to monitor the position of both of these sensors every 40 msec. Position readouts from the sensors were then tested to see if any of the movements showed correlation. The strongest correlations were observed between external anterior-posterior motion and internal inferior-superior motion, with many other axes exhibiting only weak correlation. We also used these data to build a predictive model of internal motion by taking segments from the data and using them to derive a general functional relationship between the internal needle and the external guidewire. For the axis with the strongest correlation, this model enabled us to predict internal organ motion to within 1 mm.

  14. Uncovering the Images and Meanings of International Organizations (IOs) in Higher Education Research

    Science.gov (United States)

    Shahjahan, Riyad A.; Madden, Meggan

    2015-01-01

    Employing Stuart Hall's concept of representation, we examine how international organizations (IOs) are presented in the higher education literature. This paper examines how IOs, such as the World Bank, OECD, and UNESCO, are conceptualized and represented by higher education researchers. We focus on three main representations of IOs in the higher…

  15. 31 CFR 560.539 - Official activities of certain international organizations.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Official activities of certain international organizations. 560.539 Section 560.539 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY...

  16. Uncovering the Images and Meanings of International Organizations (IOs) in Higher Education Research

    Science.gov (United States)

    Shahjahan, Riyad A.; Madden, Meggan

    2015-01-01

    Employing Stuart Hall's concept of representation, we examine how international organizations (IOs) are presented in the higher education literature. This paper examines how IOs, such as the World Bank, OECD, and UNESCO, are conceptualized and represented by higher education researchers. We focus on three main representations of IOs in the higher…

  17. 31 CFR 585.213 - Exemption of activities related to certain international organizations.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exemption of activities related to certain international organizations. 585.213 Section 585.213 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE...

  18. Fuzzy Logic: A New Tool for the Analysis and Organization of International Business Communications.

    Science.gov (United States)

    Sondak, Norman E.; Sondak, Eileen M.

    Classical western logic, built on a foundation of true/false, yes/no, right/wrong statements, leads to many difficulties and inconsistencies in the logical analysis and organization of international business communications. This paper presents the basic principles of classical logic and of fuzzy logic, a type of logic developed to allow for…

  19. 76 FR 40758 - Self-Regulatory Organizations; International Securities Exchange, LLC; Order Approving a Proposed...

    Science.gov (United States)

    2011-07-11

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Order Approving a Proposed Rule Change Relating to Complex Orders July 5, 2011. I. Introduction On May 23, 2011, the...

  20. Use of a professional organization (Council of International Neonatal Nurses) for global networking.

    Science.gov (United States)

    Boykova, Marina

    2010-01-01

    The article illustrates the need to belong to professional specialty organizations to foster collaborations across the globe. The Council of International Neonatal Nurses is the exemplar for this professional group. The personal journey of the author to the global community of neonatal nurses is presented.

  1. 78 FR 70382 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2013-11-25

    ... Exchange is proposing to adopt a definition of expiration date and add language to its rules that reflects... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing...

  2. Between the Local and the Global: Organized Research Units and International Collaborations in the Health Sciences

    Science.gov (United States)

    Sa, Creso M.; Oleksiyenko, Anatoly

    2011-01-01

    Organized research units--also known as centers, institutes, and laboratories--are increasingly prominent in the university. This paper examines how ORUs emerge to promote global agendas and international collaborations in an academic health center in North America. The roles these units play in helping researchers work across institutional and…

  3. DDR and the Internal Organization of Non-State Armed Groups

    Directory of Open Access Journals (Sweden)

    Brian McQuinn

    2016-03-01

    Full Text Available This paper argues that demobilization, disarmament and reintegration (DDR trajectories of non-state armed groups are shaped by a group’s internal organization. Extensive research by political scientists has demonstrated a correlation between internal features of armed groups and their behaviour (e.g. extent of violence used against local communities. I extend this analysis to DDR outcomes by illustrating how two features of an armed group’s internal organization – command profile and financing architecture – influence post-conflict DDR trajectories. To substantiate the theory, four case studies from Colombia, Nepal and Libya are reviewed. The article concludes with the limitations and opportunities of this approach, including the potential of predicting DDR challenges.

  4. Human rights and internal security in Malaysia rhetoric and reality

    OpenAIRE

    Rahim, Noor Hishmuddian

    2006-01-01

    Since 1957, Malaysia has faced external and internal security threats. Over time, Malaysia has succeeded in solving the external threats but internal threats remained. The internal threats have come in many forms, including ethnic conflict, religious extremism and deviationism, and terrorism. Since the safety of the public lies in the hands of the government, measures have been taken to ensure the nation's stability and security, including restriction on civil and political liberties. This th...

  5. The Human Behavioral Ecology of Contemporary World Issues : Applications to Public Policy and International Development.

    Science.gov (United States)

    Tucker, Bram; Rende Taylor, Lisa

    2007-09-01

    Human behavioral ecology (HBE) began as an attempt to explain human economic, reproductive, and social behavior using neodarwinian theory in concert with theory from ecology and economics, and ethnographic methods. HBE has addressed subsistence decision-making, cooperation, life history trade-offs, parental investment, mate choice, and marriage strategies among hunter-gatherers, herders, peasants, and wage earners in rural and urban settings throughout the world. Despite our rich insights into human behavior, HBE has very rarely been used as a tool to help the people with whom we work. This article introduces a special issue of Human Nature which explores the application of HBE to significant world issues through the design and critique of public policy and international development projects. The articles by Tucker, Shenk, Leonetti et al., and Neil were presented at the 104th annual meeting of the American Anthropological Association (AAA) in Washington, D.C., in December 2005, in the first organized session of the nascent Evolutionary Anthropology Section (EAS). We conclude this introduction by summarizing some theoretical challenges to applying HBE, and ways in which evolutionary anthropologists can contribute to solving tough world issues.

  6. Interactions between International Humanitarian Law and International Human Rights Law for the protection of Economic, Social and Cultural Rights

    Directory of Open Access Journals (Sweden)

    Koldo Casla

    2012-01-01

    Full Text Available Economic, Social and Cultural Rights (ESCR are at risk on the battlefield. Thus, human rights lawyers must look for legal means to guarantee the best possible protection of these rights in case of war. It is generally accepted nowadays that both International Humanitarian Law (IHL and International Human Rights Law (IHRL are applicable during armed conflicts. Adding on that and based on a procedural and substantive legal analysis, this paper claims that both IHL and IHRL constantly interact in a relation of synergy or norms.

  7. International Protection of Conscientious Objection: A Comparative Analysis of Human Rights Systems and Perspectives of the Inter- American System

    Directory of Open Access Journals (Sweden)

    María Carmelina Londoño Lázaro

    2016-01-01

    Full Text Available In this article, the recognition of conscientious objection in three international systems for the protection of human rights is analyzed: the Inter-American system, the European system and the United Nations system. The comparative system which is adopted allows for notifications as to common developments, the failings and some tensions which have been confronted by international organs in controversial cases. From this analysis are drawn some lessons which may serve for the guardianship of this law in the Inter- American system.

  8. HUMAN RESOURCE MANAGEMENT AND KNOWLEDGE ORGANIZATION IN ESTONIA AND SLOVENIA

    Directory of Open Access Journals (Sweden)

    Dana Mesner Andolšek

    2015-01-01

    Full Text Available The purpose of the analysis is to make a comparison of HRM practices among New Member States (especially Estonia and Slovenia and how these practices help to create the conditions to develop a knowledge organization. In the paper, the systemic and logical analysis of knowledge management concept and its relations with HRM was used. For empirical research a simple exploratory analysis statistical technique was used on Cranet (the Cranfield Network on Comparative Human Resource Management data on HRM practices across countries was used. Major findings allow stating that two important prerequisites for knowledge organization are met and they are successfully implemented through HRM practices especially in organizations in one country. The empirical research findings showed the trends in global economy and the ability of organizations in the New Member States to adapt through institutionally developed HRM practices.

  9. "Living cadavers" in Bangladesh: bioviolence in the human organ bazaar.

    Science.gov (United States)

    Moniruzzaman, Monir

    2012-03-01

    The technology-driven demand for the extraction of human organs--mainly kidneys, but also liver lobes and single corneas--has created an illegal market in body parts. Based on ethnographic fieldwork, in this article I examine the body bazaar in Bangladesh: in particular, the process of selling organs and the experiences of 33 kidney sellers who are victims of this trade. The sellers' narratives reveal how wealthy buyers (both recipients and brokers) tricked Bangladeshi poor into selling their kidneys; in the end, these sellers were brutally deceived and their suffering was extreme. I therefore argue that the current practice of organ commodification is both exploitative and unethical, as organs are removed from the bodies of the poor by inflicting a novel form of bioviolence against them. This bioviolence is deliberately silenced by vested interest groups for their personal gain.

  10. Cultural pluralism in international human rights law: the role of reservations

    NARCIS (Netherlands)

    Donders, Y.; Vrdoljak, A.F.

    2013-01-01

    This chapter addresses cultural pluralism in international human rights law by analysing one specific aspect of international law, namely reservations to human rights treaties. It has been argued that reservations "…are a legitimate, perhaps even desirable, means of accounting for cultural,

  11. Changes and Challenges in the Flow of International Human Capital: China's Experience

    Science.gov (United States)

    Pan, Su-Yan

    2010-01-01

    This article tracks the changes in the directions of the international flow of Chinese human capital between the 1870s and 2000s. Although many studies on international academic flow adopt the pull-and-push approach, this article argues that the direction of human capital flow is not determined solely by an individual's choice when faced with a…

  12. Book Review: Current Issues in International Human Resource Management and Strategy Research

    DEFF Research Database (Denmark)

    Gretzinger, Susanne

    2009-01-01

    The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer.......The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer....

  13. Divergent Fates of the Medical Humanities in Psychiatry and Internal Medicine: Should Psychiatry Be Rehumanized?

    Science.gov (United States)

    Rutherford, Bret R.; Hellerstein, David J.

    2008-01-01

    Objective: To determine the degree to which the medical humanities have been integrated into the fields of internal medicine and psychiatry, the authors assessed the presence of medical humanities articles in selected psychiatry and internal medicine journals from 1950 to 2000. Methods: The journals searched were the three highest-ranking…

  14. Book Review: Current Issues in International Human Resource Management and Strategy Research

    DEFF Research Database (Denmark)

    Gretzinger, Susanne

    2009-01-01

    The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer.......The article reviews the book "Current Issues in International Human Resource Management and Strategy Research," edited by Marion Festing and Susanne Royer....

  15. The crisis of international human rights law in the global market economy

    NARCIS (Netherlands)

    Augenstein, D.H.

    2014-01-01

    The contribution argues that facticity of the human rights impacts of economic globalisation increasingly undermines the normativity of the state-centred conception of international human rights law. The exposure of the international legal order of states to the operations of global business entitie

  16. The Crisis of International Human Rights Law in the Global Market Economy

    NARCIS (Netherlands)

    Augenstein, Daniel

    2014-01-01

    The article argues that the facticity of the human rights impacts of economic globalisation increasingly undermines the normativity of the state-centred conception of international human rights law. The exposure of the international legal order of states to the operations of global business entities

  17. The alliance relationship analysis of international terrorist organizations with link prediction

    Science.gov (United States)

    Fang, Ling; Fang, Haiyang; Tian, Yanfang; Yang, Tinghong; Zhao, Jing

    2017-09-01

    Terrorism is a huge public hazard of the international community. Alliances of terrorist organizations may cause more serious threat to national security and world peace. Understanding alliances between global terrorist organizations will facilitate more effective anti-terrorism collaboration between governments. Based on publicly available data, this study constructed a alliance network between terrorist organizations and analyzed the alliance relationships with link prediction. We proposed a novel index based on optimal weighted fusion of six similarity indices, in which the optimal weight is calculated by genetic algorithm. Our experimental results showed that this algorithm could achieve better results on the networks than other algorithms. Using this method, we successfully digged out 21 real terrorist organizations alliance from current data. Our experiment shows that this approach used for terrorist organizations alliance mining is effective and this study is expected to benefit the form of a more powerful anti-terrorism strategy.

  18. Human Aspect as a Critical Factor for Organization Sustainability in the Tourism Industry

    Directory of Open Access Journals (Sweden)

    Mehmet Ulus

    2016-03-01

    Full Text Available Organizations adopt diverse strategies to govern the technical and managerial aspects of sustainability implementation processes. The need for better leading and managing people-related issues emerges as companies aim for more effective change towards sustainability. The human aspect of the sustainability implementation process is mostly not paid enough attention, but it can significantly affect the success of a change management program by creating hurdles or easing the process. This study considers three human-related factors: resistance to change, internal communication, and employee engagement in sustainability activities of organizations. The aim of the study is to explore how these human factors are managed by tourism companies for organizational sustainability. For this purpose four companies from different sectors of tourism are chosen as case studies and the results are examined using qualitative data analysis techniques. The results indicate that the companies which are in a more advanced stage of sustainability implementation manage human factors using a greater number of channels and employ varied strategies. The results can provide insights into how organizations tackle the challenges of managing human aspect and display the practices that contribute to successful change management programs for achieving organizational sustainability through people.

  19. 人权国际合作的多元实践形态%Multiple Practice Forms of International Cooperation for Human Rights

    Institute of Scientific and Technical Information of China (English)

    毛俊响

    2013-01-01

    It has been general consensus in international community currently that conducting international cooperation could promote international protection for human rights. In practice, the forms of international cooperation for human rights include making human rights rules by negotiation, participation in international human rights systems, conducting technical cooperation, regional human rights systems, human right-oriented in policy-making, human rights dialogue and international human rights conferences or forums. The analysis of international cooperation for human rights shows that international cooperation for human rights not only runs throughout the whole process of formulating and implementing human rights standards, but also exists in other areas such as international trade, finance, social development and international peace and security. International cooperation for human rights is not the exclusive responsibility of nations. International governmental organizations and non-governmental organizations have become the indispensible subjects of international cooperation for human rights.%开展国际合作以促进国际人权保护已经成为当前国际社会的普遍共识。在实践中,人权国际合作体现为协商制定国际人权规则、参与国际人权机制、开展技术合作、区域人权安排、政策框架中的人权导向、人权对话与人权会议等多元形态。人权国际合作不仅贯穿于国际人权标准制定与实施的整个过程,还广泛存在于国际贸易、国际金融、社会发展以及安全合作等领域。通过国际合作来促进人权国际保护不再是国家的专属责任,国际组织、非政府组织也是人权国际合作不可或缺的主体。

  20. Marketing communication practices of public organizations to prevent human trafficking

    Directory of Open Access Journals (Sweden)

    T.M. Borysova

    2013-12-01

    Full Text Available The aim of the article. The aim of the article is to analyze marketing communicative measures against human trafficking which were implemented by public organizations in 15 regions of Ukraine in 2011-2012. There are following research objectives: to investigate what kind of campaign or program of preventing the potential victims of human trafficking has been used by Ukrainian public organizations during 2011-2012; to determine whether marketing communicative measures have been implemented on the basis of previously carried out researches for determining effective preventive methods and to find out if they were addressed to a target group of potential victims; to analyze the material used for the campaigns or programs and its dissemination. The results of the analysis. The analysis of data obtained from 15 investigated regions makes it possible to draw the following results: active informing of society about human trafficking by public organizations and authorities took place in 2011-2012, but their measures were not coordinated, communications were not integrated, without clearly defined executors, time frames, criteria of evaluation and were not based on previous researches. Monitoring of implementation of measures was not carried out by authorities. All target audiences were not reached; the choice of the target market and methodology of preventive work was based on previous researches; their actions were directed on target audiences of communications, which both are the population in general and potential victims, establishments aiding victims of trafficking in human beings, central executive authorities, local executive authorities; public organizations have used the following channels of communication: personal communications in forms of training, seminars, press-conferences, different outdoor actions, consultations on human trafficking combating by «hot line»; there is a problem of common, standardized, objective state statistics in the

  1. Speculations on the Impact of Global Electronic Networks on Human Cognition and Human Organization.

    Science.gov (United States)

    Nilan, Michael S.

    1993-01-01

    Examines the relationship between a society's communication technology and Marshall McLuhan's concerns for human cognition, and between the technology and the ways that humans organize their societies. It is suggested that appropriate development of global electronic networks could have a positive effect on individual and organizational abilities…

  2. Why Is Organizing Human Resource Development so Problematic? Perspectives from the Learning-Network Theory (Part I)

    Science.gov (United States)

    Poell, Rob F.; van der Krogt, Ferd

    2017-01-01

    Purpose: Human resource development (HRD) is an important field within management. Developing employees is often regarded as an instrument to improve the internal labor market and support organizational change. Organizing HRD to these ends, however, is frequently a problematic affair, in terms of training effectiveness, participant motivation and…

  3. Aggregatibacter actinomycetemcomitans lipopolysaccharide affects human gingival fibroblast cytoskeletal organization.

    Science.gov (United States)

    Gutiérrez-Venegas, Gloria; Contreras-Marmolejo, Luis Arturo; Román-Alvárez, Patricia; Barajas-Torres, Carolina

    2008-04-01

    The cytoskeleton is a dynamic structure that plays a key role in maintaining cell morphology and function. This study investigates the effect of bacterial wall lipopolysaccharide (LPS), a strong inflammatory agent, on the dynamics and organization of actin, tubulin, vimentin, and vinculin proteins in human gingival fibroblasts (HGF). A time-dependent study showed a noticeable change in actin architecture after 1.5 h of incubation with LPS (1 microg/ml) with the formation of orthogonal fibers and further accumulation of actin filament at the cell periphery by 24 h. When 0.01-10 microg/ml of LPS was added to human gingival fibroblast cultures, cells acquired a round, flat shape and gradually developed cytoplasmic ruffling. Lipopolysaccharides extracted from Aggregatibacter actinomycetemcomitans periodontopathogenic bacteria promoted alterations in F-actin stress fibres of human gingival cells. Normally, human gingival cells have F-actin fibres that are organized in linear distribution throughout the cells, extending along the cell's length. LPS-treated cells exhibited changes in cytoskeletal protein organization, and F-actin was reorganized by the formation of bundles underneath and parallel to the cell membrane. We also found the reorganization of the vimentin network into vimentin bundling after 1.5 h of treatment. HGF cells exhibited diffuse and granular gamma-tubulin stain. There was no change in LPS-treated HGF. However, vinculin plaques distributed in the cell body diminished after LPS treatment. We conclude that the dynamic and structured organization of cytoskeletal filaments and actin assembly in human gingival fibroblasts is altered by LPS treatment and is accompanied by a decrease in F-actin pools.

  4. The Battle for Human Organs. Organ Trafficking and Transplant Tourism in a Global Context

    NARCIS (Netherlands)

    Ambagtsheer, Frederike; Zaitch, Damian; Weimar, Willem

    2013-01-01

    While the trade in human organs remains largely in the darkness as it is hardly reported, detected or scientifically researched, a range of key institutional stakeholders, professionals, policy-makers and scholars involved in this field show remarkable high levels of moral condemnation and share a r

  5. Viability of human corneal keratocytes during organ culture

    DEFF Research Database (Denmark)

    Møller-Pedersen, T; Møller, H J

    1996-01-01

    The viability of human corneal keratocytes was assessed during four weeks of 'closed system' organ culture at 31 degrees C. After 28 days of culturing, the entire keratocyte population was still alive and viable because all cells incorporated uridine; a parameter for RNA-synthesis. During the first...... of keratan sulphate proteoglycan suggested that approximately 1% of the total content was lost during the period. In conclusion, our current organ culture technique can maintain a viable keratocyte population for four weeks; a viable stroma can be grafted within this period....

  6. PERFORMANCE MANAGEMENT IN INTERNATIONAL HUMAN RESOURCE MANAGEMENT: EVIDENCE FROM THE CEE REGION

    Directory of Open Access Journals (Sweden)

    Agneš Slavić

    2014-05-01

    Full Text Available Performance management (PM is a very important process of human resource management (HRM, in general. It implies an assessment of current or previous results or performance of the employee, team or the whole organization. It is a base for many business practices related to HRM: the need for staff training, new recruitment, career development, rewarding, etc. A wide literature sources emphasized that PM is a complex process, especially when the global market is in the scope of the research. This paper examined the performance management from the aspect of international human resource management (IHRM. The main objective of this paper was to explore the area of performance management in context of IHRM and relations between the existence of formal appraisal systems (FAS for performance management and organizational performances. The research was carried out trough literature and empirical research based on CRANET data base. Methodology used in the research included statistical techniques of descriptive statistics and independent t-test, performed with SPSS program. Authors explored data from organizations from 7 countries from the Central and Eastern Europe (CEE region.

  7. The execution of decision of international human rights jurisdictions: towards a harmonization of regional systems

    Directory of Open Access Journals (Sweden)

    Elisabeth Lambert - Abdelgawad

    2010-12-01

    Full Text Available This article, which compares the legal monitoring procedures of the judgments of the European and Inter-American Court of Human Rights, states that these regimes were initially thought of in very diverse terms. Indeed the political approach at the European level is opposed to the judicial approach adopted by the Inter-American system. This study demonstrates how through evolution, which has already occurred in Europe but is still in preparation in America, both regional systems are moving closer together towards a mixed system (judicial and political involving several organs, at the international and national levels. Facing similar cases of noncompliance (for either technical or political reasons, both systems try to reply through non punitive measures.

  8. A Condition Analysis for Advancing Exalted Level of Nuclear International Organization

    Energy Technology Data Exchange (ETDEWEB)

    Kim, H. J.; Oh, K. B.; Chung, W. S.; Lee, K. S.; Yun, S. W.; Jeong, I.; Ko, H. S.; Lee, J. H

    2008-02-15

    This paper aimed at developing the strategy for facilitating the Korean participation as a higher staff in the nuclear related international organizations. - For that purpose, this Study focused on the following three subjects ; (1) to analyze the job situation of international organizations, (2) to analyze the background information and the procedure of appointment, (3) to suggest a facilitating strategy. - There are over 40 higher staff members including Director-General, six Deputy Director-General and 36 Directors in IAEA. Analysis shows that there are three main factors which influence the appointment of those higher position; geographical distribution, members' contributions towards the regular budget and a nation's influencing power to the international community. We can categorize into two case in aspect of the agency's appointment procedure. A director's position is generally decided through the open competition. In the case of Deputy Director-General or higher position, however, it is a practice that the Agency appoints the candidates through a unofficial procedure considering political situation. - There are twelve higher staffs in NEA. Influencing power and members' contributions towards the regular budget are the major criteria of higher staff's appointment. - It is expected that this study will contribute to the facilitation of Korean participation as a higher staff in the international organization by supplying the basic strategy.

  9. A self-organized internal models architecture for coding sensory-motor schemes

    Directory of Open Access Journals (Sweden)

    Esaú eEscobar Juárez

    2016-04-01

    Full Text Available Cognitive robotics research draws inspiration from theories and models on cognition, as conceived by neuroscience or cognitive psychology, to investigate biologically plausible computational models in artificial agents. In this field, the theoretical framework of Grounded Cognition provides epistemological and methodological grounds for the computational modeling of cognition. It has been stressed in the literature that textit{simulation}, textit{prediction}, and textit{multi-modal integration} are key aspects of cognition and that computational architectures capable of putting them into play in a biologically plausible way are a necessity.Research in this direction has brought extensive empirical evidencesuggesting that textit{Internal Models} are suitable mechanisms forsensory-motor integration. However, current Internal Models architectures show several drawbacks, mainly due to the lack of a unified substrate allowing for a true sensory-motor integration space, enabling flexible and scalable ways to model cognition under the embodiment hypothesis constraints.We propose the Self-Organized Internal ModelsArchitecture (SOIMA, a computational cognitive architecture coded by means of a network of self-organized maps, implementing coupled internal models that allow modeling multi-modal sensory-motor schemes. Our approach addresses integrally the issues of current implementations of Internal Models.We discuss the design and features of the architecture, and provide empirical results on a humanoid robot that demonstrate the benefits and potentialities of the SOIMA concept for studying cognition in artificial agents.

  10. The Effects of Organic Pollutants in Soil on Human Health

    Science.gov (United States)

    Burgess, Lynn

    2013-04-01

    The soil has always been depository of the organic chemicals produced naturally or anthropogenically. Soil contamination is a serious human and environmental problem. A large body of evidence has shown the risks of adverse health effects with the exposure to contaminated soil due to the large quantities of organic chemicals used in agriculture and urban areas that have a legacy of environmental pollution linked to industrial activities, coal burning, motor vehicle emissions, waste incineration and waste dumping. In agricultural areas, because of the effort to provide adequate quantities of agricultural products, farmers have been using an increasing amount of organic chemicals, but the resulting pollution has enormous potential for environmental damage. The types of organic pollutants commonly found in soils are polychlorinated biphenyls, polybrominated biphenyls, polychlorinated dibenzofurans, polycyclic aromatic hydrocarbons, organophosphorus and carbamate insecticides, herbicides and organic fuels, especially gasoline and diesel. Another source of soil pollution is the complex mixture of organic chemicals, metals and microorganisms in the effluent from septic systems, animal wastes and other sources of biowaste. The soils of the world are a vast mixture of chemicals and although conditions are such that an individual is rarely exposed to a single compound, the great majority of people are exposed to a vast chemical mixture of organics, their metabolites, and other compounds at low concentrations Human exposure to organic pollutants in the soil is an area of toxicology that is very difficult to study due to the low concentration of the pollutants. The toxicological studies of single organic pollutants found in soils are limited and research on the metabolites and of chemical mixtures is very limited. The majority of toxicological studies are conducted at relatively high doses and for short periods of exposure. This makes the application of this data to exposure

  11. Human Resource Utilization and Internal Efficiency in State-Owned Universities in Nigeria

    OpenAIRE

    A.Y. Abdulkareem; Fasasi, Y. A.; O.P. Akinnubi

    2011-01-01

    This paper examined the relationship between human resource utilization and internal efficiency in Nigerian state universities. It was a descriptive survey research. Stratified random sampling technique was adopted for selecting 6 out of 12 state-owned universities. Also, 572 lecturers were sampled from Humanities and Science Faculties of the institutions. They responded to “Human Resource Checklist” (HRC) and “Internal Efficiency Checklist” (IEC) designed by the researchers and validated by ...

  12. The bi-functional organization of human basement membranes.

    Science.gov (United States)

    Halfter, Willi; Monnier, Christophe; Müller, David; Oertle, Philipp; Uechi, Guy; Balasubramani, Manimalha; Safi, Farhad; Lim, Roderick; Loparic, Marko; Henrich, Paul Bernhard

    2013-01-01

    The current basement membrane (BM) model proposes a single-layered extracellular matrix (ECM) sheet that is predominantly composed of laminins, collagen IVs and proteoglycans. The present data show that BM proteins and their domains are asymmetrically organized providing human BMs with side-specific properties: A) isolated human BMs roll up in a side-specific pattern, with the epithelial side facing outward and the stromal side inward. The rolling is independent of the curvature of the tissue from which the BMs were isolated. B) The epithelial side of BMs is twice as stiff as the stromal side, and C) epithelial cells adhere to the epithelial side of BMs only. Side-selective cell adhesion was also confirmed for BMs from mice and from chick embryos. We propose that the bi-functional organization of BMs is an inherent property of BMs and helps build the basic tissue architecture of metazoans with alternating epithelial and connective tissue layers.

  13. The bi-functional organization of human basement membranes.

    Directory of Open Access Journals (Sweden)

    Willi Halfter

    Full Text Available The current basement membrane (BM model proposes a single-layered extracellular matrix (ECM sheet that is predominantly composed of laminins, collagen IVs and proteoglycans. The present data show that BM proteins and their domains are asymmetrically organized providing human BMs with side-specific properties: A isolated human BMs roll up in a side-specific pattern, with the epithelial side facing outward and the stromal side inward. The rolling is independent of the curvature of the tissue from which the BMs were isolated. B The epithelial side of BMs is twice as stiff as the stromal side, and C epithelial cells adhere to the epithelial side of BMs only. Side-selective cell adhesion was also confirmed for BMs from mice and from chick embryos. We propose that the bi-functional organization of BMs is an inherent property of BMs and helps build the basic tissue architecture of metazoans with alternating epithelial and connective tissue layers.

  14. A quick indicator of effectiveness of “capacity building” initiatives of NGOs and international organizations

    Directory of Open Access Journals (Sweden)

    David Lempert

    2015-12-01

    Full Text Available The article offers an easy-to-use indicator for scholars and practitioners to measure whether NGOs, international organizations, and government policies and projects meet the criteria for design and implementation of “capacity building” projects that have been established by various international organizations and that are recognized by experts in the field. The indicator can be used directly to address failures that are routinely reported in this key and growing development intervention. Use of this indicator on more than a dozen standard interventions funded today by international development banks, UN organizations, country donors, and non-governmental organizations (NGOs reveals that while many smaller organizations are working to change institutions and society in ways that effectively build long-term capacity, most of the major actors in the field of development have failed to follow their own guidelines. Many appear to be using “capacity building” as a cover for lobbying foreign governments to promote international agendas (“purchasing foreign officials” and/or to increase the power of particular officials at the expense of democracy, with the public lacking simple accountability tools. The indicator points to specific areas for holding development actors accountable in order to promote development goals of sustainability and good governance. The breadth of the field of “capacity building” also allows this indicator to be used, with some modifications, for a large variety of development interventions. This article also offers several examples of where current capacity building projects fail, along with a sample test of the indicator using UNCDF as a case study.

  15. Introduction of the World Health Organization project of the International Classification of Traditional Medicine.

    Science.gov (United States)

    Gao, Peng-fei; Watanabe, Kenji

    2011-11-01

    The World Health Organization plans to incorporate "traditional medicine" into the next revision of its International Classification of Diseases-Version 11 (ICD-11). If traditional medicine is included in ICD-11, it is definitely an epoch-making issue. The expected result is the International Classification of Traditional Medicine, China, Japan and Korea Version (ICTM-CJK). The intention of the ICTM project is not only beneficial for traditional medical components, but also might be beneficial for Western biomedicine. For this shared purpose, China, Japan and Korea must understand the meaning of this project and collaborate to develop it.

  16. High-internal-phase emulsions stabilized by metal-organic frameworks and derivation of ultralight metal-organic aerogels

    Science.gov (United States)

    Zhang, Bingxing; Zhang, Jianling; Liu, Chengcheng; Peng, Li; Sang, Xinxin; Han, Buxing; Ma, Xue; Luo, Tian; Tan, Xiuniang; Yang, Guanying

    2016-01-01

    To design high-internal-phase emulsion (HIPE) systems is of great interest from the viewpoints of both fundamental researches and practical applications. Here we demonstrate for the first time the utilization of metal-organic framework (MOF) for HIPE formation. By stirring the mixture of water, oil and MOF at room temperature, the HIPE stabilized by the assembly of MOF nanocrystals at oil-water interface could be formed. The MOF-stabilized HIPE provides a novel route to produce highly porous metal-organic aerogel (MOA) monolith. After removing the liquids from the MOF-stabilized HIPE, the ultralight MOA with density as low as 0.01 g·cm−3 was obtained. The HIPE approach for MOA formation has unique advantages and is versatile in producing different kinds of ultralight MOAs with tunable porosities and structures. PMID:26892258

  17. Humans on the International Space Station-How Research, Operations, and International Collaboration are Leading to New Understanding of Human Physiology and Performance in Microgravity

    Science.gov (United States)

    Ronbinson, Julie A.; Harm, Deborah L.

    2009-01-01

    As the International Space Station (ISS) nears completion, and full international utilization is achieved, we are at a scientific crossroads. ISS is the premier location for research aimed at understanding the effects of microgravity on the human body. For applications to future human exploration, it is key for validation, quantification, and mitigation of a wide variety of spaceflight risks to health and human performance. Understanding and mitigating these risks is the focus of NASA s Human Research Program. However, NASA s approach to defining human research objectives is only one of many approaches within the ISS international partnership (including Roscosmos, the European Space Agency, the Canadian Space Agency, and the Japan Aerospace Exploration Agency). Each of these agencies selects and implements their own ISS research, with independent but related objectives for human and life sciences research. Because the science itself is also international and collaborative, investigations that are led by one ISS partner also often include cooperative scientists from around the world. The operation of the ISS generates significant additional data that is not directly linked to specific investigations. Such data comes from medical monitoring of crew members, life support and radiation monitoring, and from the systems that have been implemented to protect the health of the crew (such as exercise hardware). We provide examples of these international synergies in human research on ISS and highlight key early accomplishments that derive from these broad interfaces. Taken as a whole, the combination of diverse research objectives, operational data, international sharing of research resources on ISS, and scientific collaboration provide a robust research approach and capability that no one partner could achieve alone.

  18. Humans on the International Space Station-How Research, Operations, and International Collaboration are Leading to New Understanding of Human Physiology and Performance in Microgravity

    Science.gov (United States)

    Ronbinson, Julie A.; Harm, Deborah L.

    2009-01-01

    As the International Space Station (ISS) nears completion, and full international utilization is achieved, we are at a scientific crossroads. ISS is the premier location for research aimed at understanding the effects of microgravity on the human body. For applications to future human exploration, it is key for validation, quantification, and mitigation of a wide variety of spaceflight risks to health and human performance. Understanding and mitigating these risks is the focus of NASA s Human Research Program. However, NASA s approach to defining human research objectives is only one of many approaches within the ISS international partnership (including Roscosmos, the European Space Agency, the Canadian Space Agency, and the Japan Aerospace Exploration Agency). Each of these agencies selects and implements their own ISS research, with independent but related objectives for human and life sciences research. Because the science itself is also international and collaborative, investigations that are led by one ISS partner also often include cooperative scientists from around the world. The operation of the ISS generates significant additional data that is not directly linked to specific investigations. Such data comes from medical monitoring of crew members, life support and radiation monitoring, and from the systems that have been implemented to protect the health of the crew (such as exercise hardware). We provide examples of these international synergies in human research on ISS and highlight key early accomplishments that derive from these broad interfaces. Taken as a whole, the combination of diverse research objectives, operational data, international sharing of research resources on ISS, and scientific collaboration provide a robust research approach and capability that no one partner could achieve alone.

  19. Generation of human organs in pigs via interspecies blastocyst complementation.

    Science.gov (United States)

    Wu, J; Platero Luengo, A; Gil, M A; Suzuki, K; Cuello, C; Morales Valencia, M; Parrilla, I; Martinez, C A; Nohalez, A; Roca, J; Martinez, E A; Izpisua Belmonte, J C

    2016-10-01

    More than eighteen years have passed since the first derivation of human embryonic stem cells (ESCs), but their clinical use is still met with several challenges, such as ethical concerns regarding the need of human embryos, tissue rejection after transplantation and tumour formation. The generation of human induced pluripotent stem cells (iPSCs) enables the access to patient-derived pluripotent stem cells (PSCs) and opens the door for personalized medicine as tissues/organs can potentially be generated from the same genetic background as the patient recipients, thus avoiding immune rejections or complication of immunosuppression strategies. In this regard, successful replacement, or augmentation, of the function of damaged tissue by patient-derived differentiated stem cells provides a promising cell replacement therapy for many devastating human diseases. Although human iPSCs can proliferate unlimitedly in culture and harbour the potential to generate all cell types in the adult body, currently, the functionality of differentiated cells is limited. An alternative strategy to realize the full potential of human iPSC for regenerative medicine is the in vivo tissue generation in large animal species via interspecies blastocyst complementation. As this technology is still in its infancy and there remains more questions than answers, thus in this review, we mainly focus the discussion on the conceptual framework, the emerging technologies and recent advances involved with interspecies blastocyst complementation, and will refer the readers to other more in-depth reviews on dynamic pluripotent stem cell states, genome editing and interspecies chimeras. Likewise, other emerging alternatives to combat the growing shortage of human organs, such as xenotransplantation or tissue engineering, topics that has been extensively reviewed, will not be covered here.

  20. Smallholder group certification in Uganda – Analysis of internal control systems in two organic export companies

    Directory of Open Access Journals (Sweden)

    Moritz Reckling

    2010-04-01

    Full Text Available The organic agricultural sector of Uganda is among the most developed in Africa in terms of its professional institutional network and high growth rates of number of certified farmers and land area. Smallholder farmers are certified organic through contract production for export companies using a group certification scheme (internal control system - ICS. The ICS is a viable and well-accepted tool to certify small-scale producers in developing countries all over the world. Difficulties in certification are still stated to be among the main constraints for Uganda’s organic sector development. Therefore, this paper reports a qualitative case study comprising 34 expert interviews in two organic fresh-produce export companies in central Uganda, aiming to explore the challenges which underlie organic certification with ICS. The study shows that farmers cannot be labelled as ‘organic by default’ but deliberately engage in organic production as a marketing strategy. The small quantities purchased by the organic companies lead to a difficult marketing situation for the farmers, causing production and infiltration risks on the farm level. These risks require increased control that challenges the companies organizationally. The risks and control needs are a reason to involve farmers in ICS procedures and innovatively adapt the ICS by means of a bypass around formal perspective restrictions. The paper discusses different perspectives on risks, risk control and certification.

  1. Determination of organic chemicals in human whole blood: preliminary method development for volatile organics

    Energy Technology Data Exchange (ETDEWEB)

    Cramer, P.H.; Boggess, K.E.; Hosenfeld, J.M.; Remmers, J.C.; Breen, J.J.; Robinson, P.E.; Stroup, C.

    1988-04-01

    This article introduces a method for the detection and confirmation of selected volatile organics at parts-per-trillion (ppt) levels in whole human blood. Intended for routine use, the method consists of a dynamic headspace purge of water-diluted blood where a carrier gas sweeps the surface of the sample and removes a quantifiable amount of the volatile organics from the blood and into an adsorbent trap. The organics are thermally desorbed form the adsorbent trap and onto the analytical column in a gas-chromatographic/mass-spectrometric (GC/MS) system where limited mass-scan data are taken for qualitative and quantitative identification. The method can be employed for compounds normally defined as volatile organics, such as those on the EPA priority-pollutant-volatiles list. Method validation results and limited population-survey results are also presented here.

  2. Self-organization in Complex Systems The Past, Present, and Future of Synergetics : International Symposium

    CERN Document Server

    Pelster, Axel

    2016-01-01

    This proceedings volume contains talks and poster presentations from the International Symposium "Self-Organization in Complex Systems: The Past, Present, and Future of Synergetics", which took place at Hanse-Wissenschaftskolleg, an Institute of Advanced Studies, in Delmenhorst, Germany, during the period November 13 - 16, 2012. The Symposium was organized in honour of Hermann Haken, who celebrated his 85th birthday in 2012. With his fundamental theory of Synergetics he had laid the mathematical-physical basis for describing and analyzing self-organization processes in a diversity of fields of research. The quest for common and universal principles of self-organization in complex systems was clearly covered by the wide range of interdisciplinary topics reported during the Symposium. These extended from complexity in classical systems and quantum systems over self-organisation in neuroscience even to the physics of finance. Moreover, by combining a historical view with a present status report the Symposium con...

  3. Non-governmental organizations and KM: A human centric approach

    Directory of Open Access Journals (Sweden)

    Iftikhar Hussain

    2012-04-01

    Full Text Available Non-governmental organizations need to manage their knowledge similarly to for-profit organizations. Although for effective KM a technology, people, task, and structure – integrated approach is required. However, there is a strong imperative to develop people capabilities within Non-governmental organizations in order to meet the challenges of economic, social and environmental development. Therefore, in this study we have particularly examined the impact of human resources on KM effectiveness in the nonprofit industry. The study deals with three major research questions: (1 Does the level of human resources’ knowledge have a positive influence on a Non-governmental organization’s KM capabilities? (2 Does a Non-governmental organization’s KM capability positively influence its knowledge processing capability? (3 Does a Non-governmental organization’s knowledge processing capability positively influence its performance? Further, the study aims to investigate human resource management related issues in KM implementation in nonprofit industry, and attempts to provide appropriate solutions. Finally, the study proposed a KM model for nonprofit industry.

  4. Human population studies and the World Health Organization.

    Science.gov (United States)

    de Chadarevian, Soraya

    2015-01-01

    This essay draws attention to the role of the WHO in shaping research agendas in the biomedical sciences in the postwar era. It considers in particular the genetic studies of human populations that were pursued under the aegis of the WHO from the late 1950s to 1970s. The study provides insights into how human and medical genetics entered the agenda of the WHO. At the same time, the population studies become a focus for tracking changing notions of international relations, cooperation, and development and their impact on research in biology and medicine in the post-World War I era. After a brief discussion of the early history of the WHO and its position in Cold War politics, the essay considers the WHO program in radiation protection and heredity and how the genetic study of "vanishing" human populations and a world-wide genetic study of newborns fitted this broader agenda. It then considers in more detail the kind of support offered by the WHO for these projects. The essay highlights the role of single individuals in taking advantage of WHO support for pushing their research agendas while establishing a trend towards cooperative international projects in biology.

  5. Sterols of Pneumocystis carinii hominis organisms isolated from human lungs

    DEFF Research Database (Denmark)

    Kaneshiro, E S; Amit, Z; Chandra, Jan Suresh

    1999-01-01

    The opportunistic pathogen Pneumocystis carinii causes pneumonia (P. carinii pneumonia, or PCP) in immunocompromised individuals such as AIDS patients. Rat-derived P. carinii carinii organisms have distinct sterols which are not synthesized by mammals and not found in other microbes infecting...... mammalian lungs. The dominant sterol present in the organism is cholesterol (which is believed to be scavenged from the host), but other sterols in P. carinii carinii have an alkyl group at C-24 of the sterol side chain (C(28) and C(29) 24-alkylsterols) and a double bond at C-7 of the nucleus. Recently...... in conjunction with analyses of chemically synthesized authentic standards. The sterol composition of isolated P. carinii hominis organisms has yet to be reported. If P. carinii from animal models is to be used for identifying potential drug targets and for developing chemotherapeutic approaches to clear human...

  6. Organizing conceptual knowledge in humans with a gridlike code.

    Science.gov (United States)

    Constantinescu, Alexandra O; O'Reilly, Jill X; Behrens, Timothy E J

    2016-06-17

    It has been hypothesized that the brain organizes concepts into a mental map, allowing conceptual relationships to be navigated in a manner similar to that of space. Grid cells use a hexagonally symmetric code to organize spatial representations and are the likely source of a precise hexagonal symmetry in the functional magnetic resonance imaging signal. Humans navigating conceptual two-dimensional knowledge showed the same hexagonal signal in a set of brain regions markedly similar to those activated during spatial navigation. This gridlike signal is consistent across sessions acquired within an hour and more than a week apart. Our findings suggest that global relational codes may be used to organize nonspatial conceptual representations and that these codes may have a hexagonal gridlike pattern when conceptual knowledge is laid out in two continuous dimensions.

  7. Personalized development of human organs using 3D printing technology.

    Science.gov (United States)

    Radenkovic, Dina; Solouk, Atefeh; Seifalian, Alexander

    2016-02-01

    3D printing is a technique of fabricating physical models from a 3D volumetric digital image. The image is sliced and printed using a specific material into thin layers, and successive layering of the material produces a 3D model. It has already been used for printing surgical models for preoperative planning and in constructing personalized prostheses for patients. The ultimate goal is to achieve the development of functional human organs and tissues, to overcome limitations of organ transplantation created by the lack of organ donors and life-long immunosuppression. We hypothesized a precision medicine approach to human organ fabrication using 3D printed technology, in which the digital volumetric data would be collected by imaging of a patient, i.e. CT or MRI images followed by mathematical modeling to create a digital 3D image. Then a suitable biocompatible material, with an optimal resolution for cells seeding and maintenance of cell viability during the printing process, would be printed with a compatible printer type and finally implanted into the patient. Life-saving operations with 3D printed implants were already performed in patients. However, several issues need to be addressed before translational application of 3D printing into clinical medicine. These are vascularization, innervation, and financial cost of 3D printing and safety of biomaterials used for the construct.

  8. The Pacific Alliance: juridical Scrutiny of the Content of the Law of International Organizations

    Directory of Open Access Journals (Sweden)

    Santiago Díaz-Cediel

    2016-01-01

    Full Text Available Much has been said about the Pacific Alliance. It is undoubtedly the most novel process of integration in which the Republic of Colombia has participated. Nevertheless, insufficient attention has been paid to its juridical nature under international law, with the proposition of elucidating the legal consequences which will derive from it. The article starts from the content of the Law of International Organisations and considers the practice of the Ministry of External Relations of the Republic of Colombia, carrying out an evaluation of the Pacific Alliance. It examines what has been convened, to date, in treaties agreed to in their sphere -on par with the international instruments of soft law to today adopted- with the proposition of determining whether certain concurrent requisites necessary on order to comport with the juridical nature of an international organization are met. Later, it will refer to some international law consequences which emanate from the foregoing and in the Colombian internal juridical order, inter alia, incapacity to conclude treaties and the proscription of the power to mandate provisional application in the Republic of Colombia, respectively.

  9. Advancement of human rights standards for LGBT people through the perspective of international human rights law

    Directory of Open Access Journals (Sweden)

    Lucie Cviklová

    2012-01-01

    Full Text Available The article addresses the issue how various religious and legal systems cope with current developments that undermine binary opposition of man and woman including definition of their sexual and cultural identities. More concretely, it tries to explain, how concrete societies and legislations deal with claims of lesbians, gays, bisexuals, and transsexuals (LGBT that claim broader recognition. It elucidates differences among Western provisions and policies of the relevant legal bodies such as the General Assembly of the United Nations, the European Court of Human Rights and the Supreme Court concerning these issues. It also points to the nature and real impact of international civil society forces such as Yogyakarta principles that formulate extension of rights concerning lesbians, gays, bisexuals, and transsexuals. On the basis of comparison of various legal and religious discourses it explains current practices of direct and indirect discrimination and in some non-European national systems even extra-judicial killings, torture and ill-treatment, sexual assault, rape and other violations of human rights. When emphasizing substantial differences among current European states and non-European ones concerning policies toward lesbian, gay, bisexual and transgender people (LGBT, it shows current tendencies of advancement in the field by common policies of Council of Europe, recent judgments issued by the European Court of Human Rights as well as civil society efforts such as Yogyakarta principles. Swedish standards have been introduced in order to emphasize existing progressive attitudes to LGBT people concerning gay marriages and adoption procedures.

  10. Stepwise Connectivity of the Modal Cortex Reveals the Multimodal Organization of the Human Brain

    Science.gov (United States)

    Sepulcre, Jorge; Sabuncu, Mert R.; Yeo, Thomas B.; Liu, Hesheng; Johnson, Keith A.

    2012-01-01

    How human beings integrate information from external sources and internal cognition to produce a coherent experience is still not well understood. During the past decades, anatomical, neurophysiological and neuroimaging research in multimodal integration have stood out in the effort to understand the perceptual binding properties of the brain. Areas in the human lateral occipito-temporal, prefrontal and posterior parietal cortices have been associated with sensory multimodal processing. Even though this, rather patchy, organization of brain regions gives us a glimpse of the perceptual convergence, the articulation of the flow of information from modality-related to the more parallel cognitive processing systems remains elusive. Using a method called Stepwise Functional Connectivity analysis, the present study analyzes the functional connectome and transitions from primary sensory cortices to higher-order brain systems. We identify the large-scale multimodal integration network and essential connectivity axes for perceptual integration in the human brain. PMID:22855814

  11. Susceptibility of human populations to environmental exposure to organic contaminants.

    Science.gov (United States)

    Undeman, Emma; Brown, Trevor N; Wania, Frank; McLachlan, Michael S

    2010-08-15

    Environmental exposure to organic contaminants is a complex function of environmental conditions, food chain characteristics, and chemical properties. In this study the susceptibility of various human populations to environmental exposure to neutral organic contaminants was compared. An environmental fate model and a linked bioaccumulation model were parametrized to describe ecosystems in different climatic regions (temperate, arctic, tropical, and steppe). The human body burden resulting from constant emissions of hypothetical chemicals was estimated for each region. An exposure susceptibility index was defined as the body burden in the region of interest normalized to the burden of the same chemical in a reference human from the temperate region eating an average diet. For most persistent chemicals emitted to air, the Arctic had the highest susceptibility index (max 520). Susceptibility to exposure was largely determined by the food web properties. The properties of the physical environment only had a marked effect when air or water, not food, was the dominant source of human exposure. Shifting the mode of emission markedly changed the relative susceptibility of the ecosystems in some cases. The exposure arising from chemical use clearly varies between ecosystems, which makes an understanding of ecosystem susceptibility to exposure important for chemicals management.

  12. 2012 International Conference on Human-centric Computing

    CERN Document Server

    Jin, Qun; Yeo, Martin; Hu, Bin; Human Centric Technology and Service in Smart Space, HumanCom 2012

    2012-01-01

    The theme of HumanCom is focused on the various aspects of human-centric computing for advances in computer science and its applications and provides an opportunity for academic and industry professionals to discuss the latest issues and progress in the area of human-centric computing. In addition, the conference will publish high quality papers which are closely related to the various theories and practical applications in human-centric computing. Furthermore, we expect that the conference and its publications will be a trigger for further related research and technology improvements in this important subject.

  13. WIAMan Technology Demonstrator Sensor Codes Conforming to International Organization for Standardization/Technical Standard (ISO/TS) 13499

    Science.gov (United States)

    2016-03-01

    Standardization/Technical Standard ( ISO /TS) 13499 by Michael Tegtmeyer Approved for public release; distribution is unlimited. NOTICES Disclaimers The findings...International Organization for Standardization/Technical Standard ( ISO /TS) 13499 by Michael TegtmeyerWIAMan Engineering Office, ARL Approved for public...WIAMan Technology Demonstrator Sensor Codes Conforming to International Organization for Standardization/Technical Standard ( ISO /TS) 13499 Michael

  14. The Diffusion of Educational Ideas among International Organizations: An Event History Analysis of Lifelong Learning, 1990-2013

    Science.gov (United States)

    Zapp, Mike; Dahmen, Clarissa

    2017-01-01

    This article investigates the precipitants of the diffusion of lifelong learning among 88 governmental and nongovernmental international organizations from 1990 to 2013 within an event history framework. Research on the diffusion of educational ideas among and within international organizations usually uses small-n approaches. This work looks at…

  15. 10 CFR 1004.11 - Handling information of a private business, foreign government, or an international organization.

    Science.gov (United States)

    2010-01-01

    ..., or an international organization. (a) Whenever a document submitted to the DOE contains information... 10 Energy 4 2010-01-01 2010-01-01 false Handling information of a private business, foreign government, or an international organization. 1004.11 Section 1004.11 Energy DEPARTMENT OF ENERGY (GENERAL...

  16. The International Labor Organization and Union freedom in Latin America: The case of Venezuela in 1949

    Directory of Open Access Journals (Sweden)

    Juan Carlos Yáñez Andrade

    2017-02-01

    Full Text Available This article analyzes the relationship between the International Labor Organization (ILO and the trade union movement in Latin America. If attempts to strengthen the workers' movement were long-standing, during the 1930s relations between the Latin American trade union movement and the ILO began to become more regular, especially in international forums. Special attention deserves the assistance mission carried out by the ILO in Venezuela in 1949 to study the situation of workers' organizations after the establishment of the military dictatorship of General Carlos Delgado (1948. Document relevant is the report written by the mission led by Jef Rens, Assistant Director General of the ILO, and published in 1949.

  17. [The transition from 'international' to 'global' public health and the World Health Organization].

    Science.gov (United States)

    Brown, Theodore M; Cueto, Marcos; Fee, Elizabeth

    2006-01-01

    Within the context of international public health, 'global health' seems to be emerging as a recognized term of preference. This article presents a critical analysis of the meaning and importance of 'global health' and situates its growing popularity within a historical context. A specific focus of this work is the role of the World Health Organization - WHO in both 'international' and 'global' health, and as na agent of transition from one to the other. Between 1948 and 1998, the WHO went through a period of hardship as it came up against an organizational crisis, budget cuts and a diminished status, especially when confronted with the growing influence of new, power players like the World Bank. We suggest that the WHO has responded to this changing international context by inititating its own process of restructuring and repositioning as an agent for coordinating, strategically planning and leading 'global health' initiatives.

  18. THE IMPACT of CULTURE, LEADERSHIP, and POWER, on STAFF MOTIVATION in the CONTEXT of INTERNATIONAL ORGANIZATIONS

    OpenAIRE

    Erciyes, Erdem

    2017-01-01

    This thesis investigates the impact of culture, leadership, and power, on staff motivation in selected international organizations (IOs), and develops a theoretical framework to assist with the practice of workforce motivation. The main research question is: “How can supervisors motivate their staff in the context of IOs?” Utilizing critical theory as a paradigm of inquiry, the study’s philosophical perspective leans heavily on “phenomenology”. Conducting this research led to the realization ...

  19. Re-organization Impact on the Telekom Malaysias International Division Productivity

    OpenAIRE

    Ahasanul Haque; Ali Khatibi; Khaizura Karim

    2005-01-01

    International Divisions productivity was perceived to incline towards a downward trend which was contravened in 1996 re-organization objective of Telekom Malaysia. This study aims to analyze the root causes of this setback and recommend the solutions to improve the companys productivity. The method to diagnose the root cause was done through surveys and interviews. The data collection was carried out through questionnaire consisting of 85 questions. Total of 171 respondents from the internati...

  20. History of the Internal Control System at the Association of Organic Cacao Farmers (APKO) in Pidie

    OpenAIRE

    Mulyadi, Tommy

    2014-01-01

    Plenty of Activities, but Limited Funding and Reliable Resources. Another big problem faced by ICS is weeds and diseases that attack cacao trees. The farmers are not used to the organic farming practice of mechanical or manual weeding, instead of using herbicides. The farmers are also eager to apply chemicals to control cacao plant diseases. It requires constant monitoring of ICS staff, who must continually inform the cooperative of internal problems, verbally or in writing, in every meeting.